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Sample records for modern microscopical methods

  1. Theory and use of modern microscopical methods with applications to studies of wetlands microbial community dynamics. Final performance reports

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-31

    Funds were granted to the University of Southwestern Louisiana to coordinate and offer a summer enhancement institute for science teachers. Following are highlights from that institute: (1) 20 teachers from Louisiana attended the institute as students; (2) institute faculty included staff members from USL`s Departments of Biology, Mathematics, and Education and 3 principal scientists plus technicians from the Southern Science Center; (3) the institute began June 5, 1995 and ended June 30, 1995, and it featured daily lectures, laboratory exercises, examinations, and field trips--assignments for students included journal keeping, lesson plan development, and presentations, the student`s journal entries proved valuable for evaluating institute activities, students received copies of lesson plans developed at the institute, videos entitled ``Pond Life Diversity`` and ``Chesapeake: The Twilight Estuary,`` a guide to ``Free-lining Freshwater Protozoa,`` a graphing calculator, 2 x 2 slide set of pond life, software or hardware (selected by the teacher to meet specific needs), a field manual for water quality monitoring laboratory exercises (Project Green), and a book on Benchmarks for Science Literacy; (4) follow-up measures included the following--a newsletter disseminated by USL but written with teacher input; making equipment (such as a trinocular compound microscope and video monitor) and materials and supplies available to the teachers and their students in the classroom; and mentoring between USL and SSC staff and the teachers during the school year. Attached to this report are copies of the institute agenda and lesson plans developed in the institute.

  2. Modern Reduction Methods

    CERN Document Server

    Andersson, Pher G

    2008-01-01

    With its comprehensive overview of modern reduction methods, this book features high quality contributions allowing readers to find reliable solutions quickly and easily. The monograph treats the reduction of carbonyles, alkenes, imines and alkynes, as well as reductive aminations and cross and heck couplings, before finishing off with sections on kinetic resolutions and hydrogenolysis. An indispensable lab companion for every chemist.

  3. Methods in Modern Biophysics

    CERN Document Server

    Nölting, Bengt

    2006-01-01

    Incorporating recent dramatic advances, this textbook presents a fresh and timely introduction to modern biophysical methods. An array of new, faster and higher-power biophysical methods now enables scientists to examine the mysteries of life at a molecular level. This innovative text surveys and explains the ten key biophysical methods, including those related to biophysical nanotechnology, scanning probe microscopy, X-ray crystallography, ion mobility spectrometry, mass spectrometry, proteomics, and protein folding and structure. Incorporating much information previously unavailable in tutorial form, Nölting employs worked examples and 267 illustrations to fully detail the techniques and their underlying mechanisms. Methods in Modern Biophysics is written for advanced undergraduate and graduate students, postdocs, researchers, lecturers and professors in biophysics, biochemistry and related fields. Special features in the 2nd edition: • Illustrates the high-resolution methods for ultrashort-living protei...

  4. Methods in Modern Biophysics

    CERN Document Server

    Nölting, Bengt

    2010-01-01

    Incorporating recent dramatic advances, this textbook presents a fresh and timely introduction to modern biophysical methods. An array of new, faster and higher-power biophysical methods now enables scientists to examine the mysteries of life at a molecular level. This innovative text surveys and explains the ten key biophysical methods, including those related to biophysical nanotechnology, scanning probe microscopy, X-ray crystallography, ion mobility spectrometry, mass spectrometry, proteomics, and protein folding and structure. Incorporating much information previously unavailable in tutorial form, Nölting employs worked examples and about 270 illustrations to fully detail the techniques and their underlying mechanisms. Methods in Modern Biophysics is written for advanced undergraduate and graduate students, postdocs, researchers, lecturers, and professors in biophysics, biochemistry and related fields. Special features in the 3rd edition: Introduces rapid partial protein ladder sequencing - an important...

  5. Scanning tunneling microscope nanoetching method

    Science.gov (United States)

    Li, Yun-Zhong; Reifenberger, Ronald G.; Andres, Ronald P.

    1990-01-01

    A method is described for forming uniform nanometer sized depressions on the surface of a conducting substrate. A tunneling tip is used to apply tunneling current density sufficient to vaporize a localized area of the substrate surface. The resulting depressions or craters in the substrate surface can be formed in information encoding patterns readable with a scanning tunneling microscope.

  6. Microscope and method of use

    Science.gov (United States)

    Bongianni, Wayne L.

    1984-01-01

    A method and apparatus for electronically focusing and electronically scanning microscopic specimens are given. In the invention, visual images of even moving, living, opaque specimens can be acoustically obtained and viewed with virtually no time needed for processing (i.e., real time processing is used). And planar samples are not required. The specimens (if planar) need not be moved during scanning, although it will be desirable and possible to move or rotate nonplanar specimens (e.g., laser fusion targets) against the lens of the apparatus. No coupling fluid is needed, so specimens need not be wetted. A phase acoustic microscope is also made from the basic microscope components together with electronic mixers.

  7. Methods of modern mathematical physics

    CERN Document Server

    Reed, Michael

    1980-01-01

    This book is the first of a multivolume series devoted to an exposition of functional analysis methods in modern mathematical physics. It describes the fundamental principles of functional analysis and is essentially self-contained, although there are occasional references to later volumes. We have included a few applications when we thought that they would provide motivation for the reader. Later volumes describe various advanced topics in functional analysis and give numerous applications in classical physics, modern physics, and partial differential equations.

  8. Quantitative properties of clustering within modern microscopic nuclear models

    International Nuclear Information System (INIS)

    Volya, A.; Tchuvil’sky, Yu. M.

    2016-01-01

    A method for studying cluster spectroscopic properties of nuclear fragmentation, such as spectroscopic amplitudes, cluster form factors, and spectroscopic factors, is developed on the basis of modern precision nuclear models that take into account the mixing of large-scale shell-model configurations. Alpha-cluster channels are considered as an example. A mathematical proof of the need for taking into account the channel-wave-function renormalization generated by exchange terms of the antisymmetrization operator (Fliessbach effect) is given. Examples where this effect is confirmed by a high quality of the description of experimental data are presented. By and large, the method in question extends substantially the possibilities for studying clustering phenomena in nuclei and for improving the quality of their description.

  9. Microscopic nuclear structure calculations with modern meson-exchange potentials

    International Nuclear Information System (INIS)

    Hjort-Jensen, M.; Osnes, E.; Muether, H.; Schmid, K.W.; Kuo, T.T.S.

    1990-07-01

    The report presents the results of microscopic nuclear shell-model calculations using three different nucleon-nucleon potentials. These are the phenomenological Reid-Soft-Core potential and the meson-exchange potentials of the Paris and the Bonn groups. It is found that the Bonn potential yields sd-shell matrix elements which are more attractive than those obtained with the Reid or the Paris potentials. The harmonic-oscillator matrix elements of the Bonn potential are also in better agreement with the empirically derived matrix elements of Wildenthal. The implications are discussed. 27 refs., 4 figs., 1 tab

  10. [Modern methods of diagnosis dyslipidemia ].

    Science.gov (United States)

    Sukhorukov, V N; Karagodin, V P; Orekhov, A N

    2016-01-01

    Dyslipidemia is abnormalities of lipid and lipoprotein metabolism. Most dyslipidemias are hyperlipidemias; that is an abnormally high level of lipids and/or lipoproteins in the blood. Lipid and lipoprotein abnormalities are common in the general population, and are regarded as a modifiable risk factor for cardiovascular disease due to their influence on atherosclerosis. Primary dyslipidemia is usually due to genetic causes, while secondary dyslipidemia arises due to other underlying causes such as diabetes mellitus. Thus, dyslipidemia is an important factor in the development of atherosclerosis and cardiovascular diseases therefore, it is important to diagnose it in time. This review focuses on the modern methods of diagnosis of dyslipidemia.

  11. NOMAD: a nodal microscopic analysis method for nuclear fuel depletion

    International Nuclear Information System (INIS)

    Rajic, H.L.; Ougouag, A.M.

    1987-01-01

    Recently developed assembly homogenization techniques made possible very efficient global burnup calculations based on modern nodal methods. There are two possible ways of modeling the global depletion process: macroscopic and microscopic depletion models. Using a microscopic global depletion approach NOMAD (NOdal Microscopic Analysis Method for Nuclear Fuel Depletion), a multigroup, two- and three-dimensional, multicycle depletion code was devised. The code uses the ILLICO nodal diffusion model. The formalism of the ILLICO methodology is extended to treat changes in the macroscopic cross sections during a depletion cycle without recomputing the coupling coefficients. This results in a computationally very efficient method. The code was tested against a well-known depletion benchmark problem. In this problem a two-dimensional pressurized water reactor is depleted through two cycles. Both cycles were run with 1 x 1 and 2 x 2 nodes per assembly. It is obvious that the one node per assembly solution gives unacceptable results while the 2 x 2 solution gives relative power errors consistently below 2%

  12. Modern teaching methods in economic subjects.

    OpenAIRE

    Maxa, Radek

    2014-01-01

    The main objective of this thesis is a comprehensive assessment of the practical usability and effectiveness of modern activating teaching methods in economic subjects in fulfilling the RVP economics and business and RVP Business Academy in comparison with traditional (standard) methods. To achieve this goal, a systematic clarification and evaluation of key elements of the choice of adequate methods of teaching, presentation and comparison of traditional, modern activating and comprehensive t...

  13. Modern methods of thyroid diagnosis

    Energy Technology Data Exchange (ETDEWEB)

    Hehrmann, R

    1980-11-01

    An attempt is made to provide a systematic general view at the diagnostical methods and facilities which nowadays are applied in the case of thyroid diseases. The reasonable and accurate application of the various methods possible is of decisive importance for the thyroid diagnostics. This planned application requires exact knowledge of the case history and of the findings as well as knowledge of the preconditions, the advantages and disadvantages of and the possible errors in the methods applied. Proposals and guiding lines for a planned step-by-step application of methods of diagnosing thyroid diseases were published by the Section Thyroid Society for Endocrinology in Wiesbaden in December 1978. For step-by-step diagnostics of thyroid diseaeses, these publications may be of help.

  14. Quantitative methods for the analysis of electron microscope images

    DEFF Research Database (Denmark)

    Skands, Peter Ulrik Vallø

    1996-01-01

    The topic of this thesis is an general introduction to quantitative methods for the analysis of digital microscope images. The images presented are primarily been acquired from Scanning Electron Microscopes (SEM) and interfermeter microscopes (IFM). The topic is approached though several examples...... foundation of the thesis fall in the areas of: 1) Mathematical Morphology; 2) Distance transforms and applications; and 3) Fractal geometry. Image analysis opens in general the possibility of a quantitative and statistical well founded measurement of digital microscope images. Herein lies also the conditions...

  15. Microscopic Identification of Prokaryotes in Modern and Ancient Halite, Saline Valley and Death Valley, California

    Science.gov (United States)

    Schubert, Brian A.; Lowenstein, Tim K.; Timofeeff, Michael N.

    2009-06-01

    Primary fluid inclusions in halite crystallized in Saline Valley, California, in 1980, 2004-2005, and 2007, contain rod- and coccoid-shaped microparticles the same size and morphology as archaea and bacteria living in modern brines. Primary fluid inclusions from a well-dated (0-100,000 years), 90 m long salt core from Badwater Basin, Death Valley, California, also contain microparticles, here interpreted as halophilic and halotolerant prokaryotes. Prokaryotes are distinguished from crystals on the basis of morphology, optical properties (birefringence), and uniformity of size. Electron micrographs of microparticles from filtered modern brine (Saline Valley), dissolved modern halite crystals (Saline Valley), and dissolved ancient halite crystals (Death Valley) support in situ microscopic observations that prokaryotes are present in fluid inclusions in ancient halite. In the Death Valley salt core, prokaryotes in fluid inclusions occur almost exclusively in halite precipitated in perennial saline lakes 10,000 to 35,000 years ago. This suggests that trapping and preservation of prokaryotes in fluid inclusions is influenced by the surface environment in which the halite originally precipitated. In all cases, prokaryotes in fluid inclusions in halite from the Death Valley salt core are miniaturized (<1 μm diameter cocci, <2.5 μm long, very rare rod shapes), which supports interpretations that the prokaryotes are indigenous to the halite and starvation survival may be the normal response of some prokaryotes to entrapment in fluid inclusions for millennia. These results reinforce the view that fluid inclusions in halite and possibly other evaporites are important repositories of microbial life and should be carefully examined in the search for ancient microorganisms on Earth, Mars, and elsewhere in the Solar System.

  16. MODERN METHODS OF FOOD INTOLERANCE TESTING

    Directory of Open Access Journals (Sweden)

    M. Yu. Rosensteyn

    2016-01-01

    Full Text Available Аn analytical review of modern methods of food intolerance diagnostics based on interpretation of markers used in the various tests is рresented. It is shown that tests based on observation of the reaction of specific antibodies of the immune system to food antigens tested, are the most accurate, reliable and representative for the diagnosis of food intolerance.

  17. Diabetic osteoarthropathy: modern methods of therapy

    Directory of Open Access Journals (Sweden)

    Irina Nikolaevna Ul'yanova

    2010-12-01

    Full Text Available This paper is focused on the main aspects of pathogenesis of diabetic osteoarthropathy (DOAP underlain by motor and sensory neuropathies, injuries(including microfractures and joint disintegration, and inflammation accompanied by enhanced cytokine expression. The role of osteopenia andbone resorption-formation decoupling at different stages of DOAP is discussed. Modern methods of DOAP treatment are considered with special referenceto immobilization, drug therapy, surgical and orthopedic care

  18. Microscopic approach to the generator coordinate method

    International Nuclear Information System (INIS)

    Haider, Q.; Gogny, D.; Weiss, M.S.

    1989-01-01

    In this paper, we solve different theoretical problems associated with the calculation of the kernel occurring in the Hill-Wheeler integral equations within the framework of generator coordinate method. In particular, we extend the Wick's theorem to nonorthogonal Bogoliubov states. Expressions for the overlap between Bogoliubov states and for the generalized density matrix are also derived. These expressions are valid even when using an incomplete basis, as in the case of actual calculations. Finally, the Hill-Wheeler formalism is developed for a finite range interaction and the Skyrme force, and evaluated for the latter. 20 refs., 1 fig., 4 tabs

  19. A method for fast automated microscope image stitching.

    Science.gov (United States)

    Yang, Fan; Deng, Zhen-Sheng; Fan, Qiu-Hong

    2013-05-01

    Image stitching is an important technology to produce a panorama or larger image by combining several images with overlapped areas. In many biomedical researches, image stitching is highly desirable to acquire a panoramic image which represents large areas of certain structures or whole sections, while retaining microscopic resolution. In this study, we develop a fast normal light microscope image stitching algorithm based on feature extraction. At first, an algorithm of scale-space reconstruction of speeded-up robust features (SURF) was proposed to extract features from the images to be stitched with a short time and higher repeatability. Then, the histogram equalization (HE) method was employed to preprocess the images to enhance their contrast for extracting more features. Thirdly, the rough overlapping zones of the images preprocessed were calculated by phase correlation, and the improved SURF was used to extract the image features in the rough overlapping areas. Fourthly, the features were corresponded by matching algorithm and the transformation parameters were estimated, then the images were blended seamlessly. Finally, this procedure was applied to stitch normal light microscope images to verify its validity. Our experimental results demonstrate that the improved SURF algorithm is very robust to viewpoint, illumination, blur, rotation and zoom of the images and our method is able to stitch microscope images automatically with high precision and high speed. Also, the method proposed in this paper is applicable to registration and stitching of common images as well as stitching the microscope images in the field of virtual microscope for the purpose of observing, exchanging, saving, and establishing a database of microscope images. Copyright © 2013 Elsevier Ltd. All rights reserved.

  20. Improved coating and fixation methods for scanning electron microscope autoradiography

    International Nuclear Information System (INIS)

    Weiss, R.L.

    1984-01-01

    A simple apparatus for emulsion coating is described. The apparatus is inexpensive and easily assembled in a standard glass shop. Emulsion coating for scanning electron microscope autoradiography with this apparatus consistently yields uniform layers. When used in conjunction with newly described fixation methods, this new approach produces reliable autoradiographs of undamaged specimens

  1. MODERN METHODS OF REASONABLE PRODUCT SUPPLY

    Directory of Open Access Journals (Sweden)

    Anna Kulik

    2016-11-01

    Full Text Available Thesis objective is to study modern methods of product supply with the purpose to determine optimal ways for their rationalization. Since the use of reasonable practices, taking into account external and internal factors under the specific conditions of product moving from the supplier to the buyer, makes the process of product supply economically viable, i.e., low costs for product transportation, ensures fast moving products, their safety and, ultimately, results in reduction of the costs of product disposal. Methodology. The study is based on theoretical methods to study this problem. System analysis method and simulation of the ways to improve were also used in the study. Results. Addressing these issues, the concept, form and stages of product supply process organization depending on the type of product have been studied; product supply management methods based on logistics concept of “demand response”. Practical significance. Optimization of the principles and methods of product supply, factors affecting its organization will, in practice, contribute to the development of reasonable product delivery systems featured with economic efficiency of advanced technologies of product supply. Value/ originality. The analyzed methods of product supply management based on logistics concept of “demand response” can ensure maximum reduction of response time to the changes in demand by rapid stocktaking at those points of the market where the demand is expected to increase, which will allow to reduce the costs of bringing the product to the consumer.

  2. Apparatus and methods for controlling electron microscope stages

    Science.gov (United States)

    Duden, Thomas

    2015-08-11

    Methods and apparatus for generating an image of a specimen with a microscope (e.g., TEM) are disclosed. In one aspect, the microscope may generally include a beam generator, a stage, a detector, and an image generator. A plurality of crystal parameters, which describe a plurality of properties of a crystal sample, are received. In a display associated with the microscope, an interactive control sphere based at least in part on the received crystal parameters and that is rotatable by a user to different sphere orientations is presented. The sphere includes a plurality of stage coordinates that correspond to a plurality of positions of the stage and a plurality of crystallographic pole coordinates that correspond to a plurality of polar orientations of the crystal sample. Movement of the sphere causes movement of the stage, wherein the stage coordinates move in conjunction with the crystallographic coordinates represented by pole positions so as to show a relationship between stage positions and the pole positions.

  3. Modern methods in analytical acoustics lecture notes

    CERN Document Server

    Crighton, D G; Williams, J E Ffowcs; Heckl, M; Leppington, F G

    1992-01-01

    Modern Methods in Analytical Acoustics considers topics fundamental to the understanding of noise, vibration and fluid mechanisms. The series of lectures on which this material is based began by some twenty five years ago and has been developed and expanded ever since. Acknowledged experts in the field have given this course many times in Europe and the USA. Although the scope of the course has widened considerably, the primary aim of teaching analytical techniques of acoustics alongside specific areas of wave motion and unsteady fluid mechanisms remains. The distinguished authors of this volume are drawn from Departments of Acoustics, Engineering of Applied Mathematics in Berlin, Cambridge and London. Their intention is to reach a wider audience of all those concerned with acoustic analysis than has been able to attend the course.

  4. Microscopic methods in analysis of submicron phospholipid dispersions

    Directory of Open Access Journals (Sweden)

    Płaczek Marcin

    2016-03-01

    Full Text Available Microscopy belongs to the group of tests, used in pharmaceutical technology, that despite the lapse of time and the development of new analytical methods, still remain irreplaceable for the characterization of dispersed drug dosage forms (e.g., suspensions and emulsions. To obtain complete description of a specific drug formulation, such as parenteral colloidal products, a combination of different microscopic techniques is sometimes required. Electron microscopy methods are the most useful ones; however, even such basic methods as optical microscopy may be helpful for determination of some properties of a sample. The publication explicates the most popular microscopical techniques used nowadays for characterization of the morphology of nanoparticles suspended in pharmaceutical formulations; ad vantages and disadvantages of these methods are also discussed. Parenteral submicron formulations containing lecithin or a particular phospholipid were chosen as examples.

  5. Hydrobalneological methods in modern medical treatment

    Directory of Open Access Journals (Sweden)

    Włodzisław Kuliński

    2015-03-01

    Full Text Available Introduction: Therapeutic methods combining balneology and hydrotherapy have been used in treatment and prevention for a long time. Their influence on the skin, based on mechanical, thermal, and hydrostatic stimuli, results in a reaction of the internal organs as well as the whole body. The most important effects of such procedures are changes within the cardiovascular system. Aim of the research: The use of hydrobalneological methods in modern medical treatment. Material and methods : The analysis focused on the influence of water jets at alternating temperatures in the treatment of functional cardiovascular disturbances with the use of non-invasive methods of autonomic nervous system function work-up based on the analysis of heart rate variability. The effect of the jets on heart rate and blood pressure was observed in 50 patients with first-degree hypertension, which was accompanied by radioelectrocardiographic (RECG assessment of the influence of underwater massage and carbonic acid baths on the cardiovascular system in patients undergoing these procedures due to Da Costa’s syndrome. Results : Water jets at alternating temperatures successfully modulate the tension within the autonomic nervous system and stimulate its parasympathetic part. Underwater massage is a gentle procedure and does not cause significant changes in heart rate and RECG tracing. Carbonic acid baths decrease autonomic nervous system excitability. Conclusions: The study results show a possibility of regulating autonomic nervous system function with the use of selected balneological and hydrotherapeutic methods, and thus influencing the functional level of the human body which is most appropriate for the requirements created by the internal and external environment of the body.

  6. Application of the microscopic method in cutaneous leishmania diagnosis

    Directory of Open Access Journals (Sweden)

    Mohammed Wael Daboul

    2011-10-01

    Full Text Available Introduction: Cutaneous leishmania is spreading fast. This study aims at developing the microscopic method to achieve a full detection of all positive cases of leishmania.Methods: 50 human cases have been studied by applying microscopic smears stained with Wright stain. Microscopic photos were taken for the presumed unfamiliar figures.Results: Mononuclear cells with tails are present at a rate of (98%. They are associated with Leishman Donovan (LD bodies in 50% of the cases. The polygonal figures and the spherical forms are present at the same rate (60% and are associated with LD bodies in 24% of the cases. The small promastigote like forms are seen at a rate of (76% and are associated with LD bodies in 26% of the cases. The giant promastigotes like forms are present in (80% of the cases and are associated with LD bodies in 28% of the cases. Candle flame forms are present in (40% of the cases and are associated with the LD bodies in 21% of the cases.Discussion: It is applicable to use those discovered figures in diagnosing cutaneous leishmania.

  7. Use of results from microscopic methods in optical model calculations

    International Nuclear Information System (INIS)

    Lagrange, C.

    1985-11-01

    A concept of vectorization for coupled-channel programs based upon conventional methods is first presented. This has been implanted in our program for its use on the CRAY-1 computer. In a second part we investigate the capabilities of a semi-microscopic optical model involving fewer adjustable parameters than phenomenological ones. The two main ingredients of our calculations are, for spherical or well-deformed nuclei, the microscopic optical-model calculations of Jeukenne, Lejeune and Mahaux and nuclear densities from Hartree-Fock-Bogoliubov calculations using the density-dependent force D1. For transitional nuclei deformation-dependent nuclear structure wave functions are employed to weigh the scattering potentials for different shapes and channels [fr

  8. Radar Scan Methods in Modern Multifunctional Radars

    Directory of Open Access Journals (Sweden)

    V. N. Skosyrev

    2014-01-01

    Full Text Available Considered urgent task of organizing the review space in modern multifunctional radar systems shall review the space in a wide range of elevation angles from minus 5 to 60-80 degrees and 360 degrees azimuth. MfRLS this type should provide an overview of the zone for a limited time (2-3 sec, detecting a wide range of subtle high and low-flying targets. The latter circumstance requires the organization to select targets against the background of reflections from the underlying surface and local objects (MP. When providing an overview of the space taken into account the need to increase not only the noise immunity, and survivability.Two variants of the review of space in the elevation plane in the solid-state AESA radar. In the first case the overview space narrow beam by one beam. In the second - the transfer of DNA is formed, covering the whole sector of responsibility in elevation and at the reception beam is formed in spetsvychislitele (CB as a result of the signal processing of digitized after emitters antenna web. The estimations of the parameters specific to the multifunction radar SAM air and missile defense. It is shown that in a number of practically important cases, preference should be given clearly one of the methods described review of space.The functional scheme with AESA radar for both variants of the review. Necessary to analyze their differences. Contains the problem of increasing the cost of MfRLS with digital beamforming DNA with increasing bandwidth probing signal being processed.Noted drawbacks of MfRLS with digital beamforming beam. Including: reduced accuracy of the coordinates at low elevation angles, the complexity of the organization of thermal regime of the solid element base using quasi-continuous signal with a low duty cycle. Shows their fundamentally unavoidable in the steppe and desert areas with uneven terrain (Kazakhstan, China, the Middle East.It is shown that for MfRLS working in strong clutter, more preferably

  9. Microscopic methods for the interactions between complex nuclei

    International Nuclear Information System (INIS)

    Ikeda, Kiyomi; Tamagaki, Ryozo; Saito, Sakae; Horiuchi, Hisashi; Tohsaki-Suzuki, Akihiro.

    1978-01-01

    Microscopic study on composite-particle interaction performed in Japan is described in this paper. In chapter 1, brief historical description of the study is presented. In chapter 2, the theory of resonating group method (RGM) for describing microscopically the interaction between nuclei (clusters) is reviewed, and formulation on the description is presented. It is shown that the generator coordinate method (GCM) is a useful one for the description of interaction between shell model clusters, and that the kernels in the RGM are easily obtained from those of the GCM. The inter-cluster interaction can be well described by the orthogonality condition model (OCM). In chapter 3, the calculational procedures for the kernels of GCN, RGM and OCM and some properties related to their calculation are discussed. The GCM kernels for various types of systems are treated. The RGM kernels are evaluated by the integral transformation of GCM kernels. The problems related to the RGM norm kernel (RGM-NK) are discussed. The projection operator onto the Pauli-allowed state in OCM is obtained directly from the solution of the eigenvalue problem of RGM-NK. In chapter 4, the exchange kernels due to the antisymmetrization are derived in analytical way with the symbolical use of computer memory by taking the α + O 16 system as a typical example. New algorisms for deriving analytically the generator coordinate kernel (GCM kernel) are presented. In chapter 5, precise generalization of the Kohn-Hulthen-Kato variational method for scattering matrix is made for the purpose of microscopic study of reactions between complex nuclei with many channels coupled. (Kato, T.)

  10. Modern

    Directory of Open Access Journals (Sweden)

    A.V. Bagrov

    2014-06-01

    Full Text Available The article gives an overview of the most important problems of modern meteoric astronomy and briefly describes ways and methods of their solutions. Particular attention is paid to the construction and arrangement of meteoric video cameras intended for registration of the meteoric phenomena as the main method of obtaining reliable and objective observational data on the basis of which the solution of the described tasks is possible.

  11. Digital phase-shifting atomic force microscope Moire method

    International Nuclear Information System (INIS)

    Liu Chiaming; Chen Lienwen

    2005-01-01

    In this study, the digital atomic force microscope (AFM) Moire method with phase-shifting technology is established to measure the in-plane displacement and strain fields. The Moire pattern is generated by the interference between the specimen grating and the virtual reference grating formed by digital image processes. The overlapped image is filtered by two-dimensional wavelet transformation to obtain the clear interference Moire patterns. The four-step phase-shifting method is realized by translating the phase of the virtual reference grating from 0 to 2π. The principle of the digital AFM Moire method and the phase-shifting technology are described in detail. Experimental results show that this method is convenient to use and efficient in realizing the microscale measurement

  12. Modern Instrumental Methods in Forensic Toxicology*

    Science.gov (United States)

    Smith, Michael L.; Vorce, Shawn P.; Holler, Justin M.; Shimomura, Eric; Magluilo, Joe; Jacobs, Aaron J.; Huestis, Marilyn A.

    2009-01-01

    This article reviews modern analytical instrumentation in forensic toxicology for identification and quantification of drugs and toxins in biological fluids and tissues. A brief description of the theory and inherent strengths and limitations of each methodology is included. The focus is on new technologies that address current analytical limitations. A goal of this review is to encourage innovations to improve our technological capabilities and to encourage use of these analytical techniques in forensic toxicology practice. PMID:17579968

  13. A comparative analysis of microscopic alterations in modern and ancient undecalcified and decalcified dry bones.

    Science.gov (United States)

    Caruso, Valentina; Cummaudo, Marco; Maderna, Emanuela; Cappella, Annalisa; Caudullo, Giorgio; Scarpulla, Valentina; Cattaneo, Cristina

    2018-02-01

    The present study aims to evaluate the preservation of the microstructure of skeletal remains collected from four different known burial sites (archaeological and contemporary). Histological analysis on undecalcified and decalcified thin sections was performed in order to assess which of the two techniques is more affected by taphonomic insults. A histological analysis was performed on both undecalcified and decalcified thin sections of 40 long bones and the degree of diagenetic change was evaluated using transmitted and polarized light microscopy according to the Oxford Histological Index (OHI). In order to test the optical behavior of bone tissue, thin sections were observed by polarized light microscopy and the intensity of birefringence was evaluated. The more ancient samples are generally characterized by a low OHI (0-1) with extensive microscopic focal destruction; recent samples exhibited a better preservation of bone micromorphology. When comparing undecalcified to decalcified thin sections, the latter showed an amelioration in the conservation of microscopic structure. As regards the birefringence, it was very low in all the undecalcified thin sections, whereas decalcification process seems to improve its visibility. The preservation of the bone microscopic structure appears to be influenced not only by age, but also by the burial context. Undecalcified bones appear to be more affected by taphonomical alterations, probably because of the thickness of the thin sections; on the contrary, decalcified thin sections proved to be able to tackle this issue allowing a better reading of the bone tissue. © 2017 Wiley Periodicals, Inc.

  14. Use of Modern Birth Control Methods Among Rural Communities in ...

    African Journals Online (AJOL)

    elearning

    ABSTRACT. This paper studied the extent of utilization of Modern Birth Control Methods (MBCM) among rural dwellers in ... respondents used MBCM while 57% of them used the traditional birth control methods. ..... School of Public Health.

  15. Barriers to utilization of modern methods of family planning amongst ...

    African Journals Online (AJOL)

    Barriers to utilization of modern methods of family planning amongst women in a ... is recognized by the world health organization (WHO) as a universal human right. ... Conclusion: The study finds numerous barriers to utilization of family ...

  16. Chinese Cyber Espionage: A Complementary Method to Aid PLA Modernization

    Science.gov (United States)

    2015-12-01

    COMPLEMENTARY METHOD TO AID PLA MODERNIZATION by Jamie M. Ellis December 2015 Thesis Advisor: Wade L. Huntley Second Reader: Christopher R. Twomey THIS...Master’s Thesis 4. TITLE AND SUBTITLE CHINESE CYBER ESPIONAGE: A COMPLEMENTARY METHOD TO AID PLA MODERNIZATION 5. FUNDING NUMBERS 6. AUTHOR(S) Jamie M...DISTRIBUTION CODE A 13. ABSTRACT (maximum 200 words) In 2013, Mandiant published a report linking one People’s Liberation Army ( PLA ) unit to the

  17. Modern methods in cereal grain mycology

    OpenAIRE

    Olsson, Johan

    2000-01-01

    A simple rapid DNA extraction method, equally suitable for spores and mycelia is proposed. Heating samples in NaOH and SDS provides DNA of high purity, suitable for Polymerase Chain Reaction (PCR) analysis. For Penicillium roqueforti the detection limit was 6 x lo3 conidia and 1 mg (fresh weight) mycelium in the extraction liquid. The method proved efficient with Aspergillus jlavus, Fusarium graminearum, Rhizopus stolonifer, Eurotium herbariorum, and Cladosporium herbarum, as well. An optimis...

  18. Modern methods of wine quality analysis

    Directory of Open Access Journals (Sweden)

    Галина Зуфарівна Гайда

    2015-06-01

    Full Text Available  In this paper physical-chemical and enzymatic methods of quantitative analysis of the basic wine components were reviewed. The results of own experiments were presented for the development of enzyme- and cell-based amperometric sensors on ethanol, lactate, glucose, arginine

  19. Modern recycling methods in metallurgical industry

    Directory of Open Access Journals (Sweden)

    M. Maj

    2010-04-01

    Full Text Available The contamination of environment caused by increased industrial activities is the main topic of discussions in Poland and in the world. The possibilities of waste recovery and recycling vary in different sectors of the industry, and the specific methods, developed and improved all the time, depend on the type of the waste. In this study, the attention has been focussed mainly on the waste from metallurgical industry and on the available techniques of its recycling

  20. Internal scanning method as unique imaging method of optical vortex scanning microscope

    Science.gov (United States)

    Popiołek-Masajada, Agnieszka; Masajada, Jan; Szatkowski, Mateusz

    2018-06-01

    The internal scanning method is specific for the optical vortex microscope. It allows to move the vortex point inside the focused vortex beam with nanometer resolution while the whole beam stays in place. Thus the sample illuminated by the focused vortex beam can be scanned just by the vortex point. We show that this method enables high resolution imaging. The paper presents the preliminary experimental results obtained with the first basic image recovery procedure. A prospect of developing more powerful tools for topography recovery with the optical vortex scanning microscope is discussed shortly.

  1. Knowledge attitude to modern family planning methods in Abraka ...

    African Journals Online (AJOL)

    Objective:. To assess the level of regard and misconceptions of modern family planning methods in Abraka communities. Methods: The interviewer\\'s administered questionnaire method was used to gather the required information from 657 respondents randomly chosen from PO, Ajalomi, Erho, Oria, Otorho, Umeghe, ...

  2. Modern Geometric Methods of Distance Determination

    Science.gov (United States)

    Thévenin, Frédéric; Falanga, Maurizio; Kuo, Cheng Yu; Pietrzyński, Grzegorz; Yamaguchi, Masaki

    2017-11-01

    Building a 3D picture of the Universe at any distance is one of the major challenges in astronomy, from the nearby Solar System to distant Quasars and galaxies. This goal has forced astronomers to develop techniques to estimate or to measure the distance of point sources on the sky. While most distance estimates used since the beginning of the 20th century are based on our understanding of the physics of objects of the Universe: stars, galaxies, QSOs, the direct measures of distances are based on the geometric methods as developed in ancient Greece: the parallax, which has been applied to stars for the first time in the mid-19th century. In this review, different techniques of geometrical astrometry applied to various stellar and cosmological (Megamaser) objects are presented. They consist in parallax measurements from ground based equipment or from space missions, but also in the study of binary stars or, as we shall see, of binary systems in distant extragalactic sources using radio telescopes. The Gaia mission will be presented in the context of stellar physics and galactic structure, because this key space mission in astronomy will bring a breakthrough in our understanding of stars, galaxies and the Universe in their nature and evolution with time. Measuring the distance to a star is the starting point for an unbiased description of its physics and the estimate of its fundamental parameters like its age. Applying these studies to candles such as the Cepheids will impact our large distance studies and calibration of other candles. The text is constructed as follows: introducing the parallax concept and measurement, we shall present briefly the Gaia satellite which will be the future base catalogue of stellar astronomy in the near future. Cepheids will be discussed just after to demonstrate the state of the art in distance measurements in the Universe with these variable stars, with the objective of 1% of error in distances that could be applied to our closest

  3. Fundamentals of modern statistical methods substantially improving power and accuracy

    CERN Document Server

    Wilcox, Rand R

    2001-01-01

    Conventional statistical methods have a very serious flaw They routinely miss differences among groups or associations among variables that are detected by more modern techniques - even under very small departures from normality Hundreds of journal articles have described the reasons standard techniques can be unsatisfactory, but simple, intuitive explanations are generally unavailable Improved methods have been derived, but they are far from obvious or intuitive based on the training most researchers receive Situations arise where even highly nonsignificant results become significant when analyzed with more modern methods Without assuming any prior training in statistics, Part I of this book describes basic statistical principles from a point of view that makes their shortcomings intuitive and easy to understand The emphasis is on verbal and graphical descriptions of concepts Part II describes modern methods that address the problems covered in Part I Using data from actual studies, many examples are include...

  4. Method and computer program product for maintenance and modernization backlogging

    Science.gov (United States)

    Mattimore, Bernard G; Reynolds, Paul E; Farrell, Jill M

    2013-02-19

    According to one embodiment, a computer program product for determining future facility conditions includes a computer readable medium having computer readable program code stored therein. The computer readable program code includes computer readable program code for calculating a time period specific maintenance cost, for calculating a time period specific modernization factor, and for calculating a time period specific backlog factor. Future facility conditions equal the time period specific maintenance cost plus the time period specific modernization factor plus the time period specific backlog factor. In another embodiment, a computer-implemented method for calculating future facility conditions includes calculating a time period specific maintenance cost, calculating a time period specific modernization factor, and calculating a time period specific backlog factor. Future facility conditions equal the time period specific maintenance cost plus the time period specific modernization factor plus the time period specific backlog factor. Other embodiments are also presented.

  5. [Watsu: a modern method in physiotherapy, body regeneration, and sports].

    Science.gov (United States)

    Weber-Nowakowska, Katarzyna; Gebska, Magdalena; Zyzniewska-Banaszak, Ewelina

    2013-01-01

    Progress in existing methods of physiotherapy and body regeneration and introduction of new methods has made it possible to precisely select the techniques according to patient needs. The modern therapist is capable of improving the physical and mental condition of the patient. Watsu helps the therapist eliminate symptoms from the locomotor system and reach the psychic sphere at the same time.

  6. Advanced methods of microscope control using μManager software.

    Science.gov (United States)

    Edelstein, Arthur D; Tsuchida, Mark A; Amodaj, Nenad; Pinkard, Henry; Vale, Ronald D; Stuurman, Nico

    μManager is an open-source, cross-platform desktop application, to control a wide variety of motorized microscopes, scientific cameras, stages, illuminators, and other microscope accessories. Since its inception in 2005, μManager has grown to support a wide range of microscopy hardware and is now used by thousands of researchers around the world. The application provides a mature graphical user interface and offers open programming interfaces to facilitate plugins and scripts. Here, we present a guide to using some of the recently added advanced μManager features, including hardware synchronization, simultaneous use of multiple cameras, projection of patterned light onto a specimen, live slide mapping, imaging with multi-well plates, particle localization and tracking, and high-speed imaging.

  7. Advanced methods of microscope control using μManager software

    Directory of Open Access Journals (Sweden)

    Arthur D Edelstein

    2014-07-01

    Full Text Available µManager is an open-source, cross-platform desktop application, to control a wide variety of motorized microscopes, scientific cameras, stages, illuminators, and other microscope accessories. Since its inception in 2005, µManager has grown to support a wide range of microscopy hardware and is now used by thousands of researchers around the world. The application provides a mature graphical user interface and offers open programming interfaces to facilitate plugins and scripts. Here, we present a guide to using some of the recently added advanced µManager features, including hardware synchronization, simultaneous use of multiple cameras, projection of patterned light onto a specimen, live slide mapping, imaging with multi-well plates, particle localization and tracking, and high-speed imaging.

  8. Hyperspectral microscope imaging methods to classify gram-positive and gram-negative foodborne pathogenic bacteria

    Science.gov (United States)

    An acousto-optic tunable filter-based hyperspectral microscope imaging method has potential for identification of foodborne pathogenic bacteria from microcolony rapidly with a single cell level. We have successfully developed the method to acquire quality hyperspectral microscopic images from variou...

  9. Modern Methods of Voice Authentication in Mobile Devices

    Directory of Open Access Journals (Sweden)

    Vladimir Leonovich Evseev

    2016-03-01

    Full Text Available Modern methods of voice authentication in mobile devices.The proposed evaluation of the probability errors of the first and second kind for multi-modal methods of voice authentication. The advantages of multimodal multivariate methods before, when authentication takes place in several stages – this is the one-stage, which means convenience for customers. Further development of multimodal methods of authentication will be based on the significantly increased computing power of mobile devices, the growing number and improved accuracy built-in mobile device sensors, as well as to improve the algorithms of signal processing.

  10. Membrane Characterization by Microscopic and Scattering Methods: Multiscale Structure

    Directory of Open Access Journals (Sweden)

    Philippe Moulin

    2011-04-01

    Full Text Available Several microscopic and scattering techniques at different observation scales (from atomic to macroscopic were used to characterize both surface and bulk properties of four new flat-sheet polyethersulfone (PES membranes (10, 30, 100 and 300 kDa and new 100 kDa hollow fibers (PVDF. Scanning Electron Microscopy (SEM with “in lens” detection was used to obtain information on the pore sizes of the skin layers at the atomic scale. White Light Interferometry (WLI and Atomic Force Microscopy (AFM using different scales (for WLI: windows: 900 × 900 µm2 and 360 × 360 µm2; number of points: 1024; for AFM: windows: 50 × 50 µm2 and 5 × 5 µm2; number of points: 512 showed that the membrane roughness increases markedly with the observation scale and that there is a continuity between the different scan sizes for the determination of the RMS roughness. High angular resolution ellipsometric measurements were used to obtain the signature of each cut-off and the origin of the scattering was identified as coming from the membrane bulk.

  11. Modern methods to improve the accuracy in fast neutron dosimetry

    International Nuclear Information System (INIS)

    Baers, B.; Karnani, H.; Seren, T.

    1985-01-01

    In order to improve the quality of fast neutron dose estimates at the reactor pressure vessel (PV) some modern methods are presented. In addition to basic principles, some error reduction procedures are also presented based on the combined use of relative measurements, direct sample taking from the pressure vessel and the use of iron and niobium as dosimeters. The influence of large systematic errors could be significantly reduced by carrying out relative measurements. This report also presents the successful use of niobium as a dosimeter by destructive treatment of PV samples. (author)

  12. Modern leadership and management methods for development organizations

    Directory of Open Access Journals (Sweden)

    Samosudova Natalia V.

    2017-01-01

    Full Text Available The following article represents an overview of the basic theoretical concepts of leadership and management in the framework of the organization. The main scientific approaches to leadership are described in conjunction with various leadership styles and their correlation with different levels of effectiveness as a result of the organization’s activity. Certain characteristics applicable to leaders and managers are mentioned. Attitude and obligations of a modern construction project manager are discussed, along with the challenges the construction industry represents these days. Ideas about methods of complex analysis for further research and identifying leadership tactics and their impact on the success of the development organization are suggested.

  13. Modern Methods for Cost Management in Construction Enterprises

    Directory of Open Access Journals (Sweden)

    Mesároš Peter

    2015-06-01

    Full Text Available Cost management should be seen as an essential function of enterprises which perform their activities in current market environment. One of the main factors affecting the level of achieved profit and favourable market position is cost structure. The company's ability to obtain necessary and reliable information on their own cost, subsequent processing and effective cost management is crucial for achieving success. This study focuses on cost management and the use of modern methods of cost management in construction enterprises. The aim of this paper is to identify approaches to cost management in Slovak construction enterprises, based on own empirical research.

  14. Modern acupuncture-like stimulation methods: a literature review

    Directory of Open Access Journals (Sweden)

    Min-Ho Jun

    2015-12-01

    Full Text Available Acupuncture therapy has been proved to be effective for diverse diseases, symptoms, and conditions in numerous clinical trials. The growing popularity of acupuncture therapy has triggered the development of modern acupuncture-like stimulation devices (ASDs, which are equivalent or superior to manual acupuncture with respect to safety, decreased risk of infection, and facilitation of clinical trials. Here, we aim to summarize the research on modern ASDs, with a focus on featured devices undergoing active research and their effectiveness and target symptoms, along with annual publication rates. We searched the popular electronic databases Medline, PubMed, the Cochrane Library, and Web of Science, and analyzed English-language studies on humans. Thereby, a total of 728 studies were identified, of which 195 studies met our inclusion criteria. Electrical stimulators were found to be the earliest and most widely studied devices (133 articles, followed by laser (44 articles, magnetic (16 articles, and ultrasound (2 articles stimulators. A total of 114 studies used randomized controlled trials, and 109 studies reported therapeutic benefits. The majority of the studies (32% focused on analgesia and pain-relief effects, followed by effects on brain activity (16%. All types of the reviewed ASDs were associated with increasing annual publication trends; specifically, the annual growth in publications regarding noninvasive stimulation methods was more rapid than that regarding invasive methods. Based on this observation, we anticipate that the noninvasive or minimally invasive ASDs will become more popular in acupuncture therapy.

  15. Rapid identification of salmonella serotypes with stereo and hyperspectral microscope imaging Methods

    Science.gov (United States)

    The hyperspectral microscope imaging (HMI) method can reduce detection time within 8 hours including incubation process. The early and rapid detection with this method in conjunction with the high throughput capabilities makes HMI method a prime candidate for implementation for the food industry. Th...

  16. Coarse Analysis of Microscopic Models using Equation-Free Methods

    DEFF Research Database (Denmark)

    Marschler, Christian

    of these models might be high-dimensional, the properties of interest are usually macroscopic and lowdimensional in nature. Examples are numerous and not necessarily restricted to computer models. For instance, the power output, energy consumption and temperature of engines are interesting quantities....... Applications include the learning behavior in the barn owl’s auditory system, traffic jam formation in an optimal velocity model for circular car traffic and oscillating behavior of pedestrian groups in a counter-flow through a corridor with narrow door. The methods do not only quantify interesting properties...... in these models (learning outcome, traffic jam density, oscillation period), but also allow to investigate unstable solutions, which are important information to determine basins of attraction of stable solutions and thereby reveal information on the long-term behavior of an initial state....

  17. Modern methods of studying surfaces and their application to glasses

    International Nuclear Information System (INIS)

    Rauschenbach, B.; Haehnert, M.

    1977-05-01

    In the works are demonstrated modern methods for study of solid surfaces and its use of glasses. Study of the interaction of ions, electrons and photons with the glass surface provides information about the composition of the surface and its structure on an atomic scale. A qualitative analysis of a surface can be made with the aid of the Auger electron spectroscopy (AES) and the electron spectroscopy for chemical analysis (ESCA) and with the ion scattering (ISS and RBS) and the secondary ion mass spectrometry (SIMS). The structure of a surface can be studied by means of ion scattering and low-energy electron diffraction (LEED) and the topography of a surface by means of scanning electron microscopy (SEM). The ellipsometry is generally confined to measuring the thickness of very thin layers. The application these methods to the glass surfaces is demonstrated on series of examples. (author)

  18. Fibonacci’s Computation Methods vs Modern Algorithms

    Directory of Open Access Journals (Sweden)

    Ernesto Burattini

    2013-12-01

    Full Text Available In this paper we discuss some computational procedures given by Leonardo Pisano Fibonacci in his famous Liber Abaci book, and we propose their translation into a modern language for computers (C ++. Among the other we describe the method of “cross” multiplication, we evaluate its computational complexity in algorithmic terms and we show the output of a C ++ code that describes the development of the method applied to the product of two integers. In a similar way we show the operations performed on fractions introduced by Fibonacci. Thanks to the possibility to reproduce on a computer, the Fibonacci’s different computational procedures, it was possible to identify some calculation errors present in the different versions of the original text.

  19. INNOVATIVE METHODS OF TEACHING HISTORY AT MODERN UNIVERSITIES

    Directory of Open Access Journals (Sweden)

    A. Yu. Suslov

    2017-01-01

    Full Text Available Introduction. As a discipline, History holds a specific place among disciplines of a humanitarian cycle of educational programs of higher education institutions regardless of university specialities. History plays an important role in the course of formation of a citizen and development of critical thinking of a personality as an element of a common culture. However, new federal standards require a drastic reduction of the classroom hours for studying a History course by students of non-humanitarian specialties, and, at the same time, enhancement of the contents of a discipline (its reorientation from History of Russia towards World History. Therefore, History programmes and courses demand up-to-date approaches, methods and didactic means to provide formation of holistic worldview of future experts.The aim of the article is to consider the features of innovative methods application in teaching history in high school taking into consideration modernization processes.Methodology and research methods. The research undertaken is based on activity and competence-based approaches. The methods of analysis and synthesis of the academic literature on the research topic were used; the methods of reflection and generalization of teaching activities of the Department of Humanitarian Disciplines of theKazanNationalResearchTechnologicalUniversity were applied as well.Results and scientific novelty. A modern view on historical education has been proposed as means of students’ systems thinking formation, designing the ideas about the world historical process among students, the mission ofRussia in this process, and evolution ofRussia as a part of the modern civilization. It is stated that History university course is designed not only to give the students strong subject knowledge, but also to create axiological orientations and abilities on the basis of the analysis of historical collisions, objective and subjective factors of society development. Moreover

  20. Acousto-Optic Tunable Filter Hyperspectral Microscope Imaging Method for Characterizing Spectra from Foodborne Pathogens.

    Science.gov (United States)

    Hyperspectral microscope imaging (HMI) method, which provides both spatial and spectral characteristics of samples, can be effective for foodborne pathogen detection. The acousto-optic tunable filter (AOTF)-based HMI method can be used to characterize spectral properties of biofilms formed by Salmon...

  1. Modern methodic of power cardio training in students’ physical education

    Directory of Open Access Journals (Sweden)

    A.Yu. Osipov

    2016-12-01

    Full Text Available Purpose: significant increase of students’ physical condition and health level at the account of application of modern power cardio training methodic. Material: 120 students (60 boys and 60 girls participated in the research. The age of the tested was 19 years. The research took one year. We used methodic of power and functional impact on trainees’ organism (HOT IRON. Such methodic is some systems of physical exercises with weights (mini-barbells, to be fulfilled under accompaniment of specially selected music. Results: we showed advantages of power-cardio and fitness trainings in students’ health improvement and in elimination obesity. Control tests showed experimental group students achieved confidently higher physical indicators. Boys demonstrated increase of physical strength and general endurance indicators. Girls had confidently better indicators of physical strength, flexibility and general endurance. Increase of control group students’ body mass can be explained by students’ insufficient physical activity at trainings, conducted as per traditional program. Conclusions: students’ trainings by power-cardio methodic with application HOT IRON exercises facilitate development the following physical qualities: strength and endurance in boys and strength, flexibility and endurance in girls. Besides, it was found that such systems of exercises facilitate normalization of boys’ body mass and correction of girls’ constitution.

  2. Pair Programming as a Modern Method of Teaching Computer Science

    Directory of Open Access Journals (Sweden)

    Irena Nančovska Šerbec

    2008-10-01

    Full Text Available At the Faculty of Education, University of Ljubljana we educate future computer science teachers. Beside didactical, pedagogical, mathematical and other interdisciplinary knowledge, students gain knowledge and skills of programming that are crucial for computer science teachers. For all courses, the main emphasis is the absorption of professional competences, related to the teaching profession and the programming profile. The latter are selected according to the well-known document, the ACM Computing Curricula. The professional knowledge is therefore associated and combined with the teaching knowledge and skills. In the paper we present how to achieve competences related to programming by using different didactical models (semiotic ladder, cognitive objectives taxonomy, problem solving and modern teaching method “pair programming”. Pair programming differs from standard methods (individual work, seminars, projects etc.. It belongs to the extreme programming as a discipline of software development and is known to have positive effects on teaching first programming language. We have experimentally observed pair programming in the introductory programming course. The paper presents and analyzes the results of using this method: the aspects of satisfaction during programming and the level of gained knowledge. The results are in general positive and demonstrate the promising usage of this teaching method.

  3. Mechanical vibration compensation method for 3D+t multi-particle tracking in microscopic volumes.

    Science.gov (United States)

    Pimentel, A; Corkidi, G

    2009-01-01

    The acquisition and analysis of data in microscopic systems with spatiotemporal evolution is a very relevant topic. In this work, we describe a method to optimize an experimental setup for acquiring and processing spatiotemporal (3D+t) data in microscopic systems. The method is applied to a three-dimensional multi-tracking and analysis system of free-swimming sperm trajectories previously developed. The experimental set uses a piezoelectric device making oscillate a large focal-distance objective mounted on an inverted microscope (over its optical axis) to acquire stacks of images at a high frame rate over a depth on the order of 250 microns. A problem arise when the piezoelectric device oscillates, in such a way that a vibration is transmitted to the whole microscope, inducing undesirable 3D vibrations to the whole set. For this reason, as a first step, the biological preparation was isolated from the body of the microscope to avoid modifying the free swimming pattern of the microorganism due to the transmission of these vibrations. Nevertheless, as the image capturing device is mechanically attached to the "vibrating" microscope, the resulting acquired data are contaminated with an undesirable 3D movement that biases the original trajectory of these high speed moving cells. The proposed optimization method determines the functional form of these 3D oscillations to neutralize them from the original acquired data set. Given the spatial scale of the system, the added correction increases significantly the data accuracy. The optimized system may be very useful in a wide variety of 3D+t applications using moving optical devices.

  4. Automatic segmentation of Leishmania parasite in microscopic images using a modified CV level set method

    Science.gov (United States)

    Farahi, Maria; Rabbani, Hossein; Talebi, Ardeshir; Sarrafzadeh, Omid; Ensafi, Shahab

    2015-12-01

    Visceral Leishmaniasis is a parasitic disease that affects liver, spleen and bone marrow. According to World Health Organization report, definitive diagnosis is possible just by direct observation of the Leishman body in the microscopic image taken from bone marrow samples. We utilize morphological and CV level set method to segment Leishman bodies in digital color microscopic images captured from bone marrow samples. Linear contrast stretching method is used for image enhancement and morphological method is applied to determine the parasite regions and wipe up unwanted objects. Modified global and local CV level set methods are proposed for segmentation and a shape based stopping factor is used to hasten the algorithm. Manual segmentation is considered as ground truth to evaluate the proposed method. This method is tested on 28 samples and achieved 10.90% mean of segmentation error for global model and 9.76% for local model.

  5. New method for thickness determination and microscopic imaging of graphene-like two-dimensional materials

    International Nuclear Information System (INIS)

    Qin Xudong; Chen Yonghai; Liu Yu; Zhu Laipan; Li Yuan; Wu Qing; Huang Wei

    2016-01-01

    We employed the microscopic reflectance difference spectroscopy (micro-RDS) to determine the layer-number and microscopically image the surface topography of graphene and MoS 2 samples. The contrast image shows the efficiency and reliability of this new clipping technique. As a low-cost, quantifiable, no-contact and non-destructive method, it is not concerned with the characteristic signal of certain materials and can be applied to arbitrary substrates. Therefore it is a perfect candidate for characterizing the thickness of graphene-like two-dimensional materials. (paper)

  6. Extended morphological processing: a practical method for automatic spot detection of biological markers from microscopic images.

    Science.gov (United States)

    Kimori, Yoshitaka; Baba, Norio; Morone, Nobuhiro

    2010-07-08

    A reliable extraction technique for resolving multiple spots in light or electron microscopic images is essential in investigations of the spatial distribution and dynamics of specific proteins inside cells and tissues. Currently, automatic spot extraction and characterization in complex microscopic images poses many challenges to conventional image processing methods. A new method to extract closely located, small target spots from biological images is proposed. This method starts with a simple but practical operation based on the extended morphological top-hat transformation to subtract an uneven background. The core of our novel approach is the following: first, the original image is rotated in an arbitrary direction and each rotated image is opened with a single straight line-segment structuring element. Second, the opened images are unified and then subtracted from the original image. To evaluate these procedures, model images of simulated spots with closely located targets were created and the efficacy of our method was compared to that of conventional morphological filtering methods. The results showed the better performance of our method. The spots of real microscope images can be quantified to confirm that the method is applicable in a given practice. Our method achieved effective spot extraction under various image conditions, including aggregated target spots, poor signal-to-noise ratio, and large variations in the background intensity. Furthermore, it has no restrictions with respect to the shape of the extracted spots. The features of our method allow its broad application in biological and biomedical image information analysis.

  7. Specimen holder for an electron microscope and device and method for mounting a specimen in an electron microscope

    NARCIS (Netherlands)

    Zandbergen, H.W.; Latenstein van Voorst, A.; Westra, C.; Hoveling, G.H.

    1996-01-01

    A specimen holder for an electron microscope, comprising a bar-shaped body provided adjacent one end with means for receiving a specimen, with means being present for screening the specimen from the environment at least temporarily in airtight and moisture-proof manner in a first position, which

  8. Chinese cyber espionage: a complementary method to aid PLA modernization

    OpenAIRE

    Ellis, Jamie M.

    2015-01-01

    Approved for public release; distribution is unlimited In 2013, Mandiant published a report linking one People’s Liberation Army (PLA) unit to the virtual exploitation of 11 modern U.S. military platforms. In the last two decades, Chinese cyber espionage has cultivated a significant reputation in cyberspace for its high-volume, illicit exploitation of defense technology. At the same time, the PLA has also rapidly modernized its naval, fighter jet, and air defense technologies. This thesis ...

  9. Elementary and advanced Lie algebraic methods with applications to accelerator design, electron microscopes, and light optics

    International Nuclear Information System (INIS)

    Dragt, A.J.

    1987-01-01

    A review is given of elementary Lie algebraic methods for treating Hamiltonian systems. This review is followed by a brief exposition of advanced Lie algebraic methods including resonance bases and conjugacy theorems. Finally, applications are made to the design of third-order achromats for use in accelerators, to the design of subangstroem resolution electron microscopes, and to the classification and study of high order aberrations in light optics. (orig.)

  10. Dense and refined microstructure 3D measurement method based on an optical microscope and varying illuminations

    International Nuclear Information System (INIS)

    Li, Zhongwei; Li, Y F

    2011-01-01

    We propose a novel microscopic photometric stereo (MPS) method based on a conventional optical microscope and varying illuminations for dense and refined microstructure 3D measurement. To guarantee the flexibility of the MPS, an uncalibrated photometric stereo (UPS) method, which does not require a priori knowledge of the light-source direction or the light-source intensity, is employed to recover surface normals and albedos from the captured multiple micro-images. Although the UPS has been studied before, there are some particular issues to be addressed to make it suitable for microscopic cases. For resolving the inherent generalized bas-relief (GBR) ambiguity of the UPS, we present a GBR disambiguation method based on a framework of entropy minimization, and extend it using a graph-cut energy minimization to decrease the influence of noise and further refine the recovered surface normal. The proposed MPS method has been tested on synthetic as well as real images and very encouraging results have been obtained. The experimental results show that this novel method can reconstruct dense and refined 3D points for the microstructure. It is an easy-to-implement yet effective alternative method for microstructure 3D measurement and can be applied to many potential fields

  11. Spine surgeon's kinematics during discectomy, part II: operating table height and visualization methods, including microscope.

    Science.gov (United States)

    Park, Jeong Yoon; Kim, Kyung Hyun; Kuh, Sung Uk; Chin, Dong Kyu; Kim, Keun Su; Cho, Yong Eun

    2014-05-01

    Surgeon spine angle during surgery was studied ergonomically and the kinematics of the surgeon's spine was related with musculoskeletal fatigue and pain. Spine angles varied depending on operation table height and visualization method, and in a previous paper we showed that the use of a loupe and a table height at the midpoint between the umbilicus and the sternum are optimal for reducing musculoskeletal loading. However, no studies have previously included a microscope as a possible visualization method. The objective of this study is to assess differences in surgeon spine angles depending on operating table height and visualization method, including microscope. We enrolled 18 experienced spine surgeons for this study, who each performed a discectomy using a spine surgery simulator. Three different methods were used to visualize the surgical field (naked eye, loupe, microscope) and three different operating table heights (anterior superior iliac spine, umbilicus, the midpoint between the umbilicus and the sternum) were studied. Whole spine angles were compared for three different views during the discectomy simulation: midline, ipsilateral, and contralateral. A 16-camera optoelectronic motion analysis system was used, and 16 markers were placed from the head to the pelvis. Lumbar lordosis, thoracic kyphosis, cervical lordosis, and occipital angle were compared between the different operating table heights and visualization methods as well as a natural standing position. Whole spine angles differed significantly depending on visualization method. All parameters were closer to natural standing values when discectomy was performed with a microscope, and there were no differences between the naked eye and the loupe. Whole spine angles were also found to differ from the natural standing position depending on operating table height, and became closer to natural standing position values as the operating table height increased, independent of the visualization method

  12. Non-contact micro mass evaluation method using an X-ray microscope

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jiseok; Sun, Gwang Min; Baek, Ha Ni; Hoang, Sy Minh Tuan; Park, Sun Ae [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2017-07-15

    For the mass inspection of attached foils such as printed electrodes, mass should be measured by a non-contact method with the capacity to measure a small mass of micrograms. In this study, the masses of 1 mg to 10 mg electrodes were evaluated using an X-ray microscope. The results were compared with the masses determined by using a digital scale with a 0.005 mg error. The average of the relative error between the mass measurements using the X-ray microscope and those using the digital scale was less than 2.51%. The results show that X-ray mass evaluation method can be used for mass measurement of micro objects by replacing a digital scale.

  13. The plant virus microscope image registration method based on mismatches removing.

    Science.gov (United States)

    Wei, Lifang; Zhou, Shucheng; Dong, Heng; Mao, Qianzhuo; Lin, Jiaxiang; Chen, Riqing

    2016-01-01

    The electron microscopy is one of the major means to observe the virus. The view of virus microscope images is limited by making specimen and the size of the camera's view field. To solve this problem, the virus sample is produced into multi-slice for information fusion and image registration techniques are applied to obtain large field and whole sections. Image registration techniques have been developed in the past decades for increasing the camera's field of view. Nevertheless, these approaches typically work in batch mode and rely on motorized microscopes. Alternatively, the methods are conceived just to provide visually pleasant registration for high overlap ratio image sequence. This work presents a method for virus microscope image registration acquired with detailed visual information and subpixel accuracy, even when overlap ratio of image sequence is 10% or less. The method proposed focus on the correspondence set and interimage transformation. A mismatch removal strategy is proposed by the spatial consistency and the components of keypoint to enrich the correspondence set. And the translation model parameter as well as tonal inhomogeneities is corrected by the hierarchical estimation and model select. In the experiments performed, we tested different registration approaches and virus images, confirming that the translation model is not always stationary, despite the fact that the images of the sample come from the same sequence. The mismatch removal strategy makes building registration of virus microscope images at subpixel accuracy easier and optional parameters for building registration according to the hierarchical estimation and model select strategies make the proposed method high precision and reliable for low overlap ratio image sequence. Copyright © 2015 Elsevier Ltd. All rights reserved.

  14. Contribution to the projected Hartree-Fock method and microscopic theory of coupling between rotation bands

    International Nuclear Information System (INIS)

    Brut, F.

    1982-01-01

    The spectroscopy of odd-A nuclei, in the 1p and 2s-1d shells, is studied in the framework of the projected Hartree-Fock method and by the generator coordinate method. The nuclear effective interactions of Cohen and Kurath, on the one hand, and of Kuo or Preedom-Wildenthal, on the other hand, are used. The binding energies, the nuclear spectra, the static moments and the electromagnetic transitions obtained by these two approaches are compared to the same quantities given by a complete diagonalization in the shell model basis. This study of light nuclei gives some possibilities to put in order the energy levels by coupled rotational bands. In the microscopic approach, thus we find all the elements of the unified model of Bohr and Mottelson. To give evidence of such a relation, the functions of the angle β, in the integrals of the projection method of Peierls and Yoccoz, for a Slater determinant, are developed in the vicinity of the bounds β = O and β = π. The microscopic coefficients are evaluated in the Hartree-Fock approximation, using the particle-hole formalism. Calculations are made for 20 Ne and 21 Ne and the resulting microscopic coefficients are compared with the corresponding terms of the unified model of Bohr and Mottelson [fr

  15. Comparison between laser terahertz emission microscope and conventional methods for analysis of polycrystalline silicon solar cell

    Directory of Open Access Journals (Sweden)

    Hidetoshi Nakanishi

    2015-11-01

    Full Text Available A laser terahertz emission microscope (LTEM can be used for noncontact inspection to detect the waveforms of photoinduced terahertz emissions from material devices. In this study, we experimentally compared the performance of LTEM with conventional analysis methods, e.g., electroluminescence (EL, photoluminescence (PL, and laser beam induced current (LBIC, as an inspection method for solar cells. The results showed that LTEM was more sensitive to the characteristics of the depletion layer of the polycrystalline solar cell compared with EL, PL, and LBIC and that it could be used as a complementary tool to the conventional analysis methods for a solar cell.

  16. Utilisation des methodes modernes et reversibles de contraception ...

    African Journals Online (AJOL)

    Cette étude descriptive et transversale de 6 ans, allant du 1er Janvier 1999 au 10 Mai 2005 à la clinique de gynécologie obstétrique de l\\'hôpital Donka du CHU de Conakry, a fait ressortir le niveau d\\'utilisation des méthodes modernes de contraception et a permis d\\'élaboré des recommandations pour l\\'amélioration de la ...

  17. A scanning tunneling microscope break junction method with continuous bias modulation.

    Science.gov (United States)

    Beall, Edward; Yin, Xing; Waldeck, David H; Wierzbinski, Emil

    2015-09-28

    Single molecule conductance measurements on 1,8-octanedithiol were performed using the scanning tunneling microscope break junction method with an externally controlled modulation of the bias voltage. Application of an AC voltage is shown to improve the signal to noise ratio of low current (low conductance) measurements as compared to the DC bias method. The experimental results show that the current response of the molecule(s) trapped in the junction and the solvent media to the bias modulation can be qualitatively different. A model RC circuit which accommodates both the molecule and the solvent is proposed to analyze the data and extract a conductance for the molecule.

  18. A new method to detect geometrical information by the tunneling microscope

    DEFF Research Database (Denmark)

    Tasaki, S.; Levitan, J.; Mygind, Jesper

    1997-01-01

    A new method for the detection of the geometrical information by the scanning tunneling microscope is proposed. In addition to the bias voltage, a small ac modulation is applied. The nonlinear dependence of the transmission coefficient on the applied voltage is used to generate harmonics. The ratio...... of the harmonics to the dc current is found to give the width between the sample and the probe, i.e., the geometrical information. This method may be useful to measure materials, where the local-spatial-density of states may change notably from place to place. ©1997 American Institute of Physics....

  19. Convergence of methods for coupling of microscopic and mesoscopic reaction–diffusion simulations

    KAUST Repository

    Flegg, Mark B.; Hellander, Stefan; Erban, Radek

    2015-01-01

    © 2015 Elsevier Inc. In this paper, three multiscale methods for coupling of mesoscopic (compartment-based) and microscopic (molecular-based) stochastic reaction-diffusion simulations are investigated. Two of the three methods that will be discussed in detail have been previously reported in the literature; the two-regime method (TRM) and the compartment-placement method (CPM). The third method that is introduced and analysed in this paper is called the ghost cell method (GCM), since it works by constructing a "ghost cell" in which molecules can disappear and jump into the compartment-based simulation. Presented is a comparison of sources of error. The convergent properties of this error are studied as the time step δ. t (for updating the molecular-based part of the model) approaches zero. It is found that the error behaviour depends on another fundamental computational parameter h, the compartment size in the mesoscopic part of the model. Two important limiting cases, which appear in applications, are considered:. (i)δt→0 and h is fixed;(ii)δt→0 and h→0 such that δt/h is fixed. The error for previously developed approaches (the TRM and CPM) converges to zero only in the limiting case (ii), but not in case (i). It is shown that the error of the GCM converges in the limiting case (i). Thus the GCM is superior to previous coupling techniques if the mesoscopic description is much coarser than the microscopic part of the model.

  20. Convergence of methods for coupling of microscopic and mesoscopic reaction–diffusion simulations

    KAUST Repository

    Flegg, Mark B.

    2015-05-01

    © 2015 Elsevier Inc. In this paper, three multiscale methods for coupling of mesoscopic (compartment-based) and microscopic (molecular-based) stochastic reaction-diffusion simulations are investigated. Two of the three methods that will be discussed in detail have been previously reported in the literature; the two-regime method (TRM) and the compartment-placement method (CPM). The third method that is introduced and analysed in this paper is called the ghost cell method (GCM), since it works by constructing a "ghost cell" in which molecules can disappear and jump into the compartment-based simulation. Presented is a comparison of sources of error. The convergent properties of this error are studied as the time step δ. t (for updating the molecular-based part of the model) approaches zero. It is found that the error behaviour depends on another fundamental computational parameter h, the compartment size in the mesoscopic part of the model. Two important limiting cases, which appear in applications, are considered:. (i)δt→0 and h is fixed;(ii)δt→0 and h→0 such that δt/h is fixed. The error for previously developed approaches (the TRM and CPM) converges to zero only in the limiting case (ii), but not in case (i). It is shown that the error of the GCM converges in the limiting case (i). Thus the GCM is superior to previous coupling techniques if the mesoscopic description is much coarser than the microscopic part of the model.

  1. A landmark-based method for the geometrical 3D calibration of scanning microscopes

    Energy Technology Data Exchange (ETDEWEB)

    Ritter, M.

    2007-04-27

    This thesis presents a new strategy and a spatial method for the geometric calibration of 3D measurement devices at the micro-range, based on spatial reference structures with nanometersized landmarks (nanomarkers). The new method was successfully applied for the 3D calibration of scanning probe microscopes (SPM) and confocal laser scanning microscopes (CLSM). Moreover, the spatial method was also used for the photogrammetric self-calibration of scanning electron microscopes (SEM). In order to implement the calibration strategy to all scanning microscopes used, the landmark-based principle of reference points often applied at land survey or at close-range applications has been transferred to the nano- and micro-range in the form of nanomarker. In order to function as a support to the nanomarkers, slope-shaped step pyramids have been developed and fabricated by focused ion beam (FIB) induced metal deposition. These FIB produced 3D microstructures have been sized to embrace most of the measurement volume of the scanning microscopes. Additionally, their special design allows the homogenous distribution of the nanomarkers. The nanomarkers were applied onto the support and the plateaus of the slope-step pyramids by FIB etching (milling) as landmarks with as little as several hundreds of nanometers in diameter. The nanomarkers are either of point-, or ring-shaped design. They are optimized so that they can be spatially measured by SPM and CLSM, and, imaged and photogrammetrically analyzed on the basis of SEM data. The centre of the each nanomarker serves as reference point in the measurement data or images. By applying image processing routines, the image (2D) or object (3D) coordinates of each nanomarker has been determined with subpixel accuracy. The correlative analysis of the SPM, CLSM and photogrammetric SEM measurement data after 3D calibration resulted in mean residues in the measured coordinates of as little as 13 nm. Without the coupling factors the mean

  2. Microscope image based fully automated stomata detection and pore measurement method for grapevines

    Directory of Open Access Journals (Sweden)

    Hiranya Jayakody

    2017-11-01

    Full Text Available Abstract Background Stomatal behavior in grapevines has been identified as a good indicator of the water stress level and overall health of the plant. Microscope images are often used to analyze stomatal behavior in plants. However, most of the current approaches involve manual measurement of stomatal features. The main aim of this research is to develop a fully automated stomata detection and pore measurement method for grapevines, taking microscope images as the input. The proposed approach, which employs machine learning and image processing techniques, can outperform available manual and semi-automatic methods used to identify and estimate stomatal morphological features. Results First, a cascade object detection learning algorithm is developed to correctly identify multiple stomata in a large microscopic image. Once the regions of interest which contain stomata are identified and extracted, a combination of image processing techniques are applied to estimate the pore dimensions of the stomata. The stomata detection approach was compared with an existing fully automated template matching technique and a semi-automatic maximum stable extremal regions approach, with the proposed method clearly surpassing the performance of the existing techniques with a precision of 91.68% and an F1-score of 0.85. Next, the morphological features of the detected stomata were measured. Contrary to existing approaches, the proposed image segmentation and skeletonization method allows us to estimate the pore dimensions even in cases where the stomatal pore boundary is only partially visible in the microscope image. A test conducted using 1267 images of stomata showed that the segmentation and skeletonization approach was able to correctly identify the stoma opening 86.27% of the time. Further comparisons made with manually traced stoma openings indicated that the proposed method is able to estimate stomata morphological features with accuracies of 89.03% for area

  3. 9Be scattering with microscopic wave functions and the continuum-discretized coupled-channel method

    Science.gov (United States)

    Descouvemont, P.; Itagaki, N.

    2018-01-01

    We use microscopic 9Be wave functions defined in a α +α +n multicluster model to compute 9Be+target scattering cross sections. The parameter sets describing 9Be are generated in the spirit of the stochastic variational method, and the optimal solution is obtained by superposing Slater determinants and by diagonalizing the Hamiltonian. The 9Be three-body continuum is approximated by square-integral wave functions. The 9Be microscopic wave functions are then used in a continuum-discretized coupled-channel (CDCC) calculation of 9Be+208Pb and of 9Be+27Al elastic scattering. Without any parameter fitting, we obtain a fair agreement with experiment. For a heavy target, the influence of 9Be breakup is important, while it is weaker for light targets. This result confirms previous nonmicroscopic CDCC calculations. One of the main advantages of the microscopic CDCC is that it is based on nucleon-target interactions only; there is no adjustable parameter. The present work represents a first step towards more ambitious calculations involving heavier Be isotopes.

  4. New deconvolution method for microscopic images based on the continuous Gaussian radial basis function interpolation model.

    Science.gov (United States)

    Chen, Zhaoxue; Chen, Hao

    2014-01-01

    A deconvolution method based on the Gaussian radial basis function (GRBF) interpolation is proposed. Both the original image and Gaussian point spread function are expressed as the same continuous GRBF model, thus image degradation is simplified as convolution of two continuous Gaussian functions, and image deconvolution is converted to calculate the weighted coefficients of two-dimensional control points. Compared with Wiener filter and Lucy-Richardson algorithm, the GRBF method has an obvious advantage in the quality of restored images. In order to overcome such a defect of long-time computing, the method of graphic processing unit multithreading or increasing space interval of control points is adopted, respectively, to speed up the implementation of GRBF method. The experiments show that based on the continuous GRBF model, the image deconvolution can be efficiently implemented by the method, which also has a considerable reference value for the study of three-dimensional microscopic image deconvolution.

  5. A method to determine the number of nanoparticles in a cluster using conventional optical microscopes

    International Nuclear Information System (INIS)

    Kang, Hyeonggon; Attota, Ravikiran; Tondare, Vipin; Vladár, András E.; Kavuri, Premsagar

    2015-01-01

    We present a method that uses conventional optical microscopes to determine the number of nanoparticles in a cluster, which is typically not possible using traditional image-based optical methods due to the diffraction limit. The method, called through-focus scanning optical microscopy (TSOM), uses a series of optical images taken at varying focus levels to achieve this. The optical images cannot directly resolve the individual nanoparticles, but contain information related to the number of particles. The TSOM method makes use of this information to determine the number of nanoparticles in a cluster. Initial good agreement between the simulations and the measurements is also presented. The TSOM method can be applied to fluorescent and non-fluorescent as well as metallic and non-metallic nano-scale materials, including soft materials, making it attractive for tag-less, high-speed, optical analysis of nanoparticles down to 45 nm diameter

  6. Cancer cell imaging by stable wet near-field scanning optical microscope with resonance tracking method

    International Nuclear Information System (INIS)

    Park, Kyoung-Duck; Park, Doo-Jae; Jeong, Mun-Seok; Choi, Geun-Chang; Lee, Seung-Gol; Byeon, Clare-Chisu; Choi, Soo-Bong

    2014-01-01

    We report on a successful topographical and optical imaging of various cancer cells in liquid and in air by using a stable wet near-field scanning optical microscope that utilizes a resonance tracking method. We observed a clear dehydration which gives rise to a decrease in the cell volume down to 51%. In addition, a micro-ball lens effect due to the round-shaped young cancer cells was observed from near-field imaging, where the refractive index of young cancer cells was deduced.

  7. Cancer cell imaging by stable wet near-field scanning optical microscope with resonance tracking method

    Energy Technology Data Exchange (ETDEWEB)

    Park, Kyoung-Duck [Sungkyunkwan University, Suwon (Korea, Republic of); Inha University, Incheon (Korea, Republic of); Park, Doo-Jae; Jeong, Mun-Seok [Sungkyunkwan University, Suwon (Korea, Republic of); Choi, Geun-Chang [Seoul National University, Seoul (Korea, Republic of); Lee, Seung-Gol [Inha University, Incheon (Korea, Republic of); Byeon, Clare-Chisu [Kyungpook National University, Daegu (Korea, Republic of); Choi, Soo-Bong [Incheon National University, Incheon (Korea, Republic of)

    2014-05-15

    We report on a successful topographical and optical imaging of various cancer cells in liquid and in air by using a stable wet near-field scanning optical microscope that utilizes a resonance tracking method. We observed a clear dehydration which gives rise to a decrease in the cell volume down to 51%. In addition, a micro-ball lens effect due to the round-shaped young cancer cells was observed from near-field imaging, where the refractive index of young cancer cells was deduced.

  8. Transmission electron microscopic method for gene mapping on polytene chromosomes by in situ hybridization

    OpenAIRE

    Wu, Madeline; Davidson, Norman

    1981-01-01

    A transmission electron microscope method for gene mapping by in situ hybridization to Drosophila polytene chromosomes has been developed. As electron-opaque labels, we use colloidal gold spheres having a diameter of 25 nm. The spheres are coated with a layer of protein to which Escherichia coli single-stranded DNA is photochemically crosslinked. Poly(dT) tails are added to the 3' OH ends of these DNA strands, and poly(dA) tails are added to the 3' OH ends of a fragmented cloned Drosophila DN...

  9. Problematic Methods in teaching Modern History. An alternative or a necessity?

    Directory of Open Access Journals (Sweden)

    Yohany Peralta Pérez

    2012-06-01

    Full Text Available The article presents the results of the analysis from the study of the theoretical research on the use of problematic methods in Teaching Learning Process of Modern H istory course in Rafael Maria de Mendive University of Pinar del Rio. An anal ysis o f the use of problematic methods in the Process of Teaching Modern History course from the definition of method taking into account the theoretical assumptions of scholars of the subject matter and the advantages and disadvantages provided by the use of these methods in the Teaching Learning Process of Modern History course.

  10. Adaptive and automatic red blood cell counting method based on microscopic hyperspectral imaging technology

    Science.gov (United States)

    Liu, Xi; Zhou, Mei; Qiu, Song; Sun, Li; Liu, Hongying; Li, Qingli; Wang, Yiting

    2017-12-01

    Red blood cell counting, as a routine examination, plays an important role in medical diagnoses. Although automated hematology analyzers are widely used, manual microscopic examination by a hematologist or pathologist is still unavoidable, which is time-consuming and error-prone. This paper proposes a full-automatic red blood cell counting method which is based on microscopic hyperspectral imaging of blood smears and combines spatial and spectral information to achieve high precision. The acquired hyperspectral image data of the blood smear in the visible and near-infrared spectral range are firstly preprocessed, and then a quadratic blind linear unmixing algorithm is used to get endmember abundance images. Based on mathematical morphological operation and an adaptive Otsu’s method, a binaryzation process is performed on the abundance images. Finally, the connected component labeling algorithm with magnification-based parameter setting is applied to automatically select the binary images of red blood cell cytoplasm. Experimental results show that the proposed method can perform well and has potential for clinical applications.

  11. Comparison of microscopic method and computational program for pesticide deposition evaluation of spraying

    Directory of Open Access Journals (Sweden)

    Chaim Aldemir

    2002-01-01

    Full Text Available The main objective of this work was to compare two methods to estimate the deposition of pesticide applied by aerial spraying. Hundred and fifty pieces of water sensitive paper were distributed over an area of 50 m length by 75 m width for sampling droplets sprayed by an aircraft calibrated to apply a spray volume of 32 L/ha. The samples were analysed by visual microscopic method using NG 2 Porton graticule and by an image analyser computer program. The results reached by visual microscopic method were the following: volume median diameter, 398±62 mum; number median diameter, 159±22 mum; droplet density, 22.5±7.0 droplets/cm² and estimated deposited volume, 22.2±9.4 L/ha. The respective ones reached with the computer program were: 402±58 mum, 161±32 mum, 21.9±7.5 droplets/cm² and 21.9±9.2 L/ha. Graphs of the spatial distribution of droplet density and deposited spray volume on the area were produced by the computer program.

  12. Classical and modern numerical analysis theory, methods and practice

    CERN Document Server

    Ackleh, Azmy S; Kearfott, R Baker; Seshaiyer, Padmanabhan

    2009-01-01

    Mathematical Review and Computer Arithmetic Mathematical Review Computer Arithmetic Interval ComputationsNumerical Solution of Nonlinear Equations of One Variable Introduction Bisection Method The Fixed Point Method Newton's Method (Newton-Raphson Method) The Univariate Interval Newton MethodSecant Method and Müller's Method Aitken Acceleration and Steffensen's Method Roots of Polynomials Additional Notes and SummaryNumerical Linear Algebra Basic Results from Linear Algebra Normed Linear Spaces Direct Methods for Solving Linear SystemsIterative Methods for Solving Linear SystemsThe Singular Value DecompositionApproximation TheoryIntroduction Norms, Projections, Inner Product Spaces, and Orthogonalization in Function SpacesPolynomial ApproximationPiecewise Polynomial ApproximationTrigonometric ApproximationRational ApproximationWavelet BasesLeast Squares Approximation on a Finite Point SetEigenvalue-Eigenvector Computation Basic Results from Linear Algebra The Power Method The Inverse Power Method Deflation T...

  13. Improved microscopical detection of acid-fast bacilli by the modified bleach method in lymphnode aspirates

    Directory of Open Access Journals (Sweden)

    Annam Vamseedhar

    2009-07-01

    Full Text Available Objectives: To improve the smear microscopy for detection of acid-fast bacilli (AFB in fine needle aspiration cytology (FNAC of lymph node using the bleach method and also to compare this with cytological diagnosis and the conventional Ziehl-Neelsen (ZN method. Study Design: In 99 consecutive patients with clinical suspicion of tuberculosis (TB presenting with lymphadenopathy, FNACs were performed. Smears from the aspirates were processed for routine cytology and the conventional ZN method. The remaining material in the needle hub and/or the syringe was used for the bleach method. The significance of the bleach method over the conventional ZN method and cytology was analyzed using the χ2 test. Results: Of 99 aspirates, 93 were studied and the remaining six were excluded from the study due to diagnosis of malignancy in 4.04% (4/6 and inadequate aspiration in 2.02% (2/6. Among the 93 aspirates, 33.33% (31/93 were positive for AFB on conventional ZN method, 41.94% (39/93 were indicative of TB on cytology and the smear positivity increased to 63.44% (59/93 on bleach method. Conclusion: The bleach method is simple, inexpensive and potent disinfectant, also limiting the risk of laboratory-acquired infections. The implementation of the bleach method clearly improves microscopic detection and can be a useful contribution to routine cytology.

  14. Laser apparatus and method for microscopic and spectroscopic analysis and processing of biological cells

    Science.gov (United States)

    Gourley, P.L.; Gourley, M.F.

    1997-03-04

    An apparatus and method are disclosed for microscopic and spectroscopic analysis and processing of biological cells. The apparatus comprises a laser having an analysis region within the laser cavity for containing one or more biological cells to be analyzed. The presence of a cell within the analysis region in superposition with an activated portion of a gain medium of the laser acts to encode information about the cell upon the laser beam, the cell information being recoverable by an analysis means that preferably includes an array photodetector such as a CCD camera and a spectrometer. The apparatus and method may be used to analyze biomedical cells including blood cells and the like, and may include processing means for manipulating, sorting, or eradicating cells after analysis. 20 figs.

  15. Reducing charging effects in scanning electron microscope images by Rayleigh contrast stretching method (RCS).

    Science.gov (United States)

    Wan Ismail, W Z; Sim, K S; Tso, C P; Ting, H Y

    2011-01-01

    To reduce undesirable charging effects in scanning electron microscope images, Rayleigh contrast stretching is developed and employed. First, re-scaling is performed on the input image histograms with Rayleigh algorithm. Then, contrast stretching or contrast adjustment is implemented to improve the images while reducing the contrast charging artifacts. This technique has been compared to some existing histogram equalization (HE) extension techniques: recursive sub-image HE, contrast stretching dynamic HE, multipeak HE and recursive mean separate HE. Other post processing methods, such as wavelet approach, spatial filtering, and exponential contrast stretching, are compared as well. Overall, the proposed method produces better image compensation in reducing charging artifacts. Copyright © 2011 Wiley Periodicals, Inc.

  16. Method for lateral force calibration in atomic force microscope using MEMS microforce sensor.

    Science.gov (United States)

    Dziekoński, Cezary; Dera, Wojciech; Jarząbek, Dariusz M

    2017-11-01

    In this paper we present a simple and direct method for the lateral force calibration constant determination. Our procedure does not require any knowledge about material or geometrical parameters of an investigated cantilever. We apply a commercially available microforce sensor with advanced electronics for direct measurement of the friction force applied by the cantilever's tip to a flat surface of the microforce sensor measuring beam. Due to the third law of dynamics, the friction force of the equal value tilts the AFM cantilever. Therefore, torsional (lateral force) signal is compared with the signal from the microforce sensor and the lateral force calibration constant is determined. The method is easy to perform and could be widely used for the lateral force calibration constant determination in many types of atomic force microscopes. Copyright © 2017 Elsevier B.V. All rights reserved.

  17. Olefination of carbonyl compounds: modern and classical methods

    Energy Technology Data Exchange (ETDEWEB)

    Korotchenko, V N; Nenajdenko, Valentine G; Balenkova, Elizabeth S [Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow (Russian Federation); Shastin, Aleksey V [Institute of Problems of Chemical Physics, Russian Academy of Sciences, Chernogolovka, Moscow Region (Russian Federation)

    2004-10-31

    The published data on the methods for alkene synthesis by olefination of carbonyl compounds are generalised and systematised. The main attention is given to the use of transition metals and organoelement compounds. The review covers the data on both classical and newly developed methods that are little known to chemists at large.

  18. Olefination of carbonyl compounds: modern and classical methods

    Science.gov (United States)

    Korotchenko, V. N.; Nenajdenko, Valentine G.; Balenkova, Elizabeth S.; Shastin, Aleksey V.

    2004-10-01

    The published data on the methods for alkene synthesis by olefination of carbonyl compounds are generalised and systematised. The main attention is given to the use of transition metals and organoelement compounds. The review covers the data on both classical and newly developed methods that are little known to chemists at large.

  19. ACARP Project C10059. ACARP manual of modern coal testing methods. Volume 1: The manual

    Energy Technology Data Exchange (ETDEWEB)

    Sakurovs, R.; Creelman, R.; Pohl, J.; Juniper, L. [CSIRO Energy Technology, Sydney, NSW (Australia)

    2002-07-01

    The Manual summarises the purpose, applicability, and limitations of a range of standard and modern coal testing methods that have potential to assist the coal company technologist to better evaluate coal performance. The first volume sets out the Modern Coal Testing Methods in summarised form that can be used as a quick guide to practitioners to assist in selecting the best technique to solve their problems.

  20. The awareness and use of modern contraceptive methods among ...

    African Journals Online (AJOL)

    ... and are increasingly being exposed to unplanned pregnancies with the attendant ... Few studies have been conducted among young women probably due to the ... Methods: It was a prospective, descriptive, cross-sectional study carried out ...

  1. Longitudinal data analysis a handbook of modern statistical methods

    CERN Document Server

    Fitzmaurice, Garrett; Verbeke, Geert; Molenberghs, Geert

    2008-01-01

    Although many books currently available describe statistical models and methods for analyzing longitudinal data, they do not highlight connections between various research threads in the statistical literature. Responding to this void, Longitudinal Data Analysis provides a clear, comprehensive, and unified overview of state-of-the-art theory and applications. It also focuses on the assorted challenges that arise in analyzing longitudinal data. After discussing historical aspects, leading researchers explore four broad themes: parametric modeling, nonparametric and semiparametric methods, joint

  2. MOLECULAR GENETIC MARKERS AND METHODS OF THEIR IDENTIFICATION IN MODERN FISH-FARMING

    Directory of Open Access Journals (Sweden)

    I. Hrytsyniak

    2014-03-01

    Full Text Available Purpose. The application of molecular genetic markers has been widely used in modern experimental fish-farming in recent years. This methodology is currently presented by a differentiated approach with individual mechanisms and clearly defined possibilities. Numerous publications in the scientific literature that are dedicated to molecular genetic markers for the most part offer purely practical data. Thus, the synthesis and analysis of existing information on the general principles of action and the limits of the main methods of using molecular genetic markers is an actual problem. In particular, such a description will make it possible to plan more effectively the experiment and to obtain the desired results with high reliability. Findings. The main types of variable parts of DNA that can be used as molecular genetic markers in determining the level of stock hybridization, conducting genetic inventory of population and solving other problems in modern fish-farming are described in this paper. Also, the article provides an overview of principal modern methods that can be used to identify molecular genetic markers. Originality. This work is a generalization of modern ideas about the mechanisms of experiments with molecular genetic markers in fish-farming. Information is provided in the form of consistent presentation of the principles and purpose of each method, as well as significant advances during their practical application. Practical value. The proposed review of classic and modern literature data on molecular genetic markers can be used for planning, modernization and correction of research activity in modern fish-farming.

  3. Modern methods for the synthesis of peptide-oligonucleotide conjugates

    International Nuclear Information System (INIS)

    Zubin, Evgenii M; Oretskaya, Tat'yana S; Romanova, Elena A

    2002-01-01

    The published data on the methods of chemical solution and solid-phase synthesis of peptide-oligonucleotide conjugates are reviewed. The known methods are systematised and their advantages and disadvantages are considered. The approaches to the solution synthesis of peptide-oligonucleotide conjugates are systematised according to the type of chemical bonds between the fragments, whereas those to the solid-phase synthesis are classified according to the procedure used for the preparation of conjugates, viz., stepwise elongation of oligonucleotide and peptide chains on the same polymeric support or solid-phase condensation of two presynthesised fragments. The bibliography includes 141 references.

  4. Oxygen Abundance Methods in SDSS: View from Modern Statistics ...

    Indian Academy of Sciences (India)

    6Occam's razor is a principle attributed to the 14th century English logician and .... knowledge of a galaxy's metallicity in order to locate it on the appropriate branch of ..... These methods try to balance the log likelihood term (lack of fit) with a.

  5. Modern methods of early diagnostics of juvenile arthritis

    Directory of Open Access Journals (Sweden)

    Chernenkov Y.V.

    2013-06-01

    Full Text Available The problem of inflammatory diseases of joints is one of the most important issues in the pediatrics. Nowadays the significant attention in this sphere is paid to the search of new accurate criteria of diagnostics. It will help estimate the severity of disease, determine the prognosis, choose the method of treatment and monitoring and evaluate the efficacy of the therapy.

  6. High accuracy mantle convection simulation through modern numerical methods

    KAUST Repository

    Kronbichler, Martin

    2012-08-21

    Numerical simulation of the processes in the Earth\\'s mantle is a key piece in understanding its dynamics, composition, history and interaction with the lithosphere and the Earth\\'s core. However, doing so presents many practical difficulties related to the numerical methods that can accurately represent these processes at relevant scales. This paper presents an overview of the state of the art in algorithms for high-Rayleigh number flows such as those in the Earth\\'s mantle, and discusses their implementation in the Open Source code Aspect (Advanced Solver for Problems in Earth\\'s ConvecTion). Specifically, we show how an interconnected set of methods for adaptive mesh refinement (AMR), higher order spatial and temporal discretizations, advection stabilization and efficient linear solvers can provide high accuracy at a numerical cost unachievable with traditional methods, and how these methods can be designed in a way so that they scale to large numbers of processors on compute clusters. Aspect relies on the numerical software packages deal.II and Trilinos, enabling us to focus on high level code and keeping our implementation compact. We present results from validation tests using widely used benchmarks for our code, as well as scaling results from parallel runs. © 2012 The Authors Geophysical Journal International © 2012 RAS.

  7. THE LONG ROAD TO THE USE OF MICROSCOPE IN CLINICAL MEDICINE IN VIVO: FROM EARLY PIONEERING PROPOSALS TO THE MODERN PERSPECTIVES OF OPTICAL BIOPSY

    OpenAIRE

    Ponti, Giovanni; Muscatello, Umberto

    2015-01-01

    For a long period the scientists did not recognized the potentialities of the compound microscope in medicine. Only few scientists recognized the potentialities of the microscope for the medicine; among them G. Campani who proposed the utilization of his microscope to investigate the skin lesions directly on the patient. The proposal was illustrated in a letter Acta Eruditorum of 1686. The recent development of optical techniques, capable of providing in-focus images of an object from differe...

  8. The long road to the use of microscope in clinical medicine in vivo: from early pioneering proposals to the modern perspectives of optical biopsy.

    Science.gov (United States)

    Ponti, Giovanni; Muscatello, Umberto; Sgantzos, Markos

    2015-01-01

    For a long period the scientists did not recognized the potentialities of the compound microscope in medicine. Only few scientists recognized the potentialities of the microscope for the medicine; among them G. Campani who proposed the utilization of his microscope to investigate the skin lesions directly on the patient. The proposal was illustrated in a letter Acta Eruditorum of 1686. The recent development of optical techniques, capable of providing in-focus images of an object from different planes with high spatial resolution, significantly increased the diagnostic potential of the microscope directly on the patient.

  9. A unit density method of grain analysis used to identify GABEergic neurons for electron microscopic autoradiographs

    International Nuclear Information System (INIS)

    Burry, R.W.

    1982-01-01

    The distribution of electron microscopic autoradiographic grains over neurons in cerebellar cultures incubated with [ 3 H]gamma-aminobutyric acid ([ 3 H]GABA) was examined. With the unit density method of grain analysis, the number of grains over each structure was tested against the total grain density for the entire section. If an individual structure has a grain density higher than the expected grain density, it is considered one of the group of heavily labeled structures. The expected grain density for each structure is calculated based on the area for that structure, the total grain density and the Poisson distribution. A different expected grain density can be calculated for any P value required. The method provides an adequate population of structures for morphological analysis but excludes weakly labeled structures and thus may underestimate the number of labeled structures. The unit density method of grain analysis showed, as expected, a group of cell bodies and synapses that was labeled heavily. Cultures incubated with other [ 3 H]amino acids did not have any heavily labeled synaptic elements. In addition, serial section analysis of sections showed that synapses heavily labeled with [ 3 H]GABA are seen in adjacent sections. The advantage of the unit density method of grain analysis is that it can be used to separate two groups of metabolically different neurons even when no morphological differences are present. (Auth.)

  10. AN INTELLIGENT NEURO-FUZZY TERMINAL SLIDING MODE CONTROL METHOD WITH APPLICATION TO ATOMIC FORCE MICROSCOPE

    Directory of Open Access Journals (Sweden)

    Seied Yasser Nikoo

    2016-11-01

    Full Text Available In this paper, a neuro-fuzzy fast terminal sliding mode control method is proposed for controlling a class of nonlinear systems with bounded uncertainties and disturbances. In this method, a nonlinear terminal sliding surface is firstly designed. Then, this sliding surface is considered as input for an adaptive neuro-fuzzy inference system which is the main controller. A proportinal-integral-derivative controller is also used to asist the neuro-fuzzy controller in order to improve the performance of the system at the begining stage of control operation. In addition, bee algorithm is used in this paper to update the weights of neuro-fuzzy system as well as the parameters of the proportinal-integral-derivative controller. The proposed control scheme is simulated for vibration control in a model of atomic force microscope system and the results are compared with conventional sliding mode controllers. The simulation results show that the chattering effect in the proposed controller is decreased in comparison with the sliding mode and the terminal sliding mode controllers. Also, the method provides the advantages of fast convergence and low model dependency compared to the conventional methods.

  11. Modern analytic methods applied to the art and archaeology

    International Nuclear Information System (INIS)

    Tenorio C, M. D.; Longoria G, L. C.

    2010-01-01

    The interaction of diverse areas as the analytic chemistry, the history of the art and the archaeology has allowed the development of a variety of techniques used in archaeology, in conservation and restoration. These methods have been used to date objects, to determine the origin of the old materials and to reconstruct their use and to identify the degradation processes that affect the integrity of the art works. The objective of this chapter is to offer a general vision on the researches that have been realized in the Instituto Nacional de Investigaciones Nucleares (ININ) in the field of cultural goods. A series of researches carried out in collaboration with national investigators and of the foreigner is described shortly, as well as with the great support of degree students and master in archaeology of the National School of Anthropology and History, since one of the goals that have is to diffuse the knowledge of the existence of these techniques among the young archaeologists, so that they have a wider vision of what they could use in an in mediate future and they can check hypothesis with scientific methods. (Author)

  12. Selected methods of waste monitoring using modern analytical techniques

    International Nuclear Information System (INIS)

    Hlavacek, I.; Hlavackova, I.

    1993-11-01

    Issues of the inspection and control of bituminized and cemented waste are discussed, and some methods of their nondestructive testing are described. Attention is paid to the inspection techniques, non-nuclear spectral techniques in particular, as employed for quality control of the wastes, waste concentrates, spent waste leaching solutions, as well as for the examination of environmental samples (waters and soils) from the surroundings of nuclear power plants. Some leaching tests used abroad for this purpose and practical analyses by the ICP-AES technique are given by way of example. The ICP-MS technique, which is unavailable in the Czech Republic, is routinely employed abroad for alpha nuclide measurements; examples of such analyses are also given. The next topic discussed includes the monitoring of organic acids and complexants to determine the degree of their thermal decomposition during the bituminization of wastes on an industrial line. All of the methods and procedures highlighted can be used as technical support during the monitoring of radioactive waste properties in industrial conditions, in the chemical and radiochemical analyses of wastes and related matter, in the calibration of nondestructive testing instrumentation, in the monitoring of contamination of the surroundings of nuclear facilities, and in trace analysis. (author). 10 tabs., 1 fig., 14 refs

  13. Modern spectrometric methods for the analysis of labelled compounds

    International Nuclear Information System (INIS)

    Kaspersen, F.M.; Funke, C.W.; Wagenaars, G.N.; Jacobs, P.L.

    1988-01-01

    A proper analysis of chemical compounds should give information about the chemical identity (not only the structure but also enantiomeric form), the chemical purity and chemical composition (e.g. giving information about counter-ions, solvents of crystallization). For labelled compounds information is also needed about isotopic purity (defined as the % of isotope present in the compound), the position/distribution of the isotope in the molecule and degree of labelling/specific activity. In the past ten years the possibilities for spectrometric analyses of labelled compounds have increased enormously and this chapter will give an overview of these methods with the exception of (radio)chromatography that will be dealt with in another chapter. (author)

  14. GLASS FIBERS – MODERN METHOD IN THE WOOD BEAMS REINFORCEMENT

    Directory of Open Access Journals (Sweden)

    Cătălina IANĂŞI

    2017-05-01

    Full Text Available : One of the defining goals of this paper is getting new resistant material which combine the qualities of basic materials that get into its composition but not to borrow from them their negative properties. Specifically, the use of GFRP composite materials as reinforcement for wood beams under bending loads requires paying attention to several aspects of the problem such as the number of the composite layers applied on the wood beams. The results obtained in this paper indicate that the behavior of reinforced beams is totally different from that of un-reinforced one. The main conclusion of the tests is that the tensioning forces allow beam taking a maximum load for a while, something that is particularly useful when we consider a real construction, The experiments have shown that the method of increasing resistance of wood constructions with composite materials is good for it and easy to implement.

  15. A Modern Method to Monitor Office Blood Pressure

    Directory of Open Access Journals (Sweden)

    Emiliya Khazan

    2017-10-01

    Full Text Available The diagnosis and management of hypertension relies on accurate and precise blood pressure (BP measurements and monitoring techniques. Variability in traditional office based BP readings can contribute to misclassification and potential misdiagnosis of hypertension, leading to inappropriate treatment and possibly avoidable adverse drug events. Both home blood pressure monitoring (HBPM and 24-hour ambulatory blood pressure monitoring (ABPM can improve characterization of BP status over traditional office values and can predict cardiovascular morbidity and mortality risk; however, they are limited by availability and/or practical use in many situations. Available in-office blood pressure measuring methods include manual auscultation, automated oscillometric, and automated office blood pressure (AOBP devices. A strong correlation exists between AOBP and awake ABPM measurements and has been linked to better prediction of end-organ damage and white coat response compared to standard office BP methods. While AOBP does not provide nocturnal BP readings, it can be utilized in several outpatient settings, and has the capability to decrease utilization of ABPM, white coat effect, and improve optimization of cardiovascular assessment, evaluation, and therapeutic assessment in clinical practice. Hypertension affects over 80 million adults in the United States (US and is a major risk factor for cardiovascular morbidity and mortality [1]. The condition’s ubiquitous nature and broad impact potentially makes understanding the diagnosis and treatment of hypertension key elements of managing cardiovascular risk. Though much attention is paid to the treatment of hypertension, from 2009 to 2012, 45.9% of US patients with hypertension were uncontrolled [1]. Appreciating the aspects of proper assessment of blood pressure is crucial and creates the foundation for approaching hypertension management. Until recently, hypertension was defined as an appropriately

  16. A scanning electron microscope method for automated, quantitative analysis of mineral matter in coal

    Energy Technology Data Exchange (ETDEWEB)

    Creelman, R.A.; Ward, C.R. [R.A. Creelman and Associates, Epping, NSW (Australia)

    1996-07-01

    Quantitative mineralogical analysis has been carried out in a series of nine coal samples from Australia, South Africa and China using a newly-developed automated image analysis system coupled to a scanning electron microscopy. The image analysis system (QEM{asterisk}SEM) gathers X-ray spectra and backscattered electron data from a number of points on a conventional grain-mount polished section under the SEM, and interprets the data from each point in mineralogical terms. The cumulative data in each case was integrated to provide a volumetric modal analysis of the species present in the coal samples, expressed as percentages of the respective coals` mineral matter. Comparison was made of the QEM{asterisk}SEM results to data obtained from the same samples using other methods of quantitative mineralogical analysis, namely X-ray diffraction of the low-temperature oxygen-plasma ash and normative calculation from the (high-temperature) ash analysis and carbonate CO{sub 2} data. Good agreement was obtained from all three methods for quartz in the coals, and also for most of the iron-bearing minerals. The correlation between results from the different methods was less strong, however, for individual clay minerals, or for minerals such as calcite, dolomite and phosphate species that made up only relatively small proportions of the mineral matter. The image analysis approach, using the electron microscope for mineralogical studies, has significant potential as a supplement to optical microscopy in quantitative coal characterisation. 36 refs., 3 figs., 4 tabs.

  17. Modern Methods for Modeling Change in Obesity Research in Nursing.

    Science.gov (United States)

    Sereika, Susan M; Zheng, Yaguang; Hu, Lu; Burke, Lora E

    2017-08-01

    Persons receiving treatment for weight loss often demonstrate heterogeneity in lifestyle behaviors and health outcomes over time. Traditional repeated measures approaches focus on the estimation and testing of an average temporal pattern, ignoring the interindividual variability about the trajectory. An alternate person-centered approach, group-based trajectory modeling, can be used to identify distinct latent classes of individuals following similar trajectories of behavior or outcome change as a function of age or time and can be expanded to include time-invariant and time-dependent covariates and outcomes. Another latent class method, growth mixture modeling, builds on group-based trajectory modeling to investigate heterogeneity within the distinct trajectory classes. In this applied methodologic study, group-based trajectory modeling for analyzing changes in behaviors or outcomes is described and contrasted with growth mixture modeling. An illustration of group-based trajectory modeling is provided using calorie intake data from a single-group, single-center prospective study for weight loss in adults who are either overweight or obese.

  18. [Evidence-based medicine: modern scientific methods for determining usefulness].

    Science.gov (United States)

    Schmidt, J G

    1999-01-01

    For quite some time, clinical epidemiology has introduced the art of critical appraisal of evidence as well as the methods of how to design sound clinical studies and trials. Almost unnoticed by most medical institutions a new hierarchy of evidence has emerged which puts well thought out trials, able to document unbiased treatment benefit in terms of patient suffering, above pathophysiological theory. Many controlled trials have shown, in the meantime, that the control of laboratory or other kind of pathologies and the correction of anatomical abnormalities do not necessarily mean a benefit for the patient. Concepts relating to this dissection of evidence include: Surrogate fallacy ("cosmetics" of laboratory results or ligament or cartilage "cosmetics" in surgery), confounding (spurious causal relationships), selection bias (comparison with selected groups) as well as lead-time bias (mistaking earlier diagnosis as increase of survival), length bias (overlooking differences in the aggressiveness of diseases as determinants of disease stage distributions) and overdiagnosis bias (mistaking the increasing detection of clinically silent pathologies as improvement of prognosis). Moreover, absolute instead of relative risk reduction needs to be used to measure patient benefit. The incorporation of decision-analysis and of the concepts or clinical epidemiology will improve the efficiency and quality of medicine much more effectively than the sole focus on technical medical performance. Evidence based medicine is the systematic and critical appraisal of medical interventions, based on the understanding how to avoid the fallacies and biases mentioned.

  19. A new method for the characterization of micro-/nano-periodic structures based on microscopic Moiré fringes

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Dan; Xie, Huimin, E-mail: xiehm@mail.tsinghua.edu.cn; Tang, Minjin; Hu, Zhenxing

    2014-01-15

    Linewidth and opening ratio (ratio of linewidth to period) are important parameters in characterizing micro-/nano-periodic and quasi-periodic structures. Periodic structures are conventionally characterized by the direct observation of specimens under a microscope. However, the field of view is relatively small, and only certain details can be acquired under a microscope. Moreover, the non-uniformity of the linewidth in quasi-periodic structures cannot be detected. This paper proposes a new characterization method for determining the linewidth and opening ratio of periodic structures based on Moiré fringe analysis. This method has the advantage of full-field characterization of the linewidth of micro-/nano-structures over a larger area than that afforded by direct observation. To validate the method, the linewidth of scanning electron microscope (SEM) scan lines was first calibrated with a standard grating. Next, a microperiodic structure with known geometry was characterized using this calibrated SEM system. The results indicate that the proposed method is simple and effective, indicating a potential approach for the characterization of gratings over large areas. This technique can be extended to various high-power scanning microscopes to characterize micro-/nano-structures. - Highlights: • A characterization method of the linewidth of high frequency gratings based on the microscope Moiré fringes is introduced. • The principle is according to the geometrical relationship between the gratings and the Moiré fringes. • This method has the potential application in characterization of the micro-/nano-structures. • The advantage of this method is that the micro-/nano-structures can be characterized in large view field under the full field of the microscope. • The microstructure of a butterfly has been characterized to declare the feasibility of this method.

  20. Modern diagnostic method of microelementosis of school age children

    International Nuclear Information System (INIS)

    Rasulov, S.K.

    2006-01-01

    Full text: Human and animal pathology stipulated by deficiency of vitally important (or 'essential') microelements or their excess, has got its combined name microelementosis [1]. In connection with high biological activity of microelements in organism in different physiologic and pathologic status the quantitative determination of several metals in biomedium of organism is of great importance in the study of microelement metabolism. However, objective and representative data on estimation of school children's provision with microelements are practically absent. The objective of the study was to investigate contents of microelements connected with deficiency of biometals participating in hemopoiesis (Cu, Zn, Co, Mn) in biomedium of the organism of school children in Zarafshan region of the Republic of Uzbekistan. We have applied the method of neutron-activation analysis for determination of microelements (Fe, Zn, Cu, Co, Mn) in hair, whole blood, blood serum, urine, saliva, food-stuff samples and in more than 20 elements of other biomedia, as per designed method in Nuclear Physics Institute, Republic of Uzbekistan [4]. The study was carried out on 245 practically healthy children aged 7-17, 131 boys and 33 girls living in four different areas of Samarkand region. According to the designed method the determination of Mn, Cu was done as follows: samples together with standards were packed in polyethylene container and underwent irradiation in vertical channel of the reactor by neutron flow 5x10 13 neutron cm -2 sec - 1 , (for 15 seconds). The measurement of direct activity was conducted in 2 hours for determining of Cu and Mn. For determining of iron, cobalt, zinc the irradiation test measurement was done within 15 hours one month after irradiation by the corresponding radionuclides. In all measurement of element contents different standards were applied: Intralaboratory data was received by fixing a certain number of elements on ashless filter paper and comparison

  1. [Cognitive functions, their development and modern diagnostic methods].

    Science.gov (United States)

    Klasik, Adam; Janas-Kozik, Małgorzata; Krupka-Matuszczyk, Irena; Augustyniak, Ewa

    2006-01-01

    provided a theory. The psychometric approach concentrates on studying the differences in intelligence. The aim of this approach is to test intelligence by means of standardized tests (e.g. WISC-R, WAIS-R) used to show the individual differences among humans. Human cognitive functions determine individuals' adaptation capabilities and disturbances in this area indicate a number of psychopathological changes and are a symptom enabling to differentiate or diagnose one with a disorder. That is why the psychological assessment of cognitive functions is an important part of patients' diagnosis. Contemporary neuropsychological studies are to a great extent based computer tests. The use of computer methods has a number of measurement-related advantages. It allows for standardized testing environment, increasing therefore its reliability and standardizes the patient assessment process. Special attention should be paid to the neuropsychological tests included in the Vienna Test System (Cognitron, SIGNAL, RT, VIGIL, DAUF), which are used to assess the operational memory span, learning processes, reaction time, attention selective function, attention continuity as well as attention interference resistance. It also seems justified to present the CPT id test (Continuous Performance Test) as well as Free Recall. CPT is a diagnostic tool used to assess the attention selective function, attention continuity of attention, attention interference resistance as well as attention alertness. The Free Recall test is used in the memory processes diagnostics to assess patients' operational memory as well as the information organization degree in operational memory. The above mentioned neuropsychological tests are tools used in clinical assessment of cognitive function disorders.

  2. Evaluation of Enterococcus faecalis adhesion, penetration, and method to prevent the penetration of Enterococcus faecalis into root cementum: Confocal laser scanning microscope and scanning electron microscope analysis.

    Science.gov (United States)

    Halkai, Rahul S; Hegde, Mithra N; Halkai, Kiran R

    2016-01-01

    To ascertain the role of Enterococcus faecalis in persistent infection and a possible method to prevent the penetration of E. faecalis into root cementum. One hundred and twenty human single-rooted extracted teeth divided into five groups. Group I (control): intact teeth, Group II: no apical treatment done, Group III divided into two subgroups. In Groups IIIa and IIIb, root apex treated with lactic acid of acidic and neutral pH, respectively. Group IV: apical root cementum exposed to lactic acid and roughened to mimic the apical resorption. Group V: apical treatment done same as Group IV and root-end filling done using mineral trioxide aggregate (MTA). Apical one-third of all samples immersed in E. faecalis broth for 8 weeks followed by bone morphogenetic protein and obturation and again immersed into broth for 8 weeks. Teeth split into two halves and observed under confocal laser scanning microscope and scanning electron microscope, organism identified by culture and polymerase chain reaction techniques. Adhesion and penetration was observed in Group IIIa and Group IV. Only adhesion in Group II and IIIB and no adhesion and penetration in Group I and V. Adhesion and penetration of E. faecalis into root cementum providing a long-term nidus for subsequent infection are the possible reason for persistent infection and root-end filling with MTA prevents the adhesion and penetration.

  3. [Reasearch on evolution and transition of processing method of fuzi in ancient and modern times].

    Science.gov (United States)

    Liu, Chan-Chan; Cheng, Ming-En; Duan, Hai-Yan; Peng, Hua-Sheng

    2014-04-01

    Fuzi is a medicine used for rescuing from collapse by restoring yang as well as a famous toxic traditional Chinese medicine. In order to ensure the efficacy and safe medication, Fuzi has mostly been applied after being processed. There have been different Fuzi processing methods recorded by doctors of previous generations. Besides, there have also been differences in Fuzi processing methods recorded in modern pharmacopeia and ancient medical books. In this study, the authors traced back to medical books between the Han Dynasty and the period of Republic of China, and summarized Fuzi processing methods collected in ancient and modern literatures. According to the results, Fuzi processing methods and using methods have changed along with the evolution of dynasties, with differences in ancient and modern processing methods. Before the Tang Dynasty, Fuzi had been mostly processed and soaked. From Tang to Ming Dynasties, Fuzi had been mostly processed, soaked and stir-fried. During the Qing Dynasty, Fuzi had been mostly soaked and boiled. In the modem times, Fuzi is mostly processed by being boiled and soaked. Before the Tang Dynasty, a whole piece of Fuzi herbs or their fragments had been applied in medicines; Whereas their fragments are primarily used in the modern times. Because different processing methods have great impacts on the toxicity of Fuzi, it is suggested to study Fuzi processing methods.

  4. ACARP Project C10059. ACARP manual of modern coal testing methods. Volume 2: Appendices

    Energy Technology Data Exchange (ETDEWEB)

    Sakurovs, R.; Creelman, R.; Pohl, J.; Juniper, L. [CSIRO Energy Technology, Sydney, NSW (Australia)

    2002-07-01

    The Manual summarises the purpose, applicability, and limitations of a range of standard and modern coal testing methods that have potential to assist the coal company technologist to better evaluate coal performance. It is presented in two volumes. This second volume provides more detailed information regarding the methods discussed in Volume 1.

  5. The Innovation Blaze-Method of Development Professional Thinking Designers in the Modern Higher Education

    Science.gov (United States)

    Alekseeva, Irina V.; Barsukova, Natalia I.; Pallotta, Valentina I.; Skovorodnikova, Nadia A.

    2017-01-01

    This article proved the urgency of the problem of development of professional thinking of students studying design in modern conditions of higher education. The authors substantiate for the need of an innovative Blaise-method development of professional design thinking of students in higher education. "Blaise-method" named by us in…

  6. A multiple-well method for immunohistochemical testing of many reagents on a single microscopic slide.

    Science.gov (United States)

    McKeever, P E; Letica, L H; Shakui, P; Averill, D R

    1988-09-01

    Multiple wells (M-wells) have been made over tissue sections on single microscopic slides to simultaneously localize binding specificity of many antibodies. More than 20 individual 4-microliter wells over tissue have been applied/slide, representing more than a 5-fold improvement in wells/slide and a 25-fold reduction in reagent volume over previous methods. More than 30 wells/slide have been applied over cellular monolayers. To produce the improvement, previous strategies of placing specimens into wells were changed to instead create wells over the specimen. We took advantage of the hydrophobic properties of paint to surround the wells and to segregate the various different primary antibodies. Segregation was complete on wells alternating with and without primary monoclonal antibody. The procedure accommodates both frozen and paraffin sections, yielding slides which last more than a year. After monoclonal antibody detection, standard histologic stains can be applied as counterstains. M-wells are suitable for localizing binding of multiple reagents or sample unknowns (polyclonal or monoclonal antibodies, hybridoma supernatants, body fluids, lectins) to either tissues or cells. Their small sample volume and large number of sample wells/slide could be particularly useful for early screening of hybridoma supernatants and for titration curves in immunohistochemistry (McKeever PE, Shakui P, Letica LH, Averill DR: J Histochem Cytochem 36:931, 1988).

  7. A simple method for environmental cell depressurization for use with an electron microscope.

    Science.gov (United States)

    Ogawa, Naoki; Mizokawa, Ryo; Saito, Minoru; Ishikawa, Akira

    2017-12-01

    With the aid of the environmental cell (EC) in electron microscopy, hydrated specimens have been observed at high resolutions that optical microscopy cannot attain. Due to the ultra-high vacuum conditions of the inner column of the electron microscope, the EC requires sealing films that are sufficiently thin to allow electron transmission and that are sufficiently tough to withstand the pressure difference between the inside and outside of the EC. However, most hydrated specimens can be observed at low vacuum because the saturated vapor pressure of water is known to be 0.02 atm at room temperature. These concepts have been used in the differential pumping system, but it is complicated and relatively expensive. In this work, we propose a simple method for depressurization of the EC using a 'balloon structure' and demonstrate the theoretical benefits and practical improvement for specimen observations in low-vacuum conditions. © The Author 2017. Published by Oxford University Press on behalf of The Japanese Society of Microscopy. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  8. Modern methods of surveyor observations in opencast mining under complex hydrogeological conditions.

    Science.gov (United States)

    Usoltseva, L. A.; Lushpei, V. P.; Mursin, VA

    2017-10-01

    The article considers the possibility of linking the modern methods of surveying security of open mining works to improve industrial safety in the Primorsky Territory, as well as their use in the educational process. Industrial Safety in the management of Surface Mining depends largely on the applied assessment methods and methods of stability of pit walls and slopes of dumps in the complex mining and hydro-geological conditions.

  9. A Literature Review Fuzzy Pay-Off-Method – A Modern Approach in Valuation

    Directory of Open Access Journals (Sweden)

    Daniel Manaţe

    2015-01-01

    Full Text Available This article proposes to present a modern approach in the analysis of updated cash flows. The approach is based on the Fuzzy Pay-Off-Method (FPOM for Real Option Valuation (ROV. This article describes a few types of models for the valuation of real options currently in use. In support for the chosen FPOM method, we included the mathematical model that stands at the basis of this method and a case study.

  10. The perturbed angular correlation method - a modern technique in studying solids

    International Nuclear Information System (INIS)

    Unterricker, S.; Hunger, H.J.

    1979-01-01

    Starting from theoretical fundamentals the differential perturbed angular correlation method has been explained. By using the probe nucleus 111 Cd the magnetic dipole interaction in Fesub(x)Alsub(1-x) alloys and the electric quadrupole interaction in Cd have been measured. The perturbed angular correlation method is a modern nuclear measuring method and can be applied in studying ordering processes, phase transformations and radiation damages in metals, semiconductors and insulators

  11. Optical forces, torques, and force densities calculated at a microscopic level using a self-consistent hydrodynamics method

    Science.gov (United States)

    Ding, Kun; Chan, C. T.

    2018-04-01

    The calculation of optical force density distribution inside a material is challenging at the nanoscale, where quantum and nonlocal effects emerge and macroscopic parameters such as permittivity become ill-defined. We demonstrate that the microscopic optical force density of nanoplasmonic systems can be defined and calculated using the microscopic fields generated using a self-consistent hydrodynamics model that includes quantum, nonlocal, and retardation effects. We demonstrate this technique by calculating the microscopic optical force density distributions and the optical binding force induced by external light on nanoplasmonic dimers. This approach works even in the limit when the nanoparticles are close enough to each other so that electron tunneling occurs, a regime in which classical electromagnetic approach fails completely. We discover that an uneven distribution of optical force density can lead to a light-induced spinning torque acting on individual particles. The hydrodynamics method offers us an accurate and efficient approach to study optomechanical behavior for plasmonic systems at the nanoscale.

  12. Some aspects of Trim-algorithm modernization for Monte-Carlo method

    International Nuclear Information System (INIS)

    Dovnar, S.V.; Grigor'ev, V.V.; Kamyshan, M.A.; Leont'ev, A.V.; Yanusko, S.V.

    2001-01-01

    Some aspects of Trim-algorithm modernization in Monte-Carlo method are discussed. This modification permits to raise the universality of program work with various potentials of ion-atom interactions and to improve the calculation precision for scattering angle θ c

  13. International Conference on Modern Mathematical Methods and High Performance Computing in Science and Technology

    CERN Document Server

    Srivastava, HM; Venturino, Ezio; Resch, Michael; Gupta, Vijay

    2016-01-01

    The book discusses important results in modern mathematical models and high performance computing, such as applied operations research, simulation of operations, statistical modeling and applications, invisibility regions and regular meta-materials, unmanned vehicles, modern radar techniques/SAR imaging, satellite remote sensing, coding, and robotic systems. Furthermore, it is valuable as a reference work and as a basis for further study and research. All contributing authors are respected academicians, scientists and researchers from around the globe. All the papers were presented at the international conference on Modern Mathematical Methods and High Performance Computing in Science & Technology (M3HPCST 2015), held at Raj Kumar Goel Institute of Technology, Ghaziabad, India, from 27–29 December 2015, and peer-reviewed by international experts. The conference provided an exceptional platform for leading researchers, academicians, developers, engineers and technocrats from a broad range of disciplines ...

  14. Direct measurement of surface-state conductance by microscopic four-point probe method

    DEFF Research Database (Denmark)

    Hasegawa, S.; Shiraki, I.; Tanikawa, T.

    2002-01-01

    For in situ measurements of local electrical conductivity of well defined crystal surfaces in ultrahigh vacuum, we have developed microscopic four-point probes with a probe spacing of several micrometres, installed in a scanning-electron - microscope/electron-diffraction chamber. The probe...... is precisely positioned on targeted areas of the sample surface by using piezoactuators. This apparatus enables conductivity measurement with extremely high surface sensitivity, resulting in direct access to surface-state conductivity of the surface superstructures, and clarifying the influence of atomic steps...

  15. Advance in quality assessment of Chinese materia medica using microscopic and morphological methods.

    Science.gov (United States)

    Miao, Xiao-Su; Cui, Qing-Yu; Wang, Zhao-Yi; Liu, Xiao-Na; Zhao, An-Bang; Qiao, Yan-Jiang; Wu, Zhi-Sheng

    2017-09-01

    Quality evaluation plays a vital role in ensuring safety and effectiveness of Chinese materia medica (CMM). Microscopic and morphological technologies can be used to distinguish CMM's characteristics, such as shape, size, texture, section, and smell, for authenticity and quality control of CMM. The microscopic and morphological applications of novel micro-technology, colorimeter, and texture analyzer for CMM identification are summarized and the future prospect is discussed in this paper. Various styles and complex sources of CMM are systemically reviewed, including cormophyte medicinal materials, fruit and seeds, pollen grain, and spore materials. Copyright © 2017 China Pharmaceutical University. Published by Elsevier B.V. All rights reserved.

  16. A simple but precise method for quantitative measurement of the quality of the laser focus in a scanning optical microscope.

    Science.gov (United States)

    Trägårdh, J; Macrae, K; Travis, C; Amor, R; Norris, G; Wilson, S H; Oppo, G-L; McConnell, G

    2015-07-01

    We report a method for characterizing the focussing laser beam exiting the objective in a laser scanning microscope. This method provides the size of the optical focus, the divergence of the beam, the ellipticity and the astigmatism. We use a microscopic-scale knife edge in the form of a simple transmission electron microscopy grid attached to a glass microscope slide, and a light-collecting optical fibre and photodiode underneath the specimen. By scanning the laser spot from a reflective to a transmitting part of the grid, a beam profile in the form of an error function can be obtained and by repeating this with the knife edge at different axial positions relative to the beam waist, the divergence and astigmatism of the postobjective laser beam can be obtained. The measured divergence can be used to quantify how much of the full numerical aperture of the lens is used in practice. We present data of the beam radius, beam divergence, ellipticity and astigmatism obtained with low (0.15, 0.7) and high (1.3) numerical aperture lenses and lasers commonly used in confocal and multiphoton laser scanning microscopy. Our knife-edge method has several advantages over alternative knife-edge methods used in microscopy including that the knife edge is easy to prepare, that the beam can be characterized also directly under a cover slip, as necessary to reduce spherical aberrations for objectives designed to be used with a cover slip, and it is suitable for use with commercial laser scanning microscopes where access to the laser beam can be limited. © 2015 The Authors Journal of Microscopy © 2015 Royal Microscopical Society.

  17. Introduction to modern methods of quantum many-body theory and their applications

    CERN Document Server

    Fantoni, Stefano; Krotscheck, Eckhard S

    2002-01-01

    This invaluable book contains pedagogical articles on the dominant nonstochastic methods of microscopic many-body theories - the methods of density functional theory, coupled cluster theory, and correlated basis functions - in their widest sense. Other articles introduce students to applications of these methods in front-line research, such as Bose-Einstein condensates, the nuclear many-body problem, and the dynamics of quantum liquids. These keynote articles are supplemented by experimental reviews on intimately connected topics that are of current relevance. The book addresses the striking l

  18. METHODS OF TRAINING OF MODERN AIRCRAFT FLIGHT CREWS FOR INFLIGHT ABNORMAL CIRCUMSTANCES

    Directory of Open Access Journals (Sweden)

    Yurii Hryshchenko

    2017-03-01

    Full Text Available Purpose: The purpose of this article is the theoretical justification of the existing methods and development of new methods of training the crews of modern aircraft for inflight abnormal circumstances. Methods: The article describes the research methods of engineering psychology, mathematical statistics and analysis of the correlation functions. Results: The example of the two accidents of aircraft with modern avionics is shown in the problem statement. The pilot made a sharp movement of the steering wheel while go-around, which has led to a sharp diving and impossibility of coming out of it. It was shown that the developed anti-stress training methods allow crews to train a human operator to prevent such events. The theoretical solution of the problem of optimization of the flight on the final approach, considering the human factor, is suggested to solve using the method of analysis of the autocorrelation function. Conclusions: It is necessary to additionally implement methods of teaching the counteracting of factorial overlaps into the training course using the complex modern aircraft simulators. It is enough to analyze a single pitch angle curve of the autocorrelation function to determine the phenomena of amplification of integral-differential motor dynamic stereotype of the pilot.

  19. Modern nuclear medicine methods as a topic of biophysics in veterinary training at UVM in Kosice

    International Nuclear Information System (INIS)

    Stanicova, J.; Lohajova, L.

    2004-01-01

    Diagnostic and therapeutic application of ionising radiation is very important in all of branches of medicine including veterinary medicine. In veterinary training at University of Veterinary Medicine in Kosice (UVM), biophysics is a basic subject and it grants physical basis necessary for understanding subsequent subjects such as veterinary surgery, roentgenology, orthopedics. In view of this, traditional methods of radiology such as fluoroscopy, skiagraphy and tomography are explaining. The appearance and application of the theory so called reconstruction of image and also computers led to qualitatively new solutions via the development of modern methods in radiology. Explaining of physical principles, advantages or disadvantages of these new methods is also important in veterinary training although some of them do not use in veterinary practice yet. Two modern methods of nuclear medicine using in diagnostic (SPECT and PET) are discussed bellow. (authors)

  20. Place of modern imaging methods and their influence on the diagnostic process

    International Nuclear Information System (INIS)

    Petkov, D.; Lazarova, I.

    1991-01-01

    The main trends in development of the modern imaging diagnostic methods are presented: increasing the specificity of CT, nuclear-magnetic resonance imaging, positron-emission tomography, digital substractional angiography, echography etc. based on modern technical improvements; objective representation of the physiological and biochemical divergencies in particular diseases; interventional radiology; integral application of different methods; improving the sensitivity and specificity of the methods based on developments in pharmacology (new contrast media, parmaceuticals influencing the function of examinated organs, etc.); the possibilities for data compilation and further computerized processing of primary data. Personal experience is reported with the exploitation of these methods in Bulgaria. Attention is also called to the unfavourable impact connected with the too strong technicization of the diagnostic and therapeutic process in a health, deontologic, economical and social respect. 15 refs

  1. Discounted Cash Flow and Modern Asset Pricing Methods - Project Selection and Policy Implications

    Energy Technology Data Exchange (ETDEWEB)

    Emhjellen, Magne; Alaouze, Chris M.

    2002-07-01

    We examine the differences in the net present values (NPV's) of North Sea oil projects obtained using the Weighted Average Cost of Capital (WACC) and a Modern Asset Pricing (MAP) method which involves the separate discounting of project cash flow components. NPV differences of more than $1 Om were found for some oil projects. Thus, the choice of valuation method will affect the development decisions of oil companies. The results of the MAP method are very sensitive to the choice of parameter values for the stochastic process used to model oil prices. Further research is recommended before the MAP method is used as the sole valuation model. (author)

  2. Discounted Cash Flow and Modern Asset Pricing Methods - Project Selection and Policy Implications

    International Nuclear Information System (INIS)

    Emhjellen, Magne; Alaouze, Chris M.

    2002-01-01

    We examine the differences in the net present values (NPV's) of North Sea oil projects obtained using the Weighted Average Cost of Capital (WACC) and a Modern Asset Pricing (MAP) method which involves the separate discounting of project cash flow components. NPV differences of more than $1 Om were found for some oil projects. Thus, the choice of valuation method will affect the development decisions of oil companies. The results of the MAP method are very sensitive to the choice of parameter values for the stochastic process used to model oil prices. Further research is recommended before the MAP method is used as the sole valuation model. (author)

  3. Discounted Cash Flow and Modern Asset Pricing Methods - Project Selection and Policy Implications

    Energy Technology Data Exchange (ETDEWEB)

    Emhjellen, Magne; Alaouze, Chris M

    2002-07-01

    We examine the differences in the net present values (NPV's) of North Sea oil projects obtained using the Weighted Average Cost of Capital (WACC) and a Modern Asset Pricing (MAP) method which involves the separate discounting of project cash flow components. NPV differences of more than $1 Om were found for some oil projects. Thus, the choice of valuation method will affect the development decisions of oil companies. The results of the MAP method are very sensitive to the choice of parameter values for the stochastic process used to model oil prices. Further research is recommended before the MAP method is used as the sole valuation model. (author)

  4. A comparison of discounted cashflow and modern asset pricing methods - project selection and policy implications

    International Nuclear Information System (INIS)

    Emhjellen, Magne; Alaouze, Chris M.

    2003-01-01

    We examine the differences in the net present values (NPVs) of North Sea oil projects obtained using the weighted average cost of capital and a modern asset pricing (MAP) method which involves the separate discounting of project cashflow components. NPV differences of more than $10 million were found for some oil projects. Thus, the choice of valuation method will affect the development decisions of oil companies and could influence tax policy. The results of the MAP method are very sensitive to the choice of parameter values for the stochastic process used to model oil prices. Further research is recommended before the MAP method is used as the sole valuation model

  5. Distinguishing the Chinese materia medica Tiepishihu from similar Dendrobium species of the same genus using histological and microscopic method.

    Science.gov (United States)

    Yu, Kun-Zi; Yan, Hua; Tai, Hai-Chuan; Zhang, Nan-Ping; Cheng, Xian-Long; Guo, Zeng-Xi; Ma, Shuang-Cheng; Wei, Feng

    2017-07-01

    The Chinese Materia Medica, Tiepishihu, used as a tonic for over one thousand years, is a well-known precious medicine in China. According to the Chinese Pharmacopoeia, its source is the species Dendrobium officinale Kimura et Migo, which is distinguished from other species in Dendrobium genus. However, these species from the same genus are similar with Tiepishihu and caused confusion in the market. To find a quick and simple method to distinguish Tiepishihu from other similar species, histologic and microscopic methods were combined together to investigate the transverse section of stem of Tiepishihu and other similar species. Phloroglucinol test solution with hydrochloric acid was used to reveal the lignified tissue by staining the transverse section of Tiepishihu and similar species. Results revealed the unique identification characteristics to distinguish Tiepishihu from similar species, which were difficult to distinguish by other methods. The identification characteristics of Tiepishihu include the cells of vascular bundle sheath were stained red, parenchyma cells were not stained red. What's more, other species can be distinguished from each other with microscopic and histological characteristics. These characteristics proved stable and can be easily observed by normal light microscopic examination. This method is rapid, accurate, stable, and inexpensive. © 2017 Wiley Periodicals, Inc.

  6. Methods of geometric function theory in classical and modern problems for polynomials

    International Nuclear Information System (INIS)

    Dubinin, Vladimir N

    2012-01-01

    This paper gives a survey of classical and modern theorems on polynomials, proved using methods of geometric function theory. Most of the paper is devoted to results of the author and his students, established by applying majorization principles for holomorphic functions, the theory of univalent functions, the theory of capacities, and symmetrization. Auxiliary results and the proofs of some of the theorems are presented. Bibliography: 124 titles.

  7. Review of Polynomial Chaos-Based Methods for Uncertainty Quantification in Modern Integrated Circuits

    OpenAIRE

    Arun Kaintura; Tom Dhaene; Domenico Spina

    2018-01-01

    Advances in manufacturing process technology are key ensembles for the production of integrated circuits in the sub-micrometer region. It is of paramount importance to assess the effects of tolerances in the manufacturing process on the performance of modern integrated circuits. The polynomial chaos expansion has emerged as a suitable alternative to standard Monte Carlo-based methods that are accurate, but computationally cumbersome. This paper provides an overview of the most recent developm...

  8. The role of classical and modern teaching methods in business education

    Directory of Open Access Journals (Sweden)

    Conțu Eleonora Gabriela

    2017-07-01

    Full Text Available Nowadays the training-educational process is a dynamic and complex process which uses both classical and modern teaching methods in order to obtain performance in education. Even though traditional teaching methods have a formal character interaction between teacher and students, this is face-to-face and therefore students can give an immediate feedback. From this point of view classical teaching methods are important from time to time. In Romania, in the European context the role of effective learning strategies represents the key point for the education process. The role of teachers in developing creativity to those students who want to learn in an interactive way is very important because they should imply that students directly in the training -educational process. In this context the educational process must be student centered because only in this way their critical thinking and creativity is developed. We can say that when non-formal and informal learning is combined with formal learning the scope of pedagogy is accomplish. In contemporary context education is regarded as an innovative concept which is used to produce performance at the individual level and also, at institutional level, education provides support in order to build strategies according to the challenges from the labour market. The paper is based on a qualitative research, conducted on a sample of 100 people aged between 19 and 23 years old (students at a Business School. The key question raised at this point is: What is the role of classical and modern teaching methods in training-educational process? The objectives of this study are the following: 1. highlighting the context of higher education in Romania; 2. presenting the role of university strategy in contemporary context; 3. highlighting the importance of using classical/modern teaching methods in business education; 4. presenting the role of innovation and creativity in business education; 5. presenting the analysis

  9. The application of modern nodal methods to PWR reactor physics analysis

    International Nuclear Information System (INIS)

    Knight, M.P.

    1988-06-01

    The objective of this research is to develop efficient computational procedures for PWR reactor calculations, based on modern nodal methods. The analytic nodal method, which is characterised by the use of exact exponential expansions in transverse-integrated equations, is implemented within an existing finite-difference code. This shows considerable accuracy and efficiency on standard benchmark problems, very much in line with existing experience with nodal methods., Assembly powers can be calculated to within 2.0% with just one mesh per assembly. (author)

  10. Near-infrared microscopic methods for the detection and quantification of processed by-products of animal origin

    Science.gov (United States)

    Abbas, O.; Fernández Pierna, J. A.; Dardenne, P.; Baeten, V.

    2010-04-01

    Since the BSE crisis, researches concern mainly the detection, identification, and quantification of meat and bone meal with an important focus on the development of new analytical methods. Microscopic based spectroscopy methods (NIR microscopy - NIRM or/and NIR hyperspectral imaging) have been proposed as complementary methods to the official method; the optical microscopy. NIR spectroscopy offers the advantage of being rapid, accurate and independent of human analyst skills. The combination of an NIR detector and a microscope or a camera allows the collection of high quality spectra for small feed particles having a size larger than 50 μm. Several studies undertaken have demonstrated the clear potential of NIR microscopic methods for the detection of animal particles in both raw and sediment fractions. Samples are sieved and only the gross fraction (superior than 250 μm) is investigated. Proposed methodologies have been developed to assure, with an acceptable level of confidence (95%), the detection of at least one animal particle when a feed sample is adulterated at a level of 0.1%. NIRM and NIR hyperspectral imaging are running under accreditation ISO 17025 since 2005 at CRA-W. A quantitative NIRM approach has been developed in order to fulfill the new requirements of the European commission policies. The capacities of NIRM method have been improved; only the raw fraction is analyzed, both the gross and the fine fractions of the samples are considered, and the acquisition parameters are optimized (the aperture, the gap, and the composition of the animal feed). A mapping method for a faster collection of spectra is also developed. The aim of this work is to show the new advances in the analytical methods developed in the frame of the feed ban applied in Europe.

  11. Applications of modern statistical methods to analysis of data in physical science

    Science.gov (United States)

    Wicker, James Eric

    Modern methods of statistical and computational analysis offer solutions to dilemmas confronting researchers in physical science. Although the ideas behind modern statistical and computational analysis methods were originally introduced in the 1970's, most scientists still rely on methods written during the early era of computing. These researchers, who analyze increasingly voluminous and multivariate data sets, need modern analysis methods to extract the best results from their studies. The first section of this work showcases applications of modern linear regression. Since the 1960's, many researchers in spectroscopy have used classical stepwise regression techniques to derive molecular constants. However, problems with thresholds of entry and exit for model variables plagues this analysis method. Other criticisms of this kind of stepwise procedure include its inefficient searching method, the order in which variables enter or leave the model and problems with overfitting data. We implement an information scoring technique that overcomes the assumptions inherent in the stepwise regression process to calculate molecular model parameters. We believe that this kind of information based model evaluation can be applied to more general analysis situations in physical science. The second section proposes new methods of multivariate cluster analysis. The K-means algorithm and the EM algorithm, introduced in the 1960's and 1970's respectively, formed the basis of multivariate cluster analysis methodology for many years. However, several shortcomings of these methods include strong dependence on initial seed values and inaccurate results when the data seriously depart from hypersphericity. We propose new cluster analysis methods based on genetic algorithms that overcomes the strong dependence on initial seed values. In addition, we propose a generalization of the Genetic K-means algorithm which can accurately identify clusters with complex hyperellipsoidal covariance

  12. Development of new methods in modern selective organic synthesis: preparation of functionalized molecules with atomic precision

    International Nuclear Information System (INIS)

    Ananikov, V P; Khemchyan, L L; Ivanova, Yu V; Dilman, A D; Levin, V V; Bukhtiyarov, V I; Sorokin, A M; Prosvirin, I P; Romanenko, A V; Simonov, P A; Vatsadze, S Z; Medved'ko, A V; Nuriev, V N; Nenajdenko, V G; Shmatova, O I; Muzalevskiy, V M; Koptyug, I V; Kovtunov, K V; Zhivonitko, V V; Likholobov, V A

    2014-01-01

    The challenges of the modern society and the growing demand of high-technology sectors of industrial production bring about a new phase in the development of organic synthesis. A cutting edge of modern synthetic methods is introduction of functional groups and more complex structural units into organic molecules with unprecedented control over the course of chemical transformation. Analysis of the state-of-the-art achievements in selective organic synthesis indicates the appearance of a new trend — the synthesis of organic molecules, biologically active compounds, pharmaceutical substances and smart materials with absolute selectivity. Most advanced approaches to organic synthesis anticipated in the near future can be defined as 'atomic precision' in chemical reactions. The present review considers selective methods of organic synthesis suitable for transformation of complex functionalized molecules under mild conditions. Selected key trends in the modern organic synthesis are considered including the preparation of organofluorine compounds, catalytic cross-coupling and oxidative cross-coupling reactions, atom-economic addition reactions, methathesis processes, oxidation and reduction reactions, synthesis of heterocyclic compounds, design of new homogeneous and heterogeneous catalytic systems, application of photocatalysis, scaling up synthetic procedures to industrial level and development of new approaches to investigation of mechanisms of catalytic reactions. The bibliography includes 840 references

  13. Modern design methods of hydraulic machines according to a quality system; Moderne tecniche di progettazione delle macchine idrauliche a garanzia della qualita`

    Energy Technology Data Exchange (ETDEWEB)

    Rossi, G.; Romolotti, F.; Lazzaro, B. [Voith Riva Hydr s.p.a., Milan (Italy)

    1998-03-01

    The article underlines how the adoption of a Quality System in line with the ISO 9001 Code is an essential instrument that is necessary to safely manage the complexity of the calculation, control and organization methods connected to the unavoidable sharing out of competence relevant to design, construction and installation of modern hydraulic machines. [Italiano] L`articolo sottolinea come l`adozione di un Sistema Qualita` in linea con la norma ISO 9001, sia strumento indispensabile per la sicura gestione della maggior complessita` dei metodi di calcolo, di controllo e di organizzazione legati all`inevitabile frazionamento delle competenze relative alla progettazione, costruzione e installazione delle moderne macchine idrauliche.

  14. Modern concepts of cost accounting: A review of the ABC method specific features

    Directory of Open Access Journals (Sweden)

    Trklja Radmila

    2014-01-01

    Full Text Available New business conditions, in which the presence of turbulent changes in the environment are extremely obvious, demand, much more than before, relevant and reliable information which represent an essential support for the management in all the stages of decision making processes. In the countries with developed market and competitive economies, new approaches, philosophies, concepts and techniques in the field of expense accounting appear. The development of high technology businesses and the appearance of business globalisation raise the question of the quality of accounting information obtained using traditional methods of cost accounting and it is necessary to change the concept of establishing product costs. According to this, management accounting should ensure an informational support for managing businesses which are based on customers' demands, internal processes, continuous business improvement etc. It is only possible with the application of modern concepts of cost accounting, which will ensure efficient of cost management and business management in modern business conditions.

  15. Some considerations about literary analysis modern methods from a didactic perspective

    OpenAIRE

    Marialina Ana García Escobio; Moraima Pérez Barrera; María del Carmen Miló Anillo

    2016-01-01

    This article make it possible a close look to the modern methods of literary analysis, taking as the starting point what the teaching of literature in the joyful context should fulfill in the study of the literary play and the processes of reception and aesthetic statement, as well as the application of the aforementioned methods in the attempt to make the student arrive at rational position; But, at the same time, he/she should feel creator and coauthor of an event that should be lived from ...

  16. Assessment of modern spectral analysis methods to improve wavenumber resolution of F-K spectra

    International Nuclear Information System (INIS)

    Shirley, T.E.; Laster, S.J.; Meek, R.A.

    1987-01-01

    The improvement in wavenumber spectra obtained by using high resolution spectral estimators is examined. Three modern spectral estimators were tested, namely the Autoregressive/Maximum Entropy (AR/ME) method, the Extended Prony method, and an eigenstructure method. They were combined with the conventional Fourier method by first transforming each trace with a Fast Fourier Transform (FFT). A high resolution spectral estimator was applied to the resulting complex spatial sequence for each frequency. The collection of wavenumber spectra thus computed comprises a hybrid f-k spectrum with high wavenumber resolution and less spectral ringing. Synthetic and real data records containing 25 traces were analyzed by using the hybrid f-k method. The results show an FFT-AR/ME f-k spectrum has noticeably better wavenumber resolution and more spectral dynamic range than conventional spectra when the number of channels is small. The observed improvement suggests the hybrid technique is potentially valuable in seismic data analysis

  17. Immobilization method of yeast cells for intermittent contact mode imaging using the atomic force microscope

    International Nuclear Information System (INIS)

    De, Tathagata; Chettoor, Antony M.; Agarwal, Pranav; Salapaka, Murti V.; Nettikadan, Saju

    2010-01-01

    The atomic force microscope (AFM) is widely used for studying the surface morphology and growth of live cells. There are relatively fewer reports on the AFM imaging of yeast cells (Kasas and Ikai, 1995), (Gad and Ikai, 1995). Yeasts have thick and mechanically strong cell walls and are therefore difficult to attach to a solid substrate. In this report, a new immobilization technique for the height mode imaging of living yeast cells in solid media using AFM is presented. The proposed technique allows the cell surface to be almost completely exposed to the environment and studied using AFM. Apart from the new immobilization protocol, for the first time, height mode imaging of live yeast cell surface in intermittent contact mode is presented in this report. Stable and reproducible imaging over a 10-h time span is observed. A significant improvement in operational stability will facilitate the investigation of growth patterns and surface patterns of yeast cells.

  18. Method and apparatus for a high-resolution three dimensional confocal scanning transmission electron microscope

    Science.gov (United States)

    de Jonge, Niels [Oak Ridge, TN

    2010-08-17

    A confocal scanning transmission electron microscope which includes an electron illumination device providing an incident electron beam propagating in a direction defining a propagation axis, and a precision specimen scanning stage positioned along the propagation axis and movable in at least one direction transverse to the propagation axis. The precision specimen scanning stage is configured for positioning a specimen relative to the incident electron beam. A projector lens receives a transmitted electron beam transmitted through at least part of the specimen and focuses this transmitted beam onto an image plane, where the transmitted beam results from the specimen being illuminated by the incident electron beam. A detection system is placed approximately in the image plane.

  19. Hybrid methods for witnessing entanglement in a microscopic-macroscopic system

    International Nuclear Information System (INIS)

    Spagnolo, Nicolo; Vitelli, Chiara; Paternostro, Mauro; De Martini, Francesco; Sciarrino, Fabio

    2011-01-01

    We propose a hybrid approach to the experimental assessment of the genuine quantum features of a general system consisting of microscopic and macroscopic parts. We infer entanglement by combining dichotomic measurements on a bidimensional system and phase-space inference through the Wigner distribution associated with the macroscopic component of the state. As a benchmark, we investigate the feasibility of our proposal in a bipartite-entangled state composed of a single-photon and a multiphoton field. Our analysis shows that, under ideal conditions, maximal violation of a Clauser-Horne-Shimony-Holt-based inequality is achievable regardless of the number of photons in the macroscopic part of the state. The difficulty in observing entanglement when losses and detection inefficiency are included can be overcome by using a hybrid entanglement witness that allows efficient correction for losses in the few-photon regime.

  20. Hybrid methods for witnessing entanglement in a microscopic-macroscopic system

    Energy Technology Data Exchange (ETDEWEB)

    Spagnolo, Nicolo [Dipartimento di Fisica, Sapienza Universita di Roma, Piazzale Aldo Moro 5, I-00185 Roma (Italy); Consorzio Nazionale Interuniversitario per le Scienze Fisiche della Materia, Piazzale Aldo Moro 5, I-00185 Roma (Italy); Vitelli, Chiara [Dipartimento di Fisica, Sapienza Universita di Roma, Piazzale Aldo Moro 5, I-00185 Roma (Italy); Paternostro, Mauro [School of Mathematics and Physics, Queen' s University, BT 7 1NN Belfast (United Kingdom); De Martini, Francesco [Dipartimento di Fisica, Sapienza Universita di Roma, Piazzale Aldo Moro 5, I-00185 Roma (Italy); Accademia Nazionale dei Lincei, via della Lungara 10, I-00165 Roma (Italy); Sciarrino, Fabio [Dipartimento di Fisica, Sapienza Universita di Roma, Piazzale Aldo Moro 5, I-00185 Roma (Italy); Istituto Nazionale di Ottica, Consiglio Nazionale delle Ricerche (INO-CNR), largo E. Fermi 6, I-50125 Firenze (Italy)

    2011-09-15

    We propose a hybrid approach to the experimental assessment of the genuine quantum features of a general system consisting of microscopic and macroscopic parts. We infer entanglement by combining dichotomic measurements on a bidimensional system and phase-space inference through the Wigner distribution associated with the macroscopic component of the state. As a benchmark, we investigate the feasibility of our proposal in a bipartite-entangled state composed of a single-photon and a multiphoton field. Our analysis shows that, under ideal conditions, maximal violation of a Clauser-Horne-Shimony-Holt-based inequality is achievable regardless of the number of photons in the macroscopic part of the state. The difficulty in observing entanglement when losses and detection inefficiency are included can be overcome by using a hybrid entanglement witness that allows efficient correction for losses in the few-photon regime.

  1. Maximum Entropy Methods as the Bridge Between Microscopic and Macroscopic Theory

    Science.gov (United States)

    Taylor, Jamie M.

    2016-09-01

    This paper is concerned with an investigation into a function of macroscopic variables known as the singular potential, building on previous work by Ball and Majumdar. The singular potential is a function of the admissible statistical averages of probability distributions on a state space, defined so that it corresponds to the maximum possible entropy given known observed statistical averages, although non-classical entropy-like objective functions will also be considered. First the set of admissible moments must be established, and under the conditions presented in this work the set is open, bounded and convex allowing a description in terms of supporting hyperplanes, which provides estimates on the development of singularities for related probability distributions. Under appropriate conditions it is shown that the singular potential is strictly convex, as differentiable as the microscopic entropy, and blows up uniformly as the macroscopic variable tends to the boundary of the set of admissible moments. Applications of the singular potential are then discussed, and particular consideration will be given to certain free-energy functionals typical in mean-field theory, demonstrating an equivalence between certain microscopic and macroscopic free-energy functionals. This allows statements about L^1-local minimisers of Onsager's free energy to be obtained which cannot be given by two-sided variations, and overcomes the need to ensure local minimisers are bounded away from zero and +∞ before taking L^∞ variations. The analysis also permits the definition of a dual order parameter for which Onsager's free energy allows an explicit representation. Also, the difficulties in approximating the singular potential by everywhere defined functions, in particular by polynomial functions, are addressed, with examples demonstrating the failure of the Taylor approximation to preserve relevant shape properties of the singular potential.

  2. Obtaining the lattice energy of the anthracene crystal by modern yet affordable first-principles methods

    Science.gov (United States)

    Sancho-García, J. C.; Aragó, J.; Ortí, E.; Olivier, Y.

    2013-05-01

    The non-covalent interactions in organic molecules are known to drive their self-assembly to form molecular crystals. We compare, in the case of anthracene and against experimental (electronic-only) sublimation energy, how modern quantum-chemical methods are able to calculate this cohesive energy taking into account all the interactions between occurring dimers in both first-and second-shells. These include both O(N6)- and O(N5)-scaling methods, Local Pair Natural Orbital-parameterized Coupled-Cluster Single and Double, and Spin-Component-Scaled-Møller-Plesset perturbation theory at second-order, respectively, as well as the most modern family of conceived density functionals: double-hybrid expressions in several variants (B2-PLYP, mPW2-PLYP, PWPB95) with customized dispersion corrections (-D3 and -NL). All-in-all, it is shown that these methods behave very accurately producing errors in the 1-2 kJ/mol range with respect to the experimental value taken into account the experimental uncertainty. These methods are thus confirmed as excellent tools for studying all kinds of interactions in chemical systems.

  3. Computational methods in the pricing and risk management of modern financial derivatives

    Science.gov (United States)

    Deutsch, Hans-Peter

    1999-09-01

    In the last 20 years modern finance has developed into a complex mathematically challenging field. Very complicated risks exist in financial markets which need very advanced methods to measure and/or model them. The financial instruments invented by the market participants to trade these risk, the so called derivatives are usually even more complicated than the risks themselves and also sometimes generate new riks. Topics like random walks, stochastic differential equations, martingale measures, time series analysis, implied correlations, etc. are of common use in the field. This is why more and more people with a science background, such as physicists, mathematicians, or computer scientists, are entering the field of finance. The measurement and management of all theses risks is the key to the continuing success of banks. This talk gives insight into today's common methods of modern market risk management such as variance-covariance, historical simulation, Monte Carlo, “Greek” ratios, etc., including the statistical concepts on which they are based. Derivatives are at the same time the main reason for and the most effective means of conducting risk management. As such, they stand at the beginning and end of risk management. The valuation of derivatives and structured financial instruments is therefore the prerequisite, the condition sine qua non, for all risk management. This talk introduces some of the important valuation methods used in modern derivatives pricing such as present value, Black-Scholes, binomial trees, Monte Carlo, etc. In summary this talk highlights an area outside physics where there is a lot of interesting work to do, especially for physicists. Or as one of our consultants said: The fascinating thing about this job is that Arthur Andersen hired me not ALTHOUGH I am a physicist but BECAUSE I am a physicist.

  4. A method for automatic grain segmentation of multi-angle cross-polarized microscopic images of sandstone

    Science.gov (United States)

    Jiang, Feng; Gu, Qing; Hao, Huizhen; Li, Na; Wang, Bingqian; Hu, Xiumian

    2018-06-01

    Automatic grain segmentation of sandstone is to partition mineral grains into separate regions in the thin section, which is the first step for computer aided mineral identification and sandstone classification. The sandstone microscopic images contain a large number of mixed mineral grains where differences among adjacent grains, i.e., quartz, feldspar and lithic grains, are usually ambiguous, which make grain segmentation difficult. In this paper, we take advantage of multi-angle cross-polarized microscopic images and propose a method for grain segmentation with high accuracy. The method consists of two stages, in the first stage, we enhance the SLIC (Simple Linear Iterative Clustering) algorithm, named MSLIC, to make use of multi-angle images and segment the images as boundary adherent superpixels. In the second stage, we propose the region merging technique which combines the coarse merging and fine merging algorithms. The coarse merging merges the adjacent superpixels with less evident boundaries, and the fine merging merges the ambiguous superpixels using the spatial enhanced fuzzy clustering. Experiments are designed on 9 sets of multi-angle cross-polarized images taken from the three major types of sandstones. The results demonstrate both the effectiveness and potential of the proposed method, comparing to the available segmentation methods.

  5. Unified treatment of microscopic boundary conditions and efficient algorithms for estimating tangent operators of the homogenized behavior in the computational homogenization method

    Science.gov (United States)

    Nguyen, Van-Dung; Wu, Ling; Noels, Ludovic

    2017-03-01

    This work provides a unified treatment of arbitrary kinds of microscopic boundary conditions usually considered in the multi-scale computational homogenization method for nonlinear multi-physics problems. An efficient procedure is developed to enforce the multi-point linear constraints arising from the microscopic boundary condition either by the direct constraint elimination or by the Lagrange multiplier elimination methods. The macroscopic tangent operators are computed in an efficient way from a multiple right hand sides linear system whose left hand side matrix is the stiffness matrix of the microscopic linearized system at the converged solution. The number of vectors at the right hand side is equal to the number of the macroscopic kinematic variables used to formulate the microscopic boundary condition. As the resolution of the microscopic linearized system often follows a direct factorization procedure, the computation of the macroscopic tangent operators is then performed using this factorized matrix at a reduced computational time.

  6. Improving the speed of AFM by mechatronic design and modern control methods

    International Nuclear Information System (INIS)

    Schitter, Georg

    2009-01-01

    In Atomic Force Microscopy (AFM) high-performance and high-precision control of the AFM scanner and of the imaging forces is crucial. Particularly at high imaging speeds the dynamic behaviour of the scanner may cause imaging artifacts and limit the maximum imaging rate. This contribution discusses and presents recent improvements in AFM instrumentation for faster imaging by means of mechatronic design and utilizing modern control engineering methods. Combining these improvements enables AFM imaging at more than two orders of magnitudes faster than conventional AFMs. (orig.)

  7. Review of Polynomial Chaos-Based Methods for Uncertainty Quantification in Modern Integrated Circuits

    Directory of Open Access Journals (Sweden)

    Arun Kaintura

    2018-02-01

    Full Text Available Advances in manufacturing process technology are key ensembles for the production of integrated circuits in the sub-micrometer region. It is of paramount importance to assess the effects of tolerances in the manufacturing process on the performance of modern integrated circuits. The polynomial chaos expansion has emerged as a suitable alternative to standard Monte Carlo-based methods that are accurate, but computationally cumbersome. This paper provides an overview of the most recent developments and challenges in the application of polynomial chaos-based techniques for uncertainty quantification in integrated circuits, with particular focus on high-dimensional problems.

  8. A review of modern instrumental methods of elemental analysis of petroleum related material. Part 2

    International Nuclear Information System (INIS)

    Nadkarni, R.A.

    1991-01-01

    In this paper a review is presented of the state of the art in elemental analysis of petroleum-related materials (crude oil, gasoline, additives, and lubricants) using modern instrumental analysis techniques. The major instrumental techniques used for elemental analysis of petroleum products include atomic absorption spectrometry (both with flame and with graphite furnace atomizer), inductively coupled plasma atomic emission spectrometry, ion chromatography, microelemental methods, neutron activation, spark source mass spectrometry, and x-ray fluorescence. Each of these techniques is compared for its advantages, disadvantages, and typical applications in the petroleum field

  9. HPLC method validation for modernization of the tetracycline hydrochloride capsule USP monograph

    Directory of Open Access Journals (Sweden)

    Emad M. Hussien

    2014-12-01

    Full Text Available This paper is a continuation to our previous work aiming at development and validation of a reversed-phase HPLC for modernization of tetracycline-related USP monographs and the USP general chapter . Previous results showed that the method is accurate and precise for the assay of tetracycline hydrochloride and the limit of 4-epianhydrotetracycline impurity in the drug substance and oral suspension monographs. The aim of the current paper is to examine the feasibility of the method for modernization of USP tetracycline hydrochloride capsule monograph. Specificity, linearity, accuracy and precision were examined for tetracycline hydrochloride assay and 4-epianhydrotetracycline limit. The method was linear in the concentration range from 80% to 160% (r>0.9998 of the assay concentration (0.1 mg/mL for tetracycline hydrochloride and from 50% to 150% (r>0.997 of the acceptance criteria specified in tetracycline hydrochloride capsule monograph for 4-epianhydrotetracycline (NMT 3.0%. The recovery at three concentration levels for tetracycline hydrochloride assay was between 99% and 101% and the RSD from six preparations at the concentration 0.1 mg/mL is less than 0.6%. The recovery for 4-epianhydrotetracycline limit procedure over the concentration range from 50% to 150% is between 96% and 102% with RSD less than 5%. The results met the specified acceptance criteria.

  10. The demographic impact and development benefits of meeting demand for family planning with modern contraceptive methods.

    Science.gov (United States)

    Goodkind, Daniel; Lollock, Lisa; Choi, Yoonjoung; McDevitt, Thomas; West, Loraine

    2018-01-01

    Meeting demand for family planning can facilitate progress towards all major themes of the United Nations Sustainable Development Goals (SDGs): people, planet, prosperity, peace, and partnership. Many policymakers have embraced a benchmark goal that at least 75% of the demand for family planning in all countries be satisfied with modern contraceptive methods by the year 2030. This study examines the demographic impact (and development implications) of achieving the 75% benchmark in 13 developing countries that are expected to be the furthest from achieving that benchmark. Estimation of the demographic impact of achieving the 75% benchmark requires three steps in each country: 1) translate contraceptive prevalence assumptions (with and without intervention) into future fertility levels based on biometric models, 2) incorporate each pair of fertility assumptions into separate population projections, and 3) compare the demographic differences between the two population projections. Data are drawn from the United Nations, the US Census Bureau, and Demographic and Health Surveys. The demographic impact of meeting the 75% benchmark is examined via projected differences in fertility rates (average expected births per woman's reproductive lifetime), total population, growth rates, age structure, and youth dependency. On average, meeting the benchmark would imply a 16 percentage point increase in modern contraceptive prevalence by 2030 and a 20% decline in youth dependency, which portends a potential demographic dividend to spur economic growth. Improvements in meeting the demand for family planning with modern contraceptive methods can bring substantial benefits to developing countries. To our knowledge, this is the first study to show formally how such improvements can alter population size and age structure. Declines in youth dependency portend a demographic dividend, an added bonus to the already well-known benefits of meeting existing demands for family planning.

  11. Modern methods of cost saving of the production activity in construction

    Science.gov (United States)

    Silka, Dmitriy

    2017-10-01

    Every time economy faces recession, cost saving questions acquire increased urgency. This article shows how companies of the construction industry have switched to the new kind of economic relations over recent years. It is specified that the dominant type of economic relations does not allow to quickly reorient on the necessary tools in accordance with new requirements of economic activity. Successful experience in the new environment becomes demanded. Cost saving methods, which were proven in other industries, are offered for achievement of efficiency and competitiveness of the companies. Analysis is performed on the example of the retail sphere, which, according to the authoritative analytical reviews, is extremely innovative on both local and world economic levels. At that, methods, based on the modern unprecedentedly high opportunities of communications and informational exchange took special place among offered methods.

  12. Characterization of titanyl phthalocyanine (TiOPc) thin films by microscopic and spectroscopic method

    Science.gov (United States)

    Skonieczny, R.; Makowiecki, J.; Bursa, B.; Krzykowski, A.; Szybowicz, M.

    2018-02-01

    The titanyl phthalocyanine (TiOPc) thin film deposited on glass, silicon and gold substrate have been studied using Raman spectroscopy, atomic force microscopy (AFM), absorption and profilometry measurements. The TiOPc thin layers have been deposited at room temperature by the quasi-molecular beam evaporation technique. The Raman spectra have been recorded using micro Raman system equipped with a confocal microscope. Using surface Raman mapping techni que with polarized Raman spectra the polymorphic forms of the TiOPc thin films distribution have been obtained. The AFM height and phase image were examined in order to find surface features and morphology of the thin films. Additionally to compare experimental results, structure optimization and vibrational spectra calculation of single TiOPc molecule were performed using DFT calculations. The received results showed that the parameters like polymorphic form, grain size, roughness of the surface in TiOPc thin films can well characterize the obtained organic thin films structures in terms of their use in optoelectronics and photovoltaics devices.

  13. Comparison of visual versus microscopic methods to detect blood splatter from an intravascular catheter with engineered sharps injury protection.

    Science.gov (United States)

    Ansari, Aiysha; Ramaiah, Padmaja; Collazo, Lillian; Salihu, Hamisu M; Haiduven, Donna

    2013-11-01

    To determine whether retractable intravenous devices produced blood splatter and whether blood splatter frequency differed between visual and microscopy detection methods. In this laboratory-based experiment, 105 venipunctures were performed in a simulated brachial vein containing mock venous blood. The retraction mechanism was activated in a testing chamber with precut fabric filters, placed at 3 different locations, to capture blood splatter. Differences in filter mass, visual inspection, and microscopic analysis for presence of blood on filters were the units of analysis. Descriptive statistics, paired Student t tests, and κ statistics were used for data analysis. Blood splatter was detected visually and microscopically as follows: filter A, 70% and 71%, respectively; filter B, 12% and 9%, respectively; and filter C, 13% and 10%, respectively. A statistically significant difference was observed in the mean mass of filter A between before and after activation when confirmed by the naked eye (P = .014) and microscopically (P = .0092). Substantial agreement between methods was observed for filter A (κ - 0.78 [95% confidence interval, 0.64-0.92]), filter B (κ - 0.73 [95% confidence interval, 0.51-0.95]), and filter C (κ - 0.75 [95% confidence interval, 0.55-0.96]). However, blood was detected by microscopy and not by the naked eye in 7 instances (7%). Our findings demonstrate that splatter, which can potentially expose healthcare workers (HCWs) to bloodborne pathogens, is associated with the activation of intravascular catheters with retraction mechanisms. HCWs may not detect this splatter when it occurs and may not report a splash to mucous membranes or nonintact skin. The need to wear personal protective equipment when using such devices is reinforced.

  14. Monitoring the Error Rate of Modern Methods of Construction Based on Wood

    Science.gov (United States)

    Švajlenka, Jozef; Kozlovská, Mária

    2017-06-01

    A range of new and innovative construction systems, currently developed, represent modern methods of construction (MMC), which has the ambition to improve the performance parameters of buildings throughout their life cycle. Regarding the implementation modern methods of construction in Slovakia, assembled buildings based on wood seem to be the most preferred construction system. In the study, presented in the paper, were searched already built and lived-in wood based family houses. The residents' attitudes to such type of buildings in the context with declared designing and qualitative parameters of efficiency and sustainability are overlooked. The methodology of the research study is based on the socio-economic survey carried out during the years 2015 - 2017 within the Slovak Republic. Due to the large extent of data collected through questionnaire, only selected parts of the survey results are evaluated and discussed in the paper. This paper is aimed at evaluating the quality of buildings expressed in a view of users of existing wooden buildings. Research indicates some defects, which can be eliminated in the next production process. Research indicates, that some defects occur, so the production process quality should be improved in the future development.

  15. REVEALING OF DEFECTS OF BEARINGS WITH THE HELP OF MODERN METHODS OF CONTROL OF TECHNOLOGICAL EQUIPMENT OF HARDWARE PRODUCTION

    Directory of Open Access Journals (Sweden)

    S. M. Piskun

    2010-01-01

    Full Text Available It is shown that using of modern methods and means of technical diagnostics will allow to provide reliable accident-free exploitation of equipment, to decrease considerably labour-intensiveness, period of repair and accordingly production expenses.

  16. The Cytocam video microscope. A new method for visualising the microcirculation using Incident Dark Field technology.

    Science.gov (United States)

    Hutchings, Sam; Watts, Sarah; Kirkman, Emrys

    2016-01-01

    We report a new microcirculatory assessment device, the Braedius Cytocam, an Incident Dark Field (IDF) video microscope, and compare it with a precursor device utilising side stream dark field (SDF) imaging. Time matched measurements were made with both devices from the sublingual microcirculation of pigs subjected to traumatic injury and hemorrhagic shock at baseline and during a shock phase. Images were analysed for vessel density, microcirculatory flow and image quality. There were no differences in density or flow data recorded from the two devices at baseline [TVD IDF 14.2 ± 2.4/TVD SDF 13.2 ± 2.0, p 0.17] [MFI IDF 3 (2.8-3.0)/MFI SDF 3 (2.9-3.0), p 0.36] or during the shock state [TVD IDF 11.64 ± 3.3/TVD SDF 11.4 ± 4.0 p = 0.98] [MFI IDF 1.9 (0.6-2.7)/MFI SDF 1.7 (0.3-2.6) p 0.55]. Bland and Altman analysis showed no evidence of significant bias. Vessel contrast was significantly better with the IDF device for both capillaries [17.1 ± 3.9 (IDF) v 3.4 ± 3.6 (SDF), p = 0.0006] and venules [36.1 ± 11.4 (IDF) v 26.4 ± 7.1 (SDF) p 0.014] The Braedius Cytocam showed comparable vessel detection to a precursor device during both baseline and low flow (shock) states.

  17. Application of modern diagnostic methods to environmental improvement. Annual progress report, October 1994--September 1995

    International Nuclear Information System (INIS)

    Shepard, W.S.

    1995-12-01

    The Diagnostic Instrumentation and Analysis Laboratory (DIAL), an interdisciplinary research department in the College of Engineering at Mississippi State University (MSU), is under contract with the US Department of Energy (DOE) to develop and apply advanced diagnostic instrumentation and analysis techniques to aid in solving DOE's nuclear waste problem. The program is a comprehensive effort which includes five focus areas: advanced diagnostic systems; development/application; torch operation and test facilities; process development; on-site field measurement and analysis; technology transfer/commercialization. As part of this program, diagnostic methods will be developed and evaluated for characterization, monitoring and process control. Also, the measured parameters, will be employed to improve, optimize and control the operation of the plasma torch and the overall plasma treatment process. Moreover, on-site field measurements at various DOE facilities are carried out to aid in the rapid demonstration and implementation of modern fieldable diagnostic methods. Such efforts also provide a basis for technology transfer

  18. Application of modern diagnostic methods to environmental improvement. Annual progress report, October 1994--September 1995

    Energy Technology Data Exchange (ETDEWEB)

    Shepard, W.S.

    1995-12-01

    The Diagnostic Instrumentation and Analysis Laboratory (DIAL), an interdisciplinary research department in the College of Engineering at Mississippi State University (MSU), is under contract with the US Department of Energy (DOE) to develop and apply advanced diagnostic instrumentation and analysis techniques to aid in solving DOE`s nuclear waste problem. The program is a comprehensive effort which includes five focus areas: advanced diagnostic systems; development/application; torch operation and test facilities; process development; on-site field measurement and analysis; technology transfer/commercialization. As part of this program, diagnostic methods will be developed and evaluated for characterization, monitoring and process control. Also, the measured parameters, will be employed to improve, optimize and control the operation of the plasma torch and the overall plasma treatment process. Moreover, on-site field measurements at various DOE facilities are carried out to aid in the rapid demonstration and implementation of modern fieldable diagnostic methods. Such efforts also provide a basis for technology transfer.

  19. Some considerations about literary analysis modern methods from a didactic perspective

    Directory of Open Access Journals (Sweden)

    Marialina Ana García Escobio

    2016-12-01

    Full Text Available This article make it possible a close look to the modern methods of literary analysis, taking as the starting point what the teaching of literature in the joyful context should fulfill in the study of the literary play and the processes of reception and aesthetic statement, as well as the application of the aforementioned methods in the attempt to make the student arrive at rational position; But, at the same time, he/she should feel creator and coauthor of an event that should be lived from a type of special reading done; Herein the importance of a system of methodological work that prepares the professors to contribute from each of the classes to the development of skills for the students´ literary analysis.

  20. Microwave Microscope

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Makes ultra-high-resolution field measurements. The Microwave Microscope (MWM) has been used in support of several NRL experimental programs involving sea...

  1. THE MODERN TRENDS AND EXPERIMENTAL METHODS OF TRAINING FUTURE SPECIALISTS IN THE FIELD OF HISTRIONIC ART

    Directory of Open Access Journals (Sweden)

    Julia Sergeevna Skvortsova

    2013-11-01

    Full Text Available This article reflects the specific ways of training specialists in the sphere of histrionic art, contemporary trends and special scientific experiments in the education of actors.We consider the traditional aspects of histrionic art specialists’ occupational fitness and modern requirements upon actor’s psycho-physical training.There also follows historical parallels in studying actor’s energy in the researches of K. Stanislavsky, M. Chekhov, T. Reebo, W. James, A. Maneggetty as well as in the modern researches of L. Gracheva.And there was proved the reason for including some Yoga elements and Academician M.Norbecov’s exercises system into the actors training practice.In the article Yoga for actors considers as a system of emotional and physical preparation to the artistic creative work, as a method of self-control that let an actor be really deep in his creative condition.There also was described an advantageous result of applying at our experimental laboratory of actors Yoga classes some exercises that reveal connection of person’s carriage and his condition in the process of working on the outward demonstration of this or that emotion in order to create appropriate inner state.Object: Studying the influence on the productivity of actors’ professional education of the Yoga elements included into the actors’ psycho-technique practice training.Methods: theoretical, experimental and observational methods of research.Results: After using these methods during the classes the rate of student’s psycho-physical APPARATUS has extremely increased.The area of application: the educational process at artistic creative high schools.DOI: http://dx.doi.org/10.12731/2218-7405-2013-7-52

  2. Advanced microscopic methods for the detection of adhesion barriers in immunology in medical imaging

    Science.gov (United States)

    Lawrence, Shane

    2017-07-01

    Advanced methods of microscopy and advanced techniques of analysis stemming therefrom have developed greatly in the past few years.The use of single discrete methods has given way to the combination of methods which means an increase in data for processing to progress to the analysis and diagnosis of ailments and diseases which can be viewed by each and any method.This presentation shows the combination of such methods and gives example of the data which arises from each individual method and the combined methodology and suggests how such data can be streamlined to enable conclusions to be drawn about the particular biological and biochemical considerations that arise.In this particular project the subject of the methodology was human lactoferrin and the relation of the adhesion properties of hlf in the overcoming of barriers to adhesion mainly on the perimeter of the cellular unit and how this affects the process of immunity in any particular case.

  3. Microscopic description of nuclear few-body systems with the stochastic variational method

    International Nuclear Information System (INIS)

    Suzuki, Yasuyuki

    2000-01-01

    A simple gambling procedure called the stochastic variational method can be applied, together with appropriate variational trial functions, to solve a few-body system where the correlation between the constituents plays an important role in determining its structure. The usefulness of the method is tested by comparing to other accurate solutions for Coulombic systems. Examples of application shown here include few-nucleon systems interacting with realistic forces and few-cluster systems with the Pauli principle being taken into account properly. These examples confirm the power of the stochastic variational method. There still remain many problems for extending to a system consisting of more particles. (author)

  4. A stochastic immersed boundary method for fluid-structure dynamics at microscopic length scales

    International Nuclear Information System (INIS)

    Atzberger, Paul J.; Kramer, Peter R.; Peskin, Charles S.

    2007-01-01

    In modeling many biological systems, it is important to take into account flexible structures which interact with a fluid. At the length scale of cells and cell organelles, thermal fluctuations of the aqueous environment become significant. In this work, it is shown how the immersed boundary method of [C.S. Peskin, The immersed boundary method, Acta Num. 11 (2002) 1-39.] for modeling flexible structures immersed in a fluid can be extended to include thermal fluctuations. A stochastic numerical method is proposed which deals with stiffness in the system of equations by handling systematically the statistical contributions of the fastest dynamics of the fluid and immersed structures over long time steps. An important feature of the numerical method is that time steps can be taken in which the degrees of freedom of the fluid are completely underresolved, partially resolved, or fully resolved while retaining a good level of accuracy. Error estimates in each of these regimes are given for the method. A number of theoretical and numerical checks are furthermore performed to assess its physical fidelity. For a conservative force, the method is found to simulate particles with the correct Boltzmann equilibrium statistics. It is shown in three dimensions that the diffusion of immersed particles simulated with the method has the correct scaling in the physical parameters. The method is also shown to reproduce a well-known hydrodynamic effect of a Brownian particle in which the velocity autocorrelation function exhibits an algebraic (τ -3/2 ) decay for long times [B.J. Alder, T.E. Wainwright, Decay of the Velocity Autocorrelation Function, Phys. Rev. A 1(1) (1970) 18-21]. A few preliminary results are presented for more complex systems which demonstrate some potential application areas of the method. Specifically, we present simulations of osmotic effects of molecular dimers, worm-like chain polymer knots, and a basic model of a molecular motor immersed in fluid subject to a

  5. The modern methods of treatment of patients with radiation syndrome in a specialized hospital (analytical review)

    International Nuclear Information System (INIS)

    Selidovkin, G.D.

    1995-01-01

    Modern methods of treatment of patients with various symptoms of acute radiation disease in a specialized hospital are reviewed. The treatment starts from prophylactic prescription of antibacterial antibiotics of latest generations (imipinem, cephalosporin of 3-rd generation), antifungal and antiviral remedies, immunoglobulin G, selective decontamination of intestines should be carried out. Transfusion of donor thrombocytes and erythrocytes in the quantities adequate to the degree of explicit cytopenia should be provided. Full parenteral feeding should be prescribed, desintoxication and adjustment therapy is be administered. Transplantation of HLA-identical bone marrow may be recommended only over the range from 10 to 15 Gy close to uniform irradiation. The most promising in the therapy of acute radiation disease - 3, 4 are hemopoietic growth factors. 76 refs.; 2 tabs

  6. MODERN INSTRUMENTAL METHODS TO CONTROL THE SEED QUALITY IN ROOT VEGETABLES

    Directory of Open Access Journals (Sweden)

    F. B. Musaev

    2017-01-01

    Full Text Available The standard methods of analysis don’t meet all modern requirements to determine the seed a quality. These methods can’t unveil inner deficiencies that are very important to control seed viability. The capabilities of new instrumental method to analyze the seed quality of root vegetables were regarded in the article. The method of micro-focus radiography is distinguished from other existing methods by more sensitivity, rapidity and easiness to be performed. Based on practical importance the visualization of inner seed structure, it allows determining far before seed germination the degree of endosperm development and embryo; the presence of inner damages and infections, occupation and damage caused by pests. The use of micro-focus radiography enables to detect the degree of seed quality difference for some traits such as monogermity and self-fertilization that are economically valuable for breeding program in red beet. With the aid of the method the level of seed development, damage and inner deficiencies in carrot and parsnip can be revealed. In X-ray projection seeds of inbred lines of radish significantly differed from variety population ones for their underdevelopment in the inner structure. The advantage of the method is that seeds rest undamaged after quality analyzing and both can be used for further examination with the use of other methods or be sown; that is quite important for breeders, when handling with small quantity or collectable plant breeding material. The results radiography analyses can be saved and archived that enables to watch for seed qualities in dynamic; this data can be also used at possible arbitration cases. 

  7. Modern Cored Wire Injection 2PE-9 Method in the Production of Ductile Iron

    Directory of Open Access Journals (Sweden)

    E. Guzik

    2012-04-01

    Full Text Available The results of studies on the use of modern two cored wires injection method for production of nodular graphite cast iron with use of unique implementation of drum ladle as a treatment/ transport and casting ladle instead vertical treatment ladle was described. The injection of length of Ø 9mm wires, cored: in FeSi + Mg nodulariser mixture and inoculant master alloy is a treatment method which can be used to produce iron melted in coreless induction furnace. This paper describes the results of using this method for possibility production of ductile iron under specific industrial conditions. In this case was taken ductile iron with material designation: EN-GJS-450- 10 Grade according PN-EN 1563:2000. Microstructure of 28 trials was controlled on internally used sample which has been correlated with standard sample before. The paper presents typical metallic matrix and graphite characteristic. Additionally, mechanical properties were checked in one experiment. Because of further possibility treatment temperature reduction only the rough magnesium recovery and cost of this new method are given.

  8. Microscopic and self-consistent description of nuclear properties by extended generator-coordinate method

    International Nuclear Information System (INIS)

    Didong, M.

    1976-01-01

    The extend generator-coordinated method is discussed and a procedure is given for the solution of the Hill-Wheeler equation. The HFB-theory, the particle-number and angular-momentum projections necessary for symmetry, and the modified surprice delta interaction are discussed. The described procedures are used to calculate 72 Ge, 70 Zn and 74 Ge properties. (BJ) [de

  9. Implicit methods for equation-free analysis: convergence results and analysis of emergent waves in microscopic traffic models

    DEFF Research Database (Denmark)

    Marschler, Christian; Sieber, Jan; Berkemer, Rainer

    2014-01-01

    We introduce a general formulation for an implicit equation-free method in the setting of slow-fast systems. First, we give a rigorous convergence result for equation-free analysis showing that the implicitly defined coarse-level time stepper converges to the true dynamics on the slow manifold...... against the direction of traffic. Equation-free analysis enables us to investigate the behavior of the microscopic traffic model on a macroscopic level. The standard deviation of cars' headways is chosen as the macroscopic measure of the underlying dynamics such that traveling wave solutions correspond...... to equilibria on the macroscopic level in the equation-free setup. The collapse of the traffic jam to the free flow then corresponds to a saddle-node bifurcation of this macroscopic equilibrium. We continue this bifurcation in two parameters using equation-free analysis....

  10. Investigation into macroscopic and microscopic behaviors of wet granular soils using discrete element method and X-ray computed tomography

    Science.gov (United States)

    Than, Vinh-Du; Tang, Anh-Minh; Roux, Jean-Noël; Pereira, Jean-Michel; Aimedieu, Patrick; Bornert, Michel

    2017-06-01

    We present an investigation into macroscopic and microscopic behaviors of wet granular soils using the discrete element method (DEM) and the X-ray Computed Tomography (XRCT) observations. The specimens are first prepared in very loose states, with frictional spherical grains in the presence of a small amount of an interstitial liquid. Experimental oedometric tests are carried out with small glass beads, while DEM simulations implement a model of spherical grains joined by menisci. Both in experiments and in simulations, loose configurations with solid fraction as low as 0.30 are prepared under low stress, and undergo a gradual collapse in compression, until the solid fraction of cohesionless bead packs (0.58 to 0.6) is obtained. In the XRCT tests, four 3D tomography images corresponding to different typical stages of the compression curve are used to characterize the microstructure.

  11. Adaptive striping watershed segmentation method for processing microscopic images of overlapping irregular-shaped and multicentre particles.

    Science.gov (United States)

    Xiao, X; Bai, B; Xu, N; Wu, K

    2015-04-01

    Oversegmentation is a major drawback of the morphological watershed algorithm. Here, we study and reveal that the oversegmentation is not only because of the irregular shapes of the particle images, which people are familiar with, but also because of some particles, such as ellipses, with more than one centre. A new parameter, the striping level, is introduced and the criterion for striping parameter is built to help find the right markers prior to segmentation. An adaptive striping watershed algorithm is established by applying a procedure, called the marker searching algorithm, to find the markers, which can effectively suppress the oversegmentation. The effectiveness of the proposed method is validated by analysing some typical particle images including the images of gold nanorod ensembles. © 2014 The Authors Journal of Microscopy © 2014 Royal Microscopical Society.

  12. Comparison and Supervised Learning of Segmentation Methods Dedicated to Specular Microscope Images of Corneal Endothelium

    Directory of Open Access Journals (Sweden)

    Yann Gavet

    2014-01-01

    Full Text Available The cornea is the front of the eye. Its inner cell layer, called the endothelium, is important because it is closely related to the light transparency of the cornea. An in vivo observation of this layer is performed by using specular microscopy to evaluate the health of the cells: a high spatial density will result in a good transparency. Thus, the main criterion required by ophthalmologists is the cell density of the cornea endothelium, mainly obtained by an image segmentation process. Different methods can perform the image segmentation of these cells, and the three most performing methods are studied here. The question for the ophthalmologists is how to choose the best algorithm and to obtain the best possible results with it. This paper presents a methodology to compare these algorithms together. Moreover, by the way of geometric dissimilarity criteria, the algorithms are tuned up, and the best parameter values are thus proposed to the expert ophthalmologists.

  13. An automatic evaluation method for the surface profile of a microlens array using an optical interferometric microscope

    International Nuclear Information System (INIS)

    Lin, Chern-Sheng; Loh, Guo-Hao; Fu, Shu-Hsien; Chang, Hsun-Kai; Yang, Shih-Wei; Yeh, Mau-Shiun

    2010-01-01

    In this paper, an automatic evaluation method for the surface profile of a microlens array using an optical interferometric microscope is presented. For inspecting the microlens array, an XY-table is used to position it. With a He–Ne laser beam and optical fiber as a probing light, the measured image is sent to the computer to analyze the surface profile. By binary image slicing and area recognition, this study located the center of each ring and determined the substrate of the microlens array image through the background of the entire microlens array interference image. The maximum and minimum values of every segment brightness curve were determined corresponding to the change in the segment phase angle from 0° to 180°. According to the ratio of the actual ring area and the ideal ring area, the area ratio method was adopted to find the phase-angle variation of the interference ring. Based on the ratio of actual ring brightness and the ideal ring brightness, the brightness ratio method was used to determine the phase-angle variation of the interference ring fringe. The area ratio method and brightness ratio method are interchangeable in precisely determining the phase angles of the innermost and outermost rings of the interference fringe and obtaining different microlens surface altitudes of respective pixels in the segment, to greatly increase the microlens array surface profile inspection accuracy and quality

  14. New method for studying the microscopic foundations of the interacting boson model

    International Nuclear Information System (INIS)

    Klein, A.; Vallieres, M.

    1981-01-01

    We describe (i) a mapping, using a multishell seniority basis, from a prescribed subspace of a shell model space to an associated boson space. (ii) A new dynamical procedure for selecting the collective variables within the boson space, based on the invariance of the trace. (iii) A comparison with exact calculations for a multi-level pairing model, to demonstrate that the method works. (orig.)

  15. Microscopic deformation and strain hardening analysis of ferrite–bainite dual-phase steels using micro-grid method

    International Nuclear Information System (INIS)

    Ishikawa, Nobuyuki; Yasuda, Kyono; Sueyoshi, Hitoshi; Endo, Shigeru; Ikeda, Hiroshi; Morikawa, Tatsuya; Higashida, Kenji

    2015-01-01

    The local strain measurement method using nanometer-scaled micro grids printed on the surface of a specimen by an electron lithography technique (the micro-grid method) has been established. Microscopic deformation behavior of the ferrite–bainite steels with different bainite volume fraction, 16% and 40% of bainite, was evaluated. Strain localization in the ferrite phase adjacent to the ferrite/bainite boundary was clearly observed and visualized. Highly strained regions expanded toward the inner region of the ferrite phase and connected each other with an increase of macroscopic strain. The existence of hard bainite phase plays an important role for inducing strain localization in the ferrite phase by plastic constraint in the boundary parallel to the tensile direction. In order to obtain further understanding of microscopic deformation behavior, finite element analysis using the representative volume element, which is expressed by the axisymmetric unit cell containing a hard phase surrounded by a soft phase matrix, was conducted. It was found that the macroscopic stress–strain behavior of ferrite–bainite steels was well simulated by the unit cell models. Strain concentration in the ferrite phase was highly enhanced for the ferrite-40% bainite steel, and this imposed higher internal stress in the bainite phase, resulting in higher strain hardening rate in the early stage of the deformation. However, smaller ferrite volume fraction of ferrite-40% bainite steel induced bainite plastic deformation in order to fulfill the macroscopic strain of the steel. Accordingly, strain hardening capacity of the ferrite-40% bainite steel was reduced to a significant degree, resulting in a smaller uniform elongation than the ferrite-16% bainite steel

  16. Study of five-dimensional potential-energy surfaces for actinide isotopes by the macroscopic-microscopic method

    Science.gov (United States)

    Fan, T. S.; Wang, Z. M.; Zhu, X.; Zhu, W. J.; Zhong, C. L.

    2017-09-01

    In this work, the nuclear potential-energy of the deformed nuclei as a function of shape coordinates is calculated in a five-dimensional (5D) parameter space of the axially symmetric generalized Lawrence shapes, on the basis of the macroscopic-microscopic method. The liquid-drop part of the nuclear energy is calculated according to the Myers-Swiatecki model and the Lublin-Strasbourg-drop (LSD) formula. The Woods-Saxon and the folded-Yukawa potentials for deformed nuclei are used for the shell and pairing corrections of the Strutinsky-type. The pairing corrections are calculated at zero temperature, T, related to the excitation energy. The eigenvalues of Hamiltonians for protons and neutrons are found by expanding the eigen-functions in terms of harmonic-oscillator wave functions of a spheroid. Then the BCS pair is applied on the smeared-out single-particle spectrum. By comparing the results obtained by different models, the most favorable combination of the macroscopic-microscopic model is known as the LSD formula with the folded-Yukawa potential. Potential-energy landscapes for actinide isotopes are investigated based on a grid of more than 4,000,000 deformation points and the heights of static fission barriers are obtained in terms of a double-humped structure on the full 5D parameter space. In order to locate the ground state shapes, saddle points, scission points and optimal fission path on the calculated 5D potential-energy surface, the falling rain algorithm and immersion method are designed and implemented. The comparison of our results with available experimental data and others' theoretical results confirms the reliability of our calculations.

  17. Microscopic Theory of Fission

    International Nuclear Information System (INIS)

    Younes, W; Gogny, D

    2008-01-01

    In recent years, the microscopic method has been applied to the notoriously difficult problem of nuclear fission with unprecedented success. In this paper, we discuss some of the achievements and promise of the microscopic method, as embodied in the Hartree-Fock method using the Gogny finite-range effective interaction, and beyond-mean-field extensions to the theory. The nascent program to describe induced fission observables using this approach at the Lawrence Livermore National Laboratory is presented

  18. Modern Methods of Multidimensional Data Visualization: Analysis, Classification, Implementation, and Applications in Technical Systems

    Directory of Open Access Journals (Sweden)

    I. K. Romanova

    2016-01-01

    Full Text Available The article deals with theoretical and practical aspects of solving the problem of visualization of multidimensional data as an effective means of multivariate analysis of systems. Several classifications are proposed for visualization techniques, according to data types, visualization objects, the method of transformation of coordinates and data. To represent classification are used charts with links to the relevant work. The article also proposes two classifications of modern trends in display technology, including integration of visualization techniques as one of the modern trends of development, along with the introduction of interactive technologies and the dynamics of development processes. It describes some approaches to the visualization problem, which are concerned with fulfilling the needs. The needs are generated by the relevant tasks such as information retrieval in global networks, development of bioinformatics, study and control of business processes, development of regions, etc. The article highlights modern visualization tools, which are capable of improving the efficiency of the multivariate analysis and searching for solutions in multi-objective optimization of technical systems, but are not very actively used for such studies. These are horizontal graphs, graphics "quantile-quantile", etc. The paper proposes to use Choropleth cards traditionally used in cartography for simultaneous presentation of the distribution parameters of several criteria in the space. It notes that visualizations of graphs in network applications can be more actively used to describe the control system. The article suggests using the heat maps to provide graphical representation of the sensitivity of the system quality criteria under variations of options (multivariate analysis of technical systems. It also mentions that it is useful to extend the supervising heat maps to the task of estimating quality of identify in constructing system models. A

  19. [A brief history of resuscitation - the influence of previous experience on modern techniques and methods].

    Science.gov (United States)

    Kucmin, Tomasz; Płowaś-Goral, Małgorzata; Nogalski, Adam

    2015-02-01

    Cardiopulmonary resuscitation (CPR) is relatively novel branch of medical science, however first descriptions of mouth-to-mouth ventilation are to be found in the Bible and literature is full of descriptions of different resuscitation methods - from flagellation and ventilation with bellows through hanging the victims upside down and compressing the chest in order to stimulate ventilation to rectal fumigation with tobacco smoke. The modern history of CPR starts with Kouwenhoven et al. who in 1960 published a paper regarding heart massage through chest compressions. Shortly after that in 1961Peter Safar presented a paradigm promoting opening the airway, performing rescue breaths and chest compressions. First CPR guidelines were published in 1966. Since that time guidelines were modified and improved numerously by two leading world expert organizations ERC (European Resuscitation Council) and AHA (American Heart Association) and published in a new version every 5 years. Currently 2010 guidelines should be obliged. In this paper authors made an attempt to present history of development of resuscitation techniques and methods and assess the influence of previous lifesaving methods on nowadays technologies, equipment and guidelines which allow to help those women and men whose life is in danger due to sudden cardiac arrest. © 2015 MEDPRESS.

  20. Modern methods of high-pressure fuel pump common rail power system diagnostics

    Directory of Open Access Journals (Sweden)

    Kyshchun В.

    2016-08-01

    Full Text Available We've considered high pressure fuel pumps design features and equipment for their diagnosis. It was noted that the reliability of the fuel elements Common Rail system primarily provide precision parts of the fuel equipment. As a consequence, the aim of study was comparative analysis and laborious of modern methods of the high pressure fuel pump diagnosing. In particular, the definition of a technical condition of the fuel pump was carried out using a special stand and by measuring the fuel pressure and duty cycle of the pressure regulator signal. As an object of our research we've chosen Bosch № 0445010008 fuel pump (from Mercedes Benz E320cdi in which the plunger pairs were changed alternately with different technical conditions. Preliminary fuel pump parameters were determined by hydraulic testing. Based on conducted experiments we've found out that fuel pressure measurement change method and the duty cycle of the pressure regulator signal at the starting and full load modes less laborious compared to the definition of a technical condition of the pump on the stand. The results of both methods of diagnosing confirmed identity of the fuel pumps.

  1. Use of modern methods of fibre surface modification to obtain the multifunctional properties of textile materials

    Directory of Open Access Journals (Sweden)

    Jocić Dragan

    2003-01-01

    Full Text Available The modern textile fibre treatments aim to obtain the required level of beneficial effect while attempting to confine the modification to the fibre surface. Recently, much attention has been focused on different physical methods of fibre surface modification, cold plasma treatment being considered as very useful. Moreover, there are efficient chemical methods available, such as peroxide, biopolymer and enzyme treatment. Some interesting combinations of these physical and chemical surface modification methods as means to modify fibre surface topography and thus controlling the surface-related properties of the fibre are presented in this paper. The properties obtained are discussed on the basis of the physico-chemical changes in the surface layer of the fibre, being assessed by wettability and contact angle measurements, as well as by FTIR-ATR and XPS analysis. The SEM and AFM technique are used to assess the changes in the fibre surface topography and to correlate these changes to the effectiveness, uniformity and severity of the textile fibre surface modification treatments.

  2. A novel microscopic method for analyzing Gram-stained vaginal smears in the diagnosis of disorders of vaginal microflora.

    Science.gov (United States)

    Nenadić, Dane B; Pavlović, Miloš D; Motrenko, Tatjana

    2015-08-01

    The Nugent's score is still the gold standard in the great majority of studies dealing with the assessment of vaginal flora and the diagnosis of bacterial vaginosis (BV). The aim of this study was to show that the analysis of Gram-stained vaginal samples under microscope at the magnification of x200 (a novel microscopic method--NMM), as a fast and simple tool, easily applicable in everyday practice, better reflects complexity of vaginal microflora than the Nugent's methodology (x1000). Gram-stained vaginal smears from 394 asymptomatic pregnant women (24-28 week of pregnancy) were classified according to the Nugent's microscopic criteria (immersion, magnification x1000). The smears were then reexamined under immersion but at magnification x200. All samples were classified into 6 groups according to semiquanititative assessment of numbers (cellularity) and the ratio of rod (length < 1.5 microm) and small bacterial (< 1.5 microm) forms: hypercellular (normal full--NF), moderately cellular (normal mid-NM), hypocellular (normal empty--NE), bacterial vaginosis full (BVF), bacterial vaginosis mid (BVM), and bacterial vaginosis empty (BVE). Also yeasts, coccae, bifido and lepto bacterial forms as well polymorphonuclear (PMN) leukocytes were identified. According to the Nugent's scoring, BV was found in 78, intermediate findings in 63, and yeasts in 48 patients. By our criteria BV was confirmed in 88 patients (37 BVF, 24 BVM, and 27 BVN). Generally, both tools proved to be highly concordant for the diagnosis of BV (Lin's concordance correlation coefficient = 0.9852). In 40% of the women mixed flora was found: yeasts in 126 (32%), coccae in 145 (37%), bifido forms in 32 (8%) and lepto forms in 20 (5%). Almost a half of BV patients had also yeasts (39/88). Elevated PMN numbers were found in 102 (33%) patients with normal and in 36 (41%) women with BV. The newly described methodology is simpler to apply and much better reflects diversity of vaginal microflora. In this way it

  3. Microscopic Polyangiitis

    Science.gov (United States)

    ... body, specifically the feet, lower legs and, in bed-ridden patients, the buttocks. The skin findings of cutaneous ... that are in contact with the lungs’ microscopic air sacs – the condition may quickly pose a threat ...

  4. Investigation of modern methods of probalistic sensitivity analysis of final repository performance assessment models (MOSEL)

    International Nuclear Information System (INIS)

    Spiessl, Sabine; Becker, Dirk-Alexander

    2017-06-01

    Sensitivity analysis is a mathematical means for analysing the sensitivities of a computational model to variations of its input parameters. Thus, it is a tool for managing parameter uncertainties. It is often performed probabilistically as global sensitivity analysis, running the model a large number of times with different parameter value combinations. Going along with the increase of computer capabilities, global sensitivity analysis has been a field of mathematical research for some decades. In the field of final repository modelling, probabilistic analysis is regarded a key element of a modern safety case. An appropriate uncertainty and sensitivity analysis can help identify parameters that need further dedicated research to reduce the overall uncertainty, generally leads to better system understanding and can thus contribute to building confidence in the models. The purpose of the project described here was to systematically investigate different numerical and graphical techniques of sensitivity analysis with typical repository models, which produce a distinctly right-skewed and tailed output distribution and can exhibit a highly nonlinear, non-monotonic or even non-continuous behaviour. For the investigations presented here, three test models were defined that describe generic, but typical repository systems. A number of numerical and graphical sensitivity analysis methods were selected for investigation and, in part, modified or adapted. Different sampling methods were applied to produce various parameter samples of different sizes and many individual runs with the test models were performed. The results were evaluated with the different methods of sensitivity analysis. On this basis the methods were compared and assessed. This report gives an overview of the background and the applied methods. The results obtained for three typical test models are presented and explained; conclusions in view of practical applications are drawn. At the end, a recommendation

  5. Investigation of modern methods of probalistic sensitivity analysis of final repository performance assessment models (MOSEL)

    Energy Technology Data Exchange (ETDEWEB)

    Spiessl, Sabine; Becker, Dirk-Alexander

    2017-06-15

    Sensitivity analysis is a mathematical means for analysing the sensitivities of a computational model to variations of its input parameters. Thus, it is a tool for managing parameter uncertainties. It is often performed probabilistically as global sensitivity analysis, running the model a large number of times with different parameter value combinations. Going along with the increase of computer capabilities, global sensitivity analysis has been a field of mathematical research for some decades. In the field of final repository modelling, probabilistic analysis is regarded a key element of a modern safety case. An appropriate uncertainty and sensitivity analysis can help identify parameters that need further dedicated research to reduce the overall uncertainty, generally leads to better system understanding and can thus contribute to building confidence in the models. The purpose of the project described here was to systematically investigate different numerical and graphical techniques of sensitivity analysis with typical repository models, which produce a distinctly right-skewed and tailed output distribution and can exhibit a highly nonlinear, non-monotonic or even non-continuous behaviour. For the investigations presented here, three test models were defined that describe generic, but typical repository systems. A number of numerical and graphical sensitivity analysis methods were selected for investigation and, in part, modified or adapted. Different sampling methods were applied to produce various parameter samples of different sizes and many individual runs with the test models were performed. The results were evaluated with the different methods of sensitivity analysis. On this basis the methods were compared and assessed. This report gives an overview of the background and the applied methods. The results obtained for three typical test models are presented and explained; conclusions in view of practical applications are drawn. At the end, a recommendation

  6. Teaching issues of contemporary history using historical sources and modern teaching methods

    Directory of Open Access Journals (Sweden)

    Gruber Gabriela

    2017-01-01

    Full Text Available The study of history is becoming increasingly less interesting to students, despite the fact that the history teaching process has been continuously modernized during recent years. It is an observation which can be perceived even if we don`t make an elaborated research in the field. Some empirical data show us that students in secondary and High Schools are less interested in studying History than in studying Geography or other social sciences. The number of students who are determined to study History in universities has significantly dropped in recent years [1]. Of course, there are multiple causes and the factors behind this change are numerous and varied. In this paper we handle only some changes in teaching History in High Schools, as they are designed in History Curricula and in History textbooks. Therefore during the first sequence of this paper we shall analyze the History Curricula for High School, 11th and 12th grades, regarding their finalities (competencies, some relevant contents and the recommended pedagogical approaches about the teaching methods and the auxiliary material. In the second part of the paper we propose some teaching activities through which students would practice the specific competencies from their Curriculum for History. We aim at presenting attractive teaching material and learning methods and applying the methodological recommendations from the High school Curricula for History, 11th and 12th grades.

  7. Modernized accurate methods for processing of in-core measurement signals in WWER reactors

    International Nuclear Information System (INIS)

    Polak, T.

    1996-01-01

    Utilization of the new accurate WIMS-KAERI library (WIMKAL-88) to generate the following characteristics for Rhodium SPND: Sensitivity depletion law by high (approx= 75%) burnup of emitter; influence of burnup-history on depletion law course; influence of neutron spectrum change on Rh-SPND sensitivity caused by change of fuel enrichment, fuel burnup, moderator temperature, concentration of boracid, central pin power rate and concentration of Xe 135 ; generating and experimental testing of Rh-SPND signal to linear pin power rate and signal to neutron flux conversion factors. Rh-SPND instrumentation optimization (reduction) related to safety and operational aspects as needed for 3D power surveillance in WWER-1000 reactors. Analysis of SPND reduction from 64x7 to 46x7 by method of Shannon information entropy optimization. Influence of reduction on accuracy of 3D power distribution reconstruction. Physical methods of 3D power distribution unfolding in new modernized on-line I and C system in NPP J. Bohunice with in-core measurements according to 210 thermocouples and 36x7 Rh-SPNDs. Program system TOPRE under QNX operating system network in FORTRAN 77, neutronic background calculations by macrocode MOBY-DICK. (author). 10 refs, 6 figs, 7 tabs

  8. Analysis of individual environmental particles using modern methods of electron microscopy and X-ray microanalysis

    International Nuclear Information System (INIS)

    Laskin, A.; Cowin, J.P.; Iedema, M.J.

    2006-01-01

    Understanding the composition of particles in the atmosphere is critical because of their health effects and their direct and indirect effects on radiative forcing, and hence on climate. In this manuscript, we demonstrate the utility of single particle off-line analysis to investigate the chemistry of individual atmospheric particles using modern, state-of-the-art electron microscopy and time-of-flight secondary ionization mass spectrometry techniques. We show that these methods provide specific, detailed data on particle composition, chemistry, morphology, phase and internal structure. This information is crucial for evaluating hygroscopic properties of aerosols, understanding aerosol aging and reactivity, and correlating the characteristics of aerosols with their optical properties. The manuscript presents a number of analytical advances in methods of electron probe particle analysis along with a brief review of a number of the research projects carried out in the authors' laboratory on the chemical characterization of environmental particles. The obtained data offers a rich set of qualitative and quantitative information on the particle chemistry, composition and the mechanisms of gas-particle interactions which are of high importance to atmospheric processes involving particulate matter and air pollution

  9. Modern Evaluation of Liquisolid Systems with Varying Amounts of Liquid Phase Prepared Using Two Different Methods

    Directory of Open Access Journals (Sweden)

    Barbora Vraníková

    2015-01-01

    Full Text Available Liquisolid systems are an innovative dosage form used for enhancing dissolution rate and improving in vivo bioavailability of poorly soluble drugs. These formulations require specific evaluation methods for their quality assurance (e.g., evaluation of angle of slide, contact angle, or water absorption ratio. The presented study is focused on the preparation, modern in vitro testing, and evaluation of differences of liquisolid systems containing varying amounts of a drug in liquid state (polyethylene glycol 400 solution of rosuvastatin in relation to an aluminometasilicate carrier (Neusilin US2. Liquisolid powders used for the formulation of final tablets were prepared using two different methods: simple blending and spraying of drug solution onto a carrier in fluid bed equipment. The obtained results imply that the amount of liquid phase in relation to carrier material had an effect on the hardness, friability, and disintegration of tablets, as well as their height. The use of spraying technique enhanced flow properties of the prepared mixtures, increased hardness values, decreased friability, and improved homogeneity of the final dosage form.

  10. Antisperm antibodies as a factor of male infertility. Relevance, modern methods of diagnosis and treatment

    Directory of Open Access Journals (Sweden)

    O. A. Nikiforov

    2017-08-01

    Full Text Available According to WHO statistics 40 % of childless marriage is due to factors of male infertility. One of them is the presence of antisperm antibodies in the male organism, which may be in blood serum, on the surface of spermatozoids and seminal plasma. Aim. Оn the grounds of specialized literature analysis, to show the relevance of this problem in Reproductive Medicine, to descript Basic methods of Modern treatment and diagnosis of this pathology in the body of infertile males. The most common methods of antisperm antibodies identifying are: MAR-test sample Shuvarskiy–Sims–Hyuner, Kurtsrok–Miller test, the method of latex agglutination, solid-phase immunoenzymatic blood test. Indications for antisperm antibodies determining are: modified indices, deviations in post-coital test, a negative test of sperm and cervical mucus interaction in vitro, unexplained infertility in the married couples, failure or low indices during IVF (in vitro fertilization and of course, the exclusion of other causes of infertility. When antisperm antibodies are detected, the strategy of treatment may be destined to reduction of their titer for further pregnancy. Such types of therapy can be used: contraceptive (long-term use contraception barrier to reduce antisperm antibodies titer in women, plasmapheresis, artificial insemination with pretreated from antisperm antibodies husband's sperm, methods of assisted reproductive technologies. Conclusoins. The formation of antisperm antibodies leads to infertility of immunological genesis (in 20 % of couples with unexplained infertility. To confirm their presence in the male body it is necessary to perform the MAR-test, Shuvarsky test, other tests and, of course, the exclusion of other causes of infertility. Men of reproductive age with an immunological factor of infertility provides for a comprehensive treatment, including elimination of all possible causative and contributing factors of infertility (infection of the male

  11. Comparison and analysis of two modern methods in the structural health monitoring techniques in aerospace

    Science.gov (United States)

    Riahi, Mohammad; Ahmadi, Alireza

    2016-04-01

    Role of air transport in the development and expansion of world trade leading to economic growth of different countries is undeniable. Continuing the world's trade sustainability without expansion of aerospace is next to impossible. Based on enormous expenses for design, manufacturing and maintenance of different aerospace structures, correct and timely diagnosis of defects in those structures to provide for maximum safety has the highest importance. Amid all this, manufacturers of commercial and even military aircrafts are after production of less expensive, lighter, higher fuel economy and nonetheless, higher safety. As such, two events has prevailed in the aerospace industries: (1) Utilization of composites for the fuselage as well as other airplane parts, (2) using modern manufacturing methods. Arrival of two these points have created the need for upgrading of the present systems as well as innovating newer methods in diagnosing and detection of defects in aerospace structures. Despite applicability of nondestructive testing (NDT) methods in aerospace for decades, due to some limitations in the defect detection's certainty, particularly for composite material and complex geometries, shadow of doubt has fallen on maintaining complete confidence in using NDT. These days, two principal approach are ahead to tackle the above mentioned problems. First, approach for the short range is the creative and combinational mean to increase the reliability of NDT and for the long run, innovation of new methods on the basis of structural health monitoring (SHM) is in order. This has led to new philosophy in the maintenance area and in some instances; field of design has also been affected by it.

  12. Development of modern methods with respect to neutron transport and uncertainty analyses for reactor core calculations. Interim report; Weiterentwicklung moderner Verfahren zu Neutronentransport und Unsicherheitsanalysen fuer Kernberechnungen. Zwischenbericht

    Energy Technology Data Exchange (ETDEWEB)

    Zwermann, Winfried; Aures, Alexander; Bostelmann, Friederike; Pasichnyk, Ihor; Perin, Yann; Velkov, Kiril; Zilly, Matias

    2016-12-15

    This report documents the status of the research and development goals reached within the reactor safety research project RS1536 ''Development of modern methods with respect to neutron transport and uncertainty analyses for reactor core calculations'' as of the 3{sup rd} quarter of 2016. The superordinate goal of the project is the development, validation, and application of neutron transport methods and uncertainty analyses for reactor core calculations. These calculation methods will mainly be applied to problems related to the core behaviour of light water reactors and innovative reactor concepts, in particular fast reactors cooled by liquid metal. The contributing individual goals are the further optimization and validation of deterministic calculation methods with high spatial and energy resolution, the development of a coupled calculation system using the Monte Carlo method for the neutron transport to describe time-dependent reactor core states, the processing and validation of nuclear data, particularly with regard to covariance data, the development, validation, and application of sampling-based methods for uncertainty and sensitivity analyses, the creation of a platform for performing systematic uncertainty analyses for fast reactor systems, as well as the description of states of severe core damage with the Monte Carlo method. Moreover, work regarding the European NURESAFE project, started in the preceding project RS1503, are being continued and completed.

  13. Effect of cantilever geometry on the optical lever sensitivities and thermal noise method of the atomic force microscope.

    Science.gov (United States)

    Sader, John E; Lu, Jianing; Mulvaney, Paul

    2014-11-01

    Calibration of the optical lever sensitivities of atomic force microscope (AFM) cantilevers is especially important for determining the force in AFM measurements. These sensitivities depend critically on the cantilever mode used and are known to differ for static and dynamic measurements. Here, we calculate the ratio of the dynamic and static sensitivities for several common AFM cantilevers, whose shapes vary considerably, and experimentally verify these results. The dynamic-to-static optical lever sensitivity ratio is found to range from 1.09 to 1.41 for the cantilevers studied - in stark contrast to the constant value of 1.09 used widely in current calibration studies. This analysis shows that accuracy of the thermal noise method for the static spring constant is strongly dependent on cantilever geometry - neglect of these dynamic-to-static factors can induce errors exceeding 100%. We also discuss a simple experimental approach to non-invasively and simultaneously determine the dynamic and static spring constants and optical lever sensitivities of cantilevers of arbitrary shape, which is applicable to all AFM platforms that have the thermal noise method for spring constant calibration.

  14. Invisible and microscopic gold in pyrite: Methods and new data for massive sulfide ores of the Urals

    Science.gov (United States)

    Vikentyev, I. V.

    2015-07-01

    Au speciation in sulfides (including "invisible" Au), which mostly controls the loss of Au during ore dressing, is discussed. Modern methods of analysis of Au speciation, with discussion of limitations by locality and sensitivity, are reviewed. The results of sulfide investigation by the methods of scanning and transmission electron microscopy, mass spectrometric analysis with laser ablation (LA-ICP-MS), the thermochemical method (study of ionic Au speciation), and automated "quantitative mineralogy," are demonstrated for weakly metamorphosed VHMS deposits of the Urals (Galkinsk and Uchaly). Significant content of Au is scattered in sulfides, such as pyrite, chalcopyrite, and sphalerite, with quantitative predomination of pyrite. The portion of such "invisible" gold ranges from flakes) with a monocrystal diffraction pattern of some particles and a ring diffraction pattern of other particles was registered in the ores of these deposits by the methods of transmission electron microscopy. The low degree (or absence) of metamorphic recrystallization results in (1) predomination of thin intergrowths of sulfides, which is the main reason for the bad concentration of ores (especially for the Galkinsk deposit) and (2) the high portion of "invisible" gold in the massive sulfide ores, which explains the low yield of Au in copper and zinc concentrates, since it is lost in tailings with predominating pyrite.

  15. Forms And Methods Of Modern Russian Youth Involvement Into The Electoral Process

    Directory of Open Access Journals (Sweden)

    Aleksey D. Maslov

    2015-03-01

    Full Text Available In the present article authors analyzes forms and methods of modern Russian youth involvement in the electoral process. Involving young people in the electoral process is directly related to the problem of increasing the level of political culture in the society. This article presents the main forms of work to attract young people to participate in elections in our country, according to the Central Election Commission (CEC of Russia, some of the regional election commissions, the Russian Public Opinion Research Center (WCIOM. Authors note that at present there are more than one hundred and sixty legislative acts of the Russian Federation, which reflect certain aspects of the state youth policy. All these measures stimulate the political activity of young people, but in our opinion, that is not enough. The fundamental change in the attitude of young people to politics, to the institution of elections is possible only when young people feel like a real part and the subject of transformation processes in our country. In conclusion authors summarizes, that a fundamental change in the relationship of young people to politics, the institution of elections is possible only, when very young feel a real party and the subject of transformation processes in our country. This is possible only when the state is really and not formally prioritizes youth policy. Young people should have a daily state support for education, starting a business, implementation of acquired skills for a decent fee, starting a family, buying a house, etc.

  16. Optimal correction and design parameter search by modern methods of rigorous global optimization

    International Nuclear Information System (INIS)

    Makino, K.; Berz, M.

    2011-01-01

    Frequently the design of schemes for correction of aberrations or the determination of possible operating ranges for beamlines and cells in synchrotrons exhibit multitudes of possibilities for their correction, usually appearing in disconnected regions of parameter space which cannot be directly qualified by analytical means. In such cases, frequently an abundance of optimization runs are carried out, each of which determines a local minimum depending on the specific chosen initial conditions. Practical solutions are then obtained through an often extended interplay of experienced manual adjustment of certain suitable parameters and local searches by varying other parameters. However, in a formal sense this problem can be viewed as a global optimization problem, i.e. the determination of all solutions within a certain range of parameters that lead to a specific optimum. For example, it may be of interest to find all possible settings of multiple quadrupoles that can achieve imaging; or to find ahead of time all possible settings that achieve a particular tune; or to find all possible manners to adjust nonlinear parameters to achieve correction of high order aberrations. These tasks can easily be phrased in terms of such an optimization problem; but while mathematically this formulation is often straightforward, it has been common belief that it is of limited practical value since the resulting optimization problem cannot usually be solved. However, recent significant advances in modern methods of rigorous global optimization make these methods feasible for optics design for the first time. The key ideas of the method lie in an interplay of rigorous local underestimators of the objective functions, and by using the underestimators to rigorously iteratively eliminate regions that lie above already known upper bounds of the minima, in what is commonly known as a branch-and-bound approach. Recent enhancements of the Differential Algebraic methods used in particle

  17. Development of Scanning Ultrafast Electron Microscope Capability.

    Energy Technology Data Exchange (ETDEWEB)

    Collins, Kimberlee Chiyoko [Sandia National Lab. (SNL-CA), Livermore, CA (United States); Talin, Albert Alec [Sandia National Lab. (SNL-CA), Livermore, CA (United States); Chandler, David W. [Sandia National Lab. (SNL-CA), Livermore, CA (United States); Michael, Joseph R. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2016-11-01

    Modern semiconductor devices rely on the transport of minority charge carriers. Direct examination of minority carrier lifetimes in real devices with nanometer-scale features requires a measurement method with simultaneously high spatial and temporal resolutions. Achieving nanometer spatial resolutions at sub-nanosecond temporal resolution is possible with pump-probe methods that utilize electrons as probes. Recently, a stroboscopic scanning electron microscope was developed at Caltech, and used to study carrier transport across a Si p-n junction [ 1 , 2 , 3 ] . In this report, we detail our development of a prototype scanning ultrafast electron microscope system at Sandia National Laboratories based on the original Caltech design. This effort represents Sandia's first exploration into ultrafast electron microscopy.

  18. Martian Microscope

    Science.gov (United States)

    2004-01-01

    The microscopic imager (circular device in center) is in clear view above the surface at Meridiani Planum, Mars, in this approximate true-color image taken by the panoramic camera on the Mars Exploration Rover Opportunity. The image was taken on the 9th sol of the rover's journey. The microscopic imager is located on the rover's instrument deployment device, or arm. The arrow is pointing to the lens of the instrument. Note the dust cover, which flips out to the left of the lens, is open. This approximated color image was created using the camera's violet and infrared filters as blue and red.

  19. A test of Hartnett's revisions to the pubic symphysis and fourth rib methods on a modern sample.

    Science.gov (United States)

    Merritt, Catherine E

    2014-05-01

    Estimating age at death is one of the most important aspects of creating a biological profile. Most adult age estimation methods were developed on North American skeletal collections from the early to mid-20th century, and their applicability to modern populations has been questioned. In 2010, Hartnett used a modern skeletal collection from the Maricopia County Forensic Science Centre to revise the Suchey-Brooks pubic symphysis method and the İşcan et al. fourth rib methods. The current study tests Hartnett's revised methods as well as the original Suchey-Brooks and İşcan et al. methods on a modern sample from the William Bass Skeletal Collection (N = 313, mean age = 58.5, range 19-92). Results show that the Suchey-Brooks and İşcan et al. methods assign individuals to the correct phase 70.8% and 57.5% of the time compared with Hartnett's revised methods at 58.1% and 29.7%, respectively, with correctness scores based on one standard deviation of the mean rather than the entire age range. Accuracy and bias scores are significantly improved for Hartnett's revised pubic symphysis method and marginally better for Hartnett's revised fourth rib method, suggesting that the revised mean ages at death of Hartnett's phases better reflect this modern population. Overall, both Hartnett's revised methods are reliable age estimation methods. For the pubic symphysis, there are significant improvements in accuracy and bias scores, especially for older individuals; however, for the fourth rib, the results are comparable to the original İşcan et al. methods, with some improvement for older individuals. © 2014 American Academy of Forensic Sciences.

  20. In situ detection and characterization of potable water biofilms on materials by microscopic, spectroscopic and electrochemistry methods

    Energy Technology Data Exchange (ETDEWEB)

    Gamby, Jean [Universite Pierre et Marie Curie - Paris 6, CNRS-UPR 15, Laboratoire Interfaces et Systemes Electrochimiques, 4 Place Jussieu, Case Courrier 133, 75252 Paris Cedex 05 (France)], E-mail: jean.gamby@upmc.fr; Pailleret, Alain [Universite Pierre et Marie Curie - Paris 6, CNRS-UPR 15, Laboratoire Interfaces et Systemes Electrochimiques, 4 Place Jussieu, Case Courrier 133, 75252 Paris Cedex 05 (France); Clodic, Carol Boucher; Pradier, Claire-Marie [Universite Pierre et Marie Curie - Paris 6, CNRS-UMR 7609, Laboratoire de Reactivite de Surface, 4 Place Jussieu, Case Courrier 178, 75252 Paris Cedex 05 (France); Tribollet, Bernard [Universite Pierre et Marie Curie - Paris 6, CNRS-UPR 15, Laboratoire Interfaces et Systemes Electrochimiques, 4 Place Jussieu, Case Courrier 133, 75252 Paris Cedex 05 (France)

    2008-12-01

    We studied biofilm formation on stainless steel occurring in a drinking water distribution system which operated in parallel at 20 and 37 deg. C, in order to focus on the effect of temperature rather than on other operational and water quality parameters. A surface conditioning step was followed as a function of time on this material until adhesion of bacterial colonies by using microscopic methods: scanning electron microscopy (SEM) and atomic force microscopy (AFM); a spectroscopic method: polarization modulation infrared reflection absorption spectroscopy (PM-IRRAS), and an electrochemical method: rotating disk electrode (RDE). Correlations between surface analysis, the duration of immersion of the sample and the influence of temperature have been identified clearly before bacterial adhesion. In cold water, these results showed an initial conditioning step of surface occurring during the first 8 days, with detection of superficial acidic functions grafted on surface, until adsorption of proteins. After 12 days, formation of independent bacteria microcolonies, reaching 2-3 {mu}m in length was observed. In tepid water, the first step was reduced to 2 days during which carbonates, acidic functions, and proteins were detected. After 90 days, the biofilm entered in a stable population state, which appeared as a bacteria rich film, including possibly Legionella. The spatial variation of the biofilm was limited as deduced from the thickness determination (about 4 {mu}m for 3-month period), using a RDE. The combination of these different techniques confirms successive steps for biofilm formation on stainless steel in a tap water. Then, we scrutinized the external near environment of bacteria including extracellular polymeric substances (EPS) and then further characterize the morphology of dominant bacteria (shape, size, flagellum) on gold substrate by AFM in air.

  1. A Review of Automatic Methods Based on Image Processing Techniques for Tuberculosis Detection from Microscopic Sputum Smear Images.

    Science.gov (United States)

    Panicker, Rani Oomman; Soman, Biju; Saini, Gagan; Rajan, Jeny

    2016-01-01

    Tuberculosis (TB) is an infectious disease caused by the bacteria Mycobacterium tuberculosis. It primarily affects the lungs, but it can also affect other parts of the body. TB remains one of the leading causes of death in developing countries, and its recent resurgences in both developed and developing countries warrant global attention. The number of deaths due to TB is very high (as per the WHO report, 1.5 million died in 2013), although most are preventable if diagnosed early and treated. There are many tools for TB detection, but the most widely used one is sputum smear microscopy. It is done manually and is often time consuming; a laboratory technician is expected to spend at least 15 min per slide, limiting the number of slides that can be screened. Many countries, including India, have a dearth of properly trained technicians, and they often fail to detect TB cases due to the stress of a heavy workload. Automatic methods are generally considered as a solution to this problem. Attempts have been made to develop automatic approaches to identify TB bacteria from microscopic sputum smear images. In this paper, we provide a review of automatic methods based on image processing techniques published between 1998 and 2014. The review shows that the accuracy of algorithms for the automatic detection of TB increased significantly over the years and gladly acknowledges that commercial products based on published works also started appearing in the market. This review could be useful to researchers and practitioners working in the field of TB automation, providing a comprehensive and accessible overview of methods of this field of research.

  2. In situ detection and characterization of potable water biofilms on materials by microscopic, spectroscopic and electrochemistry methods

    International Nuclear Information System (INIS)

    Gamby, Jean; Pailleret, Alain; Clodic, Carol Boucher; Pradier, Claire-Marie; Tribollet, Bernard

    2008-01-01

    We studied biofilm formation on stainless steel occurring in a drinking water distribution system which operated in parallel at 20 and 37 deg. C, in order to focus on the effect of temperature rather than on other operational and water quality parameters. A surface conditioning step was followed as a function of time on this material until adhesion of bacterial colonies by using microscopic methods: scanning electron microscopy (SEM) and atomic force microscopy (AFM); a spectroscopic method: polarization modulation infrared reflection absorption spectroscopy (PM-IRRAS), and an electrochemical method: rotating disk electrode (RDE). Correlations between surface analysis, the duration of immersion of the sample and the influence of temperature have been identified clearly before bacterial adhesion. In cold water, these results showed an initial conditioning step of surface occurring during the first 8 days, with detection of superficial acidic functions grafted on surface, until adsorption of proteins. After 12 days, formation of independent bacteria microcolonies, reaching 2-3 μm in length was observed. In tepid water, the first step was reduced to 2 days during which carbonates, acidic functions, and proteins were detected. After 90 days, the biofilm entered in a stable population state, which appeared as a bacteria rich film, including possibly Legionella. The spatial variation of the biofilm was limited as deduced from the thickness determination (about 4 μm for 3-month period), using a RDE. The combination of these different techniques confirms successive steps for biofilm formation on stainless steel in a tap water. Then, we scrutinized the external near environment of bacteria including extracellular polymeric substances (EPS) and then further characterize the morphology of dominant bacteria (shape, size, flagellum) on gold substrate by AFM in air

  3. Development of damage evaluation method on the brittle materials for constructions using microscopic structural dynamics and probability theory

    International Nuclear Information System (INIS)

    Arai, Taketoshi

    1997-01-01

    The conventional stress analysis evaluation of the ceramic apparatuses is due to a perfect model of continuous mechanical materials. Such approximate and simplified treatment is thought to be unsufficient with the following two reasons. At first, because of changes of materials mechanical properties with manufacturing conditions and presence of limit in experimentalismic understanding, establishment of quantitative guideline for improvement of materials and structures and general understanding of thermo-mechanical property change due to neutron radiation becomes difficult. The second, because of statistical change of mechanical property and others containing fracture condition at various loading types, judgement standard of conventional deterministic evaluation is apt to be conservative and causes inferior performance and economics of the constructions under their using conditions. Therefore, in this study, following two basic approaches are planned; 1) Preparation of material deformation and fracture model considering correlation between microscopic/mesoscopic damage and macroscopic behavior, and 2) Improvement of the finite element method calculation due to parallel treatment for soundness and reliability evaluation of the construction. (G.K.)

  4. ELECTRON MICROSCOPIC INVESTIGATION OF YTTRIUM ALUMINUM GARNET POWDERS Y3AL5O12, SYNTHESIZED BY SOL–GEL METHOD

    Directory of Open Access Journals (Sweden)

    A. E. Baranchikov

    2015-09-01

    Full Text Available Subject of Study. The paper presents results of characterization for neodymium doped yttrium aluminum garnet nanopowders - YAG:Nd3+ by the method of scanning electronic microscopy. Method. Synthesis of YAG:Nd3+ was carried out by sol-gel method from nitrate or acetate - nitrate solutions with addition of some organic compounds and ammonia as well. Such substances were used as the source ones: oxides of neodymium and yttrium with the content of the basic substance equal to 99.999 %; organic compounds: citric acid with the content of the basic substance not less than 99.0 %; ethylene glycol (99.5%; the ammonium lauryl sulfate (99.0 %; urea (99.0 % of Alfa Aesar, Fluka, Aldrich companies. Oxides of yttrium and neodymium (5 at. % were dissolved in 50% acetic acid, nitrate aluminum was added with a view to the resulting product Y2,85Nd0,15Al5,0O12, the solution was stirred and heated to 60С before reaching its transparency and uniformity. The weight of the portion corresponding to the stoichiometry YAG was 2.0 g. 50 % aqueous solutions of organic substances or 5% NH4OH in a weight ratio of 1:1 to the weight of the garnet were added in aqueous solutions, placed into glass cups. The solutions were thoroughly mixed first using a conventional stirrer, then on ultrasonic installation with simultaneous 60 С heating for 2 hours. Drying of solutions to the consistency of a powder or a thick gel was carried out at 110 С. Then the samples were placed into platinum cups and annealed in a tube furnace at 950 - 1050 С for the period from 0.5 to 2 hours. Additional annealing of the powders in the air at 950 - 1060С were carried out for the purpose of powders clarifying for residual amorphous carbon removal. Main Results. The synthesized powder precursors and powders after annealing were examined using a polarizing microscope to identify anisotropic crystalline phases. X-ray analysis of the synthesized samples was carried out on a DRON - 4 and UDR - 63

  5. Use of traditional and modern contraceptives among childbearing women: findings from a mixed methods study in two southwestern Nigerian states.

    Science.gov (United States)

    Ajayi, Anthony Idowu; Adeniyi, Oladele Vincent; Akpan, Wilson

    2018-05-09

    Contraceptive use has numerous health benefits such as preventing unplanned pregnancies, ensuring optimum spacing between births, reducing maternal and child mortality, and improving the lives of women and children in general. This study examines the level of contraceptive use, its determinants, reasons for non-use of contraception among women in the reproductive age group (18-49 years) in two southwestern Nigerian states. The study adopted an interviewer-administered questionnaire to collect data from 809 participants selected using a 3-stage cluster random sampling technique. We also conducted 46 in-depth interviews. In order to investigate the association between the socio-demographic variables and use of contraceptive methods, we estimated the binary logistic regression models. The findings indicated that knowledge of any methods of contraception was almost universal among the participants. The rates of ever use and current use of contraception was 80 and 66.6%, respectively. However, only 43.9% of the participants had ever used any modern contraceptive methods, considered to be more reliable. The fear of side effects of modern contraceptive methods drove women to rely on less effective traditional methods (withdrawal and rhythm methods). Some women employed crude and unproven contraceptive methods to prevent pregnancies. Our findings show that the rate of contraceptive use was high in the study setting. However, many women chose less effective traditional contraceptive methods over more effective modern contraceptive methods due to fear of side effects of the latter. Patient education on the various options of modern contraceptives, their side effects and management would be crucial towards expanding the family planning services in the study setting.

  6. The extended wedge method: atomic force microscope friction calibration for improved tolerance to instrument misalignments, tip offset, and blunt probes.

    Science.gov (United States)

    Khare, H S; Burris, D L

    2013-05-01

    One of the major challenges in understanding and controlling friction is the difficulty in bridging the length and time scales of macroscale contacts and those of the single asperity interactions they comprise. While the atomic force microscope (AFM) offers a unique ability to probe tribological surfaces in a wear-free single-asperity contact, instrument calibration challenges have limited the usefulness of this technique for quantitative nanotribological studies. A number of lateral force calibration techniques have been proposed and used, but none has gained universal acceptance due to practical considerations, configuration limitations, or sensitivities to unknowable error sources. This paper describes a simple extension of the classic wedge method of AFM lateral force calibration which: (1) allows simultaneous calibration and measurement on any substrate, thus eliminating prior tip damage and confounding effects of instrument setup adjustments; (2) is insensitive to adhesion, PSD cross-talk, transducer/piezo-tube axis misalignment, and shear-center offset; (3) is applicable to integrated tips and colloidal probes; and (4) is generally applicable to any reciprocating friction coefficient measurement. The method was applied to AFM measurements of polished carbon (99.999% graphite) and single crystal MoS2 to demonstrate the technique. Carbon and single crystal MoS2 had friction coefficients of μ = 0.20 ± 0.04 and μ = 0.006 ± 0.001, respectively, against an integrated Si probe. Against a glass colloidal sphere, MoS2 had a friction coefficient of μ = 0.005 ± 0.001. Generally, the measurement uncertainties ranged from 10%-20% and were driven by the effect of actual frictional variation on the calibration rather than calibration error itself (i.e., due to misalignment, tip-offset, or probe radius).

  7. Models and methods for assessing the value of HVDC and MVDC technologies in modern power grids

    Energy Technology Data Exchange (ETDEWEB)

    Makarov, Yuri V. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Elizondo, Marcelo A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); O' Brien, James G. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Huang, Qiuhua [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Kirkham, Harold [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Huang, Zhenyu [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Chinthavali, Madhu [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Suman, Debnath [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Mohan, Nihal [Mid-Continent Independent System Operator (MISO), St. Paul, MN (United States); Hess, Warren [Mid-Continent Independent System Operator (MISO), St. Paul, MN (United States); Duebner, David [Mid-Continent Independent System Operator (MISO), St. Paul, MN (United States); Orser, David [Mid-Continent Independent System Operator (MISO), St. Paul, MN (United States); Brown, Hilary [Mid-Continent Independent System Operator (MISO), St. Paul, MN (United States); Osborn, Dale [Mid-Continent Independent System Operator (MISO), St. Paul, MN (United States); Feltes, James [Siemens, Knoxville, TN (United States); Kurthakoti Chandrashekhara, Divya [Siemens, Knoxville, TN (United States); Zhu, Wenchun [Siemens, Knoxville, TN (United States)

    2017-07-31

    This report reflects the results of U.S. Department of Energy’s (DOE) Grid Modernization project 0074 “Models and methods for assessing the value of HVDC [high-voltage direct current] and MTDC [multi-terminal direct current] technologies in modern power grids.” The work was done by the Pacific Northwest National Laboratory (PNNL) and Oak Ridge National Laboratory (ORNL) in cooperation with Mid-Continent Independent System Operator (MISO) and Siemens. The main motivation of this study was to show the benefit of using direct current (DC) systems larger than those in existence today as they overlap with the alternating current (AC) systems. Proper use of their flexibility in terms of active/reactive power control and fast response can provide much-needed services to the grid at the same time as moving large blocks of energy to take advantage of cost diversity. Ultimately, the project’s success will enable decision-makers and investors to make well-informed decisions regarding this use of DC systems. This project showed the technical feasibility of HVDC macrogrid for frequency control and congestion relief in addition to bulk power transfers. Industry-established models for commonly used technologies were employed, along with high-fidelity models for recently developed HVDC converter technologies; like the modular multilevel converters (MMCs), a voltage source converters (VSC). Models for General Electric Positive Sequence Load Flow (GE PSLF) and Siemens Power System Simulator (PSS/E), widely used analysis programs, were for the first time adapted to include at the same time both Western Electricity Coordinating Council (WECC) and Eastern Interconnection (EI), the two largest North American interconnections. The high-fidelity models and their control were developed in detail for MMC system and extended to HVDC systems in point-to-point and in three-node multi-terminal configurations. Using a continental-level mixed AC-DC grid model, and using a HVDC macrogrid

  8. Microscopic model for the non-linear fluctuating hydrodynamic of 4 He superfluid helium deduced by maximum entropy method

    International Nuclear Information System (INIS)

    Alvarez R, J.T.

    1998-01-01

    This thesis presents a microscopic model for the non-linear fluctuating hydrodynamic of superfluid helium ( 4 He), model developed by means of the Maximum Entropy Method (Maxent). In the chapter 1, it is demonstrated the necessity to developing a microscopic model for the fluctuating hydrodynamic of the superfluid helium, starting from to show a brief overview of the theories and experiments developed in order to explain the behavior of the superfluid helium. On the other hand, it is presented the Morozov heuristic method for the construction of the non-linear hydrodynamic fluctuating of simple fluid. Method that will be generalized for the construction of the non-linear fluctuating hydrodynamic of the superfluid helium. Besides, it is presented a brief summary of the content of the thesis. In the chapter 2, it is reproduced the construction of a Generalized Fokker-Planck equation, (GFP), for a distribution function associated with the coarse grained variables. Function defined with aid of a nonequilibrium statistical operator ρhut FP that is evaluated as Wigneris function through ρ CG obtained by Maxent. Later this equation of GFP is reduced to a non-linear local FP equation from considering a slow and Markov process in the coarse grained variables. In this equation appears a matrix D mn defined with a nonequilibrium coarse grained statistical operator ρhut CG , matrix elements are used in the construction of the non-linear fluctuating hydrodynamics equations of the superfluid helium. In the chapter 3, the Lagrange multipliers are evaluated for to determine ρhut CG by means of the local equilibrium statistical operator ρhut l -tilde with the hypothesis that the system presents small fluctuations. Also are determined the currents associated with the coarse grained variables and furthermore are evaluated the matrix elements D mn but with aid of a quasi equilibrium statistical operator ρhut qe instead of the local equilibrium operator ρhut l -tilde. Matrix

  9. Abstracts book of 4. Poznan Analytical Seminar on Modern Methods of Sample Preparation and Trace Amounts Determination of Elements

    International Nuclear Information System (INIS)

    1995-01-01

    The 4. Poznan Analytical Seminar on Modern Methods of Sample Preparation and Trace Amounts Determination of Elements has been held in Poznan 27-28 April 1995. The new versions of analytical methods have been presented for quantitative determination of trace elements in biological, environmental and geological materials. Also the number of special techniques for sample preparation enables achievement the best precision of analytical results have been shown and discussed

  10. Understanding seafloor morphology using remote high frequency acoustic methods: An appraisal to modern techniques and its effectiveness

    Digital Repository Service at National Institute of Oceanography (India)

    Chakraborty, B.

    Content-Type text/plain; charset=UTF-8 179 Understanding seafloor morphology using remote high frequency acoustic methods: an appraisal to modern techniques and its effectiveness Bishwajit Chakraborty National institute of Oceanography.... The two third of the earth surface i.e. 362 million square km (70 %) is covered by the ocean. In order to understand the seafloor various methods like: application of remote acoustic techniques, seafloor photographic and geological sampling techniques...

  11. Modern Methods of Measuring and Modelling Architectural Objects in the Process of their Valorisation

    Science.gov (United States)

    Zagroba, Marek

    2017-10-01

    As well as being a cutting-edge technology, laser scanning is still developing rapidly. Laser scanners have an almost unlimited range of use in many disciplines of contemporary engineering, where precision and high quality of tasks performed are of the utmost importance. Among these disciplines, special attention is drawn to architecture and urban space studies that is the fields of science which shape the space and surroundings occupied by people, thus having a direct impact on people’s lives. It is more complicated to take measurements with a laser scanner than with traditional methods, where laser target markers or a measuring tape are used. A specific procedure must be followed when measurements are taken with a laser scanner, and the aim is to obtain three-dimensional data about a building situated in a given space. Accuracy, low time consumption, safety and non-invasiveness are the primary advantages of this technology used in the civil engineering practice, when handling both historic and modern architecture. Using a laser scanner is especially important when taking measurements of vast engineering constructions, where an application of traditional techniques would be much more difficult and would require higher time and labour inputs, for example because of some less easily accessible nooks and crannies or due to the geometrical complexity of individual components of a building structure. In this article, the author undertakes the problem of measuring and modelling architectural objects in the process of their valorisation, i.e. the enhancement of their functional, usable, spatial and aesthetic values. Above all, the laser scanning method, by generating results as a point cloud, enables the user to obtain a very detailed, three-dimensional computer image of measured objects, and to make series of analyses and expert investigations, e.g. of the technical condition (deformation of construction elements) as well as the spatial management of the surrounding

  12. India's Modern Slaves: Bonded Labor in India and Methods of Intervention

    Science.gov (United States)

    Boutros, Heidi

    2005-01-01

    Slavery flourishes in the modern world. In nations plagued by debilitating poverty, individuals unable to afford food, clothing, and shelter may be compelled to make a devastating decision: to sell themselves or their children into slavery. Nowhere in the world is this more common than India. Conservative estimates suggest that there are 10…

  13. modern war and the utility of force: challenges, methods and strategy

    African Journals Online (AJOL)

    ismith

    to have adapted well to the new strategic environment, which now results in the ... On the one hand, empirical evidence confirms that military force has ... focussed on the question of how the modern social construct of war should be ... some light on four interrelated paradoxes that are central to the current debate on the.

  14. Defining a realistic control for the chloroform fumigation-incubation method using microscopic counting and 14C-substrates

    International Nuclear Information System (INIS)

    Horwath, W.R.; Paul, E.A.; Harris, D.; Norton, J.; Jagger, L.; National Science Foundation, Logan, UT; Horton, K.A.

    1996-01-01

    Chloroform fumigation-incubation (CFI) has made possible the extensive characterization of soil microbial biomass carbon (C) (MBC). Defining the non-microbial C mineralized in soils following fumigation remains the major limitation of CFI. The mineralization of non-microbial C during CFI was examined by adding 14 C-maize to soil before incubation. The decomposition of the 14 C-maize during a 10-d incubation after fumigation was 22.5% that in non-fumigated control soils. Re-inoculation of the fumigated soil raised 14 C-maize decomposition to 77% that of the unfumigated control. A method was developed which varies the proportion of mineralized C from the unfumigated soil (UF c ) that is subtracted in calculating CFI biomass C. The proportion subtracted (P) varies according to a linear function of the ratio of C mineralized in the fumigated (F c ) and unfumigated samples (F c /UF c ) with two parameters K 1 and K 2 (P = K 1 F c /UF c ) + K 2 ). These parameters were estimated by regression of CFI biomass C, calculated according to the equation MBC = (F c - PUF c )/0.41, against that derived by direct microscopy in a series of California soils. Parameter values which gave the best estimate of microscopic biomass from the fumigation data were K 1 = 0.29 and K 2 = 0.23 (R 2 = 0.87). Substituting these parameter values, the equation can be simplified to MBC = 1.73F c - 0.56UF c . The equation was applied to other CFI data to determine its effect on the measurement of MBC. The use of this approach corrected data that were previously difficult to interpret and helped to reveal temporal trends and changes in MBC associated with soil depth. (author). 40 refs., 4 tabs., 3 figs

  15. Perception of User Criteria in the Context of Sustainability of Modern Methods of Construction Based on Wood

    Directory of Open Access Journals (Sweden)

    Jozef Švajlenka

    2018-01-01

    Full Text Available Recent developments in the construction industry have brought more efficient and sustainable technologies, technological procedures, and materials. An example of this are modern methods of construction, which offer larger production volumes with a higher quality and shorter procurement time. The goal of those methods is to improve construction sustainability through quality improvement, customer satisfaction, shortened construction time, and reduced environmental impact. The main goal of this research is to demonstrate, by means of theoretical assumptions, surveys, and analyses, the sustainability of modern methods of construction based on wood. The work focuses on identifying the user criteria for construction sustainability. Selected user criteria of construction sustainability are applied in a socio-economic survey whose purpose is to determine how users perceive the efficiency of selected construction systems. We evaluate certain user parameters in the context of sustainability by relying on the users of buildings (family houses which have already been built and compare the results with declared design parameters.

  16. The Issue of Age Estimation in a Modern Skeletal Population: Are Even the More Modern Current Aging Methods Satisfactory for the Elderly?

    Science.gov (United States)

    Cappella, Annalisa; Cummaudo, Marco; Arrigoni, Elena; Collini, Federica; Cattaneo, Cristina

    2017-01-01

    The main idea behind age assessment in adults is related to the analysis of the physiological degeneration of particular skeletal structures with age. The main issues with these procedures are due to the fact that they have not been tested on different modern populations and in different taphonomic contexts and that they tend to underestimate the age of older individuals. The purpose of this study was to test the applicability and the reliability of these methods on a contemporary population of skeletal remains of 145 elderly individuals of known sex and age. The results show that, due to taphonomic influences, some skeletal sites showed a lower survival. Therefore, the methods with the highest percentage of applicability were Lovejoy (89.6%) and Rougé-Maillart (81.3%), followed by Suchey-Brooks (59.3%), and those with the lowest percentage of applicability were Beauthier (26.2%) and Iscan (22.7%). In addition, this research has shown how for older adults the study of both acetabulum and auricular surface may be more reliable for aging. This is also in accordance with the fact that auricular surface and the acetabulum are the areas more frequently surviving taphonomic insult. © 2016 American Academy of Forensic Sciences.

  17. Comparative description of the use of modern methods of hormonal contraception for women with excessive body mass

    Directory of Open Access Journals (Sweden)

    I. B. Gridina

    2016-04-01

    Full Text Available Maintenance of reproductive health of women with excessive weight is the actual problem of nowadays and is an important direction of modern medicine. Aim. To analyze the efficiency and acceptability of oral, іntravaginal and transdermal hormonal contraceptives among women with excessive body mass. Methods and results. The tolerability and ease of use of different types of hormonal contraception have been studied in 72 women with excessive body mass to determine the reliability and acceptability of modern hormonal contraceptives. It has been investigated that the effectiveness of hormonal contraceptives according to our data is 100%, none patient was registered with an unwanted pregnancy. The total subjective evaluation of all hormonal contraceptives use were positive: 78.6% of women with excessive body mass who used oral contraceptives, were satisfied with the chosen contraceptive method, 81,8% – were satisfied with intravaginal method, 59,1% – transdermal contraceptive. Conclusions. It has been found that intravaginal contraceptive is most suitable as the drug of first choice for women with overweight compared with oral and transdermal hormonal methods of contraception. This suggests that women with excessive body mass can successfully use modern methods of hormonal contraception. But it is necessary to carry out clinical supervision, during which further clarification on the use of hormonal contraception in women with excessive body mass is possible.

  18. Quantification of incisal tooth wear in upper anterior teeth: conventional vs new method using toolmakers microscope and a three-dimensional measuring technique.

    Science.gov (United States)

    Al-Omiri, Mahmoud K; Sghaireen, Mohd G; Alzarea, Bader K; Lynch, Edward

    2013-12-01

    This study aimed to quantify tooth wear in upper anterior teeth using a new CAD-CAM Laser scanning machine, tool maker microscope and conventional tooth wear index. Fifty participants (25 males and 25 females, mean age = 25 ± 4 years) were assessed for incisal tooth wear of upper anterior teeth using Smith and Knight clinical tooth wear index (TWI) on two occasions, the study baseline and 1 year later. Stone dies for each tooth were prepared and scanned using the CAD-CAM Laser Cercon System. Scanned images were printed and examined under a toolmaker microscope to quantify tooth wear and then the dies were directly assessed under the microscope to measure tooth wear. The Wilcoxon Signed Ranks Test was used to analyze the data. TWI scores for incisal edges were 0-3 and were similar at both occasions. Score 4 was not detected. Wear values measured by directly assessing the dies under the toolmaker microscope (range = 113 - 150 μm, mean = 130 ± 20 μm) were significantly more than those measured from Cercon Digital Machine images (range=52-80 μm, mean = 68 ± 23 μm) and both showed significant differences between the two occasions. Wear progression in upper anterior teeth was effectively detected by directly measuring the dies or the images of dies under toolmaker microscope. Measuring the dies of worn dentition directly under tool maker microscope enabled detection of wear progression more accurately than measuring die images obtained with Cercon Digital Machine. Conventional method was the least sensitive for tooth wear quantification and was unable to identify wear progression in most cases. Copyright © 2013 Elsevier Ltd. All rights reserved.

  19. LOOKING OUT CLASICAL TURKISH POEM ACCORDING TO MODERN ANALYSIS METHODS / DİVAN ŞİİRİ'NE MODERN METİN ÇÖZÜMLEME YÖNTEMLERİNDEN BAKMAK

    Directory of Open Access Journals (Sweden)

    Dr. Dursun Ali TÖKEL

    2007-08-01

    Full Text Available Literature has a characteristic of following the changes of investigations and technology. The great literal changes ın 19th century, effected deeply literature studies. After Saussure, the view of the Occident on language and literature changed. This view changed not only structuralism but also linguistic studies, perceiving and utilizing the linguistic existence. In modern terms, all scientific toughts as modernism, structuralism, post-modernism, seemeiology, semantics bring up new points of view to literary texts. The last quarter of 20th century has been the term of understanding Classical Ottoman Poems not only with the view of traditional commentary methods but also modern analysis methods. This paper gives the panorama of all these analysis, methods of Classical Ottoman Poems.

  20. The Extent of the Application of the Commercial Banks in Aqaba for Modern Methods of Accounting Information Systems

    OpenAIRE

    Muhannad Akram Meqbel Ahmad; Ashraf Mohammad Salem Alrjoub

    2014-01-01

    This study tests the head of departments’ perception towards the relationship between applying accounting information systems and production activities. The results show a positive significant relationship between AIS and production activities (i.e. production design, production planning and control, production operation and cost accounting).This study recommends that using modern methods to develop the skills of the interaction between the users of accounting information systems and between ...

  1. Abstracts of International Conference on Experimental and Computing Methods in High Resolution Diffraction Applied for Structure Characterization of Modern Materials - HREDAMM

    International Nuclear Information System (INIS)

    2004-01-01

    The conference addressed all aspects of high resolution diffraction. The topics of meeting include advanced experimental diffraction methods and computer data analysis for characterization of modern materials as well as the progress and new achievements in high resolution diffraction (X-ray, electrons, neutrons). Application of these methods for characterization of modern materials are widely presented among the invited, oral and poster contributions

  2. The Use Potential of Traditional Building Materials for the Realization of Structures by Modern Methods of Construction

    Science.gov (United States)

    Spišáková, Marcela; Mačková, Daniela

    2015-11-01

    The sustainable building has taken off in recent years with many investors looking for new and different methods of construction. The traditional building materials can be made out of natural materials, while others can help to lower energy costs of the occupant once built. Regardless of what the goal of the investor is, traditional building materials and their use is on the rise. The submitted paper provides an overview of natural building materials and possible modern building systems using these construction materials. Based on the questionnaire survey is defined the use potential of traditional building materials for the realization of the construction by methods of modern constructions and then are determined the drivers and barriers of traditional materials through using modern methods of construction. Considering the analysis of the achieved results, we can identify the gaps in the construction market in Slovakia and also to assess the perception of potential investors in the field of traditional building materials use, which is the purpose of submitted paper.

  3. The Use Potential of Traditional Building Materials for the Realization of Structures by Modern Methods of Construction

    Directory of Open Access Journals (Sweden)

    Spišáková Marcela

    2015-11-01

    Full Text Available The sustainable building has taken off in recent years with many investors looking for new and different methods of construction. The traditional building materials can be made out of natural materials, while others can help to lower energy costs of the occupant once built. Regardless of what the goal of the investor is, traditional building materials and their use is on the rise. The submitted paper provides an overview of natural building materials and possible modern building systems using these construction materials. Based on the questionnaire survey is defined the use potential of traditional building materials for the realization of the construction by methods of modern constructions and then are determined the drivers and barriers of traditional materials through using modern methods of construction. Considering the analysis of the achieved results, we can identify the gaps in the construction market in Slovakia and also to assess the perception of potential investors in the field of traditional building materials use, which is the purpose of submitted paper.

  4. Simple gambling or sophisticated gaming? : applying game analysis methods to modern video slot machine games

    OpenAIRE

    Leppäsalko, Tero

    2017-01-01

    Slot machine games have become the most popular form of gambling worldwide. In Finland, their pervasiveness in public spaces and popularity makes them one of the most common form of gaming. However, in game studies, gambling games are often regarded as borderline games due to the player’s lack of control. In this thesis I ask whether modern video slot machine games can be considered as games and if so, what similarities there are between them and contemporary video games. To find out if m...

  5. A METHODOLOGY FOR IMPROVING PRODUCTIVITY OF THE EXISTING SHIPBUILDING PROCESS USING MODERN PRODUCTION CONCEPTs AND THE AHP METHOD

    Directory of Open Access Journals (Sweden)

    Venesa Stanić

    2017-01-01

    Full Text Available In recent years, shipyards have been facing difficulties in controlling operational costs. To maintain continual operation of all of the facilities, a shipyard must analyze ways of utilizing present production systems for assembling interim vessel products as well as other types of industrial constructions. In the past, new machines continuously improved shipbuilding processes, including software and organizational restructuring, but management continued to search for a modern technological concept that will provide higher productivity, greater profit and overall reduction in costs. In the article the authors suggest implementing Design for Production, Design for Maintainability and Group Technology principles using the Analytical Hierarchy Process (AHP to apply to multi criteria decision making methods as an efficient tool for maintaining international competitiveness in the modern shipbuilding industry. This novel methodology is implemented through four phases. In the first phase, the present situation analysis is suggested for a real shipyard by establishing closest relations among production lines. The second phase presents a constraint analysis that must be evaluated when developing the design solution. The third phase involves generating a typical number of selected alternatives of the Design for Production, Design for Maintainability and Group Technology principles. In the fourth phase, the optimal design solution is selected using the Analytical Hierarchy Process (AHP method. The solution incorporating this modern methodology will improve productivity, profit and lead to decreasing operational costs.

  6. Reviews in Modern Astronomy 12, Astronomical Instruments and Methods at the turn of the 21st Century

    Science.gov (United States)

    Schielicke, Reinhard E.

    The yearbook series Reviews in Modern Astronomy of the Astronomische Gesellschaft (AG) was established in 1988 in order to bring the scientific events of the meetings of the society to the attention of the worldwide astronomical community. Reviews in Modern Astronomy is devoted exclusively to the invited Reviews, the Karl Schwarzschild Lectures, the Ludwig Biermann Award Lectures, and the highlight contributions from leading scientists reporting on recent progress and scientific achievements at their respective research institutes. Volume 12 continues the yearbook series with 16 contributions which were presented during the International Scientific Conference of the AG on ``Astronomical Instruments and Methods at the Turn of the 21st Century'' at Heidelberg from September 14 to 19, 1998

  7. Microscopic enteritis: Bucharest consensus.

    Science.gov (United States)

    Rostami, Kamran; Aldulaimi, David; Holmes, Geoffrey; Johnson, Matt W; Robert, Marie; Srivastava, Amitabh; Fléjou, Jean-François; Sanders, David S; Volta, Umberto; Derakhshan, Mohammad H; Going, James J; Becheanu, Gabriel; Catassi, Carlo; Danciu, Mihai; Materacki, Luke; Ghafarzadegan, Kamran; Ishaq, Sauid; Rostami-Nejad, Mohammad; Peña, A Salvador; Bassotti, Gabrio; Marsh, Michael N; Villanacci, Vincenzo

    2015-03-07

    Microscopic enteritis (ME) is an inflammatory condition of the small bowel that leads to gastrointestinal symptoms, nutrient and micronutrient deficiency. It is characterised by microscopic or sub-microscopic abnormalities such as microvillus changes and enterocytic alterations in the absence of definite macroscopic changes using standard modern endoscopy. This work recognises a need to characterize disorders with microscopic and submicroscopic features, currently regarded as functional or non-specific entities, to obtain further understanding of their clinical relevance. The consensus working party reviewed statements about the aetiology, diagnosis and symptoms associated with ME and proposes an algorithm for its investigation and treatment. Following the 5(th) International Course in Digestive Pathology in Bucharest in November 2012, an international group of 21 interested pathologists and gastroenterologists formed a working party with a view to formulating a consensus statement on ME. A five-step agreement scale (from strong agreement to strong disagreement) was used to score 21 statements, independently. There was strong agreement on all statements about ME histology (95%-100%). Statements concerning diagnosis achieved 85% to 100% agreement. A statement on the management of ME elicited agreement from the lowest rate (60%) up to 100%. The remaining two categories showed general agreement between experts on clinical presentation (75%-95%) and pathogenesis (80%-90%) of ME. There was strong agreement on the histological definition of ME. Weaker agreement on management indicates a need for further investigations, better definitions and clinical trials to produce quality guidelines for management. This ME consensus is a step toward greater recognition of a significant entity affecting symptomatic patients previously labelled as non-specific or functional enteropathy.

  8. INTESTINAL DYSBIOSIS IN CHILDREN WITH FOOD ALLERGY: PATHOGENETIC ASPECTS AND MODERN CORRECTION METHODS

    Directory of Open Access Journals (Sweden)

    S.G. Makarova

    2008-01-01

    Full Text Available Background paper analyses the role of intestinal micro-flora at the stage of forming immunity, the importance of intestinal microflora abnormalities during the periods of allergic diseases development (primarily food allergies, as well as mechanisms of dysbiosis effect on the allergic processes in child's body. The study discusses the mechanisms of treatment and prevention effect of probiotics for cases of child allergic diseases. The work also specifies modern approaches to correcting dysbiotic abnormalities for children with food allergies, reviews the options of diet and medication treatment of food allergy, suggests a new algorithm of gradual treatment that targets correction of dysbiosis in this patient category.Key words: children, food allergy, dysbiosis, probiotics, prebiotics, diet therapy.

  9. [Use of modern contraceptive methods in the Democratic Republic of the Congo: prevalence and barriers in the health zone of Dibindi, Mbuji-Mayi].

    Science.gov (United States)

    Ntambue, Abel Mukengeshayi; Tshiala, Rachel Ngalula; Malonga, Françoise Kaj; Ilunga, Tabitha Mpoyi; Kamonayi, Josaphat Mulumba; Kazadi, Simon Tshimankinda; Matungulu, Charles Matungu; Musau, Angel Nkola; Mulamba, Diese; Dramaix-Wilmet, Michèle; Donnen, Philippe

    2017-01-01

    This study aimed to determine modern contraceptive prevalence and the barriers to using modern contraceptive methods among the couples in Dibindi health zone, Mbuji-Mayi, in the Democratic Republic of the Congo. We conducted a cross-sectional descriptive study from May to June 2015. Nonpregnant married women aged 15-49 years old at the time of the investigation, living in Dibindi health zone for two years and having freely consented to participate in the study were included. Data were collected by open-ended interview of these women. Modern contraceptive prevalence was referred to women who were currently using, at the time of the investigation, modern contraceptives. The comparison between proportions was performed at the significance threshold of 5%. Bonferroni's test was used to compare, two by two, the proportions of barriers to using modern contraceptive methods. Modern contraceptive prevalence in Dibindi was 18.4% in 2015. It was low with regard to family planning services available in this health zone. Several women refused to use modern contraceptive methods despite available information because of their desire for motherhood, religious prohibition, opposition on the part of their husband and fear of side effects. Sufficient client-centered or couple-centered information and family planning information should be strengthened in order to eliminate the false beliefs and to increase the use of modern contraceptive methods.

  10. Photon scanning tunneling microscope in combination with a force microscope

    NARCIS (Netherlands)

    Moers, M.H.P.; Moers, M.H.P.; Tack, R.G.; van Hulst, N.F.; Bölger, B.; Bölger, B.

    1994-01-01

    The simultaneous operation of a photon scanning tunneling microscope with an atomic force microscope is presented. The use of standard atomic force silicon nitride cantilevers as near-field optical probes offers the possibility to combine the two methods. Vertical forces and torsion are detected

  11. Vegetative-vascular dystonia: diagnosis and treatment with the inclusion of modern methods of physiotherapy

    Directory of Open Access Journals (Sweden)

    N. I. Samosyuk

    2015-07-01

      В статье рассматриваются вопросы нейроциркуляторной дистонии и вегетативно-сосудистой дистонии, нозологическая принадлежность которых широко дискутируется в литературе. Авторы показывают в данной работе формирование клинического представления от «ВСД» и «НЦД», приводят классификацию, особенности их клинического течения и методики современной физиотерапии. Статья может представлять интерес широкому кругу врачей: неврологам, терапевтам, семейным врачам, врачам общей практики, студентам старших курсов медицинских ВУЗов и др.   Ключевые слова: вегетативно-сосудистая дистония, вегето-сосудистая дистония, диагностика, лечение, физиотерапия.   Abstract   The article discusses using neuro-circulator dystonia and vegetative-vascular dystonia, nosologic belonging which is widely discussed in the literature. In this paper, the authors show the formation of the clinical presentation of "VCD" and "NCD", lead classification, peculiarities of their clinical evolution and modern methods of physiotherapy. The article may be of interest to a wide range of doctors: neurologists, general practitioners, family doctors, physicians, undergraduate students of medical universities, etc.   Key words: vegetative-vascular dystonia, vegeto-vascular dystonia, diagnosis, treatment, physiotherapy.     Содержание   Вступление Соматоформные расстройства Лечение расстройств,

  12. Optical method for distance and displacement measurements of the probe-sample separation in a scanning near-field optical microscope

    International Nuclear Information System (INIS)

    Santamaria, L.; Siller, H. R.; Garcia-Ortiz, C. E.; Cortes, R.; Coello, V.

    2016-01-01

    In this work, we present an alternative optical method to determine the probe-sample separation distance in a scanning near-field optical microscope. The experimental method is based in a Lloyd’s mirror interferometer and offers a measurement precision deviation of ∼100 nm using digital image processing and numerical analysis. The technique can also be strategically combined with the characterization of piezoelectric actuators and stability evaluation of the optical system. It also opens the possibility for the development of an automatic approximation control system valid for probe-sample distances from 5 to 500 μm.

  13. Microscopic evaluation of methods of fixation and preservation of vaginal smears taken from normal women submitted to radiotherapy for uterine cervical cancer

    International Nuclear Information System (INIS)

    Costa, O.L.N.; Baruffi, I.; Valeri, V.; Parente, J.V.

    1983-01-01

    Two methods were evaluated for fixation and conservation of vaginal smears of normal and irradiated women for periods as long as four months. An initial fixation was used with 95% alcohol for 24 hours followed by either air storage or 0,5% alcohol - ether celoidina solution coating. It is concluded that through microscopic evaluation, the smears of non-irradiated women treated by both methods in long run observation are only worthwhile for oncotic studies. On the other hand, the smears of irradiated women are not valid either for hormonal or oncotic analysis. (Author) [pt

  14. Optical method for distance and displacement measurements of the probe-sample separation in a scanning near-field optical microscope

    Energy Technology Data Exchange (ETDEWEB)

    Santamaria, L.; Siller, H. R. [Tecnológico de Monterrey, Eugenio Garza Sada 2501 Sur, Monterrey, N.L., 64849 (Mexico); Garcia-Ortiz, C. E., E-mail: cegarcia@cicese.mx [CONACYT Research Fellow – CICESE, Unidad Monterrey, Alianza Centro 504, Apodaca, NL, 66629 (Mexico); Cortes, R.; Coello, V. [CICESE, Unidad Monterrey, PIIT, Alianza Centro 504, Apodaca, NL, 66629 (Mexico)

    2016-04-15

    In this work, we present an alternative optical method to determine the probe-sample separation distance in a scanning near-field optical microscope. The experimental method is based in a Lloyd’s mirror interferometer and offers a measurement precision deviation of ∼100 nm using digital image processing and numerical analysis. The technique can also be strategically combined with the characterization of piezoelectric actuators and stability evaluation of the optical system. It also opens the possibility for the development of an automatic approximation control system valid for probe-sample distances from 5 to 500 μm.

  15. Spirituality Phenomenon and the Ideal-Realism Method in Modern Education

    Directory of Open Access Journals (Sweden)

    A. P. Vetoshkin

    2012-01-01

    Full Text Available The paper is devoted to the spiritual revival of modern Russia. In the author’s view, the Russian Idea with its basic principles, moral, spiritual and semantic concepts should provide the guidelines for education, upbringing and the youth policy, guaranteeing the spiritual transformation and mobilization of the moral power for the benefit of the motherland, local society and family, as well as the personal growth. The theoretical and methodological bases for developing and implementing the above idea could be found in Russian national religious and philosophic thinking with its balanced dialectics of spiritual and social aspects. The experience of the ideal-realism, as the leading trend of the national spiritual culture, is being analyzed and summarized. The correlation between the ideal and material in social and individual life is demonstrated along with the dialectics and wholeness of the divine and human, religious and secular, ecclesiastical and civil.The author addresses the philosophic heritage of I. A. Ilyin, V. S. Solovyev, S. N. Trubetskoy, S. N. Bulgakov, N. A. Berdyayev, N. O. Losskiy etc, and regards spirituality as the basic defining, systematic and leading origin of the whole socio-historical process including human being formation and development, education and upbringing. 

  16. Modernity after Modernity

    Directory of Open Access Journals (Sweden)

    Marin Dinu

    2007-08-01

    Full Text Available A strategy for the second modernization raises, beyond objectives, a series of epistemicresponsibilities. It is known that modernization stemming from the Enlightment had, among other things,the pretense that it is a project which is self-legitimating. Its profound rationales are the only justification.Referential self-centering proved to be the one that made possible a practice of the new. Modernizationhaving the function of renouncing myth – meaning an eliminatory formula for the past – and thefixation in the opportunity and potentiality of the present, seemed to close an insoluble but extremelyengrossing problem: that of a propensity towards utopia, of the risky escape towards the future. Thetraditionalization of the new constitutes a support for the daring to break out of the captivity of themoment.Modernization becomes the experience of combining the new which, thus, creates a succession ofpresent times. The future is no longer the result of fantasy, but a system’s direct expression to combine thenew. Therefore the future is an option for one or another model of the present, often tested previouslysomewhere else. In a non-metaphysical way, the future can be seen, touched, tried, lived by simplegeographical movement. The sense of evolution has de-temporalized taking the form of the concomitant,parallel, enclosed, neighboring space. We just have to be in the trend, to evolve in the context.Globalization defines the context and its conception – as a project of the second modernity – showsus the trends. The problem is how to understand the context in order to find the sense of the trend. Are wethe load the sense with the values of the first modernity or will we have to turn to the values of anothermodernity? Why do we have to move away from the significance of the processes which made up the firstmodernity? How do we relate to the content of the new context in which the structural trends of today’sworld are taking place? What is the

  17. Modern teaching for modern education

    OpenAIRE

    Mirascieva, Snezana

    2016-01-01

    Carrying the epithet of being contemporary education today means modern teaching. If modern education is a state in the field of education of all its elements, then teaching will also be a state with its own special features defining it as modern. The main issues of concern in this paper relate to what constitutes modern teaching, which features determine it as being modern, and how much is teaching today following the trend of modernization.

  18. Proper alignment of the microscope.

    Science.gov (United States)

    Rottenfusser, Rudi

    2013-01-01

    The light microscope is merely the first element of an imaging system in a research facility. Such a system may include high-speed and/or high-resolution image acquisition capabilities, confocal technologies, and super-resolution methods of various types. Yet more than ever, the proverb "garbage in-garbage out" remains a fact. Image manipulations may be used to conceal a suboptimal microscope setup, but an artifact-free image can only be obtained when the microscope is optimally aligned, both mechanically and optically. Something else is often overlooked in the quest to get the best image out of the microscope: Proper sample preparation! The microscope optics can only do its job when its design criteria are matched to the specimen or vice versa. The specimen itself, the mounting medium, the cover slip, and the type of immersion medium (if applicable) are all part of the total optical makeup. To get the best results out of a microscope, understanding the functions of all of its variable components is important. Only then one knows how to optimize these components for the intended application. Different approaches might be chosen to discuss all of the microscope's components. We decided to follow the light path which starts with the light source and ends at the camera or the eyepieces. To add more transparency to this sequence, the section up to the microscope stage was called the "Illuminating Section", to be followed by the "Imaging Section" which starts with the microscope objective. After understanding the various components, we can start "working with the microscope." To get the best resolution and contrast from the microscope, the practice of "Koehler Illumination" should be understood and followed by every serious microscopist. Step-by-step instructions as well as illustrations of the beam path in an upright and inverted microscope are included in this chapter. A few practical considerations are listed in Section 3. Copyright © 2013 Elsevier Inc. All rights

  19. Modern methods of overlay welding for corrosion protection of power generating equipment

    International Nuclear Information System (INIS)

    Ershov, A.V.; Shul'man, I.E.; Potapov, N.N.

    1989-01-01

    Methods for overlay welding of inner surfaces of power equipment for corrosion protection are analysed. Various methods of electroslag overlay welding by a band electrode (overlay welding by two-electrode bands by a wide band with magnetic control, by an electrode band with high melting velocity) are marked to be the most perspective for cladding of NPP vessel equipment

  20. CISM-Course on Modern Optical Methods in Experimental Solid Mechanics

    CERN Document Server

    2000-01-01

    The book covers the theories and physics of advanced new optical measuring methods and problems of experimental performance, recent achievements in the basic interferometric methods holography, speckle-interferometry, shearography as well as linear/non-linear photoelasticity and photoviscoelasticity, Moiré- and grid-techniques. It deals with theory and application of digital image processing, methods of data recording, data processing and -visualisation, with mathematical/numerical procedures for final evaluation of digitised measured data and the principle of hybrid techniques. It introduces into the new perceptions of methods in experimental solid mechanics and it should encourage scientists to deal intensively with the theories for further developments, and enables practitioners, to understand theory and physics of the new achievements at least and to apply the methods in research als well as in developments in practice.

  1. Fast and precise method of contingency ranking in modern power system

    DEFF Research Database (Denmark)

    Rather, Zakir Hussain; Chen, Zhe; Thøgersen, Paul

    2011-01-01

    Contingency Analysis is one of the most important aspect of Power System Security Analysis. This paper presents a fast and precise method of contingency ranking for effective power system security analysis. The method proposed in this research work takes due consideration of both apparent power o...... is based on realistic approach taking practical situations into account. Besides taking real situations into consideration the proposed method is fast enough to be considered for on-line security analysis.......Contingency Analysis is one of the most important aspect of Power System Security Analysis. This paper presents a fast and precise method of contingency ranking for effective power system security analysis. The method proposed in this research work takes due consideration of both apparent power...

  2. Computer modeling in free spreadsheets OpenOffice.Calc as one of the modern methods of teaching physics and mathematics cycle subjects in primary and secondary schools

    Directory of Open Access Journals (Sweden)

    Markushevich M.V.

    2016-10-01

    Full Text Available the article details the use of such modern method of training as computer simulation applied to modelling of various kinds of mechanical motion of a material point in the free spreadsheet OpenOffice.org Calc while designing physics and computer science lessons in primary and secondary schools. Particular attention is paid to the application of computer modeling integrated with other modern teaching methods.

  3. PIXE and PGAA - Complementary methods for studies on ancient glass artefacts (from Byzantine, late medieval to modern Murano glass)

    Science.gov (United States)

    Constantinescu, Bogdan; Cristea-Stan, Daniela; Szőkefalvi-Nagy, Zoltán; Kovács, Imre; Harsányi, Ildikó; Kasztovszky, Zsolt

    2018-02-01

    Combined external milli-beam Particle Induced X-ray Emission (PIXE) and Prompt Gamma Activation Analysis (PGAA) analysis was applied to characterize the composition of paste and colorants from some fragments of Byzantine bracelets (10th-12th Centuries AD), late medieval (17th-18th Centuries AD) and modern Murano glass pieces. As fluxes, PGAA revealed the samples are soda-lime glass, except four samples - two medieval vessel white shards and two dark Byzantine fragments of bracelets - which have potash flux. Aluminium was detected in various proportions in all samples indicating different sources for the added sand. The presence of Magnesium is relevant only in one bracelet fragment suggesting the use of plant (wood?) ash and confirming that the Byzantine bracelet is manufactured from the mixture of both types of glass (natron and plant ash based). PGAA also indicated the presence of low quantities of Cadmium, high level of Arsenic and Lead (possibly lead arsenate) in one medieval sample and of ZnO in Murano glass, and of CoO traces (maximum 0.1%) in all blue-colored Byzantine, late medieval to modern Murano glass artefacts. PIXE confirmed the use of small quantities of CoO for blue color, indicated Manganese combined with Iron for dark glass, Copper for green, Lead, Tin and an Arsenic compound (orpiment?) for yellow and in the case of modern Murano glass Selenium and Cadmium to obtain a reddish color. Despite PIXE - PIGE combination is probably the best one for glass analysis, our external milli-PIXE - PGAA methods proved to be adequate complementary tools to determine many chemical elements from glass composition - Si, Na, K, Ca, Al, Mg, various metallic oxides.

  4. Modern nonparametric, robust and multivariate methods festschrift in honour of Hannu Oja

    CERN Document Server

    Taskinen, Sara

    2015-01-01

    Written by leading experts in the field, this edited volume brings together the latest findings in the area of nonparametric, robust and multivariate statistical methods. The individual contributions cover a wide variety of topics ranging from univariate nonparametric methods to robust methods for complex data structures. Some examples from statistical signal processing are also given. The volume is dedicated to Hannu Oja on the occasion of his 65th birthday and is intended for researchers as well as PhD students with a good knowledge of statistics.

  5. Assessment of modern methods of human factor reliability analysis in PSA studies

    International Nuclear Information System (INIS)

    Holy, J.

    2001-12-01

    The report is structured as follows: Classical terms and objects (Probabilistic safety assessment as a framework for human reliability assessment; Human failure within the PSA model; Basic types of operator failure modelled in a PSA study and analyzed by HRA methods; Qualitative analysis of human reliability; Quantitative analysis of human reliability used; Process of analysis of nuclear reactor operator reliability in a PSA study); New terms and objects (Analysis of dependences; Errors of omission; Errors of commission; Error forcing context); and Overview and brief assessment of human reliability analysis (Basic characteristics of the methods; Assets and drawbacks of the use of each of HRA method; History and prospects of the use of the methods). (P.A.)

  6. Knowledge and use of modern family planning methods by rural women in Zambia

    Directory of Open Access Journals (Sweden)

    C. Mubita-Ngoma

    2010-09-01

    Full Text Available The main aim of the study was to determine knowledge and use of modem contractive methods among reproductive age group rural women in Zambia. The study is a descriptive cross-sectional study of 105 randomly selected rural women. Data was collected using semi-structured interview schedule and analyzed using EPI Info version 6 statistical packages. The findings revealed that 63% of the respondents were within the age group 21-35 years, 65% were married and 64% were peasant farmers. 90% of the respondents had heard about modem contraceptives and their main source of information was the Health worker (62%. 76% of the respondents stated that modem contraceptive methods could be obtained from public health facilities. 56% of the respondents were currently using modem contraceptive methods and 46% were not using modem contraceptive methods. Reasons for non use of contraceptive methods were religious beliefs (50%, partner disapproval (30% and side effects (20%. The results showed a relationship between educational level and use of contraceptives (Chi-square 7.83, df = 3, P < 0.05 and spouse approval or support of contractive methods and use of contraceptive (Chisquare 5.9, df = 2, P < 0.05. Therefore, efforts to promote modem contraceptive use among the rural women should be intensified to overcome barriers to contraceptive use and should involve men.

  7. Potentials and limits of modern tomographic methods (CT, MR, PET) in molecular imaging

    International Nuclear Information System (INIS)

    Hentschel, M.; Paul, D.; Moser, E.; Brink, I.

    2007-01-01

    The present survey gives an introduction into the basics of computed tomography, magnetic resonance tomography and positron emission tomography. The current potentials of these methods in relation to their temporal, spatial and contrast resolutions as well as their sensitivities within clinical routine and experimental studies (in vitro, ex vivo) will be presented. Computed tomography constitutes the anatomical reference method with well defined contrast, high spatial resolution but low sensitivity (10 -2 mol/l) for functional and molecular imaging. Magnetic resonance tomography represents the anatomical method for research with variable tissue contrast, physiological image information, highest spatial resolution but moderate sensitivity (10 -3 -10 -5 mol/l) for functional and molecular imaging. Positron emission tomography offers good suitability for molecular imaging due to highest sensitivity (10 -11 -10 -12 mol/l). However, the spatial resolution of positron emission tomography is low. (orig.)

  8. Detection of Theileria equi and Babesia caballi using microscopic and molecular methods in horses in suburb of Urmia, Iran

    Directory of Open Access Journals (Sweden)

    Farnaz Malekifard

    2014-06-01

    Full Text Available Equine piroplasmosis is a severe disease of horses caused by the intra-erythrocyte protozoan, Theileria equi and Babesia caballi. The aim of this study was to identify equine piroplasmosis based on molecular and morphometrical features in horses in suburb of Urmia, West Azerbaijan province, Iran. From April to September 2011, a total number of 240 blood samples were collected randomly from horses of 25 villages. The specimens were transferred to the laboratory and the blood smears stained with Geimsa, and the morphological and biometrical data of parasite in any infected erythrocyte were considered. Extracted DNA from each blood sample was used in multiplex PCR in order to confirm the presence of B. caballi and T. equi. Microscopic observation on 240 blood smears determined that 15 (6.25% and 5 (2.80% samples were infected by T. equi and B. caballi, respectively. The mixed infections occurred in 2 (0.83% samples. The results of the PCR assays showed 26 (10.83%, 14 (5.83% and 4 (1.66% were distinguished as T. equi, B. caballi and mixed infection, respectively. Differences in infection rates were statistically nonsignificant between male and female horses and among different age groups. Our findings indicated that T. equi and B. caballi were prevalent in horse population.

  9. Use of Modern Methods of Credit Portfolio Risk Management in Commercial Banks of Russian Federation

    Directory of Open Access Journals (Sweden)

    Dmitrii S. Melnyk

    2013-01-01

    Full Text Available The article deals with the structure and factors of credit portfolio risk, analyses existing models of portfolio risk assessment and develops recommendations on the implementation of risk management adapted methods, presents recommendations on the optimization of the approach to credit risk minimization in Russian banking system.

  10. Performance evaluation of the zero-multipole summation method in modern molecular dynamics software.

    Science.gov (United States)

    Sakuraba, Shun; Fukuda, Ikuo

    2018-05-04

    The zero-multiple summation method (ZMM) is a cutoff-based method for calculating electrostatic interactions in molecular dynamics simulations, utilizing an electrostatic neutralization principle as a physical basis. Since the accuracies of the ZMM have been revealed to be sufficient in previous studies, it is highly desirable to clarify its practical performance. In this paper, the performance of the ZMM is compared with that of the smooth particle mesh Ewald method (SPME), where the both methods are implemented in molecular dynamics software package GROMACS. Extensive performance comparisons against a highly optimized, parameter-tuned SPME implementation are performed for various-sized water systems and two protein-water systems. We analyze in detail the dependence of the performance on the potential parameters and the number of CPU cores. Even though the ZMM uses a larger cutoff distance than the SPME does, the performance of the ZMM is comparable to or better than that of the SPME. This is because the ZMM does not require a time-consuming electrostatic convolution and because the ZMM gains short neighbor-list distances due to the smooth damping feature of the pairwise potential function near the cutoff length. We found, in particular, that the ZMM with quadrupole or octupole cancellation and no damping factor is an excellent candidate for the fast calculation of electrostatic interactions. © 2018 Wiley Periodicals, Inc. © 2018 Wiley Periodicals, Inc.

  11. Modern summation methods and the computation of 2- and 3-loop Feynman diagrams

    International Nuclear Information System (INIS)

    Ablinger, Jakob; Schneider, Carsten; Bluemlein, Johannes; Klein, Sebastian

    2010-06-01

    By symbolic summation methods based on difference fields we present a general strategy that transforms definite multi-sums, e.g., in terms of hypergeometric terms and harmonic sums, to indefinite nested sums and products. We succeeded in this task with all our concrete calculations of 2-loop and 3-loop massive single scale Feynman diagrams with local operator insertion. (orig.)

  12. A modern mathematical method for filtering noise in low count experiments

    Directory of Open Access Journals (Sweden)

    Medhat Moustafa E.

    2015-01-01

    Full Text Available In the proposed work, a novel application of a numerical and functional analysis based on the discrete wavelet transform is discussed. The mathematics of improving signals and removing noises are described. Results obtained show that the method used in a variety of gamma spectra is superior to other techniques.

  13. Modern methods for the determination of physicochemical states of microelements in natural waters

    International Nuclear Information System (INIS)

    Polyakov, Evgenii V; Egorov, Yurii V

    2003-01-01

    The state-of-the-art in studies on the determination of ion-molecular and colloidal forms of microelements in aqueous solutions is analysed. Instrumental and hyphenated methods for the determination of such forms of microelements as aqua-ions, complexes, true and adsorption colloids are considered.

  14. Modern Summation Methods and the Computation of 2- and 3-loop Feynman Diagrams

    International Nuclear Information System (INIS)

    Ablinger, Jakob; Bluemlein, Johannes; Klein, Sebastian; Schneider, Carsten

    2010-01-01

    By symbolic summation methods based on difference fields we present a general strategy that transforms definite multi-sums, e.g., in terms of hypergeometric terms and harmonic sums, to indefinite nested sums and products. We succeeded in this task with all our concrete calculations of 2-loop and 3-loop massive single scale Feynman diagrams with local operator insertion.

  15. Modern summation methods and the computation of 2- and 3-loop Feynman diagrams

    Energy Technology Data Exchange (ETDEWEB)

    Ablinger, Jakob; Schneider, Carsten [Linz Univ. (AT). Research Inst. for Symbolic Computation (RISC); Bluemlein, Johannes [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany); Klein, Sebastian [RWTH Aachen (Germany). Inst. fuer Theoretische Teilchenphysik und Kosmologie

    2010-06-15

    By symbolic summation methods based on difference fields we present a general strategy that transforms definite multi-sums, e.g., in terms of hypergeometric terms and harmonic sums, to indefinite nested sums and products. We succeeded in this task with all our concrete calculations of 2-loop and 3-loop massive single scale Feynman diagrams with local operator insertion. (orig.)

  16. Classical and modern optimization methods in minimum weight design of elastic rotating disk with variable thickness and density

    International Nuclear Information System (INIS)

    Jafari, S.; Hojjati, M.H.; Fathi, A.

    2012-01-01

    Rotating disks work mostly at high angular velocity and this results a large centrifugal force and consequently induce large stresses and deformations. Minimizing weight of such disks yields to benefits such as low dead weights and lower costs. This paper aims at finding an optimal disk profiles for minimum weight design using the Karush-Kuhn-Tucker method (KKT) as a classical optimization method, simulated annealing (SA) and particle swarm optimization (PSO) as two modern optimization techniques. Some semi-analytical solutions for the elastic stress distribution in a rotating annular disk with uniform and variable thickness and density proposed by the authors in the previous works have been used. The von Mises failure criterion of optimum disk is used as an inequality constraint to make sure that the rotating disk does not fail. The results show that the minimum weight obtained for all three methods is almost identical. The KKT method gives a profile with slightly less weight (6% less than SA and 1% less than PSO) while the implementation of PSO and SA methods are easier and provide more flexibility compared with those of the KKT method. The effectiveness of the proposed optimization methods is shown. - Highlights: ► Karush-Kuhn-Tucker, simulated annealing and particle swarm methods are used. ► The KKT gives slightly less weight (6% less than SA and 1% less than PSO). ► Implementation of PSO and SA methods are easier and provide more flexibility. ► The effectiveness of the proposed optimization methods is shown.

  17. Classical and modern optimization methods in minimum weight design of elastic rotating disk with variable thickness and density

    Energy Technology Data Exchange (ETDEWEB)

    Jafari, S. [Faculty of Mechanical Engineering, Babol University of Technology, P.O. Box 484, Babol (Iran, Islamic Republic of); Hojjati, M.H., E-mail: Hojjati@nit.ac.ir [Faculty of Mechanical Engineering, Babol University of Technology, P.O. Box 484, Babol (Iran, Islamic Republic of); Fathi, A. [Faculty of Mechanical Engineering, Babol University of Technology, P.O. Box 484, Babol (Iran, Islamic Republic of)

    2012-04-15

    Rotating disks work mostly at high angular velocity and this results a large centrifugal force and consequently induce large stresses and deformations. Minimizing weight of such disks yields to benefits such as low dead weights and lower costs. This paper aims at finding an optimal disk profiles for minimum weight design using the Karush-Kuhn-Tucker method (KKT) as a classical optimization method, simulated annealing (SA) and particle swarm optimization (PSO) as two modern optimization techniques. Some semi-analytical solutions for the elastic stress distribution in a rotating annular disk with uniform and variable thickness and density proposed by the authors in the previous works have been used. The von Mises failure criterion of optimum disk is used as an inequality constraint to make sure that the rotating disk does not fail. The results show that the minimum weight obtained for all three methods is almost identical. The KKT method gives a profile with slightly less weight (6% less than SA and 1% less than PSO) while the implementation of PSO and SA methods are easier and provide more flexibility compared with those of the KKT method. The effectiveness of the proposed optimization methods is shown. - Highlights: Black-Right-Pointing-Pointer Karush-Kuhn-Tucker, simulated annealing and particle swarm methods are used. Black-Right-Pointing-Pointer The KKT gives slightly less weight (6% less than SA and 1% less than PSO). Black-Right-Pointing-Pointer Implementation of PSO and SA methods are easier and provide more flexibility. Black-Right-Pointing-Pointer The effectiveness of the proposed optimization methods is shown.

  18. Modern analytical methods for the detection of food fraud and adulteration by food category.

    Science.gov (United States)

    Hong, Eunyoung; Lee, Sang Yoo; Jeong, Jae Yun; Park, Jung Min; Kim, Byung Hee; Kwon, Kisung; Chun, Hyang Sook

    2017-09-01

    This review provides current information on the analytical methods used to identify food adulteration in the six most adulterated food categories: animal origin and seafood, oils and fats, beverages, spices and sweet foods (e.g. honey), grain-based food, and others (organic food and dietary supplements). The analytical techniques (both conventional and emerging) used to identify adulteration in these six food categories involve sensory, physicochemical, DNA-based, chromatographic and spectroscopic methods, and have been combined with chemometrics, making these techniques more convenient and effective for the analysis of a broad variety of food products. Despite recent advances, the need remains for suitably sensitive and widely applicable methodologies that encompass all the various aspects of food adulteration. © 2017 Society of Chemical Industry. © 2017 Society of Chemical Industry.

  19. MODERN METHOD OF DETECTION OF TAXONOMIC COMPOSITION OF MICROBIALS IN URINARY WAYS OF WOMEN

    OpenAIRE

    Bendas, V. V.; Stefak, Ya. P.; Moysyuk, V. D.; Mihalchan, A. B.

    2018-01-01

    In case of necessity to conduct a more qualitative examination of women with inflammatory processes, which are localized in the organs of the genitourinary system and in order to obtain an objective assessment of normal and pathogenic microflora in the urogenital pathways of a woman, a polymerase chain reaction method is proposed with the use of the diagnostic test of the system "Femoflore-16". This system help identification of Lactobacillus spp., Enterobacterium spp., Streptococcus spp., St...

  20. Modern architectures for intelligent systems: reusable ontologies and problem-solving methods.

    Science.gov (United States)

    Musen, M A

    1998-01-01

    When interest in intelligent systems for clinical medicine soared in the 1970s, workers in medical informatics became particularly attracted to rule-based systems. Although many successful rule-based applications were constructed, development and maintenance of large rule bases remained quite problematic. In the 1980s, an entire industry dedicated to the marketing of tools for creating rule-based systems rose and fell, as workers in medical informatics began to appreciate deeply why knowledge acquisition and maintenance for such systems are difficult problems. During this time period, investigators began to explore alternative programming abstractions that could be used to develop intelligent systems. The notions of "generic tasks" and of reusable problem-solving methods became extremely influential. By the 1990s, academic centers were experimenting with architectures for intelligent systems based on two classes of reusable components: (1) domain-independent problem-solving methods-standard algorithms for automating stereotypical tasks--and (2) domain ontologies that captured the essential concepts (and relationships among those concepts) in particular application areas. This paper will highlight how intelligent systems for diverse tasks can be efficiently automated using these kinds of building blocks. The creation of domain ontologies and problem-solving methods is the fundamental end product of basic research in medical informatics. Consequently, these concepts need more attention by our scientific community.

  1. Comparison of modern and traditional methods of soilsorption complex measurement : the basis of long -term studies and modelling

    Directory of Open Access Journals (Sweden)

    Kučera Aleš

    2014-03-01

    Full Text Available This paper presents the correlations between two different analytical methods of assessing soil nutrient contents. Soil nutrient content measurements measured using the flame atomic absorption spectrometry (FAAS method, which uses barium chloride extraction, were compared with those of the now-unused Gedroiz method, which uses ammonium chloride extraction (calcium by titration, magnesium, potassium and sodium by weighing. Natural forest soils from the Ukrainian Carpathians at the localities of Javorník and Pop Ivan were used. Despite the risk of analysis errors during the complicated analytical procedure, the results showed a high level of correlation between different nutrient content measurements across the whole soil profile. This allows concentration values given in different studies to be linearly recalculated on results of modern method. In this way, results can be used to study soil’s chemical changes over time from the soil samples that were analysed in the past using labour-intensive and time-consuming methods with a higher risk of analytic error.

  2. MODERN METHODS OF DESIGN AND ARRANGEMENT OF RAMMING PILES IN PUNCHED HOLES

    Directory of Open Access Journals (Sweden)

    ZOTSENKO N. L.

    2015-10-01

    Full Text Available Problem statement. Ramming piles in punched holes (RPPH differ of high degree of use of supporting capacity of base because of forming in it a compacted zone at the expense of displacement of soil in the volume rammer and compacted material of expansion. The method of their construction almost exclude excavation and formwork, reducing the consumption of concrete, metal, accelerates zero cycle compared to the foundations raised and excavation and immersion into the soil of precast elements. The expansion of the normative base, their design and construction should be for further implementation of of natural objects. The correctness of the geomechanical model of plane and spatial version of finite element method (FEM should be proved for the calculation of cooperative work of RPPH as part of grillages with base. The most effective kinds of equipment and technological schemes of construction of RPPH should be noticed. Conclusions. The paper presents the main regulations on the design and the arrangement RPPH, corresponding of construction norms of Ukraine. The results of experimental and theoretical studies conducted by the authors for over thirty years, and the experience of the use of these piles on the objects of civil engineering, industrial and agricultural construction made their base. The use of the elastoplastic model with the criterion of Mohr-Coulomb strength for designing of the system "grillage -RPPH- soil" was substantiated. The designing in plane and spatial problems of FEM is proved that in the distance between the axes of adjacent piles up to five diameters is a correct choice of a flat version and simplifying of calculating scheme to the conventional strip foundation. An improved. The method of calculating of RPPH as part of grillages ribbon, where as the width of the foundation was taken a diameter of the broadening of the pile, and the depth of its inception corresponds to the bottom of it. The supporting layer of base under the

  3. Sizing of Compression Coil Springs Gas Regulators Using Modern Methods CAD and CAE

    Directory of Open Access Journals (Sweden)

    Adelin Ionel Tuţă

    2010-10-01

    Full Text Available This paper presents a method for compression coil springs sizing by gas regulators composition, using CAD techniques (Computer Aided Design and CAE (Computer Aided Engineering. Sizing is to optimize the functioning of the regulators under dynamic industrial and house-hold. Gas regulator is a device that automatically and continuously adjusted to maintain pre-set limits on output gas pressure at varying flow and input pressure. The performances of the pressure regulators like automatic systems depend on their behaviour under dynamic opera-tion. Time constant optimization of pneumatic actuators, which drives gas regulators, leads to a better functioning under their dynamic.

  4. Foucault's method for measuring the speed of light with modern apparatus

    Science.gov (United States)

    Vörös, Zoltán; Weihs, Gregor

    2015-05-01

    In this paper, we introduce two simple and inexpensive, yet quite accurate versions of the well-known Foucault method for measuring the speed of light. In a compact footprint of just 20 cm by 270 cm with readily available laboratory items, a rotating mirror taken from a laser printer, and a webcam, we obtained c=296\\720+/- 3000 km s-1, and c=302\\295+/- 3000 km s-1, respectively, both within less than a per cent of the defined value. The experiment also prepares students for extracting data through image processing.

  5. Modern efficient methods of steel vertical oil tanks clean-up

    Directory of Open Access Journals (Sweden)

    Nekrasov Vladimir

    2016-01-01

    Full Text Available The legislative base of the Russian Federation operating in the field of operation of tanks and tank parks is considered, and consecutive stages of technological process of cleaning of vertical steel tanks from oil ground deposits are presented. In work shortcomings of existing most widespread electromechanical mixers are described when using a hydraulic method of removal and prevention of formation of ground deposits in tanks with oil and oil products. For the purpose of increase of efficiency, reliability and decrease in power consumption of washout of oil ground deposits in tanks the new design of system of funneled washout and prevention of formation of deposits is offered.

  6. Transition from the Lactational Amenorrhea Method to other modern family planning methods in rural Bangladesh: barrier analysis and implications for behavior change communication program intervention design.

    Science.gov (United States)

    Kouyaté, Robin Anthony; Ahmed, Salahuddin; Haver, Jaime; McKaig, Catharine; Akter, Nargis; Nash-Mercado, Angela; Baqui, Abdullah

    2015-06-01

    The timely transition from Lactational Amenorrhea Method (LAM)(2) to another modern family planning method contributes to healthy spacing of pregnancies by increasing the adoption of family planning during the first year postpartum. Yet, literature suggests challenges in completing a timely LAM transition. To guide program implementation in Bangladesh, this study identified factors influencing women's transition decisions. Eighty postpartum women, comprising 40 who transitioned from LAM(3) and 40 who did not,(4) participated. Half of each group participated in in-depth interviews to explore the decision-making process. All participants responded to a "Barrier Analysis" questionnaire to identify differences in eight behavioral determinants. More than half of transitioners switched to another modern method before or within the same month that LAM ended. Of the 18 transitioners who delayed,(5) 15 waited for menses to return. For non-transitioners, key barriers included waiting for menses to return, misconceptions on return to fertility, and perceived lack of familial support. The LAM transition can help women prevent unintended pregnancy during the first year postpartum. Increased emphasis on counseling women about the risk of pregnancy, and misconceptions about personal fertility patterns are critical for facilitating the transition. Strategies should also include interventions that train health workers and improve social support. Copyright © 2015. Published by Elsevier Ltd.

  7. Flowfield analysis of modern helicopter rotors in hover by Navier-Stokes method

    Science.gov (United States)

    Srinivasan, G. R.; Raghavan, V.; Duque, E. P. N.

    1991-01-01

    The viscous, three-dimensional, flowfields of UH60 and BERP rotors are calculated for lifting hover configurations using a Navier-Stokes computational fluid dynamics method with a view to understand the importance of planform effects on the airloads. In this method, the induced effects of the wake, including the interaction of tip vortices with successive blades, are captured as a part of the overall flowfield solution without prescribing any wake models. Numerical results in the form of surface pressures, hover performance parameters, surface skin friction and tip vortex patterns, and vortex wake trajectory are presented at two thrust conditions for UH60 and BERP rotors. Comparison of results for the UH60 model rotor show good agreement with experiments at moderate thrust conditions. Comparison of results with equivalent rectangular UH60 blade and BERP blade indicates that the BERP blade, with an unconventional planform, gives more thrust at the cost of more power and a reduced figure of merit. The high thrust conditions considered produce severe shock-induced flow separation for UH60 blade, while the BERP blade develops more thrust and minimal separation. The BERP blade produces a tighter tip vortex structure compared with the UH60 blade. These results and the discussion presented bring out the similarities and differences between the two rotors.

  8. Thimble microscope system

    Science.gov (United States)

    Kamal, Tahseen; Rubinstein, Jaden; Watkins, Rachel; Cen, Zijian; Kong, Gary; Lee, W. M.

    2016-12-01

    Wearable computing devices, e.g. Google Glass, Smart watch, embodies the new human design frontier, where technology interfaces seamlessly with human gestures. During examination of any subject in the field (clinic, surgery, agriculture, field survey, water collection), our sensory peripherals (touch and vision) often go hand-in-hand. The sensitivity and maneuverability of the human fingers are guided with tight distribution of biological nerve cells, which perform fine motor manipulation over a range of complex surfaces that is often out of sight. Our sight (or naked vision), on the other hand, is generally restricted to line of sight that is ill-suited to view around corner. Hence, conventional imaging methods are often resort to complex light guide designs (periscope, endoscopes etc) to navigate over obstructed surfaces. Using modular design strategies, we constructed a prototype miniature microscope system that is incorporated onto a wearable fixture (thimble). This unique platform allows users to maneuver around a sample and take high resolution microscopic images. In this paper, we provide an exposition of methods to achieve a thimble microscopy; microscope lens fabrication, thimble design, integration of miniature camera and liquid crystal display.

  9. [Surgical methods for delivery in modern obstetrics and their influence on maternal and infant health].

    Science.gov (United States)

    Kokhanevych, Ie V; Mitsoda, R M; Konoplianko, T V; Konoplianko, V V

    2000-03-01

    The article addresses issues of comparative characterization of deliveries involving surgery and impact thereof on the health of the mother and her child. Risk factors are identified that the mother and her child run in sectio cesarea, in application of obstetrical forceps, and in vacuum-extraction of the fetus. Cesarean section was found out to be the most acceptable mode of delivery in origination of organic and functional nervous system involvement in children but the most ill-chosen and unpropitious one in the mother, especially so in those groups at risk for bleeding, septic complications, and genital endometriosis. Among those surgical methods of delivery being the least traumatic to the mother are obstetrical forceps and vacuum-extraction of the fetus.

  10. Modern methods of drilling wells by large diameter bits and possible fields of application

    Energy Technology Data Exchange (ETDEWEB)

    Arnold, W

    1970-04-01

    For the needs of up-to-date mining in construction of shafts and mining installations, large diameter wells are often used. In the near future, application of this type of well will be of great importance in the oil industry for stimulation of oil and gas recovery by atomic explosion. Such wells can be used for mineral extraction from subsea and other accessible deposits. The presented state of drilling techniques and technology by large diameter bits is described and similarities and differences with deep-well drilling are pointed out. Some economical data indicate the advantage of drilling by large-diameter bits in comparison with standard methods of construction of shafts and mining installations.

  11. Pedagogical terms of forming of healthy method of life of modern pupils

    Directory of Open Access Journals (Sweden)

    Odarchenko V.I.

    2012-10-01

    Full Text Available The questions of conditioning forming of healthy method of life of pupils of general educational educational establishments are probed. In an experiment 156 pupils took part in age from 6 to 17 years. It is set that the characteristic feature of bodily condition of health of pupils is a result of the protracted unfavorable influence of socio-economic, ecological and pedagogical factors. An idea speaks out, that search of the new going near organization of an educational educate process at school it is necessary to send educations to humanizing. It will provide creation of optimum terms for spiritual growth of personality, valuable realization of psychophysical possibilities, maintainance and strengthening of health. It is well-proven that realization of the personality oriented approach taking into account basic valeological principles positively influences on the process of education of responsible attitude toward an own health as to the greatest individual and public value.

  12. Modern methods of eddy-current testing for avoiding material mistakes

    International Nuclear Information System (INIS)

    Baumgartner, H.

    1987-01-01

    The conservation of raw materials and energy as a general goal in all fields is the reason why also in mechanical engineering and motor vehicle engineering, cross-sectional areas are reduced. The advantages thus obtained, - lower weight and lower manufacturing cost-, on the other hand require special core on the part of the manufacturer who has to enhance the testing activities in order to assure the appropriate structural conditions, also in mass production. Any wrong thermal treatment, or use of wrong material which remain undetected, may have disastrous effects. The eddy-current testing method now offers a mature procedure of quality assurance and is shown to be highly reliable with the attached computing equipment, guaranteeing 100 p.c. testing of manufactured goods. (orig.) [de

  13. Modern Breeding Methods for Improving Protein Quality and Quantity in Plants

    Energy Technology Data Exchange (ETDEWEB)

    Dumanovic, J.; Ehrenberg, L. [Institute for the Application of Nuclear Energy in Agriculture, Veterinary Medicine and Forestry, Belgrade, Yugoslavia (Serbia)

    1968-07-01

    Against the background of the world's urgent need for increased protein production and for an improved quality of vegetable proteins, the ability of plant breeding to contribute to this need is discussed. With examples especially from maize and wheat, existing variations in protein content and protein composition are surveyed, together with the interdependence of these characteristics and their co-variation with the yield. It is shown that plant breeding has a great potential for improving the world's food situation. It is also shown that more rapid achievements are possible than is generally considered to be characteristic of plant-breeding techniques. Special emphasis is stressed on: (a) The capacity of mutation breeding, alone and in conjunction with other methods, to contribute to an increased production of high quality protein; (b) The necessity for the success of programmes whereby fast, cheap, and if possible non-destructive analytical procedures are developed to determine protein and amino acids; (c) The importance of the close collaboration of plant breeders with specialists in related subjects such as soil fertilization, physiology and nutrition, food technology, and biochemistry; (d) The importance of international co-operation and co-ordination. (author)

  14. Men's knowledge and spousal communication about modern family planning methods in Ethiopia.

    Science.gov (United States)

    Berhane, Adugnaw; Biadgilign, Sibhatu; Amberbir, Alemayehu; Morankar, Sudhakar; Berhane, Alemayehu; Deribe, Kebede

    2011-12-01

    This study attempted to determine knowledge, approval and communication about family planning methods among married men in Ethiopia. A cross-sectional study was conducted among a representative sample of 738 married males in Amhara Region. All 738 (100%) of the respondents had heard of family planning. About 558 (75.6%) mentioned the importance of using contraceptives for birth spacing and 457 (61.9%) to limit birth. Four hundred and forty-five (60.3%) of participants had ever discussed family planning with their wives. Thirty-three (33.0%) of the respondents reported that they were the sole decision makers in their families. About 597 (80.9%) approved the use of contraceptives. However, some participants did not discuss and approve family planning with their partner. This recalled an intensive effort has been taken by the concerned body to reach the country's targeted family planning coverage by involving men in reproductive health endeavor to enhance the discussion and agreement about family planning usage.

  15. Modern contact investigation methods for enhancing tuberculosis control in Aboriginal communities

    Directory of Open Access Journals (Sweden)

    Victoria J. Cook

    2012-05-01

    Full Text Available The Aboriginal communities in Canada are challenged by a disproportionate burden of TB infection and disease. Contact investigation (CI guidelines exist but these strategies do not take into account the unique social structure of different populations. Because of the limitations of traditional CI, new approaches are under investigation and include the use of social network analysis, geographic information systems and genomics, in addition to the widespread use of genotyping to better understand TB transmission. Guidelines for the routine use of network methods and other novel methodologies for TB CI and outbreak investigation do not exist despite the gathering evidence that these approaches can positively impact TB control efforts, even in Aboriginal communities. The feasibility and efficacy of these novel approaches to CI in Aboriginal communities requires further investigation. The successful integration of these novel methodologies will require community involvement, capacity building and ongoing support at every level. The outcome will not only be the systematic collection, analysis, and interpretation of CI data in high-burden communities to assess transmission but the prioritization of contacts who are candidates for treatment of LTBI which will break the cycle of transmission. Ultimately, the measure of success will be a clear and sustained decline in TB incidence in Aboriginal communities.

  16. Analysis of rail welding methods for mine rail access with the use of modern technologies

    Science.gov (United States)

    Usoltsev, A. A.; Shevchenko, R. A.; Kozyrev, N. A.; Kriukov, R. E.; Shishkin, P. E.

    2017-09-01

    Welded joint zones are weak sections of the railway track for all traffic cases (in the case of high-speed traffic and heavy traffic). In the paper advantages and disadvantages of the basic ways of rails welding, which are widely used today, are considered: electrocontact and aluminothermic. Carefully selected mode of differentially thermally strengthened rails string will allow the process of correction after heat treatment to be minimized and internal residual compressive stresses to be kept. Particular attention should be paid to the method of rails welding, in which after rails welding during their cooling it is offered to perform quasi-isothermal exposure in the temperature range of fine structure formation by passing pulses of alternating electric current through the welded joint maintaining this temperature until the end of the transformation. The use of quasi-isothermal exposure at a temperature of 600 - 650 °C makes it possible to obtain a finely dispersed structure of the welded seam of rails without additional heat treatment.

  17. Simple method for sub-diffraction resolution imaging of cellular structures on standard confocal microscopes by three-photon absorption of quantum dots.

    Directory of Open Access Journals (Sweden)

    Anje Sporbert

    Full Text Available This study describes a simple technique that improves a recently developed 3D sub-diffraction imaging method based on three-photon absorption of commercially available quantum dots. The method combines imaging of biological samples via tri-exciton generation in quantum dots with deconvolution and spectral multiplexing, resulting in a novel approach for multi-color imaging of even thick biological samples at a 1.4 to 1.9-fold better spatial resolution. This approach is realized on a conventional confocal microscope equipped with standard continuous-wave lasers. We demonstrate the potential of multi-color tri-exciton imaging of quantum dots combined with deconvolution on viral vesicles in lentivirally transduced cells as well as intermediate filaments in three-dimensional clusters of mouse-derived neural stem cells (neurospheres and dense microtubuli arrays in myotubes formed by stacks of differentiated C2C12 myoblasts.

  18. Development of an environment-insensitive PWR radial reflector model applicable to modern nodal reactor analysis method

    International Nuclear Information System (INIS)

    Mueller, E.M.

    1989-05-01

    This research is concerned with the development and analysis of methods for generating equivalent nodal diffusion parameters for the radial reflector of a PWR. The requirement that the equivalent reflector data be insensitive to changing core conditions is set as a principle objective. Hence, the environment dependence of the currently most reputable nodal reflector models, almost all of which are based on the nodal equivalence theory homgenization methods of Koebke and Smith, is investigated in detail. For this purpose, a special 1-D nodal equivalence theory reflector model, called the NGET model, is developed and used in 1-D and 2-D numerical experiments. The results demonstrate that these modern radial reflector models exhibit sufficient sensitivity to core conditions to warrant the development of alternative models. A new 1-D nodal reflector model, which is based on a novel combination of the nodal equivalence theory and the response matrix homogenization methods, is developed. Numerical results varify that this homogenized baffle/reflector model, which is called the NGET-RM model, is highly insensitive to changing core conditions. It is also shown that the NGET-RM model is not inferior to any of the existing 1-D nodal reflector models and that it has features which makes it an attractive alternative model for multi-dimensional reactor analysis. 61 refs., 40 figs., 36 tabs

  19. Application of Modern Experimental Technique to Solve Morphological Complexity in Plants Taxonomy

    Directory of Open Access Journals (Sweden)

    SURANTO

    2000-07-01

    Full Text Available Modern taxonomy has two approaches, i.e. classical and experimental taxonomy. Classical taxonomy uses morphological characters, while experimental taxonomy uses broader methods including chemistry, physics and mathematics, in the form of laboratory data that are revealed together with the progress of optical technique (microscope, chemistry methods (chromatography, electrophoresis, etc. Modern taxonomy tends to use series of interrelated data. More data used would result in more validity and give better clarification of taxonomic status. A lot of modern taxonomic data such as palynology, cytotaxonomy (cytology, chemical constituent (chemotaxonomy, isozyme and DNA sequencing were used recently.

  20. The use of modern methods for complex studies of the hydrotechnical structures of the Barents Sea region

    Directory of Open Access Journals (Sweden)

    Mel'nikov N. N

    2017-03-01

    Full Text Available The Barents region hydrotechnical structures (HTS as part of the bulk earth dams and levees tailings of mining enterprises in terms of requirements of the responsible entities have been considered. The brief review of emergencies and accidents of HTS with an analysis of their causes and geo-ecological consequences has been fulfilled. The necessity and urgency of the application of modern techniques for comprehensive research and monitoring of the HTS state have been shown: geo-fluid mechanics computer modeling, subsurface georadar sensing, GPS geodetic measurements, optical and radar satellite imagery. Joint use of GPR and satellite imagery in combination with traditional engineering-geological, hydro-geological and geodetic studies allows obtaining a more complete picture of the HTS state taking into account local and regional geological and fluid dynamic processes. The system structure of HTS complex researches which creates a scientific and technical basis for researching the geologic-geophysical environment, shifts, deformations and power influence has been developed. This allows to reveal the hidden filtration and deformation zones in HTS at early stages of their formation and in due time to make the administrative decision on prevention and localization of any emergency. Application of modern methods for HTS complex researches will allow to receive operational information on their state, parametrical sizes of volume, angular and linear deformations and movements, intensity of natural and technogenic influence. The obtained data have to be integrated in the "Database and Parameters" geoportal by means of which their logical processing and comparison to standard and extreme values has to be carried out. On this basis expert assessment of the current and expected state of HTS is carried out and the operating decisions including on development, in case of need, of preventive and protective measures are made

  1. Problems in creation of modern air inlet filters of power gas turbine plants in Russia and methods of their solving

    Science.gov (United States)

    Mikhaylov, V. E.; Khomenok, L. A.; Sherapov, V. V.

    2016-08-01

    The main problems in creation and operation of modern air inlet paths of gas turbine plants installed as part of combined-cycle plants in Russia are presented. It is noted that design features of air inlet filters shall be formed at the stage of the technical assignment not only considering the requirements of gas turbine plant manufacturer but also climatic conditions, local atmospheric air dustiness, and a number of other factors. The recommendations on completing of filtration system for air inlet filter of power gas turbine plants depending on the facility location are given, specific defects in design and experience in operation of imported air inlet paths are analyzed, and influence of cycle air preparation quality for gas turbine plant on value of operating expenses and cost of repair works is noted. Air treatment equipment of various manufacturers, influence of aerodynamic characteristics on operation of air inlet filters, features of filtration system operation, anti-icing system, weather canopies, and other elements of air inlet paths are considered. It is shown that nonuniformity of air flow velocity fields in clean air chamber has a negative effect on capacity and aerodynamic resistance of air inlet filter. Besides, the necessity in installation of a sufficient number of differential pressure transmitters allowing controlling state of each treatment stage not being limited to one measurement of total differential pressure in the filtration system is noted in the article. According to the results of the analysis trends and methods for modernization of available equipment for air inlet path, the importance of creation and implementation of new technologies for manufacturing of filtering elements on sites of Russia within the limits of import substitution are given, and measures on reliability improvement and energy efficiency for air inlet filter are considered.

  2. ELECTRON MICROSCOPIC INVESTIGATION OF YTTRIUM ALUMINUM GARNET POWDERS Y3AL5O12, SYNTHESIZED BY SOL–GEL METHOD

    OpenAIRE

    A. E. Baranchikov; V. A. Maslov; S. V. Shcherbakov; V. A. Usachyov; N. E. Kononenko; P. P. Fedorov; K. V. Dukelskiy

    2015-01-01

    Subject of Study. The paper presents results of characterization for neodymium doped yttrium aluminum garnet nanopowders - YAG:Nd3+ by the method of scanning electronic microscopy. Method. Synthesis of YAG:Nd3+ was carried out by sol-gel method from nitrate or acetate - nitrate solutions with addition of some organic compounds and ammonia as well. Such substances were used as the source ones: oxides of neodymium and yttrium with the content of the basic substance equal to 99.999 %; organic co...

  3. TITRATION METHOD OF AB0 ANTIBODIES WITH THE USE OF MODERN GEL TECHNOLOGY IN AB0-INCOMPATIBLE TRANSPLANTATION

    Directory of Open Access Journals (Sweden)

    A. K. Porunova

    2014-01-01

    Full Text Available It is shown that developed method of titrating AB0 antibodies allows defi ning the titer of the investigational antibodies more precisely on 1–3 dilution of serum compared to the prototype method (titration method of antibodiesin saline medium on the plane. It is more obvious as it excludes hardly interpretable results due to the possibility of conducting visual assessment of agglutination reaction in the gel card thick column and requires less time foranalysis. The results can be saved for comparison with the results of further research. That is not possible under prototype titration method. Aim: our aim is to create a laboratory technique that can accurately, reliably and clearly produce titration of AB0 system antibodies, including in patients with low initial concentration of agglutinins in the blood; a technique more economical in terms of spending serum and that takes less time.Materials and methods: those modes were empirically chosen which allow titration of AB0 system agglutinins using gel technology based micro typing; to titer group antibodies 1640 serum assays of recipients in AB0-incompatibletransplantation were analyzed.The result of the use of specially developed method in organ transplantation from incompatible blood donors consists in enhancing accuracy, sensitivity of natural, complete and incomplete AB0 system immune antibodies titration, in its clarity, using of blood micro-doses for earlier detection of sensitizing of the patient, which is especially important in Pediatrics. Conclusion: the developed procedure of AB0-antibodies’ titration using modern gel technology makes possible a more precise monitoring of the titer of antibodies that is necessary to predict the graft rejection risk, to select the Protocol of preoperative preparation and postoperative management of patients, to assess the effectiveness of therapy in patients for whom it is diffi cult to fi nd a compatible blood type donor, and for whom today AB

  4. On microscopic theory of radiative nuclear reaction characteristics

    Energy Technology Data Exchange (ETDEWEB)

    Kamerdzhiev, S. P. [National Research Centre “Kurchatov Institute” (Russian Federation); Achakovskiy, O. I., E-mail: oachakovskiy@ippe.ru; Avdeenkov, A. V. [Institute for Physics and Power Engineering (Russian Federation); Goriely, S. [Institut d’Astronomie et d’Astrophysique (Belgium)

    2016-07-15

    A survey of some results in the modern microscopic theory of properties of nuclear reactions with gamma rays is given. First of all, we discuss the impact of Phonon Coupling (PC) on the Photon Strength Function (PSF) because it represents the most natural physical source of additional strength found for Sn isotopes in recent experiments that could not be explained within the standard HFB + QRPA approach. The self-consistent version of the Extended Theory of Finite Fermi Systems in the Quasiparticle Time Blocking Approximation is applied. It uses the HFB mean field and includes both the QRPA and PC effects on the basis of the SLy4 Skyrme force. With our microscopic E1 PSFs, the following properties have been calculated for many stable and unstable even–even semi-magic Sn and Ni isotopes as well as for double-magic {sup 132}Sn and {sup 208}Pb using the reaction codes EMPIRE and TALYS with several Nuclear Level Density (NLD) models: (1) the neutron capture cross sections; (2) the corresponding neutron capture gamma spectra; (3) the average radiative widths of neutron resonances. In all the properties considered, the PC contribution turned out to be significant, as compared with the standard QRPA one, and necessary to explain the available experimental data. The results with the phenomenological so-called generalized superfluid NLD model turned out to be worse, on the whole, than those obtained with the microscopic HFB + combinatorial NLD model. The very topical question about the M1 resonance contribution to PSFs is also discussed.Finally, we also discuss the modern microscopic NLD models based on the self-consistent HFB method and show their relevance to explain the experimental data as compared with the phenomenological models. The use of these self-consistent microscopic approaches is of particular relevance for nuclear astrophysics, but also for the study of double-magic nuclei.

  5. Comparison of four DNA extraction methods for the detection of Mycobacterium leprae from Ziehl-Neelsen-stained microscopic slides.

    Science.gov (United States)

    Ruiz-Fuentes, Jenny Laura; Díaz, Alexis; Entenza, Anayma Elena; Frión, Yahima; Suárez, Odelaisy; Torres, Pedro; de Armas, Yaxsier; Acosta, Lucrecia

    2015-12-01

    The diagnosis of leprosy has been a challenge due to the low sensibility of the conventional methods and the impossibility of culturing the causative organism. In this study, four methods for Mycobacterium leprae nucleic-acid extraction from Ziehl-Neelsen-stained slides (ZNS slides) were compared: Phenol/chloroform, Chelex 100 resin, and two commercial kits (Wizard Genomic DNA Purification Kit and QIAamp DNA Mini Kit). DNA was extracted from four groups of slides: a high-codification-slide group (bacteriological index [BI]⩾4), a low-codification-slide group (BI=1), a negative-slide group (BI=0), and a negative-control-slide group (BI=0). Quality DNA was evidenced by the amplification of specific repetitive element present in M. leprae genomic DNA (RLEP) using a nested polymerase chain reaction. This is the first report comparing four different extraction methods for obtaining M. leprae DNA from ZNS slides in Cuban patients, and applied in molecular diagnosis. Good-quality DNA and positive amplification were detected in the high-codification-slide group with the four methods, while from the low-codification-slide group only the QIAGEN and phenol-chloroform methods obtained amplification of M. leprae. In the negative-slide group, only the QIAGEN method was able to obtain DNA with sufficient quality for positive amplification of the RLEP region. No amplification was observed in the negative-control-slide group by any method. Patients with ZNS negative slides can still transmit the infection, and molecular methods can help identify and treat them, interrupting the chain of transmission and preventing the onset of disabilities. The ZNS slides can be sent easily to reference laboratories for later molecular analysis that can be useful not only to improve the diagnosis, but also for the application of other molecular techniques. Copyright © 2015 Asian-African Society for Mycobacteriology. Published by Elsevier Ltd. All rights reserved.

  6. A fully automated calibration method for an optical see-through head-mounted operating microscope with variable zoom and focus.

    Science.gov (United States)

    Figl, Michael; Ede, Christopher; Hummel, Johann; Wanschitz, Felix; Ewers, Rolf; Bergmann, Helmar; Birkfellner, Wolfgang

    2005-11-01

    Ever since the development of the first applications in image-guided therapy (IGT), the use of head-mounted displays (HMDs) was considered an important extension of existing IGT technologies. Several approaches to utilizing HMDs and modified medical devices for augmented reality (AR) visualization were implemented. These approaches include video-see through systems, semitransparent mirrors, modified endoscopes, and modified operating microscopes. Common to all these devices is the fact that a precise calibration between the display and three-dimensional coordinates in the patient's frame of reference is compulsory. In optical see-through devices based on complex optical systems such as operating microscopes or operating binoculars-as in the case of the system presented in this paper-this procedure can become increasingly difficult since precise camera calibration for every focus and zoom position is required. We present a method for fully automatic calibration of the operating binocular Varioscope M5 AR for the full range of zoom and focus settings available. Our method uses a special calibration pattern, a linear guide driven by a stepping motor, and special calibration software. The overlay error in the calibration plane was found to be 0.14-0.91 mm, which is less than 1% of the field of view. Using the motorized calibration rig as presented in the paper, we were also able to assess the dynamic latency when viewing augmentation graphics on a mobile target; spatial displacement due to latency was found to be in the range of 1.1-2.8 mm maximum, the disparity between the true object and its computed overlay represented latency of 0.1 s. We conclude that the automatic calibration method presented in this paper is sufficient in terms of accuracy and time requirements for standard uses of optical see-through systems in a clinical environment.

  7. Calibration of atomic force microscope cantilevers using standard and inverted static methods assisted by FIB-milled spatial markers

    International Nuclear Information System (INIS)

    Slattery, Ashley D; Blanch, Adam J; Quinton, Jamie S; Gibson, Christopher T

    2013-01-01

    Static methods to determine the spring constant of AFM cantilevers have been widely used in the scientific community since the importance of such calibration techniques was established nearly 20 years ago. The most commonly used static techniques involve loading a trial cantilever with a known force by pressing it against a pre-calibrated standard or reference cantilever. These reference cantilever methods have a number of sources of uncertainty, which include the uncertainty in the measured spring constant of the standard cantilever, the exact position of the loading point on the reference cantilever and how closely the spring constant of the trial and reference cantilever match. We present a technique that enables users to minimize these uncertainties by creating spatial markers on reference cantilevers using a focused ion beam (FIB). We demonstrate that by combining FIB spatial markers with an inverted reference cantilever method, AFM cantilevers can be accurately calibrated without the tip of the test cantilever contacting a surface. This work also demonstrates that for V-shaped cantilevers it is possible to determine the precise loading position by AFM imaging the section of the cantilever where the two arms join. Removing tip-to-surface contact in both the reference cantilever method and sensitivity calibration is a significant improvement, since this is an important consideration for AFM users that require the imaging tip to remain in pristine condition before commencing measurements. Uncertainties of between 5 and 10% are routinely achievable with these methods. (paper)

  8. Microscopic approach to nuclear anharmonicities

    International Nuclear Information System (INIS)

    Matsuo, Masayuki; Shimizu, Yoshifumi; Matsuyanagi, Kenichi

    1985-01-01

    Present status of microscopic study of nuclear anharmonicity phenomena is reviewed from the viewpoint of the time-dependent Hartree-Bogoliubov approach. Both classical- and quantum-mechanical aspects of this approach are discussed. The Bohr-Mottelson-type collective Hamiltonian for anharmonic gamma vibrations is microscopically derived by means of the self-consistent-collective-coordinate method, and applied to the problem of two-phonon states of 168 Er. (orig.)

  9. Deuteron microscopic optical model potential

    International Nuclear Information System (INIS)

    Guo Hairui; Han Yinlu; Shen Qingbiao; Xu Yongli

    2010-01-01

    A deuteron microscopic optical model potential is obtained by the Green function method through nuclear-matter approximation and local-density approximation based on the effective Skyrme interaction. The microscopic optical model potential is used to calculate the deuteron reaction cross sections and the elastic scattering angular distributions for some target nuclei in the mass range 6≤A≤208 with incident deuteron energies up to 200 MeV. The calculated results are compared with the experimental data.

  10. Biopsy Diagnosis of Oral Carcinoma by the Combination of Morphological and Spectral Methods Based on Embedded Relay Lens Microscopic Hyperspectral Imaging System.

    Science.gov (United States)

    Ou-Yang, Mang; Hsieh, Yao-Fang; Lee, Cheng-Chung

    Cytopathological examination through biopsy is very important for carcinoma detection. The embedded relay lens microscopic hyperspectral imaging system (ERL-MHIS) provides a morphological image of a biopsy sample and the spectrum of each pixel in the image simultaneously. Based on the ERL-MHIS, this work develops morphological and spectral methods to diagnose oral carcinoma biopsy. In morphological discrimination, the fractal dimension method is applied to differentiate between normal and abnormal tissues. In spectral identification, normal and cancerous cells are distinguished using five methods. However, the spectra of normal and cancerous cells vary with patient. The diagnostic performances of the five methods are thus not ideal. Hence, the proposed cocktail approach is used to determine the effectiveness of the spectral methods in correlating with the sampling conditions. And then we use a combination of effective spectral methods according to the sample conditions for diagnosing a sample. A total of 68 biopsies from 34 patients are analyzed using the ERL-MHIS. The results demonstrate a sensitivity of 90 ± 4.53 % and a specificity of 87.8 ± 5.21 %. Furthermore, in our survey, this system is the first time utilized to study oral carcinoma biopsies.

  11. A simple and inclusive method to determine the habit plane in transmission electron microscope based on accurate measurement of foil thickness

    International Nuclear Information System (INIS)

    Qiu, Dong; Zhang, Mingxing

    2014-01-01

    A simple and inclusive method is proposed for accurate determination of the habit plane between bicrystals in transmission electron microscope. Whilst this method can be regarded as a variant of surface trace analysis, the major innovation lies in the improved accuracy and efficiency of foil thickness measurement, which involves a simple tilt of the thin foil about a permanent tilting axis of the specimen holder, rather than cumbersome tilt about the surface trace of the habit plane. Experimental study has been done to validate this proposed method in determining the habit plane between lamellar α 2 plates and γ matrix in a Ti–Al–Nb alloy. Both high accuracy (± 1°) and high precision (± 1°) have been achieved by using the new method. The source of the experimental errors as well as the applicability of this method is discussed. Some tips to minimise the experimental errors are also suggested. - Highlights: • An improved algorithm is formulated to measure the foil thickness. • Habit plane can be determined with a single tilt holder based on the new algorithm. • Better accuracy and precision within ± 1° are achievable using the proposed method. • The data for multi-facet determination can be collected simultaneously

  12. Modern Methods of Contraception

    African Journals Online (AJOL)

    Rubber products are used extensively in the production of condoms, caps ... in oral contraceptives since 1960 have been in the direction of loweling the dose. ... no mid cycle increase in oestrogen, follicular stimulating hor- mone (FSH), and ...

  13. Investigation the effect of porosity on corrosion of macroporous silicon in 1.0 M sodium hydroxide solution using weight loss measurements, electrochemical methods and scanning electron microscope

    International Nuclear Information System (INIS)

    Lai, Chuan; Xiang, Zhen

    2015-01-01

    Highlights: • The dissolution of silicon wafers conforms Faraday’s laws of electrolysis. • The porosity effect on macroporous silicon corrosion was investigated. • The corrosion rate increase linearly with porosity increasing. • The porosity effect on activation parameters was obtained. - Abstract: In this study, the macroporous silicon has been fabricated by electrochemical anodization. The dissolution of n-type silicon wafers in etching solution conforms Faraday’s laws of electrolysis. The fabricated macroporous silicon with different porosity corrosion in 1.0 M NaOH was systemically investigated by weight loss measurements, electrochemical methods and scanning electron microscope. Results show that with the porosity increasing, the corrosion rate of macroporous silicon in 1.0 M NaOH increases linearly. In addition, the increase of corrosion rate of macroporous silicon with relative higher porosity was determined by the pre-exponential factor.

  14. A computationally efficient P_1 radiation model for modern combustion systems utilizing pre-conditioned conjugate gradient methods

    International Nuclear Information System (INIS)

    Krishnamoorthy, Gautham

    2017-01-01

    Highlights: • The P_1 radiation model was interfaced with high performance linear solvers. • Pre-conditioned conjugate gradient (PC CG) method improved convergence by 50% • PC CG was more than 30 times faster than classical iterative methods. • The time to solution scaled linearly with increase in problem size employing PC CG. • Employing WSGGM with P_1 model compared reasonably well against benchmark data. - Abstract: The iterative convergence of the P_1 radiation model can be slow in optically thin scenarios when employing classical iterative methods. In order to remedy this shortcoming, an in-house P_1 radiation model was interfaced with high performance, scalable, linear solver libraries. Next, the accuracies of P_1 radiation model calculations was assessed by comparing its predictions against discrete ordinates (DO) model calculations for prototypical problems representative of modern combustion systems. Corresponding benchmark results were also included for comparison. Utilizing Pre-Conditioners (PC) to the Conjugate Gradients (CG) method, the convergence time of the P_1 radiation model reduced by a factor of 30 for modest problem sizes and a factor of 70 for larger sized problems when compared against classical Gauss Seidel sweeps. Further, PC provided 50% computational savings compared to employing CG in a standalone mode. The P_1 model calculation times were about 25–30% of the DO model calculation time. The time to solution also scaled linearly with an increase in problem size. The weighted sum of gray gases model employed in this study in conjunction with the P_1 model provided good agreement against benchmark data with L_2 error norms (defined relative to corresponding DO calculations) improving when isotropic intensities were prevalent.

  15. A method for obturating microscopic ports in parts submitted to stresses, e.g. heat-exchangers

    International Nuclear Information System (INIS)

    Halstead, W.D.

    1975-01-01

    The invention relates to the obturation of cracks in metal-parts. It refers to a method for obturating the micropores of a member adapted to be submitted to stresses, said method being characterized in that it comprises the steps of exposing one surface of said member to a mixture of nickel-carbonyl and hydrogen sulfide with an inert gaseous carrier, and exposing the member other surface to air or nitrogen with oxygen or steam, the gases being at substantially the same pressure and at a temperature of from 290 to 330 deg K. This can be applied to the obturation of micropores in the heat exchangers of sodium cooled nuclear reactor [fr

  16. Relative diversity and community structure analysis of rumen protozoa according to T-RFLP and microscopic methods.

    Science.gov (United States)

    Tymensen, Lisa; Barkley, Cindy; McAllister, Tim A

    2012-01-01

    Protozoa are common inhabitants of the rumen where they play roles in host nutrition and methanogenesis. Knowledge of how changes in the composition of protozoa communities affect these processes is limited in part due to a lack of efficient methods for protozoa community analysis. In this study, a terminal-restriction fragment length polymorphism (T-RFLP) assay targeting the 18S rRNA gene was developed for comparative analysis of rumen protozoa communities. Comparison of diversity and structure of protozoa communities from hay-fed versus silage/grain-fed cattle via T-RFLP analysis yielded similar overall results to microscopy analysis. According to both methods, Entodinium spp. were more abundant in the silage/grain-fed cattle and protozoa diversity (as calculated using the Shannon index) was higher for the hay-fed cattle due to greater species evenness. Type B protozoa were more prevalent in the hay-fed cattle, whereas Type A protozoa were more prevalent in the silage/grain-fed cattle. Analysis of similarity (ANOSIM) indicated that the protozoa communities from hay-fed and silage/grain-fed cattle were different, and multivariate analysis indicated that pen mates (i.e., cattle fed the same diet and housed together) tended to have similar protozoa communities types. In summary, we present a T-RFLP method for analyzing rumen protozoa communities which complements traditional microscopy approaches but has the advantage of being amenable to high-throughput. Copyright © 2011. Published by Elsevier B.V.

  17. Predictors of modern contraceptive methods use among married women of reproductive age groups in Western Ethiopia: a community based cross-sectional study.

    Science.gov (United States)

    Tekelab, Tesfalidet; Melka, Alemu Sufa; Wirtu, Desalegn

    2015-07-17

    In Ethiopia, the prevalence of modern contraceptive use is very low (27 %) and the percentage of those with unmet needs for family planning is 25 %. The current study identified factors associated with the utilization of modern contraceptive methods among married women in Western Ethiopia. A community based, cross-sectional study was employed from April 10 to April 25, 2014, among married women of reproductive age in Nekemte Town. A multi-stage sampling procedure was used to select 1003 study participants. A pretested structured questionnaire was used to collect data, and data collectors who had completed high school were involved in the data collection process. A bivariate, multivariable logistic regression model was fit, and statistical significance was determined with a 95% confidence level. The overall utilization rate of modern contraceptives in this study was 71.9%. The most common form of modern contraceptives used was injectable (60.3%). Age (AOR = 2.00, 95 % CI = 1.35-2.98), women's educational level (AOR = 2.50, 95 % CI = 1.62-3.84), monthly income (AOR = 2.26, 95 % CI = 1.24-4.10), respondent's fertility (AOR = 2.60, 95 % CI = 1.48-4.56), fertility-related decision (AOR = 3.70, 95 % CI = 2.45-5.58), and having radio (AOR = 1.93, 95 % CI = 1.37-2.71) showed significant positive associations with the utilization of modern contraceptive methods. The findings showed that women's empowerment, fertility-related discussions among couples, and the availability of the media were important factors that influenced the use of modern contraceptives. Thus, policymakers and implementers should work on those factors to increase the utilization of modern contraceptive methods.

  18. Shlaer-Mellor object-oriented analysis and recursive design, an effective modern software development method for development of computing systems for a large physics detector

    International Nuclear Information System (INIS)

    Kozlowski, T.; Carey, T.A.; Maguire, C.F.

    1995-01-01

    After evaluation of several modern object-oriented methods for development of the computing systems for the PHENIX detector at RHIC, we selected the Shlaer-Mellor Object-Oriented Analysis and Recursive Design method as the most appropriate for the needs and development environment of a large nuclear or high energy physics detector. This paper discusses our specific needs and environment, our method selection criteria, and major features and components of the Shlaer-Mellor method

  19. An accuracy improvement method for the topology measurement of an atomic force microscope using a 2D wavelet transform.

    Science.gov (United States)

    Yoon, Yeomin; Noh, Suwoo; Jeong, Jiseong; Park, Kyihwan

    2018-05-01

    The topology image is constructed from the 2D matrix (XY directions) of heights Z captured from the force-feedback loop controller. For small height variations, nonlinear effects such as hysteresis or creep of the PZT-driven Z nano scanner can be neglected and its calibration is quite straightforward. For large height variations, the linear approximation of the PZT-driven Z nano scanner fail and nonlinear behaviors must be considered because this would cause inaccuracies in the measurement image. In order to avoid such inaccuracies, an additional strain gauge sensor is used to directly measure displacement of the PZT-driven Z nano scanner. However, this approach also has a disadvantage in its relatively low precision. In order to obtain high precision data with good linearity, we propose a method of overcoming the low precision problem of the strain gauge while its feature of good linearity is maintained. We expect that the topology image obtained from the strain gauge sensor showing significant noise at high frequencies. On the other hand, the topology image obtained from the controller output showing low noise at high frequencies. If the low and high frequency signals are separable from both topology images, the image can be constructed so that it is represented with high accuracy and low noise. In order to separate the low frequencies from high frequencies, a 2D Haar wavelet transform is used. Our proposed method use the 2D wavelet transform for obtaining good linearity from strain gauge sensor and good precision from controller output. The advantages of the proposed method are experimentally validated by using topology images. Copyright © 2018 Elsevier B.V. All rights reserved.

  20. Early quantitative method for measuring germination in non-green spores of Dryopteris paleacea using an epifluorescence-microscope technique

    Science.gov (United States)

    Scheuerlein, R.; Wayne, R.; Roux, S. J.

    1988-01-01

    A method is described to determine germination by blue-light excited red fluorescence in the positively photoblastic spores of Dryopteris paleacea Sw. This fluorescence is due to chlorophyll as evidenced from 1) a fluorescence-emission spectrum in vivo, where a bright fluorescence around 675 nm is obtained only in red light (R)-irradiated spores and 2) in vitro measurements with acetone extracts prepared from homogenized spores. Significant amounts of chlorophyll can be found only in R-treated spores; this chlorophyll exhibits an emission band around 668 nm, when irradiated with 430 nm light at 21 degrees C. Compared to other criteria for germination, such as swelling of the cell, coat splitting, greening, and rhizoid formation, which require longer periods after induction for their expression, chlorophyll fluorescence can be used to quantify germination after two days. This result is confirmed by fluence-response curves for R-induced spore germination; the same relationship between applied R and germination is obtained by the evaluation with the epifluorescence method 2 days after the light treatment as compared with the evaluation with bright-field microscopy 5 days after the inducing R. Using this technique we show for the first time that Ca2+ contributes to the signal-transduction chain in phytochrome-mediated chlorophyll synthesis in spores of Dryopteris paleacea.

  1. Transmission positron microscopes

    International Nuclear Information System (INIS)

    Doyama, Masao; Kogure, Yoshiaki; Inoue, Miyoshi; Kurihara, Toshikazu; Yoshiie, Toshimasa; Oshima, Ryuichiro; Matsuya, Miyuki

    2006-01-01

    Immediate and near-future plans for transmission positron microscopes being built at KEK, Tsukuba, Japan, are described. The characteristic feature of this project is remolding a commercial electron microscope to a positron microscope. A point source of electrons kept at a negative high voltage is changed to a point source of positrons kept at a high positive voltage. Positional resolution of transmission microscopes should be theoretically the same as electron microscopes. Positron microscopes utilizing trapping of positrons have always positional ambiguity due to the diffusion of positrons

  2. Atherosclerosis in Watanabe heritable hyperlipidaemic rabbits. Evaluation by macroscopic, microscopic and biochemical methods and comparison of atherosclerosis variables

    DEFF Research Database (Denmark)

    Hansen, B F; Mortensen, A; Hansen, J F

    1994-01-01

    estimation of aortic atherosclerosis extent and by biochemical analysis of aortic cholesterol content. No noteworthy atherosclerosis was demonstrated within 19 months in heterozygous rabbits. In homozygous rabbits, atherosclerotic lesions were seen from the age of 4 months and progressed with age. All 19......-month-old rabbits had severe atherosclerotic disease. As much as 64% of the variation in atherosclerosis extent/severity could be explained by serum cholesterol and age. A highly significant correlation between the various methods for quantitation of atherosclerosis extent and/or severity...... was demonstrated, suggesting that quantitative microscopy, macroscopic morphometry and determination of aortic cholesterol content may be equally valid as a measure of atherosclerosis in WHHL rabbits and are therefore interchangeable....

  3. Adsorption of ionic surfactants at microscopic air-water interfaces using the micropipette interfacial area-expansion method

    DEFF Research Database (Denmark)

    Kinoshita, Koji; Parra, Elisa; Needham, David

    2017-01-01

    The dynamic adsorption of ionic surfactants at air-water interfaces have been less-well studied than that of the simpler non-ionics since experimental limitations on dynamic surface tension (DST) measurements create inconsistencies in their kinetic analysis. Using our newly designed "Micropipette...... interfacial area-expansion method", we have measured and evaluated both equilibrium and dynamic adsorption of a well-known anionic surfactant, sodium dodecyl sulphate (SDS), in the absence or presence of 100mM NaCl. Our focus was to determine if and to what extent the inclusion of a new correction parameter...... for the "ideal ionic activity", A±i, can renormalize both equilibrium and dynamic surface tension measurements and provide better estimates of the diffusion coefficient of ionic surfactants in aqueous media obtained from electroneutral models, namely extended Frumkin isotherm and Ward-Tordai adsorption models...

  4. Microscopic unravelling of nano-carbon doping in MgB{sub 2} superconductors fabricated by diffusion method

    Energy Technology Data Exchange (ETDEWEB)

    Wong, D.C.K. [School of Physics, The University of Sydney, New South Wales 2006 (Australia); Yeoh, W.K. [School of Aerospace, Mechanical and Mechatronic Engineering, The University of Sydney, New South Wales 2006 (Australia); Australian Centre for Microscopy & Microanalysis, The University of Sydney, New South Wales 2006 (Australia); De Silva, K.S.B. [Institute for Superconducting & Electronic Materials, University of Wollongong, North Wollongong, New South Wales 2500 (Australia); Institute for Nanoscale Technology, Faculty of Science, University of Technology Sydney, Ultimo, New South Wales 2007 (Australia); Kondyurin, A.; Bao, P. [School of Physics, The University of Sydney, New South Wales 2006 (Australia); Li, W.X. [School of Materials Science and Engineering, Shanghai University, Shanghai 200072 (China); Xu, X.; Peleckis, G.; Dou, S.X. [Institute for Superconducting & Electronic Materials, University of Wollongong, North Wollongong, New South Wales 2500 (Australia); Ringer, S.P. [School of Aerospace, Mechanical and Mechatronic Engineering, The University of Sydney, New South Wales 2006 (Australia); Australian Centre for Microscopy & Microanalysis, The University of Sydney, New South Wales 2006 (Australia); Zheng, R.K., E-mail: rongkun.zheng@sydney.edu.au [School of Physics, The University of Sydney, New South Wales 2006 (Australia)

    2015-09-25

    Highlights: • First report on nano-carbon doped MgB{sub 2} superconductors synthesized by diffusion method. • Microstructure and superconducting properties of the superconductors are discussed. • B{sub 4}C region blocks the Mg from reacting with B in the 10% nano-carbon doped sample. • MgB{sub 2} with 2.5% nano-carbon doped showed the highest J{sub c}, ≈10{sup 4} A/cm{sup 2} for 20 K at 4 T. - Abstract: We investigated the effects of nano-carbon doping as the intrinsic (B-site nano-carbon substitution) and extrinsic (nano-carbon derivatives) pinning by diffusion method. The contraction of the in-plane lattice confirmed the presence of disorder in boron sublattice caused by carbon substitution. The increasing value in full width half maximum (FWHM) in the X-ray diffraction (XRD) patterns with each increment in the doping level reveal smaller grains and imperfect MgB{sub 2} crystalline. The strain increased across the doping level due to the carbon substitution in the MgB{sub 2} matrix. The broadening of the T{sub c} curves from low to high doping showed suppression of the connectivity of the bulk samples with progressive dirtying. At high doping, the presence of B{sub 4}C region blocked the Mg from reacting with crystalline B thus hampering the formation of MgB{sub 2}. Furthermore, the unreacted Mg acted as a current blocking phase in lowering down the grain connectivity hence depressing the J{sub c} of the 10% nano-carbon doped MgB{sub 2} bulk superconductor.

  5. Microscopic unravelling of nano-carbon doping in MgB2 superconductors fabricated by diffusion method

    International Nuclear Information System (INIS)

    Wong, D.C.K.; Yeoh, W.K.; De Silva, K.S.B.; Kondyurin, A.; Bao, P.; Li, W.X.; Xu, X.; Peleckis, G.; Dou, S.X.; Ringer, S.P.; Zheng, R.K.

    2015-01-01

    Highlights: • First report on nano-carbon doped MgB 2 superconductors synthesized by diffusion method. • Microstructure and superconducting properties of the superconductors are discussed. • B 4 C region blocks the Mg from reacting with B in the 10% nano-carbon doped sample. • MgB 2 with 2.5% nano-carbon doped showed the highest J c , ≈10 4 A/cm 2 for 20 K at 4 T. - Abstract: We investigated the effects of nano-carbon doping as the intrinsic (B-site nano-carbon substitution) and extrinsic (nano-carbon derivatives) pinning by diffusion method. The contraction of the in-plane lattice confirmed the presence of disorder in boron sublattice caused by carbon substitution. The increasing value in full width half maximum (FWHM) in the X-ray diffraction (XRD) patterns with each increment in the doping level reveal smaller grains and imperfect MgB 2 crystalline. The strain increased across the doping level due to the carbon substitution in the MgB 2 matrix. The broadening of the T c curves from low to high doping showed suppression of the connectivity of the bulk samples with progressive dirtying. At high doping, the presence of B 4 C region blocked the Mg from reacting with crystalline B thus hampering the formation of MgB 2 . Furthermore, the unreacted Mg acted as a current blocking phase in lowering down the grain connectivity hence depressing the J c of the 10% nano-carbon doped MgB 2 bulk superconductor

  6. Parsing the Dictionary of Modern Literary Russian Language with the Method of SCD Configurations. The Lexicographic Modeling

    Directory of Open Access Journals (Sweden)

    Neculai Curteanu

    2012-05-01

    Full Text Available This paper extends the experience of parsing other five, sensibly different, Romanian, French, and German largest dictionaries, to \\textbf{\\textit{DMLRL}} (Dictionary of Modern Literary Russian Language [18], using the optimal and portable parsing method of SCD (Segmentation-Cohesion-Dependency configurations [7], [11], [15]. The purpose of the present paper is to elaborate the lexicographic modeling of \\textbf{\\textit{DMLRL}}, which necessarily precedes the sense tree parsing dictionary entries. The following \\textbf{\\textit{three}} SCD configurations are described: the \\textbf{\\textit{first one}} has to separate the lexicographic segments in a \\textbf{\\textit{DMLRL}} entry, the \\textbf{\\textit{second}} SCD-configuration concentrates on the SCD marker classes and their hypergraph hierarchy for \\textbf{\\textit{DMLRL}} primary and secondary senses, while the \\textbf{\\textit{third}} SCD configuration hands down the same modeling process to the atomic sense definitions and their examples-to-definitions. The dependency hypergraph of the third SCD configuration, interconnected to the one of the second SCD configuration, is specified completely at the atomic sense level for the first time, exceeding the SCD configuration modeling for other five dictionaries [15], [14]. Numerous examples from \\textbf{\\textit{DMLRL}} and comparison to \\textbf{\\textit{DLR-DAR}} Romanian thesaurus-dictionary support the proposed \\textbf{\\textit{DMLRL}} lexicographic modeling.

  7. [Microscopic soil fungi - bioindicators organisms contaminated soil].

    Science.gov (United States)

    Donerian, L G; Vodianova, M A; Tarasova, Zh E

    In the paper there are considered methodological issues for the evaluation of soil biota in terms of oil pollution. Experimental studies have shown that under the exposure of a various levels of oil pollution meeting certain gradations of the state and optimal alteration in microbocenosis in sod-podzolic soils, there is occurred a transformation of structure of the complex of micromycetes and the accumulation of toxic species, hardly typical for podzolic soils - primarily represantatives of the genus Aspergillus (A.niger and A. versicolor), Paecilomyces (P.variotii Bainer), Trichoderma (T.hamatum), the genus of phytopathogens Fusarium (F.oxysporum), dermatophytes of genus Sporothrix (S. schenckii) and dark-colored melanin containing fungi of Dematiaceae family. Besides that there are presented data on the study of microbiocenosis of the urban soil, the urban soil differed from the zone soil, but shaped in similar landscape and climatic conditions, and therefore having a tendency to a similar response from the side of microorganisms inhabiting the soil. Isolated complex of soil microscopic fungi is described by many authors as a complex, characteristic for soils of megalopolises. This allowed authors of this work to suggest that in urban soils the gain in the occurrence of pathogenic species micromycetes also increases against a background of chronic, continuously renewed inflow of petroleum hydrocarbons from various sources of pollution. Because changes in the species composition of micromycetes occurred in accordance with the increasing load of oil, so far as microscopic soil fungi can be recommended as a bioindicator organisms for oil. In the article there is also provided information about the distinctive features of modern DNA identification method of soil microscopic fungi and accepted in our country methodology of isolation of micromycetes with the use of a nutrient Czapek medium.

  8. Method of mechanical holding of cantilever chip for tip-scan high-speed atomic force microscope

    Energy Technology Data Exchange (ETDEWEB)

    Fukuda, Shingo [Department of Physics, College of Science and Engineering, Kanazawa University, Kakuma-machi, Kanazawa 920-1192 (Japan); Uchihashi, Takayuki; Ando, Toshio [Department of Physics, College of Science and Engineering, Kanazawa University, Kakuma-machi, Kanazawa 920-1192 (Japan); Bio-AFM Frontier Research Center, College of Science and Engineering, Kanazawa University, Kakuma-machi, Kanazawa 920-1192 (Japan); Core Research for Evolutional Science and Technology of the Japan Science and Technology Agency, 7 Goban-cho, Chiyoda-ku, Tokyo 102-0076 (Japan)

    2015-06-15

    In tip-scan atomic force microscopy (AFM) that scans a cantilever chip in the three dimensions, the chip body is held on the Z-scanner with a holder. However, this holding is not easy for high-speed (HS) AFM because the holder that should have a small mass has to be able to clamp the cantilever chip firmly without deteriorating the Z-scanner’s fast performance, and because repeated exchange of cantilever chips should not damage the Z-scanner. This is one of the reasons that tip-scan HS-AFM has not been established, despite its advantages over sample stage-scan HS-AFM. Here, we present a novel method of cantilever chip holding which meets all conditions required for tip-scan HS-AFM. The superior performance of this novel chip holding mechanism is demonstrated by imaging of the α{sub 3}β{sub 3} subcomplex of F{sub 1}-ATPase in dynamic action at ∼7 frames/s.

  9. Modern optimization with R

    CERN Document Server

    Cortez, Paulo

    2014-01-01

    The goal of this book is to gather in a single document the most relevant concepts related to modern optimization methods, showing how such concepts and methods can be addressed using the open source, multi-platform R tool. Modern optimization methods, also known as metaheuristics, are particularly useful for solving complex problems for which no specialized optimization algorithm has been developed. These methods often yield high quality solutions with a more reasonable use of computational resources (e.g. memory and processing effort). Examples of popular modern methods discussed in this book are: simulated annealing; tabu search; genetic algorithms; differential evolution; and particle swarm optimization. This book is suitable for undergraduate and graduate students in Computer Science, Information Technology, and related areas, as well as data analysts interested in exploring modern optimization methods using R.

  10. Problems and prospects of modern methods of business analysis in the process of assessment of solvency of borrowers

    Directory of Open Access Journals (Sweden)

    Aptekar Saveliy S.

    2013-03-01

    Full Text Available The goal of the article is a comparative analysis of modern methods of business analysis in the process of assessment of solvency of borrowers of Ukrainian commercial banks, study of prospects and problems of the use of methods in the credit process. In the result of the study the article systemises and considers the conduct of the credit process of Ukrainian commercial banks. It becomes clear from result of the study that it is impossible to obtain a single assessment of solvency of a borrower with generalisation of numerical and non-numerical data. Assessment of qualified analysts is required for a justified assessment of solvency apart from information represented in numbers. Improvement of approaches to assessment of solvency of borrowers and adaptation of the existing foreign experience in this field to specific features of formation of solvency of Ukrainian borrowers are important tasks for the Ukrainian banking system. Prospects of further studies in this direction are establishment of importance of the conduct of business analysis and its key role in assessment of solvency of borrowers as a main instrument of minimisation of the credit risk. Improvement of this sphere of analytical work in Ukrainian banks should be carried out in the following main directions: study and analysis of qualitative indicators of business activity; analysis of main sections of the business plan; expansion of the composition of indicators of the financial analysis for obtaining information; conduct of analysis of possible sources of repayment of loan liabilities; and active use of analysis of cash flows of an enterprise.

  11. The Scanning Optical Microscope.

    Science.gov (United States)

    Sheppard, C. J. R.

    1978-01-01

    Describes the principle of the scanning optical microscope and explains its advantages over the conventional microscope in the improvement of resolution and contrast, as well as the possibility of producing a picture from optical harmonies generated within the specimen.

  12. Modernity: Are Modern Times Different?

    Directory of Open Access Journals (Sweden)

    Lynn Hunt

    2014-12-01

    Full Text Available “Modernity” has recently been the subject of considerable discussion among historians. This article reviews some of the debates and argues that modernity is a problematic concept because it implies a complete rupture with “traditional” ways of life. Studies of key terms are undertaken with the aid of Google Ngrams. These show that “modernity,” “modern times,” and “traditional” —in English and other languages— have a history of their own. A brief analysis of the shift from a self oriented toward equilibrium to a self oriented toward stimulation demonstrates that modernity is not necessary to historical analysis.

  13. STM-SQUID probe microscope

    International Nuclear Information System (INIS)

    Hayashi, Tadayuki; Tachiki, Minoru; Itozaki, Hideo

    2007-01-01

    We have developed a STM-SQUID probe microscope. A high T C SQUID probe microscope was combined with a scanning tunneling microscope for investigation of samples at room temperature in air. A high permeability probe needle was used as a magnetic flux guide to improve the spatial resolution. The probe with tip radius of less than 100 nm was prepared by microelectropolishing. The probe was also used as a scanning tunneling microscope tip. Topography of the sample surface could be measured by the scanning tunneling microscope with high spatial resolution prior to observation by SQUID microscopy. The SQUID probe microscope image could be observed while keeping the distance from the sample surface to the probe tip constant. We observed a topographic image and a magnetic image of Ni fine pattern and also a magnetically recorded hard disk. Furthermore we have investigated a sample vibration method of the static magnetic field emanating from a sample with the aim of achieving a higher signal-to-noise (S/N) ratio

  14. Differentials of modern contraceptive methods use by food security status among married women of reproductive age in Wolaita Zone, South Ethiopia.

    Science.gov (United States)

    Feyisso, Mohammed; Belachew, Tefera; Tesfay, Amanuel; Addisu, Yohannes

    2015-01-01

    In spite of the massive spending and extensive family-planning promotion, many poor people in the third world remain reluctant to use modern contraceptive method. Mostly when they use modern contraceptives, their continuation rates are often low. Reproductive health can improve women's nutrition; in return better nutrition can improve reproductive health. Thus addressing the connection between nutrition and reproductive health is critical to ensure population growth that does not overwhelm world resources. A community based cross-sectional study was conducted from March 15-30, 2014 in Soddo Zuria Woreda, Southern Ethiopia. A total of 651 currently married women of reproductive age group were selected using multistage sampling. Probability proportional to the size allocation method was employed to determine the number of households. Multivariable logistic regression was used to assess the association between family planning use and food security status after adjusting for other covariates. Use of modern contraceptive method was significantly low among food insecure women (29.7 %) compared to those who were food secure (52.0 %), (P insecurity is negatively associated with modern contraceptive method use. Thus food insecurity should be considered as one of the barriers in designing family planning services and needs special arrangement.

  15. How Do Zoos "Talk" to Their General Visitors? Do Visitors "Listen"? A Mixed Method Investigation of the Communication between Modern Zoos and Their General Visitors

    Science.gov (United States)

    Roe, Katie; McConney, Andrew; Mansfield, Caroline F.

    2014-01-01

    Modern zoos utilise a variety of education tools for communicating with visitors. Previous research has discussed the benefits of providing multiple education communications, yet little research provides an indication of what communications are being employed within zoos today. This research is a two-phased, mixed-methods investigation into the…

  16. An ImageJ-based algorithm for a semi-automated method for microscopic image enhancement and DNA repair foci counting

    International Nuclear Information System (INIS)

    Klokov, D.; Suppiah, R.

    2015-01-01

    Proper evaluation of the health risks of low-dose ionizing radiation exposure heavily relies on the ability to accurately measure very low levels of DNA damage in cells. One of the most sensitive methods for measuring DNA damage levels is the quantification of DNA repair foci that consist of macromolecular aggregates of DNA repair proteins, such as γH2AX and 53BP1, forming around individual DNA double-strand breaks. They can be quantified using immunofluorescence microscopy and are widely used as markers of DNA double-strand breaks. However this quantification, if performed manually, may be very tedious and prone to inter-individual bias. Low-dose radiation studies are especially sensitive to this potential bias due to a very low magnitude of the effects anticipated. Therefore, we designed and validated an algorithm for the semi-automated processing of microscopic images and quantification of DNA repair foci. The algorithm uses ImageJ, a freely available image analysis software that is customizable to individual cellular properties or experimental conditions. We validated the algorithm using immunolabeled 53BP1 and γH2AX in normal human fibroblast AG01522 cells under both normal and irradiated conditions. This method is easy to learn, can be used by nontrained personnel, and can help avoiding discrepancies in inter-laboratory comparison studies examining the effects of low-dose radiation. (author)

  17. An ImageJ-based algorithm for a semi-automated method for microscopic image enhancement and DNA repair foci counting

    Energy Technology Data Exchange (ETDEWEB)

    Klokov, D., E-mail: dmitry.klokov@cnl.ca [Canadian Nuclear Laboratories, Chalk River, Ontario (Canada); Suppiah, R. [Queen' s Univ., Dept. of Biomedical and Molecular Sciences, Kingston, Ontario (Canada)

    2015-06-15

    Proper evaluation of the health risks of low-dose ionizing radiation exposure heavily relies on the ability to accurately measure very low levels of DNA damage in cells. One of the most sensitive methods for measuring DNA damage levels is the quantification of DNA repair foci that consist of macromolecular aggregates of DNA repair proteins, such as γH2AX and 53BP1, forming around individual DNA double-strand breaks. They can be quantified using immunofluorescence microscopy and are widely used as markers of DNA double-strand breaks. However this quantification, if performed manually, may be very tedious and prone to inter-individual bias. Low-dose radiation studies are especially sensitive to this potential bias due to a very low magnitude of the effects anticipated. Therefore, we designed and validated an algorithm for the semi-automated processing of microscopic images and quantification of DNA repair foci. The algorithm uses ImageJ, a freely available image analysis software that is customizable to individual cellular properties or experimental conditions. We validated the algorithm using immunolabeled 53BP1 and γH2AX in normal human fibroblast AG01522 cells under both normal and irradiated conditions. This method is easy to learn, can be used by nontrained personnel, and can help avoiding discrepancies in inter-laboratory comparison studies examining the effects of low-dose radiation. (author)

  18. A Contribution To The Development And Analysis Of A Combined Current-Voltage Instrument Transformer By Using Modern CAD Methods

    International Nuclear Information System (INIS)

    Chundeva-Blajer, Marija M.

    2004-01-01

    The principle aim and task of the thesis is the analysis and development of 20 kV combined current-voltage instrument transformer (CCVIT) by using modern CAD techniques. CCVIT is a complex electromagnetic system comprising of four windings and two magnetic cores in one insulation housing for simultaneous transformation of high voltages and currents to measurable signal values by standard instruments. The analytical design methods can be applied on simple electromagnetic configurations, which is not the case with the CCVIT. There is mutual electromagnetic influence between the voltage measurement core (VMC) and the current measurement core (CMC). After the analytical CCVIT design had been done, exact determination of its metrological characteristics has been accomplished by using the numerical finite element method implemented in the FEM-3D program package. The FEM-3D calculation is made in 19 cross-sectional layers of the z-axis of the CCVIT three-dimensional domain. By FEM-3D application the three-dimensional CCVIT magnetic field distribution is derived. This is the basis for calculation of the initial metrological characteristics of the CCVIT (VMC is accuracy class 3 and CMC is accuracy class 1). By using the stochastic optimization technique based on genetic algorithm the CCVIT optimal design is achieved. The objective function is the minimum of the metrological parameters (VIM voltage error and CMC current error). There are I I independent input variables during the optimization process by which the optimal project is derived. The optimal project is adapted for realization of a prototype and the optimized project is derived. Full comparative analysis of the metrological and the electromagnetic characteristics of the three projects is accomplished. By application of the program package MATLAB/SIMULINK the CCVIT transient phenomena is analyzed for different regimes in the three design projects. In the Instrument Transformer Factory of EMO A. D.-Ohrid a CCVIT

  19. Modern cosmology

    International Nuclear Information System (INIS)

    Zeldovich, Y.B.

    1983-01-01

    This paper fives a general review of modern cosmology. The following subjects are discussed: hot big bang and periodization of the evolution; Hubble expansion; the structure of the universe (pancake theory); baryon asymmetry; inflatory universe. (Auth.)

  20. Autoradiographic detection of [125I]-secondary antiserum: a sensitive light and electron microscopic labeling method compatible with peroxidase immunocytochemistry for dual localization of neuronal antigens

    International Nuclear Information System (INIS)

    Pickel, V.M.; Chan, J.; Milner, T.A.

    1986-01-01

    We examined whether autoradiographic localization of [ 125 I]-antirabbit immunoglobulin (IgG) was suitable for light and electron microscopic detection of a rabbit antiserum to the catecholamine-synthesizing enzyme, tyrosine hydroxylase (TH), and whether autoradiographic and peroxidase labeling could be combined for simultaneous immunocytochemical identification of TH and neuropeptides in brain. Adult rat brains were fixed by aortic arch perfusion with acrolein and paraformaldehyde. Vibratome sections of the fixed tissues were incubated with various dilutions of TH antiserum followed by [ 125 I]-secondary IgG. These sections were then directly processed for autoradiography or were incubated with rabbit antiserum to substance P (SP) or methionine [Met5]-enkephalin (ME). These latter sections were then processed by the peroxidase-antiperoxidase (PAP) or conjugated peroxidase methods followed by autoradiography. Exposure periods of 12-20 days for light microscopy or 90 days for electron microscopy yielded substantial accumulations of silver grains even at the highest (1:30,000) dilution of TH antiserum. At this dilution, immunoreactivity for TH was virtually nondetectable by PAP and conjugated peroxidase methods. The differential sensitivities of the autoradiographic versus peroxidase methods provided a means for separable identification of rabbit antiserum to TH and to SP or ME. Ultrastructural analysis of the catecholaminergic neurons in the medial nuclei of the solitary tract (NTS) showed selective cytoplasmic localization of silver grains for [ 125 I]-labeling of TH in perikarya, dendrites, and terminals. Within single thin sections prepared for dual labeling, the peroxidase marker for SP and for ME was differentially localized with respect to autoradiographic labeling of TH

  1. Chemical and Physical Methods to Analyze a Multicomponent Traditional Chinese Herbal Prescription Using LC-MS/MS, Electron Microscope, and Congo Red Staining

    Directory of Open Access Journals (Sweden)

    Chia-Ming Lu

    2013-01-01

    Full Text Available This study develops several chemical and physical methods to evaluate the quality of a traditional Chinese formulation, Jia-Wei-Xiao-Yao-San. Liquid chromatography-tandem mass spectrometry (LC-MS/MS coupled with electrospray ionization was used to measure the herbal biomarkers of saikosaponin A, saikosaponin D, ferulic acid, and paeoniflorin from this herbal formula. A scanning electron microscope (SEM and light microscopy photographs with Congo red staining were used to identify the cellulose fibers if raw herbal powder had been added to the herbal pharmaceutical product. Moreover, water solubility and crude fiber content examination were used to inspect for potential herbal additives to the herbal pharmaceutical products. The results demonstrate that the contents of the herbal ingredients of saikosaponin A, saikosaponin D, ferulic acid, and paeoniflorin were around 0.351 ± 0.017, 0.136 ± 0.010, 0.140 ± 0.005, and 2.281 ± 0.406 mg/g, respectively, for this herbal pharmaceutical product. The physical examination data demonstrate that the raw herbal powder had rough, irregular, lumpy, filamentous, and elongated shapes, as well as strong Congo red staining. In addition, water solubility and crude fiber content were not consistent in the herbal pharmaceutical products.

  2. Anisotropic contrast optical microscope.

    Science.gov (United States)

    Peev, D; Hofmann, T; Kananizadeh, N; Beeram, S; Rodriguez, E; Wimer, S; Rodenhausen, K B; Herzinger, C M; Kasputis, T; Pfaunmiller, E; Nguyen, A; Korlacki, R; Pannier, A; Li, Y; Schubert, E; Hage, D; Schubert, M

    2016-11-01

    An optical microscope is described that reveals contrast in the Mueller matrix images of a thin, transparent, or semi-transparent specimen located within an anisotropic object plane (anisotropic filter). The specimen changes the anisotropy of the filter and thereby produces contrast within the Mueller matrix images. Here we use an anisotropic filter composed of a semi-transparent, nanostructured thin film with sub-wavelength thickness placed within the object plane. The sample is illuminated as in common optical microscopy but the light is modulated in its polarization using combinations of linear polarizers and phase plate (compensator) to control and analyze the state of polarization. Direct generalized ellipsometry data analysis approaches permit extraction of fundamental Mueller matrix object plane images dispensing with the need of Fourier expansion methods. Generalized ellipsometry model approaches are used for quantitative image analyses. These images are obtained from sets of multiple images obtained under various polarizer, analyzer, and compensator settings. Up to 16 independent Mueller matrix images can be obtained, while our current setup is limited to 11 images normalized by the unpolarized intensity. We demonstrate the anisotropic contrast optical microscope by measuring lithographically defined micro-patterned anisotropic filters, and we quantify the adsorption of an organic self-assembled monolayer film onto the anisotropic filter. Comparison with an isotropic glass slide demonstrates the image enhancement obtained by our method over microscopy without the use of an anisotropic filter. In our current instrument, we estimate the limit of detection for organic volumetric mass within the object plane of ≈49 fg within ≈7 × 7 μm 2 object surface area. Compared to a quartz crystal microbalance with dissipation instrumentation, where contemporary limits require a total load of ≈500 pg for detection, the instrumentation demonstrated here improves

  3. Microscopic Theory of Transconductivity

    Directory of Open Access Journals (Sweden)

    A. P. Jauho

    1998-01-01

    Full Text Available Measurements of momentum transfer between two closely spaced mesoscopic electronic systems, which couple via Coulomb interaction but where tunneling is inhibited, have proven to be a fruitful method of extracting information about interactions in mesoscopic systems. We report a fully microscopic theory for transconductivity σ12, or, equivalently, momentum transfer rate between the system constituents. Our main formal result expresses the transconductivity in terms of two fluctuation diagrams, which are topologically related, but not equivalent to, the Azlamazov-Larkin and Maki-Thompson diagrams known for superconductivity. In the present paper the magnetic field dependence of σ12 is discussed, and we find that σ12(B is strongly enhanced over its zero field value, and it displays strong features, which can be understood in terms of a competition between density-of-states and screening effects.

  4. Modern Methods of Reconstruction of the Sacral Objects - Example of the Jasna Gora Monastery in Czestochowa, Poland

    Science.gov (United States)

    Kazhar, Nina

    2017-10-01

    This publication is devoted to the problem of preservation and restoration of the architectural monument as an element of the historical environment. The notion of “immovable monument of history and culture” is specified. Modern methods of restoration and repair-conservatory works are analyzed. The main principles of complex studies of monument buildings are considered taking into account their interactions with the environment. The necessity of assessing the physical state of structures and materials of the architectural monument for selecting the optimal technology for repair work, preserving the historical and cultural landscape is shown. A brief history of the construction and repair of the monastery at Jasna Gora in Czestochowa (Poland) is presented. The restoration of the Jasna Gora ensemble was a complex kind of construction work: repair, conservation, consolidation and renovation of architectural monuments. The ground and underground structures of the main buildings and structures have been restored and strengthened. The program of restoration work on the task “Complex restoration of the building of the monastery of the Paulin Fathers on Jasna Gora” (2004-2013) included three stages: 1. “Reconstruction and restoration of the buildings of the monastery of the Paulin Fathers on Jasna Gora” (2007-2010), 2. “Conservation and renovation of the building of the Basilica of the Holy Cross and the Nativity of the Virgin” (2007-2012), 3. “Renovation of the North curtain - the entrance to the territory of the monastery of the Paulin Fathers on Jasna Gora” (2013). Restoration was based on a thorough examination of the monument and aimed to maximally preserve the historical, constructive and artistic features of the monastery complex, ensure its long existence. In addition to preserving the historical, technical and artistic qualities of the ensemble of the monastery, the tasks of organizing the environmental monument were resolved. Completed

  5. Microscopic description of nuclear reactions

    International Nuclear Information System (INIS)

    Gorbatov, A.M.

    1992-01-01

    The genealogical series method has been extended to the continuous spectrum of the many-body systems. New nonlinear integral equations have been formulated to perform the microscopical description of the nuclear reactions with arbitrary number of particles. The way to solve them numerically is demonstrated

  6. Cryogenic immersion microscope

    Science.gov (United States)

    Le Gros, Mark; Larabell, Carolyn A.

    2010-12-14

    A cryogenic immersion microscope whose objective lens is at least partially in contact with a liquid reservoir of a cryogenic liquid, in which reservoir a sample of interest is immersed is disclosed. When the cryogenic liquid has an index of refraction that reduces refraction at interfaces between the lens and the sample, overall resolution and image quality are improved. A combination of an immersion microscope and x-ray microscope, suitable for imaging at cryogenic temperatures is also disclosed.

  7. Microscopic collective models of nuclei

    International Nuclear Information System (INIS)

    Lovas, Rezsoe

    1985-01-01

    Microscopic Rosensteel-Rowe theory of the nuclear collective motion is described. The theoretical insufficiency of the usual microscopic establishment of the collective model is pointed. The new model treating exactly the degrees of freedom separates the coordinates describing the collective motion and the internal coordinates by a consistent way. Group theoretical methods analyzing the symmetry properties of the total Hamiltonian are used defining the collective subspaces transforming as irreducible representations of the group formed by the collective operators. Recent calculations show that although the results of the usual collective model are approximately correct and similar to those of the new microscopic collective model, the underlying philosophy of the old model is essentially erroneous. (D.Gy.)

  8. Analytical Electron Microscope

    Data.gov (United States)

    Federal Laboratory Consortium — The Titan 80-300 is a transmission electron microscope (TEM) equipped with spectroscopic detectors to allow chemical, elemental, and other analytical measurements to...

  9. Scanning Color Laser Microscope

    Science.gov (United States)

    Awamura, D.; Ode, T.; Yonezawa, M.

    1988-01-01

    A confocal color laser microscope which utilizes a three color laser light source (Red: He-Ne, Green: Ar, Blue: Ar) has been developed and is finding useful applications in the semiconductor field. The color laser microscope, when compared to a conventional microscope, offers superior color separation, higher resolution, and sharper contrast. Recently some new functions including a Focus Scan Memory, a Surface Profile Measurement System, a Critical Dimension Measurement system (CD) and an Optical Beam Induced Current Function (OBIC) have been developed for the color laser microscope. This paper will discuss these new features.

  10. FEVER AS KEY SYMPTOM OF ACUTE RESPIRATORY INFECTIONS AND MODERN METHODS OF THERAPY FOR HIGH TEMPERATURE IN CHILDREN

    Directory of Open Access Journals (Sweden)

    O.A. Solntseva

    2010-01-01

    Full Text Available Hyperthermia is the key symptom of acute respiratory infections (ARI. An increase in the body temperature is accompanied with phagocytosis activation, increased interferon synthesis, antibody genesis stimulation, lymphocytes activation and differentiation. Nevertheless, significant hyperthermia may result in my unfavourable consequences. It may particularly cause an exacerbation of chronic diseases. Modern therapy for hyperthermia is, therefore, an important aspect of treating children with ARI. The article outlines the modern approach to treating fever in children, identifies key criteria for selecting a medication. It also contains a case study of applying ibuprofen and data from various trials which verify the rationale for applying ibuprofen in children with hyperthermia that developed in conjunction with ARI.Key words: children, acute respiratory infections, hyperthermia, ibuprofen.(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5:80-84

  11. The Homemade Microscope.

    Science.gov (United States)

    Baker, Roger C., Jr.

    1991-01-01

    Directions for the building of a pocket microscope that will make visible the details of insect structure and living bacteria are described. Background information on the history of microscopes and lenses is provided. The procedures for producing various types of lenses are included. (KR)

  12. Mailing microscope slides

    Science.gov (United States)

    Many insects feed agriculturally important crops, trees, and ornamental plants and cause millions of dollars of damage annually. Identification for some of these require the preparation of a microscope slide for examination. There are times when a microscope slide may need to be sent away to a speci...

  13. Biogeosystem technique as a method to overcome the Biological and Environmental Hazards of modern Agricultural, Irrigational and Technological Activities

    Science.gov (United States)

    Kalinitchenko, Valery; Batukaev, Abdulmalik; Zinchenko, Vladimir; Zarmaev, Ali; Magomadov, Ali; Chernenko, Vladimir; Startsev, Viktor; Bakoev, Serojdin; Dikaev, Zaurbek

    2014-05-01

    Modern challenge for humanity is to replace the paradigm of nature use and overcome environmental hazards of agronomy, irrigation, industry, and other human activities in biosphere. It is utterly reasonable to stop dividing biosphere on shares - the human habitat and the environment. In the 21st century it is an outdated anthropocentrism. Contradicting himself to biosphere Humankind has the problems. The new paradigm of biosphere control by methods of Biogeosystem technique is on agenda of Humankind. Key directions of Biogeosystem technique. Tillage. Single rotary milling 20…30-50…60 sm soil layer optimizes the evolution and environment of soil, creates a favorable conditions for the rhizosphere, increases the biological productivity of biosphere by 30-50% compared to the standard agricultural practices for the period up to 40 years. Recycle material. Recycling of mineral and organic substances in soil layer of 20…30-50…60 sm in rotary milling soil processing provides wastes clean return to biosphere. Direct intrasoil substances synthesis. Environmentally friendly robot wasteless nanotechnology provides direct substances synthesis, including fertilizers, inside the soil. It eliminates the prerequisites of the wastes formation under standard industrial technologies. Selective substance's extraction from soil. Electrochemical robotic nanotechnology provides selective substances extraction from soil. The technology provides recovery, collection and subsequent safe industrial use of extracted substances out of landscape. Saving fresh water. An important task is to save fresh water in biosphere. Irrigation spends water 4-5 times more of biological requirements of plants, leads to degradation of soil and landscape. The intrasoil pulse continuous-discrete paradigm of irrigation is proposed. It provides the soil and landscape conservation, increases the biological productivity, save the fresh water up to 10-20 times. The subsurface soil rotary processing and

  14. Special issue introduction: Ecological modernization

    DEFF Research Database (Denmark)

    Massa, Ilmo; Andersen, Mikael Skou

    2000-01-01

    The contributions to this special issue of the Journal of Environmental Policy and Planning stem from an international conference on ecological modernization that took place at the Department of Social Policy of the University of Helsinki, Finland, in late 1998. They have been selected, among other...... reasons, for their possible contribution to conceptual understanding and clarification. While recent publications have explored the implications of ecological modernization in different settings (Mol & Sonnenfeld, 2000), here we try to put the concept under the microscope again, in the hope of clarifying...

  15. Development on analytical method of computational dynamic property and optimum design method of texture construction considering microscopic texture of the materials for nuclear powers

    International Nuclear Information System (INIS)

    Shiraishi, Haruki

    1997-01-01

    In structural design of the nuclear reactor core, He void boundary embrittlement used for a factor of determining using temperature limit of the structural materials is said to be formed by He void present at the crystal particles boundary. However, it has been not succeeded in quantitative estimation on ductility of the materials containing He voids formed on neutron radiation. In this paper, the results of qualitative analysis on effect of voids shapes (size and density) on the boundary He embrittlement were reported. Using two-dimensional elastoplastic finite element method, stress-strain curve of the materials containing voids at crystal boundary was analyzed. At that time, suppositions such as continuous body dynamics, Von Mises yield condition, n-power hardening rule, repeating boundary condition and so on were adopted. As a result, it was found that deformation type was divided to inter-particle deformation and boundary deformation types, and that so-called boundary He embrittlement was belonged to the latter. (G.K.)

  16. Italian Modernities

    DEFF Research Database (Denmark)

    Thomassen, Bjørn; Forlenza, Rosario

    assumptions that have substituted for thought and that have perpetuated prejudices both within and outside Italy’s borders. Grounded in meticulous historical and ethnological research, Italian Modernities deserves as wide an audience as its scholarship is deep.” (Michael Herzfeld, Ernest E. Monrad Professor...

  17. Montreal Modern

    DEFF Research Database (Denmark)

    Handberg, Kristian

    2015-01-01

    , and the space age modernism of the 1960s following the Expo 67 and Quebec’s Quiet Revolution. This is reflected in the city’s thriving retro culture through the study of two groups of retro shops. In circulating specific memories and objects in a specific context, retro is an important negotiation of the past...

  18. Modern Supersymmetry

    International Nuclear Information System (INIS)

    Kulish, Petr P

    2006-01-01

    We have spent more than twenty years applying supersymmetry (SUSY) to elementary particle physics and attempting to find an experimental manifestation of this symmetry. Terning's monograph demonstrates the strong influence of SUSY on theoretical elaborations in the field of elementary particles. It gives both an overview of modern supersymmetry in elementary particle physics and calculation techniques. The author, trying to be closer to applications of SUSY in the real world of elementary particles, is also anticipating the importance of supersymmetry for rigorous study of nonperturbative phenomena in quantum field theory. In particular, he presents the 'exact' SUSY β function using instanton methods, phenomena of anomalies and dualities. Supersymmetry algebra is introduced by adding two anticommuting spinor generators to Poincare algebra and by presenting massive and massless supermultiplets of its representations. The author prefers to use mostly the component description of field contents of the theories in question rather than the superfield formalism. Such a style makes the account closer to physical characteristics. Relations required by SUSY among β functions of the gauge, Yukawa and quartic interactions are checked by direct calculations as well as to all orders in perturbation theory, thus demonstrating that SUSY survives quantization. A discussion is included of the hierarchy problem of different scales of weak and strong interactions and its possible solution by the minimal supersymmetric standard model. Different SUSY breaking mechanisms are presented corresponding to a realistic phenomenology. The monograph can also be considered as a guide to 'duality' relations connecting different SUSY gauge theories, supergravities and superstrings. This is demonstrated referring to the particular properties and characteristics of these theories (field contents, scaling dimensions of appropriate operators etc). In particular, the last chapter deals with the Ad

  19. The efficiency of conventional microscopic selection is comparable to the hyaluronic acid binding method in selecting spermatozoa for male infertility patients

    Directory of Open Access Journals (Sweden)

    Meng-Ting Huang

    2015-02-01

    Conclusion: The percentages of DNA intact spermatozoa between the PVP-sperm and HA-sperm groups were not significantly different. In an ICSI procedure, a well-trained embryologist will have the same ability to choose sperm with intact DNA by conventional microscopic selection as with HA-bound spermatozoa selection.

  20. Microscopic morphology and apoptosis of ovarian tissue after cryopreservation using a vitrification method in post-hatching turkey poults, Meleagris gallopavo

    Science.gov (United States)

    1. Microscopic morphology of ovarian tissue in post-hatching turkey poults at various ages was investigated. 2. Hematoxylin and eosin staining were used and the diameter of the oocytes and follicles were measured using microphotography. 3. Immediately after hatching, oocytes in one-day turkey pou...

  1. Transients of modern power electronics

    CERN Document Server

    Bai, Hua

    2011-01-01

    In high power, high voltage electronics systems, a strategy to manage short timescale energy imbalances is fundamental to the system reliability. Without a theoretical framework, harmful local convergence of energy can affect the dynamic process of transformation, transmission, and storage which create an unreliable system. With an original approach that encourages understanding of both macroscopic and microscopic factors, the authors offer a solution. They demonstrate the essential theory and methodology for the design, modeling and prototyping of modern power electronics converters to crea

  2. Modern vs. Traditional.

    Science.gov (United States)

    Zhenhui, Rao

    1999-01-01

    This article discusses traditional methods, such as the grammar-translation, and modern methods, the communicative approach, for teaching English-as-a-foreign-language in China. The relationship between linguistic accuracy and communicative competence, student-centered orientation, and the role of the teacher are highlighted. (Author/VWL)

  3. Modern Cosmology

    CERN Document Server

    Zhang Yuan Zhong

    2002-01-01

    This book is one of a series in the areas of high-energy physics, cosmology and gravitation published by the Institute of Physics. It includes courses given at a doctoral school on 'Relativistic Cosmology: Theory and Observation' held in Spring 2000 at the Centre for Scientific Culture 'Alessandro Volta', Italy, sponsored by SIGRAV-Societa Italiana di Relativita e Gravitazione (Italian Society of Relativity and Gravitation) and the University of Insubria. This book collects 15 review reports given by a number of outstanding scientists. They touch upon the main aspects of modern cosmology from observational matters to theoretical models, such as cosmological models, the early universe, dark matter and dark energy, modern observational cosmology, cosmic microwave background, gravitational lensing, and numerical simulations in cosmology. In particular, the introduction to the basics of cosmology includes the basic equations, covariant and tetrad descriptions, Friedmann models, observation and horizons, etc. The ...

  4. Modern bureaucracy

    OpenAIRE

    Toye, John

    2006-01-01

    Max Weber believed that bureaucracy could be understood by analysing its ideal-typical characteristics, and that these characteristics would become more pervasive as the modern age advanced. Weber’s horizontal account of bureaucracy can be criticised on various grounds, including its unrealistic notion of bureaucratic rationality. An alternative view is proposed, namely, that the development of state bureaucracies is driven by the trajectory of the highpower politics in which they are nested....

  5. Modern Biology

    OpenAIRE

    ALEKSIC, Branko

    2014-01-01

    The purpose of this course is to learn the philosophy, principles, and techniques of modern biology. The course is particularly designed for those who have not learned biology previously or whose major is other than biology, and who may think that they do not need to know any biology at all. The topics are covered in a rather general, overview manner, but certain level of diligence in grasping concepts and memorizing the terminology is expected.

  6. Modern maths

    CERN Multimedia

    Thom,R

    1974-01-01

    Le Prof. R. Thom expose ses vues sur l'enseignement des mathématiques modernes et des mathémathiques de toujours. Il est un grand mathématicien et était professeur à Strasbourg; maintenant il est professeur de hautes études scientifiques et était invité par le Prof. Piaget à Genève

  7. New insights into urban planning of Caričin Grad: The application of modern sensing and detection methods

    Directory of Open Access Journals (Sweden)

    Ivanišević Vujadin

    2016-01-01

    Full Text Available Caričin Grad, Justiniana Prima, urban planning, fortification, settlement, aerial photography, geophysical surveys, LiDAR, photogrammetry, excavations, GIS. Thanks to the application of modern non-destructive sensing and detection methods, in recent years a series of new data on urban planning in Caričin Grad was obtained. For the most part, the current research programme studies the Upper Town’s northern plateau, wooded until recently and hence the only previously unexplored unit of the city. In the course of this programme, the classical research method - the excavations started in 2009 - is for the first time combined with the systematic application of airborne and terrestrial sensing and detection techniques. The analysis of historic aerial photographs and topographic plans proved to be very useful as well. Along with them, LiDAR-derived DTMs, photogrammetric DEMs, different geophysical and orthophotographic plans are stored in the GIS database for Caričin Grad and the Leskovac Basin. In this way almost 80 percent of the plateau area was defined, and the obtained plan is hypothetical only to a small extent, which particularly refers to the unexcavated northern rampart of the Upper Town. Each source provided relevant information for the reconstruction of both the rampart and the settlement, which points to the value of a holistic approach to documentation from various dates. The first source to be studied were archival aerial photographs of Caričin Grad from 1938 and 1947 (Figs. 1, 2.1. The latter one was originally processed by Aleksandar Deroko and Svetozar Radojči}, who drew the plan of the town after it, labelling the unexplored Upper Town’s northern plateau as “a probable habitation area”. The route of the northern rampart was aslo rather precisely determined by the authors (Fig. 2.2. Recently, these photographs were rectified and georeferenced in the GIS. The 1938 shot reveals the position of some towers as well, and it is

  8. A comparative study of modern and fossil cone scales and seeds of conifers: A geochemical approach

    Science.gov (United States)

    Artur, Stankiewicz B.; Mastalerz, Maria; Kruge, M.A.; Van Bergen, P. F.; Sadowska, A.

    1997-01-01

    Modern cone scales and seeds of Pinus strobus and Sequoia sempervirens, and their fossil (Upper Miocene, c. 6 Mar) counterparts Pinus leitzii and Sequoia langsdorfi have been studied using pyrolysis-gas chromatography/mass spectrometry (Py-GC/MS), electron-microprobe and scanning electron microscopy. Microscopic observations revealed only minor microbial activity and high-quality structural preservation of the fossil material. The pyrolysates of both modern genera showed the presence of ligno-cellulose characteristic of conifers. However, the abundance of (alkylated)phenols and 1,2-benzenediols in modern S. sempervirens suggests the presence of non-hydrolysable tannins or abundant polyphenolic moieties not previously reported in modern conifers. The marked differences between the pyrolysis products of both modern genera are suggested to be of chemosystematic significance. The fossil samples also contained ligno-cellulose which exhibited only partial degradation, primarily of the carbohydrate constituents. Comparison between the fossil cone scale and seed pyrolysates indicated that the ligno-cellulose complex present in the seeds is chemically more resistant than that in the cone scales. Principal component analysis (PCA) of the pyrolysis data allowed for the determination of the discriminant functions used to assess the extent of degradation and the chemosystematic differences between both genera and between cone scales and seeds. Elemental composition (C, O, S), obtained using electron-microprobe, corroborated the pyrolysis results. Overall, the combination of chemical, microscopic and statistical methods allowed for a detailed characterization and chemosystematic interpretations of modern and fossil conifer cone scales and seeds.

  9. Green Building between Tradition and Modernity Study Comparative Analysis between Conventional Methods and Updated Styles of Design and Architecture Processors

    Directory of Open Access Journals (Sweden)

    H Elshimy

    2017-03-01

    Full Text Available Green house   concept appeared from the ancient to the modern age ages and there is a tendency to use a traditional architecture with a pristine ecological environment areas and through sophisticated systems arrived to modern systems of the upgraded systems by Treatment architectural achieve environmental   sustainability   in   recent   years,   sustainability concept has become the common interest of numerous disciplines. The reason for this popularity is to perform the sustainable development. The Concept of Green Architecture, also known as "sustainable architecture” or “green house,” is the theory, science and style of buildings designed and constructed in accordance   with environmentally   friendly   principles.   Green house strives to minimize the number of resources consumed in the   building's  construction,   use   and   operation,   as  well  as curtailing  the  harm  done  to  the  environment  through  the emission, pollution and waste of its components.To design, construct, operate and maintain buildings energy, water and new materials are utilized as well as amounts of waste causing negative effects to health and environment is generated. In order to limit these effects and design environmentally sound and resource efficient buildings; "green building systems" must be introduced, clarified, understood and practiced.This paper aims at highlighting these difficult and complex issues of sustainability which encompass the scope of almost every aspect of human life.

  10. Scanning Auger Electron Microscope

    Data.gov (United States)

    Federal Laboratory Consortium — A JEOL model 7830F field emission source, scanning Auger microscope.Specifications / Capabilities:Ultra-high vacuum (UHV), electron gun range from 0.1 kV to 25 kV,...

  11. Microscopic approach to polaritons

    DEFF Research Database (Denmark)

    Skettrup, Torben

    1981-01-01

    contrary to experimental experience. In order to remove this absurdity the semiclassical approach must be abandoned and the electromagnetic field quantized. A simple microscopic polariton model is then derived. From this the wave function for the interacting exciton-photon complex is obtained...... of light of the crystal. The introduction of damping smears out the excitonic spectra. The wave function of the polariton, however, turns out to be very independent of damping up to large damping values. Finally, this simplified microscopic polariton model is compared with the exact solutions obtained...... for the macroscopic polariton model by Hopfield. It is seen that standing photon and exciton waves must be included in an exact microscopic polariton model. However, it is concluded that for practical purposes, only the propagating waves are of importance and the simple microscopic polariton wave function derived...

  12. Differential magnetic force microscope imaging.

    Science.gov (United States)

    Wang, Ying; Wang, Zuobin; Liu, Jinyun; Hou, Liwei

    2015-01-01

    This paper presents a method for differential magnetic force microscope imaging based on a two-pass scanning procedure to extract differential magnetic forces and eliminate or significantly reduce background forces with reversed tip magnetization. In the work, the difference of two scanned images with reversed tip magnetization was used to express the local magnetic forces. The magnetic sample was first scanned with a low lift distance between the MFM tip and the sample surface, and the magnetization direction of the probe was then changed after the first scan to perform the second scan. The differential magnetic force image was obtained through the subtraction of the two images from the two scans. The theoretical and experimental results have shown that the proposed method for differential magnetic force microscope imaging is able to reduce the effect of background or environment interference forces, and offers an improved image contrast and signal to noise ratio (SNR). © Wiley Periodicals, Inc.

  13. Infrared microscope inspection apparatus

    Science.gov (United States)

    Forman, Steven E.; Caunt, James W.

    1985-02-26

    Apparatus and system for inspecting infrared transparents, such as an array of photovoltaic modules containing silicon solar cells, includes an infrared microscope, at least three sources of infrared light placed around and having their axes intersect the center of the object field and means for sending the reflected light through the microscope. The apparatus is adapted to be mounted on an X-Y translator positioned adjacent the object surface.

  14. The efficiency of conventional microscopic selection is comparable to the hyaluronic acid binding method in selecting spermatozoa for male infertility patients.

    Science.gov (United States)

    Huang, Meng-Ting; Kuo-Kuang Lee, Robert; Lu, Chung-Hao; Chen, Ying-Jie; Li, Sheng-Hsiang; Hwu, Yuh-Ming

    2015-02-01

    To evaluate if hyaluronic acid (HA)-bound spermatozoa surpassed conventional microscopy-selected spermatozoa in the status of sperm DNA integrity by acridine orange (AO) fluorescence staining. Spermatozoa obtained from couples with indication for the intracytoplasmic sperm injection (ICSI) procedure due to male infertility (n = 34) and control males with normal sperm parameters (n = 12) were analyzed using AO fluorescence staining after density-gradient centrifugation (DGC), polyvinylpyrrolidone (PVP)-microscopic selection, and HA-binding selection to determine sperm DNA integrity. Percentages of DNA intact spermatozoa with green fluorescence were significantly higher in both PVP-microscopic selected spermatozoa (82.1 ± 24.0%) and HA-bound spermatozoa (83.9 ± 21.1%) than in spermatozoa prepared by DGC (66.8 ± 24.0%). However, there was no significant difference between the PVP-sperm and HA-sperm groups. When the percentage of green fluorescent spermatozoa prepared by DGC fell initially below 68%, both PVP-microscopic and HA-binding selection failed to select over 90% spermatozoa with intact DNA for ICSI in the male infertility group. Compared to control males with normal sperm parameters (99.3 ± 1.8%), the proportion of green fluorescence sperm after HA-binding selection from couples with male infertility (83.9 ± 21.1%) did not reach the range of > 99% reported by Yagci et al. The percentages of DNA intact spermatozoa between the PVP-sperm and HA-sperm groups were not significantly different. In an ICSI procedure, a well-trained embryologist will have the same ability to choose sperm with intact DNA by conventional microscopic selection as with HA-bound spermatozoa selection. Copyright © 2014. Published by Elsevier B.V.

  15. Modern Cosmology

    Energy Technology Data Exchange (ETDEWEB)

    Zhang Yuanzhong

    2002-06-21

    This book is one of a series in the areas of high-energy physics, cosmology and gravitation published by the Institute of Physics. It includes courses given at a doctoral school on 'Relativistic Cosmology: Theory and Observation' held in Spring 2000 at the Centre for Scientific Culture 'Alessandro Volta', Italy, sponsored by SIGRAV-Societa Italiana di Relativita e Gravitazione (Italian Society of Relativity and Gravitation) and the University of Insubria. This book collects 15 review reports given by a number of outstanding scientists. They touch upon the main aspects of modern cosmology from observational matters to theoretical models, such as cosmological models, the early universe, dark matter and dark energy, modern observational cosmology, cosmic microwave background, gravitational lensing, and numerical simulations in cosmology. In particular, the introduction to the basics of cosmology includes the basic equations, covariant and tetrad descriptions, Friedmann models, observation and horizons, etc. The chapters on the early universe involve inflationary theories, particle physics in the early universe, and the creation of matter in the universe. The chapters on dark matter (DM) deal with experimental evidence of DM, neutrino oscillations, DM candidates in supersymmetry models and supergravity, structure formation in the universe, dark-matter search with innovative techniques, and dark energy (cosmological constant), etc. The chapters about structure in the universe consist of the basis for structure formation, quantifying large-scale structure, cosmic background fluctuation, galaxy space distribution, and the clustering of galaxies. In the field of modern observational cosmology, galaxy surveys and cluster surveys are given. The chapter on gravitational lensing describes the lens basics and models, galactic microlensing and galaxy clusters as lenses. The last chapter, 'Numerical simulations in cosmology', deals with spatial and

  16. Modern plasmonics

    CERN Document Server

    Maradudin, Alexei A; Barnes, William L

    2014-01-01

    Plasmonics is entering the curriculum of many universities, either as a stand alone subject, or as part of some course or courses. Nanotechnology institutes have been, and are being, established in universities, in which plasmonics is a significant topic of research. Modern Plasmonics book offers a comprehensive presentation of the properties of surface plasmon polaritons, in systems of different structures and various natures, e.g. active, nonlinear, graded, theoretical/computational and experimental techniques for studying them, and their use in a variety of applications. Contains materia

  17. Modern spectroscopy

    CERN Document Server

    Hollas, J Michael

    2013-01-01

    The latest edition of this highly acclaimed title introduces the reader to a wide range of spectroscopies, and includes both the background theory and applications to structure determination and chemical analysis.  It covers rotational, vibrational, electronic, photoelectron and Auger spectroscopy, as well as EXAFs and the theory of lasers and laser spectroscopy. A  revised and updated edition of a successful, clearly written book Includes the latest developments in modern laser techniques, such as cavity ring-down spectroscopy and femtosecond lasers Provides numerous worked examples, calculations and questions at the end of chapters.

  18. Design Method for Contra-Rotating Propellers for High-Speed Crafts: Revising the Original Lerbs Theory in a Modern Perspective

    Directory of Open Access Journals (Sweden)

    Stefano Brizzolara

    2012-01-01

    Full Text Available The main theoretical and numerical aspects of a design method for optimum contrar-rotating (CR propellers for fast marine crafts are presented. We propose a reformulated version of a well-known design theory for contra-rotating propellers, by taking advantage of a new fully numerical algorithm for the calculation of the mutually induced velocities and introducing new features such as numerical lifting surface corrections, use of an integrated modern cavitation/strength criteria, a modified method to consider different numbers of blades among the two propellers, and to allow for an unloading function in the search for the optimal circulation distribution. The paper first introduces the main theoretical principles of the new methods and then discusses the influence of the main design parameters on an emblematic example of application in the case of counter rotating propellers for a pod propulsor designed for fast planing crafts (35 knots and above.

  19. eSIP: A Novel Solution-Based Sectioned Image Property Approach for Microscope Calibration.

    Directory of Open Access Journals (Sweden)

    Malte Butzlaff

    Full Text Available Fluorescence confocal microscopy represents one of the central tools in modern sciences. Correspondingly, a growing amount of research relies on the development of novel microscopic methods. During the last decade numerous microscopic approaches were developed for the investigation of various scientific questions. Thereby, the former qualitative imaging methods became replaced by advanced quantitative methods to gain more and more information from a given sample. However, modern microscope systems being as complex as they are, require very precise and appropriate calibration routines, in particular when quantitative measurements should be compared over longer time scales or between different setups. Multispectral beads with sub-resolution size are often used to describe the point spread function and thus the optical properties of the microscope. More recently, a fluorescent layer was utilized to describe the axial profile for each pixel, which allows a spatially resolved characterization. However, fabrication of a thin fluorescent layer with matching refractive index is technically not solved yet. Therefore, we propose a novel type of calibration concept for sectioned image property (SIP measurements which is based on fluorescent solution and makes the calibration concept available for a broader number of users. Compared to the previous approach, additional information can be obtained by application of this extended SIP chart approach, including penetration depth, detected number of photons, and illumination profile shape. Furthermore, due to the fit of the complete profile, our method is less susceptible to noise. Generally, the extended SIP approach represents a simple and highly reproducible method, allowing setup independent calibration and alignment procedures, which is mandatory for advanced quantitative microscopy.

  20. Self-directed learning can outperform direct instruction in the course of a modern German medical curriculum - results of a mixed methods trial.

    Science.gov (United States)

    Peine, Arne; Kabino, Klaus; Spreckelsen, Cord

    2016-06-03

    Modernised medical curricula in Germany (so called "reformed study programs") rely increasingly on alternative self-instructed learning forms such as e-learning and curriculum-guided self-study. However, there is a lack of evidence that these methods can outperform conventional teaching methods such as lectures and seminars. This study was conducted in order to compare extant traditional teaching methods with new instruction forms in terms of learning effect and student satisfaction. In a randomised trial, 244 students of medicine in their third academic year were assigned to one of four study branches representing self-instructed learning forms (e-learning and curriculum-based self-study) and instructed learning forms (lectures and seminars). All groups participated in their respective learning module with standardised materials and instructions. Learning effect was measured with pre-test and post-test multiple-choice questionnaires. Student satisfaction and learning style were examined via self-assessment. Of 244 initial participants, 223 completed the respective module and were included in the study. In the pre-test, the groups showed relatively homogenous scores. All students showed notable improvements compared with the pre-test results. Participants in the non-self-instructed learning groups reached scores of 14.71 (seminar) and 14.37 (lecture), while the groups of self-instructed learners reached higher scores with 17.23 (e-learning) and 15.81 (self-study). All groups improved significantly (p learning group, whose self-assessment improved by 2.36. The study shows that students in modern study curricula learn better through modern self-instructed methods than through conventional methods. These methods should be used more, as they also show good levels of student acceptance and higher scores in personal self-assessment of knowledge.

  1. Modern electronic maintenance principles

    CERN Document Server

    Garland, DJ

    2013-01-01

    Modern Electronic Maintenance Principles reviews the principles of maintaining modern, complex electronic equipment, with emphasis on preventive and corrective maintenance. Unfamiliar subjects such as the half-split method of fault location, functional diagrams, and fault finding guides are explained. This book consists of 12 chapters and begins by stressing the need for maintenance principles and discussing the problem of complexity as well as the requirements for a maintenance technician. The next chapter deals with the connection between reliability and maintenance and defines the terms fai

  2. Modern thermodynamics

    CERN Document Server

    Ben-Naim, Arieh

    2017-01-01

    This textbook introduces thermodynamics with a modern approach, starting from four fundamental physical facts (the atomic nature of matter, the indistinguishability of atoms and molecules of the same species, the uncertainty principle, and the existence of equilibrium states) and analyzing the behavior of complex systems with the tools of information theory, in particular with Shannon's measure of information (or SMI), which can be defined on any probability distribution. SMI is defined and its properties and time evolution are illustrated, and it is shown that the entropy is a particular type of SMI, i.e. the SMI related to the phase-space distribution for a macroscopic system at equilibrium. The connection to SMI allows the reader to understand what entropy is and why isolated systems follow the Second Law of Thermodynamics. The Second Llaw is also formulated for other systems, not thermally isolated and even open with respect to the transfer of particles. All the fundamental aspects of thermodynamics are d...

  3. Modern electrodynamics

    CERN Document Server

    Zangwill, Andrew

    2013-01-01

    An engaging writing style and a strong focus on the physics make this comprehensive, graduate-level textbook unique among existing classical electromagnetism textbooks. Charged particles in vacuum and the electrodynamics of continuous media are given equal attention in discussions of electrostatics, magnetostatics, quasistatics, conservation laws, wave propagation, radiation, scattering, special relativity and field theory. Extensive use of qualitative arguments similar to those used by working physicists makes Modern Electrodynamics a must-have for every student of this subject. In 24 chapters, the textbook covers many more topics than can be presented in a typical two-semester course, making it easy for instructors to tailor courses to their specific needs. Close to 120 worked examples and 80 applications boxes help the reader build physical intuition and develop technical skill. Nearly 600 end-of-chapter homework problems encourage students to engage actively with the material. A solutions manual is availa...

  4. Occupational concerns associated with regular use of microscope

    OpenAIRE

    Garima Jain; Pushparaja Shetty

    2014-01-01

    Objectives: Microscope work can be strenuous both to the visual system and the musculoskeletal system. Lack of awareness or indifference towards health issues may result in microscope users becoming victim to many occupational hazards. Our objective was to understand the occupational problems associated with regular use of microscope, awareness regarding the hazards, attitude and practice of microscope users towards the problems and preventive strategies. Material and Methods: A questionnaire...

  5. Electron microscope studies

    International Nuclear Information System (INIS)

    Crewe, A.V.; Kapp, O.H.

    1992-01-01

    This is a report covering the research performed in the Crewe laboratory between 1964 and 1992. Because of limitations of space we have provided relatively brief summaries of the major research directions of the facility during these years. A complete bibliography has been included and we have referenced groups of pertinent publications at the beginning of each section. This report summarizes our efforts to develop better electron microscopes and chronicles many of the experimental programs, in materials science and biology, that acted both as a stimulus to better microscope design and also as a testing ground for many instrumental innovations

  6. Electron microscope studies

    Energy Technology Data Exchange (ETDEWEB)

    Crewe, A.V.; Kapp, O.H.

    1992-07-01

    This is a report covering the research performed in the Crewe laboratory between 1964 and 1992. Because of limitations of space we have provided relatively brief summaries of the major research directions of the facility during these years. A complete bibliography has been included and we have referenced groups of pertinent publications at the beginning of each section. This report summarizes our efforts to develop better electron microscopes and chronicles many of the experimental programs, in materials science and biology, that acted both as a stimulus to better microscope design and also as a testing ground for many instrumental innovations.

  7. The microscopic (optical and SEM) examination of dental calculus deposits (DCD). Potential interest in forensic anthropology of a bio-archaeological method.

    Science.gov (United States)

    Charlier, Philippe; Huynh-Charlier, Isabelle; Munoz, Olivia; Billard, Michel; Brun, Luc; de la Grandmaison, Geoffroy Lorin

    2010-07-01

    This article describes the potential interest in forensic anthropology of the microscopic analysis of dental calculus deposits (DCD), a calcified residue frequently found on the surface of teeth. Its sampling and analysis seem straightforward and relatively reproducible. Samples came from archaeological material (KHB-1 Ra's al-Khabbah and RH-5 Ra's al-Hamra, two Prehistoric graveyards located in the Sultanate of Oman, dated between the 5th and 4th millennium B.C.; Montenzio Vecchia, an Etruscan-Celtic necropolis from the north of Italy, dated between the 5th and 3rd century B.C.; body rests of Agnès Sorel, French royal mistress died in 1450 A.D.; skeleton of Pierre Hazard, French royal notary from the 15th century A.D.). Samples were studies by direct optical microscope (OM) or scanning electron microscopy (SEM). Many cytological, histological and elemental analyses were possible, producing precious data for the identification of these remains, the reconstitution of their alimentation and occupational habits, and propositions for manner of death. Copyright 2010 Elsevier Ireland Ltd. All rights reserved.

  8. MODERN METHODS OF COMPETENCE BUILDING APPROACH IMPLEMENTATION IN THE SYSTEM OF TRAINING SPECIALISTS IN HIGHER EDUCATIONAL ESTABLISHMENTS

    Directory of Open Access Journals (Sweden)

    E. G. Gutsu

    2014-01-01

    Full Text Available The article discusses a problem of the changing of requirements of professional competence of teacher of university connected with transition to a competence model of professional education. The article tackles upon the problem of using the portfolio method in the process of the article introduces the short review of such notions as: forms and different variants of using methods. Besides, the author of the article points out the use of the portfolio method in the training of the specialists (social teachers, teachers of primary school during the whole process of studying at the Pedagogical Institute.

  9. Statistical Methods for Population Genetic Inference Based on Low-Depth Sequencing Data from Modern and Ancient DNA

    DEFF Research Database (Denmark)

    Korneliussen, Thorfinn Sand

    Due to the recent advances in DNA sequencing technology genomic data are being generated at an unprecedented rate and we are gaining access to entire genomes at population level. The technology does, however, not give direct access to the genetic variation and the many levels of preprocessing...... that is required before being able to make inferences from the data introduces multiple levels of uncertainty, especially for low-depth data. Therefore methods that take into account the inherent uncertainty are needed for being able to make robust inferences in the downstream analysis of such data. This poses...... a problem for a range of key summary statistics within populations genetics where existing methods are based on the assumption that the true genotypes are known. Motivated by this I present: 1) a new method for the estimation of relatedness between pairs of individuals, 2) a new method for estimating...

  10. Demand for family planning satisfied with modern methods among sexually active women in low- and middle-income countries: who is lagging behind?

    Science.gov (United States)

    Ewerling, Fernanda; Victora, Cesar G; Raj, Anita; Coll, Carolina V N; Hellwig, Franciele; Barros, Aluisio J D

    2018-03-06

    Family planning is key for reducing unintended pregnancies and their health consequences and is also associated with improvements in economic outcomes. Our objective was to identify groups of sexually active women with extremely low demand for family planning satisfied with modern methods (mDFPS) in low- and middle-income countries, at national and subnational levels to inform the improvement and expansion of programmatic efforts to narrow the gaps in mDFPS coverage. Analyses were based on Demographic and Health Survey and Multiple Indicator Cluster Survey data. The most recent surveys carried out since 2000 in 77 countries were included in the analysis. We estimated mDFPS among women aged 15-49 years. Subgroups with low coverage (mDFPS below 20%) were identified according to marital status, wealth, age, education, literacy, area of residence (urban or rural), geographic region and religion. Overall, only 52.9% of the women with a demand for family planning were using a modern contraceptive method, but coverage varied greatly. West & Central Africa showed the lowest coverage (32.9% mean mDFPS), whereas South Asia and Latin America & the Caribbean had the highest coverage (approximately 70% mean mDFPS). Some countries showed high reliance on traditional contraceptive methods, markedly those from Central and Eastern Europe, and the Commonwealth of Independent States (CEE & CIS). Albania, Azerbaijan, Benin, Chad and Congo Democratic Republic presented low mDFPS coverage (planning method. Subgroups requiring special attention include women who are poor, uneducated/illiterate, young, and living in rural areas. Efforts to increase mDFPS must address not only the supply side but also tackle the need to change social norms that might inhibit uptake of contraception.

  11. Microscope on Mars

    Science.gov (United States)

    2004-01-01

    This image taken at Meridiani Planum, Mars by the panoramic camera on the Mars Exploration Rover Opportunity shows the rover's microscopic imager (circular device in center), located on its instrument deployment device, or 'arm.' The image was acquired on the ninth martian day or sol of the rover's mission.

  12. The scanning tunneling microscope

    International Nuclear Information System (INIS)

    Salvan, F.

    1986-01-01

    A newly conceived microscope, based on a pure quantum phenomenon, is an ideal tool to study atom by atom the topography and properties of surfaces. Applications are presented: surface ''reconstruction'' of silicon, lamellar compound study, etc... Spectroscopy by tunnel effect will bring important information on electronic properties; it is presented with an application on silicon [fr

  13. Scanning electron microscope

    International Nuclear Information System (INIS)

    Anon.

    1980-01-01

    The principle underlying the design of the scanning electron microscope (SEM), the design and functioning of SEM are described. Its applications in the areas of microcircuitry and materials science are outlined. The development of SEM in India is reviewed. (M.G.B.)

  14. Modern logic and quantum mechanics

    International Nuclear Information System (INIS)

    Garden, R.W.

    1984-01-01

    The book applies the methods of modern logic and probabilities to ''interpreting'' quantum mechanics. The subject is described and discussed under the chapter headings: classical and quantum mechanics, modern logic, the propositional logic of mechanics, states and measurement in mechanics, the traditional analysis of probabilities, the probabilities of mechanics and the model logic of predictions. (U.K.)

  15. Modern methods of experimental construction of texture complete direct pole figures by using X-ray data

    Science.gov (United States)

    Isaenkova, M.; Perlovich, Yu; Fesenko, V.

    2016-04-01

    Currently used methods for constructing texture complete direct pole figure (CDPF) based on the results of X-ray diffractometric measurements were considered with respect to the products of Zr-based alloys and, in particular, used in a nuclear reactor cladding tubes, for which the accuracy of determination of integral texture parameters is of the especial importance. The main attention was devoted to technical issues which are solved by means of computer processing of large arrays of obtained experimental data. Among considered questions there are amendments of the defocusing, techniques for constructing of complete direct pole figures and determination of integral textural parameters. The methods of reconstruction of complete direct pole figures by partial direct pole figures recorded up to tilt angles of sample ψ=70-80°: the method of extrapolation of data to an uninvestigated region of the stereographic projection, and the method of "sewing" of partial pole figures measured for three mutually perpendicular plane sections of the product. The limits of applicability of these methods, depending on the shape of the test product and the degree of inhomogeneity of the layer-by-layer texture, were revealed. On the basis of a large number of experimental data, the accuracy of the integral parameters used for calculation of the physical and mechanical properties of metals with a hexagonal crystal structure was found to be equal to 0.02, when taking into account the texture heterogeneity of regular products from Zr-based alloys.

  16. Modern methods of evaluation existing suppliers and suppliers selected by customer for small and medium-sized companies

    Directory of Open Access Journals (Sweden)

    Marie Jurová

    2010-01-01

    Full Text Available On existing conditions on global market (almost identical quality, almost identical purchasing values companies have to definite the total rating of importance of evaluative criteria. In post-crisis period the problem of suppliers’ evaluation is one of the biggest, because companies had to use all resources and all possibilities to develop their own business. Many authors wrote about collaborative planning and warehousing as one of possibilities to optimization work inside supply chain. For this paper define small and medium-sized enterprises (SME as enterprises with the size of maximum 250 em­ployers. In literature was read we couldn’t find information about own system of suppliers evaluation for small and medium-sized enterprises. SME can have some different types of business and in this case need the universal system of eva­lua­tion. The research of this paper is oriented on small and medium-sized enterprises with different types of business. The new theoretical universal method of calculation for evaluation existing suppliers for small and medium-sized enterprises will present in this paper. This theoretical method is based on average values. This method includes traditional evaluative criteria (quality, delivery time and other (mobility of supplier, possibilities of new level of partnership. This method of evaluation can not be used for continual manufacture. New method can improve the total evaluation of supplier in small and medium-sized enterprises.

  17. Multi-compartment microscopic diffusion imaging

    OpenAIRE

    Kaden, Enrico; Kelm, Nathaniel D.; Carson, Robert P.; Does, Mark D.; Alexander, Daniel C.

    2016-01-01

    This paper introduces a multi-compartment model for microscopic diffusion anisotropy imaging. The aim is to estimate microscopic features specific to the intra- and extra-neurite compartments in nervous tissue unconfounded by the effects of fibre crossings and orientation dispersion, which are ubiquitous in the brain. The proposed MRI method is based on the Spherical Mean Technique (SMT), which factors out the neurite orientation distribution and thus provides direct estimates of the microsco...

  18. A community-based, mixed-methods study of the attitudes and behaviors of men regarding modern family planning in Nigeria.

    Science.gov (United States)

    Akaba, Godwin; Ketare, Nathaniel; Tile, Wilfred

    2016-10-01

    To investigate the knowledge, attitudes, and extent of involvement of men in family planning in Nigeria, and to evaluate spousal communication regarding family planning. A community-based, mixed-methods study enrolled participants in Gwagwalada, Abuja, Nigeria between January 11 and June 30, 2012. Quantitative surveys including semi-structured interviews were used to collect information from married men regarding their knowledge and attitudes to modern family planning. The qualitative components constituted focus group discussion sessions and in-depth interviews that included married men, married women, religious leaders, community leaders, and family-planning providers. Quantitative surveys were completed by 152 men; 99 (65.1%) reported that they would accompany their wives to family-planning clinics in the future, 116 (76.3%) reported approving of the use of modern contraception by their wives, and 132 (86.8%) reported wanting to know more about family planning. Both quantitative and qualitative aspects of the study indicated that husbands were the major decision makers regarding family size, choice of contraceptive, and pregnancy timing. In terms of fertility goals and family planning, men were the primary decision makers; consequently, obtaining their support and commitment to family planning is of crucial importance in Nigeria. Copyright © 2016 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.

  19. Transition metal-catalyzed couplings of alkynes to 1,3-enynes: modern methods and synthetic applications.

    Science.gov (United States)

    Trost, Barry M; Masters, James T

    2016-04-21

    The metal-catalyzed coupling of alkynes is a powerful method for the preparation of 1,3-enynes, compounds that are of broad interest in organic synthesis. Numerous strategies have been developed for the homo- and cross coupling of alkynes to enynes via transition metal catalysis. In such reactions, a major issue is the control of regio-, stereo-, and, where applicable, chemoselectivity. Herein, we highlight prominent methods for the selective synthesis of these valuable compounds. Further, we illustrate the utility of these processes through specific examples of their application in carbocycle, heterocycle, and natural product syntheses.

  20. Self-consistent method for quantifying indium content from X-ray spectra of thick compound semiconductor specimens in a transmission electron microscope.

    Science.gov (United States)

    Walther, T; Wang, X

    2016-05-01

    Based on Monte Carlo simulations of X-ray generation by fast electrons we calculate curves of effective sensitivity factors for analytical transmission electron microscopy based energy-dispersive X-ray spectroscopy including absorption and fluorescence effects, as a function of Ga K/L ratio for different indium and gallium containing compound semiconductors. For the case of InGaN alloy thin films we show that experimental spectra can thus be quantified without the need to measure specimen thickness or density, yielding self-consistent values for quantification with Ga K and Ga L lines. The effect of uncertainties in the detector efficiency are also shown to be reduced. © 2015 The Authors Journal of Microscopy © 2015 Royal Microscopical Society.

  1. Computer simulation for precipitation process of θ (Ni3V) and γ' (Ni3Al) with microscopic phase-field method

    Institute of Scientific and Technical Information of China (English)

    HOU Hua; XU Hong; ZHAO Yu-hong

    2006-01-01

    With the microscopic phase-field model, the precipitation process of aged alloys was explored by computer simulation, which could clarify some discussional views on the precipitation mechanisms of alloys. The precipitation process of Ni75Al2.5V22.5 alloy was studied. From the simulated atomic pictures, calculated order parameters and volume fraction of different precipitates, it's found that the θ ordered phase precipitates earlier than γ' ordered phase by congruent ordering+spinodal decomposition mechanism and thus produces a nonstoicheometric θ single ordered phase. Then, the nonstoicheometric γ' phase is precipitated by a non-classical nucleation and growth mechanism at the APBS of θ phases. Meanwhile, both of them transform to stoicheometric ordered phases.

  2. METHODS OF PSYCHOSOCIAL REHABILITATION IN PSYCHIATRIC INSTITUTIONS OF THE ORYOL REGION AT THE MODERN STAGE OF ORGANIZATION OF PSYCHIATRIC CARE

    Directory of Open Access Journals (Sweden)

    G. R. Gardanova

    2015-01-01

    Full Text Available The article considers actual issues of psychosocial rehabilitation at the present stage of psychiatric care to the population of the Oryol region.The purpose. Study and generalize the experience of the use of methods of psychosocial rehabilitation in several psychiatric institutions of the Oryol region.Materials and methods. 1. The analysis of activity of out-patient departments, where we developed a new "development Program of sociorehabilitation service in regional psychoneurologic dispensary". 2. Analysis of the activity of hospital services, where the main role is played by psycho-social rehabilitation. 3. The analysis of new forms of psychosocial rehabilitation: in terms of the specifics of Oryol oblast psychiatric hospital of specialized type with intensive supervision (OPHSTIO.Results. As a result of the analysis we identified the most effective methods of sociorehabilitation: outpatient: "Social card of the outpatient" is intended for persons in need of social, psychological, legal and other professional assistance, that allows to plan and control the types of assistance provided. The organization of a hostel for patients at the outpatient stage, which allowed to introduce a "full" recovery cycle. In OPHSTIO — implementation of multiprofessional teams and "sick tips" and the opening of an Orthodox chapel of the Mother of God icon "All grieving pleasures".Conclusions. Methods of psychosocial rehabilitation allowed to optimize the work of the main stages of treatment and rehabilitation processes, to provide in a timely manner the necessary comprehensive care to patients based on individual needs of the mentally ill in the outpatient and inpatient therapy in the Oryol region.

  3. Retention of sulfur and nitrogen oxides from the exhaust gases by radiolysis, a modern method of environmental protection

    International Nuclear Information System (INIS)

    Macarie, Rodica; Zissulescu, Ecaterina; Martin, Diana; Radoiu, Marilena

    2000-01-01

    Industry, especially the power industry, is a great generator of gaseous pollutants (SO x , NO x , CO 2 , CO). The oxides are responsible for the 'acid rains' which have a great negative impact on the environment, human beings and animals, while CO 2 emissions contribute to the increase of the greenhouse effect. Retention of the sulfur and nitrogen oxides from the exhaust gases can be carried out either by conventional methods (using chemical adsorbents) or by non-conventional ones (radiolysis). Recently, non-conventional methods have bee given priority, including exhaust gas irradiation with an accelerated electron beam as a more efficient alternative to the gas desulfurization. In order to increase the efficiency of the accelerated electron beam injected into the exhaust gas, the effect of microwave utilization has been investigated. The company S.C. ICPET S.A.-Bucuresti, in cooperation with INFLPR-Bucuresti, investigated the retention by radiolysis of the sulfur and nitrogen oxides from a synthetic mixture of exhaust gases in an installation developed in the laboratory by means of accelerated electron beams, microwaves and by the accelerated electron beams and microwave combined. The paper presents the results obtained in the laboratory experiments and the advantages of radiolysis in comparison with the chemical conventional methods, namely: simultaneous removal of SO 2 and NO x , solid by-products that can be used as fertilizers in agriculture, simple technologies that do not imply catalysts or adsorbents, no waste waters. (authors)

  4. Evaluation of a completely robotized neurosurgical operating microscope.

    Science.gov (United States)

    Kantelhardt, Sven R; Finke, Markus; Schweikard, Achim; Giese, Alf

    2013-01-01

    Operating microscopes are essential for most neurosurgical procedures. Modern robot-assisted controls offer new possibilities, combining the advantages of conventional and automated systems. We evaluated the prototype of a completely robotized operating microscope with an integrated optical coherence tomography module. A standard operating microscope was fitted with motors and control instruments, with the manual control mode and balance preserved. In the robot mode, the microscope was steered by a remote control that could be fixed to a surgical instrument. External encoders and accelerometers tracked microscope movements. The microscope was additionally fitted with an optical coherence tomography-scanning module. The robotized microscope was tested on model systems. It could be freely positioned, without forcing the surgeon to take the hands from the instruments or avert the eyes from the oculars. Positioning error was about 1 mm, and vibration faded in 1 second. Tracking of microscope movements, combined with an autofocus function, allowed determination of the focus position within the 3-dimensional space. This constituted a second loop of navigation independent from conventional infrared reflector-based techniques. In the robot mode, automated optical coherence tomography scanning of large surface areas was feasible. The prototype of a robotized optical coherence tomography-integrated operating microscope combines the advantages of a conventional manually controlled operating microscope with a remote-controlled positioning aid and a self-navigating microscope system that performs automated positioning tasks such as surface scans. This demonstrates that, in the future, operating microscopes may be used to acquire intraoperative spatial data, volume changes, and structural data of brain or brain tumor tissue.

  5. Microscopic structure for light nuclei

    International Nuclear Information System (INIS)

    Sharma, V.K.

    1995-01-01

    The microscopic structure for light nuclei e.g. 4 He, 7 Li and 8 Be is considered in the frame work of the generator coordinate method (GCM). The physical interpretation of our GCM is also discussed. The GC amplitudes are used to calculate the various properties like charge and magnetic RMS radii, form factors, electromagnetic moments, astrophysical S-factor, Bremsstrahlung weighted cross sections, relative wavefunctions and vertex functions etc. All the calculated quantities agree well with the values determined experimentally. (author). 30 refs., 10 figs., 2 tabs

  6. Science Academies' Refresher Course on Modern Biotechnology ...

    Indian Academy of Sciences (India)

    IAS Admin

    , PCR and RT-PCR. A variety of teaching methods like lectures by eminent ... knowledge to boost their confidence in handling modern instruments used in the discipline of life sciences and modern biotechnology. Skills gained during this ...

  7. Modern methods for evaluating the workability of cement used as a binder for the stabilization and solidification of toxic wastes

    Energy Technology Data Exchange (ETDEWEB)

    De Angelis, Giorgio [ENEA, Centro Ricerche Casaccia, Rome (Italy). Dipt. Ambiente

    1997-10-01

    The workability of cement pastes has a great influence on the final properties of the solidified products, like mechanical strength, stability density and durability. This is quite relevant in the field of stabilization / solidification of toxic and hazardous wastes. Hence considerable importance attaches to having reliable control over the fresh concrete properties, especially its early stiffening behaviour. This paper discussers measuring methods of the stiffening of two different types of cement pastes, prepared with different water / cement ratios, and examines the possible consequences of the early stiffening of cement pastes on their set times and bleeding.

  8. Stress and displacement analysis of a modern design lathe body by the fi nite element method (FEM

    Directory of Open Access Journals (Sweden)

    R. Staniek

    2012-01-01

    Full Text Available The Finite element method (FEM was used in this study for the analysis of the strain and stress of a turning machine body. The fi nal design decisions were made on the basis of stress and displacement fi eld analysis of various design versions related to the structure of the considered machine tool. The results presented in this paper will be helpful for practical static and dynamic strength evaluation as well as for the appropriate design of machine tools using the FEM.

  9. Modern analytic methods applied to the art and archaeology; Metodos analiticos modernos aplicados al arte y la arqueologia

    Energy Technology Data Exchange (ETDEWEB)

    Tenorio C, M. D.; Longoria G, L. C., E-mail: dolores.tenorio@inin.gob.m [ININ, Departamento de Quimica, Carretera Mexico-Toluca s/n, 52750 Ocoyoacac, Estado de Mexico (Mexico)

    2010-07-01

    The interaction of diverse areas as the analytic chemistry, the history of the art and the archaeology has allowed the development of a variety of techniques used in archaeology, in conservation and restoration. These methods have been used to date objects, to determine the origin of the old materials and to reconstruct their use and to identify the degradation processes that affect the integrity of the art works. The objective of this chapter is to offer a general vision on the researches that have been realized in the Instituto Nacional de Investigaciones Nucleares (ININ) in the field of cultural goods. A series of researches carried out in collaboration with national investigators and of the foreigner is described shortly, as well as with the great support of degree students and master in archaeology of the National School of Anthropology and History, since one of the goals that have is to diffuse the knowledge of the existence of these techniques among the young archaeologists, so that they have a wider vision of what they could use in an in mediate future and they can check hypothesis with scientific methods. (Author)

  10. Investigation of the Utilization of Modern Industrial Methods, Processes, Ergonomics, and the Internet in the Scientific Environment

    Science.gov (United States)

    Myer, Spencer S., Jr.

    2005-01-01

    On Oct. 1, 2001 Cleveland State University and NASA Glenn Research Center embarked on the above named cooperative agreement. Because NASA's research facilities often exhibit instances where the failure to use state-of-the-art technologies and methods to improve on outmoded systems of interface and control, and this runs contrary to the NASA philosophy of "faster, better, and cheaper", it was deemed an ideal opportunity for this collaboration. The main objectives of the proposed effort were to research and investigate the use of the latest technologies, methods, techniques, etc. which pertain to control and interface with industrial and research systems and facilities. The work was done in large part at NASA Glenn Research Center, using selected research facilities as real-world laboratories; such as certain Microgravity Science Division and Space Station projects. Microgravity Science Division at Glenn Research Center designs and builds experiments to be flown on the Space Shuttle and eventually on the International Space Station. Economy of space, weight, complexity, data storage, ergonomics, and many other factors present problems that also exist in industry. Many of the solutions can come from the same areas of study mentioned above.

  11. Variable temperature superconducting microscope

    Science.gov (United States)

    Cheng, Bo; Yeh, W. J.

    2000-03-01

    We have developed and tested a promising type of superconducting quantum interference device (SQUID) microscope, which can be used to detect vortex motion and can operate in magnetic fields over a large temperature range. The system utilizes a single-loop coupling transformer, consisting of a patterned high Tc superconducting thin film. At one end of the transformer, a 20 μm diam detecting loop is placed close to the sample. At the other end, a large loop is coupled to a NbTi coil, which is connected to a low Tc SQUID sensor. Transformers in a variety of sizes have been tested and calibrated. The results show that the system is capable of detecting the motion of a single vortex. We have used the microscope to study the behavior of moving vortices at various positions in a YBa2Cu3O7 thin film bridge.

  12. Neuromorphic Data Microscope

    Energy Technology Data Exchange (ETDEWEB)

    Naegle, John H.; Suppona, Roger A.; Aimone, James Bradley; James, Conrad D.; Follett, David R.; Townsend, Duncan C.M.; Follett, Pamela L.; Karpman, Gabe D.

    2017-08-01

    In 2016, Lewis Rhodes Labs, (LRL), shipped the first commercially viable Neuromorphic Processing Unit, (NPU), branded as a Neuromorphic Data Microscope (NDM). This product leverages architectural mechanisms derived from the sensory cortex of the human brain to efficiently implement pattern matching. LRL and Sandia National Labs have optimized this product for streaming analytics, and demonstrated a 1,000x power per operation reduction in an FPGA format. When reduced to an ASIC, the efficiency will improve to 1,000,000x. Additionally, the neuromorphic nature of the device gives it powerful computational attributes that are counterintuitive to those schooled in traditional von Neumann architectures. The Neuromorphic Data Microscope is the first of a broad class of brain-inspired, time domain processors that will profoundly alter the functionality and economics of data processing.

  13. Microscopic dynamical Casimir effect

    Science.gov (United States)

    Souza, Reinaldo de Melo e.; Impens, François; Neto, Paulo A. Maia

    2018-03-01

    We consider an atom in its ground state undergoing a nonrelativistic oscillation in free space. The interaction with the electromagnetic quantum vacuum leads to two effects to leading order in perturbation theory. When the mechanical frequency is larger than the atomic transition frequency, the dominant effect is the motion-induced transition to an excited state with the emission of a photon carrying the excess energy. We compute the angular distribution of emitted photons and the excitation rate. On the other hand, when the mechanical frequency is smaller than the transition frequency, the leading-order effect is the parametric emission of photon pairs, which constitutes the microscopic counterpart of the dynamical Casimir effect. We discuss the properties of the microscopic dynamical Casimir effect and build a connection with the photon production by an oscillating macroscopic metallic mirror.

  14. [Modern methods of balneotherapy of digestive pathology at the Caucasian Mineral Waters spa-and-resort complex].

    Science.gov (United States)

    Kaĭsinova, A S; Efimenko, N V; Babiakin, A F; Grinzaĭd, Iu M; Osipov, Iu S

    2010-01-01

    Scientists of Pyatigorsky State Research Institute of Balneotherapeutics are actively engaged in developing new medical technologies for rehabilitative treatment of patients with a variety of pathological conditions based on the current knowledge about mechanisms of action of natural therapeutic factors. Most of these original methods are included in the State Inventory of novel medical technologies by the Federal Supervisory Health and Social Development Service. The proposed medical technologies based on the application of natural and man-made physical factors improved general effect of balneotherapy by 15-20% and accelerated recovery from the disease. Specifically, the length of post-treatment remission increased to 7-12 months and duration of temporary disability decreased 2.5-3 times. Sick list payouts and economic expenditures of the state and the patients for medicinal preparations were reduced 3-4-fold while the quality of life and clinical prognosis significantly improved.

  15. Color Laser Microscope

    Science.gov (United States)

    Awamura, D.; Ode, T.; Yonezawa, M.

    1987-04-01

    A color laser microscope utilizing a new color laser imaging system has been developed for the visual inspection of semiconductors. The light source, produced by three lasers (Red; He-Ne, Green; Ar, Blue; He-Cd), is deflected horizontally by an AOD (Acoustic Optical Deflector) and vertically by a vibration mirror. The laser beam is focused in a small spot which is scanned over the sample at high speed. The light reflected back from the sample is reformed to contain linear information by returning to the original vibration mirror. The linear light is guided to the CCD image sensor where it is converted into a video signal. Individual CCD image sensors are used for each of the three R, G, or B color image signals. The confocal optical system with its laser light source yields a color TV monitor image with no flaring and a much sharper resolution than that of the conventional optical microscope. The AOD makes possible a high speed laser scan and a NTSC or PAL TV video signal is produced in real time without any video memory. Since the light source is composed of R, G, and B laser beams, color separation superior to that of white light illumination is achieved. Because of the photometric linearity of the image detector, the R, G, and B outputs of the system are most suitably used for hue analysis. The CCD linear image sensors in the optical system produce no geometrical distortion, and good color registration is available principally. The output signal can be used for high accuracy line width measuring. The many features of the color laser microscope make it ideally suited for the visual inspection of semiconductor processing. A number of these systems have already been installed in such a capacity. The Color Laser Microscope can also be a very useful tool for the fields of material engineering and biotechnology.

  16. Virtual pinhole confocal microscope

    Energy Technology Data Exchange (ETDEWEB)

    George, J.S.; Rector, D.M.; Ranken, D.M. [Los Alamos National Lab., NM (United States). Biophysics Group; Peterson, B. [SciLearn Inc. (United States); Kesteron, J. [VayTech Inc. (United States)

    1999-06-01

    Scanned confocal microscopes enhance imaging capabilities, providing improved contrast and image resolution in 3-D, but existing systems have significant technical shortcomings and are expensive. Researchers at Los Alamos National Laboratory have developed a novel approach--virtual pinhole confocal microscopy--that uses state of the art illumination, detection, and data processing technologies to produce an imager with a number of advantages: reduced cost, faster imaging, improved efficiency and sensitivity, improved reliability and much greater flexibility. Work at Los Alamos demonstrated proof of principle; prototype hardware and software have been used to demonstrate technical feasibility of several implementation strategies. The system uses high performance illumination, patterned in time and space. The authors have built functional confocal imagers using video display technologies (LCD or DLP) and novel scanner based on a micro-lens array. They have developed a prototype system for high performance data acquisition and processing, designed to support realtime confocal imaging. They have developed algorithms to reconstruct confocal images from a time series of spatially sub-sampled images; software development remains an area of active development. These advances allow the collection of high quality confocal images (in fluorescence, reflectance and transmission modes) with equipment that can inexpensively retrofit to existing microscopes. Planned future extensions to these technologies will significantly enhance capabilities for microscopic imaging in a variety of applications, including confocal endoscopy, and confocal spectral imaging.

  17. Quantitative research on microscopic deformation behavior of Ti-6Al-4V two-phase titanium alloy based on finite element method

    Science.gov (United States)

    Peng, Yan; Chen, Guoxing; Sun, Jianliang; Shi, Baodong

    2018-04-01

    The microscopic deformation of Ti-6Al-4V titanium alloy shows great inhomogeneity due to its duplex-microstructure that consists of two phases. In order to study the deformation behaviors of the constituent phases, the 2D FE model based on the realistic microstructure is established by MSC.Marc nonlinear FE software, and the tensile simulation is carried out. The simulated global stress-strain response is confirmed by the tensile testing result. Then the strain and stress distribution in the constituent phases and their evolution with the increase of the global strain are analyzed. The results show that the strain and stress partitioning between the two phases are considerable, most of the strain is concentrated in soft primary α phase, while hard transformed β matrix undertakes most of the stress. Under the global strain of 0.05, the deformation bands in the direction of 45° to the stretch direction and the local stress in primary α phase near to the interface between the two phases are observed, and they become more significant when the global strain increases to 0.1. The strain and stress concentration factors of the two phases are obviously different at different macroscopic deformation stages, but they almost tend to be stable finally.

  18. Occupational concerns associated with regular use of microscope

    Directory of Open Access Journals (Sweden)

    Garima Jain

    2014-08-01

    Full Text Available Objectives: Microscope work can be strenuous both to the visual system and the musculoskeletal system. Lack of awareness or indifference towards health issues may result in microscope users becoming victim to many occupational hazards. Our objective was to understand the occupational problems associated with regular use of microscope, awareness regarding the hazards, attitude and practice of microscope users towards the problems and preventive strategies. Material and Methods: A questionnaire based survey done on 50 professionals and technicians who used microscope regularly in pathology, microbiology, hematology and cytology laboratories. Results: Sixty two percent of subjects declared that they were suffering from musculoskeletal problems, most common locations being neck and back. Maximum prevalence of musculoskeletal problems was noted in those using microscope for 11–15 years and for more than 30 h/week. Sixty two percent of subjects were aware of workplace ergonomics. Fifty six percent of microscope users took regular short breaks for stretching exercises and 58% took visual breaks every 15–30 min in between microscope use sessions. As many as 94% subjects reported some form of visual problem. Fourty four percent of microscope users felt stressed with long working hours on microscope. Conclusions: The most common occupational concerns of microscope users were musculoskeletal problems of neck and back regions, eye fatigue, aggravation of ametropia, headache, stress due to long working hours and anxiety during or after microscope use. There is an immediate need for increasing awareness about the various occupational hazards and their irreversible effects to prevent them.

  19. A molecular method to assess bioburden embedded within silicon-based resins used on modern spacecraft materials

    Science.gov (United States)

    Stam, Christina N.; Bruckner, James; Spry, J. Andy; Venkateswaran, Kasthuri; La Duc, Myron T.

    2012-07-01

    Current assessments of bioburden embedded in spacecraft materials are based on work performed in the Viking era (1970s), and the ability to culture organisms extracted from such materials. To circumvent the limitations of such approaches, DNA-based techniques were evaluated alongside established culturing techniques to determine the recovery and survival of bacterial spores encapsulated in spacecraft-qualified polymer materials. Varying concentrations of Bacillus pumilus SAFR-032 spores were completely embedded in silicone epoxy. An organic dimethylacetamide-based solvent was used to digest the epoxy and spore recovery was evaluated via gyrB-targeted qPCR, direct agar plating, most probably number analysis, and microscopy. Although full-strength solvent was shown to inhibit the germination and/or outgrowth of spores, dilution in excess of 100-fold allowed recovery with no significant decrease in cultivability. Similarly, qPCR (quantitative PCR) detection sensitivities as low as ~103 CFU ml-1 were achieved upon removal of inhibitory substances associated with the epoxy and/or solvent. These detection and enumeration methods show promise for use in assessing the embedded bioburden of spacecraft hardware.

  20. Cobol software modernization

    CERN Document Server

    Barbier, Franck

    2015-01-01

    Nowadays, billions of lines of code are in the COBOL programming language. This book is an analysis, a diagnosis, a strategy, a MDD method and a tool to transform legacy COBOL into modernized applications that comply with Internet computing, Service-Oriented Architecture (SOA) and the Cloud.  It serves as a blueprint for those in charge of finding solutions to this considerable challenge.

  1. Savremene metode analize ulja u tehničkim sistemima / Modern methods of oil analysis in technical systems

    Directory of Open Access Journals (Sweden)

    Sreten R. Perić

    2010-01-01

    Full Text Available Analiza ulja na osnovu pravilno definisanog programa predstavlja veoma efikasan metod monitoringa stanja tehničkih sistema koji obezbeđuje rane upozoravajuće znake potencijalnih problema, koji vode ka otkazu i zastoju tehničkih sistema. Ova analiza je veoma efikasan alat programa za monitoring stanja tehničkih sistema. Mnogobrojni uređaji i testovi za analizu ulja omogućavaju kvalitetan monitoring i dijagnosticiranje problema koji nastaju u procesu podmazivanja. Korišćenjem programa za analizu motornih ulja: skraćuje se neplanirano vreme otkaza vozila, poboljšava pouzdanost vozila, produžava radni vek motora, optimizira interval zamene ulja i smanjuju troškovi održavanja vozila. / Different technical systems require an appropriate lubricant to be used at an appropriate place, at appropriate time and in appropriate quantity. Determination of technical systems condition has a very important role in the development of theory and practice of friction, wear and lubrication. Lubricant is, as a contact element of tribomechanical systems, a carrier of information about the state of the whole system, from the aspect of tribological and other ageing processes. The analysis of oils, based on a properly defined program, thus represents a very effective method for monitoring the condition of technical systems, which ensures early warning signals of potential problems that could lead to failure and break down of technical systems. Introduction It is not always simple to determine a type of lubricant, frequency of lubrication and the quantity of lubricant to be used. The optimal recommendation would be to follow specifications of technical system manufacturers, experience, lab research or professional recommendation of lubricant suppliers. Rational lubricant consumption can be obtained by timely oil replacement, which then enables a maximum possible period of use as well as high-quality lubrication. Since the primary role of lubricants is to

  2. A step towards standardization: A method for end-point titer determination by fluorescence index of an automated microscope. End-point titer determination by fluorescence index.

    Science.gov (United States)

    Carbone, Teresa; Gilio, Michele; Padula, Maria Carmela; Tramontano, Giuseppina; D'Angelo, Salvatore; Pafundi, Vito

    2018-05-01

    Indirect Immunofluorescence (IIF) is widely considered the Gold Standard for Antinuclear Antibody (ANA) screening. However, the high inter-reader variability remains the major disadvantage associated with ANA testing and the main reason for the increasing demand of the computer-aided immunofluorescence microscope. Previous studies proposed the quantification of the fluorescence intensity as an alternative for the classical end-point titer evaluation. However, the different distribution of bright/dark light linked to the nature of the self-antigen and its location in the cells result in different mean fluorescence intensities. The aim of the present study was to correlate Fluorescence Index (F.I.) with end-point titers for each well-defined ANA pattern. Routine serum samples were screened for ANA testing on HEp-2000 cells using Immuno Concepts Image Navigator System, and positive samples were serially diluted to assign the end-point titer. A comparison between F.I. and end-point titers related to 10 different staining patterns was made. According to our analysis, good technical performance of F.I. (97% sensitivity and 94% specificity) was found. A significant correlation between quantitative reading of F.I. and end-point titer groups was observed using Spearman's test and regression analysis. A conversion scale of F.I. in end-point titers for each recognized ANA-pattern was obtained. The Image Navigator offers the opportunity to improve worldwide harmonization of ANA test results. In particular, digital F.I. allows quantifying ANA titers by using just one sample dilution. It could represent a valuable support for the routine laboratory and an effective tool to reduce inter- and intra-laboratory variability. Copyright © 2018. Published by Elsevier B.V.

  3. IMIS: An intelligence microscope imaging system

    Science.gov (United States)

    Caputo, Michael; Hunter, Norwood; Taylor, Gerald

    1994-01-01

    Until recently microscope users in space relied on traditional microscopy techniques that required manual operation of the microscope and recording of observations in the form of written notes, drawings, or photographs. This method was time consuming and required the return of film and drawings from space for analysis. No real-time data analysis was possible. Advances in digital and video technologies along with recent developments in article intelligence will allow future space microscopists to have a choice of three additional modes of microscopy: remote coaching, remote control, and automation. Remote coaching requires manual operations of the microscope with instructions given by two-way audio/video transmission during critical phases of the experiment. When using the remote mode of microscopy, the Principal Investigator controls the microscope from the ground. The automated mode employs artificial intelligence to control microscope functions and is the only mode that can be operated in the other three modes as well. The purpose of this presentation is to discuss the advantages and disadvantages of the four modes of of microscopy and how the IMIS, a proposed intelligent microscope imaging system, can be used as a model for developing and testing concepts, operating procedures, and equipment design of specifications required to provide a comprehensive microscopy/imaging capability onboard Space Station Freedom.

  4. Atomic Force Microscope

    Energy Technology Data Exchange (ETDEWEB)

    Day, R.D.; Russell, P.E.

    1988-12-01

    The Atomic Force Microscope (AFM) is a recently developed instrument that has achieved atomic resolution imaging of both conducting and non- conducting surfaces. Because the AFM is in the early stages of development, and because of the difficulty of building the instrument, it is currently in use in fewer than ten laboratories worldwide. It promises to be a valuable tool for obtaining information about engineering surfaces and aiding the .study of precision fabrication processes. This paper gives an overview of AFM technology and presents plans to build an instrument designed to look at engineering surfaces.

  5. Solid state optical microscope

    Science.gov (United States)

    Young, Ian T.

    1983-01-01

    A solid state optical microscope wherein wide-field and high-resolution images of an object are produced at a rapid rate by utilizing conventional optics with a charge-coupled photodiode array. A galvanometer scanning mirror, for scanning in one of two orthogonal directions is provided, while the charge-coupled photodiode array scans in the other orthogonal direction. Illumination light from the object is incident upon the photodiodes, creating packets of electrons (signals) which are representative of the illuminated object. The signals are then processed, stored in a memory, and finally displayed as a video signal.

  6. 论古代医德教育方法及其现代意义%The Ancient Medical Ethics Education Method and Its Modern Significance

    Institute of Scientific and Technical Information of China (English)

    艾华; 唐宇平; 刘钊; 郭辉; 谷晓红

    2013-01-01

    In order to explore and improve the method of medical ethics education,this paper reviewed the three categories of ancient medical ethics education method,namely the theory of medical discipline and edification,biographies' acknowledgement and leading role,teacher teaching students mode,aimed to provide basis and reference for modern medical ethics education,in order to improve the effectiveness of medical ethics education of medical colleges and to improve medical students medical ethics education level.%为了改进医德教育方法,通过对三大类古代医德教育方法的概述,医戒医论的灌输熏陶、医家传记的榜样表率、师徒相授的言传身教,为现代医德教育提供依据和参考,以提高医学院校医德教育的效果,促使医学生提高医德修养水平.

  7. Scanning microscopic four-point conductivity probes

    DEFF Research Database (Denmark)

    Petersen, Christian Leth; Hansen, Torben Mikael; Bøggild, Peter

    2002-01-01

    A method for fabricating microscopic four-point probes is presented. The method uses silicon-based microfabrication technology involving only two patterning steps. The last step in the fabrication process is an unmasked deposition of the conducting probe material, and it is thus possible to select...... the conducting material either for a silicon wafer or a single probe unit. Using shadow masking photolithography an electrode spacing (pitch) down to 1.1 mum was obtained, with cantilever separation down to 200 run. Characterisation measurements have shown the microscopic probes to be mechanically very flexible...

  8. Modern water resources engineering

    CERN Document Server

    Yang, Chih

    2014-01-01

    The Handbook of Environmental Engineering series is an incredible collection of methodologies that study the effects of pollution and waste in their three basic forms: gas, solid, and liquid. This exciting new addition to the series, Volume 15: Modern Water Resources Engineering , has been designed to serve as a water resources engineering reference book as well as a supplemental textbook. We hope and expect it will prove of equal high value to advanced undergraduate and graduate students, to designers of water resources systems, and to scientists and researchers. A critical volume in the Handbook of Environmental Engineering series, chapters employ methods of practical design and calculation illustrated by numerical examples, include pertinent cost data whenever possible, and explore in great detail the fundamental principles of the field. Volume 15: Modern Water Resources Engineering, provides information on some of the most innovative and ground-breaking advances in the field today from a panel of esteemed...

  9. Modern methods of personnel dosimetry

    International Nuclear Information System (INIS)

    Kraus, W.; Herrmann, D.; Kiesewetter, W.

    The physical properties of radiation detectors for personnel dosimetry are described and compared. The suitability of different types of dosimeters for operational and central monitoring of normal occupational exposure, for accident and catastrophe dosimetry and for background and space-flight dosimetry is discussed. The difficulties in interpreting the dosimeter reading with respect to the dose in individual body organs are discussed briefly. 430 literature citations (up to Spring 1966) are given

  10. Modern methods for radiostrontium determination

    International Nuclear Information System (INIS)

    Grahek, Z.; Kosutic, K.; Lulic, S.

    1998-01-01

    The basic principles of the ion exchange chromatographic determination of radioactive strontium in liquid wastes and natural samples are presented. The sample is inserted into the chromatographic column through the injection system connected to a pump. Strontium is separated by column elution. A flow scintillation beta detector is positioned at the column outlet. Prior to entering the column, strontium is mixed with a scintillator. The apparatus for semi-automatic radiostrontium determination is also described. (M.D.)

  11. GROUPWARE - MODERN INFORMATION MANAGERIAL METHOD

    Directory of Open Access Journals (Sweden)

    Rozalia NISTOR

    2006-01-01

    Full Text Available The notion groupware contents the information technologies that facilitate theteam work and that are intended for communication, collaboration,coordination within the organization. Having as base software routines forteamwork, the groupware technology has many applications in themanagement process of the organization. The notion groupware refers to aspecial class of web packages connected to a network of personalcomputers: email, chat, video IP, newsgroups, etc. The studies from theliterature consider the groupware as a class of software programs thatfacilitate the coordination, the communication and the cooperation within themember of a group. As in marketing the marketing-mix is known as the “4P”,in the area of groupware its characteristics are known as the “3C”:communication within the group; coordination among the members of thegroup; collaboration among the members of the group. From the groupwaresoftware those with relevance for the managerial activity are: electronic mail,Internet meetings, time management, project management, the managementof dissimulated information. The groupware technologies can be divised inmany categories based on two elements: time and space. The users of agroupware work together in the same time – real time groupware, or invarious periods of time – offline groupware.

  12. Multiple modernities, modern subjectivities and social order

    DEFF Research Database (Denmark)

    Jung, Dietrich; Sinclair, Kirstine

    2015-01-01

    to modern subjectivity formation. In combining conceptual tools from these strands of social theory, we argue that the emergence of multiple modernities should be understood as a historical result of idiosyncratic social constructions combining global social imaginaries with religious and other cultural......Taking its point of departure in the conceptual debate about modernities in the plural, this article presents a heuristic framework based on an interpretative approach to modernity. The article draws on theories of multiple modernities, successive modernities and poststructuralist approaches...... traditions. In the second part of the article we illustrate this argument with three short excursions into the history of Islamic reform in the 19th and 20th centuries. In this way we interpret the modern history of Muslim societies as based on cultural conflicts between different forms of social order...

  13. Electron microscope phase enhancement

    Science.gov (United States)

    Jin, Jian; Glaeser, Robert M.

    2010-06-15

    A microfabricated electron phase shift element is used for modifying the phase characteristics of an electron beam passing though its center aperture, while not affecting the more divergent portion of an incident beam to selectively provide a ninety-degree phase shift to the unscattered beam in the back focal plan of the objective lens, in order to realize Zernike-type, in-focus phase contrast in an electron microscope. One application of the element is to increase the contrast of an electron microscope for viewing weakly scattering samples while in focus. Typical weakly scattering samples include biological samples such as macromolecules, or perhaps cells. Preliminary experimental images demonstrate that these devices do apply a ninety degree phase shift as expected. Electrostatic calculations have been used to determine that fringing fields in the region of the scattered electron beams will cause a negligible phase shift as long as the ratio of electrode length to the transverse feature-size aperture is about 5:1. Calculations are underway to determine the feasibility of aspect smaller aspect ratios of about 3:1 and about 2:1.

  14. Forensic Scanning Electron Microscope

    Science.gov (United States)

    Keeley, R. H.

    1983-03-01

    The scanning electron microscope equipped with an x-ray spectrometer is a versatile instrument which has many uses in the investigation of crime and preparation of scientific evidence for the courts. Major applications include microscopy and analysis of very small fragments of paint, glass and other materials which may link an individual with a scene of crime, identification of firearms residues and examination of questioned documents. Although simultaneous observation and chemical analysis of the sample is the most important feature of the instrument, other modes of operation such as cathodoluminescence spectrometry, backscattered electron imaging and direct x-ray excitation are also exploited. Marks on two bullets or cartridge cases can be compared directly by sequential scanning with a single beam or electronic linkage of two instruments. Particles of primer residue deposited on the skin and clothing when a gun is fired can be collected on adhesive tape and identified by their morphology and elemental composition. It is also possible to differentiate between the primer residues of different types of ammunition. Bullets may be identified from the small fragments left behind as they pass through the body tissues. In the examination of questioned documents the scanning electron microscope is used to establish the order in which two intersecting ink lines were written and to detect traces of chemical markers added to the security inks on official documents.

  15. Active Mask Segmentation of Fluorescence Microscope Images

    OpenAIRE

    Srinivasa, Gowri; Fickus, Matthew C.; Guo, Yusong; Linstedt, Adam D.; Kovačević, Jelena

    2009-01-01

    We propose a new active mask algorithm for the segmentation of fluorescence microscope images of punctate patterns. It combines the (a) flexibility offered by active-contour methods, (b) speed offered by multiresolution methods, (c) smoothing offered by multiscale methods, and (d) statistical modeling offered by region-growing methods into a fast and accurate segmentation tool. The framework moves from the idea of the “contour” to that of “inside and outside”, or, masks, allowing for easy mul...

  16. Microscopic saw mark analysis: an empirical approach.

    Science.gov (United States)

    Love, Jennifer C; Derrick, Sharon M; Wiersema, Jason M; Peters, Charles

    2015-01-01

    Microscopic saw mark analysis is a well published and generally accepted qualitative analytical method. However, little research has focused on identifying and mitigating potential sources of error associated with the method. The presented study proposes the use of classification trees and random forest classifiers as an optimal, statistically sound approach to mitigate the potential for error of variability and outcome error in microscopic saw mark analysis. The statistical model was applied to 58 experimental saw marks created with four types of saws. The saw marks were made in fresh human femurs obtained through anatomical gift and were analyzed using a Keyence digital microscope. The statistical approach weighed the variables based on discriminatory value and produced decision trees with an associated outcome error rate of 8.62-17.82%. © 2014 American Academy of Forensic Sciences.

  17. Basics of modern mathematical statistics

    CERN Document Server

    Spokoiny, Vladimir

    2015-01-01

    This textbook provides a unified and self-contained presentation of the main approaches to and ideas of mathematical statistics. It collects the basic mathematical ideas and tools needed as a basis for more serious studies or even independent research in statistics. The majority of existing textbooks in mathematical statistics follow the classical asymptotic framework. Yet, as modern statistics has changed rapidly in recent years, new methods and approaches have appeared. The emphasis is on finite sample behavior, large parameter dimensions, and model misspecifications. The present book provides a fully self-contained introduction to the world of modern mathematical statistics, collecting the basic knowledge, concepts and findings needed for doing further research in the modern theoretical and applied statistics. This textbook is primarily intended for graduate and postdoc students and young researchers who are interested in modern statistical methods.

  18. A budget impact analysis comparing use of a modern fecal management system to traditional fecal management methods in two canadian hospitals.

    Science.gov (United States)

    Langill, Mike; Yan, Songkai; Kommala, Dheerendra; Michenko, Michael

    2012-12-01

    Research suggests that fecal management systems (FMS) offer advantages, including potential cost savings, over traditional methods of caring for patients with little or no bowel control and liquid or semi-liquid stool. A budget impact model accounting for material costs of managing fecal incontinence was developed, and 1 year of experiential data from two hospitals' ICUs were applied to it. Material costs were estimated for traditional methods (ie, use of absorbent briefs/pads, skin cleansers, moisturizers) and compared with material costs of using a modern FMS for both average (normal-range weight) and complex (bariatric with wounds) ICU patients at hospital 1 and any ICU patient at hospital 2. Reductions in daily material costs per ICU patient using FMS versus traditional methods were reported by hospital 1 ($93.74 versus $143.89, average patient; $150.55 versus $476.41, complex patient) and by hospital 2 ($61.15 versus $104.85 per patient). When extrapolated to the total number of patients expected to use FMS at each institution, substantial annual cost savings were projected (hospital 1: $57,216; hospital 2: $627,095). In addition, total nursing time per day for managing fecal incontinence (ie, changing, cleaning, repositioning patients, changing pads, linens, and the like) was estimated at hospital 1, showing substantial reductions with FMS (120 minutes versus 348 minutes for average patients; 240 minutes versus 760 minutes for complex). Nursing time was not included in cost calculations to keep the analysis conservative. Results of this study suggest the materials cost of using the FMS in ICU patients was substantially lower than the cost of traditional fecal incontinence management protocols of care in both hospitals. Comparative studies using patient level data, materials, and nursing time costs, as well as complication rates, are warranted.

  19. Imaging arrangement and microscope

    Science.gov (United States)

    Pertsinidis, Alexandros; Chu, Steven

    2015-12-15

    An embodiment of the present invention is an imaging arrangement that includes imaging optics, a fiducial light source, and a control system. In operation, the imaging optics separate light into first and second tight by wavelength and project the first and second light onto first and second areas within first and second detector regions, respectively. The imaging optics separate fiducial light from the fiducial light source into first and second fiducial light and project the first and second fiducial light onto third and fourth areas within the first and second detector regions, respectively. The control system adjusts alignment of the imaging optics so that the first and second fiducial light projected onto the first and second detector regions maintain relatively constant positions within the first and second detector regions, respectively. Another embodiment of the present invention is a microscope that includes the imaging arrangement.

  20. Microscopic entropy and nonlocality

    International Nuclear Information System (INIS)

    Karpov, E.; Ordonets, G.; Petroskij, T.; Prigozhin, I.

    2003-01-01

    We have obtained a microscopic expression for entropy in terms of H function based on nonunitary Λ transformation which leads from the time evolution as a unitary group to a Markovian dynamics and unifies the reversible and irreversible aspects of quantum mechanics. This requires a new representation outside the Hilbert space. In terms of H, we show the entropy production and the entropy flow during the emission and absorption of radiation by an atom. Analyzing the time inversion experiment, we emphasize the importance of pre- and postcollisional correlations, which break the symmetry between incoming and outgoing waves. We consider the angle dependence of the H function in a three-dimensional situation. A model including virtual transitions is discussed in a subsequent paper

  1. Microscopic cross-section measurements by thermal neutron activation

    International Nuclear Information System (INIS)

    Avila L, J.

    1987-08-01

    Microscopic cross sections measured by thermal neutron activation using RP-0 reactor at the Peruvian Nuclear Energy Institute. The method consists in measuring microscopic cross section ratios through activated samples, requiring being corrected in thermal and epithermal energetic range by Westcott formalism. Furthermore, the comptage ratios measured for each photopeak to its decay fraction should be normalized from interrelation between both processes above, activation microscopic cross sections are obtained

  2. A modern method of treatment: The role of silver dressings in promoting healing and preventing pathological scarring in patients with burn wounds

    Science.gov (United States)

    Munteanu, A; Florescu, IP; Nitescu, C

    2016-01-01

    Burn wounds are a global public health problem, which affects all countries, no matter the development stage and occurs in all age groups, from toddlers to elderly. In spite of burns being the cause of numerous household and work accidents, there are still no clear stated unanimous rules for their treatment. Every day new products appear on the market, each of them trying to prove more effective. Since ancient times, silver has been known for its antimicrobial properties, so it has been used for a long time in the treatment of burns and other types of wounds. One of the relatively modern methods of treatment is applying silver sheets on the scald lesions. In this paper, which was part of a larger study (research for a PhD thesis), concerning prevention and treatment of the post-burn pathological scars, the cases of some patients with burns, who were treated by using the above mentioned method were presented and analyzed. The results obtained by applying silver sheets were then commented and interpreted, pointing out the advantages and disadvantages compared to silver sulfadiazine creams and ointments, which have already been used at a large scale. The prevention and treatment of post-burn pathological (hypertrophic and keloid) scars is a field in which still little is known and in which there are also no clearly set therapy plans. We hope that through this research and the following ones we will manage to establish some major guidelines concerning the prevention of pathological scars, which are not only disabling, but also a major aesthetic issue for any patient, in order to obtain better outcomes. PMID:27974941

  3. A protocol for pressurized liquid extraction and processing methods to isolate modern and ancient bone cholesterol for compound-specific stable isotope analysis.

    Science.gov (United States)

    Laffey, Ann O; Krigbaum, John; Zimmerman, Andrew R

    2017-02-15

    Bone lipid compound-specific isotope analysis (CSIA) and bone collagen and apatite stable isotope ratio analysis are important sources of ecological and paleodietary information. Pressurized liquid extraction (PLE) is quicker and utilizes less solvent than traditional methods of lipid extraction such as soxhlet and ultrasonication. This study facilitates dietary analysis by optimizing and testing a standardized methodology for PLE of bone cholesterol. Modern and archaeological bones were extracted by PLE using varied temperatures, solvent solutions, and sample weights. The efficiency of PLE was assessed via quantification of cholesterol yields. Stable isotopic ratio integrity was evaluated by comparing isotopic signatures (δ 13 C and δ 18 O values) of cholesterol derived from whole bone, bone collagen and bone apatite. Gas chromatography/mass spectrometry (GC/MS) and gas chromatography isotope ratio mass spectrometry (GC/IRMS) were conducted on purified collagen and lipid extracts to assess isotopic responses to PLE. Lipid yield was optimized at two PLE extraction cycles of 75 °C using dichloromethane/methanol (2:1 v/v) as a solvent with 0.25-0.75 g bone sample. Following lipid extraction, saponification combined with the derivatization of the neutral fraction using trimethylsilylation yielded nearly twice the cholesterol of non-saponified or non-derivatized samples. It was also found that lipids extracted from purified bone collagen and apatite could be used for cholesterol CSIA. There was no difference in the bulk δ 13 C values of collagen extracted from bone with or without lipid. However, there was a significant depletion in 18 O of bone apatite due to lipid presence or processing. These results should assist sample selection and provide an effective, alternative extraction method for bone cholesterol that may be used for isotopic and paleodietary analysis. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  4. Expectations for neutrons as microscopic probes

    International Nuclear Information System (INIS)

    Date, M.

    1993-01-01

    Neutrons have been used as microscopic probes to study structural and dynamical properties of various materials. In this paper I shall give a comparative study of the neutron research in the condensed matter physics with other typical microscopic methods such as X-rays, laser optics, magnetic resonances, Moessbauer effect and μSR. It is emphasized that the neutron study will extensively be important in future beyond the condensed matter physics. Chemistry, biology, earth sciences, material engineerings and medical sciences will become new frontiers for neutron study. (author)

  5. Exploring the environmental transmission electron microscope

    DEFF Research Database (Denmark)

    Wagner, Jakob B.; Cavalca, Filippo; Damsgaard, Christian D.

    2012-01-01

    of the opportunities that the environmental TEM (ETEM) offers when combined with other in situ techniques will be explored, directly in the microscope, by combining electron-based and photon-based techniques and phenomena. In addition, application of adjacent setups using sophisticated transfer methods...

  6. Femtosecond photoelectron point projection microscope

    International Nuclear Information System (INIS)

    Quinonez, Erik; Handali, Jonathan; Barwick, Brett

    2013-01-01

    By utilizing a nanometer ultrafast electron source in a point projection microscope we demonstrate that images of nanoparticles with spatial resolutions of the order of 100 nanometers can be obtained. The duration of the emission process of the photoemitted electrons used to make images is shown to be of the order of 100 fs using an autocorrelation technique. The compact geometry of this photoelectron point projection microscope does not preclude its use as a simple ultrafast electron microscope, and we use simple analytic models to estimate temporal resolutions that can be expected when using it as a pump-probe ultrafast electron microscope. These models show a significant increase in temporal resolution when comparing to ultrafast electron microscopes based on conventional designs. We also model the microscopes spectroscopic abilities to capture ultrafast phenomena such as the photon induced near field effect

  7. Optical modeling of Fresnel zoneplate microscopes

    International Nuclear Information System (INIS)

    Naulleau, Patrick P.; Mochi, Iacopo; Goldberg, Kenneth A.

    2011-01-01

    Defect free masks remain one of the most significant challenges facing the commercialization of extreme ultraviolet (EUV) lithography. Progress on this front requires high-performance wavelength-specific metrology of EUV masks, including high-resolution and aerial-image microscopy performed near the 13.5 nm wavelength. Arguably the most cost-effective and rapid path to proliferating this capability is through the development of Fresnel zoneplate-based microscopes. Given the relative obscurity of such systems, however, modeling tools are not necessarily optimized to deal with them and their imaging properties are poorly understood. Here we present a modeling methodology to analyze zoneplate microscopes based on commercially available optical modeling software and use the technique to investigate the imaging performance of an off-axis EUV microscope design. The modeling predicts that superior performance can be achieved by tilting the zoneplate, making it perpendicular to the chief ray at the center of the field, while designing the zoneplate to explicitly work in that tilted plane. Although the examples presented here are in the realm of EUV mask inspection, the methods described and analysis results are broadly applicable to zoneplate microscopes in general, including full-field soft-x-ray microscopes routinely used in the synchrotron community.

  8. Transmission electron microscope CCD camera

    Science.gov (United States)

    Downing, Kenneth H.

    1999-01-01

    In order to improve the performance of a CCD camera on a high voltage electron microscope, an electron decelerator is inserted between the microscope column and the CCD. This arrangement optimizes the interaction of the electron beam with the scintillator of the CCD camera while retaining optimization of the microscope optics and of the interaction of the beam with the specimen. Changing the electron beam energy between the specimen and camera allows both to be optimized.

  9. The efficiency of conventional microscopic selection is comparable to the hyaluronic acid binding method in selecting spermatozoa for male infertility patients

    OpenAIRE

    Meng-Ting Huang; Robert Kuo-Kuang Lee; Chung-Hao Lu; Ying-Jie Chen; Sheng-Hsiang Li; Yuh-Ming Hwu

    2015-01-01

    Objective: To evaluate if hyaluronic acid (HA)-bound spermatozoa surpassed conventional microscopy-selected spermatozoa in the status of sperm DNA integrity by acridine orange (AO) fluorescence staining. Materials and methods: Spermatozoa obtained from couples with indication for the intracytoplasmic sperm injection (ICSI) procedure due to male infertility (n = 34) and control males with normal sperm parameters (n = 12) were analyzed using AO fluorescence staining after density-gradient ce...

  10. A method for measuring the local gas pressure within a gas-flow stage in situ in the transmission electron microscope

    International Nuclear Information System (INIS)

    Colby, R.; Alsem, D.H.; Liyu, A.; Kabius, B.

    2015-01-01

    Environmental transmission electron microscopy (TEM) has enabled in situ experiments in a gaseous environment with high resolution imaging and spectroscopy. Addressing scientific challenges in areas such as catalysis, corrosion, and geochemistry can require pressures much higher than the ∼20 mbar achievable with a differentially pumped environmental TEM. Gas flow stages, in which the environment is contained between two semi-transparent thin membrane windows, have been demonstrated at pressures of several atmospheres. However, the relationship between the pressure at the sample and the pressure drop across the system is not clear for some geometries. We demonstrate a method for measuring the gas pressure at the sample by measuring the ratio of elastic to inelastic scattering and the defocus of the pair of thin windows. This method requires two energy filtered high-resolution TEM images that can be performed during an ongoing experiment, at the region of interest. The approach is demonstrated to measure greater than atmosphere pressures of N 2 gas using a commercially available gas-flow stage. This technique provides a means to ensure reproducible sample pressures between different experiments, and even between very differently designed gas-flow stages. - Highlights: • Method developed for measuring gas pressure within a gas-flow stage in the TEM. • EFTEM and CTF-fitting used to calculate amount and volume of gas. • Requires only a pair of images without leaving region of interest. • Demonstrated for P > 1 atm with a common commercial gas-flow stage

  11. Modern gear production

    CERN Document Server

    Watson, H J

    1970-01-01

    Modern Gear Production focuses on the processes and methods in gear making. The book first gives information on the history of gear making and types of gears. Topics such as the classification of gears based on the disposition of their shafts; shafts lying in the same plane with axes intersecting; and shafts lying in parallel planes but with axes inclined to one another are then discussed. The text describes gear groups, tooth forms, and gear materials. Heat treatment of steels, casehardening, nitriding, induction hardening, sulfinuzing, and flame hardening are explained. The book takes a look

  12. Scanning Electron Microscope Analysis System

    Data.gov (United States)

    Federal Laboratory Consortium — This facility provides the capability to examine surfaces microscopically with high resolution (5 nanometers), perform micro chemical analyses of these surfaces, and...

  13. Microscopic to macroscopic depletion model development for FORMOSA-P

    International Nuclear Information System (INIS)

    Noh, J.M.; Turinsky, P.J.; Sarsour, H.N.

    1996-01-01

    Microscopic depletion has been gaining popularity with regard to employment in reactor core nodal calculations, mainly attributed to the superiority of microscopic depletion in treating spectral history effects during depletion. Another trend is the employment of loading pattern optimization computer codes in support of reload core design. Use of such optimization codes has significantly reduced design efforts to optimize reload core loading patterns associated with increasingly complicated lattice designs. A microscopic depletion model has been developed for the FORMOSA-P pressurized water reactor (PWR) loading pattern optimization code. This was done for both fidelity improvements and to make FORMOSA-P compatible with microscopic-based nuclear design methods. Needless to say, microscopic depletion requires more computational effort compared with macroscopic depletion. This implies that microscopic depletion may be computationally restrictive if employed during the loading pattern optimization calculation because many loading patterns are examined during the course of an optimization search. Therefore, the microscopic depletion model developed here uses combined models of microscopic and macroscopic depletion. This is done by first performing microscopic depletions for a subset of possible loading patterns from which 'collapsed' macroscopic cross sections are obtained. The collapsed macroscopic cross sections inherently incorporate spectral history effects. Subsequently, the optimization calculations are done using the collapsed macroscopic cross sections. Using this approach allows maintenance of microscopic depletion level accuracy without substantial additional computing resources

  14. The new Isidore microscope

    International Nuclear Information System (INIS)

    Rabouille, O.; Viard, J.; Menard, M.; Allegre, S.

    2001-01-01

    In the frame of the refurbishment of LECI hot laboratory in Saclay, it was decided to renew one of the two metallography lines of the building. This line is located at one end of the Isidore line of lead-shielded hot cells. The work started by the cleaning of 5 aout of 9 cells in Isidore line. Two were 2 m x 1.5 m cells, whereas the 3 others were smaller. Decontamination was difficult in both larger cells, because a lot of metallographic preparation had been performed there and because the cleaning of the lower parts of the cell, below the working area, was uneasy by remote manipulators. The refurbishment of the cells included: - Changing the windows, because old windows were made of glass panels sperated by oil, which is now prohibited by safety requirements. - Putting of a new pair of manipulators on one large cell, and adding bootings on manipulators on one large cell, and adding bootings on manipulators on both large cells. - Changing all the ventilation systems in these cells (new types of filters, new air-ducts), - Modifying and changing metallic pieces constituting the working are inside the cell - Increasing the hight of the small cells in order to add a manipulator for charging the sample on microscope or on hardness machine. - Simplifying the electrical wiring in order to decrease the fire risk in the hot cell line. - Add a better fire protection between the working area and the transfer area, i. e. between the front and the rear part of the cells. The scientific equipments fot these cells are: An Olympus microscope, modified by Optique Peter (company based in Lyons), equipped with a motorised sample holder (100 x 200 mm), maximum size of sample: O. D.=100 mm, 6 magnifications: x 12.5, x50, x100, x200, x500 and x1000, two microhardness positions: Vickers and Knoop. Polaroid image and digital camera with SIS image analysis system. A new periscope manufactured by Optique Peter. magnification x2 and x9, digital image and SIS system, and old periscope

  15. Sulfide silver architectonics of rat, cat, and guinea pig spinal cord. A light microscopic study with Timm's method for demonstration of heavy metals

    DEFF Research Database (Denmark)

    Schroder, H D

    1977-01-01

    The distribution of heavy metals in the spinal cord of the cat, rat, and guinea pig has been studied histochemically with Timm's sulfide silver method. There was considerable variation in the degree of staining of the neuropil. The dorsal horn showed a laminar staining pattern corresponding...... to the cytoarchitectonic lamination. Lamina I in the cat and guinea pig was light. Lamina II in all three species was heavily stained. In the rat and guinea pig it could be subdivided in a ventral and a dorsal layer, and moreover in the rat a darkly staining borderzone abutting on lamina III was present. Lamina III......, characterized by heterogeneous staining, also appeared dark, although less obvious in the guinea pig. In the ventral horn the coarser stained particles in lamina IX contrasted with the surrounding lamina. Cell staining varied between different cell groups, and within single cell populations. In the cat thoracic...

  16. Infrared up-conversion microscope

    DEFF Research Database (Denmark)

    2014-01-01

    There is presented an up-conversion infrared microscope (110) arranged for imaging an associated object (130), wherein the up-conversion infrared microscope (110) comprises a non-linear crystal (120) arranged for up-conversion of infrared electromagnetic radiation, and wherein an objective optical...

  17. Microscopic Simulation of Particle Detectors

    CERN Document Server

    Schindler, Heinrich

    Detailed computer simulations are indispensable tools for the development and optimization of modern particle detectors. The interaction of particles with the sensitive medium, giving rise to ionization or excitation of atoms, is stochastic by its nature. The transport of the resulting photons and charge carriers, which eventually generate the observed signal, is also subject to statistical fluctuations. Together with the readout electronics, these processes - which are ultimately governed by the atomic cross-sections for the respective interactions - pose a fundamental limit to the achievable detector performance. Conventional methods for calculating electron drift lines based on macroscopic transport coefficients used to provide an adequate description for traditional gas-based particle detectors such as wire chambers. However, they are not suitable for small-scale devices such as micropattern gas detectors, which have significantly gained importance in recent years. In this thesis, a novel approach, bas...

  18. Institutions and Modernity

    Directory of Open Access Journals (Sweden)

    Witold Morawski

    2013-09-01

    Full Text Available Purpose: Modernity consists of many confl icting aspects: It brings many empty promises, yet has resulted in new institutions that create bridges between the values and interests of millions of people who seek freedom, prosperity, quality of life, strengthened democracy and social justice. In this paper I attempt to a gain and loss account against modernity, because institutional rules are not only conducive to cooperative interactions, but to hostile interactions as well. People are not always guided by moral commitment, but rather more often driven by cold calculation or coercion.Methodology: Modernity has at least three defi nitions. The fi rst defi nition is based on ideas that took over the imagination of the era. The second defi nition is based on an analysis of the behavior of people who respond to reason as well as emotion and believe that they act more rationally than their ancestors or the traditional “others”. The third defi nition is the one closest to my heart, consisting of the use of institutional categories. Institutions offer practical ways of connecting ideas and people. The challenge for them is the result of deepening local and national interdependencies, but increasingly often also regional (e.g. European and global. Interdependencies are the result of the scientifi c and technological revolution, global markets, global governance mechanisms, the emergence of new social forces and cultural confl icts (against the background of reconciling identity and differences.Conclusions: The most important task is to identify the mechanisms of complex systems so that people know how to act under conditions of uncertainty, risk and crisis. Hence, the expectations toward institutions often exceed their abilities. Even though new institutions are being created and old ones are being fixed, we are witnessing and participating in, institutional paralysis and the decay (e.g. corruption. In this situation, it is imperative not only to

  19. Seamless stitching of tile scan microscope images.

    Science.gov (United States)

    Legesse, F B; Chernavskaia, O; Heuke, S; Bocklitz, T; Meyer, T; Popp, J; Heintzmann, R

    2015-06-01

    For diagnostic purposes, optical imaging techniques need to obtain high-resolution images of extended biological specimens in reasonable time. The field of view of an objective lens, however, is often smaller than the sample size. To image the whole sample, laser scanning microscopes acquire tile scans that are stitched into larger mosaics. The appearance of such image mosaics is affected by visible edge artefacts that arise from various optical aberrations which manifest in grey level jumps across tile boundaries. In this contribution, a technique for stitching tiles into a seamless mosaic is presented. The stitching algorithm operates by equilibrating neighbouring edges and forcing the brightness at corners to a common value. The corrected image mosaics appear to be free from stitching artefacts and are, therefore, suited for further image analysis procedures. The contribution presents a novel method to seamlessly stitch tiles captured by a laser scanning microscope into a large mosaic. The motivation for the work is the failure of currently existing methods for stitching nonlinear, multimodal images captured by our microscopic setups. Our method eliminates the visible edge artefacts that appear between neighbouring tiles by taking into account the overall illumination differences among tiles in such mosaics. The algorithm first corrects the nonuniform brightness that exists within each of the tiles. It then compensates for grey level differences across tile boundaries by equilibrating neighbouring edges and forcing the brightness at the corners to a common value. After these artefacts have been removed further image analysis procedures can be applied on the microscopic images. Even though the solution presented here is tailored for the aforementioned specific case, it could be easily adapted to other contexts where image tiles are assembled into mosaics such as in astronomical or satellite photos. © 2015 The Authors Journal of Microscopy © 2015 Royal

  20. 21 CFR 884.6190 - Assisted reproductive microscopes and microscope accessories.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Assisted reproductive microscopes and microscope... Devices § 884.6190 Assisted reproductive microscopes and microscope accessories. (a) Identification. Assisted reproduction microscopes and microscope accessories (excluding microscope stage warmers, which are...

  1. The head-mounted microscope.

    Science.gov (United States)

    Chen, Ting; Dailey, Seth H; Naze, Sawyer A; Jiang, Jack J

    2012-04-01

    Microsurgical equipment has greatly advanced since the inception of the microscope into the operating room. These advancements have allowed for superior surgical precision and better post-operative results. This study focuses on the use of the Leica HM500 head-mounted microscope for the operating phonosurgeon. The head-mounted microscope has an optical zoom from 2× to 9× and provides a working distance from 300 mm to 700 mm. The headpiece, with its articulated eyepieces, adjusts easily to head shape and circumference, and offers a focus function, which is either automatic or manually controlled. We performed five microlaryngoscopic operations utilizing the head-mounted microscope with successful results. By creating a more ergonomically favorable operating posture, a surgeon may be able to obtain greater precision and success in phonomicrosurgery. Phonomicrosurgery requires the precise manipulation of long-handled cantilevered instruments through the narrow bore of a laryngoscope. The head-mounted microscope shortens the working distance compared with a stand microscope, thereby increasing arm stability, which may improve surgical precision. Also, the head-mounted design permits flexibility in head position, enabling operator comfort, and delaying musculoskeletal fatigue. A head-mounted microscope decreases the working distance and provides better ergonomics in laryngoscopic microsurgery. These advances provide the potential to promote precision in phonomicrosurgery. Copyright © 2011 The American Laryngological, Rhinological, and Otological Society, Inc.

  2. Quantitative Imaging with a Mobile Phone Microscope

    Science.gov (United States)

    Skandarajah, Arunan; Reber, Clay D.; Switz, Neil A.; Fletcher, Daniel A.

    2014-01-01

    Use of optical imaging for medical and scientific applications requires accurate quantification of features such as object size, color, and brightness. High pixel density cameras available on modern mobile phones have made photography simple and convenient for consumer applications; however, the camera hardware and software that enables this simplicity can present a barrier to accurate quantification of image data. This issue is exacerbated by automated settings, proprietary image processing algorithms, rapid phone evolution, and the diversity of manufacturers. If mobile phone cameras are to live up to their potential to increase access to healthcare in low-resource settings, limitations of mobile phone–based imaging must be fully understood and addressed with procedures that minimize their effects on image quantification. Here we focus on microscopic optical imaging using a custom mobile phone microscope that is compatible with phones from multiple manufacturers. We demonstrate that quantitative microscopy with micron-scale spatial resolution can be carried out with multiple phones and that image linearity, distortion, and color can be corrected as needed. Using all versions of the iPhone and a selection of Android phones released between 2007 and 2012, we show that phones with greater than 5 MP are capable of nearly diffraction-limited resolution over a broad range of magnifications, including those relevant for single cell imaging. We find that automatic focus, exposure, and color gain standard on mobile phones can degrade image resolution and reduce accuracy of color capture if uncorrected, and we devise procedures to avoid these barriers to quantitative imaging. By accommodating the differences between mobile phone cameras and the scientific cameras, mobile phone microscopes can be reliably used to increase access to quantitative imaging for a variety of medical and scientific applications. PMID:24824072

  3. Quantitative imaging with a mobile phone microscope.

    Directory of Open Access Journals (Sweden)

    Arunan Skandarajah

    Full Text Available Use of optical imaging for medical and scientific applications requires accurate quantification of features such as object size, color, and brightness. High pixel density cameras available on modern mobile phones have made photography simple and convenient for consumer applications; however, the camera hardware and software that enables this simplicity can present a barrier to accurate quantification of image data. This issue is exacerbated by automated settings, proprietary image processing algorithms, rapid phone evolution, and the diversity of manufacturers. If mobile phone cameras are to live up to their potential to increase access to healthcare in low-resource settings, limitations of mobile phone-based imaging must be fully understood and addressed with procedures that minimize their effects on image quantification. Here we focus on microscopic optical imaging using a custom mobile phone microscope that is compatible with phones from multiple manufacturers. We demonstrate that quantitative microscopy with micron-scale spatial resolution can be carried out with multiple phones and that image linearity, distortion, and color can be corrected as needed. Using all versions of the iPhone and a selection of Android phones released between 2007 and 2012, we show that phones with greater than 5 MP are capable of nearly diffraction-limited resolution over a broad range of magnifications, including those relevant for single cell imaging. We find that automatic focus, exposure, and color gain standard on mobile phones can degrade image resolution and reduce accuracy of color capture if uncorrected, and we devise procedures to avoid these barriers to quantitative imaging. By accommodating the differences between mobile phone cameras and the scientific cameras, mobile phone microscopes can be reliably used to increase access to quantitative imaging for a variety of medical and scientific applications.

  4. Commentary: Giuseppe Campani (1635-1715, Rome, Italy): the First Use of a Microscope in Medicine and Surgery.

    Science.gov (United States)

    Brogna, Christian; Millesi, Matthias; Fiengo, Leslie; Richardson, Mark; Bhangoo, Ranjeev; Ashkan, Keyoumars; Türe, Ugur

    2018-02-01

    Giuseppe Campani (1635-1715) was a polymath in Rome, Italy, during the Scientific Revolution in the XVIIth century. In particular, he forged the screw barrel microscope and was manufacturing his own lenses for microscopes and telescopes. He mastered the art of lens grinding. Those lenses have been analyzed with modern methods and turned out to be of extremely good quality, shining light on the fact that Giuseppe Campani mastered the theories of optics. Moreover, in a letter that Giuseppe Campani sent to Pope Innocent XI, he clearly described the use of a microscope for the examination of wounds of legs. This letter dates back to 15 August 1686 and is the first evidence of the use of microscopes to analyze wounds, sores, and anatomic specimens in medical and surgical settings. MG Yasargil previously showed the lithography accompanying this letter and was the first to recognize its great importance. We accessed this original letter in the Vatican Library, and for the first time we have translated it from Latin to English in order to unveil its significance in the context of the Scientific Revolution and the history of medicine and surgery. Copyright © 2017 by the Congress of Neurological Surgeons.

  5. Atomic force microscope with integrated optical microscope for biological applications

    OpenAIRE

    Putman, Constant A.J.; Putman, C.A.J.; van der Werf, Kees; de Grooth, B.G.; van Hulst, N.F.; Segerink, Franciscus B.; Greve, Jan

    1992-01-01

    Since atomic force microscopy (AFM) is capable of imaging nonconducting surfaces, the technique holds great promises for high‐resolution imaging of biological specimens. A disadvantage of most AFMs is the fact that the relatively large sample surface has to be scanned multiple times to pinpoint a specific biological object of interest. Here an AFM is presented which has an incorporated inverted optical microscope. The optical image from the optical microscope is not obscured by the cantilever...

  6. Tracking nanoparticles in an optical microscope using caustics

    International Nuclear Information System (INIS)

    Patterson, Eann A; Whelan, Maurice P

    2008-01-01

    An elegant method is proposed and demonstrated for tracking the location and movement of nanoparticles in an optical microscope using the optical phenomenon of caustics. A simple and reversible adjustment to the microscope generates caustics several orders of magnitude larger than the particles. The method offers a simple and relatively inexpensive method for visualizing such phenomena as the formation of self-assembled monolayers and the interaction of nanoparticles with chemically functionalized surfaces

  7. Tracking nanoparticles in an optical microscope using caustics

    Energy Technology Data Exchange (ETDEWEB)

    Patterson, Eann A [Department of Mechanical Engineering, Michigan State University, East Lansing, MI 48824 (United States); Whelan, Maurice P [Nanotechnology and Molecular Imaging Unit, Institute for Health and Consumer Protection, European Commission DG Joint Research Center, 21021 Ispra (Vatican City State, Holy See,) (Italy)

    2008-03-12

    An elegant method is proposed and demonstrated for tracking the location and movement of nanoparticles in an optical microscope using the optical phenomenon of caustics. A simple and reversible adjustment to the microscope generates caustics several orders of magnitude larger than the particles. The method offers a simple and relatively inexpensive method for visualizing such phenomena as the formation of self-assembled monolayers and the interaction of nanoparticles with chemically functionalized surfaces.

  8. Mobile microscope complex GIB-1

    International Nuclear Information System (INIS)

    Belyakov, A.V.; Gorbachev, A.N.

    2002-01-01

    To study microstructure in operating pipelines of power units a mobile microscope system is developed and successfully used. The system includes a portable microscope, a monitor, power supply and a portable computer. The monitor is used for surveying images from a video camera mounted on the microscope. The magnification on visual examination constitutes x 100 and x 500. Diameters of pipelines examined should not be less than 130 mm. Surface preparation for microstructural studies includes routine mechanical rough grinding and polishing with subsequent etching [ru

  9. The deuteron microscopic optical potential

    International Nuclear Information System (INIS)

    Lu Congshan; Zhang Jingshang; Shen Qingbiao

    1991-01-01

    The two particle Green's function is introduced. When the direct interaction between two nucleons is neglected, the first and second order mass operators of two particles are the sum of those for each particle. The nucleon microscopic optical potential is calculated by applying nuclear matter approximation and effective Skyrme interaction. Then the deuteron microscopic optical potential (DMOP) is calculated by using fold formula. For improvement of the theory, the two particle polarization diagram contribution to the imaginary part of the deuteron microscopic optical potential is studied

  10. Microscopic Procedures for Plant Meiosis.

    Science.gov (United States)

    Braselton, James P.

    1997-01-01

    Describes laboratory techniques designed to familiarize students with meiosis and how microscopic preparations of meiosis are made. These techniques require the use of fresh or fixed flowers. Contains 18 references. (DDR)

  11. A fluorescence scanning electron microscope

    International Nuclear Information System (INIS)

    Kanemaru, Takaaki; Hirata, Kazuho; Takasu, Shin-ichi; Isobe, Shin-ichiro; Mizuki, Keiji; Mataka, Shuntaro; Nakamura, Kei-ichiro

    2009-01-01

    Fluorescence techniques are widely used in biological research to examine molecular localization, while electron microscopy can provide unique ultrastructural information. To date, correlative images from both fluorescence and electron microscopy have been obtained separately using two different instruments, i.e. a fluorescence microscope (FM) and an electron microscope (EM). In the current study, a scanning electron microscope (SEM) (JEOL JXA8600 M) was combined with a fluorescence digital camera microscope unit and this hybrid instrument was named a fluorescence SEM (FL-SEM). In the labeling of FL-SEM samples, both Fluolid, which is an organic EL dye, and Alexa Fluor, were employed. We successfully demonstrated that the FL-SEM is a simple and practical tool for correlative fluorescence and electron microscopy.

  12. Modern Organization of Entrepreneurial Business

    OpenAIRE

    Liudmila Rosca-Sadurschi

    2013-01-01

    This article gives the notion of "entrepreneurial business" and is compared to "business inovations". It analyzes the advantages of these two notions. Modern methods are presented and analyzed to develop an innovative business through reengineering, incubators, business centers, clusters and others. It is also considered the experience of the Danube in practicing these organizational arrangements to develop business.

  13. Quantitative detection of microscopic lithium distributions with neutrons

    Energy Technology Data Exchange (ETDEWEB)

    Neri, Giulia; Gernhaeuser, Roman; Lichtinger, Josef; Winkler, Sonja; Seiler, Dominik; Bendel, Michael [Technische Universitaet Muenchen, Physik-Department (Germany); Kunze-Liebhaeuser, Julia; Brumbarov, Jassen; Portenkirchner, Engelbert [Institut fuer Physikalische Chemie, Leopold-Franzens-Universitaet Innsbruck (Austria); Renno, Axel; Rugel, Georg [Helmholtz Zentrum Dresden Rossendorf, Helmholtz-Institut Freiberg fuer Ressourcentechnologie (Germany)

    2016-07-01

    The importance of lithium in the modern industrial society is continuously increasing. Spatially resolved detection of tritium particles from {sup 6}Li(n,α){sup 3}H nuclear reactions is used to reconstruct microscopic lithium distributions. Samples are exposed to a flux of cold neutrons. Emitted charged particles are detected with a PSD. Introducing a pinhole aperture between target and detector, the experimental setup works like a ''camera obscura'', allowing to perform spatially resolved measurements. Tritium detection analysis was successfully used to reconstruct the lithium content in self-organized TiO{sub 2-x}-C and Si/TiO{sub 2-x}-C nanotubes electrochemically lithiated, for the first time. Titanium dioxide nanotubes are a candidate for a safe anode material in lithium-ion batteries. Also lithium distributions in geological samples, so called ''pathfinder-minerals'' containing lithium, like lepidolite from a pegmatite, were analyzed. With this development we present a new precision method using nuclear physics for material science.

  14. Microscopic modelling of doped manganites

    International Nuclear Information System (INIS)

    Weisse, Alexander; Fehske, Holger

    2004-01-01

    Colossal magneto-resistance manganites are characterized by a complex interplay of charge, spin, orbital and lattice degrees of freedom. Formulating microscopic models for these compounds aims at meeting two conflicting objectives: sufficient simplification without excessive restrictions on the phase space. We give a detailed introduction to the electronic structure of manganites and derive a microscopic model for their low-energy physics. Focusing on short-range electron-lattice and spin-orbital correlations we supplement the modelling with numerical simulations

  15. On thermodynamic and microscopic reversibility

    International Nuclear Information System (INIS)

    Crooks, Gavin E

    2011-01-01

    The word 'reversible' has two (apparently) distinct applications in statistical thermodynamics. A thermodynamically reversible process indicates an experimental protocol for which the entropy change is zero, whereas the principle of microscopic reversibility asserts that the probability of any trajectory of a system through phase space equals that of the time reversed trajectory. However, these two terms are actually synonymous: a thermodynamically reversible process is microscopically reversible, and vice versa

  16. Microscopic theory of particle-vibration coupling

    Energy Technology Data Exchange (ETDEWEB)

    Colo, Gianluca; Bortignon, Pier Francesco [Dipartimento di Fisica, Universita degli Studi di Milano and INFN, Sez. di Milano, via Celoria 16, 20133 Milano (Italy); Sagawa, Hiroyuki [Center for Mathematics and Physics, University of Aizu, Aizu-Wakamatsu, Fukushima 965-8560 (Japan); Moghrabi, Kassem; Grasso, Marcella; Giai, Nguyen Van, E-mail: colo@mi.infn.it [Institut de Physique Nucleaire, Universite Paris-Sud, IN2P3-CNRS, 91406 Orsay Cedex (France)

    2011-09-16

    Some recent microscopic implementations of the particle-vibration coupling (PVC) theory for atomic nuclei are briefly reviewed. Within the nonrelativistic framework, the results seem to point to the necessity of fitting new effective interactions that can work beyond mean field. In keeping with this, the divergences which arise must be cured. A method is proposed, and the future perspectives that are opened are addressed.

  17. Microscopic theory of particle-vibration coupling

    International Nuclear Information System (INIS)

    Colo, Gianluca; Bortignon, Pier Francesco; Sagawa, Hiroyuki; Moghrabi, Kassem; Grasso, Marcella; Giai, Nguyen Van

    2011-01-01

    Some recent microscopic implementations of the particle-vibration coupling (PVC) theory for atomic nuclei are briefly reviewed. Within the nonrelativistic framework, the results seem to point to the necessity of fitting new effective interactions that can work beyond mean field. In keeping with this, the divergences which arise must be cured. A method is proposed, and the future perspectives that are opened are addressed.

  18. The Mathematical Microscope - Making the inaccessible accessible

    DEFF Research Database (Denmark)

    Ottesen, Johnny T.

    2011-01-01

      In this chapter we introduce a new term, the "Mathematical Microscope", as a method of using mathematics in accessing information about reality when this information is otherwise inaccessible. Furthermore, we discuss how models and experiments are related: none of which are important without th...... of mathematical modeling is discussed for type 1 and type 2 diabetes, depression, cardiovascular diseases and the interactions between the combinations of these, the so-called gray triangle in the metabolic syndrome....

  19. Symmetries and microscopic physics

    International Nuclear Information System (INIS)

    Blaizot, J.P.

    1997-01-01

    This book is based on a course of lectures devoted to the applications of group theory to quantum physics. The purpose is to give students a precise idea of general principles involving the concept of symmetry and to present practical methods used to calculate physical properties derived from symmetries. The first chapter is an introduction to the main results of group theory, 2 chapters highlight principles and methods concerning geometrical transformations in the space of states, state degeneracy and perturbation theory. The last 4 chapters investigate the applications of these methods to atom physics, nuclear structure and elementary particles. A chapter is devoted to the atom of hydrogen and another to the isospin. Numerous exercises and problems, some with their corrections, are proposed. (A.C.)

  20. LIBRARIES, SCHOOLS AND MODERN AGE

    Directory of Open Access Journals (Sweden)

    Borjanka Trajković

    2016-04-01

    Full Text Available For centuries the role of the library was defined as a warehouse of books. Now, in the 21st century, the library is facing perhaps the biggest challenge – its physical survival. The role of librarians is re-branded to reflect their expertise as curators of content and reliable navigators in an evergrowing ocean of information - in any format they might exist. The future libraries shall be open to all the new ideas on how to work better and accept the new technologies. On the one hand, they must recognize the need to change their methods, but on the other hand - to preserve the continuity of their objectives and mission. The new era requires modern models of learning and the attractiveness of the curricula, that is, a modern education system that shall adapt the curricula to the needs of modern society and reconcile centuries of man's need for knowledge, reading books and education in general with the new technologies.

  1. Multiplane optical microscope

    Science.gov (United States)

    Li, Tongcang; Ota, Sadao; Kim, Jeongmin; Wang, Yuan; Zhang, Xiang

    2017-11-21

    This disclosure provides systems, methods, and apparatus related to optical microscopy. In one aspect, an apparatus includes a sample holder, a first objective lens, a plurality of optical components, a second objective lens, and a mirror. The apparatus may directly image a cross-section of a sample oblique to or parallel to the optical axis of the first objective lens, without scanning.

  2. [Microscopic investigation of vessel wall after endovascular catheter atherectomy].

    Science.gov (United States)

    Tsygankov, V N; Khovalkin, R G; Chekmareva, I A; Kalinin, D V; Filippova, E M

    2014-01-01

    Endovascular target catheter atherectomy (ETCA) - method of artery patency allowing to obtain occlusion substrate. Given the high destructive effect of atherectome's elements on tissue the objective was determination possibility of histological and electron microscopic investigation of this substrate after atherectomy. The research included 8 patients who underwent ETCA of legs arteries. It was observed substrate removal from broken stent in 1 case. 2 of 8 patients had diabetes. Obtained substrate was available for histological and electron microscopic investigation. Atherosclerosis was confirmed in all cases. It was not observed substrate significant morphological changes in patients with presence or absence of diabetes. Microscopic investigation of substrate from broken stent shows pronounced development of granulation tissue that was regarded as special form of reparative regeneration. Finding internal elastic membrane during microscopic investigation in some cases proves radical intervention. The authors consider that microscopic investigation of substrate after ETCA may be used for diagnosis verification, thorough analysis of morphological changes in lesion area and radicalism of atherectomy.

  3. Er Rousseau moderne?

    DEFF Research Database (Denmark)

    Dupont, Søren

    1985-01-01

    Artiklen analyserer på hvilken måde Rousseau kan siges at være moderne, og den diskuterer på hvilken måde Rouseau har været medvirkende til at opbygge den moderne civilisation, og på hvilken måde han var kritisk i forhold til den gryende og moderne kapitalisme.......Artiklen analyserer på hvilken måde Rousseau kan siges at være moderne, og den diskuterer på hvilken måde Rouseau har været medvirkende til at opbygge den moderne civilisation, og på hvilken måde han var kritisk i forhold til den gryende og moderne kapitalisme....

  4. Late-Modern Symbolism

    DEFF Research Database (Denmark)

    Andersen, Bjørn Schiermer

    2015-01-01

    Through analysis of key texts, I seek to demonstrate the explanative potential of Durkheim’s sociology of religion in the present context. I critically readdress the idea, found in his early work, that modernity is characterized by a rupture with pre-modern forms of solidarity. First, I investigate...... the ways in which Durkheim sets up a stark distinction between the pre-modern and the modern in his early work, and how this distinction is further cemented by his orthodox critique of the modern economy and its negative effects on social life. Second, I show how another timeless and positive understanding...... of “mechanical” solidarity is to be found behind the “symbolist” template crystalizing in Durkheim’s late work. Third, I develop this template for a modern context by critically addressing and removing other obstacles and prejudices on Durkheim’s part....

  5. Indonesia - Procurement Modernization

    Data.gov (United States)

    Millennium Challenge Corporation — The evaluation seeks to establish evidence on the possible effects of an intervention designed to modernize public procurement: effects on cost savings, performance...

  6. Annals of Modern Education

    African Journals Online (AJOL)

    The Annals of Modern Education will be considered for publication publishes regular papers reporting ... Curriculum and Teaching, Students' Perspectives on Learning Environments, Environmental Education, ... AJOL African Journals Online.

  7. Nuclear weapons modernizations

    Energy Technology Data Exchange (ETDEWEB)

    Kristensen, Hans M. [Federation of American Scientists, Washington, DC (United States)

    2014-05-09

    This article reviews the nuclear weapons modernization programs underway in the world's nine nuclear weapons states. It concludes that despite significant reductions in overall weapons inventories since the end of the Cold War, the pace of reductions is slowing - four of the nuclear weapons states are even increasing their arsenals, and all the nuclear weapons states are busy modernizing their remaining arsenals in what appears to be a dynamic and counterproductive nuclear competition. The author questions whether perpetual modernization combined with no specific plan for the elimination of nuclear weapons is consistent with the nuclear Non-Proliferation Treaty and concludes that new limits on nuclear modernizations are needed.

  8. Microscopic model for the non-linear fluctuating hydrodynamic of {sup 4} He superfluid helium deduced by maximum entropy method; Modelo microscopico para la hidrodinamica fluctuante no lineal del {sup 4}He superfluido deducido mediante el metodo de maxima entropia

    Energy Technology Data Exchange (ETDEWEB)

    Alvarez R, J.T

    1998-10-01

    This thesis presents a microscopic model for the non-linear fluctuating hydrodynamic of superfluid helium ({sup 4} He), model developed by means of the Maximum Entropy Method (Maxent). In the chapter 1, it is demonstrated the necessity to developing a microscopic model for the fluctuating hydrodynamic of the superfluid helium, starting from to show a brief overview of the theories and experiments developed in order to explain the behavior of the superfluid helium. On the other hand, it is presented the Morozov heuristic method for the construction of the non-linear hydrodynamic fluctuating of simple fluid. Method that will be generalized for the construction of the non-linear fluctuating hydrodynamic of the superfluid helium. Besides, it is presented a brief summary of the content of the thesis. In the chapter 2, it is reproduced the construction of a Generalized Fokker-Planck equation, (GFP), for a distribution function associated with the coarse grained variables. Function defined with aid of a nonequilibrium statistical operator {rho}hut{sub FP} that is evaluated as Wigneris function through {rho}{sub CG} obtained by Maxent. Later this equation of GFP is reduced to a non-linear local FP equation from considering a slow and Markov process in the coarse grained variables. In this equation appears a matrix D{sub mn} defined with a nonequilibrium coarse grained statistical operator {rho}hut{sub CG}, matrix elements are used in the construction of the non-linear fluctuating hydrodynamics equations of the superfluid helium. In the chapter 3, the Lagrange multipliers are evaluated for to determine {rho}hut{sub CG} by means of the local equilibrium statistical operator {rho}hut{sub l}-tilde with the hypothesis that the system presents small fluctuations. Also are determined the currents associated with the coarse grained variables and furthermore are evaluated the matrix elements D{sub mn} but with aid of a quasi equilibrium statistical operator {rho}hut{sub qe} instead

  9. Axiomatic electrodynamics and microscopic mechanics

    International Nuclear Information System (INIS)

    Yussouff, M.

    1981-04-01

    A new approach to theoretical physics, along with the basic formulation of a new MICROSCOPIC MECHANICS for the motion of small charged particles is described in this set of lecture notes. Starting with the classical (Newtonian) mechanics and classical fields, the important but well known properties of Classical Electromagnetic field are discussed up to section 4. The next nection describes the usual radiation damping theory and its difficulties. It is argued that the usual treatment of radiation damping is not valid for small space and time intervals and the true description of motion requires a new type of mechanics - the MICROSCOPIC MECHANICS: Section 6 and 7 are devoted to showing that not only the new microscopic mechanics goes over to Newtonian mechanics in the proper limit, but also it is closely connected with Quantum Mechanics. All the known results of the Schroedinger theory can be reproduced by microscopic mechanics which also gives a clear physical picture. It removes Einstein's famous objections against Quantum Theory and provides a clear distinction between classical and Quantum behavior. Seven Axioms (three on Classical Mechanics, two for Maxwell's theory, one for Relativity and a new Axiom on Radiation damping) are shown to combine Classical Mechanics, Maxwellian Electrodynamics, Relativity and Schroedinger's Quantum Theory within a single theoretical framework under Microscopic Mechanics which awaits further development at the present time. (orig.)

  10. Portable smartphone based quantitative phase microscope

    Science.gov (United States)

    Meng, Xin; Tian, Xiaolin; Yu, Wei; Kong, Yan; Jiang, Zhilong; Liu, Fei; Xue, Liang; Liu, Cheng; Wang, Shouyu

    2018-01-01

    To realize portable device with high contrast imaging capability, we designed a quantitative phase microscope using transport of intensity equation method based on a smartphone. The whole system employs an objective and an eyepiece as imaging system and a cost-effective LED as illumination source. A 3-D printed cradle is used to align these components. Images of different focal planes are captured by manual focusing, followed by calculation of sample phase via a self-developed Android application. To validate its accuracy, we first tested the device by measuring a random phase plate with known phases, and then red blood cell smear, Pap smear, broad bean epidermis sections and monocot root were also measured to show its performance. Owing to its advantages as accuracy, high-contrast, cost-effective and portability, the portable smartphone based quantitative phase microscope is a promising tool which can be future adopted in remote healthcare and medical diagnosis.

  11. Electron microscopic radioautography of the cell

    International Nuclear Information System (INIS)

    Sarkisov, D.S.; Pal'tsyn, A.A.; Vtyurin, B.V.

    1980-01-01

    This monograph is the first one in the world literature that gives th generalised experience in application of the up-to-date method of structural and functional analysis, i.e. of electron-microscopic autography to study the dynamics of intracellular processes under normal conditions as well as under some pathogenic effects. Given herein are the data on synthesis of DNA and RNA in various structures of the nucleus, particularly in nucleoli, the regularities of the synthesis processes in the organellae of the same name are discussed; illustrated are the possibilities of structure analysis of biosynthesis intensity variations in the nucleus and cytoplasma in cells of liver miocardium, granulation tissue at different stages of morphological process; the results of electron-microscopic radioautography application in study of clinical biopsy material are given and the data obtained are discussed in the light of general pathology problems

  12. Isotope analysis in the transmission electron microscope.

    Science.gov (United States)

    Susi, Toma; Hofer, Christoph; Argentero, Giacomo; Leuthner, Gregor T; Pennycook, Timothy J; Mangler, Clemens; Meyer, Jannik C; Kotakoski, Jani

    2016-10-10

    The Ångström-sized probe of the scanning transmission electron microscope can visualize and collect spectra from single atoms. This can unambiguously resolve the chemical structure of materials, but not their isotopic composition. Here we differentiate between two isotopes of the same element by quantifying how likely the energetic imaging electrons are to eject atoms. First, we measure the displacement probability in graphene grown from either 12 C or 13 C and describe the process using a quantum mechanical model of lattice vibrations coupled with density functional theory simulations. We then test our spatial resolution in a mixed sample by ejecting individual atoms from nanoscale areas spanning an interface region that is far from atomically sharp, mapping the isotope concentration with a precision better than 20%. Although we use a scanning instrument, our method may be applicable to any atomic resolution transmission electron microscope and to other low-dimensional materials.

  13. Response function and optimum configuration of semiconductor backscattered-electron detectors for scanning electron microscopes

    International Nuclear Information System (INIS)

    Rau, E. I.; Orlikovskiy, N. A.; Ivanova, E. S.

    2012-01-01

    A new highly efficient design for semiconductor detectors of intermediate-energy electrons (1–50 keV) for application in scanning electron microscopes is proposed. Calculations of the response function of advanced detectors and control experiments show that the efficiency of the developed devices increases on average twofold, which is a significant positive factor in the operation of modern electron microscopes in the mode of low currents and at low primary electron energies.

  14. Optical microscope for three-dimensional surface displacement and shape measurements at the microscale.

    Science.gov (United States)

    Xia, Shuman; Pan, Zhipeng; Zhang, Jingwen

    2014-07-15

    We report a novel optical microscope for full-field, noncontact measurements of three-dimensional (3D) surface deformation and topography at the microscale. The microscope system is based on a seamless integration of the diffraction-assisted image correlation (DAIC) method with fluorescent microscopy. We experimentally demonstrate the microscope's capability for 3D measurements with submicrometer spatial resolution and subpixel measurement accuracy.

  15. Modern examples of extinctions

    DEFF Research Database (Denmark)

    Lövei, Gabor L

    2013-01-01

    No species lives forever, and extinction is the ultimate fate of all living species. The fossil record indicates that a recent extinction wave affecting terrestrial vertebrates was parallel with the arrival of modern humans to areas formerly uninhabited by them. These modern instances of extinction...

  16. Modern History of Tibet

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    Authored by Xu Guangzhi, this book is a subsidiary project of Research Into Traditional Culture and History (of the PRC Ministry of Education) conducted by China Tibetology Research Institute of Tibet University. The book combines modern history of Tibet with modern history of China as a whole. It tells the close ties between various members of the Chinese nation.

  17. Adult learning in modernity

    DEFF Research Database (Denmark)

    Rasmussen, Palle

    2007-01-01

    The paper discusses the conditions for the growth of adult education in modern societies. It is argued that in modern adult life individual biographical reflection plays an increasing role, not only for educational and occupational choice but also in the process of identity formation and emotional...

  18. Liquid Modernity & Late Capitalism

    DEFF Research Database (Denmark)

    Hansen, Claus D.

    In Liquid Modernity, Bauman portrays Adorno and the rest of the early Frankfurt School as sociologists and thinkers belonging to the ‘heavy’ phase of modernity. In other words, they are deemed irrelevant to the discussion of current sociological time diagnoses and the purpose of critique under co...

  19. Understanding modern transparency

    NARCIS (Netherlands)

    Meijer, A.J.|info:eu-repo/dai/nl/172436729

    2009-01-01

    Proponents and opponents fiercely debate whether computer-mediated transparency has a positive effect on trust in the public sector. This article enhances our understanding of transparency by presenting three perspectives: a premodern, modern and post-modern perspective, and analyzing the basic

  20. Early Modern Philosophical Systems

    NARCIS (Netherlands)

    L. van Bunge (Wiep)

    2014-01-01

    textabstractThe occurrence of an entry on early modern philosophical systems in an encyclopaedia of Neo-Latin studies is fraught with complications, if only on account of the gradual disappearance during the early modern period of Latin as the main vehicle of philosophical communication. What