Drug target mining and analysis of the Chinese tree shrew for pharmacological testing.

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Feng Zhao

Full Text Available The discovery of new drugs requires the development of improved animal models for drug testing. The Chinese tree shrew is considered to be a realistic candidate model. To assess the potential of the Chinese tree shrew for pharmacological testing, we performed drug target prediction and analysis on genomic and transcriptomic scales. Using our pipeline, 3,482 proteins were predicted to be drug targets. Of these predicted targets, 446 and 1,049 proteins with the highest rank and total scores, respectively, included homologs of targets for cancer chemotherapy, depression, age-related decline and cardiovascular disease. Based on comparative analyses, more than half of drug target proteins identified from the tree shrew genome were shown to be higher similarity to human targets than in the mouse. Target validation also demonstrated that the constitutive expression of the proteinase-activated receptors of tree shrew platelets is similar to that of human platelets but differs from that of mouse platelets. We developed an effective pipeline and search strategy for drug target prediction and the evaluation of model-based target identification for drug testing. This work provides useful information for future studies of the Chinese tree shrew as a source of novel targets for drug discovery research.

High shrew diversity on Alaska's Seward Peninsula: Community assembly and environmental change

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Hope, Andrew G.

2012-01-01

In September 2010, 6 species of shrews (genus: Sorex) were collected at a single locality on the Seward Peninsula of Alaska. Such high sympatric diversity within a single mammalian genus is seldom realized. This phenomenon at high latitudes highlights complex Arctic community dynamics that reflect significant turnover through time as a consequence of environmental change. Each of these shrew species occupies a broad geographic distribution collectively spanning the entire Holarctic, although the study site lies within Eastern Beringia, near the periphery of all individual ranges. A review of published genetic evidence reflects a depauperate shrew community within ice-free Beringia through the last glaciation, and recent assembly of current diversity during the Holocene.

Neurochemical characterization of the tree shrew dorsal striatum

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MATTHEW W RICE

2011-08-01

Full Text Available The striatum is a major component of the basal ganglia and is associated with motor and cognitive functions. Striatal pathologies have been linked to several disorders, including Huntington's, Tourette's syndrome, obsessive-compulsive disorders and schizophrenia. For the study of these striatal pathologies different animal models have been used, including rodents and non-human primates. Rodents lack on morphological complexity (for example, the lack of well defined caudate and putamen nuclei, which makes it difficult to translate data to the human paradigm. Primates, and especially higher primates, are the closest model to humans, but there are ever-increasing restrictions to the use of these animals for research. In our search for a non-primate animal model with a striatum that anatomically (and perhaps functionally can resemble that of humans, we turned our attention to the tree shrew. Evolutionary genetic studies have provided strong data supporting that the tree shrews (Scadentia are one of the closest groups to primates, although their brain anatomy has only been studied in detail for specific brain areas. Morphologically, the tree shrew striatum resembles the primate striatum with the presence of an internal capsule separating the caudate and putamen, but little is known about its neurochemical composition. Here we analyzed the expression of calcium-binding proteins, the presence and distribution of the striosome and matrix compartments (by the use of calbindin, tyrosine hydroxylase and acetylcholinesterase immunohistochemistry, and the GABAergic system by immunohistochemistry against glutamic acid decarboxylase and Golgi impregnation. In summary, our results show that when compared to primates, the tree shrew dorsal striatum presents striking similarities in the distribution of most of the markers studied, while presenting some marked divergences when compared to the rodent striatum.

Moles and Mole Control on British Farms, Amenities and Gardens after Strychnine Withdrawal

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Sandra E. Baker

2016-06-01

Full Text Available Moles are considered pests in Britain, but this issue has been little studied. Lower welfare standards have been tolerated for moles than for most other managed wild mammal species, as use of both the controversial poison, strychnine, and unregulated traps have been permitted. Strychnine was withdrawn in 2006 and there were fears that mole populations would increase as a result. In 2007, we conducted a comprehensive, nationwide survey of land manager perceptions, opinions and behaviour regarding moles and mole control on farms, amenities and domestic gardens in Britain. We surveyed 2150 land managers (achieving a 59% response rate and ground-truthed 29 responses. Moles were reported to be present on most farms and amenities, and 13% of gardens, and were more common in lighter soils. Where present, moles were usually considered pests, this being more likely in Wales, Scotland and northern England, on livestock and mixed farms, and on large, high-value amenities, e.g., racecourses and golf courses. Mole control followed similar patterns to mole presence. More control may occur than is economically, and therefore potentially ethically, justified. Control should be more carefully considered and, where necessary, more effectively targeted. Kill-trapping was the favoured recent and future method on farms and amenities, even if strychnine was to be reintroduced; however, because mole traps are currently unregulated, some might not meet current welfare standards if tested. We found no evidence for an increase in moles since a farm questionnaire survey conducted in 1992; this could have wider implications for future wildlife management policy changes.

Esterase variation in Turkish white-toothed shrews (Crocidura: Record of a trimeric esterase

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Tez C.

2009-01-01

Full Text Available This study focuses on esterase variation of the genus Crocidura in Turkey. A total of 248 white-toothed shrews were analyzed by means of cellulose acetate gel electrophoresis. Liver tissue and alfa naphthyl acetate were used to investigate esterase variation in Turkish white-toothed shrews. A different esterase banding pattern was found in one Crocidura individual. This phenotype had four anodally migrated bands on cellulose acetate gel. The Crocidura individual displaying the given phenotype was identified as Crocidura suaveolens. The different esterase banding pattern observed in this study is considered to be a result of the trimeric structure of esterase in the lesser white-toothed shrew (Crocidura suaveolens.

Identification and Characterization of Liver MicroRNAs of the Chinese Tree Shrew via Deep Sequencing.

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Feng, Yue; Feng, Yue-Mei; Feng, Yang; Lu, Caixia; Liu, Li; Sun, Xiaomei; Dai, Jiejie; Xia, Xueshan

2015-10-01

Chinese tree shrew (Tupaia belangeri chinensis) is a small animal that possess many features, which are valuable in biomedical research, as experimental models. Currently, there are numerous attempts to utilize tree shrews as models for hepatitis C virus (HCV) infection. This study aimed to construct a liver microRNA (miRNA) data of the tree shrew. Three second filial generation tree shrews were used in this study. Total RNA was extracted from each liver of the tree shrew and equal quality mixed, then reverse-transcribed to complementary DNA (cDNA). The cDNAs were amplified by polymerase chain reaction and subjected to high-throughput sequencing. A total of 2060 conserved miRNAs were identified through alignment with the mature miRNAs in miRBase 20.0 database. The gene ontology and Kyoto encyclopedia of genes and genomes analyses of the target genes of the miRNAs revealed several candidate miRNAs, genes and pathways that may involve in the process of HCV infection. The abundance of miR-122 and Let-7 families and their other characteristics provided us more evidences for the utilization of this animal, as a potential model for HCV infection and other related biomedical research. Moreover, 80 novel microRNAs were predicted using the software Mireap. The top 3 abundant miRNAs were validated in other tree samples, based on stem-loop quantitative reverse transcription-polymerase chain reaction. According to the liver microRNA data of Chinese tree shrew, characteristics of the miR-122 and Let-7 families further highlight the suitability of tree shrew as the animal model in HCV research.

Biodiversity and evolution of Imjin virus and Thottapalayam virus in Crocidurinae shrews in Zhejiang Province, China.

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Lin, Xian-Dan; Zhou, Run-Hong; Fan, Fei-Neng; Ying, Xu-Hua; Sun, Xiao-Yu; Wang, Wen; Holmes, Edward C; Zhang, Yong-Zhen

2014-08-30

The recent discovery of numerous hantaviruses in insectivores has provided a new view of hantavirus biodiversity and evolution. To determine the presence and genetic diversity of Imjin virus (MJNV) and Thottapalayam virus (TPMV) in insectivores in Zhejiang Province, China, we captured and performed virus screening of 32 Ussuri white-toothed shrews (Crocidura lasiura) and 105 Asian house shrews (Suncus murinus) in different coastal regions. Hantavirus genome (S, M, and L segments) sequences were successfully recovered from one Ussuri white-toothed shrew and seven Asian house shrews. Phylogenetic analysis revealed that the virus carried by the Ussuri white-toothed shrew was most closely related to MJNV, but with >15% nucleotide sequence difference, suggesting that it represents a new subtype. The hantaviruses carried by Asian house shrews were closely related to the TPMV variants found in the same geographic area, but more distantly related to those sampled in India and Nepal. Additionally, the TPMV sequences obtained in this study, as well as those found previously in this area, could be divided into three lineages reflecting their geographic origins, indicative of largely allopatric evolution. Overall, our data highlights the high genetic diversity of insectivore-borne hantaviruses in China, suggesting that more may be discovered in the future. Copyright © 2014 Elsevier B.V. All rights reserved.

Discovery of Novel Alphacoronaviruses in European Rodents and Shrews

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Theocharis Tsoleridis

2016-03-01

Full Text Available Eight hundred and thirteen European rodents and shrews encompassing seven different species were screened for alphacoronaviruses using PCR detection. Novel alphacoronaviruses were detected in the species Rattus norvegicus, Microtus agrestis, Sorex araneus and Myodes glareolus. These, together with the recently described Lucheng virus found in China, form a distinct rodent/shrew-specific clade within the coronavirus phylogeny. Across a highly conserved region of the viral polymerase gene, the new members of this clade were up to 22% dissimilar at the nucleotide level to the previously described Lucheng virus. As such they might represent distinct species of alphacoronaviruses. These data greatly extend our knowledge of wildlife reservoirs of alphacoronaviruses.

Incidence of dental lesions in musk shrews (Suncus murinus) and their association with sex, age, body weight and diet.

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Dudley, Emily S; Grunden, Beverly K; Crocker, Conan; Boivin, Gregory P

2013-10-22

Both wild and laboratory strains of the musk shrew (Suncus murinus) have a high incidence of periodontitis. The authors completed necropsy examinations in 51 shrews to identify dental lesions including tooth loss, mobility and fractures. Dental lesions were identified in significantly more females than males, and older animals were more likely to have lesions present. Shrews with one or more dental lesions weighed significantly less than those without lesions present. Dietary supplementation with mealworms did not significantly affect the incidence of dental lesions or the body weight of male or female shrews. The authors recommend routine body weight measurement as a simple, noninvasive method of detecting shrews with an increased likelihood of having dental lesions.

Depletion of endogenous germ cells in tree shrews in preparation for spermatogonial transplantation.

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Liu, Tingting; Guo, Ying; Yan, Lanzhen; Sun, Bin; Zheng, Ping; Zhao, Xudong

2017-09-01

To achieve successful spermatogonial transplantation, endogenous germ cells must be depleted in recipient animals to allow donor germ cells to colonize efficiently. Busulfan is commonly used for the depletion of endogenous germ cells in recipient males. However, the optimal dose of busulfan is species-specific, and the optimal dose in tree shrews is yet to be determined. The current study aimed to determine the optimal dose of busulfan for effective suppression of endogenous spermatogenesis in tree shrews. Different doses (15, 20, 25, 30, 35, 40 and 45 mg/kg) of busulfan were injected into tree shrews intraperitoneally. Survival rates of the different treatment groups were calculated at 2 weeks and body weights were measured at 4, 6, 8, 10 and 28 weeks post-busulfan treatment. The testes were also removed and weighed at 4, 6, 8, 10 and 28 weeks post-treatment, and the cross and longitude diameters of the testes and diameters of the seminiferous tubules were measured and histologically evaluated. It was observed that there were no significant differences in the survival rates between the 15-35 mg/kg treatment groups and the control group (P>0.05), while the survival rate of the 40 mg/kg treatment group significantly decreased relative to the control group (Pendogenous germ cells in tree shrews. This dose led to maximum suppression of endogenous spermatogenesis while maintaining an acceptable survival rate of >50% of the lethal dose of busulfan for tree shrews.

Two new species of shrews (Soricidae) from the western highlands of Guatemala

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Woodman, Neal

2010-01-01

The broad-clawed shrews (Soricomorpha: Soricidae: Cryptotis) encompass a clade of 5 species—Cryptotis alticolus (Merriam), C. goldmani (Merriam), C. goodwini Jackson, C. griseoventris Jackson, and C. peregrinus (Merriam)—that is known collectively as the Cryptotis goldmani group and is characterized by broadened forefeet, elongated and broadened fore claws, and broadened humeri. These shrews are distributed in highland regions from central Mexico to Honduras. Two broad-clawed shrews, C. goodwini and C. griseoventris, occur in southern Mexico and Guatemala and are presumed sister species whose primary distinguishing feature is the larger size of C. goodwini. In an investigation of variation within and between these 2 species, I studied characteristics of the postcranial skeleton. Statistical analyses of a variety of character suites indicate that the forelimb morphology in this group exhibits less intraspecific variation and greater interspecific variation than cranio-mandibular morphology, although most skull characters support groupings based on forelimb characters. Together, these characters define 4 distinct groups among the specimens examined. C. griseoventris is restricted to the northern highlands of Chiapas, Mexico, and C. goodwini occurs in the southern highlands of Chiapas and Guatemala. Herein, I describe 2 new species of broad-clawed shrews from the Sierra de los Cuchumatanes, Guatemala.

Trend of Complete Hydatidiform Mole

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K Thapa

2010-03-01

Full Text Available INTRODUCTION: Complete Hydatidiform mole is one of the most frequent abnormal pregnancies. This review studies the trend of complete mole in Paropakar Maternity and Women's hospital and clinical ability to detect it. METHODS: This is a retrospective study of 504 cases of complete hydatidiform mole recorded at Paropakar maternity and women's hospital, Kathmandu, during 2058-2065 B.S. Medical records were reviewed and incidence, clinical presentation and method of diagnosis were studied. RESULTS: During the study period, there were 13,9117 births and 504 complete moles, 12 partial moles, 48 persistent gestational tumours, six choriocarcinoma and four invasive moles recorded in the hospital. The incidence of complete mole was one per 276 births. It was prevalent among women younger than 29 years (80% and among the primigravidae (36.7%. More than 90% women presented in the first half of their pregnancy and vaginal bleeding was the main complaint (68.3%. Suction evacuation, dilation and evacuation followed by sharp curettage and abdominal hysterectomy were performed in 80.6%, 17.6% and 1.2% of the women respectively. Persistent mole and choriocarcinoma developed in 9.5% and 0.4% respectively. CONCLUSIONS: Complete mole has the highest incidence. It affects mostly younger women and presents with vaginal bleeding most of the time, usually in the first half of their pregnancy. Keywords: complete hydatidiform mole, gestational trophoblastic disease, persistent gestational tumours.

Captures of Crawford's gray shrews (Notiosorex crawfordi) along the Rio Grande in central New Mexico

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Alice Chung-MacCoubrey; Heather L. Bateman; Deborah M. Finch

2009-01-01

We captured >2000 Crawford's gray shrews (Notiosorex crawfordi) in a riparian forest mainly consisting of cottonwoods (Populus deltoides) along the Rio Grande in central New Mexico. Little has been published about abundance and habitat of Crawford's gray shrew throughout its distributional range. During 7 summers, we...

Muscle Senescence in Short-Lived Wild Mammals, the Soricine Shrews Blarina brevicauda and Sorex palustris

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HINDLE, ALLYSON G.; LAWLER, JOHN M.; CAMPBELL, KEVIN L.; HORNING, MARKUS

2015-01-01

Red-toothed (soricine) shrews are consummate predators exhibiting the highest energy turnovers and shortest life spans (ca. 18 months) of any mammal, yet virtually nothing is known regarding their physiological aging. We assessed the emerging pattern of skeletal muscle senescence (contractile/connective tissue components) in sympatric species, the semi-aquatic water shrew (WS), Sorex palustris, and the terrestrial short-tailed shrew (STS), Blarina brevicauda, to determine if muscle aging occurs in wild, short-lived mammals (H0: shrews do not survive to an age where senescence occurs), and if so, whether these alterations are species-specific. Gracilis muscles were collected from first-year (n = 17) and second-year (n = 17) field-caught shrews. Consistent with typical mammalian aging, collagen content (% area) increased with age in both species (S. palustris: ~50%; B. brevicauda: ~60%). Muscle was dominated by stiffer Type I collagen, and the ratio of collagen Type I:Type III more than doubled with age. The area ratio of muscle:collagen decreased with age in both species, but was considerably lower in adult STS, suggesting species-specificity of senescence. Extracellular space was age-elevated in B. brevicauda, but was preserved in S. palustris (~50 vs. 10% elevation). Though juvenile interspecific comparisons revealed no significance, adult WS myocytes had 68% larger cross-sectional area and occurred at 28% lower fibers/area than those of adult STS. We demonstrate that age-related muscle senescence does occur in wild-caught, short-lived mammals, and we therefore reject this classic aging theory tenet. Our findings moreover illustrate that differential age adjustments in contractile/connective tissue components of muscle occur in the two species of wild-caught shrews. PMID:19296507

Varied behavioral responses induced by morphine in the tree shrew: a possible model for human opiate addiction

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Fang eShen

2014-09-01

Full Text Available Tree shrews represent a suitable animal model to study the pathogenesis of human diseases as they are phylogenetically close to primates and have a well-developed central nervous system that possesses many homologies with primates. Therefore, in our study, we investigated whether tree shrews can be used to explore the addictive behaviors induced by morphine. Firstly, to investigate the psychoactive effect of morphine on tree shrews’ behavior, the number of jumping and shuttling, which represent the vertical and horizontal locomotor activity respectively, was examined following the injection of different dosage of morphine. Our results showed intramuscular (IM injection of morphine (5 or 10 mg/kg significantly increased the locomotor activity of tree shrews 30-60 min post-injection. Then, using the conditioned place preference/aversion (CPP/CPA paradigm, we found morphine-conditioned tree shrews exhibited place preference in the morphine-paired chamber on the test day. In addition, naloxone-precipitated withdrawal induced place aversion in the chronic morphine-dependent tree shrews. We evaluated the craving for morphine drinking by assessing the break point that reflects the maximum effort animals will expend to get the drug. Our data showed the break point was significantly increased when compared to the baseline on the 1st, 7th and 14th day after the abstinence. Moreover, in the intravenous morphine self-administration experiment, tree shrews conditioned with morphine responded on the active lever significantly more frequently than on the inactive lever after training. These results suggest that tree shrew may be a potential candidate for study the addictive behaviors and the underling neurological mechanisms.

Improved Starch Digestion of Sucrase-deficient Shrews Treated With Oral Glucoamylase Enzyme Supplements.

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Nichols, Buford L; Avery, Stephen E; Quezada-Calvillo, Roberto; Kilani, Shadi B; Lin, Amy Hui-Mei; Burrin, Douglas G; Hodges, Benjamin E; Chacko, Shaji K; Opekun, Antone R; Hindawy, Marwa El; Hamaker, Bruce R; Oda, Sen-Ichi

2017-08-01

Although named because of its sucrose hydrolytic activity, this mucosal enzyme plays a leading role in starch digestion because of its maltase and glucoamylase activities. Sucrase-deficient mutant shrews, Suncus murinus, were used as a model to investigate starch digestion in patients with congenital sucrase-isomaltase deficiency.Starch digestion is much more complex than sucrose digestion. Six enzyme activities, 2 α-amylases (Amy), and 4 mucosal α-glucosidases (maltases), including maltase-glucoamylase (Mgam) and sucrase-isomaltase (Si) subunit activities, are needed to digest starch to absorbable free glucose. Amy breaks down insoluble starch to soluble dextrins; mucosal Mgam and Si can either directly digest starch to glucose or convert the post-α-amylolytic dextrins to glucose. Starch digestion is reduced because of sucrase deficiency and oral glucoamylase enzyme supplement can correct the starch maldigestion. The aim of the present study was to measure glucogenesis in suc/suc shrews after feeding of starch and improvement of glucogenesis by oral glucoamylase supplements. Sucrase mutant (suc/suc) and heterozygous (+/suc) shrews were fed with C-enriched starch diets. Glucogenesis derived from starch was measured as blood C-glucose enrichment and oral recombinant C-terminal Mgam glucoamylase (M20) was supplemented to improve starch digestion. After feedings, suc/suc and +/suc shrews had different starch digestions as shown by blood glucose enrichment and the suc/suc had lower total glucose concentrations. Oral supplements of glucoamylase increased suc/suc total blood glucose and quantitative starch digestion to glucose. Sucrase deficiency, in this model of congenital sucrase-isomaltase deficiency, reduces blood glucose response to starch feeding. Supplementing the diet with oral recombinant glucoamylase significantly improved starch digestion in the sucrase-deficient shrew.

Estimation of body surface area in the musk shrew ( Suncus murinus): a small animal for testing chemotherapy-induced emesis.

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Eiseman, Julie L; Sciullo, Michael; Wang, Hong; Beumer, Jan H; Horn, Charles C

2017-10-01

Several cancer chemotherapies cause nausea and vomiting, which can be dose-limiting. Musk shrews are used as preclinical models for chemotherapy-induced emesis and for antiemetic effectiveness. Unlike rats and mice, shrews possess a vomiting reflex and demonstrate an emetic profile similar to humans, including acute and delayed phases. As with most animals, dosing of shrews is based on body weight, while translation of such doses to clinically equivalent exposure requires doses based on body surface area. In the current study body surface area in musk shrews was directly assessed to determine the Meeh constant (K m ) conversion factor (female = 9.97, male = 9.10), allowing estimation of body surface area based on body weight. These parameters can be used to determine dosing strategies for shrew studies that model human drug exposures, particularly for investigating the emetic liability of cancer chemotherapeutic agents.

The Fetal Membranes of the Otter Shrews and a Synapomorphy for Afrotheria

DEFF Research Database (Denmark)

Carter, Anthony M.; Blankenship, T.N.; Enders, A.C.

2006-01-01

The otter shrews of mainland Africa are the closest relatives of the Madagascar tenrecs. We sought for similarities in placentation between the two groups and, in a wider context, with other mammals of the Afrotheria clade. Specimens of the Nimba otter shrew (Micropotamogale lamottei) were obtain...... by two pairs of septal folds. A similar arrangement has been described for representatives of each of the remaining five orders within Afrotheria. This is significant because previous anatomical studies have failed to establish a single synapomorphy in support of Afrotheria....

Muscle senescence in short-lived wild mammals, the soricine shrews Blarina brevicauda and Sorex palustris.

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Hindle, Allyson G; Lawler, John M; Campbell, Kevin L; Horning, Markus

2009-06-01

Red-toothed (soricine) shrews are consummate predators exhibiting the highest energy turnovers and shortest life spans (ca. 18 months) of any mammal, yet virtually nothing is known regarding their physiological aging. We assessed the emerging pattern of skeletal muscle senescence (contractile/connective tissue components) in sympatric species, the semi-aquatic water shrew (WS), Sorex palustris, and the terrestrial short-tailed shrew (STS), Blarina brevicauda, to determine if muscle aging occurs in wild, short-lived mammals (H(0): shrews do not survive to an age where senescence occurs), and if so, whether these alterations are species-specific. Gracilis muscles were collected from first-year (n=17) and second-year (n=17) field-caught shrews. Consistent with typical mammalian aging, collagen content (% area) increased with age in both species (S. palustris: approximately 50%; B. brevicauda: approximately 60%). Muscle was dominated by stiffer Type I collagen, and the ratio of collagen Type I:Type III more than doubled with age. The area ratio of muscle:collagen decreased with age in both species, but was considerably lower in adult STS, suggesting species-specificity of senescence. Extracellular space was age-elevated in B. brevicauda, but was preserved in S. palustris ( approximately 50 vs. 10% elevation). Though juvenile interspecific comparisons revealed no significance, adult WS myocytes had 68% larger cross-sectional area and occurred at 28% lower fibers/area than those of adult STS. We demonstrate that age-related muscle senescence does occur in wild-caught, short-lived mammals, and we therefore reject this classic aging theory tenet. Our findings moreover illustrate that differential age adjustments in contractile/connective tissue components of muscle occur in the two species of wild-caught shrews. (c) 2009 Wiley-Liss, Inc.

Telemetric Study of Sleep Architecture and Sleep Homeostasis in the Day-Active Tree Shrew Tupaia belangeri

NARCIS (Netherlands)

Coolen, Alex; Hoffmann, Kerstin; Barf, R. Paulien; Fuchs, Eberhard; Meerlo, Peter

2012-01-01

Study Objectives: In this study the authors characterized sleep architecture and sleep homeostasis in the tree shrew, Tupaia belangeri, a small, omnivorous, day-active mammal that is closely related to primates. Design: Adult tree shrews were individually housed under a 12-hr light/12-hr dark cycle

Isolation and identification of symbiotic bacteria from the skin, mouth, and rectum of wild and captive tree shrews.

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Li, Gui; Lai, Ren; Duan, Gang; Lyu, Long-Bao; Zhang, Zhi-Ye; Liu, Huang; Xiang, Xun

2014-11-18

Endosymbionts influence many aspects of their hosts' health conditions, including physiology, development, immunity, metabolism, etc. Tree shrews (Tupaia belangeri chinensis) have attracted increasing attention in modeling human diseases and therapeutic responses due to their close relationship with primates. To clarify the situation of symbiotic bacteria from their body surface, oral cavity, and anus, 12 wild and 12 the third generation of captive tree shrews were examined. Based on morphological and cultural characteristics, physiological and biochemical tests, as well as the 16S rDNA full sequence analysis, 12 bacteria strains were isolated and identified from the wild tree shrews: body surface: Bacillus subtilis (detection rate 42%), Pseudomonas aeruginosa (25%), Staphlococcus aureus (33%), S. Epidermidis (75%), Micrococcus luteus (25%), Kurthia gibsonii (17%); oral cavity: Neisseria mucosa (58%), Streptococcus pneumonia (17%); anus: Enterococcus faecalis (17%), Lactococus lactis (33%), Escherichia coli (92%), Salmonella typhosa (17%); whereas, four were indentified from the third generation captive tree shrews: body surface: S. epidermidis (75%); oral cavity: N.mucosa (67%); anus: L. lactis (33%), E. coli (100%). These results indicate that S. epidermidis, N. mucosa, L. lactis and E. coli were major bacteria in tree shrews, whereas, S. aureus, M. luteus, K. gibsonii, E. faecalis and S. typhosa were species-specific flora. This study facilitates the future use of tree shrews as a standard experimental animal and improves our understanding of the relationship between endosymbionts and their hosts.

Mole gun injury.

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Pistré, V; Rezzouk, J

2013-09-01

A mole gun is a weapon, which is used to trap and kill moles. This report provides an overview of the state of knowledge of mole gun injuries, comparable to blast injuries caused by fireworks, explosive or gunshot. Over a 2-year period, the authors reported their experience with ten hand injuries caused by mole gun. Radial side of the hand was often concerned, particularly the thumb. The authors explain their choices in the management of such lesions. Surgery was performed primarily and a large debridement currently seemed to offer the best outcome for the patient. Blast, crush, burns and lacerations may explain the higher rate of amputation to the digits. A long period of physiotherapy, specifically of the hand, was needed before the patient could return to work. This ballistic hand trauma encountered by surgeons requires knowledge and understanding of these injuries. It should be in accordance with firearms law because of severe injuries encountered and possible lethal wounds. Copyright © 2013 Elsevier Masson SAS. All rights reserved.

Resting-associated vocalization emitted by captive Asian house shrews (Suncus murinus: acoustic structure and variability in an unusual mammalian vocalization.

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Irena Schneiderová

Full Text Available Shrews have rich vocal repertoires that include vocalizations within the human audible frequency range and ultrasonic vocalizations. Here, we recorded and analyzed in detail the acoustic structure of a vocalization with unclear functional significance that was spontaneously produced by 15 adult, captive Asian house shrews (Suncus murinus while they were lying motionless and resting in their nests. This vocalization was usually emitted repeatedly in a long series with regular intervals. It showed some structural variability; however, the shrews most frequently emitted a tonal, low-frequency vocalization with minimal frequency modulation and a low, non-vocal click that was clearly noticeable at its beginning. There was no effect of sex, but the acoustic structure of the analyzed vocalizations differed significantly between individual shrews. The encoded individuality was low, but it cannot be excluded that this individuality would allow discrimination of family members, i.e., a male and female with their young, collectively resting in a common nest. The question remains whether the Asian house shrews indeed perceive the presence of their mates, parents or young resting in a common nest via the resting-associated vocalization and whether they use it to discriminate among their family members. Additional studies are needed to explain the possible functional significance of resting-associated vocalizations emitted by captive Asian house shrews. Our study highlights that the acoustic communication of shrews is a relatively understudied topic, particularly considering that they are highly vocal mammals.

Molecular evidence and high genetic diversity of shrew-borne Seewis virus in Slovenia.

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Resman, Katarina; Korva, Miša; Fajs, Luka; Zidarič, Tanja; Trilar, Tomi; Zupanc, Tatjana Avšič

2013-10-01

Seewis virus, the shrew-borne hantavirus from Sorex araneus, has been molecularly detected in reservoir hosts in many different central European countries and Russia. Slovenia is a known endemic country for rodent-borne hantaviruses, therefore the aim of the study was to investigate the presence of shrew-borne hantaviruses in insectivores. Viral L, S and M segment have been recovered only from tissue samples of 7 S. araneus, despite several shrew species were tested. Phylogenetic analysis showed high genetic diversity of SWSV in Slovenia, ranging from 3 to 19.4% for different viral segments. The most divergent were M segment sequences, with 19.4% nucleotide divergence among Slovenian strains. Above that, different SWSV strains from Slovenia do not group into separate geographic clusters. While three separate genetic clades were determined, two of them were simultaneously present in one location at the same time. Copyright © 2013 Elsevier B.V. All rights reserved.

Multilocus phylogeography and systematic revision of North American water shrews (genus: Sorex)

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Hope, Andrew G.; Panter, Nicholas; Cook, Joseph A.; Talbot, Sandra L.; Nagorsen, David W.

2014-01-01

North American water shrews, which have traditionally included Sorex alaskanus, S. bendirii, and S. palustris, are widely distributed through Nearctic boreal forests and adapted for life in semiaquatic environments. Molecular mitochondrial signatures for these species have recorded an evolutionary history with variable levels of regional divergence, suggesting a strong role of Quaternary environmental change in speciation processes. We expanded molecular analyses, including more-comprehensive rangewide sampling of specimens representing North American water shrew taxa, except S. alaskanus, and sequencing of 4 independent loci from the nuclear and mitochondrial genomes. We investigated relative divergence of insular populations along the North Pacific Coast, and newly recognized diversity from southwestern montane locations, potentially representing refugial isolates. Congruent independent genealogies, lack of definitive evidence for contemporary gene flow, and high support from coalescent species trees indicated differentiation of 4 major geographic lineages over multiple glacial cycles of the late Quaternary, similar to a growing number of boreal taxa. Limited divergence of insular populations suggested colonization following the last glacial. Characterization of southwestern montane diversity will require further sampling but divergence over multiple loci is indicative of a relictual sky-island fauna. We have reviewed and revised North American water shrew taxonomy including the recognition of 3 species within what was previously known as S. palustris. The possibility of gene flow between most distantly related North American water shrew lineages coupled with unresolved early diversification of this group and other sibling species reflects a complex but potentially productive system for investigating speciation processes.

Microgeographical distribution of shrews (Mammalia, Soricidae) in the Congo River basin (Kisangani, D.R. Congo)

DEFF Research Database (Denmark)

Gambalemoke, Mbalitini; Mukinzi, Itoka; Amundala, Drazo

2008-01-01

Research on the biodiversity of shrews was conducted in eight forest blocks at eight sampling localities: Djabir, Maiko, Masako, Yoko, Yelenge, Baliko, Bomane-1 and Bomane-2. We used pitfall traps combined with Sherman LFA traps placed on transects. We collected 724 shrews from primary forests, s...

The relative host status of rock elephant shrews Elephantulus ...

African Journals Online (AJOL)

1991-10-18

Oct 18, 1991 ... rocky terrain, occur in South Africa (Smithers 1983) and the distribution of ... elephant shrews on northern and on southern slopes on the farm 'Preezfon- .... this has caused paralysis in Angora goat kids (Fourie et al. 1988a).

Molecular cloning and characterization of the full-length cDNA encoding the tree shrew (tupaia belangeri) CD28

Science.gov (United States)

Huang, Xiaoyan; Yan, Yan; Wang, Sha; Wang, Qinying; Shi, Jian; Shao, Zhanshe; Dai, Jiejie

2017-11-01

CD28 is one of the most important co-stimulatory molecules expressed by naive and primed T cells. The tree shrews (Tupaia belangeri), as an ideal animal model for analyzing mechanism of human diseases receiving extensive attentions, demands essential research tools, in particular in the study of cellular markers and monoclonal antibodies for immunological studies. However, little is known about tree shrew CD28 (tsCD28) until now. In this study, a 663 bp of the full-length CD28 cDNA, encoding a polypeptide of 220 amino acids was cloned from tree shrew spleen lymphocytes. The nucleotide sequence of the tsCD28 showed 85%, 76%, and 75% similarities with human, rat, and mouse, respectively, which showed the affinity relationship between tree shrew and human is much closer than between human and rodents. The open reading frame (ORF) sequence of tsCD28 gene was predicted to be in correspondence with the signal sequence, immunoglobulin variable-like (IgV) domain, transmembrane domain and cytoplasmic tail, respectively.We also analyzed its molecular characteristics with other mammals by using biology software such as Clustal W 2.0 and so forth. Our results showed that tsCD28 contained many features conserved in CD28 genes from other mammals, including conserved signal peptide and glycosylation sites, and several residues responsible for binding to the CD28R, and the tsCD28 amino acid sequence were found a close genetic relationship with human and monkey. The crystal structure and surface charge revealed most regions of tree shrew CD28 molecule surface charges are similar as human. However, compared with human CD28 (hCD28) regions, in some areas, the surface positive charge of tsCD28 was less than hCD28, which may affect antibody binding. The present study is the first report of cloning and characterization of CD28 in tree shrew. This study provides a theoretical basis for the further study the structure and function of tree shrew CD28 and utilize tree shrew as an effective

Isolation and characterization of a novel arenavirus harbored by Rodents and Shrews in Zhejiang province, China

Energy Technology Data Exchange (ETDEWEB)

Li, Kun [State Key Laboratory for Infectious Disease Prevention and Control, Department of Zoonoses, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping, Beijing (China); Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Hangzhou (China); Lin, Xian-Dan [Wenzhou Center for Disease Control and Prevention, Wenzhou, Zhejiang Province (China); Wang, Wen [State Key Laboratory for Infectious Disease Prevention and Control, Department of Zoonoses, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping, Beijing (China); Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Hangzhou (China); Shi, Mang [State Key Laboratory for Infectious Disease Prevention and Control, Department of Zoonoses, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping, Beijing (China); Wencheng Center for Disease Control and Prevention, Wenzhou, Zhejiang Province (China); Guo, Wen-Ping [State Key Laboratory for Infectious Disease Prevention and Control, Department of Zoonoses, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping, Beijing (China); Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Hangzhou (China); Zhang, Xiao-He [Wenzhou Center for Disease Control and Prevention, Wenzhou, Zhejiang Province (China); Xing, Jian-Guang [Wencheng Center for Disease Control and Prevention, Wenzhou, Zhejiang Province (China); and others

2015-02-15

To determine the biodiversity of arenaviruses in China, we captured and screened rodents and shrews in Wenzhou city, Zhejiang province, a locality where hemorrhagic fever diseases are endemic in humans. Accordingly, arenaviruses were detected in 42 of 351 rodents from eight species, and in 12 of 272 Asian house shrews (Suncus murinus), by RT-PCR targeting the L segment. From these, a single arenavirus was successfully isolated in cell culture. The virion particles exhibited a typical arenavirus morphology under transmission electron microscopy. Comparison of the S and L segment sequences revealed high levels of nucleotide (>32.2% and >39.6%) and amino acid (>28.8% and >43.8%) sequence differences from known arenaviruses, suggesting that it represents a novel arenavirus, which we designated Wenzhou virus (WENV). Phylogenetic analysis revealed that all WENV strains harbored by both rodents and Asian house shrews formed a distinct lineage most closely related to Old World arenaviruses. - Highlights: • A novel arenavirus (Wenzhou virus) was identified in Zhejiang province, China. • The virus is highly circulating in five species of rats and one species of shrews • More efforts are needed to infer whether it is pathogenic to humans or not.

Persistence and diversification of the Holarctic shrew, Sorex tundrensis (Family Soricidae), in response to climate change

Science.gov (United States)

Hope, Andrew G.; Waltari, Eric; Fedorov, Vadim B.; Goropashnaya, Anna V.; Talbot, Sandra; Cook, Joseph A.

2011-01-01

Environmental processes govern demography, species movements, community turnover and diversification and yet in many respects these dynamics are still poorly understood at high latitudes. We investigate the combined effects of climate change and geography through time for a widespread Holarctic shrew, Sorex tundrensis. We include a comprehensive suite of closely related outgroup taxa and three independent loci to explore phylogeographic structure and historical demography. We then explore the implications of these findings for other members of boreal communities. The tundra shrew and its sister species, the Tien Shan shrew (Sorex asper), exhibit strong geographic population structure across Siberia and into Beringia illustrating local centres of endemism that correspond to Late Pleistocene refugia. Ecological niche predictions for both current and historical distributions indicate a model of persistence through time despite dramatic climate change. Species tree estimation under a coalescent process suggests that isolation between populations has been maintained across timeframes deeper than the periodicity of Pleistocene glacial cycling. That some species such as the tundra shrew have a history of persistence largely independent of changing climate, whereas other boreal species shifted their ranges in response to climate change, highlights the dynamic processes of community assembly at high latitudes.

Persistence and diversification of the Holarctic shrew, Sorex tundrensis (Family Soricidae), in response to climate change

Science.gov (United States)

Hope, Andrew G.; Waltari, Eric; Fedorov, V.B.; Goropashnaya, A.V.; Talbot, Sandra; Cook, Joseph A.

2014-01-01

Environmental processes govern demography, species movements, community turnover and diversification and yet in many respects these dynamics are still poorly understood at high latitudes. We investigate the combined effects of climate change and geography through time for a widespread Holarctic shrew, Sorex tundrensis. We include a comprehensive suite of closely related outgroup taxa and three independent loci to explore phylogeographic structure and historical demography. We then explore the implications of these findings for other members of boreal communities. The tundra shrew and its sister species, the Tien Shan shrew (Sorex asper), exhibit strong geographic population structure across Siberia and into Beringia illustrating local centres of endemism that correspond to Late Pleistocene refugia. Ecological niche predictions for both current and historical distributions indicate a model of persistence through time despite dramatic climate change. Species tree estimation under a coalescent process suggests that isolation between populations has been maintained across timeframes deeper than the periodicity of Pleistocene glacial cycling. That some species such as the tundra shrew have a history of persistence largely independent of changing climate, whereas other boreal species shifted their ranges in response to climate change, highlights the dynamic processes of community assembly at high latitudes.

Prevalence and diversity of gastrointestinal helminths in free-ranging Asian house shrew (Suncus murinus) in Bangladesh.

Science.gov (United States)

Rahman, Mizanur; Islam, Shariful; Masuduzzaman, Md; Alam, Mahabub; Chawdhury, Mohammad Nizam Uddin; Ferdous, Jinnat; Islam, Md Nurul; Hassan, Mohammad Mahmudul; Hossain, Mohammad Alamgir; Islam, Ariful

2018-04-01

Asian house shrew ( Suncus murinus ), a widely distributed small mammal in the South Asian region, can carry helminths of zoonotic importance. The aim of the study was to know the prevalence and diversity of gastrointestinal (GI) helminths in free-ranging Asian house shrew ( S. murinus ) in Bangladesh. A total of 86 Asian house shrews were captured from forest areas and other habitats of Bangladesh in 2015. Gross examination of the whole GI tract was performed for gross helminth detection, and coproscopy was done for identification of specific eggs or larvae. The overall prevalence of GI helminth was 77.9% (67/86), with six species including nematodes (3), cestodes (2), and trematodes (1). Of the detected helminths, the dominant parasitic group was from the genus Hymenolepis spp.(59%), followed by Strongyloides spp.(17%), Capillaria spp. (10%), Physaloptera spp. (3%), and Echinostoma spp.(3%). The finding shows that the presence of potential zoonotic parasites (Hymenolepis spp. and Capillaria spp.) in Asian house shrew is ubiquitous in all types of habitat (forest land, cropland and dwelling) in Bangladesh. Therefore, further investigation is crucial to examine their role in the transmission of human helminthiasis.

Isolation and characterization of a novel arenavirus harbored by Rodents and Shrews in Zhejiang province, China

International Nuclear Information System (INIS)

Li, Kun; Lin, Xian-Dan; Wang, Wen; Shi, Mang; Guo, Wen-Ping; Zhang, Xiao-He; Xing, Jian-Guang

2015-01-01

To determine the biodiversity of arenaviruses in China, we captured and screened rodents and shrews in Wenzhou city, Zhejiang province, a locality where hemorrhagic fever diseases are endemic in humans. Accordingly, arenaviruses were detected in 42 of 351 rodents from eight species, and in 12 of 272 Asian house shrews (Suncus murinus), by RT-PCR targeting the L segment. From these, a single arenavirus was successfully isolated in cell culture. The virion particles exhibited a typical arenavirus morphology under transmission electron microscopy. Comparison of the S and L segment sequences revealed high levels of nucleotide (>32.2% and >39.6%) and amino acid (>28.8% and >43.8%) sequence differences from known arenaviruses, suggesting that it represents a novel arenavirus, which we designated Wenzhou virus (WENV). Phylogenetic analysis revealed that all WENV strains harbored by both rodents and Asian house shrews formed a distinct lineage most closely related to Old World arenaviruses. - Highlights: • A novel arenavirus (Wenzhou virus) was identified in Zhejiang province, China. • The virus is highly circulating in five species of rats and one species of shrews • More efforts are needed to infer whether it is pathogenic to humans or not

Development of a tree shrew metabolic syndrome model and use of umbilical cord mesenchymal stem cell transplantation for treatment.

Science.gov (United States)

Pan, Xing-Hua; Zhu, Lu; Yao, Xiang; Liu, Ju-Fen; Li, Zi-An; Yang, Jian-Yong; Pang, Rong-Qing; Ruan, Guang-Ping

2016-12-01

The aim of this study was to establish a tree shrew metabolic syndrome model and demonstrate the utility of MSCs in treating metabolic syndrome. We used tree shrew umbilical cord mesenchymal stem cell (TS-UC-MSC) transplantation for the treatment of metabolic syndrome to demonstrate the clinical application of these stem cells and to provide a theoretical basis and reference methods for this treatment. Tree shrew metabolic syndrome model showed significant insulin resistance, high blood sugar, lipid metabolism disorders, and hypertension, consistent with the diagnostic criteria. TS-UC-MSC transplantation at 16 weeks significantly reduced blood sugar and lipid levels, improved insulin resistance and the regulation of insulin secretion, and reduced the expression levels of the pro-inflammatory cytokines IL-1 and IL-6 (P metabolic syndrome model and showed that MSC migrate in diseased organs and can attenuate metabolic syndrome severity in a tree shrew model.

Ultrasonographic findings of hydatidiform mole and missed abortion

International Nuclear Information System (INIS)

Yun, Kwang Myeong; Lee, Yeong Hwan; Chung, Hye Kyeong; Chung, Duck Soo; Kim, Ok Dong

1990-01-01

To establish the sonographic characteristics of the hydatidiform mole and the missed abortion with placental degeneration, we have retrospectively analyzed 12 cases of complete mole, 10 cases of partial mole, and 10 cases of missed abortion with placental hydropic degeneration, collected at Taegu Catholic General Hospital, from January 1986 to December 1989. The results were as follows : 1. Of 12 cases of complete mole, all demonstrated diffuse intrauterine vesicular pattern of internal echo without a gestational sac. Two cases were recurred after D and E. 2. The partial mole was characterized by focal (70%) or diffuse (20%) distribution of hydatidiform placental change and a gestational sac (100%) with or without a macerated fetus. But the striking hydatidiform placental change was not present in one cases of partial mole. 3. The uterus was larger for dates in 9 cases (90%) of complete mole, but smaller for dates in 7 cases (70%) of partial mole. 4. The missed abortion with placental hydropic degeneration was indistinguished from a partial mole due to their similar sonographic appearance : focal or diffuse cystic change of a placenta, a distorted gestational sac with or without a fetus, and a smaller uterus for dates. On conclusion, the complete mole could be easily distinguished from a partial mole or a missed abortion by sonography : a gestational sac or an area of noncystic placenta was not identified in a complete mole. The partial mole was indistinguished from a missed abortion, but if there is the suspicion of trophoblastic proliferation, such as a convex placental surface or a larger uterus for dates, then the diagnosis is probably a partial mole rather than a missed abortion

Dietary competition between the alien Asian Musk Shrew (Suncus murinus) and a re-introduced population of Telfair's Skink (Leiolopisma telfairii).

Science.gov (United States)

Brown, D S; Burger, R; Cole, N; Vencatasamy, D; Clare, E L; Montazam, A; Symondson, W O C

2014-08-01

Re-introduction of rare species to parts of their historical range is becoming increasingly important as a conservation strategy. Telfair's Skinks (Leiolopisma telfairii), once widespread on Mauritius, were until recently found only on Round Island. There it is vulnerable to stochastic events, including the introduction of alien predators that may either prey upon it or compete for food resources. Consequently, skinks have been introduced to Ile aux Aigrettes, another small Mauritian island that has been cleared of rats. However, the island has been invaded by Asian Musk Shrews (Suncus murinus), a commensal species spread by man well beyond its natural Asian range. Our aim was to use next-generation sequencing to analyse the diets of the shrews and skinks to look for niche competition. DNA was extracted from skink faeces and from the stomach contents of shrews. Application of shrew- and skink-specific primers revealed no mutual predation. The DNA was then amplified using general invertebrate primers with tags to identify individual predators, and then sequenced by 454 pyrosequencing. 119 prey MOTUs (molecular taxonomic units) were isolated, although none could be identified to species. Seeding of cladograms with known sequences allowed higher taxonomic assignments in some cases. Although most MOTUs were not shared by shrews and skinks, Pianka's niche overlap test showed significant prey overlap, suggesting potentially strong competition where food resources are limited. These results suggest that removal of the shrews from the island should remain a priority. © 2013 John Wiley & Sons Ltd.

First records of smoky shrew (sorex fumeus) in Alabama

Science.gov (United States)

Zachary Felix; Lisa J. Gatens; Yong Wang; Callie J. Schweitzer

2009-01-01

Conserving biodiversity in the southeastern United States begins with documenting the distribution and natural history of all taxa. Using pitfall traps between March 2005 and January 2006, we collected the fi rst Sorex fumeus (Smoky Shrew) specimens (44) from Alabama on the Cumberland Plateau in the northeastern portion of the state....

Can they dig it? Functional morphology and semifossoriality among small-eared shrews, genus Cryptotis (Mammalia, Soricidae)

Science.gov (United States)

Woodman, Neal; Gaffney, Sarah A.

2014-01-01

Small-eared shrews (Mammalia: Soricidae: Cryptotis), exhibit modifications of the forelimb skeleton that have been interpreted as adaptations for semifossoriality. Most species inhabit remote regions, however, and their locomotory and foraging behaviors remain mostly speculative. To better understand the morphological modifications in the absence of direct observations, we quantified variation in these species by measuring 151 individuals representing 18 species and populations of Cryptotis and two species of moles (Talpidae) for comparison. From our measurements, we calculated 22 indices, most of which have been used previously to characterize substrate use among rodents and other taxa. We analyzed the indices using 1) average percentile ranks, 2) principal components analysis, and 3) cluster analysis. From these analyses, we determined that three basic modes of substrate adaptation are present within Cryptotis: 1) a primarily terrestrial mode, with species that are capable of burrowing, but lack adaptations to increase digging efficiency, 2) a semifossorial mode, with species whose forelimbs bones show strong muscle attachment areas and increased mechanical advantage, and 3) an intermediate mode. In addition to identifying new morphological characters and contributing to our understanding of the functional morphology of soricids, these analyses provide additional insight into the ecology of the species of interest.

Prevalence and diversity of gastrointestinal helminths in free-ranging Asian house shrew (Suncus murinus in Bangladesh

Directory of Open Access Journals (Sweden)

Mizanur Rahman

2018-04-01

Full Text Available Background and Aim: Asian house shrew (Suncus murinus, a widely distributed small mammal in the South Asian region, can carry helminths of zoonotic importance. The aim of the study was to know the prevalence and diversity of gastrointestinal (GI helminths in free-ranging Asian house shrew (S. murinus in Bangladesh. Materials and Methods: A total of 86 Asian house shrews were captured from forest areas and other habitats of Bangladesh in 2015. Gross examination of the whole GI tract was performed for gross helminth detection, and coproscopy was done for identification of specific eggs or larvae. Results: The overall prevalence of GI helminth was 77.9% (67/86, with six species including nematodes (3, cestodes (2, and trematodes (1. Of the detected helminths, the dominant parasitic group was from the genus Hymenolepis spp. (59%, followed by Strongyloides spp. (17%, Capillaria spp. (10%, Physaloptera spp. (3%, and Echinostoma spp. (3%. Conclusion: The finding shows that the presence of potential zoonotic parasites (Hymenolepis spp. and Capillaria spp. in Asian house shrew is ubiquitous in all types of habitat (forest land, cropland and dwelling in Bangladesh. Therefore, further investigation is crucial to examine their role in the transmission of human helminthiasis.

Prevalence and diversity of gastrointestinal helminths in free-ranging Asian house shrew (Suncus murinus) in Bangladesh

Science.gov (United States)

Rahman, Mizanur; Islam, Shariful; Masuduzzaman, Md.; Alam, Mahabub; Chawdhury, Mohammad Nizam Uddin; Ferdous, Jinnat; Islam, Md. Nurul; Hassan, Mohammad Mahmudul; Hossain, Mohammad Alamgir; Islam, Ariful

2018-01-01

Background and Aim Asian house shrew (Suncus murinus), a widely distributed small mammal in the South Asian region, can carry helminths of zoonotic importance. The aim of the study was to know the prevalence and diversity of gastrointestinal (GI) helminths in free-ranging Asian house shrew (S. murinus) in Bangladesh. Materials and Methods A total of 86 Asian house shrews were captured from forest areas and other habitats of Bangladesh in 2015. Gross examination of the whole GI tract was performed for gross helminth detection, and coproscopy was done for identification of specific eggs or larvae. Results The overall prevalence of GI helminth was 77.9% (67/86), with six species including nematodes (3), cestodes (2), and trematodes (1). Of the detected helminths, the dominant parasitic group was from the genus Hymenolepis spp.(59%), followed by Strongyloides spp.(17%), Capillaria spp. (10%), Physaloptera spp. (3%), and Echinostoma spp.(3%). Conclusion The finding shows that the presence of potential zoonotic parasites (Hymenolepis spp. and Capillaria spp.) in Asian house shrew is ubiquitous in all types of habitat (forest land, cropland and dwelling) in Bangladesh. Therefore, further investigation is crucial to examine their role in the transmission of human helminthiasis. PMID:29805224

Social structure predicts genital morphology in African mole-rats.

Directory of Open Access Journals (Sweden)

Marianne L Seney

2009-10-01

Full Text Available African mole-rats (Bathyergidae, Rodentia exhibit a wide range of social structures, from solitary to eusocial. We previously found a lack of sex differences in the external genitalia and morphology of the perineal muscles associated with the phallus in the eusocial naked mole-rat. This was quite surprising, as the external genitalia and perineal muscles are sexually dimorphic in all other mammals examined. We hypothesized that the lack of sex differences in naked mole-rats might be related to their unusual social structure.We compared the genitalia and perineal muscles in three African mole-rat species: the naked mole-rat, the solitary silvery mole-rat, and the Damaraland mole-rat, a species considered to be eusocial, but with less reproductive skew than naked mole-rats. Our findings support a relationship between social structure, mating system, and sexual differentiation. Naked mole-rats lack sex differences in genitalia and perineal morphology, silvery mole-rats exhibit sex differences, and Damaraland mole-rats are intermediate.The lack of sex differences in naked mole-rats is not an attribute of all African mole-rats, but appears to have evolved in relation to their unusual social structure and reproductive biology.

Social structure predicts genital morphology in African mole-rats.

Science.gov (United States)

Seney, Marianne L; Kelly, Diane A; Goldman, Bruce D; Sumbera, Radim; Forger, Nancy G

2009-10-15

African mole-rats (Bathyergidae, Rodentia) exhibit a wide range of social structures, from solitary to eusocial. We previously found a lack of sex differences in the external genitalia and morphology of the perineal muscles associated with the phallus in the eusocial naked mole-rat. This was quite surprising, as the external genitalia and perineal muscles are sexually dimorphic in all other mammals examined. We hypothesized that the lack of sex differences in naked mole-rats might be related to their unusual social structure. We compared the genitalia and perineal muscles in three African mole-rat species: the naked mole-rat, the solitary silvery mole-rat, and the Damaraland mole-rat, a species considered to be eusocial, but with less reproductive skew than naked mole-rats. Our findings support a relationship between social structure, mating system, and sexual differentiation. Naked mole-rats lack sex differences in genitalia and perineal morphology, silvery mole-rats exhibit sex differences, and Damaraland mole-rats are intermediate. The lack of sex differences in naked mole-rats is not an attribute of all African mole-rats, but appears to have evolved in relation to their unusual social structure and reproductive biology.

New status for two African giant forest shrews, Crocidura goliath ...

African Journals Online (AJOL)

New status for two African giant forest shrews, Crocidura goliath goliath and C. ... that C. g. nimbasilvanus is the sister taxon of C. nimbae, a species also endemic to ... Crocidura g. goliath is part of the C. olivieri group and closely related to C.

Development and characterization of 21 polymorphic microsatellite markers for the barren-ground shrew, Sorex ugyunak (Mammalia: Sorcidae), through next-generation sequencing, and cross-species amplification in the masked shrew, S. cinereus

Science.gov (United States)

Sonsthagen, Sarah A.; Sage, G. Kevin; Fowler, Megan C.; Hope, Andrew G.; Cook, J.A.; Talbot, Sandra L.

2013-01-01

We used next generation shotgun sequencing to develop 21 novel microsatellite markers for the barren-ground shrew (Sorex ugyunak), which were polymorphic among individuals from northern Alaska. The loci displayed moderate allelic diversity (averaging 6.81 alleles per locus) and heterozygosity (averaging 70 %). Two loci deviated from Hardy–Weinberg equilibrium (HWE) due to heterozygote deficiency. While the population did not deviate from HWE overall, it showed significant linkage disequilibrium suggesting this population is not in mutation-drift equilibrium. Nineteen of 21 loci were polymorphic in masked shrews (S. cinereus) from interior Alaska and exhibited linkage equilibrium and HWE overall. All loci yielded sufficient variability for use in population studies.

Yersinia spp. in Wild Rodents and Shrews in Finland.

Science.gov (United States)

Joutsen, Suvi; Laukkanen-Ninios, Riikka; Henttonen, Heikki; Niemimaa, Jukka; Voutilainen, Liina; Kallio, Eva R; Helle, Heikki; Korkeala, Hannu; Fredriksson-Ahomaa, Maria

2017-05-01

Yersinia enterocolitica and Yersinia pseudotuberculosis are important zoonotic bacteria causing human enteric yersiniosis commonly reported in Europe. All Y. pseudotuberculosis strains are considered pathogenic, while Y. enterocolitica include both pathogenic and nonpathogenic strains which can be divided into six biotypes (1A, 1B, and 2-5) and about 30 serotypes. The most common types causing yersiniosis in Europe are Y. enterocolitica bioserotypes 4/O:3 and 2/O:9. Strains belonging to biotype 1A are considered as nonpathogenic because they are missing important virulence genes like the attachment-invasion-locus (ail) gene in the chromosome and the virulence plasmid. The role of wild small mammals as a reservoir of enteropathogenic Yersinia spp. is still obscure. In this study, the presence of Yersinia spp. was examined from 1840 wild small mammals, including voles, mice, and shrews, trapped in Finland during a 7-year period. We isolated seven Yersinia species. Y. enterocolitica was the most common species, isolated from 8% of the animals; while most of these isolates represented nonpathogenic biotype 1A, human pathogenic bioserotype 2/O:9 was also isolated from a field vole. Y. pseudotuberculosis of bioserotype 1/O:2 was isolated from two shrews. The ail gene, which is typically only found in the isolates of biotypes 1B and 2-5 associated with yersiniosis, was frequently (23%) detected in the nonpathogenic isolates of biotype 1A and sporadically (6%) in Yersinia kristensenii isolates. Our results suggest that wild small mammals, especially voles, may serve as carriers for ail-positive Y. enterocolitica 1A and Y. kristensenii. We also demonstrate that voles and shrews sporadically excrete pYV-positive Y. enterocolitica 2/O:9 and Y. pseudotuberculosis 1/O:2, respectively, in their feces and, thus, can serve as a contamination source for vegetables by contaminating the soil.

The timing of the shrew: continuous melatonin treatment maintains youthful rhythmic activity in aging Crocidura russula.

Directory of Open Access Journals (Sweden)

Elodie Magnanou

2009-06-01

Full Text Available Laboratory conditions nullify the extrinsic factors that determine the wild expected lifespan and release the intrinsic or potential lifespan. Thus, wild animals reared in a laboratory often show an increased lifespan, and consequently an increased senescence phase. Senescence is associated with a broad suite of physiological changes, including a decreased responsiveness of the circadian system. The time-keeping hormone melatonin, an important chemical player in this system, is suspected to have an anti-aging role. The Greater White-toothed shrew Crocidura russula is an ideal study model to address questions related to aging and associated changes in biological functions: its lifespan is short and is substantially increased in captivity; daily and seasonal rhythms, while very marked the first year of life, are dramatically altered during the senescence process which starts during the second year. Here we report on an investigation of the effects of melatonin administration on locomotor activity of aging shrews.1 The diel fluctuations of melatonin levels in young, adult and aging shrews were quantified in the pineal gland and plasma. In both, a marked diel rhythm (low diurnal concentration; high nocturnal concentration was present in young animals but then decreased in adults, and, as a result of a loss in the nocturnal production, was absent in old animals. 2 Daily locomotor activity rhythm was monitored in pre-senescent animals that had received either a subcutaneous melatonin implant, an empty implant or no implant at all. In non-implanted and sham-implanted shrews, the rhythm was well marked in adults. A marked degradation in both period and amplitude, however, started after the age of 14-16 months. This pattern was considerably delayed in melatonin-implanted shrews who maintained the daily rhythm for significantly longer.This is the first long term study (>500 days observation of the same individuals that investigates the effects of

Geochemical mole-balance modeling with uncertain data

Science.gov (United States)

Parkhurst, David L.

1997-01-01

Geochemical mole-balance models are sets of chemical reactions that quantitatively account for changes in the chemical and isotopic composition of water along a flow path. A revised mole-balance formulation that includes an uncertainty term for each chemical and isotopic datum is derived. The revised formulation is comprised of mole-balance equations for each element or element redox state, alkalinity, electrons, solvent water, and each isotope; a charge-balance equation and an equation that relates the uncertainty terms for pH, alkalinity, and total dissolved inorganic carbon for each aqueous solution; inequality constraints on the size of the uncertainty terms; and inequality constraints on the sign of the mole transfer of reactants. The equations and inequality constraints are solved by a modification of the simplex algorithm combined with an exhaustive search for unique combinations of aqueous solutions and reactants for which the equations and inequality constraints can be solved and the uncertainty terms minimized. Additional algorithms find only the simplest mole-balance models and determine the ranges of mixing fractions for each solution and mole transfers for each reactant that are consistent with specified limits on the uncertainty terms. The revised formulation produces simpler and more robust mole-balance models and allows the significance of mixing fractions and mole transfers to be evaluated. In an example from the central Oklahoma aquifer, inclusion of up to 5% uncertainty in the chemical data can reduce the number of reactants in mole-balance models from seven or more to as few as three, these being cation exchange, dolomite dissolution, and silica precipitation. In another example from the Madison aquifer, inclusion of the charge-balance constraint requires significant increases in the mole transfers of calcite, dolomite, and organic matter, which reduce the estimated maximum carbon 14 age of the sample by about 10,000 years, from 22,700 years to

Experimental chronic hepatitis B infection of neonatal tree shrews (Tupaia belangeri chinensis: A model to study molecular causes for susceptibility and disease progression to chronic hepatitis in humans

Directory of Open Access Journals (Sweden)

Wang Qi

2012-08-01

Full Text Available Abstract Background Hepatitis B virus (HBV infection continues to be an escalating global health problem. Feasible and effective animal models for HBV infection are the prerequisite for developing novel therapies for this disease. The tree shrew (Tupaia is a small animal species evolutionary closely related to humans, and thus is permissive to certain human viral pathogens. Whether tree shrews could be chronically infected with HBV in vivo has been controversial for decades. Most published research has been reported on adult tree shrews, and only small numbers of HBV infected newborn tree shrews had been observed over short time periods. We investigated susceptibility of newborn tree shrews to experimental HBV infection as well as viral clearance over a protracted time period. Results Forty-six newborn tree shrews were inoculated with the sera from HBV-infected patients or tree shrews. Serum and liver samples of the inoculated animals were periodically collected and analyzed using fluorescence quantitative polymerase chain reaction, enzyme-linked immunosorbent assay, Southern blot, and immunohistochemistry. Six tree shrews were confirmed and four were suspected as chronically HBV-infected for more than 48 (up to 228 weeks after inoculation, including three that had been inoculated with serum from a confirmed HBV-infected tree shrew. Conclusions Outbred neonatal tree shrews can be long-term chronically infected with HBV at a frequency comparable to humans. The model resembles human disease where also a smaller proportion of infected individuals develop chronic HBV related disease. This model might enable genetic and immunologic investigations which would allow determination of underlying molecular causes favoring susceptibility for chronic HBV infection and disease establishment vs. viral clearance.

Somatostatin-immunoreactive senile plaque-like structures in the frontal cortex and nucleus accumbens of aged tree shrews and Japanese macaques.

Science.gov (United States)

Yamashita, Akiko; Fuchs, Eberhard; Taira, Masato; Yamamoto, Takamitsu; Hayashi, Motoharu

2012-06-01

Previously, we demonstrated decreased expression of somatostatin mRNA in aged macaque brain, particularly in the prefrontal cortex. To investigate whether or not this age-dependent decrease in mRNA is related to morphological changes, we analyzed somatostatin cells in the cerebra of aged Japanese macaques and compared them with those in rats and tree shrews, the latter of which are closely related to primates. Brains of aged macaques, tree shrews, and rats were investigated by immunohistochemistry with special emphasis on somatostatin. We observed degenerating somatostatin-immunoreactive cells in the cortices of aged macaques and tree shrews. Somatostatin-immunoreactive senile plaque-like structures were found in areas 6 and 8 and in the nucleus accumbens of macaques, as well as in the nucleus accumbens and the cortex of aged tree shrews, where amyloid accumulations were observed. Somatostatin degenerations may be related to amyloid accumulations and may play roles in impairments of cognitive functions during aging. © 2012 John Wiley & Sons A/S.

The mole

CERN Multimedia

CERN PhotoLab

1974-01-01

The mole continued its way around the SPS ring ... and on 31 July emerged where it started from, having completed its 7 kilometre journey without ever veering more than a couple of centimetres from its schedule path.

Genome Stability Maintenance in Naked Mole-Rat.

Science.gov (United States)

Petruseva, I O; Evdokimov, A N; Lavrik, O I

2017-01-01

The naked mole-rat ( Heterocephalus glaber ) is one of the most promising models used to study genome maintenance systems, including the effective repair of damage to DNA. The naked mole-rat is the longest lived rodent species, which is extraordinarily resistant to cancer and has a number of other unique phenotypic traits. For at least 80% of its lifespan, this animal shows no signs of aging or any increased likelihood of death and retains the ability to reproduce. The naked mole-rat draws the heightened attention of researchers who study the molecular basis of lengthy lifespan and cancer resistance. Despite the fact that the naked mole-rat lives under genotoxic stress conditions (oxidative, etc.), the main characteristics of its genome and proteome are a high stability and effective functioning. Replicative senescence in the somatic cells of naked mole-rats is missing, while an additional p53/pRb-dependent mechanism of early contact inhibition has been revealed in its fibroblasts, which controls cell proliferation and its mechanism of arf- dependent aging. The unique traits of phenotypic and molecular adaptations found in the naked mole-rat speak to a high stability and effective functioning of the molecular machinery that counteract damage accumulation in its genome. This review analyzes existing results in the study of the molecular basis of longevity and high cancer resistance in naked mole-rats.

Identification and characterization of toll-like receptors (TLRs) in the Chinese tree shrew (Tupaia belangeri chinensis).

Science.gov (United States)

Yu, Dandan; Wu, Yong; Xu, Ling; Fan, Yu; Peng, Li; Xu, Min; Yao, Yong-Gang

2016-07-01

In mammals, the toll-like receptors (TLRs) play a major role in initiating innate immune responses against pathogens. Comparison of the TLRs in different mammals may help in understanding the TLR-mediated responses and developing of animal models and efficient therapeutic measures for infectious diseases. The Chinese tree shrew (Tupaia belangeri chinensis), a small mammal with a close relationship to primates, is a viable experimental animal for studying viral and bacterial infections. In this study, we characterized the TLRs genes (tTLRs) in the Chinese tree shrew and identified 13 putative TLRs, which are orthologs of mammalian TLR1-TLR9 and TLR11-TLR13, and TLR10 was a pseudogene in tree shrew. Positive selection analyses using the Maximum likelihood (ML) method showed that tTLR8 and tTLR9 were under positive selection, which might be associated with the adaptation to the pathogen challenge. The mRNA expression levels of tTLRs presented an overall low and tissue-specific pattern, and were significantly upregulated upon Hepatitis C virus (HCV) infection. tTLR4 and tTLR9 underwent alternative splicing, which leads to different transcripts. Phylogenetic analysis and TLR structure prediction indicated that tTLRs were evolutionarily conserved, which might reflect an ancient mechanism and structure in the innate immune response system. Taken together, TLRs had both conserved and unique features in the Chinese tree shrew. Copyright © 2016 Elsevier Ltd. All rights reserved.

Tree shrews (tupaia belangeri exhibit novelty preference in the novel location memory task with 24-hour retention periods.

Directory of Open Access Journals (Sweden)

Jayakrishnan H R Nair

2014-04-01

Full Text Available Novelty preference is pervasive in mammalian species, and describes an inherent tendency to preferentially explore novelty. The novel location memory task studied here assesses the ability of animals to form accurate memories of a spatial configuration, consisting of several identical objects placed within an arena. Tree shrews were first familiarized with a particular object configuration during several sessions, and then an object was displaced during a test session. Tree shrews exhibited enhanced exploration when confronted with this novel configuration. The most reliable indicator associated with novelty preference was an enhancement in directed exploration towards the novel object, although we also observed a non-specific overall increase in exploration in one experiment. During the test session, we also observed an exploration of the location, which had previously been occupied by the displaced object, an effect termed empty quadrant. Our behavioral findings suggest multiple stages of spatial memory formation in tree shrews that are associated with various forms of behavioral responses to novelty. Reduced novelty preference has been linked to major depressive disorder in human patients. Given the established social conflict depression model in tree shrews, we anticipate that the study of the neural circuits of novelty preference and their malfunction during depression may have implications for understanding or treating depression in humans.

Preliminary report of shrews and rodents in and around Lake ...

African Journals Online (AJOL)

Surveys during October 2004 and July 2005, in and around Lake Bogoria National Reserve, Kenya, collected evidence of nine rodent species, and one species of shrew. The diversity of small mammals live-trapped within a single habitat type was low compared to similar studies in Africa. The low diversity may be due to the ...

Effect of land cover, habitat fragmentation and ant colonies on the distribution and abundance of shrews in southern California

Science.gov (United States)

Laakkonen, Juha; Fisher, Robert N.; Case, Ted J.

2001-01-01

Because effects of habitat fragmentation and anthropogenic disturbance on native animals have been relatively little studied in arid areas and in insectivores, we investigated the roles of different land covers, habitat fragmentation and ant colonies on the distribution and abundance of shrews, Notiosorex crawfordi and Sorex ornatus, in southern California.Notiosorex crawfordi was the numerically dominant species (trap-success rate 0·52) occurring in 21 of the 22 study sites in 85% of the 286 pitfall arrays used in this study.Sorex ornatus was captured in 14 of the sites, in 52% of the arrays with a total trap-success rate of 0·2. Neither of the species was found in one of the sites.The population dynamics of the two shrew species were relatively synchronous during the 4–5-year study; the peak densities usually occurred during the spring. Precipitation had a significant positive effect, and maximum temperature a significant negative effect on the trap-success rate of S. ornatus.Occurrence and abundance of shrews varied significantly between sites and years but the size of the landscape or the study site had no effect on the abundance of shrews. The amount of urban edge had no significant effect on the captures of shrews but increased edge allows invasion of the Argentine ants, which had a highly significant negative impact on the abundance of N. crawfordi.At the trap array level, the percentage of coastal sage scrub flora had a significant positive, and the percentage of other flora had a significant negative effect on the abundance of N. crawfordi. The mean canopy height and the abundance of N. crawfordi had a significant positive effect on the occurrence of S. ornatus.Our study suggests that the loss of native coastal sage scrub flora and increasing presence of Argentine ant colonies may significantly effect the distribution and abundance of N. crawfordi. The very low overall population densities of both shrew species in most study sites make both species

Moles: Tool-Assisted Environment Isolation with Closures

Science.gov (United States)

de Halleux, Jonathan; Tillmann, Nikolai

Isolating test cases from environment dependencies is often desirable, as it increases test reliability and reduces test execution time. However, code that calls non-virtual methods or consumes sealed classes is often impossible to test in isolation. Moles is a new lightweight framework which addresses this problem. For any .NET method, Moles allows test-code to provide alternative implementations, given as .NET delegates, for which C# provides very concise syntax while capturing local variables in a closure object. Using code instrumentation, the Moles framework will redirect calls to provided delegates instead of the original methods. The Moles framework is designed to work together with the dynamic symbolic execution tool Pex to enable automated test generation. In a case study, testing code programmed against the Microsoft SharePoint Foundation API, we achieved full code coverage while running tests in isolation without an actual SharePoint server. The Moles framework integrates with .NET and Visual Studio.

Haematology, genotoxicity, enzymatic activity and histopathology as biomarkers of metal pollution in the shrew Crocidura russula

International Nuclear Information System (INIS)

Sanchez-Chardi, A.; Marques, C.C.; Gabriel, S.I.; Capela-Silva, F.; Cabrita, A.S.; Lopez-Fuster, M.J.; Nadal, J.; Mathias, M.L.

2008-01-01

Haematological (WBC, RBC, Hgb and Hct) and genotoxicity (MNT) parameters, hepatic enzymatic activities (GST, GPx and GR), and a histopathological evaluation of liver, kidneys and gonads were assessed as general biomarkers of metal pollution in the shrew Crocidura russula inhabiting a pyrite mining area. Specimens exposed to metals presented a few significant alterations when compared with reference animals: GST activity decreased; micronuclei increased; and evident liver alterations related to metal exposure were observed. On the basis of all the parameters studied, age was an important factor that partly explained the observed variation, whereas sex was the least important factor. Significant correlations were also found between heavy metal concentrations and biomarkers evaluated, demonstrating the great influence of these metals in the metabolic alterations. To the best of our knowledge, these data constitute the first measurements of a battery of biomarkers in shrews from a mine site and are among the few available for insectivorous mammals. - Metals from an abandoned pyrite mine produce alterations in haematological parameters, GST, MNT, and histopathology in shrews

A new species of small-eared shrew (Mammalia, Eulipotyphla, Cryptotis) from the Lacandona rain forest, Mexico

Science.gov (United States)

Guevara, Lázaro; Sánchez-Cordero, Víctor; León-Paniagua, Livia; Woodman, Neal

2014-01-01

The diversity and distribution of mammals in the American tropics remain incompletely known. We describe a new species of small-eared shrew (Soricidae, Cryptotis) from the Lacandona rain forest, Chiapas, southern Mexico. The new species is distinguished from other species of Cryptotis on the basis of a unique combination of pelage coloration, size, dental, cranial, postcranial, and external characters, and genetic distances. It appears most closely related to species in the Cryptotis nigrescens species group, which occurs from southern Mexico to montane regions of Colombia. This discovery is particularly remarkable because the new species is from a low-elevation habitat (approximately 90 m), whereas most shrews in the region are restricted to higher elevations, typically > 1,000 m. The only known locality for the new shrew is in one of the last areas in southern Mexico where relatively undisturbed tropical vegetation is still found. The type locality is protected by the Mexican government as part of the Yaxchilán Archaeological Site on the border between Mexico and Guatemala.

MOLES3: Implementing an ISO standards driven data catalogue

Directory of Open Access Journals (Sweden)

Graham A Parton

2015-02-01

Full Text Available ISO19156 Observations and Measurements (O&M provides a standardised framework for organising information about the collection of information about the environment.  Here we describe the implementation of a specialisation of O&M for environmental data, the Metadata Objects for Linking Environmental Sciences (MOLES3.MOLES3 provides support for organising information about data, and for user navigation around data holdings. The implementation described here, “CEDA-MOLES”, also supports data management functions for the Centre for Environmental Data Archival, CEDA. The previous iteration of MOLES (MOLES2 saw active use over five years, being replaced by CEDA-MOLES in late 2014. During that period important lessons were learnt both about the information needed, as well as how to design and maintain the necessary information systems. In this paper we review the problems encountered in MOLES2; how and why CEDA-MOLES was developed and engineered; the migration of information holdings from MOLES2 to CEDA-MOLES; and, finally, provide an early assessment of MOLES3 (as implemented in CEDA-MOLES and its limitations.Key drivers for the MOLES3 development included the necessity for improved data provenance, for further structured information to support ISO19115 discovery metadata  export (for EU INSPIRE compliance, and to provide appropriate fixed landing pages for Digital Object Identifiers (DOIs in the presence of evolving datasets. Key lessons learned included the importance of minimising information structure in free text fields, and the necessity to support as much agility in the information infrastructure as possible without compromising on maintainability both by those using the systems internally and externally (e.g. citing in to the information infrastructure, and those responsible for the systems themselves. The migration itself needed to ensure continuity of service and traceability of archived assets.

Taxonomy Icon Data: Javan tree shrew [Taxonomy Icon

Lifescience Database Archive (English)

Full Text Available Javan tree shrew Tupaia javanica Chordata/Vertebrata/Mammalia/Theria/Eutheria/etc. Tupaia_java...nica_L.png Tupaia_javanica_NL.png Tupaia_javanica_S.png Tupaia_javanica_NS.png http://bioscienced...bc.jp/taxonomy_icon/icon.cgi?i=Tupaia+javanica&t=L http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Tupaia+java...nica&t=NL http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Tupaia+javanica&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Tupaia+javanica&t=NS ...

Dynamic changes in DNA demethylation in the tree shrew (Tupaia belangeri chinensis) brain during postnatal development and aging.

Science.gov (United States)

Wei, Shu; Hua, Hai-Rong; Chen, Qian-Quan; Zhang, Ying; Chen, Fei; Li, Shu-Qing; Li, Fan; Li, Jia-Li

2017-03-18

Brain development and aging are associated with alterations in multiple epigenetic systems, including DNA methylation and demethylation patterns. Here, we observed that the levels of the 5-hydroxymethylcytosine (5hmC) ten-eleven translocation (TET) enzyme-mediated active DNA demethylation products were dynamically changed and involved in postnatal brain development and aging in tree shrews ( Tupaia belangeri chinensis ). The levels of 5hmC in multiple anatomic structures showed a gradual increase throughout postnatal development, whereas a significant decrease in 5hmC was found in several brain regions in aged tree shrews, including in the prefrontal cortex and hippocampus, but not the cerebellum. Active changes in Tet mRNA levels indicated that TET2 and TET3 predominantly contributed to the changes in 5hmC levels. Our findings provide new insight into the dynamic changes in 5hmC levels in tree shrew brains during postnatal development and aging processes.

Size evolution in Goodwin’s small-eared shrew, Cryptotis goodwini

Science.gov (United States)

Woodman, N.; Merritt, J.F.; Churchfield, S.; Hutterer, R.; Sheftel, B.A.

2005-01-01

Fossils of Cryptotis goodwini from Honduras indicate that body sizes of modern individuals average at least 18% larger than among members of the late Pleistocene population of this species. Palynological and other paleoenvironmental studies provide evidence that the Neotropical montane environments that these shrews inhabit were cooler and drier in the late Pleistocene than at present and supported communities of plants without modern analog. Therefore, the most likely cause of this change in size ultimately was related to climatic change at the end of the Pleistocene?but to what specific factors did the species respond? I examined the possibilities that this species changed in size: to accommodate a change in temperature regime; to escape from predators; as a response to a change in intensity of interspecific competition; to take advantage of a newly abundant food resource. Based on evidence from studies of modern communities of shrews and niche partitioning, I hypothesized that size evolution in C. goodwini was directly related to changes in the community of soil and soil-surface invertebrates upon which the species depends, specifically an increase in the availability of earthworms (Annelida).

CT diagnosis of invasive hydatidiform mole

International Nuclear Information System (INIS)

Lu Mingquan; Jiang Lina; Li Xianxing; Wang Peijun

2000-01-01

Objective: To investigate the CT features and the diagnostic value in invasive mole. Methods: Eleven cases (age, 30 to 53 years, mean 40 years) with invasive mole proved by operation and pathology were studied, including 3 cases during peri-menopausal period of eight months, ten months and twelve months respectively. All cases were scanned by CT and enhanced study was done. Results: All cases showed enlargement of uterus of varying degrees. On CT, the density of uterine cavity was similar to that of water, intermingled with spotty patchy and hazy circular isodense shadows. High density stripe-like bleeding foci were found in 3 cases. The outline of uterine cavity was locally disrupted in all case and the muscle layer was thickened in 3 cases. On enhanced CT scan, the lesions in the uterine cavity appeared markedly hyperdense, just like 'the crater' and the 'mole sign'. The muscle layers at the site of disruption showed inhomogeneous enhancement after contrast injection. Conclusion: The CT features of invasive mole are characteristic, with important diagnostic value, especially for those during peri-menopausal period

Subsurface Sampling and Sensing Using Burrowing Moles

Science.gov (United States)

Stoker, C. R.; Richter, L.; Smith, W. H.

2004-01-01

Finding evidence for life on Mars will likely require accessing the subsurface since the Martian surface is both hostile to life and to preservation of biosignatures due to the cold dry conditions, the strong W environment, and the presence of strong oxidants. Systems are needed to probe beneath the sun and oxidant baked surface of Mars and return samples to the surface for analysis or to bring the instrument sensing underground. Recognizing this need, the European Space Agency incorporated a small subsurface penetrometer or Mole onto the Beagle 2 Mars lander. Had the 2003 landing been successful, the Mole would have collected samples from 1-1.5 m depth and delivered them to an organic analysis instrument on the surface. The de- vice called the Planetary Underground Tool (PLUTO), also measured soil mechanical and thermophysical properties. Constrained by the small mass and volume allowance of the Beagle lander, the PLUTO mole was a slender cylinder only 2 cm diameter and 28 cm long equipped with a small sampling device designed to collect samples and bring them to the surface for analysis by other instrument. The mass of the entire system including deployment mechanism and tether was 1/2 kg. sensor package underground to make in situ measurements. The Mars Underground Mole (MUM) is a larger Mole based on the PLUTO design but incorporating light collection optics that interface to a fiber optic cable in the tether that transmits light to a combined stimulated emission Raman Spectrometer and Short Wave Infrared (SWIR) reflectance Spectrometer with sensitivity from 0.7 to 2.5 micrometers. This instrument is called the Dual Spectral Sensor and uses a Digital Array Scanning Interferometer as the sensor technology, a type of fourier transform interferometer that uses fixed element prisms and thus is highly rugged compared to a Michaelson interferometer. Due to the size limitations of an on-Mole instrument compartment, and the availability of a tether, the sensor head

Prevalence of Toxoplasma gondii in common moles (Talpa europaea)

NARCIS (Netherlands)

Krijger, I.M.; Cornelissen, J.B.W.J.; Wisselink, H.J.; Meerburg, B.G.

2014-01-01

Background The prevalence of Toxoplasma gondii in common moles, Talpa europaea, was investigated in order to determine whether moles can serve as an indicator species for T. gondii infections in livestock. Findings In total, 86 moles were caught from 25 different sites in the Netherlands. Five

Vietnam Revisited.

Science.gov (United States)

Esper, George

1990-01-01

Reflections of an Associated Press special correspondent on a return visit to Vietnam 15 years after the war. Discusses the social and economic impact of the war on Vietnam. Examines the plight of the Vietnamese who served in the U.S. military, discussing the problems of Amerasians. Recounts the efforts of U.S. veterans to rebuild Vietnam. (RW)

Improved starch digestion of sucrase deficient shrews treated with oral glucoamylase enzyme supplements

Science.gov (United States)

Although named because of its sucrose hydrolytic activity, this mucosal enzyme plays a leading role in starch digestion because of its maltase and glucoamylase activities. Sucrase deficient mutant shrews, Suncus murinus, were used as a model to investigate starch digestion in patients with Congenita...

A new species of small-eared shrew from Colombia and Venezuela (Mammalia: Soricomorpha: Soricidae: Genus Cryptotis)

Science.gov (United States)

Woodman, N.

2002-01-01

Populations of small-eared shrews inhabiting the northern Cordillera Oriental of Colombia and adjoining Venezuelan highlands in the vicinity of Paramo de Tama have been referred alternatively to Cryptotis thomssi or Cryptotis meridensis. Morphological and morphometrical study of this population indicates that it belongs to neither taxon, but represents a distinct, previously unrecognized species. I describe this new species as Cryptotis tamensis and redescribe C. meridensis. Recognition of the population at Paramo de Tama as a separate taxon calls into question the identities of populations of shrews currently represented only by single specimens from Cerro Pintado in the Sierra de Perija, Colombia, and near El Junquito in the coastal highlands of Venezuela.

Vietnam

International Development Research Centre (IDRC) Digital Library (Canada)

Cathy Egan

taken with the eager collaboration of Vietnam's government, have since ... social sciences; and environment and natural resource management) was ... deliberate and increasing openness to the world of trade, investment, and knowl- edge ... Vietnam design trade liberalization and competition policies (in part as preparation.

Diagnosis of hydatidiform mole by hysterography through transabdominal injection

Energy Technology Data Exchange (ETDEWEB)

Kim, Chung Kyu; Park, Chang Yun; Choi, Byung Sook [Yonsei University College of Medicine, Seoul (Korea, Republic of)

1972-03-15

Molar pregnancy presents a pathologic condition requiring surgery of the uterus promptly as possible although hydatidiform mole itself is a benign disease. In order to remove the mole as quickly as possible, early diagnosis is desirable. In actual practice, however, definite preoperative diagnosis by clinical manifestation is impossible since which is vague or altogether absent symptoms especially in first trimester. Hysterography by transabdominal injection is very valuable and easy procedure for accurate diagnosis of hydatidiform mole which shows typical honey combed, moth eaten or sponge pattern on roentgenography. We have experienced 68 cases of hydatidiform mole during last five and half years. Among them hysterography by transabdominal route was done on 26 cases and shows 96% diagnostic accuracy. One missed case was turned out to be missed abortion. The absence of accidents indicates the harmlessness of the method. We feel the best approach in making diagnosis of hydatidiform mole among clinically borderline and in conclusive for mole pregnancy and its differential diagnosis is by use of transabdominal hysterography.

Diagnosis of hydatidiform mole by hysterography through transabdominal injection

International Nuclear Information System (INIS)

Kim, Chung Kyu; Park, Chang Yun; Choi, Byung Sook

1972-01-01

Molar pregnancy presents a pathologic condition requiring surgery of the uterus promptly as possible although hydatidiform mole itself is a benign disease. In order to remove the mole as quickly as possible, early diagnosis is desirable. In actual practice, however, definite preoperative diagnosis by clinical manifestation is impossible since which is vague or altogether absent symptoms especially in first trimester. Hysterography by transabdominal injection is very valuable and easy procedure for accurate diagnosis of hydatidiform mole which shows typical honey combed, moth eaten or sponge pattern on roentgenography. We have experienced 68 cases of hydatidiform mole during last five and half years. Among them hysterography by transabdominal route was done on 26 cases and shows 96% diagnostic accuracy. One missed case was turned out to be missed abortion. The absence of accidents indicates the harmlessness of the method. We feel the best approach in making diagnosis of hydatidiform mole among clinically borderline and in conclusive for mole pregnancy and its differential diagnosis is by use of transabdominal hysterography

How does the greater white-toothed shrew, Crocidura russula, responds to long-term heavy metal contamination? - A case study

International Nuclear Information System (INIS)

Marques, Carla Cristina; Sanchez-Chardi, Alejandro; Gabriel, Sofia Isabel; Nadal, Jacint; Viegas-Crespo, Ana Maria; Luz Mathias, Maria da

2007-01-01

Heavy metals accumulation in parallel with the evaluation of physiological and biochemical effects resulting from continued metal exposure were considered here using for the first time the great white-toothed shrew Crocidura russula as an in vivo model. Shrews were originated from an abandoned lead/zinc mining area and from a reference area, both in Alentejo, southern Portugal. Hepatic contents of nickel, copper, zinc, cadmium, mercury and lead were quantified by Inductively Coupled Plasma Mass Spectrometer (ICP-MS). Haematological parameters (white blood cells, red blood cells, haemoglobin and haematocrit) were obtained in a Coulter Counter Analyser and biochemical markers of the redox balance (glutathione S-transferase, glutathione peroxidase, and glutathione reductase) activities were measured spectrophotometrically using a Duo-50 spectrophotometer. Compared with control animals, significantly higher concentration of hepatic cadmium (9.29 vs. 1.18 μg/g dry weight) and nickel (1.56 vs. 0.343 μg/g dry weight) were detected in the shrews collected in the mining area. However, no significant changes were observed on haematological or enzymatic parameters in animals exposed to metal pollution. The obtained results show that shrews are good bioaccumulators of toxic heavy metals, but very tolerant to their effects, revealing an interesting long-term adaptation to polluted environments. In addition, this study provides reference values for haematological parameters and antioxidant enzymes levels in C. russula, which may be relevant for comparative purposes in further studies

Leucism in Mexican small-eared shrew Cryptotis mexicana (Mammalia : Soricomorpha), endemic to Mexico

NARCIS (Netherlands)

Guevara, Lazaro; Ramirez-Chaves, Hector E.; Cervantes, Fernando A.

Leucism is the partial or complete reduction of the fur pigmentation where eyes and skin maintain their normal coloration. In this paper, we report the record of an individual of the endemic Mexican shrew Cryptotis mexicana from Veracruz, Mexico, that displays leucism. This lack of pigmentation,

The United States and Vietnam Relationship: Benefits and Challenges for Vietnam

Science.gov (United States)

2016-06-10

the current stage in their bilateral relations. The U.S.-Vietnam relationship has been increasingly cemented in the context of the contemporary...reach the current stage in their bilateral relations. The U.S.-Vietnam relationship has been increasingly cemented in the context of the contemporary...Major Exports to Vietnam aircraft, mining equipment, electronic machinery, steel wire, raw cotton, plastics Source: Mark E. Manyin, The Vietnam

Vietnam.

Science.gov (United States)

1984-05-01

Attention in this discussion of Vietnam is directed to the following: people; geography; history; government; the economy (agriculture and industry, trade and balance of payments); foreign relations; and relations between the US and Vietnam. In mid-1983 the population was estimated at 57,610,000 with an annual growth rate of 2.4%. Ethnic Vietnamese constitute almost 90% of the population. Various ethnic groups make up the remaining 10% of the population, with approximately 1.2 million Chinese being the most numerous and concentrated in southern Vietnam. The 2nd largest minority, the Montagnards (mountain tribesmen) comprise 2 main ethnolinguistic groups--Malayo Polynesia and Mon-Khmer. The most important political institution in Vietnam is the Vietnamese Communisty Party. All but 4 party Politburo members concurrently hold high positions in the government. The most important powers within the Vietnamese government, as opposed to the Communisty Party, are the executive agencies. Under the overly ambitious initial 5 year plan and the more conservative 1981-85 plan, the Vietnamese have made little progress in raising output and living standards beyond the levels of the 1960s. Guidelines of the 1981-85 plan call for attaining food self sufficiency, strengthening export and consumer industries, as well as the heavy industries that support them, and improving transport and energy production. The US does not have diplomatic relations with Vietnam.

Architectonic subdivisions of neocortex in the tree shrew (Tupaia belangeri)

OpenAIRE

Wong, Peiyan; Kaas, Jon H.

2009-01-01

Tree shrews are small mammals that bear some semblance to squirrels, but are actually close relatives of primates. Thus, they have been extensively studied as a model for the early stages of primate evolution. In the present study, subdivisions of cortex were reconstructed from brain sections cut in the coronal, sagittal or horizontal planes, and processed for parvalbumin (PV), SMI-32 immunopositive neurofilament protein epitopes, vesicle glutamate transporter 2 (VGluT2), free ionic zinc, mye...

Vietnam

International Nuclear Information System (INIS)

2001-12-01

This document presents the energy profile of Vietnam: energy organizations and policy; companies: Petrovietnam (oil), Vietgas (gas), Power Company 1, 2 and 3 (PC1, PC2, PC3) and Electricite du Vietnam (electric power), Vinacoal (coal); supplies (resources, electric power, oil, gas and coal); prices; consumption; projects and perspectives. (J.S.)

Environmental Impact Statement for Proposed Closure of Los Angeles Air Force Base, California and Relocation of Space Systems Division

Science.gov (United States)

1990-05-01

1. The slender- horned spine flower is a federally-listed endangered species. Because of the highly disturbed nature of the proposed sites, none of...deposit include deer, antelope, gazelle, horse, pig, camel, elephant, rhinoceros, hippopotamus, rabbit, beaver, mole, shrew, ground sloth, hedgehog

Placentation in mammals once grouped as insectivores

DEFF Research Database (Denmark)

Carter, Anthony; Enders, Allen

2009-01-01

nutrition involving columnar trophoblast cells. These range from areolae in moles through complexly folded hemophagous regions in tenrecs to the trophoblastic annulus in shrews. Of these placental characters, few offer support to current phylogenies. However, the case for placing hedgehogs and gymnures...

Structural Analysis Of CD59 Of Chinese Tree Shrew: A New Reference Molecule For Human Immune System Specific CD59 Drug Discovery.

Science.gov (United States)

Panda, Subhamay; Kumari, Leena; Panda, Santamay

2017-11-17

Chinese tree shrews (Tupaia belangeri chinensis) bear several characteristics that are considered to be very crucial for utilizing in animal experimental models in biomedical research. Subsequent to the identification of key aspects and signaling pathways in nervous and immune systems, it is revealed that tree shrews acquires shared common as well as unique characteristics, and hence offers a genetic basis for employing this animal as a prospective model for biomedical research. CD59 glycoprotein, commonly referred to as MAC-inhibitory protein (MAC-IP), membrane inhibitor of reactive lysis (MIRL), or protectin, is encoded by the CD59 gene in human beings. It is the member of the LY6/uPAR/alpha-neurotoxin protein family. With this initial point the objective of this study was to determine a comparative composite based structure of CD59 of Chinese tree shrew. The additional objective of this study was to examine the distribution of negatively and positively charged amino acid over molecular modeled structure, distribution of secondary structural elements, hydrophobicity molecular surface analysis and electrostatic potential analysis with the assistance of several bioinformatical analytical tools. CD59 Amino acid sequence of Chinese tree shrew collected from the online database system of National Centre for Biotechnology Information. SignalP 4.0 online server was employed for detection of signal peptide instance within the protein sequence of CD59. Molecular model structure of CD59 protein was generated by the Iterative Threading ASSEmbly Refinement (I-TASSER) suite. The confirmation for three-dimensional structural model was evaluated by structure validation tools. Location of negatively and positively charged amino acid over molecular modeled structure, distribution of secondary structural elements, and hydrophobicity molecular surface analysis was performed with the help of Chimera tool. Electrostatic potential analysis was carried out with the adaptive Poisson

Molecular Survey on Brucellosis in Rodents and Shrews - Natural Reservoirs of Novel Brucella Species in Germany?

Science.gov (United States)

Hammerl, J A; Ulrich, R G; Imholt, C; Scholz, H C; Jacob, J; Kratzmann, N; Nöckler, K; Al Dahouk, S

2017-04-01

Brucellosis is a widespread zoonotic disease introduced from animal reservoirs to humans. In Germany, bovine and ovine/caprine brucellosis were eradicated more than a decade ago and mandatory measures in livestock have been implemented to keep the officially brucellosis-free status. In contrast, surveillance of wildlife is still challenging, and reliable data on the prevalence of brucellae in small mammal populations do not exist. To assess the epidemiology of Brucella spp. in rodents and shrews, a molecular survey was carried out. A total of 537 rodents and shrews were trapped in four federal states located throughout Germany and investigated for the presence of Brucella. Using a two-step molecular assay based on the detection of the Brucella-specific bcsp31 and IS711 sequences in tissue samples, 14.2% (n = 76) of the tested animals were positive. These originated mainly from western and south-western Germany, where preliminary analyses indicate population density-dependent Brucella prevalence in voles (Myodes glareolus) and mice (Apodemus spp.). recA typing revealed a close relationship to a potentially novel Brucella species recently isolated from red foxes (Vulpes vulpes) in Austria. The molecular detection of brucellae in various rodent taxa and for the first time in shrew species shows that these animals may be naturally infected or at least have a history of exposure to Brucella spp. © 2015 Blackwell Verlag GmbH.

Hydatidiform mole in Aminu Kano teaching hospital, northwestern ...

African Journals Online (AJOL)

Background: Hydatidiform mole is a benign tumour of the trophoblast tissue and a relatively common gynaecological emergency. It could resolve spontaneously following evacuation, however 9-20% of patients with complete hydatidiform mole go on to have gestational trophoblast neoplasia. It is potentially curable once the ...

Sticky snack for sengis: The Cape rock elephant-shrew, Elephantulus edwardii (Macroscelidea), as a pollinator of the Pagoda lily, Whiteheadia bifolia (Hyacinthaceae)

Science.gov (United States)

Wester, Petra

2010-12-01

Following the recent discovery of rodent pollination in the Pagoda lily, Whiteheadia bifolia (Hyacinthaceae) in South Africa, now the Cape rock elephant-shrew, Elephantulus edwardii (Macroscelidea, Afrotheria) is reported as an additional pollinator. Elephant-shrews, live-trapped near W. bifolia plants, were released in two terraria, containing the plants. The animals licked nectar with their long and slender tongues while being dusted with pollen and touching the stigmas of the flowers with their long and flexible noses. The captured elephant-shrews had W. bifolia pollen in their faeces, likely as a result of grooming their fur as they visited the flowers without eating or destroying them. The animals mostly preferred nectar over other food. This is the first record of pollination and nectar consumption in the primarily insectivorous E. edwardii, contributing to the very sparse knowledge about the behaviour of this unique clade of African mammals, as well as pollination by small mammals.

Neural Progenitors in the Developing Neocortex of the Northern Tree Shrew (Tupaia belangeri Show a Closer Relationship to Gyrencephalic Primates Than to Lissencephalic Rodents

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Sebastian Römer

2018-04-01

Full Text Available The neocortex is the most complex part of the mammalian brain and as such it has undergone tremendous expansion during evolution, especially in primates. The majority of neocortical neurons originate from distinct neural stem and progenitor cells (NPCs located in the ventricular and subventricular zone (SVZ. Previous studies revealed that the SVZ thickness as well as the abundance and distribution of NPCs, especially that of basal radial glia (bRG, differ markedly between the lissencephalic rodent and gyrencephalic primate neocortex. The northern tree shrew (Tupaia belangeri is a rat-sized mammal with a high brain to body mass ratio, which stands phylogenetically mid-way between rodents and primates. Our study provides – for the first time – detailed data on the presence, abundance and distribution of bRG and other distinct NPCs in the developing neocortex of the northern tree shrew (Tupaia belangeri. We show that the developing tree shrew neocortex is characterized by an expanded SVZ, a high abundance of Pax6+ NPCs in the SVZ, and a relatively high percentage of bRG at peak of upper-layer neurogenesis. We further demonstrate that key features of tree shrew neocortex development, e.g., the presence, abundance and distribution of distinct NPCs, are closer related to those of gyrencephalic primates than to those of ferret and lissencephalic rodents. Together, our study provides novel insight into the evolution of bRG and other distinct NPCs in the neocortex development of Euarchontoglires and introduces the tree shrew as a potential novel model organism in the area of human brain development and developmental disorders.

CO2 Monitoring and Background Mole Fraction at Zhongshan Station, Antarctica

Directory of Open Access Journals (Sweden)

Yulong Sun

2014-09-01

Full Text Available Background CO2 mole fraction and seasonal variations, measured at Zhongshan station, Antarctica, for 2010 through 2013, exhibit the expected lowest mole fraction in March with a peak in November. Irrespective of wind direction, the mole fraction of CO2 distributes evenly after polluted air from station operations is removed from the data sets. The daily range of average CO2 mole fraction in all four seasons is small. The monthly mean CO2 mole fraction at Zhongshan station is similar to that of other stations in Antarctica, with seasonal CO2 amplitudes in the order of 384–392 µmol∙mol−1. The annual increase in recent years is about 2 µmol∙mol−1∙yr−1. There is no appreciable difference between CO2 mole fractions around the coast of Antarctica and in the interior, showing that CO2 observed in Antarctica has been fully mixed in the atmosphere as it moves from the north through the southern hemisphere.

Ultrasonographic findings of Myoma, H-mole and Missed abortion

International Nuclear Information System (INIS)

Huh, Nam Yoon; You, H. S.; Seong, K. J.; Park, C. Y.

1982-01-01

Ultrasonography is very important in the diagnosis of various kinds of diseases in Obsterics and Gynecology. It has high diagnostic accuracy in the diagnosis of pelvic masses and widely used for the detection of normal orpathologic pregnancy. But still it is difficult to differentiate degenerated myoma, H-mole and missed abortion by ultrasonography. So the authors analyzed the ultrasonographic findings of 81 patients with myoma(29 cases), H-mole(23 cases), and missed abortion(29 cases) and the results are as follows; 1. Diagnostic accuracy was 8.6% in myoma, 87% in H-mole and 89% in missed abortion. 2. The most typical ultrasonographic finding of myoma was obulated mass contour with nonhomogenous internal echo. 3. The most characteristic finding of H-mole was fine vesicular pattern internal echo with globular enlargement of uterus. 4. The most frequent finding of missed abortion was deformed gestational sac with or without remained fetal echo. 5. Clinical correlation was very important for accurate diagnosis, especially when differential diagnosis was very difficult between myoma with marked cystic degeneration, missed abortion with large distorted gestational sac and H-mole with severe degeneration

Social status and sex effects on neural morphology in Damaraland mole-rats, Fukomys damarensis.

Science.gov (United States)

Anyan, Jeff J; Seney, Marianne L; Holley, Amanda; Bengston, Lynn; Goldman, Bruce D; Forger, Nancy G; Holmes, Melissa M

2011-01-01

We previously reported that in a eusocial rodent, the naked mole-rat (Heterocephalus glaber), traditional neural sex differences were absent; instead, neural dimorphisms were associated with breeding status. Here we examined the same neural regions previously studied in naked mole-rats in a second eusocial species, the Damaraland mole-rat (Fukomys damarensis). Damaraland mole-rats live in social groups with breeding restricted to a small number of animals. However, colony sizes are much smaller in Damaraland mole-rats than in naked mole-rats and there is consequently less reproductive skew. In this sense, Damaraland mole-rats may be considered intermediate in social organization between naked mole-rats and more traditional laboratory rodents. We report that, as in naked mole-rats, breeding Damaraland mole-rats have larger volumes of the principal nucleus of the bed nucleus of the stria terminalis and paraventricular nucleus of the hypothalamus than do subordinates, with no effect of sex on these measures. Thus, these structures may play special roles in breeders of eusocial species. However, in contrast to what was seen in naked mole-rats, we also found sex differences in Damaraland mole-rats: volume of the medial amygdala and motoneuron number in Onuf's nucleus were both greater in males than in females, with no significant effect of breeding status. Thus, both sex and breeding status influence neural morphology in Damaraland mole-rats. These findings are in accord with the observed sex differences in body weight and genitalia in Damaraland but not naked mole-rats. We hypothesize that the increased sexual dimorphism in Damaraland mole-rats relative to naked mole-rats is related to reduced reproductive skew. 2011 S. Karger AG, Basel.

"The Taming of the Shrew." A Play Packet To Accompany "Elementary, My Dear Shakespeare."

Science.gov (United States)

Engen, Barbara; Campbell, Joy

Intended for use by elementary school teachers as a supplement to the book, "Elementary, My Dear Shakespeare," or for use by itself to produce one Shakespeare play, this play packet contains ready-to-reproduce materials for the production of "The Taming of the Shrew." Materials include: staging suggestions for scenery, props,…

Preservation of hippocampal neuron numbers and hippocampal subfield volumes in behaviorally characterized aged tree shrews

NARCIS (Netherlands)

Keuker, J.I.H.; de Biurrun, G.; Luiten, P.G.M.; Fuchs, E.

2004-01-01

Aging is associated with a decreased ability to store and retrieve information. The hippocampal formation plays a critical role in such memory processes, and its integrity is affected during normal aging. We used tree shrews (Tupaia belangeri) as an animal model of aging, because in many

Umbilical Cord-Derived Mesenchymal Stem Cells Relieve Hindlimb Ischemia through Enhancing Angiogenesis in Tree Shrews

Directory of Open Access Journals (Sweden)

Cunping Yin

2016-01-01

Full Text Available Hindlimb ischemia is still a clinical problem with high morbidity and mortality. Patients suffer from consequent rest pain, ulcers, cool limbs, and even amputation. Angiogenesis is a promising target for the treatment of ischemic limbs, providing extra blood for the ischemic region. In the present study, we investigated the role of umbilical cord-derived mesenchymal stem cells (UC-MSCs in regulating angiogenesis and relieving hindlimb ischemia. UC-MSCs were isolated from the umbilical cord of tree shrews. Angiography results showed that UC-MSCs injection significantly promoted angiogenesis in tree shrews. Moreover, the ankle brachial index, transcutaneous oxygen pressure, blood perfusion, and capillary/muscle fiber ratio were all markedly increased by the application of UC-MSCs. In addition, the conditioned culture of human umbilical vein endothelial cells using medium collected from UC-MSCs showed higher expression of angiogenic markers and improved migration ability. In short, the isolated UC-MSCs notably contributed to restoring blood supply and alleviating the symptoms of limb ischemia through enhancing angiogenesis.

Prevalence of zoonotic Bartonella species among rodents and shrews in Thailand.

Science.gov (United States)

Pangjai, Decha; Maruyama, Soichi; Boonmar, Sumalee; Kabeya, Hidenori; Sato, Shingo; Nimsuphan, Burin; Petkanchanapong, Wimol; Wootta, Wattanapong; Wangroongsarb, Piyada; Boonyareth, Maskiet; Preedakoon, Poom; Saisongkorh, Watcharee; Sawanpanyalert, Pathom

2014-03-01

We investigated the prevalence of Bartonella species in 10 rodent and one shrew species in Thailand. From February 2008 to May 2010, a total of 375 small animals were captured in 9 provinces in Thailand. Bartonella strains were isolated from 57 rodents (54 from Rattus species and 3 from Bandicota indica) and one shrew (Suncus murinus) in 7 of the 9 provinces, and identified to the species level. Sequence analysis of the citrate synthase and RNA polymerase β subunit genes identified the 58 isolates from each Bartonella-positive animal as B. tribocorum in 27 (46.6%) animals, B. rattimassiliensis in 17 (29.3%) animals, B. elizabethae in 10 (17.2%) animals and B. queenslandensis in 4 (6.9%) animals. R. norvegicus, R. rattus, and Suncus murinus carried B. elizabethae, which causes endocarditis in humans. The prevalence of Bartonella bacteremic animals by province was 42.9% of the animals collected in Phang Nga, 26.8% in Chiang Rai, 20.4% in Sa Kaeo, 16.7% in Nakhon Si Thammarat, 12.0% in Surat Thani, 9.1% in Mae Hong Son and Loei Provinces. These results indicate that Bartonella organisms are widely distributed in small mammals in Thailand and some animal species may serve as important reservoirs of zoonotic Bartonella species in the country. Crown Copyright © 2013. Published by Elsevier Ltd. All rights reserved.

MOLE 2.0: Advanced approach for analysis of biomacromolecular channels

OpenAIRE

Sehnal D.; Varekova R.S.; Berka K.; Pravda L.; Navratilova V.; Banas P.; Ionescu C.-M.; Otyepka M.; Koca J.

2013-01-01

Background Channels and pores in biomacromolecules (proteins, nucleic acids and their complexes) play significant biological roles, e.g., in molecular recognition and enzyme substrate specificity. Results We present an advanced software tool entitled MOLE 2.0, which has been designed to analyze molecular channels and pores. Benchmark tests against other available software tools showed that MOLE 2.0 is by comparison quicker, more robust and more versatile. As a new feature, MOLE 2.0 estimates ...

Enzyme activity, hormone concentration in tree shrew (Tupaia belangeri during cold acclimation

Directory of Open Access Journals (Sweden)

Lin Zhang

2012-08-01

Full Text Available Environmental factors play an important role in the seasonal adaptation of body mass and thermogenesis in wild small mammals. The tree shrew (Tupaia belangeri, is a unique species of small mammals which is origin of island in the Oriental realm. The present study was to test the hypothesis that ambient temperature was a cue to induce adjustments in body mass, energy intake, metabolism, uncoupling protein 1 (UCP1 in brown adipose tissue (BAT, and other biochemical characters of T. belangeri during cold exposure about 21 days. Our data demonstrate that cold acclimation induced a remarkable increase in body mass, a significant increase in energy intake and metabolic rate, and high expression of UCP1 in BAT of T. belangeri. Cold acclimation induced an increase in cytochrome c oxidase (COX and Thyroidhormones (T3/T4. These data supported that T. belangeri increased the body mass and increased energy intake and expenditure under cold acclimation. Increased expression of UCP1 was potentially involved in the regulation of energy metabolism and thermogenic capacity following cold acclimation. And it through changes in enzyme activity and hormone concentration under cold acclimation, and suggested temperature changes play an important role in the regulation of thermogenic capacity in tree shrew.

Long-wavelength (red) light produces hyperopia in juvenile and adolescent tree shrews.

Science.gov (United States)

Gawne, Timothy J; Ward, Alexander H; Norton, Thomas T

2017-11-01

In infant tree shrews, exposure to narrow-band long-wavelength (red) light, that stimulates long-wavelength sensitive cones almost exclusively, slows axial elongation and produces hyperopia. We asked if red light produces hyperopia in juvenile and adolescent animals, ages when plus lenses are ineffective. Animals were raised in fluorescent colony lighting (100-300 lux) until they began 13days of red-light treatment at 11 (n=5, "infant"), 35 (n=5, "juvenile") or 95 (n=5, "adolescent") days of visual experience (DVE). LEDs provided 527-749 lux on the cage floor. To control for the higher red illuminance, a fluorescent control group (n=5) of juvenile (35 DVE) animals was exposed to ∼975 lux. Refractions were measured daily; ocular component dimensions at the start and end of treatment and end of recovery in colony lighting. These groups were compared with normals (n=7). In red light, the refractive state of both juvenile and adolescent animals became significantly (Prefractions (0.6±0.3D) were normal. In red-treated juveniles the vitreous chamber was significantly smaller than normal (Plight-induced slowed growth and hyperopia in juvenile and adolescent tree shrews demonstrates that the emmetropization mechanism is still capable of restraining eye growth at these ages. Copyright © 2017 Elsevier Ltd. All rights reserved.

Placentation in mammals

DEFF Research Database (Denmark)

Carter, A M; Enders, A C

2016-01-01

but may nevertheless allow transfer from mother to fetus through the exocelom. Hemophagous areas with columnar trophoblast are paraplacental structures in carnivores and elephants but occur also within the placenta as in hyenas and moles. In shrews, it is the yolk sac that ingests and processes red cells...

Archaeological Sites Inventory of the High Priority Portions of Training Areas 1, 2, 3, 4, 5, 6, 11, 13, and H of the Pinon Canyon Maneuver Site, Las Animas County, Colorado

Science.gov (United States)

2007-03-18

badger, and porcupine . Small mammals and nongame mammals found in the area are snowshoe hare, squirrel, muskrat, weasel, ringtail, shrew, mole...often buying up water sources and allowing their herds to roam across public and private land. By the early 1920s most of the public land had been

Physics in Vietnam

International Nuclear Information System (INIS)

Altarelli, Monica Pepe

1994-01-01

Vietnam is a country in rapid evolution, opening up communications with the rest of world and encouraging foreign investors. Although there is more ground to make up, the heady mixture of communism and free market they are aiming for is along the same lines as China. Jean Tran Thanh Van , who left Vietnam about forty years ago, judged that it was the right time to bring together Western and Vietnamese physicists. He promoted and organized the ''Rencontres du Vietnam'' on high energy physics and cosmology, which from December 13-18 brought together about one hundred physicists, half from Vietnam and half from abroad, in Hanoi for an intense programme to review the status of particle physics and its deep implications for cosmology

Physics in Vietnam

Energy Technology Data Exchange (ETDEWEB)

Altarelli, Monica Pepe

1994-03-15

Vietnam is a country in rapid evolution, opening up communications with the rest of world and encouraging foreign investors. Although there is more ground to make up, the heady mixture of communism and free market they are aiming for is along the same lines as China. Jean Tran Thanh Van , who left Vietnam about forty years ago, judged that it was the right time to bring together Western and Vietnamese physicists. He promoted and organized the ''Rencontres du Vietnam'' on high energy physics and cosmology, which from December 13-18 brought together about one hundred physicists, half from Vietnam and half from abroad, in Hanoi for an intense programme to review the status of particle physics and its deep implications for cosmology.

SHORT REPORT

Science.gov (United States)

Gu, S. H.; Dormion, J.; Hugot, J.-P.; Yanagihara, R.

2014-01-01

SUMMARY Recent discovery of genetically distinct hantaviruses in shrews and moles (order Soricomorpha, family Soricidae and Talpidae) has challenged the conventional view that rodents serve as the principal reservoir hosts. Nova virus (NVAV), previously identified in archival liver tissue of a single European mole (Talpa europaea) from Hungary, represents one of the most highly divergent hantaviruses identified to date. To ascertain the spatial distribution and genetic diversity of NVAV, we employed RT–PCR to analyse lungs from 94 moles, captured in two locations in France, during October 2012 to March 2013. NVAV was detected in more than 60% of moles at each location, suggesting efficient enzootic virus transmission and confirming that this mole species serves as the reservoir host. Although the pathogenic potential of NVAV is unknown, the widespread geographical distribution of the European mole might pose a hantavirus exposure risk for humans. PMID:24044372

Carving out turf in a biodiversity hotspot: multiple, previously unrecognized shrew species co-occur on Java Island, Indonesia.

Science.gov (United States)

Esselstyn, Jacob A; Maharadatunkamsi; Achmadi, Anang S; Siler, Cameron D; Evans, Ben J

2013-10-01

In theory, competition among species in a shared habitat results in niche separation. In the case of small recondite mammals such as shrews, little is known about their autecologies, leaving open questions regarding the degree to which closely related species co-occur and how or whether ecological niches are partitioned. The extent to which species are able to coexist may depend on the degree to which they exploit different features of their habitat, which may in turn influence our ability to recognize them as species. We explored these issues in a biodiversity hotspot, by surveying shrew (genus Crocidura) diversity on the Indonesian island of Java. We sequenced portions of nine unlinked genes in 100-117 specimens of Javan shrews and incorporated homologous data from most known Crocidura species from other parts of island South-East Asia. Current taxonomy recognizes four Crocidura species on Java, including two endemics. However, our phylogenetic, population genetic and species delimitation analyses identify five species on the island, and all are endemic to Java. While the individual ranges of these species may not overlap in their entirety, we found up to four species living syntopically and all five species co-occurring on one mountain. Differences in species' body size, use of above ground-level habitats by one species and habitat partitioning along ecological gradients may have facilitated species diversification and coexistence. © 2013 John Wiley & Sons Ltd.

High molecular weight hyaluronan mediates the cancer resistance of the naked mole-rat

Science.gov (United States)

Tian, Xiao; Azpurua, Jorge; Hine, Christopher; Vaidya, Amita; Myakishev-Rempel, Max; Ablaeva, Julia; Mao, Zhiyong; Nevo, Eviatar; Gorbunova, Vera; Seluanov, Andrei

2013-01-01

The naked mole-rat displays exceptional longevity, with a maximum lifespan exceeding 30 years1–3. This is the longest reported lifespan for a rodent species and is especially striking considering the small body mass of the naked mole-rat. In comparison, a similarly sized house mouse has a maximum lifespan of 4 years4,5. In addition to their longevity, naked mole-rats show an unusual resistance to cancer. Multi-year observations of large naked mole-rat colonies did not detect a single incidence of cancer2,6. Here we identify a mechanism responsible for the naked mole-rat’s cancer resistance. We found that naked mole-rat fibroblasts secrete extremely high molecular weight hyaluronan (HA), which is over five times larger than human or mouse HA. This high molecular weight HA accumulates abundantly in naked mole rat tissues due to the decreased activity of HA-degrading enzymes and a unique sequence of hyaluronan synthase 2 (HAS2). Furthermore, the naked mole-rat cells are more sensitive to HA signaling, as the naked mole rat cells have a higher affinity to HA than the mouse or human cells. Perturbation of the signaling pathways sufficient for malignant transformation of mouse fibroblasts fails to transform naked mole-rat cells. However, once high molecular weight HA is removed by either knocking down HAS2 or overexpressing the HA-degrading enzyme, Hyal2, naked mole-rat cells become susceptible to malignant transformation and readily form tumors in mice. We speculate that naked mole-rats have evolved a higher concentration of HA in the skin to provide skin elasticity needed for life in underground tunnels. This trait may have then been co-opted to provide cancer resistance and longevity to this species. PMID:23783513

Vietnam: Historians at War

Science.gov (United States)

Moyar, Mark

2008-01-01

Although the Vietnam War ended more than thirty years ago, historians remain as divided on what happened as the American people were during the war. Mark Moyar maps the ongoing battle between "orthodox" and "revisionist" Vietnam War historians: the first group, those who depict Vietnam as a bad war that the United States should…

Vietnam

International Nuclear Information System (INIS)

2004-02-01

This document summarizes the main energy facts and data about Vietnam: institutions and energy policy, energy companies (Petrovietnam (oil), Vietgas (gas), Electricity of Vietnam (EVN), Vinacoal (coal)), energy production (resources, electricity, oil, natural gas, coal), energy prices (motor fuels and electricity), energy consumption, and future energy issues and prospects (exploitation of new fossil fuel resources, building of new refineries and power stations). The main economic, supply and demand, and energy balance indicators are summarized in tables and graphics. (J.S.)

Potential Economic Impacts of the Vietnam-Korea Free Trade Agreement on Vietnam

Directory of Open Access Journals (Sweden)

Thanh Hoan Phan

2016-03-01

Full Text Available This paper provides an assessment of the potential economic impacts of the Vietnam-Korea free trade agreement on Vietnam, by using general equilibrium modeling. The results show that Vietnam-Korea FTA will increase aggregate welfare for both countries in the long run. The most important gains accrue from better allocation of resources consequent to trade liberalization. All the sectoral differences and changes are consistent with the trade profiles of the two countries, and the long-run results are more pronounced than those of the short-run. In comparison with other ASEAN countries, the CGE analysis suggests that Vietnam's agriculture exports to Korea would especially rise in the long run. However, there will be strong competition in this sector among ASEAN members. Thus, an earlier conclusion of a comprehensive FTA with Korea is expected to be a good strategy for Vietnam, so as to avoid the direct competition with ASEAN members in the future.

Sleep in the Cape Mole Rat: A Short-Sleeping Subterranean Rodent.

Science.gov (United States)

Kruger, Jean-Leigh; Gravett, Nadine; Bhagwandin, Adhil; Bennett, Nigel C; Archer, Elizabeth K; Manger, Paul R

2016-01-01

The Cape mole rat Georychus capensis is a solitary subterranean rodent found in the western and southern Cape of South Africa. This approximately 200-gram bathyergid rodent shows a nocturnal circadian rhythm, but sleep in this species is yet to be investigated. Using telemetric recordings of the electroencephalogram (EEG) and electromyogram (EMG) in conjunction with video recordings, we were able to show that the Cape mole rat, like all other rodents, has sleep periods composed of both rapid eye movement (REM) and slow-wave (non-REM) sleep. These mole rats spent on average 15.4 h awake, 7.1 h in non-REM sleep and 1.5 h in REM sleep each day. Cape mole rats sleep substantially less than other similarly sized terrestrial rodents but have a similar percentage of total sleep time occupied by REM sleep. In addition, the duration of both non-REM and REM sleep episodes was markedly shorter in the Cape mole rat than has been observed in terrestrial rodents. Interestingly, these features (total sleep time and episode duration) are similar to those observed in another subterranean bathyergid mole rat, i.e. Fukomys mechowii. Thus, there appears to be a bathyergid type of sleep amongst the rodents that may be related to their environment and the effect of this on their circadian rhythm. Investigating further species of bathyergid mole rats may fully define the emerging picture of sleep in these subterranean African rodents. © 2016 S. Karger AG, Basel.

"The Taming of the Shrew": authority and love at the origin of the modern nuclear family

Directory of Open Access Journals (Sweden)

Antonella Piazza

2013-10-01

Full Text Available The lesson on William Shakespeare’s The Taming of the Shrew was written on occasion of the day against the astonishing number of women murdered by men especially men who pretended to love them. This phenomenon is not to be associated to a sort of archaic culture, but, on the contrary, it is related to modernity. In fact, violence and conflicts in a heterosexual couple come explicitly to the fore with and after the institution of the patriarchal nuclear family which at the origins of modernity posits love as the motivation of marriage and the formation of a family. Shakespeare and the Elizabethan theatre face the question both in tragedies and in comedies as in the case of The Taming of the Shrew where the shrew’s final monologue problematically sounds as the manifesto of the acknowledgment of the inferiority of women and so of the husband’s right to the woman’s subjection to her husband.

Central visual system of the naked mole-rat (Heterocephalus glaber).

Science.gov (United States)

Crish, Samuel D; Dengler-Crish, Christine M; Catania, Kenneth C

2006-02-01

Naked mole-rats are fossorial rodents native to eastern Africa that spend their lives in extensive subterranean burrows where visual cues are poor. Not surprisingly, they have a degenerated eye and optic nerve, suggesting they have poor visual abilities. However, little is known about their central visual system. To investigate the organization of their central visual system, we injected a neuronal tracer into the eyes of naked mole-rats and mice to compare the neural structures mediating vision. We found that the superior colliculus and lateral geniculate nucleus were severely atrophied in the naked mole-rat. The olivary pretectal nucleus was reduced but still retained its characteristic morphology, possibly indicating a role in light detection. In addition, the suprachiasmatic nucleus is well innervated and resembles the same structure in other rodents. The naked mole-rat appears to have selectively lost structures that mediate form vision while retaining structures needed for minimal entrainment of circadian rhythms. Similar results have been reported for other mole-rat species. Taken together, these data suggest that light detection may still play an important role in the lives of these "blind" animals: most likely for circadian entrainment or setting seasonal rhythms.

High-molecular-mass hyaluronan mediates the cancer resistance of the naked mole rat.

Science.gov (United States)

Tian, Xiao; Azpurua, Jorge; Hine, Christopher; Vaidya, Amita; Myakishev-Rempel, Max; Ablaeva, Julia; Mao, Zhiyong; Nevo, Eviatar; Gorbunova, Vera; Seluanov, Andrei

2013-07-18

The naked mole rat (Heterocephalus glaber) displays exceptional longevity, with a maximum lifespan exceeding 30 years. This is the longest reported lifespan for a rodent species and is especially striking considering the small body mass of the naked mole rat. In comparison, a similarly sized house mouse has a maximum lifespan of 4 years. In addition to their longevity, naked mole rats show an unusual resistance to cancer. Multi-year observations of large naked mole-rat colonies did not detect a single incidence of cancer. Here we identify a mechanism responsible for the naked mole rat's cancer resistance. We found that naked mole-rat fibroblasts secrete extremely high-molecular-mass hyaluronan (HA), which is over five times larger than human or mouse HA. This high-molecular-mass HA accumulates abundantly in naked mole-rat tissues owing to the decreased activity of HA-degrading enzymes and a unique sequence of hyaluronan synthase 2 (HAS2). Furthermore, the naked mole-rat cells are more sensitive to HA signalling, as they have a higher affinity to HA compared with mouse or human cells. Perturbation of the signalling pathways sufficient for malignant transformation of mouse fibroblasts fails to transform naked mole-rat cells. However, once high-molecular-mass HA is removed by either knocking down HAS2 or overexpressing the HA-degrading enzyme, HYAL2, naked mole-rat cells become susceptible to malignant transformation and readily form tumours in mice. We speculate that naked mole rats have evolved a higher concentration of HA in the skin to provide skin elasticity needed for life in underground tunnels. This trait may have then been co-opted to provide cancer resistance and longevity to this species.

Ground sounds: Seismic detection in the golden mole

Science.gov (United States)

Narins, Peter M.; Lewis, Edwin R.

2004-05-01

The Namib Desert golden mole is a nocturnal, surface-foraging mammal, possessing a massively hypertrophied malleus which presumably confers low-frequency, substrate-vibration sensitivity through inertial bone conduction. Foraging trails are punctuated with characteristic sand disturbances in which the animal's head dips under the sand. The function of this behavior is not known but it is thought that it may be used to obtain a seismic fix on the next mound to be visited. To test this, we measured the local seismic vibrations both on the top of a mound and on the flats. The spectrum recorded on the flats shows a relatively low-amplitude peak at about 120 Hz, whereas the spectral peak recorded from the mound is nearly 17 dB greater in amplitude and centered at 310 Hz. This suggests that mounds act as seismic beacons for the golden moles that would be detectable from distances corresponding to typical intermound distances of 20-25 m. In addition, out of the 117 species for which data are available, these golden moles have the greatest ossicular mass relative to body size (Mason, personal communication). Functionally, they appear to be low-frequency specialists, and it is likely that golden moles hear through substrate conduction. [Work supported by NIH.

Conditioned flavor preference and the US postexposure effect in the house musk shrew (Suncus murinus

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Kosuke eSawa

2012-07-01

Full Text Available The house musk shrew (Suncus murinus is the only species of insectivore that can be used as a laboratory animal and is an interesting subject in terms of evolutional and comparative aspects. The present study on the learning faculties of shrews examines the possibility of acquiring a conditioned flavor preference and the effects of US postexposure. Subjects were allowed to a drink sucrose solution with flavor A and tap water with flavor B during training. Two extinction tests were administered after every four conditioning trials, and a significant preference for flavor A was observed. After each test, the animals were divided into two groups. Subjects in Group US were presented with a sucrose solution without flavor, while those in Group Water were given tap water. After these trials, all subjects received choice tests where they were presented with water containing the two flavors. The preference ratio was lower in Group US than in Group Water, suggesting a postexposure effect. The findings were discussed in terms of habituation to the US.

Assessment of naked mole-rat distribution and threats in Eastern Ethiopia

Directory of Open Access Journals (Sweden)

Mengistu Wale

2016-08-01

Full Text Available Objective: To identify the distribution, threats and community attitudes towards naked molerat in Eastern Ethiopia. Methods: Data were collected through direct observation and interview and Chi-square at 95% confidence interval was used for significance test. Results: Naked mole-rat was identified in Fafan, City/Shinele, Eastern Hararghe Zone and Dire Dawa Administrative. The main threats of naked mole-rat identified were agricultural expansion, human killing and lack of awareness. From a total of 100 respondents, 92% of them considered naked mole-rat as pest as a result that 46% of them participated in direct killing. Literacy rate significantly affects the willingness to participate in the conservation of naked mole-rat (χ2 = 7.478, df = 1, P < 0.05. From a total of 26% respondents who did not show the willingness to participate in the conservation, 80.8% of them were illiterate. Conclusions: Naked mole-rat is fairly common in many of the study sites. However, rapid shift from nomadic life style to cultivation of crops and lacks of awareness were the main threats of naked mole-rat. Therefore, since there is no conservation action currently, further comprehensive study is required to design conservation plan for this species.

A New Approach to the Shrew Group in Strange Tales from a Chinese Studio%《聊斋志异》悍妇群新论

Institute of Scientific and Technical Information of China (English)

张宇

2016-01-01

Shrews in Strange Tales from a Chinese Studio not only are great in number but also forms a complete picture of its group. In the past, studies on the shrews in this novel were from such aspects as views on marriage and religions, and the most typical views were to redress customs, reflect social practice and patri-archy projection. These theories, however, fail to satisfactorily explain the prevailing of shrews in this novel. Under the unique circumstances of Ming and Qing Dynasty, Pu Songling, the novelist, was deeply influenced by the ideology of “distinguishing Central China from its neighbors”, which has a profound influence on his literary works. As literacy inquisition occurred repeatedly in Qing Dynasty, writers had to seek a roundabout way to express his feeling. The group of shrews in Strange Tales from a Chinese Studio was thus formed. The novelist found his voice in the shrews and the shrews carry with them more symbolic meaning than realistic meaning. To know the symbolic meaning of the shrews helps readers understand Pu Songling and his literary recreation.%《聊斋志异》中的悍妇不仅数量众多，且可构成一体系完备的悍妇群。对《聊斋志异》悍妇的研究，多从婚姻观、宗教观角度分析，以“正风俗”、现实反映论以及男权投射论最为典型。然这些理论都不能尽解《聊斋志异》悍妇盛行之因。在明末清初特殊的社会背景下，蒲松龄深受“夷夏之辨”的思想意识影响，并深深影响其《聊斋志异》的创作；但清代文字狱迭发，抒发自己家国情怀，只能以迂回委婉的方式表达。悍妇便是这一家国情怀抒发的载体之一，其象征意义大于现实意义。了解悍妇的象征意义，对研究蒲松龄《聊斋志异》的创作有一定的意义。

Selective inflammatory pain insensitivity in the African naked mole-rat (Heterocephalus glaber).

Science.gov (United States)

Park, Thomas J; Lu, Ying; Jüttner, René; Smith, Ewan St J; Hu, Jing; Brand, Antje; Wetzel, Christiane; Milenkovic, Nevena; Erdmann, Bettina; Heppenstall, Paul A; Laurito, Charles E; Wilson, Steven P; Lewin, Gary R

2008-01-01

In all mammals, tissue inflammation leads to pain and behavioral sensitization to thermal and mechanical stimuli called hyperalgesia. We studied pain mechanisms in the African naked mole-rat, an unusual rodent species that lacks pain-related neuropeptides (e.g., substance P) in cutaneous sensory fibers. Naked mole-rats show a unique and remarkable lack of pain-related behaviors to two potent algogens, acid and capsaicin. Furthermore, when exposed to inflammatory insults or known mediators, naked mole-rats do not display thermal hyperalgesia. In contrast, naked mole-rats do display nocifensive behaviors in the formalin test and show mechanical hyperalgesia after inflammation. Using electrophysiology, we showed that primary afferent nociceptors in naked mole-rats are insensitive to acid stimuli, consistent with the animal's lack of acid-induced behavior. Acid transduction by sensory neurons is observed in birds, amphibians, and fish, which suggests that this tranduction mechanism has been selectively disabled in the naked mole-rat in the course of its evolution. In contrast, nociceptors do respond vigorously to capsaicin, and we also show that sensory neurons express a transient receptor potential vanilloid channel-1 ion channel that is capsaicin sensitive. Nevertheless, the activation of capsaicin-sensitive sensory neurons in naked mole-rats does not produce pain-related behavior. We show that capsaicin-sensitive nociceptors in the naked mole-rat are functionally connected to superficial dorsal horn neurons as in mice. However, the same nociceptors are also functionally connected to deep dorsal horn neurons, a connectivity that is rare in mice. The pain biology of the naked mole-rat is unique among mammals, thus the study of pain mechanisms in this unusual species can provide major insights into what constitutes "normal" mammalian nociception.

Selective inflammatory pain insensitivity in the African naked mole-rat (Heterocephalus glaber.

Directory of Open Access Journals (Sweden)

Thomas J Park

2008-01-01

Full Text Available In all mammals, tissue inflammation leads to pain and behavioral sensitization to thermal and mechanical stimuli called hyperalgesia. We studied pain mechanisms in the African naked mole-rat, an unusual rodent species that lacks pain-related neuropeptides (e.g., substance P in cutaneous sensory fibers. Naked mole-rats show a unique and remarkable lack of pain-related behaviors to two potent algogens, acid and capsaicin. Furthermore, when exposed to inflammatory insults or known mediators, naked mole-rats do not display thermal hyperalgesia. In contrast, naked mole-rats do display nocifensive behaviors in the formalin test and show mechanical hyperalgesia after inflammation. Using electrophysiology, we showed that primary afferent nociceptors in naked mole-rats are insensitive to acid stimuli, consistent with the animal's lack of acid-induced behavior. Acid transduction by sensory neurons is observed in birds, amphibians, and fish, which suggests that this tranduction mechanism has been selectively disabled in the naked mole-rat in the course of its evolution. In contrast, nociceptors do respond vigorously to capsaicin, and we also show that sensory neurons express a transient receptor potential vanilloid channel-1 ion channel that is capsaicin sensitive. Nevertheless, the activation of capsaicin-sensitive sensory neurons in naked mole-rats does not produce pain-related behavior. We show that capsaicin-sensitive nociceptors in the naked mole-rat are functionally connected to superficial dorsal horn neurons as in mice. However, the same nociceptors are also functionally connected to deep dorsal horn neurons, a connectivity that is rare in mice. The pain biology of the naked mole-rat is unique among mammals, thus the study of pain mechanisms in this unusual species can provide major insights into what constitutes "normal" mammalian nociception.

Adult neurogenesis and its anatomical context in the hippocampus of three mole-rat species

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Irmgard eAmrein

2014-05-01

Full Text Available African mole-rats (family Bathyergidae are small to medium sized, long-lived and strictly subterranean rodents that became valuable animal models as a result of their longevity and diversity in social organization. The formation and integration of new hippocampal neurons in adult mammals (adult hippocampal neurogenesis, AHN correlates negatively with age and positively with habitat complexity. Here we present quantitative data on AHN in wild-derived mole-rats of one year and older, and briefly describe its anatomical context including markers of neuronal function (calbindin and parvalbumin. Solitary Cape mole-rats (Georychus capensis, social highveld mole-rats (Cryptomys hottentotus pretoriae, and eusocial naked mole-rats (Heterocephalus glaber were assessed. Compared to other rodents, the hippocampal formation in mole-rats is small, but shows a distinct cytoarchitecture in the dentate gyrus and CA1. Distributions of the calcium-binding proteins differ from those seen in rodents; e.g., calbindin in CA3 of naked mole-rats distributes similar to the pattern seen in early primate development, and calbindin staining extends into the stratum lacunosum-moleculare of Cape mole-rats. Proliferating cells and young neurons are found in low numbers in the hippocampus of all three mole-rat species. Resident granule cell numbers are low as well. Proliferating cells expressed as a percentage of resident granule cells are in the range of other rodents, while the percentage of young neurons is lower than that observed in surface dwelling rodents. Between mole-rat species, we observed no difference in the percentage of proliferating cells. The percentages of young neurons are high in social highveld and naked mole-rats, and low in solitary Cape mole-rats. The findings support that proliferation is regulated independently of average life expectancy and habitat. Instead, neuronal differentiation reflects species-specific demands, which appear lower in subterranean

Adult neurogenesis and its anatomical context in the hippocampus of three mole-rat species.

Science.gov (United States)

Amrein, Irmgard; Becker, Anton S; Engler, Stefanie; Huang, Shih-Hui; Müller, Julian; Slomianka, Lutz; Oosthuizen, Maria K

2014-01-01

African mole-rats (family Bathyergidae) are small to medium sized, long-lived, and strictly subterranean rodents that became valuable animal models as a result of their longevity and diversity in social organization. The formation and integration of new hippocampal neurons in adult mammals (adult hippocampal neurogenesis, AHN) correlates negatively with age and positively with habitat complexity. Here we present quantitative data on AHN in wild-derived mole-rats of 1 year and older, and briefly describe its anatomical context including markers of neuronal function (calbindin and parvalbumin). Solitary Cape mole-rats (Georychus capensis), social highveld mole-rats (Cryptomys hottentotus pretoriae), and eusocial naked mole-rats (Heterocephalus glaber) were assessed. Compared to other rodents, the hippocampal formation in mole-rats is small, but shows a distinct cytoarchitecture in the dentate gyrus and CA1. Distributions of the calcium-binding proteins differ from those seen in rodents; e.g., calbindin in CA3 of naked mole-rats distributes similar to the pattern seen in early primate development, and calbindin staining extends into the stratum lacunosum-moleculare of Cape mole-rats. Proliferating cells and young neurons are found in low numbers in the hippocampus of all three mole-rat species. Resident granule cell numbers are low as well. Proliferating cells expressed as a percentage of resident granule cells are in the range of other rodents, while the percentage of young neurons is lower than that observed in surface dwelling rodents. Between mole-rat species, we observed no difference in the percentage of proliferating cells. The percentages of young neurons are high in social highveld and naked mole-rats, and low in solitary Cape mole-rats. The findings support that proliferation is regulated independently of average life expectancy and habitat. Instead, neuronal differentiation reflects species-specific demands, which appear lower in subterranean rodents.

The risk of persistent trophoblastic disease after hydatidiform mole classified by morphology and ploidy

DEFF Research Database (Denmark)

Niemann, Isa; Hansen, Estrid S; Sunde, Lone

2007-01-01

classifications, and compared the ability of the two classifications to discriminate between patients with and without a substantial risk of persistent trophoblastic disease. METHODS: 294 cases of consecutively collected hydropic placentas clinically suspected of hydatidiform mole made the basis......OBJECTIVE: Hydatidiform mole can be classified by histopathologic characteristics and by genetic constitutions and most complete moles are diploid, whereas most partial moles are triploid. We investigated the concordance between these two classifications, characterized moles with conflicting......-molar miscarriage, 20 were triploids, 2 were diploid androgenetic and 2 were diploid biparental. In 23% of the conceptuses, the histopathologic and genetic classifications were conflicting. 5% of the patients with hydropic placentas classified as partial mole encountered persistent trophoblastic disease; however...

Trading new neurons for status: Adult hippocampal neurogenesis in eusocial Damaraland mole-rats.

Science.gov (United States)

Oosthuizen, M K; Amrein, I

2016-06-02

Diversity in social structures, from solitary to eusocial, is a prominent feature of subterranean African mole-rat species. Damaraland mole-rats are eusocial, they live in colonies that are characterized by a reproductive division of labor and a subdivision into castes based on physiology and behavior. Damaraland mole-rats are exceptionally long lived and reproductive animals show delayed aging compared to non-reproductive animals. In the present study, we described the hippocampal architecture and the rate of hippocampal neurogenesis of wild-derived, adult Damaraland mole-rats in relation to sex, relative age and social status or caste. Overall, Damaraland mole-rats were found to have a small hippocampus and low rates of neurogenesis. We found no correlation between neurogenesis and sex or relative age. Social status or caste was the most prominent modulator of neurogenesis. An inverse relationship between neurogenesis and social status was apparent, with queens displaying the lowest neurogenesis while the worker mole-rats had the most. As there is no natural progression from one caste to another, social status within a colony was relatively stable and is reflected in the level of neurogenesis. Our results correspond to those found in the naked mole-rat, and may reflect an evolutionary and environmentally conserved trait within social mole-rat species. Copyright © 2016 IBRO. Published by Elsevier Ltd. All rights reserved.

The Lessons of the Vietnam War.

Science.gov (United States)

Starr, Jerold M., Ed.

This text book on the Vietnam War is to be used in teaching high students. Each of the volume's 12 chapters is a self-contained unit on an aspect of the War. The chapters are: (1) Introduction to Vietnam: land, history, and culture; (2) America at war in Vietnam: decisions and consequences; (3) Was the Vietnam War legal? (4) who fought for the…

High molecular weight hyaluronan mediates the cancer resistance of the naked mole-rat

OpenAIRE

Tian, Xiao; Azpurua, Jorge; Hine, Christopher; Vaidya, Amita; Myakishev-Rempel, Max; Ablaeva, Julia; Mao, Zhiyong; Nevo, Eviatar; Gorbunova, Vera; Seluanov, Andrei

2013-01-01

The naked mole-rat displays exceptional longevity, with a maximum lifespan exceeding 30 years 1–3 . This is the longest reported lifespan for a rodent species and is especially striking considering the small body mass of the naked mole-rat. In comparison, a similarly sized house mouse has a maximum lifespan of 4 years 4,5 . In addition to their longevity, naked mole-rats show an unusual resistance to cancer. Multi-year observations of large naked mole-rat colonies did not detect a single inci...

Diabetes in Vietnam.

Science.gov (United States)

Khue, Nguyen Thy

2015-01-01

The prevalence for diabetes, prediabetes, and gestational diabetes in Vietnam are low relative to other parts of the world, but they are increasing at alarming rates. These changes have occurred in the setting of economic and cultural transitions. The aim of this study was to provide relevant information depicting the diabetes burden in Vietnam. Literature was reviewed using PubMed and local Vietnamese sources, including papers published in the Vietnamese language. In 2012, the prevalence of diabetes was 5.4% and prediabetes 13.7%. In 2005, the prevalence of obesity was 1.7%. There is a dual burden of over- and undernutrition observed in Vietnam. Diabetes is associated with an increased waist-to-hip ratio despite normal body mass index. Nutritional transitions occurred with increased protein, fat, and fast foods, and with decreased fresh fruits and vegetables. Tobacco use is very high in Vietnam with 66% of adult men currently smoking. Challenges include endocrinology training, health care coverage, patient education, and lack of coordination among government and specialist agencies. Diabetes is a growing problem in Vietnam and is associated with obesity, changes in dietary patterns, and other cultural transitions. More research is needed to better understand this health care problem and to devise targeted interventions. Copyright © 2015 The Author. Published by Elsevier Inc. All rights reserved.

A Comparative Analysis of the Endocannabinoid System in the Retina of Mice, Tree Shrews, and Monkeys

DEFF Research Database (Denmark)

Bouskila, Joseph; Javadi, Pasha; Elkrief, Laurent

2016-01-01

is known about the distribution of the enzymes involved in the synthesis and degradation of these eCBs. We therefore examined the expression and localization of the main components of the eCB system in the retina of mice, tree shrews, and monkeys. We found that CB1R and FAAH distributions are well...

Blunted neuronal calcium response to hypoxia in naked mole-rat hippocampus.

Directory of Open Access Journals (Sweden)

Bethany L Peterson

Full Text Available Naked mole-rats are highly social and strictly subterranean rodents that live in large communal colonies in sealed and chronically oxygen-depleted burrows. Brain slices from naked mole-rats show extreme tolerance to hypoxia compared to slices from other mammals, as indicated by maintenance of synaptic transmission under more hypoxic conditions and three fold longer latency to anoxic depolarization. A key factor in determining whether or not the cellular response to hypoxia is reversible or leads to cell death may be the elevation of intracellular calcium concentration. In the present study, we used fluorescent imaging techniques to measure relative intracellular calcium changes in CA1 pyramidal cells of hippocampal slices during hypoxia. We found that calcium accumulation during hypoxia was significantly and substantially attenuated in slices from naked mole-rats compared to slices from laboratory mice. This was the case for both neonatal (postnatal day 6 and older (postnatal day 20 age groups. Furthermore, while both species demonstrated more calcium accumulation at older ages, the older naked mole-rats showed a smaller calcium accumulation response than even the younger mice. A blunted intracellular calcium response to hypoxia may contribute to the extreme hypoxia tolerance of naked mole-rat neurons. The results are discussed in terms of a general hypothesis that a very prolonged or arrested developmental process may allow adult naked mole-rat brain to retain the hypoxia tolerance normally only seen in neonatal mammals.

Blunted neuronal calcium response to hypoxia in naked mole-rat hippocampus.

Science.gov (United States)

Peterson, Bethany L; Larson, John; Buffenstein, Rochelle; Park, Thomas J; Fall, Christopher P

2012-01-01

Naked mole-rats are highly social and strictly subterranean rodents that live in large communal colonies in sealed and chronically oxygen-depleted burrows. Brain slices from naked mole-rats show extreme tolerance to hypoxia compared to slices from other mammals, as indicated by maintenance of synaptic transmission under more hypoxic conditions and three fold longer latency to anoxic depolarization. A key factor in determining whether or not the cellular response to hypoxia is reversible or leads to cell death may be the elevation of intracellular calcium concentration. In the present study, we used fluorescent imaging techniques to measure relative intracellular calcium changes in CA1 pyramidal cells of hippocampal slices during hypoxia. We found that calcium accumulation during hypoxia was significantly and substantially attenuated in slices from naked mole-rats compared to slices from laboratory mice. This was the case for both neonatal (postnatal day 6) and older (postnatal day 20) age groups. Furthermore, while both species demonstrated more calcium accumulation at older ages, the older naked mole-rats showed a smaller calcium accumulation response than even the younger mice. A blunted intracellular calcium response to hypoxia may contribute to the extreme hypoxia tolerance of naked mole-rat neurons. The results are discussed in terms of a general hypothesis that a very prolonged or arrested developmental process may allow adult naked mole-rat brain to retain the hypoxia tolerance normally only seen in neonatal mammals.

Fructose-driven glycolysis supports anoxia resistance in the naked mole-rat.

Science.gov (United States)

Park, Thomas J; Reznick, Jane; Peterson, Bethany L; Blass, Gregory; Omerbašić, Damir; Bennett, Nigel C; Kuich, P Henning J L; Zasada, Christin; Browe, Brigitte M; Hamann, Wiebke; Applegate, Daniel T; Radke, Michael H; Kosten, Tetiana; Lutermann, Heike; Gavaghan, Victoria; Eigenbrod, Ole; Bégay, Valérie; Amoroso, Vince G; Govind, Vidya; Minshall, Richard D; Smith, Ewan St J; Larson, John; Gotthardt, Michael; Kempa, Stefan; Lewin, Gary R

2017-04-21

The African naked mole-rat's ( Heterocephalus glaber ) social and subterranean lifestyle generates a hypoxic niche. Under experimental conditions, naked mole-rats tolerate hours of extreme hypoxia and survive 18 minutes of total oxygen deprivation (anoxia) without apparent injury. During anoxia, the naked mole-rat switches to anaerobic metabolism fueled by fructose, which is actively accumulated and metabolized to lactate in the brain. Global expression of the GLUT5 fructose transporter and high levels of ketohexokinase were identified as molecular signatures of fructose metabolism. Fructose-driven glycolytic respiration in naked mole-rat tissues avoids feedback inhibition of glycolysis via phosphofructokinase, supporting viability. The metabolic rewiring of glycolysis can circumvent the normally lethal effects of oxygen deprivation, a mechanism that could be harnessed to minimize hypoxic damage in human disease. Copyright © 2017, American Association for the Advancement of Science.

Genome sequencing reveals insights into physiology and longevity of the naked mole rat

DEFF Research Database (Denmark)

Kim, Eun Bae; Fang, Xiaodong; Fushan, Alexey A

2011-01-01

The naked mole rat (Heterocephalus glaber) is a strictly subterranean, extraordinarily long-lived eusocial mammal. Although it is the size of a mouse, its maximum lifespan exceeds 30 years, making this animal the longest-living rodent. Naked mole rats show negligible senescence, no age......-related increase in mortality, and high fecundity until death. In addition to delayed ageing, they are resistant to both spontaneous cancer and experimentally induced tumorigenesis. Naked mole rats pose a challenge to the theories that link ageing, cancer and redox homeostasis. Although characterized...... by significant oxidative stress, the naked mole rat proteome does not show age-related susceptibility to oxidative damage or increased ubiquitination. Naked mole rats naturally reside in large colonies with a single breeding female, the 'queen', who suppresses the sexual maturity of her subordinates. They also...

Extreme hypoxia tolerance of naked mole-rat brain.

Science.gov (United States)

Larson, John; Park, Thomas J

2009-12-09

Mammalian brains have extremely high levels of aerobic metabolism and typically suffer irreversible damage after brief periods of oxygen deprivation such as occur during stroke or cardiac arrest. Here we report that brain tissue from naked mole-rats, rodents that live in a chronically low-oxygen environment, is remarkably resistant to hypoxia: naked mole-rat neurons maintain synaptic transmission much longer than mouse neurons and can recover from periods of anoxia exceeding 30 min. We suggest that brain tolerance to hypoxia may result from slowed or arrested brain development in these extremely long-lived animals.

Hydatidiform mole: age-related clinical presentation and high rate of severe complications in older women.

Science.gov (United States)

Mangili, Giorgia; Giorgione, Veronica; Gentile, Cinzia; Bergamini, Alice; Pella, Francesca; Almirante, Giada; Candiani, Massimo

2014-05-01

The purpose of this study was to demonstrate differences in clinical presentation of hydatidiform mole between women ≥40 years and younger women. Retrospective study. A tertiary referral unit in northern Italy. Three hundred and sixty-five women with hydatidiform mole were divided into group A (Clinical presentation between groups A and B was analyzed, also considering partial hydatidiform mole and complete hydatidiform mole. Differences in clinical presentation according to woman's age. In group B the diagnosis of hydatidiform mole at ≥12 gestational weeks was more frequent (p presented with vaginal bleeding (p clinical features of hydatidiform mole in women ≥40 years are different from those seen in younger women. Failures in the early detection of hydatidiform mole in older women may expose them to a higher rate of severe complications. © 2014 Nordic Federation of Societies of Obstetrics and Gynecology.

Metrics of a 'mole hole' against the Lobachevsky space background

International Nuclear Information System (INIS)

Tentyukov, M.N.

1994-01-01

'Classical' mole hole are the Euclidean metrics consisting of two large space regions connected by a throat. They are the instanton solutions of the Einstein equations. It is shown that for existence of mole holes in the general relativity theory it is required the energy-momentum tensor breaking energetic conditions. 9 refs., 7 figs

ÉTUDE DE CAS — Vietnam : Les communes du Vietnam ...

International Development Research Centre (IDRC) Digital Library (Canada)

16 déc. 2010 ... Les communes du Vietnam progressent grâce à l'information Au Vietnam, un système de suivi communautaire de la pauvreté s'appuie sur des enquêtes officielles afin de mieux cibler les pauvres. Les données supplémentaires permettent d'améliorer la vie des collectivités, celle des femmes en particulier.

Acanthocephala Parasite (Profilicollis spp.) Loads in Correlation to Pacific Mole Crab (Emerita analoga) Size

Science.gov (United States)

Cheng, T.; Huang, S.; Galathe, M.; Jenkins, M.; Ramirez, A.; Crosby, L.; Barrera, J.; FitzHoward, S.

2013-12-01

Since 2002, San Francisco Bay students have been conducting marine ecosystem monitoring through a joint project with the Long-term Monitoring Program and Experiential Training for Students (LiMPETS), in conjunction with the Gulf of Farallones National Marine Sanctuary. Each year students collect population and demographic data on Pacific mole crabs (Emerita analoga), an indicator species that lives in the sandy beach habitat in temperate regions along the Pacific Ocean. Pacific mole crabs are filter feeding crustaceans that inhabit the intertidal swash zone and are known to be an intermediate host for parasitic ';spiny-headed' worms in the phylum Acanthocephala (Profilicollis spp.). Sampling takes place during their reproductive period, which occurs from spring to fall, and includes measuring total body length of the Pacific mole crabs and dissecting them to determine presence of Acanthocephalan parasites. We hypothesize that due to larger body mass, larger Pacific mole crabs will have a greater number of Acanthocephala parasites.We conducted several analyses using the LiMPETS long-term data. Specifically, we compared body length, crab gender, and parasite abundance from Pacific mole crabs sampled from four beaches located in the county and city of San Francisco. Our results indicated that larger Pacific mole crabs do not necessarily have more parasites, but are more likely to have at least one parasite, while female Pacific mole crabs carrying eggs, have more parasites than males or females without eggs. We also found that parasite loads per mole crab was highest in the spring. Further analysis will be conducted to determine factors affecting Pacific mole crab parasite loads. Studying Pacific mole crabs help evaluate the health of California's intertidal systems and how human activities, geologic changes, and climate changes all make huge impacts to the intertidal ecosystems.

77 FR 20273 - Vietnam Veterans Day

Science.gov (United States)

2012-04-03

... showing a generation of veterans the respect and support of a grateful Nation. The Vietnam War is a story... with honor, and on March 29, 1973, the last of our troops left Vietnam. Yet, in one of the war's most... commemorate the 50-year anniversary of the Vietnam War. [[Page 20276

A Probabilistic Typhoon Risk Model for Vietnam

Science.gov (United States)

Haseemkunju, A.; Smith, D. F.; Brolley, J. M.

2017-12-01

Annually, the coastal Provinces of low-lying Mekong River delta region in the southwest to the Red River Delta region in Northern Vietnam is exposed to severe wind and flood risk from landfalling typhoons. On average, about two to three tropical cyclones with a maximum sustained wind speed of >=34 knots make landfall along the Vietnam coast. Recently, Typhoon Wutip (2013) crossed Central Vietnam as a category 2 typhoon causing significant damage to properties. As tropical cyclone risk is expected to increase with increase in exposure and population growth along the coastal Provinces of Vietnam, insurance/reinsurance, and capital markets need a comprehensive probabilistic model to assess typhoon risk in Vietnam. In 2017, CoreLogic has expanded the geographical coverage of its basin-wide Western North Pacific probabilistic typhoon risk model to estimate the economic and insured losses from landfalling and by-passing tropical cyclones in Vietnam. The updated model is based on 71 years (1945-2015) of typhoon best-track data and 10,000 years of a basin-wide simulated stochastic tracks covering eight countries including Vietnam. The model is capable of estimating damage from wind, storm surge and rainfall flooding using vulnerability models, which relate typhoon hazard to building damageability. The hazard and loss models are validated against past historical typhoons affecting Vietnam. Notable typhoons causing significant damage in Vietnam are Lola (1993), Frankie (1996), Xangsane (2006), and Ketsana (2009). The central and northern coastal provinces of Vietnam are more vulnerable to wind and flood hazard, while typhoon risk in the southern provinces are relatively low.

The naked mole-rat response to oxidative stress: just deal with it.

Science.gov (United States)

Lewis, Kaitlyn N; Andziak, Blazej; Yang, Ting; Buffenstein, Rochelle

2013-10-20

The oxidative stress theory of aging has been the most widely accepted theory of aging providing insights into why we age and die for over 50 years, despite mounting evidence from a multitude of species indicating that there is no direct relationship between reactive oxygen species (ROS) and longevity. Here we explore how different species, including the longest lived rodent, the naked mole-rat, have defied the most predominant aging theory. In the case of extremely long-lived naked mole-rat, levels of ROS production are found to be similar to mice, antioxidant defenses unexceptional, and even under constitutive conditions, naked mole-rats combine a pro-oxidant intracellular milieu with high, steady state levels of oxidative damage. Clearly, naked mole-rats can tolerate this level of oxidative stress and must have mechanisms in place to prevent its translation into potentially lethal diseases. In addition to the naked mole-rat, other species from across the phylogenetic spectrum and even certain mouse strains do not support this theory. Moreover, overexpressing or knocking down antioxidant levels alters levels of oxidative damage and even cancer incidence, but does not modulate lifespan. Perhaps, it is not oxidative stress that modulates healthspan and longevity, but other cytoprotective mechanisms that allow animals to deal with high levels of oxidative damage and stress, and nevertheless live long, relatively healthy lifespans. Studying these mechanisms in uniquely long-lived species, like the naked mole-rat, may help us tease out the key contributors to aging and longevity.

The Origin of the Mole Concept

Science.gov (United States)

Jensen, William B.

2004-01-01

German Chemist, August Wilhelm Hofmann first introduced the term "molar" (from the Latin moles, meaning "a large mass") into chemistry, around 1865. The particular use of the term molar gained currency in the physics literature, where it was in common use at least through the 1940s.

Bioaccumulation of lead, mercury, and cadmium in the greater white-toothed shrew, Crocidura russula, from the Ebro Delta (NE Spain); Sex- and age-dependent variation

Energy Technology Data Exchange (ETDEWEB)

Sanchez-Chardi, Alejandro [Departament de Biologia Animal (Vertebrats), Facultat de Biologia, Universitat de Barcelona, Avinguda Diagonal 645, 08028 Barcelona (Spain)]. E-mail: a.sanchez.chardi@ub.edu; Lopez-Fuster, Maria Jose [Departament de Biologia Animal (Vertebrats), Facultat de Biologia, Universitat de Barcelona, Avinguda Diagonal 645, 08028 Barcelona (Spain); Nadal, Jacint [Departament de Biologia Animal (Vertebrats), Facultat de Biologia, Universitat de Barcelona, Avinguda Diagonal 645, 08028 Barcelona (Spain)

2007-01-15

We quantified bioaccumulation of lead, mercury, and cadmium in bones from 105 greater white-toothed shrews (Crocidura russula) collected at the Ebro Delta, a polluted area, and the Medas Islands, a control site. Lead and mercury levels varied with site, age, and sex, although statistical significances depended on each factor. Globally, shrews from the polluted area exhibited significantly higher concentrations of Pb and Hg. Increment of Pb with age was particularly remarkable in wetland animals and was interpreted in relation to human activities, namely hunting. Unlike males, females from the Ebro Delta maintained low Hg levels, which were associated with gestation and lactation. Cadmium levels did not differ between sites, sexes, or ages. This study provides the first data on heavy metals in mammals from this wetland and suggests that C. russula is a good bioindicator of metal pollution. We concluded that sex and age may represent an important source of variation in the bioaccumulation of these metals in wild populations. - Bioaccumulation patterns of Pb and Hg reveal sex and age-related differences in the large bones of the greater white-toothed shrew from a polluted Mediterranean wetland.

Study on nuclear power introduction into Vietnam

International Nuclear Information System (INIS)

Vuong Huu Tan

2000-01-01

The report presents main results of the study on nuclear power introduction into Vietnam which have been carried out at Vietnam Atomic Energy Commission in collaboration with Ministry of Industry of Vietnam and other countries like Japan, Canada and Korea. The study covers all topics related to the nuclear power introduction into Vietnam such as electricity demands and supply, economics, finance, technology, safety, manpower, site selection etc. (author)

Doing Business in Vietnam

DEFF Research Database (Denmark)

Meyer, Klaus E.; Tran, Thi Thu Yen; Nguyen, Hung Vo

2005-01-01

still reflects inheritances from the central plan system, Vietnam today has a vibrant economy with small businesses springing up at every street corner. Foreign investors have been flogging to Vietnam since the early 1990s, with a new peak of FDI inflow in 2004. This paper reviews the Vietnamese economy...

For Mole Problems, Call Avogadro: 602-1023

Science.gov (United States)

Uthe, R. E.

2002-10-01

General education students who have never encountered Avogadro’s number often have difficulty grasping its magnitude and the resulting implications for sizes and numbers of particles in common materials they see around them. I have surveyed the approaches used by several chemical educators. This article describes the techniques I find best help introductory students in General College at the University of Minnesota become familiar with Avogadro’s number and mole calculations. They involve estimating numbers of common objects and then calculating the length of time needed to count large numbers of them. For example, the immense amount of time required to count a mole of sand grains at one grain per second greatly exceeds the age of the universe. The calculations also reinforce procedures for manipulating exponents and applying problem-solving techniques.

Early embryonic development and transplantation in tree shrews

Directory of Open Access Journals (Sweden)

Lan-Zhen YAN

2016-07-01

Full Text Available As a novel experimental animal model, tree shrews have received increasing attention in recent years. Despite this, little is known in regards to the time phases of their embryonic development. In this study, surveillance systems were used to record the behavior and timing of copulations; embryos at different post-copulation stages were collected and cultured in vitro; and the developmental characteristics of both early-stage and in vitro cultured embryos were determined. A total of 163 females were collected following effective copulation, and 150 were used in either unilateral or bilateral oviduct embryo collections, with 307 embryos from 111 females obtained (conception rate=74%. Among them, 237 embryos were collected from 78 females, bilaterally, i.e., the average embryo number per female was 3.04; 172 fertilized eggs collected from 55 females, bilaterally, were cultured for 24-108 h in vitro for developmental observations; finally, 65 embryos from 23 bilateral cases and 70 embryos from 33 unilateral cases were used in embryo transplantation.

Ariosto, Gascoigne e The Taming of the Shrew

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Domenico Lovascio

2010-04-01

Full Text Available The essay aims to offer a thorough analysis of the influence exerted by Ludovico Ariosto’s I Suppositi on William Shakespeare’s The Taming of The Shrew through George Gascoigne’s translation, Supposes, and to underscore how crucial a painstaking study of sources can prove to the understanding, in a historical perspective, of the depth and complexity of Shakespeare’s theatre. First, the article briefly introduces the Italian commedia erudita and I Suppositi, and examines the changes to the source text made in translation by Gascoigne. Then, a survey is provided of some of the most important critical stances on the topic. Finally, an analysis of the various elements which Shakespeare borrowed from his source (characters, plot, verbal echoes shows how he refashioned them in order to expand their dramatic potential as well as to make his comedy an apt ground for reflection on ethical themes of great topicality in Elizabethan society.

Abundance & distribution of trombiculid mites & Orientia tsutsugamushi, the vectors & pathogen of scrub typhus in rodents & shrews collected from Puducherry & Tamil Nadu, India.

Science.gov (United States)

Candasamy, Sadanandane; Ayyanar, Elango; Paily, Kummankottil; Karthikeyan, Patricia Anitha; Sundararajan, Agatheswaran; Purushothaman, Jambulingam

2016-12-01

Human cases of scrub typhus are reported every year from Puducherry and adjoining areas in southern India. However, information on the presence of causative agent, Orientia tsutsugamushi, and its vectors is lacking. Hence, the objective of the study was to find out the vector as well as pathogen distribution in rodents and shrews present in the scrub typhus-reported areas in southern India. Trombiculid mites were collected by combing rats and shrews collected using Sherman traps and identified to species level following standard taxonomical keys. The serum samples of the animals were used for Weil-Felix test and the clots containing blood cells were used for DNA extraction and polymerase chain reaction (PCR). A total of 181 animals comprising four rodent species and one shrew species were collected from 12 villages. High proportion of chiggers was collected from the shrew, Suncus murinus (79.1%) and Rattus rattus (47.6%). A total of 10,491 trombiculid mites belonging to nine species were collected. Leptotrombidium deliense, the known vector of scrub typhus pathogen, was the predominant species (71.0%) and the chigger (L. deliense) index was 41.1 per animal. Of the 50 animals screened for the pathogen, 28 showed agglutination against OX-K in Weil-Felix test indicating the presence of antibodies against O. tsutsugamushi, the causative agent of scrub typhus. PCR carried out with the DNA extracted from blood samples of two of the animals were positive for GroEl gene of O. tsutsugamushi. L. deliense index was well above the critical limit of chigger load, indicating that all the villages were receptive for high risk of transmission of scrub typhus to human. Pathogen positivity was higher among animals collected from villages recorded for higher chigger indices due to active transmission between the chigger mites and reservoir host animals. The results are suggestive of routine vector/pathogen surveillance at hot spots to initiate timely preventive measures.

Livestock grazing intensity affects abundance of Common shrews (Sorex araneus) in two meadows in Denmark

OpenAIRE

Schmidt, Niels M; Olsen, Henrik; Leirs, Herwig

2009-01-01

Abstract Background Current nature conservation in semi-natural grasslands often includes grazing and hay cutting, as well as the abandonment of draining. Semi-natural grassland and in particular meadows constitute important habitat type for a large number of animal species in today's fragmented and intensively cultivated landscape of Europe. Here we focus on the population characteristics of Common shrews Sorex araneus in relation to livestock grazing intensity in two wet meadows in western ...

Partial hydatidiform mole with false-negative urine human chorionic gonadatropin test in the emergency department.

Science.gov (United States)

Mundangepfupfu, Tichaendepi; Waseem, Muhammad

2014-03-01

Hydatidiform mole (molar pregnancy) is a benign tumor of placental trophoblastic cells, which release human chorionic gonadotropin (hCG). Several case reports have described complete hydatidiform moles with false-negative urine qualitative hCG tests. These negative pregnancy tests have been attributed to the hook effect. We report an unusual presentation of a partial mole and review an alternative explanation for the negative hCG test. As partial moles are usually not associated with a large proliferation of trophoblastic cells, levels of hCG are commonly negative and serum quantitative hCG was 1,094,950 mIU/mL. Pelvic ultrasonography showed a uterine cavity containing a soft-tissue mass with multiple cystic lesions and the hydatidiform mole was extracted with suction curettage. Tissue pathology confirmed partial hydatidiform mole. In addition to the hook effect, we present another possible explanation for the false-negative test; namely the inability of some assays to detect hCG-degradation products, which may be higher in clinical samples from patients with hydatidiform mole. This case underscores the importance of knowing the limitations of the commonly used hCG assays. Copyright © 2014 Elsevier Inc. All rights reserved.

45 CFR 506.10 - “Vietnam conflict” defined.

Science.gov (United States)

2010-10-01

... § 506.10 “Vietnam conflict” defined. Vietnam conflict refers to the period beginning February 28, 1961... “Vietnam conflict” for purposes of payment of interest on missing military service members' deposits in the... ending date for the Vietnam conflict for purposes of determining eligibility for compensation under 50 U...

Microvascularization in trigeminal ganglion of the common tree shrew (Tupaia glis).

Science.gov (United States)

Kongstaponkit, S; Pradidarcheep, W; Toutip, S; Chunhabundit, P; Somana, R

1997-01-01

Since there is only a limited number of studies of the blood supply to the trigeminal ganglion (TG) in mammalian species, the TG from 16 common tree shrews (Tupaia glis) were investigated by light microscope, transmission electron microscope (TEM) and the corrosion cast technique in conjunction with scanning electron microscope (SEM). It was found that the TG contained clusters of neurons in the peripheral region whereas the bundles of nerve fibers were located more centrally. Each ganglionic neuron had a concentric nucleus and was ensheathed by satellite cells. It was noted that blood vessels of a continuous type were predominantly found in the area where the neurons were densely located and were much less frequently observed in the area occupied by nerve fibers. With TEM, the TG was shown to be mainly associated with large neurons containing big nuclei and prominent nucleoli. The blood supply of the TG is derived from the most rostral branch of the pontine artery, from the stapedial artery or sometimes from the supraorbital artery, and from the accessory meningeal artery which is a branch of the maxillary artery passing through the foramen ovale. These arteries give off branches and become capillary networks in the ganglion before draining blood to the peripheral region. The veins at the medial border drained into the cavernous sinus directly or through the inferior hypophyseal vein, while those at the lateral side of the ganglion carried the blood into the pterygoid plexus via an accessory meningeal vein. The veins along the trigeminal nerve root joined the posterior part of the cavernous sinus. These studies establish a unique anatomical distribution of the TG blood supply in the tree shrew and the utility of the cast/SEM technique in discerning detailed features of the blood supply in the nervous system.

ACTIVITY PATTERNS IN THE MOLE-RATS TACHYORYCTES ...

African Journals Online (AJOL)

Heilophoblus spends over 50 % of the day out of its nest, Tachyoryctes, ..... Surface foraging through an open hole and mole-hill formation could be directly ..... Heliophobius fed at irregular intervals throughout the day and night (Jarvis, ...

The Naked Mole Rat Genome Resource: facilitating analyses of cancer and longevity-related adaptations.

Science.gov (United States)

Keane, Michael; Craig, Thomas; Alföldi, Jessica; Berlin, Aaron M; Johnson, Jeremy; Seluanov, Andrei; Gorbunova, Vera; Di Palma, Federica; Lindblad-Toh, Kerstin; Church, George M; de Magalhães, João Pedro

2014-12-15

The naked mole rat (Heterocephalus glaber) is an exceptionally long-lived and cancer-resistant rodent native to East Africa. Although its genome was previously sequenced, here we report a new assembly sequenced by us with substantially higher N50 values for scaffolds and contigs. We analyzed the annotation of this new improved assembly and identified candidate genomic adaptations which may have contributed to the evolution of the naked mole rat's extraordinary traits, including in regions of p53, and the hyaluronan receptors CD44 and HMMR (RHAMM). Furthermore, we developed a freely available web portal, the Naked Mole Rat Genome Resource (http://www.naked-mole-rat.org), featuring the data and results of our analysis, to assist researchers interested in the genome and genes of the naked mole rat, and also to facilitate further studies on this fascinating species. © The Author 2014. Published by Oxford University Press.

Short interspersed elements (SINEs) from insectivores. Two classes of mammalian SINEs distinguished by A-rich tail structure.

Science.gov (United States)

Borodulina, O R; Kramerov, D A

2001-10-01

Four tRNA-related SINE families were isolated from the genome of the shrew Sorex araneus (SOR element), mole Mogera robusta (TAL element), and hedgehog Mesechinus dauuricus (ERI-1 and ERI-2 elements). Each of these SINEs families is specific for a single Insectivora family: SOR, for Soricidae (shrews); TAL, for Talpidae (moles and desmans); ERI-1 and ERI-2, for Erinaceidae (hedgehogs). There is a long polypyrimidine region (TC-motif) in TAL, ERI-1, and ERI-2 elements located immediately upstream of an A-rich tail with polyadenylation signals (AATAAA) and an RNA polymerase III terminator (T(4-6)) or TCT(3-4)). Ten out of 14 analyzed mammalian tRNA-related SINE families have an A-rich tail similar to that of TAL, ERI-1, and ERI-2 elements. These elements were assigned to class T+. The other four SINEs including SOR element have no polyadenylation signal and transcription terminator in their A-rich tail and were assigned to class T-. Class T+ SINEs occur only in mammals, and most of them have a long polypyrimidine region. Possible models of retroposition of class T+ and T- SINEs are discussed.

Sociality and the telencephalic distribution of corticotrophin-releasing factor, urocortin 3, and binding sites for CRF type 1 and type 2 receptors: A comparative study of eusocial naked mole-rats and solitary Cape mole-rats.

Science.gov (United States)

Coen, Clive W; Kalamatianos, Theodosis; Oosthuizen, Maria K; Poorun, Ravi; Faulkes, Christopher G; Bennett, Nigel C

2015-11-01

Various aspects of social behavior are influenced by the highly conserved corticotrophin-releasing factor (CRF) family of peptides and receptors in the mammalian telencephalon. This study has mapped and compared the telencephalic distribution of the CRF receptors, CRF1 and CRF2 , and two of their ligands, CRF and urocortin 3, respectively, in African mole-rat species with diametrically opposed social behavior. Naked mole-rats live in large eusocial colonies that are characterized by exceptional levels of social cohesion, tolerance, and cooperation in burrowing, foraging, defense, and alloparental care for the offspring of the single reproductive female. Cape mole-rats are solitary; they tolerate conspecifics only fleetingly during the breeding season. The telencephalic sites at which the level of CRF1 binding in naked mole-rats exceeds that in Cape mole-rats include the basolateral amygdaloid nucleus, hippocampal CA3 subfield, and dentate gyrus; in contrast, the level is greater in Cape mole-rats in the shell of the nucleus accumbens and medial habenular nucleus. For CRF2 binding, the sites with a greater level in naked mole-rats include the basolateral amygdaloid nucleus and dentate gyrus, but the septohippocampal nucleus, lateral septal nuclei, amygdalostriatal transition area, bed nucleus of the stria terminalis, and medial habenular nucleus display a greater level in Cape mole-rats. The results are discussed with reference to neuroanatomical and behavioral studies of various species, including monogamous and promiscuous voles. By analogy with findings in those species, we speculate that the abundance of CRF1 binding in the nucleus accumbens of Cape mole-rats reflects their lack of affiliative behavior. © 2015 Wiley Periodicals, Inc.

AFLP diversity between the Novosibirsk and Tomsk chromosome races of the common shrew (Sorex araneus

Directory of Open Access Journals (Sweden)

Andrey Polyakov

2009-12-01

Full Text Available Genetic diversity between of the Novosibirsk and Tomsk chromosome races of the common shrew (Sorex araneus was analyzed using 39 polymorphic AFLP (amplified fragments length polymorphism markers. Exact and F-statistics tests for population differentiation demonstrated significant interracial difference in allele frequencies and significant subdivision between the races. The value of the genetic distance between the chromosome races observed in this study corresponds to that found between subspecies of mammals studied so far.

The Lessons of the Vietnam War: Unit 13. Teacher's Manual: Strategies and Resources for Teaching the Vietnam War.

Science.gov (United States)

Center for Social Studies Education, Pittsburgh, PA.

This teacher's manual is designed to accompany the curriculum "The Lessons of the Vietnam War." For each of 12 units of the curriculum, this manual suggests projects for student research and classroom activities. The 12 units are entitled: (1) Introduction to Vietnam: land, history and culture; (2) America at war in Vietnam: decisions and…

Hypersensitivity to contact inhibition provides a clue to cancer resistance of naked mole-rat.

Science.gov (United States)

Seluanov, Andrei; Hine, Christopher; Azpurua, Jorge; Feigenson, Marina; Bozzella, Michael; Mao, Zhiyong; Catania, Kenneth C; Gorbunova, Vera

2009-11-17

The naked mole-rat is the longest living rodent with a maximum lifespan exceeding 28 years. In addition to its longevity, naked mole-rats have an extraordinary resistance to cancer as tumors have never been observed in these rodents. Furthermore, we show that a combination of activated Ras and SV40 LT fails to induce robust anchorage-independent growth in naked mole-rat cells, while it readily transforms mouse fibroblasts. The mechanisms responsible for the cancer resistance of naked mole-rats were unknown. Here we show that naked mole-rat fibroblasts display hypersensitivity to contact inhibition, a phenomenon we termed "early contact inhibition." Contact inhibition is a key anticancer mechanism that arrests cell division when cells reach a high density. In cell culture, naked mole-rat fibroblasts arrest at a much lower density than those from a mouse. We demonstrate that early contact inhibition requires the activity of p53 and pRb tumor suppressor pathways. Inactivation of both p53 and pRb attenuates early contact inhibition. Contact inhibition in human and mouse is triggered by the induction of p27(Kip1). In contrast, early contact inhibition in naked mole-rat is associated with the induction of p16(Ink4a). Furthermore, we show that the roles of p16(Ink4a) and p27(Kip1) in the control of contact inhibition became temporally separated in this species: the early contact inhibition is controlled by p16(Ink4a), and regular contact inhibition is controlled by p27(Kip1). We propose that the additional layer of protection conferred by two-tiered contact inhibition contributes to the remarkable tumor resistance of the naked mole-rat.

Natural Setting and Vegetation of the Florida Panhandle. An Account of the Environments and Plant Communities of Northern Florida, West of the Suwannee River.

Science.gov (United States)

1986-01-01

burrowers in the panhandle are moles, mice, shrews, cotton rats, pocket gophers, gopher turtles , crayfish, ants, and earthworms. . The detrital feeders...applicability of the terms, primeval, original, and virgin for our vegetation suddenly becomes nebulous . ., l Nonetheless there remains an obvious...mechanism for soil disturbance in wiregrass lands with the possible exception of the burrowing of gopher turtles . Anthesis occurs 5-9 months following

Amount of substance and the proposed redefinition of the mole

Science.gov (United States)

Milton, M. J. T.; Mills, I. M.

2009-06-01

There has been considerable discussion about the merits of redefining four of the base units of the SI, including the mole. In this paper, the options for implementing a new definition for the mole based on a fixed value for the Avogadro constant are discussed. They are placed in the context of the macroscopic nature of the quantity amount of substance and the opportunity to introduce a system for molar and atomic masses with unchanged values and consistent relative uncertainties.

Helminth associations in white-toothed shrews Crocidura russula (Insectivora: Soricidae) from the Albufera Natural Park, Spain.

Science.gov (United States)

Portolés, Enrique; Granel, Pedro; Esteban, J Guillermo; Cabaret, Jacques

2004-06-01

The helminths of 218 white-toothed shrews from 29 sites in 2 biotopes in the Albufera Natural Park (Valencia, Spain) were examined from July 1990 to August 1991. An association analysis of helminths occurring at a prevalence of more than 4% was carried out for 4 species of cestodes located in the intestine (Hymenolepis pistillum, H. scalaris, H. tiara, and Pseudhymenolepis redonica) and 3 species of nematodes (Pseudophysaloptera sp. located in the stomach, Stammerinema rhopocephala larvae in the intestine and abdominal cavity, and Porrocaecum sp. in the thoracic and abdominal cavities). Bivariate (species pairs) versus multivariate analyses (associations within the entire set of species) were performed of presence-absence and of quantitative records (influence of intensity on associations). The associations were evaluated with respect to the sex and age of the host and to the sampling date and sites. The host and environment played a limited role, and the major determinant of species assemblage was phylogenetic. Positive associations were found among both the cestodes and the nematodes, whereas negative associations were found between cestodes and nematodes. The type of life cycle was probably the second greatest determinant of species associations. Nematodes using shrews as a paratenic host or as their definitive host were both positively associated.

Developing School Psychology in Vietnam

Science.gov (United States)

Le, Phuong; Hagans, Kristi; Powers, Kristin; Hass, Michael

2011-01-01

Like China, Vietnam is a communist country with increasingly capitalist economic policies. A fundamental change occurred in these policies with the enactment of Vietnam's "doi moi" (renovation) policy in 1986 that called for a "free market with socialist orientations." However, this economic modernization has inadvertently…

Invading and expanding: range dynamics and ecological consequences of the greater white-toothed shrew (Crocidura russula invasion in Ireland.

Directory of Open Access Journals (Sweden)

Allan D McDevitt

Full Text Available Establishing how invasive species impact upon pre-existing species is a fundamental question in ecology and conservation biology. The greater white-toothed shrew (Crocidura russula is an invasive species in Ireland that was first recorded in 2007 and which, according to initial data, may be limiting the abundance/distribution of the pygmy shrew (Sorex minutus, previously Ireland's only shrew species. Because of these concerns, we undertook an intensive live-trapping survey (and used other data from live-trapping, sightings and bird of prey pellets/nest inspections collected between 2006 and 2013 to model the distribution and expansion of C. russula in Ireland and its impacts on Ireland's small mammal community. The main distribution range of C. russula was found to be approximately 7,600 km2 in 2013, with established outlier populations suggesting that the species is dispersing with human assistance within the island. The species is expanding rapidly for a small mammal, with a radial expansion rate of 5.5 km/yr overall (2008-2013, and independent estimates from live-trapping in 2012-2013 showing rates of 2.4-14.1 km/yr, 0.5-7.1 km/yr and 0-5.6 km/yr depending on the landscape features present. S. minutus is negatively associated with C. russula. S. minutus is completely absent at sites where C. russula is established and is only present at sites at the edge of and beyond the invasion range of C. russula. The speed of this invasion and the homogenous nature of the Irish landscape may mean that S. minutus has not had sufficient time to adapt to the sudden appearance of C. russula. This may mean the continued decline/disappearance of S. minutus as C. russula spreads throughout the island.

Profile of Vietnam War Veterans (2015).

Data.gov (United States)

Department of Veterans Affairs — The Profile of Vietnam War Veterans uses the 2015 ACS to provide a view into the demographic characteristics and socioeconomic conditions of the Vietnam War Veteran...

Unraveling the message: insights into comparative genomics of the naked mole-rat.

Science.gov (United States)

Lewis, Kaitlyn N; Soifer, Ilya; Melamud, Eugene; Roy, Margaret; McIsaac, R Scott; Hibbs, Matthew; Buffenstein, Rochelle

2016-08-01

Animals have evolved to survive, and even thrive, in different environments. Genetic adaptations may have indirectly created phenotypes that also resulted in a longer lifespan. One example of this phenomenon is the preternaturally long-lived naked mole-rat. This strictly subterranean rodent tolerates hypoxia, hypercapnia, and soil-based toxins. Naked mole-rats also exhibit pronounced resistance to cancer and an attenuated decline of many physiological characteristics that often decline as mammals age. Elucidating mechanisms that give rise to their unique phenotypes will lead to better understanding of subterranean ecophysiology and biology of aging. Comparative genomics could be a useful tool in this regard. Since the publication of a naked mole-rat genome assembly in 2011, analyses of genomic and transcriptomic data have enabled a clearer understanding of mole-rat evolutionary history and suggested molecular pathways (e.g., NRF2-signaling activation and DNA damage repair mechanisms) that may explain the extraordinarily longevity and unique health traits of this species. However, careful scrutiny and re-analysis suggest that some identified features result from incorrect or imprecise annotation and assembly of the naked mole-rat genome: in addition, some of these conclusions (e.g., genes involved in cancer resistance and hairlessness) are rejected when the analysis includes additional, more closely related species. We describe how the combination of better study design, improved genomic sequencing techniques, and new bioinformatic and data analytical tools will improve comparative genomics and ultimately bridge the gap between traditional model and nonmodel organisms.

The Environmental Pollution In Vietnam Source Impact And Remedies

OpenAIRE

Tuan Anh Hoang; Nam Xuan Chu; Trung Van Tran

2017-01-01

Currently the environmental problems is one of the urgent problems for all countries in the world. Vietnam is among of 10 countries with the most polluted air in the world the health of people is affected by the non-guaranteed air quality in Vietnam. According to the EPI in 2015 Vietnam ranked 79 in the total of 132 countries in the overall environmental assessment. However the air pollution index Vietnam ranked 123. On the burden of disease due to environment Vietnam ranked 77. Therefore the...

Hypofunctional TrkA Accounts for the Absence of Pain Sensitization in the African Naked Mole-Rat.

Science.gov (United States)

Omerbašić, Damir; Smith, Ewan St J; Moroni, Mirko; Homfeld, Johanna; Eigenbrod, Ole; Bennett, Nigel C; Reznick, Jane; Faulkes, Chris G; Selbach, Matthias; Lewin, Gary R

2016-10-11

The naked mole-rat is a subterranean rodent lacking several pain behaviors found in humans, rats, and mice. For example, nerve growth factor (NGF), an important mediator of pain sensitization, fails to produce thermal hyperalgesia in naked mole-rats. The sensitization of capsaicin-sensitive TRPV1 ion channels is necessary for NGF-induced hyperalgesia, but naked mole-rats have fully functional TRPV1 channels. We show that exposing isolated naked mole-rat nociceptors to NGF does not sensitize TRPV1. However, the naked mole-rat NGF receptor TrkA displays a reduced ability to engage signal transduction pathways that sensitize TRPV1. Between one- and three-amino-acid substitutions in the kinase domain of the naked mole-rat TrkA are sufficient to render the receptor hypofunctional, and this is associated with the absence of heat hyperalgesia. Our data suggest that evolution has selected for a TrkA variant that abolishes a robust nociceptive behavior in this species but is still compatible with species fitness. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

Hypofunctional TrkA Accounts for the Absence of Pain Sensitization in the African Naked Mole-Rat

Directory of Open Access Journals (Sweden)

Damir Omerbašić

2016-10-01

Full Text Available The naked mole-rat is a subterranean rodent lacking several pain behaviors found in humans, rats, and mice. For example, nerve growth factor (NGF, an important mediator of pain sensitization, fails to produce thermal hyperalgesia in naked mole-rats. The sensitization of capsaicin-sensitive TRPV1 ion channels is necessary for NGF-induced hyperalgesia, but naked mole-rats have fully functional TRPV1 channels. We show that exposing isolated naked mole-rat nociceptors to NGF does not sensitize TRPV1. However, the naked mole-rat NGF receptor TrkA displays a reduced ability to engage signal transduction pathways that sensitize TRPV1. Between one- and three-amino-acid substitutions in the kinase domain of the naked mole-rat TrkA are sufficient to render the receptor hypofunctional, and this is associated with the absence of heat hyperalgesia. Our data suggest that evolution has selected for a TrkA variant that abolishes a robust nociceptive behavior in this species but is still compatible with species fitness.

A Mole for Warm Magnetic and Optical Measurements of LHC Dipoles

CERN Document Server

Bottura, L; Deferne, G; Glöckner, C; Jansen, H; Köster, A; Legrand, P; Rijllart, A; Sievers, P

2000-01-01

A new rotating coil probe (a mole) has been developed for the simultaneous measurement of the magnetic field and magnetic axis of warm superconducting LHC dipoles and associated corrector windings. The mole houses a radial rotating coil and travels inside the magnet aperture by means of an externally driven two-way traction belt. The coil is rotated by an on-board piezo motor, being tested in view of future devices for cold measurements as the only type of motor compatible with strong magnetic fields. A virtual light spot is generated in the coil center by a LED source. The position of this light spot is measured from the outside by a system including a telescope, a CCD camera and a DSP. Jigs on reference granite tables are used to transfer the optical measurements to the magnet fiducials. We describe here the main characteristics and performance of the mole

Records of Wenchengia (Lamiaceae) from Vietnam

Science.gov (United States)

Phillipson, Peter B; Suddee, Somran

2016-01-01

Abstract Background The monotypic genus Wenchengia (Lamiaceae) has been thought to be endemic to Hainan, China. This paper reports on historic records of Wenchengia alternifolia collected from Vietnam. The recent recuration and modernisation of the Paris herbarium greatly facilitated this discovery. New information During preparatory work supporting the account for the Lamiaceae of the Flora of Thailand, three specimens of Wenchengia from central Vietnam were found in the Herbarium of the Musuem National d'Histoire Naturelle in Paris (P), and subsequently two duplicates were found in the Herbarium at Kew (K, abbreviations following Thiers 2016). The specimens were collected in and before 1927 and it is not known if the species is still extant in Vietnam. Searches for extant populations should focus in the Ba Na Hills or Bach Ma National Park, central Vietnam. PMID:27660535

psychrometry: from partial pressures to mole fractions

African Journals Online (AJOL)

ES Obe

1980-03-01

Mar 1, 1980 ... as an ideal gas mixture. Partial pressures then become identical: to mole fractions and sets of psychometric parameters result from rather elementary thermodynamic relations. Search for more accurate data has long led to the realization that neither dry air nor pure water vapour behaves like an ideal gas,.

Distribution of vasopressin in the brain of the eusocial naked mole-rat.

Science.gov (United States)

Rosen, Greta J; De Vries, Geert J; Goldman, Sharry L; Goldman, Bruce D; Forger, Nancy G

2007-02-20

Naked mole-rats are eusocial rodents that live in large subterranean colonies in which one queen breeds with one to three males. All other animals are nonbreeding subordinates. The external features of male and female subordinates, including their genitalia, are remarkably monomorphic, as is their behavior. Because vasopressin (VP) is associated with social behaviors and sex differences in other species, its distribution in naked mole-rats was of interest. We used immunohistochemistry to examine VP in the brains of subordinate and breeding naked mole-rats of both sexes. As in other mammals, VP-immunoreactive (-ir) somata were found in the paraventricular (PVN) and supraoptic nuclei (SON) and VP-ir projections from these nuclei ran through the internal and external zone of the median eminence. However, naked mole-rats had very few VP-ir cells in the bed nucleus of the stria terminalis (BST) and none in the suprachiasmatic nucleus (SCN); the extensive network of fine-caliber VP-ir fibers usually seen in projection sites of the BST and SCN were also absent. Equally unexpected was the abundance of large-caliber VP-ir fibers in the dorsomedial septum. VP immunoreactivity was generally similar in all groups, with the exception of VP-ir cell number in the dorsomedial hypothalamus (DMH). Breeders had a population of labeled cells in the DMH that was absent, or nearly absent, in subordinates. Future studies on the function of VP in these areas are needed to determine how the atypical distribution of VP immunoreactivity relates to eusociality and the unusual physiology of naked mole-rats.

Dual mechanism of chromatin remodeling in the common shrew sex trivalent (XY 1Y 2

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Sergey N. Matveevsky

2017-11-01

Full Text Available Here we focus on the XY1Y2 condition in male common shrew Sorex araneus Linnaeus, 1758, applying electron microscopy and immunocytochemistry for a comprehensive analysis of structure, synapsis and behaviour of the sex trivalent in pachytene spermatocytes. The pachytene sex trivalent consists of three distinct parts: short and long synaptic SC fragments (between the X and Y1 and between the X and Y2, respectively and a long asynaptic region of the X in-between. Chromatin inactivation was revealed in the XY1 synaptic region, the asynaptic region of the X and a very small asynaptic part of the Y2. This inactive part of the sex trivalent, that we named the ‘head’, forms a typical sex body and is located at the periphery of the meiotic nucleus at mid pachytene. The second part or ‘tail’, a long region of synapsis between the X and Y2 chromosomes, is directed from the periphery into the nucleus. Based on the distribution patterns of four proteins involved in chromatin inactivation, we propose a model of meiotic silencing in shrew sex chromosomes. Thus, we conclude that pachytene sex chromosomes are structurally and functionally two different chromatin domains with specific nuclear topology: the peripheral inactivated ‘true’ sex chromosome regions (part of the X and the Y1 and more centrally located transcriptionally active autosomal segments (part of the X and the Y2.

Current situation of radiation protection in Vietnam

International Nuclear Information System (INIS)

Tran, Toan Ngoc

2008-01-01

Vietnam was one of the earliest countries, who applied ionizing radiation in medicine, since 1923, Dr. Marie Curie had supplied radium sources to Hanoi cancer hospital for radiotherapy. However, we did not give sufficient attention to radiation protection involving, e.g. technology, legislation, until 1980s. Recently with the strong support from International Atomic Energy Agency (IAEA) and Vietnam government nuclear technology has been strongly and widely developed in different branches and radiation protection situation in Vietnam has been improved step by step. Strategy for Peaceful Utilization of Atomic Energy up to 2020 approved by the prime minister on January 3th, 2006 confirms that nuclear power plant will be put in operation by 2020. To ensure the implementation of the strategy, the first priority should be given to radiation protection and nuclear safety. This paper presents shortly some activities of radiation safety in Vietnam. The requirements for developing this field in Vietnam are also discussed. (author)

New records of marine algae in Vietnam

Science.gov (United States)

Le Hau, Nhu; Ly, Bui Minh; Van Huynh, Tran; Trung, Vo Thanh

2015-06-01

In May, 2013, a scientific expedition was organized by the Vietnam Academy of Science and Technology (VAST) and the Far Eastern Branch of the Russian Academy of Sciences (FEBRAS) through the frame of the VAST-FEBRAS International Collaboration Program. The expedition went along the coast of Vietnam from Quang Ninh to Kien Giang. The objective was to collect natural resources to investigate the biological and biochemical diversity of the territorial waters of Vietnam. Among the collected algae, six taxa are new records for the Vietnam algal flora. They are the red algae Titanophora pikeana (Dickie) Feldmann from Cu Lao Xanh Island, Laurencia natalensis Kylin from Tho Chu Island, Coelothrix irregularis (Harvey) Børgesen from Con Dao Island, the green algae Caulerpa oligophylla Montagne, Caulerpa andamanensis (W.R. Taylor) Draisma, Prudhomme et Sauvage from Phu Quy Island, and Caulerpa falcifolia Harvey & Bailey from Ly Son Island. The seaweed flora of Vietnam now counts 833 marine algal taxa, including 415 Rhodophyta, 147 Phaeophyceae, 183 Chlorophyta, and 88 Cyanobacteria.

Accumulation of Methylmercury in Invertebrates and Masked Shrews (Sorex cinereus) at an Upland Forest-Peatland Interface in Northern Minnesota, USA.

Science.gov (United States)

Tavshunsky, Ilana; Eggert, Susan L; Mitchell, Carl P J

2017-12-01

Mercury (Hg) methylation is often elevated at the terrestrial-peatland interface, but methylmercury (MeHg) production at this "hot spot" has not been linked with in situ biotic accumulation. We examined total Hg and MeHg levels in peat, invertebrates and tissues of the insectivore Sorex cinereus (masked shrew), inhabiting a terrestrial-peatland ecotone in northern Minnesota, USA. Mean MeHg concentrations in S. cinereus (71 ng g -1 ) fell between concentrations measured in spiders (mean 70-140 ng g -1 ), and ground beetles and millipedes (mean 29-42 ng g -1 ). Methylmercury concentrations in S. cinereus increased with age and differed among tissues, with highest concentrations in kidneys and muscle, followed by liver and brain. Nearly all Hg in S. cinereus was in the methylated form. Overall, the high proportional accumulation of MeHg in peat at the site (3.5% total Hg as MeHg) did not lead to particularly elevated concentrations in invertebrates or shrews, which are below values considered a toxicological risk.

Role of immunoexpression of cyclin D1, D3, retinoblastoma (Rb mutant and clinical risk factors on complete mole as risk factors of persistent mole

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Yudi M Hidayat

2015-10-01

Full Text Available Introduction: Changes in complete hydatidiform mole (CHM that become persistent are difficult to handle because the malignant pathogenesis of CHM is still unclear. The growth of abnormal cells in CHM is thought to be caused by cell cycle abnormalities. Some components that play a role in this phase include cyclin D and retinoblastoma (Rb. The aim of our study was to determine the role of clinical risk factors, as well as cyclin D1, cyclin D3 and Rb-protein, in the occurrence of persistent moles. Materials and Method: This study involves 68 CHM cases at Dr. Hasan Sadikin Hospital from 2007–2011. The protein expression of cyclin D1, cyclin D3, and Rb were determined by immunohistochemistry. The results were analyzed by comparing the two groups of CHM that became persistent to those that returned to normal, as determined by a Mochizuki regression curve assessment. Results: 20 cases (29% of CHM became persistent and that 48 cases (71% returned to normal. Significant clinical variables were age (p 0.05. Conclusion: There is a strong relationship between clinical risk factors of age, excessive proliferation histopathology, serum βhCG levels ≥100,000 mU/mL, cyclin D1 and Rb mutations with the incidence of persistent moles after the evacuation of the CHM. We proposed a model to predict the risks of persistent moles with a cut-off point of 2.384, which can be used as a reference for patients with CHM.

Reproductive characteristics of the african pygmy hedgehog, atelerix albiventris.

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Bedford, J M; Mock, O B; Nagdas, S K; Winfrey, V P; Olson, G E

2000-09-01

To obtain further perspective on reproduction and particularly gamete function among so-called primitive mammals presently grouped in the Order Insectivora, we have examined the African hedgehog, Atelerix albiventris, in light of unusual features reported in shrews and moles. Atelerix proves to share many but not all of the characteristics seen in these other insectivores. The penis of Atelerix has a 'snail-like' form, but lacks the surface spines common in insectivores and a number of other mammals. Hedgehog spermatozoa display an eccentric insertion of the tail on the sperm head, and they manifest the barbs on the perforatorium that, in shrews, probably effect the initial binding of the sperm head to the zona pellucida. As a possible correlate, the structural matrix of the hedgehog acrosome comprises only two main components, as judged by immunoblotting, rather than the complex of peptides seen in the matrix of some higher mammals. The Fallopian tube of Atelerix is relatively simple; it displays only minor differences in width and in the arborized epithelium between the isthmus and ampulla, and shows no evidence of the unusual sperm crypts that characterize the isthmus or ampulla, depending on the species, in shrews and moles. In common with other insectivores, Atelerix appears to be an induced ovulator, as judged by the ovulation of some 6-8 eggs by about 23 h after injection of hCG. The dense cumulus oophorus appeared to have little matrix, in keeping with the modest dimensions of the tubal ampulla and, while it was not quite as discrete as that of soricids, it did show the same insensitivity to 0.5% (w/v) ovine or bovine hyaluronidase.

Training human resource for NPP in Vietnam

International Nuclear Information System (INIS)

Nguyen, Trung Tinh; Dam, Xuan Hiep

2008-01-01

Vietnam will establish the first NPP in the near future. With us the first important thing is the human resource, but now there is no university in Vietnam training nuclear engineers. In EPU (Electric Power University), now we are preparing for training nuclear engineers. In this paper, we review the nuclear man power and the way to train the high quality human resource for NPP and for other nuclear application in Vietnam. (author)

Demystifying Poverty Measurement in Vietnam

OpenAIRE

Demombynes, Gabriel; Hoang Vu, Linh

2015-01-01

This paper provides an overview of poverty measurement issues in Vietnam for the non-specialist. Vietnam has two main approaches to measuring poverty. An income-based approach is used by the Ministry of Labor, Invalids, and Social Affairs to generate a classification used for determining anti-poverty program eligibility as well as poverty monitoring over the short term. A separate consumpt...

Extended longevity of reproductives appears to be common in Fukomys mole-rats (Rodentia, Bathyergidae.

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Philip Dammann

Full Text Available African mole-rats (Bathyergidae, Rodentia contain several social, cooperatively breeding species with low extrinsic mortality and unusually high longevity. All social bathyergids live in multigenerational families where reproduction is skewed towards a few breeding individuals. Most of their offspring remain as reproductively inactive "helpers" in their natal families, often for several years. This "reproductive subdivision" of mole-rat societies might be of interest for ageing research, as in at least one social bathyergid (Ansell's mole-rats Fukomys anselli, breeders have been shown to age significantly slower than non-breeders. These animals thus provide excellent conditions for studying the epigenetics of senescence by comparing divergent longevities within the same genotypes without the inescapable short-comings of inter-species comparisons. It has been claimed that many if not all social mole-rat species may have evolved similar ageing patterns, too. However, this remains unclear on account of the scarcity of reliable datasets on the subject. We therefore analyzed a 20-year breeding record of Giant mole-rats Fukomys mechowii, another social bathyergid species. We found that breeders indeed lived significantly longer than helpers (ca. 1.5-2.2fold depending on the sex, irrespective of social rank or other potentially confounding factors. Considering the phylogenetic positions of F. mechowii and F. anselli and unpublished data on a third Fukomys-species (F. damarensis showing essentially the same pattern, it seems probable that the reversal of the classic trade-off between somatic maintenance and sexual reproduction is characteristic of the whole genus and hence of the vast majority of social mole-rats.

From Combat to Legacies: Novels of the Vietnam War.

Science.gov (United States)

Johannessen, Larry R.

1995-01-01

Discusses novels of the Vietnam War, their usefulness, and the interest they hold for students. Considers four categories of Vietnam novels: the Vietnam experience, the war at home, the refugee experience, and the war's effect on the next generation. (SR)

Maternal mortality in Vietnam in 1994-95.

Science.gov (United States)

Hieu, D T; Hanenberg, R; Vach, T H; Vinh, D Q; Sokal, D

1999-12-01

This report presents the first population-based estimates of maternal mortality in Vietnam. All the deaths of women aged 15-49 in 1994-95 in three provinces of Vietnam were identified and classified by cause. Maternal mortality was the fifth most frequent cause of death. The maternal mortality ratio was 155 deaths per 100,000 live births. This ratio compares with the World Health Organization's estimates of 430 such deaths globally and 390 for Asia. The maternal mortality ratio in the delta regions of these provinces was half that of the mountainous and semimountainous regions. Because a larger proportion of the Vietnamese population live in delta regions than elsewhere, the maternal mortality ratio for Vietnam as a whole may be lower than that of the three provinces studied. Maternal mortality is low in Vietnam primarily because a relatively high proportion of deliveries take place in clinics and hospitals, where few women die in childbirth. Also, few women die of the consequences of induced abortion in Vietnam because the procedure is legal and easily available.

Incidence and review of hydatidiform mole; chorioadenoma, destruens and chorio carcinoma in Mirza Kochek Khan Hospita

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Ghaffari V

1995-04-01

Full Text Available Initial management, incidence and review of hydatidiform mole, chorioadenoma and destruens and chorio carcinoma in Mirza Kochek khan hospital department of ob.gyn and gynecology oncology of women's hospital Tehran-Iran school of medicin from September 1985 to March 1990, 209 patients received primary management for hydatidiform mole at oncology department of Mirza Kochek Khan hospital medical school of Tehran Iran. All of these women HAD complete record available for analysis, of these, 167 women bydatidiform mole, 12 patients chorioadenoma-destruens 30 patients chorio carcinoma a survey was made of factors likely to provide an important clinical perspective patient aye and the status of pregnancy were noted. 41 patient only sharp curettage and 55 patients suction curettage to remove the hydatidiform mole. 97 patient require chemo terapy, suction curettage of the uterus is clearly the best means of management in the most cases their eyperince documents that hydatidiform mole is an high risk pregnancy that requires prompt and in tensive management.

Severe Hand Injuries Caused by a Mole Gun

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Serdar Düzgün

2017-10-01

Full Text Available Objective: Injuries by mole guns differ from other firearm injuries primarily because they are close-range, low-energy injuries that are highly contaminated owing to contact with contaminated surfaces and the presence of numerous residual foreign bodies within the wound. The aim of this article is to share our surgical experience regarding the repair of severe hand injuries caused by mole guns. Material and Methods: This retrospective study included 11 patients with hand injuries. Data obtained about the patients, including age, gender, dominant or non-dominant hand, injuries to all vital structures, and reconstructive procedures were assessed, categorized, and recorded. Results: Ten patients had defects in one or several common digital branches of the median nerve in areas ranging from the distal part of the carpal tunnel to the distal palmar crease. All patients had flexor and extensor tendon injuries in all fingers except for the first finger. Reconstruction of soft tissue and skin defects was carried out with an interpolation flap planned from a random-based subpectoral- paraumbilical region in five patients, a SCIA-based groin flap in four patients, a reverse-radial forearm flap in one patient, and an adipofascial flap planned from the forearm in one patient. Conclusion: Mole gun injuries typically include all structures of the hand, and repair procedures involve every anatomic structure of the hand. An early and effective surgical operation followed by prolonged and effective physical therapy protocols is vital for regaining the full spectrum of hand functions.

Environmental considerations in Vietnam's energy policy

International Nuclear Information System (INIS)

Bui, X.H.

2007-01-01

Energy conservation is at the centre of an environmental debate in Vietnam, whose rapidly growing economy in recent years has resulted in rising energy consumption and environmental degradation. This article reviewed the actual state of Vietnam's energy system, with consideration of the country's energy policies and their impact on the environment. Vietnam's energy resources consist of a vast network of rivers that hold potential for hydroelectric power; reserves that are proven to have oil, natural gas and coal; and, other renewable energy sources such as wind and solar energy. The energy sector plays a major role in the economic and social aspects of the country. Since its economic reform, coal and crude oil exports have brought in foreign money to the national revenue. Vietnam exploits four commercial types of energy, namely coal, oil, natural gas and hydroelectricity. These traditional energy sources play a major role in providing energy for the rural and mountainous regions in the country. The increase in energy demand in Vietnam is currently greater than that of its gross national product. The energy intensity in Vietnam is 1.5 times greater than that of Thailand, and twice the average world consumption. Energy demands are increasing at a regular rate due to a low rate of energy efficiency and to growth in industrialization and modernization. In addition, the government provides subsidies to the already low price of energy. It was concluded that although Vietnam has a low rate of energy consumption compared to other regions of the world, there exists a serious imbalance between energy use and economic and social growth. This imbalance could have a negative impact on fossil resources and the environment, especially if the high demand for energy is maintained. Presently, all negative impacts on the environment are related to the energy sector. An environmental assessment and strategic proposals to manage this problem locally and globally, have constituted the

Species interactions during diversification and community assembly in an island radiation of shrews.

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Jacob A Esselstyn

Full Text Available BACKGROUND: Closely related, ecologically similar species often have adjacent distributions, suggesting competitive exclusion may contribute to the structure of some natural communities. In systems such as island archipelagos, where speciation is often tightly associated with dispersal over oceanic barriers, competitive exclusion may prevent population establishment following inter-island dispersal and subsequent cladogenesis. METHODOLOGY/PRINCIPAL FINDINGS: Using a combination of tools, we test the hypothesis that the distributions of shrew (Crocidura species in the Philippines are the result of competitive exclusion preventing secondary invasion of occupied islands. We first compare ecological niche models between two widespread, allopatric species and find statistical support for their ecological similarity, implying that competition for habitat between these species is possible. We then examine dispersion patterns among sympatric species and find some signal for overdispersion of body size, but not for phylogenetic branch length. Finally, we simulate the process of inter-island colonization under a stochastic model of dispersal lacking ecological forces. Results are dependent on the geographic scope and colonization probability employed. However, some combinations suggest that the number of inter-island dispersal events necessary to populate the archipelago may be much higher than the minimum number of colonization events necessary to explain current estimates of species richness and phylogenetic relationships. If our model is appropriate, these results imply that alternative factors, such as competitive exclusion, may have influenced the process of inter-island colonization and subsequent cladogenesis. CONCLUSIONS/SIGNIFICANCE: We interpret the combined results as providing tenuous evidence that similarity in body size may prevent co-occurrence in Philippine shrews and that competitive exclusion among ecologically similar species, rather

Influence of elevation and forest type on community assemblage and species distribution of shrews in the central and southern Appalachian mountains

Science.gov (United States)

W. Mark Ford; Timothy S. McCay; Michael A. Menzel; W. David Webster; Cathryn H. Greenberg; John F. Pagels; Joseph F. Merritt; Joseph F. Merritt

2005-01-01

We analyzed shrew community data from 398,832 pitfall trapnights at 303 sites across the upper Piedmont, Blue Ridge, northern Ridge and Valley, southern Ridge and Valley, Cumberland Plateau and Allegheny Mountains and Plateau sections of the central and southern Appalachian Mountains from Alabama to Pennsylvania. The objectives of our research were to describe regional...

Women at war: The crucible of Vietnam.

Science.gov (United States)

Pless Kaiser, Anica; Kabat, Daniel H; Spiro, Avron; Davison, Eve H; Stellman, Jeanne Mager

2017-12-01

Relatively little has been written about the military women who served in Vietnam, and there is virtually no literature on deployed civilian women (non-military). We examined the experiences of 1285 American women, military and civilian, who served in Vietnam during the war and responded to a mail survey conducted approximately 25 years later in which they were asked to report and reflect upon their experiences and social and health histories. We compare civilian women, primarily American Red Cross workers, to military women stratified by length of service, describe their demographic characteristics and warzone experiences (including working conditions, exposure to casualties and sexual harassment), and their homecoming following Vietnam. We assess current health and well-being and also compare the sample to age- and temporally-comparable women in the General Social Survey (GSS), with which our survey shared some measures. Short-term (Vietnam experience as "highly stressful" than were career (>20 years; 12%) and civilian women (13%). Additional differences regarding warzone experiences, homecoming support, and health outcomes were found among groups. All military and civilian women who served in Vietnam were less likely to have married or have had children than women from the general population, χ 2 (8) = 643.72, p Vietnam reported better health than women in the other groups. Regression analyses indicated that long-term physical health was mainly influenced by demographic characteristics, and that mental health and PTSD symptoms were influenced by warzone and homecoming experiences. Overall, this paper provides insight into the experiences of the understudied women who served in Vietnam, and sheds light on subgroup differences within the sample.

Instrumented Moles for Planetary Subsurface Regolith Studies

Science.gov (United States)

Richter, L. O.; Coste, P. A.; Grzesik, A.; Knollenberg, J.; Magnani, P.; Nadalini, R.; Re, E.; Romstedt, J.; Sohl, F.; Spohn, T.

2006-12-01

Soil-like materials, or regolith, on solar system objects provide a record of physical and/or chemical weathering processes on the object in question and as such possess significant scientific relevance for study by landed planetary missions. In the case of Mars, a complex interplay has been at work between impact gardening, aeolian as well as possibly fluvial processes. This resulted in regolith that is texturally as well as compositionally layered as hinted at by results from the Mars Exploration Rover (MER) missions which are capable of accessing shallow subsurface soils by wheel trenching. Significant subsurface soil access on Mars, i.e. to depths of a meter or more, remains to be accomplished on future missions. This has been one of the objectives of the unsuccessful Beagle 2 landed element of the ESA Mars Express mission having been equipped with the Planetary Underground Tool (PLUTO) subsurface soil sampling Mole system capable of self-penetration into regolith due to an internal electro-mechanical hammering mechanism. This lightweight device of less than 900 g mass was designed to repeatedly obtain and deliver to the lander regolith samples from depths down to 2 m which would have been analysed for organic matter and, specifically, organic carbon from potential extinct microbial activity. With funding from the ESA technology programme, an evolved Mole system - the Instrumented Mole System (IMS) - has now been developed to a readiness level of TRL 6. The IMS is to serve as a carrier for in situ instruments for measurements in planetary subsurface soils. This could complement or even eliminate the need to recover samples to the surface. The Engineering Model hardware having been developed within this effort is designed for accommodating a geophysical instrument package (Heat Flow and Physical Properties Package, HP3) that would be capable of measuring regolith physical properties and planetary heat flow. The chosen design encompasses a two-body Mole

Perspectives on the Teaching of Vietnam.

Science.gov (United States)

Berman, David M.

1986-01-01

Too often seen through the lens of the United States experience in the Vietnam War, this article offers an alternative approach to teaching Vietnam through the development of a cultural and historical perspective. Provides a brief summary of literature on Vietnamese cultural history which is appropriate to high school students. (JDH)

Hydatidiform moles among patients with incomplete abortion in ...

African Journals Online (AJOL)

SHS

ated risk factors of HM among patients with incomplete abortion evacuated at Bugando Medical ... Konje E, Massinde A, Rambau P. Hydatidiform moles among patients with ... countries (North America, Australia, New Zealand and ... missed as the cause of abortion. .... and duration of cigarette smoking could not be elicited.

Burrow architecture of the Damaraland mole-rat ( Fukomys ...

African Journals Online (AJOL)

The burrow architecture (length, internal dimensions, fractal dimension of tunnel systems, number of nesting chambers and surface mounds) was investigated in the Damaraland mole-rat (Fukomys damarensis). A total of 31 animals were caught from five different colonies and their burrow systems were excavated in their ...

The molecular basis of acid insensitivity in the African naked mole-rat.

Science.gov (United States)

Smith, Ewan St John; Omerbašić, Damir; Lechner, Stefan G; Anirudhan, Gireesh; Lapatsina, Liudmila; Lewin, Gary R

2011-12-16

Acid evokes pain by exciting nociceptors; the acid sensors are proton-gated ion channels that depolarize neurons. The naked mole-rat (Heterocephalus glaber) is exceptional in its acid insensitivity, but acid sensors (acid-sensing ion channels and the transient receptor potential vanilloid-1 ion channel) in naked mole-rat nociceptors are similar to those in other vertebrates. Acid inhibition of voltage-gated sodium currents is more profound in naked mole-rat nociceptors than in mouse nociceptors, however, which effectively prevents acid-induced action potential initiation. We describe a species-specific variant of the nociceptor sodium channel Na(V)1.7, which is potently blocked by protons and can account for acid insensitivity in this species. Thus, evolutionary pressure has selected for an Na(V)1.7 gene variant that tips the balance from proton-induced excitation to inhibition of action potential initiation to abolish acid nociception.

Stress resistance in the naked mole-rat: the bare essentials - a mini-review.

Science.gov (United States)

Lewis, Kaitlyn N; Mele, James; Hornsby, Peter J; Buffenstein, Rochelle

2012-01-01

Studies comparing similar-sized species with disparate longevity may elucidate novel mechanisms that abrogate aging and prolong good health. We focus on the longest living rodent, the naked mole-rat. This mouse-sized mammal lives ~8 times longer than do mice and, despite high levels of oxidative damage evident at a young age, it is not only very resistant to spontaneous neoplasia but also shows minimal decline in age-associated physiological traits. We assess the current status of stress resistance and longevity, focusing in particular on the molecular and cellular responses to cytotoxins and other stressors between the short-lived laboratory mouse and the naked mole-rat. Like other experimental animal models of lifespan extension, naked mole-rat fibroblasts are extremely tolerant of a broad spectrum of cytotoxins including heat, heavy metals, DNA-damaging agents and xenobiotics, showing LD(50) values between 2- and 20-fold greater than those of fibroblasts of shorter-lived mice. Our new data reveal that naked mole-rat fibroblasts stop proliferating even at low doses of toxin whereas those mouse fibroblasts that survive treatment rapidly re-enter the cell cycle and may proliferate with DNA damage. Naked mole-rat fibroblasts also show significantly higher constitutive levels of both p53 and Nrf2 protein levels and activity, and this increases even further in response to toxins. Enhanced cell signaling via p53 and Nrf2 protects cells against proliferating with damage, augments clearance of damaged proteins and organelles and facilitates the maintenance of both genomic and protein integrity. These pathways collectively regulate a myriad of mechanisms which may contribute to the attenuated aging profile and sustained healthspan of the naked mole-rat. Understanding how these are regulated may be also integral to sustaining positive human healthspan well into old age and may elucidate novel therapeutics for delaying the onset and progression of physiological declines

Biological and biochemical properties of human chorionic gonadotropin from urine of patients with hydatidiform mole and its radioimmunoassay

International Nuclear Information System (INIS)

Nishimura, Ryuichiro; Hamamoto, Tamotsu; Tanabe, Keizo; Takemori, Masayuki; Ashitaka, Yoshihiko

1981-01-01

Human chorionic gonadotropin (hCG) was extracted and purified from the urine of four patients with hydatidiform mole. The immunological activities of the hCG-hydatidiform mole by hCG radioimmunoassay (RIA) ranged from 9,380 to 9,700 IU/mg, and the biological activities measured by the immature rat ovarian weight method ranged from 7,250 to 7,780 IU/mg. The results of the amino acid compositions of all the hCG-hydatidiform moles were practically identical with those of hCG-normal pregnancies. The carbohydrate moiety of the hCG-hydatidiform mole was also suspected to be almost similar to that of hCG-normal pregnancies by the results of their in vitro and in vivo biological activities. It was demonstrated that hCG-hydatidiform mole was composed of α and β subunits (similar to a hCG-normal pregnancy) when hCG-hydatidiform mole was separated into subunits by SDS disc electrophoresis after treatment with mercaptoethanol. The RIA system of hCG-hydatidiform mole can be established. The concentrations of hCG in sera of normal pregnant women and patients with trophoblastic diseases assayed by hCG-hydatidiform mole RIA were equivalent to those obtained by a standard hCG RIA. Hence, a standard hCG-immunoassay method used in the management of trophoblastic diseases is considered reasonable so far as the immunoantigenecity of hCG is concerned. (author)

Morphological divergence of breeders and helpers in wild Damaraland mole-rat societies.

Science.gov (United States)

Young, Andrew J; Bennett, Nigel C

2010-11-01

The specialization of body shape to an individual's role within society represents a pinnacle of social evolution. Although commonplace among social insects, divergence in the body shapes of breeders and helpers has to date been documented in just one social vertebrate, the naked mole-rat, Heterocephalus glaber; an extraordinary species in which large colony size and frequent inbreeding may have favored the evolution of such specialization. Here, we present new evidence of morphological divergence between breeders and helpers in the Damaraland mole-rat, Fukomys damarensis; a much less socially extreme species that reflects an independent evolutionary origin of sociality. Using longitudinal data from wild populations, we show that dominant female Damaraland mole-rats, like many social insect queens, have a significantly more elongate body shape than subordinates. This difference arises not from a pre-existing difference in the body shapes of subordinates that do, and those that do not, become dominant, but from a modification to the growth trajectory of subordinates on dominance acquisition. Our findings reveal a wider role for morphological divergence within vertebrate societies and, as Damaraland mole-rats neither live in unusually large groups nor inbreed, suggest that circumstances favoring the evolution of such specializations may be more widespread among vertebrates than previously supposed. © 2010 The Author(s). Evolution© 2010 The Society for the Study of Evolution.

A Comparative Analysis of Unit Cohesion in Vietnam

Science.gov (United States)

2014-06-13

winning” the war in Vietnam. One only needs to turn to cinema to see the divide and portrayal of the Vietnam conflict. Movies like, Platoon...disapproved of post-war (World War II) re-colonization, especially the French efforts in Indochina that included Cambodia, Laos and Vietnam. He offered...the political process, and result in a communist government; this became known as the Domino Theory. The United States replaced the French and

CASE STUDY: Vietnam — Information brings progress to Vietnam's ...

International Development Research Centre (IDRC) Digital Library (Canada)

The WUNB is the provincial branch of the Vietnam Women's Union, a unique country-wide ... It also serves to monitor and evaluate their performance. ... Vu Thi Tan explains, detailed information is needed for the union to carry out its work.

Management of pest mole crickets in Florida and Puerto Rico with a nematode and parasitic wasp

International Nuclear Information System (INIS)

Leppla, N.C.; Frank, J.H.; Adjei, M.B.; Vicente, N.E.

2007-01-01

Non-indigenous invasive mole crickets, Scapteriscus vicinus Scudder (Orthoptera: Gryllotalpidae) in Florida and S. didactylus (Latreille) (the 'changa') in Puerto Rico, are being managed with an entomopathogenic nematode, Steinernema scapterisci (Nguyen and Smart) (Rhabditida: Steinernematidae), and a parasitic wasp, Larra bicolor L. (Hymenoptera: Sphecidae). Pest mole cricket populations have declined by 95% in north central Florida since these specialist natural enemies were released and established in the 1980s. Commercial production of the nematode was initiated, nearly 70 billion were applied in 34 Florida counties, and their establishment, spread, and impact on mole crickets were monitored. The infected mole crickets dispersed the nematode rapidly, so that within 6 months these parasites were present in most of the insects trapped in experimental pastures. Three years later, mole cricket populations were reduced to acceptable levels and the bahiagrass had recovered. The nematode was released for the first time in Puerto Rico during 2001 and has persisted; the wasp was introduced in the late 1930s. The geographical distribution of the wasp is being expanded in Florida and Puerto Rico by planting plots of Spermacoce verticillata (L.), a wildflower indigenous to Puerto Rico and widely distributed in southern Florida. Pastures, sod farms, golf courses, landscapes, and vegetable farms in Florida and Puerto Rico are benefiting from biological control of invasive mole crickets. (author) [es

Vietnam; Poverty Reduction Strategy Paper

OpenAIRE

International Monetary Fund

2004-01-01

This paper assesses the Poverty Reduction Strategy Paper of Vietnam, known as the Comprehensive Poverty Reduction and Growth Strategy (CPRGS). It is an action program to achieve economic growth and poverty reduction objectives. This paper reviews the objectives and tasks of socio-economic development and poverty reduction. The government of Vietnam takes poverty reduction as a cutting-through objective in the process of country socio-economic development and declares its commitment to impleme...

Absence of histamine-induced itch in the African naked mole-rat and "rescue" by Substance P.

Science.gov (United States)

Smith, Ewan St John; Blass, Gregory R C; Lewin, Gary R; Park, Thomas J

2010-05-24

Recent research has proposed a pathway in which sensory neurons expressing the capsaicin activated ion channel TRPV1 are required for histamine-induced itch and subsequent scratching behavior. We examined histamine-induced itch in the African naked mole-rat (Heterocephalus glaber) and found that although naked mole-rats display innate scratching behavior, histamine was unable to evoke increased scratching as is observed in most mouse strains. Using calcium imaging, we examined the histamine sensitivity of naked mole-rat dorsal root ganglia (DRG) neurons and identified a population of small diameter neurons activated by histamine, the majority of which are also capsaicin-sensitive. This suggested that naked mole-rat sensory neurons are activated by histamine, but that spinal dorsal horn processing of sensory information is not the same as in other rodents. We have previously shown that naked mole-rats naturally lack substance P (SP) in cutaneous C-fibers, but that the neurokinin-1 receptor is expressed in the superficial spinal cord. This led us to investigate if SP deficiency plays a role in the lack of histamine-induced scratching in this species. After intrathecal administration of SP into the spinal cord we observed robust scratching behavior in response to histamine injection. Our data therefore support a model in which TRPV1-expressing sensory neurons are important for histamine-induced itch. In addition, we demonstrate a requirement for active, SP-induced post-synaptic drive to enable histamine sensitive afferents to drive itch-related behavior in the naked mole-rat. These results illustrate that it is altered dorsal horn connectivity of nociceptors that underlies the lack of itch and pain-related behavior in the naked mole-rat.

Absence of histamine-induced itch in the African naked mole-rat and "rescue" by Substance P

Directory of Open Access Journals (Sweden)

Lewin Gary R

2010-05-01

Full Text Available Abstract Recent research has proposed a pathway in which sensory neurons expressing the capsaicin activated ion channel TRPV1 are required for histamine-induced itch and subsequent scratching behavior. We examined histamine-induced itch in the African naked mole-rat (Heterocephalus glaber and found that although naked mole-rats display innate scratching behavior, histamine was unable to evoke increased scratching as is observed in most mouse strains. Using calcium imaging, we examined the histamine sensitivity of naked mole-rat dorsal root ganglia (DRG neurons and identified a population of small diameter neurons activated by histamine, the majority of which are also capsaicin-sensitive. This suggested that naked mole-rat sensory neurons are activated by histamine, but that spinal dorsal horn processing of sensory information is not the same as in other rodents. We have previously shown that naked mole-rats naturally lack substance P (SP in cutaneous C-fibers, but that the neurokinin-1 receptor is expressed in the superficial spinal cord. This led us to investigate if SP deficiency plays a role in the lack of histamine-induced scratching in this species. After intrathecal administration of SP into the spinal cord we observed robust scratching behavior in response to histamine injection. Our data therefore support a model in which TRPV1-expressing sensory neurons are important for histamine-induced itch. In addition, we demonstrate a requirement for active, SP-induced post-synaptic drive to enable histamine sensitive afferents to drive itch-related behavior in the naked mole-rat. These results illustrate that it is altered dorsal horn connectivity of nociceptors that underlies the lack of itch and pain-related behavior in the naked mole-rat.

Locomotor Activity and Body Temperature Patterns over a Temperature Gradient in the Highveld Mole-Rat (Cryptomys hottentotus pretoriae).

Science.gov (United States)

Haupt, Meghan; Bennett, Nigel C; Oosthuizen, Maria K

2017-01-01

African mole-rats are strictly subterranean mammals that live in extensive burrow systems. High humidity levels in the burrows prevent mole-rats from thermoregulating using evaporative cooling. However, the relatively stable environment of the burrows promotes moderate temperatures and small daily temperature fluctuations. Mole-rats therefore display a relatively wide range of thermoregulation abilities. Some species cannot maintain their body temperatures at a constant level, whereas others employ behavioural thermoregulation. Here we test the effect of ambient temperature on locomotor activity and body temperature, and the relationship between the two parameters, in the highveld mole-rat. We exposed mole-rats to a 12L:12D and a DD light cycle at ambient temperatures of 30°C, 25°C and 20°C while locomotor activity and body temperature were measured simultaneously. In addition, we investigated the endogenous rhythms of locomotor activity and body temperature at different ambient temperatures. Mole-rats displayed nocturnal activity at all three ambient temperatures and were most active at 20°C, but least active at 30°C. Body temperature was highest at 30°C and lowest at 20°C, and the daily cycle was highly correlated with locomotor activity. We show that the mole-rats have endogenous rhythms for both locomotor activity and body temperature. However, the endogenous body temperature rhythm appears to be less robust compared to the locomotor activity rhythm. Female mole-rats appear to be more sensitive to temperature changes than males, increased heterothermy is evident at lower ambient temperatures, whilst males show smaller variation in their body temperatures with changing ambient temperatures. Mole-rats may rely more heavily on behavioural thermoregulation as it is more energy efficient in an already challenging environment.

On nuclear manpower development in Vietnam

International Nuclear Information System (INIS)

Phung Van Duan

2007-01-01

Vietnam began to be interested in education and training on nuclear sciences and related subjects since the early 1960's. A department of Nuclear Physics and Engineering was established in 1970 at the Hanoi University of Technology (HUT), which is the biggest interdisciplinary technological education centre of the country. In Vietnam there are several institutions where exist programmes of education on nuclear sciences and nuclear engineering. But HUT has been being since 1970 the only institution that has underway programme of education on nuclear engineer degree. Although the Department was renamed and its education programme was adjusted, but the objectives of its education programme have been being followed without changes. These objectives are as follows: 1) To develop peaceful applications of atomic energy in Vietnam; 2) To train up engineers on nuclear instrumentation for supporting the first objective; and 3) To prepare initial manpower for introduction of Nuclear Power in Vietnam. Nuclear community of Vietnam is still not so large. Total number of its members increased until 1986, and then decreases up to now. Present average age of members of the community is of 45. In 15 coming years at least 500-700 young people must be educated on programmes on nuclear engineer degree and on nuclear bachelor degree. This is a very difficult task for a developing country such as Vietnam. From a point of view of development, the above-mentioned number is too small, and it must be much more. This makes the task much more difficult. In addition, education on nuclear engineering in the country at present is in a hard situation because of lacking in experienced people, as well as in teaching material and equipment, and, because of weakness of the education programme. So, it may be impossible to achieve success in realization of the task without a large and effective international cooperation in education on nuclear science and engineering. That is why the Asian Network for

Evaluation of the MoleMateTM training program for assessment of suspicious pigmented lesions in primary care

Directory of Open Access Journals (Sweden)

Annabel Wood

2008-05-01

Conclusion The MoleMateTM training program is a potentially effective and acceptable informatics tool to teach practitioners to recognise the features of SPLs identified by the MoleMateTM system. It will be used as part of the intervention in a randomised controlled trial to compare the diagnostic accuracy and appropriate referral rates of practitioners using the MoleMateTM system with best practice in primary care.

The taming of the shrew: batterers' constructions of their wives' narratives.

Science.gov (United States)

Borochowitz, Dalit Yassour

2008-10-01

Constructing a life story is a need shared by all humans to give their lives meaning and coherence. This article explores some of the narrative devices that batterers use to achieve a sense of coherence when telling their stories and justifying their violent behavior. A central theme that emerged from these stories centered on the men's perception of their wives as the embodiment of their own emotions and inner world. Two narrative strategies were identified in this context: (a) The construction of a "couple narrative" that focused on an idealized marital relationship rather than "allowing" the wife her story and (b) constructing a story around the theme of "she's not the same woman I married," which portrays the wife as "a shrew" and the violence as an attempt to discipline her. The stories of 18 batterers were used for this analysis, and two narratives were used to illustrate these strategies.

Vietnam Report 2014

International Development Research Centre (IDRC) Digital Library (Canada)

Vudddn

entrepreneurship and business development, we believe that GEM Vietnam .... indicators have the highest levels: the dynamics of the domestic market ...... either by selling, shutting down or otherwise discontinuing an owner/management.

Social media for non-profit organizations in Vietnam

OpenAIRE

Nguyen, Thy

2016-01-01

The thesis presents about social media in general and social media for non-profit organizations in Vietnam in particular. The writer wanted to explore the disadvantages that non-profits in Vietnam face when using social media and search for recommendations which helps them to use it more efficiently. In the theoretic part, core concepts related to social media were introduced, namely, definition of social media, its types, the popular platforms, situation of social media in Vietnam, pros...

Entry modes of European firms in Vietnam

Directory of Open Access Journals (Sweden)

Daniel Simonet

2012-09-01

Full Text Available Purpose: The purpose of the paper is to explore the entry modes of EU firms setting up operations in Vietnam. Design/methodology/approach: we use a case study approach on Haymarket, Cadbury, Creative Education, Fairchild, Aventis and Artemisinin and Farming International using interviews from managerial professionals in Vietnam. Findings: Despite the fact that Vietnam has been opening up for more than 20 years, licensing is the preferred entry mode because of the risks involved in venturing with local firms; that preference signals a low level commitment and a high perception of risk and state interference. In line with Vietnam transition to state - rather than private market - capitalism, a foreign company opting for a joint-venture will do so with a state-owned rather than privately-owned company. The choice of a subsidiary can be explained by the lack of trust in partners and institutions, not by improvement in the socio-political environment. Limitations: In determining the entry mode strategy, the paper focuses on the Uppsala school’s “psychic distance” (e.g. cultural distance, lack of trust rather than on firm-specific advantages (Rugman, 1980; 2006. Key-words: international entry mode; emerging markets; subsidiary; joint-venture; India; Vietnam

Food Irradiation In Vietnam And Japan

International Nuclear Information System (INIS)

Tamikazy Kume

2011-01-01

In 2008, Japan Atomic Energy Commission of Cabinet Office performed the study of current status of food irradiation in the world. The results showed that the total quantity of irradiated foods in 2005 was 405,000 tons. Seven main countries for food irradiation were China, USA, Ukraine, Brazil, South Africa, Vietnam and Japan. In Japan, only the potato irradiation for sprout inhibition is continued more than 35 years since 1974 but the quantity is decreasing. On the other hand, the food irradiation of Vietnam has been developed rapidly in a short time to export the frozen seafood and fruit. This paper shows the status of food irradiation in Vietnam and Japan, and the progress in both countries after 2005. (author)

High Autophagy in the Naked Mole Rat may Play a Significant Role in Maintaining Good Health

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Shanmin Zhao

2014-02-01

Full Text Available Background/Aims: The maximum lifespan of the naked mole rat is over 28.3 years, which exceeds that of any other rodent species, suggesting that age-related changes in its body composition and functionality are either attenuated or delayed in this extraordinarily long-lived species. However, the mechanisms underlying the aging process in this species are poorly understood. In this study, we investigated whether long-lived naked mole rats display more autophagic activity than short-lived mice. Methods: Hepatic stellate cells isolated from naked mole rats were treated with 50 nM rapamycin or 20 mM 3-methyladenine (3-MA for 12 or 24 h. Expression of the autophagy marker proteins LC3-II and beclin 1 was measured with western blotting and immunohistochemistry. The induction of apoptosis was analyzed by flow cytometry. Results: Our results demonstrate that one-day-old naked mole rats have higher levels of autophagy than one-day-old short-lived C57BL/6 mice, and that both adult naked mole rats (eight months old and adult C57BL/6 mice (eight weeks old have high basal levels of autophagy, which may be an important mechanism inhibiting aging and reducing the risk of age-related diseases. Conclusion: Here, we report that autophagy facilitated the survival of hepatic stellate cells from the naked mole rat, and that treatment with 3-MA or rapamycin increased the ratio of apoptotic cells to normal hepatic stellate cells.

Excited state intramolecular charge transfer reaction in binary mixtures of water and tertiary butanol (TBA): alcohol mole fraction dependence.

Science.gov (United States)

Pradhan, Tuhin; Ghoshal, Piue; Biswas, Ranjit

2008-02-07

The excited state intramolecular charge transfer reaction of 4-(1-azetidinyl)benzonitrile (P4C) has been studied in water-tertiary butanol (TBA) mixtures at different alcohol mole fractions by using steady state and time-resolved fluorescence spectroscopy. The ratio between the areas under the locally excited (LE) and charge transferred (CT) emission bands is found to exhibit a sharp rise at alcohol mole fraction approximately 0.04, a value at which several thermodynamic properties of this mixture is known to show anomalous change due to the enhancement of H-bonding network. The radiative rate associated with the LE emission also shows a maximum at this TBA mole fraction. Although the structural transition from the water-like tetrahedral network to the alcohol-like chain is reflected in the red shift of the absorption spectrum up to TBA mole fraction approximately 0.10, the emission bands (both LE and CT) show the typical nonideal alcohol mole fraction dependence at all TBA mole fractions. Quantum yield, CT radiative rate as well as transition moments also exhibit a nonideal alcohol mole fraction dependence. The time-resolved emission decay of P4C has been found to be biexponential at all TBA mole fractions, regardless of emission collection around either the LE or the CT bands. The time constant associated with the slow component (tau(slow)) shows a minimum at TBA mole fraction approximately 0.04, whereas such a minimum for the fast time constant, tau(fast) (representing the rate of LE --> CT conversion reaction) is not observed. The nonobservation of the minimum in tau(fast) might be due to the limited time resolution employed in our experiments.

Experimental nuclear physics in Vietnam - recent status

International Nuclear Information System (INIS)

Tran Thanh Minh

1995-01-01

Status of research works on experimental nuclear physics in Vietnam is reviewed. Vietnam institutions and main instruments for nuclear research are listed. The results on physics and technology of nuclear reactor, neutron physics, nuclear reactions, radiological safety are mentioned. (N.H.A). 6 tabs, 4 figs

Analysis of internal doses to Mole voles inhabiting the East-Ural radioactive trace

Energy Technology Data Exchange (ETDEWEB)

Malinovsky, G.; Yarmoshenko, I. [Institute of Industrial Ecology UB RAS (Russian Federation); Chibiryak, M.; Vasil' ev, A. [Institute of Plant and Animal Ecology UB RAS (Russian Federation)

2014-07-01

Substantial task of development of approaches to radiation protection of non-human biota is investigation of relationships of exposure to dose, and dose to effects. Small mammals inhabiting territory of the East-Ural Radioactive Trace (EURT) are affected to ionizing radiation for many generations after accident at Mayak plutonium production in 1957. According to results of numerous studies a number of effects of exposure are observed. It is remarkable that the revealed effects are both negative and adaptive. In particular, the analysis of the variability of morphological structures of the axial skull and lower jaw in the population of northern mole vole (Ellobius talpinus Pall.), the burrowing rodent inhabiting the EURT, is of great interest. At the same time there is no reliable assessment of the radiation doses to these animals. Earlier we developed the approach to assess internal doses to mouse-like rodents (mice and voles) caused by incorporated {sup 90}Sr, which is the main dose contributing radionuclide at the EURT. Dose assessments are based on the results of beta-radiometry of intact bone. Routine methods for measuring the activity concentration of {sup 90}Sr in skeleton require ashing of samples, however in morphometric studies the destruction of material should be avoided: the skulls of mole voles are stored in the environmental samples depository of IPAE. Coefficients linking results of beta-radiometry of intact bone and activity concentration of {sup 90}Sr in skull of mouse was obtained basing on comparison of results of beta-radiometry of intact bone and bone ash. Obtained coefficients cannot be directly applied for calculating activity concentration of {sup 90}Sr in mole vole skulls because they are significantly larger. Therefore the additional study is required to assess proper coefficient of conversion from beta-radiometry to activity concentration of {sup 90}Sr. Developed dose assessment procedure includes application of the published values of

Solar radiation during rewarming from torpor in elephant shrews: supplementation or substitution of endogenous heat production?

Science.gov (United States)

Thompson, Michelle L; Mzilikazi, Nomakwezi; Bennett, Nigel C; McKechnie, Andrew E

2015-01-01

Many small mammals bask in the sun during rewarming from heterothermy, but the implications of this behaviour for their energy balance remain little understood. Specifically, it remains unclear whether solar radiation supplements endogenous metabolic thermogenesis (i.e., rewarming occurs through the additive effects of internally-produced and external heat), or whether solar radiation reduces the energy required to rewarm by substituting (i.e, replacing) metabolic heat production. To address this question, we examined patterns of torpor and rewarming rates in eastern rock elephant shrews (Elephantulus myurus) housed in outdoor cages with access to either natural levels of solar radiation or levels that were experimentally reduced by means of shade cloth. We also tested whether acclimation to solar radiation availability was manifested via phenotypic flexibility in basal metabolic rate (BMR), non-shivering thermogenesis (NST) capacity and/or summit metabolism (Msum). Rewarming rates varied significantly among treatments, with elephant shrews experiencing natural solar radiation levels rewarming faster than conspecifics experiencing solar radiation levels equivalent to approximately 20% or 40% of natural levels. BMR differed significantly between individuals experiencing natural levels of solar radiation and conspecifics experiencing approximately 20% of natural levels, but no between-treatment difference was evident for NST capacity or Msum. The positive relationship between solar radiation availability and rewarming rate, together with the absence of acclimation in maximum non-shivering and total heat production capacities, suggests that under the conditions of this study solar radiation supplemented rather than substituted metabolic thermogenesis as a source of heat during rewarming from heterothermy.

Livestock grazing intensity affects abundance of Common shrews (Sorex araneus) in two meadows in Denmark

DEFF Research Database (Denmark)

Schmidt, Niels Martin; Olsen, Henrik; Leirs, Herwig

2009-01-01

habitat type for a large number of animal species in today's fragmented and intensively cultivated landscape of Europe. Here we focus on the population characteristics of Common shrews Sorex araneus in relation to livestock grazing intensity in two wet meadows in western Denmark. Results: High grazing...... as well as in most other European countries, the amount of land covered by semi-natural grassland has decreased dramatically during the 20th century concurrent with the general intensification of the agricultural production. To reverse this trend, actions are being taken in many places to either maintain...

[Life cycle of Maupasina weissi Seurat, 1913, Subuluroidea Nematode, parasite of the elephant shrew (author's transl)].

Science.gov (United States)

Quentin, J C; Verdier, J M

1979-01-01

The life cycle of Maupasina weissi Seurat, 1913, the parasite of the elephant shrew, has been experimentally obtained from the intermediate host Locusta migratoria. The biology of this Nematoda is considered as being more primitive than the Subuluridae: -- egg maturation in external environment is in fact necessary to the Maupasina larvae to penetrate into the insect, -- The different localizations of the infective larvae, such as mesenteron regeneration crypta, fat body, demonstrate that the parasite is not completely adaptated to its intermediate host, -- the ontogenesis of cephalic structures is characterized by an hypertrophy of the archaic structures mainly from cuticular origin.

Stress Resistance in the Naked Mole-Rat: The Bare Essentials – A Mini-Review

Science.gov (United States)

Lewis, Kaitlyn N.; Mele, James; Hornsby, Peter J.; Buffenstein, Rochelle

2012-01-01

Background Studies comparing similar-sized species with disparate longevity may elucidate novel mechanisms that abrogate aging and prolong good health. We focus on the longest living rodent, the naked mole-rat. This mouse-sized mammal lives ∼8 times longer than do mice and, despite high levels of oxidative damage evident at a young age, it is not only very resistant to spontaneous neoplasia but also shows minimal decline in age-associated physiological traits. Objectives We assess the current status of stress resistance and longevity, focusing in particular on the molecular and cellular responses to cytotoxins and other stressors between the short-lived laboratory mouse and the naked mole-rat. Results Like other experimental animal models of lifespan extension, naked mole-rat fibroblasts are extremely tolerant of a broad spectrum of cytotoxins including heat, heavy metals, DNA-damaging agents and xenobiotics, showing LD50 values between 2- and 20-fold greater than those of fibroblasts of shorter-lived mice. Our new data reveal that naked mole-rat fibroblasts stop proliferating even at low doses of toxin whereas those mouse fibroblasts that survive treatment rapidly re-enter the cell cycle and may proliferate with DNA damage. Naked mole-rat fibroblasts also show significantly higher constitutive levels of both p53 and Nrf2 protein levels and activity, and this increases even further in response to toxins. Conclusion Enhanced cell signaling via p53 and Nrf2 protects cells against proliferating with damage, augments clearance of damaged proteins and organelles and facilitates the maintenance of both genomic and protein integrity. These pathways collectively regulate a myriad of mechanisms which may contribute to the attenuated aging profile and sustained healthspan of the naked mole-rat. Understanding how these are regulated may be also integral to sustaining positive human healthspan well into old age and may elucidate novel therapeutics for delaying the onset and

Radioimmunoassay of β sub unit HCG following hydatidiform mole or chorionic carcinoma

International Nuclear Information System (INIS)

Tscherne, G.; Puerstner, P.

1979-01-01

The radioimmunoassay of Beta Sub Unit HCG in the serum heralds a marked improvement in the diagnosis of gestational trophoblastic disease. In nine cases of hydatidiform mole and three cases of chorionic carcinoma serial examinations of the Beta Sub Unit HCG were performed. When the immunologic pregnancy test became negative following a hydatidiform mole or following treatment of chorionic carcinoma, the HCG excretion remained above detectable values for several more weeks. The decrease of Beta Sub Unit serum HCG was either linear or in fluctuations. The detection of fluctuations or a secondary rise in the Beta Sub Unit HCG titre permits the early diagnosis of invasive trophoblastic disease following hydatidiform mole or of insufficient treatment or recurrence in cases of chorionic carcinoma. Our results suggest that the optimal follow-up with Beta Sub Unit serum HCG is by weekly determinations until four consecutive determinations remained negative. This is followed by two determinations at bi-weekly intervals and thereafter monthly follow-up examinations. (orig.) 891 AJ/orig. 892 BRE [de

Prevalence and Factors Associated with Hydatidiform Mole among Patients Undergoing Uterine Evacuation at Mbarara Regional Referral Hospital

Directory of Open Access Journals (Sweden)

Olivier Mulisya

2018-01-01

Full Text Available Objective. We sought to determine the prevalence of and factors associated with hydatidiform molar gestations amongst patients undergoing uterine evacuation at Mbarara Regional Referral Hospital (MRRH, Mbarara, Uganda. Methods. This was a cross-sectional study carried out from November 2016 to February 2017. All patients admitted for uterine evacuation for nonviable pregnancy were included. The study registered 181 patients. Data were collected on sociodemographics, medical conditions, obstetrics, and gynecological factors. The evacuated tissue received a full gross and histopathologic examination. Cases of pathologically suspected complete hydatidiform mole were confirmed by p57 immunohistochemistry. Data were analyzed using STATA 13. Results. The prevalence of hydatidiform mole was 6.1% (11/181. All detected moles were complete hydatidiform moles, and there were no diagnosed partial hydatidiform moles. Clinical diagnosis of molar pregnancy was suspected in 13 patients, but only 69.2% (9/13 were confirmed as molar pregnancies histologically. Two cases were clinically unsuspected. Factors that had a significant relationship with complete hydatidiform mole included maternal age of 35 years and above (aOR 13.5; CI: 1.46–125.31; p=0.00, gestational age beyond the first trimester at the time of uterine evacuation (aOR 6.2; CI: 1.07–36.14; p=0.04, and history of previous abortion (aOR 4.3; CI: 1.00–18.57; p=0.05. Conclusion. The prevalence of complete hydatidiform mole was high at 6.1%. Associated risk factors included advanced maternal age (35 years and above, history of previous abortions, and gestational age beyond the first trimester at the time of evacuations. Recommendations. We recommend putting in place capacity to do routine histopathological examination of all products of conception especially those at high risk for a molar gestation either by clinical suspicion or by risk factors including advanced maternal age, advanced gestational

Vietnam military service history and prostate cancer

Directory of Open Access Journals (Sweden)

Fritschi Lin

2006-03-01

Full Text Available Abstract Background Three decades after US and Australian forces withdrew from Vietnam, there has been much public interest in the health consequences of service in Vietnam. One controversial question is whether the risk of prostate cancer amongst Vietnam veterans is increased. This paper examines relationships between military history, family history and risk of prostate cancer in a population-based case control study. Methods Cases were selected from the Cancer Registry of Western Australia as incident cases of histologically-confirmed prostate cancer, and controls were age-matched and selected from the Western Australian electoral roll. Study participants were asked to report any military service history and details about that service. Results Between January 2001 and September 2002, 606 cases and 471 controls aged between 40–75 years were recruited. An increased prostate cancer risk was observed in men reporting they were deployed in Vietnam although this was not statistically significant (OR = 2.12; 95% CI 0.88–5.06. An increased risk was also observed in men reporting prostate cancer in fathers (OR = 1.90; 95% CI 1.20–3.00 or brothers (OR = 2.05; 95% CI 1.20–3.50 diagnosed with prostate cancer. Conclusion These findings support a positive association between prostate cancer and military service history in the Vietnam war and a first degree relative family history of prostate cancer.

31 CFR 500.565 - Family remittances to nationals of Vietnam and Cambodia.

Science.gov (United States)

2010-07-01

... Vietnam and Cambodia. 500.565 Section 500.565 Money and Finance: Treasury Regulations Relating to Money... remittances to nationals of Vietnam and Cambodia. (a) The remittances specified in this section are authorized... relative is a national of Vietnam or Cambodia, is a resident of Vietnam, Cambodia, or a country to which...

Teaching the Vietnam War: A Sociological Approach.

Science.gov (United States)

Starr, Jerold M.

1995-01-01

Maintains that, because of its importance in modern U.S. history, over 300 college courses are taught on the Vietnam War. Asserts that studying the war helps students develop critical thinking skills needed for citizenship. Describes the texts, formats, and assignments used in a college sociology course on the Vietnam War. (CFR)

Naked mole-rat mortality rates defy Gompertzian laws by not increasing with age

Science.gov (United States)

Ruby, J Graham; Smith, Megan

2018-01-01

The longest-lived rodent, the naked mole-rat (Heterocephalus glaber), has a reported maximum lifespan of >30 years and exhibits delayed and/or attenuated age-associated physiological declines. We questioned whether these mouse-sized, eusocial rodents conform to Gompertzian mortality laws by experiencing an exponentially increasing risk of death as they get older. We compiled and analyzed a large compendium of historical naked mole-rat lifespan data with >3000 data points. Kaplan-Meier analyses revealed a substantial portion of the population to have survived at 30 years of age. Moreover, unlike all other mammals studied to date, and regardless of sex or breeding-status, the age-specific hazard of mortality did not increase with age, even at ages 25-fold past their time to reproductive maturity. This absence of hazard increase with age, in defiance of Gompertz’s law, uniquely identifies the naked mole-rat as a non-aging mammal, confirming its status as an exceptional model for biogerontology. PMID:29364116

Sex, social status, and CRF receptor densities in naked mole-rats.

Science.gov (United States)

Beery, Annaliese K; Bicks, Lucy; Mooney, Skyler J; Goodwin, Nastacia L; Holmes, Melissa M

2016-02-01

Naked mole-rats (Heterocephalus glaber) live in groups that are notable for their large size and caste structure, with breeding monopolized by a single female and a small number of males. Recent studies have demonstrated substantial differences between the brains of breeders and subordinates induced by changes in social standing. Corticotropin-releasing factor (CRF) receptors-which bind the hormone CRF as well as related peptides-are important regulators of stress and anxiety, and are emerging as factors affecting social behavior. We conducted autoradiographic analyses of CRF1 and CRF2 receptor binding densities in female and male naked mole-rats varying in breeding status. Both globally and in specific brain regions, CRF1 receptor densities varied with breeding status. CRF1 receptor densities were higher in subordinates across brain regions, and particularly in the piriform cortex and cortical amygdala. Sex differences were present in CRF2 receptor binding densities, as is the case in multiple vole species. CRF2 receptor densities were higher in females, both globally and in the cortical amygdala and lateral amygdalar nucleus. These results provide novel insights into the neurobiology of social hierarchy in naked mole-rats, and add to a growing body of work that links changes in the CRF system with social behavior. © 2015 Wiley Periodicals, Inc.

Photic induction of Fos in the suprachiasmatic nucleus of African mole-rats: responses to increasing irradiance.

Science.gov (United States)

Oosthuizen, Maria K; Bennett, Nigel C; Cooper, Howard M

2010-09-01

African mole-rats (family Bathyergidae) are strictly subterranean rodent species that are rarely exposed to environmental light. Morphological and physiological adaptations to the underground environment include a severely reduced eye size and regressed visual system. Responses of the circadian system to light, however, appear to be intact, since mole-rats are able to entrain their circadian activity rhythms to the light-dark cycle and light induces Fos expression in the suprachiasmatic nucleus (SCN). Social organization varies from solitary species to highly elaborated eusocial structures, characterized by a distinct division of labor and in which one reproductive female regulates the behavior and reproductive physiology of other individuals in the colony. The authors studied light-induced Fos expression in the SCN to increasing light intensities in four mole-rat species, ranging from strictly solitary to highly social. In the solitary Cape mole-rat, light induces significant Fos expression in the SCN, and the number of Fos-immunopositive cells increases with increasing light intensity. In contrast, Fos induction in the SCN of social species was slightly greater than, but not statistically different from, the dark-control animals as is typical of most rodents. One species showed a trend for an increase in expression with increased light, whereas a second species showed no trend in expression. In the naked mole-rat, Fos expression appeared higher in the dark-controls than in the animals exposed to light, although the differences in Fos expression were not significant. These results suggest a gradient in the sensitivity of the circadian system to light in mole-rats, with a higher percentage of individuals that are unresponsive to light in correlation with the degree of sociality. In highly social species, such as the naked mole-rat that live in a relatively stable subterranean milieu in terms of food availability, temperature, constant darkness, and devoid of 24-h

Plasticity and constraints on social evolution in African mole-rats: ultimate and proximate factors.

Science.gov (United States)

Faulkes, Chris G; Bennett, Nigel C

2013-05-19

Here, we review comparative studies of African mole-rats (family Bathyergidae) to explain how constraints acting at the ultimate (environmental) and proximate (organismal) levels have led to convergent gains and losses of sociality within this extensive adaptive radiation of subterranean rodents endemic to sub-Saharan Africa. At the ultimate level, living in environments that range from mesic through to arid has led to both variation and flexibility in social organization among species, culminating in the pinnacle of social evolution in the eusocial naked and Damaraland mole-rats (Heterocephalus glaber and Fukomys damarensis). The common mole-rat (Cryptomys hottentotus) provides a model example of how plasticity in social traits exists within a single species inhabiting areas with different ecological constraint. At the proximate level, reproductive strategies and cooperative breeding may be constrained by the correlated evolution of a suite of traits including physiological suppression of reproduction, the development of physiological and morphological castes, and the mode of ovulatory control and seasonality in breeding. Furthermore, recent neurobiological advances indicate that differential patterns of neurotransmitter expression within the forebrain may underpin (and limit) either a solitary or group living/cooperative lifestyle not only in mole-rats, but also more widely among disparate mammalian taxa.

Hardness evaluation of cured urea-formaldehyde resins with different formaldehyde/urea mole ratios using nanoindentation method

Science.gov (United States)

Byung-Dae Park; Charles R. Frihart; Yan Yu; Adya P. Singh

2013-01-01

To understand the influence of formaldehyde/urea (F/U) mole ratio on the properties of urea–formaldehyde (UF) resins, this study investigated hardness of cured UF resins with different F/U mole ratios using a nanoindentation method. The traditional Brinell hardness (HB) method was also used...

Health economics of screening for hypertension in Vietnam

NARCIS (Netherlands)

Nguyen, Thi Phuong Lan

2016-01-01

The studies aims to identify the burden of a cardiovascular diseases and solutions to manage it in Vietnam, notably hypertension screening. The studies confirmed that hypertension creates a great burden in Vietnam in terms of cardiovascular diseases, from economic, clinical and social perspectives.

Elevated sister chromatid exchange frequencies in New Zealand Vietnam War veterans.

Science.gov (United States)

Rowland, R E; Edwards, L A; Podd, J V

2007-01-01

From July 1965 until November 1971, New Zealand Defence Force Personnel fought in the Vietnam War. During this time more than 76,500,000 litres of phenoxylic herbicides were sprayed over parts of Southern Vietnam and Laos, the most common being known as 'Agent Orange'. The current study aimed to ascertain whether or not New Zealand Vietnam War veterans show evidence of genetic disturbance arising as a consequence of their now confirmed exposure to these defoliants. A sample group of 24 New Zealand Vietnam War veterans and 23 control volunteers were compared using an SCE (sister chromatid exchange) analysis. The results from the SCE study show a highly significant difference (P Vietnam War veterans studied here were exposed to a clastogenic substance(s) which continues to exert an observable genetic effect today, and suggest that this is attributable to their service in Vietnam. Copyright 2007 S. Karger AG, Basel.

Definition of the mole (IUPAC Recommendation 2017)

OpenAIRE

Marquardt, Roberto; Meija, Juris; Mester, Zoltán; Towns, Marcy; Weir, Ron; Davis, Richard; Stohner, Jürgen

2018-01-01

In 2011 the General Conference on Weights and Measures (CGPM) noted the intention of the International Committee for Weights and Measures (CIPM) to revise the entire International System of Units (SI) by linking all seven base units to seven fundamental physical constants. Of particular interest to chemists, new definitions for the kilogram and the mole have been proposed. A recent IUPAC Technical Report discussed these new definitions in relation to immediate consequences for the chemical co...

Efficacy of NETDC (New England Trophoblastic Disease Center prognostic index score to predict gestational trophoblastic tumor from hydatidiform mole

Directory of Open Access Journals (Sweden)

Khrismawan Khrismawan

2004-03-01

Full Text Available A prospective longitudinal analytic study assessing the efficacy of NETDC (New England Trophoblastic Disease Center prognostic index score in predicting malignancy after hydatidiform mole had been performed. Of the parameter evaluated; age of patients, type of hydatidiform mole, uterine enlargement, serum hCG level, lutein cyst, and presence of complicating factors were significant risk factors for malignancy after hydatidiform mole were evacuated (p<0.032. The study were done on 50 women diagnosed with hydatidiform mole with 1 year observation (January 2001-December 2002 at the Department of Obstetrics and Gynecology, Mohammad Hoesin Hospital, Palembang. The results showed that the NETDC prognostic index score predicted malignancy in 50% of high risk group and 10% in low risk group (p<0.05. This showed a higher number than that found by the WHO (19%-30%. The risk for incidence of  malignancy after hydatidiform mole in the high risk group is 9.0 times higher compared to that of the low risk group (CI: 1.769-45.786. (Med J Indones 2004; 13: 40-6 Keywords: New England Trophoblastic Disease Center (NETDC, gestational trophoblastic tumor, hydatidiform mole, high and low risk

The Naked Mole Rat Genome Resource : facilitating analyses of cancer and longevity-related adaptations

OpenAIRE

Keane, Michael; Craig, Thomas; Alfoldi, Jessica; Berlin, Aaron M; Johnson, Jeremy; Seluanov, Andrei; Gorbunova, Vera; Di Palma, Federica; Lindblad-Toh, Kerstin; Church, George M; de Magalhaes, Joao Pedro

2014-01-01

MOTIVATION: The naked mole rat (Heterocephalus glaber) is an exceptionally long-lived and cancer-resistant rodent native to East Africa. Although its genome was previously sequenced, here we report a new assembly sequenced by us with substantially higher N50 values for scaffolds and contigs. RESULTS: We analyzed the annotation of this new improved assembly and identified candidate genomic adaptations which may have contributed to the evolution of the naked mole rat's extraordinary traits, inc...

The Asian house shrew Suncus murinus as a reservoir and source of human outbreaks of plague in Madagascar.

Science.gov (United States)

Rahelinirina, Soanandrasana; Rajerison, Minoarisoa; Telfer, Sandra; Savin, Cyril; Carniel, Elisabeth; Duplantier, Jean-Marc

2017-11-01

Identifying key reservoirs for zoonoses is crucial for understanding variation in incidence. Plague re-emerged in Mahajanga, Madagascar in the 1990s but there has been no confirmed case since 1999. Here we combine ecological and genetic data, from during and after the epidemics, with experimental infections to examine the role of the shrew Suncus murinus in the plague epidemiological cycle. The predominance of S. murinus captures during the epidemics, their carriage of the flea vector and their infection with Yersinia pestis suggest they played an important role in the maintenance and transmission of plague. S. murinus exhibit a high but variable resistance to experimental Y. pestis infections, providing evidence of its ability to act as a maintenance host. Genetic analyses of the strains isolated from various hosts were consistent with two partially-linked transmission cycles, with plague persisting within the S. murinus population, occasionally spilling over into the rat and human populations. The recent isolation from a rat in Mahajanga of a Y. pestis strain genetically close to shrew strains obtained during the epidemics reinforces this hypothesis and suggests circulation of plague continues. The observed decline in S. murinus and Xenopsylla cheopis since the epidemics appears to have decreased the frequency of spillover events to the more susceptible rats, which act as a source of infection for humans. Although this may explain the lack of confirmed human cases in recent years, the current circulation of plague within the city highlights the continuing health threat.

Current transport mechanism in graphene/AlGaN/GaN heterostructures with various Al mole fractions

Science.gov (United States)

Pandit, Bhishma; Seo, Tae Hoon; Ryu, Beo Deul; Cho, Jaehee

2016-06-01

The current transport mechanism of graphene formed on AlxGa1-xN/GaN heterostructures with various Al mole fractions (x = 0.15, 0.20, 0.30, and 0.40) is investigated. The current-voltage measurement from graphene to AlGaN/GaN shows an excellent rectifying property. The extracted Schottky barrier height of the graphene/AlGaN/GaN contacts increases with the Al mole fraction in AlGaN. However, the current transport mechanism deviates from the Schottky-Mott theory owing to the deterioration of AlGaN crystal quality at high Al mole fractions confirmed by reverse leakage current measurement.

Current transport mechanism in graphene/AlGaN/GaN heterostructures with various Al mole fractions

Directory of Open Access Journals (Sweden)

Bhishma Pandit

2016-06-01

Full Text Available The current transport mechanism of graphene formed on AlxGa1−xN/GaN heterostructures with various Al mole fractions (x = 0.15, 0.20, 0.30, and 0.40 is investigated. The current–voltage measurement from graphene to AlGaN/GaN shows an excellent rectifying property. The extracted Schottky barrier height of the graphene/AlGaN/GaN contacts increases with the Al mole fraction in AlGaN. However, the current transport mechanism deviates from the Schottky-Mott theory owing to the deterioration of AlGaN crystal quality at high Al mole fractions confirmed by reverse leakage current measurement.

A project for the strengthening of cooperative relations between Korea and Vietnam

International Nuclear Information System (INIS)

Yang, M. H.; Kim, H. S.; Chung, W. S.; Kim, H. J.; Yun, S. W.; Ko, H. S.; Nho, I. Y.

2002-03-01

This study was carried out in order to review the cooperation with Vietnam and strengthening of cooperative relations with Vietnam. During the study, the current status and prospect of electricity, use and development of nuclear energy in vietnam, were investigated including nuclear power plant and cooperative relations between two nations were also established. It was agreed through exchanges of visits of cooperation delegation; 1) exchange of visits of cooperation delegation, 2) holding of policy seminar for high level decision makers of Vietnam 3) cooperaton between MOST/MOSTE, 4) joint feasibility study for the construction of KSNP into Vietnam and technical presentation of KSNP. It is recommended that cooperaion with Vietnam be implemented systematically through the long term based basic directions and integrated national strategies

Investigating the environmental Kuznets curve hypothesis in Vietnam

International Nuclear Information System (INIS)

Al-Mulali, Usama; Saboori, Behnaz; Ozturk, Ilhan

2015-01-01

This study investigates the existence of the environmental Kuznets curve (EKC) hypothesis in Vietnam during the period 1981–2011. To realize the goals of this study, a pollution model was established applying the Autoregressive Distributed Lag (ARDL) methodology. The results revealed that the pollution haven hypothesis does exist in Vietnam because capital increases pollution. In addition, imports also increase pollution which indicates that most of Vietnam's imported products are energy intensive and highly polluted. However, exports have no effect on pollution which indicates that the level of exports is not significant enough to affect pollution. Moreover, fossil fuel energy consumption increases pollution while renewable energy consumption has no significant effect in reducing pollution. Furthermore, labor force reduces pollution since most of Vietnam's labor force is in the agricultural and services sectors which are less energy intensive than the industrial sector. Based on the obtained results, the EKC hypothesis does not exist because the relationship between GDP and pollution is positive in both the short and long run. - Highlights: • The environmental Kuznets curve (EKC) hypothesis in Vietnam is investigated. • The Autoregressive Distributed Lag (ARDL) methodology was utilized. • The EKC hypothesis does not exist

Sister Lab Program Prospective Partner Nuclear Profile: Vietnam

International Nuclear Information System (INIS)

Bissani, M; Tyson, S

2006-01-01

Vietnam's nuclear program began in the 1960s with the installation at Dalat of a 250 kW TRIGA Mk-II research reactor under the U.S. Atoms for Peace Program. The reactor was shut down and its core removed only a few years later, and the nuclear research program was suspended until after the end of the civil war in the late 1970s. The Soviet Union assisted Vietnam in restoring the Dalat reactor to an operational status in 1984, trained a cadre of scientific and technical staff in its operation, and contributed to the development of nuclear science for the medical and agricultural sectors. In the agricultural area in particular, Vietnamese experts have been very successful in developing mutant strains of rice, and continue to work with the IAEA to yield strains that have a shorter growing period, increased resistance to disease, and other desirable characteristics. Rice has always been the main crop in Vietnam, but technical cooperation with the IAEA and other states has enabled the country to become one of the top rice producers in the world, exporting much of its annual crop to over two dozen countries annually. More recently, Vietnam's government has shown increasing interest in developing a civil nuclear program to supplement its fossil fuel and other energy resources. Projections from a variety of open sources, ranging from the IAEA, the U.S. Department of Energy's Energy Information Administration (EIA), the Vietnamese government, energy corporations, and think tanks all predict a massive increase in energy consumption--especially electricity--within Vietnam and the region as a whole. This growth in consumption will require a corresponding increase in energy production, which in Vietnam is currently satisfied mainly by fossil fuels (coal) and renewable energy (hydropower and biomass); Vietnam has a refining capacity of about 800 barrels/day. Most of its crude oil is exported to generate export income, and is not used to generate electricity. Although Vietnam is

Strategy in the Vietnam War: Western Concepts, Eastern Conflict and the Roots of Failure.

Science.gov (United States)

Weland, James

1990-01-01

Critiques U.S. military assumptions concerning the war in Vietnam. Discusses the North Vietnamese strategic approach to gaining control of South Vietnam. Traces the history of the Vietnam War, analyzing specific U.S. military operations in Vietnam and reasons for their failure. Contends that U.S. strategic ethnocentrism lead to defeat in Vietnam.…

EVALUATION OF THE TRADE RELATIONSHIP BETWEEN VIETNAM AND CHINA; VIETNAM AND UNITED STATES: A COMPARISON USING GRAVITY MODEL

Directory of Open Access Journals (Sweden)

Lien Thi Dinh

2017-06-01

Full Text Available This study aims to evaluate the determinants of trade relationship between two largest trading partners of Vietnam, United States and China. Using gravity model for time series data from 1986 to 2015, the study found that economic growth rate plays a crucial role in stimulating the trade flow. Both trade relationships fit with the practical approach of Heckscher-Ohlin theory, stating that trade flow increases between countries with different income levels. The most important finding of this study lines on the results regarding the impact of trade agreements. While United States-Vietnam bilateral agreement creates trade, the trade agreement between ASEAN and China produced trade diversion. As China expands its markets among ASEAN countries, Vietnam should diversify its export markets to improve its export flow.

Vietnam Report No. 2382

National Research Council Canada - National Science Library

1982-01-01

.... This document contains articles on Vietnam. Some topics discussed are military affairs and public security, international relations, trade, aid, economic planning, trade and finance, agriculture, heavy industry, construction, transportation...

Factors influencing business of mobile telecommunication service providers in Vietnam

Directory of Open Access Journals (Sweden)

Ha Thanh Hai

2018-05-01

Full Text Available According to the Ministry of Information and Communications in Vietnam, as of November 2015, the number of mobile subscribers is over 120 million ones, accounting for over 86% of the total number of telephone subscribers. With a total population of over 92 million Vietnam citizens, a stable national economy and a large populations of young consumers in the country, mobile communication industries still have a huge potentials for future development. Telecommunication service providers in Vietnam are facing fierce competition. Subscribers are expecting OTT (Over the Top applications, good quality service and handset subsidy. This study investigated whether legal frameworks, OTT applications, quality of service and handset subsidy are important components of mobile telecommunication service in Vietnam. This study used quantitative method to distribute surveys to mobile subscribers. Findings found that all four factors significantly influence mobile business in Vietnam. Thus, telecommunication service providers in Vietnam must continuously innovate to enhance operational competitiveness, improve business efficiency, expand business scale, and improve its position in the market in order to ensure sustainable development. Moreover, Vietnamese government needs to develop a legal framework to help mobile telecommunication service providers enhance the common interests and benefits of the entire society.

Wicked problems: a value chain approach from Vietnam's dairy product.

Science.gov (United States)

Khoi, Nguyen Viet

2013-12-01

In the past few years, dairy industry has become one of the fastest growing sectors in the packaged food industry of Vietnam. However, the value-added creation among different activities in the value chain of Vietnam dairy sector is distributed unequally. In the production activities, the dairy farmers gain low value-added rate due to high input cost. Whereas the processing activities, which managed by big companies, generates high profitability and Vietnamese consumers seem to have few choices due to the lack of dairy companies in the market. These wicked problems caused an unsustainable development to the dairy value chain of Vietnam. This paper, therefore, will map and analyze the value chain of the dairy industry in Vietnam. It will also assess the value created in each activity in order to imply solutions for a sustainable development of Vietnam's dairy industry. M10, M11.

The Vietnam War

DEFF Research Database (Denmark)

Godbolt, James; Larsen, Chris Holmsted; Rasmussen, Søren Hein

2009-01-01

This article investigates the role of the Vietnam War in Danish and Norwegian politics. We argue that Danish and Norwegian membership in NATO and an unstable parliamentary situation may explain why these countries, unlike Sweden, did not take on the lead in the international protest against the war....... Non-socialistic coalitions came to power in Norway and Denmark in the latter half of the 1960s which to an extent explains why the social democratic parties in both countries became more critical of the US. By the end of the 1960s, foreign policy as well as public attitudes towards the war converged...... in Denmark, Sweden and Norway, and in all three countries powerful protest movements emerged that were remarkably similar. The Vietnam War strengthened the left in general and promoted a leftist politics of solidarity that influenced Swedish, Danish and Norwegian foreign policy-making of the 1970s....

Improving quality of foreign direct investment attraction in Vietnam

OpenAIRE

Ngo Phuc Hanh; Đao Van Hùng; Nguyen Thac Hoat; Dao Thi Thu Trang

2017-01-01

Foreign direct investment (FDI) enterprises are playing a key role in Vietnam's economy. By the end of 2016, there are more than 21,398 FDI projects in force, with the total registered capital of nearly 293 billion USD. One hundred six countries and territories have invested in 19 industries in 68 provinces and cities of Vietnam. These investments have added a large amount of capital to the economy, which has basically been used effectively, contributing to the economic growth of Vietnam. In ...

The Economic Impact of Land Use Rights in Rural Vietnam

Science.gov (United States)

2013-11-01

Rental Markets In Transition: Evidence From Rural Vietnam." Oxford Bulletin Of Economics And Statistics 70, no. 1: 67- 101. ECONIS, EBSCOhost ...Rental Markets In Transition: Evidence From Rural Vietnam." Oxford Bulletin Of Economics And Statistics 70, no. 1: 67- 101. ECONIS, EBSCOhost ...generating revenue through taxation in a previously non-existent real estate market . Before 1993, Vietnam experienced a long period of land reform

Vietnam Report No. 2415

National Research Council Canada - National Science Library

1982-01-01

.... This report contains articles about Vietnam. Some topics include military affairs and public security, international relations, party activities and government, economic planning, trade and finance, agriculture, heavy industry and construction...

Census in North Vietnam

National Research Council Canada - National Science Library

1960-01-01

This population census decree aims at collecting the most fundamental and accurate data on the population situation of North Vietnam to lay the foundation for all plans and public administration policies...

Solar energy and rural development in Vietnam

International Nuclear Information System (INIS)

Anon.

1999-01-01

Photovoltaic systems have already been present in Vietnam for numerous years. Since 1994 the projects intensified with the launch of the Energy-Solidarity-Vietnam program which has just been concluded in 1999. This paper deals with the different stages of this project: choice of photovoltaic power, the partners engagement, obstacles overcome and the help of the electricity for the economic development. (A.L.B.)

Membrane phospholipid composition may contribute to exceptional longevity of the naked mole-rat (Heterocephalus glaber): a comparative study using shotgun lipidomics.

Science.gov (United States)

Mitchell, Todd W; Buffenstein, Rochelle; Hulbert, A J

2007-11-01

Phospholipids containing highly polyunsaturated fatty acids are particularly prone to peroxidation and membrane composition may therefore influence longevity. Phospholipid molecules, in particular those containing docosahexaenoic acid (DHA), from the skeletal muscle, heart, liver and liver mitochondria were identified and quantified using mass-spectrometry shotgun lipidomics in two similar-sized rodents that show an approximately 9-fold difference in maximum lifespan. The naked mole rat is the longest-living rodent known with a maximum lifespan of >28 years. Total phospholipid distribution is similar in tissues of both species; DHA is only found in phosphatidylcholines (PC), phosphatidylethanolamines (PE) and phosphatidylserines (PS), and DHA is relatively more concentrated in PE than PC. Naked mole-rats have fewer molecular species of both PC and PE than do mice. DHA-containing phospholipids represent 27-57% of all phospholipids in mice but only 2-6% in naked mole-rats. Furthermore, while mice have small amounts of di-polyunsaturated PC and PE, these are lacking in naked mole-rats. Vinyl ether-linked phospholipids (plasmalogens) are higher in naked mole-rat tissues than in mice. The lower level of DHA-containing phospholipids suggests a lower susceptibility to peroxidative damage in membranes of naked mole-rats compared to mice. Whereas the high level of plasmalogens might enhance membrane antioxidant protection in naked mole-rats compared to mice. Both characteristics possibly contribute to the exceptional longevity of naked mole-rats and may indicate a special role for peroxisomes in this extended longevity.

A dynamic approach to assess international competitiveness of Vietnam's garment and textile industry.

Science.gov (United States)

Vu, Huong Thanh; Pham, Lam Cat

2016-01-01

Garment and textile (G&T) industry has been playing as a driving force for the socio-economic development of Vietnam. With the international integration process and rising challenges from the global market, there is a need to examine international competitiveness of Vietnam's G&T industry to find out what Vietnam should focus on to enhance its position in the global market place. This paper, by using the Generalized Double Diamond Model (GDDM), analyzed international competitiveness of Vietnam's G&T industry and compared it with China. The results showed that Vietnam was less competitive than China in all four attributes of the GDDM. The lowest competitiveness of Vietnam in comparison with China was Related and Supporting industries, followed by Factor Conditions. Therefore, the paper argued that although Vietnam should improve all of the four attributes in the long term, Vietnam must put a high priority on developing Related and Supporting Industries and then enhance Factor Conditions while maintaining its strengths over China in terms of G&T export growths and favorable business context.

Four Cases of Spontaneous Neoplasia in the Naked Mole-Rat (Heterocephalus glaber), A Putative Cancer-Resistant Species.

Science.gov (United States)

Taylor, Kyle R; Milone, Nicholas A; Rodriguez, Carlos E

2017-01-01

The naked mole-rat (Heterocephalus glaber) is widely acclaimed to be cancer-resistant and of considerable research interest based on a paucity of reports of neoplasia in this species. We have, however, encountered four spontaneous cases of neoplasia and one presumptive case of neoplasia through routine necropsy and biopsy of individuals in a zoo collection of nonhybrid naked mole-rats bred from a single pair. One case each of metastasizing hepatocellular carcinoma, nephroblastoma (Wilms' tumor), and multicentric lymphosarcoma, as well as presumptive esophageal adenocarcinoma (Barrett's esophagus-like) was identified postmortem among 37 nonautolyzed necropsy submissions of naked mole-rats over 1-year-old that were submitted for necropsy between 1998 and August 2015. One incidental case of cutaneous hemangioma was also identified antemortem by skin biopsy from one naked mole-rat examined for trauma. © The Author 2016. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Spermatozoa of the shrew, Suncus murinus, undergo the acrosome reaction and then selectively kill cells in penetrating the cumulus oophorus.

Science.gov (United States)

Kaneko, T; Iida, H; Bedford, J M; Mōri, T

2001-08-01

In the musk shrew, Suncus murinus (and other shrews), the cumulus oophorus is ovulated as a discrete, compact, matrix-free ball of cells linked by specialized junctions. In examining how they penetrate the cumulus, Suncus spermatozoa were observed to first bind consistently by the ventral face over the acrosomal region to the exposed smooth surface of a peripheral cumulus cell. This was apparently followed by point fusions between the plasma and outer acrosomal membranes. Thereafter, spermatozoa without acrosomes were observed within cumulus cells that displayed signs of necrosis, as did some radially neighboring cumulus cells linked by zona adherens and gap junctions. Eventually, penetration of spermatozoa as far as the perizonal space around the zona pellucida left linear tracks of locally necrotic cells flanked by normal cumulus cells. Based on these and previous observations, we conclude that the acrosome reaction in Suncus is always induced by cumulus cells, and that reacted spermatozoa penetrate the cumulus by selective invasion and killing of cumulus cells along a linear track. Loss of the acrosome also exposes an apical body/perforatorium that is covered with barbs that appear to assist reacted fertilizing spermatozoa in binding to the zona pellucida. Because fertilized eggs displayed no other spermatozoa within or bound to the zona, an efficient block to polyspermy must prevent such binding of additional spermatozoa.

The Independence of Vietnam Regulatory Body

International Nuclear Information System (INIS)

Nguyen, Hoang Anh; Choi, Kwang Sik

2011-01-01

In the field of peaceful purposes, the activity of nuclear agencies is often divided into 2 systems: the nuclear application system and the safety system. Depending on the magnitude of atomic energy application development, the responsibility of the safety system was assigned to a few agencies in each country. In Vietnam, the nuclear safety responsibility is assigned primarily to the radiation and nuclear safety agency. However, the provisions of the normative system of law prevailing in other sectors such as investment, construction, electricity or environmental protection, many agencies are responsible for ensuring safety in each sector, leading to a conflict of interest among those agencies. This is the weakness in the management system of Vietnam compared to other countries with nuclear power development. The purpose of this paper is to analyze the state of Vietnam's legal framework in nuclear safety regulation and its dependence of regulatory body aspects and promoting the way to overcome it

Universal service in Vietnam: An institutional approach

DEFF Research Database (Denmark)

Do Manh, Thai; Falch, Morten

2018-01-01

Applying institutional theory to look at the Program 74 (a universal service policy) in Vietnam, this paper concludes that the Vietnamese universal service policy was strongly affected by formal institutional factors (the international agreements and the directives of the Communist Party of Vietnam...... - CPV), in which the international agreements played a leading role and the CPV’s directives played a guarantee role. The formulation and implementation of the universal service policy in Vietnam were mainly concentrated on action at levels 2 and 3 (formal and informal institutional arrangement......, and formal institutional environment). The paper recommends that nations favouring a top-down approach not based on a market-oriented regime should deregulate and emphasize the role of provincial governments as well as encourage private sectors/social organizations and rural users to be more involved...

Suicide of Australians during the Vietnam War.

Science.gov (United States)

Pridmore, Saxby; Ahmadi, Jamshid; Pridmore, William

2018-04-01

National suicide rates fall during times of war. This fits with the notion of the population coming together against a common foe. But, what happens in the case of a war which is not fully supported, which draws the population and families apart? We consider this question by examining the Australian suicide rates during the divisive Vietnam War. We graphed and examined the Australian suicide figures for 1921-2010. We found clear evidence of a decrease in the suicide rate for World War II (consistent with other studies), but a marked elevation of suicide during the Vietnam War. The elevation of the Australian suicide rate during the Vietnam War is consistent with Durkheim's social integration model - when social integration is lessened, either by individual characteristics or societal characteristics, the risk of suicide rises.

IDRC in Vietnam

International Development Research Centre (IDRC) Digital Library (Canada)

credible links to policymakers and development practitioners. VERN research findings appear in the coun- try's Human Development Report and its results informed trade policy, includ- ing preparation for Vietnam's accession to the World Trade Organization. Better use of resources. IDRC support since the early 1990s has.

Formation of Skål International Club in Vietnam

OpenAIRE

Tran, Quang

2014-01-01

This paper presents a project plan of Skål International Vietnam as a new joining club, with the purpose of forming a new Skål International club in Vietnam. The idea was born in September, 2011 during the 72nd Skål International World Congress in Turku, Finland, where the author – a Young Skål had invited to attend . Vietnam situated in the peninsula of South-East Asia, the country holds great potentials of nature, culture and human power for tourism growth. In spite of joining an Inter...

[Identification of a novel WART-like chromosome rearrangement in complex heterozygotes in an interracial hybrid zone of the common shrew Sorex araneus L].

Science.gov (United States)

Pavlova, S V; Bulatova, N Sh

2010-09-01

Karyotypes uncharacteristic of pure races or hybrids were identified in the interracial hybrid zones of the common shrew Sorex araneus L. that were recently discovered in the European part of Russia. This suggests the actual existence in natural populations of WART-like rearrangements (whole-arm reciprocal translocations) along with Robertsonian fusions of acrocentrics. Demonstration of new and still rare chromosome variants is the aim of this communication.

Indium mole fraction effect on the structural and optical properties of quaternary AlInGaN epilayers

International Nuclear Information System (INIS)

Liu, J P; Jin, R Q; Zhang, J C; Wang, J F; Wu, M; Zhu, J J; Zhao, D G; Wang, Y T; Yang, H

2004-01-01

AlInGaN quaternary epilayers with varying In mole fraction were investigated using triple-axis x-ray diffraction and photoluminescence measurements. The indium compositional fluctuation is enhanced with increasing In mole fraction, whereas the mosaicity of the AlInGaN epilayers is determined through the GaN template quality. Based on the analysis of the temperature dependence of the PL peak position, it is found that the localization effect strengthens with increasing In mole fraction due to the larger fluctuations of the In distribution. Increasing the influence of the localized state results in increasing the emission intensity and FWHM with the In content

Experimental Investigation of InSight HP3 Mole Interaction with Martian Regolith Simulant. Quasi-Static and Dynamic Penetration Testing

Science.gov (United States)

Marshall, Jason P.; Hudson, Troy L.; Andrade, José E.

2017-10-01

The InSight mission launches in 2018 to characterize several geophysical quantities on Mars, including the heat flow from the planetary interior. This quantity will be calculated by utilizing measurements of the thermal conductivity and the thermal gradient down to 5 meters below the Martian surface. One of the components of InSight is the Mole, which hammers into the Martian regolith to facilitate these thermal property measurements. In this paper, we experimentally investigated the effect of the Mole's penetrating action on regolith compaction and mechanical properties. Quasi-static and dynamic experiments were run with a 2D model of the 3D cylindrical mole. Force resistance data was captured with load cells. Deformation information was captured in images and analyzed using Digitial Image Correlation (DIC). Additionally, we used existing approximations of Martian regolith thermal conductivity to estimate the change in the surrounding granular material's thermal conductivity due to the Mole's penetration. We found that the Mole has the potential to cause a high degree of densification, especially if the initial granular material is relatively loose. The effect on the thermal conductivity from this densification was found to be relatively small in first-order calculations though more complete thermal models incorporating this densification should be a subject of further investigation. The results obtained provide an initial estimate of the Mole's impact on Martian regolith thermal properties.

Investigation of the presence and antinociceptive function of muscarinic acetylcholine receptors in the African naked mole-rat (Heterocephalus glaber).

Science.gov (United States)

Jørgensen, Kristine B; Krogh-Jensen, Karen; Pickering, Darryl S; Kanui, Titus I; Abelson, Klas S P

2016-01-01

The present study investigated the cholinergic system in the African naked mole-rat (Heterocephalus glaber) with focus on the muscarinic acetylcholine receptor subtypes M1 and M4. The protein sequences for the subtypes m 1-5 of the naked mole-rat were compared to that of the house mouse (Mus musculus) using basic local alignment search tool (BLAST). The presence and function of M1 and M4 was investigated in vivo, using the formalin test with the muscarinic receptor agonists xanomeline and VU0152100. Spinal cord tissue from the naked mole-rat was used for receptor saturation binding studies with [(3)H]-N-methylscopolamine. The BLAST test revealed 95 % protein sequence homology showing the naked mole-rat to have the genetic potential to express all five muscarinic acetylcholine receptor subtypes. A significant reduction in pain behavior was demonstrated after administration of 8.4 mg/kg in the formalin test. Administration of 50 mg/kg VU0152100 resulted in a non-significant tendency towards antinociception. The antinociceptive effects were reversed by the muscarinic acetylcholine receptor antagonist atropine. Binding studies indicated presence of muscarinic acetylcholine receptors with a radioligand affinity comparable to that reported in mice. In conclusion, muscarinic acetylcholine receptor subtypes are present in the naked mole-rat and contribute to antinociception in the naked mole-rat.

The Asian house shrew Suncus murinus as a reservoir and source of human outbreaks of plague in Madagascar.

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Soanandrasana Rahelinirina

2017-11-01

Full Text Available Identifying key reservoirs for zoonoses is crucial for understanding variation in incidence. Plague re-emerged in Mahajanga, Madagascar in the 1990s but there has been no confirmed case since 1999. Here we combine ecological and genetic data, from during and after the epidemics, with experimental infections to examine the role of the shrew Suncus murinus in the plague epidemiological cycle. The predominance of S. murinus captures during the epidemics, their carriage of the flea vector and their infection with Yersinia pestis suggest they played an important role in the maintenance and transmission of plague. S. murinus exhibit a high but variable resistance to experimental Y. pestis infections, providing evidence of its ability to act as a maintenance host. Genetic analyses of the strains isolated from various hosts were consistent with two partially-linked transmission cycles, with plague persisting within the S. murinus population, occasionally spilling over into the rat and human populations. The recent isolation from a rat in Mahajanga of a Y. pestis strain genetically close to shrew strains obtained during the epidemics reinforces this hypothesis and suggests circulation of plague continues. The observed decline in S. murinus and Xenopsylla cheopis since the epidemics appears to have decreased the frequency of spillover events to the more susceptible rats, which act as a source of infection for humans. Although this may explain the lack of confirmed human cases in recent years, the current circulation of plague within the city highlights the continuing health threat.

The impact of fire on habitat use by the short-snouted elephant shrew ('Elephantulus brachyrhynchus') in North West Province, South Africa

OpenAIRE

Yarnell, R; Metcalfe, D; Dunstone, N; Burnside, N; Scott, D

2008-01-01

Several studies have investigated the response of small mammal populations to fire, but few have investigated behavioural responses to habitat modification. In this study we investigated the impact of fire on home range, habitat use and activity patterns of the short-snouted elephant shrew (Elephantulus brachyrhynchus) by radio-tracking individuals before and after a fire event. All animals survived the passage of fire in termite mound refugia. Before the fire, grassland was used more than th...

Making History Come Alive with the Nonfiction Literature of the Vietnam War.

Science.gov (United States)

Johannessen, Larry R.

2003-01-01

Considers student response to nonfiction Vietnam War literature and discusses why students should study Vietnam War nonfiction. Presents strategies for teaching nonfiction Vietnam War literature. Presents follow-up research and writing activities that are designed to enable students to connect reading, writing, and thinking. Concludes that the…

Suspended futures : the Vietnamization of South Vietnamese history and memory

OpenAIRE

Bui, Long Thanh

2011-01-01

In 1969, President Richard Nixon announced the "Vietnamization" of the Vietnam War, a handover of responsibility for winning the war from the U.S. to its allies, the South Vietnamese. Vietnamization articulated the challenges of achieving political freedom and historical agency for South Vietnamese people. Conceptualizing this term in the early 21st century, I seek to address the ways the war (and its subjects) is called into the present to speak about the representability and addressability ...

Health issues in nursing in Vietnam.

Science.gov (United States)

Kristy, S J

1995-01-01

Major health concerns are not currently addressed in Vietnam as the country strives to upgrade its economic status. The current standard of medical care is rudimentary at best, as is the education and practice of Vietnamese nurses. The Ministry of Health in Vietnam has directed the Medical College of Hanoi to commence a 4-year degree in nursing in 1994. Historical, practical, political, economic, social, and cultural issues affect the development of nursing as a profession. Assistance from the West is sought by the Medical College in Hanoi.

Women at war: The crucible of Vietnam

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Anica Pless Kaiser

2017-12-01

Short-term (20 years; 12% and civilian women (13%. Additional differences regarding warzone experiences, homecoming support, and health outcomes were found among groups. All military and civilian women who served in Vietnam were less likely to have married or have had children than women from the general population, χ2 (8 = 643.72, p < .001. Career military women were happier than women in the general population (48% were “very happy”, as compared to 38%. Civilian women who served in Vietnam reported better health than women in the other groups. Regression analyses indicated that long-term physical health was mainly influenced by demographic characteristics, and that mental health and PTSD symptoms were influenced by warzone and homecoming experiences. Overall, this paper provides insight into the experiences of the understudied women who served in Vietnam, and sheds light on subgroup differences within the sample.

Trade potential of climate smart goods of Vietnam: An application of gravity model

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Trung Van Vu

2016-01-01

Full Text Available This paper examines the trade potential of climate smart goods (CSG of Vietnam. In particular, the study employs gravity model with panel data for bilateral trade between Vietnam and its 45 partners from 2002 to 2013 with an objective of identifying the determinants explaining Vietnam's trade of climate smart products. The estimation results reveal that economic size, market size, distance, real exchange rate, border, and the quality of infrastructure of both Vietnam and its trading partners play a major role in bilateral trade of CSG. Additionally, the paper applies the method using speed of convergence and the estimated gravity equation to answer whether Vietnam has fully realized the potential trade of CSG. Accordingly, Vietnam has strong opportunity for trade expansion with 19 out of 45 countries in the scope of this paper.

‘Misure‘ e ‘Flyting’: il linguaggio dell'inversione in The Taming of the Shrew di William Shakespeare

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Bianca Del Villano

2016-11-01

Rilevante, in questo senso, è una delle prime commedie di Shakespeare, The Taming of the Shrew, in cui il tropo dell’inversione si articola attraverso l’originale elaborazione di una ‘inversione dell’inversione’, un device drammaturgico che reinterpreta il Misrule della tradizione, attraverso: 1 espedienti metateatrali; 2 fusione tra linguaggio cortese e scortese presentando esempi dell'antica pratica del flyting; 3 la problematizzazione dei ruoli sociali e di genere. La comunicazione che propongo analizza brevemente le forme del popolaresco in Inghilterra per soffermarsi con maggiore attenzione sul teatro shakespeariano e in particolare su La bisbetica domata.

Genetic signatures for enhanced olfaction in the African mole-rats.

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Sofia Stathopoulos

Full Text Available The Olfactory Receptor (OR superfamily, the largest in the vertebrate genome, is responsible for vertebrate olfaction and is traditionally subdivided into 17 OR families. Recent studies characterising whole-OR subgenomes revealed a 'birth and death' model of evolution for a range of species, however little is known about fine-scale evolutionary dynamics within single-OR families. This study reports the first assessment of fine-scale OR evolution and variation in African mole-rats (Bathyergidae, a family of subterranean rodents endemic to sub-Saharan Africa. Because of the selective pressures of life underground, enhanced olfaction is proposed to be fundamental to the evolutionary success of the Bathyergidae, resulting in a highly diversified OR gene-repertoire. Using a PCR-sequencing approach, we analysed variation in the OR7 family across 14 extant bathyergid species, which revealed enhanced levels of functional polymorphisms concentrated across the receptors' ligand-binding region. We propose that mole-rats are able to recognise a broad range of odorants and that this diversity is reflected throughout their OR7 gene repertoire. Using both classic tests and tree-based methods to test for signals of selection, we investigate evolutionary forces across the mole-rat OR7 gene tree. Four well-supported clades emerged in the OR phylogeny, with varying signals of selection; from neutrality to positive and purifying selection. Bathyergid life-history traits and environmental niche-specialisation are explored as possible drivers of adaptive OR evolution, emerging as non-exclusive contributors to the positive selection observed at OR7 genes. Our results reveal unexpected complexity of evolutionary mechanisms acting within a single OR family, providing insightful perspectives into OR evolutionary dynamics.

Multidimensional MRI-CT atlas of the naked mole-rat brain

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Fumiko eSeki

2013-12-01

Full Text Available Naked mole-rats have a variety of distinctive features such as the organisation of a hierarchical society (known as eusociality, extraordinary longevity, and cancer resistance; thus, it would be worthwhile investigating these animals in detail. One important task is the preparation of a brain atlas database that provide comprehensive information containing multidimensional data with various image contrasts, which can be achievable using a magnetic resonance imaging (MRI. Advanced MRI techniques such as diffusion tensor imaging (DTI, which generates high contrast images of fibre structures, can characterise unique morphological properties in addition to conventional MRI. To obtain high spatial resolution images, MR histology, DTI, and X-ray computed tomography (CT were performed on the fixed adult brain. Skull and brain structures were segmented as well as reconstructed in stereotaxic coordinates. Data were also acquired for the neonatal brain to allow developmental changes to be observed. Moreover, in vivo imaging of naked mole-rats was established as an evaluation tool of live animals. The data obtained comprised three-dimensional (3D images with high tissue contrast as well as stereotaxic coordinates. Developmental differences in the visual system were highlighted in particular by DTI. Although it was difficult to delineate optic nerves in the mature adult brain, parts of them could be distinguished in the immature neonatal brain. From observation of cortical thickness, possibility of high somatosensory system development replaced to the visual system was indicated. 3D visualisation of brain structures in the atlas as well as the establishment of in vivo imaging would promote neuroimaging researches towards detection of novel characteristics of eusocial naked mole-rats.

Factors in Early Adolescence Associated With a Mole-Prone Phenotype in Late Adolescence.

Science.gov (United States)

Xu, Haoming; Marchetti, Michael A; Dusza, Stephen W; Chung, Esther; Fonseca, Maira; Scope, Alon; Geller, Alan C; Bishop, Marilyn; Marghoob, Ashfaq A; Halpern, Allan C

2017-10-01

Nevi are important phenotypic risk factors for melanoma in adults. Few studies have examined the constitutional and behavioral factors associated with a mole-prone phenotype in adolescents. To identify host, behavioral, and dermoscopic factors in early adolescence (age, 14 years) that are associated with a mole-prone phenotype in late adolescence (age, 17 years). A prospective observational cohort study from the Study of Nevi in Children was conducted from January 1, 2009, to December 31, 2014, with a 2- to 3-year follow-up. A total of 569 students from the school system in Framingham, Massachusetts, were enrolled in the 8th or 9th grade (baseline; mean [SD] age, 14.4 [0.7] years). The overall retention rate was 73.3%, and 417 students were reassessed in the 11th grade. Mole-prone phenotype in the 11th grade, defined as total nevus count of the back and 1 randomly selected leg in the top decile of the cohort or having any nevi greater than 5 mm in diameter. Of the 417 students assessed at follow-up in the 11th grade (166 females and 251 males; mean [SD] age, 17.0 [0.4] years), 111 participants (26.6%) demonstrated a mole-prone phenotype: 69 students (62.2%) with 1 nevus greater than 5 mm in diameter, 23 students (20.7%) with total nevus count in the top decile, and 19 students (17.1%) with both characteristics. On multivariate analysis, baseline total nevus count (adjusted odds ratio, 9.08; 95% CI, 4.0-23.7; P adolescents for higher-intensity counseling about sun protection and skin self-examination.

Tranio Transformed: Social Anxieties and Social Metamorphosis in The Taming of the Shrew

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Sonya L. Brockman

2015-03-01

Full Text Available The article discusses Elizabethan anxieties about the increasing fluidity of social status through an examination of the servant Tranio in Shakespeare’s The Taming of the Shrew. It argues that Tranio’s informed and willing participation in this social performance embodies the anxieties about social mobility held by members of the Elizabethan elite. In contrast to other figures of social metamorphosis in the play, Tranio’s social transformation is temporary, even though, like Christopher Sly, he is transformed into a gentleman at the behest of his Lord. He must return to his servile status in the final act, however, not only because he can so successfully perform the role of master, but because he knowingly participates in his own social metamorphosis. The article suggests, in conclusion, that it is the servant’s knowledge of his own performative power that makes him a threat in Elizabethan society. 

Women’s education in Vietnam and the changes of socio-economic environment. Comparative thoughts based on cases from Vietnam and Denmark

DEFF Research Database (Denmark)

Nørlund, Irene

2012-01-01

Tendensen til at kvinder i stigende grad vinder ind på mænd i uddannelsessystemet og har overhalet dem på selv de høejeste niveauer i forhold til antal i Danmark er ikke uden parelleller i Vietnam. Kvinderne i Vietnam er ikke så ligestillede i Danmark, men der er sket store forbedringer inden for...

High School Education in Vietnam

OpenAIRE

Hasebe, Io

2018-01-01

In this report, I will introduce high school school education in Vietnam in two aspects: time schedule and language instruction. When I had an international exchange with local high school students, I was surprised at how fluently students spoke English and Japanese and thus became interested in language instruction in Vietnam. As I continued my research, I discovered many unique differences between Vietnam and Japan in terms of education. This is why I chose high school education as my repor...

Decarbonization scenarios in the electricity sector in Vietnam

International Nuclear Information System (INIS)

Dang, Van Thanh

2016-01-01

Reduction of CO_2 emissions issue is clearly a world challenge today and COP21 highlighted the international requirements for countries to address related issues in the short and long term. The fundamental objective of the thesis is to contribute to the identification of possible climate policy solutions related to growing electricity production in a developing country, namely Vietnam, taking into account the need to reduce carbon energy sources. For this purpose several scenarios for electricity sector development are constructed in order to measure effects of choices related to the electricity production on CO_2 emissions. The thesis presents an overview of the energy situation in Vietnam and highlights the rapid increase in electricity consumption due to population pressure and new needs. It also considers major issues of coal and gas imports, new energy sources, in light of economic constraints but also environmental challenges. The theoretical and analytical chapter reviews the analyses of electricity master plans construction, major available economic tools for energy demand forecast models. This forms the framework to understanding the complexity of the 'electric bet' which Vietnam faces. After a presentation of potential quantitative simulation instruments, ELECsim was chosen for modeling the electricity sector in Vietnam. This leads to a comprehensive scenario approach; Scenarios are based on several assumptions about the evolution of economic growth and demographics, energy prices, the power generation technology development, the declared carbon value, discount rates and change rate. As a first step in energy and climate policy Vietnam can control the demand growth by strong action on energy efficiency, while reducing parallel to both the electricity production costs and CO_2 emissions. Several scenarios are then proposed, highlighting both the need to search for higher energy efficiency and the promotion of low-carbon energies. Research envisages a rapid

Twin pregnancy with both complete hydatiform mole and coexistent alive fetus: Case report

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Achour Radhouane

2015-12-01

Full Text Available Twin pregnancy consisting of a complete hydatidiform mole coexisting with a live fetus is a rare condition with an incidence of 1 in 22000 to 1 in 100000 pregnancies. Clinical information is limited and management is difficult due to the risk of pregnancy complications such as fetal death, vaginal bleeding, preeclampsia, hyperthyroidism, and the risk of persistent gestational trophoblastic disease. Thus, the report described about the change of size and implantation site of the molar mass coexisting with a live fetus is rare especially about sonographic findings such as echo patterns. Recently we experienced a case of complete hydatidiform mole with a healthy infant delivered at term.

State governance of pesticide use and trade in Vietnam

NARCIS (Netherlands)

Pham Van Hoi,; Mol, A.P.J.; Oosterveer, P.J.M.

2013-01-01

Vietnam is facing serious challenges with respect to the amount and toxicity of the pesticides used. With hardly any domestic pesticides production, Vietnam experienced an exponential growth of both the quantity and the value of imported pesticides in recent years. And the increasing import of newly

RNA sequencing reveals differential expression of mitochondrial and oxidation reduction genes in the long-lived naked mole-rat when compared to mice.

Science.gov (United States)

Yu, Chuanfei; Li, Yang; Holmes, Andrew; Szafranski, Karol; Faulkes, Chris G; Coen, Clive W; Buffenstein, Rochelle; Platzer, Matthias; de Magalhães, João Pedro; Church, George M

2011-01-01

The naked mole-rat (Heterocephalus glaber) is a long-lived, cancer resistant rodent and there is a great interest in identifying the adaptations responsible for these and other of its unique traits. We employed RNA sequencing to compare liver gene expression profiles between naked mole-rats and wild-derived mice. Our results indicate that genes associated with oxidoreduction and mitochondria were expressed at higher relative levels in naked mole-rats. The largest effect is nearly 300-fold higher expression of epithelial cell adhesion molecule (Epcam), a tumour-associated protein. Also of interest are the protease inhibitor, alpha2-macroglobulin (A2m), and the mitochondrial complex II subunit Sdhc, both ageing-related genes found strongly over-expressed in the naked mole-rat. These results hint at possible candidates for specifying species differences in ageing and cancer, and in particular suggest complex alterations in mitochondrial and oxidation reduction pathways in the naked mole-rat. Our differential gene expression analysis obviated the need for a reference naked mole-rat genome by employing a combination of Illumina/Solexa and 454 platforms for transcriptome sequencing and assembling transcriptome contigs of the non-sequenced species. Overall, our work provides new research foci and methods for studying the naked mole-rat's fascinating characteristics.

RNA sequencing reveals differential expression of mitochondrial and oxidation reduction genes in the long-lived naked mole-rat when compared to mice.

Directory of Open Access Journals (Sweden)

Chuanfei Yu

Full Text Available The naked mole-rat (Heterocephalus glaber is a long-lived, cancer resistant rodent and there is a great interest in identifying the adaptations responsible for these and other of its unique traits. We employed RNA sequencing to compare liver gene expression profiles between naked mole-rats and wild-derived mice. Our results indicate that genes associated with oxidoreduction and mitochondria were expressed at higher relative levels in naked mole-rats. The largest effect is nearly 300-fold higher expression of epithelial cell adhesion molecule (Epcam, a tumour-associated protein. Also of interest are the protease inhibitor, alpha2-macroglobulin (A2m, and the mitochondrial complex II subunit Sdhc, both ageing-related genes found strongly over-expressed in the naked mole-rat. These results hint at possible candidates for specifying species differences in ageing and cancer, and in particular suggest complex alterations in mitochondrial and oxidation reduction pathways in the naked mole-rat. Our differential gene expression analysis obviated the need for a reference naked mole-rat genome by employing a combination of Illumina/Solexa and 454 platforms for transcriptome sequencing and assembling transcriptome contigs of the non-sequenced species. Overall, our work provides new research foci and methods for studying the naked mole-rat's fascinating characteristics.

The insoluble question of electric power in Vietnam

International Nuclear Information System (INIS)

Mottet, Eric; Lasserre, Frederic

2016-01-01

An economic dragon for the last twenty years or so, Vietnam is faced with a strongly growing demand for electric energy. Though the country is rich of many different resources necessary to producing electricity, most of them are available in limited quantities. According to forecasts for the 2030-2050 period, Vietnam's coal and natural gas resources will not be able to meet the national demand. Consequently, Hanoi's main goals are to develop and invest in hydroelectricity, renewable energies and a civil nuclear programme. For lack of rigorous planning, adequate financing and given the tensions in the South China Sea, Vietnam's electric energy production growth plan seems technically, financially and geo-politically unfeasible without the help of foreign actors, ultimately weakening the Party-State

Taxonomic Notes on the Genus Delta de Saussure (Hymenoptera: Vespidae: Eumeninae from Vietnam

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Nguyen, Lien Thi Phuong

2015-02-01

Full Text Available A taxonomic study of the genus Delta de Saussure, 1855 from Vietnam is presented. A total of four species are recorded: D. campaniforme campaniforme (Fabricius, 1775, D. conoideum (Gmelin, 1790, D. esuriens esuriens (Fabricius, 1787, and D. pyriforme pyriforme (Fabricius, 1775. Of these, D. campaniforme campaniforme was first recorded from Vietnam by de Saussure et al., 1904, under the name Eumenes esuriens and is now reconfirmed to occur in Vietnam after more than 100 years, and D. conoideum is newly recorded from Vietnam. A key to species based on morphological characters is given with illustrations, and distributional records in Vietnam are also provided.

Stratification and the Emergence of the Postsecondary Private Education Sector in Vietnam

Science.gov (United States)

Goyette, Kimberly Ann

2012-01-01

Vietnam has a strong public postsecondary education sector that has only recently begun to experience growth in nonpublic institutions. I investigate how the growth of nonpublic institutions may be related to stratification in Vietnam. I find that these institutions are more likely to serve more advantaged students from South Vietnam. Students pay…

Expression patterns of ERVWE1/Syncytin-1 and other placentally expressed human endogenous retroviruses along the malignant transformation process of hydatidiform moles.

Science.gov (United States)

Bolze, Pierre-Adrien; Patrier, Sophie; Cheynet, Valérie; Oriol, Guy; Massardier, Jérôme; Hajri, Touria; Guillotte, Michèle; Bossus, Marc; Sanlaville, Damien; Golfier, François; Mallet, François

2016-03-01

Up to 20% of hydatidiform moles are followed by malignant transformation in gestational trophoblastic neoplasia and require chemotherapy. Syncytin-1 is involved in human placental morphogenesis and is also expressed in various cancers. We assessed the predictive value of the expression of Syncytin-1 and its interactants in the malignant transformation process of hydatidiform moles. Syncytin-1 glycoprotein was localized by immunohistochemistry in hydatidiform moles, gestational trophoblastic neoplasia and control placentas. The transcription levels of its locus ERVWE1, its interaction partners (hASCT1, hASCT2, TLR4 and DC-SIGN) and two loci (ERVFRDE1 and ERV3) involved the expression of other placental envelopes were assessed by real-time PCR. Syncytin-1 glycoprotein was expressed in syncytiotrophoblast of hydatidiform moles with an apical enhancement when compared with normal placentas. Moles with further malignant transformation had a higher staining intensity of Syncytin-1 surface unit C-terminus but the transcription level of its locus ERVWE1 was not different from that of moles with further remission and normal placentas. hASCT1 and TLR4, showed lower transcription levels in complete moles when compared to normal placentas. ERVWE1, ERVFRDE1 and ERV3 transcription was down-regulated in hydatidiform moles and gestational trophoblastic neoplasia. Variations of Syncytin-1 protein localization and down-regulation of hASCT1 and TLR4 transcription are likely to reflect altered functions of Syncytin-1 in the premalignant context of complete moles. The reduced transcription in gestational trophoblastic diseases of ERVWE1, ERVFRDE1 and ERV3, which expression during normal pregnancy is differentially regulated by promoter region methylation, suggest a joint dysregulation mechanism in malignant context. Copyright © 2016 Elsevier Ltd. All rights reserved.

Migration and persistence of human influenza A viruses, Vietnam, 2001-2008.

Science.gov (United States)

Le, Mai Quynh; Lam, Ha Minh; Cuong, Vuong Duc; Lam, Tommy Tsan-Yuk; Halpin, Rebecca A; Wentworth, David E; Hien, Nguyen Tran; Thanh, Le Thi; Phuong, Hoang Vu Mai; Horby, Peter; Boni, Maciej F

2013-11-01

Understanding global influenza migration and persistence is crucial for vaccine strain selection. Using 240 new human influenza A virus whole genomes collected in Vietnam during 2001-2008, we looked for persistence patterns and migratory connections between Vietnam and other countries. We found that viruses in Vietnam migrate to and from China, Hong Kong, Taiwan, Cambodia, Japan, South Korea, and the United States. We attempted to reduce geographic bias by generating phylogenies subsampled at the year and country levels. However, migration events in these phylogenies were still driven by the presence or absence of sequence data, indicating that an epidemiologic study design that controls for prevalence is required for robust migration analysis. With whole-genome data, most migration events are not detectable from the phylogeny of the hemagglutinin segment alone, although general migratory relationships between Vietnam and other countries are visible in the hemagglutinin phylogeny. It is possible that virus lineages in Vietnam persisted for >1 year.

Bone Marrow Mesenchymal Stem-Cell Transplantation Promotes Functional Improvement Associated with CNTF-STAT3 Activation after Hemi-Sectioned Spinal Cord Injury in Tree Shrews

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Liu-Lin Xiong

2017-06-01

Full Text Available Hemi-sectioned spinal cord injury (hSCI can lead to spastic paralysis on the injured side, as well as flaccid paralysis on the contralateral side, which can negatively affect a patient’s daily life. Stem-cell therapy may offer an effective treatment option for individuals with hSCI. To examine the role of bone marrow mesenchymal stem cells (BMSCs transplantation on hSCI and explore related mechanisms in the tree shrews, here, we created a model of hSCI by inducing injury at the tenth thoracic vertebra (T10. Hoechst 33342-labeled BMSCs derived from adult tree shrews were isolated, cultured, and implanted into the spinal cord around the injury site at 9 days after injury. The isolated BMSCs were able to survive, proliferate and release a variety of neurotrophic factors (NTFs both in vitro and in vivo. At 28 days after injury, compared with the sham group, the hSCI group displayed scar formation and dramatic elevations in the mean interleukin 1 beta (IL-1β density and cell apoptosis level, whereas the expression of signal transducer and activator of transcription 3 (STAT3 and ciliary neurotrophic factor (CNTF mRNA was reduced. Following BMSC transplantation, motoneurons extent of shrinkage were reduced and the animals’ Basso, Beattie, and Bresnahan (BBB locomotion scale scores were significantly higher at 21 and 28 days after injury when compared with the injured group. Moreover, the hSCI-induced elevations in scar formation, IL-1β, and cell apoptosis were reduced by BMSC transplantation to levels that were close to those of the sham group. Corresponding elevations in the expression of STAT3 and CNTF mRNA were observed in the hSCI + BMSCs group, and the levels were not significantly different from those observed in the sham group. Together, our results support that grafted BMSCs can significantly improve locomotor function in tree shrews subjected to hSCI and that this improvement is associated with the upregulation of CNTF and STAT3

Adult naked mole-rat brain retains the NMDA receptor subunit GluN2D associated with hypoxia tolerance in neonatal mammals.

Science.gov (United States)

Peterson, Bethany L; Park, Thomas J; Larson, John

2012-01-11

Adult naked mole-rats show a number of systemic adaptations to a crowded underground habitat that is low in oxygen and high in carbon dioxide. Remarkably, brain slice tissue from adult naked mole-rats also is extremely tolerant to oxygen deprivation as indicated by maintenance of synaptic transmission under hypoxic conditions as well as by a delayed neuronal depolarization during anoxia. These characteristics resemble hypoxia tolerance in brain slices from neonates in a variety of mammal species. An important component of neonatal tolerance to hypoxia involves the subunit composition of NMDA receptors. Neonates have a high proportion of NMDA receptors with GluN2D subunits which are protective because they retard calcium entry into neurons during hypoxic episodes. Therefore, we hypothesized that adult naked mole-rats retain a protective, neonatal-like, NMDA receptor subunit profile. We used immunoblotting to assess age-related changes in NMDA receptor subunits in naked mole-rats and mice. The results show that adult naked mole-rat brain retains a much greater proportion of the hypoxia-protective GluN2D subunit compared to adult mice. However, age-related changes in other subunits (GluN2A and GluN2B) from the neonatal period to adulthood were comparable in mice and naked mole-rats. Hence, adult naked mole-rat brain only retains the neonatal NMDA receptor subunit that is associated with hypoxia tolerance. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

Climate Change and Vietnam

Science.gov (United States)

2013-11-01

suggests, such action may come at a cost against competing priorities like modernization and economic development. In that context, it bears inquiring...program including India, 29 Rajaram Panda , “Vietnam and the World: Focus on the U.S. and India

Delta-9-tetrahydrocannabinol differentially suppresses cisplatin-induced emesis and indices of motor function via cannabinoid CB(1) receptors in the least shrew.

Science.gov (United States)

Darmani, N A

2001-01-01

We have recently shown that the cannabinoid CB(1) receptor antagonist, SR 141716A, produces emesis in the least shrew (Cryptotis parva) in a dose- and route-dependent manner. This effect was blocked by delta-9-tetrahydrocannabinol (Delta(9)-THC). The present study investigates the cannabinoid receptor mechanisms by which Delta(9)-THC produces its antiemetic effects against cisplatin (20 mg/kg, i.p.)-induced emesis as well as its cannabimimetic activity profile (motor reduction) in the least shrew. Intraperitoneal administration of Delta(9)-THC (1, 2.5, 5 and 10 mg/kg) dose-dependently reduced both the percentage of animals vomiting (ID(50)=1.8+/-1.6 mg/kg) and the frequency of vomits (ID(50)=0.36+/-1.18 mg/kg) in a potent manner. The lowest significantly effective antiemetic dose of Delta(9)-THC for the latter emesis parameters was 2.5 mg/kg. Although Delta(9)-THC reduced the frequency of vomits up to 98%, it failed to completely protect all tested shrews from vomiting (80% protection). The cannabinoid CB(1) antagonist (SR 141716A) and not the CB(2) antagonist (SR 144528), reversed the antiemetic effects of Delta(9)-THC in a dose-dependent fashion. Delta(9)-THC (1, 5, 10 and 20 mg/kg, ip) suppressed locomotor parameters (spontaneous locomotor activity, duration of movement and rearing frequency) in a biphasic manner and only the 20-mg/kg dose simultaneously suppressed the triad of locomotor parameters to a significant degree. Subcutaneous (1-10 mg/kg) and intraperitoneal (0.05-40 mg/kg) injection of some doses of SR 141716A caused significant reductions in one or more components of the triad of locomotor parameters but these reductions were not dose dependent. Subcutaneous injection of SR 141716A (0.2, 1, 5 and 10 mg/kg) reversed the motor suppressant effects of a 20-mg/kg dose of Delta(9)-THC (ip) in a dose-dependent manner. Relative to its motor suppressant effects, Delta(9)-THC is a more potent antiemetic agent. Both effects are probably mediated via CB(1

Using Literature in a Course on the Vietnam War.

Science.gov (United States)

Goldstein, Jonathan

1989-01-01

Courses in Vietnam War history should incorporate Vietnamese, French, and English literary response to the war as complements to the history texts. Possibilities include an account of the French colonial experience, a required text in translation from the viewpoint of the Socialist Republic of Vietnam, and Vietnamese expatriate texts. (MSE)

Transgender at Work: Livelihoods for Transgender People in Vietnam

NARCIS (Netherlands)

Hoang, T.A.; Oosterhoff, P.

2016-01-01

The laws in the Socialist Republic of Vietnam promote equality for all citizens and refer to ‘persons’ rather than ‘men’ or ‘women’. However, because of traditional gender norms, transgender people in Vietnam are facing severe stigma and discrimination in public, in schools, at home and in the

Fostering Response to Vietnam War Literature through the Arts.

Science.gov (United States)

Johannessen, Larry R.

1997-01-01

Describes a unit on the literature of the Vietnam War (part of a college course called "Twentieth Century War Literature") which uses the arts to enhance student learning. Discusses activities and assignments in which students create visual representations, conduct research, and prepare oral reports on the Vietnam War literature they…

Lessons learned and advice from Vietnam war nurses: a qualitative study.

Science.gov (United States)

Scannell-Desch, Elizabeth A

2005-03-01

The aim of this paper is to describe guidance for nurses today from the lessons learned by nurses who served in the Vietnam War. There is little research focusing on nurses' experiences in the Vietnam War. Lessons learned and subsequent advice from nurses who served in Vietnam may be helpful to those serving in current and future wars. A Husserlian phenomenological approach was taken, using interviews with a purposive sample of Registered Nurses who were female, and had served in the United States of America armed forces in Vietnam during the war. Seven theme clusters described the lesson learned and guidance offered by the Vietnam War nurses: advice about journaling, training, caring for yourself, use of support systems, talking about your experiences, understanding the mission, and lack of preparation for war. Much can be learned from the lessons learned and advice given by Vietnam War nurses. These lessons stress that nurses need to take a pro-active role in preparing themselves for deployment to a war zone, and that institutional training for war needs to be intensive and realistic. The environmental, cultural, technological, clinical and psychosocial demands of war nursing need to be comprehensively addressed before nurses deploy to a war.

Predictive value of some hematological parameters for non-invasive and invasive mole pregnancies.

Science.gov (United States)

Abide Yayla, Cigdem; Özkaya, Enis; Yenidede, Ilter; Eser, Ahmet; Ergen, Evrim Bostancı; Tayyar, Ahter Tanay; Şentürk, Mehmet Baki; Karateke, Ates

2018-02-01

The aim of this study was to discriminate mole pregnancies and invasive forms among cases with first trimester vaginal bleeding by the utilization of some complete blood count parameters conjunct to sonographic findings and beta human chorionic gonadotropin concentration. Consecutive 257 cases with histopathologically confirmed mole pregnancies and 199 women without mole pregnancy presented with first trimester vaginal bleeding who admitted to Zeynep Kamil Women and Children's Health Training Hospital between January 2012 and January 2016 were included in this cross-sectional study. The serum beta HCG level at presentation, and beta hCG levels at 1st, 2nd and 3rd weeks of postevacuation with some parameters of complete blood count were utilized to discriminate cases with molar pregnancy and cases with invasive mole among first trimester pregnants presented with vaginal bleeding and abnormal sonographic findings. Levels of beta hCG at baseline (AUC = 0.700, p < 0.05) and 1st (AUC = 0.704, p < 0.05), 2nd (AUC = 0.870, p < 0.001) and 3rd (AUC = 0.916, p < 0.001) weeks of postevacuation period were significant predictors for the cases with persistent disease. While area under curve for mean platelet volume is 0.715, it means that mean platelet volume has 21.5% additional diagnostic value for predicting persistency in molar patients. For 8.55 cut-off point for mean platelet volume, sensitivity is 84.6% and specificity is 51.6%. Area under curve for platelet/lymphocyte ratio is 0.683 means that platelet/lymphocyte ratio has additional 18.3% diagnostic value. For 102.25 cut-off point sensitivity is 86.6% and specificity is 46.2. Simple, widely available complete blood count parameters may be used as an adjunct to other risk factors to diagnose molar pregnancies and predict postevacuation trophoblastic disease.

Proposed Training Plan to Improve Building Energy Efficiency in Vietnam

Energy Technology Data Exchange (ETDEWEB)

Yu, Sha; Evans, Meredydd

2013-01-01

Vietnam has experienced fast growth in energy consumption in the past decade, with annual growth rate of over 12 percent. This is accompanied by the fast increase in commercial energy use, driven by rapid industrialization, expansion of motorized transport, and increasing energy use in residential and commercial buildings. Meanwhile, Vietnam is experiencing rapid urbanization at a rate of 3.4 percent per year; and the majority of the growth centered in and near major cities such as Hanoi and Ho Chi Minh City. This has resulted in a construction boom in Vietnam.

"Konsesjon til radikalere" : Norges anerkjennelse av Nord-Vietnam i 1971

OpenAIRE

Sørensen, Cristian H.

2012-01-01

Emnet for oppgaven er Norges anerkjennelse av Nord-Vietnam som en selvstendig stat. Dette skjedde i 1971 mens Nord-Vietnam var i krig med Sør-Vietnam og USA. Norge var det første NATO-landet som fattet prinsippvedtak om dette, og Danmark fulgte etter. Det hele provoserte USA i så stor grad at Nixon-administrasjonen var nær ved å kalle ambassadørene sine i Oslo og København hjem. Det var regjeringen Bratteli som stod for utførelsen av anerkjennelsen etter at Arbeiderpartiet kom tilbake til reg...

75 FR 48724 - Frozen Warmwater Shrimp From Brazil, China, India, Thailand, and Vietnam

Science.gov (United States)

2010-08-11

... Warmwater Shrimp From Brazil, China, India, Thailand, and Vietnam AGENCY: United States International Trade... warmwater shrimp from Brazil, China, India, Thailand, and Vietnam. SUMMARY: The Commission hereby gives... warmwater shrimp from Brazil, China, India, Thailand, and Vietnam would be likely to lead to continuation or...

75 FR 57501 - Frozen Warmwater Shrimp From Brazil, China, India, Thailand, and Vietnam

Science.gov (United States)

2010-09-21

... Warmwater Shrimp From Brazil, China, India, Thailand, and Vietnam AGENCY: United States International Trade... warmwater shrimp from Brazil, China, India, Thailand, and Vietnam. SUMMARY: The Commission hereby gives... warmwater shrimp from Brazil, China, India, Thailand, and Vietnam would be likely to lead to continuation or...

75 FR 22424 - Frozen Warmwater Shrimp From Brazil, China, India, Thailand, and Vietnam

Science.gov (United States)

2010-04-28

... Warmwater Shrimp From Brazil, China, India, Thailand, and Vietnam AGENCY: United States International Trade... antidumping duty orders on frozen warmwater shrimp from Brazil, China, India, Thailand, and Vietnam. SUMMARY... duty orders on frozen warmwater shrimp from Brazil, China, India, Thailand, and Vietnam would be likely...

The Future of Patriotism: The War Film, The Cinema Industry, and the Vietnam Veteran Movement.

Science.gov (United States)

Camacho, Paul

1990-01-01

Examines the media's effect on attitudes about Vietnam veterans. Discusses the relationship between media and culture. Analyzes the film industry's ideological battle over Vietnam. Critiques the media's treatment of the Vietnam experience, and considers the impact of media portrayals of the war on the Vietnam Veteran's movement. (RW)

Visualization of mole fraction distribution of slow jet forming stably stratified field

International Nuclear Information System (INIS)

Fumizawa, Motoo; Hishida, Makoto

1990-01-01

An experimental study has been performed to investigate the behavior of flow and mass transfer in gaseous slow jet in which buoyancy force opposed the flow forming stably stratified field. The study has been performed to understand the basic features of air ingress phenomena at pipe rupture accident of the high temperature gas-cooled reactor. A displacement fringe technique was adopted in Mach-Zehnder interferometer to visualize the mole fraction distribution. As the result, the followings were obtained: (1) The stably stratified fields were formed in the vicinity of the outlet of the slow jet. The penetration distance of the stably stratified fields increased with Froude number. (2) Mass fraction distributions in the stably stratified fields were well correlated with the present model using the ramp mole velocity profile. (author)

The Making of "The Lessons of the Vietnam War."

Science.gov (United States)

Starr, Jerold M.

1988-01-01

Traces the development of "The Lessons of the Vietnam War," a set of units which cover legal, cultural, and historical questions of the war in greater depth than do survey textbooks. Examples of the 12 topics are "Introduction to Vietnam: Land, Culture, and History" and "Taking Sides: The War at Home." (GEA)

Lightning protection for wind turbines in Vietnam

Directory of Open Access Journals (Sweden)

Thuan Nguyen

2017-01-01

Full Text Available Wind energy has become increasingly important in the total electrical energy supply mix in Vietnam over the last few years. Small, kW turbines were installed in isolated areas a decade ago, while wind farms of several MW to few hundred MW are now being connected directly to national grid, with many additional projects in planning or under construction to fulfill an objective of 6% of the total installed capacity by 2030 (approximately 6200 MW of wind energy component. The increase in wind farm generation results in increased damage from lightning. In this paper, the annual frequency of lightning strikes to wind turbines in Vietnam is calculated using electrogeometric model. Reported lightning incidents to three major wind farms in Vietnam are summarized. Possible causes of failure are discussed, and an EMTP simulation for each incident was performed accordingly. The simulations suggest the failure mechanisms as well the potential of improved grounding to reduce lightning induced damage in future windfarms.

Evidence of greater health care needs among older veterans of the Vietnam War.

Science.gov (United States)

Brooks, Matthew S; Laditka, Sarah B; Laditka, James N

2008-08-01

This study examined self-rated health, impairments in activities of daily living, and treatment for eight health conditions among Vietnam War-era veterans, comparing those who served in Vietnam with those who served elsewhere. Data were from the nationally representative 2001 National Survey of Veterans (N = 7,907; 3,923 veterans served in Vietnam). Age-stratified ( or =60 years) analyses included multivariate logistic regression. In adjusted analyses, among those Vietnam had notably poorer self-rated health and higher stroke risk (odds ratio, 1.51; 95% confidence interval, 1.48-1.53); odds of most other conditions were lower. Among those > or =60 years of age, those who served in Vietnam had poorer self-rated health, higher cancer risk (odds ratio, 1.33; 95% confidence interval, 1.32-1.35), and more treatment for hypertension, lung conditions, stroke, and hearing loss. Results suggest greater resource use among older veterans who served in Vietnam. Clinicians and the Department of Veterans Affairs should especially note their substantially higher cancer risk.

31 CFR 500.560 - Bank accounts of official representatives of foreign governments in North Korea, North Viet-Nam...

Science.gov (United States)

2010-07-01

... representatives of foreign governments in North Korea, North Viet-Nam, Cambodia, or South Viet-Nam. 500.560... governments in North Korea, North Viet-Nam, Cambodia, or South Viet-Nam. Specific licenses are issued... Viet-Nam, Cambodia, or South Viet-Nam for transactions which are not inconsistent with the purposes of...

Investigation of the presence and antinociceptive function of muscarinic acetylcholine receptors in the African naked mole-rat (Heterocephalus glaber)

DEFF Research Database (Denmark)

Jørgensen, Kristine B.; Krogh-Jensen, Karen; Pickering, Darryl S

2016-01-01

The present study investigated the cholinergic system in the African naked mole-rat (Heterocephalus glaber) with focus on the muscarinic acetylcholine receptor subtypes M1 and M4. The protein sequences for the subtypes m 1–5 of the naked mole-rat were compared to that of the house mouse (Mus...... musculus) using basic local alignment search tool (BLAST). The presence and function of M1 and M4 was investigated in vivo, using the formalin test with the muscarinic receptor agonists xanomeline and VU0152100. Spinal cord tissue from the naked mole-rat was used for receptor saturation binding studies...

Disparate patterns of age-related changes in lipid peroxidation in long-lived naked mole-rats and shorter-lived mice.

Science.gov (United States)

Andziak, Blazej; Buffenstein, Rochelle

2006-12-01

A key tenet of the oxidative stress theory of aging is that levels of accrued oxidative damage increase with age. Differences in damage generation and accumulation therefore may underlie the natural variation in species longevity. We compared age-related profiles of whole-organism lipid peroxidation (urinary isoprostanes) and liver lipid damage (malondialdehyde) in long living naked mole-rats [maximum lifespan (MLS) > 28.3 years] and shorter-living CB6F1 hybrid mice (MLS approximately 3.5 years). In addition, we compared age-associated changes in liver non-heme iron to assess how intracellular conditions, which may modulate oxidative processes, are affected by aging. Surprisingly, even at a young age, concentrations of both markers of lipid peroxidation, as well as of iron, were at least twofold (P naked mole tats than in mice. This refutes the hypothesis that prolonged naked mole-rat longevity is due to superior protection against oxidative stress. The age-related profiles of all three parameters were distinctly species specific. Rates of lipid damage generation in mice were maintained throughout adulthood, while accrued damage in old animals was twice that of young mice. In naked mole-rats, urinary isoprostane excretion declined by half with age (P naked mole-rats is independent of oxidative stress parameters.

Blunted behavioral and c Fos responses to acidic fumes in the African naked mole-rat.

Science.gov (United States)

LaVinka, Pamela Colleen; Park, Thomas J

2012-01-01

Acidosis in the skin triggers activation of pain pathways and behaviors indicative of pain in vertebrates. The exception is the naked mole-rat, the only known vertebrate to show physiological and behavioral insensitivity to acid pain in the skin. The goal of the present study was to determine behavioral and physiological responses of this species to airborne acidic fumes, which would be expected to affect the trigeminal pain pathway in other species. Behaviorally, naked mole-rats did not avoid fumes from moderately high concentrations of acetic acid (10 and 20%), and c Fos labeling showed no increase in activity in the trigeminal nuclei and nucleus tractus solitarius. In contrast, these concentrations triggered behavioral aversion and increased Fos activity in other laboratory rodents. For a very high concentration of acetic acid (50%), naked mole-rats showed significant avoidance behavior and increased Fos labeling in the nucleus tractus solitarius caudal region, which receives vagal chemosensory information. However, there was no increase in trigeminal labeling, and in fact, activity significantly decreased. This pattern is opposite of that associated with another irritant, ammonia fumes, which elicited an increase in trigeminal but not nucleus tractus solitarius Fos labeling, and no behavioral avoidance. Behavioral avoidance of acidic fumes, but no increased labeling in the trigeminal pain nucleus is consistent with the notion of adaptations to blunt acid pain, which would be advantageous for naked mole-rats as they normally live under chronically high levels of acidosis-inducing CO(2).

Blunted behavioral and c Fos responses to acidic fumes in the African naked mole-rat.

Directory of Open Access Journals (Sweden)

Pamela Colleen LaVinka

Full Text Available Acidosis in the skin triggers activation of pain pathways and behaviors indicative of pain in vertebrates. The exception is the naked mole-rat, the only known vertebrate to show physiological and behavioral insensitivity to acid pain in the skin. The goal of the present study was to determine behavioral and physiological responses of this species to airborne acidic fumes, which would be expected to affect the trigeminal pain pathway in other species. Behaviorally, naked mole-rats did not avoid fumes from moderately high concentrations of acetic acid (10 and 20%, and c Fos labeling showed no increase in activity in the trigeminal nuclei and nucleus tractus solitarius. In contrast, these concentrations triggered behavioral aversion and increased Fos activity in other laboratory rodents. For a very high concentration of acetic acid (50%, naked mole-rats showed significant avoidance behavior and increased Fos labeling in the nucleus tractus solitarius caudal region, which receives vagal chemosensory information. However, there was no increase in trigeminal labeling, and in fact, activity significantly decreased. This pattern is opposite of that associated with another irritant, ammonia fumes, which elicited an increase in trigeminal but not nucleus tractus solitarius Fos labeling, and no behavioral avoidance. Behavioral avoidance of acidic fumes, but no increased labeling in the trigeminal pain nucleus is consistent with the notion of adaptations to blunt acid pain, which would be advantageous for naked mole-rats as they normally live under chronically high levels of acidosis-inducing CO(2.

FINANCIAL STATEMENTS ANALYSIS AND FIRMS’ VALUATION IN VIETNAM

OpenAIRE

Kim, Trang Thu

2009-01-01

Valuation is the central focus in fundamental analysis. This dissertation considers the usefulness of financial statements in predicting market values of companies in Vietnam stock market by adopting the valuation model constructed by Chung et al., (2001). The overview of Vietnam stock market; some definitions about financial statements, valuation; description of several basis valuation models and empirical evidence including the description of valuation model developed by Chung et al., (2001...

78 FR 64009 - Frozen Warmwater Shrimp From China, Ecuador, India, Malaysia, and Vietnam

Science.gov (United States)

2013-10-25

... Warmwater Shrimp From China, Ecuador, India, Malaysia, and Vietnam Determinations On the basis of the record... from China, Ecuador, India, Malaysia, and Vietnam of frozen warmwater shrimp, provided for in... China, Ecuador, India, Malaysia, and Vietnam.\\2\\ \\1\\ The record is defined in sec. 207.2(f) of the...

Occurrence of the Madras Tree Shrew Anathana ellioti (Waterhouse (Scandentia: Tupaiidae in the Biligirirangan Hills, Karnataka, India

Directory of Open Access Journals (Sweden)

U. Srinivasan

2009-05-01

Full Text Available The Madras Tree Shrew Anathana ellioti (Waterhouse 1850 is a small mammal belonging to the order Scandentia, and is endemic to peninsular India. It inhabits deciduous forests and has till date not been reported from the Biligiriranga Swamy Temple Wildlife Sanctuary (BRT WLS or the contiguous hill ranges or from anywhere else in the state of Karnataka. We provide details of nine independent sightings of this species from six locations in the BRT WLS between 2003 and 2008. Photographs of the three individuals from different locations are also presented. These records indicate an extension of the range of this species in the BRT WLS, and possibly the forests contiguous to the protected area.

Vietnam: opportunities in a developing oil and gas market

International Nuclear Information System (INIS)

Knott, T.

1993-11-01

The aim of this report is to act as an introduction to Vietnam and its oil industry opportunities for manufacturing, contracting, service and supplies companies which are seeking entry into other markets. The chapters of the report present an overview of the country, its recent history and formative events; in addition, the country's economy, industries and rebuilding process are reviewed. Detailed attention is given to trade, investment and finance, as these factors directly influence all business ventures in Vietnam, and are essential considerations in the assessment of the overall business environment. The appendices contain an extensive list of organisational contacts in Vietnam, the U.K. and elsewhere, and other useful information to support these activities. (author)

Vietnam seeks help expanding voluntary surgical contraception.

Science.gov (United States)

Piet-pelon, N J; Sukop, S

1992-07-01

Recent surveys by the Vietnamese Ministry of Health suggest that 60% of married women desire no more children. Yet only 2% of currently married women and less than 1/2 of 1% of their partners use sterilization. Underscoring the high unmet need for effective family planning, over 1 million abortions (legal in Vietnam for the past 20 years) are performed annually. This rate corresponds to 1 abortion for every live birth. The Ministry of Health has recently welcomed a variety of organizations, including AVSC, whose assistance can help expand the country's family planning programs. Sorely lacking in supplies, equipment, and trained personnel, Vietnam has merited priority status--2nd only to China and India--from the UNFPA, which has committed $36 million over the next 4 years. Other organizations currently working in Vietnam include the Population Council, the Population Crisis Committee, and the International Planned Parenthood Federation. Despite enormous casualties during the war years, and a decrease since the 1970s in average family size from 6 to 4 children, the population of Vietnam has continued to grow rapidly, far outpacing economic growth. Currently 67 million, the population is expected to reach 80 million by the year 2000. The average Vietnamese annual income is only $195, among the lowest in the world. Doi moi, the process of economic reform begun in 1986, coupled with new government incentives for families who have no more than 2 children, is changing the face of family planning in Vietnam. Newly opened pharmacies sell imported birth control pills and condoms (to those who can afford them), while government hospitals and health clinics provide mainly IUDs, in addition to limited supplies of pills and condoms. Throughout the country, some 8000 community-level health centers are staffed by nurse-midwives trained in family planning. Voluntary sterilization is available at the district, provincial, and national hospitals. All married women may obtain family

Modeling the impact of rubella vaccination in Vietnam.

Science.gov (United States)

Vynnycky, Emilia; Yoshida, Lay Myint; Huyen, Dang Thi Thanh; Trung, Nguyen Dac; Toda, Kohei; Cuong, Nguyen Van; Thi Hong, Duong; Ariyoshi, Koya; Miyakawa, Masami; Moriuchi, Hiroyuki; Tho, Le Huu; Nguyen, Hien Anh; Duc Anh, Dang; Jit, Mark; Hien, Nguyen Tran

2016-01-01

Supported by GAVI Alliance, measles-rubella vaccination was introduced in Vietnam in 2014, involving a mass campaign among 1-14 year olds and routine immunization of children aged 9 months. We explore the impact on the incidence of Congenital Rubella Syndrome (CRS) during 2013-2050 of this strategy and variants involving women aged 15-35 years. We use an age and sex-structured dynamic transmission model, set up using recently-collected seroprevalence data from Central Vietnam, and also consider different levels of transmission and contact patterns. If the serological profile resembles that in Central Vietnam, the planned vaccination strategy could potentially prevent 125,000 CRS cases by 2050 in Vietnam, despite outbreaks predicted in the meantime. Targeting the initial campaign at 15-35 year old women with or without children aged 9 months-14 years led to sustained reductions in incidence, unless levels of ongoing transmission were medium-high before vaccination started. Assumptions about contact greatly influenced predictions if the initial campaign just targeted 15-35 year old women and/or levels of ongoing transmission were medium-high. Given increased interest in rubella vaccination, resulting from GAVI Alliance funding, the findings are relevant for many countries.

Tobacco Control Policies in Vietnam: Review on MPOWER Implementation Progress and Challenges.

Science.gov (United States)

Minh, Hoang Van; Ngan, Tran Thu; Mai, Vu Quynh; My, Nguyen Thi Tuyet; Chung, Le Hong; Kien, Vu Duy; Anh, Tran Tuan; Ngoc, Nguyen Bao; Giap, Vu Van; Cuong, Nguyen Manh; Manh, Pham Duc; Giang, Kim Bao

2016-01-01

In Vietnam, the WHO Framework Convention on Tobacco Control (WHO FCTC) took effect in March 2005 while MPOWER has been implemented since 2008. This paper describes the progress and challenges of implementation of the MPOWER package in Vietnam. We can report that, in term of monitoring, Vietnam is very active in the Global Tobacco Surveillance System, completing two rounds of the Global Adult Tobacco Survey (GATS) and three rounds of the Global Youth Tobacco Survey (GYTS). To protect people from tobacco smoke, Vietnam has issued and enforced a law requiring comprehensive smoking bans at workplaces and public places since 2013. Tobacco advertising and promotion are also prohibited with the exception of points of sale displays of tobacco products. Violations come in the form of promotion girls, corporate social responsibility activities from tobacco manufacturers and packages displayed by retail vendors. Vietnam is one of the 77 countries that require pictorial health warnings to be printed on cigarette packages to warn about the danger of tobacco and the warnings have been implemented effectively. Cigarette tax is 70% of factory price which is equal to less than 45% of retail price and much lower than the recommendation of WHO. However, Vietnam is one of the very few countries that require manufacturers and importers to make "compulsory contributions" at 1-2% of the factory price of cigarettes sold in Vietnam for the establishment of a Tobacco Control Fund (TCF). The TCF is being operated well. In 2015, 67 units of 63 provinces/cities, 22 ministries and political-social organizations and 6 hospitals received funding from TCF to implement a wide range of tobacco control activities. Cessation services have been starting with a a toll-free quit-line but need to be further strengthened. In conclusion, Vietnam has constantly put efforts into the tobacco control field with high commitment from the government, scientists and activists. Though several remarkable achievements

Estimating the extra cost of living with disability in Vietnam.

Science.gov (United States)

Minh, Hoang Van; Giang, Kim Bao; Liem, Nguyen Thanh; Palmer, Michael; Thao, Nguyen Phuong; Duong, Le Bach

2015-01-01

Disability is shown to be both a cause and a consequence of poverty. However, relatively little research has investigated the economic cost of living with a disability. This study reports the results of a study on the extra cost of living with disability in Vietnam in 2011. The study was carried out in eight cities/provinces in Vietnam, including Hanoi and Ho Chi Minh cities (two major metropolitan in Vietnam) and six provinces from each of the six socio-economic regions in Vietnam. Costs are estimated using the standard of living approach whereby the difference in incomes between people with disability and those without disability for a given standard of living serves as a proxy for the cost of living with disability. The extra cost of living with disability in Vietnam accounted for about 8.8-9.5% of annual household income, or valued about US$200-218. Communication difficulty was shown to result in highest additional cost of living with disability and self-care difficulty was shown to lead to the lowest levels of extra of living cost. The extra cost of living with disability increased as people had more severe impairment. Interventions to promote the economic security of livelihood for people with disabilities are needed.

Greening Food Processing Industry in Vietnam: Putting Industrial Ecology to Work

OpenAIRE

Tran Thi My Dieu

2003-01-01

The significant contribution to Vietnam's gross domestic product over the years give evidence of the important role of food processing industry in the economic and industrial development of the country. This is even more relevant from now onwards, as it is Vietnam's development strategy to become one of the top agricultural countries in the world by the year 2010. However, it is not difficult to recognize that the rapid growth of food processing industry in Vietnam goes together with environm...

77 FR 32873 - Commemoration of the 50th Anniversary of the Vietnam War

Science.gov (United States)

2012-06-01

... the 50th Anniversary of the Vietnam War Proclamation 8830--National Hurricane Preparedness Week, 2012... Anniversary of the Vietnam War By the President of the United States of America A Proclamation As we observe the 50th anniversary of the Vietnam War, we reflect with solemn reverence upon the valor of a...

The China Factor in U.S.-Vietnam Relations

Science.gov (United States)

2012-03-01

Sailors Who Sacrificed Their Lives in the Truong Sa Islands,” Voice of Vietnam News, 10 May 2010; “Old Problem , New Threats,” Bangkok Post, 30 May 2011...Pacific Trade Policies for the Vietnam Ministry of Industry and Trade, 70 percent of Vietnam’s imports from China consist of essential materials used in...the production of exported goods, including materials and equipment, steel, chemicals, and petroleum, as well as fabric, garment, and footwear

Study on external exposure doses from terrestrial radioactivity in Southern Vietnam

International Nuclear Information System (INIS)

Huy, N.Q.; Luyen, T.V.

2012-01-01

This paper presents the radioactivity concentrations of 226 Ra, 232 Th and 40 K for 106 samples of surface soil collected in Southern Vietnam. The mean values of mass activity of radionuclides 226 Ra, 232 Th and 40 K for Southern Vietnam are 28.6, 50.7 and 292.6 Bq kg -1 , respectively, which lead to the population-weighted absorbed dose rate of 54.5 nGy h -1 . The average annual effective doses outdoors, indoors and in total of Southern Vietnam are estimated to be 0.067, 0.374 and 0. 441 mSv, respectively. The radium equivalent activity and the external hazard index of soil in Southern Vietnam are in the range 23.2-254.1 Bq kg -1 and 0.06-0.69, respectively. (author)

Study on external exposure doses from terrestrial radioactivity in Southern Vietnam

International Nuclear Information System (INIS)

Huy, N. Q.; Luyen, T. V.

2006-01-01

This paper presents the radioactivity concentrations of 226 Ra, 232 Th and 40 K for 106 samples of surface soil collected in Southern Vietnam. The mean values of mass activity of radionuclides 226 Ra, 232 Th and 40 K for Southern Vietnam are 28.6, 50.7 and 292.6 Bq kg -1 , respectively, which lead to the population-weighted absorbed dose rate of 54.5 nGy h -1 . The average annual effective doses outdoors, indoors and in total of Southern Vietnam are estimated to be 0.067, 0.374 and 0.441 mSv, respectively. The radium equivalent activity and the external hazard index of soil in Southern Vietnam are in the range 23.2-254.1 Bq kg -1 and 0.06-0.69, respectively. (authors)

Constructions of gender in Vietnam: in pursuit of the 'Three Criteria'.

Science.gov (United States)

Schuler, Sidney Ruth; Hoang, Tu Anh; Vu, Song Ha; Tan, Hung Minh; Bui, Thi Thanh Mai; Pham, Vu Thien

2006-01-01

Vietnam has advanced far beyond most other developing countries and, indeed, surpasses many developed countries in adopting a legal framework based on gender equality, and in creating institutions and programmes to support women's advancement. Inegalitarian gender norms have also persisted, however. The Vietnam Women's Union promotes women's educational, political and economic advancement but simultaneously exhorts women to pay attention to their Confucian role of maintaining family hierarchy and harmony. This paper presents findings from qualitative research examining gender relations at the grassroots level in central Vietnam. It argues that the Vietnam Women's Union could support women more effectively by promoting greater diversity in gender norms and by initiating a public discussion to address the pressures women face in trying to achieve ideals that are often experienced as contradictory and unattainable.

The role of trade unions in Vietnam

DEFF Research Database (Denmark)

Torm, Nina Elisabeth

2014-01-01

On the basis of matched employer–employee data from 2007 to 2009, this paper examines the union wage gap among small and medium non-state manufacturing enterprises in Vietnam. Controlling for both worker and firm characteristics, the results provide evidence that union members earn higher wages t...... than non-members, and are more likely to receive social benefits.Within unionised firms, a substantial wage premium is revealed for workers employed in Southern firms, a finding which among other factors may be attributed to historical differences between the North and South of Vietnam....

Naked mole-rat has increased translational fidelity compared with the mouse, as well as a unique 28S ribosomal RNA cleavage.

Science.gov (United States)

Azpurua, Jorge; Ke, Zhonghe; Chen, Iris X; Zhang, Quanwei; Ermolenko, Dmitri N; Zhang, Zhengdong D; Gorbunova, Vera; Seluanov, Andrei

2013-10-22

The naked mole-rat (Heterocephalus glaber) is a subterranean eusocial rodent with a markedly long lifespan and resistance to tumorigenesis. Multiple data implicate modulation of protein translation in longevity. Here we report that 28S ribosomal RNA (rRNA) of the naked mole-rat is processed into two smaller fragments of unequal size. The two breakpoints are located in the 28S rRNA divergent region 6 and excise a fragment of 263 nt. The excised fragment is unique to the naked mole-rat rRNA and does not show homology to other genomic regions. Because this hidden break site could alter ribosome structure, we investigated whether translation rate and amino acid incorporation fidelity were altered. We report that naked mole-rat fibroblasts have significantly increased translational fidelity despite having comparable translation rates with mouse fibroblasts. Although we cannot directly test whether the unique 28S rRNA structure contributes to the increased fidelity of translation, we speculate that it may change the folding or dynamics of the large ribosomal subunit, altering the rate of GTP hydrolysis and/or interaction of the large subunit with tRNA during accommodation, thus affecting the fidelity of protein synthesis. In summary, our results show that naked mole-rat cells produce fewer aberrant proteins, supporting the hypothesis that the more stable proteome of the naked mole-rat contributes to its longevity.

Emergence of Integrated Water Resources Management : Measuring implementation in Vietnam

NARCIS (Netherlands)

Akkerman, M.; Khanh, N.T.; Witter, M.; Rutten, M.M.

2015-01-01

Recently, the changes in laws and regulations, such as the revised Law on Water Resources in 2012, have sought to provide a legal framework for the internationally recognized practices of Integrated Water Resources Management (IWRM) in Vietnam. With IWRM being a novel approach for Vietnam, it would

Hydatidiform mole and fetus with normal karyotype: support of a separate entity

DEFF Research Database (Denmark)

Vejerslev, L O; Sunde, L; Hansen, B F

1991-01-01

Repetitive hydatidiform mole was observed in four pregnancies. The pregnancies presented with heavy bleeding and vomiting, but the post-evacuation courses were uncomplicated, with rapid regression of serum hCG levels. Cytogenetic investigations, analyses of restriction fragment length polymorphis...

Migration and Persistence of Human Influenza A Viruses, Vietnam, 2001–2008

Science.gov (United States)

Le, Mai Quynh; Lam, Ha Minh; Cuong, Vuong Duc; Lam, Tommy Tsan-Yuk; Halpin, Rebecca A; Wentworth, David E; Hien, Nguyen Tran; Thanh, Le Thi; Phuong, Hoang Vu Mai; Horby, Peter

2013-01-01

Understanding global influenza migration and persistence is crucial for vaccine strain selection. Using 240 new human influenza A virus whole genomes collected in Vietnam during 2001–2008, we looked for persistence patterns and migratory connections between Vietnam and other countries. We found that viruses in Vietnam migrate to and from China, Hong Kong, Taiwan, Cambodia, Japan, South Korea, and the United States. We attempted to reduce geographic bias by generating phylogenies subsampled at the year and country levels. However, migration events in these phylogenies were still driven by the presence or absence of sequence data, indicating that an epidemiologic study design that controls for prevalence is required for robust migration analysis. With whole-genome data, most migration events are not detectable from the phylogeny of the hemagglutinin segment alone, although general migratory relationships between Vietnam and other countries are visible in the hemagglutinin phylogeny. It is possible that virus lineages in Vietnam persisted for >1 year. PMID:24188643

Phylodynamic analysis of the dissemination of HIV-1 CRF01_AE in Vietnam.

Science.gov (United States)

Liao, Huanan; Tee, Kok Keng; Hase, Saiki; Uenishi, Rie; Li, Xiao-Jie; Kusagawa, Shigeru; Thang, Pham Hong; Hien, Nguyen Tran; Pybus, Oliver G; Takebe, Yutaka

2009-08-15

To estimate the epidemic history of HIV-1 CRF01_AE in Vietnam and adjacent Guangxi, China, we determined near full-length nucleotide sequences of CRF01_AE from a total of 33 specimens collected in 1997-1998 from different geographic regions and risk populations in Vietnam. Phylogenetic and Bayesian molecular clock analyses were performed to estimate the date of origin of CRF01_AE lineages. Our study reconstructs the timescale of CRF01_AE expansion in Vietnam and neighboring regions and suggests that the series of CRF01_AE epidemics in Vietnam arose by the sequential introduction of founder strains into new locations and risk groups. CRF01_AE appears to have been present among heterosexuals in South-Vietnam for more than a decade prior to its epidemic spread in the early 1990s. In the late 1980s, the virus spread to IDUs in Southern Vietnam and subsequently in the mid-1990s to IDUs further north. Our results indicate the northward dissemination of CRF01_AE during this time.

Social science research on HIV in Vietnam: a critical review and future directions.

Science.gov (United States)

Dao, Amy; Hirsch, Jennifer S; Giang, Le Minh; Parker, Richard G

2013-01-01

Social science research can enhance the response to Vietnam's growing HIV epidemic by capturing the country's rapidly changing social and political context. The present paper reviews the published, peer-reviewed and English-language social science literature on HIV in Vietnam in order to identify critical theoretical and substantive gaps, while laying the groundwork for future research. We found four broad foci for work on the social context of HIV and AIDS in Vietnam: the cultural meanings and social relationships that shape Vietnam's HIV epidemic; stigma and discrimination; social inequality and structural violence as contributors to HIV risk; and, finally, how broader global and social systems shape Vietnam's HIV epidemic. We signal the particular need for additional research on the effects of the media on attitudes towards HIV and AIDS, on social movements, and on health systems, as well as on a number of other key areas. Work along these lines, in addition to more effective communication of policy-relevant findings to those responsible for the development and implementation of policies and programmes, will strengthen Vietnam's response to HIV and AIDS.

The reproductive biology of the giant Zambian mole-rat, Cryptomys ...

African Journals Online (AJOL)

1994-09-29

Sep 29, 1994 ... gala (12° 27'S, 2T51'E) in the Copperbelt of northern Zam- hia. ... mole-rat, a pair of animals and a group comprising one male and three females .... Figure 1 Changes In bouy mass of a captive female Cr.vptom.vs mechowi ... The sex distribution was .... 'Ine social Cryptomys species are chmacteril,ed hy.

77 FR 76170 - Presumption of Exposure to Herbicides for Blue Water Navy Vietnam Veterans Not Supported

Science.gov (United States)

2012-12-26

... during the Vietnam War. After careful review of the IOM report, the Secretary determines that the... served in deep-water naval vessels off the coast of Vietnam during the Vietnam War are referred to as... DEPARTMENT OF VETERANS AFFAIRS Presumption of Exposure to Herbicides for Blue Water Navy Vietnam...

78 FR 7452 - Steel Wire Garment Hangers From Vietnam; Determinations

Science.gov (United States)

2013-02-01

...), that an industry in the United States is materially injured by reason of imports of steel wire garment... Garment Hangers From Vietnam; Determinations On the basis of the record \\1\\ developed in the subject... duty orders on steel wire garment hangers from Vietnam. Background The Commission instituted these...

Community structure variability of Uropodina mites (Acari: Mesostigmata) in nests of the common mole, Talpa europaea, in Central Europe.

Science.gov (United States)

Napierała, Agnieszka; Mądra, Anna; Leszczyńska-Deja, Kornelia; Gwiazdowicz, Dariusz J; Gołdyn, Bartłomiej; Błoszyk, Jerzy

2016-04-01

Underground nests of Talpa europaea, known as the common mole, are very specific microhabitats, which are also quite often inhabited by various groups of arthropods. Mites from the suborder Uropodina (Acari: Mesostigmata) are only one of them. One could expect that mole nests that are closely located are inhabited by communities of arthropods with similar species composition and structure. However, results of empirical studies clearly show that even nests which are close to each other can be different both in terms of the species composition and abundance of Uropodina communities. So far, little is known about the factors that can cause these differences. The major aim of this study was to identify factors determining species composition, abundance, and community structure of Uropodina communities in mole nests. The study is based on material collected during a long-term investigation conducted in western parts of Poland. The results indicate that the two most important factors influencing species composition and abundance of Uropodina communities in mole nests are nest-building material and depth at which nests are located. Composition of Uropodina communities in nests of moles was also compared with that of other microhabitats (e.g. rotten wood, forest litter, soil) based on data from 4421 samples collected in Poland. Communities of this habitat prove most similar to these of open areas, especially meadows, as well as some forest types.

Tax corruption and private sector development in Vietnam

OpenAIRE

Nguyen, Ngoc Anh; Doan, Quang Hung; Tran-Nam, Binh

2017-01-01

This article aims to examine the impact of tax corruption on private sector development in Vietnam. It is motivated by two separate but related considerations. First, despite the seriousness of the phenomenon of corruption, there is a paucity of rigorous empirical research of corruption, particularly tax corruption, in Vietnam. Secondly, ineffective control of corruption is viewed as a cause of Vietnam’s recent total factor productivity (TFP) slowdown or its poor industrial policy, both of wh...

VIETNAM IN 1948: AN INTERNATIONAL HISTORY PERSPECTIVE

Directory of Open Access Journals (Sweden)

Ang Cheng Guan

2009-01-01

Full Text Available This paper revisits the year 1948 in an effort to determine whether 1948 can be considered the starting point of the Cold War in Vietnam. Historical periodisation is a tricky affair, and it is often difficult to pinpoint the genesis of events. By reconstructing the political and military developments in 1948 from the indigenous perspective as well as from regional and international perspectives that directly impinged on Vietnam, I hope to ascertain whether Vietnam’s war of liberation was indeed transformed into a “Cold War” from 1948 onwards—in other words, whether it was in 1948 that the Vietnamese struggle assumed an ideological complexion that shifted from nationalist/anti-colonial sentiment to include communist/anti-capitalist sentiment as well. Before we embark on our consideration of the year 1948, it is useful to recount in broad brush-strokes some key developments in Vietnam leading up to 1948. In order to put the year 1948 in context, it is also necessary to consider in some detail two key developments in 1947.

Distributional records of shrews (Mammalia, Soricomorpha, Soricidae) from Northern Central America with the first record of Sorex from Honduras

Science.gov (United States)

Woodman, Neal; Matson, John O.; McCarthy, Timothy J.; Eckerlin, Ralph P.; Bulmer, Walter; Ordonez-Garza, Nicte

2012-01-01

Short term surveys for small mammals in Guatemala and Honduras during 1992–2009 provided important new records for 12 taxa of shrews from 24 localities. These locality records expand the known geographic distributions for five species and for the genus Sorex Linnaeus, 1758: the geographic range of Cryptotis goodwini Jackson, 1933, now includes the Sierra de las Minas, Guatemala, and several isolated highlands in western Honduras; the known distribution of Cryptotis mayensis (Merriam, 1901) is increased with the first definite modern record for this shrew from Guatemala; Cryptotis merriami Choate, 1970, is now known to occur in the Sierra de las Minas and the Sierra del Merendon, Guatemala, as well as the isolated Sierra de Omoa and Montana de La Muralla in Honduras, and its documented elevational range (600–1720 m) is expanded; records of Sorex veraepacis Alston, 1877, expand the known distribution of this species to include the Sierra de Yalijux, Guatemala; and discovery of Sorex salvini Merriam, 1897, at Celaque, Honduras (1825–3110 m), represents a considerable extension of the geographic range of the species, and it is the first record of the genus Sorex from Honduras. In addition, the first record of potential syntopy among C. goodwini, C merriami, and Cryptotis orophilus (J.A. Allen, 1895), is reported at an elevation of 1430 m in the Sierra de Celaque, Honduras. Information associated with these records contributes substantially to knowledge of habitat use, elevational distributions, reproductive patterns, diet, and parasites of the species encountered. General patterns include the first evidence that Neotropical species of soricids have smaller litters than their temperate congeners.

The unusual state of the cumulus oophorus and of sperm behaviour within it, in the musk shrew, Suncus murinus.

Science.gov (United States)

Bedford, J M; Mori, T; Oda, S

1997-05-01

In the musk shrew, Suncus murinus, the behaviour of the cumulus-egg complex and its interaction with spermatozoa were unusual in several respects. The cumulus oophorus was ovulated about 15.5 h after mating or treatment with hCG as a hyaluronidase-insensitive matrix-free ball of cells which remained for relatively long periods of about 14 h around fertilized, and for about 24 h around unfertilized eggs. As a probable function of the small number of up to about 10 or 20 spermatozoa that generally reached the oviduct ampulla from isthmic crypts, there was often a delay of up to 10 h after ovulation before most eggs were penetrated. Soon after ovulation, however, the corona radiata retreated progressively from the zona pellucida, creating a closed perizonal space within the cumulus oophorus. Usually, most spermatozoa that did reach the ampulla were found within a cumulus and generally within that perizonal space. However, whereas the acrosome was intact among the few free ampullary spermatozoa, and in those adhering to the zona of cumulus-free eggs after delayed mating, all spermatozoa seen moving within the cumulus or adhering to the zona of unfertilized eggs had shed the giant acrosome. In accord with current observations in other shrews, the cumulus in Suncus may therefore function not only to sequester spermatozoa, but also as an essential mediator of fertilization-probably by inducing the acrosome reaction. In the absence of the acrosomal carapace that expresses the zona receptors in most mammals, fertilizing Suncus spermatozoa could use an unusual array of barbs on the exposed perforatorium to attach to the zona pellucida.

Evidência molecular da ocorrência de um fitoplasma associado ao lenho mole da macieira

OpenAIRE

Ribeiro,Luiz Fernando Caldeira; Bedendo,Ivan Paulo; Sanhueza,Rosa Maria Valdebenito

2007-01-01

O lenho mole da macieira é uma doença relevante em diversas partes do mundo. Sintomas típicos desta doença têm sido observados em pomares instalados em estados do sul do território brasileiro desde a década de oitenta. Enxertia tem revelado a natureza infecciosa da doença e a observação de corpúsculos filamentosos no floema tem evidenciado possível associação com fitoplasma. No presente trabalho plantas com sintomas de lenho mole foram coletadas em pomar comercial, visando demonstrar a presen...

[Complete hydatiforme mole in Morocco: epidemiological and clinical study].

Science.gov (United States)

Boufettal, H; Coullin, P; Mahdaoui, S; Noun, M; Hermas, S; Samouh, N

2011-09-01

Complete hydatidiform moles (CHM) are a real public health problem, especially in the "southern countries" and Asia, because of their impact on the female reproduction and the risk to progression to either invasive mole or choriocarcinoma. We collected the cases of CHM referred to our department over a period of ten years (2000 to 2009). We will present our results, emphasize the modalities of diagnosis, treatment and evolution, with a review of literature. During this study, we identified 254 cases of CHM, and recorded 57,987 births and 1627 abortions. Their incidence was 0.43% of pregnancies. The mean age of our patients is 25 years old (16 to 55). Relative risk observed was much increased among women under 20 years old (×6.8) and those over 40 years old (×15). Both of nulliparous and primiparous patients represented 52.3% of the cohort. Eighty-five percent of patients belonged to an agricultural environment associated with a low socio-economic status. Uterine bleeding was the most common symptom accounting for 93.7%. Toxic syndrome was present in 18.5% of patients. Physical examination showed a highly increased uterine size in 85% of cases associated with lateral uterine mass in 25% of cases. The diagnosis was suspected using ultrasonography in all cases associated with an elevated level of plasmatic β-human chorionic gonadotrophin (βhCG). All cases were confirmed histologically. Treatment used was endo-uterine aspiration in all cases. Recurrence of CHM was documented in 25 patients or 9.4%. Neoplasic progression was observed for 6.3% of cases. All of them have evolved into remission with chemotherapy. CHM continue to be a public health problem in Morocco, their incidence is among the highest ones. In fact, this studied population corresponds to the lowest socio-economic status and generally described as population at risk. It is subject to drastic weather's conditions causing loss of fresh products. Extreme ages and degree of parity are also risk factors

The Role of Vietnam in The ASEAN Regional Security Cooperation: From Mechanism Construction to Dispute Settlement

Directory of Open Access Journals (Sweden)

Li Chunxia

2016-12-01

Full Text Available In the context of the integration of ASEAN, Vietnam recognized that the strategic role of ASEAN is in its diplomacy. At the same time, to further improve the status in the region and in the international community, Vietnam has actively been participating in ASEAN affairs. Vietnam not only promoted the integration process of ASEAN, but also promoted the political security cooperation of ASEAN, in which Vietnam has advantages and wants to play a leading role. On the one hand, Vietnam promotes the construction of political security cooperation mechanisms, such as ARF, ADMM+, and so on; on the other hand, Vietnam took the South China Sea as a common concern, actively appeals for a common ASEAN position, to maximize its own benefit. Vietnam will further enhance and consolidate its status and role in ASEAN in the future.

Use of modern contraceptives among married women in Vietnam: a multilevel analysis using the Multiple Indicator Cluster Survey (2011) and the Vietnam Population and Housing Census (2009).

Science.gov (United States)

Vu, Lan Thi Hoang; Oh, Juhwan; Bui, Quyen Thi-Tu; Le, Anh Thi-Kim

2016-01-01

The prevalence of modern contraceptive use is an important indicator that reflects accessibility to reproductive health services. Satisfying unmet needs for family planning alone could reduce the number of maternal deaths by almost a third. This study uses multiple data sources to examine multilevel factors associated with the use of modern contraceptives among married women in Vietnam aged 15-49 years. Data from different national surveys (Vietnam Population and Housing Census, Vietnam Living Standard Survey, and Multiple Indicator Cluster Survey) were linked to create a dataset including individual and contextual (provincial) variables (N=8,341). Multilevel modeling was undertaken to examine the impact of both individual and provincial characteristics on modern contraceptive use. Odds ratios (ORs) and 95% confidence intervals (CIs) are reported. Individual factors significantly associated with the use of modern contraceptives were age 30-34 years (reference 15-19 years) (OR=1.63); high socioeconomic status (SES) (OR=0.8); having two living children (OR=2.4); and having a son (OR=1.4). The provincial poverty rate mediated the association between the individual's SES and the likelihood of using modern contraceptives. The proportion of women in Vietnam using modern contraceptive methods has remained relatively high in recent years with significant variation across Vietnam's 63 provinces. Women of lower SES are more likely to use modern contraceptive methods, especially in the poorer provinces. Achieving access to universal reproductive health is one of the Millennium Development Goals. Vietnam must continue to make progress in this area.

Current status of taeniasis and cysticercosis in Vietnam.

Science.gov (United States)

Van De, Nguyen; Le, Thanh Hoa; Lien, Phan Thi Huong; Eom, Keeseon S

2014-04-01

Several reports on taeniasis and cysticercosis in Vietnam show that they are distributed in over 50 of 63 provinces. In some endemic areas, the prevalence of taeniasis was 0.2-12.0% and that of cysticercosis was 1.0-7.2%. The major symptoms of taeniasis included fidgeted anus, proglottids moving out of the anus, and proglottids in the feces. Clinical manifestations of cysticercosis in humans included subcutaneous nodules, epileptic seizures, severe headach, impaired vision, and memory loss. The species identification of Taenia in Vietnam included Taenia asiatica, Taenia saginata, and Taenia solium based on combined morphology and molecular methods. Only T. solium caused cysticercosis in humans. Praziquantel was chosen for treatment of taeniasis and albendazole for treatment of cysticercosis. The infection rate of cysticercus cellulosae in pigs was 0.04% at Hanoi slaughterhouses, 0.03-0.31% at provincial slaughterhouses in the north, and 0.9% in provincial slaughterhouses in the southern region of Vietnam. The infection rate of cysticercus bovis in cattle was 0.03-2.17% at Hanoi slaughterhouses. Risk factors investigated with regard to transmission of Taenia suggested that consumption of raw meat (eating raw meat 4.5-74.3%), inadequate or absent meat inspection and control, poor sanitation in some endemic areas, and use of untreated human waste as a fertilizer for crops may play important roles in Vietnam, although this remains to be validated.

Identifying and Improving the image of Vietnam Tourism as a Tourism destination among Finnish tourist

OpenAIRE

Pham, Anh

2012-01-01

This writing attempts to identify the images of Vietnam as a tourism destination for Finnish tourists and suggests marketing solution for Vietnamese traveling company to improve the images of Vietnam by enhancing marketing activities in the Finnish market. Saigontourist Transportation Corporation (STC), Vietnam which is a commissioner of this thesis project, has provided updated information about the current situation of tourism in Vietnam as well as marketing activities of company durin...

A cytosolic protein factor from the naked mole-rat activates proteasomes of other species and protects these from inhibition

Science.gov (United States)

Rodriguez, Karl A.; Osmulski, Pawel A.; Pierce, Anson; Weintraub, Susan T.; Gaczynska, Maria; Buffenstein, Rochelle

2015-01-01

The naked mole-rat maintains robust proteostasis and high levels of proteasome-mediated proteolysis for most of its exceptional (~31y) life span. Here, we report that the highly active proteasome from the naked mole-rat liver resists attenuation by a diverse suite of proteasome-specific small molecule inhibitors. Moreover, mouse, human, and yeast proteasomes exposed to the proteasome-depleted, naked mole-rat cytosolic fractions, recapitulate the observed inhibition resistance, and mammalian proteasomes also show increased activity. Gel filtration coupled with mass spectrometry and atomic force microscopy indicates that these traits are supported by a protein factor that resides in the cytosol. This factor interacts with the proteasome and modulates its activity. Although HSP72 and HSP40 (Hdj1) are among the constituents of this factor, the observed phenomenon, such as increasing peptidase activity and protecting against inhibition cannot be reconciled with any known chaperone functions. This novel function may contribute to the exceptional protein homeostasis in the naked mole-rat and allow it to successfully defy aging. PMID:25018089

Effects of ultraviolet radiation on mole rats kidney: A histopathologic and ultrastructural study

Directory of Open Access Journals (Sweden)

Hüseyin Türker

2014-04-01

Full Text Available The purpose of this study was to realize the ultrastructural effects of ultraviolet radiation on the kidney tissue cells of mole rats (Spalax leucodon. The mole rats of 180–200 g body weight were divided into the control and radiation-trial groups. The control group was not given any radiation. The other groups were irradiated with artificially produced UVC radiation for 14, 28 and 60 days. The kidney tissue samples were prepared at the end of experiments and analyzed by the light and electron microscope. Several effects were observed in the kidney tissues cells analyzed in accordance with the dose magnitude of radiation. These results clearly show the detrimental effects of UVC radiation on kidney tissue cells in exposure periods dependent on radiation dose and exposure time.

The Vietnam Petroleum Industry: Positioned for Growth but Ripe for Regional Complications

Science.gov (United States)

2013-10-30

monopolistic character of PVN means the Vietnamese government is a major part of all aspects of the industry. Secondly, faced with increasing demand for...2013, JSTOR. 17 “U.S. EIA, “Vietnam” 20 18 Trong Vu and Simon Hall, “Oil Market Changes as Vietnam Build Another Refinery,” The Wall...Vietnam to Push Ahead with Offshore Exploration.” 23 Ibid. 24 Ibid. 25 Vu and Hall, “Oil Market Changes as Vietnam Build Another Refinery

Legal Framework of the Water Sector in Vietnam

OpenAIRE

Nguyen, Thi Phuong Loan

2010-01-01

Since 1986 and especially during the early 90s, environmental protection has become a constitutional principle in Vietnam as regulated by Articles 17 and 29 of the 1992 Constitution. The first Law on Environmental Protection, passed by the National Assembly on December 27, 1993 created a foundation for environmental legislation becoming an important field in Vietnam’s legal system. In the following, in January 1999, Vietnam enacted its very first Law on Water Resources (No. 08/1998/QH10) aimi...

Comparison of atmospheric CO2 mole fractions and source-sink characteristics at four WMO/GAW stations in China

Science.gov (United States)

Cheng, Siyang; Zhou, Lingxi; Tans, Pieter P.; An, Xingqin; Liu, Yunsong

2018-05-01

As CO2 is a primary driving factor of climate change, the mole fraction and source-sink characteristics of atmospheric CO2 over China are constantly inferred from multi-source and multi-site data. In this paper, we compared ground-based CO2 measurements with satellite retrievals and investigated the source-sink regional representativeness at China's four WMO/GAW stations. The results indicate that, firstly, atmospheric CO2 mole fractions from ground-based sampling measurement and Greenhouse Gases Observing Satellite (GOSAT) products reveal similar seasonal variation. The seasonal amplitude of the column-averaged CO2 mole fractions is smaller than that of the ground-based CO2 at all stations. The extrema of the seasonal cycle of ground-based and column CO2 mole fractions are basically synchronous except a slight phase delay at Lin'an (LAN) station. For the two-year average, the column CO2 is lower than ground-based CO2, and both of them reveal the lowest CO2 mole fraction at Waliguan (WLG) station. The lowest (∼4 ppm) and largest (∼8 ppm) differences between the column and ground-based CO2 appear at WLG and Longfengshan (LFS) stations, respectively. The CO2 mole fraction and its difference between GOSAT and ground-based measurement are smaller in summer than in winter. The differences of summer column CO2 among these stations are also much smaller than their ground-based counterparts. In winter, the maximum of ground-based CO2 mole fractions and the greatest difference between the two (ground-based and column) datasets appear at the LFS station. Secondly, the representative areas of the monthly CO2 background mole fractions at each station were found by employing footprints and emissions. Smaller representative areas appeared at Shangdianzi (SDZ) and LFS, whereas larger ones were seen at WLG and LAN. The representative areas in summer are larger than those in winter at WLG and SDZ, but the situation is opposite at LAN and LFS. The representative areas for the

Anemia and intestinal parasite infection in school children in rural Vietnam

NARCIS (Netherlands)

Thi, Le H.; Brouwer, I.D.; Verhoef, H.; Khan, N.C.; Kok, F.J.

2007-01-01

Objectives: This study hypothesized that besides iron deficiency, intestinal parasites infection is also a determinant of anemia in schoolchildren in rural Vietnam. Methods: 400 primary schoolchildren from 20 primary schools in Tam Nong district, a poor rural area in Vietnam, were randomly selected

Expression of acid-sensing ion channels and selection of reference genes in mouse and naked mole rat.

Science.gov (United States)

Schuhmacher, Laura-Nadine; Smith, Ewan St John

2016-12-13

Acid-sensing ion channels (ASICs) are a family of ion channels comprised of six subunits encoded by four genes and they are expressed throughout the peripheral and central nervous systems. ASICs have been implicated in a wide range of physiological and pathophysiological processes: pain, breathing, synaptic plasticity and excitotoxicity. Unlike mice and humans, naked mole-rats do not perceive acid as a noxious stimulus, even though their sensory neurons express functional ASICs, likely an adaptation to living in a hypercapnic subterranean environment. Previous studies of ASIC expression in the mammalian nervous system have often not examined all subunits, or have failed to adequately quantify expression between tissues; to date there has been no attempt to determine ASIC expression in the central nervous system of the naked mole-rat. Here we perform a geNorm study to identify reliable housekeeping genes in both mouse and naked mole-rat and then use quantitative real-time PCR to estimate the relative amounts of ASIC transcripts in different tissues of both species. We identify RPL13A (ribosomal protein L13A) and CANX (calnexin), and β-ACTIN and EIF4A (eukaryotic initiation factor 4a) as being the most stably expressed housekeeping genes in mouse and naked mole-rat, respectively. In both species, ASIC3 was most highly expressed in dorsal root ganglia (DRG), and ASIC1a, ASIC2b and ASIC3 were more highly expressed across all brain regions compared to the other subunits. We also show that ASIC4, a proton-insensitive subunit of relatively unknown function, was highly expressed in all mouse tissues apart from DRG and hippocampus, but was by contrast the lowliest expressed ASIC in all naked mole-rat tissues.

Non-invasive assessment of glucocorticoid and androgen metabolite levels in cooperatively breeding Damaraland mole-rats (Fukomys damarensis).

Science.gov (United States)

Medger, Katarina; Bennett, Nigel C; Lutermann, Heike; Ganswindt, Andre

2018-05-18

Dominant females of cooperative breeding species often use aggression to suppress reproduction of subordinate females, resulting in subordinates experiencing stress-related increases in glucocorticoid levels, which may cause reproductive down-regulation. This would suggest a general pattern with higher glucocorticoid levels in subordinate compared to dominant individuals; however, the opposite was found in a number of cooperatively breeding species. Furthermore, breeding females of the cooperatively breeding Damaraland mole-rats (Fukomys damarensis) exhibit very high androgen concentrations during the wet season, presumably to support their breeding monopoly. Hormone analysis in Damaraland mole-rats have typically been measured using plasma and urine, but faecal analysis offers additional advantages especially for field studies on this species. The present study examines the suitability of Damaraland mole-rat faecal samples for determining glucocorticoid metabolite (fGCM) and androgen metabolite (fAM) concentrations using enzyme immunoassays. Using these assays, we further evaluated the effects of breeding status on fGCM and fAM concentrations in wild-caught and captive Damaraland mole-rats. Wild-caught breeding and non-breeding males and females exhibited no differences in fAM concentrations. Immunoreactive fGCM concentrations were only high in male breeders and comparatively low in non-breeders and breeding females. Concentrations of fAMs and fGCMs were similar in captive males and females, but fAM concentrations were elevated in captive compared to wild-caught individuals, which may be related to a higher reproductive activity due to removal from the breeding female. The relatively uniform fAM and fGCM concentrations found in wild-caught mole-rats may be explained by a stable colony structure during the dry season during which this study was conducted. Limited dispersal opportunities result in lower aggression and stress levels within a colony and as a result

Primary English Language Education Policy in Vietnam: Insights from Implementation

Science.gov (United States)

Nguyen, Hoa Thi Mai

2011-01-01

The introduction of English in primary education curricula is a phenomenon occurring in many non-English-speaking countries in Asia, including Vietnam. Recently, the Ministry of Education and Training (MOET) in Vietnam issued guidelines for the piloting of an English as a foreign language (EFL) primary curriculum in which English is taught as a…

Teaching the New Vietnam: It's a Country, Not a War

Science.gov (United States)

McCornac, Dennis C.

2008-01-01

Vietnam has made remarkable progress over the past two decades in its transition to a market economy resulting in numerous changes to both its social and economic institutions. It is a nation at peace focusing on economic development and integrating into the world economy. Although the tragic events in Vietnam's history cannot be forgotten, the…

Evaluation of the Epidemiological Impact of Harm Reduction Programs on HIV in Vietnam

OpenAIRE

UNAIDS; World Bank

2010-01-01

Vietnam s HIV epidemic is concentrated, both in specific behavioral sub-populations and geographic regions. The key populations at higher risk for HIV infection in Vietnam are female sex workers (FSW) and their clients; injecting drug users (IDU); and men who have sex with men (MSM). Vietnam identified harm reduction interventions for IDU and FSW as a key component of its last 5-year Natio...

Assessing potential impacts of the EVFTA on Vietnam's pharmaceutical imports from the EU: an application of SMART analysis.

Science.gov (United States)

Vu, Huong Thanh

2016-01-01

This paper by adopting the Software on Market Analysis and Restrictions on Trade assessed the ex-ante impact of tariff elimination under the European-Vietnam free trade agreement (EVFTA) on Vietnam's pharmaceutical imports from the EU based on two scenarios. The results showed that although Vietnam's tariff removal for the EU's medicines would not result in a significant increase in Vietnam's imports from the EU, Vietnam's deeper integration with ASEAN + 3 and TPP (the Trans-Pacific Partnership) nations would affect quite slightly on its imports from the EU. Therefore, the EU would be still the most important and biggest source of pharmaceuticals for Vietnam in the near future. In addition, there might be an uneven distribution in Vietnam's import increases by the EU nation, pharmaceutical group and product. The simulation results also pointed out that the EVFTA's trade creation effect would be higher than trade diversion effect and therefore the agreement would improve welfare of Vietnam. When Vietnam extends its coverage of tariff elimination to also TPP and ASEAN + 3, Vietnam's welfare would potentially increase more but Vietnam would face with the relatively high increases of pharmaceutical imports from not only the EU but also the US, Australia, South Korea, Thailand and China. Bases on these results, the paper argued that both the Vietnamese government and pharmaceutical enterprises should not neglect the EVFTA and its impacts on the pharmaceutical sector, and perceive clearly the uneven distribution of Vietnam's import changes from the EU by nation and by product to design appropriate business and investment strategy. In addition, Vietnam should take measures to diversify its European import markets to be less dependent on the traditional ones in the current context of the EU. Finally, Vietnam should promote the integration in the pharmaceutical sector with all three groups of nations, especially ASEAN and ASEAN's key partners, to reduce trade diversion

International Uranium Resources Evaluation Project (IUREP) national favourability studies: Vietnam

International Nuclear Information System (INIS)

1977-11-01

The Chaine Annamatique represents the last of the three orogenic episodes that shook Indochina and forms most of Vietnam's boundary with Laos, In south Vietnam the mountains which have a north-south trend are formed of granites, gneisses and mica schists and are inseparable from the anti-hercynian formations. Iron ore, gold, lead, copper, tin, wolfraun, bismuth and molybdenium minerals are found. Plans had been made in 1960 to prospect for uranium but no information is available on whether that work was ever done. The only evidence of occurrences of nuclear raw materials is that titaniferous sands occur in several coastal regions and that uranium was once listed as having been produced in Forth Vietnam. Although the geology of Vietnam is not very conducive to the formation and preservation of uranium deposits it is possible that because of the granite terrain and presence of other metalliferous minerals, the Speculative Potential should be stated as in category 2 i.e. from 1,000 to 10,000 tonnes uranium. (author)

A stable algorithm for calculating phase equilibria with capillarity at specified moles, volume and temperature using a dynamic model

KAUST Repository

Kou, Jisheng

2017-09-30

Capillary pressure can significantly affect the phase properties and flow of liquid-gas fluids in porous media, and thus, the phase equilibrium calculation incorporating capillary pressure is crucial to simulate such problems accurately. Recently, the phase equilibrium calculation at specified moles, volume and temperature (NVT-flash) becomes an attractive issue. In this paper, capillarity is incorporated into the phase equilibrium calculation at specified moles, volume and temperature. A dynamical model for such problem is developed for the first time by using the laws of thermodynamics and Onsager\\'s reciprocal principle. This model consists of the evolutionary equations for moles and volume, and it can characterize the evolutionary process from a non-equilibrium state to an equilibrium state in the presence of capillarity effect at specified moles, volume and temperature. The phase equilibrium equations are naturally derived. To simulate the proposed dynamical model efficiently, we adopt the convex-concave splitting of the total Helmholtz energy, and propose a thermodynamically stable numerical algorithm, which is proved to preserve the second law of thermodynamics at the discrete level. Using the thermodynamical relations, we derive a phase stability condition with capillarity effect at specified moles, volume and temperature. Moreover, we propose a stable numerical algorithm for the phase stability testing, which can provide the feasible initial conditions. The performance of the proposed methods in predicting phase properties under capillarity effect is demonstrated on various cases of pure substance and mixture systems.

Electrical Activation Studies of Silicon Implanted Aluminum Gallium Nitride with High Aluminum Mole Fraction

National Research Council Canada - National Science Library

Moore, Elizabeth A

2007-01-01

...) alloys, and represents a comprehensive analysis of the resulting material's electrical and optical properties as a function of Al mole fraction, anneal temperature, anneal time, and implantation dose...

Recent applications of nuclear medicine techniques and results in Vietnam

International Nuclear Information System (INIS)

Phan Sy An

2008-01-01

The author presented recent applications of nuclear medicine techniques and results in Vietnam. The author concentrated some valuable and helpful studies such as functional tests, myocardial perfusion scintigraphy, bone, thyroid, lung, kidney and gastrointestinal tract scintigraphy for diagnosis. The results of RIA and IRMA concerning with thyroid diseases, cancer, microalbuminuria and TSH in blood spot on paper for screening of congenital hypothyroidism in new born babies were also given. The report also mentioned results of liver cancer and palliative bone metastasis treatments in Vietnam. A new technique using gamma probe in surgery for breast cancer was presented. The author introduced some modern teleradiotherapeutic modalities such as cyberknif, gamma knife, gamma rotating systeme and linac recently installed in Vietnam. (author)

A study on the establishment of nuclear cooperative relations and future direction between Korea and Vietnam

Energy Technology Data Exchange (ETDEWEB)

Yang, M H; Kim, H S; Chung, W S; Yun, S W; Ko, H S; Lee, J K

2000-10-01

This study was carried out in order to review the cooperation with vietnam and establish and activate the cooperative relations with Vietnam. During the study, current status of use and development of nuclear energy in vietnam, were investigated including nuclear power plant and cooperative relations between two nations were also established. It was agreed through exchanges of visits of cooperation delegation; 1) exchange of visits of cooperation delegation, 2) holding of policy seminar for high level decision makers of Vietnam 3) cooperaton between KAERI/VAEC, 4) joint feasibility study for the construction of KSNP into Vietnam and technical presentation of KSNP. It is recommended that cooperaion with vietnam be implemented systematically through the long term based basic directions and integrated national strategies.

A study on the establishment of nuclear cooperative relations and future direction between Korea and Vietnam

International Nuclear Information System (INIS)

Yang, M. H.; Kim, H. S.; Chung, W. S.; Yun, S. W.; Ko, H. S.; Lee, J. K.

2000-10-01

This study was carried out in order to review the cooperation with vietnam and establish and activate the cooperative relations with Vietnam. During the study, current status of use and development of nuclear energy in vietnam, were investigated including nuclear power plant and cooperative relations between two nations were also established. It was agreed through exchanges of visits of cooperation delegation; 1) exchange of visits of cooperation delegation, 2) holding of policy seminar for high level decision makers of Vietnam 3) cooperaton between KAERI/VAEC, 4) joint feasibility study for the construction of KSNP into Vietnam and technical presentation of KSNP. It is recommended that cooperaion with vietnam be implemented systematically through the long term based basic directions and integrated national strategies

Family Wide Molecular Adaptations to Underground Life in African Mole-Rats Revealed by Phylogenomic Analysis.

Science.gov (United States)

Davies, Kalina T J; Bennett, Nigel C; Tsagkogeorga, Georgia; Rossiter, Stephen J; Faulkes, Christopher G

2015-12-01

During their evolutionary radiation, mammals have colonized diverse habitats. Arguably the subterranean niche is the most inhospitable of these, characterized by reduced oxygen, elevated carbon dioxide, absence of light, scarcity of food, and a substrate that is energetically costly to burrow through. Of all lineages to have transitioned to a subterranean niche, African mole-rats are one of the most successful. Much of their ecological success can be attributed to a diet of plant storage organs, which has allowed them to colonize climatically varied habitats across sub-Saharan Africa, and has probably contributed to the evolution of their diverse social systems. Yet despite their many remarkable phenotypic specializations, little is known about molecular adaptations underlying these traits. To address this, we sequenced the transcriptomes of seven mole-rat taxa, including three solitary species, and combined new sequences with existing genomic data sets. Alignments of more than 13,000 protein-coding genes encompassed, for the first time, all six genera and the full spectrum of ecological and social variation in the clade. We detected positive selection within the mole-rat clade and along ancestral branches in approximately 700 genes including loci associated with tumorigenesis, aging, morphological development, and sociality. By combining these results with gene ontology annotation and protein-protein networks, we identified several clusters of functionally related genes. This family wide analysis of molecular evolution in mole-rats has identified a suite of positively selected genes, deepening our understanding of the extreme phenotypic traits exhibited by this group. © The Author 2015. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

When History Talks Back: Teaching Nonfiction Literature of the Vietnam War.

Science.gov (United States)

Johannessen, Larry R.

2002-01-01

Presents student responses to nonfiction literature of the Vietnam War. Describes reasons for teaching the nonfiction literature of the Vietnam War. Concludes that this literature is accessible and engaging to students, and it deals with issues that speak to students in powerful ways. (SG)

Functional neurokinin and NMDA receptor activity in an animal naturally lacking substance P: the naked mole-rat.

Directory of Open Access Journals (Sweden)

Antje Brand

Full Text Available Naked mole-rats are extremely unusual among mammals in that their cutaneous C-fibers lack the neuropeptide Substance P (SP. In other mammals, SP plays an important role in nociception: it is released from C-fibers onto spinal neurons where it facilitates NMDA receptor activity and causes sensitization that can last for minutes, hours or days. In the present study, we tested the effects of intrathecal application of: 1 SP, 2 an SP antagonist (GR-82334, and 3 an NMDA antagonist (APV on heat-evoked foot withdrawal. In the naked mole-rat, at a high enough concentration, application of SP caused a large, immediate, and long-lasting sensitization of foot withdrawal latency that was transiently reversed by application of either antagonist. However, neither SP nor NMDA antagonists had an effect when administered alone to naïve animals. In contrast, both antagonists induced an increase in basal withdrawal latency in mice. These results indicate that spinal neurons in naked mole-rats have functional SP and NMDA receptors, but that these receptors do not participate in heat-evoked foot withdrawal unless SP is experimentally introduced. We propose that the natural lack of SP in naked mole-rat C-fibers may have resulted during adaptation to living in a chronically high carbon dioxide, high ammonia environment that, in other mammals, would stimulate C-fibers and evoke nocifensive behavior.

Functional neurokinin and NMDA receptor activity in an animal naturally lacking substance P: the naked mole-rat.

Science.gov (United States)

Brand, Antje; Smith, Ewan St J; Lewin, Gary R; Park, Thomas J

2010-12-21

Naked mole-rats are extremely unusual among mammals in that their cutaneous C-fibers lack the neuropeptide Substance P (SP). In other mammals, SP plays an important role in nociception: it is released from C-fibers onto spinal neurons where it facilitates NMDA receptor activity and causes sensitization that can last for minutes, hours or days. In the present study, we tested the effects of intrathecal application of: 1) SP, 2) an SP antagonist (GR-82334), and 3) an NMDA antagonist (APV) on heat-evoked foot withdrawal. In the naked mole-rat, at a high enough concentration, application of SP caused a large, immediate, and long-lasting sensitization of foot withdrawal latency that was transiently reversed by application of either antagonist. However, neither SP nor NMDA antagonists had an effect when administered alone to naïve animals. In contrast, both antagonists induced an increase in basal withdrawal latency in mice. These results indicate that spinal neurons in naked mole-rats have functional SP and NMDA receptors, but that these receptors do not participate in heat-evoked foot withdrawal unless SP is experimentally introduced. We propose that the natural lack of SP in naked mole-rat C-fibers may have resulted during adaptation to living in a chronically high carbon dioxide, high ammonia environment that, in other mammals, would stimulate C-fibers and evoke nocifensive behavior.

Lessons for Hospital Autonomy : Implementation in Vietnam from International Experience

OpenAIRE

Vietnam Ministry of Health; Health Strategy and Policy Institute; World Bank; World Health Organization

2011-01-01

The Government of Vietnam sees hospital autonomy policy as important and consistent with current development trends in Vietnam. It is based on government policies as laid out in government Decree on financial autonomy of revenue-generating public service entities; and to 2006, it is replaced by decree on professional, organizational, human resource management and financial autonomy of reve...

Pharmacy Education in Vietnam

Science.gov (United States)

Bedouch, Pierrick; Nguyen, Thi-Hoai; Nguyen, Thi-Lien-Huong; Hoang, Thi-Kim-Huyen; Calop, Jean; Allenet, Benoît

2013-01-01

Pharmacy education programs in Vietnam are complex and offer various career pathways. All include theory and laboratory modules in general, foundation, and pharmaceutical knowledge; placements in health facilities; and a final examination. The various pharmacy degree programs allow specialization in 1 or more of 5 main fields: (1) drug management and supply, (2) drug development and production, (3) pharmacology and clinical pharmacy, (4) traditional medicine and pharmacognosy, and (5) drug quality control, which are offered as main specialization options during the reformed undergraduate and postgraduate programs. However, pharmacy education in Vietnam in general remains product oriented and clinical pharmacy training has not received adequate attention. Only students who have obtained the bachelor of pharmacy degree, which requires a minimum of 5 years of study, are considered as fully qualified pharmacists. In contrast, an elementary diploma in pharmacy awarded after 1 year of pharmacy study permits entry into more junior pharmacy positions. Since the 2000s, there has been a surge in the number and types of schools offering pharmacy qualifications at various levels. PMID:23966717

Influence of spatial environment on maze learning in an African mole-rat

CSIR Research Space (South Africa)

Du Toit, L

2012-05-01

Full Text Available -1 Anim Cogn DOI 10.1007/s10071-012-0503-0 Influence of spatial environment on maze learning in an African mole-rat Lydia du Toit ? Nigel C. Bennett ? Alecia Nickless ? Martin J. Whiting L. du Toit , A. Nickless , M. J. Whiting (email) School...

case of natural queen succession in a captive colony of naked mole ...

African Journals Online (AJOL)

Naked mole-rats occur in large colonies where usually a single queen monopolizes reproduction. Queen succession occurs from within usually as a result of aggressive encounters with subordinate females that queue for reproductive succession following colony instability, which inevitably results in death of either the ...

Geographic isolation and elevational gradients promote diversification in an endemic shrew on Sulawesi.

Science.gov (United States)

Eldridge, Ryan A; Achmadi, Anang S; Giarla, Thomas C; Rowe, Kevin C; Esselstyn, Jacob A

2018-01-01

Phylogeographic research on endemic primates and amphibians inhabiting the Indonesian island of Sulawesi revealed the existence of seven areas of endemism (AoEs). Here, we use phylogenetic and population genetic analyses of one mitochondrial gene and 15 nuclear loci to assess geographic patterns of genetic partitioning in a shrew (Crocidura elongata) that is endemic to Sulawesi, but occurs across the island. We uncover substantial genetic diversity in this species both between and within AoEs, but we also identify close relationships between populations residing in different AoEs. One of the earliest divergences within C. elongata distinguishes a high-elevation clade from low-elevation clades. In addition, on one mountain, we observe three distinct genetic groups from low, middle, and high elevations, suggesting divergence along a single elevational gradient. In general, our results show that C. elongata, like several other Sulawesi endemic taxa, harbors extensive genetic diversity. This diversity is structured in part by known AoE boundaries, but also by elevational gradients and geographic isolation within AoEs. Copyright © 2017 Elsevier Inc. All rights reserved.

A Mole in the Sole: Case Report on Eccrine Poroma

Directory of Open Access Journals (Sweden)

Dr. Arnab Ghosh

2007-01-01

Full Text Available Eccrine poroma is a benign tumor which arises from the intraepidermal portion of the eccrine sweat glands. 81 year old diabetic grandma worried about her persistently uncontrolled blood sugar owing to a painless mole in the sole of right foot for 2 years. Excisional biopsy revealed a sweat duct benign eccrine poroma. A relationship with diabetes mellitus could not be clearly established in this case.

78 FR 11221 - Frozen Warmwater Shrimp From China, Ecuador, India, Indonesia, Malaysia, Thailand, and Vietnam

Science.gov (United States)

2013-02-15

... Shrimp From China, Ecuador, India, Indonesia, Malaysia, Thailand, and Vietnam Determination On the basis... injured by reason of imports from China, Ecuador, India, Indonesia, Malaysia, Thailand, and Vietnam of... China, Ecuador, India, Indonesia, Malaysia, Thailand, and Vietnam.\\2\\ \\1\\ The record is defined in sec...

Greening Food Processing Industry in Vietnam: Putting Industrial Ecology to Work

NARCIS (Netherlands)

Tran Thi My Dieu,

2003-01-01

The significant contribution to Vietnam's gross domestic product over the years give evidence of the important role of food processing industry in the economic and industrial development of the country. This is even more relevant from now onwards, as it is Vietnam's development strategy to become

"Causal" Communication: Media Portrayals and Public Attributions for Vietnam Veterans' Problems.

Science.gov (United States)

Griffin, Robert J.; Sen, Shaikat

A study of "causal" communication, the communication of attribution-related information, investigated the relationship of exposure to mass media (especially film) depictions of Vietnam veterans to perceived causes for the problems facing a number of Vietnam veterans. The study further extends attribution theory to social interaction and…

78 FR 10210 - Utility Scale Wind Towers From China and Vietnam

Science.gov (United States)

2013-02-13

... wind towers. Background The Commission instituted these investigations effective December 29, 2011...)] Utility Scale Wind Towers From China and Vietnam Determinations On the basis of the record \\1\\ developed... with material injury by reason of imports of utility scale wind towers from China and Vietnam, provided...

Female breast cancer in Vietnam: a comparison across Asian specific regions.

Science.gov (United States)

Trieu, Phuong Dung Yun; Mello-Thoms, Claudia; Brennan, Patrick C

2015-09-01

Breast cancer is one of the most commonly diagnosed malignancies and the leading cause of cancer death of women over the world. A large number of females with breast cancer in Vietnam and other Southeast Asian (SEA) countries present at an early age with more aggressive tumors compared with women in Australia. Despite experiencing a low incidence rate, the increasing incidence rate among SEA countries exceeds that of the Westernized world. Changes in reproductive factors, environmental exposures, and lifestyle are the possible causes of this trend. However, limited evidence shows that these factors are associated with breast cancer in the Vietnamese population. Breast cancer incidence rates within Vietnam are not uniform and appear to be dependent on geographic location. Findings from this review have important implications for breast cancer control and treatment in Vietnam. A good understanding of the morphology of the breast and the type and nature of breast cancers presenting in Vietnam is required to facilitate the introduction of an effective national breast screening program.

VIETNAM AND FOREIGN DIRECT INVESTMENT: POTENTIALS ANDCHALLENGES ON THE LABOR MARKET

Directory of Open Access Journals (Sweden)

Nathalie Homlong

2013-07-01

Full Text Available For several years Vietnam has been receiving attention as an attractive businesslocation for foreign companies. But in spite of overall positive economicdevelopments, foreign companies in Vietnam also experience challenges, e.g.connected to bureaucracy and corruption. Another issue that is of crucialimportance for foreign companies in foreign markets are the conditions on thelabor market. This paper investigates questions about the potentials andchallenges for foreign companies on the Vietnamese labor market, and of howattractive Vietnam’s labor market is compared to India and China.Educationlevels, productivity, wage levels, and number of strikes are among theindicators that are used to compare the attractiveness of Vietnam’s labor market tothe labor markets of China and India. Furthermore the results of almost 30interviews conducted withcompanies from Austria, Germany and Switzerland ontheir experiences with doing business in Vietnam are used to shed light on thestrengths and weaknesses of the labor market in Vietnam.

The Vietnam Drug User Returns. Final Report. Special Action Office Monograph, Series A, Number 2, May 1974.

Science.gov (United States)

Robins, Lee N.

This report, based upon case records and follow-up interviews with 965 U.S. Servicemen returning from Vietnam investigates: (1) the availability and utilization of narcotics, marihuana and alcohol in Vietnam; (2) the psychosocial and demographic predictors of pre- and post-Vietnam narcotic use; and (3) the post-Vietnam adjustment difficulties of…

Sun-Earth System Interaction studies over Vietnam: an international cooperative project

Directory of Open Access Journals (Sweden)

C. Amory-Mazaudier

2006-12-01

Full Text Available During many past decades, scientists from various countries have studied separately the atmospheric motions in the lower atmosphere, in the Earth's magnetic field, in the magnetospheric currents, etc. All of these separate studies lead today to the global study of the Sun and Earth connections, and as a consequence, new scientific programs (IHY- International Heliophysical Year, CAWSES- Climate and Weather in the Sun-Earth System are defined, in order to assume this new challenge. In the past, many scientists did not have the possibility to collect data at the same time in the various latitude and longitude sectors. Now, with the progress of geophysical sciences in many developing countries, it is possible to have access to worldwide data sets. This paper presents the particularities of geophysical parameters measured by the Vietnamese instrument networks. It introduces a cooperative Vietnamese-IGRGEA (International Geophysical Research Group Europe Africa project, and presents, for the first time, to the international community, the geophysical context of Vietnam. Concerning the ionosphere: since 1963, during four solar cycles, the ionosonde at Phu Thuy (North Vietnam was operating. The Phu Thuy data exhibits the common features for the ionospheric parameters, previously observed in other longitude and latitude sectors. The critical frequencies of the E, F1 and F2 ionospheric layers follow the variation of the sunspot cycle. F2 and E critical frequencies also exhibit an annual variation. The first maps of TEC made with data from GPS receivers recently installed in Vietnam illustrate the regional equatorial pattern, i.e. two maxima of electronic density at 15° N and 15° S from the magnetic equator and a trough of density at the magnetic equator. These features illustrate the equatorial fountain effect. Concerning the Earth's magnetic field: a strong amplitude of the equatorial electrojet was first observed by the CHAMP satellite at the height

Neurology in the Vietnam War.

Science.gov (United States)

Gunderson, Carl H; Daroff, Robert B

2016-01-01

Between December 1965 and December 1971, the United States maintained armed forces in Vietnam never less than 180,000 men and women in support of the war. At one time, this commitment exceeded half a million soldiers, sailors, and airmen from both the United States and its allies. Such forces required an extensive medical presence, including 19 neurologists. All but two of the neurologists had been drafted for a 2-year tour of duty after deferment for residency training. They were assigned to Vietnam for one of those 2 years in two Army Medical Units and one Air Force facility providing neurological care for American and allied forces, as well as many civilians. Their practice included exposure to unfamiliar disorders including cerebral malaria, Japanese B encephalitis, sleep deprivation seizures, and toxic encephalitis caused by injection or inhalation of C-4 explosive. They and neurologists at facilities in the United States published studies on all of these entities both during and after the war. These publications spawned the Defense and Veterans Head Injury Study, which was conceived during the Korean War and continues today as the Defense and Veterans Head Injury Center. It initially focused on post-traumatic epilepsy and later on all effects of brain injury. The Agent Orange controversy arose after the war; during the war, it was not perceived as a threat by medical personnel. Although soldiers in previous wars had developed serious psychological impairments, post-traumatic stress disorder was formally recognized in the servicemen returning from Vietnam. © 2016 S. Karger AG, Basel.

Vietnam : A Handwashing Behavior Change Journey for the Caretakers’ Program

OpenAIRE

World Bank

2011-01-01

The Vietnam Handwashing Initiative (HWI) was launched in January 2006 by the Ministry of Health (MoH) with funds from the Danish Embassy in Vietnam and technical assistance from the Water and Sanitation Program (WSP). This learning note documents the development process of the caretakers' program with a focus on how it was designed, implemented, and monitored. Lessons learned and challenge...

The coal mining industry in Vietnam and its challenges; Steinkohlenbergbau in Vietnam und seine Herausforderungen

Energy Technology Data Exchange (ETDEWEB)

Martens, Per Nicolai; Pateiro Fernandez, Jose B.; Ahmad, Shakeel [RWTH Aachen (Germany). Inst. fuer Bergbaukunde I; Cramer, Thomas; Deissmann, Guido [Brenk Systemplanung GmbH, Aachen (Germany); Fuchsschwanz, Marcus [RWTH Aachen (Germany). Lehrstuhl fuer Geotechnik

2010-04-15

The province of Quang Ninh in the north of Vietnam is the most important coal mining region in the country. The NBCC (Nui Beo Coal Company) operates several open-cast mines. Large quantities of overburden have to be removed and dumped in the immediate environment. The creation of these heaps up to 300 m high is accompanied by many environmental problems. In particular ground and surface waters are contaminated by ''acid mine drainage''. Furthermore, large emissions chiefly in the form of dust occur as a result of the working and dumping depending on the season. In addition the stability of the heaps is sometimes greatly endangered. In the German-Vietnamese Research Association Mining and Environment in Vietnam (RAME) the aspects of coal mining with an effect on the environment are dealt with in various sub-associations and protective measures worked out jointly. (orig.)

The Vietnam Vet's Battle--Unemployment

Science.gov (United States)

Werner, Wayne E.; Radcliff, Jo Ann

1973-01-01

The purpose of this article was to survey the employment situation of returning Vietnam veterans. The picture appears to be one of frustration. There are a number of programs available but a communications gap seems to exist between the programs and the veterans. (Author)

Evolution of highly pathogenic H5N1 avian influenza viruses in Vietnam between 2001 and 2007.

Directory of Open Access Journals (Sweden)

Xiu-Feng Wan

Full Text Available Highly pathogenic avian influenza (HPAI H5N1 viruses have caused dramatic economic losses to the poultry industry of Vietnam and continue to pose a serious threat to public health. As of June 2008, Vietnam had reported nearly one third of worldwide laboratory confirmed human H5N1 infections. To better understand the emergence, spread and evolution of H5N1 in Vietnam we studied over 300 H5N1 avian influenza viruses isolated from Vietnam since their first detection in 2001. Our phylogenetic analyses indicated that six genetically distinct H5N1 viruses were introduced into Vietnam during the past seven years. The H5N1 lineage that evolved following the introduction in 2003 of the A/duck/Hong Kong/821/2002-like viruses, with clade 1 hemagglutinin (HA, continued to predominate in southern Vietnam as of May 2007. A virus with a clade 2.3.4 HA newly introduced into northern Vietnam in 2007, reassorted with pre-existing clade 1 viruses, resulting in the emergence of novel genotypes with neuraminidase (NA and/or internal gene segments from clade 1 viruses. A total of nine distinct genotypes have been present in Vietnam since 2001, including five that were circulating in 2007. At least four of these genotypes appear to have originated in Vietnam and represent novel H5N1 viruses not reported elsewhere. Geographic and temporal analyses of H5N1 infection dynamics in poultry suggest that the majority of viruses containing new genes were first detected in northern Vietnam and subsequently spread to southern Vietnam after reassorting with pre-existing local viruses in northern Vietnam. Although the routes of entry and spread of H5N1 in Vietnam remain speculative, enhanced poultry import controls and virologic surveillance efforts may help curb the entry and spread of new HPAI viral genes.

Multidimensional MRI-CT atlas of the naked mole-rat brain (Heterocephalus glaber).

Science.gov (United States)

Seki, Fumiko; Hikishima, Keigo; Nambu, Sanae; Okanoya, Kazuo; Okano, Hirotaka J; Sasaki, Erika; Miura, Kyoko; Okano, Hideyuki

2013-01-01

Naked mole-rats have a variety of distinctive features such as the organization of a hierarchical society (known as eusociality), extraordinary longevity, and cancer resistance; thus, it would be worthwhile investigating these animals in detail. One important task is the preparation of a brain atlas database that provide comprehensive information containing multidimensional data with various image contrasts, which can be achievable using a magnetic resonance imaging (MRI). Advanced MRI techniques such as diffusion tensor imaging (DTI), which generates high contrast images of fiber structures, can characterize unique morphological properties in addition to conventional MRI. To obtain high spatial resolution images, MR histology, DTI, and X-ray computed tomography were performed on the fixed adult brain. Skull and brain structures were segmented as well as reconstructed in stereotaxic coordinates. Data were also acquired for the neonatal brain to allow developmental changes to be observed. Moreover, in vivo imaging of naked mole-rats was established as an evaluation tool of live animals. The data obtained comprised three-dimensional (3D) images with high tissue contrast as well as stereotaxic coordinates. Developmental differences in the visual system were highlighted in particular by DTI. Although it was difficult to delineate optic nerves in the mature adult brain, parts of them could be distinguished in the immature neonatal brain. From observation of cortical thickness, possibility of high somatosensory system development replaced to the visual system was indicated. 3D visualization of brain structures in the atlas as well as the establishment of in vivo imaging would promote neuroimaging researches towards detection of novel characteristics of eusocial naked mole-rats.

Fos expression in the suprachiasmatic nucleus in response to light stimulation in a solitary and social species of African mole-rat (family Bathyergidae).

Science.gov (United States)

Oosthuizen, M K; Bennett, N C; Cooper, H M

2005-01-01

Mole-rats are strictly subterranean rodents that are rarely exposed to environmental light. They are well adapted to their environment and have reduced eyes and a severely regressed visual system. It has been shown, however, that mole-rats do exhibit endogenous circadian rhythms that can be entrained, suggesting an intact and functional circadian system. To determine whether light is the entraining agent in these animals, Fos expression in response to light pulses at different circadian times was investigated to obtain phase response curves. Light is integrated effectively in the suprachiasmatic nucleus of the Cape mole-rat (Georychus capensis), and Fos expression is gated according to the phase of the circadian clock. The Fos response in the Cape mole-rat was comparable to that of aboveground rodents. In contrast, the highveld mole-rat (Cryptomys hottentotus pretoriae) was less sensitive to light and did not show a selective Fos response according to the phase of the circadian cycle. Social species appear to be less sensitive to light than their solitary counterparts, which compares well with results from locomotor activity studies.

Mola hidatiforme e doença trofoblástica gestacional Hydatidiform mole and gestational trophoblastic disease

Directory of Open Access Journals (Sweden)

Jurandyr Moreira de Andrade

2009-02-01

Full Text Available A mola hidatiforme é uma complicação relativamente infrequente da gravidez, mas com potencial para evolução para formas que necessitam de tratamento sistêmico e podem ser ameaçadoras da vida. Sob a denominação de mola hidatiforme há duas entidades histopatológicas e clínicas: a mola parcial e a completa. As diferenças entre estas duas formas são importantes, devido ao risco de evolução para formas persistentes, ou seja, mais alto para as completas. O diagnóstico da mola hidatiforme, seu tratamento e seguimento após o tratamento inicial sofreram alterações importantes nos últimos anos. O número de pacientes assintomáticas tem aumentado devido ao emprego de ultrassonografia no início da gravidez. Para a resolução da mola hidatiforme é necessário evitar o emprego de medicamentos que induzam contrações uterinas e usar a vácuo-aspiração. Deve ser prescrito o método contraceptivo hormonal logo após o esvaziamento da mola. O seguimento é baseado nas dosagens seriadas semanais de gonadotrofinas coriônicas. É importante que o método empregado detecte todas as formas das gonadotrofinas coriônicas (molécula intacta, hiperglicosilada, subunidade β livre e fragmento central da subunidade β.The hydatiform mole is a relatively rare pregnancy complication, but with potential to evolve to forms which need systemic treatment and can be a threat to life. There are two histopathological and clinical entities under the name of hydatiform mole: the partial and the complete mole. The differences between the two forms are important due to risk of evolution to persistent forms, which is higher for the complete moles. The diagnosis, treatment and follow-up of hydatiform mole have been under important changes in the last years. The number of asymptomatic patients has increased, due to the use of ultrasonography at the onset of pregnancy. The use of medication that induces uterine contractions must be avoided, and vacuum

77 FR 9701 - Steel Wire Garment Hangers From Taiwan And Vietnam

Science.gov (United States)

2012-02-17

...)] Steel Wire Garment Hangers From Taiwan And Vietnam Determinations On the basis of the record \\1...)) (the Act), that there is a reasonable indication that an industry in the United States is materially injured by reason of imports from Taiwan and Vietnam of steel wire garment hangers, provided for in...

Digital dissection of the masticatory muscles of the naked mole-rat, Heterocephalus glaber (Mammalia, Rodentia

Directory of Open Access Journals (Sweden)

Philip G. Cox

2014-06-01

Full Text Available The naked mole-rat, Heterocephalus glaber, of the family Bathyergidae is a subterranean rodent that feeds on underground roots and tubers and digs extensive tunnel systems with its incisors. It is a highly unusual mammal with regard to its social structure, longevity, pain insensitivity and cancer resistance, all of which have made it the subject of a great deal of research in recent years. Yet, much of the basic anatomy of this species remains undocumented. In this paper, we describe the morphology of the jaw-closing musculature of the naked mole-rat, as revealed by contrast-enhanced micro-computed tomography. This technique uses an iodine stain to enable the imaging of soft tissues with microCT. The iodine-enhanced scans were used to create 3D reconstructions of the naked mole-rat masticatory muscles from which muscle masses were calculated. The jaw-closing musculature of Heterocephalus glaber is relatively very large compared to other rodents and is dominated by the superficial masseter, the deep masseter and the temporalis. The temporalis in particular is large for a rodent, covering the entirety of the braincase and much of the rear part of the orbit. The morphology of the masseter complex described here differs from two other published descriptions of bathyergid masticatory muscles, but is more similar to the arrangement seen in other rodent families. The zygomaticomandibularis (ZM muscle does not protrude through the infraorbital foramen on to the rostrum and thus the naked mole-rat should be considered protrogomorphous rather than hystricomorphous, and the morphology is consistent with secondarily lost hystricomorphy as has been previously suggested for Bathyergidae. Overall, the morphology of the masticatory musculature indicates a species with a high bite force and a wide gape–both important adaptations for a life dominated by digging with the incisors.

"Never Forget the Sacrifice:" A Visit to Chu Van An High School in Hanoi, Vietnam.

Science.gov (United States)

Berman, David M.

1995-01-01

Reports on a 1993 study tour of Vietnam by educators. Discusses the role of a secondary school during the struggle against French colonialism and the U.S.-Vietnam War. Argues that educators must acknowledge the humanity of the Vietnamese as the first step in designing Vietnam-related social studies curriculum. (CFR)

Invasive Plant Species in the National Parks of Vietnam

OpenAIRE

Bernard Dell; Pham Quang Thu; Dang Thanh Tan

2012-01-01

The impact of invasive plant species in national parks and forests in Vietnam is undocumented and management plans have yet to be developed. Ten national parks, ranging from uncut to degraded forests located throughout Vietnam, were surveyed for invasive plant species. Transects were set up along roads, trails where local people access park areas, and also tracks through natural forest. Of 134 exotic weeds, 25 were classified as invasive species and the number of invasive species ranged from ...

Mental health priorities in Vietnam: a mixed-methods analysis

Directory of Open Access Journals (Sweden)

Niemi Maria

2010-09-01

Full Text Available Abstract Background The Mental Health Country Profile is a tool that was generated by the International Mental Health Policy and Services Project to inform policy makers, professionals and other key stakeholders about important issues which need to be considered in mental health policy development. The Mental Health Country Profile contains four domains, which include the mental health context, resources, provision and outcomes. We have aimed to generate a Mental Health Country Profile for Vietnam, in order to highlight the strengths and weaknesses of the Vietnamese mental health situation, in order to inform future reform efforts and decision-making. Methods This study used snowball sampling to identify informants for generating a Mental Health Country Profile for Vietnam, and the data gathering was done through semi-structured interviews and collection of relevant reports and documents. The material from the interviews and documents was analysed according to qualitative content analysis. Results Marked strengths of the Vietnam mental health system are the aims to move toward community management and detection of mental illness, and the active involvement of several multilateral organizations and NGOs. However, there are a number of shortages still found, including the lack of treatment interventions apart from medications, the high proportion of treatments to be paid out-of-pocket, prominence of large tertiary psychiatric hospitals, and a lack of preventative measures or mental health information to the public. Conclusions At the end of this decade, mental health care in Vietnam is still characterised by unclear policy and poor critical mass especially within the governmental sector. This initial attempt to map the mental health situation of Vietnam suffers from a number of limitations and should be seen as a first step towards a comprehensive profile.

Public Relations in enhancing brand values: case study Virgin Atlantic and Vietnam Airlines

OpenAIRE

Tran Viet, Thang

2014-01-01

The ultimate purpose of this dissertation is to evaluate the Public Relations (PR) activities of Vietnam Airlines and give the airline some recommendations to improve its PR performance. In order to achieve this purpose, there are three issues needed to be solved: 1) how PR helps to enhance brand personality and brand values 2) the differences in PR activities between Vietnam Airlines and Virgin Atlantic and 3) what approaches Vietnam Airlines should implement to improve its PR performance. ...

Naked mole-rat acid-sensing ion channel 3 forms nonfunctional homomers, but functional heteromers.

Science.gov (United States)

Schuhmacher, Laura-Nadine; Callejo, Gerard; Srivats, Shyam; Smith, Ewan St John

2018-02-02

Acid-sensing ion channels (ASICs) form both homotrimeric and heterotrimeric ion channels that are activated by extracellular protons and are involved in a wide range of physiological and pathophysiological processes, including pain and anxiety. ASIC proteins can form both homotrimeric and heterotrimeric ion channels. The ASIC3 subunit has been shown to be of particular importance in the peripheral nervous system with pharmacological and genetic manipulations demonstrating a role in pain. Naked mole-rats, despite having functional ASICs, are insensitive to acid as a noxious stimulus and show diminished avoidance of acidic fumes, ammonia, and carbon dioxide. Here we cloned naked mole-rat ASIC3 (nmrASIC3) and used a cell-surface biotinylation assay to demonstrate that it traffics to the plasma membrane, but using whole-cell patch clamp electrophysiology we observed that nmrASIC3 is insensitive to both protons and the non-proton ASIC3 agonist 2-guanidine-4-methylquinazoline. However, in line with previous reports of ASIC3 mRNA expression in dorsal root ganglia neurons, we found that the ASIC3 antagonist APETx2 reversibly inhibits ASIC-like currents in naked mole-rat dorsal root ganglia neurons. We further show that like the proton-insensitive ASIC2b and ASIC4, nmrASIC3 forms functional, proton-sensitive heteromers with other ASIC subunits. An amino acid alignment of ASIC3s between 9 relevant rodent species and human identified unique sequence differences that might underlie the proton insensitivity of nmrASIC3. However, introducing nmrASIC3 differences into rat ASIC3 (rASIC3) produced only minor differences in channel function, and replacing the nmrASIC3 sequence with that of rASIC3 did not produce a proton-sensitive ion channel. Our observation that nmrASIC3 forms nonfunctional homomers may reflect a further adaptation of the naked mole-rat to living in an environment with high-carbon dioxide levels. © 2018 by The American Society for Biochemistry and Molecular

41st Vietnam National Conference on Theoretical Physics

International Nuclear Information System (INIS)

2017-01-01

Preface The 41 st Vietnam National Conference on Theoretical Physics (NCTP-41) was held during 1-4 August 2016 in Nha Trang, Vietnam. The NCTP-41 was organized by the Institute of Physics, Vietnam Academy of Science and Technology (IOP-VAST) under the support of the Vietnamese Theoretical Physics Society (VTPS). This meeting belongs to a series of annual theoretical physics conferences that started in 1976. The conference has covered a wide range of theoretical physics topics from 4 major fields: • Particle, nuclear and astro- physics, • Molecular physics, quantum optics and quantum computation, • Condensed matter physics, • Soft matter, biological and interdisciplinary physics. 115 participants have participated in the conference. 2 invited talks, 22 oral and 75 poster contributions were presented. This volume contains selected papers contributed by the participants. Editors of the NCTP-41 Proceedings Trinh Xuan Hoang, Hoang Anh Tuan and Vu Ngoc Tuoc Information about Organizer, Sponsor, Honorary Chair and Chair and also lists of committees and participants are available in the PDF (paper)

Course of Posttraumatic Stress Disorder 40 Years After the Vietnam War: Findings From the National Vietnam Veterans Longitudinal Study.

Science.gov (United States)

Marmar, Charles R; Schlenger, William; Henn-Haase, Clare; Qian, Meng; Purchia, Emily; Li, Meng; Corry, Nida; Williams, Christianna S; Ho, Chia-Lin; Horesh, Danny; Karstoft, Karen-Inge; Shalev, Arieh; Kulka, Richard A

2015-09-01

The long-term course of readjustment problems in military personnel has not been evaluated in a nationally representative sample. The National Vietnam Veterans Longitudinal Study (NVVLS) is a congressionally mandated assessment of Vietnam veterans who underwent previous assessment in the National Vietnam Veterans Readjustment Study (NVVRS). To determine the prevalence, course, and comorbidities of war-zone posttraumatic stress disorder (PTSD) across a 25-year interval. The NVVLS survey consisted of a self-report health questionnaire (n = 1409), a computer-assisted telephone survey health interview (n = 1279), and a telephone clinical interview (n = 400) in a representative national sample of veterans who served in the Vietnam theater of operations (theater veterans) from July 3, 2012, through May 17, 2013. Of 2348 NVVRS participants, 1920 were alive at the outset of the NVVLS, and 81 died during recruitment; 1450 of the remaining 1839 (78.8%) participated in at least 1 NVVLS study phase. Data analysis was performed from May 18, 2013, through January 9, 2015, with further analyses continued through April 13, 2015. Study instruments included the Mississippi Scale for Combat-Related PTSD, PTSD Checklist for DSM-IV supplemented with PTSD Checklist for DSM-5 items (PCL-5+), Clinician-Administered PTSD Scale for DSM-5 (CAPS-5), and Structured Clinical Interview for DSM-IV, Nonpatient Version. Among male theater veterans, we estimated a prevalence (95% CI) of 4.5% (1.7%-7.3%) based on CAPS-5 criteria for a current PTSD diagnosis; 10.8% (6.5%-15.1%) based on CAPS-5 full plus subthreshold PTSD; and 11.2% (8.3%-14.2%) based on PCL-5+ criteria for current war-zone PTSD. Among female veterans, estimates were 6.1% (1.8%-10.3%), 8.7% (3.8%-13.6%), and 6.6% (3.5%-9.6%), respectively. The PCL-5+ prevalence (95% CI) of current non-war-zone PTSD was 4.6% (2.6%-6.6%) in male and 5.1% (2.3%-8.0%) in female theater veterans. Comorbid major depression occurred in 36.7% (95% CI, 6

Assessing filtering of mountaintop CO2 mole fractions for application to inverse models of biosphere-atmosphere carbon exchange

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S. L. Heck

2012-02-01

Full Text Available There is a widely recognized need to improve our understanding of biosphere-atmosphere carbon exchanges in areas of complex terrain including the United States Mountain West. CO2 fluxes over mountainous terrain are often difficult to measure due to unusual and complicated influences associated with atmospheric transport. Consequently, deriving regional fluxes in mountain regions with carbon cycle inversion of atmospheric CO2 mole fraction is sensitive to filtering of observations to those that can be represented at the transport model resolution. Using five years of CO2 mole fraction observations from the Regional Atmospheric Continuous CO2 Network in the Rocky Mountains (Rocky RACCOON, five statistical filters are used to investigate a range of approaches for identifying regionally representative CO2 mole fractions. Test results from three filters indicate that subsets based on short-term variance and local CO2 gradients across tower inlet heights retain nine-tenths of the total observations and are able to define representative diel variability and seasonal cycles even for difficult-to-model sites where the influence of local fluxes is much larger than regional mole fraction variations. Test results from two other filters that consider measurements from previous and following days using spline fitting or sliding windows are overly selective. Case study examples showed that these windowing-filters rejected measurements representing synoptic changes in CO2, which suggests that they are not well suited to filtering continental CO2 measurements. We present a novel CO2 lapse rate filter that uses CO2 differences between levels in the model atmosphere to select subsets of site measurements that are representative on model scales. Our new filtering techniques provide guidance for novel approaches to assimilating mountain-top CO2 mole fractions in carbon cycle inverse models.

Effect of Al mole fraction on structural and electrical properties of AlxGa1-xN/GaN heterostructures grown by plasma-assisted molecular beam epitaxy

International Nuclear Information System (INIS)

Hussein, A. SH.; Hassan, Z.; Thahab, S.M.; Ng, S.S.; Hassan, H. Abu; Chin, C.W.

2011-01-01

The effect of Al mole fractions on the structural and electrical properties of Al x Ga 1-x N/GaN thin films grown by plasma-assisted molecular beam epitaxy (PA-MBE) on Si (1 1 1) substrates has been investigated by X-ray diffraction (XRD), scanning electron microscopy (SEM), atomic force microscopy (AFM), and current-voltage (I-V) measurements. X-ray results revealed that the AlGaN/GaN/AlN was epitaxially grown on Si substrate. By applying Vegard's law, the Al mole fractions of Al x Ga 1-x N samples were found to be 0.11, 0.24, 0.30 and 0.43, respectively. The structural and morphology results indicated that there is a relatively larger tensile strain for the sample with the smallest Al mole fraction; while a smaller compressive strain and larger grain size appear with Al mole fraction equal to 0.30. The strain gets relaxed with the highest Al mole fraction sample. Finally, the linear relationship between the barrier height and Al mole fraction was obtained.

Gis-approach for variability assessment of soil electric conductivity under pedoturbation activity of mole rat (Spalax microphthalmus

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T. М. Konovalova

2010-06-01

Full Text Available The results of the investigation of the impact of the mole rat’s activity on soil electric conductivity have been presented. GIS-technology have been shown to be effective for assessment of the pedoturbation activity effect on the soil surface heterogeneity formation. Method of the one-dimension spatial coordinated array transformation into matrix form has been proposed for following multidimension statistic analysis application. The quantity estimation of the mole rats role in formation of the habitat nanorelief-level diversity has been obtained by means of indexes of the landscape complexity and diversity.

Rebalance to Asia and the Pacific: Leveraging Vietnam to Counter-Balance China

Science.gov (United States)

2016-06-10

Invite Vietnam to participate in military exercises in the Pacific region ...................... 53 Increase military aid to Vietnam by... Malaysia is lying low, Brunei has solved its problem with China, Indonesia has no well-defined foreign policy on the subject, the Philippines has few...

O2 binding and CO2 sensitivity in haemoglobins of subterranean African mole rats

DEFF Research Database (Denmark)

Weber, Roy E.; Jarvis, Jennifer U. M.; Fago, Angela

2017-01-01

that predictably safeguard pulmonary loading under hypoxic and hypercapnic burrow conditions. The O2 binding characteristics are discussed in relation to available information on the primary structure of Hbs from adult and developmental stages of mammals subjected to hypoxia and hypercapnia and the molecular......Inhabiting deep and sealed subterranean burrows, mole rats exhibit a remarkable suite of specializations, including eusociality (living in colonies with single breeding queens), extraordinary longevity, cancer immunity and poikilothermy, and extreme tolerance of hypoxia and hypercapnia. With little...... and 2,3-diphosphoglycerate (DPG, the major allosteric modulator of Hb-O2 affinity in red blood cells) in four social and two solitary species of African mole rats (family Bathyergidae) originating from different biomes and soil types across Central and Southern Africa. We found no consistent patterns...

77 FR 60675 - Certain Frozen Fish Fillets From the Socialist Republic of Vietnam: Initiation of Antidumping...

Science.gov (United States)

2012-10-04

... DEPARTMENT OF COMMERCE International Trade Administration [A-552-801] Certain Frozen Fish Fillets... fillets (``fish'') from the Socialist Republic of Vietnam (``Vietnam''). The Department has determined... Notice of Antidumping Duty Order: Certain Frozen Fish Fillets From the Socialist Republic of Vietnam, 68...

77 FR 20356 - Certain Frozen Fish Fillets From the Socialist Republic of Vietnam: Extension of Preliminary...

Science.gov (United States)

2012-04-04

... DEPARTMENT OF COMMERCE International Trade Administration [A-552-801] Certain Frozen Fish Fillets... frozen fish fillets (``fish fillets'') from the Socialist Republic of Vietnam (``Vietnam''). These... on fish fillets from Vietnam.\\1\\ On October 3, 2011 the Department published a notice of initiation...

78 FR 40100 - Certain Frozen Fish Fillets from the Socialist Republic of Vietnam: Rescission of Antidumping...

Science.gov (United States)

2013-07-03

... DEPARTMENT OF COMMERCE International Trade Administration [A-552-801] Certain Frozen Fish Fillets... frozen fish fillets from the Socialist Republic of Vietnam (``Vietnam'') covering the period August 1... Certain Frozen Fish Fillets from the Socialist Republic of Vietnam: Initiation of Antidumping Duty New...

IS VIETNAM THE NEW ASIAN TIGER? SCOREBOARD ANDMACROECONOMIC EVALUATION OF THE ATTRACTIVENESS FORFOREIGN DIRECT INVESTMENT

Directory of Open Access Journals (Sweden)

Nathalie Homlong

2012-07-01

Full Text Available Followingeconomies like China and India,alsoVietnamhas managed toincreaseits attractiveness for foreign direct investmentsin recent years. In contrast tomany European economies Vietnam had overcome the financial and economiccrisisin 2008 quicklyand turned back to high growth rates already in 2010/11.Nevertheless many European economies and companies still regard Vietnam as anunstable and fragile economy. Therefore the questions arisewhich generalinvestment conditions are of importance for companies that are investing abroad,and which factors make Vietnam attractive asa business locationfor foreigncompanies? After a presentation of stylized facts about Vietnam and a discussionof location theories and location factors, we develop a scoring method to evaluategeneral investment conditions. Eight of the member states of the European Unionin Central and Eastern Europeare used as reference groups to test the scoreboardrating tool, before it is applied for Vietnam.

Cessation of reproduction-related spine elongation after multiple breeding cycles in female naked mole-rats.

Science.gov (United States)

Dengler-Crish, Christine M; Catania, Kenneth C

2009-01-01

The breeding female or "queen" naked mole-rat has a uniquely elongated body morphology attributed to the lengthening of the lumbar vertebral column that occurs during pregnancy. It is unknown whether this vertebral growth is a continuous process, or associated only with early reproductive experience. We compared pregnancy-related bone elongation in nascent primiparous queens and established queens to determine if this vertebral expansion was a lifelong process in these females. We also investigated the impact of lactation on vertebral elongation in these mole-rats because it is known to be a time of significant bone loss in other mammals. Our data show that after eight or more pregnancies, established queens no longer experienced a net gain in lumbar spine length over the reproductive cycle, whereas the nascent breeders demonstrated significant spine lengthening over this time. Despite the lack of net spine lengthening in established breeders, our results indicated that these queens still experienced some pregnancy-specific vertebral elongation. In naked mole-rats, pregnancy-induced bone elongation may serve the dual purposes of first lengthening the spine, and then once optimal spine size is achieved, serving as a homeostatic mechanism that prepares the spine for the mineral demands of lactation. Anat Rec, 2009. (c) 2008 Wiley-Liss, Inc.

A Mole in the Sole: Case Report on Eccrine Poroma | Das | Internet ...

African Journals Online (AJOL)

Eccrine poroma is a benign tumor which arises from the intraepidermal portion of the eccrine sweat glands. 81 year old diabetic grandma worried about her persistently uncontrolled blood sugar owing to a painless mole in the sole of right foot for 2 years. Excisional biopsy revealed a sweat duct benign eccrine poroma.

Vietnam | IDRC - International Development Research Centre

International Development Research Centre (IDRC) Digital Library (Canada)

... of its success, local fishery associations secured fishing management rights in 2009, a first in Vietnam. ... We continue to support online education through regional research to improve the quality of distance education. Total IDRC Support ...

Treatment Failure for Malaria in Vietnam

Centers for Disease Control (CDC) Podcasts

2017-06-05

WHO malaria expert, Dr. Charlotte Rasmussen, discusses anti-malarial drug resistance in Vietnam.  Created: 6/5/2017 by National Center for Emerging and Zoonotic Infectious Diseases (NCEZID).   Date Released: 6/5/2017.

The Influence of Chinese Master Taixu on Buddhism in Vietnam

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Elise A. DeVido

2015-02-01

Full Text Available From the 1920s, Vietnamese Buddhist reformers revitalized their religion, inspired in great part by the Chinese monk Taixu’s blueprint to modernize and systematize sangha education and temple administration, and by his idea ofrenjian fojiao, “Buddhism for this world,” emphasizing the centrality of education, modern publishing, social work, and Buddhist lay groups to Buddhism’s future in the modern world. This article first discusses the Chinese Buddhist revival, then the activities of Buddhist reformers in Vietnam 1920s–60s, and the flows of Buddhist personnel and materials between Vietnam and China. This article explores how renjian fojiao was interpreted and realized in Vietnam, especially its influence upon Thich Nhat Hanh as he developed his ideas on “Engaged Buddhism.”

Systematic review on irrational use of medicines in China and Vietnam.

Science.gov (United States)

Mao, Wenhui; Vu, Huyen; Xie, Zening; Chen, Wen; Tang, Shenglan

2015-01-01

Irrational use of medicines has been an issue concerned all over the world and the outlooks in developing countries are more severe. This study aimed to assess the different patterns of irrational use of medicines and its influential factors in China and Vietnam. A systematic review was performed on both published and grey literatures in English, Chinese and Vietnamese languages between 1993 and 2013 based on the WHO framework. Quality assessment was conducted on the basis of the Critical Appraisal Skills Programme. Key indicators were analyzed to compare the irrational use of medicines in two countries. A total of 67 published works about China and 29 about Vietnam were included, the majority of which were cross-sectional prescription studies in both China and Vietnam. Irrational use of medicines was found in both the countries but issues with polypharmacy as well as overuse of antibiotics were more severe in Vietnam while overuse of injections was unique to China. Various patterns of irrational use were also indicated between urban and rural areas, and among different levels of hospitals. Rarely does literature focus on the analysis of influential factors of irrational use of medicines. While lack of proper knowledge from both providers and patients were the most recognized influential factors in both countries, economic incentives from pharmaceutical companies in China, and weak control and regulation over prescriptions in Vietnam were the main factors attributed to this issue. Severe irrational use of medicines has been abundantly evidenced in both China and Vietnam, highlighting the importance of policy interventions on the issue. However, limited evidence on the appropriateness or its compliance (conformity) to guidelines of prescription has been found. In addition, convincing evidence on the underlying explanation of this issue is lacking, although economic incentives, health insurance coverage, and knowledge of service providers and users have been implied

Action of Bacopa monnieri to antagonize cisplatin-induced emesis in Suncus murinus (house musk shrew

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Ihsan Ullah

2017-04-01

Full Text Available Bacopa monnieri (BM, family Scrophulariaceae is used in several traditional systems of medicine for the management of epilepsy, depression, neuropathic pain, sleep disorders and memory deficits. The present study investigated the potential of BM methanol (BM-MetFr and BM n-butanol fractions (BM-ButFr to reduce chemotherapy-induced emesis in Suncus murinus (house musk shrew. Cisplatin (30 mg/kg, i.p. reliably induced retching and/or vomiting over a 2 day period. BM-MetFr (10–40 mg/kg, s.c. and BM-ButFr (5–20 mg/kg, s.c. antagonized the retching and/or vomiting response by ∼59.4% (p  0.05. In conclusion, the n-butanol fractions of BM have anti-emetic activity comparable with palonosetron and MPG. BM may be useful alone or in combination with other anti-emetic drugs for the treatment of chemotherapy-induced emesis in man.

Social and ecological challenges of market-oriented shrimp farming in Vietnam.

Science.gov (United States)

Lan, Ngo Thi Phuong

2013-01-01

Vietnam is one of the largest shrimp exporters in the world. Since 2010, Vietnam has earned about two billion dollars annually through shrimp exports. As a fertile area of greatest potential for agricultural production in Vietnam, the Mekong Delta has been a major contributor to the country's achievements, especially in the agricultural sector. During recent decades, trade liberation along with various policies in support of aquaculture has accelerated the development of shrimp production in the Delta. Based on an ethnographic study of shrimp farming in the Mekong Delta of Vietnam, I assert that along with great rewards arising from the expansion of shrimp farming areas, productivity, and export value, the shrimp industry has brought various environmental, economic and social challenges. Consequently, shrimp farming is a risky business and local inhabitants have relied on various strategies to cope with these challenges. Risk mitigation in shrimp production and labor migration are the two important strategies of local inhabitants for securing their livelihoods. Water pollution and poor quality post-larvae shrimp are direct consequences of market-oriented production.

78 FR 59915 - Certain Frozen Fish Fillets From the Socialist Republic of Vietnam: Initiation of Antidumping...

Science.gov (United States)

2013-09-30

... DEPARTMENT OF COMMERCE International Trade Administration [A-552-801] Certain Frozen Fish Fillets... fillets (``fish fillets'') from the Socialist Republic of Vietnam (``Vietnam'') that meets the statutory... INFORMATION: Background The AD order on fish fillets from Vietnam was published on August 12, 2003.\\1\\ On...

Social phobia and PTSD in Vietnam veterans.

Science.gov (United States)

Orsillo, S M; Heimberg, R G; Juster, H R; Garrett, J

1996-04-01

Posttraumatic stress disorder (PTSD) is the most prevalent psychological disorder experienced by Vietnam veterans. However, there are many other disorders and problems of adjustment, like social anxiety and social phobia, that have not been fully investigated in this population. This study examined the prevalence of social phobia and the comorbidity of social phobia and PTSD, and tested out a theory of the etiology of social anxiety in trauma victims. Forty one Vietnam combat veterans were interviewed and completed self-report measures assessing PTSD and social phobia. Adversity of homecoming was also assessed. Using a conservative multi-method assessment approach, 32% of the sample were found to be positive for both social phobia and PTSD. Veterans with PTSD were significantly more likely to carry an additional diagnosis of social phobia as compared to veterans without PTSD. Adversity of homecoming and shame about one's experience in Vietnam were significant predictors of current level of social anxiety over and above the effects of pre-military anxiety and severity of combat exposure. These observations suggest that social anxiety and social phobia may be significant problems among individuals with PTSD. Further, these findings offer preliminary support for the theory that posttrauma environment may impact upon the later development of social anxiety.

Altered composition of liver proteasome assemblies contributes to enhanced proteasome activity in the exceptionally long-lived naked mole-rat.

Science.gov (United States)

Rodriguez, Karl A; Edrey, Yael H; Osmulski, Pawel; Gaczynska, Maria; Buffenstein, Rochelle

2012-01-01

The longest-lived rodent, the naked mole-rat (Bathyergidae; Heterocephalus glaber), maintains robust health for at least 75% of its 32 year lifespan, suggesting that the decline in genomic integrity or protein homeostasis routinely observed during aging, is either attenuated or delayed in this extraordinarily long-lived species. The ubiquitin proteasome system (UPS) plays an integral role in protein homeostasis by degrading oxidatively-damaged and misfolded proteins. In this study, we examined proteasome activity in naked mole-rats and mice in whole liver lysates as well as three subcellular fractions to probe the mechanisms behind the apparently enhanced effectiveness of UPS. We found that when compared with mouse samples, naked mole-rats had significantly higher chymotrypsin-like (ChT-L) activity and a two-fold increase in trypsin-like (T-L) in both whole lysates as well as cytosolic fractions. Native gel electrophoresis of the whole tissue lysates showed that the 20S proteasome was more active in the longer-lived species and that 26S proteasome was both more active and more populous. Western blot analyses revealed that both 19S subunits and immunoproteasome catalytic subunits are present in greater amounts in the naked mole-rat suggesting that the observed higher specific activity may be due to the greater proportion of immunoproteasomes in livers of healthy young adults. It thus appears that proteasomes in this species are primed for the efficient removal of stress-damaged proteins. Further characterization of the naked mole-rat proteasome and its regulation could lead to important insights on how the cells in these animals handle increased stress and protein damage to maintain a longer health in their tissues and ultimately a longer life.

Challenges for municipal solid waste management practices in Vietnam

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Nguyen Duc Luong

2013-11-01

Full Text Available Municipal solid waste (MSW management is currently one of the major environmental problems facing by Vietnam. Improper management of MSW has caused adverse impacts on the environment, community health, and social-economic development. This study attempts to provide a review of the generation and characterization, disposal and treatment technologies of MSW to evaluate the current status and identify the problems of MSW management practices in Vietnam. Finally, this study is concluded with fruitful recommendations which may be useful in encouraging the responsible agencies to work towards the further improvement of the existing MSW management system.Doi: http://dx.doi.org/10.12777/wastech.1.1.17-21Citation:  Luong, N.D., Giang, H.M., Thanh, B.X. and Hung, N.T.  2013. Challenges for municipal solid waste management practices in Vietnam. Waste Technology 1(1:6-9.Doi: http://dx.doi.org/10.12777/wastech.1.1.17-21

Son preference in a rural village in North Vietnam.

Science.gov (United States)

Bélanger, Danièle

2002-12-01

This article explores the continuing preference for sons in the context of low fertility in Vietnam. Although the total fertility rate for Vietnam declined from 6.0 children per woman of reproductive age in 1979 to 2.2 children in 1998, demographic evidence shows that son preference remains strong and influences contraceptive and fertility behavior. This study examines the underlying factors for son preference in a rural village in North Vietnam. The methodology includes focus-group discussions, an in-depth study of 25 families, and ethnographic observation. Results indicate that sons are highly desired for their social, symbolic, and economic value. In spite of four decades of socialist policies aimed at reducing gender-based inequalities and at weakening the patriarchal kinship system, the desire for sons continues to drive the family-building process. The article also indicates a gap between discourse and social practice with respect to roles assigned to children on the basis of their sex.

MOLED: Simulation of multilayer organic light emitting diodes

Science.gov (United States)

Houili, H.; Tutiš, E.; Lütjens, H.; Bussac, M. N.; Zuppiroli, L.

2003-12-01

MOLED solves the dynamics of electrons and holes in multilayer Organic Light Emitting Diodes (OLED). The carriers are injected on the positive and negative electrodes of the device by tunneling through a potential barrier. Thermal excitation processes across the barrier are also included. In the interior of the device the electron-hole recombination occurs when the two carriers are close enough, according to a model inspired from the one of Langevin. A fraction of these recombined pairs gives photons. The charge transport inside the organic material occurs through hopping. Several choices of mobility formulae are available in the code. MOLED can be used for OLEDs with an arbitrary number of layers. The output consists of numerous fields that describe the device performance. For example, there are the current, the recombination and the charge density distributions, the electric field distribution, the current-voltage characteristics and the device internal quantum efficiency. Program summaryTitle of program: MOLED Catalogue identifier: ADSG Program summary URL:http://cpc.cs.qub.ac.uk/summaries/ADSG Program obtainable from: CPC Program Library, Queen's University of Belfast, N. Ireland Operating systems under which the program has been tested: Unix, Linux Programming language used: FORTRAN 90 Memory required to execute with typical data: 2 MB No. of bytes in distributed program: 26 942 No. of bits in a word: 64 Peripherals used: permanent disk storage No. of lines in distributed program, including test data, etc.: 3695 Distribution format: tar gzip file Nature of the physical problem: Injection of electrons and holes into an organic electroluminescent material occurs through tunneling from metal electrodes. The transport of carriers inside the molecular medium proceeds by hopping from one molecule to another. The emission of light is a result of their radiative Langevin recombination (for a review see [Scott et al., Synthetic Metals 111-112 (2000) 289; Friend et al

A new definition for the mole based on the Avogadro constant: a journey from physics to chemistry.

Science.gov (United States)

Milton, Martin J T

2011-10-28

The mole is the most recent addition to the set of base units that form the International System of Units, although its pre-cursor the 'gram-molecule', had been in use by both physicists and chemists for more than 120 years. A proposal has been published recently to establish a new definition for the mole based on a fixed value for the Avogadro constant. This would introduce consistent relative uncertainties for the molar and the atomic masses while making no change to the system of relative atomic masses ('atomic weights'). Although the proposal would have little impact on the measurement uncertainty of practical work, it has stimulated considerable debate about the mole and the nature of the quantity amount of substance. In this paper, the rationale for the new definition is explained against the background of changes in the way the quantity amount of substance has been used, from its first use during the early development of thermodynamics through to the use of the 'number of gram-molecules' at the end of the nineteenth century.

Morphodynamics of seasonally closed coastal inlets at the central coast of Vietnam

NARCIS (Netherlands)

Tran, T.T.

2011-01-01

Situated in a monsoon-prone humid tropical region, Vietnam is affected by both oceanic and continental climates causing disasters to the country like riverine flooding and storm induced damage. The coastal districts of Vietnam have a population of about 18 million habitants, account for nearly one

Clinical significance of measurement of changes of serum TNF-α and EGF levels after chemotherapy in patients with malignant hydatidiform mole

International Nuclear Information System (INIS)

Chen Xiaochao; Zhou Dongxia; Zhang Liming

2008-01-01

Objective: To study the clinical significance of changes of serum TNF-α and EGF levels after chemotherapy in patients with malignant hydatidiform mole. Methods: Serum TNF-α, EGF levels (with RIA) were measured both before and after chemotherapy in 32 patients with malignant hydatidiform mole as well as in 35 controls. Results: Before chemotherapy, serum TNF- α and EGF levels were significantly higher in the patients than those in controls (P<0.01). Six months after chemotherapy, serum TNF-α and EGF levels, though dropped markedly, remained significantly higher than those in controls (P<0.05). Conclusion: Development of malignant hydatidiform mole in patients was closely related to the serum TNF-α and EGF levels. (authors)

Comparative analysis of genome maintenance genes in naked mole rat, mouse, and human

NARCIS (Netherlands)

S.L. Macrae (Sheila L.); Q. Zhang (Quanwei); C. Lemetre (Christophe); I. Seim (Inge); R.B. Calder (Robert B.); J.H.J. Hoeijmakers (Jan); Y. Suh (Yousin); V.N. Gladyshev (Vadim N.); A. Seluanov (Andrei); V. Gorbunova (Vera); J. Vijg (Jan); Z.D. Zhang (Zhengdong D.)

2015-01-01

textabstractGenome maintenance (GM) is an essential defense system against aging and cancer, as both are characterized by increased genome instability. Here, we compared the copy number variation and mutation rate of 518 GM-associated genes in the naked mole rat (NMR), mouse, and human genomes. GM

Agent Orange exposure and attributed health effects in Vietnam veterans.

Science.gov (United States)

Young, Alvin L; Cecil, Paul F

2011-07-01

Serum dioxin studies of Vietnam (VN) veterans, military historical records of tactical herbicide use in Vietnam, and the compelling evidence of the photodegradation of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and other aspects of environmental fate and low bioavailability of TCDD are consistent with few, if any, ground troop veterans being exposed to Agent Orange. That conclusion, however, is contrary to the presumption by the Department of Veterans Affairs (DVA) that military service in Vietnam anytime from January 9, 1962 to May 7, 1975 is a proxy for exposure to Agent Orange. The DVA assumption is inconsistent with the scientific principles governing determinations of disease causation. The DVA has nonetheless awarded Agent Orange-related benefits and compensation to an increasing number of VN veterans based on the presumption of exposure and the published findings of the Institute of Medicine that there is sufficient evidence of a "statistical association" (a less stringent standard than "causal relationship") between exposure to tactical herbicides or TCDD and 15 different human diseases. A fairer and more valid approach for VN veterans would have been to enact a program of "Vietnam experience" benefits for those seriously ill, rather than benefits based on the dubious premise of injuries caused by Agent Orange.

The Empirical Analysis of Cigarette Tax Avoidance and Illicit Trade in Vietnam, 1998-2010

OpenAIRE

Nguyen, Minh Thac; Denniston, Ryan; Nguyen, Hien Thi Thu; Hoang, Tuan Anh; Ross, Hana; So, Anthony D.

2014-01-01

Illicit trade carries the potential to magnify existing tobacco-related health care costs through increased availability of untaxed and inexpensive cigarettes. What is known with respect to the magnitude of illicit trade for Vietnam is produced primarily by the industry, and methodologies are typically opaque. Independent assessment of the illicit cigarette trade in Vietnam is vital to tobacco control policy. This paper measures the magnitude of illicit cigarette trade for Vietnam between 199...

Intelligence Operations In Small Wars: A Comparison Of The Malayan Emergency And Vietnam War

Science.gov (United States)

2013-04-01

Effect, 18. 41 Spencer C. Tucker, David Coffey, Nguyen Cong Luan, Nike Nichols, and Sandra Wittman, eds, Encyclopedia of the Vietnam War Volume One: A...War: The Unexamined Victories and Final Tragedy of America’s Last Years in Vietnam, (Orlando, FL :Harcourt, Inc ., 1999), 72-73. 91 Sorley, A Better...Victories and Final Tragedy of America’s Last Years in Vietnam. Orlando, FL: Harcourt, Inc ., 1999. Stubbs, Richard. Hearts and Minds in

Effect of the Ti/B4C mole ratio on the reaction products and reaction mechanism in an Al–Ti–B4C powder mixture

International Nuclear Information System (INIS)

Zhang, Jingjing; Lee, Jung-Moo; Cho, Young-Hee; Kim, Su-Hyeon; Yu, Huashun

2014-01-01

The effect of the Ti/B 4 C mole ratio on the fabrication behavior of Al composites is investigated using Al–Ti–B 4 C powder mixtures as reactants. The quick spontaneous infiltration (QSI) process combined with the combustion reaction and DTA analysis were used. According to the thermodynamic predictions, which are verified in the experimental results, TiB 2 is formed in all the samples whereas TiC is only formed in reactants with a Ti/B 4 C mole ratio of more than two. The C atoms from the reacted B 4 C do not move into TiC but instead they move into Al 3 BC or Al 4 C 3 when the Ti/B 4 C mole ratio is less than two. In addition, the reaction mechanism with a Ti/B 4 C mole ratio of 0.75 is investigated extensively. - Highlights: • The critical role of the Ti/B 4 C mole ratio on the reaction products of Al–Ti–B 4 C was studied using experiments. • The experimental results are also supported by thermodynamic calculations presented in this paper. • The reaction mechanism with a Ti/B 4 C mole ratio of 0.75 is investigated extensively

Cutaneous and periodontal inputs to the cerebellum of the naked mole-rat (Heterocephalus glaber).

Science.gov (United States)

Sarko, Diana K; Leitch, Duncan B; Catania, Kenneth C

2013-01-01

The naked mole-rat (Heterocephalus glaber) is a small fossorial rodent with specialized dentition that is reflected by the large cortical area dedicated to representation of the prominent incisors. Due to naked mole-rats' behavioral reliance on the incisors for digging and for manipulating objects, as well as their ability to move the lower incisors independently, we hypothesized that expanded somatosensory representations of the incisors would be present within the cerebellum in order to accommodate a greater degree of proprioceptive, cutaneous, and periodontal input. Multiunit electrophysiological recordings targeting the ansiform lobule were used to investigate tactile inputs from receptive fields on the entire body with a focus on the incisors. Similar to other rodents, a fractured somatotopy appeared to be present with discrete representations of the same receptive fields repeated within each folium of the cerebellum. These findings confirm the presence of somatosensory inputs to a large area of the naked mole-rat cerebellum with particularly extensive representations of the lower incisors and mystacial vibrissae. We speculate that these extensive inputs facilitate processing of tactile cues as part of a sensorimotor integration network that optimizes how sensory stimuli are acquired through active exploration and in turn adjusts motor outputs (such as independent movement of the lower incisors). These results highlight the diverse sensory specializations and corresponding brain organizational schemes that have evolved in different mammals to facilitate exploration of and interaction with their environment.

Cutaneous and periodontal inputs to the cerebellum of the naked mole-rat (Heterocephalus glaber

Directory of Open Access Journals (Sweden)

Diana K Sarko

2013-11-01

Full Text Available The naked mole-rat (Heterocephalus glaber is a small fossorial rodent with specialized dentition that is reflected by the large cortical area dedicated to representation of the prominent incisors. Due to naked mole-rats’ behavioral reliance on the incisors for digging and for manipulating objects, as well as their ability to move the lower incisors independently, we hypothesized that expanded somatosensory representations of the incisors would be present within the cerebellum in order to accommodate a greater degree of proprioceptive, cutaneous, and periodontal input. Multiunit electrophysiological recordings targeting the ansiform lobule were used to investigate tactile inputs from receptive fields on the entire body with a focus on the incisors. Similar to other rodents, a fractured somatotopy appeared to be present with discrete representations of the same receptive fields repeated within each folium of the cerebellum. These findings confirm the presence of somatosensory inputs to a large area of the naked mole-rat cerebellum with particularly extensive representations of the lower incisors and mystacial vibrissae. We speculate that these extensive inputs facilitate processing of tactile cues as part of a sensorimotor integration network that optimizes how sensory stimuli are acquired through active exploration and in turn adjusts motor outputs (such as independent movement of the lower incisors. These results highlight the diverse sensory specializations and corresponding brain organizational schemes that have evolved in different mammals to facilitate exploration of and interaction with their environment.

Challenging the inbreeding hypothesis in a eusocial mammal: population genetics of the naked mole-rat, Heterocephalus glaber.

Science.gov (United States)

Ingram, Colleen M; Troendle, Nicholas J; Gill, Clare A; Braude, Stanton; Honeycutt, Rodney L

2015-10-01

The role of genetic relatedness in the evolution of eusociality has been the topic of much debate, especially when contrasting eusocial insects with vertebrates displaying reproductive altruism. The naked mole-rat, Heterocephalus glaber, was the first described eusocial mammal. Although this discovery was based on an ecological constraints model of eusocial evolution, early genetic studies reported high levels of relatedness in naked mole-rats, providing a compelling argument that low dispersal rates and consanguineous mating (inbreeding as a mating system) are the driving forces for the evolution of this eusocial species. One caveat to accepting this long-held view is that the original genetic studies were based on limited sampling from the species' geographic distribution. A growing body of evidence supports a contrary view, with the original samples not representative of the species-rather reflecting a single founder event, establishing a small population south of the Athi River. Our study is the first to address these competing hypotheses by examining patterns of molecular variation in colonies sampled from north and south of the Athi and Tana rivers, which based on our results, serve to isolate genetically distinct populations of naked mole-rats. Although colonies south of the Athi River share a single mtDNA haplotype and are fixed at most microsatellite loci, populations north of the Athi River are considerably more variable. Our findings support the position that the low variation observed in naked mole-rat populations south of the Athi River reflects a founder event, rather than a consequence of this species' unusual mating system. © 2015 John Wiley & Sons Ltd.

PTSD and Use of Outpatient General Medical Services Among Veterans of the Vietnam War.

Science.gov (United States)

Schlenger, William E; Mulvaney-Day, Norah; Williams, Christianna S; Kulka, Richard A; Corry, Nida H; Mauch, Danna; Nagler, Caryn F; Ho, Chia-Lin; Marmar, Charles R

2016-05-01

The primary goal of this analysis was to assess whether recent use of outpatient services for general medical concerns by Vietnam veterans varies according to level of posttraumatic stress disorder (PTSD) symptomatology over time. Another goal was to determine whether PTSD symptomatology was associated with veterans' reports of discussing behavioral health issues as part of a general medical visit. Self-reported service use data and measures of PTSD were from a nationally representative sample of 848 male and female Vietnam theater veterans (individuals who were deployed to the Vietnam theater of operations) who participated in the National Vietnam Veterans Longitudinal Study, a 25-year follow-up of a cohort of veterans originally interviewed from 1984-1988 as part of the National Vietnam Veterans Readjustment Study. Four categories of PTSD symptomatology course over 25 years were defined, and logistic regression models were used to assess their relationship with recent use of outpatient general medical services. Male and female theater veterans with high or increasing PTSD symptomatology over the period were more likely than those with low symptomatology to report recent VA outpatient visits. Males in the increasing and high categories were also more likely to discuss behavioral health issues at general medical visits. Vietnam veterans with high and increasing PTSD symptomatology over time were likely to use VA outpatient general health services. Attention to stressors of the aging process and to persistence of PTSD symptoms is important for Vietnam veterans, as is addressing PTSD with other psychiatric and medical comorbidities within the context of outpatient general medical care.

Building on and spinning off: Sandia National Labs` creation of sensors for Vietnam

Energy Technology Data Exchange (ETDEWEB)

Ullrich, R.

1996-12-31

This paper discusses Sandia National Laboratories` development of new technologies for use in the Vietnam War - specifically the seismic sensors deployed to detect troop and vehicle movement - first along the Ho Chi Minh Trail and later in perimeter defense for American military encampments in South Vietnam. Although the sensor story is a small one, it is interesting because it dovetails nicely with our understanding of the war in Vietnam and its frustrations; of the creation of new technologies for war and American enthusiasm for that technology; and of a technological military and the organizational research and a m am development structure created to support it. Within the defense establishment, the sensors were proposed within the context of a larger concept - that of a barrier to prevent the infiltration of troops and supplies from North Vietnam to the South. All of the discussion of the best way to fight in Vietnam is couched in the perception that this was a different kind of war than America was used to fighting. The emphasis was on countering the problems posed by guerrilla/revolutionary warfare and eventually by the apparent constraints of being involved in a military action, not an outright war. The American response was to find the right technology to do the job - to control the war by applying a technological tincture to its wounds and to make the war familiar and fightable on American terms. And, when doubts were raised about the effectiveness of applying existing technologies (namely, the bombing of North Vietnam and Laos), the doubters turned to new technologies. The sensors that were developed for use in Vietnam were a direct product of this sort of thinking - on the part of the engineers at Sandia who created the sensors, the civilian scientific advisors who recommended them, and, ultimately, the soldiers in the field who had to use them.

Economic reform in Vietnam - the role of foreign direct investment and trade policy

International Nuclear Information System (INIS)

Tran, D.L.

1998-11-01

Vietnam was one of the five poorest countries in the world in the 1980's. Since then, Vietnam has adopted a market economic policy, and she has made substantial economic progress. In the last 10 years Meanwhile Vietnam's per capita income has increased by 3 times, the volume of export doubled very two years, and the inflation rate was reduced to 4.5 % in 1997 from 775 % in 1986. The GDP also has increased, the exchange rate with the US$ was stabilized and foreign direct investment (FDI) and trade has increased. There was about US$35 billion were invested by the foreign investors between 1987 to the middle of June 1998. However, the current crisis in the economies of Southeast Asian countries has put pressure on Vietnam to rethink seriously her future reform program with respect to stabilization and sustainable current economic policies. Since FDI is an imperative for the development of a country like Vietnam, it is necessary to use this capital very careful for her economy. Thus, the main objective of this dissertation is to study the role of FDI in the development of Vietnam. To examine this objective, various investigations were made, especially focusing on development dimensions such as reforming state enterprises, foreign trade policy, foreign investment and so on. Therefore, in the future, FDI and privatization policies should be strengthened to maintain and create an international market. Moreover, there are some major reforms required to transform the state sector into a private sector with appropriate policy measures, such as improving management of financial companies, developing the agricultural sector and minimizing bureaucracy and red tapism of the government. This dissertation provides a set of recommendations how to strengthen Vietnams economic and market situation in the 21st century. (author)

Nonfatal Injuries and Psychosocial Correlates among Middle School Students in Cambodia and Vietnam

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Karl Peltzer

2017-03-01

Full Text Available The aim of the study was to estimate the prevalence and psychosocial correlates of nonfatal injury among middle school students in Cambodia and Vietnam. Cross-sectional data from 7137 school children (mean age 15.5 years, SD = 1.4 who were randomly sampled for participation in nationally representative Global School-based Health Surveys (GSHS in Cambodia and Vietnam were analyzed. The proportion of school children reporting one or more serious injuries in the past year was 22.6% among boys and 17.5% among girls in Cambodia and 34.3% among boys and 25.1% among girls in Vietnam. The most prevalent cause of the most serious injury in Cambodia was traffic injuries (4.7% among boys and 4.3% among girls and in Vietnam it was falls (10.0% among boys and 7.0% among girls. In multinomial logistic regression analyses, experiencing hunger (as an indicator for low socioeconomic status and drug use were associated with having sustained one injury and two or more injuries in the past 12 months in Cambodia. In addition, poor mental health was associated with two or more injuries. In Vietnam, being male, experiencing hunger, current alcohol use, poor mental health and ever having had sex were associated with having sustained one injury and two or more injuries in the past 12 months. Several psychosocial variables were identified which could help in designing injury prevention strategies among middle school children in Cambodia and Vietnam.

Volatile constituents of the essential oils of two Polygonum species from Vietnam

NARCIS (Netherlands)

Dung, N.X.; Van, le H.; Moi, La Dinh; Cu, Lu'u Dam; Leclercq, P.A.

1994-01-01

Polygonum species grown in many places in Vietnam, esp. on the rice-field. It is used in the traditional medicine. After Pham Hoang Ho until now in Vietnam, 40 Polygonum species have been found. From the polygonum genus (Family Polygonaceae) the essential oils of 2 species are reported: Polygonum

Decentralized forest governance in central Vietnam

NARCIS (Netherlands)

Tran Nam, T.; Burgers, P.P.M.

2012-01-01

A major challenge in decentralized forest governance in Vietnam is developing a mechanism that would support both reforestation and poverty reduction among people in rural communities. To help address this challenge, Forest Land Allocation (FLA) policies recognize local communities and individuals

The naked mole-rat exhibits an unusual cardiac myofilament protein profile providing new insights into heart function of this naturally subterranean rodent.

Science.gov (United States)

Grimes, Kelly M; Barefield, David Y; Kumar, Mohit; McNamara, James W; Weintraub, Susan T; de Tombe, Pieter P; Sadayappan, Sakthivel; Buffenstein, Rochelle

2017-12-01

The long-lived, hypoxic-tolerant naked mole-rat well-maintains cardiac function over its three-decade-long lifespan and exhibits many cardiac features atypical of similar-sized laboratory rodents. For example, they exhibit low heart rates and resting cardiac contractility, yet have a large cardiac reserve. These traits are considered ecophysiological adaptations to their dank subterranean atmosphere of low oxygen and high carbon dioxide levels and may also contribute to negligible declines in cardiac function during aging. We asked if naked mole-rats had a different myofilament protein signature to that of similar-sized mice that commonly show both high heart rates and high basal cardiac contractility. Adult mouse ventricles predominantly expressed α-myosin heavy chain (97.9 ± 0.4%). In contrast, and more in keeping with humans, β myosin heavy chain was the dominant isoform (79.0 ± 2.0%) in naked mole-rat ventricles. Naked mole-rat ventricles diverged from those of both humans and mice, as they expressed both cardiac and slow skeletal isoforms of troponin I. This myofilament protein profile is more commonly observed in mice in utero and during cardiomyopathies. There were no species differences in phosphorylation of cardiac myosin binding protein-C or troponin I. Phosphorylation of both ventricular myosin light chain 2 and cardiac troponin T in naked mole-rats was approximately half that observed in mice. Myofilament function was also compared between the two species using permeabilized cardiomyocytes. Together, these data suggest a cardiac myofilament protein signature that may contribute to the naked mole-rat's suite of adaptations to its natural subterranean habitat.

A Comparative Analysis of Social Work in Vietnam and Canada: Rebirth and Renewal

Directory of Open Access Journals (Sweden)

Douglas Durst

2015-03-01

Full Text Available Social work education is rapidly developing in the Socialist Republic of Vietnam and it is facing new challenges as it blends the historical, political and cultural influences. This article reviews and compares the historical and recent developments of social work in Canada and Vietnam. Canadian social work developed in Euro-western culture and its values, whereas, Vietnam suffered under French colonialism, a 30 year war of independence and then economic depression. For many years, social work remained nebulous but in recent years, the country has seen a rebirth of social work. Field education is the link from theory to practice and is often where differences between the two countries become evident. The article concludes with a discussion on the professionalization of social work and its future contribution to the emerging “new” Vietnam.

The Vietnam Experience in Perspective.

Science.gov (United States)

Nurse, Ronald J.; Fleming, Dan B.

1982-01-01

Ten recent editions of secondary school-level United States history textbooks were analyzed to determine coverage and balance of the Vietnam War. Treatment of topics such as Vietnamese culture, the roles of wartime leaders, the aims of the United States government, the antiwar movement, and costs of the war are discussed. (PP)

Greening textile industry in Vietnam

NARCIS (Netherlands)

Nguyen Thi Phuong, L.

2011-01-01

The textile and garment industry has made a remarkable contribution to the economic development of Vietnam and employs currently a large labor force of 2.5 million people.However, the textile industry is also seen as a most polluting and unsustainable industry due to the use of

Risk Factors for Non-communicable Diseases in Vietnam: A Focus on Pesticides

Directory of Open Access Journals (Sweden)

Hoang V. Dang

2017-09-01

Full Text Available Agent Orange, which was used in southern Vietnam, is confirmed the main source of dioxin exposure in Vietnam. Since early 1990s, agriculture of Vietnam has attained advances under intensive cultivation. Both production and yields per crop have increased significantly at the farm level, but the quantity of pesticides used in agriculture also increased in the absence of regulations and good practices. Illegal business of pesticides with false labels, as well as marketing of expired or poor quality products in stores without license are popular in Vietnam. Misuse and improper use in agriculture in Vietnam has led to a variety of problems, such as environmental pollution (including food producing animals and adverse health impact on animals and humans. Open dumpsites worsen the general scenario. Similar to the environmental exposure, human exposure to DDT in Vietnam was ranked among the highest worldwide, with recognized effects. Exposed communities have to face birth defects, health disorders and non-communicable diseases (NCDs, from metabolic syndrome, asthma, infertility and other reproductive disorders through to diabetes, obesity, cardiovascular and neurodegenerative diseases, and cancer. A common feature of many chronic disorders and NCDs is metabolic disruption: environmental chemical factors disturb cellular homeostasis, thus affecting the ability of the body to restore a functional internal environment. Among these, endocrine disrupting pesticides can interfere with the action of hormones including metabolic hormones, and are likely to represent the main concern for developmentally-induced NCDs. Since pesticides are often persistent and bio-accumulate in the food chain through the living environment of food-producing organisms, this paper discusses relevant aspects of risk assessment, risk communication and risk management.

Pre-evacuation hCG glycoforms in uneventful complete hydatidiform mole and persistent trophoblastic disease.

NARCIS (Netherlands)

Thomas, C.M.G.; Kerkmeijer, L.G.W.; Ariaens, H.J.; Steen, R. van der; Massuger, L.F.A.G.; Sweep, F.C.

2010-01-01

OBJECTIVE: To investigate whether the glycoform distribution patterns of human chorionic gonadotropin (hCG) obtained by chromatofocusing in pre-evacuation serum are different for patients who will eventually develop into persistent trophoblastic disease in case of complete hydatidiform mole

Van stichtelijke fraseologie naar redelijkheid. De PvdA en de oorlog in Vietnam, 1964-1973

Directory of Open Access Journals (Sweden)

F. Zuijdam

2002-01-01

Full Text Available The Dutch Labour Party and the war in VietnamDuring the 1960s, many people demonstrated against the war in Vietnam. However, the Dutch government, along with most of the major political parties in the Netherlands, chose to ignore the vox populi and refused to reject America's policy regarding Vietnam. One exception to that rule was the Dutch Labour Party. From an early stage, the social-democrats had kept a critical watch on American policy and exhibited an increasing resistance to the subsequent military intervention. In adopting this attitude towards the Vietnam War, the Labour Party had to take several developments into account. The reduction in Cold War tensions, the Cultural Revolution and, above all, the shifts in domestic politics all affected the point of view on Vietnam. One very important consideration that should be taken into account was that, at the time, the Labour Party was trapped between new forms of activism and firm opposition, on the one hand, and the wish to join the government on the other. Under these circumstances, a formal letter to the American Ambassador seemed to be the safest vehicle through which Labour's critical attitude towards Vietnam could be expressed.

Posttraumatic stress disorder among black Vietnam veterans.

Science.gov (United States)

Allen, I M

1986-01-01

Because of racism in the military and racial and social upheaval in the United States during the Vietnam War years, as well as limited opportunities for blacks in the postwar period, black veterans of the Vietnam War often harbor conflicting feelings about their wartime experiences and have difficulty rationalizing brutality against the Vietnamese. As a result, black veterans suffer from posttraumatic stress disorder (PTSD) at a higher rate than white veterans. Diagnosis and treatment of PTSD in black veterans is complicated by the tendency to misdiagnose black patients, by the varied manifestations of PTSD, and by patients' frequent alcohol and drug abuse and medical, legal, personality, and vocational problems. The author presents his and others' recommendations about ways to treat black veterans with PTSD.

Experimental nuclear physics in Vietnam - recent status

International Nuclear Information System (INIS)

Tran Thanh Minh

1995-01-01

It is really difficult to determine the exact date for the starting of nuclear physics research in Vietnam. Serious research on experimental nuclear physics began only since 1972 with the installation of such nuclear instrument like microtron accelerator, neutron generator, etc. During the past 20 years, hundred of research works have been published in local and foreign scientific journals. In the 5th national conference in Physics held in Hanoi in October 1993, at the Nuclear Physics section, 62 reports were presented reflecting the situation of nuclear physics research in the recent years, especially in the past five years. This review introduces its main results and formulates some perspectives of development in the late nineties in Vietnam. (K.A.). 27 refs., 4 figs., 6 tabs

Community structure variability of Uropodina mites (Acari: Mesostigmata) in nests of the common mole, Talpa europaea, in Central Europe

OpenAIRE

Napiera?a, Agnieszka; M?dra, Anna; Leszczy?ska-Deja, Kornelia; Gwiazdowicz, Dariusz J.; Go?dyn, Bart?omiej; B?oszyk, Jerzy

2016-01-01

Underground nests of Talpa europaea, known as the common mole, are very specific microhabitats, which are also quite often inhabited by various groups of arthropods. Mites from the suborder Uropodina (Acari: Mesostigmata) are only one of them. One could expect that mole nests that are closely located are inhabited by communities of arthropods with similar species composition and structure. However, results of empirical studies clearly show that even nests which are close to each other can be ...

Synaptonemal complex analysis of interracial hybrids between the Moscow and Neroosa chromosomal races of the common shrew Sorex araneus showing regular formation of a complex meiotic configuration (ring-of-four).

Science.gov (United States)

Matveevsky, Sergey N; Pavlova, Svetlana V; Maret M Acaeva; Oxana L Kolomiets

2012-01-01

Immunocytochemical and electron microscopic analysis of synaptonemal complexes (SCs) was carried out for the first time in homozygotes and complex Robertsonian heterozygotes (hybrids) of the common shrew, Sorex araneus Linnaeus, 1758, from a newly discovered hybrid zone between the Moscow and the Neroosa chromosomal races. These races differ in four monobrachial homologous metacentrics, and closed SC tetravalent is expected to be formed in meiosis of a hybrid. Indeed, such a multivalent was found at meiotic prophase I in hybrids. Interactions between multivalent and both autosomes and/or the sex chromosomes were observed. For the first time we have used immunocytochemical techniques to analyse asynapsis in Sorex araneus and show that the multivalent pairs in an orderly fashion with complete synapsis. Despite some signs of spermatocytes arrested in the meiotic prophase I, hybrids had large number of active sperm. Thus, Moscow - Neroosa hybrid males that form a ring-of-four meiotic configuration are most likely not sterile. Our results support previous demonstrations that monobrachial homology of metacentrics of the common shrew does not lead to complete reproductive isolation between parapatric chromosomal races of the species.

Synaptonemal complex analysis of interracial hybrids between the Moscow and Neroosa chromosomal races of the common shrew Sorex araneus showing regular formation of a complex meiotic configuration (ring-of-four

Directory of Open Access Journals (Sweden)

Sergey Matveevsky

2012-09-01

Full Text Available Immunocytochemical and electron microscopic analysis of synaptonemal complexes (SCs was carried out for the first time in homozygotes and complex Robertsonian heterozygotes (hybrids of the common shrew, Sorex araneus Linnaeus, 1758, from a newly discovered hybrid zone between the Moscow and the Neroosa chromosomal races. These races differ in four monobrachial homologous metacentrics, and closed SC tetravalent is expected to be formed in meiosis of a hybrid. Indeed, such a multivalent was found at meiotic prophase I in hybrids. Interactions between multivalent and both autosomes and/or the sex chromosomes were observed. For the first time we have used immunocytochemical techniques to analyse asynapsis in S. araneus and show that the multivalent pairs in an orderly fashion with complete synapsis. Despite some signs of spermatocytes arrested in the meiotic prophase I, hybrids had large number of active sperm. Thus, Moscow – Neroosa hybrid males that form a ring-of-four meiotic configuration are most likely not sterile. Our results support previous demonstrations that monobrachial homology of metacentrics of the common shrew does not lead to complete reproductive isolation between parapatric chromosomal races of the species.

Armor in Vietnam

Science.gov (United States)

1976-05-01

battles a-Riuot the insurgent enemy, especially with armor. French contingents were present in Tndo Chinh P-w early as 1852, but it was not until 1884...committed to Vietnam were straight infantry. These troons er•A tran -norted in hn4±{ copters and usually airlifted to the battle zone; however, once...0STAINf0 FROM VKTNAM NATIONAL MAP SERVICE (NOS) PHU-YEN OCTOBER 19665 OARLAC ......... KKAN1+ HOA QLWA- DUC TUYEN- DUC PHUOC- NINH_ C;ry OF -10 T CAM RANK TAY

Development of Two-Tier Diagnostic Test Pictorial-Based for Identifying High School Students Misconceptions on the Mole Concept

Science.gov (United States)

Siswaningsih, W.; Firman, H.; Zackiyah; Khoirunnisa, A.

2017-02-01

The aim of this study was to develop the two-tier pictorial-based diagnostic test for identifying student misconceptions on mole concept. The method of this study is used development and validation. The development of the test Obtained through four phases, development of any items, validation, determination key, and application test. Test was developed in the form of pictorial consisting of two tier, the first tier Consist of four possible answers and the second tier Consist of four possible reasons. Based on the results of content validity of 20 items using the CVR (Content Validity Ratio), a number of 18 items declared valid. Based on the results of the reliability test using SPSS, Obtained 17 items with Cronbach’s Alpha value of 0703, the which means that items have accepted. A total of 10 items was conducted to 35 students of senior high school students who have studied the mole concept on one of the high schools in Cimahi. Based on the results of the application test, student misconceptions were identified in each label concept in mole concept with the percentage of misconceptions on the label concept of mole (60.15%), Avogadro’s number (34.28%), relative atomic mass (62, 84%), relative molecule mass (77.08%), molar mass (68.53%), molar volume of gas (57.11%), molarity (71.32%), chemical equation (82.77%), limiting reactants (91.40%), and molecular formula (77.13%).

Altered composition of liver proteasome assemblies contributes to enhanced proteasome activity in the exceptionally long-lived naked mole-rat.

Directory of Open Access Journals (Sweden)

Karl A Rodriguez

Full Text Available The longest-lived rodent, the naked mole-rat (Bathyergidae; Heterocephalus glaber, maintains robust health for at least 75% of its 32 year lifespan, suggesting that the decline in genomic integrity or protein homeostasis routinely observed during aging, is either attenuated or delayed in this extraordinarily long-lived species. The ubiquitin proteasome system (UPS plays an integral role in protein homeostasis by degrading oxidatively-damaged and misfolded proteins. In this study, we examined proteasome activity in naked mole-rats and mice in whole liver lysates as well as three subcellular fractions to probe the mechanisms behind the apparently enhanced effectiveness of UPS. We found that when compared with mouse samples, naked mole-rats had significantly higher chymotrypsin-like (ChT-L activity and a two-fold increase in trypsin-like (T-L in both whole lysates as well as cytosolic fractions. Native gel electrophoresis of the whole tissue lysates showed that the 20S proteasome was more active in the longer-lived species and that 26S proteasome was both more active and more populous. Western blot analyses revealed that both 19S subunits and immunoproteasome catalytic subunits are present in greater amounts in the naked mole-rat suggesting that the observed higher specific activity may be due to the greater proportion of immunoproteasomes in livers of healthy young adults. It thus appears that proteasomes in this species are primed for the efficient removal of stress-damaged proteins. Further characterization of the naked mole-rat proteasome and its regulation could lead to important insights on how the cells in these animals handle increased stress and protein damage to maintain a longer health in their tissues and ultimately a longer life.

Formal and informal credit in four provinces of Vietnam

DEFF Research Database (Denmark)

Barslund, Mikkel; Tarp, Finn

2008-01-01

This paper uses a survey of 932 rural households to uncover how the rural credit market operates in Vietnam. Households obtain credit through formal and informal lenders. Formal loans are almost entirely for production and asset accumulation, while informal loans are used for consumption smoothen......This paper uses a survey of 932 rural households to uncover how the rural credit market operates in Vietnam. Households obtain credit through formal and informal lenders. Formal loans are almost entirely for production and asset accumulation, while informal loans are used for consumption...

Cancer resistance in the blind mole rat is mediated by concerted necrotic cell death mechanism

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Gorbunova, Vera; Hine, Christopher; Tian, Xiao; Ablaeva, Julia; Gudkov, Andrei V.; Nevo, Eviatar; Seluanov, Andrei

2012-01-01

Blind mole rats Spalax (BMR) are small subterranean rodents common in the Middle East. BMR is distinguished by its adaptations to life underground, remarkable longevity (with a maximum documented lifespan of 21 y), and resistance to cancer. Spontaneous tumors have never been observed in spalacids. To understand the mechanisms responsible for this resistance, we examined the growth of BMR fibroblasts in vitro of the species Spalax judaei and Spalax golani. BMR cells proliferated actively for 7–20 population doublings, after which the cells began secreting IFN-β, and the cultures underwent massive necrotic cell death within 3 d. The necrotic cell death phenomenon was independent of culture conditions or telomere shortening. Interestingly, this cell behavior was distinct from that observed in another long-lived and cancer-resistant African mole rat, Heterocephalus glaber, the naked mole rat in which cells display hypersensitivity to contact inhibition. Sequestration of p53 and Rb proteins using SV40 large T antigen completely rescued necrotic cell death. Our results suggest that cancer resistance of BMR is conferred by massive necrotic response to overproliferation mediated by p53 and Rb pathways, and triggered by the release of IFN-β. Thus, we have identified a unique mechanism that contributes to cancer resistance of this subterranean mammal extremely adapted to life underground. PMID:23129611

A systematic review of taeniasis, cysticercosis and trichinellosis in Vietnam.

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Ng-Nguyen, Dinh; Stevenson, Mark A; Traub, Rebecca J

2017-03-21

Taeniasis, cysticercosis and trichinellosis have been ranked as the most important food-borne parasites of humans in terms of public health, socioeconomic and trade impact. Despite this, information on these food-borne zoonoses in Vietnam is scarce and fragmented, and many local reports remain inaccessible to the international research community. This study aims to conduct comprehensive literature searches to report on the incidence and estimate the true prevalence of taeniasis in humans and T. solium cysticercosis in humans and pigs in Vietnam utilizing Bayesian models; in addition, to report the incidence and the distribution of trichinellosis. A Bayesian approach was used to estimate the true prevalence of taeniasis and cysticercosis based on published diagnostic test characteristics used in each published cross-sectional survey. The utilization of coproscopic-based examination of Taenia eggs in stool, although highly specific for genus-level detection, has poor sensitivity and led to an underestimation of the prevalence of human taeniasis. Similarly, post-mortem-based surveys of T. solium cysticercosis in pigs also led to the underestimation of prevalence of porcine cysticercosis. On the other hand, the low specificity of immunodiagnostic methods, in particular Ab-ELISA, led to a likely overestimation of T. solium cysticercosis in humans. Due to the use of imperfect diagnosis tests combined with poor descriptions of sampling methods, our ability to draw solid conclusions from these data is limited. We estimate that the true prevalence of taeniasis and T. solium cysticercosis in rural 'hotspots', is as high as 13% for each, in humans. Taeniasis and T. solium cysticercosis occurs in 60 of the 63 provinces of Vietnam. Most of the information relating to the distribution and prevalence of porcine cysticercosis is limited to commercial abattoir surveys. In Vietnam, Taenia asiatica appears to be confined to the north where it occurs sympatrically with T. solium and

Exploring Vietnam's oil potential

International Nuclear Information System (INIS)

Anon.

1993-01-01

A brief review is given of the oil production potential in Vietnam. Since Since 1987, the country has been open to foreign investment in offshore exploration but has suffered from a US embargo on trade and economic ties. Nevertheless some exploration has occurred and twenty production sharing contracts with international oil companies has been signed. To date most of the finds have been non-commercial but optimism remains high. (U.K.)

Vietnamese infant and childhood mortality in relation to the Vietnam War.

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Savitz, D A; Thang, N M; Swenson, I E; Stone, E M

1993-08-01

There is obvious potential for war to adversely affect infant and childhood mortality through direct trauma and disruption of the societal infrastructure. This study examined trends in Vietnam through the period of the war. The 1988 Vietnam Demographic and Health Survey collected data on reproductive history and family planning from 4172 women aged 15 through 49 years in 12 selected provinces of Vietnam. The 13,137 births and 737 deaths to children younger than age 6 reported by the respondents were analyzed. For the country as a whole, infant and childhood mortality dropped by 30% to 80% from the prewar period to the wartime period and was stable thereafter. In provinces in which the war was most intense, mortality did not decline from the prewar period to the wartime period but declined after the war, consistent with an adverse effect during the wartime period. The data are limited by assignment of birth location on the basis of mother's current residence and by inadequate information on areas of war activity. Nonetheless, the data do not indicate a widespread, sizable adverse effect of the war on national infant and childhood mortality in Vietnam but suggest detrimental effects in selected provinces.

Clinical microbiology during the Vietnam War.

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Washington, Michael; Brown, Matthew; Palys, Thomas; Tyner, Stuart; Bowden, Robert

2009-11-01

During the period of 1965-1968, over two dozen Army microbiologists were deployed to various locations in Southeast Asia in support of the Vietnam War. Their role was to serve both a clinical laboratory mission/function at the mobile Army surgical hospital and mobile laboratory level as well as to perform research roles in all of the facilities. They were essential to the formulation of medical intelligence as well as to the practice of operational medicine in the deployed environment. The results of their laboratory investigations provided commanders and military physicians with critical medical information for patient care, outbreak investigation, and forensic analysis. As with many soldiers in support of the infantry and armor combat forces, most of the work occurs behind the scenes and their contributions are often left out of the historical literature. This article presents a brief overview of microbiology performed by Army microbiologists during the Vietnam War.

The Educational Realities of Hmong Communities in Vietnam: The Voices of Teachers

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Lavoie, Constance

2011-01-01

This article presents the language policy and sociolinguistic realities of Hmong people in Lao Cai province, Vietnam. Minority children, who have their own mother tongue, are educated in Vietnamese, a language that few understand. In response to this situation, the Ministry of Education and Training of Vietnam in collaboration with UNICEF,…

Caulder's Story: "Chinese Handcuffs" and the Untold Story of the Vietnam War.

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Philion, Thomas

2001-01-01

Calls attention to an important instructional resource that high school English and history teachers can use to engage their students in critical thinking about the Vietnam War. Gives some ideas for helping teenagers to make connections between the young adult novel "Chinese Handcuffs" and the Vietnam War. Suggests the integration of "Chinese…

Antidumping, countervailing duties and non-market economy status of Vietnam in the WTO

OpenAIRE

Claudio Dordi

2008-01-01

The non-market economy status has a negative influence on the international trade relations of Vietnam. The article analyses the legal consequences for Vietnam of the NME status and identify the roadmap to obtain the "market economy status" from other WTO members

Air Freight Service Development Plan : Case: CMA CGM Logistics Vietnam

OpenAIRE

Nguyen, Giang

2014-01-01

Being one of the fastest-growing nations in the world, Vietnam is trading across the border actively and at the same time attracting multiple foreign investments. Import and export activities are occurring vigorously which leads to a huge potential for international transportation sectors, particularly for aviation industry. Hence, the ultimate goal of this thesis is to establish a development plan of air freight service for the case company – CMA CGM Logistics Vietnam (CCLOG VN). The stu...

Child and Family Factors Associated With Child Maltreatment in Vietnam

OpenAIRE

Tran, N.K. (Nhu K.); van Berkel, S.R. (Sheila R.); IJzendoorn, Rien; Alink, Lenneke R.A.

2018-01-01

textabstractThis study aims to explore possible risk factors for child maltreatment in Vietnam by investigating the association of child and family factors with different types of child maltreatment (i.e., sexual abuse, physical abuse, emotional abuse, witnessing parental conflict, and neglect) and the occurrence of multiple types of child maltreatment. Cross-sectional data of 1,851 secondary and high school students aged 12 to 17 years (47.3% boys) in four provinces of Northern Vietnam were ...

Natural radioactivity and external dose assessment of surface soils in Vietnam

International Nuclear Information System (INIS)

Huy, N. Q.; Hien, P. D.; Luyen, T. V.; Hoang, D. V.; Hiep, H. T.; Quang, N. H.; Long, N. Q.; Nhan, D. D.; Binh, N. T.; Hai, P. S.; Ngo, N. T.

2012-01-01

In this study, natural radioactivity in surface soils of Vietnam and external dose assessment to human population, deduced from activities of 226 Ra, 232 Th and 40 K nuclides, were determined. From 528 soil samples collected in 63 provinces of Vietnam, including five centrally governed cities, the average activities were obtained and equal to 42.77 ± 18.15 Bq kg -1 for 226 Ra, 59.84 ± 19.81 Bq kg -1 for 232 Th and 411.93 ± 230.69 Bq kg -1 for 40 K. The outdoor absorbed dose rates (OADRs) in air at 1 m above the ground level for 63 provinces were calculated, and their average value was 71.72 ± 24.72 nGy h -1 , with a range from 17.45 to 149.40 nGy h -1 . The population-weighted OADR of Vietnam was 66.70 nGy h -1 , which lies in the range of 18-93 nGy h -1 found in the World. From the OADRs obtained, it was estimated that the outdoor annual effective dose and indoor annual effective dose to the population were 0.082 and 0.458 mSv, which are higher than the corresponding values 0.07 and 0.41 mSv, respectively, of the World. The radium equivalent activity Ra eq and the external hazard index H ex of surface soils of Vietnam are lower than the corresponding permissible limits of 370 Bq kg -1 and 1, respectively. Therefore, soil from Vietnam is safe for the human population when it is used as a building material. (authors)

Natural Radioactivity and External Dose Assessment of Surface Soils in Vietnam

International Nuclear Information System (INIS)

Huy, N.Q.; Hien, P.D.; Hoang, D.V.; Quang, N.H.; Long, N.Q.; Binh, N.T.; Hai, P.S.

2012-01-01

In this study, natural radioactivity in surface soils of Vietnam and external dose assessment to human population, deduces from activities of 226 Ra, 232 Th and 40 K nuclides, were determined. From 528 soil samples collected in 63 provinces of Vietnam, including five centrally governed cities, the average activities were obtained and equal to 42.77 ± 18.15 Bq kg -1 for 226 Ra, 59.84 ± 19.81 Bq kg -1 for 232 Th and 411.93 ± 230.69 Bq kg -1 for 40 K. The outdoor absorbed dose rates (OADRs) in air at 1 m above the ground level for 63 provinces were calculated, and their average value was 71.72 ± 24.72 nGy h -1 , with a range from 17.45 to 149.40 nGy h -1 . The population-weighted OADR of Vietnam was 66.70 nGy h -1 , which lies in the range of 18-93 nGy h -1 found in the World. From the OADR obtained, it was estimated that the outdoor annual effective dose and indoor annual effective dose to the population were 0.082 and 0.458 mSv, which are higher than the corresponding values 0.07 and 0.41 mSv, respectively, of the World. The radium equivalent activity Ra eq and the external hazard index H ex of surface soils of Vietnam are lower than the corresponding permissible limits of 370 Bq kg -1 and 1, respectively. Therefore, soil from Vietnam is safe for the human population when it used as a building material. (author)

Joint KAERI/VAEC pre-possibility study on a new research reactor for Vietnam

Energy Technology Data Exchange (ETDEWEB)

Park, Cheol; Lee, B. C.; Chae, H. T.; Kim, H.; Lee, C. S.; Choi, C. O.; Jun, B. J. [KAERI, Taejon (Korea, Republic of); Vien, Luong Ba; Dien, Nguyen Nhi [Vietnam Atomic Energy Commission, Hanoi (Viet Nam)

2004-05-01

Based on the agreement on the technical cooperation for nuclear technology between Korea and Vietnam, a KAERI/VAEC joint study on the pre-possibility of a new research reactor for Vietnam has been carried out in the research reactor area from Nov. 2003 to May 2004. In this report, the results of the pre-possibility study on a new research reactor are described. The report presents the necessity of a new research reactor in Vietnam, and the desired performance requirements of the new research reactor if necessary. The major design characteristics of some existing research reactors and those under planning were also reviewed and the main characteristics which should be considered in selecting a new multipurpose research reactor for Vietnam were drawn. Some recommendations on the considerations for the next step of the feasibility study such as the project formulation, manpower requirements and international co-operation were also briefly touched upon.

Joint KAERI/VAEC pre-possibility study on a new research reactor for Vietnam

International Nuclear Information System (INIS)

Park, Cheol; Lee, B. C.; Chae, H. T.; Kim, H.; Lee, C. S.; Choi, C. O.; Jun, B. J.; Vien, Luong Ba; Dien, Nguyen Nhi

2004-05-01

Based on the agreement on the technical cooperation for nuclear technology between Korea and Vietnam, a KAERI/VAEC joint study on the pre-possibility of a new research reactor for Vietnam has been carried out in the research reactor area from Nov. 2003 to May 2004. In this report, the results of the pre-possibility study on a new research reactor are described. The report presents the necessity of a new research reactor in Vietnam, and the desired performance requirements of the new research reactor if necessary. The major design characteristics of some existing research reactors and those under planning were also reviewed and the main characteristics which should be considered in selecting a new multipurpose research reactor for Vietnam were drawn. Some recommendations on the considerations for the next step of the feasibility study such as the project formulation, manpower requirements and international co-operation were also briefly touched upon

The Vital Role of Basic Mathematics in Teaching and Learning the Mole Concept

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Mehrotra, Alka; Koul, Anjni

2016-01-01

This article focuses on the importance of activity-based teaching in understanding the mole concept and the vital role of basic mathematical operations. It describes needs-based training for teachers in a professional development programme in India. Analysis of test results before and after the training indicates that teachers improved their…

Naked mole-rats maintain healthy skeletal muscle and Complex IV mitochondrial enzyme function into old age.

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Stoll, Elizabeth A; Karapavlovic, Nevena; Rosa, Hannah; Woodmass, Michael; Rygiel, Karolina; White, Kathryn; Turnbull, Douglass M; Faulkes, Chris G

2016-12-19

The naked mole-rat (NMR) Heterocephalus glaber is an exceptionally long-lived rodent, living up to 32 years in captivity. This extended lifespan is accompanied by a phenotype of negligible senescence, a phenomenon of very slow changes in the expected physiological characteristics with age. One of the many consequences of normal aging in mammals is the devastating and progressive loss of skeletal muscle, termed sarcopenia, caused in part by respiratory enzyme dysfunction within the mitochondria of skeletal muscle fibers. Here we report that NMRs avoid sarcopenia for decades. Muscle fiber integrity and mitochondrial ultrastructure are largely maintained in aged animals. While mitochondrial Complex IV expression and activity remains stable, Complex I expression is significantly decreased. We show that aged naked mole-rat skeletal muscle tissue contains some mitochondrial DNA rearrangements, although the common mitochondrial DNA deletions associated with aging in human and other rodent skeletal muscles are not present. Interestingly, NMR skeletal muscle fibers demonstrate a significant increase in mitochondrial DNA copy number. These results have intriguing implications for the role of mitochondria in aging, suggesting Complex IV, but not Complex I, function is maintained in the long-lived naked mole rat, where sarcopenia is avoided and healthy muscle function is maintained for decades.

Connecting Vietnam's isolated communities to improve healthcare ...

International Development Research Centre (IDRC) Digital Library (Canada)

2018-01-29

Jan 29, 2018 ... Connecting Vietnam's isolated communities to improve healthcare ... of pregnancy and new motherhood improved their interactions with health workers. ... Return to main page: Overcoming eHealth challenges with social and ...

Systematic review on irrational use of medicines in China and Vietnam.

Directory of Open Access Journals (Sweden)

Wenhui Mao

Full Text Available Irrational use of medicines has been an issue concerned all over the world and the outlooks in developing countries are more severe. This study aimed to assess the different patterns of irrational use of medicines and its influential factors in China and Vietnam.A systematic review was performed on both published and grey literatures in English, Chinese and Vietnamese languages between 1993 and 2013 based on the WHO framework. Quality assessment was conducted on the basis of the Critical Appraisal Skills Programme. Key indicators were analyzed to compare the irrational use of medicines in two countries.A total of 67 published works about China and 29 about Vietnam were included, the majority of which were cross-sectional prescription studies in both China and Vietnam. Irrational use of medicines was found in both the countries but issues with polypharmacy as well as overuse of antibiotics were more severe in Vietnam while overuse of injections was unique to China. Various patterns of irrational use were also indicated between urban and rural areas, and among different levels of hospitals. Rarely does literature focus on the analysis of influential factors of irrational use of medicines. While lack of proper knowledge from both providers and patients were the most recognized influential factors in both countries, economic incentives from pharmaceutical companies in China, and weak control and regulation over prescriptions in Vietnam were the main factors attributed to this issue.Severe irrational use of medicines has been abundantly evidenced in both China and Vietnam, highlighting the importance of policy interventions on the issue. However, limited evidence on the appropriateness or its compliance (conformity to guidelines of prescription has been found. In addition, convincing evidence on the underlying explanation of this issue is lacking, although economic incentives, health insurance coverage, and knowledge of service providers and users

76 FR 68208 - Circular Welded Carbon-Quality Steel Pipe From India, Oman, United Arab Emirates, and Vietnam...

Science.gov (United States)

2011-11-03

... (Preliminary)] Circular Welded Carbon-Quality Steel Pipe From India, Oman, United Arab Emirates, and Vietnam... carbon-quality steel pipe from India, Oman, United Arab Emirates, and Vietnam, provided for in... Governments of India, Oman, United Arab Emirates, and Vietnam. Unless the Department of Commerce extends the...

Mobile Health Initiatives in Vietnam: Scoping Study.

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Lam, Jeffrey A; Dang, Linh Thuy; Phan, Ngoc Tran; Trinh, Hue Thi; Vu, Nguyen Cong; Nguyen, Cuong Kieu

2018-04-24

Mobile health (mHealth) offers a promising solution to the multitude of challenges the Vietnamese health system faces, but there is a scarcity of published information on mHealth in Vietnam. The objectives of this scoping study were (1) to summarize the extent, range, and nature of mHealth initiatives in Vietnam and (2) to examine the opportunities and threats of mHealth utilization in the Vietnamese context. This scoping study systematically identified and extracted relevant information from 20 past and current mHealth initiatives in Vietnam. The study includes multimodal information sources, including published literature, gray literature (ie, government reports and unpublished literature), conference presentations, Web-based documents, and key informant interviews. We extracted information from 27 records from the electronic search and conducted 14 key informant interviews, allowing us to identify 20 mHealth initiatives in Vietnam. Most of the initiatives were primarily funded by external donors (n=15), while other initiatives were government funded (n=1) or self-funded (n=4). A majority of the initiatives targeted vulnerable and hard-to-reach populations (n=11), aimed to prevent the occurrence of disease (n=12), and used text messaging (short message service, SMS) as part of their intervention (n=14). The study revealed that Vietnamese mHealth implementation has been challenged by factors including features unique to the Vietnamese language (n=4) and sociocultural factors (n=3). The largest threats to the popularity of mHealth initiatives are the absence of government policy, lack of government interest, heavy dependence on foreign funding, and lack of technological infrastructure. Finally, while current mHealth initiatives have already demonstrated promising opportunities for alternative models of funding, such as social entrepreneurship or private business models, sustainable mHealth initiatives outside of those funded by external donors have not yet been

Molecular diversity of Rice grassy stunt virus in Vietnam.

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Ta, Hoang-Anh; Nguyen, Doan-Phuong; Causse, Sandrine; Nguyen, Thanh-Duc; Ngo, Vinh-Vien; Hébrard, Eugénie

2013-04-01

Rice grassy stunt virus (RGSV, Tenuivirus) recently emerged on rice in Vietnam, causing high yield losses during 2006-2009. The genetic diversity of RGSV is poorly documented. In this study, the two genes encoded by each ambisense segment RNA3 and RNA5 of RGSV isolates from six provinces of South Vietnam were sequenced. P3 and Pc3 (RNA3) have unknown function, P5 (RNA5) encodes the putative silencing suppressor, and Pc5 (RNA5) encodes the nucleocapsid protein (N). The sequences of 17 Vietnamese isolates were compared with reference isolates from North and South Philippines. The average nucleotide diversity among the isolates was low. We confirmed a higher variability of RNA3 than RNA5 and Pc3 than P3. No relationships between the genetic diversity and the geographic distribution of RGSV isolates could be ascertained, likely because of the long-distance migration of the insect vector. This data will contribute to a better understanding on the RGSV epidemiology in South Vietnam, a prerequisite for further management of the disease and rice breeding for resistance.

Serpents in jars: the snake wine industry in Vietnam

Directory of Open Access Journals (Sweden)

R. Somaweera

2010-10-01

Full Text Available Exploitation of snakes in Vietnam takes place for different purposes, and among them the snake wine industry is prominent but has received far less attention than other dealings, such as the pet trade. Despite widespread commercialisation there is a general lack of information about this snake trade, which makes it difficult to evaluate its magnitude and impact on snake populations. This study documents the use of snakes in snake wine in four cities in Vietnam through surveys conducted in 127 locations selling snake wine in September 2009. This study provides a list of species used along with the number of individuals observed. While none of the species involved are listed in the IUCN Red List, seven species are listed in the Vietnam Red Data Book, of which five are regulated by CITES. On the other hand, the most abundant species used in the trade, Xenochrophis flavipunctatus, is not listed in any conservation document. The popularity and economic importance of snakes in the form of snake wine demonstrates the need for the development of sustainable use programs for these species.

Molecular diagnosis of an ocular toxocariasis patient in Vietnam.

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Van De, Nguyen; Trung, Nguyen Vu; Duyet, Le Van; Chai, Jong-Yil

2013-10-01

An ocular Toxocara canis infection is reported for the first time in Vietnam. A 34-year-old man residing in a village of Son La Province, North Vietnam, visited the National Eye Hospital (NEH) in August 2011. He felt a bulge-sticking pain in his left eye and loss of vision occurred over 3 months before visiting the hospital. The eye examination in the hospital showed damage of the left eye, red eye, retinal fibrosis, retinal detachment, inflammation of the eye tissues, retinal granulomas, and a parasitic cyst inside. A larva of Toxocara was collected with the cyst by a medical doctor by surgery. Comparison of 264 nucleotides of internal transcribed spacer 2 (ITS2) of ribosomal DNA was done between our Vietnamese Toxocara canis and other Toxocara geographical isolates, including Chinese T. canis, Japanese T. canis, Sri Lankan T. canis, and Iranian T. canis. The nucleotide homology was 97-99%, when our T. canis was compared with geographical isolates. Identification of a T. canis infection in the eye by a molecular method was performed for the first time in Vietnam.

Networking Alone? Digital Communications and Collective Action in Vietnam

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Sandra Kurfürst

2015-01-01

Full Text Available This article explores the potential for the formation of collective action in Vietnam. Referring to land and labour protests, bauxite mining, anti-China demonstrations, as well as the revision of the 1992 Constitution, the article examines the social movement repertoires diverse groups have adopted to reach their objectives. Drawing on social movement theory and communication power, this contribution shows that apart from access to the technology, citizens’ opportunities to participate in digital networks as well as access to the default communication network of the state are necessary prerequisites in order to attain public attention and possibly to achieve social change. Moreover, this article shows that existing power differentials in Vietnam are reproduced in digital space. It concludes that for different collective behaviours to result in a social movement, it is essential to “switch” and to connect the different networks. For the moment, the call to protect Vietnam’s sovereignty offers common ground for collective action.

Land surface and climate parameters and malaria features in Vietnam

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Liou, Y. A.; Anh, N. K.

2017-12-01

Land surface parameters may affect local microclimate, which in turn alters the development of mosquito habitats and transmission risks (soil-vegetation-atmosphere-vector borne diseases). Forest malaria is a chromic issue in Southeast Asian countries, in particular, such as Vietnam (in 1991, approximate 2 million cases and 4,646 deaths were reported (https://sites.path.org)). Vietnam has lowlands, sub-tropical high humidity, and dense forests, resulting in wide-scale distribution and high biting rate of mosquitos in Vietnam, becoming a challenging and out of control scenario, especially in Vietnamese Central Highland region. It is known that Vietnam's economy mainly relies on agriculture and malaria is commonly associated with poverty. There is a strong demand to investigate the relationship between land surface parameters (land cover, soil moisture, land surface temperature, etc.) and climatic variables (precipitation, humidity, evapotranspiration, etc.) in association with malaria distribution. GIS and remote sensing have been proven their powerful potentials in supporting environmental and health studies. The objective of this study aims to analyze physical attributes of land surface and climate parameters and their links with malaria features. The outcomes are expected to illustrate how remotely sensed data has been utilized in geohealth applications, surveillance, and health risk mapping. In addition, a platform with promising possibilities of allowing disease early-warning systems with citizen participation will be proposed.

How might the Trans-Pacific Partnership impact on the pharmaceutical sector in Vietnam?

Science.gov (United States)

Binh, Nguyen Hoa; Anh, Pham Ngoc Kieu; Phuong, Nguyen Minh

2016-07-01

Ratification of the Trans-Pacific Partnership (TPP) will attract a large number of foreign drug companies in the coming years to Vietnam. It is anticipated to bring investment to Vietnam's pharmaceutical industries, lead to increased infrastructure and enable the use of more sophisticated technologies for the discovery, development and manufacture of drugs. However, with respect to pharmaceutical companies, which are producing generic drugs primarily, the availability of biologic will be reduced. Thus, the consequence is, an increase in drug cost resulting in difficulties for patients wishing to procure these drugs. This will be particularly detrimental for developing countries, such as Vietnam and Malaysia.

Globalization Crises, Trade,and Development in Vietnam

DEFF Research Database (Denmark)

Abbott, Philip; Tarp, Finn

Vietnam has been among the most successful East Asian economies, especially in weathering the external shocks of recent globalization crises—the 1997-98 Asian financial crisis and the 2008-09 great recession, financial crisis and collapse of global trade. Its success contradicts its characterizat......Vietnam has been among the most successful East Asian economies, especially in weathering the external shocks of recent globalization crises—the 1997-98 Asian financial crisis and the 2008-09 great recession, financial crisis and collapse of global trade. Its success contradicts its...... that dependence and bolster the domestic economy while continuing to restructure the economy toward greater emphasis on the private sector. Growth, employment and poverty alleviation have been maintained at the expense of renewed inflation, larger budget deficits, and currency depreciation. The ‘stop-go’ nature...

[The current situation and agendas in the prevention and control of non-communicable diseases in Vietnam].

Science.gov (United States)

Hattori, Kiyoko; Uda, Hidenori; Hitomi, Yoshiaki; Yano, Ryosuke; Saijo, Takao; Watanabe, Naoyuki; Satomi, Maki; Yoshida, Aya; Oishi, Osamu; Yamashita, Tsuyoshi; Kamenosono, Akira

2018-01-01

Objectives　In Vietnam, the number of patients with non-communicable diseases (NCDs) has been increasing in recent years in association with the country's remarkable economic growth and corresponding changes in its population's lifestyle. The purposes of this research were to identify the challenges in the prevention and control of NCDs in Vietnam and to discuss countermeasures for NCDs in Vietnam and Japan.Methods　As a 2015 Regional Public Health Overall Promotion Project, an investigation team consisting of 11 public health physicians visited Hanoi, the capital of Vietnam, and its vicinities from January 11, 2016 to January 15, 2016. In Hanoi and its vicinities, we visited local healthcare institutions, such as the World Health Organization(WHO) Representative Office in Vietnam and Ministry of Health of Vietnam, and discussed the prevention and control of NCDs in Vietnam and Japan.Results　According to a survey in 2014, 73% of people of all age groups in Vietnam died from NCDs and the number of people suffering from NCDs has been sharply increasing in recent years. Major behavioral risk factors are dietary risks, tobacco smoke, alcohol use, and physical inactivity. There are four main problems with prevention and control of NCDs: 1) low awareness among the people of NCDs, 2) regional disparity of medical services, 3) shortage of healthcare staff members with professional knowledge, and 4) poor NCD surveillance.　In Vietnam, an NCD program with screening methods and medical guidelines for respective diseases was developed in 2002. However, it only covered tertiary prevention and did not fully describe the primary and secondary prevention measures. Currently, with the technical assistance of the WHO, the implementation of countermeasures emphasizing prevention and control to reduce NCD risk factors has only just begun.Conclusion　It was considered that educating each person in Vietnam on NCD prevention measures would be necessary and that a national policy

TET Offensive II Field Force Vietnam After Action Report 31 January - 18 February 1968

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1968-03-01

and the 5th VC Division. V During this same period of time there were no majur shifts in ARVN forces . However III Corps shifted three...8217-".•: ’ ’SSIFJED U.S. ARMY. VIETNAM. II FIELD FORCE . TET OFFENSIVE II FIELD FORCE VIETNAM AFTER ACTION REPORT, 31 JANUARY-18 FEB- RUARY 1968...H FIELD FORCE VIETNAM AFTER ACTION REPORT 31 January-18 February 1968 RECORD K0- ! FlSjl fi-.-A-,>-•: it tT*\\ : *si h s» -wP Mr-, £< St