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Sample records for monitor output potential

  1. Cardiac output monitoring

    Directory of Open Access Journals (Sweden)

    Mathews Lailu

    2008-01-01

    Full Text Available Minimally invasive and non-invasive methods of estimation of cardiac output (CO were developed to overcome the limitations of invasive nature of pulmonary artery catheterization (PAC and direct Fick method used for the measurement of stroke volume (SV. The important minimally invasive techniques available are: oesophageal Doppler monitoring (ODM, the derivative Fick method (using partial carbon dioxide (CO 2 breathing, transpulmonary thermodilution, lithium indicator dilution, pulse contour and pulse power analysis. Impedance cardiography is probably the only non-invasive technique in true sense. It provides information about haemodynamic status without the risk, cost and skill associated with the other invasive or minimally invasive techniques. It is important to understand what is really being measured and what assumptions and calculations have been incorporated with respect to a monitoring device. Understanding the basic principles of the above techniques as well as their advantages and limitations may be useful. In addition, the clinical validation of new techniques is necessary to convince that these new tools provide reliable measurements. In this review the physics behind the working of ODM, partial CO 2 breathing, transpulmonary thermodilution and lithium dilution techniques are dealt with. The physical and the physiological aspects underlying the pulse contour and pulse power analyses, various pulse contour techniques, their development, advantages and limitations are also covered. The principle of thoracic bioimpedance along with computation of CO from changes in thoracic impedance is explained. The purpose of the review is to help us minimize the dogmatic nature of practice favouring one technique or the other.

  2. Cardiac output monitoring

    NARCIS (Netherlands)

    de Waal, Eric. E. C.; Wappler, Frank; Buhre, Wolfgang F.

    2009-01-01

    Purpose of review The primary goal of hemodynamic therapy is the prevention of inadequate tissue perfusion and inadequate oxygenation. Advanced cardiovascular monitoring is a prerequisite to optimize hemodynamic treatment in critically ill patients prone to cardiocirculatory failure. The most ideal

  3. IR-images of PV-modules with potential induced degradation (PID) correlated to monitored string power output

    Science.gov (United States)

    Buerhop, Claudia; Pickel, Tobias; Blumberg, Tiberius; Adams, Jens; Wrana, Simon; Dalsass, Manuel; Zetzmann, Cornelia; Camus, Christian; Hauch, Jens; Brabec, Christoph J.

    2016-09-01

    Many PV-plants suffer from potential induced degradation (PID) which causes severe power reduction of installed PVmodules. Fast and reliable methods to detect PID and evaluate the impact on the module performance are gaining importance. Drone-assisted IR-inspection is a suitable method. PID affected modules are detected by their characteristic IR-fingerprint, modules with differing number of slightly heated cells occur more frequently at the negative string end. These modules show a degraded IV-curve, lowered Voc and Isc, and electroluminescence (EL)-images with suspicious, dark cells. Also, the measured string power is reduced. For a first quantitative data evaluation the suspicious cell are counted in the IR-images and correlated with the module power. A linear decrease of the module power with increasing number of suspicious cells results. A correlation function for estimating the module power was deduced, which has a mean deviation of less than 7%. This correlation function allows an acceptable approximation of the string power.

  4. A study of potential output and output gap in the Czech Republic

    Directory of Open Access Journals (Sweden)

    Václav Adamec

    2012-01-01

    Full Text Available Analysis of economic cycle is of enormous importance for monitoring economic output and explaining price and wage inflation. It provides essential information for shaping economic and monetary policy of central authorities. Several methods are currently available to estimate potential output and output gap. In the current study, methods of Hodrick-Prescott filter and Cobb-Douglas production function were implemented to estimate potential output, which cannot be empirically observed. For the purpose of comparing the above methods, quarterly and annual time series of real GDP, labour and gross fixed capital starting in 1996 were used for estimation of the output gap. Relative contributions of labour, fixed capital formation and technology improvement factor towards growth of potential output were quantified for the studied series. The Cobb-Douglas production function appears to be superior to Hodrick-Prescott filter in providing quality estimates of potential output. Hodrick-Prescott filter allows estimation of potential output; nevertheless, it fails to identify components of cyclic behaviour of economic activity. Cobb-Douglas production function describes level of potential product assuming average utilization of production factors. A detailed analysis of components of economic growth in the observed period is provided.

  5. Newer methods of cardiac output monitoring

    Institute of Scientific and Technical Information of China (English)

    Yatin; Mehta; Dheeraj; Arora

    2014-01-01

    Cardiac output(CO) is the volume of blood ejected by each ventricle per minute and is the product of stroke volume and heart rate. CO can thus be manipulated by alteration in heart rate or rhythm, preload, contractility and afterload. Moreover it gives important information about tissue perfusion and oxygen delivery. CO can be measured by various methods and thermodilution method using pulmonary artery catheter(PAC) is till date considered as gold standard method. Complications associated with PAC led to development of newer methods which are minimally or non-invasive. Newer methods fulfil other properties like continuous and reproducible reading, cost effective, reliable during various physiological states and have fast response time. These methods are validated against the gold standard with good level agreement. In this review we have discussed various newer methods of CO monitoring and their effectiveness in clinical use.

  6. Non-invasive cardiac output monitoring in neonates using bioreactance: a comparison with echocardiography.

    LENUS (Irish Health Repository)

    Weisz, Dany E

    2012-01-01

    Non-invasive cardiac output monitoring is a potentially useful clinical tool in the neonatal setting. Our aim was to evaluate a new method of non-invasive continuous cardiac output (CO) measurement (NICOM™) based on the principle of bioreactance in neonates.

  7. Mini invasive hemodynamic monitoring: from arterial pressure to cardiac output

    OpenAIRE

    Della Rocca, Giorgio; Cecconi, Maurizio; Costa, Maria Gabriella

    2008-01-01

    To evaluate the Cardiac Output (CO) the standard invasive pulmonary artery catheter (PAC) is considered today the gold standard. The major criticism to the PAC is that its level of invasiveness is not supported by an improvement in patient's outcome. The interest to lesser and lesser invasive techniques is high. Therefore, the alternative techniques have been recently developed.Cardiac Output can be monitored continuously by different devices that analyze the arterial waveform to track change...

  8. The novel application of Benford's second order analysis for monitoring radiation output in interventional radiology.

    Science.gov (United States)

    Cournane, S; Sheehy, N; Cooke, J

    2014-06-01

    Benford's law is an empirical observation which predicts the expected frequency of digits in naturally occurring datasets spanning multiple orders of magnitude, with the law having been most successfully applied as an audit tool in accountancy. This study investigated the sensitivity of the technique in identifying system output changes using simulated changes in interventional radiology Dose-Area-Product (DAP) data, with any deviations from Benford's distribution identified using z-statistics. The radiation output for interventional radiology X-ray equipment is monitored annually during quality control testing; however, for a considerable portion of the year an increased output of the system, potentially caused by engineering adjustments or spontaneous system faults may go unnoticed, leading to a potential increase in the radiation dose to patients. In normal operation recorded examination radiation outputs vary over multiple orders of magnitude rendering the application of normal statistics ineffective for detecting systematic changes in the output. In this work, the annual DAP datasets complied with Benford's first order law for first, second and combinations of the first and second digits. Further, a continuous 'rolling' second order technique was devised for trending simulated changes over shorter timescales. This distribution analysis, the first employment of the method for radiation output trending, detected significant changes simulated on the original data, proving the technique useful in this case. The potential is demonstrated for implementation of this novel analysis for monitoring and identifying change in suitable datasets for the purpose of system process control.

  9. System estimates of potential output and the NAIRU

    OpenAIRE

    1999-01-01

    This paper proposes a new approach for estimating potential output and the NAIRU. The methodology models these key unobservable economic variables as latent stochastic trends within a trivariate system of observables comprising information on unemployment, GDP, and inflation. Identification is achieved through the use of a standard version of Okun's law and a Phillips curve. The performance of the procedure is investigated using Swedish quarterly data covering the time period 1970:1-1996:3.

  10. Memory for Remembered Events: An Assessment of Output Monitoring in Free Recall

    Science.gov (United States)

    Gardiner, John M.; Klee, Hilary

    1976-01-01

    A study is reported describing an output-monitoring phenomenon in free recall and establishing that subjects have accurate knowledge concerning their previous output performance. Implications with respect to other known memory phenomena are discussed. (Author/RM)

  11. Estimation of Potential GDP and output Gap. Comparative Perspective

    Directory of Open Access Journals (Sweden)

    Dorin Măntescu

    2014-08-01

    Full Text Available The purpose of the analysis is to assess the impact of the crisis on the potential output and output gaps, to study their evolution by using a comparative approach for a sample of EU countries that were in majority included recently in financial assistance and macroeconomic adjustment programmes. The potential GDP growth rates calculated using the Cobb Douglas production function and Hodrick-Prescott methodology, decelerated substantially across the board in the countries studied once the international economic and financial crisis hit, recording even negative rates of growth in Cyprus, Greece, Portugal, Italy and Spain. In addition to the specific factors that characterise each country, there is a series of common features that will affect the developments of the potential GDP on a long-term basis, such as the increase of global risk aversion correlated with the reduction of the banking exposures, the slow economic recovery in the EU, and last but not least the incoming ageing process, which will exert an additional negative impact on the growth potential of the EU member states. The article makes a series of economic policy recommendations to promote key measures aiming to increase the flexibility of the goods, services, and labour markets, to improve the prioritisation of public expenditures especially capital spending, and to improve the management of the public assets including real estate and public buildings by promoting a mix of measures including privatisation, monetisation and a wider involvement of the private sector in their management.

  12. Development of the output monitor with single-chip microcomputer in a time-keeping system.

    Science.gov (United States)

    Zhou, Jiguang; Gong, Yuanfang

    An output monitor has been designed with Intel 8031 single-chip microcomputer for a time working station. The functions of the instrument include the comparable measurement of the clocks, the buffer output of time and frequency signals, the monitoring and alarming of working state etc. The principle and application of the instrument are described.

  13. Hardware efficient monitoring of input/output signals

    Science.gov (United States)

    Driscoll, Kevin R. (Inventor); Hall, Brendan (Inventor); Paulitsch, Michael (Inventor)

    2012-01-01

    A communication device comprises first and second circuits to implement a plurality of ports via which the communicative device is operable to communicate over a plurality of communication channels. For each of the plurality of ports, the communication device comprises: command hardware that includes a first transmitter to transmit data over a respective one of the plurality of channels and a first receiver to receive data from the respective one of the plurality of channels; and monitor hardware that includes a second receiver coupled to the first transmitter and a third receiver coupled to the respective one of the plurality of channels. The first circuit comprises the command hardware for a first subset of the plurality of ports. The second circuit comprises the monitor hardware for the first subset of the plurality of ports and the command hardware for a second subset of the plurality of ports.

  14. Lack of agreement and trending ability of the endotracheal cardiac output monitor compared with thermodilution

    DEFF Research Database (Denmark)

    Møller-Sørensen, H; Hansen, K L; Ostergaard, M

    2012-01-01

    cardiac output (CO) during steady state and with induced haemodynamic changes in patients scheduled for elective cardiac surgery. METHODS: Twenty-five patients were enrolled. After induction of anaesthesia, endotracheal intubation using a dedicated ECOM tube, and insertion of the pulmonary artery catheter......BACKGROUND: Minimally invasive monitoring systems of central haemodynamics are gaining increasing popularity. The present study investigated the precision of the endotracheal cardiac output monitor (ECOM) system and its agreement with pulmonary artery catheter thermodilution (PAC TD) for measuring...

  15. [Intraoperative Visual Evoked Potential Monitoring].

    Science.gov (United States)

    Hayashi, Hironobu; Kawaguchi, Masahiko

    2015-05-01

    Visual evoked potential (VEP) is recorded from the back of the head, which is elicited by retinal stimulation transmitted through optic nerve, optic chiasm, optic tract lateral geniculate body, optic radiation and finally cortical visual area. VEP monitoring did not prevail since 1990s because marked intra-individual difference and instability of VEP recording limited the clinical usefulness under inhalation anesthetic management and techniques of VEP monitoring at the time. However, recent advances in techniques including a new light-stimulating device consisting of high-luminosity LEDs and induction of electroretinography to ascertain the arrival of the stimulus at the retina provided better conditions for stable VEP recording under general anesthesia. In addition, the introduction of total intravenous anesthesia using propofol is important for the successful VEP recordings because inhaled anesthetics have suppressive effect on VEP waveform. Intraoperative VEP has been considered to monitor the functional integrity of visual function during neurosurgical procedures, in which the optic pathway is at a risk of injury. Intraoperative VEP monitoring may allow us to detect reversible damage to the visual pathway intraoperatively and enable us to prevent permanent impairment.

  16. Comparison of an advanced minimally invasive cardiac output monitoring with a continuous invasive cardiac output monitoring during lung transplantation.

    Science.gov (United States)

    Tomasi, Roland; Prueckner, Stephan; Czerner, Stephan; Schramm, Renè; Preissler, Gerhard; Zwißler, Bernhard; von Dossow-Hanfstingl, Vera

    2016-08-01

    The aim of this study was to compare a continuous non-calibrated left heart cardiac index (CI) measurement by arterial waveform analysis (FloTrac(®)/Vigileo(®)) with a continuous calibrated right heart CI measurement by pulmonary artery thermodilution (CCOmbo-PAC(®)/Vigilance II(®)) for hemodynamic monitoring during lung transplantation. CI was measured simultaneously by both techniques in 13 consecutive lung transplants (n = 4 single-lung transplants, n = 9 sequential double-lung transplants) at distinct time points perioperatively. Linear regression analysis and Bland-Altman analysis with percentage error calculation were used for statistical comparison of CI measurements by both techniques. In this study the FloTrac(®) system underestimated the CI in comparison with the continuous pulmonary arterial thermodilution (p waveform and continuous pulmonary artery thermodilution are, therefore, not interchangeable during these complex operations.

  17. Intraoperative monitoring of evoked potentials.

    Science.gov (United States)

    Raudzens, P A

    1982-01-01

    Sensory EPs were recorded intraoperatively in 173 neurosurgical procedures (71 VEPs, 66 BAEPs, and 31 SSEPs) to evaluate the utility of this technique. EPs could be safely recorded in all cases, but the yield of useful results varied with each sensory modality. BAEPs were recorded reliably in 100% of the cases and intraoperative latency changes accurately predicted postoperative hearing deficits in 10%. Potential hearing deficits were detected in another 15%. BAEP changes were associated with brainstem dysfunction in only one case. VEP changes were difficult to interpret intraoperatively because of contamination by a high degree of variability and both false negative and false positive results. Changes in VEP amplitudes related to surgical manipulation of the optic chiasm were only suggested. SSEP changes were recorded reliably in only 75% of the cases and no correlations between SSEP changes and postoperative sensory function were established. Again, intraoperative amplitude attenuation of the SSEP waveform with surgical manipulation only suggested a potential sensory deficit. Intraoperative EP monitoring is a valuable technique that provides a functional analysis of the sensory nervous system during surgical procedures. Specific sensory stimuli and improved data analysis will increase the utility of this CNS monitor.

  18. A simple method of monitoring carbon dioxide output in anaesthetized patients.

    Science.gov (United States)

    Christensen, K N

    1977-01-01

    The mean CO2 output during anaesthesia in paralyzed patients can be monitored by continuous capnographic analysis of the total exhaled gases, the latter being mechanically integrated by pumice canisters. The gas is evacuated from the Hafnia A circuit via an ejector flowmeter. The results are not influenced by the flow rates employed.

  19. [Arterial pressure-based cardiac output monitoring: 1. FloTrac sensor and SVV].

    Science.gov (United States)

    Seo, Katsuhiro

    2009-07-01

    FloTrac is a recently introduced semi-invasive arterial pressure-based cardiac output (APCO) monitoring device. The accuracy of a new device is usually evaluated by Bland-Altman method, which shows graphically the mean value of differences between a new method and the reference method (bias), standard deviation of the differences (precision) and limits of agreement or 2 standard deviations. Critchley et al calculated the percentage errors which are two standard deviations divided by mean cardiac output, and proposed that percentage error should be less than 30% as a reliable new method. Cardiac output was measured by FloTrac (APCO) and pulmonary arterial catheter-based thermodilution method (ICO) during off-pump coronary artery bypass and resection of pheochromocytoma, procedures associated with hemodynamically unstable conditions. As algorithm is renewed in a new version of the device, the accuracy of the device is improved; bias, precision and limits of agreement decreased; correlation coefficient increased, and percentage error was assessed to be around 30%. On the other hand, there was a tendency for increased negative bias as cardiac output increased, implying APCO tends to underestimate ICO in high CO ranges. APCO is less invasive and could rapidly respond to fast changes of hemodynamic state. FloTrac is expected to become a reliable cardiac output monitoring device even under hemodynamically unstable conditions. Further improvement of the algorithm is anticipated.

  20. Estimating changes in cardiac output using an implanted hemodynamic monitor in heart failure patients

    DEFF Research Database (Denmark)

    Ståhlberg, Marcus; Damgaard, Morten; Ersgård, David;

    2010-01-01

    OBJECTIVES: The aim of this study was to evaluate an algorithm that estimates changes in cardiac output (CO) from right ventricular (RV) pressure waveforms derived from an implantable hemodynamic monitor (IHM) in heart failure patients. DESIGN: Twelve heart failure patients (NYHA II-III, EF 32......%) with an implantable hemodynamic monitor (Chronicle) were included in this study. Changes in cardiac output were provoked by body position change at rest (left lateral supine, horizontal supine, sitting, and standing) and a steady state bicycle exercise at 20 watts. Estimated CO derived from the IHM (CO...... was -0.39 L/min (11%). Limits of agreement were +/-1.56 L/min and relative error was 21%. CONCLUSIONS: A simple algorithm based on RV pressure wave form characteristics derived from an IHM can be used to estimate changes in CO in heart failure patients. These findings encourage further research aiming...

  1. Intelligent Monitoring and Predicting Output Power Losses of Solar Arrays Based on Particle Filtering

    Directory of Open Access Journals (Sweden)

    Hongzheng Fang

    2013-01-01

    Full Text Available Solar arrays are the main source of energy to the on-orbit satellite, whose output power largely determines the life cycle of on-orbit satellites. Monitoring and further forecasting the output power of solar arrays by using the real-time observational data are very important for the study of satellite design and on-orbit satellite control. In this paper, we firstly describe the dynamical model of output power with summarizing the influencing factors of attenuation for solar arrays and elaborating the evolution trend of influencing factors which change with time. Based on the empirical model, a particle filtering algorithm is formulated to predict the output power of solar arrays and update the model parameters, simultaneously. Finally, using eight-year observational data of voltage and current from a synchronous on-orbit satellite, an experiment is carried out to illustrate the reliability and accuracy of the particle filtering method. Comparative results with classical curve fitting also are presented with statistical root mean square error and mean relative error analysis.

  2. Peripartum cardiomyopathy: postpartum decompensation and use of non-invasive cardiac output monitoring.

    Science.gov (United States)

    Lorello, G; Cubillos, J; McDonald, M; Balki, M

    2014-02-01

    The utility of a non-invasive cardiac output monitor (NICOM™) in guiding the peripartum management and identification of postpartum complications in a patient with severe peripartum cardiomyopathy is reported. A 31-year-old nulliparous woman at 35 weeks of gestation presented with a three-week history of worsening dyspnea and progressive functional deterioration. A transthoracic echocardiogram showed severe left ventricular systolic dysfunction with an ejection fraction peripartum cardiomyopathy. We suggest that use of NICOM™ be extended into the postpartum period to detect signs of cardiac decompensation in such patients.

  3. A New Device to Automate the Monitoring of Critical Patients’ Urine Output

    Directory of Open Access Journals (Sweden)

    Abraham Otero

    2014-01-01

    Full Text Available Urine output (UO is usually measured manually each hour in acutely ill patients. This task consumes a substantial amount of time. Furthermore, in the literature there is evidence that more frequent (minute-by-minute UO measurement could impact clinical decision making and improve patient outcomes. However, it is not feasible to manually take minute-by-minute UO measurements. A device capable of automatically monitoring UO could save precious time of the healthcare staff and improve patient outcomes through a more precise and continuous monitoring of this parameter. This paper presents a device capable of automatically monitoring UO. It provides minute by minute measures and it can generate alarms that warn of deviations from therapeutic goals. It uses a capacitive sensor for the measurement of the UO collected within a rigid container. When the container is full, it automatically empties without requiring any internal or external power supply or any intervention by the nursing staff. In vitro tests have been conducted to verify the proper operation and accuracy in the measures of the device. These tests confirm the viability of the device to automate the monitoring of UO.

  4. A modified Taylor rule for dealing with demand shocks and uncertain potential macroeconomic output

    Science.gov (United States)

    Alvarez-Ramirez, Jose; Ibarra-Valdez, Carlos; Fernandez-Anaya, Guillermo; Villarreal, Francisco

    2008-02-01

    A critical issue for central banks in modern economies is the inflation stabilization about a prescribed level. The best-known simple instrumental rule to guide monetary policy to control inflation is the Taylor rule, where the instrument (e.g., a short interest rate) responds to changes in the inflation and the output gaps. The objective of this paper is to introduce some modifications to the Taylor rule in order to improve its robustness with respect to uncertainties about potential output and unanticipated shocks. To this end, departing from feedback control theory, the Taylor rule is equipped with an adaptive control scheme to reject the adverse effects of shocks and to estimate the deviations of the potential output. It is shown that the proposed adaptation procedure is equivalent to a classical integral feedback controller whose characteristics and implementation issues are well understood in practical control engineering. Singular perturbation methods are used to establish the stability properties of the resulting control system.

  5. Cardiac output measurement in newborn infants using the ultrasonic cardiac output monitor: an assessment of agreement with conventional echocardiography, repeatability and new user experience.

    Science.gov (United States)

    Patel, Neil; Dodsworth, Melissa; Mills, John F

    2011-05-01

    To assess (1) agreement between the ultrasonic cardiac output monitor (USCOM) 1A device for measurement of cardiac output in newborn infants and conventional echocardiography (ECHO), (2) repeatability of USCOM measurements and (3) agreement between novice and expert users of the USCOM. A prospective observational study. The Neonatal Unit at the Royal Children's Hospital, Melbourne, Australia. 56 term and near-term infants, with no evidence of structural or functional cardiovascular disease, or haemodynamic shunts. Agreement between ECHO and USCOM was assessed by paired measurements of ventricular outputs by a single experienced user. Repeatability was assessed using five repeated measurements in 10 infants. Agreement between five novices and one expert user was assessed by paired USCOM measurements over 30 training measurements. Agreement between USCOM and ECHO for left ventricular output (LVO) was (bias, ±limits of agreement, mean % error): 14, ±108 ml/kg/min, 43%, and for right ventricular output (RVO): -59, ±160, ml/kg/min, 57%. Intra-observer repeatability was 6.7% for USCOM LVO and 3.6% for ECHO LVO. After five training measurements, the mean difference between USCOM measures of LVO by novice and expert users was less than 50 ml/kg/min, but with variability. Repeatability of USCOM measures is high in newborn infants. New users can be trained quickly, but with high inter-user variability. Agreement between USCOM and conventional ECHO is broad, and worse for RVO and LVO. Further studies are required to assess the ability of the device to detect clinically significant changes in infant cardiac output.

  6. Monitoring dental-unit-water-line output water by current in-office test kits.

    Science.gov (United States)

    Lal, Sham; Singhrao, Sim K; Bricknell, Matt; Pearce, Mark; Morton, L H Glyn; Ahmed, Waqar; Crean, St John

    2014-08-01

    The importance of monitoring contamination levels in the output water of dental-unit-water-lines (DUWLs) is essential as they are prone to developing biofilms that may contaminate water that is used to treat patients, with opportunistic pathogens such as species of Legionella, Pseudomonas and others. Dentists and practice staff are also at risk of being infected by means of cross-infection due to aerosols generated from DUWL water. The unit of measurement for the microbial contamination of water by aerobic mesophilic heterotrophic bacteria is the colony-forming unit per millilitre (cfu/ml) of water. The UK has its own guidelines set by the Department of Health for water discharged from DUWL to be between 100 and 200 cfu/ml of water. The benchmark or accepted standard laboratory test is by microbiological culture on R2A agar plates. However, this is costly and not convenient for routine testing in dental practices. A number of commercial indicator tests are used in dental surgeries, but they were not developed for the dental market and serve only to indicate gross levels of contamination when used outside of the manufacturer's recommended incubation period. The aim of this article is to briefly review the universal problem of DUWL contamination with microbial biofilms and to update dental professionals on the availability of currently available commercial in-office monitoring systems for aerobic mesophilic heterotrophic bacteria and to discuss their limitations for testing water samples in assuring compliance with recommended guidelines.

  7. Enteral nutrition. Potential complications and patient monitoring.

    Science.gov (United States)

    Kohn, C L; Keithley, J K

    1989-06-01

    Enteral feedings are safely tolerated by most patients. When complications occur, gastrointestinal disturbances are most frequently encountered, followed by mechanical and metabolic complications. Nurses can prevent many of the problems associated with enteral feeding through careful monitoring. Based on the current literature, the authors make the following recommendations: 1. All patients receiving tube feedings should be placed on a protocol that provides guidelines for (a) confirming correct tube placement; (b) preventing/managing tube obstruction; (c) handling and selecting formulas; (d) administering formulas; and (e) monitoring patients. 2. Fine-bore tubes are easily misplaced or dislodged; ensure correct positioning both before and during feeding. Food coloring should be added to all feedings to help detect aspiration/tube displacement. 3. Multiple factors can cause diarrhea in tube-fed patients and, therefore, require periodic assessment. These factors include concomitant drug therapy; malnutrition/hypoalbuminemia; formula-related factors (for example, lactose content, osmolality); and bacterial contamination. 4. Urine sugar and acetone levels should be checked every 6 hours (until stable). Vital signs and fluid intake and output should be determined every 8 hours, and weight should be measured on a daily basis. Serum electrolytes, blood urea nitrogen, and glucose levels should be determined daily, until serum levels stabilize. Weekly measurements of trace elements should be made to ensure adequate mineral replacement. 5. Use a controller pump to administer continuous feedings at a constant rate or to administer formulas that are viscous. Flush feeding tubes with water every 4 hours during continuous feedings, after giving intermittent feedings, after giving medications, and after checking for gastric residuals. If tube obstruction occurs, attempt to irrigate the tube with either water or cola. 6. Select feedings that contain appropriate nutrient sources

  8. An investigation of the orthogonal outputs from an on-rotor MEMS accelerometer for reciprocating compressor condition monitoring

    Science.gov (United States)

    Feng, G.; Hu, N.; Mones, Z.; Gu, F.; Ball, A. D.

    2016-08-01

    With rapid development in electronics and microelectromechanical systems (MEMS) technology, it becomes possible and attractive to monitor rotor dynamics by directly installing MEMS accelerometers on rotors. This paper studies the mathematical modelling of the orthogonal outputs from an on-rotor MEMS accelerometer and proposes a method to eliminate the gravitational acceleration projected on the measurement axes. This is achieved by shifting the output in the normal direction by π / 2 using a Hilbert transform and then combining it with the output of the tangential direction. With further compensation of the combined signal in the frequency domain, the tangential acceleration of the rotor is reconstructed to a high degree of accuracy. Experimental results show that the crankshaft tangential acceleration of a reciprocating compressor, obtained by the proposed method, can discriminate clearly between different discharge pressures and hence can allow common leakage faults to be detected, located and diagnosed for online condition monitoring purposes.

  9. [Anesthesia management of geriatric patients with arterial pressure-based cardiac output monitoring FloTrac sensor for emergency surgery].

    Science.gov (United States)

    Yamamoto, Shunsuke; Goto, Koji; Yasuda, Norihisa; Kusaka, Junya; Hidaka, Seigo; Miyakawa, Hiroshi; Noguchi, Takayuki

    2009-06-01

    In cases of emergency surgery for geriatric patients, immediate anesthesia induction and careful intraoperative management is necessary without sufficient preoperative information. We report anesthesia management of a 96-year and a 90-year old patients with FloTrac sensor which is an arterial pressure-based cardiac output monitoring device and is able to manage critical patients effectively and safely during anesthesia.

  10. Hybrid measurement to achieve satisfactory precision in perioperative cardiac output monitoring.

    Science.gov (United States)

    Peyton, P

    2014-05-01

    Advanced haemodynamic monitoring employing minimally invasive cardiac output measurement may lead to significant improvements in patient outcomes in major surgery. However, the precision (scatter) of measurement of available generic technologies has been shown to be unsatisfactory with percentage error of agreement with bolus thermodilution (% error) of 40% to 50%. Simultaneous measurement and averaging by two or more technologies may reduce random measurement scatter and improve precision. This concept, called the hybrid method, was tested by comparing accuracy and precision of measurement relative to bolus thermodilution using combinations of three component methods. Thirty patients scheduled for either elective cardiac surgery or liver transplantation were studied. Agreement with simultaneous bolus thermodilution of hybrid combinations of continuous thermodilution (QtCCO) or Vigeleo™/FloTrac™ pulse contour measurement (QtFT) with pulmonary Capnotracking (QtCO2) was assessed pre- and post-cardiopulmonary bypass or pre- and post-reperfusion of the donor liver and compared with that of the component methods alone. Hybridisation of QtCO2 (% error 42.2) and QtCCO (% error 51.3) achieved significantly better precision (% error 31.3) than the component methods (P=0.0004) and (P=0.0195). Due to poor inherent precision of QtFT (% error 82.8), hybrid combination of QtFT with QtCO2 did not result in better precision than QtCO2 alone. Hybrid measurement can approach a 30% error, which is recommended as the upper limit for acceptability. This is a practical option where at least one component method, such as Capnotracking, is automated and does not increase the cost or complexity of the measurement process.

  11. [Intraoperative monitoring of visual evoked potentials].

    Science.gov (United States)

    Sasaki, Tatsuya; Ichikawa, Tsuyoshi; Sakuma, Jun; Suzuki, Kyouichi; Matsumoto, Masato; Itakura, Takeshi; Kodama, Namio; Murakawa, Masahiro

    2006-03-01

    Our success rate of intraoperative monitoring of visual evoked potential (VEP) had been approximately 30% in the past. In order to improve recording rate of intraoperative VEP, we developed a new stimulating device using high power light emitting diodes. Electroretinogram was simultaneously recorded to understand whether flash stimulation reached the retina. In addition, total venous anesthesia with propofol was used to avoid the adverse effect of inhalation anesthesia. We report the results after introduction of these improvements. Intraoperative monitoring of VEP was attempted in 35 cases. We evaluated success rate of VEP recording, correlation between VEP findings and postoperative visual function, and reasons why recording was not successful. Stable and reproducible waveforms were obtained in 59 sides (84%). Two cases, whose VEP deteriorated intraoperatively, developed postoperative visual disturbance: In 11 sides (16%), stable waveforms were not obtained. There were two main causes. In 8 sides out of 11, the cause was attributed to pre-existing severe visual disturbance. In these 8 sides, VEP in the awake state was not recordable or was recordable, but with very low amplitudes under 1 microV. In the other 3 sides, the cause was attributed to movement of a stimulating device by reflecting the fronto-temporal scalp flap. In conclusion, the successful recording rate was increased to 84% from approximately 30%, after introduction of various trials. We need further improvement in recording intraoperative VEP to establish a reliable intraoperative monitoring method for VEP.

  12. T-type calcium channels consolidate tonic action potential output of thalamic neurons to neocortex.

    Science.gov (United States)

    Deleuze, Charlotte; David, François; Béhuret, Sébastien; Sadoc, Gérard; Shin, Hee-Sup; Uebele, Victor N; Renger, John J; Lambert, Régis C; Leresche, Nathalie; Bal, Thierry

    2012-08-29

    The thalamic output during different behavioral states is strictly controlled by the firing modes of thalamocortical neurons. During sleep, their hyperpolarized membrane potential allows activation of the T-type calcium channels, promoting rhythmic high-frequency burst firing that reduces sensory information transfer. In contrast, in the waking state thalamic neurons mostly exhibit action potentials at low frequency (i.e., tonic firing), enabling the reliable transfer of incoming sensory inputs to cortex. Because of their nearly complete inactivation at the depolarized potentials that are experienced during the wake state, T-channels are not believed to modulate tonic action potential discharges. Here, we demonstrate using mice brain slices that activation of T-channels in thalamocortical neurons maintained in the depolarized/wake-like state is critical for the reliable expression of tonic firing, securing their excitability over changes in membrane potential that occur in the depolarized state. Our results establish a novel mechanism for the integration of sensory information by thalamocortical neurons and point to an unexpected role for T-channels in the early stage of information processing.

  13. A useful method to monitor outputs from a pulsed light source and its application to rate effect studies in a photomultiplier tube

    CERN Document Server

    Takeuchi, Y; Kurashige, H; Matono, Y; Murakami, K; Nomura, T; Sakamoto, H; Sasao, N; Suehiro, M; Fukushima, Y; Ikegami, Y; Nakamura, T T; Taniguchi, T; Asai, M

    1999-01-01

    In order to study short-term gain stability in a photomultiplier tube at high counting rate, we constructed an LED pulsed light source and its output monitoring system. For the monitoring system, we employed a photon counting method using a photomultiplier as a monitor photon detector. It is found that the method offers a simple way to monitor outputs from a pulsed light source and that, together with an LED light source, it provides a useful method to investigate photomultiplier's rate effects.

  14. Continuous monitoring of plant water potential.

    Science.gov (United States)

    Schaefer, N L; Trickett, E S; Ceresa, A; Barrs, H D

    1986-05-01

    Plant water potential was monitored continuously with a Wescor HR-33T dewpoint hygrometer in conjunction with a L51 chamber. This commercial instrument was modified by replacing the AC-DC mains power converter with one stabilized by zener diode controlled transistors. The thermocouple sensor and electrical lead needed to be thermally insulated to prevent spurious signals. For rapid response and faithful tracking a low resistance for water vapor movement between leaf and sensor had to be provided. This could be effected by removing the epidermis either by peeling or abrasion with fine carborundum cloth. A variety of rapid plant water potential responses to external stimuli could be followed in a range of crop plants (sunflower (Helianthus annuus L., var. Hysun 30); safflower (Carthamus tinctorious L., var. Gila); soybean (Glycine max L., var. Clark); wheat (Triticum aestivum L., var. Egret). These included light dark changes, leaf excision, applied pressure to or anaerobiosis of the root system. Water uptake by the plant (safflower, soybean) mirrored that for water potential changes including times when plant water status (soybean) was undergoing cyclical changes.

  15. Monitoring cardiac output during hyperbaric oxygen treatment of haemodynamically unstable patients

    DEFF Research Database (Denmark)

    Hansen, Marco Bo; Treschow, Frederik; Skielboe, Martin

    2013-01-01

    Patients suffering from necrotizing fasciitis (NF) are often haemodynamically unstable and require extended monitoring of cardiovascular parameters; yet this is limited during hyperbaric oxygen treatment (HBOT). We aimed to evaluate the use and safety of transoesophageal Doppler (TED) monitoring...

  16. Dendritic Na(+) spikes enable cortical input to drive action potential output from hippocampal CA2 pyramidal neurons.

    Science.gov (United States)

    Sun, Qian; Srinivas, Kalyan V; Sotayo, Alaba; Siegelbaum, Steven A

    2014-01-01

    Synaptic inputs from different brain areas are often targeted to distinct regions of neuronal dendritic arbors. Inputs to proximal dendrites usually produce large somatic EPSPs that efficiently trigger action potential (AP) output, whereas inputs to distal dendrites are greatly attenuated and may largely modulate AP output. In contrast to most other cortical and hippocampal neurons, hippocampal CA2 pyramidal neurons show unusually strong excitation by their distal dendritic inputs from entorhinal cortex (EC). In this study, we demonstrate that the ability of these EC inputs to drive CA2 AP output requires the firing of local dendritic Na(+) spikes. Furthermore, we find that CA2 dendritic geometry contributes to the efficient coupling of dendritic Na(+) spikes to AP output. These results provide a striking example of how dendritic spikes enable direct cortical inputs to overcome unfavorable distal synaptic locale to trigger axonal AP output and thereby enable efficient cortico-hippocampal information flow.

  17. A Communication Protocol and Monitoring Policy for Input/Output Vehicles in an Automatic Storage and Retrieval System

    Institute of Scientific and Technical Information of China (English)

    LI Li; LI Wenfeng; LIAO Xiaoping; SU Wengui; LIN Yizhong

    2006-01-01

    The acquisition and processing of equipment information is pivotal to control and management of the automated storage and retrieval system. The work of this paper is based on the automatic storage and retrieval experimental system of Wuhan University of Technology. First, the output/input flow and the control information of storage/retrieval vehicle are studied and the plotting finite state machine model of the stacking crane is established. Then, the communication protocol between the center control management computer and the PLC of stacking crane is designed. Finally, the stacking crane's monitoring data, which include operating time, running states and real-time position status, are gained by analyzing the communication protocol. The detailed program for the acquisition and processing of monitoring information is developed. This method is suitable for the equipment monitoring of the whole system, and provides a platform for studying the intelligent control and optimal scheduling strategies of AS/RS.

  18. Method and apparatus for monitoring motor operated valve motor output torque and power at valve seating

    Science.gov (United States)

    Casada, Donald A.

    1996-01-01

    A method and apparatus are provided for monitoring a motor operated valve during the brief period when the valve seats and the torque switch trips to deenergize the valve motor. The method uses voltage measurements on the load side of a deenergizing switch that opens to deenergize the motor to determine, among other things, final motor rotational speed and the decelerating torque at motor deenergization.

  19. Application of intraoperative arterial pressure-based cardiac output monitoring for patients undergoing coronary artery bypass grafting surgery

    Institute of Scientific and Technical Information of China (English)

    LU Jia-kai; ZHU Chen; JING He; WANG Yi-jun; QING En-ming

    2012-01-01

    Background For patients undergoing off-pump coronary artery bypass grafting (OPCABG),it is important to establish a hemodynamic monitoring system to obtain powerful parameters for better intraoperative treatment.This study aimed to observe the clinical feasibility of artedal pressure-based cardiac output (APCO) for cardiac output (CO) monitoring and to evaluate the correlation between APCO and pulmonary artery catheter (PAC) for CO measurement for patients undergoing OPCABG intraoperatively.Methods Fifty patients of Amedcan Society of Anaesthesiologists (ASA) classification Ⅱ-Ⅲ,undergoing elective OPCABG at Beijing Anzhen Hospital were randomly enrolled into this study.All patients were assigned to CO monitoring by PAC and APCO simultaneously.Patients with pacemaker,severe valvular heart disease,left ventdcular ejection fraction (EF) <40%,cardiac arrhythmias,peripheral vascular disease,application of intra-aortic balloon pump (IABP) and emergent diversion to cardiac pulmonary bypass were excluded.The radial artery wavaform was analyzed to estimate the stroke volume (SV) and heart rate (HR) continuously.CO was calculated as SV x HR; other derived parameters were cardiac index (CI),stroke volume index (SVI),systemic vascular resistance (SVR),and systemic vascular resistance index (SVRI).PAC was placed via right internal jugular vein and the correct position was confirmed by PAC waveforms.Continuous cardiac output (CCO),CI and other hemodynamic parameters were monitored at following 5 time points:immediate after anesthesia induction (baseline value),anastomosis of left intemal mammary artery to left anterior descending artery (LAD),anastomosis of left circumflex (LCX),anastomosis of posterior descending artery (PDA) and immediate after sternal closure.Results In the 50 patients,preoperative echocardiography measured left ventricular EF was (52.8±11.5)%,and 35 patients (70%) showed regional wall motion abnormalities.The correlation coefficient of CO

  20. Comparison of output-only methods for condition monitoring of industrials systems

    Energy Technology Data Exchange (ETDEWEB)

    Rutten, C; Nguyen, V-H; Golinval, J-C, E-mail: Christophe.Rutten@ulg.ac.be, E-mail: VH.nguven@doct.ulg.ac.be, E-mail: JC.Golinval@ulg.ac.be [University of Liege, Department of Mechanical Engineering, LTAS-Vibrations and Identification of Structures Chemin des Chevreuils 1, 4000 Liege (Belgium)

    2011-07-19

    In the field of structural health monitoring or machine condition monitoring, the activation of nonlinear dynamic behavior complicates the procedure of damage or fault detection. Blind source separation (BSS) techniques are known as efficient methods for damage diagnosis. However, most of BSS techniques repose on the assumption of the linearity of the system and the need of many sensors. This article presents some possible extensions of those techniques that may improve the damage detection, e.g. Enhanced-Principal Component Analysis (EPCA), Kernel PCA (KPCA) and Blind Modal Identification (BMID). The advantages of EPCA rely on its rapidity of use and its reliability. The KPCA method, through the use of nonlinear kernel functions, allows to introduce nonlinear dependences between variables. BMID is adequate to identify and to detect damage for generally damped systems. In this paper, damage is firstly examined by Stochastic Subspace Identification (SSI); then the detection is achieved by comparing subspace features between the reference and a current state through statistics and the concept of subspace angle. Industrial data are used as illustration of the methods.

  1. Determination Of X-Ray Tube Potential (kV) Waveform By A Noninvasive Evaluation Of Radiation Output (NERO)

    Science.gov (United States)

    Simon, William E.; Richards, Doug

    1981-07-01

    A method has been developed to noninvasively measure the instantaneous potential (kV) applied to an x-ray tube. The method uses differentially filtered x-ray detectors whose outputs during the exposure are converted to digital signals and stored in a memory array. The conversions are made every 125 microseconds. After the exposure, a microprocessor calculates the ratios of the detector outputs; computes the kV waveform from stored calibration data; and digitally displays the kV value. A resolution of +/-0.5 kV at 110 kV has been achieved.

  2. Characteristic monitoring of groundwater-salt transportation and input-output in inland arid irrigation area.

    Science.gov (United States)

    Xu, Cundong; Zhang, Hongyang; Han, Liwei; Zhai, Luxin

    2014-11-01

    The rules of microscopic water-salt transportation can be revealed and the impact on the macroscopic water and soil resources can be further predicted by selecting a typical study area and carrying out continuous monitoring. In this paper, Jingtaichuan Electrical Lifting Irrigation District in Gansu Province (hereinafter called as JingDian irrigation district (JID)) located at the inland desert region of northwest China was selected as study area. Based on the groundwater-salt transportation data of representative groundwater monitoring wells in different hydrogeological units, the groundwater-salt evolution and transportation tendency in both closed and unclosed hydrogeological units were analyzed and the quantity relative ratio relationship of regional water-salt input-excretion was calculated. The results showed that the salt brought in by artificial irrigation accounts for the highest proportion of about 63.99% and the salt carried off by the discharge of irrigation water accounts for 66.42%, namely, the water-salt evolution and transportation were mainly controlled by artificial irrigation. As the general features of regional water-salt transportation, groundwater salinity and soil salt content variation were mainly decided by the transportation of soil soluble salt which showed an obvious symbiosis gathering regularity, but the differentiation with insoluble salt components was significant in the transportation process. Besides, groundwater salinity of the unclosed hydrogeological unit presented a periodically fluctuating trend, while the groundwater salinity and soil salt content in water and salt accumulation zone of the closed hydrogeological unit showed an increasing tendency, which formed the main occurrence area of soil secondary salinization.

  3. Analysis of the innovation outputs in mHealth for patient monitoring

    NARCIS (Netherlands)

    Villalonga, Claudia; Pomares, Hector; Banos Legran, Oresti

    2016-01-01

    Abstract—In the last decade, mobile health (mHealth) has developed as a natural consequence of the advances in mobile technologies, the growing spread of mobile devices, and their application in the provision of novel health services. mHealth has demonstrated the potential to make the health care

  4. Fungal infection intensity and zoospore output of Atelopus zeteki, a potential acute chytrid supershedder.

    Directory of Open Access Journals (Sweden)

    Graziella V Direnzo

    Full Text Available Amphibians vary in their response to infection by the amphibian-killing chytrid fungus, Batrachochytrium dendrobatidis (Bd. Highly susceptible species are the first to decline and/or disappear once Bd arrives at a site. These competent hosts likely facilitate Bd proliferation because of ineffective innate and/or acquired immune defenses. We show that Atelopus zeteki, a highly susceptible species that has undergone substantial population declines throughout its range, rapidly and exponentially increases skin Bd infection intensity, achieving intensities that are several orders of magnitude greater than most other species reported. We experimentally infected individuals that were never exposed to Bd (n = 5 or previously exposed to an attenuated Bd strain (JEL427-P39; n = 3. Within seven days post-inoculation, the average Bd infection intensity was 18,213 zoospores (SE: 9,010; range: 0 to 66,928. Both average Bd infection intensity and zoospore output (i.e., the number of zoospores released per minute by an infected individual increased exponentially until time of death (t50 = 7.018, p<0.001, t46 = 3.164, p = 0.001, respectively. Mean Bd infection intensity and zoospore output at death were 4,334,422 zoospores (SE: 1,236,431 and 23.55 zoospores per minute (SE: 22.78, respectively, with as many as 9,584,158 zoospores on a single individual. The daily percent increases in Bd infection intensity and zoospore output were 35.4% (SE: 0.05 and 13.1% (SE: 0.04, respectively. We also found that Bd infection intensity and zoospore output were positively correlated (t43 = 3.926, p<0.001. All animals died between 22 and 33 days post-inoculation (mean: 28.88; SE: 1.58. Prior Bd infection had no effect on survival, Bd infection intensity, or zoospore output. We conclude that A. zeteki, a highly susceptible amphibian species, may be an acute supershedder. Our results can inform epidemiological models to estimate Bd outbreak probability, especially as they relate

  5. Climate Change Impacts on Oklahoma Wind Resources: Potential Energy Output Changes

    Directory of Open Access Journals (Sweden)

    Stephen Stadler

    2015-04-01

    Full Text Available An extensive literature on climate change modeling points to future changes in wind climates. Some areas are projected to gain wind resources, while others are projected to lose wind resources. Oklahoma is presently wind rich with this resource extensively exploited for power generation. Our work examined the wind power implications under the IPCC’s A2 scenario for the decades 2040–2049, 2050–2059 and 2060–2069 as compared to model reanalysis and Oklahoma Mesonetwork observations for the base decade of 1990–1999. Using two western Oklahoma wind farms as examples, we used North American Regional Climate Change Assessment Program (NARCCAP modeling outputs to calculate changes in wind power generation. The results show both wind farms to gain in output for all decades as compared to 1990–1999. Yet, the results are uneven by seasons and with some decades exhibiting decreases in the fall. These results are of interest in that it is clear that investors cannot count on wind studies of the present to adequately characterize future productivity. If our results are validated over time, Oklahoma stands to gain wind resources through the next several decades.

  6. Potential role of motion for enhancing maximum output energy of triboelectric nanogenerator

    Science.gov (United States)

    Byun, Kyung-Eun; Lee, Min-Hyun; Cho, Yeonchoo; Nam, Seung-Geol; Shin, Hyeon-Jin; Park, Seongjun

    2017-07-01

    Although triboelectric nanogenerator (TENG) has been explored as one of the possible candidates for the auxiliary power source of portable and wearable devices, the output energy of a TENG is still insufficient to charge the devices with daily motion. Moreover, the fundamental aspects of the maximum possible energy of a TENG related with human motion are not understood systematically. Here, we confirmed the possibility of charging commercialized portable and wearable devices such as smart phones and smart watches by utilizing the mechanical energy generated by human motion. We confirmed by theoretical extraction that the maximum possible energy is related with specific form factors of a TENG. Furthermore, we experimentally demonstrated the effect of human motion in an aspect of the kinetic energy and impulse using varying velocity and elasticity, and clarified how to improve the maximum possible energy of a TENG. This study gives insight into design of a TENG to obtain a large amount of energy in a limited space.

  7. Monitoring system of technological innovation potential on the market

    Directory of Open Access Journals (Sweden)

    O.P. Kosenko

    2016-12-01

    Full Text Available The aim of the article. The main purpose of the study is to develop practical tools for monitoring and evaluating commercial potential results of creative industry and identify strategic directions for their further developments. The results of the analysis. The article confirmed that timely monitoring of the enterprise intellectual potential and commercial possibilities of the individual technological developments can become the basis for points of growth identification, early detecting of negative trends, determining the optimal ratio of both traditional and new areas of the enterprise. The results of the monitoring process are also needed for managing decisions at both the enterprise and at the regional level of the country. So in this case we can consider very relevant the development of algorithms for monitoring and evaluating commercial potential of intellectual development industry. It is proved that the accuracy and objectivity of the current state of the technological innovation commercial potential depends more on the potential economic benefit that is available for developers of technological innovations in their commercialization, and consumer technology in their use. With economic effect parameters developer and consumer of technological innovation generated tangential monitoring function and economic characteristics defined set of values. It is proposed to improve the accuracy and reliability of the results to take into account quality monitoring of technological developments and commercial risk implementation. Proposed to take into account the indicators during the monitoring process Placed sponsored task performed using arctangent monitoring function that includes the integral index of a technology and successful commercialization state of the risk ,also was calculated the number of factors affecting it. It was proved that the most efficient monitoring of commercial potential (level of market attractiveness with technological

  8. Potential role of motion for enhancing maximum output energy of triboelectric nanogenerator

    Directory of Open Access Journals (Sweden)

    Kyung-Eun Byun

    2017-07-01

    Full Text Available Although triboelectric nanogenerator (TENG has been explored as one of the possible candidates for the auxiliary power source of portable and wearable devices, the output energy of a TENG is still insufficient to charge the devices with daily motion. Moreover, the fundamental aspects of the maximum possible energy of a TENG related with human motion are not understood systematically. Here, we confirmed the possibility of charging commercialized portable and wearable devices such as smart phones and smart watches by utilizing the mechanical energy generated by human motion. We confirmed by theoretical extraction that the maximum possible energy is related with specific form factors of a TENG. Furthermore, we experimentally demonstrated the effect of human motion in an aspect of the kinetic energy and impulse using varying velocity and elasticity, and clarified how to improve the maximum possible energy of a TENG. This study gives insight into design of a TENG to obtain a large amount of energy in a limited space.

  9. Accuracy and precision of minimally-invasive cardiac output monitoring in children: a systematic review and meta-analysis.

    Science.gov (United States)

    Suehiro, Koichi; Joosten, Alexandre; Murphy, Linda Suk-Ling; Desebbe, Olivier; Alexander, Brenton; Kim, Sang-Hyun; Cannesson, Maxime

    2016-10-01

    Several minimally-invasive technologies are available for cardiac output (CO) measurement in children, but the accuracy and precision of these devices have not yet been evaluated in a systematic review and meta-analysis. We conducted a comprehensive search of the medical literature in PubMed, Cochrane Library of Clinical Trials, Scopus, and Web of Science from its inception to June 2014 assessing the accuracy and precision of all minimally-invasive CO monitoring systems used in children when compared with CO monitoring reference methods. Pooled mean bias, standard deviation, and mean percentage error of included studies were calculated using a random-effects model. The inter-study heterogeneity was also assessed using an I(2) statistic. A total of 20 studies (624 patients) were included. The overall random-effects pooled bias, and mean percentage error were 0.13 ± 0.44 l min(-1) and 29.1 %, respectively. Significant inter-study heterogeneity was detected (P error (23.6 %). Significant residual heterogeneity remained after conducting sensitivity and subgroup analyses based on the various study characteristics. By meta-regression analysis, we found no independent effects of study characteristics on weighted mean difference between reference and tested methods. Although the pooled bias was small, the mean pooled percentage error was in the gray zone of clinical applicability. In the sub-group analysis, electrical cardiometry was the device that provided the most accurate measurement. However, a high heterogeneity between studies was found, likely due to a wide range of study characteristics.

  10. Intraoperative Monitoring: Recent Advances in Motor Evoked Potentials.

    Science.gov (United States)

    Koht, Antoun; Sloan, Tod B

    2016-09-01

    Advances in electrophysiological monitoring have improved the ability of surgeons to make decisions and minimize the risks of complications during surgery and interventional procedures when the central nervous system (CNS) is at risk. Individual techniques have become important for identifying or mapping the location and pathway of critical neural structures. These techniques are also used to monitor the progress of procedures to augment surgical and physiologic management so as to reduce the risk of CNS injury. Advances in motor evoked potentials have facilitated mapping and monitoring of the motor tracts in newer, more complex procedures.

  11. Understanding the overall shape of the output characteristics from the change in the channel potential profile for nanowire FET

    Science.gov (United States)

    Sarkar, Niladri

    2017-01-01

    We have shown the influence of the changing channel potential profile from its equilibrium profile on the overall shape of the output characteristics of a Nanowire FET which is operating under ballistic regime. The device has a nano-wire channel with an array of lattice points which is the surrounded by a coaxial metallic gate. There is a dielectric which isolates the channel from the metallic gate. The source and the drain electrodes are maintained at different chemical potentials μ1 and μ2 which gives rise to the channel current in the device. The physics and the modeling of this device have been understood in detail by studying the electrostatics of the channel.

  12. Remote monitoring of biodynamic activity using electric potential sensors

    Energy Technology Data Exchange (ETDEWEB)

    Harl, C J; Prance, R J; Prance, H [Centre for Physical Electronics and Quantum Technology, Department of Engineering and Design, School of Science and Technology, University of Sussex, Brighton, BN1 9QT (United Kingdom)], E-mail: c.j.harland@sussex.ac.uk

    2008-12-01

    Previous work in applying the electric potential sensor to the monitoring of body electrophysiological signals has shown that it is now possible to monitor these signals without needing to make any electrical contact with the body. Conventional electrophysiology makes use of electrodes which are placed in direct electrical contact with the skin. The electric potential sensor requires no cutaneous electrical contact, it operates by sensing the displacement current using a capacitive coupling. When high resolution body electrophysiology is required a strong (capacitive) coupling is used to maximise the collected signal. However, in remote applications where there is typically an air-gap between the body and the sensor only a weak coupling can be achieved. In this paper we demonstrate that the electric potential sensor can be successfully used for the remote sensing and monitoring of bioelectric activity. We show examples of heart-rate measurements taken from a seated subject using sensors mounted in the chair. We also show that it is possible to monitor body movements on the opposite side of a wall to the sensor. These sensing techniques have biomedical applications for non-contact monitoring of electrophysiological conditions and can be applied to passive through-the-wall surveillance systems for security applications.

  13. Monitoring the electrochemical potential noise produced by coated metal electrodes

    Energy Technology Data Exchange (ETDEWEB)

    Metikos-Hukovic, M. (Zagreb Univ. (Yugoslavia). Inst. of Electrochemistry); Loncar, M. (Institute of Metallurgy, Sisak (Yugoslavia)); Zevnik, C. (Iskra-Kibernetika, Kranj (Yugoslavia))

    1989-08-01

    The protective properties of paints with polyvinyl phenol formaldehyde and cumar resin bases were tested on mild steel using electrochemical noise measurements. Amplitude spectra of low frequency electrochemical potential noise demonstrated a correlation between the rate and form of the corrosion potential. Such results suggest a practical nondestructive electrochemical corrosion monitoring technique for detecting general corrosion and pitting. The corrosion products were subjected to X-ray diffraction analysis and electron-probe microanalysis. (orig.).

  14. A minimally invasive monitoring system of cardiac output using aortic flow velocity and peripheral arterial pressure profile.

    Science.gov (United States)

    Uemura, Kazunori; Kawada, Toru; Inagaki, Masashi; Sugimachi, Masaru

    2013-05-01

    In managing patients with unstable hemodynamics, monitoring cardiac output (CO) can provide critical diagnostic data. However, conventional CO measurements are invasive, intermittent, and/or inaccurate. The purpose of this study was to validate our newly developed CO monitoring system. This system automatically determines peak velocity of the ascending aortic flow using continuous-wave Doppler transthoracic echocardiography and estimates cardiac ejection time and aortic cross-sectional area using the pulse contour of the radial arterial pressure. These parameters are continuously processed to estimate CO (CO(est)). In 10 anesthetized closed-chest dogs instrumented with an aortic flowprobe to measure reference CO (CO(ref)), hemodynamic conditions were varied over wide ranges by infusing cardiovascular drugs or by random atrial pacing. Under each condition, CO(ref) and CO(est) were determined. Absolute changes of CO(ref) (ΔCOref) and CO(est) (ΔCO(est)), and relative changes of CO(ref) (%ΔCO(ref)) and CO(est) (%ΔCO(est)) from the corresponding baseline values were determined in each animal. We calibrated CO(est) against CO(ref) to obtain proportionally scaled CO(est) (CO(est)(N)). A total of 1335 datasets of CO(ref) and CO(est) were obtained, in which CO(ref) ranged from 0.17 to 5.34 L/min. Bland-Altman analysis between CO(ref) and CO(est) indicated that the limits of agreement (the bias ± 1.96 × SD of the difference) and the percentage error (1.96 × [SD of the difference]/[mean CO] × 100) were from -1.01 to 1.13 L/min (95% confidence interval, -1.76 to 1.88 L/min) and 43%, respectively. The agreement between CO(ref) and CO(est)(N) was improved, with limits of agreement from -0.53 to 0.49 L/min (95% confidence interval, -0.62 to 0.59 L/min) and the percentage error of 20%. Polar plot analysis between ΔCO(ref) and ΔCO(est) indicated that mean ± 1.96 × SD of polar angle was -2° ± 22°. Four quadrant plot analysis indicated that %ΔCO(est) correlated

  15. Bipolar stacked quasi-all-solid-state lithium secondary batteries with output cell potentials of over 6 V

    Science.gov (United States)

    Matsuo, Takahiro; Gambe, Yoshiyuki; Sun, Yan; Honma, Itaru

    2014-01-01

    Designing a lithium ion battery (LIB) with a three-dimensional device structure is crucial for increasing the practical energy storage density by avoiding unnecessary supporting parts of the cell modules. Here, we describe the superior secondary battery performance of the bulk all-solid-state LIB cell and a multilayered stacked bipolar cell with doubled cell potential of 6.5 V, for the first time. The bipolar-type solid LIB cell runs its charge/discharge cycle over 200 times in a range of 0.1–1.0 C with negligible capacity decrease despite their doubled output cell potentials. This extremely high performance of the bipolar cell is a result of the superior battery performance of the single cell; the bulk all-solid-state cell has a charge/discharge cycle capability of over 1500 although metallic lithium and LiFePO4 are employed as anodes and cathodes, respectively. The use of a quasi-solid electrolyte consisting of ionic liquid and Al2O3 nanoparticles is considered to be responsible for the high ionic conductivity and electrochemical stability at the interface between the electrodes and the electrolyte. This paper presents the effective applications of SiO2, Al2O3, and CeO2 nanoparticles and various Li+ conducting ionic liquids for the quasi-solid electrolytes and reports the best ever known cycle performances. Moreover, the results of this study show that the bipolar stacked three-dimensional device structure would be a smart choice for future LIBs with higher cell energy density and output potential. In addition, our report presents the advantages of adopting a three-dimensional cell design based on the solid-state electrolytes, which is of particular interest in energy-device engineering for mobile applications. PMID:25124398

  16. Differential-output B-dot and D-dot monitors for current and voltage measurements on a 20-MA, 3-MV pulsed-power accelerator

    Directory of Open Access Journals (Sweden)

    T. C. Wagoner

    2008-10-01

    Full Text Available We have developed a system of differential-output monitors that diagnose current and voltage in the vacuum section of a 20-MA 3-MV pulsed-power accelerator. The system includes 62 gauges: 3 current and 6 voltage monitors that are fielded on each of the accelerator’s 4 vacuum-insulator stacks, 6 current monitors on each of the accelerator’s 4 outer magnetically insulated transmission lines (MITLs, and 2 current monitors on the accelerator’s inner MITL. The inner-MITL monitors are located 6 cm from the axis of the load. Each of the stack and outer-MITL current monitors comprises two separate B-dot sensors, each of which consists of four 3-mm-diameter wire loops wound in series. The two sensors are separately located within adjacent cavities machined out of a single piece of copper. The high electrical conductivity of copper minimizes penetration of magnetic flux into the cavity walls, which minimizes changes in the sensitivity of the sensors on the 100-ns time scale of the accelerator’s power pulse. A model of flux penetration has been developed and is used to correct (to first order the B-dot signals for the penetration that does occur. The two sensors are designed to produce signals with opposite polarities; hence, each current monitor may be regarded as a single detector with differential outputs. Common-mode-noise rejection is achieved by combining these signals in a 50-Ω balun. The signal cables that connect the B-dot monitors to the balun are chosen to provide reasonable bandwidth and acceptable levels of Compton drive in the bremsstrahlung field of the accelerator. A single 50-Ω cable transmits the output signal of each balun to a double-wall screen room, where the signals are attenuated, digitized (0.5-ns/sample, numerically compensated for cable losses, and numerically integrated. By contrast, each inner-MITL current monitor contains only a single B-dot sensor. These monitors are fielded in opposite-polarity pairs. The two

  17. Arterial pressure allows monitoring the changes in cardiac output induced by volume expansion but not by norepinephrine.

    Science.gov (United States)

    Monnet, Xavier; Letierce, Alexia; Hamzaoui, Olfa; Chemla, Denis; Anguel, Nadia; Osman, David; Richard, Christian; Teboul, Jean-Louis

    2011-06-01

    To evaluate to which extent the systemic arterial pulse pressure could be used as a surrogate of cardiac output for assessing the effects of a fluid challenge and of norepinephrine. Observational study. Medical intensive care unit. Patients with an acute circulatory failure who received a fluid challenge (228 patients, group 1) or in whom norepinephrine was introduced or increased (145 patients, group 2). We measured the systolic, diastolic, and mean arterial pressure, pulse pressure, and the transpulmonary thermodilution cardiac output before and after the therapeutic interventions. In group 1, the fluid challenge significantly increased cardiac output by 24% ± 25%. It significantly increased cardiac output by ≥15% (+35% ± 27%) in 142 patients ("responders"). The fluid-induced changes in cardiac output were correlated with the changes in pulse pressure (r = .56, p arterial pressure (r = .55, p arterial pressure (r = .37, p arterial pressure (r = .52, p pressure were significantly related to changes in stroke volume (multiple r = .52) and to age (r = .12). A fluid-induced increase in pulse pressure of ≥17% allowed detecting a fluid-induced increase in cardiac output of ≥15% with a sensitivity of 65[56-72]% and a specificity of 85[76-92]%. The area under the receiver operating characteristic curves for the fluid-induced changes in mean arterial pressure and in diastolic arterial pressure was significantly lower than for pulse pressure. In group 2, the introduction/increase of norepinephrine significantly increased cardiac output by 14% ± 18%. The changes in cardiac output induced by the introduction/increase in the dose of norepinephrine were correlated with the changes in pulse pressure and systolic arterial pressure (r = .21 and .29, respectively, p = .001) but to a significantly lesser extent than in group 1. Pulse pressure and systolic arterial pressure could be used for detecting the fluid-induced changes in cardiac output, in spite of a significant

  18. Uncertainty of solute flux estimation in ungauged small streams: potential implications for input-output nutrient mass balances at stream reach scale

    Directory of Open Access Journals (Sweden)

    A. Butturini

    2005-01-01

    Full Text Available Input-output mass balances within stream reaches provide in situ estimates of stream nutrient retention/release under a wide spectrum of hydrological conditions. Providing good estimates of the mass balances for nutrients depends on precise hydrological monitoring and good chemical characterisation of stream water at the input and output ends of the stream reach. There is a need to optimise the hydrological monitoring and the frequencies of water sampling to yield precise annual mass balances, so as to avoid undue cost - high resolution monitoring and subsequent chemical analysis can be labour intensive and costly. In this paper, simulation exercises were performed using a data set created to represent the instantaneous discharge and solute dynamics at the input and output ends of a model stream reach during a one year period. At the output end, stream discharge and water chemistry were monitored continuously, while the input end was assumed to be ungauged; water sampling frequency was changed arbitrarily. Instantaneous discharge at the ungauged sampling point was estimated with an empirical power model linking the discharge to the catchment area (Hooper, 1986. The model thus substitutes for the additional gauge station. Simulations showed that 10 days was the longest chemical sampling interval which could provide reach annual mass balances of acceptable precision. Presently, the relationship between discharge and catchment area is usually assumed to be linear but simulations indicate that small departures from the linearity of this relationship could cause dramatic changes in the mass balance estimations.

  19. A method to determine the input-output balances for nitrogen applied to the Lheebroekerzand integrated monitoring area (The Netherlands)

    NARCIS (Netherlands)

    Smit, H.M.C.

    1997-01-01

    The International Cooperative Programme on Integrated Monitoring on Air Pollution Effects (ICP/IM) monitors chemical and biological indicators at the level of catchment areas. The Dutch monitoring area is located at Lheebroekerzand (Province of Drenthe). Since this area is not a catchment, an altern

  20. Breeding for resistance to gastrointestinal nematodes - the potential in low-input/output small ruminant production systems.

    Science.gov (United States)

    Zvinorova, P I; Halimani, T E; Muchadeyi, F C; Matika, O; Riggio, V; Dzama, K

    2016-07-30

    The control of gastrointestinal nematodes (GIN) is mainly based on the use of drugs, grazing management, use of copper oxide wire particles and bioactive forages. Resistance to anthelmintic drugs in small ruminants is documented worldwide. Host genetic resistance to parasites, has been increasingly used as a complementary control strategy, along with the conventional intervention methods mentioned above. Genetic diversity in resistance to GIN has been well studied in experimental and commercial flocks in temperate climates and more developed economies. However, there are very few report outputs from the more extensive low-input/output smallholder systems in developing and emerging countries. Furthermore, results on quantitative trait loci (QTL) associated with nematode resistance from various studies have not always been consistent, mainly due to the different nematodes studied, different host breeds, ages, climates, natural infections versus artificial challenges, infection level at sampling periods, among others. The increasing use of genetic markers (Single Nucleotide Polymorphisms, SNPs) in GWAS or the use of whole genome sequence data and a plethora of analytic methods offer the potential to identify loci or regions associated nematode resistance. Genomic selection as a genome-wide level method overcomes the need to identify candidate genes. Benefits in genomic selection are now being realised in dairy cattle and sheep under commercial settings in the more advanced countries. However, despite the commercial benefits of using these tools, there are practical problems associated with incorporating the use of marker-assisted selection or genomic selection in low-input/output smallholder farming systems breeding schemes. Unlike anthelmintic resistance, there is no empirical evidence suggesting that nematodes will evolve rapidly in response to resistant hosts. The strategy of nematode control has evolved to a more practical manipulation of host-parasite equilibrium

  1. Crack Growth Monitoring in Harsh Environments by Electric Potential Measurements

    Energy Technology Data Exchange (ETDEWEB)

    Lloyd, Wilson Randolph; Reuter, Walter Graham; Weinberg, David Michael

    1999-09-01

    Electric potential measurement (EPM) technology offers an attractive alternative to conventional nondestructive evaluation (NDE) for monitoring crack growth in harsh environments. Where conventional NDE methods typically require localized human interaction, the EPM technique developed at the Idaho National Engineering and Environmental Laboratory (INEEL) can be operated remotely and automatically. Once a crack-like defect is discovered via conventional means, EPM can be applied to monitor local crack size changes. This is of particular interest in situations where an identified structural defect is not immediately rejectable from a fitness-for-service viewpoint, but due to operational and environmental conditions may grow to an unsafe size with continuing operation. If the location is in a harsh environment where periodic monitoring by normal means is either too costly or not possible, a very expensive repair may be immediately mandated. However, the proposed EPM methodology may offer a unique monitoring capability that would allow for continuing service. INEEL has developed this methodology, supporting equipment, and calibration information to apply EPM in a field environment for just this purpose. Laboratory and pilot scale tests on full-size engineering structures (pressure vessels and piping) have been successfully performed. The technique applicable is many severe environments because the sensitive equipment (electronics, operators) can be situated in a remote location, with only current and voltage probe electrical leads entering into the harsh environment. Experimental results showing the utility of the methodology are presented, and unique application concepts that have been examined by multiple experiments are discussed.

  2. Output beam energy measurement of a 100-MeV KOMAC drift tube linac by using a stripline beam position monitor

    Science.gov (United States)

    Kim, Han-Sung

    2015-10-01

    The 100-MeV proton linac at the KOMAC (Korea Multi-purpose Accelerator Complex) is composed of a 50-keV proton injector, a 3-MeV RFQ (radio-frequency quadrupole) and a 100-MeV DTL (drift tube linac). The proton beam is accelerated from 3 MeV to 100 MeV through 11 DTL tanks. The precise measurement of the proton-beam's energy at the output of each DTL tank is important for the longitudinal beam dynamics and can be performed by using a time-of-flight method with a BPM (beam position monitor), which is installed between each DTL tank. The details of the output beam energy measurement of the KOMAC DTL with stripline-type BPM and BPM signal processing, along with a comparison with the simulation results, will be presented in this paper.

  3. Potential for Integrating Community-Based Monitoring into REDD+

    Directory of Open Access Journals (Sweden)

    Arturo Balderas Torres

    2014-07-01

    Full Text Available Countries at the United Nations Framework on the Convention on Climate Change (UNFCCC have decided to engage local communities and indigenous groups into the activities for the monitoring, reporting and verification (MRV of the program to reduce emissions from deforestation and forest degradation and increase carbon removals (REDD+. Previous research and projects have shown that communities can produce reliable data on forest area and carbon estimates through field measurements. The objective of this article is to describe the framework that is being created for REDD+ under the UNFCCC to identify the potential inclusion of local information produced through community-based monitoring (CBM into monitoring systems for REDD+. National systems could use different sources of information from CBM: first, local information can be produced as part of public programs by increasing sample size of national or regional inventories; second, government can collect information to produce carbon estimates from on-going management practices implemented at local level driven by access to local direct benefits (e.g., forest management plans, watershed conservation; third, national data systems could include information from projects participating in carbon markets and other certification schemes; and finally information will be produced as part of the activities associated to the implementation of social and environmental safeguards. Locally generated data on carbon and areas under different forms of management can be dovetailed into national systems and be used to describe management practices, complement existing information or replace Tier 1/2 values with more detailed local data produced by CBM.

  4. Saliva: a potential media for disease diagnostics and monitoring.

    Science.gov (United States)

    Liu, Jingyi; Duan, Yixiang

    2012-07-01

    Within the past 10 years, the use of saliva as a diagnostic tool has gained considerable attention and become a well-accepted method. As a diagnostic fluid, saliva offers superiority over serum due to both a noninvasive collection method by specially trained persons and a cost-effective approach for screening of large populations. Collection of saliva offers a reduced risk of infection compared to the collection of serum. Moreover, obtaining saliva samples from infant, disabled or anxious patients, is much easier than obtaining other samples. There is a lot of useful components-changing information in saliva when a person is in sick. Therefore, we define these changing components as "biomarkers". The utilization of biomarkers as early predictors for clinical disease not only contributes to the effective prevention and treatment of diseases, but also enhances the assessment of potential health risks. In this article, we have reviewed the properties of saliva, the salivary analysis method for biomarker discovery, and the diagnostic potentials of salivary biomarkers in monitoring and detecting periodontal disease, Oral and Breast cancers, and Sjögren's syndrome. We also discussed some barriers of applications of saliva as a diagnostic media as well as recent improvements. We also prospected the future processing directions of using biomarkers in disease diagnosis and draw a conclusion that saliva is indeed an effective media in various disease monitoring and diagnosis.

  5. Self-Potential Monitoring for Geologic CO2 Sequestration

    Science.gov (United States)

    Nishi, Y.; Tosha, T.; Ishido, T.

    2009-12-01

    To appraise the utility of geophysical techniques for monitoring CO2 injected into aquifers, we carried out numerical simulations of an aquifer system underlying a portion of Tokyo Bay and calculated the temporal changes in geophysical observables caused by changing underground conditions as computed by the reservoir simulation. We used the STAR general-purpose reservoir simulator with the CO2SQS equation-of-state package (Pritchett, 2005) which treats three fluid phases (liquid- and gaseous-phase CO2 and an aqueous liquid phase) to calculate the evolution of reservoir conditions, and then used various “geophysical postprocessors” to calculate the resulting temporal changes in the earth-surface distributions of microgravity, apparent resistivity (from either DC or MT surveys), seismic observables and electrical self-potential (SP). The applicability of any particular method is likely to be highly site-specific, but these calculations indicate that none of these techniques should be ruled out altogether. In case of SP, CO2 injection does not create large electric signals through electrokinetic coupling within the saline aquifer owing to small coupling coefficients under the high salinity conditions. However, if a substantial pressure disturbance is induced to shallower levels where the interface between shallower fresh- and deeper saline-waters (which works as the boundary between regions of differing streaming potential coefficient) is present, obvious SP changes can appear on the ground surface. Continuous and/or repeat SP measurements are thought to be a promising geophysical technique to monitor pressure changes in shallower levels than the saline aquifer where CO2 is injected. In addition to SP measurements in a relatively wide area like covering the horizontal extent of CO2 plume, SP monitoring in a local area around a deep well is thought to be worthwhile from a different angle. SP anomalies of negative polarity are frequently observed near deep wells

  6. Online monitoring of Mezcal fermentation based on redox potential measurements.

    Science.gov (United States)

    Escalante-Minakata, P; Ibarra-Junquera, V; Rosu, H C; De León-Rodríguez, A; González-García, R

    2009-01-01

    We describe an algorithm for the continuous monitoring of the biomass and ethanol concentrations as well as the growth rate in the Mezcal fermentation process. The algorithm performs its task having available only the online measurements of the redox potential. The procedure combines an artificial neural network (ANN) that relates the redox potential to the ethanol and biomass concentrations with a nonlinear observer-based algorithm that uses the ANN biomass estimations to infer the growth rate of this fermentation process. The results show that the redox potential is a valuable indicator of the metabolic activity of the microorganisms during Mezcal fermentation. In addition, the estimated growth rate can be considered as a direct evidence of the presence of mixed culture growth in the process. Usually, mixtures of microorganisms could be intuitively clear in this kind of processes; however, the total biomass data do not provide definite evidence by themselves. In this paper, the detailed design of the software sensor as well as its experimental application is presented at the laboratory level.

  7. Potential biomarkers for monitoring therapeutic response in patients with CIDP.

    Science.gov (United States)

    Dalakas, Marinos C

    2011-06-01

    Although the majority of patients with CIDP variably respond to intravenous immunoglobulin (IVIg), steroids, or plasmapheresis, 30% of them are unresponsive or insufficiently responsive to these therapies. The heterogeneity in therapeutic responses necessitates the need to search for biomarkers to determine the most suitable therapy from the outset and explore the best means for monitoring disease activity. The ICE study, which led to the first FDA-approved indication for IVIg in CIDP, has shown that maintenance therapy prevents relapses and axonal loss. In this paper, the multiple actions exerted by IVIg on the immunoregulatory network of CIDP are discussed as potential predictors of response to therapies. Emerging molecular markers, promising in identifying responders to IVIg from non-responders, include modulation of FcγRIIB receptors on monocytes and genome-wide transcription studies related to inflammatory mediators, demyelination, or axonal degeneration. Skin biopsies, Peripheral Blood Lymhocytes, CSF, and sera are accessible surrogate tissues for further exploring these molecules during therapies.

  8. Arterial pressure-based cardiac output monitoring: a multicenter validation of the third-generation software in septic patients.

    Science.gov (United States)

    De Backer, Daniel; Marx, Gernot; Tan, Andrew; Junker, Christopher; Van Nuffelen, Marc; Hüter, Lars; Ching, Willy; Michard, Frédéric; Vincent, Jean-Louis

    2011-02-01

    Second-generation FloTrac software has been shown to reliably measure cardiac output (CO) in cardiac surgical patients. However, concerns have been raised regarding its accuracy in vasoplegic states. The aim of the present multicenter study was to investigate the accuracy of the third-generation software in patients with sepsis, particularly when total systemic vascular resistance (TSVR) is low. Fifty-eight septic patients were included in this prospective observational study in four university-affiliated ICUs. Reference CO was measured by bolus pulmonary thermodilution (iCO) using 3-5 cold saline boluses. Simultaneously, CO was computed from the arterial pressure curve recorded on a computer using the second-generation (CO(G2)) and third-generation (CO(G3)) FloTrac software. CO was also measured by semi-continuous pulmonary thermodilution (CCO). A total of 401 simultaneous measurements of iCO, CO(G2), CO(G3), and CCO were recorded. The mean (95%CI) biases between CO(G2) and iCO, CO(G3) and iCO, and CCO and iCO were -10 (-15 to -5)% [-0.8 (-1.1 to -0.4) L/min], 0 (-4 to 4)% [0 (-0.3 to 0.3) L/min], and 9 (6-13)% [0.7 (0.5-1.0) L/min], respectively. The percentage errors were 29 (20-37)% for CO(G2), 30 (24-37)% for CO(G3), and 28 (22-34)% for CCO. The difference between iCO and CO(G2) was significantly correlated with TSVR (r(2) = 0.37, p iCO and CO(G3). In patients with sepsis, the third-generation FloTrac software is more accurate, as precise, and less influenced by TSVR than the second-generation software.

  9. Continuous monitoring of electromyography (EMG), mechanomyography (MMG), sonomyography (SMG) and torque output during ramp and step isometric contractions.

    Science.gov (United States)

    Guo, Jing-Yi; Zheng, Yong-Ping; Xie, Hong-Bo; Chen, Xin

    2010-11-01

    In this study we simultaneously collected ultrasound images, EMG, MMG from the rectus femoris (RF) muscle and torque signal from the leg extensor muscle group of nine male subjects (mean±SD, age=30.7±.4.9 years; body weight=67.0±8.4kg; height=170.4±6.9cm) during step, ramp increasing, and decreasing at three different rates (50%, 25% and 17% MVC/s). The muscle architectural parameters extracted from ultrasound imaging, which reflect muscle contractions, were defined as sonomyography (SMG) in this study. The cross-sectional area (CSA) and aspect ratio between muscle width and thickness (width/thickness) were extracted from ultrasound images. The results showed that the CSA of RF muscles decreased by 7.25±4.07% when muscle torque output changed from 0% to 90% MVC, and the aspect ratio decreased by 41.66±7.96%. The muscle contraction level and SMG data were strongly correlated (R(2)=0.961, P=0.003, for CSA and R(2)=0.999, PEMG RMS in ramp increasing was 8.25±4.00% higher than step (P=0.002). The normalized MMG RMS of step contraction was significantly lower than ramp increasing and decreasing, with averaged differences of 12.22±3.37% (P=0.001) and 12.06±3.37% (P=0.001), respectively. The results of this study demonstrated that the CSA and aspect ratio, i.e., SMG signals, can provide useful information about muscle contractions. They may therefore complement EMG and MMG for studying muscle activation strategies under different conditions.

  10. Potentials of satellite imagery for monitoring arctic goose productivity

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This paper reports upon the exciting possibility that satellite imagery may now provide feasible means for grossly monitoring arctic habitat conditions in a timely...

  11. Noninvasive cardiac output monitoring during exercise testing: Nexfin pulse contour analysis compared to an inert gas rebreathing method and respired gas analysis.

    Science.gov (United States)

    Bartels, Sebastiaan A; Stok, Wim J; Bezemer, Rick; Boksem, Remco J; van Goudoever, Jeroen; Cherpanath, Thomas G V; van Lieshout, Johannes J; Westerhof, Berend E; Karemaker, John M; Ince, Can

    2011-10-01

    Exercise testing is often used to assess cardiac function during physical exertion to obtain diagnostic information. However, this procedure is limited to measuring the electrical activity of the heart using electrocardiography and intermittent blood pressure (BP) measurements and does not involve the continuous assessment of heart functioning. In this study, we compared continuous beat-to-beat pulse contour analysis to monitor noninvasive cardiac output (CO) during exercise with inert gas rebreathing and respired gas analysis. Nineteen healthy male volunteers were subjected to bicycle ergometry testing with increasing workloads. Cardiac output was deter- mined noninvasively by continuous beat-to-beat pulse contour analysis (Nexfin) and by inert gas rebreathing, and estimated using the respired gas analysis method. The effects of the rebreathing maneuver on heart rate (HR), stroke volume (SV), and CO were evaluated. The CO values derived from the Nexfin- and inert gas rebreathing methods were well correlated (r = 0.88, P gas analysis-derived CO values correlated even better (r = 0.94, P < 0.01) and the limits of agreement were 21.5% with a measurement bias of -0.70 ± 1.6 L/min. At rest, the rebreathing maneuver increased HR by 13 beats/min (P < 0.01), SV remained unaffected (P = 0.7), while CO increased by 1.0 L/min (P < 0.01). Rebreathing did not affect these parameters during exercise. Nexfin continuous beat-to-beat pulse contour analysis is an appropriate method for noninvasive assessment of CO during exercise.

  12. Monitoring of flash visual evoked potentials during neurosurgical operations.

    Science.gov (United States)

    Cedzich, C; Schramm, J

    1990-01-01

    In summary, our results suggest that flash VEP monitoring is not specific for visual acuity and has not proved helpful as an intraoperative warning system. The future challenge will be to devise a method which activates only those fibers specific to visual acuity and which provides reproducible and reliable information quickly enough that adjustments in patient management can be made.

  13. Multisite Tissue Oxygenation Monitoring Indicates Organ-Specific Flow Distribution and Oxygen Delivery Related to Low Cardiac Output in Preterm Infants With Clinical Sepsis

    NARCIS (Netherlands)

    van der Laan, Michelle E.; Roofthooft, Marcus T. R.; Fries, Marian W. A.; Schat, Trijntje E.; Bos, Arend F.; Berger, Rolf M. F.; Kooi, Elisabeth M. W.

    Objectives: Cardiac output may be compromised in preterm infants with sepsis. Whether low cardiac output is associated with low tissue oxygen supply in these patients is unclear. The aim of the current study was to assess the association between cardiac output, assessed by echocardiography, and

  14. Multisite Tissue Oxygenation Monitoring Indicates Organ-Specific Flow Distribution and Oxygen Delivery Related to Low Cardiac Output in Preterm Infants With Clinical Sepsis

    NARCIS (Netherlands)

    van der Laan, Michelle E.; Roofthooft, Marcus T. R.; Fries, Marian W. A.; Schat, Trijntje E.; Bos, Arend F.; Berger, Rolf M. F.; Kooi, Elisabeth M. W.

    2016-01-01

    Objectives: Cardiac output may be compromised in preterm infants with sepsis. Whether low cardiac output is associated with low tissue oxygen supply in these patients is unclear. The aim of the current study was to assess the association between cardiac output, assessed by echocardiography, and tiss

  15. Standard and limitation of intraoperative monitoring of the visual evoked potential

    OpenAIRE

    2010-01-01

    Visual evoked potential (VEP) has been installed as one of the intraoperative visual function monitoring. It remains unclear, however, whether intraoperative VEP monitoring facilitates as a real time visual function monitoring with satisfactory effectiveness and sensitivity. To evaluate this, relationships between VEP waveform changes and postoperative visual function were analysed retrospectively. Intraoperative VEP monitoring was carried out for 106 sides (eyes) in 53 surgeries, including t...

  16. First measurements of gas output from bubbling pools in a mud volcano at the periphery of Mt Etna (Italy): methodologies and implications for monitoring purposes

    Science.gov (United States)

    Federico, Cinzia; Giudice, Gaetano; Liuzzo, Marco; Pedone, Maria; Cosenza, Paolo; Riccobono, Giuseppe

    2014-05-01

    angles. The positions of both laser source and retro-reflectors were chosen so to have the target CO2 plume in between retro-reflectors and the GasFinder, and to realize the complete coverage of the degassing area. We therefore explored the possibility to combine the available path-integrated CO2 concentration data to derive a two-dimensional mapping of CO2 over the mud volcano. The periodic survey of total CO2 output in a subset of vigorously degassing pools, paralleled to the chemical and isotopic measurements routinely performed in selected pools, would offer a robust monitoring tool in a peripheral sector of the volcano. Chiodini G., D'Alessandro W. and Parello F. (1996) Geochemistry of gases and water discharged by the mud volcanoes at Paternò, Mt. Etna (Italy). Bull. Volcanol. 58, 51-58. Paonita A., Caracausi A., Iacono-Marziano G., Martelli M., Rizzo A. (2012) Geochemical evidence for mixing between fluids exsolved at different depths in the magmatic system of Mt Etna (Italy). Geochim. Cosmochim. Acta 84 (2012) 380-394.

  17. Optoelectronic methods in potential application in monitoring of environmental conditions

    Science.gov (United States)

    Mularczyk-Oliwa, Monika; Bombalska, Aneta; Kwaśny, Mirosław; Kopczyński, Krzysztof; Włodarski, Maksymilian; Kaliszewski, Miron; Kostecki, Jerzy

    2016-12-01

    Allergic rhinitis, also known as hay fever is a type of inflammation which occurs when the immune system overreacts to allergens in the air. It became the most common disease among people. It became important to monitor air content for the presence of a particular type of allergen. For the purposes of environmental monitoring there is a need to widen the group of traditional methods of identification of pollen for faster and more accurate research systems. The aim of the work was the characterization and classification of certain types of plant pollens by using laser optical methods, which were supported by the chemmometrics. Several species of pollen were examined, for which a database of spectral characteristics was created, using LIF, Raman scattering and FTIR methods. Spectral database contains characteristics of both common allergens and pollen of minor importance. Based on registered spectra, statistical analysis was made, which allows the classification of the tested pollen species. For the study of the emission spectra Nd:YAG laser was used with the fourth harmonic generation (266 nm) and GaN diode laser (375 nm). For Raman scattering spectra spectrometer Nicolet IS-50 with a excitation wavelength of 1064 nm was used. The FTIR spectra, recorded in the mid infrared1 range (4000-650 cm-1) were collected with use of transmission mode (KBr pellet), ATR and DRIFT.

  18. Potential to monitor plant stress using remote sensing tools

    CSIR Research Space (South Africa)

    Ramoelo, Abel

    2014-01-01

    Full Text Available tourism is a major source of livelihood. In this study we evaluated the spatio e temporal distribution plant status during wet and dry seasons using two measures of plant stress namely the midday leaf water potential (LWP), and leaf nitrogen (N...

  19. Calibrated versus uncalibrated arterial pressure waveform analysis in monitoring cardiac output with transpulmonary thermodilution in patients with severe sepsis and septic shock: an observational study.

    Science.gov (United States)

    Slagt, Cornelis; Helmi, Mochamat; Malagon, Ignacio; Groeneveld, A B Johan

    2015-01-01

    Cardiac output (CO) measurement is often required in critically ill patients. The performances of newer, less invasive techniques require evaluation in patients with severe sepsis and septic shock. To compare calibrated arterial pressure waveform analysis-derived CO (COap, VolumeView/EV1000) and the uncalibrated form (COfv, FloTrac/Vigileo) with transpulmonary thermodilution derived CO (COtptd). A prospective, observational, single-centre study. ICU of a general teaching hospital. Twenty consecutive patients with severe sepsis or septic shock requiring haemodynamic monitoring by VolumeView/EV1000 and receiving mechanical ventilation. Connection of FloTrac/Vigileo to radial artery catheter already in situ. Radial (COfv) and femoral (COap) arterial waveform-derived CO measurements were compared with COtptd with respect to bias, precision, limits of agreement and percentage error, and the percentage error in the course of time since the last calibration of COap by COtptd. In comparing COap with COtptd (n = 267 paired measurements), the bias was 0.02 and limits of agreement were -2.49 to 2.52 l min, with a percentage error of 31%. The percentage error between COap and COtptd remained less than 30% until 8 h after calibration. In comparing COfv with COtptd (n = 301), the bias was -0.86 l min and limits of agreement were -4.48 to 2.77 l min, with a percentage error of 48%. The biases of COap and COfv correlated with systemic vascular resistance [r = 0.13 (P = 0.029) and r = 0.42 (P arterial waveform analysis technique. Compared with the uncalibrated COfv, the recently introduced calibrated arterial pressure waveform analysis-derived COap was more accurate and less dependent on vascular tone for up to 8 hours after callibation when monitoring CO in patients with severe sepsis and septic shock. The COap and COfv methods have poor to moderate CO-tracking abilities.

  20. POTENTIAL OF UAV BASED CONVERGENT PHOTOGRAMMETRY IN MONITORING REGENERATION STANDARDS

    Directory of Open Access Journals (Sweden)

    U. Vepakomma

    2015-08-01

    Full Text Available Several thousand hectares of forest blocks are regenerating after harvest in Canada. Monitoring their performance over different stages of growth is critical in ensuring future productivity and ecological balance. Tools for rapid evaluation can support timely and reliable planning of interventions. Conventional ground surveys or visual image assessments are either time intensive or inaccurate, while alternate operational remote sensing tools are unavailable. In this study, we test the feasibility and strength of UAV-based photogrammetry with an EO camera on a UAV platform in assessing regeneration performance. Specifically we evaluated stocking, spatial density and height distribution of naturally growing (irregularly spaced stems or planted (regularly spaced stems conifer regeneration in different phases of growth. Standard photogrammetric workflow was applied on the 785 acquired images for 3D reconstruction of the study sites. The required parameters were derived based on automated single stem detection algorithm developed in-house. Comparing with field survey data, preliminary results hold promise. Future studies are planned to expand the scope to larger areas and different stand conditions.

  1. 5-HT4-receptors modulate induction of long-term depression but not potentiation at hippocampal output synapses in acute rat brain slices.

    Directory of Open Access Journals (Sweden)

    Matthias Wawra

    Full Text Available The subiculum is the principal target of CA1 pyramidal cells and mediates hippocampal output to various cortical and subcortical regions of the brain. The majority of subicular pyramidal cells are burst-spiking neurons. Previous studies indicated that high frequency stimulation in subicular burst-spiking cells causes presynaptic NMDA-receptor dependent long-term potentiation (LTP whereas low frequency stimulation induces postsynaptic NMDA-receptor-dependent long-term depression (LTD. In the present study, we investigate the effect of 5-hydroxytryptamine type 4 (5-HT4 receptor activation and blockade on both forms of synaptic plasticity in burst-spiking cells. We demonstrate that neither activation nor block of 5-HT4 receptors modulate the induction or expression of LTP. In contrast, activation of 5-HT4 receptors facilitates expression of LTD, and block of the 5-HT4 receptor prevents induction of short-term depression and LTD. As 5-HT4 receptors are positively coupled to adenylate cyclase 1 (AC1, 5-HT4 receptors might modulate PKA activity through AC1. Since LTD is blocked in the presence of 5-HT4 receptor antagonists, our data are consistent with 5-HT4 receptor activation by ambient serotonin or intrinsically active 5-HT4 receptors. Our findings provide new insight into aminergic modulation of hippocampal output.

  2. Combined monitoring of evoked potentials during microsurgery for lesions adjacent to the brainstem and intracranial aneurysms

    Institute of Scientific and Technical Information of China (English)

    KANG De-zhi; WU Zan-yi; LAN Qing; YU Liang-hong; LIN Zhang-ya; WANG Chen-yang; LIN Yuan-xiang

    2007-01-01

    Background Neurophysiologic monitoring during surgery is to prevent permanent neurological injury resulting from surgical manipulation. To improve the accuracy and sensitivity of intraoperative neuromonitoring, combined monitoring of transcranial electrical stimulation motor evoked potentials (TES-MEPs), somatosensory evoked potentials (SSEPs) and brainstem auditory evoked potentials (BAEPs) was attempted in microsurgery for lesions adjacent to the brainstem and intracranial aneurysms.Methods Monitoring of combined TES-MEPs with SSEPs was attempted in 68 consecutive patients with lesions adjacent to the brainstem as well as intracranial aneurysms. Among them, 31 patients (31 operations, 28 of posterior cranial fossa tumors, 3 of posterior circulation aneurysms) were also subjected to monitoring of BAEPs. The correlation of monitoring results and clinical outcome was studied prospectively.Results Combined monitoring of evoked potentials (EPs) was done in 64 (94.1%) of the 68 patients. MEPs monitoring was impossible for 4 patients (5.9%). No complication was observed during the combined monitoring in all the patients. In 45 (66.2%) of the 68 patients, EPs were stable, and they were neurologically intact. Motor dysfunction was detected by MEPs in 8 patients, SSEPs in 5, and BAEPs in 4, respectively.Conclusions A close relationship exists between postoperative motor function and the results of TES-MEPs monitoring.TES-MEPs are superior to SSEPs and BAEPs in detecting motor dysfunction, but combined EPs serve as a safe,effective and invasive method for intraoperative monitoring of the function of the motor nervous system. Monitoring of combined EPs during microsurgery for lesions adjacent to the brainstem and intracranial aneurysms may detect potentially hazardous maneuvers and improve the safety of subsequent procedures.

  3. Monitoring Potential Transport of Radioactive Contaminants in Shallow Ephemeral Channels

    Energy Technology Data Exchange (ETDEWEB)

    Miller, Julianne J.; Mizell, Steve A.; Nikolich, George; Campbell, Scott A.

    2012-02-01

    The U.S. Department of Energy (DOE) National Nuclear Security Administration (NNSA), Nevada Site Office (NSO), Environmental Restoration Soils Activity has authorized the Desert Research Institute (DRI) to conduct field assessments of potential sediment transport of contaminated soil from Corrective Action Unit (CAU) 550, Area 8 Smoky Contamination Area (CA), during precipitation runoff events. CAU 550 includes Corrective Action Sites (CASs) 08-23-03, 08-23-04, 08-23-06, and 08-23-07; these CASs are associated with tests designated Ceres, Smoky, Oberon, and Titania, respectively.

  4. Technology transfer potential of an automated water monitoring system. [market research

    Science.gov (United States)

    Jamieson, W. M.; Hillman, M. E. D.; Eischen, M. A.; Stilwell, J. M.

    1976-01-01

    The nature and characteristics of the potential economic need (markets) for a highly integrated water quality monitoring system were investigated. The technological, institutional and marketing factors that would influence the transfer and adoption of an automated system were studied for application to public and private water supply, public and private wastewater treatment and environmental monitoring of rivers and lakes.

  5. CEP biomarkers as potential tools for monitoring therapeutics.

    Directory of Open Access Journals (Sweden)

    Kutralanathan Renganathan

    Full Text Available BACKGROUND: Carboxyethylpyrrole (CEP adducts are oxidative modifications derived from docosahexaenoate-containing lipids that are elevated in ocular tissues and plasma in age-related macular degeneration (AMD and in rodents exposed to intense light. The goal of this study was to determine whether light-induced CEP adducts and autoantibodies are modulated by pretreatment with AL-8309A under conditions that prevent photo-oxidative damage of rat retina. AL-8309A is a serotonin 5-HT1A receptor agonist. METHODS: Albino rats were dark adapted prior to blue light exposure. Control rats were maintained in normal cyclic light. Rats were injected subcutaneously 3x with 10 mg/kg AL-8309A (2 days, 1 day and 0 hours before light exposure for 6 h (3.1 mW/cm(2, λ=450 nm. Animals were sacrificed immediately following light exposure and eyes, retinas and plasma were collected. CEP adducts and autoantibodies were quantified by Western analysis or ELISA. RESULTS: ANOVA supported significant differences in mean amounts of CEP adducts and autoantibodies among the light + vehicle, light + drug and dark control groups from both retina and plasma. Light-induced CEP adducts in retina were reduced ~20% following pretreatment with AL-8309A (n = 62 rats, p = 0.006 and retinal CEP immunoreactivity was less intense by immunohistochemistry. Plasma levels of light-induced CEP adducts were reduced at least 30% (n = 15 rats, p = 0.004 by drug pretreatment. Following drug treatment, average CEP autoantibody titer in light exposed rats (n = 22 was unchanged from dark control levels, and ~20% (p = 0.046 lower than in vehicle-treated rats. CONCLUSIONS: Light-induced CEP adducts in rat retina and plasma were significantly decreased by pretreatment with AL-8309A. These results are consistent with and extend previous studies showing AL-8309A reduces light-induced retinal lesions in rats and support CEP biomarkers as possible tools for monitoring the efficacy of select therapeutics.

  6. Awareness during anaesthesia for surgery requiring evoked potential monitoring: A pilot study

    Directory of Open Access Journals (Sweden)

    Pritish J Korula

    2017-01-01

    Full Text Available Background: Evoked potential monitoring such as somatosensory-evoked potential (SSEP or motor-evoked potential (MEP monitoring during surgical procedures in proximity to the spinal cord requires minimising the minimum alveolar concentrations (MACs below the anaesthetic concentrations normally required (1 MAC to prevent interference in amplitude and latency of evoked potentials. This could result in awareness. Our primary objective was to determine the incidence of awareness while administering low MAC inhalational anaesthetics for these unique procedures. The secondary objective was to assess the adequacy of our anaesthetic technique from neurophysiologist′s perspective. Methods: In this prospective observational pilot study, 61 American Society of Anesthesiologists 1 and 2 patients undergoing spinal surgery for whom intraoperative evoked potential monitoring was performed were included; during the maintenance phase, 0.7-0.8 MAC of isoflurane was targeted. We evaluated the intraoperative depth of anaesthesia using a bispectral (BIS index monitor as well as the patients response to surgical stimulus (PRST scoring system. Post-operatively, a modified Bruce questionnaire was used to verify awareness. The adequacy of evoked potential readings was also assessed. Results: Of the 61 patients, no patient had explicit awareness. Intraoperatively, 19 of 61 patients had a BIS value of above sixty at least once, during surgery. There was no correlation with PRST scoring and BIS during surgery. Fifty-four out of 61 patient′s evoked potential readings were deemed ′good′ or ′fair′ for the conduct of electrophysiological monitoring. Conclusions: This pilot study demonstrates that administering low MAC inhalational anaesthetics to facilitate evoked potential monitoring does not result in explicit awareness. However, larger studies are needed to verify this. The conduct of SSEP electrophysiological monitoring was satisfactory with the use of this

  7. Agency attribution: event-related potentials and outcome monitoring.

    Science.gov (United States)

    Bednark, Jeffery G; Franz, Elizabeth A

    2014-04-01

    Knowledge about the effects of our actions is an underlying feature of voluntary behavior. Given the importance of identifying the outcomes of our actions, it has been proposed that the sensory outcomes of self-made actions are inherently different from those of externally caused outcomes. Thus, the outcomes of self-made actions are likely to be more motivationally significant for an agent. We used event-related potentials to investigate the relationship between the perceived motivational significance of an outcome and the attribution of agency in the presence of others. In our experiment, we assessed agency attribution in the presence of another agent by varying the degree of contiguity between participants' self-made actions and the sensory outcome. Specifically, we assessed the feedback correct-related positivity (fCRP) and the novelty P3 measures of an outcome's motivational significance and unexpectedness, respectively. Results revealed that both the fCRP and participants' agency attributions were significantly influenced by action-outcome contiguity. However, when action-outcome contiguity was ambiguous, novelty P3 amplitude was a reliable indicator of agency attribution. Prior agency attributions were also found to influence attribution in trials with ambiguous and low action-outcome contiguity. Participants' use of multiple cues to determine agency is consistent with the cue integration theory of agency. In addition to these novel findings, this study supports growing evidence suggesting that reinforcement processes play a significant role in the sense of agency.

  8. Remote real-time monitoring soil water potential system based on GSM

    Institute of Scientific and Technical Information of China (English)

    Yongming Zhao; Xin Lu; Haijiang Wang

    2008-01-01

    Aiming at the limitation of traditional measuring soil water potential, the paper presents an information system based GSM to real-time monitor data coming from multiple data sources. The monitoring system, which consisted of monitoring center, GSM transmission channel and data detection terminal, was given. The detection terminal included the measuring station and TS-2 negative pressure meter, which was applied to measure soil water potential. Nowadays the system has been successfully applied to drip irrigation in the cotton field on farm in Xinjiang region. The system provides a feasible technology frame-work for collecting and processing wide geographical distribution data in farmland.

  9. Spatiotemporal Variability in Potential Evapotranspiration across an Urban Monitoring Network

    Science.gov (United States)

    Miller, G. R.; Long, M. R.; Fipps, G.; Swanson, C.; Traore, S.

    2015-12-01

    Evapotranspiration in urban and peri-urban environments is difficult to measure and predict. Barriers to accurate assessment include: the wide range of microclimates caused by urban canyons, heat islands, and park cooling; limited instrument fetch; and the patchwork of native soils, engineered soils, and hardscape. These issues combine to make an accurate assessment of the urban water balance difficult, as evapotranspiration calculations require accurate meteorological data. This study examines nearly three years of data collected by a network of 18 weather stations in Dallas, Texas, designed to measure potential evapotranspiration (ETo) in support of the WaterMyYard conservation program (http://WaterMyYard.org). Variability amongst stations peaked during the summer irrigation months, with a maximum standard deviation of 0.3 mm/hr and 4 mm/d. However, we found a significant degree of information overlap in the network. Most stations had a high correlation (>0.75) with at least one other station in the network, and many had a high correlation with at least 10 others. Correlation strength between station ETo measurements did not necessarily decrease with Euclidean distance, as expected, but was more closely related to differences in station elevation and longitude. Stations that had low correlations with others in the network typically had siting and fetch issues. ETo showed a strong temporal persistence; average station autocorrelation was 0.79 at a 1-hour lag and 0.70 at a 24-hour lag. To supplement the larger-scale network data, we deployed a mobile, vehicle-mounted weather station to quantify deviations present in the atmospheric drivers of evapotranspiration: temperature, humidity, wind, and solar radiation. Data were collected at mid-day during the irrigation season. We found differences in mobile and station ETo predictions up to 0.2 mm/hr, primarily driven by wind speed variations. These results suggest that ETo variation at the neighborhood to municipality

  10. 连续多普勒无创血液动力学监测仪(USCOM)在危重患者中的运用%The Application of Ultrasonic Cardiac Output Monitor In the Critically Ill Patients

    Institute of Scientific and Technical Information of China (English)

    杨勤; 向明芳

    2012-01-01

    Objective: To compare the cardiac output detected by ultrasonic cardiac output monitor(USCOM) and Thoracic Electrical Bioimpedance(TEB). Methods: The cardiac outputs of 40 critically ill patients were detected by USCOM and TEB simultaneously. Results: There was no significant difference of the cardiac output detected by USCOM and TEB(P>0.10), the correlation analysis showed a positive correlation between cardiac output measured with USCOM and TEB(correlation coefficient of CO: r=0.8427, correlation coefficient of SV: r=0.8392, P0.10);且两种监测方法测得的结果具有正相关性(CO相关系数 r=0.8427,SV相关系数 r=0.8392,P均<0.01).结论采用USCOM技术监测危重患者的心输出量具有无创、连续、简便、准确的特点.

  11. Visual evoked potentials monitoring in a case of transient post-operative visual loss

    Directory of Open Access Journals (Sweden)

    Marie Capon

    2016-01-01

    Full Text Available Post-operative visual loss (POVL is a rare, albeit potentially serious complication of general anaesthesia. This report describes the case of a 54-year-old woman who developed transient POVL after general anaesthesia following a left posterior parietal meningioma surgery in the prone position and discusses the usefulness of visual evoked potentials monitoring in such situations.

  12. The potential use of domestic safeguards interior monitors in International Safeguards

    Energy Technology Data Exchange (ETDEWEB)

    Williams, J.D.; Dupree, S.A. [Sandia National Labs., Albuquerque, NM (United States); Sonnier, C.S. [Jupiter Corp., Albuquerque, NM (United States)

    1998-08-01

    An important future element of International Safeguards instrumentation is expected to be the merging of containment/surveillance and nondestructive assay equipment with domestic physical protection equipment into integrated systems, coupled with remote monitoring. Instrumentation would include interior monitoring and assessment and entry/exit monitoring. Of particular importance is the application of interior monitors in spaces of declared inactivity; for example, in nuclear material storage locations that are entered infrequently. The use of modern interior monitors in International Safeguards offers potential for improving effectiveness and efficiency. Within the context of increased cooperation, one can readily envision increased interaction between International Safeguards and Domestic Safeguards, including increased joint use of State System of Accounting and Control data.

  13. Potential of the TROPOspheric Monitoring Instrument (TROPOMI onboard the Sentinel-5 Precursor for the monitoring of terrestrial chlorophyll fluorescence

    Directory of Open Access Journals (Sweden)

    L. Guanter

    2014-12-01

    photosynthetic functioning of terrestrial ecosystems. The feasibility of SIF retrievals from spaceborne atmospheric spectrometers has been demonstrated by a number of studies in the last years. In this work, we investigate the potential of the upcoming TROPOspheric Monitoring Instrument (TROPOMI onboard the Sentinel-5 Precursor satellite mission for SIF retrieval. TROPOMI will sample the 675–775 nm spectral window with a spectral resolution of 0.5 nm and a pixel size of 7 km × 7 km. We use an extensive set of simulated TROPOMI data in order to assess the uncertainty of single SIF retrievals and subsequent spatio-temporal composites. Our results illustrate the enormous improvement in SIF monitoring achievable with TROPOMI with respect to comparable spectrometers currently in-flight, such as the Global Ozone Monitoring Experiment-2 (GOME-2 instrument. We find that TROPOMI can reduce global uncertainties in SIF mapping by more than a factor 2 with respect to GOME-2, which comes together with an about 5-fold improvement in spatial sampling. Finally, we discuss the potential of TROPOMI to accurately map other important vegetation parameters, such as leaf photosynthetic pigments and proxies for canopy structure, which will complement SIF retrievals for a self-contained description of vegetation condition and functioning.

  14. Potential of Multi-temporal InSAR Techniques for Bridges and Dams Monitoring

    OpenAIRE

    Sousa, Joaquim J.; Hlavá¿?ová, Ivana; Bakon, M; Patrício, G.; Guimarães, P.; Ruiz, Antonio M.; L. Bastos; Sousa, A; Bento, R.

    2014-01-01

    The aim of this paper is twofold. Firstly, to present a survey of the actual and most advanced methods for man-made structures monitoring, more specifically dams and bridges. Theoretical and technical aspects of these methodologies are presented and discussed focusing on innovative inspection methods and on the opportunities that could deliver. Secondly, to identify the opportunities that could potentially improve the inspections and maintenance processes, being the satellite-based monitoring...

  15. Calibrated versus uncalibrated arterial pressure waveform analysis in monitoring cardiac output with transpulmonary thermodilution in patients with severe sepsis and septic shock: an observational study

    NARCIS (Netherlands)

    Slagt, C.; Helmi, M.; Malagon, I.; Groeneveld, A.B.

    2015-01-01

    BACKGROUND: Cardiac output (CO) measurement is often required in critically ill patients. The performances of newer, less invasive techniques require evaluation in patients with severe sepsis and septic shock. OBJECTIVES: To compare calibrated arterial pressure waveform analysis-derived CO (COap, Vo

  16. Calibrated versus uncalibrated arterial pressure waveform analysis in monitoring cardiac output with transpulmonary thermodilution in patients with severe sepsis and septic shock: an observational study

    NARCIS (Netherlands)

    Slagt, C.; Helmi, M.; Malagon, I.; Groeneveld, A.B.

    2015-01-01

    BACKGROUND: Cardiac output (CO) measurement is often required in critically ill patients. The performances of newer, less invasive techniques require evaluation in patients with severe sepsis and septic shock. OBJECTIVES: To compare calibrated arterial pressure waveform analysis-derived CO (COap,

  17. Calibrated versus uncalibrated arterial pressure waveform analysis in monitoring cardiac output with transpulmonary thermodilution in patients with severe sepsis and septic shock: an observational study

    NARCIS (Netherlands)

    Slagt, C.; Helmi, M.; Malagon, I.; Groeneveld, A.B.

    2015-01-01

    BACKGROUND: Cardiac output (CO) measurement is often required in critically ill patients. The performances of newer, less invasive techniques require evaluation in patients with severe sepsis and septic shock. OBJECTIVES: To compare calibrated arterial pressure waveform analysis-derived CO (COap, Vo

  18. Performance monitoring in autism spectrum disorders: A systematic literature review of event-related potential studies.

    Science.gov (United States)

    Hüpen, Philippa; Groen, Yvonne; Gaastra, Geraldina F; Tucha, Lara; Tucha, Oliver

    2016-04-01

    Autism spectrum disorder (ASD) is marked by impairments in social-emotional situations, executive functioning, and behavioral regulation. These symptoms may be related to deficits in performance monitoring, i.e., the ability to observe and evaluate one's own behavior and performance which is necessary for the regulation of future behavior. The present literature review investigated electroencephalic correlates of performance monitoring in ASD. Event-related potentials (ERPs) considered in this review included internal performance monitoring components (error-related negativity, error positivity), external performance monitoring components (feedback-related negativity, feedback-P3), and observational performance monitoring components (observer error-related negativity, observer feedback-related negativity). The majority of studies point to reduced internal performance monitoring in ASD. External performance monitoring in reward-processing paradigms, where rewards are independent of performance, seems to be intact in ASD. So far, no studies have investigated the observer error-related negativity in ASD. Available data on the observer feedback-related negativity are inconclusive, since only two studies with differential study results investigated this construct in ASD. In general, results suggest that individuals with ASD have problems with internal performance monitoring and with learning from external, abstract feedback. In contrast, the processing of external, concrete feedback seems to be largely intact in ASD.

  19. Value of somatosensory evoked potentials in diagnosis, surgical monitoring and prognosis of cervical spondylotic myelopathy

    Institute of Scientific and Technical Information of China (English)

    DING Yu; HU Yong; RUAN Di-ke; CHEN Bo

    2008-01-01

    Background The value of somatosensory evoked potentials (SEPs) in the diagnosis and prognosis of cervical spondylotic myelopathy, as well as the usefulness of monitoring intraoperative potentials in terms of safety and predictive factors were investigated.Methods Each of the 76 myelopathic patients underwent surgical intervention. According to the wave configurations of the SEPs, the cases were categorised into four groups: Type Ⅰ, Ⅱ, Ⅲ and Ⅳ. The clinical myelopathy disability was classified and the severity of neurological deficits was scored. Clinical function after surgery was evaluated. Preoperative potentials and intraoperative monitoring were categorized. The correlations between evoked potentials detection, monitoring, myelopathy disability and surgical outcome in the different groups were discussed. Results According to the configurations of the SEPs, there were 27 patients (36%) of Type Ⅰ, 30 patients (39%) of Type Ⅱ, 8 patients (11%) of Type Ⅲ, and 11 patients (14%) of Type Ⅳ. The categorised evoked potentials were shown to be significantly associated with the clinical representation of myelopathy (P 〈0.01) and the recovery rate from identifiable SEPs waves (groups A, B and C) was significantly higher than unidentifiable waves (group D, P〈0.01). A deterioration of SEPs was detected in 23 cases (30%), whereas there was no change in 40 cases (53%) and improvements in 13 cases (17%). A significant difference in recovery rates could be observed in various monitoring groups within the short-term follow-up period, while there were no obvious differences in the long-term follow-up groups. Conclusions SEP technique is a valuable and practical tool for the diagnosis, monitoring and prognosis of myelopathy. Classified evoked potentials are well correlated with cervical spondyiotic myelopathy disability, and unidentifiable SEPs waves in patients are indicative of a relatively poor outcome. In addition, intraoperative monitoring of SEPs plays an

  20. Special Issue: The Potential Role for Community Monitoring in MRV and in Benefit Sharing in REDD+

    Directory of Open Access Journals (Sweden)

    Arturo Balderas Torres

    2015-01-01

    Full Text Available Since the early design of activities to reduce emissions from deforestation and forest degradation in developing countries (REDD+ under the United Nations Framework Convention on Climate Change (UNFCCC, the need to engage local communities and indigenous groups in monitoring and reporting has been recognized. REDD+ has advanced under the UNFCCC negotiations, but most countries still need to define formally what the role of communities in their national monitoring systems will be. Previous research and experiences have shown that local communities can effectively contribute in the monitoring of natural resources. This editorial introduces a Special Issue of Forests which discusses the implications of and potential for including community based monitoring (CBM in monitoring and benefit-sharing systems in REDD+. It outlines the main points of the nine contributions to the Special Issue which cover a wide geographical area and report on projects and research which engages more than 150 communities from eight different countries from Africa, Asia and Latin America. The editorial summarizes how the articles and reports build further understanding of the potential of CBM to contribute to the implementation, monitoring and distribution of benefits in REDD+. It also discusses the results of an on-going opinion survey on issues related to CBM and its relation to benefit sharing, which indicates that there is still disagreement on a number of key elements.

  1. Variations in retrieval monitoring during action memory judgments: evidence from event-related potentials (ERPs).

    Science.gov (United States)

    Leynes, P Andrew; Kakadia, Bhavika

    2013-02-01

    The present study investigated the neuroscience of memory for actions using event-related potentials (ERPs). Actions were performed, initiated but not completed (i.e., interrupted), or watched while the experimenter performed the action during encoding. Memory was assessed in a reality monitoring (RM) test (performed vs. watched actions), as well as in an internal source monitoring (ISM) test (performed vs. interrupted) while ERPs were recorded. Behavioral measures provided evidence of robust old/new recognition for all actions, but the analysis of source errors revealed that interrupted actions were often confused with performed actions. The ERP correlate of recollection, the parietal "old/new" effect (700-900ms), was observed for all actions. The right frontal "old/new" effect (1500-1800ms) that correlates with general memory monitoring was observed in RM but not in ISM. Instead, ISM was associated with the late posterior negativity (LPN) that has been connected to more specific memory monitoring. This pattern of ERP findings suggest that, in this context, general monitoring was used to discriminate self- versus other-performed actions, whereas more specific monitoring was required to support the discrimination of completed and interrupted actions. We argue that the mix of general/specific monitoring processes is shaped by the global retrieval context, which includes the number of memory features that overlap and the combination of sources being considered among other factors.

  2. Operational Use of the Air Quality Monitor on ISS and Potential for Air Quality Monitoring Onboard Submarines

    Science.gov (United States)

    Limero, Thomas; Jones, Jared; Wallace, William; Mudgett, Paul

    2015-01-01

    The air quality monitor (AQM) began operations on the International Space Station (ISS) in March 2013 and was validated for operational use in January 2014. The AQM is a gas chromatograph-differential mobility spectrometer that currently monitors 22 target compounds in the ISS atmosphere. Data are collected twice per week, although data collection can be more frequent in contingency situations. In its second year, the AQM has provided data to decision-makers on several ISS contaminant related issues in both air and water. AQM has been used in strictly air incidents, such as a potential ammonia leak, and to investigate air contaminants affecting the water processing (excess ethanol). In the latter case data from water monitors and AQM were compared to understand the issue with the water processor. Additionally, the AQM has been moved to different ISS modules to determine whether air is sufficiently mixed between modules so that a central LAB module location is representative of the entire ISS atmosphere. Historic data on the ISS atmosphere in different modules from archival samples (ground lab analysis) suggest that the atmosphere is usually homogenous. This presentation will briefly describe the technical aspects of the AQM operations and summarize the validation results. The main focus of the presentation will be to discuss the results from the AQM survey of the ISS modules and to show how the AQM data has contributed to an understanding of environmental issues that have arisen on ISS. Presentation of a potential ammonia leak (indicated by an alarm) in 2015 will illustrate the use and value of the AQM in such situations.

  3. Developmental changes in error monitoring : An event-related potential study

    NARCIS (Netherlands)

    Wiersema, Jan R.; van der Meere, Jacob J.; Roeyers, Herbert; Wiersema, R.J

    2007-01-01

    The aim of the study was to investigate the developmental trajectory of error monitoring. For this purpose, children (age 7-8), young adolescents (age 13-14) and adults (age 23-24) performed a Go/No-Go task and were compared on overt reaction time (RT) performance and on event-related potentials (ER

  4. [Intraoperative monitoring: visual evoked potentials in surgery of the sellar region].

    Science.gov (United States)

    Lorenz, M; Renella, R R

    1989-01-01

    During 18 sellar and perisellar operations the optic tract was monitored by visual evoked potentials (VEP). Deteriorations of the cortical responses were recorded in 73%. In this patients there was no close correlation between the intraoperative findings and the postoperative visual function. Only in those patients who showed no remarkable intraoperative changes VEP seemed to be of reliable prognostic value.

  5. Unscented Kalman filter assimilation of time-lapse self-potential data for monitoring solute transport

    Science.gov (United States)

    Cui, Yi-an; Liu, Lanbo; Zhu, Xiaoxiong

    2017-08-01

    Monitoring the extent and evolution of contaminant plumes in local and regional groundwater systems from existing landfills is critical in contamination control and remediation. The self-potential survey is an efficient and economical nondestructive geophysical technique that can be used to investigate underground contaminant plumes. Based on the unscented transform, we have built a Kalman filtering cycle to conduct time-lapse data assimilation for monitoring the transport of solute based on the solute transport experiment using a bench-scale physical model. The data assimilation was formed by modeling the evolution based on the random walk model and observation correcting based on the self-potential forward. Thus, monitoring self-potential data can be inverted by the data assimilation technique. As a result, we can reconstruct the dynamic process of the contaminant plume instead of using traditional frame-to-frame static inversion, which may cause inversion artifacts. The data assimilation inversion algorithm was evaluated through noise-added synthetic time-lapse self-potential data. The result of the numerical experiment shows validity, accuracy and tolerance to the noise of the dynamic inversion. To validate the proposed algorithm, we conducted a scaled-down sandbox self-potential observation experiment to generate time-lapse data that closely mimics the real-world contaminant monitoring setup. The results of physical experiments support the idea that the data assimilation method is a potentially useful approach for characterizing the transport of contamination plumes using the unscented Kalman filter (UKF) data assimilation technique applied to field time-lapse self-potential data.

  6. Potential for the Use of Wireless Sensor Networks for Monitoring of CO2 Leakage Risks

    Science.gov (United States)

    Pawar, R.; Illangasekare, T. H.; Han, Q.; Jayasumana, A.

    2015-12-01

    Storage of supercritical CO2 in deep saline geologic formation is under study as a means to mitigate potential global climate change from green house gas loading to the atmosphere. Leakage of CO2 from these formations poses risk to the storage permanence goal of 99% of injected CO2 remaining sequestered from the atmosphere,. Leaked CO2 that migrates into overlying groundwater aquifers may cause changes in groundwater quality that pose risks to environmental and human health. For these reasons, technologies for monitoring, measuring and accounting of injected CO2 are necessary for permitting of CO2 sequestration projects under EPA's class VI CO2 injection well regulations. While the probability of leakage related to CO2 injection is thought to be small at characterized and permitted sites, it is still very important to protect the groundwater resources and develop methods that can efficiently and accurately detect CO2 leakage. Methods that have been proposed for leakage detection include remote sensing, soil gas monitoring, geophysical techniques, pressure monitoring, vegetation stress and eddy covariance measurements. We have demonstrated the use of wireless sensor networks (WSN) for monitoring of subsurface contaminant plumes. The adaptability of this technology for leakage monitoring of CO2 through geochemical changes in the shallow subsurface is explored. For this technology to be viable, it is necessary to identify geochemical indicators such as pH or electrical conductivity that have high potential for significant change in groundwater in the event of CO2 leakage. This talk presents a conceptual approach to use WSNs for CO2 leakage monitoring. Based on our past work on the use of WSN for subsurface monitoring, some of the challenges that need to be over come for this technology to be viable for leakage detection will be discussed.

  7. Crack monitoring method based on Cu coating sensor and electrical potential technique for metal structure

    Directory of Open Access Journals (Sweden)

    Hou Bo

    2015-06-01

    Full Text Available Advanced crack monitoring technique is the cornerstone of aircraft structural health monitoring. To achieve real-time crack monitoring of aircraft metal structures in the course of service, a new crack monitoring method is proposed based on Cu coating sensor and electrical potential difference principle. Firstly, insulation treatment process was used to prepare a dielectric layer on structural substrate, such as an anodizing layer on 2A12-T4 aluminum alloy substrate, and then a Cu coating crack monitoring sensor was deposited on the structure fatigue critical parts by pulsed bias arc ion plating technology. Secondly, the damage consistency of the Cu coating sensor and 2A12-T4 aluminum alloy substrate was investigated by static tensile experiment and fatigue test. The results show that strain values of the coating sensor and the 2A12-T4 aluminum alloy substrate measured by strain gauges are highly coincident in static tensile experiment and the sensor has excellent fatigue damage consistency with the substrate. Thirdly, the fatigue performance discrepancy between samples with the coating sensor and original samples was investigated. The result shows that there is no obvious negative influence on the fatigue performance of the 2A12-T4 aluminum alloy after preparing the Cu coating sensor on its surface. Finally, crack monitoring experiment was carried out with the Cu coating sensor. The experimental results indicate that the sensor is sensitive to crack, and crack origination and propagation can be monitored effectively through analyzing the change of electrical potential values of the coating sensor.

  8. Investigating the potential use of environmental DNA (eDNA for genetic monitoring of marine mammals.

    Directory of Open Access Journals (Sweden)

    Andrew D Foote

    Full Text Available The exploitation of non-invasive samples has been widely used in genetic monitoring of terrestrial species. In aquatic ecosystems, non-invasive samples such as feces, shed hair or skin, are less accessible. However, the use of environmental DNA (eDNA has recently been shown to be an effective tool for genetic monitoring of species presence in freshwater ecosystems. Detecting species in the marine environment using eDNA potentially offers a greater challenge due to the greater dilution, amount of mixing and salinity compared with most freshwater ecosystems. To determine the potential use of eDNA for genetic monitoring we used specific primers that amplify short mitochondrial DNA sequences to detect the presence of a marine mammal, the harbor porpoise, Phocoena phocoena, in a controlled environment and in natural marine locations. The reliability of the genetic detections was investigated by comparing with detections of harbor porpoise echolocation clicks by static acoustic monitoring devices. While we were able to consistently genetically detect the target species under controlled conditions, the results from natural locations were less consistent and detection by eDNA was less successful than acoustic detections. However, at one site we detected long-finned pilot whale, Globicephala melas, a species rarely sighted in the Baltic. Therefore, with optimization aimed towards processing larger volumes of seawater this method has the potential to compliment current visual and acoustic methods of species detection of marine mammals.

  9. Sugammadex to reverse neuromuscular blockade and provide optimal conditions for motor-evoked potential monitoring

    Directory of Open Access Journals (Sweden)

    Mehdi Trifa

    2017-01-01

    Full Text Available Sugammadex is a novel pharmacologic agent, which reverses neuromuscular blockade (NMB via a mechanism that differs completely from acetylcholinesterase inhibitors. By encapsulating rocuronium, sugammadex can provide recovery of neuromuscular function even when there is a profound degree of NMB. We report anecdotal experience with the use of sugammadex to reverse NMB to facilitate intraoperative neurophysiological monitoring (motor evoked potentials in an adolescent with scoliosis during posterior spinal fusion. Its potential application in this unique clinical scenario is discussed, and potential dosing schemes are reviewed.

  10. Application of pulse contour cardiac output monitoring technique in hemodynamic monitoring in critical patients%脉搏轮廓心排血量监测技术在危重病患者血流动力学监测中的应用

    Institute of Scientific and Technical Information of China (English)

    房贺; 郑兴锋; 夏照帆

    2014-01-01

    Pulse contour cardiac output (PiCCO) monitoring is a new type of invasive hemodynamic monitoring technology,which is more and more often applied in perioperative period and the patients suffering from multiple injuries,septic shock,and extensive burn.With PiCCO one is able to monitor patients' hemodynamic indexes safely,timely,accurately,and continuously to provide reference for judgment of patients' condition and proper quality and quantity of fluid administration.This technique has a good prospect in clinical application.

  11. A Case Report of Intraoperative Monitoring During the Spinal Surgery by Means of Somatosensory Evoked Potentials

    Directory of Open Access Journals (Sweden)

    S.K. Shakoori

    2006-01-01

    Full Text Available Introduction : To prevent spinal lesions during surgery we can use somatosensory evoked potentials (SSEP to monitor the patients who are under surgery particularly the ones under the spinal cord surgery. Case Report: The following case refers to the monitoring of a 23 year – old youth with the use of Intraoperative SSEP who has been under the operation of tumor removal with the diagnosis of space occupying mass in the conous region of spine in Tabriz Shohada Hospital. Conclusion: SSEP study for left tibial nerve after surgery was the same as before surgery. Pathology diagnosis was epandymom. Patient gave recovery process in few days.

  12. Clinical utility and limitations of intraoperative monitoring of visual evoked potentials.

    Directory of Open Access Journals (Sweden)

    Yeda Luo

    Full Text Available During surgeries that put the visual pathway at risk of injury, continuous monitoring of the visual function is desirable. However, the intraoperative monitoring of the visual evoked potential (VEP is not yet widely used. We evaluate here the clinical utility of intraoperative VEP monitoring.We analyzed retrospectively 46 consecutive surgeries in 2011-2013. High luminance stimulating devices delivered flash stimuli on the closed eyelid during intravenous anesthesia. We monitored VEP features N75 and P100 and took patients' preoperative and postoperative visual function from patient charts. Postoperative ophthalmologic workup was performed in 25 (54% patients and preoperatively in 28 (61% patients.VEP recordings were feasible in 62 of 85 eyes (73% in 46 patients. All 23 eyes without VEP had impaired vision. During surgery, VEPs remained stable throughout surgery in 50 eyes. In 44 of these, visual function did not deteriorate and three patients (6 eyes developed hemianopia. VEP decreased transiently in 10 eyes and visual function of all was preserved. VEPs were lost permanently in 2 eyes in two patients without new postoperative visual impairment.Satisfactory intraoperative VEP monitoring was feasible in all patients except in those with severe visual impairment. Preservation of VEPs predicted preserved visual function. During resection of lesions in the visual cortex, VEP monitoring could not detect new major visual field defects due to injury in the posterior visual pathway. Intraoperative VEPs were sensitive enough to detect vascular damage during aneurysm clipping and mechanical manipulation of the anterior visual pathway in an early reversible stage. Intraoperative VEP monitoring influenced surgical decisions in selected patients and proved to be a useful supplement to the toolbox of intraoperative neurophysiological monitoring.

  13. Ground-coupled airwaves at Pavlof Volcano, Alaska, and their potential for eruption monitoring

    Science.gov (United States)

    Smith, Cassandra M.; McNutt, Stephen R.; Thompson, Glenn

    2016-07-01

    An abnormally high number of explosion quakes were noted during the monitoring effort for the 2007 eruption of Pavlof Volcano on the Alaska Peninsula. In this study, we manually cataloged the explosion quakes from their characteristic ground-coupled airwaves. This study investigates how the ground-coupled airwaves might be used in a monitoring or analysis effort by estimating energy release and gas mass release. Over 3 × 104 quakes were recorded. The energy release from the explosions is approximated to be 3 × 1011 J, and the total gas mass (assuming 100 % water) released was 450 t. The tracking of explosion quakes has the potential to estimate relative eruption intensity as a function of time and is thus a useful component of a seismic monitoring program.

  14. Recent Trends in Rapid Environmental Monitoring of Pathogens and Toxicants: Potential of Nanoparticle-Based Biosensor and Applications

    Directory of Open Access Journals (Sweden)

    Preeyaporn Koedrith

    2015-01-01

    Full Text Available Of global concern, environmental pollution adversely affects human health and socioeconomic development. The presence of environmental contaminants, especially bacterial, viral, and parasitic pathogens and their toxins as well as chemical substances, poses serious public health concerns. Nanoparticle-based biosensors are considered as potential tools for rapid, specific, and highly sensitive detection of the analyte of interest (both biotic and abiotic contaminants. In particular, there are several limitations of conventional detection methods for water-borne pathogens due to low concentrations and interference with various enzymatic inhibitors in the environmental samples. The increase of cells to detection levels requires long incubation time. This review describes current state of biosensor nanotechnology, the advantage over conventional detection methods, and the challenges due to testing of environmental samples. The major approach is to use nanoparticles as signal reporter to increase output rather than spending time to increase cell concentrations. Trends in future development of novel detection devices and their advantages over other environmental monitoring methodologies are also discussed.

  15. Direct motor evoked potentials and cortical mapping using the NIM® nerve monitoring system: A technical note.

    Science.gov (United States)

    Bharadwaj, Suparna; Haji, Faizal; Hebb, Matthew; Chui, Jason

    2017-04-01

    Motor evoked potentials (MEPs) are commonly used to prevent neurological injury when operating in close proximity to the motor cortex or corticospinal pathway. We report a novel application of the NIM® nerve monitoring system (Medtronic@ NIM response 3.0) for intraoperative direct cortical (dc)-MEPs monitoring. A 69-year-old female patient presented with a 4month history of progressive left hemiparesis resulting from a large right sided posterior frontal meningioma that abutted and compressed the motor cortex. Motor cortical mapping and MEPs were indicated. The patient was anesthetized and maintained on total intravenous anesthetics. Compound muscle action potentials (CMAP) of the right upper limb were monitored using the NIM system. After a craniotomy was performed, we first used the Ojemann stimulator (monopolar) for dc-stimulation and then switched to use the monopolar nerve stimulator probe of the NIM system. The CMAP response was successfully elicited using the NIM stimulating probe (pulse width=250s, train frequency=7pulses/s, current=20mA). A gross total resection of the tumor was achieved with intermittent cortical mapping of MEPs. There were no intraoperative complications and the patient's motor function was preserved after the surgery. In this case, we reported the successful use of the NIM nerve monitoring system to elicit dc-MEPs under general anesthesia. The advantages of using this system include a simple set up and application, neurosurgeon familiarity, wide availability and lower cost. dc-MEPs can be achieved using the NIM system. We conclude that the NIM nerve monitoring system is a feasible alternative to standard neurophysiological monitoring systems. Copyright © 2016 Elsevier Ltd. All rights reserved.

  16. Immobilization and surface functionalization of gold nanoparticles monitored via streaming current/potential measurements.

    Science.gov (United States)

    Greben, Kyrylo; Li, Pinggui; Mayer, Dirk; Offenhäusser, Andreas; Wördenweber, Roger

    2015-05-14

    A streaming current/potential method is optimized and used for the analysis of the variation of the surface potential upon chemical modifications of a complex interface consisting of different organic molecules and gold nanoparticles (AuNPs). The surfaces of Si/SiO2 substrates modified with 3-aminopropyltriethoxysilane (APTES), AuNPs, and 11-amino-1-undecanethiol (aminothiols) are analyzed via pH and time dependent ζ potential measurements that reveal the stability and modification of the surface and identify crucial parameters for each individual preparation step. For instance, surface activation and especially molecular adsorbate layers tend not to be stable in time, whereas the substrate and the AuNPs provide a stable surface potential as long as impurities are avoided. It is shown that the streaming potential/current technique represents an ideal tool to analyze and monitor the complex surfaces and their modification.

  17. Comparative evaluation of potential indicators and temporal sampling protocols for monitoring genetic erosion.

    Science.gov (United States)

    Hoban, Sean; Arntzen, Jan A; Bruford, Michael W; Godoy, José A; Rus Hoelzel, A; Segelbacher, Gernot; Vilà, Carles; Bertorelle, Giorgio

    2014-11-01

    Genetic biodiversity contributes to individual fitness, species' evolutionary potential, and ecosystem stability. Temporal monitoring of the genetic status and trends of wild populations' genetic diversity can provide vital data to inform policy decisions and management actions. However, there is a lack of knowledge regarding which genetic metrics, temporal sampling protocols, and genetic markers are sufficiently sensitive and robust, on conservation-relevant timescales. Here, we tested six genetic metrics and various sampling protocols (number and arrangement of temporal samples) for monitoring genetic erosion following demographic decline. To do so, we utilized individual-based simulations featuring an array of different initial population sizes, types and severity of demographic decline, and DNA markers [single nucleotide polymorphisms (SNPs) and microsatellites] as well as decline followed by recovery. Number of alleles markedly outperformed other indicators across all situations. The type and severity of demographic decline strongly affected power, while the number and arrangement of temporal samples had small effect. Sampling 50 individuals at as few as two time points with 20 microsatellites performed well (good power), and could detect genetic erosion while 80-90% of diversity remained. This sampling and genotyping effort should often be affordable. Power increased substantially with more samples or markers, and we observe that power of 2500 SNPs was nearly equivalent to 250 microsatellites, a result of theoretical and practical interest. Our results suggest high potential for using historic collections in monitoring programs, and demonstrate the need to monitor genetic as well as other levels of biodiversity.

  18. Detection of microbial contaminations in drinking water using ATP measurements – evaluating potential for online monitoring

    DEFF Research Database (Denmark)

    Vang, Óluva Karin; Corfitzen, Charlotte B.; Albrechtsen, Hans-Jørgen

    2011-01-01

    There is an increasing call for fast and reliable methods for continuous monitoring of microbial drinking water quality in order to protect public health. The potential for Adenosine triphosphate (ATP) measurements as a real-time analysis for continuous monitoring of microbial drinking water...... quality was investigated through simulation of two contamination scenarios, i.e. drinking water contaminated with waste water and surface water at various concentrations. With ATP measurements it was possible to detect waste water diluted 1000-10,000 times in drinking water depending on sensitivity...... of reagent kit. Surface water diluted 100-1000 times was detected in drinking water with ATP measurements. ATP has the potential as an early warning tool, especially in the period when the contamination concentration is high. 2011 © American Water Works Association AWWA WQTC Conference Proceedings All Rights...

  19. Detection of microbial contaminations in drinking water using ATP measurements – evaluating potential for online monitoring

    DEFF Research Database (Denmark)

    Vang, Óluva Karin; Corfitzen, Charlotte B.; Albrechtsen, Hans-Jørgen

    2011-01-01

    There is an increasing call for fast and reliable methods for continuous monitoring of microbial drinking water quality in order to protect public health. The potential for Adenosine triphosphate (ATP) measurements as a real-time analysis for continuous monitoring of microbial drinking water...... quality was investigated through simulation of two contamination scenarios, i.e. drinking water contaminated with waste water and surface water at various concentrations. With ATP measurements it was possible to detect waste water diluted 1000-10,000 times in drinking water depending on sensitivity...... of reagent kit. Surface water diluted 100-1000 times was detected in drinking water with ATP measurements. ATP has the potential as an early warning tool, especially in the period when the contamination concentration is high. 2011 © American Water Works Association AWWA WQTC Conference Proceedings All Rights...

  20. Surveillance methods for identifying, characterizing, and monitoring tobacco products: potential reduced exposure products as an example

    Science.gov (United States)

    O’Connor, Richard J.; Cummings, K. Michael; Rees, Vaughan W.; Connolly, Gregory N.; Norton, Kaila J.; Sweanor, David; Parascandola, Mark; Hatsukami, Dorothy K.; Shields, Peter G.

    2015-01-01

    Tobacco products are widely sold and marketed, yet integrated data systems for identifying, tracking, and characterizing products are lacking. Tobacco manufacturers recently have developed potential reduction exposure products (PREPs) with implied or explicit health claims. Currently, a systematic approach for identifying, defining, and evaluating PREPs sold at the local, state or national levels in the US has not been developed. Identifying, characterizing, and monitoring new tobacco products could be greatly enhanced with a responsive surveillance system. This paper critically reviews available surveillance data sources for identifying and tracking tobacco products, including PREPs, evaluating strengths and weaknesses of potential data sources in light of their reliability and validity. Absent regulations mandating disclosure of product-specific information, it is likely that public health officials will need to rely on a variety of imperfect data sources to help identify, characterize, and monitor tobacco products, including PREPs. PMID:19959680

  1. Performance monitoring is altered in adult ADHD: a familial event-related potential investigation

    OpenAIRE

    McLoughlin, G; Albrecht, B.; Banaschewski, T.; Rothenberger, A.; Brandeis, D; Asherson, P.; Kuntsi, J.

    2009-01-01

    BACKGROUND: Attention deficit hyperactivity disorder (ADHD) is a common neurodevelopmental disorder that starts in childhood and frequently persists in adults. Electrophysiological studies in children with ADHD provide evidence for abnormal performance monitoring processes and familial association of these processes with ADHD. It is not yet known whether these processes show the same abnormalities and familial effects in adults. METHOD: We investigated event-related potential (ERP) indices of...

  2. Data Acquisition System for In Situ Monitoring of Chemoelectrical Potential in Living Plant Fuel Cells

    Science.gov (United States)

    Choo, Ying Ying

    2016-01-01

    Photosynthesis process in plants generates numerous sources of bioenergy. However, only a small fraction is readily exploited for electrical energy. The impact of environmental factors is one of the significant physiological influences on the electrical potential of the plants. Hence, we developed a data acquisition (DAQ) system for instantaneous monitoring of electrical potential in plants and Aloe vera was used as a plant sample. The static response characterization, capability index (P/T), and Pearson's coefficient of correlation procedures were applied to assess the reliability of the obtained data. This developed system offers the capability of in situ monitoring and detecting gradual changes in the electrical potential of plants up to a correlational strength of greater than 0.7. Interpretation of the electrical signal mechanisms in the Aloe vera plant and the optimization of the electricity can be achieved through the application of this monitoring system. This system, therefore, can serve as a tool to measure and analyze the electrical signals in plants at different conditions. PMID:27660638

  3. Data Acquisition System for In Situ Monitoring of Chemoelectrical Potential in Living Plant Fuel Cells

    Directory of Open Access Journals (Sweden)

    Fuei Pien Chee

    2016-01-01

    Full Text Available Photosynthesis process in plants generates numerous sources of bioenergy. However, only a small fraction is readily exploited for electrical energy. The impact of environmental factors is one of the significant physiological influences on the electrical potential of the plants. Hence, we developed a data acquisition (DAQ system for instantaneous monitoring of electrical potential in plants and Aloe vera was used as a plant sample. The static response characterization, capability index (P/T, and Pearson’s coefficient of correlation procedures were applied to assess the reliability of the obtained data. This developed system offers the capability of in situ monitoring and detecting gradual changes in the electrical potential of plants up to a correlational strength of greater than 0.7. Interpretation of the electrical signal mechanisms in the Aloe vera plant and the optimization of the electricity can be achieved through the application of this monitoring system. This system, therefore, can serve as a tool to measure and analyze the electrical signals in plants at different conditions.

  4. Monitoring genetic and metabolic potential for in situ bioremediation: Mass spectrometry. 1997 annual progress report

    Energy Technology Data Exchange (ETDEWEB)

    Buchanan, M.V.; Hurst, G.B.; Britt, P.F.; McLuckey, S.A.; Doktycz, M.J.

    1997-09-01

    'A number of US Department of Energy (DOE) sites are contaminated with mixtures of dense non-aqueous phase liquids (DNAPLs) such as carbon tetrachloride, chloroform,. perchloroethylene, and trichloroethylene. At many of these sites, in situ microbial bioremediation is an attractive strategy for cleanup because it has the potential to degrade DNAPLs in situ without producing toxic byproducts. A rapid screening method to determine the broad range metabolic and genetic potential for contaminant degradation would greatly reduce the cost and time involved in assessment for in situ bioremediation as well as for monitoring ongoing bioremediation treatment. In this project, the ORNL Organic Mass Spectrometry (OMS) group is developing mass-spectrometry-based methods to screen for the genetic and metabolic potential for assessment and monitoring of in situ bioremediation of DNAPLs. In close collaboration, Professor Mary Lidstrom''s group at the University of Washington is identifying short DNA sequences related to microbial processes involved in the biodegradation of pollutants. This work will lay the foundation for development of a field-portable mass-spectrometry-based technique for rapid assessment and monitoring of bioremediation processes on site.'

  5. Monitoring somatosensory evoked potentials in spinal cord ischemia-reperfusion injury

    Institute of Scientific and Technical Information of China (English)

    Yiming Ji; Bin Meng; Chenxi Yuan; Huilin Yang; Jun Zou

    2013-01-01

    It remains unclear whether spinal cord ischemia-reperfusion injury caused by ischemia and other non-mechanical factors can be monitored by somatosensory evoked potentials. Therefore, we monitored spinal cord ischemia-reperfusion injury in rabbits using somatosensory evoked potential detection technology. The results showed that the somatosensory evoked potential latency was significantly prolonged and the amplitude significantly reduced until it disappeared during the period of spinal cord ischemia. After reperfusion for 30-180 minutes, the amplitude and latency began to gradual y recover; at 360 minutes of reperfusion, the latency showed no significant difference compared with the pre-ischemic value, while the somatosensory evoked potential amplitude in-creased, and severe hindlimb motor dysfunctions were detected. Experimental findings suggest that changes in somatosensory evoked potential latency can reflect the degree of spinal cord ischemic injury, while the amplitude variations are indicators of the late spinal cord reperfusion injury, which provide evidence for the assessment of limb motor function and avoid iatrogenic spinal cord injury.

  6. A novel electrical potential sensing method for in vitro stent fracture monitoring and detection.

    Science.gov (United States)

    Park, Chan-Hee; Tijing, Leonard D; Yun, Yeoheung; Kim, Cheol Sang

    2011-01-01

    This article describes a preliminary investigation and prototype fabrication of a novel potential sensing method to continuously monitor vascular stent fractures. A potential measurement system consisting of Wheatstone bridge circuit and signal conditioning circuit was designed for the cardiovascular stent durability and fatigue test. Each end of a bare and polyurethane-covered Nitinol vascular stent was electrically connected to the potential measurement system and then immersed either in simulated body fluid (SBF) media or distilled water at 36.4 ± 1 °C. When the stent experienced fracture (i.e., a cut), its electrical potential decreased with an increase in electrical resistance. This method successfully measured fractures in the stent regardless of location. Furthermore, the number of cycles at the onset of stent fracture was accurately detected and continuously monitored using this technique. Thus, the present fracture detection method, which to our knowledge is the first ever report to use electrical potential measurement for stent durability test, gives a fast, real-time, accurate and efficient detection of fractures in stent during in vitro fatigue and durability test.

  7. Ketamine-Based Anesthetic Protocols and Evoked Potential Monitoring: A Risk/Benefit Overview

    Science.gov (United States)

    Stoicea, Nicoleta; Versteeg, Gregory; Florescu, Diana; Joseph, Nicholas; Fiorda-Diaz, Juan; Navarrete, Víctor; Bergese, Sergio D.

    2016-01-01

    Since its discovery, ketamine, a non-competitive N-methyl D-aspartate (NMDA) receptor antagonist related to phencyclidine, has been linked to multiple adverse reactions sometimes described as “out of body” and “near death experiences,” including emergence phenomena, delusions, hallucinations, delirium, and confusion. Due to these effects, ketamine has been withdrawn from mainstream anesthetic use in adult patients. Evoked potentials (EPs) are utilized to monitor neural pathways during surgery, detect intraoperative stress or damage, detect and define the level of neural lesions, and define abnormalities. Unfortunately, many of the volatile anesthetics commonly used during spinal and neurologic procedures suppress EP amplitude and monitoring. Ketamine has been found in several preclinical and clinical studies to actually increase EP amplitude and thus has been used as an analgesic adjunct in procedures where EP monitoring is critical. Once the gap in our knowledge of ketamine's risks has been sufficiently addressed in animal models, informed clinical trials should be conducted in order to properly incorporate ketamine-based anesthetic regimens during EP-monitored neurosurgeries. PMID:26909017

  8. THE APPLICATION OF CORTICAL SOMATOSENSORY EVOKED POTENTIAL MONITORING IN CHILD SCOLIOSIS SURGERY

    Institute of Scientific and Technical Information of China (English)

    白斌; 王坤正; 同志勤; 刘文科; 宋金辉; 袁国莲

    2003-01-01

    Objective To study the application value of cortical somatosensory evoked potential (CSEP) monitoring in child scoliosis surgery. Methods In surgeries of fifty-one children with scoliosis, the CSEP changes were continuously recorded by evoked potential instrument. The operations were performed under the guidance of CSEP monitoring. Results Before propping and reshaping, the latencies and amplitudes in all cases had no change. During propping and reshaping, the latencies of all cases were slowly elongated, but all less than 10 percent. The amplitudes in 15 cases dropped to 55 percent, but returned to 80 percent 3-8 minutes after stopping the operations or partially loosening the propped rods at once. The amplitude in one case suddenly dropped to 37 percent and returned to 54 percent half an hour after loosening the propped rods at once and recovered to the normal range one day after operation. All cases got ideal orthopedic results and no one had neurological complications post operation. Conclusion CSEP can accurately monitor the spinal injury and has a great value in preventing the spinal injury in child scoliosis surgery.

  9. On the potential application of land surface models for drought monitoring in China

    Science.gov (United States)

    Zhang, Liang; Zhang, Huqiang; Zhang, Qiang; Li, Yaohui; Zhao, Jianhua

    2017-05-01

    The potential of using land surface models (LSMs) to monitor near-real-time drought has not been fully assessed in China yet. In this study, we analyze the performance of such a system with a land surface model (LSM) named the Australian Community Atmosphere Biosphere Land Exchange model (CABLE). The meteorological forcing datasets based on reanalysis products and corrected by observational data have been extended to near-real time for semi-operational trial. CABLE-simulated soil moisture (SM) anomalies are used to characterize drought spatial and temporal evolutions. One outstanding feature in our analysis is that with the same meteorological data, we have calculated a range of drought indices including Standardized Precipitation Index (SPI), Standardized Precipitation-Evapotranspiration Index (SPEI), Palmer Drought Severity Index (PDSI). We have assessed the similarity among these indices against observed SM over a number of regions in China. While precipitation is the dominant factor in the drought development, relationships between precipitation, evaporation, and soil moisture anomalies vary significantly under different climate regimes, resulting in different characteristics of droughts in China. The LSM-based trial system is further evaluated for the 1997/1998 drought in northern China and 2009/2010 drought in southwestern China. The system can capture the severities and temporal and spatial evolutions of these drought events well. The advantage of using a LSM-based drought monitoring system is further demonstrated by its potential to monitor other consequences of drought impacts in a more physically consistent manner.

  10. On the potential application of land surface models for drought monitoring in China

    Science.gov (United States)

    Zhang, Liang; Zhang, Huqiang; Zhang, Qiang; Li, Yaohui; Zhao, Jianhua

    2016-01-01

    The potential of using land surface models (LSMs) to monitor near-real-time drought has not been fully assessed in China yet. In this study, we analyze the performance of such a system with a land surface model (LSM) named the Australian Community Atmosphere Biosphere Land Exchange model (CABLE). The meteorological forcing datasets based on reanalysis products and corrected by observational data have been extended to near-real time for semi-operational trial. CABLE-simulated soil moisture (SM) anomalies are used to characterize drought spatial and temporal evolutions. One outstanding feature in our analysis is that with the same meteorological data, we have calculated a range of drought indices including Standardized Precipitation Index (SPI), Standardized Precipitation-Evapotranspiration Index (SPEI), Palmer Drought Severity Index (PDSI). We have assessed the similarity among these indices against observed SM over a number of regions in China. While precipitation is the dominant factor in the drought development, relationships between precipitation, evaporation, and soil moisture anomalies vary significantly under different climate regimes, resulting in different characteristics of droughts in China. The LSM-based trial system is further evaluated for the 1997/1998 drought in northern China and 2009/2010 drought in southwestern China. The system can capture the severities and temporal and spatial evolutions of these drought events well. The advantage of using a LSM-based drought monitoring system is further demonstrated by its potential to monitor other consequences of drought impacts in a more physically consistent manner.

  11. Conceptual design of a high precision dual directional beam position monitoring system for beam crosstalk cancellation and improved output pulse shapes

    Energy Technology Data Exchange (ETDEWEB)

    Thieberger P.; Dawson, C.; Fischer, W.; Gassner, D.; Hulsart, R.; Mernick, K.; Michnoff, R.; Minty, M.

    2012-04-15

    The Relativistic Heavy Ions Collider (RHIC) would benefit from improved beam position measurements near the interaction points that see both beams, especially as the tolerances become tighter when reducing the beam sizes to obtain increased luminosity. Two limitations of the present beam position monitors (BPMs) would be mitigated if the proposed approach is successful. The small but unavoidable cross-talk between signals from bunches traveling in opposite directions when using conventional BPMs will be reduced by adopting directional BPMs. Further improvements will be achieved by cancelling residual cross-talk using pairs of such BPMs. Appropriately delayed addition and integration of the signals will also provide pulses with relatively flat maxima that will be easier to digitize by relaxing the presently very stringent timing requirements.

  12. Identification and description of potential ground-water quality monitoring wells in Florida

    Science.gov (United States)

    Seaber, P.R.; Thagard, M.E.

    1986-01-01

    The results of a survey of existing wells in Florida that meet the following criteria are presented: (1) well location is known , (2) principal aquifer is known, (3) depth of well is known, (4) well casing depth is known, (5) well water had been analyzed between 1970 and 1982, and (6) well data are stored in the U.S. Geological Survey 's (USGS) computer files. Information for more than 20,000 wells in Florida were stored in the USGS Master Water Data Index of the National Water Data Exchange and in the National Water Data Storage and Retrieval System 's Groundwater Site Inventory computerized files in 1982. Wells in these computer files that had been sampled for groundwater quality before November 1982 in Florida number 13,739; 1,846 of these wells met the above criteria and are the potential (or candidate) groundwater quality monitoring wells included in this report. The distribution by principal aquifer of the 1,846 wells identified as potential groundwater quality monitoring wells is as follows: 1,022 tap the Floridan aquifer system, 114 tap the intermediate aquifers, 232 tap the surficial aquifers, 246 tap the Biscayne aquifer, and 232 tap the sand-and-gravel aquifer. These wells are located in 59 of Florida 's 67 counties. This report presents the station descriptions, which include location , site characteristics, period of record, and the type and frequency of chemical water quality data collected for each well. The 1,846 well locations are plotted on 14 USGS 1:250,000 scale, 1 degree by 2 degree, quadrangle maps. This relatively large number of potential (or candidate) monitoring wells, geographically and geohydrologically dispersed, provides a basis for a future groundwater quality monitoring network and computerized data base for Florida. There is a large variety of water quality determinations available from these wells, both areally and temporally. Future sampling of these wells would permit analyses of time and areal trends for selected water quality

  13. The sea surface currents as a potential factor in the estimation and monitoring of wave energy potential

    Science.gov (United States)

    Zodiatis, George; Galanis, George; Nikolaidis, Andreas; Stylianoy, Stavros; Liakatas, Aristotelis

    2015-04-01

    The use of wave energy as an alternative renewable is receiving attention the last years under the shadow of the economic crisis in Europe and in the light of the promising corresponding potential especially for countries with extended coastline. Monitoring and studying the corresponding resources is further supported by a number of critical advantages of wave energy compared to other renewable forms, like the reduced variability and the easier adaptation to the general grid, especially when is jointly approached with wind power. Within the framework, a number of countries worldwide have launched research and development projects and a significant number of corresponding studies have been presented the last decades. However, in most of them the impact of wave-sea surface currents interaction on the wave energy potential has not been taken into account neglecting in this way a factor of potential importance. The present work aims at filling this gap for a sea area with increased scientific and economic interest, the Eastern Mediterranean Sea. Based on a combination of high resolution numerical modeling approach with advanced statistical tools, a detailed analysis is proposed for the quantification of the impact of sea surface currents, which produced from downscaling the MyOcean-FO regional data, to wave energy potential. The results although spatially sensitive, as expected, prove beyond any doubt that the wave- sea surface currents interaction should be taken into account for similar resource analysis and site selection approaches since the percentage of impact to the available wave power may reach or even exceed 20% at selected areas.

  14. Beyond measures and monitoring: Realizing the potential of feedback-informed treatment.

    Science.gov (United States)

    Miller, Scott D; Hubble, Mark A; Chow, Daryl; Seidel, Jason

    2015-12-01

    More than a dozen randomized controlled trials and several meta-analyses have provided strong empirical support for routine outcome monitoring (ROM) in clinical practice. Despite current enthusiasm, advances in implementation, and the growing belief among some proponents and policymakers that ROM represents a major revolution in the practice of psychotherapy, other research has suggested that the focus on measurement and monitoring is in danger of missing the point. Any clinical tool or technology is only as good as the therapist who uses it. Failing to attend to the therapist's contribution, the long neglected variable in psychotherapy outcome, ensures that efforts to create, research, and refine new outcome measurement systems will inevitably fall short. Research from the field of expertise and expert performance provides guidance for realizing the full potential of ROM.

  15. Value of visual evoked potential monitoring during trans-sphenoidal pituitary surgery.

    Science.gov (United States)

    Chacko, A G; Babu, K S; Chandy, M J

    1996-06-01

    The visual outcome of 22 patients undergoing trans-sphenoidal excision of pituitary macroadenomas with intraoperative flash visual evoked potential (VEP) monitoring (Group A), was compared with a non-randomized group of 14 patients who had undergone similar operations without VEP monitoring (Group B). Tumour size, preoperative visual acuity, peripheral fields, and latencies and amplitudes of P1 and P2 were analysed to ascertain the best predictor of postoperative visual function. It was found that patients in Group A had a significantly greater improvement in field defects than those in Group B. There was no difference in postoperative improvement in visual acuity between the two groups. None of the variables analysed were good predictors of visual outcome.

  16. Present and potential nitrogen outputs from Norwegian soft water lakes – an assessment made by applying the steady-state First-order Acidity Balance (FAB model

    Directory of Open Access Journals (Sweden)

    Ø. Kaste

    2002-01-01

    Full Text Available The steady-state First-order Acidity Balance (FAB model for calculating critical loads of sulphur (S and nitrogen (N is applied to 609 Norwegian soft-water lakes to assess the future nitrate (NO3‾ leaching potential under present (1992-96 S and N deposition. The lakes were separated into five groups receiving increasing levels of N deposition (-2yr-1. Using long-term sustainable N sink rates presently recommended for FAB model applications, N immobilisation, net N uptake in forests, denitrification and in-lake N retention were estimated for each group of lakes. Altogether, the long-term N sinks constituted 9.9 ± 3.2 to 40.5 ± 11.4 meq m-2yr-1 in the lowest and highest N deposition categories, respectively. At most sites, the current N deposition exceeds the amount of N retained by long-term sustainable N sinks plus the NO3‾ loss via the lake outlets. This excess N, which is currently retained within the catchments may, according to the FAB model, leach as acidifying NO3‾ in the future. If these predictions are fulfilled, NO3‾ leaching at sites in the various N deposition categories will increase dramatically from present (1995 mean levels of 1-20 meq m-2yr-1, to mean levels of 7-70 meq m-2yr-1 at future steady state. To illustrate the significance of such an increase in NO3‾ leaching, the mean Acid Neutralising Capacity (ANC at sites in the highest N deposition category may decrease from -18 ± 15 μeq L-1 at present, to -40 ± 20 μeq L-1. Under present S and N deposition levels, the FAB model predicts that 46% of the Norwegian lakes may experience exceedances of critical loads for acidifying deposition. In comparison, the Steady-State Water Chemistry model (SSWC, which considers only the present N leaching level, estimates critical load exceedances in 37% of the lakes under the same deposition level. Thus far, there are great uncertainties regarding both the time scales and the extent of future N leaching, and it is largely unknown

  17. Fourier transformed steady-state flash evoked potentials for continuous monitoring of visual pathway function.

    Science.gov (United States)

    Bergholz, R; Lehmann, T N; Fritz, G; Rüther, K

    2008-05-01

    Monitoring of somatosensory, motor and auditory pathway function by evoked potentials is routine in surgery placing these pathways at risk. However, visual pathway function remains yet inaccessible to a reliable monitoring. For this study, a method of continuous recordings was developed and tested. Steady-state visual evoked potentials were elicited by flash stimulation at 16 Hz and analysed using discrete Fourier transform. Amplitude and phase of the fundamental response were dynamically averaged and continuously plotted in a trend graph. The method was applied on awake individuals with normal vision and on patients undergoing neurosurgery. In most individuals it was possible to continuously record significant responses. Surprisingly, characteristic time-courses of amplitude and phase were observed in several subjects. These findings were attributed mainly to flicker-adaptation. During anesthesia, amplitude and signal-to-noise ratio were markedly smaller. Signal recognition was facilitated when potentials were recorded with a subdural electrode placed directly at the occipital pole. The anesthetic agent propofol had a major impact on the recordings.

  18. Monitoring Potential Transport of Radioactive Contaminants in Shallow Ephemeral Channels: FY2013 and FY2014 (revised)

    Energy Technology Data Exchange (ETDEWEB)

    Mizell, Steve A. [Desert Research Inst. (DRI), Las Vegas, NV (United States); Miller, Julianne J. [Desert Research Inst. (DRI), Las Vegas, NV (United States); McCurdy, Greg D. [Desert Research Inst. (DRI), Reno, NV (United States); Campbell, Scott A. [Desert Research Inst. (DRI), Las Vegas, NV (United States)

    2017-06-01

    The Desert Research Institute (DRI) is conducting a field assessment of the potential for contaminated soil to be transported from the Smoky Contamination Area (CA) as a result of storm runoff, which supports National Nuclear Security Administration (NNSA) efforts to complete regulatory closure of the Soils Corrective Action Unit (CAU) contamination areas. The work is intended to confirm the likely mechanism of transport and determine the meteorological conditions that might cause movement of contaminated soils, as well as determine the particle size fraction that is most closely associated with transported radionuclide-contaminated soils. These data will facilitate the appropriate closure design and post-closure monitoring program.

  19. The potential of cellular network infrastructures for sudden rainfall monitoring in dry climate regions

    Science.gov (United States)

    David, N.; Alpert, P.; Messer, H.

    2013-09-01

    Monitoring of precipitation and in particular sudden rain, in rural dry climate regions, is a subject of great significance in several weather related processes such as soil erosion, flash flooding, triggering epidemics and more. The rainfall monitoring facilities in these regions and as a result precipitation data are, however, commonly, severely lacking. As was recently shown, cellular networks infrastructures supply high resolution precipitation measurements at ground level while often being situated in dry areas, covering large parts of these climatic zones. The potential found in these systems to provide early monitoring and essential precipitation information, directly from arid regions, based on standard measurements of commercial microwave links, is exemplified here over the Negev and the Southern Judean desert, South Israel. We present the results of two different rainfall events occurred in these regions. It is shown that the microwave system measured precipitation between at least 50 min (in case 1) and at least 1 h and 40 min (in case 2) before each of the sparse rain gauges. During each case, the radar system, located relatively far from the arid sites, provided measurements from heights of at least 1500 m and 2000 m above surface, respectively. A third case study demonstrates a relative advantage of microwave links to measure precipitation intensity with respect to the radar system, over an area of complex topography located in northeastern Israel, which is relatively far (~ 150 km) from the radar.

  20. Visual evoked potentials for intraoperative neurophysiologic monitoring using total intravenous anesthesia.

    Science.gov (United States)

    Wiedemayer, Helmut; Fauser, Barbara; Armbruster, W; Gasser, Thomas; Stolke, Dietmar

    2003-01-01

    Conflicting reports on the usefulness of intraoperative monitoring of visual function by means of visual evoked potentials (VEPs) initiated this study. In 32 patients without visual problems, VEPs were recorded to evaluate the reliability for intraoperative monitoring with total intravenous anesthesia. All patients underwent noncranial surgery. Using a standard technique, VEPs were recorded preoperatively in the awake patients and after induction of anesthesia during surgery. A total of 1436 intraoperative traces were recorded and analyzed. A minor prolongation of the P100 latency of 8% and a more pronounced attenuation of the P100-N145 amplitude of 60% were observed in the anesthetized patients. In most of the anesthetized patients, a stable recording of VEPs was not obtainable. In 4 patients (12.5%), clearly identifiable VEP peaks were detected in more than 90% of the traces recorded intraoperatively. In 88% of the patients, reproducible VEPs were obtained in less than 75% of the intraoperative traces only. We concluded that with standard recording techniques and total intravenous anesthesia, intraoperative VEP monitoring in surgically anesthetized patients is not reliable.

  1. Monitoring underground migration of sequestered CO2 using self-potential methods

    Science.gov (United States)

    Ishido, T.; Pritchett, J.; Tosha, T.; Nishi, Y.; Nakanishi, S.

    2013-12-01

    An appropriate monitoring program is indispensable for an individual geologic storage project to aid in answering various operational questions by detecting changes within the reservoir and to provide early warning of potential CO2 leakage through the caprock. Such a program is also essential to reduce uncertainties associated with reservoir parameters and to improve the predictive capability of reservoir models. Repeat geophysical measurements performed at the earth surface show particular promise for monitoring large subsurface volumes. To appraise the utility of geophysical techniques, Ishido et al. carried out numerical simulations of an aquifer system underlying a portion of Tokyo Bay and calculated the temporal changes in geophysical observables caused by changing underground conditions as computed by reservoir simulation (Energy Procedia, 2011). They used 'geophysical postprocessors' to calculate the resulting temporal changes in the earth-surface distributions of microgravity, self-potential (SP), apparent resistivity (from MT surveys) and seismic observables. The applicability of any particular method is likely to be highly site-specific, but these calculations indicate that none of these techniques should be ruled out altogether. Some survey techniques (gravity, MT resistivity) appear to be suitable for characterizing long-term changes, whereas others (seismic reflection, SP) are quite responsive to short term disturbances. The self-potential postprocessor calculates changes in subsurface electrical potential induced by pressure disturbances through electrokinetic coupling (Ishido & Pritchett, JGR 1999). In addition to electrokinetic coupling, SP anomalies may be generated by various other mechanisms such as thermoelectric coupling, electrochemical diffusion potential, etc. In particular, SP anomalies of negative polarity, which are frequently observed near wells, appear to be caused by an underground electrochemical mechanism similar to a galvanic cell

  2. Active fire monitoring and fire danger potential detection from space: A review

    Institute of Scientific and Technical Information of China (English)

    John J. QU; Wanting WANG; Swarvanu DASGUPTA; Xianjun HAO

    2008-01-01

    Wildland fire is both one of the major natural hazards and a natural process for ecosystem persistence. Accurate assessment of fire danger potential and timely detection of active fires are critical for fire fighting and fuel management. Space-borne measurements have become the primary approaches for these efforts. Many research works have been conducted and some data pro-ducts have been generated for practical applications. This paper presents a review of the major sensors and algo-rithms for active fire monitoring and fire danger potential detection from space. Major sensors and their character-istics, physical principles of the major algorithms are sum-marized. Limitations of these algorithms and future improvements are also discussed.

  3. Stem Water Potential Monitoring in Pear Orchards through WorldView-2 Multispectral Imagery

    Directory of Open Access Journals (Sweden)

    Jonathan Van Beek

    2013-12-01

    Full Text Available Remote sensing can provide good alternatives for traditional in situ water status measurements in orchard crops, such as stem water potential (Ψstem. However, the heterogeneity of these cropping systems causes significant differences with regards to remote sensing products within one orchard and between orchards. In this study, robust spectral indicators of Ψstem were sought after, independent of sensor viewing geometry, orchard architecture and management. To this end, Ψstem was monitored throughout three consecutive growing seasons in (deficit irrigated and rainfed pear orchards and related to spectral observations of leaves, canopies and WorldView-2 imagery. On a leaf and canopy level, high correlations were observed between the shortwave infrared reflectance and in situ measured Ψstem. Additionally, for canopy measurements, visible and near-infrared wavelengths (R530/R600, R530/R700 and R720/R800 showed significant correlations. Therefore, the Red-edge Normalized Difference Vegetation Index (ReNDVI was applied on fully sunlit satellite imagery and found strongly related with Ψstem (R2 = 0.47; RMSE = 0.36 MPa, undoubtedly showing the potential of WorldView-2 to monitor water stress in pear orchards. The relationship between ReNDVI and Ψstem was independent of management, irrigation setup, phenology and environmental conditions. In addition, results showed that this relation was also independent of off-nadir viewing angle and almost independent of viewing geometry, as the correlation decreased after the inclusion of fully shaded scenes. With further research focusing on issues related to viewing geometry and shadows, high spatial water status monitoring with space borne remote sensing is achievable.

  4. Monitoring Genetic and Metabolic Potential for In-Situ Bioremediation: Mass Spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    Buchanan, Michelle V.; Britt, Phillip F.; Doktycz, Mitchel J.; Hurst, Gregory B.; Lidstrom, Mary E.

    2000-06-01

    A number of DOE sites are contaminated with dense non-aqueous phase liquids (DNAPLs) such as carbon tetrachloride and trichloroethylene. At many of these sites, microbial bioremediation is an attractive strategy for cleanup, since it has the potential to degrade DNAPLs in situ. A rapid screening method to determine the broad range potential of a site's microbial population for contaminant degradation would greatly facilitate assessment for in situ bioremediation, as well as for monitoring ongoing bioremediation treatment. Current laboratory-based treatability methods are cumbersome and expensive. In this project, we are developing methods based on matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) for rapid and accurate detection of polymerase chain reaction (PCR) products from microbial genes involved in biodegradation of pollutants. PCR primers are being developed to amplify DNA sequences that are amenable to MALDI-MS detection. This work will lay the foundation for development of a field-portable MS-based technique for rapid on site assessment and monitoring of bioremediation processes.

  5. Microbial Monitoring of Pathogens by Comparing Multiple Real-Time PCR Platforms for Potential Space Applications

    Science.gov (United States)

    Birmele, Michele

    2012-01-01

    The International Space Station (ISS) is a closed environment wih rotations of crew and equipment each introducing their own microbial flora making it necessary to monitor the air, surfaces, and water for microbial contamination. Current microbial monitoring includes labor and time intensive methods to enumerate total bacterial and fungal cells with limited characterization during in-flight testing. Although this culture-based method has been sufficient for monitoring the ISS, future long duration missions will need to perform more comprehensive characterization in-flight, since sample return and ground characterization may not be available. A workshop was held in 2011 at the Johnson Space Center to discuss alternative methodologies and technologies suitable for microbial monitoring for these longterm exploration missions where molecular-based methodologies, such as polymerase chain reaction (PCR), were recommended. In response, a multi-center (Marshall Space Flight Center, Johnson Space Center, Jet Propulsion Laboratory, and Kennedy Space Center) collaborative research effort was initiated to explore novel commercial-off-the-shelf hardware options for spaceflight environmental monitoring. The goal was to evaluate quantitative/semi-quantitative PCR approaches to space applications for low cost in-flight rapid identification of microorganisms affecting crew safety. The initial phase of this project identified commercially available platforms that could be minimally modified to perform nominally in microgravity followed by proof-of-concept testing on the highest qualifying candidates with a universally available test organism, Salmonella enterica. The platforms evaluated during proof-of-concept testing included the iCubate 2.0(TradeMark) (iCubate, Huntsville, AL), RAZOR EX (BioFire Diagnostics; Salt Lake City, Utah) and SmartCycler(TradeMark) (Cepheid; Sunnyvale, CA). The analysis identified two potential technologies (iCubate 2.0 and RAZOR EX) that were able to

  6. Usefulness of intraoperative monitoring of visual evoked potentials in transsphenoidal surgery.

    Science.gov (United States)

    Kamio, Yoshinobu; Sakai, Naoto; Sameshima, Tetsuro; Takahashi, Goro; Koizumi, Shinichiro; Sugiyama, Kenji; Namba, Hiroki

    2014-01-01

    Postoperative visual outcome is a major concern in transsphenoidal surgery (TSS). Intraoperative visual evoked potential (VEP) monitoring has been reported to have little usefulness in predicting postoperative visual outcome. To re-evaluate its usefulness, we adapted a high-power light-stimulating device with electroretinography (ERG) to ascertain retinal light stimulation. Intraoperative VEP monitoring was conducted in TSSs in 33 consecutive patients with sellar and parasellar tumors under total venous anesthesia. The detectability rates of N75, P100, and N135 were 94.0%, 85.0%, and 79.0%, respectively. The mean latencies and amplitudes of N75, P100, and N135 were 76.8 ± 6.4 msec and 4.6 ± 1.8 μV, 98.0 ± 8.6 msec and 5.0 ± 3.4 μV, and 122.1 ± 16.3 msec and 5.7 ± 2.8 μV, respectively. The amplitude was defined as the voltage difference from N75 to P100 or P100 to N135. The criterion for amplitude changes was defined as a > 50% increase or 50% decrease in amplitude compared to the control level. The surgeon was immediately alerted when the VEP changed beyond these thresholds, and the surgical manipulations were stopped until the VEP recovered. Among the 28 cases with evaluable VEP recordings, the VEP amplitudes were stable in 23 cases and transiently decreased in 4 cases. In these 4 cases, no postoperative vision deterioration was observed. One patient, whose VEP amplitude decreased without subsequent recovery, developed vision deterioration. Intraoperative VEP monitoring with ERG to ascertain retinal light stimulation by the new stimulus device was reliable and feasible in preserving visual function in patients undergoing TSS.

  7. Spectral induced polarization and electrodic potential monitoring of microbially mediated iron sulfide transformations

    Energy Technology Data Exchange (ETDEWEB)

    Hubbard, Susan; Personna, Y.R.; Ntarlagiannis, D.; Slater, L.; Yee, N.; O' Brien, M.; Hubbard, S.

    2008-02-15

    Stimulated sulfate-reduction is a bioremediation technique utilized for the sequestration of heavy metals in the subsurface.We performed laboratory column experiments to investigate the geoelectrical response of iron sulfide transformations by Desulfo vibriovulgaris. Two geoelectrical methods, (1) spectral induced polarization (SIP), and (2) electrodic potential measurements, were investigated. Aqueous geochemistry (sulfate, lactate, sulfide, and acetate), observations of precipitates (identified from electron microscopy as iron sulfide), and electrodic potentials on bisulfide ion (HS) sensitive silver-silver chloride (Ag-AgCl) electrodes (630 mV) were diagnostic of induced transitions between an aerobic iron sulfide forming conditions and aerobic conditions promoting iron sulfide dissolution. The SIP data showed 10m rad anomalies during iron sulfide mineralization accompanying microbial activity under an anaerobic transition. These anomalies disappeared during iron sulfide dissolution under the subsequent aerobic transition. SIP model parameters based on a Cole-Cole relaxation model of the polarization at the mineral-fluid interface were converted to (1) estimated biomineral surface area to pore volume (Sp), and (2) an equivalent polarizable sphere diameter (d) controlling the relaxation time. The temporal variation in these model parameters is consistent with filling and emptying of pores by iron sulfide biofilms, as the system transitions between anaerobic (pore filling) and aerobic (pore emptying) conditions. The results suggest that combined SIP and electrodic potential measurements might be used to monitor spatiotemporal variability in microbial iron sulfide transformations in the field.

  8. Spectral induced polarization and electrodic potential monitoring of microbially mediated iron sulfide transformations

    Science.gov (United States)

    Personna, Yves Robert; Ntarlagiannis, Dimitrios; Slater, Lee; Yee, Nathan; O'Brien, Michael; Hubbard, Susan

    2008-06-01

    Stimulated sulfate-reduction is a bioremediation technique utilized for the sequestration of heavy metals in the subsurface. We performed laboratory column experiments to investigate the geoelectrical response of iron sulfide transformations by Desulfovibrio vulgaris. Two geoelectrical methods, (1) spectral induced polarization (SIP), and (2) electrodic potential measurements, were investigated. Aqueous geochemistry (sulfate, lactate, sulfide, and acetate), observations of precipitates (identified from electron microscopy as iron sulfide), and electrodic potentials on bisulfide ion (HS-) sensitive silver-silver chloride (Ag-AgCl) electrodes (˜-630 mV) were diagnostic of induced transitions between anaerobic iron sulfide forming conditions and aerobic conditions promoting iron sulfide dissolution. The SIP data showed ˜10 mrad anomalies during iron sulfide mineralization accompanying microbial activity under an anaerobic transition. These anomalies disappeared during iron sulfide dissolution under the subsequent aerobic transition. SIP model parameters based on a Cole-Cole relaxation model of the polarization at the mineral-fluid interface were converted to (1) estimated biomineral surface area to pore volume (Sp), and (2) an equivalent polarizable sphere diameter (d) controlling the relaxation time. The temporal variation in these model parameters is consistent with filling and emptying of pores by iron sulfide biofilms, as the system transitions between anaerobic (pore filling) and aerobic (pore emptying) conditions. The results suggest that combined SIP and electrodic potential measurements might be used to monitor spatiotemporal variability in microbial iron sulfide transformations in the field.

  9. Clinical expert panel on monitoring potential lung toxicity of inhaled oligonucleotides: consensus points and recommendations.

    Science.gov (United States)

    Alton, Eric W; Boushey, Homer A; Garn, Holger; Green, Francis H; Hodges, Michael; Martin, Richard J; Murdoch, Robert D; Renz, Harald; Shrewsbury, Stephen B; Seguin, Rosanne; Johnson, Graham; Parry, Joel D; Tepper, Jeff; Renzi, Paolo; Cavagnaro, Joy; Ferrari, Nicolay

    2012-08-01

    Oligonucleotides (ONs) are an emerging class of drugs being developed for the treatment of a wide variety of diseases including the treatment of respiratory diseases by the inhalation route. As a class, their toxicity on human lungs has not been fully characterized, and predictive toxicity biomarkers have not been identified. To that end, identification of sensitive methods and biomarkers that can detect toxicity in humans before any long term and/or irreversible side effects occur would be helpful. In light of the public's greater interests, the Inhalation Subcommittee of the Oligonucleotide Safety Working Group (OSWG) held expert panel discussions focusing on the potential toxicity of inhaled ONs and assessing the strengths and weaknesses of different monitoring techniques for use during the clinical evaluation of inhaled ON candidates. This white paper summarizes the key discussions and captures the panelists' perspectives and recommendations which, we propose, could be used as a framework to guide both industry and regulatory scientists in future clinical research to characterize and monitor the short and long term lung response to inhaled ONs.

  10. Measuring microchannel electroosmotic mobility and zeta potential by the current monitoring method.

    Science.gov (United States)

    Shao, Chenren; Devoe, Don L

    2013-01-01

    Electroosmotic flow (EOF) is an electrokinetic flow control technique widely used in microfluidic systems for applications including direct electrokinetic pumping, hydrodynamic pressure generation, and counterflow for microfluidic separations. During EOF, an electric field is applied along the length of a microchannel containing an electrolyte, with mobile ions near the charged microchannel walls experiencing a Coulomb force due to electrostatic interactions with the applied electric field that leads to bulk solution movement. The goal of this laboratory is to experimentally determine the fixed channel surface charge (zeta potential) and electroosmotic mobility associated with a given microchannel substrate material and buffer solution, using a simple current monitoring method to measure the average flow velocity within the microchannel. It is a straightforward experiment designed to help students understand EOF physics while gaining hands-on experience with basic world-to-chip interfacing. It is well suited to a 90-min laboratory session for up to 12 students with minimal infrastructure requirements.

  11. The rising demand for energy: a potential for optical fiber sensors in the monitoring sector

    Science.gov (United States)

    Bosselmann, Thomas; Willsch, Michael; Ecke, Wolfgang

    2008-03-01

    For a long time electric power was taken as a natural unlimited resource. With globalization the demand for energy has risen. This has brought rising prices for fossil fuels, as well as a diversification of power generation. Besides conventional fossil, nuclear plants are coming up again. Renewable energy sources are gaining importance resulting in recent boom of wind energy plants. In the past reliability and availability and an extremely long lifetime were of paramount importance. Today this has been added by cost, due to the global competition and the high fuel costs. New designs of power components have increased efficiency using lesser material. Higher efficiency causes inevitably higher stress on the materials, of which the machines are built. As a reduction of lifetime is not acceptable and maintenance costs are expected to be at a minimum, condition monitoring systems are going to being used now. This offers potentials for fiber optic sensor applications.

  12. Geothermal reservoir monitoring by continuous self-potential measurements, Mori geothermal field, Japan

    Energy Technology Data Exchange (ETDEWEB)

    Yasukawa, Kasumi; Ishido, Tsuneo [Geological Survey of Japan, AIST, Central 7, Tsukuba, Ibaraki 305-8567 (Japan); Suzuki, Iwao [JMC Geothermal Engineering Co. Ltd, Iwate (Japan)

    2005-10-01

    A self-potential (SP) monitoring study was conducted at the Mori geothermal field, Japan, to detect fluid flow changes in the reservoir caused by well operations. In 2000, eight observation points were deployed in and around the reservoir region for about 2.5 months, during which the production and reinjection wells were shut in and then re-opened. Since no reliable remote reference was available, the SP results were plotted in two ways: adopting an observation point in the target area as reference, and using the average value of all the observation points as a reference (called the 'relative SP' plot). Although changes in SP corresponding to well operations were detected in both plots, more reliable results were obtained with the relative SP plot. Based on numerical simulation of SP using a simplified model of the Mori reservoir, the observed changes are interpreted as being caused by reservoir pressure changes through electrokinetic coupling. (author)

  13. Local seismic network for monitoring of a potential nuclear power plant area

    Science.gov (United States)

    Tiira, Timo; Uski, Marja; Kortström, Jari; Kaisko, Outi; Korja, Annakaisa

    2016-04-01

    This study presents a plan for seismic monitoring of a region around a potential nuclear power plant. Seismic monitoring is needed to evaluate seismic risk. The International Atomic Energy Agency has set guidelines on seismic hazard evaluation and monitoring of such areas. According to these guidelines, we have made a plan for a local network of seismic stations to collect data for seismic source characterization and seismotectonic interpretations, as well as to monitor seismic activity and natural hazards. The detection and location capability of the network were simulated using different station configurations by computing spatial azimuthal coverages and detection threshold magnitudes. Background noise conditions around Pyhäjoki were analyzed by comparing data from different stations. The annual number of microearthquakes that should be detected with a dense local network centered around Pyhäjoki was estimated. The network should be dense enough to fulfill the requirements of azimuthal coverage better than 180° and automatic event location capability down to ML ˜ 0 within a distance of 25 km from the site. A network of 10 stations should be enough to reach these goals. With this setup, the detection threshold magnitudes are estimated to be ML = -0.1 and ML = 0.1 within a radius of 25 and 50 km from Pyhäjoki, respectively. The annual number of earthquakes detected by the network is estimated to be 2 (ML ≥ ˜ -0.1) within 25 km radius and 5 (ML ≥ ˜-0.1 to ˜0.1) within 50 km radius. The location accuracy within 25 km radius is estimated to be 1-2 and 4 km for horizontal coordinates and depth, respectively. Thus, the network is dense enough to map out capable faults with horizontal accuracy of 1-2 km within 25 km radius of the site. The estimation is based on the location accuracies of five existing networks in northern Europe. Local factors, such as seismic noise sources, geology and infrastructure might limit the station configuration and detection and

  14. An evaluation of commercial NDIR sensors for a potential use in future urban GHG monitoring systems

    Science.gov (United States)

    Arzoumanian, E.; Bastos, A.; Gaynullin, B.; Martin, H.; Hjern, L.; Laurent, O.; Vogel, F. R.

    2016-12-01

    Cities are a key contributor to climate change, as urban activities are major sources of GHG emissions. It is clear that accurate estimates of the magnitude of anthropogenic and natural urban emissions are needed to assess their influence on the carbon balance. Recently Wu et al. (2016) suggested that a denser ground-based GHG monitoring network in Paris would have the potential allow retrieving sector specific GHG emission estimates (and potentially in certain other cities) when combined with an atmospheric inversion framework using reasonably accurate observations (ca. 1 ppm for hourly means). One major barrier for such denser observations can be the high cost of high-precision instruments or high calibration cost of cheaper, unstable instrumentation. Within a recent climate KIC project, LSCE and SenseAir AB have worked on novel inexpensive NDIR sensors for CO2 measurements for site and city-scale applications that fulfil typical repeatability and reproducibility requirements necessary for this task. We conducted laboratory tests on six prototypes and determined the sensitivity of the sensors to multiple parameters, e.g. changing pressure, temperature and water vapor. Also, we developed a correction and calibration strategy for our NDIR sensors. Furthermore, we fully integrated these NDIR sensors in a platform containing the CO2sensor, pressure and temperature sensors, gas supply pump and a fully automated data acquisition unit. This platform was deployed in parallel to Picarro G2401 instruments in the urban network of LSCE. In this field experiment, using weekly calibration, we find a root-mean-square difference of less than 1 ppm for hourly mean concentrations at the semi-urban site in Saclay and the urban site of Jussieu, Paris, France. Our recent results concerning sensor testing and CO2monitoring from the two sites sited above also guide our recommendations for a low cost urban environmental monitoring system based on open source hardware (Raspberry Pi) and

  15. FloTrac/Vigileo系统在单肺通气心输出量监测中应用的探讨%Investigation of FloTrac/Vigileo in monitoring cardiac output during one lung ventilation

    Institute of Scientific and Technical Information of China (English)

    王宏宇; 苏中宏; 史宏伟; 鲍红光

    2011-01-01

    观察FloTrac/Vigileo系统在单肺通气心输出量(CO)监测中的应用效果.方法择期单肺通气手术患者17例,ASAⅡ或Ⅲ级,使用FloTrac/Vigileo系统观察CO变化,记录诱导后(T0)、单肺通气5 min(T1)、10 min(T2)、30min(T3)以及双腔管双肺通气时(T4)、关胸时(T5)的HR、MAP、心脏指数(CI)、每搏量变异度(SVV)和气道峰压(Pmax).结果 与T0时比较,T1、T5时CI明显增加(P<0.05);T1~T5时SVV均明显下降(P<0.05);T1~T3时Pmax显著增加(P<0.05).结论 FloTrac/Vigileo系统能快速、持续地监测单肺通气时CO的变化.%Objective To investigate the efficacy of FloTrac/Vigileo in monitoring cardiac output during one lung ventilatioa Methods Seventeen ASA Ⅱ or Ⅲ patients requiring one lung ventilation (OLV) were enrolled in the study. Cardiac index (CD and stroke volume variation (SVV) were recorded using FloTrac/Vigileo after anesthesia induction (T0), 5 min after (T1), 10 min after (T2), 30 min after (T3) OLV, during double-lumen-endobronchial-tube ventilation (T4) and at closing thorax (T5). HR, MAP and airway pressure were also recorded at these time points. Results Compared with T0, CI increased significantly at T1 and T5 (P<0. 05); SW decreased significantly from T1 to T5 (P<0. 05); and Pmax increased significantly from T1 to T3 (P<0. 05). Conclusion FloTrac/Vigileo can be used to rapidly and continuously monitor cardiac output during one lung ventilation continuously.

  16. Fluid flow monitoring in oilfields using downhole measurements of electrokinetic potential

    Science.gov (United States)

    Jackson, M. D.; Saunders, J. H.; Pain, C. C.

    2006-12-01

    Permanently installed downhole sensors are increasingly being deployed to provide `real-time' reservoir data during hydrocarbon production, which helps to reduce uncertainty in the reservoir description and contributes to reservoir management decisions. Where wells are equipped with inflow control valves (so called `intelligent' wells), it is possible to develop a feedback loop between measurement and control to optimize production. We suggest that measurements of electrokinetic potential during production, using permanently installed downhole electrodes, could be used to detect water encroachment towards an intelligent oil well. Downhole electrodes mounted at the production well on the outside of insulated casing, have been successfully applied in subsurface resistivity surveys during oil production. Similar technology could be used to measure electrokinetic potential. Moreover, recent and ongoing work has changed our understanding of electrokinetic coupling under two-phase conditions. We present the results of numerical simulations of fluid movement during hydrocarbon production, using a new formulation which captures both the changing fluid distributions and the resulting electrical potentials. We suggest that encroaching water causes changes in electrokinetic potential at the production well which could be resolved above background electrical noise; indeed, changes in water saturation could be detected several 10's to 100's of metres away from the well. This contrasts with most other downhole monitoring techniques, which sample only the region immediately adjacent to the wellbore. Signal resolution is improved if the water has a relatively low salinity, and the pressure gradient into the well is large. However, significant uncertainties remain concerning the nature of electrokinetic coupling during the flow of oil and water, particularly in mixed and oil-wet reservoirs.

  17. In-situ monitoring of potential enhanced DNA related processes using electrochemical quartz crystal microbalance with dissipation (EQCM-D)

    DEFF Research Database (Denmark)

    Quan, Xueling; Heiskanen, Arto; Tenje, Maria

    2014-01-01

    The effect of applied potential pulses on DNA functionalization (thiolated single stranded DNA) and hybridization processes has been monitored in-situ on gold surfaces using electrochemical quartz crystal microbalance with dissipation (EQCM-D). The applied potentials were chosen with respect to t...

  18. Lipidomics: potential role in risk prediction and therapeutic monitoring for diabetes and cardiovascular disease.

    Science.gov (United States)

    Meikle, Peter J; Wong, Gerard; Barlow, Christopher K; Kingwell, Bronwyn A

    2014-07-01

    Lipidomics has developed rapidly over the past decade to the point where clinical application may soon be possible. Developments including high throughput technologies enable the simultaneous quantification of several hundred lipid species, thereby providing a global assessment of lipid metabolism. Given the key role of lipids in the pathophysiology of diabetes and cardiovascular disease, lipidomics has the potential to: i) Significantly improve prediction of future disease risk, ii) Inform on mechanisms of disease pathogenesis, iii) Identify patient groups responsive to particular therapies and iv) More closely monitor response to therapy. Lipidomic analyses of both whole plasma and lipoprotein subfractions are integral to the current initiative to understand the relationships between lipoprotein composition and function and how these are affected by disease and treatment. This approach will not only aid in appropriate targeting of existing lipid lowering therapies such as statins and fibrates, but will be important in unravelling the controversies surrounding HDL-based therapies which have failed in clinical trials to date. The ultimate utility of lipidomics to clinical practice will depend firstly on the ability of risk prediction models incorporating lipidomic parameters to significantly improve upon conventional clinical risk markers in predicting future disease risk. Secondly, for widespread application, lipidomic-based measurements must be practical and accessible through standard pathology laboratories. This review will cover developments in lipidomics including methodology, bioinformatics/statistics, insights into disease pathophysiology, the effect of therapeutic interventions, the role of large clinical outcome trials in validating lipidomic approaches to patient management and potential applications in clinical practice.

  19. Hemisection spinal cord injury in rat: The value of intraoperative somatosensory evoked potential monitoring

    Science.gov (United States)

    Cloud, Beth A.; Ball, Bret G.; Chen, Bingkun; Knight, Andrew M.; Hakim, Jeffrey S.; Ortiz, Ana M.; Windebank, Anthony J.

    2012-01-01

    Techniques used to produce partial spinal cord injuries in animal models have the potential for creating variability in lesions. The amount of tissue affected may influence the functional outcomes assessed in the animals. The recording of somatosensory evoked potentials (SSEPs) may be a valuable tool for assessing the extent of lesion applied in animal models of traumatic spinal cord injury (SCI). Intraoperative tibial SSEP recordings were assessed during surgically induced lateral thoracic hemisection SCI in Sprague-Dawley rats. The transmission of SSEPs, or lack thereof, was determined and compared against the integrity of the dosal funiculi on each side of the spinal cord upon histological sectioning. An association was found between the presence of an SSEP signal and presence of intact dorsal funiculus tissue. The relative risk is 4.50 (95% confidence interval: 1.83 to 11.08) for having an intact dorsal funiculus when the ipsilateral SSEP was present compared to when it was absent. Additionally, the amount of spared spinal cord tissue correlates with final functional assessments at nine weeks post injury: BBB (linear regression, R2 = 0.618, p <0.001) and treadmill test (linear regression, R2 = 0.369, p = 0.016). Therefore, we propose intraoperative SSEP monitoring as a valuable tool to assess extent of lesion and reduce variability between animals in experimental studies of SCI. PMID:22960163

  20. Monitoring genetic and metabolic potential for in situ bioremediation: Mass spectrometry. 1998 annual progress report

    Energy Technology Data Exchange (ETDEWEB)

    Buchanan, M.V.; Hurst, G.B.; Doktycz, M.J.; Britt, P.F.; Weaver, K. [Oak Ridge National Lab., TN (US); Lidstrom, M.; Costello, A. [Univ. of Washington, Seattle, WA (US)

    1998-01-01

    'A number of DOE sites are contaminated with dense non-aqueous phase liquids (DNAPLs) such as carbon tetrachloride and trichloroethylene. At many of these sites, microbial bioremediation is an attractive strategy for cleanup, since it has the potential to degrade DNAPLs in-situ. A rapid screening method to determine the broad range potential of a site''s microbial population for contaminant degradation would greatly facilitate assessment for in-situ bioremediation, as well as for monitoring ongoing bioremediation treatment. Current laboratory-based treatability methods are cumbersome and expensive. In this project, the authors are developing methods based on matrix-assisted laser desorption/ ionization mass-spectrometry (MALDI-MS) to rapidly and accurately detect polymerase chain reaction (PCR) products. In parallel, PCR primers to amplify DNA sequences from microbial genes involved in biodegradation of pollutants are being identified that are short enough to allow MALDI-MS detection. This work will lay the foundation for development of a field-portable MS-based technique for rapid assessment and monitoring of bioremediation processes on site. This report summarizes work after 1-1/2 years of a 3-year project. In this time, the authors have demonstrated MALDI-MS-based detection of signature bacterial PCR products (Hurst et al., 1998). A model system for interfacing MALDI-MS with PCR amplification is based on the pmoA gene for the active site subunit of particulate methane monooxygenase, a bacterial enzyme that can oxidize trichloroethylene. PCR primer pairs were designed to amplify relatively short segments (99 bases and 56 bases) of this gene in Type 1 and Type 2 methanotrophs. A rapid reverse-phase purification of the resulting PCR products allows MALDI-MS detection from a fraction of one 25-microliter PCR reaction. At this level of sensitivity, MALDI-MS has considerable potential to compete with existing electrophoresis and hybridization methods

  1. Output hardcopy devices

    CERN Document Server

    Durbeck, Robert

    1988-01-01

    Output Hardcopy Devices provides a technical summary of computer output hardcopy devices such as plotters, computer output printers, and CRT generated hardcopy. Important related technical areas such as papers, ribbons and inks, color techniques, controllers, and character fonts are also covered. Emphasis is on techniques primarily associated with printing, as well as the plotting capabilities of printing devices that can be effectively used for computer graphics in addition to their various printing functions. Comprised of 19 chapters, this volume begins with an introduction to vector and ras

  2. Flash visual evoked potential monitoring of optic tract function during macroelectrode-based pallidotomy.

    Science.gov (United States)

    Bonaroti, E A; Rose, R D; Kondziolka, D; Baser, S; Lunsford, L D

    1997-03-15

    Posteroventral pallidotomy (PVP) has received renewed interest as an ablative procedure for the symptomatic treatment of Parkinson's disease. In previous reports, the proximity of the optic tract to the lesion target in the globus pallidus internus has resulted in the occurrence of visual field deficits in as much as 14% of patients. The authors have used intraoperative visual evoked potentials (VEPs) during PVP to reduce this risk. All procedures were performed in awake patients. Flash stimuli were delivered to each eye via fiberoptic sources. Baseline flash VEPs were recorded at O1/Cz (left visual cortex to vertex), Oz/Cz (midline visual cortex to vertex), and O2/Cz (right visual cortex to vertex) for OS, OU, and OD stimulation. Epochs were acquired before and after localization, after macroelectrode stimulation, after temporary thermal lesioning, and after permanent thermal lesioning. Forty-seven patients underwent a total of 59 procedures. Visual evoked potentials were recorded reproducibly in all patients. In 11 procedures, VEP changes were reported, including six amplitude changes (10-80%), six latency shifts (3-10 msec), and one report of "variability." In four procedures, VEP changes prompted a change in target coordinates. One false-positive and one false-negative VEP change were encountered. The only confirmed visual deficit was a superior quadrantanopsia, present on formal fields, but clinically asymptomatic. The authors conclude that VEPs may be useful for procedures performed in the awake patient because of the lack of anesthetic-induced variability. The 1.7% visual morbidity reported here (one in 59 patients) compares favorably with other series using microelectrodes. Visual evoked potentials may be a useful monitoring technique to reduce the incidence of clinically significant visual morbidity during pallidotomy, especially during formal lesioning of the ventral pallidum adjacent to the optic tract.

  3. Potential of Multitemporal Tandem-X Derived Crop Surface Models for Maize Growth Monitoring

    Science.gov (United States)

    Hütt, C.; Tilly, N.; Schiedung, H.; Bareth, G.

    2016-06-01

    In this study, first results of retrieving plant heights of maize fields from multitemporal TanDEM-X images are shown. Three TanDEM-X dual polarization spotlight acquisitions were taken over a rural area in Germany in the growing season 2014. By interferometric processing, digital terrain models (DTM) were derived for each date with 5m resolution. From the data of the first acquisition (June 1st) taken before planting, a DTM of the bare ground is generated. The data of the following acquisition dates (July 15th, July 26th) are used to establish crop surface models (CSM). A CSM represents the crop surface of a whole field in a high resolution. By subtracting the DTM of the ground from each CSM, the actual plant height is calculated. Within these data sets 30 maize fields in the area of interest could be detected and verified by external land use data. Besides the spaceborne measurements, one of the maize fields was intensively investigated using terrestrial laser scanning (TLS), which was carried out at the same dates as the predicted TanDEM-X acquisitions. Visual inspection of the derived plant heights, and accordance of the individually processed polarisations over the maize fields, demonstrate the feasibility of the proposed method. Unfortunately, the infield variability of the intensively monitored field could not be successfully captured in the TanDEM-X derived plant heights and merely the general trend is visible. Nevertheless, the study shows the potential of the TanDEM-X constellation for maize height monitoring on field level.

  4. A Study on the Potential Applications of Satellite Data in Air Quality Monitoring and Forecasting

    Science.gov (United States)

    Li, Can; Hsu, N. Christina; Tsay, Si-Chee

    2011-01-01

    In this study we explore the potential applications of MODIS (Moderate Resolution Imaging Spectroradiometer) -like satellite sensors in air quality research for some Asian regions. The MODIS aerosol optical thickness (AOT), NCEP global reanalysis meteorological data, and daily surface PM(sub 10) concentrations over China and Thailand from 2001 to 2009 were analyzed using simple and multiple regression models. The AOT-PM(sub 10) correlation demonstrates substantial seasonal and regional difference, likely reflecting variations in aerosol composition and atmospheric conditions, Meteorological factors, particularly relative humidity, were found to influence the AOT-PM(sub 10) relationship. Their inclusion in regression models leads to more accurate assessment of PM(sub 10) from space borne observations. We further introduced a simple method for employing the satellite data to empirically forecast surface particulate pollution, In general, AOT from the previous day (day 0) is used as a predicator variable, along with the forecasted meteorology for the following day (day 1), to predict the PM(sub 10) level for day 1. The contribution of regional transport is represented by backward trajectories combined with AOT. This method was evaluated through PM(sub 10) hindcasts for 2008-2009, using ohservations from 2005 to 2007 as a training data set to obtain model coefficients. For five big Chinese cities, over 50% of the hindcasts have percentage error less than or equal to 30%. Similar performance was achieved for cities in northern Thailand. The MODIS AOT data are responsible for at least part of the demonstrated forecasting skill. This method can be easily adapted for other regions, but is probably most useful for those having sparse ground monitoring networks or no access to sophisticated deterministic models. We also highlight several existing issues, including some inherent to a regression-based approach as exemplified by a case study for Beijing, Further studies will be

  5. Intraoperative tractography and motor evoked potential (MEP) monitoring in surgery for gliomas around the corticospinal tract.

    Science.gov (United States)

    Maesawa, Satoshi; Fujii, Masazumi; Nakahara, Norimoto; Watanabe, Tadashi; Wakabayashi, Toshihiko; Yoshida, Jun

    2010-07-01

    Our goal is to indicate the importance of combining intraoperative tractography with motor-evoked potential (MEP) monitoring for glioma surgery in motor eloquent areas. Tumor removal was performed in 28 patients with gliomas in and around the corticospinal tract (CST), in an operation theater equipped with an integrated high-field intraoperative magnetic resonance imaging and a neuronavigation system. Diffusion-tensor imaging-based tractography of the CST was implemented preoperatively and intraoperatively. When the surgically manipulated area came close to the corticospinal pathway, MEP responses were elicited by subcortical stimulation. Responsive areas were compared with the locations of fibers traced by preoperative and intraoperative tractography. Imaging and functional outcomes were reviewed. Intraoperative tractography demonstrated significant inward or outward shift during surgery. MEP responses were observed around the tract at various intensities, and the distance between MEP responsive sites and intraoperative tractography was significantly correlated with the stimulation intensity (P < 0.01). The distance from preoperative tractography was not correlated. A more than subtotal resection was achieved in 24 patients (85.7%). Transient motor deterioration was seen in 12 patients (42.8%), and a permanent deficit was seen in 1 patient (3.5%). We found that intraoperative tractography demonstrated the location of the CST more accurately than preoperative tractography. The results of the linear regression between distance and stimulation intensity were informative for guiding approaches to tumor remnants without impinging on the CST. The combination of intraoperative tractography and MEP monitoring can enhance the quality of surgery for gliomas in motor eloquent areas. Copyright © 2010 Elsevier Inc. All rights reserved.

  6. Human enteric viruses–potential indicators for enhanced monitoring of recreational water quality

    Institute of Scientific and Technical Information of China (English)

    Erin; Allmann; Updyke; Zi; Wang; Si; Sun; Christina; Connell; Marek; Kirs; Mayee; Wong; Yuanan; Lu

    2015-01-01

    Recreational waters contaminated with human fecal pollution are a public health concern, and ensuring the safety of recreational waters for public use is a priority of both the Environmental Protection Agency(EPA) and the Centers for Disease Control and Prevention(CDC). Current recreational water standards rely on fecal indicator bacteria(FIB) levels as indicators of human disease risk. However present evidence indicates that levels of FIB do not always correspond to the presence of other potentially harmful organisms, such as viruses. Thus, enteric viruses are currently tested as water quality indicators, but have yet to be successfully implemented in routine monitoring of water quality. This study utilized enteric viruses as possible alternative indicators of water quality to examine 18 different fresh and offshore recreational waters on O‘ahu, Hawai‘i, by using newly established laboratory techniques including highly optimized PCR, real time PCR, and viral infectivity assays. All sample sites were detected positive for human enteric viruses by PCR including enterovirus, norovirus genogroups I and II, and male specific FRNA coliphage. A six time-point seasonal study of enteric virus presence indicated significant variation in virus detection between the rainy and dry seasons. Quantitative PCR detected the presence of norovirus genogroup II at levels at which disease risk may occur, and there was no correlation found between enteric virus presence and FIB counts. Under the present laboratory conditions, no infectious viruses were detected from the samples PCR-positive for enteric viruses. These data emphasize both the need for additional indicators for improved monitoring of water quality, and the feasibility of using enteric viruses as these indicators.

  7. Baseline for Monitoring Water Resources Along Kabul and Indus Rivers of Pakistan for Potential Terrorist Contamination

    Science.gov (United States)

    Hamidullah, S.; Tariq, S.; Shah, M. T.; Bishop, M. P.; Kamp, U.; Olsenholler, J.

    2002-05-01

    Baseline for Monitoring Water Resources Along Kabul and Indus Rivers of Pakistan for Potential Terrorist Contamination Terrorism has temporarily constrained the dynamism of the world it was enjoying before September 11, 2001, but also has opened avenues for people of all ethnicities, creeds, and professions to join hands in combating it. Scientific efforts to combat terrorism are likely to lead to better use of existing scientific knowledge as well as to discoveries that will increase world organization, interconnectivity, and peace promotion. Afghanistan and surrounding regions are major focal points for current anti-terrorist activities of the USA and its allies, including Pakistan. The United States, Pakistan, and Afghanistan have shared many similar political objectives, as well as differences, in cold war and post-cold-war eras, reflected by variable provisions of material aid. It is well recognized that understanding Afghanistan requires comprehension of the Pakistan situation as well, especially for common resources. Water is paramount because it is absolutely vital, but can be contaminated by internal or cross-border terrorism. The Kabul and Indus rivers originate in the Hindu Kush - Himalaya ranges. The Kabul River flows from Afghanistan into Pakistan, and after irrigating Peshawar basin, joins the Indus. The Indus, after its origin in Tibet and flow through the Indian Himalaya, enters Pakistan and flows south as the irrigation lifeblood of the country. Any terroristic addition of radioactive nuclides or contaminants to either river could dramatically impact the dependent riverine ecologies. Monitoring cells thus need to be established at locations in Afghanistan and Pakistan to assess base-line river variances for possible future contamination by terrorists. This paper presents a general view and the physical and chemical parameters of parts of the two rivers, and of the surrounding underground water in Peshawar Basin, including pH, conductivity, total

  8. MONITORING POTENTIAL DRUG INTERACTIONS AND REACTIONS VIA NETWORK ANALYSIS OF INSTAGRAM USER TIMELINES.

    Science.gov (United States)

    Correia, Rion Brattig; Li, Lang; Rocha, Luis M

    2016-01-01

    Much recent research aims to identify evidence for Drug-Drug Interactions (DDI) and Adverse Drug reactions (ADR) from the biomedical scientific literature. In addition to this "Bibliome", the universe of social media provides a very promising source of large-scale data that can help identify DDI and ADR in ways that have not been hitherto possible. Given the large number of users, analysis of social media data may be useful to identify under-reported, population-level pathology associated with DDI, thus further contributing to improvements in population health. Moreover, tapping into this data allows us to infer drug interactions with natural products-including cannabis-which constitute an array of DDI very poorly explored by biomedical research thus far. Our goal is to determine the potential of Instagram for public health monitoring and surveillance for DDI, ADR, and behavioral pathology at large. Most social media analysis focuses on Twitter and Facebook, but Instagram is an increasingly important platform, especially among teens, with unrestricted access of public posts, high availability of posts with geolocation coordinates, and images to supplement textual analysis. Using drug, symptom, and natural product dictionaries for identification of the various types of DDI and ADR evidence, we have collected close to 7000 user timelines spanning from October 2010 to June 2015.We report on 1) the development of a monitoring tool to easily observe user-level timelines associated with drug and symptom terms of interest, and 2) population-level behavior via the analysis of co-occurrence networks computed from user timelines at three different scales: monthly, weekly, and daily occurrences. Analysis of these networks further reveals 3) drug and symptom direct and indirect associations with greater support in user timelines, as well as 4) clusters of symptoms and drugs revealed by the collective behavior of the observed population. This demonstrates that Instagram

  9. A new methodology for monitoring wood fluxes in rivers using a ground camera: Potential and limits

    Science.gov (United States)

    Benacchio, Véronique; Piégay, Hervé; Buffin-Bélanger, Thomas; Vaudor, Lise

    2017-02-01

    made in terms of maximizing the potential benefit of such monitoring.

  10. Cave monitoring and the potential for palaeoclimate reconstruction from Cueva de Asiul, Cantabria (N. Spain

    Directory of Open Access Journals (Sweden)

    Andrew C. Smith

    2016-01-01

    Full Text Available Palaeoclimate records from northern Iberia are becoming increasingly sought after as this region is one of the most southerly terrestrial locations in Europe to have its climate dictated principally by the North Atlantic. Terrestrial records therefore have the potential to offer insights into changing oceanic and atmospheric circulation in the wider North Atlantic region. Cave speleothems offer one of the most promising archives from northern Iberia due to their wide geographic distribution and potential for accurately dated climate reconstruction. Cueva de Asiul, situated in Cantabria (N. Iberia; 43°19'0.63''N, 3°35'28.32''W; 285 m.a.s.l within the Matienzo karst depression is one such site that offers the potential for palaeoclimate reconstructions. Here we present three years of climate and cave monitoring from Cueva de Asiul, giving detailed insight into local meteorology, hydrology and cave ventilation dynamics. In doing so, this paper presents a background to high resolution, Holocene duration speleothem records which have been extracted from this cave. Annual average cave temperatures are +13.7ºC, with a maximum range of 1ºC, reflecting the seasonality of external air temperature (average external temp +13.8°C. Cave ventilation is controlled by changes in external air temperature and variations in external air pressure during low pressure events. Local rainfall measurements show an average of 1400 mm/year with the majority of rainfall occurring during the winter, with periods of water excess between October and April. Speleothem drip rates are characterised by summer lows and a rapid transition to higher rates at the onset of the winter season. Stable isotope analysis (δ18O, δ2H indicate that aquifer water is derived predominantly from the previous year’s rainfall and the rainfall feeding the karst system is controlled by a strong amount effect. Speleothems from this site are potentially suited to preserving extended records of

  11. WRF Model Output

    Data.gov (United States)

    U.S. Environmental Protection Agency — This dataset contains WRF model output. There are three months of data: July 2012, July 2013, and January 2013. For each month, several simulations were made: A...

  12. Governmentally amplified output volatility

    Science.gov (United States)

    Funashima, Yoshito

    2016-11-01

    Predominant government behavior is decomposed by frequency into several periodic components: updating cycles of infrastructure, Kuznets cycles, fiscal policy over business cycles, and election cycles. Little is known, however, about the theoretical impact of such cyclical behavior in public finance on output fluctuations. Based on a standard neoclassical growth model, this study intends to examine the frequency at which public investment cycles are relevant to output fluctuations. We find an inverted U-shaped relationship between output volatility and length of cycle in public investment. This implies that periodic behavior in public investment at a certain frequency range can cause aggravated output resonance. Moreover, we present an empirical analysis to test the theoretical implication, using the U.S. data in the period from 1968 to 2015. The empirical results suggest that such resonance phenomena change from low to high frequency.

  13. CMAQ Model Output

    Data.gov (United States)

    U.S. Environmental Protection Agency — CMAQ and CMAQ-VBS model output. This dataset is not publicly accessible because: Files too large. It can be accessed through the following means: via EPA's NCC tape...

  14. VMS forms Output Tables

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — These output tables contain parsed and format validated data from the various VMS forms that are sent from any given vessel, while at sea, from the VMS devices on...

  15. Potential Application of Novel Hyperspectral LIDAR for Monitoring Crops Nitrogen Stress

    Science.gov (United States)

    Shi, Shuo; Gong, Wei; Du, Lin; Sun, Jia; Yang, Jian

    2016-06-01

    Precision agriculture has always been the research hotspot around the world. And the optimization of nitrogen fertilization for crops is the core concerns. It is not only to improve the productivity of crops but also to avoid the environmental risks caused by over-fertilization. Therefore, accurate estimation of nitrogen status is crucial for determining an nitrogen recommendation. Remote sensing techniques have been widely used to monitor crops for years, and they could offer estimations for stress status diagnosis through obtaining vertical structure parameters and spectral reflectance properties of crops. As an active remote sensing technology, lidar is particularly attractive for 3-dimensional information at a high point density. It has unique edges in obtaining vertical structure parameters of crops. However, capability of spectral reflectance properties is what the current lidar technology lacks because of single wavelength detection. To solve this problem, the concept of novel hyperspectral lidar (HSL), which combines the advantages of hyperspectal reflectance with high 3-dimensional capability of lidar, was proposed in our study. The design of instrument was described in detail. A broadband laser pulse was emitted and reflectance spectrum with 32 channels could be detected. Furthermore, the experiment was carried out by the novel HSL system to testify the potential application for monitoring nitrogen stress. Rice under different levels of nitrogen fertilization in central China were selected as the object of study, and four levels of nitrogen fertilization (N1-N4) were divided. With the detection of novel lidar system, high precision structure parameters of crops could be provided. Meanwhile, spectral reflectance properties in 32 wavebands were also obtained. The high precision structure parameters could be used to evaluate the stress status of crops. And abundant spectral information in 32 wavebands could improve the capacity of lidar system significantly

  16. LOAD THAT MAXIMIZES POWER OUTPUT IN COUNTERMOVEMENT JUMP

    Directory of Open Access Journals (Sweden)

    Pedro Jimenez-Reyes

    2016-02-01

    Full Text Available ABSTRACT Introduction: One of the main problems faced by strength and conditioning coaches is the issue of how to objectively quantify and monitor the actual training load undertaken by athletes in order to maximize performance. It is well known that performance of explosive sports activities is largely determined by mechanical power. Objective: This study analysed the height at which maximal power output is generated and the corresponding load with which is achieved in a group of male-trained track and field athletes in the test of countermovement jump (CMJ with extra loads (CMJEL. Methods: Fifty national level male athletes in sprinting and jumping performed a CMJ test with increasing loads up to a height of 16 cm. The relative load that maximized the mechanical power output (Pmax was determined using a force platform and lineal encoder synchronization and estimating the power by peak power, average power and flight time in CMJ. Results: The load at which the power output no longer existed was at a height of 19.9 ± 2.35, referring to a 99.1 ± 1% of the maximum power output. The load that maximizes power output in all cases has been the load with which an athlete jump a height of approximately 20 cm. Conclusion: These results highlight the importance of considering the height achieved in CMJ with extra load instead of power because maximum power is always attained with the same height. We advise for the preferential use of the height achieved in CMJEL test, since it seems to be a valid indicative of an individual's actual neuromuscular potential providing a valid information for coaches and trainers when assessing the performance status of our athletes and to quantify and monitor training loads, measuring only the height of the jump in the exercise of CMJEL.

  17. Wait, treat and see: echocardiographic monitoring of brain-dead potential donors with stunned heart

    Directory of Open Access Journals (Sweden)

    Casartelli Marilena

    2012-06-01

    Full Text Available Abstract Background Heart transplantation is limited by a severe donor organ shortage. Potential donors with brain death (BD and left ventricular dysfunction due to neurogenic stunning are currently excluded from donation – although such abnormalities can be reversible with aggressive treatment including Hormonal Treatment (HT and deferred organ retrieval. Aim To assess the recovery of left ventricular dysfunction in potential brain-dead donors with hemodynamic instability treated by aggressive treatment and HT. Methods In a single-center, observational study design, we evaluated 15 consecutive brain-dead potential donors (DBD (8 males, age = 48 ± 15 years with hemodynamic instability. All underwent standard hemodynamic monitoring and transthoracic 2-dimensional echo (2-DE with assessment of Ejection Fraction (EF. Measurements were obtained before BD and after BD within 6 h, at 24 h and within 48 h. HT (with insulin, methylprednisolone, vasopressin and T3 was started as soon as possible to treat hemodynamic instability and avoid administration of norepinephrine (NE. Eligible potential heart donors underwent coronary angiography. Results After HT, we observed a normalization of hemodynamic conditions with improvement of mean arterial pressure (pre = 68 ± 8 mmHg vs post = 83 ± 13 mmHg, p 2 vs post 3.7 ± 1.2 L/min/m2, p , coronary artery stenosis was present in 2 of the 10 consented donors. Eight hearts were uneventfully transplanted. No early graft failure occurred and all eight recipients were alive at 6-month follow-up. Conclusion In BD donors, intensive treatment including HT is associated with improvement of regional and global LV function and reverse remodeling detectable by transthoracic 2DE. Donor hearts with recovered LV function may be eligible for uneventful heart transplant. The wait (in brain death, treat (with HT and see (with 2D echo strategy can help rescue organs suitable for

  18. Self-potential and Complex Conductivity Monitoring of In Situ Hydrocarbon Remediation in Microbial Fuel Cell

    Science.gov (United States)

    Zhang, C.; Revil, A.; Ren, Z.; Karaoulis, M.; Mendonca, C. A.

    2013-12-01

    Petroleum hydrocarbon contamination of soil and groundwater in both non-aqueous phase liquid and dissolved forms generated from spills and leaks is a wide spread environmental issue. Traditional cleanup of hydrocarbon contamination in soils and ground water using physical, chemical, and biological remedial techniques is often expensive and ineffective. Recent studies show that the microbial fuel cell (MFC) can simultaneously enhance biodegradation of hydrocarbons in soil and groundwater and yield electricity. Non-invasive geophysical techniques such as self-potential (SP) and complex conductivity (induced polarization) have shown the potential to detect and characterize the nature of electron transport mechanism of in situ bioremediation of organic contamination plumes. In this study, we deployed both SP and complex conductivity in lab scale MFCs to monitor time-laps geophysical response of degradation of hydrocarbons by MFC. Two different sizes of MFC reactors were used in this study (DI=15 cm cylinder reactor and 94.5cm x 43.5 cm rectangle reactor), and the initial hydrocarbon concentration is 15 g diesel/kg soil. SP and complex conductivity measurements were measured using non-polarizing Ag/AgCl electrodes. Sensitivity study was also performed using COMSOL Multiphysics to test different electrode configurations. The SP measurements showed stronger anomalies adjacent to the MFC than locations afar, and both real and imaginary parts of complex conductivity are greater in areas close to MFC than areas further away and control samples without MFC. The joint use of SP and complex conductivity could in situ evaluate the dynamic changes of electrochemical parameters during this bioremediation process at spatiotemporal scales unachievable with traditional sampling methods. The joint inversion of these two methods to evaluate the efficiency of MFC enhanced hydrocarbon remediation in the subsurface.

  19. A Vectorial Capacity Product to Monitor Changing Malaria Transmission Potential in Epidemic Regions of Africa

    Directory of Open Access Journals (Sweden)

    Pietro Ceccato

    2012-01-01

    Full Text Available Rainfall and temperature are two of the major factors triggering malaria epidemics in warm semi-arid (desert-fringe and high altitude (highland-fringe epidemic risk areas. The ability of the mosquitoes to transmit Plasmodium spp. is dependent upon a series of biological features generally referred to as vectorial capacity. In this study, the vectorial capacity model (VCAP was expanded to include the influence of rainfall and temperature variables on malaria transmission potential. Data from two remote sensing products were used to monitor rainfall and temperature and were integrated into the VCAP model. The expanded model was tested in Eritrea and Madagascar to check the viability of the approach. The analysis of VCAP in relation to rainfall, temperature and malaria incidence data in these regions shows that the expanded VCAP correctly tracks the risk of malaria both in regions where rainfall is the limiting factor and in regions where temperature is the limiting factor. The VCAP maps are currently offered as an experimental resource for testing within Malaria Early Warning applications in epidemic prone regions of sub-Saharan Africa. User feedback is currently being collected in preparation for further evaluation and refinement of the VCAP model.

  20. "Evolution Canyon," a potential microscale monitor of global warming across life.

    Science.gov (United States)

    Nevo, Eviatar

    2012-02-21

    Climatic change and stress is a major driving force of evolution. The effects of climate change on living organisms have been shown primarily on regional and global scales. Here I propose the "Evolution Canyon" (EC) microscale model as a potential life monitor of global warming in Israel and the rest of the world. The EC model reveals evolution in action at a microscale involving biodiversity divergence, adaptation, and incipient sympatric speciation across life from viruses and bacteria through fungi, plants, and animals. The EC consists of two abutting slopes separated, on average, by 200 m. The tropical, xeric, savannoid, "African" south-facing slope (AS = SFS) abuts the forested "European" north-facing slope (ES = NFS). The AS receives 200-800% higher solar radiation than the ES. The ES represents the south European forested maquis. The AS and ES exhibit drought and shade stress, respectively. Major adaptations on the AS are because of solar radiation, heat, and drought, whereas those on the ES relate to light stress and photosynthesis. Preliminary evidence suggests the extinction of some European species on the ES and AS. In Drosophila, a 10-fold higher migration was recorded in 2003 from the AS to ES. I advance some predictions that could be followed in diverse species in EC. The EC microclimatic model is optimal to track global warming at a microscale across life from viruses and bacteria to mammals in Israel, and in additional ECs across the planet.

  1. Potential of UAVs for Monitoring Mudflat Morphodynamics (Application to the Seine Estuary, France

    Directory of Open Access Journals (Sweden)

    Marion Jaud

    2016-04-01

    Full Text Available Intertidal mudflats play a critical role in estuarine exchange, connecting marine and continental supplies of nutrients and sediments. However, their complex morphodynamics, associated with a wide range of physical and biological processes, are still poorly understood and require further field investigation. In addition, mudflats are challenging areas for Structure-from-Motion (SfM photogrammetric surveys. Indeed, the mudflats generally hold back residual tidal water, which can make stereo restitution particularly difficult because of poor correlations or sun-glint effects. This study aims to show the potential of light UAVs (Unmanned Aerial Vehicles for monitoring sedimentary hydrodynamics at different spatial scales in a silty estuary. For each UAV mission an orthophotograph and a Digital Elevation Model (DEM are computed. From repeated surveys the diachronic evolution of the area can be observed via DEM differencing. Considering the ground texture in such a context, the stereo restitution process is made possible because of the high spatial resolution of the UAV photographs. Providing a synoptic view as well as high spatial resolution (less than 4 cm, the UAV dataset enables multi-scale approaches from the study of large areas to the morphodynamics of smaller-scale sedimentary structures and the morphodynamics impact of plant ground cover.

  2. Monitoring the Effects of Acupoint Antioxidant Intervention by Measuring Electrical Potential Difference along the Meridian

    Directory of Open Access Journals (Sweden)

    Ming-Ming Xu

    2015-01-01

    Full Text Available Previous studies suggest that superoxide anions are possibly traveling along acupuncture meridians. The electrical potential difference (EPD between acupoints may be related to the movement. To test the above hypothesis, we conducted a study investigating the effects of acupoint antioxidant interventions on the meridian EPD. Firstly, ST39 (L and ST44 (L were screened out for the EPD detection along the stomach meridian, and ST36 (L was selected for interventions including acumassage with the control cream, as well as the TAT-SOD cream for 30 minutes, or injection with reduced glutathione sodium. The EPD between ST39 and ST44 was recorded for 80 minutes and measured again 48 h later. While the EPD increased during the acumassage, the acumassage with TAT-SOD cream and the glutathione injection generated waves of EPD increased, indicating the migration or removal from the visceral organ of a greater quantity of superoxide. Remarkably lower EPD readings 48 h later with both antioxidant acupoint interventions than the mere acumassage imply a more complete superoxide flushing out due to the restored superoxide pathway at the acupoint after interventions. The results confirm superoxide transportation along the meridians and demonstrate a possibility of acupoint EPD measurement as a tool to monitor changes in the meridians and acupoints.

  3. Abnormal error monitoring in math-anxious individuals: evidence from error-related brain potentials.

    Science.gov (United States)

    Suárez-Pellicioni, Macarena; Núñez-Peña, María Isabel; Colomé, Angels

    2013-01-01

    This study used event-related brain potentials to investigate whether math anxiety is related to abnormal error monitoring processing. Seventeen high math-anxious (HMA) and seventeen low math-anxious (LMA) individuals were presented with a numerical and a classical Stroop task. Groups did not differ in terms of trait or state anxiety. We found enhanced error-related negativity (ERN) in the HMA group when subjects committed an error on the numerical Stroop task, but not on the classical Stroop task. Groups did not differ in terms of the correct-related negativity component (CRN), the error positivity component (Pe), classical behavioral measures or post-error measures. The amplitude of the ERN was negatively related to participants' math anxiety scores, showing a more negative amplitude as the score increased. Moreover, using standardized low resolution electromagnetic tomography (sLORETA) we found greater activation of the insula in errors on a numerical task as compared to errors in a non-numerical task only for the HMA group. The results were interpreted according to the motivational significance theory of the ERN.

  4. Abnormal error monitoring in math-anxious individuals: evidence from error-related brain potentials.

    Directory of Open Access Journals (Sweden)

    Macarena Suárez-Pellicioni

    Full Text Available This study used event-related brain potentials to investigate whether math anxiety is related to abnormal error monitoring processing. Seventeen high math-anxious (HMA and seventeen low math-anxious (LMA individuals were presented with a numerical and a classical Stroop task. Groups did not differ in terms of trait or state anxiety. We found enhanced error-related negativity (ERN in the HMA group when subjects committed an error on the numerical Stroop task, but not on the classical Stroop task. Groups did not differ in terms of the correct-related negativity component (CRN, the error positivity component (Pe, classical behavioral measures or post-error measures. The amplitude of the ERN was negatively related to participants' math anxiety scores, showing a more negative amplitude as the score increased. Moreover, using standardized low resolution electromagnetic tomography (sLORETA we found greater activation of the insula in errors on a numerical task as compared to errors in a non-numerical task only for the HMA group. The results were interpreted according to the motivational significance theory of the ERN.

  5. Hydrogel-forming microneedle arrays: Potential for use in minimally-invasive lithium monitoring.

    Science.gov (United States)

    Eltayib, Eyman; Brady, Aaron J; Caffarel-Salvador, Ester; Gonzalez-Vazquez, Patricia; Zaid Alkilani, Ahlam; McCarthy, Helen O; McElnay, James C; Donnelly, Ryan F

    2016-05-01

    We describe, for the first time, hydrogel-forming microneedle (s) (MN) arrays for minimally-invasive extraction and quantification of lithium in vitro and in vivo. MN arrays, prepared from aqueous blends of hydrolysed poly(methyl-vinylether-co-maleic anhydride) and crosslinked by poly(ethyleneglycol), imbibed interstitial fluid (ISF) upon skin insertion. Such MN were always removed intact. In vitro, mean detected lithium concentrations showed no significant difference following 30min MN application to excised neonatal porcine skin for lithium citrate concentrations of 0.9 and 2mmol/l. However, after 1h application, the mean lithium concentrations extracted were significantly different, being appropriately concentration-dependent. In vivo, rats were orally dosed with lithium citrate equivalent to 15mg/kg and 30mg/kg lithium carbonate, respectively. MN arrays were applied 1h after dosing and removed 1h later. The two groups, having received different doses, showed no significant difference between lithium concentrations in serum or MN. However, the higher dosed rats demonstrated a lithium concentration extracted from MN arrays equivalent to a mean increase of 22.5% compared to rats which received the lower dose. Hydrogel-forming MN clearly have potential as a minimally-invasive tool for lithium monitoring in outpatient settings. We will now focus on correlation between serum and MN lithium concentrations.

  6. Beliefs about the Potential Impacts of Exploiting Non-Timber Forest Products Predict Voluntary Participation in Monitoring

    Science.gov (United States)

    Dantas Brites, Alice; Morsello, Carla

    2017-06-01

    Harvesting and trading non-timber forest products is advocated as a win-win strategy for conservation and development, yet it can produce negative ecological and socioeconomic impacts. Hence, monitoring exploitation outcomes is essential, and participatory monitoring has been suggested to be the most suitable approach. Among possible approaches, participatory monitoring is preferred because it is likely to increase people's awareness and beliefs regarding impacts or potential impacts, thus inducing behavioral changes, although the evidence in this regard is contradictory. We therefore evaluated whether people's beliefs about the potential ecological and socioeconomic impacts of non-timber forest product exploitation increased their likelihood of volunteering to monitor. We studied a community of forest inhabitants in the Brazilian Amazon who harvested and traded a commercially important non-timber forest product. Two methods of data gathering were employed: (i) a survey of 166 adults (51 households) to evaluate people's beliefs and their stated intention to engage in four different monitoring tasks and (ii) four pilot monitoring tasks to evaluate who actually participated. Based on mixed-effects regressions, the results indicated that beliefs regarding both types of impacts could predict participation in certain tasks, although gender, age and schooling were occasionally stronger predictors. On average, people had stronger beliefs about potential socioeconomic impacts than about potential ecological impacts, with the former also predicting participation in ecological data gathering. This finding reinforces the importance of monitoring both types of impacts to help achieve the win-win outcomes originally proposed by non-timber forest product trade initiatives.

  7. Possibilities of using the German Federal States' permanent soil monitoring program for the monitoring of potential effects of genetically modified organisms (GMO).

    Science.gov (United States)

    Toschki, Andreas; Jänsch, Stephan; Roß-Nickoll, Martina; Römbke, Jörg; Züghart, Wiebke

    2015-01-01

    In the Directive 2001/18/EC on the deliberate release of genetically modified organisms (GMO) into the environment, a monitoring of potential risks is prescribed after their deliberate release or placing on the market. Experience and data of already existing monitoring networks should be included. The present paper summarizes the major findings of a project funded by the Federal Agency for Nature Conservation (Nutzungsmöglichkeiten der Boden-Dauerbeobachtung der Länder für das Monitoring der Umweltwirkungen gentechnisch veränderter Pflanzen. BfN Skripten, Bonn-Bad Godesberg 369, 2014). The full report in german language can be accessed on http://www.bfn.de and is available as Additional file 1. The aim of the project was to check if it is possible to use the German permanent soil monitoring program (PSM) for the monitoring of GMO. Soil organism communities are highly diverse and relevant with respect to the sustainability of soil functions. They are exposed to GMO material directly by feeding or indirectly through food chain interactions. Other impacts are possible due to their close association to soil particles. The PSM program can be considered as representative with regard to different soil types and ecoregions in Germany, but not for all habitat types relevant for soil organisms. Nevertheless, it is suitable as a basic grid for monitoring the potential effects of GMO on soil invertebrates. PSM sites should be used to derive reference values, i.e. range of abundance and presence of different relevant species of soil organisms. Based on these references, it is possible to derive threshold values to define the limit of acceptable change or impact. Therefore, a minimum set of sites and minimum set of standardized methods are needed, i.e. characterization of each site, sampling of selected soil organism groups, adequate adaptation of methods for the purpose of monitoring of potential effects of GMO. Finally, and probably most demanding, it is needed to develop

  8. Linking community-based and national REDD+ monitoring: a review of the potential

    NARCIS (Netherlands)

    Pratihast, A.K.; Herold, M.; Sy, de V.; Murdiyarso, D.; Skutsch, M.

    2013-01-01

    Countries participating in REDD+ schemes are required to establish a national monitoring system that keeps track of forest carbon changes over time. Community-based monitoring (CBM) can be useful for tracking locally driven forest change activities and their impacts. In this paper, we review some of

  9. Propofol Breath Monitoring as a Potential Tool to Improve the Prediction of Intraoperative Plasma Concentrations

    NARCIS (Netherlands)

    Colin, Pieter; Eleveld, Douglas J; van den Berg, Johannes P; Vereecke, Hugo E M; Struys, Michel M R F; Schelling, Gustav; Apfel, Christian C; Hornuss, Cyrill

    2015-01-01

    INTRODUCTION: Monitoring of drug concentrations in breathing gas is routinely being used to individualize drug dosing for the inhalation anesthetics. For intravenous anesthetics however, no decisive evidence in favor of breath concentration monitoring has been presented up until now. At the same tim

  10. Linking community-based and national REDD+ monitoring: a review of the potential

    NARCIS (Netherlands)

    Pratihast, A.K.; Herold, M.; Sy, de V.; Murdiyarso, D.; Skutsch, M.

    2013-01-01

    Countries participating in REDD+ schemes are required to establish a national monitoring system that keeps track of forest carbon changes over time. Community-based monitoring (CBM) can be useful for tracking locally driven forest change activities and their impacts. In this paper, we review some of

  11. High frequency non-invasive (HFNI bio-sensors as a potential tool for marine monitoring and assessments

    Directory of Open Access Journals (Sweden)

    Hector Andrade

    2016-10-01

    Full Text Available Marine ecosystems all over the globe are facing multiple simultaneous stressors including rapid climatic change and increased resource exploitation, such as fishing, petroleum exploration and shipping. The EU-funded DEVOTES project (DEVelopment Of innovative Tools for understanding marine biodiversity and assessing good Environmental Status aims to better understand the relationships between pressures from human activities and climatic influences and their effects on marine ecosystems. To achieve these goals, it is necessary among others, to test and validate innovative monitoring tools to improve our understanding of ecosystem and biodiversity changes. This paper outlines the application of a high frequency non-invasive (HFNI valvometer as a potential tool for long-term marine monitoring and assessments. The principle of the method is based on the regular gaping behaviour (closing and opening of the valves of bivalve molluscs and the fact that physical or chemical stressors disrupt that gaping reference pattern. Bivalve gaping behaviour is monitored in the natural environment, remotely, continuously over a time period of years, requirements that must be fulfilled if bivalve behaviour is to be a useful biomonitoring tool. Here, we review the literature and highlight potential uses of the HFNI valvometry as a biosensor, to monitor and provide early-warning alerts of changes in water quality, such as global temperature increase, releases of contaminants and toxic algal blooms. Finally, potential relevant applications for monitoring and assessing environmental status of marine waters in the context of the Marine Strategy Framework Directive are identified. Relevant descriptors, Criteria and Indicators of Good Environmental Status that might be monitored using the HFNI valvometer are discussed for monitoring bathing beaches and harbours, petroleum installations and aquaculture sites.

  12. Cardiac output measurement

    Directory of Open Access Journals (Sweden)

    Andreja Möller Petrun

    2014-02-01

    Full Text Available In recent years, developments in the measuring of cardiac output and other haemodynamic variables are focused on the so-called minimally invasive methods. The aim of these methods is to simplify the management of high-risk and haemodynamically unstable patients. Due to the need of invasive approach and the possibility of serious complications the use of pulmonary artery catheter has decreased. This article describes the methods for measuring cardiac output, which are based on volume measurement (Fick method, indicator dilution method, pulse wave analysis, Doppler effect, and electrical bioimpedance.

  13. Monitoring and Sampling Strategy for (Manufactured) Nano Objects Agglomerates and Aggregates (NOAA); Potential Added Value of the NANODEVICE Project

    NARCIS (Netherlands)

    Brouwer, D.H.; Lidén, G.; Asbach, C.; Berges, M.; Tongeren, M. van

    2014-01-01

    The production of nanomaterials and nano-enabled products is associated with the potential for workers' exposure to (manufactured) nano-objects' agglomerates and aggregates (NOAA). Workplace air monitoring studies have been conducted to assess the actual exposure; however, the methods and strategies

  14. Role of therapeutic drug monitoring in pulmonary infections : use and potential for expanded use of dried blood spot samples

    NARCIS (Netherlands)

    Hofman, Susan; Bolhuis, Mathieu S.; Koster, Remco A.; Akkerman, Onno W.; van Assen, Sander; Stove, Christophe; Alffenaar, Jan-Willem C.

    2015-01-01

    Respiratory tract infections are among the most common infections in men. We reviewed literature to document their pharmacological treatments, and the extent to which therapeutic drug monitoring (TDM) is needed during treatment. We subsequently examined potential use of dried blood spots as sample p

  15. The in vitro real-time oscillation monitoring system identifies potential entrainment factors for circadian clocks

    Directory of Open Access Journals (Sweden)

    Yasuda Akio

    2006-02-01

    Full Text Available Abstract Background Circadian rhythms are endogenous, self-sustained oscillations with approximately 24-hr rhythmicity that are manifested in various physiological and metabolic processes. The circadian organization of these processes in mammals is governed by the master oscillator within the suprachiasmatic nuclei (SCN of the hypothalamus. Recent findings revealed that circadian oscillators exist in most organs, tissues, and even in immortalized cells, and that the oscillators in peripheral tissues are likely to be coordinated by SCN, the master oscillator. Some candidates for endogenous entrainment factors have sporadically been reported, however, their details remain mainly obscure. Results We developed the in vitro real-time oscillation monitoring system (IV-ROMS by measuring the activity of luciferase coupled to the oscillatory gene promoter using photomultiplier tubes and applied this system to screen and identify factors able to influence circadian rhythmicity. Using this IV-ROMS as the primary screening of entrainment factors for circadian clocks, we identified 12 candidates as the potential entrainment factor in a total of 299 peptides and bioactive lipids. Among them, four candidates (endothelin-1, all-trans retinoic acid, 9-cis retinoic acid, and 13-cis retinoic acid have already been reported as the entrainment factors in vivo and in vitro. We demonstrated that one of the novel candidates, 15-deoxy-Δ12,14-prostaglandin J2 (15d-PGJ2, a natural ligand of the peroxisome proliferator-activated receptor-γ (PPAR-γ, triggers the rhythmic expression of endogenous clock genes in NIH3T3 cells. Furthermore, we showed that 15d-PGJ2 transiently induces Cry1, Cry2, and Rorα mRNA expressions and that 15d-PGJ2-induced entrainment signaling pathway is PPAR-γ – and MAPKs (ERK, JNK, p38MAPK-independent. Conclusion Here, we identified 15d-PGJ2 as an entrainment factor in vitro. Using our developed IV-ROMS to screen 299 compounds, we found eight

  16. Sodium Gill Potential as a Tool to Monitor Valve Closure Behavior in Freshwater Clam Corbicula fluminea in Response to Copper

    Directory of Open Access Journals (Sweden)

    Wei-Yu Chen

    2008-09-01

    Full Text Available Valve closure behavior in freshwater clam Corbicula fluminea is a biologically sensitive endpoint. The purpose of this paper was to derive an electrophysiological response model of C. fluminea to assess copper (Cu-sodium (Na interactions in gill membrane, whereby valve closure behavior and Cu toxicity could be monitored. The proposed model was based on the integration of Cu bioavailability, Na and Cu internalizations, and electrochemically-based gill potentials. Based on Na active transport under non-equilibrium conditions, predicted gill potential of -8.2 mV agreed reasonably well with published the measured transepithelial potential of -7 mV in C. fluminea. Our proposed framework captured the general features observed in model applications including: (i 50% inhibitory Cu2+ activities for Na membrane potential (ENa and uptake rate (JNa were estimated to be 0.072 and 0.043 mM, respectively, with a stoichiometry of 3Cu2+: 1ENa and 1JNa; (ii the external Cu2+-dependent internal Na concentration could be parsimoniously estimated, and (iii the site-specific clam gill potentials could be monitored. Here we provided a new approach to monitor waterborne metal toxicity to reduce the nationwide economic losses due to bans on harvesting of contaminated clam and the potential risks to the health of clams.

  17. Consenso brasileiro de monitorização e suporte hemodinâmico - parte III: métodos alternativos de monitorização do débito cardíaco e da volemia Brazilian consensus of monitoring and hemodynamic support - part III: alternative methods for cardiac output monitoring and volemia estimation

    Directory of Open Access Journals (Sweden)

    Guilherme Schettino

    2006-03-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A interpretação do débito cardíaco e da pré-carga como números absolutos não traz grandes informações sobre a hemodinâmica do paciente crítico. Em contrapartida, a monitorização da resposta do débito cardíaco à expansão volêmica ou suporte inotrópico é uma ferramenta muito útil na unidade de terapia intensiva, quando o paciente apresenta algum sinal de má perfusão tecidual. Apesar do CAP ser considerado como " padrão-ouro" na avaliação destes parâmetros, foram desenvolvidas tecnologias alternativas bastante confiáveis para a sua monitorização. MÉTODO: O processo de desenvolvimento de recomendações utilizou o método Delphi modificado para criar e quantificar o consenso entre os participantes. A AMIB determinou um coordenador para o consenso, o qual escolheu seis especialistas para comporem o comitê consultivo. Outros 18 peritos de diferentes regiões do país foram selecionados para completar o painel de 25 especialistas, médicos e enfermeiros. Um levantamento bibliográfico na MEDLINE de artigos na língua inglesa foi realizado no período de 1966 a 2004. RESULTADOS: Foram apresentadas recomendações referentes à análise da variação da pressão arterial durante ventilação mecânica, débito cardíaco contínuo por contorno de pulso arterial, débito cardíaco por diluição do lítio, Doppler transesofágico, bioimpedância transtorácica, ecocardiografia e reinalação parcial de gás carbônico. CONCLUSÕES: As novas e menos invasivas técnicas para medida do débito cardíaco, pré-carga e fluidoresponsividade apresentam adequada precisão e podem ser uma alternativa ao uso do CAP em pacientes graves.BACKGROUND AND OBJECTIVES: Cardiac output and preload as absolute data do not offer helpful information about the hemodynamic of critically ill patients. However, monitoring the response of these variables to volume challenge or inotropic drugs is a very useful tool in the

  18. Towards a more balanced view of the potentials of locally-based monitoring

    DEFF Research Database (Denmark)

    Lund, Jens Friis

    2014-01-01

    contrast to studies on co-management between States and local communities showing that such processes—in which communities and the State ostensibly work hand in hand on the monitoring and management of natural resources—are fraught with power struggles within communities as well as between communities...... the information can be perceived by those who monitor to be linked to claims over resource rights and associated benefits. In such situations, trust in locally-based monitoring should be tempered by scepticism and systems of checks and balances....

  19. Airspora concentrations in the Vaal-triangle-monitoring and potential health-effects.2, fungal spores

    CSIR Research Space (South Africa)

    Vismer, HF

    1995-08-01

    Full Text Available Atmospheric fungal spores were monitored in Vanderbijlpark for the period 1991-92 as part of the Vaal triangle air pollution health study of the medical research council and the CSIR. Cladosporium, Aspergillus/ Penicillium, Alternaria and Epicoccum...

  20. An error-related negativity potential investigation of response monitoring function in individuals with Internet addiction disorder

    Directory of Open Access Journals (Sweden)

    Zhenhe eZhou

    2013-09-01

    Full Text Available Internet addiction disorder (IAD is an impulse disorder or at least related to impulse control disorder. Deficits in executive functioning, including response monitoring, have been proposed as a hallmark feature of impulse control disorders. The error-related negativity (ERN reflects individual’s ability to monitor behavior. Since IAD belongs to a compulsive-impulsive spectrum disorder, theoretically, it should present response monitoring functional deficit characteristics of some disorders, such as substance dependence, ADHD or alcohol abuse, testing with an Erikson flanker task. Up to now, no studies on response monitoring functional deficit in IAD were reported. The purpose of the present study was to examine whether IAD displays response monitoring functional deficit characteristics in a modified Erikson flanker task.23 subjects were recruited as IAD group. 23 matched age, gender and education healthy persons were recruited as control group. All participants completed the modified Erikson flanker task while measured with event-related potentials (ERPs. IAD group made more total error rates than did controls (P < 0.01; Reactive times for total error responses in IAD group were shorter than did controls (P < 0.01. The mean ERN amplitudes of total error response conditions at frontal electrode sites and at central electrode sites of IAD group were reduced compared with control group (all P < 0.01. These results revealed that IAD displays response monitoring functional deficit characteristics and shares ERN characteristics of compulsive-impulsive spectrum disorder.

  1. PPARα-dependent increase of mouse urine output by gemfibrozil and fenofibrate.

    Science.gov (United States)

    Song, Danjun; Luo, Min; Dai, Manyun; Bu, Shizhong; Wang, Weihua; Zhang, Burong; Gonzalez, Frank J; Liu, Aiming

    2017-02-01

    While gemfibrozil and fenofibrate are prescribed for anti-dyslipidemia treatment, a rational basis for the use of these drugs for treatment of dyslipidemia with concurrent metabolic syndrome has not been established. In this study, wild-type and Pparα-null mice were fed gemfibrozil- or fenofibrate-containing diets for 14 days. Urine output (24 h) was monitored, and urine, serum, and liver and kidney tissues were subjected to toxicity assessment. A 2-month challenge followed by a 2-week wash-out was performed for gemfibrozil to determine urine output and the potential toxicity. A therapeutically equivalent dose of gemfibrozil was more effective than fenofibrate in increasing urine output. This regulatory effect was not observed in Pparα-null mice. In contrast, hepatomegaly induced by fenofibrate was more pronounced than that of gemfibrozil. No significant toxicity was observed in liver or kidney in the 2-month treatment with gemfibrozil. These data demonstrated PPARα mediates the increased urine output by fibrates. Considering the relative action on hepatomegaly and the regulatory effect on urine output, gemfibrozil may be the preferable drug to increase urine output. These results revealed a new pharmacodynamic effect of clinically prescribed PPARα agonists and suggested the potential value of gemfibrozil in modification of blood pressure.

  2. Evaluating the Potential Use of Remotely-Sensed and Model-Simulated Soil Moisture for Agricultural Drought Risk Monitoring

    Science.gov (United States)

    Yan, Hongxiang; Moradkhani, Hamid

    2016-04-01

    Current two datasets provide spatial and temporal resolution of soil moisture at large-scale: the remotely-sensed soil moisture retrievals and the model-simulated soil moisture products. Drought monitoring using remotely-sensed soil moisture is emerging, and the soil moisture simulated using land surface models (LSMs) have been used operationally to monitor agriculture drought in United States. Although these two datasets yield important drought information, their drought monitoring skill still needs further quantification. This study provides a comprehensive assessment of the potential of remotely-sensed and model-simulated soil moisture data in monitoring agricultural drought over the Columbia River Basin (CRB), Pacific Northwest. Two satellite soil moisture datasets were evaluated, the LPRM-AMSR-E (unscaled, 2002-2011) and ESA-CCI (scaled, 1979-2013). The USGS Precipitation Runoff Modeling System (PRMS) is used to simulate the soil moisture from 1979-2011. The drought monitoring skill is quantified with two indices: drought area coverage (the ability of drought detection) and drought severity (according to USDM categories). The effects of satellite sensors (active, passive), multi-satellite combined, length of climatology, climate change effect, and statistical methods are also examined in this study.

  3. Investigating the Potential Use of Environmental DNA (eDNA) for Genetic Monitoring of Marine Mammals

    DEFF Research Database (Denmark)

    Foote, Andrew David; Thomsen, P.F.; Sveegaard, Signe

    2012-01-01

    DNA for genetic monitoring we used specific primers that amplify short mitochondrial DNA sequences to detect the presence of a marine mammal, the harbor porpoise, Phocoena phocoena, in a controlled environment and in natural marine locations. The reliability of the genetic detections was investigated by comparing...

  4. The Combined Effect of Instruction and Monitor in Improving Pronunciation of Potential English Teachers

    Science.gov (United States)

    Liu, Qian; Fu, Zunwei

    2011-01-01

    The role that instruction and monitor can play in improvement of pronunciation has long been a focus of argument among linguists and researchers. It is assumed that their combination will result in positive effect. An empirical study is carried out and it is confirmed that their combination contributes greatly to the improvement of pronunciation…

  5. Performance monitoring in autism spectrum disorders : A systematic literature review of event-related potential studies

    NARCIS (Netherlands)

    Hüpen, Philippa; Groen, Yvonne; Gaastra, Geraldina F.; Tucha, Lara; Tucha, Oliver

    2016-01-01

    Autism spectrum disorder (ASD) is marked by impairments in social-emotional situations, executive functioning, and behavioral regulation. These symptoms may be related to deficits in performance monitoring, i.e., the ability to observe and evaluate one's own behavior and performance which is necessa

  6. The potential implementation of radio-frequency identification technology for personal health examination and monitoring.

    Science.gov (United States)

    Nguyen, Andrew

    2009-11-16

    This paper presents several possible applications of the radio-frequency identification (RFID) technology for personal health examination and monitoring. One application involves using RFID sensors external to the human body, while another one uses both internal and external RFID sensors. Another application involves simultaneous assessment and monitoring of many patients in a hospital setting using networks of RFID sensors. All the assessment and monitoring are done wirelessly, either continuously or periodically in any interval, in which the sensors collect information on human parts such as the lungs or heart and transmit this information to a router, PC or PDA device connected to the internet, from which patient's condition can be diagnosed and viewed by authorized medical professionals in remote locations. Instantaneous information allows medical professionals to intervene properly and in a timely fashion to prevent possible catastrophic effects to patients. The continuously assessed and monitored information provides medical professionals with more complete and long-term studies of patients. The proposed ideas promise to result in not only enhancement of the health treatment quality but also in significant reduction of medical expenditure.

  7. Monitoring and predicting shrink potential and future processing quality of potato tubers

    Science.gov (United States)

    Long-term storage of potato tubers increases risks, which are often attributed to shrink and quality loss. To minimize shrink and ensure high quality tubers, producers must closely monitor the condition of the crop during storage and make necessary adjustments to management plans. Evaluation procedu...

  8. Investigating the Potential Use of Environmental DNA (eDNA) for Genetic Monitoring of Marine Mammals

    DEFF Research Database (Denmark)

    Foote, Andrew David; Thomsen, P.F.; Sveegaard, Signe;

    2012-01-01

    DNA for genetic monitoring we used specific primers that amplify short mitochondrial DNA sequences to detect the presence of a marine mammal, the harbor porpoise, Phocoena phocoena, in a controlled environment and in natural marine locations. The reliability of the genetic detections was investigated by comparing...... detection of marine mammals....

  9. The potential for synthesizing multi-sensor remote sensing data for global volcano monitoring

    Science.gov (United States)

    Furtney, M.; Pritchard, M. E.; Carn, S. A.; McCormick, B.; Ebmeier, S. K.; Jay, J.

    2015-12-01

    Volcanoes exhibit variable eruption frequencies and styles, from near-continuous eruptions of effusive lavas to more intermittent, explosive eruptions. The monitoring frequency necessary to capture precursory signals at any volcano remains uncertain, as some warnings allot hours for evacuation. Likewise, no precursory signal appears deterministic for each volcano. Volcanic activity manifests in a variety of ways (i.e. tremor, deformation), thus requiring multiple monitoring mechanisms (i.e. geodetic, geochemical, geothermal). We are developing databases to compare relationships among remotely sensed volcanic unrest signals and eruptions. Satellite remote sensing utilizes frequent temporal measurements (daily to bi-weekly), an essential component of worldwide volcano monitoring. Remote sensing methods are also capable of detecting diverse precursory signals such as ground deformation from satellite interferometric synthetic aperture radar—InSAR— (multiple space agencies), degassing from satellite spectroscopy (i.e. OMI SO2 from NASA), and hot spots from thermal infrared (i.e. MODIS from NASA). We present preliminary results from seven SAR satellites and two thermal infrared satellites for 24 volcanoes with prominent SO2 emissions. We find near-continuous emissions at Ibu (Indonesia) since 2008 corresponded with hotspots and 10 cm of subsidence, with degassing and comparable subsidence observed at Pagan (Marianas). A newcomer to volcano monitoring, remote sensing data are only beginning to be utilized on a global scale, let alone as a synthesized dataset for monitoring developing eruptions. We foresee a searchable tool for rapidly accessing basic volcanic unrest characteristics for different types of volcanoes and whether or not they resulted in eruption. By including data from multiple satellite sensors in our database we hope to develop quantitative assessments for calculating the likelihood of eruption from individual events.

  10. Monitoring sedation for bronchoscopy in mechanically ventilated patients by using the Ramsay sedation scale versus auditory-evoked potentials

    OpenAIRE

    2014-01-01

    Background Appropriate sedation benefits patients by reducing the stress response, but it requires an appropriate method of assessment to adjust the dosage of sedatives. The aim of this study was to compare the difference in the sedation of mechanically ventilated patients undergoing flexible bronchoscopy (FB) monitored by auditory-evoked potentials (AEPs) or the Ramsay sedation scale (RSS). Methods In a prospective, randomized, controlled study, all patients who underwent FB with propofol se...

  11. REFLECTIONS ON THE INOPERABILITY INPUT-OUTPUT MODEL

    NARCIS (Netherlands)

    Dietzenbacher, Erik; Miller, Ronald E.

    2015-01-01

    We argue that the inoperability input-output model is a straightforward - albeit potentially very relevant - application of the standard input-output model. In addition, we propose two less standard input-output approaches as alternatives to take into consideration when analyzing the effects of disa

  12. Relative reliability of the auditory evoked potential and Bispectral Index for monitoring sedation level in surgical intensive care patients.

    Science.gov (United States)

    Lu, C-H; Ou-Yang, H-Y; Man, K-M; Hsiao, P-C; Ho, S-T; Wong, C-S; Liaw, W-J

    2008-07-01

    Sedation is an important adjunct therapy for patients in the intensive care unit. The objective of the present study was to observe correlation between an established subjective measure, the Ramsay Sedation Scale, and two objective tools for monitoring critically ill patients: the Bispectral Index (BIS) and auditory evoked potential. Ninety patients undergoing major surgery scheduled for postoperative mechanical ventilation and continuous sedation with propofol and fentanyl were selected. Electrodes for determining BIS and auditory evoked potential were placed on the foreheads of all patients according to manufacturer's specifications at least six hours after patients' arrival at the intensive care unit. Ramsay Sedation Scale, BIS, signal quality index, composite A-line autoregressive index (AAI) and electromyographic activities were recorded every five minutes for 30 minutes. BIS and AAI showed good correlation amongst readings (r(s)=0.697, P Ramsay Sedation Scale (BIS, tau=-0.689; AAI, tau=-0.621; P Ramsay Sedation Scale. However, the BIS and auditory evoked potential monitors do not perform adequately as a substitute in the assessment of sedated intensive care unit patients. These monitors could be used as part of an integrated approach for the evaluation of those patients especially when the subjective scales do not work well in the setting of neuromuscular blockade or may not be sufficiently sensitive to evaluate very deep sedation.

  13. Comparison of visual evoked potentials elicited by light-emitting diodes and TV monitor stimulation in patients with multiple sclerosis and potentially related conditions.

    Science.gov (United States)

    Andersson, T; Sidén, A

    1994-11-01

    Visual evoked potentials elicited by reversal of a checkerboard pattern constructed of square, red light-emitting diodes (LEDs) were compared with a conventional black and white pattern displayed on a TV monitor in control subjects and in 71 patients with established or suspected multiple sclerosis. Both stimuli elicited distinct responses in the control groups: the latencies were longer with LED stimulation while the amplitudes of the various components were differently altered. The frequency of abnormal responses among the patients was higher with LED stimulation than with TV stimulation, but the highest diagnostic yield was obtained when both methods were combined.

  14. Exploring the Potential of TanDEM-X Data in Rice Monitoring

    Science.gov (United States)

    Erten, E.

    2015-12-01

    In this work, phenological parameters such as growth stage, calendar estimation, crop density and yield estimation for rice fields are estimated employing TanDEM-X data. Currently, crop monitoring is country-dependent. Most countries have databases based on cadastral information and annual farmer inputs. Inaccuracies are coming from wrong or missing farmer declarations and/or coarsely updated cadastral boundary definitions. This leads to inefficient regulation of the market, frauds as well as to ecological risks. An accurate crop calendar is also missing, since farmers provide estimations in advance and there is no efficient way to know the growth status over large plantations. SAR data is of particular interest for these purposes. The proposed method includes two step approach including field detection and phenological state estimation. In the context of precise farming it is substantial to define field borders which are usually changing every cultivation period. Linking the SAR inherit properties to transplanting practice such as irrigation, the spatial database of rice-planted agricultural crops can be updated. Boundaries of agricultural fields will be defined in the database, and assignments of crops and sowing dates will be continuously updated by our monitoring system considering that sowing practice variously changes depending on the field owner decision. To define and segment rice crops, the system will make use of the fact that rice fields are characterized as flooded parcels separated by path networks composed by soil or rare grass. This natural segmentation is well detectable by inspecting low amplitude and coherence values of bistatic acquisitions. Once the field borders are defined, the phenology estimation of crops monitored at any time is the key point of monitoring. In this aspect the wavelength and the polarization option of TanDEM-X are enough to characterize the small phenological changes. The combination of bistatic interferometry and Radiative

  15. Field and Laboratory Evaluation of the Potential for Monitored Natural Attenuation of Perchlorate in Groundwater

    Science.gov (United States)

    2007-07-01

    9. DoD – Department of Defense 10. DOC – Dissolved Organic Carbon 11. EOD – Explosive Ordnance Disposal 12. EOS® - Emulsified Oil Substrate 13...500 mg/L emulsified soybean oil, as an additional positive control. Microcosms were incubated at room temperature and monitored at regular...constructed with 10-feet of 4-inch diameter Sch. 40 PVC well screen (.020 slotted) and the intermediate depth wells were constructed 30 with 15 feet of

  16. Automated monitoring: a potential solution for achieving sustainable improvement in hand hygiene practices.

    Science.gov (United States)

    Levchenko, Alexander I; Boscart, Veronique M; Fernie, Geoff R

    2014-08-01

    Adequate hand hygiene is often considered as the most effective method of reducing the rates of hospital-acquired infections, which are one of the major causes of increased cost, morbidity, and mortality in healthcare. Electronic monitoring technologies provide a promising direction for achieving sustainable hand hygiene improvement by introducing the elements of automated feedback and creating the possibility to automatically collect individual hand hygiene performance data. The results of the multiphase testing of an automated hand hygiene reminding and monitoring system installed in a complex continuing care setting are presented. The study included a baseline Phase 1, with the system performing automated data collection only, a preintervention Phase 2 with hand hygiene status indicator enabled, two intervention Phases 3 and 4 with the system generating hand hygiene reminding signals and periodic performance feedback sessions provided, and a postintervention Phase 5 with only hand hygiene status indicator enabled and no feedback sessions provided. A significant increase in hand hygiene performance observed during the first intervention Phase 3 was sustained over the second intervention Phase 4, with the postintervention phase also indicating higher hand hygiene activity rates compared with the preintervention and baseline phases. The overall trends observed during the multiphase testing, the factors affecting acceptability of the automated hand hygiene monitoring system, and various strategies of technology deployment are discussed.

  17. A review of potential methods of determining critical effect size for designing environmental monitoring programs.

    Science.gov (United States)

    Munkittrick, Kelly R; Arens, Collin J; Lowell, Richard B; Kaminski, Greg P

    2009-07-01

    The effective design of field studies requires that sample size requirements be estimated for important endpoints before conducting assessments. This a priori calculation of sample size requires initial estimates for the variability of the endpoints of interest, decisions regarding significance levels and the power desired, and identification of an effect size to be detected. Although many programs have called for use of critical effect sizes (CES) in the design of monitoring programs, few attempts have been made to define them. This paper reviews approaches that have been or could be used to set specific CES. The ideal method for setting CES would be to define the level of protection that prevents ecologically relevant impacts and to set a warning level of change that would be more sensitive than that CES level to provide a margin of safety; however, few examples of this approach being applied exist. Program-specific CES could be developed through the use of numbers based on regulatory or detection limits, a number defined through stakeholder negotiation, estimates of the ranges of reference data, or calculation from the distribution of data using frequency plots or multivariate techniques. The CES that have been defined often are consistent with a CES of approximately 25%, or two standard deviations, for many biological or ecological monitoring endpoints, and this value appears to be reasonable for use in a wide variety of monitoring programs and with a wide variety of endpoints.

  18. An event-related potential investigation of error monitoring in adults with a history of psychosis.

    Science.gov (United States)

    Chan, Chi C; Trachik, Benjamin J; Bedwell, Jeffrey S

    2015-09-01

    Previous research suggests that deficits in error monitoring contribute to psychosis and poor functioning. Consistent with the NIMH Research Domain Criteria initiative, this study examined electrophysiological brain activity, appraisal of self-performance, and personality traits related to psychosis during error monitoring in individuals with and without a history of psychosis across disorders. Error-related negativity (ERN), correct response negativity (CRN), error positivity (Pe), and correct response positivity (Pc) were recorded in 14 individuals with a history of psychosis (PSY) and 12 individuals with no history of psychosis (CTR) during a flanker task. Participants continuously rated their performance and completed the Schizotypal Personality Questionnaire-Brief Revised (SPQ-BR). Compared with CTR, PSY exhibited reduced ERN and Pe amplitudes and was also less accurate at evaluating their performance. Group differences were specific to error trials. Across all participants, smaller Pe amplitudes were associated with greater scores on the SPQ-BR Cognitive-Perceptual factor and less accuracy in subjective identification of errors. Individuals with a history of psychosis, regardless of diagnosis, demonstrated abnormal neural activity and imprecise confidence in response during error monitoring. Results suggest that disruptions in neural circuitry may underlie specific clinical symptoms across diagnostic categories. Copyright © 2014 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

  19. Challenges in Ecohydrological Monitoring at Soil-Vegetation Interfaces: Exploiting the Potential for Fibre Optic Technologies

    Science.gov (United States)

    Chalari, A.; Ciocca, F.; Krause, S.; Hannah, D. M.; Blaen, P.; Coleman, T. I.; Mondanos, M.

    2015-12-01

    The Birmingham Institute of Forestry Research (BIFoR) is using Free-Air Carbon Enrichment (FACE) experiments to quantify the long-term impact and resilience of forests into rising atmospheric CO2 concentrations. The FACE campaign critically relies on a successful monitoring and understanding of the large variety of ecohydrological processes occurring across many interfaces, from deep soil to above the tree canopy. At the land-atmosphere interface, soil moisture and temperature are key variables to determine the heat and water exchanges, crucial to the vegetation dynamics as well as to groundwater recharge. Traditional solutions for monitoring soil moisture and temperature such as remote techniques and point sensors show limitations in fast acquisition rates and spatial coverage, respectively. Hence, spatial patterns and temporal dynamics of heat and water fluxes at this interface can only be monitored to a certain degree, limiting deeper knowledge in dynamically evolving systems (e.g. in impact of growing vegetation). Fibre optics Distributed Temperature Sensors (DTS) can measure soil temperatures at high spatiotemporal resolutions and accuracy, along kilometers of optical cable buried in the soil. Heat pulse methods applied to electrical elements embedded in the optical cable can be used to obtain the soil moisture. In July 2015 a monitoring system based on DTS has been installed in a recently forested hillslope at BIFoR in order to quantify high-resolution spatial patterns and high-frequency temporal dynamics of soil heat fluxes and soil moisture conditions. Therefore, 1500m of optical cables have been carefully deployed in three overlapped loops at 0.05m, 0.25m and 0.4m from the soil surface and an electrical system to send heat pulses along the optical cable has been developed. This paper discussed both, installation and design details along with first results of the soil moisture and temperature monitoring carried out since July 2015. Moreover, interpretations

  20. Monitoring Disinfection Byproduct Forming Potential with Simultaneous Absorbance Spectra and Fluorescence Excitation-Emission Mapping: Supporting Stage 2 EPA Regulation Monitoring Compliance

    Science.gov (United States)

    Gilmore, A. M.

    2011-12-01

    Water treatment plants in the United States will soon (by 2013 to 2013) be required to initialize enhanced monitoring for reducing disinfection by-products (DBPs) to meet the Stage 2 levels enforced by the EPA. The key to successfully meeting these requirements lies in the treatment plant's ability to deal with often dramatic source-water variations in natural organic matter (NOM) content. Whereas the regulated levels of NOM must be determined by measuring total organic carbon (TOC) often this parameter does not provide rapid or cost-effective qualitative or quantitative assessment of the various humic, fulvic and other aromatic NOM components. However, 2 main optical techniques namely UV absorbance and fluorescence excitation-emission mapping can be used for rapid assessment with precise identification of humic and fulvic components. This study presents data from a new type of instrument which simultaneously measures the UV-VIS absorbance spectrum and EEM. The rapid absorbance-EEM is facilitated by a single system that is more than 100 time faster than conventional scanning absorbance and fluoresence optical benches. The new system can continuously collect EEMs and absorbance spectra at a rate often greater than 1 per min with the extra capacity to monitor the UV254 absorbance and fluorescence emission spectrum excited at 254 nm in 4 ms intervals (an equivalent scan rate of 5.5 million nm/min). The EEM spectral data is corrected for all instrumental response factors including concentration dependent inner-filter effects. The accumulated EEM data sets can be modeled using conventional peak identification, PARAFAC and or PCA analysis of the fractionated samples to predict the trihalomethane forming potential (THMFP). This study compares the effectiveness of THFMP predictive models based on these three techniques and explains how these can be readily employed to facilitate the Stage 2 regulation compliance for DBP monitoring.

  1. Post-discharge electrocardiogram Holter monitoring in recently hospitalised individuals with chronic atrial fibrillation to enhance therapeutic monitoring and identify potentially predictive phenotypes.

    Science.gov (United States)

    Ball, Jocasta; Carrington, Melinda J; Thompson, David R; Horowitz, John D; Stewart, Simon

    2015-10-01

    Atrial fibrillation (AF) is the most common cardiac arrhythmia managed in clinical practice. Maintenance of intended rate or rhythm control following hospitalisation is a key therapeutic goal. The purpose of this study was to assess post-discharge maintenance of intended AF control and classify potentially predictive heart rate (HR) phenotypes via electrocardiogram (ECG) Holter monitoring. In a sub-study of a multicentre randomised controlled trial comparing AF-specific management with usual care, 24-hour ECG Holter monitoring was undertaken in 133 patients 7-14 days post-discharge. Intended rate and rhythm control were compared to Holter data. Analysis of the frequency distribution of mean hour-to-hour differences identified those with labile HRs. Mean age was 71 ± 10 years, 67 (50%) were male and mean HR was 72 ± 14 bpm. Most (89%) had persistent AF (median time in AF=39% (IQR 0-100%)). Uncontrolled HR (>90 bpm for >10% of recording) occurred in 35 (26%) patients and 49 (37%) patients did not achieve their intended rate (n=26) or rhythm control (n=23). Patients in the upper quartile of mean hour-to-hour HR variability were identified as persistently labile (n=33). A further group (n=22) with periodically labile HRs was identified. Those with coronary artery disease (OR 0.34; 95% CI 0.13-0.91, p=0.033) or renal disease/dysfunction (OR 0.24; 95% CI 0.06-0.98, p=0.047) were less likely to demonstrate HR stability (n=78). Post-discharge ECG Holter monitoring of AF patients represents a valuable tool to identify deviations in intended rhythm/rate control and adjust therapeutic management accordingly. It may also identify individuals who demonstrate labile HRs. © The European Society of Cardiology 2014.

  2. An Analysis of Potential Stream Fish and Fish Habitat Monitoring Procedures for the Inland Northwest: Annual Report 1999.

    Energy Technology Data Exchange (ETDEWEB)

    Peterson, James T.; Wollrab, Sherry P.

    1999-09-01

    Recent concerns over the rapid declines of native stream-fish populations in the inland Northwest have prompted the USDA Forest Service to institute interim land management practices intended to stop further declines in fish habitat quality and protect existing high quality habitat. Natural resource managers in the Inland Northwest need tools for assessing the success or failure of conservation policies and the impacts of management actions on fish and fish habitats. Effectiveness monitoring is one such potential tool, but there are currently no established monitoring protocols. Since 1991, US Forest Service biologists have used the standardized R1/R4 inventory procedures to measure fish and fish habitats on agency lands throughout the Intermountain West. The widespread use and acceptance of these standardized procedures and the large amount of data collected suggest that the R1/R4 procedures might provide the basis for an effectiveness monitoring protocol. Using fish and fish habitat data collected by Forest Service biologists, the authors assessed the efficiency of the R1/R4 procedures for monitoring stream fish and fish habitats.

  3. Motivation and semantic context affect brain error-monitoring activity: an event-related brain potentials study.

    Science.gov (United States)

    Ganushchak, Lesya Y; Schiller, Niels O

    2008-01-01

    During speech production, we continuously monitor what we say. In situations in which speech errors potentially have more severe consequences, e.g. during a public presentation, our verbal self-monitoring system may pay special attention to prevent errors than in situations in which speech errors are more acceptable, such as a casual conversation. In an event-related potential study, we investigated whether or not motivation affected participants' performance using a picture naming task in a semantic blocking paradigm. Semantic context of to-be-named pictures was manipulated; blocks were semantically related (e.g., cat, dog, horse, etc.) or semantically unrelated (e.g., cat, table, flute, etc.). Motivation was manipulated independently by monetary reward. The motivation manipulation did not affect error rate during picture naming. However, the high-motivation condition yielded increased amplitude and latency values of the error-related negativity (ERN) compared to the low-motivation condition, presumably indicating higher monitoring activity. Furthermore, participants showed semantic interference effects in reaction times and error rates. The ERN amplitude was also larger during semantically related than unrelated blocks, presumably indicating that semantic relatedness induces more conflict between possible verbal responses.

  4. Deficits in error-monitoring by college students with schizotypal traits: an event-related potential study.

    Directory of Open Access Journals (Sweden)

    Seo-Hee Kim

    Full Text Available The present study used event-related potentials (ERPs to investigate deficits in error-monitoring by college students with schizotypal traits. Scores on the Schizotypal Personality Questionnaire (SPQ were used to categorize the participants into schizotypal-trait (n = 17 and normal control (n = 20 groups. The error-monitoring abilities of the participants were evaluated using the Simon task, which consists of congruent (locations of stimulus and response are the same and incongruent (locations of stimulus and response are different conditions. The schizotypal-trait group committed more errors on the Simon task and exhibited smaller error-related negativity (ERN amplitudes than did the control group. Additionally, ERN amplitude measured at FCz was negatively correlated with the error rate on the Simon task in the schizotypal-trait group but not in the control group. The two groups did not differ in terms of correct-related potentials (CRN, error positivity (Pe and correct-related positivity (Pc amplitudes. The present results indicate that individuals with schizotypal traits have deficits in error-monitoring and that reduced ERN amplitudes may represent a biological marker of schizophrenia.

  5. The potentials of the third generation of flow injection analysis for nutrient monitoring and fractionation analysis

    DEFF Research Database (Denmark)

    Miró, Manuel; Hansen, Elo Harald; Buanuam, Janya

    2006-01-01

    In the present communication, the third generation of flow injection analysis, the so-called micro sequential-injection Laboratory-on-Valve (μSI-LOV), is presented as a miniaturized, automated approach for on-line monitoring of nutrients in different environmental compartments as effected under...... enclosed and strictly controlled conditions. Special emphasis is placed on coupling μSI-LOV on-line with a recently developed microcolumn to perform dynamic fractionation schemes for ascertaining the availability of phosphorous forms in solid substrates for biota uptake under simulated environmental...

  6. Highly Sensitive Measurement of Bio-Electric Potentials by Boron-Doped Diamond (BDD) Electrodes for Plant Monitoring.

    Science.gov (United States)

    Ochiai, Tsuyoshi; Tago, Shoko; Hayashi, Mio; Fujishima, Akira

    2015-10-23

    We describe a sensitive plant monitoring system by the detection of the bioelectric potentials in plants with boron-doped diamond (BDD) electrodes. For sensor electrodes, we used commercially available BDD, Ag, and Pt plate electrodes. We tested this approach on a hybrid species in the genus Opuntia (potted) and three different trees (ground-planted) at different places in Japan. For the Opuntia, we artificially induced bioelectric potential changes by the surface potential using the fingers. We detected substantial changes in bioelectric potentials through all electrodes during finger touches on the surface of potted Opuntia hybrid plants, although the BDD electrodes were several times more sensitive to bioelectric potential change compared to the other electrodes. Similarly for ground-planted trees, we found that both BDD and Pt electrodes detected bioelectric potential change induced by changing environmental factors (temperature and humidity) for months without replacing/removing/changing electrodes, BDD electrodes were 5-10 times more sensitive in this detection than Pt electrodes. Given these results, we conclude that BDD electrodes on live plant tissue were able to consistently detect bioelectrical potential changes in plants.

  7. Site compare scripts and output

    Data.gov (United States)

    U.S. Environmental Protection Agency — Monthly site compare scripts and output used to generate the model/ob plots and statistics in the manuscript. The AQS hourly site compare output files are not...

  8. Mobile personal health records for pregnancy monitoring functionalities: Analysis and potential.

    Science.gov (United States)

    Bachiri, Mariam; Idri, Ali; Fernández-Alemán, José Luis; Toval, Ambrosio

    2016-10-01

    Personal Health Records (PHRs) are a rapidly growing area of health information technology. PHR users are able to manage their own health data and communicate with doctors in order to improve healthcare quality and efficiency. Mobile PHR (mPHR) applications for mobile devices have obtained an interesting market quota since the appearance of more powerful mobile devices. These devices allow users to gain access to applications that used to be available only for personal computers. This paper analyzes the functionalities of mobile PHRs that are specific to pregnancy monitoring. A well-known Systematic Literature Review (SLR) protocol was used in the analysis process. A questionnaire was developed for this task, based on the rigorous study of scientific literature concerning pregnancy and applications available on the market, with 9 data items and 35 quality assessments. The data items contain calendars, pregnancy information, health habits, counters, diaries, mobile features, security, backup, configuration and architectural design. A total of 33 mPHRs for pregnancy monitoring, available for iOS and Android, were selected from Apple App store and Google Play store, respectively. The results show that none of the mPHRs selected met 100% of the functionalities analyzed in this paper. The highest score achieved was 77%, while the lowest was 17%. In this paper, these features are discussed and possible paths for future development of similar applications are proposed, which may lead to a more efficient use of smartphone capabilities. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  9. A new nonlinear output tracking controller via output-feedback

    Institute of Scientific and Technical Information of China (English)

    Yun ZHANG; Yungang LIU; Yuqin DING

    2006-01-01

    In this paper, the output tracking control is investigated for a class of nonlinear systems when only output is available for feedback. Based on the multivariable analog of circle criterion, an observer is first introduced. Then, the observer-based output tracking controller is constructively designed by using the integral backstepping approach together with completing square. It is shown that, under relatively mild conditions, all the closed-loop signals are uniformly bounded.Meanwhile the system output asymptotically tracks the desired output. A simulation example is given to illustrate the effectiveness of the theoretical results.

  10. Small Drones for Community-Based Forest Monitoring: An Assessment of Their Feasibility and Potential in Tropical Areas

    Directory of Open Access Journals (Sweden)

    Jaime Paneque-Gálvez

    2014-06-01

    Full Text Available Data gathered through community-based forest monitoring (CBFM programs may be as accurate as those gathered by professional scientists, but acquired at a much lower cost and capable of providing more detailed data about the occurrence, extent and drivers of forest loss, degradation and regrowth at the community scale. In addition, CBFM enables greater survey repeatability. Therefore, CBFM should be a fundamental component of national forest monitoring systems and programs to measure, report and verify (MRV REDD+ activities. To contribute to the development of more effective approaches to CBFM, in this paper we assess: (1 the feasibility of using small, low-cost drones (i.e., remotely piloted aerial vehicles in CBFM programs; (2 their potential advantages and disadvantages for communities, partner organizations and forest data end-users; and (3 to what extent their utilization, coupled with ground surveys and local ecological knowledge, would improve tropical forest monitoring. To do so, we reviewed the existing literature regarding environmental applications of drones, including forest monitoring, and drew on our own firsthand experience flying small drones to map and monitor tropical forests and training people to operate them. We believe that the utilization of small drones can enhance CBFM and that this approach is feasible in many locations throughout the tropics if some degree of external assistance and funding is provided to communities. We suggest that the use of small drones can help tropical communities to better manage and conserve their forests whilst benefiting partner organizations, governments and forest data end-users, particularly those engaged in forestry, biodiversity conservation and climate change mitigation projects such as REDD+.

  11. Comparative Sensitivity of Intraoperative Motor Evoked Potential Monitoring in Predicting Postoperative Neurologic Deficits: Nondegenerative versus Degenerative Myelopathy.

    Science.gov (United States)

    Clark, Aaron J; Safaee, Michael; Chou, Dean; Weinstein, Philip R; Molinaro, Annette M; Clark, John P; Mummaneni, Praveen V

    2016-08-01

    Retrospective review. Intraoperative motor evoked potential (MEP) monitoring in spine surgery may assist surgeons in taking corrective measures to prevent neurologic deficits. The efficacy of monitoring MEPs intraoperatively in patients with myelopathy from nondegenerative causes has not been quantified. We compared the sensitivity and specificity of intraoperative MEP monitoring in patients with myelopathy caused by nondegenerative processes to patients with degenerative cervicothoracic spondylotic myelopathy (CSM). We retrospectively reviewed our myelopathy surgical cases during a 1-year period to identify patients with degenerative CSM and CSM of nondegenerative causes and collected data on intraoperative MEP changes and postoperative new deficits. Categorical variables were analyzed by Fisher exact test. Receiver operator curves assessed intraoperative MEP monitoring performance in the two groups. In all, 144 patients were identified: 102 had degenerative CSM and 42 had CSM of nondegenerative causes (24 extra-axial tumors, 12 infectious processes, 5 traumatic fractures, and 1 rheumatoid arthritis). For degenerative CSM, there were 11 intraoperative MEP alerts and 7 new deficits (p sensitivity was 71% and the specificity was 94%. In the nondegenerative group, there were 11 intraoperative MEP alerts and 3 deficits, which was not significant (p > 0.99). The sensitivity (33%) and specificity (74%) were lower. Among patients with degenerative CSM, the model performed well for predicting postoperative deficits (area under the curve [AUC] 0.826), which appeared better than the nondegenerative group, although it did not reach statistical significance (AUC 0.538, p = 0.16). Based on this large retrospective analysis, intraoperative MEP monitoring in surgery for nondegenerative CSM cases appears to be less sensitive to cord injury and less predictive of postoperative deficits when compared with degenerative CSM cases.

  12. Monitoring energy use of copiers to determine program design and potential savings for the Energy Star Copier program

    Energy Technology Data Exchange (ETDEWEB)

    Dandridge, C.B. [ReEnergize Consortium, Berkeley, CA (United States); Norford, L.K. [Massachussetts Institute of Technology, Cambridge, MA (United States); Nordman, B. [Lawrence Berkeley National Lab., CA (United States)

    1996-08-01

    In the past five years, considerable attention has been focused on the electricity use of office equipment in commercial office buildings. Several groups have monitored energy use of PCs, monitors, printers and fax machines. However, little attention has been paid to monitoring energy use of copiers. Procedures for testing energy usage and usage profiles of copiers are needed to make valid comparisons between machines and to determine overall energy use and potential energy savings. In this paper, the authors present a method to analyze the energy use and usage profiles of copiers. This method is determined through long-term measurements from a Watt-hour meter connected to the copier and by measuring light flashes from the copier. Energy use from the copier can also be estimated by using a test procedure developed by Dandridge. Results from using the long term monitoring methods will be presented for several different sized copiers, and compared to the estimated energy use derived from the American Society for Testing and Materials (ASTM) method. After summarizing these results, the authors determine criteria for a program to recognize energy-efficient copiers. These criteria were submitted as an Energy Star Copier program to the Environmental Protection Agency (EPA). The new Energy Star Copier Program was announced in July 1995, with criteria based on these suggestions. Using the final Energy Star Copier program criteria and this data, the authors determine potential future savings for the program. The ability to automatically turn the copier off at night is the greatest energy-saving feature most copiers can have. The best way to reduce overall office costs is to have the copier set automatically to make double-sided copies.

  13. ‘There were more wires than him’: the potential for wireless patient monitoring in neonatal intensive care

    Science.gov (United States)

    Bonner, Oliver; Beardsall, Kathryn; Crilly, Nathan; Lasenby, Joan

    2017-01-01

    Background The neonatal intensive care unit (NICU) can be one of the most stressful hospital environments. Alongside providing intensive clinical care, it is important that parents have the opportunity for regular physical contact with their babies because the neonatal period is critical for parent–child bonding. At present, monitoring technology in the NICU requires multiple wired sensors to track each baby's vital signs. This study describes the experiences that parents and nurses have with the current monitoring methods, and reports on their responses to the concept of a wireless monitoring system. Methods Semistructured interviews were conducted with six parents, each of whom had babies on the unit, and seven nurses who cared for those babies. The interviews initially focused on the participants’ experiences of the current wired system and then on their responses to the concept of a wireless system. The transcripts were analysed using a general inductive approach to identify relevant themes. Results Participants reported on physical and psychological barriers to parental care, the ways in which the current system obstructed the efficient delivery of clinical care and the perceived benefits and risks of a wireless system. The parents and nurses identified that the wires impeded baby–parent bonding; physically and psychologically. While a wireless system was viewed as potentially enabling greater interaction, staff and parents highlighted potential concerns, including the size, weight and battery life of any new device. Conclusions The many wires required to safely monitor babies within the NICU creates a negative environment for parents at a critical developmental period, in terms of physical and psychological interactions. Nurses also experience challenges with the existing system, which could negatively impact the clinical care delivery. Developing a wireless system could overcome these barriers, but there remain challenges in designing a device suitable

  14. Testing the potential of Sentinel-1 TOPS interferometry for the detection and monitoring of landslides at local scale

    Science.gov (United States)

    Fiaschi, Simone; Mantovani, Matteo; Frigerio, Simone; Marcato, Gianluca; Pasuto, Alessandro; Floris, Mario

    2016-04-01

    The recent Sentinel-1 mission, started by ESA in April 2014, provides to the scientific community new capabilities for the continuous monitoring of the Earth. In particular, the Terrain Observation by Progressive Scans (TOPS) imaging technique used in the Interferometric Wide swath (IW) acquisition mode, allow us to acquire data over very wide areas (250 km swath) at 20m spatial resolution, with 12 days revisit time, making it suitable for ground displacement monitoring applications. With more than one year of SAR images available, it is now possible to carry out monitoring activities of slow moving phenomena such as landslides at both regional and local scales. In this work, we test the potential of Sentinel-1 InSAR for the monitoring of shallow landslides occurring in a densely vegetated area in the North-Eastern Italian Pre-Alps. The test area of about 25km2, is located in the Province of Vicenza (Veneto Region, NE Italy) and is characterized by elevations up to 700m a.s.l., low slope angles, and the outcropping of volcanic deposits (lavas, pyroclastites and ignimbrites) overlaid by eluvial and colluvial deposits. The entire area is affected by a large number of different instabilities, such as shallow soil slips, flows and rotational/translational slides that mainly occur after heavy rain. The landslides are damaging the buildings and the infrastructure, in particular the road network, causing high economic loss for the Municipality. The landslides monitoring activity is performed exploiting the available Sentinel-1 SAR images using both Small Baseline Subset (SBAS) and Persistent Scatterer (PS) techniques. Furthermore, we use the same techniques to process another SAR dataset made of 22 COSMO-SkyMed (CSK) X-band images acquired over the study area in the period March 2011 - September 2012. A first comparison of the results is performed in order to assess the landslides detection capabilities of the Sentinel-1 C-band in respect to the CSK X-band. Finally, the

  15. Comparisons of Portable Sleep Monitors of Different Modalities: Potential as Naturalistic Sleep Recorders

    Directory of Open Access Journals (Sweden)

    Masahiro Matsuo

    2016-07-01

    Full Text Available Background: Humans spend more than a fourth of their life sleeping, and sleep quality has been significantly linked to health. However, the objective examination of ambulatory sleep quality remains a challenge, since sleep is a state of unconsciousness, which limits the reliability of self-reports. Therefore, a non-invasive, continuous, and objective method for the recording and analysis of naturalistic sleep is required.Objective: Portable sleep recording devices provide a suitable solution for the ambulatory analysis of sleep quality. In this study, the performance of two activity-based sleep monitors (Actiwatch and MTN-210 and a single-channel EEG-based sleep monitor (SleepScope were compared in order to examine their reliability for the assessment of sleep quality.Methods: Twenty healthy adults were recruited for this study. First, data from daily activity recorded by Actiwatch and MTN-210 were compared to determine whether MTN-210, a more affordable device, could yield data similar to Actiwatch, the de-facto standard. In addition, sleep detection ability was examined using data obtained by polysomnography as reference. One simple analysis included comparing the sleep/wake detection ability of Actiwatch, MTN-210, and SleepScope. Furthermore, the fidelity of sleep stage determination was examined using SleepScope in finer time resolution. Results: The results indicate that MTN-210 demonstrates an activity pattern comparable to that of Actiwatch, although their sensitivity preferences were not identical. Moreover, MTN-210 provides assessment of sleep duration comparable to that of the wrist-worn Actiwatch when MTN-210 was attached to the body. SleepScope featured superior overall sleep detection performance among the three methods tested. Furthermore, SleepScope was able to provide information regarding sleep architecture, although systemic bias was found. Conclusion: The present results suggest that single-channel EEG-based sleep monitors are

  16. Potential of Nassarius nitidus for monitoring organotin pollution in the lagoon of Bizerta (northern Tunisia)

    Institute of Scientific and Technical Information of China (English)

    Youssef Lahbib; Sami Abidli; Pablo Rodrfguez González; José Ignacio Garcfa Alonso; Najoua Trigui-El Menif

    2011-01-01

    Imposex and butyltin burden were assessed in Nassarius nitidus,Bolinus brandaris and Hexaplex trunculus collected at five stations in the Bizerta lagoon.Biological analysis showed that imposex followed type (a) in N.nitidus (distal evolution),against type (d) in the two muricids (proximal evolution).Imposex indices were higher in sites located nearby sources of tributyltin and N.nitidus was the least affected species of the five sites,followed by B.brandaris and H.trunculus.Butyltin analysis showed lower accumulation in N.nitidus followed by H.trunculus and B.brandaris.This study has allowed the gathering of data on imposex in a snail studied for the first time in Tunisia (N.nitidus).It suggests the possibility of using such snail as a complementary species for organotin monitoring programs in the Mediterranean and further confirmed that H.trunculus is the most suitable species for such investigations.

  17. Factors that limit the use of flash visual evoked potentials for surgical monitoring.

    Science.gov (United States)

    Cedzich, C; Schramm, J; Mengedoht, C F; Fahlbusch, R

    1988-01-01

    A study was conducted comparing the incidence with which the N2/P2/N3 was obtained after flash VEP in 3 groups: anterior visual pathway lesions, non-tumor craniotomies and non-cranial surgery. These groups allowed evaluation of the effects of anesthesia, visual pathway lesions and craniotomy on the stability of the flash VEP. It was found that the latency was not significantly affected in the 3 groups, whereas the incidence of obtainable peaks and the amplitudes were adversely affected by anesthesia, cranial surgical manipulation and especially by the presence of a visual pathway lesion. These adverse effects were so marked that the application of flash VEP for intraoperative monitoring seems of little use.

  18. Monitoring the millennium development goals: the potential role of the INDEPTH Network

    Directory of Open Access Journals (Sweden)

    Martin Bangha

    2010-09-01

    Full Text Available The Millennium Declaration, adopted by the United Nations (UN in 2000, set a series of Millennium Development Goals (MDGs as priorities for UN member countries, committing governments to realising eight major MDGs and 18 associated targets by 2015. Progress towards these goals is being assessed by tracking a series of 48 technical indicators that have since been unanimously adopted by experts. This concept paper outlines the role member Health and Demographic Surveillance Systems (HDSSs of the INDEPTH Network could play in monitoring progress towards achieving the MDGs. The unique qualities of the data generated by HDSSs lie in the fact that they provide an opportunity to measure or evaluate interventions longitudinally, through the long-term follow-up of defined populations.

  19. Tropospheric Emissions: Monitoring of Pollution (TEMPO) - Status and Potential Science Studies

    Science.gov (United States)

    Chance, Kelly

    2016-05-01

    TEMPO is the first NASA Earth Venture Instrument, to launch between 2019 and 2021. It measures atmospheric pollution from Mexico City and Cuba to the Canadian oil sands, and from the Atlantic to the Pacific, hourly at high spatial resolution, ~ 10 km2. It measures the key elements of air pollution chemistry. Geostationary (GEO) measurements capture the variability in the diurnal cycle of emissions and chemistry at sub-urban scale to improve emission inventories, monitor population exposure, and enable emission-control strategies. TEMPO measures the UV/visible spectra to retrieve O3, NO2, SO2, H2 CO, C2 H2 O2, H2 O, aerosols, cloud parameters, and UVB radiation. It tracks aerosol loading. It provides near-real-time air quality products. TEMPO is the North American component of the global geostationary constellation for pollution monitoring, with the European Sentinel-4 and the Korean GEMS. TEMPO studies may include: Solar-induced fluorescence from chlorophyll over land and in the ocean to study tropical dynamics, primary productivity, carbon uptake, to detect red tides, and to study phytoplankton; Measurements of stratospheric intrusions that cause air quality exceedances; Measurements at peaks in vehicle travel to capture the variability in emissions from mobile sources; Measurements of thunderstorm activity, including outflow regions to better quantify lightning NOx and O3 production; Cropland measurements follow the temporal evolution of emissions after fertilizer application and from rain-induced emissions from semi-arid soils; Measurements investigate the chemical processing of primary fire emissions and the secondary formation of VOCs and ozone; Measurements examine ocean halogen emissions and their impact on the oxidizing capacity of coastal environments; Spectra of nighttime lights are markers for human activity, energy conservation, and compliance with outdoor lighting standards intended to reduce light pollution.

  20. On the Potential of Surfers to Monitor Environmental Indicators in the Coastal Zone.

    Directory of Open Access Journals (Sweden)

    Robert J W Brewin

    Full Text Available The social and economic benefits of the coastal zone make it one of the most treasured environments on our planet. Yet it is vulnerable to increasing anthropogenic pressure and climate change. Coastal management aims to mitigate these pressures while augmenting the socio-economic benefits the coastal region has to offer. However, coastal management is challenged by inadequate sampling of key environmental indicators, partly due to issues relating to cost of data collection. Here, we investigate the use of recreational surfers as platforms to improve sampling coverage of environmental indicators in the coastal zone. We equipped a recreational surfer, based in the south west United Kingdom (UK, with a temperature sensor and Global Positioning System (GPS device that they used when surfing for a period of one year (85 surfing sessions. The temperature sensor was used to derive estimates of sea-surface temperature (SST, an important environmental indicator, and the GPS device used to provide sample location and to extract information on surfer performance. SST data acquired by the surfer were compared with data from an oceanographic station in the south west UK and with satellite observations. Our results demonstrate: (i high-quality SST data can be acquired by surfers using low cost sensors; and (ii GPS data can provide information on surfing performance that may help motivate data collection by surfers. Using recent estimates of the UK surfing population, and frequency of surfer participation, we speculate around 40 million measurements on environmental indicators per year could be acquired at the UK coastline by surfers. This quantity of data is likely to enhance coastal monitoring and aid UK coastal management. Considering surfing is a world-wide sport, our results have global implications and the approach could be expanded to other popular marine recreational activities for coastal monitoring of environmental indicators.

  1. Monitoring of potentially toxic cyanobacteria using an online multi-probe in drinking water sources.

    Science.gov (United States)

    Zamyadi, A; McQuaid, N; Prévost, M; Dorner, S

    2012-02-01

    Toxic cyanobacteria threaten the water quality of drinking water sources across the globe. Two such water bodies in Canada (a reservoir on the Yamaska River and a bay of Lake Champlain in Québec) were monitored using a YSI 6600 V2-4 (YSI, Yellow Springs, Ohio, USA) submersible multi-probe measuring in vivo phycocyanin (PC) and chlorophyll-a (Chl-a) fluorescence, pH, dissolved oxygen, conductivity, temperature, and turbidity in parallel. The linearity of the in vivo fluorescence PC and Chl-a probe measurements were validated in the laboratory with Microcystis aeruginosa (r(2) = 0.96 and r(2) = 0.82 respectively). Under environmental conditions, in vivo PC fluorescence was strongly correlated with extracted PC (r = 0.79) while in vivo Chl-a fluorescence had a weaker relationship with extracted Chl-a (r = 0.23). Multiple regression analysis revealed significant correlations between extracted Chl-a, extracted PC and cyanobacterial biovolume and in vivo fluorescence parameters measured by the sensors (i.e. turbidity and pH). This information will help water authorities select the in vivo parameters that are the most useful indicators for monitoring cyanobacteria. Despite highly toxic cyanobacterial bloom development 10 m from the drinking water treatment plant's (DWTP) intake on several sampling dates, low in vivo PC fluorescence, cyanobacterial biovolume, and microcystin concentrations were detected in the plant's untreated water. The reservoir's hydrodynamics appear to have prevented the transport of toxins and cells into the DWTP which would have deteriorated the water quality. The multi-probe readings and toxin analyses provided critical evidence that the DWTP's untreated water was unaffected by the toxic cyanobacterial blooms present in its source water.

  2. Assessment of Unabated Facility Emission Potentials for Evaluating Airborne Radionuclide Monitoring Requirements at Pacific Northwest National Laboratory - 2007

    Energy Technology Data Exchange (ETDEWEB)

    Ballinger, Marcel Y.; Barfuss, Brad C.; Gervais, Todd L.

    2008-01-01

    Assessments were performed to evaluate compliance with the airborne radionuclide emission monitoring requirements in the National Emission Standards for Hazardous Air Pollutants (NESHAP – U.S. Code of Federal Regulations, Title 40, Part 61, Subpart H) and Washington Administrative Code (WAC) 246-247: Radiation Protection – Air Emissions. In these NESHAP assessments, potential unabated offsite doses were evaluated for emission locations at buildings that are part of the consolidated laboratory campus of the Pacific Northwest National Laboratory. This report describes the inventory-based methods and provides the results for the NESHAP assessment performed in 2007.

  3. Assessment of Unabated Facility Emission Potentials for Evaluating Airborne Radionuclide Monitoring Requirements at Pacific Northwest National Laboratory - 2010

    Energy Technology Data Exchange (ETDEWEB)

    Ballinger, Marcel Y.; Gervais, Todd L.; Barnett, J. Matthew

    2011-05-13

    Assessments were performed to evaluate compliance with the airborne radionuclide emission monitoring requirements in the National Emission Standards for Hazardous Air Pollutants ([NESHAP]; U.S. Code of Federal Regulations, Title 40, Part 61, Subpart H) and Washington Administrative Code 246-247: Radiation Protection - Air Emissions. In these NESHAP assessments, potential unabated off-site doses were evaluated for emission locations at buildings that are part of the consolidated laboratory campus of the Pacific Northwest National Laboratory. This report describes the inventory-based methods and provides the results for the NESHAP assessment performed in 2010.

  4. On-line analysis of middle latency auditory evoked potentials (MLAEP) for monitoring depth of anaesthesia in laboratory rats

    DEFF Research Database (Denmark)

    Jensen, E W; Nygaard, M; Henneberg, S W

    1998-01-01

    using neuromuscular blocking agents (NMBA). A number of studies suggest that the Middle Latency Auditory Evoked Potentials (MLAEP) contain information about the state of consciousness in humans. The purpose of this study was to examine whether the AEP could serve as an indicator of depth of anaesthesia...... in rats. The AEP was elicited with a click stimulus and monitored in an 80 ms window synchronised to the stimulus. The AEP was extracted applying an Auto Regressive Model with Exogenous Input (ARX-model) from which a Depth of Anaesthesia Index (DAI) was calculated. DAI was normalised to 100 while awake...

  5. Cavitron ultrasonic surgical aspirator and visual evoked potential monitoring for chiasmal gliomas in children. Report of two cases.

    Science.gov (United States)

    Albright, A L; Sclabassi, R J

    1985-07-01

    The Cavitron ultrasonic surgical aspirator (CUSA) and intraoperative visual evoked potentials (VEP's) were found to be helpful in treating two children with difficult chiasmal gliomas. Approximately 60% of one tumor and 85% of the other was resected without change in the intraoperative VEP's and with no change in postoperative visual fields or acuity. The CUSA-VEP technique is useful in the infant to "buy time" for brain maturation, delaying or obviating subsequent radiotherapy. This approach may be helpful in the older child to reduce the tumor burden for subsequent chemotherapy. Chiasmal gliomas can be subtotally resected with the CUSA while visual function is monitored by intraoperative VEP's.

  6. Accurate, noninvasive detection of Helicobacter pylori DNA from stool samples: potential usefulness for monitoring treatment.

    Science.gov (United States)

    Shuber, Anthony P; Ascaño, Jennifer J; Boynton, Kevin A; Mitchell, Anastasia; Frierson, Henry F; El-Rifai, Wa'el; Powell, Steven M

    2002-01-01

    A novel DNA assay demonstrating sensitive and accurate detection of Helicobacter pylori from stool samples is reported. Moreover, in three individuals tested for therapeutic response, the assay showed the disappearance of H. pylori DNA during treatment. Thus, this noninvasive molecular biology-based assay has the potential to be a powerful diagnostic tool given its ability to specifically identify H. pylori DNA.

  7. Accurate, Noninvasive Detection of Helicobacter pylori DNA from Stool Samples: Potential Usefulness for Monitoring Treatment

    OpenAIRE

    Shuber, Anthony P; Ascaño, Jennifer J.; Boynton, Kevin A.; Mitchell, Anastasia; Frierson, Henry F.; El-Rifai, Wa’el; Powell, Steven M

    2002-01-01

    A novel DNA assay demonstrating sensitive and accurate detection of Helicobacter pylori from stool samples is reported. Moreover, in three individuals tested for therapeutic response, the assay showed the disappearance of H. pylori DNA during treatment. Thus, this noninvasive molecular biology-based assay has the potential to be a powerful diagnostic tool given its ability to specifically identify H. pylori DNA.

  8. Are flash-evoked visual potentials useful for intraoperative monitoring of visual pathway function?

    Science.gov (United States)

    Cedzich, C; Schramm, J; Fahlbusch, R

    1987-11-01

    Flash-evoked visual potentials (VEPs) recorded from the scalp were used in a series of 35 patients with tumors along the visual pathway: 3 orbital tumors, 25 perisellar tumors, 4 intraventricular tumors, and 3 occipital lesions. Preoperatively, various combinations of impaired visual fields and visual acuity were observed in over 90% of the patients. A postoperative decrease in visual function was observed in 3 cases. Of the 25 perisellar lesions, 13 were operated through a standard frontotemporal craniotomy and 12 were operated through a transnasal-transsphenoidal approach. VEPs were highly susceptible to volatile anesthetics, and there was a significant incidence of spontaneous latency increases and amplitude decreases in a large number of patients. There was an unacceptably high number of cases with significant VEP alteration occurring without concomitant visual function change. During trepanation or the transnasal approach, a reversible potential loss was observed in 11 patients, a profoundly altered wave form was seen in 8 cases, and a loss of single peaks was observed in 15 patients. During dissection of the tumor, a reversible potential loss or a potential with unidentifiable peaks was found in 25 cases; however, the VEPs recovered during closure or in the recovery room. There was no correlation between intraoperative VEP changes and the postoperative changes in visual function. In only 1 patient with an insignificant postoperative decrease in visual acuity from 0.4 to 0.3 was there a concomitant intraoperative potential loss. The major conclusion of our findings is that light-emitting diode flash-evoked VEPs demonstrate intraoperative changes that appear too early and too prominently to be caused solely by manipulation of the optic pathways.(ABSTRACT TRUNCATED AT 250 WORDS)

  9. Cardiac output during exercise

    DEFF Research Database (Denmark)

    Siebenmann, C; Rasmussen, P.; Sørensen, H.

    2015-01-01

    Several techniques assessing cardiac output (Q) during exercise are available. The extent to which the measurements obtained from each respective technique compares to one another, however, is unclear. We quantified Q simultaneously using four methods: the Fick method with blood obtained from...... the right atrium (Q(Fick-M)), Innocor (inert gas rebreathing; Q(Inn)), Physioflow (impedance cardiography; Q(Phys)), and Nexfin (pulse contour analysis; Q(Pulse)) in 12 male subjects during incremental cycling exercise to exhaustion in normoxia and hypoxia (FiO2  = 12%). While all four methods reported...... a progressive increase in Q with exercise intensity, the slopes of the Q/oxygen uptake (VO2) relationship differed by up to 50% between methods in both normoxia [4.9 ± 0.3, 3.9 ± 0.2, 6.0 ± 0.4, 4.8 ± 0.2 L/min per L/min (mean ± SE) for Q(Fick-M), Q(Inn), QP hys and Q(Pulse), respectively; P = 0...

  10. In Field Monitoring of Potential Detrimental Effects of Biofuels Production on Soil Quality

    Science.gov (United States)

    Wielopolski, L.; Torbert, A.

    2008-12-01

    Soil organic carbon (SOC) content is recognized as a soil quality indicator that is susceptible to degradation with tillage and with biomass removal from the soil surface. In addition to the reported benefits of leaving crop residue on the soil surface of reducing soil erosion, providing plant nutrients and reducing water losses in runoff events, biomass harvesting for energy production can negatively impact SOC. Reported values of SOC accumulation under conservation tillage systems varied widely from below zero to upwards of 1300 kg/ha/yr depending on the crop type and mean annual temperature. However, very few studies have been conducted with of no-tillage practices with concurrent management of crop residue removal. A negative impact on SOC balance has been reported with extensive biomass removal from cropping systems, but this also is dependent on mean temperature and rainfall amounts. Perennial grasses are strong candidates as a source for biofuel production. These, in turn, will entail very large monoculture fields' with no soil disturbance and extensive harvesting of residues. These conditions may degrade the soil condition by depleting soil's nutrients beyond the point of standard fertilization and reduce the SOC. Thus raising the question of sustainability and, more importantly, challenging the fundamental assertion that the entire cycle of energy production from biofuels, on balance, will reduce the levels of atmospheric carbon dioxide. To monitor soil conditions over vast areas with variable landscapes using current state-of-the-art procedures for soil sampling and analysis by dry combustion presents a formidable task that is labor intensive and time consuming. We propose to implement a new instrument for soil carbon, nitrogen and potassium monitoring in soil that is non-destructive and can be used in either stationary or continuous scanning modes of operation. The instrument senses the elements to an approximate depth of 30 cm and provides true mean

  11. Near-infrared spectroscopy (NIRS) of epilithic material in streams has a potential for monitoring impact from mining.

    Science.gov (United States)

    Persson, Jan; Nilsson, Mats; Bigler, Christian; Brooks, Stephen J; Renberg, Ingemar

    2007-04-15

    There is an increasing demand for cost-effective methods for environmental monitoring, and here we assess the potential of near-infrared spectroscopy (NIRS) on epilithic material from streams (material covering submerged stones) as a new method for monitoring the impact of pollution from mining and mining-related industries. NIRS, a routine technique in industry, registers the chemical properties of organic material on a molecular level and can detect minute alterations in the composition of epilithic material. Epilithic samples from 65 stream sites (42 uncontaminated and 23 contaminated) in northern Sweden were analyzed. The NIRS approach was evaluated by comparing it with the results of chemical analyses and diatom analyses of the same samples. Based on Principal Component Analysis, the NIRS data distinguished contaminated from uncontaminated sites and performed slightly betterthan chemical analyses and clearly betterthan diatom analyses. Of the streams designated a priori as contaminated, 74% were identified as contaminated by NIRS, 65% were identified by chemical analysis, and 26% were identified by diatom analysis. Unlike chemical analyses of water samples, NIRS data reflect biological impacts in the streams, and the epilithic material integrates impact over time. Given that, and the simplicity of NIRS-analyses, further studies to assess the use of NIRS of epilithic material as an inexpensive environmental monitoring method are justified.

  12. An experimental study of postoperative monitoring for innervated free muscle graft by the compound muscle action potential in rabbits.

    Science.gov (United States)

    Tan, Soo-Heong; Shigetomi, Mitsunori; Doi, Kazuteru

    2012-07-01

    This experiment establishes the principles of using the compound muscle action potential (CMAP) as a possible postoperative monitor for free muscle grafts. Twenty rabbits were divided into two groups of ten each to investigate the effects of ischemia on CMAP of the muscles. Rectus femoris model was used and contralateral muscle was used as control. In all muscles total normothermic ischemia of 1.5 hours to mimic the time needed for transfer and inset of the flap was followed by occlusion of the artery in one group and vein in another group after 3 hours. During this ischemia of 1 hour, the CMAP amplitudes decreased and the latencies were prolonged. Latency prolongation was detected within 10 minutes of total, arterial, or venous ischemia. During the revascularization, both amplitude and latency improved, but not to the original values at the start. The results show that CMAP monitoring can provide easily detectable, objective indication of vascular compromise to a muscle graft within as early as 10 minutes of total, arterial, and venous ischemia. Changes in latency are more constant and predictable compared with amplitude changes. This method can provide continuous monitoring and can be used in buried muscle grafts.

  13. Monitoring the Dynamics of Water Flow at a High-Mountain Permafrost Site Using Electrical Self-Potential Measurements

    Science.gov (United States)

    Kemna, A.; Weigand, M.; Wagner, F.; Hilbich, C.; Hauck, C.

    2016-12-01

    Flow of (liquid) water plays a crucial role in the dynamics of coupled thermo-hydro-mechanical processes in terrestrial permafrost systems. To better understand these processes in the active layer of permafrost regions, with the ultimate goal of adequately incorporating them in numerical models for improved scenario prediction, monitoring approaches offering high spatial and temporal resolution, areal coverage, and especially sensitivity to subsurface water flow, are highly desired. This particularly holds for high-mountain slopes, where strong variability in topography, precipitation, and snow cover, along with significant subsurface soil/rock heterogeneity, gives rise to complex spatio-temporal patterns of water flow during seasonal thawing and freezing periods. The electrical self-potential (SP) method is well known to, in theory, meeting the above monitoring demands by measuring the electrical streaming potential which is generated at the microscopic scale when water flows along electrically non-neutral interfaces. Despite its inherent sensitivity to subsurface water flow, the SP method has not yet been used for the monitoring of high-mountain permafrost sites. We here present first results from an SP monitoring survey conducted at the Schilthorn (2970 m asl) in the Bernese Alps, Switzerland, where SP data have been collected since September 2013 at a sampling rate of 10 min on a permanently installed array of 12 non-polarizing electrodes covering an area of 35 m by 15 m. While the SP time series exhibit systematic daily variations, with part of the signal clearly correlated with temperature, in particular in the snow-free periods, the largest temporal changes in the SP signal occur in spring, when the snow cover melts and thawing sets on in the active layer. The period of higher temporal SP variations continues until autumn, when the signal gradually returns to relatively low variations, coinciding with the freezing of the ground. Our results suggest that the

  14. Effect of click-polarity on abnormality of intraoperatively monitored brainstem acoustic evoked potentials.

    Science.gov (United States)

    Mokrusch, T; Schramm, J; Hochstetter, A

    1988-01-01

    The configuration of brainstem acoustic evoked potentials (BAEP) is influenced by the type of click stimuli used and may thus affect detectability of abnormalities. In a group of 19 patients with lesions in the posterior fossa BAEP were recorded pre- and intraoperatively. Repeat recordings were performed in each patient in two alternating series with rarefaction and condensation click stimuli. The findings demonstrated that intraoperative potential changes in latency and amplitude were different between the two stimulation modes, but did not vary significantly in their incidence. It was also not possible to predict from the preoperative BAEP which click polarity would demonstrate intraoperative changes more markedly, taking latency and amplitude as parameters. Two conclusions are drawn from this study: None of the two stimulation modes is superior in detecting intraoperative changes and therefore no recommendation can be made which click polarity to use. When working with only one click polarity it is recommended to use occasional control recordings with the other click polarity.

  15. The Potential of Sentinel Satellites for Burnt Area Mapping and Monitoring in the Congo Basin Forests

    Directory of Open Access Journals (Sweden)

    Astrid Verhegghen

    2016-11-01

    Full Text Available In this study, the recently launched Sentinel-2 (S2 optical satellite and the active radar Sentinel-1 (S1 satellite supported by active fire data from the MODIS sensor were used to detect and monitor forest fires in the Congo Basin. In the context of a very strong El Niño event, an unprecedented outbreak of fires was observed during the first months of 2016 in open forests formations in the north of the Republic of Congo. The anomalies of the recent fires and meteorological situation compared to historical data show the severity of the drought. Burnt areas mapped by the S1 SAR and S2 Multi Spectral Instrument (MSI sensors highlight that the fires occurred mainly in Marantaceae forests, characterized by open tree canopy cover and an extensive tall herbaceous layer. The maps show that the origin of the fires correlates with accessibility to the forest, suggesting an anthropogenic origin. The combined use of the two independent and fundamentally different satellite systems of S2 and S1 captured an extent of 36,000 ha of burnt areas, with each sensor compensating for the weakness (cloud perturbations for S2, and sensitivity to ground moisture for S1 of the other.

  16. An Improved Unmixing-Based Fusion Method: Potential Application to Remote Monitoring of Inland Waters

    Directory of Open Access Journals (Sweden)

    Yulong Guo

    2015-02-01

    Full Text Available Although remote sensing technology has been widely used to monitor inland water bodies; the lack of suitable data with high spatial and spectral resolution has severely obstructed its practical development. The objective of this study is to improve the unmixing-based fusion (UBF method to produce fused images that maintain both spectral and spatial information from the original images. Images from Environmental Satellite 1 (HJ1 and Medium Resolution Imaging Spectrometer (MERIS were used in this study to validate the method. An improved UBF (IUBF algorithm is established by selecting a proper HJ1-CCD image band for each MERIS band and thereafter applying an unsupervised classification method in each sliding window. Viewing in the visual sense—the radiance and the spectrum—the results show that the improved method effectively yields images with the spatial resolution of the HJ1-CCD image and the spectrum resolution of the MERIS image. When validated using two datasets; the ERGAS index (Relative Dimensionless Global Error indicates that IUBF is more robust than UBF. Finally, the fused data were applied to evaluate the chlorophyll a concentrations (Cchla in Taihu Lake. The result shows that the Cchla map obtained by IUBF fusion captures more detailed information than that of MERIS.

  17. Long-Period seismic events at Ubinas Volcano (Peru): their implications and potentiality as monitoring tool

    Science.gov (United States)

    Zandomeneghi, D.; Inza, A.; Metaxian, J.-P.; Macedo, O.

    2012-04-01

    Ubinas volcano (Southern Peru) is an active andesitic stratovolcano, located 75 km East of Arequipa City, with an average occurrence of 6-7 eruptions per century and persistent fumarolic and phreatic activity. The most recent eruption, accompanied by explosions and by the extrusion of a lava dome, started on March 2006 with an increase of seismicity and observed fumarole occurrence followed in April by more intense explosions, recorded until May 2009. To monitor the volcanic activity, the Geophysical Institute of Peru and the Institut de Recherche pour le Développment (France), built up a seismic network around the volcano, installing 4 permanent stations and deploying 8 supplementary temporary broadband seismometers. In addition, in the period May to July 2009, a seismic experiment was carried out on the volcano flanks with 2 cross-shaped dense antennas with broadband seismometers. As the seismic activity was characterized by recurring low-frequency waveforms, we identify their pattern of occurrence through waveform cross-correlation technique, with respect to major eruptive phases and other observations (as volcano ground deformation from tiltmeters, volcanic product composition, etc). Once established their likely association with the eruptive sequence, we utilize both local network and dense-array data and analyze their location, changes in location, spectral content variations and possible physical explanation. The final aim is to introduce this kind of analysis as quantitative tool to understand ongoing eruptive phases at andesitic volcanoes and possibly to forecast magma/fluid significant movements.

  18. Potential use of produced oil sample analysis to monitor SAGD performance

    Energy Technology Data Exchange (ETDEWEB)

    Li, Z. [Society of Petroleum Engineers, Canadian Section, Calgary, AB (Canada)]|[Nexen Petroleum International, Calgary, AB (Canada); Wollen, C. [Society of Petroleum Engineers, Canadian Section, Calgary, AB (Canada)]|[OPTI-Nexen Inc., Calgary, AB (Canada); Yang, P.; Fustic, M. [Nexen Petroleum International, Calgary, AB (Canada)

    2008-10-15

    Oil viscosity and compositional gradients can affect the performance of steam injection recovery processes. In this study, reservoir simulations were conducted to investigate the effects of viscosity variation with depth on steam assisted gravity drainage (SAGD) processes and produced oil characteristics. The 2-D reservoir model consisted of a reservoir with a 40 m clean sand matrix, overtopped with interbedded shales and sand. The oil phase was comprised of 2 pseudo-components representing top and bottom bitumens. Viscosities and concentrations of the pseudo-components were calculated using linear mixing rules. Four different viscosity distribution scenarios were examined. Conceptual 3-D models were then constructed to examine the characteristics of produced oil samples in scenarios with shale barriers extending down the well directions and blocking parts of the reservoir. Results from the simulations showed that produced oil characteristics are related to the in situ profiles of reservoir flow barriers. Produced oil characteristics can be used in conjunction with oil rates, surface heave and other data to predict steam chamber development and detect the presence of baffles and barriers. The relationship between the SAGD steam chamber and variations in produced fluid characteristics were accurately characterized by the simulations. It was concluded that the approach can be used to monitor SAGD steam chamber growth. 10 refs., 1 tab., 19 figs.

  19. Latency of auditory evoked potential monitoring the effects of general anesthetics on nerve fibers and synapses

    OpenAIRE

    Bowan Huang; Feixue Liang; Lei Zhong; Minlin Lin; Juan Yang; Linqing Yan; Jinfan Xiao; Zhongju Xiao

    2015-01-01

    Auditory evoked potential (AEP) is an effective index for the effects of general anesthetics. However, it’s unknown if AEP can differentiate the effects of general anesthetics on nerve fibers and synapses. Presently, we investigated AEP latency and amplitude changes to different acoustic intensities during pentobarbital anesthesia. Latency more regularly changed than amplitude during anesthesia. AEP Latency monotonically decreased with acoustic intensity increase (i.e., latency-intensity curv...

  20. Potential Use of Salivary Markers for Longitudinal Monitoring of Inflammatory Immune Responses to Vaccination

    Directory of Open Access Journals (Sweden)

    Pei Wen Lim

    2016-01-01

    Full Text Available Vaccination, designed to trigger a protective immune response against infection, is a trigger for mild inflammatory responses. Vaccination studies can address the question of inflammation initiation, levels, and resolution as well as its regulation for respective studied pathogens. Such studies largely based on analyzing the blood components including specific antibodies and cytokines were usually constrained by number of participants and volume of collected blood sample. Hence, blood-based studies may not be able to cover the full dynamic range of inflammation responses induced by vaccination. In this review, the potential of using saliva in addition to blood for studying the kinetics of inflammatory response studies was assessed. Saliva sampling is noninvasive and has a great potential to be used for studies aimed at analysing the magnitude, time course, and variance in immune responses, including inflammation after vaccination. Based on a literature survey of inflammatory biomarkers that can be determined in saliva and an analysis of how these biomarkers could help to understand the mechanisms and dynamics of immune reactivity and inflammation, we propose that the saliva-based approach might have potential to add substantial value to clinical studies, particularly in vulnerable populations such as infants, toddlers, and ill individuals.

  1. Corrosion of Steel in Concrete – Potential Monitoring and Electrochemical Impedance Spectroscopy during Corrosion Initiation and Propagation

    DEFF Research Database (Denmark)

    Küter, Andre; Mason, Thomas O.; Geiker, Mette Rica;

    2005-01-01

    A reinforced mortar specimen that allows potential measurements and electrochemical impedance spectroscopy (EIS) immediately after preparation was designed and tested. The specimen consists of a mortar cylinder with a central rebar and a concentric arrangement of embedded Ru/Ir activated titanium...... and titanium wires can be monitored immediately after preparation. The wire arrangement also allows investigation of local changes in the bulk mortar by EIS or by measuring the potential development of the titanium wires versus an external standard electrode. The specimen design was evaluated...... in an investigation on the effect of the steel quality and the steel surface properties on initiation and propagation of chloride-induced reinforcement corrosion. Besides untreated (as received) carbon rebars and stainless rebars, selected surface treatments and galvanization were investigated. The surface treatments...

  2. The Potential for Health Monitoring in Expandable Space Modules: The Bigelow Expandable Activity Module on the ISS

    Science.gov (United States)

    Wells, Nathan D.; Madaras, Eric I.

    2017-01-01

    Expandable modules for use in space and on the Moon or Mars offer a great opportunity for volume and mass savings in future space exploration missions. This type of module can be compressed into a relatively small shape on the ground, allowing them to fit into space vehicles with a smaller cargo/fairing size than a traditional solid, metallic structure based module would allow. In April 2016, the Bigelow Expandable Activity Module (BEAM) was berthed to the International Space Station (ISS). BEAM is the first human-rated expandable habitat/module to be deployed and crewed in space. BEAM is a NASA managed ISS payload project in partnership with Bigelow Aerospace. BEAM is intended to stay attached to ISS for an operational period of 2 years to help advance the technology readiness for future expandable modules. BEAM has been instrumented with a suite of space flight certified sensors systems which will help characterize the module's performance for thermal, radiation shielding and impact monitoring against potential Micro Meteoroid/Orbital Debris (MM/OD) providing fundamental information on the BEAM environment for potential health monitoring requirements and capabilities. This paper will provide an overview of how the sensors/instrumentation systems were developed, tested, installed and an overview of the current sensor system operations. It will also discuss how the MM/OD impact detection system referred to as the Distributed Impact Detection System (DIDS) data is being processed and reviewed on the ground by the principle investigators.

  3. The Autonomous Stress Indicator for Remotely Monitoring Power System State and Watching for Potential Instability

    Directory of Open Access Journals (Sweden)

    Geza Joos

    2009-02-01

    Full Text Available The proposed Autonomous Stress Indicator (ASI is a device that monitors the contents of the protection relays on a suspect weak power system bus and generates a performance level related to the degree of system performance degradation or instability. This gives the system operators some time (minutes to take corrective action. In a given operating area there would not likely be a need for an ASI on every bus. Note that the ASI does not trip any breakers; it is an INFORMATION ONLY device. An important feature is that the system operator can subsequently interrogate the ASI to determine the factor(s that led to the performance level that has been initially annunciated, thereby leading to a course of action. This paper traces the development of the ASI which is an ongoing project. The ASI could be also described as a stress-alert device whose function is to alert the System Operator of a stressful condition at its location. The characteristics (or essential qualities of this device are autonomy, selectivity, accuracy and intelligence. These will fulfill the requirements of the recommendation of the Canada –US Task Force in the August 2003 system collapse. Preliminary tests on the IEEE 39-bus model indicate that the concept has merit and development work is in progress. While the ASI can be applied to all power system operating conditions, its principal application is to the degraded state of the system where the System Operator must act to restore the system to the secure state before it migrates to a stage of collapse. The work of ASI actually begins with the Areas of Vulnerability and ends with the Predictive Module as described in detail in this paper. An application example of a degraded system using the IEEE 39-bus system is included.

  4. Basic problems and new potentials in monitoring sediment transport using Japanese pipe type geophone

    Science.gov (United States)

    Sakajo, Saiichi

    2016-04-01

    The authors have conducted a lot of series of monitoring of sediment transport by pipe type geophone in a model hydrological channel with various gradients and water discharge, using the various size of particles from 2 to 21 mm in the diameter. In the case of casting soils particle by particle into the water channel, 1,000 test cases were conducted. In the case of casting all soils at a breath into the water channel, 100 test cases were conducted. The all test results were totally analyzed by the conventional method, with visible judgement by video pictures. Then several important basic problems were found in estimating the volume and particle distributions by the conventional method, which was not found in the past similar studies. It was because the past studies did not consider the types of collisions between sediment particle and pipe. Based on these experiments, the authors have firstly implemented this idea into the old formula to estimate the amount of sediment transport. In the formula, two factors of 1) the rate of sensing in a single collision and 2) the rate of collided particles to a cast all soil particles were concretely considered. The parameters of these factors could be determined from the experimental results and it was found that the obtained formula could estimate grain size distribution. In this paper, they explain the prototype formula to estimate a set of volume and distribution of sediment transport. Another finding in this study is to propose a single collision as a river index to recognize its characteristics of sediment transport. This result could characterize the risk ranking of sediment transport in the rivers and mudflow in the mountainous rivers. Furthermore, in this paper the authors explain how the preciseness of the pipe geophone to sense the smaller sediment particles shall be improved, which has never been able to be sensed.

  5. A low-cost electronic tensiometer system for continuous monitoring of soil water potential

    Directory of Open Access Journals (Sweden)

    Martin Thalheimer

    2013-12-01

    Full Text Available A low cost system for measuring soil water potential and data logging was developed on the basis of an Arduino microcontroller board, electronic pressure transducers and water-filled tensiometers. The assembly of this system requires only minimal soldering, limited to the wiring of the power supply and the pressure sensors to the microcontroller board. The system presented here is, therefore, not only inexpensive, but also suited for easy reproduction by users with only basic technical skills. The utility and reliability of the system was tested in a commercial apple orchard.

  6. Orbital monitoring of the Brazilian pasturelands: patterns, trends and potential ecosystem services

    Science.gov (United States)

    Ferreira, L. G.; Parente, L. L.; Arantes, A. E.; Araujo, F. M.; Brito, J. S.; Nogueira, S.; Faria, A. S.; Santos, A.; Ferreira, M. E.; Silva, J. R.; Rufino, L., Jr.; Vieira, P.; Silva, W. C.; Stefani, F.; Veloso, G.; Nogueira, L.; Aguado, O. O.

    2015-12-01

    In Brazil, where cultivated pastures constitute the dominant land use form, cattle ranching intensification plays a major role towards more environmentally sustainable agricultural practices, through its potential for mitigating GHG emissions, as well as by making available cost-effective land reserve for other uses. However, environmentally sustainable livestock intensification, one of the key goals pursued by Plano ABC (the federal government low carbon agriculture plan), strongly depends on our ability to more precisely identify pasture conditions, improvement needs, and the respective cattle support capacities. To this end, and with the support of the Gordon and Betty Moore Foundation, we have concentrated efforts in order to have: 1) a more detailed and updated map of the brazilian pasturelands; 2) a thorough biophysical differentiation of these pastures according to degradation stages / forage levels; and 3) an estimation of overall pasture productivity trends. Our initial estimates, based on the interpretation of satellite and census data, suggest that as much as 50% of the total grazing area in Brazil (about 170 Mhectares) are moderately or severely affected by soil-plant degradation. On the other hand, our preliminary results also corroborate the enormous potential of well managed pastures to positively impact carbon and water fluxes. Based on satellite data and pasture samples from large and productive cattle ranch operations in the central savanna biome in Brazil (Cerrado), we estimated total growing season (October to April) biomass and evapotranspiration to correspond to 9 Gt of carbon and 420 Gt of water, respectively.

  7. An optofluidic constriction chip for monitoring metastatic potential and drug response of cancer cells.

    Science.gov (United States)

    Martinez Vazquez, R; Nava, G; Veglione, M; Yang, T; Bragheri, F; Minzioni, P; Bianchi, E; Di Tano, M; Chiodi, I; Osellame, R; Mondello, C; Cristiani, I

    2015-04-01

    Cellular mechanical properties constitute good markers to characterize tumor cells, to study cell population heterogeneity and to highlight the effect of drug treatments. In this work, we describe the fabrication and validation of an integrated optofluidic chip capable of analyzing cellular deformability on the basis of the pressure gradient needed to push a cell through a narrow constriction. We demonstrate the ability of the chip to discriminate between tumorigenic and metastatic breast cancer cells (MCF7 and MDA-MB231) and between human melanoma cells with different metastatic potential (A375P and A375MC2). Moreover, we show that this chip allows highlighting the effect of drugs interfering with microtubule organization (paclitaxel, combretastatin A-4 and nocodazole) on cancer cells, which leads to changes in the pressure-gradient required to push cells through the constriction. Our single-cell microfluidic device for mechanical evaluation is compact and easy to use, allowing for an extensive use in different laboratory environments.

  8. Event-related potential evidence of accessing gender stereotypes to aid source monitoring.

    Science.gov (United States)

    Leynes, P Andrew; Crawford, Jarret T; Radebaugh, Anne M; Taranto, Elizabeth

    2013-01-23

    Source memory for the speaker's voice (male or female) was investigated when semantic knowledge (gender stereotypes) could and could not inform the episodic source judgment while event-related potentials (ERPs) were recorded. Source accuracy was greater and response times were faster when stereotypes could predict the speaker's voice at test. Recollection supported source judgments in both conditions as indicated by significant parietal "old/new" ERP effects (500-800ms). Prototypical late ERP effects (the right frontal "old/new" effect and the late posterior negativity, LPN) were evident when source judgment was based solely on episodic memory. However, these two late ERP effects were diminished and a novel, frontal-negative ERP with left-central topography was observed when stereotypes aided source judgments. This pattern of ERP activity likely reflects activation of left frontal or left temporal lobes when semantic knowledge, in the form of a gender stereotype, is accessed to inform the episodic source judgment.

  9. Potential for integrated optical circuits in advanced aircraft with fiber optic control and monitoring systems

    Science.gov (United States)

    Baumbick, Robert

    1991-01-01

    The current Fiber Optic Control System Integration (FOCSI) program is reviewed and the potential role of IOCs in FOCSI applications is described. The program is intended for building, environmentally testing, and demonstrating operation in piggyback flight tests (no active control with optical sensors) of a representative sensor system for propulsion and flight control. The optical sensor systems are to be designed to fit alongside the bill-of-materials sensors for comparison. The sensors are to be connected to electrooptic architecture cards which will contain the optical sources and detectors to recover and process the modulated optical signals. The FOCSI program is to collect data on the behavior of passive optical sensor systems in a flight environment and provide valuable information on installation amd maintenance problems for this technology, as well as component survivability (light sources, connectors, optical fibers, etc.).

  10. Serial Input Output

    Energy Technology Data Exchange (ETDEWEB)

    Waite, Anthony; /SLAC

    2011-09-07

    Serial Input/Output (SIO) is designed to be a long term storage format of a sophistication somewhere between simple ASCII files and the techniques provided by inter alia Objectivity and Root. The former tend to be low density, information lossy (floating point numbers lose precision) and inflexible. The latter require abstract descriptions of the data with all that that implies in terms of extra complexity. The basic building blocks of SIO are streams, records and blocks. Streams provide the connections between the program and files. The user can define an arbitrary list of streams as required. A given stream must be opened for either reading or writing. SIO does not support read/write streams. If a stream is closed during the execution of a program, it can be reopened in either read or write mode to the same or a different file. Records represent a coherent grouping of data. Records consist of a collection of blocks (see next paragraph). The user can define a variety of records (headers, events, error logs, etc.) and request that any of them be written to any stream. When SIO reads a file, it first decodes the record name and if that record has been defined and unpacking has been requested for it, SIO proceeds to unpack the blocks. Blocks are user provided objects which do the real work of reading/writing the data. The user is responsible for writing the code for these blocks and for identifying these blocks to SIO at run time. To write a collection of blocks, the user must first connect them to a record. The record can then be written to a stream as described above. Note that the same block can be connected to many different records. When SIO reads a record, it scans through the blocks written and calls the corresponding block object (if it has been defined) to decode it. Undefined blocks are skipped. Each of these categories (streams, records and blocks) have some characteristics in common. Every stream, record and block has a name with the condition that each

  11. Output Model of Steel Plant

    Institute of Scientific and Technical Information of China (English)

    ZHANG Long-qiang; TIAN Nai-yuan; ZHANG Jin; XU An-jun

    2008-01-01

    Based on the requirement of compactivity, continuity, and high efficiency, and taking full advantage of cushion capability of flexible parts such as external refining in new generation steel plant, an output model of steel plant was established in terms of matching between BOF and caster. Using this model, the BOF nominal capacity is selected, the caster output and equipment amount are computed, and then the steel plant output is computed.

  12. Nonlinear input-output systems

    Science.gov (United States)

    Hunt, L. R.; Luksic, Mladen; Su, Renjeng

    1987-01-01

    Necessary and sufficient conditions that the nonlinear system dot-x = f(x) + ug(x) and y = h(x) be locally feedback equivalent to the controllable linear system dot-xi = A xi + bv and y = C xi having linear output are found. Only the single input and single output case is considered, however, the results generalize to multi-input and multi-output systems.

  13. Inverter communications using output signal

    Energy Technology Data Exchange (ETDEWEB)

    Chapman, Patrick L.

    2017-02-07

    Technologies for communicating information from an inverter configured for the conversion of direct current (DC) power generated from an alternative source to alternating current (AC) power are disclosed. The technologies include determining information to be transmitted from the inverter over a power line cable connected to the inverter and controlling the operation of an output converter of the inverter as a function of the information to be transmitted to cause the output converter to generate an output waveform having the information modulated thereon.

  14. Potential for Monitoring Snow Cover in Boreal Forests by Combining MODIS Snow Cover and AMSR-E SWE Maps

    Science.gov (United States)

    Riggs, George A.; Hall, Dorothy K.; Foster, James L.

    2009-01-01

    Monitoring of snow cover extent and snow water equivalent (SWE) in boreal forests is important for determining the amount of potential runoff and beginning date of snowmelt. The great expanse of the boreal forest necessitates the use of satellite measurements to monitor snow cover. Snow cover in the boreal forest can be mapped with either the Moderate Resolution Imaging Spectroradiometer (MODIS) or the Advanced Microwave Scanning Radiometer for EOS (AMSR-E) microwave instrument. The extent of snow cover is estimated from the MODIS data and SWE is estimated from the AMSR-E. Environmental limitations affect both sensors in different ways to limit their ability to detect snow in some situations. Forest density, snow wetness, and snow depth are factors that limit the effectiveness of both sensors for snow detection. Cloud cover is a significant hindrance to monitoring snow cover extent Using MODIS but is not a hindrance to the use of the AMSR-E. These limitations could be mitigated by combining MODIS and AMSR-E data to allow for improved interpretation of snow cover extent and SWE on a daily basis and provide temporal continuity of snow mapping across the boreal forest regions in Canada. The purpose of this study is to investigate if temporal monitoring of snow cover using a combination of MODIS and AMSR-E data could yield a better interpretation of changing snow cover conditions. The MODIS snow mapping algorithm is based on snow detection using the Normalized Difference Snow Index (NDSI) and the Normalized Difference Vegetation Index (NDVI) to enhance snow detection in dense vegetation. (Other spectral threshold tests are also used to map snow using MODIS.) Snow cover under a forest canopy may have an effect on the NDVI thus we use the NDVI in snow detection. A MODIS snow fraction product is also generated but not used in this study. In this study the NDSI and NDVI components of the snow mapping algorithm were calculated and analyzed to determine how they changed

  15. Monitoring the fibrolytic potential of microbial ecosystems from domestic and wild ruminants browsing tanniferous forages

    Directory of Open Access Journals (Sweden)

    Nokwethemba Nqobile Philile Msimango

    2016-03-01

    Full Text Available Although the rumen microbiome has been reported to synthesize a rich source of symbiotic enzymes (exocellulase, endocellulase, hemicellulase and cellobiase, the digestion of tropical C4 grasses and browses by ruminants is still limited. Therefore, this study aimed to unveil potential fibrolytic microbial ecosystems from giraffe, kudu, impala and consortia (A1 [giraffe + kudu], A2 [giraffe + impala], A3 [kudu + impala], and A4 [giraffe + kudu + impala] browsing tanniferous plants, which can be used to improve forage utilization in domesticated goat. Crude protein enzyme extracts (CPZ from fresh faecal samples were precipitated by 60% ammonium sulphate and assayed for exocellulase, endocellulase and hemicellulase by incubating with crystalline cellulose, carboxymethyl cellulose and xylan at 38 °C with optimum pH of 5.5 to 6.5 for 1, 2, and 48 h, respectively. Enzyme specific activities were defined as μg of reducing sugar/mg CPZ. In vitro fermentation study was done by transferring 33 mL of fresh faecal inoculum into 67 mL of salivary buffer containing 1 g Acacia sieberiana and incubating for 72 h at 38 °C. Apparent degradability (APDeg, true degradability (TD, neutral detergent fibre degradability (NDFdeg, acid detergent fibre degradability (ADFdeg, microbial yield (MY, metabolizable energy (ME and total gas emitted (Gas were measured. Exocellulase activities were higher (P < 0.05 in all wild animals and consortia than those in goat except for A4. Minimal differences in hemicellulase activities (P < 0.05 were observed among goat and wild animals and consortia, while endocellulase activity was generally higher (P < 0.05 in goat than that in the rest of the systems. Apart from A3, TDeg, NDFdeg and ADFdeg were higher (P < 0.05 in all microbial ecosystems from wild animals and consortia than those in goat. Apparent degradability, MY and ME also varied (P < 0.05 among these systems. Giraffe, Kudu and A3 produced lower (P

  16. Flowpath independent monitoring of reductive dechlorination potential in a fractured rock aquifer

    Science.gov (United States)

    Bradley, P.M.; Lacombe, P.J.; Imbrigiotta, T.E.; Chapelle, F.H.; Goode, D.J.

    2009-01-01

    The flowpath dependent approaches that are typically employed to assess biodegradation of chloroethene contaminants in unconsolidated aquifers are problematic in fractured rock settings, due to difficulties defining discrete groundwater flowpaths in such systems. In this study, the variation in the potential for chloroethene biodegradation with depth was evaluated in a fractured rock aquifer using two flowpath independent lines of field evidence: (1) the presence of the three biochemical prerequisites [electron donor(s), chloroethene electron acceptor(s), and chlororespiring microorganism(s)] for efficient chloroethene chlororespiration and (2) the in situ accumulation of chloroethene reductive dechlorination daughter products. The validity of this approach was assessed by comparing field results with the results of [1, 2- 14C] cis-DCE microcosm experiments. Microcosms were prepared with depth-specific core material, which was crushed and emplaced in discrete packer intervals for 1 year to allow colonization by the indigenous microbial community. Packer intervals characterized by significant electron donor concentrations, elevated numbers of chlororespiring microorganisms, and high reductive dechlorination product to parent contaminant ratios correlated well with the production of 14C-labeled reductive dechlorination products in the microcosm experiments. These results indicate that, in the absence of information on discrete groundwater flowpaths, a modified approach emphasizing flowpath independent lines of evidence can provide insight into the temporal and spatial variability of contaminant biodegradation in fractured rock systems. ?? 2009 National Ground Water Association.

  17. Output Synchronization of Nonidentical Linear Multiagent Systems.

    Science.gov (United States)

    Wu, Yuanqing; Su, Hongye; Shi, Peng; Lu, Renquan; Wu, Zheng-Guang

    2017-01-01

    In this paper, the problem of output synchronization is investigated for the heterogeneous network with an uncertain leader. It is assumed that parameter perturbations influence the nonidentical linear agents, whose outputs are controlled to track the output of an uncertain leader. Based on the hierarchical structure of the communication graph, a novel control scheme is proposed to guarantee the output synchronization. As there exist parameter uncertainties in the models of the agents, the internal model principle is used to gain robustness versus plant parameter uncertainties. Furthermore, as the precise model of the leader is also not available, the adaptive control principle is adopted to tune the parameters in the local controllers. The developed new technique is able to simultaneously handle uncertainties in the follower parameters as well as the leader parameters. The agents in the upper layers will be treated as the exosystems of the agents in the lower layers. The local controllers are constructed in a sequential order. It is shown that the output synchronization can be achieved globally asymptotically and locally exponentially. Finally, a simulation example is given to illustrate the effectiveness and potential of the theoretic results obtained.

  18. Assessing landslide potential on coastal bluffs near Mukilteo, Washington—Geologic site characterization for hydrologic monitoring

    Science.gov (United States)

    Mirus, Benjamin B.; Smith, Joel B.; Benjamin Stark,; York Lewis,; Abigail Michel,; Baum, Rex L.

    2016-07-01

    During the summer 2015, the U.S. Geological Survey collected geologic and geotechnical data for two sites on coastal bluffs along the eastern shore of Puget Sound, Washington. The U.S. Geological Survey also installed hydrologic instrumentation at the sites and collected specimens for laboratory testing. The two sites are located on City of Mukilteo open-space land and are about 0.6 kilometers apart. The bluffs at each site are approximately 42 meters high, and rise steeply from the shoreline with 32–35° slopes. The more northerly of the two sites occupies an active landslide and is mostly unvegetated. The other site is forested, and although stable during the preparation of this report, shows evidence of historical and potential landslide activity. The slopes of the bluffs at both sites are mantled by a thin, nonuniform colluvium underlain by clay-rich glacial deposits and tills of the Whidbey Formation or Double Bluff Drift. Till consisting of sand, gravel, and cobbles caps the bluffs and rests on finer grained glacial deposits of sand, silt, and clay. These types of different glacial deposits are dense, vertically fractured, and generally have low permeability, but field observations indicate that locally the deposits are sufficiently permeable to allow lateral flow of water along fractures and subhorizontal boundaries between deposits of different texture. Laboratory tests indicate that many of the deposits are highly plastic, with low hydraulic conductivity, and moderate shear strength. Steep slopes combined with the strength and hydraulic characteristics of the deposits leave the bluffs prone to slope instability, particularly during the wet season when infiltrating rainfall changes moisture content, pore-water pressure, and effective stress within the hillslope. The instrumentation was designed to primarily observe rainfall variability and hydrologic changes in the subsurface that can affect stability of the bluffs, and also to compare the hydrologic

  19. Geochemical monitoring for potential environmental impacts of geologic sequestration of CO2

    Science.gov (United States)

    Kharaka, Yousif K.; Cole, David R.; Thordsen, James J.; Gans, Kathleen D.; Thomas, Randal B.

    2013-01-01

    Carbon dioxide sequestration is now considered an important component of the portfolio of options for reducing greenhouse gas emissions to stabilize their atmospheric levels at values that would limit global temperature increases to the target of 2 °C by the end of the century (Pacala and Socolow 2004; IPCC 2005, 2007; Benson and Cook 2005; Benson and Cole 2008; IEA 2012; Romanak et al. 2013). Increased anthropogenic emissions of CO2 have raised its atmospheric concentrations from about 280 ppmv during pre-industrial times to ~400 ppmv today, and based on several defined scenarios, CO2 concentrations are projected to increase to values as high as 1100 ppmv by 2100 (White et al. 2003; IPCC 2005, 2007; EIA 2012; Global CCS Institute 2012). An atmospheric CO2 concentration of 450 ppmv is generally the accepted level that is needed to limit global temperature increases to the target of 2 °C by the end of the century. This temperature limit likely would moderate the adverse effects related to climate change that could include sea-level rise from the melting of alpine glaciers and continental ice sheets and from the ocean warming; increased frequency and intensity of wildfires, floods, droughts, and tropical storms; and changes in the amount, timing, and distribution of rain, snow, and runoff (IPCC 2007; Sundquist et al. 2009; IEA 2012). Rising atmospheric CO2 concentrations are also increasing the amount of CO2 dissolved in ocean water lowering its pH from 8.1 to 8.0, with potentially disruptive effects on coral reefs, plankton and marine ecosystems (Adams and Caldeira 2008; Schrag 2009; Sundquist et al. 2009). Sedimentary basins in general and deep saline aquifers in particular are being investigated as possible repositories for the large volumes of anthropogenic CO2 that must be sequestered to mitigate global warming and related climate changes (Hitchon 1996; Benson and Cole 2008; Verma and Warwick 2011).

  20. ‘Cytology-on-a-Chip’ Based Sensors for Monitoring of Potentially Malignant Oral Lesions

    Science.gov (United States)

    Abram, Timothy J.; Floriano, Pierre N.; Christodoulides, Nicolaos; James, Robert; Kerr, A. Ross; Thornhill, Martin H.; Redding, Spencer W.; Vigneswaran, Nadarajah; Speight, Paul M.; Vick, Julie; Murdoch, Craig; Freeman, Christine; Hegarty, Anne M.; D’Apice, Katy; Phelan, Joan A.; Corby, Patricia M.; Khouly, Ismael; Bouquot, Jerry; Demian, Nagi M.; Weinstock, Y. Etan; Rowan, Stephanie; Yeh, Chih-Ko; McGuff, H. Stan; Miller, Frank R.; Gaur, Surabhi; Karthikeyan, Kailash; Taylor, Leander; Le, Cathy; Nguyen, Michael; Talavera, Humberto; Raja, Rameez; Wong, Jorge; McDevitt, John T.

    2016-01-01

    Despite significant advances in surgical procedures and treatment, long-term prognosis for patients with oral cancer remains poor, with survival rates among the lowest of major cancers. Better methods are desperately needed to identify potential malignancies early when treatments are more effective. Objective To develop robust classification models from cytology-on-a-chip measurements that mirror diagnostic performance of gold standard approach involving tissue biopsy. Materials and Methods Measurements were recorded from 714 prospectively recruited patients with suspicious lesions across 6 diagnostic categories (each confirmed by tissue biopsy -histopathology) using a powerful new ‘cytology-on-a-chip’ approach capable of executing high content analysis at a single cell level. Over 200 cellular features related to biomarker expression, nuclear parameters and cellular morphology were recorded per cell. By cataloging an average of 2,000 cells per patient, these efforts resulted in nearly 13 million indexed objects. Results Binary “low-risk”/“high-risk” models yielded AUC values of 0.88 and 0.84 for training and validation models, respectively, with an accompanying difference in sensitivity + specificity of 6.2%. In terms of accuracy, this model accurately predicted the correct diagnosis approximately 70% of the time, compared to the 69% initial agreement rate of the pool of expert pathologists. Key parameters identified in these models included cell circularity, Ki67 and EGFR expression, nuclear-cytoplasmic ratio, nuclear area, and cell area. Conclusions This chip-based approach yields objective data that can be leveraged for diagnosis and management of patients with PMOL as well as uncovering new molecular-level insights behind cytological differences across the OED spectrum. PMID:27531880

  1. 'Cytology-on-a-chip' based sensors for monitoring of potentially malignant oral lesions.

    Science.gov (United States)

    Abram, Timothy J; Floriano, Pierre N; Christodoulides, Nicolaos; James, Robert; Kerr, A Ross; Thornhill, Martin H; Redding, Spencer W; Vigneswaran, Nadarajah; Speight, Paul M; Vick, Julie; Murdoch, Craig; Freeman, Christine; Hegarty, Anne M; D'Apice, Katy; Phelan, Joan A; Corby, Patricia M; Khouly, Ismael; Bouquot, Jerry; Demian, Nagi M; Weinstock, Y Etan; Rowan, Stephanie; Yeh, Chih-Ko; McGuff, H Stan; Miller, Frank R; Gaur, Surabhi; Karthikeyan, Kailash; Taylor, Leander; Le, Cathy; Nguyen, Michael; Talavera, Humberto; Raja, Rameez; Wong, Jorge; McDevitt, John T

    2016-09-01

    Despite significant advances in surgical procedures and treatment, long-term prognosis for patients with oral cancer remains poor, with survival rates among the lowest of major cancers. Better methods are desperately needed to identify potential malignancies early when treatments are more effective. To develop robust classification models from cytology-on-a-chip measurements that mirror diagnostic performance of gold standard approach involving tissue biopsy. Measurements were recorded from 714 prospectively recruited patients with suspicious lesions across 6 diagnostic categories (each confirmed by tissue biopsy -histopathology) using a powerful new 'cytology-on-a-chip' approach capable of executing high content analysis at a single cell level. Over 200 cellular features related to biomarker expression, nuclear parameters and cellular morphology were recorded per cell. By cataloging an average of 2000 cells per patient, these efforts resulted in nearly 13 million indexed objects. Binary "low-risk"/"high-risk" models yielded AUC values of 0.88 and 0.84 for training and validation models, respectively, with an accompanying difference in sensitivity+specificity of 6.2%. In terms of accuracy, this model accurately predicted the correct diagnosis approximately 70% of the time, compared to the 69% initial agreement rate of the pool of expert pathologists. Key parameters identified in these models included cell circularity, Ki67 and EGFR expression, nuclear-cytoplasmic ratio, nuclear area, and cell area. This chip-based approach yields objective data that can be leveraged for diagnosis and management of patients with PMOL as well as uncovering new molecular-level insights behind cytological differences across the OED spectrum. Copyright © 2016 Elsevier Ltd. All rights reserved.

  2. Final work plan : targeted groundwater sampling and monitoring well installation for potential site reclassification at Barnes, Kansas.

    Energy Technology Data Exchange (ETDEWEB)

    LaFreniere, L. M.

    2006-07-11

    This ''Work Plan'' outlines the scope of work for a targeted groundwater sampling investigation and monitoring well installation at Barnes, Kansas. This activity is being conducted at the request of the Kansas Department of Health and Environment (KDHE), in accordance with the intergovernmental agreement between the KDHE and the Commodity Credit Corporation (CCC), an agency of the U.S. Department of Agriculture (USDA). Data resulting from the proposed work will be used to determine the hydraulic gradient near the former CCC/USDA facility, delineate the downgradient carbon tetrachloride plume, and determine additional monitoring requirements at Barnes. The overall goal is to establish criteria for monitoring leading to potential site reclassification. The proposed work will be performed on behalf of the CCC/USDA by the Environmental Science Division of Argonne National Laboratory. Argonne is a nonprofit, multidisciplinary research center operated by the University of Chicago for the U.S. Department of Energy (DOE). The Farm Service Agency of the USDA has entered into an interagency agreement with DOE, under which Argonne provides technical assistance with environmental site characterization and remediation at former CCC/USDA grain storage facilities. Argonne issued a ''Master Work Plan'' (Argonne 2002) to provide general guidance for all investigations at former CCC/USDA facilities in Kansas. The ''Master Work Plan'', approved by the KDHE, contains the materials common to investigations at all locations in Kansas. This document must be consulted for the complete details of plans for this work associated with the former CCC/USDA facility at Barnes.

  3. Evaluation of potentially nonlethal sampling methods for monitoring mercury concentrations in smallmouth bass (Micropterus dolomieu)

    Science.gov (United States)

    Schmitt, C.J.; Brumbaugh, W.G.

    2007-01-01

    We evaluated three potentially nonlethal alternatives to fillet sampling for the determination of mercury (Hg) concentrations in smallmouth bass (Micropterus dolomieu). Fish (n = 62, 226-464 mm total length) from six sites in southern Missouri were captured by electrofishing. Blood samples (1 mL) from each fish were obtained by caudal veinipuncture with a heparinized needle and syringe. Biopsy needle (10 mm x 14 gauge; three cuts per fish; 10-20 mg total dry weight) and biopsy punch (7 mm x 5 mm in diameter, one plug per fish, 30-50 mg dry weight) samples were obtained from the area beneath the dorsal fin. Fillet samples were obtained from the opposite side of the fish. All samples were freeze-dried and analyzed for total Hg by combustion amalgamation atomic absorption spectrophotometry. Mean relative standard deviations (RSDs) of triplicate samples were similar for all four methods (2.2-2.4%), but the range of RSDs was greater for blood (0.4-5.5%) than for the muscle methods (1.8-4.0%). Total Hg concentrations in muscle were 0.0200-0.8809 ??g/g wet weight; concentrations in plug, needle, and fillet samples from each fish were nearly identical. Blood Hg concentrations were 0.0006-0.0812 ??g/mL and were highly correlated with muscle concentrations; linear regressions between log-transformed blood and fillet Hg concentrations were linear and statistically significant (p explained 91-93% of the total variation. Correlations between fillet Hg concentrations and fish size and age were weak; together they explained ???37% of the total variation, and the relations differed among sites. Overall, any of the alternative methods could provide satisfactory estimates of fillet Hg in smallmouth bass; however, both blood and plug sampling with disposable instruments were easier to perform than needle sampling. The biopsy needle was the most difficult to use, especially on smaller fish, and its relative expense necessitates reuse and, consequently, thorough cleaning between fish

  4. Conflict monitoring and stimulus categorization processes involved in the prosocial attitude implicit association test: Evidence from event-related potentials.

    Science.gov (United States)

    Xiao, Fengqiu; Zheng, Zhiwei; Wang, Ya; Cui, Jifang; Chen, Yinghe

    2015-08-01

    The implicit association test (IAT) is a promising method used to assess individual implicit attitudes by indirectly measuring the strengths of associations between target and attribute categories. To date, the cognitive processes involved in the prosocial attitude IAT task have received little attention. The present study examined the temporal dynamics of the IAT that measures prosocial attitude using event-related potentials (ERPs). ERP results revealed enhanced N2 amplitudes for incongruent trials when compared with congruent trials and enhanced P300 amplitudes for congruent trials when compared with incongruent trials. In addition, the N2 amplitude differences were significantly correlated with individual prosocial behavior (the amount of donation). Our findings suggest that conflict monitoring and stimulus categorization processes are involved in the prosocial attitude IAT task and that the ERP indices of IATs that measure prosocial attitude may predict individual prosocial behavior.

  5. Measurement of the activation cross section for the (p,xn) reactions in niobium with potential applications as monitor reactions

    Energy Technology Data Exchange (ETDEWEB)

    Avila-Rodriguez, M.A. [Edmonton PET Centre, Cross Cancer Institute, Edmonton, AB, T6G 1Z2 (Canada)], E-mail: miguel.avila-rodriguez@utu.fi; Wilson, J.S. [Edmonton PET Centre, Cross Cancer Institute, Edmonton, AB, T6G 1Z2 (Canada); Schueller, M.J. [Brookhaven National Laboratory, Upton, NY 11973 (United States); McQuarrie, S.A. [Edmonton PET Centre, Cross Cancer Institute, Edmonton, AB, T6G 1Z2 (Canada)

    2008-08-15

    Excitation functions of the {sup 93}Nb(p,n){sup 93m}Mo, {sup 93}Nb(p,pn){sup 92m}Nb and {sup 93}Nb(p,{alpha}n){sup 89}Zr nuclear reactions were measured up to 17.4 MeV by the conventional activation method using the stacked-foil technique. Stacks were irradiated at different incident energies on the TR19/9 cyclotron at the Edmonton PET Centre. The potential of the measured excitation functions for use as monitor reactions was evaluated and tested by measuring activity ratios at a different facility. Single Nb foils were irradiated at incident energies in the range from 12 to 19 MeV on the TR19/9 cyclotron at Brookhaven National Laboratory. Results are compared with the published data and with theoretical values as determined by the nuclear reaction model code EMPIRE.

  6. Collector-Output Analysis Program

    Science.gov (United States)

    Glandorf, D. R.; Phillips, Robert F., II

    1986-01-01

    Collector-Output Analysis Program (COAP) programmer's aid for analyzing output produced by UNIVAC collector (MAP processor). COAP developed to aid in design of segmentation structures for programs with large memory requirements and numerous elements but of value in understanding relationships among components of any program. Crossreference indexes and supplemental information produced. COAP written in FORTRAN 77.

  7. Monitoring potential ecological impacts of a utility-scale photovoltaic panel facility on a creosote-bursage plant community

    Science.gov (United States)

    Apodaca, L.; Devitt, D. A.

    2016-12-01

    High energy demands and greater financial viability have propelled recent growth in the solar energy market. Southern Nevada is poised to become a major contributor of green energy through the commissioning of public and private lands for solar development, but there exists a pressing need to better understand the ecological consequences of these facilities as documentation of the impacts of large-scale solar operations on surrounding environments is severely lacking. The Copper Mountain 2 (CM2) solar facility in Eldorado Valley, Nevada, USA utilizes nearly 1.8 square kilometers of photovoltaic panels to generate enough energy to power about 50,000 homes and is situated within a predominately creosote (Larrea tridentata) and white bursage (Ambrosia dumosa) habitat. Currently, the potential impacts on the local environment related to this massive development are being studied from two perspectives: microclimate effects and alteration of surface hydrology. A series of meteorological towers and ibuttons are being used to monitor microclimate changes in the area of CM2 and the adjacent natural habitat as localized climate within the facility may be altering growing conditions in nearby desert plant communities. Because the placement of CM2 represents a major obstacle to established surface water flow, a transect of soil moisture probe access tubes have been placed in association with creosote plants along a downslope gradient from the facility to observe changes to soil water storage. Individual creosote and bursage plant physiologies are also being monitored to study any potential increase in plant stress influenced by the CM2 solar facility. Most measurements have been ongoing for at least one year. Greater details on the research infrastructure will be presented along with the latest observational data.

  8. Advancing the Potential of Citizen Science for Urban Water Quality Monitoring: Exploring Research Design and Methodology in New York City

    Science.gov (United States)

    Hsueh, D.; Farnham, D. J.; Gibson, R.; McGillis, W. R.; Culligan, P. J.; Cooper, C.; Larson, L.; Mailloux, B. J.; Buchanan, R.; Borus, N.; Zain, N.; Eddowes, D.; Butkiewicz, L.; Loiselle, S. A.

    2015-12-01

    Citizen Science is a fast-growing ecological research tool with proven potential to rapidly produce large datasets. While the fields of astronomy and ornithology demonstrate particularly successful histories of enlisting the public in conducting scientific work, citizen science applications to the field of hydrology have been relatively underutilized. We demonstrate the potential of citizen science for monitoring water quality, particularly in the impervious, urban environment of New York City (NYC) where pollution via stormwater runoff is a leading source of waterway contamination. Through partnerships with HSBC, Earthwatch, and the NYC Water Trail Association, we have trained two citizen science communities to monitor the quality of NYC waterways, testing for a suite of water quality parameters including pH, turbidity, phosphate, nitrate, and Enterococci (an indicator bacteria for the presence of harmful pathogens associated with fecal pollution). We continue to enhance these citizen science programs with two additions to our methodology. First, we designed and produced at-home incubation ovens for Enterococci analysis, and second, we are developing automated photo-imaging for nitrate and phosphate concentrations. These improvements make our work more publicly accessible while maintaining scientific accuracy. We also initiated a volunteer survey assessing the motivations for participation among our citizen scientists. These three endeavors will inform future applications of citizen science for urban hydrological research. Ultimately, the spatiotemporally-rich dataset of waterway quality produced from our citizen science efforts will help advise NYC policy makers about the impacts of green infrastructure and other types of government-led efforts to clean up NYC waterways.

  9. Identification and monitoring of potentially dangerous glacial lakes in northern Tien Shan (Kazakhstan/Kyrgyzstan) using geoinformation techniques

    Science.gov (United States)

    Bolch, Tobias; Pradhan, Biswajeet; Peters, Juliane; Buchroithner, Manfred

    2010-05-01

    Like in many other parts of the world, the glaciers in northern Tien Shan are receding and the permafrost is thawing and concomitant glacial lakes are developing. Outbursts of these glacial lakes pose severe hazards for the society. Over the last decade, several outbursts in this seismically active region are documented. Multi-temporal space imageries are an ideal means to study and monitor glaciers and glacial lakes over larger areas. Morphometric analyses and modelling approaches allow the estimation of the potential danger of glacial lake outburst floods (GLOFs). In this paper, we present a comprehensive approach to identify glaciers and the potentially dangerous glacial lakes based on multi-temporal space imagery from 1972 (Corona KH-4B), 1973 (Landsat MSS), 1991 (Landsat TM), 1999 (Landsat ETM+), 2000/2001/ (ASTER) 2005, and 2008 (Landsat TM) as well as morphometric analysis and modelling. The identification and monitoring of glacial lakes were carried out automatically using image ratioing and the Normalized Difference Water Index (except for the panchromatic Corona images). The results were evaluated and, if necessary, manually edited. The probability of the growth of a glacial lake was estimated by analysing glacier changes, glacier motion, and slope analysis. A permafrost model based on morphometric parameters, solar radiation and regionalised temperature conditions aided us to asses the effect of probable permafrost thawing. A GIS-based model was applied in order to simulate the possible downstream impact of a lake outburst. The findings of our studies indicate a continuous glacier recession with an increasing number and area of glacial lakes. This possibly leads into a higher risk of a glacial lake outburst. Finally, the lakes are classified according to their outburst probability and their downstream impact.

  10. Monitoring and modelling of pumping-induced self-potentials for transmissivity estimation within a heterogeneous confined aquifer

    Science.gov (United States)

    DesRoches, Aaron J.; Butler, Karl E.

    2016-12-01

    Variations in self-potentials (SP) measured at surface during pumping of a heterogeneous confined fractured rock aquifer have been monitored and modelled in order to investigate capabilities and limitations of SP methods in estimating aquifer hydraulic properties. SP variations were recorded around a pumping well using an irregular grid of 31 non-polarizing Pb-PbCl2 that were referenced to a remote electrode and connected to a commercial multiplexer and digitizer/data logger through a passive lowpass filter on each channel. The lowpass filter reduced noise by a factor of 10 compared to levels obtained using the data logger's integration-based sampling method for powerline noise suppression alone. SP signals showed a linear relationship with water levels observed in the pumping and monitoring wells over the pumping period, with an apparent electrokinetic coupling coefficient of -3.4 mV · m-1. Following recent developments in SP methodology, variability of the SP response between different electrodes is taken as a proxy for lateral variations in hydraulic head within the aquifer and used to infer lateral variations in the aquifer's apparent transmissivity. In order to demonstrate the viability of this approach, SP is modelled numerically to determine its sensitivity to (i) lateral variations in the hydraulic conductivity of the confined aquifer and (ii) the electrical conductivity of the confining layer and conductive well casing. In all cases, SP simulated on the surface still varies linearly with hydraulic head modelled at the base on the confining layer although the apparent coupling coefficient changes to varying degrees. Using the linear relationship observed in the field, drawdown curves were inferred for each electrode location using SP variations observed over the duration of the pumping period. Transmissivity estimates, obtained by fitting the Theis model to inferred drawdown curves at all 31 electrodes, fell within a narrow range of (2.0-4.2) × 10-3 m2

  11. The effect of atmospheric pressure on ventricular assist device output.

    Science.gov (United States)

    Goto, Takeshi; Sato, Masaharu; Yamazaki, Akio; Fukuda, Wakako; Watanabe, Ken-Ichi; Daitoku, Kazuyuki; Minakawa, Masahito; Fukui, Kozo; Suzuki, Yasuyuki; Fukuda, Ikuo

    2012-03-01

    The effect of cabin pressure change on the respiratory system during flight is well documented in the literature, but how the change in atmospheric pressure affects ventricular assist device (VAD) output flow has not been studied yet. The purpose of our study was to evaluate the change in VAD output using a mock circulatory system in a low-pressure chamber mimicking high altitude. Changes in output and driving pressure were measured during decompression from 1.0 to 0.7 atm and pressurization from 0.7 to 1.0 atm. Two driving systems were evaluated: the VCT system and the Mobart system. In the VCT system, output and driving pressure remained the same during decompression and pressurization. In the Mobart system, the output decreased as the atmospheric pressure dropped and recovered during pressurization. The lowest output was observed at 0.7 atm, which was 80% of the baseline driven by the Mobart system. Under a practical cabin pressure of 0.8 atm, the output driven by the Mobart system was 90% of the baseline. In the Mobart system, the output decreased as the atmospheric pressure dropped, and recovered during pressurization. However, the decrease in output was slight. In an environment where the atmospheric pressure changes, it is necessary to monitor the diaphragmatic motion of the blood pump and the driving air pressure, and to adjust the systolic:diastolic ratio as well as the positive and negative pressures in a VAD system.

  12. Augmentation of motor evoked potentials using multi-train transcranial electrical stimulation in intraoperative neurophysiologic monitoring during spinal surgery.

    Science.gov (United States)

    Tsutsui, Shunji; Iwasaki, Hiroshi; Yamada, Hiroshi; Hashizume, Hiroshi; Minamide, Akihito; Nakagawa, Yukihiro; Nishi, Hideto; Yoshida, Munehito

    2015-02-01

    Transcranial motor evoked potentials (TcMEPs) are widely used to monitor motor function during spinal surgery. Improvements in transcranial stimulation techniques and general anesthesia have made it possible to record reliable and reproducible potentials. However, TcMEPs are much smaller in amplitude compared with compound muscle action potentials (CMAPs) evoked by maximal peripheral nerve stimulation. In this study, multi-train transcranial electrical stimulation (mt-TES) was introduced to enhance TcMEPs, and the optimal setting of mt-TES was investigated. In 30 patients undergoing surgical correction of spinal deformities (4 males and 26 females with normal motor status; age range 11-75 years), TcMEPs from the abductor hallucis (AH) and quadriceps femoris (QF) were analyzed. A multipulse (train) stimulus with an individual pulse width of 0.5 ms and an inter-pulse interval of 2 ms was delivered repeatedly (2-7 times) at different rates (2, 5, and 10 Hz). TcMEP amplitudes increased with the number of train stimuli for AH, with the strongest facilitation observed at 5 Hz. The response amplitude increased 6.1 times on average compared with single-train transcranial electrical stimulation (st-TES). This trend was also observed in the QF. No adverse events (e.g., seizures, cardiac arrhythmias, scalp burns, accidental injury resulting from patient movement) were observed in any patients. Although several facilitative techniques using central or peripheral stimuli, preceding transcranial electrical stimulation, have been recently employed to augment TcMEPs during surgery, responses are still much smaller than CMAPs. Changing from conventional st-TES to mt-TES has potential to greatly enhance TcMEP responses.

  13. Space-time data fusion under error in computer model output: an application to modeling air quality.

    Science.gov (United States)

    Berrocal, Veronica J; Gelfand, Alan E; Holland, David M

    2012-09-01

    We provide methods that can be used to obtain more accurate environmental exposure assessment. In particular, we propose two modeling approaches to combine monitoring data at point level with numerical model output at grid cell level, yielding improved prediction of ambient exposure at point level. Extending our earlier downscaler model (Berrocal, V. J., Gelfand, A. E., and Holland, D. M. (2010b). A spatio-temporal downscaler for outputs from numerical models. Journal of Agricultural, Biological and Environmental Statistics 15, 176-197), these new models are intended to address two potential concerns with the model output. One recognizes that there may be useful information in the outputs for grid cells that are neighbors of the one in which the location lies. The second acknowledges potential spatial misalignment between a station and its putatively associated grid cell. The first model is a Gaussian Markov random field smoothed downscaler that relates monitoring station data and computer model output via the introduction of a latent Gaussian Markov random field linked to both sources of data. The second model is a smoothed downscaler with spatially varying random weights defined through a latent Gaussian process and an exponential kernel function, that yields, at each site, a new variable on which the monitoring station data is regressed with a spatial linear model. We applied both methods to daily ozone concentration data for the Eastern US during the summer months of June, July and August 2001, obtaining, respectively, a 5% and a 15% predictive gain in overall predictive mean square error over our earlier downscaler model (Berrocal et al., 2010b). Perhaps more importantly, the predictive gain is greater at hold-out sites that are far from monitoring sites.

  14. Multi-output differential technologies

    Science.gov (United States)

    Bidare, Srinivas R.

    1997-01-01

    A differential is a very old and proven mechanical device that allows a single input to be split into two outputs having equal torque irrespective of the output speeds. A standard differential is capable of providing only two outputs from a single input. A recently patented multi-output differential technology known as `Plural-Output Differential' allows a single input to be split into many outputs. This new technology is the outcome of a systematic study of complex gear trains (Bidare 1992). The unique feature of a differential (equal torque at different speeds) can be applied to simplify the construction and operation of many complex mechanical devices that require equal torque's or forces at multiple outputs. It is now possible to design a mechanical hand with three or more fingers with equal torque. Since these finger are powered via a differential they are `mechanically intelligent'. A prototype device is operational and has been used to demonstrate the utility and flexibility of the design. In this paper we shall review two devices that utilize the new technology resulting in increased performance, robustness with reduced complexity and cost.

  15. Radon progeny monitoring at the Eastern North Atlantic (ENA), Graciosa Island ARM facility and a potential earthquake precursory signal

    Science.gov (United States)

    Barbosa, Susana; Mendes, Virgilio B.; Azevedo, Eduardo B.

    2016-04-01

    Radon has been considered a promising earthquake precursor, the main rationale being an expected increase in radon exhalation in soil and rocks due to stress associated with the preparatory stages of an earthquake. However, the precursory nature of radon is far from being convincingly demonstrated so far. A major hindrance is the many meteorological and geophysical factors diving radon temporal variability, including the geophysical parameters influencing its emanation (grain size, moisture content, temperature), as well as the meteorological factors (atmospheric pressure, moisture, temperature, winds) influencing its mobility. Despite the challenges, radon remains one of the strongest candidates as a potential earthquake precursor, and it is of crucial importance to investigate the many factors driving its variability and its potential association with seismic events. Continuous monitoring of radon progeny is performed at the Eastern North Atlantic (ENA) facility located in the Graciosa island (Azores, 39N; 28W), a fixed site of the Atmospheric Radiation Measurement programme (ARM), established and supported by the Department of Energy (DOE) of the United States of America with the collaboration of the local government and University of the Azores. The Azores archipelago is associated with a complex geodynamic setting on the Azores triple junction where the American, Eurasian and African litospheric plates meet, resulting in significant seismic and volcanic activity. A considerable advantage of the monitoring site is the availability of a comprehensive dataset of concurrent meteorological observations performed at the ENA facility and freely available from the ARM data archive, enabling a detailed analysis of the environmental factors influencing the temporal variability of radon's progeny. Gamma radiation is being measured continuously every 15 minutes since May 2015. The time series of gamma radiation counts is dominated by sharp peaks lasting a few hours and

  16. Monitoring of Plasmodium infection in humans and potential vectors of malaria in a newly emerged focus in southern Iran.

    Science.gov (United States)

    Kalantari, Mohsen; Soltani, Zahra; Ebrahimi, Mostafa; Yousefi, Masoud; Amin, Masoumeh; Shafiei, Ayda; Azizi, Kourosh

    2017-02-01

    Despite control programs, which aim to eliminate malaria from Iran by 2025, transmission of malaria has not been removed from the country. This study aimed to monitor malaria from asymptomatic parasitaemia and clinical cases from about one year of active case surveillance and potential vectors of malaria in the newly emerged focus of Mamasani and Rostam, southern Iran during 2014-2015. Samples were collected and their DNAs were extracted for Polymerase Chain Reaction (PCR) assay using specific primers for detection of Plasmodium species. The Annual Parasite Incidence rate (API) was three cases per 1,000 population from 2,000 individuals in three villages. Parasites species were detected in 9 out of the 4,000 blood smear samples among which, 6 cases were indigenous and had no history of travels to endemic areas of malaria. Also, the prevalence rate of asymptomatic parasites was about 0.3%. Overall, 1073 Anopheles spp. were caught from 9 villages. Totally, 512 female samples were checked by PCR, which indicated that none of them was infected with Plasmodium. Despite new malaria local transmission in humans in Mamasani and Rostam districts, no infection with Plasmodium was observed in Anopheles species. Because of neighboring of the studied area to the re-emerged focus in Fars province (Kazerun) and important endemic foci of malaria in other southern provinces, such as Hormozgan and Kerman, monitoring of the vectors and reservoir hosts of Plasmodium species would be unavoidable. Application of molecular methods, such as PCR, can simplify access to the highest level of accuracy in malaria researches.

  17. Cardiac acceleration at the onset of exercise: a potential parameter for monitoring progress during physical training in sports and rehabilitation.

    Science.gov (United States)

    Hettinga, Florentina J; Monden, Paul G; van Meeteren, Nico L U; Daanen, Hein A M

    2014-05-01

    in relation to physical training primarily incorporated HRonsetlong. HRonsetlong slowed in athletes as well as in patients with a coronary disease, who have a relatively fast HRonsetlong. It is advised to include both HRonsetlong and HRonsetshort in further studies. The findings of this review suggest that HRonset is a potential tool for monitoring and titrating training in sports as well as in rehabilitation settings, particularly in patients with ventricular fibrillation. Monitoring HRonset in the early phase of training can help optimize the effectiveness of training and therapy. More research is needed to gain a better understanding of the mechanisms underlying HRonset in relation to their application in sports and rehabilitation settings.

  18. A one-year monitoring of nicotine use in sport: frontier between potential performance enhancement and addiction issues.

    Science.gov (United States)

    Marclay, François; Grata, Elia; Perrenoud, Laurent; Saugy, Martial

    2011-12-10

    Tobacco consumption is a global epidemic responsible for a vast burden of disease. With pharmacological properties sought-after by consumers and responsible for addiction issues, nicotine is the main reason of this phenomenon. Accordingly, smokeless tobacco products are of growing popularity in sport owing to potential performance enhancing properties and absence of adverse effects on the respiratory system. Nevertheless, nicotine does not appear on the 2011 World Anti-Doping Agency (WADA) Prohibited List or Monitoring Program by lack of a comprehensive large-scale prevalence survey. Thus, this work describes a one-year monitoring study on urine specimens from professional athletes of different disciplines covering 2010 and 2011. A method for the detection and quantification of nicotine, its major metabolites (cotinine, trans-3-hydroxycotinine, nicotine-N'-oxide and cotinine-N-oxide) and minor tobacco alkaloids (anabasine, anatabine and nornicotine) was developed, relying on ultra-high pressure liquid chromatography coupled to triple quadrupole mass spectrometry (UHPLC-TQ-MS/MS). A simple and fast dilute-and-shoot sample treatment was performed, followed by hydrophilic interaction chromatography-tandem mass spectrometry (HILIC-MS/MS) operated in positive electrospray ionization (ESI) mode with multiple reaction monitoring (MRM) data acquisition. After method validation, assessing the prevalence of nicotine consumption in sport involved analysis of 2185 urine samples, accounting for 43 different sports. Concentrations distribution of major nicotine metabolites, minor nicotine metabolites and tobacco alkaloids ranged from 10 (LLOQ) to 32,223, 6670 and 538 ng/mL, respectively. Compounds of interest were detected in trace levels in 23.0% of urine specimens, with concentration levels corresponding to an exposure within the last three days for 18.3% of samples. Likewise, hypothesizing conservative concentration limits for active nicotine consumption prior and/or during

  19. Full Static Output Feedback Equivalence

    Directory of Open Access Journals (Sweden)

    Aristotle G. Yannakoudakis

    2013-01-01

    Full Text Available We present a constructive solution to the problem of full output feedback equivalence, of linear, minimal, time-invariant systems. The equivalence relation on the set of systems is transformed to another on the set of invertible block Bezout/Hankel matrices using the isotropy subgroups of the full state feedback group and the full output injection group. The transformation achieving equivalence is calculated solving linear systems of equations. We give a polynomial version of the results proving that two systems are full output feedback equivalent, if and only if they have the same family of generalized Bezoutians. We present a new set of output feedback invariant polynomials that generalize the breakaway polynomial of scalar systems.

  20. Potential of the Thermal Infrared Wavelength Region to predict semi-arid Soil Surface Properties for Remote Sensing Monitoring

    Science.gov (United States)

    Eisele, Andreas; Chabrillat, Sabine; Lau, Ian; Hecker, Christoph; Hewson, Robert; Carter, Dan; Wheaton, Buddy; Ong, Cindy; Cudahy, Thomas John; Kaufmann, Hermann

    2014-05-01

    Digital soil mapping with the means of passive remote sensing basically relies on the soils' spectral characteristics and an appropriate atmospheric window, where electromagnetic radiation transmits without significant attenuation. Traditionally the atmospheric window in the solar-reflective wavelength region (visible, VIS: 0.4 - 0.7 μm; near infrared, NIR: 0.7 - 1.1 μm; shortwave infrared, SWIR: 1.1 - 2.5 μm) has been used to quantify soil surface properties. However, spectral characteristics of semi-arid soils, typically have a coarse quartz rich texture and iron coatings that can limit the prediction of soil surface properties. In this study we investigated the potential of the atmospheric window in the thermal wavelength region (long wave infrared, LWIR: 8 - 14 μm) to predict soil surface properties such as the grain size distribution (texture) and the organic carbon content (SOC) for coarse-textured soils from the Australian wheat belt region. This region suffers soil loss due to wind erosion processes and large scale monitoring techniques, such as remote sensing, is urgently required to observe the dynamic changes of such soil properties. The coarse textured sandy soils of the investigated area require methods, which can measure the special spectral response of the quartz dominated mineralogy with iron oxide enriched grain coatings. By comparison, the spectroscopy using the solar-reflective region has limitations to discriminate such arid soil mineralogy and associated coatings. Such monitoring is important for observing potential desertification trends associated with coarsening of topsoil texture and reduction in SOC. In this laboratory study we identified the relevant LWIR wavelengths to predict these soil surface properties. The results showed the ability of multivariate analyses methods (PLSR) to predict these soil properties from the soil's spectral signature, where the texture parameters (clay and sand content) could be predicted well in the models

  1. Pulse contour-derived cardiac output in hemodialysis patients

    DEFF Research Database (Denmark)

    Cordtz, Joakim; Ladefoged, Soeren D

    2010-01-01

    Reliable methods for cardiac output determination are essential for studying the pathophysiology of intradialytic hypotension. Use of the current gold standard, the Transonic monitor, requires an arteriovenous fistula. We wished to verify the accuracy of a method based on finger pulse contour...... analysis, namely the Finometer monitor (FNM) for further use on patients dialyzing on a central vascular catheter. Fifty simultaneous cardiac output measurements were obtained during hemodialysis sessions in 25 patients. The internal variability of the FNM measurements was assessed by comparing 24 pairs...

  2. Semiochemicals of the common bed bug, Cimex lectularius L. (Hemiptera: Cimicidae), and their potential for use in monitoring and control.

    Science.gov (United States)

    Weeks, Emma N I; Birkett, Mike A; Cameron, Mary M; Pickett, John A; Logan, James G

    2011-01-01

    The recent resurgence of the common bed bug, Cimex lectularius L., has driven an increase in research into the biology and behaviour of this pest. Current control is reliant on the application of insecticides, but, owing to the development of insecticide resistance, there is a need for new tools and techniques. Semiochemicals (behaviour- and physiology-modifying chemicals) could be exploited for management of bed bugs. The aim of this review was to evaluate studies undertaken in bed bug chemical ecology to date, with particular reference to how the research could be exploited for monitoring and control. Bed bugs, like many other insects, have a complex olfactory system. Recent studies have characterised the olfactory sensilla, located on the terminal segment of the antennae, to functional classes by electrophysiological screening. Behavioural studies have revealed the presence of an alarm pheromone and potential airborne aggregation semiochemicals, but it is not yet understood if bed bugs use a sex pheromone during mating. Host location cues have been investigated, and carbon dioxide has been found to be highly attractive both in laboratory and in field studies. Recent field trials have tested blends of other potential kairomones, which have been shown to have an additive effect when used in a heated bed bug trap with carbon dioxide. The trap, which combines heat and kairomones, is the only trap currently available with proven efficacy in the field. In order for semiochemicals to be useful for bed bug management, an increased knowledge and understanding of the biology, behaviour and chemical ecology of this insect is essential.

  3. Serial auditory-evoked potentials in the diagnosis and monitoring of a child with Landau-Kleffner syndrome.

    Science.gov (United States)

    Plyler, Erin; Harkrider, Ashley W

    2013-01-01

    A boy, aged 2 1/2 yr, experienced sudden deterioration of speech and language abilities. He saw multiple medical professionals across 2 yr. By almost 5 yr, his vocabulary diminished from 50 words to 4, and he was referred to our speech and hearing center. The purpose of this study was to heighten awareness of Landau-Kleffner syndrome (LKS) and emphasize the importance of an objective test battery that includes serial auditory-evoked potentials (AEPs) to audiologists who often are on the front lines of diagnosis and treatment delivery when faced with a child experiencing unexplained loss of the use of speech and language. Clinical report. Interview revealed a family history of seizure disorder. Normal social behaviors were observed. Acoustic reflexes and otoacoustic emissions were consistent with normal peripheral auditory function. The child could not complete behavioral audiometric testing or auditory processing tests, so serial AEPs were used to examine central nervous system function. Normal auditory brainstem responses, a replicable Na and absent Pa of the middle latency responses, and abnormal slow cortical potentials suggested dysfunction of auditory processing at the cortical level. The child was referred to a neurologist, who confirmed LKS. At age 7 1/2 yr, after 2 1/2 yr of antiepileptic medications, electroencephalographic (EEG) and audiometric measures normalized. Presently, the child communicates manually with limited use of oral information. Audiologists often are one of the first professionals to assess children with loss of speech and language of unknown origin. Objective, noninvasive, serial AEPs are a simple and valuable addition to the central audiometric test battery when evaluating a child with speech and language regression. The inclusion of these tests will markedly increase the chance for early and accurate referral, diagnosis, and monitoring of a child with LKS which is imperative for a positive prognosis. American Academy of Audiology.

  4. Potential use of an arthropod database to support the non-target risk assessment and monitoring of transgenic plants.

    Science.gov (United States)

    Romeis, Jörg; Meissle, Michael; Alvarez-Alfageme, Fernando; Bigler, Franz; Bohan, David A; Devos, Yann; Malone, Louise A; Pons, Xavier; Rauschen, Stefan

    2014-12-01

    Worldwide, plants obtained through genetic modification are subject to a risk analysis and regulatory approval before they can enter the market. An area of concern addressed in environmental risk assessments is the potential of genetically modified (GM) plants to adversely affect non-target arthropods and the valued ecosystem services they provide. Environmental risk assessments are conducted case-by-case for each GM plant taking into account the plant species, its trait(s), the receiving environments into which the GM plant is to be released and its intended uses, and the combination of these characteristics. To facilitate the non-target risk assessment of GM plants, information on arthropods found in relevant agro-ecosystems in Europe has been compiled in a publicly available database of bio-ecological information during a project commissioned by the European Food Safety Authority (EFSA). Using different hypothetical GM maize case studies, we demonstrate how the information contained in the database can assist in identifying valued species that may be at risk and in selecting suitable species for laboratory testing, higher-tier studies, as well as post-market environmental monitoring.

  5. Real Aperture Radar interferometry as a tool for buildings vibration monitoring: Limits and potentials from an experimental study

    Science.gov (United States)

    Luzi, Guido; Monserrat, Oriol; Crosetto, Michele

    2012-06-01

    In the last decade several researchers have dealt with the potential of radar interferometry as a remote sensing tool able to provide measurements of vibrations of large structures. More recently the technique has been consolidated thanks to the recent introduction on the market of specifically devoted radar instruments. Exploiting the interferometric capability of coherent radar, successful monitoring of bridges, towers and wind turbine powers has been achieved. This technique allowed looking at the frequency behaviour of civil structures and estimating their amplitude of displacement in the order of fraction of millimetres. The activity here described reports the results of an experimental investigation aimed at evaluating the effectiveness of a coherent Real-Aperture-Radar sensor to estimate the vibration of buildings in an urban environment, through an ambient vibration testing, where the expected amplitude vibration spans within a few to some tens of microns. Critical aspects affecting the retrieval of this information are here discussed, on the basis of some experimental data collected in the last year with a microwave interferometer working at Ku band and available on the market. Preliminary results are shown and suggestions related to the measurement procedures are discussed.

  6. Comparison of auditory evoked potentials and the A-line ARX Index for monitoring the hypnotic level during sevoflurane and propofol induction

    DEFF Research Database (Denmark)

    Litvan, H; Jensen, E W; Revuelta, M

    2002-01-01

    Extraction of the middle latency auditory evoked potentials (AEP) by an auto regressive model with exogenous input (ARX) enables extraction of the AEP within 1.7 s. In this way, the depth of hypnosis can be monitored at almost real-time. However, the identification and the interpretation of the a......Extraction of the middle latency auditory evoked potentials (AEP) by an auto regressive model with exogenous input (ARX) enables extraction of the AEP within 1.7 s. In this way, the depth of hypnosis can be monitored at almost real-time. However, the identification and the interpretation...

  7. Application of pulse index continuous cardiac output monitoring to improve efficiency of acute heart failure care%应用脉搏指数连续心输出量监测提升急性心力衰竭护理效果

    Institute of Scientific and Technical Information of China (English)

    孙秀月; 张领; 赵书琴

    2015-01-01

    Objective To ihvestigate the effect of pulse index continuous cardiac output (PiCCO) monitoring to nursing care of acute heart failure care.Methods The clinical data of 43 acute heart failure patients were retrospectively analyzed,patients were given pulse index continuous cardiac output monitoring and care,the patient' s nursing outcomes were observed,and the intrathoracic blood volume,cardiac output and oxygen consumption before and after the intervention were compared.Results After the implementation of PiCCO and nursing intervention,43 patients had no serious complications,improved 42 cases discharged,the other 1 patient in critical condition due to old age and heart function improvement sustained no automatic discharge.Oxygen consumption,cardiac output and intrathoracic blood volume were improved after the intervention,there was a significant difference (P < 0.05) compared to the previous indicators and intervention after intervention.Conclusions Application of pulse index continuous cardiac output can effectively improve patient's clinical parameters such as cardiac output,through the implementation of appropriate care can improve symptoms and reduce complications.%目的 探讨急性心力衰竭患者护理中应用脉搏指数连续心输出量监测(PiCCO)的效果.方法 选取平顶山市第二人民医院收治的43例急性心力衰竭患者作为研究对象,收集患者的临床资料并对其做回顾性分析,对患者实施脉搏指数连续心输出量监测和护理,对患者的护理效果进行观察,并对其干预前后的胸腔内血容量、心排血量与氧耗量进行对比观察.结果 实施PiCCO和护理干预,本研究43例患者均无严重并发症产生,42例好转出院,1例由于病情危重、高龄及心功能持续无改善自动出院.患者干预后的氧耗量、心排血量与胸腔内血容量均有所改善,干预后各项指标与干预前比较差异有统计学意义(P<0.05).结论 应用脉搏指数连续心

  8. Risk factors for decreased cardiac output after coronary artery bypass grafting: a prospective cohort study.

    Science.gov (United States)

    Dos Santos, Eduarda Ribeiro; Lopes, Camila Takao; Maria, Vera Lucia Regina; de Barros, Alba Lucia Bottura Leite

    2017-04-01

    No previous study has investigated the predictive risk factors of the nursing diagnosis of risk for decreased cardiac output after coronary artery bypass grafting (CABG). This study aimed to identify the predictive risk factors of the nursing diagnosis of risk for decreased cardiac output after CABG. This was a prospective cohort study performed at a cardiac university hospital in São Paulo, Brazil and 257 adult patients undergoing CABG were included. Potential risk factors for low cardiac output in the immediate post-operative period were investigated using the patients' medical records. Univariate analysis and logistic regression were used to identify the predictive risk factors of decreased cardiac output. The area under the receiver operating characteristic curve was calculated as a measure of accuracy. The variables that could not be analysed through logistic regression were analysed through Fisher's exact test. One hundred and ninety-five patients had low cardiac output in the immediate post-operative period. The predictive risk factors included age ⩾60 years, decreased left ventricle ejection fraction, not using the radial artery graft, positive fluid balance and post-operative arrhythmia that differed from the pre-operative arrhythmia. This model predicted the outcome with a sensitivity of 62.9%, a specificity of 87.2% and an accuracy of 81.5%. The variables analysed through Fisher's exact test included heart failure, re-exploration and bleeding-related re-exploration. The predictive risk factors for the nursing diagnosis of risk for decreased cardiac output after CABG were found. These results can be used to direct nurses in patient monitoring, staff training and nursing team staffing.

  9. Potential for Using Acetic Acid Plus Pear Ester Combination Lures to Monitor Codling Moth in an SIT Program

    Directory of Open Access Journals (Sweden)

    Gary J. R. Judd

    2016-11-01

    Full Text Available Studies were conducted in commercial apple orchards in British Columbia, Canada, to determine whether lures combining ethyl-(E,Z-2,4-decadienoate, pear ester (PE, with either acetic acid (AA or sex pheromone, (E,E-8,10-dodecadien-1-ol (codlemone, might improve monitoring of codling moth, Cydia pomonella (L., in an area-wide programme integrating sterile insect technology (SIT and mating disruption (MD. Catches of sterile and wild codling moths were compared in apple orchards receiving weekly delivery of sterile moths (1:1 sex ratio using white delta traps baited with either AA or PE alone, and in combination. Sterile and wild codling moths responded similarly to these kairomone lures. For each moth sex and type (sterile and wild, AA-PE lures were significantly more attractive than AA or PE alone. Bisexual catches with AA-PE lures were compared with those of commercial bisexual lures containing 3 mg of codlemone plus 3 mg of PE (Pherocon CM-DA Combo lure, Trécé Inc., Adair, OK, USA, and to catches of males with standard codlemone-loaded septa used in SIT (1 mg and MD (10 mg programmes, respectively. CM-DA lures caught the greatest number of sterile and wild male moths in orchards managed with SIT alone, or combined with MD, whereas AA-PE lures caught 2–3× more females than CM-DA lures under both management systems. Sterile to wild (S:W ratios for male versus female moths in catches with AA-PE lures were equivalent, whereas in the same orchards, male S:W ratios were significantly greater than female S:W ratios when measured with CM-DA lures. Male S:W ratios measured with CM-DA lures were similar to those with codlemone lures. CM-DA and codlemone lures appear to overestimate S:W ratios as measured by AA-PE lures, probably by attracting relatively more sterile males from long range. Using AA-PE lures to monitor codling moths in an SIT programme removes fewer functional sterile males and reduces the need for trap maintenance compared with using

  10. Potential for Using Acetic Acid Plus Pear Ester Combination Lures to Monitor Codling Moth in an SIT Program.

    Science.gov (United States)

    Judd, Gary J R

    2016-11-25

    Studies were conducted in commercial apple orchards in British Columbia, Canada, to determine whether lures combining ethyl-(E,Z)-2,4-decadienoate, pear ester (PE), with either acetic acid (AA) or sex pheromone, (E,E)-8,10-dodecadien-1-ol (codlemone), might improve monitoring of codling moth, Cydia pomonella (L.), in an area-wide programme integrating sterile insect technology (SIT) and mating disruption (MD). Catches of sterile and wild codling moths were compared in apple orchards receiving weekly delivery of sterile moths (1:1 sex ratio) using white delta traps baited with either AA or PE alone, and in combination. Sterile and wild codling moths responded similarly to these kairomone lures. For each moth sex and type (sterile and wild), AA-PE lures were significantly more attractive than AA or PE alone. Bisexual catches with AA-PE lures were compared with those of commercial bisexual lures containing 3 mg of codlemone plus 3 mg of PE (Pherocon CM-DA Combo lure, Trécé Inc., Adair, OK, USA), and to catches of males with standard codlemone-loaded septa used in SIT (1 mg) and MD (10 mg) programmes, respectively. CM-DA lures caught the greatest number of sterile and wild male moths in orchards managed with SIT alone, or combined with MD, whereas AA-PE lures caught 2-3× more females than CM-DA lures under both management systems. Sterile to wild (S:W) ratios for male versus female moths in catches with AA-PE lures were equivalent, whereas in the same orchards, male S:W ratios were significantly greater than female S:W ratios when measured with CM-DA lures. Male S:W ratios measured with CM-DA lures were similar to those with codlemone lures. CM-DA and codlemone lures appear to overestimate S:W ratios as measured by AA-PE lures, probably by attracting relatively more sterile males from long range. Using AA-PE lures to monitor codling moths in an SIT programme removes fewer functional sterile males and reduces the need for trap maintenance compared with using

  11. Self-potential monitoring of a crude oil contaminated site (Trecate, Italy): first results of the modelling.

    Science.gov (United States)

    Giampaolo, V.; Rizzo, E.; Titov, K.; Maineult, A.; Lapenna, V.

    2012-04-01

    The contamination of soils and groundwater by hydrocarbon, due to blow out, leakage from tank or pipe and oil spill, is a heavy environmental problem because infiltrated oil can persist in the ground for a long time. The existing methods used for the remediation of these contaminated sites are invasive, time consuming and expensive. Therefore, in the last years, there was a growing interest in the use of geophysical methods for environmental monitoring (Atekwana et al., 2000; Chambers et al., 2004; Song et al., 2005; French et al., 2009). A particular attention is given to the self-potential (SP) method because SP is sensitive to the contaminant chemistry and redox processes generated by bacteria during the biodegradation (Atekwana et al., 2004; Naudet and Revil, 2005; Revil et al., 2010). Here we show the results of SP investigations carried out at Trecate site (Italy). This site was affected by a crude oil contamination from a well blowout in 1994. Four SP surveys (October 2009, March 2010, October 2010, and March 2011) were conducted at the site, both in the contaminated and uncontaminated regions. Significant changes are observed between SP data collected at different times. In particular, we found mostly negative electrical potential in October surveys and positive electrical potential in March surveys. The SP distributions can be interpreted as the superposition of many components, including a horizontal water-flow in the saturated shallow aquifer toward South-East, the infiltration movement of water in the unsaturated zone and, possibly, the oxidation-reduction phenomena due to bacterial activity. As the groundwater flow usually produces SP linear trends, the data were detrended by linear regression, taking into account the measured piezometric heads in the aquifer. The detrended SP data show that the SP distribution within the contaminated zone is generally bipolar in October: the southern part of the contaminated area is characterized by negative values

  12. Research management and research output

    Directory of Open Access Journals (Sweden)

    Anita Bosch

    2011-12-01

    Full Text Available Purpose: A study was conducted at two merged South African higher education institutions to determine which management factors, as identified in a literature study as well as through a factor analysis of survey data, were predictive of the dependent variable 'research output'. Problem investigated: Research output contributes to creating sustainability of knowledge of management sciences and therefore the active management of research is in the interest of progressive universities. Research management related activities are usually associated with measurable targets, detailed plans, rigorous evaluation and decisive action - all of which are observable (perhaps programmable behaviour also referred to as tangible factors. Authors argue that the tangible factors of any successful institution can be copied, technology can be bought, and in theory you should have an instantly thriving research institution. It is, however, clear that although many institutions have exactly the same technology and structure as their successful competitors, they still fail to succeed in increasing research output. Design and Research methodology or approach: A survey was distributed to n=411 and yielded a 49.6% response rate. A confirmatory reliability analysis as well as a factor analysis was conducted. Findings/implications: The empirical model that was derived through a factor analysis strengthens the argument that both tangible and intangible factors exist in a research environment. Tangible and intangible factors play a different role in predicting research output. The tangible factors are predictors of research output for non-research-active academics. The theoretical research output prediction model highlights predictors such as 'professional activities' and 'individual skills and competence' for specific groupings. The theoretical model indicates that the factors that predict research output are largely intrinsic to a researcher but could also be supported by

  13. Monitoring and mitigating measures to reduce potential impacts of oil and gas exploration and development on bears in the Inuvik region

    Energy Technology Data Exchange (ETDEWEB)

    Branigan, M. [Government of the Northwest Territories, Inuvik, NT (Canada). Dept. of Environment and Natural Resources

    2007-07-01

    The Inuvik Region consists of the Northwest Territories portion of the Inuvialuit Settlement Region and the Gwich'in Settlement Area. The range of grizzly bears, polar bears and black bears extends to different parts of the region. The potential impact of development depends on the season of the development and the species of bear found in the footprint. As such, monitoring and mitigation measures should take this into consideration. This presentation focused on the potential impacts and current practices to monitor and mitigate the impacts in the region. Mitigation measures currently used include: communication with stakeholders; waste management guidelines; use of wildlife monitors to identify key habitat and den sites and to deter bears; minimum flight altitudes; and safety training. Suggestions for additional mitigation measures were also presented. figs.

  14. Body monitoring and imaging apparatus and method

    Energy Technology Data Exchange (ETDEWEB)

    McEwan, T.E.

    1998-06-16

    A non-acoustic pulse-echo radar monitor is employed in the repetitive mode, whereby a large number of reflected pulses are averaged to produce a voltage that modulates an audio oscillator to produce a tone that corresponds to the heart motion. The antenna used in this monitor generally comprises two flat copper foils, thus permitting the antenna to be housed in a substantially flat housing. The monitor converts the detected voltage to an audible signal with both amplitude modulation and Doppler effect. It further uses a dual time constant to reduce the effect of gross sensor-to-surface movement. The monitor detects the movement of one or more internal body parts, such as the heart, lungs, arteries, and vocal chords, and includes a pulse generator for simultaneously inputting a sequence of pulses to a transmit path and a grating path. The pulses transmitted along the transmit path drive Oh impulse, generator and provide corresponding transmit pulses that are applied to a transmit antenna. The gating path includes a range delay generator which generates timed gating pulses. The timed gating pulses cause the receive path to selectively conduct pulses reflected from the body parts and received by a receive antenna. The monitor output potential can be separated into a cardiac output indicative of the physical movement of the heart, and a pulmonary output indicative of the physical movement of the lung. The impulse generator in the transmit path can be replaced with a pulsed RF generator. 13 figs.

  15. Body monitoring and imaging apparatus and method

    Energy Technology Data Exchange (ETDEWEB)

    McEwan, T.E.

    1996-11-12

    A non-acoustic pulse-echo radar monitor is employed in the repetitive mode, whereby a large number of reflected pulses are averaged to produce a voltage that modulates an audio oscillator to produce a tone that corresponds to the heart motion. The antenna used in this monitor generally comprises two flat copper foils, thus permitting the antenna to be housed in a substantially flat housing. The monitor converts the detected voltage to an audible signal with both amplitude modulation and Doppler effect. It further uses a dual time constant to reduce the effect of gross sensor-to-surface movement. The monitor detects the movement of one or more internal body parts, such as the heart, lungs, arteries, and vocal chords, and includes a pulse generator for simultaneously inputting a sequence of pulses to a transmit path and a gating path. The pulses transmitted along the transmit path drive an impulse generator and provide corresponding transmit pulses that are applied to a transmit antenna. The gating path includes a range delay generator which generates timed gating pulses. The timed gating pulses cause the receive path to selectively conduct pulses reflected from the body parts and received by a receive antenna. The monitor output potential can be separated into a cardiac output indicative of the physical movement of the heart, and a pulmonary output indicative of the physical movement of the lung. 12 figs.

  16. Body monitoring and imaging apparatus and method

    Energy Technology Data Exchange (ETDEWEB)

    McEwan, Thomas E. (Livermore, CA)

    1998-01-01

    A non-acoustic pulse-echo radar monitor is employed in the repetitive mode, whereby a large number of reflected pulses are averaged to produce a voltage that modulates an audio oscillator to produce a tone that corresponds to the heart motion. The antenna used in this monitor generally comprises two flat copper foils, thus permitting the antenna to be housed in a substantially flat housing. The monitor converts the detected voltage to an audible signal with both amplitude modulation and Doppler effect. It further uses a dual time constant to reduce the effect of gross sensor-to-surface movement. The monitor detects the movement of one or more internal body parts, such as the heart, lungs, arteries, and vocal chords, and includes a pulse generator for simultaneously inputting a sequence of pulses to a transmit path and a grating path. The pulses transmitted along the transmit path drive Oh impulse, generator and provide corresponding transmit pulses that are applied to a transmit antenna. The gating path includes a range delay generator which generates timed gating pulses. The timed gating pulses cause the receive path to selectively conduct pulses reflected from the body parts and received by a receive antenna. The monitor output potential can be separated into a cardiac output indicative of the physical movement of the heart, and a pulmonary output indicative of the physical movement of the lung. The impulse generator in the transmit path can be replaced with a pulsed RF generator.

  17. Body monitoring and imaging apparatus and method

    Energy Technology Data Exchange (ETDEWEB)

    McEwan, Thomas E. (Livermore, CA)

    1996-01-01

    A non-acoustic pulse-echo radar monitor is employed in the repetitive mode, whereby a large number of reflected pulses are averaged to produce a voltage that modulates an audio oscillator to produce a tone that corresponds to the heart motion. The antenna used in this monitor generally comprises two flat copper foils, thus permitting the antenna to be housed in a substantially flat housing. The monitor converts the detected voltage to an audible signal with both amplitude modulation and Doppler effect. It further uses a dual time constant to reduce the effect of gross sensor-to-surface movement. The monitor detects the movement of one or more internal body parts, such as the heart, lungs, arteries, and vocal chords, and includes a pulse generator for simultaneously inputting a sequence of pulses to a transmit path and a gating path. The pulses transmitted along the transmit path drive an impulse generator and provide corresponding transmit pulses that are applied to a transmit antenna. The gating path includes a range delay generator which generates timed gating pulses. The timed gating pulses cause the receive path to selectively conduct pulses reflected from the body parts and received by a receive antenna. The monitor output potential can be separated into a cardiac output indicative of the physical movement of the heart, and a pulmonary output indicative of the physical movement of the lung.

  18. NMR techniques for determination of lipid content in microalgal biomass and their use in monitoring the cultivation with biodiesel potential.

    Science.gov (United States)

    Sarpal, Amarjit S; Teixeira, Cláudia M L L; Silva, Paulo Roque Martins; da Costa Monteiro, Thays Vieira; da Silva, Júlia Itacolomy; da Cunha, Valnei Smarcaro; Daroda, Romeu José

    2016-03-01

    In the present investigation, the application of NMR spectroscopic techniques was extensively used with an objective to explore the biodiesel potential of biomass cultivated on a lab scale using strains of Chlorella vulgaris and Scenedesmus ecornis. The effect of variation in the composition of culturing medium on the neutral and polar lipids productivity, and fatty acid profile of solvent extracts of microalgae biomass was studied. Determination of unsaturated fatty acid composition (C18:N = 1-3, ω3 C20:5, ω3 C22:6), polyunsaturated fatty esters (PUFEs), saturated fatty acids (SFAs), unsaturated fatty acids (UFAs), free fatty acids (FFAs), and iodine value were achieved from a single (1)H NMR spectral analysis. The results were validated by (13)C NMR and GC-MS analyses. It was demonstrated that newly developed methods based on (1)H and (13)C NMR techniques are direct, rapid, and convenient for monitoring the microalgae cultivation process for enhancement of lipid productivity and their quality aspects in the solvent extracts of microalgal biomasses without any sample treatment and prior separation compared to other methods. The fatty acid composition of algae extracts was found to be similar to vegetable and fish oils, mostly rich in C16:0, C18:N (N = 0 to 3), and n-3 omega polyunsaturated fatty acids (PUFAs). The lipid content, particularly neutral lipids, as well as most of the quality parameters were found to be medium specific by both the strains. The newly developed methods based on NMR and ultrasonic procedure developed for efficient extraction of neutral lipids are cost economic and can be an effective aid for rapid screening of algae strains for modulation of lipid productivity with desired biodiesel quality and value-added products including fatty acid profile.

  19. A new method for temperature-field reconstruction during ultrasound-monitored cryosurgery using potential-field analogy.

    Science.gov (United States)

    Thaokar, Chandrajit; Rossi, Michael R; Rabin, Yoed

    2016-02-01

    The current study aims at developing computational tools in order to gain information about the thermal history in areas invisible to ultrasound imaging during cryosurgery. This invisibility results from the high absorption rate of the ultrasound energy by the frozen region, which leads to an apparent opacity in the cryotreated area and a shadow behind it. A proof-of-concept for freezing-front estimation is demonstrated in the current study, using the new potential-field analogy method (PFAM). This method is further integrated with a recently developed temperature-field reconstruction method (TFRM) to estimate the temperature distribution within the frozen region. This study uses prostate cryosurgery as a developmental model and trans-rectal ultrasound imaging as a choice of practice. Results of this study indicate that the proposed PFAM is a viable and computationally inexpensive solution to estimate the extent of freezing in the acoustic shadow region. Comparison of PFAM estimations and experimental data shows an average mismatch of less than 2 mm in freezing-front location, which is comparable to the uncertainty in ultrasound imaging. Comparison of the integrated PFAM + TFRM scheme with a full-scale finite-elements analysis (FEA) indicates an average mismatch of 0.9 mm for the freezing front location and 0.1 mm for the lethal temperature isotherm of -45 °C. Comparison of the integrated PFAM + TFRM scheme with experimental temperature measurements show a difference in the range of 2 °C and 6 °C for selected points of measurement. Results of this study demonstrate the integrated PFAM + TFRM scheme as a viable and computationally inexpensive means to gain information about the thermal history in the frozen region during ultrasound-monitored cryosurgery.

  20. Comparison of auditory evoked potentials and the A-line ARX Index for monitoring the hypnotic level during sevoflurane and propofol induction

    DEFF Research Database (Denmark)

    Litvan, H; Jensen, E W; Revuelta, M

    2002-01-01

    Extraction of the middle latency auditory evoked potentials (AEP) by an auto regressive model with exogenous input (ARX) enables extraction of the AEP within 1.7 s. In this way, the depth of hypnosis can be monitored at almost real-time. However, the identification and the interpretation of the a...

  1. Pulse contour-derived cardiac output in hemodialysis patients

    DEFF Research Database (Denmark)

    Cordtz, Joakim; Ladefoged, Soeren D

    2010-01-01

    Reliable methods for cardiac output determination are essential for studying the pathophysiology of intradialytic hypotension. Use of the current gold standard, the Transonic monitor, requires an arteriovenous fistula. We wished to verify the accuracy of a method based on finger pulse contour...

  2. Assessment of potential long-range transport of particulate air pollution using trajectory modeling and monitoring data

    Science.gov (United States)

    Pongkiatkul, Prapat; Kim Oanh, Nguyen Thi

    2007-07-01

    Quantification of the long-range transport (LRT) contribution to ambient air pollution levels at a location is a challenging task and is normally done with a high uncertainty. In the lack of accurate emission data over the large regional domain for dispersion modeling, this study attempts to use both trajectory analysis and monitoring data to assess the potential contribution of LRT to particulate air pollution (PM) in the Bangkok Metropolitan Region (BMR). The 10-day backward trajectories of air masses arriving at BMR from January 2002 to December 2004 were determined using Hybrid Single-Particle Langrangian Integrated Trajectory model version 4 (HYSPLIT4) and were categorized by k-means clustering into 6 clusters. Subsequently, PM levels in the BMR associated with each air mass cluster during this period were analyzed. Clusters 1 and 6 were observed with the highest and 2nd highest average PM 10 and PM 2.5 levels in the BMR, respectively, which commonly have a longer air mass pathway over populated South East Asia (SEA). The third highest PM levels were associated with air masses from the east (clusters 2 and 5), which enter the BMR via the Gulf of Thailand without passing the SEA regions. The other two clusters (3 and 4) are characterized with a long pathway of air masses over the Indian Ocean and the lowest PM levels. High PM days, which are defined based on the spatial coverage of high PM levels in the BMR, were identified and analyzed for the possibility of long-range transport contribution of PM. The potential source contribution function (PSCF) and air mass trajectories show that on high PM day, the air masses commonly originated and passed over populated regions before arriving at the BMR, which suggests a possible LRT contribution. Considerations are made for surface ozone, SO 42-/SO 2 and average SO 2, PM 2.5/PM 10, and weekday-weekend traffic emission within each air mass trajectory cluster to reveal the possible LRT contribution.

  3. World Input-Output Network.

    Directory of Open Access Journals (Sweden)

    Federica Cerina

    Full Text Available Production systems, traditionally analyzed as almost independent national systems, are increasingly connected on a global scale. Only recently becoming available, the World Input-Output Database (WIOD is one of the first efforts to construct the global multi-regional input-output (GMRIO tables. By viewing the world input-output system as an interdependent network where the nodes are the individual industries in different economies and the edges are the monetary goods flows between industries, we analyze respectively the global, regional, and local network properties of the so-called world input-output network (WION and document its evolution over time. At global level, we find that the industries are highly but asymmetrically connected, which implies that micro shocks can lead to macro fluctuations. At regional level, we find that the world production is still operated nationally or at most regionally as the communities detected are either individual economies or geographically well defined regions. Finally, at local level, for each industry we compare the network-based measures with the traditional methods of backward linkages. We find that the network-based measures such as PageRank centrality and community coreness measure can give valuable insights into identifying the key industries.

  4. World Input-Output Network

    Science.gov (United States)

    Cerina, Federica; Zhu, Zhen; Chessa, Alessandro; Riccaboni, Massimo

    2015-01-01

    Production systems, traditionally analyzed as almost independent national systems, are increasingly connected on a global scale. Only recently becoming available, the World Input-Output Database (WIOD) is one of the first efforts to construct the global multi-regional input-output (GMRIO) tables. By viewing the world input-output system as an interdependent network where the nodes are the individual industries in different economies and the edges are the monetary goods flows between industries, we analyze respectively the global, regional, and local network properties of the so-called world input-output network (WION) and document its evolution over time. At global level, we find that the industries are highly but asymmetrically connected, which implies that micro shocks can lead to macro fluctuations. At regional level, we find that the world production is still operated nationally or at most regionally as the communities detected are either individual economies or geographically well defined regions. Finally, at local level, for each industry we compare the network-based measures with the traditional methods of backward linkages. We find that the network-based measures such as PageRank centrality and community coreness measure can give valuable insights into identifying the key industries. PMID:26222389

  5. Remote input/output station

    CERN Multimedia

    1972-01-01

    A general view of the remote input/output station installed in building 112 (ISR) and used for submitting jobs to the CDC 6500 and 6600. The card reader on the left and the line printer on the right are operated by programmers on a self-service basis.

  6. World Input-Output Network.

    Science.gov (United States)

    Cerina, Federica; Zhu, Zhen; Chessa, Alessandro; Riccaboni, Massimo

    2015-01-01

    Production systems, traditionally analyzed as almost independent national systems, are increasingly connected on a global scale. Only recently becoming available, the World Input-Output Database (WIOD) is one of the first efforts to construct the global multi-regional input-output (GMRIO) tables. By viewing the world input-output system as an interdependent network where the nodes are the individual industries in different economies and the edges are the monetary goods flows between industries, we analyze respectively the global, regional, and local network properties of the so-called world input-output network (WION) and document its evolution over time. At global level, we find that the industries are highly but asymmetrically connected, which implies that micro shocks can lead to macro fluctuations. At regional level, we find that the world production is still operated nationally or at most regionally as the communities detected are either individual economies or geographically well defined regions. Finally, at local level, for each industry we compare the network-based measures with the traditional methods of backward linkages. We find that the network-based measures such as PageRank centrality and community coreness measure can give valuable insights into identifying the key industries.

  7. Input/output interface module

    Science.gov (United States)

    Ozyazici, E. M.

    1980-01-01

    Module detects level changes in any of its 16 inputs, transfers changes to its outputs, and generates interrupts when changes are detected. Up to four changes-in-state per line are stored for later retrieval by controlling computer. Using standard TTL logic, module fits 19-inch rack-mounted console.

  8. Judicial Influence on Policy Outputs?

    DEFF Research Database (Denmark)

    Martinsen, Dorte Sindbjerg

    2015-01-01

    ) social policy outputs. A taxonomy of judicial influence is constructed, and expectations of institutional and political conditions on judicial influence are presented. The analysis draws on an extensive novel data set and examines judicial influence on EU social policies over time, that is, between 1958...

  9. Inductive Output Tubes -- Status and Future Direction

    Science.gov (United States)

    Bohlen, Heinz

    2002-08-01

    Invented in 1938, at the same time as the klystron, it took the Inductive Output Tube (IOT) more than 40 years to surface as a useful device. Its progress after that event was rapid. Though plagued by teething problems in the beginning, it has since replaced the klystron as a TV amplifier in UHF, and it holds its own against the solid-state competition in that application. The IOT also shows much promise as a high-power amplifier, but early developments in this direction have remained solitary events so far. The paper discusses the causes and the potential of the device for future high-power applications.

  10. Environmental monitoring techniques and wave energy potential assessment: an integrated approach for planning marine energy conversion schemes in the northern Tyrrhenian sea, Italy

    Science.gov (United States)

    Scanu, Sergio; Peviani, Maximo; Carli, Filippo Maria; Paladini de Mendoza, Francesco; Piermattei, Viviana; Bonamano, Simone; Marcelli, Marco

    2015-04-01

    This work proposes a multidisciplinary approach in which wave power potential maps are used as baseline for the application of environmental monitoring techniques identified through the use of a Database for Environmental Monitoring Techniques and Equipment (DEMTE), derived in the frame of the project "Marine Renewables Infrastructure Network for Emerging Energy Technologies" (Marinet - FP7). This approach aims to standardize the monitoring of the marine environment in the event of installation, operation and decommissioning of Marine Energy Conversion Systems. The database has been obtained through the collection of techniques and instrumentation available among the partners of the consortium, in relation with all environmental marine compounds potentially affected by any impacts. Furthermore in order to plan marine energy conversion schemes, the wave potential was assessed at regional and local scales using the numerical modelling downscaling methodology. The regional scale lead to the elaboration of the Italian Wave Power Atlas, while the local scale lead to the definition of nearshore hot spots useful for the planning of devices installation along the Latium coast. The present work focus in the application of environmental monitoring techniques identified in the DEMTE, in correspondence of the hotspot derived from the wave potential maps with particular reference to the biological interaction of the devices and the management of the marine space. The obtained results are the bases for the development of standardized procedures which aims to an effective application of marine environmental monitoring techniques during the installation, operation and decommissioning of Marine Energy Conversion Systems. The present work gives a consistent contribution to overcome non-technological barriers in the concession procedures, as far as the protection of the marine environment is of concern.

  11. UFO - The Universal FEYNRULES Output

    Science.gov (United States)

    Degrande, Céline; Duhr, Claude; Fuks, Benjamin; Grellscheid, David; Mattelaer, Olivier; Reiter, Thomas

    2012-06-01

    We present a new model format for automatized matrix-element generators, the so-called Universal FEYNRULES Output (UFO). The format is universal in the sense that it features compatibility with more than one single generator and is designed to be flexible, modular and agnostic of any assumption such as the number of particles or the color and Lorentz structures appearing in the interaction vertices. Unlike other model formats where text files need to be parsed, the information on the model is encoded into a PYTHON module that can easily be linked to other computer codes. We then describe an interface for the MATHEMATICA package FEYNRULES that allows for an automatic output of models in the UFO format.

  12. Pulse Indicator Continuous Cardiac Output for Hemodynamics Monitoring in Patients with Septic Shock%脉搏指示连续心排血量监测(PiCCO)在脓毒症休克患者血流动力学监测中的临床价值

    Institute of Scientific and Technical Information of China (English)

    陈涛

    2015-01-01

    Objective To observe and analyze patients with septic shock pulse wave indicates continuous cardiac output monitoring (Picco) clinical value, to provide a reference for future clinical use. Methods January 2013—2014 in March during outpatient sep-sis patients admitted to 40 cases for the study, depending on the admission of hemodynamic monitoring methods divided into two groups, the study group and the control group 20 cases. Two were used for routine monitoring (control group), Picco monitoring (study group) to guide clinical treatment (fluid resuscitation, inotropic drugs, vasoconstrictor drugs, etc.). Results The mean arterial pressure in the two groups of patients after treatment of the initial value and compare, P 0.05). Conclusion Picco be monitored in patients with septic shock hemodynamic parameters with good results, it is worth further study in late.%目的:观察脓毒症休克患者采用脉波指示连续心排血量监测(PiCCO)的效果,并分析其临床应用价值。方法将医院2012年1月—2014年3月期间门诊收入的脓毒症50例患者选为研究对象,按照患者就诊时血动力指标的监测方式不同分成两组:研究组25例,对照组25例。两组分别采用常规监测(对照组)、PiCCO监测(研究组)指导临床治疗(液体复苏、正性肌力药物、血管收缩药物等)。结果两组患者的平均动脉压在初始值比较(P<0.01);研究组患者入院3 d内不同时点GEDI、PPV、SVV检测值比较,组间差异有统计学意义(P<0.05)。组间在去甲肾上腺素和就诊1周输液量比较,差异无统计学意义(P>0.05)。结论脓毒症休克患者予以PiCCO监测血流动力学指标具有良好效果,值得在后期进一步研究。

  13. Determining state-space models from sequential output data

    Science.gov (United States)

    Lin, Jiguan Gene

    1988-01-01

    This talk focuses on the determination of state-space models for large space systems using only the output data. The output data could be generated by the unknown or deliberate initial conditions of the space structure in question. We shall review some relevant fundamental work on the state-space modeling of sequential output data that is potentially applicable to large space structures. If formulated in terms of some generalized Markov parameters, this approach is in some sense similar to, but much simpler than, the Juang-Pappa Eigensystem Realization Algorithm (ERA) and the Ho-Kalman construction procedure.

  14. ESTIMATING THE OUTPUT GAP FOR ROMANIA’S ECONOMY

    Directory of Open Access Journals (Sweden)

    Belingher Daniel

    2014-12-01

    Full Text Available In this research paper the authors try to estimate Romania’s Output Gap and how the country managed to evolve, from the given chronological perspective, in parallel with the estimated potential Output Gap. Romania started to feel the heat of the economic crisis at almost three quarters after the American economy started its decline, but when it comes to the economy’s Output Gap, the country macro-behaved with a pace somehow differentiated in parallel with the global economy. Where was Romania and where it is heading that is the question that this research paper tries to answer from macroeconomic perspective.

  15. Monitoring and management of Cerambyx cerdo in the Mediterranean region – a review and the potential role of citizen science

    Directory of Open Access Journals (Sweden)

    Paolo Casula

    2017-07-01

    Full Text Available The Great Capricorn beetle, Cerambyx cerdo, and Mediterranean oak habitats (Quercus ilex – 9340 and Quercus suber – 9330 are protected by the Habitats Directive (HD. However, in the Mediterranean basin, these habitats are also traditionally used for animal, wood, and cork productions. Cerambyx cerdo feeds into the wood of trees and can be perceived by forest practitioners as an umbrella species or as a pest, depending on the context. Monitoring programmes involving forest practitioners could thus focus on assessing: 1 the conservation status of the Great Capricorn beetle and habitats (distribution and abundance of insects and reproductive sites or colonised trees, 2 pest status, and 3 management options to achieve both conservational and economic benefits. Considering that Cerambyx cerdo and Cork and Holm oak forests are not priority species or habitats under the HD, targeted funding is likely to be limited for monitoring. In this context, citizen science could gather important information on the target species useful for the monitoring programmes and management. To address management questions, the citizen science based programme for Cerambyx cerdo monitoring and habitat conservation should be seen not only as citizens collecting good data sets, but also as a deeper collaboration amongst different knowledge bodies and perspectives within a community – based environmental monitoring and learning network.

  16. The potential of computer vision, optical backscattering parameters and artificial neural network modelling in monitoring the shrinkage of sweet potato (Ipomoea batatas L.) during drying.

    Science.gov (United States)

    Onwude, Daniel I; Hashim, Norhashila; Abdan, Khalina; Janius, Rimfiel; Chen, Guangnan

    2017-07-30

    Drying is a method used to preserve agricultural crops. During the drying of products with high moisture content, structural changes in shape, volume, area, density and porosity occur. These changes could affect the final quality of dried product and also the effective design of drying equipment. Therefore, this study investigated a novel approach in monitoring and predicting the shrinkage of sweet potato during drying. Drying experiments were conducted at temperatures of 50-70 °C and samples thicknesses of 2-6 mm. The volume and surface area obtained from camera vision, and the perimeter and illuminated area from backscattered optical images were analysed and used to evaluate the shrinkage of sweet potato during drying. The relationship between dimensionless moisture content and shrinkage of sweet potato in terms of volume, surface area, perimeter and illuminated area was found to be linearly correlated. The results also demonstrated that the shrinkage of sweet potato based on computer vision and backscattered optical parameters is affected by the product thickness, drying temperature and drying time. A multilayer perceptron (MLP) artificial neural network with input layer containing three cells, two hidden layers (18 neurons), and five cells for output layer, was used to develop a model that can monitor, control and predict the shrinkage parameters and moisture content of sweet potato slices under different drying conditions. The developed ANN model satisfactorily predicted the shrinkage and dimensionless moisture content of sweet potato with correlation coefficient greater than 0.95. Combined computer vision, laser light backscattering imaging and artificial neural network can be used as a non-destructive, rapid and easily adaptable technique for in-line monitoring, predicting and controlling the shrinkage and moisture changes of food and agricultural crops during drying. © 2017 Society of Chemical Industry. © 2017 Society of Chemical Industry.

  17. Clinical evaluation of the accuracy of the USCOM ultrasonic cardiac output monitor in the septic shock patients%无创超声心输出量测定对急诊感染性休克患者血流动力学状态评价的临床研究

    Institute of Scientific and Technical Information of China (English)

    刘继海; 于学忠; 王仲; 朱华栋; 徐胜勇

    2011-01-01

    目的 对急诊感染性休克患者同时进行脉搏波形指示的连续心输出量(pulse indicated continuous cardiac output, PiCCO)监测技术和无创超声心输出量测定,以有创血流动力学监测的数值作为标准,对无创超声心输出量测定方法的可靠性进行评价.方法 本试验为前瞻性研究,2008-06~2009-06北京协和医院急诊科抢救室和EICU收治32例明确诊断为感染性休克的患者,对这些患者同时进行无创超声心输出量测定和PiCCO监测,对比两者在心脏指数(cardiac index, CI)这一血流动力学核心指标上的差异,以评价无创超声心输出量测定在急诊应用中的可靠性.结果 共有30例患者同时获得了满意的血流超声多普勒影像,其中男性20例,女性10例,最小年龄26岁,最大年龄89岁,另2例患者因无法获得满意的超声结果而放弃.对比结果显示,在获得满意超声多普勒影像的前提下,无创超声心输出量和PiCCO测定的CI分别为(3.89±1.61)L/(min·m2)和(4.35±1.72)L/(min·m2)(Pearson相关系数=0.97165,P<0.0001).结论 无创超声心输出量测定是一项准确、快速、安全、无创的血流动力学监测技术,比较适合急诊患者的应用.%Objective The USCOM ultrasonic cardiac output monitor ( USCOM Pty Ltd, Coffs Harbour, NSW, Australia) is a non - invasive device that determines cardiac output by continuouswave Doppler ultrasound. The aim of this study was to evaluate the accuracy of the USCOM device compared with the PiCCO ( pulse indicated continuous cardiac output) technique on the septic shock patients in Emergency Room and Emergency Intensive Care Unit in Peking Union Medical College Hospital. Methods We conducted a prospective study in Emergency Room and Emergency Intensive Care Unit in Peking Union Medical College Hospital from June lst, 2008 to May 3lst, 2009. Thirty -two patients who were diagnosed as septic shock were recruited in this study. We evaluated the USCOM monitor by

  18. Cardiac Acceleration at the Onset of Exercise : A Potential Parameter for Monitoring Progress During Physical Training in Sports and Rehabilitation

    NARCIS (Netherlands)

    Hettinga, Florentina J.; Monden, Paul G.; van Meeteren, Nico L. U.; Daanen, Hein A. M.

    There is a need for easy-to-use methods to assess training progress in sports and rehabilitation research. The present review investigated whether cardiac acceleration at the onset of physical exercise (HRonset) can be used as a monitoring variable. The digital databases of Scopus and PubMed were

  19. Cardiac acceleration at the onset of exercise: A potential parameter for monitoring progress during physical training in sports and rehabilitation

    NARCIS (Netherlands)

    Hettinga, F.J.; Monden, P.G.; Meeteren, N.L.U. van; Daanen, H.A.M.

    2014-01-01

    There is a need for easy-to-use methods to assess training progress in sports and rehabilitation research. The present review investigated whether cardiac acceleration at the onset of physical exercise (HRonset) can be used as a monitoring variable. The digital databases of Scopus and PubMed were

  20. Cardiac Acceleration at the Onset of Exercise : A Potential Parameter for Monitoring Progress During Physical Training in Sports and Rehabilitation

    NARCIS (Netherlands)

    Hettinga, Florentina J.; Monden, Paul G.; van Meeteren, Nico L. U.; Daanen, Hein A. M.

    2014-01-01

    There is a need for easy-to-use methods to assess training progress in sports and rehabilitation research. The present review investigated whether cardiac acceleration at the onset of physical exercise (HRonset) can be used as a monitoring variable. The digital databases of Scopus and PubMed were se

  1. Methods and apparatus for determining cardiac output

    Science.gov (United States)

    Cohen, Richard J. (Inventor); Mukkamala, Ramakrishna (Inventor); Sherman, Derin A. (Inventor)

    2010-01-01

    The present invention provides methods and apparatus for determining a dynamical property of the systemic or pulmonary arterial tree using long time scale information, i.e., information obtained from measurements over time scales greater than a single cardiac cycle. In one aspect, the invention provides a method and apparatus for monitoring cardiac output (CO) from a single blood pressure signal measurement obtained at any site in the systemic or pulmonary arterial tree or from any related measurement including, for example, fingertip photoplethysmography.According to the method the time constant of the arterial tree, defined to be the product of the total peripheral resistance (TPR) and the nearly constant arterial compliance, is determined by analyzing the long time scale variations (greater than a single cardiac cycle) in any of these blood pressure signals. Then, according to Ohm's law, a value proportional to CO may be determined from the ratio of the blood pressure signal to the estimated time constant. The proportional CO values derived from this method may be calibrated to absolute CO, if desired, with a single, absolute measure of CO (e.g., thermodilution). The present invention may be applied to invasive radial arterial blood pressure or pulmonary arterial blood pressure signals which are routinely measured in intensive care units and surgical suites or to noninvasively measured peripheral arterial blood pressure signals or related noninvasively measured signals in order to facilitate the clinical monitoring of CO as well as TPR.

  2. Development of a fluorescence-based method for monitoring glucose catabolism and its potential use in a biomass hydrolysis assay

    Directory of Open Access Journals (Sweden)

    Anex Robert P

    2008-11-01

    Full Text Available Abstract Background The availability and low cost of lignocellulosic biomass has caused tremendous interest in the bioconversion of this feedstock into liquid fuels. One measure of the economic viability of the bioconversion process is the ease with which a particular feedstock is hydrolyzed and fermented. Because monitoring the analytes in hydrolysis and fermentation experiments is time consuming, the objective of this study was to develop a rapid fluorescence-based method to monitor sugar production during biomass hydrolysis, and to demonstrate its application in monitoring corn stover hydrolysis. Results Hydrolytic enzymes were used in conjunction with Escherichia coli strain CA8404 (a hexose and pentose-consuming strain, modified to produce green fluorescent protein (GFP. The combination of hydrolytic enzymes and a sugar-consuming organism minimizes feedback inhibition of the hydrolytic enzymes. We observed that culture growth rate as measured by change in culture turbidity is proportional to GFP fluorescence and total growth and growth rate depends upon how much sugar is present at inoculation. Furthermore, it was possible to monitor the course of enzymatic hydrolysis in near real-time, though there are instrumentation challenges in doing this. Conclusion We found that instantaneous fluorescence is proportional to the bacterial growth rate. As growth rate is limited by the availability of sugar, the integral of fluorescence is proportional to the amount of sugar consumed by the microbe. We demonstrate that corn stover varieties can be differentiated based on sugar yields in enzymatic hydrolysis reactions using post-hydrolysis fluorescence measurements. Also, it may be possible to monitor fluorescence in real-time during hydrolysis to compare different hydrolysis protocols.

  3. Microbial Monitoring of Common Opportunistic Pathogens by Comparing Multiple Real-Time PCR Platforms for Potential Space Applications

    Science.gov (United States)

    Oubre, Cherie M.; Birmele, Michele N.; Castro, Victoria A.; Venkateswaran, Kasthuri J.; Vaishampayan, Parag A.; Jones, Kathy U.; Singhal, Adesh; Johnston, Angela S.; Roman, Monserrate C.; Ozbolt, Tamra A.; Jett, Daniel X.; Roberts, Michael S.; Ott, C. Mark

    2013-01-01

    Because the International Space Station is a closed environment with rotations of astronauts and equipment that each introduce their own microbial flora, it is necessary to monitor the air, surfaces, and water for microbial contamination. Current microbial monitoring includes labor- and time-intensive methods to enumerate total bacterial and fungal cells, with limited characterization, during in-flight testing. Although this culture-based method is sufficient for monitoring the International Space Station, on future long-duration missions more detailed characterization will need to be performed during flight, as sample return and ground characterization may not be available. At a workshop held in 2011 at NASA's Johnson Space Center to discuss alternative methodologies and technologies suitable for microbial monitoring for these long-term exploration missions, molecular-based methodologies such as polymerase chain reaction (PCR) were recommended. In response, a multi-center (Marshall Space Flight Center, Johnson Space Center, Jet Propulsion Laboratory, and Kennedy Space Center) collaborative research effort was initiated to explore novel commercial-off-the-shelf hardware options for space flight environmental monitoring. The goal was to evaluate quantitative or semi-quantitative PCR approaches for low-cost in-flight rapid identification of microorganisms that could affect crew safety. The initial phase of this project identified commercially available platforms that could be minimally modified to perform nominally in microgravity. This phase was followed by proof-of-concept testing of the highest qualifying candidates with a universally available challenge organism, Salmonella enterica. The analysis identified two technologies that were able to perform sample-to-answer testing with initial cell sample concentrations between 50 and 400 cells. In addition, the commercial systems were evaluated for initial flight safety and readiness.

  4. Invasive and non-invasive methods for cardiac output measurement

    Directory of Open Access Journals (Sweden)

    Lavdaniti M.

    2008-01-01

    Full Text Available The hemodynamic status monitoring of high-risk surgical patients and critically ill patients inIntensive Care Units is one of the main objectives of their therapeutic management. Cardiac output is one of the mostimportant parameters for cardiac function monitoring, providing an estimate of whole body perfusion oxygen deliveryand allowing for an understanding of the causes of high blood pressure. The purpose of the present review is thedescription of cardiac output measurement methods as presented in the international literature. The articles documentthat there are many methods of monitoring the hemodynamic status of patients, both invasive and non-invasive, themost popular of which is thermodilution. The invasive methods are the Fick method and thermodilution, whereasthe non-invasive methods are oeshophaegeal Doppler, transoesophageal echocardiography, lithium dilution, pulsecontour, partial CO2 rebreathing and thoracic electrical bioimpedance. All of them have their advantages and disadvantages,but thermodilution is the golden standard for critical patients, although it does entail many risks. The idealsystem for cardiac output monitoring would be non-invasive, easy to use, reliable and compatible in patients. A numberof research studies have been carried out in clinical care settings, by nurses as well as other health professionals, for thepurpose of finding a method of measurement that would have the least disadvantages. Nevertheless, the thermodilutiontechnique remains the most common approach in use today.

  5. Novel wireless health monitor with acupuncture bio-potentials obtained by using a replaceable salt-water-wetted foam-rubber cushions on RFID-tag.

    Science.gov (United States)

    Lin, Jium-Ming; Lu, Hung-Han; Lin, Cheng-Hung

    2014-01-01

    This paper proposes a bio-potential measurement apparatus including a wireless device for transmitting acupuncture bio-potential information to a remote control station for health conditions analysis and monitor. The key technology of this system is to make replaceable foam-rubber cushions, double-side conducting tapes, chip and antenna on the radio frequency identification (RFID) tag. The foam-rubber cushions can be wetted with salt-water and contact with the acupuncture points to reduce contact resistance. Besides, the double-side conducting tapes are applied to fix foam-rubber cushions. Thus, one can peel the used cushions or tapes away and supply new ones quickly. Since the tag is a flexible plastic substrate, it is easy to deploy on the skin. Besides, the amplifier made by CMOS technology on RFID chip could amplify the signals to improve S/N ratio and impedance matching. Thus, cloud server can wirelessly monitor the health conditions. An example shows that the proposed system can be used as a wireless health condition monitor, the numerical method and the criteria are given to analyze eleven bio-potentials for the important acupunctures of eleven meridians on a person's hands and legs. Then a professional doctor can know the performance of an individual and the cross-linking effects of the organs.

  6. A global condition monitoring system for wind turbines

    DEFF Research Database (Denmark)

    Schlechtingen, Meik

    , which bear the potential to support plant owners reducing turbine downtime and lowering costs. In this research a global condition monitoring system is proposed, which provides a platform to take advantage of the different information sources available to operators. One of the most common sources...... the output signal is entirely reconstructed by using other correlated signals. Benefits in fault visibility and lead-time to failure estimatesare observed. A very important signal to monitor contained in the SCADA data is the wind turbine power output. The power output has a direct influence on the revenue...... with false brinelling. Finally, a global fuzzy expert system is developed giving the possibility of linking all available information in terms of fuzzy logic rules. It is important to highlight that this research is based on real measured data coming from two wind power plants with turbines of a different...

  7. Input and output budgets of radiocesium concerning the forest floor in the mountain forest of Fukushima released from the TEPCO's Fukushima Dai-ichi nuclear power plant accident.

    Science.gov (United States)

    Niizato, Tadafumi; Abe, Hironobu; Mitachi, Katsuaki; Sasaki, Yoshito; Ishii, Yasuo; Watanabe, Takayoshi

    2016-09-01

    Estimations of radiocesium input and output concerning the forest floor within a mountain forest region have been conducted in the north and central part of the Abukuma Mountains of Fukushima, northeast Japan, after a 2-3 year period following the TEPCO Fukushima Dai-ichi nuclear power plant accident. The radiocesium input and output associated with surface washoff, throughfall, stemflow, and litterfall processes at experimental plots installed on the forest floor of evergreen Japanese cedars and deciduous Konara oaks have been monitored. Despite the high output potential in the mountainous forest of Fukushima, the results at both monitoring locations show the radiocesium input to be 4-50 times higher than the output during the summer monsoon in Fukushima. These results indicate that the radiocesium tends to be preserved in the forest ecosystem due to extremely low output ratios (0.05%-0.19%). Thus, the associated fluxes throughout the circulation process are key issues for the projecting the environmental fate of the radiocesium levels, along with the subsequent reconstruction of life emphasized within the setting.

  8. Magnetically insulated baffled probe for real-time monitoring of equilibrium and fluctuating values of space potentials, electron and ion temperatures, and densities.

    Science.gov (United States)

    Demidov, V I; Koepke, M E; Raitses, Y

    2010-10-01

    By restricting the electron-collection area of a cold Langmuir probe compared to the ion-collection area, the probe floating potential can become equal to the space potential, and thus conveniently monitored, rather than to a value shifted from the space potential by an electron-temperature-dependent offset, i.e., the case with an equal-collection-area probe. This design goal is achieved by combining an ambient magnetic field in the plasma with baffles, or shields, on the probe, resulting in species-selective magnetic insulation of the probe collection area. This permits the elimination of electron current to the probe by further adjustment of magnetic insulation which results in an ion-temperature-dependent offset when the probe is electrically floating. Subtracting the floating potential of two magnetically insulated baffled probes, each with a different degree of magnetic insulation, enables the electron or ion temperature to be measured in real time.

  9. The Effects of Acute Dopamine Precursor Depletion on the Cognitive Control Functions of Performance Monitoring and Conflict Processing: An Event-Related Potential (ERP) Study

    Science.gov (United States)

    Primosch, Mark; Leyton, Marco; Steffensen, Scott C.

    2015-01-01

    Studies using medications and psychiatric populations implicate dopamine in cognitive control and performance monitoring processes. However, side effects associated with medication or studying psychiatric groups may confound the relationship between dopamine and cognitive control. To circumvent such possibilities, we utilized a randomized, double-blind, placebo-controlled, within-subjects design wherein participants were administered a nutritionally-balanced amino acid mixture (BAL) and an amino acid mixture deficient in the dopamine precursors tyrosine (TYR) and phenylalanine (PHE) on two separate occasions. Order of sessions was randomly assigned. Cognitive control and performance monitoring were assessed using response times (RT), error rates, the N450, an event-related potential (ERP) index of conflict monitoring, the conflict slow potential (conflict SP), an ERP index of conflict resolution, and the error-related negativity (ERN) and error positivity (Pe), ERPs associated with performance monitoring. Participants were twelve males who completed a Stroop color-word task while ERPs were collected four hours following acute PHE and TYR depletion (APTD) or balanced (BAL) mixture ingestion in two separate sessions. N450 and conflict SP ERP amplitudes significantly differentiated congruent from incongruent trials, but did not differ as a function of APTD or BAL mixture ingestion. Similarly, ERN and Pe amplitudes showed significant differences between error and correct trials that were not different between APTD and BAL conditions. Findings indicate that acute dopamine precursor depletion does not significantly alter cognitive control and performance monitoring ERPs. Current results do not preclude the role of dopamine in these processes, but suggest that multiple methods for dopamine-related hypothesis testing are needed. PMID:26492082

  10. Single-InN-Nanowire Nanogenerator with Upto 1 V Output Voltage

    KAUST Repository

    Huang, Chi-Te

    2010-07-30

    Piezoelectric potential of a InN nanowire (NW) growing along [011̄0] can be positive, negative, and zero depending on the direction of the applied transverse force. By measuring the output voltage of a InN-NW-based nanogenerator, about 40% to 55% of output voltages are within the range of ?1 and ?20 mV, and 25% to 30% of output voltages would exceed ?100 mV. Some output voltages could reach the magnitude of ?1000 mV, showing its great potential for fabricating high-output nanogenerators. © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  11. Learning about a shift in trend output: implications for monetary policy and inflation

    OpenAIRE

    Lansing, Kevin J.

    2000-01-01

    This paper develops a small forward-looking macroeconomic model where the Federal Reserve estimates the level of potential output in real time by running a regression on past output data. The Fed's perceived output gap is used as an input to the monetary policy rule while the true output gap influences aggregate demand and inflation. I investigate the consequences of two postulated shifts in the growth rate of U.S. potential output: the first occurs in the early-1970s and the second in the mi...

  12. Random output and hospital performance.

    Science.gov (United States)

    Barros, Pedro Pita

    2003-11-01

    Many countries are under pressure to reform health care financing and delivery. Hospital care is one part of the health system that is under scrutiny. Private management initiatives are a possible way to increase efficiency in health care delivery. This motivates the interest in developing methodologies to assess hospital performance, recognizing hospitals as a different sort of firm. We present a simple way to describe hospital production: hospital output as a change in the distribution of survival probabilities. This output definition allows us to separate hospital production from patients' characteristics. The notion of "better performance" has a precise meaning: (first-order) stochastic dominance of a distribution of survival probabilities over another distribution. As an illustration, we compare, for an important DRG, private and public management and find that private management performs better, mainly in the range of high-survival probabilities. The measured performance difference cannot be attributed to input prices or to economies of scale and/or scope. It reflects pure technological and organisational differences.

  13. Potentials, Limitations and Applications of long-term and mobile ad-hoc Wireless Sensor Networks for Environmental Monitoring

    Science.gov (United States)

    Bumberger, Jan; Mollenhauer, Hannes; Lapteva, Yulia; Hutschenreuther, Tino; Toepfer, Hannes; Dietrich, Peter

    2014-05-01

    To characterize environmental systems it is necessary to identify and describe processes with suitable methods. Environmental systems are often characterized by their high heterogeneity, so individual measurements for their complete representation are often not sufficient. The application of wireless sensor networks in terrestrial and aquatic ecosystems offer significant benefits as a better consideration of the local test conditions becomes possible. This can be essential for the monitoring of heterogeneous environmental systems. Significant advantages in the application of mobile ad-hoc wireless sensor networks are their self-organizing behavior, resulting in a major reduction in installation and operation costs and time. In addition, a point measurement with a sensor is significantly improved by measuring at several points. It is also possible to perform analog and digital signal processing and computation on the basis of the measured data close to the sensor. Hence, a significant reduction of the data to be transmitted can be achieved which leads to a better energy management of sensor nodes. Furthermore, their localization via satellite, the miniaturization of the nodes and long-term energy self-sufficiency are current topics under investigation. The possibilities and limitations of the applicability of wireless sensor networks for long-term and mobile environmental monitoring are presented. A concepts and realization example are given in the field of micrometeorology and soil parameters for the interaction of biotic and abiotic processes .This long term monitoring is part of the Global Change Experimental Facility (GCEF), a large field-based experimental platform to assess the effects of climate change on ecosystem functions and processes under different land-use scenarios. Furthermore a mobile ad-hoc sensor network is presented for the monitoring of water induced mass wasting processes.

  14. Low-cost Photoacoustic-based Measurement System for Carbon Dioxide Fluxes with the Potential for large-scale Monitoring

    Science.gov (United States)

    Scholz, L. T.; Bierer, B.; Ortiz Perez, A.; Woellenstein, J.; Sachs, T.; Palzer, S.

    2016-12-01

    The determination of carbon dioxide (CO2) fluxes between ecosystems and the atmosphere is crucial for understanding ecological processes on regional and global scales. High quality data sets with full uncertainty estimates are needed to evaluate model simulations. However, current flux monitoring techniques are unsuitable to provide reliable data of a large area at both a detailed level and an appropriate resolution, at best in combination with a high sampling rate. Currently used sensing technologies, such as non-dispersive infrared (NDIR) gas analyzers, cannot be deployed in large numbers to provide high spatial resolution due to their costs and complex maintenance requirements. Here, we propose a novel CO2 measurement system, whose gas sensing unit is made up of low-cost, low-power consuming components only, such as an IR-LED and a photoacoustic detector. The sensor offers a resolution of costs favor the manufacturing in large quantities. This allows the operation of multiple sensors at a reasonable price and thus provides concentration measurements at any desired spatial coverage and at high temporal resolution. With appropriate 3D configuration of the units, vertical and horizontal fluxes can be determined. By applying a closely meshed wireless sensor network, inhomogeneities as well as CO2 sources and sinks in the lower atmosphere can be monitored. In combination with sensors for temperature, pressure and humidity, our sensor paves the way towards the reliable and extensive monitoring of ecosystem-atmosphere exchange rates. The technique can also be easily adapted to other relevant greenhouse gases.

  15. Nutritional and fluid requirements: high-output stomas.

    Science.gov (United States)

    Medlin, Sophie

    Based on the current available evidence, this article explores the nutritional management of those with a high-output stoma. The main alterations required to the intake of patients with a high-output stoma include the use of an oral rehydration solution to ensure optimum absorption of fluid and sodium, and a high-calorie, high-protein diet, with the aim of optimizing nutritional status. Diet advice should be delivered by a dietitian with experience in managing these complex patients. Monitoring of electrolytes and micronutrients is essential, and long-term follow up from a multidisciplinary nutrition support team is invaluable in coordinating this. Patients with high-output stomas can enjoy good quality of life and long-term health if their condition is managed effectively by a well-organized multidisciplinary team.

  16. Integration of TMVA Output into Jupyter notebooks

    CERN Document Server

    Saliji, Albulena

    2016-01-01

    The purpose of this report is to describe the work that I have been doing during these past eight weeks as a Summer Student at CERN. The task which was assigned to me had to do with the integration of TMVA Output into Jupyter notebooks. In order to integrate the TMVA Output into the Jupyter notebook, first, improvement of the TMVA Output in the terminal was required. Once the output was improved, it needed to be transformed into HTML output and at the end it would be possible to integrate that output into the Jupyter notebook.

  17. Kredsløbsmonitorering af kritisk syge patienter med "pulse contour cardiac output"-systemet

    DEFF Research Database (Denmark)

    Afshari, Arash; Perner, Anders; Bonde, Jan

    2006-01-01

    The Pulse Contour Cardiac Output (PiCCO) monitoring system measures cardiac output with high precision and accuracy. The system may replace the pulmonary artery catheter in most critically ill patients because the rate of serious complications may be lower. Whether the use of dynamic or static fl...... fluid monitoring by PiCCO will result in better outcomes should be assessed by studies using clinically relevant end points....

  18. Intraoperative facial motor evoked potentials monitoring with transcranial electrical stimulation for preservation of facial nerve function in patients with large acoustic neuroma

    Institute of Scientific and Technical Information of China (English)

    LIU Bai-yun; TIAN Yong-ji; LIU Wen; LIU Shu-ling; QIAO Hui; ZHANG Jun-ting; JIA Gui-jun

    2007-01-01

    Background Although various monitoring techniques have been used routinely in the treatment of the lesions in the skull base, iatrogenic facial paresis or paralysis remains a significant clinical problem. The aim of this study was to investigate the effect of intraoperative facial motor evoked potentials monitoring with transcranial electrical stimulation on preservation of facial nerve function.Method From January to November 2005, 19 patients with large acoustic neuroma were treated using intraoperative facial motor evoked potentials monitoring with transcranial electrical stimulation (TCEMEP) for preservation of facial nerve function. The relationship between the decrease of MEP amplitude after tumor removal and the postoperative function of the facial nerve was analyzed.Results MEP amplitude decreased more than 75% in 11 patients, of which 6 presented significant facial paralysis (H-B grade 3), and 5 had mild facial paralysis (H-B grade 2). In the other 8 patients, whose MEP amplitude decreased less than 75%, 1 experienced significant facial paralysis, 5 had mild facial paralysis, and 2 were normal.Conclusions Intraoperative TCEMEP can be used to predict postoperative function of the facial nerve. The decreased MEP amplitude above 75 % is an alarm point for possible severe facial paralysis.

  19. Intraoperative monitoring during decompression of the spinal cord and spinal nerves using transcranial motor-evoked potentials: The law of twenty percent.

    Science.gov (United States)

    Tanaka, Satoshi; Hirao, Jun; Oka, Hidehiro; Akimoto, Jiro; Takanashi, Junko; Yamada, Junichi

    2015-09-01

    Motor-evoked potential (MEP) monitoring was performed during 196 consecutive spinal (79 cervical and 117 lumbar) surgeries for the decompression of compressive spinal and spinal nerve diseases. MEP monitoring in spinal surgery has been considered sensitive to predict postoperative neurological recovery. In this series, transcranial stimulation consisted of trains of five pulses at a constant voltage (200-600 V). For the normalization of MEP, we recorded compound muscle action potentials (CMAP) after peripheral nerve stimulation, usually on the median nerve at the wrist 2 seconds before or after each transcranial stimulation of the motor area, for all operations. The sensitivity and specificity of MEP monitoring was 100% and 97.4%, respectively, or 96.9% with or without CMAP compensation (if the threshold of postoperative motor palsy was defined as 20% relative amplitude rate [RAR]). The mean RAR after CMAP normalization, of the most affected muscle in the patient group with excellent postoperative results (recovery rate of a Japan Orthopedic Association score of more than 50%) was significantly higher than that in the other groups (p=0.0224). All patients with an amplitude increase rate (AIR) with CMAP normalization of more than 20% achieved neurological recovery postoperatively. Our results suggest that if the RAR is more than 20%, postoperative motor palsy can be avoided in spinal surgery. If the AIR with normalization by CMAP after peripheral nerve stimulation is more than 20%, neurological recovery can be expected in spinal surgery.

  20. The Potential of Various Living Tissues for Monitoring Clenbuterol Abuse in Food-Producing Chinese Simmental Beef Cattle.

    Science.gov (United States)

    Li, Lijun; Tang, Chaohua; Zhang, Junmin; Zhao, Qingyu; Zhang, Kai

    2016-01-01

    We aimed to evaluate whether living tissues such as urine, plasma and hair were suitable for monitoring clenbuterol (CL) abuse after its subchronic administration of a growth-promoting dose to the Chinese Simmental beef cattle. Eight male, white and red pied Chinese Simmental beef cattle were involved in the experiment, and the CL dose was 16 µg/kg BW/day. Liquid chromatography tandem mass spectrometry (LC-MS-MS) was used to determine CL residues in different tissues, and the addition of D9-clenbuterol internal standard was applied to increase determination accuracy. The recovery of plasma, urine, hair and in vivo tissues was 88.5-114.2, 83.9-114.3, 88.6-116.9 and 85.3-121.7%, respectively. The results showed that CL residue concentrations in the plasma, on Days 14 after withdrawal and later, were lower than the limit of detection (LOD) (0.06 ng/mL) and CL residue in urine was lower than LOD (0.16 ng/mL) 42 days after treatment. CL significantly accumulated in the white and red hair and maintained more than 7.19 ± 2.19 pg/mg within the early withdrawal period of 70 days. A large number of CL were determined in all tested biological tissues, in which residues were higher than the maximum residue limits (MRLs) after dietary administration of CL for 21 days and pre-slaughter withdrawal period of ∼6 h. A particular concern is the slow depletion of residues of CL in some tissues like gluteus and liver still exceeding theirs MRLs, respectively, on Days 14 or 28 days after withdrawal. Our study indicated that plasma and urine could be available for monitoring CL abuse only within a short period of time. However, hair (including light-pigmented) as a target matrix can be selected to perform the long-period monitor of CL.

  1. Output regulation problem for discrete-time linear time-delay systems by output feedback control

    Institute of Scientific and Technical Information of China (English)

    Yamin YAN; Jie HUANG

    2016-01-01

    In this paper, we study the output regulation problem of discrete linear time-delay systems by output feedback control. We have established some results parallel to those for the output regulation problem of continuous linear time-delay systems.

  2. Judicial Influence on Policy Outputs?

    DEFF Research Database (Denmark)

    Martinsen, Dorte Sindbjerg

    2015-01-01

    The ability of courts to generate political change has long been debated in national, comparative, and international politics. In the examination of the interaction between judicial and legislative politics, scholars have disagreed on the degree of judicial power and the ability of politics...... to override unwanted jurisprudence. In this debate, the Court of Justice of the European Union (CJEU) has become famous for its central and occasionally controversial role in European integration. This article examines to what extent and under which conditions judicial decisions influence European Union (EU......) social policy outputs. A taxonomy of judicial influence is constructed, and expectations of institutional and political conditions on judicial influence are presented. The analysis draws on an extensive novel data set and examines judicial influence on EU social policies over time, that is, between 1958...

  3. Cooperative Monitoring Center Occasional Paper/16: The Potential of Technology for the Control of Small Weapons: Applications in Developing Countries

    Energy Technology Data Exchange (ETDEWEB)

    ALTMANN, JURGEN

    2000-07-01

    For improving the control of small arms, technology provides many possibilities. Present and future technical means are described in several areas. With the help of sensors deployed on the ground or on board aircraft, larger areas can be monitored. Using tags, seals, and locks, important objects and installations can be safeguarded better. With modern data processing and communication systems, more information can be available, and it can be more speedily processed. Together with navigation and transport equipment, action can be taken faster and at greater range. Particular considerations are presented for cargo control at roads, seaports, and airports, for monitoring designated lines, and for the control of legal arms. By starting at a modest level, costs can be kept low, which would aid developing countries. From the menu of technologies available, systems need to be designed for the intended application and with an understanding of the local conditions. It is recommended that states start with short-term steps, such as acquiring more and better radio transceivers, vehicles, small aircraft, and personal computers. For the medium term, states should begin with experiments and field testing of technologies such as tags, sensors, and digital communication equipment.

  4. Remote Monitoring of the Heart Condition of Athletes by Measuring the Cardiac Action Potential Propagation Time Using a Wireless Sensor Network

    Directory of Open Access Journals (Sweden)

    Amang Sudarsono

    2016-04-01

    Full Text Available Highly performing athletes are susceptible to cardiac damage of several kinds which may be irreversible. The monitoring of heart rate and ECG waveforms from such subjects by wireless sensor networks has been reported in health and sports care documents. However, a more decisive parameter for instant to instant changes would be the time of Cardiac Action Potential Propagation. This time, which can be between 15-20 ms would shoot suddenly in acute stress in highly performing athletes for short durations. Repeated incidents of such rising values will tend to cause irreversible damage to the heart. We developed the technique of measuring this time and reporting it through a wireless sensor network to monitoring station.

  5. Variance estimation of modal parameters from output-only and input/output subspace-based system identification

    Science.gov (United States)

    Mellinger, Philippe; Döhler, Michael; Mevel, Laurent

    2016-09-01

    An important step in the operational modal analysis of a structure is to infer on its dynamic behavior through its modal parameters. They can be estimated by various modal identification algorithms that fit a theoretical model to measured data. When output-only data is available, i.e. measured responses of the structure, frequencies, damping ratios and mode shapes can be identified assuming that ambient sources like wind or traffic excite the system sufficiently. When also input data is available, i.e. signals used to excite the structure, input/output identification algorithms are used. The use of input information usually provides better modal estimates in a desired frequency range. While the identification of the modal mass is not considered in this paper, we focus on the estimation of the frequencies, damping ratios and mode shapes, relevant for example for modal analysis during in-flight monitoring of aircrafts. When identifying the modal parameters from noisy measurement data, the information on their uncertainty is most relevant. In this paper, new variance computation schemes for modal parameters are developed for four subspace algorithms, including output-only and input/output methods, as well as data-driven and covariance-driven methods. For the input/output methods, the known inputs are considered as realizations of a stochastic process. Based on Monte Carlo validations, the quality of identification, accuracy of variance estimations and sensor noise robustness are discussed. Finally these algorithms are applied on real measured data obtained during vibrations tests of an aircraft.

  6. A Method for Monitoring Deposition at a Solid Cathode in an Electrorefiner for a Two-Species System Using Electrode Potentials

    Energy Technology Data Exchange (ETDEWEB)

    D.S. Rappleye; M.-S. Yim; M.F. Simpson; R.M. Cumberland

    2013-10-01

    Currently, process monitoring of spent nuclear fuel electrorefining relies upon sampling and destructive analysis methods coupled with extrapolative thermodynamic process models for non-interrupted operations. Corrections to those models are performed infrequently, jeopardizing both the control of the process and safeguarding of nuclear material. Furthermore, the timeliness of obtaining the results is inadequate for application of international safeguards protocol. Alternatively, a system that dynamically utilizes electrical data such as electrode potentials and cell current can hypothetically be used to achieve real-time process monitoring and more robust control as well as improved safeguards. Efforts to develop an advanced model of the electrorefiner to date have focused on a forward modeling approach by using feed and salt compositions to determine the product composition, cell current and electrode potential response. Alternatively, an inverse model was developed, and reported here, to predict the product deposition rates on a cathode using the cell current, cathode potential, and fundamental relations of electrochemistry. The model was applied to the following cases: pure uranium deposition, co-deposition of uranium and plutonium, and co-deposition of uranium and zirconium. The deposition rates predicted by the inverse model were compared to those of a forward model, ERAD.

  7. A Method for Monitoring Deposition at a Solid Cathode in an Electrorefiner for a Two-Species System Using Electrode Potentials

    Energy Technology Data Exchange (ETDEWEB)

    D.S. Rappleye; M.-S. Yim; M.F. Simpson; R.M. Cumberland

    2013-10-01

    Currently, process monitoring of spent nuclear fuel electrorefining relies upon sampling and destructive analysis methods coupled with extrapolative thermodynamic process models for non-interrupted operations. Corrections to those models are performed infrequently, jeopardizing both the control of the process and safeguarding of nuclear material. Furthermore, the timeliness of obtaining the results is inadequate for application of international safeguards protocol. Alternatively, a system that dynamically utilizes electrical data such as electrode potentials and cell current can hypothetically be used to achieve real-time process monitoring and more robust control as well as improved safeguards. Efforts to develop an advanced model of the electrorefiner to date have focused on a forward modeling approach by using feed and salt compositions to determine the product composition, cell current and electrode potential response. Alternatively, an inverse model was developed, and reported here, to predict the product deposition rates on a cathode using the cell current, cathode potential, and fundamental relations of electrochemistry. The model was applied to the following cases: pure uranium deposition, co-deposition of uranium and plutonium, and co-deposition of uranium and zirconium. The deposition rates predicted by the inverse model were compared to those of a forward model, ERAD.

  8. [Diagnostic potential of the lower-body negative pressure test in medical monitoring during extended space flights].

    Science.gov (United States)

    Aslferova, I V; Turchaninova, V F; Golubchikova, Z A; Krivolapov, V V; Khorosheva, E G

    2007-01-01

    To put into service the diagnostic and prognostic capabilities of the lower body negative pressure test (LBNP) during extended space flights, cardiovascular reactions associated with various levels of test tolerance were analyzed and compared. The article gives account of 60 tests performed by 44 cosmonauts 33 to 53 years of age during 59- to 415-d flights. In 36 tests tolerance was good and in 24 - satisfactory. Medical evaluation was fulfilled using GaMMa-1M, an onboard multifunctional medical monitoring system. Dynamics of ECG, blood pressure, stroke and minute volumes, pulse filling, and vertebral-basilar tone exhibited some specific traits that mirrored LBNP tolerance. Established were diagnostically implicative values in the course of pressure drop. Evidence was obtained that during the test and ensuing data analysis consideration should be given as to the span of changes of each parameter, so the time of their initiation, and dynamics.

  9. Potential of the future thermal infrared space-borne sensor IASI-NG to monitor lower tropospheric ozone

    Directory of Open Access Journals (Sweden)

    P. Sellitto

    2012-09-01

    Full Text Available The lower tropospheric (LT ozone concentration is a key factor for air quality (AQ. Observing efficiently LT ozone from space is crucial to monitor and better understand pollution phenomena occurring from inter-continental to local scales, and that have a proven noxious effect on the human health and the biosphere. The Infrared Atmospheric Sounder Interferometer (IASI flies on MetOp-A spacecraft and is planned to be launched in the next future as part of the other MetOp modules, i.e. MetOp-B and C. IASI has demonstrated to have the capability to single out the LT ozone signal only at favourable conditions, i.e. in presence of high thermal contrast scenarios. New generation satellite instruments are being designed to address several pressing geophysical issues, including a better observation capability of LT ozone. IASI-NG (New Generation, now having reached the accomplishment of design phase-A for launch in the 2020 timeframe as part of the EPS-SG (EUMETSAT Polar System-Second Generation, formerly post-EPS mission, may render feasible a better observation of AQ in terms of LT ozone. To evaluate the added-value brought by IASI-NG in this context, we developed a pseudo-observation simulator, including a direct simulator of thermal infrared spectra and a full inversion scheme to retrieve ozone concentration profiles. We produced one month (August 2009 of tropospheric ozone pseudo-observations based on both IASI and IASI-NG instrumental configurations. We compared the pseudo-observations and we found a clear improvement of LT ozone (up to 6 km altitude pseudo-observations quality for IASI-NG. The estimated total error is expected to be more than 35% smaller at 5 km, and 20% smaller for the LT ozone column. The total error on the LT ozone column is, on average, lower than 10% for IASI-NG. IASI-NG is expected to have a significantly better vertical sensitivity (monthly average degrees of freedom surface-6 km of 0.70 and to be sensitive at lower

  10. Monitoring of saline tracer movement with vertically distributed self-potential measurements at the HOBE agricultural test site, Voulund, Denmark

    CERN Document Server

    Jougnot, Damien; Haarder, Eline B; Looms, Majken C

    2015-01-01

    The self-potential (SP) method is sensitive to water fluxes in saturated and partially saturated porous media, such as those associated with rainwater infiltration and groundwater recharge. We present a field-based study at the Voulund agricultural test site, Denmark, that is, to the best of our knowledge, the first to focus on the vertical self-potential distribution prior to and during a saline tracer test. A coupled hydrogeophysical modeling framework is used to simulate the SP response to precipitation and saline tracer infiltration. A layered hydrological model is first obtained by inverting dielectric and matric potential data. The resulting model that compares favorably with electrical resistance tomography models is subsequently used to predict the SP response. The electrokinetic contribution (caused by water fluxes in a charged porous soil) is modeled by an effective excess charge approach that considers both water saturation and pore water salinity. Our results suggest that the effective excess char...

  11. The TNF-α antagonist etanercept reverses age-related decreases in colonic SERT expression and faecal output in mice

    Science.gov (United States)

    Patel, Bhavik Anil; Fidalgo, Sara; Wang, Chunfang; Parmar, Leena; Mandona, Kasonde; Panossian, Annabelle; Flint, Melanie S.; Ranson, Richard N.; Saffrey, M. Jill; Yeoman, Mark S.

    2017-01-01

    Treatment for chronic constipation in older people is challenging and the condition has a major impact on quality of life. A lack of understanding about the causes of this condition has hampered the development of effective treatments. 5-HT is an important pro-kinetic agent in the colon. We examined whether alterations in colonic 5-HT signalling underlie age–related changes in faecal output in mice and whether these changes were due to an increase in TNF-α. Components of the 5-HT signalling system (5-HT, 5-HIAA, SERT) and TNF-α expression were examined in the distal colon of 3, 12, 18 and 24-month old mice and faecal output and water content monitored under control conditions and following the administration of etanercept (TNF-α inhibitor; 1 mg Kg−1). Faecal output and water content were reduced in aged animals. Age increased mucosal 5-HT availability and TNF-α expression and decreased mucosal SERT expression and 5-HIAA. Etanercept treatment of old mice reversed these changes, suggesting that age-related changes in TNFα expression are an important regulator of mucosal 5-HT signalling and pellet output and water content in old mice. These data point to “anti-TNFα” drugs as potential treatments for age-related chronic constipation. PMID:28198447

  12. On the relationship between the tree and its environment, based on electrical potential difference monitoring on trunk of trees

    Science.gov (United States)

    Koppan, A.; Fenyvesi, A.; Szarka, L.; Wesztergom, V.

    2002-05-01

    Electrical potential differences (EPD) in the trunk of a Turkey oak tree (measured by using non-polarising electrodes deepened in the sap wood) have been continuously recorded in the Geophysical Observatory "Istv n Széchenyi" of the Hungarian Academy of Sciences since 1997. Besides of various geophysical observations, meteorological and direct sap-flow measurements have also been carried out in the observatory. As it was found (Kopp n A., Szarka L., Wesztergom V., 2000: Annual fluctuation in amplitudes of daily variations of electrical signals measured in the trunk of a standing tree. C.R. Acad. Sci. Paris, Life Sciences 323, 559-563), the measured electric potential difference data have a characteristic sinusoidal daily fluctuation, and the intensity of the diurnal variations has a double-peak annual characteristics, which coincides with the life activity maximums of the tree. We have found a remarkable inter-correlation between trunk EPD, water potential of air (derived from meteorological data), and direct sap flow velocity data from a neighboring tree. All these results clearly demonstrate that the sap streaming due to the transpiration and root pressure generates the largest part of measured potential differences. The ratio of the flow velocity of a diluted solution forced through stems and the potential differences was found to be constant (Gindl, W., L”ppert, H.-G., Wimmer, R., 1999: Relationship between streaming potential and sap velocity in Salix alba L. Phyton, 39, 217-224.). On the contrary in our in-vivo experiments the relationship between the measured sap flow velocity and EPD is non-linear, which means that the conductivity (i.e. ion concentration) of the xylem sap itself also has a daily fluctuation.

  13. Monitoring the Recovery of c-Si Modules from Potential-Induced Degradation Using Suns-Voc Curves

    Energy Technology Data Exchange (ETDEWEB)

    Wilterdink, Harrison; Sinton, Ronald; Hacke, Peter; Terwilliger, Kent; Meydbray, Jenya

    2016-11-21

    Potential-induced degradation (PID) has recently been shown as an important failure mode in c-Si modules. We demonstrate the utility of Suns-Voc analysis for measuring shunt effects caused by PID at the module level. Our results show module shunt resistance increasing in step with module power during recovery from the degraded state.

  14. Comparison of bispectral index and composite auditory evoked potential index for monitoring depth of hypnosis in children

    NARCIS (Netherlands)

    H.J.B. van Oud-Alblas; J.W.B. Peters (Jeroen); T.G. de Leeuw (Tom); D. Tibboel (Dick); J. Klein (Jan); F. Weber (Frank)

    2008-01-01

    textabstractBACKGROUND: In pediatric patients, the Bispectral Index (BIS), derived from the electroencephalogram, and the composite A-Line autoregressive index (cAAI), derived from auditory evoked potentials and the electroencephalogram, have been used as measurements of depth of hypnosis during

  15. Comparison of bispectral index and composite auditory evoked potential index for monitoring depth of hypnosis in children

    NARCIS (Netherlands)

    H.J.B. van Oud-Alblas; J.W.B. Peters (Jeroen); T.G. de Leeuw (Tom); D. Tibboel (Dick); J. Klein (Jan); F. Weber (Frank)

    2008-01-01

    textabstractBACKGROUND: In pediatric patients, the Bispectral Index (BIS), derived from the electroencephalogram, and the composite A-Line autoregressive index (cAAI), derived from auditory evoked potentials and the electroencephalogram, have been used as measurements of depth of hypnosis during ane

  16. Reduced pallidal output causes dystonia

    Directory of Open Access Journals (Sweden)

    Atsushi eNambu

    2011-11-01

    Full Text Available Dystonia is a neurological disorder characterized by sustained or repetitive involuntary muscle contractions and abnormal postures. In the present article, we will introduce our recent electrophysiological studies in hyperkinetic transgenic mice generated as a model of DYT1 dystonia and in a human cervical dystonia patient, and discuss the pathophysiology of dystonia on the basis of these electrophysiological findings. Recording of neuronal activity in the awake state of DYT1 dystonia model mice revealed reduced spontaneous activity with bursts and pauses in both internal (GPi and external (GPe segments of the globus pallidus. Electrical stimulation of the primary motor cortex evoked responses composed of excitation and subsequent long-lasting inhibition, the latter of which was never observed in normal mice. In addition, somatotopic arrangements were disorganized in the GPi and GPe of dystonia model mice. In a human cervical dystonia patient, electrical stimulation of the primary motor cortex evoked similar long-lasting inhibition in the GPi and GPe. Thus, reduced GPi output may cause increased thalamic and cortical activity, resulting in the involuntary movements observed in dystonia.

  17. Model output: fact or artefact?

    Science.gov (United States)

    Melsen, Lieke

    2015-04-01

    As a third-year PhD-student, I relatively recently entered the wonderful world of scientific Hydrology. A science that has many pillars that directly impact society, for example with the prediction of hydrological extremes (both floods and drought), climate change, applications in agriculture, nature conservation, drinking water supply, etcetera. Despite its demonstrable societal relevance, hydrology is often seen as a science between two stools. Like Klemeš (1986) stated: "By their academic background, hydrologists are foresters, geographers, electrical engineers, geologists, system analysts, physicists, mathematicians, botanists, and most often civil engineers." Sometimes it seems that the engineering genes are still present in current hydrological sciences, and this results in pragmatic rather than scientific approaches for some of the current problems and challenges we have in hydrology. Here, I refer to the uncertainty in hydrological modelling that is often neglected. For over thirty years, uncertainty in hydrological models has been extensively discussed and studied. But it is not difficult to find peer-reviewed articles in which it is implicitly assumed that model simulations represent the truth rather than a conceptualization of reality. For instance in trend studies, where data is extrapolated 100 years ahead. Of course one can use different forcing datasets to estimate the uncertainty of the input data, but how to prevent that the output is not a model artefact, caused by the model structure? Or how about impact studies, e.g. of a dam impacting river flow. Measurements are often available for the period after dam construction, so models are used to simulate river flow before dam construction. Both are compared in order to qualify the effect of the dam. But on what basis can we tell that the model tells us the truth? Model validation is common nowadays, but validation only (comparing observations with model output) is not sufficient to assume that a

  18. Evaluating the potential for quantitative monitoring of in situ chemical oxidation of aqueous-phase TCE using in-phase and quadrature electrical conductivity

    Science.gov (United States)

    Hort, R. D.; Revil, A.; Munakata-Marr, J.; Mao, D.

    2015-07-01

    Electrical resistivity measurements can potentially be used to remotely monitor fate and transport of ionic oxidants such as permanganate (MnO4-) during in situ chemical oxidation (ISCO) of contaminants like trichloroethene (TCE). Time-lapse two-dimensional bulk conductivity and induced polarization surveys conducted during a sand tank ISCO simulation demonstrated that MnO4- plume movement could be monitored in a qualitative manner using bulk conductivity tomograms, although chargeability was below sensitivity limits. We also examined changes to in-phase and quadrature electrical conductivity resulting from ion injection, MnO2 and Cl- production, and pH change during TCE and humate oxidation by MnO4- in homogeneous aqueous solutions and saturated porous media samples. Data from the homogeneous samples demonstrated that inversion of the sand tank resistivity data using a common Tikhonov regularization approach was insufficient to recover an accurate conductivity distribution within the tank. While changes to in-phase conductivity could be successfully modeled, quadrature conductivity values could not be directly related to TCE oxidation product or MnO4- concentrations at frequencies consistent with field induced polarization surveys, limiting the utility of quadrature conductivity for monitoring ISCO.

  19. [Monitoring of Somatosensory Evoked Potentials during Foramen Magnum Decompression of Chiari Malformation Type I Complicated with Syringomyelia: A Report of Two Cases].

    Science.gov (United States)

    Kadoya, Tatsuo; Takenaka, Ichiro; Kinoshita, Yuki; Shiraishi, Munehiro; Uehara, Hirofumi; Yamamoto, Toshinori; Joyashiki, Takeshi

    2015-03-01

    Few reports exist on anesthetic management for foramen magnum decompression (FMD) of Chiari malformation type I (CM I) complicated with syringomyelia. In two such cases we monitored somatosensory evoked potentials (SEP). Case 1 : A 40-year-old woman presented with occipital headache and nuchal pain for 2 months; numbness and muscular weakness of bilateral upper limbs for a month. Magnetic resonance imaging (MRI) scan showed CM I complicated with syringomyelia. Case 2 : A 32-year-old man presented with numbness and muscular weakness of bilateral upper limbs for 5 months; numbness and muscular weakness of lower limbs for 2 months. MRI scan showed CM I complicated with syringomyelia. They underwent FMD. In both cases, general anesthesia was induced with remifentanil, propofol and rocuronium, and was maintained with oxygen, air, remifentanil and propofol. Moreover, we monitored SEP. Their operative courses were uneventful. In case 1, SEP latency became shorter after FMD. Her preoperative neurologic symptoms disappeared on first postoperative day. In contrast there was no change of SEP latency after FMD in case 2. His preoperative neurologic symptoms showed no change on fifth postoperative day. SEP monitoring may be a useful index for prediction of early recovery of neurologic symptoms after FMD.

  20. An alpha-synuclein MRM assay with diagnostic potential for Parkinson's disease and monitoring disease progression

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Li [Department of Pathology, University of Washington, Seattle WA USA; Stewart, Tessandra [Department of Pathology, University of Washington, Seattle WA USA; Shi, Min [Department of Pathology, University of Washington, Seattle WA USA; Pottiez, Gwenael [Department of Pathology, University of Washington, Seattle WA USA; Dator, Romel [Department of Pathology, University of Washington, Seattle WA USA; Wu, Rui [Department of Pathology, University of Washington, Seattle WA USA; Department of Pathology, No. 3 Hospital of Beijing University, Beijing China; Aro, Patrick [Department of Pathology, University of Washington, Seattle WA USA; Schuster, Robert J. [Department of Pathology, University of Washington, Seattle WA USA; Ginghina, Carmen [Department of Pathology, University of Washington, Seattle WA USA; Pan, Catherine [Department of Pathology, University of Washington, Seattle WA USA; Gao, Yuqian [Pacific Northwest National Laboratory, Richland WA USA; Qian, Weijun [Pacific Northwest National Laboratory, Richland WA USA; Zabetian, Cyrus P. [Parkinson' s Disease Research and Geriatric Research, Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle WA USA; Department of Neurology, University of Washington School of Medicine, Seattle WA USA; Hu, Shu-Ching [Department of Neurology, University of Washington School of Medicine, Seattle WA USA; Quinn, Joseph F. [Department of Neurology, Oregon Health and Science University, Portland OR USA; Zhang, Jing [Department of Pathology, University of Washington, Seattle WA USA; Department of Pathology, Peking University Health Science Centre and Third Hospital, Beijing 100083 China

    2017-04-19

    Aim: The alpha-synuclein (α-syn) level in human cerebrospinal fluid (CSF), as measured by immunoassays, is promising as a Parkinson’s disease (PD) biomarker. However, the levels of total α-syn are inconsistent among studies with large cohorts and different measurement platforms. Total α-syn level also does not correlate with disease severity or progression. Here, we developed a highly sensitive Multiple Reaction Monitoring (MRM) method to measure absolute CSF α-syn peptide concentrations without prior enrichment or fractionation, aiming to discover new candidate biomarkers. Results: Six peptides covering 73% of protein sequence were reliably identified, and two were consistently quantified in cross-sectional and longitudinal cohorts. Absolute concentration of α-syn in human CSF was determined to be 2.1ng/mL. A unique α-syn peptide, TVEGAGSIAAATGFVK (81-96), displayed excellent correlation with previous immunoassay results in two independent PD cohorts (p < 0.001), correlated with disease severity, and its changes significantly tracked the disease progression longitudinally. Conclusions: An MRM assay to quantify human CSF α-syn was developed and optimized. Sixty clinical samples from cross-sectional and longitudinal PD cohorts were analyzed with this approach. Although further larger-scale validation is needed, the results suggest that α-syn peptide could serve as a promising biomarker in PD diagnosis and progression.

  1. Monitoring of tumor growth and metastasis potential in MDA-MB-435s/ tk-luc human breast cancer xenografts

    Science.gov (United States)

    Chang, Ya-Fang; Lin, Yi-Yu; Wang, Hsin-Ell; Liu, Ren-Shen; Pang, Fei; Hwang, Jeng-Jong

    2007-02-01

    Molecular imaging of reporter gene expression provides a rapid, sensitive and non-invasive monitoring of tumor behaviors. In this study, we reported the establishment of a novel animal model for longitudinal examination of tumor growth kinetics and metastatic spreading in vivo. The highly metastatic human breast carcinoma MDA-MB-435s cell line was engineered to stably express herpes simplex virus type 1 thymidine kinase (HSV-1- tk) and luciferase ( luc). Both 131I-FIAU and D-luciferin were used as reporter probes. For orthotopic tumor formation, MDA-MB-435s/ tk-luc cells were implanted into the first nipple of 6-week-old female NOD/SCID mice. For metastatic study, cells were injected via the lateral tail vein. Mice-bearing MDA-MB-435s/ tk-luc tumors were scanned for tumor growth and metastatsis using Xenogen IVIS50 system. Gamma scintigraphy and whole-body autoradiography were also applied to confirm the tumor localization. The results of bioluminescence imaging as well as histopathological finding showed that tumors could be detected in femur, spine, ovary, lungs, kidney, adrenal gland, lymph nodes and muscle at 16 weeks post i.v. injection, and correlated photons could be quantified. This MDA-MB-435s/ tk-luc human breast carcinoma-bearing mouse model combined with multimodalities of molecular imaging may facilitate studies on the molecular mechanisms of cancer invasion and metastasis.

  2. Modeling atmospheric transport of CO2 at High Resolution to estimate the potentialities of spaceborne observation to monitor anthropogenic emissions

    Science.gov (United States)

    Ciais, P.; Chimot, J.; Klonecki, A.; Prunet, P.; Vinuessa, J.; Nussli, C.; Breon, F.

    2010-12-01

    There is a crucial and urgent need to quantify and monitor anthropogenic fossil fuel emissions of CO2. Spaceborne measurements, such as those from GOSAT or the forthcoming OCO-2, or other space missions in preparation, could provide the necessary information, in particular over regions with few in-situ measurements of atmospheric concentration are too scarce. Contrarily to biogenic flux, anthropogenic emissions are highly heterogeneous in space with typical values that vary by several orders of magnitudes. A proper analysis of the impact of anthropogenic emissions on the atmospheric concentration of CO2 therefore requires a high spatial resolution, typically of a few km. Simulations of the transport of fossil CO2 plumes were performed with a resolution of 1 km over the main industrialized regions of France, and using other models of lower resolution to account for the influence of distant sources advected into the area of interest. The results clearly show the plumes from intense yet localized sources, such as urban areas or power plants, and how their structures vary with the meteorology (wind speed and direction). They also show that the plume from distant sources, such as the large emission from Northern Europe, may sometime mask the local plume, even from large cities like Paris or Lyon. These atmospheric transport simulations are then sampled according to cloud cover, spaceborne instrument sampling and typical errors, to analyze the information content of the remote sensing data and how they can improve the current knowledge on anthropogenic emissions.

  3. Genetic identity of brook trout in Lake Superior south shore streams: Potential for genetic monitoring of stocking and rehabilitation efforts

    Science.gov (United States)

    Sloss, Brian L.; Jennings, Martin J.; Franckowiak, R.; Pratt, D.M.

    2008-01-01

    Rehabilitation of migratory ('coaster') brook trout Salvelinus fontinalis along Lake Superior's south shore is a topic of high interest among resource stakeholders and management agencies. Proposed strategies for rehabilitation of this brook trout life history variant in Wisconsin include supplemental stocking, watershed management, habitat rehabilitation, harvest regulations, or a combination thereof. In an effort to evaluate the success of coaster brook trout rehabilitation efforts, we collected genetic data from four populations of interest (Whittlesey Creek, Bois Brule River, Bark River, and Graveyard Creek) and the hatchery sources used in the Whittlesey Creek supplementation experiment. We characterized the genetic diversity of 30 individuals from each of four populations using 13 microsatellite DNA loci. Levels of genetic variation were consistent with those in similar studies conducted throughout the basin. Significant genetic variation among the populations was observed, enabling adequate population delineation through assignment tests. Overall, 208 of the 211 sampled fish (98.6%) were correctly assigned to their population of origin. Simulated F1 hybrids between two hatchery strains and the Whittlesey Creek population were identifiable in the majority of attempts (90.5-100% accuracy with 0-2.5% error). The genetic markers and analytical techniques described provide the ability to monitor the concurrent coaster brook trout rehabilitation efforts along Wisconsin's Lake Superior south shore, including the detection of hybridization between hatchery and native populations. ?? Copyright by the American Fisheries Society 2008.

  4. Monitoring of tumor growth and metastasis potential in MDA-MB-435s/tk-luc human breast cancer xenografts

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Y.-F. [Department of Radiological Sciences, National Yang-Ming University, 155, Sec. 2, Li-Nong Street, Pei-tou 112, Taipei, Taiwan (China); Lin, Y.-Y. [Department of Radiological Sciences, National Yang-Ming University, 155, Sec. 2, Li-Nong Street, Pei-tou 112, Taipei, Taiwan (China); Wang, H.-E. [Department of Radiological Sciences, National Yang-Ming University, 155, Sec. 2, Li-Nong Street, Pei-tou 112, Taipei, Taiwan (China); Liu, R.-S. [Department of Nuclear Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan (China); Nuclear Medicine Department, Veterans General Hospital, Taipei, Taiwan (China); Pang Fei [Department of Veterinary Medicine, National Taiwan University, Taipei, Taiwan (China); Hwang, J.-J. [Department of Radiological Sciences, National Yang-Ming University, 155, Sec. 2, Li-Nong Street, Pei-tou 112, Taipei, Taiwan (China)]. E-mail: jjhwang@ym.edu.tw

    2007-02-01

    Molecular imaging of reporter gene expression provides a rapid, sensitive and non-invasive monitoring of tumor behaviors. In this study, we reported the establishment of a novel animal model for longitudinal examination of tumor growth kinetics and metastatic spreading in vivo. The highly metastatic human breast carcinoma MDA-MB-435s cell line was engineered to stably express herpes simplex virus type 1 thymidine kinase (HSV-1-tk) and luciferase (luc). Both {sup 131}I-FIAU and D-luciferin were used as reporter probes. For orthotopic tumor formation, MDA-MB-435s/tk-luc cells were implanted into the first nipple of 6-week-old female NOD/SCID mice. For metastatic study, cells were injected via the lateral tail vein. Mice-bearing MDA-MB-435s/tk-luc tumors were scanned for tumor growth and metastatsis using Xenogen IVIS50 system. Gamma scintigraphy and whole-body autoradiography were also applied to confirm the tumor localization. The results of bioluminescence imaging as well as histopathological finding showed that tumors could be detected in femur, spine, ovary, lungs, kidney, adrenal gland, lymph nodes and muscle at 16 weeks post i.v. injection, and correlated photons could be quantified. This MDA-MB-435s/tk-luc human breast carcinoma-bearing mouse model combined with multimodalities of molecular imaging may facilitate studies on the molecular mechanisms of cancer invasion and metastasis.

  5. Interface potential sensing from adsorption of human serum albumin (HSA) on carbon nanotube (CNT) monitored by zero current potentiometry for HSA determination.

    Science.gov (United States)

    Wang, Huan; Wu, Yi; Song, Jun-Feng

    2015-10-15

    In this work, the adsorption of human serum albumin (HSA) on the bare multiwall carbon nanotube (MWNT) was investigated by a new electrochemical method, termed as zero current potentiometry. For this, a MWNT strip was prepared by directly adhering MWNTs on the transparent adhesive tape surface. Moreover, when HSA adsorbed onto MWNT at the MWNT/solution interface, an interface potential Ψ yielded. The interface potential Ψ as the zero current potential Ezcp simply related to it was monitored by zero current potentiometry. The relationship between the zero current potential Ezcp, the HSA concentration and others was established in simple stoichiometric relation. Based on this, both the adsorption of HSA on MWNT and the HSA determination can be studied. For the HSA determination, the theoretic conclusion consisted with experimental results. The zero current potential Ezcp was proportional to the HSA concentration in the range of 2.8 × 10(-8) - 3.4 × 10(-7)M with the limit of detection 2 × 10(-8)M. The linear regression equation was Ezcp/V (vs, SCE) = (0.159 ± 0.01) + (0.358 ± 0.02) × 10(6)CHSA (µM). This determination was fast, high sensitive and good selective.

  6. Surveillance of Aedes aegypti (L.) Mosquitoes in Mumbai International Seaport (India) to Monitor Potential Global Health Risks

    OpenAIRE

    Kaushal Kumar; Abhay Kumar Sharma; Manas Sarkar; Arun Chauhan; Rajeev Sharma

    2014-01-01

    Aedes mosquitoes are highly invasive and can survive almost any climatic conditions. They transmit a number of major world's deadly diseases. Therefore, a study was undertaken during December 2010 to evaluate the entomo-epidemiological risk of Aedes mosquito borne diseases (VBD) in Mumbai international seaport areas to minimize potential global health risks and prevent introduction of new VBD in India. Surveys were undertaken in operational and residential areas of Mumbai Port Trust (MPT). Al...

  7. Biofield potential simulation as a novel adjunt modality for continuous monitoring of breast lesions: a 3D numerical model.

    Science.gov (United States)

    Ng, E Y K; Ng, W K; Acharya, U Rajendra

    2008-01-01

    Breast cancer is a disease characterized by the uncontrolled growth of abnormal cells. Early detection of this disease is the most effective way to reduce mortality. Although several new technologies show promise for improved capability of diagnosis, none have yet proved superior to traditional, X-ray film mammography in screening for breast cancer. More evaluation and development of new imaging tools and of promising skin surface electrical potential techniques is required and warranted. In the present study, we propose a theoretical three-dimensional, simplified and realistic model of the female breast to distinguish the surface biopotential in different types of breast abnormalities. We developed an inhomogeneous female breast model, closer to the actual, by considering the breast as a hemisphere with various layers of unequal thickness in supine condition. In order to determine the potential distribution developed, isotropic homogeneous conductivity was assigned to each of these compartments and the volume conductor problem was solved using finite element method. Richardson extrapolation for grid invariance test was used to ensure the results are of reliable accuracy. The simulation results show that the surface potentials are sensitive to the presence of tumour, location and placement of the electrodes.

  8. Relationship between Multi-Output Partially Bent Functions and Multi-Output Bent Functions

    Institute of Scientific and Technical Information of China (English)

    ZHAO Yaqun; JU Guizhi; WANG Jue

    2006-01-01

    In this paper, the definition of multi-output partially Bent functions is presented and some properties are discussed. Then the relationship between multi-output partially Bent functions and multi-output Bent functions is given in Theorem 4, which includes Walsh spectrum expression and function expression. This shows that multi-output partially Bent functions and multi-output Bent functions can define each other in principle. So we obtain the general method to construct multi-output partially Bent functions from multi-output Bent functions.

  9. Analysis of output trends from Varian 2100C/D and 600C/D accelerators.

    Science.gov (United States)

    Grattan, M W D; Hounsell, A R

    2011-01-07

    Analysis of Varian linear accelerator output trends is reported. Two groups, consisting of four matched Varian 2100C/D and four matched Varian 600C/D accelerators, with different designs of monitor chamber, have been investigated and the data acquired from regular calibrated ion chamber/electrometer measurements of the output performance of the eight accelerators analysed. The trend of machine output with time, having removed the effect of adjusting the monitor chamber response, was compared on a monthly and annual basis for monitor chambers with ages ranging between 1 year and 7 years. The results indicate that the response is generally consistent within each set of accelerators with different monitor chamber designs. Those used in a Varian 600C/D machine result in a reduction in measured output over time, with an average monthly reduction of 0.35 ± 0.09% over the course of the first 4 years of use. The chambers used in a 2100C/D accelerator result in an increase in measured output over time, with an average monthly increase of 0.26 ± 0.09% over the course of the first 4 years of use. The output increase then reduces towards the end of this period of time, with the average monthly change falling to -0.03 ± 0.02% for the following 3 years. The output response trend was similar for all clinical energies used on the 2100C/D accelerators--6, 15 MV x-ray beams, and 4, 6, 9, 12, 16 and 20 MeV electron beams. By tracking these changes it has been possible to predict the response over time to allow appropriate adjustments in monitor chamber response to maintain a measured accelerator output within tolerance and give confidence in performance. It has also provided data to indicate the need for planned preventative intervention and indicate if the monitor chamber response is behaving as expected.

  10. Alternative techniques to monitoring the corrosive potential for fluids in submarine pipelines; Tecnicas alternativas para monitorar o potencial corrosivo de fluidos transportados em oleodutos submarinos

    Energy Technology Data Exchange (ETDEWEB)

    Andrade, Cynthia de Azevedo; Brito, Rosane Fernandes de; Paiva, Eva M. de O. [PETROBRAS, Rio de Janeiro, RJ (Brazil). Centro de Pesquisas (CENPES). Tecnologia de Materiais, Equipamentos e Corrosao; Freitas, Nair Domingues de; Salvador, Angelica Dias [PETROBRAS, Macae, RJ (Brazil). Unidade de Negocios da Bacia de Campos

    2003-07-01

    PETROBRAS in search of being a benchmark in safety, environment and health, established in July 2001 a work group to elaborate a standard for Pipeline Integrity Management. This standard set the requirements for Pipeline Integrity Management and establishes, among others criteria, the actions required to detect, monitor and control internal corrosion of pipelines. The first step to evaluate, monitor and control the internal corrosion is to define the corrosive potential of transported fluids. Some oil pipelines located in central and southern areas of the Campos Basin transport high water cut produced fluids (> 30%) and with demulsifiers, which allow oil and water separation and increase internal corrosion risks. Despite of these, it is not possible to check the internal corrosion rates using conventional techniques because the fluids are produced through sub-sea 'manifolds'. In order to investigate the possibility of corrosion inhibition by crude oils, laboratory tests were performed simulating real field conditions in terms of fluid compositions, water cut and temperature. Experiments were conducted to determine the corrosion rate of specimens, the emulsion stability and the initial temperature of wax precipitation. This paper presents the results of the study realized to define the fluids' corrosive potential of four Campos Basin platforms that are transported through sub-sea 'manifolds. (author)

  11. Potential of multisyringe chromatography for the on-line monitoring of the photocatalytic degradation of antituberculosis drugs in aqueous solution.

    Science.gov (United States)

    Guevara-Almaraz, E; Hinojosa-Reyes, L; Caballero-Quintero, A; Ruiz-Ruiz, E; Hernández-Ramírez, A; Guzmán-Mar, J L

    2015-02-01

    In this study, a multisyringe chromatography system (MSC) using a C18 monolithic column was proposed for the on-line monitoring of the photocatalytic degradation of isoniazid (INH, 10 mg L(-1)) and pyrazinamide (PYRA, 5mgL(-1)) mixtures in aqueous solution using a small sample volume (200 μL) with an on-line filtration device in a fully automated approach. During the photocatalytic oxidation using TiO2 or ZnO semiconductor materials, total organic carbon (TOC) and the formed intermediates were analyzed off-line using ion chromatography, ion exclusion HPLC, and ESI-MS/MS. The results showed that TiO2 exhibits a better photocatalytic activity than ZnO under UV irradiation (365 nm) for the degradation of INH and PYRA mixtures, generating 97% and 92% degradation, respectively. The optimal oxidation conditions were identified as pH 7 and 1.0 g L(-1) of TiO2 as catalyst. The mineralization of the initial organic compounds was confirmed by the regular decrease in TOC, which indicated 63% mineralization, and the quantitative release of nitrate and nitrite ions, which represent 33% of the nitrogen in these compounds. The major intermediates of INH degradation included isonicotinamide, isonicotinic acid, and pyridine, while the ESI-MS/MS analysis of PYRA aqueous solution after photocatalytic treatment showed the formation of pyrazin-2-ylmethanol, pyrazin-2-ol, and pyrazine. Three low-molecular weight compounds, acetamide, acetic acid and formic acid, were detected during INH and PYRA decomposition. PYRA was more resistant to photocatalytic degradation due to the presence of the pyrazine ring, which provides greater stability against OH attack.

  12. Mitigation potential of horizontal ground coupled heat pumps for current and future climatic conditions: UK environmental modelling and monitoring studies

    Science.gov (United States)

    García González, Raquel; Verhoef, Anne; Vidale, Pier Luigi; Gan, Guohui; Wu, Yupeng; Hughes, Andrew; Mansour, Majdi; Blyth, Eleanor; Finch, Jon; Main, Bruce

    2010-05-01

    An increased uptake of alternative low or non-CO2 emitting energy sources is one of the key priorities for policy makers to mitigate the effects of environmental change. Relatively little work has been undertaken on the mitigation potential of Ground Coupled Heat Pumps (GCHPs) despite the fact that a GCHP could significantly reduce CO2 emissions from heating systems. It is predicted that under climate change the most probable scenario is for UK temperatures to increase and for winter rainfall to become more abundant; the latter is likely to cause a general rise in groundwater levels. Summer rainfall may reduce considerably, while vegetation type and density may change. Furthermore, recent studies underline the likelihood of an increase in the number of heat waves. Under such a scenario, GCHPs will increasingly be used for cooling as well as heating. These factors will affect long-term performance of horizontal GCHP systems and hence their economic viability and mitigation potential during their life span ( 50 years). The seasonal temperature differences encountered in soil are harnessed by GCHPs to provide heating in the winter and cooling in the summer. The performance of a GCHP system will depend on technical factors (heat exchanger (HE) type, length, depth, and spacing of pipes), but also it will be determined to a large extent by interactions between the below-ground parts of the system and the environment (atmospheric conditions, vegetation and soil characteristics). Depending on the balance between extraction and rejection of heat from and to the ground, the soil temperature in the neighbourhood of the HE may fall or rise. The GROMIT project (GROund coupled heat pumps MITigation potential), funded by the Natural Environment Research Council (UK), is a multi-disciplinary research project, in collaboration with EarthEnergy Ltd., which aims to quantify the CO2 mitigation potential of horizontal GCHPs. It considers changing environmental conditions and combines

  13. Aerosol Emission Monitoring and Assessment of Potential Exposure to Multi-walled Carbon Nanotubes in the Manufacture of Polymer Nanocomposites.

    Science.gov (United States)

    Thompson, Drew; Chen, Sheng-Chieh; Wang, Jing; Pui, David Y H

    2015-11-01

    Recent animal studies have shown that carbon nanotubes (CNTs) may pose a significant health risk to those exposed in the workplace. To further understand this potential risk, effort must be taken to measure the occupational exposure to CNTs. Results from an assessment of potential exposure to multi-walled carbon nanotubes (MWCNTs) conducted at an industrial facility where polymer nanocomposites were manufactured by an extrusion process are presented. Exposure to MWCNTs was quantified by the thermal-optical analysis for elemental carbon (EC) of respirable dust collected by personal sampling. All personal respirable samples collected (n = 8) had estimated 8-h time weighted average (TWA) EC concentrations below the limit of detection for the analysis which was about one-half of the recommended exposure limit for CNTs, 1 µg EC/m(3) as an 8-h TWA respirable mass concentration. Potential exposure sources were identified and characterized by direct-reading instruments and area sampling. Area samples analyzed for EC yielded quantifiable mass concentrations inside an enclosure where unbound MWCNTs were handled and near a pelletizer where nanocomposite was cut, while those analyzed by electron microscopy detected the presence of MWCNTs at six locations throughout the facility. Through size selective area sampling it was identified that the airborne MWCNTs present in the workplace were in the form of large agglomerates. This was confirmed by electron microscopy where most of the MWCNT structures observed were in the form of micrometer-sized ropey agglomerates. However, a small fraction of single, free MWCNTs was also observed. It was found that the high number concentrations of nanoparticles, ~200000 particles/cm(3), present in the manufacturing facility were likely attributable to polymer fumes produced in the extrusion process. © The Author 2015. Published by Oxford University Press on behalf of the British Occupational Hygiene Society.

  14. Effects of curcumin on cancer cell mitochondrial function and potential monitoring with ¹⁸F-FDG uptake.

    Science.gov (United States)

    Jung, Kyung-Ho; Lee, Jin Hee; Park, Jin Won; Moon, Seung-Hwan; Cho, Young Seok; Choe, Yearn Seong; Lee, Kyung-Han

    2016-02-01

    A better understanding of how curcumin influences cancer cell biology could help devise new strategies to enhance its antitumor effect. Many curcumin actions are proposed to occur by targeting mitochondrial function, among which glucose metabolism and reactive oxygen species (ROS) production are pivotal. However, little is known of how curcumin influences cancer cell glucose metabolism. We thus evaluated the effect of curcumin on cancer cell glucose metabolism and mitochondrial function, and further investigated whether these responses could be modified to enhance the anticancer potency of the compound. MCF-7 breast cancer cells treated with curcumin were measured for 18F-fluorodeoxyglucose (18F‑FDG) uptake, lactate production, hexokinase activity, oxygen consumption rate (OCR), ROS production and mitochondrial membrane potential (MMP). Activation of signaling pathways was evaluated by western blots, and cell survival was assessed with sulforhodamine B assays. Curcumin stimulated a 3.6-fold increase of 18F-FDG uptake in MCF-7 cells, along with augmented hexokinase activity and lactate efflux. This was accompanied by significantly suppressed cellular OCR, consistent with a metabolic shift to glycolytic flux. Inhibiting this metabolic response with 2-deoxyglucose (2-DG) blocked curcumin-induced mTOR activation and resulted in a greater anti-proliferative effect. Curcumin-induced MMP depolarization led to reduced ROS production, which may hinder the anticancer effect of the compound. Intracellular ROS was completely restored by adding Cu2+, which can bind and modify the curcumin's physico-chemical property, and this resulted in a marked potentiation of its anti-proliferative effect. Thus, curcumin suppresses cancer cell MMP and ROS generation, and this response is accompanied by stimulated 18F-FDG uptake via shifting of metabolism from mitochondrial respiration to glycolytic flux. These mitochondrial and metabolic responses may provide potential targets that can

  15. 脉波指示剂连续心排血量监测技术在早期目标导向治疗中的临床作用分析%Pulse Indicator Continuous Cardiac Output for Hemodynamics Monitoring in Patients with Septic Shock

    Institute of Scientific and Technical Information of China (English)

    陈刚; 王标; 郭小芙

    2014-01-01

    Objective To investigate the application of pulse index continuous cardiac output (PiCCO) in patients with septic shock.MethodsSixty patients with septic shock were randomly divided into two groups: routine monitoring group and PiCCO monitoring group, with 30 patients in each group. The rate of reaching standard of early goal directed therapy (EGDT) was observed after treatment for 6, 24 and 48 hours. In addition, blood lactic acid, central venous oxygen saturation (ScvO2), central venous pressure (CVP), mean arterial pressure (MAP) and urine volume were determined after treatment for 6, 24 and 48 hours, and positive fluid balance amount and dosages of dopamine and dobutamine were measured after treatment for 6, 24 and 48 hours. Mortality was observed in the patients of both groups.Results After treatment for 6, 24 and 48 hours, in PiCCO monitoring group, ScvO2 signifi cantly increased, blood lactic acid level, positivefl uid balance amount, dosages of dopamine and dobutamine signifi cantly decreased compared with routine monitoring group (P<0.05). The rate of reaching standard of EGDT in PiCCO monitoring group was signifi cantly higher than that in routine monitoring group after treatment for 6, 24 hours. There also was difference in mortality between the two groups (P<0.05).Conclusion PiCCO monitor has an important clinical guide signifi cance for the resuscitation of septic shock, which can help to reach the fast and effective treatment target, improve septic shock, avoid the damage of blindfl uid infusion, provide fast and right treatment evidence. So it is worth being spread in clinic treatment.%目的:探讨脉波指示剂连续心排血量监测(PiCCO)技术在脓毒性休克患者早期目标导向治疗(EGDT)中的临床指导价值。方法将60例脓毒性休克患者按随机数字表法分为常规监测组和PiCCO监测组各30例,PiCCO监测组在PiCCO技术指导下行EGDT,常规监测组患者放置中心静脉导管和桡动脉导

  16. Pulse Indicator Continuous Cardiac Output for Hemodynamics Monitoring in Patients with Septic Shock%脉搏指示连续心排血量监测(PiCCO)在脓毒症休克患者血流动力学监测中的临床价值

    Institute of Scientific and Technical Information of China (English)

    伊敏; 么改琦; 朱曦; 郭向阳

    2013-01-01

    目的 探讨脉搏指示连续心排血量监测技术(pulse indicator continuous cardiac output,PiCCO)在脓毒症休克患者血流动力学监测中的临床价值. 方法 2012年1~8月,前瞻性队列研究比较常规监测(n=12)与PiCCO监测(n=19)脓毒症休克患者的血流动力学,应用PiCCO监测指导脓毒症休克患者的液体复苏、血管收缩药和正性肌力药物的使用. 结果 2组脓毒症休克患者性别、年龄、原发病、既往病史、多器官功能不全综合征(MODS)的发生和发生MODS器官数、急性生理学及慢性健康状况评分系统(APACHE)Ⅱ、脓毒症相关器官衰竭评分(SOFA)、应用去甲肾上腺素剂量和入ICU后7天总的输液量差异均无显著性,PiCCO组初始平均动脉压(MAP)明显低于常规组[(52.00±5.00)mm Hg vs.(59.58±3.42)mm Hg,t=4.603,P=0.000],而对于PiCCO组存在心功能损害的患者应用正性肌力药治疗后达到与常规组相同的MAP达标值[(68.00±2.43)mm Hg vs.(68.58±2.88)mm Hg,t=0.607,P=0.549],2组MAP达标值差异无显著性. 结论 在PiCCO监测指导下,可以对于存在心功能损害的患者应用正性肌力药物,而不是仅应用血管收缩药升高血压.%Objective To investigate the clinical value of pulse indicator continuous cardiac output ( PiCCO) in hemodynamics monitoring for patients with septic shock. Methods A prospective cohort study comparing routine hemodynamics monitoring (n = 12) and PiCCO (n = 19) for patients with septic shock were carried out from January to August 2012. The PiCCO monitor provided a continuous assessment of fluid resuscitation, vasopressors and inotropes infusion in septic shock patients. Results There were no significant difference between the two groups in sex, age, etiology of critical illness, medical history, incidence of MODS, number of MODS involved organ, APACHE Ⅱ and SOFA scores, usage of noradrenaline, and total volume of fluid infusion in a week. In the PiCCO group, the original MAP

  17. Signal processing for solar array monitoring, fault detection, and optimization

    CERN Document Server

    Braun, Henry; Spanias, Andreas

    2012-01-01

    Although the solar energy industry has experienced rapid growth recently, high-level management of photovoltaic (PV) arrays has remained an open problem. As sensing and monitoring technology continues to improve, there is an opportunity to deploy sensors in PV arrays in order to improve their management. In this book, we examine the potential role of sensing and monitoring technology in a PV context, focusing on the areas of fault detection, topology optimization, and performance evaluation/data visualization. First, several types of commonly occurring PV array faults are considered and detection algorithms are described. Next, the potential for dynamic optimization of an array's topology is discussed, with a focus on mitigation of fault conditions and optimization of power output under non-fault conditions. Finally, monitoring system design considerations such as type and accuracy of measurements, sampling rate, and communication protocols are considered. It is our hope that the benefits of monitoring presen...

  18. Output order in immediate serial recall.

    Science.gov (United States)

    Tan, Lydia; Ward, Geoff

    2007-07-01

    In two experiments, we examined the effect of output order in immediate serial recall (ISR). In Experiment 1, three groups of participants saw lists of eight words and wrote down the words in the rows corresponding to their serial positions in an eight-row response grid. One group was precued to respond in forward order, a second group was precued to respond in any order, and a third group was postcued for response order. There were significant effects of output order, but not of cue type. Relative to the forward output order, the free output order led to enhanced recency and diminished primacy, with superior performance for words output early in recall. These results were replicated in Experiment 2 using six-item lists, which further suggests that output order plays an important role in the primacy effect in ISR and that the recency items are most highly accessible at recall.

  19. Experimental model of enterotoxigenic Escherichia coli infection in pigs: potential for an early recognition of colibacillosis by monitoring of behavior.

    Science.gov (United States)

    Krsnik, B; Yammine, R; Pavicić, Z; Balenović, T; Njari, B; Vrbanac, I; Valpotić, I

    1999-10-01

    The hypothesis that altered behavior is a sign for an early recognition of disease was tested. The experiment was conducted to evaluate the behavioral patterns of pigs in a model of postweaning colibacillosis. Twenty-five weaned pigs (from a herd that was previously found to be highly susceptible to F4+ Escherichia coli strains) were randomly assigned into 5 groups, kept in isolated pens under the controlled ambiental conditions. One day after weaning, the pigs from three groups were intragastrically inoculated (via orogastric tube) with either F4ac+ (1466 or 2407) or F4- (1467) nonenterotoxigenic E. coli (non-ETEC) strains, respectively. The pigs from the fourth group were inoculated with F4ac+ ETEC strain M1823 and the remaining 5 pigs that received broth containing 1.2% sodium bicarbonate were kept as noninoculated controls. The pigs were examined daily and the frequency and duration of their behavioral patterns, such as eating, drinking, lying, standing, urinating, defecating, rooting and playing were monitored for 300 h during a period of 10 days. In this model, three conditions were also observed in F4-susceptible pigs: (1) acute fatal diarrheal disease; (2) moderate diarrhea and weight loss and (3) no diarrhea and weight loss. The incidence (both frequency and duration) of defecating was significantly higher (P < 0.05) in pigs inoculated with F4ac+ ETEC strain M1823 as compared to that of noninoculated (control) pigs. Pigs inoculated with F4ac+ non-ETEC strain 1466 had a significantly lower frequency of eating (P < 0.05) and frequency/duration of drinking (P < 0.05) than did the controls. The 1466-inoculated pigs, had an increased diarrhea score, but frequency/duration of defecating was not significantly different. Pigs inoculated with F4ac+ non-ETEC strain 2407 spent more time in lying (P < 0.05) than did noninoculated pigs. Conversely, the pigs that received F4- non-ETEC strain 1467 laid shorter (P < 0.05) and ate/drank less frequently (P < 0.05) than the

  20. Output Regulation of the Arneodo Chaotic System

    OpenAIRE

    Sundarapandian Vaidyanathan

    2010-01-01

    This paper solves the problem of regulating the output of the Arneodo chaotic system (1981), which is one of the paradigms of chaotic dynamical systems. Explicitly, using the state feedback control laws, the output of the Arneodo chaotic system is regulated so as to track constant reference signals as well as to track periodic reference signals. The control laws are derived using the regulator equations of Byrnes and Isidori (1990), which provide the solution of the output regulation problem ...

  1. Probabilistic Output Analysis by Program Manipulation

    OpenAIRE

    Rosendahl, Mads; Kirkeby, Maja H.

    2015-01-01

    The aim of a probabilistic output analysis is to derive a probability distribution of possible output values for a program from a probability distribution of its input. We present a method for performing static output analysis, based on program transformation techniques. It generates a probability function as a possibly uncomputable expression in an intermediate language. This program is then analyzed, transformed, and approximated. The result is a closed form expression that computes an over...

  2. The Global NR Output Kept Rising

    Institute of Scientific and Technical Information of China (English)

    Bo Wen

    2011-01-01

    In early November, Association of Natural Rubber Producing Countries in- dicated that from 2005 to 2011, the pro- ducing area and output of the global NR both kept rising. As predicted, the pro- ducing area will be 72 million hectares, the output will be 10.02 million tons and the average output will be 1,392 kg/hectare by the end of2011.

  3. Sinopec H1 Oil Output Climbs Slightly

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    Sinopec Corp., China's largest oil refiner, announced in late-July that its crude oil output rose 4.33 percent to 163 million barrels year-on-year in the first half. Domestic crude oil output was up 1. 16 percent to 152 million barrels during the period, while overseas output jtmlped 82.46 percent to 11,13 million barrels, according to an unaudited repo,t released by tile company.

  4. A compact nanopower low output impedance CMOS operational amplifier for wireless intraocular pressure recordings.

    Science.gov (United States)

    Dresher, Russell P; Irazoqui, Pedro P

    2007-01-01

    Wireless sensing has shown potential benefits for the continuous-time measurement of physiological data. One such application is the recording of intraocular pressure (IOP) for patients with glaucoma. Ultra-low-power circuits facilitate the use of inductively-coupled power for implantable wireless systems. Compact circuit size is also desirable for implantable systems. As a first step towards the realization of such circuits, we have designed a compact, ultra-low-power operational amplifier which can be used to record IOP. This paper presents the measured results of a CMOS operational amplifier that can be incorporated with a wireless IOP monitoring system or other low-power application. It has a power consumption of 736 nW, chip area of 0.023 mm2, and output impedance of 69 Omega to drive low-impedance loads.

  5. On-line analysis of middle latency auditory evoked potentials (MLAEP) for monitoring depth of anaesthesia in laboratory rats

    DEFF Research Database (Denmark)

    Jensen, E W; Nygaard, M; Henneberg, S W

    1998-01-01

    using neuromuscular blocking agents (NMBA). A number of studies suggest that the Middle Latency Auditory Evoked Potentials (MLAEP) contain information about the state of consciousness in humans. The purpose of this study was to examine whether the AEP could serve as an indicator of depth of anaesthesia...... and decreasing gradually to a level between 50 and 20 as the rat was anaesthetised. Nine rats were anaesthetised and included in the study. Four doses of Hypnorm vet. and Dormicum were given as a total, each with 5 minutes interval. Clinical signs of the level of anaesthesia were observed simultaneously...... with the AEP. The results showed that in four rats DAI decreased to a level below 30 while anaesthetised. In the remaining five rats the AEP was only decreased to a level below 45. The results indicated that a simple dosing regimen based on weight was unable to give the same depth of anaesthesia in individual...

  6. Basal ganglia outputs map instantaneous position coordinates during behavior.

    Science.gov (United States)

    Barter, Joseph W; Li, Suellen; Sukharnikova, Tatyana; Rossi, Mark A; Bartholomew, Ryan A; Yin, Henry H

    2015-02-11

    The basal ganglia (BG) are implicated in many movement disorders, yet how they contribute to movement remains unclear. Using wireless in vivo recording, we measured BG output from the substantia nigra pars reticulata (SNr) in mice while monitoring their movements with video tracking. The firing rate of most nigral neurons reflected Cartesian coordinates (either x- or y-coordinates) of the animal's head position during movement. The firing rates of SNr neurons are either positively or negatively correlated with the coordinates. Using an egocentric reference frame, four types of neurons can be classified: each type increases firing during movement in a particular direction (left, right, up, down), and decreases firing during movement in the opposite direction. Given the high correlation between the firing rate and the x and y components of the position vector, the movement trajectory can be reconstructed from neural activity. Our results therefore demonstrate a quantitative and continuous relationship between BG output and behavior. Thus, a steady BG output signal from the SNr (i.e., constant firing rate) is associated with the lack of overt movement, when a stable posture is maintained by structures downstream of the BG. Any change in SNr firing rate is associated with a change in position (i.e., movement). We hypothesize that the SNr output quantitatively determines the direction, velocity, and amplitude of voluntary movements. By changing the reference signals to downstream position control systems, the BG can produce transitions in body configurations and initiate actions.

  7. Dynamic dual-energy chest radiography: a potential tool for lung tissue motion monitoring and kinetic study.

    Science.gov (United States)

    Xu, Tong; Ducote, Justin L; Wong, Jerry T; Molloi, Sabee

    2011-02-21

    Dual-energy chest radiography has the potential to provide better diagnosis of lung disease by removing the bone signal from the image. Dynamic dual-energy radiography is now possible with the introduction of digital flat-panel detectors. The purpose of this study is to evaluate the feasibility of using dynamic dual-energy chest radiography for functional lung imaging and tumor motion assessment. The dual-energy system used in this study can acquire up to 15 frames of dual-energy images per second. A swine animal model was mechanically ventilated and imaged using the dual-energy system. Sequences of soft-tissue images were obtained using dual-energy subtraction. Time subtracted soft-tissue images were shown to be able to provide information on regional ventilation. Motion tracking of a lung anatomic feature (a branch of pulmonary artery) was performed based on an image cross-correlation algorithm. The tracking precision was found to be better than 1 mm. An adaptive correlation model was established between the above tracked motion and an external surrogate signal (temperature within the tracheal tube). This model is used to predict lung feature motion using the continuous surrogate signal and low frame rate dual-energy images (0.1-3.0 frames per second). The average RMS error of the prediction was (1.1 ± 0.3) mm. The dynamic dual energy was shown to be potentially useful for lung functional imaging such as regional ventilation and kinetic studies. It can also be used for lung tumor motion assessment and prediction during radiation therapy.

  8. Application of pulse indicator continuous cardiac output monitor in the fluid resuscitation therapy in elderly patients with septic shock%脉搏指示连续心排血量监护仪在老年感染性休克液体复苏治疗中的应用

    Institute of Scientific and Technical Information of China (English)

    林华; 郑瑞强; 吴晓燕; 於江泉; 卢年芳; 邵俊; 王海霞

    2012-01-01

    Objective To investigate the guiding significance of pulse indicator continuous cardiac output(PICCO) for the fluid resuscitation in elderly patients with septic shock. Methods Twenty-four elderly patients with septic shock were divided into observation group and control group,twelve cases in each group. The patients in observation group were treated with fluid resuscitation under the guidance of PICCO monitor, while the patients in control group were treated with fluid resuscitation under the guidance of monitoring central venous pressure, then the curative effect was compared between the two groups. Results On the first day of treatment, there was no statistical difference in the blood cell and neutrophil counts, mixed venous oxygen saturation ( SvO2) ,the levels of procalcitonin ( PCT) and lactic acid (LA) between the two groups (P >0. 05). On the second and third days of treatment, the white blood cell, neutrophil counts and the levels of LA and PCT in observation group were significantly lower than those in control group(P <0. 05) ,but SvO2 was significantly higher( P < 0. 05). Compared with control group,the mechanical ventilation time was significantly shorter(P <0. 05) , and the case fatality within 28 days was lower in observation group( P < 0.05 ). Conclusion PICCO monitor has important guiding significance in the treatment of fluid resuscitation in elderly patients with septic shock,which can significantly improve blood gas analysis index,shorten the mechanical ventilation time and reduce mortality.%目的 探讨脉搏指示连续心排血量(PICCO)监测技术对老年感染性休克液体复苏治疗的指导意义.方法 24例老年感染性休克患者分为观察组和对照组,每组12例.观察组患者在PICCO监护仪监测指导下补液治疗,对照组患者在监测中心静脉压指导下补液治疗;观察比较2组治疗效果.结果 治疗第1天,2组患者白细胞、中性粒细胞计数、混合静脉血氧饱和度(SvO2)、血降

  9. Exercise efficiency of low power output cycling.

    Science.gov (United States)

    Reger, M; Peterman, J E; Kram, R; Byrnes, W C

    2013-12-01

    Exercise efficiency at low power outputs, energetically comparable to daily living activities, can be influenced by homeostatic perturbations (e.g., weight gain/loss). However, an appropriate efficiency calculation for low power outputs used in these studies has not been determined. Fifteen active subjects (seven females, eight males) performed 14, 5-min cycling trials: two types of seated rest (cranks vertical and horizontal), passive (motor-driven) cycling, no-chain cycling, no-load cycling, cycling at low (10, 20, 30, 40 W), and moderate (50, 60, 80, 100, 120 W) power outputs. Mean delta efficiency was 57% for low power outputs compared to 41.3% for moderate power outputs. Means for gross (3.6%) and net (5.7%) efficiencies were low at the lowest power output. At low power outputs, delta and work efficiency values exceeded theoretical values. In conclusion, at low power outputs, none of the common exercise efficiency calculations gave values comparable to theoretical muscle efficiency. However, gross efficiency and the slope and intercept of the metabolic power vs mechanical power output regression provide insights that are still valuable when studying homeostatic perturbations.

  10. TOPOLOGY OPTIMIZATION OF MULTIPLE INPUTS AND MULTIPLE OUTPUTS COMPLIANT MECHANISMS

    Institute of Scientific and Technical Information of China (English)

    ZHANG Xianmin; OUYANG Gaofei; WANG Hua

    2007-01-01

    An optimal topology design method for multiple inputs and multiple outputs compliant micro-manipulation system is presented. Firstly, the topology design problem is posed in terms of a multiple inputs load and several specified output deflections. The compliance and stiffness of the system are expressed by the mutual potential energy and strain energy, respectively, which can be controlled by a multi-criteria objective function. Secondly, based on the optimality criteria method, a model solution algorithm is presented. Finally, a numerical example is presented to show the validity of the presented technique. The optimal topology of a 4 inputs and 4 outputs compliant mechanism is obtained by using the method, and the corresponding micro-positioning stage system is further designed.

  11. GaN Nanowire Arrays for High-Output Nanogenerators

    KAUST Repository

    Huang, Chi-Te

    2010-04-07

    Three-fold symmetrically distributed GaN nanowire (NW) arrays have been epitaxially grown on GaN/sapphire substrates. The GaN NW possesses a triangular cross section enclosed by (0001), (2112), and (2112) planes, and the angle between the GaN NW and the substrate surface is ∼62°. The GaN NW arrays produce negative output voltage pulses when scanned by a conductive atomic force microscope in contact mode. The average of piezoelectric output voltage was about -20 mV, while 5-10% of the NWs had piezoelectric output voltages exceeding -(0.15-0.35) V. The GaN NW arrays are highly stable and highly tolerate to moisture in the atmosphere. The GaN NW arrays demonstrate an outstanding potential to be utilized for piezoelectric energy generation with a performance probably better than that of ZnO NWs. © 2010 American Chemical Society.

  12. Long-term monitoring of airborne nickel (Ni) pollution in association with some potential source processes in the urban environment.

    Science.gov (United States)

    Kim, Ki-Hyun; Shon, Zang-Ho; Mauulida, Puteri T; Song, Sang-Keun

    2014-09-01

    The environmental behavior and pollution status of nickel (Ni) were investigated in seven major cities in Korea over a 13-year time span (1998-2010). The mean concentrations of Ni measured during the whole study period fell within the range of 3.71 (Gwangju: GJ) to 12.6ngm(-3) (Incheon: IC). Although Ni values showed a good comparability in a relatively large spatial scale, its values in most cities (6 out of 7) were subject to moderate reductions over the study period. To assess the effect of major sources on the long-term distribution of Ni, the relationship between their concentrations and the potent source processes like non-road transportation sources (e.g., ship and aircraft emissions) were examined from some cities with port and airport facilities. The potential impact of long-range transport of Asian dust particles in controlling Ni levels was also evaluated. The overall results suggest that the Ni levels were subject to gradual reductions over the study period irrespective of changes in such localized non-road source activities. The pollution of Ni at all the study sites was maintained well below the international threshold (Directive 2004/107/EC) value of 20ngm(-3).

  13. Spectral Reflectance and Vegetation Index Changes in Deciduous Forest Foliage Following Tree Removal: Potential for Deforestation Monitoring

    Science.gov (United States)

    Peng, D.; Hu, Y.; Li, Z.

    2016-05-01

    It is important to detect and quantify deforestation to guide strategic decisions regarding environment, socioeconomic development, and climate change. In the present study, we conducted a field experiment to examine spectral reflectance and vegetation index changes in poplar and locust tree foliage with different leaf area indices over the course of three sunny days, following tree removal from the canopy. The spectral reflectance of foliage from harvested trees was measured using an ASD FieldSpec Prospectroradiometer; synchronous meteorological data were also obtained. We found that reflectance in short-wave infrared and red-edge reflectance was more time sensitive after tree removal than reflectance in other spectral regions, and that the normalized difference water index (NDWI) and the red-edge chlorophyll index (CIRE) were the preferred indicators of these changes from several indices evaluated. Synthesized meteorological environments were found to influence water and chlorophyll contents after tree removal, and this subsequently changed the spectral canopy reflectance. Our results indicate the potential for such tree removal to be detected with NDWI or CIRE from the second day of a deforestation event.

  14. Conflict and performance monitoring throughout the lifespan: An event-related potential (ERP) and temporospatial component analysis.

    Science.gov (United States)

    Clawson, Ann; Clayson, Peter E; Keith, Cierra M; Catron, Christina; Larson, Michael J

    2017-03-01

    Cognitive control includes higher-level cognitive processes used to evaluate environmental conflict. Given the importance of cognitive control in regulating behavior, understanding the developmental course of these processes may contribute to a greater understanding of normal and abnormal development. We examined behavioral (response times [RTs], error rates) and event-related potential data (N2, error-related negativity [ERN], correct-response negativity [CRN], error positivity [Pe]) during a flanker task in cross-sectional groups of 45 youth (ages 8-18), 52 younger adults (ages 20-28), and 58 older adults (ages 56-91). Younger adults displayed the most efficient processing, including significantly reduced CRN and N2 amplitude, increased Pe amplitude, and significantly better task performance than youth or older adults (e.g., faster RTs, fewer errors). Youth displayed larger CRN and N2, attenuated Pe, and significantly worse task performance than younger adults. Older adults fell either between youth and younger adults (e.g., CRN amplitudes, N2 amplitudes) or displayed neural and behavioral performance that was similar to youth (e.g., Pe amplitudes, error rates). These findings point to underdeveloped neural and cognitive processes early in life and reduced efficiency in older adulthood, contributing to poor implementation and modulation of cognitive control in response to conflict. Thus, cognitive control processing appears to reach peak performance and efficiency in younger adulthood, marked by improved task performance with less neural activation.

  15. Comparison of bispectral index and composite auditory evoked potential index for monitoring depth of hypnosis in children.

    Science.gov (United States)

    Blussé van Oud-Alblas, Heleen J; Peters, Jeroen W B; de Leeuw, Tom G; Tibboel, Dick; Klein, Jan; Weber, Frank

    2008-05-01

    In pediatric patients, the Bispectral Index (BIS), derived from the electroencephalogram, and the composite A-Line autoregressive index (cAAI), derived from auditory evoked potentials and the electroencephalogram, have been used as measurements of depth of hypnosis during anesthesia. The performance and reliability of BIS and cAAI in distinguishing different hypnotic states in children, as evaluated with the University of Michigan Sedation Scale, were compared. Thirty-nine children (aged 2-16 yr) scheduled to undergo elective inguinal hernia surgery were studied. For all patients, standardized anesthesia was used. Prediction probabilities of BIS and cAAI versus the University of Michigan Sedation Scale and sensitivity/specificity were calculated. Prediction probabilities for BIS and cAAI during induction were 0.84 for both and during emergence were 0.75 and 0.74, respectively. At loss of consciousness, the median BIS remained unaltered (94 to 90; not significant), whereas cAAI values decreased (60 to 43; P hypnosis in children. Both indices, however, showed considerable overlap for different clinical conditions.

  16. Caste ratios affect the reproductive output of social trematode colonies.

    Science.gov (United States)

    Kamiya, T; Poulin, R

    2013-03-01

    Intraspecific phenotypic diversification in social organisms often leads to formation of physical castes which are morphologically specialized for particular tasks within the colony. The optimal caste allocation theory argues that specialized morphological castes are efficient at specific tasks, and hence different caste ratios should affect the ergonomic efficiency, hence reproductive output of the colony. However, the reproductive output of different caste ratios has been documented in few species of insects with equivocal support for the theory. This study investigated whether the ratios of nonreproductive and reproductive morphs affect the reproductive output of a recently discovered social trematode, Philophthalmus sp., in which the nonreproductive members are hypothesized to be defensive specialists. A census of natural infections and a manipulative in vitro experiment demonstrated a positive association between the reproductive output of trematode colonies and the ratio of nonreproductive to reproductive morphs in the presence of an intra-host trematode competitor, Maritrema novaezealandensis. On the contrary, without the competitor, reproductive output was negatively associated with the proportion of nonreproductive castes in colonies. Our findings demonstrate for the first time a clear fitness benefit associated with the nonreproductive castes in the presence of a competitor while illustrating the cost of maintaining such morphs in noncompetitive situations. Although the proximate mechanisms controlling caste ratio remain unclear in this trematode system, this study supports the prediction that the fitness of colonies is influenced by the composition of specialized functional morphs in social organisms, suggesting a potential for adaptive shifts of caste ratios over evolutionary time.

  17. Noninvasive cardiac output determination using applanation tonometry-derived radial artery pulse contour analysis in critically ill patients

    DEFF Research Database (Denmark)

    Compton, Friederike; Wittrock, Marc; Schaefer, Juergen-Heiner

    2008-01-01

    Conventional thermodilution cardiac output (CO) monitoring is limited mainly to intensive care units and operating rooms because it requires the use of invasive techniques. To reduce the potential for complications and to broaden the applicability of hemodynamic monitoring, noninvasive methods...... for CO determination are being sought. Applanation tonometry allows noninvasive CO estimation through pulse contour analysis, but the method has not been evaluated in critically ill patients. We therefore performed noninvasive radial artery applanation tonometry in 49 critically ill medical intensive...... care unit patients and compared CO estimates to invasive CO measurements obtained using a pulmonary artery catheter or the PiCCO transpulmonary thermodilution system. One-hundred-sixteen measurements were performed, and patients were receiving vasopressor support during 78 measurements. When the data...

  18. Development of monitoring techniques for potential seepage of CO2 from sub-seafloor storage sites: Field studies at Sleipner, North Sea

    Science.gov (United States)

    James, R. H.; Connelly, D. P.; Bull, J. M.; Lichtschlag, A.; Cevatoglu, M.; Le Bas, T.; Wright, I. C.

    2012-12-01

    Although CO2 has been stored at the Sleipner site in the North Sea for over 15 years, and a number of other sub-seafloor storage sites are now either in operation or planned, almost nothing is known about the effect of potential seepage on marine ecosystems. To address this, we will undertake a comprehensive field campaign to Sleipner (RRS James Cook Cruise 77) in September 2012 that aims to: (i) Constrain the potential pathways of seepage from the storage site. (ii) Test methods for the detection of seepage, including formation fluids, natural gas and CO2, as it passes through the sedimentary overburden and into the water column. (iii) Develop a monitoring strategy suitable for all offshore carbon capture and storage projects. To this end, we will conduct an extensive AUV survey in the vicinity of the sub-seafloor CO2 plume, using our novel, long-range AUTOSUB system. AUTOSUB will be equipped with a variety of instrumentation, including sidescan sonar and an EM2000 multibeam systems, as well as a CHIRP profiler capable of inspecting the architecture of the sedimentary overburden at unprecedented spatial resolution. Other instrumentation will include a series of sensors (including a pH sensor), to detect and monitor the dispersion of potential seepage, and a new colour camera. Areas of interest, revealed by the AUV surveys, will be inspected and sampled using a hybrid remotely operated vehicle, equipped with high resolution video cameras, a grab sampling device, and instrumentation for the collection of precisely-located water samples. Further water samples will be collected using the ship-based CTD system. Fluid and gas seeps will be sampled using a vibrocoring system, and analyses of the porefluid chemistry will be used to quantify fluxes across the sediment-seawater interface, and the source, transformation, and fate of dissolved constituents. Longer-term monitoring will be addressed by deployment of a seafloor lander, that is equipped with a flow meter, a

  19. Rare sugar D-allulose: Potential role and therapeutic monitoring in maintaining obesity and type 2 diabetes mellitus.

    Science.gov (United States)

    Hossain, Akram; Yamaguchi, Fuminori; Matsuo, Tatsuhiro; Tsukamoto, Ikuko; Toyoda, Yukiyasu; Ogawa, Masahiro; Nagata, Yasuo; Tokuda, Masaaki

    2015-11-01

    Obesity and type 2 diabetes mellitus (T2DM) are the leading worldwide risk factors for mortality. The inextricably interlinked pathological progression from excessive weight gain, obesity, and hyperglycemia to T2DM, usually commencing from obesity, typically originates from overconsumption of sugar and high-fat diets. Although most patients require medications, T2DM is manageable or even preventable with consumption of low-calorie diet and maintaining body weight. Medicines like insulin, metformin, and thiazolidinediones that improve glycemic control; however, these are associated with weight gain, high blood pressure, and dyslipidemia. These situations warrant the attentive consideration of the role of balanced foods. Recently, we have discovered advantages of a rare sugar, D-allulose, a zero-calorie functional sweetener having strong anti-hyperlipidemic and anti-hyperglycemic effects. Study revealed that after oral administration in rats D-allulose readily entered the blood stream and was eliminated into urine within 24h. Cell culture study showed that D-allulose enters into and leaves the intestinal enterocytes via glucose transporters GLUT5 and GLUT2, respectively. In addition to D-allulose's short-term effects, the characterization of long-term effects has been focused on preventing commencement and progression of T2DM in diabetic rats. Human trials showed that D-allulose attenuates postprandial glucose levels in healthy subjects and in borderline diabetic subjects. The anti-hyperlipidemic effect of D-allulose, combined with its anti-inflammatory actions on adipocytes, is beneficial for the prevention of both obesity and atherosclerosis and is accompanied by improvements in insulin resistance and impaired glucose tolerance. Therefore, this review presents brief discussions focusing on physiological functions and potential benefits of D-allulose on obesity and T2DM.

  20. Monitoring the Genotoxic and Cytotoxic Potential and the Presence of Pesticides and Hydrocarbons in Water of the Sinos River Basin, Southern Brazil.

    Science.gov (United States)

    Bianchi, Eloisa; Lessing, Gustavo; Brina, Karisa Roxo; Angeli, Larissa; Andriguetti, Natália Bordin; Peruzzo, Jaqueline Regina Soares; do Nascimento, Carlos Augusto; Spilki, Fernando Rosado; Ziulkoski, Ana Luiza; da Silva, Luciano Basso

    2017-04-01

    The Sinos River is one of the most polluted rivers in Brazil. The purpose of this work was to monitor the presence of some pesticides and hydrocarbons as well as the genotoxic and cytotoxic potential on HEp-2 cells from water samples collected at seven sites in the Sinos River Basin (SRB), southern Brazil. Nine samples were taken from the three main rivers in the SRB and used as a solution to dilute the HEp-2 cell culture medium after microfiltration. Twenty-four pesticides and 19 hydrocarbons were measured. Cytotoxicity was assessed by methyl thiazolyl tetrazolium (MTT) and neutral red (NR) assays, in which cells were exposed to different concentrations of the water samples for 24 h. Genotoxicity of the microfiltrated raw water samples was assessed by comet assay after 6 and 24 h of exposure. Among the chemicals analyzed, only the 2,4-D, dichloromethane, tetrachloroethene, chloroform, bromodichloromethane, styrene, and toluene were detected, but they were all lower than the limit established by Brazilian regulations. Twenty samples from a total of 60 had a cytotoxic effect in the MTT assay and 30 in the NR assay. The comet assay indicated the presence of genotoxic substances in the water at the seven locations monitored. Temporal and spatial variation was observed in the cytotoxicity and genotoxicity assays. Results indicated that the water in all stretches of the SRB is contaminated and it can cause harmful effects to humans and to the aquatic biota. This HEp-2 cell-line approach can be an additional tool for environmental monitoring.

  1. Hurricane related flooding monitoring: a method to delineate potentially affected areas by using a GIS model in the Caribbean area

    Science.gov (United States)

    Melelli, L.; Taramelli, A.; Sorichetta, A.; Pasqui, M.

    2007-12-01

    This research integrates the concept that the subject of natural hazards and the use of existing remote sensing systems in the different phases of a disaster management for a specific hurricane hazard, is based on the applicability of GIS model for increasing preparedness and providing early warning. The modelling of an hurricane event in potentially affected areas by GIS has recently become a major topic of research. In this context the disastrous effects of hurricanes on coastal communities and surroundings areas are well known, but there is a need to better understand the causes and the hazards contributions of the different events related to an hurricane, like storm surge, flooding and high winds. This blend formed the basis of a semi- quantitative and promising approach in order to model the spatial distribution of the final hazard along the affected areas. The applied model determines a sudden onset zoning from a set of available parameters starting from topography based on Shuttle Radar Topography Mission (SRTM) data. From the Digital Elevation Model as a first step the river network is derived and then classified based on the Strahler order account as proportional to flooding area. Then we use a hydrologic model that uses the wetness index (a parameter of specific catchment area defined as upslope area per unit contour length) to better quantify the drainage area that contributes to the flooded events. Complementary data for the final model includes remote sensed density rain dataset for the hurricane events taking into account and existing hurricane tracks inventories together with hurricane structure model (different buffers related to wind speed hurricane parameters in a GIS environment). To assess the overall susceptibility, the hazard results were overlaid with population dataset and landcover. The approach, which made use of a number of available global data sets, was then validated on a regional basis using past experience on hurricane frequency

  2. Assessment of respiratory output in mechanically ventilated patients.

    Science.gov (United States)

    Laghi, Franco

    2005-06-01

    Mechanically ventilated patients are subject to few pathophysiologic disturbances that have such intuitive importance as abnormal function of the respiratory output. Abnormal function of the respiratory output plays a fundamental role in all aspects of mechanical ventilation: in determining which patients require mechanical ventilation, in determining the interaction between a patient and the ventilator, and in determining when a patient can tolerate discontinuation of mechanical ventilation. Monitoring indexes such as the rate of rise in electrical activity of the diaphragm, Po.1, (dP/dt)max, and Pmus, has provided insight into the performance of the respiratory centers in critically ill patients, but these methods require considerable refinement. A large body of research on measurements of energy expenditure of the respiratory muscles, such as pressure-time product, and measurements of inspiratory effort, such as the tension-time index, is currently accumulating. Several challenges, however, lay ahead regarding these indices. First, there is the need to identify the correct level of pressure generation and respiratory muscle effort that should be attained in the day-to-day management of mechanically ventilated patients. The correct titration of ventilator setting should not cause iatrogenic muscle damage because the support is excessive or insufficient. One of the challenges in reaching this goal is that for the same patient, different underlying pathologic conditions (eg, sepsis or ventilator-associated muscle injury) may require different levels of support. Second, many of the measurements of pressure generation and effort have been confined to the research laboratory. Modifications of the technology to achieve accurate measurements in the intensive care unit-outside of the research laboratory--are needed. To facilitate individual titration of ventilator settings, the new technologies must provide easier access to quantification of drive, pressure output, and

  3. Self-potential and passive seismic monitoring of hydrothermal activity: A case study at Iodine Pool, Waimangu geothermal valley, New Zealand

    Science.gov (United States)

    Legaz, A.; Revil, A.; Roux, P.; Vandemeulebrouck, J.; Gouédard, P.; Hurst, T.; Bolève, A.

    2009-01-01

    Iodine geyser, located in the Waimangu Geothermal Valley (New Zealand), has been studied by both passive electrical and seismic methods. The activity of the geyser was monitored at various distances from the vent using self-potential method. The self-potential signals display cyclic negative variations with respect to a baseline drawn when the geyser is quiet. The minimum in the self-potential signals coincides with the maximum overflow. We provide a numerical model able to explain both the polarity and magnitude of the observed signal. This model is based on the fluctuations of the hydraulic head in the conduit of the geyser; the divergence of the streaming current density is created at the interface between the pipe and the surrounding rock. Passive seismic experiments were used to localize ambient noise sources. These signals have been processed with the so-called Matched-Field Processing technique (MFP); a dominant source emerged from this processing, that we characterized in range and depth with a good accuracy.

  4. Environmental monitoring to the sources of atmospheric emission by the Trad-MCN bioassay and analysis of the accumulative potential for uranium and fluoride

    Energy Technology Data Exchange (ETDEWEB)

    Machado, Alessandra C.F.E., E-mail: alessandra@ctmsp.mar.mil.b [Centro Tecnologico da Marinha em Sao Paulo (CTMSP), SP (Brazil). Div. de Monitoracao Ambiental; Ramos, Monique M.B., E-mail: monique@ctmsp.mar.mil.b [Centro Tecnologico da Marinha em Sao Paulo (CTMSP), SP (Brazil). Div. de Analise de Seguranca; Alves, Edenise S., E-mail: ealves@ibot.sp.gov.b [Instituto de Botanica de Sao Paulo, Sao Paulo, SP (Brazil). Secao de Anatomia

    2009-07-01

    The biomonitoring of the atmospheric contamination constitutes important procedure for adoption of environmental control measures. Biological assays have been employed to evaluate genotoxic agents in the atmosphere. The Tradescantia-micronucleus (Trad-MCN) assay has been extensively used in environmental monitoring owing to its efficiency in the detection of chromosomic damages in cytological preparations of easy execution. In this study we tested the viability of use of Trad-MCN with Tradescantia pallida cv. Purpurea for environmental monitoring in the Experimental Center Aramar (CEA), in Ipero - SP and its leaf accumulation capacity. The plants were exposed in situ, in flower-beds or flowerpots, established close to the sources of atmospheric emission. The bioassay was accomplished according to the usual protocol. The micronucleus frequencies were compared using the variance Kruskal-Wallis test. The obtained results indicated that the biomonitoring model adopted was not the ideal for the CEA, considering that the plant suffered the influence of climatic condition. However the plant showed to have accumulative potential for uranium. (author)

  5. ESTIMATION AND ANALYSIS OF OUTPUT GAP: AN APPLICATION OF STRUCTURAL VECTOR AUTOREGRESSION AND HODRICK-PRESCOTT-FMETHODS

    Directory of Open Access Journals (Sweden)

    Saeed Dehghan Khavari

    2012-01-01

    Full Text Available In this study we examined output gap in the Iranian economy. The main question of the study is that how much is seasonal output gap in Iranian Economy and which factor affects gap variation. The other question is that whether using HP-F as a statistical based method for estimating output gap, provide different result than using SVAR as theory based method. Accordingly the aim of study is to estimate potential output and thus output gap using two method and analysis of the result. We used two methods (Hodrick-Prescott Filter and SVAR to estimate quarterly output gap for the period 1988:1-2008:4. The results pointed out that the estimation is not sensitive to the method and there is a close relation between oil revenue and output gap. In the period of 1998:3-1999:3, when oil price reduced to $11.45 per barrel, Iranian economy faced with a recession and it affected on output gap with a lag. Output gap increased from 34818 in 2004:1-76782 million dollars in 2008: 4. The comparison of estimated output gap and changes of oil price in different periods point out the positive relation. According to the estimations of output gap, output gap in the Iranian Economy has intense fluctuation due to the effects of oil proceeds fluctuations. In some years, actual output is more than potential output, that is, output gap is positive and so this situation can be an important reason for inflation in that period and policy maker must do plans and policies for control of inflation and in some years, actual output is less than potential output and this means output gap was negative. This situation is a reason for unemployment in these years and therefore policy makers must do expansionary policies.

  6. Practice Output in College Language Classroom

    Institute of Scientific and Technical Information of China (English)

    张岩

    2010-01-01

    <正>Practice output constitutes an indispensable part in second language learning.Relevant theories like"Interface Position"and"Comprehensible Output"are discussed in order to analyze in detail how this practice can actually facilitate acquisition and finally pave the way for communicative output—a goal all language learners are striving for.

  7. DIST/AVC Out-Put Definition.

    Science.gov (United States)

    Wilkinson, Gene L.

    The first stage of development of a management information system for DIST/AVC (Division of Instructional Technology/Audio-Visual Center) is the definition of out-put units. Some constraints on the definition of output units are: 1) they should reflect goals of the organization, 2) they should reflect organizational structure and procedures, and…

  8. The Role of Output in Grammar Learning

    Institute of Scientific and Technical Information of China (English)

    尹莉; 段薇; 谢璐

    2014-01-01

    In China, English teachers tend to emphasize a lot on the importance of grammar learning because knowledge of gram⁃mar is the base of the competence of communication. This thesis just focuses on how output affects students ’grammar learning by analyzing the role of output in learning of English and the strategies of English learning.

  9. Multi-output programmable quantum processor

    OpenAIRE

    Yu, Yafei; Feng, Jian; Zhan, Mingsheng

    2002-01-01

    By combining telecloning and programmable quantum gate array presented by Nielsen and Chuang [Phys.Rev.Lett. 79 :321(1997)], we propose a programmable quantum processor which can be programmed to implement restricted set of operations with several identical data outputs. The outputs are approximately-transformed versions of input data. The processor successes with certain probability.

  10. THE NONSTATIONARITY OF GERMAN AGGREGATE OUTPUT

    NARCIS (Netherlands)

    ZELHORST, D; DEHAAN, J

    1993-01-01

    In this paper the stationarity of German per capita output for the period 1870-1989 is examined, using both a parametric and a non-parametric approach. The standard unit root tests and the scaled variogram suggest that German output is not stationary. Following the approach suggested by Perron (1989

  11. Early-Transition Output Decline Revisited

    Directory of Open Access Journals (Sweden)

    Crt Kostevc

    2016-05-01

    Full Text Available In this paper we revisit the issue of aggregate output decline that took place in the early transition period. We propose an alternative explanation of output decline that is applicable to Central- and Eastern-European countries. In the first part of the paper we develop a simple dynamic general equilibrium model that builds on work by Gomulka and Lane (2001. In particular, we consider price liberalization, interpreted as elimination of distortionary taxation, as a trigger of the output decline. We show that price liberalization in interaction with heterogeneous adjustment costs and non-employment benefits lead to aggregate output decline and surge in wage inequality. While these patterns are consistent with actual dynamics in CEE countries, this model cannot generate output decline in all sectors. Instead sectors that were initially taxed even exhibit output growth. Thus, in the second part we consider an alternative general equilibrium model with only one production sector and two types of labor and distortion in a form of wage compression during the socialist era. The trigger for labor mobility and consequently output decline is wage liberalization. Assuming heterogeneity of workers in terms of adjustment costs and non-employment benefits can explain output decline in all industries.

  12. Output beam analysis of high power COIL

    Institute of Scientific and Technical Information of China (English)

    Deli Yu(于德利); Fengting Sang(桑凤亭); Yuqi Jin(金玉奇); Yizhu Sun(孙以珠)

    2003-01-01

    As the output power of a chemical oxygen iodine laser (COIL) increases, the output laser beam instabilityappears as the far-field beam spot drift and deformation for the large Fresnel number unstable resonator.In order to interpret this phenomenon, an output beam mode simulation code was developed with the fastFourier transform method. The calculation results show that the presence of the nonuniform gain in COILproduces a skewed output intensity distribution, which causes the mirror tilt and bulge due to the thermalexpansion. With the output power of COIL increases, the mirror surfaces, especially the back surface ofthe scraper mirror, absorb more and more heat, which causes the drift and deformation of far field beamspot seriously. The initial misalignment direction is an important factor for the far field beam spot driftingand deformation.

  13. Crop Insurance, Premium Subsidy and Agricultural Output

    Institute of Scientific and Technical Information of China (English)

    XU Jing-feng; LIAO Pu

    2014-01-01

    This paper studied the effects of crop insurance on agricultural output with an economic growth model. Based on Ramsey-Cass-Koopmans (RCK) model, a basic model of agriculture economic growth was developed. Extending the basic model to incorporate uncertainty and insurance mechanism, a risk model and a risk-insurance model were built to study the inlfuences of risk and crop insurance on agricultural output. Compared with the steady states of the three models, the following results are achieved:(i) agricultural output decreases if we introduce uncertainty into the risk-free model;(ii) crop insurance promotes agriculture economic growth if insurance mechanism is introduced into the risk model;(iii) premium subsidy constantly improves agricultural output. Our contribution is that we studied the effects of crop insurance and premium subsidy from the perspective of economic growth in a dynamic framework, and proved the output promotion of crop insurance theoretically.

  14. Qualification and application of a surface plasmon resonance-based assay for monitoring potential HAHA responses induced after passive administration of a humanized anti Lewis-Y antibody.

    Science.gov (United States)

    Szolar, O H J; Stranner, S; Zinoecker, I; Mudde, G C; Himmler, G; Waxenecker, G; Nechansky, A

    2006-06-16

    A sensitive, surface plasmon resonance (SPR)-based assay monitoring potential human-anti-human antibody (HAHA) reactions against the monoclonal antibody (mAb) IGN311 is presented. The latter is a fully humanized Lewis-Y carbohydrate specific mAb that is currently tested in a passive immune therapy approach in a clinical phase I trial. For the SPR experiments a BIACORE 3000 analyzer was used. The ligand IGN311 was covalently coupled to the carboxy-methylated dextran matrix of a CM5 research grade chip (BIACORE). In the course of a fully nested experimental design, a four parameter logistic equation was identified as appropriate calibration model ranging from 0.3 microg/mL (lower limit of quantitation, LLOQ) to 200 microg/mL (upper limit of quantitation, ULOQ) using an anti-idiotypic mAb ('HAHA mimic') as calibrator. The bias ranged from -2.4% to 5.5% and the intermediate precision expressed as 95% CI revealed values from 5.6% to 8.3%. Specificity was evaluated using six human serum matrices from healthy donors spiked with calibrator at the limit of quantitation (LOQ) with >80% of values being recovered with less than 25% relative error. The qualified assay was applied to monitor potentially induced HAHA reactivity in 11 patients from a clinical phase I trial with passively administered IGN311. Of the 11 patients, one high HAHA responder and several low responders were identified. Protein-G depletion experiments with human serum samples revealed that the observed response is predominantly caused by IgG binding to the ligand. The characteristics of these HAHA responses were all of the so-called 'Type I' which is defined by a peak response around day 15 that decreases from this point steadily suggesting that some kind of tolerance is established. Therefore, this type of HAHA response is regarded as non critical for the patient's safety.

  15. A high energy output nanogenerator based on reduced graphene oxide

    Science.gov (United States)

    Li, Weiping; Zhang, Yupeng; Liu, Liangliang; Li, Delong; Liao, Lei; Pan, Chunxu

    2015-10-01

    In this paper, we report a novel graphene-based nanogenerator for high energy harvesting. Experimental and theoretical results revealed that the energy output mechanism is the joint action of the strain effect (band engineering) and the triboelectric effect of reduced graphene oxide. It was found that the current could be adjusted by experimental parameters, such as the electrolyte concentration and rotation rate. Furthermore, the voltage output could be amplified by series connection of the system. Compared with other nanogenerators, the present graphene-based nanogenerator provides advantages, such as simple assembly, flexibility and high structural stability. It is expected that this nanogenerator will be of potential application in active sensors and sustainable power sources.In this paper, we report a novel graphene-based nanogenerator for high energy harvesting. Experimental and theoretical results revealed that the energy output mechanism is the joint action of the strain effect (band engineering) and the triboelectric effect of reduced graphene oxide. It was found that the current could be adjusted by experimental parameters, such as the electrolyte concentration and rotation rate. Furthermore, the voltage output could be amplified by series connection of the system. Compared with other nanogenerators, the present graphene-based nanogenerator provides advantages, such as simple assembly, flexibility and high structural stability. It is expected that this nanogenerator will be of potential application in active sensors and sustainable power sources. Electronic supplementary information (ESI) available. See DOI: 10.1039/c5nr04971g

  16. On the Potential Uses of Static Offsets Derived From Low-Cost Community Instruments and Crowd-Sourcing for Earthquake Monitoring and Rapid Response

    Science.gov (United States)

    Minson, S. E.; Brooks, B. A.; Murray, J. R.; Iannucci, R. A.

    2013-12-01

    We explore the efficacy of low-cost community instruments (LCCIs) and crowd-sourcing to produce rapid estimates of earthquake magnitude and rupture characteristics which can be used for earthquake loss reduction such as issuing tsunami warnings and guiding rapid response efforts. Real-time high-rate GPS data are just beginning to be incorporated into earthquake early warning (EEW) systems. These data are showing promising utility including producing moment magnitude estimates which do not saturate for the largest earthquakes and determining the geometry and slip distribution of the earthquake rupture in real-time. However, building a network of scientific-quality real-time high-rate GPS stations requires substantial infrastructure investment which is not practicable in many parts of the world. To expand the benefits of real-time geodetic monitoring globally, we consider the potential of pseudorange-based GPS locations such as the real-time positioning done onboard cell phones or on LCCIs that could be distributed in the same way accelerometers are distributed as part of the Quake Catcher Network (QCN). While location information from LCCIs often have large uncertainties, their low cost means that large numbers of instruments can be deployed. A monitoring network that includes smartphones could collect data from potentially millions of instruments. These observations could be averaged together to substantially decrease errors associated with estimated earthquake source parameters. While these data will be inferior to data recorded by scientific-grade seismometers and GPS instruments, there are features of community-based data collection (and possibly analysis) that are very attractive. This approach creates a system where every user can host an instrument or download an application to their smartphone that both provides them with earthquake and tsunami warnings while also providing the data on which the warning system operates. This symbiosis helps to encourage

  17. Monitoring and remediation of on-farm and off-farm ground current measured as step potential on a Wisconsin dairy farm: A case study.

    Science.gov (United States)

    Stetzer, Dave; Leavitt, Adam M; Goeke, Charles L; Havas, Magda

    2016-01-01

    Ground current commonly referred to as "stray voltage" has been an issue on dairy farms since electricity was first brought to rural America. Equipment that generates high-frequency voltage transients on electrical wires combined with a multigrounded (electrical distribution) system and inadequate neutral returns all contribute to ground current. Despite decades of problems, we are no closer to resolving this issue, in part, due to three misconceptions that are addressed in this study. Misconception 1. The current standard of 1 V at cow contact is adequate to protect dairy cows; Misconception 2. Frequencies higher than 60 Hz do not need to be considered; and Misconception 3. All sources of ground current originate on the farm that has a ground current problem. This case study of a Wisconsin dairy farm documents, 1. how to establish permanent monitoring of ground current (step potential) on a dairy farm; 2. how to determine and remediate both on-farm and off-farm sources contributing to step potential; 3. which step-potential metrics relate to cow comfort and milk production; and 4. how these metrics relate to established standards. On-farm sources include lighting, variable speed frequency drives on motors, radio frequency identification system and off-farm sources are due to a poor primary neutral return on the utility side of the distribution system. A step-potential threshold of 1 V root mean square (RMS) at 60 Hz is inadequate to protect dairy cows as decreases of a few mV peak-peak at higher frequencies increases milk production, reduces milking time and improves cow comfort.

  18. Recommended methods for evaluating the benefits of ECUT Program outputs. [Energy Conversion and Utilization

    Energy Technology Data Exchange (ETDEWEB)

    Levine, L.O.; Winter, C.

    1986-03-01

    This study was conducted to define and develop techniques that could be used to assess the complete spectrum of positive effects resulting from the Energy Conversion and Utilization Technologies (ECUT) Program activities. These techniques could then be applied to measure the benefits from past ECUT outputs. In addition, the impact of future ECUT outputs could be assessed as part of an ongoing monitoring process, after sufficient time has elapsed to allow their impacts to develop.

  19. Output Regulation of the Arneodo Chaotic System

    Directory of Open Access Journals (Sweden)

    Sundarapandian Vaidyanathan

    2010-08-01

    Full Text Available This paper solves the problem of regulating the output of the Arneodo chaotic system (1981, which is one of the paradigms of chaotic dynamical systems. Explicitly, using the state feedback control laws, the output of the Arneodo chaotic system is regulated so as to track constant reference signals as well as to track periodic reference signals. The control laws are derived using the regulator equations of Byrnes and Isidori (1990, which provide the solution of the output regulation problem for nonlinear control systems involving neutrally stable exosystem dynamics. Numerical results are shown to verify the results.

  20. Design of hydraulic output Stirling engine

    Science.gov (United States)

    Toscano, W. M.; Harvey, A. C.; Lee, K.

    1983-01-01

    A hydraulic output system for the RE-1000 free piston stirling engine (FPSE) was designed. The hydraulic output system can be readily integrated with the existing hot section of RE-1000 FPSE. The system has two simply supported diaphragms which separate the engine gas from the hydraulic fluid, a dynamic balance mechanism, and a novel, null center band hydraulic pump. The diaphragms are designed to endure more than 10 billion cycles, and to withstand the differential pressure load as high as 14 MPa. The projected thermodynamic performance of the hydraulic output version of RE-1000 FPSE is 1.87 kW at 29/7 percent brake efficiency.

  1. Monitoring the hydrologic system for potential effects of geothermal and ground-water development in the Long Valley caldera, Mono County, California, U.S.A.

    Science.gov (United States)

    Farrar, C.D.; Lyster, D. L.

    1990-01-01

    In the early 1980's, renewed interest in the geothermal potential of the Long Valley caldera, California, highlighted the need to balance the benefits of energy development with the established recreational activities of the area. The Long Valley Hydrologic Advisory Committee, formed in 1987, instituted a monitoring program to collect data during the early stages of resource utilization to evaluate potential effects on the hydrologic system. Early data show declines in streamflow, spring flow, and ground-water levels caused by 6 years of below-average precipitation. Springs in the Hot Creek State Fish Hatchery area discharge water that is a mixture of nonthermal and hydrothermal components. Possible sources of nonthermal water have been identified by comparing deuterium concentrations in streams and springs. The equivalent amount of undiluted thermal water discharged from the springs was calculated on the basis of boron and chloride concentrations. Quantifying the thermal and nonthermal fractions of the total flow may allow researchers to assess changes in flow volume or temperature of the springs caused by groundwater or geothermal development.

  2. Monitoring of the antiviral potential of bee venom and wax extracts against Adeno-7 (DNA) and Rift Valley fever virus (RNA) viruses models.

    Science.gov (United States)

    Hassan, Mostafa I; Mohamed, Aly F; Amer, Moner A; Hammad, Kotb M; Riad, Saber A

    2015-04-01

    This study monitored the antiviral potential of bee venom and four wax extracts, ethanol white and black beeswax (EWW/EBW) and acetone white and black beeswax (AWW/ABW) extracts. Two different virus models namely Adeno-7 as DNA model and RVFV as RNA virus models. End point calculation assay was used to calculate virus depletion titer. The depletion of viral infectivity titer of ABW to Adeno-7 virus showed strong antiviral activity recorded a depletion of viral infectivity titer (1.66 log (10)/ ml) that gave equal action with bee venom and more than interferon IFN (1 log (10)/ ml). On the other hand, antiviral activity of EBW showed a moderate potential, while AWW showed no antiviral activity. Finally EWW showed synergetic activity against Adeno-7 virus activity. Thus, activity of wax extracts to RVFV was arranged in order of IFN bee venom > AWW & EBW > EWW and ABW recorded 3.34, 0.65, 0.5, 0.34 respectively. It is the first time to study the beeswax effect against DNA and RNA virus' models; acetone black beeswax recorded a depletion titer 1.66 log (10)/ml.

  3. Neural response dynamics of spiking and local field potential activity depend on CRT monitor refresh rate in the tree shrew primary visual cortex.

    Science.gov (United States)

    Veit, Julia; Bhattacharyya, Anwesha; Kretz, Robert; Rainer, Gregor

    2011-11-01

    Entrainment of neural activity to luminance impulses during the refresh of cathode ray tube monitor displays has been observed in the primary visual cortex (V1) of humans and macaque monkeys. This entrainment is of interest because it tends to temporally align and thus synchronize neural responses at the millisecond timescale. Here we show that, in tree shrew V1, both spiking and local field potential activity are also entrained at cathode ray tube refresh rates of 120, 90, and 60 Hz, with weakest but still significant entrainment even at 120 Hz, and strongest entrainment occurring in cortical input layer IV. For both luminance increments ("white" stimuli) and decrements ("black" stimuli), refresh rate had a strong impact on the temporal dynamics of the neural response for subsequent luminance impulses. Whereas there was rapid, strong attenuation of spikes and local field potential to prolonged visual stimuli composed of luminance impulses presented at 120 Hz, attenuation was nearly absent at 60-Hz refresh rate. In addition, neural onset latencies were shortest at 120 Hz and substantially increased, by ∼15 ms, at 60 Hz. In terms of neural response amplitude, black responses dominated white responses at all three refresh rates. However, black/white differences were much larger at 60 Hz than at higher refresh rates, suggesting a mechanism that is sensitive to stimulus timing. Taken together, our findings reveal many similarities between V1 of macaque and tree shrew, while underscoring a greater temporal sensitivity of the tree shrew visual system.

  4. Marketing Outputs as Art? Bringing an Aesthetic Sensibility to the Marketing Curriculum

    Science.gov (United States)

    Petkus, Ed, Jr.; Budeva, Desislava; Chung, Christina; Dzhogleva, Hristina

    2011-01-01

    Can marketing outputs--advertising, packaging, product design, and retail environments--be considered a form of art? This paper explores the potential for incorporating the theories and concepts of aesthetics in the marketing curriculum in order to facilitate students' capacity to interpret marketing outputs and develop effective practical…

  5. Marketing Outputs as Art? Bringing an Aesthetic Sensibility to the Marketing Curriculum

    Science.gov (United States)

    Petkus, Ed, Jr.; Budeva, Desislava; Chung, Christina; Dzhogleva, Hristina

    2011-01-01

    Can marketing outputs--advertising, packaging, product design, and retail environments--be considered a form of art? This paper explores the potential for incorporating the theories and concepts of aesthetics in the marketing curriculum in order to facilitate students' capacity to interpret marketing outputs and develop effective practical…

  6. Maximum Power Output of Quantum Heat Engine with Energy Bath

    CERN Document Server

    Liu, Shengnan

    2016-01-01

    The difference between quantum isoenergetic process and quantum isothermal process comes from the violation of the law of equipartition of energy in the quantum regime. To reveal an important physical meaning of this fact, here we study a special type of quantum heat engine consisting of three processes: isoenergetic, isothermal and adiabatic processes. Therefore, this engine works between the energy and heat baths. Combining two engines of this kind, it is possible to realize the quantum Carnot engine. Furthermore, considering finite velocity of change of the potential shape, here an infinite square well with moving walls, the power output of the engine is discussed. It is found that the efficiency and power output are both closely dependent on the initial and final states of the quantum isothermal process. The performance of the engine cycle is shown to be optimized by control of the occupation probability of the ground state, which is determined by the temperature and the potential width. The relation betw...

  7. The use of interim data and Data Monitoring Committee recommendations in randomized controlled trial reports: frequency, implications and potential sources of bias

    Directory of Open Access Journals (Sweden)

    Hampton John

    2008-03-01

    Full Text Available Abstract Background Interim analysis of accumulating trial data is important to protect participant safety during randomized controlled trials (RCTs. Data Monitoring Committees (DMCs often undertake such analyses, but their widening role may lead to extended use of interim analysis or recommendations that could potentially bias trial results. Methods Systematic search of eight major publications: Annals of Internal Medicine, BMJ, Circulation, CID, JAMA, JCO, Lancet and NEJM, including all randomised controlled trials (RCTs between June 2000 and May 2005 to identify RCTs that reported use of interim analysis, with or without DMC involvement. Recommendations made by the DMC or based on interim analysis were identified and potential sources of bias assessed. Independent double data extraction was performed on all included trials. Results We identified 1772 RCTs, of which 470 (27%; 470/1772 reported the use of a DMC and a further 116 (7%; 116/1772 trials reported some form of interim analysis without explicit mention of a DMC. There were 28 trials (24 with a formal DMC, randomizing a total of 79396 participants, identified as recommending changes to the trial that may have lead to biased results. In most of these, some form of sample size re-estimation was recommended with four trials also reporting changes to trial endpoints. The review relied on information reported in the primary publications and methods papers relating to the trials, higher rates of use may have occurred but not been reported. Conclusion The reported use of interim analysis and DMCs in clinical trials has been increasing in recent years. It is reassuring that in most cases recommendations were made in the interest of participant safety. However, in practice, recommendations that may lead to potentially biased trial results are being made.

  8. Genetic expression of adipose derived stem cell and smooth muscle cell markers to monitor differentiation potential following low intensity laser irradiation

    Science.gov (United States)

    Abrahamse, Heidi

    2014-02-01

    Mesenchymal stem cells (MSCs) have the capacity to differentiate into a variety of cell types that could potentially be used in tissue engineering and regenerative medicine. Low intensity laser irradiation (LILI) has been shown to induce a significant increase in cell viability and proliferation. Growth factors such as retinoic acid (RA) and transforming growth factor β1 (TGF-β1) play important roles in the differentiation of cells. The aim of this study was to investigate whether LILI in combination with growth factors could induce the differentiation of adipose derived stem cells (ADSCs) cocultured with smooth muscle cells (SMCs). The study used primary and continuous ADSC cell lines and a SMC line (SKUT-1) as control. Cells were co-cultured directly at a ratio of 1:1 using established methods, with and without growth factors and then exposed to LILI at 5 J/cm2 using a 636 nm diode laser. The cellular morphology, viability and proliferation of the co-cultures were assessed over a period of one week. The study also monitored the expression of cell specific markers over the same period of time. Genetic expression of the markers for both adipose derived stem cells (β1 Integrin and Thymidine 1) and smooth muscle cells (Heavy Myosin Chain) was monitored using flow cytometry. Cell viability and proliferation increased significantly in the co-cultured groups that were exposed to laser alone, as well as in combination with growth factors. Furthermore, there was a significant decrease in the expression of stem cell markers in the ADSCs over time. The results indicate that LILI in combination with growth factors not only increases the viability and proliferation of co-cultured cells but also decreases the expression of ADSC stem cell markers. This could indicate the possible differentiation of ADSCs into SMCs.

  9. Investigation of the Influence of the As-Grown ZnO Nanorods and Applied Potentials on an Electrochemical Sensor for In-Vitro Glucose Monitoring

    Directory of Open Access Journals (Sweden)

    Mohammed Marie

    2017-01-01

    Full Text Available The influence of the as-grown zinc oxide nanorods (ZnO NRs on the fabricated electrochemical sensor for in vitro glucose monitoring were investigated. A direct growth of ZnO NRs was performed on the Si/SiO2/Au electrode, using hydrothermal and sol-gel techniques at low temperatures. The structure, consisting of a Si/SiO2/Au/GOx/Nafion membrane, was considered as a baseline, and it was tested under several applied potential 0.1–0.8 V. The immobilized working electrode, with GOx and a nafion membrane, was characterized amperometrically using a source meter Keithely 2410, and an electrochemical impedance Gamry potentiostat. The sensor exhibited the following: a high sensitivity of ~0.468 mA/cm2 mM, a low detection limit in the order of 166.6 µM, and a fast and sharp response time of around 2 s. The highest sensitivity and the lowest limit of detection were obtained at 0.4 volt, after the growth of ZnO NRs. The highest net sensitivity was obtained after subtracting the sensitivity of the baseline, and it was in the order of 0.315 mA/cm2·mM. The device was tested with a range of glucose concentrations from 1–10 mM, showing a linear line from 3–8 mM, and the device was saturated after exceeding high concentrations of glucose. Such devices can be used for in vitro glucose monitoring, since glucose changes can be accurately detected.

  10. Investigating the potential for long-term permeable reactive barrier (PRB) monitoring from the electrical signatures associated with the reduction in reactive iron performance

    Energy Technology Data Exchange (ETDEWEB)

    Slater, Lee D.; Korte, N.; Baker, J.

    2005-12-14

    The objective of this work was to conduct laboratory and field experiments to determine the sensitivity of low frequency electrical measurements (resistivity and induced polarization) to the processes of corrosion and precipitation that are believed to limit permeable reactive barrier (PRB) performance. The research was divided into four sets of experiments that were each written up and submitted to a peer-reviewed journal: [1] A laboratory experiment to define the controls of aqueous chemistry (electrolyte activity; pH; valence) and total zero valent iron (Fe0) available surface area on the electrical properties of Fe0 columns. [2] A laboratory experiment to determine the impact of corrosion and precipitation on the electrical response of synthetic Fe0 columns as a result of geochemical reactions with NaSO4 and NaCO3 electrolytes. [3] Laboratory experiments on a sequence of cores retrieved from the Kansas City PRB to determine the magnitude of electrical and geochemical changes within a field active PRB after eight years of operation [4] Field-scale cross borehole resistivity and induced polarization monitoring of the Kansas City PRB to evaluate the potential of electrical imaging as a technology for non-invasive, long-term monitoring of indicators of reduced PRB performance This report first summarizes the findings of the four major experiments conducted under this research. The reader is referred to the four papers in Appendices 1-4 for a full description of each experiment, including motivation and significance, technical details, findings and implications. The deliverables of the project, including the publications, conference papers and new collaborative arrangements that have resulted are then described. Appendices 5-6 contain two technical reports written by co-PI Korte describing (1) supporting geochemical measurements, and (2) the coring procedure, conducted at the Kansas City PRB as part of this project.

  11. Acute exposure to fenthion in juveniles of white cachama (Piaractus brachypomus: toxic effects, changes in cholinesterase activity and potential use in environmental monitoring

    Directory of Open Access Journals (Sweden)

    Borbón Javier F.

    2012-03-01

    Full Text Available Fenthion is an organophosphate insecticide used worldwide that may pollute waters after itsapplication causing potential problems in public health and poisoning in domestic and wildlifeanimals. Objective: to evaluate toxic effects, butyrylcholinesterase activity (BChE and use inenvironmental monitoring, 34 juveniles of white cachama (Piaractus brachypomus were distributedin 3 groups (control, 0,13 ppm and 2 ppm fenthion for 96 h. Materials and methods: fishwere exposed in 10-gallon tanks; symptoms, gross lesions post-mortem, viscerosomatic index(VSI and plasma BChE activity were evaluated. Mean comparisons for each variable amongtreatments were performed (ANOVA, α=0,05. Results: severe signs were seen in 3 specimens(3/11 of 2 ppm fenthion between 11 and 34 h of exposure. These signs were frantic swimming,muscle tremors and loss of swimming axis. In 0,13 ppm, mild to moderate signs (tremors andcaudal fin flapping were observed in some of the fish. The VSI (control = 5,3 ± 0,5; 0,13 ppm= 6,9 ± 0,3 and 2 ppm = 7,3 ± 0,6 was significantly different between exposed to fenthion andcontrols. BChE activity (control = 185,0 ± 20,4; 0,13 ppm = 12,5 ± 2,3 and 2 ppm = 9,8 ± 1,8nmoles / ml plasma / min showed significant inhibition in exposed to fenthion as compared tocontrols. Conclusions: the present work confirmed the toxic effects of fenthion in white cachamajuveniles. Results found in BChE activity suggest its use in environmental monitoring as a goodbiomarker of organophosphates waterborne exposure.

  12. Memory-based parallel data output controller

    Science.gov (United States)

    Stattel, R. J.; Niswander, J. K. (Inventor)

    1984-01-01

    A memory-based parallel data output controller employs associative memories and memory mapping to decommutate multiple channels of telemetry data. The output controller contains a random access memory (RAM) which has at least as many address locations as there are channels. A word counter addresses the RAM which provides as it outputs an encoded peripheral device number and a MSB/LSB-first flag. The encoded device number and a bit counter address a second RAM which contains START and STOP flags to pick out the required bits from the specified word number. The LSB/MSB, START and STOP flags, along with the serial input digital data go to a control block which selectively fills a shift register used to drive the parallel data output bus.

  13. THE MALARIA BURDEN AND AGRICULTURAL OUTPUT IN ...

    African Journals Online (AJOL)

    iya beji

    monetary policy can be used to stimulate agricultural output even if only in the .... require higher lags than could be accommodated given the number of our data .... Time Series with a Unit Root”, Journal of the American Statistical Association,.

  14. Scaling of global input-output networks

    Science.gov (United States)

    Liang, Sai; Qi, Zhengling; Qu, Shen; Zhu, Ji; Chiu, Anthony S. F.; Jia, Xiaoping; Xu, Ming

    2016-06-01

    Examining scaling patterns of networks can help understand how structural features relate to the behavior of the networks. Input-output networks consist of industries as nodes and inter-industrial exchanges of products as links. Previous studies consider limited measures for node strengths and link weights, and also ignore the impact of dataset choice. We consider a comprehensive set of indicators in this study that are important in economic analysis, and also examine the impact of dataset choice, by studying input-output networks in individual countries and the entire world. Results show that Burr, Log-Logistic, Log-normal, and Weibull distributions can better describe scaling patterns of global input-output networks. We also find that dataset choice has limited impacts on the observed scaling patterns. Our findings can help examine the quality of economic statistics, estimate missing data in economic statistics, and identify key nodes and links in input-output networks to support economic policymaking.

  15. OFFSHORE OIL OUTPUT MORE THAN SCHEDULED

    Institute of Scientific and Technical Information of China (English)

    1997-01-01

    @@ China Offshore Oil Nan Hai East Corp (CONHE) is one of four subsidiaries of the China National Offshore Oil Corp.The first-quarter output was an encouraging 220 000 tons more than the planned goal for that period.

  16. Oil Refining Giants to Cut Output

    Institute of Scientific and Technical Information of China (English)

    Zhang Dingmin

    2002-01-01

    @@ China's refined oil product output rose slightly in the first five months of this year on strong demand,but the two biggest domestic producers plan to cut production rates in an attempt to bolster the sluggish price.

  17. Coupling output of multichannel high power microwaves

    Science.gov (United States)

    Li, Guolin; Shu, Ting; Yuan, Chengwei; Zhang, Jun; Yang, Jianhua; Jin, Zhenxing; Yin, Yi; Wu, Dapeng; Zhu, Jun; Ren, Heming; Yang, Jie

    2010-12-01

    The coupling output of multichannel high power microwaves is a promising technique for the development of high power microwave technologies, as it can enhance the output capacities of presently studied devices. According to the investigations on the spatial filtering method and waveguide filtering method, the hybrid filtering method is proposed for the coupling output of multichannel high power microwaves. As an example, a specific structure is designed for the coupling output of S/X/X band three-channel high power microwaves and investigated with the hybrid filtering method. In the experiments, a pulse of 4 GW X band beat waves and a pulse of 1.8 GW S band microwave are obtained.

  18. Output Measures and Library Space Planning.

    Science.gov (United States)

    Lushington, Nolan

    1987-01-01

    Draws some initial connections between library performance measures and library space planning and collection management. Output measure surveys are suggested for establishing hierarchies of use and appropriate design of environments for housing the collection. Four references are listed. (MES)

  19. Enhanced output entanglement with reservoir engineering

    OpenAIRE

    Yan, Xiao-Bo

    2017-01-01

    We study the output entanglement in a three-mode optomechanical system via reservoir engineering by shifting the center frequency of filter function away from resonant frequency. We find the bandwidth of the filter function can suppress the entanglement in the vicinity of resonant frequency of the system, while the entanglement will become prosperous if the center frequency departs from the resonant frequency. We obtain the approximate analytical expressions of the output entanglement, and fr...

  20. APPROXIMATE OUTPUT REGULATION FOR AFFINE NONLINEAR SYSTEMS

    Institute of Scientific and Technical Information of China (English)

    Yali DONG; Daizhan CHENG; Huashu QIN

    2003-01-01

    Output regulation for affine nonlinear systems driven by an exogenous signal is investigated in this paper. In the absence of the standard exosystem hypothesis, we assume availability of the instantaneous values of the exogenous signal and its first time-derivative for use in the control law.For affine nonlinear systems, the necessary and sufficient conditions of the solvability of approximate output regulation problem are obtained. The precise form of the control law is presented under some suitable assumptions.

  1. PMN-PT/PVDF Nanocomposite for High Output Nanogenerator Applications

    Directory of Open Access Journals (Sweden)

    Chuan Li

    2016-04-01

    Full Text Available The 0.7Pb(Mg1/3Nb2/3O3-0.3PbTiO3(0.7PMN-0.3PT nanorods were obtained via hydrothermal method with high yield (over 78%. Then, new piezoelectric nanocomposites based on (1−xPb(Mg1/3Nb2/3O3-xPbTiO3 (PMN-PT nanorods were fabricated by dispersing the 0.7PMN-0.3PT nanorods into piezoelectric poly(vinylidene fluoride (PVDF polymer. The mechanical behaviors of the nanocomposites were investigated. The voltage and current generation of PMN-PT/PVDF nanocomposites were also measured. The results showed that the tensile strength, yield strength, and Young’s modulus of nanocomposites were enhanced as compared to that of the pure PVDF. The largest Young’s modulus of 1.71 GPa was found in the samples with 20 wt % nanorod content. The maximum output voltage of 10.3 V and output current of 46 nA were obtained in the samples with 20 wt % nanorod content, which was able to provide a 13-fold larger output voltage and a 4.5-fold larger output current than that of pure PVDF piezoelectric polymer. The current density of PMN-PT/PVDF nanocomposites is 20 nA/cm2. The PMN-PT/PVDF nanocomposites exhibited great potential for flexible self-powered sensing applications.

  2. PMN-PT/PVDF Nanocomposite for High Output Nanogenerator Applications.

    Science.gov (United States)

    Li, Chuan; Luo, Wenbo; Liu, Xingzhao; Xu, Dong; He, Kai

    2016-04-11

    The 0.7Pb(Mg1/3Nb2/3)O₃-0.3PbTiO₃(0.7PMN-0.3PT) nanorods were obtained via hydrothermal method with high yield (over 78%). Then, new piezoelectric nanocomposites based on (1-x)Pb(Mg1/3Nb2/3)O₃-xPbTiO₃ (PMN-PT) nanorods were fabricated by dispersing the 0.7PMN-0.3PT nanorods into piezoelectric poly(vinylidene fluoride) (PVDF) polymer. The mechanical behaviors of the nanocomposites were investigated. The voltage and current generation of PMN-PT/PVDF nanocomposites were also measured. The results showed that the tensile strength, yield strength, and Young's modulus of nanocomposites were enhanced as compared to that of the pure PVDF. The largest Young's modulus of 1.71 GPa was found in the samples with 20 wt % nanorod content. The maximum output voltage of 10.3 V and output current of 46 nA were obtained in the samples with 20 wt % nanorod content, which was able to provide a 13-fold larger output voltage and a 4.5-fold larger output current than that of pure PVDF piezoelectric polymer. The current density of PMN-PT/PVDF nanocomposites is 20 nA/cm². The PMN-PT/PVDF nanocomposites exhibited great potential for flexible self-powered sensing applications.

  3. Features on various monitoring methods for laser welding and their application. 2. Appearances of detective signals with changes of basic welding conditions; Laser yosetsu no tame no monitoring ho no tokucho to sono oyo. 2. Kihon yosetsu joken no henka ni tomonau kakushu keisoku shingo no henka

    Energy Technology Data Exchange (ETDEWEB)

    Matsunawa, A. [Osaka University, Osaka (Japan); Watanabe, M.; Nakabayashi, T.; Hiraga, H.; Inoue, T.

    1998-05-05

    Studies are in progress on elucidating behavior of laser induced plasma during laser welding, and on monitoring of welding characteristics. This paper describes an investigation on changes in such signals as light emission, sound, and plasma potential when such processing conditions as processing speed and laser output are varied. It also discusses applicability of the laser behavior to monitoring, as a result of having the plasma behavior elucidation study moved forward by one step. Correlation with weld penetration appeared remarkably stronger in average amplitude than in average output in both of the light emitting intensity and the plasma potential. The fact that the average amplitude and the light emission have correlation is largely affected by change in vibration morphology of metal plasma due to the effect of penetrating conditions such as sizes of key hole and molten pool. Furthermore, in change of signal output due to change in the laser output, considerations must be given on relational elements between the output change in the beam as an energy supply source for turning laser into plasma. The average amplitude in the measurement signal for the plasma potential may be used as a monitoring parameter for processing speed and processing output. 13 refs., 9 figs., 1 tab.

  4. ATLAS Fast Physics Monitoring: TADA

    CERN Document Server

    Elsing, Markus; The ATLAS collaboration; Sabato, Gabriele; Kamioka, Shusei; Nairz, Armin Michael; Moyse, Edward; Gumpert, Christian

    2016-01-01

    The ATLAS Experiment at the LHC is recording data from proton-proton collisions with 13 TeV center-of-mass energy since spring 2015. The collaboration is using a fast physics monitoring framework (TADA) to automatically perform a broad range of fast searches for early signs of new physics and to monitor the data quality across the year with the full analysis level calibrations applied to the rapidly growing data. TADA is designed to provide fast feedback directly after the collected data has been fully calibrated and processed at the Tier-0. The system can monitor a large range of physics channels, offline data quality and physics performance quantities nearly final analysis level object calibrations. TADA output is available on a website accessible by the whole collaboration that gets updated twice a day with the data from newly processed runs. Hints of potentially interesting physics signals or performance issues identified in this way are reported to be followed up by physics or combined performance groups...

  5. ATLAS Fast Physics Monitoring: TADA

    CERN Document Server

    Sabato, Gabriele; The ATLAS collaboration

    2017-01-01

    The ATLAS experiment at the LHC is recording data from proton-proton collisions with 13 TeV center-of-mass energy since spring 2015. The collaboration is using a fast physics monitoring framework (TADA) to automatically perform a broad range of fast searches for early signs of new physics and to monitor the data quality across the year with the full analysis level calibrations applied to the rapidly growing data.TADA is designed to provide fast feedback directly after the collected data has been fully calibrated and processed at the Tier-0, the CERN Data Center. The system can monitor a large range of physics channels, offline data quality and physics performance quantities nearly final analysis level object calibrations. TADA output is available on a website accessible by the whole collaboration that gets updated twice a day with the data from newly processed runs. Hints of potentially interesting physics signals or performance issues identified in this way are reported to be followed up by physics or combin...

  6. Evaluation of U.S. Geological Survey Monitoring-well network and potential effects of changes in water use, Newlands Project, Churchill County, Nevada

    Science.gov (United States)

    Maurer, Douglas K.; Seiler, Ralph L.; Watkins, Sharon A.

    2004-01-01

    Domestic wells tapping shallow ground water are an important source of potable water for rural residents of Lahontan Valley. For this reason, the public has expressed concern over the acquisition of water rights directed by Public Law 101-618. The acquisition has resulted in removal of land from irrigation, which could cause shallow domestic wells to go dry and adversely affect shallow ground-water quality. Periodic water-level measurements and water-quality sampling at a monitoring-well network developed by the U.S. Geological Survey (USGS) provided data to evaluate the potential effects of changes in water use. The USGS, in cooperation with Churchill County, analyzed these data and the monitoring-well network to determine if the network provides an adequate means to measure the response of the shallow aquifer to changes in water use, and to determine if measurable changes have taken place. To evaluate the USGS monitoring-well network, wells were characterized by their distance from active canals or ditches, and from currently (2003) or formerly irrigated land. An analysis of historical data showed that about 9,800 acres of land have been removed from irrigation, generally from the late 1990's to 2003. Twenty-five wells in the network are within about 1 mile of fields removed from irrigation. Of the 25 wells, 13 are within 300 feet of canals or ditches where seepage maintains stable water levels. The 13 wells likely are not useful for detecting changes caused by reductions in irrigation. The remaining 12 wells range from about 400 to 3,800 feet from the nearest canal and are useful for detecting continued changes from current reductions in irrigation. The evaluation showed that of the 75 wells in the network, only 8 wells are likely to be useful for detecting the effects of future (after 2003) reductions in irrigation. Water levels at most of the monitoring wells near irrigated land have declined from 1998 to 2003 because of drought conditions and below normal

  7. LIFE CLIMATREE project: A novel approach for accounting and monitoring carbon sequestration of tree crops and their potential as carbon sink areas

    Science.gov (United States)

    Stergiou, John; Tagaris, Efthimios; -Eleni Sotiropoulou, Rafaella

    2016-04-01

    Climate Change Mitigation is one of the most important objectives of the Kyoto Convention, and is mostly oriented towards reducing GHG emissions. However, carbon sink is retained only in the calculation of the forests capacity since agricultural land and farmers practices for securing carbon stored in soils have not been recognized in GHG accounting, possibly resulting in incorrect estimations of the carbon dioxide balance in the atmosphere. The agricultural sector, which is a key sector in the EU, presents a consistent strategic framework since 1954, in the form of Common Agricultural Policy (CAP). In its latest reform of 2013 (reg. (EU) 1305/13) CAP recognized the significance of Agriculture as a key player in Climate Change policy. In order to fill this gap the "LIFE ClimaTree" project has recently founded by the European Commission aiming to provide a novel method for including tree crop cultivations in the LULUCF's accounting rules for GHG emissions and removal. In the framework of "LIFE ClimaTree" project estimation of carbon sink within EU through the inclusion of the calculated tree crop capacity will be assessed for both current and future climatic conditions by 2050s using the GISS-WRF modeling system in a very fine scale (i.e., 9km x 9km) using RCP8.5 and RCP4.5 climate scenarios. Acknowledgement: LIFE CLIMATREE project "A novel approach for accounting and monitoring carbon sequestration of tree crops and their potential as carbon sink areas" (LIFE14 CCM/GR/000635).

  8. Seismic time-lapse monitoring of potential gas hydrate dissociation around boreholes : could it be feasible? A conceptual 2D study linking geomechanical and seismic FD models

    Energy Technology Data Exchange (ETDEWEB)

    Pecher, I.; Yang, J.; Anderson, R.; Tohidi, B.; MacBeth, C. [Heriot-Watt Univ., Edinburgh (United Kingdom). Inst. of Petroleum Engineering; Freij-Ayoub, R.; Clennell, B. [CSIRO Petroleum, Bentley, WA (Australia)

    2008-07-01

    Dissociation of gas hydrate to water and potentially overpressured gas around boreholes may pose a hazard for deep-water hydrocarbon production. Strategies to mitigate this risk include monitoring for early detection of dissociation. Seismic methods are especially promising, primarily because of a high sensitivity of P-wave velocity to gas in the pore space of unconsolidated sediments. This paper presented a study that applied commonly used rock physics modeling to predict the seismic response to gas hydrate dissociation with a focus on P-impedance and performed sensitivity tests. The geomechanical model was translated into seismic models. In order to determine which parameters needed to be particularly well calibrated in experimental and modeling studies, the sensitivity of seismic properties to a variation of input parameters was estimated. The seismic response was predicted from dissociating gas hydrates using two-dimensional finite-difference wave-propagation modeling to demonstrate that despite the small predicted lateral extent of hydrate dissociation, its pronounced effect on seismic properties should allow detection with a seismic source on a drilling platform and receivers on the seafloor. The paper described the methods, models, and results of the study. It was concluded that the key factors for predicting the seismic response of sediments to hydrate dissociation were the mode of gas hydrate distribution, gas distribution in the sediments, gas saturation, and pore pressure. 33 refs., 3 tabs., 8 figs.

  9. Movement-related cortical activation with voluntary pinch task: simultaneous monitoring of near-infrared spectroscopy signals and movement-related cortical potentials

    Science.gov (United States)

    Sato, Yosuke; Fukuda, Masafumi; Oishi, Makoto; Fujii, Yukihiko

    2012-07-01

    This study was designed to evaluate hemodynamic and electrophysiological motor cortex responses to voluntary finger pinching in humans, with simultaneous recording of near-infrared spectroscopy (NIRS) signals and movement-related cortical potentials (MRCP). Six healthy, right-handed subjects performed 100 trials of voluntary right-thumb index-finger pinching with about a 10-second interval at their own pace. Throughout the session, 48 regions over the bilateral motor cortex were assessed by NIRS, while MRCP and electromyogram (EMG) were simultaneously monitored. MRCP started 1536+/-58 ms before EMG onset and peaked 127+/-24 ms after EMG onset. NIRS data showed bilateral prefrontal cortex at 0.5+/-0.1 s before EMG onset and bilateral dorsal premotor cortex activations at 0.6+/-0.1 s before EMG onset. The hand area of the sensorimotor cortex was activated left-dominantly, seen obviously peaked at 3.7+/-0.2 s after EMG onset. The comparison between MRCP and NIRS results raised the possibility that the vascular response to neural activity occurs within 4 s with a voluntary pinch task. These results indicate that our technique allows detailed study of the motor control. Our method is a promising strategy for event-related motor control and neurovascular coupling studies.

  10. Errors in the isotopic estimations of hepatic glycogen synthesis and glucose output

    Energy Technology Data Exchange (ETDEWEB)

    Rognstad, R.

    1989-07-01

    Ignoring the reality of glucose in equilibrium glucose-6P cycling in the liver in vivo produces large potential errors in the isotopic quantitation of percentage contributions of direct and indirect pathways of glycogen synthesis and of hepatic glucose output.

  11. Preparation and Application of Film Sensor for Metal Structure Crack Monitoring

    Directory of Open Access Journals (Sweden)

    Bo HOU

    2015-11-01

    Full Text Available A crack monitoring technique is desired to ensure the safety and reliability of metallic structures. In the present study, a conductive film sensor was presented to monitor structural cracks in metal structures in real-time based on the electrical potential method. First, a Ti/TiN film sensor was prepared on the fatigue critical portion of a 2A12-T4 aluminum alloy specimen by vacuum ion plating technology, which allows firm integration with the metal surface. A finite element model (FEM of the Ti/TiN film sensor was then constructed and the changes in the output of the sensor along with corresponding changes in crack propagation were discussed. The results indicated that the Ti/TiN film sensor has high sensitivity to cracks and it is feasible to monitor structural surface cracks using the sensor. Finally, crack monitoring experiments were carried out based on the Ti/TiN film sensor. Experimental results showed that the output potential curve of the Ti/TiN film sensor contained several regions, which corresponded to plastic deformation accumulation, crack propagation, and sensor failure, respectively. Therefore, the information on the origination and propagation of structural cracks can be gained through analyzing changes in slope of the output potential values of the Ti/TiN film sensor with respect to time.DOI: http://dx.doi.org/10.5755/j01.ms.21.4.9623

  12. Residual gravimetric method to measure nebulizer output.

    Science.gov (United States)

    Vecellio None, Laurent; Grimbert, Daniel; Bordenave, Joelle; Benoit, Guy; Furet, Yves; Fauroux, Brigitte; Boissinot, Eric; De Monte, Michele; Lemarié, Etienne; Diot, Patrice

    2004-01-01

    The aim of this study was to assess a residual gravimetric method based on weighing dry filters to measure the aerosol output of nebulizers. This residual gravimetric method was compared to assay methods based on spectrophotometric measurement of terbutaline (Bricanyl, Astra Zeneca, France), high-performance liquid chromatography (HPLC) measurement of tobramycin (Tobi, Chiron, U.S.A.), and electrochemical measurements of NaF (as defined by the European standard). Two breath-enhanced jet nebulizers, one standard jet nebulizer, and one ultrasonic nebulizer were tested. Output produced by the residual gravimetric method was calculated by weighing the filters both before and after aerosol collection and by filter drying corrected by the proportion of drug contained in total solute mass. Output produced by the electrochemical, spectrophotometric, and HPLC methods was determined after assaying the drug extraction filter. The results demonstrated a strong correlation between the residual gravimetric method (x axis) and assay methods (y axis) in terms of drug mass output (y = 1.00 x -0.02, r(2) = 0.99, n = 27). We conclude that a residual gravimetric method based on dry filters, when validated for a particular agent, is an accurate way of measuring aerosol output.

  13. Response requirements as constraints on output.

    Science.gov (United States)

    Zeiler, M D; Buchman, I B

    1979-07-01

    Two experiments studied how added response requirements affected fixed-interval schedule performance. Experiment 1 involved tandem fixed-interval fixed-ratio schedules, and Experiment 2 studied conjunctive fixed-interval fixed-ratio schedules. In both, pigeons' output, defined as overall response rate or as responses during the interval, first increased and then decreased as the ratio was raised. With small ratio requirements, the frequency of reinforcement in time either did not change or decreased slightly. With progressively larger ratios, reinforcement frequency decreased consistently. Alternative explanations were discussed. The first, a reinforcement theory account, was that response strength is an increasing monotonic function of both the response requirement and reinforcement frequency, and the bitonic output function represents interacting effects. Increases in the response requirement accompanied by small changes in reinforcement frequency enhance output, but further increases result in large enough decrements in reinforcement frequency so that output is lowered. The second explanation does not view reinforcement as a basic process but, instead, derives from concepts of economics and conservation. Organisms allocate their behavior among alternatives so as to maximize value, where value is a function of the responses that can occur in a given situation under the set of restrictions imposed by particular schedules. One form of this theory explicitly predicts that output is a bitonic function of ratio requirements in simple ratio schedules. However, it was not clear that this model could explain the present effects involving joint ratio and interval schedule restrictions.

  14. Output characteristics of Stirling thermoacoustic engine

    Energy Technology Data Exchange (ETDEWEB)

    Sun, Daming; Qiu, Limin; Wang, Bo; Xiao, Yong; Zhao, Liang [Institute of Refrigeration and Cryogenic Engineering, Zhejiang University, No. 38, Zheda Road, Hangzhou, Zhejiang 310027 (China)

    2008-05-15

    A thermoacoustic engine (TE), which converts thermal energy into acoustic power by the thermoacoustic effect, shows several advantages due to the absence of moving parts, such as high reliability and long lifetime associated with reduced manufacturing costs. Power output and efficiency are important criteria of the performance of a TE. In order to increase the acoustic power output and thermal efficiency of a Stirling TE, the acoustic power distribution in the engine is studied with the variable load method. It is found that the thermal efficiency is independent of the output locations along the engine under the same acoustic power output. Furthermore, when the pressure ratio is kept constant at one location along the TE, it is beneficial to increasing the thermal efficiency by exporting more acoustic power. With nitrogen of 2.5 MPa as working gas and the pressure ratio at the compliance of 1.20 in the experiments, the acoustic power is measured at the compliance and the resonator simultaneously. The maximum power output, thermal efficiency and exergy efficiency reach 390.0 W, 11.2% and 16.0%, which are increased by 51.4%, 24.4% and 19.4%, respectively, compared to those with a single R-C load with 750 ml reservoir at the compliance. This research will be instructive for increasing the efficiency and making full use of the acoustic energy of a TE. (author)

  15. Output characteristics of Stirling thermoacoustic engine

    Energy Technology Data Exchange (ETDEWEB)

    Sun Daming [Institute of Refrigeration and Cryogenic Engineering, Zhejiang University, No. 38, Zheda Road, Hangzhou, Zhejiang 310027 (China); Qiu Limin [Institute of Refrigeration and Cryogenic Engineering, Zhejiang University, No. 38, Zheda Road, Hangzhou, Zhejiang 310027 (China)], E-mail: limin.qiu@zju.edu.cn; Wang Bo; Xiao Yong; Zhao Liang [Institute of Refrigeration and Cryogenic Engineering, Zhejiang University, No. 38, Zheda Road, Hangzhou, Zhejiang 310027 (China)

    2008-05-15

    A thermoacoustic engine (TE), which converts thermal energy into acoustic power by the thermoacoustic effect, shows several advantages due to the absence of moving parts, such as high reliability and long lifetime associated with reduced manufacturing costs. Power output and efficiency are important criteria of the performance of a TE. In order to increase the acoustic power output and thermal efficiency of a Stirling TE, the acoustic power distribution in the engine is studied with the variable load method. It is found that the thermal efficiency is independent of the output locations along the engine under the same acoustic power output. Furthermore, when the pressure ratio is kept constant at one location along the TE, it is beneficial to increasing the thermal efficiency by exporting more acoustic power. With nitrogen of 2.5 MPa as working gas and the pressure ratio at the compliance of 1.20 in the experiments, the acoustic power is measured at the compliance and the resonator simultaneously. The maximum power output, thermal efficiency and exergy efficiency reach 390.0 W, 11.2% and 16.0%, which are increased by 51.4%, 24.4% and 19.4%, respectively, compared to those with a single R-C load with 750 ml reservoir at the compliance. This research will be instructive for increasing the efficiency and making full use of the acoustic energy of a TE.

  16. Maximum Power Output of Quantum Heat Engine with Energy Bath

    Directory of Open Access Journals (Sweden)

    Shengnan Liu

    2016-05-01

    Full Text Available The difference between quantum isoenergetic process and quantum isothermal process comes from the violation of the law of equipartition of energy in the quantum regime. To reveal an important physical meaning of this fact, here we study a special type of quantum heat engine consisting of three processes: isoenergetic, isothermal and adiabatic processes. Therefore, this engine works between the energy and heat baths. Combining two engines of this kind, it is possible to realize the quantum Carnot engine. Furthermore, considering finite velocity of change of the potential shape, here an infinite square well with moving walls, the power output of the engine is discussed. It is found that the efficiency and power output are both closely dependent on the initial and final states of the quantum isothermal process. The performance of the engine cycle is shown to be optimized by control of the occupation probability of the ground state, which is determined by the temperature and the potential width. The relation between the efficiency and power output is also discussed.

  17. An Analysis of Output on English Vocabulary Acquisition

    Institute of Scientific and Technical Information of China (English)

    曾娅妮

    2014-01-01

    Output Hypothesis was proposed by Swain in 1985, her Output Hypothesis is regarded as the most important and in-fluential one. However, few studies research and analyze the effect of output on vocabulary acquisition. The findings of this study suggest the importance of output in vocabulary acquisition. Furthermore, in the interactive mode output can help learners acquire vocabulary.

  18. Law of Conservation of the Capital-Output Ratio*

    Science.gov (United States)

    Samuelson, Paul A.

    1970-01-01

    Just as simple harmonic motion, definable by a variational condition, δ [unk] (½ ẋ2 - ½ x2) dt = 0, has motions which must conserve the sum of kinetic and potential energies, ½ ẋ2 + ½x2 ≅ constant, so in a neoclassical von Neumann economy, where all output is saved to provide capital formation for the system's growth, it will be true that there exists a conservation law—namely the constancy along any intertemporally-efficient motion of the capital-output ratio ΣPtjKtj/ΣPtjKt j. This is derived as an „energy” integral of a time-free integrand1 in an optimal-control problem of variational type. PMID:16591882

  19. An Introduction to Environmentally-Extended Input-Output Analysis

    Directory of Open Access Journals (Sweden)

    Justin Kitzes

    2013-09-01

    Full Text Available Environmentally-extended input-output (EEIO analysis provides a simple and robust method for evaluating the linkages between economic consumption activities and environmental impacts, including the harvest and degradation of natural resources. EEIO is now widely used to evaluate the upstream, consumption-based drivers of downstream environmental impacts and to evaluate the environmental impacts embodied in goods and services that are traded between nations. While the mathematics of input-output analysis are not complex, straightforward explanations of this approach for those without mathematical backgrounds remain difficult to find. This manuscript provides a conceptual and intuitive introduction to the goals of EEIO, the principles and mathematics behind EEIO analysis and the strengths and limitations of the EEIO approach. The wider adoption of EEIO approaches will help researchers and policy makers to better measure, and potentially decrease, the ultimate drivers of environmental degradation.

  20. Artificial Neural Networks to Predict the Power Output of a PV Panel

    Directory of Open Access Journals (Sweden)

    Valerio Lo Brano

    2014-01-01

    Full Text Available The paper illustrates an adaptive approach based on different topologies of artificial neural networks (ANNs for the power energy output forecasting of photovoltaic (PV modules. The analysis of the PV module’s power output needed detailed local climate data, which was collected by a dedicated weather monitoring system. The Department of Energy, Information Engineering, and Mathematical Models of the University of Palermo (Italy has built up a weather monitoring system that worked together with a data acquisition system. The power output forecast is obtained using three different types of ANNs: a one hidden layer Multilayer perceptron (MLP, a recursive neural network (RNN, and a gamma memory (GM trained with the back propagation. In order to investigate the influence of climate variability on the electricity production, the ANNs were trained using weather data (air temperature, solar irradiance, and wind speed along with historical power output data available for the two test modules. The model validation was performed by comparing model predictions with power output data that were not used for the network's training. The results obtained bear out the suitability of the adopted methodology for the short-term power output forecasting problem and identified the best topology.

  1. William Harvey, Peter Lauremberg and cardiac output.

    Science.gov (United States)

    Teichmann, G

    1992-11-01

    In 1636, the Rostock professor of medicine and the art of poetry, Peter Lauremberg (1585-1639), was one of the earliest to mention circulation which had been discovered by William Harvey and documented in his anatomical manual. In 1628 William Harvey proved the existence of the blood circulation by calculating the "cardiac output in a half an hour (semihora)". The answer to the question why Harvey chose half an hour as the time range can be found in the way of measuring time usual at that period. The sandglasses were turned half-hourly in maritime navigation and the wheel-clocks on shore had only the hour-hand. Improved chronometry was one of the prerequisites for measuring cardiac output. The minute-hand became usual after 1700 and the second-hand later on. Taking into consideration the alterations of cardiac output made the latter one of the most important circulation parameters in diagnostics, prognostication and therapeutics.

  2. Pole placement with constant gain output feedback

    Science.gov (United States)

    Sridhar, B.; Lindorff, D. P.

    1972-01-01

    Given a linear time invariant multivariable system with m inputs and p outputs, it was shown that p closed loop poles of the system can be preassigned arbitrarily using constant gain output feedback provided (A circumflex, B circumflex) is controllable. These data show that if (A circumflex, B circumflex, C circumflex) is controllable and observable, and Rank B circumflex = m, Rank C circumflex = p, then max (m,p) poles of the system can be assigned arbitarily using constant gain output feedback. Further, it is shown that in some cases more than max (m,p) poles can be arbitrarily assigned. A least square design technique is outlined to approximate the desired pole locations when it is not possible to place all the poles.

  3. PV output smoothing with energy storage.

    Energy Technology Data Exchange (ETDEWEB)

    Ellis, Abraham; Schoenwald, David Alan

    2012-03-01

    This report describes an algorithm, implemented in Matlab/Simulink, designed to reduce the variability of photovoltaic (PV) power output by using a battery. The purpose of the battery is to add power to the PV output (or subtract) to smooth out the high frequency components of the PV power that that occur during periods with transient cloud shadows on the PV array. The control system is challenged with the task of reducing short-term PV output variability while avoiding overworking the battery both in terms of capacity and ramp capability. The algorithm proposed by Sandia is purposely very simple to facilitate implementation in a real-time controller. The control structure has two additional inputs to which the battery can respond. For example, the battery could respond to PV variability, load variability or area control error (ACE) or a combination of the three.

  4. Effect of water intake on sweat output

    Directory of Open Access Journals (Sweden)

    K. V. Mani

    1961-07-01

    Full Text Available The effect of drinking volumes of water in excess of normal requirement at a given time on sweat output was studied under two conditions of body activity namely marching and standing, and two conditions of exposure namely sun and shade. It was found that (1drinking large volumes of water causes a significant and appreciable increase in sweat output, of the order of 0.8 gm/kg/hr; and (2 this increase is very nearly the same under all the conditions studied. It is suggested that changes in tonicity of the plasma may be the main cause for this phenomenon. It is also pointed out that this increased sweat output is not a loss to the body.

  5. Problems in Modelling Charge Output Accelerometers

    Directory of Open Access Journals (Sweden)

    Tomczyk Krzysztof

    2016-12-01

    Full Text Available The paper presents major issues associated with the problem of modelling change output accelerometers. The presented solutions are based on the weighted least squares (WLS method using transformation of the complex frequency response of the sensors. The main assumptions of the WLS method and a mathematical model of charge output accelerometers are presented in first two sections of this paper. In the next sections applying the WLS method to estimation of the accelerometer model parameters is discussed and the associated uncertainties are determined. Finally, the results of modelling a PCB357B73 charge output accelerometer are analysed in the last section of this paper. All calculations were executed using the MathCad software program. The main stages of these calculations are presented in Appendices A−E.

  6. Output radiation from a degenerate parametric oscillator

    CERN Document Server

    Tesfa, S

    2007-01-01

    We study the squeezing as well as the statistical properties of the output radiation from a degenerate parametric oscillator coupled to a squeezed vacuum reservoir employing the stochastic differential equations associated with the normal ordering. It is found that the degree of squeezing of the output radiation is less than the corresponding cavity radiation. However, for output radiation the correlation of the quadrature operators evaluated at different times also exhibits squeezing, which is the reason for quenching of the overall noise in one of the quadrature components of the squeezing spectrum even when the oscillator is coupled to a vacuum reservoir. Moreover, coupling the oscillator to the squeezed vacuum reservoir enhances the squeezing exponentially and it also increases the mean photon number.

  7. Output filters for AC adjustable speed drives

    DEFF Research Database (Denmark)

    Blaabjerg, Frede; Hanigovszki, Norbert; Landkildehus, Jorn, Jorn

    2007-01-01

    -phase applications the occurrence of common-mode (CM) voltage is inherent due to asymmetrical output pulses [1]. Consequently, several secondary effects arise at the inverter's output: high-frequency conducted and radiated emissions, leakage current, motor insulation stress due to wave reflection [2], bearing stress......The standard industrial solution for adjustable speed drives (ASD) is the use of induction motors (IM) fed by voltage-source inverters (VSI). The inverter generates a pulsewidth modulated (PWM) voltage, with dv/dt values of about 6 kV/¿s or even more. In three-leg inverters for three...

  8. Reliability and Energy Output of Bifacial Modules

    Energy Technology Data Exchange (ETDEWEB)

    Van Aken, B.B.; Jansen, M.J.; Dekker, N.J.J. [ECN Solar Energy, Petten (Netherlands)

    2013-06-15

    Although flash tests under standard test conditions yields lower power due to transmittance of the back sheet, bifacial modules are expected to outperform their monofacial equivalents in terms of yearly energy output in the field. We compare flash tests for bifacial modules with and without a light scattering panel directly behind the modules: 3% more power output is obtained. We also report on the damp-heat reliability of modules with transparent back sheet. Finally we will present the results of an outdoor study comparing modules with transparent back sheet and modules with state-of-the-art AR coating on the front glass.

  9. Input/Output Subroutine Library Program

    Science.gov (United States)

    Collier, James B.

    1988-01-01

    Efficient, easy-to-use program moved easily to different computers. Purpose of NAVIO, Input/Output Subroutine Library, provides input/output package of software for FORTRAN programs that is portable, efficient, and easy to use. Implemented as hierarchy of libraries. At bottom is very small library containing only non-portable routines called "I/O Kernel." Design makes NAVIO easy to move from one computer to another, by simply changing kernel. NAVIO appropriate for software system of almost any size wherein different programs communicate through files.

  10. Validation of a continuous, arterial pressure-based cardiac output measurement: a multicenter, prospective clinical trial.

    Science.gov (United States)

    McGee, William T; Horswell, Jeffrey L; Calderon, Joachim; Janvier, Gerard; Van Severen, Tom; Van den Berghe, Greet; Kozikowski, Lori

    2007-01-01

    The present study compared measurements of cardiac output by an arterial pressure-based cardiac output (APCO) analysis method with measurement by intermittent thermodilution cardiac output (ICO) via pulmonary artery catheter in a clinical setting. The multicenter, prospective clinical investigation enrolled patients with a clinical indication for cardiac output monitoring requiring pulmonary artery and radial artery catheters at two hospitals in the United States, one hospital in France, and one hospital in Belgium. In 84 patients (69 surgical patients), the cardiac output was measured by analysis of the arterial pulse using APCO and was measured via pulmonary artery catheter by ICO; to establish a reference comparison, the cardiac output was measured by continuous cardiac output (CCO). Data were collected continuously by the APCO and CCO technologies, and at least every 4 hours by ICO. No clinical interventions were made as part of the study. For APCO compared with ICO, the bias was 0.20 l/min, the precision was +/- 1.28 l/min, and the limits of agreement were -2.36 l/m to 2.75 l/m. For CCO compared with ICO, the bias was 0.66 l/min, the precision was +/- 1.05 l/min, and the limits of agreement were -1.43 l/m to 2.76 l/m. The ability of APCO and CCO to assess changes in cardiac output was compared with that of ICO. In 96% of comparisons, APCO tracked the change in cardiac output in the same direction as ICO. The magnitude of change was comparable 59% of the time. For CCO, 95% of comparisons were in the same direction, with 58% of those changes being of similar magnitude. In critically ill patients in the intensive care unit, continuous measurement of cardiac output using either APCO or CCO is comparable with ICO. Further study in more homogeneous populations may refine specific situations where APCO reliability is strongest.

  11. Brainstem auditory evoked potential monitoring and neuro-endoscopy: Two tools to ensure hearing preservation and surgical success during microvascular decompression

    Directory of Open Access Journals (Sweden)

    Cheng-Chia Lee

    2014-06-01

    Conclusion: The results of this retrospective study emphasized the importance of BAEP monitoring and neuro-endoscopy during MVD. It is well known that BAEP monitoring can preserve hearing function, and the endoscope offers neurosurgeons a second look to identify the nerve root entry zone and confirms the position of the Teflon felt. These two tools are especially useful in difficult cases.

  12. Improvements in determination of cardiac output with a Swan-Ganz catheter.

    Science.gov (United States)

    Sakagami, M; Kuwana, K; Nakanishi, H; Sakai, K

    1990-01-01

    The time constant for heat transfer may affect exact determination of cardiac output with Swan-Ganz catheters. Commercially available Swan-Ganz catheters are provided with thermistors with varying time constants. Current monitoring of cardiac output is not corrected for these time constants, so the conventional method of determining cardiac output using the equation of Stewart-Hamilton produces marked errors. The authors propose a new method of determining cardiac output with Swan-Ganz catheters with varying time constants from thermal dilution curve data based on Newton's cooling law. Values for blood flow rate determined by the new method using a completely stirred tank of original design, mimicking the natural heart and using bovine blood, are almost the same as values observed at varying saline infusion volumes, saline temperatures, and saline infusion times.

  13. Assessment of limits and potentials of SWOT data for inland water bodies characterization and monitoring based on simulated data: Application to the Yangtze river complex

    Science.gov (United States)

    Yesou, Herve; Blumstein, Denis; Uribe, C