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Sample records for monitor prm operational

  1. Large-Scale Targeted Proteomics Using Internal Standard Triggered-Parallel Reaction Monitoring (IS-PRM).

    Science.gov (United States)

    Gallien, Sebastien; Kim, Sang Yoon; Domon, Bruno

    2015-06-01

    Targeted high-resolution and accurate mass analyses performed on fast sequencing mass spectrometers have opened new avenues for quantitative proteomics. More specifically, parallel reaction monitoring (PRM) implemented on quadrupole-orbitrap instruments exhibits exquisite selectivity to discriminate interferences from analytes. Furthermore, the instrument trapping capability enhances the sensitivity of the measurements. The PRM technique, applied to the analysis of limited peptide sets (typically 50 peptides or less) in a complex matrix, resulted in an improved detection and quantification performance as compared with the reference method of selected reaction monitoring performed on triple quadrupole instruments. However, the implementation of PRM for the analysis of large peptide numbers requires the adjustment of mass spectrometry acquisition parameters, which affects dramatically the quality of the generated data, and thus the overall output of an experiment. A newly designed data acquisition scheme enabled the analysis of moderate-to-large peptide numbers while retaining a high performance level. This new method, called internal standard triggered-parallel reaction monitoring (IS-PRM), relies on added internal standards and the on-the-fly adjustment of acquisition parameters to drive in real-time measurement of endogenous peptides. The acquisition time management was designed to maximize the effective time devoted to measure the analytes in a time-scheduled targeted experiment. The data acquisition scheme alternates between two PRM modes: a fast low-resolution "watch mode" and a "quantitative mode" using optimized parameters ensuring data quality. The IS-PRM method exhibited a highly effective use of the instrument time. Applied to the analysis of large peptide sets (up to 600) in complex samples, the method showed an unprecedented combination of scale and analytical performance, with limits of quantification in the low amol range. The successful analysis of

  2. Comparison of targeted peptide quantification assays for reductive dehalogenases by selective reaction monitoring (SRM) and precursor reaction monitoring (PRM).

    Science.gov (United States)

    Schiffmann, Christian; Hansen, Rasmus; Baumann, Sven; Kublik, Anja; Nielsen, Per Halkjær; Adrian, Lorenz; von Bergen, Martin; Jehmlich, Nico; Seifert, Jana

    2014-01-01

    Targeted absolute protein quantification yields valuable information about physiological adaptation of organisms and is thereby of high interest. Especially for this purpose, two proteomic mass spectrometry-based techniques namely selective reaction monitoring (SRM) and precursor reaction monitoring (PRM) are commonly applied. The objective of this study was to establish an optimal quantification assay for proteins with the focus on those involved in housekeeping functions and putative reductive dehalogenase proteins from the strictly anaerobic bacterium Dehalococcoides mccartyi strain CBDB1. This microbe is small and slow-growing; hence, it provides little biomass for comprehensive proteomic analysis. We therefore compared SRM and PRM techniques. Eleven peptides were successfully quantified by both methods. In addition, six peptides were solely quantified by SRM and four by PRM, respectively. Peptides were spiked into a background of Escherichia coli lysate and the majority of peptides were quantifiable down to 500 amol absolute on column by both methods. Peptide quantification in CBDB1 lysate resulted in the detection of 15 peptides using SRM and 14 peptides with the PRM assay. Resulting quantification of five dehalogenases revealed copy numbers of <10 to 115 protein molecules per cell indicating clear differences in abundance of RdhA proteins during growth on hexachlorobenzene. Our results indicated that both methods show comparable sensitivity and that the combination of the mass spectrometry assays resulted in higher peptide coverage and thus more reliable protein quantification.

  3. New Insights into the Phage Genetic Switch: Effects of Bacteriophage Lambda Operator Mutations on DNA Looping and Regulation of PR, PL, and PRM.

    Science.gov (United States)

    Lewis, Dale E A; Gussin, Gary N; Adhya, Sankar

    2016-11-06

    One of the best understood systems in genetic regulatory biology is the so-called "genetic switch" that determines the choice the phage-encoded CI repressor binds cooperatively to tripartite operators, OL and OR, in a defined pattern, thus blocking the transcription at two lytic promoters, PL and PR, and auto-regulating the promoter, PRM, which directs CI synthesis by the prophage. Fine-tuning of the maintenance of lysogeny is facilitated by interactions between CI dimers bound to OR and OL through the formation of a loop by the intervening DNA segment. By using a purified in vitro transcription system, we have genetically dissected the roles of individual operator sites in the formation of the DNA loop and thus have gained several new and unexpected insights into the system. First, although both OR and OL are tripartite, the presence of only a single active CI binding site in one of the two operators is sufficient for DNA loop formation. Second, in PL, unlike in PR, the promoter distal operator site, OL3, is sufficient to directly repress PL. Third, DNA looping mediated by the formation of CI octamers arising through the interaction of pairs of dimers bound to adjacent operator sites in OR and OL does not require OR and OL to be aligned "in register", that is, CI bound to "out-of-register" sub-operators, for example, OL1~Ol2 and OR2~OR3, can also mediate loop formation. Finally, based on an examination of the mechanism of activation of PRM when only OR1 or OR2 are wild type, we hypothesize that RNA polymerase bound at PR interferes with DNA loop formation. Thus, the formation of DNA loops involves potential interactions between proteins bound at numerous cis-acting sites, which therefore very subtly contribute to the regulation of the "switch".

  4. Viable offspring obtained from Prm1-deficient sperm in mice

    OpenAIRE

    Naoki Takeda; Kazuya Yoshinaga; Kenryo Furushima; Kazufumi Takamune; Zhenghua Li; Shin-ichi Abe; Shin-ichi Aizawa; Ken-ichi Yamamura

    2016-01-01

    Protamines are expressed in the spermatid nucleus and allow denser packaging of DNA compared with histones. Disruption of the coding sequence of one allele of either protamine 1 (Prm1) or Prm2 results in failure to produce offspring, although sperm with disrupted Prm1 or Prm2 alleles are produced. Here, we produced Prm1-deficient female chimeric mice carrying Prm1-deficient oocytes. These mice successfully produced Prm1 +/− male mice. Healthy Prm1 +/− offspring were then produced by transferr...

  5. Remote monitoring of pipeline operations

    Energy Technology Data Exchange (ETDEWEB)

    Bost, R.C. [ERM-Southwest, Inc., Houston, TX (United States); White, D. [Glenrose Systems, Austin, TX (United States)

    1995-12-31

    The demands for monitoring of pipeline operations have recently increased greatly due to new regulatory requirements. Most companies rely upon conventional System Control and Data Acquisition (SCADA) system architecture to meet their needs. Current systems are often plagued by limited data conversion and processing capacity at the workstations. A state-of-the-art Data Acquisition Node (DAN) that relieves the workstation of much of its workload is described in this paper. Use of this DAN may eliminate the need for installing completely new systems. It facilitates marrying foreign devices to existing operation monitoring systems to satisfy new regulatory requirements. The DAN allows a system to utilize commercial communications satellites or other communication networks and real-time, object oriented programming and different devices and data requirements without the necessity of custom software development.

  6. Viable offspring obtained from Prm1-deficient sperm in mice.

    Science.gov (United States)

    Takeda, Naoki; Yoshinaga, Kazuya; Furushima, Kenryo; Takamune, Kazufumi; Li, Zhenghua; Abe, Shin-Ichi; Aizawa, Shin-Ichi; Yamamura, Ken-Ichi

    2016-06-02

    Protamines are expressed in the spermatid nucleus and allow denser packaging of DNA compared with histones. Disruption of the coding sequence of one allele of either protamine 1 (Prm1) or Prm2 results in failure to produce offspring, although sperm with disrupted Prm1 or Prm2 alleles are produced. Here, we produced Prm1-deficient female chimeric mice carrying Prm1-deficient oocytes. These mice successfully produced Prm1(+/-) male mice. Healthy Prm1(+/-) offspring were then produced by transferring blastocysts obtained via in vitro fertilization using zona-free oocytes and sperm from Prm1(+/-) mice. This result suggests that sperm lacking Prm1 can generate offspring despite being abnormally shaped and having destabilised DNA, decondensed chromatin and a reduction in mitochondrial membrane potential. Nevertheless, these mice showed little derangement of expression profiles.

  7. SENTINEL-1 RESULTS: SEA ICE OPERATIONAL MONITORING

    DEFF Research Database (Denmark)

    Toudal Pedersen, Leif; Saldo, Roberto; Fenger-Nielsen, Rasmus

    2015-01-01

    In the present paper we demonstrate the capabilities of the Sentinel-1 SAR data for operational sea-ice and iceberg monitoring. Most of the examples are drawn from the Copernicus Marine Environmental Monitoring Service (CMEMS) production.......In the present paper we demonstrate the capabilities of the Sentinel-1 SAR data for operational sea-ice and iceberg monitoring. Most of the examples are drawn from the Copernicus Marine Environmental Monitoring Service (CMEMS) production....

  8. Condition Monitoring Of Operating Pipelines With Operational Modal Analysis Application

    Directory of Open Access Journals (Sweden)

    Mironov Aleksey

    2015-12-01

    Full Text Available In the petroleum, natural gas and petrochemical industries, great attention is being paid to safety, reliability and maintainability of equipment. There are a number of technologies to monitor, control, and maintain gas, oil, water, and sewer pipelines. The paper focuses on operational modal analysis (OMA application for condition monitoring of operating pipelines. Special focus is on the topicality of OMA for definition of the dynamic features of the pipeline (frequencies and mode shapes in operation. The research was conducted using two operating laboratory models imitated a part of the operating pipeline. The results of finite-element modeling, identification of pipe natural modes and its modification under the influence of virtual failure are discussed. The work considers the results of experimental research of dynamic behavior of the operating pipe models using one of OMA techniques and comparing dynamic properties with the modeled data. The study results demonstrate sensitivity of modal shape parameters to modification of operating pipeline technical state. Two strategies of pipeline repair – with continuously condition-based monitoring with proposed technology and without such monitoring, was discussed. Markov chain reliability models for each strategy were analyzed and reliability improvement factor for proposed technology of monitoring in compare with traditional one was evaluated. It is resumed about ability of operating pipeline condition monitoring by measuring dynamic deformations of the operating pipe and OMA techniques application for dynamic properties extraction.

  9. Monitored Geologic Repository Operations Monitoring and Control System Description Document

    Energy Technology Data Exchange (ETDEWEB)

    E.F. Loros

    2000-06-29

    The Monitored Geologic Repository Operations Monitoring and Control System provides supervisory control, monitoring, and selected remote control of primary and secondary repository operations. Primary repository operations consist of both surface and subsurface activities relating to high-level waste receipt, preparation, and emplacement. Secondary repository operations consist of support operations for waste handling and treatment, utilities, subsurface construction, and other selected ancillary activities. Remote control of the subsurface emplacement operations, as well as, repository performance confirmation operations are the direct responsibility of the system. In addition, the system monitors parameters such as radiological data, air quality data, fire detection status, meteorological conditions, unauthorized access, and abnormal operating conditions, to ensure a safe workplace for personnel. Parameters are displayed in a real-time manner to human operators regarding surface and subsurface conditions. The system performs supervisory monitoring and control for both important to safety and non-safety systems. The system provides repository operational information, alarm capability, and human operator response messages during emergency response situations. The system also includes logic control to place equipment, systems, and utilities in a safe operational mode or complete shutdown during emergency response situations. The system initiates alarms and provides operational data to enable appropriate actions at the local level in support of emergency response, radiological protection response, evacuation, and underground rescue. The system provides data communications, data processing, managerial reports, data storage, and data analysis. This system's primary surface and subsurface operator consoles, for both supervisory and remote control activities, will be located in a Central Control Center (CCC) inside one of the surface facility buildings. The system

  10. Musculoskeletal perioperative problems. The role of physical and rehabilitation medicine physicians. The European perspective based on the best evidence. A paper by the UEMS-PRM Section Professional Practice Committee.

    Science.gov (United States)

    Varela, E; Oral, A; Ilieva, E; Küçükdeveci, A A; Valero, R; Berteanu, M; Christodoulou, N

    2013-10-01

    One of the objectives of the Professional Practice Committee (PPC) of the Physical and Rehabilitation Medicine (PRM) Section of the Union of European Medical Specialists (UEMS) is the development of the field of competence of PRM physicians in Europe. To achieve this objective, UEMS PRM Section PPC has adopted a systematic action plan of preparing a series of papers describing the role of PRM physicians in a number of disabling health conditions, based on the evidence of effectiveness of the physical and rehabilitation medicine interventions. According to the UEMS-PRM section, the role of PRM physician in musculoskeletal perioperative settings has to be situated inside general pain management. Musculoskeletal surgery (MSS) represents a frequent medical situation among patients suffering from musculoskeletal disorders (MSDs), in which PRM physicians need to be involved. A wide number of MSDs have to be operated in order to diminish disability and relieve symptoms, thus improving the patient´s functioning and social participation: Joint replacements, spine decompressions, vertebroplasties, internal fixation of unstable fractures, arthroscopies for tendon and joint repairs, and others. This paper describes the role of the PRM physician during the perioperative period. A well-coordinated rehabilitation programme followed by a good home rehabilitation programme results in pain reduction, faster recovery with better patient participation and increased cost effectiveness. PRM physicians have to identify patients at risk of continuing activity limitation and participation restriction who will benefit from an early rehabilitation process and formulate a PRM programme of care taking into account each patient's environmental factors.

  11. Operational Monitoring of Data Production at KNMI

    Science.gov (United States)

    van de Vegte, John; Kwidama, Anecita; van Moosel, Wim; Oosterhof, Rijk; de Wit de Wit, Ronny; Klein Ikkink, Henk Jan; Som de Cerff, Wim; Verhoef, Hans; Koutek, Michal; Duin, Frank; van der Neut, Ian; verhagen, Robert; Wollerich, Rene

    2016-04-01

    Within KNMI a new fully automated system for monitoring the KNMI operational data production systems is being developed: PRISMA (PRocessflow Infrastructure Surveillance and Monitoring Application). Currently the KNMI operational (24/7) production systems consist of over 60 applications, running on different hardware systems and platforms. They are interlinked for the production of numerous data products, which are delivered to internal and external customers. Traditionally these applications are individually monitored by different applications or not at all; complicating root cause and impact analysis. Also, the underlying hardware and network is monitored via an isolated application. Goal of the PRISMA system is to enable production chain monitoring, which enables root cause analysis (what is the root cause of the disruption) and impact analysis (what downstream products/customers will be effected). The PRISMA system will make it possible to reduce existing monitoring applications and provides one interface for monitoring the data production. For modeling and storing the state of the production chains a graph database is used. The model is automatically updated by the applications and systems which are to be monitored. The graph models enables root cause and impact analysis. In the PRISMA web interface interaction with the graph model is accomplished via a graphical representation. The presentation will focus on aspects of: • Modeling real world computers, applications, products to a conceptual model; • Architecture of the system; • Configuration information and (real world) event handling of the to be monitored objects; • Implementation rules for root cause and impact analysis. • How PRISMA was developed (methodology, facts, results) • Presentation of the PRISMA system as it now looks and works

  12. 49 CFR 193.2507 - Monitoring operations.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Monitoring operations. 193.2507 Section 193.2507 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY LIQUEFIED NATURAL GAS FACILITIES...

  13. Operation of International Monitoring System Network

    Science.gov (United States)

    Nikolova, Svetlana; Araujo, Fernando; Aktas, Kadircan; Malakhova, Marina; Otsuka, Riyo; Han, Dongmei; Assef, Thierry; Nava, Elisabetta; Mickevicius, Sigitas; Agrebi, Abdelouaheb

    2015-04-01

    The IMS is a globally distributed network of monitoring facilities using sensors from four technologies: seismic, hydroacoustic, infrasound and radionuclide. It is designed to detect the seismic and acoustic waves produced by nuclear test explosions and the subsequently released radioactive isotopes. Monitoring stations transmit their data to the IDC in Vienna, Austria, over a global private network known as the GCI. Since 2013, the data availability (DA) requirements for IMS stations account for quality of the data, meaning that in calculation of data availability data should be exclude if: - there is no input from sensor (SHI technology); - the signal consists of constant values (SHI technology); Even more strict are requirements for the DA of the radionuclide (particulate and noble gas) stations - received data have to be analyzed, reviewed and categorized by IDC analysts. In order to satisfy the strict data and network availability requirements of the IMS Network, the operation of the facilities and the GCI are managed by IDC Operations. Operations has following main functions: - to ensure proper operation and functioning of the stations; - to ensure proper operation and functioning of the GCI; - to ensure efficient management of the stations in IDC; - to provide network oversight and incident management. At the core of the IMS Network operations are a series of tools for: monitoring the stations' state of health and data quality, troubleshooting incidents, communicating with internal and external stakeholders, and reporting. The new requirements for data availability increased the importance of the raw data quality monitoring. This task is addressed by development of additional tools for easy and fast identifying problems in data acquisition, regular activities to check compliance of the station parameters with acquired data by scheduled calibration of the seismic network, review of the samples by certified radionuclide laboratories. The DA for the networks of

  14. PRM: A database of planetary reflection matrices

    Science.gov (United States)

    Stam, D. M.; Batista, S. F. A.

    2014-04-01

    We present the PRM database with reflection matrices of various types of planets. With the matrices, users can calculate the total, and the linearly and circularly polarized fluxes of incident unpolarized light that is reflected by a planet for arbitrary illumination and viewing geometries. To allow for flexibility in these geometries, the database does not contain the elements of reflection matrices, but the coefficients of their Fourier series expansion. We describe how to sum these coefficients for given illumination and viewing geometries to obtain the local reflection matrix. The coefficients in the database can also be used to calculate flux and polarization signals of exoplanets, by integrating, for a given planetary phase angle, locally reflected fluxes across the visible part of the planetary disk. Algorithms for evaluating the summation for locally reflected fluxes, as applicable to spatially resolved observations of planets, and the subsequent integration for the disk-integrated fluxes, as applicable to spatially unresolved exoplanets are also in the database

  15. Contributing to the growth of Physical and Rehabilitation Medicine (PRM): call for a Cochrane Field in PRM.

    Science.gov (United States)

    Negrini, S; Kiekens, C; Meerpohl, J J; Thomson, D; Zampolini, M; Christodoulou, N; Delarque, A; Gutenbrunner, C; Michail, X

    2015-06-01

    The European Society of Physical and Rehabilitation Medicine (ESPRM), together with the European Journal of PRM and the PRM Section and Board of the European Union of Medical Specialists (UEMS), started an action to establish a relationship with Cochrane (formerly the Cochrane Collaboration). Cochrane is a global, independent network of researchers, professionals, patients, carers and people interested in health, with contributors from more than 130 countries. Its aim is to produce credible, accessible health information that is free from any conflicts of interest. Cochrane produces the Cochrane Library, an evidence-based resource that includes today more than 6300 Cochrane systematic reviews. Cochrane is made up of many different review groups and other entities (such as Centres and Branches), distributed around the world, that are mainly focused on specific healthcare problems (diseases, or organs). Inside Cochrane also Fields have been created, that focus on a dimension of health care other than a specific healthcare problem. A Cochrane Field represents a bridge between Cochrane and the stakeholders of the related healthcare area. The medical specialty of PRM is covering a broad medical domain: it deals with function, activities and participation in a large number of health conditions, mostly but not exclusively musculoskeletal, neurological and cardiorespiratory. Consequently, the currently more than 200 existing Cochrane Reviews are scattered among different groups. A PRM Field could greatly serve to the need of the specialty, spreading the actual Cochrane knowledge, focusing needs today not covered by Cochrane Reviews, facing the intrinsic methodological problems of the specialty. This paper introduces a call for the development of a PRM Cochrane Field, briefly reviewing what Cochrane is and how it is organized, defining the value and identifying a pathway toward the development of a PRM Cochrane Field, and finally shortly reviewing the Cochrane reviews of

  16. Membranotropic regions of the dengue virus prM protein.

    Science.gov (United States)

    Nemésio, Henrique; Villalaín, José

    2014-08-19

    The Dengue virus (DENV) prM protein consists of two moieties, the pr and M domains. Apart from preventing the premature fusion activity of the DENV E protein, prM has several other unknown biological roles, displaying both protein-protein and membrane-protein interactions. Although the prM protein is an essential component of the DENV viral cycle, little is known about its biological functions and what regions of this protein are responsible for said functions. By performing an exhaustive study of membrane rupture induced by a prM peptide library on simple and complex model membranes as well as their ability to modulate the phospholipid phase transitions of 1,2-dimyristoyl-sn-glycero-3-phosphatidylcholine and 1,2-dimyristoyl-sn-glycero-3-[phospho-rac-glycerol], we identified six membranotropic regions on the prM protein. Apart from the previously identified two transmembrane segments of the protein, one of these regions probably interacts with the fusion E protein and another one, the stem segment, would interact with the membrane modulating its structure. These data will help us understand the molecular mechanism of viral entry and morphogenesis, allow the identification of new targets for the treatment of Dengue virus infection, and make possible the future development of DENV entry inhibitors.

  17. Computer system for monitoring power boiler operation

    Energy Technology Data Exchange (ETDEWEB)

    Taler, J.; Weglowski, B.; Zima, W.; Duda, P.; Gradziel, S.; Sobota, T.; Cebula, A.; Taler, D. [Cracow University of Technology, Krakow (Poland). Inst. for Process & Power Engineering

    2008-02-15

    The computer-based boiler performance monitoring system was developed to perform thermal-hydraulic computations of the boiler working parameters in an on-line mode. Measurements of temperatures, heat flux, pressures, mass flowrates, and gas analysis data were used to perform the heat transfer analysis in the evaporator, furnace, and convection pass. A new construction technique of heat flux tubes for determining heat flux absorbed by membrane water-walls is also presented. The current paper presents the results of heat flux measurement in coal-fired steam boilers. During changes of the boiler load, the necessary natural water circulation cannot be exceeded. A rapid increase of pressure may cause fading of the boiling process in water-wall tubes, whereas a rapid decrease of pressure leads to water boiling in all elements of the boiler's evaporator - water-wall tubes and downcomers. Both cases can cause flow stagnation in the water circulation leading to pipe cracking. Two flowmeters were assembled on central downcomers, and an investigation of natural water circulation in an OP-210 boiler was carried out. On the basis of these measurements, the maximum rates of pressure change in the boiler evaporator were determined. The on-line computation of the conditions in the combustion chamber allows for real-time determination of the heat flowrate transferred to the power boiler evaporator. Furthermore, with a quantitative indication of surface cleanliness, selective sootblowing can be directed at specific problem areas. A boiler monitoring system is also incorporated to provide details of changes in boiler efficiency and operating conditions following sootblowing, so that the effects of a particular sootblowing sequence can be analysed and optimized at a later stage.

  18. Physical and rehabilitation medicine (PRM) care pathways: "spinal cord injury".

    Science.gov (United States)

    Albert, T; Beuret Blanquart, F; Le Chapelain, L; Fattal, C; Goossens, D; Rome, J; Yelnik, A P; Perrouin Verbe, B

    2012-09-01

    This document is part of a series of documents designed by the French Physical and Rehabilitation Medicine Society (SOFMER) and the French Federation of PRM (FEDMER). These documents describe the needs for or a specific type of patients; PRM care objectives, human and material resources to be implemented, chronology as well as expected outcomes. "Care pathways in PRM" is a short document designed to enable the reader (physicians, decision-maker, administrator, lawyer or finance manager) to quickly apprehend the needs of these patients and the available therapeutic care structures for proper organization and pricing of these activities. The patients after spinal cord injury are divided into five categories according to the severity of the impairments, each one being treated according to the same six parameters according to the International Classification of Functioning, Disability and Health (WHO), while taking into account personal and environmental factors that could influence the needs of these patients.

  19. Physical and rehabilitation medicine (PRM) care pathways: "stroke patients".

    Science.gov (United States)

    Yelnik, A-P; Schnitzler, A; Pradat-Diehl, P; Sengler, J; Devailly, J-P; Dehail, P; D'anjou, M-C; Rode, G

    2011-11-01

    This document is part of a series of documents designed by the French Physical and Rehabilitation Medicine Society (SOFMER) and the French Federation of PRM (FEDMER). These documents describe the needs for a specific type of patients; PRM care objectives, human and material resources to be implemented, chronology as well as expected outcomes. "Care pathways in PRM" is a short document designed to enable the reader (physicians, decision-maker, administrator, lawyer or finance manager) to quickly apprehend the needs of these patients and the available therapeutic care structures for proper organization and pricing of these activities. Stroke patients are divided into four categories according to the severity of the impairments, each one being treated according to the same six parameters according to the International Classification of Functioning, Disability and Health (WHO), while taking into account personal and environmental factors that could influence the needs of these patients.

  20. 40 CFR 60.63 - Monitoring of operations.

    Science.gov (United States)

    2010-07-01

    ...) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Standards of Performance for Portland Cement Plants § 60.63 Monitoring of operations. (a) The owner or operator of any portland cement plant subject to...

  1. Citizen Science Air Monitor (CSAM) Operating Procedures

    Science.gov (United States)

    The Citizen Science Air Monitor (CSAM) is an air monitoring system designed for measuring nitrogen dioxide (NO2) and particulate matter (PM) pollutants simultaneously. This self-contained system consists of a CairPol CairClip NO2 sensor, a Thermo Scientific personal DataRAM PM2.5...

  2. Genetic and bibliographic information: PRM2 [GenLibi

    Lifescience Database Archive (English)

    Full Text Available PRM2 protamine 2 human Asthenozoospermia (MeSH) Male Urogenital Diseases (C12) > Ge...nital Diseases, Male (C12.294) > Infertility (C12.294.365) > Infertility, Male (C12.294.365.700) > Asthenozoospermia (C12.294.365.700.253) 04A0568797 ...

  3. Differential modulation of prM cleavage, extracellular particle distribution, and virus infectivity by conserved residues at nonfurin consensus positions of the dengue virus pr-M junction.

    Science.gov (United States)

    Junjhon, Jiraphan; Lausumpao, Matthawee; Supasa, Sunpetchuda; Noisakran, Sansanee; Songjaeng, Adisak; Saraithong, Prakaimuk; Chaichoun, Kridsada; Utaipat, Utaiwan; Keelapang, Poonsook; Kanjanahaluethai, Amornrat; Puttikhunt, Chunya; Kasinrerk, Watchara; Malasit, Prida; Sittisombut, Nopporn

    2008-11-01

    In the generation of flavivirus particles, an internal cleavage of the envelope glycoprotein prM by furin is required for the acquisition of infectivity. Unlike cleavage of the prM of other flaviviruses, cleavage of dengue virus prM is incomplete in many cell lines; the partial cleavage reflects the influence of residues at furin nonconsensus positions of the pr-M junction, as flaviviruses share basic residues at positions P1, P2, and P4, recognized by furin. In this study, viruses harboring the alanine-scanning and other multiple-point mutations of the pr-M junction were generated, employing a dengue virus background that exhibited 60 to 70% prM cleavage and a preponderance of virion-sized extracellular particles. Analysis of prM and its cleavage products in viable mutants revealed a cleavage-suppressive effect at the conserved P3 Glu residue, as well as the cleavage-augmenting effects at the P5 Arg and P6 His residues, indicating an interplay between opposing modulatory influences mediated by these residues on the cleavage of the pr-M junction. Changes in the prM cleavage level were associated with altered proportions of extracellular virions and subviral particles; mutants with reduced cleavage were enriched with subviral particles and prM-containing virions, whereas the mutant with enhanced cleavage was deprived of these particles. Alterations of virus multiplication were detected in mutants with reduced prM cleavage and were correlated with their low specific infectivities. These findings define the functional roles of charged residues located adjacent to the furin consensus sequence in the cleavage of dengue virus prM and provide plausible mechanisms by which the reduction in the pr-M junction cleavability may affect virus replication.

  4. Targeted proteomics coming of age - SRM, PRM and DIA performance evaluated from a core facility perspective.

    Science.gov (United States)

    Kockmann, Tobias; Trachsel, Christian; Panse, Christian; Wahlander, Asa; Selevsek, Nathalie; Grossmann, Jonas; Wolski, Witold E; Schlapbach, Ralph

    2016-08-01

    Quantitative mass spectrometry is a rapidly evolving methodology applied in a large number of omics-type research projects. During the past years, new designs of mass spectrometers have been developed and launched as commercial systems while in parallel new data acquisition schemes and data analysis paradigms have been introduced. Core facilities provide access to such technologies, but also actively support the researchers in finding and applying the best-suited analytical approach. In order to implement a solid fundament for this decision making process, core facilities need to constantly compare and benchmark the various approaches. In this article we compare the quantitative accuracy and precision of current state of the art targeted proteomics approaches single reaction monitoring (SRM), parallel reaction monitoring (PRM) and data independent acquisition (DIA) across multiple liquid chromatography mass spectrometry (LC-MS) platforms, using a readily available commercial standard sample. All workflows are able to reproducibly generate accurate quantitative data. However, SRM and PRM workflows show higher accuracy and precision compared to DIA approaches, especially when analyzing low concentrated analytes.

  5. 40 CFR 146.13 - Operating, monitoring and reporting requirements.

    Science.gov (United States)

    2010-07-01

    ...; (iii) Periodic monitoring of the ground water quality in the first aquifer overlying the injection zone; (iv) Periodic monitoring of the ground water quality in the lowermost USDW; and (v) Any additional... Applicable to Class I Wells § 146.13 Operating, monitoring and reporting requirements. (a)...

  6. Operating experience review of an INL gas monitoring system

    Energy Technology Data Exchange (ETDEWEB)

    Cadwallader, Lee C. [Idaho National Lab. (INL), Idaho Falls, ID (United States); DeWall, K. G. [Idaho National Lab. (INL), Idaho Falls, ID (United States); Herring, J. S. [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-03-12

    This article describes the operations of several types of gas monitors in use at the Idaho National Laboratory (INL) High Temperature Electrolysis Experiment (HTE) laboratory. The gases monitored in the lab room are hydrogen, carbon monoxide, carbon dioxide, and oxygen. The operating time, calibration, and both actual and unwanted alarms are described. The calibration session time durations are described. In addition, some simple calculations are given to estimate the reliability of these monitors and the results are compared to operating experiences of other types of monitors.

  7. Differential Modulation of prM Cleavage, Extracellular Particle Distribution, and Virus Infectivity by Conserved Residues at Nonfurin Consensus Positions of the Dengue Virus pr-M Junction▿

    OpenAIRE

    Junjhon, Jiraphan; Lausumpao, Matthawee; Supasa, Sunpetchuda; Noisakran, Sansanee; Songjaeng, Adisak; Saraithong, Prakaimuk; Chaichoun, Kridsada; Utaipat, Utaiwan; Keelapang, Poonsook; Kanjanahaluethai, Amornrat; Puttikhunt, Chunya; Kasinrerk, Watchara; Malasit, Prida; Sittisombut, Nopporn

    2008-01-01

    In the generation of flavivirus particles, an internal cleavage of the envelope glycoprotein prM by furin is required for the acquisition of infectivity. Unlike cleavage of the prM of other flaviviruses, cleavage of dengue virus prM is incomplete in many cell lines; the partial cleavage reflects the influence of residues at furin nonconsensus positions of the pr-M junction, as flaviviruses share basic residues at positions P1, P2, and P4, recognized by furin. In this study, viruses harboring ...

  8. Spark PRM: Using RRTs within PRMs to efficiently explore narrow passages

    KAUST Repository

    Shi, Kensen

    2014-05-01

    © 2014 IEEE. Probabilistic RoadMaps (PRMs) have been successful for many high-dimensional motion planning problems. However, they encounter difficulties when mapping narrow passages. While many PRM sampling methods have been proposed to increase the proportion of samples within narrow passages, such difficult planning areas still pose many challenges. We introduce a novel algorithm, Spark PRM, that sparks the growth of Rapidly-expanding Random Trees (RRTs) from narrow passage samples generated by a PRM. The RRT rapidly generates further narrow passage samples, ideally until the passage is fully mapped. After reaching a terminating condition, the tree stops growing and is added to the roadmap. Spark PRM is a general method that can be applied to all PRM variants. We study the benefits of Spark PRM with a variety of sampling strategies in a wide array of environments. We show significant speedups in computation time over RRT, Sampling-based Roadmap of Trees (SRT), and various PRM variants.

  9. Operant Conditioning of Mental Retardates' Visual Monitoring.

    Science.gov (United States)

    Perryman, Roy E.; And Others

    1981-01-01

    To study improvement of visual monitoring of retardates, specialized training methods backed up by incentives were used. The extent to which these training techniques might be expected to produce results which would generalize was explored. Subjects were eight female mental retardates (ages 15-22) with IQs from 38 to 69. (Author/SJL)

  10. 40 CFR 146.23 - Operating, monitoring, and reporting requirements.

    Science.gov (United States)

    2010-07-01

    ...)); and (5) Hydrocarbon storage and enhanced recovery may be monitored on a field or project basis rather... information may be included by reference. (2) Owners or operators of hydrocarbon storage and enhanced recovery... fluid disposal operations; (ii) Monthly for enhanced recovery operations; (iii) Daily during the...

  11. Operational modes, health, and status monitoring

    Science.gov (United States)

    Taljaard, Corrie

    2016-08-01

    System Engineers must fully understand the system, its support system and operational environment to optimise the design. Operations and Support Managers must also identify the correct metrics to measure the performance and to manage the operations and support organisation. Reliability Engineering and Support Analysis provide methods to design a Support System and to optimise the Availability of a complex system. Availability modelling and Failure Analysis during the design is intended to influence the design and to develop an optimum maintenance plan for a system. The remote site locations of the SKA Telescopes place emphasis on availability, failure identification and fault isolation. This paper discusses the use of Failure Analysis and a Support Database to design a Support and Maintenance plan for the SKA Telescopes. It also describes the use of modelling to develop an availability dashboard and performance metrics.

  12. Monitoring, Operational Manager Efforts and Inventory Policy

    OpenAIRE

    Alfaro, J A; Tribó, J. (Josep)

    2003-01-01

    Operations managers are becoming more important in modern corporations. They do not only care on firms’ inventory management but also they are involved in firms’ strategic decisions. Within this setting we ask about the consequences in the inventory policy of this new role undertaken by these managers. To do so, we develop a model where a firm’s Operations Manager can devote some efforts to develop non-inventory related activities. These efforts, although non-verifiable, may be known with a c...

  13. The field of competence of the specialist in physical and rehabilitation medicine (PRM).

    Science.gov (United States)

    Gutenbrunner, C; Lemoine, F; Yelnik, A; Joseph, P-A; de Korvin, G; Neumann, V; Delarque, A

    2011-07-01

    The Field of Competence (FOC) of specialists in Physical and Rehabilitation Medicine (PRM) in Europe follows uniform basic principles described in the White Book of PRM in Europe. An agreed basis of the field of competence is the European Board curriculum for the PRM-specialist certification. However, due to national traditions, different health systems and other factors, PRM practice varies between regions and countries in Europe. Even within a country the professional practice of the individual doctor may vary because of the specific setting he or she is working in. For that reason this paper aims at a comprehensive description of the FOC in PRM. PRM specialists deal with/intervene in a wide range of diseases and functional deficits. Their interventions include, prevention of diseases and their complications, diagnosis of diseases, functional assessment, information and education of patients, families and professionals, treatments (physical modalities, drugs and other interventions). PRM interventions are often organized within PRM programmes of care. PRM interventions benefit from the involvement of PRM specialists in research. PRM specialists have knowledge of the rehabilitation process, team working, medical and physical treatments, rehabilitation technology, prevention and management of complications and methodology of research in the field. PRM specialists are involved in reducing functional consequences of many health conditions and manage functioning and disability in the respective patients. Diagnostic skills include all dimensions of body functions and structures, activities and participation issues relevant for the rehabilitation process. Additionally relevant contextual factors are assessed. PRM interventions range from medication, physical treatments, psychosocial interventions and rehabilitation technology. As PRM is based on the principles of evidence-based medicine PRM specialist are involved in research too. Quality management programs for PRM

  14. Operating Experiences of a Loss of Voltage Monitoring Program

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Eun-Chan [Korea Hydro and Nuclear Power Co. Ltd., Daejeon (Korea, Republic of)

    2015-10-15

    Loss of voltage (LOV) events continue to occur due to inadequate work management and random human errors. On February 26, 2015, regulators analyzed the root causes of LOV events and presented the results for the nuclear industry. Currently, KHNP uses a risk monitoring program, which is named 'LOV Monitor', for LOV prevention during pilot plant outages. This review introduces the operation experiences of LOV Monitor based on the evaluation results of a real event. The operation experiences of LOV Monitor in the pilot plants confirmed that this program could detect and reduce LOV possibilities from scheduling errors such as the simultaneous maintenance of energized trains and de-energized trains considering the physical conditions of the power circuit breakers. However, a maintenance culture that heeds the risk monitoring result must be strengthened in order to obtain substantial effects through applying LOV Monitor to the outage.

  15. Quantification of SAA1 and SAA2 in lung cancer plasma using the isotype-specific PRM assays.

    Science.gov (United States)

    Kim, Yeoun Jin; Gallien, Sebastien; El-Khoury, Victoria; Goswami, Panchali; Sertamo, Katriina; Schlesser, Marc; Berchem, Guy; Domon, Bruno

    2015-09-01

    The quantification of plasma proteins using the high resolution and accurate mass (HR/AM)-based parallel reaction monitoring (PRM) method provides an immediate benefit over the conventional SRM-based method in terms of selectivity. In this study, multiplexed PRM assays were developed to analyze isotypes of serum amyloid A (SAA) proteins in human plasma with a focus on SAA1 and SAA2. Elevated plasma levels of these proteins in patients diagnosed with lung cancer have been reported in previous studies. Since SAA1 and SAA2 are highly homologous, the available immunoassays tend to overestimate their concentrations due to cross-reactivity. On the other hand, when mass spectrometry (MS)-based assays are used, the presence of the several allelic variants may result in a problem of underestimation. In the present study, eight peptides that represent the target proteins at three different levels: isotype-specific (SAA1α,  SAA 1β,  SAA1γ,  SAA2α,  SAA2β), protein-specific (SAA1 or SAA2), and pan SAA (SAA1 and SAA2) were chosen to differentiate SAAs in lung cancer plasma samples using a panel of PRM assays. The measurement of specific isotypes, leveraging the analytical performance of PRM, allowed to quantify the allelic variants of both target proteins. The isotypes detected were corroborated with the genetic information obtained from the same samples. The combination of SAA2α and SAA2β assays representing the total SAA2 concentration demonstrated a superior analytical outcome than the previously used assay on the common peptide when applied to the detection of lung cancer.

  16. Using participatory risk mapping (PRM) to identify and understand people's perceptions of crop loss to animals in Uganda.

    Science.gov (United States)

    Webber, Amanda D; Hill, Catherine M

    2014-01-01

    Considering how people perceive risks to their livelihoods from local wildlife is central to (i) understanding the impact of crop damage by animals on local people and (ii) recognising how this influences their interactions with, and attitudes towards, wildlife. Participatory risk mapping (PRM) is a simple, analytical tool that can be used to identify and classify risk within communities. Here we use it to explore local people's perceptions of crop damage by wildlife and the animal species involved. Interviews (n = 93, n = 76) and seven focus groups were conducted in four villages around Budongo Forest Reserve, Uganda during 2004 and 2005. Farms (N = 129) were simultaneously monitored for crop loss. Farmers identified damage by wildlife as the most significant risk to their crops; risk maps highlighted its anomalous status compared to other anticipated challenges to agricultural production. PRM was further used to explore farmers' perceptions of animal species causing crop damage and the results of this analysis compared with measured crop losses. Baboons (Papio anubis) were considered the most problematic species locally but measurements of loss indicate this perceived severity was disproportionately high. In contrast goats (Capra hircus) were considered only a moderate risk, yet risk of damage by this species was significant. Surprisingly, for wild pigs (Potamochoerus sp), perceptions of severity were not as high as damage incurred might have predicted, although perceived incidence was greater than recorded frequency of damage events. PRM can assist researchers and practitioners to identify and explore perceptions of the risk of crop damage by wildlife. As this study highlights, simply quantifying crop loss does not determine issues that are important to local people nor the complex relationships between perceived risk factors. Furthermore, as PRM is easily transferable it may contribute to the identification and development of standardised approaches

  17. Position paper on PRM and persons with long term disabilities.

    Science.gov (United States)

    Takáč, P; Petrovičová, J; Delarque, A; Stibrant Sunnerhagen, K; Neumann, V; Vetra, A; Berteanu, M; Christodoulou, N

    2014-08-01

    In the current population we observe a rise of chronic health problems often with multiple characteristics. This results in a growing number of people who are experiencing long-term disabilities or difficulties in functioning because of disability. These conditions require a complex response over an extended period of time, that involves coordinated inputs from a wide range of health professionals. This paper argues the central role and benefit of rehabilitation and describes the rehabilitation as an integral component in the management of people with chronic disabilities. It also presents the most important related definitions: long-term care, rehabilitation for chronic disease and disability, the aim of physical and rehabilitation medicine (PRM). An interdisciplinary team is ideal for an effective implementation of rehabilitation for chronic disease and disability. However, the article mainly focuses on defining the role and contribution of the PRM physician in the rehabilitation of persons with long-term disabilities. The article includes: descriptions of his/her key role and competencies, particularly with regard to medical and functional status and prognosis, of the ability to comprehensively define the rehabilitation needs of the patient/person with respect to ICD-WHO classification domains, of the cooperation with other medical specialists and health professionals, of determining the rehabilitation potential, of developing the rehabilitation plan tailored to specific needs, as well as of the contribution of PRM physician in the follow-up care pathways.

  18. Operator coil monitoring Acceptance Test Procedure

    Energy Technology Data Exchange (ETDEWEB)

    Erhart, M.F.

    1995-05-16

    The readiness of the Data Acquisition and Control System (DACS) to provide monitoring and control of the Programmable Logic Controller (PLC) abort coils from the Master and RSS stations will be systematically tested during performance of this procedure. It should be noted that these are not physical abort coils but software coils controlled by the software`s ladder logic. The readiness of the DACS to properly interface with the ENRAF wire level gauge installed in the SY-101 storage tank will also be tested. During this test, a verification of all abort coil indications will be conducted at the DACS Development Facility in the 306E Building by injecting an input signal for each DACS sensor that has an associated abort coil until the abort coil actuates, and then ensuring that the status of the abort coil indicated at the Master and RSS stations is correct. Each abort coil will also be tested to ensure that the ``ENABLE`` and ``DISABLE`` controls from the Master and RSS stations function correctly, and only with the use of proper passwords.

  19. PRM:A Resource Management Framework for Policy-driven QoS Control in Enhanced Internets

    Institute of Scientific and Technical Information of China (English)

    FU Xiaoming; ZHANG Yaoxue

    2001-01-01

    The Internet has evolved from a tra-ditional best-effort delivery data network into an en-hanced Internet that can provide a certain Qualityof Service(QoS) mechanisms for applications.How-ever,these QoS mechanisms usually do not take policyfactors into account such as priority and time-of-day.The paper presents a Resource Management Frame-work for Policy-driven QoS control (PRM) in en-hanced internets,which consists of four components:Domain Policy Controller(DPC) resides an adminis-trator domain,Border Resource Manager(BRM) re-sides between adjacent domains,Interior ResourceManagers(IRM) in each router between two BRMswithin the same domain,and Endsystem ResourceManager(ERM) in charge of end-node/host router re-sources.We first introduce challenges and demandsfacing the enhanced internets,then give a formalizeddefinition of policy and describe the functions and in-teraction of components of PRM.Specifically we takeQoS-pricing policy used in a Diff-Serv environmentas an example to illustrate the operational phases of PRM.

  20. General Operational Procedure for Pedestrian Radiation Portal Monitors

    Energy Technology Data Exchange (ETDEWEB)

    Belooussov, Andrei V. [Los Alamos National Laboratory

    2012-08-08

    This document outlines the basic conduct of operation (CONOPS) for a pedestrian radiation portal monitor (RPM), provided that the CONOPS is not facility or RPM specific and that it is based on a general understanding of a pedestrian RPM operation. The described CONOPS for a pedestrian RPM is defined by: (1) RPM design and operational characteristics, (2) type of pedestrian traffic, and (3) goal for RPM installation. Pedestrian RPMs normally are deployed for the continuous monitoring of individuals passing through point of control to detect the unauthorized traffic of radioactive/nuclear materials. RPMs generally are designed to detect gamma- and neutron-emitting materials.

  1. Monitoring operational data production applying Big Data tooling

    Science.gov (United States)

    Som de Cerff, Wim; de Jong, Hotze; van den Berg, Roy; Bos, Jeroen; Oosterhoff, Rijk; Klein Ikkink, Henk Jan; Haga, Femke; Elsten, Tom; Verhoef, Hans; Koutek, Michal; van de Vegte, John

    2015-04-01

    Within the KNMI Deltaplan programme for improving the KNMI operational infrastructure an new fully automated system for monitoring the KNMI operational data production systems is being developed: PRISMA (PRocessflow Infrastructure Surveillance and Monitoring Application). Currently the KNMI operational (24/7) production systems consist of over 60 applications, running on different hardware systems and platforms. They are interlinked for the production of numerous data products, which are delivered to internal and external customers. All applications are individually monitored by different applications, complicating root cause and impact analysis. Also, the underlying hardware and network is monitored separately using Zabbix. Goal of the new system is to enable production chain monitoring, which enables root cause analysis (what is the root cause of the disruption) and impact analysis (what other products will be effected). The PRISMA system will make it possible to dispose all the existing monitoring applications, providing one interface for monitoring the data production. For modeling the production chain, the Neo4j Graph database is used to store and query the model. The model can be edited through the PRISMA web interface, but is mainly automatically provided by the applications and systems which are to be monitored. The graph enables us to do root case and impact analysis. The graph can be visualized in the PRISMA web interface on different levels. Each 'monitored object' in the model will have a status (OK, error, warning, unknown). This status is derived by combing all log information available. For collecting and querying the log information Splunk is used. The system is developed using Scrum, by a multi-disciplinary team consisting of analysts, developers, a tester and interaction designer. In the presentation we will focus on the lessons learned working with the 'Big data' tooling Splunk and Neo4J.

  2. Hydrogen and Oxygen Gas Monitoring System Design and Operation

    Energy Technology Data Exchange (ETDEWEB)

    Lee C. Cadwallader; Kevin G. DeWall; J. Stephen Herring

    2007-06-01

    This paper describes pertinent design practices of selecting types of monitors, monitor unit placement, setpoint selection, and maintenance considerations for gas monitors. While hydrogen gas monitors and enriched oxygen atmosphere monitors as they would be needed for hydrogen production experiments are the primary focus of this paper, monitors for carbon monoxide and carbon dioxide are also discussed. The experiences of designing, installing, and calibrating gas monitors for a laboratory where experiments in support of the DOE Nuclear Hydrogen Initiative (NHI) are described along with codes, standards, and regulations for these monitors. Information from the literature about best operating practices is also presented. The NHI program has two types of activities. The first, near-term activity is laboratory and pilot-plant experimentation with different processes in the kilogram per day scale to select the most promising types of processes for future applications of hydrogen production. Prudent design calls for indoor gas monitors to sense any hydrogen leaks within these laboratory rooms. The second, longer-term activity is the prototype, or large-scale plants to produce tons of hydrogen per day. These large, outdoor production plants will require area (or “fencepost”) monitoring of hydrogen gas leaks. Some processes will have oxygen production with hydrogen production, and any oxygen releases are also safety concerns since oxygen gas is the strongest oxidizer. Monitoring of these gases is important for personnel safety of both indoor and outdoor experiments. There is some guidance available about proper placement of monitors. The fixed point, stationary monitor can only function if the intruding gas contacts the monitor. Therefore, monitor placement is vital to proper monitoring of the room or area. Factors in sensor location selection include: indoor or outdoor site, the location and nature of potential vapor/gas sources, chemical and physical data of the

  3. RadMonitor: radiology operations data mining in real time.

    Science.gov (United States)

    Chen, Richard; Mongkolwat, Pattanasak; Channin, David S

    2008-09-01

    This paper describes the web-based visualization interface of RadMonitor, a platform-independent web application designed to help manage the complexity of information flow within a health care enterprise. The system eavesdrops on Health Layer 7 traffic and parses statistical operational information into a database. The information is then presented to the user as a treemap--a graphical visualization scheme that simplifies the display of hierarchical information. While RadMonitor has been implemented for the purpose of analyzing radiology operations, its XML backend allows it to be reused for virtually any other hierarchical data set.

  4. Lazy Toggle PRM: A single-query approach to motion planning

    KAUST Repository

    Denny, Jory

    2013-05-01

    Probabilistic RoadMaps (PRMs) are quite suc-cessful in solving complex and high-dimensional motion plan-ning problems. While particularly suited for multiple-query scenarios and expansive spaces, they lack efficiency in both solving single-query scenarios and mapping narrow spaces. Two PRM variants separately tackle these gaps. Lazy PRM reduces the computational cost of roadmap construction for single-query scenarios by delaying roadmap validation until query time. Toggle PRM is well suited for mapping narrow spaces by mapping both Cfree and Cobst, which gives certain theoretical benefits. However, fully validating the two resulting roadmaps can be costly. We present a strategy, Lazy Toggle PRM, for integrating these two approaches into a method which is both suited for narrow passages and efficient single-query calculations. This simultaneously addresses two challenges of PRMs. Like Lazy PRM, Lazy Toggle PRM delays validation of roadmaps until query time, but if no path is found, the algorithm augments the roadmap using the Toggle PRM methodology. We demonstrate the effectiveness of Lazy Toggle PRM in a wide range of scenarios, including those with narrow passages and high descriptive complexity (e.g., those described by many triangles), concluding that it is more effective than existing methods in solving difficult queries. © 2013 IEEE.

  5. Monoclonal Antibodies for Dengue Virus prM Glycoprotein Protect Mice against Lethal Dengue Infection

    Science.gov (United States)

    1989-09-15

    Nile virus and a prelysozomal endosome prM glycoprotein of dengue virus can also be required for viral replication . PrM Mabs 2H2 protective against...tech- bodies can prevent lethal alphavirus encepha- niques to preserve immunogenicity, to deter- litis. Nature 297: 70-72. UI:82173237 mine whether

  6. Monitoring noise from aircraft operations in the vicinity of airports

    Science.gov (United States)

    Eldred, Kenneth Mck.

    This paper presents an overview of a proposed Society of Automotive Engineers Aerospace Recommended Practice (ARP4721) with this title. The ARP is intended to provide engineering methods for measuring the noise from aircraft operations in the vicinity of airports for a variety of potential users and purposes. It uses the A-weighted Sound Level (Slow) and quantities derived from its time history as the principal descriptor of aircraft noise. It represents an evolutionary growth from the airport noise monitoring experience over the past three decades. It is intended to cover both unattended multi-channel noise measurement systems used for routine monitoring and attended systems used for special monitoring or for other measurement purposes. It contains recommended methods for the acquisition of non-acoustical data and requirements for systems that acquire acoustical data and their processing. It provides information on temporal and spatial sampling with respect to sampling design and errors, and discusses several applications for its use in monitoring.

  7. An Autonomous Long Range Monitoring System For Emergency Operators

    CERN Document Server

    Lanati, Matteo; Secco, Emanuele Lindo; Magenes, Giovanni; Gamba, Paolo

    2011-01-01

    Miniaturization and portability of new electronics lead up to wearable devices embedded within garments: a European program called ProeTEX developed multi-purpose sensors integrated within emergency operators' garments in order to monitor their health state and the surrounding environment. This work deals with the development of an autonomous Long Range communication System (LRS), suitable to transmit data between operators' equipment and the local command post, where remote monitoring software is set up. The LRS infrastructure is based on Wi-Fi protocol and modular architecture. Field tests carried out on the developed prototype showed a high reliability in terms of correctly exchanged data and recovering capabilities in case of temporary disconnection, due to the operator's movements.

  8. GNSS-based operational monitoring devices for forest logging operation chains

    Directory of Open Access Journals (Sweden)

    Raimondo Gallo

    2013-09-01

    Full Text Available The first results of a new approach for implementing operational monitoring tool to control the performance of forest mechanisation chains are proposed and discussed. The solution is based on Global Navigation Satellite System (GNSS tools that are the core of a datalogging system that, in combination with a specific inference-engine, is able to analyse process times, work distances, forward speeds, vehicle tracking and number of working cycles in forest operations. As a consequence the operational monitoring control methods could provide an evaluation of the efficiency of the investigated forest operations. The study has monitored the performance of a tower yarder with crane and processor-head, during logging operations. The field surveys consisted on the installation of the GNSS device directly on the forest equipment for monitoring its movements. Simultaneously the field survey considered the integration of the GNSS information with a time study of work elements based on the continuous time methods supported by a time study board. Additionally, where possible, the onboard computer of the forest machine was also used in order to obtain additional information to be integrated to the GNSS data and the time study. All the recorded GNSS data integrated with the work elements study were thus post-processed through GIS analysis. The preliminary overview about the application of this approach on harvesting operations has permitted to assess a good feasibility of the use of GNSS in the relief of operative times in high mechanised forest chains. Results showed an easy and complete identification of the different operative cycles and elementary operations phases, with a maximum difference between the two methodologies of 10.32%. The use of GNSS installed on forest equipment, integrated with the inferenceengine and also with an interface for data communication or data storage, will permit an automatic or semi-automatic operational monitoring, improving

  9. Managed PACS operation with an automatic monitoring tool

    Science.gov (United States)

    Zhang, Jianguo; Han, Ruolin; Wu, Dongqing; Zhang, Xiaoyan; Zhuang, Jun; Feng, Jie; Wang, Mingpeng; Zhang, Guozhen; Wang, Cuanfu

    2002-05-01

    Huadong hospital in Shanghai with 800 beds provides health care services for inpatients and outpatients, as well as special senior and VIP patients. In order to move to digital imaging based radiology practice, and also provide better intra-hospital consultation services for senior and VIP patients, we started to implement PACS for hospital wide services from 1999, and also designed and developed an automatic monitoring system (AMS) to monitor and control PACS operation and dataflow to decrease the total cost of ownership for PACS operation. We installed the AMS on top of the Huadong Hospital PACS in the May of 2001. The installation was painless, did not interrupt the normal PACS operation, and took only one month. The PACS administrators with the AMS can now monitor and control the entire PACS operation in real time, and also track patient and image data flow automatically. These features make administrators take proper action even before user's complaint if any failure happened in any PACS component or process, they reduce the size of the management team, and decrease total cost of PACS ownership.

  10. Prototyping an Operational System with Multiple Sensors for Pasture Monitoring

    Directory of Open Access Journals (Sweden)

    Tim Wark

    2013-07-01

    Full Text Available Combining multiple proximal sensors within a wireless sensor network (WSN enhances our capacity to monitor vegetation, compared to using a single sensor or non-networked setup. Data from sensors with different spatial and temporal characteristics can provide complementary information. For example, point-based sensors such as multispectral sensors which monitor at high temporal frequency but, at a single point, can be complemented by array-based sensors such as digital cameras which have greater spatial resolution but may only gather data at infrequent intervals. In this article we describe the successful deployment of a prototype system for using multiple proximal sensors (multispectral sensors and digital cameras for monitoring pastures. We show that there are many technical issues involved in such a deployment, and we share insights relevant for other researchers who may consider using WSNs for an operational deployment for pasture monitoring under often difficult environmental conditions. Although the sensors and infrastructure are important, we found that other issues arise and that an end-to-end workflow is an essential part of effectively capturing, processing and managing the data from a WSN. Our deployment highlights the importance of testing and ongoing monitoring of the entire workflow to ensure the quality of data captured. We demonstrate that the combination of different sensors enhances our ability to identify sensor problems necessary to collect accurate data for pasture monitoring.

  11. Studies on the Painlev\\'e Equations, V, \\\\ Third Painlev\\'e Equations \\\\ of Special Type $P_{\\rm III}(D_7)$ and $P_{\\rm III}(D_8)$

    OpenAIRE

    Ohyama, Yousuke; Kwamuko, Hiroyuki; Sakai, Hidetaka; Okamoto, Kazuo

    2006-01-01

    By means of geometrical classification (\\cite{S}) of space of initial conditions, it is natural to consider the three types, $P_{\\rm III}(D_6)$, $P_{\\rm III}(D_7)$ and $P_{\\rm III}(D_8)$, for the third Painlev\\'e equation. The fourth article of the series of papers \\cite{O2} on the Painlev\\'e equations is concerned with $P_{\\rm III}(D_6)$, generic type of the equation. The other two types, $P_{\\rm III}(D_7)$ and $P_{\\rm III}(D_8)$ are obtained as degeneration from $P_{\\rm III}(D_6...

  12. Operational monitoring of turbidity in rivers: how satellites can contribute

    Science.gov (United States)

    Hucke, Dorothee; Hillebrand, Gudrun; Winterscheid, Axel; Kranz, Susanne; Baschek, Björn

    2016-10-01

    The applications of remote sensing in hydrology are diverse and offer significant benefits for water monitoring. Up to now, operational river monitoring and sediment management in Germany mainly rely on in-situ measurements and on results obtained from numerical modelling. Remote sensing by satellites has a great potential to supplement existing data with two-dimensional information on near-surface turbidity distributions at greater spatial scales than in-situ measurements can offer. Within the project WasMon-CT (WaterMonitoring-Chlorophyll/Turbidity), the Federal Institute of Hydrology (BfG) aims at the implementation of an operational monitoring of turbidity distributions based on satellite images (esp. Sentinel-2, Landsat7 and 8). Initially, selected federal inland and estuarine waterways will be addressed: Rhine, Elbe, Ems, Weser. WasMon-CT is funded within the German Copernicus activities. Within the project, a database of atmospherically corrected, geo-referenced turbidity data will be assembled. The collected corresponding meta-data will include aspects of satellite data as well as hydrological data, e.g. cloud cover and river run-off. Based on this catalogue of spatially linked meta-data, the satellite data will be selected by e.g. cloud cover or run-off. The permanently updated database will include past as well as recent satellite images. It is designed with a long-term perspective to optimize the existing in-situ measurement network, which will serve partly for calibration and partly as validation data set. The aim is to extend, but not to substitute, the existing frequent point measurements with spatially extensive, satellite-derived data from the near surface part of the water column. Here, turbidity is used as proxy for corresponding suspended sediment concentrations. For this, the relationship between turbidity and suspended sediment concentrations will be investigated. Products as e.g. longitudinal profiles or virtual measurement stations will be

  13. Airborne Transducer Integrity under Operational Environment for Structural Health Monitoring

    Directory of Open Access Journals (Sweden)

    Mohammad Saleh Salmanpour

    2016-12-01

    Full Text Available This paper investigates the robustness of permanently mounted transducers used in airborne structural health monitoring systems, when exposed to the operational environment. Typical airliners operate in a range of conditions, hence, structural health monitoring (SHM transducer robustness and integrity must be demonstrated for these environments. A set of extreme temperature, altitude and vibration environment test profiles are developed using the existing Radio Technical Commission for Aeronautics (RTCA/DO-160 test methods. Commercially available transducers and manufactured versions bonded to carbon fibre reinforced polymer (CFRP composite materials are tested. It was found that the DuraAct transducer is robust to environmental conditions tested, while the other transducer types degrade under the same conditions.

  14. Assessment model of dam operation risk based on monitoring data

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Although the dams produce remarkable social and economic benefits,the threat made by unsafe dams to the life and property of people who live in the lower river area is un-negligible.Based on the monitoring data which reflect the safety condition of dams,the risk degree concept is proposed and the analysis system and model for evaluating risk degree (rate) are established in this paper by combining the reliability theory and field monitoring data.The analysis method for risk degree is presented based on Bayesian approach.A five-grade risk degree system for dam operation risk and corresponding risk degree is put forward according to the safety condition of dams.The operation risks of four cascade dams on some river are analyzed by the model and approach presented here and the result is adopted by the owner.

  15. ATLAS trigger operations: Monitoring with ``Xmon'' rate prediction system

    Science.gov (United States)

    Aukerman, Andrew; Hong, Tae Min

    2017-01-01

    We present the operations and online monitoring with the ``Xmon'' rate prediction system for the trigger system at the ATLAS Experiment. A two-level trigger system reduces the LHC's bunch-crossing rate, 40 MHz at design capacity, to an average recording rate of about 1 kHz, while maintaining a high efficiency of selecting events of interest. The Xmon system uses the luminosity value to predict trigger rates that are, in turn, compared with incoming rates. The predictions rely on past runs to parameterize the luminosity dependency of the event rate for a trigger algorithm. Some examples are given to illustrate the performance of the tool during recent operations.

  16. Toggle PRM: A Coordinated Mapping of C-Free and C-Obstacle in Arbitrary Dimension

    KAUST Repository

    Denny, Jory

    2013-01-01

    Motion planning has received much attention over the past 40 years. More than 15 years have passed since the introduction of the successful sampling-based approach known as the Probabilistic RoadMap Method (PRM). PRM and its many variants have demonstrated great success for some high-dimensional problems, but they all have some level of difficulty in the presence of narrow passages. Recently, an approach called Toggle PRM has been introduced whose performance does not degrade for 2-dimensional problems with narrow passages. In Toggle PRM, a simultaneous, coordinated mapping of both C free and C obst is performed and every connection attempt augments one of the maps – either validating an edge in the current space or adding a configuration ’witnessing’ the connection failure to the other space. In this paper, we generalize Toggle PRM to d-dimensions and show that the benefits of mapping both C free and C obst continue to hold in higher dimensions. In particular, we introduce a new narrow passage characterization, α-ε-separable narrow passages, which describes the types of passages that can be successfully mapped by Toggle PRM. Intuitively, α-ε-separable narrow passages are arbitrarily narrow regions of C free that separate regions of C obst , at least locally, such as hallways in an office building. We experimentally compare Toggle PRM with other methods in a variety of scenarios with different types of narrow passages and robots with up to 16 dof.

  17. Transposon insertion reveals pRM, a plasmid of Rickettsia monacensis.

    Science.gov (United States)

    Baldridge, Gerald D; Burkhardt, Nicole Y; Felsheim, Roderick F; Kurtti, Timothy J; Munderloh, Ulrike G

    2007-08-01

    Until the recent discovery of pRF in Rickettsia felis, the obligate intracellular bacteria of the genus Rickettsia (Rickettsiales: Rickettsiaceae) were thought not to possess plasmids. We describe pRM, a plasmid from Rickettsia monacensis, which was detected by pulsed-field gel electrophoresis and Southern blot analyses of DNA from two independent R. monacensis populations transformed by transposon-mediated insertion of coupled green fluorescent protein and chloramphenicol acetyltransferase marker genes into pRM. Two-dimensional electrophoresis showed that pRM was present in rickettsial cells as circular and linear isomers. The 23,486-nucleotide (31.8% G/C) pRM plasmid was cloned from the transformant populations by chloramphenicol marker rescue of restriction enzyme-digested transformant DNA fragments and PCR using primers derived from sequences of overlapping restriction fragments. The plasmid was sequenced. Based on BLAST searches of the GenBank database, pRM contained 23 predicted genes or pseudogenes and was remarkably similar to the larger pRF plasmid. Two of the 23 genes were unique to pRM and pRF among sequenced rickettsial genomes, and 4 of the genes shared by pRM and pRF were otherwise found only on chromosomes of R. felis or the ancestral group rickettsiae R. bellii and R. canadensis. We obtained pulsed-field gel electrophoresis and Southern blot evidence for a plasmid in R. amblyommii isolate WB-8-2 that contained genes conserved between pRM and pRF. The pRM plasmid may provide a basis for the development of a rickettsial transformation vector.

  18. Verification of operating software for cooperative monitoring applications

    Energy Technology Data Exchange (ETDEWEB)

    Tolk, K.M.; Rembold, R.K.

    1997-08-01

    Monitoring agencies often use computer based equipment to control instruments and to collect data at sites that are being monitored under international safeguards or other cooperative monitoring agreements. In order for this data to be used as an independent verification of data supplied by the host at the facility, the software used must be trusted by the monitoring agency. The monitoring party must be sure that the software has not be altered to give results that could lead to erroneous conclusions about nuclear materials inventories or other operating conditions at the site. The host might also want to verify that the software being used is the software that has been previously inspected in order to be assured that only data that is allowed under the agreement is being collected. A description of a method to provide this verification using keyed has functions and how the proposed method overcomes possible vulnerabilities in methods currently in use such as loading the software from trusted disks is presented. The use of public key data authentication for this purpose is also discussed.

  19. Generation and Characterization of a Monoclonal Antibody Against prM Protein of West Nile Virus

    OpenAIRE

    Guo, Li-Ping; Huo, Hong; Wang, Xiao-Lei; Bu, Zhi-Gao; Hua, Rong-Hong

    2014-01-01

    West Nile virus (WNV), which is an emerging pathogenic flavivirus with increasing distribution worldwide, is the cause of major human and animal health concerns. The pre-membrane (prM) protein of WNV is cleaved during maturation by the furin protease into the structural protein M and a pr-segment. In this study we generated and characterized a monoclonal antibody (MAb) against the WNV prM protein. Western blot analysis showed that the MAb reacted with WNV prM specifically. Immunohistochemistr...

  20. International Society of Physical and Rehabilitation Medicine (ISPRM):strengthening Physical and Rehabilitation Medicine (PRM) worldwide

    Institute of Scientific and Technical Information of China (English)

    Gerold Stucki; Jan D.Reinhardt; Marta Imamura; Jianan Li; Joel A.De Lisa

    2011-01-01

    @@ Physiral and Rehabilitation Medicine (PRM) is the Medicine of Functioning in light of health conditions, under consideration of the person and in interaction with the environment[1-2].PRM focuses on the application of rehabilitation, the third health strategy which complements the preventive and curative health strategies.Thanks to the increasing survival of people after injury and formerly conditions as well as aging populations and an associated increase in chronic conditions, PRM as the leader of the rehabilitation will, over the next decades, assume an ever more important role in the health care systems worldwide.

  1. Federal Radiological Monitoring and Assessment Center Monitoring Manual Volume 1, Operations

    Energy Technology Data Exchange (ETDEWEB)

    NSTec Aerial Measurement Systems

    2012-07-31

    The Monitoring division is primarily responsible for the coordination and direction of: Aerial measurements to delineate the footprint of radioactive contaminants that have been released into the environment. Monitoring of radiation levels in the environment; Sampling to determine the extent of contaminant deposition in soil, water, air and on vegetation; Preliminary field analyses to quantify soil concentrations or depositions; and Environmental and personal dosimetry for FRMAC field personnel, during a Consequence Management Response Team (CMRT) and Federal Radiological Monitoring and Assessment Center (FRMAC) response. Monitoring and sampling techniques used during CM/FRMAC operations are specifically selected for use during radiological emergencies where large numbers of measurements and samples must be acquired, analyzed, and interpreted in the shortest amount of time possible. In addition, techniques and procedures are flexible so that they can be used during a variety of different scenarios; e.g., accidents involving releases from nuclear reactors, contamination by nuclear waste, nuclear weapon accidents, space vehicle reentries, or contamination from a radiological dispersal device. The Monitoring division also provides technicians to support specific Health and Safety Division activities including: The operation of the Hotline; FRMAC facility surveys; Assistance with Health and Safety at Check Points; and Assistance at population assembly areas which require support from the FRMAC. This volume covers deployment activities, initial FRMAC activities, development and implementation of the monitoring and assessment plan, the briefing of field teams, and the transfer of FRMAC to the EPA.

  2. Real-Time Distributed Embedded Oscillator Operating Frequency Monitoring

    Science.gov (United States)

    Pollock, Julie; Oliver, Brett; Brickner, Christopher

    2012-01-01

    A document discusses the utilization of embedded clocks inside of operating network data links as an auxiliary clock source to satisfy local oscillator monitoring requirements. Modem network interfaces, typically serial network links, often contain embedded clocking information of very tight precision to recover data from the link. This embedded clocking data can be utilized by the receiving device to monitor the local oscillator for tolerance to required specifications, often important in high-integrity fault-tolerant applications. A device can utilize a received embedded clock to determine if the local or the remote device is out of tolerance by using a single link. The local device can determine if it is failing, assuming a single fault model, with two or more active links. Network fabric components, containing many operational links, can potentially determine faulty remote or local devices in the presence of multiple faults. Two methods of implementation are described. In one method, a recovered clock can be directly used to monitor the local clock as a direct replacement of an external local oscillator. This scheme is consistent with a general clock monitoring function whereby clock sources are clocking two counters and compared over a fixed interval of time. In another method, overflow/underflow conditions can be used to detect clock relationships for monitoring. These network interfaces often provide clock compensation circuitry to allow data to be transferred from the received (network) clock domain to the internal clock domain. This circuit could be modified to detect overflow/underflow conditions of the buffering required and report a fast or slow receive clock, respectively.

  3. Sensors and OBIA synergy for operational monitoring of surface water

    Science.gov (United States)

    Masson, Eric; Thenard, Lucas

    2010-05-01

    This contribution will focus on combining Object Based Image Analysis (i.e. OBIA with e-Cognition 8) and recent sensors (i.e. Spot 5 XS, Pan and ALOS Prism, Avnir2, Palsar) to address the technical feasibility for an operational monitoring of surface water. Three cases of river meandering (India), flood mapping (Nepal) and dam's seasonal water level monitoring (Morocco) using recent sensors will present various application of surface water monitoring. The operational aspect will be demonstrated either by sensor properties (i.e. spatial resolution and bandwidth), data acquisition properties (i.e. multi sensor, return period and near real-time acquisition) but also with OBIA algorithms (i.e. fusion of multi sensors / multi resolution data and batch processes). In the first case of river meandering (India) we will address multi sensor and multi date satellite acquisition to monitor the river bed mobility within a floodplain using an ALOS dataset. It will demonstrate the possibility of an operational monitoring system that helps the geomorphologist in the analysis of fluvial dynamic and sediment budget for high energy rivers. In the second case of flood mapping (Nepal) we will address near real time Palsar data acquisition at high spatial resolution to monitor and to map a flood extension. This ALOS sensor takes benefit both from SAR and L band properties (i.e. atmospheric transparency, day/night acquisition, low sensibility to surface wind). It's a real achievement compared to optical imagery or even other high resolution SAR properties (i.e. acquisition swath, bandwidth and data price). These advantages meet the operational needs set by crisis management of hydrological disasters but also for the implementation of flood risk management plans. The last case of dam surface water monitoring (Morocco) will address an important issue of water resource management in countries affected by water scarcity. In such countries water users have to cope with over exploitation

  4. Monitoring data transfer latency in CMS computing operations

    CERN Document Server

    Bonacorsi, D; Magini, N; Sartirana, A; Taze, M; Wildish, T

    2015-01-01

    During the first LHC run, the CMS experiment collected tens of Petabytes of collision and simulated data, which need to be distributed among dozens of computing centres with low latency in order to make efficient use of the resources. While the desired level of throughput has been successfully achieved, it is still common to observe transfer workflows that cannot reach full completion in a timely manner due to a small fraction of stuck files which require operator intervention.For this reason, in 2012 the CMS transfer management system, PhEDEx, was instrumented with a monitoring system to measure file transfer latencies, and to predict the completion time for the transfer of a data set. The operators can detect abnormal patterns in transfer latencies while the transfer is still in progress, and monitor the long-term performance of the transfer infrastructure to plan the data placement strategy.Based on the data collected for one year with the latency monitoring system, we present a study on the different fact...

  5. Operational Surface Water Detection and Monitoring Using Radarsat 2

    Directory of Open Access Journals (Sweden)

    Sandra Bolanos

    2016-03-01

    Full Text Available Traditional on-site methods for mapping and monitoring surface water extent are prohibitively expensive at a national scale within Canada. Despite successful cost-sharing programs between the provinces and the federal government, an extensive number of water features within the country remain unmonitored. Particularly difficult to monitor are the potholes in the Canadian Prairie region, most of which are ephemeral in nature and represent a discontinuous flow that influences water pathways, runoff response, flooding and local weather. Radarsat-2 and the Radarsat Constellation Mission (RCM offer unique capabilities to map the extent of water bodies at a national scale, including unmonitored sites, and leverage the current infrastructure of the Meteorological Service of Canada to monitor water information in remote regions. An analysis of the technical requirements of the Radarsat-2 beam mode, polarization and resolution is presented. A threshold-based procedure to map locations of non-vegetated water bodies after the ice break-up is used and complemented with a texture-based indicator to capture the most homogeneous water areas and automatically delineate their extents. Some strategies to cope with the radiometric artifacts of noise inherent to Synthetic Aperture Radar (SAR images are also discussed. Our results show that Radarsat-2 Fine mode can capture 88% of the total water area in a fully automated way. This will greatly improve current operational procedures for surface water monitoring information and impact a number of applications including weather forecasting, hydrological modeling, and drought/flood predictions.

  6. Westinghouse Hanford Company operational environmental monitoring annual report, CY 1992

    Energy Technology Data Exchange (ETDEWEB)

    Schmidt, J.W.; Johnson, A.R.; McKinney, S.M.; Perkins, C.J.

    1993-07-01

    This document presents the results of the Westinghouse Hanford Company near-facility operational environmental monitoring for 1992 in the 100, 200/600, and 300/400 Areas of the Hanford Site, in south-central Washington State in 1992. Surveillance activities included sampling and analyses of ambient air, surface water, groundwater, sediments, soil, and biota. Also, external radiation measurements and radiological surveys were taken at waste disposal sites, radiologically controlled areas, and roads. These activities were conducted to assess and to control the impacts of nuclear facilities and waste sites on the workers and the local environment. Additionally, diffuse sources were monitored to determine compliance with Federal, State, and/or local regulations. In general, although impacts from nuclear facilities are still seen on the Hanford Site and are slightly elevated when compared to offsite, these impacts are less than in previous years.

  7. Dengue Patients Exhibit Higher Levels of PrM and E Antibodies Than Their Asymptomatic Counterparts

    OpenAIRE

    Adeline Syin Lian Yeo; Anusyah Rathakrishnan; Seok Mui Wang; Sasheela Ponnampalavanar; Rishya Manikam; Jameela Sathar; Santha Kumari Natkunam; Shamala Devi Sekaran

    2015-01-01

    Dengue virus infection is a common tropical disease which often occurs without being detected. These asymptomatic cases provide information in relation to the manifestation of immunological aspects. In this study, we developed an ELISA method to compare neutralizing effects of dengue prM and E antibodies between dengue patients and their asymptomatic household members. Recombinant D2 premembrane (prM) was constructed, cloned, and tested for antigenicity. The recombinant protein was purified a...

  8. [Immunochemical properties of West Nile virus protein prM and protein M C-end].

    Science.gov (United States)

    Bogachek, M V; Protopopova, E V; Ternovoĭ, V A; Kachko, A V; Ivanova, A V; Ivanisenko, V A; Shvalov, A N; Loktev, V B

    2007-01-01

    Complementary DNA fragments (nucleotides 466-966 and 878-1088) encoding prM protein and polypeptide M31-75-E1-30 of West Nile virus (WNV), strain LEIV-Vlg99-27889-human, were obtained and cloned. Recombinant polypeptides prM and M3175-E1-30 having amino acid sequences corresponding to the cloned cDNA fragments were purified by affinity chromatography. According to ELISA and Western blotting prM protein interacted with polyclonal antibodies against WNV. This is indicative the immunochemical similarity of WNV recombinant and native protein prM. 6 types of species-specific monoclonal antibodies (MAbs) raised against recombinant polypeptide prM recognized at least four epitopes within recombinant polypeptides prM and M31-75-E1-30. MAbs 7D11 were active in the virus - neutralization assay. Analysis of interaction of the MAbs with recombinant polypeptides prM, M31-75-EI-30, E1-180, E260-466 revealed cross-reactive epitopes within 260-466 amino acid residues (aa) of WNV protein E, 31-75 aa of polypeptide M31-75-E1-30 and protein prM. Proposed spatial model of proteins E and M C-end fragments shown similarity of their three-dimensional structures confirming results of immunochemical assay. Neutralization of viral infectivity by MAbs 7D11 raised against epitope within 31-75 aa t of protein M is evidence of important function of C-end region in the process of flaviviral penetration into host cell.

  9. Generation and characterization of a monoclonal antibody against prM protein of West Nile virus.

    Science.gov (United States)

    Guo, Li-Ping; Huo, Hong; Wang, Xiao-Lei; Bu, Zhi-Gao; Hua, Rong-Hong

    2014-12-01

    West Nile virus (WNV), which is an emerging pathogenic flavivirus with increasing distribution worldwide, is the cause of major human and animal health concerns. The pre-membrane (prM) protein of WNV is cleaved during maturation by the furin protease into the structural protein M and a pr-segment. In this study we generated and characterized a monoclonal antibody (MAb) against the WNV prM protein. Western blot analysis showed that the MAb reacted with WNV prM specifically. Immunohistochemistry assays demonstrated that the MAb recognized native prM protein in transfected BHK-21 cells. Preliminary studies were performed to identify the epitope recognized by the MAb using a set of synthesized overlapping peptides spanning the whole length of the prM protein. The MAb reported here may provide a valuable tool for the further exploration of the biological properties and functions of the prM protein and may also be developed for potential clinical applications.

  10. Dengue patients exhibit higher levels of PrM and E antibodies than their asymptomatic counterparts.

    Science.gov (United States)

    Yeo, Adeline Syin Lian; Rathakrishnan, Anusyah; Wang, Seok Mui; Ponnampalavanar, Sasheela; Manikam, Rishya; Sathar, Jameela; Kumari Natkunam, Santha; Sekaran, Shamala Devi

    2015-01-01

    Dengue virus infection is a common tropical disease which often occurs without being detected. These asymptomatic cases provide information in relation to the manifestation of immunological aspects. In this study, we developed an ELISA method to compare neutralizing effects of dengue prM and E antibodies between dengue patients and their asymptomatic household members. Recombinant D2 premembrane (prM) was constructed, cloned, and tested for antigenicity. The recombinant protein was purified and tested with controls by using an indirect ELISA method. Positive dengue serum samples with their asymptomatic pair were then carried out onto the developed ELISA. In addition, commercially available recombinant envelope (E) protein was used to develop an ELISA which was tested with the same set of serum samples in the prM ELISA. Asymptomatic individuals showed preexisting heterotypic neutralizing antibodies. The recombinant prM was antigenically reactive in the developed ELISA. Dengue patients had higher prM and E antibodies compared to their household members. Our study highlights the neutralizing antibodies levels with respect to dengue prM and E between dengue patients and asymptomatic individuals.

  11. CCSDS Spacecraft Monitor and Control Mission Operations Interoperability Prototype

    Science.gov (United States)

    Lucord, Steve; Martinez, Lindolfo

    2009-01-01

    We are entering a new era in space exploration. Reduced operating budgets require innovative solutions to leverage existing systems to implement the capabilities of future missions. Custom solutions to fulfill mission objectives are no longer viable. Can NASA adopt international standards to reduce costs and increase interoperability with other space agencies? Can legacy systems be leveraged in a service oriented architecture (SOA) to further reduce operations costs? The Operations Technology Facility (OTF) at the Johnson Space Center (JSC) is collaborating with Deutsches Zentrum fur Luft- und Raumfahrt (DLR) to answer these very questions. The Mission Operations and Information Management Services Area (MOIMS) Spacecraft Monitor and Control (SM&C) Working Group within the Consultative Committee for Space Data Systems (CCSDS) is developing the Mission Operations standards to address this problem space. The set of proposed standards presents a service oriented architecture to increase the level of interoperability among space agencies. The OTF and DLR are developing independent implementations of the standards as part of an interoperability prototype. This prototype will address three key components: validation of the SM&C Mission Operations protocol, exploration of the Object Management Group (OMG) Data Distribution Service (DDS), and the incorporation of legacy systems in a SOA. The OTF will implement the service providers described in the SM&C Mission Operation standards to create a portal for interaction with a spacecraft simulator. DLR will implement the service consumers to perform the monitor and control of the spacecraft. The specifications insulate the applications from the underlying transport layer. We will gain experience with a DDS transport layer as we delegate responsibility to the middleware and explore transport bridges to connect disparate middleware products. A SOA facilitates the reuse of software components. The prototype will leverage the

  12. Operational climate monitoring from space: the EUMETSAT satellite application facility on climate monitoring (CM-SAF

    Directory of Open Access Journals (Sweden)

    J. Schulz

    2008-05-01

    Full Text Available The Satellite Application Facility on Climate Monitoring (CM-SAF aims at the provision of satellite-derived geophysical parameter data sets suitable for climate monitoring. CM-SAF provides climatologies for Essential Climate Variables (ECV, as required by the Global Climate Observing System implementation plan in support of the UNFCCC. Several cloud parameters, surface albedo, radiation fluxes at the top of the atmosphere and at the surface as well as atmospheric temperature and humidity products form a sound basis for climate monitoring of the atmosphere. The products are categorized in monitoring data sets obtained in near real time and data sets based on carefully intercalibrated radiances. The CM-SAF products are derived from several instruments on-board operational satellites in geostationary and polar orbit, i.e., the Meteosat and NOAA satellites, respectively. The existing data sets will be continued using data from the instruments on-board the new EUMETSAT Meteorological Operational satellite (MetOP. The products have mostly been validated against several ground-based data sets both in situ and remotely sensed. The accomplished accuracy for products derived in near real time is sufficient to monitor variability on diurnal and seasonal scales. Products based on intercalibrated radiance data can also be used for climate variability analysis up to inter-annual scale. A central goal of the recently started Continuous Development and Operations Phase of the CM-SAF (2007–2012 is to further improve all CM-SAF data sets to a quality level that allows for studies of inter-annual variability.

  13. Local randomization in neighbor selection improves PRM roadmap quality

    KAUST Repository

    McMahon, Troy

    2012-10-01

    Probabilistic Roadmap Methods (PRMs) are one of the most used classes of motion planning methods. These sampling-based methods generate robot configurations (nodes) and then connect them to form a graph (roadmap) containing representative feasible pathways. A key step in PRM roadmap construction involves identifying a set of candidate neighbors for each node. Traditionally, these candidates are chosen to be the k-closest nodes based on a given distance metric. In this paper, we propose a new neighbor selection policy called LocalRand(k,K\\'), that first computes the K\\' closest nodes to a specified node and then selects k of those nodes at random. Intuitively, LocalRand attempts to benefit from random sampling while maintaining the higher levels of local planner success inherent to selecting more local neighbors. We provide a methodology for selecting the parameters k and K\\'. We perform an experimental comparison which shows that for both rigid and articulated robots, LocalRand results in roadmaps that are better connected than the traditional k-closest policy or a purely random neighbor selection policy. The cost required to achieve these results is shown to be comparable to k-closest. © 2012 IEEE.

  14. MONITORING DIAGNOSTIC INDICATORS DURING OPERATION OF A PRINT MACHIN

    Directory of Open Access Journals (Sweden)

    Jozef Dobránsky

    2015-11-01

    Full Text Available This article deals with monitoring diagnostic indicators during the operation of a machine used for production of packing materials with a print. It analyses low-frequency vibrations measured in individual spherical roller bearings in eight print positions. The rollers in these positions have a different pressure based on positioning these rollers in relation to the central roller. As a result, the article also deals with a correlation of pressure and level of measured low-frequency vibrations. The speed of the print machine (the speed of a line in meters per minute is a very important variable during its operation, this is why it is important to verify the values of vibrations in various speeds of the line, what can lead to revelation of one or more resonance areas. Moreover, it examines vibrations of the central roller drive and measurement of backlash of transmission cogs of this drive. Based on performed analyses recommendations for an operator of the machine have been conceived.

  15. Structural Health Monitoring under Nonlinear Environmental or Operational Influences

    Directory of Open Access Journals (Sweden)

    Jyrki Kullaa

    2014-01-01

    Full Text Available Vibration-based structural health monitoring is based on detecting changes in the dynamic characteristics of the structure. It is well known that environmental or operational variations can also have an influence on the vibration properties. If these effects are not taken into account, they can result in false indications of damage. If the environmental or operational variations cause nonlinear effects, they can be compensated using a Gaussian mixture model (GMM without the measurement of the underlying variables. The number of Gaussian components can also be estimated. For the local linear components, minimum mean square error (MMSE estimation is applied to eliminate the environmental or operational influences. Damage is detected from the residuals after applying principal component analysis (PCA. Control charts are used for novelty detection. The proposed approach is validated using simulated data and the identified lowest natural frequencies of the Z24 Bridge under temperature variation. Nonlinear models are most effective if the data dimensionality is low. On the other hand, linear models often outperform nonlinear models for high-dimensional data.

  16. Submicron particle monitoring of paving and related road construction operations.

    Science.gov (United States)

    Freund, Alice; Zuckerman, Norman; Baum, Lisa; Milek, Debra

    2012-01-01

    This study identified activities and sources that contribute to ultrafine and other submicron particle exposure that could trigger respiratory symptoms in highway repair workers. Submicron particle monitoring was conducted for paving, milling, and pothole repair operations in a major metropolitan area where several highway repair workers were identified as symptomatic for respiratory illness following exposures at the 2001 World Trade Center disaster site. Exposure assessments were conducted for eight trades involved in road construction using a TSI P-Trak portable condensation particle counter. Direct readings near the workers' breathing zones and observations of activities and potential sources were logged on 7 days on 27 workers using four different models of pavers and two types of millers. Average worker exposure levels ranged from 2 to 3 times background during paving and from 1 to 4 times background during milling. During asphalt paving, average personal exposures to submicron particulates were 25,000-60,000, 28,000-70,000, and 23,000-37,000 particles/ cm(3) for paver operators, screed operators, and rakers, respectively. Average personal exposures during milling were 19,000-111,000, 28,000-81,000, and 19,000 particles/cm(3) for the large miller operators, miller screed operators, and raker, respectively. Personal peak exposures were measured up to 467,000 and 455,000 particles/cm(3) in paving and milling, respectively. Several sources of submicron particles were identified. These included the diesel and electric fired screed heaters; engine exhaust from diesel powered construction vehicles passing by or idling; raking, dumping, and paving of asphalt; exhaust from the hotbox heater; pavement dust or fumes from milling operations, especially when the large miller started and stopped; and secondhand cigarette smoke. To reduce the potential for health effects in workers, over 40 recommendations were made to control exposures, including improved maintenance of

  17. Damage detection and health monitoring of operational structures

    Energy Technology Data Exchange (ETDEWEB)

    James, G.; Mayes, R.; Carne, T.; Reese, G.

    1994-09-01

    Initial damage detection/health monitoring experiments have been performed on three different operational structures: a fracture critical bridge, a composite wind turbine blade, and an aging aircraft. An induced damage test was performed on the Rio Grande/I40 bridge before its demolition. The composite wind turbine test was fatgued to failure with periodic modal testing performed throughout the testing. The front fuselage of a DC-9 aircraft was used as the testbed for an induced damage test. These tests have yielded important insights into techniques for experimental damage detection on real structures. Additionally, the data are currently being used with current damage detection algorithms to further develop the numerical technology. State of the art testing technologies such as, high density modal testing, scanning laser vibrometry and natural excitation testing have also been utilized for these tests.

  18. Operational Performance Analysis of Passive Acoustic Monitoring for Killer Whales

    Energy Technology Data Exchange (ETDEWEB)

    Matzner, Shari; Fu, Tao; Ren, Huiying; Deng, Zhiqun; Sun, Yannan; Carlson, Thomas J.

    2011-09-30

    For the planned tidal turbine site in Puget Sound, WA, the main concern is to protect Southern Resident Killer Whales (SRKW) due to their Endangered Species Act status. A passive acoustic monitoring system is proposed because the whales emit vocalizations that can be detected by a passive system. The algorithm for detection is implemented in two stages. The first stage is an energy detector designed to detect candidate signals. The second stage is a spectral classifier that is designed to reduce false alarms. The evaluation presented here of the detection algorithm incorporates behavioral models of the species of interest, environmental models of noise levels and potential false alarm sources to provide a realistic characterization of expected operational performance.

  19. 40 CFR 63.2164 - If I monitor brew ethanol, what are my monitoring installation, operation, and maintenance...

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 12 2010-07-01 2010-07-01 true If I monitor brew ethanol, what are my... monitor brew ethanol, what are my monitoring installation, operation, and maintenance requirements? (a... considered by us to be generally optimum. Use the brew-to-exhaust correlation equation established under §...

  20. Intra—Operative Facial Nerve Monitoring in Acoustic Neurinoma Surgery

    Institute of Scientific and Technical Information of China (English)

    YANGZhengming; ZHANGZhifeng; 等

    2002-01-01

    Objective To determine the method and significance of facial nerve preservation during acoustic neurinoma surgery by intra-operative facial nerve monitoring(IFNM).Methods 62 patients were randomly assigned to the IFNM or the control group.Facial nerve function(FNF)was assessed by a modified House-Brackmann grading(HB)before the operation,10 days and every two months after surgery and com,pared between the two groups. Results Ten days after surgery,26/32 patients in the IFNM group and 15/30 patients in the control group had FNF HB grade,Ⅰ-Ⅲ;FNF HB gradeⅣ-Ⅴ was prestent in 6/32 in the IFNM group and 15/30 in the control group.During follow-up,29/32 patients in the IFNM group and 20/20 patients in the control group had FNF HB gradeⅠ-Ⅲ;FNF HB gradeⅣ-Ⅴ was present in 3/32 in the IFNM group and 10/30 in the control group.All differnces were statistcally significant.Conclusion IFNM significantly improved anatomic and functional facial nerve preservation as well as the quality of life.

  1. 78 FR 73112 - Monitoring System Conditions-Transmission Operations Reliability Standards; Interconnection...

    Science.gov (United States)

    2013-12-05

    ..., performance, and maintenance of real-time monitoring and analysis capabilities for reliability coordinators... Reliability Standards; Interconnection Reliability Operations and Coordination Reliability Standards AGENCY... Transmission Operations and Interconnection Reliability Operations and Coordination Reliability Standards...

  2. Enhancement of partial robust M-regression (PRM) performance using Bisquare weight function

    Science.gov (United States)

    Mohamad, Mazni; Ramli, Norazan Mohamed; Ghani@Mamat, Nor Azura Md; Ahmad, Sanizah

    2014-09-01

    Partial Least Squares (PLS) regression is a popular regression technique for handling multicollinearity in low and high dimensional data which fits a linear relationship between sets of explanatory and response variables. Several robust PLS methods are proposed to accommodate the classical PLS algorithms which are easily affected with the presence of outliers. The recent one was called partial robust M-regression (PRM). Unfortunately, the use of monotonous weighting function in the PRM algorithm fails to assign appropriate and proper weights to large outliers according to their severity. Thus, in this paper, a modified partial robust M-regression is introduced to enhance the performance of the original PRM. A re-descending weight function, known as Bisquare weight function is recommended to replace the fair function in the PRM. A simulation study is done to assess the performance of the modified PRM and its efficiency is also tested in both contaminated and uncontaminated simulated data under various percentages of outliers, sample sizes and number of predictors.

  3. Physical and rehabilitation medicine (PRM) care pathways: "patients after knee ligament surgery".

    Science.gov (United States)

    Calmels, P; Ribinik, P; Barrois, B; Le Moine, F; Yelnik, A-P

    2011-11-01

    This document is part of a series of documents designed by the French Physical and Rehabilitation Medicine Society (Sofmer) and the French Federation of PRM (Fedmer). These documents describe the needs for or a specific type of patients; PRM care objectives, human and material resources to be implemented, chronology as well as expected outcomes. "Care pathways in PRM" is a short document designed to enable the reader (physicians, decision-maker, administrator, lawyer or finance manager) to quickly apprehend the needs of these patients and the available therapeutic care structures for proper organization and pricing of these activities. Patients after knee ligament surgery are classified into four care sequences and two clinical categories, taking into account personal and environmental factors that could influence patients' needs, in accordance with the International Classification of Functioning (WHO).

  4. Physical and rehabilitation medicine (PRM) care pathways: "patients after total knee arthroplasty".

    Science.gov (United States)

    Ribinik, P; Le Moine, F; de Korvin, G; Coudeyre, E; Genty, M; Rannou, F; Yelnik, A; Calmels, P

    2012-11-01

    This document is part of a series of documents designed by the French Physical and Rehabilitation Medicine Society (SOFMER) and the French Federation of PRM (FEDMER). These documents describe the needs for or a specific type of patients; PRM care objectives, human and material resources to be implemented, chronology as well as expected outcomes. "Care pathways in PRM" is a short document designed to enable the reader (physicians, decision-maker, administrator, lawyer or finance manager) to quickly apprehend the needs of these patients and the available therapeutic care structures for proper organization and pricing of these activities. Patients after total knee arthroplasty are classified into three care sequences and two clinical categories, each one being treated with the same six parameters according to the International Classification of Functioning, Disability and Health (WHO), while taking into account personal and environmental factors that could influence the needs of these patients.

  5. Physical and rehabilitation medicine (PRM) care pathways: "patients after rotator cuff tear surgery".

    Science.gov (United States)

    Ribinik, P; Calmels, P; Barrois, B; Le Moine, F; Yelnik, A P

    2011-11-01

    This document is part of a series of documents designed by the French Physical and Rehabilitation Medicine Society (Sofmer) and the French Federation of PRM (Fedmer). These documents describe the needs for or a specific type of patients; PRM care objectives, human and material resources to be implemented, chronology as well as expected outcomes. "Care pathways in PRM" is a short document designed to enable the reader (physicians, decision-maker, administrator, lawyer or finance manager) to quickly apprehend the needs of these patients and the available therapeutic care structures for proper organization and pricing of these activities. Patients after rotator cuff tear surgery are classified into four care sequences and two clinical categories, taking into account personal and environmental factors that could influence patients' needs, in accordance with the International Classification of Functioning (ICF) (WHO).

  6. Physical and rehabilitation medicine (PRM) care pathways: "patients after total hip arthroplasty".

    Science.gov (United States)

    Ribinik, P; Le Moine, F; de Korvin, G; Coudeyre, E; Genty, M; Rannou, F; Yelnik, A; Calmels, P

    2012-11-01

    This document is part of a series of documents designed by the French Physical and Rehabilitation Medicine Society (SOFMER) and the French Federation of PRM (FEDMER). These documents describe the needs for or a specific type of patients; PRM care objectives, human and material resources to be implemented, chronology as well as expected outcomes. "Care pathways in PRM" is a short document designed to enable the reader (physicians, decision-maker, administrator, lawyer or finance manager) to quickly apprehend the needs of these patients and the available therapeutic care structures for proper organization and pricing of these activities. Patients after total hip arthroplasty are classified into three care sequences and two clinical categories, each one being treated with the same six parameters according to the International Classification of Functioning, Disability and Health (WHO), while taking into account personal and environmental factors that could influence the needs of these patients.

  7. Mediterranean monitoring and forecasting operational system for Copernicus Marine Service

    Science.gov (United States)

    Coppini, Giovanni; Drudi, Massimiliano; Korres, Gerasimos; Fratianni, Claudia; Salon, Stefano; Cossarini, Gianpiero; Clementi, Emanuela; Zacharioudaki, Anna; Grandi, Alessandro; Delrosso, Damiano; Pistoia, Jenny; Solidoro, Cosimo; Pinardi, Nadia; Lecci, Rita; Agostini, Paola; Cretì, Sergio; Turrisi, Giuseppe; Palermo, Francesco; Konstantinidou, Anna; Storto, Andrea; Simoncelli, Simona; Di Pietro, Pier Luigi; Masina, Simona; Ciliberti, Stefania Angela; Ravdas, Michalis; Mancini, Marco; Aloisio, Giovanni; Fiore, Sandro; Buonocore, Mauro

    2016-04-01

    The MEDiterranean Monitoring and Forecasting Center (Med-MFC) is part of the Copernicus Marine Environment Monitoring Service (CMEMS, http://marine.copernicus.eu/), provided on an operational mode by Mercator Ocean in agreement with the European Commission. Specifically, Med MFC system provides regular and systematic information about the physical state of the ocean and marine ecosystems for the Mediterranean Sea. The Med-MFC service started in May 2015 from the pre-operational system developed during the MyOcean projects, consolidating the understanding of regional Mediterranean Sea dynamics, from currents to biogeochemistry to waves, interfacing with local data collection networks and guaranteeing an efficient link with other Centers in Copernicus network. The Med-MFC products include analyses, 10 days forecasts and reanalysis, describing currents, temperature, salinity, sea level and pelagic biogeochemistry. Waves products will be available in MED-MFC version in 2017. The consortium, composed of INGV (Italy), HCMR (Greece) and OGS (Italy) and coordinated by the Euro-Mediterranean Centre on Climate Change (CMCC, Italy), performs advanced R&D activities and manages the service delivery. The Med-MFC infrastructure consists of 3 Production Units (PU), for Physics, Biogechemistry and Waves, a unique Dissemination Unit (DU) and Archiving Unit (AU) and Backup Units (BU) for all principal components, guaranteeing a resilient configuration of the service and providing and efficient and robust solution for the maintenance of the service and delivery. The Med-MFC includes also an evolution plan, both in terms of research and operational activities, oriented to increase the spatial resolution of products, to start wave products dissemination, to increase temporal extent of the reanalysis products and improving ocean physical modeling for delivering new products. The scientific activities carried out in 2015 concerned some improvements in the physical, biogeochemical and

  8. 杜比PRM-4200荣获艾美奖

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    美国电视艺术与科学学院将黄金时段艾美奖工程开发杰出成就奖,授予杜比PRM-4200专业视频效果测试校正仪。PRM-4200获奖标志着美国国家电视艺术与科学学院(NATAS)和美国电视艺术与科学学院(ATAS)第12次授予杜比产品技术奖项。

  9. Operating Room Traffic: Is There Any Role of Monitoring It?

    Science.gov (United States)

    Parikh, Shital N.; Grice, Salih S.; Schnell, Beverly M.; Salisbury, Shelia R.

    2010-01-01

    Background Operating room (OR) human traffic has been implicated as a cause of surgical site infection. We first observed the normal human traffic pattern in our Pediatric Orthopaedic ORs, then examined the effect of surveillance on that traffic pattern. Methods This study consisted of two phases: phase I sought to observe the OR traffic pattern (number of door swings, maximum and minimum number of OR personnel, number of OR personnel at 30 minute intervals, or changes in nursing, anesthesia or surgeon staff) during surgical cases without OR personnel being notified, and for phase II, the same traffic pattern was monitored with their knowledge. Results 2442 minutes of surgical time were observed in phase I, and 1908 minutes were observed in phase II. There was no difference (p=0.06) in the time between door swings between phase I (1.39 minutes) and phase II (1.70), no difference (p=1.000) in the maximum number of people in the OR between phase I (11.5 people, range: 7–15 people) and phase II (11.5 people, range: 8–20 people), no difference (p=1.000) in the minimum number of people in the OR between phase I (4.67 people, range: 4–6 people) and phase II (4.71 people, range: 3–6 people). There was a difference in the time between door swings (p=0.03) and maximum number of people in the OR (p=0.005) based on length of surgery (less or more than120 minutes). There was no difference in the time between door swings (p=0.11), but there was a difference in the maximum number of people in the OR (p=0.002) based on type of surgery (spine vs. others). Conclusion There was no role of surveillance of human traffic in the OR. To achieve any change in the OR traffic pattern, monitoring alone may not be sufficient; other novel techniques or incentives may need to be considered. PMID:20733430

  10. The Application of Plant Resource Manager PRM in Oil Refineries%工厂资源管理系统(PRM)在炼油企业的应用

    Institute of Scientific and Technical Information of China (English)

    乔祯; 姚强; 王冰; 田霖

    2010-01-01

    PRM(Plant Resource Manager)是用以提高现场设备管理及维护效率的现场设备管理软件包.通过分析该软件包及其应用的实际效果,阐述了这种管理软件在过程生产与设备管理中所起的巨大作用.

  11. Possibilities of making use of integrated emission monitoring system for inspection of electroprecipitators operation

    Energy Technology Data Exchange (ETDEWEB)

    Knitter, J.; Matys, T. [Gdansk Thermal-Electric Power Station Complex S.A., Gdansk (Poland)

    1997-12-31

    Microprocessor and computer control devices for ESP operation and integrated emission monitoring systems are discussed. An operating ESP inspection system for the Gdansk power station complex is determined. 8 refs., 1 fig.

  12. Local clinical quality monitoring for detection of excess operative deaths.

    Science.gov (United States)

    Arrowsmith, J E; Powell, S J; Nashef, S A M

    2006-05-01

    A monitoring system for cardiac surgery has been in use at Papworth Hospital for 10 years. We wished to determine whether this system would have detected an increase in deaths associated with a single practitioner, whether a poorly performing doctor or a serial killer such as Dr Harold Shipman, whose activities went undetected in the absence of a monitoring system for nearly a quarter of a century. Random extra deaths were artificially introduced into the practice of a surgeon and an anaesthetist in a way that broadly reproduced Shipman's pattern. The standard monitoring system was then used to analyse the hypothetical data thus generated. Using the current standard monitoring, the excess deaths would have been detected in less than 10 months. Suspicions would have been raised even earlier. Robust local quality monitoring of risk-adjusted outcomes is possible and, in our opinion, essential.

  13. Mutation in West Nile Virus Structural Protein prM during Human Infection.

    Science.gov (United States)

    Lustig, Yaniv; Lanciotti, Robert S; Hindiyeh, Musa; Keller, Nathan; Milo, Ron; Mayan, Shlomo; Mendelson, Ella

    2016-09-01

    A mutation leading to substitution of a key amino acid in the prM protein of West Nile virus (WNV) occurred during persistent infection of an immunocompetent patient. WNV RNA persisted in the patient's urine and serum in the presence of low-level neutralizing antibodies. This case demonstrates active replication of WNV during persistent infection.

  14. Mutations in the West Nile prM protein affect VLP and virion secretion in vitro.

    Science.gov (United States)

    Calvert, Amanda E; Huang, Claire Y-H; Blair, Carol D; Roehrig, John T

    2012-11-10

    Mutation of the West Nile virus-like particle (WN VLP) prM protein (T20D, K31A, K31V, or K31T) results in undetectable VLP secretion from transformed COS-1 cells. K31 mutants formed intracellular prM-E heterodimers; however these proteins remained in the ER and ER-Golgi intermediary compartments of transfected cells. The T20D mutation affected glycosylation, heterodimer formation, and WN VLP secretion. When infectious viruses bearing the same mutations were used to infect COS-1 cells, K31 mutant viruses exhibited delayed growth and reduced infectivity compared to WT virus. Epitope maps of WN VLP and WNV prM were also different. These results suggest that while mutations in the prM protein can reduce or eliminate secretion of WN VLPs, they have less effect on virus. This difference may be due to the quantity of prM in WN VLPs compared to WNV or to differences in maturation, structure, and symmetry of these particles.

  15. 40 CFR 63.2163 - If I monitor fermenter exhaust, what are my monitoring installation, operation, and maintenance...

    Science.gov (United States)

    2010-07-01

    ... Hazardous Air Pollutants: Manufacturing of Nutritional Yeast Testing and Initial Compliance Requirements... are my monitoring installation, operation, and maintenance requirements? 63.2163 Section 63.2163... maintenance requirements? (a) Each CEMS must be installed, operated, and maintained according to the...

  16. Microvibration monitoring: some recent experiences in an operating microelectronics facility

    Science.gov (United States)

    Hassett, Kevin

    1992-02-01

    Major construction work is currently underway at Intel''s Aloha, Oregon, campus. Because of concerns about the effects that construction-generated vibration might have on adjacent ongoing microelectronics manufacturing activities, two important steps were taken. The first of these was to establish guidelines that would be followed by the construction contractor to limit vibration disturbance. The second was to install a computer-based monitoring system that would continuously measure the vibration on the floor of the microelectronics manufacturing facility. In this way, the vibration effects of the construction activities would be monitored and adjusted, by modifying procedures, if necessary. The monitoring program is discussed in this paper. The major characteristics of the monitoring system, the placement of the transducers, and the ways in which the data were managed are described. Some typical data are shown and discussed.

  17. Single point mutation in tick-borne encephalitis virus prM protein induces a reduction of virus particle secretion.

    Science.gov (United States)

    Yoshii, Kentarou; Konno, Akihiro; Goto, Akiko; Nio, Junko; Obara, Mayumi; Ueki, Tomotaka; Hayasaka, Daisuke; Mizutani, Tetsuya; Kariwa, Hiroaki; Takashima, Ikuo

    2004-10-01

    Flaviviruses are assembled to bud into the lumen of the endoplasmic reticulum (ER) and are secreted through the vesicle transport pathway. Virus envelope proteins play important roles in this process. In this study, the effect of mutations in the envelope proteins of tick-borne encephalitis (TBE) virus on secretion of virus-like particles (VLPs), using a recombinant plasmid expression system was analysed. It was found that a single point mutation at position 63 in prM induces a reduction in secretion of VLPs. The mutation in prM did not affect the folding of the envelope proteins, and chaperone-like activity of prM was maintained. As observed by immunofluorescence microscopy, viral envelope proteins with the mutation in prM were scarce in the Golgi complex, and accumulated in the ER. Electron microscopic analysis of cells expressing the mutated prM revealed that many tubular structures were present in the lumen. The insertion of the prM mutation at aa 63 into the viral genome reduced the production of infectious virus particles. This data suggest that prM plays a crucial role in the virus budding process.

  18. First Operation of the Abort Gap Monitors for LHC

    CERN Document Server

    Bart Pedersen, S; Bravin, E; Boccardi, A; Goldblatt, A; Jeff, A; Roncarolo, F; Fisher, A

    2010-01-01

    The Large Hadron Collider (LHC) beam-dump system relies on extraction kickers that need 3 microseconds to rise to their nominal field. Since particles transiting the kickers during the rise will not be dumped properly, the proton population in this interval must always remain below quench and damage limits. A specific monitor to measure the particle population of this gap has been designed based on the detection of synchrotron radiation using a gated photomultiplier. Since the quench and damage limits change with the beam energy, the acceptable population in the abort gap and the settings of the monitor must adapt accordingly. This paper presents the design of the monitor, the calibration procedure and the detector performance with beam.

  19. 40 CFR 60.734 - Monitoring of emissions and operations.

    Science.gov (United States)

    2010-07-01

    ... operator of an affected facility subject to the provisions of this subpart who uses a dry control device to... clay vibrating grate dryer, a bentonite rotary dryer, a diatomite flash dryer, a diatomite rotary... section. (d) The owner or operator of an affected facility subject to the provisions of this subpart...

  20. 40 CFR 60.153 - Monitoring of operations.

    Science.gov (United States)

    2010-07-01

    ...) The owner or operator of any multiple hearth, fluidized bed, or electric sludge incinerator subject to...) Install, calibrate, maintain and operate temperature measuring devices at every hearth in multiple hearth... zones of electric incinerators. For multiple hearth furnaces, a minimum of one temperature...

  1. Operation and monitoring guidelines and the development of a ...

    African Journals Online (AJOL)

    2009-03-31

    Mar 31, 2009 ... 35 No. 4 July 2009. ISSN 1816-7950 = Water SA (on-line). 379 ... Keywords: irrigation, coal mine water, monitoring guidelines. Introduction .... production of several crops irrigated with gypsiferous mine water was tested in a ...

  2. Integrating Social Media Monitoring Into Public Health Emergency Response Operations.

    Science.gov (United States)

    Hadi, Tamer A; Fleshler, Keren

    2016-10-01

    Social media monitoring for public health emergency response and recovery is an essential response capability for any health department. The value of social media for emergency response lies not only in the capacity to rapidly communicate official and critical incident information, but as a rich source of incoming data that can be gathered to inform leadership decision-making. Social media monitoring is a function that can be formally integrated into the Incident Command System of any response agency. The approach to planning and required resources, such as staffing, logistics, and technology, is flexible and adaptable based on the needs of the agency and size and scope of the emergency. The New York City Department of Health and Mental Hygiene has successfully used its Social Media Monitoring Team during public health emergency responses and planned events including major Ebola and Legionnaires' disease responses. The concepts and implementations described can be applied by any agency, large or small, interested in building a social media monitoring capacity. (Disaster Med Public Health Preparedness. 2016;page 1 of 6).

  3. Silicon solar cell monitors high temperature furnace operation

    Science.gov (United States)

    Zellner, G. J.

    1968-01-01

    Silicon solar cell, attached to each viewpoint, monitors that incandescent emission from the hot interior of a furnace without interfering with the test assembly or optical pyrometry during the test. This technique can provide continuous indication of hot spots or provide warning of excessive temperatures in cooler regions.

  4. Real Time Distributed Embedded Oscillator Operating Frequency Monitoring

    Science.gov (United States)

    Pollock, Julie (Inventor); Oliver, Brett D. (Inventor); Brickner, Christopher (Inventor)

    2013-01-01

    A method for clock monitoring in a network is provided. The method comprises receiving a first network clock signal at a network device and comparing the first network clock signal to a local clock signal from a primary oscillator coupled to the network device.

  5. Monitoring of flash visual evoked potentials during neurosurgical operations.

    Science.gov (United States)

    Cedzich, C; Schramm, J

    1990-01-01

    In summary, our results suggest that flash VEP monitoring is not specific for visual acuity and has not proved helpful as an intraoperative warning system. The future challenge will be to devise a method which activates only those fibers specific to visual acuity and which provides reproducible and reliable information quickly enough that adjustments in patient management can be made.

  6. Monocyte development inhibitor PRM-151 decreases corneal myofibroblast generation in rabbits.

    Science.gov (United States)

    Santhiago, M R; Singh, V; Barbosa, F L; Agrawal, V; Wilson, S E

    2011-11-01

    This study investigated whether PRM-151 (Promedior, Inc., Malvern, PA), a recombinant form of human pentraxin-2 (PTX-2, also referred to as serum amyloid P, hSAP), that inhibits differentiation of circulating monocytes into fibrocytes and profibrotic macrophages, could modulate generation of myofibroblasts after opacity-producing corneal injury in rabbits, and, therefore, have potential to reduce or prevent haze after PRK. Nine diopter PRK for myopia was performed with the VISX S4 IR laser. Four groups of 6 animals were treated in masked fashion: Group 1: 30 μl of topical PRM-151 (20 mg/ml) 6 times a day for 5 days; Group 2: 30 μl topical vehicle 6 times a day for 5 days; Group 3: 200 μl sub-conjunctival PRM-151 (total injection of 4 mg) immediately after surgery and every other day until day 8; Group 4: 200 μl sub-conjunctival injections of vehicle according to the same schedule as group 3. At one month after PRK, the animals were euthanized and immunohistochemistry was performed for the myofibroblast marker α-smooth muscle actin (SMA). The density of SMA+ cells/400× field in the central stroma was determined in each cornea. Myofibroblast density at one month after surgery was significantly lower (p = 0.006) after sub-conjunctival PRM-151 treatment (5.8 ± 2.8 cells/400× stromal field) compared to sub-conjunctival vehicle treatment (15.3 ± 2.9 cells/400× stromal field). There was no significant (p = 0.27) decrease in stromal myofibroblasts triggered by topical PRM-151 treatment (11.8 ± 6.6 cells/400× stromal field) compared to the topical vehicle treatment (14.2.8 ± 6.2 cells/400× stromal field). PRM-151 inhibits myofibroblast generation when administered by sub-conjunctival injection, but not when administered topically, after opacity-producing corneal injury. This study provides additional confirmation that bone marrow-derived cells contribute to corneal myofibroblast generation.

  7. Standard Operating Procedures, MCSP Monarch and Plant Monitoring, 2016

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This record contains the six Standard Operating Procedure (SOP) of the initial survey instructions (ISI) developed and followed for surveys conducted as part of the...

  8. Structural Health Monitoring in Changing Operational Conditions Using Tranmissibility Measurements

    Directory of Open Access Journals (Sweden)

    Christof Devriendt

    2010-01-01

    Full Text Available This article uses frequency domain transmissibility functions for detecting and locating damage in operational conditions. In recent articles numerical and experimental examples were presented and the possibility to use the transmissibility concept for damage detection seemed quite promising. In the work discussed so far, it was assumed that the operational conditions were constant, the structure was excited by a single input in a fixed location. Transmissibility functions, defined as a simple ratio between two measured responses, do depend on the amplitudes or locations of the operational forces. The current techniques fail in the case of changing operational conditions. A suitable operational damage detection method should however be able to detect damage in a very early stage even in the case of changing operational conditions. It will be demonstrated in this paper that, by using only a small frequency band around the resonance frequencies of the structure, the existing methods can still be used in a more robust way. The idea is based on the specific property that the transmissibility functions become independent of the loading condition in the system poles. A numerical and experimental validation will be given.

  9. Groundwater Monitoring at the 1100-EM-1 Operable Unit

    Energy Technology Data Exchange (ETDEWEB)

    Newcomer, Darrell R.

    2007-04-25

    The purpose of this report is to provide a comprehensive summary of the distribution and trends of volatile organic compound concentrations near USDOE’s Horn Rapids Landfill (HRL). This report focuses mainly on the TCE plume monitored in the top of the unconfined aquifer near the HRL, but also addresses potential breakdown products of TCE. TCE concentrations in deep portions of the unconfined aquifer and the underlying confined aquifer are discussed to show the vertical extent of contamination. This report incorporates TCE data from offsite wells at the AREVA facility south of the Hanford Site. Discussion of TCE in groundwater in the 300 Area is included to differentiate between contaminant plumes and their sources in the 300 Area and near the HRL. Chromium monitoring results from a specific well downgradient of the 1171 Building is also included.

  10. Electronic Performance Support for Operational Systems: A Case Study of the Link Monitor and Control Operator Assistant

    Science.gov (United States)

    Hill, Randall W., Jr.; Cooper, Lynne P.

    1993-01-01

    For complex operational systems, help needs to come from the inside out. It is often not realistic to call a help desk for problems that need immediate attention, especially for tasks that put a heavy cognitive load on the system operator. This session addresses the issues associated with providing electronic performance support for operational systems, including situations where the system is already fielded and can only change through evolution rather than revolution. We present a case study based on our experiences in developing the Link Monitor and Control Operator Assistant for NASA's Deep Space Network (DSN). The goals of the Operator Assistant are to improve the operability of the system and increase the efficiency of mission operations.

  11. Relative contribution of dengue prM- and E-specific polyclonal antibodies to neutralization and enhancement.

    Science.gov (United States)

    Rodpothong, P; Boonarkart, Ch; Ruangrung, K; Onsirisakul, N; Kanistanon, D; Auewarakul, P

    Viral surface proteins, premembrane protein (prM) and envelope (E) protein have been shown to induce a production of antibodies that are involved in both enhancement and neutralization. To explore the feasibility of modifying the relative immune responses to prM and E proteins, four DNA constructs were created and administered into groups of Balb/c mice; pPW01 contains prM and E genes of DENV1, pPW02 contains prM and E genes of DENV2, pPW03 contains DENV1 prM and DENV2 E, and pPW04 contains DENV2 prM and DENV1 E. Exchange of either prM or E from a heterologous serotype does not appear to have an effect on the immunogenicity of the proteins. We have proved that the chimeric pPW03 and pPW04 constructs can produce humoral response in mice. Immunized sera were subjected to neutralization and enhancement assays against DENV2. The results showed that only serotype-specific anti-E antibodies conferred protective function, while the cross-reactive anti-E and anti-prM enhanced infection. In addition, the enhancement of DENV2 infection exhibited a serotype-preference for anti-E antibodies while such response was not observed with anti-prM, reflecting a degree of structural conservation of prM. Taken together, neutralization and enhancement appeared to occur at the same time during the course of infection. Successful prevention of severe symptoms of DENV infection depends on the ability to induce high levels of neutralizing antibodies to subdue the effect of enhancing antibodies.

  12. PRM-151 (recombinant human serum amyloid P/pentraxin 2) for the treatment of fibrosis.

    Science.gov (United States)

    Duffield, Jeremy S; Lupher, Mark L

    2010-06-01

    Serum amyloid P or pentraxin 2 (PTX2) is a highly phylogenetically conserved, naturally circulating plasma protein and a soluble pattern recognition receptor of the innate immune system. The unique binding activities of PTX2 suggest that it may localize specifically to sites of injury and function to aid in the removal of damaged tissue. The recent discovery of its ability to regulate certain monocyte differentiation states has identified PTX2 as a novel and potentially powerful antifibrotic agent. A fully recombinant form of the human PTX2 protein, designated PRM-151, has recently initiated human clinical trials. Here we review the molecular, cellular and structural biology of PRM-151/PTX2 in vitro and in several in vivo preclinical models of fibrotic disease that demonstrate its potential as a first-in-class natural modulator of fibrotic pathology with significant potential to treat a wide variety of human diseases.

  13. Optical monitoring and operational modal analysis of large wind turbines

    NARCIS (Netherlands)

    Özbek, M.

    2013-01-01

    Identification of the dynamic properties and the corresponding structural response of wind turbines is essential for optimizing the energy produced, ensuring safe and reliable operation and increasing the life-time of the system. As the sizes of modern wind turbines increase, their dynamic behaviors

  14. 40 CFR 60.115a - Monitoring of operations.

    Science.gov (United States)

    2010-07-01

    ... the sample(s). (c) The true vapor pressure of each type of crude oil with a Reid vapor pressure less...) The owner or operator of each storage vessel equipped with a vapor recovery and return or disposal... petroleum liquid stored, the period of storage, and the maximum true vapor pressure of that liquid...

  15. 40 CFR 60.113 - Monitoring of operations.

    Science.gov (United States)

    2010-07-01

    ... the sample(s). (c) The true vapor pressure of each type of crude oil with a Reid vapor pressure less...). (2) Each owner or operator of each affected facility equipped with a vapor recovery and return or... petroleum liquid stored, the period of storage, and the maximum true vapor pressure of that liquid...

  16. Optical monitoring and operational modal analysis of large wind turbines

    NARCIS (Netherlands)

    Özbek, M.

    2013-01-01

    Identification of the dynamic properties and the corresponding structural response of wind turbines is essential for optimizing the energy produced, ensuring safe and reliable operation and increasing the life-time of the system. As the sizes of modern wind turbines increase, their dynamic behaviors

  17. Digital image monitoring to optimise safe port operation

    CSIR Research Space (South Africa)

    Phelp, D

    2008-11-01

    Full Text Available This paper describes a low cost video system ‘Harbour Watch’, which can be used to support safe port operations, especially in developing countries. Preset digital images are geo-referenced and then archived for later analysis to improve...

  18. 40 CFR 60.403 - Monitoring of emissions and operations.

    Science.gov (United States)

    2010-07-01

    ... of the gases discharged into the atmosphere from any phosphate rock dryer, calciner, or grinder. The... operate a device for measuring the phosphate rock feed to any affected dryer, calciner, or grinder. The... phosphate rock dryer, calciner, or grinder subject to paragraph (a) of this section exceeds the...

  19. Prm3p is a pheromone-induced peripheral nuclear envelope protein required for yeast nuclear fusion.

    Science.gov (United States)

    Shen, Shu; Tobery, Cynthia E; Rose, Mark D

    2009-05-01

    Nuclear membrane fusion is the last step in the mating pathway of the yeast Saccharomyces cerevisiae. We adapted a bioinformatics approach to identify putative pheromone-induced membrane proteins potentially required for nuclear membrane fusion. One protein, Prm3p, was found to be required for nuclear membrane fusion; disruption of PRM3 caused a strong bilateral defect, in which nuclear congression was completed but fusion did not occur. Prm3p was localized to the nuclear envelope in pheromone-responding cells, with significant colocalization with the spindle pole body in zygotes. A previous report, using a truncated protein, claimed that Prm3p is localized to the inner nuclear envelope. Based on biochemistry, immunoelectron microscopy and live cell microscopy, we find that functional Prm3p is a peripheral membrane protein exposed on the cytoplasmic face of the outer nuclear envelope. In support of this, mutations in a putative nuclear localization sequence had no effect on full-length protein function or localization. In contrast, point mutations and deletions in the highly conserved hydrophobic carboxy-terminal domain disrupted both protein function and localization. Genetic analysis, colocalization, and biochemical experiments indicate that Prm3p interacts directly with Kar5p, suggesting that nuclear membrane fusion is mediated by a protein complex.

  20. Transposon Insertion Reveals pRM, a Plasmid of Rickettsia monacensis▿

    OpenAIRE

    Baldridge, Gerald D.; Burkhardt, Nicole Y.; Felsheim, Roderick F.; Timothy J Kurtti; Munderloh, Ulrike G.

    2007-01-01

    Until the recent discovery of pRF in Rickettsia felis, the obligate intracellular bacteria of the genus Rickettsia (Rickettsiales: Rickettsiaceae) were thought not to possess plasmids. We describe pRM, a plasmid from Rickettsia monacensis, which was detected by pulsed-field gel electrophoresis and Southern blot analyses of DNA from two independent R. monacensis populations transformed by transposon-mediated insertion of coupled green fluorescent protein and chloramphenicol acetyltransferase m...

  1. Groundwater Monitoring Plan for the Reactor Technology Complex Operable Unit 2-13

    Energy Technology Data Exchange (ETDEWEB)

    Richard P. Wells

    2007-03-23

    This Groundwater Monitoring Plan describes the objectives, activities, and assessments that will be performed to support the on-going groundwater monitoring requirements at the Reactor Technology Complex, formerly the Test Reactor Area (TRA). The requirements for groundwater monitoring were stipulated in the Final Record of Decision for Test Reactor Area, Operable Unit 2-13, signed in December 1997. The monitoring requirements were modified by the First Five-Year Review Report for the Test Reactor Area, Operable Unit 2-13, at the Idaho National Engineering and Environmental Laboratory to focus on those contaminants of concern that warrant continued surveillance, including chromium, tritium, strontium-90, and cobalt-60. Based upon recommendations provided in the Annual Groundwater Monitoring Status Report for 2006, the groundwater monitoring frequency was reduced to annually from twice a year.

  2. Physical and rehabilitation medicine (PRM) care pathways: adults with severe traumatic brain injury.

    Science.gov (United States)

    Pradat-Diehl, P; Joseph, P-A; Beuret-Blanquart, F; Luauté, J; Tasseau, F; Remy-Neris, O; Azouvi, P; Sengler, J; Bayen, É; Yelnik, A; Mazaux, J-M

    2012-11-01

    This document is part of a series of guidelines documents designed by the French Physical and Rehabilitation Medicine Society (SOFMER) and the French Federation of PRM (FEDMER). These reference documents focus on a particular pathology (here patients with severe TBI). They describe for each given pathology patients' clinical and social needs, PRM care objectives and necessary human and material resources of the pathology-dedicated pathway. 'Care pathways in PRM' is therefore a short document designed to enable readers (physician, decision-maker, administrator, lawyer, finance manager) to have a global understanding of available therapeutic care structures, organization and economic needs for patients' optimal care and follow-up. After a severe traumatic brain injury, patients might be divided into three categories according to impairment's severity, to early outcomes in the intensive care unit and to functional prognosis. Each category is considered in line with six identical parameters used in the International Classification of Functioning, Disability and Health (World Health Organization), focusing thereafter on personal and environmental factors liable to affect the patients' needs.

  3. Monoclonal antibody against Saint Louis encephalitis prM viral protein.

    Science.gov (United States)

    Pupo-Antúnez, M; Vázquez, S; Sosa, A L; Caballero, Y; Vásquez, Y; Morier, L; Álvarez, M; Guzmán, M G

    2015-06-15

    Saint Louis encephalitis virus belongs to Flavivirus genus; Flaviviridae family jointly with other medically important flaviviruses including dengue virus and West Nile virus. The biological properties and functions of prM flavivirus protein are under investigation due to its importance in the generation of infectious virion and host interactions. Monoclonal antibodies have become powerful tools in this approach. Also the use of monoclonal antibodies has been successfully applied for antigenic analysis, clinical diagnosis and treatments. Here, using an immunofluorescence assay we describe a monoclonal antibody (mAb 3D2) that uniquely recognizes native prM Saint Louis encephalitis virus protein expressed in either C6/36-HT or Vero cells. In conclusion, mAb3D2 has significant potential for use in (a) the diagnosis of infections caused by this virus and (b) therapeutic use to treat patients infected by this virus and fundamental research to understand the role of the prM in the Saint Louis encephalitis virus infectious process.

  4. Learning neuroendoscopy with an exoscope system (video telescopic operating monitor): Early clinical results

    Science.gov (United States)

    Parihar, Vijay; Yadav, Y. R.; Kher, Yatin; Ratre, Shailendra; Sethi, Ashish; Sharma, Dhananjaya

    2016-01-01

    Context: Steep learning curve is found initially in pure endoscopic procedures. Video telescopic operating monitor (VITOM) is an advance in rigid-lens telescope systems provides an alternative method for learning basics of neuroendoscopy with the help of the familiar principle of microneurosurgery. Aims: The aim was to evaluate the clinical utility of VITOM as a learning tool for neuroendoscopy. Materials and Methods: Video telescopic operating monitor was used 39 cranial and spinal procedures and its utility as a tool for minimally invasive neurosurgery and neuroendoscopy for initial learning curve was studied. Results: Video telescopic operating monitor was used in 25 cranial and 14 spinal procedures. Image quality is comparable to endoscope and microscope. Surgeons comfort improved with VITOM. Frequent repositioning of scope holder and lack of stereopsis is initial limiting factor was compensated for with repeated procedures. Conclusions: Video telescopic operating monitor is found useful to reduce initial learning curve of neuroendoscopy.

  5. C-terminal helical domains of dengue virus type 4 E protein affect the expression/stability of prM protein and conformation of prM and E proteins.

    Directory of Open Access Journals (Sweden)

    Wen-Yang Tsai

    Full Text Available BACKGROUND: The envelope (E protein of dengue virus (DENV is the major immunogen for dengue vaccine development. At the C-terminus are two α-helices (EH1 and EH2 and two transmembrane domains (ET1 and ET2. After synthesis, E protein forms a heterodimer with the precursor membrane (prM protein, which has been shown as a chaperone for E protein and could prevent premature fusion of E protein during maturation. Recent reports of enhancement of DENV infectivity by anti-prM monoclonal antibodies (mAbs suggest the presence of prM protein in dengue vaccine is potentially harmful. A better understanding of prM-E interaction and its effect on recognition of E and prM proteins by different antibodies would provide important information for future design of safe and effective subunit dengue vaccines. METHODOLOGY/PRINCIPAL FINDINGS: In this study, we examined a series of C-terminal truncation constructs of DENV4 prME, E and prM. In the absence of E protein, prM protein expressed poorly. In the presence of E protein, the expression of prM protein increased in a dose-dependent manner. Radioimmunoprecipitation, sucrose gradient sedimentation and pulse-chase experiments revealed ET1 and EH2 were involved in prM-E interaction and EH2 in maintaining the stability of prM protein. Dot blot assay revealed E protein affected the recognition of prM protein by an anti-prM mAb; truncation of EH2 or EH1 affected the recognition of E protein by several anti-E mAbs, which was further verified by capture ELISA. The E protein ectodomain alone can be recognized well by all anti-E mAbs tested. CONCLUSIONS/SIGNIFICANCE: A C-terminal domain (EH2 of DENV E protein can affect the expression and stability of its chaperone prM protein. These findings not only add to our understanding of the interaction between prM and E proteins, but also suggest the ectodomain of E protein alone could be a potential subunit immunogen without inducing anti-prM response.

  6. A guidebook for the operation and maintenance of HANARO seismic monitoring analysis system

    Energy Technology Data Exchange (ETDEWEB)

    Ryu, Jeong Soo; Yoon, Doo Byung; Kim, Hyung Kyoo

    2003-09-01

    Systems and structures related to HANARO safety are classified as seismic category I. Since 1995, the seismic monitoring system has been utilized for monitoring an earthquake at the HANARO site. The existing seismic monitoring system consists of field sensors and monitoring panel. The analog-type monitoring system with magnetic tape recorder is out-of-date model. In addition, the disadvantage of the existing system is that it does not include signal-analyzing equipment. Therefore, we have improved the analog seismic monitoring system into a new digital Seismic Monitoring Analysis System(SMAS) that can offer precise and detail information of the earthquake signals. This newly developed SMAS is operating at the HANARO instrument room to acquire and analyze the signal of an earthquake. This document is a guidebook for the operation and maintenance of the SMAS. The first chapter gives an outline of the SMAS. The second chapter describes functional capability and specification of the hardware. Chapters 3 and 4 describe starting procedure of the SMAS and how to operate the seismic monitoring program, respectively. Chapter 5 illustrates the seismic analysis algorithm used in the SMAS. The way of operating the seismic analysis program is described in chapter 6. Chapter 7 illustrates the calibration procedure for data acquisition module. Chapter 8 describes the symptoms of common malfunctions and its countermeasure suited to the occasions.

  7. Understanding the functions and operations of data monitoring committees: Survey and focus group findings.

    Science.gov (United States)

    Calis, Karim A; Archdeacon, Patrick; Bain, Raymond P; Forrest, Annemarie; Perlmutter, Jane; DeMets, David L

    2017-02-01

    The use of data monitoring committees in the conduct of clinical trials has increased and evolved, but there is a lack of published information on when data monitoring committees are needed and utilized, the acceptable range of data monitoring committee practices, and appropriate qualifications of data monitoring committee members. To gain a better understanding of data monitoring committee operations and areas for improvement, the Clinical Trials Transformation Initiative conducted a survey and set of focus groups. A total of 143 respondents completed the online survey: 76 data monitoring committee members, 52 sponsors involved with organization of data monitoring committees, and 15 statistical data analysis center representatives. There were 42 focus group participants, including data monitoring committee members; patients and/or patient advocate data monitoring committee members; institutional review board and US Food and Drug Administration representatives; industry, government, and non-profit sponsors; and statistical data analysis center representatives. Participants indicated that the primary responsibility of a data monitoring committee is to be an independent advisory body representing the interests of trial participants by assessing the risk and benefit ratio in ongoing trials. They noted that data monitoring committees must have access to unmasked data in order to perform this role. No clear consensus emerged regarding specific criteria for requiring a data monitoring committee for a given trial, and some participants felt data monitoring committees may be overused. Respondents offered suggestions for the data monitoring committee charter and communications with sponsors, institutional review boards, and regulators. Overall, data monitoring committee members reported that they are able to function independently and their recommendations are almost always accepted by the sponsor. Participants indicated that there are no standards or guidelines pertaining

  8. Condition Monitoring of Machinery in Non-Stationary Operations : Proceedings of the Second International Conference "Condition Monitoring of Machinery in Non-Stationnary Operations"

    CERN Document Server

    Bartelmus, Walter; Chaari, Fakher; Zimroz, Radoslaw; Haddar, Mohamed

    2012-01-01

    Condition monitoring of machines in non-stationary operations (CMMNO) can be seen as the major challenge for research in the field of machinery diagnostics. Condition monitoring of machines in non-stationary operations is the title of the presented book and the title of the Conference held in Hammamet - Tunisia March 26 – 28, 2012. It is the second conference under this title, first took place in Wroclaw - Poland , March 2011. The subject CMMNO comes directly from industry needs and observation of real objects. Most monitored and diagnosed objects used in industry works in non-stationary operations condition. The non-stationary operations come from fulfillment of machinery tasks, for which they are designed for. All machinery used in different kind of mines, transport systems, vehicles like: cars, buses etc, helicopters, ships and battleships and so on work in non-stationary operations. The papers included in the book are shaped by the organizing board of the conference and authors of the papers. The papers...

  9. Computing shifts to monitor ATLAS distributed computing infrastructure and operations

    CERN Document Server

    Bourdarios, Claire; The ATLAS collaboration; Crepe-Renaudin, Sabine Chrystel; De, Kaushik

    2017-01-01

    The ATLAS Distributed Computing (ADC) group established a new Computing Run Coordinator (CRC) shift at the start of LHC Run2 in 2015. The main goal was to rely on a person with a good overview of the ADC activities to ease the ADC experts' workload. The CRC shifter keeps track of ADC tasks related to their fields of expertise and responsibility. At the same time, the shifter maintains a global view of the day-to-day operations of the ADC system. During Run1, this task was accomplished by the ADC Manager on Duty (AMOD), a position that was removed during the shutdown period due to the reduced number and availability of ADC experts foreseen for Run2. The CRC position was proposed to cover some of the AMOD’s former functions, while allowing more people involved in computing to participate. In this way, CRC shifters help train future ADC experts. The CRC shifters coordinate daily ADC shift operations, including tracking open issues, reporting, and representing ADC in relevant meetings. The CRC also facilitates ...

  10. Development of NPP Monitoring and Operation Support Technology

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jung Woon; Park, Jae Chang; Lee, Yong Hee [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)] (and others)

    2008-04-15

    During the first stage (2001.7.1-2004.6.30), we developed general human factors design guidelines VDU-based workstations, PMAS alarm display design guidelines, PMAS SPADES display design guidelines, and the revision of KHNP HFE guidelines (HF-010), which have been applied to domestic NPP designs. We also supported other KNICS projects by performing RPS COM design reviews, development of RPS COM Style Guide, and a review of CEDMCS cabinet operator module display design. We developed the ADIOS prototype, NPP performance analysis systems for YGN No.1, 2 plants and Kori No. 2 plant, alarm cause tracking systems for Kori No. 2 plant and OPR1000, and signal fault detection and diagnosis methods for deaerators and steam generators. During the second stage(2004.7.1-2008.4.30), we supported other KNICS projects by reviewing RPS COM display designs three times, developing ESF-CCS COM style guides and reviewing ESF-CCS COM display design, reviewing CRCS LOM and PCS MTP display designs, and developing requirements for DCS GUI components. We also developed integrated style guide for I and C cabinet operator module display designs. In cooperative research with KOPEC-AE, we developed basic technologies for advanced HSI design including task analysis methods, an information and control requirements database, display design criteria, a HSI prototype with its evaluation, and methods for human factors engineering verification and validation.

  11. Computing shifts to monitor ATLAS distributed computing infrastructure and operations

    CERN Document Server

    Adam Bourdarios, Claire; The ATLAS collaboration

    2016-01-01

    The ATLAS Distributed Computing (ADC) group established a new Computing Run Coordinator (CRC) shift at the start of LHC Run2 in 2015. The main goal was to rely on a person with a good overview of the ADC activities to ease the ADC experts' workload. The CRC shifter keeps track of ADC tasks related to their fields of expertise and responsibility. At the same time, the shifter maintains a global view of the day-to-day operations of the ADC system. During Run1, this task was accomplished by the ADC Manager on Duty (AMOD), a position that was removed during the shutdown period due to the reduced number and availability of ADC experts foreseen for Run2. The CRC position was proposed to cover some of the AMOD’s former functions, while allowing more people involved in computing to participate. In this way, CRC shifters help train future ADC experts. The CRC shifters coordinate daily ADC shift operations, including tracking open issues, reporting, and representing ADC in relevant meetings. The CRC also facilitates ...

  12. Geodetic Monitoring System Operating On Neapolitan Volcanic Area (southern Italy)

    Science.gov (United States)

    Pingue, F.; Ov-Geodesy Team

    The Neapolitan volcanic area is located in the southern sector of the Campanian Plain Graben including three volcanic active structures (Somma-Vesuvius, Campi Flegrei and Ischia). The Somma-Vesuvius complex, placed East of Naples, is a strato-volcano composed by a more ancient apparatus (Mt. Somma) and a younger cone (Mt. Vesu- vius) developed inside Somma caldera. Since last eruption (1944) it is in a quiescent state characterised by a low level seismicity and deformation activity. The Campi Fle- grei, located West of Naples, are a volcanic field inside an older caldera rim. The last eruption, occurred in the 1538, built up the Mt. Nuovo cone. The Campi Flegrei are subject to a slow vertical deformation, called bradyseism. In the 1970-1972 and 1982-1984 they have been affected by two intense episodes of ground upheaval (ac- companied by an intense seismic activity)0, followed by a subsidence phase, slower than uplift and still active. Though such phenomenon has not been followed by erup- tive events, it caused serious damages, emphasizing the high volcanic risk of the phle- grean caldera. The Ischia island, located SW of Naples, has been characterised by a volcanic activity both explosive and effusive, occurred mainly in the last 50,000 years. These events modelled the topography producing fault systems and structures delim- iting the Mt. Epomeo resurgent block. The last eruption has occurred on 1302. After, the dynamics of the island has been characterised by seismic activity (the strongest earthquake occurred on 1883) and by a meaningful subsidence, on the S and NW sec- tors of the island. The concentration of such many active volcanoes in an area with a dense urbanization (about 1,500,000 inhabitants live) needs systematic and contin- uous monitoring of the dynamics. These information are necessary in order to char- acterise eruptive precursors useful for modelling the volcanoes behaviour. Insofar, the entire volcanic Neapolitan area, characterised by a

  13. SIMONS: Ship Monitoring System Support Tactical and Operational Missions

    Science.gov (United States)

    Margarit, Gerard

    2016-08-01

    This paper presents the latest results that have been obtained by GMV in the Maritime Surveillance and Awareness (MSA) domain through the exploitation of the SIMONS suite within fully operational scenarios. Diversified actors have been interacted with from pure public authorities to pure private companies for different specific goals. Scenario conditions were also varying in terms of area and target of interest, input data sources, ancillary datasets and dissemination strategies. The results show that SIMONS is a very useful tool in MSA that can complement the tactical and strategic information that can be obtained through in-situ and classical surveillance means (airborne- and ship-based visual reconnaissance...). Beyond timely delivery of reports, the capability to detect small non-metallic targets and to categorize most of the detected spots are two of the most prominent and recognized features.

  14. Methodology of "Physical and Rehabilitation Medicine practice, Evidence Based Position Papers: the European position" produced by the UEMS-PRM Section.

    Science.gov (United States)

    Negrini, Stefano; Kiekens, Carlotte; Zampolini, Mauro; Wever, Daniel; Varela Donoso, Enrique; Christodoulou, Nicolas

    2016-02-01

    Since 2009 the Professional Practice Committee of the Physical and Rehabilitation Medicine (PRM) Section of the European Union (EU) of Medical Specialists (UEMS) is producing Position Papers (PPs) on the role of PRM physicians for patients with different health conditions or related topics of PRM Interest. These PPs represent the Official Position of the EU in the specific field. Until now, sixteen papers have been produced, recently collected in an e-book. To proceed with the future PPs, the UEMS PRM Section defines with this paper the methodological approach to a PP, so to have a common and validated scientific structure. The final aim is to increase the quality, representativeness and visibility of this production for the benefit of all PRM specialists in (and out) of Europe. The Position Papers must be Evidence Based (EBPP). Therefore it comprises a systematic review as well as a Consensus procedure among the EU Countries delegates. All the sections of an EBPP are presented in details (title, authors, abstract, introduction, material and methods, results, discussion, conclusion). The systematic review must focus on Cochrane reviews, randomised controlled trials and guidelines of PRM professional practice interest. The Consensus on the recommendations must be reached through a Delphi procedure, usually in four major rounds (each round can have repeated voting). The EBPP must produce Final Recommendations for Physical and Rehabilitation Medicine Professional Practice in Europe. The following overall structure for recommendations is suggested: one overall general recommendation on PRM professional practice; PRM physicians' role in Medical Diagnosis - ICD; PRM diagnosis and assessment according to ICF; PRM process (Project definition, Team, PRM interventions, Outcome criteria, Length and continuity of treatment); future research on PRM professional practice.

  15. The Saccharomyces cerevisiae PRM1 homolog in Neurospora crassa is involved in vegetative and sexual cell fusion events but also has postfertilization functions.

    Science.gov (United States)

    Fleissner, André; Diamond, Spencer; Glass, N Louise

    2009-02-01

    Cell-cell fusion is essential for a variety of developmental steps in many eukaryotic organisms, during both fertilization and vegetative cell growth. Although the molecular mechanisms associated with intracellular membrane fusion are well characterized, the molecular mechanisms of plasma membrane merger between cells are poorly understood. In the filamentous fungus Neurospora crassa, cell fusion events occur during both vegetative and sexual stages of its life cycle, thus making it an attractive model for studying the molecular basis of cell fusion during vegetative growth vs. sexual reproduction. In the unicellular yeast Saccharomyces cerevisiae, one of the few proteins implicated in plasma membrane merger during mating is Prm1p; prm1Delta mutants show an approximately 50% reduction in mating cell fusion. Here we report on the role of the PRM1 homolog in N. crassa. N. crassa strains with deletions of a Prm1-like gene (Prm1) showed an approximately 50% reduction in both vegetative and sexual cell fusion events, suggesting that PRM1 is part of the general cell fusion machinery. However, unlike S. cerevisiae, N. crassa strains carrying a Prm1 deletion exhibited complete sterility as either a male or female mating partner, a phenotype that was not complemented in a heterokaryon with wild type (WT). Crosses with DeltaPrm1 strains were blocked early in sexual development, well before development of ascogenous hyphae. The DeltaPrm1 sexual defect in N. crassa was not suppressed by mutations in Sad-1, which is required for meiotic silencing of unpaired DNA (MSUD). However, mutations in Sad-1 increased the number of progeny obtained in crosses with a DeltaPrm1 (Prm1-gfp) complemented strain. These data indicate multiple roles for PRM1 during sexual development.

  16. Computer monitors and controls all truck-shovel operations

    Energy Technology Data Exchange (ETDEWEB)

    Chironis, N.P.

    1985-03-01

    The intense competition in the coal industry and the advances in computer technology have led several large mines to consider computer dispatching systems as a means of optimizing production. Quintette Coal, Ltd., of Vancouver, B.C., has engaged Modular Mining Systems, Inc., of Tucson, to install a comprehensive truck-dispatch system at a new, multiseam mine northeast of Vancouver. This open-pit operation will rely on truck-shovel teams to uncover both steam and metallurgical coal. The mine is already using about 12 shovels and 50 trucks to produce 3 million tpy. By 1986, production will hit 5 million tpy of metallurgical coal and 1.3 million tpy of steam coal. The coal is under contract to be shipped to Japan. Denison Mines Ltd., owns 50% of Quintette Coal. Of the other 14 shareholders, 10 are Japanese steel companies. Although about 10 non-coal mines worldwide are using some form of computer-controlled dispatching system, Quintette is the first coal company to do so and western US mines are reportedly studying the Quintette system carefully.

  17. Operational-Condition-Independent Criteria Dedicated to Monitoring Wind Turbine Generators: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Yang, W.; Sheng, S.; Court, R.

    2012-08-01

    To date the existing wind turbine condition monitoring technologies and commercially available systems have not been fully accepted for improving wind turbine availability and reducing their operation and maintenance costs. One of the main reasons is that wind turbines are subject to constantly varying loads and operate at variable rotational speeds. As a consequence, the influences of turbine faults and the effects of varying load and speed are coupled together in wind turbine condition monitoring signals. So, there is an urgent need to either introduce some operational condition de-coupling procedures into the current wind turbine condition monitoring techniques or develop a new operational condition independent wind turbine condition monitoring technique to maintain high turbine availability and achieve the expected economic benefits from wind. The purpose of this paper is to develop such a technique. In the paper, three operational condition independent criteria are developed dedicated for monitoring the operation and health condition of wind turbine generators. All proposed criteria have been tested through both simulated and practical experiments. The experiments have shown that these criteria provide a solution for detecting both mechanical and electrical faults occurring in wind turbine generators.

  18. Monitoring System for Farming Operations with Wearable Devices Utilized Sensor Networks

    Directory of Open Access Journals (Sweden)

    Tokihiro Fukatsu

    2009-08-01

    Full Text Available In order to automatically monitor farmers’ activities, we propose a farm operation monitoring system using “Field Servers” and a wearable device equipped with an RFID reader and motion sensors. Our proposed system helps in recognizing farming operations by analyzing the data from the sensors and detected RFID tags that are attached to various objects such as farming materials, facilities, and machinery. This method can be applied to various situations without changing the conventional system. Moreover, this system provides useful information in real-time and controls specific machines in a coordinated manner on the basis of recognized operation.

  19. Monitoring System for Farming Operations with Wearable Devices Utilized Sensor Networks

    Science.gov (United States)

    Fukatsu, Tokihiro; Nanseki, Teruaki

    2009-01-01

    In order to automatically monitor farmers’ activities, we propose a farm operation monitoring system using “Field Servers” and a wearable device equipped with an RFID reader and motion sensors. Our proposed system helps in recognizing farming operations by analyzing the data from the sensors and detected RFID tags that are attached to various objects such as farming materials, facilities, and machinery. This method can be applied to various situations without changing the conventional system. Moreover, this system provides useful information in real-time and controls specific machines in a coordinated manner on the basis of recognized operation. PMID:22454578

  20. Installation and Operation of RENO Slow Control and Online Monitoring System

    CERN Document Server

    Choi, J H; Pac, M Y; Ahn, J K; Choi, S; Choi, Y; Choi, W K; Jang, J S; Jeon, E J; Joo, K K; Kim, H S; Kim, J Y; Kim, S B; Kim, W; Kim, Y D; Lee, J; Lim, I T; Ma, K J; Park, I G; Park, J S; Park, K S; Shin, J W; K, Siyeon; Stepanyan, S S; Yeo, I S; Yu, I

    2013-01-01

    The RENO is the reactor based experiment to measure the smallest neutrino mixing angle, $\\theta_{13}$. The slow control and online monitoring system for RENO monitors the status of the HV systems, the temperatures of the electronics crates and detectors, the fluids levels, humidities of experimental halls and electronics huts, and gas concentrations. And the slow control system is able to set up high voltage for each channel and turn on and off HV remotely. An online monitoring system located in the control room reads data from the DAQ host computer via network. It provides event display, online histograms to monitor detector performance, and variety of additional tasks needed to efficiently monitor detector performance parameters and diagnose troubles of detector and DAQ system. In this paper, we explan the installation of the slow control and monitoring system and their operation status,

  1. PRM:Partner Relationship Management In the New Economic Times%PRM:新经济时代的伙伴关系管理

    Institute of Scientific and Technical Information of China (English)

    叶晓松; 韦司滢

    2004-01-01

    伙伴关系管理(PRM)是为了更好地管理公司销售渠道和分销商的需要而建立的,根据其通过与渠道伙伴的接触以及从相应合同中所获得的有关渠道伙伴的信息,对它们进行分类管理并加以利用的软件系统,探讨了PRM与CRM的关系、PRM的功能、PRM的分析框架及其实现的技术手段和应用前景.

  2. Feasibility Study of a Rotorcraft Health and Usage Monitoring System (HUMS): Results of Operator's Evaluation

    Science.gov (United States)

    Romero, Raylund; Summers, Harold; Cronkhite, James

    1996-01-01

    The objective was to evaluate the feasibility of a state-of-the-art health and usage monitoring system (HUMS) to provide monitoring of critical mechanical systems on the helicopter, including motors, drive train, engines, and life-limited components. The implementation of HUMS and cost integration with current maintenance procedures was assessed from the operator's viewpoint in order to achieve expected benefits from these systems, such as enhanced safety, reduced maintenance cost, and increased availability. An operational HUMS that was installed and operated under an independent flight trial program was used as a basis for this study. The HUMS equipment and software were commercially available. Based on the results of the feasibility study, the HUMS used in the flight trial program generally demonstrated a high level of reliability in monitoring the rotor system, engines, drive train, and life-limited components. The system acted as a sentinel to warn of impending failures. A worn tail rotor pitch bearing was detected by HUMS, which had the capability for self testing to diagnose system and sensor faults. Examples of potential payback to the operator with HUMS were identified, including reduced insurance cost through enhanced safety, lower operating costs derived from maintenance credits, increased aircraft availability, and improved operating efficiency. The interfacing of HUMS with current operational procedures was assessed to require only minimal revisions to the operator's maintenance manuals. Finally the success in realizing the potential benefits from HUMS technology was found to depend on the operator, helicopter manufacturer, regulator (FAA), and HUMS supplier working together.

  3. General Purpose Data-Driven Online System Health Monitoring with Applications to Space Operations

    Science.gov (United States)

    Iverson, David L.; Spirkovska, Lilly; Schwabacher, Mark

    2010-01-01

    Modern space transportation and ground support system designs are becoming increasingly sophisticated and complex. Determining the health state of these systems using traditional parameter limit checking, or model-based or rule-based methods is becoming more difficult as the number of sensors and component interactions grows. Data-driven monitoring techniques have been developed to address these issues by analyzing system operations data to automatically characterize normal system behavior. System health can be monitored by comparing real-time operating data with these nominal characterizations, providing detection of anomalous data signatures indicative of system faults, failures, or precursors of significant failures. The Inductive Monitoring System (IMS) is a general purpose, data-driven system health monitoring software tool that has been successfully applied to several aerospace applications and is under evaluation for anomaly detection in vehicle and ground equipment for next generation launch systems. After an introduction to IMS application development, we discuss these NASA online monitoring applications, including the integration of IMS with complementary model-based and rule-based methods. Although the examples presented in this paper are from space operations applications, IMS is a general-purpose health-monitoring tool that is also applicable to power generation and transmission system monitoring.

  4. Quantitative comparison of operative skill using 2- and 3-dimensional monitors during laparoscopic phantom tasks.

    Science.gov (United States)

    Nishi, Masayasu; Kanaji, Shingo; Otake, Yoshito; Harada, Hitoshi; Yamamoto, Masashi; Oshikiri, Taro; Nakamura, Tetsu; Suzuki, Satoshi; Suzuki, Yuki; Hiasa, Yuta; Sato, Yoshinobu; Kakeji, Yoshihiro

    2017-05-01

    The recent development of stereoscopic images using 3-dimensional monitors is expected to improve techniques for laparoscopic operation. Several studies have reported technical advantages in using 3-dimensional monitors with regard to operative accuracy and working speed, but there are few reports that analyze forceps motions by 3-dimensional optical tracking systems during standardized laparoscopic phantom tasks. We attempted to develop a 3-dimensional motion analysis system for assessing laparoscopic tasks and to clarify the efficacy of using stereoscopic images from a 3-dimensional monitor to track forceps movement during laparoscopy. Twenty surgeons performed 3 tasks (Task 1: a simple operation by the dominant hand, Task 2: a simple operation using both hands, Task 3: a complicated operation using both hands) under 2-dimensional and 3-dimensional systems. We tracked and recorded the motion of forceps tips with an optical marker captured by a 3-dimensional position tracker. We analyzed factors such as forceps path lengths, operation times, and technical errors for each task and compared the results of 2-dimensional and 3-dimensional monitors. Mean operation times and technical errors were improved significantly for all tasks performed under the 3-dimensional system compared with the 2-dimensional system; in addition, mean path lengths for the forceps tips were shorter for all tasks performed under the 3-dimensional system. We found that stereoscopic images using a 3-dimensional monitor improved operative techniques with regard to increased accuracy and shorter path lengths for forceps movement, which resulted in a shorter operation time for basic phantom laparoscopic tasks. Copyright © 2016 Elsevier Inc. All rights reserved.

  5. Characterization of the GXXXG motif in the first transmembrane segment of Japanese encephalitis virus precursor membrane (prM) protein.

    Science.gov (United States)

    Lin, Ying-Ju; Peng, Jia-Guan; Wu, Suh-Chin

    2010-05-24

    The interaction between prM and E proteins in flavivirus-infected cells is a major driving force for the assembly of flavivirus particles. We used site-directed mutagenesis to study the potential role of the transmembrane domains of the prM proteins of Japanese encephalitis virus (JEV) in prM-E heterodimerization as well as subviral particle formation. Alanine insertion scanning mutagenesis within the GXXXG motif in the first transmembrane segment of JEV prM protein affected the prM-E heterodimerization; its specificity was confirmed by replacing the two glycines of the GXXXG motif with alanine, leucine and valine. The GXXXG motif was found to be conserved in the JEV serocomplex viruses but not other flavivirus groups. These mutants with alanine inserted in the two prM transmembrane segments all impaired subviral particle formation in cell cultures. The prM transmembrane domains of JEV may play importation roles in prM-E heterodimerization and viral particle assembly.

  6. Environmental Monitoring Plan United States Department of Energy Richland Operations Office. Revision 2

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-11-10

    This Environmental Monitoring Plan was prepared for the US Department of Energy`s (DOE`s) Richland Operations Office (RL) to implement the requirements of DOE Order 5400.1. According to the Order, each DOE site, facility, or activity that uses, generates, releases, or manages significant pollutants or hazardous materials shall prepare a written environmental monitoring plan covering two major activities: (1) effluent monitoring and (2) environmental surveillance. The plan is to contain information discussing the rationale and design criteria for the monitoring programs, sampling locations and schedules, quality assurance requirements, program implementation procedures, analytical procedures, and reporting requirements. The plan`s purpose is to assist DOE in the management of environmental activities at the Hanford Site and to help ensure that operations on the site are conducted in an environmentally safe and sound manner.

  7. 4th International Conference on Condition Monitoring of Machinery in Non-Stationary Operations

    CERN Document Server

    Zimroz, Radoslaw; Bartelmus, Walter; Haddar, Mohamed

    2016-01-01

    The book provides readers with a snapshot of recent research and technological trends in the field of condition monitoring of machinery working under a broad range of operating conditions. Each chapter, accepted after a rigorous peer-review process, reports on an original piece of work presented and discussed at the 4th International Conference on Condition Monitoring of Machinery in Non-stationary Operations, CMMNO 2014, held on December 15-16, 2014, in Lyon, France. The contributions have been grouped into three different sections according to the main subfield (signal processing, data mining, or condition monitoring techniques) they are related to. The book includes both theoretical developments as well as a number of industrial case studies, in different areas including, but not limited to: noise and vibration; vibro-acoustic diagnosis; signal processing techniques; diagnostic data analysis; instantaneous speed identification; monitoring and diagnostic systems; and dynamic and fault modeling. This book no...

  8. Operational-Condition-Independent Criteria Dedicated to Monitoring Wind Turbine Generators

    Directory of Open Access Journals (Sweden)

    Richard Court

    2013-01-01

    Full Text Available Condition monitoring is beneficial to the wind industry for both onshore and offshore plants. However, due to the variations in operational conditions, its potential has not been fully explored. There is a need to develop an operational-condition-independent condition monitoring technique, which has motivated the research presented here. In this paper, three operational-condition-independent criteria are developed. The criteria accomplish the condition monitoring by analyzing the wind turbine electrical signals in the time domain. Therefore, they are simple to calculate and ideal for online use. All proposed criteria were tested through both simulated and practical experiments. The experiments have shown that these criteria not only provide a solution for detecting both mechanical and electrical faults that occur in wind turbine generators, but provide a potential tool for diagnosing generator winding faults.

  9. Immune response to synthetic peptides of dengue prM protein.

    Science.gov (United States)

    Vázquez, Susana; Guzmán, María Guadalupe; Guillen, Gerardo; Chinea, Glay; Pérez, Ana Beatriz; Pupo, Maritza; Rodriguez, Rosmary; Reyes, Osvaldo; Garay, Hilda Elisa; Delgado, Iselys; García, Gissel; Alvarez, Mayling

    2002-03-15

    The immunological activities of five synthetic peptides of the prM protein of dengue-2 (DEN-2) virus containing B cell epitopes were evaluated in BALB/c mice. Two peptides elicited neutralizing antibodies against all four DEN serotypes. Virus-specific proliferative responses were demonstrated in mice immunized with four of the five peptides, demonstrating the presence of T cell epitopes. Mice immunized with three of the five peptides conjugated with bovine albumin showed statistically significant levels (Pdevelopment of anti-flaviviral vaccines.

  10. Design, calibration, and operation of 220Rn stack effluent monitoring systems at Argonne National Laboratory.

    Science.gov (United States)

    Munyon, W J; Kretz, N D; Marchetti, F P

    1994-09-01

    A group of stack effluent monitoring systems have been developed to monitor discharges of 220Rn from a hot cell facility at Argonne National Laboratory. The stack monitors use flow-through scintillation cells and are completely microprocessor-based systems. A method for calibrating the stack monitors in the laboratory and in the field is described. A nominal calibration factor for the stack monitoring systems in use is 15.0 cts min-1 per kBq m-3 (0.56 cts min-1 per pCi L-1) +/- 26% at the 95% confidence level. The plate-out fraction of decay products in the stack monitor scintillation cells, without any pre-filtering, was found to be nominally 25% under normal operating conditions. When the sample was pre-filtered upstream of the scintillation cell, the observed cell plate-out fraction ranged from 16-22%, depending on the specific sampling conditions. The instantaneous 220Rn stack concentration can be underestimated or overestimated when the steady state condition established between 220Rn and its decay products in the scintillation cell is disrupted by sudden changes in the monitored 220Rn concentration. For long-term measurements, however, the time-averaged response of the monitor represents the steady state condition and leads to a reasonable estimate of the average 220Rn concentration during the monitoring period.

  11. 40 CFR 60.3039 - How do I make sure my continuous emission monitoring systems are operating correctly?

    Science.gov (United States)

    2010-07-01

    ... emission monitoring systems are operating correctly? 60.3039 Section 60.3039 Protection of Environment... emission monitoring systems are operating correctly? (a) Conduct initial, daily, quarterly, and annual evaluations of your continuous emission monitoring systems that measure carbon monoxide and oxygen....

  12. 40 CFR 60.1240 - How do I make sure my continuous emission monitoring systems are operating correctly?

    Science.gov (United States)

    2010-07-01

    ... emission monitoring systems are operating correctly? 60.1240 Section 60.1240 Protection of Environment... Continuous Emission Monitoring § 60.1240 How do I make sure my continuous emission monitoring systems are operating correctly? (a) Conduct initial, daily, quarterly, and annual evaluations of your...

  13. 40 CFR 60.2940 - How do I make sure my continuous emission monitoring systems are operating correctly?

    Science.gov (United States)

    2010-07-01

    ... emission monitoring systems are operating correctly? 60.2940 Section 60.2940 Protection of Environment... monitoring systems are operating correctly? (a) Conduct initial, daily, quarterly, and annual evaluations of your continuous emission monitoring systems that measure carbon monoxide and oxygen. (b) Complete...

  14. 40 CFR 60.1730 - How do I make sure my continuous emission monitoring systems are operating correctly?

    Science.gov (United States)

    2010-07-01

    ... emission monitoring systems are operating correctly? 60.1730 Section 60.1730 Protection of Environment... continuous emission monitoring systems are operating correctly? (a) Conduct initial, daily, quarterly, and annual evaluations of your continuous emission monitoring systems that measure oxygen (or carbon...

  15. 40 CFR 62.15185 - How do I make sure my continuous emission monitoring systems are operating correctly?

    Science.gov (United States)

    2010-07-01

    ... emission monitoring systems are operating correctly? 62.15185 Section 62.15185 Protection of Environment... make sure my continuous emission monitoring systems are operating correctly? (a) Conduct initial, daily, quarterly, and annual evaluations of your continuous emission monitoring systems that measure oxygen...

  16. Significance of Operating Environment in Condition Monitoring of Large Civil Structures

    Directory of Open Access Journals (Sweden)

    Sreenivas Alampalli

    1999-01-01

    Full Text Available Success of remote long-term condition monitoring of large civil structures and developing calibrated analytical models for damage detection, depend significantly on establishing accurate baseline signatures and their sensitivity. Most studies reported in the literature concentrated on the effect of structural damage on modal parameters without emphasis on reliability of modal parameters. Thus, a field bridge structure was studied for the significance of operating conditions in relation to baseline signatures. Results indicate that in practice, civil structures should be monitored for at least one full cycle of in-service environmental changes before establishing baselines for condition monitoring or calibrating finite-element models. Boundary conditions deserve special attention.

  17. PHYSIOLOGICAL MONITORING OPERATORS ACS IN AUDIO-VISUAL SIMULATION OF AN EMERGENCY

    Directory of Open Access Journals (Sweden)

    S. S. Aleksanin

    2010-01-01

    Full Text Available In terms of ship simulator automated control systems we have investigated the information content of physiological monitoring cardiac rhythm to assess the reliability and noise immunity of operators of various specializations with audio-visual simulation of an emergency. In parallel, studied the effectiveness of protection against the adverse effects of electromagnetic fields. Monitoring of cardiac rhythm in a virtual crash it is possible to differentiate the degree of voltage regulation systems of body functions of operators on specialization and note the positive effect of the use of means of protection from exposure of electromagnetic fields.

  18. The ATLAS Trigger Monitoring and Operations in proton-proton collisions

    CERN Document Server

    The ATLAS collaboration

    2010-01-01

    With the first proton-proton collisions at $\\sqrt{s}=900~\\mathrm{GeV}$ in December 2009, the full chain of the ATLAS Trigger and Data Acquisition system could be tested with real conditions for the first time. Monitoring the performance and operation of these systems required a smooth and parallel running of many complex software tools depending on each other. They are the basis of rate measurements, data quality determination of selected objects and supervision of the system during the data taking. Based on the successful data taking experience with first collisions, the ATLAS trigger monitoring and operations performance are described.

  19. RCRA and operational monitoring 1994 fiscal year work plan, WBS 1.5.3

    Energy Technology Data Exchange (ETDEWEB)

    1993-12-01

    RCRA & Operational Monitoring (ROM) Program Office manages the direct funded Resource Conservation Recovery Act (RCRA) and Operational Monitoring under Work Breakdown Structure (WBS) 1.5.3. The ROM Program Office is a Branch of liquid Waste Disposal, a part of Restoration and Remediation of Westinghouse Hanford Company (WHC). The Fiscal Year Work Plan (FYWP) takes it direction from the Multi-Year Program Plan (MYPP). The FYWP provides the near term, enhanced details for the Program Office to use as baseline Cost, Scope and Schedule. Changs Control administered during the fiscal year is against the baseline provided by the FYWP.

  20. A single N-linked glycosylation site in the Japanese encephalitis virus prM protein is critical for cell type-specific prM protein biogenesis, virus particle release, and pathogenicity in mice.

    Science.gov (United States)

    Kim, Jeong-Min; Yun, Sang-Im; Song, Byung-Hak; Hahn, Youn-Soo; Lee, Chan-Hee; Oh, Hyun-Woo; Lee, Young-Min

    2008-08-01

    The prM protein of Japanese encephalitis virus (JEV) contains a single potential N-linked glycosylation site, N(15)-X(16)-T(17), which is highly conserved among JEV strains and closely related flaviviruses. To investigate the role of this site in JEV replication and pathogenesis, we manipulated the RNA genome by using infectious JEV cDNA to generate three prM mutants (N15A, T17A, and N15A/T17A) with alanine substituting for N(15) and/or T(17) and one mutant with silent point mutations introduced into the nucleotide sequences corresponding to all three residues in the glycosylation site. An analysis of these mutants in the presence or absence of endoglycosidases confirmed the addition of oligosaccharides to this potential glycosylation site. The loss of prM N glycosylation, without significantly altering the intracellular levels of viral RNA and proteins, led to an approximately 20-fold reduction in the production of extracellular virions, which had protein compositions and infectivities nearly identical to those of wild-type virions; this reduction occurred at the stage of virus release, rather than assembly. This release defect was correlated with small-plaque morphology and an N-glycosylation-dependent delay in viral growth. A more conservative mutation, N15Q, had the same effect as N15A. One of the four prM mutants, N15A/T17A, showed an additional defect in virus growth in mosquito C6/36 cells but not human neuroblastoma SH-SY5Y or hamster BHK-21 cells. This cell type dependence was attributed to abnormal N-glycosylation-independent biogenesis of prM. In mice, the elimination of prM N glycosylation resulted in a drastic decrease in virulence after peripheral inoculation. Overall, our findings indicate that this highly conserved N-glycosylation motif in prM is crucial for multiple stages of JEV biology: prM biogenesis, virus release, and pathogenesis.

  1. A technical system to improve the operational monitoring of the Zaporozhye nuclear power plant

    Energy Technology Data Exchange (ETDEWEB)

    Beyer, M.; Carl, H.; Nowak, K. [Technischer Ueberwachungsverein Rheinland, Koeln (Germany). Inst. for Nuclear Engineering and Radiation Protection; Schumann, P.; Seidel, A.; Weiss, F.P.; Zschau, J.

    1998-10-01

    As part of the programme implemented by the German Ministry of Environment, Nature Conservation and Reactor Safety to cooperate with the Central and Eastern European States (CEES) and the Commonwealth of Independent States (CIS) in the area of nuclear safety, a technical system to improve operational monitoring has been designed, specified and established since 1992 as a pilot project in the Zaporozhye/Ukraine nuclear power plant by Forschungszentrum Rossendorf and Technischer Ueberwachungsverein Rheinland with a significant contribution from the State Scientific and Technical Centre of the Ukrainian supervisory authority. The technical system complements existing operational checking and monitoring facilities by including modern means of information technology. It enables a continuous monitoring of the state of unit 5 in normal operation and in cases of anomalies or incidents so that when recognisable deviations from the regular plant operation occur, the Ukrainian supervisory authority can immediately inquire and if necessary impose conditions on the operator. The radiological and meteorological parameters at the nuclear power plant location are monitored to the extent necessary to assess the current radiation situation and to implement efficient emergency management measures. (orig.)

  2. Data Processing Concepts for the Integration of SAR Into Operational Volcano Monitoring Systems

    Science.gov (United States)

    Meyer, F. J.; McAlpin, D. B.; Gong, W.; Arko, S.; Webley, P. W.; Dehn, J.

    2013-05-01

    Remote Sensing plays a critical role in operational volcano monitoring due to the often remote locations of volcanic systems and the large spatial extent of potential eruption pre-cursor signals. Despite the all-weather capabilities of radar remote sensing and despite its high performance in monitoring change, the contribution of radar data to operational monitoring activities has been limited in the past. This is largely due to (1) the high data costs associated with radar data, (2) the slow data processing and delivery procedures, and (3) the limited temporal sampling provided by spaceborne radars. With this paper, we present new data processing and data integration techniques that mitigate some of the above mentioned limitations and allow for a meaningful integration of radar remote sensing data into operational volcano monitoring systems. The data integration concept presented here combines advanced data processing techniques with fast data access procedures in order to provide high quality radar-based volcano hazard information at improved temporal sampling rates. First performance analyses show that the integration of SAR can significantly improve the ability of operational systems to detect eruptive precursors. Therefore, the developed technology is expected to improve operational hazard detection, alerting, and management capabilities.

  3. Expression of recombinant West Nile virus prM protein fused to an affinity tag for use as a diagnostic antigen.

    Science.gov (United States)

    Setoh, Y X; Hobson-Peters, J; Prow, N A; Young, P R; Hall, R A

    2011-07-01

    Previous studies have concluded that the Flavivirus prM protein is a suitable viral antigen to distinguish serologically between infections with closely related Flaviviruses (Cardosa et al., 2002). To express the recombinant West Nile virus (WNV) prM antigen fused to a suitable affinity tag for purification, a series of prM-His-tag and prM-V5-tag fusion proteins were generated. Analysis of the prM-His-tag fusion proteins revealed that either prM epitopes were disrupted or the His-tag was not presented properly depending on the location of the His tag and the presence of the prM transmembrane domains in these constructs. This identified domains critical for proper folding of prM, and arrangements that allowed the correct presentation of the His-tag. However, the inclusion of the V5 epitope tag fused to the C terminus of prM allowed formation of the authentic antigenic structure of prM and the proper presentation of the V5 epitope. Capture of tagged recombinant WNV(NY99) prM antigen to the solid phase with anti-V5 antibody in ELISA enabled the detection of prM-specific antibodies in WNV(NY99)-immune horse serum, confirming its potential as a useful diagnostic reagent.

  4. 杜比PRM-4200专业视频效果测试校正仪

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    杜比PRM-4200是首款基于平板的测试校正仪,能够精确地呈现真正的黑电平,整个色域具有卓越的暗部细节和更高的对比度。杜比PRM-4200的背光包含超过4,500个红、绿、蓝组合的独立发光二极管(LED)。

  5. Integrating SAR and derived products into operational volcano monitoring and decision support systems

    Science.gov (United States)

    Meyer, F. J.; McAlpin, D. B.; Gong, W.; Ajadi, O.; Arko, S.; Webley, P. W.; Dehn, J.

    2015-02-01

    Remote sensing plays a critical role in operational volcano monitoring due to the often remote locations of volcanic systems and the large spatial extent of potential eruption pre-cursor signals. Despite the all-weather capabilities of radar remote sensing and its high performance in monitoring of change, the contribution of radar data to operational monitoring activities has been limited in the past. This is largely due to: (1) the high costs associated with radar data; (2) traditionally slow data processing and delivery procedures; and (3) the limited temporal sampling provided by spaceborne radars. With this paper, we present new data processing and data integration techniques that mitigate some of these limitations and allow for a meaningful integration of radar data into operational volcano monitoring decision support systems. Specifically, we present fast data access procedures as well as new approaches to multi-track processing that improve near real-time data access and temporal sampling of volcanic systems with SAR data. We introduce phase-based (coherent) and amplitude-based (incoherent) change detection procedures that are able to extract dense time series of hazard information from these data. For a demonstration, we present an integration of our processing system with an operational volcano monitoring system that was developed for use by the Alaska Volcano Observatory (AVO). Through an application to a historic eruption, we show that the integration of SAR into systems such as AVO can significantly improve the ability of operational systems to detect eruptive precursors. Therefore, the developed technology is expected to improve operational hazard detection, alerting, and management capabilities.

  6. Osteoporosis. The role of physical and rehabilitation medicine physicians. The European perspective based on the best evidence. A paper by the UEMS-PRM Section Professional Practice Committee.

    Science.gov (United States)

    Oral, A; Küçükdeveci, A A; Varela, E; Ilieva, E M; Valero, R; Berteanu, M; Christodoulou, N

    2013-08-01

    One of the objectives of the Professional Practice Committee (PPC) of the Physical and Rehabilitation Medicine (PRM) Section of the Union of European Medical Specialists (UEMS) is the development of the field of competence of PRM physicians in Europe. To achieve this objective, UEMS PRM Section PPC has adopted a systematic action plan of preparing a series of papers describing the role of PRM physicians in a number of disabling health conditions, based on the evidence of effectiveness of PRM interventions. A wide range of health conditions treated by PRM specialists carries the risk of osteoporosis (OP). The consequences of OP may be associated with significant disability. The aim of this paper is: to define the role of PRM physicians in the prevention and management of OP, to describe the needs of people with OP in relation to rehabilitation strategy, and to highlight why and how PRM physicians should be involved in the diagnosis and management of OP. PRM physicians may intervene in the prevention of and risk factor assessment for OP, falls and fractures along with other assessments of functioning and of quality of life. In addition, they are involved in diagnosis and in both pharmacological and nonpharmacological treatment of OP. From a specific PRM perspective based on the International Classification of Functioning, Disability and Health (ICF), there is an important role in optimizing functioning and promoting "activities and participation", including interventions associated with environmental factors for people with OP or osteoporotic fractures. Evidence suggests that a large number of interventions within the scope of PRM that range from preventive strategies (including education and self management and most importantly exercise) to pain management strategies and spinal orthoses or hip protectors may be effective in the prevention and/or management of OP and its sequelae. Competencies and aptitudes of PRM specialists, focusing especially on functioning while

  7. Towards the development of integrated monitoring system for retreat mining operations

    Institute of Scientific and Technical Information of China (English)

    HAMID Maleki

    2008-01-01

    Through cooperative research between the government, the private sector,mining companies and equipment manufacturers, considerable progress had been madeduring the last decade in studying the mechanics of strata failure and acquiring the know-ledge needed to develop an integrated monitoring system for assessing local roof stability.Because of higher geotechnical risks in retreat mining operations, it was both important todevelop panel layout designs that control convergence and stress and to monitor groundresponse during operations to verify designs and provide warning of impending stabilityproblems. For detecting both localized roof stability problems and global overburden col-lapse mechanisms, the proposes an integrated panel-wide monitoring system which com-bines the capabilities of load rate monitoring of mobile roof supports (MRSs) with deforma-tion measurements using an extensive array of sensors located near the mining face andthroughout the panel. Two monitoring methods for the detection of localized roof stabilityproblems have been evaluated on the basis of mine measurements and numerical model-ing considerations. These are load rate monitoring of the hydraulic cylinders of mobile roofsupport (MRS) and re mote monitoring of roof movements. Analyses of field data in retreatsections show that roof instabilities are influenced by: (1) pillar failure, (2) pillar yielding, (3)mine seismicity (bumps), (4) geologic structures, and (5) panel layout designs and practice.Pillar yielding and unloading can be conveniently monitored by the load rate monitoringdevice, but to detect impending localized roof falls, additional ground deformation meas-urements are needed near the mining face. By increasing the number of deformationmeasurements in the entire panel, additional safeguards can be achieved for detectingoverburden collapse mechanisms while continuously monitoring local roof stability close tothe retreat line.

  8. Human monoclonal antibodies to West Nile virus identify epitopes on the prM protein.

    Science.gov (United States)

    Calvert, Amanda E; Kalantarov, Gavreel F; Chang, Gwong-Jen J; Trakht, Ilya; Blair, Carol D; Roehrig, John T

    2011-02-05

    Hybridoma cell lines (2E8, 8G8 and 5G12) producing fully human monoclonal antibodies (hMAbs) specific for the pre-membrane (prM) protein of West Nile virus (WNV) were prepared using a human fusion partner cell line, MFP-2, and human peripheral blood lymphocytes from a blood donor diagnosed with WNV fever in 2004. Using site-directed mutagenesis of a WNV-like particle (VLP) we identified 4 amino acid residues in the prM protein unique to WNV and important in the binding of these hMAbs to the VLP. Residues V19 and L33 are important epitopes for the binding of all three hMAbs. Mutations at residue, T20 and T24 affected the binding of hMAbs, 8G8 and 5G12 only. These hMAbs did not significantly protect AG129 interferon-deficient mice or Swiss Webster outbred mice from WNV infection.

  9. Operational Use of the Air Quality Monitor on ISS and Potential for Air Quality Monitoring Onboard Submarines

    Science.gov (United States)

    Limero, Thomas; Jones, Jared; Wallace, William; Mudgett, Paul

    2015-01-01

    The air quality monitor (AQM) began operations on the International Space Station (ISS) in March 2013 and was validated for operational use in January 2014. The AQM is a gas chromatograph-differential mobility spectrometer that currently monitors 22 target compounds in the ISS atmosphere. Data are collected twice per week, although data collection can be more frequent in contingency situations. In its second year, the AQM has provided data to decision-makers on several ISS contaminant related issues in both air and water. AQM has been used in strictly air incidents, such as a potential ammonia leak, and to investigate air contaminants affecting the water processing (excess ethanol). In the latter case data from water monitors and AQM were compared to understand the issue with the water processor. Additionally, the AQM has been moved to different ISS modules to determine whether air is sufficiently mixed between modules so that a central LAB module location is representative of the entire ISS atmosphere. Historic data on the ISS atmosphere in different modules from archival samples (ground lab analysis) suggest that the atmosphere is usually homogenous. This presentation will briefly describe the technical aspects of the AQM operations and summarize the validation results. The main focus of the presentation will be to discuss the results from the AQM survey of the ISS modules and to show how the AQM data has contributed to an understanding of environmental issues that have arisen on ISS. Presentation of a potential ammonia leak (indicated by an alarm) in 2015 will illustrate the use and value of the AQM in such situations.

  10. 40 CFR 60.107a - Monitoring of emissions and operations for fuel gas combustion devices.

    Science.gov (United States)

    2010-07-01

    ... this section will be considered inherently low in sulfur content. (i) Pilot gas for heaters and flares... content in the fuel gas stream going to the loading rack flare). (2) The effective date of the exemption... monitoring and recording the concentration of reduced sulfur in flare gas. The owner or operator of...

  11. Operating a Microwave Radiation Detection Monitor. Module 10. Vocational Education Training in Environmental Health Sciences.

    Science.gov (United States)

    Consumer Dynamics Inc., Rockville, MD.

    This module, one of 25 on vocational education training for careers in environmental health occupations, contains self-instructional materials on operating a microwave radiation detection monitor. Following guidelines for students and instructors and an introduction that explains what the student will learn are three lessons: (1) testing the…

  12. MONDO Project: real time ocean monitoring through Lagrangian drifters during offshore drilling operations

    Energy Technology Data Exchange (ETDEWEB)

    Mafra, Tatiana [Eni Oil do Brasil, Rio de Janeiro, RJ (Brazil); Fragoso, Mauricio da Rocha; Santos, Francisco Alves dos; Cruz, Leonardo M. Marques A.; Pellegrini, Julio A.C.; Cerrone, Bruna Nogueira [Prooceano, Rio de Janeiro, RJ (Brazil); Assireu, Arcilan Trevenzoli [Instituto Nacional de Pesquisas Espaciais (INPE), Sao Jose dos Campos, SP (Brazil)

    2008-07-01

    Monitoring the ocean conditions during offshore operations is essential for both operational and environmental aspects. Environmentally, not only to know better the environment where the activity is taking place, but also to be able to provide fast and accurate response in case of accidents. MONDO Project (Monitoring by Ocean Drifters) is a pioneer initiative from ENI Oil do Brasil and PROOCEANO that aimed to monitor currents as a part of a metoceanographic data monitoring project of drilling operations in Brazilian Waters, in Santos Basin throughout September to November 2007, 40 satellite tracked ocean drifters were deployed will be transmitting data up to November 2008. The results of this project can be used to study a wide range of subjects about ocean dynamics. Following the principles of social and environmental responsibility, MONDO Project aims to benefit the local ecosystem in increasing the scientific knowledge of the area to calibrate hydrodynamic models that will lead to more accurate modeling results and, as a consequence, to a better management of contingency plans. Based on these principles, the project will also provide unrestricted access to oceanographic data even after the end of operations. (author)

  13. A Simulation Dashboard to Monitor Cognitive Workload during Dismounted Military Operations

    NARCIS (Netherlands)

    Beurden, M. van; Streefkerk, J.W.; Kamphuis, W.; Jetten, A.; Trijp, S. van; Venrooij, W.; Veldhuijs, G.

    2016-01-01

    The rapid development and adoption of new technologies (i.e. advanced sensor and communication platforms and monitoring devices) changes the way soldiers operate in the field. A concern frequently expressed by soldiers and commanders, is the increasing demand that technology places on the cognitive

  14. 40 CFR 63.9804 - What are my monitoring system installation, operation, and maintenance requirements?

    Science.gov (United States)

    2010-07-01

    ..., oxidation, and galvanic corrosion. (c) For each pressure CPMS that is used to monitor the pressure drop... where it is easily recognized by plant operating personnel. (6) For positive pressure fabric filter... pressure or induced air fabric filters, the bag leak detector must be installed downstream of the...

  15. 40 CFR 63.7188 - What are my monitoring installation, operation, and maintenance requirements?

    Science.gov (United States)

    2010-07-01

    ... Semiconductor Manufacturing Compliance Requirements § 63.7188 What are my monitoring installation, operation... emissions of your semiconductor process vent through a closed vent system to a control device, you must... evaluation procedure in § 63.7187(i) to demonstrate compliance, you must use the information from the...

  16. Visual evoked potentials monitoring in a case of transient post-operative visual loss

    Directory of Open Access Journals (Sweden)

    Marie Capon

    2016-01-01

    Full Text Available Post-operative visual loss (POVL is a rare, albeit potentially serious complication of general anaesthesia. This report describes the case of a 54-year-old woman who developed transient POVL after general anaesthesia following a left posterior parietal meningioma surgery in the prone position and discusses the usefulness of visual evoked potentials monitoring in such situations.

  17. Operational Monitoring of GOME-2 and IASI Level 1 Product Processing at EUMETSAT

    Science.gov (United States)

    Livschitz, Yakov; Munro, Rosemary; Lang, Rüdiger; Fiedler, Lars; Dyer, Richard; Eisinger, Michael

    2010-05-01

    The growing complexity of operational level 1 radiance products from Low Earth Orbiting (LEO) platforms like EUMETSATs Metop series makes near-real-time monitoring of product quality a challenging task. The main challenge is to provide a monitoring system which is flexible and robust enough to identify and to react to anomalies which may be previously unknown to the system, as well as to provide all means and parameters necessary in order to support efficient ad-hoc analysis of the incident. The operational monitoring system developed at EUMETSAT for monitoring of GOME-2 and IASI level 1 data allows to perform near-real-time monitoring of operational products and instrument's health in a robust and flexible fashion. For effective information management, the system is based on a relational database (Oracle). An Extract, Transform, Load (ETL) process transforms products in EUMETSAT Polar System (EPS) format into relational data structures. The identification of commonalities between products and instruments allows for a database structure design in such a way that different data can be analyzed using the same business intelligence functionality. An interactive analysis software implementing modern data mining techniques is also provided for a detailed look into the data. The system is effectively used for day-to-day monitoring, long-term reporting, instrument's degradation analysis as well as for ad-hoc queries in case of an unexpected instrument or processing behaviour. Having data from different sources on a single instrument and even from different instruments, platforms or numerical weather prediction within the same database allows effective cross-comparison and looking for correlated parameters. Automatic alarms raised by checking for deviation of certain parameters, for data losses and other events significantly reduce time, necessary to monitor the processing on a day-to-day basis.

  18. Monitoring historical masonry structures with operational modal analysis: Two case studies

    Science.gov (United States)

    Ramos, L. F.; Marques, L.; Lourenço, P. B.; De Roeck, G.; Campos-Costa, A.; Roque, J.

    2010-07-01

    The paper addresses two complex case studies of modal and structural identification of monuments in Portugal: the Clock Tower of Mogadouro and the Church of Jerónimos Monastery, in Lisbon. These are being monitored by University of Minho with vibration, temperature and relative air humidity sensors. Operational modal analysis is being used to estimate the modal parameters, followed by statistical analysis to evaluate the environmental effects on the dynamic response. The aim is to explore damage assessment in masonry structures at an early stage by vibration signatures, as a part of a health monitoring process that helps in the preservation of historical constructions. The paper presents the necessary preliminary dynamic analysis steps before the monitoring task, which includes installation of the monitoring system, system identification and subsequent FE model updating analysis, automatic modal identification and investigation of the influence of the environment on the identified modal parameters.

  19. A review of market monitoring activities at U.S. independent system operators

    Energy Technology Data Exchange (ETDEWEB)

    Lesieutre, Bernard C.; Goldman, Charles; Bartholomew, Emily

    2004-01-01

    Policymakers have increasingly recognized the structural impediments to effective competition in electricity markets, which has resulted in a renewed emphasis on the need for careful market design and market monitoring in wholesale and retail electricity markets. In this study, we review the market monitoring activities of four Independent System Operators in the United States, focusing on such topics as the organization of an independent market monitoring unit (MMU), the role and value of external market monitors, performance metrics and indices to aid in market analysis, issues associated with access to confidential market data, and market mitigation and investigation authority. There is consensus across the four ISOs that market monitoring must be organizationally independent from market participants and that ISOs should have authority to apply some degree of corrective actions on the market, though scope and implementation differ across the ISOs. Likewise, current practices regarding access to confidential market data by state energy regulators varies somewhat by ISO. Drawing on our interviews and research, we present five examples that illustrate the impact and potential contribution of ISO market monitoring activities to enhance functioning of wholesale electricity markets. We also discuss several key policy and implementation issues that Western state policymakers and regulators should consider as market monitoring activities evolve in the West.

  20. Research of Zlin Z42 engine´s operation by EDM-800 monitoring system

    Directory of Open Access Journals (Sweden)

    Maria MRAZOVA

    2015-09-01

    Full Text Available The purpose of this paper is based on the analysis of the M137 engine performance by the EDM- 800 monitoring system that is also mounted on Zlin Z42 aircraft in operation of Air Training and Education Centre of the University of Zilina. This research consists of measurements based on the comparison and analysis of the engine parameters where its performance was simulated under various temperature conditions. Measured parameters are monitored during these flight regimes – take off, climb, cruise and approach. Briefly, these measurements are able to detect the existing problems during the engine operation and consequently they will be helpful to prevent potential engine malfunctions in the future operations.

  1. Integrating SAR with Optical and Thermal Remote Sensing for Operational Near Real-Time Volcano Monitoring

    Science.gov (United States)

    Meyer, F. J.; Webley, P.; Dehn, J.; Arko, S. A.; McAlpin, D. B.

    2013-12-01

    Volcanic eruptions are among the most significant hazards to human society, capable of triggering natural disasters on regional to global scales. In the last decade, remote sensing techniques have become established in operational forecasting, monitoring, and managing of volcanic hazards. Monitoring organizations, like the Alaska Volcano Observatory (AVO), are nowadays heavily relying on remote sensing data from a variety of optical and thermal sensors to provide time-critical hazard information. Despite the high utilization of these remote sensing data to detect and monitor volcanic eruptions, the presence of clouds and a dependence on solar illumination often limit their impact on decision making processes. Synthetic Aperture Radar (SAR) systems are widely believed to be superior to optical sensors in operational monitoring situations, due to the weather and illumination independence of their observations and the sensitivity of SAR to surface changes and deformation. Despite these benefits, the contributions of SAR to operational volcano monitoring have been limited in the past due to (1) high SAR data costs, (2) traditionally long data processing times, and (3) the low temporal sampling frequencies inherent to most SAR systems. In this study, we present improved data access, data processing, and data integration techniques that mitigate some of the above mentioned limitations and allow, for the first time, a meaningful integration of SAR into operational volcano monitoring systems. We will introduce a new database interface that was developed in cooperation with the Alaska Satellite Facility (ASF) and allows for rapid and seamless data access to all of ASF's SAR data holdings. We will also present processing techniques that improve the temporal frequency with which hazard-related products can be produced. These techniques take advantage of modern signal processing technology as well as new radiometric normalization schemes, both enabling the combination of

  2. Online Condition Monitoring to Enable Extended Operation of Nuclear Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    Meyer, Ryan M.; Bond, Leonard J.; Ramuhalli, Pradeep

    2012-03-31

    Safe, secure, and economic operation of nuclear power plants will remain of strategic significance. New and improved monitoring will likely have increased significance in the post-Fukushima world. Prior to Fukushima, many activities were already underway globally to facilitate operation of nuclear power plants beyond their initial licensing periods. Decisions to shut down a nuclear power plant are mostly driven by economic considerations. Online condition monitoring is a means to improve both the safety and economics of extending the operating lifetimes of nuclear power plants, enabling adoption of proactive aging management. With regard to active components (e.g., pumps, valves, motors, etc.), significant experience in other industries has been leveraged to build the science base to support adoption for online condition-based maintenance and proactive aging management in the nuclear industry. Many of the research needs are associated with enabling proactive management of aging in passive components (e.g., pipes, vessels, cables, containment structures, etc.). This paper provides an overview of online condition monitoring for the nuclear power industry with an emphasis on passive components. Following the overview, several technology/knowledge gaps are identified, which require addressing to facilitate widespread online condition monitoring of passive components.

  3. Digital monitoring and health diagnosis for mechanical equipment operation safety based on fiber Bragg grating sensor

    Institute of Scientific and Technical Information of China (English)

    Zude ZHOU; Desheng JIANG; Quan LIU

    2009-01-01

    This paper introduces fiber Bragg grating (FBG) based on a fiber optic grating sensor developed to be embedded on mechanical equipment for digital monitoring and health diagnosis. The theoretical and experimental researches on the new-style FBG sensor (FBGS) technology, high-speed demodulation, and data transmission are discussed. The transmission characteristics between the FBG and the detection interface, modeling and compensation method for online distributed multi-parameter digital monitoring and methods for data processing, synchronous sampling, and long-term dynamic digital monitoring using embedded technology are also presented. The acquired information by an FBGS can be used for the optimization of maintenance schedules and refinement of mechanical equipment design. It is a chal-lenge to gather real-time data from components working at high speed and in a severe environment of high temperature, high pressure, and high rotation speed. Currently, there are no sensors or technologies available for digital monitoring and health diagnosis under this rigorous situation for use in mechanical engineering operation safety. As a result, this paper introduces an online distributed and integrated digital monitoring system and health diagnosis. The new principle and new method will contribute to modem measurements in science and technology, mechanical engineering, and large mechanical equipment operation safety.

  4. Pre-operational monitor system of large inland lake water quality with MODIS imagery

    Science.gov (United States)

    Xiaoyu, Zhang; Dingtian, Yang; Xiaofeng, Zhang; Difeng, Wang; Shujing, Li; Delu, Pan

    2005-10-01

    EOS\\MODIS data have been proved a suitable and relative low-cost complementary tool to monitor large inland lake water quality for its re-visit frequency, moderate spatial and spectral resolution and appropriate channels designed for inversing water quality parameters. In this study, by the support of hi-tech research and development program of China, Lake water quality remote monitoring pre-operational system (LWQRMPS) was constructed aimed for practical monitoring of Taihu Lake water quality. The main water quality parameters including Chl-a and SPM, TN and TP inversion algorithm were developed. These parameters were obtained every month from time series fusion satellite data. With the routine trophic state evaluation system, the water quality was assessed every month based on the above retrieved MODIS water quality parameters, varied level of eutrophic area was computed. The obvious high reflectance in near-infrared spectrum caused by blue-green algal bloom support the application of 250m MODIS data in the algal bloom emergency monitor. Therefore, MODIS data were utilized successfully for inversing water quality parameters, evaluating eutrophication status, and detecting algal bloom in near real time. Standard thematic maps were produced and distributed to corresponding management departments. The accuracy of products and retrieve algorithm for operational use were tested with separate data sets. The result suggested that system is good enough for practical monitoring water quality of large size lakes and acquired identification.

  5. Lessons learned from the introduction of autonomous monitoring to the EUVE science operations center

    Science.gov (United States)

    Lewis, M.; Girouard, F.; Kronberg, F.; Ringrose, P.; Abedini, A.; Biroscak, D.; Morgan, T.; Malina, R. F.

    1995-01-01

    The University of California at Berkeley's (UCB) Center for Extreme Ultraviolet Astrophysics (CEA), in conjunction with NASA's Ames Research Center (ARC), has implemented an autonomous monitoring system in the Extreme Ultraviolet Explorer (EUVE) science operations center (ESOC). The implementation was driven by a need to reduce operations costs and has allowed the ESOC to move from continuous, three-shift, human-tended monitoring of the science payload to a one-shift operation in which the off shifts are monitored by an autonomous anomaly detection system. This system includes Eworks, an artificial intelligence (AI) payload telemetry monitoring package based on RTworks, and Epage, an automatic paging system to notify ESOC personnel of detected anomalies. In this age of shrinking NASA budgets, the lessons learned on the EUVE project are useful to other NASA missions looking for ways to reduce their operations budgets. The process of knowledge capture, from the payload controllers for implementation in an expert system, is directly applicable to any mission considering a transition to autonomous monitoring in their control center. The collaboration with ARC demonstrates how a project with limited programming resources can expand the breadth of its goals without incurring the high cost of hiring additional, dedicated programmers. This dispersal of expertise across NASA centers allows future missions to easily access experts for collaborative efforts of their own. Even the criterion used to choose an expert system has widespread impacts on the implementation, including the completion time and the final cost. In this paper we discuss, from inception to completion, the areas where our experiences in moving from three shifts to one shift may offer insights for other NASA missions.

  6. Monitoring of peri-operative fluid administration by individualized goal-directed therapy

    DEFF Research Database (Denmark)

    Bundgaard-Nielsen, M; Holte, Kathrine; Secher, N H;

    2007-01-01

    (n = 725) found a reduced hospital stay. Post-operative nausea and vomiting (PONV) and ileus were reduced in three studies and complications were reduced in four studies. Of the monitors that may be applied for goal-directed therapy, only oesophageal Doppler has been tested adequately; however......, several other options exist. CONCLUSION: Goal-directed therapy with the maximization of flow-related haemodynamic variables reduces hospital stay, PONV and complications, and facilitates faster gastrointestinal functional recovery. So far, oesophageal Doppler is recommended, but other monitors...

  7. First Operating Experiences of Beam Position Monitors in the TESLA Test Facility Linac

    Science.gov (United States)

    Lorenz, R.; Sachwitz, M.; Schreiber, H. J.; Tonisch, F.; Castellano, M.; Patteri, P.; Tazzioli, F.; Catani, L.

    1997-05-01

    Different types of monitors where installed in the TESLA Test Facility Linac to measure the beam position. At each superconducting quadrupole, the transverse beam position will be measured with a resolution of better than 10 μm, using a cylindrical cavity excited in the TM_110-mode by an off-center beam. In addition, two 'warm' cavities working at room temperature were built for the Injector I and the Bunch Compressor. The amplitude of the TM_110-mode and its phase are measured in a homodyne receiver. For the experimental area, stripline monitors having a resolution of better than 100 μm were built, tested and installed. The averaged position of the whole bunch train of Injector I is measured in a narrowband receiver using the amplitude-to-phase conversion. This paper summarizes the designs, cold tests and first operating experiences of both monitor types.

  8. Panel Resource Management (PRM) Implementation and Effects within Safety Review Panel Settings and Dynamics

    Science.gov (United States)

    Taylor, Robert W.; Nash, Sally K.

    2007-01-01

    While technical training and advanced degree's assure proficiency at specific tasks within engineering disciplines, they fail to address the potential for communication breakdown and decision making errors familiar to multicultural environments where language barriers, intimidating personalities and interdisciplinary misconceptions exist. In an effort to minimize these pitfalls to effective panel review, NASA's lead safety engineers to the ISS Safety Review Panel (SRP), and Payload Safety Review Panel (PSRP) initiated training with their engineers, in conjunction with the panel chairs, and began a Panel Resource Management (PRM) program. The intent of this program focuses on the ability to reduce the barriers inhibiting effective participation from all panel attendees by bolstering participants confidence levels through increased communication skills, situational awareness, debriefing, and a better technical understanding of requirements and systems.

  9. 杜比PRM-4200正式在大中华地区上市

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    杜比实验室2012年3月15日在北京宣布杜比PRM-4200专业视频效果测试校正仪现已在大中华地区上市。杜比实验室大中华区高级市场总监郭昌宏,杜比实验室制作及后期制作方案总监Bill Admans及杜比实验室大中华区电影及蓝光业务高级市场经理柯永德到会祝贺并致词,

  10. PRM Field Device Managment%PRM现场设备管理

    Institute of Scientific and Technical Information of China (English)

    王燕

    2005-01-01

    PRM(Plant Resource Manager)是用以提高现场设备管理及维护效率的现场设备管理软件包.PRM的特点是包括了现场设备的预测管理维护,通过对设备维护信息的分类和管理来实现信息维护方法的多样性.此外,还可以通过远程总线方便地获得现场设备的在线操作信息并将这些信息用于维护工作.主要介绍了PRM的功能,以及PRM在降低维护成本方面的突出作用.

  11. Launch Complex 39A, SWMU 008, Operations, Maintenance, and Monitoring Report, Kennedy Space Center, FL

    Science.gov (United States)

    Wilson, Deborah M.

    2016-01-01

    This Operations, Maintenance, and Monitoring Report (OMMR) presents the findings, observations, and results from Year 1 operation of the air sparging (AS) groundwater interim measure (IM) for High-Concentration Plumes (HCPs) and Low-Concentration Plumes (LCPs) within the perimeter fence line at Launch Complex 39A (LC39A) located at Kennedy Space Center (KSC), Florida. The objective of the LC39A groundwater IM is to actively decrease concentrations of trichloroethene (TCE), cis-1,2-dichloroethene (cDCE), and vinyl chloride (VC) in groundwater in the HCP and LCP within the pad perimeter fence line via AS to levels less than Florida Department of Environmental Protection (FDEP) Groundwater Cleanup Target Levels (GCTLs). The objective was developed because LC39A is currently being leased to Space Exploration Technologies (SpaceX), and the original IM for monitored natural attenuation (MNA) over an extended period of time was not suitable for future planned site use.

  12. 3rd International Conference on Condition Monitoring of Machinery in Non-Stationary Operations

    CERN Document Server

    Rubini, Riccardo; D'Elia, Gianluca; Cocconcelli, Marco; Chaari, Fakher; Zimroz, Radoslaw; Bartelmus, Walter; Haddar, Mohamed

    2014-01-01

    This book presents the processings of the third edition of the Condition Monitoring of Machinery in Non-Stationary Operations (CMMNO13) which was held in Ferrara, Italy. This yearly event merges an international community of researchers who met – in 2011 in Wroclaw (Poland) and in 2012 in Hammamet (Tunisia) – to discuss issues of diagnostics of rotating machines operating in complex motion and/or load conditions. The growing interest of the industrial world on the topics covered by the CMMNO13 involves the fields of packaging, automotive, agricultural, mining, processing and wind machines in addition to that of the systems for data acquisition.The participation of speakers and visitors from industry makes the event an opportunity for immediate assessment of the potential applications of advanced methodologies for the signal analysis. Signals acquired from machines often contain contributions from several different components as well as noise. Therefore, the major challenge of condition monitoring is to po...

  13. Collaboration pathway(s) using new tools for optimizing operational climate monitoring from space

    Science.gov (United States)

    Helmuth, Douglas B.; Selva, Daniel; Dwyer, Morgan M.

    2014-10-01

    Consistently collecting the earth's climate signatures remains a priority for world governments and international scientific organizations. Architecting a solution requires transforming scientific missions into an optimized robust `operational' constellation that addresses the needs of decision makers, scientific investigators and global users for trusted data. The application of new tools offers pathways for global architecture collaboration. Recent (2014) rulebased decision engine modeling runs that targeted optimizing the intended NPOESS architecture, becomes a surrogate for global operational climate monitoring architecture(s). This rule-based systems tools provide valuable insight for Global climate architectures, through the comparison and evaluation of alternatives considered and the exhaustive range of trade space explored. A representative optimization of Global ECV's (essential climate variables) climate monitoring architecture(s) is explored and described in some detail with thoughts on appropriate rule-based valuations. The optimization tools(s) suggest and support global collaboration pathways and hopefully elicit responses from the audience and climate science shareholders.

  14. Mathematical model and algorithm of operation scheduling for monitoring situation in local waters

    Directory of Open Access Journals (Sweden)

    Sokolov Boris

    2017-01-01

    Full Text Available A multiple-model approach to description and investigation of control processes in regional maritime security system is presented. The processes considered in this paper were qualified as control processes of computing operations providing monitoring of the situation adding in the local water area and connected to relocation of different ships classes (further the active mobile objects (AMO. Previously developed concept of active moving object (AMO is used. The models describe operation of AMO automated monitoring and control system (AMCS elements as well as their interaction with objects-in-service that are sources or recipients of information being processed. The unified description of various control processes allows synthesizing simultaneously both technical and functional structures of AMO AMCS. The algorithm for solving the scheduling problem is described in terms of the classical theory of optimal automatic control.

  15. The Research on the Construction of Monitoring and Evaluation System for the Operation of Marine Economy in Liaoning Province

    Institute of Scientific and Technical Information of China (English)

    Qianjin; TAN; Weimin; GOU; Peili; SUN

    2015-01-01

    According to the needs of Liaoning province marine economic operation monitoring and evaluation system for capacity building in this paper,it proposes the concept of marine economy operation monitoring and evaluation system,and introduces the system construction content and its architecture,and discusses the key issues on the monitoring index system,evaluation index system,mechanism construction and system implementation. It will help to improve the Liaoning marine economic statistical informatization level and promote the innovation of marine economy in Liaoning,and expect to provide reference for the system construction of other coastal provinces’ provincial marine economy operation monitoring and evaluation system.

  16. Post operative capnostream monitoring in patients with obstructive sleep apnoea symptoms – Case series

    Directory of Open Access Journals (Sweden)

    Vasanth Rao Kadam

    2016-07-01

    Full Text Available Obstructive sleep apnoea (OSA patients on opioid analgesic have an increased incidence of postoperative respiratory complications; prevention of these may be possible with appropriate post-operative monitoring. We recruited 4 OSA patients who had general anaesthesia for orthopaedic and septoplasty surgery. They required Patient Controlled Analgesia (PCA or oral opioids in the post-operative period, hence continuous Saturation of Oxygen (Spo2, End Tidal Carbon dioxide (EtCo2 monitoring on Capnostream monitor with Integrated Pulmonary Index (IPI was organized in high dependency unit. Overnight data was collected every 30 s which included pulse rate, respiratory rate, EtCo2, Spo2, and IPI. The nursing staff was also asked to document if any intervention was carried out due to altered IPI. For first two patient events occurred during various hours but there were no significant events in early night even though increased opioid use at that time. During the period of desaturation nurse intervention required to increase the O2 flow in the first patient but corrected spontaneously in the second patient. IPI index improved over a period of 2 min in most of the events. The duration of desaturation did not correspond with the IPI in only once, remaining period the clinical symptoms were consistent with fall in O2 saturation. The microstream capnography with IPI may provide complete respiratory status of the patient because of its comprehensive parameters on one screen. Main limitation was duration of monitoring was limited to overnight. Capnostream monitoring with IPI may have a role in patients monitoring with OSA on PCA in the postoperative ward but more trials are necessary.

  17. Method and apparatus for monitoring motor operated valve motor output torque and power at valve seating

    Science.gov (United States)

    Casada, Donald A.

    1996-01-01

    A method and apparatus are provided for monitoring a motor operated valve during the brief period when the valve seats and the torque switch trips to deenergize the valve motor. The method uses voltage measurements on the load side of a deenergizing switch that opens to deenergize the motor to determine, among other things, final motor rotational speed and the decelerating torque at motor deenergization.

  18. Use of intellectual sensor technics for monitoring and search-and-rescue operations

    OpenAIRE

    Гурник, Анатолій Васильович; Валуйський, Станіслав Вікторович

    2013-01-01

    The article studies methods for improving the organization of search and rescue operations involving aviation search and rescue facilities using sensor networks, monitoring-signal sensing and geographic information technologies. When collecting information from remote sensors with a single unmanned aerial vehicle (UAV), it is necessary to search for such a UAV flight path, which will enable to read data from all the sensors minimizing the total distance traveled and fuel consumption of the UA...

  19. Modification and Continue Monitoring of Kartini Reactor Tank Liner for Long Term Safe Operation

    Energy Technology Data Exchange (ETDEWEB)

    Puradwi, I. W.; Nitiswati, S.; Tjiptono, T.; Umar, S.; Nugroho, Tri [BATAN, Yogyakarta (Indonesia)

    2013-07-01

    This paper discusses an experience on modification of bulk shielding facility (BSF) and monitoring of the Kartini reactor tank liner through in-service inspection (ISI) for long term safe operation. The objective of BSF modification is to prevent future water penetration from BSF to both the thermalizing column and space between the aluminium reactor tank liner and the concrete. Modification of BSF needs to be conducted because leakage from the BSF has entered to the area behind the aluminium tank liner and has saturated the concrete that has potential to corrode the steel reinforcement bar, and subsequently pushing the aluminium bottom tank and causing the swelling. The three swelling on the bottom tank have been continued monitoring through ISI regularly since 2001 up to now to observe and measure the three swellings profile. Result of swellings profile measurement indicated that swelling had grown slowly in size and became relatively stable. Careful analysis and assessment of the root causes of the swelling indicated that swelling do not present a threat to future safe operation of the reactor and Kartini reactor is considered to be in good condition. As an outcome of modification and continue monitoring, Kartini Reactor in Yogyakarta has been already obtained extended operation license for the third period from Nuclear Energy Regulatory Agency of Indonesia (BAPETEN) up to 2020.

  20. Haemodynamic monitoring in the peri-operative period: the past, the present and the future.

    Science.gov (United States)

    Watson, X; Cecconi, M

    2017-01-01

    Over recent years there has been an increase in the implementation of goal-directed therapy using minimally invasive haemodynamic monitoring techniques to guide peri-operative care. Since the introduction of the pulmonary artery flotation catheter in the 1980s, various haemodynamic monitors have been developed, each associated with their own benefits and limitations. Goal-directed therapy has been well-established as a standard of care in the peri-operative period and has largely been associated with a reduction in morbidity and mortality. However, evidence over the last few years from major studies has led us to question: what is the future for goal-directed therapy? Care of the peri-operative patient has significantly evolved over the last decade and this needs to be taken into account when assessing the results of these studies. We should therefore not look at the effects of goal-directed therapy in isolation but as part of a progressive care bundle. Additionally, other markers of haemodynamic status have also begun to be further appreciated and these are worthy of further investigation. We feel that the future for haemodynamic monitoring remains promising with new areas of interest continuously emerging, but further research is still required. © 2017 The Association of Anaesthetists of Great Britain and Ireland.

  1. Distributed Monitoring for Prevention of Cascading Failures in Operational Power Grids

    CERN Document Server

    Warnier, Martijn; Koç, Yakup; Pauwels, Eric

    2015-01-01

    Electrical power grids are vulnerable to cascading failures that can lead to large blackouts. Detection and prevention of cascading failures in power grids is impor- tant. Currently, grid operators mainly monitor the state (loading level) of individual components in power grids. The complex architecture of power grids, with many interdependencies, makes it difficult to aggregate data provided by local compo- nents in a timely manner and meaningful way: monitoring the resilience with re- spect to cascading failures of an operational power grid is a challenge. This paper addresses this challenge. The main ideas behind the paper are that (i) a robustness metric based on both the topology and the operative state of the power grid can be used to quantify power grid robustness and (ii) a new proposed a distributed computation method with self-stabilizing properties can be used to achieving near real-time monitoring of the robustness of the power grid. Our con- tributions thus provide insight into the resilience wit...

  2. Supply Warehouse#3, SWMU 088 Operations, Maintenance, and Monitoring Report Kennedy Space Center, Florida

    Science.gov (United States)

    Murphy, Alex

    2016-01-01

    This document presents the findings, observations, and results associated with Operations, Maintenance, and Monitoring (OM&M) activities of Corrective Measures Implementation (CMI) activities conducted at Supply Warehouse #3 (SW3) located at John F. Kennedy Space Center (KSC), Florida from October 8, 2015, to September 12, 2016, and performance monitoring results for semi-annual sampling events conducted in March and September 2016. The primary objective of SW3 CMI is to actively decrease concentrations of trichloroethene (TCE) and vinyl chloride (VC) to less than Florida Department of Environmental Protection (FDEP) Natural Attenuation Default Concentrations (NADCs), and the secondary objective is to reduce TCE, cis-1,2-dichloroethene (cDCE), trans-1,2-dichloroethene (tDCE), 1,1-dichloroethene (11DCE), and VC concentrations to less than FDEP Groundwater Cleanup Target Levels (GCTLs). The SW3 facility has been designated Solid Waste Management Unit (SWMU) 088 under KSC's Resource Conservation and Recovery Act (RCRA) Corrective Action Program. Based on the results to date, the SW3 air sparging (AS) system is operating at or below the performance criteria as presented in the 2008 SW3 Corrective Measures Implementation (CMI) Work Plan and 2009 and 2012 CMI Work Plan Addenda. Since the start of AS system operations on December 19, 2012, through the September 2016 groundwater sampling event, TCE concentrations have decreased to less than the GCTL in all wells within the Active Remediation Zone (ARZ), and VC results remain less than NADC but greater than GCTL. Based on these results, team consensus was reached at the October 2016 KSC Remediation Team (KSCRT) meeting to continue AS system operations and semi-annual performance monitoring of volatile organic compounds in March 2017 at ten monitoring wells at select locations, and in September 2017 at four monitoring wells at select locations to reduce VC concentrations to below GCTL. Additionally, surface water samples

  3. Process control and recovery in the Link Monitor and Control Operator Assistant

    Science.gov (United States)

    Lee, Lorrine; Hill, Randall W., Jr.

    1993-01-01

    This paper describes our approach to providing process control and recovery functions in the Link Monitor and Control Operator Assistant (LMCOA). The focus of the LMCOA is to provide semi-automated monitor and control to support station operations in the Deep Space Network. The LMCOA will be demonstrated with precalibration operations for Very Long Baseline Interferometry on a 70-meter antenna. Precalibration, the task of setting up the equipment to support a communications link with a spacecraft, is a manual, time consuming and error-prone process. One problem with the current system is that it does not provide explicit feedback about the effects of control actions. The LMCOA uses a Temporal Dependency Network (TDN) to represent an end-to-end sequence of operational procedures and a Situation Manager (SM) module to provide process control, diagnosis, and recovery functions. The TDN is a directed network representing precedence, parallelism, precondition, and postcondition constraints. The SM maintains an internal model of the expected and actual states of the subsystems in order to determine if each control action executed successfully and to provide feedback to the user. The LMCOA is implemented on a NeXT workstation using Objective C, Interface Builder and the C Language Integrated Production System.

  4. TEG BASED POWER SYSTEM for OPERATION of HEALTH MONITORING SERVER in INDUSTRIES

    Directory of Open Access Journals (Sweden)

    P.S.Raghavendran

    2014-01-01

    Full Text Available In Hazardous environment industries where the emission of toxic gases and effluents will have an impact on the health of the operators, the recording of health parameters of individual operators is very important. In such situation the health monitoring of operators are being monitored and processed centrally by a server and this can be powered by a system of batteries which can be operated from TEG to ensure reliability and to utilize the exhaust heat energy of industries for better performance. This paper describes the Thermo electric generator with battery that supports medical server. The thermoelectric generator converts heat energy into electrical energy. Mathematical model of thermoelectric generator was developed in MATLAB SIMULINK. This exhibits different voltage and current for various temperature differences. The proposed system uses maximum power point tracking algorithm to obtain the maximum power from the thermoelectric generator. This algorithm is developed in embedded MATLAB controller, which gives the firing angle to the DC-DC Boost converter for various temperature differences. This will increase the efficiency of the system.

  5. Incorporating voltage security into the planning, operation and monitoring of restructured electric energy markets

    Science.gov (United States)

    Nair, Nirmal-Kumar

    As open access market principles are applied to power systems, significant changes are happening in their planning, operation and control. In the emerging marketplace, systems are operating under higher loading conditions as markets focus greater attention to operating costs than stability and security margins. Since operating stability is a basic requirement for any power system, there is need for newer tools to ensure stability and security margins being strictly enforced in the competitive marketplace. This dissertation investigates issues associated with incorporating voltage security into the unbundled operating environment of electricity markets. It includes addressing voltage security in the monitoring, operational and planning horizons of restructured power system. This dissertation presents a new decomposition procedure to estimate voltage security usage by transactions. The procedure follows physical law and uses an index that can be monitored knowing the state of the system. The expression derived is based on composite market coordination models that have both PoolCo and OpCo transactions, in a shared stressed transmission grid. Our procedure is able to equitably distinguish the impacts of individual transactions on voltage stability, at load buses, in a simple and fast manner. This dissertation formulates a new voltage stability constrained optimal power flow (VSCOPF) using a simple voltage security index. In modern planning, composite power system reliability analysis that encompasses both adequacy and security issues is being developed. We have illustrated the applicability of our VSCOPF into composite reliability analysis. This dissertation also delves into the various applications of voltage security index. Increasingly, FACT devices are being used in restructured markets to mitigate a variety of operational problems. Their control effects on voltage security would be demonstrated using our VSCOPF procedure. Further, this dissertation investigates

  6. Operational Reliability Assessment of Compressor Gearboxes with Normalized Lifting Wavelet Entropy from Condition Monitoring Information

    Directory of Open Access Journals (Sweden)

    Xiaoli Zhang

    2015-05-01

    Full Text Available Classical reliability assessment methods have predominantly focused on probability and statistical theories, which are insufficient in assessing the operational reliability of individual mechanical equipment with time-varying characteristics. A new approach to assess machinery operational reliability with normalized lifting wavelet entropy from condition monitoring information is proposed, which is different from classical reliability assessment methods depending on probability and statistics analysis. The machinery vibration signals with time-varying operational characteristics are firstly decomposed and reconstructed by means of a lifting wavelet package transform. The relative energy of every reconstructed signal is computed as an energy percentage of the reconstructed signal in the whole signal energy. Moreover, a normalized lifting wavelet entropy is defined by the relative energy to reveal the machinery operational uncertainty. Finally, operational reliability degree is defined by the quantitative value obtained by the normalized lifting wavelet entropy belonging to the range of [0, 1]. The proposed method is applied in the operational reliability assessment of the gearbox in an oxy-generator compressor to validate the effectiveness.

  7. 40 CFR Appendix K to Part 75 - Quality Assurance and Operating Procedures for Sorbent Trap Monitoring Systems

    Science.gov (United States)

    2010-07-01

    ... Pump. Use a leak-tight, vacuum pump capable of operating within the candidate system's flow range. 5.1... sorbent trap monitoring system typically operates. The gas flow meter shall be equipped with any necessary... system typically operates. You may either follow the procedures in section 10.3.1 of Method 5 in...

  8. A sensor management architecture concept for monitoring emissions from open-air demil operations.

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, Michael M.; Robinson, Jerry D.; Stoddard, Mary Clare; Horn, Brent A.; Lipkin, Joel; Foltz, Greg W.

    2005-09-01

    Sandia National Laboratories, CA proposed a sensor concept to detect emissions from open-burning/open-detonation (OB/OD) events. The system would serve two purposes: (1) Provide data to demilitarization operations about process efficiency, allowing process optimization for cleaner emissions and higher efficiency. (2) Provide data to regulators and neighboring communities about materials dispersing into the environment by OB/OD operations. The proposed sensor system uses instrument control hardware and data visualization software developed at Sandia National Laboratories to link together an array of sensors to monitor emissions from OB/OD events. The suite of sensors would consist of various physical and chemical detectors mounted on stationary or mobile platforms. The individual sensors would be wirelessly linked to one another and controlled through a central command center. Real-time data collection from the sensors, combined with integrated visualization of the data at the command center, would allow for feedback to the sensors to alter operational conditions to adjust for changing needs (i.e., moving plume position, increased spatial resolution, increased sensitivity). This report presents a systems study of the problem of implementing a sensor system for monitoring OB/OD emissions. The goal of this study was to gain a fuller understanding of the political, economic, and technical issues for developing and fielding this technology.

  9. Application-Ready Expedited MODIS Data for Operational Land Surface Monitoring of Vegetation Condition

    Directory of Open Access Journals (Sweden)

    Jesslyn F. Brown

    2015-12-01

    Full Text Available Monitoring systems benefit from high temporal frequency image data collected from the Moderate Resolution Imaging Spectroradiometer (MODIS system. Because of near-daily global coverage, MODIS data are beneficial to applications that require timely information about vegetation condition related to drought, flooding, or fire danger. Rapid satellite data streams in operational applications have clear benefits for monitoring vegetation, especially when information can be delivered as fast as changing surface conditions. An “expedited” processing system called “eMODIS” operated by the U.S. Geological Survey provides rapid MODIS surface reflectance data to operational applications in less than 24 h offering tailored, consistently-processed information products that complement standard MODIS products. We assessed eMODIS quality and consistency by comparing to standard MODIS data. Only land data with known high quality were analyzed in a central U.S. study area. When compared to standard MODIS (MOD/MYD09Q1, the eMODIS Normalized Difference Vegetation Index (NDVI maintained a strong, significant relationship to standard MODIS NDVI, whether from morning (Terra or afternoon (Aqua orbits. The Aqua eMODIS data were more prone to noise than the Terra data, likely due to differences in the internal cloud mask used in MOD/MYD09Q1 or compositing rules. Post-processing temporal smoothing decreased noise in eMODIS data.

  10. Remote Operating Monitoring Of Spatial Stability Magnets On A Kurchatov Source Of Synchrotron Radiation

    CERN Document Server

    Barkovsky, E V; Martynenko, V V; Novikov, V A; Udin, L I

    2004-01-01

    During operation of the accelerator because of a nonuniform warm -up of the ring base and constructions of installation there are angular and linear displacements of bending and focusing magnets of a Big Accelerator Ring (BR) of a Kurchatov Source of Synchrotron Radiation. With the purpose of remote operating monitoring of a spatial position of elements BR was used anglemetrical control and measuring system with digital and analog registration in a real time mode. The results of the first stage of a monitoring BR have shown high informativity of the given instrumental - methodical means. The basic radiants of cyclical thermoelastic alternating strains are detected; the amplitudes of angular and linear displacements of magnets from different internal factors evaluated during operation of the accelerator. Is established, that the maximum radial angular and linear displacements of magnets are watched in 3,5-4 day after switching on of installation and achieve in max 30-35 seconds of an arc or 120-150 microns in ...

  11. Westinghouse Hanford Company operational environmental monitoring annual report, calendar year 1994

    Energy Technology Data Exchange (ETDEWEB)

    Schmidt, J.; Fassett, J.W.; Johnson, A.R.; Johnson, V.G.; Markes, B.M.; McKinney, S.M.; Moss, K.J.; Perkins, C.J.; Richterich, L.R.

    1995-08-01

    This document presents the results of the Westinghouse Hanford Company near-facility operational environmental monitoring for 1994 in the 100, 200/600, and 300/400 Areas of the Hanford Site, in south-central Washington State. Surveillance activities included sampling and analyses of ambient air surface water, groundwater, soil, sediments, and biota. Also, external radiation measurements and radiological surveys were taken at waste disposal sites, radiologically controlled areas, and roads. These activities were conducted to assess and control the effects of nuclear facilities and waste sites on the local environment. In addition, diffuse sources were monitored to determine compliance with Federal, State, and/or local regulations. In general, although effects from nuclear facilities are still seen on the Hanford Site and radiation levels are slightly elevated when compared to offsite locations, the differences are less than in previous years.

  12. Westinghouse Hanford Company operational environmental monitoring annual report - calendar year 1995

    Energy Technology Data Exchange (ETDEWEB)

    Schmidt, J.W., Westinghouse Hanford

    1996-07-30

    This document summarizes the results of the Westinghouse Hanford Company (WHC) near-facility operational environmental monitoring for 1995 in the 100, 200/600, and 300/400 Areas of the Hanford Site, in south-central Washington State. Surveillance activities included sampling and analyses of ambient air, surface water,groundwater, soil, sediments, and biota. Also, external radiation measurements and radiological surveys were taken at waste disposal sites, radiologically controlled areas, and roads. These activities were conducted to assess and control the effects of nuclear facilities and waste sites on the local environment. In addition, diffuse sources were monitored to determine compliance with Federal, State, and/or local regulations. In general, although effects from nuclear facilities can still be observed on the Hanford Site and radiation levels are slightly elevated when compared to offsite locations, the differences are less than in previous years.

  13. Interaction design challenges and solutions for ALMA operations monitoring and control

    Science.gov (United States)

    Pietriga, Emmanuel; Cubaud, Pierre; Schwarz, Joseph; Primet, Romain; Schilling, Marcus; Barkats, Denis; Barrios, Emilio; Vila Vilaro, Baltasar

    2012-09-01

    The ALMA radio-telescope, currently under construction in northern Chile, is a very advanced instrument that presents numerous challenges. From a software perspective, one critical issue is the design of graphical user interfaces for operations monitoring and control that scale to the complexity of the system and to the massive amounts of data users are faced with. Early experience operating the telescope with only a few antennas has shown that conventional user interface technologies are not adequate in this context. They consume too much screen real-estate, require many unnecessary interactions to access relevant information, and fail to provide operators and astronomers with a clear mental map of the instrument. They increase extraneous cognitive load, impeding tasks that call for quick diagnosis and action. To address this challenge, the ALMA software division adopted a user-centered design approach. For the last two years, astronomers, operators, software engineers and human-computer interaction researchers have been involved in participatory design workshops, with the aim of designing better user interfaces based on state-of-the-art visualization techniques. This paper describes the process that led to the development of those interface components and to a proposal for the science and operations console setup: brainstorming sessions, rapid prototyping, joint implementation work involving software engineers and human-computer interaction researchers, feedback collection from a broader range of users, further iterations and testing.

  14. Radiation monitoring data of the HTTR rise-to-power test. Results up to 30 MW operation on the rated operation mode

    Energy Technology Data Exchange (ETDEWEB)

    Ashikagaya, Yoshinobu; Yoshino, Toshiaki; Yasu, Katsuji; Sawa, Kazuhiro [Japan Atomic Energy Research Inst., Oarai, Ibaraki (Japan). Oarai Research Establishment; Kurosawa, Yoshiaki [Japan Atomic Energy Research Inst., Takasaki, Gunma (Japan). Takasaki Radiation Chemistry Research Establishment

    2002-12-01

    The High Temperature Engineering Test Reactor (HTTR) have completed the Rise-to-Power test of 9 MW (the single and parallel loaded operation) in the rated operation mode, the rated operation mode and the high-temperature test operation mode with a thermal output of 20 MW (the single and parallel loaded operation). After that the Rise-to-Power test in the rated operation mode (the reactor outlet coolant temperature of 850degC) with a thermal output of 30 MW (the single and parallel loaded operation) were performed between October 20, 2001 and March 11, 2002. This report describes the radiation monitoring data carried out during the HTTR Rise-to-Power test in the rated operation mode with a thermal output of 30 MW. The dose equivalent rate the radioactive air concentration in the working place where the radiation workers enter during the reactor operation were respectively the back ground level and the lower detection limit. There were no release of the radioactive gaseous effluents to the environment through the stack. These radiation monitoring showed clearly the radiation level were very low. This report also describes the part of radiation monitoring data in the HTTR first cycle operation carried out during July 6, 2002 from March 20, 2002. (author)

  15. Radiation monitoring data of the HTTR rise-to-power test. Results up to 30 MW operation on the rated operation mode

    Energy Technology Data Exchange (ETDEWEB)

    Ashikagaya, Yoshinobu; Yoshino, Toshiaki; Yasu, Katsuji; Sawa, Kazuhiro [Japan Atomic Energy Research Inst., Oarai, Ibaraki (Japan). Oarai Research Establishment; Kurosawa, Yoshiaki [Japan Atomic Energy Research Inst., Takasaki, Gunma (Japan). Takasaki Radiation Chemistry Research Establishment

    2002-12-01

    The High Temperature Engineering Test Reactor (HTTR) have completed the Rise-to-Power test of 9 MW (the single and parallel loaded operation) in the rated operation mode, the rated operation mode and the high-temperature test operation mode with a thermal output of 20 MW (the single and parallel loaded operation). After that the Rise-to-Power test in the rated operation mode (the reactor outlet coolant temperature of 850degC) with a thermal output of 30 MW (the single and parallel loaded operation) were performed between October 20, 2001 and March 11, 2002. This report describes the radiation monitoring data carried out during the HTTR Rise-to-Power test in the rated operation mode with a thermal output of 30 MW. The dose equivalent rate the radioactive air concentration in the working place where the radiation workers enter during the reactor operation were respectively the back ground level and the lower detection limit. There were no release of the radioactive gaseous effluents to the environment through the stack. These radiation monitoring showed clearly the radiation level were very low. This report also describes the part of radiation monitoring data in the HTTR first cycle operation carried out during July 6, 2002 from March 20, 2002. (author)

  16. Exogenous Expression of Human Protamine 1 (hPrm1 Remodels Fibroblast Nuclei into Spermatid-like Structures

    Directory of Open Access Journals (Sweden)

    Domenico Iuso

    2015-12-01

    Full Text Available Protamines confer a compact structure to the genome of male gametes. Here, we find that somatic cells can be remodeled by transient expression of protamine 1 (Prm1. Ectopically expressed Prm1 forms scattered foci in the nuclei of fibroblasts, which coalescence into spermatid-like structures, concomitant with a loss of histones and a reprogramming barrier, H3 lysine 9 methylation. Protaminized nuclei injected into enucleated oocytes efficiently underwent protamine to maternal histone TH2B exchange and developed into normal blastocyst stage embryos in vitro. Altogether, our findings present a model to study male-specific chromatin remodeling, which can be exploited for the improvement of somatic cell nuclear transfer.

  17. An integrated approach to monitoring the calibration stability of operational dual-polarization radars

    Science.gov (United States)

    Vaccarono, Mattia; Bechini, Renzo; Chandrasekar, Chandra V.; Cremonini, Roberto; Cassardo, Claudio

    2016-11-01

    The stability of weather radar calibration is a mandatory aspect for quantitative applications, such as rainfall estimation, short-term weather prediction and initialization of numerical atmospheric and hydrological models. Over the years, calibration monitoring techniques based on external sources have been developed, specifically calibration using the Sun and calibration based on ground clutter returns. In this paper, these two techniques are integrated and complemented with a self-consistency procedure and an intercalibration technique. The aim of the integrated approach is to implement a robust method for online monitoring, able to detect significant changes in the radar calibration. The physical consistency of polarimetric radar observables is exploited using the self-consistency approach, based on the expected correspondence between dual-polarization power and phase measurements in rain. This technique allows a reference absolute value to be provided for the radar calibration, from which eventual deviations may be detected using the other procedures. In particular, the ground clutter calibration is implemented on both polarization channels (horizontal and vertical) for each radar scan, allowing the polarimetric variables to be monitored and hardware failures to promptly be recognized. The Sun calibration allows monitoring the calibration and sensitivity of the radar receiver, in addition to the antenna pointing accuracy. It is applied using observations collected during the standard operational scans but requires long integration times (several days) in order to accumulate a sufficient amount of useful data. Finally, an intercalibration technique is developed and performed to compare colocated measurements collected in rain by two radars in overlapping regions. The integrated approach is performed on the C-band weather radar network in northwestern Italy, during July-October 2014. The set of methods considered appears suitable to establish an online tool to

  18. Monitoring of IOR/EOR operations by electrical prospecting; Denki tansaho ni yoru IOR/EOR monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Ushijima, K.; Mizunaga, H.; Ikeda, H.; Masuda, K. [Kyushu University, Fukuoka (Japan). Faculty of Engineering

    1996-10-01

    Fluid flow tomography (FFT) was developed to monitor enhanced oil recovery IOR/EOR operations. This method uses a casing pipe as linear current source by connecting a current electrode with a well inlet, and the other electrode is grounded at a point far different from the well. Potentials are rapidly measured at the same time by multi-channel receiving electrodes installed on the ground to obtain time series data composed of charged potential and superimposed spontaneous potential. After separation of both potentials, the charged potential data are processed by the conventional mise-a-la-masse method to extract local anomaly, determine the residual distribution and relative change distribution of time-sliced apparent resistivity, and obtain the 3-D profile of fluid. The spontaneous potential is also processed to obtain the deflection distribution of time-sliced potential at a specific time. Quantitative 3-D interpretation is conducted focusing attention on the generation mechanism of spontaneous potential. Behavior of underground permeated flow is determined as time series animation images to image fluid direction. This method was effective in real fields. 8 refs., 4 figs.

  19. Toggle PRM: Simultaneous mapping of C-free and C-obstacle - A study in 2D -

    KAUST Repository

    Denny, Jory

    2011-09-01

    Motion planning is known to be difficult. Probabilistic planners have made great advances, but still have difficulty for problems that require planning in narrow passages or on surfaces in Cspace. This work proposes Toggle PRM, a new methodology for PRMs that simultaneously maps both free and obstacle space. In this paper, we focus on 2 DOF problems and show that mapping both spaces leads to increased sampling density in narrow passages and to improved overall efficiency as compared to previous sampling based approaches.

  20. Systematic Bioinformatic Approach for Prediction of Linear B-Cell Epitopes on Dengue E and prM Protein.

    Science.gov (United States)

    Nadugala, Mahesha N; Premaratne, Prasad H; Goonasekara, Charitha L

    2016-01-01

    B-cell epitopes on the envelope (E) and premembrane (prM) proteins of dengue virus (DENV) were predicted using bioinformatics tools, BepiPred, Ellipro, and SVMTriP. Predicted epitopes, 32 and 17 for E and prM proteins, respectively, were then characterized for their level of conservations. The epitopes, EP4/E (48-55), epitope number 4 of E protein at amino acids 48-55, EP9/E (165-182), EP11/E (218-233), EP20/E (322-349), EP21/E (326-353), EP23/E (356-365), and EP25/E (380-386), showed a high intraserotype conservancy with very low pan-serotype conservancy, demonstrating a potential target as serotype specific diagnostic markers. EP3 (30-41) located in domain-I and EP26/E (393-409), EP27/E (416-435), EP28/E (417-430) located in the stem region of E protein, and EP8/prM (93-112) from the prM protein have a pan-serotype conservancy higher than 70%. These epitopes indicate a potential use as universal vaccine candidates, subjected to verification of their potential in viral neutralization. EP2/E (16-21), EP5/E (62-123), EP6/E (63-89), EP19/E (310-329), and EP24/E (371-402), which have more than 50% pan-serotype conservancies, were found on E protein regions that are important in host cell attachment. Previous studies further show evidence for some of these epitopes to generate cross-reactive neutralizing antibodies, indicating their importance in antiviral strategies for DENV. This study suggests that bioinformatic approaches are attractive first line of screening for identification of linear B-cell epitopes.

  1. Folding and Dimerization of Tick-Borne Encephalitis Virus Envelope Proteins prM and E in the Endoplasmic Reticulum

    OpenAIRE

    Ivo C. Lorenz; Allison, Steven L.; Heinz, Franz X; Helenius, Ari

    2002-01-01

    Flavivirus envelope proteins are synthesized as part of large polyproteins that are co- and posttranslationally cleaved into their individual chains. To investigate whether the interaction of neighboring proteins within the precursor protein is required to ensure proper maturation of the individual components, we have analyzed the folding of the flavivirus tick-borne encephalitis (TBE) virus envelope glycoproteins prM and E by using a recombinant plasmid expression system and virus-infected c...

  2. Enhanced Operation of Electricity Distribution Grids Through Smart Metering PLC Network Monitoring, Analysis and Grid Conditioning

    Directory of Open Access Journals (Sweden)

    Iker Urrutia

    2013-01-01

    Full Text Available Low Voltage (LV electricity distribution grid operations can be improved through a combination of new smart metering systems’ capabilities based on real time Power Line Communications (PLC and LV grid topology mapping. This paper presents two novel contributions. The first one is a new methodology developed for smart metering PLC network monitoring and analysis. It can be used to obtain relevant information from the grid, thus adding value to existing smart metering deployments and facilitating utility operational activities. A second contribution describes grid conditioning used to obtain LV feeder and phase identification of all connected smart electric meters. Real time availability of such information may help utilities with grid planning, fault location and a more accurate point of supply management.

  3. Software systems for operation, control, and monitoring of the EBEX instrument

    CERN Document Server

    Milligan, Michael; Aubin, François; Baccigalupi, Carlo; Bao, Chaoyun; Borrill, Julian; Cantalupo, Christopher; Chapman, Daniel; Didier, Joy; Dobbs, Matt; Grainger, Will; Hanany, Shaul; Hillbrand, Seth; Hubmayr, Johannes; Jaffe, Andrew; Johnson, Bradley; Kisner, Theodore; Klein, Jeff; Korotkov, Andrei; Leach, Sam; Lee, Adrian; Levinson, Lorne; Limon, Michele; MacDermid, Kevin; Matsumura, Tomotake; Miller, Amber; Pascale, Enzo; Polsgrove, Daniel; Ponthieu, Nicolas; Raach, Kate; Reichborn-Kjennerud, Britt; Sagiv, Ilan; Tran, Huan; Tucker, Gregory S; Vinokurov, Yury; Yadav, Amit; Zaldarriaga, Matias; Zilic, Kyle; Physics, University of Minnesota School of; Astronomy,; USA,; University, Cardiff; Kingdom, United; University, McGill; Montréal,; Canada,; Avanzati, Scuola Internazionale Superiore di Studi; Trieste,; Italy,; Laboratory, Lawrence Berkeley National; USA,; University, Columbia; York, New; USA,; Standards, National Institute of; Technology,; CO, Boulder; USA,; College, Imperial; London,; Kingdom, United; California, University of; Berkeley,; USA,; University, Brown; Providence,; USA,; Science, Weizmann Institute of; Rehovot,; Israel,; Technology, California Institute of; Pasadena,; USA,; Spatiale, Institut d'Astrophysique; Paris-Sud, Universite; Orsay,; France,; Study, Institute for Advanced; Princeton,; USA,

    2010-01-01

    We present the hardware and software systems implementing autonomous operation, distributed real-time monitoring, and control for the EBEX instrument. EBEX is a NASA-funded balloon-borne microwave polarimeter designed for a 14 day Antarctic flight that circumnavigates the pole. To meet its science goals the EBEX instrument autonomously executes several tasks in parallel: it collects attitude data and maintains pointing control in order to adhere to an observing schedule; tunes and operates up to 1920 TES bolometers and 120 SQUID amplifiers controlled by as many as 30 embedded computers; coordinates and dispatches jobs across an onboard computer network to manage this detector readout system; logs over 3~GiB/hour of science and housekeeping data to an onboard disk storage array; responds to a variety of commands and exogenous events; and downlinks multiple heterogeneous data streams representing a selected subset of the total logged data. Most of the systems implementing these functions have been tested during...

  4. The role of reinstating generation operations in recognition memory and reality monitoring

    Directory of Open Access Journals (Sweden)

    Nieznański Marek

    2014-09-01

    Full Text Available The role of encoding/retrieval conditions compatibility was investigated in a reality-monitoring task. An experiment was conducted which showed a positive effect of reinstating distinctive encoding operations at test. That is, generation of a low-frequency (LF word from the same word fragment at study and test significantly enhanced item recognition memory. However, reinstating of relatively more automatic operations of reading or generating a highfrequency (HF word did not influence recognition performance. Moreover, LF words were better recognized than HF words, but memory for source did not depend on the encoding/retrieval match or on the word-frequency. In comparison with reading, generating an item at study significantly enhanced source memory but generating it at test had no effect. The data were analysed using a multinomial modelling approach which allowed ruling out the influence of a response bias on the measurement of memory ability.

  5. High-Density Fiber Optical Sensor and Instrumentation for Gas Turbine Operation Condition Monitoring

    Directory of Open Access Journals (Sweden)

    Hua Xia

    2013-01-01

    Full Text Available Gas turbine operation control is normally based on thermocouple-measured exhaust temperatures. Due to radiation shielding and bulky package, it is difficult to provide high spatial resolution for measuring can-to-can combustion temperature profile at the exhaust duct. This paper has demonstrated that wavelength-division-multiplexing-based fiber Bragg grating sensors could provide high spatial resolution steady and dynamic temperature measurements. A robust sensor package can be designed with either circumferential sensing cable or radial sensing rake for quasi-distributing multiple fiber sensors in the gas turbine environment. The field validations have demonstrated that quasi-distributed fiber sensors have not only demonstrated its temperature measurement accuracy compared to existing thermocouple sensors but also shown its unique dynamic response amplitude and power spectra that could be utilized for gas turbine transient operation condition monitoring and diagnostics.

  6. ATLAS trigger operations: Monitoring with “Xmon” rate prediction system

    CERN Document Server

    Aukerman, Andrew Todd; The ATLAS collaboration

    2017-01-01

    We present the operations and online monitoring with the “Xmon” rate prediction system for the trigger system at the ATLAS Experiment. A two-level trigger system reduces the LHC’s bunch-crossing rate, 40 MHz at design capacity, to an average recording rate of about 1 kHz, while maintaining a high efficiency of selecting events of interest. The Xmon system uses the luminosity value to predict trigger rates that are, in turn, compared with incoming rates. The predictions rely on past runs to parameterize the luminosity dependency of the event rate for a trigger algorithm. Some examples are given to illustrate the performance of the tool during recent operations.

  7. The National Aviation Operational Monitoring Service (NAOMS): A Documentation of the Development of a Survey Methodology

    Science.gov (United States)

    Connors, Mary M.; Mauro, Robert; Statler, Irving C.

    2012-01-01

    The National Aviation Operational Monitoring Service (NAOMS) was a research project under NASA s Aviation Safety Program during the years from 2000 to 2005. The purpose of this project was to develop a methodology for gaining reliable information on changes over time in the rates-of-occurrence of safety-related events as a means of assessing the safety of the national airspace. The approach was a scientifically designed survey of the operators of the aviation system concerning their safety-related experiences. This report presents the results of the methodology developed and a demonstration of the NAOMS concept through a survey of nearly 20,000 randomly selected air-carrier pilots. Results give evidence that the NAOMS methodology can provide a statistically sound basis for evaluating trends of incidents that could compromise safety. The approach and results are summarized in the report and supporting documentation and complete analyses of results are presented in 14 appendices.

  8. On the Value of Structural Health Monitoring Information for the Operation of Wind Parks

    DEFF Research Database (Denmark)

    Thöns, Sebastian; Faber, Michael H.; Val, Dimitri V.

    2017-01-01

    In the present paper, an approach for the quantification of the Value of Structural Health Monitoring (SHM) Information building upon a framework for infrastructure system utility and decision analysis is developed and applied to the operation of wind parks. The quantification of the value of SHM...... facilitates a benefit and risk informed assessment and optimization of SHM strategies and encompasses models for the infrastructure functionality, the structural constituent and system risks and its management as well as the performance of SHM strategies. A wind park system model incorporating the structural...... for the propagation of SHM information and uncertainties from components to the different system levels and vice versa. The decision to extend the service life and the operation of a wind park is investigated without SHM information and by quantifying the value of several SHM strategies....

  9. Combining models of behaviour with operational data to provide enhanced condition monitoring of AGR cores

    Energy Technology Data Exchange (ETDEWEB)

    West, Graeme M., E-mail: graeme.west@strath.ac.uk; Wallace, Christopher J.; McArthur, Stephen D.J.

    2014-06-01

    Highlights: • Combining laboratory model outputs with operational data. • Isolation of single component from noisy data. • Better understanding of the health of graphite cores. • Extended plant operation through leveraging existing data sources. - Abstract: Installation of new monitoring equipment in Nuclear Power Plants (NPPs) is often difficult and expensive and therefore maximizing the information that can be extracted from existing monitoring equipment is highly desirable. This paper describes the process of combining models derived from laboratory experimentation with current operational plant data to infer an underlying measure of health. A demonstration of this process is provided where the fuel channel bore profile, a measure of core health, is inferred from data gathered during the refuelling process of an Advanced Gas-cooled Reactor (AGR) nuclear power plant core. Laboratory simulation was used to generate a model of an interaction between the fuel assembly and the core. This model is used to isolate a single frictional component from a noisy input signal and use this friction component as a measure of health to assess the current condition of the graphite bricks that comprise the core. In addition, the model is used to generate an expected refuelling response (the noisy input signal) for a given set of channel bore diameter measurements for either insertion of new fuel or removal of spent fuel, providing validation of the model. This benefit of this work is that it provides a greater understanding of the health of the graphite core, which is important for continued and extended operation of the AGR plants in the UK.

  10. A conserved region in the prM protein is a critical determinant in the assembly of flavivirus particles.

    Science.gov (United States)

    Yoshii, Kentaro; Igarashi, Manabu; Ichii, Osamu; Yokozawa, Kana; Ito, Kimihito; Kariwa, Hiroaki; Takashima, Ikuo

    2012-01-01

    Flaviviruses are assembled to bud into the lumen of the endoplasmic reticulum (ER) and are secreted through the vesicle transport pathway, but the details of the molecular mechanism of virion assembly remain largely unknown. In this study, a highly conserved region in the prM protein was identified among flaviviruses. In the subviral particle (SP) system of tick-borne encephalitis virus (TBEV) and Japanese encephalitis virus, secretion of SPs was impaired by a mutation in the conserved region in the prM protein. Viral proteins were sparse in the Golgi complex and accumulated in the ER. Ultrastructural analysis revealed that long filamentous structures, rather than spherical SPs, were observed in the lumen of the ER as a result of the mutation. The production of infectious virions derived from infectious cDNA of TBEV was also reduced by mutations in the conserved region. Molecular modelling analysis suggested that the conserved region is important for the association of prM-envelope protein heterodimers in the formation of a spike of immature virion. These results are the first demonstration that the conserved region in the prM protein is a molecular determinant for the flavivirus assembly process.

  11. Strategy for monitoring and ensuring safe operation of Russian gas transportation systems

    Directory of Open Access Journals (Sweden)

    Dudin Sergey

    2017-01-01

    Full Text Available The authors examined the legislative framework of the Russian Federation operating in the field of industrial safety, and described how to obtain a license to operate hazardous production facilities. The paper demonstrates that the importance should be given to the quality and completeness of the background information, as well as the choice of inspection strategy in evaluating the technical condition of the line section of main gas pipelines. As a part of a package of measures to ensure industrial safety and technical reliability of existing gas pipelines it is proposed to carry out conditioning of their line sections. The paper describes general requirements for pipeline inspection, which include: detection efficiency of dangerous damages and major leaks, maximum accuracy of detection of the defect location, continuity of monitoring throughout the entire range of operation modes of the pipeline, cost recovery at the stages of development and operation of control systems, forecasting the state of the pipeline and the effects of accidents. In practice, these parameters have the prevailing significance.

  12. Operation reliability assessment for cutting tools by applying a proportional covariate model to condition monitoring information.

    Science.gov (United States)

    Cai, Gaigai; Chen, Xuefeng; Li, Bing; Chen, Baojia; He, Zhengjia

    2012-09-25

    The reliability of cutting tools is critical to machining precision and production efficiency. The conventional statistic-based reliability assessment method aims at providing a general and overall estimation of reliability for a large population of identical units under given and fixed conditions. However, it has limited effectiveness in depicting the operational characteristics of a cutting tool. To overcome this limitation, this paper proposes an approach to assess the operation reliability of cutting tools. A proportional covariate model is introduced to construct the relationship between operation reliability and condition monitoring information. The wavelet packet transform and an improved distance evaluation technique are used to extract sensitive features from vibration signals, and a covariate function is constructed based on the proportional covariate model. Ultimately, the failure rate function of the cutting tool being assessed is calculated using the baseline covariate function obtained from a small sample of historical data. Experimental results and a comparative study show that the proposed method is effective for assessing the operation reliability of cutting tools.

  13. Wildlife mitigation burn monitoring program at Teck Coal Limited : Fording River Operations

    Energy Technology Data Exchange (ETDEWEB)

    Smyth, C.R. [Summit Environmental Consultants Inc., Calgary, AB (Canada); Caldwell, T.; Sword, G. [Teck Coal Ltd., Fording River Operations, Elkford, BC (Canada)

    2010-07-01

    This articled discussed a monitoring program evaluating the results of prescribed burns with respect to forest cover reduction, forest production, and wildlife utilization. The burn treatments were undertaken to mitigate the effects of ungulate habitat loss resulting from mine expansion and to increase wildlife habitat suitability and provide winter habitat for elk and moose. Pre-burn and post-burn aerial photographs were used to evaluate the effects of the burn treatments. Data on vegetation, wildlife use, and standing crop production were collected from 36 transects located in paired burned and unburned habitats during the course of the monitoring program, which operated from 1998 to 2007. The mitigation burns were generally found to be successful at improving ungulate habitat. Despite variation among treatment areas and years, the standing crop measurements showed that forest production and animal unit months were greater in the burn treatment areas than in the unburned areas. In particular, the increased cover of palatable grasses and forbs enhanced the elk winter range. The burn treatments altered the stand structure and species dominance. Signs of habitat use showed that elk and mule deer preferentially used the burned sites during the monitoring period. 14 refs., 1 fig.

  14. Operations of cleanrooms during a forest fire including protocols and monitoring results

    Science.gov (United States)

    Matheson, Bruce A.; Egges, Joanne; Pirkey, Michael S.; Lobmeyer, Lynette D.

    2012-10-01

    Contamination-sensitive space flight hardware is typically built in cleanroom facilities in order to protect the hardware from particle contamination. Forest wildfires near the facilities greatly increase the number of particles and amount of vapors in the ambient outside air. Reasonable questions arise as to whether typical cleanroom facilities can adequately protect the hardware from these adverse environmental conditions. On Monday September 6, 2010 (Labor Day Holiday), a large wildfire ignited near the Boulder, Colorado Campus of Ball Aerospace. The fire was approximately 6 miles from the Boulder City limits. Smoke levels from the fire stayed very high in Boulder for the majority of the week after the fire began. Cleanroom operations were halted temporarily on contamination sensitive hardware, until particulate and non-volatile residue (NVR) sampling could be performed. Immediate monitoring showed little, if any effect on the cleanroom facilities, so programs were allowed to resume work while monitoring continued for several days and beyond in some cases. Little, if any, effect was ever noticed in the monitoring performed.

  15. Passive seismic data management and processing to monitor heavy oil steaming operations

    Energy Technology Data Exchange (ETDEWEB)

    Bailey, J.R.; Wang, L. [Society of Petroleum Engineers, Richardson, TX (United States)]|[ExxonMobil Upstream Research Co., Houston, TX (United States); Searles, K.H.; Smith, R.J.; Keith, C.M. [Society of Petroleum Engineers, Canadian Section, Calgary, AB (Canada)]|[Imperial Oil Ltd., Burnaby, BC (Canada)

    2008-10-15

    Cyclic steam injection (CSS) is a cost-effective means to produce heavy oil at the Cold Lake field in Alberta, Canada. The primary obstacle to economic production is the high viscosity of the bitumen. However the bitumen viscosity decreases significantly with temperature. Steam is injected at fracturing conditions, resulting in dilation and recompaction which propagates stress and strain fields in the overburden. An important design consideration involves the mechanical loads on wells resulting from this production process. A seismic production monitoring system was developed in 1995 in the Cold Lake field in order to provide early detection of casing failures and possible fracturing of the overburden. The method was shown to detect a high percentage of casing failures in the production monitoring system. This paper discussed the use and application of methods developed for passive seismic data analysis. The Cold Lake passive seismic system (CLPS) has evolved into an integrated process with a daily workflow. Personnel have identified roles and responsibilities. The paper provided a discussion of the development of a web-based platform running on the operator's internal network called PSWeb. The progression of work in microseismic monitoring of fracture stimulation treatments was also discussed along with the development of FIDO, which used graphical event processing methods to facilitate data analysis and interpretation. Further development of these tools is ongoing to improve casing failure detection and to incorporate more information from seismic data to understand the impact of the CSS process on overburden integrity. 15 refs., 12 figs., 1 appendix.

  16. Online total organic carbon (TOC) monitoring for water and wastewater treatment plants processes and operations optimization

    Science.gov (United States)

    Assmann, Céline; Scott, Amanda; Biller, Dondra

    2017-08-01

    Organic measurements, such as biological oxygen demand (BOD) and chemical oxygen demand (COD) were developed decades ago in order to measure organics in water. Today, these time-consuming measurements are still used as parameters to check the water treatment quality; however, the time required to generate a result, ranging from hours to days, does not allow COD or BOD to be useful process control parameters - see (1) Standard Method 5210 B; 5-day BOD Test, 1997, and (2) ASTM D1252; COD Test, 2012. Online organic carbon monitoring allows for effective process control because results are generated every few minutes. Though it does not replace BOD or COD measurements still required for compliance reporting, it allows for smart, data-driven and rapid decision-making to improve process control and optimization or meet compliances. Thanks to the smart interpretation of generated data and the capability to now take real-time actions, municipal drinking water and wastewater treatment facility operators can positively impact their OPEX (operational expenditure) efficiencies and their capabilities to meet regulatory requirements. This paper describes how three municipal wastewater and drinking water plants gained process insights, and determined optimization opportunities thanks to the implementation of online total organic carbon (TOC) monitoring.

  17. 40 CFR 63.3968 - What are the requirements for continuous parameter monitoring system installation, operation, and...

    Science.gov (United States)

    2010-07-01

    .... Monitoring failures that are caused in part by poor maintenance or careless operation are not malfunctions... install a device to monitor pressure drop across the zeolite wheel or rotary carbon bed. The pressure... signal simulations or via relative accuracy testing. (v) Conduct an accuracy audit every quarter and...

  18. 40 CFR Table 6 to Subpart Ppp of... - Process Vents From Continuous Unit Operations-Monitoring, Recordkeeping, and Reporting Requirements

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 11 2010-07-01 2010-07-01 true Process Vents From Continuous Unit Operations-Monitoring, Recordkeeping, and Reporting Requirements 6 Table 6 to Subpart PPP of Part 63... Subpart PPP of Part 63—Process Vents From Continuous Unit Operations—Monitoring, Recordkeeping, and...

  19. [Hardware-software system for monitoring parameters and characteristics of X-ray computer tomographs under operation conditions].

    Science.gov (United States)

    Blinov, N N; Zelikman, M I; Kruchinin, S A

    2007-01-01

    The results of testing of hardware and software for monitoring parameters (mean number of CT units, noise, field uniformity, high-contrast spatial resolution, layer width, dose) and characteristics (modulation transfer function) of X-ray computer tomographs are presented. The developed hardware and software are used to monitor the stability of X-ray computer tomograph parameters under operation conditions.

  20. A human PrM antibody that recognizes a novel cryptic epitope on dengue E glycoprotein.

    Science.gov (United States)

    Chan, Annie Hoi Yi; Tan, Hwee Cheng; Chow, Angelia Yee; Lim, Angeline Pei Chiew; Lok, Shee Mei; Moreland, Nicole J; Vasudevan, Subhash G; MacAry, Paul A; Ooi, Eng Eong; Hanson, Brendon J

    2012-01-01

    Dengue virus (DENV) is a major mosquito-borne pathogen infecting up to 100 million people each year; so far no effective treatment or vaccines are available. Recently, highly cross-reactive and infection-enhancing pre-membrane (prM)-specific antibodies were found to dominate the anti-DENV immune response in humans, raising concern over vaccine candidates that contain native dengue prM sequences. In this study, we have isolated a broadly cross-reactive prM-specific antibody, D29, during a screen with a non-immunized human Fab-phage library against the four serotypes of DENV. The antibody is capable of restoring the infectivity of virtually non-infectious immature DENV (imDENV) in FcγR-bearing K562 cells. Remarkably, D29 also cross-reacted with a cryptic epitope on the envelope (E) protein located to the DI/DII junction as evidenced by site-directed mutagenesis. This cryptic epitope, while inaccessible to antibody binding in a native virus particle, may become exposed if E is not properly folded. These findings suggest that generation of anti-prM antibodies that enhance DENV infection may not be completely avoided even with immunization strategies employing E protein alone or subunits of E proteins.

  1. Improving the Quality of Non-Holonomic Motion by Hybridizing C-PRM Paths

    CERN Document Server

    Berger, Itamar; Zohar, Gal; Raveh, Barak; Halperin, Dan

    2010-01-01

    Sampling-based motion planners are an effective means for generating collision-free motion paths. However, the quality of these motion paths, with respect to different quality measures such as path length, clearance, smoothness or energy, is often notoriously low. This problem is accentuated in the case of non-holonomic sampling-based motion planning, in which the space of feasible motion trajectories is restricted. In this study, we combine the C-PRM algorithm by Song and Amato with our recently introduced path-hybridization approach, for creating high quality non-holonomic motion paths, with combinations of several different quality measures such as path length, smoothness or clearance, as well as the number of reverse car motions. Our implementation includes a variety of code optimizations that result in nearly real-time performance, and which we believe can be extended with further optimizations to a real-time tool for the planning of high-quality car-like motion.

  2. Osteoarthritis. The role of physical and rehabilitation medicine physicians. The European perspective based on the best evidence. A paper by the UEMS-PRM Section Professional Practice Committee.

    Science.gov (United States)

    Ilieva, E M; Oral, A; Küçükdeveci, A A; Varela, E; Valero, R; Berteanu, M; Christodoulou, N

    2013-08-01

    One of the objectives of the Professional Practice Committee (PPC) of the Physical and Rehabilitation Medicine (PRM) Section of the Union of European Medical Specialists (UEMS) is the development of the field of competence of PRM physicians in Europe. To achieve this objective, UEMS PRM Section PPC has adopted a systematic action plan of preparing a series of papers describing the role of PRM physicians in a number of disabling health conditions, based on the evidence of effectiveness of the PRM interventions. Osteoarthritis (OA) is the most common joint disorder and the major cause of musculoskeletal pain and limited mobility in the elderly in the world. Therefore, proper management of persons with OA is of substantial importance. The goal of OA management is to reduce the impact of OA on the individual by reducing pain and improving function, activities and participation. The aim of this paper is to descibe the explicit role of PRM physicians in providing management for persons with OA. The optimal management of OA requires the combination of both non-pharmacological and pharmacological approaches, an issue most of the main guidelines on the evidence-based management of OA share in common. There is good level of evidence about the effectiveness of PRM interventions in the management of OA: high level of evidence about the effect of education, weight reduction and exercise and growing evidence about the effectiveness of physical agent modalities. PRM specialists are involved not only in diagnosis and medical and physical treatments of OA, but, as a rehabilitation strategy, they also deal with the problems of the person focusing on the improvement of all components of human functioning as defined in the ICF including personal and environmental factors with a holistic approach. ICF core sets for OA serve as excellent models for directing proper assessments as well as targeting interventions. PRM specialists well meet the needs of people with OA from the early stages

  3. Capability of C-Band SAR for Operational Wetland Monitoring at High Latitudes

    Directory of Open Access Journals (Sweden)

    Julia Reschke

    2012-10-01

    Full Text Available Wetlands store large amounts of carbon, and depending on their status and type, they release specific amounts of methane gas to the atmosphere. The connection between wetland type and methane emission has been investigated in various studies and utilized in climate change monitoring and modelling. For improved estimation of methane emissions, land surface models require information such as the wetland fraction and its dynamics over large areas. Existing datasets of wetland dynamics present the total amount of wetland (fraction for each model grid cell, but do not discriminate the different wetland types like permanent lakes, periodically inundated areas or peatlands. Wetland types differently influence methane fluxes and thus their contribution to the total wetland fraction should be quantified. Especially wetlands of permafrost regions are expected to have a strong impact on future climate due to soil thawing. In this study ENIVSAT ASAR Wide Swath data was tested for operational monitoring of the distribution of areas with a long-term SW near 1 (hSW in northern Russia (SW = degree of saturation with water, 1 = saturated, which is a specific characteristic of peatlands. For the whole northern Russia, areas with hSW were delineated and discriminated from dynamic and open water bodies for the years 2007 and 2008. The area identified with this method amounts to approximately 300,000 km2 in northern Siberia in 2007. It overlaps with zones of high carbon storage. Comparison with a range of related datasets (static and dynamic showed that hSW represents not only peatlands but also temporary wetlands associated with post-forest fire conditions in permafrost regions. Annual long-term monitoring of change in boreal and tundra environments is possible with the presented approach. Sentinel-1, the successor of ENVISAT ASAR, will provide data that may allow continuous monitoring of these wetland dynamics in the future complementing global observations of

  4. Ozone monitoring in the UK (United Kingdom): A review of 1978/8. Data from monitoring sites operated by Warren Spring Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Bower, J.S.; Broughton, G.F.; Dando, M.T.

    1988-01-01

    A new national air-quality monitoring network has been established for the Department of the Environment. Its purpose is to determine rural baseline concentrations of ozone and other pollutants throughout the United Kingdom. The report describes the background to the establishment of the network, together with its present structure and instrumentation. A series of data analyses are presented and discussed, with the intention of providing a broad and preliminary overview of ozone observations at WSL-operated monitoring sites throughout the first full year of network operation. Average and peak levels of ozone during 1987/8 are quantified, seasonal and diurnal variations are determined, and high pollution periods are examined.

  5. CMEMS (Copernicus Marine Environment Monitoring Service) In Situ Thematic Assembly Centre: A service for operational Oceanography

    Science.gov (United States)

    Manzano Muñoz, Fernando; Pouliquen, Sylvie; Petit de la Villeon, Loic; Carval, Thierry; Loubrieu, Thomas; Wedhe, Henning; Sjur Ringheim, Lid; Hammarklint, Thomas; Tamm, Susanne; De Alfonso, Marta; Perivoliotis, Leonidas; Chalkiopoulos, Antonis; Marinova, Veselka; Tintore, Joaquin; Troupin, Charles

    2016-04-01

    Copernicus, previously known as GMES (Global Monitoring for Environment and Security), is the European Programme for the establishment of a European capacity for Earth Observation and Monitoring. Copernicus aims to provide a sustainable service for Ocean Monitoring and Forecasting validated and commissioned by users. From May 2015, the Copernicus Marine Environment Monitoring Service (CMEMS) is working on an operational mode through a contract with services engagement (result is regular data provision). Within CMEMS, the In Situ Thematic Assembly Centre (INSTAC) distributed service integrates in situ data from different sources for operational oceanography needs. CMEMS INSTAC is collecting and carrying out quality control in a homogeneous manner on data from providers outside Copernicus (national and international networks), to fit the needs of internal and external users. CMEMS INSTAC has been organized in 7 regional Dissemination Units (DUs) to rely on the EuroGOOS ROOSes. Each DU aggregates data and metadata provided by a series of Production Units (PUs) acting as an interface for providers. Homogeneity and standardization are key features to ensure coherent and efficient service. All DUs provide data in the OceanSITES NetCDF format 1.2 (based on NetCDF 3.6), which is CF compliant, relies on SeaDataNet vocabularies and is able to handle profile and time-series measurements. All the products, both near real-time (NRT) and multi-year (REP), are available online for every CMEMS registered user through an FTP service. On top of the FTP service, INSTAC products are available through Oceanotron, an open-source data server dedicated to marine observations dissemination. It provides services such as aggregation on spatio-temporal coordinates and observed parameters, and subsetting on observed parameters and metadata. The accuracy of the data is checked on various levels. Quality control procedures are applied for the validity of the data and correctness tests for the

  6. Operational control of radiation conditions in Space Monitoring Data Center of Moscow State University

    Science.gov (United States)

    Kalegaev, Vladimir; Shugay, Yulia; Bobrovnikov, Sergey; Kuznetsov, Nikolay; Barinova, Vera; Myagkova, Irina; Panasyuk, Mikhail

    2016-07-01

    Space Monitoring Data Center (SMDC) of Moscow State University provides mission support for Russian satellites and give operational analysis of radiation conditions in space. SMDC Web-sites (http://smdc.sinp.msu.ru/ and http://swx.sinp.msu.ru/) give access to current data on the level of solar activity, geomagnetic and radiation state of Earth's magnetosphere and heliosphere in near-real time. For data analysis the models of space environment factors working online have been implemented. Interactive services allow one to retrieve and analyze data at a given time moment. Forecasting applications including solar wind parameters, geomagnetic and radiation condition forecasts have been developed. Radiation dose and SEE rate control are of particular importance in practical satellite operation. Satellites are always under the influence of high-energy particle fluxes during their orbital flight. The three main sources of particle fluxes: the Earth's radiation belts, the galactic cosmic rays, and the solar energetic particles (SEP), are taken into account by SMDC operational services to estimate the radiation dose caused by high-energy particles to a satellite at LEO orbits. ISO 15039 and AP8/AE8 physical models are used to estimate effects of galactic cosmic rays and radiation belt particle fluxes. Data of geosynchronous satellites (GOES or Electro-L1) allow to reconstruct the SEP fluxes spectra at a given low Earth orbit taking into account the geomagnetic cut-off depending on geomagnetic activity level.

  7. Microbial air monitoring in the operating theatres of Salam Center for Cardiac Surgery in Khartoum (Sudan

    Directory of Open Access Journals (Sweden)

    Margherita Scapaticci

    2012-06-01

    Full Text Available The seriousness of postoperative infections and the increased susceptibility of patients undergoing cardiac surgery increase the demand for the operating theatre (OT asepsis to prevent bacterial infections. In fact, the organisms carried by the air reach the wound after having sedimented onto sterile field. The air represents a critical point for quality control of air filtration systems, for sanitization procedures and for the evolution of hygienic features of the OT environment.Aim of the study is to evaluate the prevalence of microorganisms found in the operating rooms (OR air monitoring in the Salam Center for Cardiac Surgery of Khartoum (Sudan between July 2008 and March 2009.The specimens were collected every month in two different times: “OR at rest” (after sanitization and “OR operational”, using sedimentation method (Fisher 1972. Results showed that each sample collected at rest had IMA (index of microbial air contamination < 5CFU/plt, whereas the bacterial growth was between 25 and 50 CFU/plt when the samples had been collected in the same places during operating activities.This indicate the effectiveness of sanitization procedures and confirm that people working in OT are an important source of bacteria causing postoperative infections. Coagulase negative Staphylococci, Gram negative bacillus and Staphylococcus aureus spp. were the predominant organisms isolated.

  8. Collaboration pathway(s) using new tools for optimizing `operational' climate monitoring from space

    Science.gov (United States)

    Helmuth, Douglas B.; Selva, Daniel; Dwyer, Morgan M.

    2015-09-01

    Consistently collecting the earth's climate signatures remains a priority for world governments and international scientific organizations. Architecting a long term solution requires transforming scientific missions into an optimized robust `operational' constellation that addresses the collective needs of policy makers, scientific communities and global academic users for trusted data. The application of new tools offers pathways for global architecture collaboration. Recent rule-based expert system (RBES) optimization modeling of the intended NPOESS architecture becomes a surrogate for global operational climate monitoring architecture(s). These rulebased systems tools provide valuable insight for global climate architectures, by comparison/evaluation of alternatives and the sheer range of trade space explored. Optimization of climate monitoring architecture(s) for a partial list of ECV (essential climate variables) is explored and described in detail with dialogue on appropriate rule-based valuations. These optimization tool(s) suggest global collaboration advantages and elicit responses from the audience and climate science community. This paper will focus on recent research exploring joint requirement implications of the high profile NPOESS architecture and extends the research and tools to optimization for a climate centric case study. This reflects work from SPIE RS Conferences 2013 and 2014, abridged for simplification30, 32. First, the heavily securitized NPOESS architecture; inspired the recent research question - was Complexity (as a cost/risk factor) overlooked when considering the benefits of aggregating different missions into a single platform. Now years later a complete reversal; should agencies considering Disaggregation as the answer. We'll discuss what some academic research suggests. Second, using the GCOS requirements of earth climate observations via ECV (essential climate variables) many collected from space-based sensors; and accepting their

  9. Highly conserved residues in the helical domain of dengue virus type 1 precursor membrane protein are involved in assembly, precursor membrane (prM) protein cleavage, and entry.

    Science.gov (United States)

    Hsieh, Szu-Chia; Wu, Yi-Chieh; Zou, Gang; Nerurkar, Vivek R; Shi, Pei-Yong; Wang, Wei-Kung

    2014-11-28

    The envelope and precursor membrane (prM) proteins of dengue virus (DENV) are present on the surface of immature virions. During maturation, prM protein is cleaved by furin protease into pr peptide and membrane (M) protein. Although previous studies mainly focusing on the pr region have identified several residues important for DENV replication, the functional role of M protein, particularly the α-helical domain (MH), which is predicted to undergo a large conformational change during maturation, remains largely unknown. In this study, we investigated the role of nine highly conserved MH domain residues in the replication cycle of DENV by site-directed mutagenesis in a DENV1 prME expression construct and found that alanine substitutions introduced to four highly conserved residues at the C terminus and one at the N terminus of the MH domain greatly affect the production of both virus-like particles and replicon particles. Eight of the nine alanine mutants affected the entry of replicon particles, which correlated with the impairment in prM cleavage. Moreover, seven mutants were found to have reduced prM-E interaction at low pH, which may inhibit the formation of smooth immature particles and exposure of prM cleavage site during maturation, thus contributing to inefficient prM cleavage. Taken together, these results are the first report showing that highly conserved MH domain residues, located at 20-38 amino acids downstream from the prM cleavage site, can modulate the prM cleavage, maturation of particles, and virus entry. The highly conserved nature of these residues suggests potential targets of antiviral strategy.

  10. Hardware and software system for monitoring oil pump operation in power high-voltage transformers

    Directory of Open Access Journals (Sweden)

    Михайло Дмитрович Дяченко

    2017-07-01

    Full Text Available The article considers the basic prerequisites for the creation of an automated monitoring system for oil pumps of high-voltage transformers. This is due to the fact that the long operation of oil pumps results in deterioration and destruction of bearings, rubbing of the rotor, breakage and damage to the impeller, leakage, etc., which inevitably causes a significant decrease in the insulating properties of the transformer oil and leads to expenditures for its further recovery. False triggerings of gas protection sometimes occur. Continuous operation of the electric motor also requires additional equipment to protect the motor itself from various emergency situations, such as a short in the stator winding, a housing breakdown, an incomplete phase mode, etc. The use of stationary systems provides: diagnosing defects at an early stage of their development, increasing the reliability and longevity of the equipment components, increasing the overhaul period, decreasing the number of emergency stops, and adjusting the schedule of preventative maintenance. The basic principles of identification of the damaged part of the oil pump are given, the hardware and algorithmic solutions are considered in the work. The full-scale tests of the model sample on the power transformer of the high-voltage substation confirmed the assumption of the possibility of detecting the damaged unit separating it from the rest connected in one mechanical structure. A detailed analysis of the operation of each of the units is carried out by means of the general substation switchboard and displayed as graphs, diagrams and text messages. When the limit values of vibration are reached, faults in the operation of the unit are detected, the overlimit current values, a warning alarm is activated, and the command to disconnect the damaged unit is issued. The optimal solution for the organization of the information collection system using the principle of sensor networks, but combined

  11. Operation Safe Haven: an evaluation of health surveillance and monitoring in an acute setting.

    Science.gov (United States)

    Bennett, C; Mein, J; Beers, M; Harvey, B; Vemulpad, S; Chant, K; Dalton, C

    2000-02-17

    From May to June 1999, 3,920 ethnic Albanians from Kosovo arrived in Australia as part of Operation Safe Haven. These people were evacuated from refugee camps in the former Yugoslav Republic of Macedonia. Initial processing in Australia occurred at East Hills Reception Centre, and accommodation for the duration of stay was provided in eight Haven Centres in five States. The arrival of a large number of refugees in a short time frame is unprecedented in Australia. A health surveillance system was developed and critical health data were collected to assess health status and needs, plan care, monitor for potential outbreaks of communicable diseases, track service use, to meet international reporting requirements and document our response to this crisis. In this article the health surveillance system is evaluated and suggestions are offered for the formulation of specific guidelines necessary for health surveillance in acute settings.

  12. Real-time monitoring and operational control of drinking-water systems

    CERN Document Server

    Ocampo-Martínez, Carlos; Pérez, Ramon; Cembrano, Gabriela; Quevedo, Joseba; Escobet, Teresa

    2017-01-01

    This book presents a set of approaches for the real-time monitoring and control of drinking-water networks based on advanced information and communication technologies. It shows the reader how to achieve significant improvements in efficiency in terms of water use, energy consumption, water loss minimization, and water quality guarantees. The methods and approaches presented are illustrated and have been applied using real-life pilot demonstrations based on the drinking-water network in Barcelona, Spain. The proposed approaches and tools cover: • decision-making support for real-time optimal control of water transport networks, explaining how stochastic model predictive control algorithms that take explicit account of uncertainties associated with energy prices and real demand allow the main flow and pressure actuators—pumping stations and pressure regulation valves—and intermediate storage tanks to be operated to meet demand using the most sustainable types of source and with minimum electricity costs;...

  13. Track-monitoring from the dynamic response of an operational train

    Science.gov (United States)

    Lederman, George; Chen, Siheng; Garrett, James; Kovačević, Jelena; Noh, Hae Young; Bielak, Jacobo

    2017-03-01

    We explore a data-driven approach for monitoring rail infrastructure from the dynamic response of a train in revenue-service. Presently, track inspection is performed either visually or with dedicated track geometry cars. In this study, we examine a more economical approach where track inspection is performed by analyzing vibration data collected from an operational passenger train. The high frequency with which passenger trains travel each section of track means that faults can be detected sooner than with dedicated inspection vehicles, and the large number of passes over each section of track makes a data-driven approach statistically feasible. We have deployed a test-system on a light-rail vehicle and have been collecting data for the past two years. The collected data underscores two of the main challenges that arise in train-based track monitoring: the speed of the train at a given location varies from pass to pass and the position of the train is not known precisely. In this study, we explore which feature representations of the data best characterize the state of the tracks despite these sources of uncertainty (i.e., in the spatial domain or frequency domain), and we examine how consistently change detection approaches can identify track changes from the data. We show the accuracy of these different representations, or features, and different change detection approaches on two types of track changes, track replacement and tamping (a maintenance procedure to improve track geometry), and two types of data, simulated data and operational data from our test-system. The sensing, signal processing, and data analysis we propose in the study could facilitate safer trains and more cost-efficient maintenance in the future. Moreover, the proposed approach is quite general and could be extended to other parts of the infrastructure, including bridges.

  14. Statistically Filtering Data for Operational Modal Analysis under Ambient Vibration in Structural Health Monitoring Systems

    Directory of Open Access Journals (Sweden)

    Wang Liang

    2016-01-01

    Full Text Available Operational modal analysis (OMA is prevalent in large structure modal identification for that it asks for output measurements only. To guarantee identification accuracy, theoretically, OMA data need to be a random process of Gaussian white noise (GWN. Although numerous OMA applications are found in practice, few have particularly discussed the data distribution and to what extent it would blur the modal judgement. This paper presents a method to sieve segments mostly obeying the GWN distribution out of a recording. With a windowing technique, the data segments are evaluated by the modified Kurtosis value. The process has been demonstrated on the monitoring data of two case study structures: one is a laboratory truss bridge excited by artificial forces, the other is a real cable-stayed bridge subject to environmental loads. The results show that weak randomness data may result in false peaks that would possibly mislead the non-parametric modal identification, such as using the Frequency Domain Decomposition method. To overcome, cares on selecting the optimal segment shall be exercised. The proposed method is verified effective to find the most suitable data for modal identification of structural health monitoring systems.

  15. Experience of molecular monitoring techniques in upstream oil and gas operations

    Energy Technology Data Exchange (ETDEWEB)

    Mitchell, Anthony F.; Anfindsen, Hilde; Liengen, Turid; Molid, Solfrid [Statoil ASA (Denmark)

    2011-07-01

    For a numbers of years, molecular monitoring tools have been used in upstream oil and gas operations but the results have given only limited added value. This paper discusses the various techniques available for upstream molecular monitoring which provides scope for identification of microbial influenced problems. The methodology, which consists of analyzing solid samples using traditional as well as molecular techniques, is detailed. Two cases were studied with the objective of determining if microbial contamination was contributing to the problem. The first case was a study of amorphous deposits in production wells and mainly iron sulphide was found. The second study was of amorphous deposits in water injection wells and the analysis showed typical components of drilling and completion fluids with some organic material. Two more cases, corrosion of tubing in a water injection well and flow line corrosion, are discussed and the results are given. From the study, it can be concluded that failure can be due to several factors, chemical and biological.

  16. Advances in Remote Sensing of Agriculture: Context Description, Existing Operational Monitoring Systems and Major Information Needs

    Directory of Open Access Journals (Sweden)

    Clement Atzberger

    2013-02-01

    Full Text Available Many remote sensing applications are devoted to the agricultural sector. Representative case studies are presented in the special issue “Advances in Remote Sensing of Agriculture”. To complement the examples published within the special issue, a few main applications with regional to global focus were selected for this review, where remote sensing contributions are traditionally strong. The selected applications are put in the context of the global challenges the agricultural sector is facing: minimizing the environmental impact, while increasing production and productivity. Five different applications have been selected, which are illustrated and described: (1 biomass and yield estimation, (2 vegetation vigor and drought stress monitoring, (3 assessment of crop phenological development, (4 crop acreage estimation and cropland mapping and (5 mapping of disturbances and land use/land cover (LULC changes. Many other applications exist, such as precision agriculture and irrigation management (see other special issues of this journal, but were not included to keep the paper concise. The paper starts with an overview of the main agricultural challenges. This section is followed by a brief overview of existing operational monitoring systems. Finally, in the main part of the paper, the mentioned applications are described and illustrated. The review concludes with some key recommendations.

  17. Integrating UF6 Cylinder RF Tracking With Continuous Load Cell Monitoring for Verifying Declared UF6 Feed and Withdrawal Operations Verifying Declared UF6 Feed and Withdrawal Operations

    Energy Technology Data Exchange (ETDEWEB)

    Krichinsky, Alan M [ORNL; Miller, Paul [ORNL; Pickett, Chris A [ORNL; Richardson, Dave [ORNL; Rowe, Nathan C [ORNL; Whitaker, J Michael [ORNL; Younkin, James R [ORNL

    2009-01-01

    Oak Ridge National Laboratory is demonstrating the integration of UF6 cylinder tracking, using RF technology, with continuous load cell monitoring (CLCM) at mock UF6 feed and withdrawal (F&W) stations. CLCM and cylinder tracking are two of several continuous-monitoring technologies that show promise in providing integrated safeguards of F&W operations at enrichment plants. Integrating different monitoring technologies allows advanced, automated event processing to screen innocuous events thereby minimizing false alerts to independent inspectors. Traditionally, international inspectors rely on batch verification of material inputs and outputs derived from operator declarations and periodic on-site inspections at uranium enrichment plants or other nuclear processing facilities. Continuously monitoring F&W activities between inspections while providing filtered alerts of significant operational events will substantially increase the amount of valuable information available to inspectors thereby promising to enhance the effectiveness of safeguards and to improve efficiency in conducting on-site inspections especially at large plants for ensuring that all operations are declared.

  18. Cloud Cover Assessment for Operational Crop Monitoring Systems in Tropical Areas

    Directory of Open Access Journals (Sweden)

    Isaque Daniel Rocha Eberhardt

    2016-03-01

    Full Text Available The potential of optical remote sensing data to identify, map and monitor croplands is well recognized. However, clouds strongly limit the usefulness of optical imagery for these applications. This paper aims at assessing cloud cover conditions over four states in the tropical and sub-tropical Center-South region of Brazil to guide the development of an appropriate agricultural monitoring system based on Landsat-like imagery. Cloudiness was assessed during overlapping four months periods to match the typical length of crop cycles in the study area. The percentage of clear sky occurrence was computed from the 1 km resolution MODIS Cloud Mask product (MOD35 considering 14 years of data between July 2000 and June 2014. Results showed high seasonality of cloud occurrence within the crop year with strong variations across the study area. The maximum seasonality was observed for the two states in the northern part of the study area (i.e., the ones closer to the Equator line, which also presented the lowest averaged values (15% of clear sky occurrence during the main (summer cropping period (November to February. In these locations, optical data faces severe constraints for mapping summer crops. On the other hand, relatively favorable conditions were found in the southern part of the study region. In the South, clear sky values of around 45% were found and no significant clear sky seasonality was observed. Results underpin the challenges to implement an operational crop monitoring system based solely on optical remote sensing imagery in tropical and sub-tropical regions, in particular if short-cycle crops have to be monitored during the cloudy summer months. To cope with cloudiness issues, we recommend the use of new systems with higher repetition rates such as Sentinel-2. For local studies, Unmanned Aircraft Vehicles (UAVs might be used to augment the observing capability. Multi-sensor approaches combining optical and microwave data can be another

  19. [The possibilities for the transcranial monitoring of the blood flow in the circle of Willis arteries during operations on the brachiocephalic arteries and in heart operations].

    Science.gov (United States)

    Kuntsevich, G I; Kaĭdash, A N; Ter-Khachaturova, I E; Kovalevskaia, O A

    1995-01-01

    The paper gives the results of arterial blood flow monitoring in the circle of Willis via transcranial Doppler during 81 reparative operations on brachiocephalic arteries (including carotid endarterectomy from the internal carotid artery in 32 patients). Transcranial monitoring of blood flow supports the fact that there is a collateral reflow along the cerebral arteries during removal of the common carotid artery and that there is a relationship between the status of great arteries and arteries of Willis' circle. The paper also summaries the results of a comprehensive ultrasound study of 9 patients who have undergone reparative and plastic operations on the cardiac valves during extracorporeal circulation and general hypothermia. Blood flow was intraoperatively monitored in the arteries of the basis cerebri by using transcranial duplex scanning with colour Doppler flow mapping to evaluate not only hemodynamics, but also the embolic situation, as well as to check up how air was removed from the cardiac cavities by transesophageal echocardiography.

  20. Tethered Satellites as an Enabling Platform for Operational Space Weather Monitoring Systems

    Science.gov (United States)

    Gilchrist, Brian E.; Krause, Linda Habash; Gallagher, Dennis Lee; Bilen, Sven Gunnar; Fuhrhop, Keith; Hoegy, Walt R.; Inderesan, Rohini; Johnson, Charles; Owens, Jerry Keith; Powers, Joseph; Voronka, Nestor; Williams, Scott

    2013-01-01

    Tethered satellites offer the potential to be an important enabling technology to support operational space weather monitoring systems. Space weather "nowcasting" and forecasting models rely on assimilation of near-real-time (NRT) space environment data to provide warnings for storm events and deleterious effects on the global societal infrastructure. Typically, these models are initialized by a climatological model to provide "most probable distributions" of environmental parameters as a function of time and space. The process of NRT data assimilation gently pulls the climate model closer toward the observed state (e.g., via Kalman smoothing) for nowcasting, and forecasting is achieved through a set of iterative semi-empirical physics-based forward-prediction calculations. Many challenges are associated with the development of an operational system, from the top-level architecture (e.g., the required space weather observatories to meet the spatial and temporal requirements of these models) down to the individual instruments capable of making the NRT measurements. This study focuses on the latter challenge: we present some examples of how tethered satellites (from 100s of m to 20 km) are uniquely suited to address certain shortfalls in our ability to measure critical environmental parameters necessary to drive these space weather models. Examples include long baseline electric field measurements, magnetized ionospheric conductivity measurements, and the ability to separate temporal from spatial irregularities in environmental parameters. Tethered satellite functional requirements are presented for two examples of space environment observables.

  1. An Operational System For Monitoring Oil Spills In The Mediterranean Sea: The PROMED System

    Directory of Open Access Journals (Sweden)

    I. KERAMITSOGLOU

    2012-12-01

    Full Text Available The primary objective of this work was the development of an operational system for early detection of oil-spills, monitoring of their evolution, and provision of support to responsible Public Authorities during cleanup operations, based on Remote Sensing and GIS technologies. In case of emergency, the principal characteristics of the oil spill are defined with the aid of a space-borne synthetic aperture radar (SAR. The transport, spreading and dispersion of the oil spill is subsequently simulated on the basis of wind forecasts of the area. The use of thematic maps of protected, fishing and urban areas, and regions of high tourism allows the better assessment of the impact of an oil spill on the areas to be affected in terms of environmental sensitivity. Finally, reports are generated notifying port authorities, the media, and local organizations to be potentially affected by the presence of the oil spill. The pilot site for testing the PROMED System in Greece is the island of Crete.

  2. [Unexpected atrial fibrillation when monitoring in operating room. Case of the trimester].

    Science.gov (United States)

    2014-05-01

    A real case reported to the SENSAR database of incidents is presented. In a patient scheduled for nose fracture repair surgery an unexpected atrial fibrillation was found when monitored in the operating room. The operation was not delayed. After induction of general anaesthesia heart rate suddenly increased and hemodinamic situation was impaired. Cardioversion was required. Two electric countershocks were given but sinus rhythm was not restored. Heart rate was controlled with amiodarone infusion. Optimal defibrillation characteristics are described in these cases. Increased risk of thromboembolism (1-2%) following cardioversion is present even if atrial thrombi are ruled out. The mainstay therapies of are rhythm and rate control and prevention of thromboembolic complications. We describe recommendations on the management of these critical situations with emphasis in learning through the creation of protocols and training practice in simulation. Copyright © 2013 Sociedad Española de Anestesiología, Reanimación y Terapéutica del Dolor. Published by Elsevier España. All rights reserved.

  3. In situ monitoring of animal micronuclei before the operation of Daya Bay Nuclear Power Station

    Energy Technology Data Exchange (ETDEWEB)

    Y.N. Cai; H.Y. He; L.M. Qian; G.C. Sun; J.Y. Zhao [Guangzhou College of Education, Guangzhou (China)

    1994-12-31

    Daya Bay Nuclear Power Station, a newly-built nuclear power station in southern mainland China, started its operation in 1993. We examined micro-nucleated cells of Invertibrate (Bivalves) and Vertibrate (Fish and Amphibia) in different spots within the 50km surroundings of the Power Station during 1986-1993. This paper reports the results of the investigation carried out in Dong Shan, a place 4.7km to the Power Station:Bivalves; Pteria martensil 5.1(1986),4.8(1988),4.8(1991),5,0(1993),Mytilus smardinus 4.7(1987),4.6(1988); Chamys nobilis 4.9(1987);4.9(1991),4.5(1992),4.5(1993). Fish; Therapon jarbua 0.48(1991),0.67(1992),0.47(1993). Amphibia; Bufo melanostictus 0.29 (1987), 0.34(1988),0.39(1992),0.39(1993). These results showed that the environmental situation, estimated by using the frequencies of micronucleated cells, was stable-there was no obvious chromosome damage in the animals studied. It was found that the incidence of micronucleated cells of Bivalves was higher than that of Fish and Amphibia, suggesting the epithelial cells to be more sensitive than peripheral erythrocytes to environmental genotoxic effects. The results of our studies for other spots will be reported afterward. These data can be used as the original background information to monitor the environment when the Nuclear Power Station is in operation.

  4. Preliminary Concept of Operations for a Global Cylinder Identification and Monitoring System

    Energy Technology Data Exchange (ETDEWEB)

    Whitaker, J. M. [ORNL; White-Horton, J. L. [ORNL; Morgan, J. B. [InSolves Associates

    2013-08-01

    This report describes a preliminary concept of operations for a Global Cylinder Identification and Monitoring System that could improve the efficiency of the International Atomic Energy Agency (IAEA) in conducting its current inspection activities and could provide a capability to substantially increase its ability to detect credible diversion scenarios and undeclared production pathways involving UF6 cylinders. There exist concerns that a proliferant State with access to enrichment technology could obtain a cylinder containing natural or low-enriched uranium hexafluoride (UF6) and produce a significant quantity (SQ)1 of highly enriched uranium in as little as 30 days. The National Nuclear Security Administration (NNSA) through the Next Generation Safeguards Initiative sponsored a multi-laboratory team to develop an integrated system that provides for detecting scenarios involving 1) diverting an entire declared cylinder for enrichment at a clandestine facility, 2) misusing a declared cylinder at a safeguarded facility, and 3) using an undeclared cylinder at a safeguarded facility. An important objective in developing this integrated system was to improve the timeliness for detecting the cylinder diversion and undeclared production scenarios. Developing this preliminary concept required in-depth analyses of current operational and safeguards practices at conversion, enrichment, and fuel fabrication facilities. The analyses evaluated the processing, movement, and storage of cylinders at the facilities; the movement of cylinders between facilities (including cylinder fabrication); and the misuse of safeguarded facilities.

  5. An Operational System For Monitoring Oil Spills In The Mediterranean Sea: The PROMED System

    Directory of Open Access Journals (Sweden)

    I. KERAMITSOGLOU

    2003-12-01

    Full Text Available The primary objective of this work was the development of an operational system for early detection of oil-spills, monitoring of their evolution, and provision of support to responsible Public Authorities during cleanup operations, based on Remote Sensing and GIS technologies. In case of emergency, the principal characteristics of the oil spill are defined with the aid of a space-borne synthetic aperture radar (SAR. The transport, spreading and dispersion of the oil spill is subsequently simulated on the basis of wind forecasts of the area. The use of thematic maps of protected, fishing and urban areas, and regions of high tourism allows the better assessment of the impact of an oil spill on the areas to be affected in terms of environmental sensitivity. Finally, reports are generated notifying port authorities, the media, and local organizations to be potentially affected by the presence of the oil spill. The pilot site for testing the PROMED System in Greece is the island of Crete.

  6. Air quality monitoring of the post-operative recovery room and locations surrounding operating theaters in a medical center in Taiwan.

    Science.gov (United States)

    Tang, Chin-Sheng; Wan, Gwo-Hwa

    2013-01-01

    To prevent surgical site infection (SSI), the airborne microbial concentration in operating theaters must be reduced. The air quality in operating theaters and nearby areas is also important to healthcare workers. Therefore, this study assessed air quality in the post-operative recovery room, locations surrounding the operating theater area, and operating theaters in a medical center. Temperature, relative humidity (RH), and carbon dioxide (CO2), suspended particulate matter (PM), and bacterial concentrations were monitored weekly over one year. Measurement results reveal clear differences in air quality in different operating theater areas. The post-operative recovery room had significantly higher CO2 and bacterial concentrations than other locations. Bacillus spp., Micrococcus spp., and Staphylococcus spp. bacteria often existed in the operating theater area. Furthermore, Acinetobacter spp. was the main pathogen in the post-operative recovery room (18%) and traumatic surgery room (8%). The mixed effect models reveal a strong correlation between number of people in a space and high CO2 concentration after adjusting for sampling locations. In conclusion, air quality in the post-operative recovery room and operating theaters warrants attention, and merits long-term surveillance to protect both surgical patients and healthcare workers.

  7. Air quality monitoring of the post-operative recovery room and locations surrounding operating theaters in a medical center in Taiwan.

    Directory of Open Access Journals (Sweden)

    Chin-Sheng Tang

    Full Text Available To prevent surgical site infection (SSI, the airborne microbial concentration in operating theaters must be reduced. The air quality in operating theaters and nearby areas is also important to healthcare workers. Therefore, this study assessed air quality in the post-operative recovery room, locations surrounding the operating theater area, and operating theaters in a medical center. Temperature, relative humidity (RH, and carbon dioxide (CO2, suspended particulate matter (PM, and bacterial concentrations were monitored weekly over one year. Measurement results reveal clear differences in air quality in different operating theater areas. The post-operative recovery room had significantly higher CO2 and bacterial concentrations than other locations. Bacillus spp., Micrococcus spp., and Staphylococcus spp. bacteria often existed in the operating theater area. Furthermore, Acinetobacter spp. was the main pathogen in the post-operative recovery room (18% and traumatic surgery room (8%. The mixed effect models reveal a strong correlation between number of people in a space and high CO2 concentration after adjusting for sampling locations. In conclusion, air quality in the post-operative recovery room and operating theaters warrants attention, and merits long-term surveillance to protect both surgical patients and healthcare workers.

  8. Air Quality Monitoring of the Post-Operative Recovery Room and Locations Surrounding Operating Theaters in a Medical Center in Taiwan

    Science.gov (United States)

    Tang, Chin-Sheng; Wan, Gwo-Hwa

    2013-01-01

    To prevent surgical site infection (SSI), the airborne microbial concentration in operating theaters must be reduced. The air quality in operating theaters and nearby areas is also important to healthcare workers. Therefore, this study assessed air quality in the post-operative recovery room, locations surrounding the operating theater area, and operating theaters in a medical center. Temperature, relative humidity (RH), and carbon dioxide (CO2), suspended particulate matter (PM), and bacterial concentrations were monitored weekly over one year. Measurement results reveal clear differences in air quality in different operating theater areas. The post-operative recovery room had significantly higher CO2 and bacterial concentrations than other locations. Bacillus spp., Micrococcus spp., and Staphylococcus spp. bacteria often existed in the operating theater area. Furthermore, Acinetobacter spp. was the main pathogen in the post-operative recovery room (18%) and traumatic surgery room (8%). The mixed effect models reveal a strong correlation between number of people in a space and high CO2 concentration after adjusting for sampling locations. In conclusion, air quality in the post-operative recovery room and operating theaters warrants attention, and merits long-term surveillance to protect both surgical patients and healthcare workers. PMID:23573296

  9. Role of the N-linked glycans of the prM and E envelope proteins in tick-borne encephalitis virus particle secretion.

    Science.gov (United States)

    Goto, Akiko; Yoshii, Kentarou; Obara, Mayumi; Ueki, Tomotaka; Mizutani, Tetsuya; Kariwa, Hiroaki; Takashima, Ikuo

    2005-04-27

    The tick-borne encephalitis (TBE) virus has two membrane glycoproteins (prM and E), which each has one N-linked glycan. Constructs that express prM and E proteins of TBE virus have been shown to produce virus-like particles (VLPs), which have surface properties that are similar to those of infectious viruses. To reveal the function of glycosylation of the TBE virus prM and E proteins in the secretion of VLPs, we expressed glycosylation-mutated prM and E proteins and compared the secretion levels and biological properties of the VLPs. In the prM protein glycosylation-deficient mutant, the level of secreted E protein was reduced to 60% of the wild-type level. On the other hand, in the E or prM-E protein glycosylation-deficient mutant, the level of secreted E protein was reduced to 10% of the wild-type level. Furthermore, the mutant which was glycosylated at positions 66 and 154 in protein E, the level of secreted E protein was four-fold higher than that of the wild-type. However, in the mutant which was glycosylated at position 66 only, E protein secretion was reduced to only 10% of the wild-type level. These data suggest that the glycan associated with the N-linked glycosylation site at position 154 in protein E plays an important role in VLP secretion.

  10. Automation of PRM-dependent D3-Leu tracer enrichment in HDL to study the metabolism of apoA-I, LCAT and other apolipoproteins.

    Science.gov (United States)

    Lee, Lang Ho; Andraski, Allison B; Pieper, Brett; Higashi, Hideyuki; Sacks, Frank M; Aikawa, Masanori; Singh, Sasha A

    2017-01-01

    We developed an automated quantification workflow for PRM-enabled detection of D3-Leu labeled apoA-I in high-density lipoprotein (HDL) isolated from humans. Subjects received a bolus injection of D3-Leu and blood was drawn at eight time points over three days. HDL was isolated and separated into six size fractions for subsequent proteolysis and PRM analysis for the detection of D3-Leu signal from ∼0.03 to 0.6% enrichment. We implemented an intensity-based quantification approach that takes advantage of high-resolution/accurate mass PRM scans to identify the D3-Leu 2HM3 ion from non-specific peaks. Our workflow includes five modules for extracting the targeted PRM peak intensities (XPIs): Peak centroiding, noise removal, fragment ion matching using Δm/z windows, nine intensity quantification options, and validation and visualization outputs. We optimized the XPI workflow using in vitro synthesized and clinical samples of D0/D3-Leu labeled apoA-I. Three subjects' apoA-I enrichment curves in six HDL size fractions, and LCAT, apoA-II and apoE from two size fractions were generated within a few hours. Our PRM strategy and automated quantification workflow will expedite the turnaround of HDL apoA-I metabolism data in clinical studies that aim to understand and treat the mechanisms behind dyslipidemia.

  11. Towards operational rainfall monitoring with microwave links from cellular telecommunication networks

    Science.gov (United States)

    Overeem, Aart; Leijnse, Hidde; Uijlenhoet, Remko

    2017-04-01

    The basic principle of rainfall estimation using microwave links is as follows. Rainfall attenuates the electromagnetic signals transmitted from one telephone tower to another. By measuring the received power at one end of a microwave link as a function of time, the path-integrated attenuation due to rainfall can be calculated, which can be converted to average rainfall intensities over the length of a link. Microwave links from cellular communication networks have been proposed as a promising new rainfall measurement technique since one decade. They are particularly interesting for those countries where few surface rainfall observations are available. Yet too date no operational (real-time) link-based rainfall products are available. To advance the process towards operational application and upscaling of this technique, long time series should be analyzed for different networks and climates. Here the potential for long-term large-scale operational rainfall monitoring is demonstrated by utilizing a 2.5-year data set from a cellular communication network. The data set consists of roughly 2,000 links covering the land surface of the Netherlands (35,500 square kilometers). The quality of link rainfall maps is thoroughly quantified by an extensive validation against independent gauge-adjusted radar rainfall maps for, among others, different seasons and extremes. One of the goals is to quantify whether the cellular telecommunication network can yield rainfall maps of comparable quality as those based on automatic rain gauge data (with a density of 1 gauge per 1000 square kilometers). Developing countries will usually have rain gauge networks with a lower density (and little or no weather radars). This helps to assess the possibly added value of link-based rainfall estimates with respect to those from existing rain gauge networks. Moreover, this shows the possibly added value of link rainfall estimates for adjustment of radar rainfall images. The results further confirm

  12. Monitoring millimeter wave stray radiation during ECRH operation at ASDEX Upgrade

    Directory of Open Access Journals (Sweden)

    Wagner D.

    2012-09-01

    Full Text Available Due to imperfection of the single path absorption, ECRH at ASDEX Upgrade (AUG is always accompanied by stray radiation in the vacuum vessel. New ECRH scenarios with O2 and X3 heating schemes extend the operational space, but they have also the potential to increase the level of stray radiation. There are hazards for invessel components. Damage on electric cables has already been encountered. It is therefore necessary to monitor and control the ECRH with respect to the stray radiation level. At AUG a system of Sniffer antennas equipped with microwave detection diodes is installed. The system is part of the ECRH interlock circuit. We notice, however, that during plasma operation the variations of the Sniffer antenna signal are very large. In laboratory measurements we see variations of up to 20 dB in the directional sensitivity and we conclude that an interference pattern is formed inside the copper sphere of the antenna. When ECRH is in plasma operation at AUG, the plasma is acting as a phase and mode mixer for the millimeter waves and thus the interference pattern inside the sphere changes with the characteristic time of the plasma dynamics. In order to overcome the difficulty of a calibrated measurement of the average stray radiation level, we installed bolometer and pyroelectric detectors, which intrinsically average over interference structures due to their large active area. The bolometer provides a robust calibration but with moderate temporal resolution. The pyroelectric detector provides high sensitivity and a good temporal resolution, but it raises issues of possible signal drifts in long pulses.

  13. A computational model for knowledge-driven monitoring of nuclear power plant operators based on information theory

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Man Cheol [Department of Nuclear and Quantum Engineering, Korea Advanced Institute of Science and Technology, 373-1, Guseong-dong, Yuseong-gu, Daejeon 305-701 (Korea, Republic of)]. E-mail: charleskim@kaist.ac.kr; Seong, Poong Hyun [Department of Nuclear and Quantum Engineering, Korea Advanced Institute of Science and Technology, 373-1, Guseong-dong, Yuseong-gu, Daejeon 305-701 (Korea, Republic of)

    2006-03-15

    To develop operator behavior models such as IDAC, quantitative models for the cognitive activities of nuclear power plant (NPP) operators in abnormal situations are essential. Among them, only few quantitative models for the monitoring and detection have been developed. In this paper, we propose a computational model for the knowledge-driven monitoring, which is also known as model-driven monitoring, of NPP operators in abnormal situations, based on the information theory. The basic assumption of the proposed model is that the probability that an operator shifts his or her attention to an information source is proportional to the expected information from the information source. A small experiment performed to evaluate the feasibility of the proposed model shows that the predictions made by the proposed model have high correlations with the experimental results. Even though it has been argued that heuristics might play an important role on human reasoning, we believe that the proposed model can provide part of the mathematical basis for developing quantitative models for knowledge-driven monitoring of NPP operators when NPP operators are assumed to behave very logically.

  14. A computational model for knowledge-driven monitoring of nuclear power plant operators based on information theory

    Energy Technology Data Exchange (ETDEWEB)

    Man Cheol Kim; Poong Hyun Seong [Korea Advanced Institute of Science and Technology, Daejeon (Korea). Department of Nuclear and Quantum Engineering

    2006-03-15

    To develop operator behavior models such as IDAC, quantitative models for the cognitive activities of nuclear power plant (NPP) operators in abnormal situations are essential. Among them, only few quantitative models for the monitoring and detection have been developed. In this paper, we propose a computational model for the knowledge-driven monitoring, which is also known as model-driven monitoring, of NPP operators in abnormal situations, based on the information theory. The basic assumption of the proposed model is that the probability that an operator shifts his or her attention to an information source is proportional to the expected information from the information source. A small experiment performed to evaluate the feasibility of the proposed model show that the predictions made by the proposed model have high correlations with the experimental results. Even though it has been argued that heuristics might play an important role on human reasoning, we believe that the proposed model can provide part of the mathematical basis for developing quantitative models for knowledge-driven monitoring of NPP operators when NPP operators are assumed to behave very logically. (author)

  15. Comprehensive mapping infection-enhancing epitopes of dengue pr protein using polyclonal antibody against prM.

    Science.gov (United States)

    Luo, Yayan; Guo, Xiaolan; Yan, Huijun; Fang, Danyun; Zeng, Gucheng; Zhou, Junmei; Jiang, Lifang

    2015-07-01

    Dengue vaccine development is considered a global public health priority, but the antibody-dependent enhancement (ADE) issues have critically restricted vaccine development. Recent findings have demonstrated that pre-membrane (prM) protein was involved in dengue virus (DENV) infection enhancement. Although the importance of prM antibodies have been well characterized, only a few epitopes in DENV prM protein have ever been identified. In this study, we screened five potential linear epitopes located at positions pr1 (1-16aa), pr3 (13-28aa), pr4 (19-34aa), pr9 (49-64aa), and pr10 (55-70aa) in pr protein using peptide scanning and comprehensive bioinformatics analysis. Then, we found that only pr4 (19-34aa) could elicit high-titer antibodies in Balb/c mice, and this epitope could react with sera from DENV2-infected patients, suggesting that specific antibodies against epitope peptide pr4 were elicited in both DENV-infected mice and human. In addition, our data demonstrated that anti-pr4 sera showed limited neutralizing activity but significant ADE activity toward standard DENV serotypes and imDENV. Hence, it seems responsible to hypothesize that anti-pr4 serum was infection-enhancing antibody and pr4 was infection-enhancing epitope. In conclusion, we characterized a novel infection-enhancing epitope on dengue pr protein, a finding that may provide new insight into the pathogenesis of DENV infection and contribute to dengue vaccine design.

  16. Single point mutation in tick-borne encephalitis virus prM protein induces a reduction of virus particle secretion

    OpenAIRE

    Yoshii, Kentarou; Konno, Akihiro; Goto, Akiko; Nio, Junko; Obara, Mayumi; Ueki, Tomotaka; Hayasaka, Daisuke; Mizutani, Tetsuya; Kariwa, Hiroaki; Takashima, Ikuo

    2004-01-01

    Flaviviruses are assembled to bud into the lumen of the endoplasmic reticulum (ER) and are secreted through the vesicle transport pathway. Virus envelope proteins play important roles in this process. In this study, the effect of mutations in the envelope proteins of tick-borne encephalitis (TBE) virus on secretion of virus-like particles (VLPs), using a recombinant plasmid expression system was analysed. It was found that a single point mutation at position 63 in prM induces a reduction in s...

  17. Cost Effective, Ultra Sensitive Groundwater Monitoring for Site Remediation and Management: Standard Operating Procedures with QA/QC

    Science.gov (United States)

    2015-05-01

    GUIDANCE DOCUMENT Cost-Effective, Ultra-Sensitive Groundwater Monitoring for Site Remediation and Management: Standard Operating Procedures... Groundwater Monitoring for Site Remediation and Management 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Halden, R.U., Roll, I.B. 5d...DEPLOYMENT WORK As with any groundwater sampling method, the decision to apply the IS2 technology is based on the site characteristics and the type

  18. In situ radiation test of silicon and diamond detectors operating in superfluid helium and developed for beam loss monitoring

    Science.gov (United States)

    Kurfürst, C.; Dehning, B.; Sapinski, M.; Bartosik, M. R.; Eisel, T.; Fabjan, C.; Rementeria, C. A.; Griesmayer, E.; Eremin, V.; Verbitskaya, E.; Zabrodskii, A.; Fadeeva, N.; Tuboltsev, Y.; Eremin, I.; Egorov, N.; Härkönen, J.; Luukka, P.; Tuominen, E.

    2015-05-01

    As a result of the foreseen increase in the luminosity of the Large Hadron Collider, the discrimination between the collision products and possible magnet quench-provoking beam losses of the primary proton beams is becoming more critical for safe accelerator operation. We report the results of ongoing research efforts targeting the upgrading of the monitoring system by exploiting Beam Loss Monitor detectors based on semiconductors located as close as possible to the superconducting coils of the triplet magnets. In practice, this means that the detectors will have to be immersed in superfluid helium inside the cold mass and operate at 1.9 K. Additionally, the monitoring system is expected to survive 20 years of LHC operation, resulting in an estimated radiation fluence of 1×1016 proton/cm2, which corresponds to a dose of about 2 MGy. In this study, we monitored the signal degradation during the in situ irradiation when silicon and single-crystal diamond detectors were situated in the liquid/superfluid helium and the dependences of the collected charge on fluence and bias voltage were obtained. It is shown that diamond and silicon detectors can operate at 1.9 K after 1×1016 p/cm2 irradiation required for application as BLMs, while the rate of the signal degradation was larger in silicon detectors than in the diamond ones. For Si detectors this rate was controlled mainly by the operational mode, being larger at forward bias voltage.

  19. Neurophysiologic monitoring of mental workload and fatigue during operation of a flight simulator

    Science.gov (United States)

    Smith, Michael E.; Gevins, Alan

    2005-05-01

    In one experiment, EEG recordings were made during a daytime session while 16 well-rested participants performed versions of a PC flight simulator task that were either low, moderate, or high in difficulty. In another experiment, the same subjects repeatedly performed high difficulty versions of the same task during an all night session with total sleep deprivation. Multivariate EEG metrics of cortical activation were derived for frontal brain regions essential for working memory and executive control processes that are presumably important for maintaining situational awareness, central brain regions essential for sensorimotor control, and posterior parietal and occipital regions essential for visuoperceptual processing. During the daytime session each of these regional measures displayed greater activation during the high difficulty task than during the low difficulty task, and degree of cortical activation was positively correlated with subjective workload ratings in these well-rested subjects. During the overnight session, cortical activation declined with time-on-task, and the degree of this decline over frontal regions was negatively correlated with subjective workload ratings. Since participants were already highly skilled in the task, such changes likely reflect fatigue-related diminishment of frontal executive capability rather than practice effects. These findings suggest that the success of efforts to gauge mental workload via proxy cortical activation measures in the context of adaptive automation systems will likely depend on use of user models that take both task demands and the operator"s state of alertness into account. Further methodological development of the measurement approach outlined here would be required to achieve a practical, effective objective means for monitoring transient changes in cognitive brain function during performance of complex real-world tasks.

  20. Spinal pain management. The role of physical and rehabilitation medicine physicians. The European perspective based on the best evidence. A paper by the UEMS-PRM Section Professional Practice Committee.

    Science.gov (United States)

    Valero, R; Varela, E; Küçükdeveci, A A; Oral, A; Ilieva, E; Berteanu, M; Christodoulou, N

    2013-10-01

    One of the objectives of the Professional Practice Committee (PPC) of the Physical and Rehabilitation Medicine (PRM) Section of the Union of European Medical Specialists (UEMS) is the development of the field of competence of PRM physicians in Europe. To achieve this objective, UEMS PRM Section PPC has adopted a systematic action plan of preparing a series of papers describing the role of PRM physicians in a number of disabling health conditions, based on the evidence of effectiveness of the PRM interventions. The aim of this paper is to describe the role of PRM physicians in the management of spinal pain focusing particularly on low back pain and neck pain. These disorders are associated with significant disability that results in activity limitations and participation restrictions. A wide variety of PRM interventions including patient education, behavioural therapies, exercise, a number of physical modalities, manual techniques, and multidisciplinary rehabilitation may help patients with low back pain and cervical pain in improving their functioning. PRM physicians may address many of the problems encountered by these patients in many life areas taking the International Classification of Functioning, Disability and Health as a reference guide and may have an important role in improving the quality of their lives.

  1. Monitoring the anaesthetist in the operating theatre - professional competence and patient safety.

    Science.gov (United States)

    Larsson, J

    2017-01-01

    This article about competence and patient safety in anaesthesia was inspired by a statement in the 2015 AAGBI guidelines on monitoring during anaesthesia: 'the presence of an appropriately trained and experienced anaesthetist is important for patient safety during anaesthesia'. The review starts with a structured description of competence, presenting five dimensions of it; the first two dimensions are identical with the two classical attributes of competence, practical skills and theoretical knowledge. Concerning skills, the value of aiming for a high level of proficiency early in a traning programme is pointed out, and deliberate practice is given as an example of a pedagogical model where aiming for excellence is a core idea. For theoretical knowledge, the value of a deep approach to learning physiology and basic sciences is stressed. The third dimension (anaesthetists' non-technical skills), represents skills necessary for good team-work in the operating theatre. The two last dimensions of competence are the understanding of work and intuitive expert knowing. Understanding work means being aware of what the work is about, appreciating the different aspects of the anaesthetist's job. Intuitive expert knowing, lastly, concerns the tacit dimension of knowledge and skills, which enables professional experts to quickly find a working solution for most clinical problems. The final part of the review is about the 'when' and 'how' of competence assessment. The main message is the importance of assessing the competence of clinically active anaesthetists regularly during their whole career. © 2017 The Association of Anaesthetists of Great Britain and Ireland.

  2. Operational evaluation of the Mediterranean Monitoring and Forecasting Centre products: implementation and results

    Science.gov (United States)

    Tonani, M.; Nilsson, J. A. U.; Lyubartsev, V.; Grandi, A.; Aydogdu, A.; Azzopardi, J.; Bolzon, G.; Bruschi, A.; Drago, A.; Garau, T.; Gatti, J.; Gertman, I.; Goldman, R.; Hayes, D.; Korres, G.; Lorente, P.; Malacic, V.; Mantziafou, A.; Nardone, G.; Olita, A.; Ozsoy, E.; Pairaud, I.; Pensieri, S.; Perivoliotis, L.; Petelin, B.; Ravaioli, M.; Renault, L.; Sofianos, S.; Sotillo, M. G.; Teruzzi, A.; Zodiatis, G.

    2012-04-01

    A web-based validation platform has been developed at the Istituto Nazionale di Geofisica e Vulcanologia (INGV) for the Near Real Time validation of the MyOcean-Mediterranean Monitoring and Forecasting Centre products (Med-MFC). A network for the collection of the in-situ observations, the nested sub-basin forecasting systems model data (provided by the partners of the Mediterranean Operational Oceanography Network, MOON) and the Sea Surface Temperature (SST) satellite data has been developed and is updated every day with the new available data. The network collects temperature, salinity, currents and sea level data. The validation of the biogeochemical forecast products is done by use of ocean colour satellite data produced for the Mediterranean Sea. All the data are organized in an ad hoc database interfaced with a dedicated software which allows interactive visualizations and statistics (CalVal SW). This tool allows to evaluate NRT products by comparison with independent observations for the first time. The heterogeneous distribution and the scarcity of moored observations reflect with large areas uncovered with measurements. Nevertheless, the evaluation of the forecast at the locations of observations could be very useful to discover sub-regions where the model performances can be improved, thus yielding an important complement to the basin-mean statistics regularly calculated for the Mediterranean MFC products using semi-independent observations.

  3. Monitoring radionuclides in subsurface drinking water sources near unconventional drilling operations: a pilot study.

    Science.gov (United States)

    Nelson, Andrew W; Knight, Andrew W; Eitrheim, Eric S; Schultz, Michael K

    2015-04-01

    Unconventional drilling (the combination of hydraulic fracturing and horizontal drilling) to extract oil and natural gas is expanding rapidly around the world. The rate of expansion challenges scientists and regulators to assess the risks of the new technologies on drinking water resources. One concern is the potential for subsurface drinking water resource contamination by naturally occurring radioactive materials co-extracted during unconventional drilling activities. Given the rate of expansion, opportunities to test drinking water resources in the pre- and post-fracturing setting are rare. This pilot study investigated the levels of natural uranium, lead-210, and polonium-210 in private drinking wells within 2000 m of a large-volume hydraulic fracturing operation--before and approximately one-year following the fracturing activities. Observed radionuclide concentrations in well waters tested did not exceed maximum contaminant levels recommended by state and federal agencies. No statistically-significant differences in radionuclide concentrations were observed in well-water samples collected before and after the hydraulic fracturing activities. Expanded monitoring of private drinking wells before and after hydraulic fracturing activities is needed to develop understanding of the potential for drinking water resource contamination from unconventional drilling and gas extraction activities. Copyright © 2015 Elsevier Ltd. All rights reserved.

  4. Design and Operation of a Radiative Bhabha Luminosity Monitor for CESR-c

    CERN Document Server

    Palmer, Mark A; Crede, Volker; Dooley, Katherine L; Napalitano, James; Rubin, David; Smith, Jeffrey C; Vogel, Helmut

    2005-01-01

    The CLEO-c experiment at the Cornell Electron Storage Ring (CESR) is presently embarking on a multi-year exploration of charm and QCD physics in the 3-5 GeV center-of-mass energy range. In order to facilitate rapid optimization of machine parameters over this energy range, a luminosity monitor based on the measurement of radiative-bhabha photons coming from the CLEO-c interaction point (IP) has been designed and installed in the CESR ring. Key design criteria of the device include: better than 1% statistical measurements of the luminosity with a 1 Hz update rate over the full range of CESR-c operating conditions; bunch-by-bunch measurement capability; a large horizontal aperture to enable measurements under conditions ranging from single-bunch head-on collisions to multi-bunch collisions with a horizontal crossing angle of up to 4~mrad; and, a segmented readout to provide direct information on beam characteristics at the IP. We review the design and performance of this device and discuss its application to ma...

  5. Commissioning and first operation of the pCVD diamond ATLAS Beam Conditions Monitor

    CERN Document Server

    Dobos, D

    2009-01-01

    The main aim of the ATLAS Beam Conditions Monitor is to protect the ATLAS Inner Detector silicon trackers from high radiation doses caused by LHC beam incidents, e.g. magnet failures. The BCM uses in total 16 1x1 cm2 500 μm thick polycrystalline chemical vapor deposition (pCVD) diamond sensors. They are arranged in 8 positions around the ATLAS LHC interaction point. Time difference measurements with sub nanosecond resolution are performed to distinguish between particles from a collision and spray particles from a beam incident. An abundance of the latter leads the BCM to provoke an abort of the LHC beam. A FPGA based readout system with a sampling rate of 2.56 GHz performs the online data analysis and interfaces the results to ATLAS and the beam abort system. The BCM diamond sensors, the detector modules and their readout system are described. Results of the operation with the first LHC beams are reported and results of commissioning and timing measurements (e.g. with cosmic muons) in preparation for first ...

  6. Monitoring of operation with artificial intelligence methods; Betriebsueberwachung mit Verfahren der Kuenstlichen Intelligenz

    Energy Technology Data Exchange (ETDEWEB)

    Bruenninghaus, H. [DMT-Gesellschaft fuer Forschung und Pruefung mbH, Essen (Germany). Geschaeftsbereich Systemtechnik

    1999-03-11

    Taking the applications `early detection of fires` and `reduction of burst of messages` as an example, the usability of artificial intelligence (AI) methods in the monitoring of operation was checked in a R and D project. The contribution describes the concept, development and evaluation of solutions to the specified problems. A platform, which made it possible to investigate different AI methods (in particular artificial neuronal networks), had to be creaated as a basis for the project. At the same time ventilation data had to be acquired and processed by the networks for the classification. (orig.) [Deutsch] Am Beispiel der Anwendungsfaelle `Brandfrueherkennung` und `Meldungsschauerreduzierung` wurde im Rahmen eines F+E-Vorhabens die Einsetzbarkeit von Kuenstliche-Intelligenz-Methoden (KI) in der Betriebsueberwachung geprueft. Der Beitrag stellt Konzeption, Entwicklung und Bewertung von Loesungsansaetzen fuer die genannten Aufgabenstellungen vor. Als Grundlage fuer das Vorhaben wurden anhand KI-Methoden (speziell: Kuenstliche Neuronale Netze -KNN) auf der Grundlage gewonnener und aufbereiteter Wetterdaten die Beziehungen zwischen den Wettermessstellen im Laufe des Wetterwegs klassifiziert. (orig.)

  7. A WEB-BASED SOLUTION TO VISUALIZE OPERATIONAL MONITORING LINUX CLUSTER FOR THE PROTODUNE DATA QUALITY MONITORING CLUSTER

    CERN Document Server

    Mosesane, Badisa

    2017-01-01

    The Neutrino computing cluster made of 300 Dell PowerEdge 1950 U1 nodes serves an integral role to the CERN Neutrino Platform (CENF). It represents an effort to foster fundamental research in the field of Neutrino physics as it provides data processing facility. We cannot begin to over emphasize the need for data quality monitoring coupled with automating system configurations and remote monitoring of the cluster. To achieve these, a software stack has been chosen to implement automatic propagation of configurations across all the nodes in the cluster. The bulk of these discusses and delves more into the automated configuration management system on this cluster to enable the fast online data processing and Data Quality (DQM) process for the Neutrino Platform cluster (npcmp.cern.ch).

  8. Evaluación de híbridos experimentales de maíz del PRM en Cenroamérica.

    OpenAIRE

    Guerra, Fidencio; Fuentes, Mario; Cruz, Oscar; Espinoza, Alberto; Pixley, Leopoldo; Camargo-Buitrago, Ismael; Castellanos, Salvador

    2003-01-01

    El ensayo de híbridos experimentalesblancos del PRM-2001, fue evaluado durante el año 2001en 14 localidades de Centroamérica. El objetivo de este trabajofue evaluar el rendimiento de grano y características agronómicas de los híbridos experimentales. Doce híbridos triples,uno doble, formados con cruzas simples de CIMMYT ylíneas superiores de diferentes proyectos del Programa Regionalde Maíz (PRM) principalmente de híbridos y achaparramiento,incluida una entrada de referencia (CML 247 x CML254...

  9. Evaluación de híbridos experimentales de maíz del PRM en Centroamérica

    OpenAIRE

    Fidencio Guerra; Mario Fuentes; Oscar Cruz; Alberto Espinoza; Leopoldo Pixley; Ismael Camargo; Salvador Castellanos

    2003-01-01

    El ensayo de híbridos experimentales blancos del PRM-2001, fue evaluado durante el año 2001 en 14 localidades de Centroamérica. El objetivo de este trabajo fue evaluar el rendimiento de grano y características agron ómicas de los híbridos experimentales. Doce híbridos triples, uno doble, formados con cruzas simples de CIMMYT y líneas superiores de diferentes proyectos del Programa Regional de Maíz (PRM) principalmente de híbridos y achaparramiento, incluida una entrada...

  10. Histidine at residue 99 and the transmembrane region of the precursor membrane prM protein are important for the prM-E heterodimeric complex formation of Japanese encephalitis virus.

    Science.gov (United States)

    Lin, Ying-Ju; Wu, Suh-Chin

    2005-07-01

    The formation of the flavivirus prM-E complex is an important step for the biogenesis of immature virions, which is followed by a subsequent cleavage of prM to M protein through cellular protease to result in the production and release of mature virions. In this study, the intracellular formation of the prM-E complex of Japanese encephalitis virus was investigated by baculovirus coexpression of prM and E in trans in Sf9 insect cells as analyzed by anti-E antibody immunoprecipitation and sucrose gradient sedimentation analysis. A series of carboxyl-terminally truncated prM mutant baculoviruses was constructed to demonstrate that the truncations of the transmembrane (TM) region resulted in a reduction of the formation of the stable prM-E complex by approximately 40% for the TM1 (at residues 130 to 147 [prM130-147]) truncation and 20% for TM2 (at prM153-167) truncation. Alanine-scanning site-directed mutagenesis on the prM99-103 region indicated that the His99 residue was the critical prM binding element for stable prM-E heterodimeric complex formation. The single amino acid mutation at the His99 residue of prM abolishing the prM-E interaction was not due to reduced expression or different subcellular location of the mutant prM protein involved in prM-E interactions as characterized by pulse-chase labeling and confocal scanning microscopic analysis. Recombinant subviral particles were detected in the Sf9 cell culture supernatants by baculovirus coexpression of prM and E proteins but not with the prM H99A mutant. Sequence alignment analysis was further conducted with different groups of flaviviruses to show that the prM H99 residues are generally conserved. Our findings are the first report to characterize the minimum binding elements of the prM protein that are involved in prM-E interactions of flaviviruses. This information, concerning a molecular framework for the prM protein, is considered to elucidate the structure/function relationship of the prM-E complex

  11. GTRI Remote Monitoring System: Training and Operational Needs Assessment Analysis Report

    Energy Technology Data Exchange (ETDEWEB)

    Day, Debra E.; Fox, Sorcha

    2012-04-20

    The mission of the United States Department of Energy (DOE) National Nuclear Security Administrations (NNSA's) Global Threat Reduction Initiative (GTRI) is to identify, secure, recover and facilitate the disposition of vulnerable nuclear and high-risk radioactive materials around the world that pose a threat to the United States and the international community. The GTRI's unique mission to reduce and protect vulnerable nuclear and radiological materials located at civilian sites worldwide directly addresses recommendations of the 9/11 Commission1, and is a vital part of the President's National Security Strategy and the Global Initiative. The GTRI Remote Monitoring System (RMS) is a standalone security system that includes radiation and tamper alarms, and CCTV; which can be transmitted securely over the Internet to multiple on-site and off-site locations. Through our experiences during installation of the system at 162 sites, plus feedback received from Alarm Response Training course participants, site input to project teams and analysis of trouble calls; indications were that current system training was lacking and inconsistent. A survey was undertaken to gather information from RMS users across the nation, to evaluate the current level of training and determine what if any improvements needed to be made. Additional questions were focused on the operation of the RMS software. The training survey was initially sent electronically to 245 users at the RMS sites and achieved a 37.6% return rate. Analysis of the resulting data revealed that 34.6% of the respondents had not received training or were unsure if they had, despite the fact that vendor engineers provide training at installation of the system. Any training received was referred to as minimal, and brief, not documented, and nothing in writing. 63.7% of respondents said they were either not at all prepared or only somewhat prepared to use the RMS software required to effectively operate the

  12. 杜比PRM-4200带来经济高效的后期体验

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    2012年3月,杜比实验室正式宣布广受认可的杜比PRM-4200专业视频效果测试校正仪现已在大中华地区上市。杜比PRM-4200专业视频效果测试校正仪是首款基于平板的测试校正仪,能够精确的呈现出真正的黑电平,使整个色域具有卓越的暗部细节和更高的对比度。这款视频效果测试校正仪的推出,为创作者提供了更精准的画质效果,同时也将后期制作流程变得更加高效灵活。

  13. Novel robust approach for constructing Mamdani-type fuzzy system based on PRM and subtractive clustering algorithm

    Institute of Scientific and Technical Information of China (English)

    褚菲; 马小平; 王福利; 贾润达

    2015-01-01

    A novel approach for constructing robust Mamdani fuzzy system was proposed, which consisted of an efficiency robust estimator (partial robust M-regression, PRM) in the parameter learning phase of the initial fuzzy system, and an improved subtractive clustering algorithm in the fuzzy-rule-selecting phase. The weights obtained in PRM, which gives protection against noise and outliers, were incorporated into the potential measure of the subtractive cluster algorithm to enhance the robustness of the fuzzy rule cluster process, and a compact Mamdani-type fuzzy system was established after the parameters in the consequent parts of rules were re-estimated by partial least squares (PLS). The main characteristics of the new approach were its simplicity and ability to construct fuzzy system fast and robustly. Simulation and experiment results show that the proposed approach can achieve satisfactory results in various kinds of data domains with noise and outliers. Compared with D-SVD and ARRBFN, the proposed approach yields much fewer rules and less RMSE values.

  14. RCRA and Operational Monitoring (ROM). Multi-Year Program Plan and Fiscal Year 95 Work Plan WBS 1.5.3

    Energy Technology Data Exchange (ETDEWEB)

    1994-09-17

    This document contains information concerning the RCRA and Operational Monitoring Program at Hanford Reservation. Information presented includes: Schedules for ground water monitoring activities, program cost baseline, program technical baseline, and a program milestone list.

  15. Environmental Monitoring Plan, United States Department of Energy, Richland Operations Office. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    1994-11-09

    This report describes environmental monitoring activities at Hanford Reservation. Attention is focused on effluent monitoring and environmental surveillance. All Hanford contractors reviewed potential sources of contamination. A facility effluent monitoring plan was written for each facility with the potential to release significant quantities of hazardous materials, addressing both radiological and nonradiological effluent monitoring. The environmental surveillance program assesses onsite and offsite environmental impacts and offsite human health exposures. The program monitors air, surface water, sediment, agricultural products, vegetation, soil, and wildlife. In addition, independent onsite surveillance is conducted to evaluate the effectiveness of Hanford Site effluent controls in order to comply with applicable environmental standards and regulations.

  16. DEVELOPMENT, INSTALLATION AND OPERATION OF THE MPC&A OPERATIONS MONITORING (MOM) SYSTEM AT THE JOINT INSTITUTE FOR NUCLEAR RESEARCH (JINR) DUBNA, RUSSIA

    Energy Technology Data Exchange (ETDEWEB)

    Kartashov,V.V.; Pratt,W.; Romanov, Y.A.; Samoilov, V.N.; Shestakov, B.A.; Duncan, C.; Brownell, L.; Carbonaro, J.; White, R.M.; Coffing, J.A.

    2009-07-12

    The Material Protection, Control and Accounting (MPC&A) Operations Monitoring (MOM) systems handling at the International Intergovernmental Organization - Joint Institute for Nuclear Research (JINR) is described in this paper. Category I nuclear material (plutonium and uranium) is used in JINR research reactors, facilities and for scientific and research activities. A monitoring system (MOM) was installed at JINR in April 2003. The system design was based on a vulnerability analysis, which took into account the specifics of the Institute. The design and installation of the MOM system was a collaborative effort between JINR, Brookhaven National Laboratory (BNL) and the U.S. Department of Energy (DOE). Financial support was provided by DOE through BNL. The installed MOM system provides facility management with additional assurance that operations involving nuclear material (NM) are correctly followed by the facility personnel. The MOM system also provides additional confidence that the MPC&A systems continue to perform effectively.

  17. Enterprise risk management in international construction operations

    CERN Document Server

    Zhao, Xianbo; Low, Sui Pheng

    2015-01-01

    This book provides readers an understanding of the implementation of Enterprise Risk Management (ERM) for international construction operations. In an extended case study, it primarily focuses on Chinese construction firms (CCFs) based in Singapore. In this regard, the book explains the differences and similarities between Risk Management (RM), Project Risk Management (PRM) and ERM in the construction industry, and examines their linkages for international construction operations in a broader context. The explanation elaborates on how companies may adopt and implement RM, PRM and ERM as appropriate in their various operations, both in their home market as well as in overseas host markets. The book also reviews the whole spectrum of work relating to organizational behavior (OB) as one of the key underpinnings for companies to evaluate and implement ERM. It will benefit practitioners from the industry as well as academics interested in the implementation of ERM practices in international construction operat...

  18. 40 CFR Table 5 to Subpart Ppp of... - Process Vents From Batch Unit Operations-Monitoring, Recordkeeping, and Reporting Requirements

    Science.gov (United States)

    2010-07-01

    ... Hazardous Air Pollutant Emissions for Polyether Polyols Production Pt. 63, Subpt. PPP, Table 5 Table 5 to... all instances when monitoring data are not collected—PR. d,e If a base absorbent is used, report all pH values that are below the minimum operating values. If an acid absorbent is used, report all...

  19. 40 CFR 63.4568 - What are the requirements for continuous parameter monitoring system installation, operation, and...

    Science.gov (United States)

    2010-07-01

    ... caused in part by poor maintenance or careless operation are not malfunctions. Any period for which the... install a device to monitor pressure drop across the zeolite wheel or rotary carbon bed. The pressure... simulations or via relative accuracy testing. (v) Conduct an accuracy audit every quarter and after every...

  20. Transatrial access for left atrial pressure (LAP) monitoring line placement in arterial switch operation (ASO) in neonates.

    Science.gov (United States)

    Akhtar, Mohammad Irfan; Hamid, Mohammad; Amanullah, Muneer; Ahsan, Khalid

    2013-11-01

    Left Atrial pressure monitoring is a useful and accurate method to guide Left ventricle filling in the patients who undergo Arterial switch operation for transposition of great arteries. We have used a different technique in three TGA patients for LA pressure monitoring line placement. After cleaning and draping,right internal jugular vein (rt IJV) located through 22G venous cannula, guide wire was put in followed by sliding the 22G x 8cm vygon arterial catheter over the guide wire into the right atrium that was directed transatrially into LA by the operating surgeon during atrial septum repair. The catheter was secured by silk on the neck and dressed with transparent dressing and was kept for a period of 48-72 hrs. LA pressure monitoring is helpful in anticipating LV dysfunction in ASO.

  1. Inflammatory arthritis. The role of physical and rehabilitation medicine physicians. The European perspective based on the best evidence. A paper by the UEMS-PRM Section Professional Practice Committee.

    Science.gov (United States)

    Küçükdeveci, A A; Oral, A; Ilıeva, E M; Varela, E; Valero, R; Berteanu, M; Chrıstodoulou, N

    2013-08-01

    One of the objectives of the Professional Practice Committee (PPC) of the Physical and Rehabilitation Medicine (PRM) Section of the Union of European Medical Specialists (UEMS) is the development of the field of competence of PRM physicians in Europe. To achieve this objective, UEMS PRM Section PPC has adopted a systematic action plan of preparing a series of papers describing the role of PRM physicians in a number of disabling health conditions, based on the evidence of effectiveness of the physical and rehabilitation medicine interventions. Inflammatory arthritis is a major cause of disability with an important economic burden in society. The goals in the management of inflammatory arthritis are to control pain and disease activity, prevent joint damage, protect and enhance function and improve quality of life. This paper aims to define the role of PRM physicians in people with inflammatory arthritis. PRM interventions imply non-pharmacological treatments which include patient education for joint protection, energy conservation and self-management techniques, exercise therapy, physical modalities, orthoses/assistive devices and balneotherapy. Therapeutic patient education and exercises are the cornerstones of therapy with strong evidence of their effectiveness to improve function. Physical modalities are primarily used to decrease pain and stiffness whereas orthoses/assistive devices are usually prescribed to enhance activities and participation. PRM physicians have distinct roles in the management of people with inflammatory arthritis such that they effectively organise and supervise the PRM program in the context of interdisciplinary team work. Their role starts with a comprehensive assessment of patient's functioning based on the International Classification of Functioning Disability and Health (ICF) as the framework. In the light of this assessment, appropriate PRM interventions individualised for the patient are administered. Future research and actions

  2. Response monitoring and action limits: use of ADC numbers in understanding the operational characteristics of the Beckman ASTRA chemistry system.

    Science.gov (United States)

    Kessner, A; Burnett, R W; Bowers, G N

    1981-07-01

    The Beckman ASTRA is a microprocessor-controlled multichannel chemistry analyzer. The output of each module is available to the operator as analog-to-digital conversion (ADC) numbers, which we record during each calibration (Response Monitoring). After so studying three instruments for a total of 33 months, we have established limits for Calibrator ADC numbers that indicate possible operator action (Action Limits). These Action Limits are tighter than the microprocessor's programmed limits, and alert the operator to short- and long-term drift. These tighter limits warn of (a) impending failure of the instrument to calibrate or (b) possible inaccuracies in results for patients. We have instituted changes in preventive maintenance based on our studies of each module's operational characteristics, and have replaced electrodes that failed to meet our Response Monitoring specifications. Response Monitoring and Action Limits based upon ADC numbers have significantly enhanced our understanding of the ASTRA system and thus improved its operational efficiency and analytical reliability. Estimates of precision and accuracy (true value) were satisfactory in comparison to our prior single-channel continuous-flow and flame photometry analytical measurement systems.

  3. Monitoring the clean-up operation of agricultural fields flooded with red mud in Hungary.

    Science.gov (United States)

    Uzinger, Nikolett; Rékási, Márk; Anton, Áron D; Koós, Sándor; László, Péter; Anton, Attila

    2016-12-01

    In the course of the clean-up operation after the red mud inundation in 2010, red mud was removed from the soil surface in places where the layer was more than 5 cm deep. Before its removal, the red mud seeped into the soil. In 2012, soil samples were taken from depths of 0 to 20 and 20 to 40 cm on some of the affected areas. The parameters investigated were pH, organic matter, salt%, and the total and mobile fractions of various elements. The values recorded in 2012 were compared with those measured immediately after the removal of the red mud in 2010 and with the background and clean-up target concentrations. The pH values remained below the designated limit, while the salt content only exhibited values in the weakly salty range on areas at the greatest distance from the dam. In the central part of the inundated area, total Na contents above the 900 mg/kg target value were observed, but the Na content in the 0-20-cm layer generally exhibited a decrease due to leaching. The pH and As concentration also showed a decline on several areas compared with the values recorded in 2010. Total As and Co contents in excess of the target values were recorded on the lowest-lying part of the flooded area, probably because the finest red mud particles were deposited the furthest from the dam, where they seeped into the soil. Nevertheless, the mobility and plant availability of both elements remained moderate. The total contents of both Co and Mo, however, exhibited a significant rise compared with both the background value and the 2010 data. The monitoring of the cleaned-up areas showed that after a 2-year period element concentrations that exceeded the target values and could be attributed to the red mud pollution were only detectable on the lowest-lying areas.

  4. Post-operative monitoring of cortical taurine in patients with subarachnoid hemorrhage: a microdialysis study.

    Science.gov (United States)

    De Micheli, E; Pinna, G; Alfieri, A; Caramia, G; Bianchi, L; Colivicchi, M A; Della Corte, L; Bricolo, A

    2000-01-01

    Intracerebral MD enables the retrieval of endogenous substances from the extracellular fluid (ECF) of the brain and has been demonstrated to be a sensitive technique for early detection of subtle vasospasm-induced neurometabolic abnormalities in patients with subarachnoid hemorrhage (SAH). The aim of this study was to monitor cortical extracellular concentrations of energy metabolism markers, such as glucose and lactate, neurotransmitter amino acids, such as glutamate, aspartate, GABA and taurine to identify any neurochemical patterns of cerebral ischemia. A prospective clinical study was conducted on a group of 16 patients with non-severe SAH operated on within 72 hours after initial bleeding. Following aneurysm clipping, an MD catheter was inserted in the cortical region where vasospasm could be expected to develop, and perfused with artificial CSF at 0.3 microl/min flow rate. Dialysate was collected every 6 hours and then analyzed on High Performance Liquid Cromatography (HPLC) for glucose, lactate, pyruvate, glutamate, aspartate, GABA and taurine. Mean ECF taurine concentrations ranged from 1.4 + 0.7 to 12.3 + 7.8 micromol/l in single patients: global mean value was 5.8 + 3.8 micromol/l. In this series, the highest absolute taurine value was 25.7 micromol/l, observed in a patient who developed clinical and radiological signs of cerebral ischemia. Nine patients presented clinical disturbances related to cerebral vasospasm. In this setting, representing a mild-to-moderate hypoxic condition, MD data demonstrated that lactate is the most sensitive marker of cellular energy imbalance. Increased lactate levels positively correlated with glutamate (P<0.0001), aspartate (P<0.0001), GABA (P<0.0001) and taurine (P<0.0001) concentrations. These results suggest that also in humans increased taurine levels reflect a condition of cellular stress. This study confirms that MD is a sensitive technique to reveal subtle metabolic abnormalities possibly resulting in cell damage.

  5. Adaptive Contingency Control: Wind Turbine Operation Integrated with Blade Condition Monitoring

    Data.gov (United States)

    National Aeronautics and Space Administration — We report here on first steps towards integrating systems health monitoring with adaptive contingency controls. In the scenario considered, the adaptive controller...

  6. Air monitoring of volatile organic compounds at relevant receptors during hydraulic fracturing operations in Washington County, Pennsylvania.

    Science.gov (United States)

    Maskrey, Joshua R; Insley, Allison L; Hynds, Erin S; Panko, Julie M

    2016-07-01

    A 3-month air monitoring study was conducted in Washington County, Pennsylvania, at the request of local community members regarding the potential risks resulting from air emissions of pollutants related to hydraulic fracturing operations. Continuous air monitoring for total volatile organic compounds was performed at two sampling sites, including a school and a residence, located within 900 m of a hydraulic fracturing well pad that had been drilled prior to the study. Intermittent 24-hour air samples for 62 individual volatile organic compounds were also collected. The ambient air at both sites was monitored during four distinct periods of unconventional natural gas extraction activity: an inactive period prior to fracturing operations, during fracturing operations, during flaring operations, and during another inactive period after operations. The results of the continuous monitoring during fracturing and flaring sampling periods for total volatile organic compounds were similar to the results obtained during inactive periods. Total volatile organic compound 24-hour average concentrations ranged between 0.16 and 80 ppb during all sampling periods. Several individual volatile compounds were detected in the 24-hour samples, but they were consistent with background atmospheric levels measured previously at nearby sampling sites and in other areas in Washington County. Furthermore, a basic yet conservative screening level evaluation demonstrated that the detected volatile organic compounds were well below health-protective levels. The primary finding of this study was that the operation of a hydraulic fracturing well pad in Washington County did not substantially affect local air concentrations of total and individual volatile organic compounds.

  7. Quantification of respiratory depression during pre-operative administration of midazolam using a non-invasive respiratory volume monitor

    Science.gov (United States)

    Gonzalez Castro, Luis N.; Mehta, Jaideep H.; Brayanov, Jordan B.; Mullen, Gary J.

    2017-01-01

    Background Pre-operative administration of benzodiazepines can cause hypoventilation—a decrease in minute ventilation (MV)—commonly referred to as “respiratory compromise or respiratory depression.” Respiratory depression can lead to hypercarbia and / or hypoxemia, and may heighten the risk of other respiratory complications. Current anesthesia practice often places patients at risk for respiratory complications even before surgery, as respiratory monitoring is generally postponed until the patient is in the operating room. In the present study we examined and quantified the onset of respiratory depression following the administration of a single dose of midazolam in pre-operative patients, using a non-invasive respiratory volume monitor that reports MV, tidal volume (TV), and respiratory rate (RR). Methods Impedance-based Respiratory Volume Monitor (RVM) data were collected and analyzed from 30 patients prior to undergoing orthopedic or general surgical procedures. All patients received 2.0 mg of midazolam intravenously at least 20 minutes prior to the induction of anesthesia and the effects of midazolam on the patient's respiratory function were analyzed. Results Within 15 minutes of midazolam administration, we noted a significant decrease in both MV (average decrease of 14.3% ± 5.9%, pbenzodiazepines affect primarily TV rather than RR. Such respiratory monitoring data provide the opportunity for individualizing dosing and adjustment of clinical interventions, especially important in elderly patients. With additional respiratory data, clinicians may be able to better identify and quantify respiratory depression, reduce adverse effects, and improve overall patient safety. PMID:28235069

  8. Searches for $p_{\\rm T}$ dependent fluctuations of flow angle and magnitude in Pb--Pb and p--Pb collisions

    DEFF Research Database (Denmark)

    Zhou, You

    2014-01-01

    Anisotropic azimuthal correlations are used to probe the properties and the evolution of the system created in heavy-ion collisions. Two-particle azimuthal correlations were used in the searches of $p_{\\rm T}$ dependent fluctuations of flow angle and magnitude, measured with the ALICE detector...

  9. Operation and performance of a National Monitoring Network for Radioactivity in Food

    NARCIS (Netherlands)

    Brandhoff, P.N.; Bourgondiën, van M.J.; Onstenk, C.G.M.; Vos van Avezathe, A.; Peters, R.J.B.

    2016-01-01

    In the Netherlands, the EU-mandated nationwide monitoring programme and emergency response plan for radioactivity in food is implemented by RIKILT (the Dutch institute for food safety) by means of the National Monitoring Network for Radioactivity in Food (LMRV). The LMRV consists of 48 individual

  10. Application of the quantitative oil monitoring to analysing the operating condition of marine machinery

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Based on the data of Fourier transform infra-red (FTIR) spectroscopy, spectrometric oilanalysis (SOA) and other routine methods, the experiment of oil monitoring for steering propellersis discussed. The experiment demonstrates the FTIR spectroscopy can rapidly and easily obtainthe results in laboratory analysis, and combine with spectrometer oil analysis, complementary in-formation is most effective to condition monitoring of marine machinery.

  11. Operation and performance of a National Monitoring Network for Radioactivity in Food

    NARCIS (Netherlands)

    Brandhoff, P.N.; Bourgondiën, van M.J.; Onstenk, C.G.M.; Vos van Avezathe, A.; Peters, R.J.B.

    2016-01-01

    In the Netherlands, the EU-mandated nationwide monitoring programme and emergency response plan for radioactivity in food is implemented by RIKILT (the Dutch institute for food safety) by means of the National Monitoring Network for Radioactivity in Food (LMRV). The LMRV consists of 48 individual

  12. 40 CFR 63.2269 - What are my monitoring installation, operation, and maintenance requirements?

    Science.gov (United States)

    2010-07-01

    ... Composite Wood Products Initial Compliance Requirements § 63.2269 What are my monitoring installation... moisture monitoring. For each furnish or veneer moisture meter, you must meet the requirements in... in the 25 to 35 percent (dry basis) moisture content range. For veneer redryers, use a...

  13. One-dimensional simulation of fire injection heights in contrasted meteorological scenarios with PRM and Meso-NH models

    Science.gov (United States)

    Strada, S.; Freitas, S. R.; Mari, C.; Longo, K. M.; Paugam, R.

    2013-02-01

    Wild-fires release huge amounts of aerosol and hazardous trace gases in the atmosphere. The residence time and the dispersion of fire pollutants in the atmosphere can range from hours to days and from local to continental scales. These various scenarios highly depend on the injection height of smoke plumes. The altitude at which fire products are injected in the atmosphere is controlled by fire characteristics and meteorological conditions. Injection height however is still poorly accounted in chemistry transport models for which fires are sub-grid scale processes which need to be parametrised. Only recently, physically-based approaches for estimating the fire injection heights have been developed which consider both the convective updrafts induced by the release of fire sensible heat and the impact of background meteorological environment on the fire convection dynamics. In this work, two different models are used to simulate fire injection heights in contrasted meteorological scenarios: a Mediterranean arson fire and two Amazonian deforestation fires. A Eddy-Diffusivity/Mass-Flux approach, formerly developed to reproduce convective boundary layer in the non-hydrostatic meteorological model Meso-NH, is compared to the 1-D Plume Rise Model. For both models, radiosonde data and re-analyses from the European Center for Medium-Range Weather Forecasts (ECMWF) have been used as initial conditions to explore the sensitivity of the models responses to different meteorological forcings. The two models predict injection heights for the Mediterranean fire between 1.7 and 3.3 km with the Meso-NH/EDMF model systematically higher than the 1-D PRM model. Both models show a limited sensitivity to the meteorological forcings with a 20-30% difference in the injection height between radiosondes and ECMWF data for this case. Injection heights calculated for the two Amazonian fires ranges from 5 to 6.5 km for the 1-D PRM model and from 2 to 4 km for the Meso-NH/EDMF model. The

  14. Low-dose ATRA Supplementation Abolishes PRM Formation in Rat Liver and Ameliorates Ethanol-induced Liver Injury

    Institute of Scientific and Technical Information of China (English)

    PAN Zhihong; DAN Zili; FU Yu; TANG Wangxian; LIN Jusheng

    2006-01-01

    The effects of all-trans-retinoic acid (ATRA) in low doses supplementation on concentrations of polar retinoid metabolites (PRM) and retinoids in the ethanol-fed rat liver, and on hepatocyte injury were investigated. The rat model of alcoholic liver disease (ALD) was induced by intragastric infusion of ethanol, and then the rats were administrated with ATRA in two different doses (150 μg/kg body weight and 1.5 mg/kg body weight) for 4 weeks. Concentrations of retinoids in rat liver and plasma were determined by using HPLC. Liver tissues pathologic changes were observed under the light microscopy and electron microscopy. The serum transaminases concentrations were measured. The results showed that the HPLC analysis of retinoids revealed that retinoids (vitamin A,RA, retinyl palmitate) concentrations in ethanol-fed rat liver and RA concentration in ethanol-fed rat plasma were markedly diminished (P<0.01) after ethanol feeding for 12 weeks. Furthermore, obvious peaks of PRM were formed in livers of ethanol-fed rats. ATRA 150 μg/kg supplementation in ethanol-fed rats for 4 weeks raised RA concentration in both liver and plasma, and also raised vitamin A concentration in liver to control levels, partially restored retinyl palmitate concentration (P<0.05) in liver. ATRA 1.5 mg/kg supplementation raised not only RA concentrations in liver and plasma but also retinyl palmitate concentrations in liver. However, the vitamin A concentration in liver of ATRA-supplemented rats (1.5 mg/kg) was higher than that of controls (P<0.05). The histologic observation of liver tissues indicated that ATRA treatment notably alleviated hepatocellular swelling,steatosis, the swelling of mitochondria and proliferation of smooth endoplasmic reticulum (SER).ATRA treatment greatly decreased levels of serum transaminases as compared with the only ethanol-fed group (P<0.05). It was concluded that low-dose ATRA treatment could restore retinoids concentrations and abolish the PRM formation

  15. One-dimensional simulation of fire injection heights in contrasted meteorological scenarios with PRM and Meso-NH models

    Directory of Open Access Journals (Sweden)

    S. Strada

    2013-02-01

    Full Text Available Wild-fires release huge amounts of aerosol and hazardous trace gases in the atmosphere. The residence time and the dispersion of fire pollutants in the atmosphere can range from hours to days and from local to continental scales. These various scenarios highly depend on the injection height of smoke plumes. The altitude at which fire products are injected in the atmosphere is controlled by fire characteristics and meteorological conditions. Injection height however is still poorly accounted in chemistry transport models for which fires are sub-grid scale processes which need to be parametrised. Only recently, physically-based approaches for estimating the fire injection heights have been developed which consider both the convective updrafts induced by the release of fire sensible heat and the impact of background meteorological environment on the fire convection dynamics. In this work, two different models are used to simulate fire injection heights in contrasted meteorological scenarios: a Mediterranean arson fire and two Amazonian deforestation fires. A Eddy-Diffusivity/Mass-Flux approach, formerly developed to reproduce convective boundary layer in the non-hydrostatic meteorological model Meso-NH, is compared to the 1-D Plume Rise Model. For both models, radiosonde data and re-analyses from the European Center for Medium-Range Weather Forecasts (ECMWF have been used as initial conditions to explore the sensitivity of the models responses to different meteorological forcings. The two models predict injection heights for the Mediterranean fire between 1.7 and 3.3 km with the Meso-NH/EDMF model systematically higher than the 1-D PRM model. Both models show a limited sensitivity to the meteorological forcings with a 20–30% difference in the injection height between radiosondes and ECMWF data for this case. Injection heights calculated for the two Amazonian fires ranges from 5 to 6.5 km for the 1-D PRM model and from 2 to 4 km for the Meso

  16. Development of a web-based monitoring system using operation parameters for the main component in nuclear power plants

    Energy Technology Data Exchange (ETDEWEB)

    Son, Dong Chan; An, Kung Il; Hong, Suk Young; Lee, Jeong Soo; Jung, Duk Jin; Shin, Sun Hee; Son, So Hee [Daesang Information Technology Co., Ltd., Seoul (Korea, Republic of)

    2004-02-15

    The frequency of the damage is increasing, which is caused by the fatigue, according to the increase of running of nuclear power plants. So we need to acquire the reliance of design data to estimate the fatigue and damage of major machinery that might happen as time-dependent crack growth characterization. The research is focused on keeping operating record of nuclear power plants about major machinery which consists of a nuclear reactor pressure boarder on each excessive operating condition including normal operating and extraordinary operating by estimating fracture mechanical movements on real time and fatigue about major nuclear power plants machinery, which are acquired the pressure and temperature data. For further details about the scope and contents of R and D are following. Development of H/W that is necessary to acquire operating real time data of heating and hydraulic power. Selection of a safety variable about major system by each type (the four NPP, all unit). Communication protocol development for connecting between CARE system data base server and fatigue monitoring system data base server. Development of connecting database for controlling and storing of heating and hydraulic power operating data. Real time monitoring system development based on Web using JAVA.

  17. Monitoring of EOR operations by electrical prospecting. 2; Denki tansaho ni yoru sekiyu kyosei kaishuho no monitoring. 2

    Energy Technology Data Exchange (ETDEWEB)

    Ushijima, K.; Mizunaga, H.; Tanaka, T.; Masuda, K. [Kyushu University, Fukuoka (Japan). Faculty of Engineering; Tamagawa, T. [Japex Jeoscience Institute, Tokyo (Japan)

    1996-10-01

    Fluid flow tomography (FFT) was applied to monitor the behavior of underground fluid in steam enhanced oil recovery (EOR) for oil sand reservoirs. FFT uses electrode arrangement of a mise-a-la-masse method, and continuously measures time variation in charged and spontaneous potential at various surface points to obtain realtime the images of underground seepage flow. It continuously measures ground surface potentials of 120 channels at intervals of 2s by applying alternative DC between a casing pipe and distant current electrode. It separates charged and spontaneous potential components, and converts them into time series data. It estimates the time and spacial distributions of seepage flow from time variation in spontaneous potential. It determines the change rate distribution of time-sliced apparent resistivity from charged potential to estimate the scale and area of seepage flow. As the experimental result, positive and negative electrodes in the change rate distribution were observed, and the direction connecting each electrode agreed with that of resistivity anomaly. FFT could observe realtime time variation in apparent resistivity due to steam injection. 9 refs., 7 figs.

  18. Two simple multivariate procedures for monitoring planetary gearboxes in non-stationary operating conditions

    Science.gov (United States)

    Zimroz, Radoslaw; Bartkowiak, Anna

    2013-07-01

    This paper deals with the diagnostics of planetary gearboxes under nonstationary operating conditions. In most diagnostics applications, energy of vibration signals (calculated directly from time series or extracted from spectral representation of signal) is used. Unfortunately energy based features are sensitive to load conditions and it makes diagnostics difficult. In this paper we used energy based 15D data vectors (namely spectral amplitudes of planetary mesh frequency and its harmonics) in order to investigate if it is possible to improve diagnostics efficiency in comparison to previous, one dimensional, approaches proposed for the same problem. Two multivariate methods, Principal Component Analysis (PCA) and Canonical Discriminant Analysis (CDA), were used as techniques for data analysis. We used these techniques in order to investigate dimensionality of the data and to visualize data in 3D and 2D spaces in order to understand data behavior and assess classification ability. As a case study the data from two planetary gearboxes used in complex mining machines (one in bad condition and the other in good condition) were analyzed. For these two machines more than 2000 15D vectors were acquired. It should be noted that due to non-stationarity of loading conditions, previous diagnostics results obtained using other techniques were moderately good (ca. 80% recognition efficiency); however there is still some need to improve diagnostics classification ability. After application of the proposed approaches it was found that the entire data could be reduced to 2 dimensions whereby data instances became visible and a good discriminant function (characterized by a misclassification rate of .0023, i.e. only 5 erroneous classifications for a total of 2183 instances) could be derived. This paper suggests a novel way for condition monitoring of planetary gearboxes based on multivariate statistics. The emphasis is put on the algebraic and geometric interpretations of the PCA

  19. Probe molecule (PrM) approach in adverse outcome pathway (AOP) based high-throughput screening (HTS): in vivo discovery for developing in vitro target methods.

    Science.gov (United States)

    Angrish, Michelle M; Madden, Michael C; Pleil, Joachim D

    2015-04-20

    Efficient and accurate adverse outcome pathway (AOP) based high-throughput screening (HTS) methods use a systems biology based approach to computationally model in vitro cellular and molecular data for rapid chemical prioritization; however, not all HTS assays are grounded by relevant in vivo exposure data. The challenge is to develop HTS assays with unambiguous quantitative links between in vitro responses and corresponding in vivo effects, which is complicated by metabolically insufficient systems, in vitro to in vivo extrapolation (IVIVE), cross-species comparisons, and other inherent issues correlating IVIVE findings. This article introduces the concept of ultrasensitive gas phase probe molecules (PrMs) to help bridge the current HTS assay IVIVE gap. The PrM concept assesses metabolic pathways that have already been well-defined from intact human or mammalian models. Specifically, the idea is to introduce a gas phase probe molecule into a system, observe normal steady state, add chemicals of interest, and quantitatively measure (from headspace gas) effects on PrM metabolism that can be directly linked back to a well-defined and corresponding in vivo effect. As an example, we developed the pharmacokinetic (PK) parameters and differential equations to estimate methyl tertiary butyl ether (MTBE) metabolism to tertiary butyl alcohol (TBA) via cytochrome (CYP) 2A6 in the liver from human empirical data. Because MTBE metabolic pathways are well characterized from in vivo data, we can use it as a PrM to explore direct and indirect chemical effects on CYP pathways. The PrM concept could be easily applied to in vitro and alternative models of disease and phenotype, and even test for volatile chemicals while avoiding liquid handling robotics. Furthermore, a PrM can be designed for any chemical with known empirical human exposure data and used to assess chemicals for which no information exists. Herein, we propose an elegant gas phase probe molecule-based approach to in

  20. 49 CFR 240.129 - Criteria for monitoring operational performance of certified engineers.

    Science.gov (United States)

    2010-10-01

    ... employs the skills to safely operate locomotives and/or trains, including the proper application of the... compliance with provisions of the railroad's operating rules, timetable or other mandatory directives that... operating rules, timetable or other mandatory directives violation of which by engineers were cited by...

  1. Operational GPS Imaging System at Multiple Scales for Earth Science and Monitoring of Geohazards

    Science.gov (United States)

    Blewitt, Geoffrey; Hammond, William; Kreemer, Corné

    2016-04-01

    Toward scientific targets that range from slow deep Earth processes to geohazard rapid response, our operational GPS data analysis system produces smooth, yet detailed maps of 3-dimensional land motion with respect to our Earth's center of mass at multiple spatio-temporal scales with various latencies. "GPS Imaging" is implemented operationally as a back-end processor to our GPS data processing facility, which uses JPL's GIPSY OASIS II software to produce positions from 14,000 GPS stations in ITRF every 5 minutes, with coordinate precision that gradually improves as latency increases upward from 1 hour to 2 weeks. Our GPS Imaging system then applies sophisticated signal processing and image filtering techniques to generate images of land motion covering our Earth's continents with high levels of robustness, accuracy, spatial resolution, and temporal resolution. Techniques employed by our GPS Imaging system include: (1) similarity transformation of polyhedron coordinates to ITRF with optional common-mode filtering to enhance local transient signal to noise ratio, (2) a comprehensive database of ~100,000 potential step events based on earthquake catalogs and equipment logs, (3) an automatic, robust, and accurate non-parametric estimator of station velocity that is insensitive to prevalent step discontinuities, outliers, seasonality, and heteroscedasticity; (4) a realistic estimator of velocity error bars based on subsampling statistics; (5) image processing to create a map of land motion that is based on median spatial filtering on the Delauney triangulation, which is effective at despeckling the data while faithfully preserving edge features; (6) a velocity time series estimator to assist identification of transient behavior, such as unloading caused by drought, and (7) a method of integrating InSAR and GPS for fine-scale seamless imaging in ITRF. Our system is being used to address three main scientific focus areas, including (1) deep Earth processes, (2

  2. Griffithsin binds to the glycosylated proteins (E and prM) of Japanese encephalitis virus and inhibit its infection.

    Science.gov (United States)

    Ishag, Hassan Z A; Li, Chen; Wang, Fengjuan; Mao, Xiang

    2016-04-02

    Griffithsin (GRFT) is a broad-spectrum antiviral protein against several glycosylated viruses. In our previous publication, we have shown that GRFT exerted antiviral activity against Japanese encephalitis virus (JEV) infection. Herein, we further elucidated the mechanism by which GRFT inhibits JEV infection in BHK-21 cells. In vitro experiments using Pull-down assay and Co-immunoprecipitation (CO-IP) assay showed that GRFT binds to the JEV glycosylated viral proteins, specifically the enveloped (E) and premature (prM) glycoproteins. The binding of GRFT to the JEV was competitively inhibited by increasing concentrations of mannose; in turns abolished anti-JEV activity of GRFT. We suggested that, the binding of GRFT to the glycosylated viral proteins may contribute to its anti-JEV activity. Collectively, our data indicated a possible mechanism by which GRFT exerted its anti-JEV activity. This observation suggests GRFT's potentials in the development of therapeutics against JEV or other flavivirus infection.

  3. 铁道车辆的磁阻电动机(PRM)和逆变器控制

    Institute of Scientific and Technical Information of China (English)

    神孫子博; 彭文生

    2001-01-01

    兼用永久磁铁的永磁辅助型磁阻电动机(PRM)是同步电动机的一种.简要介绍该型电动机的主要参数和控制系统的特点;重点论述电动机与控制装置组合试验的结果.确认系统控制稳定,再生制动时,由永久磁铁产生的感应电压不会导致什么问题.这种电动机可以取代现在的异步牵引电动机.

  4. The role of Environmental Health System air quality monitors in Space Station Contingency Operations

    Science.gov (United States)

    Limero, Thomas F.; Wilson, Steve; Perlot, Susan; James, John

    1992-01-01

    This paper describes the Space Station Freedom (SSF) Environmental Health System's air-quality monitoring strategy and instrumentation. A two-tier system has been developed, consisting of first-alert instruments that warn the crew of airborne contamination and a volatile organic analyzer that can identify volatile organic contaminants in near-real time. The strategy for air quality monitoring on SSF is designed to provide early detection so that the contamination can be confined to one module and so that crew health and safety can be protected throughout the contingency event. The use of air-quality monitors in fixed and portable modes will be presented as a means of following the progress of decontamination efforts and ensuring acceptable air quality in a module after an incident. The technology of each instrument will be reviewed briefly; the main focus of this paper, however, will be the use of air-quality monitors before, during, and after contingency incidents.

  5. Operational blueprint for inventory and monitoring on National Wildlife Refuges : Adapting to environmental change

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This blueprint describes how the National Wildlife Refuge System will initially implement a nationally coordinated program to support inventorying and monitoring...

  6. MONITORING OF ANTICOAGULATION IN APROTININ-TREATED PATIENTS DURING HEART OPERATION

    NARCIS (Netherlands)

    TABUCHI, N; NJO, TL; TIGCHELAAR, [No Value; HUYZEN, RJ; BOONSTRA, PW; VANOEVEREN, W

    1994-01-01

    Since aprotinin has become extensively used during cardiopulmonary bypass the maintenance of safe anticoagulation is a concern. Aprotinin affects anticoagulation measurement by the activated clotting time. Therefore, a reliable new measurement is needed to monitor anticoagulation during cardiopulmon

  7. Use of the Operational Air Quality Monitor (AQM) for In-Flight Water Testing Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Currently, the Air Quality Monitor (AQM) on-board ISS provides specific information for a number of target compounds in the air. However, there is a significant...

  8. US EPA Base Study Standard Operating Procedure for Continuous Monitoring of Outdoor Air

    Science.gov (United States)

    The procedure described is intended for monitoring continuously and simultaneously outdoor air quality parameters that are most commonly associated with indoor air quality: the concentrations of carbon dioxide (CO2) and carbon monoxide (CO), temperature, nd relative humidity (RH).

  9. Local soft tissue musculoskeletal disorders and injuries. The role of physical and rehabilitation medicine physicians. The European perspective based on the best evidence. A paper by the UEMS-PRM Section Professional Practice Committee.

    Science.gov (United States)

    Oral, A; Ilieva, E M; Küçükdeveci, A A; Varela, E; Valero, R; Berteanu, M; Christodoulou, N

    2013-10-01

    One of the objectives of the Professional Practice Committee (PPC) of the Physical and Rehabilitation Medicine (PRM) Section of the Union of European Medical Specialists (UEMS) is the development of the field of competence of PRM physicians in Europe. To achieve this objective, UEMS PRM Section PPC has adopted a systematic action plan of preparing a series of papers describing the role of PRM physicians in a number of disabling health conditions, based on the evidence of effectiveness of PRM interventions. Soft tissue musculoskeletal disorders (MSDs) and injuries are associated with significant pain and loss of function that may lead to significant disability. The aim of this paper is to define the role of PRM physician in the management of local soft tissue MSDs and injuries with their specific focus on assessing and improving function as well as participation in the community. The training of PRM specialists make them well equipped to successfully treat MSDs including soft tissue MSDs and injuries. PRM specialists may well meet the needs of patients with soft tissue MSDs and injuries using PRM approaches including 1) assessment based on the comprehensive model of functioning, the International Classification of Functioning, Disability and Health (ICF), that enable them to identify the areas of impaired functioning in order to apply necessary measures; 2) accurate diagnosis using instrumental diagnostic procedures in addition to clinical examination; 3) outcome measurements available to them; 4) evidence-based pharmacological and nonpharmacological treatments; and finally 5) maintenance of social involvement including "return to work" based on restoration of function, all of which will eventually result in improved quality of life for patients with soft tissue MSDs and injuries.

  10. GlobVolcano pre-operational services for global monitoring active volcanoes

    Science.gov (United States)

    Tampellini, Lucia; Ratti, Raffaella; Borgström, Sven; Seifert, Frank Martin; Peltier, Aline; Kaminski, Edouard; Bianchi, Marco; Branson, Wendy; Ferrucci, Fabrizio; Hirn, Barbara; van der Voet, Paul; van Geffen, J.

    2010-05-01

    The GlobVolcano project (2007-2010) is part of the Data User Element programme of the European Space Agency (ESA). The project aims at demonstrating Earth Observation (EO) based integrated services to support the Volcano Observatories and other mandate users (e.g. Civil Protection) in their monitoring activities. The information services are assessed in close cooperation with the user organizations for different types of volcano, from various geographical areas in various climatic zones. In a first phase, a complete information system has been designed, implemented and validated, involving a limited number of test areas and respective user organizations. In the currently on-going second phase, GlobVolcano is delivering pre-operational services over 15 volcanic sites located in three continents and as many user organizations are involved and cooperating with the project team. The set of GlobVolcano offered EO based information products is composed as follows: Deformation Mapping DInSAR (Differential Synthetic Aperture Radar Interferometry) has been used to study a wide range of surface displacements related to different phenomena (e.g. seismic faults, volcanoes, landslides) at a spatial resolution of less than 100 m and cm-level precision. Permanent Scatterers SAR Interferometry method (PSInSARTM) has been introduced by Politecnico of Milano as an advanced InSAR technique capable of measuring millimetre scale displacements of individual radar targets on the ground by using multi-temporal data-sets, estimating and removing the atmospheric components. Other techniques (e.g. CTM) have followed similar strategies and have shown promising results in different scenarios. Different processing approaches have been adopted, according to data availability, characteristic of the area and dynamic characteristics of the volcano. Conventional DInSAR: Colima (Mexico), Nyiragongo (Congo), Pico (Azores), Areanal (Costa Rica) PSInSARTM: Piton de la Fournaise (La Reunion Island

  11. Operational benefits obtained by implementing a remote monitoring and control system at CEGAS (Gas Company of Ceara, Brazil)

    Energy Technology Data Exchange (ETDEWEB)

    Almeida, Rui C.O. [Companhia de Gas do Ceara (CEGAS), Fortaleza, CE (Brazil); Zamponha, Rogerio S. [SOFTBRASIL, Sao Paulo, SP (Brazil)

    2009-07-01

    CEGAS (Gas Company of Ceara) recently implemented an automated remote monitoring and control system at the Natural Gas Stations located within the city of Fortaleza. The main purposes to implement the project were to install a better operational platform, allowing CEGAS to analyze its operational conditions and to measure customer's consumption in real time. The data communication infra-structure chosen was GPRS/GSM, due to it's low deployment cost and coverage availability. The first phase of the project comprised 50 vehicular natural gas stations. The project was successfully installed, and became the 1{sup st} project at this type to run efficiently over a GPRS infra-structure in Brazil for gas monitoring, with reliable control and data communication. This document intends to present the reasons that lead CEGAS to invest in such a system, the technology deployed and the benefits achieved. (author)

  12. Results of Continuous Load Cell Monitoring Field Trial for UF6 Withdrawals at an Operating Industrial Plant

    Energy Technology Data Exchange (ETDEWEB)

    Krichinsky, Alan M [ORNL; Bell, Lisa S [ORNL; Conchewski, Curtis A [ORNL; Peters, Benjamin R [ORNL; Pickett, Chris A [ORNL; Richardson, Dave [ORNL; Rowe, Nathan C [ORNL; Younkin, James R [ORNL

    2010-01-01

    Continuous load cell monitoring (CLCM) has been implemented and tested for use as a safeguards tool during a 2009 field trial in an operating UF6 transfer facility. The transfer facility is part of the Portsmouth Gaseous Diffusion Plant in Piketon, Ohio, operated by the United States Enrichment Corporation. During the field trial, two process scales for UF{sub 6} cylinders were continuously monitored for a 6-month period as cylinders were being filled. The collected CLCM data were used in testing an event processor serving as a filter for highlighting measurements representing significant operational activities that are important in verifying declared operations. The collection of CLCM data, coupled with rules-based event processing, can provide inspectors with knowledge of a facility's feed and withdrawal activities occurring between site visits. Such process knowledge promises to enhance the effectiveness of safeguards by enabling inspectors to quantitatively compare declared activities directly with process measurements. Selected results of the field trial and event processing will be presented in the context of their value to an independent inspector and a facility operator.

  13. Design and first operation of a supersonic gas jet based beam profile monitor

    Directory of Open Access Journals (Sweden)

    Vasilis Tzoganis

    2017-06-01

    Full Text Available Noninterceptive beam profile monitors are of great importance for many particle accelerators worldwide. Extra challenges are posed by high energy, high intensity machines and low energy low intensity accelerators. For these applications, existing diagnostics are no longer suitable due to the high power of the beam or the very low intensity. In addition, many other accelerators, from medical to industrial will benefit from a noninvasive, real time beam profile monitor. In this paper we present a new beam profile monitor with a novel design for the nozzle and skimmer configuration to generate a supersonic gas jet meeting ultrahigh vacuum conditions and we describe the first results for such a beam profile monitor at the Cockcroft Institute. This monitor is able to measure two-dimensional profiles of the particle beam while causing negligible disturbance to the beam or to the accelerator vacuum. The ultimate goal for this diagnostic is to provide a versatile and universal beam profile monitor suitable for measuring any beams.

  14. Federal Health Care Center: VA and DOD Need to Develop Better Information to Monitor Operations and Improve Efficiency

    Science.gov (United States)

    2017-01-01

    requirement to include two more reports, resulting in GAO reports in 2011, 2012, and 2016. 5GAO, VA and DOD Health Care: First Federal Health ...FEDERAL HEALTH CARE CENTER VA and DOD Need to Develop Better Information to Monitor Operations and Improve Efficiency...Government Accountability Office Highlights of GAO-17-197, a report to congressional committees January 2017 FEDERAL HEALTH CARE CENTER VA and DOD

  15. 在PRM上通过CS3000卡件读取现场HART仪表信息%Collecting Information of Field Hart Device Through CS3000’s Card on PRM

    Institute of Scientific and Technical Information of China (English)

    黄军政; 潘辉; 熊正

    2016-01-01

    本文介绍了工厂资源管理器(plant resource manager)(简称:PRM)在整个企业资产管理中所处的地位、作用,在此基础上给出了在PRM上通过CS3000网络读取现场HART仪表信息的方法。%This paper introduces position and function of plant resource manager(abbreviation:PRM), then presents method by which PRM can read information of HART instrument though cs3000’s network.

  16. Stibine/arsine monitoring during EV operation: summary report on preliminary tests at ANL and at LILCO

    Energy Technology Data Exchange (ETDEWEB)

    Loutfy, R.O.; Graczyk, D.G.; Varma, R.; Hayes, E.R.; Williams, F.L.; Yao, N.P.

    1981-02-01

    A series of tests was performed to monitor the evolution and dispersal of stibine and arsine from the lead-acid propulsion batteries in three different Electra-Van Model 600 vehicles operated by Argonne National Laboratory (ANL) and by the Long Island Lighting Company (LILCO). Ambient air was sampled at several locations inside the vehicles and in the garages where testing was done during charge, equalization charge, and on-the-road discharge operations. In addition, direct sampling of cell off-gases was performed with the ANL van. Interpretation of the individual test results was carried out in the context of vehicle characteristics, sampling protocol, and operating conditions. The test results demonstrated that under the test conditions only small concentrations of stibine and arsine accumulated in occupiable work areas. Measured concentrations in the vehicles and in the garages never exceeded 25% of the Threshold Limit Value-Time Weighted Average (TLV-TWA) standards. A threshold voltage for hydride production, at about 2.45 V per cell, was reflected in the results of the experiments performed during charging of the batteries. Hydride evolution rates were lower during equalization charge than during the overcharge portion of a charge cycle when the on-board charger was used in a normal operating mode. A delayed release of the metal hydrides from the battery cells was observed during on-the-road operation of the vehicles. The implications of these observations for electric vehicle (EV) operation are discussed. An engineering analysis of the generation and dispersal of the metal hydrides is presented, and equations are derived for estimating minimum ventilation requirements for the EV battery compartment and for garages housing EV operations. Recommendations are made regarding safe handling procedures for battery off-gases, procedures for conducting stibine/arsine monitoring tests and future work.

  17. Operational Monitoring of Mines by COSMO-SkyMed PSP SAR Interferometry

    Science.gov (United States)

    Costantini, Mario; Malvarosa, Fabio; Miniati, Federico; de Assis, Luciano Mozer

    2016-08-01

    Synthetic aperture radar (SAR) interferometry is a powerful technology for detection and monitoring of slow ground surface movements. Monitoring of ground deformations in mining structures is an important application, particularly difficult because the scene changes with time. The persistent scatterer pair (PSP) approach, recently proposed to overcome some limitations of standard persistent scatter interferometry, proved to be effective also for mine monitoring. In this work, after resuming the main ideas of the PSP method, we describe the PSP measurements obtained from high- resolution X-band COSMO-SkyMed data over a large mining area in Minas Gerais state, Brazil. The outcomes demonstrate that dense and accurate ground deformation measurements can be obtained on the mining area and its structures (such as open pits, waste dumps, conveyor belts, water and tailings dams, etc.), achieving a consistent global view including also areas where field instruments are not installed.

  18. In situ radiation test of silicon and diamond detectors operating in superfluid helium and developed for beam loss monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Kurfürst, C.; Dehning, B.; Sapinski, M.; Bartosik, M.R.; Eisel, T.; Fabjan, C.; Rementeria, C.A. [CERN, Geneva (Switzerland); Griesmayer, E. [CIVIDEC Instrumentation, GmbH, Vienna (Austria); Eremin, V. [Ioffe Institute, St. Petersburg (Russian Federation); Verbitskaya, E., E-mail: elena.verbitskaya@cern.ch [Ioffe Institute, St. Petersburg (Russian Federation); Zabrodskii, A.; Fadeeva, N.; Tuboltsev, Y.; Eremin, I. [Ioffe Institute, St. Petersburg (Russian Federation); Egorov, N. [Research Institute of Material Science and Technology, Zelenograd, Moscow (Russian Federation); Härkönen, J.; Luukka, P.; Tuominen, E. [Helsinki Institute of Physics, Helsinki (Finland)

    2015-05-11

    As a result of the foreseen increase in the luminosity of the Large Hadron Collider, the discrimination between the collision products and possible magnet quench-provoking beam losses of the primary proton beams is becoming more critical for safe accelerator operation. We report the results of ongoing research efforts targeting the upgrading of the monitoring system by exploiting Beam Loss Monitor detectors based on semiconductors located as close as possible to the superconducting coils of the triplet magnets. In practice, this means that the detectors will have to be immersed in superfluid helium inside the cold mass and operate at 1.9 K. Additionally, the monitoring system is expected to survive 20 years of LHC operation, resulting in an estimated radiation fluence of 1×10{sup 16} proton/cm{sup 2}, which corresponds to a dose of about 2 MGy. In this study, we monitored the signal degradation during the in situ irradiation when silicon and single-crystal diamond detectors were situated in the liquid/superfluid helium and the dependences of the collected charge on fluence and bias voltage were obtained. It is shown that diamond and silicon detectors can operate at 1.9 K after 1×10{sup 16} p/cm{sup 2} irradiation required for application as BLMs, while the rate of the signal degradation was larger in silicon detectors than in the diamond ones. For Si detectors this rate was controlled mainly by the operational mode, being larger at forward bias voltage. - Highlights: • Silicon and diamond detectors are proposed for beam loss monitoring at LHC. • The first in situ radiation test of Si and diamond detectors at 1.9 K is described. • Both diamond and silicon detectors survived after 1×10{sup 16} p/cm{sup 2} irradiation at 1.9 K. • The rate of Si detectors degradation depends on bias polarity and is larger at V{sub forw}. • Sensitivity of Si detectors irradiated to 1×10{sup 16} p/cm{sup 2} is independent on resistivity.

  19. 40 CFR 63.9921 - What are the installation, operation and maintenance requirements for my monitors?

    Science.gov (United States)

    2010-07-01

    ... ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS... operating limits in § 63.9890(b) for pressure drop and scrubber water flow rate, you must install, operate...) For the pressure drop CPMS, you must: (i) Locate the pressure sensor(s) in or as close to a position...

  20. Monitoring Attention During Operant Conditioning in Six and Seven Month Old Infants.

    Science.gov (United States)

    Strain, Barbara; Vietze, Peter M.

    The purpose of the present study was to investigate more directly the effects of content and repetition of contingent visual feedback on a discrete operant pulling response and accompanying visual attention in 24 six- to seven-month old infants. Simultaneous recording was made of infant operant behavior and visual attention. Results indicated…

  1. Performance Evaluation of the Operational Air Quality Monitor for Water Testing Aboard the International Space Station

    Science.gov (United States)

    Wallace, William T.; Limero, Thomas F.; Gazda, Daniel B.; Minton, John M.; Macatangay, Ariel V.; Dwivedi, Prabha; Fernandez, Facundo M.

    2014-01-01

    Real-time environmental monitoring on ISS is necessary to provide data in a timely fashion and to help ensure astronaut health. Current real-time water TOC monitoring provides high-quality trending information, but compound-specific data is needed. The combination of ETV with the AQM showed that compounds of interest could be liberated from water and analyzed in the same manner as air sampling. Calibration of the AQM using water samples allowed for the quantitative analysis of ISS archival samples. Some calibration issues remain, but the excellent accuracy of DMSD indicates that ETV holds promise for as a sample introduction method for water analysis in spaceflight.

  2. Self-Powered, Wireless, Remote Meteorologic Monitoring Based on Triboelectric Nanogenerator Operated by Scavenging Wind Energy.

    Science.gov (United States)

    Zhang, Hulin; Wang, Jie; Xie, Yuhang; Yao, Guang; Yan, Zhuocheng; Huang, Long; Chen, Sihong; Pan, Taisong; Wang, Liping; Su, Yuanjie; Yang, Weiqing; Lin, Yuan

    2016-12-07

    Meteorologic monitoring plays a key role on weather forecast and disaster warning and deeply relies on various sensor networks. It is an optimal choice that grabbing the environmental energy around sensors for driving sensor network. Here, we demonstrate a self-powered, wireless, remote meteorologic monitoring system based on an innovative TENG. The TENG has been proved capable of scavenging wind energy and can be employed for self-powered, wireless meteorologic sounding. This work not only promotes the development of renewable energy harvesting, but also exploits and enriches promising applications based on TENGs for self-powered, wireless, remote sensing.

  3. Operation and maintenance of thermal power stations best practices and health monitoring

    CERN Document Server

    Chanda, Pradip

    2016-01-01

    This book illustrates operation and maintenance practices/guidelines for economic generation and managing health of a thermal power generator beyond its regulatory life. The book provides knowledge for professionals managing power station operations, through its unique approach to chemical analysis of water, steam, oil etc. to identify malfunctioning/defects in equipment/systems much before the physical manifestation of the problem. The book also contains a detailed procedure for conducting performance evaluation tests on different equipment, and for analyzing test results for predicting maintenance requirements, which has lent a new dimension to power systems operation and maintenance practices. A number of real life case studies also enrich the book. This book will prove particularly useful to power systems operations professionals in the developing economies, and also to researchers and students involved in studying power systems operations and control. .

  4. Quantification of respiratory depression during pre-operative administration of midazolam using a non-invasive respiratory volume monitor.

    Science.gov (United States)

    Gonzalez Castro, Luis N; Mehta, Jaideep H; Brayanov, Jordan B; Mullen, Gary J

    2017-01-01

    Pre-operative administration of benzodiazepines can cause hypoventilation-a decrease in minute ventilation (MV)-commonly referred to as "respiratory compromise or respiratory depression." Respiratory depression can lead to hypercarbia and / or hypoxemia, and may heighten the risk of other respiratory complications. Current anesthesia practice often places patients at risk for respiratory complications even before surgery, as respiratory monitoring is generally postponed until the patient is in the operating room. In the present study we examined and quantified the onset of respiratory depression following the administration of a single dose of midazolam in pre-operative patients, using a non-invasive respiratory volume monitor that reports MV, tidal volume (TV), and respiratory rate (RR). Impedance-based Respiratory Volume Monitor (RVM) data were collected and analyzed from 30 patients prior to undergoing orthopedic or general surgical procedures. All patients received 2.0 mg of midazolam intravenously at least 20 minutes prior to the induction of anesthesia and the effects of midazolam on the patient's respiratory function were analyzed. Within 15 minutes of midazolam administration, we noted a significant decrease in both MV (average decrease of 14.3% ± 5.9%, pmidazolam administration on clinically significant respiratory parameters (MV, TV and RR) using a non-invasive RVM, uncovering that the respiratory depressive effect of benzodiazepines affect primarily TV rather than RR. Such respiratory monitoring data provide the opportunity for individualizing dosing and adjustment of clinical interventions, especially important in elderly patients. With additional respiratory data, clinicians may be able to better identify and quantify respiratory depression, reduce adverse effects, and improve overall patient safety.

  5. Performance Monitoring: Evaluating a Wheat Straw PRB for Nitrate Removal at an Agricultural Operation

    Science.gov (United States)

    The U.S. EPA Office of Research and Development’s National Risk Management Research Laboratory (NRMRL) is conducting long-term monitoring of a wheat straw permeable reactive barrier (PRB) for remediation of ground water contaminated with nitrate from a now-closed swine concentrat...

  6. Challenges and progress in making DNA-based monitoring operational AIS early detection as testbed

    Science.gov (United States)

    The ability of DNA barcoding to find additional species in hard-to-sample locations or hard-to-identify samples is well established. Nevertheless, adoption of DNA barcoding into regular monitoring programs has been slow, in part due to issues of standardization and interpretation...

  7. Challenges and progress in making DNA-based AIS early detection monitoring operational

    Science.gov (United States)

    The ability of DNA barcoding to find additional species in hard-to-sample locations or hard-to-identify samples is well established. Nevertheless, adoption of DNA barcoding into regular monitoring programs has been slow, in part due to issues of standardization and interpretation...

  8. Operational Forest Monitoring in Siberia Using Multi-source Earth Observation Data

    Directory of Open Access Journals (Sweden)

    C. Hüttich

    2014-08-01

    Full Text Available Forest cover disturbance rates are increasing in the forests of Siberia due to intensification of human activities and climate change. In this paper two satellite data sources were used for automated forest cover change detection. Annual ALOS PALSAR backscatter mosaics (2007–2010 were used for yearly forest loss monitoring. Time series of the Enhanced Vegetation Index (EVI, 2000–2014 from the Moderate Resolution Imaging Spectroradiometer (MODIS were integrated in a web-based data middleware system to assess the capabilities of a near-real time detection of forest disturbances using the break point detection by additive season and trends (Bfast method. The SAR-based average accuracy of the forest loss detection was 70 %, whereas the MODIS-based change assessment using breakpoint detection achieved average accuracies of 50 % for trend-based breakpoints and 43.4 % for season-based breakpoints. It was demonstrated that SAR remote sensing is a highly accurate tool for up-to-date forest monitoring. Web-based data middleware systems like the Earth Observation Monitor, linked with MODIS time series, provide access and easy-to-use tools for on demand change monitoring in remote Siberian forests.

  9. Use Of The Operational Air Quality Monitor (AQM) For In-Flight Water Testing Project

    Science.gov (United States)

    Macatangay, Ariel

    2014-01-01

    A primary requirement for manned spaceflight is Environmental Health which ensures air and water contaminants, acoustic profiles, microbial flora, and radiation exposures within the cabin are maintained to levels needed for crew health and for vehicle system functionality. The reliance on ground analyses of returned samples is a limitation in the current environmental monitoring strategy that will prevent future Exploration missions beyond low-Earth orbit. This proposal attempts to address this shortcoming by advancing in-flight analyses of water and air. Ground analysis of in-flight, air and water samples typically employ vapor-phase analysis by gas chromatography-mass spectrometry (GC-MS) to identify and quantify organic compounds present in the samples. We envision the use of newly-developed direct ionization approaches as the most viable avenue leading towards an integrated analytical platform for the monitoring of water, air, and, potentially bio-samples in the cabin environment. Development of an in-flight instrument capable of analyzing air and water samples would be the logical next step to meeting the environmental monitoring needs of Exploration missions. Currently, the Air Quality Monitor (AQM) on-board ISS provides this specific information for a number of target compounds in the air. However, there is a significant subset of common target compounds between air and water. Naturally, the following question arises, "Can the AQM be used for both air and water quality monitoring?" Previous directorate-level IR&D funding led to the development of a water sample introduction method for mass spectrometry using electrothermal vaporization (ETV). This project will focus on the integration of the ETV with a ground-based AQM. The capabilities of this integrated platform will be evaluated using a subset of toxicologically important compounds.

  10. 40 CFR 63.7831 - What are the installation, operation, and maintenance requirements for my monitors?

    Science.gov (United States)

    2010-07-01

    ... operating limits in § 63.7790(b)(2) for pressure drop and scrubber water flow rate, you must install... a manner consistent with the guidance document, “Fabric Filter Bag Leak Detection Guidance,”...

  11. 40 CFR 63.5545 - What are my monitoring installation, operation, and maintenance requirements?

    Science.gov (United States)

    2010-07-01

    ..., the pollutant concentration or parametric signal analyzer, and the data collection and reduction... must install, calibrate, and operate a flow indicator at the inlet or outlet of the control device to...

  12. A monitor for the laboratory evaluation of control integrity in digital control systems operating in harsh electromagnetic environments

    Science.gov (United States)

    Belcastro, Celeste M.; Fischl, Robert; Kam, Moshe

    1992-01-01

    This paper presents a strategy for dynamically monitoring digital controllers in the laboratory for susceptibility to electromagnetic disturbances that compromise control integrity. The integrity of digital control systems operating in harsh electromagnetic environments can be compromised by upsets caused by induced transient electrical signals. Digital system upset is a functional error mode that involves no component damage, can occur simultaneously in all channels of a redundant control computer, and is software dependent. The motivation for this work is the need to develop tools and techniques that can be used in the laboratory to validate and/or certify critical aircraft controllers operating in electromagnetically adverse environments that result from lightning, high-intensity radiated fields (HIRF), and nuclear electromagnetic pulses (NEMP). The detection strategy presented in this paper provides dynamic monitoring of a given control computer for degraded functional integrity resulting from redundancy management errors, control calculation errors, and control correctness/effectiveness errors. In particular, this paper discusses the use of Kalman filtering, data fusion, and statistical decision theory in monitoring a given digital controller for control calculation errors.

  13. Pre-operational environmental monitoring plan for the Device Assembly Facility at the Nevada Test Site

    Energy Technology Data Exchange (ETDEWEB)

    Ferate, F.D.

    1995-01-01

    Nuclear explosives operations have been and may continue to be an important component of the DOE mission at the NTS. This mission has been to conduct the nation`s nuclear testing program in a safe, secure, and efficient manner while assuring full compliance with state and federal regulations, and DOE order`s and directives. These operations have generally included assembly, disassembly or modification, staging, transportation, and tesbng of nuclear explosive devices. They may also include maintenance, repair, retrofit, and surveillance. The Device Assembly Facility (DAF) was constructed to provide a dedicated facility in which to prepare nuclear explosives assemblies for their intended disposition. This facility will provide for combined operations (replacing two separate facilities) and incorporates state-of-the-art safety and security features while minimizing the risks of environmental impacts. The facility has been completed but not yet operated, so the impacts to be considered will b e based on normal operations and not on the impacts of construction activities. The impacts will arise from nuclear explosives operations that require the handling of high explosives in combination with special nuclear materials. Wastes from operation of the earlier device assembly facilities have included grams of epoxies, pints of solvents, and small quantities of waste explosives. These are hazardous (includes radioactive) wastes and are disposed of in accordance with state and federal regulations. Assuming similar operations at the DAF, non-hazardous (includes non-radioactive) solid waste would be transported to a permitted landfill. Waste explosives would be sent to the Area 11 Explosive Ordnance Disposal Unit. Other hazardous waste would be sent to the Area 5 Radioactive Waste.Management Site for shipment or burial.

  14. Monitoring methanogenic population dynamics in a full-scale anaerobic digester to facilitate operational management.

    Science.gov (United States)

    Williams, Julie; Williams, Haydn; Dinsdale, Richard; Guwy, Alan; Esteves, Sandra

    2013-07-01

    Microbial populations in a full-scale anaerobic digester fed on food waste were monitored over an 18-month period using qPCR. The digester exhibited a highly dynamic environment in which methanogenic populations changed constantly in response to availability of substrates and inhibitors. The methanogenic population in the digester was dominated by Methanosaetaceae, suggesting that aceticlastic methanogenesis was the main route for the production of methane. Sudden losses (69%) in Methanosaetaceae were followed by a build-up of VFAs which were subsequently consumed when populations recovered. A build up of ammonium inhibited Methanosaetaceae and resulted in shifts from acetate to hydrogen utilization. Addition of trace elements and alkalinity when propionate levels were high stimulated microbial growth. Routine monitoring of microbial populations and VFAs provided valuable insights into the complex processes occurring within the digester and could be used to predict digester stability and facilitate digester optimization.

  15. Salient features, response and operation of Lead-Free Gulmarg Neutron Monitor

    Science.gov (United States)

    Mufti, S.; Chatterjee, S.; Ishtiaq, P. M.; Darzi, M. A.; Mir, T. A.; Shah, G. N.

    2016-03-01

    Lead-Free Gulmarg Neutron Monitor (LFGNM) provides continuous ground level intensity measurements of atmospheric secondary neutrons produced in interactions of primary cosmic rays with the Earth's constituent atmosphere. We report the LFGNM detector salient features and simulation of its energy response for 10-11 MeV to 104 MeV energy incident neutrons using the FLUKA Monte Carlo package. An empirical calibration of the LFGNM detector carried out with a Pu-Be neutron source for maximising its few MeV neutron counting sensitivity is also presented. As an illustration of its functionality a single representative transient solar modulation event recorded by LFGNM depicting Forbush decrease in integrated neutron data for which the geospace consequences are well known is also presented. Performance of LFGNM under actual observation conditions for effectively responding to transient solar modulation is seen to compare well with other world-wide conventional neutron monitors.

  16. Salient features, response and operation of Lead-Free Gulmarg Neutron Monitor

    Energy Technology Data Exchange (ETDEWEB)

    Mufti, S., E-mail: mufti.sabiuddin@gmail.com [Astrophysical Sciences Division, Nuclear Research Laboratory, Bhabha Atomic Research Centre, Srinagar - 190 006 (India); Chatterjee, S. [TLD Unit, Variable Energy Cyclotron Centre, Bhabha Atomic Research Centre, 1/AF-Bidhannagar, Kolkata - 700 064 (India); Ishtiaq, P.M.; Darzi, M.A.; Mir, T.A.; Shah, G.N. [Astrophysical Sciences Division, Nuclear Research Laboratory, Bhabha Atomic Research Centre, Srinagar - 190 006 (India)

    2016-03-21

    Lead-Free Gulmarg Neutron Monitor (LFGNM) provides continuous ground level intensity measurements of atmospheric secondary neutrons produced in interactions of primary cosmic rays with the Earth's constituent atmosphere. We report the LFGNM detector salient features and simulation of its energy response for 10{sup −11} MeV to 10{sup 4} MeV energy incident neutrons using the FLUKA Monte Carlo package. An empirical calibration of the LFGNM detector carried out with a Pu–Be neutron source for maximising its few MeV neutron counting sensitivity is also presented. As an illustration of its functionality a single representative transient solar modulation event recorded by LFGNM depicting Forbush decrease in integrated neutron data for which the geospace consequences are well known is also presented. Performance of LFGNM under actual observation conditions for effectively responding to transient solar modulation is seen to compare well with other world-wide conventional neutron monitors.

  17. The Revival of Environmental Monitoring within New Scientific and Operational Paradigms

    Directory of Open Access Journals (Sweden)

    Arturo Sánchez-Azofeifa

    2017-06-01

    Full Text Available The science of environmental monitoring is suffering from two major phenomena: exponential growth in the ability to obtain large amounts of data, and the way we communicate them. Today we are looking to develop methods to unify theoretical experiments with simulations taking into consideration the tera-bites of information that are being generated as a result of the development in wireless telecommunications, and then analyze them in real time and communicate them to relevant audiences relatively short after. In this sense, one of the most interesting emerging systems applied to environmental monitoring is what are called wireless sensor networks (WSN. Here they are presented, and some of their uses, advantages and challenges are explained.

  18. InfoSequia: the first operational remote sensing-based Drought Monitoring System of Spain

    Science.gov (United States)

    Contreras, Sergio; Hunink, Johannes E.

    2016-04-01

    We present a satellite-based Drought Monitoring System that provides weekly updates of maps and bulletins with vegetation drought indices over the Iberian Peninsula. The web portal InfoSequía (http://infosequia.es) aims to complement the current Spanish Drought Monitoring System which relies on a hydrological drought index computed at the basin level using data on river flows and water stored in reservoirs. Drought indices computed by InfoSequia are derived from satellite data provided by MODIS sensors (TERRA and AQUA satellites), and report the relative anomaly observed in the Normalized Difference Vegetation Index (NDVI), Land Surface Temperature (LST), and in an additive combination of both. Similar to the U.S. Drought Monitoring System by NOAA, the indices include the Vegetation Condition Index (VCI, relative NDVI anomaly), the Temperature Condition Index (TCI, relative LST anomaly) and the Vegetation Health Index (VHI, relative NDVI-LST anomaly). Relative anomalies are codified into four warning levels, and all of them are provided for short periods of time (8-day windows), or longer periods (e.g. 1 year) in order to capture the cumulative effects of droughts in the state variables. Additionally, InfoSequia quantifies the seasonal trajectories of the cumulative deviation of the observed NDVI in relation with the averaged seasonal trajectory observed over a reference period. Through the weekly bulletins, the Drought Monitoring System InfoSequia aims to provide practical information to stakeholders on the sensitivity and resilience of native ecosystems and rainfed agrosystems during drought periods. Also, the remote sensed indices can be used as drought impact indicator to evaluate the skill of seasonal agricultural drought forecasting systems. InfoSequia is partly funded by the Spanish Ministry of Economy and Competiveness through a Torres-Quevedo grant.

  19. National and Regional Scale Rice Crop Monitoring in Asia with the RIICE and PRISM Projects: From Research to Operation

    Science.gov (United States)

    Nelson, A.; Quicho, E. D.; Maunahan, A. A.; Setiyono, T. D.; Raviz, J. V.; Rala, A. B.; Laborte, A. G.; Holecz, F.; Collivignarelli, F.; Gatti, L.; Barbieri, M.; Mabalay, M. R. O.; De Dios, J. L.; Quilang, E. J. P.

    2015-12-01

    In recent years, remote sensing based mapping and monitoring of the rice crop have been demonstrated in many pilot studies and research sites - mainly in Asia - using both optical and SAR sensors and ground based observations. These efforts have been partly driven by the high demand for more timely, more detailed and more accurate information on the rice crop for applications in both public and private sector, such as food security policy, crop and land management, infrastructure investment and crop insurance. The basic premise being that better access to better information leads to eventual benefits for both producers and consumers through better investment and management at all levels. To realise these benefits means scaling up this work to national and regional levels. This presentation summarises the progress of two related projects in Asia: RIICE (Remote Sensing-based Information and Insurance in emerging Economies) and PRISM (Philippine Rice Information SysteM) that are making the transition from research to operation with the support of national governments and international donors. The presentation focuses on the technology, the partnerships, the achievements and the challenges in embedding both the capacity and the technology for remote sensing based monitoring of rice in countries in South and South East Asia. We highlight several aspects which are essential for a successful transition to a sustainable operational status and lessons learned in each country where the two projects have been operating.

  20. Shoulder pain management. The role of physical and rehabilitation medicine physicians. The European perspective based on the best evidence. A paper by the UEMS-PRM Section Professional Practice Committee.

    Science.gov (United States)

    Varela, E; Valero, R; Küçükdeveci, A A; Oral, A; Ilieva, E; Berteanu, M; Christodoulou, N

    2013-10-01

    One of the objectives of the Professional Practice Committee (PPC) of the Physical and Rehabilitation Medicine (PRM) Section of the Union of European Medical Specialists (UEMS) is the development of the field of competence of PRM physicians in Europe. To achieve this objective, UEMS PRM Section PPC has adopted a systematic action plan of preparing a series of papers describing the role of PRM physicians in a number of disabling health conditions, based on the evidence of effectiveness of the physical and rehabilitation medicine interventions. According to the PCC of the UEMS-PRM Section, the role of PRM physician in the management of shoulder pain (SP) has to be situated inside the general pain management field. SP is a common condition that can place limitations on the activity and restriction in social life participation of sufferers. A variety of shoulder problems, commonly including subacromial impingement, calcifying tendinitis, frozen shoulder, acromio-clavicular disturbances, gleno-humeral instability and gleno-humeral arthritis, can cause pain, and patients should be assessed and treated in order to relieve symptoms and reduce disability. This position paper describes the role of the PRM specialist in the management of such patients. Many assessment methods and treatment interventions are usually used in the management of patients with SP. Depending on the process, disability and patient characteristics, some intervention modalities have reported evidence in pain relief, movement and daily life activity (DLA) restoration, thus permiting a patient early recovery and social participation. Oral medications, local injections, physical therapy modalities and exercises are normally used for the management of SP. The PRM specialist should, always use this best medical evidence to decide how to efficiently and effectively reduce SP-related disability. An adequate therapeutic algorithm is also proposed in order to channelize the above mentioned evidence and reach

  1. Two-Year Operational Evaluation Of A Consumer Electronics-Based Data Acquisition System For Equipment Monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Van Hoy, Blake W. [ORNL; Phillips, Larry D. [ORNL; Wetherington Jr, G Randall [ORNL; Damiano, Brian [ORNL; Green, Craig [ORNL

    2017-04-01

    Oak Ridge National Laboratory (ORNL) has performed a two-year evaluation of the performance of an in-house developed consumer electronics-based data acquisition system (DAS). The main advantage of this approach compared to conventional instrumentation grade systems is cost; instrument grade data acquisition systems average costs range from $800 to $2,000 per channel compared to a range of $200 - $400 per channel for a consumer electronics-based system. The DAS is operated as a full-time in-situ vibration monitor. The resulting data stream is streamed over the ORNL network, at an aggregate rate of approximately 2 megabytes/s, to a Linux server. The server includes the capability to implement event-triggered data stores, as well as real-time files for the implementation of continuous display monitoring of the spectra. Detailed spectral analysis is performed post event. The DAS is installed on a large industrial chiller and cooling water pump associated with ORNL’s Titan supercomputer. These mechanical systems include rotating components that operate at fundamental frequencies within the range of 30 Hz to over 3 KHz. Evaluation of the DAS data over a two-year operating period leads to the conclusion that for many industrial processes this system could form the basis for a cost effective means of obtaining operating health data in real time from rotating machinery. The deployment has also shown that the DAS technology is reliable. Furthermore, because the cost of the DAS is low, the other significant advantage of this approach is that the DAS can be deployed in a dedicated manner and operated on a full-time basis.

  2. Operational availability improvement through online monitoring and advice for emergency diesel generator

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jong Beom; Kim, Han Gon; Kim, Byong Sup [Korea Electric Power Research Institute, Taejon (Korea, Republic of); Golay, M.; Kang, C. W.; Sui, Y. [Massachusetts Institute of Technology, Massachusetts (United States)

    1998-12-31

    This research broadens the prime concern of nuclear power plant operations from safe performance to both economic and safe performance. First, emergency diesel generator is identified as one of main contributors for the lost plant availability through the review of plant forced outage records. The framework of an integrated architecture of performing modern on-line condition for operational availability improvement is configured in this work. For the development of the comprehensive sensor networks for complex target systems, and integrated methodology incorporating a structural hierarchy, a functional hierarchy, and a fault-symptom matrix is formulated. The second part of our research is development of intelligent diagnosis and maintenance advisory system, which employs Bayesian Belief Networks (BBNs) as a high level reasoning tool for incorporating inherent uncertainty for use in probabilistic inference. Our prototype diagnosis algorithms are represented explicitly through topological symbols and links between them in a causal direction. As new evidence from sensor network developed is entered into the model especially, our advisory system provides operational advice concerning both availability and safety, so that the operator is able to determine the likely failure modes, diagnose the system state, locate root causes, and take the most advantageous action. Thereby, this advice improves operational availability. 6 refs., 7 figs., 1 tab. (Author)

  3. New oil condition monitoring system, Wearsens® enables continuous, online detection of critical operating conditions and wear damage

    Directory of Open Access Journals (Sweden)

    Manfred Mauntz

    2015-12-01

    Full Text Available A new oil sensor system is presented for the continuous, online measurement of the wear in turbines, industrial gears, generators, hydraulic systems and transformers. Detection of change is much earlier than existing technologies such as particle counting, vibration measurement or recording temperature. Thus targeted, corrective procedures and/or maintenance can be carried out before actual damage occurs. Efficient machine utilization, accurately timed preventive maintenance, increased service life and a reduction of downtime can all be achieved. The presented sensor system effectively controls the proper operation conditions of bearings and cogwheels in gears. The online diagnostics system measures components of the specific complex impedance of oils. For instance, metal abrasion due to wear debris, broken oil molecules, forming acids or oil soaps, result in an increase of the electrical conductivity, which directly correlates with the degree of contamination of the oil. For additivated lubricants, the stage of degradation of the additives can also be derived from changes in the dielectric constant. The determination of impurities or reduction in the quality of the oil and the quasi continuous evaluation of wear and chemical aging follow the holistic approach of a real-time monitoring of an alteration in the condition of the oil-machine system. Once the oil condition monitoring sensors are installed on the wind turbine, industrial gearbox and test stands, the measuring data can be displayed and evaluated elsewhere. The signals are transmitted to a web-based condition monitoring system via LAN, WLAN or serial interfaces of the sensor unit. Monitoring of the damage mechanisms during proper operation below the tolerance limits of the components enables specific preventive maintenance independent of rigid inspection intervals.

  4. Bunch arrival time monitors; Concepts towards improving the sensitivity for low charge operation for FLASH II and XFEL

    Energy Technology Data Exchange (ETDEWEB)

    Penirschke, Andreas; Angelovski, Aleksandar; Jakoby, Rolf [TU Darmstadt, Institut fuer Mikrowellentechnik und Photonik, Merckstr. 25, 64283 Darmstadt (Germany); Sydlo, Cezary; Bousonville, Michael; Czwalinna, Marie Kristin; Schlarb, Holger [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Kuhl, Alexander [University of Hamburg, Physics Department, Accelerator Physics Group (Germany); Weiland, Thomas [Technische Univ. Darmstadt (Germany). Inst. fuer Theorie Elektromagnetischer Felder

    2013-07-01

    High gain Free-Electron Lasers can generate ultra short X-ray pulses in the femtosecond range. For a stable operation of the FEL, the precise knowledge of the bunch arrival time is crucial. A novel high bandwidth Bunch Arrival time Monitor was recently installed at FLASH to allow a low charge operation mode with a sub-10 fs resolution for bunch charges of 20 pC or more. The BAM is equipped with cone shaped pickups for the precise measurement of both, the high and low bunch charge operation mode. For the extension of FLASH facility to FLASH II new pickups for the high bandwidth BAMs need to be developed. The new BAM needs to maximize the voltage level of the beam induced signal for low charge operation mode in order to provide sufficient signal strength for the subsequent electronics. In this talk, we present concepts to improve the signal strength at the electro-optic modulators for low charge operation at FLASH II and XFEL.

  5. Dengue NS1 and prM antibodies increase the sensitivity of acute dengue diagnosis test and differentiate from Japanese encephalitis infection.

    Science.gov (United States)

    Gowri Sankar, S; Balaji, T; Venkatasubramani, K; Thenmozhi, V; Dhananjeyan, K J; Paramasivan, R; Tyagi, B K; John Vennison, S

    2014-05-01

    Accurate and early diagnosis of dengue infection is essential for dengue case management. In outbreak conditions, it is essential to include two different tests to diagnose dengue and the choice depends on the number of days after the onset of illness in which the sample is collected. During the laboratory diagnosis of dengue in late acute and convalescent phase by MAC-ELISA, it is necessary to rule out possible cross reactions of closely related flavivirus, such as Japanese encephalitis virus which is commonly co-circulating. In the present investigation, the usefulness of dengue virus NS1 and prM antibodies in diagnosing and differentiating dengue from Japanese encephalitis infection was assessed using samples collected during out-breaks. It was shown here that, detection of antibodies against dengue NS1 and prM proteins increases the sensitivity of dengue diagnosis until 15days. Moreover, detection of antibodies against both proteins was able to differentiate dengue from Japanese encephalitis infection.

  6. Performance of a GM tube based environmental dose rate monitor operating in the Time-To-Count mode

    Energy Technology Data Exchange (ETDEWEB)

    Zickefoose, J.; Kulkarni, T.; Martinson, T.; Phillips, K.; Voelker, M. [Canberra Industries Inc. (United States)

    2015-07-01

    The events at the Fukushima Daiichi power plant in the aftermath of a natural disaster underline the importance of a large array of networked environmental monitors to cover areas around nuclear power plants. These monitors should meet a few basic criteria: have a uniform response over a wide range of gamma energies, have a uniform response over a wide range of incident angles, and have a large dynamic range. Many of these criteria are met if the probe is qualified to the international standard IEC 60532 (Radiation protection instrumentation - Installed dose rate meters, warning assemblies and monitors - X and gamma radiation of energy between 50 keV and 7 MeV), which specifically deals with energy response, angle of incidence, dynamic range, response time, and a number of environmental characteristics. EcoGamma is a dual GM tube environmental gamma radiation monitor designed specifically to meet the requirements of IEC 60532 and operate in the most extreme conditions. EcoGamma utilizes two energy compensated GM tubes operating with a Time-To-Count (TTC) collection algorithm. The TTC algorithm extends the lifetime and range of a GM tube significantly and allows the dual GM tube probe to achieve linearity over approximately 10 decades of gamma dose rate (from the Sv/hr range to 100 Sv/hr). In the TTC mode of operation, the GM tube is not maintained in a biased condition continuously. This is different from a traditional counting system where the GM tube is held at a constant bias continuously and the total number of strikes that the tube registers are counted. The traditional approach allows for good sensitivity, but does not lend itself to a long lifetime of the tube and is susceptible to linearity issues at high count rates. TTC on the other hand only biases the tube for short periods of time and in effect measures the time between events, which is statistically representative of the total strike rate. Since the tube is not continually biased, the life of the tube

  7. Application of Industry Automation Control in YOKOGAWA PRM System%横河PRM系统在工业自控上的应用

    Institute of Scientific and Technical Information of China (English)

    李莉

    2011-01-01

    目前工厂资源管理系统PRM (Plant Resource Manager)逐步广泛应用于各工业控制领域,PRM实现资产优化管理,为客户的价值链增值,可以提供结合设备总体信息的自动控制解决方案,并且可以优化设备的整个生命周期.

  8. Efficient assembly and secretion of recombinant subviral particles of the four dengue serotypes using native prM and E proteins.

    Directory of Open Access Journals (Sweden)

    Pei-Gang Wang

    Full Text Available BACKGROUND: Flavivirus infected cells produce infectious virions and subviral particles, both of which are formed by the assembly of prM and E envelope proteins and are believed to undergo the same maturation process. Dengue recombinant subviral particles have been produced in cell cultures with either modified or chimeric proteins but not using the native forms of prM and E. METHODOLOGY/PRINCIPAL FINDINGS: We have used a codon optimization strategy to obtain an efficient expression of native viral proteins and production of recombinant subviral particles (RSPs for all four dengue virus (DV serotypes. A stable HeLa cell line expressing DV1 prME was established (HeLa-prME and RSPs were analyzed by immunofluorescence and transmission electron microscopy. We found that E protein is mainly present in the endoplasmic reticulum (ER where assembly of RSPs could be observed. Biochemical characterization of DV1 RSPs secretion revealed both prM protein cleavage and homodimerization of E proteins before their release into the supernatant, indicating that RSPs undergo a similar maturation process as dengue virus. Pulse chase experiment showed that 8 hours are required for the secretion of DV1 RSPs. We have used HeLa-prME to develop a semi-quantitative assay and screened a human siRNA library targeting genes involved in membrane trafficking. Knockdown of 23 genes resulted in a significant reduction in DV RSP secretion, whereas for 22 others we observed an increase of RSP levels in cell supernatant. CONCLUSIONS/SIGNIFICANCE: Our data describe the efficient production of RSPs containing native prM and E envelope proteins for all dengue serotypes. Dengue RSPs and corresponding producing cell lines are safe and novel tools that can be used in the study of viral egress as well as in the development of vaccine and drugs against dengue virus.

  9. Multifunctional ultrasonic sensor for on-line tool condition monitoring in turning operations

    Energy Technology Data Exchange (ETDEWEB)

    Nayfeh, T.H.; Abu-Zahra, N.H. [Cleveland State Univ., OH (United States). Industrial Engineering Dept.

    1998-03-01

    Machining operations in automated manufacturing centers are, in general, under-performing by 20--80 percent. Optimizing these machining operations requires on-line knowledge of the cutting tool`s condition and the process state. Currently, this information is either not reliable or not available in a timely manner. This in part is due to the lack of suitable sensors which are able to measure on-line directly and accurately one or more of the relevant tool and process variables. A direct, active, ultrasonic method for on-line sensing of the tool condition and the process state in turning operations was developed in this work. Sensing is achieved by using an ultrasonic transducer operating at 10 MHz in a pulse-echo mode to send pulses through the cutting tool. The amplitude and propagation time of the reflected pulses are modulated by the tool nose, flank, temperature, and by the material in contact with the tools. This method has the potential to measure on-line several relevant process and cutting tool parameters directly and accurately through the use of a single sensor. These parameters are tool-workpiece contact, tool gradual wear, tool chipping and tool chatter.

  10. 40 CFR 63.127 - Transfer operations provisions-monitoring requirements.

    Science.gov (United States)

    2010-07-01

    ... Chemical Manufacturing Industry for Process Vents, Storage Vessels, Transfer Operations, and Wastewater... to the atmosphere; or (2) Secure the by-pass line valve in the closed position with a car-seal or a... vent stream is not diverted through the by-pass line. (ii) If a car-seal has been broken or a valve...

  11. 40 CFR 63.7331 - What are the installation, operation, and maintenance requirements for my monitors?

    Science.gov (United States)

    2010-07-01

    ... pushing emissions, you must install, operate, and maintain CPMS to measure and record the pressure drop... the pressure drop across each multicyclone during each push according to the requirements in... a manner consistent with the guidance document, “Fabric Filter Bag Leak Detection Guidance”...

  12. The Participation of the Danish Navy in Operation Maritime Monitor / Sharp Guard 1993-1996

    DEFF Research Database (Denmark)

    Nørby, Søren

    2015-01-01

    When Danish corvette Olfert Fischer joined the UN operation against Iraq in 1990-1991, it was seen as the most significant sign of the changing security situation which Denmark and the Navy were facing following the fall of the Berlin Wall in 1989 and the subsequent collapse of the Warsaw Pact. M...

  13. Design considerations for remotely operated welding in space: Task definition and visual weld monitoring experiment

    Science.gov (United States)

    Reynerson, Charles M.

    1993-05-01

    This thesis explores the concept of welding in a space environment with the use of automation. Since the amount of time astronauts can work outside a spacecraft is limited, future construction and repair tasks will likely be assisted by automation. It is also likely that remote space welding will be needed for the construction of large-scale space structures in earth orbit as well as for lunar and Martian ground-based structures. Due to the complex nature of the tasks to be accomplished, the equipment will probably not be fully autonomous but instead supervised by a human operator. The welding fabrication problem in space is examined in a broad sense including some of the considerations for designing a human supervisory remote welding system. The history of space welding processes is examined, as well as current research in the field. A task definition and functional analysis is provided to assist future designers in outlining typical operational sequences for such a remote welding system. Such analysis is important when deciding whether the human operator should perform certain tasks or if the operator should supervise the automated system while it performs the tasks.

  14. 40 CFR 63.9306 - What are my continuous parameter monitoring system (CPMS) installation, operation, and...

    Science.gov (United States)

    2010-07-01

    ... provides a representative temperature. (ii) Use a temperature sensor with a measurement sensitivity of 4... temperature chart recorder is used, it must have a measurement sensitivity in the minor division of at least... period of the emission capture system and add-on control device operation. (3) You must record...

  15. Cochlear implant electrode array insertion monitoring with intra-operative 3D rotational X-ray

    NARCIS (Netherlands)

    Carelsen, B; Grolman, W; Tange, R; Streekstra, G J; van Kemenade, P; Jansen, R J; Freling, N J M; White, M; Maat, B; Fokkens, W J

    2007-01-01

    During cochlear implantation surgery, we use a mobile C-arm with 3D functionality to acquire per-operative 3D X-ray images. Scanning the multielectrode array is performed once before removal of the stylet and once after full insertion. When dissatisfied with the position of the multielectrode a repo

  16. Monitoring operating temperature and supply voltage in achieving high system dependability

    NARCIS (Netherlands)

    Khan, M.A.; Kerkhoff, Hans G.

    2013-01-01

    System dependability being a set of number of attributes, of which the important reliability, heavily depends on operating temperature and supply voltage. Any change beyond the designed specifications may change the system performance and could result in system reliability and hence dependability

  17. Monitoring operating temperature and supply voltage in achieving high system dependability

    NARCIS (Netherlands)

    Khan, M.A.; Kerkhoff, Hans G.

    2013-01-01

    System dependability being a set of number of attributes, of which the important reliability, heavily depends on operating temperature and supply voltage. Any change beyond the designed specifications may change the system performance and could result in system reliability and hence dependability pr

  18. Monitoring operating temperature and supply voltage in achieving high system dependability

    NARCIS (Netherlands)

    Khan, Muhammad Aamir; Kerkhoff, Hans G.

    2013-01-01

    System dependability being a set of number of attributes, of which the important reliability, heavily depends on operating temperature and supply voltage. Any change beyond the designed specifications may change the system performance and could result in system reliability and hence dependability pr

  19. Using Smart Meters Data for Energy Management Operations and Power Quality Monitoring in a Microgrid

    DEFF Research Database (Denmark)

    Palacios-Garcia, Emilio J.; Diaz, Enrique Rodriguez; Anvari-Moghaddam, Amjad

    2017-01-01

    Smart metering devices have become an essential part in the development of the current electrical network toward the paradigm of Smart Grid. These meters present in most of the cases, functionalities whose analysis capabilities go further beyond the basic automated meter readings for billing...... of a commercial advanced metering infrastructure (AMI) in the context of a smart building with an energy management system (EMS). Furthermore, power quality monitoring based on this AMI is explained. All the details regarding the implementation in a laboratory scale application, as well as the obtained results...

  20. Spectroscopic and magnetic properties of the metastable states in the coordination network [{Co(prm)2}2{Co(H2O)2}{W(CN)8}2]·4H2O (prm = pyrimidine).

    Science.gov (United States)

    Le Bris, Rémy; Tsunobuchi, Yoshihide; Mathonière, Corine; Tokoro, Hiroko; Ohkoshi, Shin-ichi; Ould-Moussa, Nawel; Molnar, Gabor; Bousseksou, Azzedine; Létard, Jean-François

    2012-03-05

    The study of the metastable states, obtained by thermal quenching or by light irradiation in the [{Co(prm)(2)}(2){Co(H(2)O)(2)}{W(CN)(8)}(2)]·4H(2)O complex, is reported using powder X-ray diffraction, Raman spectroscopy, optical reflectivity, and magnetic measurements. This compound is characterized by a electron-transfer (ET) phase transition occurring between a high-temperature phase (HT phase) formed by paramagnetic Co(II)-W(V) units and a low-temperature phase (LT phase) formed by diamagnetic Co(III)-W(IV) units. Metastable phases can be induced at low temperature either by thermal quenching rapidly cooling phase named RC or by irradiation photo-induced phase named PI similar to the well-known Light-Induced Excited Spin State Trapping effect. The relaxation dynamics of the metastable phases have been studied and revealed some differences between the RC and PI phases. The sigmoidal shape of the relaxation curves in the RC phase is in agreement with the cooperative nature of the process. Thermodynamic parameters that govern the relaxation have been determined and used to reproduce the experimental Thermal-Induced Excited Spin State Trapping curve.

  1. Mini-Mega-TORTORA wide-field monitoring system with sub-second temporal resolution: first year of operation

    Science.gov (United States)

    Karpov, S.; Beskin, G.; Biryukov, A.; Bondar, S.; Ivanov, E.; Katkova, E.; Perkov, A.; Sasyuk, V.

    2016-12-01

    Here we present the summary of first years of operation and the first results of a novel 9-channel wide-field optical monitoring system with sub-second temporal resolution, Mini-Mega-TORTORA (MMT-9), which is in operation now at Special Astrophysical Observatory on Russian Caucasus. The system is able to observe the sky simultaneously in either wide (˜900 square degrees) or narrow (˜100 square degrees) fields of view, either in clear light or with any combination of color (Johnson-Cousins B, V or R) and polarimetric filters installed, with exposure times ranging from 0.1 s to hundreds of seconds. The real-time system data analysis pipeline performs automatic detection of rapid transient events, both near-Earth and extragalactic. The objects routinely detected by MMT include faint meteors and artificial satellites. The pipeline for a longer time scales variability analysis is still in development.

  2. Operational strategies, monitoring and control of heterologous protein production in the methylotrophic yeast Pichia pastoris under different promoters: A review

    Directory of Open Access Journals (Sweden)

    Valero Francisco

    2006-04-01

    Full Text Available Abstract The methylotrophic yeast Pichia pastoris has been widely reported as a suitable expression system for heterologous protein production. The use of different phenotypes under PAOX promoter, other alternative promoters, culture medium, and operational strategies with the objective to maximize either yield or productivity of the heterologous protein, but also to obtain a repetitive product batch to batch to get a robust process for the final industrial application have been reported. Medium composition, kinetics growth, fermentation operational strategies from fed-batch to continuous cultures using different phenotypes with the most common PAOX promoter and other novel promoters (GAP, FLD, ICL, the use of mixed substrates, on-line monitoring of the key fermentation parameters (methanol and control algorithms applied to the bioprocess are reviewed and discussed in detail.

  3. Generation and preclinical evaluation of a DENV-1/2 prM+E chimeric live attenuated vaccine candidate with enhanced prM cleavage.

    Science.gov (United States)

    Keelapang, Poonsook; Nitatpattana, Narong; Suphatrakul, Amporn; Punyahathaikul, Surat; Sriburi, Rungtawan; Pulmanausahakul, Rojjanaporn; Pichyangkul, Sathit; Malasit, Prida; Yoksan, Sutee; Sittisombut, Nopporn

    2013-10-17

    In the absence of a vaccine or sustainable vector control measures, illnesses caused by dengue virus infection remain an important public health problem in many tropical countries. During the export of dengue virus particles, furin-mediated cleavage of the prM envelope protein is usually incomplete, thus generating a mixture of immature, partially mature and mature extracellular particles. Variations in the arrangement and conformation of the envelope proteins among these particles may be associated with their different roles in shaping the antibody response. In an attempt to improve upon live, attenuated dengue vaccine approaches, a mutant chimeric virus, with enhanced prM cleavage, was generated by introducing a cleavage-enhancing substitution into a chimeric DENV-1/2 virus genome, encoding the prM+E sequence of a recent DENV-1 isolate under an attenuated DENV-2 genetic background. A modest increase in virus specific infectivity observed in the mutant chimeric virus affected neither the attenuation phenotype, when assessed in the suckling mouse neurovirulence model, nor multiplication in mosquitoes. The two chimeric viruses induced similar levels of anti-DENV-1 neutralizing antibody response in mice and rhesus macaques, but more efficient control of viremia during viral challenge was observed in macaques immunized with the mutant chimeric virus. These results indicate that the DENV-1/2 chimeric virus, with enhanced prM cleavage, could be useful as an alternative live, attenuated vaccine candidate for further tests in humans.

  4. Monitoring the dynamics of an invasive emergent macrophyte community using operational remote sensing data

    Science.gov (United States)

    Albright, T.P.; Ode, D.J.

    2011-01-01

    Potamogeton crispus L. (curly pondweed) is a cosmopolitan aquatic macrophyte considered invasive in North America and elsewhere. Its range is expanding and, on individual water bodies, its coverage can be dynamic both within and among years. In this study, we evaluate the use of free and low-cost satellite remote sensing data to monitor a problematic emergent macrophyte community dominated by P. crispus. Between 2000 and 2006, we acquired eight satellite images of 24,000-ha Lake Sharpe, South Dakota (USA). During one of the dates for which satellite imagery was acquired, we sampled the lake for P. crispus and other emergent macrophytes using GPS and photography for documentation. We used cluster analysis to assist in classification of the satellite imagery and independently validated results using the field data. Resulting estimates of emergent macrophyte coverage ranged from less than 20 ha in 2002 to 245 ha in 2004. Accuracy assessment indicated 82% of image pixels were correctly classified, with errors being primarily due to failure to identify emergent macrophytes. These results emphasize the dynamic nature of P. crispus-dominated macrophyte communities and show how they can be effectively monitored over large areas using low-cost remote sensing imagery. While results may vary in other systems depending on water quality and local flora, such an approach could be applied elsewhere and for a variety of macrophyte communities. ?? Springer Science+Business Media B.V. 2010.

  5. ATLAS Trigger Monitoring and Operation in Proton Proton Collisions at 900 GeV

    CERN Document Server

    zur Nedden, M; The ATLAS collaboration

    2010-01-01

    The trigger of the ATLAS-experiment is build as a three level system. The first level is realized in hardware while the higher levels (HLT) are pure software implemented triggers based on large PC farms. According to the LHC bunch crossing frequency of 40 MHz and the expectation of up to 23 interactions per bunch crossing at design luminosity, the trigger system must be able to deal with an input rate of 1 GHz whereas the maximum storage rate is 200 Hz. This complex data acquisition and trigger system requires a reliable and redundant diagnostic and monitoring system. This is inevitable for a successful commissioning and stable running of the whole experiment. The main aspects of trigger monitoring are the rate measurements at each step of the trigger decision at each level, the determination of the quality of the physics objects candidates to be selected at trigger level (as candidates for electrons, muons, taus, gammas, jets, b-jets and missing energy) and the supervision of the system's behavior during the...

  6. Human Factors Engineering (HFE) insights for advanced reactors based upon operating experience

    Energy Technology Data Exchange (ETDEWEB)

    Higgins, J.; Nasta, K.

    1997-01-01

    The NRC Human Factors Engineering Program Review Model (HFE PRM, NUREG-0711) was developed to support a design process review for advanced reactor design certification under 10CFR52. The HFE PRM defines ten fundamental elements of a human factors engineering program. An Operating Experience Review (OER) is one of these elements. The main purpose of an OER is to identify potential safety issues from operating plant experience and ensure that they are addressed in a new design. Broad-based experience reviews have typically been performed in the past by reactor designers. For the HFE PRM the intent is to have a more focussed OER that concentrates on HFE issues or experience that would be relevant to the human-system interface (HSI) design process for new advanced reactors. This document provides a detailed list of HFE-relevant operating experience pertinent to the HSI design process for advanced nuclear power plants. This document is intended to be used by NRC reviewers as part of the HFE PRM review process in determining the completeness of an OER performed by an applicant for advanced reactor design certification. 49 refs.

  7. Federated data bases for the development of an operational monitoring and forecasting system of the ocean: the THREDDS Dataset Merger

    Directory of Open Access Journals (Sweden)

    S. Nativi

    2006-01-01

    Full Text Available During the last decade, operational monitoring and forecasting systems have been developed in all the European seas. The exchange of data and products and the development of services for a wide community of users pose some fundamental issues, whose solution has become a priority in integrated and GMES referring projects, such as the MERSEA European project. These projects aim to develop a European system for operational monitoring and forecasting on global and regional scales of ocean physics, bio-chemistry and ecosystems. GMES system and its operational projects need to federate resources and expertise coming from diverse organizations working on different Earth Sciences fields (e.g. satellite data processing, in situ observing systems, data management, ocean and ecosystem modeling, etc.. Therefore, it is required a Marine Information Management (MIM system capable of facilitating the regular real-time exchange of high quality information, data and products. Moreover, MIM system must provide appropriate information for a wide range of external users both in real-time and delayed mode. In this paper an architecture based on the OPeNDAP/THREDDS technology is proposed as a solution for these operational systems. In this context, a catalog merging solution is introduced for the MIM system, which results in the design and development of the THREDDS Dataset Merger (TDM: a set of services meant to merge THREDDS Dataset Inventory Catalogs, so to achieve a unique catalog service for a whole database federation. TDM service merges distributed and autonomous THREDDS catalogs in order to work out a virtual merged catalog. The TDM service was extended in order to provide automatic catalogs synchronization. This service allows extending the pull-based TDM paradigm to support push-based applications. Some security issues are also considered.

  8. Quantum logical operations for spin 3/2 quadrupolar nuclei monitored by quantum state tomography.

    Science.gov (United States)

    Bonk, F A; deAzevedo, E R; Sarthour, R S; Bulnes, J D; Freitas, J C C; Guimarães, A P; Oliveira, I S; Bonagamba, T J

    2005-08-01

    This article presents the realization of many self-reversible quantum logic gates using two-qubit quadrupolar spin 3/2 systems. Such operations are theoretically described using propagation matrices for the RF pulses that include the effect of the quadrupolar evolution during the pulses. Experimental demonstrations are performed using a generalized form of the recently developed method for quantum state tomography in spin 3/2 systems. By doing so, the possibility of controlling relative phases of superimposed pseudo-pure states is demonstrated. In addition, many aspects of the effect of the quadrupolar evolution, occurring during the RF pulses, on the quantum operations performance are discussed. Most of the procedures presented can be easily adapted to describe selective pulses of higher spin systems (>3/2) and for spin 1/2 under J couplings.

  9. Increasing the efficiency and lifetime extension of turbine condensers by means of monitoring its condition and operation; Leistungssteigerung und Lebensdauerverlaengerung von Turbinenkondensatoren durch Zustands- und Betriebsueberwachung

    Energy Technology Data Exchange (ETDEWEB)

    Czolkoss, Wolfgang [Taprogge GmbH, Wetter (Germany). Abt. Anwendungstechnik

    2010-07-01

    Loss in capacity and operational availability in steam power plants is often caused by adverse conditions in turbine condensers. Therefore, monitoring the condition and overall operation of the turbine condenser is an important part of maintaining an efficiently operating power station and preventing costly tube replacements. The operation of the tube cleaning system is of particular importance. Reference on monitoring tube cleaning as well as on the detection and elimination of malfunctions are given in order to detect fouling and corrosion problems in due time and to launch remedial measures. (orig.)

  10. Bus Operation Monitoring Oriented Public Transit Travel Index System and Calculation Models

    Directory of Open Access Journals (Sweden)

    Jiancheng Weng

    2013-01-01

    Full Text Available This study proposed a two-dimensional index system which is concerned essentially with urban travel based on travel modes and user satisfaction. First, the public transit was taken as an example to describe the index system establishing process. In consideration of convenience, rapid, reliability, comfort, and safety, a bus service evaluation index system was established. The indicators include the N-minute coverage of bus stops, average travel speed, and fluctuation of travel time between stops and bus load factor which could intuitively describe the characteristics of public transport selected to calculate bus travel indexes. Then, combined with the basic indicators, the calculation models of Convenience Index (CI, Rapid Index (RI, Reliability Index (RBI, and Comfort Index (CTI were established based on the multisource data of public transit including the real-time bus GPS data and passenger IC card data. Finally, a case study of Beijing bus operation evaluation and analysis was conducted by taking real bus operation data including GPS data and passenger transaction recorder (IC card data. The results showed that the operation condition of the public transit was well reflected and scientifically classified by the bus travel index models.

  11. Towards an Operational Vegetation Health Monitoring System for the Northern Great Plains

    Science.gov (United States)

    Aloysius, N.; Kim, H. J.

    2007-12-01

    Farmers and Rangers in the Northern Great Plains (NGP) of the United States had been devastated by the extremely dry weather conditions in the summer of 2006. The entire state of North Dakota was declared a primary agricultural disaster area in September, 2006 by the US Department of Agriculture. Emergency grazing on CRP lands was extended in several NGP states. On the contrary, the summer of 2005 had been exceptionally wet in certain parts of NGP which ruined crops. The occurrences of these weather extremes severely affect the natural resource based enterprises like farming and ranching, the effects of which ripple through the economies of several states in the region. In order to monitor and assess the impacts of these extreme events and to take mitigation strategies, variety of physical and environmental conditions have to be taken into consideration. Remote sensing based vegetation indices such as normalized difference vegetation index (NDVI) and enhanced vegetation index (EVI), climate information and drought indices are employed to assess the growth of vegetation and its vigor, both spatially and temporally. A 25-year history of NDVI and seven-year history of EVI data were used to develop a near real-time vegetation growth monitoring system for the five Northern Great Plains states (ID, MT, ND, SD and WY). The EVI and EVI anomaly, computed based on 2000-2005 averages, are updated twice monthly for the growing season, April through September. In addition, precipitation anomalies based on a 30-year average and Palmer Z-index (a short term moisture availability index) are also updated monthly for the 45 climate divisions within the NGP states. The presentation will highlight how the near real-time monitoring of the combination of vegetation and climate parameters can help to identify the temporal and spatial patterns of vegetation dynamics at different spatial (from individual farms, climate divisions to states and, even, the whole NGP region) and temporal

  12. Overview of condition monitoring and operation control of electric power conversion systems in direct-drive wind turbines under faults

    Science.gov (United States)

    Huang, Shoudao; Wu, Xuan; Liu, Xiao; Gao, Jian; He, Yunze

    2017-09-01

    Electric power conversion system (EPCS), which consists of a generator and power converter, is one of the most important subsystems in a direct-drive wind turbine (DD-WT). However, this component accounts for the most failures (approximately 60% of the total number) in the entire DD-WT system according to statistical data. To improve the reliability of EPCSs and reduce the operation and maintenance cost of DD-WTs, numerous researchers have studied condition monitoring (CM) and fault diagnostics (FD). Numerous CM and FD techniques, which have respective advantages and disadvantages, have emerged. This paper provides an overview of the CM, FD, and operation control of EPCSs in DD-WTs under faults. After introducing the functional principle and structure of EPCS, this survey discusses the common failures in wind generators and power converters; briefly reviewed CM and FD methods and operation control of these generators and power converters under faults; and discussed the grid voltage faults related to EPCSs in DD-WTs. These theories and their related technical concepts are systematically discussed. Finally, predicted development trends are presented. The paper provides a valuable reference for developing service quality evaluation methods and fault operation control systems to achieve high-performance and high-intelligence DD-WTs.

  13. Operational challenges for astronomical instrumentation in Antarctica: results from five years of environmental monitoring of AMICA at Dome C

    Science.gov (United States)

    Dolci, Mauro; Valentini, Angelo; Tavagnacco, Daniele; Di Cianno, Amico; Straniero, Oscar

    2016-08-01

    The Antarctic Plateau is one of the best observing sites on Earth, especially for infrared astronomy. The extremely low temperatures (down to -80°C), the low pressure (around 650 mbar) and the very dry atmosphere (PWV less than 1 mm) allow for a very clear and dark sky, as well as for a very low instrumental background. These unique properties, however, make it also very difficult to install and operate astronomical instrumentation. AMICA (Antarctic Multiband Infrared CAmera) is an instrument especially designed for Antarctic operation, whose installation at Dome C has been completed in 2013. Since then it has been continuously working over the last five years, monitoring and controlling in particular the environmental and operating conditions through a dedicated application, its Environmental Control System (ECS). The recorded behavior of AMICA highlighted a set of peculiar aspects of the site that are hard to consider a priori. Although mechanical and electronic COTS components can reliably work in thermally insulated and controlled boxes, simple insulation causes their overheating because of the air dryness and rarefaction which make the heat transfer extremely inefficient. Heat removal is also a real problem when managing heavy-duty devices like cryocoolers, whose excess power removal needs to be fast and efficient. Finally, the lack of an electrical ground generates a wide variety of transient electrical and electromagnetic phenomena which often make electronic instrumentation very unstable. A list of new recommendations is therefore presented, as a guideline for future astronomical instruments operating in Antarctica.

  14. Application of Novel Exploration and Monitoring Strategies for Sustainable Managed Aquifer Recharge Operation

    Science.gov (United States)

    Vienken, T.; Werban, U.; Cisotto, A.; Rossetto, R.; Dietrich, P.

    2015-12-01

    Water scarcity and drought have led to a strong decline of water availability in many semiarid countries with resulting ecological and economic impacts. Managed aquifer recharge (MAR), e.g. river bank infiltration or storm water infiltration basins and trenches, represents a promising technique to replenish water resources, and in combination with awareness raising, is an important step towards sustainable water management. However, choice of type and positioning large scale MAR infrastructure is challenging as it requires a detailed understanding of the subsurface. Furthermore, MAR site maintenance can be time intensive and costly as effects, such as bio clogging or colmation can lead to a strong decrease in infiltration capacity. In our work we will show examples of successful implementation of novel strategies of MAR site characterization and monitoring on different scales.

  15. Spectral imaging applications: Remote sensing, environmental monitoring, medicine, military operations, factory automation and manufacturing

    Energy Technology Data Exchange (ETDEWEB)

    Gat, N.; Subramanian, S. [Opto-Knowledge Systems, Inc. (United States); Barhen, J. [Oak Ridge National Lab., TN (United States); Toomarian, N. [Jet Propulsion Lab., Pasadena, CA (United States)

    1996-12-31

    This paper reviews the activities at OKSI related to imaging spectroscopy presenting current and future applications of the technology. The authors discuss the development of several systems including hardware, signal processing, data classification algorithms and benchmarking techniques to determine algorithm performance. Signal processing for each application is tailored by incorporating the phenomenology appropriate to the process, into the algorithms. Pixel signatures are classified using techniques such as principal component analyses, generalized eigenvalue analysis and novel very fast neural network methods. The major hyperspectral imaging systems developed at OKSI include the Intelligent Missile Seeker (IMS) demonstration project for real-time target/decoy discrimination, and the Thermal InfraRed Imaging Spectrometer (TIRIS) for detection and tracking of toxic plumes and gases. In addition, systems for applications in medical photodiagnosis, manufacturing technology, and for crop monitoring are also under development.

  16. Spectral imaging applications: Remote sensing, environmental monitoring, medicine, military operations, factory automation and manufacturing

    Science.gov (United States)

    Gat, N.; Subramanian, S.; Barhen, J.; Toomarian, N.

    1996-01-01

    This paper reviews the activities at OKSI related to imaging spectroscopy presenting current and future applications of the technology. The authors discuss the development of several systems including hardware, signal processing, data classification algorithms and benchmarking techniques to determine algorithm performance. Signal processing for each application is tailored by incorporating the phenomenology appropriate to the process, into the algorithms. Pixel signatures are classified using techniques such as principal component analyses, generalized eigenvalue analysis and novel very fast neural network methods. The major hyperspectral imaging systems developed at OKSI include the Intelligent Missile Seeker (IMS) demonstration project for real-time target/decoy discrimination, and the Thermal InfraRed Imaging Spectrometer (TIRIS) for detection and tracking of toxic plumes and gases. In addition, systems for applications in medical photodiagnosis, manufacturing technology, and for crop monitoring are also under development.

  17. Crucible and coil monitoring during melting operation in induction crucible furnaces; Tiegel- und Spulenueberwachung beim Schmelzbetrieb von Induktionstiegeloefen

    Energy Technology Data Exchange (ETDEWEB)

    Doetsch, Erwin; Forsthoevel, Christoph; Rische, Marco [ABP Induction Systems GmbH, Dortmund (Germany)

    2013-03-15

    The immediate proximity of the metal melt, with a temperature of up to above, 1600 C, to the induction coil in inductive melting necessitates highly reliable monitoring systems, in order to prevent dangerous contact between the melt and the cooling-water-conducting copper section. Ground-fault monitoring, in which the electrical resistance between the melt and the coil is continuously measured, is a standard solution for this function. Everyday use of this long-established system has been made more dependable by automating a number of functions, and the system has also been adapted to modern plant technology, including synchronous tandem operation of two crucible furnaces from a common converter power supply, for example. Measurement of frequency and effective power, as a function of wall thickness, is a supplementary monitoring strategy. Processing of the measured data in the melt processor, in combination with visual assessment, permits appraisal of the integral crucible state and reliable estimation of the remaining service-life of the current crucible. (orig.)

  18. Fusion of Landsat TM and ground spectrometry data in monitoring of non-operating mine

    Science.gov (United States)

    Borisova, Denitsa; Nikolov, Hristo N.

    2009-09-01

    Surface mining activities in Europe are estimated to cover an area of 5-10 000 km2. In this paper we suggest that the availability of Landsat Thematic Mapper (TM) for Earth observation allows the collection of environmental and minerelated data for use in the planning and undertaking of mine restoration work on cost-effective basis. The advantage is that these data are acquired digitally and can be easily processed and utilized in various information formats. Important step in the data processing is the verification of airborne data. For this purpose ground spectrometry measurements of samples taken from test sites have been performed. In the last decade several mining areas and corresponding dumps are subject to reclamation process in Bulgaria. We focused our research on one of the most important in the copper production for 20 year period for our country - Asarel-Medet deposit. This mining complex consists of an open mine, the dumps and a processing plant. After ceasing the exploitation of Medet deposit in 1994 a rehabilitation program for soil cover and hydrographic network was established and launched. A continuous task is the monitoring of these activities from the beginning for at least 15 years period, which is to end this year. To process the data, which characterize the progress of the land cover restoration, several techniques, both standard, such as basic and advanced statistics, image enhancement and data fusion, and novel methods for supervised classification were used. The results obtained show that used data and the implemented approach are useful in environmental monitoring and are economically attractive for the company responsible for the ecological state of the region.

  19. An online operational rainfall-monitoring resource for epidemic malaria early warning systems in Africa

    Directory of Open Access Journals (Sweden)

    Ceccato Pietro

    2005-01-01

    Full Text Available Abstract Periodic epidemics of malaria are a major public health problem for many sub-Saharan African countries. Populations in epidemic prone areas have a poorly developed immunity to malaria and the disease remains life threatening to all age groups. The impact of epidemics could be minimized by prediction and improved prevention through timely vector control and deployment of appropriate drugs. Malaria Early Warning Systems are advocated as a means of improving the opportunity for preparedness and timely response. Rainfall is one of the major factors triggering epidemics in warm semi-arid and desert-fringe areas. Explosive epidemics often occur in these regions after excessive rains and, where these follow periods of drought and poor food security, can be especially severe. Consequently, rainfall monitoring forms one of the essential elements for the development of integrated Malaria Early Warning Systems for sub-Saharan Africa, as outlined by the World Health Organization. The Roll Back Malaria Technical Resource Network on Prevention and Control of Epidemics recommended that a simple indicator of changes in epidemic risk in regions of marginal transmission, consisting primarily of rainfall anomaly maps, could provide immediate benefit to early warning efforts. In response to these recommendations, the Famine Early Warning Systems Network produced maps that combine information about dekadal rainfall anomalies, and epidemic malaria risk, available via their Africa Data Dissemination Service. These maps were later made available in a format that is directly compatible with HealthMapper, the mapping and surveillance software developed by the WHO's Communicable Disease Surveillance and Response Department. A new monitoring interface has recently been developed at the International Research Institute for Climate Prediction (IRI that enables the user to gain a more contextual perspective of the current rainfall estimates by comparing them to

  20. Nordic TSOs' action plants in enhancing and monitoring demand response[Transmission System Operator

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-02-01

    Nordel has seen demand side flexibility and demand response (DR) to high prices as a necessity for the Nordic market model functioning. The importance of demand response is increasing while the power balance is tightening. Therefore, measures activating demand response have a high priority. In the report 'Peak Production Capability and Peak Load in the Nordic Electricity Market' (Summary and conclusions and Appendix 1) Nordel recommended that each TSO shall make an action plan for enhancing demand response and together with the other stakeholders develop procedures for systematic monitoring of demand response. The practical potential in the medium term was roughly estimated in the above mentioned Nordel report to about 12 000 MW in total. Every 10 % of the potential that can be activated (1 200 MW) equals about 2 % of the peak load in the Nordic countries. This report summarizes the action plans and measures taken by the TSOs so far. In addition, other joint activities going on within Nordel as regards demand response and its systematic monitoring are summarized. In this context, measures aiming at more efficient utilisation of the local back-up generation are also included. By definition back-up generation is not a demand resource, but it is often discussed in the same context, because it is a resource that is dispersed located and controlled by the end-users. Increased local generation reduces need for transmission or distribution of power. For the activation of the back-up generation similar procedures are needed as to DR resources. (au)

  1. Combining modelled and remote sensing soil moisture anomalies for an operational global drought monitoring

    Science.gov (United States)

    Cammalleri, Carmelo; Vogt, Jürgen

    2017-04-01

    Soil moisture anomalies (i.e., deviations from the climatology) are often seen as a reliable tool to monitor and quantify the occurrence of drought events and their potential impacts, especially in agricultural and naturally vegetated lands. Soil moisture datasets (or their proxy) can be derived from a variety of sources, including land-surface models and thermal and microwave satellite remote sensing images. However, each data source has different advantages and drawbacks that prevent to unequivocally prefer one dataset over the others, especially in global applications that encompass a wide range of soil moisture regimes. The analysis of the spatial reliability of the different datasets at global scale is further complicated by the lack of reliable long-term soil moisture records for a ground validation over most regions. To overcome this limitation, in recent years the Triple Collocation (TC) technique has been deployed in order to quantify the likely errors associated to three mutually-independent datasets without assuming that one of them represents the "truth". In this study, three global datasets of soil moisture anomalies are investigated: the first one derived from the runs of the Lisflood hydrological model, the second one obtained from the combined active/passive microwave dataset produced in the framework of the European Space Agency (ESA) Climate Change Initiative (CCI), and the last one derived from the Moderate-Resolution Imaging Spectroradiometer (MODIS) Land Surface Temperature (LST) observations. A preliminary analysis of the three datasets aimed at detecting the areas where the TC technique can be successfully applied, hence the spatial distribution of the random error variance for each model is evaluated. This study allows providing useful advises for a robust combination of the three datasets into a single product for a more reliable global drought monitoring.

  2. Operative correction of judoists’ training loads on the base of on-line monitoring of heart beats rate

    Directory of Open Access Journals (Sweden)

    Liu Yong Qiang

    2015-02-01

    Full Text Available Purpose: ensure increase of effectiveness of training process’s control by means of operative correction of training loads of different qualification judo wrestlers’ heart beats rate indicators. Material: the research was conducted on the base of Brest SCJSOR № 1. Judo wrestlers of different sport qualification (age 17-19 years old, n=15 participated in the research. Monitoring of judo wrestlers’ heart beats rate was carried out with the help of system “Polar”. Results: we have found factorial structure of functional fitness in every profile of sportsmen. Model characteristics of judo wrestlers were supplemented with the most important sides of functional fitness. Analysis of indicators of restoration effectiveness indicators (REI in both groups of judo wrestlers showed high level of organism’s responsiveness to training load of special and power orientation in comparison with speed power load. We have worked out algorithm of operative correction of training loads by indicators of heart beats rate in training process, depending on orientation and intensity of loads’ physiological influence on judo wrestler. Conclusions: Telemetric on-line monitoring of sportsman’s heart beats rate and calculation of REI permit to objectively assess effectiveness of training’s construction and of micro-cycle in total and detect in due time the trend to development of over-loading and failure of adaptation.

  3. A Data Filter for Identifying Steady-State Operating Points in Engine Flight Data for Condition Monitoring Applications

    Science.gov (United States)

    Simon, Donald L.; Litt, Jonathan S.

    2010-01-01

    This paper presents an algorithm that automatically identifies and extracts steady-state engine operating points from engine flight data. It calculates the mean and standard deviation of select parameters contained in the incoming flight data stream. If the standard deviation of the data falls below defined constraints, the engine is assumed to be at a steady-state operating point, and the mean measurement data at that point are archived for subsequent condition monitoring purposes. The fundamental design of the steady-state data filter is completely generic and applicable for any dynamic system. Additional domain-specific logic constraints are applied to reduce data outliers and variance within the collected steady-state data. The filter is designed for on-line real-time processing of streaming data as opposed to post-processing of the data in batch mode. Results of applying the steady-state data filter to recorded helicopter engine flight data are shown, demonstrating its utility for engine condition monitoring applications.

  4. Bacteriophage removal efficiency as a validation and operational monitoring tool for virus reduction in wastewater reclamation: Review.

    Science.gov (United States)

    Amarasiri, Mohan; Kitajima, Masaaki; Nguyen, Thanh H; Okabe, Satoshi; Sano, Daisuke

    2017-09-15

    The multiple-barrier concept is widely employed in international and domestic guidelines for wastewater reclamation and reuse for microbiological risk management, in which a wastewater reclamation system is designed to achieve guideline values of the performance target of microbe reduction. Enteric viruses are one of the pathogens for which the target reduction values are stipulated in guidelines, but frequent monitoring to validate human virus removal efficacy is challenging in a daily operation due to the cumbersome procedures for virus quantification in wastewater. Bacteriophages have been the first choice surrogate for this task, because of the well-characterized nature of strains and the presence of established protocols for quantification. Here, we performed a meta-analysis to calculate the average log10 reduction values (LRVs) of somatic coliphages, F-specific phages, MS2 coliphage and T4 phage by membrane bioreactor, activated sludge, constructed wetlands, pond systems, microfiltration and ultrafiltration. The calculated LRVs of bacteriophages were then compared with reported human enteric virus LRVs. MS2 coliphage LRVs in MBR processes were shown to be lower than those of norovirus GII and enterovirus, suggesting it as a possible validation and operational monitoring tool. The other bacteriophages provided higher LRVs compared to human viruses. The data sets on LRVs of human viruses and bacteriophages are scarce except for MBR and conventional activated sludge processes, which highlights the necessity of investigating LRVs of human viruses and bacteriophages in multiple treatment unit processes. Copyright © 2017 Elsevier Ltd. All rights reserved.

  5. Design and operation of a comprehensive and permanent rock slope deformation monitoring system at the Great Aletsch Glacier (Switzerland)

    Science.gov (United States)

    Glueer, Franziska; Loew, Simon; Seifert, Reto; Frukacz, Mariusz; Wieser, Andreas

    2015-04-01

    Most geodetic monitoring systems of rock slope instabilities include a series of stable reference points. However, detailed studies of Alpine rock slopes with long term Global Navigation Satellite Systems (GNSS), high-resolution tilt meters and Total Stations (TPS) have shown unequivocally, that truly stable points are very rare. The underlying causes of such natural movements are long- and short-periodic reversible deformations of stable slopes caused by annual and daily changes of pore pressure and temperature in fractured rock masses. These movements impact TPS measurements and cause inconsistencies in the reference frame which, if not accounted for, will introduce systematic errors in the calculated deformation pattern and time series. This complex situation can be found in many mountain slopes. However, detailed measurements and analyses of the superposition of reversible slope deformations and gravitational mass movements of active instabilities are not existing. At the terminus of the Great Aletsch Glacier a comprehensive permanent deformation and displacement monitoring system has been installed, which allows to investigate large scale reversible deformations as well as active rock slope instabilities (Moosfluh and Driest) in response to rapid glacier retreat. The system includes 2 high-precision TPS stations with automated reflector recognition, 58 reflectors, 4 GNSS stations, climate sensors, and 2 high-resolution tilt meters and provides a fully automated survey with high accuracies over distances up to 2 km. The self-sustaining monitoring systems at Aletsch are installed at two high-alpine locations, remotely operated and automatically collect data on a set time schedule mainly at night. Deformation artefacts from thermal and wind disturbances of total stations' pillars and climatic refraction are studied with separate monitoring programs. We describe various aspects of the design, construction, testing and practical operation of this unique monitoring

  6. Generalised and regional soft tissue pain syndromes. The role of physical and rehabilitation medicine physicians. The European perspective based on the best evidence. A paper by the UEMS-PRM Section Professional Practice Committee.

    Science.gov (United States)

    Oral, A; Ilieva, E M; Küçükdeveci, A A; Varela, E; Valero, R; Berteanu, M; Christodoulou, N

    2013-08-01

    One of the objectives of the Professional Practice Committee (PPC) of the Physical and Rehabilitation Medicine (PRM) Section of the Union of European Medical Specialists (UEMS) is the development of the field of competence of PRM physicians in Europe. To achieve this objective, UEMS PRM Section PPC has adopted a systematic action plan of preparing a series of papers describing the role of PRM physicians in a number of disabling health conditions, based on the evidence of effectiveness of PRM interventions. Generalised and regional soft tissue pain syndromes constitute a major problem leading to loss of function and disability, resulting in enormous societal burden. The aim of this paper is to describe the unique role of PRM physicians in the management of these disabling conditions that require not only pharmacological interventions but also a holistic approach including the consideration of body functions, activities and participation as well as contextual factors as described in the ICF. Evidence-based effective PRM interventions include exercise and multicomponent treatment including a psychotherapeutic intervention such as cognitive behavioural therapy (CBT) in addition to exercise, the latter based on strong evidence for reducing pain and improving quality of life in fibromyalgia syndrome (FMS). Balneotherapy, meditative movement therapies, and acupuncture have also been shown as efficacious in improving symptoms in FMS. Emerging evidence suggests the use of transcranial magnetic or direct current stimulation (rTMS or tDCS) in FMS patients with intractable pain not alleviated by other interventions. Graded exercise therapy and CBT are evidence-based options for chronic fatigue syndrome. The use of some physical modalities and manipulation for myofascial pain syndrome is also supported by evidence. As for complex regional pain syndrome (CRPS), strong evidence exists for rTMS and graded motor imagery as well as moderate evidence for mirror therapy

  7. AATSR - Precise Sea-Surface Temperature for Climate Monitoring and for Operational Applications

    Science.gov (United States)

    Llewellyn-Jones, David; Corlett, Gary; Donlon, Craig; Stark, John

    The Advanced Along-Track Scanning Radiometer (AATSR) is an imaging radiometer specifi- cally designed to measure Sea-Surface Temperature (SST) to the demanding levels of accuracy and stability required for climate research. AATSR, which has been operating continuously on ESA's Envisat Satellite since its launch in 2002, achieves the required levels of accuracy on account of its unique dual view, whereby each terrestrial scene is viewed twice, once at nadir and then through an inclined path which uses a different atmospheric path-length, thereby providing a direct observation of atmospheric effects, leading to an exceptionally accurate atmospheric correction. This feature is accompanied by an advanced calibration system combined with excellent optical and thermal designs. Recent rigorous and extensive comparisons with in situ data have shown that, for most of the global oceans, AATSR can achieve and accuracy of around 0.2o C with high stability, which has qualified them for use in climate analysis schemes. Because AATSR is the third sensor in a near-continuous series which started with the launch of ATSR-1 on ERS-1 satellite in 1991, there is a time-series of 16+ years of climate standard SSTs which have recently been re-processed and are now becoming available to the World-wide user community from data centres in Europe. SST data from AATSR have been included in the suite of operational SST products generated by the GODAE/GHRSST Pilot Project, on a timescale needed by operational users and in a format which allows easy ingestion and error estimates for data from AATSR and most of the other sensors currently providing SST measurements from space. Within the GODAE/GHRSST data-products, AATSR SST data are generally regarded as the benchmark for accuracy and are used to provide bias corrections for data from the other sensors, which often have superior coverage, thus exploiting synergistically the complementary qualities if the different data-sets. The UK Met Office

  8. Development of a Portable Oxygen Monitoring System for Operations in the International Space Station Airlock

    Science.gov (United States)

    Graf, John

    2009-01-01

    NASA is currently engaged in an activity to facilitate effective operations on the International Space Station (ISS) after the Space Shuttle retires. Currently, the Space Shuttle delivers crew and cargo to and from ISS. The Space Shuttle provides the only large scale method of hardware return from ISS to the ground. Hardware that needs to be periodically repaired, refurbished, or recalibrated must come back from ISS on the Shuttle. One example of NASA flight hardware that is used on ISS and refurbished on the ground is the Compound Specific Analyzer for Oxygen (CSA-O2). The CSA-O2 is an electrochemical sensor that is used on orbit for about 12 months (depending on Shuttle launch schedules), then returned to the ground for sensor replacement. The shuttle is scheduled to retire in 2010, and the ISS is scheduled to operate until 2016. NASA needs a hand held sensor that measures oxygen in the ISS environment and has a 5-10 year service life. After conducting a survey of oxygen sensor systems, NASA selected a Tunable Diode Laser Absorption Spectrometer (TDLAS) as the method of measurement that best addresses the needs for ISS. These systems are compact, meet ISS accuracy requirements, and because they use spectroscopic techniques, the sensors are not consumed or altered after making a measurement. TDLAS systems have service life ratings of 5-10 years, based on the lifetime of the laser. NASA is engaged in modifying a commercially available sensor, the Vaisala OMT 355, for the ISS application. The Vaisala OMT 355 requires three significant modifications to meet ISS needs. The commercial sensor uses a wall mount power supply, and the ISS sensor needs to use a rechargeable battery as its source of power. The commercial sensor has a pressure correction setpoint: the sensor can be adjusted to operate at reduced pressure conditions, but the sensor does not self correct dynamically and automatically. The ISS sensor needs to operate in the airlock, and make accurate

  9. Microorganisms in Confined Habitats: Microbial Monitoring and Control of Intensive Care Units, Operating Rooms, Cleanrooms and the International Space Station.

    Science.gov (United States)

    Mora, Maximilian; Mahnert, Alexander; Koskinen, Kaisa; Pausan, Manuela R; Oberauner-Wappis, Lisa; Krause, Robert; Perras, Alexandra K; Gorkiewicz, Gregor; Berg, Gabriele; Moissl-Eichinger, Christine

    2016-01-01

    Indoor environments, where people spend most of their time, are characterized by a specific microbial community, the indoor microbiome. Most indoor environments are connected to the natural environment by high ventilation, but some habitats are more confined: intensive care units, operating rooms, cleanrooms and the international space station (ISS) are extraordinary living and working areas for humans, with a limited exchange with the environment. The purposes for confinement are different: a patient has to be protected from infections (intensive care unit, operating room), product quality has to be assured (cleanrooms), or confinement is necessary due to extreme, health-threatening outer conditions, as on the ISS. The ISS represents the most secluded man-made habitat, constantly inhabited by humans since November 2000 - and, inevitably, also by microorganisms. All of these man-made confined habitats need to be microbiologically monitored and controlled, by e.g., microbial cleaning and disinfection. However, these measures apply constant selective pressures, which support microbes with resistance capacities against antibiotics or chemical and physical stresses and thus facilitate the rise of survival specialists and multi-resistant strains. In this article, we summarize the available data on the microbiome of aforementioned confined habitats. By comparing the different operating, maintenance and monitoring procedures as well as microbial communities therein, we emphasize the importance to properly understand the effects of confinement on the microbial diversity, the possible risks represented by some of these microorganisms and by the evolution of (antibiotic) resistances in such environments - and the need to reassess the current hygiene standards.

  10. Microorganisms in confined habitats: Microbial monitoring and control of intensive care units, operating rooms, cleanrooms and the International Space Station

    Directory of Open Access Journals (Sweden)

    Maximilian Mora

    2016-10-01

    Full Text Available Indoor environments, where people spend most of their time, are characterized by a specific microbial community, the indoor microbiome. Most indoor environments are connected to the natural environment by high ventilation, but some habitats are more confined: intensive care units, operating rooms, cleanrooms and the international space station (ISS are extraordinary living and working areas for humans, with a limited exchange with the environment. The purposes for confinement are different: a patient has to be protected from infections (intensive care unit, operating room, product quality has to be assured (cleanrooms, or confinement is necessary due to extreme, health-threatening outer conditions, as on the ISS. The ISS represents the most secluded man-made habitat, constantly inhabited by humans since November 2000 – and, inevitably, also by microorganisms. All of these man-made confined habitats need to be microbiologically monitored and controlled, by e.g. microbial cleaning and disinfection. However, these measures apply constant selective pressures, which support microbes with resistance capacities against antibiotics or chemical and physical stresses and thus facilitate the rise of survival specialists and multi-resistant strains. In this article, we summarize the available data on the microbiome of aforementioned confined habitats. By comparing the different operating, maintenance and monitoring procedures as well as microbial communities therein, we emphasize the importance to properly understand the effects of confinement on the microbial diversity, the possible risks represented by some of these microorganisms and by the evolution of (antibiotic resistances in such environments - and the need to reassess the current hygiene standards.

  11. Monitoring dioxins and furans in subjects living in the vicinity of a hazardous waste incinerator after 4 years of operation

    Energy Technology Data Exchange (ETDEWEB)

    Bocio, A.; Domingo, J.L.; Garcia, F.; Schuhmacher, M.; Llobet, J.M. [Lab. of Toxicology and Environmental Health, Reus (Spain)

    2004-09-15

    In 1996, construction of a hazardous waste incinerator (HWI) was initiated in Constanti, Tarragona, Spain. Because this facility was the first, and up to date, the only HWI in Spain, the concern about its potential environmental impact and health risks has been considerable in the public opinion. Regular operations in the facility started in 1999. In order to establish the potential health risks of PCDD/PCDF exposure on the general population living near the new HWI, a biological monitoring program was designed. Samples of blood, breast milk and adipose tissue were obtained during the construction period of the HWI from subjects living in the neighborhood of the facility and analyzed for baseline levels of PCDD/PCDF. Moreover, taking into account that food is the main route of exposure to PCDD/Fs, the assessment of the dietary intake of these pollutants by the population living in the area under potential influence of the HWI was also included in the monitoring program. Approximately 4 years after the new HWI began regular operations (2003), biological samples from individuals living in the same area were again collected, and PCDD/PCDF concentrations determined. The update of PCDD/PCDF intake from food is essential in order to establish clearly if any potential increase in the levels of these compounds in biological tissues of individuals living in the area under influence of the HWI could be due to environmental emissions of PCDD/PCDF by the facility or to increases of the levels of these pollutants in food. In this paper, we present the concentrations of PCDD/PCDF in biological human samples from subjects living in the vicinity of the HWI. The dietary intake of these compounds by the population in this area, after 4 years of regular operations, is also shown. Results were compared with baseline PCDD/PCDF levels obtained in 1999.

  12. A new, long-term daily satellite-based rainfall dataset for operational monitoring in Africa

    Science.gov (United States)

    Maidment, Ross I.; Grimes, David; Black, Emily; Tarnavsky, Elena; Young, Matthew; Greatrex, Helen; Allan, Richard P.; Stein, Thorwald; Nkonde, Edson; Senkunda, Samuel; Alcántara, Edgar Misael Uribe

    2017-05-01

    Rainfall information is essential for many applications in developing countries, and yet, continually updated information at fine temporal and spatial scales is lacking. In Africa, rainfall monitoring is particularly important given the close relationship between climate and livelihoods. To address this information gap, this paper describes two versions (v2.0 and v3.0) of the TAMSAT daily rainfall dataset based on high-resolution thermal-infrared observations, available from 1983 to the present. The datasets are based on the disaggregation of 10-day (v2.0) and 5-day (v3.0) total TAMSAT rainfall estimates to a daily time-step using daily cold cloud duration. This approach provides temporally consistent historic and near-real time daily rainfall information for all of Africa. The estimates have been evaluated using ground-based observations from five countries with contrasting rainfall climates (Mozambique, Niger, Nigeria, Uganda, and Zambia) and compared to other satellite-based rainfall estimates. The results indicate that both versions of the TAMSAT daily estimates reliably detects rainy days, but have less skill in capturing rainfall amount—results that are comparable to the other datasets.

  13. Upgrade of the LHC Schottky Monitor, Operational Experience and First Results

    CERN Document Server

    Betz, Michael; Lefèvre, Thibaut; Wendt, Manfred

    2016-01-01

    The LHC Schottky system allows the measurement of beam parameters such as tune and chromaticity in an entirely non-invasive way by extracting information from the statistical fluctuations in the incoherent motion of particles. The system was commissioned in 2011 and provided satisfactory beam-parameter measurements during LHC run 1 for lead-ions. However, for protons its usability was substantially limited due to strong interfering signals originating from the coherent motion of the particle bunch. The system has recently been upgraded with optimized travelling-wave pick-ups and an improved 4.8~GHz microwave signal path, with the front-end and the triple down-mixing chain optimized to reduce coherent signals. Design and operational aspects for the complete system are shown and the results from measurements with LHC beams in Run II are presented and discussed.

  14. A Computer-aided Application for Modeling and Monitoring Operational and Maintenance Information in Mining Trucks

    Science.gov (United States)

    Nikulin, Christopher; Ulloa, Andres; Carmona, Carlos; Creixell, Werner

    2016-09-01

    The combination of maintenance planning and key performance indicators are relevant to create a more holistic scenario of the mining activities. On the one hand, reliability and maintainability are system characteristics suitable for planning maintenance strategies. On the other hand, key performance indicators are suitable to analyze cost and resource consumption information about mining equipment. Nevertheless in practice, both approaches are modeled separately and frequently by different team-works of a mining company. With this in mind, a computer-aided application was conceived to drive with better efficacy the operational and maintenance strategy in a complex process where the equipment is in continuous movement such as the transportation process in an open-mine pit.

  15. Detection and classification of alarm threshold violations in condition monitoring systems working in highly varying operational conditions

    Science.gov (United States)

    Strączkiewicz, M.; Barszcz, T.; Jabłoński, A.

    2015-07-01

    All commonly used condition monitoring systems (CMS) enable defining alarm thresholds that enhance efficient surveillance and maintenance of dynamic state of machinery. The thresholds are imposed on the measured values such as vibration-based indicators, temperature, pressure, etc. For complex machinery such as wind turbine (WT) the total number of thresholds might be counted in hundreds multiplied by the number of operational states. All the parameters vary not only due to possible machinery malfunctions, but also due to changes in operating conditions and these changes are typically much stronger than the former ones. Very often, such a behavior may lead to hundreds of false alarms. Therefore, authors propose a novel approach based on parameterized description of the threshold violation. For this purpose the novelty and severity factors are introduced. The first parameter refers to the time of violation occurrence while the second one describes the impact of the indicator-increase to the entire machine. Such approach increases reliability of the CMS by providing the operator with the most useful information of the system events. The idea of the procedure is presented on a simulated data similar to those from a wind turbine.

  16. Evaluating the Utility of Remotely-Sensed Soil Moisture Retrievals for Operational Agricultural Drought Monitoring

    Science.gov (United States)

    Bolten, John D.; Crow, Wade T.; Zhan, Xiwu; Jackson, Thomas J.; Reynolds,Curt

    2010-01-01

    Soil moisture is a fundamental data source used by the United States Department of Agriculture (USDA) International Production Assessment Division (IPAD) to monitor crop growth stage and condition and subsequently, globally forecast agricultural yields. Currently, the USDA IPAD estimates surface and root-zone soil moisture using a two-layer modified Palmer soil moisture model forced by global precipitation and temperature measurements. However, this approach suffers from well-known errors arising from uncertainty in model forcing data and highly simplified model physics. Here we attempt to correct for these errors by designing and applying an Ensemble Kalman filter (EnKF) data assimilation system to integrate surface soil moisture retrievals from the NASA Advanced Microwave Scanning Radiometer (AMSR-E) into the USDA modified Palmer soil moisture model. An assessment of soil moisture analysis products produced from this assimilation has been completed for a five-year (2002 to 2007) period over the North American continent between 23degN - 50degN and 128degW - 65degW. In particular, a data denial experimental approach is utilized to isolate the added utility of integrating remotely-sensed soil moisture by comparing EnKF soil moisture results obtained using (relatively) low-quality precipitation products obtained from real-time satellite imagery to baseline Palmer model runs forced with higher quality rainfall. An analysis of root-zone anomalies for each model simulation suggests that the assimilation of AMSR-E surface soil moisture retrievals can add significant value to USDA root-zone predictions derived from real-time satellite precipitation products.

  17. Geophysical Monitoring of Ground Surface Deformation Associated with a Confined Aquifer Storage and Recovery Operation

    Science.gov (United States)

    Bonneville, Alain; Heggy, Essam; Strickland, Christopher; Normand, Jonathan; Dermond, Jeffrey; Fang, Yilin; Sullivan, Charlotte

    2015-08-01

    One important issue in the storage of large volumes of fluids, mainly water and CO2, in the deep subsurface is to determine the resulting field-scale-induced displacements and consequences of overpressures on the mechanical integrity of the storage reservoir and surroundings. A quantifiable estimation of displacement can be made by combining the robust, cost-effective, and repeatable geophysical techniques of micro-gravimetry, differential global positioning system (DGPS), and differential synthetic aperture radar interferometry (DInSAR). These techniques were field tested and evaluated for the first time on an active large-volume aquifer storage and recovery (ASR) project in Pendleton, Oregon, USA, where three ASR wells are injecting up to 1.9 million m3 year-1 into basalt aquifers to a depth of about 150 m. Injection and recovery of water at the wells are accompanied by significant gravity anomalies and vertical deformation of the ground surface localized to the immediate surroundings of the injection wells as evidenced by DGPS and gravity measurements collected in 2011. At a larger scale, and between 2011 and 2013, DInSAR monitoring of the Pendleton area shows sub- centimetric deformation in the western part of the city and close to the injection locations associated with ASR cycle. Deformations are found to be temporally out phased with the injection and recovery events due to complex groundwater flow. A numerical simulation of the effect of the water injection gives results in good agreement with the observations and confirms the validity of the approach, which could be deployed in similar geological contexts to look at the mechanical effects of water and gas injections.

  18. A METHOD OF COMPLEX AUTOMATED MONITORING OF UKRAINIAN POWER ENERGY SYSTEM OBJECTS TO INCREASE ITS OPERATION SAFETY

    Directory of Open Access Journals (Sweden)

    Ye.I. Sokol

    2016-05-01

    Full Text Available The paper describes an algorithm of the complex automated monitoring of Ukraine’s power energy system, aimed at ensuring safety of its personnel and equipment. This monitoring involves usage of unmanned aerial vehicles (UAVs for planned and unplanned registration status of power transmission lines (PTL and high-voltage substations (HVS. It is assumed that unscheduled overflights will be made in emergency situations on power lines. With the help of the UAV, pictures of transmission and HVS will be recorded from the air in the optical and infrared ranges, as well as strength of electric (EF and magnetic (MF fields will be measured along the route of flight. Usage specially developed software allows to compare the recorded pictures with pre-UAV etalon patterns corresponding to normal operation of investigated transmission lines and the HVSs. Such reference pattern together with the experimentally obtained maps of HVS’s protective grounding will be summarized in a single document – a passport of HVS and PTL. This passport must also contain the measured and calculated values of strength levels of EF and MF in the places where staff of power facilities stay as well as layout of equipment, the most vulnerable to the effects of electromagnetic interference. If necessary, as part of ongoing monitoring, recommendations will be given on the design and location of electromagnetic screens, reducing the levels of electromagnetic interference as well as on location of lightning rods, reducing probability lightning attachment to the objects. The paper presents analytic expressions, which formed the basis of the developed software for calculation of the EF strength in the vicinity of power lines. This software will be used as a base at UAV navigation along the transmission lines, as well as to detect violations in the transmission lines operation. Comparison of distributions of EF strength calculated with the help of the elaborated software with the known

  19. Tethered Satellites as Enabling Platforms for an Operational Space Weather Monitoring System

    Science.gov (United States)

    Krause, L. Habash; Gilchrist, B. E.; Bilen, S.; Owens, J.; Voronka, N.; Furhop, K.

    2013-01-01

    Space weather nowcasting and forecasting models require assimilation of near-real time (NRT) space environment data to improve the precision and accuracy of operational products. Typically, these models begin with a climatological model to provide "most probable distributions" of environmental parameters as a function of time and space. The process of NRT data assimilation gently pulls the climate model closer toward the observed state (e.g. via Kalman smoothing) for nowcasting, and forecasting is achieved through a set of iterative physics-based forward-prediction calculations. The issue of required space weather observatories to meet the spatial and temporal requirements of these models is a complex one, and we do not address that with this poster. Instead, we present some examples of how tethered satellites can be used to address the shortfalls in our ability to measure critical environmental parameters necessary to drive these space weather models. Examples include very long baseline electric field measurements, magnetized ionospheric conductivity measurements, and the ability to separate temporal from spatial irregularities in environmental parameters. Tethered satellite functional requirements will be presented for each space weather parameter considered in this study.

  20. A Weekly Indicator of Surface Moisture Status from Satellite Data for Operational Monitoring of Crop Conditions

    Directory of Open Access Journals (Sweden)

    Francesco Nutini

    2017-06-01

    Full Text Available The triangle method has been applied to derive a weekly indicator of evaporative fraction on vegetated areas in a temperate region in Northern Italy. Daily MODIS Aqua Land Surface Temperature (MYD11A1 data has been combined with air temperature maps and 8-day composite MODIS NDVI (MOD13Q1/MYD13Q1 data to estimate the Evaporative Fraction (EF at 1 km resolution, on a daily basis. Measurements at two eddy covariance towers located within the study area have been exploited to assess the reliability of satellite based EF estimations as well as the robustness of input data. Weekly syntheses of the daily EF indicator (EFw were then derived at regional scale for the years 2010, 2011 and 2012 as a proxy of overall surface moisture condition. EFw showed a temporal behavior consistent with growing cycles and agro-practices of the main crops cultivated in the study area (rice, forages and corn. Comparison with official regional corn yield data showed that variations in EFw cumulated over summer are related with crop production shortages induced by water scarcity. These results suggest that weekly-averaged EF estimated from MODIS data is sensible to water stress conditions and can be used as an indicator of crops’ moisture conditions at agronomical district level. Advantages and disadvantages of the proposed approach to provide information useful to issue operational near real time bulletins on crop conditions at regional scale are discussed.

  1. A diagnostic signal selection scheme for planetary gearbox vibration monitoring under non-stationary operational conditions

    Science.gov (United States)

    Feng, Ke; Wang, KeSheng; Zhang, Mian; Ni, Qing; Zuo, Ming J.

    2017-03-01

    The planetary gearbox, due to its unique mechanical structures, is an important rotating machine for transmission systems. Its engineering applications are often in non-stationary operational conditions, such as helicopters, wind energy systems, etc. The unique physical structures and working conditions make the vibrations measured from planetary gearboxes exhibit a complex time-varying modulation and therefore yield complicated spectral structures. As a result, traditional signal processing methods, such as Fourier analysis, and the selection of characteristic fault frequencies for diagnosis face serious challenges. To overcome this drawback, this paper proposes a signal selection scheme for fault-emphasized diagnostics based upon two order tracking techniques. The basic procedures for the proposed scheme are as follows. (1) Computed order tracking is applied to reveal the order contents and identify the order(s) of interest. (2) Vold-Kalman filter order tracking is used to extract the order(s) of interest—these filtered order(s) constitute the so-called selected vibrations. (3) Time domain statistic indicators are applied to the selected vibrations for faulty information-emphasized diagnostics. The proposed scheme is explained and demonstrated in a signal simulation model and experimental studies and the method proves to be effective for planetary gearbox fault diagnosis.

  2. Tool Condition Monitoring and Remaining Useful Life Prognostic Based on a Wireless Sensor in Dry Milling Operations.

    Science.gov (United States)

    Zhang, Cunji; Yao, Xifan; Zhang, Jianming; Jin, Hong

    2016-05-31

    Tool breakage causes losses of surface polishing and dimensional accuracy for machined part, or possible damage to a workpiece or machine. Tool Condition Monitoring (TCM) is considerably vital in the manufacturing industry. In this paper, an indirect TCM approach is introduced with a wireless triaxial accelerometer. The vibrations in the three vertical directions (x, y and z) are acquired during milling operations, and the raw signals are de-noised by wavelet analysis. These features of de-noised signals are extracted in the time, frequency and time-frequency domains. The key features are selected based on Pearson's Correlation Coefficient (PCC). The Neuro-Fuzzy Network (NFN) is adopted to predict the tool wear and Remaining Useful Life (RUL). In comparison with Back Propagation Neural Network (BPNN) and Radial Basis Function Network (RBFN), the results show that the NFN has the best performance in the prediction of tool wear and RUL.

  3. Quality-by-Design approach to monitor the operation of a batch bioreactor in an industrial avian vaccine manufacturing process.

    Science.gov (United States)

    Largoni, Martina; Facco, Pierantonio; Bernini, Donatella; Bezzo, Fabrizio; Barolo, Massimiliano

    2015-10-10

    Monitoring batch bioreactors is a complex task, due to the fact that several sources of variability can affect a running batch and impact on the final product quality. Additionally, the product quality itself may not be measurable on line, but requires sampling and lab analysis taking several days to be completed. In this study we show that, by using appropriate process analytical technology tools, the operation of an industrial batch bioreactor used in avian vaccine manufacturing can be effectively monitored as the batch progresses. Multivariate statistical models are built from historical databases of batches already completed, and they are used to enable the real time identification of the variability sources, to reliably predict the final product quality, and to improve process understanding, paving the way to a reduction of final product rejections, as well as to a reduction of the product cycle time. It is also shown that the product quality "builds up" mainly during the first half of a batch, suggesting on the one side that reducing the variability during this period is crucial, and on the other side that the batch length can possibly be shortened. Overall, the study demonstrates that, by using a Quality-by-Design approach centered on the appropriate use of mathematical modeling, quality can indeed be built "by design" into the final product, whereas the role of end-point product testing can progressively reduce its importance in product manufacturing.

  4. The Navruz Project: Transboundary Monitoring for Radionuclides and Metals in Central Asia Rivers. Sampling and Analysis Plan and Operational Manual

    Energy Technology Data Exchange (ETDEWEB)

    Passell, Howard D.; Barber, David S.; Betsill, J. David; Littlfield, Adriane C.; Mohagheghi, Amir H.; Shanks, Sonoya T.; Yuldashev, Bekhzad; Salikhbaev, Umar; Radyuk, Raisa; Djuraev, Akram; Djuraev, Amwar; Vasilev, Ivan; Tolongutov, Bajgabyl; Valentina, Alekhina; Solodukhin, Vladimir; Pozniak, Victor

    2002-04-02

    The transboundary nature of water resources demands a transboundary approach to their monitoring and management. However, transboundary water projects raise a challenging set of problems related to communication issues, and standardization of sampling, analysis and data management methods. This manual addresses those challenges and provides the information and guidance needed to perform the Navruz Project, a cooperative, transboundary, river monitoring project involving rivers and institutions in Kazakhstan, Kyrgyzstan, Tajikistan, and Uzbekistan facilitated by Sandia National Laboratories in the U.S. The Navruz Project focuses on waterborne radionuclides and metals because of their importance to public health and nuclear materials proliferation concerns in the region. This manual provides guidelines for participants on sample and data collection, field equipment operations and procedures, sample handling, laboratory analysis, and data management. Also included are descriptions of rivers, sampling sites and parameters on which data are collected. Data obtained in this project are shared among all participating countries and the public through an internet web site, and are available for use in further studies and in regional transboundary water resource management efforts. Overall, the project addresses three main goals: to help increase capabilities in Central Asian nations for sustainable water resources management; to provide a scientific basis for supporting nuclear transparency and non-proliferation in the region; and to help reduce the threat of conflict in Central Asia over water resources, proliferation concerns, or other factors.

  5. Distributed Multi-Level Supervision to Effectively Monitor the Operations of a Fleet of Autonomous Vehicles in Agricultural Tasks

    Science.gov (United States)

    Conesa-Muñoz, Jesús; Gonzalez-de-Soto, Mariano; Gonzalez-de-Santos, Pablo; Ribeiro, Angela

    2015-01-01

    This paper describes a supervisor system for monitoring the operation of automated agricultural vehicles. The system analyses all of the information provided by the sensors and subsystems on the vehicles in real time and notifies the user when a failure or potentially dangerous situation is detected. In some situations, it is even able to execute a neutralising protocol to remedy the failure. The system is based on a distributed and multi-level architecture that divides the supervision into different subsystems, allowing for better management of the detection and repair of failures. The proposed supervision system was developed to perform well in several scenarios, such as spraying canopy treatments against insects and diseases and selective weed treatments, by either spraying herbicide or burning pests with a mechanical-thermal actuator. Results are presented for selective weed treatment by the spraying of herbicide. The system successfully supervised the task; it detected failures such as service disruptions, incorrect working speeds, incorrect implement states, and potential collisions. Moreover, the system was able to prevent collisions between vehicles by taking action to avoid intersecting trajectories. The results show that the proposed system is a highly useful tool for managing fleets of autonomous vehicles. In particular, it can be used to manage agricultural vehicles during treatment operations. PMID:25751079

  6. Distributed Multi-Level Supervision to Effectively Monitor the Operations of a Fleet of Autonomous Vehicles in Agricultural Tasks

    Directory of Open Access Journals (Sweden)

    Jesús Conesa-Muñoz

    2015-03-01

    Full Text Available This paper describes a supervisor system for monitoring the operation of automated agricultural vehicles. The system analyses all of the information provided by the sensors and subsystems on the vehicles in real time and notifies the user when a failure or potentially dangerous situation is detected. In some situations, it is even able to execute a neutralising protocol to remedy the failure. The system is based on a distributed and multi-level architecture that divides the supervision into different subsystems, allowing for better management of the detection and repair of failures. The proposed supervision system was developed to perform well in several scenarios, such as spraying canopy treatments against insects and diseases and selective weed treatments, by either spraying herbicide or burning pests with a mechanical-thermal actuator. Results are presented for selective weed treatment by the spraying of herbicide. The system successfully supervised the task; it detected failures such as service disruptions, incorrect working speeds, incorrect implement states, and potential collisions. Moreover, the system was able to prevent collisions between vehicles by taking action to avoid intersecting trajectories. The results show that the proposed system is a highly useful tool for managing fleets of autonomous vehicles. In particular, it can be used to manage agricultural vehicles during treatment operations.

  7. Design, installation, commissioning and operation of a beamlet monitor in the negative ion beam test stand at NIFS

    Energy Technology Data Exchange (ETDEWEB)

    Antoni, V.; Agostinetti, P.; Brombin, M.; Cervaro, V.; Delogu, R.; Fasolo, D.; Franchin, L.; Ghiraldelli, R.; Molon, F.; Pasqualotto, R.; Serianni, G., E-mail: gianluigi.serianni@igi.cnr.it; Tollin, M.; Veltri, P. [Consorzio RFX (CNR, ENEA, INFN, Università di Padova, Acciaierie Venete SpA) (Italy); De Muri, M. [Consorzio RFX (CNR, ENEA, INFN, Università di Padova, Acciaierie Venete SpA) (Italy); INFN-LNL, v.le dell' Università 2, I-35020, Legnaro (PD) Italy (Italy); Ikeda, K.; Kisaki, M.; Nakano, H.; Takeiri, Y.; Tsumori, K. [National Institute for Fusion Science, 322-6 Oroshi, Toki, Gifu 509-5292 (Japan); Muraro, A. [Istituto di Fisica del Plasma (IFP-CNR) – Via Cozzi 53, 20125, Milano (Italy)

    2015-04-08

    In the framework of the accompanying activity for the development of the two neutral beam injectors for the ITER fusion experiment, an instrumented beam calorimeter is being designed at Consorzio RFX, to be used in the SPIDER test facility (particle energy 100keV; beam current 50A), with the aim of testing beam characteristics and to verify the source proper operation. The main components of the instrumented calorimeter are one-directional carbon-fibre-carbon composite tiles. Some prototype tiles have been used as a small-scale version of the entire calorimeter in the test stand of the neutral beam injectors of the LHD experiment, with the aim of characterising the beam features in various operating conditions. The extraction system of the NIFS test stand source was modified, by applying a mask to the first gridded electrode, in order to isolate only a subset of the beamlets, arranged in two 3×5 matrices, resembling the beamlet groups of the ITER beam sources. The present contribution gives a description of the design of the diagnostic system, including the numerical simulations of the expected thermal pattern. Moreover the dedicated thermocouple measurement system is presented. The beamlet monitor was successfully used for a full experimental campaign, during which the main parameters of the source, mainly the arc power and the grid voltages, were varied. This contribution describes the methods of fitting and data analysis applied to the infrared images of the camera to recover the beamlet optics characteristics, in order to quantify the response of the system to different operational conditions. Some results concerning the beamlet features are presented as a function of the source parameters.

  8. Design, installation, commissioning and operation of a beamlet monitor in the negative ion beam test stand at NIFS

    Science.gov (United States)

    Antoni, V.; Agostinetti, P.; Brombin, M.; Cervaro, V.; Delogu, R.; De Muri, M.; Fasolo, D.; Franchin, L.; Ghiraldelli, R.; Ikeda, K.; Kisaki, M.; Molon, F.; Muraro, A.; Nakano, H.; Pasqualotto, R.; Serianni, G.; Takeiri, Y.; Tollin, M.; Tsumori, K.; Veltri, P.

    2015-04-01

    In the framework of the accompanying activity for the development of the two neutral beam injectors for the ITER fusion experiment, an instrumented beam calorimeter is being designed at Consorzio RFX, to be used in the SPIDER test facility (particle energy 100keV; beam current 50A), with the aim of testing beam characteristics and to verify the source proper operation. The main components of the instrumented calorimeter are one-directional carbon-fibre-carbon composite tiles. Some prototype tiles have been used as a small-scale version of the entire calorimeter in the test stand of the neutral beam injectors of the LHD experiment, with the aim of characterising the beam features in various operating conditions. The extraction system of the NIFS test stand source was modified, by applying a mask to the first gridded electrode, in order to isolate only a subset of the beamlets, arranged in two 3×5 matrices, resembling the beamlet groups of the ITER beam sources. The present contribution gives a description of the design of the diagnostic system, including the numerical simulations of the expected thermal pattern. Moreover the dedicated thermocouple measurement system is presented. The beamlet monitor was successfully used for a full experimental campaign, during which the main parameters of the source, mainly the arc power and the grid voltages, were varied. This contribution describes the methods of fitting and data analysis applied to the infrared images of the camera to recover the beamlet optics characteristics, in order to quantify the response of the system to different operational conditions. Some results concerning the beamlet features are presented as a function of the source parameters.

  9. The Earthscope USArray Array Network Facility (ANF): Metadata, Network and Data Monitoring, Quality Assurance During the Second Year of Operations

    Science.gov (United States)

    Eakins, J. A.; Vernon, F. L.; Martynov, V.; Newman, R. L.; Cox, T. A.; Lindquist, K. L.; Hindley, A.; Foley, S.

    2005-12-01

    The Array Network Facility (ANF) for the Earthscope USArray Transportable Array seismic network is responsible for: the delivery of all Transportable Array stations (400 at full deployment) and telemetered Flexible Array stations (up to 200) to the IRIS Data Management Center; station command and control; verification and distribution of metadata; providing useful remotely accessible world wide web interfaces for personnel at the Array Operations Facility (AOF) to access state of health information; and quality control for all data. To meet these goals, we use the Antelope software package to facilitate data collection and transfer, generation and merging of the metadata, real-time monitoring of dataloggers, generation of station noise spectra, and analyst review of individual events. Recently, an Antelope extension to the PHP scripting language has been implemented which facilitates the dynamic presentation of the real-time data to local web pages. Metadata transfers have been simplified by the use of orb transfer technologies at the ANF and receiver end points. Web services are being investigated as a means to make a potentially complicated set of operations easy to follow and reproduce for each newly installed or decommissioned station. As part of the quality control process, daily analyst review has highlighted areas where neither the regional network bulletins nor the USGS global bulletin have published solutions. Currently four regional networks (Anza, BDSN, SCSN, and UNR) contribute data to the Transportable Array with additional contributors expected. The first 100 stations (42 new Earthscope stations) were operational by September 2005 with all but one of the California stations installed. By year's end, weather permitting, the total number of stations deployed is expected to be around 145. Visit http://anf.ucsd.edu for more information on the project and current status.

  10. Study on path planning based on improved PRM method%基于改进PRM算法的路径规划研究

    Institute of Scientific and Technical Information of China (English)

    刘洋; 章卫国; 李广文

    2012-01-01

    为了解决传统PRM算法在处理窄通道问题时的缺陷,提出了一种改进的PRM算法.通过在规划环境中引入人工势场,对落在威胁体内的点施加势场力,使之移动到自由空间内,从而增加窄通道内的节点数量,在不增加采样次数的情况下完成路线图的构建.仿真结果表明,改进PRM算法提高了采样点的利用率,缩短了存在窄通道环境中的路径构建时间,在突发威胁时能快速完成路径生成.%This paper proposed an improved PRM, which focused on the problem of narrow passages in the configuration space. Considering the configuration space with narrow passages, it introduced the artificial potential field lo apply force to the initial points on the obstacle. The force drove these points to the free space. Then these points could be used to construct the roadmap. The roadmap could be gotten by less sampling. The simulation results shows that the improved PRM method can increase the planning efficiency. The improved PRM method enables road maps to reliably capture the connectivity of configuration spaces with narrow passages, and it performs well when the threaten break out.

  11. Prognostic value of intra-operative abnormal muscle response monitoring during microvascular decompression for long-term outcome of hemifacial spasm.

    Science.gov (United States)

    Li, Jiping; Zhang, Yuqing; Zhu, Hongwei; Li, Yongjie

    2012-01-01

    The reliability of intra-operative abnormal muscle response (AMR) monitoring as an indicator of post-operative outcome in patients with hemifacial spasm (HFS) is under debate. The primary aim of this study was to evaluate the correlation between intra-operative AMR changes and long-term post-operative outcome. We monitored intra-operative AMR during microvascular decompression (MVD) in consecutive patients with HFS (n = 104). Patients in this study were divided into two groups based on whether their AMR disappeared or persisted following MVD. Ninety patients were followed-up, and the mean duration from surgery to final follow-up examination was 3.7 years. Fourteen patients were lost to follow-up. AMR disappeared during surgery for 80 patients; of these, 74 achieved complete resolution of HFS, five had persistent HFS, and one patient developed a recurrence of HFS. Of the 10 patients with persistent AMR despite effective MVD, eight patients achieved complete resolution, one patient had persistent HFS, and one developed recurrent HFS. The long-term clinical outcome of HFS after MVD did not significantly correlate with intra-operative AMR changes (p = 0.791). Therefore, we suggest that intra-operative AMR monitoring may not be a reliable indicator of long-term post-operative outcome for HFS.

  12. Monitoring the natural attenuation of petroleum in ground water at the former naval complex, Operable Unit A, Adak Island, Alaska, May and June 2003

    Science.gov (United States)

    Dinicola, R.S.; Simonds, F.W.; Defawe, Rose

    2005-01-01

    During May and June 2003, the U.S. Geological Survey installed monitoring wells and collected data to characterize the effectiveness of natural attenuation processes for remediating petroleum-contaminated ground water at Operable Unit A of the former Naval complex on Adak Island, Alaska. In addition, the evidence for petroleum biodegradation in ground water was evaluated at selected petroleum sites, plans for future natural attenuation monitoring were suggested for the selected petroleum sites, and the natural attenuation monitoring strategy for the Downtown area of Adak Island was reviewed and refinements were suggested. U.S. Geological Survey personnel measured water levels and collected ground-water samples from about 100 temporary boreholes and 50 monitoring wells. Most samples were analyzed on-site for concentrations of selected petroleum compounds and natural attenuation parameters such as dissolved oxygen, ferrous iron, and carbon dioxide. The U.S. Geological Survey evaluated the data on-site, selected new monitoring well locations, and installed, developed, and sampled 10 monitoring wells. The review and suggestions for the natural attenuation monitoring strategy focused on how to better achieve monitoring objectives specified in the Record of Decision for Adak Island petroleum sites. To achieve the monitoring objective of verifying that natural attenuation is occurring, the monitoring plans for each monitored natural attenuation site need to include sampling of at least one strategically placed well at the downgradient margin of the contaminant plume margin, preferably where contaminant concentrations are detectable but less than the cleanup level. Collection of natural attenuation parameter data and sampling background wells is no longer needed to achieve the monitoring objective of demonstrating the occurrence of natural attenuation. To achieve the objective of monitoring locations where chemical concentrations exceed specified cleanup levels, at least

  13. Modeling the Relationship between Vibration Features and Condition Parameters Using Relevance Vector Machines for Health Monitoring of Rolling Element Bearings under Varying Operation Conditions

    Directory of Open Access Journals (Sweden)

    Lei Hu

    2015-01-01

    Full Text Available Rotational speed and load usually change when rotating machinery works. Both this kind of changing operational conditions and machine fault could make the mechanical vibration characteristics change. Therefore, effective health monitoring method for rotating machinery must be able to adjust during the change of operational conditions. This paper presents an adaptive threshold model for the health monitoring of bearings under changing operational conditions. Relevance vector machines (RVMs are used for regression of the relationships between the adaptive parameters of the threshold model and the statistical characteristics of vibration features. The adaptive threshold model is constructed based on these relationships. The health status of bearings can be indicated via detecting whether vibration features exceed the adaptive threshold. This method is validated on bearings running at changing speeds. The monitoring results show that this method is effective as long as the rotational speed is higher than a relative small value.

  14. IMPROVING THE SYSTEM OF MONITORING OF THE ASSETS AND OPERATIONS OF THE BANKING SECTOR IN COMBATING THE CRIMINAL RECEIPT OF INCOME

    Directory of Open Access Journals (Sweden)

    Irina N. Mihailova

    2014-01-01

    Full Text Available Important area for further information base work on combating money laundering is to extend the scope of financial monitoring by including in the number of organizations whose operations with monetary funds or other property subject to monitoring laundering, economic subjects, activity of which creates favorable conditions for laundering of such income. The Central place in countering unfair legalization given to the banking sector. In the scientific article is devoted to the topical issues of integration of system of financial monitoring and banking sector in the interests of solving the stated problem.

  15. Design, operation, and monitoring capability of an experimental artificial-recharge facility at East Meadow, Long Island, New York

    Science.gov (United States)

    Schneider, B.J.; Oaksford, E.T.

    1986-01-01

    Artificial recharge with tertiary-treated sewage is being tested at East Meadow to evaluate the physical and chemical effects on the groundwater system. The recharge facility contains 11 recharge basins and 5 injection wells and is designed to accept 4 million gallons of reclaimed water per day. Of the 11 basins, 7 are recently constructed and will accept 0.5 million gallons per day each. An observation manhole (12-foot inside diameter and extending 16 feet below the basin floor) was installed in each of two basins to enable monitoring and sampling of percolating reclaimed water in the unsaturated zone with instruments such as tensiometers, gravity lysimeters, thermocouples, and soil-gas samplers. Five shallow (100-feet deep) injection wells will each return 0.5 million gallons per day to the groundwater reservoir. Three types of injection-well design are being tested; the differences are in the type of gravel pack around the well screen. When clogging at the well screen occurs, redevelopment should restore the injection capability. Flow to the basins and wells is regulated by automatic flow controllers in which a desired flow rate is maintained by electronic sensors. Basins can also operate in a constant-head mode in which a specified head is maintained in the basin automatically. An observation-well network consisting of 2-inch- and 6-inch-diameter wells was installed within a 1-square-mile area at the recharge facility to monitor aquifer response and recharge. During 48 days of operation within a 17-week period (October 1982 through January 1983), 88.5 million gallons of reclaimed water was applied to the shallow water table aquifer through the recharge basins. A 4.29-foot-high groundwater mound developed during a 14-day test; some water level increase associated with the mound was detected 1,000 ft from the basins. Preliminary water quality data from wells affected by reclaimed water show evidence that mechanisms of mixing, dilution, and dispersion are

  16. Converter Compressor Building, SWMU 089, Hot Spot Areas 1, 2, and 5 Operations, Maintenance, and Monitoring Report, Kennedy Space Center, Florida

    Science.gov (United States)

    Wilson, Deborah M.

    2015-01-01

    This Operations, Maintenance, and Monitoring Report (OMMR) presents the findings, observations, and results from operation of the air sparging (AS) interim measure (IM) for Hot Spot (HS) Areas 1, 2, and 5 at the Converter Compressor Building (CCB) located at Kennedy Space Center (KSC), Florida. The objective of the IM at CCB HS Areas 1, 2, and 5 is to decrease concentrations of volatile organic compounds (VOCs) in groundwater in the treatment zones via AS to levels that will enable a transition to a monitored natural attenuation (MNA) phase. This OMMR presents system operations and maintenance (O&M) information and performance monitoring results since full-scale O&M began in June 2014 (2 months after initial system startup in April 2014), including quarterly performance monitoring events in July and October 2014 and January and May 2015. Based on the results to date, the AS system is operating as designed and is meeting the performance criteria and IM objective. The performance monitoring network is adequately constructed for assessment of IM performance at CCB HS Areas 1, 2, and 5. At the March 2014 KSC Remediation Team (KSCRT) Meeting, team consensus was reached for the design prepared for expansion of the system to treat the HS 4 area, and at the November 2014 KSCRT Meeting, team consensus was reached that HS 3 was adequately delineated horizontally and vertically and for selection of AS for the remedial approach for HS 3. At the July 2015 KSCRT meeting, team consensus was reached to continue IM operations in all zones until HSs 3 and 4 is operational, once HS 3 and 4 zones are operational discontinue operations in HS 1, 2, and 5 zones where concentrations are less than GCTLs to observe whether rebounding conditions occur. Team consensus was also reached to continue quarterly performance monitoring to determine whether operational zones achieve GCTLs and to continue annual IGWM of CCB-MW0012, CCBMW0013, and CCB-MW0056, located south of the treatment area. The

  17. Seasonal monitoring of deep-sea megabenthos in Barkley Canyon cold seep by internet operated vehicle (IOV).

    Science.gov (United States)

    Doya, Carolina; Chatzievangelou, Damianos; Bahamon, Nixon; Purser, Autun; De Leo, Fabio C; Juniper, S Kim; Thomsen, Laurenz; Aguzzi, Jacopo

    2017-01-01

    Knowledge of the processes shaping deep-sea benthic communities at seasonal scales in cold-seep environments is incomplete. Cold seeps within highly dynamic regions, such as submarine canyons, where variable current regimes may occur, are particularly understudied. Novel Internet Operated Vehicles (IOVs), such as tracked crawlers, provide new techniques for investigating these ecosystems over prolonged periods. In this study a benthic crawler connected to the NEPTUNE cabled infrastructure operated by Ocean Networks Canada was used to monitor community changes across 60 m2 of a cold-seep area of the Barkley Canyon, North East Pacific, at ~890 m depth within an Oxygen Minimum Zone (OMZ). Short video-transects were run at 4-h intervals during the first week of successive calendar months, over a 14 month period (February 14th 2013 to April 14th 2014). Within each recorded transect video megafauna abundances were computed and changes in environmental conditions concurrently measured. The responses of fauna to environmental conditions as a proxy of seasonality were assessed through analysis of abundances in a total of 438 video-transects (over 92 h of total footage). 7698 fauna individuals from 6 phyla (Cnidaria, Ctenophora, Arthropoda, Echinodermata, Mollusca, and Chordata) were logged and patterns in abundances of the 7 most abundant taxa (i.e. rockfish Sebastidae, sablefish Anoplopoma fimbria, hagfish Eptatretus stoutii, buccinids (Buccinoidea), undefined small crabs, ctenophores Bolinopsis infundibulum, and Scyphomedusa Poralia rufescens) were identified. Patterns in the reproductive behaviour of the grooved tanner crab (Chionnecetes tanneri) were also indicated. Temporal variations in biodiversity and abundance in megabenthic fauna was significantly influenced by variabilities in flow velocity flow direction (up or down canyon), dissolved oxygen concentration and month of study. Also reported here for the first time are transient mass aggregations of grooved tanner

  18. Simulation of the operational monitoring of a BWR with Simulate-3; Simulacion del seguimiento operacional de un reactor BWR con Simulate-3

    Energy Technology Data Exchange (ETDEWEB)

    Jimenez F, J. O.; Martin del Campo M, C.; Fuentes M, L.; Francois L, J. L., E-mail: ace.jo.cu@gmail.com [UNAM, Facultad de Ingenieria, Departamento de Sistemas Energeticos, Ciudad Universitaria, 04510 Ciudad de Mexico (Mexico)

    2015-09-15

    This work was developed in order to describe the methodology for calculating the fuel burned of nuclear power reactors throughout the duration of their operating cycle and for each fuel reload. In other words, simulate and give monitoring to the main operation parameters of sequential way along its operation cycles. For this particular case, the operational monitoring of five consecutive cycles of a reactor was realized using the information reported by their processes computer. The simulation was performed with the Simulate-3 software and the results were compared with those of the process computer. The goal is to get the fuel burned, cycle after cycle for obtain the state conditions of the reactor needed for the fuel reload analyses, stability studies and transients analysis, and the development of a methodology that allows to manage and resolve similar cases for future fuel cycles of the nuclear power plant and explore the various options offered by the simulator. (Author)

  19. Histidine at Residue 99 and the Transmembrane Region of the Precursor Membrane prM Protein Are Important for the prM-E Heterodimeric Complex Formation of Japanese Encephalitis Virus

    OpenAIRE

    Lin, Ying-Ju; Wu, Suh-Chin

    2005-01-01

    The formation of the flavivirus prM-E complex is an important step for the biogenesis of immature virions, which is followed by a subsequent cleavage of prM to M protein through cellular protease to result in the production and release of mature virions. In this study, the intracellular formation of the prM-E complex of Japanese encephalitis virus was investigated by baculovirus coexpression of prM and E in trans in Sf9 insect cells as analyzed by anti-E antibody immunoprecipitation and sucro...

  20. Operation of the CESR-TA vertical beam size monitor at $E_{\\rm b}$=4 GeV

    CERN Document Server

    Alexander, J P; Edwards, E; Flanagan, J W; Fontes, E; Heltsley, B K; Lyndaker, A; Peterson, D P; Rider, N T; Rubin, D L; Seeley, R; Shanks, J

    2015-01-01

    We describe operation of the CESR-TA vertical beam size monitor (xBSM) with $e^\\pm$ beams with $E_{\\rm b}$=4 GeV. The xBSM measures vertical beam size by imaging synchrotron radiation x-rays through an optical element onto a detector array of 32 InGaAs photodiodes with 50 $\\mu$m pitch. The device has previously been successfully used to measure vertical beam sizes of 10-100 $\\mu$m on a bunch-by-bunch, turn-by-turn basis at $e^\\pm$ beam energies of $\\sim$2 GeV and source magnetic fields below 2.8 kG, for which the detector required calibration for incident x-rays of 1-5 keV. At $E_{\\rm b}=4.0$ GeV and $B$=4.5 kG, however, the incident synchrotron radiation spectrum extends to $\\sim$20 keV, requiring calibration of detector response in that regime. Such a calibration is described and then used to analyze data taken with several different thicknesses of filters in front of the detector. We obtain a relative precision of better than 4% on beam size measurement from 15-100 $\\mu$m over several different ranges of x...

  1. Initial operation and current status of the Fermilab DZero VMEbus-based hardware control and monitor system

    Energy Technology Data Exchange (ETDEWEB)

    Goodwin, R.; Florian, R.; Johnson, M.; Jones, A.; Shea, M.

    1989-11-01

    DZero is a large colliding beams detector at Fermilab. The control system for this detector includes twenty-five VMEbus-based 68020 computers interconnected using the IEEE-802.5 Token Ring local area network. In operation, the system will monitor about fifteen thousand analog channels and several thousand digital status bits, interfaced to the 68020 computers by the MIL-1553 multiplexed data bus. In addition, the VMEbus control system uses a memory-mapped multi-VMEbus interconnect to download parameters to more than one hundred VMEbus data crates in the experiment. Remote host computers can then read and set memory in the detector crates over the network by accessing memory in the control crates. This is an extremely useful feature during the construction phase, because low level diagnostics and testing of all the detector electronics can be done over the Token Ring network using either IBM-PC compatible computers or the laboratory-wide VAX system. The VMEbus control system hardware is now being installed in the DZero movable counting house. Installation is expected to be complete later this year. 4 refs., 2 figs.

  2. Evaluación de híbridos experimentales de maíz del PRM en Centroamérica

    Directory of Open Access Journals (Sweden)

    Fidencio Guerra

    2003-01-01

    Full Text Available El ensayo de híbridos experimentales blancos del PRM-2001, fue evaluado durante el año 2001 en 14 localidades de Centroamérica. El objetivo de este trabajo fue evaluar el rendimiento de grano y características agron ómicas de los híbridos experimentales. Doce híbridos triples, uno doble, formados con cruzas simples de CIMMYT y líneas superiores de diferentes proyectos del Programa Regional de Maíz (PRM principalmente de híbridos y achaparramiento, incluida una entrada de referencia (CML 247 x CML 254 más un testigo local, fueron evaluados en un diseño experimental de bloques completos al azar, con tres repeticiones. Las variables registradas fueron rendimiento de grano, pudrición de mazorca, floración masculina y femenina, altura de planta y mazorca, cobertura y aspecto de mazorca, acame de raíz y tallo. Los resultados obtenidos para rendimiento de grano a través de los 14 ambientes fluctuaron entre 4, 75 a 6,37 t/ha con una media general de 5,60 t/ha y un coeficiente de variación de 9,9%. En pudrición de mazorca los híbridos presentaron valores de 4,3 y 8,0%, inferiores al testigo.

  3. 基于客户服务的机队运行监控系统开发%The Development of Operation Monitoring System Based on Customer Services

    Institute of Scientific and Technical Information of China (English)

    潘佑; 左洪福; 张营

    2011-01-01

    民用飞机的机队运行监控的目的是对机队的使用情况、可靠性状况等进行连续的监督与控制,以保证飞机安全的条件下,提高民用飞机的使用率和机队的使用可靠性水平。针对基于客户服务的新型民机运行监控系统的业务需求,设计了系统的功能结构和监控流程,分析了系统应采集的参数种类,阐述了系统采集参数的方法,并重点研究了运行监控系统的警告管理方法。%The operation monitoring of fleet aims to improve the utilization and reliability of fleet through monitoring the usage and reliability state of fleet continuously. Based on the requirements for the operation monitoring system of primary manufacturer, this paper designed the structure and monitoring process of the system, selected the type of parameters which collected in the system and provided the method of acquisition parameters. The warning management of operation monitoring system is described in detail.

  4. Operational monitoring and forecasting of bathing water quality through exploiting satellite Earth observation and models: The AlgaRisk demonstration service

    Science.gov (United States)

    Shutler, J. D.; Warren, M. A.; Miller, P. I.; Barciela, R.; Mahdon, R.; Land, P. E.; Edwards, K.; Wither, A.; Jonas, P.; Murdoch, N.; Roast, S. D.; Clements, O.; Kurekin, A.

    2015-04-01

    Coastal zones and shelf-seas are important for tourism, commercial fishing and aquaculture. As a result the importance of good water quality within these regions to support life is recognised worldwide and a number of international directives for monitoring them now exist. This paper describes the AlgaRisk water quality monitoring demonstration service that was developed and operated for the UK Environment Agency in response to the microbiological monitoring needs within the revised European Union Bathing Waters Directive. The AlgaRisk approach used satellite Earth observation to provide a near-real time monitoring of microbiological water quality and a series of nested operational models (atmospheric and hydrodynamic-ecosystem) provided a forecast capability. For the period of the demonstration service (2008-2013) all monitoring and forecast datasets were processed in near-real time on a daily basis and disseminated through a dedicated web portal, with extracted data automatically emailed to agency staff. Near-real time data processing was achieved using a series of supercomputers and an Open Grid approach. The novel web portal and java-based viewer enabled users to visualise and interrogate current and historical data. The system description, the algorithms employed and example results focussing on a case study of an incidence of the harmful algal bloom Karenia mikimotoi are presented. Recommendations and the potential exploitation of web services for future water quality monitoring services are discussed.

  5. 40 CFR 60.4237 - What are the monitoring requirements if I am an owner or operator of an emergency stationary SI...

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false What are the monitoring requirements if I am an owner or operator of an emergency stationary SI internal combustion engine? 60.4237 Section 60.4237 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW...

  6. Application of Time-Lapse Seismic Monitoring for the Control and Optimization of CO2 Enhanced Oil Recovery Operations

    Energy Technology Data Exchange (ETDEWEB)

    Brian Toelle

    2008-11-30

    This project, 'Application of Time-Lapse Seismic Monitoring for the Control and Optimization of CO{sub 2} Enhanced Oil Recovery Operations', investigated the potential for monitoring CO{sub 2} floods in carbonate reservoirs through the use of standard p-wave seismic data. This primarily involved the use of 4D seismic (time lapse seismic) in an attempt to observe and map the movement of the injected CO{sub 2} through a carbonate reservoir. The differences between certain seismic attributes, such as amplitude, were used for this purpose. This technique has recently been shown to be effective in CO{sub 2} monitoring in Enhanced Oil Recovery (EOR) projects, such as Weyborne. This study was conducted in the Charlton 30/31 field in the northern Michigan Basin, which is a Silurian pinnacle reef that completed its primary production in 1997 and was scheduled for enhanced oil recovery using injected CO{sub 2}. Prior to injection an initial 'Base' 3D survey was obtained over the field and was then processed and interpreted. CO{sub 2} injection within the main portion of the reef was conducted intermittently during 13 months starting in August 2005. During this time, 29,000 tons of CO{sub 2} was injected into the Guelph formation, historically known as the Niagaran Brown formation. By September 2006, the reservoir pressure within the reef had risen to approximately 2000 lbs and oil and water production from the one producing well within the field had increased significantly. The determination of the reservoir's porosity distribution, a critical aspect of reservoir characterization and simulation, proved to be a significant portion of this project. In order to relate the differences observed between the seismic attributes seen on the multiple 3D seismic surveys and the actual location of the CO{sub 2}, a predictive reservoir simulation model was developed based on seismic attributes obtained from the base 3D seismic survey and available well data. This

  7. A combined experimental and numerical approach for the control and monitoring of the SPES target during operation at high temperature

    Science.gov (United States)

    Ballan, Michele; Manzolaro, Mattia; Meneghetti, Giovanni; Andrighetto, Alberto; Monetti, Alberto; Bisoffi, Giovanni; Prete, Gianfranco

    2016-06-01

    The SPES project at INFN-LNL aims at the production of neutron-rich Radioactive Ion Beams (RIBs) using the ISOL (Isotope Separation On Line) technique. A 40 MeV 200 μA proton beam will directly impinge a uranium carbide target, generating approximately 1013 fissions per second. The target system is installed under vacuum inside a water-cooled chamber, and have to maintain high working temperatures, close to 2000 °C. During operation the proton beam provides the heating power required to keep the target at the desired temperature level. As a consequence, its characteristics have to be strictly controlled in order to avoid undesired overheating. According to the original design of the control system, the proton beam can be suddenly interrupted in case of out of range vacuum or cooling water flow levels. With the aim to improve the reliability of the control system a set of temperature sensors has been installed close to the target. Their types and installation positions were defined taking into consideration the detailed information coming from a dedicated thermal-electric model that allowed to investigate the most critical and inaccessible target hot-spots. This work is focused on the definition and experimental validation of the aforementioned numerical model. Its results were used to appropriately install two type C thermocouples, a PT100 thermo-resistance and a residual primary beam current detector. In addition the numerical model will be used for the definition of appropriate thresholds for each installed temperature sensor, since it allows to define a relationship between the locally measured values with the overall calculated temperature field. In case of over temperatures the monitoring system will send warning signals or in case interrupt the proton beam.

  8. LOCAD-PTS: Operation of a New System for Microbial Monitoring Aboard the International Space Station (ISS)

    Science.gov (United States)

    Maule, J.; Wainwright, N.; Steele, A.; Gunter, D.; Flores, G.; Effinger, M.; Danibm N,; Wells, M.; Williams, S.; Morris, H.; Monaco, L.

    2008-01-01

    Microorganisms within the space stations Salyut, Mir and the International Space Station (ISS), have traditionally been monitored with culture-based techniques. These techniques involve growing environmental samples (cabin water, air or surfaces) on agar-type media for several days, followed by visualization of resulting colonies; and return of samples to Earth for ground-based analysis. This approach has provided a wealth of useful data and enhanced our understanding of the microbial ecology within space stations. However, the approach is also limited by the following: i) More than 95% microorganisms in the environment cannot grow on conventional growth media; ii) Significant time lags occur between onboard sampling and colony visualization (3-5 days) and ground-based analysis (as long as several months); iii) Colonies are often difficult to visualize due to condensation within contact slide media plates; and iv) Techniques involve growth of potentially harmful microorganisms, which must then be disposed of safely. This report describes the operation of a new culture-independent technique onboard the ISS for rapid analysis (within minutes) of endotoxin and -1, 3-glucan, found in the cell walls of gram-negative bacteria and fungi, respectively. This technique involves analysis of environmental samples with the Limulus Amebocyte Lysate (LAL) assay in a handheld device. This handheld device and sampling system is known as the Lab-On-a-Chip Application Development Portable Test System (LOCAD-PTS). A poster will be presented that describes a comparative study between LOCAD-PTS analysis and existing culture-based methods onboard the ISS; together with an exploratory survey of surface endotoxin throughout the ISS. It is concluded that while a general correlation between LOCAD-PTS and traditional culture-based methods should not necessarily be expected, a combinatorial approach can be adopted where both sets of data are used together to generate a more complete story of

  9. Sequence-dependent upstream DNA-RNA polymerase interactions in the open complex with λPR λPRM promoters and implications for the mechanism of promoter interference

    Science.gov (United States)

    Mangiarotti, Laura; Cellai, Sara; Ross, Wilma; Bustamante, Carlos; Rivetti, Claudio

    2015-01-01

    The upstream interactions of Escherichia coli RNA polymerase in open complex (RPo) formed at the PR and PRM promoters of bacteriophage lambda, have been studied by atomic force microscopy (AFM). We demonstrate that the previously described 30 nm DNA compaction observed upon RPo formation at PR1 is a consequence of the specific interaction of the RNAP with two AT-rich sequence determinants positioned from −36 to −59 and from −80 to −100. Likewise, RPos formed at PRM showed a specific contact between the RNAP and the DNA sequence from −36 to −60. We further demonstrate that this interaction, which results in DNA wrapping against the polymerase surface, is mediated by the C-terminal domains of the alpha subunits (αCTD). Substitution of these AT-rich sequences with heterologous DNA reduces DNA wrapping but has little effect on the activity of the PR promoter. We find, however, that the frequency of DNA templates with both PR and PRM occupied by an RNAP significantly increases upon loss of DNA wrapping. These results suggest that αCTD interactions with upstream DNA can also play a role in regulating the expression of closely spaced promoters. Finally, a model for a possible mechanism of promoter interference between PR and PRM is proposed. PMID:19061900

  10. 40 CFR 63.4168 - What are the requirements for continuous parameter monitoring system installation, operation, and...

    Science.gov (United States)

    2010-07-01

    ... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL... monitor pressure drop across the zeolite wheel or rotary carbon bed. The pressure monitoring device must... pressure sensor(s) in or as close to a position that provides a representative measurement of the pressure...

  11. Early detection and treatment of myocardial ischaemia after operation using continual ambulatory arterial pressure monitoring and ECG ST segment analysis.

    Science.gov (United States)

    Edwards, N D; Troy, G; Yeo, W; Jackson, P; Reilly, C S

    1995-10-01

    We report a case in which the use of continual ambulatory arterial pressure monitoring and ECG ST-segment analysis allowed early detection and treatment of myocardial ischaemia in the postoperative period. We believe that this case illustrates the potential value of ambulatory monitoring in the early postoperative period in high-risk patients.

  12. Pirate stealth or inattentional blindness? The effects of target relevance and sustained attention on security monitoring for experienced and naive operators.

    Directory of Open Access Journals (Sweden)

    Erika Näsholm

    Full Text Available Closed Circuit Television (CCTV operators are responsible for maintaining security in various applied settings. However, research has largely ignored human factors that may contribute to CCTV operator error. One important source of error is inattentional blindness--the failure to detect unexpected but clearly visible stimuli when attending to a scene. We compared inattentional blindness rates for experienced (84 infantry personnel and naïve (87 civilians operators in a CCTV monitoring task. The task-relevance of the unexpected stimulus and the length of the monitoring period were manipulated between participants. Inattentional blindness rates were measured using typical post-event questionnaires, and participants' real-time descriptions of the monitored event. Based on the post-event measure, 66% of the participants failed to detect salient, ongoing stimuli appearing in the spatial field of their attentional focus. The unexpected task-irrelevant stimulus was significantly more likely to go undetected (79% than the unexpected task-relevant stimulus (55%. Prior task experience did not inoculate operators against inattentional blindness effects. Participants' real-time descriptions revealed similar patterns, ruling out inattentional amnesia accounts.

  13. Final Report: Baseline Selenium Monitoring of Agricultural Drains Operated by the Imperial Irrigation District in the Salton Sea Basin, California

    Science.gov (United States)

    Saiki, Michael K.; Martin, Barbara A.; May, Thomas W.

    2010-01-01

    This report summarizes comprehensive findings from a 4-year-long field investigation to document baseline environmental conditions in 29 agricultural drains and ponds operated by the Imperial Irrigation District along the southern border of the Salton Sea. Routine water-quality collections and fish community assessments were conducted on as many as 16 sampling dates at roughly quarterly intervals from July 2005 to April 2009. The water-quality measurements included total suspended solids and total (particulate plus dissolved) selenium. With one exception, fish were surveyed with baited minnow traps at quarterly intervals during the same time period. However, in July 2007, fish surveys were not conducted because we lacked permission from the California Department of Fish and Game for incidental take of desert pupfish (Cyprinodon macularius), an endangered species. During April and October 2006-08, water samples also were collected from seven intensively monitored drains (which were selected from the 29 total drains) for measurement of particulate and dissolved selenium, including inorganic and organic fractions. In addition, sediment, aquatic food chain matrices [particulate organic detritus, filamentous algae, net plankton, and midge (chironomid) larvae], and two fish species (western mosquitofish, Gambusia affinis; and sailfin molly, Poecilia latipinna) were sampled from the seven drains for measurement of total selenium concentrations. The mosquitofish and mollies were intended to serve as surrogates for pupfish, which we were not permitted to sacrifice for selenium determinations. Water quality (temperature, dissolved oxygen, pH, specific conductance, and turbidity) values were typical of surface waters in a hot, arid climate. A few drains exhibited brackish, near-anoxic conditions, especially during summer and fall when water temperatures occasionally exceeded 30 degrees Celsius. Total selenium concentrations in water were directly correlated with salinity and

  14. [Comparison of LCD and CRT monitors for detection of pulmonary nodules and interstitial lung diseases on digital chest radiographs by using receiver operating characteristic analysis].

    Science.gov (United States)

    Ikeda, Ryuji; Katsuragawa, Shigehiko; Shimonobou, Toshiaki; Hiai, Yasuhiro; Hashida, Masahiro; Awai, Kazuo; Yamashita, Yasuyuki; Doi, Kunio

    2006-05-20

    Soft copy reading of digital images has been practiced commonly in the PACS environment. In this study, we compared liquid-crystal display (LCD) and cathode-ray tube (CRT) monitors for detection of pulmonary nodules and interstitial lung diseases on digital chest radiographs by using receiver operating characteristic (ROC) analysis. Digital chest images with a 1000x1000 matrix size and a 8 bit grayscale were displayed on LCD/CRT monitor with 2M pixels in each observer test. Eight and ten radiologists participated in the observer tests for detection of nodules and interstitial diseases, respectively. In each observer test, radiologists marked their confidence levels for diagnosis of pulmonary nodules or interstitial diseases. The detection performance of radiologists was evaluated by ROC analyses. The average Az values (area under the ROC curve) in detecting pulmonary nodules with LCD and CRT monitors were 0.792 and 0.814, respectively. In addition, the average Az values in detecting interstitial diseases with LCD and CRT monitors were 0.951 and 0.953, respectively. There was no statistically significant difference between LCD and CRT for both detection of pulmonary nodules (P=0.522) and interstitial lung diseases (P=0.869). Therefore, we believe that the LCD monitor instead of the CRT monitor can be used for the diagnosis of pulmonary nodules and interstitial lung diseases in digital chest images.

  15. An increase in milk IgA correlates with both pIgR expression and IgA plasma cell accumulation in the lactating mammary gland of PRM/Alf mice.

    Science.gov (United States)

    Boumahrou, Nisrine; Chevaleyre, Claire; Berri, Mustapha; Martin, Patrice; Bellier, Sylvain; Salmon, Henri

    2012-12-01

    In mice, during late pregnancy and lactation, maternal precursors of IgA-containing cells (cIgA-cells) are primed in the gut and home to the mammary gland where they secrete IgA. In turn, the ensuing increase in milk IgA mediates immune protection of the newborn gastrointestinal tract. PRM/Alf is an inbred mouse strain which exhibits a substantial post-natal intestinal lengthening which develops throughout the neonatal suckling period, suggesting that the availability of cIg-A cells and the level of protective IgA in milk might also be increased. We confirmed that PRM/Alf milk contains higher amounts of IgA than C57BL/6J throughout lactation, concomitantly with an increase of pIgR on epithelial cells and a higher density of cIgA-cells in the PRM/Alf mammary gland. Furthermore, a search for variations in cellular and humoral factors implicated in regulating cIgA-cell migration towards the mammary gland, including the vascular addressins MAdCAM-1 (mucosal addressin cell adhesion molecule-1) and VCAM-1 (vascular cell adhesion molecule-1) as well as the mucosal epithelial chemokine CCL28, did not reveal any quantitative differences in expression between PRM/Alf and C57BL/6J mice strains. Thus our results indicate that these factors are not limiting in the recruitment of cIgA-cells released from the elongated gut of PRM/Alf mice. In the context of intestinal lengthening, these findings strengthen the notion of an entero-mammary gland link, where the neonatal gut is protected by the maternal gut through the immune function of the mammary gland.

  16. Parallel reaction monitoring using quadrupole-Orbitrap mass spectrometer: Principle and applications.

    Science.gov (United States)

    Bourmaud, Adele; Gallien, Sebastien; Domon, Bruno

    2016-08-01

    Targeted mass spectrometry-based approaches are nowadays widely used for quantitative proteomics studies and more recently have been implemented on high resolution/accurate mass (HRAM) instruments resulting in a considerable performance improvement. More specifically, the parallel reaction monitoring technique (PRM) performed on quadrupole-Orbitrap mass spectrometers, leveraging the high resolution and trapping capabilities of the instrument, offers a clear advantage over the conventional selected reaction monitoring (SRM) measurements executed on triple quadrupole instruments. Analyses performed in HRAM mode allow for an improved discrimination between signals derived from analytes and those resulting from matrix interferences translating in the reliable quantification of low abundance components. The purpose of the study defines various implementation schemes of PRM, namely: (i) exploratory experiments assessing the detectability of very large sets of peptides (100-1000), (ii) wide-screen analyses using (crude) internal standards to obtain statistically meaningful (relative) quantitative analyses, and (iii) precise/accurate quantification of a limited number of analytes using calibrated internal standards. Each of the three implementation schemes requires specific acquisition methods with defined parameters to appropriately control the acquisition during the actual peptide elution. This tutorial describes the different PRM approaches and discusses their benefits and limitations in terms of quantification performance and confidence in analyte identification.

  17. Continuous glucose monitoring system in the operating room and intensive care unit: any difference according to measurement sites?

    Science.gov (United States)

    Song, In-Kyung; Lee, Ji-Hyun; Kang, Joo-Eun; Park, Yang-Hyo; Kim, Hee-Soo; Kim, Jin-Tae

    2017-02-01

    Given the benefit of glucose control in the perioperative period, we evaluated the accuracy and performance of the continuous glucose monitoring system (CGMS) depending on different measurement sites in the operating room (OR) and in the intensive care unit (ICU). Patients over 18 years of age scheduled for elective surgery and ICU admission were enrolled prospectively. Two CGMS sensors were inserted into the subcutaneous tissue of the proximal lateral thigh and the lateral abdomen. The rate of successful measurements from thigh and abdomen in the OR and in the ICU were calculated separately. Each CGMS values were compared with the time-matched arterial blood glucose measurements. CGMS values from both measurement sites were also compared. A total of 22 patients undergoing cardiac surgeries were studied. The rate of successful measurements was higher in the ICU (73.2 %) than in the OR (66.0 %) (P = 0.01); however, that from thigh (72.9 %) and from abdomen (58.7 %) showed statistically significant difference only in the OR (P = 0.04). The Pearson correlation coefficient of thigh and abdomen versus arterial values was 0.67 and 0.60, respectively (P < 0.001). In Clarke error grid analysis, 94.6 % (89.3 % in the OR and 96.1 % in the ICU) of values from thigh fell into clinically acceptable zones compared to 93.7 % (89.0 % in the OR and 95.4 % in the ICU) from abdomen. There were no statistically significant differences in the accuracy according to measurement sites. The CGMS showed high measurement failure rate, especially in the OR. In the OR, the rate of successful measurement was higher from thigh than from abdomen. The CGMS showed low accuracy compared to arterial reference values. Nevertheless, there was no difference in the accuracy of the CGMS between two measurement sites. Perioperative performance of the CGMS still needs to be improved considering relatively low successful measurement rates.

  18. Baseline and Postremediation Monitoring Program Plan for the Lower East Fork Poplar Creek operable unit, Oak Ridge, Tennessee

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-04-01

    This report was prepared in accordance with CERCLA requirements to present the plan for baseline and postremediation monitoring as part of the selected remedy. It provides the Environmental Restoration Program with information about the requirements to monitor for soil and terrestrial biota in the Lower East Fork Poplar Creek (LEFPC) floodplain; sediment, surface water, and aquatic biota in LEFPC; wetland restoration in the LEFPC floodplain; and human use of shallow groundwater wells in the LEFPC floodplain for drinking water. This document describes the monitoring program that will ensure that actions taken under Phases I and II of the LEFPC remedial action are protective of human health and the environment.

  19. 基于障碍物边界采样改进的Visibility-PRM算法%An Improved Visibility-PRM Algorithm Based on Obstacle Boundary Sampling Method

    Institute of Scientific and Technical Information of China (English)

    宣俊; 林兰芬; 何臻锋

    2005-01-01

    首先分析解决机器人运动规划问题的Visibility-PRM算法.然后针对其在复杂工作空间运动规划中表现出的roadmap连通子图数多、可视性判断效率低等局限性,提出基于障碍物边界采样改进的Visibility-PRM算法(Obs-Visi-PRM).通过改进采样和连通的策略,减少了roadmap的连通子图数,降低了碰撞检测次数.最后通过实例分析,证明Obs-Visi-PRM算法的有效性.

  20. 杜比 PRM-4200专业视频效果测试校正仪荣获艾美奖

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    杜比PRM-4200专业视频效果测试校正仪荣获艾美奖标志着美国国家电视艺术与科学学院(NA—TAs)和美国电视艺术与科学学院(ATAS)第12次授予杜比产品技术奖项。杜比PRM-4200专为需要最精准测量工具从事对色彩要求很高的专业人士而设计,被公认为极精准视觉应用的新标准,完善了调色师与电影摄影师的创作过程,确保他们的最终图像与在屏幕上看到的完全一致。

  1. Water Eutrophication Risk Analysis Modeling Based on PRM%基于PRM的水体富营养化风险分析建模

    Institute of Scientific and Technical Information of China (English)

    范敏; 石为人

    2010-01-01

    从信息的知识发现角度出发,提出基于概率关系模型(PRM)的水体富营养化风险分析建模万法.该建模方法利用多关系数据的存储结构和存储内容对数据进行学习与挖掘,构建具有网络拓扑结构的PRM模型.示例分析结果表明,PRM模型易于解释与分析水体中各种影响因素间的相关性,该建模方法可通过分析历史数据发现水体富营养化的潜在风险,为库区水环境管理与水污染防治提供科学依据.

  2. The parallel reaction monitoring method contributes to a highly sensitive polyubiquitin chain quantification

    Energy Technology Data Exchange (ETDEWEB)

    Tsuchiya, Hikaru; Tanaka, Keiji, E-mail: tanaka-kj@igakuken.or.jp; Saeki, Yasushi, E-mail: saeki-ys@igakuken.or.jp

    2013-06-28

    Highlights: •The parallel reaction monitoring method was applied to ubiquitin quantification. •The ubiquitin PRM method is highly sensitive even in biological samples. •Using the method, we revealed that Ufd4 assembles the K29-linked ubiquitin chain. -- Abstract: Ubiquitylation is an essential posttranslational protein modification that is implicated in a diverse array of cellular functions. Although cells contain eight structurally distinct types of polyubiquitin chains, detailed function of several chain types including K29-linked chains has remained largely unclear. Current mass spectrometry (MS)-based quantification methods are highly inefficient for low abundant atypical chains, such as K29- and M1-linked chains, in complex mixtures that typically contain highly abundant proteins. In this study, we applied parallel reaction monitoring (PRM), a quantitative, high-resolution MS method, to quantify ubiquitin chains. The ubiquitin PRM method allows us to quantify 100 attomole amounts of all possible ubiquitin chains in cell extracts. Furthermore, we quantified ubiquitylation levels of ubiquitin-proline-β-galactosidase (Ub-P-βgal), a historically known model substrate of the ubiquitin fusion degradation (UFD) pathway. In wild-type cells, Ub-P-βgal is modified with ubiquitin chains consisting of 21% K29- and 78% K48-linked chains. In contrast, K29-linked chains are not detected in UFD4 knockout cells, suggesting that Ufd4 assembles the K29-linked ubiquitin chain(s) on Ub-P-βgal in vivo. Thus, the ubiquitin PRM is a novel, useful, quantitative method for analyzing the highly complicated ubiquitin system.

  3. Post-Closure Monitoring Report for Corrective Action Unit 339: Area 12 Fleet Operations Steam Cleaning Effluent Nevada Test Site, Nevada

    Energy Technology Data Exchange (ETDEWEB)

    K. B. Campbell

    2002-09-01

    The Area 12 Fleet Operations Steam Cleaning Effluent site is located in the southeastern portion of the Area 12 Camp at the Nevada Test Site. This site is identified in the Federal Facility Agreement and Consent Order (1996) as Corrective Action Site (CAS) 12-19-01 and is the only CAS assigned to Corrective Action Unit (CAU) 339. Post-closure sampling and inspection of the site were completed on March 27, 2002. Post-closure monitoring activities were scheduled biennially (every two years) in the Post-Closure Monitoring Plan provided in the Closure Report for CAU 339: Area 12 Fleet Operations Steam Cleaning Effluent, Nevada Test Site (U.S. Department of Energy, Nevada Operations Office [DOEN], 1997). A baseline for the site was established by sampling in 1997. Based on the recommendations from the 1999 post-closure monitoring report (DOE/NV, 1999), samples were collected in 2000, earlier than originally proposed, because the 1999 sample results did not provide the expected decrease in total petroleum hydrocarbon (TPH) concentrations at the site. Sampling results from 2000 (DOE/NV, 2000) and 2001 (DOE/NV, 2001) revealed favorable conditions for natural degradation at the CAU 339 site, but because of differing sample methods and heterogeneity of the soil, data results from 2000 and later were not directly correlated with previous results. Post-closure monitoring activities for 2002 consisted of the following: (1) Soil sample collection from three undisturbed plots (Plots A, B, and C, Figure 2). (2) Sample analysis for TPH as oil and bio-characterization parameters (Comparative Enumeration Assay [CEA] and Standard Nutrient Panel [SNP]). (3) Site inspection to evaluate the condition of the fencing and signs. (4) Preparation and submittal of the Post-Closure Monitoring Report.

  4. Analysing the Advantages of High Temporal Resolution Geostationary MSG SEVIRI Data Compared to Polar Operational Environmental Satellite Data for Land Surface Monitoring in Africa

    Science.gov (United States)

    Fensholt, R.; Anyamba, A.; Huber, S.; Proud, S. R.; Tucker, C. J.; Small, J.; Pak, E.; Rasmussen, M. O.; Sandholt, I.; Shisanya, C.

    2011-01-01

    Since 1972, satellite remote sensing of the environment has been dominated by polar-orbiting sensors providing useful data for monitoring the earth s natural resources. However their observation and monitoring capacity are inhibited by daily to monthly looks for any given ground surface which often is obscured by frequent and persistent cloud cover creating large gaps in time series measurements. The launch of the Meteosat Second Generation (MSG) satellite into geostationary orbit has opened new opportunities for land surface monitoring. The Spinning Enhanced Visible and Infrared Imager (SEVIRI) instrument on-board MSG with an imaging capability every 15 minutes which is substantially greater than any temporal resolution that can be obtained from existing polar operational environmental satellites (POES) systems currently in use for environmental monitoring. Different areas of the African continent were affected by droughts and floods in 2008 caused by periods of abnormally low and high rainfall, respectively. Based on the effectiveness of monitoring these events from Earth Observation (EO) data the current analyses show that the new generation of geostationary remote sensing data can provide higher temporal resolution cloud-free (less than 5 days) measurements of the environment as compared to existing POES systems. SEVIRI MSG 5-day continental scale composites will enable rapid assessment of environmental conditions and improved early warning of disasters for the African continent such as flooding or droughts. The high temporal resolution geostationary data will complement existing higher spatial resolution polar-orbiting satellite data for various dynamic environmental and natural resource applications of terrestrial ecosystems.

  5. Development of a majority vote decision module for a self-diagnostic monitoring system for an air-operated valve system

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Woo Shin [Dept. of Information and Communication Engineering, Sejong University, Seoul (Korea, Republic of); Chai, Jang Bom [Dept. of Mechanical Engineering, Ajou University, Suwon (Korea, Republic of); Kim, In Taek [Dept. of Information and Communication Engineering, Myongji University, Yongin (Korea, Republic of)

    2015-08-15

    A self-diagnostic monitoring system is a system that has the ability to measure various physical quantities such as temperature, pressure, or acceleration from sensors scattered over a mechanical system such as a power plant, in order to monitor its various states, and to make a decision about its health status. We have developed a self-diagnostic monitoring system for an air-operated valve system to be used in a nuclear power plant. In this study, we have tried to improve the self-diagnostic monitoring system to increase its reliability. We have implemented three different machine learning algorithms, i.e., logistic regression, an artificial neural network, and a support vector machine. After each algorithm performs the decision process independently, the decision-making module collects these individual decisions and makes a final decision using a majority vote scheme. With this, we performed some simulations and presented some of its results. The contribution of this study is that, by employing more robust and stable algorithms, each of the algorithms performs the recognition task more accurately. Moreover, by integrating these results and employing the majority vote scheme, we can make a definite decision, which makes the self-diagnostic monitoring system more reliable.

  6. Real-time monitoring and calculation of the derating of single-phase transformers under nonsinusoidal operation

    Science.gov (United States)

    Batan, Tufan

    The extensive use of power electronic devices in the last two decades have degraded the quality of the power system by introducing voltage and current harmonics as well as DC excitations. Such phenomena cause additional losses in transformers, resulting in elevated temperatures of transformers above their rated temperatures. This added heat degrades the insulating material of the windings, decreasing the rated lifetime of transformers. For this reason, transformers feeding nonlinear loads must be derated; that is. by limiting either their output apparent or real power such that rated temperatures are not exceeded. It is of advantage to measure the derating of transformers which are already in service, for given nonlinear loads and to calculate the derating of large transformers that cannot readily be tested in laboratories. It is one of the objectives of this thesis to validate the computed derating values of transformers with corroborating measurements. A 25kVA 7200V/240V single-phase pole transformer is analyzed using two dimensional field analysis based on the diffusion equation, employing either rectangular or polycentric grid structures. Such a field analysis allows us to visualize the complex vector potential and flux density distributions inside the unsaturated transformer operating under short-circuit conditions. One can calculate the eddy currents within conducting materials, such as copper and aluminum windings, from complex vector potential values. Short-circuit tests applied to low and high voltage windings allow us to calculate the eddy currents inside each winding and consequently their eddy-current losses. The frequency dependent AC winding resistance RAC as well as the per-unit eddy-current loss coefficient PEC-R are computed. These values are used to determine the derating of transformers via either the K-factor as proposed by Underwriters Laboratory, Inc., or via the harmonic loss factor FHL, as favored by IEEE and IEC. A new digital data

  7. Method for monitoring intertidal communities in a steep rocky shore: a combination of digital image technology and field operational strategy

    Directory of Open Access Journals (Sweden)

    Danuza Nogueira Moysés

    2007-03-01

    Full Text Available This paper introduces a method for temporal studies of steep rocky intertidal communities. It combines the use of digital image technology with field methodology, so that a wide area of the community can be sampled in a short time. Two current nondestructive percent cover estimation methods (visual estimation and point intersection were compared in terms of cost, operational advantages and data quality, with a proposed method for a sucessional study . The proposed method used sequential photos to sample multiple fixed vertical transects over time. Reproduction of the mid-intertidal transect over time was possible by overlaying temporal transects in an image editing program. This method was similar to the point intersection quadrat method used to estimate percent cover. Benefits included reduced time on field work, economic advantages and other advantages of using digital photography, such as recording. Temporal photography of transects provided measurements of recruitment, mortality and population growth, and made it possible to manufacture an animation of sucessional stages. We suggest that this is the best method for providing information and understanding on the process of succession and for monitoring benthic invertebrate intertidal communities on steep rocky shores.Este trabalho apresenta uma metodologia para estudos temporais de comunidades entre-marés de costões rochosos com acentuada inclinação, associando tecnologia de captura de imagens digitais com uma estrutura operacional de campo, permitindo a amostragem de ampla faixa da comunidade, em pouco tempo. Dois métodos tradicionais de estimativa de porcentagem de cobertura (estimativa visual e pontos de interseção foram usados para comparar a aplicabilidade do método proposto a um estudo de sucessão, quanto às vantagens econômicas, operacionais e qualidade dos dados obtidos. O método permite a amostragem temporal de múltiplos transectos verticais específicos, por meio de

  8. 表达登革病毒prM基因小干扰RNA的Vero细胞系的建立%Establishment of Vero Cell Lines with Expression of Small Interfering RNA Targeting Dengue Virus prM Gene

    Institute of Scientific and Technical Information of China (English)

    李磊; 吴新伟; 伍业健; 罗兰; 蒋力云; 杨霞

    2011-01-01

    prM蛋白是登革病毒膜蛋白M的前体,膜蛋白M对病毒的组装与成熟有重要作用,针对prM基因设计的小干扰RNA(siRNA)可短期抑制登革病毒复制.为了达到长期抑制登革病毒的效果,本研究构建了插入prM siRNA序列的重组慢病毒,利用流式细胞术分选以及杀稻瘟霉素抗性,筛选出稳定表达prM siRNA的非洲绿猴肾细胞(Vero细胞)系.经逆转录PCR及测序验证siRNA序列表达正确.Vero细胞中prM siRNA的表达率约为97.6%.当受到登革病毒攻击时,表达prM siRNA的Vero细胞能够明显抑制登革病毒prM基因的表达,并抑制登革病毒在Vero细胞中的复制.建立的Vero细胞系可用于RNA干扰防治登革病毒感染的进一步应用研究.%PrM is the precursor of a membrane protein M that plays an important role in the assembling and maturation of dengue virus. Small interfering RNA ( siRNA) targeted to prM gene can transiently inhibit the replication of dengue viruses. In order to establish persistent inhibitory effect, recombinant lentiviruses with prM siRNA sequence were constructed and produced in 293FT cells, then transfected into African green monkey kidney cells ( Vero cells). Vero cells stably expressing of prM siRNA were selected by blasticitin resistance and fluorescence activating cell sorter (FACS) sorting. The sequence of expressed siRNA was confirmed by reverse transcript PCR and DNA sequencing. The prM siRNA expression was detected in about 97. 6% of the obtained Vero cells. When exposed to dengue viruses, prM siRNA expression Vero cells showed significant suppression on prM protein expression, and inhibition on the replication of dengue viruses. These cell lines can be used for future studies of RNA interference on the protection of dengue virus infection.

  9. 40 CFR 63.8575 - What do I need to know about operation, maintenance, and monitoring plans?

    Science.gov (United States)

    2010-07-01

    ... SOURCE CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants for Clay Ceramics... unit such that the measurement is representative of control of the exhaust emissions (e.g., on or... quality assurance procedures consistent with the requirements in § 63.8(d). (10) Continuous monitoring...

  10. Wireless sensor and data transmission needs and technologies for patient monitoring in the operating room and intensive care unit.

    Science.gov (United States)

    Paksuniemi, M; Sorvoja, H; Alasaarela, E; Myllyla, R

    2005-01-01

    In the intensive care unit, or during anesthesia, patients are attached to monitors by cables. These cables obstruct nursing staff and hinder the patients from moving freely in the hospital. However, rapidly developing wireless technologies are expected to solve these problems. To this end, this study revealed problem areas in current patient monitoring and established the most important medical parameters to monitor. In addition, usable wireless techniques for short-range data transmission were explored and currently employed wireless applications in the hospital environment were studied. The most important parameters measured of the patient include blood pressures, electrocardiography, respiration rate, heart rate and temperature. Currently used wireless techniques in hospitals are based on the WMTS and WLAN standards. There are no viable solutions for short-range data transmission from patient sensors to patient monitors, but potentially usable techniques in the future are based on the WPAN standards. These techniques include Bluetooth, ZigBee and UWB. Other suitable techniques might be based on capacitive or inductive coupling. The establishing of wireless techniques depends on ensuring the reliability of data transmission, eliminating disturbance by other wireless devices, ensuring patient data security and patient safety, and lowering the power consumption and price.

  11. Applying monitoring, verification, and accounting techniques to a real-world, enhanced oil recovery operational CO2 leak

    Science.gov (United States)

    Wimmer, B.T.; Krapac, I.G.; Locke, R.; Iranmanesh, A.

    2011-01-01

    The use of carbon dioxide (CO2) for enhanced oil recovery (EOR) is being tested for oil fields in the Illinois Basin, USA. While this technology has shown promise for improving oil production, it has raised some issues about the safety of CO2 injection and storage. The Midwest Geological Sequestration Consortium (MGSC) organized a Monitoring, Verification, and Accounting (MVA) team to develop and deploy monitoring programs at three EOR sites in Illinois, Indiana, and Kentucky, USA. MVA goals include establishing baseline conditions to evaluate potential impacts from CO2 injection, demonstrating that project activities are protective of human health and the environment, and providing an accurate accounting of stored CO2. This paper focuses on the use of MVA techniques in monitoring a small CO2 leak from a supply line at an EOR facility under real-world conditions. The ability of shallow monitoring techniques to detect and quantify a CO2 leak under real-world conditions has been largely unproven. In July of 2009, a leak in the pipe supplying pressurized CO2 to an injection well was observed at an MGSC EOR site located in west-central Kentucky. Carbon dioxide was escaping from the supply pipe located approximately 1 m underground. The leak was discovered visually by site personnel and injection was halted immediately. At its largest extent, the hole created by the leak was approximately 1.9 m long by 1.7 m wide and 0.7 m deep in the land surface. This circumstance provided an excellent opportunity to evaluate the performance of several monitoring techniques including soil CO2 flux measurements, portable infrared gas analysis, thermal infrared imagery, and aerial hyperspectral imagery. Valuable experience was gained during this effort. Lessons learned included determining 1) hyperspectral imagery was not effective in detecting this relatively small, short-term CO2 leak, 2) even though injection was halted, the leak remained dynamic and presented a safety risk concern

  12. Web publishing of plant operation monitoring system based on SVG/AJAX/Internet%基于SVG/AJAX/Internet的电厂运行监视系统

    Institute of Scientific and Technical Information of China (English)

    胡冰; 章坚民; 马国梁; 方文道; 郭明泽

    2011-01-01

    为了解决电厂运行监视系统的运行状态和监视指标的实时性和便利性问题,提出了一种利用AJAX技术实现系统的Web发布方案,以SVG作为图形系统的Web发布和显示格式,采用以AJAX技术为核心的异步通信机制,有效解决了信息实时动态刷新问题.实际应用表明,采用该方法实现的热电厂监控系统具有节省网络带宽、减少传输时延、页面更新无闪烁的优点,操作人员可以很方便的通过Web浏览器了解热电厂机组的运行状态,有利于协调政府、电网公司、电厂三者不同关切和利益.%In order to solve the problems of the real-time and convenience of operation status and monitoring index of plant operation monitoring system, a method was presented for the Web publishing of monitoring system of power plant based on AJAX. SVG was used as the Web publishing and display format of graphics system. In order to solve the problem of information' s real-time dynamic refreshment, the AJAX was elected as the asynchronous communication mechanism. The application results show that this method has the advantages of saving network bandwidth, reducing transmission delay and flashed-free of page updates. Operation officers can easily learn the operation status of the power plant unit through Web browser. It's benefit for the coordination of government, grid state, power plant.

  13. 核磁共振设备运行监控系统的研制%Development of an Operation Monitoring System for Nuclear Magnetic Resonance Equipment

    Institute of Scientific and Technical Information of China (English)

    杨晓

    2016-01-01

    无人值守核磁共振设备若发生意外断电,会对设备造成一定损害。本文针对以上问题研制了核磁共振运行监控系统,系统采用AVR单片机对市电进行意外断电监测,通过GSM/GPRS模块向接收终端如固话、手机发送语音及短消息。应用结果表明,该系统能实时监控核磁共振设备供电情况,为设备安全运行发挥了重要作用,具有较高的使用价值。%Sudden power outage would cause great harm to the unattended nuclear magnetic resonance equipment. In view of this problem, an operation monitoring system for nuclear magnetic resonace was developed in this paper, which adopted AVR microcontroller to monitor the sudden power outage and sent SMS (Short Message Service) or voice information to terminals such as ifxed and mobile phones via the GSM/GPRS module. According to the results, the system realized real-time monitoring of the power supply of the nuclear magnetic resonance equipment and had played an important role in safe operation of the equipment, which was of great signiifcance in practice.

  14. Identification of Critical Operation Conditions of Industrial Gearboxes by 24/7 Monitoring of Oil Quality, Oil Aging, and Additive Consumption

    Science.gov (United States)

    Mauntz, M.; Peuser, J.

    2017-05-01

    The demand for wind energy grows at exponential rates. At the same time improving reliability, reduced operation and maintenance costs are the key priorities in wind tur-bine maintenance strategies [1]. This paper provides information about a novel online oil condition monitoring system to give a solution to the mentioned priorities. The presented sensor system enables damage prevention of the wind turbine gear-box by an advanced warning time of critical operation conditions and an enhanced oil exchange interval realized by a precise measurement of the electrical conductivity, the relative permittivity and the oil temperature. A new parameter, the WearSens® Index (WSi) is introduced. The mathematical model of the WSi combines all measured values and its gradients in one single parameter for a comprehensive monitoring to prevent wind turbines from damage. Furthermore, the WSi enables a long-term prognosis on the next oil change by 24/7 server data logging. Corrective procedures and/or maintenance can be carried out before actual damage occurs. First WSi results of an onshore wind turbine installation compared to traditional vibration monitoring are shown.

  15. Source Water Management for Disinfection By-Product Control using New York City's Operations Support Tool and On-Line Monitoring

    Science.gov (United States)

    Weiss, W. J.; Becker, W.; Schindler, S.

    2012-12-01

    The United States Environmental Protection Agency's 2006 Stage 2 Disinfectant / Disinfection Byproduct Rule (DBPR) for finished drinking waters is intended to reduce overall DBP levels by limiting the levels of total trihalomethanes (TTHM) and five of the haloacetic acids (HAA5). Under Stage 2, maximum contaminant levels (MCLs), 80 μg/L for TTHM and 60 μg/L for HAA5, are based on a locational running annual average for individual sites instead of as the system-wide quarterly running annual average of the Stage 1 DBPR. This means compliance will have to be met at sampling locations of peak TTHM and HAA5 concentrations rather than an average across the entire system. Compliance monitoring under the Stage 2 DBPR began on April 1, 2012. The New York City (NYC) Department of Environmental Protection (DEP) began evaluating potential impacts of the Stage 2 DBPR on NYC's unfiltered water supply in 2002 by monitoring TTHM and HAA5 levels at various locations throughout the distribution system. Initial monitoring indicated that HAA5 levels could be of concern in the future, with the potential to intermittently violate the Stage 2 DBPR at specific locations, particularly those with high water age. Because of the uncertainty regarding the long-term prospect for compliance, DEP evaluated alternatives to ensure compliance, including operational changes (reducing chlorine dose, changing flow configurations to minimize water age, altering pH, altering source water withdrawals); changing the residual disinfectant from free chlorine to chloramines; and engineered treatment alternatives. This paper will discuss the potential for using DEP's Operations Support Tool (OST) and enhanced reservoir monitoring to support optimization of source water withdrawals to minimize finished water DBP levels. The OST is a state-of-the-art decision support system (DSS) to provide computational and predictive support for water supply operations and planning. It incorporates a water supply system

  16. Development of a Turn-by-Turn Beam Position Monitoring System for Multiple Bunch Operation of the ATF Damping Ring

    CERN Document Server

    Burrows, P N; Kraljevic, N Blaskovic; Christian, G B; Davis, M R; Perry, C; Apsimon, R J; Constance, B; Gerbershagen, A; Resta-Lopez, J

    2012-01-01

    An FPGA-based monitoring system has been developed to study multi-bunch beam instabilities in the damping ring (DR) of the KEK Accelerator Test Facility (ATF). The system utilises a stripline beam position monitor (BPM) and single-stage down-mixing BPM processor. The system is designed to record the horizontal and/or vertical positions of up to three bunches in the DR with c. 150ns bunch spacing, or the head bunch of up to three trains in a multi-bunch mode with a bunch spacing of 5.6 ns. The FPGA firmware and data acquisition software allow the recording of turnby-turn data. An overview of the system and performance results will be presented.

  17. Control of Process Operations and Monitoring of Product Qualities through Generic Model-based Framework in Crystallization Processes

    DEFF Research Database (Denmark)

    Abdul Samad, Noor Asma Fazli Bin

    A generic and systematic model-based framework for the design of a process monitoring and control system to achieve the desired crystal size distribution (CSD) and crystal shape for a wide range of crystallization processes has been developed. This framework combines a generic multi......-dimensional to a twodimensional description; b) the systematic framework is used in a case study to design a monitoring and control (PAT) system for a potassium dichromate and KDP crystallization processes to achieve the desired target CSD respectively; and c) Based on the PAT system design in b), the application of uncertainty......-dimensional modelling framework, tools for design of set point profiles, for design of PAT (Process Analytical Technology) systems as well as option to perform the uncertainty and sensitivity analysis of the PAT system design. Through this framework, it is possible for a wide range of crystallization processes...

  18. RCRA and operational monitoring (ROM): Multi-year program plan and fiscal year 96 work plan. WBS 1.5.3, Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-09-01

    The RCRA & Operational Monitoring (ROM) Program Office manages the Hanford Site direct funded Resource Conservation and Recovery Act (RCRA) and Operational Monitoring under Work Breakdown Structure (WBS) 1.01.05.03. The ROM Program Office is included in Hanford Technical Services, a part of Projects & Site Services of Westinghouse Hanford Company (WHC). The 1996 Multi-Year Program Plan (MYPP) includes the Fiscal Year Work Plan (FYWP). The Multi-Year Program Plan takes its direction from the Westinghouse Planning Baseline Integration Organization. The MYPP provides both the near term, enhanced details and the long term, projected details for the Program Office to use as baseline Cost, Scope and Schedule. Change Control administered during the fiscal year is against the baseline provided by near term details of this document. The MYPP process has been developed by WHC to meet its internal planning and integration needs and complies with the requirements of the US Department of Energy, Richland Operations Office (RL) Long Range Planning Process Directive (RLID 5000.2). Westinghouse Hanford Company (WHC) has developed the multi-year planning process for programs to establish the technical, schedule and cost baselines for program and support activities under WHC`s scope of responsibility. The baseline information is developed by both WHC indirect funded support services organization, and direct funded programs in WHC. WHC Planning and Integration utilizes the information presented in the program specific MYPP and the Program Master Baseline Schedule (PMBS) to develop the Site-Wide Integrated Schedule.

  19. Consideration of modal structural properties with sensor grids and methods of Operational Modal Analysis. A contribution of state monitoring of great structures; Erfassung modaler Struktureigenschaften mit Sensornetzwerken und den Methoden der Operational Modal Analysis. Ein Beitrag zur Zustandsueberwachung grosser Strukturen

    Energy Technology Data Exchange (ETDEWEB)

    Friedmann, A.; Mayer, D.; Koch, M.; Kauba, M.; Melz, T. [Fraunhofer-Institut fuer Betriebsfestigkeit und Systemzuverlaessigkeit LBF, Darmstadt (Germany)

    2010-07-01

    A state monitoring of mechanical structures is possible based on the modal parameters natural frequency, self-oscillation form and modal damping. Beyond the damage recognition such a monitoring also can be used to the localization of damages. During the monitoring of large structures (such as blades or towers of wind power plants) problems arise with the instrumentation realization: However the execution of a unique data acquisition requires an expenditure which goes beyond logistic questions such as sensor assembly, grid connection and excitation. The presented solution covers two components whose combination can overcome the described problem definition. On the one hand a network of intelligent sensors will be used, on the other hand the received data are evaluated according to the methods of operational modal analysis. So the temporal development of the modal parameters can be supervised with a firmly installed sensor network based on the data received in the normal operation of the structure. The contribution under consideration contains a description of the Random Decrement Method used for the spectral estimation in the sensors. Subsequently, the function mode of the sensor network is presented from the data capture up to the modal dismantling with the help of a numeric system simulation. The realization of the sensor network at a mechanical, wind-excited test-structure is described. The results of the investigation of the test-structure with the sensor network are presented and compared with the results of conventional procedures. The innovation of the presented technology exists in the combination of known methods of random decrement and operational modal analysis with the possibilities of a network of intelligent sensors.

  20. Establishment of cell lines stably co-expressing Japanese encephalitis virus prM and E protein with a mutant in prM furin cleavage site%流行性乙型脑炎prM蛋白剪切位点突变的prM-E蛋白表达细胞系的建立

    Institute of Scientific and Technical Information of China (English)

    李业南; 陈振师; 步志高; 华荣虹

    2013-01-01

    In order to establish the BHK-21 cell lines stably co-expressing prM-E fusion protein of Japanese encephalitis virus (JEV) with a mutant furin site to disable the pre-peptide cleavage of prM, BHK-21 cells was transfected with the recombinant plasmid pCAG-JEV-prM(R89A)E, which was constructed by introducing a point mutation at the cleavage site of prM gene by PCR and cloned into eukaryotic vector pCAG-neo with E gene. Cells stably co-expressing prM-E fusion protein were selected in the present of G418 and identified by indirect immunofluorescence assay and western blot, In addition, the cells displaying high-level protein expression were purified through limiting dilution cloning. Eventfully, the results showed that the cell line was able to express the intact prM of prM-E fusion protein. The established cell line would provide a basis for further study the effect of the cleavage event on mature mechanism of JEV and the development of JEV subunit vaccine.%为建立稳定共表达乙型脑炎病-毒(JEV)完整M前体蛋白(prM)和E蛋白的BHK-21细胞系,本研究在prM蛋白furin蛋白酶剪切位点编码基因中引入突变,将突变后的prM基因克隆于质粒中构建重组表达质粒pCAG-JEV-prM(R89A)E.将重组质粒转染BHK-21细胞,转染48 h后细胞用含G418的选择性培养基选择培养,进一步经细胞克隆纯化制备表达剪切位点突变的JEV prM-E蛋白的稳定细胞系.经IFA和western blot鉴定表明,该细胞系能表达JEV prM与E蛋白,所表达的prM蛋白未发生剪切;细胞经多次传代后仍能够稳定地共表达prM与E蛋白.该细胞系的建立为研究prM蛋白剪切对JEV粒子形成的影响以及亚单位疫苗的制备奠定了基础.

  1. Post-Closure Monitoring Report for Corrective Action Unit 339: Area 12 Fleet Operations Steam Cleaning Discharge Area Nevada Test Site, Nevada

    Energy Technology Data Exchange (ETDEWEB)

    A. T. Urbon

    2001-08-01

    The Area 12 Fleet Operations Steam Cleaning site is located in the southeast portion of the Area 12 Camp at the Nevada Test Site (Figure 1). This site is identified in the Federal Facility Agreement and Consent Order (FFACO, 1996) as Corrective Action Site (CAS) 12-19-01 and is the only CAS assigned to Corrective Action Unit (CAU) 339. Post-closure sampling and inspection of the site were completed on March 23, 2001. Because of questionable representativeness and precision of the results, the site was resampled on June 12, 2001. Post-closure monitoring activities were scheduled biennially (every two years) in the Post-Closure Monitoring Plan provided in the December 1997 Closure Report for CAU 339: Area 12 Fleet Operations Steam Cleaning Discharge Area, Nevada Test Site (U.S. Department of Energy, Nevada Operations Office [DOE/NV], 1997). If after six years the rate of degradation appears to be so slow that the greatest concentration of total petroleum hydrocarbons (TPH) present at the site would not decay within 30 years of the site closure, the site will be reevaluated with consideration to enriching the impacted soil at the site to enhance the degradation process. A baseline for the site was established by sampling in 1997. Based on the recommendations from the 1999 post-closure monitoring report, samples were collected in 2000, earlier than originally proposed, because the 1999 sample results did not provide the expected decrease in TPH concentrations at the site. Sampling results from 2000 revealed favorable conditions for natural degradation at the CAU 339 site, but because of differing sample methods and heterogeneity of the soil, the data results from 2000 were not directly correlated with previous results. Post-closure monitoring activities for 2001 consisted of the following: Soil sample collection from three undisturbed plots (Plots A, B, and C, Figure 2); Sample analysis for TPH as oil and bio-characterization parameters (Comparative Enumeration Assay

  2. Analytical results and effective dose estimation of the operational Environmental Monitoring Program for the radioactive waste repository in Abadia de Goias from 1998 to 2008

    Energy Technology Data Exchange (ETDEWEB)

    Ribeiro, Edison, E-mail: edison@cnen.gov.b [Centro Regional de Ciencias Nucleares do Centro-Oeste, Comissao Nacional de Energia Nuclear- Br 060 km 174, 5-Abadia de Goias- Goias, CEP 75345-000 (Brazil); Tauhata, Luiz, E-mail: tauhata@ird.gov.b [Instituto de Radioprotecao e Dosimetria, Comissao Nacional de Energia Nuclear, Recreio dos Bandeirantes, Rio de Janeiro, RJ, CEP 22780-160 (Brazil); Eugenia dos Santos, Eliane, E-mail: esantos@cnen.gov.b [Centro Regional de Ciencias Nucleares do Centro-Oeste, Comissao Nacional de Energia Nuclear- Br 060 km 174, 5-Abadia de Goias- Goias, CEP 75345-000 (Brazil); Silveira Correa, Rosangela da, E-mail: rcorrea@cnen.gov.b [Centro Regional de Ciencias Nucleares do Centro-Oeste, Comissao Nacional de Energia Nuclear- Br 060 km 174, 5-Abadia de Goias- Goias, CEP 75345-000 (Brazil)

    2011-02-15

    This paper presents the results of the Environmental Monitoring Program for the Radioactive waste repository of Abadia de Goias, which was originated from the accident of Goiania, conducted by the Regional Center of Nuclear Sciences (CRCN-CO) of the National Commission on Nuclear Energy (CNEN), from 1998 to 2008. The results are related to the determination of {sup 137}Cs activity per unit of mass or volume of samples from surface water, ground water, depth sediments of the river, soil and vegetation, and also the air-kerma rate estimation for gamma exposure in the monitored site. In the phase of operational Environmental Monitoring Program, the values of the geometric mean and standard deviation obtained for {sup 137}Cs activity per unit of mass or volume in the analyzed samples were (0.08 {+-} 1.16) Bq.L{sup -1} for surface and underground water, (0.22 {+-} 2.79) Bq.kg{sup -1} for soil, and (0.19 {+-} 2.72) Bq.kg{sup -1} for sediment, and (0.19 {+-} 2.30) Bq.kg{sup -1} for vegetation. These results were similar to the values of the pre-operational Environmental Monitoring Program. With these data, estimations for effective dose were evaluated for public individuals in the neighborhood of the waste repository, considering the main possible way of exposure of this population group. The annual effective dose obtained from the analysis of these results were lower than 0.3 mSv.y{sup -1}, which is the limit established by CNEN for environmental impact in the public individuals indicating that the facility is operating safely, without any radiological impact to the surrounding environment. - Research highlights: {yields} A stolen capsule of Cesium 137 was opened in the city of Goiania, generating some 6000 tons of debris which were stored in the Repository area built for this purpose. {yields} The activity of cesium 137 of the surface water, underground water, depth sediments of river, soil, vegetation, and air, inside and surround the Repository area. {yields

  3. Sequence-dependent upstream DNA-RNA polymerase interactions in the open complex with lambdaPR and lambdaPRM promoters and implications for the mechanism of promoter interference.

    Science.gov (United States)

    Mangiarotti, Laura; Cellai, Sara; Ross, Wilma; Bustamante, Carlos; Rivetti, Claudio

    2009-01-23

    Upstream interactions of Escherichia coli RNA polymerase (RNAP) in an open promoter complex (RPo) formed at the P(R) and P(RM) promoters of bacteriophage lambda have been studied by atomic force microscopy. We demonstrate that the previously described 30-nm DNA compaction observed upon RPo formation at P(R) [Rivetti, C., Guthold, M. & Bustamante, C. (1999). Wrapping of DNA around the E. coli RNA polymerase open promoter complex. EMBO J., 18, 4464-4475.] is a consequence of the specific interaction of the RNAP with two AT-rich sequence determinants positioned from -36 to -59 and from -80 to -100. Likewise, RPos formed at P(RM) showed a specific contact between RNAP and the upstream DNA sequence. We further demonstrate that this interaction, which results in DNA wrapping against the polymerase surface, is mediated by the C-terminal domains of alpha-subunits (carboxy-terminal domain). Substitution of these AT-rich sequences with heterologous DNA reduces DNA wrapping but has only a small effect on the activity of the P(R) promoter. We find, however, that the frequency of DNA templates with both P(R) and P(RM) occupied by an RNAP significantly increases upon loss of DNA wrapping. These results suggest that alpha carboxy-terminal domain interactions with upstream DNA can also play a role in regulating the expression of closely spaced promoters. Finally, a model for a possible mechanism of promoter interference between P(R) and P(RM) is proposed.

  4. Implementation of an Automatic System for the Monitoring of Start-up and Operating Regimes of the Cooling Water Installations of a Hydro Generator

    Directory of Open Access Journals (Sweden)

    Ioan Pădureanu

    2015-07-01

    Full Text Available The safe operation of a hydro generator depends on its thermal regime, the basic conditions being that the temperature in the stator winding fall within the limits of the insulation class. As the losses in copper depend on the square current in the stator winding, it is necessary that the cooling water debit should be adapted to the values of these losses, so that the winding temperature falls within the range of the values prescribed in the specifications. This paper presents an efficient solution of commanding and monitoring the water cooling installations of two high-power hydro generators.

  5. 40 CFR 63.3557 - What are the requirements for continuous parameter monitoring system installation, operation, and...

    Science.gov (United States)

    2010-07-01

    ..., maintain, and operate a flow indicator that takes a reading at least once every 15 minutes. The flow indicator shall be installed at the entrance to any bypass line. (2) Secure the bypass line valve in the nondiverting position with a car-seal or lock-and-key type configuration. A visual inspection of the seal or...

  6. 40 CFR Table 3 to Subpart Ec of... - Operating Parameters To Be Monitored and Minimum Measurement and Recording Frequencies

    Science.gov (United States)

    2010-07-01

    ... flow rate Hourly 1×hour ✔ ✔ Minimum pressure drop across the wet scrubber or minimum horsepower or... scrubber followed by fabric filter Wet scrubber Dry scrubber followed by fabric filter and wet scrubber Maximum operating parameters: Maximum charge rate Continuous 1×hour ✔ ✔ ✔ Maximum fabric filter...

  7. 40 CFR Table 3 to Subpart Hhh of... - Operating Parameters To Be Monitored and Minimum Measurement and Recording Frequencies

    Science.gov (United States)

    2010-07-01

    ... mercury (Hg) sorbent flow rate Hourly Once per hour ✔ ✔ Minimum pressure drop across the wet scrubber or... rural HMIWI HMIWI a with dry scrubber followed by fabric filter HMIWI a with wet scrubber HMIWI a with dry scrubber followed by fabric filter and wet scrubber Maximum operating parameters: Maximum...

  8. Large-scale multiplex absolute protein quantification of drug-metabolizing enzymes and transporters in human intestine, liver, and kidney microsomes by SWATH-MS: Comparison with MRM/SRM and HR-MRM/PRM.

    Science.gov (United States)

    Nakamura, Kenji; Hirayama-Kurogi, Mio; Ito, Shingo; Kuno, Takuya; Yoneyama, Toshihiro; Obuchi, Wataru; Terasaki, Tetsuya; Ohtsuki, Sumio

    2016-08-01

    The purpose of the present study was to examine simultaneously the absolute protein amounts of 152 membrane and membrane-associated proteins, including 30 metabolizing enzymes and 107 transporters, in pooled microsomal fractions of human liver, kidney, and intestine by means of SWATH-MS with stable isotope-labeled internal standard peptides, and to compare the results with those obtained by MRM/SRM and high resolution (HR)-MRM/PRM. The protein expression levels of 27 metabolizing enzymes, 54 transporters, and six other membrane proteins were quantitated by SWATH-MS; other targets were below the lower limits of quantitation. Most of the values determined by SWATH-MS differed by less than 50% from those obtained by MRM/SRM or HR-MRM/PRM. Various metabolizing enzymes were expressed in liver microsomes more abundantly than in other microsomes. Ten, 13, and eight transporters listed as important for drugs by International Transporter Consortium were quantified in liver, kidney, and intestinal microsomes, respectively. Our results indicate that SWATH-MS enables large-scale multiplex absolute protein quantification while retaining similar quantitative capability to MRM/SRM or HR-MRM/PRM. SWATH-MS is expected to be useful methodology in the context of drug development for elucidating the molecular mechanisms of drug absorption, metabolism, and excretion in the human body based on protein profile information.

  9. A new magnetotelluric monitoring network operating in Agri Valley (Southern Italy: study of stability of apparent resistivity estimates

    Directory of Open Access Journals (Sweden)

    L. Telesca

    2008-06-01

    Full Text Available Variations detected in geophysical, especially electromagnetic, parameters in seismic active areas have been sometimes attributed to modifications of the stress field. Among the different geophysical methods, magnetotellurics (MT could be one of the most effective because it allows us to explore down to seismogenic depths. Continuous MT recording could allow us to evaluate whether possible variations are significantly correlated with the seismic activity of investigated area. To assess the significance of such observations we must be able to say how well an apparent resistivity curve should be reproduced when measurements are repeated at a later time. To do this properly it is essential to know that the estimated error bars accurately represent the true uncertainties in comparing the transfer functions. In this work we will show the preliminary results obtained from the analysis of the data coming from the new MT monitoring network installed in Agri Valley. This analysis gives us the possibility: i to better study the temporal stability of the signals, ii to better discriminate the noise affecting the measures by remote reference estimation. The performed analysis disclosed a relatively low degree of noise in the investigated area, which is a promising condition for monitoring.

  10. Post-exercise contractility, diastolic function, and pressure: Operator-independent sensor-based intelligent monitoring for heart failure telemedicine

    Directory of Open Access Journals (Sweden)

    Giannoni Massimo

    2009-05-01

    Full Text Available Abstract Background New sensors for intelligent remote monitoring of the heart should be developed. Recently, a cutaneous force-frequency relation recording system has been validated based on heart sound amplitude and timing variations at increasing heart rates. Aim To assess sensor-based post-exercise contractility, diastolic function and pressure in normal and diseased hearts as a model of a wireless telemedicine system. Methods We enrolled 150 patients and 22 controls referred for exercise-stress echocardiography, age 55 ± 18 years. The sensor was attached in the precordial region by an ECG electrode. Stress and recovery contractility were derived by first heart sound amplitude vibration changes; diastolic times were acquired continuously. Systemic pressure changes were quantitatively documented by second heart sound recording. Results Interpretable sensor recordings were obtained in all patients (feasibility = 100%. Post-exercise contractility overshoot (defined as increase > 10% of recovery contractility vs exercise value was more frequent in patients than controls (27% vs 8%, p 1 in 20 patients and in none of the controls (p 1 in only 3 patients (p Conclusion Post-exercise contractility, diastolic time and pressure changes can be continuously measured by a cutaneous sensor. Heart disease affects not only exercise systolic performance, but also post-exercise recovery, diastolic time intervals and blood pressure changes – in our study, all of these were monitored by a non-invasive wearable sensor.

  11. An Operational In Situ Soil Moisture & Soil Temperature Monitoring Network for West Wales, UK: The WSMN Network

    Directory of Open Access Journals (Sweden)

    George P. Petropoulos

    2017-06-01

    Full Text Available This paper describes a soil moisture dataset that has been collecting ground measurements of soil moisture, soil temperature and related parameters for west Wales, United Kingdom. Already acquired in situ data have been archived to the autonomous Wales Soil Moisture Network (WSMN since its foundation in July 2011. The sites from which measurements are being collected represent a range of conditions typical of the Welsh environment, with climate ranging from oceanic to temperate and a range of the most typical land use/cover types found in Wales. At present, WSMN consists of a total of nine monitoring sites across the area with a concentration of sites in three sub-areas around the region of Aberystwyth located in Mid-Wales. The dataset of composed of 0–5 (or 0–10 cm soil moisture, soil temperature, precipitation, and other ancillary data. WSMN data are provided openly to the public via the International Soil Moisture Network (ISMN platform. At present, WSMN is also rapidly expanding thanks to funding obtained recently which allows more monitoring sites to be added to the network to the wider community interested in using its data.

  12. A summary of the test procedures and operational details of an ocean dumping pollution monitoring experiment conducted 7 October 1976

    Science.gov (United States)

    Hypes, W. D.; Wallace, J. W.; Gurganus, E. A.

    1977-01-01

    A remote sensor experiment was conducted at a sewage sludge dump site off the Delaware/Maryland coast. Two aircraft serving as remote sensor platforms flew over the dump site during a sludge dump. One aircraft carried a multispectral scanner and the other aircraft carried a rapid scanning spectrometer. Data from sea-truth stations were collected concurrent with overpasses of the aircraft. All sensors were operational and produced good digital data.

  13. PRM理论在医院体检档案管理中的应用研究%Application of PRM theory on management of physical examination archives

    Institute of Scientific and Technical Information of China (English)

    林婕; 陈昱方

    2008-01-01

    由于新形势下医院体检档案管理模式的转变,我院体检中心在档案管理研究和实践工作中引进了国际先进的病人关系管理(Patient,Relationship Management,PRM)理论,建立并施行现代化体检档案管理.本文通过介绍PRM理论与PRM体检档案概念,讨论PRM体检档案的内容和特点,以及我院将PRM理论导人体检档案管理的经验,论证了PRM在充份掌握群众健康体检需求、降低医疗成本、维护服务对象忠诚度和扩大业务基础方面的作用.

  14. Serotype-specific anti-Dengue virus NS1 mouse antibodies cross-react with prM and are potentially involved in virus production.

    Science.gov (United States)

    Masrinoul, Promsin; Omokoko, Magot Diata; Pambudi, Sabar; Ikuta, Kazuyoshi; Kurosu, Takeshi

    2013-08-01

    Dengue virus (DENV) infection induces a strong B-cell immune response against the viral nonstructural protein 1 (NS1). Anti-NS1 antibodies (Abs) may affect virus production because they coexist with the virus in the patients' blood. The present study examined whether ten mouse monoclonal antibodies (MAbs) raised against NS1 affected production of the DENV-2. Three MAbs, 4C2, 4G11, and 4E5, showed weak neutralizing activity in a focus reduction assay. In addition, two serotype-specific MAbs, 4C2 and 4G11, protected suckling mice from lethal infection with DENV-2. An immunoprecipitation assay with DENV-2 showed that these MAbs, which were specific for the NS1 of DENV-4 and DENV-1, cross-reacted with the DENV-2 pre-membrane (prM) protein, but not with DENV-2 NS1. Interestingly, high concentrations of MAb 4G11 showed antibody-dependent enhancement of DENV-2 infection in human monocyte THP-1 cells. Taken together, these observations suggest that serotype-specific anti-NS1 MAbs are potentially involved in virus production.

  15. The vaccine efficacy of recombinant duck enteritis virus expressing secreted E with or without PrM proteins of duck tembusu virus.

    Science.gov (United States)

    Chen, Pucheng; Liu, Jinxiong; Jiang, Yongping; Zhao, Yuhui; Li, Qimeng; Wu, Li; He, Xijun; Chen, Hualan

    2014-09-15

    A newly emerged tembusu virus that causes egg-drop has been affecting ducks in China since 2010. Currently, no vaccine is available for this disease. A live attenuated duck enteritis virus (DEV; a herpesvirus) vaccine has been used routinely to control lethal DEV in ducks since the 1960s. Here, we constructed two recombinant DEVs by transfecting overlapping fosmid DNAs. One virus, rDEV-TE, expresses the truncated form of the envelope glycoprotein (TE) of duck tembusu virus (DTMUV), and the other virus, rDEV-PrM/TE, expresses both the TE and pre-membrane proteins (PrM). Animal study demonstrated that both recombinant viruses induced measurable anti-DTMUV neutralizing antibodies in ducks. After two doses of recombinant virus, rDEV-PrM/TE completely protected ducks from DTMUV challenge, whereas rDEV-TE only conferred partial protection. These results demonstrate that recombinant DEV expressing the TE and pre-membrane proteins is protective and can serve as a potential candidate vaccine to prevent DTMUV infection in ducks.

  16. Bone Health Monitoring in Astronauts: Recommended Use of Quantitative Computed Tomography [QCT] for Clinical and Operational Decisions

    Science.gov (United States)

    Sibonga, J. D.; Truskowski, P.

    2010-01-01

    This slide presentation reviews the concerns that astronauts in long duration flights might have a greater risk of bone fracture as they age than the general population. A panel of experts was convened to review the information and recommend mechanisms to monitor the health of bones in astronauts. The use of Quantitative Computed Tomography (QCT) scans for risk surveillance to detect the clinical trigger and to inform countermeasure evaluation is reviewed. An added benefit of QCT is that it facilitates an individualized estimation of bone strength by Finite Element Modeling (FEM), that can inform approaches for bone rehabilitation. The use of FEM is reviewed as a process that arrives at a composite number to estimate bone strength, because it integrates multiple factors.

  17. Design and operation of a 2-D thin-film semiconductor neutron detector array for use as a beamport monitor

    Energy Technology Data Exchange (ETDEWEB)

    Unruh, Troy C.; Bellinger, Steven L. [SMART Laboratory, Kansas State University, Mechanical and Nuclear Engineering Department, Manhattan, KS 66506 (United States); Huddleston, David E. [Electronics Design Laboratory, Kansas State University, Manhattan, KS 66506 (United States); McNeil, Walter J.; Patterson, Eric [SMART Laboratory, Kansas State University, Mechanical and Nuclear Engineering Department, Manhattan, KS 66506 (United States); Sobering, Tim J. [Electronics Design Laboratory, Kansas State University, Manhattan, KS 66506 (United States); McGregor, Douglas S. [SMART Laboratory, Kansas State University, Mechanical and Nuclear Engineering Department, Manhattan, KS 66506 (United States)], E-mail: mcgregor@ksu.edu

    2009-06-01

    Silicon-based diodes coated with a thin film of neutron reactive materials have been shown to produce excellent low-efficiency neutron detectors. This work employs the same technology, but groups 25 equally sized and spaced diodes on a single 29 mm by 29 mm substrate. A 5x5 array was fabricated and coated with a thin film of {sup 6}LiF for use as a low-efficiency neutron beam monitor. The 5x5 neutron detector array is coupled to an array of amplifiers, allowing the response to be interpreted using a LabVIEW FPGA. The 5x5 array has been characterized in a diffracted neutron beam. This work is a part of on-going research to develop various designs of high- and low-efficiency semiconductor neutron detectors.

  18. Development and validation of an automated operational modal analysis algorithm for vibration-based monitoring and tensile load estimation

    Science.gov (United States)

    Rainieri, Carlo; Fabbrocino, Giovanni

    2015-08-01

    In the last few decades large research efforts have been devoted to the development of methods for automated detection of damage and degradation phenomena at an early stage. Modal-based damage detection techniques are well-established methods, whose effectiveness for Level 1 (existence) and Level 2 (location) damage detection is demonstrated by several studies. The indirect estimation of tensile loads in cables and tie-rods is another attractive application of vibration measurements. It provides interesting opportunities for cheap and fast quality checks in the construction phase, as well as for safety evaluations and structural maintenance over the structure lifespan. However, the lack of automated modal identification and tracking procedures has been for long a relevant drawback to the extensive application of the above-mentioned techniques in the engineering practice. An increasing number of field applications of modal-based structural health and performance assessment are appearing after the development of several automated output-only modal identification procedures in the last few years. Nevertheless, additional efforts are still needed to enhance the robustness of automated modal identification algorithms, control the computational efforts and improve the reliability of modal parameter estimates (in particular, damping). This paper deals with an original algorithm for automated output-only modal parameter estimation. Particular emphasis is given to the extensive validation of the algorithm based on simulated and real datasets in view of continuous monitoring applications. The results point out that the algorithm is fairly robust and demonstrate its ability to provide accurate and precise estimates of the modal parameters, including damping ratios. As a result, it has been used to develop systems for vibration-based estimation of tensile loads in cables and tie-rods. Promising results have been achieved for non-destructive testing as well as continuous

  19. 大运行体系下电网监视成效探索%Exploring the Effectiveness in Improving the Network Monitoring Under the Operating System

    Institute of Scientific and Technical Information of China (English)

    王小仲; 王悦; 黄志华; 刘莹; 沈竹

    2014-01-01

    Through regulating reporting process of the abnormal information,and making full use of protec-tion and fault information management system,recording system,remote browsing and other advanced applica-tion functions,we effectively enhance the monitoring information of defect discovery rate,fault processing time rate,fault load transfer rate scheduling monitoring indicators,and improve work efficiency and operation level dispatch supervisory personnel to provide fast and accurate technical support to the power grid and equipment fault,defect elimination and to ensure the safe and stable operation of power grid.%通过规范异常信息上报流程和充分利用保护信息管理系统、故障录波系统、变电站远程浏览等高级应用功能,有效提升监控信息缺陷发现率、电网故障处理及时率、电网故障负荷转移率等调度监控指标,提高调度监控人员的工作效率及运维水平,为电网及设备故障、缺陷消除提供快速准确的技术支持,保障电网安全稳定运行。

  20. Measuring laser power as a force: a new paradigm to accurately monitor optical power during laser-based machining operations

    Science.gov (United States)

    Williams, Paul; Simonds, Brian; Sowards, Jeffrey; Hadler, Joshua

    2016-03-01

    In laser manufacturing operations, accurate measurement of laser power is important for product quality, operational repeatability, and process validation. Accurate real-time measurement of high-power lasers, however, is difficult. Typical thermal power meters must absorb all the laser power in order to measure it. This constrains power meters to be large, slow and exclusive (that is, the laser cannot be used for its intended purpose during the measurement). To address these limitations, we have developed a different paradigm in laser power measurement where the power is not measured according to its thermal equivalent but rather by measuring the laser beam's momentum (radiation pressure). Very simply, light reflecting from a mirror imparts a small force perpendicular to the mirror which is proportional to the optical power. By mounting a high-reflectivity mirror on a high-sensitivity force transducer (scale), we are able to measure laser power in the range of tens of watts up to ~ 100 kW. The critical parameters for such a device are mirror reflectivity, angle of incidence, and scale sensitivity and accuracy. We will describe our experimental characterization of a radiation-pressure-based optical power meter. We have tested it for modulated and CW laser powers up to 92 kW in the laboratory and up to 20 kW in an experimental laser welding booth. We will describe present accuracy, temporal response, sources of measurement uncertainty, and hurdles which must be overcome to have an accurate power meter capable of routine operation as a turning mirror within a laser delivery head.