WorldWideScience

Sample records for modulated radio-over-fibre links

  1. Digital coherent receiver employing photonic downconversion for phase modulated radio-over-fibre links

    DEFF Research Database (Denmark)

    Zibar, Darko; Caballero Jambrina, Antonio; Guerrero Gonzalez, Neil

    2009-01-01

    A digital coherent receiver employing photonic downconversion is presented and experimentally demonstrated for phase-modulated radio-over-fibre optical links. The receiver is capable of operating at frequencies exceeding the bandwidth of electrical analog-to-digital converter by using photonic...... downconversion to translate the high-frequency input RF signal to the operating frequency range of the analog-to-digital converter. First, using linear digital demodulation scheme we measure SFDR of the link at microwave frequency of 5 GHz. Thereafter, successful signal demodulation of 50 Mbit/s binary phase...... shift keying (BPSK) modulated data signal at 5 GHz RF carrier frequency is experimentally demonstrated by using an analog-to-digital converter with only 1 GHz bandwidth. We successfully demonstrate signal demodulation, using the proposed digital coherent receiver with photonic downconversion, after 40...

  2. Experimental 2.5 Gbit/s QPSK WDM coherent phase modulated radio-over-fibre link with digital demodulation by a K-means algorithm

    DEFF Research Database (Denmark)

    Guerrero Gonzalez, Neil; Caballero Jambrina, Antonio; Amaya Fernández, Ferney Orlando

    2009-01-01

    Highest reported bit rate of 2.5 Gbit/s for optically phase modulated radio-over-fibre link employing coherent detection is demonstrated. Demodulation of 3·2.5 Gbit/s QPSK modulated WDM channels, is achieved after 79km of transmission through deployed fiber.......Highest reported bit rate of 2.5 Gbit/s for optically phase modulated radio-over-fibre link employing coherent detection is demonstrated. Demodulation of 3·2.5 Gbit/s QPSK modulated WDM channels, is achieved after 79km of transmission through deployed fiber....

  3. Digital coherent receiver for phase modulated radio-over-fibre optical links

    DEFF Research Database (Denmark)

    Zibar, Darko; Yu, Xianbin; Peucheret, Christophe

    2009-01-01

    A novel digital signal processing-based coherent receiver for phase-modulated radio-over-fiber (RoF) optical links is presented and demonstrated experimentally. Error-free demodulation of 50-Mbaud binary phase-shift keying (BPSK) and quadrature phase-shift keying data signal modulated on a 5-GHz...... radio-frequency (RF) carrier is experimentally demonstrated using the proposed digital coherent receiver. Additionally, a wavelength-division-multiplexing (WDM) phase-modulated RoF optical link is experimentally demonstrated. A 3 x50 Mb/s WDM transmission of a BPSK modulated 5-GHz RF carrier is achieved...... over 25 km for the WDM channel spacing of 12.5 and 25 GHz, respectively....

  4. Coherent Detection of Wavelength Division Multiplexed Phase-Modulated Radio-over-Fibre Signals

    DEFF Research Database (Denmark)

    Zibar, Darko; Yu, Xianbin; Peucheret, Christophe

    2008-01-01

    A WDM phase-modulated Radio-over-Fibre link using digital coherent detection is experimentally demonstrated. 3 times 50 Mb/s WDM transmission of a BPSK modulated 5 GHz RF carrier is achieved over 25 km.......A WDM phase-modulated Radio-over-Fibre link using digital coherent detection is experimentally demonstrated. 3 times 50 Mb/s WDM transmission of a BPSK modulated 5 GHz RF carrier is achieved over 25 km....

  5. Digital coherent receiver for subcarrier multiplexed phase modulated radio-over-fibre signals

    DEFF Research Database (Denmark)

    Zibar, Darko; Larsen, Knud J.; Tafur Monroy, Idelfonso

    2009-01-01

    Digital coherent detection of multi-channel subcarrier multiplexed optically phase-modulated radio-over-fibre signals is experimentally demonstrated. Successful detection after transmission over a 40 km long fibre link of four or five 25 Mbaud BPSK/QPSK subcarrier channels in 5 GHz bandwidth...... is demonstrated using offline digital signal processing....

  6. Experimental demonstration of a digital maximum likelihood based feedforward carrier recovery scheme for phase-modulated radio-over-fibre links

    DEFF Research Database (Denmark)

    Guerrero Gonzalez, Neil; Zibar, Darko; Yu, Xianbin

    2008-01-01

    Maximum likelihood based feedforward RF carrier synchronization scheme is proposed for a coherently detected phase-modulated radio-over-fiber link. Error-free demodulation of 100 Mbit/s QPSK modulated signal is experimentally demonstrated after 25 km of fiber transmission.......Maximum likelihood based feedforward RF carrier synchronization scheme is proposed for a coherently detected phase-modulated radio-over-fiber link. Error-free demodulation of 100 Mbit/s QPSK modulated signal is experimentally demonstrated after 25 km of fiber transmission....

  7. Combined Transmission of Baseband NRZ-DQPSK and Phase Modulated Radio-over-Fibre

    DEFF Research Database (Denmark)

    Jensen, Jesper Bevensee; Yu, Xianbin; Tafur Monroy, Idelfonso

    2008-01-01

    21.4 Gbit/s baseband DQPSK and 1.25 Gbit/s phase modulated RoF was transmitted over 80 km SSMF using polarization multiplexing.......21.4 Gbit/s baseband DQPSK and 1.25 Gbit/s phase modulated RoF was transmitted over 80 km SSMF using polarization multiplexing....

  8. Linewidth tolerance of digital coherent receiver using Viterbi & Viterbi RF carrier recovery for radio-over-fibre links

    DEFF Research Database (Denmark)

    Guerrero Gonzalez, Neil; Zibar, Darko; Larsen, Knud J.

    2009-01-01

    for phase-modulated RoF optical links (2). The RF signal processing in (2) is performed using maximum likelihood RF carrier phase estimation (2). In this paper, we investigate the performance of the proposed digital coherent receiver in (2) using feedforward Viterbi & Viterbi RF carrier recovery algorithm...

  9. Wavelet-Coding for Radio over Fibre

    DEFF Research Database (Denmark)

    Cavalcante, Lucas Costa Pereira

    As the fifth generation of mobile communication technology is developed and implemented, worldwide solutions propose the use of much greater spectrum allocations, including the millimetre-wave frequency band. Radioover-fiber (RoF) links allow straight forward integration of the mobile front...

  10. Digital coherent detection of multi-gigabit 40 GHz carrier frequency radio-over-fibre signals using photonic downconversion

    DEFF Research Database (Denmark)

    Caballero Jambrina, Antonio; Zibar, Darko; Tafur Monroy, Idelfonso

    2010-01-01

    Detection of high-speed radio signals is a challenge for next generation radio-over-fibre links, requiring high bandwidth and linearity in the receiver. By using photonic downconversion in a coherent receiver, detection of high bit-rate 16-QAM signals, up to 4 Gbit/s, at a 40 GHz carrier frequency...

  11. Cognitive digital receiver for burst mode phase modulated radio over fiber links

    DEFF Research Database (Denmark)

    Guerrero Gonzalez, Neil; Zibar, Darko; Tafur Monroy, Idelfonso

    2010-01-01

    A novel cognitive receiver for modulation format recognition with reconfigurable carrier recovery scheme is proposed and experimentally demonstrated for phase modulated radio-over-fibre links. Demodulation of burst-mode mixed modulation formats (PSK and QAM) is demonstrated after 40km...

  12. Effect of the degree of phase-correlation of laser sources on the transmission and optical coherent detection in radio-over-fibre systems

    Science.gov (United States)

    Maldonado-Basilio, Ramón; Li, Ran; Abdul-Majid, Sawsan; Nikkhah, Hamdam; Leong, Kin-Wai; Hall, Trevor J.

    2013-01-01

    The deployment of high capacity Radio-over-Fiber (RoF) systems rely, among many aspects, on the capability to efficiently generate, transport, and detect millimeter-wave carriers modulated at high data rates. Photonic approaches based on the heterodyne beating of two free-running laser sources have been proposed as an alternative to generate multi-Gbps quadrature phase modulated signals imposed on millimeter wave carriers. Implementing photonic approaches in the down-link avoids the need for electronic generation of high frequency carriers and decreases the requirements at the base band electronics. In addition, implementing complex modulation formats overcomes some of the typical issues found in intensity modulation direct detection approaches such as non­ linearity, receiver sensitivity and dynamic range. In this work, the performance improvement of a coherent RoF system carrying 10 Gbps QPSK signals is numerically analyzed in terms of both the frequency linewidth and the degree of phase correlation between the lasers utilised at the down-link (for the optical heterodyne beating) and at the up-link (for the optical coherent detection). Relative to phase correlated lasers featuring linewidths of 5 MHz, the peak power of the 60 G Hz carrier generated at the down-link is reduced by 8 dB for un-correlated lasers. In addition, the error vector magnitude of the received signal at the up-link is improved from over 20% (for un-correlated lasers and linewidths of 5 MHz) to around 15% (for correlated lasers) at an optical received power of -30 dBm. The results obtained reinforce the idea of using coherent comb laser sources with phase correlated modes located at the Central Office. It also motivates the eventual deployment of techniques to control the degree of phase correlation between the lasers used as signal and local oscillator at the optical coherent receivers.

  13. Simultaneous optical carrier and radio frequency re-modulation in radio-over-fiber systems employing reflective SOA modulators

    DEFF Research Database (Denmark)

    Kassar, Carvalho; Calabretta, Nicola; Tafur Monroy, Idelfonso

    2007-01-01

    We demonstrate an innovative full-duplex radio-over-fibre transmission system employing a reflective SOA to perform simultaneous reusing of the optical carrier and data re-modulation, thus avoiding the use of local radiofrequency oscillator at the station sites.......We demonstrate an innovative full-duplex radio-over-fibre transmission system employing a reflective SOA to perform simultaneous reusing of the optical carrier and data re-modulation, thus avoiding the use of local radiofrequency oscillator at the station sites....

  14. Polybinary modulation for bandwidth limited optical links

    DEFF Research Database (Denmark)

    Vegas Olmos, Juan José; Jurado-Navas, Antonio

    2015-01-01

    Optical links using traditional modulation formats are reaching a plateau in terms of capacity, mainly due to bandwidth limitations in the devices employed at the transmitter and receivers. Advanced modulation formats, which boost the spectral efficiency, provide a smooth migration path towards...... the recent results on poly binary modulation, comprising both binary and multilevel signals as seed signals. The results will show how poly binary modulation effectively reduces the bandwidth requirements on optical links while providing high spectral efficiency....

  15. High-fidelity angle-modulated analog optical link.

    Science.gov (United States)

    Che, Di; Yuan, Feng; Shieh, William

    2016-07-25

    There has long existed a debate over whether analog or digital optical link is more suitable for wireless convergence applications. Digital link achieves the highest fidelity, with the sacrifice of huge bandwidth due to the high resolution of digitization, and large power consumption due to the exhaustive digital data recovery. Analog link avoids these drawbacks, but it inevitably suffers from the SNR degradation. In this paper, we propose the angle modulation for analog optical link, which successfully breaks the SNR ceiling of amplitude modulation, and achieves ultrahigh link fidelity. Using the digital link (CPRI) equivalent bandwidth, angle modulation exhibits around 30-dB SNR advantage over the conventional amplitude modulation. Combined with its high tolerance on link nonlinearity, angle modulation has great potential in the future SNR-hungry analog optical applications.

  16. Challenges in Polybinary Modulation for Bandwidth Limited Optical Links

    DEFF Research Database (Denmark)

    Vegas Olmos, Juan José; Tafur Monroy, Idelfonso; Madsen, Peter

    2016-01-01

    Optical links using traditional modulation formats are reaching a plateau in terms of capacity, mainly due to bandwidth limitations in the devices employed at the transmitter and receivers. Advanced modulation formats, which boost the spectral efficiency, provide a smooth migration path towards...... of the current research status of the key building blocks in polybinary systems. The results clearly show how polybinary modulation effectively reduces the bandwidth requirements on optical links while providing high spectral efficiency....

  17. The BREMSAT Phase-Modulated Communications Link

    OpenAIRE

    Lefevre, Don

    1990-01-01

    BREMSAT is a small scientific satellite being constructed by the west German Zentrum fur angewandte Raumfahrttechnologie und Mikrogravitation (ZARM), at Bremen University. BREMSAT's payload consists of five scientific experiment packages. The satellite is scheduled for Get-Away-Special (GAS) Canister launch during the German D-2 shuttle mission in March 1992. Cynetics Corporation is constructing the TT&C link for the satellite, using its standard CMX9600 modem. This modem is the result of Cyn...

  18. Modulator-Based, High Bandwidth Optical Links for HEP Experiments

    CERN Document Server

    Underwood, D G; Fernando, W S; Stanek, R W

    2012-01-01

    As a concern with the reliability, bandwidth and mass of future optical links in LHC experiments, we are investigating CW lasers and light modulators as an alternative to VCSELs. These links will be particularly useful if they utilize light modulators which are very small, low power, high bandwidth, and are very radiation hard. We have constructed a test system with 3 such links, each operating at 10 Gb/s. We present the quality of these links (jitter, rise and fall time, BER) and eye mask margins (10GbE) for 3 different types of modulators: LiNbO3-based, InP-based, and Si-based. We present the results of radiation hardness measurements with up to ~1012 protons/cm2 and ~65 krad total ionizing dose (TID), confirming no single event effects (SEE) at 10 Gb/s with either of the 3 types of modulators. These optical links will be an integral part of intelligent tracking systems at various scales from coupled sensors through intra-module and off detector communication. We have used a Si-based photonic transceiver to...

  19. Photonic Modulation and Demodulation techniques for Multi-Gb/s Millimetre wave Wireless Links

    OpenAIRE

    Sambaraju -, Rakesh

    2011-01-01

    Los sistemas de radio sobre fibra(Radio Over fibre ROF) ofrecen el ancho de banda y flexibilidad necesario para la generación y distribución de del señales inalámbricas del futuro en una arquitectura de red óptica, que reduce el coste de las redes centralizando el procesado y simplificando la ubicación de la antena (estación de base EB). El uso de sistemas de comunicaciones ópticas como una media de transporte de señales inalámbricas en enlaces RoF reduce el cuello de botella entre los están...

  20. Communicative intentions can modulate the linguistic perception-action link.

    Science.gov (United States)

    Kashima, Yoshihisa; Bekkering, Harold; Kashima, Emiko S

    2013-08-01

    Although applauding Pickering & Garrod's (P&G's) attempt to ground language use in the ideomotor perception-action link, which provides an "infrastructure" of embodied social interaction, we suggest that it needs to be complemented by an additional control mechanism that modulates its operation in the service of the language users' communicative intentions. Implications for intergroup relationships and intercultural communication are discussed.

  1. DSP based coherent receiver for phase-modulated radio-over-fiber optical links

    DEFF Research Database (Denmark)

    Zibar, Darko; Tafur Monroy, Idelfonso; Peucheret, Christophe

    2008-01-01

    A novel DSP based coherent receiver for phase modulated radio-over-fiber optical links is reported. Using the proposed digital receiver, signal demodulation of 1.25 Gb/s ASK-modulated 10 GHz RF carrier is experimentally demonstrated.......A novel DSP based coherent receiver for phase modulated radio-over-fiber optical links is reported. Using the proposed digital receiver, signal demodulation of 1.25 Gb/s ASK-modulated 10 GHz RF carrier is experimentally demonstrated....

  2. Down-conversion IM-DD RF photonic link utilizing MQW MZ modulator.

    Science.gov (United States)

    Xu, Longtao; Jin, Shilei; Li, Yifei

    2016-04-18

    We present the first down-conversion intensity modulated-direct detection (IM-DD) RF photonic link that achieves frequency down-conversion using the nonlinear optical phase modulation inside a Mach-Zehnder (MZ) modulator. The nonlinear phase modulation is very sensitive and it can enable high RF-to-IF conversion efficiency. Furthermore, the link linearity is enhanced by canceling the nonlinear distortions from the nonlinear phase modulation and the MZ interferometer. Proof-of-concept measurement was performed. The down-conversion IM-DD link demonstrated 28dB improvement in distortion levels over that of a conventional IM-DD link using a LiNbO3 MZ modulator.

  3. Stability analysis and dynamic response of a DC-link module with a series voltage compensator

    DEFF Research Database (Denmark)

    Wang, Huai; Liu, Wenchao; Chung, Henry

    2013-01-01

    A DC-link module composed of a reduced value of DC-link capacitor and a series voltage compensator has been proposed. The voltage compensator processes the ripple voltage on the DC link and reactive power only, which can be implemented by low-voltage devices. The overall energy storage of the DC...

  4. Design-oriented analytic model of phase and frequency modulated optical links

    Science.gov (United States)

    Monsurrò, Pietro; Saitto, Antonio; Tommasino, Pasquale; Trifiletti, Alessandro; Vannucci, Antonello; Cimmino, Rosario F.

    2016-07-01

    An analytic design-oriented model of phase and frequency modulated microwave optical links has been developed. The models are suitable for design of broadband high dynamic range optical links for antenna remoting and optical beamforming, where noise and linearity of the subsystems are a concern Digital filter design techniques have been applied to the design of optical filters working as frequency discriminator, that are the bottleneck in terms of linearity for these systems. The models of frequency modulated, phase modulated, and coherent I/Q link have been used to compare performance of the different architectures in terms of linearity and SFDR.

  5. Photonic downconversion for coherent phase-modulated radio-over-fiber links using free-running local oscillator

    DEFF Research Database (Denmark)

    Caballero Jambrina, Antonio; Zibar, Darko; Schäffer, Christian G.

    2011-01-01

    A digital coherent receiver employing photonic downconversion is presented and experimentally demonstrated for phase-modulated radio-over-fiber optical links. Photonic downconversion adds additional advantages to optical phase modulated links by allowing demodulation of signals with RF carrier...

  6. 225m Outdoor W-Band Radio-over-Fiber Link Using an Optical SFP+ Module

    DEFF Research Database (Denmark)

    Rommel, Simon; Rodríguez Páez, Juan Sebastián; Chorchos, Łukasz

    2016-01-01

    A W-band radio-over-fiber link based on a commercial SFP+ module is demonstrated, allowing easy integration into existing PON solutions. Without active laser control good RF frequency stability and 225m wireless distance are achieved...

  7. Distribution of DVB-C Channels over an Externally Modulated Optical Link

    Science.gov (United States)

    Andrade, Paulo; Lima, Mário; Teixeira, António

    2012-03-01

    In this paper, we will study, via simulation, the transmission of DVB-C channels over an external modulated optical link using a Mach-Zehnder modulator (MZM). We will also observe the consequences of biasing the MZM near its transmission minimum point, which allows higher carrier to noise ratio at the transmitter, but increases second-order distortion at the receiver.

  8. Dynamic Range Enhancement in Analog Optical Links with a Balanced Modulation and Detection Scheme

    NARCIS (Netherlands)

    Marpaung, D.A.I.; Roeloffzen, C.G.H.; Etten, van W.

    2006-01-01

    A novel noise reduction scheme called Balanced Modulation and Detection (BMD) is proposed. In this scheme, the modulating RF signal is half-wave rectified in the optical domain, eliminating the DC optical power resulting from pre-biasing of the optical source. A link model employing this scheme has

  9. Development of modulation strategies for NPC converter addressing DC link voltage balancing and CMV reduction

    DEFF Research Database (Denmark)

    Boian, D.; Biris, C.; Teodorescu, Remus

    2012-01-01

    in insulation breakdown and bearing failures. By the use of this type of converters, both Electromagnetic Interference (EMI) and harmonic distortions are improved. This paper proposes two modulation strategies for Three Level Neutral Point Clamped Converter (3L-NPC). The main focus of these modulation...... strategies is to reduce the Common Mode Voltage (CMV) and balance the DC Link Voltage....

  10. Double quadriphase modulation/demodulation technique for three-channel communication link. [Space Shuttle-to-TDRS link example

    Science.gov (United States)

    Alem, W. K.

    1977-01-01

    A modulation technique for a three-channel communication link is introduced. The structure of the modulator is such as to form an unbalanced quadriphase signal wherein the high rate data stream is bi-phase modulated on the in-phase carrier component, while the sum of the two lower rate signals is bi-phase modulated on the quadrature component of the same carrier. The sum of the two lower signals is, in turn, formed by modulating with the respective data streams the in-phase and the quadrature components of a square wave subcarrier. At the demodulator, the tracking of the carrier and the subcarrier is performed by two independent Costas loops. The demodulation of the high data rate signal is carried out after establishing the carrier reference signal, while the lower rate signals are demodulated after the subcarrier loop recovers the subcarrier. In this paper, the performance of the two loops is analyzed and the expressions for the tracking errors are derived. Finally, a numerical example pertaining to the Space Shuttle-to-TDRS Ku-band link is presented for illustration.

  11. A method for identifying hierarchical sub-networks / modules and weighting network links based on their similarity in sub-network / module affiliation

    Directory of Open Access Journals (Sweden)

    WenJun Zhang

    2016-06-01

    Full Text Available Some networks, including biological networks, consist of hierarchical sub-networks / modules. Based on my previous study, in present study a method for both identifying hierarchical sub-networks / modules and weighting network links is proposed. It is based on the cluster analysis in which between-node similarity in sets of adjacency nodes is used. Two matrices, linkWeightMat and linkClusterIDs, are achieved by using the algorithm. Two links with both the same weight in linkWeightMat and the same cluster ID in linkClusterIDs belong to the same sub-network / module. Two links with the same weight in linkWeightMat but different cluster IDs in linkClusterIDs belong to two sub-networks / modules at the same hirarchical level. However, a link with an unique cluster ID in linkClusterIDs does not belong to any sub-networks / modules. A sub-network / module of the greater weight is the more connected sub-network / modules. Matlab codes of the algorithm are presented.

  12. Performance Evaluation of Digital Coherent Receivers for Phase-Modulated Radio-Over-Fiber Links

    DEFF Research Database (Denmark)

    Caballero Jambrina, Antonio; Zibar, Darko; Tafur Monroy, Idelfonso

    2011-01-01

    The performance of optical phase-modulated (PM) radio-over-fiber (RoF) links assisted with coherent detection and digital signal processing (PM-Coh) is analyzed and experimentally demonstrated for next-generation wireless-over-fiber systems. PM-Coh offers high linearity for transparent transport......-bandwidth electronics. Analytical assessment and simulations are used to determine the ultimate performance with respect to laser linewidth, modulation index, and receiver sensitivity. Then, two different scenarios are studied and experimentally demonstrated as an application of PM-Coh links: a high...

  13. Free-space optical data link to a small robot using modulating retroreflectors

    Science.gov (United States)

    Rabinovich, William S.; Murphy, James L.; Suite, Michele; Ferraro, Mike; Mahon, Rita; Goetz, Peter; Hacker, Kurt; Freeman, Wade; Saint Georges, Eric; Uecke, Stan; Sender, John

    2009-08-01

    Small robots are finding increasing use for operations in areas that may be dangerous to humans. These robots often have needs for high bandwidth communications to return video and other data. While radio frequency (RF) links can be used in may cases, in some circumstances they may be impractical due to frequency congestion, reflections off surfaces, jamming or other RF noise. In these cases an optical link may be advantageous, particularly when a clear line of sight exists. However, a conventional optical link has limitations for this application. For example, a conventional optical link operating at rates of megabits per second at ranges of 1 Km requires about a 1 degree pointing accuracy. This implies a need for active pointing and tracking, which maybe be unacceptable for a small platform. We explored an optical modulating retroreflector (MRR) link for these cases. An array of 6 MRRs and photodetectors with a field of view of 180 degrees (azimuth)x 30 degrees (elevation) was constructed and mounted a small robot, the iRobot PackbotTM. An Ethernet modem designed to work with MRR links was also part of the system. Using a tracking laser interrogator at the other end of the link, a 1.5 Mbps free space optical Ethernet link was established that completely replaced the normal RF Ethernet link. The link was demonstrated out to ranges of 1 Km down a road, exceeding the range of the RF link. Design issues and measurements of performance will be described.

  14. Outdoor W-Band Hybrid Photonic Wireless Link Based on an Optical SFP+ Module

    DEFF Research Database (Denmark)

    Rommel, Simon; Rodríguez Páez, Juan Sebastián; Chorchos, Łukasz

    2016-01-01

    This letter proposes aW-band hybrid photonic wireless link based on a commercial SFP+ module and experimentally demonstrates its performance. Using a free running laser as local oscillator and heterodyne photonic upconversion, good frequency stability is achieved. Outdoor wireless transmission ov...

  15. Communicative intentions can modulate the linguistic perception-action link [Open Peer Commentary

    NARCIS (Netherlands)

    Kashima, Y.; Bekkering, H.; Kashima, E.S.

    2013-01-01

    Although applauding Pickering & Garrod's (P&G's) attempt to ground language use in the ideomotor perception-action link, which provides an "infrastructure" of embodied social interaction, we suggest that it needs to be complemented by an additional control mechanism that modulates its operation in t

  16. Multiband Carrierless Amplitude Phase Modulation for High Capacity Optical Data Links

    DEFF Research Database (Denmark)

    Iglesias Olmedo, Miguel; Zuo, Tianjian; Jensen, Jesper Bevensee

    2014-01-01

    packaging. Therefore, increasing effort is now put into the possibility of exploiting higher order modulation formats with increased spectral efficiency and reduced optical transceiver complexity. As these type of links are based on intensity modulation and direct detection, modulation formats relying...... on optical coherent detection can not be straight forwardly employed. As an alternative and more viable solution, this paper proposes the use of carrierless amplitude phase (CAP) in a novel multiband approach (MultiCAP) that achieves record spectral efficiency, increases tolerance towards dispersion......Short range optical data links are experiencing bandwidth limitations making it very challenging to cope with the growing data transmission capacity demands. Parallel optics appears as a valid short-term solution. It is, however, not a viable solution in the long-term because of its complex optical...

  17. Evaluation of functional reliability indices for DC-link capacitors in pulse-width modulation converters

    Directory of Open Access Journals (Sweden)

    Gorpinich Alexander

    2017-01-01

    Full Text Available The impact of kHz range harmonics on the power losses, thermal stress, and lifetime reduction of the dc-link capacitors in pulse-width modulation (PWM converters was investigated. Expressions to evaluate the mean time to failure, survival probability, and unavailability of aging failure for dc-link capacitors are presented. The dc-link capacitors failures due to accelerated insulation aging were modeled using Weibull and normal distribution. A case study with the Siemens SINAMICS S120 frequency converter for driving of rolling mill leveler shows that the failures of motor modules due to breakdown of electrolytic dc-link capacitors registered for the time frame from May 2012 to October 2012 can be caused by the increased ambient temperature and additional heating due to high-frequency components of the ripple current. As a possible solution to improve reliability of motor modules, the four AVX FFVE4I0227K film capacitors instead of nine EPCOS B43564 electrolytic capacitors in dc-link were recommended.

  18. Sub-cycle QAM modulation for VCSEL-based optical fiber links

    DEFF Research Database (Denmark)

    Pham, Tien-Thang; Rodes Lopez, Roberto; Jensen, Jesper Bevensee;

    2013-01-01

    QAM modulation utilizing subcarrier frequency lower than the symbol rate is both theoretically and experimentally investigated. High spectral efficiency and concentration of power in low frequencies make sub-cycle QAM signals attractive for optical fiber links with direct modulated light sources....... Real-time generated 10-Gbps 4-level QAM signal in a 7.5-GHz bandwidth utilizing subcarrier frequency at a half symbol rate was successfully transmitted over 20-km SMF using an un-cooled 1.5-μm VCSEL. Only 2.5-dB fiber transmission power penalty was observed with no equalization applied....

  19. Long Lifetime DC-Link Voltage Stabilization Module for Smart Grid Application

    DEFF Research Database (Denmark)

    Wang, Huai; Chung, Henry; Liu, Wenchao

    2012-01-01

    Power converters enable efficient and flexible control and conversion of electric energy among different smart grid players (i.e. producers, energy storage systems, and loads). One of the expected features of smart grid is that it will be more reliable compared to conventional grid. However, power...... converters are one kind of the lifetime limiting components applied in smart grid. One of the major causes is the malfunction of electrolytic capacitors (E-Caps) which are widely used for stabilizing the dc-link voltage in various types of power converters applied in smart grid. A dc-link module is therefore...

  20. DC link current simulation of voltage source inverter with random space vector pulse width modulation

    Directory of Open Access Journals (Sweden)

    Chen Guoqiang

    2016-01-01

    Full Text Available Aiming at analysis complexity, a simulation model is built and presented to analyze and demonstrate the characteristics of the direct current (DC link current of the three-phase two-level inverter with the random space vector pulse width modulation (SVPWM strategy. The developing procedure and key subsystems of the simulation model are given in detail. Several experiments are done using the simulation model. The results verify the efficiency and convenience of the simulation model and show that the random SVPWM scheme, especially the random switching frequency scheme, can efficiently suppress the harmonic peaks of the DC link current.

  1. Linearized Optically Phase-Modulated Fiber Optic Links for Microwave Signal Transport

    Science.gov (United States)

    2009-03-03

    a number of external modulation techniques. For particularly long links, a single or small number of Erbium-Doped Fiber Amplifiers ( EDFA ) could...amplifier (Erbium-Doped Fiber Amplifier, or EDFA ) is present, its noise contribution is caused by beating between the signal and the...the absence of an EDFA , received optical powers that generate photocurrents below approximately 1 mA cause the system noise to be dominated by the

  2. On the Linking Algebra of Hilbert Modules and Morita Equivalence of Locally C*-Algebras

    Directory of Open Access Journals (Sweden)

    Maria Joita

    2006-12-01

    Full Text Available In this paper we introduce the notion of linking algebra of a Hilbert module over a locally C*-algebra and we extend in the context of locally C*-algebras a result of Brown, Green and Rieffel [Pacific J., 1977] which states that two C*-algebras are strongly Morita equivalent if and only if they are isomorphic with two complementary full corners of a C*-algebra.

  3. Photonic aided bandpass sampling in coherent phase modulated radio-over-fiber links

    Science.gov (United States)

    Cao, Minghua; Li, Jianqiang; Dai, Jian; Dai, Yitang; Yin, Feifei; Zhou, Yue; Xu, Kun

    2016-06-01

    We have experimentally presented a digital coherent receiver employing photonic aided bandpass sampling technology for phase-modulated radio-over-fiber (RoF) links. An optical intensity modulator (IM) is utilized as the bandpass sampler which performs encoded on-off keyed pulse sequence on the optical local oscillator. Quaternary Phase Shift Keying (QPSK) modulated data signal with 20 MHz bandwidth at 5.2 GHz, 10.2 GHz and 15.2 GHz RF carrier frequency is experimentally demonstrated to be successfully detected by using balanced photodiodes (BPDs) with only 800 MHz analog bandwidth. It demonstrates that the required analog bandwidth of BPDs and ADCs can be dramatically reduced in a direct sampled coherent RoF communications system.

  4. An ultrawide-bandwidth single-sideband modulator for terahertz frequencies

    Science.gov (United States)

    Meijer, A. S.; Berden, G.; Arslanov, D. D.; Ozerov, M.; Jongma, R. T.; van der Zande, W. J.

    2016-11-01

    Wireless high-speed data communication using terahertz (THz) carrier frequencies is becoming reality with data rates beyond 100 Gbit s-1. Many of the mobile applications use internet access and require that THz wireless base stations are connected to a global network, such as the radio-over-fibre network. We present the realization of an ultrawide bandwidth THz optical single-sideband (OSSB) modulator for converting (free-space) THz signals to THz optical modulations with an increased spectral efficiency. THz OSSB will mitigate chromatic dispersion-induced propagation losses in optical fibres and support digital modulation schemes. We demonstrate THz OSSB for free-space radiation between 0.3 and 1.0 THz using a specially designed dichroic beamsplitter for signal and carrier, and a planar light-wave circuit with multimode interference structures. This arrangement of optical elements mimics the Hartley single-sideband modulator for electronics signals and accomplishes the required Hilbert transform without any frequency-dependent tuning element over an ultrawide THz spectrum.

  5. Antisocial behaviour and psychopathy: uncovering the externalizing link in the P3 modulation.

    Science.gov (United States)

    Pasion, Rita; Fernandes, Carina; Pereira, Mariana R; Barbosa, Fernando

    2017-03-22

    In 2009, Gao and Raine's meta-analysis analysed P3 modulation over the antisocial spectrum. However, some questions remained open regarding the P3 modulation patterns across impulsive and violent manifestations of antisocial behaviour, phenotypic components of psychopathy, and P3 components. A systematic review of 36 studies was conducted (N=3514) to extend previous results and to address these unresolved questions. A clear link between decreased P3 amplitude and antisocial behaviour was found. In psychopathy, dimensional approaches become more informative than taxonomic models. Distinct etiological pathways of psychopathy were evidenced in cognitive tasks: impulsive-antisocial psychopathic traits mainly predicted blunted P3 amplitude, while interpersonal-affective psychopathic traits explained enhanced P3 amplitude. Supporting the low fear hypothesis, the interpersonal-affective traits were associated with reduced P3 amplitude in emotional-affective learning tasks. From the accumulated knowledge we propose a framework of P3 amplitude modulation that uncovers the externalizing link between psychopathy and antisocial behaviour. However, the main hypotheses are exploratory and call for more data before stablishing robust conclusions.

  6. Inter-island optical link demonstration using high-data-rate pulse-position modulation

    Science.gov (United States)

    Bacher, Michael; Arnold, Felix; Thieme, Björn

    2014-03-01

    The growing data-rate demand on satellite communication systems has led to the increased interest in optical space communication solutions for uplinks and downlinks between satellites and ground stations. As one example for applications that benefit from higher data-rates offered by optical links, RUAG Space studied an uplink scenario from an Unmanned Aerial Vehicle (UAV) to a Geostationary Orbit (GEO), under the European Space Agency project formally known as "Optical Communications Transceiver for Atmospheric Links" (OCTAL). Particularly suitable for optical links through turbulent atmospheres are robust Pulse Position Modulation (PPM) schemes. Communication electronics using a Multi-Pulse PPM (MPPM) scheme have been developed, increasing the data-rate compared to traditional PPM at a constant peak-to-average ratio while allowing a widely configurable data-rate range. The communication system was tested together with a newly developed receiver and transmitter at a wavelength of 1055nm in a field test campaign on the Canary Islands, where the transmitter telescope was located on La Palma while the receiver was installed within the ESA Optical Ground Station on Tenerife. The nearly horizontal link between the two islands with a link distance of 142km allowed validation of relevant system performances under stringent atmospheric conditions. A data-rate of more than 360Mbps could be demonstrated using MPPM, while nearly 220Mbps could be achieved with traditional PPM, well exceeding the targeted data-rate of the studied UAV-to-GEO scenario. Following an introduction on the applied MPPM schemes, the architecture of the test setup is described, different modulation schemes are compared and the test results of this Inter-Island Test Campaign performed in October 2012 are presented.

  7. Performance comparison of two analog photonic links employing a pair of directly modulated lasers and a balanced photodetector

    NARCIS (Netherlands)

    Marpaung, David; Roeloffzen, Chris; Etten, van Wim

    2009-01-01

    We compare the effects of low biasing and push-pull modulation on the spurious-free dynamic range (SFDR) of an analog photonic link (APL) architecture employing a pair of directlymodulated laser diodes and a balanced photodetector.

  8. Low-power multi-chip module and board-level links for data transfer

    Energy Technology Data Exchange (ETDEWEB)

    Carson, R.F.; Hardin, T.L.; Warren, M.E.; Lear, K.L.; Lovejoy, M.L.; Seigal, P.K.; Craft, D.C. [Sandia National Labs., Albuquerque, NM (United States); Enquist, P.J. [Research Triangle Inst., Research Triangle Park, NC (United States)

    1997-03-01

    Advanced device technologies such as Vertical Cavity Surface-Emitting Lasers (VCSELs) and diffractive micro lenses can be obtained with novel packaging techniques to allow low-power interconnection of parallel optical signals. These interconnections can be realized directly on circuit boards, in a multi-chip module format, or in packages that emulate electrical connectors. For applications such as stacking of Multi-Chip Module (MCM) layers, the links may be realized in bi-directional form using integrated diffractive microlenses. In the stacked MCM design, consumed electrical power is minimized by use of a relatively high laser output from high efficiency VCSELs, and a receiver design that is optimized for low power, at the expense of dynamic range. Within certain constraints, the design may be extended to other forms such as board-level interconnects.

  9. Relationship between cross-linking conditions of ethylene vinyl acetate and potential induced degradation for crystalline silicon photovoltaic modules

    Science.gov (United States)

    Jonai, Sachiko; Hara, Kohjiro; Tsutsui, Yuji; Nakahama, Hidenari; Masuda, Atsushi

    2015-08-01

    In this study, we investigated the relationship in crystalline silicon (c-Si) photovoltaic (PV) modules between the cross-linking level of copolymer of ethylene and vinyl acetate (EVA) as the encapsulant and the degree of degradation due to potential induced degradation (PID) phenomenon. We used three methods for the determination of cross-linking level of EVA: xylene method, which is one of the solvent extraction methods (SEM), curing degree by differential scanning calorimetry (DSC), and viscoelastic properties by dynamic mechanical analysis (DMA). The results indicate that degradation of PV modules by PID test depends on the cross-linking level of EVA. The PV modules encapsulated by EVA with higher cross-linking level show lower degradation degree due to PID phenomenon. Also we showed that EVA with higher cross-linking level tended to be higher volume resistivity. This tendency is similar to that for electrical resistance value during the PID test. The PID test was also done by changing thickness of EVA between front cover glass and c-Si with the same cross-linking level. The PV modules encapsulated by thicker EVA between front cover glass and c-Si cell show lower degradation by PID. From these results, the PV modules encapsulated by EVA with higher cross-linking level, higher volume resistivity and increased thickness would be tolerant of PID phenomenon.

  10. Simulink models for performance analysis of high speed DQPSK modulated optical link

    Science.gov (United States)

    Sharan, Lucky; Rupanshi, Chaubey, V. K.

    2016-03-01

    This paper attempts to present the design approach for development of simulation models to study and analyze the transmission of 10 Gbps DQPSK signal over a single channel Peer to Peer link using Matlab Simulink. The simulation model considers the different optical components used in link design with their behavior represented initially by theoretical interpretation, including the transmitter topology, Mach Zehnder Modulator(MZM) module and, the propagation model for optical fibers etc. thus allowing scope for direct realization in experimental configurations. It provides the flexibility to incorporate the various photonic components as either user-defined or fixed and, can also be enhanced or removed from the model as per the design requirements. We describe the detailed operation and need of every component model and its representation in Simulink blocksets. Moreover the developed model can be extended in future to support Dense Wavelength Division Multiplexing (DWDM) system, thereby allowing high speed transmission with N × 40 Gbps systems. The various compensation techniques and their influence on system performance can be easily investigated by using such models.

  11. Simulink models for performance analysis of high speed DQPSK modulated optical link

    Energy Technology Data Exchange (ETDEWEB)

    Sharan, Lucky, E-mail: luckysharan@pilani.bits-pilani.ac.in; Rupanshi,, E-mail: f2011222@pilani.bits-pilani.ac.in; Chaubey, V. K., E-mail: vkc@pilani.bits-pilani.ac.in [EEE Department, BITS-Pilani, Rajasthan, 333031 (India)

    2016-03-09

    This paper attempts to present the design approach for development of simulation models to study and analyze the transmission of 10 Gbps DQPSK signal over a single channel Peer to Peer link using Matlab Simulink. The simulation model considers the different optical components used in link design with their behavior represented initially by theoretical interpretation, including the transmitter topology, Mach Zehnder Modulator(MZM) module and, the propagation model for optical fibers etc. thus allowing scope for direct realization in experimental configurations. It provides the flexibility to incorporate the various photonic components as either user-defined or fixed and, can also be enhanced or removed from the model as per the design requirements. We describe the detailed operation and need of every component model and its representation in Simulink blocksets. Moreover the developed model can be extended in future to support Dense Wavelength Division Multiplexing (DWDM) system, thereby allowing high speed transmission with N × 40 Gbps systems. The various compensation techniques and their influence on system performance can be easily investigated by using such models.

  12. Glucosamine Modulates T Cell Differentiation through Down-regulating N-Linked Glycosylation of CD25.

    Science.gov (United States)

    Chien, Ming-Wei; Lin, Ming-Hong; Huang, Shing-Hwa; Fu, Shin-Huei; Hsu, Chao-Yuan; Yen, B Lin-Ju; Chen, Jiann-Torng; Chang, Deh-Ming; Sytwu, Huey-Kang

    2015-12-04

    Glucosamine has immunomodulatory effects on autoimmune diseases. However, the mechanism(s) through which glucosamine modulates different T cell subsets and diseases remain unclear. We demonstrate that glucosamine impedes Th1, Th2, and iTreg but promotes Th17 differentiation through down-regulating N-linked glycosylation of CD25 and subsequently inhibiting its downstream Stat5 signaling in a dose-dependent manner. The effect of glucosamine on T helper cell differentiation was similar to that induced by anti-IL-2 treatment, further supporting an IL-2 signaling-dependent modulation. Interestingly, excess glucose rescued this glucosamine-mediated regulation, suggesting a functional competition between glucose and glucosamine. High-dose glucosamine significantly decreased Glut1 N-glycosylation in Th1-polarized cells. This finding suggests that both down-regulated IL-2 signaling and Glut1-dependent glycolytic metabolism contribute to the inhibition of Th1 differentiation by glucosamine. Finally, glucosamine treatment inhibited Th1 cells in vivo, prolonged the survival of islet grafts in diabetic recipients, and exacerbated the severity of EAE. Taken together, our results indicate that glucosamine interferes with N-glycosylation of CD25, and thereby attenuates IL-2 downstream signaling. These effects suggest that glucosamine may be an important modulator of T cell differentiation and immune homeostasis.

  13. THz photonic wireless links with 16-QAM modulation in the 375-450 GHz band.

    Science.gov (United States)

    Jia, Shi; Yu, Xianbin; Hu, Hao; Yu, Jinlong; Guan, Pengyu; Da Ros, Francesco; Galili, Michael; Morioka, Toshio; Oxenløwe, Leif K

    2016-10-17

    We propose and experimentally demonstrate THz photonic wireless communication systems with 16-QAM modulation in the 375-450 GHz band. The overall throughput reaches as high as 80 Gbit/s by exploiting four THz channels with 5 Gbaud 16-QAM baseband modulation per channel. We create a coherent optical frequency comb (OFC) for photonic generation of multiple THz carriers based on photo-mixing in a uni-travelling carrier photodiode (UTC-PD). The OFC configuration also allows us to generate reconfigurable THz carriers with low phase noise. The multiple-channel THz radiation is received by using a Schottky mixer based electrical receiver after 0.5 m free-space wireless propagation. 2-channel (40 Gbit/s) and 4-channel (80 Gbit/s) THz photonic wireless links with 16-QAM modulation are reported in this paper, and the bit error rate (BER) performance for all channels in both cases is below the hard decision forward error correction (HD-FEC) threshold of 3.8e-3 with 7% overhead. In addition, we also successfully demonstrate hybrid photonic wireless transmission of 40 Gbit/s 16-QAM signal at carrier frequencies of 400 GHz and 425 GHz over 30 km standard single mode fiber (SSMF) between the optical baseband signal transmitter and the THz wireless transmitter with negligible induced power penalty.

  14. Two-user opportunistic scheduling using hierarchical modulations in wireless networks with heterogenous average link gains

    KAUST Repository

    Hossain, Md Jahangir

    2010-03-01

    Our contribution, in this paper, is two-fold. First, we analyze the performance of a hierarchical modulation-assisted two-best user opportunistic scheduling (TBS) scheme, which was proposed by the authors, in a fading environment where different users have different average link gains. Specifically, we present a new expression for the spectral efficiency (SE) of the users and using this expression, we compare the degrees of fairness (DOF) of the TBS scheme with that of classical single user opportunistic scheduling schemes, namely, absolute carrier-to-noise ratio (CNR) based single-best user scheduling (SBS) and normalized CNR based proportional fair scheduling (PFS) schemes. The second contribution is that we propose a new hybrid two-user opportunistic scheduling (HTS) scheme based on our earlier proposed TBS scheme. This HTS scheme selects the first user based on the largest absolute CNR value among all the users while the second user is selected based on the ratios of the absolute CNRs to the corresponding average CNRs of the remaining users. The total transmission rate i.e., the constellation size is selected according to the absolute CNR of the first best user. The total transmission rate is then allocated among these selected users by joint consideration of their absolute CNRs and allocated number of information bit(s) are transmitted to them using hierarchical modulations. Numerical results are presented for a fading environment where different users experience independent but non-identical (i.n.d.) channel fading. These selected numerical results show that the proposed HTS scheme can considerably increase the system\\'s fairness without any degradation of the link spectral efficiency (LSE) i.e., the multiuser diversity gain compared to the classical SBS scheme. These results also show that the proposed HTS scheme has a lower fairness in comparison to the PFS scheme which suffers from a considerable degradation in LSE. © 2010 IEEE.

  15. Broadband receiver-based distortion elimination in phase-modulated analog optical links using four-wave mixing

    Science.gov (United States)

    Bhatia, Amit; Ting, Hong-Fu; Foster, Mark A.

    2015-03-01

    We present a method for full distortion elimination in phase-modulated analog optical links using the nonlinear optical process of four-wave mixing (FWM). Phase-modulated links consist of a laser and phase modulator in the transmitter and an interferometer (or local oscillator) and photodiode in the receiver. Phase modulation is a linear process, so distortion is introduced in the interferometric detection process. Quadrature biasing eliminates even-order distortion products, leaving only odd-order distortion. Here we introduce a method for eliminating these odd-order distortion products in the receiver. A small portion of the phase-modulated signal is tapped and combined with an unmodulated CW laser to seed a cascaded FWM comb source. This process generates an array of lightwaves with integer multiples of the signal's phase modulation. By suitably scaling and combining these lightwaves with the original signal the overall transfer function of the interferometric receiver can be linearized (or given another tailored shape) through a Fourier synthesis approach. By combining a single lightwave from the generated comb with the original signal, we demonstrate the complete elimination of third-order distortion from the phase-modulated link leaving fifth-order distortion as the dominate source of distortion. We show a 17.6-dB SFDR improvement (1-Hz bandwidth) for a 6 GHz link operating at 5-mA total photocurrent and a 16.4-dB SFDR improvement (1-Hz bandwidth) for a 15 GHz link operating at 10-mA total photocurrent. By appropriately combining additional lightwaves from the generated comb, higher-order distortion products can be eliminated to produce an ideal linear (or custom shaped) transfer function.

  16. Modulation and modeling of monoclonal antibody N-linked glycosylation in mammalian cell perfusion reactors.

    Science.gov (United States)

    Karst, Daniel J; Scibona, Ernesto; Serra, Elisa; Bielser, Jean-Marc; Souquet, Jonathan; Stettler, Matthieu; Broly, Hervé; Soos, Miroslav; Morbidelli, Massimo; Villiger, Thomas K

    2017-09-01

    Mammalian cell perfusion cultures are gaining renewed interest as an alternative to traditional fed-batch processes for the production of therapeutic proteins, such as monoclonal antibodies (mAb). The steady state operation at high viable cell density allows the continuous delivery of antibody product with increased space-time yield and reduced in-process variability of critical product quality attributes (CQA). In particular, the production of a confined mAb N-linked glycosylation pattern has the potential to increase therapeutic efficacy and bioactivity. In this study, we show that accurate control of flow rates, media composition and cell density of a Chinese hamster ovary (CHO) cell perfusion bioreactor allowed the production of a constant glycosylation profile for over 20 days. Steady state was reached after an initial transition phase of 6 days required for the stabilization of extra- and intracellular processes. The possibility to modulate the glycosylation profile was further investigated in a Design of Experiment (DoE), at different viable cell density and media supplement concentrations. This strategy was implemented in a sequential screening approach, where various steady states were achieved sequentially during one culture. It was found that, whereas high ammonia levels reached at high viable cell densities (VCD) values inhibited the processing to complex glycan structures, the supplementation of either galactose, or manganese as well as their synergy significantly increased the proportion of complex forms. The obtained experimental data set was used to compare the reliability of a statistical response surface model (RSM) to a mechanistic model of N-linked glycosylation. The latter outperformed the response surface predictions with respect to its capability and reliability in predicting the system behavior (i.e., glycosylation pattern) outside the experimental space covered by the DoE design used for the model parameter estimation. Therefore, we can

  17. A Brief Investigation of Adaptive Decision Feedback Equalization for Digital HF Links Employing PSK (Phase Shift Keying) Modulation.

    Science.gov (United States)

    2014-09-26

    INVESTIGATION OF ADAPTIVE DECISION FEEDBACK EQUALIZATION FOR DIGITAL HF LINKS EMPLOYING PSKK MODULATION B.E. Sawyer Mission Research Corporation P.O. Drawer 719...IF THE ADDRESSEE IS NO LONGER EMPLOYED BY YOUR ORGANIZATION. 4.’I 4,D % ,=..- ..: O4.’ UNCLASSIFIED SECURITY CLASSIFICATION OF THIS PAGE (When Data...Rot FEEDBACK EQUAL Z FOR IGITAL HF LINKS TcnclRpr PERFORMING ORG. REPORT NUMBERMRC-R-801- 7, AUTHORf,, 8. CONTRACT OR GRANT NUMBER(-) Blair E

  18. Reconfigurable digital receiver for 8PSK subcarrier multiplexed and 16QAM single carrier phase‐modulated radio over fiber links

    DEFF Research Database (Denmark)

    Guerrero Gonzalez, Neil; Zibar, Darko; Yu, Xianbin

    2011-01-01

    A reconfigurable digital receiver based on the k‐means algorithm is proposed for phase‐modulated subcarrier multiplexed (SCM) and quadrature amplitude‐modulated single carrier, phase‐modulated radio‐over‐fiber links. We report successful demodulation after 40 km single mode fiber transmission...... with three 50 Mbaud 8PSK SCM signals and a 312.5 Mbaud 16QAM single carrier. © 2011 Wiley Periodicals, Inc. Microwave Opt Technol Lett 53:1015–1018, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.25905...

  19. CWDM based HDMI interconnect incorporating passively aligned POF linked optical subassembly modules

    Science.gov (United States)

    Lee, Hak-Soon; Lee, Sang-Shin; Son, Yung-Sung

    2011-08-01

    A four-channel transmitter OSA (TOSA) and a receiver optical sub-assembly (ROSA) module were presented. They take advantage of a coarse WDM (CWDM) scheme, employing two types of VCSELs at 780 and 850 nm, where no wavelength filters are involved in the TOSA. The ROSA and TOSA were constructed through a fully passive alignment process using components produced by virtue of a cost effective plastic injection molding technique. In order to build a high quality optical HDMI interconnect, four channel optical links between these modules ware established via two graded-index plastic optical fibers (GI-POFs). The HDMI interconnect was thoroughly evaluated in terms of the alignment tolerance, the light beam propagation, and the data transmission capability. For the ROSA, the measured tolerance, as affected by the photodiode alignment, was ~45 μm and over 200 μm for the transverse and longitudinal directions, respectively. For the TOSA, the tolerance, which is mostly dependent upon the VCSEL alignment, was ~20 μm and more than 200 μm for the transverse and longitudinal directions, respectively. The beam profiles for the TOSA and ROSA were monitored to confirm their feasibility from the optical coupling perspective. A digital signal at 2.5 Gb/s was efficiently transmitted through the HDMI interconnect with a bit error ratio of below 10-16. A 1080p HDMI signal from a Blu-ray player was delivered through the interconnect to an LCD monitor and successfully displayed a high quality video.

  20. The Role of the NASA Global Hawk Link Module as an Information Nexus For Atmospheric Mapping Missions

    Science.gov (United States)

    Sullivan, D. V.

    2015-01-01

    The Link Module described in this paper was developed for the NASA Uninhabited Aerial System (UAS) Global Hawk Pacific Mission (GloPAC) Airborne Science Campaign; four flights of 30 hour duration, supporting the Aura Validation Experiment (AVE). It was used again during the Genesis and Rapid Intensification Processes (GRIP) experiment, a NASA Earth Science field experiment to better understand how tropical storms form and develop into major hurricanes. In these missions, the Link Module negotiated all communication over the high bandwidth Ku satellite link, archived all the science data from onboard experiments in a spatially enabled database, routed command and control of the instruments from the Global Hawk Operations Center, and re-transmitted select data sets directly to experimenters control and analysis systems. The availability of aggregated information from collections of sensors, and remote control capabilities, in real-time, is revolutionizing the way Airborne Science is being conducted. The Link Module NG now being flown in support of the NASA Earth Venture missions, the Hurricane and Severe Storm Sentinel (HS3) mission, and Airborne Tropical Tropopause Experiment (A TTREX) mission, has advanced data fusion technologies that are further advancing the Scientific productivity, flexibility and robustness of these systems. On-the-fly traffic shaping has been developed to allow the high definition video, used for critical flight control segments, to dynamically allocate variable bandwidth on demand. Historically, the Link Module evolved from the instrument and communication interface controller used by NASA's Pathfinder and Pathfinder plus solar powered UAS's in the late 1990' s. It later was expanded for use in the AIRDAS four channel scanner flown on the NASA Altus UAS, and then again to a module in the AMS twelve channel multispectral scanner flying on the NASA (Predator-b) Ikhana UAS. The current system is the answer to the challenges imposed by extremely

  1. The Link between Microbial Diversity and Nitrogen Cycling in Marine Sediments Is Modulated by Macrofaunal Bioturbation.

    Directory of Open Access Journals (Sweden)

    Maryam Yazdani Foshtomi

    Full Text Available The marine benthic nitrogen cycle is affected by both the presence and activity of macrofauna and the diversity of N-cycling microbes. However, integrated research simultaneously investigating macrofauna, microbes and N-cycling is lacking. We investigated spatio-temporal patterns in microbial community composition and diversity, macrofaunal abundance and their sediment reworking activity, and N-cycling in seven subtidal stations in the Southern North Sea.Our results indicated that bacteria (total and β-AOB showed more spatio-temporal variation than archaea (total and AOA as sedimentation of organic matter and the subsequent changes in the environment had a stronger impact on their community composition and diversity indices in our study area. However, spatio-temporal patterns of total bacterial and β-AOB communities were different and related to the availability of ammonium for the autotrophic β-AOB. Highest bacterial richness and diversity were observed in June at the timing of the phytoplankton bloom deposition, while richness of β-AOB as well as AOA peaked in September. Total archaeal community showed no temporal variation in diversity indices.Distance based linear models revealed that, independent from the effect of grain size and the quality and quantity of sediment organic matter, nitrification and N-mineralization were affected by respectively the diversity of metabolically active β-AOB and AOA, and the total bacteria, near the sediment-water interface. Separate models demonstrated a significant and independent effect of macrofaunal activities on community composition and richness of total bacteria, and diversity indices of metabolically active AOA. Diversity of β-AOB was significantly affected by macrofaunal abundance. Our results support the link between microbial biodiversity and ecosystem functioning in marine sediments, and provided broad correlative support for the hypothesis that this relationship is modulated by macrofaunal

  2. Proteasome Modulator 9 SNPs are linked to hypertension in type 2 diabetes families

    Directory of Open Access Journals (Sweden)

    Gragnoli Claudia

    2011-08-01

    Full Text Available Abstract Background Chromosome 12q24 was recently associated with hypertension. Proteasome Modulator 9 (PSMD9 lies in the 12q24 locus and is in linkage with MODY3, type 2 diabetes (T2D, microvascular and macrovascular pathology, carpal tunnel syndrome, and hypercholesterolemia in Italian families. Aims Our goal was to determine whether PSMD9 is linked to elevated blood pressure/hypertension in T2D families. Methods We characterized the Italian T2D families' members for presence and/or absence of elevated blood pressure (≥ 130/80 and/or hypertension. The phenotypes were described as unknown in all cases in which the diagnosis was either unclear or the data were not available for the subject studied. We tested in the 200 Italians families for the presence of the linkage of the PSMD9 T2D risk single nucleotide polymorphisms (SNPs IVS3+nt460 A > G, IVS3+nt437 T > C and E197G A > G with elevated blood pressure/hypertension. The non-parametric linkage analysis was performed for this qualitative phenotype by using the Merlin software; the Lod score and correspondent P-value were calculated. Parametric linkage analysis was also performed. For the significant linkage score, 1000 replicates were run to calculate the empirical P-value. Results The PSMD9 gene SNPs studied are in linkage with elevated blood pressure/hypertension in our Italian families. Conclusions We conclude that the PSMD9 gene and/or any variant in linkage disequilibrium with the SNPs studied contribute to the linkage to hypertension within our family dataset. This is the first report of PSMD9 linkage to hypertension within the 12q24 locus.

  3. Noise figure of microwave photonic links operating under large-signal modulation and its application to optoelectronic oscillators.

    Science.gov (United States)

    Hosseini, Seyyed Esmail; Banai, Ali

    2014-10-01

    The noise performance of intensity-modulation direct-detection microwave photonic links (MWPL) operating under large-signal conditions has been studied in this paper. A sinusoidal signal plus narrowband white Gaussian noise is applied at the radio frequency input of the link, and the output spectrum is derived using a nonlinear analytical approach. We show that the output SNR can be severely affected by the interaction of signal and noise due to the nonlinearity of the MWPL combined with the large input modulating signal. It is shown that the large-signal noise figure (NF) of an MWPL depends on the input power, a dependence that is not readily apparent under small-signal conditions, due to two unavoidable issues appearing in the large-signal conditions: (1) the link power gain is a function of its input power, and (2) the link power gain is not the same for the signal and noise due to the capture effect. We also have observed that if shot noise or laser relative intensity noise (RIN) is the dominant source of noise, link large-signal NF increases as the input signal power increases. We have shown that, when the MWPL is operating in the linear regime, our theoretical predictions approach the already published results on small-signal NF, which are verified by experimental data. We have shown that large-signal NF affects the noise performance of optoelectronic oscillators because they contain MWPLs at saturation.

  4. Analysis of voltage modulation based active damping techniques for small DC-link drive system

    DEFF Research Database (Denmark)

    Wang, Dong; Lu, Kaiyuan; Rasmussen, Peter Omand;

    2015-01-01

    Small DC-link drive system, built with film capacitor in the DC link, may have the advantages of longer lifetime and the possibility to achieve a more compact design of capacitor bank at medium and high power rates. However, it exhibits instability problem, especially when it is fed by a soft grid...

  5. Smooth muscle cell phenotype modulation and contraction on native and cross-linked polyelectrolyte multilayers.

    Science.gov (United States)

    Moussallem, Maroun D; Olenych, Scott G; Scott, Shannon L; Keller, Thomas C S; Schlenoff, Joseph B

    2009-11-09

    Smooth muscle cells convert between a motile, proliferative "synthetic" phenotype and a sessile, "contractile" phenotype. The ability to manipulate the phenotype of aortic smooth muscle cells with thin biocompatible polyelectrolyte multilayers (PEMUs) with common surface chemical characteristics but varying stiffness was investigated. The stiffness of (PAH/PAA) PEMUs was varied by heating to form covalent amide bond cross-links between the layers. Atomic force microscopy (AFM) showed that cross-linked PEMUs were thinner than those that were not cross-linked. AFM nanoindentation demonstrated that the Young's modulus ranged from 6 MPa for hydrated native PEMUs to more than 8 GPa for maximally cross-linked PEMUs. Rat aortic A7r5 smooth muscle cells cultured on native PEMUs exhibited morphology and motility of synthetic cells and expression of the synthetic phenotype markers vimentin, tropomyosin 4, and nonmuscle myosin heavy chain IIB (nmMHCIIB). In comparison, cells cultured on maximally cross-linked PEMUs exhibited the phenotype markers calponin, smooth muscle myosin heavy chain (smMHC), myocardin, transgelin, and smooth muscle alpha-actin (smActin) that are characteristic of the smooth muscle "contractile" phenotype. Consistent with those cells being "contractile", A7r5 cells grown on cross-linked PEMUs produced contractile force when stimulated with a Ca(2+) ionophore.

  6. Half-cycle QAM modulation for VCSEL-based optical links

    DEFF Research Database (Denmark)

    Pham, Tien Thang; Rodes Lopez, Roberto; Jensen, Jesper Bevensee;

    2012-01-01

    Abstract (40-Word Limit): Novel spectrally efficient half-cycle QAM modulation is experimentally demonstrated. 10 Gbps 4-QAM signal in 7.5-GHz bandwidth was successfully transmitted over 20 km SMF using an un-cooled 1.5 µm VCSEL with no equalization applied.......Abstract (40-Word Limit): Novel spectrally efficient half-cycle QAM modulation is experimentally demonstrated. 10 Gbps 4-QAM signal in 7.5-GHz bandwidth was successfully transmitted over 20 km SMF using an un-cooled 1.5 µm VCSEL with no equalization applied....

  7. Failure to Modulate Attentional Control in Advanced Aging Linked to White Matter Pathology

    Science.gov (United States)

    Van Dijk, Koene R. A.; Shire, Emily H.; Sperling, Reisa A.; Johnson, Keith A.; Buckner, Randy L.

    2012-01-01

    Advanced aging is associated with reduced attentional control and less flexible information processing. Here, the origins of these cognitive effects were explored using a functional magnetic resonance imaging task that systematically varied demands to shift attention and inhibit irrelevant information across task blocks. Prefrontal and parietal regions previously implicated in attentional control were recruited by the task and most so for the most demanding task configurations. A subset of older individuals did not modulate activity in frontal and parietal regions in response to changing task requirements. Older adults who did not dynamically modulate activity underperformed their peers and scored more poorly on neuropsychological measures of executive function and speed of processing. Examining 2 markers of preclinical pathology in older adults revealed that white matter hyperintensities (WMHs), but not high amyloid burden, were associated with failure to modulate activity in response to changing task demands. In contrast, high amyloid burden was associated with alterations in default network activity. These results suggest failure to modulate frontal and parietal activity reflects a disruptive process in advanced aging associated with specific neuropathologic processes. PMID:21765181

  8. Oxytocin modulates the link between adult attachment and cooperation through reduced betrayal aversion

    NARCIS (Netherlands)

    de Dreu, C.K.W.

    2012-01-01

    An experiment examined whether and how the relationship between individual differences in social attachment and cooperation is modulated by brain oxytocin, a neuropeptide implicated both in parent-child bonding, and in social approach. Healthy males completed a validated attachment style measure, re

  9. 71-Mbit/s ultraviolet-B LED communication link based on 8-QAM-OFDM modulation

    KAUST Repository

    Sun, Xiaobin

    2017-09-14

    A demonstration of ultraviolet-B (UVB) communication link is implemented utilizing quadrature amplitude modulation (QAM) orthogonal frequency-division multiplexing (OFDM). The demonstration is based on a 294-nm UVB-light-emitting-diode (UVB-LED) with a full-width at half-maximum (FWHM) of 9 nm and light output power of 190 μW, at 7 V, with a special silica gel lens on top of it. A −3-dB bandwidth of 29 MHz was measured and a high-speed near-solar-blind communication link with a data rate of 71 Mbit/s was achieved using 8-QAM-OFDM at perfect alignment. 23.6 Mbit/s using 2-QAM-OFDM when the angle subtended by the pointing directions of the UVB-LED and photodetector (PD) is 12 degrees, thus establishing a diffuse-line-of-sight (LOS) link. The measured bit-error rate (BER) of 2.8 × 10−4 and 2.4 × 10−4, respectively, are well below the forward error correction (FEC) criterion of 3.8 × 10−3. The demonstrated high data-rate OFDM-based UVB communication link paves the way for realizing high-speed non-line-of-sight free-space optical communications.

  10. Multiband Carrierless Amplitude Phase Modulation for High Capacity Optical Data Links

    DEFF Research Database (Denmark)

    Iglesias Olmedo, Miguel; Zuo, Tianjian; Jensen, Jesper Bevensee;

    2014-01-01

    Short range optical data links are experiencing bandwidth limitations making it very challenging to cope with the growing data transmission capacity demands. Parallel optics appears as a valid short-term solution. It is, however, not a viable solution in the long-term because of its complex optic...

  11. Oxytocin modulates the link between adult attachment and cooperation through reduced betrayal aversion.

    Science.gov (United States)

    De Dreu, Carsten K W

    2012-07-01

    An experiment examined whether and how the relationship between individual differences in social attachment and cooperation is modulated by brain oxytocin, a neuropeptide implicated both in parent-child bonding, and in social approach. Healthy males completed a validated attachment style measure, received intranasal oxytocin or placebo, and privately chose between cooperation and non-cooperation in an incentivized social dilemma with an anonymous stranger. Attachment anxiety--the tendency to fear rejection by others--had few effects and was not modulated by oxytocin. However, oxytocin interacted with attachment avoidance--the tendency to fear dependency and closeness in interpersonal relations. Especially among participants high rather than low in attachment avoidance, oxytocin reduced betrayal aversion, and increased trust and cooperation compared to placebo. Effects of attachment avoidance and oxytocin on cooperation were mediated by betrayal aversion, and not by affiliation tendencies.

  12. Investigations of Polarization Dependent Loss in Polarization Modulated Analog Optical Links

    Science.gov (United States)

    2015-12-29

    to minimize the 2nd harmonic at -16 dBm input RF power after adding PDL (Black). 10      Fig. 4.2: Curves for 4.1 V bias applied after PDL...Directorate for Information Operations and Reports (0704-0188), 1215 Jefferson Davis Highway, Suite 1204, Arlington, VA 22202-4302. Respondents should be...nonlinearity. Finally, the polarization modulator nonlinearities are investigated, with the results showing the tradeoffs for using either the DC bias of a

  13. Microwave photonic frequency down-conversion link based on intensity and phase paralleled modulation

    Science.gov (United States)

    Li, Jingnan; Wang, Yunxin; Wang, Dayong; Du, Haozheng; Zhou, Tao; Zhong, Xin; Yang, Dengcai; Li, Hongli

    2016-01-01

    A photonic microwave down-conversion approach is proposed and experimentally demonstrated based on a Mach-Zehnder modulator paralleled with a phase modulator. The incident radio frequency signal and the local oscillator signal are feed to the MZM and PM, respectively, and these two modulated optical signals interfere in the coupler. The useless higher-order sidebands are removed by a tunable optical band-pass filter. The principle of microwave frequency down-conversion is analyzed theoretically, the MZM and PM paralleled frequency down-conversion system is built. Then the performance of system is tested, and the experimental results show that the spurious-free dynamic range achieves 104.8 dB:Hz2/3. Compared to the conventional MZM-MZM cascaded system, the SFDR has been improved by 16 dB. The MZM and PM paralleled frequency down-conversion system can balance the intensity of the two coherent beams easily, and only single DC bias is needed. The proposed method possesses simple structure and high dynamic range.

  14. Simultaneous backward data transmission and power harvesting in an ultrasonic transcutaneous energy transfer link employing acoustically dependent electric impedance modulation.

    Science.gov (United States)

    Ozeri, Shaul; Shmilovitz, Doron

    2014-09-01

    The advancement and miniaturization of body implanted medical devices pose several challenges to Ultrasonic Transcutaneous Energy Transfer (UTET), such as the need to reduce the size of the piezoelectric resonator, and the need to maximize the UTET link power-transfer efficiency. Accordingly, the same piezoelectric resonator that is used for energy harvesting at the body implant, may also be used for ultrasonic backward data transfer, for instance, through impedance modulation. This paper presents physical considerations and design guidelines of the body implanted transducer of a UTET link with impedance modulation for a backward data transfer. The acoustic matching design procedure was based on the 2×2 transfer matrix chain analysis, in addition to the Krimholtz Leedom and Matthaei KLM transmission line model. The UTET power transfer was carried out at a frequency of 765 kHz, continuous wave (CW) mode. The backward data transfer was attained by inserting a 9% load resistance variation around its matched value (550 Ohm), resulting in a 12% increase in the acoustic reflection coefficient. A backward data transmission rate of 1200 bits/s was experimentally demonstrated using amplitude shift keying, simultaneously with an acoustic power transfer of 20 mW to the implant.

  15. Performance of the CMS Tracker Optical Links and Future Upgrade Using Bandwidth Efficient Digital Modulation

    CERN Document Server

    Dris, Stefanos; Troska, J

    2006-01-01

    The Compact Muon Solenoid (CMS) experiment at the Large Hadron Collider (LHC) particle accelerator will begin operation in 2007. The innermost CMS subdetector, the Tracker, comprises ~10 million detector channels read out by ~40 000 analog optical links. The optoelectronic components have been designed to meet the stringent requirements of a high energy physics (HEP) experiment in terms of radiation hardness, low mass and low power. Extensive testing has been performed on the components and on complete optical links in test systems. Their functionality and performance in terms of gain, noise, linearity, bandwidth and radiation hardness is detailed. Particular emphasis is placed on the gain, which directly affects the dynamic range of the detector data. It has been possible to accurately predict the variation in gain that will be observed throughout the system. A simulation based on production test data showed that the average gain would be ~38% higher than the design target at the Tracker operating temperatur...

  16. Frequency-Modulated Microwave Photonic Links with Direct Detection: Review and Theory

    Science.gov (United States)

    2010-12-15

    approach for digital signals looks at an eye diagram and uses a Levenberg-Marquart optimization to maximize the eye opening. • LMSE / minimize ISI [56...FFT number o f po in t s etaMHz = param ( 3 ) ; % Frequency modulation e f f i c i e n c y in MHz/mA G = param ( 4 ) ; % RIM norma l i za t ion...in MHz/mA G = param ( 4 ) ; % RIM norma l i za t ion parameter PmW = param ( 5 ) ; % Opt i ca l power b e f o r e the f i l t e r s R = param ( 6

  17. Analysis of Candida albicans mutants defective in the Cdk8 module of mediator reveal links between metabolism and biofilm formation.

    Directory of Open Access Journals (Sweden)

    Allia K Lindsay

    2014-10-01

    Full Text Available Candida albicans biofilm formation is a key virulence trait that involves hyphal growth and adhesin expression. Pyocyanin (PYO, a phenazine secreted by Pseudomonas aeruginosa, inhibits both C. albicans biofilm formation and development of wrinkled colonies. Using a genetic screen, we identified two mutants, ssn3Δ/Δ and ssn8Δ/Δ, which continued to wrinkle in the presence of PYO. Ssn8 is a cyclin-like protein and Ssn3 is similar to cyclin-dependent kinases; both proteins are part of the heterotetrameric Cdk8 module that forms a complex with the transcriptional co-regulator, Mediator. Ssn3 kinase activity was also required for PYO sensitivity as a kinase dead mutant maintained a wrinkled colony morphology in the presence of PYO. Furthermore, similar phenotypes were observed in mutants lacking the other two components of the Cdk8 module-Srb8 and Srb9. Through metabolomics analyses and biochemical assays, we showed that a compromised Cdk8 module led to increases in glucose consumption, glycolysis-related transcripts, oxidative metabolism and ATP levels even in the presence of PYO. In the mutant, inhibition of respiration to levels comparable to the PYO-treated wild type inhibited wrinkled colony development. Several lines of evidence suggest that PYO does not act through Cdk8. Lastly, the ssn3 mutant was a hyperbiofilm former, and maintained higher biofilm formation in the presence of PYO than the wild type. Together these data provide novel insights into the role of the Cdk8 module of Mediator in regulation of C. albicans physiology and the links between respiratory activity and both wrinkled colony and biofilm development.

  18. Peroxisome Proliferator-Activated Receptor Agonists Modulate Neuropathic Pain: a Link to Chemokines?

    Directory of Open Access Journals (Sweden)

    Caroline eFreitag

    2014-08-01

    Full Text Available Chronic pain presents a widespread and intractable medical problem. While numerous pharmaceuticals are used to treat chronic pain, drugs that are safe for extended use and highly effective at treating the most severe pain do not yet exist. Chronic pain resulting from nervous system injury (neuropathic pain is common in conditions ranging from multiple sclerosis to HIV-1 infection to type II diabetes. Inflammation caused by neuropathy is believed to contribute to the generation and maintenance of neuropathic pain. Chemokines are key inflammatory mediators, several of which (MCP-1, RANTES, MIP-1α, fractalkine, SDF-1 among others have been linked to chronic, neuropathic pain in both human conditions and animal models. The important roles chemokines play in inflammation and pain make them an attractive therapeutic target. Peroxisome proliferator-activated receptors are a family of nuclear receptors known for their roles in metabolism. Recent research has revealed that PPARs also play a role in inflammatory gene repression. PPAR agonists have wide-ranging effects including inhibition of chemokine expression and pain behavior reduction in animal models. Experimental evidence suggests a connection between PPAR agonists' pain ameliorating effects and suppression of inflammatory gene expression, including chemokines. In early clinical research, one PPARα agonist, palmitoylethanolamide, shows promise in relieving chronic pain. If this link can be better established, PPAR agonists may represent a new drug therapy for neuropathic pain.

  19. Modulation of epidermal transcription circuits in psoriasis: new links between inflammation and hyperproliferation.

    Directory of Open Access Journals (Sweden)

    William R Swindell

    Full Text Available BACKGROUND: Whole-genome expression profiling has been used to characterize molecular-level differences between psoriasis lesions and normal skin. Pathway analysis, however, is complicated by the fact that expression profiles have been derived from bulk skin biopsies with RNA derived from multiple cell types. RESULTS: We analyzed gene expression across a large sample of psoriatic (PP and uninvolved/normal (PN skin biopsies (n = 215 patients. We identified 1975 differentially expressed genes, including 8 associated with psoriasis susceptibility loci. To facilitate pathway analysis, PP versus PN differences in gene expression were analyzed with respect to 235 gene modules, each containing genes with a similar expression pattern in keratinocytes and epidermis. We identified 30 differentially expressed modules (DEMs biased towards PP-increased or PP-decreased expression. These DEMs were associated with regulatory axes involving cytokines (e.g., IFN-γ, IL-17A, TNF-α, transcription factors (e.g., STAT1, NF-κB, E2F, RUNX1 and chromatin modifiers (SETDB1. We identified an interferon-induced DEM with genes encoding anti-viral proteins (designated "STAT1-57", which was activated in psoriatic epidermis but repressed following biologic therapy. Genes within this DEM shared a motif near the transcription start site resembling the interferon-stimulated response element (ISRE. CONCLUSIONS: We analyzed a large patient cohort and developed a new approach for delineating epidermis-specific pathways and regulatory mechanisms that underlie altered gene expression in psoriasis. Our findings highlight previously unrecognized "transcription circuits" that can provide targets for development of non-systemic therapies.

  20. Solution conformation of C-linked antifreeze glycoprotein analogues and modulation of ice recrystallization.

    Science.gov (United States)

    Tam, Roger Y; Rowley, Christopher N; Petrov, Ivan; Zhang, Tianyi; Afagh, Nicholas A; Woo, Tom K; Ben, Robert N

    2009-11-01

    Antifreeze glycoproteins (AFGPs) are a unique class of proteins that are found in many organisms inhabiting subzero environments and ensure their survival by preventing ice growth in vivo. During the last several years, our laboratory has synthesized functional C-linked AFGP analogues (3 and 5) that possess custom-tailored antifreeze activity suitable for medical, commercial, and industrial applications. These compounds are potent inhibitors of ice recrystallization and do not exhibit thermal hysteresis. The current study explores how changes in the length of the amide-containing side chain between the carbohydrate moiety and the polypeptide backbone in 5 influences ice recrystallization inhibition (IRI) activity. Analogue 5 (n = 3, where n is the number of carbons in the side chain) was a potent inhibitor of ice recrystallization, while 4, 6, and 7 (n = 4, 2, and 1, respectively) exhibited no IRI activity. The solution conformation of the polypeptide backbone in C-linked AFGP analogues 4-7 was examined using circular dichroism (CD) spectroscopy. The results suggested that all of the analogues exhibit a random coil conformation in solution and that the dramatic increase in IRI activity observed with 5 is not due to a change in long-range solution conformation. Variable-temperature (1)H NMR studies on truncated analogues 26-28 failed to elucidate the presence of persistent intramolecular bonds between the amide in the side chain and the peptide backbone. Molecular dynamics simulations performed on these analogues also failed to show persistent intramolecular hydrogen bonds. However, the simulations did indicate that the side chain of IRI-active analogue 26 (n = 3) adopts a unique short-range solution conformation in which it is folded back onto the peptide backbone, orienting the more hydrophilic face of the carbohydrate moiety away from the bulk solvent. In contrast, the solution conformation of IRI-inactive analogues 25, 27, and 28 had fully extended side chains

  1. A system-level model for high-speed, radiation-hard optical links in HEP experiments based on silicon Mach-Zehnder modulators

    Science.gov (United States)

    Zeiler, M.; Detraz, S.; Olantera, L.; Sigaud, C.; Soos, C.; Troska, J.; Vasey, F.

    2016-12-01

    Silicon Mach-Zehnder modulators have been shown to be relatively insensitive to displacement damage beyond a 1-MeV-equivalent neutron fluence of 3ṡ1016n/cm2. Recent investigations on optimized device designs have also led to a high resistance against total ionizing dose levels of above 1 MGy. Such devices could potentially replace electrical and/or optical links close to the particle interaction points in future high energy physics experiments. Since they require an external continuous-wave light source, radiation-hard optical links based on silicon Mach-Zehnder modulators need to have a different system design when compared to existing directly modulated laser-based optical links. 10 Gb/s eye diagrams of irradiated Mach-Zehnder modulators were measured. The outcomes demonstrate the suitability for using these components in harsh radiation environments. A proposal for the implementation of silicon Mach-Zehnder modulators in CERN's particle detectors was developed and a model to calculate the system performance is presented. The optical power budget and the electrical power dissipation of the proposed link is compared to that of the upcoming Versatile Link system that will be installed in 2018.

  2. A dual role for integrin-linked kinase and β1-integrin in modulating cardiac aging.

    Science.gov (United States)

    Nishimura, Mayuko; Kumsta, Caroline; Kaushik, Gaurav; Diop, Soda B; Ding, Yun; Bisharat-Kernizan, Jumana; Catan, Hannah; Cammarato, Anthony; Ross, Robert S; Engler, Adam J; Bodmer, Rolf; Hansen, Malene; Ocorr, Karen

    2014-06-01

    Cardiac performance decreases with age, which is a major risk factor for cardiovascular disease and mortality in the aging human population, but the molecular mechanisms underlying cardiac aging are still poorly understood. Investigating the role of integrin-linked kinase (ilk) and β1-integrin (myospheroid, mys) in Drosophila, which colocalize near cardiomyocyte contacts and Z-bands, we find that reduced ilk or mys function prevents the typical changes of cardiac aging seen in wildtype, such as arrhythmias. In particular, the characteristic increase in cardiac arrhythmias with age is prevented in ilk and mys heterozygous flies with nearly identical genetic background, and they live longer, in line with previous findings in Caenorhabditis elegans for ilk and in Drosophila for mys. Consistent with these findings, we observed elevated β1-integrin protein levels in old compared with young wild-type flies, and cardiac-specific overexpression of mys in young flies causes aging-like heart dysfunction. Moreover, moderate cardiac-specific knockdown of integrin-linked kinase (ILK)/integrin pathway-associated genes also prevented the decline in cardiac performance with age. In contrast, strong cardiac knockdown of ilk or ILK-associated genes can severely compromise cardiac integrity, including cardiomyocyte adhesion and overall heart function. These data suggest that ilk/mys function is necessary for establishing and maintaining normal heart structure and function, and appropriate fine-tuning of this pathway can retard the age-dependent decline in cardiac performance and extend lifespan. Thus, ILK/integrin-associated signaling emerges as an important and conserved genetic mechanism in longevity, and as a new means to improve age-dependent cardiac performance, in addition to its vital role in maintaining cardiac integrity.

  3. N-linked glycans within the A2 domain of von Willebrand factor modulate macrophage-mediated clearance.

    Science.gov (United States)

    Chion, Alain; O'Sullivan, Jamie M; Drakeford, Clive; Bergsson, Gudmundur; Dalton, Niall; Aguila, Sonia; Ward, Soracha; Fallon, Padraic G; Brophy, Teresa M; Preston, Roger J S; Brady, Lauren; Sheils, Orla; Laffan, Michael; McKinnon, Thomas A J; O'Donnell, James S

    2016-10-13

    Enhanced von Willebrand factor (VWF) clearance is important in the etiology of von Willebrand disease. However, the molecular mechanisms underlying VWF clearance remain poorly understood. In this study, we investigated the role of VWF domains and specific glycan moieties in regulating in vivo clearance. Our findings demonstrate that the A1 domain of VWF contains a receptor-recognition site that plays a key role in regulating the interaction of VWF with macrophages. In A1-A2-A3 and full-length VWF, this macrophage-binding site is cryptic but becomes exposed following exposure to shear or ristocetin. Previous studies have demonstrated that the N-linked glycans within the A2 domain play an important role in modulating susceptibility to ADAMTS13 proteolysis. We further demonstrate that these glycans presented at N1515 and N1574 also play a critical role in protecting VWF against macrophage binding and clearance. Indeed, loss of the N-glycan at N1515 resulted in markedly enhanced VWF clearance that was significantly faster than that observed with any previously described VWF mutations. In addition, A1-A2-A3 fragments containing the N1515Q or N1574Q substitutions also demonstrated significantly enhanced clearance. Importantly, clodronate-induced macrophage depletion significantly attenuated the increased clearance observed with N1515Q and N1574Q in both full-length VWF and A1-A2-A3. Finally, we further demonstrate that loss of these N-linked glycans does not enhance clearance in VWF in the presence of a structurally constrained A2 domain. Collectively, these novel findings support the hypothesis that conformation of the VWF A domains plays a critical role in modulating macrophage-mediated clearance of VWF in vivo.

  4. PINCH proteins regulate cardiac contractility by modulating integrin-linked kinase-protein kinase B signaling.

    Science.gov (United States)

    Meder, Benjamin; Huttner, Inken G; Sedaghat-Hamedani, Farbod; Just, Steffen; Dahme, Tillman; Frese, Karen S; Vogel, Britta; Köhler, Doreen; Kloos, Wanda; Rudloff, Jessica; Marquart, Sabine; Katus, Hugo A; Rottbauer, Wolfgang

    2011-08-01

    Integrin-linked kinase (ILK) is an essential component of the cardiac mechanical stretch sensor and is bound in a protein complex with parvin and PINCH proteins, the so-called ILK-PINCH-parvin (IPP) complex. We have recently shown that inactivation of ILK or β-parvin activity leads to heart failure in zebrafish via reduced protein kinase B (PKB/Akt) activation. Here, we show that PINCH proteins localize at sarcomeric Z disks and costameres in the zebrafish heart and skeletal muscle. To investigate the in vivo role of PINCH proteins for IPP complex stability and PKB signaling within the vertebrate heart, we inactivated PINCH1 and PINCH2 in zebrafish. Inactivation of either PINCH isoform independently leads to instability of ILK, loss of stretch-responsive anf and vegf expression, and progressive heart failure. The predominant cause of heart failure in PINCH morphants seems to be loss of PKB activity, since PKB phosphorylation at serine 473 is significantly reduced in PINCH-deficient hearts and overexpression of constitutively active PKB reconstitutes cardiac function in PINCH morphants. These findings highlight the essential function of PINCH proteins in controlling cardiac contractility by granting IPP/PKB-mediated signaling.

  5. Sox4 Links Tumor Suppression to Accelerated Aging in Mice by Modulating Stem Cell Activation

    Directory of Open Access Journals (Sweden)

    Miguel Foronda

    2014-07-01

    Full Text Available Sox4 expression is restricted in mammals to embryonic structures and some adult tissues, such as lymphoid organs, pancreas, intestine, and skin. During embryogenesis, Sox4 regulates mesenchymal and neural progenitor survival, as well as lymphocyte and myeloid differentiation, and contributes to pancreas, bone, and heart development. Aberrant Sox4 expression is linked to malignant transformation and metastasis in several types of cancer. To understand the role of Sox4 in the adult organism, we first generated mice with reduced whole-body Sox4 expression. These mice display accelerated aging and reduced cancer incidence. To specifically address a role for Sox4 in adult stem cells, we conditionally deleted Sox4 (Sox4cKO in stratified epithelia. Sox4cKO mice show increased skin stem cell quiescence and resistance to chemical carcinogenesis concomitantly with downregulation of cell cycle, DNA repair, and activated hair follicle stem cell pathways. Altogether, these findings highlight the importance of Sox4 in regulating adult tissue homeostasis and cancer.

  6. Nonlinearities tolerant modulation format enabled Tb/s superchannel transmission over 420 km of unrepeated Raman amplified link

    Science.gov (United States)

    Bilal, Syed Muhammad; Goroshko, Kseniia; Louchet, Hadrien; Koltchanov, Igor; Richter, André

    2017-07-01

    the same transmission distance and capacity. So for practical realization the nonlinearity robust modulation format PM-QPSK using SRO has been identified as the most promising approach for superchannel implementation of unrepeated Raman amplified links.

  7. Integrin-linked kinase (ILK) modulates wound healing through regulation of hepatocyte growth factor (HGF)

    Energy Technology Data Exchange (ETDEWEB)

    Serrano, Isabel; Diez-Marques, Maria L.; Rodriguez-Puyol, Manuel [Department of Physiology, University of Alcala, Alcala de Henares, Madrid (Spain); Red de Investigacion Renal Cooperativa (RedinRen) (Spain); Instituto Reina Sofia de Investigacion Nefrologica (Spain); Herrero-Fresneda, Inmaculada [Nephrology Unit, IDIBELL, Hospital de Bellvitge, Barcelona (Spain); Red de Investigacion Renal Cooperativa (RedinRen) (Spain); Garcia del Moral, Raimundo [Department of Pathology, University of Granada (Spain); Red de Investigacion Renal Cooperativa (RedinRen) (Spain); Dedhar, Shoukat [Department of Integrative Oncology, BC Cancer Research Center, Vancouver, BC (Canada); Ruiz-Torres, Maria P., E-mail: mpiedad.ruiz@uah.es [Department of Physiology, University of Alcala, Alcala de Henares, Madrid (Spain); Red de Investigacion Renal Cooperativa (RedinRen) (Spain); Instituto Reina Sofia de Investigacion Nefrologica (Spain); Rodriguez-Puyol, Diego [Nephrology Unit, Hospital Universitario Principe de Asturias, Alcala de Henares, Madrid (Spain); Red de Investigacion Renal Cooperativa (RedinRen) (Spain); Instituto Reina Sofia de Investigacion Nefrologica (Spain)

    2012-11-15

    Integrin-linked kinase (ILK) is an intracellular effector of cell-matrix interactions and regulates many cellular processes, including growth, proliferation, survival, differentiation, migration, invasion and angiogenesis. The present work analyzes the role of ILK in wound healing in adult animals using a conditional knock-out of the ILK gene generated with the tamoxifen-inducible Cre-lox system (CRE-LOX mice). Results show that ILK deficiency leads to retarded wound closure in skin. Intracellular mechanisms involved in this process were analyzed in cultured mouse embryonic fibroblast (MEF) isolated from CRE-LOX mice and revealed that wounding promotes rapid activation of phosphatidylinositol 3-kinase (PI3K) and ILK. Knockdown of ILK resulted in a retarded wound closure due to a decrease in cellular proliferation and loss of HGF protein expression during the healing process, in vitro and in vivo. Alterations in cell proliferation and wound closure in ILK-deficient MEF or mice could be rescued by exogenous administration of human HGF. These data demonstrate, for the first time, that the activation of PI3K and ILK after skin wounding are critical for HGF-dependent tissue repair and wound healing. -- Highlights: Black-Right-Pointing-Pointer ILK deletion results in decreased HGF expression and delayed scratch wound repair. Black-Right-Pointing-Pointer PI3K/ILK/AKT pathway signals through HGF to regulate wound healing. Black-Right-Pointing-Pointer An ILK-dependent increase in HGF expression is responsible for wound healing in vivo. Black-Right-Pointing-Pointer ILK-KO mice are used to confirm the requirement for ILK function in wound healing. Black-Right-Pointing-Pointer Human HGF treatment restores delayed wound closure in vitro and in vivo.

  8. Bit-error-rate performance analysis of self-heterodyne detected radio-over-fiber links using phase and intensity modulation

    DEFF Research Database (Denmark)

    Yin, Xiaoli; Yu, Xianbin; Tafur Monroy, Idelfonso

    2010-01-01

    We theoretically and experimentally investigate the performance of two self-heterodyne detected radio-over-fiber (RoF) links employing phase modulation (PM) and quadrature biased intensity modulation (IM), in term of bit-error-rate (BER) and optical signal-to-noise-ratio (OSNR). In both links, self......-heterodyne receivers perform down-conversion of radio frequency (RF) subcarrier signal. A theoretical model including noise analysis is constructed to calculate the Q factor and estimate the BER performance. Furthermore, we experimentally validate our prediction in the theoretical modeling. Both the experimental...

  9. Bit-error-rate performance analysis of self-heterodyne detected radio-over-fiber links using phase and intensity modulation

    DEFF Research Database (Denmark)

    Yin, Xiaoli; Yu, Xianbin; Tafur Monroy, Idelfonso

    2010-01-01

    -heterodyne receivers perform down-conversion of radio frequency (RF) subcarrier signal. A theoretical model including noise analysis is constructed to calculate the Q factor and estimate the BER performance. Furthermore, we experimentally validate our prediction in the theoretical modeling. Both the experimental......We theoretically and experimentally investigate the performance of two self-heterodyne detected radio-over-fiber (RoF) links employing phase modulation (PM) and quadrature biased intensity modulation (IM), in term of bit-error-rate (BER) and optical signal-to-noise-ratio (OSNR). In both links, self...

  10. Recognition of modification status on a histone H3 tail by linked histone reader modules of the epigenetic regulator UHRF1.

    Science.gov (United States)

    Arita, Kyohei; Isogai, Shin; Oda, Takashi; Unoki, Motoko; Sugita, Kazuya; Sekiyama, Naotaka; Kuwata, Keiko; Hamamoto, Ryuji; Tochio, Hidehito; Sato, Mamoru; Ariyoshi, Mariko; Shirakawa, Masahiro

    2012-08-07

    Multiple covalent modifications on a histone tail are often recognized by linked histone reader modules. UHRF1 [ubiquitin-like, containing plant homeodomain (PHD) and really interesting new gene (RING) finger domains 1], an essential factor for maintenance of DNA methylation, contains linked two-histone reader modules, a tandem Tudor domain and a PHD finger, tethered by a 17-aa linker, and has been implicated to link histone modifications and DNA methylation. Here, we present the crystal structure of the linked histone reader modules of UHRF1 in complex with the amino-terminal tail of histone H3. Our structural and biochemical data provide the basis for combinatorial readout of unmodified Arg-2 (H3-R2) and methylated Lys-9 (H3-K9) by the tandem tudor domain and the PHD finger. The structure reveals that the intermodule linker plays an essential role in the formation of a histone H3-binding hole between the reader modules by making extended contacts with the tandem tudor domain. The histone H3 tail fits into the hole by adopting a compact fold harboring a central helix, which allows both of the reader modules to simultaneously recognize the modification states at H3-R2 and H3-K9. Our data also suggest that phosphorylation of a linker residue can modulate the relative position of the reader modules, thereby altering the histone H3-binding mode. This finding implies that the linker region plays a role as a functional switch of UHRF1 involved in multiple regulatory pathways such as maintenance of DNA methylation and transcriptional repression.

  11. A bacterial glycan core linked to surface (S)-layer proteins modulates host immunity through Th17 suppression.

    Science.gov (United States)

    Settem, R P; Honma, K; Nakajima, T; Phansopa, C; Roy, S; Stafford, G P; Sharma, A

    2013-03-01

    Tannerella forsythia is a pathogen implicated in periodontitis, an inflammatory disease of the tooth-supporting tissues often leading to tooth loss. This key periodontal pathogen is decorated with a unique glycan core O-glycosidically linked to the bacterium's proteinaceous surface (S)-layer lattice and other glycoproteins. Herein, we show that the terminal motif of this glycan core acts to modulate dendritic cell effector functions to suppress T-helper (Th)17 responses. In contrast to the wild-type bacterial strain, infection with a mutant strain lacking the complete S-layer glycan core induced robust Th17 and reduced periodontal bone loss in mice. Our findings demonstrate that surface glycosylation of this pathogen may act to ensure its persistence in the host likely through suppression of Th17 responses. In addition, our data suggest that the bacterium then induces the Toll-like receptor 2-Th2 inflammatory axis that has previously been shown to cause bone destruction. Our study provides a biological basis for pathogenesis and opens opportunities in exploiting bacterial glycans as therapeutic targets against periodontitis and a range of other infectious diseases.

  12. Towards a structure for a TSG-6.hyaluronan complex by modeling and NMR spectroscopy: insights into other members of the link module superfamily.

    Science.gov (United States)

    Blundell, Charles D; Almond, Andrew; Mahoney, David J; DeAngelis, Paul L; Campbell, Iain D; Day, Anthony J

    2005-05-06

    The Link module from human TSG-6, a hyaladherin with roles in ovulation and inflammation, has a hyaluronan (HA)-binding groove containing two adjacent tyrosine residues that are likely to form CH-pi stacking interactions with sequential rings in the sugar. We have used this observation to construct a model of a protein.HA complex, which was then tested against existing experimental information and by acquisition of new NMR data sets of [(13)C, (15)N]HA (8-mer) complexed with unlabeled protein. A major finding of this analysis was that acetamido side chains of two GlcNAc rings fit into hydrophobic pockets on either side of the adjacent tyrosines, providing a selectivity mechanism of HA over other polysaccharides. Furthermore, two basic residues have a separation that matches that of glucuronic acids in the sugar, consistent with the formation of salt bridges; NMR experiments at a range of pH values identified protein groups that titrate due to their proximity to a free carboxylate in HA. Sequence alignment and construction of homology models for all human Link modules in their HA-bound states revealed that many of these features are conserved across the superfamily, thus allowing the prediction of functionally important residues. In the case of cartilage link protein, its two Link modules were docked together (using bound HA as a guide), identifying hydrophobic residues likely to form an intra-Link module interface as well as amino acids that could be involved in supporting intermolecular interactions between link proteins and chondroitin sulfate proteoglycans. Here, we propose a mechanism for ternary complex formation that generates higher order helical structures, as may exist in cartilage aggregates.

  13. Modulation of proton transfer in the water wire of dioxolane-linked gramicidin channels by lipid membranes.

    Science.gov (United States)

    de Godoy, C M; Cukierman, S

    2001-09-01

    Proton conductance (g(H)) in single SS stereoisomers of dioxolane-linked gramicidin A (gA) channels were measured in different phospholipid bilayers at different HCl concentrations. In particular, measurements were obtained in bilayers made of 1,2-diphytanoyl 3-phosphocholine (DiPhPC) or its ethylated derivative 1,2-diphytanoyl 3-ethyl-phosphocholine (et-DiPhPC,). The difference between these phospholipids is that in et-DiPhPC one of the phosphate oxygens is covalently linked to an ethyl group and cannot be protonated. In relatively dilute acid solutions, g(H) in DiPhPC is significantly higher than in et-DiPhPC. At high acid concentrations, g(H) is the same in both diphytanoyl bilayers. Such differences in g(H) can be accounted for by surface charge effects at the membrane/solution interfaces. In the linear portion of the log g(H)-log [H] relationship, g(H) values in diphytanoyl bilayers were significantly larger (approximately 10-fold) than in neutral glyceryl monooleate (GMO) membranes. The slopes of the linear log-log relationships between g(H) and [H] in diphytanoyl and GMO bilayers are essentially the same (approximately 0.76). This slope is significantly lower than the slope of the log-log plot of proton conductivity versus proton concentration in aqueous solutions (approximately 1.00). Because the chemical composition of the membrane-channel/solution interface is strikingly different in GMO and diphytanoyl bilayers, the reduced slope in g(H)-[HCl] relationships may be a characteristic of proton transfer in the water wire inside the SS channel. Values of g(H) in diphytanoyl bilayers were also significantly larger than in membranes made of the more common biological phospholipids 1-palmitoyl 2-oleoyl phosphocholine (POPC) or 1-palmitoyl 2-oleoyl phosphoethanolamine (POPE). These differences, however, cannot be accounted for by different surface charge effects or by different internal dipole potentials. On the other hand, maximum g(H) measured in the SS channel

  14. Experimental 2.5-Gb/s QPSK WDM phase-modulated radio-over-fiber link with digital demodulation by a K-means algorithm

    DEFF Research Database (Denmark)

    Guerrero Gonzalez, Neil; Zibar, Darko; Caballero Jambrina, Antonio;

    2010-01-01

    Highest reported bit rate of 2.5 Gb/s for optically phase modulated radio-over-fiber (RoF) link, employing digital coherent detection, is demonstrated. Demodulation of 3$,times,$ 2.5 Gb/s quadrature phase-shift keying modulated wavelength-division-multiplexed RoF channels is achieved after 79 km ...... of transmission through deployed fiber. Error-free performance (bit-error rate corresponding to $10^{{-}4}$) is achieved using a digital coherent receiver in combination with a $K$-means algorithm for radio-frequency phase recovery....

  15. Experimental 2.5-Gb/s QPSK WDM phase-modulated radio-over-fiber link with digital demodulation by a K-means algorithm

    DEFF Research Database (Denmark)

    Guerrero Gonzalez, Neil; Zibar, Darko; Caballero Jambrina, Antonio

    2010-01-01

    Highest reported bit rate of 2.5 Gb/s for optically phase modulated radio-over-fiber (RoF) link, employing digital coherent detection, is demonstrated. Demodulation of 3$,times,$ 2.5 Gb/s quadrature phase-shift keying modulated wavelength-division-multiplexed RoF channels is achieved after 79 km...... of transmission through deployed fiber. Error-free performance (bit-error rate corresponding to $10^{{-}4}$) is achieved using a digital coherent receiver in combination with a $K$-means algorithm for radio-frequency phase recovery....

  16. Performance Analysis of Alternative Link-16/JTIDS Compatible Waveforms with Complex 64-Bi-Orthogonal-Keyed Modulation

    Science.gov (United States)

    2008-12-01

    signal set consists of two sets of orthogonal signals such that each signal in one set has its antipodal signal in the other set. The advantage of bi...orthogonal modulation also performs slightly better than orthogonal modulation since antipodal signal vectors have better distance properties than

  17. Enabling 4-Lane Based 400 G Client-Side Transmission Links with MultiCAP Modulation

    DEFF Research Database (Denmark)

    Tatarczak, Anna; Iglesias Olmedo, Miguel; Zuo, Tianjian;

    2015-01-01

    We propose a uniform solution for a future client-side 400 G Ethernet standard based on MultiCAP advanced modulation format, intensity modulation, and direct detection. It employs 4 local area networks-wavelength division multiplexing (LAN-WDM) lanes in 1300 nm wavelength band and parallel optics...

  18. Performance Analysis of Polarization Modulated DirectDetection Optical CDMA Systems over Turbulent FSO LinksModeled by the Gamma-Gamma Distribution

    Directory of Open Access Journals (Sweden)

    Fan Bai

    2015-01-01

    Full Text Available This paper proposes a theoretical study to characterize the transmission of optical code division multiple access (CDMA systems deploying polarization shift keying (PolSK over a free space optical (FSO link under the impact of atmospheric turbulence. In our analysis, a novel transceiver architecture for atmospheric OCDMA FSO systems based on polarization modulation with direct detection is proposed and discussed. A detailed analytical model for PolSK-OCDMA systems over a turbulent FSO link is provided. Further, we derive a closed-form bit error ratio (BER and outage probability expressions, taking into account the multiple-access interference (MAI, optical noise and the atmospheric turbulence effect on the FSO link modeled by the Gamma-Gamma distribution. Finally, the results of this study show the most significant parameters that degrade the transmission performance of the PolSK-OCDMA signal over FSO links and indicate that the proposed approach offers improved bit error ratio (BER performances compared to the on-off-keying (OOK modulation scheme in the presence of turbulence.

  19. Lifetime Estimation of DC-link Capacitors in a Single-phase Converter with an Integrated Active Power Decoupling Module

    DEFF Research Database (Denmark)

    Ma, Siyuan; Wang, Haoran; Tang, Junchaojie;

    2016-01-01

    -link capacitor capacitance can be decreased. However, few research is about the effect of DC side and AC side decoupling on the DC-link capacitor reliability considering its electro-thermal stresses. This paper presents a quantitative analysis on the lifetime of capacitors with power decoupling circuits......In single-phase inverters, DC-link capacitors are installed at the DC-link to buffer the ripple power between the AC side and DC side. Active decoupling methods introduce additional circuits at the DC side or AC side to partially or fully supply the ripple power. So that the demanded DC...

  20. Design and implementation of a web-based patient portal linked to an electronic health record designed to improve medication safety: the Patient Gateway medications module

    Directory of Open Access Journals (Sweden)

    Jeffrey Schnipper

    2008-07-01

    Full Text Available In this article we describe the background, design, and preliminary results of a medications module within Patient Gateway (PG, a patient portal linked to an electronic health record (EHR. The medications module is designed to improve the accuracy of medication lists within the EHR, reduce adverse drug events and improve patient_provider communication regarding medications and allergies in several primary care practices within a large integrated healthcare delivery network. This module allows patients to view and modify the list of medications and allergies from the EHR, report nonadherence, side effects and other medication-related problems and easily communicate this information to providers, who can verify the information and update the EHR as needed. Usage and satisfaction data indicate that patients found the module easy to use, felt that it led to their providers having more accurate information about them and enabled them to feel more prepared for their forthcoming visits. Further analyses will determine the effects of this module on important medication-related outcomes and identify further enhancements needed to improve on this approach.

  1. Radio over fiber link with adaptive order n‐QAM optical phase modulated OFDM and digital coherent detection

    DEFF Research Database (Denmark)

    Arlunno, Valeria; Borkowski, Robert; Guerrero Gonzalez, Neil

    2011-01-01

    Successful digital coherent demodulation of asynchronous optical phase‐modulated adaptive order QAM (4, 16, and 64) orthogonal frequency division multiplexing signals is achieved by a single reconfigurable digital receiver after 78 km of optical deployed fiber transmission....

  2. WiMAX radio-on-fibre in 118-km long-reach PON with deployed fibre

    DEFF Research Database (Denmark)

    Prince, Kamau; Osadchiy, Alexey Vladimirovich; Tafur Monroy, Idelfonso

    2009-01-01

    We demonstrate a radio over fibre link supporting 256-QAM / 12 Mbaud WiMAX signalling over 118-km long-reach PON with deployed fibre. Our colourless implementation uses commercially-available, low-complexity devices typically used in TDM-PON or WDM-PON.......We demonstrate a radio over fibre link supporting 256-QAM / 12 Mbaud WiMAX signalling over 118-km long-reach PON with deployed fibre. Our colourless implementation uses commercially-available, low-complexity devices typically used in TDM-PON or WDM-PON....

  3. Evaluation of High-Speed EML-based IM/DD links with PAM Modulations and Low-Complexity Equalization

    DEFF Research Database (Denmark)

    Pang, Xiaodan; Ozolins, Oskars; Gaiarin, Simone

    2017-01-01

    We experimentally evaluated up to 96 Gb/s/lambda PAM IM/DD transmissions with an EML and digital equalizations. Symbol-spaced FFE/DFEs with fewer than 10 taps are shown being sufficient for a high and stable performance over a 4 km SMF link.......We experimentally evaluated up to 96 Gb/s/lambda PAM IM/DD transmissions with an EML and digital equalizations. Symbol-spaced FFE/DFEs with fewer than 10 taps are shown being sufficient for a high and stable performance over a 4 km SMF link....

  4. Free-Space Optical Communications Link at 1550-nm using Multiple-Quantum-Well Modulating Retroreflectors in a Marine Environment

    Science.gov (United States)

    2005-05-01

    is D rec . We define a retroreflector transmit/receive optical antenna gain G retro for use in the link budget. This parameter is simply the product... Optical antenna gain. 1: Transmitting antennas,’’ Appl. Opt. 13~9!, 2134–2140 ~1974!. 21. L. C. Andrews and R. L. Phillips, Laser Beam Propagation through

  5. Impact of frequency modulation ratio on capacitor cells balancing in phase-shifted PWM based chain-link STATCOM

    DEFF Research Database (Denmark)

    Behrouzian, Ehsan; Bongiorno, Massimo; Teodorescu, Remus

    2014-01-01

    The purpose of this paper is to investigate the impact of switching harmonics on the instantaneous power that flows in the cells of a chain-link based STATCOM when using Phase-Shifted PWM. Two different cases are investigated for the converter cells: low, and high switching frequency. It is shown...... distribution among cells of the same phase leg, thus contributing to the capacitors balancing. Theoretical conclusions are validated through PSCAD simulation results....

  6. The antiphasic regulatory module comprising CDF5 and its antisense RNA FLORE links the circadian clock to photoperiodic flowering.

    Science.gov (United States)

    Henriques, Rossana; Wang, Huan; Liu, Jun; Boix, Marc; Huang, Li-Fang; Chua, Nam-Hai

    2017-07-31

    Circadian rhythms of gene expression are generated by the combinatorial action of transcriptional and translational feedback loops as well as chromatin remodelling events. Recently, long noncoding RNAs (lncRNAs) that are natural antisense transcripts (NATs) to transcripts encoding central oscillator components were proposed as modulators of core clock function in mammals (Per) and fungi (frq/qrf). Although oscillating lncRNAs exist in plants, their functional characterization is at an initial stage. By screening an Arabidopsis thaliana lncRNA custom-made array we identified CDF5 LONG NONCODING RNA (FLORE), a circadian-regulated lncRNA that is a NAT of CDF5. Quantitative real-time RT-PCR confirmed the circadian regulation of FLORE, whereas GUS-staining and flowering time evaluation were used to determine its biological function. FLORE and CDF5 antiphasic expression reflects mutual inhibition in a similar way to frq/qrf. Moreover, whereas the CDF5 protein delays flowering by directly repressing FT transcription, FLORE promotes it by repressing several CDFs (CDF1, CDF3, CDF5) and increasing FT transcript levels, indicating both cis and trans function. We propose that the CDF5/FLORE NAT pair constitutes an additional circadian regulatory module with conserved (mutual inhibition) and unique (function in trans) features, able to fine-tune its own circadian oscillation, and consequently, adjust the onset of flowering to favourable environmental conditions. © 2017 The Authors. New Phytologist © 2017 New Phytologist Trust.

  7. PRO40 is a scaffold protein of the cell wall integrity pathway, linking the MAP kinase module to the upstream activator protein kinase C.

    Directory of Open Access Journals (Sweden)

    Ines Teichert

    2014-09-01

    Full Text Available Mitogen-activated protein kinase (MAPK pathways are crucial signaling instruments in eukaryotes. Most ascomycetes possess three MAPK modules that are involved in key developmental processes like sexual propagation or pathogenesis. However, the regulation of these modules by adapters or scaffolds is largely unknown. Here, we studied the function of the cell wall integrity (CWI MAPK module in the model fungus Sordaria macrospora. Using a forward genetic approach, we found that sterile mutant pro30 has a mutated mik1 gene that encodes the MAPK kinase kinase (MAPKKK of the proposed CWI pathway. We generated single deletion mutants lacking MAPKKK MIK1, MAPK kinase (MAPKK MEK1, or MAPK MAK1 and found them all to be sterile, cell fusion-deficient and highly impaired in vegetative growth and cell wall stress response. By searching for MEK1 interaction partners via tandem affinity purification and mass spectrometry, we identified previously characterized developmental protein PRO40 as a MEK1 interaction partner. Although fungal PRO40 homologs have been implicated in diverse developmental processes, their molecular function is currently unknown. Extensive affinity purification, mass spectrometry, and yeast two-hybrid experiments showed that PRO40 is able to bind MIK1, MEK1, and the upstream activator protein kinase C (PKC1. We further found that the PRO40 N-terminal disordered region and the central region encompassing a WW interaction domain are sufficient to govern interaction with MEK1. Most importantly, time- and stress-dependent phosphorylation studies showed that PRO40 is required for MAK1 activity. The sum of our results implies that PRO40 is a scaffold protein for the CWI pathway, linking the MAPK module to the upstream activator PKC1. Our data provide important insights into the mechanistic role of a protein that has been implicated in sexual and asexual development, cell fusion, symbiosis, and pathogenicity in different fungal systems.

  8. Quaternary climate modulation of Pb isotopes in the deep Indian Ocean linked to the Himalayan chemical weathering

    Digital Repository Service at National Institute of Oceanography (India)

    Wilson, D.J.; Galy, A.; Piotrowski, A.M.; Banakar, V.K.

    ) proposed a link between Himalayan weathering changes during the Neogene and the Pb isotopic composition of the deep central Indian Ocean recorded by ferromanganese crust SS663 (Fig. 1). However, with the exception of a further study on crust DODO-232D..., the blank contribution represents only 2–1.0% of the total Pb, which in the worst case would generate an ror of ∼100 ppm for 207Pb/204Pb and ∼400 ppm for 206Pb/204Pb d 208Pb/204Pb. Since such errors are comparable to the external alytical reproducibility...

  9. Estradiol Modulates Membrane-Linked ATPases, Antioxidant Enzymes, Membrane Fluidity, Lipid Peroxidation, and Lipofuscin in Aged Rat Liver

    Directory of Open Access Journals (Sweden)

    Pardeep Kumar

    2011-01-01

    Full Text Available Free radical production and oxidative stress are known to increase in liver during aging, and may contribute to the oxidative damage. These changes increase during menopausal condition in females when the level of estradiol is decreased. The objective of this study was to observe the changes in activities of membrane linked ATPases (Na+K+ ATPase, Ca2+ ATPase, antioxidant enzymes (superoxide dismutase, glutathione-S-transferase, lipid peroxidation levels, lipofuscin content and membrane fluidity occurring in livers of female rats of 3, 12 and 24 months age groups, and to see whether these changes are restored to 3 months control levels rats after exogenous administration of 17-β-estradiol (E2. The aged rats (12 and 24 months were given subcutaneous injection of E2 (0.1 μg/g body weight daily for one month. The results obtained in the present work revealed that normal aging was associated with significant decrease in the activities of membrane linked ATPases, antioxidant enzymes, membrane fluidity and an increase in lipid peroxidation and lipofuscin content in livers of aging female rats. The present study showed that E2 treatment reversed the changes to normal levels. E2 treatment may be beneficial in preventing some of the age related changes in the liver by increasing antioxidant defenses.

  10. Integrin-linked kinase modulates longevity and thermotolerance in C. elegans through neuronal control of HSF-1.

    Science.gov (United States)

    Kumsta, Caroline; Ching, Tsui-Ting; Nishimura, Mayuko; Davis, Andrew E; Gelino, Sara; Catan, Hannah H; Yu, Xiaokun; Chu, Chu-Chiao; Ong, Binnan; Panowski, Siler H; Baird, Nathan; Bodmer, Rolf; Hsu, Ao-Lin; Hansen, Malene

    2014-06-01

    Integrin-signaling complexes play important roles in cytoskeletal organization and cell adhesion in many species. Components of the integrin-signaling complex have been linked to aging in both Caenorhabditis elegans and Drosophila melanogaster, but the mechanism underlying this function is unknown. Here, we investigated the role of integrin-linked kinase (ILK), a key component of the integrin-signaling complex, in lifespan determination. We report that genetic reduction of ILK in both C. elegans and Drosophila increased resistance to heat stress, and led to lifespan extension in C. elegans without majorly affecting cytoskeletal integrity. In C. elegans, longevity and thermotolerance induced by ILK depletion was mediated by heat-shock factor-1 (HSF-1), a major transcriptional regulator of the heat-shock response (HSR). Reduction in ILK levels increased hsf-1 transcription and activation, and led to enhanced expression of a subset of genes with roles in the HSR. Moreover, induction of HSR-related genes, longevity and thermotolerance caused by ILK reduction required the thermosensory neurons AFD and interneurons AIY, which are known to play a critical role in the canonical HSR. Notably, ILK was expressed in neighboring neurons, but not in AFD or AIY, implying that ILK reduction initiates cell nonautonomous signaling through thermosensory neurons to elicit a noncanonical HSR. Our results thus identify HSF-1 as a novel effector of the organismal response to reduced ILK levels and show that ILK inhibition regulates HSF-1 in a cell nonautonomous fashion to enhance stress resistance and lifespan in C. elegans.

  11. A mixed signal multi-chip module with high speed serial output links for the ATLAS Level-1 trigger

    CERN Document Server

    Pfeiffer, U

    2000-01-01

    We have built and tested a mixed signal multi-chip module (MCM) to be used in the Level-1 Pre-Processor system for the Calorimeter Trigger of the ATLAS experiment at CERN. The MCM performs high speed digital signal processing on four analogue input signals. Results are transmitted serially at a serial data rate of 800 MBd. Nine chips of different technologies are mounted on a four layer Cu substrate. ADC converters and serialiser chips are the major consumers of electrical power on the MCM, which amounts to 9 W for all dies. Special cut-out areas are used to dissipate heat directly to the copper substrate. In this paper we report on design criteria, chosen MCM technology for substrate and die mounting, experiences with the MCM operation and measurement results. (4 refs).

  12. SPATA2 links CYLD to the TNF-α receptor signaling complex and modulates the receptor signaling outcomes.

    Science.gov (United States)

    Wagner, Sebastian A; Satpathy, Shankha; Beli, Petra; Choudhary, Chunaram

    2016-09-01

    TNF-α is a key regulator of innate immune and proinflammatory responses. However, the composition of the TNF-α receptor-associated signaling complexes (TNF-RSC) and the architecture of the downstream signaling networks are incompletely understood. We employed quantitative mass spectrometry to demonstrate that TNF-α stimulation induces widespread protein phosphorylation and that the scope of phosphorylation expands in a temporal manner. TNF-α stimulation also induces rapid ubiquitylation of components of the TNF-RSC Temporal analysis of the TNF-RSC composition identified SPATA2 as a novel component of the TNF-RSC The predicted PUB domain in the N-terminus of SPATA2 interacts with the USP domain of CYLD, whereas the C-terminus of SPATA2 interacts with HOIP SPATA2 is required for recruitment of CYLD to the TNF-RSC Downregulation of SPATA2 augments transcriptional activation of NF-κB and inhibits TNF-α-induced necroptosis, pointing to an important function of SPATA2 in modulating the outcomes of TNF-α signaling. Taken together, our study draws a detailed map of TNF-α signaling, identifies SPATA2 as a novel component of TNF-α signaling, and provides a rich resource for further functional investigations.

  13. Rapid modulation of ultraviolet shielding in plants is influenced by solar ultraviolet radiation and linked to alterations in flavonoids.

    Science.gov (United States)

    Barnes, Paul W; Tobler, Mark A; Keefover-Ring, Ken; Flint, Stephan D; Barkley, Anne E; Ryel, Ronald J; Lindroth, Richard L

    2016-01-01

    The accumulation of ultraviolet (UV)-absorbing compounds (flavonoids and related phenylpropanoids) and the resultant decrease in epidermal UV transmittance (TUV ) are primary protective mechanisms employed by plants against potentially damaging solar UV radiation and are critical components of the overall acclimation response of plants to changing solar UV environments. Whether plants can adjust this UV sunscreen protection in response to rapid changes in UV, as occurs on a diurnal basis, is largely unexplored. Here, we use a combination of approaches to demonstrate that plants can modulate their UV-screening properties within minutes to hours, and these changes are driven, in part, by UV radiation. For the cultivated species Abelmoschus esculentus, large (30-50%) and reversible changes in TUV occurred on a diurnal basis, and these adjustments were associated with changes in the concentrations of whole-leaf UV-absorbing compounds and several quercetin glycosides. Similar results were found for two other species (Vicia faba and Solanum lycopersicum), but no such changes were detected in Zea mays. These findings reveal a much more dynamic UV-protection mechanism than previously recognized, raise important questions concerning the costs and benefits of UV-protection strategies in plants and have practical implications for employing UV to enhance crop vigor and quality in controlled environments.

  14. Simultaneous even- and third-order distortion suppression in a microwave photonic link based on orthogonal polarization modulation, balanced detection, and optical sideband filtering.

    Science.gov (United States)

    Han, Xiuyou; Chen, Xiang; Yao, Jianping

    2016-06-27

    A microwave photonic link (MPL) with simultaneous suppression of the even-order and third-order distortions using a polarization modulator (PolM), an optical bandpass filter (OBPF), and a balanced photodetector (BPD) is proposed and experimentally demonstrated. The even-order distortions are suppressed by utilizing orthogonal polarization modulation based on the PolM and balanced differential detection based on the BPD. The third-order distortions (IMD3) are suppressed by optimizing the spectral response of the OBPF with an optimal power ratio between the optical carrier and the sidebands of the phase-modulated signals from the PolM. Since the suppression of the IMD3 is achieved when the MPL is optimized for even-order distortion suppression, the proposed MPL can operate with simultaneous suppression of the even-order and third-order distortions. The proposed MPL is analyzed theoretically and is verified by an experiment. For a two-tone RF signal of f1 = 10 GHz and f2 = 19.95 GHz, the spurious-free dynamic range (SFDR2) is enhanced by 23.4 dB for the second harmonic (2f1), and 29.1 and 27.6 dB for the second intermodulation (f2-f1 and f1 + f2), as compared with a conventional MPL. For a two-tone RF signal of f1 = 9.95 GHz and f2 = 10 GHz, the SFDR3 is increased by 13.1 dB as compared with a conventional MPL.

  15. Oma1 Links Mitochondrial Protein Quality Control and TOR Signaling To Modulate Physiological Plasticity and Cellular Stress Responses.

    Science.gov (United States)

    Bohovych, Iryna; Kastora, Stavroula; Christianson, Sara; Topil, Danelle; Kim, Heejeong; Fangman, Teresa; Zhou, You J; Barrientos, Antoni; Lee, Jaekwon; Brown, Alistair J P; Khalimonchuk, Oleh

    2016-09-01

    A network of conserved proteases known as the intramitochondrial quality control (IMQC) system is central to mitochondrial protein homeostasis and cellular health. IMQC proteases also appear to participate in establishment of signaling cues for mitochondrion-to-nucleus communication. However, little is known about this process. Here, we show that in Saccharomyces cerevisiae, inactivation of the membrane-bound IMQC protease Oma1 interferes with oxidative-stress responses through enhanced production of reactive oxygen species (ROS) during logarithmic growth and reduced stress signaling via the TORC1-Rim15-Msn2/Msn4 axis. Pharmacological or genetic prevention of ROS accumulation in Oma1-deficient cells restores this defective TOR signaling. Additionally, inactivation of the Oma1 ortholog in the human fungal pathogen Candida albicans also alters TOR signaling and, unexpectedly, leads to increased resistance to neutrophil killing and virulence in the invertebrate animal model Galleria mellonella Our findings reveal a novel and evolutionarily conserved link between IMQC and TOR-mediated signaling that regulates physiological plasticity and pancellular oxidative-stress responses.

  16. Allosteric modulation of the HIV-1 gp120-gp41 association site by adjacent gp120 variable region 1 (V1 N-glycans linked to neutralization sensitivity.

    Directory of Open Access Journals (Sweden)

    Heidi E Drummer

    Full Text Available The HIV-1 gp120-gp41 complex, which mediates viral fusion and cellular entry, undergoes rapid evolution within its external glycan shield to enable escape from neutralizing antibody (NAb. Understanding how conserved protein determinants retain functionality in the context of such evolution is important for their evaluation and exploitation as potential drug and/or vaccine targets. In this study, we examined how the conserved gp120-gp41 association site, formed by the N- and C-terminal segments of gp120 and the disulfide-bonded region (DSR of gp41, adapts to glycan changes that are linked to neutralization sensitivity. To this end, a DSR mutant virus (K601D with defective gp120-association was sequentially passaged in peripheral blood mononuclear cells to select suppressor mutations. We reasoned that the locations of suppressors point to structural elements that are functionally linked to the gp120-gp41 association site. In culture 1, gp120 association and viral replication was restored by loss of the conserved glycan at Asn¹³⁶ in V1 (T138N mutation in conjunction with the L494I substitution in C5 within the association site. In culture 2, replication was restored with deletion of the N¹³⁹INN sequence, which ablates the overlapping Asn¹⁴¹-Asn¹⁴²-Ser-Ser potential N-linked glycosylation sequons in V1, in conjunction with D601N in the DSR. The 136 and 142 glycan mutations appeared to exert their suppressive effects by altering the dependence of gp120-gp41 interactions on the DSR residues, Leu⁵⁹³, Trp⁵⁹⁶ and Lys⁶⁰¹. The 136 and/or 142 glycan mutations increased the sensitivity of HIV-1 pseudovirions to the glycan-dependent NAbs 2G12 and PG16, and also pooled IgG obtained from HIV-1-infected individuals. Thus adjacent V1 glycans allosterically modulate the distal gp120-gp41 association site. We propose that this represents a mechanism for functional adaptation of the gp120-gp41 association site to an evolving glycan

  17. Experimental demonstration of real-time adaptively modulated DDO-OFDM systems with a high spectral efficiency up to 5.76bit/s/Hz transmission over SMF links.

    Science.gov (United States)

    Chen, Ming; He, Jing; Tang, Jin; Wu, Xian; Chen, Lin

    2014-07-28

    In this paper, a FPGAs-based real-time adaptively modulated 256/64/16QAM-encoded base-band OFDM transceiver with a high spectral efficiency up to 5.76bit/s/Hz is successfully developed, and experimentally demonstrated in a simple intensity-modulated direct-detection optical communication system. Experimental results show that it is feasible to transmit a raw signal bit rate of 7.19Gbps adaptively modulated real-time optical OFDM signal over 20km and 50km single mode fibers (SMFs). The performance comparison between real-time and off-line digital signal processing is performed, and the results show that there is a negligible power penalty. In addition, to obtain the best transmission performance, direct-current (DC) bias voltage for MZM and launch power into optical fiber links are explored in the real-time optical OFDM systems.

  18. Na+/K+-ATPase is present in scrapie-associated fibrils, modulates PrP misfolding in vitro and links PrP function and dysfunction.

    Directory of Open Access Journals (Sweden)

    James F Graham

    Full Text Available Transmissible spongiform encephalopathies are characterised by widespread deposition of fibrillar and/or plaque-like forms of the prion protein. These aggregated forms are produced by misfolding of the normal prion protein, PrP(C, to the disease-associated form, PrP(Sc, through mechanisms that remain elusive but which require either direct or indirect interaction between PrP(C and PrP(Sc isoforms. A wealth of evidence implicates other non-PrP molecules as active participants in the misfolding process, to catalyse and direct the conformational conversion of PrP(C or to provide a scaffold ensuring correct alignment of PrP(C and PrP(Sc during conversion. Such molecules may be specific to different scrapie strains to facilitate differential prion protein misfolding. Since molecular cofactors may become integrated into the growing protein fibril during prion conversion, we have investigated the proteins contained in prion disease-specific deposits by shotgun proteomics of scrapie-associated fibrils (SAF from mice infected with 3 different strains of mouse-passaged scrapie. Concomitant use of negative control preparations allowed us to identify and discount proteins that are enriched non-specifically by the SAF isolation protocol. We found several proteins that co-purified specifically with SAF from infected brains but none of these were reproducibly and demonstrably specific for particular scrapie strains. The α-chain of Na(+/K(+-ATPase was common to SAF from all 3 strains and we tested the ability of this protein to modulate in vitro misfolding of recombinant PrP. Na(+/K(+-ATPase enhanced the efficiency of disease-specific conversion of recombinant PrP suggesting that it may act as a molecular cofactor. Consistent with previous results, the same protein inhibited fibrillisation kinetics of recombinant PrP. Since functional interactions between PrP(C and Na(+/K(+-ATPase have previously been reported in astrocytes, our data highlight this molecule as

  19. Extending the Linear Modulation Range to the Full Base Speed Using a Single DC-Link Multilevel Inverter With Capacitor-Fed H-Bridges for IM Drives

    DEFF Research Database (Denmark)

    Rahul, Arun; Pramanick, Sumit; Kaarthik, R. Sudharshan

    2017-01-01

    of the inverter can be increased from 0.577 to 0.637Vdc without increasing the dc bus voltage and without exceeding the induction motor voltage rating. This new technique makes use of cascaded inverter pole voltage redundancy and property of the space vector structure for its operation. Using this, the induction......In this paper, a new space vector pulse width modulation method to extend the linear modulation range of a cascaded five level inverter topology with a single dc supply is presented. Using this method, the inverter can be controlled linearly and the peak phase fundamental output voltage...... motor drive can be operated till the full speed range (0-50 Hz) with the elimination of lower order harmonics in the phase voltage and phase current. The five-level topology presented in this paper is realized by cascading a two-level inverter and two full bridge modules with floating capacitors...

  20. Modification of EGF-like module 1 of thrombospondin-1, an animal extracellular protein, by O-linked N-acetylglucosamine.

    Directory of Open Access Journals (Sweden)

    Brian R Hoffmann

    Full Text Available Thrombospondin-1 (TSP-1 is known to be subject to three unusual carbohydrate modifications: C-mannosylation, O-fucosylation, and O-glucosylation. We now describe a fourth: O-β-N-acetylglucosaminylation. Previously, O-β-N-acetylglucosamine (O-β-GlcNAc was found on a threonine in the loop between the fifth and sixth cysteines of the 20(th epidermal growth factor (EGF-like module of Drosophila Notch. A BLAST search based on the Drosophila Notch loop sequence identified a number of human EGF-like modules that contain a similar sequence, including EGF-like module 1 of TSP-1 and its homolog, TSP-2. TSP-1, which has a potentially modifiable serine in the loop, reacted in immuno-blots with the CTD110.6 anti-O-GlcNAc antibody. Antibody reactivity was diminished by treatment of TSP-1 with β-N-acetylhexosaminidase. TSP-2, which lacks a potentially modifiable serine/threonine in the loop, did not react with CTD110.6. Analysis of tandem modules of TSP-1 localized reactivity of CTD110.6 to EGF-like module 1. Top-down mass spectrometric analysis of EGF-like module 1 demonstrated the expected modifications with glucose (+162 Da and xylose (+132 Da separately from modification with N-acetyl hexosamine (+203 Da. Mass spectrometric sequence analysis localized the +203-Da modification to Ser580 in the sequence (575CPPGYSGNGIQC(586. These results demonstrate that O-β-N-acetylglucosaminylation can occur on secreted extracellular matrix proteins as well as on cell surface proteins.

  1. Simplified flexible-PON upstream transmission using pulse position modulation at ONU and DSP-enabled soft-combining at OLT for adaptive link budgets.

    Science.gov (United States)

    Liu, Xiang; Effenberger, Frank; Chand, Naresh

    2015-03-09

    We demonstrate a flexible modulation and detection scheme for upstream transmission in passive optical networks using pulse position modulation at optical network unit, facilitating burst-mode detection with automatic decision threshold tracking, and DSP-enabled soft-combining at optical line terminal. Adaptive receiver sensitivities of -33.1 dBm, -36.6 dBm and -38.3 dBm at a bit error ratio of 10(-4) are respectively achieved for 2.5 Gb/s, 1.25 Gb/s and 625 Mb/s after transmission over a 20-km standard single-mode fiber without any optical amplification.

  2. Optical phase-modulated radio-over-fiber links with k-means algorithm for digital demodulation of 8PSK subcarrier multiplexed signals

    DEFF Research Database (Denmark)

    Guerrero Gonzalez, Neil; Zibar, Darko; Yu, Xianbin

    2010-01-01

    A k-means algorithm for phase recovery of three, 50 Mbaud, 8PSK subcarrier multiplexed signals at 5 GHz for optical phase-modulated radio-over-fiber is proposed and experimentally demonstrated after 40 km of single mode fiber transmission......A k-means algorithm for phase recovery of three, 50 Mbaud, 8PSK subcarrier multiplexed signals at 5 GHz for optical phase-modulated radio-over-fiber is proposed and experimentally demonstrated after 40 km of single mode fiber transmission...

  3. High-speed 1550 nm VCSEL data transmission link employing 25 Gbaud 4-PAM modulation and Hard Decision Forward Error Correction

    DEFF Research Database (Denmark)

    Rodes Lopez, Roberto; Mueller, M.; Li, Bomin

    2013-01-01

    Current short-range optical interconnects capacity is moving from 100 Gb/s to 400 Gb/s and beyond. Directly modulation of several laser sources is used to minimize bandwidth limitations of current optical and electrical components. Either this total capacity is provided by wavelengthdivision- mul...

  4. Adaptive antenna system for OFDMA WiMAX radio-over-fiber links using a directly modulated R-SOA and optical filtering

    DEFF Research Database (Denmark)

    Presi, Marco; Prince, Kamau; Chiuchiarelli, Andrea;

    2009-01-01

    We implement an adaptive beam steering system based on a directly-modulated unseeded reflective SOA. this system allows the distribution of 2.4 GHz 64-QAM OFDMA signals with 2048-subcarriers (72 Mb/s) satisfying the IEEE 802.16e specifications...

  5. Adaptive antenna system for OFDMA WiMAX radio-over-fiber links using a directly modulated R-SOA and optical filtering

    DEFF Research Database (Denmark)

    Presi, Marco; Prince, Kamau; Chiuchiarelli, Andrea

    2009-01-01

    We implement an adaptive beam steering system based on a directly-modulated unseeded reflective SOA. this system allows the distribution of 2.4 GHz 64-QAM OFDMA signals with 2048-subcarriers (72 Mb/s) satisfying the IEEE 802.16e specifications...

  6. Selective activation of mitomycin A by thiols to form DNA cross-links and monoadducts: biochemical basis for the modulation of mitomycin cytotoxicity by the quinone redox potential.

    Science.gov (United States)

    Paz, M M; Das, A; Palom, Y; He, Q Y; Tomasz, M

    2001-08-16

    Mitomycin A (MA) but not mitomycin C (MC) cross-linked linearized (32)P-pBR322 DNA in the presence of dithiothreitol (DTT) or glutathione (GSH), as shown by a sensitive DNA cross-link assay. Incubation of calf-thymus DNA with MA and DTT or mercaptoethanol (MER) resulted in the formation of MA-DNA adducts, which were isolated from nuclease digests of the drug-DNA complexes by HPLC. The adducts were characterized by their UV absorption spectra, electrospray ionization mass spectrometry (ESIMS), and facile conversion from 7-methoxy- to 7-amino-substituted mitosene type adducts upon 10% NH(4)OH treatment, which were identical with known adducts of MC. Both DNA interstrand and intrastrand cross-link adducts, linking two deoxyguanosine residues at N(2), as well as several deoxyguanosine-N(2) monoadducts of MA, were identified. No DNA adducts were formed with MC under the same conditions. A specificity of DNA cross-link formation for the CpG sequence was observed using 12-mer synthetic oligodeoxyribonucleotides as substrates and as DNA sequence models, in analogy to the known CpG sequence specificity of MC-induced DNA cross-links. MA is known to be more cytotoxic by 2-3 orders of magnitude than MC, and this property correlates with redox potentials of MA (-0.19 V) and MA analogues that are higher than those of MC (-0.40 V) and its analogues. It is suggested that the biochemical basis for the higher cytotoxic potency of MA is MA's propensity to be reductively activated by cellular thiols while MC is resistant to thiol activation. This distinction is probably derived from the large difference between the quinone redox potentials of the two drugs.

  7. Space Vector Modulation for DC-Link Current Ripple Reduction in Back-To-Back Current Source Converters for Microgrid Applications

    DEFF Research Database (Denmark)

    Guo, Xiaoqiang; Xu, David; Guerrero, Josep M.

    2015-01-01

    instability. Conventionally, with a given switching frequency and rated voltage, the current ripple can be reduced by increasing the dc-link inductor, but it leads to bulky size, high cost and slow dynamic response. In order to solve this problem, this paper reveals that the current ripple can......Back-to-back converters have been typically used to interconnect the microgrids. For a back-to-back current source converter, the dc-link current ripple is one of the important parameters. A large ripple will cause the electromagnetic interference, undesirable high-frequency losses, and system...

  8. Linking Dimensional Models of Internalizing Psychopathology to Neurobiological Systems: Affect-Modulated Startle as an Indicator of Fear and Distress Disorders and Affiliated Traits

    Science.gov (United States)

    Vaidyanathan, Uma; Patrick, Christopher J.; Cuthbert, Bruce N.

    2009-01-01

    Integrative hierarchical models have sought to account for the extensive comorbidity between various internalizing disorders in terms of broad individual difference factors these disorders share. However, such models have been developed largely on the basis of self-report and diagnostic symptom data. Toward the goal of linking such models to…

  9. Scandinavian links

    DEFF Research Database (Denmark)

    Matthiessen, Christian Wichmann; Knowles, Richard D.

    2014-01-01

    centres, one joins more thinly populated regions, and the last one links peripheral areas. Two of them (The Great Belt Link and the Oresund Link) have been constructed and are in full operation. The third (the Fehmarnbelt Link) has been decided 2008 on bilateral government level. The three links...

  10. Ergodic channel capacity of spatial correlated multiple-input multiple-output free space optical links using multipulse pulse-position modulation

    Science.gov (United States)

    Wang, Huiqin; Wang, Xue; Cao, Minghua

    2017-02-01

    The spatial correlation extensively exists in the multiple-input multiple-output (MIMO) free space optical (FSO) communication systems due to the channel fading and the antenna space limitation. Wilkinson's method was utilized to investigate the impact of spatial correlation on the MIMO FSO communication system employing multipulse pulse-position modulation. Simulation results show that the existence of spatial correlation reduces the ergodic channel capacity, and the reception diversity is more competent to resist this kind of performance degradation.

  11. The link in Linking

    Science.gov (United States)

    Caldwell, Jane C; Chiale, Pablo A; Gonzalez, Mario D; Baranchuk, Adrian

    2013-01-01

    We present 2 cases of the slow-fast form of AVNRT with initially narrow QRS complexes followed by sudden unexpected transition to persistently wide QRS complexes due to aberrant intraventricular conduction. Introduction of a properly timed extrastimulus in one case and critical oscillations in cycle length due to short-long coupling in the second case set the stage for the initial bundle branch block. However, persistence of the aberrancy pattern once the initial event abated was maintained by the "linking" phenomenon. Delayed, retrograde concealed activation from the contralateral bundle branch perpetuated the initial bundle branch block. PMID:23840106

  12. TRIM32 protein modulates type I interferon induction and cellular antiviral response by targeting MITA/STING protein for K63-linked ubiquitination.

    Science.gov (United States)

    Zhang, Jing; Hu, Ming-Ming; Wang, Yan-Yi; Shu, Hong-Bing

    2012-08-17

    Viral infection activates several transcription factors including NF-κB and IRF3, which collaborate to induce type I interferons (IFNs) and innate antiviral response. MITA (also called STING) is a critical adaptor protein that links virus-sensing receptors to IRF3 activation upon infection by both RNA and DNA pathogens. Here we show that the E3 ubiquitin ligase tripartite motif protein 32 (TRIM32) ubiquitinated MITA and dramatically enhanced MITA-mediated induction of IFN-β. Overexpression of TRIM32 potentiated virus-triggered IFNB1 expression and cellular antiviral response. Consistently, knockdown of TRIM32 had opposite effects. TRIM32 interacted with MITA, and was located at the mitochondria and endoplasmic reticulum. TRIM32 targeted MITA for K63-linked ubiquitination at K20/150/224/236 through its E3 ubiquitin ligase activity, which promoted the interaction of MITA with TBK1. These findings suggest that TRIM32 is an important regulatory protein for innate immunity against both RNA and DNA viruses by targeting MITA for K63-linked ubiquitination and downstream activation.

  13. Role of the oceanic bridge in linking the 18.6 year modulation of tidal mixing and long-term SST change in the North Pacific

    Science.gov (United States)

    Osafune, S.; Masuda, S.; Sugiura, N.

    2014-10-01

    The impact of the 18.6 year modulation of tidal mixing on sea surface temperature (SST) in the North Pacific is investigated in a comparative study using an ocean data synthesis system. We show that remote impact through a slow ocean response can make a significant contribution to the observed bidecadal variation in wintertime SST near the center of action of the Pacific Decadal Oscillation in the eastern Pacific. A comparative data synthesis experiment showed that the modified SST variation is amplified by bidecadal variation in the westerly wind. This relationship between SST and wind variations is consistent with an observed air-sea coupled mode in the extratropics, which suggests that a midlatitude air-sea interaction plays an important role in enhancing the climate signal of the 18.6 year modulation. This result supports the hypothesis that the 18.6 year tidal cycle influences long-term variability in climate; thus, knowledge of this cycle could contribute toward improving decadal predictions of climate.

  14. Phosphorylation of actin-binding protein (ABP-280; filamin) by tyrosine kinase p56lck modulates actin filament cross-linking.

    Science.gov (United States)

    Pal Sharma, C; Goldmann, Wolfgang H

    2004-01-01

    Actin-binding protein (ABP-280; filamin) is a phosphoprotein present in the periphery of the cytoplasm where it can cross-link actin filaments, associate with lipid membranes, and bind to membrane surface receptors. Given its function and localization in the cell, we decided to investigate the possibility of whether it serves as substrate for p56lck, a lymphocyte-specific member of the src family of protein tyrosine kinases associated with cell surface glycoproteins. The interaction of p56lck with membrane glycoproteins is important for cell development and functional activation. Here, we show that purified p56lck interacts and catalyzes in vitro kinase reactions. Tyrosine phosphorylation by p56lck is restricted to a single peptide of labeled ABP-280 shown by protease digest. The addition of phorbol ester to cells results in the inhibition of phosphorylation of ABP-280 by p56lck. These results show a decrease in phosphorylation suggesting conformationally induced regulation. Dynamic light scattering confirmed increased actin filament cross-linking due to phosphorylation of ABP-280 by p56lck.

  15. Clinacanthus nutans Extracts Modulate Epigenetic Link to Cytosolic Phospholipase A2 Expression in SH-SY5Y Cells and Primary Cortical Neurons.

    Science.gov (United States)

    Tan, Charlene Siew-Hon; Ho, Christabel Fung-Yih; Heng, Swan-Ser; Wu, Jui-Sheng; Tan, Benny Kwong-Huat; Ng, Yee-Kong; Sun, Grace Y; Lin, Teng-Nan; Ong, Wei-Yi

    2016-09-01

    Clinacanthus nutans Lindau (C. nutans), commonly known as Sabah Snake Grass in southeast Asia, is widely used in folk medicine due to its analgesic, antiviral, and anti-inflammatory properties. Our recent study provided evidence for the regulation of cytosolic phospholipase A2 (cPLA2) mRNA expression by epigenetic factors (Tan et al. in Mol Neurobiol. doi: 10.1007/s12035-015-9314-z , 2015). This enzyme catalyzes the release of arachidonic acid from glycerophospholipids, and formation of pro-inflammatory eicosanoids or toxic lipid peroxidation products such as 4-hydroxynonenal. In this study, we examined the effects of C. nutans ethanol leaf extracts on epigenetic regulation of cPLA2 mRNA expression in SH-SY5Y human neuroblastoma cells and mouse primary cortical neurons. C. nutans modulated induction of cPLA2 expression in SH-SY5Y cells by histone deacetylase (HDAC) inhibitors, MS-275, MC-1568, and TSA. C. nutans extracts also inhibited histone acetylase (HAT) activity. Levels of cPLA2 mRNA expression were increased in primary cortical neurons subjected to 0.5-h oxygen-glucose deprivation injury (OGD). This increase was significantly inhibited by C. nutans treatment. Treatment of primary neurons with the HDAC inhibitor MS-275 augmented OGD-induced cPLA2 mRNA expression, and this increase was modulated by C. nutans extracts. OGD-stimulated increase in cPLA2 mRNA expression was also reduced by a Tip60 HAT inhibitor, NU9056. In view of a key role of cPLA2 in the production of pro-inflammatory eicosanoids and free radical damage, and the fact that epigenetic effects on genes are often long-lasting, results suggest a role for C. nutans and phytochemicals to inhibit the production of arachidonic acid-derived pro-inflammatory eicosanoids and chronic inflammation, through epigenetic regulation of cPLA2 expression.

  16. Role of protein tyrosine phosphatases in the modulation of insulin signaling and their implication in the pathogenesis of obesity-linked insulin resistance.

    Science.gov (United States)

    Xu, Elaine; Schwab, Michael; Marette, André

    2014-03-01

    Insulin resistance is a major disorder that links obesity to type 2 diabetes mellitus (T2D). It involves defects in the insulin actions owing to a reduced ability of insulin to trigger key signaling pathways in major metabolic tissues. The pathogenesis of insulin resistance involves several inhibitory molecules that interfere with the tyrosine phosphorylation of the insulin receptor and its downstream effectors. Among those, growing interest has been developed toward the protein tyrosine phosphatases (PTPs), a large family of enzymes that can inactivate crucial signaling effectors in the insulin signaling cascade by dephosphorylating their tyrosine residues. Herein we briefly review the role of several PTPs that have been shown to be implicated in the regulation of insulin action, and then focus on the Src homology 2 (SH2) domain-containing SHP1 and SHP2 enzymes, since recent reports have indicated major roles for these PTPs in the control of insulin action and glucose metabolism. Finally, the therapeutic potential of targeting PTPs for combating insulin resistance and alleviating T2D will be discussed.

  17. The cycad genotoxin MAM modulates brain cellular pathways involved in neurodegenerative disease and cancer in a DNA damage-linked manner.

    Directory of Open Access Journals (Sweden)

    Glen E Kisby

    Full Text Available Methylazoxymethanol (MAM, the genotoxic metabolite of the cycad azoxyglucoside cycasin, induces genetic alterations in bacteria, yeast, plants, insects and mammalian cells, but adult nerve cells are thought to be unaffected. We show that the brains of adult C57BL6 wild-type mice treated with a single systemic dose of MAM acetate display DNA damage (O⁶-methyldeoxyguanosine lesions, O⁶-mG that remains constant up to 7 days post-treatment. By contrast, MAM-treated mice lacking a functional gene encoding the DNA repair enzyme O⁶-mG DNA methyltransferase (MGMT showed elevated O⁶-mG DNA damage starting at 48 hours post-treatment. The DNA damage was linked to changes in the expression of genes in cell-signaling pathways associated with cancer, human neurodegenerative disease, and neurodevelopmental disorders. These data are consistent with the established developmental neurotoxic and carcinogenic properties of MAM in rodents. They also support the hypothesis that early-life exposure to MAM-glucoside (cycasin has an etiological association with a declining, prototypical neurodegenerative disease seen in Guam, Japan, and New Guinea populations that formerly used the neurotoxic cycad plant for food or medicine, or both. These findings suggest environmental genotoxins, specifically MAM, target common pathways involved in neurodegeneration and cancer, the outcome depending on whether the cell can divide (cancer or not (neurodegeneration. Exposure to MAM-related environmental genotoxins may have relevance to the etiology of related tauopathies, notably, Alzheimer's disease.

  18. The cycad genotoxin MAM modulates brain cellular pathways involved in neurodegenerative disease and cancer in a DNA damage-linked manner.

    Science.gov (United States)

    Kisby, Glen E; Fry, Rebecca C; Lasarev, Michael R; Bammler, Theodor K; Beyer, Richard P; Churchwell, Mona; Doerge, Daniel R; Meira, Lisiane B; Palmer, Valerie S; Ramos-Crawford, Ana-Luiza; Ren, Xuefeng; Sullivan, Robert C; Kavanagh, Terrance J; Samson, Leona D; Zarbl, Helmut; Spencer, Peter S

    2011-01-01

    Methylazoxymethanol (MAM), the genotoxic metabolite of the cycad azoxyglucoside cycasin, induces genetic alterations in bacteria, yeast, plants, insects and mammalian cells, but adult nerve cells are thought to be unaffected. We show that the brains of adult C57BL6 wild-type mice treated with a single systemic dose of MAM acetate display DNA damage (O⁶-methyldeoxyguanosine lesions, O⁶-mG) that remains constant up to 7 days post-treatment. By contrast, MAM-treated mice lacking a functional gene encoding the DNA repair enzyme O⁶-mG DNA methyltransferase (MGMT) showed elevated O⁶-mG DNA damage starting at 48 hours post-treatment. The DNA damage was linked to changes in the expression of genes in cell-signaling pathways associated with cancer, human neurodegenerative disease, and neurodevelopmental disorders. These data are consistent with the established developmental neurotoxic and carcinogenic properties of MAM in rodents. They also support the hypothesis that early-life exposure to MAM-glucoside (cycasin) has an etiological association with a declining, prototypical neurodegenerative disease seen in Guam, Japan, and New Guinea populations that formerly used the neurotoxic cycad plant for food or medicine, or both. These findings suggest environmental genotoxins, specifically MAM, target common pathways involved in neurodegeneration and cancer, the outcome depending on whether the cell can divide (cancer) or not (neurodegeneration). Exposure to MAM-related environmental genotoxins may have relevance to the etiology of related tauopathies, notably, Alzheimer's disease.

  19. Serotonergic neural links from the dorsal raphe nucleus modulate defensive behaviours organised by the dorsomedial hypothalamus and the elaboration of fear-induced antinociception via locus coeruleus pathways.

    Science.gov (United States)

    Biagioni, Audrey Francisco; de Freitas, Renato Leonardo; da Silva, Juliana Almeida; de Oliveira, Rithiele Cristina; de Oliveira, Ricardo; Alves, Vani Maria; Coimbra, Norberto Cysne

    2013-04-01

    Decrease of γ-aminobutyric acid (GABA)-mediated neurotransmission in the dorsomedial hypothalamus (DMH) evokes instinctive fear-like responses. The aim of the present study was to investigate the involvement of the serotonin (5-HT)- and norepinephrine-mediated pathways of the endogenous pain inhibitory system, including the dorsal raphe nucleus (DRN) and the locus coeruleus (LC), in the defensive responses and antinociceptive processes triggered by the blockade of GABAergic receptors in the DMH. The intra-hypothalamic microinjection of the GABA(A) receptor antagonist bicuculline (40 ng/200 nL) elicited elaborate defensive behaviours interspersed with exploratory responses. This escape behaviour was followed by significantly increased pain thresholds, a phenomenon known as fear-induced antinociception. Furthermore, at 5 and 14 days after DRN serotonin-containing neurons were damaged using the selective neurotoxin 5,7-dihydroxytryptamine (5,7-DHT), the frequency and duration of alertness and escape behaviour evoked by the GABA(A) receptor blockade in the DMH decreased, as well as fear-induced antinociception. Pre-treatment with the non-selective 5-HT receptor antagonist methysergide, the 5-HT(2A/2C) receptor antagonist ketanserin and the 5-HT(2A) receptor selective antagonist R-96544 in the LC also decreased fear-induced antinociception, without significant changes in the expression of defensive behaviours. These data suggest that the serotonergic neurons of the DRN are directly involved in the organisation of defensive responses as well as in the elaboration of the innate fear-induced antinociception. However, serotonin-mediated inputs from the NDR to the LC modulate only fear-induced antinociception and not the defensive behaviours evoked by GABA(A) receptor blockade in the DMH.

  20. Effect of atmospheric turbulence on the bit error probability of a space to ground near infrared laser communications link using binary pulse position modulation and an avalanche photodiode detector

    Science.gov (United States)

    Safren, H. G.

    1987-01-01

    The effect of atmospheric turbulence on the bit error rate of a space-to-ground near infrared laser communications link is investigated, for a link using binary pulse position modulation and an avalanche photodiode detector. Formulas are presented for the mean and variance of the bit error rate as a function of signal strength. Because these formulas require numerical integration, they are of limited practical use. Approximate formulas are derived which are easy to compute and sufficiently accurate for system feasibility studies, as shown by numerical comparison with the exact formulas. A very simple formula is derived for the bit error rate as a function of signal strength, which requires only the evaluation of an error function. It is shown by numerical calculations that, for realistic values of the system parameters, the increase in the bit error rate due to turbulence does not exceed about thirty percent for signal strengths of four hundred photons per bit or less. The increase in signal strength required to maintain an error rate of one in 10 million is about one or two tenths of a db.

  1. A mixture of oleic, erucic and conjugated linoleic acids modulates cerebrospinal fluid inflammatory markers and improve somatosensorial evoked potential in X-linked adrenoleukodystrophy female carriers.

    Science.gov (United States)

    Cappa, Marco; Bizzarri, Carla; Petroni, Anna; Carta, Gianfranca; Cordeddu, Lina; Valeriani, Massimiliano; Vollono, Catello; De Pasquale, Loredana; Blasevich, Milena; Banni, Sebastiano

    2012-09-01

    X-linked adrenoleukodystrophy is a rare inherited demyelinating disorder characterized by an abnormal accumulation of very long chain fatty acids, mainly hexacosanoic acid (26:0), due to a mutation of the gene encoding for a peroxisomal membrane protein. The only available, and partially effective, therapeutic treatment consists of dietary intake of a 4:1 mixture of triolein and trierucin, called Lorenzo's oil (LO), targeted to inhibit the elongation of docosanoic acid (22:0) to 26:0. In this study we tested whether, besides inhibiting elongation, an enhancement of peroxisomal beta oxidation induced by conjugated linoleic acid (CLA), will improve somatosensory evoked potentials and modify inflammatory markers in adrenoleukodystrophy females carriers. We enrolled five heterozygous women. They received a mixture of LO (40 g/day) with CLA (5 g/day) for 2 months. The therapeutic efficacy was evaluated by the means of plasma levels of 26:0, 26:0/22:0 ratio, modification of cerebrospinal fluid (CSF) inflammatory markers and somatosensory evoked potentials. Changes of fatty acid profile, and in particular CLA incorporation, were also evaluated in CSF and plasma. The results showed that CLA promptly passes the blood brain barrier and the mixture was able to lower both 26:0 and 26:0/22:0 ratio in plasma. The mixture improved somatosensory evoked potentials, which were previously found unchanged or worsened with dietary LO alone, and reduced IL-6 levels in CSF in three out of five patients. Our data suggest that the synergic activity of CLA and LO, by enhancing peroxisomal beta-oxidation and preventing 26:0 formation, improves the somatosensory evoked potentials and reduces neuroinflammation.

  2. Microwaves photonic links components and circuits

    CERN Document Server

    Rumelhard, Christian; Billabert, Anne-Laure

    2013-01-01

    This book presents the electrical models for the different elements of a photonic microwave link like lasers, external modulators, optical fibers, photodiodes and phototransistors. The future trends of these components are also introduced: lasers to VCSEL, external modulators to electro-absorption modulators, glass optical fibers to plastic optical fibers, photodiodes to UTC photodiodes or phototransistors. It also describes an original methodology to evaluate the performance of a microwave photonic link, based on the developed elcetrical models, that can be easily incorporated in

  3. Analysis of second order harmonic distortion due to transmitter non-linearity and chromatic and modal dispersion of optical OFDM SSB modulated signals in SMF-MMF fiber links

    Science.gov (United States)

    Patel, Dhananjay; Singh, Vinay Kumar; Dalal, U. D.

    2017-01-01

    Single mode fibers (SMF) are typically used in Wide Area Networks (WAN), Metropolitan Area Networks (MAN) and also find applications in Radio over Fiber (RoF) architectures supporting data transmission in Fiber to the Home (FTTH), Remote Antenna Units (RAUs), in-building networks etc. Multi-mode fibers (MMFs) with low cost, ease of installation and low maintenance are predominantly (85-90%) deployed in-building networks providing data access in local area networks (LANs). The transmission of millimeter wave signals through the SMF in WAN and MAN, along with the reuse of MMF in-building networks will not levy fiber reinstallation cost. The transmission of the millimeter waves experiences signal impairments due to the transmitter non-linearity and modal dispersion of the MMF. The MMF exhibiting large modal dispersion limits the bandwidth-length product of the fiber. The second and higher-order harmonics present in the optical signal fall within the system bandwidth. This causes degradation in the received signal and an unwanted radiation of power at the RAU. The power of these harmonics is proportional to the non-linearity of the transmitter and the modal dispersion of the MMF and should be maintained below the standard values as per the international norms. In this paper, a mathematical model is developed for Second-order Harmonic Distortion (HD2) generated due to non-linearity of the transmitter and chromatic-modal dispersion of the SMF-MMF optic link. This is also verified using a software simulation. The model consists of a Mach Zehnder Modulator (MZM) that generates two m-QAM OFDM Single Sideband (SSB) signals based on phase shift of the hybrid coupler (90° and 120°). Our results show that the SSB signal with 120° hybrid coupler has suppresses the higher-order harmonics and makes the system more robust against the HD2 in the SMF-MMF optic link.

  4. Communication Links

    OpenAIRE

    2003-01-01

    This interactive tutorial helps learners to: Identify key upward, lateral, downward, and informal communication links in their organizations. , Reflect on the benefits, control, satisfaction, information filters, and feedback mechanism of various communication links in the organizations. OCL1000 Communicating Change in Complex Organizations

  5. Operative links

    DEFF Research Database (Denmark)

    Wistoft, Karen

    2010-01-01

    as networks: second, a semantic perspective on discourses and concepts of health, and, third, a health pedagogical perspective on participation, intervention, and roles. This paper argues for the importance of 'operative links' between different levels in health strategies. It is proposed that such links...

  6. TRAF7 Protein Promotes Lys-29-linked Polyubiquitination of IκB Kinase (IKKγ)/NF-κB Essential Modulator (NEMO) and p65/RelA Protein and Represses NF-κB Activation

    Science.gov (United States)

    Zotti, Tiziana; Uva, Antonio; Ferravante, Angela; Vessichelli, Mariangela; Scudiero, Ivan; Ceccarelli, Michele; Vito, Pasquale; Stilo, Romania

    2011-01-01

    Tumor necrosis factor receptor-associated factor (TRAF) proteins are cytoplasmic regulatory molecules that function as signal transducers for receptors involved in both innate and adaptive humoral immune responses. In this study, we show that TRAF7, the unique noncanonical member of the TRAF family, physically associates with IκB kinase/NF-κB essential modulator (NEMO) and with the RelA/p65 (p65) member of the NF-κB transcription factor family. TRAF7 promotes Lys-29-linked polyubiquitination of NEMO and p65 that results in lysosomal degradation of both proteins and altered activation. TRAF7 also influences p65 nuclear distribution. Microarray expression data are consistent with an inhibitory role for TRAF7 on NF-κB and a positive control of AP-1 transcription factor. Finally, functional data indicate that TRAF7 promotes cell death. Thus, this study identifies TRAF7 as a NEMO- and p65-interacting molecule and brings important information on the ubiquitination events that control NF-κB transcriptional activity. PMID:21518757

  7. TRAF7 protein promotes Lys-29-linked polyubiquitination of IkappaB kinase (IKKgamma)/NF-kappaB essential modulator (NEMO) and p65/RelA protein and represses NF-kappaB activation.

    Science.gov (United States)

    Zotti, Tiziana; Uva, Antonio; Ferravante, Angela; Vessichelli, Mariangela; Scudiero, Ivan; Ceccarelli, Michele; Vito, Pasquale; Stilo, Romania

    2011-07-01

    Tumor necrosis factor receptor-associated factor (TRAF) proteins are cytoplasmic regulatory molecules that function as signal transducers for receptors involved in both innate and adaptive humoral immune responses. In this study, we show that TRAF7, the unique noncanonical member of the TRAF family, physically associates with IκB kinase/NF-κB essential modulator (NEMO) and with the RelA/p65 (p65) member of the NF-κB transcription factor family. TRAF7 promotes Lys-29-linked polyubiquitination of NEMO and p65 that results in lysosomal degradation of both proteins and altered activation. TRAF7 also influences p65 nuclear distribution. Microarray expression data are consistent with an inhibitory role for TRAF7 on NF-κB and a positive control of AP-1 transcription factor. Finally, functional data indicate that TRAF7 promotes cell death. Thus, this study identifies TRAF7 as a NEMO- and p65-interacting molecule and brings important information on the ubiquitination events that control NF-κB transcriptional activity.

  8. Link module for a downhole drilling network

    Science.gov (United States)

    Hall, David R.; Fox, Joe

    2007-05-29

    A repeater is disclosed in one embodiment of the present invention as including a cylindrical housing, characterized by a proximal end and a distal end, and having a substantially cylindrical wall, the cylindrical wall defining a central bore passing therethrough. The cylindrical housing is formed to define at least one recess in the cylindrical wall, into which a repeater is inserted. The cylindrical housing also includes an annular recess formed into at least one of the proximal end and the distal end. An annular transmission element, operably connected to the repeater, is located in the annular recess. In selected embodiments, the annular transmission element inductively converts electrical energy to magnetic energy. In other embodiments, the annular transmission element includes an electrical contact to transmit electrical energy directly to another contact.

  9. Link Analysis

    Science.gov (United States)

    Donoho, Steve

    Link analysis is a collection of techniques that operate on data that can be represented as nodes and links. This chapter surveys a variety of techniques including subgraph matching, finding cliques and K-plexes, maximizing spread of influence, visualization, finding hubs and authorities, and combining with traditional techniques (classification, clustering, etc). It also surveys applications including social network analysis, viral marketing, Internet search, fraud detection, and crime prevention.

  10. The benefits of convergence.

    Science.gov (United States)

    Chang, Gee-Kung; Cheng, Lin

    2016-03-06

    A multi-tier radio access network (RAN) combining the strength of fibre-optic and radio access technologies employing adaptive microwave photonics interfaces and radio-over-fibre (RoF) techniques is envisioned for future heterogeneous wireless communications. All-band radio spectrum from 0.1 to 100 GHz will be used to deliver wireless services with high capacity, high link speed and low latency. The multi-tier RAN will improve the cell-edge performance in an integrated heterogeneous environment enabled by fibre-wireless integration and networking for mobile fronthaul/backhaul, resource sharing and all-layer centralization of multiple standards with different frequency bands and modulation formats. In essence, this is a 'no-more-cells' architecture in which carrier aggregation among multiple frequency bands can be easily achieved with seamless handover between cells. In this way, current and future mobile network standards such as 4G and 5G can coexist with optimized and continuous cell coverage using multi-tier RoF regardless of the underlying network topology or protocol. In terms of users' experience, the future-proof approach achieves the goals of system capacity, link speed, latency and continuous heterogeneous cell coverage while overcoming the bandwidth crunch in next-generation communication networks. © 2016 The Author(s).

  11. O-Linked N-Acetylglucosamine (O-GlcNAc) Expression Levels Epigenetically Regulate Colon Cancer Tumorigenesis by Affecting the Cancer Stem Cell Compartment via Modulating Expression of Transcriptional Factor MYBL1.

    Science.gov (United States)

    Guo, Huabei; Zhang, Bing; Nairn, Alison V; Nagy, Tamas; Moremen, Kelley W; Buckhaults, Phillip; Pierce, Michael

    2017-03-10

    To study the regulation of colorectal adenocarcinoma progression by O-GlcNAc, we have focused on the O-GlcNAc-mediated epigenetic regulation of human colon cancer stem cells (CCSC). Xenograft tumors from colon tumor cells with O-linked N-acetylglucosamine transferase (OGT) knockdown grew significantly slower than those formed from control cells, indicating a reduced proliferation of tumor cells due to inhibition of OGT expression. Significant reduction of the CCSC population was observed in the tumor cells after OGT knockdown, whereas tumor cells treated with the O-GlcNAcase inhibitor showed an increased CCSC population, indicating that O-GlcNAc levels regulated the CCSC compartment. When grown in suspension, tumor cells with OGT knockdown showed a reduced ability to form tumorspheres, indicating a reduced self-renewal of CCSC due to reduced levels of O-GlcNAc. ChIP-sequencing experiments using an anti-O-GlcNAc antibody revealed significant chromatin enrichment of O-GlcNAc-modified proteins at the promoter of the transcription factor MYBL1, which was also characterized by the presence of H3K27me3. RNA-sequencing analysis showed an increased expression of MYBL1 in tumor cells with OGT knockdown. Forced overexpression of MYBL1 led to a reduced population of CCSC and tumor growth in vivo, similar to the effects of OGT silencing. Moreover, two CpG islands near the transcription start site of MYBL1 were identified, and O-GlcNAc levels regulated their methylation status. These results strongly argue that O-GlcNAc epigenetically regulates MYBL1, functioning similarly to H3K27me3. The aberrant CCSC compartment observed after modulating O-GlcNAc levels is therefore likely to result, at least in part, from the epigenetic regulation of MYBL1 expression by O-GlcNAc, thereby significantly affecting tumor progression.

  12. On ω-Linked Overrings

    Institute of Scientific and Technical Information of China (English)

    Lin XIE; Fang Gui WANG; Yan TIAN

    2011-01-01

    Let R (C) T be an extension of commutative rings. T is called ω-linked over R if T as an R-module is a ω-module. In the case of R (C) T (C) Q0(R), T is called a ω-linked overring of R. As a generalization of Wang-McCsland-Park-Chang Theorem, we show that if R is a reduced ring, then R is a ω-Noetherian ring with ω-dim(R) ≤1 if and only if each ω-linked overring T of R is a ω-Noetherian ring with ω-dim(T) ≤ 1. In particular, R is a ω-Noetherian ring with ω-dim(R) = 0 if and only if R is an Artinian ring.

  13. New Optical Link Technologies for HEP Experiments

    CERN Document Server

    Delurgio, P; Salvachua, B; Lopez, D; Stanek, R; Underwood, D

    2011-01-01

    As a concern with the reliability and mass of current optical links in LHC experiments, we are investigating CW lasers and light modulators as an alternative to VCSELs. In addition we are developing data links in air, utilizing steering by MEMS mirrors and optical feedback paths for the control loop. Laser, modulator, and lens systems used are described, as well as two different electronic systems for a free space steering feedback loop. Our prototype system currently operates at 1.25 Gb/s, but could be upgraded. This link works over distances of order meters. Such links might enable one to move communication lasers (e.g. VCSELs) and optical fibers out of tracking detectors, for reasons such as reliability and power consumption. Some applications for free space data links, such as local triggering and data readout and trigger-clock distribution and links for much longer distances are also discussed.

  14. Transatlantic link

    Science.gov (United States)

    (left) European Geophysical Society (EGS) President Rolf Meissner at AGU Headquarters with (center) Executive Director Fred Spilhaus and (right) Foreign Secretary Juan Roederer. Meissner attended the meeting of AGU's Committee on International Participation (CIP) on February 26, 1988. At that meeting, specific ways of fostering close links between AGU and EGS were discussed.A few weeks later, Roederer and AGU staff, working with EGS Secretary-General Arne Richter at the EGS meeting in Bologna, Italy, March 21-25, planned details of the establishment of an AGU office in Europe. The Copernicus Gesellschaft, a new entity located on the premises of the Max Planck Institute for Aeronomy in Lindau, Federal Republic of Germany, will provide the administrative staff and handle logistics.

  15. -Regular Modules

    Directory of Open Access Journals (Sweden)

    Areej M. Abduldaim

    2013-01-01

    Full Text Available We introduced and studied -regular modules as a generalization of -regular rings to modules as well as regular modules (in the sense of Fieldhouse. An -module is called -regular if for each and , there exist and a positive integer such that . The notion of -pure submodules was introduced to generalize pure submodules and proved that an -module is -regular if and only if every submodule of is -pure iff   is a -regular -module for each maximal ideal of . Many characterizations and properties of -regular modules were given. An -module is -regular iff is a -regular ring for each iff is a -regular ring for finitely generated module . If is a -regular module, then .

  16. Dancing links

    CERN Document Server

    Knuth, Donald E

    2009-01-01

    The author presents two tricks to accelerate depth-first search algorithms for a class of combinatorial puzzle problems, such as tiling a tray by a fixed set of polyominoes. The first trick is to implement each assumption of the search with reversible local operations on doubly linked lists. By this trick, every step of the search affects the data incrementally. The second trick is to add a ghost square that represents the identity of each polyomino. Thus puts the rule that each polyomino be used once on the same footing as the rule that each square be covered once. The coding simplifies to a more abstract form which is equivalent to 0-1 integer programming. More significantly for the total computation time, the search can naturally switch between placing a fixed polyomino or covering a fixed square at different stages, according to a combined heuristic. Finally the author reports excellent performance for his algorithm for some familiar puzzles. These include tiling a hexagon by 19 hexiamonds and the N queen...

  17. Multi Tactical Data Link Information Cooperation Processing Module and Its Operating Method%多战术数据链信息协同处理模块及其运行方法

    Institute of Scientific and Technical Information of China (English)

    曾涛; 王雷; 巩克非

    2013-01-01

    Tactical data link has become a nerve which connects command center, all levels command post, fighting troops, weapons platforms and multi data terminals in the modern digital battlefield. Just one tactical data link is unable to meet all of campaign requirements, thus the situation that multi tactical data links occur together is formed. Multi tactical data link information cooperation processing shield differences between types of data link and physical transmission medium, real-time receive the data, monitor the communication status between aerial carrier and data links. The data of aerial carrier platform is downloaded to each data links in order to achieve the information cooperation processing of multi data link.%战术数据链已经成为现代数字化战场上链接指挥中心、各级指挥所、各参战部队和武器平台以及各种数据终端的神经,一种战术数据链不可能满足所有的作战需求,因此形成了这种多种战术数据链并存的局面。多战术数据链信息协同处理模块屏蔽不同类型数据链物理传输介质的差异,实时接收数据链数据、监测载机与各数据链的通讯状态、将载机平台数据下传至各数据链,实现多种数据链的数据信息协同处理。

  18. 100 Gb/s single VCSEL data transmission link

    DEFF Research Database (Denmark)

    Rodes Lopez, Roberto; Estaran Tolosa, Jose Manuel; Li, Bomin

    2012-01-01

    100 Gb/s optical fiber transmission link with a single 1.5 um VCSEL has been experimentally demonstrated using 4-level pulse amplitude modulation.......100 Gb/s optical fiber transmission link with a single 1.5 um VCSEL has been experimentally demonstrated using 4-level pulse amplitude modulation....

  19. The payload/shuttle-data-communication-link handbook

    Science.gov (United States)

    1982-01-01

    Communication links between the Orbiter, payloads, and ground are described: end-to-end, hardline, S-band, Ku-band, TDRSS relay, waveforms, premodulation, subcarrier modulation, carrier modulation, transmitter power, antennas, the RF channel, system noise, received signal-to-noise spectral density, carrier-tracking loop, carrier demodulation, subcarrier demodulation, digital data detection, digital data decoding, and tandem link considerations.

  20. Sex-linked dominant

    Science.gov (United States)

    Inheritance - sex-linked dominant; Genetics - sex-linked dominant; X-linked dominant; Y-linked dominant ... can be either an autosomal chromosome or a sex chromosome. It also depends on whether the trait ...

  1. Automatic modulation classification principles, algorithms and applications

    CERN Document Server

    Zhu, Zhechen

    2014-01-01

    Automatic Modulation Classification (AMC) has been a key technology in many military, security, and civilian telecommunication applications for decades. In military and security applications, modulation often serves as another level of encryption; in modern civilian applications, multiple modulation types can be employed by a signal transmitter to control the data rate and link reliability. This book offers comprehensive documentation of AMC models, algorithms and implementations for successful modulation recognition. It provides an invaluable theoretical and numerical comparison of AMC algo

  2. Multi-Functional Fibre-Optic Microwave Links

    DEFF Research Database (Denmark)

    Gliese, Ulrik Bo

    1998-01-01

    The multi-functionality of microwave links based on remote heterodyne detection of signals from a dual-frequency laser transmitter is discussed and experimentally demonstrated in this paper. Typically, direct detection in conjunction with optical intensity modulation is used to implement fibre......-optic microwave links. The resulting links are inherently transparent and mainly used for signal transmission. As opposed to direct detection links, remote heterodyne detection links can directly perform functionalities such as modulation, frequency conversion, and transparent signal recovery in addition...

  3. Ubiquitousness of link-density and link-pattern communities in real-world networks

    CERN Document Server

    Šubelj, Lovro

    2011-01-01

    Community structure appears to be an intrinsic property of many complex real-world networks. However, recent work shows that real-world networks reveal even more sophisticated modules than classical cohesive (link-density) communities. In particular, networks can also be naturally partitioned according to similar patterns of connectedness between the nodes, revealing link-pattern communities. We here propose a balanced propagation based algorithm that can extract both link-density and link-pattern communities, without any prior knowledge of the true structure. The algorithm was first validated on different classes of synthetic benchmark networks with community structure, and also on random networks. We have then further applied the algorithm to different social, information, technological and biological networks, where it indeed reveals meaningful (composites of) link-density and link-pattern communities. The results thus seem to imply that, similarly as link-density counterparts, link-pattern communities app...

  4. Photovoltaic module mounting system

    Science.gov (United States)

    Miros, Robert H. J.; Mittan, Margaret Birmingham; Seery, Martin N.; Holland, Rodney H.

    2012-04-17

    A solar array mounting system having unique installation, load distribution, and grounding features, and which is adaptable for mounting solar panels having no external frame. The solar array mounting system includes flexible, pedestal-style feet and structural links connected in a grid formation on the mounting surface. The photovoltaic modules are secured in place via the use of attachment clamps that grip the edge of the typically glass substrate. The panel mounting clamps are then held in place by tilt brackets and/or mid-link brackets that provide fixation for the clamps and align the solar panels at a tilt to the horizontal mounting surface. The tilt brackets are held in place atop the flexible feet and connected link members thus creating a complete mounting structure.

  5. Linked alternating forms and linked symplectic Grassmannians

    CERN Document Server

    Osserman, Brian

    2011-01-01

    Motivated by applications to higher-rank Brill-Noether theory and the Bertram-Feinberg-Mukai conjecture, we introduce the concepts of linked alternating and linked symplectic forms on a chain of vector bundles, and show that the linked symplectic Grassmannians parametrizing chains of subbundles isotropic for a given linked symplectic form has good dimensional behavior analogous to that of the classical symplectic Grassmannian.

  6. Towards convergence of wireless and wireline signal transport in broadband access networks

    DEFF Research Database (Denmark)

    Yu, Xianbin; Prince, Kamau; Tafur Monroy, Idelfonso

    2010-01-01

    Hybrid optical wireless access networks are to play an important role in the realization of the vision of delivery of broadband services to the end-user any time, anywhere and at affordable costs. We present results of experiments conducted over a field deployed optical fibre links we successfull...... demonstrated converged wireless and wireline signal transport over a common fibre infrastructure. The type of signal used in this field deployed experiments cover WiMax, Impulse-radio ultra-wideband (UWB) and coherent transmission of baseband QPSK and radio-over-fibre signals....

  7. Based on the MZI phase modulation of light load wireless down-conversion link research%基于MZI相位调制的光载无线下变频链路研究

    Institute of Scientific and Technical Information of China (English)

    谭宝明

    2012-01-01

      This article analyze and experimentally demonstrate a technique for transmitting microwave signals over an optical fiber and down-converting them to an intermediate frequency at the receiver. The system uses two phase modulators to optically heterodyne the microwave input signal with a microwave local oscillator. The phase modulated signal is detected at the receiver using an optical delay-line interferometer and a pair of balanced photo-dectectors. This simple configuration allows down-conversion with relatively high gain.%  论文分析并实验验证了一种使用光纤传输微波信号的技术,并且在接收端把射频信号转换为中频信号。该系统使用两个相位调制器,一个位于发射端,一个位于接收端,在光域外差输入的微波信号和微波本振。相位调制信号在接收端通过一个光延时线干涉仪进行解调,并用一对平衡探测器进行探测。该结构可以同时实现频率下变换和共模噪声的抑制,并且具有较高的频率下变换增益。

  8. The Gigabit Link Interface Board (GLIB) ecosystem

    CERN Document Server

    Vichoudis, P; Baron, S; Barros Marin, M; Bobillier, V; Chramowitz, J; Haas, S; Hansen, M; Joos, M; Lobato Pardavila, L; Petit, P; Prosser, A; Vasey, F

    2013-01-01

    The Gigabit Link Interface Board (GLIB) project is an FPGA-based platform for users of high-speed optical links in high energy physics experiments. The major hardware component of the platform is the GLIB Advanced Mezzanine Card (AMC). Additionally to the AMC, auxiliary components are developed that enhance GLIB platform's I/O bandwidth and compatibility with legacy and future triggering and/or data acquisition interfaces. This article focuses on the development of the auxiliary components that together with the GLIB AMC offer a complete solution for beam/irradiation tests of detector modules and evaluation of optical links.

  9. The Versatile Link Demo Board (VLDB)

    Science.gov (United States)

    Martín Lesma, R.; Alessio, F.; Barbosa, J.; Baron, S.; Caplan, C.; Leitao, P.; Pecoraro, C.; Porret, D.; Wyllie, K.

    2017-02-01

    The Versatile Link Demonstrator Board (VLDB) is the evaluation kit for the radiation-hard Optical Link ecosystem, which provides a 4.8 Gbps data transfer link for communication between front-end (FE) and back-end (BE) of the High Energy Physics experiments. It gathers the Versatile link main radiation-hard custom Application-Specific Integrated Circuits (ASICs) and modules: GBTx, GBT-SCA and VTRx/VTTx plus the FeastMP, a radiation-hard in-house designed DC-DC converter. This board is the first design allowing system-level tests of the Link with a complete interconnection of the constitutive components, allowing data acquisition, control and monitoring of FE devices with the GBT-SCA pair.

  10. Linked data management

    CERN Document Server

    Hose, Katja; Schenkel, Ralf

    2014-01-01

    Linked Data Management presents techniques for querying and managing Linked Data that is available on today’s Web. The book shows how the abundance of Linked Data can serve as fertile ground for research and commercial applications. The text focuses on aspects of managing large-scale collections of Linked Data. It offers a detailed introduction to Linked Data and related standards, including the main principles distinguishing Linked Data from standard database technology. Chapters also describe how to generate links between datasets and explain the overall architecture of data integration systems based on Linked Data. A large part of the text is devoted to query processing in different setups. After presenting methods to publish relational data as Linked Data and efficient centralized processing, the book explores lookup-based, distributed, and parallel solutions. It then addresses advanced topics, such as reasoning, and discusses work related to read-write Linked Data for system interoperation. Desp...

  11. Silicon Optical Modulator Simulation

    Directory of Open Access Journals (Sweden)

    Soon Thor LIM

    2015-04-01

    Full Text Available We developed a way of predicting and analyzing high speed optical modulator. Our research adopted a bottom-up approach to consider high-speed optical links using an eye diagram. Our method leverages on modular mapping of electrical characteristics to optical characteristics, while attaining the required accuracy necessary for device footprint approaching sub-micron scales where electrical data distribution varies drastically. We calculate for the bias dependent phase shift (2pi/mm and loss (dB/mm for the optical modulator based on the real and imaginary part of complex effective indices. Subsequently, combine effectively both the electrical and optical profiles to construct the optical eye diagram which is the essential gist of signal integrity of such devices.

  12. Novel Link Adaptation Schemes for OFDM System

    Institute of Scientific and Technical Information of China (English)

    LEI Ming; CAI Peng; XU Yue-shan; ZHANG Ping

    2003-01-01

    Orthogonal Frequency Division Multiplexing (OFDM) is the most promising technique supporting the high data rate transmission. The combination of the link adaptation and OFDM can further increase the spectral efficiency. In this paper, we put forward two link adaptation schemes for OFDM system which have the advantages of both flexibility and practicability. Both of the two novel link adaptation schemes are based on the iterative mechanism to allocate the bit and power to subcarriers according to their channel gains and noisy levels which are assumed to be already known at the transmitter. The candidate modulation modes are determined freely before the link adaptation schemes are performed. The distinction between the two novel link adaptation schemes is that in the novel scheme A, the modulation mode is upgraded to the neighboring higher-order mode, while in the novel scheme B the modulation is upgraded to the genuine optimal mode. Therefore, the novel scheme A has the advantage of lower complexity and the novel scheme B has the advantage of higher spectral efficiency.

  13. Equipment selection heuristics for microwave fixed links

    Science.gov (United States)

    Flood, I. D.; Allen, S. M.

    2014-08-01

    Microwave fixed links use highly standardized radio equipment and, in the radio equipment standard referenced in this paper, there is a choice between exactly two radio systems when the assigner wishes to resolve a specific data rate exactly: one using a relatively lower-order modulation scheme and one a relatively higher-order scheme. Although the higher-order equipment requires less bandwidth for an isolated link, these systems radiate at higher powers and require larger protection ratios in the radio interference environment which lead to well-established trade-offs between modulation, bandwidth, equivalent isotropic radiated power, and frequency assignment criteria. Our earlier research showed that by extending the Frequency Assignment Problem to include equipment selection and using lower-order modulation equipment on selected links, we can actually reduce the overall span of frequencies required for a network frequency assignment. This work focused on the development of integer programming formulations and analyzed the exact solutions obtained. Exact solutions are impractical for real world problems; hence, here we focus on the development of heuristics for equipment selection. We can model the fixed link network as a complete graph where the vertices represent fixed link frequency assignment requests and the edges represent interference between pairs of vertices. Using a graph theoretic analysis of the interference problem, we propose heuristic techniques and discuss the relative success of our approach in this article.

  14. Irreducible Specht modules are signed Young modules

    OpenAIRE

    Hemmer, David J.

    2005-01-01

    Recently Donkin defined signed Young modules as a simultaneous generalization of Young and twisted Young modules for the symmetric group. We show that in odd characteristic, if a Specht module $S^\\lambda$ is irreducible, then $S^\\lambda$ is a signed Young module. Thus the set of irreducible Specht modules coincides with the set of irreducible signed Young modules. This provides evidence for our conjecture that the signed Young modules are precisely the class of indecomposable self-dual module...

  15. Function of Integrin-Linked Kinase in Modulating the Stemness of IL-6–Abundant Breast Cancer Cells by Regulating γ-Secretase–Mediated Notch1 Activation in Caveolae

    Directory of Open Access Journals (Sweden)

    En-Chi Hsu

    2015-06-01

    Full Text Available Interleukin-6 (IL-6 and Notch signaling are important regulators of breast cancer stem cells (CSCs, which drive the malignant phenotype through self-renewal, differentiation, and development of therapeutic resistance. We investigated the role of integrin-linked kinase (ILK in regulating IL-6–driven Notch1 activation and the ability to target breast CSCs through ILK inhibition. Ectopic expression/short hairpin RNA-mediated knockdown of ILK, pharmacological inhibition of ILK with the small molecule T315, Western blot analysis, immunofluorescence, and luciferase reporter assays were used to evaluate the regulation of IL-6–driven Notch1 activation by ILK in IL-6–producing triple-negative breast cancer cell lines (MDA-MB-231, SUM-159 and in MCF-7 and MCF-7IL-6 cells. The effects of ILK on γ-secretase complex assembly and cellular localization were determined by immunofluorescence, Western blots of membrane fractions, and immunoprecipitation. In vivo effects of T315-induced ILK inhibition on CSCs in SUM-159 xenograft models were assessed by mammosphere assays, flow cytometry, and tumorigenicity assays. Results show that the genetic knockdown or pharmacological inhibition of ILK suppressed Notch1 activation and the abundance of the γ-secretase components presenilin-1, nicastrin, and presenilin enhancer 2 at the posttranscriptional level via inhibition of caveolin-1-dependent membrane assembly of the γ-secretase complex. Accordingly, knockdown of ILK inhibited breast CSC-like properties in vitro and the breast CSC subpopulation in vivo in xenograft tumor models. Based on these findings, we propose a novel function of ILK in regulating γ-secretase–mediated Notch1 activation, which suggests the targeting of ILK as a therapeutic approach to suppress IL-6–induced breast CSCs.

  16. *-Modules, co-*-modules and cotilting modules over Noetherian rings

    Institute of Scientific and Technical Information of China (English)

    汪明义; 许永华

    1996-01-01

    Let R be a Noetherian ring. The projectivity and injectivity of modules over R are discussed. The concept of modules is introduced and the descriptions for co-*-modules over R are given. At last, cotilting modules over R are characterized by means of co-*-modules.

  17. Thruster Module

    Science.gov (United States)

    Andersson, G.

    2015-09-01

    The thruster module described in this paper provides a low but controlled acceleration in a mission which would normally be labelled “microgravity”. The first mission was Cryofenix, where tanks containing liquid hydrogen were used in the experiment. The experiment utilizing the low acceleration is using liquids and requires a precise acceleration profile throughout the mission. Acceleration obtained by payload rotation is not feasible due to that the transversal forces required to change the acceleration will cause undesired liquid turbulence. In order to satisfy the experiment requirements a thruster module was developed by SSC for the Cryofenix mission funded by CNES. The Cryofenix mission had a payload weight of 380 kg and an apogee of about 260 km. The module produces a controlled thrust in flight direction by means of a cold gas system.

  18. FPGA based fast synchronous serial multi-wire links synchronization

    Science.gov (United States)

    Pozniak, Krzysztof T.

    2013-10-01

    The paper debates synchronization method of multi-wire, serial link of constant latency, by means of pseudo-random numbers generators. The solution was designed for various families of FPGA circuits. There were debated synchronization algorithm and functional structure of parameterized transmitter and receiver modules. The modules were realized in VHDL language in a behavioral form.

  19. Signed Young Modules and Simple Specht Modules

    OpenAIRE

    Danz, Susanne; Lim, Kay Jin

    2015-01-01

    By a result of Hemmer, every simple Specht module of a finite symmetric group over a field of odd characteristic is a signed Young module. While Specht modules are parametrized by partitions, indecomposable signed Young modules are parametrized by certain pairs of partitions. The main result of this article establishes the signed Young module labels of simple Specht modules. Along the way we prove a number of results concerning indecomposable signed Young modules that are of independent inter...

  20. Weierstrass polynomials for links

    DEFF Research Database (Denmark)

    Hansen, Vagn Lundsgaard

    1997-01-01

    There is a natural way of identifying links in3-space with polynomial covering spaces over thecircle. Thereby any link in 3-space can be definedby a Weierstrass polynomial over the circle. Theequivalence relation for covering spaces over thecircle is, however, completely different from...... that for links in 3-space. This paper initiates a study of the connections between polynomial covering spaces over the circle and links in 3-space....

  1. Memory Modulation

    NARCIS (Netherlands)

    Roozendaal, Benno; McGaugh, James L.

    2011-01-01

    Our memories are not all created equally strong: Some experiences are well remembered while others are remembered poorly, if at all. Research on memory modulation investigates the neurobiological processes and systems that contribute to such differences in the strength of our memories. Extensive evi

  2. Analyzing the Low Power Wireless Links for Wireless Sensor Networks

    CERN Document Server

    Mamun, Md Mainul Islam; Kumar, Sumon; Islam, Md Zahidul

    2010-01-01

    There is now an increased understanding of the need for realistic link layer models in the wireless sensor networks. In this paper, we have used mathematical techniques from communication theory to model and analyze low power wireless links. Our work provides theoretical models for the link layer showing how Packet Reception Rate vary with Signal to Noise Ratio and distance for different modulation schemes and a comparison between MICA2 and TinyNode in terms of PRR.

  3. Module Evaluation

    Science.gov (United States)

    2006-02-01

    MODULES IN LIFE TEST CHAMBER (LEFT SIDE) 68 MODULE TRANSMIT TEMP CA1 54.8°C CB1 65.3°C CC1 70.5°C CD1 75.2°C CE1 68.5°C CA2 72.1°C CB2 ...NO. PA (Contractor) PA (MELTS) DRV (Contractor) DRV (MELTS) CA1 058 +11.0 VOLTS +10.3 VOLTS + 7.5 VOLTS + 3.64 VOLTS CB1 085 +11.0 VOLTS +10.13...CE1 032 +11.0 VOLTS + 7.02 VOLTS + 7.5 VOLTS + 4.23 VOLTS CA2 065 +11.0 VOLTS +11.03 VOLTS + 7.5 VOLTS + 7.53 VOLTS CB2 057 +11.0 VOLTS + 9.49

  4. Module descriptor

    DEFF Research Database (Denmark)

    Vincenti, Gordon; Klausen, Bodil; Kjær Jensen, Jesper

    2016-01-01

    The Module Descriptor including a Teacher’s Guide explains and describes how to work innovatively and co-creatively with wicked problems and young people. The descriptor shows how interested educators and lecturers in Europe can copy the lessons of the Erasmus+ project HIP when teaching their own...... students how to include marginalized young people and practitioners in the education of future social workers and social educators....

  5. Module descriptor

    DEFF Research Database (Denmark)

    Vincenti, Gordon; Klausen, Bodil; Kjær Jensen, Jesper

    2016-01-01

    The Module Descriptor including a Teacher’s Guide explains and describes how to work innovatively and co-creatively with wicked problems and young people. The descriptor shows how interested educators and lecturers in Europe can copy the lessons of the Erasmus+ project HIP when teaching their own...... students how to include marginalized young people and practitioners in the education of future social workers and social educators....

  6. Photovoltaic module and module arrays

    Science.gov (United States)

    Botkin, Jonathan; Graves, Simon; Lenox, Carl J. S.; Culligan, Matthew; Danning, Matt

    2012-07-17

    A photovoltaic (PV) module including a PV device and a frame. The PV device has a PV laminate defining a perimeter and a major plane. The frame is assembled to and encases the laminate perimeter, and includes leading, trailing, and side frame members, and an arm that forms a support face opposite the laminate. The support face is adapted for placement against a horizontal installation surface, to support and orient the laminate in a non-parallel or tilted arrangement. Upon final assembly, the laminate and the frame combine to define a unitary structure. The frame can orient the laminate at an angle in the range of 3.degree.-7.degree. from horizontal, and can be entirely formed of a polymeric material. Optionally, the arm incorporates integral feature(s) that facilitate interconnection with corresponding features of a second, identically formed PV module.

  7. Linking open vocabularies

    CERN Document Server

    Greifender, Elke; Seadle, Michael

    2013-01-01

    Linked Data (LD), Linked Open Data (LOD) and generating a web of data, present the new knowledge sharing frontier. In a philosophical context, LD is an evolving environment that reflects humankinds' desire to understand the world by drawing on the latest technologies and capabilities of the time. LD, while seemingly a new phenomenon did not emerge overnight; rather it represents the natural progression by which knowledge structures are developed, used, and shared. Linked Open Vocabularies is a significant trajectory of LD. Linked Open Vocabularies targets vocabularies that have traditionally b

  8. Identifying Functional Modules in Complex Networks

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    In this paper, we propose a new method that enables us to detect and describe the functional modules in complex networks. Using the proposed method, we can classify the nodes of networks into different modules according to their pattern of intra- and extra-module links. We use our method to analyze the modular structures of the ER random networks. We find that different modules of networks have different structure properties, such as the clustering coefficient. Moreover, at the same time, many nodes of networks participate different modules. Remarkably, we find that in the ER random networks, when the probability p is small, different modules or different roles of nodes can be identified by different regionsin the c-p parameter space.

  9. Let's "Downscale" Linked Data

    NARCIS (Netherlands)

    Gueret, Christophe; de Boer, Victor; Schlobach, Stefan

    2014-01-01

    Open data policies and linked data publication are powerful tools for increasing transparency, participatory governance, and accountability. A closer look at linked data technologies, however, proves that their design and deployment exclude the majority of the world’s population. It will take small

  10. Typed links in Webvise

    DEFF Research Database (Denmark)

    1999-01-01

    We extended the Webvise open hypermedia system with support for typed links.  The ECDL'99 paper describes these extensions.......We extended the Webvise open hypermedia system with support for typed links.  The ECDL'99 paper describes these extensions....

  11. Il progetto Linked Heritage

    Directory of Open Access Journals (Sweden)

    Marzia Piccininno

    2013-03-01

    Full Text Available ItLinked Heritage è uno dei progetti di punta finanziati dalla Commissione europea per alimentare Europeana, il portale dei contenuti culturali digitali europei. Linked Heritage raccoglie, sotto il coordinamento dell’ICCU, un consorzio molto vasto i cui partner provengono da quasi tutti i paesi dell’Unione più Russia e Israele; essi forniranno a Europeana ben 3 milioni di risorse digitali. Oltre al tema dell’aggregazione di contenuti culturali digitali, Linked Heritage sta esplorando altri temi fondamentali per Europeana come il multilinguismo, i linked data e il rapporto con possibili partner commerciali. Linked Heritage è l’ultimo in ordine di tempo di una serie di iniziative progettuali avviate da un consorzio europeo di istituzioni che opera insieme da oltre dieci anni nell’ambito del patrimonio culturale digitale.EnLinked Heritage is one of the flagship projects funded by the European commission to feed Europeana, the portal of the European digital cultural content. Linked Heritage has a very large partnership, coordinated by ICCU, whose members come from many European countries, Russia and Israel; they will supply Europeana with 3 million digital resources. Beyond the aggregation of digital cultural content, Linked Heritage is exploring other topics which are essential for Europeana, like multilingualism, linked data and the relationship with the commercial partners. Linked Heritage is the last one in time of a series of projects made up by a European consortium of institutions that has been working for over ten years in the field of digital cultural heritage.

  12. Highly Sensitive Electro-Optic Modulators

    Energy Technology Data Exchange (ETDEWEB)

    DeVore, Peter S [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2015-10-26

    There are very important diagnostic and communication applications that receive faint electrical signals to be transmitted over long distances for capture. Optical links reduce bandwidth and distance restrictions of metal transmission lines; however, such signals are only weakly imprinted onto the optical carrier, resulting in low fidelity transmission. Increasing signal fidelity often necessitates insertion of radio-frequency (RF) amplifiers before the electro-optic modulator, but (especially at high frequencies) RF amplification results in large irreversible distortions. We have investigated the feasibility of a Sensitive and Linear Modulation by Optical Nonlinearity (SALMON) modulator to supersede RF-amplified modulators. SALMON uses cross-phase modulation, a manifestation of the Kerr effect, to enhance the modulation depth of an RF-modulated optical wave. This ultrafast process has the potential to result in less irreversible distortions as compared to a RF-amplified modulator due to the broadband nature of the Kerr effect. Here, we prove that a SALMON modulator is a feasible alternative to an RFamplified modulator, by demonstrating a sensitivity enhancement factor greater than 20 and significantly reduced distortion.

  13. MEMORY MODULATION

    Science.gov (United States)

    Roozendaal, Benno; McGaugh, James L.

    2011-01-01

    Our memories are not all created equally strong: Some experiences are well remembered while others are remembered poorly, if at all. Research on memory modulation investigates the neurobiological processes and systems that contribute to such differences in the strength of our memories. Extensive evidence from both animal and human research indicates that emotionally significant experiences activate hormonal and brain systems that regulate the consolidation of newly acquired memories. These effects are integrated through noradrenergic activation of the basolateral amygdala which regulates memory consolidation via interactions with many other brain regions involved in consolidating memories of recent experiences. Modulatory systems not only influence neurobiological processes underlying the consolidation of new information, but also affect other mnemonic processes, including memory extinction, memory recall and working memory. In contrast to their enhancing effects on consolidation, adrenal stress hormones impair memory retrieval and working memory. Such effects, as with memory consolidation, require noradrenergic activation of the basolateral amygdala and interactions with other brain regions. PMID:22122145

  14. Challenges and Capacity Analysis of 100 Gbps Optical Fibre Wireless Links in 75-110 GHz Band

    DEFF Research Database (Denmark)

    Dogadaev, Anton Konstantinovich; Tafur Monroy, Idelfonso

    2011-01-01

    We report on the capacity analysis of hybrid optical fiber-wireless links operating at 75-110 GHz band. We provide link design guidelines towards achieving 100 Gbps data transmission using M-ary modulation formats.......We report on the capacity analysis of hybrid optical fiber-wireless links operating at 75-110 GHz band. We provide link design guidelines towards achieving 100 Gbps data transmission using M-ary modulation formats....

  15. Module 6

    DEFF Research Database (Denmark)

    Wilson, Douglas Clyde

    2013-01-01

    Reconciliation Action Plans are political instruments that are implemented in political contexts. Getting a good grasp of who the relevant stakeholders are is critical to their effectiveness. A discourse analysis is a method for identifying stakeholders, understanding where they are in conflict......, and identifying potential compromises among them. It investigates how facts, values and interests are linked together into coherent themes. These themes are drawn upon in various ways by different stakeholder groups as they express their understandings of the issues that the RAP must address. A discourse analysis...... always begins with in-depth qualitative interviews with stakeholders through which the themes are initially identified. Several more advanced methods are available, including quantitative ones that can be used to understand more complex discourses....

  16. Dynamical fat link fermions

    CERN Document Server

    Kamleh, W; Williams, A G; Kamleh, Waseem; Leinweber, Derek B.; Williams, Anthony G.; 10.1016/j.nuclphysbps.2003.12.058

    2004-01-01

    The use of APE smearing or other blocking techniques in fermion actions can provide many advantages. There are many variants of these fat link actions in lattice QCD currently, such as FLIC fermions. Frequently, fat link actions make use of the APE blocking technique in combination with a projection of the blocked links back into the special unitary group. This reunitarisation is often performed using an iterative maximisation of a gauge invariant measure. This technique is not differentiable with respect to the gauge field and thus prevents the use of standard Hybrid Monte Carlo simulation algorithms. The use of an alternative projection technique circumvents this difficulty and allows the simulation of dynamical fat link fermions with standard HMC and its variants.

  17. Link to paper

    Data.gov (United States)

    U.S. Environmental Protection Agency — Link to the paper. This dataset is associated with the following publication: Naile, J., A.W. Garrison, J. Avants, and J. Washington. Isomers/enantiomers of...

  18. Latest Research: Genetic Links

    Science.gov (United States)

    ... Current Issue Past Issues Feature: Vision Latest Research: Genetic Links Past Issues / Summer 2008 Table of Contents ... inside the eye is a risk factor for glaucoma. Summer 2008 Issue: Volume 3 Number 3 Page ...

  19. Linked Ocean Data

    Science.gov (United States)

    Leadbetter, Adam; Arko, Robert; Chandler, Cynthia; Shepherd, Adam

    2014-05-01

    "Linked Data" is a term used in Computer Science to encapsulate a methodology for publishing data and metadata in a structured format so that links may be created and exploited between objects. Berners-Lee (2006) outlines the following four design principles of a Linked Data system: Use Uniform Resource Identifiers (URIs) as names for things. Use HyperText Transfer Protocol (HTTP) URIs so that people can look up those names. When someone looks up a URI, provide useful information, using the standards (Resource Description Framework [RDF] and the RDF query language [SPARQL]). Include links to other URIs so that they can discover more things. In 2010, Berners-Lee revisited his original design plan for Linked Data to encourage data owners along a path to "good Linked Data". This revision involved the creation of a five star rating system for Linked Data outlined below. One star: Available on the web (in any format). Two stars: Available as machine-readable structured data (e.g. An Excel spreadsheet instead of an image scan of a table). Three stars: As two stars plus the use of a non-proprietary format (e.g. Comma Separated Values instead of Excel). Four stars: As three stars plus the use of open standards from the World Wide Web Commission (W3C) (i.e. RDF and SPARQL) to identify things, so that people can point to your data and metadata. Five stars: All the above plus link your data to other people's data to provide context Here we present work building on the SeaDataNet common vocabularies served by the NERC Vocabulary Server, connecting projects such as the Rolling Deck to Repository (R2R) and the Biological and Chemical Oceanography Data Management Office (BCO-DMO) and other vocabularies such as the Marine Metadata Interoperability Ontology Register and Repository and the NASA Global Change Master Directory to create a Linked Ocean Data cloud. Publishing the vocabularies and metadata in standard RDF XML and exposing SPARQL endpoints renders them five-star Linked

  20. Interference susceptibility measurements for an MSK satellite communication link

    Science.gov (United States)

    Kerczewski, Robert J.; Fujikawa, Gene

    1992-01-01

    The results are presented of measurements of the degradation of an MSK satellite link due to modulated and CW (unmodulated) interference. These measurements were made using a hardware based satellite communication link simulator at NASA-Lewis. The results indicate the amount of bit error rate degradation caused by CW interference as a function of frequency and power level, and the degradation caused by adjacent channel and cochannel modulated interference as a function of interference power level. Results were obtained for both the uplink case (including satellite nonlinearity) and the downlink case (linear channel).

  1. Module theory, extending modules and generalizations

    CERN Document Server

    Tercan, Adnan

    2016-01-01

    The main focus of this monograph is to offer a comprehensive presentation of known and new results on various generalizations of CS-modules and CS-rings. Extending (or CS) modules are generalizations of injective (and also semisimple or uniform) modules. While the theory of CS-modules is well documented in monographs and textbooks, results on generalized forms of the CS property as well as dual notions are far less present in the literature. With their work the authors provide a solid background to module theory, accessible to anyone familiar with basic abstract algebra. The focus of the book is on direct sums of CS-modules and classes of modules related to CS-modules, such as relative (injective) ejective modules, (quasi) continuous modules, and lifting modules. In particular, matrix CS-rings are studied and clear proofs of fundamental decomposition results on CS-modules over commutative domains are given, thus complementing existing monographs in this area. Open problems round out the work and establish the...

  2. Cofinitely weak supplemented modules

    OpenAIRE

    Alizade, Rafail; Büyükaşık, Engin

    2003-01-01

    We prove that a module M is cofinitely weak supplemented or briefly cws (i.e., every submodule N of M with M/N finitely generated, has a weak supplement) if and only if every maximal submodule has a weak supplement. If M is a cws-module then every M-generated module is a cws-module. Every module is cws if and only if the ring is semilocal. We study also modules, whose finitely generated submodules have weak supplements.

  3. On generalized extending modules

    Institute of Scientific and Technical Information of China (English)

    ZENG Qing-yi

    2007-01-01

    A module M is called generalized extending if for any submodule N of M, there is a direct summand K of M such that N≤K and K/N is singular. Any extending module and any singular module are generalized extending. Any homomorphic image of a generalized extending module is generalized extending. Any direct sum of a singular (uniform) module and a semi-simple module is generalized extending. A ring R is a right Co-H-ring ifand only ifall right R modules are generalized extending modules.

  4. All-Optical Photochromic Spatial Light Modulators

    Science.gov (United States)

    Beratan, David N.; Perry, Joseph W.

    1989-01-01

    Photochemical transfer of electrons enables fast reading and writing. New concept based on transfer of electrons between donor and acceptor molecules randomly distributed or covalently linked and dispersed in glassy-polymer host material. Transfer causes significant changes in optical-transmission characteristics of material and used to modulate transmission of reading beam of light impinging on material.

  5. Wireline equalization using pulse-width modulation

    NARCIS (Netherlands)

    Schrader, J.H.R.; Klumperink, Eric A.M.; Visschers, J.L.; Nauta, Bram

    2006-01-01

    Abstract-High-speed data links over copper cables can be effectively equalized using pulse-width modulation (PWM) pre-emphasis. This provides an alternative to the usual 2-tap FIR filters. The use of PWM pre-emphasis allows a channel loss at the Nyquist frequency of ~30dB, compared to ~20dB for a

  6. Performance analysis of the ultra-linear optical intensity modulator

    Science.gov (United States)

    Madamopoulos, Nicholas; Dingel, Benjamin

    2006-10-01

    The linear optical intensity modulator is a key component in any broadband optical access-based analog fiber-optic link systems such as sub-carrier multiplexing (SCM) systems, ultra-dense CATV, Radio-over-Fiber (RoF) communications, and other platform access systems. Previously, we have proposed a super-linear optical modulator, having SFDR = 130 -140 dB-Hz 2/3, based on a unique combination of phase-modulator (PM) and a weak ring resonator (RR) modulator within a Mach-Zehnder interferometer (MZI). We presented some of its unique features. In this paper, we characterize further this ultra-linear optical intensity modulator, analyze its RF performance and provide method for parameter optimization. Other excellent features of this modulator design such as high manufacturing tolerance, effect of link insertion loss, adaptive characteristic and device simplicity are also discussed.

  7. Design and fabrication of traveling wave electroabsorption modulator

    Science.gov (United States)

    Li, Guoliang; Shin, Dong-Soo; Chang, William S. C.; Asbeck, Peter M.; Yu, Paul K. L.; Sun, Chen K.; Pappert, Stephen A.; Nguyen, Richard

    2000-04-01

    Semiconductor electroabsorption modulator (EAM) is a promising alternative to lithium niobate modulator for digital and analog fiber optic links due to its inherent small size, high modulation efficiency, and potential of monolithic integration with other electronic and optoelectronic components. For high-speed application, the bandwidth of the lumped element EAM is known to be RC-time limited. To achieve an ultra large bandwidth in lumped element EAM, the modulation efficiency has to be greatly sacrificed. This is especially critical in analog operation where RF link loss and noise figure must be minimized. To overcome the RC bandwidth limit and to avoid significantly compromising the modulation efficiency, the traveling wave electroabsorption modulator has been proposed and experimentally investigated by several authors.

  8. Ballasted photovoltaic module and module arrays

    Science.gov (United States)

    Botkin, Jonathan; Graves, Simon; Danning, Matt

    2011-11-29

    A photovoltaic (PV) module assembly including a PV module and a ballast tray. The PV module includes a PV device and a frame. A PV laminate is assembled to the frame, and the frame includes an arm. The ballast tray is adapted for containing ballast and is removably associated with the PV module in a ballasting state where the tray is vertically under the PV laminate and vertically over the arm to impede overt displacement of the PV module. The PV module assembly can be installed to a flat commercial rooftop, with the PV module and the ballast tray both resting upon the rooftop. In some embodiments, the ballasting state includes corresponding surfaces of the arm and the tray being spaced from one another under normal (low or no wind) conditions, such that the frame is not continuously subjected to a weight of the tray.

  9. High Capacity Radio over Fiber Transmission Links

    DEFF Research Database (Denmark)

    Caballero Jambrina, Antonio

    . This achievement has satisfied the requirements on transmission robustness and high capacity of next generation hybrid optical fibre-wireless networks. One important contribution of this thesis is the novel concept of photonic downconversion with free-running pulsed laser source for phase modulated Radio...... confirmed that this configuration provides high linear end-to-end transmission links and is capable of transparent transport of high spectral efficient modulation formats. Furthermore, this thesis introduces a novel approach for the generation and detection of high speed wireless signals in mm...... of the writing of this thesis. In conclusion, the results presented in this thesis demonstrate the feasibility of photonic technologies for the generation, distribution and detection of high speed wireless signals. Furthermore, it opens the prospects for next generation hybrid wireless-wired access networks...

  10. Links, Exchanges, Sharing.

    Science.gov (United States)

    Shearer, James

    1992-01-01

    Describes the international activities of the Thames Valley University's Department of Information Management, including formal academic links with overseas institutions, development of short courses for practitioners, discussion meetings, staff and student visits, and enrollment of international students. Topics addressed include personnel,…

  11. Response model parameter linking

    NARCIS (Netherlands)

    Barrett, Michelle Derbenwick

    2015-01-01

    With a few exceptions, the problem of linking item response model parameters from different item calibrations has been conceptualized as an instance of the problem of equating observed scores on different test forms. This thesis argues, however, that the use of item response models does not require

  12. Linking Literacy and Movement

    Science.gov (United States)

    Pica, Rae

    2010-01-01

    There are many links between literacy and movement. Movement and language are both forms of communication and self-expression. Rhythm is an essential component of both language and movement. While people may think of rhythm primarily in musical terms, there is a rhythm to words and sentences as well. Individuals develop an internal rhythm when…

  13. Linking place and mind

    DEFF Research Database (Denmark)

    Jensen, Marie Møller

    2016-01-01

    This paper investigates the salience of vernacular Tyneside forms on the basis of theories of enregisterment and exemplar processing. On one level, exemplar theory provides a psycholinguistic account of how the link between social value and linguistic features is possible. Conversely, integrating...

  14. Link Influence Entropy

    Science.gov (United States)

    Singh, Priti; Chakraborty, Abhishek; Manoj, B. S.

    2017-01-01

    In this paper we propose a new metric, Link Influence Entropy (LInE), which describes importance of each node based on the influence of each link present in a network. Influence of a link can neither be effectively estimated using betweenness centrality nor using degree based probability measures. The proposed LInE metric which provides an effective way to estimate the influence of a link in the network and incorporates this influence to identify nodal characteristics, performs better compared to degree based entropy. We found that LInE can differentiate various network types which degree-based or betweenness centrality based node influence metrics cannot. Our findings show that spatial wireless networks and regular grid networks, respectively, have lowest and highest LInE values. Finally, performance analysis of LInE is carried out on a real-world network as well as on a wireless mesh network testbed to study the influence of our metric as well as influence stability of nodes in dynamic networks.

  15. Secure Link Middleware

    Science.gov (United States)

    2008-08-01

    Secure Link middleware as specified by the circled ‘sld’, sld . Using a network traffic analyzer (e.g., tcpdump) at router bulldog and tiger, ARL...or nfs (remote accessing file systems) to be securely operated and used among networked computer systems without any bulldog (router3) bear (router2

  16. Enso modulations on streamflow characteristics

    OpenAIRE

    Yerdelen Cahit; Marti Ali Ihsan; Kahya Ercan

    2011-01-01

    El Niño Southern Oscillation (ENSO) has been linked to climate and hydrologic anomalies throughout the world. This paperpresents how ENSO modulates the basic statistical characteristics of streamflow time series that is assumed to be affected byENSO. For this we first considered hypothetical series that can be obtained from the original series at each station by assumingnon-occurrence of El Niño events in the past. Instead those data belonging to El Niño years were simulated by the RadialBase...

  17. First results with the Gigabit Link Interface Board (GLIB)

    CERN Document Server

    Vichoudis, P; Baron, S; Bobillier, V; Haas, S; Hansen, M; Joos, M; Lobato Pardavila, L; Vasey, F

    2011-01-01

    We have designed and built an FPGA-based platform for users of high speed optical links in high energy physics experiments. The Gigabit Link Interface Board (GLIB) serves both as a platform for the evaluation of optical links in the laboratory as well as a triggering and/or data acquisition system in beam or irradiation tests of detector modules. The GLIB is a double width Advanced Mezzanine Card (AMC) that is used either stand-alone or inside a micro Telecommunications Computing Architecture (muTCA) crate. This paper presents the first results with the GLIB prototype delivered in 2011.

  18. Module utilization committee

    Science.gov (United States)

    Volkmer, K.; Praver, G.

    1984-01-01

    Photovoltaic collector modules were declared surplus to the needs of the U.S. Dept. of Energy. The Module Utilization Committee was formed to make appropriate disposition of the surplus modules on a national basis and to act as a broker for requests for these modules originating outside of the National Photovoltaics Program.

  19. MI 4010 Thermoelectric Modules.

    Science.gov (United States)

    The report covers the design justification, physical specification and characterization of the MI 4010 module . The purpose of the contract was to...demonstrate the capability to fabricate pieceparts, process into assemblies, and test thermoelectric modules equivalent to the module used in the Hand...Held Thermal Viewer. The completed modules were also subjected to limited demonstration tests of reliability and useful life.

  20. A neural link between generosity and happiness

    Science.gov (United States)

    Park, Soyoung Q.; Kahnt, Thorsten; Dogan, Azade; Strang, Sabrina; Fehr, Ernst; Tobler, Philippe N.

    2017-01-01

    Generous behaviour is known to increase happiness, which could thereby motivate generosity. In this study, we use functional magnetic resonance imaging and a public pledge for future generosity to investigate the brain mechanisms that link generous behaviour with increases in happiness. Participants promised to spend money over the next 4 weeks either on others (experimental group) or on themselves (control group). Here, we report that, compared to controls, participants in the experimental group make more generous choices in an independent decision-making task and show stronger increases in self-reported happiness. Generous decisions engage the temporo-parietal junction (TPJ) in the experimental more than in the control group and differentially modulate the connectivity between TPJ and ventral striatum. Importantly, striatal activity during generous decisions is directly related to changes in happiness. These results demonstrate that top–down control of striatal activity plays a fundamental role in linking commitment-induced generosity with happiness. PMID:28696410

  1. Optical coherent and envelope detection for photonic wireless communication links

    DEFF Research Database (Denmark)

    Prince, Kamau; Zibar, Darko; Yu, Xianbin;

    We present two novel optical detection techniques for radio over fiber (RoF) communication links. Firstly, we present recent results obtained with optical digital coherent detection of optical phase-modulated ROF signals supporting error-free transmission over 25 km standard SMF with BPSK and QPSK...

  2. Investigation of performance of UPFC without DC link capacitor

    Energy Technology Data Exchange (ETDEWEB)

    Geethalakshmi, B. [Department of EEE, Pondicherry Engineering College, Pondicherry (India); Dananjayan, P. [Department of ECE, Pondicherry Engineering College, Pondicherry (India)

    2008-04-15

    This paper presents an analysis of the dynamic operation of unified power flow controller without DC link capacitor. In this scheme of UPFC the shunt converter present in the static synchronous compensator is operated as a current source rectifier, which maintains a fixed DC voltage and DC current on the DC link without capacitor. The capacitor in the DC link is replaced by an AC filter on the line side with a very small value to reduce higher order harmonics. The voltage source inverter present in the series compensator is operated with space vector modulation technique. The proposed scheme is fully validated through digital simulation. The simulated results show that the DC link voltage is maintained constant without DC link capacitor; STATCOM provides good voltage regulation and static synchronous series compensator influences power flow over the transmission line. Transient responses of single machine infinite bus power system have also been presented. (author)

  3. Volumes of chain links

    CERN Document Server

    Kaiser, James; Rollins, Clint

    2011-01-01

    Agol has conjectured that minimally twisted n-chain links are the smallest volume hyperbolic manifolds with n cusps, for n at most 10. In his thesis, Venzke mentions that these cannot be smallest volume for n at least 11, but does not provide a proof. In this paper, we give a proof of Venzke's statement. The proof for n at least 60 is completely rigorous. The proof for n between 11 and 59 uses a computer calculation, and can be made rigorous for manifolds of small enough complexity, using methods of Moser and Milley. Finally, we prove that the n-chain link with 2m or 2m+1 half-twists cannot be the minimal volume hyperbolic manifold with n cusps, provided n is at least 60 or |m| is at least 8, and we give computational data indicating this remains true for smaller n and |m|.

  4. Multifunctional fiber-optic microwave links based on remote heterodyne detection

    DEFF Research Database (Denmark)

    Gliese, Ulrik Bo; Nielsen, Torben Nørskov; Nielsen, Søren Nørskov

    1998-01-01

    The multifunctionality of microwave links based on remote heterodyne detection (RHD) of signals from a dual-frequency laser transmitter is discussed and experimentally demonstrated in this paper. Typically, direct detection (DD) in conjunction with optical intensity modulation is used to implemen...... carrier to a 9-GHz carrier with penalty-free transmission over 25 km of optical fiber. Finally, the transparent link transmits a standard FM video 7.6-GHz radio-link signal over 25 km of optical fiber without measurable distortion...... fiber-optic microwave links. The resulting links are inherently transparent. As opposed to DD links, RHD links can perform radio-system functionalities such as modulation and frequency conversion in addition to transparency. All of these three functionalities are presented and experimentally...

  5. 80 Gbit/s 16-QAM Multicarrier THz Wireless Communication Link in the 400 GHz Band

    DEFF Research Database (Denmark)

    Jia, Shi; Yu, Xianbin; Hu, Hao;

    2016-01-01

    We experimentally demonstrate a high-speed multicarrier THz wireless communication system operating in the 400 GHz band. The use of spectrally efficient 16-QAM modulation and broadband THz transceivers enable link data rates up to 80 Gbit/s....

  6. Linking assumptions in amblyopia

    Science.gov (United States)

    LEVI, DENNIS M.

    2017-01-01

    Over the last 35 years or so, there has been substantial progress in revealing and characterizing the many interesting and sometimes mysterious sensory abnormalities that accompany amblyopia. A goal of many of the studies has been to try to make the link between the sensory losses and the underlying neural losses, resulting in several hypotheses about the site, nature, and cause of amblyopia. This article reviews some of these hypotheses, and the assumptions that link the sensory losses to specific physiological alterations in the brain. Despite intensive study, it turns out to be quite difficult to make a simple linking hypothesis, at least at the level of single neurons, and the locus of the sensory loss remains elusive. It is now clear that the simplest notion—that reduced contrast sensitivity of neurons in cortical area V1 explains the reduction in contrast sensitivity—is too simplistic. Considerations of noise, noise correlations, pooling, and the weighting of information also play a critically important role in making perceptual decisions, and our current models of amblyopia do not adequately take these into account. Indeed, although the reduction of contrast sensitivity is generally considered to reflect “early” neural changes, it seems plausible that it reflects changes at many stages of visual processing. PMID:23879956

  7. Collaboratively Patching Linked Data

    CERN Document Server

    Knuth, Magnus; Sack, Harald

    2012-01-01

    Today's Web of Data is noisy. Linked Data often needs extensive preprocessing to enable efficient use of heterogeneous resources. While consistent and valid data provides the key to efficient data processing and aggregation we are facing two main challenges: (1st) Identification of erroneous facts and tracking their origins in dynamically connected datasets is a difficult task, and (2nd) efforts in the curation of deficient facts in Linked Data are exchanged rather rarely. Since erroneous data often is duplicated and (re-)distributed by mashup applications it is not only the responsibility of a few original publishers to keep their data tidy, but progresses to be a mission for all distributers and consumers of Linked Data too. We present a new approach to expose and to reuse patches on erroneous data to enhance and to add quality information to the Web of Data. The feasibility of our approach is demonstrated by example of a collaborative game that patches statements in DBpedia data and provides notifications ...

  8. X linked mental retardation.

    Science.gov (United States)

    Rejeb, Imen; Ben Jemaa, Lamia; Chaabouni, Habiba

    2009-05-01

    Mental retardation (MR) is a group of heterogeneous clinical conditions. There are more than 900 genetic disorders associated with MR and it affects around 3% of the general population. Many MR conditions described are syndromic, fragile X syndrome being the most common clinical entity among them. X linked mental retardation (XLMR) is subdivided in two categories: syndromic XLMR (MRXS) when MR is associated with clinical features and non-syndromic XLMR (MRX) when MR is isolated. The aim of this systematic review of the literature was to join together the results of several studies related to X linked mental retardation and to present various genes implicated in this disease. In this review, focus has been given on genes implicated in mental retardation, the clinical data and on phenotype-genotype correlations. An exhaustive electronic and library research of the recent literature was carried out on the Web sites "Science Direct" and "Interscience Wiley". The key words used were "mental retardation", "X chromosome", "gene", "syndromic mental retardation", "non-syndromic mental retardation". In this review a number of X linked genes, the clinical features associated with the gene abnormality, and the prevalence of the disease gene are discussed. We classified these genes by order of their first implication in MR. A table presented on the XLMR Update Web site who list the 82 known XLMR genes is available as XLMR Genes and corresponding proteins.

  9. High-speed analog fiber optic links for satellite communication

    Science.gov (United States)

    Daryoush, A. S.; Herczfeld, P. R.; Kunath, R. R.

    1988-01-01

    Large-aperture phased array antennas operating at millimeter wave frequencies are designed for space-based communications and imaging. Array elements are comprised of active transmit/receive (T/R) modules which are linked to the central processing unit through a high-speed fiberoptic network. This paper demonstrates optical control of active modules for satellite communication at 24 GHz. An approach called T/R level data mixing, which utilizes fiberoptic transmission of a data signal to individual T/R modules to be upconverted by an optically synchronized local oscillator, is demonstrated at 24 GHz. A free-running HEMT oscillator, used as local oscillator at 24 GHz, is synchronized using indirect subharmonic optical injection locking over a locking range of 14 MHz. Results of data link performance over 500-1000 MHz is also reported in terms of gain-bandwidth, linearity and third-order intercept, sensitivity, and dynamic range.

  10. Improving the capacity of short-reach VCSEL-based MMF optical links

    DEFF Research Database (Denmark)

    Tatarczak, Anna; Lu, Xiaofeng; Tafur Monroy, Idelfonso

    2016-01-01

    We summarize strategies for increasing a capacity of short-reach links that base on an 850 nm VCSEL and an MMF. Presented methods include advanced modulation formats, equalization, WDM, quasi-single mode sources and a selective mode launch.......We summarize strategies for increasing a capacity of short-reach links that base on an 850 nm VCSEL and an MMF. Presented methods include advanced modulation formats, equalization, WDM, quasi-single mode sources and a selective mode launch....

  11. O-band 400 Gbit/s client side optical transmission link

    DEFF Research Database (Denmark)

    Zuo, Tianjian; Tatarczak, Anna; Iglesias Olmedo, Miguel

    2014-01-01

    We present an O-band 400 Gbit/s optical client side Ethernet link with 40 km SSMF reach employing four LAN-WDM lanes, MultiCAP modulation and direct detection.......We present an O-band 400 Gbit/s optical client side Ethernet link with 40 km SSMF reach employing four LAN-WDM lanes, MultiCAP modulation and direct detection....

  12. Optical frequency tripling with improved suppression and sideband selection.

    Science.gov (United States)

    Thakur, Manoj P; Medeiros, Maria C R; Laurêncio, Paula; Mitchell, John E

    2011-12-12

    A novel optical dispersion tolerant millimetre-wave radio-over-fibre system using optical frequency tripling technique with enhanced and selectable sideband suppression is demonstrated. The implementation utilises cascaded optical modulators to achieve either an optical single sideband (OSSB) or double sideband-suppressed carrier (DSB-SC) signal with high sideband suppression. Our analysis and simulation results indicate that the achievable suppression ratio of this configuration is only limited by other system factors such as optical noise and drifting of the operational conditions. The OSSB transmission system performance is assessed experimentally by the transport of 4 WiMax channels modulating a 10 GHz optical upconverted RF carrier as well as for optical frequency doubling and tripling. The 10 GHz and tripled carrier at 30 GHz are dispersion tolerant resulting both in an average relative constellation error (RCE) of -28.7 dB after 40 km of fibre.

  13. Polychlorinated biphenyls and links to cardiovascular disease.

    Science.gov (United States)

    Perkins, Jordan T; Petriello, Michael C; Newsome, Bradley J; Hennig, Bernhard

    2016-02-01

    The pathology of cardiovascular disease is multi-faceted, with links to many modifiable and non-modifiable risk factors. Epidemiological evidence now implicates exposure to persistent organic pollutants, such as polychlorinated biphenyls (PCBs), with an increased risk of developing diabetes, hypertension, and obesity; all of which are clinically relevant to the onset and progression of cardiovascular disease. PCBs exert their cardiovascular toxicity either directly or indirectly via multiple mechanisms, which are highly dependent on the type and concentration of PCBs present. However, many PCBs may modulate cellular signaling pathways leading to common detrimental outcomes including induction of chronic oxidative stress, inflammation, and endocrine disruption. With the abundance of potential toxic pollutants increasing globally, it is critical to identify sensible means of decreasing associated disease risks. Emerging evidence now implicates a protective role of lifestyle modifications such as increased exercise and/or nutritional modulation via anti-inflammatory foods, which may help to decrease the vascular toxicity of PCBs. This review will outline the current state of knowledge linking coplanar and non-coplanar PCBs to cardiovascular disease and describe the possible molecular mechanism of this association.

  14. Knots and links

    CERN Document Server

    Rolfsen, Dale

    2003-01-01

    Rolfsen's beautiful book on knots and links can be read by anyone, from beginner to expert, who wants to learn about knot theory. Beginners with a basic background find an inviting introduction to the elements of topology, emphasizing the tools needed for understanding knots, the fundamental group and van Kampen's theorem, for example, which are then applied to concrete problems, such as computing knot groups. For experts, Rolfsen explains advanced topics, such as the connections between knot theory and surgery and how they are useful to understanding three-manifolds. Besides providing a guide

  15. The weakest link

    Energy Technology Data Exchange (ETDEWEB)

    Lumley, G. [GBI Consulting, Qld. (Australia)

    2005-08-01

    In part seven of his series on dragline productivity, the author tackles the subject of the dump rope, the weakest link in the operation of the dragline, is traded. Five factors have been identified as critical to dump life: ratio of dump block to dump rope diameter; excessive loads in dumps rope; rope abrasion against dump block; rope abrasion against bucket; dump rope construction. These factors are considered in the article. The author comments that in the drive to increase dragline productivity, rope life has been sacrificed. 4 figs., 1 tab.

  16. Linking consumer experiences

    DEFF Research Database (Denmark)

    Smed, Karina Madsen

    Consumers consume products in various ways serving a number of purposes. Much attention has been paid to experiences attached to consumption, sometimes very explicitly, e.g. in tourism, the essence of which is experiences of various sorts, but often also implicitly as internalised experiences...... become part of the individual self, worldview, and behaviour. This paper seeks to explore links between consumer experiences through the exploration of narrative sequences in travel blogs. Findings indicate that non-consumption is a central element to the bloggers and also indicative of a community...

  17. EEE Links. Volume 5

    Science.gov (United States)

    Humphrey, Robert (Editor)

    1999-01-01

    The EEE Links Newsletter is a quarterly publication produced by Code 562 in support of the NASA HQ funded NASA Electronic Parts and Packaging (NEPP) Program. The newsletter is produced as an electronic format deliverable made available via the referenced www site administered by Code 562, The newsletter publishes brief articles on topics of interest to NASA programs and projects in the area of electronic parts and packaging. The newsletter does not provide information pertaining to patented or proprietary information. The information provided is at the level of that produced by industry and university researchers and is published at national and international conferences.

  18. Modulation properties of VCSEL with intracavity modulator

    Science.gov (United States)

    van Eisden, J.; Yakimov, M.; Tokranov, V.; Varanasi, M.; Mohammed, E. M.; Young, I. A.; Oktyabrsky, S.

    2007-02-01

    We have studied the modulation properties of VCSEL with intracavity multiple quantum well (MQW) electroabsorption modulator integrated into the top distributed Bragg reflector (DBR) [1]. Small signal analysis of rate equations for loss modulation shows an intrinsic high-frequency roll-off slope of 1/ω instead of 1/ω2 in directly modulated laser diodes, and consequently bandwidths in excess of 40 GHz are obtainable with this configuration [2]. Possible limiting factors to high bandwidth were examined by fitting high frequency characteristics to a multi-pole transfer function, and include RC delay and carrier drift-limited time of flight (TOF) in the modulator intrinsic region. Intracavity loss modulation shows a strong (+20dB) relaxation oscillation resonant feature in both theory and experiment. As demonstrated, this feature can be significantly reduced in amplitude using parasitics. We have extracted relative contribution of TOF and parasitic capacitance by varying the modulator intrinsic region width (105 and 210 nm) and lateral size of the modulator (18 and 12μm). It was estimated that the small size modulator exhibits parasitics f -3dB at 8GHz. To estimate the carrier TOF contribution to bandwidth limits, low temperature growth of a 210 nm absorber i-region and MQW was employed to reduce photogenerated carrier lifetime. Bandwidth limitations were found to be mostly due to diode and metallization capacitances, in addition to one pole set by the optoelectronic resonance frequency. We have used p-modulation doping of the gain region to increase the relaxation frequency. Pronounced active Q-switching was observed, yielding pulse widths of 40 ps at a 4 GHz rate.

  19. CDC 7600 module slice

    CERN Multimedia

    Each module contained 8 circuit cards for a total of about 300-500 uncovered transistors packaged with face plates so the Freon plates wouldn't touch the circuits. (cooling plates that surrounded each module).

  20. Koszul differential graded modules

    Institute of Scientific and Technical Information of China (English)

    HE JiWei; WU QuanShui

    2009-01-01

    The concept of Koszulity for differential graded (DG, for short) modules is introduced. It is shown that any bounded below DG module with bounded Ext-group to the trivial module over a Koszul DG algebra has a Koszul DG submodule (up to a shift and truncation), moreover such a DG module can be approximated by Koszul DG modules (Theorem 3.6). Let A be a Koszul DG algebra, and Dc (A) be the full triangulated subcategory of the derived category of DG A-modules generated by the object AA. If the trivial DG module kA lies in Dc(A), then the heart of the standard t-structure on Dc(A) is anti-equivalent to the category of finitely generated modules over some finite dimensional algebra. As a corollary, Dc(A) is equivalent to the bounded derived category of its heart as triangulated categories.

  1. Koszul differential graded modules

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    The concept of Koszulity for differential graded (DG, for short) modules is introduced. It is shown that any bounded below DG module with bounded Ext-group to the trivial module over a Koszul DG algebra has a Koszul DG submodule (up to a shift and truncation), moreover such a DG module can be approximated by Koszul DG modules (Theorem 3.6). Let A be a Koszul DG algebra, and Dc(A) be the full triangulated subcategory of the derived category of DG A-modules generated by the object AA. If the trivial DG module kA lies in Dc(A), then the heart of the standard t-structure on Dc(A) is anti-equivalent to the category of finitely generated modules over some finite dimensional algebra. As a corollary, Dc(A) is equivalent to the bounded derived category of its heart as triangulated categories.

  2. Single Carrier Architecture for High Data Rate Wireless PAN Communications System

    CERN Document Server

    Rakotondrainibe, Lahatra; Zaharia, Gheorghe; Grunfelder, Guy; Zein, Ghaïs El

    2010-01-01

    A 60 GHz wireless Gigabit Ethernet (G.E.) communication system is developed at IETR. As the 60 GHz radio link operates only in a single-room configuration, an additional Radio over Fibre (RoF) link is used to ensure the communications in all the rooms of a residential environment. The realized system covers 2 GHz bandwidth. Due to the hardware constraints, a symbol rate at 875 Mbps is attained using simple single carrier architecture. In the baseband (BB) processing block, an original byte/frame synchronization process is designed to provide a smaller value of the preamble missing detection and false alarm probabilities. Bit error rate (BER) measurements have been realized in a large gym for line-of-sight (LOS) conditions. A Tx-Rx distance greater than 30 meters was attained with low BER using high gain antennas and forward error correction RS (255, 239) coding.

  3. Optical links in handheld multimedia devices

    Science.gov (United States)

    van Geffen, S.; Duis, J.; Miller, R.

    2008-04-01

    Ever emerging applications in handheld multimedia devices such as mobile phones, laptop computers, portable video games and digital cameras requiring increased screen resolutions are driving higher aggregate bitrates between host processor and display(s) enabling services such as mobile video conferencing, video on demand and TV broadcasting. Larger displays and smaller phones require complex mechanical 3D hinge configurations striving to combine maximum functionality with compact building volumes. Conventional galvanic interconnections such as Micro-Coax and FPC carrying parallel digital data between host processor and display module may produce Electromagnetic Interference (EMI) and bandwidth limitations caused by small cable size and tight cable bends. To reduce the number of signals through a hinge, the mobile phone industry, organized in the MIPI (Mobile Industry Processor Interface) alliance, is currently defining an electrical interface transmitting serialized digital data at speeds >1Gbps. This interface allows for electrical or optical interconnects. Above 1Gbps optical links may offer a cost effective alternative because of their flexibility, increased bandwidth and immunity to EMI. This paper describes the development of optical links for handheld communication devices. A cable assembly based on a special Plastic Optical Fiber (POF) selected for its mechanical durability is terminated with a small form factor molded lens assembly which interfaces between an 850nm VCSEL transmitter and a receiving device on the printed circuit board of the display module. A statistical approach based on a Lean Design For Six Sigma (LDFSS) roadmap for new product development tries to find an optimum link definition which will be robust and low cost meeting the power consumption requirements appropriate for battery operated systems.

  4. CDC 6600 Cordwood Module

    CERN Multimedia

    1964-01-01

    The CDC 6600 cordwood module containing 64 silicon transistors. The module was mounted between two plates that were cooled conductive by a refrigeration unit via the front panel. The construction of this module uses the cord method, so called because the resistors seem to be stacked like cord between the two circuit boards in order to obtain a high density. The 6600 model contained nearly 6,000 such modules.

  5. On Matlis dualizing modules

    Directory of Open Access Journals (Sweden)

    Edgar E. Enochs

    2002-01-01

    Full Text Available We consider rings admitting a Matlis dualizing module E. We argue that if R admits two such dualizing modules, then a module is reflexive with respect to one if and only if it is reflexive with respect to the other. Using this fact we argue that the number (whether finite or infinite of distinct dualizing modules equals the number of distinct invertible (R,R-bimodules. We show by example that this number can be greater than one.

  6. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... Projects » Learn the Link - Drugs and HIV Learn the Link - Drugs and HIV Email Facebook Twitter 2005 – ... and to help us Send the Message . Get the Facts What are HIV and AIDS? HIV (human ...

  7. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... the link between drug abuse and HIV infection. It contains information for young people, parents and teachers, ... present time. The virus (HIV) and the disease it causes (AIDS) are often linked and referred to ...

  8. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... the Link - Drugs and HIV Learn the Link - Drugs and HIV Email Facebook Twitter 2005 –Ongoing Behaviors ... GA: CDC, DHHS. Retrieved June 2012 How are Drug Abuse and HIV Related? Drug abuse and addiction ...

  9. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... the Link - Drugs and HIV Learn the Link - Drugs and HIV Email Facebook Twitter 2005 –Ongoing Behaviors ... GA: CDC, DHHS. Retrieved June 2012 How are Drug Abuse and HIV Related? Drug abuse and addiction ...

  10. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... the link between drug abuse and HIV infection. It contains information for young people, parents and teachers, ... present time. The virus (HIV) and the disease it causes (AIDS) are often linked and referred to ...

  11. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... Projects » Learn the Link - Drugs and HIV Learn the Link - Drugs and HIV Email Facebook Twitter 2005 – ... and to help us Send the Message . Get the Facts What are HIV and AIDS? HIV (human ...

  12. Modulating lignin in plants

    Science.gov (United States)

    Apuya, Nestor; Bobzin, Steven Craig; Okamuro, Jack; Zhang, Ke

    2013-01-29

    Materials and methods for modulating (e.g., increasing or decreasing) lignin content in plants are disclosed. For example, nucleic acids encoding lignin-modulating polypeptides are disclosed as well as methods for using such nucleic acids to generate transgenic plants having a modulated lignin content.

  13. Relatively Endocoherent Modules

    Institute of Scientific and Technical Information of China (English)

    Lixin Mao

    2007-01-01

    Let MR be a right R-module over a ring R with S= End(MR)We study the coherence of the left S-module sM relative to a torsion theory for the category of right R-modules.Various results are developed, many extending known results.

  14. Polarization modulators for CMBPol

    Energy Technology Data Exchange (ETDEWEB)

    Ade, P A R; Savini, G [Cardiff University, School of Physics and Astronomy, Queens Buildings, The Parade, Cardiff, CF24 3AA (United Kingdom); Chuss, D T [NASA Goddard Space Flight Center, Code 665, Greenbelt, MD, 20771 (United States); Hanany, S [School of Physics and Astronomy, University of Minnesota/Twin Cities, Minneapolis, MN, 55455 (United States); Haynes, V; Pisano, G [University of Manchester, School of Physics and Astronomy - Alan Turing Building, Upper Brooke street, Manchester, M13 4PL (United Kingdom); Keating, B G [Department of Physics, University of California, San Diego, La Jolla, CA 92093-0424 (United States); Kogut, A [Code 665 Goddard Space Flight Center, Greenbelt, MD 20771 (United States); Ruhl, J E [Physics Department, Case Western Reserve University, Cleveland, OH, 44106 (United States); Wollack, E J [Observational Cosmology Laboratory, NASA/GSFC, Greenbelt, MD 20771 (United States)

    2009-03-01

    We review a number of technologies that are candidates for active polarization modulators for CMBPol. The technologies are appropriate for instruments that use bolometric detectors and include birefringent crystal-based and metal-mesh-based half-wave plates, variable phase polarization modulator, Faraday rotator, and photolithographed modulators. We also give a current account of the status of millimeter-wave orthomode transducers.

  15. MI 6040 Thermoelectric Modules.

    Science.gov (United States)

    The report covers the design justification, physical specification and characterization of the MI 6040 module . The purpose of the thermoelectric... modules is the cooling of infrared detector arrays to temperature of 170K or colder. The completed modules were also subjected to limited demonstration tests of reliability and useful life.

  16. Gigahertz optical modulation.

    Science.gov (United States)

    Riesz, R P; Biazzo, M R

    1969-07-01

    Light pulses from a mode-locked He-Ne laser have been modulated by a LiTaO(3) electrooptic crystal mounted on a thin film substrate. The crystal was driven by pulses from a GaAs Gunn effect diode. Amplitude modulation of 20% has been achieved at 2 GHz for a single pass through the modulator.

  17. STRS SpaceWire FPGA Module

    Science.gov (United States)

    Lux, James P.; Taylor, Gregory H.; Lang, Minh; Stern, Ryan A.

    2011-01-01

    An FPGA module leverages the previous work from Goddard Space Flight Center (GSFC) relating to NASA s Space Telecommunications Radio System (STRS) project. The STRS SpaceWire FPGA Module is written in the Verilog Register Transfer Level (RTL) language, and it encapsulates an unmodified GSFC core (which is written in VHDL). The module has the necessary inputs/outputs (I/Os) and parameters to integrate seamlessly with the SPARC I/O FPGA Interface module (also developed for the STRS operating environment, OE). Software running on the SPARC processor can access the configuration and status registers within the SpaceWire module. This allows software to control and monitor the SpaceWire functions, but it is also used to give software direct access to what is transmitted and received through the link. SpaceWire data characters can be sent/received through the software interface, as well as through the dedicated interface on the GSFC core. Similarly, SpaceWire time codes can be sent/received through the software interface or through a dedicated interface on the core. This innovation is designed for plug-and-play integration in the STRS OE. The SpaceWire module simplifies the interfaces to the GSFC core, and synchronizes all I/O to a single clock. An interrupt output (with optional masking) identifies time-sensitive events within the module. Test modes were added to allow internal loopback of the SpaceWire link and internal loopback of the client-side data interface.

  18. ITK optical links backup document

    CERN Document Server

    Huffman, B T; The ATLAS collaboration; Flick, T; Ye, J

    2013-01-01

    This document describes the proposed optical links to be used for the ITK in the phase II upgrade. The current R&D for optical links pursued in the Versatile Link group is reviewed. In particular the results demonstrating the radiation tolerance of all the on-detector components are documented. The bandwidth requirements and the resulting numerology are given.

  19. Hyperbolic semi-adequate links

    OpenAIRE

    Futer, David; Kalfagianni, Efstratia; Purcell, Jessica S.

    2013-01-01

    We provide a diagrammatic criterion for semi-adequate links to be hyperbolic. We also give a conjectural description of the satellite structures of semi-adequate links. One application of our result is that the closures of sufficiently complicated positive braids are hyperbolic links.

  20. Martel's links with USA

    Directory of Open Access Journals (Sweden)

    Trevor Shaw

    1997-01-01

    Full Text Available Of the 29% foreign members in the Société de Spéléologie, five lived in USA. They were Luella Owen (the only woman member of the Société, R. Ellsworth Cali, H.C. Hovey, E Van Epps and C. R. Blackall. E.S. Balch, though not a member, also knew Martel. These members, between them, published ten papers in Spelunca, which also reviewed their other work. The activities of these six, and their links with France, are discussed. Martel actively encouraged cave work in America, as elsewhere, and Hovey, who had been with him during the survey of Aven Armand, he knew quite well. In 1912 Martel at last visited USA himself and the barometer readings he took in Mamoth Cave to measure altitude enabled him to draw the first longitudinal section of the cave since 1835.

  1. Linking place and mind

    DEFF Research Database (Denmark)

    Jensen, Marie Møller

    2016-01-01

    This paper investigates the salience of vernacular Tyneside forms on the basis of theories of enregisterment and exemplar processing. On one level, exemplar theory provides a psycholinguistic account of how the link between social value and linguistic features is possible. Conversely, integrating...... the notion of social value into exemplar theory extends the value of this originally cognitive theory to social domains. It is suggested that the association of social value and particular local, linguistic forms may contribute to the salience of these forms among local speakers. The empirical work reported...... here takes the form of a questionnaire study, which aims to uncover Tyneside inhabitants' awareness of forms as well as their affiliation with the local community. Results showed differences in frequency perceptions between participants themselves and others which indicate that speakers can identify...

  2. Coherent integrated receiver for highly linear microwave photonic links

    Science.gov (United States)

    Klamkin, Jonathan

    Phase modulation can be used to improve the signal-to-noise ratio and spurfree dynamic range (SFDR) of microwave photonic links because phase modulation is not limited in input modulation swing and is inherently linear using certain electro-optic devices. Traditional interferometer-based phase demodulators have a sinusoidal response therefore a novel approach is required for achieving linear coherent detection at the receive end of a photonic link employing phase modulation. In this work, a balanced receiver with feedback to a reference tracking phase modulator was developed. With sufficient feedback loop gain, the received signal phase is closely tracked and the phase detection falls within the linear regime of the interferometer response. For stable operation at high frequency the delay of the feedback loop must be kept short, therefore a monolithic approach is required to realize a compact receiver architecture. The monolithic photonic integrated circuit (PIC) developed here consists of a high power balanced uni-traveling-carrier photodiode (UTC-PD), a compact 2x2 multimode interference (MMI) coupler, and multi-quantum well reference phase modulators. This PIC is hybrid integrated with an electronic IC that provides transconductance amplification of the feedback signal for increased loop gain. Novel concepts such as charge compensation, partially depleted absorption, and absorption profile modification were incorporated into the design of the waveguide UTCPDs resulting in record output saturation current and linearity. Both general interference surface ridge (SR) MMI couplers and restricted interference deep ridge (DR) MMI couplers were explored, the latter for reducing the loop delay. Current injection tuning was incorporated into the MMI couplers for fine tuning the output power splitting ratio. The quantum well design of the reference phase modulators was optimized for realizing low Vpi, low insertion loss, low absorption modulation, and improved linearity

  3. Divisible ℤ-modules

    Directory of Open Access Journals (Sweden)

    Futa Yuichi

    2016-03-01

    Full Text Available In this article, we formalize the definition of divisible ℤ-module and its properties in the Mizar system [3]. We formally prove that any non-trivial divisible ℤ-modules are not finitely-generated.We introduce a divisible ℤ-module, equivalent to a vector space of a torsion-free ℤ-module with a coefficient ring ℚ. ℤ-modules are important for lattice problems, LLL (Lenstra, Lenstra and Lovász base reduction algorithm [15], cryptographic systems with lattices [16] and coding theory [8].

  4. Quantum Modelling of Electro-Optic Modulators

    CERN Document Server

    Capmany, Jose

    2011-01-01

    Many components that are employed in quantum information and communication systems are well known photonic devices encountered in standard optical fiber communication systems, such as optical beamsplitters, waveguide couplers and junctions, electro-optic modulators and optical fiber links. The use of these photonic devices is becoming increasingly important especially in the context of their possible integration either in a specifically designed system or in an already deployed end-to-end fiber link. Whereas the behavior of these devices is well known under the classical regime, in some cases their operation under quantum conditions is less well understood. This paper reviews the salient features of the quantum scattering theory describing both the operation of the electro-optic phase and amplitude modulators in discrete and continuous-mode formalisms. This subject is timely and of importance in light of the increasing utilization of these devices in a variety of systems, including quantum key distribution an...

  5. Reduced Multiplication Modules

    Indian Academy of Sciences (India)

    Karim Samei

    2011-05-01

    An -module is called a multiplication module if for each submodule of , = for some ideal of . As defined for a commutative ring , an -module is said to be reduced if the intersection of prime submodules of is zero. The prime spectrum and minimal prime submodules of the reduced module are studied. Essential submodules of are characterized via a topological property. It is shown that the Goldie dimension of is equal to the Souslin number of Spec (). Also a finitely generated module is a Baer module if and only if Spec () is an extremally disconnected space; if and only if it is a -module. It is proved that a prime submodule is minimal in if and only if for each $x\\in N,\\mathrm{Ann}(x)\

  6. Solar cell module. Taiyo denchi module

    Energy Technology Data Exchange (ETDEWEB)

    Nakano, Akihiko.

    1990-01-24

    This invention concerns a module frame of solar cell and a solar cell module using this frame. In particular, it concerns a frame and a module useful for the CdS/CdTe or CdS/CuInSe {sub 2} based cell. In the existing solar cell module, sealant is packed in between the edges of a glass substrate, a resin layer and a back protective thin film, etc. and a grooved frame of U-shaped section. For the sealant, silicon based resin and butyl rubber based resin are used many times, but either resin has defects such as their overflow from the module structure. In order to solve these defects, this invention proposes to provide stair-shaped protrusions along the four sides of the bottom of the box frame (herein after called the lower frame) of the module and at the same time, provide a groove for pooling the sealant at the portion where such protrusion meets the side wall, furthermore to provide depressions for pooling the sealant at the upper edge inside the side wall of the lower frame or to punch holes at the corners of the bottom of the lower frame. 9 figs.

  7. Phase-Modulated Optical Communication Systems

    CERN Document Server

    Ho, Keang-Po

    2005-01-01

    Fiber-optic communication systems have revolutionized our telecommunication infrastructures – currently, almost all telephone land-line, cellular, and internet communications must travel via some form of optical fibers. In these transmission systems, neither the phase nor frequency of the optical signal carries information – only the intensity of the signal is used. To transmit more information in a single optical carrier, the phase of the optical carrier must be explored. As a result, there is renewed interest in phase-modulated optical communications, mainly in direct-detection DPSK signals for long-haul optical communication systems. When optical amplifiers are used to maintain certain signal level among the fiber link, the system is limited by amplifier noises and fiber nonlinearities. Phase-Modulated Optical Communication Systems surveys this newly popular area, covering the following topics: The transmitter and receiver for phase-modulated coherent lightwave systems Method for performance analysis o...

  8. Force Factor Modulation in Electro Dynamic Loudspeakers

    DEFF Research Database (Denmark)

    Risbo, Lars; Agerkvist, Finn T.; Tinggaard, Carsten

    2016-01-01

    The relationship between the non-linear phenomenon of ’reluctance force’ and the position dependency of the voice coil inductance was established in 1949 by Cunningham, who called it ’magnetic attraction force’. This paper revisits Cunningham’s analysis and expands it into a generalised form...... that includes the frequency dependency and applies to coils with non-inductive (lossy) blocked impedance. The paper also demonstrates that Cunningham’s force can be explained physically as a modulation of the force factor which again is directly linked to modulation of the flux of the coil. A verification based...... on both experiments and simulations is presented along discussions of the impact of force factor modulation for various motor topologies. Finally, it is shown that the popular L2R2 coil impedance model does not correctly predict the force unless the new analysis is applied....

  9. Force Factor Modulation in Electro Dynamic Loudspeakers

    DEFF Research Database (Denmark)

    Risbo, Lars; Agerkvist, Finn T.; Tinggaard, Carsten

    2016-01-01

    The relationship between the non-linear phenomenon of ’reluctance force’ and the position dependency of the voice coil inductance was established in 1949 by Cunningham, who called it ’magnetic attraction force’. This paper revisits Cunningham’s analysis and expands it into a generalised form that...... on both experiments and simulations is presented along discussions of the impact of force factor modulation for various motor topologies. Finally, it is shown that the popular L2R2 coil impedance model does not correctly predict the force unless the new analysis is applied....... that includes the frequency dependency and applies to coils with non-inductive (lossy) blocked impedance. The paper also demonstrates that Cunningham’s force can be explained physically as a modulation of the force factor which again is directly linked to modulation of the flux of the coil. A verification based...

  10. Exploring the significance of human mobility patterns in social link prediction

    KAUST Repository

    Alharbi, Basma Mohammed

    2014-01-01

    Link prediction is a fundamental task in social networks. Recently, emphasis has been placed on forecasting new social ties using user mobility patterns, e.g., investigating physical and semantic co-locations for new proximity measure. This paper explores the effect of in-depth mobility patterns. Specifically, we study individuals\\' movement behavior, and quantify mobility on the basis of trip frequency, travel purpose and transportation mode. Our hybrid link prediction model is composed of two modules. The first module extracts mobility patterns, including travel purpose and mode, from raw trajectory data. The second module employs the extracted patterns for link prediction. We evaluate our method on two real data sets, GeoLife [15] and Reality Mining [5]. Experimental results show that our hybrid model significantly improves the accuracy of social link prediction, when comparing to primary topology-based solutions. Copyright 2014 ACM.

  11. Linking to the Future

    Science.gov (United States)

    Moore, John W.

    1999-09-01

    of JCE in the mail each month, and I expect you do too. I can glance at the cover to get an overview of an issue's content, and I usually am enticed inside by intriguing cover art. I can scan the table of contents to find articles I want to read, or I can just browse through the issue to see what looks interesting. Usually the editors have juxtaposed related articles so that I often find a small treasure trove. The printed Journal is quite portable and can be read in a car or airplane. It will last a long time, and until the paper deteriorates, I will never have a problem reading back issues. I have almost every issue from the first day I subscribed and have even added some older ones from collections of retired colleagues who no longer had shelf space for them. I certainly would not want to give up my printed copies, and I want to keep getting them. I find that JCE Online provides a different kind of resource that is equally valuable. It contains more information, and information that is more appropriate in electronic form. It links related ideas into a much more complex web of information than is possible in print. And it opens pathways to lots of information that is not part of JCE but resides elsewhere. Using this issue as an example, let's take a tour of what JCE Online can do. Point your Web browser to http://jchemed.chem.wisc.edu Click on Journal and then on Current Issue (unless September 1999 is no longer the current issue, in which case you will find it in Past Issues). In the table of contents, find the article "UV Catalysis, Cyanotype Photography, and Sunscreens". Click on the title. When the abstract appears, click on Full Text (PDF) to see the article, just as it appears on page 1199 in this issue. When you are prompted, enter the name and subscriber number from your address label. At the end of the article you will find that supplementary materials are available (including a procedure for testing sunscreens) and you can click on the link to view them

  12. [Hospitals as vital links].

    Science.gov (United States)

    Klink, A

    2013-01-01

    The reform of the system in 2006 aimed at reducing waiting lists in an efficient manner. Performance-linked funding and regulated competition did indeed lead to improved efficiency. The other side of the coin is overtreatment, and expensive and not infrequently damaging growth in volume. In order to control costs, three strategies have been determined: agreements with an annual cap on volume; (b) collaboration of regional health-care providers with the mission of improving results in health care (with profit-sharing if costs fall); and (c) fusions reducing the number of hospitals which reduces the burden of injuries (supply no longer creates its own demand). This article comments on these strategies. The author argues for a fourth approach: if the quality of health care improves, the number of complications will fall, overtreatment will decline and the outcome will be a decrease in burden of injuries. This requires the health care insurers to modify the way they manage their contracts and methods of payment, and stimulates competition based on quality.

  13. Generalized normal rulings and invariants of Legendrian solid torus links

    CERN Document Server

    Lavrov, Mikhail

    2011-01-01

    For Legendrian links in the 1-jet space of $S^1$ we show that the 1-graded ruling polynomial may be recovered from the Kauffman skein module. For such links a generalization of the notion of normal ruling is introduced. We show that the existence of such a generalized normal ruling is equivalent to sharpness of the Kauffman polynomial estimate for the Thurston-Bennequin number as well as to the existence of an ungraded augmentation of the Chekanov-Eliashberg DGA. Parallel results involving the HOMFLY-PT polynomial and 2-graded generalized normal rulings are established.

  14. Action semantics modulate action prediction.

    Science.gov (United States)

    Springer, Anne; Prinz, Wolfgang

    2010-11-01

    Previous studies have demonstrated that action prediction involves an internal action simulation that runs time-locked to the real action. The present study replicates and extends these findings by indicating a real-time simulation process (Graf et al., 2007), which can be differentiated from a similarity-based evaluation of internal action representations. Moreover, results showed that action semantics modulate action prediction accuracy. The semantic effect was specified by the processing of action verbs and concrete nouns (Experiment 1) and, more specifically, by the dynamics described by action verbs (Experiment 2) and the speed described by the verbs (e.g., "to catch" vs. "to grasp" vs. "to stretch"; Experiment 3). These results propose a linkage between action simulation and action semantics as two yet unrelated domains, a view that coincides with a recent notion of a close link between motor processes and the understanding of action language.

  15. Empowering pharmacoinformatics by linked life science data.

    Science.gov (United States)

    Goldmann, Daria; Zdrazil, Barbara; Digles, Daniela; Ecker, Gerhard F

    2016-11-09

    With the public availability of large data sources such as ChEMBLdb and the Open PHACTS Discovery Platform, retrieval of data sets for certain protein targets of interest with consistent assay conditions is no longer a time consuming process. Especially the use of workflow engines such as KNIME or Pipeline Pilot allows complex queries and enables to simultaneously search for several targets. Data can then directly be used as input to various ligand- and structure-based studies. In this contribution, using in-house projects on P-gp inhibition, transporter selectivity, and TRPV1 modulation we outline how the incorporation of linked life science data in the daily execution of projects allowed to expand our approaches from conventional Hansch analysis to complex, integrated multilayer models.

  16. Empowering pharmacoinformatics by linked life science data

    Science.gov (United States)

    Goldmann, Daria; Zdrazil, Barbara; Digles, Daniela; Ecker, Gerhard F.

    2016-11-01

    With the public availability of large data sources such as ChEMBLdb and the Open PHACTS Discovery Platform, retrieval of data sets for certain protein targets of interest with consistent assay conditions is no longer a time consuming process. Especially the use of workflow engines such as KNIME or Pipeline Pilot allows complex queries and enables to simultaneously search for several targets. Data can then directly be used as input to various ligand- and structure-based studies. In this contribution, using in-house projects on P-gp inhibition, transporter selectivity, and TRPV1 modulation we outline how the incorporation of linked life science data in the daily execution of projects allowed to expand our approaches from conventional Hansch analysis to complex, integrated multilayer models.

  17. Empowering pharmacoinformatics by linked life science data

    Science.gov (United States)

    Goldmann, Daria; Zdrazil, Barbara; Digles, Daniela; Ecker, Gerhard F.

    2017-03-01

    With the public availability of large data sources such as ChEMBLdb and the Open PHACTS Discovery Platform, retrieval of data sets for certain protein targets of interest with consistent assay conditions is no longer a time consuming process. Especially the use of workflow engines such as KNIME or Pipeline Pilot allows complex queries and enables to simultaneously search for several targets. Data can then directly be used as input to various ligand- and structure-based studies. In this contribution, using in-house projects on P-gp inhibition, transporter selectivity, and TRPV1 modulation we outline how the incorporation of linked life science data in the daily execution of projects allowed to expand our approaches from conventional Hansch analysis to complex, integrated multilayer models.

  18. A photovoltaic module

    OpenAIRE

    Krebs, Frederik C.; Sommer-Larsen, Peter

    2013-01-01

    The present invention relates to a photovoltaic module comprising a carrier substrate, said carrier substrate carrying a purely printed structure comprising printed positive and negative module terminals, a plurality of printed photovoltaic cell units each comprising one or more printed photovoltaic cells, wherein the plurality of printed photovoltaic cell units are electrically connected in series between the positive and the negative module terminals such that any two neighbouring photovolt...

  19. Investigating Quantum Modulation States

    Science.gov (United States)

    2016-03-01

    3. DATES COVERED (From - To) OCT 2012 – SEP 2015 4. TITLE AND SUBTITLE INVESTIGATING QUANTUM MODULATION STATES 5a. CONTRACT NUMBER IN-HOUSE 5b...Coherent states are the most classical of quantum states. Generation and detection of their polarization and phase modulations are well...stream cipher maps message bits onto random blocks of bits producing modulated states that are intrinsically noisy. The ciphertext so generated is

  20. Protective link for superconducting coil

    Science.gov (United States)

    Umans, Stephen D.

    2009-12-08

    A superconducting coil system includes a superconducting coil and a protective link of superconducting material coupled to the superconducting coil. A rotating machine includes first and second coils and a protective link of superconducting material. The second coil is operable to rotate with respect to the first coil. One of the first and second coils is a superconducting coil. The protective link is coupled to the superconducting coil.

  1. Using ATM over SATCOM links

    Science.gov (United States)

    Comparetto, Gary M.

    1995-01-01

    The Asynchronous Transfer Mode (ATM) protocol is studied from the standpoint of determining what limitations, if any, exist in using it over satellite links. It is concluded that, while there is nothing intrinsic about ATM that would generally preclude its use over satellite links, there are, however, several intrinsic characteristics of satellite links, as well as some satellite system configuration-specific issues, that must be taken into account.

  2. From regular modules to von Neumann regular rings via coordinatization

    Directory of Open Access Journals (Sweden)

    Leonard Daus

    2014-07-01

    Full Text Available In this paper we establish a very close link (in terms of von Neu- mann's coordinatization between regular modules introduced by Zel- manowitz, on one hand, and von Neumann regular rings, on the other hand: we prove that the lattice L^{fg}(M of all finitely generated submodules of a finitely generated regular module M, over an arbitrary ring, can be coordinatized as the lattice of all principal right ideals of some von Neumann regular ring S.

  3. Modulation of the Intracortical LFP during Action Execution and Observation

    OpenAIRE

    2015-01-01

    The activity of mirror neurons in macaque ventral premotor cortex (PMv) and primary motor cortex (M1) is modulated by the observation of another's movements. This modulation could underpin well documented changes in EEG/MEG activity indicating the existence of a mirror neuron system in humans. Because the local field potential (LFP) represents an important link between macaque single neuron and human noninvasive studies, we focused on mirror properties of intracortical LFPs recorded in the PM...

  4. Model theory and modules

    CERN Document Server

    Prest, M

    1988-01-01

    In recent years the interplay between model theory and other branches of mathematics has led to many deep and intriguing results. In this, the first book on the topic, the theme is the interplay between model theory and the theory of modules. The book is intended to be a self-contained introduction to the subject and introduces the requisite model theory and module theory as it is needed. Dr Prest develops the basic ideas concerning what can be said about modules using the information which may be expressed in a first-order language. Later chapters discuss stability-theoretic aspects of module

  5. Delphi Accounts Receivable Module -

    Data.gov (United States)

    Department of Transportation — Delphi accounts receivable module contains the following data elements, but are not limited to customer information, cash receipts, line of accounting details, bill...

  6. THERMOELECTRIC POWER MODULES.

    Science.gov (United States)

    MODULES (ELECTRONICS), GENERATORS, THERMOELECTRICITY, PERFORMANCE(ENGINEERING), TABLES(DATA), HEAT, ALUMINUM, WEIGHT, SEMICONDUCTORS, SILICON, GERMANIUM, MEASUREMENT, VOLTAGE, ELECTRICAL RESISTANCE, POWER, TEMPERATURE, TIME.

  7. "Conjectural" links in complex networks

    Science.gov (United States)

    Snarskii, A. A.; Zorinets, D. I.; Lande, D. V.

    2016-11-01

    This paper introduces the concept of Conjectural Link for Complex Networks, in particular, social networks. Conjectural Link we understand as an implicit link, not available in the network, but supposed to be present, based on the characteristics of its topology. It is possible, for example, when in the formal description of the network some connections are skipped due to errors, deliberately hidden or withdrawn (e.g. in the case of partial destruction of the network). Introduced a parameter that allows ranking the Conjectural Link. The more this parameter - the more likely that this connection should be present in the network. This paper presents a method of recovery of partially destroyed Complex Networks using Conjectural Links finding. Presented two methods of finding the node pairs that are not linked directly to one another, but have a great possibility of Conjectural Link communication among themselves: a method based on the determination of the resistance between two nodes, and method based on the computation of the lengths of routes between two nodes. Several examples of real networks are reviewed and performed a comparison to know network links prediction methods, not intended to find the missing links in already formed networks.

  8. PACRG, a protein linked to ciliary motility, mediates cellular signaling.

    OpenAIRE

    Loucks, Catrina M.; Bialas, Nathan J.; Dekkers, Martijn; Walker, Denise S.; Grundy, Laura J.; Li, Chunmei; Inglis, P. Nick; Kida, Katarzyna; Schafer, William R; Blacque, Oliver E; Jansen, Gert; Michel R Leroux

    2016-01-01

    Cilia are microtubule-based organelles that project from nearly all mammalian cell types. Motile cilia generate fluid flow, whereas nonmotile (primary) cilia are required for sensory physiology and modulate various signal transduction pathways. Here we investigate the nonmotile ciliary signaling roles of parkin coregulated gene (PACRG), a protein linked to ciliary motility. PACRG is associated with the protofilament ribbon, a structure believed to dictate the regular arrangement of motility-a...

  9. PACRG, a protein linked to ciliary motility, mediates cellular signaling

    OpenAIRE

    Loucks, Catrina M.; Bialas, Nathan J.; Dekkers, Martijn P. J.; Walker, Denise S.; Grundy, Laura J.; Li, Chunmei; Inglis, P. Nick; Kida, Katarzyna; Schafer, William R; Blacque, Oliver E; Jansen, Gert; Michel R Leroux

    2016-01-01

    Cilia are microtubule-based organelles that project from nearly all mammalian cell types. Motile cilia generate fluid flow, whereas nonmotile (primary) cilia are required for sensory physiology and modulate various signal transduction pathways. Here we investigate the nonmotile ciliary signaling roles of parkin coregulated gene (PACRG), a protein linked to ciliary motility. PACRG is associated with the protofilament ribbon, a structure believed to dictate the regular arrangement of motility-a...

  10. Asymmetrical Modulation for Uplink Communication in Cooperative Networks

    DEFF Research Database (Denmark)

    Zhang, Qi; Fitzek, Frank H.P.; Iversen, Villy Bæk

    2008-01-01

    In this paper a spectrum efficient uplink communication method for cooperative wireless networks is presented. In cellular controlled peer to peer (CCP2P) cooperative wireless networks the mobile device is logically connected over cellular links with the base station and simultaneously over short......-range links with neighboring mobile devices to form cooperative clusters. So far the physical communication over cellular links and over short-range links are separated in time or in frequency. Beyond this state of the art, we exploit a method, referred to as asymmetrical modulation, where a mobile device...... information, the neighboring devices are getting the fine grained information reading between the lines. Our analytical analysis and simulation results show that asymmetrical modulation can improve the spectrum efficiency and reduce the data queuing delay with neither degrading the symbol error rate...

  11. Link Clustering with Extended Link Similarity and EQ Evaluation Division.

    Directory of Open Access Journals (Sweden)

    Lan Huang

    Full Text Available Link Clustering (LC is a relatively new method for detecting overlapping communities in networks. The basic principle of LC is to derive a transform matrix whose elements are composed of the link similarity of neighbor links based on the Jaccard distance calculation; then it applies hierarchical clustering to the transform matrix and uses a measure of partition density on the resulting dendrogram to determine the cut level for best community detection. However, the original link clustering method does not consider the link similarity of non-neighbor links, and the partition density tends to divide the communities into many small communities. In this paper, an Extended Link Clustering method (ELC for overlapping community detection is proposed. The improved method employs a new link similarity, Extended Link Similarity (ELS, to produce a denser transform matrix, and uses the maximum value of EQ (an extended measure of quality of modularity as a means to optimally cut the dendrogram for better partitioning of the original network space. Since ELS uses more link information, the resulting transform matrix provides a superior basis for clustering and analysis. Further, using the EQ value to find the best level for the hierarchical clustering dendrogram division, we obtain communities that are more sensible and reasonable than the ones obtained by the partition density evaluation. Experimentation on five real-world networks and artificially-generated networks shows that the ELC method achieves higher EQ and In-group Proportion (IGP values. Additionally, communities are more realistic than those generated by either of the original LC method or the classical CPM method.

  12. A cannabinoid link between mitochondria and memory.

    Science.gov (United States)

    Hebert-Chatelain, Etienne; Desprez, Tifany; Serrat, Román; Bellocchio, Luigi; Soria-Gomez, Edgar; Busquets-Garcia, Arnau; Pagano Zottola, Antonio Christian; Delamarre, Anna; Cannich, Astrid; Vincent, Peggy; Varilh, Marjorie; Robin, Laurie M; Terral, Geoffrey; García-Fernández, M Dolores; Colavita, Michelangelo; Mazier, Wilfrid; Drago, Filippo; Puente, Nagore; Reguero, Leire; Elezgarai, Izaskun; Dupuy, Jean-William; Cota, Daniela; Lopez-Rodriguez, Maria-Luz; Barreda-Gómez, Gabriel; Massa, Federico; Grandes, Pedro; Bénard, Giovanni; Marsicano, Giovanni

    2016-11-24

    Cellular activity in the brain depends on the high energetic support provided by mitochondria, the cell organelles which use energy sources to generate ATP. Acute cannabinoid intoxication induces amnesia in humans and animals, and the activation of type-1 cannabinoid receptors present at brain mitochondria membranes (mtCB1) can directly alter mitochondrial energetic activity. Although the pathological impact of chronic mitochondrial dysfunctions in the brain is well established, the involvement of acute modulation of mitochondrial activity in high brain functions, including learning and memory, is unknown. Here, we show that acute cannabinoid-induced memory impairment in mice requires activation of hippocampal mtCB1 receptors. Genetic exclusion of CB1 receptors from hippocampal mitochondria prevents cannabinoid-induced reduction of mitochondrial mobility, synaptic transmission and memory formation. mtCB1 receptors signal through intra-mitochondrial Gαi protein activation and consequent inhibition of soluble-adenylyl cyclase (sAC). The resulting inhibition of protein kinase A (PKA)-dependent phosphorylation of specific subunits of the mitochondrial electron transport system eventually leads to decreased cellular respiration. Hippocampal inhibition of sAC activity or manipulation of intra-mitochondrial PKA signalling or phosphorylation of the Complex I subunit NDUFS2 inhibit bioenergetic and amnesic effects of cannabinoids. Thus, the G protein-coupled mtCB1 receptors regulate memory processes via modulation of mitochondrial energy metabolism. By directly linking mitochondrial activity to memory formation, these data reveal that bioenergetic processes are primary acute regulators of cognitive functions.

  13. Produce and Consume Linked Data with Drupal!

    Science.gov (United States)

    Corlosquet, Stéphane; Delbru, Renaud; Clark, Tim; Polleres, Axel; Decker, Stefan

    Currently a large number of Web sites are driven by Content Management Systems (CMS) which manage textual and multimedia content but also - inherently - carry valuable information about a site's structure and content model. Exposing this structured information to the Web of Data has so far required considerable expertise in RDF and OWL modelling and additional programming effort. In this paper we tackle one of the most popular CMS: Drupal. We enable site administrators to export their site content model and data to the Web of Data without requiring extensive knowledge on Semantic Web technologies. Our modules create RDFa annotations and - optionally - a SPARQL endpoint for any Drupal site out of the box. Likewise, we add the means to map the site data to existing ontologies on the Web with a search interface to find commonly used ontology terms. We also allow a Drupal site administrator to include existing RDF data from remote SPARQL endpoints on the Web in the site. When brought together, these features allow networked RDF Drupal sites that reuse and enrich Linked Data. We finally discuss the adoption of our modules and report on a use case in the biomedical field and the current status of its deployment.

  14. Capacity-Approaching Superposition Coding for Optical Fiber Links

    DEFF Research Database (Denmark)

    Estaran Tolosa, Jose Manuel; Zibar, Darko; Tafur Monroy, Idelfonso

    2014-01-01

    We report on the first experimental demonstration of superposition coded modulation (SCM) for polarization-multiplexed coherent-detection optical fiber links. The proposed coded modulation scheme is combined with phase-shifted bit-to-symbol mapping (PSM) in order to achieve geometric and passive...... shaping of the signal's waveform. The output constellations in SCM-PSM exhibit nonbijective quasi-Gaussian statistical distributions that asymptotically reach the Shannon capacity limit, showing up to 0.7 dB sensitivity improvement for 256-ary SCM-PSM with respect to 256-ary quadrature amplitude...... modulation (QAM). The characteristic wave formation based on superposition of antipodal symbols and the lack of need for additional encoders for signal shaping, greatly reduces the transmitter and receiver processing complexity in comparison to conventional alternatives. Single-level coding strategy (SL-SCM...

  15. Links between circadian rhythms and psychiatric disease

    Directory of Open Access Journals (Sweden)

    Ilia N Karatsoreos

    2014-05-01

    Full Text Available Determining the cause of psychiatric disorders is a goal of modern neuroscience, and will hopefully lead to the discovery of treatments to either prevent or alleviate the suffering caused by these diseases. One roadblock to attaining this goal is the realization that neuropsychiatric diseases are rarely due to a single gene polymorphism, environmental exposure, or developmental insult. Rather, it is a complex interaction between these various influences that likely leads to the development of clinically relevant syndromes. Our lab is exploring the links between environmental exposures and neurobehavioral function by investigating how disruption of the circadian (daily clock alters the structure and function of neural circuits, with the hypothesis that disrupting this crucial homeostatic system can directly contribute to altered vulnerability of the organism to other factors that interact to produce psychiatric illness. This review explores some historical and more recent findings that link disrupted circadian clocks to neuropsychiatric disorders, particularly depression, mania, and schizophrenia. We take a comparative approach by exploring the effects observed in human populations, as well as some experimental models used in the laboratory to unravel mechanistic and causal relationships between disruption of the circadian clock and behavioral abnormalities. This is a rich area of research that we predict will contribute greatly to our understanding of how genes, environment, and development interact to modulate an individual’s vulnerability to psychiatric disorders.

  16. Game Changer: Linked Learning Detroit

    Science.gov (United States)

    ConnectEd: The California Center for College and Career, 2016

    2016-01-01

    JP Morgan Chase joins the Skillman Foundation, the Ford Foundation, and the Ford Motor Company Fund, whose grants total $7 million and will connect 10,000 Detroit high school students to career education and work experiences over the next three years through Linked Learning Detroit. Learn about Linked Learning Detroit through interviews with…

  17. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... NIDA : Facebook LinkedIn Twitter YouTube Flickr RSS Menu Home Drugs of Abuse Commonly Abused Drugs Charts Emerging ... Badges Other Resources Strategic Plan Search Share Print Home » News & Events » Public Education Projects » Learn the Link - ...

  18. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... Plan Search Share Print Home » News & Events » Public Education Projects » Learn the Link - Drugs and HIV Learn the Link - Drugs and HIV Email Facebook Twitter 2005 –Ongoing Behaviors associated with drug abuse are among the main factors in the spread of HIV infection in the ...

  19. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... Plus Facebook LinkedIn Twitter YouTube Flickr RSS Menu Home Drugs of Abuse Commonly Abused Drugs Charts Emerging ... Badges Other Resources Strategic Plan Search Share Print Home » News & Events » Public Education Projects » Learn the Link - ...

  20. Optimizing pointer linked data structures

    NARCIS (Netherlands)

    Holm, Carl Wilhelm Mattias

    2013-01-01

    The thesis explores different ways of optimizing pointer linked data structures, and especially restructuring them. The mechanisms are based on compiler technology, theory, computer languages and hardware architecture that are capable of optimizing the memory layout of complex pointer linked data st

  1. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... link between drug abuse and HIV. http://1.usa.gov/1z20ww6 How many of us think about ... can’t ignore. Learn the Link: http://1.usa.gov/1uSUAI3 Think you’re not at risk? ...

  2. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... Parents & Educators Children & Teens Search Connect with NIDA : Facebook LinkedIn Twitter YouTube Flickr RSS Menu Home Drugs ... HIV Learn the Link - Drugs and HIV Email Facebook Twitter 2005 –Ongoing Behaviors associated with drug abuse ...

  3. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... the Link campaign. This campaign shows teens and young adults that non-injection drug use and alcohol use can lead to poor decision making, which ... message to America's youth that using drugs and alcohol even once can have ... in the lives of young people-with the Learn the Link message. Campaign ...

  4. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... in your posts! Learn the link between drug abuse and HIV. http://1.usa.gov/1z20ww6 How many of us ... not at risk? Learn the link between drug abuse and HIV. http://1.usa.gov/VF4sGf [Tag friends, colleagues, partners] ...

  5. [Sex-linked juvenile retinoschisis].

    Science.gov (United States)

    François, P; Turut, P; Soltysik, C; Hache, J C

    1976-02-01

    About 13 observations of sexe linked juvenile retinoschisis, the authors describe the ophthalmoscopic, fluorographic and functional aspects of the disease whose caracteristics are:--its sexe linked recessive heredity; --its clinical characterestics associating: a microcystic macular degeneration, peripheral retinal lesions, vitreous body alterations, --an electroretinogram of the negative type.

  6. Linking Information for Mobile Use

    Science.gov (United States)

    2007-09-01

    interface after reading the XML. .. 30 Figure 8. Display of an item’s content with linked items one click away. ........... 31 Figure 9. Movement...related, but the user has not viewed recently. Figure 8. Display of an item’s content with linked items one click away. Figure 9 shows the

  7. Amsterdam Museum Linked Open Data

    NARCIS (Netherlands)

    Boer, V. de; Wielemaker, J.; Gent, J. van; O'Connell, J.; Oosterbroek, M; Hildebrand, M.; Isaac, A.; Ossenbruggen, J.R. van; Schreiber, G.

    2013-01-01

    In this document we describe the Amsterdam Museum Linked Open Data set. The dataset is a five-star Linked Data representation and comprises the entire collection of the Amsterdam Museum consisting of more than 70,000 object descriptions. Furthermore, the institution's thesaurus and person authority

  8. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... Children & Teens Search Connect with NIDA : Google Plus Facebook LinkedIn Twitter YouTube Flickr RSS Menu Home Drugs ... HIV Learn the Link - Drugs and HIV Email Facebook Twitter 2005 –Ongoing Behaviors associated with drug abuse ...

  9. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... site. Please link these banners back to this site at: http://www.drugabuse.gov/news-events/public-education-projects/learn-link-drugs-hiv . 120x90 460x80 486x60 Social Media Send the message to young people and ...

  10. Parabolic Dish Stirling Module

    Science.gov (United States)

    Washom, B.

    1984-01-01

    The design, manufacture, and assembly of a commercially designed parabolic dish Stirling 25 kWe module is examined. The cost, expected performance, design uniquenesses, and future commercial potential of this module, which is regarded as the most technically advanced in the parabolic dish industry is discussed.

  11. Synthetic Space Vector Modulation

    Science.gov (United States)

    2013-06-01

    Modulation RF Radio Frequency SVM Space Vector Modulation VCO Voltage Controlled Oscillator VSI Voltage Source Inverter xvi THIS PAGE...examining the literature, an NE566 voltage controlled oscillator ( VCO ) chip as seen in Figure 10 was used to design a circuit that produced the

  12. Cosmetology. Computerized Learning Modules.

    Science.gov (United States)

    Finnerty, Kathy, Ed.

    Intended to help reading-limited students meet course objectives, these 11 modules are based on instructional materials in cosmetology that have a higher readability equivalent. Modules cover bacteriology, chemical waving, scalp and hair massage, chemistry, hair shaping, hairstyling, chemical hair relaxing, hair coloring, skin and scalp,…

  13. The Structure of Modules

    Institute of Scientific and Technical Information of China (English)

    陈焕艮; 佟文廷

    1994-01-01

    In this paper,we introduce two concepts:projective radical and semi-reflexive radical of a module,and establish some elementary relations among subprojective,semi-reflexive and torsion-free modules Using these properties,ws give classifications of some rings.

  14. Nullification of knots and links

    CERN Document Server

    Diao, Yuanan; Montemayor, Anthony

    2011-01-01

    In this paper, we study a geometric/topological measure of knots and links called the nullification number. The nullification of knots/links is believed to be biologically relevant. For example, in DNA topology, one can intuitively regard it as a way to measure how easily a knotted circular DNA can unknot itself through recombination of its DNA strands. It turns out that there are several different ways to define such a number. These definitions lead to nullification numbers that are related, but different. Our aim is to explore the mathematical properties of these nullification numbers. First, we give specific examples to show that the nullification numbers we defined are different. We provide detailed analysis of the nullification numbers for the well known 2-bridge knots and links. We also explore the relationships among the three nullification numbers, as well as their relationships with other knot invariants. Finally, we study a special class of links, namely those links whose general nullification numbe...

  15. Link adaptation algorithm for distributed coded transmissions in cooperative OFDMA systems

    DEFF Research Database (Denmark)

    Varga, Mihaly; Badiu, Mihai Alin; Bota, Vasile

    2015-01-01

    This paper proposes a link adaptation algorithm for cooperative transmissions in the down-link connection of an OFDMA-based wireless system. The algorithm aims at maximizing the spectral efficiency of a relay-aided communication link, while satisfying the block error rate constraints at both...... the relay and the destination nodes. The optimal solution would be to perform an exhaustive search over a high-dimensional space determined by all possible combinations of modulations, code rates and information block lengths on the individual channels of the cooperative link; clearly, such an approach has...... an intractable complexity. Our solution is to use a link performance prediction method and a trellis diagram representation such that the resulting algorithm outputs the link configuration that conveys as many information bits as possible and also fulfilling the block error rate constraints. The proposed link...

  16. Joint Relay Selection and Link Adaptation for Distributed Beamforming in Regenerative Cooperative Networks

    CERN Document Server

    Yang, Wei; Wu, Gang; Wang, Haifeng

    2010-01-01

    Relay selection enhances the performance of the cooperative networks by selecting the links with higher capacity. Meanwhile link adaptation improves the spectral efficiency of wireless data-centric networks through adapting the modulation and coding schemes (MCS) to the current link condition. In this paper, relay selection is combined with link adaptation for distributed beamforming in a two-hop regenerative cooperative system. A novel signaling mechanism and related optimal algorithms are proposed for joint relay selection and link adaptation. In the proposed scheme, there is no need to feedback the relay selection results to each relay. Instead, by broadcasting the link adaptation results from the destination, each relay will automatically understand whether it is selected or not. The lower and upper bounds of the throughput of the proposed scheme are derived. The analysis and simulation results indicate that the proposed scheme provides synergistic gains compared to the pure relay selection and link adapt...

  17. Solar energy modulator

    Science.gov (United States)

    Hale, R. R. (Inventor); Mcdougal, A. R.

    1984-01-01

    A module is described with a receiver having a solar energy acceptance opening and supported by a mounting ring along the optic axis of a parabolic mirror in coaxial alignment for receiving solar energy from the mirror, and a solar flux modulator plate for varying the quantity of solar energy flux received by the acceptance opening of the module. The modulator plate is characterized by an annular, plate-like body, the internal diameter of which is equal to or slightly greater than the diameter of the solar energy acceptance opening of the receiver. Slave cylinders are connected to the modulator plate for supporting the plate for axial displacement along the axis of the mirror, therby shading the opening with respect to solar energy flux reflected from the surface of the mirror to the solar energy acceptance opening.

  18. 5 GHz 200 Mbit/s radio over polymer fiber link with envelope detection at 650 nm wavelength

    DEFF Research Database (Denmark)

    Caballero Jambrina, Antonio; Jensen, Jesper Bevensee; Yu, Xianbin;

    2009-01-01

    All-optical envelope detection of a 5 GHz 200 Mbit/s modulated RF signal and error free transmission over 50 m POF link is achieved by using a 650 nm RCLED.......All-optical envelope detection of a 5 GHz 200 Mbit/s modulated RF signal and error free transmission over 50 m POF link is achieved by using a 650 nm RCLED....

  19. Feasibility analysis of WDM links for radar applications

    Directory of Open Access Journals (Sweden)

    D. Meena

    2015-03-01

    Full Text Available Active phased array antennas enhances the performance of modern radars by using multiple low power transmit/receive modules in place of a high power transmitter in conventional radars. Fully distributed phased array radars demand the distribution of various signals in radio frequency (RF and digital domain for real time operation. This is normally achieved through complex and bulky coaxial distribution networks. In this work, we intend to tap the inherent advantages of fiber links with wavelength division multiplexed (WDM technology and a feasibility study to adapt these links for radar applications is carried out. This is done by analysing various parameters like amplitude, delay, frequency and phase variation response of various radar waveforms over WDM links. This also includes performance evaluation of non-linear frequency modulation (NLFM signals, known for better signal to noise ratio (SNR to specific side lobe levels. NLFM waveforms are further analysed using pulse compression (PC technique. Link evaluation is also carried out using a standard simulation environment and is then experimentally verified with other waveforms like RF continuous wave (CW, pulsed RF and digital signals. Synchronization signals are generated from this variable duty cycle digital signals during real time radar operation. During evaluation of digital signals, variable transient effects for different duty cycles are observed from an amplifier configuration. A suppression method is proposed to eliminate this transient effects. Further, the link delay response is investigated using different lengths of fiber spools. It can be inferred from the experimental results that WDM links are capable of handling various signals significant to radar applications.

  20. On Modules Whose Singular Subgenerated Modules Are Weakly Injective

    Institute of Scientific and Technical Information of China (English)

    S. Dhompongsa; J. Sanwong; S.Plubtieng; H.Tansee

    2001-01-01

    Rings over which every singular right module is injective (briefly,right SI-rings) were introduced and investigated by Goodearl. Weakly injective modules, as a generalization of injective modules, were introduced by Jain and modules are weakly injective, which we call SwI-rings. This concept is extended to SwI-modules, i.e., modules whose singular subgenerated modules are weakly injective. Several characterizations and properties of SwI-rings and SwI-modules are obtained which generalize some earlier known results on SI-rings and weakly semisimple rings.

  1. Photovoltaic module and interlocked stack of photovoltaic modules

    Science.gov (United States)

    Wares, Brian S.

    2014-09-02

    One embodiment relates to an arrangement of photovoltaic modules configured for transportation. The arrangement includes a plurality of photovoltaic modules, each photovoltaic module including a frame. A plurality of individual male alignment features and a plurality of individual female alignment features are included on each frame. Adjacent photovoltaic modules are interlocked by multiple individual male alignment features on a first module of the adjacent photovoltaic modules fitting into and being surrounded by corresponding individual female alignment features on a second module of the adjacent photovoltaic modules. Other embodiments, features and aspects are also disclosed.

  2. Essentially normal Hilbert modules and Khomology Ⅲ: Homogenous quotient modules of Hardy modules on the bidisk

    Institute of Scientific and Technical Information of China (English)

    Kun-yu GUO; Peng-hui WANG

    2007-01-01

    In this paper, we study the homogenous quotient modules of the Hardy module on the bidisk. The essential normality of the homogenous quotient modules is completely characterized. We also describe the essential spectrum for a general quotient module. The paper also considers K-homology invariant defined in the case of the homogenous quotient modules on the bidisk.

  3. Demonstration of 20-Gbit/s high-speed Bessel beam encoding/decoding link with adaptive turbulence compensation.

    Science.gov (United States)

    Chen, Shi; Li, Shuhui; Zhao, Yifan; Liu, Jun; Zhu, Long; Wang, Andong; Du, Jing; Shen, Li; Wang, Jian

    2016-10-15

    By mapping traditional amplitude modulation to spatial modulation and employing adaptive optics compensation technique, we propose and experimentally demonstrate a high-speed Bessel beam encoding/decoding free-space optical link through atmospheric turbulence. The Bessel beam encoding/decoding speed is not limited by the conventional slow switching response of a spatial light modulator (SLM) but is fully determined by the modulation rate of an intensity modulator, which easily supports tens of gigabits per second modulation and resultant encoding/decoding. We use an SLM loaded with a pseudorandom phase mask to emulate atmospheric turbulence in the laboratory environment. An adaptive optics closed loop is used to sense the phase distortion of an extra probe Gaussian beam and then compensate the distorted Bessel beams. A 20-Gbit/s Bessel beam encoding/decoding link with adaptive turbulence compensation is demonstrated in the experiment, showing favorable operation performance.

  4. Integrating Linked Data into Discovery

    Directory of Open Access Journals (Sweden)

    Götz Hatop

    2013-07-01

    Full Text Available Although the Linked Data paradigm has evolved from a research idea to a practical approach for publishing structured data on the web, the performance gap between currently available RDF data stores and the somewhat older search technologies could not be closed. The combination of Linked Data with a search engine can help to improve ad-hoc retrieval. This article presents and documents the process of building a search index for the Solr search engine from bibliographic records published as linked open data.

  5. Carrierless N-Dimensional Modulation Format for Multiple Service Differentiation in Optical In-home Networks

    DEFF Research Database (Denmark)

    Caballero Jambrina, Antonio; Pham, Tien Thang; Jensen, Jesper Bevensee

    2011-01-01

    We propose and experimentally demonstrate the use of carrierless N-dimensional modulation for multiple services distribution in an experiment for 8 Gbitls, VeSEL based, 1 km MMF link using baseband electronics.......We propose and experimentally demonstrate the use of carrierless N-dimensional modulation for multiple services distribution in an experiment for 8 Gbitls, VeSEL based, 1 km MMF link using baseband electronics....

  6. Experimental Demonstration of Capacity-Achieving Phase-Shifted Superposition Modulation

    DEFF Research Database (Denmark)

    Estaran Tolosa, Jose Manuel; Zibar, Darko; Caballero Jambrina, Antonio

    2013-01-01

    We report on the first experimental demonstration of phase-shifted superposition modulation (PSM) for optical links. Successful demodulation and decoding is obtained after 240 km transmission for 16-, 32- and 64-PSM.......We report on the first experimental demonstration of phase-shifted superposition modulation (PSM) for optical links. Successful demodulation and decoding is obtained after 240 km transmission for 16-, 32- and 64-PSM....

  7. Solar cell module. Taiyo denchi module

    Energy Technology Data Exchange (ETDEWEB)

    Nakano, Akihiko; Matsumoto, Hitoshi; Komatsu, Yasumitsu; Shirai, Sadaharu.

    1989-09-29

    In the solar cell module of this invention, such junctions as CdS/CdTe or CdS/CuInSe {sub 2} are contained as a photoelectromotive force part coexists with air in a closed space which consists of glass, metal parts and a bonding resin layer; the photoelectromotive force part is coated either with a fluorine resin or a silicone resin. The fluorine resin contains a fundamental skeleton of an alternative copolymer of fluoroolefin and a hydrocarbon-based vinyl monomer; the silicone resin has three types, i.e., addition-reacted, condensated or UV-curing type, and the released oxygen is sealed in the closed space. The resin layer which adheres the glass and the metal plate is a thermoplastic resin which is polyethylene modified by copolymerization of acid anhydride. By this, the reliability of the solar cell module was enhanced. 3 figs.

  8. Optical modulator including grapene

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Ming; Yin, Xiaobo; Zhang, Xiang

    2016-06-07

    The present invention provides for a one or more layer graphene optical modulator. In a first exemplary embodiment the optical modulator includes an optical waveguide, a nanoscale oxide spacer adjacent to a working region of the waveguide, and a monolayer graphene sheet adjacent to the spacer. In a second exemplary embodiment, the optical modulator includes at least one pair of active media, where the pair includes an oxide spacer, a first monolayer graphene sheet adjacent to a first side of the spacer, and a second monolayer graphene sheet adjacent to a second side of the spacer, and at least one optical waveguide adjacent to the pair.

  9. Analytic Hilbert modules

    CERN Document Server

    Chen, Xiaoman

    2003-01-01

    The seminal 1989 work of Douglas and Paulsen on the theory of analytic Hilbert modules precipitated a number of major research efforts. This in turn led to some intriguing and valuable results, particularly in the areas of operator theory and functional analysis. With the field now beginning to blossom, the time has come to collect those results under one cover. Written by two of the most active and often-cited researchers in the field, Analytic Hilbert Modules reports on the progress made by the authors and others, including the characteristic space theory, rigidity, the equivalence problem, the Arveson modules, extension theory, and reproducing Hilbert spaces on n-dimensional complex space.

  10. The ANTARES Optical Module

    CERN Document Server

    Amram, P; Anvar, S; Ardellier-Desages, F E; Aslanides, Elie; Aubert, Jean-Jacques; Azoulay, R; Bailey, D; Basa, S; Battaglieri, M; Bellotti, R; Benhammou, Ya; Bernard, F; Berthier, R; Bertin, V; Billault, M; Blaes, R; Bland, R W; Blondeau, F; De Botton, N R; Boulesteix, J; Brooks, B; Brunner, J; Cafagna, F; Calzas, A; Capone, A; Caponetto, L; Cârloganu, C; Carmona, E; Carr, J; Carton, P H; Cartwright, S L; Cassol, F; Cecchini, S; Ciacio, F; Circella, M; Compere, C; Cooper, S; Coyle, P; Croquette, J; Cuneo, S; Danilov, M; Van Dantzig, R; De Marzo, C; De Vita, R; Deck, P; Destelle, J J; Dispau, G; Drougou, J F; Druillole, F; Engelen, J; Feinstein, F; Festy, D; Fopma, J; Gallone, J M; Giacomelli, G; Goret, P; Gosset, L G; Gournay, J F; Heijboer, A; Hernández-Rey, J J; Herrouin, G; Hubbard, John R; Jacquet, M; De Jong, M; Karolak, M; Kooijman, P M; Kouchner, A; Kudryavtsev, V A; Lachartre, D; Lafoux, H; Lamare, P; Languillat, J C; Laubier, L; Laugier, J P; Le Guen, Y; Le Provost, H; Le Van-Suu, A; Lemoine, L; Lo Nigro, L; Lo Presti, D; Loucatos, Sotirios S; Louis, F; Lyashuk, V I; Magnier, P; Marcelin, M; Margiotta, A; Massol, A; Masullo, R; Mazéas, F; Mazeau, B; Mazure, A; McMillan, J E; Michel, J L; Migneco, E; Millot, C; Mols, P; Montanet, François; Montaruli, T; Morel, J P; Moscoso, L; Navas, S; Nezri, E; Nooren, G J L; Oberski, J; Olivetto, C; Oppelt-pohl, A; Palanque-Delabrouille, Nathalie; Payre, P; Perrin, P; Petruccetti, M; Petta, P; Piattelli, P; Poinsignon, J; Popa, V; Potheau, R; Queinec, Y; Racca, C; Raia, G; Randazzo, N; Rethore, F; Riccobene, G; Ricol, J S; Ripani, M; Roca-Blay, V; Rolin, J F; Rostovtsev, A A; Russo, G V; Sacquin, Yu; Salusti, E; Schuller, J P; Schuster, W; Soirat, J P; Suvorova, O; Spooner, N J C; Spurio, M; Stolarczyk, T; Stubert, D; Taiuti, M; Tao, Charling; Tayalati, Y; Thompson, L F; Tilav, S; Triay, R; Valente, V; Varlamov, I; Vaudaine, G; Vernin, P; De Witt-Huberts, P K A; De Wolf, E; Zakharov, V; Zavatarelli, S; De Dios-Zornoza-Gomez, Juan; Zúñiga, J

    2002-01-01

    The ANTARES collaboration is building a deep sea neutrino telescope in the Mediterranean Sea. This detector will cover a sensitive area of typically 0.1 km-squared and will be equipped with about 1000 optical modules. Each of these optical modules consists of a large area photomultiplier and its associated electronics housed in a pressure resistant glass sphere. The design of the ANTARES optical module, which is a key element of the detector, has been finalized following extensive R & D studies and is reviewed here in detail.

  11. The ANTARES optical module

    Energy Technology Data Exchange (ETDEWEB)

    Amram, P.; Anghinolfi, M.; Anvar, S.; Ardellier-Desages, F.E.; Aslanides, E.; Aubert, J.-J.; Azoulay, R.; Bailey, D.; Basa, S.; Battaglieri, M.; Bellotti, R.; Benhammou, Y.; Bernard, F.; Berthier, R.; Bertin, V.; Billault, M.; Blaes, R.; Bland, R.W.; Blondeau, F.; Botton, N. de; Boulesteix, J.; Brooks, C.B.; Brunner, J.; Cafagna, F.; Calzas, A.; Capone, A.; Caponetto, L.; Carloganu, C.; Carmona, E.; Carr, J.; Carton, P.-H.; Cartwright, S.L.; Cassol, F.; Cecchini, S.; Ciacio, F.; Circella, M.; Compere, C.; Cooper, S.; Coyle, P.; Croquette, J.; Cuneo, S.; Danilov, M.; Dantzig, R. van; De Marzo, C.; DeVita, R.; Deck, P.; Destelle, J.-J.; Dispau, G.; Drougou, J.F.; Druillole, F.; Engelen, J.; Feinstein, F.; Festy, D.; Fopma, J.; Gallone, J.-M.; Giacomelli, G.; Goret, P.; Gosset, L.; Gournay, J.-F.; Heijboer, A.; Hernandez-Rey, J.J.; Herrouin, G.; Hubbard, J.R.; Jaquet, M.; Jong, M. de; Karolak, M.; Kooijman, P.; Kouchner, A.; Kudryavtsev, V.A.; Lachartre, D.; Lafoux, H. E-mail: lafoux@cea.fr; Lamare, P.; Languillat, J.-C.; Laubier, L.; Laugier, J.-P.; Le Guen, Y.; Le Provost, H.; Le Van Suu, A.; Lemoine, L.; Lo Nigro, L.; Lo Presti, D.; Loucatos, S.; Louis, F.; Lyashuk, V.; Magnier, P.; Marcelin, M.; Margiotta, A.; Massol, A.; Masullo, R.; Mazeas, F.; Mazeau, B.; Mazure, A.; McMillan, J.E.; Michel, J.L.; Migneco, E.; Millot, C.; Mols, P.; Montanet, F.; Montaruli, T.; Morel, J.P.; Moscoso, L.; Musumeci, M.; Navas, S.; Nezri, E.; Nooren, G.J.; Oberski, J.; Olivetto, C.; Oppelt-Pohl, A.; Palanque-Delabrouille, N.; Papaleo, R.; Payre, P.; Perrin, P.; Petruccetti, M.; Petta, C.; Piattelli, P.; Poinsignon, J.; Potheau, R.; Queinec, Y.; Racca, C.; Raia, G.; Randazzo, N.; Rethore, F.; Riccobene, G.; Ricol, J.-S.; Ripani, M.; Roca-Blay, V.; Rolin, J.F.; Rostovstev, A.; Russo, G.V.; Sacquin, Y.; Salusti, E.; Schuller, J.-P.; Schuster, W.; Soirat, J.-P.; Souvorova, O.; Spooner, N.J.C.; Spurio, M.; Stolarczyk, T.; Stubert, D.; Taiuti, M.; Tao, C.; Tayalati, Y.; Thompson, L.F.

    2002-05-21

    The ANTARES collaboration is building a deep sea neutrino telescope in the Mediterranean Sea. This detector will cover a sensitive area of typically 0.1 km{sup 2} and will be equipped with about 1000 optical modules. Each of these optical modules consists of a large area photomultiplier and its associated electronics housed in a pressure resistant glass sphere. The design of the ANTARES optical module, which is a key element of the detector, has been finalized following extensive R and D studies and is reviewed here in detail.

  12. Microlensing modulation by binaries

    CERN Document Server

    Dubath, F; Durrer, R; Dubath, Florian; Gasparini, Maria Alice; Durrer, Ruth

    2006-01-01

    We compute the effect of the lens quadrupole on microlensing. The time dependence of the quadrupole can lead to specific modulations of the amplification signal. We study especially binary system lenses in our galaxy. The modulation is observable if the rotation period of the system is smaller than the time over which the amplification is significant and if the impact parameter of the passing light ray is sufficiently close to the Einstein radius so that the amplification is very large. Observations of this modulation can reveal important information on the quadrupole and thus on the gravitational radiation emitted by the lens.

  13. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... Prevention Recovery Substance Use and SUDs in LGBT Populations Treatment Trends & Statistics Women and Drugs Publications Search ... the link between drug abuse and HIV/AIDS, populations most at risk, trends in HIV/AIDS, and ...

  14. Medicare and Medicaid Linked Files

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Medicare-Medicaid Linked Enrollee Analytic Data Source (MMLEADS) has been developed to allow for the examination of all Medicare and Medicaid enrollment and...

  15. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... affect anyone. Watch the “d’cisions” Videos Campaign Materials After the Party Posters: We have developed posters ... the Learn the Link message. Campaign messages and materials were tested among various groups of young people, ...

  16. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... Drugs and HIV Learn the Link - Drugs and HIV Email Facebook Twitter 2005 –Ongoing Behaviors associated with ... Send the Message . Get the Facts What are HIV and AIDS? HIV (human immunodeficiency virus) is the ...

  17. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available Skip to main content En español Researchers Medical & Health Professionals Patients & Families Parents & Educators Children & Teens Search Connect with NIDA : Facebook LinkedIn Twitter YouTube Flickr RSS Menu ...

  18. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... other organizations in your tweets to spread the word even further. Tweet About Learn the Link To ... other organizations in your tweets to spread the word even further. Share with Flickr, Pinterest or Instagram ...

  19. Drugs + HIV, Learn the Link

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    Full Text Available ... Researchers Medical & Health Professionals Patients & Families Parents & Educators Children & Teens Search Connect with NIDA : Facebook LinkedIn Twitter ... Network TV Organizations: AIDS.gov AIDS Alliance for Children, Youth and Families The American Academy of Child & ...

  20. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... Drugs and HIV Learn the Link - Drugs and HIV Email Facebook Twitter 2005 –Ongoing Behaviors associated with ... Send the Message . Get the Facts What are HIV and AIDS? HIV (human immunodeficiency virus) is the ...

  1. Decouplink: Dynamic Links for Java

    DEFF Research Database (Denmark)

    Jensen, Martin Lykke Rytter; Jørgensen, Bo Nørregaard

    2011-01-01

    -based systems: On the one hand, violating the open/closed principle by allowing for modification compromises independent extensibility. On the other hand, trying to enforce the open/closed principle by prohibiting modification precludes unanticipated dimensions of extension. Dynamic links increase the number...... of dimensions of extension that can be exploited without performing modification of existing types. Thus, dynamic links make it possible to enforce the open/closed principle in situations where it would otherwise not be possible. We present Decouplink – a library-based implementation of dynamic links for Java.......We also present experience with the use of dynamic links during the evolution of a component-based control system....

  2. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... NIDA’s "Learn the Link" campaign continues to raise awareness among this generation of the real risks of ... Collaborators Thanks to Those Who Have Helped Raise Awareness of Our Campaign! NIDA acknowledges the following television ...

  3. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... Military Opioid Overdose Reversal with Naloxone (Narcan, Evzio) Pain Prevention Recovery Treatment Trends & Statistics Women and Drugs ... to your Web site. Please link these banners back to this site at: http://www.drugabuse.gov/ ...

  4. Advanced solderless flexible thermal link

    Science.gov (United States)

    Williams, Brian G.; Jensen, Scott M.; Batty, J. Clair

    1996-10-01

    Flexible thermal links play an important role int he thermal management of cryogenically cooled components. The purpose of these links is to provide a means of transferring heat from a cooled component to a cooler reservoir with little increase in temperature. The standard soldered approach although effective proves to be time consuming and contributes to added thermal impedances which degrade the performance of the link. For system with little tolerance for temperature differences between cooled components and a cooling source this is undesirable. The authors of this paper have developed a technique by which thin metal foil or braided wire can be attached to metal end blocks without any solder using the swaging process. Swaging provides a fast, simple method for providing a low thermal impedance between the foils and blocks. This paper describes the characteristics of these thermal links in terms of length, mass, thermal resistance, flexibility, and survivability.

  5. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... the message to young people and to parents, teachers, and the media about the link between ... status updates that you can easily copy and paste to help show your support for ...

  6. Linking Ethics and Economic Growth

    DEFF Research Database (Denmark)

    Foss, Nicolai Juul

    2012-01-01

    Hunt (2012) builds on his work concerning ethics and resource-advantage theory to link personal ethical standards, societal norms, and economic growth but offers few details concerning the precise mechanisms that link ethics and growth. This comment suggests a number of such mechanisms – for exam......Hunt (2012) builds on his work concerning ethics and resource-advantage theory to link personal ethical standards, societal norms, and economic growth but offers few details concerning the precise mechanisms that link ethics and growth. This comment suggests a number of such mechanisms...... – for example, the influence of prevailing ethical norms on the aggregate elasticity of substitution and, therefore, total factor productivity and growth....

  7. Study Links Disasters to Dementia

    Science.gov (United States)

    ... news/fullstory_161672.html Study Links Disasters to Dementia Losing home was tied to greater mental decline ... Earthquakes, floods and other natural disasters may raise dementia risk for seniors forced to leave their homes, ...

  8. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... affect anyone. Watch the “d’cisions” Videos Campaign Materials After the Party Posters: We have developed posters ... behaviors. NIDA researchers have studied and continue to study the links between drug abuse and HIV/AIDS. ...

  9. Drugs + HIV, Learn the Link

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    Full Text Available ... abuse and HIV infection. It contains information for young people, parents and teachers, and the media with links ... 177(1):355-361. How are Teens Affected? Young people are at risk for contracting HIV. In general, ...

  10. Protein Linked to Atopic Dermatitis

    Science.gov (United States)

    ... Research Matters NIH Research Matters January 14, 2013 Protein Linked to Atopic Dermatitis Normal skin from a ... in mice suggests that lack of a certain protein may trigger atopic dermatitis, the most common type ...

  11. Drugs + HIV, Learn the Link

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    Full Text Available ... patients who do not abuse drugs. In animal studies, methamphetamine has been shown to increase the amount ... behaviors. NIDA researchers have studied and continue to study the links between drug abuse and HIV/AIDS. ...

  12. Drugs + HIV, Learn the Link

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    Full Text Available ... Addiction Science Adolescent Brain Comorbidity College-Age & Young Adults Criminal Justice Drugged Driving Drug Testing Drugs and ... Link campaign. This campaign shows teens and young adults that non-injection drug use and alcohol use ...

  13. Drugs + HIV, Learn the Link

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    Full Text Available ... are at risk for contracting HIV. In general, middle and late teen years are when young people ... link between drug abuse and HIV. Post on Facebook or Twitter ; add photos to your Flickr , Pinterest , ...

  14. Drugs + HIV, Learn the Link

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    Full Text Available ... of HIV infection in the United States. Drugs can change the way the brain works, disrupting the ... linked and referred to as "HIV/AIDS." HIV can be transferred between people if an infected person's ...

  15. Drugs + HIV, Learn the Link

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    Full Text Available ... other organizations in your tweets to spread the word even further. Tweet About Learn the Link To ... other organizations in your tweets to spread the word even further. Share with Flickr, Pinterest or Instagram ...

  16. Drugs + HIV, Learn the Link

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    Full Text Available ... teens and young adults have never known a world without it. NIDA’s "Learn the Link" campaign continues ... NIDA TV PEERx Drugs & Health Blog The NIDA Science Fair Award for Addiction Science USA Science & Engineering ...

  17. Study Links Celiac Disease, Anorexia

    Science.gov (United States)

    ... medlineplus.gov/news/fullstory_164453.html Study Links Celiac Disease, Anorexia Chances of being diagnosed with eating ... April 4, 2017 (HealthDay News) -- Young women with celiac disease may face a heightened risk of being ...

  18. Drugs + HIV, Learn the Link

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    Full Text Available ... causes AIDS (acquired immune deficiency syndrome). AIDS is a disease of the immune system for which there ... causes (AIDS) are often linked and referred to as "HIV/AIDS." HIV can be transferred between people ...

  19. Drugs + HIV, Learn the Link

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    Full Text Available ... increasingly at risk for HIV infection through risky sexual behaviors. NIDA researchers have studied and continue to study the links between drug abuse and HIV/AIDS. In the early years of ...

  20. Intermediate links of line arrangements

    CERN Document Server

    Bodin, Arnaud

    2012-01-01

    We investigate several topological properties of line arrangements. The first result is that two generic complex line arrangements are equivalent. In fact for a line arrangement A we associate its defining polynomial f= prod_i (a_ix+b_iy+c_i), so that A = (f=0). We even prove that the defining polynomials of two generic line arrangements are topologically equivalent. In higher dimension the related result is that within a family of equivalent hyperplane arrangements the defining polynomials are topologically equivalent. A second type of objects associated to a line arrangement are links A cap S^3_r(0) obtained by intersecting the arrangement with some spheres. Several topics are discussed: (a) some link configurations can be realized by complex line arrangements but not by real line arrangements; (b) if we intersect the arrangements with a vertical band instead of a sphere, what link configurations can be obtained? (c) relations between link configurations obtained by bands and spheres.

  1. Module bay with directed flow

    Science.gov (United States)

    Torczynski, John R.

    2001-02-27

    A module bay requires less cleanroom airflow. A shaped gas inlet passage can allow cleanroom air into the module bay with flow velocity preferentially directed toward contaminant rich portions of a processing module in the module bay. Preferential gas flow direction can more efficiently purge contaminants from appropriate portions of the module bay, allowing a reduced cleanroom air flow rate for contaminant removal. A shelf extending from an air inlet slit in one wall of a module bay can direct air flowing therethrough toward contaminant-rich portions of the module bay, such as a junction between a lid and base of a processing module.

  2. HIGHER FREQUENCY ULTRASONIC LIGHT MODULATORS.

    Science.gov (United States)

    LIGHT), (* MODULATORS , (*ULTRASONIC RADIATION, MODULATORS ), OPTICAL COMMUNICATIONS, BANDWIDTH, TRANSDUCERS, HIGH FREQUENCY, VERY HIGH FREQUENCY, ATTENUATION, DATA PROCESSING, OPTICAL EQUIPMENT, ANALOG COMPUTERS, THEORY.

  3. Linking DC together with TRSL

    DEFF Research Database (Denmark)

    Haxthausen, Anne Elisabeth; Yong, X.

    2000-01-01

    Duration Calculus (DC) is an interval-based real-time logic, which can be used in capturing and eliciting users' real-time requirements. The Timed RAISE Specification Language (TRSL) is an extension of the RAISE Specification Language with real-time features. This paper links DC and TRSL together...... approach for linking state-based real-time logics together with event-based, timed process algebra languages....

  4. Linked data and user interaction

    CERN Document Server

    Cervone, H Frank

    2015-01-01

    This collection of research papers provides extensive information on deploying services, concepts, and approaches for using open linked data from libraries and other cultural heritage institutions. With a special emphasis on how libraries and other cultural heritage institutions can create effective end user interfaces using open, linked data or other datasets. These papers are essential reading for any one interesting in user interface design or the semantic web.

  5. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... Link . Be sure to check out the NIDA Facebook page and tag us in your posts! Learn the link between drug abuse and HIV. http://1.usa.gov/1z20ww6 How many of us think about HIV/AIDS when we’re at parties or hanging out with friends? It’s a topic you can’t ignore. Learn ...

  6. Linking Ethics and Economic Growth

    DEFF Research Database (Denmark)

    Foss, Nicolai Juul

    2012-01-01

    Hunt (2012) builds on his work concerning ethics and resource-advantage theory to link personal ethical standards, societal norms, and economic growth but offers few details concerning the precise mechanisms that link ethics and growth. This comment suggests a number of such mechanisms...... – for example, the influence of prevailing ethical norms on the aggregate elasticity of substitution and, therefore, total factor productivity and growth....

  7. 45 Km Horizontal Path Optical Link Experiment

    Science.gov (United States)

    Biswas, A.; Ceniceros, J.; Novak, M.; Jeganathan, M.; Portillo, A.; Erickson, D.; Depew, J.; Sanii, B.; Lesh, J. R.

    2000-01-01

    Mountain-top to mountain-top optical link experiments have been initiated at JPL, in order to perform a systems level evaluation of optical communications. Progress made so far is reported. ne NASA, JPL developed optical communications demonstrator (OCD) is used to transmit a laser signal from Strawberry Peak (SP), located in the San Bernadino mountains of California. This laser beam is received by a 0.6 m aperture telescope at JPL's Table Mountain Facility (TMF), located in Wrightwood, California. The optical link is bi-directional with the TMF telescope transmitting a continuous 4-wave (cw) 780 run beacon and the OCD sending back a 840 nm, 100 - 500 Mbps pseudo noise (PN) modulated, laser beam. The optical link path is at an average altitude of 2 km above sea level, covers a range of 46.8 km and provides an atmospheric channel equivalent to approx. 4 air masses. Average received power measured at either end fall well within the uncertainties predicted by link analysis. The reduction in normalized intensity variance (sigma(sup 2, sub I)) for the 4-beam beacon, compared to each individual beam, at SP, was from approx. 0.68 to 0.22. With some allowance for intra-beam mis-alignment, this is consistent with incoherent averaging. The sigma(sup2, sub I) measured at TMF approx. 0.43 +/- 0.22 exceeded the expected aperture averaged value of less than 0.1, probably because of beam wander. The focused spot sizes of approx. 162 +/- 6 microns at the TMF Coude and approx. 64 +/- 3 microns on the OCD compare to the predicted size range of 52 - 172 microns and 57 - 93 microns, respectively. This is consistent with 4 - 5 arcsec of atmospheric "seeing". The preliminary evaluation of OCD's fine tracking indicates that the uncompensated tracking error is approx. 3.3 micro rad compared to approx. 1.7 micro rad observed in the laboratory. Fine tracking performance was intermittent, primarily due to beacon fades on the OCD tracking sensor. The best bit error rates observed while

  8. A photovoltaic module

    DEFF Research Database (Denmark)

    2013-01-01

    The present invention relates to a photovoltaic module comprising a carrier substrate, said carrier substrate carrying a purely printed structure comprising printed positive and negative module terminals, a plurality of printed photovoltaic cell units each comprising one or more printed...... photovoltaic cells, wherein the plurality of printed photovoltaic cell units are electrically connected in series between the positive and the negative module terminals such that any two neighbouring photovoltaic cell units are electrically connected by a printed interconnecting electrical conductor....... The carrier substrate comprises a foil and the total thickness of the photovoltaic module is below 500 [mu]m. Moreover, the nominal voltage level between the positive and the negative terminals is at least 5 kV DC....

  9. Ultrasound Modulated Bioluminescence Tomography

    CERN Document Server

    Bal, Guillaume

    2013-01-01

    We propose a method to reconstruct the density of a luminescent source in a highly-scattering medium from ultrasound modulated optical measurements. Our approach is based on the solution to a hybrid inverse source problem for the diffusion equation.

  10. Isothermal Containment Module

    Science.gov (United States)

    1999-01-01

    Isothermal Containment Modules are the temperature-controlling carrier that BioServe built to carry Commercial Generic Bioprocessing Apparatus (CGBA) and in the future, Space Automated Bioproduct Lab (SABL) to the International Space Station.

  11. GREET Pretreatment Module

    Energy Technology Data Exchange (ETDEWEB)

    Adom, Felix K.; Dunn, Jennifer B.; Han, Jeongwoo

    2014-09-01

    A wide range of biofuels and biochemicals can be produced from biomass via different pretreatment technologies that yield sugars. This report documents the material and energy flows that occur when fermentable sugars from four lignocellulosic feedstocks (corn stover, miscanthus, switchgrass, and poplar) are produced via dilute acid pretreatment and ammonia fiber expansion. These flows are documented for inclusion in the pretreatment module of the Greenhouses Gases, Regulated Emissions, and Energy Use in Transportation (GREET) model. Process simulations of each pretreatment technology were developed in Aspen Plus. Material and energy consumption data from Aspen Plus were then compiled in the GREET pretreatment module. The module estimates the cradle-to-gate fossil energy consumption (FEC) and greenhouse gas (GHG) emissions associated with producing fermentable sugars. This report documents the data and methodology used to develop this module and the cradle-to-gate FEC and GHG emissions that result from producing fermentable sugars.

  12. Top Local Cohomology Modules

    Institute of Scientific and Technical Information of China (English)

    Mohammad T. Dibaei; Siamak Yassemi

    2007-01-01

    For a finitely generated module M over a commutative Noetherian local ring (R, m), it is shown that there exist only a finite number of non-isomorphic top localeohomology modules Hdim(M) (M) for all ideals a of RIt is also shown that for a giveninteger r ≥ 0, if Hra(R/p) is zero for all p in Supp(M), then Hia(M)=0 for all I ≥ r.

  13. Groups, rings, modules

    CERN Document Server

    Auslander, Maurice

    2014-01-01

    This classic monograph is geared toward advanced undergraduates and graduate students. The treatment presupposes some familiarity with sets, groups, rings, and vector spaces. The four-part approach begins with examinations of sets and maps, monoids and groups, categories, and rings. The second part explores unique factorization domains, general module theory, semisimple rings and modules, and Artinian rings. Part three's topics include localization and tensor products, principal ideal domains, and applications of fundamental theorem. The fourth and final part covers algebraic field extensions

  14. Absolutely Indecomposable Modules

    CERN Document Server

    Göbel, Rüdiger

    2007-01-01

    A module is called absolutely indecomposable if it is directly indecomposable in every generic extension of the universe. We want to show the existence of large abelian groups that are absolutely indecomposable. This will follow from a more general result about R-modules over a large class of commutative rings R with endomorphism ring R which remains the same when passing to a generic extension of the universe. It turns out that `large' in this context has the precise meaning, namely being smaller then the first omega-Erdos cardinal defined below. We will first apply result on large rigid trees with a similar property established by Shelah in 1982, and will prove the existence of related ` R_omega-modules' (R-modules with countably many distinguished submodules) and finally pass to R-modules. The passage through R_omega-modules has the great advantage that the proofs become very transparent essentially using a few `linear algebra' arguments accessible also for graduate students. The result gives a new constru...

  15. Photovoltaic module reliability workshop

    Energy Technology Data Exchange (ETDEWEB)

    Mrig, L. (ed.)

    1990-01-01

    The paper and presentations compiled in this volume form the Proceedings of the fourth in a series of Workshops sponsored by Solar Energy Research Institute (SERI/DOE) under the general theme of photovoltaic module reliability during the period 1986--1990. The reliability Photo Voltaic (PV) modules/systems is exceedingly important along with the initial cost and efficiency of modules if the PV technology has to make a major impact in the power generation market, and for it to compete with the conventional electricity producing technologies. The reliability of photovoltaic modules has progressed significantly in the last few years as evidenced by warranties available on commercial modules of as long as 12 years. However, there is still need for substantial research and testing required to improve module field reliability to levels of 30 years or more. Several small groups of researchers are involved in this research, development, and monitoring activity around the world. In the US, PV manufacturers, DOE laboratories, electric utilities and others are engaged in the photovoltaic reliability research and testing. This group of researchers and others interested in this field were brought together under SERI/DOE sponsorship to exchange the technical knowledge and field experience as related to current information in this important field. The papers presented here reflect this effort.

  16. Mathematical Model of Bridge-Linked Photovoltaic Arrays Operating Under Irregular Conditions

    OpenAIRE

    Juan D. Bastidas-Rodríguez; Carlos A. Ramos-Paja; Luz A. Trejos-Grisales

    2013-01-01

    This paper presents a mathematical procedure to model a photovoltaic array (N rows and M columns) in bridge-linked configuration operating under regular and irregular conditions. The proposed procedure uses the ideal single-diode model representation for each photovoltaic module and the Shockley equation to represent each bypass diode. To pose the system of NxM non-linear equations required to obtain the voltages of each module of the array, the proposed model apply the Kirchhoff current law ...

  17. Yetter-Drinfel‘d Module and Convolution Module

    Institute of Scientific and Technical Information of China (English)

    张良云; 王栓宏

    2002-01-01

    In this paper,we first give a sufficent and necessary condition for a Hopf algebra to be a Yetter-Drinfel'd module,and prove that the finite dual of a Yetter-Drinfel'd module is still a Yetter-Drinfel'd module,Finally,we introduce a concept of convolution module.

  18. Superstability for Generalized Module Left Derivations and Generalized Module Derivations on a Banach Module (I

    Directory of Open Access Journals (Sweden)

    Rassias JM

    2009-01-01

    Full Text Available We discuss the superstability of generalized module left derivations and generalized module derivations on a Banach module. Let be a Banach algebra and a Banach -module, and . The mappings , and are defined and it is proved that if (resp., is dominated by then is a generalized (resp., linear module- left derivation and is a (resp., linear module- left derivation. It is also shown that if (resp., is dominated by then is a generalized (resp., linear module- derivation and is a (resp., linear module- derivation.

  19. ASTP crewmen in Docking Module trainer during training session at JSC

    Science.gov (United States)

    1975-01-01

    An interior view of the Docking Module trainer in bldg 35 during Apollo Soyuz Test Project (ASTP) joint crew training at JSC. Astronaut Donald K. Slayton (right) is the docking module pilot of the American ASTP prime crew. The other man is Cosmonaut Valeriy N. Kubasov, engineer on the Soviet ASTP first (prime) crew. The training session simulated activities on the second day in space. The Docking module is designed to link the Apollo and Soyuz spacecraft.

  20. Free-space optical communication link using perfect vortex beams carrying orbital angular momentum (OAM)

    Science.gov (United States)

    Zhu, Fuquan; Huang, Sujuan; Shao, Wei; Zhang, Jie; Chen, Musheng; Zhang, Weibing; Zeng, Junzhang

    2017-08-01

    We experimentally demonstrate a free-space optical communication link using perfect vortex beams. Perfect vortex beams with different topological charges are generated using a phase-modulation-type spatial light modulator (SLM) loaded with novel phase holograms based on the Bessel function. With the help of a microscope objective and simple lens, perfect vortex beams are transmitted effectively for a certain distance. After completing the demodulation of perfect vortex beams carrying OFDM 16-QAM signals and a series of offline processing on the Gaussian bright spot demodulated from the perfect vortex beams, we also achieve a communication link. The constellations and mean bit error rates (BER) of subcarriers are shown.

  1. Joint Adaptive Modulation and Combining for Hybrid FSO/RF Systems

    KAUST Repository

    Rakia, Tamer

    2015-11-12

    In this paper, we present and analyze a new transmission scheme for hybrid FSO/RF communication system based on joint adaptive modulation and adaptive combining. Specifically, the data rate on the FSO link is adjusted in discrete manner according to the FSO link\\'s instantaneous received signal-to-noise-ratio (SNR). If the FSO link\\'s quality is too poor to maintain the target bit-error-rate, the system activates the RF link along with the FSO link. When the RF link is activated, simultaneous transmission of the same modulated data takes place on both links, where the received signals from both links are combined using maximal ratio combining scheme. In this case, the data rate of the system is adjusted according to the instantaneous combined SNRs. Novel analytical expression for the cumulative distribution function (CDF) of the received SNR for the proposed adaptive hybrid system is obtained. This CDF expression is used to study the spectral and outage performances of the proposed adaptive hybrid FSO/RF system. Numerical examples are presented to compare the performance of the proposed adaptive hybrid FSO/RF system with that of switch-over hybrid FSO/RF and FSO-only systems employing the same adaptive modulation schemes. © 2015 IEEE.

  2. LinkMind: link optimization in swarming mobile sensor networks.

    Science.gov (United States)

    Ngo, Trung Dung

    2011-01-01

    A swarming mobile sensor network is comprised of a swarm of wirelessly connected mobile robots equipped with various sensors. Such a network can be applied in an uncertain environment for services such as cooperative navigation and exploration, object identification and information gathering. One of the most advantageous properties of the swarming wireless sensor network is that mobile nodes can work cooperatively to organize an ad-hoc network and optimize the network link capacity to maximize the transmission of gathered data from a source to a target. This paper describes a new method of link optimization of swarming mobile sensor networks. The new method is based on combination of the artificial potential force guaranteeing connectivities of the mobile sensor nodes and the max-flow min-cut theorem of graph theory ensuring optimization of the network link capacity. The developed algorithm is demonstrated and evaluated in simulation.

  3. LinkMind: Link Optimization in Swarming Mobile Sensor Networks

    Directory of Open Access Journals (Sweden)

    Trung Dung Ngo

    2011-08-01

    Full Text Available A swarming mobile sensor network is comprised of a swarm of wirelessly connected mobile robots equipped with various sensors. Such a network can be applied in an uncertain environment for services such as cooperative navigation and exploration, object identification and information gathering. One of the most advantageous properties of the swarming wireless sensor network is that mobile nodes can work cooperatively to organize an ad-hoc network and optimize the network link capacity to maximize the transmission of gathered data from a source to a target. This paper describes a new method of link optimization of swarming mobile sensor networks. The new method is based on combination of the artificial potential force guaranteeing connectivities of the mobile sensor nodes and the max-flow min-cut theorem of graph theory ensuring optimization of the network link capacity. The developed algorithm is demonstrated and evaluated in simulation.

  4. X chromosome inactivation and X-linked mental retardation

    Energy Technology Data Exchange (ETDEWEB)

    Willard, H.F. [Case Western Reserve Univ. School of Medicine, Cleveland, OH (United States)]|[Univ. Hospitals of Cleveland, OH (United States)

    1996-07-12

    The expression of X-linked genes in females heterozygous for X-linked defects can be modulated by epigenetic control mechanisms that constitute the X chromosome inactivation pathway. At least four different effects have been found to influence, in females, the phenotypic expression of genes responsible for X-linked mental retardation (XLMR). First, non-random X inactivation, due either to stochastic or genetic factors, can result in tissues in which one cell type (for example, that in which the X chromosome carrying a mutant XLMR gene is active) dominates, instead of the normal mosaic cell population expected as a result of random X inactivation. Second, skewed inactivation of the normal X in individuals carrying a deletion of part of the X chromosome has been documented in a number of mentally retarded females. Third, functional disomy of X-linked genes that are expressed inappropriately due to the absence of X inactivation has been found in mentally retarded females with structurally abnormal X chromosomes that do not contain the X inactivation center. And fourth, dose-dependent overexpression of X-linked genes that normally {open_quotes}escape{close_quotes} X inactivation may account for the mental and developmental delay associated with increasing numbers of otherwise inactive X chromosomes in individuals with X chromosome aneuploidy. 53 refs., 1 fig.

  5. Standard Modules, Induction and the Temperley-Lieb Algebra

    CERN Document Server

    Ridout, David

    2012-01-01

    The basic properties of the Temperley-Lieb algebra TL_n with parameter beta = q + q^{-1}, for q any non-zero complex number, are reviewed in a pedagogical way. The link and standard (cell) modules that appear in numerous physical applications are defined and a natural bilinear form on the standard modules is used to characterize their maximal submodules. When this bilinear form has a non-trivial radical, some of the standard modules are reducible and TL_n is non-semisimple. This happens only when q is a root of unity. Use of restriction and induction allows for a finer description of the structure of the standard modules. Finally, a particular central element F_n of TL_n is studied; its action is shown to be non-diagonalisable on certain indecomposable modules and this leads to a proof that the radicals of the standard modules are irreducible. Moreover, the space of homomorphisms between standard modules is completely determined. The principal indecomposable modules are then computed concretely in terms of st...

  6. Universal enveloping crossed module of Leibniz crossed modules and representations

    Science.gov (United States)

    Casado, Rafael F.; García-Martínez, Xabier; Ladra, Manuel

    2016-03-01

    The universal enveloping algebra functor UL: Lb → Alg, defined by Loday and Pirashvili [1], is extended to crossed modules. Then we construct an isomorphism between the category of representations of a Leibniz crossed module and the category of left modules over its universal enveloping crossed module of algebras. Note that the procedure followed in the proof for the Lie case cannot be adapted, since the actor in the category of Leibniz crossed modules does not always exist.

  7. Acquisition and Pointing for Mars Optical Access Link

    Science.gov (United States)

    Regehr, Martin; Kovalik, Joseph; Biswas, Abhijit

    2009-01-01

    Optical characteristics can potentially benefit "access" links at Mars when transmitting data from surface to orbiting assets because of the higher gain and modulation bandwidth, compared to radio frequency (RF). Furthermore, higher bits/kg/W can be realized with low mass and power optical systems, enabling the streaming of high definition imagery. In this paper we present a conceptual design for a low complexity, autonomous optical communications link for returning data at 50-200 Mb/s from the Martian surface and for lower forward data rates of 50 kb/s to the surface. The pointing control is simplified by widening the transmitted laser beams (0.5 - 2.0 mrad) for the short distance (400-1200 Km) links. Link acquisition is based on the orbiter transceiver (OT) "blind"-pointing a laser beam to illuminate the lander transceiver (LT) on the surface. The LT acquires the link with a spectrally-filtered wide-field-of-view camera and subsequently tracks the orbiter transceiver with a two-axis, stepper-motor-actuator, to send back a laser modulated with high-rate data to the orbiting asset. The system design also has a provision for the OT transitioning from blind-pointing to closed loop tracking once it acquires the signal from the lander transceiver. Results from successful ground-based demonstrations performed at JPL, in which the pointing rate required to track an orbiter was emulated by mounting both transceivers on rotating stages, and in which we transmitted live video and pseudo-random data streams, are presented.

  8. Microeconomics of 300-mm process module control

    Science.gov (United States)

    Monahan, Kevin M.; Chatterjee, Arun K.; Falessi, Georges; Levy, Ady; Stoller, Meryl D.

    2001-08-01

    Simple microeconomic models that directly link metrology, yield, and profitability are rare or non-existent. In this work, we validate and apply such a model. Using a small number of input parameters, we explain current yield management practices in 200 mm factories. The model is then used to extrapolate requirements for 300 mm factories, including the impact of simultaneous technology transitions to 130nm lithography and integrated metrology. To support our conclusions, we use examples relevant to factory-wide photo module control.

  9. Seismic link at plate boundary

    Indian Academy of Sciences (India)

    Faical Ramdani; Omar Kettani; Benaissa Tadili

    2015-06-01

    Seismic triggering at plate boundaries has a very complex nature that includes seismic events at varying distances. The spatial orientation of triggering cannot be reduced to sequences from the main shocks. Seismic waves propagate at all times in all directions, particularly in highly active zones. No direct evidence can be obtained regarding which earthquakes trigger the shocks. The first approach is to determine the potential linked zones where triggering may occur. The second step is to determine the causality between the events and their triggered shocks. The spatial orientation of the links between events is established from pre-ordered networks and the adapted dependence of the spatio-temporal occurrence of earthquakes. Based on a coefficient of synchronous seismic activity to grid couples, we derive a network link by each threshold. The links of high thresholds are tested using the coherence of time series to determine the causality and related orientation. The resulting link orientations at the plate boundary conditions indicate that causal triggering seems to be localized along a major fault, as a stress transfer between two major faults, and parallel to the geothermal area extension.

  10. Characterizations of Graded Distributive Modules

    Institute of Scientific and Technical Information of China (English)

    Qinghua Chen; Chang'an Li

    2002-01-01

    In this paper, we give some characterizations of graded distributive modules, prove some interesting results between graded rings (modules) and lattices under finiteness conditions, and investigate the direct sum of graded distributive modules in terms of orders of graded submodules and homomorphisms of graded factor modules.

  11. APP Function and Lipids: A Bidirectional Link.

    Science.gov (United States)

    Grimm, Marcus O W; Mett, Janine; Grimm, Heike S; Hartmann, Tobias

    2017-01-01

    Extracellular neuritic plaques, composed of aggregated amyloid-β (Aβ) peptides, are one of the major histopathological hallmarks of Alzheimer's disease (AD), a progressive, irreversible neurodegenerative disorder and the most common cause of dementia in the elderly. One of the most prominent risk factor for sporadic AD, carrying one or two aberrant copies of the apolipoprotein E (ApoE) ε4 alleles, closely links AD to lipids. Further, several lipid classes and fatty acids have been reported to be changed in the brain of AD-affected individuals. Interestingly, the observed lipid changes in the brain seem not only to be a consequence of the disease but also modulate Aβ generation. In line with these observations, protective lipids being able to decrease Aβ generation and also potential negative lipids in respect to AD were identified. Mechanistically, Aβ peptides are generated by sequential proteolytic processing of the amyloid precursor protein (APP) by β- and γ-secretase. The α-secretase appears to compete with β-secretase for the initial cleavage of APP, preventing Aβ production. All APP-cleaving secretases as well as APP are transmembrane proteins, further illustrating the impact of lipids on Aβ generation. Beside the pathological impact of Aβ, accumulating evidence suggests that Aβ and the APP intracellular domain (AICD) play an important role in regulating lipid homeostasis, either by direct effects or by affecting gene expression or protein stability of enzymes involved in the de novo synthesis of different lipid classes. This review summarizes the current literature addressing the complex bidirectional link between lipids and AD and APP processing including lipid alterations found in AD post mortem brains, lipids that alter APP processing and the physiological functions of Aβ and AICD in the regulation of several lipid metabolism pathways.

  12. High-speed digital fiber optic links for satellite traffic

    Science.gov (United States)

    Daryoush, A. S.; Ackerman, E.; Saedi, R.; Kunath, R. R.; Shalkhauser, K.

    1989-09-01

    Large aperture phased array antennas operating at millimeter wave frequencies are designed for space-based communications and imaging platforms. Array elements are comprised of active T/R modules which are linked to the central processing unit through high-speed fiber-optic networks. The system architecture satisfying system requirements at millimeter wave frequency is T/R level data mixing where data and frequency reference signals are distributed independently before mixing at the T/R modules. This paper demonstrates design procedures of a low loss high-speed fiber-optic link used for transmission of data signals over 600-900 MHz bandwidth inside satellite. The fiber-optic link is characterized for transmission of analog and digital data. A dynamic range of 79 dB/MHz was measured for analog data over the bandwidth. On the other hand, for bursted SMSK satellite traffic at 220 Mbps rates, BER of 2 x 10 to the -7th was measured for E(b)/N(o) of 14.3 dB.

  13. The Optical Links of the ATLAS SemiConductor Tracker

    CERN Document Server

    Abdesselam, A; Apsimon, R; Band, C; Barr, C; Batchelor, L; Bates, R; Bell, P; Bernabeu, J; Bizzell, J; Brenner, R; Brodbeck, T; Bruckman De Renstrom, P; Buttar, C; Carter, J; Charlton, D; Cheplakov, A; Chilingarov, A; Chu, M-L; Colijn, A-P; Dawson, I; Demirkõz, B; de Jong, P; Dervan, P; Dolezal, Z; Dowell, J; Escobar, P; Spencer, E; Ekelöf, T J C; Eklund, L; Ferrere, D; Fraser, T; French, M; French, R; Fuster, J; Gallop, B; García, C; Goodrick, M; Greenall, A; Grillo, A; Grosse-Knetter, J; Hartjes, F; Hessey, N; Hill, J C; Homer, J; Hou, L; Hughes, G; Ikegami, Y; Issever, C; Jackson, J; Jones, M; Jones, T J; Jovanovic, P; Koffeman, E; Kodys, P; Kohriki, T; Lee, S-C; Lester, C; Limper, M; Lindsay, S W; Lozano, M; Macwaters, C; Magrath, C; Mahout, G; Mandic, I; Matheson, J; McMahon, T; Mikulec, B; Muijs, A; Morrissey, M; Nichols, A; Nickerson, R; O'Shea, V; Pagenis, S; Parker, M; Pater, J; Perrin, E; Pernegger, H; Peeters, S; Phillips, P; Postranecky, M; Robinson, D; Robson, A; Rudge, A; Sandaker, H; Sedlak, K; Smith, N A; Stapnes, S; Stugu, B; Teng, P K; Terada, S; Tricoli, A; Tyndel, M; Ujiie, N; Ullán, M; Unno, Y; van der Kraaij, E; Van Vulpen, I; Viehhauser, G; Vossebeld, J H; Warren, M; Wastie, R; Weidberg, A; Wells, P; White, D; Wilson, J

    2007-01-01

    Optical links are used for the readout of the 4088 silicon microstrip modules that make up the SemiConductor Tracker of the ATLAS experiment at the CERN Large Hadron Collider (LHC). The optical link requirements are reviewed, with particular emphasis on the very demanding environment at the LHC. The on-detector components have to operate in high radiation levels for 10 years, with no maintenance, and there are very strict requirements on power consumption, material and space. A novel concept for the packaging of the on-detector optoelectronics has been developed to meet these requirements. The system architecture, including its redundancy features, is explained and the critical on-detector components are described. The results of the extensive Quality Assurance performed during all steps of the assembly are discussed. Optical links are used for the readout of the 4088 silicon microstrip modules that make up the SemiConductor Tracker of the ATLAS experiment at the CERN Large Hadron Collider (LHC). The optical ...

  14. Links

    OpenAIRE

    Alessandra Russo

    2006-01-01

    La lista de enlaces ofrecida a continuación tiene como objetivo la creación de una base de datos sobre los principales sitios de interés para el estudio de la imagen (en America Latina y más allá). Se ha tratado de incluir una vasta gama de instituciones (museos, colecciones, institutos), representando sin embargo también a revistas, proyectos de investigación, y catálogos en línea. Sin tener la pretensión de ser exhaustiva, esta selección es evolutiva y se pone al día continuamente. MuseosI...

  15. Links

    Directory of Open Access Journals (Sweden)

    Alessandra Russo

    2006-02-01

    Full Text Available La lista de enlaces ofrecida a continuación tiene como objetivo la creación de una base de datos sobre los principales sitios de interés para el estudio de la imagen (en America Latina y más allá. Se ha tratado de incluir una vasta gama de instituciones (museos, colecciones, institutos, representando sin embargo también a revistas, proyectos de investigación, y catálogos en línea. Sin tener la pretensión de ser exhaustiva, esta selección es evolutiva y se pone al día continuamente. MuseosI...

  16. Integrated unaligned resonant modulator tuning

    Energy Technology Data Exchange (ETDEWEB)

    Zortman, William A.; Lentine, Anthony L.

    2017-10-03

    Methods and systems for tuning a resonant modulator are disclosed. One method includes receiving a carrier signal modulated by the resonant modulator with a stream of data having an approximately equal number of high and low bits, determining an average power of the modulated carrier signal, comparing the average power to a predetermined threshold, and operating a tuning device coupled to the resonant modulator based on the comparison of the average power and the predetermined threshold. One system includes an input structure, a plurality of processing elements, and a digital control element. The input structure is configured to receive, from the resonant modulator, a modulated carrier signal. The plurality of processing elements are configured to determine an average power of the modulated carrier signal. The digital control element is configured to operate a tuning device coupled to the resonant modulator based on the average power of the modulated carrier signal.

  17. Deformation of Linked Polymer Coils

    Institute of Scientific and Technical Information of China (English)

    董朝霞; 李明远; 吴肇亮; 林梅钦

    2003-01-01

    Linked polymer solution (LPS) is defined as the solution of linked polymer coils (LPCs) dispersed in water, composed of low concentration partially hydrolyzed polyacrylamide (HPAM) and aluminum citrate (crosslinker). In the work, the conformational changes of LPCs under different conditions were investigated by the methods of membrane filtering under low pressure, dynamic light scattering and core flooding experiments. The results showed that in some conditions the LPCs could be compressed mechanically to 1/158.5 of their original volume because of relatively lower HPAM cross-linking. The hydration property of LPCs was similar to that of normal polymer coils. The deformation of LPCs was more restricted than that of ordinary polymer coils under the flow shear stress or the shift of hydration equilibrium caused in the variation of the electrolyte concentration which is responsible for the effective plugging in the throats of porous media when LPCs are used for deep diverting.

  18. Link Prediction via Matrix Completion

    CERN Document Server

    Pech, Ratha; Pan, Liming; Cheng, Hong; Zhou, Tao

    2016-01-01

    Inspired by practical importance of social networks, economic networks, biological networks and so on, studies on large and complex networks have attracted a surge of attentions in the recent years. Link prediction is a fundamental issue to understand the mechanisms by which new links are added to the networks. We introduce the method of robust principal component analysis (robust PCA) into link prediction, and estimate the missing entries of the adjacency matrix. On one hand, our algorithm is based on the sparsity and low rank property of the matrix, on the other hand, it also performs very well when the network is dense. This is because a relatively dense real network is also sparse in comparison to the complete graph. According to extensive experiments on real networks from disparate fields, when the target network is connected and sufficiently dense, whatever it is weighted or unweighted, our method is demonstrated to be very effective and with prediction accuracy being considerably improved comparing wit...

  19. The OceanLink Project

    Science.gov (United States)

    Narock, T.; Arko, R. A.; Carbotte, S. M.; Chandler, C. L.; Cheatham, M.; Finin, T.; Hitzler, P.; Krisnadhi, A.; Raymond, L. M.; Shepherd, A.; Wiebe, P. H.

    2014-12-01

    A wide spectrum of maturing methods and tools, collectively characterized as the Semantic Web, is helping to vastly improve the dissemination of scientific research. Creating semantic integration requires input from both domain and cyberinfrastructure scientists. OceanLink, an NSF EarthCube Building Block, is demonstrating semantic technologies through the integration of geoscience data repositories, library holdings, conference abstracts, and funded research awards. Meeting project objectives involves applying semantic technologies to support data representation, discovery, sharing and integration. Our semantic cyberinfrastructure components include ontology design patterns, Linked Data collections, semantic provenance, and associated services to enhance data and knowledge discovery, interoperation, and integration. We discuss how these components are integrated, the continued automated and semi-automated creation of semantic metadata, and techniques we have developed to integrate ontologies, link resources, and preserve provenance and attribution.

  20. Spatial Terahertz Modulator

    Science.gov (United States)

    Xie, Zhenwei; Wang, Xinke; Ye, Jiasheng; Feng, Shengfei; Sun, Wenfeng; Akalin, Tahsin; Zhang, Yan

    2013-11-01

    Terahertz (THz) technology is a developing and promising candidate for biological imaging, security inspection and communications, due to the low photon energy, the high transparency and the broad band properties of the THz radiation. However, a major encountered bottleneck is lack of efficient devices to manipulate the THz wave, especially to modulate the THz wave front. A wave front modulator should allow the optical or electrical control of the spatial transmission (or reflection) of an input THz wave and hence the ability to encode the information in a wave front. Here we propose a spatial THz modulator (STM) to dynamically control the THz wave front with photo-generated carriers. A computer generated THz hologram is projected onto a silicon wafer by a conventional spatial light modulator (SLM). The corresponding photo-generated carrier spatial distribution will be induced, which forms an amplitude hologram to modulate the wave front of the input THz beam. Some special intensity patterns and vortex beams are generated by using this method. This all-optical controllable STM is structure free, high resolution and broadband. It is expected to be widely used in future THz imaging and communication systems.

  1. Superconducting optical modulator

    Science.gov (United States)

    Bunt, Patricia S.; Ference, Thomas G.; Puzey, Kenneth A.; Tanner, David B.; Tache, Nacira; Varhue, Walter J.

    2000-12-01

    An optical modulator based on the physical properties of high temperature superconductors has been fabricated and tested. The modulator was constructed form a film of Yttrium Barium Copper Oxide (YBCO) grown on undoped silicon with a buffer layer of Yttria Stabilized Zirconia. Standard lithographic procedures were used to pattern the superconducting film into a micro bridge. Optical modulation was achieved by passing IR light through the composite structure normal to the micro bridge and switching the superconducting film in the bridge region between the superconducting and non-superconducting states. In the superconducting state, IR light reflects from the superconducting film surface. When a critical current is passed through the micro bridge, it causes the film in this region to switch to the non-superconducting state allowing IR light to pass through it. Superconducting materials have the potential to switch between these two states at speeds up to 1 picosecond using electrical current. Presently, fiber optic transmission capacity is limited by the rate at which optical data can be modulated. The superconducting modulator, when combined with other components, may have the potential to increase the transmission capacity of fiber optic lines.

  2. When He Said Linking, He Really Meant Linking

    Science.gov (United States)

    Chudnov, Daniel

    2009-01-01

    There are many reasons to improve web links, starting with their design. The author tends to think about "design" on the web in terms of two things: (1) graphic/industrial design; and (2) human usability. A nice, clean URI (uniform resource identifier) that does not change, is readable to humans, is amenable to common web behaviors such as…

  3. LinkMind: Link Optimization in Swarming Mobile Sensor Networks

    DEFF Research Database (Denmark)

    Ngo, Trung Dung

    2012-01-01

    optimization of swarming mobile sensor networks. The new method is based on combination of the artificial potential force guaranteeing connectivities of the mobile sensor nodes and the max-flow min-cut theorem of graph theory ensuring optimization of the network link capacity. The developed algorithm...

  4. Performance analysis of adaptive modulation for cognitive radios with opportunistic access

    KAUST Repository

    Chen, Yunfei

    2011-06-01

    The performance of adaptive modulation for cognitive radio with opportunistic access is analyzed by considering the effects of spectrum sensing and primary user traffic for Nakagami-m fading channels. Both the adaptive continuous rate scheme and the adaptive discrete rate scheme are considered. Numerical results show that spectrum sensing and primary user traffic cause considerable degradation to the bit error rate performance of adaptive modulation in a cognitive radio system with opportunistic access to the licensed channel. They also show that primary user traffic does not affect the link spectral efficiency performance of adaptive modulation, while the spectrum sensing degrades the link spectral efficiency performance. © 2011 IEEE.

  5. NREL module energy rating methodology

    Energy Technology Data Exchange (ETDEWEB)

    Whitaker, C.; Newmiller, J.; Kroposki, B. [National Renewable Energy Laboratory, Golden, CO (United States)] [and others

    1995-11-01

    The goals of this project were to develop a tool for: evaluating one module in different climates; comparing different modules; provide a Q&D method for estimating periodic energy production; provide an achievable module rating; provide an incentive for manufacturers to optimize modules to non-STC conditions; and to have a consensus-based, NREL-sponsored activity. The approach taken was to simulate module energy for five reference days of various weather conditions. A performance model was developed.

  6. Versatile Link PLUS transceiver development

    Science.gov (United States)

    Soós, C.; Détraz, S.; Olanterä, L.; Sigaud, C.; Troska, J.; Vasey, F.; Zeiler, M.

    2017-03-01

    The Versatile Link PLUS project targets the phase II upgrades of the ATLAS and CMS experiments. It will develop a radiation resistant optical link, operating at up to 10 Gb/s in the upstream and up to 5 Gb/s in the downstream directions with a smaller footprint and higher channel count than its predecessor. A low-profile package is being developed that allows volume production at reduced costs, but which nevertheless can be configured to suit the individual channel count needs of different detectors. This paper describes the development strategies and summarizes the status of the feasibility demonstration phase of the project.

  7. Analog characterization of a Franz-Keldysh electroabsorption modulator monolithically integrated with a DFB laser

    Science.gov (United States)

    Oennegren, Jan; Svedin, Jan; Sahlen, Olof; Jansson, Mats; Alping, Arne G.

    1995-10-01

    Electroabsorption modulators (EA) are attractive components for very high speed digital links (up to 40 Gbit/s). The objective of the present work has been to evaluate the analog performance and use of a Franz Keldysh modulator (FK) monolithically integrated with a DFB laser (DFB/FK-modulator) operating at 1550 nm. This DFB/FK-modulator is a combination of a directly modulated laser diode and an external modulator in one chip. The analog performance is therefore depending on both the modulator bias voltage and DFB-laser bias current. The normal optical output characteristic from an EA-modulator has a strongly nonlinear behavior. The modulator described in this paper shows for low bias voltage and/or high laser current a linear bahavior. This linear behavior is mainly due to the hole pile-up effect at the p/i-interface of the modulator. In digital transmission system this hole pile-up effect is a disadvantage, but in an analog transmission system it can be used to achieve better analog performance. Measurements (and simulations) on the DFB/FK-modulator show that its analog performance competes well with direct modulated FP and DFB lasers, especially if the modulator is biased for optimum analog performance.

  8. Thin film module development

    Science.gov (United States)

    Jester, T.

    1985-01-01

    The design of ARCO Solar, Inc.'s Genesis G100 photovoltaic module was driven by several criteria, including environmental stability (both electrical and mechanical), consumer aesthetics, low materials costs, and manufacturing ease. The module circuitry is designed as a 12 volt battery charger, using monolithic patterning techniques on a glass superstrate. This patterning and interconnect method proves amenable to high volume, low cost production throughput, and the use of glass serves the dual role of handling ease and availability. The mechanical design of the module centers on environmental stability. Packaging of the glass superstrate circuit must provide good resistance to thermal and humidity exposure along with hi-pot insulation and hailstone impact resistance. The options considered are given. Ethylene vinyl acetate (EVA) is chosen as the pottant material for its excellent weatherability.

  9. Space Experiment Module (SEM)

    Science.gov (United States)

    Brodell, Charles L.

    1999-01-01

    The Space Experiment Module (SEM) Program is an education initiative sponsored by the National Aeronautics and Space Administration (NASA) Shuttle Small Payloads Project. The program provides nationwide educational access to space for Kindergarten through University level students. The SEM program focuses on the science of zero-gravity and microgravity. Within the program, NASA provides small containers or "modules" for students to fly experiments on the Space Shuttle. The experiments are created, designed, built, and implemented by students with teacher and/or mentor guidance. Student experiment modules are flown in a "carrier" which resides in the cargo bay of the Space Shuttle. The carrier supplies power to, and the means to control and collect data from each experiment.

  10. GREET Pretreatment Module

    Energy Technology Data Exchange (ETDEWEB)

    Adom, Felix K. [Argonne National Lab. (ANL), Argonne, IL (United States). Energy Systems Division; Dunn, Jennifer B. [Argonne National Lab. (ANL), Argonne, IL (United States). Energy Systems Division; Han, Jeongwoo [Argonne National Lab. (ANL), Argonne, IL (United States). Energy Systems Division

    2014-09-01

    A wide range of biofuels and biochemicals can be produced from cellulosic biomass via different pretreatment technologies that yield sugars. Process simulations of dilute acid and ammonia fiber expansion pretreatment processes and subsequent hydrolysis were developed in Aspen Plus for four lignocellulosic feedstocks (corn stover, miscanthus, switchgrass, and poplar). This processing yields sugars that can be subsequently converted to biofuels or biochemical. Material and energy consumption data from Aspen Plus were then compiled in a new Greenhouses Gases, Regulated Emissions, and Energy Use in Transportation (GREETTM) pretreatment module. The module estimates the cradle-to-gate fossil energy consumption (FEC) and greenhouse gas (GHG) emissions associated with producing fermentable sugars. This report documents the data and methodology used to develop this module and the cradle-to-gate FEC and GHG emissions that result from producing fermentable sugars.

  11. Quantitative velocity modulation spectroscopy

    Science.gov (United States)

    Hodges, James N.; McCall, Benjamin J.

    2016-05-01

    Velocity Modulation Spectroscopy (VMS) is arguably the most important development in the 20th century for spectroscopic study of molecular ions. For decades, interpretation of VMS lineshapes has presented challenges due to the intrinsic covariance of fit parameters including velocity modulation amplitude, linewidth, and intensity. This limitation has stifled the growth of this technique into the quantitative realm. In this work, we show that subtle changes in the lineshape can be used to help address this complexity. This allows for determination of the linewidth, intensity relative to other transitions, velocity modulation amplitude, and electric field strength in the positive column of a glow discharge. Additionally, we explain the large homogeneous component of the linewidth that has been previously described. Using this component, the ion mobility can be determined.

  12. Models for Modules

    CERN Document Server

    Troost, Jan

    2012-01-01

    We recall the structure of the indecomposable sl(2) modules in the Bernstein-Gelfand-Gelfand category O. We show that all these modules can arise as quantized phase spaces of physical models. In particular, we demonstrate in a path integral discretization how a redefined action of the sl(2) algebra over the complex numbers can glue finite dimensional and infinite dimensional highest weight representations into indecomposable wholes. Furthermore, we discuss how projective cover representations arise in the tensor product of finite dimensional and Verma modules and give explicit tensor product decomposition rules. The tensor product spaces can be realized in terms of product path integrals. Finally, we discuss relations of our results to brane quantization and cohomological calculations in string theory.

  13. Power module assembly

    Science.gov (United States)

    Campbell, Jeremy B [Torrance, CA; Newson, Steve [Redondo Beach, CA

    2011-11-15

    A power module assembly of the type suitable for deployment in a vehicular power inverter, wherein the power inverter has a grounded chassis, is provided. The power module assembly comprises a conductive base layer electrically coupled to the chassis, an insulating layer disposed on the conductive base layer, a first conductive node disposed on the insulating layer, a second conductive node disposed on the insulating layer, wherein the first and second conductive nodes are electrically isolated from each other. The power module assembly also comprises a first capacitor having a first electrode electrically connected to the conductive base layer, and a second electrode electrically connected to the first conductive node, and further comprises a second capacitor having a first electrode electrically connected to the conductive base layer, and a second electrode electrically connected to the second conductive node.

  14. Hollow dimension of modules

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    In this paper, we are interested in the following general question: Given a module Mwhich has finite hollow dimension and which has a finite collection of submodules Ki (1≤i≤n) such that M=K1+... +Kn, can we find an expression for the hollow dimension of Min terms of hollow dimensions of modules built up in some way from K1 Kn? We prove the following theorem:Let Mbe an amply supplemented module having finite hollow dimension and let Ki (1≤i≤n) be a finite collection of submodules of Msuch that M=K1+...+Kn. Then the hollow dimension h(M) of Mis the sum of the hollow dimensions of Ki (1≤i≤n) ifand only if Ki is a supplement of K1+...+Ki-1+Ki+1+...+Kn in Mfor each 1≤i≤n.

  15. Flat covers of modules

    CERN Document Server

    Xu, Jinzhong

    1996-01-01

    Since the injective envelope and projective cover were defined by Eckmann and Bas in the 1960s, they have had great influence on the development of homological algebra, ring theory and module theory. In the 1980s, Enochs introduced the flat cover and conjectured that every module has such a cover over any ring. This book provides the uniform methods and systematic treatment to study general envelopes and covers with the emphasis on the existence of flat cover. It shows that Enochs' conjecture is true for a large variety of interesting rings, and then presents the applications of the results. Readers with reasonable knowledge in rings and modules will not have difficulty in reading this book. It is suitable as a reference book and textbook for researchers and graduate students who have an interest in this field.

  16. Stirling Module Development Overview

    Science.gov (United States)

    Livingston, F. R.

    1984-01-01

    The solar parabolic dish Stirling engine electrically generating module consists of a solar collector coupled to a Stirling engine powered electrical generator. The module is designed to convert solar power to electrical power in parallel with numerous identical units coupled to an electrical utility power grid. The power conversion assembly generates up to 25 kilowatts at 480 volts potential/3 phase/alternating current. Piston rings and seals with gas leakage have not occurred, however, operator failures resulted in two burnt out receivers, while material fatigue resulted in a broken piston rod between the piston rod seal and cap seal.

  17. The Strip Module

    DEFF Research Database (Denmark)

    Pedersen, Tommy

    1996-01-01

    When the behaviour of a ship in waves is to be predicted it is convenient to have a tool which includes different approaches to the problem.The aim of this project is to develop such a tool named the strip theory module. The strip theory module will consist of submodules dependent on the I......-ship code available at the department. It will be structured as a general preprocessor mainly to determine the hydrodynamic mass and damping. A strip processor including three different theories: A linear frequency domain strip theory, a quadratic strip theory and a nonlinear time domain strip theory...

  18. Flexible programmable logic module

    Energy Technology Data Exchange (ETDEWEB)

    Robertson, Perry J. (Albuquerque, NM); Hutchinson, Robert L. (Albuquerque, NM); Pierson, Lyndon G. (Albuquerque, NM)

    2001-01-01

    The circuit module of this invention is a VME board containing a plurality of programmable logic devices (PLDs), a controlled impedance clock tree, and interconnecting buses. The PLDs are arranged to permit systolic processing of a problem by offering wide data buses and a plurality of processing nodes. The board contains a clock reference and clock distribution tree that can drive each of the PLDs with two critically timed clock references. External clock references can be used to drive additional circuit modules all operating from the same synchronous clock reference.

  19. Instant node package module

    CERN Document Server

    Ali, Juzer

    2013-01-01

    Get to grips with a new technology, understand what it is and what it can do for you, and then get to work with the most important features and tasks. A practical exploration of the lifecycle of creating node modules as well as learning all of the top features that npm has to offer.Intended for readers who want to create their first node.js modules. The programming paradigm of JavaScript is not covered so a foundation in these concepts would be beneficial.

  20. Lunar Module Illustration

    Science.gov (United States)

    1969-01-01

    This concept is a cutaway illustration of the Lunar Module (LM) with detailed callouts. The LM was a two part spacecraft. Its lower or descent stage had the landing gear, engines, and fuel needed for the landing. When the LM blasted off the Moon, the descent stage served as the launching pad for its companion ascent stage, which was also home for the two astronauts on the surface of the Moon. The LM was full of gear with which to communicate, navigate, and rendezvous. It also had its own propulsion system, and an engine to lift it off the Moon and send it on a course toward the orbiting Command Module.

  1. Pain and modulation processes

    Directory of Open Access Journals (Sweden)

    Ghaffarpoor M

    1997-08-01

    Full Text Available Pain is one of the most important and sometimes difficult problems, that patients and physicians are encountered. It may be clinically acute or chronic, acute pain has usually definite cause and favourable response to treatment. On the other hand there are difficulties in diagnosis and management of chronic pain. Peripheral and cranial nerves convey pain impulses toward central nervous system, and modulations take place at several levels. Diagnosis of different pains, including nociceptive, nerve trunk pain and deafferentation types is essential to acceptable management. In this article we review pain pathway, neurotransmitters and modulation.

  2. Novel evaluation method of TCP performance over satellite links

    Institute of Scientific and Technical Information of China (English)

    Wang Lina; Gu Xuemai

    2006-01-01

    A novel and efficient method to evaluate the transmission control protocol (TCP) performance over satellite links is presented. A TCP module is divided into three functional blocks, namely data processing, congestion control and error control. The re-established TCP module is easy to update TCP congestion control strategy or error control strategy. With the proposed analysis approach, the interactions between different congestion control and error control mechanisms, as well as the performance of various combination protocols in satellite environments have been investigated. Simulation results obtained through a series of experiments have shown that SNACK-based error control strategy can perform well with any other congestion control strategy. The best performance can be achieved by TCP New Reno congestion control strategy and SNACK-based error control strategy.

  3. Visual attention: Linking prefrontal sources to neuronal and behavioral correlates.

    Science.gov (United States)

    Clark, Kelsey; Squire, Ryan Fox; Merrikhi, Yaser; Noudoost, Behrad

    2015-09-01

    Attention is a means of flexibly selecting and enhancing a subset of sensory input based on the current behavioral goals. Numerous signatures of attention have been identified throughout the brain, and now experimenters are seeking to determine which of these signatures are causally related to the behavioral benefits of attention, and the source of these modulations within the brain. Here, we review the neural signatures of attention throughout the brain, their theoretical benefits for visual processing, and their experimental correlations with behavioral performance. We discuss the importance of measuring cue benefits as a way to distinguish between impairments on an attention task, which may instead be visual or motor impairments, and true attentional deficits. We examine evidence for various areas proposed as sources of attentional modulation within the brain, with a focus on the prefrontal cortex. Lastly, we look at studies that aim to link sources of attention to its neuronal signatures elsewhere in the brain.

  4. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... Badges Other Resources Strategic Plan Search Share Print Home » News & Events » Public Education Projects » Learn the Link - Drugs and HIV Learn ... Montgomery College Center for the Advancement of Distance Education University of ... Companies: Washington Metropolitan Area Transit Authority (WMATA) Dallas Area ...

  5. What is Linked Historical Data?

    NARCIS (Netherlands)

    Meroño-Peñuela, A.; Hoekstra, R.

    2014-01-01

    Datasets that represent historical sources are relative newcomers in the Linked Open Data (LOD) cloud. Following the standard LOD practices for publishing historical sources raises several questions: how can we distinguish between RDF graphs of primary and secondary sources? Should we treat archived

  6. What Is Linked Historical Data?

    NARCIS (Netherlands)

    Meroño-Peñuela, Albert; Hoekstra, Rinke; Janowicz, Krzysztof; Schlobach, Stefan; Lambrix, Patrick; Hyvönen, Eero

    2014-01-01

    Datasets that represent historical sources are relative new- comers in the Linked Open Data (LOD) cloud. Following the standard LOD practices for publishing historical sources raises several questions: how can we distinguish between RDF graphs of primary and secondary sources? Should we treat

  7. The intersubjective links in perversion.

    Science.gov (United States)

    Eiguer, Alberto

    2007-10-01

    The author studies the intersubjective links which the pervert maintains with analyst or partner, attempting to indicate the differences between the investments in each case. Rather than accepting that empathy towards these patients is impossible to achieve and disturbs the countertransference profoundly, it attempts to show that these difficulties may be overcome if they are reinterpreted in the light of the theory of the intersubjective link. The author examines the theories and the practice of intersubjectivity and gives a definition of his approach to the link between two subjects. He applies these ideas to the case of a sexually masochistic female patient. The countertransference is marked successively by indifference, rejection and smothering. The analysis of the analyst's dream allows the situation to evolve. Failures in primary identification can result in domination over others and utilitarianism. The author examines the place of the challenge to the 'Law' and the father (in the attempt by the patient to put a theory to the test) in order to identify the figure of the witness in the pervert's intersubjective links. The desire of the transference would be marked by the figure of the witness rather than by that of the analyst as accomplice.

  8. Property Testing on Linked Lists

    DEFF Research Database (Denmark)

    Afshani, Peyman; Matulef, Kevin; Wilkinson, Bryan Thomas

    2013-01-01

    We define a new property testing model for algorithms that do not have arbitrary query access to the input, but must instead traverse it in a manner that respects the underlying data structure in which it is stored. In particular, we consider the case when the underlying data structure is a linked...

  9. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... CDC, DHHS. Retrieved June 2012 How are Drug Abuse and HIV Related? Drug abuse and addiction have been linked with HIV/AIDS ... this regard, the role that non-injection drug abuse plays in the spread of HIV is less ...

  10. Drugs + HIV, Learn the Link

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    Full Text Available ... for contracting or transmitting HIV/AIDS or other infectious diseases. Research Reports: HIV/AIDS : Explores the link between ... Network TV Organizations: AIDS.gov AIDS Alliance for Children, Youth and Families The American Academy of Child & ...

  11. Drugs + HIV, Learn the Link

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    Full Text Available ... judgment and risky behavior. Drug abuse by any route (not just injection) can put a person at ... http://www.drugabuse.gov/news-events/public-education-projects/learn-link-drugs-hiv . 120x90 460x80 486x60 Social ...

  12. Drugs + HIV, Learn the Link

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    Full Text Available ... projects/learn-link-drugs-hiv . 120x90 460x80 486x60 Social Media Send the message to young people and ... Health Blog The NIDA Science Fair Award for Addiction Science USA Science & Engineering Festival Drug & Alcohol Chat ...

  13. Drugs + HIV, Learn the Link

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    Full Text Available ... projects/learn-link-drugs-hiv . 120x90 460x80 486x60 Social Media Send the message to young people and ... available for your use to share on your social media accounts. About the Campaign Overview The Learn ...

  14. Linking aboveground and belowground diversity

    NARCIS (Netherlands)

    Deyn, de G.B.; Putten, van der W.H.

    2005-01-01

    Aboveground and belowground species interactions drive ecosystem properties at the local scale, but it is unclear how these relationships scale-up to regional and global scales. Here, we discuss our current knowledge of aboveground and belowground diversity links from a global to a local scale. Glob

  15. Tweaking Synchronisation by Link Addition

    CERN Document Server

    Schultz, Paul; Eroglu, Deniz; Stemler, Thomas; Ávila, G Marcelo Ramírez; Rodrigues, Francisco A; Kurths, Jürgen

    2016-01-01

    Natural and man-made networks often possess locally tree-like sub-structures. Taking such tree networks as our starting point, we show how the addition of links changes the synchronization properties of the network. We focus on two different methods of link addition. The first method adds single links that create cycles of a well-defined length. Following a topological approach we introduce cycles of varying length and analyze how this feature, as well as the position in the network, alters the synchronous behaviour. We show that in particular short cycles can lead to a maximum change of the Laplacian's eigenvalue spectrum, dictating the synchronization properties of such networks. The second method connects a certain proportion of the initially unconnected nodes. We simulate dynamical systems on these network topologies, with the nodes' local dynamics being either a discrete or continuous. Here our main result is that a certain amount of additional links, with the relative position in the network being cruci...

  16. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... the News NIDA Notes Podcasts E-Newsletters Public Education Projects Contact the Press Office Meetings & Events Media ... Plan Search Share Print Home » News & Events » Public Education Projects » Learn the Link - Drugs and HIV Learn ...

  17. What is Linked Historical Data?

    NARCIS (Netherlands)

    Meroño-Peñuela, A.; Hoekstra, R.

    2014-01-01

    Datasets that represent historical sources are relative newcomers in the Linked Open Data (LOD) cloud. Following the standard LOD practices for publishing historical sources raises several questions: how can we distinguish between RDF graphs of primary and secondary sources? Should we treat archived

  18. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... Send the Message . Get the Facts What are HIV and AIDS? HIV (human immunodeficiency virus) is the virus that ... AIDS) are often linked and referred to as "HIV/AIDS." HIV can be transferred between people if an ...

  19. Is Wikipedia link structure different?

    NARCIS (Netherlands)

    Kamps, J.; Koolen, M.; Baeza-Yates, R.; Boldi, P.; Ribeiro-Neto, B.; Cambazoglu, B.B.

    2010-01-01

    In this paper, we investigate the difference between Wikipedia and Web link structure with respect to their value as indicators of the relevance of a page for a given topic of request. Our experimental evidence is from two IR test-collections: the .GOV collection used at the TREC Web tracks and the

  20. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... in the lives of young people-with the Learn the Link message. Campaign messages and materials were tested among various groups of young people, guiding the use of technology, the discussion between friends, and the importance of family. For more information, read a message ...

  1. Drugs + HIV, Learn the Link

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    Full Text Available ... projects/learn-link-drugs-hiv . 120x90 460x80 486x60 Social Media Send the message to young people and to ... available for your use to share on your social media accounts. About the Campaign Overview The Learn the ...

  2. Current Leads, Links and Buses

    CERN Document Server

    Ballarino, A

    2014-01-01

    Electrical transfer from a room temperature power source to a superconducting system is done via conventional or superconducting current leads and superconducting buses or links. The principles of optimization of these devices are presented, with emphasis on the cryogenic, electrical, and superconductor related aspects that drive choices for a system.

  3. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... HIV > Learn the Link campaign. This campaign shows teens and young adults that non-injection drug use and alcohol use can lead to poor decision making, which can result in risky sexual behaviors and HIV infection. Although the characters are fictional, ...

  4. Drugs + HIV, Learn the Link

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    Full Text Available ... learn-link-drugs-hiv . 120x90 460x80 486x60 Social Media Send the message to young people and to ... clear that injection drug abuse played a significant role in the widespread transmission of the disease. Since ...

  5. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available Skip to main content En español Researchers Medical & Health Professionals Patients & Families Parents & Educators Children & Teens Search Connect with NIDA : Facebook LinkedIn Twitter YouTube Flickr RSS Menu Home Drugs of Abuse ...

  6. What Is Linked Historical Data?

    NARCIS (Netherlands)

    Meroño-Peñuela, Albert; Hoekstra, Rinke; Janowicz, Krzysztof; Schlobach, Stefan; Lambrix, Patrick; Hyvönen, Eero

    2014-01-01

    Datasets that represent historical sources are relative new- comers in the Linked Open Data (LOD) cloud. Following the standard LOD practices for publishing historical sources raises several questions: how can we distinguish between RDF graphs of primary and secondary sources? Should we treat archiv

  7. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... HIV/AIDS, and the general public. U.S. National Library of Medicine HIV/AIDS Information : Specialized Information Services. ... link between drug abuse and HIV. Post on Facebook or Twitter ; add photos to your Flickr , Pinterest , ...

  8. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... with HIV is a key predictor of the development of AIDS. Because of their compromised immune system, ... at: http://www.drugabuse.gov/news-events/public-education-projects/learn-link-drugs-hiv . 120x90 460x80 486x60 ...

  9. Reconceptualizing the Linked Courses Model

    Science.gov (United States)

    Baxter, Mary

    2008-01-01

    To help students meet the demands of society, the University of Houston is using the framework of learning communities and constructivism to create a cross-disciplinary approach to teaching to provide media-rich thematically linked courses to engage a diverse student population. A case study investigated three semesters of thematically linked…

  10. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... projects/learn-link-drugs-hiv . 120x90 460x80 486x60 Social Media Send the message to young people and to ... available for your use to share on your social media accounts. About the Campaign Overview The Learn the ...

  11. LCSH, SKOS and Linked Data

    CERN Document Server

    Summers, Ed; Redding, Clay; Krech, Dan

    2008-01-01

    A technique for converting Library of Congress Subject Headings MARCXML to Simple Knowledge Organization System (SKOS) RDF is described. Strengths of the SKOS vocabulary are highlighted, as well as possible points for extension, and the integration of other semantic web vocabularies such as Dublin Core. An application for making the vocabulary available as linked-data on the Web is also described.

  12. New links in the family

    NARCIS (Netherlands)

    Marion Duimel; Jos de Haan

    2007-01-01

    Original title: Nieuwe links in het gezin. Virtually all families with teenagers have at least one computer with an Internet connection, often more. Teenagers spend much of their daily lives on the Internet. They use it to communicate with each other, to do their schoolwork, to meet new friends and

  13. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... Since the late 1980s, research has shown that treating drug abuse is an effective way to prevent the spread ... increasingly at risk for HIV infection through risky sexual behaviors. NIDA researchers have studied and continue to study the links between drug abuse and HIV/AIDS. In the early years of ...

  14. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... Tobacco/Nicotine and E-Cigs Other Drugs Related Topics Addiction Science Adolescent Brain Comorbidity College-Age & Young ... parties or hanging out with friends? It’s a topic you can’t ignore. Learn the Link: http:// ...

  15. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... the News NIDA Notes Podcasts E-Newsletters Public Education Projects Contact the Press Office Meetings & Events Media ... Plan Search Share Print Home » News & Events » Public Education Projects » Learn the Link - Drugs and HIV Learn ...

  16. Photovoltaic module and interlocked stack of photovoltaic modules

    Science.gov (United States)

    Wares, Brian S.

    2012-09-04

    One embodiment relates to an arrangement of photovoltaic modules configured for transportation. The arrangement includes a plurality of photovoltaic modules, each photovoltaic module including a frame having at least a top member and a bottom member. A plurality of alignment features are included on the top member of each frame, and a plurality of alignment features are included on the bottom member of each frame. Adjacent photovoltaic modules are interlocked by the alignment features on the top member of a lower module fitting together with the alignment features on the bottom member of an upper module. Other embodiments, features and aspects are also disclosed.

  17. Architecture of Platonic and Archimedean polyhedral links

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    A new methodology for understanding the construction of polyhedral links has been developed on the basis of the Platonic and Archimedean solids by using our method of the 'three-cross-curve and doubletwist-line covering'. There are five classes of polyhedral links that can be explored: the tetrahedral and truncated tetrahedral links; the hexahedral and truncated hexahedral links; the dodecahedral and truncated dodecahedral links; the truncated octahedral and icosahedral links. Our results show that the tetrahedral and truncated tetrahedral links have T symmetry; the hexahedral and truncated hexahedral links, as well as the truncated octahedral links, O symmetry; the dodecahedral and truncated dodecahedral links, as well as the truncated icosahedral links, I symmetry, respectively. This study provides further insight into the molecular design, as well as theoretical characterization, of the DNA and protein catenanes.

  18. Architecture of Platonic and Archimedean polyhedral links

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    A new methodology for understanding the construction of polyhedral links has been developed on the basis of the Platonic and Archimedean solids by using our method of the ‘three-cross-curve and dou- ble-twist-line covering’. There are five classes of polyhedral links that can be explored: the tetrahedral and truncated tetrahedral links; the hexahedral and truncated hexahedral links; the dodecahedral and truncated dodecahedral links; the truncated octahedral and icosahedral links. Our results show that the tetrahedral and truncated tetrahedral links have T symmetry; the hexahedral and truncated hexahedral links, as well as the truncated octahedral links, O symmetry; the dodecahedral and truncated dodeca- hedral links, as well as the truncated icosahedral links, I symmetry, respectively. This study provides further insight into the molecular design, as well as theoretical characterization, of the DNA and protein catenanes.

  19. Expression QTL modules as functional components underlying higher-order phenotypes.

    Directory of Open Access Journals (Sweden)

    Lei Bao

    Full Text Available Systems genetics studies often involve the mapping of numerous regulatory relations between genetic loci and expression traits. These regulatory relations form a bipartite network consisting of genetic loci and expression phenotypes. Modular network organizations may arise from the pleiotropic and polygenic regulation of gene expression. Here we analyzed the expression QTL (eQTL networks derived from expression genetic data of yeast and mouse liver and found 65 and 98 modules respectively. Computer simulation result showed that such modules rarely occurred in randomized networks with the same number of nodes and edges and same degree distribution. We also found significant within-module functional coherence. The analysis of genetic overlaps and the evidences from biomedical literature have linked some eQTL modules to physiological phenotypes. Functional coherence within the eQTL modules and genetic overlaps between the modules and physiological phenotypes suggests that eQTL modules may act as functional units underlying the higher-order phenotypes.

  20. Design of a holographic tracking module for long-range retroreflector free-space systems.

    Science.gov (United States)

    Quintana, C; Erry, G; Gomez, A; Thueux, Y; Faulkner, G E; O'Brien, D C

    2016-09-01

    Weight reduction and low power consumption are key requirements in the next generation of unmanned aerial vehicles (UAVs). To communicate with an operator, a secured link between the UAV and a ground-based station is desirable. To realize these links, retroreflecting free-space optics is potentially attractive as it offers light weight and low complexity at the UAV. However, the base station requires a high-performance tracking module to enable a steady illumination of the UAV retroreflector. In this paper, we present the design and implementation of a tracking system, which consists of coarse tracking and holographic fine tracking modules working cooperatively. Using this system, experimental field trials were carried out by mounting a multiple-quantum-well-based modulated retroreflector on a commercial UAV. A 2 Mbps optical link was achieved with a bit error rate of ∼2×10-4 at a link range of 300 m.

  1. High-Frequency Link Inverter for Fuel Cells Based on Multiple-Carrier PWM

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    HIGH-FREQUENCY (I-IF) ac link inverter topologies, with or without soft switching, have important practical advantages compared to more conventional dc link inverters in terms of isolation, size of magnetics, and other properties. It is possible to obtain these basic advantages directly in a conventional PWM inverter with trans former-coupled output, but only if the transformer can handle the low modulating frequency. HF link topologies have not been common for medium power (1 to 20kW), largely because of the number of power stages and control complexity.

  2. DC-link voltage balancing in cascaded H-Bridge converters

    Directory of Open Access Journals (Sweden)

    Lewicki Arkadiusz

    2014-09-01

    Full Text Available In this paper a DC-link voltage balancing strategy for multilevel Cascaded H-Bridge (CHB converter is proposed. Presented solution bases on optimal choice of active vector durations in Space-Vector Pulse Width Modulation (SV-PWM. It makes it possible to DC-link voltages control and to properly generate the output voltage vector in the case of DC-link voltage unbalance. Results of simulation and experimental researches on proposed control strategy are presented in the paper

  3. CERNET High Speed Data Link

    CERN Multimedia

    1975-01-01

    This card, based on a "4 slot DEC module", arbitrated the access priority of 15 datalinks of a CERNET node. Each datalinks could transfer data full duplex at 2.5 Mbit/sec over 1 Km of twisted pair (POD) cable. This was the frontier technology in 1980. The modest amount of integrated circuits was compensated by printing on the board photographs of the hardware designers, whose Belgian, Dutch and French nationality was underlined by the the short poem.

  4. A linear optical link using radiation hard VCSELs

    CERN Document Server

    Lozano-Bahilo, J; Zsenei, A

    2001-01-01

    A four-channel linear optical link has been developed to enable analogue data transmission in LHC experiments for the analogue front- end chip SCT128A. Signals from a prototype ATLAS SCT module, consisting of 12 cm long silicon strip detectors, connected to six 128 channel SCTA chips, have been transmitted at 40 MHz using the Mitel 4D469 VCSEL and matching PIN diode at a wavelength of 850 nm. Results are presented showing static and dynamic linearity, frequency response and noise. The overall performance of the complete chain is shown for /sup 241/Am spectra. (4 refs).

  5. A TDM link with channel coding and digital voice.

    Science.gov (United States)

    Jones, M. W.; Tu, K.; Harton, P. L.

    1972-01-01

    The features of a TDM (time-division multiplexed) link model are described. A PCM telemetry sequence was coded for error correction and multiplexed with a digitized voice channel. An all-digital implementation of a variable-slope delta modulation algorithm was used to digitize the voice channel. The results of extensive testing are reported. The measured coding gain and the system performance over a Gaussian channel are compared with theoretical predictions and computer simulations. Word intelligibility scores are reported as a measure of voice channel performance.

  6. High-Capacity Short-Range Optical Communication Links

    DEFF Research Database (Denmark)

    Tatarczak, Anna

    Over the last decade, we have observed a tremendous spread of end-user mobile devices. The user base of a mobile application can grow or shrink by millions per day. This situation creates a pressing need for highly scalable server infrastructure; a need nowadays satisfied through cloud computing...... offered by data centers. As the popularity of cloud computing soars, the demand for high-speed, short-range data center links grows. Vertical cavity surface emitting lasers (VCSEL) and multimode fibers (MMF) prove especially well-suited for such scenarios. VCSELs have high modulation bandwidths...

  7. Paratransit: An Instructional Module.

    Science.gov (United States)

    Scalici, Anthony

    A concept-based introduction to paratransit is provided in this instructional module for undergraduate and graduate transportation-related courses for disciplines such as engineering, business, marketing, and technology. The concept of paratransit generally refers to modes of transportation other than mass transit and solo-driven automobiles. The…

  8. An Integrated Teaching Module.

    Science.gov (United States)

    Samuel, Marie R.; Seiferth, Berniece B.

    This integrated teaching module provides elementary and junior high school teachers with a "hands-on" approach to studying the Anasazi Indian. Emphasis is on creative exploration that focuses on integrating art, music, poetry, writing, geography, dance, history, anthropology, sociology, and archaeology. Replicas of artifacts,…

  9. Modelling the Photovoltaic Module

    DEFF Research Database (Denmark)

    Katsanevakis, Markos

    2011-01-01

    This paper refers into various ways in simulation the Photovoltaic (PV) module behaviour under any combination of solar irradiation and ambient temperature. There are three different approaches presented here briefly and one of them is chosen because of its good accuracy and relatively low...

  10. Multicultural Education Module.

    Science.gov (United States)

    Campbell-Whatley, Gloria D.

    The purpose of this multicultural education module is to provide faculty, teachers, and administrators with a resource that will aid them in creating an environment that is amenable to diverse social and cultural groups within U.S. school systems. The guide identifies current resources for addressing issues with respect to cultural diversity and…

  11. Transparent solar cell module

    Science.gov (United States)

    Antonides, G. J.; Dillard, P. A.; Fritz, W. M.; Lott, D. P.

    1979-01-01

    Modified solar cell module uses high transmission glass and adhesives, and heat dissipation to boost power per unit area by 25% (9.84% efficiency based on cell area at 60 C and 100 mW/sq cm flux). Design is suited for automatic production and is potentially more cost effective.

  12. Semi-projective modules

    Directory of Open Access Journals (Sweden)

    D. Döman

    1984-03-01

    Full Text Available It is well-known that the submodules of a projective module need not be projective. In this article we investigate a certain projectivity which is preserved under the taking of submodules. This property is used to characterize hereditary rings and QF rings.

  13. ALICE silicon strip module

    CERN Multimedia

    Maximilien Brice

    2006-01-01

    This small silicon detector strip will be inserted into the inner tracking system (ITS) on the ALICE detector at CERN. This detector relies on state-of-the-art particle tracking techniques. These double-sided silicon strip modules have been designed to be as lightweight and delicate as possible as the ITS will eventually contain five square metres of these devices.

  14. Scaling: An Items Module

    Science.gov (United States)

    Tong, Ye; Kolen, Michael J.

    2010-01-01

    "Scaling" is the process of constructing a score scale that associates numbers or other ordered indicators with the performance of examinees. Scaling typically is conducted to aid users in interpreting test results. This module describes different types of raw scores and scale scores, illustrates how to incorporate various sources of…

  15. Coplanar interconnection module

    Science.gov (United States)

    Steward, R. D.; Windsor, H. F.

    1970-01-01

    Module for interconnecting a semiconductor array to external leads or components incorporates a metal external heat sink for cooling the array. Heat sink, extending down from the molded block that supports the array, is immersed in a liquid nitrogen bath which is designed to maintain the desired array temperature.

  16. Linking Europa's plume activity to tides, tectonics, and liquid water

    CERN Document Server

    Rhoden, Alyssa R; Roth, Lorenz; Retherford, Kurt

    2015-01-01

    Much of the geologic activity preserved on Europa's icy surface has been attributed to tidal deformation, mainly due to Europa's eccentric orbit. Although the surface is geologically young (30 - 80 Myr), there is little information as to whether tidally-driven surface processes are ongoing. However, a recent detection of water vapor near Europa's south pole suggests that it may be geologically active. Initial observations indicated that Europa's plume eruptions are time-variable and may be linked to its tidal cycle. Saturn's moon, Enceladus, which shares many similar traits with Europa, displays tidally-modulated plume eruptions, which bolstered this interpretation. However, additional observations of Europa at the same time in its orbit failed to yield a plume detection, casting doubt on the tidal control hypothesis. The purpose of this study is to analyze the timing of plume eruptions within the context of Europa's tidal cycle to determine whether such a link exists and examine the inferred similarities and...

  17. Generating and Executing Complex Natural Language Queries across Linked Data.

    Science.gov (United States)

    Hamon, Thierry; Mougin, Fleur; Grabar, Natalia

    2015-01-01

    With the recent and intensive research in the biomedical area, the knowledge accumulated is disseminated through various knowledge bases. Links between these knowledge bases are needed in order to use them jointly. Linked Data, SPARQL language, and interfaces in Natural Language question-answering provide interesting solutions for querying such knowledge bases. We propose a method for translating natural language questions in SPARQL queries. We use Natural Language Processing tools, semantic resources, and the RDF triples description. The method is designed on 50 questions over 3 biomedical knowledge bases, and evaluated on 27 questions. It achieves 0.78 F-measure on the test set. The method for translating natural language questions into SPARQL queries is implemented as Perl module available at http://search.cpan.org/ thhamon/RDF-NLP-SPARQLQuery.

  18. Three-phase Resonant DC-link Converter

    DEFF Research Database (Denmark)

    Munk-Nielsen, Stig

    no additional power electric components is eliminating the high voltage peaks associated with the resonant circuit. The resonant link voltage peaks are limited below 2.1 times the DC link voltages. A new principle eliminating former resonant converter stability problems are proposed, implemented and tested......The purpose of the project is to develop a three-phase resonant converter suitable for standard speed drives. The motivation for working with resonant converters is found in the problem of the standard converter type used today. In standard converter type Pulse Width Modulated-Voltage Source....... The high speed of the switches cannot be fully utilizied. By using a parallel resonant converter the switching happens at low or zero voltage which reduses switch losses. The dv/dt is controlled by the resonant circuit, and it is therefore reduced significantly. The perspective using a resonant converter...

  19. High Operation Efficiency of Semiconductor Electrooptic Modulators in Advanced Lightwave Communication Systems

    Directory of Open Access Journals (Sweden)

    Ahmed Nabih Zaki Rashed

    2012-07-01

    Full Text Available Photonic links have been proposed to transport radio frequency (RF signals over optical fiber communication systems. External optical modulation is commonly used in high performance RF photonic links. The practical use of optical fiber communication systems to transport RF signals is still limited due to high RF signal loss. In order to reduce the RF signal loss, highly efficient modulators are needed. For many applications, modulators with broad bandwidths are required. However, there are applications that require only a narrow bandwidth. For these narrow band applications, the modulation efficiency can be improved through the resonant enhancement technique at the expense of reduced transmission bandwidth. Therefore we have been investigated to get the best performance of the transmission bit rate capacity and product of different semiconductor materials based electrooptic (EO modulators over wide range of the affecting parameters.

  20. Fundamentals of spread spectrum modulation

    CERN Document Server

    Ziemer, Rodger E

    2007-01-01

    This lecture covers the fundamentals of spread spectrum modulation, which can be defined as any modulation technique that requires a transmission bandwidth much greater than the modulating signal bandwidth, independently of the bandwidth of the modulating signal. After reviewing basic digital modulation techniques, the principal forms of spread spectrum modulation are described. One of the most important components of a spread spectrum system is the spreading code, and several types and their characteristics are described. The most essential operation required at the receiver in a spread spect

  1. Lunar Module 5 mated with Spacecraft Lunar Module Adapter (SLA)

    Science.gov (United States)

    1969-01-01

    Interior view of the Kennedy Space Center's (KSC) Manned Spacecraft Operations Building showing Lunar Module 5 mated to its Spacecraft Lunar Module Adapter (SLA). LM-5 is scheduled to be flown on the Apollo 11 lunar landing mission.

  2. Link Design Rules for Cost-Effective Short-Range Radio Over Multimode Fiber Systems

    DEFF Research Database (Denmark)

    Visani, Davide; Tartarini, Giovanni; Petersen, Martin Nordal

    2010-01-01

    Referring to short-range radio over multimode fiber links, we find out important guidelines for the realization of cost-effective intensity modulated directly detected systems. Since the quality of today's connectors is considerably higher than in the past, we demonstrate that two important param...

  3. High-dynamic-range rf fiber optic link for passive antenna remoting

    Science.gov (United States)

    LaGasse, Michael J.; Thaniyavarn, Suwat

    1996-11-01

    This paper describes a bias-free, high-dynamic range, phase- modulated fiber optic link. An optical delay line filter is used for both phase demodulation and optical carrier suppression. A spur free dynamic range of 114 dB-Hz2/3 is experimentally demonstrated at a frequency of 12.5 GHz.

  4. Flexible isotopy classification of flexible links

    OpenAIRE

    Björklund, Johan

    2012-01-01

    In this paper we define and study flexible links and flexible isotopy in projective space. Flexible links are meant to capture the topological properties of real algebraic links. We classify all flexible links up to flexible isotopy using Ekholms interpretation of Viros encomplexed writhe.

  5. The importance of link evidence in Wikipedia

    NARCIS (Netherlands)

    Kamps, J.; Koolen, M.

    2008-01-01

    Wikipedia is one of the most popular information sources on the Web. The free encyclopedia is densely linked. The link structure in Wikipedia differs from the Web at large: internal links in Wikipedia are typically based on words naturally occurring in a page, and link to another semantically relate

  6. Propensity to Click on Suspicious Links

    DEFF Research Database (Denmark)

    Sudzina, Frantisek; Pavlicek, Antonin

    2017-01-01

    There already exists a certain, not huge, body of knowledge about impact of personality traits on susceptibility to phishing. But there is a gap when it comes specifically to phishing with links pretending to lead to deal sites. The paper analyzes if gender, age and personality traits influence.......1. Openness to experience was linked positively linked to responsible behavior, narcissism was negatively linked....

  7. A Q-Modulation Technique for Efficient Inductive Power Transmission.

    Science.gov (United States)

    Kiani, Mehdi; Lee, Byunghun; Yeon, Pyungwoo; Ghovanloo, Maysam

    2015-12-01

    A fully-integrated power management ASIC for efficient inductive power transmission has been presented capable of automatic load transformation using a method, called Q-modulation. Q-modulation is an adaptive scheme that offers load matching against a wide range of loading (RL ) and coupling distance (d23 ) variations in inductive links to maintain high power transfer efficiency (PTE). It is suitable for inductive powering implantable microelectronic devices (IMDs), recharging mobile electronics, and electric vehicles. In Q-modulation, the zero-crossings of the induced current in the receiver (Rx) LC-tank are detected and a low-loss switch chops the Rx LC-tank for part of the power carrier cycle to form a high-Q LC-tank and store the maximum energy, which is then transferred to RL by opening the switch. By adjusting the duty cycle (D), the loaded-Q of the Rx LC-tank can be dynamically modulated to compensate for variations in RL . A Q-modulation power management (QMPM) prototype chip was fabricated in a 0.35-μm standard CMOS process, occupying 4.8 mm(2). In a 1.45 W wireless power transfer setup, using a class-E power amplifier (PA) operating at 2 MHz, the QMPM successfully increased the inductive link PTE and the overall power efficiency by 98.5% and 120.7% at d23 = 8 cm, respectively, by compensating for 150 Ω variation in RL at D = 45%.

  8. X-linked Alport syndrome

    DEFF Research Database (Denmark)

    Jais, Jean Philippe; Knebelmann, Bertrand; Giatras, Iannis

    2003-01-01

    Alport syndrome (AS) is a type IV collagen hereditary disease characterized by progressive hematuric nephritis, hearing loss, and ocular changes. Mutations in the COL4A5 collagen gene are responsible for the more common X-linked dominant form of the disease characterized by much less severe disease...... defects developed in 75%, 28%, and 15%, respectively. The probability of developing end-stage renal disease or deafness before the age of 40 yr was 12% and 10%, respectively, in girls and women versus 90 and 80%, respectively, in boys and men. The risk of progression to end-stage renal disease appears...... to increase after the age of 60 yr in women. Because of the absence of genotype-phenotype correlation and the large intrafamilial phenotypic heterogeneity, early prognosis of the disease in X-linked Alport syndrome carriers remains moot. Risk factors for developing renal failure have been identified...

  9. X-linked Alport syndrome

    DEFF Research Database (Denmark)

    Jais, Jean Philippe; Knebelmann, Bertrand; Giatras, Iannis

    2003-01-01

    Alport syndrome (AS) is a type IV collagen hereditary disease characterized by progressive hematuric nephritis, hearing loss, and ocular changes. Mutations in the COL4A5 collagen gene are responsible for the more common X-linked dominant form of the disease characterized by much less severe disease...... in girls and women. A "European Community Alport Syndrome Concerted Action" (ECASCA) group was established to delineate the Alport syndrome phenotype in each gender and to determine genotype-phenotype correlations in a large number of families. Data concerning 329 families, 250 of them with an X...... to increase after the age of 60 yr in women. Because of the absence of genotype-phenotype correlation and the large intrafamilial phenotypic heterogeneity, early prognosis of the disease in X-linked Alport syndrome carriers remains moot. Risk factors for developing renal failure have been identified...

  10. Collagen cross linking: Current perspectives

    Directory of Open Access Journals (Sweden)

    Srinivas K Rao

    2013-01-01

    Full Text Available Keratoconus is a common ectatic disorder occurring in more than 1 in 1,000 individuals. The condition typically starts in adolescence and early adulthood. It is a disease with an uncertain cause and its progression is unpredictable, but in extreme cases, vision deteriorates and can require corneal transplant surgery. Corneal collagen cross-linking (CCL with riboflavin (C3R is a recent treatment option that can enhance the rigidity of the cornea and prevent disease progression. Since its inception, the procedure has evolved with newer instrumentation, surgical techniques, and is also now performed for expanded indications other than keratoconus. With increasing experience, newer guidelines regarding optimization of patient selection, the spectrum of complications and their management, and combination procedures are being described. This article in conjunction with the others in this issue, will try and explore the uses of collagen cross-linking (CXL in its current form.

  11. The Øresund Link

    DEFF Research Database (Denmark)

    Møller, Jacob Steen

    of hydrodynamic modelling, on line monitoring and access to all environmental information through a GIS based information system. The public attitude towards the project in general and the environmental impact in particular shifted from a very sceptical one at the beginning of the project to a very positive one......-km link across the Sound could potentially impact the water exchange between the Baltic Sea and the North Sea, and the dredging activities during construction were a threat to the local marine environment. The public interest in the environmental issues together with a pro-active environmental policy...... towards the completion of the link. It is believed that the careful use of new technology both for environmental prediction and for public information has played a major role in this development....

  12. Using turbocodes on optical links

    Directory of Open Access Journals (Sweden)

    Glenn Claes

    2006-04-01

    Full Text Available The fast evolving telecommunication world is permanently in search for faster and better communication links. On one hand, turbo codes are like a dream come true. Due to their amazing performance, they have become the reference in the word of error detecting and correcting codes. On the other hand, broadband transmission channels like optical fibres can meet the need for higher transmission velocity. In this paper therefore we will bring these two elements together and thus the performance of turbocodes on optical links will be studied. First the turbocode will be optimised throughout an individual analysis of each of its design parameters. Moreover it wil be shown that turbocodes have much better performance than the well known Reed-Solomon codes. Finally we will show that the 8Bit/10Bit code, which is required to comply with the Gigabit Ethernet standard, becomes superfluous when working with turbocodes. All tests were carried out on multimode graded-index glass fibres.

  13. X-linked Alport syndrome

    DEFF Research Database (Denmark)

    Jais, J P; Knebelmann, B; Giatras, I

    2000-01-01

    Alport syndrome (AS) is a type IV collagen hereditary disease characterized by the association of progressive hematuric nephritis, hearing loss, and, frequently, ocular changes. Mutations in the COL4A5 collagen gene are responsible for the more common X-linked dominant form of the disease....... Considerable allelic heterogeneity has been observed. A "European Community Alport Syndrome Concerted Action" has been established to delineate accurately the AS phenotype and to determine genotype-phenotype correlations in a large number of families. Data concerning 329 families, 250 of them with an X...... of age was approximately 60% in patients with missense mutations, contrary to 90% for the other types of mutations. The natural history of X-linked AS and correlations with COL4A5 mutations have been established in a large cohort of male patients. These data could be used for further evaluation...

  14. Thermally modulated biomolecule transport through nanoconfined channels.

    Science.gov (United States)

    Liu, Lei; Zhu, Lizhong

    2015-01-01

    In this work, a nanofluidic device containing both a feed cell and a permeation cell linked by nanopore arrays has been fabricated, which is employed to investigate thermally controlled biomolecular transporting properties through confined nanochannels. The ionic currents modulated by the translocations of goat antibody to human immunoglobulin G (IgG) or bovine serum albumin (BSA) are recorded and analyzed. The results suggest that the modulation effect decreases with the electrolyte concentration increasing, while the effects generated by IgG translocation are more significant than that generated by BSA translocation. More importantly, there is a maximum decreasing value in each modulated current curve with biomolecule concentration increasing for thermally induced intermolecular collision. Furthermore, the turning point for the maximum shifts to lower biomolecule concentrations with the system temperature rising (from 4°C to 45°C), and it is mainly determined by the temperature in the feed cell if the temperature difference exists in the two separated cells. These findings are expected to be valuable for the future design of novel sensing device based on nanopore and/or nanopore arrays.

  15. Linking nutrition-health-agriculture

    OpenAIRE

    2013-01-01

    Agricultural production is intimately linked with health and nutrition as a form of income, a source of food, and a cause of disease. Citing a variety of previous studies, this presentation demonstrates the complexity of the relationships among agriculture and food consumption, food safety, infection, and stunting. The authors demonstrate that increasing agricultural production does not necessarily result in improved nutrition: Although more food may be available, this greater yield may suppl...

  16. How expensive is link utilization?

    OpenAIRE

    Stanojević, Rade; Shorten, Robert

    2007-01-01

    Understanding the relationship between queueing delays and link utilization for general traffic conditions is an important open problem in networking research. Difficulties in understanding this relationship stem from the fact that it depends on the complex nature of arriving traffic and the problems associated with modelling such traffic. Existing AQM schemes achieve a "low delay" and "high utilization" by responding early to congestion without considering the exact relationship betwee...

  17. Managing Your Team's Weakest Link.

    Science.gov (United States)

    Hills, Laura

    2015-01-01

    Do you have a poor-performing employee on your medical practice team? If so, you're not alone. Unfortunately, this is a problem that many medical practice managers face. This article describes the best strategies for managing your team's weakest link. It explores common yet very difficult circumstances that cause low employee performance and that test the patience, heart, and skills of a practice manager. It guides readers through a process of self-discovery to determine whether their negative biases or grudges may be causing employees to perform poorly. It suggests several possible other reasons for weak employee performance, including problems with the job, practice, leadership, communication, and fit between the employee and the job. This article also suggests the best strategy for communicating concerns about performance to the weakest-link employee. It offers guidance to practice managers about protecting their time and energy when handling a poor performer. It provides a simple formula for calculating the cost of a low-performing employee, 10 possible personal reasons for the employee's poor work performance, specific questions to ask to uncover the reasons for poor performance, and an eight-rule strategy for confronting poor performance effectively. Finally, this article offers practice managers a practical strategy for handling resistance from their weakest link, illustrated with a sample dialogue.

  18. The Øresund Link

    DEFF Research Database (Denmark)

    Møller, Jacob Steen

    "Øresundsbron" is the combined bridge and tunnel connecting Denmark and Sweden adjacent to Copenhagen. Øresundsbron was built and is operated by a consortium owned jointly by the Danish and Swedish states. The Link was inaugurated 1 July 2000 by the Queen of Denmark and the King of Sweden. The 16...... towards the completion of the link. It is believed that the careful use of new technology both for environmental prediction and for public information has played a major role in this development.......-km link across the Sound could potentially impact the water exchange between the Baltic Sea and the North Sea, and the dredging activities during construction were a threat to the local marine environment. The public interest in the environmental issues together with a pro-active environmental policy...... of hydrodynamic modelling, on line monitoring and access to all environmental information through a GIS based information system. The public attitude towards the project in general and the environmental impact in particular shifted from a very sceptical one at the beginning of the project to a very positive one...

  19. Switching speed limitations of high power IGBT modules

    DEFF Research Database (Denmark)

    Incau, Bogdan Ioan; Trintis, Ionut; Munk-Nielsen, Stig

    2015-01-01

    In this paper the switching speed limits of high power IGBT modules are investigated. The limitation of turn-on and turn-off switching speeds of the IGBTs are experimentally detected in a pulse tester. Different dc-bus stray inductances are considered, as well as the worst case scenario...... for the blocking dc-link voltage. Switching losses are analyzed upon a considerable variation of resistor value from turn-on gate driver side. Short circuit operations are investigated along with safe operating area for entire module to validate electrical capabilities under extreme conditions....

  20. Modulation in voluntary neural drive in relation to muscle soreness

    OpenAIRE

    Racinais, S.; Bringard, A.; Puchaux, K.; Noakes, T D; Perrey, S.

    2007-01-01

    The aim of this study was to investigate whether (1) spinal modulation would change after non-exhausting eccentric exercise of the plantar flexor muscles that produced muscle soreness and (2) central modulation of the motor command would be linked to the development of muscle soreness. Ten healthy subjects volunteered to perform a single bout of backward downhill walking exercise (duration 30 min, velocity 1 ms−1, negative grade −25%, load 12% of body weight). Neuromuscular test sessions [H-r...