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Sample records for models good agreement

  1. MEDIATION AGREEMENTS LEGAL MODEL

    Directory of Open Access Journals (Sweden)

    Alexander Ponomarev

    2015-07-01

    Full Text Available This article focuses on the legal model of mediation agreements in Russian and international legislation. The authors consider the main provisions of the mediation agreements in civil matters, in particular, is defined by such features of the legal model as the requirements for this type of agreements. In addition, the article discusses the problematic issues of implementation of mediation agreements.

  2. How good is good in hydrological modeling?

    Science.gov (United States)

    Seibert, J.; Vis, M.; van Meerveld, I. H. J.

    2016-12-01

    Models are never perfect and hydrological models are no exception. Even with the most sophisticated hydrological models, runoff simulations never fully agree. This is at least partly because of uncertainties in the observed input and output data. On the other hand, even a poor model can often provide fair simulations simply because the forcing data (precipitation, temperature, …) do not allow the model to go completely wrong. Commonly used measures to assess model performance, such as the Nash-Sutcliffe model efficiency, do not allow direct judgment of model performance in terms of what can be achieved with a certain dataset, and different guidelines are given in the literature on what values indicate a good model performance. This is not satisfactory, especially when it comes to assessing the performances of uncalibrated models. We, therefore, suggest the use of an upper and a lower benchmark to better assess model performance. The upper benchmark is a measure of what can be achieved and can be quantified by the performance of a calibrated simple model. The lower benchmark is a measure of what can be expected and can be quantified by an ensemble mean of an uncalibrated simple model where random parameter sets or parameter sets from other catchments are used. In this contribution, we focus on this lower benchmark. Preliminary results using the HBV model, a simple, bucket-type model, indicated surprisingly good model performance of the ensemble means, even when individual parameterisations resulted in very poor fits. To test this further, we applied the HBV model using data from 600 catchments in the USA. The model was calibrated for each catchment and different ensembles where used to compute ensemble mean time series based on: 1) random parameter values, 2) parameter sets from all 600 catchments (minus the one in question), 3) parameter sets from all catchments in the respective hydrological region as defined by the USGS, and 4) parameter sets from the x nearest

  3. Modeling agreement on bounded scales.

    Science.gov (United States)

    Vanbelle, Sophie; Lesaffre, Emmanuel

    2017-01-01

    Agreement is an important concept in medical and behavioral sciences, in particular in clinical decision making where disagreements possibly imply a different patient management. The concordance correlation coefficient is an appropriate measure to quantify agreement between two scorers on a quantitative scale. However, this measure is based on the first two moments, which could poorly summarize the shape of the score distribution on bounded scales. Bounded outcome scores are common in medical and behavioral sciences. Typical examples are scores obtained on visual analog scales and scores derived as the number of positive items on a questionnaire. These kinds of scores often show a non-standard distribution, like a J- or U-shape, questioning the usefulness of the concordance correlation coefficient as agreement measure. The logit-normal distribution has shown to be successful in modeling bounded outcome scores of two types: (1) when the bounded score is a coarsened version of a latent score with a logit-normal distribution on the [0,1] interval and (2) when the bounded score is a proportion with the true probability having a logit-normal distribution. In the present work, a model-based approach, based on a bivariate generalization of the logit-normal distribution, is developed in a Bayesian framework to assess the agreement on bounded scales. This method permits to directly study the impact of predictors on the concordance correlation coefficient and can be simply implemented in standard Bayesian softwares, like JAGS and WinBUGS. The performances of the new method are compared to the classical approach using simulations. Finally, the methodology is used in two different medical domains: cardiology and rheumatology.

  4. Goods Transport Modelling, Vol 1

    DEFF Research Database (Denmark)

    Petersen, Morten Steen (red.); Kristiansen, Jørgen

    The report is a study of data requirements and methodologies for goods transport. The study is intended to provide the basis for general discussion about the application of goods transport models in Denmark. The report provides an overview of different types of models and data availability....

  5. Client/consultant model services agreement

    CERN Document Server

    International Federation of Consulting Engineers

    2006-01-01

    The terms of the Client Consultant Model Services agreement (The White Book) have been prepared by the Fédération Internationale des Ingénieurs-Conseils (FIDIC) and are recommended for general use for the purposes of pre-investment and feasibility studies, designs and administration of construction and project management, where proposals for such services are invited on an international basis. They are equally adaptable for domestic agreements. - See more at: http://fidic.org/books/clientconsultant-model-services-agreement-4th-ed-2006-white-book#sthash.3Uxy5qT3.dpuf

  6. Sticky Price Models and Durable Goods

    OpenAIRE

    Robert Barsky; Christopher L. House; Miles Kimball

    2005-01-01

    This paper shows that there are striking implications that stem from including durable goods in otherwise conventional sticky price models. The behavior of these models depends heavily on whether durable goods are present and whether these goods have sticky prices. If long-lived durables have sticky prices, then even small durables sectors can cause the model to behave as though most prices were sticky. Conversely, if durable goods prices are flexible then the model exhibits unwelcome behavio...

  7. DELIVERY OF GOOD IN THE LOAN AGREEMENT: CONDITION OF VALIDITY OR OBLIGATION OF THE LENDER?

    Directory of Open Access Journals (Sweden)

    LIVIU STANCIULESCU

    2011-04-01

    Full Text Available In theory, the loan is generally defined as a contract whereby a person, called the lender, shall use or immovable property of another person, called the loan, which is obliged to repay in kind. Based on the definition above national doctrine is unanimous in determining that the loan is a unilateral contract, because creates obligations only for the borrower. Similarly, the loan is a real contract because the manifestation of will must be accompanied by delivery of the good. Given the above, the question is obvious: delivery of the borrowed good is a condition of validity of the contract (specific for its formation or an obligation of the borrower (operating in the execution phase ? Please note that determining the legal nature of the good delivery has great importance to the doctrine and practice. Thus, relative to the approach adopted: „delivery - a condition of validity” or „ delivery - obligation of the lender”, legal consequences are totally different, with direct implications in defining the actual contract, the contract unilaterally rescinded the conditions in which they operate, etc.. In our approach we try to demonstrate that good delivery in the loan agreement can only be an obligation of the borrower (with all consequences arising from such qualification.

  8. Development and implementation of the Good Neighbor Agreement (GNA) practice in the USA sustainable mining development.

    Science.gov (United States)

    Masaitis, Alexandra

    2014-05-01

    New economic, environmental and social challenges for the mining industry in the USA show the need to implement "responsible" mining practices that include improved community involvement. Conflicts which occur in the US territory and with US mining companies around the world are now common between the mining proponents, NGO's and communities. These conflicts can sometimes be alleviated by early development of modes of communication, and a formal discussion format that allows airing of concerns and potential resolution of problems. One of the methods that can formalize this process is to establish a Good Neighbor Agreement (GNA), which deals specifically with challenges in relationships between mining operations and the local communities. It is a new practice related to mining operations that are oriented toward social needs and concerns of local communities that arise during the normal life of a mine, which can achieve sustainable mining practices. The GNA project being currently developed at the University of Nevada, USA in cooperation with the Newmont Mining Corporation has a goal of creating an open company/community dialog that will help identify and address sociological and environmental concerns associated with mining. Discussion: The Good Neighbor Agreement currently evolving will address the following: 1. Identify spheres of possible cooperation between mining companies, government organizations, and NGO's. 2. Provide an economically viable mechanism for developing a partnership between mining operations and the local communities that will increase mining industry's accountability and provide higher levels of confidence for the community that a mine is operated in a safe and sustainable manner. Implementation of the GNA can help identify and evaluate conflict criteria in mining/community relationships; determine the status of concerns; determine the role and responsibilities of stakeholders; analyze problem resolution feasibility; maintain the community

  9. Good interobserver agreement was attainable on outcome adjudication in patients with stable coronary heart disease

    DEFF Research Database (Denmark)

    Kjoller, Erik; Hilden, Jorgen; Winkel, Per;

    2012-01-01

    OBJECTIVE: In clinical trials, agreement on outcomes is of utmost importance for valid estimation of intervention effects. As there is limited knowledge about adjudicator agreement in cardiology, we examined the level of agreement among three cardiology specialists adjudicating all possible event...

  10. Features of the Maintenance Agreement (Contract for the Delivery of Goods, Works and Services for State and Municipal Needs

    Directory of Open Access Journals (Sweden)

    Evgeniya V. Loginova

    2015-12-01

    Full Text Available Article analyzes main features of the agreement (contract for the delivery of goods, works and services for state and municipal needs. It is shown that civil-legal nature of this agreement, which aims to meet the public interest. It is emphasized that this agreement is the special subject composition. Features of this type of contract, which is manifested in the use of special methods of placing state and municipal orders are shown. It is proved that for the public contract subject of the contract will depend on the considered whether the supply agreement or service contract. Existing in the modern civil law doctrine approaches to understanding the essential terms of the contract are analyzed. Features of pricing in this agreement is shown. It was concluded that, in contrast to other types of civil contracts, state contract has a wide range of essential conditions.

  11. Features of the Maintenance Agreement (Contract) for the Delivery of Goods, Works and Services for State and Municipal Needs

    OpenAIRE

    Evgeniya V. Loginova

    2015-01-01

    Article analyzes main features of the agreement (contract) for the delivery of goods, works and services for state and municipal needs. It is shown that civil-legal nature of this agreement, which aims to meet the public interest. It is emphasized that this agreement is the special subject composition. Features of this type of contract, which is manifested in the use of special methods of placing state and municipal orders are shown. It is proved that for the public contract subject of the co...

  12. Conceptual Models Core to Good Design

    CERN Document Server

    Johnson, Jeff

    2011-01-01

    People make use of software applications in their activities, applying them as tools in carrying out tasks. That this use should be good for people--easy, effective, efficient, and enjoyable--is a principal goal of design. In this book, we present the notion of Conceptual Models, and argue that Conceptual Models are core to achieving good design. From years of helping companies create software applications, we have come to believe that building applications without Conceptual Models is just asking for designs that will be confusing and difficult to learn, remember, and use. We show how Concept

  13. Good things come to those who wait: late first offers facilitate creative agreements in negotiation.

    Science.gov (United States)

    Sinaceur, Marwan; Maddux, William W; Vasiljevic, Dimitri; Perez Nückel, Ricardo; Galinsky, Adam D

    2013-06-01

    Although previous research has shown that making the first offer leads to a distributive advantage in negotiations, the current research explored how the timing of first offers affects the creativity of negotiation agreements. We hypothesized that making the first offer later rather than earlier in the negotiation would facilitate the discovery of creative agreements that better meet the parties' underlying interests. Experiment 1 demonstrated that compared with early first offers, late first offers facilitated creative agreements that better met the parties' underlying interests. Experiments 2a and 2b controlled for the duration of the negotiation and conceptually replicated this effect. The last two studies also demonstrated that the beneficial effect of late first offers was mediated by greater information exchange. Thus, negotiators need to consider the timing of first offers to fully capitalize on the first offer advantage. Implications for our understanding of creativity, motivated information exchange, and timing in negotiations are discussed.

  14. Center for Extended Magnetohydrodynamic Modeling Cooperative Agreement

    Energy Technology Data Exchange (ETDEWEB)

    Carl R. Sovinec

    2008-02-15

    The Center for Extended Magnetohydrodynamic Modeling (CEMM) is developing computer simulation models for predicting the behavior of magnetically confined plasmas. Over the first phase of support from the Department of Energy’s Scientific Discovery through Advanced Computing (SciDAC) initiative, the focus has been on macroscopic dynamics that alter the confinement properties of magnetic field configurations. The ultimate objective is to provide computational capabilities to predict plasma behavior—not unlike computational weather prediction—to optimize performance and to increase the reliability of magnetic confinement for fusion energy. Numerical modeling aids theoretical research by solving complicated mathematical models of plasma behavior including strong nonlinear effects and the influences of geometrical shaping of actual experiments. The numerical modeling itself remains an area of active research, due to challenges associated with simulating multiple temporal and spatial scales. The research summarized in this report spans computational and physical topics associated with state of the art simulation of magnetized plasmas. The tasks performed for this grant are categorized according to whether they are primarily computational, algorithmic, or application-oriented in nature. All involve the development and use of the Non-Ideal Magnetohydrodynamics with Rotation, Open Discussion (NIMROD) code, which is described at http://nimrodteam.org. With respect to computation, we have tested and refined methods for solving the large algebraic systems of equations that result from our numerical approximations of the physical model. Collaboration with the Terascale Optimal PDE Solvers (TOPS) SciDAC center led us to the SuperLU_DIST software library [http://crd.lbl.gov/~xiaoye/SuperLU/] for solving large sparse matrices using direct methods on parallel computers. Switching to this solver library boosted NIMROD’s performance by a factor of five in typical large

  15. Global Water Cycle Agreement in the Climate Models Assessed in the IPCC AR4

    Science.gov (United States)

    Waliser, D.; Seo, K. -W.; Schubert, S.; Njoku, E.

    2007-01-01

    This study examines the fidelity of the global water cycle in the climate model simulations assessed in the IPCC Fourth Assessment Report. The results demonstrate good model agreement in quantities that have had a robust global observational basis and that are physically unambiguous. The worst agreement occurs for quantities that have both poor observational constraints and whose model representations can be physically ambiguous. In addition, components involving water vapor (frozen water) typically exhibit the best (worst) agreement, and fluxes typically exhibit better agreement than reservoirs. These results are discussed in relation to the importance of obtaining accurate model representation of the water cycle and its role in climate change. Recommendations are also given for facilitating the needed model improvements.

  16. A note on assessing agreement for frailty models.

    Science.gov (United States)

    Guo, Ying; Manatunga, Amita K

    2010-04-01

    Assessing agreement is often of interest in biomedical sciences to evaluate the similarity of measurements produced by different raters or methods on the same subjects. We investigate the agreement structure for a class of frailty models that are commonly used for analyzing correlated survival outcomes. Conditional on the shared frailty, bivariate survival times are assumed to be independent with Weibull baseline hazard distribution. We present the analytic expressions for the concordance correlation coefficient (CCC) for several commonly used frailty distributions. Furthermore, we develop a time-dependent CCC for measuring agreement between survival times among subjects who survive beyond a specified time point. We characterize the temporal pattern in the time-dependent CCC for various frailty distributions. Our results provide a better understanding of the agreement structure implied by different frailty models.

  17. Good agreements between self and clinician-collected specimens for the detection of human papillomavirus in Brazilian patients

    Directory of Open Access Journals (Sweden)

    Karla Lopes Mandu de Campos

    2014-06-01

    Full Text Available Women infected with human papillomavirus (HPV are at a higher risk of developing cervical lesions. In the current study, self and clinician-collected vaginal and cervical samples from women were processed to detect HPV DNA using polymerase chain reaction (PCR with PGMY09/11 primers. HPV genotypes were determined using type-specific PCR. HPV DNA detection showed good concordance between self and clinician-collected samples (84.6%; kappa = 0.72. HPV infection was found in 30% women and genotyping was more concordant among high-risk HPV (HR-HPV than low-risk HPV (HR-HPV. HPV16 was the most frequently detected among the HR-HPV types. LR-HPV was detected at a higher frequency in self-collected; however, HR-HPV types were more frequently identified in clinician-collected samples than in self-collected samples. HPV infections of multiple types were detected in 20.5% of clinician-collected samples and 15.5% of self-collected samples. In this study, we demonstrated that the HPV DNA detection rate in self-collected samples has good agreement with that of clinician-collected samples. Self-collected sampling, as a primary prevention strategy in countries with few resources, could be effective for identifying cases of HR-HPV, being more acceptable. The use of this method would enhance the coverage of screening programs for cervical cancer.

  18. Magnetic resonance enterography has good inter-rater agreement and diagnostic accuracy for detecting inflammation in pediatric Crohn disease.

    Science.gov (United States)

    Church, Peter C; Greer, Mary-Louise C; Cytter-Kuint, Ruth; Doria, Andrea S; Griffiths, Anne M; Turner, Dan; Walters, Thomas D; Feldman, Brian M

    2017-05-01

    signs and wPCDAI was higher than with CRP. AUC was highest (≥0.75) for ulcers, wall enhancement, wall thickening, wall T2 hyperintensity and wall DWI hyperintensity. Some MRE signs had good inter-rater agreement and AUC for detection of inflammation in children with Crohn disease.

  19. The essential elements and the legal structure of master franchise agreement: How to draft a good contract?

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    Kerković-Milenković Tamara

    2010-01-01

    Full Text Available The creation of the draft and other legal documents in franchising transaction emanates the one of the most stressful challenge for the civil law lawyer. There are many reasons which create big obstacles in process of successfully drafting master franchise agreement. One of the main difficulties faced by the parties engaged in international trade is the lack of uniformed rules for the franchising agreement as well as franchising being anonymous contract in the most of legal systems of the world. Besides that, the franchise (emanating goodwill as the legal object of the franchising agreement is sui generis and fluid derives from the various numbers of rights and licence simmilar to right, such as trade names, trade marks and the shop signs, logos, utility models, designs, copyrights, know-how, etc. The legal structure of the mutual rights and obligations of the parties is extremely sophisticated not only because of the big number of obligations but because of their varieties and complexity. In most of the legal systems of common law as well as in the civil law countries the master franchise contract is not regulated neither with mandatory nor through dispositive norms of relationship laws but at the same time the franchise arrangements are subjected to a considerable number of laws and regulations from different areas of law, majority of which are regulated domestically and at the same time also at international legal context. Those areas of law are general contract law, agency law, leasing and security interests, intelectual property and competiton law, corporate law, insurance and labore law, consumer protection and product liability legislation and always important industry specific laws. In interantional legal practice there are many so-called template franchise agreement which are prepared from the franchisor in advance regulating all possible predictable legal solution and legislation. But, it is advisable for the civil law lawyer to treat

  20. Analysis of Rater Agreement by Rasch and IRT Models

    DEFF Research Database (Denmark)

    Petersen, Jørgen Holm

    2013-01-01

    This chapter first discusses the use of item response theory (IRT) model for the analysis of agreement between raters in a situation where all raters have supplied dichotomous ratings of the same cases in a sample. Next, the chapter describes two approaches to the quantification of the rater...

  1. Demand and routing models for urban goods movement simulation

    OpenAIRE

    Polimeni, Antonio; Russo, Francesco; Vitetta, Antonino

    2010-01-01

    This paper presents a macro-architecture for simulating goods movements in an urban area. Urban goods supply is analysed when the retailer is the decision-maker and chooses to supply his/her shop. Two components are considered: demand in terms of goods supply and vehicle routing with constraints to simulate goods movements. To analyse demand we consider a multi-step model, while to analyse goods movements a Vehicle Routing Problem with Time Windows (VRPTW) is formalized. We exa...

  2. A Good Image Model Eases Restoration

    Science.gov (United States)

    2002-02-06

    algorithms, and various classical as well as unexpected new applications of the BV ( bounded variation ) image model, first introduced into image processing by Rudin, Osher, and Fatemi in 1992 Physica D, 60:259-268.

  3. Recent European Challenges and the Danish Collective Agreement Model

    DEFF Research Database (Denmark)

    Larsen, Trine Pernille; Navrbjerg, Steen Erik

    The Nordic countries collective agreement systems face, similar to other bargaining models, a wide range of challenges as a result of globalisation and increased European integration. Some concern the further development and strengthening of the European and national social dialogue. Others...... are related to the new forms of cross-border collaboration and negotiations taking place within multi-national corporations (MNC's). This research paper examines a series of challenges facing the collective bargaining systems in Denmark, Estonia, Northern Ireland and Sweden. These countries represent four...

  4. Evaluation of Spatial Agreement of Distinct Landslide Prediction Models

    Science.gov (United States)

    Sterlacchini, Simone; Bordogna, Gloria; Frigerio, Ivan

    2013-04-01

    The aim of the study was to assess the degree of spatial agreement of different predicted patterns in a majority of coherent landslide prediction maps with almost similar success and prediction rate curves. If two or more models have a similar performance, the choice of the best one is not a trivial operation and cannot be based on success and prediction rate curves only. In fact, it may happen that two or more prediction maps with similar accuracy and predictive power do not have the same degree of agreement in terms of spatial predicted patterns. The selected study area is the high Valtellina valley, in North of Italy, covering a surface of about 450 km2 where mapping of historical landslides is available. In order to assess landslide susceptibility, we applied the Weights of Evidence (WofE) modeling technique implemented by USGS by means of ARC-SDM tool. WofE efficiently investigate the spatial relationships among past events and multiple predisposing factors, providing useful information to identify the most probable location of future landslide occurrences. We have carried out 13 distinct experiments by changing the number of morphometric and geo-environmental explanatory variables in each experiment with the same training set and thus generating distinct models of landslide prediction, computing probability degrees of occurrence of landslides in each pixel. Expert knowledge and previous results from indirect statistically-based methods suggested slope, land use, and geology the best "driving controlling factors". The Success Rate Curve (SRC) was used to estimate how much the results of each model fit the occurrence of landslides used for the training of the models. The Prediction Rate Curve (PRC) was used to estimate how much the model predict the occurrence of landslides in the validation set. We found that the performances were very similar for different models. Also the dendrogram of the Cohen's kappa statistic and Principal Component Analysis (PCA) were

  5. A general model of the public goods dilemma.

    Science.gov (United States)

    Frank, Steven A

    2010-06-01

    An individually costly act that benefits all group members is a public good. Natural selection favours individual contribution to public good [corrected] only when some benefit to the individual offsets the cost of contribution. Problems of sex ratio, parasite virulence, microbial metabolism, punishment of noncooperators, and nearly all aspects of sociality have been analysed as public goods shaped by kin and group selection. Here, I develop two general aspects of the public goods problem that have received relatively little attention. First, variation in individual resources favours selfish individuals to vary their allocation to public goods. Those individuals better endowed contribute their excess resources to public benefit, whereas those individuals with fewer resources contribute less to the public good. Thus, purely selfish behaviour causes individuals to stratify into upper classes that contribute greatly to public benefit and social cohesion and to lower classes that contribute little to the public good. Second, if group success absolutely requires production of the public good, then the pressure favouring production is relatively high. By contrast, if group success depends weakly on the public good, then the pressure favouring production is relatively weak. Stated in this way, it is obvious that the role of baseline success is important. However, discussions of public goods problems sometimes fail to emphasize this point sufficiently. The models here suggest simple tests for the roles of resource variation and baseline success. Given the widespread importance of public goods, better models and tests would greatly deepen our understanding of many processes in biology and sociality.

  6. Good agreement of conventional and gel-based direct agglutination test in immune-mediated haemolytic anaemia

    Directory of Open Access Journals (Sweden)

    Piek Christine J

    2012-02-01

    Full Text Available Abstract Background The aim of this study was to compare a gel-based test with the traditional direct agglutination test (DAT for the diagnosis of immune-mediated haemolytic anaemia (IMHA. Methods Canine (n = 247 and feline (n = 74 blood samples were submitted for DAT testing to two laboratories. A subset of canine samples was categorized as having idiopathic IMHA, secondary IMHA, or no IMHA. Results The kappa values for agreement between the tests were in one laboratory 0.86 for canine and 0.58 for feline samples, and in the other 0.48 for canine samples. The lower agreement in the second laboratory was caused by a high number of positive canine DATs for which the gel test was negative. This group included significantly more dogs with secondary IMHA. Conclusions The gel test might be used as a screening test for idiopathic IMHA and is less often positive in secondary IMHA than the DAT.

  7. Time series models of environmental exposures: Good predictions or good understanding.

    Science.gov (United States)

    Barnett, Adrian G; Stephen, Dimity; Huang, Cunrui; Wolkewitz, Martin

    2017-04-01

    Time series data are popular in environmental epidemiology as they make use of the natural experiment of how changes in exposure over time might impact on disease. Many published time series papers have used parameter-heavy models that fully explained the second order patterns in disease to give residuals that have no short-term autocorrelation or seasonality. This is often achieved by including predictors of past disease counts (autoregression) or seasonal splines with many degrees of freedom. These approaches give great residuals, but add little to our understanding of cause and effect. We argue that modelling approaches should rely more on good epidemiology and less on statistical tests. This includes thinking about causal pathways, making potential confounders explicit, fitting a limited number of models, and not over-fitting at the cost of under-estimating the true association between exposure and disease. Copyright © 2017 Elsevier Inc. All rights reserved.

  8. Model of wealth and goods dynamics in a closed market

    Science.gov (United States)

    Ausloos, Marcel; Peķalski, Andrzej

    2007-01-01

    A simple computer simulation model of a closed market on a fixed network with free flow of goods and money is introduced. The model contains only two variables: the amount of goods and money beside the size of the system. An initially flat distribution of both variables is presupposed. We show that under completely random rules, i.e. through the choice of interacting agent pairs on the network and of the exchange rules that the market stabilizes in time and shows diversification of money and goods. We also indicate that the difference between poor and rich agents increases for small markets, as well as for systems in which money is steadily deduced from the market through taxation. It is also found that the price of goods decreases when taxes are introduced, likely due to the less availability of money.

  9. Good agreement between questionnaire and administrative databases for health care use and costs in patients with osteoarthritis

    Directory of Open Access Journals (Sweden)

    Robertson M Clare

    2011-04-01

    Full Text Available Abstract Background Estimating costs is essential to the economic analysis of health care programs. Health care costs are often captured from administrative databases or by patient report. Administrative records only provide a partial representation of health care costs and have additional limitations. Patient-completed questionnaires may allow a broader representation of health care costs; however the validity and feasibility of such methods have not been firmly established. This study was conducted to assess the validity and feasibility of using a patient-completed questionnaire to capture health care use and costs for patients with osteoarthritis, and to compare the research costs of the data-capture methods. Methods We designed a patient questionnaire and applied it in a clinical trial. We captured equivalent data from four administrative databases. We evaluated aspects of the questionnaire's validity using sensitivity and specificity, Lin's concordance correlation coefficient (ρc, and Bland-Altman comparisons. Results The questionnaire's response rate was 89%. Acceptable sensitivity and specificity levels were found for all types of health care use. The numbers of visits and the majority of medications reported by patients were in agreement with the database-derived estimates (ρc > 0.40. Total cost estimates from the questionnaire agreed with those from the databases. Patient-reported co-payments agreed with administrative records with respect to GP office transactions, but not pharmaceutical co-payments. Research costs for the questionnaire-based method were less than one-third of the costs for the databases method. Conclusion A patient-completed questionnaire is feasible for capturing health care use and costs for patients with osteoarthritis, and data collected using it mostly agree with administrative databases. Caution should be exercised when applying unit costs and collecting co-payment data.

  10. Do Flexible Durable Goods Prices Undermine Sticky Price Models?

    OpenAIRE

    Robert Barsky; Christopher L. House; Miles Kimball

    2003-01-01

    Multi-sector sticky price models have surprising implications when durable goods have flexible prices. While in actual data the production of virtually all durables exhibits strong negative responses to monetary contractions, in dynamic general equilibrium models a monetary contraction causes the output of flexibly priced durables to expand. Indeed, in the polar case in which only nondurables have sticky prices, the negative comovement of durable and nondurable production exactly offsets and ...

  11. The EU-Turkey March 2016 Agreement As a Model

    DEFF Research Database (Denmark)

    Seeberg, Peter

    to the Arab Mediterranean and more specifically in the context of Libya, as and when political and security conditions in that country improve. The author recognizes that despite relevant criticism of the EU-Turkey deal, the agreement may well contain building blocks worth taking into consideration in future...

  12. An Inventory Model for Special Display Goods with Seasonal Demand

    Science.gov (United States)

    Kawakatsu, Hidefumi

    2010-10-01

    The present study discusses the retailer's optimal replenishment policy for seasonal products. The demand rate of seasonal merchandise such as clothes, sporting goods, children's toys and electrical home appearances tends to decrease with time after reaching its maximum value. In this study, we focus on "Special Display Goods", which are heaped up in end displays or special areas at retail stores. They are sold at a fast velocity when their quantity displayed is large, but are sold at a low velocity if the quantity becomes small. We develop the model with a finite time horizon (selling period) to determine the optimal replenishment policy, which maximizes the retailer's total profit. Numerical examples are presented to illustrate the theoretical underpinnings of the proposed model.

  13. Vulnerable Derivatives and Good Deal Bounds: A Structural Model

    DEFF Research Database (Denmark)

    Murgoci, Agatha

    2013-01-01

    can be obtained. We provide a link between the objective probability measure and the range of potential risk-neutral measures, which has an intuitive economic meaning. We also provide tight pricing bounds for European calls and show how to extend the call formula to pricing other financial products......We price vulnerable derivatives -- i.e. derivatives where the counterparty may default. These are basically the derivatives traded on the over-the-counter (OTC) markets. Default is modeled in a structural framework. The technique employed for pricing is good deal bounds (GDBs). The method imposes...... a new restriction in the arbitrage free model by setting upper bounds on the Sharpe ratios (SRs) of the assets. The potential prices that are eliminated represent unreasonably good deals. The constraint on the SR translates into a constraint on the stochastic discount factor. Thus, tight pricing bounds...

  14. A Distance Function Model with Good and Bad Outputs

    OpenAIRE

    2014-01-01

    We present an approach that pursues an adequate representation of product transformation possibilities for a technology generating, in addition to marketed (good) products, some environmentally detrimental non-marketed byproducts (bad outputs). As the shadow price of a non-marketed output depends on its marginal transformation rates with marketed outputs, representation of technological relationships between different groups of outputs deserves a particular attention. We model the technology ...

  15. Aspect Oriented Decision Making Model for Byzantine Agreement

    Directory of Open Access Journals (Sweden)

    V. Ramachandran

    2012-01-01

    Full Text Available Problem statement: The main aim of this research study is to develop an enhanced strategy for decision making whether to commit or rollback a request to a Web service in the presence of Byzantine faults using aspects. The proposed study extends the Lamport’s algorithm for Byzantine agreement to have an effective decision while handling the service request. When the service is initiated based on the request, its execution behaviour is being monitored before, after and at the time of execution and being handled with aspect concerns to provide the corresponding responses as input to the Lamport’s Byzantine agreement algorithm. The decision on the client requests is based on the outcome of the aspect advices before, after and around the execution of the services. Approach: This approach identifies the inception of the process which starts to exhibit abnormal behaviour before, after or during the execution of the service and instigates that helps in resolving the faulty service and identifies the root cause of the problem to rectify it. Aspect oriented advices do not require any external invocation as it executes with the service and hence no additional overhead involved in processing the service request. Results: In the existing methodology only the around advice decision is considered for reaching an agreement in the presence of Byzantine faults. An enhancement in the decision making process is proposed by including the state of the services: before, after and around advices of the aspects. Conclusion: The obtained experimental results based on the proposed methodology depict that the performance measure, Round Trip Time is slightly increased when compared with the existing Lamport’s algorithm for Byzantine Agreement and this performance overhead is not a major concern as the proposed approach produces an enhanced decision by considering aspect concerns and also determines the origin of the fault. The change in execution behaviour of Byzantine

  16. How Good Are Statistical Models at Approximating Complex Fitness Landscapes?

    Science.gov (United States)

    du Plessis, Louis; Leventhal, Gabriel E.; Bonhoeffer, Sebastian

    2016-01-01

    Fitness landscapes determine the course of adaptation by constraining and shaping evolutionary trajectories. Knowledge of the structure of a fitness landscape can thus predict evolutionary outcomes. Empirical fitness landscapes, however, have so far only offered limited insight into real-world questions, as the high dimensionality of sequence spaces makes it impossible to exhaustively measure the fitness of all variants of biologically meaningful sequences. We must therefore revert to statistical descriptions of fitness landscapes that are based on a sparse sample of fitness measurements. It remains unclear, however, how much data are required for such statistical descriptions to be useful. Here, we assess the ability of regression models accounting for single and pairwise mutations to correctly approximate a complex quasi-empirical fitness landscape. We compare approximations based on various sampling regimes of an RNA landscape and find that the sampling regime strongly influences the quality of the regression. On the one hand it is generally impossible to generate sufficient samples to achieve a good approximation of the complete fitness landscape, and on the other hand systematic sampling schemes can only provide a good description of the immediate neighborhood of a sequence of interest. Nevertheless, we obtain a remarkably good and unbiased fit to the local landscape when using sequences from a population that has evolved under strong selection. Thus, current statistical methods can provide a good approximation to the landscape of naturally evolving populations. PMID:27189564

  17. How Good Are Statistical Models at Approximating Complex Fitness Landscapes?

    Science.gov (United States)

    du Plessis, Louis; Leventhal, Gabriel E; Bonhoeffer, Sebastian

    2016-09-01

    Fitness landscapes determine the course of adaptation by constraining and shaping evolutionary trajectories. Knowledge of the structure of a fitness landscape can thus predict evolutionary outcomes. Empirical fitness landscapes, however, have so far only offered limited insight into real-world questions, as the high dimensionality of sequence spaces makes it impossible to exhaustively measure the fitness of all variants of biologically meaningful sequences. We must therefore revert to statistical descriptions of fitness landscapes that are based on a sparse sample of fitness measurements. It remains unclear, however, how much data are required for such statistical descriptions to be useful. Here, we assess the ability of regression models accounting for single and pairwise mutations to correctly approximate a complex quasi-empirical fitness landscape. We compare approximations based on various sampling regimes of an RNA landscape and find that the sampling regime strongly influences the quality of the regression. On the one hand it is generally impossible to generate sufficient samples to achieve a good approximation of the complete fitness landscape, and on the other hand systematic sampling schemes can only provide a good description of the immediate neighborhood of a sequence of interest. Nevertheless, we obtain a remarkably good and unbiased fit to the local landscape when using sequences from a population that has evolved under strong selection. Thus, current statistical methods can provide a good approximation to the landscape of naturally evolving populations.

  18. Trade in goods

    DEFF Research Database (Denmark)

    2006-01-01

    An analysis of the rules governing trade in goods under the GATT agreement and the Agreement on Safeguards......An analysis of the rules governing trade in goods under the GATT agreement and the Agreement on Safeguards...

  19. Vulnerable Derivatives and Good Deal Bounds: A Structural Model

    DEFF Research Database (Denmark)

    Murgoci, Agatha

    2013-01-01

    a new restriction in the arbitrage free model by setting upper bounds on the Sharpe ratios (SRs) of the assets. The potential prices that are eliminated represent unreasonably good deals. The constraint on the SR translates into a constraint on the stochastic discount factor. Thus, tight pricing bounds...... can be obtained. We provide a link between the objective probability measure and the range of potential risk-neutral measures, which has an intuitive economic meaning. We also provide tight pricing bounds for European calls and show how to extend the call formula to pricing other financial products...

  20. The Meaning of Goodness-of-Fit Tests: Commentary on "Goodness-of-Fit Assessment of Item Response Theory Models"

    Science.gov (United States)

    Thissen, David

    2013-01-01

    In this commentary, David Thissen states that "Goodness-of-fit assessment for IRT models is maturing; it has come a long way from zero." Thissen then references prior works on "goodness of fit" in the index of Lord and Novick's (1968) classic text; Yen (1984); Drasgow, Levine, Tsien, Williams, and Mead (1995); Chen and…

  1. MODELLING CHALLENGES TO FORECAST URBAN GOODS DEMAND FOR RAIL

    Directory of Open Access Journals (Sweden)

    Antonio COMI

    2015-12-01

    Full Text Available This paper explores the new research challenges for forecasting urban goods demand by rail. In fact, the growing interest to find urban logistics solutions for improving city sustainability and liveability, mainly due to the reduction of urban road accessibility and environmental constraints, has pushed to explore solutions alternative to the road. Multimodal urban logistics, based on the use of railway, seem an interesting alternative solution, but it remained mainly at conceptual level. Few studies have explored the factors, that push actors to find competitive such a system with respect to the road, and modelling framework for forecasting the relative demand. Therefore, paper reviews the current literature, investigates the factors involved in choosing such a mode, and finally, recalls a recent modelling framework and hence proposes some advancements that allow to point out the rail transport alternative.

  2. MEDIA AND DEVELOPMENT MODEL: FROM MODERNIZATION TO GOOD GOVERMENT

    Directory of Open Access Journals (Sweden)

    Ana Fernández Viso

    2013-04-01

    Full Text Available This paper describes and analyzes, from a historical perspective, the role that one of the central institutions of modernity, the media, has played in the development models and policies promoted by the actors of the international aid system since the 1950s. In addition, it presents and discusses the critiques to these models and policies made by intellectuals, governments, and civil society organizations from Southern countries, which have led to questioning the role of media in development processes and to redefining their inclusion in the development policies from the 1970s. Finally, the paper contributes some elements to reflect on the relationship between media, good government and development under the framework of the current governance reform strategies.

  3. Post-2020 climate agreements in the major economies assessed in the light of global models

    NARCIS (Netherlands)

    Tavoni, M.; Kriegler, E.; Riahi, K.; van Vuuren, D.F.; Aboumahboub, T.; Bowen, A.; Calvin, K.; Campiglio, E.; Kober, T.; Jewell, J.; Luderer, G.; Marangoni, G.; McCollum, D.; van Sluisveld, M.; Zimmer, A.; van der Zwaan, B.

    2014-01-01

    Integrated assessment models can help in quantifying the implications of international climate agreements and regional climate action. This paper reviews scenario results from model intercomparison projects to explore different possible outcomes of post-2020 climate negotiations, recently announced

  4. Post-2020 climate agreements in the major economies assessed in the light of global models

    NARCIS (Netherlands)

    Tavoni, Massimo; Kriegler, Elmar; Riahi, Keywan; Van Vuuren, Detlef P.|info:eu-repo/dai/nl/11522016X; Aboumahboub, Tino; Bowen, Alex; Calvin, Katherine; Campiglio, Emanuele; Kober, Tom; Jewell, Jessica; Luderer, Gunnar; Marangoni, Giacomo; Mccollum, David; Van Sluisveld, Mariësse; Zimmer, Anne; Van Der Zwaan, Bob

    2015-01-01

    Integrated assessment models can help in quantifying the implications of international climate agreements and regional climate action. This paper reviews scenario results from model intercomparison projects to explore different possible outcomes of post-2020 climate negotiations, recently announced

  5. Post-2020 climate agreements in the major economies assessed in the light of global models

    NARCIS (Netherlands)

    Tavoni, M.; Kriegler, E.; Riahi, K.; van Vuuren, D.F.; Aboumahboub, T.; Bowen, A.; Calvin, K.; Campiglio, E.; Kober, T.; Jewell, J.; Luderer, G.; Marangoni, G.; McCollum, D.; van Sluisveld, M.; Zimmer, A.; van der Zwaan, B.

    2014-01-01

    Integrated assessment models can help in quantifying the implications of international climate agreements and regional climate action. This paper reviews scenario results from model intercomparison projects to explore different possible outcomes of post-2020 climate negotiations, recently announced

  6. Post-2020 climate agreements in the major economies assessed in the light of global models

    NARCIS (Netherlands)

    Tavoni, Massimo; Kriegler, Elmar; Riahi, Keywan; Van Vuuren, Detlef P.; Aboumahboub, Tino; Bowen, Alex; Calvin, Katherine; Campiglio, Emanuele; Kober, Tom; Jewell, Jessica; Luderer, Gunnar; Marangoni, Giacomo; Mccollum, David; Van Sluisveld, Mariësse; Zimmer, Anne; Van Der Zwaan, Bob

    2015-01-01

    Integrated assessment models can help in quantifying the implications of international climate agreements and regional climate action. This paper reviews scenario results from model intercomparison projects to explore different possible outcomes of post-2020 climate negotiations, recently announced

  7. E-Learning Systems Support of Collaborative Agreements: A Theoretical Model

    Science.gov (United States)

    Aguirre, Sandra; Quemada, Juan

    2012-01-01

    This paper introduces a theoretical model for developing integrated degree programmes through e-learning systems as stipulated by a collaboration agreement signed by two universities. We have analysed several collaboration agreements between universities at the national, European, and transatlantic level as well as various e-learning frameworks. A…

  8. Good God?!? Lamentations as a model for mourning the loss of the good God.

    Science.gov (United States)

    Houck-Loomis, Tiffany

    2012-09-01

    This article will address the devastating psychological and social effects due to the loss of one's primary love-object, namely God in the case of faith communities and religious individuals. By using Melanie Klein's Object Relations Theory (Klein in Envy and gratitude and other works 1946/1963. The Free Press, New York, 1975a) as a way to enter the text of Lamentations, I will articulate an alternative reading that can serve as a model for Pastors and Educators to use when walking with individuals and communities through unspeakable losses. I will argue that Lamentations may be used as a tool for naming confounding depression and anxiety that stems from a damaged introjected object (one's personal God). This tool may provide individuals and communities a framework for placing anger and contempt upon God in order to re-assimilate this loved yet hated object, eventually leading toward healing and restoration of the self.

  9. Modeling morphosyntactic agreement in constituency-based parsing of modern Hebrew

    NARCIS (Netherlands)

    Tsarfaty, R.; Sima'an, K.

    2010-01-01

    We show that naïve modeling of morphosyn-tactic agreement in a Constituency-Based (CB) statistical parsing model is worse than none, whereas a linguistically adequate way of modeling inflectional morphology in CB parsing leads to improved performance. In particular, we show that an extension of the

  10. Group size effects in two repeated game models of a global climate agreement

    Energy Technology Data Exchange (ETDEWEB)

    Helland, Leif

    2002-07-01

    What levels of total abatement can one hope for in a global climate agreement. Some potential answers to this question are provided by game theory. This working paper contains a critical discussion of two (prominent) game ,models that answer the question quite pessimistically. Both models take the n-person, infinitely repeated prisoner's dilemma game as their point of departure. The first model is a full information model and utilises the motion of a weakly re negotiation proof equilibrium. This results in the (maybe counterintuitive) prediction that an agreement that can provide high utility to the group will attract less total abatement than an agreement that can only provide low utility to the group. The second model assumes imperfect public information and utilises the notion of a trigger level equilibrium. This results in the (more intuitive) prediction that the level of total abatements will increase with improved verification techniques for a given player set. Still the level of total abatements decrease with an increasing player set for a given verification technique. Empirical implications of the two models are identified and it is argued that one should confront these with experimentally generated data in order to discriminate between the models. One reason for this is that historical data on abatement efforts in a global climate agreement do not exist since no such agreement has entered into force yet. (Author)

  11. Agreement between PRE2DUP register data modeling method and comprehensive drug use interview among older persons

    Directory of Open Access Journals (Sweden)

    Taipale H

    2016-10-01

    Full Text Available Heidi Taipale,1–4,* Antti Tanskanen,3–5,* Marjaana Koponen,1,2 Anna-Maija Tolppanen,2,6 Jari Tiihonen,3,4 Sirpa Hartikainen1,2,7 1Kuopio Research Centre of Geriatric Care, University of Eastern Finland, 2School of Pharmacy, University of Eastern Finland, Kuopio, Finland; 3Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden; 4Department of Forensic Psychiatry, Niuvanniemi Hospital, University of Eastern Finland, Kuopio, 5National Institute for Health and Welfare, Helsinki, 6Research Centre for Comparative Effectiveness and Patient Safety (RECEPS, University of Eastern Finland, 7Department of Psychiatry, Kuopio University Hospital, Kuopio, Finland *These authors contributed equally to this work. Background: PRE2DUP is a modeling method that generates drug use periods (ie, when drug use started and ended from drug purchases recorded in dispensing-based register data. It is based on the evaluation of personal drug purchasing patterns and considers hospital stays, possible stockpiling of drugs, and package information. Objective: The objective of this study was to investigate person-level agreement between self-reported drug use in the interview and drug use modeled from dispensing data with PRE2DUP method for various drug classes used by older persons. Methods: Self-reported drug use was assessed from the GeMS Study including a random sample of persons aged ≥75 years from the city of Kuopio, Finland, in 2006. Drug purchases recorded in the Prescription register data of these persons were modeled to determine drug use periods with PRE2DUP modeling method. Agreement between self-reported drug use on the interview date and drug use calculated from register-based data was compared in order to find the frequently used drugs and drug classes, which was evaluated by Cohen’s kappa. Kappa values 0.61–0.80 were considered to represent good and 0.81–1.00 as very good agreement.Results: Among 569 participants with mean age

  12. Agent-based models of strategies for the emergence and evolution of grammatical agreement.

    Science.gov (United States)

    Beuls, Katrien; Steels, Luc

    2013-01-01

    Grammatical agreement means that features associated with one linguistic unit (for example number or gender) become associated with another unit and then possibly overtly expressed, typically with morphological markers. It is one of the key mechanisms used in many languages to show that certain linguistic units within an utterance grammatically depend on each other. Agreement systems are puzzling because they can be highly complex in terms of what features they use and how they are expressed. Moreover, agreement systems have undergone considerable change in the historical evolution of languages. This article presents language game models with populations of agents in order to find out for what reasons and by what cultural processes and cognitive strategies agreement systems arise. It demonstrates that agreement systems are motivated by the need to minimize combinatorial search and semantic ambiguity, and it shows, for the first time, that once a population of agents adopts a strategy to invent, acquire and coordinate meaningful markers through social learning, linguistic self-organization leads to the spontaneous emergence and cultural transmission of an agreement system. The article also demonstrates how attested grammaticalization phenomena, such as phonetic reduction and conventionalized use of agreement markers, happens as a side effect of additional economizing principles, in particular minimization of articulatory effort and reduction of the marker inventory. More generally, the article illustrates a novel approach for studying how key features of human languages might emerge.

  13. Agent-based models of strategies for the emergence and evolution of grammatical agreement.

    Directory of Open Access Journals (Sweden)

    Katrien Beuls

    Full Text Available Grammatical agreement means that features associated with one linguistic unit (for example number or gender become associated with another unit and then possibly overtly expressed, typically with morphological markers. It is one of the key mechanisms used in many languages to show that certain linguistic units within an utterance grammatically depend on each other. Agreement systems are puzzling because they can be highly complex in terms of what features they use and how they are expressed. Moreover, agreement systems have undergone considerable change in the historical evolution of languages. This article presents language game models with populations of agents in order to find out for what reasons and by what cultural processes and cognitive strategies agreement systems arise. It demonstrates that agreement systems are motivated by the need to minimize combinatorial search and semantic ambiguity, and it shows, for the first time, that once a population of agents adopts a strategy to invent, acquire and coordinate meaningful markers through social learning, linguistic self-organization leads to the spontaneous emergence and cultural transmission of an agreement system. The article also demonstrates how attested grammaticalization phenomena, such as phonetic reduction and conventionalized use of agreement markers, happens as a side effect of additional economizing principles, in particular minimization of articulatory effort and reduction of the marker inventory. More generally, the article illustrates a novel approach for studying how key features of human languages might emerge.

  14. Dynamic Processes in Network Goods: Modeling, Analysis and Applications

    Science.gov (United States)

    Paothong, Arnut

    2013-01-01

    The network externality function plays a very important role in the study of economic network industries. Moreover, the consumer group dynamic interactions coupled with network externality concept is going to play a dominant role in the network goods in the 21st century. The existing literature is stemmed on a choice of externality function with…

  15. Traumatic Coagulopathy: Where are the Good Experimental Models?

    Science.gov (United States)

    2008-10-01

    factor model,24 a mathematical model of dilutional coagulopathy,17 gene therapy enhanced clotting in a murine von Willebrand model20 and a sheep model...1997;77:905–910. 35. Lei TC, Scott DW. Induction of tolerance to factor VIII inhibitors by gene therapy with immunodominant A2 and C2 domains presented by B...included two rabbit model studies,15,24 focused on the role of factor VII in an endotoxin model15 and antibody-induced hemophilia in a von Wille- brand

  16. How good are one-dimensional Josephson junction models?

    DEFF Research Database (Denmark)

    Lomdahl, P. S.; Olsen, O.H.; Eilbeck, J. C.

    1985-01-01

    A two-dimensional model of Josephson junctions of overlap type is presented and shown to reduce to the usual one-dimensional (1D) model in the limit of a very narrow junction. Comparisons between the stability limits for fluxon reflection obtained from the two models suggest that the many results...

  17. An introduction to good practices in cognitive modeling

    NARCIS (Netherlands)

    A. Heathcote; S.D. Brown; E.-J. Wagenmakers

    2015-01-01

    Cognitive modeling can provide important insights into the underlying causes of behavior, but the validity of those insights rests on careful model development and checking. We provide guidelines on five important aspects of the practice of cognitive modeling: parameter recovery, testing selective i

  18. The Web economy: goods, users, models and policies

    CERN Document Server

    Vafopoulos, Michalis

    2011-01-01

    Web emerged as an antidote to the rapidly increasing quantity of accumulated knowledge and become successful because it facilitates massive participation and communication with minimum costs. Today, its enormous impact, scale and dynamism in time and space make very difficult (and sometimes impossible) to measure and anticipate the effects in human society. In addition to that, we demand from the Web to be fast, secure, reliable, all-inclusive and trustworthy in any transaction. The scope of the present article is to review a part of the Web economy literature that will help us to identify its major participants and their functions. The goal is to understand how the Web economy differs from the traditional setting and what implications have these differences. Secondarily, we attempt to establish a minimal common understanding about the incentives and properties of the Web economy. In this direction the concept of Web Goods and a new classification of Web Users are introduced and analyzed This article, is not,...

  19. Good modeling practice for PAT applications: propagation of input uncertainty and sensitivity analysis.

    Science.gov (United States)

    Sin, Gürkan; Gernaey, Krist V; Lantz, Anna Eliasson

    2009-01-01

    The uncertainty and sensitivity analysis are evaluated for their usefulness as part of the model-building within Process Analytical Technology applications. A mechanistic model describing a batch cultivation of Streptomyces coelicolor for antibiotic production was used as case study. The input uncertainty resulting from assumptions of the model was propagated using the Monte Carlo procedure to estimate the output uncertainty. The results showed that significant uncertainty exists in the model outputs. Moreover the uncertainty in the biomass, glucose, ammonium and base-consumption were found low compared to the large uncertainty observed in the antibiotic and off-gas CO(2) predictions. The output uncertainty was observed to be lower during the exponential growth phase, while higher in the stationary and death phases - meaning the model describes some periods better than others. To understand which input parameters are responsible for the output uncertainty, three sensitivity methods (Standardized Regression Coefficients, Morris and differential analysis) were evaluated and compared. The results from these methods were mostly in agreement with each other and revealed that only few parameters (about 10) out of a total 56 were mainly responsible for the output uncertainty. Among these significant parameters, one finds parameters related to fermentation characteristics such as biomass metabolism, chemical equilibria and mass-transfer. Overall the uncertainty and sensitivity analysis are found promising for helping to build reliable mechanistic models and to interpret the model outputs properly. These tools make part of good modeling practice, which can contribute to successful PAT applications for increased process understanding, operation and control purposes.

  20. De praeceptis ferendis: good practice in multi-model ensembles

    Directory of Open Access Journals (Sweden)

    I. Kioutsioukis

    2014-06-01

    Full Text Available Ensembles of air quality models have been formally and empirically shown to outperform single models in many cases. Evidence suggests that ensemble error is reduced when the members form a diverse and accurate ensemble. Diversity and accuracy are hence two factors that should be taken care of while designing ensembles in order for them to provide better predictions. There exists a trade-off between diversity and accuracy for which one cannot be gained without expenses of the other. Theoretical aspects like the bias-variance-covariance decomposition and the accuracy-diversity decomposition are linked together and support the importance of creating ensemble that incorporates both the elements. Hence, the common practice of unconditional averaging of models without prior manipulation limits the advantages of ensemble averaging. We demonstrate the importance of ensemble accuracy and diversity through an inter-comparison of ensemble products for which a sound mathematical framework exists, and provide specific recommendations for model selection and weighting for multi model ensembles. To this end we have devised statistical tools that can be used for diagnostic evaluation of ensemble modelling products, complementing existing operational methods.

  1. Post-2020 climate agreements in the major economies assessed in the light of global models

    OpenAIRE

    Tavoni, Massimo; Kriegler, Elmar; Riahi, Keywan (Prof. Dr. ); van Vuuren, Detlef P.; Aboumahboub, Tino; Bowen, Alex; Calvin, Katherine; Campiglio, Emanuele; Kober, Tom; Jewell, Jessica; Luderer, Gunnar; Marangoni, Giacomo; McCollum, David; van Sluisveld, Mariësse; Zimmer, Anne

    2014-01-01

    Integrated assessment models can help in quantifying the implications of international climate agreements and regional climate action. This paper reviews scenario results from model intercomparison projects to explore different possible outcomes of post-2020 climate negotiations, recently announced pledges and their relation to the 2 °C target. We provide key information for all the major economies, such as the year of emission peaking, regional carbon budgets and emissions allowances. We hig...

  2. Simulation with Ideal Switch Models Combined with Measured Loss Data Provides a Good Estimate of Power Loss

    Institute of Scientific and Technical Information of China (English)

    StigMunk-Nielsen; Lucian; N; Tutelea; Ulrik; Jager

    2007-01-01

    Ideally, converter losses should be determined without using an excessive amount of simulation time. State-of-the-art power semiconductor models provide good accuracy,unfortunately they often require a very long simulation time. This paper describes how to estimate power losses from simulation using ideal switches combined with measured power loss data. The semiconductor behavior is put into a look-up table,which replaces the advanced semiconductor models and shortens the simulation time.To extract switching and conduction losses, a converter is simulated and the semiconductor power losses are estimated. Measurement results on a laboratory converter are compared with the estimated losses and a good agreement is shown. Using the ideal switch simulation and the post processing power estimation program,a ten to twenty fold increase in simulation speed is obtained,compared to simulations using advanced models of semiconductors.

  3. Goodness-of-fit tests in mixed models

    KAUST Repository

    Claeskens, Gerda

    2009-05-12

    Mixed models, with both random and fixed effects, are most often estimated on the assumption that the random effects are normally distributed. In this paper we propose several formal tests of the hypothesis that the random effects and/or errors are normally distributed. Most of the proposed methods can be extended to generalized linear models where tests for non-normal distributions are of interest. Our tests are nonparametric in the sense that they are designed to detect virtually any alternative to normality. In case of rejection of the null hypothesis, the nonparametric estimation method that is used to construct a test provides an estimator of the alternative distribution. © 2009 Sociedad de Estadística e Investigación Operativa.

  4. Dynamics in a nonlinear Keynesian good market model

    Energy Technology Data Exchange (ETDEWEB)

    Naimzada, Ahmad, E-mail: ahmad.naimzada@unimib.it [Department of Economics, Quantitative Methods and Management, University of Milano-Bicocca, U7 Building, Via Bicocca degli Arcimboldi 8, 20126 Milano (Italy); Pireddu, Marina, E-mail: marina.pireddu@unimib.it [Department of Mathematics and Applications, University of Milano-Bicocca, U5 Building, Via Cozzi 55, 20125 Milano (Italy)

    2014-03-15

    In this paper, we show how a rich variety of dynamical behaviors can emerge in the standard Keynesian income-expenditure model when a nonlinearity is introduced, both in the cases with and without endogenous government spending. A specific sigmoidal functional form is used for the adjustment mechanism of income with respect to the excess demand, in order to bound the income variation. With the aid of analytical and numerical tools, we investigate the stability conditions, bifurcations, as well as periodic and chaotic dynamics. Globally, we study multistability phenomena, i.e., the coexistence of different kinds of attractors.

  5. La opacidad de los acuerdos generales de bienes y servicios en España Opacity of general agreements on goods and services in Spain

    Directory of Open Access Journals (Sweden)

    Román Andrés Umaña Peña

    2006-06-01

    Full Text Available Objetivo: Explorar la intensidad del debate parlamentario sobre el Acuerdo General de Comercio de Servicios (AGCS asumido por España ante la Organización Mundial del Comercio (OMC, y compararla con la del Acuerdo General de Bienes (GATT. Métodos: Búsqueda sistemática y análisis del contenido de todas las iniciativas parlamentarias sobre AGCS y GATT realizadas entre 1979 y 2004 en el Congreso de los Diputados y el Senado. Se calculó la frecuencia y porcentaje de iniciativas parlamentarias de ambos temas, resultado de su tramitación y tipo de iniciativa. Resultados: Se presentaron 185 iniciativas parlamentarias sobre los acuerdos multilaterales de bienes y servicios, de las que 120 se referían al GATT, 8 al AGCS y 57 a ambos acuerdos. La mayoría de las iniciativas no fueron discutidas (GATT, 71%; GATS, 55,4% o estuvieron sujetas a un debate político en el que apenas se dieron intervenciones por parte de los grupos parlamentarios. Conclusiones: A pesar de las implicaciones del acuerdo multilateral de servicios para la política sanitaria española, éste se ha asumido con escaso debate parlamentario previo, incluso menos que en el caso de su homólogo sobre bienes. Se requiere en este tema una intensificación de la función de control al gobierno.Objective: To explore the intensity of the debate in the Spanish Parliament on the General Agreement on Trade in Services (GATS developed by Spain and the World Trade Organization, and to compare it with the debate on the General Agreement on Tariffs and Trade (GATT. Methods: A systematic search and content analysis were performed of all parliamentary initiatives on GATS and GATT undertaken from 1979 to 2004 in the Spanish Parliament and Senate. The frequency and percentages of initiatives on both issues were calculated, and the final result and kinds of initiative were analyzed. Results: A total of 185 initiatives were presented in the Spanish Parliament on these agreements, of which 120 were

  6. The importance of information goods abstraction levels for information commerce process models

    NARCIS (Netherlands)

    Wijnhoven, Fons

    2002-01-01

    A process model, in the context of e-commerce, is an organized set of activities for the creation, (re-)production, trade and delivery of goods. Electronic commerce studies have created important process models for the trade of physical goods via Internet. These models are not easily suitable for th

  7. Good modelling practice in applying computational fluid dynamics for WWTP modelling.

    Science.gov (United States)

    Wicklein, Edward; Batstone, Damien J; Ducoste, Joel; Laurent, Julien; Griborio, Alonso; Wicks, Jim; Saunders, Stephen; Samstag, Randal; Potier, Olivier; Nopens, Ingmar

    2016-01-01

    Computational fluid dynamics (CFD) modelling in the wastewater treatment (WWT) field is continuing to grow and be used to solve increasingly complex problems. However, the future of CFD models and their value to the wastewater field are a function of their proper application and knowledge of their limits. As has been established for other types of wastewater modelling (i.e. biokinetic models), it is timely to define a good modelling practice (GMP) for wastewater CFD applications. An International Water Association (IWA) working group has been formed to investigate a variety of issues and challenges related to CFD modelling in water and WWT. This paper summarizes the recommendations for GMP of the IWA working group on CFD. The paper provides an overview of GMP and, though it is written for the wastewater application, is based on general CFD procedures. A forthcoming companion paper to provide specific details on modelling of individual wastewater components forms the next step of the working group.

  8. Continuous blood pressure monitoring via non-invasive radial artery applanation tonometry and invasive arterial catheter demonstrates good agreement in patients undergoing colon carcinoma surgery.

    Science.gov (United States)

    Sun, Jing; Chen, Hanjian; Zheng, Jun; Mao, Bin; Zhu, Shengmei; Feng, Jingyi

    2016-12-20

    Radial artery applanation tonometry (RAAT) has been developed and utilized for continuous arterial pressure monitoring. However, evidence is lacking to clinically verify the RAAT technology and identify appropriate patient groups before routine clinical use. This study aims to evaluate the RAAT technology by comparing systolic blood pressure (SBP), mean blood pressure (MBP) and diastolic blood pressure (DBP) values in patients undergoing colon carcinoma surgery. Blood Pressure (BP) values obtained via RAAT (TL-300, Tensys Medical Inc., San Diego, CA, USA) and conventional arterial catheterization from 30 colon carcinoma surgical patients were collected and compared via Bland-Atman method, linear regression and 4-quadrant plot concordance analysis. For SBPs, MBPs and DBPs, means of the differences (±standard deviation; 95% limits of agreement) were -0.9 (±7.6; -15.7 to 13.9) mmHg, 3.1 (±6.5; -9.6 to 15.8) mmHg and 4.3 (±7.4; -10.3 to 18.8) mmHg, respectively. Linear regression coefficients of determination were 0.8706 for SBPs, 0.8353 for MBPs and 0.6858 for DBPs. Four-quadrant concordance correlation coefficients were 0.8740, 0.8522 and 0.7108 for SBPs, MBPs and DBPs, respectively. A highly selected patient collective undergoing colon carcinoma surgery was studied. BP measurements obtained via the TL-300 had clinically acceptable agreement with that acquired invasively using an arterial catheter. For use in clinical routine, it is necessary to take measures for improvement regarding movement artifacts and dilution of noise. A large sample size of patients under various conditions is also needed to further evaluate the RAAT technology before clinically routine use.

  9. Model of an International Environmental Agreement among Asymmetric Nations applied to Debris Mitigation

    CERN Document Server

    Singer, Michael J

    2010-01-01

    We investigate how ideas from the International Environmental Agreement (IEA) literature can be applied to the problem of space debris mitigation. The problem of space debris is similar to other international environmental problems in that there is a potential for a tragedy of the commons effect--individual nations bear all the cost of their mitigation measures but share only a fraction of the benefit. Consequently, nations have a tendency to underinvest in mitigation. Coalitions of nations, brought together by IEAs, have the potential to lessen the tragedy of the commons effect by pooling the costs and benefits of mitigation. This work brings together two recent modeling advances: i) a game theoretic model for studying the potential gains from IEA cooperation between nations with asymmetric costs and benefits, ii) an orbital debris model that gives the societal cost that specific actions, such as failing to deorbit an inactive satellite, have on the environment. We combine these two models with empirical lau...

  10. Model Checking Probabilistic Real-Time Properties for Service-Oriented Systems with Service Level Agreements

    Directory of Open Access Journals (Sweden)

    Christian Krause

    2011-11-01

    Full Text Available The assurance of quality of service properties is an important aspect of service-oriented software engineering. Notations for so-called service level agreements (SLAs, such as the Web Service Level Agreement (WSLA language, provide a formal syntax to specify such assurances in terms of (legally binding contracts between a service provider and a customer. On the other hand, formal methods for verification of probabilistic real-time behavior have reached a level of expressiveness and efficiency which allows to apply them in real-world scenarios. In this paper, we suggest to employ the recently introduced model of Interval Probabilistic Timed Automata (IPTA for formal verification of QoS properties of service-oriented systems. Specifically, we show that IPTA in contrast to Probabilistic Timed Automata (PTA are able to capture the guarantees specified in SLAs directly. A particular challenge in the analysis of IPTA is the fact that their naive semantics usually yields an infinite set of states and infinitely-branching transitions. However, using symbolic representations, IPTA can be analyzed rather efficiently. We have developed the first implementation of an IPTA model checker by extending the PRISM tool and show that model checking IPTA is only slightly more expensive than model checking comparable PTA.

  11. Modeled riparian stream shading: Agreement with field measurements and sensitivity to riparian conditions

    Science.gov (United States)

    Li, Guoyuan; Jackson, C. Rhett; Kraseski, Kristin A.

    2012-03-01

    SummaryShading by riparian vegetation and streambanks reduces incident solar radiation on channels, and accurate estimation of riparian shading through the sun's daily arc is a critical aspect of water temperature and dissolved oxygen modeling. However, riparian trees exhibit complex shapes, often leaning and growing branches preferentially over channels to utilize the light resource. As a result, riparian vegetation cast complex shadows with significant variability at the scale of meters. Water quality models necessarily simplify factors affecting shading at the expense of accuracy. All models must make simplifying assumptions about tree geometry. Reach-based models must average channel azimuth and riparian conditions over each reach, and GIS models must also accept errors in the channel-riparian relationships caused by the DEM grid detail. We detail minor improvements to existing shade models and create a model (SHADE2) that calculates shading ratio (%) by riparian canopy at any time and location for given stream characteristics including stream azimuth, stream width, canopy height, canopy overhang, and height of maximum canopy overhang. Sensitivity of simulated shade to these variables is explored. We also present a new field photographic technique for quantifying shade and use this technique to provide data to test the SHADE2 algorithm. Twenty-four independent shade measurements were made in eight channels with mature hardwood riparian trees at different times of the summer and at different times of the day. Agreement between measured and modeled shade was excellent, with r2 of 0.90.

  12. The empirical likelihood goodness-of-fit test for regression model

    Institute of Scientific and Technical Information of China (English)

    Li-xing ZHU; Yong-song QIN; Wang-li XU

    2007-01-01

    Goodness-of-fit test for regression modes has received much attention in literature. In this paper, empirical likelihood (EL) goodness-of-fit tests for regression models including classical parametric and autoregressive (AR) time series models are proposed. Unlike the existing locally smoothing and globally smoothing methodologies, the new method has the advantage that the tests are self-scale invariant and that the asymptotic null distribution is chi-squared. Simulations are carried out to illustrate the methodology.

  13. Model Checking Probabilistic Real-Time Properties for Service-Oriented Systems with Service Level Agreements

    CERN Document Server

    Krause, Christian; 10.4204/EPTCS.73.8

    2011-01-01

    The assurance of quality of service properties is an important aspect of service-oriented software engineering. Notations for so-called service level agreements (SLAs), such as the Web Service Level Agreement (WSLA) language, provide a formal syntax to specify such assurances in terms of (legally binding) contracts between a service provider and a customer. On the other hand, formal methods for verification of probabilistic real-time behavior have reached a level of expressiveness and efficiency which allows to apply them in real-world scenarios. In this paper, we suggest to employ the recently introduced model of Interval Probabilistic Timed Automata (IPTA) for formal verification of QoS properties of service-oriented systems. Specifically, we show that IPTA in contrast to Probabilistic Timed Automata (PTA) are able to capture the guarantees specified in SLAs directly. A particular challenge in the analysis of IPTA is the fact that their naive semantics usually yields an infinite set of states and infinitely...

  14. RRM: An incentive reputation model for promoting good behaviors in distributed systems

    Institute of Scientific and Technical Information of China (English)

    ZHANG Hong; DUAN HaiXin; LIU Wu

    2008-01-01

    Reputation systems represent soft security mechanisms that complement tradi tional information security mechanisms. They are now widely used in online e-commerce markets and communities in order to stimulate good behaviors as well as to restrainadverse behaviors. This paper analyzes the limitations of the conversational reputation models and proposes an incentive reputation model called the resilient reputation model (RRM) for the distributed reputation systems. The objective of this reputation model is not only to encourage the users to provide good services and, therefore, to maximize the probability of good transaction outcomes, but also to punish those adverse users who are trying to manipulate the application systems. The simulation results indicate that the proposed reputation model (RRM) could effectively resist against the common adverse behaviors, while protecting the profits of sincere users from being blemished by those adversaries.

  15. Unifying distance-based goodness-of-fit indicators for hydrologic model assessment

    Science.gov (United States)

    Cheng, Qinbo; Reinhardt-Imjela, Christian; Chen, Xi; Schulte, Achim

    2014-05-01

    The goodness-of-fit indicator, i.e. efficiency criterion, is very important for model calibration. However, recently the knowledge about the goodness-of-fit indicators is all empirical and lacks a theoretical support. Based on the likelihood theory, a unified distance-based goodness-of-fit indicator termed BC-GED model is proposed, which uses the Box-Cox (BC) transformation to remove the heteroscedasticity of model errors and the generalized error distribution (GED) with zero-mean to fit the distribution of model errors after BC. The BC-GED model can unify all recent distance-based goodness-of-fit indicators, and reveals the mean square error (MSE) and the mean absolute error (MAE) that are widely used goodness-of-fit indicators imply statistic assumptions that the model errors follow the Gaussian distribution and the Laplace distribution with zero-mean, respectively. The empirical knowledge about goodness-of-fit indicators can be also easily interpreted by BC-GED model, e.g. the sensitivity to high flow of the goodness-of-fit indicators with large power of model errors results from the low probability of large model error in the assumed distribution of these indicators. In order to assess the effect of the parameters (i.e. the BC transformation parameter λ and the GED kurtosis coefficient β also termed the power of model errors) of BC-GED model on hydrologic model calibration, six cases of BC-GED model were applied in Baocun watershed (East China) with SWAT-WB-VSA model. Comparison of the inferred model parameters and model simulation results among the six indicators demonstrates these indicators can be clearly separated two classes by the GED kurtosis β: β >1 and β ≤ 1. SWAT-WB-VSA calibrated by the class β >1 of distance-based goodness-of-fit indicators captures high flow very well and mimics the baseflow very badly, but it calibrated by the class β ≤ 1 mimics the baseflow very well, because first the larger value of β, the greater emphasis is put on

  16. Model for improving safety in transporting dangerous goods for the Serbian Army

    Directory of Open Access Journals (Sweden)

    Dragan S. Kostadinović

    2012-07-01

    Full Text Available Design and improvement of the safety of transport of dangerous goods is a multidimensional and dynamic process which can be implemented using several different methods and techniques. In defining the model of improving the safety of transport of dangerous goods for the purposes of the Serbian Army, the Deming's approach to quality management system has been used. The analysis of the existing organization of transport of dangerous goods in the Army of Serbia has established the basic causes that affect the reduction in security as well as specific measures to be taken to improve the safety of transport of dangerous goods in the Serbian Army. The benchmark concept, widely used in the world, especially among organizations dealing with the same kind of logistic services, has been applied to indentify measures to improve the safety of transport of dangerous goods in the Serbian Army.

  17. Optimizing hurricane disaster relief goods distribution: model development and application with respect to planning strategies.

    Science.gov (United States)

    Horner, Mark W; Downs, Joni A

    2010-07-01

    Over the last few years, hurricane emergencies have been among the most pervasive major disruptions in the United States, particularly in the south-east region of the country. A key aspect of managing hurricane disasters involves logistical planning to facilitate the distribution and transportation of relief goods to populations in need. This study shows how a variant of the capacitated warehouse location model can be used to manage the flow of goods shipments to people in need. In this application, the model is used with protocols set forth in Florida's Comprehensive Emergency Plan and tested in a smaller city in north Florida. Scenarios explore the effects of alternate goods distribution strategies on the provision of disaster relief. Results show that measures describing people's accessibility to relief goods are affected by the distribution infrastructure used to provide relief, as well as assumptions made regarding the population(s) assumed to be in need of aid.

  18. Sensing Story Elements and Structure in Good Literature, the Models for Children's Writing.

    Science.gov (United States)

    Vilscek, Elaine

    1990-01-01

    Discusses how teachers can build upon childrens' natural sense of story, identify good books to serve as models of story elements and structure, and highlight the worth of an author's or illustrator's techniques of story craft as models for improved student writing. (SR)

  19. Local and omnibus goodness-of-fit tests in classical measurement error models

    KAUST Repository

    Ma, Yanyuan

    2010-09-14

    We consider functional measurement error models, i.e. models where covariates are measured with error and yet no distributional assumptions are made about the mismeasured variable. We propose and study a score-type local test and an orthogonal series-based, omnibus goodness-of-fit test in this context, where no likelihood function is available or calculated-i.e. all the tests are proposed in the semiparametric model framework. We demonstrate that our tests have optimality properties and computational advantages that are similar to those of the classical score tests in the parametric model framework. The test procedures are applicable to several semiparametric extensions of measurement error models, including when the measurement error distribution is estimated non-parametrically as well as for generalized partially linear models. The performance of the local score-type and omnibus goodness-of-fit tests is demonstrated through simulation studies and analysis of a nutrition data set.

  20. Modeling hidden dynamics of multimodal cues for spontaneous agreement and disagreement recognition

    NARCIS (Netherlands)

    Bousmalis, Konstantinos; Morencey, Louis–Philippe; Pantic, Maja

    2011-01-01

    This paper attempts to recognize spontaneous agreement and disagreement based only on nonverbal multi-modal cues. Related work has mainly used verbal and prosodic cues. We demonstrate that it is possible to correctly recognize agreement and disagreement without the use of verbal context (i.e. words,

  1. Is Technology Good for Us? A Eudaimonic Meta-Model for Evaluating the Contributive Capability of Technologies for a Good Life.

    Science.gov (United States)

    Spence, Edward H

    2011-12-01

    The title refers to the question addressed in this paper, namely, to what degree if any technology, including nanotechnologies, in the form of products and processes, is capable of contributing to a good life. To answer that question, the paper will develop a meta-normative model whose primary purpose is to determine the essential conditions that any normative theory of the Good Life and Technology (T-GLAT) must adequately address in order to be able to account for, explain and evaluate the Contributive Capability of Technology for a Good Life (CCT-GL). By CCT-GL understand the capability of any technological product or process in its design and/or its use to contribute in some way, if any, to the good life of individuals and society at large. In this paper, the all-embracing term "technology" will be used to refer to both the products and processes of different technologies.

  2. TOWARDS A CONCEPTUAL FRAMEWORK OF ISLAMIC LEADERSHIP SUCCESSOR'S ATTRIBUTES MODEL AND GOOD GOVERNANCE

    Directory of Open Access Journals (Sweden)

    Naji Zuhair Alsarhi

    2015-12-01

    Full Text Available The purpose of this paper is to propose a conceptual model that explains the relationship between Islamic leadership successionpersonalityattributes and good governance. The paper sources information from an extensive search of literature to design a conceptual model of Islamic leadership succession (personal attributes & governmental characteristics of Succession and good governance. The model will provide an integration of relationships that will add valuable insights into improved leadership succession theory in the related literature. The paper may assist particularly policy makers and strategists to focus on new possibilities of leadership successors attributes that will lead to improved governance as well as government performance in the world in general, and the Palestine community, in particular.

  3. Wastewater Treatment Model in Washing Stations for Vehicles Transporting Dangerous Goods

    Directory of Open Access Journals (Sweden)

    Robert Muha

    2004-09-01

    Full Text Available Car washing is a task performed by every passenger carowner more or less frequently, mainly to achieve a finer appearanceof the vehicle rather than for the need for cleanness.In the transport business, the owner's concern is to presentclean and orderly vehicles on the road as a relevant external elementof order, implying good corporate image to customers. Onthe other hand, in dangerous goods transportation there areother reasons requiring special technology of washing, applicableto the transport means used, depending on the change oftype of goods in carriage, the preliminary preparation of a vehicleto load the cargo, or to undergo maintenance.Water applied in the technology of washing collects the residueof goods carried in the vehicle and is polluted to such an extentthat it cannot be discharged into sewers - nor directly into awatercourse - without previous treatment.The paper presents a solution model and a sequence oftechnological procedures involved in an efficient treatment ofthe polluted wastewater in tank wash stations, in which mostlyvehicles carrying ADR goods are washed.

  4. Good Corporate Governance and Predicting Financial Distress Using Logistic and Probit Regression Model

    Directory of Open Access Journals (Sweden)

    Juniarti Juniarti

    2013-01-01

    Full Text Available The study aims to prove whether good corporate governance (GCG is able to predict the probability of companies experiencing financial difficulties. Financial ratios that traditionally used for predicting bankruptcy remains used in this study. Besides, this study also compares logit and probit regression models, which are widely used in research related accounting bankruptcy prediction. Both models will be compared to determine which model is more superior. The sample in this study is the infrastructure, transportation, utilities & trade, services and hotels companies experiencing financial distress in the period 2008-2011. The results show that GCG and other three variables control i.e DTA, CR and company category do not prove significantly to predict the probability of companies experiencing financial difficulties. NPM, the only variable that proved significantly distinguishing healthy firms and distress. In general, logit and probit models do not result in different conclusions. Both of the models confirm the goodness of fit of models and the results of hypothesis testing. In terms of classification accuracy, logit model proves more accurate predictions than the probit models.

  5. New methods to measure and model logistics and goods effects by the use of the CLG-DSS Model

    DEFF Research Database (Denmark)

    Salling, Kim Bang; Jensen, Anders Vestergaard

    2004-01-01

    This paper concerns the assessment and modelling of so-called logistics and goods effects (LG-effects) as part of a wider economic analysis by use of the developed CLG-DSS model. The results presented are based an on-going study, Task 9 about evaluation modelling and decision support systems (DSS...... The aim of this paper is to present these four LG-effects with a special emphasis on a possible way of modelling these and interpreting their importance. The calculations are carried out by using the CLG-DSS model and case studies concerning the fixed links across the Great Belt and Øresund....... It is proposed to model the effects in two ways. First the paper presents a combined method modelling the four effects into one aggregate effect characterized by the goods-related time benefits. Second the paper describes a more refined, disaggregate method approach that, however, at this stage only concerns...

  6. A Monte Carlo-adjusted goodness-of-fit test for parametric models describing spatial point patterns

    KAUST Repository

    Dao, Ngocanh

    2014-04-03

    Assessing the goodness-of-fit (GOF) for intricate parametric spatial point process models is important for many application fields. When the probability density of the statistic of the GOF test is intractable, a commonly used procedure is the Monte Carlo GOF test. Additionally, if the data comprise a single dataset, a popular version of the test plugs a parameter estimate in the hypothesized parametric model to generate data for theMonte Carlo GOF test. In this case, the test is invalid because the resulting empirical level does not reach the nominal level. In this article, we propose a method consisting of nested Monte Carlo simulations which has the following advantages: the bias of the resulting empirical level of the test is eliminated, hence the empirical levels can always reach the nominal level, and information about inhomogeneity of the data can be provided.We theoretically justify our testing procedure using Taylor expansions and demonstrate that it is correctly sized through various simulation studies. In our first data application, we discover, in agreement with Illian et al., that Phlebocarya filifolia plants near Perth, Australia, can follow a homogeneous Poisson clustered process that provides insight into the propagation mechanism of these plants. In our second data application, we find, in contrast to Diggle, that a pairwise interaction model provides a good fit to the micro-anatomy data of amacrine cells designed for analyzing the developmental growth of immature retina cells in rabbits. This article has supplementary material online. © 2013 American Statistical Association, Institute of Mathematical Statistics, and Interface Foundation of North America.

  7. Complementizer Agreement in Modern Varieties of West Germanic: A Model of Reanalysis and Renewal

    Science.gov (United States)

    Bousquette, Joshua

    2013-01-01

    This dissertation provides a comparative analysis of Complementizer Agreement (C-agr) in modern dialects of West Germanic from a diachronic perspective, attributing the rise and development of C-agr to the initiation and progression of a Linguistic Cycle specific to C-agr. Approached as a historical process of reanalysis and compensatory renewal…

  8. How Good Can We Get? Using mathematical models to predict the future of athletics

    CERN Document Server

    Mureika, J R

    1998-01-01

    Track and field world records have risen and fallen throughout the history of the sport. A recent rash of record-breaking performances has prompted the question: "How good can we get?". This article offers a review of several attempts to answer this question, based on mathematical modeling of key physiological processes. The predictions are compared with present-day world records, and a discussion of the future of athletics ensues...

  9. New methods to measure and model logistics and goods effects by the use of the CLG-DSS Model

    DEFF Research Database (Denmark)

    Salling, Kim Bang; Jensen, Anders Vestergaard

    2004-01-01

    This paper concerns the assessment and modelling of so-called logistics and goods effects (LG-effects) as part of a wider economic analysis by use of the developed CLG-DSS model. The results presented are based an on-going study, Task 9 about evaluation modelling and decision support systems (DSS......) in the Centre for Logistics and Goods Transport (CLG) 2001-2005 funded by the Danish Council for Technical-Scientific Research (STVF). Within the area of research on logistics the interaction between logistics and transportation is of great relevance. Task 9 and other recent studies have found that several...... companies are taking account of logistics and transport by setting up, among other things, specific departments to improve their handling. Some aspects in the transport sector concerning goods movement and consequences have not so far got the attention they deserve. In CLG Task 9 four LG-effects have been...

  10. Retail Location Choice with Complementary Goods: An Agent-Based Model

    Science.gov (United States)

    Huang, Arthur; Levinson, David

    This paper models the emergence of retail clusters on a supply chain network comprised of suppliers, retailers, and consumers. Firstly, an agent-based model is proposed to investigate retail location distribution in a market of two complementary goods. The methodology controls for supplier locales and unit sales prices of retailers and suppliers, and a consumer’s willingness to patronize a retailer depends on the total travel distance of buying both goods. On a circle comprised of discrete locations, retailers play a non-cooperative game of location choice to maximize individual profits. Our findings suggest that the probability distribution of the number of clusters in equilibrium follows power law and that hierarchical distribution patterns are much more likely to occur than the spread-out ones. In addition, retailers of complementary goods tend to co-locate at supplier locales. Sensitivity tests on the number of retailers are also performed. Secondly, based on the County Business Patterns (CBP) data of Minneapolis-St. Paul from US Census 2000 database, we find that the number of clothing stores and the distribution of food stores at the zip code level follows power-law distribution.

  11. Good initialization model with constrained body structure for scene text recognition

    Science.gov (United States)

    Zhu, Anna; Wang, Guoyou; Dong, Yangbo

    2016-09-01

    Scene text recognition has gained significant attention in the computer vision community. Character detection and recognition are the promise of text recognition and affect the overall performance to a large extent. We proposed a good initialization model for scene character recognition from cropped text regions. We use constrained character's body structures with deformable part-based models to detect and recognize characters in various backgrounds. The character's body structures are achieved by an unsupervised discriminative clustering approach followed by a statistical model and a self-build minimum spanning tree model. Our method utilizes part appearance and location information, and combines character detection and recognition in cropped text region together. The evaluation results on the benchmark datasets demonstrate that our proposed scheme outperforms the state-of-the-art methods both on scene character recognition and word recognition aspects.

  12. Good manufacturing practice for modelling air pollution: Quality criteria for computer models to calculate air pollution

    Science.gov (United States)

    Dekker, C. M.; Sliggers, C. J.

    To spur on quality assurance for models that calculate air pollution, quality criteria for such models have been formulated. By satisfying these criteria the developers of these models and producers of the software packages in this field can assure and account for the quality of their products. In this way critics and users of such (computer) models can gain a clear understanding of the quality of the model. Quality criteria have been formulated for the development of mathematical models, for their programming—including user-friendliness, and for the after-sales service, which is part of the distribution of such software packages. The criteria have been introduced into national and international frameworks to obtain standardization.

  13. Good teacher, good tutor

    Directory of Open Access Journals (Sweden)

    Couto LB

    2016-07-01

    Full Text Available Lucélio B Couto, Gustavo S Romão, Reinaldo B Bestetti  Department of Medicine, University of Ribeirão Preto, Ribeirão Preto, Brazil We have read with great interest the paper by Kassab et al, who have essentially shown that good teachers will be good tutors in a problem-based learning (PBL environment. We have been facing great difficulties to select tutors because there has been no tradition in PBL in our region in the preuniversity teaching. Furthermore, the majority of our teachers have been formed in a discipline-based medical curriculum. Therefore, it is reassuring to learn from the work by Kassab et al that subject-matter mastery is the powerful independent predictor of tutoring skills.  View the original paper by Kassab and colleagues.

  14. A goodness-of-fit test for occupancy models with correlated within-season revisits

    Science.gov (United States)

    Wright, Wilson; Irvine, Kathryn M.; Rodhouse, Thomas J.

    2016-01-01

    Occupancy modeling is important for exploring species distribution patterns and for conservation monitoring. Within this framework, explicit attention is given to species detection probabilities estimated from replicate surveys to sample units. A central assumption is that replicate surveys are independent Bernoulli trials, but this assumption becomes untenable when ecologists serially deploy remote cameras and acoustic recording devices over days and weeks to survey rare and elusive animals. Proposed solutions involve modifying the detection-level component of the model (e.g., first-order Markov covariate). Evaluating whether a model sufficiently accounts for correlation is imperative, but clear guidance for practitioners is lacking. Currently, an omnibus goodnessof- fit test using a chi-square discrepancy measure on unique detection histories is available for occupancy models (MacKenzie and Bailey, Journal of Agricultural, Biological, and Environmental Statistics, 9, 2004, 300; hereafter, MacKenzie– Bailey test). We propose a join count summary measure adapted from spatial statistics to directly assess correlation after fitting a model. We motivate our work with a dataset of multinight bat call recordings from a pilot study for the North American Bat Monitoring Program. We found in simulations that our join count test was more reliable than the MacKenzie–Bailey test for detecting inadequacy of a model that assumed independence, particularly when serial correlation was low to moderate. A model that included a Markov-structured detection-level covariate produced unbiased occupancy estimates except in the presence of strong serial correlation and a revisit design consisting only of temporal replicates. When applied to two common bat species, our approach illustrates that sophisticated models do not guarantee adequate fit to real data, underscoring the importance of model assessment. Our join count test provides a widely applicable goodness-of-fit test and

  15. An Evolutionary Model of Cooperation, Fairness and Altruistic Punishment in Public Good Games

    Science.gov (United States)

    Hetzer, Moritz; Sornette, Didier

    2013-01-01

    We identify and explain the mechanisms that account for the emergence of fairness preferences and altruistic punishment in voluntary contribution mechanisms by combining an evolutionary perspective together with an expected utility model. We aim at filling a gap between the literature on the theory of evolution applied to cooperation and punishment, and the empirical findings from experimental economics. The approach is motivated by previous findings on other-regarding behavior, the co-evolution of culture, genes and social norms, as well as bounded rationality. Our first result reveals the emergence of two distinct evolutionary regimes that force agents to converge either to a defection state or to a state of coordination, depending on the predominant set of self- or other-regarding preferences. Our second result indicates that subjects in laboratory experiments of public goods games with punishment coordinate and punish defectors as a result of an aversion against disadvantageous inequitable outcomes. Our third finding identifies disadvantageous inequity aversion as evolutionary dominant and stable in a heterogeneous population of agents endowed initially only with purely self-regarding preferences. We validate our model using previously obtained results from three independently conducted experiments of public goods games with punishment. PMID:24260101

  16. Canine cell line, IPC-366, as a good model for the study of inflammatory breast cancer.

    Science.gov (United States)

    Caceres, S; Peña, L; Lacerda, L; Illera, M J; de Andres, P J; Larson, R A; Gao, H; Debeb, B G; Woodward, W A; Reuben, J M; Illera, J C

    2017-09-01

    Inflammatory breast cancer (IBC) is an aggressive type of cancer with poor survival in women. Inflammatory mammary cancer (IMC) in dogs is very similar to human IBC and it has been proposed as a good surrogate model for study the human disease. The aim was to determine if IPC-366 shared characteristics with the IBC cell line SUM149. The comparison was conducted in terms of ability to grow (adherent and nonadherent conditions), stem cell markers expression using flow cytometry, protein production using western blot and tumorigenic capacity. Our results revealed that both are capable of forming long-term mammospheres with a grape-like morphology. Adherent and nonadherent cultures exhibited fast growth in vivo. Stem cell markers expressions showed that IPC-366 and SUM149 in adherent and nonadherent conditions has mesenchymal-like characteristics, E-cadherin and N-cadherin, was higher in adherent than in nonadherent cultures. Therefore, this study determines that both cell lines are similar and IPC-366 is a good model for the human and canine disease. © 2016 John Wiley & Sons Ltd.

  17. An evolutionary model of cooperation, fairness and altruistic punishment in public good games.

    Directory of Open Access Journals (Sweden)

    Moritz Hetzer

    Full Text Available We identify and explain the mechanisms that account for the emergence of fairness preferences and altruistic punishment in voluntary contribution mechanisms by combining an evolutionary perspective together with an expected utility model. We aim at filling a gap between the literature on the theory of evolution applied to cooperation and punishment, and the empirical findings from experimental economics. The approach is motivated by previous findings on other-regarding behavior, the co-evolution of culture, genes and social norms, as well as bounded rationality. Our first result reveals the emergence of two distinct evolutionary regimes that force agents to converge either to a defection state or to a state of coordination, depending on the predominant set of self- or other-regarding preferences. Our second result indicates that subjects in laboratory experiments of public goods games with punishment coordinate and punish defectors as a result of an aversion against disadvantageous inequitable outcomes. Our third finding identifies disadvantageous inequity aversion as evolutionary dominant and stable in a heterogeneous population of agents endowed initially only with purely self-regarding preferences. We validate our model using previously obtained results from three independently conducted experiments of public goods games with punishment.

  18. Assessing a brand equity model for fast moving consumer goods in cosmetic and hygiene industry

    Directory of Open Access Journals (Sweden)

    Alireza Karbasivar

    2014-11-01

    Full Text Available This paper presents an empirical investigation to study the effects of ten factors on brand equity. The study provides an assessment using a brand equity model for fast moving consumer goods in cosmetic and hygiene industry. The study has accomplished among people who purchase goods in six major cities of Iran based on an adapted questionnaire originally developed by Aaker (1992a [Aaker, D. A. (1992a. The value of brand equity. Journal of Business Strategy, 13(4, 27-32.]. Cronbach alpha has been calculated as 0.88, which is well above the minimum acceptable level of 0.7. In addition, Kaiser-Meyer-Olkin Measure of Sampling adequacy and Bartlett's test of Sphericity approximation Chi-Square are 0.878, 276628 with Sig. = 0.000, respectively. The proposed study of this paper uses structural equation modeling to test different hypotheses of the survey. The Root Mean Square Error of Approximation (RMSEA, Comparative Fit Index (CFI and Chi-Square/df are 0.067, 0.840 and 4.244 and they are within desirable levels. While the effects of seven factors on brand equity have been confirmed. However, the survey does not confirm the effects of perceived value, advertisement effectiveness and advertisement to brand on brand equity. In our survey, brand loyalty maintains the highest positive impact followed by having updated brand, trust to brand, perceived quality to brand, brand awareness, intensity of supply and perception to brand.

  19. Power and Contention Control Scheme: As a Good Candidate for Interference Modeling in Cognitive Radio Network

    Directory of Open Access Journals (Sweden)

    Ireyuwa E. Igbinosa

    2015-10-01

    Full Text Available Due to the ever growing need for spectrum, the cognitive radio (CR has been proposed to improve the radio spectrum utilization. In this scenario, the secondary users (SU are permitted to share spectrum with the licensed primary users (SU with a strict condition that they do not cause harmful interference to the cognitive network. In this work, we have proposed an interference model for cognitive radio network that utilizes power or contention control interference management schemes. We derived the probability density function (PDF with the power control scheme, where the power of transmission of the CR transmitter is guided by the power control law and also with contention control scheme that has a fixed transmission power for all CR transmitter controlled by a contention control protocol. This protocol makes a decision on which CR transmitter can transmit at any point in time. In this work, we have shown that power and contention control schemes are good candidates for interference modeling in cognitive radio system. The impact of the unknown location of the primary receiver on the resulting interference generated by the CR transmitters was investigated and the results shows that the challenges of the hidden primary receivers lead to higher CR-primary interference in respect to higher mean and variance. Finally, the presented results show power control and the contention control scheme are good candidates in reducing the interference generated by the cognitive radio network.

  20. Coupled Oscillator Model of the Business Cycle withFluctuating Goods Markets

    Science.gov (United States)

    Ikeda, Y.; Aoyama, H.; Fujiwara, Y.; Iyetomi, H.; Ogimoto, K.; Souma, W.; Yoshikawa, H.

    The sectoral synchronization observed for the Japanese business cycle in the Indices of Industrial Production data is an example of synchronization. The stability of this synchronization under a shock, e.g., fluctuation of supply or demand, is a matter of interest in physics and economics. We consider an economic system made up of industry sectors and goods markets in order to analyze the sectoral synchronization observed for the Japanese business cycle. A coupled oscillator model that exhibits synchronization is developed based on the Kuramoto model with inertia by adding goods markets, and analytic solutions of the stationary state and the coupling strength are obtained. We simulate the effects on synchronization of a sectoral shock for systems with different price elasticities and the coupling strengths. Synchronization is reproduced as an equilibrium solution in a nearest neighbor graph. Analysis of the order parameters shows that the synchronization is stable for a finite elasticity, whereas the synchronization is broken and the oscillators behave like a giant oscillator with a certain frequency additional to the common frequency for zero elasticity.

  1. Scientific Opinion on good modelling practice in the context of mechanistic effect models for risk assessment of plant protection products

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Plant Protection Products and their Residues (PPR

    2014-03-01

    Full Text Available The Panel has interpreted the Terms of Reference as a stepwise analysis of issues relevant to both the development and the evaluation of models to assess ecological effects of pesticides. The regulatory model should be selected or developed to address the relevant specific protection goal. The basis of good modelling practice must be the knowledge of relevant processes and the availability of data of sufficient quality. The opinion identifies several critical steps in order to set models within risk assessment, namely: problem formulation, considering the specific protection goals for the taxa or functional groups of concern; model domain of applicability, which drives the species and scenarios to model; species (and life stage selection, considering relevant life history traits and toxicological/toxicokinetics characteristics of the pesticide; selection of the environmental scenario, which is defined by a combination of abiotic, biotic and agronomic parameters to provide a realistic worst-case situation. Model development should follow the modelling cycle, in which every step has to be fully documented: (i problem definition; (ii model formulation, i.e. design of a conceptual model; (iii model formalisation, in which variables and parameters are linked together into mathematical equations or algorithms; (iv model implementation, in which a computer code is produced and verified; (v model setup, including sensitivity analysis, uncertainty analysis and comparison with observed data, that delivers the regulatory model; (vi prior to actual use in risk assessment, the regulatory model should be evaluated for relevance to the specific protection goals; (vii feedback from risk assessor with possible recommendations for model improvement. Model evaluation by regulatory authorities should consider each step of the modelling cycle: the opinion identifies points of particular attention for the use of mechanistic effect models in pesticide risk assessment

  2. The power of a good idea: quantitative modeling of the spread of ideas from epidemiological models

    CERN Document Server

    Bettencourt, L M A; Kaiser, D I; Castillo-Chavez, C; Bettencourt, Lu\\'{i}s M.A.; Cintr\\'{o}n-Arias, Ariel; Kaiser, David I.; Castillo-Ch\\'{a}vez, Carlos

    2005-01-01

    The population dynamics underlying the diffusion of ideas hold many qualitative similarities to those involved in the spread of infections. In spite of much suggestive evidence this analogy is hardly ever quantified in useful ways. The standard benefit of modeling epidemics is the ability to estimate quantitatively population average parameters, such as interpersonal contact rates, incubation times, duration of infectious periods, etc. In most cases such quantities generalize naturally to the spread of ideas and provide a simple means of quantifying sociological and behavioral patterns. Here we apply several paradigmatic models of epidemics to empirical data on the advent and spread of Feynman diagrams through the theoretical physics communities of the USA, Japan, and the USSR in the period immediately after World War II. This test case has the advantage of having been studied historically in great detail, which allows validation of our results. We estimate the effectiveness of adoption of the idea in the thr...

  3. How Bad/Good Are the External Forward Shock Models of Gamma-Ray Bursts?

    CERN Document Server

    Wang, Xiang-Gao; Liang, En-Wei; Gao, He; Li, Liang; Deng, Can-Min; Qin, Song-Mei; Tang, Qing-Wen; Kann, D Alexander; Ryde, Felix; Kumar, Pawan

    2015-01-01

    The external forward shock (EFS) models have been the standard paradigm to interpret the broad-band afterglow data of gamma-ray bursts (GRBs). One prediction of the models is that some afterglow temporal breaks at different energy bands should be achromatic. Observations in the Swift era have revealed chromatic afterglow behaviors at least in some GRBs, casting doubts on the EFS origin of GRB afterglows. In this paper, we perform a systematic study to address the question: how bad/good are the external forward shock models? Our sample includes 85 GRBs well-monitored X-ray and optical lightcurves. Based on how well the data abide by the EFS models, we categorize them as: Gold sample: (Grade I and II) include 45/85 GRBs. They show evidence of, or are consistent with having, an achromatic break. The temporal/spectral behaviors in each afterglow segment are consistent with the predictions (closure relations) of the EFS models. Silver sample: (Grade III and IV) include 37/85 GRBs. They are also consistent with hav...

  4. Lack of agreement for defining 'clinical suspicion of rejection' in liver transplantation: a model to select candidates for liver biopsy.

    Science.gov (United States)

    Rodríguez-Perálvarez, Manuel; García-Caparrós, Carmen; Tsochatzis, Emmanuel; Germani, Giacomo; Hogan, Brian; Poyato-González, Antonio; O'Beirne, James; Senzolo, Marco; Guerrero-Misas, Marta; Montero-Álvarez, Jose L; Patch, David; Barrera, Pilar; Briceño, Javier; Dhillon, Amar P; Burra, Patrizia; Burroughs, Andrew K; De la Mata, Manuel

    2015-04-01

    The gold standard to diagnose acute cellular rejection (ACR) after liver transplantation (LT) is histological evaluation, but there is no consensus to select patients for liver biopsy. We aimed to evaluate the agreement among clinicians to select candidates for liver biopsy early after LT. From a protocol biopsy population (n = 690), we randomly selected 100 LT patients in whom the biopsy was taken 7-10 days after LT. The clinical information between LT and protocol biopsy was given to nine clinicians from three transplant centres who decided whether a liver biopsy was needed. The agreement among clinicians to select candidates for liver biopsy was poor: κ = 0.06-0.62, being κ liver biopsy and moderate-severe ACR in the protocol biopsy was κ liver biopsy is very poor. If further validated the proposed model would provide an objective method to select candidates for liver biopsy after LT.

  5. Kappa as a Parameter of a Symmetry Model for Rater Agreement.

    Science.gov (United States)

    Schuster, Christof

    2001-01-01

    If two raters assign targets to categories, the ratings can be arranged in a two-dimensional contingency table. This article presents a model for the frequencies in such a contingency table for which Cohen's kappa is a parameter. Illustrates the model using data from a study of the psychobiology of depression. (Author/SLD)

  6. Goodness-of-fit tests for vector autoregressive models in time series

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    The paper proposes and studies some diagnostic tools for checking the goodness-of-fit of general parametric vector autoregressive models in time series. The resulted tests are asymptotically chi-squared under the null hypothesis and can detect the alternatives converging to the null at a parametric rate. The tests involve weight functions,which provides us with the flexibility to choose scores for enhancing power performance,especially under directional alternatives. When the alternatives are not directional,we construct asymptotically distribution-free maximin tests for a large class of alternatives. A possibility to construct score-based omnibus tests is discussed when the alternative is saturated. The power performance is also investigated. In addition,when the sample size is small,a nonparametric Monte Carlo test approach for dependent data is proposed to improve the performance of the tests. The algorithm is easy to implement. Simulation studies and real applications are carried out for illustration.

  7. Identification of Amino Acid Sequences with Good Folding Properties in an Off-Lattice Model

    CERN Document Server

    Irbäck, Anders; Potthast, Frank

    2008-01-01

    Folding properties of a two-dimensional toy protein model containing only two amino-acid types, hydrophobic and hydrophilic, respectively, are analyzed. An efficient Monte Carlo procedure is employed to ensure that the ground states are found. The thermodynamic properties are found to be strongly sequence dependent in contrast to the kinetic ones. Hence, criteria for good folders are defined entirely in terms of thermodynamic fluctuations. With these criteria sequence patterns that fold well are isolated. For 300 chains with 20 randomly chosen binary residues approximately 10% meet these criteria. Also, an analysis is performed by means of statistical and artificial neural network methods from which it is concluded that the folding properties can be predicted to a certain degree given the binary numbers characterizing the sequences.

  8. How Bad or Good Are the External Forward Shock Afterglow Models of Gamma-Ray Bursts?

    Science.gov (United States)

    Wang, Xiang-Gao; Zhang, Bing; Liang, En-Wei; Gao, He; Li, Liang; Deng, Can-Min; Qin, Song-Mei; Tang, Qing-Wen; Kann, D. Alexander; Ryde, Felix; Kumar, Pawan

    2015-07-01

    The external forward shock models have been the standard paradigm to interpret the broadband afterglow data of gamma-ray bursts (GRBs). One prediction of the models is that some afterglow temporal breaks at different energy bands should be achromatic; that is, the break times should be the same in different frequencies. Multiwavelength observations in the Swift era have revealed chromatic afterglow behaviors at least in some GRBs, casting doubts on the external forward shock origin of GRB afterglows. In this paper, using a large sample of GRBs with both X-ray and optical afterglow data, we perform a systematic study to address the question: how bad or good are the external forward shock models? Our sample includes 85 GRBs up to 2014 March with well-monitored X-ray and optical light curves. Based on how well the data abide by the external forward shock models, we categorize them into five grades and three samples. The first two grades (Grade I and II) include 45 of 85 GRBs. They show evidence of, or are consistent with having, an achromatic break. The temporal and spectral behaviors in each afterglow segment are consistent with the predictions (the “closure relations”) of the forward shock models. These GRBs are included in the Gold sample. The next two grades (Grade III and IV) include 37 of 85 GRBs. They are also consistent with having an achromatic break, even though one or more afterglow segments do not comply with the closure relations. These GRBs are included in the Silver sample. Finally, Grade V (3/85) shows direct evidence of chromatic behaviors, suggesting that the external shock models are inconsistent with the data. These are included in the Bad sample. We further perform statistical analyses of various observational properties (temporal index α, spectral index β, break time tb) and model parameters (energy injection index q, electron spectral index p, jet opening angle {θ }j, radiative efficiency ηγ, and so on) of the GRBs in the Gold sample

  9. Model transparency and validation: a report of the ISPOR-SMDM Modeling Good Research Practices Task Force--7.

    Science.gov (United States)

    Eddy, David M; Hollingworth, William; Caro, J Jaime; Tsevat, Joel; McDonald, Kathryn M; Wong, John B

    2012-01-01

    Trust and confidence are critical to the success of health care models. There are two main methods for achieving this: transparency (people can see how the model is built) and validation (how well the model reproduces reality). This report describes recommendations for achieving transparency and validation developed by a taskforce appointed by the International Society for Pharmacoeconomics and Outcomes Research and the Society for Medical Decision Making. Recommendations were developed iteratively by the authors. A nontechnical description--including model type, intended applications, funding sources, structure, intended uses, inputs, outputs, other components that determine function, and their relationships, data sources, validation methods, results, and limitations--should be made available to anyone. Technical documentation, written in sufficient detail to enable a reader with necessary expertise to evaluate the model and potentially reproduce it, should be made available openly or under agreements that protect intellectual property, at the discretion of the modelers. Validation involves face validity (wherein experts evaluate model structure, data sources, assumptions, and results), verification or internal validity (check accuracy of coding), cross validity (comparison of results with other models analyzing the same problem), external validity (comparing model results with real-world results), and predictive validity (comparing model results with prospectively observed events). The last two are the strongest form of validation. Each section of this article contains a number of recommendations that were iterated among the authors, as well as among the wider modeling taskforce, jointly set up by the International Society for Pharmacoeconomics and Outcomes Research and the Society for Medical Decision Making.

  10. Goodness of fit to a mathematical model for Drosophila sleep behavior is reduced in hyposomnolent mutants

    Directory of Open Access Journals (Sweden)

    Joshua M. Diamond

    2016-01-01

    Full Text Available The conserved nature of sleep in Drosophila has allowed the fruit fly to emerge in the last decade as a powerful model organism in which to study sleep. Recent sleep studies in Drosophila have focused on the discovery and characterization of hyposomnolent mutants. One common feature of these animals is a change in sleep architecture: sleep bout count tends to be greater, and sleep bout length lower, in hyposomnolent mutants. I propose a mathematical model, produced by least-squares nonlinear regression to fit the form Y = aX∧b, which can explain sleep behavior in the healthy animal as well as previously-reported changes in total sleep and sleep architecture in hyposomnolent mutants. This model, fit to sleep data, yields coefficient of determination R squared, which describes goodness of fit. R squared is lower, as compared to control, in hyposomnolent mutants insomniac and fumin. My findings raise the possibility that low R squared is a feature of all hyposomnolent mutants, not just insomniac and fumin. If this were the case, R squared could emerge as a novel means by which sleep researchers might assess sleep dysfunction.

  11. Safety assessment of dangerous goods transport enterprise based on the relative entropy aggregation in group decision making model.

    Science.gov (United States)

    Wu, Jun; Li, Chengbing; Huo, Yueying

    2014-01-01

    Safety of dangerous goods transport is directly related to the operation safety of dangerous goods transport enterprise. Aiming at the problem of the high accident rate and large harm in dangerous goods logistics transportation, this paper took the group decision making problem based on integration and coordination thought into a multiagent multiobjective group decision making problem; a secondary decision model was established and applied to the safety assessment of dangerous goods transport enterprise. First of all, we used dynamic multivalue background and entropy theory building the first level multiobjective decision model. Secondly, experts were to empower according to the principle of clustering analysis, and combining with the relative entropy theory to establish a secondary rally optimization model based on relative entropy in group decision making, and discuss the solution of the model. Then, after investigation and analysis, we establish the dangerous goods transport enterprise safety evaluation index system. Finally, case analysis to five dangerous goods transport enterprises in the Inner Mongolia Autonomous Region validates the feasibility and effectiveness of this model for dangerous goods transport enterprise recognition, which provides vital decision making basis for recognizing the dangerous goods transport enterprises.

  12. Agreement technologies

    CERN Document Server

    Ossowski, Sascha

    2013-01-01

    More and more transactions, whether in business or related to leisure activities, are mediated automatically by computers and computer networks, and this trend is having a significant impact on the conception and design of new computer applications. The next generation of these applications will be based on software agents to which increasingly complex tasks can be delegated, and which interact with each other in sophisticated ways so as to forge agreements in the interest of their human users. The wide variety of technologies supporting this vision is the subject of this volume. It summarises

  13. Comparing the Goodness of Different Statistical Criteria for Evaluating the Soil Water Infiltration Models

    Directory of Open Access Journals (Sweden)

    S. Mirzaee

    2016-02-01

    Full Text Available Introduction: The infiltration process is one of the most important components of the hydrologic cycle. Quantifying the infiltration water into soil is of great importance in watershed management. Prediction of flooding, erosion and pollutant transport all depends on the rate of runoff which is directly affected by the rate of infiltration. Quantification of infiltration water into soil is also necessary to determine the availability of water for crop growth and to estimate the amount of additional water needed for irrigation. Thus, an accurate model is required to estimate infiltration of water into soil. The ability of physical and empirical models in simulation of soil processes is commonly measured through comparisons of simulated and observed values. For these reasons, a large variety of indices have been proposed and used over the years in comparison of infiltration water into soil models. Among the proposed indices, some are absolute criteria such as the widely used root mean square error (RMSE, while others are relative criteria (i.e. normalized such as the Nash and Sutcliffe (1970 efficiency criterion (NSE. Selecting and using appropriate statistical criteria to evaluate and interpretation of the results for infiltration water into soil models is essential because each of the used criteria focus on specific types of errors. Also, descriptions of various goodness of fit indices or indicators including their advantages and shortcomings, and rigorous discussions on the suitability of each index are very important. The objective of this study is to compare the goodness of different statistical criteria to evaluate infiltration of water into soil models. Comparison techniques were considered to define the best models: coefficient of determination (R2, root mean square error (RMSE, efficiency criteria (NSEI and modified forms (such as NSEjI, NSESQRTI, NSElnI and NSEiI. Comparatively little work has been carried out on the meaning and

  14. Model transparency and validation: a report of the ISPOR-SMDM Modeling Good Research Practices Task Force-7.

    Science.gov (United States)

    Eddy, David M; Hollingworth, William; Caro, J Jaime; Tsevat, Joel; McDonald, Kathryn M; Wong, John B

    2012-01-01

    Trust and confidence are critical to the success of health care models. There are two main methods for achieving this: transparency (people can see how the model is built) and validation (how well it reproduces reality). This report describes recommendations for achieving transparency and validation, developed by a task force appointed by the International Society for Pharmacoeconomics and Outcomes Research (ISPOR) and the Society for Medical Decision Making (SMDM). Recommendations were developed iteratively by the authors. A nontechnical description should be made available to anyone-including model type and intended applications; funding sources; structure; inputs, outputs, other components that determine function, and their relationships; data sources; validation methods and results; and limitations. Technical documentation, written in sufficient detail to enable a reader with necessary expertise to evaluate the model and potentially reproduce it, should be made available openly or under agreements that protect intellectual property, at the discretion of the modelers. Validation involves face validity (wherein experts evaluate model structure, data sources, assumptions, and results), verification or internal validity (check accuracy of coding), cross validity (comparison of results with other models analyzing same problem), external validity (comparing model results to real-world results), and predictive validity (comparing model results with prospectively observed events). The last two are the strongest form of validation. Each section of this paper contains a number of recommendations that were iterated among the authors, as well as the wider modeling task force jointly set up by the International Society for Pharmacoeconomics and Outcomes Research and the Society for Medical Decision Making.

  15. Spatial and temporal agreement in climate model simulations of the Interdecadal Pacific Oscillation

    Science.gov (United States)

    Henley, Benjamin J.; Meehl, Gerald; Power, Scott B.; Folland, Chris K.; King, Andrew D.; Brown, Jaclyn N.; Karoly, David J.; Delage, Francois; E Gallant, Ailie J.; Freund, Mandy; Neukom, Raphael

    2017-04-01

    Accelerated warming and hiatus periods in the long-term rise of Global Mean Surface Temperature (GMST) have, in recent decades, been associated with the Interdecadal Pacific Oscillation (IPO). Critically, decadal climate prediction relies on the skill of state-of-the-art climate models to reliably represent these low-frequency climate variations. We undertake a systematic evaluation of the simulation of the IPO in the suite of Coupled Model Intercomparison Project 5 (CMIP5) models. We track the IPO in pre-industrial (control) and all-forcings (historical) experiments using the IPO tripole index (TPI). The TPI is explicitly aligned with the observed spatial pattern of the IPO, and circumvents assumptions about the nature of global warming. We find that many models underestimate the ratio of decadal-to-total variance in sea surface temperatures (SSTs). However, the basin-wide spatial pattern of positive and negative phases of the IPO are simulated reasonably well, with spatial pattern correlation coefficients between observations and models spanning the range 0.4-0.8. Deficiencies are mainly in the extratropical Pacific. Models that better capture the spatial pattern of the IPO also tend to more realistically simulate the ratio of decadal to total variance. Of the 13% of model centuries that have a fractional bias in the decadal-to-total TPI variance of 0.2 or less, 84% also have a spatial pattern correlation coefficient with the observed pattern exceeding 0.5. This result is highly consistent across both IPO positive and negative phases. This is evidence that the IPO is related to one or more inherent dynamical mechanisms of the climate system.

  16. Agreement of land use regression models with personal exposure measurements of particulate matter and nitrogen oxides air pollution.

    Science.gov (United States)

    Montagne, Denise; Hoek, Gerard; Nieuwenhuijsen, Mark; Lanki, Timo; Pennanen, Arto; Portella, Meritxell; Meliefste, Kees; Eeftens, Marloes; Yli-Tuomi, Tarja; Cirach, Marta; Brunekreef, Bert

    2013-08-06

    Land use regression (LUR) models are often used to predict long-term average concentrations of air pollutants. Little is known how well LUR models predict personal exposure. In this study, the agreement of LUR models with measured personal exposure was assessed. The measured components were particulate matter with a diameter smaller than 2.5 μm (PM2.5), soot (reflectance of PM2.5), nitrogen oxides (NOx), and nitrogen dioxide (NO2). In Helsinki, Utrecht, and Barcelona, 15 volunteers (from semiurban, urban background, and traffic sites) followed prescribed time activity patterns. Per participant, six 96 h outdoor, indoor, and personal measurements spread over three seasons were conducted. Soot LUR models were significantly correlated with measured average outdoor and personal soot concentrations. Soot LUR models explained 39%, 44%, and 20% of personal exposure variability (R(2)) in Helsinki, Utrecht, and Barcelona. NO2 LUR models significantly predicted outdoor concentrations and personal exposure in Utrecht and Helsinki, whereas NOx and PM2.5 LUR models did not predict personal exposure. PM2.5, NO2, and NOx models were correlated with personal soot, the component least affected by indoor sources. LUR modeled and measured outdoor, indoor, and personal concentrations were highly correlated for all pollutants when data from the three cities were combined. This study supports the use of intraurban LUR models for especially soot in air pollution epidemiology.

  17. Towards an Extended Evolutionary Game Theory with Survival Analysis and Agreement Algorithms for Modeling Uncertainty, Vulnerability, and Deception

    Science.gov (United States)

    Ma, Zhanshan (Sam)

    Competition, cooperation and communication are the three fundamental relationships upon which natural selection acts in the evolution of life. Evolutionary game theory (EGT) is a 'marriage' between game theory and Darwin's evolution theory; it gains additional modeling power and flexibility by adopting population dynamics theory. In EGT, natural selection acts as optimization agents and produces inherent strategies, which eliminates some essential assumptions in traditional game theory such as rationality and allows more realistic modeling of many problems. Prisoner's Dilemma (PD) and Sir Philip Sidney (SPS) games are two well-known examples of EGT, which are formulated to study cooperation and communication, respectively. Despite its huge success, EGT exposes a certain degree of weakness in dealing with time-, space- and covariate-dependent (i.e., dynamic) uncertainty, vulnerability and deception. In this paper, I propose to extend EGT in two ways to overcome the weakness. First, I introduce survival analysis modeling to describe the lifetime or fitness of game players. This extension allows more flexible and powerful modeling of the dynamic uncertainty and vulnerability (collectively equivalent to the dynamic frailty in survival analysis). Secondly, I introduce agreement algorithms, which can be the Agreement algorithms in distributed computing (e.g., Byzantine Generals Problem [6][8], Dynamic Hybrid Fault Models [12]) or any algorithms that set and enforce the rules for players to determine their consensus. The second extension is particularly useful for modeling dynamic deception (e.g., asymmetric faults in fault tolerance and deception in animal communication). From a computational perspective, the extended evolutionary game theory (EEGT) modeling, when implemented in simulation, is equivalent to an optimization methodology that is similar to evolutionary computing approaches such as Genetic algorithms with dynamic populations [15][17].

  18. Summary goodness-of-fit statistics for binary generalized linear models with noncanonical link functions.

    Science.gov (United States)

    Canary, Jana D; Blizzard, Leigh; Barry, Ronald P; Hosmer, David W; Quinn, Stephen J

    2016-05-01

    Generalized linear models (GLM) with a canonical logit link function are the primary modeling technique used to relate a binary outcome to predictor variables. However, noncanonical links can offer more flexibility, producing convenient analytical quantities (e.g., probit GLMs in toxicology) and desired measures of effect (e.g., relative risk from log GLMs). Many summary goodness-of-fit (GOF) statistics exist for logistic GLM. Their properties make the development of GOF statistics relatively straightforward, but it can be more difficult under noncanonical links. Although GOF tests for logistic GLM with continuous covariates (GLMCC) have been applied to GLMCCs with log links, we know of no GOF tests in the literature specifically developed for GLMCCs that can be applied regardless of link function chosen. We generalize the Tsiatis GOF statistic originally developed for logistic GLMCCs, (TG), so that it can be applied under any link function. Further, we show that the algebraically related Hosmer-Lemeshow (HL) and Pigeon-Heyse (J(2) ) statistics can be applied directly. In a simulation study, TG, HL, and J(2) were used to evaluate the fit of probit, log-log, complementary log-log, and log models, all calculated with a common grouping method. The TG statistic consistently maintained Type I error rates, while those of HL and J(2) were often lower than expected if terms with little influence were included. Generally, the statistics had similar power to detect an incorrect model. An exception occurred when a log GLMCC was incorrectly fit to data generated from a logistic GLMCC. In this case, TG had more power than HL or J(2) .

  19. A good resuscitation model of non-transthoracic cardiopulmonary bypass in rats

    Institute of Scientific and Technical Information of China (English)

    AN Yong; XIAO Ying-bin; ZHONG Qian-jin

    2007-01-01

    Objective:To establish a good recoverable rat model of cardiopulmonary bypass (CPB) to lay the foundation for studying the pathophysiology of CPB.Methods:Twenty adult male Sprague-Dawley rats weighing 480 g um via the right jugular vein and further transferred by a miniaturized roller pump to a hollow fiber oxgenator and back to the rat via the left carotid artery. Priming consisted of 8 ml of homologous blood and 6 ml of colloid. The surface of the hollow fiber oxgenator was 0.075 m2. Rats were catheterized and brought in bypass for 120 min at a flow rate of 100-120 ml/kg/min. Oxygen flow/ perfusion flow was 0. 8 to 1. 0, the mean arterial pressure (MAP) kept in 60-80 mmHg. Blood gas analysis, lactate dehydrogenase (LDH), and survival rate were examined subsequently.Results: All CPB rats recovered from the operative process without incident and remained uneventful within one week. Normal cardiac function after successful weaning was confirmed by electrocardiography and blood pressure measurements. MAP remained stable. The results of blood gas analysis at different time points were within a normal range. No significant haemolysis could be detected in the given time frame under bypass condition by using LDH.Conclusions: The rat model of CPB can principally simulate the clinical setting of human CPB. The nontransthoracic model is easy to establish and is associated with excellent recovery. This well reproducible model may open the field for various studies on pathophysiological process of CPB and also of systemic ischemia-reperfusion injury in vivo.

  20. The Sicomines Agreement

    DEFF Research Database (Denmark)

    Jansson, Johanna

    ), was to the benefit of the policy preferences of the IMF and the World Bank. This case thus indicates that since China’s own aspirations are changeable, its emergence as an alternative development partner may not bring about any substantive change of direction for the DRC’s international relations. Furthermore......, the investment into the DRC’s mining sector is in itself beneficial for the country, and the renegotiation of the agreement was positive in the sense that the Congolese state guarantee for the mining component was removed. However, the question of whether the Sicomines agreement is a good deal for the DRC...

  1. A theoretical framework of good health status of Jamaicans: using econometric analysis to model good health status over the life course

    Directory of Open Access Journals (Sweden)

    Paul A Bourne

    2009-07-01

    Full Text Available Background: In recent times, the World Health Organization has increasing drawn attention to the pivotal role of social conditions in determining health status. The non-biological factors produced inequalities in health and need to be considered in health development. In spite of this, extensive review of health Caribbean revealed that no study has examined health status over the life course of Jamaicans. With the value of research in public health, this study is timely and will add value to understand the elderly, middle age and young adults in Jamaica. Objective: The aim of this study is to develop models that can be used to examine (or evaluate health of Jamaicans, elderly, middle age and young adults. Method: The current study used data from a cross-sectional survey which was conducted between July and October 2002. Stratified random probability sampling technique was used to collect the data from 25,018 respondents across the island. The non-response rate for the survey was 29.7% with 20.5% who did not respond to particular questions, 9.0% did not participated in the survey and another 0.2% was rejected due to data cleaning. Logistic regression analyses were used to model health status of Jamaicans, young adults, middle age adults and elderly. The predictive power of the model was tested using Omnibus Test of Model and Hosmer and Lemeshow (24 was used to examine goodness of fit of the model. The correlation matrix was examined in order to ascertain whether autocorrelation (or multi-collinearity existed between variables. Results: Using logistic regression analysis, eleven variables emerged as statistically significant predictors of current good health Status of Jamaicans (p<0.05. The factors are retirement income (95%CI=0.487-0.958, logged medical expenditure (95% Confidence Interval, CI =0.907-0.993, marital status (Separated or widowed or divorced: 95%CI=0.309-0.464; married: 95%CI=0.495-0.667; Never married, health insurance (95%CI=0

  2. Adjusting eptifibatide doses for renal impairment: a model of dosing agreement among various methods of estimating creatinine clearance.

    Science.gov (United States)

    Healy, Martha F; Speroni, Karen Gabel; Eugenio, Kenneth R; Murphy, Patricia M

    2012-04-01

    Because of the renal elimination and increased risk for bleeding events at supratherapeutic doses of eptifibatide, the manufacturer recommends dosing adjustment in patients with renal dysfunction. Methods commonly used to estimate renal dysfunction in hospital settings may be inconsistent with those studied and recommended by the manufacturer. To compare hypothetical renal dosing adjustments of eptifibatide using both the recommended method and several other commonly used formulas for estimating kidney function. Sex, age, weight, height, serum creatinine, and estimated glomerular filtration rate (eGFR) were obtained retrospectively from the records of patients who received eptifibatide during a 12-month period. Renal dosing decisions were determined for each patient based on creatinine clearance (CrCl) estimates via the Cockcroft-Gault formula (CG) with actual body weight (ABW), ideal body weight (IBW) or adjusted weight (ADJW), and eGFR from the Modification of Diet in Renal Disease formula. Percent agreement and Cohen κ were calculated comparing dosing decisions for each formula to the standard CG-ABW. In this analysis of 179 patients, percent agreement as compared to CG-ABW varied (CG-IBW: 90.50%, CG-ADJW: 95.53%, and eGFR: 93.30%). All κ coefficients were categorized as good. In the 20% of patients receiving an adjusted dose by any of the methods, 68.6% could have received a dose different from that determined using the CG-ABW formula. In the patients with renal impairment (CrCl <50 mL/min) in this study, two thirds would have received an unnecessary 50% dose adjustment discordant from the manufacturer's recommendation. Because failure to adjust eptifibatide doses in patients with renal impairment has led to increased bleeding events, practitioners may be inclined to err on the side of caution. However, studies have shown that suboptimal doses of eptifibatide lead to suboptimal outcomes. Therefore, correct dosing of eptifibatide is important to both patient

  3. On the agreement between small-world-like OFC model and real earthquakes

    Energy Technology Data Exchange (ETDEWEB)

    Ferreira, Douglas S.R., E-mail: douglas.ferreira@ifrj.edu.br [Instituto Federal de Educação, Ciência e Tecnologia do Rio de Janeiro, Paracambi, RJ (Brazil); Geophysics Department, Observatório Nacional, Rio de Janeiro, RJ (Brazil); Papa, Andrés R.R., E-mail: papa@on.br [Geophysics Department, Observatório Nacional, Rio de Janeiro, RJ (Brazil); Instituto de Física, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ (Brazil); Menezes, Ronaldo, E-mail: rmenezes@cs.fit.edu [BioComplex Laboratory, Computer Sciences, Florida Institute of Technology, Melbourne (United States)

    2015-03-20

    In this article we implemented simulations of the OFC model for earthquakes for two different topologies: regular and small-world, where in the latter the links are randomly rewired with probability p. In both topologies, we have studied the distribution of time intervals between consecutive earthquakes and the border effects present in each one. In addition, we also have characterized the influence that the probability p produces in certain characteristics of the lattice and in the intensity of border effects. From the two topologies, networks of consecutive epicenters were constructed, that allowed us to analyze the distribution of connectivities of each one. In our results distributions arise belonging to a family of non-traditional distributions functions, which agrees with previous studies using data from actual earthquakes. Our results reinforce the idea that the Earth is in a critical self-organized state and furthermore point towards temporal and spatial correlations between earthquakes in different places. - Highlights: • OFC model simulations for regular and small-world topologies. • For small-world topology distributions agree remarkably well with actual earthquakes. • Reinforce the idea of a critical self-organized state for the Earth's crust. • Point towards temporal and spatial correlations between far earthquakes in far places.

  4. The Sender-Excited Secret Key Agreement Model: Capacity and Error Exponents

    CERN Document Server

    Chou, Tzu-Han; Draper, Stark C

    2011-01-01

    We consider fundamental limits of the secret key generation problem when the sources are randomly excited by the sender and there is a noiseless public discussion channel. In many practical communication settings, the sources or channels may be influenced by some parties involved. Similar to recent works on probing capacity and channels with action-dependent states, our system model captures such a scenario. We derive single-letter expressions for the secret key capacity. Our coding strategy involves wiretap channel coding and a key generation scheme. We show that the secret key capacity is composed of both source- and channel-type randomness. By assuming that the eavesdropper receives a degraded version of the legitimate receiver's observation, we also obtain a capacity result that does not involve any auxiliary random variables, and thus it is amenable to numerical evaluation. By evaluating the capacity for several degraded channels, we show that there is a fundamental interplay between the portion of the s...

  5. On the agreement between small-world-like OFC model and real earthquakes

    CERN Document Server

    Ferreira, Douglas S R; Menezes, Ronaldo

    2014-01-01

    In this article we implemented simulations of the OFC model for earthquakes for two different topologies: regular and small-world, where in the latter the links are randomly rewired with probability $p$ . In both topologies, we have studied the distribution of time intervals between consecutive earthquakes and the border effects present in each one. In addition, we also have characterized the influence that the probability $p$ produces in certain characteristics of the lattice and in the intensity of border effects. From the two topologies, networks of consecutive epicenters were constructed, that allowed us to analyze the distribution of connectivities of each one. In our results distributions arise belonging to a family of non-traditional distributions functions, which agrees with previous studies using data from actual earthquakes. Our results reinforce the idea that the Earth is in a critical self-organized state and furthermore point towards temporal and spatial correlations between earthquakes in differ...

  6. Lindahl Equilibrium and Schweitzer's Open Club Model Semi-Public Goods

    NARCIS (Netherlands)

    Ten Raa, T.; Gilles, R.P.

    2003-01-01

    Limit core allocations are the ones that remain in the core of a replicated economy.An equivalent notion for economies with public goods is Schweizer s concept of club e ciency under a variable number of economic agents.We extend this notion to economies with goods that have a semi-public nature.We

  7. Assessment model for the transport of dangerous goods through road tunnels

    NARCIS (Netherlands)

    Nelisse, R.M.L.; Vrouwenvelder, A.C.W.M.

    2012-01-01

    In many cases decisions have to be made with respect to the safety level that has to be maintained in tunnels. In this paper the central question is how one can decide between (a) a tunnel with limited allowance for dangerous goods and a deviation route for the prohibited goods or (b) a tunnel

  8. Lindahl Equilibrium and Schweitzer's Open Club Model Semi-Public Goods

    NARCIS (Netherlands)

    Ten Raa, T.; Gilles, R.P.

    2003-01-01

    Limit core allocations are the ones that remain in the core of a replicated economy.An equivalent notion for economies with public goods is Schweizer s concept of club e ciency under a variable number of economic agents.We extend this notion to economies with goods that have a semi-public nature.We

  9. Mental health advocacy and African and Caribbean men: good practice principles and organizational models for delivery.

    Science.gov (United States)

    Newbigging, Karen; McKeown, Mick; French, Beverley

    2013-03-01

    Advocacy has a critical role to play in addressing concerns about access to appropriate mental health care and treatment for African and Caribbean men. To investigate good practice principles and organizational models for mental health advocacy provision for African and Caribbean men. The study consisted of: (i) A systematic literature review. Bibliographic and internet searching was undertaken from 1994 to 2006. The inclusion criteria related to mental health, advocacy provision for African and Caribbean men. (ii) Four focus groups with African and Caribbean men to explore needs for and experiences of mental health advocacy. (iii) An investigation into current advocacy provision through a survey of advocacy provision in England, Wales and Northern Ireland. (iv) Twenty-two qualitative stakeholder interviews to investigate the operation of mental health advocacy for this client group. The study was undertaken in partnership with two service user-led organizations and an African Caribbean mental health service. Primary research in this area is scant. Mainstream mental health advocacy services are often poor at providing appropriate services. Services developed by the Black Community and voluntary sector are grounded in different conceptualizations of advocacy and sharper understanding of the needs of African and Caribbean men. The lack of sustainable funding for these organizations is a major barrier to the development of high-quality advocacy for this group, reflecting a lack of understanding about their distinctive role. The commissioning and provision of mental health advocacy needs to recognize the distinct experiences of African and Caribbean men and develop capacity in the range of organizations to ensure equitable access. © 2011 Blackwell Publishing Ltd.

  10. A simulation-based goodness-of-fit test for random effects in generalized linear mixed models

    DEFF Research Database (Denmark)

    Waagepetersen, Rasmus

    2006-01-01

    The goodness-of-fit of the distribution of random effects in a generalized linear mixed model is assessed using a conditional simulation of the random effects conditional on the observations. Provided that the specified joint model for random effects and observations is correct, the marginal...

  11. A simulation-based goodness-of-fit test for random effects in generalized linear mixed models

    DEFF Research Database (Denmark)

    Waagepetersen, Rasmus Plenge

    The goodness-of-fit of the distribution of random effects in a generalized linear mixed model is assessed using a conditional simulation of the random effects conditional on the observations. Provided that the specified joint model for random effects and observations is correct, the marginal...

  12. Supporting good practice in the provision of services to people with comorbid mental health and alcohol and other drug problems in Australia: describing key elements of good service models

    National Research Council Canada - National Science Library

    Merkes, Monika; Lewis, Virginia; Canaway, Rachel

    2010-01-01

    ... the range of service delivery models is apparent internationally or at the national level. The aims of the current research were to identify and describe elements of good practice in current service models of treatment of comorbidity in Australia...

  13. Is the Linear Modeling Technique Good Enough for Optimal Form Design? A Comparison of Quantitative Analysis Models

    Directory of Open Access Journals (Sweden)

    Yang-Cheng Lin

    2012-01-01

    Full Text Available How to design highly reputable and hot-selling products is an essential issue in product design. Whether consumers choose a product depends largely on their perception of the product image. A consumer-oriented design approach presented in this paper helps product designers incorporate consumers’ perceptions of product forms in the design process. The consumer-oriented design approach uses quantification theory type I, grey prediction (the linear modeling technique, and neural networks (the nonlinear modeling technique to determine the optimal form combination of product design for matching a given product image. An experimental study based on the concept of Kansei Engineering is conducted to collect numerical data for examining the relationship between consumers’ perception of product image and product form elements of personal digital assistants (PDAs. The result of performance comparison shows that the QTTI model is good enough to help product designers determine the optimal form combination of product design. Although the PDA form design is used as a case study, the approach is applicable to other consumer products with various design elements and product images. The approach provides an effective mechanism for facilitating the consumer-oriented product design process.

  14. Is the linear modeling technique good enough for optimal form design? A comparison of quantitative analysis models.

    Science.gov (United States)

    Lin, Yang-Cheng; Yeh, Chung-Hsing; Wang, Chen-Cheng; Wei, Chun-Chun

    2012-01-01

    How to design highly reputable and hot-selling products is an essential issue in product design. Whether consumers choose a product depends largely on their perception of the product image. A consumer-oriented design approach presented in this paper helps product designers incorporate consumers' perceptions of product forms in the design process. The consumer-oriented design approach uses quantification theory type I, grey prediction (the linear modeling technique), and neural networks (the nonlinear modeling technique) to determine the optimal form combination of product design for matching a given product image. An experimental study based on the concept of Kansei Engineering is conducted to collect numerical data for examining the relationship between consumers' perception of product image and product form elements of personal digital assistants (PDAs). The result of performance comparison shows that the QTTI model is good enough to help product designers determine the optimal form combination of product design. Although the PDA form design is used as a case study, the approach is applicable to other consumer products with various design elements and product images. The approach provides an effective mechanism for facilitating the consumer-oriented product design process.

  15. Exploring rater agreement: configurations of agreement and disagreement

    Directory of Open Access Journals (Sweden)

    ALEXANDER VON EYE

    2006-03-01

    Full Text Available At the level of manifest categorical variables, a large number of coefficients and models for the examination of rater agreement has been proposed and used for descriptive and explanatory purposes. This article focuses on exploring rater agreement. Configural Frequency Analysis (CFA is proposed as a method of exploration of cross-classifications of raters’ judgements. CFA allows researchers to (1 examine individual cells and sets of cells in agreement tables; (2 examine cells that indicate disagreement; and (3 explore agreement and disagreement among three or more raters. Four CFA base models are discussed. The first is the model of rater agreement that is also used for Cohen’s (1960  (kappa. This model proposes independence of raters’ judgements. Deviations from this model suggest agreement or disagreement beyond chance. The second CFA model is based on a log-linear null model. This model is also used for Brennan and Prediger’s (1981 n. It proposes a uniform distribution of ratings. The third model is that of Tanner and Young (1985. This model proposes equal weights for agreement cases and independence otherwise. The fourth model is the quasi-independence model. This model allows one to blank out agreement cells and thus to focus solely on patterns of disagreement. Examples use data from applicant selection.

  16. The Shared Supervision Model: "Let's Start at the Very Beginning. A Very Good Place to Start!"

    Science.gov (United States)

    Eberly, Jody L.; Joshi, Arti; Galen, Harlene

    2009-01-01

    Periodic reexamination of existing professional development school forms is good practice to ascertain whether goals are being met. Such an assessment was sparked by a request from a superintendent in a 14-year-old professional development school structure at a public college in the Northeast. This assessment revealed that although the…

  17. Variability in and agreement between modeled and personal continuously measured black carbon levels using novel smartphone and sensor technologies.

    Science.gov (United States)

    Nieuwenhuijsen, Mark J; Donaire-Gonzalez, David; Rivas, Ioar; de Castro, Montserrat; Cirach, Marta; Hoek, Gerard; Seto, Edmund; Jerrett, Michael; Sunyer, Jordi

    2015-03-01

    Novel technologies, such as smartphones and small personal continuous air pollution sensors, can now facilitate better personal estimates of air pollution in relation to location. Such information can provide us with a better understanding about whether and how personal exposures relate to residential air pollution estimates, which are normally used in epidemiological studies. The aims of this study were to examine (1) the variability in personal air pollution levels during the day and (2) the relationship between modeled home and school estimates and continuously measured personal air pollution exposure levels in different microenvironments (e.g., home, school, and commute). We focused on black carbon as an indicator of traffic-related air pollution. We recruited 54 school children (aged 7-11) from 29 different schools around Barcelona as part of the BREATHE study, an epidemiological study of the relation between air pollution and brain development. For 2 typical week days during 2012-2013, the children were given a smartphone with CalFit software to obtain information on their location and physical activity level and a small sensor, the micro-aethalometer model AE51, to measure their black carbon levels simultaneously and continuously. We estimated their home and school exposure to PM2.5 filter absorbance, which is well-correlated with black carbon, using a temporally adjusted PM2.5 absorbance land use regression (LUR) model. We found considerable variation in the black carbon levels during the day, with the highest levels measured during commuting periods (geometric mean = 2.8 μg/m(3)) and the lowest levels at home (geometric mean = 1.3 μg/m(3)). Hourly temporally adjusted LUR model estimates for the home and school showed moderate to good correlation with measured personal black carbon levels at home and school (r = 0.59 and 0.68, respectively) and lower correlation with commuting trips (r = 0.32 and 0.21, respectively). The correlation between modeled home

  18. Percentile Analysis for Goodness-of-Fit Comparisons of Models to Data

    Science.gov (United States)

    2014-07-01

    obtaining a high R2. One solution to the problem is to consider a metric that is both sensitive to the number of data points under investigation as well...other facets of the model (e.g., its parsimony, breath, and ability; see Cassimatis, Bello , & Langley, 2008). 4. Model A and Model B have...278. Busemeyer, J. R. & Diederich, A. (2010). Cognitive Modeling. Sage. Cassimatis, N., Bello , P. & Langley, P. (2008). Ability, breadth and

  19. What Is Good Communication?

    Science.gov (United States)

    Spitzberg, Brian H.

    2000-01-01

    Explores issues entailed in defining good communication including multiple reasonable criteria, competency bias, and communication as a function of context, locus, and abstraction. Claims good communication is a subjective evaluation and not subject to being codified in reductionist models. (NH)

  20. Promoting pollution prevention through community-industry dialogues: the good neighbor model in Minnesota.

    Science.gov (United States)

    Murdock, Barbara Scott; Sexton, Ken

    2002-05-15

    This article examines five attempts by communities to promote pollution prevention through direct negotiations with local manufacturing plants. These projects were Good Neighbor Dialogues spearheaded by Citizens for a Better Environment-Minnesota, an environmental advocacy organization. Three community-company partnerships (a container plant, a foundry, and a cabinet manufacturer) were successful and two (a munitions plant and a petroleum refinery) were not. Successful dialogues all shared certain characteristics: the company was open to negotiating with the community; there was an effective "champion" within the company; a skilled, independent facilitator served as moderator; community participants received independent technical assistance; and both the company and community understood the value of cooperative environmental decision making. Results suggest that Good Neighbor Dialogues can, under the right settings and circumstances, be an effective mechanism for building social capital by fostering greater understanding and trust between companies and communities. They offer the prospect of community-company partnerships that promote pollution prevention and other environmental improvements, while at the same time reinforcing and amplifying traditional pollution control strategies.

  1. Near-Quantitative Agreement of Model-Free DFT-MD Predictions with XAFS Observations of the Hydration Structure of Highly Charged Transition-Metal Ions.

    Science.gov (United States)

    Fulton, John L; Bylaska, Eric J; Bogatko, Stuart; Balasubramanian, Mahalingam; Cauët, Emilie; Schenter, Gregory K; Weare, John H

    2012-09-20

    First-principles dynamics simulations (DFT, PBE96, and PBE0) and electron scattering calculations (FEFF9) provide near-quantitative agreement with new and existing XAFS measurements for a series of transition-metal ions interacting with their hydration shells via complex mechanisms (high spin, covalency, charge transfer, etc.). This analysis does not require either the development of empirical interparticle interaction potentials or structural models of hydration. However, it provides consistent parameter-free analysis and improved agreement with the higher-R scattering region (first- and second-shell structure, symmetry, dynamic disorder, and multiple scattering) for this comprehensive series of ions. DFT+GGA MD methods provide a high level of agreement. However, improvements are observed when exact exchange is included. Higher accuracy in the pseudopotential description of the atomic potential, including core polarization and reducing core radii, was necessary for very detailed agreement. The first-principles nature of this approach supports its application to more complex systems.

  2. Helen Huntingdon——A Good Model for Women of All Times

    Institute of Scientific and Technical Information of China (English)

    李兆平; 仲锡

    2008-01-01

    Anne Bront? was the youngest of the Bront? sisters.Together the three sisters left a brilliant page in the history of English literature.Her work The Tenant of Wildfell Hall was a great success the moment it was published and was highly praised by many outstanding British critics.He heroine in the book,Helen Huntingdon,was a young lady with noble-minded and gentle nature.With her spirit of self-esteem and self-reliance as well as her wonderful deed of slamming her bedroom door against her husband,Helen fought bravely with the inequality between men and women in the old British society in the mid 19th century.The purpose of this article is to pay good tribute to Helen's great personality,and moreover,to acknowledge and reorganize the almost forgotten literary genius Anne Bront?.

  3. How good is the Prevent model for estimating the health benefits of prevention?

    DEFF Research Database (Denmark)

    Brønnum-Hansen, Henrik

    1999-01-01

    Prevent is a public health model for estimating the effect on mortality of changes in exposure to risk factors. When the model is tested by simulating a development that has already taken place, the results may differ considerably from the actual situation. The purpose of this study is to test th...

  4. Goodness-of-fit tests and model diagnostics for negative binomial regression of RNA sequencing data.

    Directory of Open Access Journals (Sweden)

    Gu Mi

    Full Text Available This work is about assessing model adequacy for negative binomial (NB regression, particularly (1 assessing the adequacy of the NB assumption, and (2 assessing the appropriateness of models for NB dispersion parameters. Tools for the first are appropriate for NB regression generally; those for the second are primarily intended for RNA sequencing (RNA-Seq data analysis. The typically small number of biological samples and large number of genes in RNA-Seq analysis motivate us to address the trade-offs between robustness and statistical power using NB regression models. One widely-used power-saving strategy, for example, is to assume some commonalities of NB dispersion parameters across genes via simple models relating them to mean expression rates, and many such models have been proposed. As RNA-Seq analysis is becoming ever more popular, it is appropriate to make more thorough investigations into power and robustness of the resulting methods, and into practical tools for model assessment. In this article, we propose simulation-based statistical tests and diagnostic graphics to address model adequacy. We provide simulated and real data examples to illustrate that our proposed methods are effective for detecting the misspecification of the NB mean-variance relationship as well as judging the adequacy of fit of several NB dispersion models.

  5. Goodness-of-fit tests and model diagnostics for negative binomial regression of RNA sequencing data.

    Science.gov (United States)

    Mi, Gu; Di, Yanming; Schafer, Daniel W

    2015-01-01

    This work is about assessing model adequacy for negative binomial (NB) regression, particularly (1) assessing the adequacy of the NB assumption, and (2) assessing the appropriateness of models for NB dispersion parameters. Tools for the first are appropriate for NB regression generally; those for the second are primarily intended for RNA sequencing (RNA-Seq) data analysis. The typically small number of biological samples and large number of genes in RNA-Seq analysis motivate us to address the trade-offs between robustness and statistical power using NB regression models. One widely-used power-saving strategy, for example, is to assume some commonalities of NB dispersion parameters across genes via simple models relating them to mean expression rates, and many such models have been proposed. As RNA-Seq analysis is becoming ever more popular, it is appropriate to make more thorough investigations into power and robustness of the resulting methods, and into practical tools for model assessment. In this article, we propose simulation-based statistical tests and diagnostic graphics to address model adequacy. We provide simulated and real data examples to illustrate that our proposed methods are effective for detecting the misspecification of the NB mean-variance relationship as well as judging the adequacy of fit of several NB dispersion models.

  6. Every good regulator of a system must be a model of that system

    Directory of Open Access Journals (Sweden)

    Pieter Eykhoff

    1994-07-01

    Full Text Available A model for the process under control - do or don't we really need it? Some elementary philosophical considerations confirming such a need, are well supported by examples of various 'optimal' control schemes. How does this affirmation influence the requirements to identification and the implemcntation of control using such a model?

  7. Preserving the Public Good: Presenting an Organizational Model for the Changing Future of Higher Education

    Science.gov (United States)

    Garcia, Stephanie Parra

    2011-01-01

    Institutions of higher education face financial pressure to become self-sustaining (Gumport, 2001; 2000). This rapidly growing economic demand is negatively affecting the social mission of higher education (Kezar, 2004). Scholars suggest the implementation of a new model of higher education, one that blends a for-profit model with the traditional…

  8. Good Modeling Practice for PAT Applications: Propagation of Input Uncertainty and Sensitivity Analysis

    DEFF Research Database (Denmark)

    Sin, Gürkan; Gernaey, Krist; Eliasson Lantz, Anna

    2009-01-01

    The uncertainty and sensitivity analysis are evaluated for their usefulness as part of the model-building within Process Analytical Technology applications. A mechanistic model describing a batch cultivation of Streptomyces coelicolor for antibiotic production was used as case study. The input...

  9. Selecting a Dynamic Simulation Modeling Method for Health Care Delivery Research—Part 2: Report of the ISPOR Dynamic Simulation Modeling Emerging Good Practices Task Force

    NARCIS (Netherlands)

    Marshall, Deborah A.; Burgos-Liz, Lina; IJzerman, Maarten Joost; Crown, William; Padula, William V.; Wong, Peter K.; Pasupathy, Kalyan S.; Higashi, Mitchell K.; Osgood, Nathaniel D.

    2015-01-01

    In a previous report, the ISPOR Task Force on Dynamic Simulation Modeling Applications in Health Care Delivery Research Emerging Good Practices introduced the fundamentals of dynamic simulation modeling and identified the types of health care delivery problems for which dynamic simulation modeling

  10. Selecting a Dynamic Simulation Modeling Method for Health Care Delivery Research—Part 2: Report of the ISPOR Dynamic Simulation Modeling Emerging Good Practices Task Force

    NARCIS (Netherlands)

    Marshall, Deborah A.; Burgos-Liz, Lina; IJzerman, Maarten Joost; Crown, William; Padula, William V.; Wong, Peter K.; Pasupathy, Kalyan S.; Higashi, Mitchell K.; Osgood, Nathaniel D.

    2015-01-01

    In a previous report, the ISPOR Task Force on Dynamic Simulation Modeling Applications in Health Care Delivery Research Emerging Good Practices introduced the fundamentals of dynamic simulation modeling and identified the types of health care delivery problems for which dynamic simulation modeling c

  11. Economic Order Quality Model for Determining the Sales Prices of Fresh Goods at Various Points in Time

    Directory of Open Access Journals (Sweden)

    Po-Yu Chen

    2017-01-01

    Full Text Available Although the safe consumption of goods such as food products, medicine, and vaccines is related to their freshness, consumers frequently understand less than suppliers about the freshness of goods when they purchase them. Because of this lack of information, apart from sales prices, consumers refer only to the manufacturing and expiration dates when deciding whether to purchase and how many of these goods to buy. If dealers could determine the sales price at each point in time and customers’ intention to buy goods of varying freshness, then dealers could set an optimal inventory cycle and allocate a weekly sales price for each point in time, thereby maximizing the profit per unit time. Therefore, in this study, an economic order quality model was established to enable discussion of the optimal control of sales prices. The technique for identifying the optimal solution for the model was determined, the characteristics of the optimal solution were demonstrated, and the implications of the solution’s sensitivity analysis were explained.

  12. Good Cell Culture Practice for stem cells and stem-cell-derived models.

    Science.gov (United States)

    Pamies, David; Bal-Price, Anna; Simeonov, Anton; Tagle, Danilo; Allen, Dave; Gerhold, David; Yin, Dezhong; Pistollato, Francesca; Inutsuka, Takashi; Sullivan, Kristie; Stacey, Glyn; Salem, Harry; Leist, Marcel; Daneshian, Mardas; Vemuri, Mohan C; McFarland, Richard; Coecke, Sandra; Fitzpatrick, Suzanne C; Lakshmipathy, Uma; Mack, Amanda; Wang, Wen Bo; Yamazaki, Daiju; Sekino, Yuko; Kanda, Yasunari; Smirnova, Lena; Hartung, Thomas

    2017-01-01

    The first guidance on Good Cell Culture Practice (GCCP) dates back to 2005. This document expands this to include aspects of quality assurance for in vitro cell culture focusing on the increasingly diverse cell types and culture formats used in research, product development, testing and manufacture of biotechnology products and cell-based medicines. It provides a set of basic principles of best practice that can be used in training new personnel, reviewing and improving local procedures, and helping to assure standard practices and conditions for the comparison of data between laboratories and experimentation performed at different times. This includes recommendations for the documentation and reporting of culture conditions. It is intended as guidance to facilitate the generation of reliable data from cell culture systems, and is not intended to conflict with local or higher level legislation or regulatory requirements. It may not be possible to meet all recommendations in this guidance for practical, legal or other reasons. However, when it is necessary to divert from the principles of GCCP, the risk of decreasing the quality of work and the safety of laboratory staff should be addressed and any conclusions or alternative approaches justified. This workshop report is considered a first step toward a revised GCCP 2.0.

  13. Building of Reusable Reverse Logistics Model and its Optimization Considering the Decision of Backorder or Next Arrival of Goods

    Science.gov (United States)

    Lee, Jeong-Eun; Gen, Mitsuo; Rhee, Kyong-Gu; Lee, Hee-Hyol

    This paper deals with the building of the reusable reverse logistics model considering the decision of the backorder or the next arrival of goods. The optimization method to minimize the transportation cost and to minimize the volume of the backorder or the next arrival of goods occurred by the Just in Time delivery of the final delivery stage between the manufacturer and the processing center is proposed. Through the optimization algorithms using the priority-based genetic algorithm and the hybrid genetic algorithm, the sub-optimal delivery routes are determined. Based on the case study of a distilling and sale company in Busan in Korea, the new model of the reusable reverse logistics of empty bottles is built and the effectiveness of the proposed method is verified.

  14. Robust goodness-of-fit tests for AR(p) models based on L1-norm fitting

    Institute of Scientific and Technical Information of China (English)

    蒋建成; 郑忠国

    1999-01-01

    A robustified residual autocorrelation is defined based on L1-regression. Under very general conditions,the asymptotic distribution of the robust residual autocorrelation is obtained. A robustified portmanteau statistic is then constructed which can be used in checking the goodness-of-fit of AR(p) models when using L1-norm fitting. Empirical results show that L1-norm estimators and the proposed portmanteau statistic are robust against outliers, error distributions, and accuracy for a given finite sample.

  15. TEACHING AND LEARNING WITH TECHNOLOGY: A THEORETICAL MODEL FOR GOOD EDUCATIONAL PRACTICES WITH ICT

    Directory of Open Access Journals (Sweden)

    Jesús Valverde Berrocoso

    2010-02-01

    Full Text Available This article aims to define a theoretical explanatory framework for the integration of information technologies and communication technologies (ICT in education from the perspective of teacher education. The initial and continuing training of teachers is characterized by a tendency towards "essentialisation" of technology and generation of users who do not usually think about educational uses of technology in their own contexts. Our research on the integration of ICT in the classroom has allowed us to observe the lack of connection between the personal and professional use of teachers of these technological tools, as well as the need for training is geared towards developing skills and knowledge to examine, in a critical manner, the educational implications of these new teaching aids. This article is based on the proposed Koehler & Mishra (2005, 2006, 2007 and 2008 called TPCK (Technological Pedagogical Content Knowledge which is based on the construct of PCK Shulman (1987 to which is added the concept of "Technology" (T to those of "Pedagogy" (P and "Curriculum Content" (C. Connections and dynamic interactions between these three key components leading to different components to be considered in understanding the processes of integration of ICT in schools. Good educational practices with ICT are multidimensional and complex actions that require (1 understand the representation and formulation of concepts and procedures for their understanding through ICT, (2 develop constructivist teaching strategies that use ICT for teaching content curriculum, (3 know the difficulties in learning concepts and how ICT can help overcome them, and (4 knowing the students' prior knowledge and the epistemology of the curriculum to understand how ICT can be used to build on pre-existing knowledge and develop new epistemologies. These skills clearly go beyond the isolation that has an expert in a curriculum (teacher of a discipline, an expert in IT (engineer, or an

  16. As Good as Married? A Model of Premarital Cohabitation and Learning

    NARCIS (Netherlands)

    Sahib, Padma Rao; Gu, Xinhua

    2013-01-01

    This article develops a two-sided search-matching model with imperfectly observed types and sequential learning. We use the metaphor of premarital cohabitation and assume that it is initiated to learn more about one's prospective spouse. We show that couples match within classes and that the classes

  17. An Application of Structural Equation Modeling for Developing Good Teaching Characteristics Ontology

    Science.gov (United States)

    Phiakoksong, Somjin; Niwattanakul, Suphakit; Angskun, Thara

    2013-01-01

    Ontology is a knowledge representation technique which aims to make knowledge explicit by defining the core concepts and their relationships. The Structural Equation Modeling (SEM) is a statistical technique which aims to explore the core factors from empirical data and estimates the relationship between these factors. This article presents an…

  18. Have Cognitive Diagnostic Models Delivered Their Goods? Some Substantial and Methodological Concerns

    Science.gov (United States)

    Wilhelm, Oliver; Robitzsch, Alexander

    2009-01-01

    The paper by Rupp and Templin (2008) is an excellent work on the characteristics and features of cognitive diagnostic models (CDM). In this article, the authors comment on some substantial and methodological aspects of this focus paper. They organize their comments by going through issues associated with the terms "cognitive," "diagnostic" and…

  19. As Good as Married? A Model of Premarital Cohabitation and Learning

    NARCIS (Netherlands)

    Sahib, Padma Rao; Gu, Xinhua

    2013-01-01

    This article develops a two-sided search-matching model with imperfectly observed types and sequential learning. We use the metaphor of premarital cohabitation and assume that it is initiated to learn more about one's prospective spouse. We show that couples match within classes and that the classes

  20. Lack of predictability of classical animal models for hypolipidemic activity: A good time for mice?

    NARCIS (Netherlands)

    Krause, B.R.; Princen, H.M.G.

    1998-01-01

    Hypolipidemic drugs that are efficacious in man are not always active in classical animal models of dyslipidemia. Inhibitors of HMG-CoA reductase (statins) do not lower plasma cholesterol in rats, but yet this species was alone in providing activity for fibrate-type drugs. Nicotinic acid possesses m

  1. Substandard model? At last, a good reason to opt for a sexier theory of particle physics

    CERN Multimedia

    Cho, A

    2001-01-01

    According to experimenters at Brookhaven, a tiny discrepancy in the magnetism of the muon may signal a crack in the Standard Model. The deviation could be the first piece of hard evidence for a more complete theory called supersymmetry (1 page).

  2. Design of an integrated forward and reverse logistics network optimi-zation model for commercial goods management

    Directory of Open Access Journals (Sweden)

    Eva Ponce-Cueto

    2015-01-01

    Full Text Available In this study, an optimization model is formulated for designing an integrated forward and reverse logistics network in the consumer goods industry. The resultant model is a mixed-integer linear programming model (MILP. Its purpose is to minimize the total costs of the closed-loop supply chain network. It is important to note that the design of the logistics network may involve a trade-off between the total costs and the optimality in commercial goods management. The model comprises a discrete set as potential locations of unlimited capacity warehouses and fixed locations of customers’ zones. It provides decisions related to the facility location and customers’ requirements satisfaction, all of this related with the inventory and shipment decisions of the supply chain. Finally, an application of this model is illustrated by a real-life case in the food and drinks industry. We can conclude that this model can significantly help companies to make decisions about problems associated with logistics network design.

  3. Good and bad consequences of altered fatty acid metabolism in heart failure: evidence from mouse models.

    Science.gov (United States)

    Abdurrachim, Desiree; Luiken, Joost J F P; Nicolay, Klaas; Glatz, Jan F C; Prompers, Jeanine J; Nabben, Miranda

    2015-05-01

    The shift in substrate preference away from fatty acid oxidation (FAO) towards increased glucose utilization in heart failure has long been interpreted as an oxygen-sparing mechanism. Inhibition of FAO has therefore evolved as an accepted approach to treat heart failure. However, recent data indicate that increased reliance on glucose might be detrimental rather than beneficial for the failing heart. This review discusses new insights into metabolic adaptations in heart failure. A particular focus lies on data obtained from mouse models with modulations of cardiac FA metabolism at different levels of the FA metabolic pathway and how these differently affect cardiac function. Based on studies in which these mouse models were exposed to ischaemic and non-ischaemic heart failure, we discuss whether and when modulations in FA metabolism are protective against heart failure.

  4. MODELING AND SOLVING A RICH VEHICLE ROUTING PROBLEM FOR THE DELIVERY OF GOODS IN URBAN AREAS

    OpenAIRE

    José Ferreira de Souza Neto; Vitória Pureza

    2016-01-01

    ABSTRACT This work addresses a vehicle routing problem that aims at representing delivery operations of large volumes of products in dense urban areas. Inspired by a case study in a drinks producer and distributor, we propose a mathematical programming model and solution approaches that take into account costs with own and chartered vehicles, multiple deliverymen, time windows in customers, compatibility of vehicles and customers, time limitations for the circulation of large vehicles in city...

  5. Good Governance

    Directory of Open Access Journals (Sweden)

    S de la Harpe

    2008-08-01

    Full Text Available This issue of the Potchefstroom Electronic Law Journal (PELJ is entirely dedicated to the concept of good governance. It is the outcome of the first Summer/Winter school on Good Governance which was held at North-West University, Potchefstroom (SA in January 2006 and at Tilburg University, Tilburg (NL in January 2007. This Summer/Winter school has now become a yearly event with a bi-annual theme. Academic staff from both universities collaborate in teaching this course. Students from the two universities who participate in the Summer/Winter school have the unique possibility to deepen their knowledge on a particular subject while enjoying a cross-cultural learning environment. The subject of good governance was not selected by chance but was chosen because of its impact in many fields and the many ways in which the concept is used. It was time for a deeper insight into this multiple role of the concept of good governance. The contributions to this journal are the analytical outcome of the research done in preparation for the lectures given during the Summer/Winter school. As the contributions directly apply the good governance concept to various specific fields of expertise, this introduction will be used to give a short reflection on the concept as such.

  6. MODELING AND SOLVING A RICH VEHICLE ROUTING PROBLEM FOR THE DELIVERY OF GOODS IN URBAN AREAS

    Directory of Open Access Journals (Sweden)

    José Ferreira de Souza Neto

    Full Text Available ABSTRACT This work addresses a vehicle routing problem that aims at representing delivery operations of large volumes of products in dense urban areas. Inspired by a case study in a drinks producer and distributor, we propose a mathematical programming model and solution approaches that take into account costs with own and chartered vehicles, multiple deliverymen, time windows in customers, compatibility of vehicles and customers, time limitations for the circulation of large vehicles in city centers and multiple daily trips. Results with instances based on real data provided by the company highlight the potential of applicability of some of the proposed methods.

  7. Accidental goodness?

    DEFF Research Database (Denmark)

    Richter, Anne

    In postmodern capitalist market economies, management of the single organisation is bound to be guided by several rationales, which are in conflict with each other. For some writers this perception leads to the argument, that conceptions of management should strive towards goals beyond the present...... society. For others, the handling of plural perspectives is just a management discipline. However these positions seem to share a focus on organization as a the arena for the organization of the good. The contribution looks at the management of occupational accidents as an example of striving for good...

  8. Testing the Agreement/Tense Omission Model: Why the Data on Children's Use of Non-Nominative 3psg Subjects Count against the ATOM

    Science.gov (United States)

    Pine, Julian M.; Rowland, Caroline F.; Lieven, Elena V. M.; Theakston, Anna L.

    2005-01-01

    One of the most influential recent accounts of pronoun case-marking errors in young children's speech is Schutze & Wexler's (1996) Agreement/Tense Omission Model (ATOM). The ATOM predicts that the rate of agreeing verbs with non-nominative subjects will be so low that such errors can be reasonably disregarded as noise in the data. The present…

  9. hESCCO: development of good practice models for hES cell derivation.

    Science.gov (United States)

    Franklin, Sarah B; Hunt, Charles; Cornwell, Glenda; Peddie, Valerie; Desousa, Paul; Livie, Morag; Stephenson, Emma L; Braude, Peter R

    2008-01-01

    One response of the UK research community to the public sensitivity and logistical complexity of embryo donation to stem cell research has been the formation of a national network of 'human embryonic stem cell coordinators' (hESCCO). The aim of hESCCO is to contribute to the formation and implementation of national standards for hES cell derivation and banking, in particular the ethical protocols for patient information and informed consent. The hESCCO project is an innovative practical intervention within the broader attempt to establish greater transparency, consistency, efficiency and standardization of hES derivation in the UK. A major outcome of the hESCCO initiative has been the drafting and implementation of a national consent form. The lessons learned in this context may be relevant to other practitioners and regulators as a model of best practice in hES cell derivation.

  10. Is the Mouse a Good Model of Human PPARγ-Related Metabolic Diseases?

    Science.gov (United States)

    Pap, Attila; Cuaranta-Monroy, Ixchelt; Peloquin, Matthew; Nagy, Laszlo

    2016-01-01

    With the increasing number of patients affected with metabolic diseases such as type 2 diabetes, obesity, atherosclerosis and insulin resistance, academic researchers and pharmaceutical companies are eager to better understand metabolic syndrome and develop new drugs for its treatment. Many studies have focused on the nuclear receptor peroxisome proliferator-activated receptor gamma (PPARγ), which plays a crucial role in adipogenesis and lipid metabolism. These studies have been able to connect this transcription factor to several human metabolic diseases. Due to obvious limitations concerning experimentation in humans, animal models—mainly mouse models—have been generated to investigate the role of PPARγ in different tissues. This review focuses on the metabolic features of human and mouse PPARγ-related diseases and the utility of the mouse as a model. PMID:27483259

  11. Is the BEHI Index (Part of the BANCS Model Good for Prediction of Streambank Erosion?

    Directory of Open Access Journals (Sweden)

    Zuzana Allmanová

    2016-01-01

    Full Text Available Sedimentation of waterways and reservoirs, decreasing quality of drinking water and costs necessary for maintenance of these objects directly related to streambank erosion. This study provides a tool for water management that can help with estimation parts of a streambank which are prone to erosion. The Bank erosion hazard index (BEHI part of the BANCS (Bank Assessment for Non‑point source Consequences of Sediment model is one of the several procedures for assessing streambank erosion condition and potential (Rosgen, 2001. On May 15th 2014 a high precipitation occurred in the watershed of Sestrč torrent, in the eastern part of Chočské vrchy (Sp = 27.64 km2. It reached 102.7 mm per 24 hours. The rainfall resulted in extreme streambank erosion. We started the research of annual stream bank erosion on Sestrč in the beginning of May 2014 and we established 19 experimental sections on the stream. Occurrence of heavy rainfall allowed us to erosion rates after flash flood. The aim of this paper was to verify, if BEHI index can really determine the most vulnerable parts of a banks to erosion. We measured erosion rates Eb (m3/m using a bank pins and toe pin (Sass, 2011 on each experimental section and evaluated each section by BEHI index (Rosgen, 2001, 2008. The results were statistically verified and confirmed a strong relationship between BEHI and real damage of banks Eb (m3/m (R: 0.88, R2: 0.78.

  12. Good Vibrations

    OpenAIRE

    Panesar, Lucy

    2007-01-01

    Good Vibrations was a market research exercise conducted by Felicity (my alter-ego) and assistants to help develop marketing and packaging for an electro-therapeutic device (vibrator) used to treat hysteria and other female stress related disorders. It was a live art work commissioned by The Live Art Development Agency for East End Collaborations on 6th May 2007 and the South London Gallery for Bonkersfest on 2nd June 2007.

  13. Agreement Workflow Tool (AWT)

    Data.gov (United States)

    Social Security Administration — The Agreement Workflow Tool (AWT) is a role-based Intranet application used for processing SSA's Reimbursable Agreements according to SSA's standards. AWT provides...

  14. The structure of personality of a good teacher from students perspective according to the Big-Five model

    Directory of Open Access Journals (Sweden)

    Genc Lajoš

    2014-01-01

    Full Text Available This paper deals with the identification of desirable personality characteristics of teachers from students perspective in the Big-Five Model of personality from a phenomenological approach. The description of personality of a good teacher was obtained from students of the University of Novi Sad (n=443. The Big Five Inventory (BFI was applied with the instruction to respond to claims as a good teacher would answer. The students’ estimates indicate that a good teacher is expected to have lower emotional instability, but more pronounced extroversion, openness to experience, cooperativeness (pleasantness and consciousness with regard to referent values in general population. For the domain of neuroticism, the difference is either small or medium in size, for cooperativeness of a medium size, and for extroversion, consciousness and openness to experience the difference is large. The gender of students does not influence their expectations. Methodological dilemmas in this area of research and implications of the results for the selection and professional development of teachers are discussed. [Projekat Ministarstva nauke Republike Srbije, br. 179010 i br. 47020

  15. Comments on the Paper `A new basic 1-dimensional 1-layer model obtains excellent agreement with the observed Earth temperature' by Rainer Link and Horst-Joachim L\\"udecke

    CERN Document Server

    Kramm, Gerhard

    2011-01-01

    In our comments on the paper of Link and L\\"udecke we document that these authors used rather improper quotations of our paper. They also argued on the basis of false claims regarding our mathematical and physical description of both the global energy balance model of Schneider and Mass and the Dines-type two-layer energy balance model for the Earth-atmosphere system. They completely disregarded the respective literature. They claimed excellent agreement between their predicted Earth's surface temperature and the observed one even though they only reproduced the temperature by an inverse application of the power law of Stefan and Boltzmann. They also claimed that their result for the increase in the Earth's surface temperature of about 1.1 K due to the doubling of the atmospheric CO2 concentration is in good agreement with the IPCC value if no feedback is considered. However, beside the fact that this result is not based on model predictions, it also disagrees with the definition of the anthropogenic radiativ...

  16. Work, Health, Music: The enduring Rusyn model of a good life amid changing socioeconomic contexts of progress

    Directory of Open Access Journals (Sweden)

    K. M. Cantin

    2013-11-01

    Full Text Available Rusyns in Eastern and Central Europe have experience with two predominant models of “progress”: the Soviet-style communist and the neoliberal.  Proponents of each system promised to better the lives of all but did not take into account what “better” meant to local populations, including Rusyns.  Increasingly, European governmental and nongovernmental organizations are redefining notions of progress and development to accord with values of sustainability and a capability approach (CA to well-being.  Giovanola (2005 and Robeyns (2005 have argued that scholars of the CA need to better develop concepts of “personhood” and “human flourishing”, and to better explain the importance of social group membership and norms to living a valued life.  The emerging anthropological focus on well-being, emphasizing culturally specific definitions of what happiness and a good life mean, can provide these conceptualizations.  As a case in point, I use freelist and interview data obtained from residents in the Prešov Region of Slovakia and the Zakarpattia Oblast of Ukraine along with Rusyn cultural narratives drawn from poems, folktales, plays, songs, interviews, and speeches to identify prevalent models of “personhood” and “a good life”. I discuss how these narratives intersect and diverge with discourses of happiness and progress along with the implications for Rusyns' ability to flourish. 

  17. Is my model good enough? Best practices for verification and validation of musculoskeletal models and simulations of movement.

    Science.gov (United States)

    Hicks, Jennifer L; Uchida, Thomas K; Seth, Ajay; Rajagopal, Apoorva; Delp, Scott L

    2015-02-01

    Computational modeling and simulation of neuromusculoskeletal (NMS) systems enables researchers and clinicians to study the complex dynamics underlying human and animal movement. NMS models use equations derived from physical laws and biology to help solve challenging real-world problems, from designing prosthetics that maximize running speed to developing exoskeletal devices that enable walking after a stroke. NMS modeling and simulation has proliferated in the biomechanics research community over the past 25 years, but the lack of verification and validation standards remains a major barrier to wider adoption and impact. The goal of this paper is to establish practical guidelines for verification and validation of NMS models and simulations that researchers, clinicians, reviewers, and others can adopt to evaluate the accuracy and credibility of modeling studies. In particular, we review a general process for verification and validation applied to NMS models and simulations, including careful formulation of a research question and methods, traditional verification and validation steps, and documentation and sharing of results for use and testing by other researchers. Modeling the NMS system and simulating its motion involves methods to represent neural control, musculoskeletal geometry, muscle-tendon dynamics, contact forces, and multibody dynamics. For each of these components, we review modeling choices and software verification guidelines; discuss variability, errors, uncertainty, and sensitivity relationships; and provide recommendations for verification and validation by comparing experimental data and testing robustness. We present a series of case studies to illustrate key principles. In closing, we discuss challenges the community must overcome to ensure that modeling and simulation are successfully used to solve the broad spectrum of problems that limit human mobility.

  18. A new, integrated, continuous purification process template for monoclonal antibodies: Process modeling and cost of goods studies.

    Science.gov (United States)

    Xenopoulos, Alex

    2015-11-10

    An evolving biopharmaceutical industry requires advancements in biomanufacturing that offer increased productivity and improved economics without sacrificing process robustness. Accordingly, we have developed a new monoclonal antibody purification template comprised of flocculation-based clarification, capture by continuous multi-column protein A chromatography and flow-through polishing. The new process offers a robust, single-use manufacturing solution while significantly reducing overall cost of goods. Modeling studies verify that the individual clarification, capture and polishing solutions offer significant advantages as stand-alone unit operations. These technologies were also designed to be integrated into a continuous purification template. Process modeling studies have been used to highlight both cost and operational advantages of the new process template. Depending on scale, savings of more than 20% and 60% were seen for commercial and clinical operation, respectively. Integrating the technologies into a continuous process consistently offered additional cost advantages. During template development, process modeling was instrumental in highlighting the importance of identifying technologies that provided high product yield and purification factors. Additionally, high product concentration and eliminating the need for intermediate product dilution emerged as important considerations for newly developed unit operations. Combining experimental work with insights from modeling can significantly improve the outcome of product and process development.

  19. Dynamic transmission modeling: a report of the ISPOR-SMDM Modeling Good Research Practices Task Force Working Group-5.

    NARCIS (Netherlands)

    Pitman, Richard; Fisman, David; Zaric, Gregory S; Postma, Maarten; Kretzschmar, Mirjam; Edmunds, John; Brisson, Marc; ISPOR-SMDM Modeling Good Research Practices Task Force, [No Value

    2012-01-01

    The transmissible nature of communicable diseases is what sets them apart from other diseases modeled by health economists. The probability of a susceptible individual becoming infected at any one point in time (the force of infection) is related to the number of infectious individuals in the popula

  20. Dynamic transmission modeling: a report of the ISPOR-SMDM Modeling Good Research Practices Task Force Working Group-5.

    NARCIS (Netherlands)

    Pitman, Richard; Fisman, David; Zaric, Gregory S; Postma, Maarten; Kretzschmar, Mirjam; Edmunds, John; Brisson, Marc; ISPOR-SMDM Modeling Good Research Practices Task Force, [No Value

    2012-01-01

    The transmissible nature of communicable diseases is what sets them apart from other diseases modeled by health economists. The probability of a susceptible individual becoming infected at any one point in time (the force of infection) is related to the number of infectious individuals in the popula

  1. Dynamic transmission modeling: a report of the ISPOR-SMDM Modeling Good Research Practices Task Force Working Group-5.

    NARCIS (Netherlands)

    Pitman, Richard; Fisman, David; Zaric, Gregory S; Postma, Maarten; Kretzschmar, Mirjam; Edmunds, John; Brisson, Marc; ISPOR-SMDM Modeling Good Research Practices Task Force, [No Value

    2012-01-01

    The transmissible nature of communicable diseases is what sets them apart from other diseases modeled by health economists. The probability of a susceptible individual becoming infected at any one point in time (the force of infection) is related to the number of infectious individuals in the

  2. Intraperitoneal Administration of Low Dose Aluminium in The Rat: How Good is It to Produce a Model for Alzheimer Disease.

    Science.gov (United States)

    Ulusoy, H B; Sonmez, M F; Kilic, E; Caliskan, K; Karaca, B; Kara, M; Ercal, O; Gunduz, Y; Karabulut, D; Bitiktas, S; Tan, B; Kavraal, S; İnal, A; Suer, C

    2015-12-01

    Since neurotoxicity of aluminium (Al) resembles the progressive neurodegeneration observed in Alzheimer Disease (AD), Al administration in several ways has been used to produce AD model. Intraperitoneal (ip) low dose (4.2 mg/ kg) Al injection in rats for long periods is the preferred method by some researchers. In this paper, the efficiency of this method for producing an AD model was evaluated. In this study, we looked at the neuropathology of Al and the characteristic lesions of AD by histological and immunohistochemical techniques and determined oxidative stress markers in the brains of Al-treated and control rats. We also made electrophysiological recordings at the hippocampus and evaluated possible behavioural changes by Morris water maze test. However, no pathologic changes occurred in the animals except for an impairment in long-term potentiation (LTP) in the hippocampus (e.g. the LTPs of population spike (PS) amplitude at 15 min post-tetanus were measured as 217±27% in Al-treated rats and as 240±42% in sham-treated rats, of baseline PS amplitude). According to the findings of the present study, low dose of ip Al in rats is not sufficient to produce a good AD model. Higher doses (≥10 mg/kg) should be used.

  3. A Time for Flexible Donor Agreements.

    Science.gov (United States)

    Fischer, Gerald B.

    2003-01-01

    Discusses why volatile markets and new donor expectations make now a good time to rework payout rates and gift agreements to bolster financial and strategic performance. Suggests seven options for action. (EV)

  4. Good Manufacturing Practices (GMP) manufacturing of advanced therapy medicinal products: a novel tailored model for optimizing performance and estimating costs.

    Science.gov (United States)

    Abou-El-Enein, Mohamed; Römhild, Andy; Kaiser, Daniel; Beier, Carola; Bauer, Gerhard; Volk, Hans-Dieter; Reinke, Petra

    2013-03-01

    Advanced therapy medicinal products (ATMP) have gained considerable attention in academia due to their therapeutic potential. Good Manufacturing Practice (GMP) principles ensure the quality and sterility of manufacturing these products. We developed a model for estimating the manufacturing costs of cell therapy products and optimizing the performance of academic GMP-facilities. The "Clean-Room Technology Assessment Technique" (CTAT) was tested prospectively in the GMP facility of BCRT, Berlin, Germany, then retrospectively in the GMP facility of the University of California-Davis, California, USA. CTAT is a two-level model: level one identifies operational (core) processes and measures their fixed costs; level two identifies production (supporting) processes and measures their variable costs. The model comprises several tools to measure and optimize performance of these processes. Manufacturing costs were itemized using adjusted micro-costing system. CTAT identified GMP activities with strong correlation to the manufacturing process of cell-based products. Building best practice standards allowed for performance improvement and elimination of human errors. The model also demonstrated the unidirectional dependencies that may exist among the core GMP activities. When compared to traditional business models, the CTAT assessment resulted in a more accurate allocation of annual expenses. The estimated expenses were used to set a fee structure for both GMP facilities. A mathematical equation was also developed to provide the final product cost. CTAT can be a useful tool in estimating accurate costs for the ATMPs manufactured in an optimized GMP process. These estimates are useful when analyzing the cost-effectiveness of these novel interventions. Copyright © 2013 International Society for Cellular Therapy. Published by Elsevier Inc. All rights reserved.

  5. Agreement in Bloomfield.

    Science.gov (United States)

    Langendoen, D. Terence; McDaniel, Dana S.

    A discussion of Leonard Bloomfield's theory on grammatical agreement examines agreement within Bloomfield's overall scheme of syntactic analysis and relates it to current work in syntax. Bloomfield's three types of agreement (concord, government, and cross-reference) are outlined and compared to the contemporary distinction between pro-drop and…

  6. Assessing agreement in measurements of orthodontic study models: Digital caliper on plaster models vs 3-dimensional software on models scanned by structured-light scanner.

    Science.gov (United States)

    Wan Hassan, Wan Nurazreena; Othman, Siti Adibah; Chan, Chee Seng; Ahmad, Roshahida; Ali, Siti Nor'Ain; Abd Rohim, Anis

    2016-11-01

    In this study we aimed to compare measurements on plaster models using a digital caliper, and on 3-dimensional (3D) digital models, produced using a structured-light scanner, using 3D software. Fifty digital models were scanned from the same plaster models. Arch and tooth size measurements were made by 2 operators, twice. Calibration was done on 10 sets of models and checked using the Pearson correlation coefficient. Data were analyzed by error variances, repeatability coefficient, repeated-measures analysis of variance, and Bland-Altman plots. Error variances ranged between 0.001 and 0.044 mm for the digital caliper method, and between 0.002 and 0.054 mm for the 3D software method. Repeated-measures analysis of variance showed small but statistically significant differences (P plaster models and were, therefore, clinically acceptable. Copyright © 2016. Published by Elsevier Inc.

  7. Asymptotics of the goodness-of-fit test for a partial linear model with randomly censored data

    Institute of Scientific and Technical Information of China (English)

    CHEN; Min(

    2003-01-01

    (semiparametric) partial and generalized spline models, Ann. Statist., 1988, 16: 113.[16]Eubank, R. L., Spiegeman, C. H., Testing the goodness of fit of a linear model via nonparametric regression techniques, J. Amer. Statist. Assoc., 1990, 85: 387.[17]Hardle, W., Mammen, E., Comparing non-parametric versus parametric regression fits, Ann. Statist., 1993,21: 1926.[18]Hardle, W., Mammen, E., Müller, M., Testing parametric versus semiparametric modeling in generalized linear models, J. Amer. Statist. Assoc., 1998, 93: 1461.[19]Hardle, W., Marron, J. S., Semiparametric comparison of regression curves, Ann. Statist., 1990, 18: 63.[20]King, G., Testing the equality of two regression curves using linear smoothers, Statist. & Probab. Lett., 1991,12: 239.[21]Miiller, H. G., Goodness-of-fit diagnostic for regression models, Sand. J. Statist., 1993, 19: 157.[22]Stute, W., Nonparametric model checks for regression, Ann. Statist., 1997, 25: 613.[23]Stute, W., Mantetga, G., Quindimil, M. P., Bootstrap approximations in model cheeks for regression, J. Amer.Statist. Assoc., 1998, 93: 141.[24]Stute, W., Thies, S., Zhu, L. X., Model checks for regression: An innovation process approach, Ann. Statist.,1998, 26: 1916.[25]Stute, W., Nonlinear censored regression, Statistica Sinica, 1999, 9:1089.[26]Wang, Q. H., Zhu, L. X., Estimation in partial linear error-in-variables models with censored data, Commun.in Statist. The. and Meth., 2001, .[27]Lo, S. H., Singh, K., The product-limit estimator and the bootstrap: some asymptotic representations, Probab.Theory and Related Fields, 1986, 71: 455.[28]Zhou, M., Some properties of the Kaplan-Meier estimator for independent, nonidentically distributed random variables, Ann. Statist., 1991, 19: 2266.[29]Hall, P., Heyde, C. C., Martingale Limit Theory and Its Applications, New York: Academic Press, 1980.[30]Pollard, D., Convergence of Stochastic Processes, New York: Springer-Verlag, 1984.[31

  8. Measurement of Consumer Based Brand Equity Using Structural Equation Modeling and A Research in Durable Consumer Goods Sector

    Directory of Open Access Journals (Sweden)

    Cagatan Taskin

    2010-04-01

    Full Text Available In today’s markets, many products are perceived to be similar because of information and commuication technologies that are developing fastly. In spite of this, enterprises should make their products different and unique to compete in a sustainable manner. Besides, marketing strategies based solely on concepts such as price, quality, product differentiation and appropriate payment options, may not always provide sustainable competitive advantages under today’s severe competition conditions. Consumer based brand equity, which can be also defined as the meaning of a brand to the consumer, is one of the basic ways of developing sustainable and efficient marketing srategies. The aim of this research is to explore the relationships between consumer based brand equity of a durable consumer good brand, namely Bosch and its dimensions by means of structural equation modeling and to show how to use the model for developing efficient marketing strategies with strategy propositions. The research is conducted in Bursa, so the results of this study can not be generalized to Turkey or any other cities.

  9. Does a wife's education influence spousal agreement on approval of family planning?: Random-effects Modeling using data from two West African Countries.

    Science.gov (United States)

    Hossain, Mian; Ahmed, Saifuddin; Rogers, Laurencia

    2014-05-01

    Spousal approval of family planning is critical for contraceptive use. Both contraceptive use rates and women's education are low in many West-African countries and this study examines the role of wives' education in spousal agreement on approval of family planning in two sub-Saharan West African countries. We used couples' data from Demographic Health Surveys in Senegal and in Niger, conducted in 2005 and 2006, respectively. Multiple logistic regression results using multilevel modeling show that the odds of spousal agreement on approval of family planning were slightly over three times [OR: 3.16; 95% CI: 1.32 to 7.57] in Senegal and were about three times [OR: 3.07; 95% CI: 1.64 to 5.76] in Niger higher for women with more than primary education. Findings suggest that improvement in women's education could lead to spousal agreement on approval of family planning, which may lead to use of family planning in sub-Saharan African countries.

  10. Symmetry in behavior of complex social systems - discussion of models of crowd evacuation organized in agreement with symmetry conditions

    CERN Document Server

    Sikora, W

    2011-01-01

    The evacuation of football stadium scenarios are discussed as model realizing ordered states, described as movements of individuals according to fields of displacements, calculated correspondingly to given scenario. The symmetry of the evacuation space is taken into account in calculation of displacements field - the displacements related to every point of this space are presented in the coordinate frame in the best way adapted to given symmetry space group, which the set of basic vectors of irreducible representation of given group is. The speeds of individuals at every point in the presented model have the same quantity. As the results the times of evacuation and average forces acting on individuals during the evacuation are given. Both parameters are compared with the same parameters got without symmetry considerations. They are calculated in the simulation procedure. The new program (using modified Helbing model) has been elaborated and presented in this work for realization the simulation tasks the.

  11. Analysis Of Agricultural Productivity And Growth On Safta (South Asian Free Trade Agreement) And Its Imact On Economy Of Pakistan By Using CGE Model

    OpenAIRE

    Nazir Ahmed GOPANG; SZABAC Dokri; F. M. Shaikh

    2010-01-01

    This research explore the opportunities and analyzing the cost andbenefit on Pak-India trade on South Asian Free Trade Agreement (SAFTA)and its possible impact on the welfare of both countries. Pak-India trade on SAFTA create opportunities for the both countries in export Laid growth. In First Scenario when normal trading relation will be restores and given MFN(Most Favored Nations) status given to each other to attack the trade between two countries. The Global trade analysis GTAP model is u...

  12. Agreement of central site measurements and land use regression modeled oxidative potential of PM2.5 with personal exposure

    NARCIS (Netherlands)

    Yang, Aileen; Hoek, Gerard; Montagne, Denise; Leseman, Daan L A C; Hellack, Bryan; Kuhlbusch, Thomas A J; Cassee, Flemming R; Brunekreef, Bert; Janssen, Nicole A H

    2015-01-01

    Oxidative potential (OP) of ambient particulate matter (PM) has been suggested as a health-relevant exposure metric. In order to use OP for exposure assessment, information is needed about how well central site OP measurements and modeled average OP at the home address reflect temporal and spatial v

  13. Long-Range Models of Modified Gravity and Their Agreement with Solar System and Double Pulsar Data

    CERN Document Server

    Iorio, Lorenzo

    2009-01-01

    Many long-range modifications of the Newtonian/Einsteinian standard laws of gravity have been proposed in the recent past to explain various celestial phenomena occurring at different scales ranging from solar system to the entire universe. The most famous ones are the so-called Pioneer anomaly, {i.e.} a still unexplained acceleration detected in the telemetry of the Pioneer 10/11 spacecraft after they passed the 20 AU threshold in the solar system, the non-Keplerian profiles of the velocity rotation curves of several galaxies and the cosmic acceleration. We use the latest observational determinations of the planetary motions in the solar system and in the double pulsar system to put constraints on such models independently of the phenomena for which they were originally proposed. We also deal with the recently detected anomalous perihelion precession of Saturn and discuss the possibility that it can be explained by some of the aforementioned models of modified gravity.

  14. Combined density functional/polarizable continuum model study of magnetochiral birefringence: Can theory and experiment be brought to agreement?

    Science.gov (United States)

    Jansík, Branislav; Rizzo, Antonio; Frediani, Luca; Ruud, Kenneth; Coriani, Sonia

    2006-12-01

    The magnetic-field-induced axial birefringence (magnetochirality) of five closed-shell chiral molecules (three substituted oxiranes, carvone, and limonene) is studied at the density functional theory level using Becke's 3-parameter Lee-Yang-Parr functional and frequency-dependent quadratic response theory. The influence of the environment and the conformational distribution on the property is also studied. The environment effects are described by the polarizable continuum model in its integral-equation formulation. The effect of the conformational distribution is investigated by performing calculations on several conformers—for carvone and limonene—followed by Boltzmann averaging. The calculated values for the magnetochiral birefringence are compared to previous ab initio results and experimental data where available. The refined model presented here brings the ab initio values closer to experiment. Still, disagreements remain in some cases and it appears difficult to resolve these discrepancies.

  15. Customs control of goods

    Directory of Open Access Journals (Sweden)

    Mentor Gashi

    2015-11-01

    Full Text Available Customs control, is regulated by law in different countries. Different countries define through the law, the control of goods.. Main purpose of this paper is to analyze two types of customs controls, and their effect in reducing avoidance of duty or tax evasion which may be caused by the import of goods of certain companies. For this reason we researched which model is implemented in developing countries and what results were reached through questionnaires. In this sense the next research question, consists in defining the moment of customs control pre or post-clearance control of goods.

  16. Customs control of goods

    OpenAIRE

    Mentor Gashi; Ramadan Gashi

    2015-01-01

    Customs control, is regulated by law in different countries. Different countries define through the law, the control of goods.. Main purpose of this paper is to analyze two types of customs controls, and their effect in reducing avoidance of duty or tax evasion which may be caused by the import of goods of certain companies. For this reason we researched which model is implemented in developing countries and what results were reached through questionnaires. In this sense the next research que...

  17. Quality of life in relation to future mental health problems and offending: Testing the good lives model among detained girls.

    Science.gov (United States)

    Van Damme, Lore; Hoeve, Machteld; Vermeiren, Robert; Vanderplasschen, Wouter; Colins, Olivier F

    2016-06-01

    Detained girls bear high levels of criminal behavior and mental health problems that are likely to persist into young adulthood. Research with these girls began primarily from a risk management perspective, whereas a strength-based empowering perspective may increase knowledge that could improve rehabilitation. This study examines detained girls' quality of life (QoL) in relation to future mental health problems and offending, thereby testing the strength-based good lives model of offender rehabilitation (GLM). At baseline, 95 girls (Mage = 16.25) completed the World Health Organization QoL instrument to assess their QoL prior to detention in the domains of physical health, psychological health, social relationships, and environment. Six months after discharge, mental health problems and offending were assessed by self-report measures. Structural equation models were conducted to test GLM's proposed (in)direct pathways from QoL (via mental health problems) toward offending. Although we could not find support for GLM's direct negative pathway from QoL to offending, our findings did provide support for GLM's indirect negative pathway via mental health problems to future offending. In addition, we found a direct positive pathway from detained girls' satisfaction with their social relationships to offending after discharge. The current findings support the potential relevance of addressing detained girls' QoL, pursuing the development of new skills, and supporting them to build constructive social contacts. Our findings, however, also show that clinicians should not only focus on strengths but that detecting and modifying mental health problems in this vulnerable group is also warranted. (PsycINFO Database Record

  18. THE GIFT AGREEMENT

    Directory of Open Access Journals (Sweden)

    Ljupka B.Petrevska

    2014-04-01

    Full Text Available The gift agreement is a bilateral legal contract which is concluded between the donor and the recipiet of a gift, which could be a thing or a property right. It includes no compensation for the donor but requires mutual agreement. Under certain circumstances the gift agreement may be revoked, and it could be done by the conlcuding parts or third parts, all of which cases are stipulated by law more or less precisely from country to country.

  19. Shareholders' agreements in Denmark

    DEFF Research Database (Denmark)

    Werlauff, Erik

    2010-01-01

    ’ agreements”) cannot bind the company within the sense of company law under the new state of law, and voting rights agreements, agreements on right of pre-emption etc. will therefore only apply at the level of contract law between the parties to the agreement. This article for European Business Law Review...... (on the basis of unwritten principles of loyalty under contract law) to vote for such a repetition of the central provisions of the owners’ agreement in the articles of association is then analysed....

  20. The effect of maternal psychopathology on parent-child agreement of child anxiety symptoms: A hierarchical linear modeling approach.

    Science.gov (United States)

    Affrunti, Nicholas W; Woodruff-Borden, Janet

    2015-05-01

    The current study examined the effects of maternal anxiety, worry, depression, child age and gender on mother and child reports of child anxiety using hierarchical linear modeling. Participants were 73 mother-child dyads with children between the ages of 7 and 10 years. Reports of child anxiety symptoms, including symptoms of specific disorders (e.g., social phobia) were obtained using concordant versions of the Screen for Anxiety and Related Emotional Disorders (SCARED). Children reported significantly higher levels of anxiety symptoms relative to their mothers. Maternal worry and depression predicted for significantly lower levels of maternal-reported child anxiety and increasing discrepant reports. Maternal anxiety predicted for higher levels of maternal-reported child anxiety and decreasing discrepant reports. Maternal depression was associated with increased child-reported child anxiety symptoms. No significant effect of child age or gender was observed. Findings may inform inconsistencies in previous studies on reporter discrepancies. Implications and future directions are discussed. Copyright © 2015 Elsevier Ltd. All rights reserved.

  1. Selecting a dynamic simulation modeling method for health care delivery research-part 2: report of the ISPOR Dynamic Simulation Modeling Emerging Good Practices Task Force.

    Science.gov (United States)

    Marshall, Deborah A; Burgos-Liz, Lina; IJzerman, Maarten J; Crown, William; Padula, William V; Wong, Peter K; Pasupathy, Kalyan S; Higashi, Mitchell K; Osgood, Nathaniel D

    2015-03-01

    In a previous report, the ISPOR Task Force on Dynamic Simulation Modeling Applications in Health Care Delivery Research Emerging Good Practices introduced the fundamentals of dynamic simulation modeling and identified the types of health care delivery problems for which dynamic simulation modeling can be used more effectively than other modeling methods. The hierarchical relationship between the health care delivery system, providers, patients, and other stakeholders exhibits a level of complexity that ought to be captured using dynamic simulation modeling methods. As a tool to help researchers decide whether dynamic simulation modeling is an appropriate method for modeling the effects of an intervention on a health care system, we presented the System, Interactions, Multilevel, Understanding, Loops, Agents, Time, Emergence (SIMULATE) checklist consisting of eight elements. This report builds on the previous work, systematically comparing each of the three most commonly used dynamic simulation modeling methods-system dynamics, discrete-event simulation, and agent-based modeling. We review criteria for selecting the most suitable method depending on 1) the purpose-type of problem and research questions being investigated, 2) the object-scope of the model, and 3) the method to model the object to achieve the purpose. Finally, we provide guidance for emerging good practices for dynamic simulation modeling in the health sector, covering all aspects, from the engagement of decision makers in the model design through model maintenance and upkeep. We conclude by providing some recommendations about the application of these methods to add value to informed decision making, with an emphasis on stakeholder engagement, starting with the problem definition. Finally, we identify areas in which further methodological development will likely occur given the growing "volume, velocity and variety" and availability of "big data" to provide empirical evidence and techniques

  2. The Helsinki Agreement

    Science.gov (United States)

    Babel: Journal of the Australian Federation of Modern Language Teachers' Associations, 1977

    1977-01-01

    A reprint of sections of the Helsinki agreement dealing with foreign languages and civilization, and cooperation and exchanges in the field of education. The agreement supports wider knowledge of foreign languages and promotes exchanges, cooperation, lexicography, and specialized programs in adult education. (AMH)

  3. Agreement on African Venture

    Institute of Scientific and Technical Information of China (English)

    LAN XINZHEN

    2010-01-01

    @@ China's biggest aluminum producer Aluminum Corp.China Ltd.(Chalco) signed a binding agreement with the world's second largest mining company,Rio Tinto,on July 29 in Beijing.The agreement will establish a joint venture to develop and operate the Simandou iron ore project in Guinea,Africa.

  4. Supporting good practice in the provision of services to people with comorbid mental health and alcohol and other drug problems in Australia: describing key elements of good service models

    Directory of Open Access Journals (Sweden)

    Canaway Rachel

    2010-12-01

    Full Text Available Abstract Background The co-occurrence of mental illness and substance use problems (referred to as "comorbidity" in this paper is common, and is often reported by service providers as the expectation rather than the exception. Despite this, many different treatment service models are being used in the alcohol and other drugs (AOD and mental health (MH sectors to treat this complex client group. While there is abundant literature in the area of comorbidity treatment, no agreed overarching framework to describe the range of service delivery models is apparent internationally or at the national level. The aims of the current research were to identify and describe elements of good practice in current service models of treatment of comorbidity in Australia. The focus of the research was on models of service delivery. The research did not aim to measure the client outcomes achieved by individual treatment services, but sought to identify elements of good practice in services. Methods Australian treatment services were identified to take part in the study through a process of expert consultation. The intent was to look for similarities in the delivery models being implemented across a diverse set of services that were perceived to be providing good quality treatment for people with comorbidity problems. Results A survey was designed based on a concept map of service delivery devised from a literature review. Seventeen Australian treatment services participated in the survey, which explored the context in which services operate, inputs such as organisational philosophy and service structure, policies and procedures that guide the way in which treatment is delivered by the service, practices that reflect the way treatment is provided to clients, and client impacts. Conclusions The treatment of people with comorbidity of mental health and substance use disorders presents complex problems that require strong but flexible service models. While the treatment

  5. Supporting good practice in the provision of services to people with comorbid mental health and alcohol and other drug problems in Australia: describing key elements of good service models.

    Science.gov (United States)

    Merkes, Monika; Lewis, Virginia; Canaway, Rachel

    2010-12-03

    The co-occurrence of mental illness and substance use problems (referred to as "comorbidity" in this paper) is common, and is often reported by service providers as the expectation rather than the exception. Despite this, many different treatment service models are being used in the alcohol and other drugs (AOD) and mental health (MH) sectors to treat this complex client group. While there is abundant literature in the area of comorbidity treatment, no agreed overarching framework to describe the range of service delivery models is apparent internationally or at the national level. The aims of the current research were to identify and describe elements of good practice in current service models of treatment of comorbidity in Australia. The focus of the research was on models of service delivery. The research did not aim to measure the client outcomes achieved by individual treatment services, but sought to identify elements of good practice in services. Australian treatment services were identified to take part in the study through a process of expert consultation. The intent was to look for similarities in the delivery models being implemented across a diverse set of services that were perceived to be providing good quality treatment for people with comorbidity problems. A survey was designed based on a concept map of service delivery devised from a literature review. Seventeen Australian treatment services participated in the survey, which explored the context in which services operate, inputs such as organisational philosophy and service structure, policies and procedures that guide the way in which treatment is delivered by the service, practices that reflect the way treatment is provided to clients, and client impacts. The treatment of people with comorbidity of mental health and substance use disorders presents complex problems that require strong but flexible service models. While the treatment services included in this study reflected the diversity of

  6. Summary of Model Toxics Control Act (MTCA) Potential Impacts Related to Hanford Cleanup and the Tri-Party Agreement (TPA)

    Energy Technology Data Exchange (ETDEWEB)

    IWATATE, D.F.

    2000-07-14

    This white paper provides an initial assessment of the potential impacts of the Model Toxics Control Act (MTCA) regulations (and proposed revisions) on the Hanford site cleanup and addresses concerns that MTCA might impose inappropriate or unachievable clean-up levels and drive clean-up costs higher. The white paper and supporting documentation (Appendices A and B) provide DOE with a concise and up-to-date review of potential MTCA impacts to cost and schedule for the Hanford site activities. MTCA, Chapter 70.105D RCW, is the State of Washington's risk based law governing clean-up of contaminated sites and is implemented by The Washington Department of Ecology (Ecology) under the MTCA Clean-up Regulations, Chapter 173-340 WAC. Hanford cleanup is subject to the MTCA requirements as Applicable, Relevant and Appropriate Requirements (ARARs) for those areas of Hanford being managed under the authority of the Federal Resource Conservation and Recovery Act (RCRA), Comprehensive Environmental Response, Compensation and Liability Act (CERCLA), and the state Dangerous Waste Regulations. MTCA provides Ecology with authority to implement site clean-up actions under both the federal RCRA and CERCLA regulations as well as the state regulations. Most of the Hanford clean-up actions are being implemented under the CERCLA program, however, there is a trend is toward increased use of MTCA procedures and standards. The application of MTCA to the Hanford clean-up has been an evolving process with some of the Hanford clean-up actions considering MTCA standards as an ARAR and using MTCA procedures for remedy selection. The increased use and application of MTCA standards and procedures could potentially impact both cost and schedule for the Hanford cleanup.

  7. The Homomorphic Key Agreement

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    There are various challenges that are faced in group communication, so it is necessary to ensure session key. Key agreement is the fundamental cryptographic primitive for establishing a secure communication. It is a process of computing a shared secret contributed by two or more entities such that no single node can predetermine the resulting value. An authenticated key agreement is attained by combining the key agreement protocol with digital signatures. After a brief introduction to existing key agreement in group communication, Making use of the additive-multiplicative homomorphism in the integer ring defined by Sander and Tschudin: A new protocols, called the homomorphism key agreement, was designed, which can be self-contributory, robust, scalable and applicable in group communication.

  8. Quantitative agreement between [(15)O]H2O PET and model free QUASAR MRI-derived cerebral blood flow and arterial blood volume.

    Science.gov (United States)

    Heijtel, D F R; Petersen, E T; Mutsaerts, H J M M; Bakker, E; Schober, P; Stevens, M F; van Berckel, B N M; Majoie, C B L M; Booij, J; van Osch, M J P; van Bavel, E T; Boellaard, R; Lammertsma, A A; Nederveen, A J

    2016-04-01

    The purpose of this study was to assess whether there was an agreement between quantitative cerebral blood flow (CBF) and arterial cerebral blood volume (CBVA) measurements by [(15)O]H2O positron emission tomography (PET) and model-free QUASAR MRI. Twelve healthy subjects were scanned within a week in separate MRI and PET imaging sessions, after which quantitative and qualitative agreement between both modalities was assessed for gray matter, white matter and whole brain region of interests (ROI). The correlation between CBF measurements obtained with both modalities was moderate to high (r(2): 0.28-0.60, P QUASAR significantly underestimated CBF by 30% (P QUASAR yielding values that were only 27% of the [(15)O]H2O-derived values (P QUASAR MRI, indicating similar qualitative CBVA and CBF information by both modalities. In conclusion, the results of this study demonstrate that QUASAR MRI and [(15)O]H2O PET provide similar CBF and CBVA information, but with systematic quantitative discrepancies. Copyright © 2016 John Wiley & Sons, Ltd.

  9. Analysis Of Agricultural Productivity And Growth On Safta (South Asian Free Trade Agreement And Its Imact On Economy Of Pakistan By Using CGE Model

    Directory of Open Access Journals (Sweden)

    Nazir Ahmed GOPANG

    2010-02-01

    Full Text Available This research explore the opportunities and analyzing the cost andbenefit on Pak-India trade on South Asian Free Trade Agreement (SAFTAand its possible impact on the welfare of both countries. Pak-India trade on SAFTA create opportunities for the both countries in export Laid growth. In First Scenario when normal trading relation will be restores and given MFN(Most Favored Nations status given to each other to attack the trade between two countries. The Global trade analysis GTAP model is used to analyze the possible impact of SAFTA on Pakistan in a multi country, multi sector applied General equilibrium frame work. After employing the simplified static analysis framework, the analysis based on simulations revealsthat current demand for Pakistani Basmati Rice and other consumer items like leather and cotton-made garments will expand after the FTA and consumer surplus will increase. The export of Rice, leather and cotton-made garments may be conducted by two scenarios, i.e. when normal trading relations between Pakistan and India will be restored and when there will be a free trade between Pakistan and India in the presence of South Asian Free Trade Agreement (SAFTA. Results based on this research reveal that on SAFTA, grounds, there will be net export benefi ts in Pakistan’s economy.

  10. 19 CFR 10.457 - Fungible goods and materials.

    Science.gov (United States)

    2010-04-01

    ... Trade Agreement Rules of Origin § 10.457 Fungible goods and materials. (a) A person claiming preferential tariff treatment under the US-CFTA for a good may claim that a fungible good or material...

  11. Financial Giffen Goods

    DEFF Research Database (Denmark)

    Poulsen, Rolf; Rasmussen, Kourosh Marjani

    2008-01-01

    In the basic Markowitz and Merton models, a stock’s weight in efficient portfolios goes up if its expected rate of return goes up. Put differently, there are no financial Giffen goods. By an example from mortgage choice we illustrate that for more complicated portfolio problems Giffen effects do...

  12. Gender agreement and multiple referents.

    Science.gov (United States)

    Finocchiaro, Chiara; Mahon, Bradford Z; Caramazza, Alfonso

    2008-01-01

    We report a new pattern of usage in current, spoken Italian that has implications for both psycholinguistic models of language production and linguistic theories of language change. In Italian, gender agreement is mandatory for both singular and plural nouns. However, when two or more nouns of different grammatical gender appear in a conjoined noun phrase (NP), masculine plural agreement is required. In this study, we combined on-line and off-line methodologies in order to assess the mechanisms involved in gender marking in the context of multiple referents. The results of two pronoun production tasks showed that plural feminine agreement was significantly more difficult than plural masculine agreement. In a separate study using offline judgements of acceptability, we found that agreement violations in Italian are tolerated more readily in the case of feminine conjoined noun phrases (e.g., la mela e la banana 'the:fem apple:fem and the: fem banana: fem') than masculine conjoined noun phrases (e.g., il fiore e il libro 'the:mas flower: mas and the:mas book:mas'). Implications of these results are discussed both at the level of functional architecture within the language production system and at the level of changes in language use.

  13. Gender agreement and multiple referents

    Science.gov (United States)

    Finocchiaro, Chiara; Mahon, Bradford Z.; Caramazza, Alfonso

    2010-01-01

    We report a new pattern of usage in current, spoken Italian that has implications for both psycholinguistic models of language production and linguistic theories of language change. In Italian, gender agreement is mandatory for both singular and plural nouns. However, when two or more nouns of different grammatical gender appear in a conjoined noun phrase (NP), masculine plural agreement is required. In this study, we combined on-line and off-line methodologies in order to assess the mechanisms involved in gender marking in the context of multiple referents. The results of two pronoun production tasks showed that plural feminine agreement was significantly more difficult than plural masculine agreement. In a separate study using offline judgements of acceptability, we found that agreement violations in Italian are tolerated more readily in the case of feminine conjoined noun phrases (e.g., la mela e la banana ‘the:fem apple:fem and the: fem banana: fem’) than masculine conjoined noun phrases (e.g., il fiore e il libro ‘the:mas flower: mas and the:mas book:mas’). Implications of these results are discussed both at the level of functional architecture within the language production system and at the level of changes in language use.* PMID:21037930

  14. Agreement of central site measurements and land use regression modeled oxidative potential of PM{sub 2.5} with personal exposure

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Aileen, E-mail: Yang@uu.nl [National Institute for Public Health and the Environment (RIVM), P.O. Box 1, 3720BA Bilthoven (Netherlands); Institute for Risk Assessment Sciences, Division Environmental Epidemiology, Utrecht University, P.O. Box 80.178, 3508TD Utrecht (Netherlands); Hoek, Gerard; Montagne, Denise [Institute for Risk Assessment Sciences, Division Environmental Epidemiology, Utrecht University, P.O. Box 80.178, 3508TD Utrecht (Netherlands); Leseman, Daan L.A.C. [National Institute for Public Health and the Environment (RIVM), P.O. Box 1, 3720BA Bilthoven (Netherlands); Hellack, Bryan [Air Quality & Sustainable Nanotechnology, Institute of Energy and Environmental Technology (IUTA), e.V., Blierheimer Str. 58-60, 47229 Duisburg (Germany); Kuhlbusch, Thomas A.J. [Air Quality & Sustainable Nanotechnology, Institute of Energy and Environmental Technology (IUTA), e.V., Blierheimer Str. 58-60, 47229 Duisburg (Germany); Center for Nanointegration Duisburg-Essen (CENIDE), University Duisburg-Essen, Carl-Benz-Straße 199, 47057 Duisburg (Germany); Cassee, Flemming R. [National Institute for Public Health and the Environment (RIVM), P.O. Box 1, 3720BA Bilthoven (Netherlands); Institute for Risk Assessment Sciences, Division Environmental Epidemiology, Utrecht University, P.O. Box 80.178, 3508TD Utrecht (Netherlands); Brunekreef, Bert [Institute for Risk Assessment Sciences, Division Environmental Epidemiology, Utrecht University, P.O. Box 80.178, 3508TD Utrecht (Netherlands); Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht (Netherlands); Janssen, Nicole A.H. [National Institute for Public Health and the Environment (RIVM), P.O. Box 1, 3720BA Bilthoven (Netherlands)

    2015-07-15

    Oxidative potential (OP) of ambient particulate matter (PM) has been suggested as a health-relevant exposure metric. In order to use OP for exposure assessment, information is needed about how well central site OP measurements and modeled average OP at the home address reflect temporal and spatial variation of personal OP. We collected 96-hour personal, home outdoor and indoor PM{sub 2.5} samples from 15 volunteers living either at traffic, urban or regional background locations in Utrecht, the Netherlands. OP was also measured at one central reference site to account for temporal variations. OP was assessed using electron spin resonance (OP{sup ESR}) and dithiothreitol (OP{sup DTT}). Spatial variation of average OP at the home address was modeled using land use regression (LUR) models. For both OP{sup ESR} and OP{sup DTT}, temporal correlations of central site measurements with home outdoor measurements were high (R>0.75), and moderate to high (R=0.49–0.70) with personal measurements. The LUR model predictions for OP correlated significantly with the home outdoor concentrations for OP{sup DTT} and OP{sup ESR} (R=0.65 and 0.62, respectively). LUR model predictions were moderately correlated with personal OP{sup DTT} measurements (R=0.50). Adjustment for indoor sources, such as vacuum cleaning and absence of fume-hood, improved the temporal and spatial agreement with measured personal exposure for OP{sup ESR}. OP{sup DTT} was not associated with any indoor sources. Our study results support the use of central site OP for exposure assessment of epidemiological studies focusing on short-term health effects. - Highlights: • Oxidative potential (OP) of PM was proposed as a health-relevant exposure metric. • We evaluated the relationship between measured and modeled outdoor and personal OP. • Temporal correlations of central site with personal OP are moderate to high. • Adjusting for indoor sources improved the agreement with personal OP. • Our results

  15. Gravity, Bilateral Agreements, and Trade Diversion in the Americas

    OpenAIRE

    Raymond Robertson; Antoni Estevadeordal

    2009-01-01

    Krishna (1998) shows that a bilateral agreement between two countries render a multilateral agreement less attractive if the bilateral agreement is trade diverting. This paper combines Krishna’s model with the empirical approach of Anderson and va

  16. International Fisheries Agreements

    DEFF Research Database (Denmark)

    Pintassilgo, Pedro; Kronbak, Lone Grønbæk; Lindroos, Marko

    2015-01-01

    This paper surveys the application of game theory to the economic analysis of international fisheries agreements. The relevance of this study comes not only from the existence of a vast literature on the topic but especially from the specific features of these agreements. The emphasis of the survey...... and stability of international fisheries agreements. A key message that emerges from this literature strand is that self-enforcing cooperative management of internationally shared fish stocks is generally difficult to achieve. Hence, the international legal framework and regulations play a decisive role...... is on coalition games, an approach that has become prominent in the fisheries economics literature over the last decade. It is shown that coalition games were first applied to international fisheries agreements in the late 1990s addressing cooperative issues under the framework of characteristic function games...

  17. Trade Agreements PTI

    Data.gov (United States)

    Department of Homeland Security — The objective of the Trade Agreements PTI is to advance CBP’s mission by working with internal and external stakeholders to facilitate legitimate trade and address...

  18. Service level agreements.

    Science.gov (United States)

    Grimwood, A

    1998-02-01

    Service level agreements provide clearer descriptions of the services to be provided and the objectives to be met. In many instances it is the first time that services have been defined allowing their performance to be suitably measured. They should be output based and not too prescriptive on how the services are to be delivered. The emphasis should be on establishing outputs and the arrangements for monitoring achievement. Customer expectations can exceed available resources and arbitration may become necessary if agreement cannot be reached on internal service level agreements. The main requirements of customers for change through service level agreements is usually improved communications on job status that includes notification of any delays and that agreed response times will be met.

  19. Cooperative Fire Protection Agreement

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The purpose of this Agreement is to provide for cooperation in the prevention, detection and suppression of wildland fires within the protection areas designated in...

  20. Good Faith and Game Theory

    DEFF Research Database (Denmark)

    Rose, Caspar

    2016-01-01

    This article shows how game theory can be applied to model good faith mathematically using an example of a classic legal dispute related to rei vindicato. The issue is whether an owner has a legal right to his good if a person has bought it in good faith by using updated probabilities. The article...

  1. Codes of Good Governance

    DEFF Research Database (Denmark)

    Beck Jørgensen, Torben; Sørensen, Ditte-Lene

    2013-01-01

    Good governance is a broad concept used by many international organizations to spell out how states or countries should be governed. Definitions vary, but there is a clear core of common public values, such as transparency, accountability, effectiveness, and the rule of law. It is quite likely......, however, that national views of good governance reflect different political cultures and institutional heritages. Fourteen national codes of conduct are analyzed. The findings suggest that public values converge and that they match model codes from the United Nations and the European Council as well...... as conceptions of good governance from other international organizations. While values converge, they are balanced and communicated differently, and seem to some extent to be translated into the national cultures. The set of global public values derived from this analysis include public interest, regime dignity...

  2. Determination of Agreement Between Laboratory Instruments.

    Science.gov (United States)

    Gray, Tonya E.; Pratt, Manley C.; Cusick, Patrick K.

    1999-03-01

    The present study was conducted to illustrate the utility of Bland-Altman plots for use by our laboratory staff and other non-statisticians in assessing the agreement between values measured by using two different laboratory instruments. A high degree of agreement reflects acceptable interchangeability of equipment and minimal effect on clinical decision-making. We have summarized literature that suggests that the regression line and correlation coefficient used with regression analysis, although commonly employed, are not appropriate first choices for evaluating agreement. Using the ABL 500 Radiometer and i-STAT Portable Chemistry Analyzer, we evaluated pH, PCO2, and TCO2. Bland-Altman plots were simple to produce, were not mathematics-intensive, and provided an easily interpreted, graphical answer to the question of agreement between instruments. For purposes of clinical decision-making, the ABL and i-STAT machines were found to be in good agreement for the tests evaluated.

  3. A Nonparametric Approach for Assessing Goodness-of-Fit of IRT Models in a Mixed Format Test

    Science.gov (United States)

    Liang, Tie; Wells, Craig S.

    2015-01-01

    Investigating the fit of a parametric model plays a vital role in validating an item response theory (IRT) model. An area that has received little attention is the assessment of multiple IRT models used in a mixed-format test. The present study extends the nonparametric approach, proposed by Douglas and Cohen (2001), to assess model fit of three…

  4. Assessing Goodness of Fit in Item Response Theory with Nonparametric Models: A Comparison of Posterior Probabilities and Kernel-Smoothing Approaches

    Science.gov (United States)

    Sueiro, Manuel J.; Abad, Francisco J.

    2011-01-01

    The distance between nonparametric and parametric item characteristic curves has been proposed as an index of goodness of fit in item response theory in the form of a root integrated squared error index. This article proposes to use the posterior distribution of the latent trait as the nonparametric model and compares the performance of an index…

  5. Segmentation Similarity and Agreement

    CERN Document Server

    Fournier, Chris

    2012-01-01

    We propose a new segmentation evaluation metric, called segmentation similarity (S), that quantifies the similarity between two segmentations as the proportion of boundaries that are not transformed when comparing them using edit distance, essentially using edit distance as a penalty function and scaling penalties by segmentation size. We propose several adapted inter-annotator agreement coefficients which use S that are suitable for segmentation. We show that S is configurable enough to suit a wide variety of segmentation evaluations, and is an improvement upon the state of the art. We also propose using inter-annotator agreement coefficients to evaluate automatic segmenters in terms of human performance.

  6. Assimilation of TOPEX/POSEIDON Altimeter Data into a Global Ocean Circulation Model: Are the Results Any Good?

    Science.gov (United States)

    Fukumori, I.; Fu, L. L.; Chao, Y.

    1998-01-01

    The feasibility of assimilating satellite altimetry data into a global ocean general ocean general circulation model is studied. Three years of TOPEX/POSEIDON data is analyzed using a global, three-dimensional, nonlinear primitive equation model.

  7. Applying the Bollen-Stine Bootstrap for Goodness-of-Fit Measures to Structural Equation Models with Missing Data.

    Science.gov (United States)

    Enders, Craig K.

    2002-01-01

    Proposed a method for extending the Bollen-Stine bootstrap model (K. Bollen and R. Stine, 1992) fit to structural equation models with missing data. Developed a Statistical Analysis System macro program to implement this procedure, and assessed its usefulness in a simulation. The new method yielded model rejection rates close to the nominal 5%…

  8. FFTF Authorization Agreement

    Energy Technology Data Exchange (ETDEWEB)

    DAUTEL, W.A.

    2000-02-25

    The purpose of the Authorization Agreement is to serve as a mechanism whereby the U.S. Department of Energy, Richland Operations Office (RL) and Fluor Hanford (FH) jointly clarify and agree to key conditions for conducting work safely and efficiently.

  9. Bad Beta, Good Beta

    OpenAIRE

    Campbell, John; Vuolteenaho, Tuomo

    2003-01-01

    This paper explains the size and value "anomalies" in stock returns using an economically motivated two-beta model. We break the beta of a stock with the market portfolio into two components, one reflecting news about the market's future cash flows and one reflecting news about the market's discount rates. Intertemporal asset pricing theory suggests that the former should have a higher price of risk; thus beta, like cholesterol, comes in "had" and "good" varieties. Empirically, we find that v...

  10. Cultural Interest Goods as Public Goods

    Directory of Open Access Journals (Sweden)

    Juan Manuel Vargas-Ayala

    2017-01-01

    Full Text Available This paper presents the debate regarding the nature of goods of cultural interest as public goods, discussion until now overlooked by the legal doctrine in Administrative Law. Through the exam of judicial decisions, it seeks to question their inalienable character, and their aptitude to be acquired by the State, case in which they shift their nature into public goods.

  11. Intra- and inter-observer agreement on diagnosis of Dupuytren disease, measurements of severity of contracture, and disease extent.

    Science.gov (United States)

    Broekstra, Dieuwke C; Lanting, Rosanne; Werker, Paul M N; van den Heuvel, Edwin R

    2015-08-01

    Dupuytren disease (DD) is a fibrosing disease affecting the palmar aponeurosis, and is mostly treated by surgery based on measurement of severity of flexion contracture of the fingers. Literature concerning the measurement reliability is scarce. This study aimed to determine the intra- and inter-observer agreement of four variables for diagnosing DD, determining severity of contracture, and disease extent. One of them is a new measurement on the area of nodules and cords for measuring the disease extent in early disease stages. An agreement study (n = 54) was performed by two trained investigators. Agreement was calculated per finger, based on an intraclass correlation coefficient (ICC) using a latent variable model on subjects for diagnosis and Tubiana stage. For total passive extension deficit (TPED) and the area of nodules and cords, agreement was calculated with an ICC using a one-way random effects model with subject as random effect. Inter-observer agreement was very good for diagnosing DD (ICC: 95.5%-99.9%) and good to very good for classifying Tubiana stage (ICC: 73.5%-94.9%). Agreements for area and TPED were moderate (middle finger) to very good (ICC: 48.4%-98.6% and 45.0%-99.5%, respectively). Intra-observer agreement was slightly higher on average than inter-observer agreement. Overall, the intra- and inter-observer agreement in diagnosing DD, and determining the severity of flexion contracture is high. Also, the newly introduced variable area of nodules and cords has high intra- and inter-observer agreement, indicating that it is suitable to measure disease extent. Copyright © 2015 Elsevier Ltd. All rights reserved.

  12. Evidence for the 'good genes' model: association of MHC class II DRB alleles with ectoparasitism and reproductive state in the neotropical lesser bulldog bat, Noctilio albiventris.

    Directory of Open Access Journals (Sweden)

    Julia Schad

    Full Text Available The adaptive immune system has a major impact on parasite resistance and life history strategies. Immunological defence is costly both in terms of immediate activation and long-term maintenance. The 'good genes' model predicts that males with genotypes that promote a good disease resistance have the ability to allocate more resources to reproductive effort which favours the transmission of good alleles into future generations. Our study shows a correlation between immune gene constitution (Major Histocompatibility Complex, MHC class II DRB, ectoparasite loads (ticks and bat flies and the reproductive state in a neotropical bat, Noctilio albiventris. Infestation rates with ectoparasites were linked to specific Noal-DRB alleles, differed among roosts, increased with body size and co-varied with reproductive state particularly in males. Non-reproductive adult males were more infested with ectoparasites than reproductively active males, and they had more often an allele (Noal-DRB*02 associated with a higher tick infestation than reproductively active males or subadults. We conclude that the individual immune gene constitution affects ectoparasite susceptibility, and contributes to fitness relevant trade-offs in male N. albiventris as suggested by the 'good genes' model.

  13. Evidence for the 'good genes' model: association of MHC class II DRB alleles with ectoparasitism and reproductive state in the neotropical lesser bulldog bat, Noctilio albiventris.

    Science.gov (United States)

    Schad, Julia; Dechmann, Dina K N; Voigt, Christian C; Sommer, Simone

    2012-01-01

    The adaptive immune system has a major impact on parasite resistance and life history strategies. Immunological defence is costly both in terms of immediate activation and long-term maintenance. The 'good genes' model predicts that males with genotypes that promote a good disease resistance have the ability to allocate more resources to reproductive effort which favours the transmission of good alleles into future generations. Our study shows a correlation between immune gene constitution (Major Histocompatibility Complex, MHC class II DRB), ectoparasite loads (ticks and bat flies) and the reproductive state in a neotropical bat, Noctilio albiventris. Infestation rates with ectoparasites were linked to specific Noal-DRB alleles, differed among roosts, increased with body size and co-varied with reproductive state particularly in males. Non-reproductive adult males were more infested with ectoparasites than reproductively active males, and they had more often an allele (Noal-DRB*02) associated with a higher tick infestation than reproductively active males or subadults. We conclude that the individual immune gene constitution affects ectoparasite susceptibility, and contributes to fitness relevant trade-offs in male N. albiventris as suggested by the 'good genes' model.

  14. Agreement Theorems in Dynamic-Epistemic Logic

    NARCIS (Netherlands)

    Degremont, Cedric; Roy, Oliver

    2012-01-01

    This paper introduces Agreement Theorems to dynamic-epistemic logic. We show first that common belief of posteriors is sufficient for agreement in epistemic-plausibility models, under common and well-founded priors. We do not restrict ourselves to the finite case, showing that in countable structure

  15. Analyzing rater agreement manifest variable methods

    CERN Document Server

    von Eye, Alexander

    2014-01-01

    Agreement among raters is of great importance in many domains. For example, in medicine, diagnoses are often provided by more than one doctor to make sure the proposed treatment is optimal. In criminal trials, sentencing depends, among other things, on the complete agreement among the jurors. In observational studies, researchers increase reliability by examining discrepant ratings. This book is intended to help researchers statistically examine rater agreement by reviewing four different approaches to the technique.The first approach introduces readers to calculating coefficients that allow one to summarize agreements in a single score. The second approach involves estimating log-linear models that allow one to test specific hypotheses about the structure of a cross-classification of two or more raters'' judgments. The third approach explores cross-classifications or raters'' agreement for indicators of agreement or disagreement, and for indicators of such characteristics as trends. The fourth approach compa...

  16. Development of QSAR models for microsomal stability: identification of good and bad structural features for rat, human and mouse microsomal stability.

    Science.gov (United States)

    Hu, Yongbo; Unwalla, Ray; Denny, R Aldrin; Bikker, Jack; Di, Li; Humblet, Christine

    2010-01-01

    High throughput microsomal stability assays have been widely implemented in drug discovery and many companies have accumulated experimental measurements for thousands of compounds. Such datasets have been used to develop in silico models to predict metabolic stability and guide the selection of promising candidates for synthesis. This approach has proven most effective when selecting compounds from proposed virtual libraries prior to synthesis. However, these models are not easily interpretable at the structural level, and thus provide little insight to guide traditional synthetic efforts. We have developed global classification models of rat, mouse and human liver microsomal stability using in-house data. These models were built with FCFP_6 fingerprints using a Naïve Bayesian classifier within Pipeline Pilot. The test sets were correctly classified as stable or unstable with satisfying accuracies of 78, 77 and 75% for rat, human and mouse models, respectively. The prediction confidence was assigned using the Bayesian score to assess the applicability of the models. Using the resulting models, we developed a novel data mining strategy to identify structural features associated with good and bad microsomal stability. We also used this approach to identify structural features which are good for one species but bad for another. With these findings, the structure-metabolism relationships are likely to be understood faster and earlier in drug discovery.

  17. COMMD1-deficient dogs accumulate copper in hepatocytes and provide a good model for chronic hepatitis and fibrosis.

    Directory of Open Access Journals (Sweden)

    Robert P Favier

    Full Text Available New therapeutic concepts developed in rodent models should ideally be evaluated in large animal models prior to human clinical application. COMMD1-deficiency in dogs leads to hepatic copper accumulation and chronic hepatitis representing a Wilson's disease like phenotype. Detailed understanding of the pathogenesis and time course of this animal model is required to test its feasibility as a large animal model for chronic hepatitis. In addition to mouse models, true longitudinal studies are possible due to the size of these dogs permitting detailed analysis of the sequence of events from initial insult to final cirrhosis. Therefore, liver biopsies were taken each half year from five new born COMMD1-deficient dogs over a period of 42 months. Biopsies were used for H&E, reticulin, and rubeanic acid (copper staining. Immunohistochemistry was performed on hepatic stellate cell (HSC activation marker (alpha-smooth muscle actin, α-SMA, proliferation (Ki67, apoptosis (caspase-3, and bile duct and liver progenitor cell (LPC markers keratin (K 19 and 7. Quantitative RT-PCR and Western Blots were performed on gene products involved in the regenerative and fibrotic pathways. Maximum copper accumulation was reached at 12 months of age, which coincided with the first signs of hepatitis. HSCs were activated (α-SMA from 18 months onwards, with increasing reticulin deposition and hepatocytic proliferation in later stages. Hepatitis and caspase-3 activity (first noticed at 18 months increased over time. Both HGF and TGF-β1 gene expression peaked at 24 months, and thereafter decreased gradually. Both STAT3 and c-MET showed an increased time-dependent activation. Smad2/3 phosphorylation, indicative for fibrogenesis, was present at all time-points. COMMD1-deficient dogs develop chronic liver disease and cirrhosis comparable to human chronic hepatitis, although at much higher pace. Therefore they represent a genetically-defined large animal model to test clinical

  18. The Australia-US Free Trade Agreement: An Assessment

    OpenAIRE

    Philippa Dee

    2005-01-01

    Australia and the United States signed a bilateral trade agreement in 2004. This paper analyses the provisions of the agreement, compares the provisions with other bilateral and multilateral agreements and comments on the modelling that the Australian Government used to estimate the likely benefits of the agreement. The author concludes that the modelling relied on overstates the potential gains from the agreement, which establishes many undesirable precedents, especially in relation to sugar...

  19. Valuing spatially dispersed environmental goods: A joint revealed and stated preference model to consistently separate use and non-use values

    OpenAIRE

    FERRINI, Silvia; Fezzi, Carlo; Day, Brett H.; BATEMAN, Ian J.

    2008-01-01

    We argue that the literature concerning the valuation of non-market, spatially defined goods (such as those provided by the natural environment) is crucially deficient in two respects. First, it fails to employ a theoretically consistent structural model of utility to the separate and hence correct definition of use and non-use values. Second, applications (particularly those using stated preference methods) typically fail to capture the spatially complex distribution of resources and their s...

  20. 四川省社会消费品零售额的ARIMA预测模型%ARIMA Prediction Model on Retail Sales of Consumer Goods in Sichuan

    Institute of Scientific and Technical Information of China (English)

    陈龙; 马亮亮; 刘冬兵

    2012-01-01

    Based on analyzing monthly total sales of consumer goods from 2008 to 2009 in Sichuan Province,China,the author tries to set up ARIMA model.The model's forecasting ability has been measured by MAPE(mean absolute percent error).Secondly,this paper forecasts monthly total sales of consumer goods of 2010 in Sichuan,and compares the predictive value and the actual value.The result indicates that the model provides an excellent forecasting,and the model is fit for forecasting the total sales of consumer goods in Sichuan.Last,some corresponding policy advices have been put forward.%通过分析四川省2008年至2009年每月的社会消费品零售额,建立了ARIMA模型。借助于MAPE(平均绝对百分比误差)度量了模型的预测能力。其次,文章利用所建模型对四川省2010年每月的社会消费品零售额进行预测,并与其实际值进行比较。结果表明,模型的预测精确度非常高,适合于四川省社会消费品零售额的预测。最后,提出了一些相应的政策建议。

  1. Asymptotics of the goodness-of-fit test for a partial linear model with randomly censored data

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    In this paper, we discuss the problem of testing the hypothesis that the underlying regression isa partial linear model. A test statistic, which is based on the quadratic form of a cusum process of residuals,is proposed. The asymptotic distributions of the test statistic under null hypothesis and the local alternativehypothesis are given. The number simulation shows that the test is available.

  2. Limited-Information Goodness-of-Fit Testing of Diagnostic Classification Item Response Theory Models. CRESST Report 840

    Science.gov (United States)

    Hansen, Mark; Cai, Li; Monroe, Scott; Li, Zhen

    2014-01-01

    It is a well-known problem in testing the fit of models to multinomial data that the full underlying contingency table will inevitably be sparse for tests of reasonable length and for realistic sample sizes. Under such conditions, full-information test statistics such as Pearson's X[superscript 2]?? and the likelihood ratio statistic…

  3. The relational model is dead, SQL is dead, and i don't feel so good myself

    DEFF Research Database (Denmark)

    Atzeni, Paolo; Jensen, Christian S .; Orsi, Giorgio;

    2013-01-01

    We report the opinions expressed by well-known database researchers on the future of the relational model and SQL during a panel at the International Workshop on Non-Conventional Data Access (NoCoDa 2012), held in Florence, Italy in October 2012 in conjunction with the 31st International Conferen...

  4. What Makes a Good Feature?

    Science.gov (United States)

    1992-04-01

    model to 3 RICHARDS & JEPSON WHAT MAKES A GOOD FEATURE? distinguish between good and bad features, and whether the world needs to satisfy this...A MASSACHUSETTS INSTITUTE OF TECHNOLOGY 0ARTIFICIAL INTELLIGENCE LABORATORY - and "-- CENTER FOR BIOLOGICAL INFORMATION PROCESSING Lfl • •C AI. Memo...No. 1356 April 1992 S C.B.I.P. Paper No. 72 D T IC OWhat Makes a Good Feature? ELECTESJAN 2 9 19931 W. Richards and A. Jepson S c i Abstract

  5. 'Too much good news' - are Alzheimer mouse models trying to tell us how to prevent, not cure, Alzheimer's disease?

    Science.gov (United States)

    Zahs, Kathleen R; Ashe, Karen H

    2010-08-01

    Scores of compounds ameliorate cognitive deficits or neuropathology in transgenic mouse models of Alzheimer's disease (AD), yet these triumphs in mice have not translated into successful therapies for people. Why have studies in mice failed to predict results of human trials? We argue that most transgenic mouse 'models of AD' actually simulate the asymptomatic phase of the disease, and the results of interventional studies in these mice should be considered in the context of disease prevention. In addition, recent advances in imaging technology and biomarker discovery should aid in comparisons of mouse and human neurological status and, importantly, might allow us to predict better the response of people to drugs tested in mice. Copyright 2010. Published by Elsevier Ltd.

  6. “Space, the Final Frontier”: How Good are Agent-Based Models at Simulating Individuals and Space in Cities?

    Directory of Open Access Journals (Sweden)

    Alison Heppenstall

    2016-01-01

    Full Text Available Cities are complex systems, comprising of many interacting parts. How we simulate and understand causality in urban systems is continually evolving. Over the last decade the agent-based modeling (ABM paradigm has provided a new lens for understanding the effects of interactions of individuals and how through such interactions macro structures emerge, both in the social and physical environment of cities. However, such a paradigm has been hindered due to computational power and a lack of large fine scale datasets. Within the last few years we have witnessed a massive increase in computational processing power and storage, combined with the onset of Big Data. Today geographers find themselves in a data rich era. We now have access to a variety of data sources (e.g., social media, mobile phone data, etc. that tells us how, and when, individuals are using urban spaces. These data raise several questions: can we effectively use them to understand and model cities as complex entities? How well have ABM approaches lent themselves to simulating the dynamics of urban processes? What has been, or will be, the influence of Big Data on increasing our ability to understand and simulate cities? What is the appropriate level of spatial analysis and time frame to model urban phenomena? Within this paper we discuss these questions using several examples of ABM applied to urban geography to begin a dialogue about the utility of ABM for urban modeling. The arguments that the paper raises are applicable across the wider research environment where researchers are considering using this approach.

  7. How good are the simulations of tropical SST–rainfall relationship by IPCC AR4 atmospheric and coupled models?

    Indian Academy of Sciences (India)

    K Rajendran; Ravi S Nanjundiah; Sulochana Gadgil; J Srinivasan

    2012-06-01

    The failure of atmospheric general circulation models (AGCMs) forced by prescribed SST to simulate and predict the interannual variability of Indian/Asian monsoon has been widely attributed to their inability to reproduce the actual sea surface temperature (SST)–rainfall relationship in the warm Indo-Pacific oceans. This assessment is based on a comparison of the observed and simulated correlation between the rainfall and local SST. However, the observed SSTconvection/rainfall relationship is nonlinear and for this a linear measure such as the correlation is not an appropriate measure. We show that the SST–rainfall relationship simulated by atmospheric and coupled general circulation models in IPCC AR4 is nonlinear, as observed, and realistic over the tropical West Pacific (WPO) and the Indian Ocean (IO). The SST–rainfall pattern simulated by the coupled versions of these models is rather similar to that from the corresponding atmospheric one, except for a shift of the entire pattern to colder/warmer SSTs when there is a cold/warm bias in the coupled version.

  8. Model and Algorithm for Optimal Allocation of Mix-loading Goods%混装货物优化配置模型及算法

    Institute of Scientific and Technical Information of China (English)

    俞武扬

    2012-01-01

    This paper presents an optimal allocation model of mix-loading goods to minimize the total freight. Mix-loading of different goods with different transportation rate, gross weight and volume is the basis of this optimal allocation model. By using two relative lemmas, it proposes a heuristic algorithm to solve this model. Numerical examples are presented to demonstrate the efficiencies of the heuristic algorithm by comparing with a basic Genetic Algorithm(GA). Giving 10 groups random data of 50 piece goods, experimental results show that the average runtime of GA is 2 325 times as much as that of heuristic algorithm, and give 10 groups random data of 200 piece goods, the average runtime of heuristic algorithm is only 4.009 4 s.%为最小化总运费,提出一种混装货物的优化配置模型.根据不同货物的运输费率、实际重量和体积重量完成混装搭配,在证明2个相关引理的基础上设计启发式算法,将其与基本遗传算法进行多组随机计算比较.实验结果表明,对于50件货物的10组随机数据,遗传算法所用平均计算时间是启发式算法的2 325倍,对于200件物品的10组随机数据,启发式算法所用的平均计算时间仅为4.0094s.

  9. Individual differences and the characterization of animal models of psychopathology: a strong challenge and a good opportunity

    Directory of Open Access Journals (Sweden)

    Antonio eArmario

    2013-11-01

    Full Text Available Despite the development of valuable new techniques (i.e. genetics, neuroimage for the study of the neurobiological substrate of psychiatric diseases, there are strong limitations in the information that can be gathered from human studies. It is thus critical to develop appropriate animal models of psychiatric diseases to characterize their putative biological bases and the development of new therapeutic strategies. The present review tries to offer a general perspective and several examples of how individual differences in animals can contribute to explain differential susceptibility to develop behavioural alterations, but also emphasizes methodological problems that can lead to inappropriate or over-simplistic interpretations. A critical analysis of the approaches currently used could contribute to obtain more reliable data and allow taking full advantage of new and sophisticated technologies. The discussion is mainly focused on anxiety-like and to a lower extent on depression-like behaviour in rodents.

  10. Score, pseudo-score and residual diagnostics for goodness-of-fit of spatial point process models

    DEFF Research Database (Denmark)

    Baddeley, Adrian; Rubak, Ege Holger; Møller, Jesper

    We develop newtools for formal inference and informalmodel validation in the analysis of spatial point pattern data. The score test is generalised to a ‘pseudo-score’ test derived from Besag’s pseudolikelihood, and to a class of diagnostics based on point process residuals. The results lend...... theoretical support to the established practice of using functional summary statistics such as Ripley’s K-function, when testing for complete spatial randomness; and they provide new tools such as the compensator of the K-function for testing other fitted models. The results also support localisation methods...... such as the scan statistic and smoothed residual plots. Software for computing the diagnostics is provided....

  11. Are Sema5a mutant mice a good model of autism? A behavioral analysis of sensory systems, emotionality and cognition.

    Science.gov (United States)

    Gunn, Rhian K; Huentelman, Matthew J; Brown, Richard E

    2011-11-20

    Semaphorin 5A (Sema5A) expression is reduced in the brain of individuals with autism, thus mice with reduced Sema5A levels may serve as a model of this neurodevelopmental disorder. We tested male and female Sema5a knockout mice (B6.129P2SEMA5A()/J) and C57BL/6J controls for emotionality, visual ability, prepulse inhibition, motor learning and cognition. Overall, there were only two genotype differences in emotionality: Sema5a mutant mice had more stretch-attend postures in the elevated plus-maze and more defecations in the open field. All mice could see, but Sema5a mice had better visual ability than C57BL/6J mice. There were no genotype differences in sensory-motor gating. Sema5a mice showed higher levels of activity in the elevated plus-maze and light/dark transition box, and there were sex by genotype differences in the Rotarod, suggesting a sex difference in balance and coordination differentially affected by Sema5a. There were no genotype effects on cognition: Sema5a mice did not differ from C57BL/6J in the Morris water maze, set-shifting or cued and contextual fear conditioning. In the social recognition test, all mice preferred social stimuli, but there was no preference for social novelty, thus the Sema5A mice do not have a deficit in social behavior. Overall, there were a number of sex differences, with females showing greater activity and males performing better in tests of spatial learning and memory, but no deficits in the behavior of Sema5A mice. We conclude that the Sema5a mice do not meet the behavioral criteria for a mouse model of autism. Copyright © 2011 Elsevier B.V. All rights reserved.

  12. Does the macaque monkey provide a good model for studying human executive control? A comparative behavioral study of task switching.

    Directory of Open Access Journals (Sweden)

    Luana Caselli

    Full Text Available The ability to swiftly and smoothly switch from one task set to another is central to intelligent behavior, because it allows an organism to flexibly adapt to ever changing environmental conditions and internal needs. For this reason, researchers interested in executive control processes have often relied on task-switching paradigms as powerful tools to uncover the underlying cognitive and brain architecture. In order to gather fundamental information at the single-cell level, it would be greatly helpful to demonstrate that non-human primates, especially the macaque monkey, share with us similar behavioral manifestations of task-switching and therefore, in all likelihood, similar underlying brain mechanisms. Unfortunately, prior attempts have provided negative results (e.g., Stoet & Snyder, 2003b, in that it was reported that macaques do not show the typical signature of task-switching operations at the behavioral level, represented by switch costs. If confirmed, this would indicate that the macaque cannot be used as a model approach to explore human executive control mechanisms by means of task-switching paradigms. We have therefore decided to re-explore this issue, by conducting a comparative experiment on a group of human participants and two macaque monkeys, whereby we measured and compared performance costs linked to task switching and resistance to interference across the two species. Contrary to what previously reported, we found that both species display robust task switching costs, thus supporting the claim that macaque monkeys provide an exquisitely suitable model to study the brain mechanisms responsible for maintaining and switching task sets.

  13. Does the macaque monkey provide a good model for studying human executive control? A comparative behavioral study of task switching.

    Science.gov (United States)

    Caselli, Luana; Chelazzi, Leonardo

    2011-01-01

    The ability to swiftly and smoothly switch from one task set to another is central to intelligent behavior, because it allows an organism to flexibly adapt to ever changing environmental conditions and internal needs. For this reason, researchers interested in executive control processes have often relied on task-switching paradigms as powerful tools to uncover the underlying cognitive and brain architecture. In order to gather fundamental information at the single-cell level, it would be greatly helpful to demonstrate that non-human primates, especially the macaque monkey, share with us similar behavioral manifestations of task-switching and therefore, in all likelihood, similar underlying brain mechanisms. Unfortunately, prior attempts have provided negative results (e.g., Stoet & Snyder, 2003b), in that it was reported that macaques do not show the typical signature of task-switching operations at the behavioral level, represented by switch costs. If confirmed, this would indicate that the macaque cannot be used as a model approach to explore human executive control mechanisms by means of task-switching paradigms. We have therefore decided to re-explore this issue, by conducting a comparative experiment on a group of human participants and two macaque monkeys, whereby we measured and compared performance costs linked to task switching and resistance to interference across the two species. Contrary to what previously reported, we found that both species display robust task switching costs, thus supporting the claim that macaque monkeys provide an exquisitely suitable model to study the brain mechanisms responsible for maintaining and switching task sets.

  14. Developing and Optimising the Use of Logic Models in Systematic Reviews: Exploring Practice and Good Practice in the Use of Programme Theory in Reviews.

    Science.gov (United States)

    Kneale, Dylan; Thomas, James; Harris, Katherine

    2015-01-01

    Logic models are becoming an increasingly common feature of systematic reviews, as is the use of programme theory more generally in systematic reviewing. Logic models offer a framework to help reviewers to 'think' conceptually at various points during the review, and can be a useful tool in defining study inclusion and exclusion criteria, guiding the search strategy, identifying relevant outcomes, identifying mediating and moderating factors, and communicating review findings. In this paper we critique the use of logic models in systematic reviews and protocols drawn from two databases representing reviews of health interventions and international development interventions. Programme theory featured only in a minority of the reviews and protocols included. Despite drawing from different disciplinary traditions, reviews and protocols from both sources shared several limitations in their use of logic models and theories of change, and these were used almost unanimously to solely depict pictorially the way in which the intervention worked. Logic models and theories of change were consequently rarely used to communicate the findings of the review. Logic models have the potential to be an aid integral throughout the systematic reviewing process. The absence of good practice around their use and development may be one reason for the apparent limited utility of logic models in many existing systematic reviews. These concerns are addressed in the second half of this paper, where we offer a set of principles in the use of logic models and an example of how we constructed a logic model for a review of school-based asthma interventions.

  15. Does Breast Cancer Drive the Building of Survival Probability Models among States? An Assessment of Goodness of Fit for Patient Data from SEER Registries

    Science.gov (United States)

    Khan, Hafiz; Saxena, Anshul; Perisetti, Abhilash; Rafiq, Aamrin; Gabbidon, Kemesha; Mende, Sarah; Lyuksyutova, Maria; Quesada, Kandi; Blakely, Summre; Torres, Tiffany; Afesse, Mahlet

    2016-12-01

    Background: Breast cancer is a worldwide public health concern and is the most prevalent type of cancer in women in the United States. This study concerned the best fit of statistical probability models on the basis of survival times for nine state cancer registries: California, Connecticut, Georgia, Hawaii, Iowa, Michigan, New Mexico, Utah, and Washington. Materials and Methods: A probability random sampling method was applied to select and extract records of 2,000 breast cancer patients from the Surveillance Epidemiology and End Results (SEER) database for each of the nine state cancer registries used in this study. EasyFit software was utilized to identify the best probability models by using goodness of fit tests, and to estimate parameters for various statistical probability distributions that fit survival data. Results: Statistical analysis for the summary of statistics is reported for each of the states for the years 1973 to 2012. Kolmogorov-Smirnov, Anderson-Darling, and Chi-squared goodness of fit test values were used for survival data, the highest values of goodness of fit statistics being considered indicative of the best fit survival model for each state. Conclusions: It was found that California, Connecticut, Georgia, Iowa, New Mexico, and Washington followed the Burr probability distribution, while the Dagum probability distribution gave the best fit for Michigan and Utah, and Hawaii followed the Gamma probability distribution. These findings highlight differences between states through selected sociodemographic variables and also demonstrate probability modeling differences in breast cancer survival times. The results of this study can be used to guide healthcare providers and researchers for further investigations into social and environmental factors in order to reduce the occurrence of and mortality due to breast cancer. Creative Commons Attribution License

  16. Pricing strategies for information goods

    Indian Academy of Sciences (India)

    Siva Viswanathan; G Anandalingam

    2005-04-01

    Digital or information goods are becoming the norm across a wide variety of industries including books, music, entertainment, gaming and education. Due to the fact that the marginal cost of producing or reproducing information goods is very low, it is much easier to customise and personalise them for individual users. Furthermore, sellers of these information goods are increasingly using bundling and versioning strategies to appropriate a greater share of the surplus. This paper examines recent research on pricing of information goods with particular focus on customisation, bundling and versioning strategies adopted by information goods providers. The paper highlights both game-theoretic as well as optimisation models that not only provide different perspectives, but also examine issues of information goods pricing at different levels of abstraction and complexity.

  17. Predicative Adjective Agreement

    DEFF Research Database (Denmark)

    Vikner, Sten

    2001-01-01

    German is a complicated language. Any speaker of e.g. French or Danish who has ever tried to learn German would agree to this. Coming from languages with only two genders and with no case outside the pronoun system, German, with three genders and with four cases throughout the nominal system, seems...... unjustifiably complicated, as if it had been specially designed to torment poor students. However, there is one area where German agreement morphology could not possibly be simpler, and where German is much easier for non-native speakers than e.g. French or Danish: predicative adjectives. Both gender and number...... distinctions, disappear when adjectives are used predicatively. This paper will try to account for why the Germanic languages that inflect attiributive adjectives but not predicative ones are all SOV-languages (e.g. German, Dutch, Frisian and Yiddish)....

  18. Bayesian methods for measures of agreement

    CERN Document Server

    Broemeling, Lyle D

    2009-01-01

    Using WinBUGS to implement Bayesian inferences of estimation and testing hypotheses, Bayesian Methods for Measures of Agreement presents useful methods for the design and analysis of agreement studies. It focuses on agreement among the various players in the diagnostic process.The author employs a Bayesian approach to provide statistical inferences based on various models of intra- and interrater agreement. He presents many examples that illustrate the Bayesian mode of reasoning and explains elements of a Bayesian application, including prior information, experimental information, the likelihood function, posterior distribution, and predictive distribution. The appendices provide the necessary theoretical foundation to understand Bayesian methods as well as introduce the fundamentals of programming and executing the WinBUGS software.Taking a Bayesian approach to inference, this hands-on book explores numerous measures of agreement, including the Kappa coefficient, the G coefficient, and intraclass correlation...

  19. The EU-Turkey March 2016 Agreement As a Model: New Refugee Regimes and Practices in the Arab Mediterranean and the Case of Libya

    DEFF Research Database (Denmark)

    Seeberg, Peter

    2016-01-01

    to the Arab Mediterranean and more specifically in the context of Libya, as and when political and security conditions in that country improve. The author recognizes that despite relevant criticism of the EU-Turkey deal, the agreement may well contain building blocks worth taking into consideration in future...

  20. Is the Polder Model Good for the Economy?: A New Interpretation of Dutch Economic and Social History

    Directory of Open Access Journals (Sweden)

    Karel Davids

    2014-03-01

    Full Text Available The book Nederland en het poldermodel [The Netherlands and the Polder Model] is a commendable effort to present a new, theory-informed interpretation of the economic and social history of the Netherlands of the last thousand years. However, this review questions the supposed causal relationship between civil society (‘polder model’ and economic growth. The authors assume that economic growth emanates from a vibrant civil society and that likewise economic decline coincides with a weakening of civil society. Upon closer inspection however, their concepts seem to be imperfectly related to the theories they claim to use as inspiration. Thesupposed waning of civil society after 1670 and after 1815 is not substantiated by historical facts either. Their thesis would have benefited greatly from a comparative analysis, both spatially and in time. The rather haphazard use of the term ‘civil society’ precludes convincing conclusions over time, while an international perspective is lacking altogether – a sadly missed opportunity.Is het poldermodel goed voor de economie? Een nieuwe interpretatie van de Nederlandse economische en sociale geschiedenisHet boek Nederland en het poldermodel is een lovenswaardige poging om een nieuwe, op theoretische basis geschoeide interpretatie van de sociale en economische geschiedenis van Nederland van de laatste duizend jaar te presenteren. Deze bijdrage stelt echter vragen bij het veronderstelde causale verband tussen ‘civil society’ (het poldermodel en economische groei. De auteurs nemen aan dat economische groei optreedt als een civil society sterk is en dat omgekeerd economisch verval zich voordoet als een civil society verzwakt. Bij nader inzien blijken hun concepten niet goed te sporen met de theorieën die hen tot inspiratie dienen. De veronderstelde kwijnende civil society na 1670 en na 1815 is ook niet op historische feiten gebaseerd. Hun stelling zou aan kracht hebben gewonnen indien zij een

  1. 19 CFR 10.771 - Textile or apparel goods.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Textile or apparel goods. 10.771 Section 10.771... Agreement Rules of Origin § 10.771 Textile or apparel goods. (a) De minimis. Except as provided in paragraph (a)(1) of this section, a textile or apparel good that is not an originating good under the...

  2. 19 CFR 10.811 - Textile or apparel goods.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Textile or apparel goods. 10.811 Section 10.811... Agreement Rules of Origin § 10.811 Textile or apparel goods. (a) De minimis—(1) General. Except as provided in paragraph (a)(2) of this section, a textile or apparel good that is not an originating good...

  3. VHA Data Sharing Agreement Repository

    Data.gov (United States)

    Department of Veterans Affairs — The VHA Data Sharing Agreement Repository serves as a centralized location to collect and report on agreements that share VHA data with entities outside of VA. It...

  4. Developing and Optimising the Use of Logic Models in Systematic Reviews: Exploring Practice and Good Practice in the Use of Programme Theory in Reviews

    Science.gov (United States)

    Kneale, Dylan; Thomas, James; Harris, Katherine

    2015-01-01

    Background Logic models are becoming an increasingly common feature of systematic reviews, as is the use of programme theory more generally in systematic reviewing. Logic models offer a framework to help reviewers to ‘think’ conceptually at various points during the review, and can be a useful tool in defining study inclusion and exclusion criteria, guiding the search strategy, identifying relevant outcomes, identifying mediating and moderating factors, and communicating review findings. Methods and Findings In this paper we critique the use of logic models in systematic reviews and protocols drawn from two databases representing reviews of health interventions and international development interventions. Programme theory featured only in a minority of the reviews and protocols included. Despite drawing from different disciplinary traditions, reviews and protocols from both sources shared several limitations in their use of logic models and theories of change, and these were used almost unanimously to solely depict pictorially the way in which the intervention worked. Logic models and theories of change were consequently rarely used to communicate the findings of the review. Conclusions Logic models have the potential to be an aid integral throughout the systematic reviewing process. The absence of good practice around their use and development may be one reason for the apparent limited utility of logic models in many existing systematic reviews. These concerns are addressed in the second half of this paper, where we offer a set of principles in the use of logic models and an example of how we constructed a logic model for a review of school-based asthma interventions. PMID:26575182

  5. 76 FR 68067 - United States-Peru Trade Promotion Agreement

    Science.gov (United States)

    2011-11-03

    ... to trade in textile and apparel goods between Peru and the United States. The provisions within...] RIN 1515-AD79 United States-Peru Trade Promotion Agreement AGENCIES: U.S. Customs and Border... of the United States- Peru Trade Promotion Agreement. DATES: Interim rule effective November 3, 2011...

  6. Service offerings and agreements a guide for ITIL exam candidates

    CERN Document Server

    Griffiths, Richard

    2014-01-01

    By implementing good practice in service offerings and agreements, IT departments can achieve customer satisfaction. Providing clarification and expansion of the core ITIL® texts, this new edition reflects the current thinking from ITIL and is aligned to the latest syllabus for the Intermediate Certificate in Service Offerings and Agreements.

  7. Service offerings and agreements a guide for ITIL exam candidates

    CERN Document Server

    Griffiths, Richard

    2014-01-01

    By implementing good practice in service offerings and agreements, IT departments can achieve customer satisfaction. Providing clarification and expansion of the core ITIL® texts, this new edition reflects the current thinking from ITIL and is aligned to the latest syllabus for the Intermediate Certificate in Service Offerings and Agreements.

  8. Agreement with Subjects in Lubukusu

    Science.gov (United States)

    Diercks, Michael J. K.

    2010-01-01

    This dissertation examines three topics in the morphosyntax of Lubukusu (Bantu, Kenya), all of which are concerned with agreement with subjects: locative inversion, complementizer agreement, and alternative agreement effects in subject extraction. Each topic reports novel Lubukusu data which are both typologically interesting and theoretically…

  9. Good Concrete Activity Is Good Mental Activity

    Science.gov (United States)

    McDonough, Andrea

    2016-01-01

    Early years mathematics classrooms can be colourful, exciting, and challenging places of learning. Andrea McDonough and fellow teachers have noticed that some students make good decisions about using materials to assist their problem solving, but this is not always the case. These experiences lead her to ask the following questions: (1) Are…

  10. Predicting word sense annotation agreement

    DEFF Research Database (Denmark)

    Martinez Alonso, Hector; Johannsen, Anders Trærup; Lopez de Lacalle, Oier

    2015-01-01

    High agreement is a common objective when annotating data for word senses. However, a number of factors make perfect agreement impossible, e.g. the limitations of the sense inventories, the difficulty of the examples or the interpretation preferences of the annotations. Estimating potential...... agreement is thus a relevant task to supplement the evaluation of sense annotations. In this article we propose two methods to predict agreement on word-annotation instances. We experiment with a continuous representation and a three-way discretization of observed agreement. In spite of the difficulty...

  11. REVIEW OF THE NEGOTIATION OF THE MODEL PROTOCOL ADDITIONAL TO THE AGREEMENT(S) BETWEEN STATE(S) AND THE INTERNATIONAL ATOMIC ENERGY AGENCY FOR THE APPLICATION OF SAFEGUARDS, INFCIRC/540 (Corrected) VOLUME II/III IAEA COMMITTEE 24, Major Issues Underlying the Model Additional Protocol (1996-1997).

    Energy Technology Data Exchange (ETDEWEB)

    Rosenthal, M.D.; Saum-Manning, L.; Houck, F.

    2010-01-01

    Volume I of this Review traces the origins of the Model Additional Protocol. It covers the period from 1991, when events in Iraq triggered an intensive review of the safeguards system, until 1996, when the IAEA Board of Governors established Committee 24 to negotiate a new protocol to safeguards agreement. The period from 1991-1996 set the stage for this negotiation and shaped its outcome in important ways. During this 5-year period, many proposals for strengthening safeguards were suggested and reviewed. Some proposals were dropped, for example, the suggestion by the IAEA Secretariat to verify certain imports, and others were refined. A rough consensus was established about the directions in which the international community wanted to go, and this was reflected in the draft of an additional protocol that was submitted to the IAEA Board of Governors on May 6, 1996 in document GOV/2863, Strengthening the Effectiveness and Improving the Efficiency of the Safeguards System - Proposals For Implementation Under Complementary Legal Authority, A Report by the Director General. This document ended with a recommendation that, 'the Board, through an appropriate mechanism, finalize the required legal instrument taking as a basis the draft protocol proposed by the Secretariat and the explanation of the measures contained in this document.'

  12. 高校校园二手物品交易新模式的探究%The New Model of Second-Hand Goods Trading at Universities

    Institute of Scientific and Technical Information of China (English)

    孟惊雷; 王蕊

    2013-01-01

    随着可持续发展的经济改革进一步深化,资源节约和再利用的观念受到大学生群体的广泛认可。在高校校园里推行二手物品的交易新模式对于资源的节约和再利用具有积极意义。高校校园二手物品交易新模式的设计方案,主要包括平台的价值定位、运营模式、推广方法等内容。为了让广大师生尽快接受校园二手物品交易网站,需要不断进行宣传和引导,以增加网站的知名度和影响力。%With the further deepening of sustainable economic reform, the concept of resource conservation and reuse is widely recognized by college students. On university campuses, it is significant to popularize new model of second-hand goods trading at college campuses for resource conservation and reuse. The designs of the new model include the value proposition of the platform, operating model and mar-keting method. In order to have teachers and students acknowledge second-hand goods trading sites as soon as possible and increase the popularity and influence of the sites, constant dissemination is necessary.

  13. A Model for Good Governance of Healthcare Technology Management in the Public Sector: Learning from Evidence-Informed Policy Development and Implementation in Benin

    Science.gov (United States)

    Houngbo, P. Th.; Zweekhorst, M.; De Cock Buning, Tj.; Medenou, D.; Bunders, J. F. G.

    2017-01-01

    Good governance (GG) is an important concept that has evolved as a set of normative principles for low- and middle-income countries (LMICs) to strengthen the functional capacity of their public bodies, and as a conditional prerequisite to receive donor funding. Although much is written on good governance, very little is known on how to implement it. This paper documents the process of developing a strategy to implement a GG model for Health Technology Management (HTM) in the public health sector, based on lessons learned from twenty years of experience in policy development and implementation in Benin. The model comprises six phases: (i) preparatory analysis, assessing the effects of previous policies and characterizing the HTM system; (ii) stakeholder identification and problem analysis, making explicit the perceptions of problems by a diverse range of actors, and assessing their ability to solve these problems; (iii) shared analysis and visioning, delineating the root causes of problems and hypothesizing solutions; (iv) development of policy instruments for pilot testing, based on quick-win solutions to understand the system’s responses to change; (v) policy development and validation, translating the consensus solutions identified by stakeholders into a policy; and (vi) policy implementation and evaluation, implementing the policy through a cycle of planning, action, observation and reflection. The policy development process can be characterized as bottom-up, with a central focus on the participation of diverse stakeholders groups. Interactive and analytical tools of action research were used to integrate knowledge amongst actor groups, identify consensus solutions and develop the policy in a way that satisfies criteria of GG. This model could be useful for other LMICs where resources are constrained and the majority of healthcare technologies are imported. PMID:28056098

  14. A Model for Good Governance of Healthcare Technology Management in the Public Sector: Learning from Evidence-Informed Policy Development and Implementation in Benin.

    Science.gov (United States)

    Houngbo, P Th; Coleman, H L S; Zweekhorst, M; De Cock Buning, Tj; Medenou, D; Bunders, J F G

    2017-01-01

    Good governance (GG) is an important concept that has evolved as a set of normative principles for low- and middle-income countries (LMICs) to strengthen the functional capacity of their public bodies, and as a conditional prerequisite to receive donor funding. Although much is written on good governance, very little is known on how to implement it. This paper documents the process of developing a strategy to implement a GG model for Health Technology Management (HTM) in the public health sector, based on lessons learned from twenty years of experience in policy development and implementation in Benin. The model comprises six phases: (i) preparatory analysis, assessing the effects of previous policies and characterizing the HTM system; (ii) stakeholder identification and problem analysis, making explicit the perceptions of problems by a diverse range of actors, and assessing their ability to solve these problems; (iii) shared analysis and visioning, delineating the root causes of problems and hypothesizing solutions; (iv) development of policy instruments for pilot testing, based on quick-win solutions to understand the system's responses to change; (v) policy development and validation, translating the consensus solutions identified by stakeholders into a policy; and (vi) policy implementation and evaluation, implementing the policy through a cycle of planning, action, observation and reflection. The policy development process can be characterized as bottom-up, with a central focus on the participation of diverse stakeholders groups. Interactive and analytical tools of action research were used to integrate knowledge amongst actor groups, identify consensus solutions and develop the policy in a way that satisfies criteria of GG. This model could be useful for other LMICs where resources are constrained and the majority of healthcare technologies are imported.

  15. REVIEW OF THE NEGOTIATION OF THE MODEL PROTOCOL ADDITIONAL TO THE AGREEMENT(S) BETWEEN STATE(S) AND THE INTERNATIONAL ATOMIC ENERGY AGENCY FOR THE APPLICATION OF SAFEGUARDS,INFCIRC/540 (Corrected) VOLUME I/III SETTING THE STAGE: 1991-1996.

    Energy Technology Data Exchange (ETDEWEB)

    Rosenthal, M.D.; Saum-Manning, L.; Houck, F.; Anzelon, G.

    2010-01-01

    Events in Iraq at the beginning of the 1990s demonstrated that the safeguards system of the International Atomic Energy Agency (IAEA) needed to be improved. It had failed, after all, to detect Iraq's clandestine nuclear weapon program even though some of Iraq's's activities had been pursued at inspected facilities in buildings adjacent to ones being inspected by the IAEA. Although there were aspects of the implementation of safeguards where the IAEA needed to improve, the primary limitations were considered to be part of the safeguards system itself. That system was based on the Nuclear Nonproliferation Treaty of 1970, to which Iraq was a party, and implemented on the basis of a model NPT safeguards agreement, published by the IAEA 1972 as INFCIRC/153 (corrected). The agreement calls for states to accept and for the IAEA to apply safeguards to all nuclear material in the state. Iraq was a party to such an agreement, but it violated the agreement by concealing nuclear material and other nuclear activities from the IAEA. Although the IAEA was inspecting in Iraq, it was hindered by aspects of the agreement that essentially limited its access to points in declared facilities and provided the IAEA with little information about nuclear activities anywhere else in Iraq. As a result, a major review of the NPT safeguards system was initiated by its Director General and Member States with the objective of finding the best means to enable the IAEA to detect both diversions from declared stocks and any undeclared nuclear material or activities in the state. Significant improvements that could be made within existing legal authority were taken quickly, most importantly a change in 1992 in how and when and what design information would be reported to the IAEA. During 1991-1996, the IAEA pursued intensive study, legal and technical analysis, and field trials and held numerous consultations with Member States. The Board of Governors discussed the issue of

  16. Is the mouse follicle culture a good model for the goat with respect to the development of preantral follicles in vitro?

    Science.gov (United States)

    Rocha, R M P; Alves, A M C V; Lima, L F; Duarte, A B G; Chaves, R N; Brito, I R; Costa, E C; Bernuci, M P; Rosa-e-Silva, A C J S; Xu, M; Rodrigues, A P R; Campello, C C; Figueiredo, J R

    2014-10-01

    The present study evaluated the efficiency of using 2 culture media developed for mice and for goats in the in vitro preantral follicle culture of each species. Murine and caprine secondary follicles were cultured in vitro with human recombinant follicle-stimulating hormone (murine medium) or with bovine recombinant follicle-stimulating hormone in association with growth hormone (caprine medium). The results showed that murine follicles cultured in caprine medium had lower (P 0.05). After in vitro maturation, a higher (P cultured under the same in vitro culture medium conditions respond differently; caprine oocytes grown in vitro in the presence of the murine medium show the greatest developmental competence among the tested combinations. Therefore, under the present experimental conditions, the mouse follicle culture has proved be a good model for the development of new culture media for caprine preantral follicles.

  17. Ocean Color Products Supporting the Assessment of Good Environmental Status: Development of a Spatial Distribution Model for the Seagrass Posidonia Oceanica (L.) Delille, 1813

    Science.gov (United States)

    Zucchetta, M.; Taji, M. A.; Mangin, A.; Pastres, R.

    2015-12-01

    Posidonia oceanica (L.) Delile, 1813 is a seagrass species endemic to the Mediterranean Sea, which is considered as one of the key habitats of the coastal areas. This species forms large meadows sensitive to several anthropogenic pressures, that can be regarded as indicators of environment quality in coastal environments and its distributional patterns should be take into account when evaluating the Environmental Status following the Ecosystem approach promoted by the Mediterranean Action Plan of UNEP and the EU Marine Strategy Framework Directive (2008/56/EC). The aim of this study was to develop a Species Distribution Model for P. oceanica, to be applied to the whole Mediterranean North African coast, in order to obtain an estimation of the potential distribution of this species in the region to be considered as an indicator for the assessment of good Environmental Status. As the study area is a data-poor zone with regard to seagrass distribution (i.e. only for some areas detailed distribution maps are available), the Species Distribution Model (SDM) was calibrated using high resolution data from 5 Mediterranean sites, located in Italy and Spain and validated using available data from the North African coast. Usually, when developing SDMs species occupancy data is available at coarser resolution than the information of environmental variables, and thus has to be downscaled at the appropriate grain to be coupled to the environmental conditions. Tackling the case of P. oceanica we had to face the opposite problem: the quality (in terms of resolution) of the information on seagrass distribution is generally very high compared to the environmental data available over large scale in marine domains (e.g. global bathymetry data). The high resolution application and the model transfer (from calibration areas to North African coast) was possible taking advantage of Ocean Color products: the probability of presence of the species in a given area was modelled using a

  18. Use of a vehicle-modelling tool for predicting CO 2 emissions in the framework of European regulations for light goods vehicles

    Science.gov (United States)

    Fontaras, Georgios; Kouridis, Hariton; Samaras, Zissis; Elst, Daniel; Gense, Raymond

    The reduction of CO 2 emissions and fuel consumption from road transportation constitutes an important pillar of the EU commitment for implementing the Kyoto Protocol. Efforts to monitor and limit CO 2 emissions from vehicles can effectively be supported by the use of vehicle modelling tools. This paper presents the application of such a tool for predicting CO 2 emissions of vehicles under different operating conditions and shows how the results from simulations can be used for supporting policy analysis and design aiming at further reductions of the CO 2 emissions. For this purpose, the case of light duty goods (N1 category) vehicle CO 2 emissions control measures adopted by the EU is analysed. In order to understand how certain design and operating aspects affect fuel consumption, a number of N1 vehicles were simulated with ADVISOR for various operating conditions and the numerical results were validated against chassis dynamometer tests. The model was then employed for analysing and evaluating the new EU legislative framework that addresses CO 2 emissions from this vehicle class. The results of this analysis have shown the weaknesses of the current regulations and revealed new potential in CO 2 emissions control. Finally the TREMOVE model was used for simulating a possible scenario for reducing CO 2 emissions at fleet level.

  19. Good decision making requires good communication.

    Science.gov (United States)

    Fischhoff, Baruch

    2012-11-01

    The methods used for regulatory decisions must facilitate three kinds of communication: (i) with individual experts who must translate their knowledge into usable form; (ii) among the experts whose pooled knowledge informs those choices; and (iii) between regulators and those affected by their choices. Decision-making methods vary in their reliance on expert judgement and computational methods and, hence, in their ability to meet the goals of sound decision making: breadth, depth, precision, neutrality, evaluability and transparency. An approach developed by the US FDA, the Benefit-Risk Framework, integrates judgement and computation, cognizant of their strengths and weaknesses. Its application both requires and facilitates good communication about risks and benefits.

  20. On good ETOL forms

    DEFF Research Database (Denmark)

    Skyum, Sven

    1978-01-01

    This paper continues the study of ETOL forms and good EOL forms done by Maurer, Salomaa and Wood. It is proven that binary very complete ETOL forms exist, good synchronized ETOL forms exist and that no propagating or synchronized ETOL form can be very complete.......This paper continues the study of ETOL forms and good EOL forms done by Maurer, Salomaa and Wood. It is proven that binary very complete ETOL forms exist, good synchronized ETOL forms exist and that no propagating or synchronized ETOL form can be very complete....

  1. Modern approaches regarding public goods

    OpenAIRE

    2015-01-01

    This article is trying to present general elements regarding public goods. It is presenting also all types of public goods and optimum provision of public goods. Public Goods designate goods, benefits which belong to all citizens, or community. Four categories of goods can be delimited Public goods; Private goods; Common goods; Taxable goods. We also introduce two new concepts of public goods: “Club Goods” and “Joint” Goods.

  2. International Grants and Cooperative Agreements

    Science.gov (United States)

    EPA provides grants and enters into cooperative agreements that support protecting human health and the environment while advancing U.S. national interests through international environmental collaboration.

  3. Labor Agreement Information System (LAIRS)

    Data.gov (United States)

    Office of Personnel Management — The Labor Agreement Information Retrieval System (LAIRS) is a database containing historical information on labor-management relations in the Federal Government. It...

  4. Applying dynamic simulation modeling methods in health care delivery research-the SIMULATE checklist: report of the ISPOR simulation modeling emerging good practices task force.

    Science.gov (United States)

    Marshall, Deborah A; Burgos-Liz, Lina; IJzerman, Maarten J; Osgood, Nathaniel D; Padula, William V; Higashi, Mitchell K; Wong, Peter K; Pasupathy, Kalyan S; Crown, William

    2015-01-01

    Health care delivery systems are inherently complex, consisting of multiple tiers of interdependent subsystems and processes that are adaptive to changes in the environment and behave in a nonlinear fashion. Traditional health technology assessment and modeling methods often neglect the wider health system impacts that can be critical for achieving desired health system goals and are often of limited usefulness when applied to complex health systems. Researchers and health care decision makers can either underestimate or fail to consider the interactions among the people, processes, technology, and facility designs. Health care delivery system interventions need to incorporate the dynamics and complexities of the health care system context in which the intervention is delivered. This report provides an overview of common dynamic simulation modeling methods and examples of health care system interventions in which such methods could be useful. Three dynamic simulation modeling methods are presented to evaluate system interventions for health care delivery: system dynamics, discrete event simulation, and agent-based modeling. In contrast to conventional evaluations, a dynamic systems approach incorporates the complexity of the system and anticipates the upstream and downstream consequences of changes in complex health care delivery systems. This report assists researchers and decision makers in deciding whether these simulation methods are appropriate to address specific health system problems through an eight-point checklist referred to as the SIMULATE (System, Interactions, Multilevel, Understanding, Loops, Agents, Time, Emergence) tool. It is a primer for researchers and decision makers working in health care delivery and implementation sciences who face complex challenges in delivering effective and efficient care that can be addressed with system interventions. On reviewing this report, the readers should be able to identify whether these simulation modeling

  5. Advice on Good Grooming.

    Science.gov (United States)

    Tingey, Carol

    1987-01-01

    Suggestions are presented from parents on how to help children with disabilities (with particular focus on Downs Syndrome) learn good grooming habits in such areas as good health, exercise, cleanliness, teeth and hair care, skin care, glasses and other devices, and social behavior. (CB)

  6. What Are Good Universities?

    Science.gov (United States)

    Connell, Raewyn

    2016-01-01

    This paper considers how we can arrive at a concept of the good university. It begins with ideas expressed by Australian Vice-Chancellors and in the "league tables" for universities, which essentially reproduce existing privilege. It then considers definitions of the good university via wish lists, classic texts, horror lists, structural…

  7. From Goods to Solutions

    DEFF Research Database (Denmark)

    Chakkol, Mehmet; Johnson, Mark; Raja, Jawwad

    2014-01-01

    Purpose – This paper aims to adopt service-dominant logic (SDL) to empirically explore network configurations resulting from the provision of goods, goods and services, and solutions. Design/methodology/approach – This paper uses a single, in-depth, exploratory case study in a truck manufacturer ...

  8. Good Mental Health

    Science.gov (United States)

    ... Trying to conceive, pregnancy, and mental health Menstruation, menopause, and mental health Women veterans and mental health When you need help Good mental ... in Spanish ( en español ) Good mental health Nutrition and mental health Exercise and mental health Sleep ...

  9. Making Good Tenure Decisions.

    Science.gov (United States)

    Becker, Samuel L.; Galvin, Kathleen M.; Houston, Marsha; Friedrich, Gustav W.; Pearson, Judy C.; Seiler, William J.; Trent, Judith S.

    2001-01-01

    Presents criteria and procedures that can help to substantially increase the probability of a good tenure decision. Notes that the tenure procedures must be designed and followed in a way that ensures, to the degree possible, validity, fairness, and equity. Stresses the importance of maintaining good records and mentoring. (SG)

  10. A Pretty Good Fit

    Science.gov (United States)

    Erickson, Tim

    2008-01-01

    We often look for a best-fit function to a set of data. This article describes how a "pretty good" fit might be better than a "best" fit when it comes to promoting conceptual understanding of functions. In a pretty good fit, students design the function themselves rather than choosing it from a menu; they use appropriate variable names; and they…

  11. THE ROLE OF REGIONAL TRADE AGREEMENTS IN THE GLOBAL ECONOMY

    Directory of Open Access Journals (Sweden)

    IRINA GABRIELA RADULESCU

    2010-12-01

    Full Text Available Regional and sub-regional groups having an integrative character appeared after the war and they aimed at harmonizing their economic policies, and, at the same time, they ensured, in accordance with the agreed degree of integration, free turnover of goods, products, services, capitals and labor force. By setting up these international economic organizations, the states of the world and especially developing countries wanted to improve their efforts for a sustained economic growth, to counteract the effects of the unequal external affairs and to eliminate underdevelopment. Some of the regional agreements that represent the new regionalism have been motivated politically and they were stimulated by the conviction that good agreements do not necessarily stand for good neighbors. Such agreements consolidate good diplomatic practices and their objective is to reduce the inevitable confrontation that may appear as a result of com

  12. Shear-tensile/implosion (STI) source model: a good substitute to moment tensor in single-well monitoring of hydrofrac-induced seismicity

    Science.gov (United States)

    Sileny, J.

    2011-12-01

    Moment tensor (MT) is a general dipole source, but for practice it may be too general, its generality causing troubles during its reconstruction from noisy data in the inverse process, which may be additionally ill-conditioned due to inexact hypocenter location and/or availability of a rough velocity/attenuation model only. Then, the retrieved source may be biased, containing artifacts of a low-quality data or the inconsistent inverse problem. The crucial point for success in the retrieval of the mechanism is the station configuration. The extreme case of depleted configuration is a one well monitoring providing a single-azimuth observation only, which is a frequent case during hydrofracturing treatment of oil and gas wells. Then, the complete moment tensor cannot be retrieved from far-field data and additional constraints are necessary. To avoid the trouble, it seems reasonable to assume a simpler source model directly describing the physical phenomena anticipated in the foci of the induced events. A simple combination of a shear slip with a tensile crack or 1D implosion - the STI model - is a good alternative to the moment tensor. Its advantage is twofold: (1) being described by smaller number of parameters, it removes the under-determination of the MT from single-azimuth observation, and (2) containing simple physical mechanisms only, namely a shear slip and tensile crack (or open crack implosion), it avoids unphysical sources like the compensated linear-vector dipole (CLVD) a priori. This feature helps a lot just in cases of a poor location or velocity modeling. We have tested the STI model in a series of synthetic experiments simulating a single well and two-well monitoring, the Cotton Valley (E Texas) hydrofracture treatment being the pattern of the observation. As theoretical mechanisms, a strike-slip and dip-slip with variable off-plane slip component were considered. The synthetic data were inverted by using Green's function simulating a mislocation of the

  13. Agreement dynamics on directed random graphs

    CERN Document Server

    Lipowski, Adam; Ferreira, Antonio L

    2016-01-01

    When agreement-dynamics models are placed on a directed random graph, a fraction of sites $\\exp(-z)$, where $z$ is the average degree, becomes permanently fixed or flickering. In the Voter model, which has no surface tension, such zealots or flickers freely spread their opinions and that makes the system disordered. For models with a surface tension, like the Ising model or the Naming Game model, their role is limited and such systems are ordered at large~$z$. However, when $z$ decreases, the density of zealots or flickers increases, and below a certain threshold ($z\\sim 1.9-2.0$) the system becomes disordered. Our results show that the agreement dynamics on directed networks is much different from their undirected analogues.

  14. Transportation of hazardous goods

    CERN Multimedia

    TS Department

    2008-01-01

    A general reminder: any transportation of hazardous goods by road is subject to the European ADR rules. The goods concerned are essentially the following: Explosive substances and objects; Gases (including aerosols and non-flammable gases such as helium and nitrogen); Flammable substances and liquids (inks, paints, resins, petroleum products, alcohols, acetone, thinners); Toxic substances (acids, thinners); Radioactive substances; Corrosive substances (paints, acids, caustic products, disinfectants, electrical batteries). Any requests for the transport of hazardous goods must be executed in compliance with the instructions given at this URL: http://ts-dep.web.cern.ch/ts-dep/groups/he/HH/adr.pdf Heavy Handling Section TS-HE-HH 73793 - 160364

  15. TRANSPORT OF COUNTERFEIT GOODS

    Directory of Open Access Journals (Sweden)

    Dagmar Babčanová

    2014-09-01

    Full Text Available The paper is focused on a current problem of transport of counterfeit goods in the European Union. Counterfeiting has a strong influence on the distribution organizations worldwide because most of counterfeit goods threaten the health and safety of consumers. Counterfeiting is a serious problem in the world economy today. The purpose of this paper is to point out the danger of counterfeiting in connection with the transport of Intellectual Property (IP rights - infringing goods. Background of the paper’s content is based on secondary data research of publicly available sources - international statistics and world reports.

  16. A good complaints system

    African Journals Online (AJOL)

    ... having a good complaints system in place can offer benefits that prevent an individual from ... While financial compensation is an understandable goal in ... of strategies to prevent similar errors occurring in the future. Patients should be given ...

  17. Good vs. Bad Cholesterol

    Science.gov (United States)

    ... Venous Thromboembolism Aortic Aneurysm More Good vs. Bad Cholesterol Updated:Apr 3,2017 Cholesterol can't dissolve ... test . View an animation of cholesterol . LDL (Bad) Cholesterol LDL cholesterol is considered the “bad” cholesterol because ...

  18. Inter-rater Agreement on Sentence Formality

    CERN Document Server

    Lahiri, Shibamouli

    2011-01-01

    Formality is one of the most important dimensions of writing style variation. In this study we conducted an inter-rater reliability experiment for assessing sentence formality on a five-point Likert scale, and obtained good agreement results as well as different rating distributions for different sentence categories. We also performed a difficulty analysis to identify the bottlenecks of our rating procedure. Our main objective is to design an automatic scoring mechanism for sentence-level formality, and this study is important for that purpose.

  19. Notes on Agreement in Itelmen

    Directory of Open Access Journals (Sweden)

    Jonathan David Bobaljik

    2002-01-01

    Full Text Available Agreement in Itelmen is represented by means of both prefixes and suffixes. While the prefixes reference subjects (of both transitive and intransitive verbs, the suffixal agreement morphemes on a given verb may reference the subject, the object, or an oblique argument, or some combination of these. We propose that the proper characterization of the factors that determine which arguments control suffixal agreement involves a division of labour between morphology and a notion of discourse prominence/salience. In essence, we propose that the suffixal agreement morpheme is an object agreement marker, but the features of the subject are reflected in this position when the object lacks the relevant features (for example, we treat third person as the lack of a person feature, or is absent altogether (thus, intransitive verbs agree twice with their subjects. When a verb occurs with an oblique as well as a direct object, discourse salience will determine which of these non-subject arguments will control object agreement. In addition to providing a description of a complex range of facts from Itelmen, the paper sheds light on the nature of “multiple exponence” and the role of “competition” among affixes for a particular position in the verbal agreement system.

  20. What if Things Get Worse? Really Grand Challenges for Modeling and Simulation in a Risky and Complex World or Modeling and Simulation for the "Greater Good"?

    Science.gov (United States)

    Fifrey, Priscilla

    2010-01-01

    Today Modeling and Simulation-- ---as an important practice or industry or area of expertise ----- is at a complex crossroad - a sort of cyber-highway--where these complexities meet-technical, economic, environmental, geopolitical and cultural. They may converge or collide. Let's not kid ourselves. It is all too much for anyone person or organization Malcolm Gladwell said it. "We have constructed a world in which the potential for high tech catastrophe is embedded in the fabric of everyday life." We are surrounded by problems that scream at us from our television, Internet and social networks along with billboards and protest signs. We face not just high tech catastrophes but, also, landslides, earthquakes, tornados, floods and hurricanes and large-scale criminality. Evil, war, famine and pestilence have not gone away. It is all too much to think about. My friend, George Peabody, who taught me everything I know about power said that addressing such issues requires that we constantly build our network, information resources and the credibility and visibility of our work. That is how we will build the power of simulation so it can change the world --even maybe, save it. We need all the help we can get and give one another because our human early warning systems appear to be out of kilter. We seem to have trouble imagining how small failings can continue to lead to catastrophic disaster. Think about O-rings and blowout preventers. One is reminded of the old nursery rhyme, "For want of a nail, a shoe was lost! for want of a shoe the horse was lost! for want of a rider the battle was lost and so the kingdom fell." Although the investigation will take more time for real answers, it is worrisome that a rig worker reported to the BBC that-- weeks before the explosion of Deep Ocean Horizon. -he identified a leak in the oil rig's safety equipment -the Control Pod of the blowout preventer which has giant shears designed to cut and seal off the well's main pipe. With both

  1. Material Transfer Agreement (MTA) | FNLCR

    Science.gov (United States)

    Material Transfer Agreements are appropriate for exchange of materials into or out of the Frederick National Labfor research or testing purposes, with no collaborative research by parties involving the materials.

  2. Corporate Integrity Agreement (CIA) documents

    Data.gov (United States)

    U.S. Department of Health & Human Services — OIG negotiates corporate integrity agreements (CIA) with health care providers and other entities as part of the settlement of Federal health care program...

  3. Corporate Integrity Agreement (CIA) documents

    Data.gov (United States)

    U.S. Department of Health & Human Services — OIG negotiates corporate integrity agreements (CIA) with health care providers and other entities as part of the settlement of Federal health care program...

  4. Cosmological bimetric model with interacting positive and negative masses and two different speeds of light, in agreement with the observed acceleration of the Universe

    Science.gov (United States)

    Petit, J. P.; D'Agostini, G.

    2014-10-01

    An extension of a previously published model of a bimetric Universe is presented, where the speeds of light associated to positive and negative mass species are different. As shown earlier, the asymmetry of the model explains the acceleration of the positive species, while the negative one slows down. Asymmetry affects scale factors linked to lengths, times and speeds of light; so that if a mass inversion of a craft can be achieved, then interstellar travels would become non-impossible at a velocity less than the speed of light of the negative sector, and possibly much higher than that of the positive sector.

  5. Mass Customizing IT Service Agreements

    OpenAIRE

    Brocke, Henrik Finn; Uebernickel, Falk; Brenner, Walter

    2010-01-01

    IT service providers shall achieve both cost reduction in their IT operations and customer individuality in service agreements. This article suggests adapting the well known principle of mass customization to balance individuality and standardization in service agreements. Dependent on the commitment modularity type, its employment may not only save time and resources at the point of customer involvement but also allow the pre-engineering of repeatable processes of provisioning and IT operati...

  6. Rater agreement in lung scintigraphy.

    Science.gov (United States)

    Christiansen, F; Andersson, T; Rydman, H; Qvarner, N; Måre, K

    1996-09-01

    The PIOPED criteria in their original and revised forms are today's standards in the interpretation of ventilation-perfusion scintigraphy. When the PIOPED criteria are used by experienced raters with training in consensus interpretation, the agreement rates have been demonstrated to be excellent. Our purpose was to investigate the rates of agreement between 2 experienced raters from different hospital who had no training in consensus interpretation. The 2 raters investigated a population of 195 patients. This group included 72 patients from a previous study who had an intermediate probability of pulmonary embolism and who had also been examined by pulmonary angiography. The results demonstrated moderate agreement rates with a kappa value of 0.54 (0.45-0.63 in a 95% confidence interval), which is similar to the kappa value of the PIOPED study but significantly lower than the kappa values of agreement rates among consensus-trained raters. There was a low consistency in the intermediate probability category, with a proportional agreement rate of 0.39 between the experienced raters. The moderate agreement rates between raters from different hospitals make it difficult to compare study populations of a certain scintigraphic category in different hospitals. Further investigations are mandatory for accurate diagnosis when the scintigrams are in the category of intermediate probability of pulmonary embolism.

  7. Rater agreement in lung scintigraphy

    Energy Technology Data Exchange (ETDEWEB)

    Christiansen, F. [Oerebro Medical Center Hospital (Sweden). Dept. of Diagnostic Radiology; Andersson, T. [Oerebro Medical Center Hospital (Sweden). Dept. of Diagnostic Radiology; Rydman, H. [Oerebro Medical Center Hospital (Sweden). Dept. of Diagnostic Radiology; Qvarner, N. [Oerebro Medical Center Hospital (Sweden). Dept. of Diagnostic Radiology; Maare, K. [Huddinge Univ. Hospital (Sweden). Dept. of Diagnostic Radiolgy

    1996-09-01

    Purpose: The PIOPED criteria in their original and revised forms are today`s standards in the interpretation of ventilation-perfusion scintigraphy. When the PIOPED criteria are used by experienced raters with training in consensus interpretation, the agreement rates have been demonstrated to be excellent. Our purpose was to investigate the rates of agreement between 2 experienced raters from different hospitals who had no training in consensus interpretation. Material and Methods: The 2 raters investigated a population of 195 patients. This group included 72 patients from a previous study who had an intermediate probability of pulmonary embolism and who had also been examined by pulmonary angiography. Results: The results demonstrated moderate agreement rates with a kappa value of 0.54 (0.45-0.63 in a 95% confidence interval), which is similar to the kappa value of the PIOPED study but significantly lower than the kappa values of agreement rates among consensus-trained raters. There was a low consistency in the intermediate probability category, with a proportional agreement rate of 0.39 between the experienced raters. Conclusion: The moderate agreement rates between raters from different hospitals make it difficult to compare study populations of a certain scintigraphic category in different hospitals. Further investigations are mandatory for accurate diagnosis when the scintigrams are in the category of intermediate probability of pulmonary embolism. (orig.).

  8. Abusing Good Intentions

    Directory of Open Access Journals (Sweden)

    Tamas Bereczkei

    2015-06-01

    Full Text Available The present study aims to understand how Machiavellians switch from one kind of response to another in different circumstances to maximize their profit. We set up a specific experimental paradigm that involved both a cooperative and competitive version of a public goods game. We found that Machiavellianism accounts for the total amount of money paid by the players (N = 144 across five rounds in the cooperative but not in the competitive game. Compared with the others, individuals with higher scores on Mach scale contributed less to the public goods in the cooperative condition, but no difference was found in the competitive condition. Finally, this relationship was influenced by the sequence of the games. These results indicate that Machiavellians skillfully evaluate social environments and strive to exploit those with abundant contributions to public goods.

  9. Industrial Psychology: Goodness of fit? Fit for goodness?

    Directory of Open Access Journals (Sweden)

    Leon J. van Vuuren

    2010-12-01

    Full Text Available Orientation: This theoretical opinion-based paper represents a critical reflection on the relevance of industrial psychology.Research purpose: Against a historical-developmental background of the discipline, the inquiry questions its goodness of fit, that is its contribution to organisation and society.Motivation for the study: Regular introspection in the discipline ensures that it remains relevant in both science and practice. As such, such introspection calls for a meta-theoretical imperative, to ensure that industrial psychology is fully aware of how the theoretical models applied in the discipline influence people and the society that they form part of.Research design, approach and method: The question of industrial psychology’s potential fit for goodness that is broader than what is merely good for the organisation and its employees is explored with a view to enhancing its relevance. The exploration is conducted through the utilisation of theoretical argumentation in which industrial psychology is analysed in terms of contextual considerations that require the discipline to evaluate its real versus its potential contribution to society.Main findings: It is found that the fit is limited to its relevance for inwardly focused organisational behaviour due to its endorsement of the instrumental (strategic motives of organisations that subscribe to an owner and/or shareholder agenda.Practical/managerial implications: In light of the main finding, industrial psychology’s potential fit for goodness is explored with a view to enhancing its relevance in an era of goodness. The creation of a scientific and practical interface between industrial psychology and business ethics is suggested to facilitate movement away from a descriptive approach.Contribution/value-add: The heuristics of reflection, reform, research and resources are suggested to facilitate movement towards a normative (multiple stakeholder paradigm aimed at broad based goodness and

  10. Further steps in the modeling of behavioural crowd dynamics, good news for safe handling. Comment on "Human behaviours in evacuation crowd dynamics: From modelling to "big data" toward crisis management" by Nicola Bellomo et al.

    Science.gov (United States)

    Knopoff, Damián A.

    2016-09-01

    The recent review paper [4] constitutes a valuable contribution on the understanding, modeling and simulation of crowd dynamics in extreme situations. It provides a very comprehensive revision about the complexity features of the system under consideration, scaling and the consequent justification of the used methods. In particular, macro and microscopic models have so far been used to model crowd dynamics [9] and authors appropriately explain that working at the mesoscale is a good choice to deal with the heterogeneous behaviour of walkers as well as with the difficulty of their deterministic identification. In this way, methods based on the kinetic theory and statistical dynamics are employed, more precisely the so-called kinetic theory for active particles [7]. This approach has successfully been applied in the modeling of several complex dynamics, with recent applications to learning [2,8] that constitutes the key to understand communication and is of great importance in social dynamics and behavioral sciences.

  11. Public goods and procreation.

    Science.gov (United States)

    Anomaly, Jonathan

    2014-01-01

    Procreation is the ultimate public goods problem. Each new child affects the welfare of many other people, and some (but not all) children produce uncompensated value that future people will enjoy. This essay addresses challenges that arise if we think of procreation and parenting as public goods. These include whether individual choices are likely to lead to a socially desirable outcome, and whether changes in laws, social norms, or access to genetic engineering and embryo selection might improve the aggregate outcome of our reproductive choices.

  12. Partition Model-Based 99mTc-MAA SPECT/CT Predictive Dosimetry Compared with 90Y TOF PET/CT Posttreatment Dosimetry in Radioembolization of Hepatocellular Carcinoma: A Quantitative Agreement Comparison.

    Science.gov (United States)

    Gnesin, Silvano; Canetti, Laurent; Adib, Salim; Cherbuin, Nicolas; Silva Monteiro, Marina; Bize, Pierre; Denys, Alban; Prior, John O; Baechler, Sebastien; Boubaker, Ariane

    2016-11-01

    (90)Y-microsphere selective internal radiation therapy (SIRT) is a valuable treatment in unresectable hepatocellular carcinoma (HCC). Partition-model predictive dosimetry relies on differential tumor-to-nontumor perfusion evaluated on pretreatment (99m)Tc-macroaggregated albumin (MAA) SPECT/CT. The aim of this study was to evaluate agreement between the predictive dosimetry of (99m)Tc-MAA SPECT/CT and posttreatment dosimetry based on (90)Y time-of-flight (TOF) PET/CT. We compared the (99m)Tc-MAA SPECT/CT results for 27 treatment sessions (25 HCC patients, 41 tumors) with (90)Y SIRT (7 glass spheres, 20 resin spheres) and the posttreatment (90)Y TOF PET/CT results. Three-dimensional voxelized dose maps were computed from the (99m)Tc-MAA SPECT/CT and (90)Y TOF PET/CT data. Mean absorbed dose ([Formula: see text]) was evaluated to compute the predicted-to-actual dose ratio ([Formula: see text]) in tumor volumes (TVs) and nontumor volumes (NTVs) for glass and resin spheres. The Lin concordance ([Formula: see text]) was used to measure accuracy ([Formula: see text]) and precision (ρ). Administered activity ranged from 0.8 to 1.9 GBq for glass spheres and from 0.6 to 3.4 GBq for resin spheres, and the respective TVs ranged from 2 to 125 mL and from 6 to 1,828 mL. The mean dose [Formula: see text] was 240 Gy for glass and 122 Gy for resin in TVs and 72 Gy for glass and 47 Gy for resin in NTVs. [Formula: see text] was 1.46 ± 0.58 (0.65-2.53) for glass and 1.16 ± 0.41 (0.54-2.54) for resin, and the respective values for [Formula: see text] were 0.88 ± 0.15 (0.56-1.00) and 0.86 ± 0.2 (0.58-1.35). DR variability was substantially lower in NTVs than in TVs. The Lin concordance between [Formula: see text] and [Formula: see text] (resin) was significantly better for tumors larger than 150 mL than for tumors 150 mL or smaller ([Formula: see text] = 0.93 and [Formula: see text] = 0.95 vs. [Formula: see text] = 0.57 and [Formula: see text] = 0.93; P < 0.05). In (90)Y

  13. Research on selecting the sale channel model of the information goods%信息产品销售渠道模式选择研究

    Institute of Scientific and Technical Information of China (English)

    刘志勇; 李敏强; 寇纪淞

    2013-01-01

    The information goods manufacturer can distribute their products through many kinds of channels, e.g. online direct sale and traditional retail marketing. The retailer pays a manufacturer based on two common payment schemes, the Fixed-fee policy and the Per-copy policy. Which channel and sell model is preferable for the manufacture? The product quality, the price, and the customer acceptance for direct channel are the decisive factors. Through analyzing the decision behaviors of the manufacture, retailer and consumer, the model of maximizing the manufacture's profit is presented in the presence of both direct and retail channel. Based on the comparison among different channels, the paper shows that when the valuation for the information goods has a uniform distribution, the manufacture prefers the Fixed-fee policy through the direct sale channel, whereas the Per-copy policy is preferable through dual-channel. The best sale channel strategy is to distribute the high-quality version through the direct sale channel and the low-quality version through the retailing channel for the manufacturer.%信息产品供应商在销售产品时有多种渠道可以选择,可以通过在线直销,也可以通过传统的零售渠道方式.而在零售模式下,供应商可以与零售商之间采用Fixed-fee协议或Per-copy协议.供应商在面临这些不同的销售渠道和销售方式时,产品质量、销售价格以及消费者对直销渠道的接受程度等因素决定了最终的选择方式.通过对供应商、零售商和消费者的决策行为进行分析,给出了供应商通过直销渠道和零售渠道销售产品下的收益最优化模型,并对结果进行了比较.研究表明当消费者对产品评价值服从均匀分布的情况时,零售渠道下采用Fixed-fee模式有利于供应商,而在双重渠道下,供应商采用Per-copy模式更有利.而且当供应商采用直销渠道销售高质量产品,由零售渠道销售较低质量产品时,供应商能获得最大收益.

  14. LHC Report: machine commissioning - looking good

    CERN Multimedia

    CERN Bulletin

    2016-01-01

    Since first beam was injected on Friday, 25 March, the recommissioning of the LHC has made good progress.   An event display showing the first collisions after the 2015 year-end technical stop as seen by the CMS experiment. At present, work is being performed with either probe bunches (around 1010 protons per bunch) or single nominal bunches (1.1 x 1011 protons per bunch). This procedure is intended to ensure safe operation before full qualification of the machine protection set-up. Beam has been taken up the ramp to 6.5 TeV and through the squeeze to the planned 2016 operating scenario. The optics (i.e. the global focusing properties of the whole ring) have been measured and corrected to an unprecedented level: there is now excellent agreement between the machine model and the actual LHC. Some preliminary measurements of the global aperture have been performed and there are no apparent bottlenecks. The position of the ULO (Unidentified Lying Object) had been probed and it is in a similar positio...

  15. Good And Bad News

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    <正>A distinguished scientist was participating in a panel discussion on the results of the nation’s future water supply.“Gentlemen,” he said.“I have some good news and bad news for you,Our study shows that by the year 2010 everyone will be drinking recycled sewage from

  16. Public Education, Public Good.

    Science.gov (United States)

    Tomlinson, John

    1986-01-01

    Criticizes policies which would damage or destroy a public education system. Examines the relationship between government-provided education and democracy. Concludes that privatization of public education would emphasize self-interest and selfishness, further jeopardizing the altruism and civic mindedness necessary for the public good. (JDH)

  17. GOOD GOVERNANCE AND TRANSFORMATION

    Directory of Open Access Journals (Sweden)

    Hans-Jürgen WAGENER

    2005-12-01

    Full Text Available Transformation of a totalitarian, basically administratively coordinated system into a democratic one that is coordinated predominantly by markets and competition has been triggered by, among others, the perception of a serious deficit in welfare and happiness. Public policy has a special task transforming the economic order by liberalisation, privatisation, stabilisation and the installation of institutions that are supportive for competition. After 15 years since transformation began, there are sufficiently differentiated success stories to test the hypothesis: it was good governance that is responsible for success and bad governance for failure. The empirical results support the “Lorenzetti hypothesis”: where freedom, security and trust prevail, the economy flourishes, where they are lacking, the costs of long-term investment are too high. The initial conditions of transition countries seem to be quite similar, nevertheless, even there one can discern good and bad governance. The extent of socialist lawfulness, planning security, cronyism and corruption differed widely between East Berlin and Tashkent. And a good deal of such variations can be found in the pre-socialist history of these countries. However, the main conclusion is that the co-evolution hypothesis states that both, welfare and good governance, go together.

  18. For the Common Good

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    A consensus has been reached, and if s time to translate it into concrete action. That is what the G20 leaders are expected to do after their London meeting earlier this month. The G20 London summit’s generous rescue plan is good news for the world economy, finally dismissing earlier doubts about whether the

  19. My Good Friend

    Institute of Scientific and Technical Information of China (English)

    王雨航

    2008-01-01

    @@ I have a good friend. My mother even says that he is a member of our family. His name is Peter. He has two bright eyes, a small nose, a big mouth and a long tail. He is very lovely and looks like a white flowers. He likes drinking milk and eating meat.

  20. Reconsidering the "Good Divorce"

    Science.gov (United States)

    Amato, Paul R.; Kane, Jennifer B.; James, Spencer

    2011-01-01

    This study attempted to assess the notion that a "good divorce" protects children from the potential negative consequences of marital dissolution. A cluster analysis of data on postdivorce parenting from 944 families resulted in three groups: cooperative coparenting, parallel parenting, and single parenting. Children in the cooperative coparenting…

  1. Types of contracts and agreements guide. Part 1

    Energy Technology Data Exchange (ETDEWEB)

    1981-05-01

    The purpose of this volume is to be helpful in providing a comprehensive introduction to a wide variety of contract types and agreements, including a consideration of small purchase procedures and multiyear procurement. In both format and content, it is designed to help those persons who influence the determination of the types of contracts and agreements to be employed in acquiring goods and services for the Department of Energy. Information is presented on selecting and negotiating types of contract compensation arrangements; fixed-price type contract compensation arrangements, including small purchases and multiyear procurement; cost-reimbursement type contract compensation arrangements; other types of contract compensation agreements; and basic agreements and basic ordering agreements. (LCL)

  2. The high mass end of the stellar mass function: Dependence on stellar population models and agreement between fits to the light profile

    Science.gov (United States)

    Bernardi, M.; Meert, A.; Sheth, R. K.; Fischer, J.-L.; Huertas-Company, M.; Maraston, C.; Shankar, F.; Vikram, V.

    2017-01-01

    We quantify the systematic effects on the stellar mass function which arise from assumptions about the stellar population, as well as how one fits the light profiles of the most luminous galaxies at z ˜ 0.1. When comparing results from the literature, we are careful to separate out these effects. Our analysis shows that while systematics in the estimated comoving number density which arise from different treatments of the stellar population remain of order ≤0.5 dex, systematics in photometry are now about 0.1 dex, in contrast to some recent claims in the literature. Compared to these more recent analyses, previous work based on Sloan Digital Sky Survey (SDSS) pipeline photometry leads to underestimates of ρ★( ≥ M★) by factors of 3 - 10 in the mass range 1011 - 1011.6M⊙, but up to a factor of 100 at higher stellar masses. This impacts studies which match massive galaxies to dark matter halos. Although systematics which arise from different treatments of the stellar population remain of order ≤0.5 dex, our finding that systematics in photometry now amount to only about 0.1 dex in the stellar mass density is a significant improvement with respect to a decade ago. Our results highlight the importance of using the same stellar population and photometric models whenever low and high redshift samples are compared.

  3. Meet the good child

    DEFF Research Database (Denmark)

    Gram, Malene; Grønhøj, Alice

    2016-01-01

    to be appropriate child and parental behavior. The study takes a practice theoretical perspective, building on previous research on family consumption, and draws empirically on 35 interviews with 5–6 year-olds and 13 family interviews. Findings show that the children recognize the position of ‘the good child......’ and most often prefer to take on this position, which is confirmed by their parents. The children can describe how ‘the good child’—in their eyes—should behave. They prefer consensus and not being embarrassing or embarrassed. The study concludes that the children are strongly immersed in social norms...... and family practices, and that the Danish national/cultural context probably reinforces these children as independent consumers, who are well aware of the requirements of the consumer role. Childing practices are a standard with know-how and rules that these children argue they live by—at least most...

  4. A good patient?

    DEFF Research Database (Denmark)

    Campbell, Catherine; Scott, Kerry; Skovdal, Morten;

    2015-01-01

    Background: While patient-provider interactions are commonly understood as mutually constructed relationships,the role of patient behaviour, participation in interactions, and characteristics, particularly ideals surrounding notionsof ‘good’ and ‘bad’ patients, are under-examined. This article...... examines social representations of ‘a good patient’and how these representations affect patient-healthcare provider relationships and antiretroviral treatment (ART) forpeople living with HIV. Methods: Using thematic network analysis, we examined interview and focus group transcripts involving 25healthcare...... staff, 48 ART users, and 31 carers of HIV positive children, as well as field notes from over 100 h ofethnographic observation at health centres in rural Zimbabwe. Results: Characteristics of a good patient include obedience, patience, politeness, listening, enthusiasm fortreatment, intelligence...

  5. Sustainability = Good Design

    Directory of Open Access Journals (Sweden)

    Kevin Stelzer

    2006-12-01

    Full Text Available Sustainable design is fundamentally a subset of good design. The description of good design will eventually include criteria for the creation of a healthy environmentand energy efficiency. These goals will be achieved by an emergent paradigm of design practice: integration. At every level design interests will come together to facilitate common goals for the creation of a rewarding present and a healthy future. Interdisciplinary design teams will flourish. Inter-accommodating and fluidly communicating political structures will grow. Coalescing social values and economic forces will propel integrated strategies. Unique and innovative solutions will increasingly become the objective. One eventual outcome of this integrated or sustainable design practice will be the development of buildings that produce more energy than they consume.

  6. Framework agreements in public procurement

    DEFF Research Database (Denmark)

    Andrecka, Marta; Telles, Pedro

    2015-01-01

    Interview with Dr. Marta Andrecka, Postdoctoral Fellow at the Department of Law at the University of Aarhus, where she is currently working on a project called "Dealing with legal loopholes and uncertainties within EU public procurement law regarding framework agreements" sponsored by the Carlsberg...... Foundation. Before taking up her present position she carried out her doctoral research in Denmark and Australia and worked at law offices in both Poland and the UK. The topic for today’s talk is framework agreements, a relatively popular way of undertaking public procurement...

  7. A Good Plan

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    Now I am a middle school student,and I have some experience on study.I think a good plan is the most important. In the middle school,there are a lot of things to do every day.So you must have a plan to help you do all the things,or you will be very busy and can't do things well.

  8. 76 FR 4369 - Interim Deputation Agreements; Interim BIA Adult Detention Facility Guidelines

    Science.gov (United States)

    2011-01-25

    ... Bureau of Indian Affairs Interim Deputation Agreements; Interim BIA Adult Detention Facility Guidelines... publication of the Interim BIA Adult Detention Facility Guidelines and the Interim Model Deputation Agreements... of 2010. Three Interim Model Deputation Agreements will be used: one agreement for tribes in...

  9. Inter-observer agreement of CT measurement of the glenoid bone surface by the CT Pico method: Comparison with laser in a cadaveric model

    Energy Technology Data Exchange (ETDEWEB)

    De Filippo, Massimo; Saba, Luca; Negrini, Giulio; Silva, Mario [University of Parma, Department of Radiology, Parma (Italy); Pedrazzi, Giuseppe [Universita di Parma, Department of Neuroscience. Unita di Biofisica e Fisica Medica - Plesso Biotecnologico Integrato, Parma (Italy); Pogliacomi, Francesco [University of Parma, Department of Orthopedic Surgery, Parma (Italy); Castagna, Alessandro [Istituto Clinico Humanitas, Section of Orthopedic Surgery, Rozzano, MI (Italy)

    2015-10-15

    The aim of this study was to test reproducibility of the CT Pico method in a cadaveric model and to compare CT Pico measurements with a high-precision laser probe for optical scanning. The glenoid surface of ten dried cadaveric scapulae (with intact surface) was measured by and high-precision laser probe for optical scanning, the latter being assumed as a reference standard. Measurements were done according to the Pico technique, using a circle-shaped region of interest (ROI) that was placed on the inferior glenoid rim. Measurements obtained using the CT Pico method (three readers) and with laser were compared to assess differences between radiological assessment and the reference standard. Each observer performed two repeated measurements from each scapulae (20 for each observer). Mean differences between laser measurements and each CT reader were 18.4 % (range, -4 to 61 %) for reader 1, 12.4 % (range, -15 to 64 %) for reader 2, and 11 % (range, -14 to 58 %) for reader 3. Considering all the 60 measurements made by the three readers, 39 measurements out of 60 (65 %) were outside the range [-5 %; +5 %] while 26 measurements (43 %) are outside the range [-10 %; +10 %]. The largest differences (positive and negative) were +64 and -14 %, respectively. Intra-operator reproducibility was high in most cases intraclass correlation coefficient (ICC) =0.93, ICC = 0.91, ICC = 0.93 and Lin's Concordance correlation coefficient (CCC) = 0.92, CCC = 0.90, CCC = 0.92 for reader 1 to 3, respectively. However, in five cases the CT Pico measurements showed absolute differences between the first and second measurements that exceeded 10 %. The inter-observer variability for CT measurement of the glenoid surface using the CT Pico method was high when compared with laser, in the assessment of glenoid surface in cadaveric specimens, thus the CT Pico method is not reliable and could cause errors in the clinical management of the patient. Level of evidence. Level II, Development of

  10. Can bilateral trade agreements help induce free trade?

    OpenAIRE

    Riezman, Raymond Glenn

    1999-01-01

    There has been growing debate about whether bilateral trade agreements are damaging multilateral efforts to eliminate barriers to international trade. This paper develops a model in which trading blocks always charge optimal tariffs and make trade agreements based on strategic considerations. We ask a very simple question. Does the fact that trading blocks can form bilateral trade agreements make Free trade less likely to occur? The answer is that it depends on the size distribution of the tr...

  11. Block Transfer Agreement Evaluation Project

    Science.gov (United States)

    Bastedo, Helena

    2010-01-01

    The objective of this project is to evaluate for the British Columbia Council on Admissions and Transfer (BCCAT) the effectiveness of block transfer agreements (BTAs) in the BC Transfer System and recommend steps to be taken to improve their effectiveness. Findings of this study revealed that institutions want to expand block credit transfer;…

  12. Modeling of the clinical and economic impact of a risk-sharing agreement supporting a treat-to-target strategy in the management of patients with rheumatoid arthritis in France.

    Science.gov (United States)

    Fagnani, Francis; Pham, Thao; Claudepierre, Pascal; Berenbaum, Francis; De Chalus, Thibault; Saadoun, Carine; Joubert, Jean-Michel; Fautrel, Bruno

    2016-08-01

    To evaluate the cost-effectiveness of a Treat-to-Target strategy with certolizumab pegol in patients with rheumatoid arthritis in the context of a pay-for-performance agreement in which medication costs are refunded in case of discontinuation during the first 3 months of treatment. The Treat-to-Target strategy consisted of a systematic switch to second-line tumor necrosis factor (TNF)α inhibitor in case of an unmet ACR50 response at 3 months compared to current routine clinical practice. A reference cohort treated first-line with certolizumab pegol according to current practice without systematic switching was considered as the comparator. A decision-tree model was constructed to estimate clinical outcome (health assessment questionnaire-disability index or HAQ-DI score), time spent in ACR50 response (ACR 50), and direct costs of treatment over a 2-year period. HAQ scores were derived from American College of Rheumatology 50 (ACR50) responses. All TNFα inhibitors were assumed to have equivalent efficacy and tolerability. Costs were estimated at 2013 French retail prices (date of the pay-for-performance agreement). The mean duration of an ACR50 response was 1.23 years in the Treat-to-Target strategy certolizumab pegol cohort vs 0.98 years in the reference cohort, resulting in a mean gain in HAQ at 24 months of 0.117. The Treat-to-Target strategy with a mix of TNFα inhibitors as second-line therapy was more expensive than the reference strategy in absolute terms, but this difference was entirely offset by the pay-for-performance agreement. The Treat-to-Target strategy was, thus, cost-neutral over a 2-year period after the payback of CZP cost for patients not achieving the target at 3 months. In the context of a pay-for-performance agreement, the management of patients with rheumatoid arthritis using a Treat-to-Target strategy with certolizumab pegol in first line is dominant compared to standard use of this drug in the French setting in 2013.

  13. Evaluating the agreement between measurements and models of net ecosystem exchange at different times and time scales using wavelet coherence: an example using data from the North American Carbon Program Site-Level Interim Synthesis

    Directory of Open Access Journals (Sweden)

    P. C. Stoy

    2013-02-01

    Full Text Available Earth system processes exhibit complex patterns across time, as do the models that seek to replicate these processes. Model output may or may not be significantly related to observations at different times and on different frequencies. Conventional model diagnostics provide an aggregate view of model-data agreement, but usually do not identify the time and frequency patterns of model misfit, leaving unclear the steps required to improve model response to environmental drivers that vary on characteristic frequencies. Wavelet coherence can quantify the times and frequencies at which models and measurements are significantly different. We applied wavelet coherence to interpret the predictions of twenty ecosystem models from the North American Carbon Program (NACP Site-Level Interim Synthesis when confronted with eddy covariance-measured net ecosystem exchange (NEE from ten ecosystems with multiple years of available data. Models were grouped into classes with similar approaches for incorporating phenology, the calculation of NEE, and the inclusion of foliar nitrogen (N. Models with prescribed, rather than prognostic, phenology often fit NEE observations better on annual to interannual time scales in grassland, wetland and agricultural ecosystems. Models that calculate NEE as net primary productivity (NPP minus heterotrophic respiration (HR rather than gross ecosystem productivity (GPP minus ecosystem respiration (ER fit better on annual time scales in grassland and wetland ecosystems, but models that calculate NEE as GPP – ER were superior on monthly to seasonal time scales in two coniferous forests. Models that incorporated foliar nitrogen (N data were successful at capturing NEE variability on interannual (multiple year time scales at Howland Forest, Maine. Combined with previous findings, our results suggest that the mechanisms driving daily and annual NEE variability tend to be correctly simulated, but the magnitude of these fluxes is often

  14. PHP The Good Parts

    CERN Document Server

    MacIntyre, Peter

    2010-01-01

    Get past all the hype about PHP and dig into the real power of this language. This book explores the most useful features of PHP and how they can speed up the web development process, and explains why the most commonly used PHP elements are often misused or misapplied. You'll learn which parts add strength to object-oriented programming, and how to use certain features to integrate your application with databases. Written by a longtime member of the PHP community, PHP: The Good Parts is ideal for new PHP programmers, as well as web developers switching from other languages. Become familiar w

  15. Good supervision and PBL

    DEFF Research Database (Denmark)

    Otrel-Cass, Kathrin

    This field study was conducted at the Faculty of Social Sciences at Aalborg University with the intention to investigate how students reflect on their experiences with supervision in a PBL environment. The overall aim of this study was to inform about the continued work in strengthening supervision...... at this faculty. This particular study invited Master level students to discuss: • How a typical supervision process proceeds • How they experienced and what they expected of PBL in the supervision process • What makes a good supervision process...

  16. Promoting good practice.

    Science.gov (United States)

    2004-04-01

    Meanwhile, the Scottish Executive's Centre for Change and Innovation, which was set up to identify and promote good practice and increase the pace of change to benefit patients, has an informative website at www.cci.scot.nhs.uk which provides details of a range of innovative projects currently underway. The site has main sections focusing on, among other things, national and local programmes, best practice examples, feedback, advice on managing teams, and developing organisations. It also provides a link to the NHS Education for Scotland electronic library.

  17. Good Governance in the EU

    Directory of Open Access Journals (Sweden)

    Gina Livioara GOGA

    2009-10-01

    Full Text Available Considering the EU adhesion, good governance has been analyzed from different perspectives, in the judicial literature being an analytic model or a normative concept. Some authors have wondered if this concept is a fashion, comprising some older ideas and principles, while other authors have asserted that the reasons why different methods of governance appear in the EU are based on “the complexity and the uncertainty of the problems on the agenda, an irreducible, the new approaches on public administration and law, hidden competencies, legitimacy and subsidiarity”. At a normative level, the White Paper of European Governance consecrated five principles on which good governance is based upon: openness, participation, responsibility, efficiency and coherence.

  18. Knowledge asymmetries about product "goodness"

    DEFF Research Database (Denmark)

    Kampf, Constance

    become recognized standards in mainstream markets-i.e. organic, fair trade.   From a business perspective, Corporate Social Responsibility (CSR) is considered in terms of consumer behavior in response to corporate communication.  For example, Mohr & Webb (2005), in their study in consumer behavior...... criterion" used by companies in sense-giving communication aimed at consumers to understanding knowledge asymmetries involved in an ongoing process of constructing CSR knowledge about products, or product "goodness" among consumers, NGOs, B-corporations, and corporations through an Iphone application...... of institutionalization of CSR as a company-focused model (Schultz & Wehmeier 2010) to a focus on inter-institutional and institution-consumer knowledge asymmetries affecting consumer sensemaking practices in purchasing.  Data from the Good GuideTM Ipod application, YouTube Videos about a legal controversy involving...

  19. Prestige from the Provision of Collective Goods

    Science.gov (United States)

    Whitmeyer, Joseph M.

    2007-01-01

    Groups often confer high prestige on individuals even when few members of the group ever interact with those individuals. To account for this phenomenon, I present a multilevel simulation model of a group's selection of its top-ranked member. In the model, the mechanism for social agreement on a top person is aggregation of group members' private…

  20. Evaluating the agreement between tumour volumetry and the estimated volumes of tumour lesions using an algorithm

    Energy Technology Data Exchange (ETDEWEB)

    Laubender, Ruediger P. [German Cancer Consortium (DKTK), Heidelberg (Germany); University Hospital Munich - Campus Grosshadern, Institute of Medical Informatics, Biometry, and Epidemiology (IBE), Munich (Germany); German Cancer Research Center (DKFZ), Heidelberg (Germany); Lynghjem, Julia; D' Anastasi, Melvin; Graser, Anno [University Hospital Munich - Campus Grosshadern, Institute for Clinical Radiology, Munich (Germany); Heinemann, Volker; Modest, Dominik P. [University Hospital Munich - Campus Grosshadern, Department of Medical Oncology, Munich (Germany); Mansmann, Ulrich R. [University Hospital Munich - Campus Grosshadern, Institute of Medical Informatics, Biometry, and Epidemiology (IBE), Munich (Germany); Sartorius, Ute; Schlichting, Michael [Merck KGaA, Darmstadt (Germany)

    2014-07-15

    To evaluate the agreement between tumour volume derived from semiautomated volumetry (SaV) and tumor volume defined by spherical volume using longest lesion diameter (LD) according to Response Evaluation Criteria In Solid Tumors (RECIST) or ellipsoid volume using LD and longest orthogonal diameter (LOD) according to World Health Organization (WHO) criteria. Twenty patients with metastatic colorectal cancer from the CIOX trial were included. A total of 151 target lesions were defined by baseline computed tomography and followed until disease progression. All assessments were performed by a single reader. A variance component model was used to compare the three volume versions. There was a significant difference between the SaV and RECIST-based tumour volumes. The same model showed no significant difference between the SaV and WHO-based volumes. Scatter plots showed that the RECIST-based volumes overestimate lesion volume. The agreement between the SaV and WHO-based relative changes in tumour volume, evaluated by intraclass correlation, showed nearly perfect agreement. Estimating the volume of metastatic lesions using both the LD and LOD (WHO) is more accurate than those based on LD only (RECIST), which overestimates lesion volume. The good agreement between the SaV and WHO-based relative changes in tumour volume enables a reasonable approximation of three-dimensional tumour burden. (orig.)

  1. Strangeness suppression in the unquenched quark model

    CERN Document Server

    Bijker, Roelof; Santopinto, Elena

    2016-01-01

    In this contribution, we discuss the strangeness suppression in the proton in the framework of the unquenched quark model. The theoretical results are in good agreement with the values extracted from CERN and JLab experiments.

  2. GOOD OLD OIL

    Directory of Open Access Journals (Sweden)

    Akula Annapurna

    2013-10-01

    Full Text Available Nowadays everybody is getting puzzled and confused about choosing right oil for daily use. Most of the ads in the market revolving around sunflower oil only with different brand names claiming it is heart friendly. In recent years, younger generation may not be familiar much with our age old traditional oils like sesame oil. Sesame oil is also called as gingelly oil or til oil is rich in vitamin E and B. It is a good source of minerals like calcium, manganese and phosphorous and promotes healing. It contains high amounts of polyunsaturated fatty acids and decreases high blood pressure. Because of its antioxidant property, it decreases cholesterol and good for heart. It acts like a sedative, relieves mental fatigue and promotes sleep when it is used for head massage. It is having laxative nature, relieving constipation. When applied topically on to the skin it is acting as an excellent moisturizer and an emollient. Because of its natural antibacterial, antiviral and anti-inflammatory properties it keeps away the skin and tooth infections. Hence, it can be used by one and all without any hesitation for regular cooking. However, it is not preferred for deep frying. Let us once again say OLD IS GOLD

  3. The Good Investment.

    Science.gov (United States)

    Prescott, John E; Fresne, Julie A; Youngclaus, James A

    2017-07-01

    The authors reflect on the article in this issue entitled "Borrow or Serve? An Economic Analysis of Options for Financing a Medical School Education" by Marcu and colleagues, which makes a compelling case that a medical school education is a good investment, no matter what financing option students use, from federal service programs to federal loans. The lead author of this Commentary shares lessons learned from his own medical school education, which was funded by an Armed Forces Health Professions Scholarship, and from his current position interacting with medical students across the United States.Regardless of the financing path they choose, all students should understand basic financial concepts and the details of the various pathways that are available to pay for their medical school education, as well as how each could potentially impact their own future and that of their families. One underappreciated aspect of financing a medical school education is that federal repayment scenarios can link loan payments to income, rather than debt levels, which means that all physicians are able to afford their loan payments no matter what specialty they practice, what they are paid, or where they live.Medical education, while expensive, remains the good investment. An MD degree can lead to a lifetime of personal fulfillment and societal contributions. Everyone, with rare exceptions, accepted to a U.S. medical school will be able to finance their medical education via a path that aligns with their personal values and priorities.

  4. The North American Free Trade Agreement. Headline Series No. 299.

    Science.gov (United States)

    Grayson, George W.

    This document discusses the North American Free Trade Agreement (NAFTA) as a debate over the wisdom of opening the southern United States border to the free flow of goods and services between the United States and Mexico. The book is divided into six chapters. The first is a basic introduction to the development of the idea of a free trade…

  5. FUZZY DECISION MAKING MODEL FOR BYZANTINE AGREEMENT

    Directory of Open Access Journals (Sweden)

    S. MURUGAN

    2014-04-01

    Full Text Available Byzantine fault tolerance is of high importance in the distributed computing environment where malicious attacks and software errors are common. A Byzantine process sends arbitrary messages to every other process. An effective fuzzy decision making approach is proposed to eliminate the Byzantine behaviour of the services in the distributed environment. It is proposed to derive a fuzzy decision set in which the alternatives are ranked with grade of membership and based on that an appropriate decision can be arrived on the messages sent by the different services. A balanced decision is to be taken from the messages received across the services. To accomplish this, Hurwicz criterion is used to balance the optimistic and pessimistic views of the decision makers on different services. Grades of membership for the services are assessed using the non-functional Quality of Service parameters and have been estimated using fuzzy entropy measure which logically ranks the participant services. This approach for decision making is tested by varying the number of processes, varying the number of faulty services, varying the message values sent to different services and considering the variation in the views of the decision makers about the services. The experimental result shows that the decision reached is an enhanced one and in case of conflict, the proposed approach provides a concrete result, whereas decision taken using the Lamport’s algorithm is an arbitrary one.

  6. A shared " passengers & goods " city logistics system

    OpenAIRE

    2012-01-01

    International audience; Many strategic planning models have been developed to help decision making in city logistics. Such models do not take into account, or very few, the flow of passengers because the considered unit does not have the same nature (a person is active and a good is passive). However, it seems fundamental to gather the goods and the passengers in one model when their respective transports interact with each other. In this context, we suggest assessing a shared passengers & go...

  7. Foreign Affiliate Sales and Trade in Both Goods and Services

    OpenAIRE

    Chunding Li; John Whalley; Yan Chen

    2010-01-01

    Because of the differing forms that international agreements on trade in goods and trade in services take in the GATT (1994) and the GATS there is an incompatibility between measures of world trade in goods and services. Measures of goods trade reflecting GATT (1994) are restricted to trade that crosses borders. Service trade, however, under GATS mode 3 (commercial presence) includes both cross border delivery and foreign affiliate sales within borders. As a result, present comparisons of ser...

  8. Inter-observer agreement in the assessment of endoscopic findings in ulcerative colitis

    Directory of Open Access Journals (Sweden)

    de Lange Thomas

    2004-05-01

    Full Text Available Abstract Background Endoscopic findings are essential in evaluating the disease activity in ulcerative colitis. The aim of this study was to evaluate how endoscopists assess individual endoscopic features of mucosal inflammation in ulcerative colitis, the inter-observer agreement, and the importance of the observers' experience. Methods Five video clips of ulcerative colitis were shown to a group of experienced and a group of inexperienced endoscopists. Both groups were asked to assess eight endoscopic features and the overall mucosal inflammation on a visual analogue scale. The following statistical analyses were used; Contingency tables analysis, kappa analysis, analysis of variance, Pearson linear correlation analysis, general linear models, and agreement analysis. All tests were carried out two-tailed, with a significance level of 5%. Results The inter-observer agreement ranged from very good to moderate in the experienced group and from very good to fair in the inexperienced group. There was a significantly better inter-observer agreement in the experienced group in the rating of 6 out of 9 features (p A correlation was seen between all the observed endoscopic features in both groups of endoscopists. Among experienced endoscopists, a set of four endoscopic variables ("Vascular pattern", "Erosions", "Ulcerations" and Friability" explained 92% of the variation in EAI. By including "Granularity" in these set 91% of the variation in EAI was explained in the group of inexperienced endoscopists. Conclusion The inter-observer agreement in the rating of endoscopic features characterising ulcerative colitis is satisfactory in both groups of endoscopists but significantly higher in the experienced group. The difference in the mean score between the two groups is only significant for "ulcerations". The endoscopic variables "Vascular pattern", "Erosions", "Ulcerations" and Friability" explained the overall endoscopic activity index. Even though the

  9. 76 FR 20668 - Notice of Agreements Filed

    Science.gov (United States)

    2011-04-13

    ... amendment deletes Hanjin Shipping as a party to the Agreement. Agreement No.: 012105-001. Title: SCM Lines Transportes/CCNI Agreement. Parties: Compania Chilena de Navegacion Interoceanica S.A. and SCM...

  10. 75 FR 66098 - Notice of Agreements Filed

    Science.gov (United States)

    2010-10-27

    .... Agreement No.: 012067-003. Title: U.S. Supplemental Agreement to HLC Agreement. Parties: BBC Chartering & Logistics GmbH & Co. KG; Beluga Chartering GmbH; Chipolbrok; Clipper Project Ltd.; Hyndai Merchant Marine Co...

  11. 77 FR 12304 - Notice of Agreements Filed

    Science.gov (United States)

    2012-02-29

    ... . Agreement No.: 012067-005. Title: U.S. Supplemental Agreement to HLC Agreement. Parties: BBC Chartering & Logistics GmbH & Co. KG; Beluga Chartering GmbH; Chipolbrok; Clipper Project Ltd.; Hyndai Merchant Marine Co...

  12. 77 FR 72349 - Notice of Agreements Filed

    Science.gov (United States)

    2012-12-05

    ... . Agreement No.: 011707-009. Title: Gulf/South America Discussion Agreement. Parties: BBC Chartering... amendment removes BBC Chartering & Logistic GMBH & Co. KG as a party to the agreement. By Order of the...

  13. 78 FR 48163 - Notice of Agreements Filed

    Science.gov (United States)

    2013-08-07

    ..., Oregon as member to the agreement. Agreement No.: 012184-001. Title: Crowley/Maersk Line Panama--U.S. Space Charter Agreement. Parties: Crowley Latin America Services, LLC and A.P. Moller-Maersk A/S....

  14. 77 FR 45610 - Notice of Agreement Filed

    Science.gov (United States)

    2012-08-01

    ... (202) 523-5793 or tradeanalysis@fmc.gov . Agreement No.: 012125-001. Title: Maersk/Evergreen Slot Exchange Agreement. Parties: A.P. Moller-Maersk A/S and Evergreen Line Joint Service Agreement....

  15. 77 FR 32115 - Notice of Agreements Filed

    Science.gov (United States)

    2012-05-31

    ... Agreement Western Mediterranean-U.S. East Coast. Parties: CMA CGM, S.A. and A.P. Moller-Maersk A/S. Filing.... Synopsis: The amendment would add Morocco to the geographic scope of the agreement. Agreement No.:...

  16. 'The Good Citizen’

    DEFF Research Database (Denmark)

    Offersen, Sara Marie Hebsgaard; Vedsted, Peter; Andersen, Rikke Sand

    2017-01-01

    This article explores how healthcare-seeking practices and the transformation of bodily sensations into symptoms are embedded in what we term a ‘moral sensescape’ of ev- eryday life. Based on fi eldwork in a suburban middle-class neighbourhood in Denmark, we discuss how a moral relation between...... the Danish welfare state and the middle-class popula- tion is embodied in a responsibility for individual health. Overall, we identify a striving to be a ‘good citizen’; this entails confl icting moral possibilities in relation to experiencing, interpreting and acting on bodily sensations. We examine how......; this challenge constitutes complex navigational routes through the moral sensescape of the Danish middle...

  17. 'Good Order and Police'

    DEFF Research Database (Denmark)

    2016-01-01

    The emergence of police ordinances and police authorities in the early modern period has traditionally been seen as a way to discipline society in order to increase the power of the absolutist state. However, recent investigations of early modern policing in German and French regions show...... that ‘good order and police’ was in demand by the subjects and also adapted to local needs. Inspired by this research this article investigates the enforcement of police ordinances in the market towns of Aalborg and Sæby and the country district of Børglum-Jerslev. The results show that policing remained...... focused on local needs even after the creation of a royal police office in 1682. Policing mainly concerned the welfare and privileges of burghers in market towns until the introduction of a country police in 1791, when agrarian reforms began to erode the patriarchal order in the countryside. As a new way...

  18. The Social Dynamics of Art Research: Contemporary Photography in Belfast Post the Good Friday Agreement

    Science.gov (United States)

    Tuck, Sarah

    2014-01-01

    This article reflects critically on "The Social Dynamics of Art Research: Contemporary Photography in Belfast", an engaged research project conducted with photographers, community activists, academics and visual artists in Belfast. Through a critical examination of the project's theoretical architecture and methodological framework this…

  19. The Social Dynamics of Art Research: Contemporary Photography in Belfast Post the Good Friday Agreement

    Science.gov (United States)

    Tuck, Sarah

    2014-01-01

    This article reflects critically on "The Social Dynamics of Art Research: Contemporary Photography in Belfast", an engaged research project conducted with photographers, community activists, academics and visual artists in Belfast. Through a critical examination of the project's theoretical architecture and methodological framework this…

  20. The State Authorization Reciprocity Agreement (SARA): A Good Idea Whose Time Has Come

    Science.gov (United States)

    Longanecker, David; Hill, Marshall A.

    2014-01-01

    In this article the authors argue that states need a new way to oversee the delivery of postsecondary distance education across state borders. They assert that the current process is too spotty to assure consistent consumer protection and too cumbersome and expensive for institutions. Because education is not specified in the US Constitution as a…

  1. Good agreement between minimal erythema dose test reactions and objective measurements

    DEFF Research Database (Denmark)

    Bodekær, Mette; Philipsen, Peter Alshede; Karlsmark, Tonny

    2013-01-01

    The erythema resulting from the minimal erythema dose (MED) test is subjectively assessed. The evaluator visually grades erythema on an ordinal scale. Both intra- and interobserver variation have been found for this erythema assessment. We wanted to examine if objective measurements could be used...

  2. Known Good Substrates Year 1

    Science.gov (United States)

    2007-12-05

    Monotonic Decrease of VC-VSi, SN1, and SN2 with ↑ ρ (↓ [N])” Known Good Substrates Contractor: Dow Corning Corporation Contract No. N00014-05-C-0324...Vapor Transport (CVT). The key essence of the CVT approach is to control the growth process by strategic controlled chemical reactions of the source...efficacy for its use in 4H n+ SiC crystal growth. The approach consists of the following steps: • Reaction cell design/modeling and chemical

  3. The Australia–US Free Trade Agreement - An Assessment

    OpenAIRE

    Philippa Dee

    2005-01-01

    Australia and the United States signed a bilateral trade agreement in 2004. This paper analyses the provisions of the agreement, compares the provisions with other bilateral and multilateral agreements and comments on the modelling that the Australian Government used to estimate the likely benefits of the agreement. The author concludes that the modelling relied on overstates the potential gains from the agreement, which establishes many undesirable precedents, especially in relation to sugar...

  4. Terms of Trade and Global Efficiency Effects of Free Trade Agreements, 1990-2002

    OpenAIRE

    Anderson, James; Yotov, Yoto

    2012-01-01

    This paper infers the terms of trade effects of the Free Trade Agreements (FTAs) of the 1990s. Using panel data methods to resolve two way causality between trade and FTAs, we estimate large FTA effects on bilateral trade volume in digit manufacturing goods from 1990-2002. We deduce the terms of trade changes implied by these volume effects for 40 countries plus a rest-of-the-world aggregate using the structural gravity model. Some countries gain over 10%, some lose less than 0.2%. Overall, u...

  5. Good Governance in Public Procurement: A South African Case Study

    Directory of Open Access Journals (Sweden)

    R Roos

    2008-08-01

    Full Text Available In this article good governance in public procurement, with particular reference to accountability is discussed. The principle of providing adequate remedies in public procurement is put under the spotlight. This is done with reference to the decision in Steenkamp NO v Provincial Tender Board, Eastern Cape. In this case the Constitutional Court had to consider whether an initially successful tenderer could lodge a delictual claim for damages to compensate for expenses incurred after conclusion of a contract, which was subsequently rendered void on an application for review of the tender award. The applicable principles of good governance and the applicable provisions of the UNCITRAL Model Law on Public Procurement and the WTO plurilateral Government Procurement Agreement are analysed. This is done to enable an evaluation of the decision by the Constitutional Court in the above case. It is concluded that the South African public procurement system does in this instance comply with the basic principles of good governance with regard to accountability.

  6. The General Unenforceability of Collective Agreements under Nigerian Labour Jurisprudence: The Paradox of Agreement without Agreement

    Directory of Open Access Journals (Sweden)

    Vincent Iwunze

    2013-12-01

    Full Text Available This study considers the status of collective agreements under Nigerian labour law, examining the extent of their enforceability under the extant laws. It considers the emerging trends in some more advanced jurisdictions of the world in that regard and comparatively portrays the anachronisms of the Nigerian law on the point. It takes the position that the current legal climate as regards the legal status of collective agreements under Nigerian law is potentially disruptive of industrial peace and harmony and is bound to occasion serious hardship on employees. The work suggests among others a jurisprudential shift in paradigm if the Nigerian labour jurisprudence must meet and be reflective of modern socio-economic realities.

  7. Eggs: good or bad?

    Science.gov (United States)

    Griffin, Bruce A

    2016-08-01

    Eggs have one of the lowest energy to nutrient density ratios of any food, and contain a quality of protein that is superior to beef steak and similar to dairy. From a nutritional perspective, this must qualify eggs as 'good'. The greater burden of proof has been to establish that eggs are not 'bad', by increasing awareness of the difference between dietary and blood cholesterol, and accumulating sufficient evidence to exonerate eggs from their associations with CVD and diabetes. After 60 years of research, a general consensus has now been reached that dietary cholesterol, chiefly from eggs, exerts a relatively small effect on serum LDL-cholesterol and CVD risk, in comparison with other diet and lifestyle factors. While dietary guidelines have been revised worldwide to reflect this view, associations between egg intake and the incidence of diabetes, and increased CVD risk in diabetes, prevail. These associations may be explained, in part, by residual confounding produced by other dietary components. The strength of evidence that links egg intake to increased CVD risk in diabetes is also complicated by variation in the response of serum LDL-cholesterol to eggs and dietary cholesterol in types 1 and 2 diabetes. On balance, the answer to the question as to whether eggs are 'bad', is probably 'no', but we do need to gain a better understanding of the effects of dietary cholesterol and its association with CVD risk in diabetes.

  8. Good Enough to Teach?

    DEFF Research Database (Denmark)

    Denver, Louise; Jensen, Christian; Mees, Inger

    2016-01-01

    In a study conducted at the Copenhagen Business School, 1,794 students completed questionnaires on lectures given by 31 non-native English-speaking lecturers in 12 EMI programmes. They were asked to rate the lecture, the lecturer and the lecturer’s language. Statistical analyses revealed a correl......In a study conducted at the Copenhagen Business School, 1,794 students completed questionnaires on lectures given by 31 non-native English-speaking lecturers in 12 EMI programmes. They were asked to rate the lecture, the lecturer and the lecturer’s language. Statistical analyses revealed...... a correlation between the students’ perceptions of the lecturers’ general lecturing competence (defined as knowledge of subject and teaching skills) and their perceptions of their English language proficiency (Jensen et al. 2013). In return for their assistance, each lecturer received a feedback sheet on how...... whose L1 was Danish. An examination of the tutors’ comments showed that they could be divided into two main categories: formal language skills and pragmatic or metadiscursive features. The observations on language features are presented using a slightly adapted version of Lavelle’s (2008) “good...

  9. HIV treatment as prevention: principles of good HIV epidemiology modelling for public health decision-making in all modes of prevention and evaluation.

    Directory of Open Access Journals (Sweden)

    Wim Delva

    Full Text Available Public health responses to HIV epidemics have long relied on epidemiological modelling analyses to help prospectively project and retrospectively estimate the impact, cost-effectiveness, affordability, and investment returns of interventions, and to help plan the design of evaluations. But translating model output into policy decisions and implementation on the ground is challenged by the differences in background and expectations of modellers and decision-makers. As part of the PLoS Medicine Collection "Investigating the Impact of Treatment on New HIV Infections"--which focuses on the contribution of modelling to current issues in HIV prevention--we present here principles of "best practice" for the construction, reporting, and interpretation of HIV epidemiological models for public health decision-making on all aspects of HIV. Aimed at both those who conduct modelling research and those who use modelling results, we hope that the principles described here will become a shared resource that facilitates constructive discussions about the policy implications that emerge from HIV epidemiology modelling results, and that promotes joint understanding between modellers and decision-makers about when modelling is useful as a tool in quantifying HIV epidemiological outcomes and improving prevention programming.

  10. Volatility Spillovers in Capesize Forward Freight Agreement Markets

    Directory of Open Access Journals (Sweden)

    Xiaoxing Gong

    2016-01-01

    Full Text Available This paper is to investigate spillovers in the Capesize forward freight agreements (FFAs markets before and after the global financial crisis. The paper chooses four Capesize voyage routes FFAs (C3, C4, C5, and C7, two time-charter routes FFAs (BCIT/C average, BPI T/C average, and spot rates as research subjects, covering the periods 3 January 2006 to 24 December 2015. This paper applies Volatility Spillover Multivariate Stochastic Volatility (VS-MSV model to analyze volatility spillover effects and estimates the parameters via software of Bayesian inference using Gibbs Sampling (BUGS, the deviance information criterion (DIC used for goodness-of-fit model. The results suggest that there are volatility spillover effects in certain Capesize FFAs routes, and the effects from spot rates to FFAs take place before crisis, yet they are bilateral after crisis. With the development of shipping markets, the correlations between FFAs and spot rate are enhanced, and it seems that the effects depend on market information and traders’ behavior. So practitioners could make decisions according to the spillovers.

  11. Avoiding or restricting defectors in public goods games?

    Science.gov (United States)

    Han, The Anh; Pereira, Luís Moniz; Lenaerts, Tom

    2015-02-06

    When creating a public good, strategies or mechanisms are required to handle defectors. We first show mathematically and numerically that prior agreements with posterior compensations provide a strategic solution that leads to substantial levels of cooperation in the context of public goods games, results that are corroborated by available experimental data. Notwithstanding this success, one cannot, as with other approaches, fully exclude the presence of defectors, raising the question of how they can be dealt with to avoid the demise of the common good. We show that both avoiding creation of the common good, whenever full agreement is not reached, and limiting the benefit that disagreeing defectors can acquire, using costly restriction mechanisms, are relevant choices. Nonetheless, restriction mechanisms are found the more favourable, especially in larger group interactions. Given decreasing restriction costs, introducing restraining measures to cope with public goods free-riding issues is the ultimate advantageous solution for all participants, rather than avoiding its creation.

  12. 12 CFR 614.4345 - Guaranty agreements.

    Science.gov (United States)

    2010-01-01

    ...-Sharing Agreements § 614.4345 Guaranty agreements. Guaranty agreements under which a percentage of the risk associated with specific loans is assumed may be entered into by or among System banks and... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Guaranty agreements. 614.4345 Section 614.4345...

  13. 25 CFR 163.71 - Agreement funding.

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Agreement funding. 163.71 Section 163.71 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER GENERAL FORESTRY REGULATIONS Cooperative Agreements § 163.71 Agreement funding. In cooperative agreements, the Secretary is authorized to advance...

  14. 7 CFR 947.111 - Marketing agreement.

    Science.gov (United States)

    2010-01-01

    ... Definitions § 947.111 Marketing agreement. Marketing agreement means Marketing Agreement No. 114, as amended. ... 7 Agriculture 8 2010-01-01 2010-01-01 false Marketing agreement. 947.111 Section 947.111 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE...

  15. 75 FR 6397 - Notice of Agreements Filed

    Science.gov (United States)

    2010-02-09

    ....gov . Agreement No.: 011346-019. Title: Israel Trade Conference Agreement. Parties: A.P. Moller-Maersk A/S; Maersk Line Limited; and Zim Integrated Shipping Services, Ltd. Filing Party: Howard A. Levy...: The amendment adds American President Lines, Ltd. as a party to the agreement. Agreement No.:...

  16. 78 FR 33840 - Notice of Agreements Filed

    Science.gov (United States)

    2013-06-05

    ... (202)-523-5793 or tradeanalysis@fmc.gov . Agreement No.: 012037-005. Title: Maersk Line/CMA CGM...-003. Title: The World Liner Data Agreement. Parties: ANL Container Line Pty Ltd.; A.P. Moller-Maersk A.... Agreement No.: 012209. Title: APL/Maersk Line Slot Charter Agreement. Parties: American President Lines,...

  17. 75 FR 82025 - Notice of Agreements Filed

    Science.gov (United States)

    2010-12-29

    ... amendment updates the corporate addresses of APL and Hyundai. Agreement No.: 011928-005. Title: Maersk Line... Line Vessel Sharing Agreement. Parties: Hamburg-Sud and A.P. Moeller-Maersk A/S. Filing Party: Wayne... services under the agreement. Agreement No.: 012057-005. Title: CMA CGM/Maersk Line Space Charter,...

  18. 77 FR 1689 - Notice of Agreements Filed

    Science.gov (United States)

    2012-01-11

    ... Vietnam. Agreement No.: 012151. Title: Maersk Line/MSC WCCA Space Charter Agreement. Parties: A.P. Moller-Maersk A/S and MSC Mediterranean Shipping Company, S.A. Filing Party: Wayne R. Rohde, Esquire; Cozen O... . Agreement No.: 012150. Title: COSCON/POS Space Charter and Sailing Agreement. Parties: COSCO Container...

  19. 77 FR 61751 - Notice of Agreements Filed

    Science.gov (United States)

    2012-10-11

    ... restates the Agreement. Agreement No.: 012184-000. Title: Crowley/Maersk Line Panama-U.S. Space Charter Agreement. Parties: Crowley Latin America Services, LLC and A.P. Moller-Maersk A/S Filing Party: Wayne R... agreement authorizes Crowley to charter space to Maersk Line in the trade from Panama to the U.S....

  20. 7 CFR 1415.17 - Cooperative agreements.

    Science.gov (United States)

    2010-01-01

    ... the “right of enforcement” clause to read as set forth in the GRP cooperative agreement. This right is... 7 Agriculture 10 2010-01-01 2010-01-01 false Cooperative agreements. 1415.17 Section 1415.17... Cooperative agreements. (a) NRCS may enter into cooperative agreements which establish terms and...

  1. 23 CFR 140.606 - Project agreements.

    Science.gov (United States)

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Project agreements. 140.606 Section 140.606 Highways... Reimbursement for Bond Issue Projects § 140.606 Project agreements. Project Agreements, Form PR-2, shall be prepared and executed. Agreement provision 8 on the reverse side of Form PR-2 1 shall apply for bond issue...

  2. Supplier Performance Monitoring and Improvement (SPMI through SIPOC Analysis and PDCA Model to the ISO 9001 QMS in Sports Goods Manufacturing Industry

    Directory of Open Access Journals (Sweden)

    2011-12-01

    Full Text Available Background: Increasing global competition and customer expectations are forcing companies to improve their supplier performance as part of their supply chain governance initiative. A sport goods manufacturing industry is intensive supplier base industry and majority of these comes under small medium enterprises with limited resources. Developing an easy - deploy, cost effective and result oriented frame work for this industry is a critical business competency. Methods: This paper lays out a framework - a "standard operating system" - for continuous supplier performance monitoring and improvement (SPMI and is composed of following sections. In the first section supplier performance monitoring and improvement is overviewed with its basic concepts, and then improvement methods used in the paper are explained based on literature review. The third and fourth section focus on the methodology, explaining the way of SIPOC Analysis and PDCA application with using ISO 9001; 2008 QMS standards and example showing its results. Results: The existing process of Supplier Performance Monitoring and Improvement (SPMI was defined and mapped and then analyzed and revised through SIPOC Analysis by incorporating to PDCA Cycle and ISO 9001 QMS to identify problem areas, variations and unnecessary activities. Corrective actions were recommended to deal with problem areas and an improved and revised Supplier Performance Monitoring and Improvement (SPMI Process is suggested. Conclusions: Every organization needs to use a proper combination and selection of quality tools, methodologies and techniques for implementing continuous quality improvement process. This framework will provide a guidance for anyone who wants to develop supplier performance measurement system in sports goods manufacturing industry and other small - medium enterprises.

  3. Good old days?

    OpenAIRE

    Greenberg, Charles J

    2005-01-01

    Alternative models of subsidizing scholarly publishing and dissemination have germinated and gathered momentum in the fertile soil of dissatisfaction. Like the stubborn spring dandelion that needs but a small crack in the sidewalk to flower boldly, the first flowers of Open Access in library literature, including Biomedical Digital Libraries, have sensed their opportunity to change the existing paradigm of giving away our scholarship and intellectual property, only to buy it back for the priv...

  4. Rule by Good People

    DEFF Research Database (Denmark)

    Funahashi, Daena

    2016-01-01

    This article rethinks the presumed translatability of the World Health Organization’s (WHO) health promotion models and explores the unintended consequences of their global export. Specifically, I focus on the Thai military government’s adoption (2006–2008) of the Health in All Policies (Hi......, and explore the effect that global health movements have on the status of political legitimacy and national political conflicts....

  5. Can the Paris Agreement stop global warming?

    DEFF Research Database (Denmark)

    Howalt Owe, Selina; Pedersen, Jens Olaf Pepke

    in the year 2030 of about 55 Gt Carbon to 40 Gt Carbon. This can be compared to an approximate emission of 35 Gt in 2014 and thus means that a global rise in emission of only 5 Gt Carbon is allowed over the next 15 years Using the Danish Center for Earth System Science (DCESS)model [1] we have investigated...... how large an emission reduction is necessary to keep the global temperatures below these targets.The DCESS model is a low order Earth system box model which includes atmosphere, ocean, ocean sediment, land biosphere and lithosphere components, and using the year 1765 as the preindustriallevel. We have...... examined different emission scenarios and the national commitments and find that even if the Paris Agreement is fulfilled, global temperatures will have increased by 1.5 degree C in 2030, and then only a yearly percentage reduction of 5% or more will be sufficient to keep temperatures below 2 degree C...

  6. Precaution, law and principles of good administration.

    Science.gov (United States)

    Fisher, E

    2005-01-01

    The precautionary principle is a legal principle concerned with the process of how decisions are made. In implementing and interpreting it regard must be had to the surrounding legal culture and in particular the principles of good administration in operation. Highlighting those principles emphasises that within a particular jurisdiction there is often very little agreement over their nature. Within the European Union contradictory principles are the product of: assumptions about risk problem-solving, the ambiguous nature of European administration, a concern with accountability in the face of recent food controversies, and the impact of international trade rules. These contradictory principles present a number of challenges for implementing the precautionary principle.

  7. Being Good by Doing Good: Goodness and the Evaluation of Persons

    NARCIS (Netherlands)

    Schmidt, Andreas

    2017-01-01

    Does doing good in itself make one a better person? This idea is intuitive yet its precise formulation underexplored. This article first shows that it is not the case that a person is good to the extent that her existence brings about good or to the extent that her actions do good. A proportional pr

  8. Good Looking Is Looking Good / Märt Milter

    Index Scriptorium Estoniae

    Milter, Märt

    1998-01-01

    Meloodilist drum ǹ̀bassi viljelevatest välismaa plaadifirmadest Good Looking Recordsist ja Looking Good Recordsist, mida juhib LTJ Bukem ja temaga koostööd tegevatest muusikutest Blame, Seba, Tayla, MC Conrad, Artemis

  9. Good Looking Is Looking Good / Märt Milter

    Index Scriptorium Estoniae

    Milter, Märt

    1998-01-01

    Meloodilist drum ǹ̀bassi viljelevatest välismaa plaadifirmadest Good Looking Recordsist ja Looking Good Recordsist, mida juhib LTJ Bukem ja temaga koostööd tegevatest muusikutest Blame, Seba, Tayla, MC Conrad, Artemis

  10. Between voluntary agreement and legislation

    DEFF Research Database (Denmark)

    Gwozdz, Wencke; Hedegaard, Liselotte; Reisch, Lucia

    2009-01-01

    Voluntary agreements and self-imposed standards are broadly applied to restrict the influence food advertising exerts on children’s food choices – yet their effects are unknown. The current project will therefore investigate whether and, if yes, how the Danish Code for Responsible Food Marketing...... Communication towards Children (hereafter: CODE) – with its dependence on a supportive institutional environment and acceptance of as well as dynamics between involved key stakeholders like consumers, political actors and firms – contributes to fighting the obesity pandemic.Thus, we explore within this article...... what information about the process of implementing the CODE as well as about the evolved dynamics between key stakeholders is already available. Here, the recently published report of the PolMark project sheds light on the dynamics between the key stakeholders in relation to the current Danish...

  11. Energy conservation agreement; Avtale enoek

    Energy Technology Data Exchange (ETDEWEB)

    Helgerud, H.E.; Alm, L.K.; Moeller, H.M.; Finden, P.

    1996-12-01

    The report analyses the possibilities and approaches on the use of energy conservation agreements as a means between the authorities and the industry in Norway, and a particular attention is laid on the connection between energy consumption and CO{sub 2} discharges both nationally and internationally. The authorities define energy conservation as an efficient socio-economic use of energy, and the industrial branch within processing defines the same as an energy saving measure giving positive environmental effects. The study is connected to stationary energy use, and which includes CO{sub 2} discharges. The stationary energy consumption is about 52 TWh/year, and the thermal energy use within the branch contributes to an annual CO{sub 2} discharge of about 4.65 million tons, or 13% of the total CO{sub 2} discharge in Norway (values from 1993). 29 refs., 3 figs., 6 tabs.

  12. Modeling the Differences in Biochemical Capabilities of Pseudomonas Species by Flux Balance Analysis: How Good Are Genome-Scale Metabolic Networks at Predicting the Differences?

    Directory of Open Access Journals (Sweden)

    Parizad Babaei

    2014-01-01

    Full Text Available To date, several genome-scale metabolic networks have been reconstructed. These models cover a wide range of organisms, from bacteria to human. Such models have provided us with a framework for systematic analysis of metabolism. However, little effort has been put towards comparing biochemical capabilities of closely related species using their metabolic models. The accuracy of a model is highly dependent on the reconstruction process, as some errors may be included in the model during reconstruction. In this study, we investigated the ability of three Pseudomonas metabolic models to predict the biochemical differences, namely, iMO1086, iJP962, and iSB1139, which are related to P. aeruginosa PAO1, P. putida KT2440, and P. fluorescens SBW25, respectively. We did a comprehensive literature search for previous works containing biochemically distinguishable traits over these species. Amongst more than 1700 articles, we chose a subset of them which included experimental results suitable for in silico simulation. By simulating the conditions provided in the actual biological experiment, we performed case-dependent tests to compare the in silico results to the biological ones. We found out that iMO1086 and iJP962 were able to predict the experimental data and were much more accurate than iSB1139.

  13. Scales of degree of facial paralysis: analysis of agreement

    Directory of Open Access Journals (Sweden)

    Kércia Melo de Oliveira Fonseca

    2015-06-01

    Full Text Available INTRODUCTION: It has become common to use scales to measure the degree of involvement of facial paralysis in phonoaudiological clinics. OBJECTIVE: To analyze the inter- and intra-rater agreement of the scales of degree of facial paralysis and to elicit point of view of the appraisers regarding their use. METHODS: Cross-sectional observational clinical study of the Chevalier and House & Brackmann scales performed by five speech therapists with clinical experience, who analyzed the facial expression of 30 adult subjects with impaired facial movements two times, with a one week interval between evaluations. The kappa analysis was employed. RESULTS: There was excellent inter-rater agreement for both scales (kappa > 0.80, and on the Chevalier scale a substantial intra-rater agreement in the first assessment (kappa = 0.792 and an excellent agreement in the second assessment (kappa = 0.928. The House & Brackmann scale showed excellent agreement at both assessments (kappa = 0.850 and 0.857. As for the appraisers' point of view, one appraiser thought prior training is necessary for the Chevalier scale and, four appraisers felt that training is important for the House & Brackmann scale. CONCLUSION: Both scales have good inter- and intra-rater agreement and most of the appraisers agree on the ease and relevance of the application of these scales.

  14. Good old days?

    Science.gov (United States)

    Greenberg, Charles J

    2005-04-13

    Alternative models of subsidizing scholarly publishing and dissemination have germinated and gathered momentum in the fertile soil of dissatisfaction. Like the stubborn spring dandelion that needs but a small crack in the sidewalk to flower boldly, the first flowers of Open Access in library literature, including Biomedical Digital Libraries, have sensed their opportunity to change the existing paradigm of giving away our scholarship and intellectual property, only to buy it back for the privilege of knowing it can be read. Will biomedical digital library and informatics researchers understand their role in a new era of Open Access simply by desiring an immediate uninhibited global audience and recognizing the necessity of open access peer-reviewed literature to become self-sufficient?

  15. The Varieties of Good Design

    DEFF Research Database (Denmark)

    Ylirisku, Salu; Arvola, Mattias

    2017-01-01

    This chapter explores the philosopher and logician Georg Henrik von Wright’s metaethical treatise of the varieties of goodness in the context of design. von Wright investigated the use of notion of ‘good’ in language, and he identified six kinds of goodness: namely utilitarian goodness, instrumen......This chapter explores the philosopher and logician Georg Henrik von Wright’s metaethical treatise of the varieties of goodness in the context of design. von Wright investigated the use of notion of ‘good’ in language, and he identified six kinds of goodness: namely utilitarian goodness...

  16. How to make a good animation: A grounded cognition model of how visual representation design affects the construction of abstract physics knowledge

    Science.gov (United States)

    Chen, Zhongzhou; Gladding, Gary

    2014-06-01

    Visual representations play a critical role in teaching physics. However, since we do not have a satisfactory understanding of how visual perception impacts the construction of abstract knowledge, most visual representations used in instructions are either created based on existing conventions or designed according to the instructor's intuition, which leads to a significant variance in their effectiveness. In this paper we propose a cognitive mechanism based on grounded cognition, suggesting that visual perception affects understanding by activating "perceptual symbols": the basic cognitive unit used by the brain to construct a concept. A good visual representation activates perceptual symbols that are essential for the construction of the represented concept, whereas a bad representation does the opposite. As a proof of concept, we conducted a clinical experiment in which participants received three different versions of a multimedia tutorial teaching the integral expression of electric potential. The three versions were only different by the details of the visual representation design, only one of which contained perceptual features that activate perceptual symbols essential for constructing the idea of "accumulation." On a following post-test, participants receiving this version of tutorial significantly outperformed those who received the other two versions of tutorials designed to mimic conventional visual representations used in classrooms.

  17. 奢侈品在线销售的信任模式探究%Trust Model Exploration on Online Sales of Luxury Goods

    Institute of Scientific and Technical Information of China (English)

    从静

    2011-01-01

    奢侈品最令人称道之处是其创造新市场的功能。在货源最为吃紧的奢侈品市场上,中国的电子商务网站正在尝试搭建全球供应链体系。但在线销售的奢侈品的信任度是否有所降低?零售实体店的豪华购物体验能够在因特网上成功复制吗?文章对此进行了探讨。%Luxury is most renowned for its capabilities to create new markets.In the tight supply of the most luxury market,China is trying to build e-commerce site global supply chain system.However,online sales of luxury goods is reduced trust? Luxury retail store on the Internet shopping experience can be successfully replicated? This paper explores about this.

  18. Lassen's equation is a good approximation of permeability-surface model: new α values for ⁹⁹mTc-HMPAO and ⁹⁹mTc-ECD.

    Science.gov (United States)

    Kameyama, Masashi

    2014-07-01

    Brain perfusion tracers like [(99m)Tc] d,l-hexamethyl-propyeneamine oxime ((99m)Tc-HMPAO) and [(99m)Tc] ethyl-cysteinate dimer ((99m)Tc-ECD) underestimate regional cerebral blood flow (rCBF) at high flow values. To improve linearity between tracer accumulation and rCBF, two different models have been proposed. One is Lassen's correction algorithm for back-diffusion of tracer, and the other is based on the permeability-surface (PS) model for correction of low first-pass extraction. Although both these models have the same goal, they have completely different forms of equation. It was demonstrated that mathematical approximation of the PS model equation leads to Lassen's equation. In this process, the relationship between PS, CBF values and Lassen's parameter was acquired, and how to correct both the back-diffusion and low first-pass extraction was also demonstrated. A computer simulation confirmed that the two models provided similar consequences when the parameter value is chosen according to the relationship found. Lassen's equation can be used to correct not only back-diffusion but also low first-pass extraction. To perform overall correction, the parameter value we have been using for decades may be too weak. I estimated that the parameter value for overall correction of HMPAO would be around 0.5, and that of ECD would be around 0.65.

  19. Good governance for pension schemes

    CERN Document Server

    Thornton, Paul

    2011-01-01

    Regulatory and market developments have transformed the way in which UK private sector pension schemes operate. This has increased demands on trustees and advisors and the trusteeship governance model must evolve in order to remain fit for purpose. This volume brings together leading practitioners to provide an overview of what today constitutes good governance for pension schemes, from both a legal and a practical perspective. It provides the reader with an appreciation of the distinctive characteristics of UK occupational pension schemes, how they sit within the capital markets and their social and fiduciary responsibilities. Providing a holistic analysis of pension risk, both from the trustee and the corporate perspective, the essays cover the crucial role of the employer covenant, financing and investment risk, developments in longevity risk hedging and insurance de-risking, and best practice scheme administration.

  20. Multiwalled Carbon Nanotube Deposition on Model Environmental Surfaces

    Science.gov (United States)

    Deposition of multiwalled carbon nanotubes (MWNTs) on model environmental surfaces was investigated using a quartz crystal microbalance with dissipation monitoring (QCM-D). Deposition behaviors of MWNTs on positively and negatively charged surfaces were in good agreement with Der...

  1. Multiwalled Carbon Nanotube Deposition on Model Environmental Surfaces

    Science.gov (United States)

    Deposition of multiwalled carbon nanotubes (MWNTs) on model environmental surfaces was investigated using a quartz crystal microbalance with dissipation monitoring (QCM-D). Deposition behaviors of MWNTs on positively and negatively charged surfaces were in good agreement with Der...

  2. Observers' Agreement on Measurements in Fiberoptic Endoscopic Evaluation of Swallowing.

    Science.gov (United States)

    Pilz, Walmari; Vanbelle, Sophie; Kremer, Bernd; van Hooren, Michel R; van Becelaere, Tine; Roodenburg, Nel; Baijens, Laura W J

    2016-04-01

    This study analyzed the effect that dysphagia etiology, different observers, and bolus consistency might have on the level of agreement for measurements in FEES images reached by independent versus consensus panel rating. Sixty patients were included and divided into two groups according to dysphagia etiology: neurological or head and neck oncological. All patients underwent standardized FEES examination using thin and thick liquid consistencies. Two observers scored the same exams, first independently and then in a consensus panel. Four ordinal FEES variables were analyzed. Statistical analysis was performed using a linear weighted kappa coefficient and Bayesian multilevel model. Intra- and interobserver agreement on FEES measurements ranged from 0.76 to 0.93 and from 0.61 to 0.88, respectively. Dysphagia etiology did not influence observers' agreement level. However, bolus consistency resulted in decreased interobserver agreement for all measured FEES variables during thin liquid swallows. When rating on the consensus panel, the observers deviated considerably from the scores they had previously given on the independent rating task. Observer agreement on measurements in FEES exams was influenced by bolus consistency, not by dysphagia etiology. Therefore, observer agreement on FEES measurements should be analyzed by taking bolus consistency into account, as it might affect the interpretation of the outcome. Identifying factors that might influence agreement levels could lead to better understanding of the rating process and assist in developing a more precise measurement scale that would ensure higher levels of observer agreement for measurements in FEES exams.

  3. Modeling multiple land use changes using ANN, CART and MARS: Comparing tradeoffs in goodness of fit and explanatory power of data mining tools

    Science.gov (United States)

    Tayyebi, Amin; Pijanowski, Bryan C.

    2014-05-01

    Over half of the earth's terrestrial surface has been modified by humans. This modification is called land use change and its pattern is known to occur in a non-linear way. The land use change modeling community can advance its models using data mining tools. Here, we present three data mining land use change models, one based on Artificial Neural Network (ANN), another on Classification And Regression Trees (CART) and another Multivariate Adaptive Regression Splines (MARS). We reconfigured the three data mining models to concurrently simulate multiple land use classes (e.g. agriculture, forest and urban) in South-Eastern Wisconsin (SEWI), USA (time interval 1990-2000) and in Muskegon River Watershed (MRW), Michigan, USA (time interval 1978-1998). We compared the results of the three data mining tools using relative operating characteristic (ROC) and percent correct match (PCM). We found that ANN provided the best accuracy in both areas for three land use classes (e.g. urban, agriculture and forest). In addition, in both regions, CART and MARS both showed that forest gain occurred in areas close to current forests, agriculture patches and away from roads. Urban increased in areas of high urban density, close to roads and in areas with few forests and wetlands. We also found that agriculture gain is more likely for the areas closer to the agriculture and forest patches. Elevation strongly influenced urbanization and forest gain in MRW while it has no effect in SEWI.

  4. Good nutritional practice from producer to consumer.

    Science.gov (United States)

    Raspor, P; Jevsnik, M

    2008-03-01

    Today we manage food safety through good practices at different levels of food production, distribution, and consumption. The paper analyses current good practices, parameters involved in the food safety circle along the food supply chain, and consumer dilemmas. As a result of the current situation the new approach called "Good Nutritional Practice" (GNP) is proposed to balance the food safety systems. It is shown how important it is to integrate actual the food safety solutions within GNP, which includes consumers, and is based on a model that covers subsystems from other relevant good practices (nine good practices along the food supply chain). It has been shown that present maintenance of food safety in the food supply chain can be easily broken down, because of the different kinds of barriers or a simple misunderstanding among stakeholders including consumers.

  5. Some Remarks on Good Sets

    Indian Academy of Sciences (India)

    K Gowri Navada

    2004-11-01

    It is shown that (1) if a good set has finitely many related components, then they are full, (2) loops correspond one-to-one to extreme points of a convex set. Some other properties of good sets are discussed.

  6. Enabling Open Cloud Markets Through WS-Agreement Extensions

    Science.gov (United States)

    Risch, Marcel; Altmann, Jörn

    Research into computing resource markets has mainly considered the question of which market mechanisms provide a fair resource allocation. However, while developing such markets, the definition of the unit of trade (i.e. the definition of resource) has not been given much attention. In this paper, we analyze the requirements for tradable resource goods. Based on the results, we suggest a detailed goods definition, which is easy to understand, can be used with many market mechanisms, and addresses the needs of a Cloud resource market. The goods definition captures the complete system resource, including hardware specifications, software specifications, the terms of use, and a pricing function. To demonstrate the usefulness of such a standardized goods definition, we demonstrate its application in the form of a WS-Agreement template for a number of market mechanisms for commodity system resources.

  7. Inter-rater agreement in radiographic canine hip dysplasia evaluation.

    Science.gov (United States)

    Geissbühler, U; Drazovic, S; Lang, J; Howard, J

    2017-04-08

    The objective was to determine the agreement between scrutineers assessing canine hip dysplasia (CHD) within and between the Fédération Cynologique Internationale (FCI) and the Swiss (CH) grading schemes, and between first-opinion and second-opinion scrutineers using the CH scheme. 62 scrutineers, participating in a quality assessment programme, were asked to evaluate 12 sets of hip radiographs. All radiographs had been previously evaluated by a first-opinion and 7 by both a first-opinion and second-opinion scrutineers using the CH scheme. Inter-rater agreement (κ) and intraclass correlation (ICC) were evaluated for the Norberg angle and dysplasia grades, and ICC for the numerical CH scores. The κ and ICC were 0.290 and 0.471 for Norberg angles, 0.372 and 0.577 for FCI grades, and 0.417 and 0.567 for CH grades, respectively. The ICC for CH scores was 0.614. Total agreement for grades was found in a single case. For radiographs evaluated using both schemes, raters gave the same grade in 441 cases, a lower FCI than CH grade in 78 cases and a lower CH than FCI grade in 32 cases. Intrarater agreement between grades of the two schemes was 0.786. Agreement between the first-opinion and second-opinion scrutineers was 0.250 for Norberg angles and -0.286 for CH grades. Although agreement between the two schemes was good, agreement between scrutineers using either scheme was only fair to moderate, and no agreement was found between first-opinion and second-opinion scrutineers. Application of the FCI and CH schemes may impact the incidence of hip dysplasia in populations with both severe and moderate dysplasia, but is unlikely to impact populations with only mild dysplasia. The CH system of first-opinion and second-opinion examinations should be re-evaluated. British Veterinary Association.

  8. Do Someolle a Good Turn

    Institute of Scientific and Technical Information of China (English)

    程炜

    2000-01-01

    "You've done a number of favors for me," Brewster said,"so allow me to do you a good turn. Let me take you out to lunch today." Slightly dizzy, Brewster's friend agreed. He hadn't expected Brewster to do him a good turn. To do someone a good turn is to do something nice or helpful for someone.

  9. Good P rimary English Teachers Trained in “Trinity” Co-cultivation Model%“三位一体”协同培养卓越小学英语教师

    Institute of Scientific and Technical Information of China (English)

    冯冰清

    2016-01-01

    实施卓越教师培养计划,建立高校与地方政府、中小学“三位一体”协同培养新机制,是当前教师培养模式改革的热点。在讨论卓越教师内涵的基础上,以英语教育专业为例,提出了卓越小学英语教师培养教学改革具体措施,以期对卓越小学教师培养的教学改革提供些许启示。%It is a current focus of the reform of teacher training mode to initiate a good teacher cultivation project and to establish a co-cultivating model of a trinity of the college concerned, local government and primary and high schools. Based on the definition of a good teacher, this paper explores some practical measures of cultivating good teachers via the practice of English education in the hope of providing some suggestions for the teaching reform of good teacher training practice.

  10. 22 CFR 124.1 - Manufacturing license agreements and technical assistance agreements.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Manufacturing license agreements and technical... ARMS REGULATIONS AGREEMENTS, OFF-SHORE PROCUREMENT AND OTHER DEFENSE SERVICES § 124.1 Manufacturing... manufacturing license agreements, technical assistance agreements, distribution agreements, or...

  11. THE INTERNATIONAL MULTIMODAL TRANSPORT OF HAZARDOUS GOODS AND WASTE

    Directory of Open Access Journals (Sweden)

    Giancarlo Carosso

    2012-01-01

    Full Text Available The international multimodal transport of hazardous goods and waste is a sector of remarkable economic importance. This transport activity is connected to several productive sectors and it can have considerable repercussions on the environment and health as well as on the safety of the workers and third parties that study in the same field. A certain part of the transport of hazardous goods and waste is managed by organized criminals who can obtain enormous savings by neglecting the measures necessary to protect the environment and safety. The legitimate economy is thus damaged and, above all, the efforts the International Community has made since the fifties-sixties, concerning the regulation of the complex aspects of this activity, are undermined. Two distinct judicial models exist at an international level concerning hazardous waste and goods: “transboundary movement” and “international transport”. The purpose of these models is to regulate a phenomenon which, although very complex and articulated, requires a homogeneous view. The international multimodal transport judicial model is here examined in 3 subsequent stages: (1 the general aspects and the details along the entire chain, starting from the loading operations, then going on to the transport itself and ending up with the unloading at its final destination; (2 the controls on the respect of international legislation on this topic; (3 a study case is conducted pertaining to the extensive PCB category which, from a judicial point of view, in certain cases can be considered hazardous goods and in other cases hazardous waste. The aim of the study is to supply decision makers with indications that can be used to improve the efficacy and the effectiveness of the regulations at a UN level and of the cascading particular agreements for the various means of transport. The international multimodal transport judicial model suffers from the uncertainties that were already

  12. When good statistical models of aquifer heterogeneity go right: The impact of aquifer permeability structures on 3D flow and transport

    Science.gov (United States)

    Jankovic, I.; Maghrebi, M.; Fiori, A.; Dagan, G.

    2017-02-01

    Natural gradient steady flow of mean velocity U takes place in heterogeneous aquifers of random logconductivity Y = lnK , characterized by the univariate PDF f(Y) and autocorrelation ρY. Solute transport is analyzed through the Breakthrough Curve (BTC) at planes at distance x from the injection plane. The study examines the impact of permeability structures sharing same f(Y) and ρY, but differing in higher order statistics (integral scales of variograms of Y classes) upon the numerical solution of flow and transport. Flow and transport are solved for 3D structures, rather than the 2D models adopted in most of previous works. We considered a few permeability structures, including the widely employed multi-Gaussian, the connected and disconnected fields introduced by Zinn and Harvey [2003] and a model characterized by equipartition of the correlation scale among Y values. We also consider the impact of statistical anisotropy of Y, the shape of ρY and local diffusion. The main finding is that unlike 2D, the prediction of the BTC of ergodic plumes by numerical and analytical models for different structures is quite robust, displaying a seemingly universal behavior, and can be used with confidence in applications. However, as a prerequisite the basic parameters KG (the geometric mean), σY2 (the logconductivity variance) and I (the horizontal integral scale of ρY) have to be identified from field data. The results suggest that narrowing down the gap between the BTCs in applications can be achieved by obtaining Kef (the effective conductivity) or U independently (e.g. by pumping tests), rather than attempting to characterize the permeability structure beyond f(Y) and ρY.

  13. 77 FR 58140 - Notice of Agreements Filed

    Science.gov (United States)

    2012-09-19

    .... Title: U.S. Supplemental Agreement to HLC Agreement. Parties: BBC Chartering & Logistics GmbH & Co. KG; Beluga Chartering GmbH; Chipolbrok; Clipper Project Ltd.; Hyndai Merchant Marine Co., Ltd.; Industrial...

  14. 77 FR 56209 - Notice of Agreements Filed

    Science.gov (United States)

    2012-09-12

    .... Title: U.S. Supplemental Agreement to HLC Agreement. Parties: BBC Chartering & Logistics GmbH & Co. KG; Beluga Chartering GmbH; Chipolbrok; Clipper Project Ltd.; Hyndai Merchant Marine Co., Ltd.; Industrial...

  15. 75 FR 37805 - Notice of Agreements Filed

    Science.gov (United States)

    2010-06-30

    ....gov . Agreement No.: 012032-005. Title: CMA CGM/MSC/Maersk Line North and Central China-US Pacific Coast Two-Loop Space Charter, Sailing and Cooperative Working Agreement. Parties: A.P. Moller-Maersk...

  16. 78 FR 57390 - Notice of Agreements Filed

    Science.gov (United States)

    2013-09-18

    ...; Washington, DC 20006-4007. Synopsis: The amendment deletes A.P. Moller Maersk A/S trading under the name of Maersk Line as a party to the agreement. Agreement No.: 201157-003. Title: USMX-ILA Master...

  17. 76 FR 12962 - Notice of Agreements Filed

    Science.gov (United States)

    2011-03-09

    ... trade. Agreement No.: 012032-007. Title: CMA CGM/MSC/Maersk Line North and Central China-US Pacific Coast Two-Loop Space Charter, Sailing and Cooperative Working Agreement. Parties: A.P. Moller-Maersk...

  18. 76 FR 72408 - Notice of Agreements Filed

    Science.gov (United States)

    2011-11-23

    ....S. East coast. Agreement No.: 012146. Title: HLAG/HSDG USWC-Mediterranean Vessel Sharing Agreement..., Morocco, Panama, Colombia, the Dominican Republic, Canada, and Mexico. By Order of the Federal...

  19. Evolutionary biology studies on the Iris pumila clonal plant: Advantages of a good model system, main findings and directions for further research

    Directory of Open Access Journals (Sweden)

    Tarasjev A.

    2012-01-01

    Full Text Available Evolutionary studies on the dwarf bearded iris, Iris pumila L., a perennial clonal monocot with hermaphroditic enthomophylous flowers, have been conducted during the last three decades on plants and populations from the Deliblato Sands in Serbia. In this review we discuss the main advantages of this model system that have enabled various studies of several important genetic, ecological, and evolutionary issues at different levels of biological organization (molecular, physiological, anatomical, morphological and population. Based on published research and its resonance in international scientific literature, we present the main findings obtained from these studies, and discuss possible directions for further research.

  20. TRIPs Agreement, Important Multilateral WTO Treaty

    Directory of Open Access Journals (Sweden)

    Oana-Maria Florescu

    2006-08-01

    Full Text Available This article aims at presenting the content and the frame of the TRIPs. Agreement. It starts by introducing the reader to the terms that defined the world economical climate by the time of the Agreement negociation. Also, it explains the need of having an Agreement on intellectual property rights with impact on the business world. Moreover, the article reviews the main provisions of the Agreement and the most important intellectual property rights.

  1. Parent and Teacher Agreement in the Assessment of Pervasive Developmental Disorders.

    Science.gov (United States)

    Szatmari, P.; And Others

    1994-01-01

    Parents and teachers of 83 young children diagnosed with a pervasive developmental disorder rated each child on the Autism Behavior Checklist (ABC) and the Vineland Adaptive Behavior Scales (VABS). Although there was good agreement between informants on the VABS, there was virtually no agreement on the ABC, with parents reporting more autistic and…

  2. 7 CFR 900.109 - Mediation agreement.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Mediation agreement. 900.109 Section 900.109 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... Mediation agreement. An agreement arrived at by mediation shall not become effective until approved by...

  3. 77 FR 58592 - Modified Norway Post Agreement

    Science.gov (United States)

    2012-09-21

    ... Modified Norway Post Agreement AGENCY: Postal Regulatory Commission. ACTION: Notice. SUMMARY: The Commission is noticing a recently-filed Postal Service request to include a modified Norway Post Agreement... existing bilateral agreement for inbound competitive services with Posten Norge AS (Modified Norway...

  4. 7 CFR 966.111 - Marketing Agreement.

    Science.gov (United States)

    2010-01-01

    ... and Regulations Definitions § 966.111 Marketing Agreement. Marketing Agreement means Marketing... 7 Agriculture 8 2010-01-01 2010-01-01 false Marketing Agreement. 966.111 Section 966.111 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE...

  5. 7 CFR 946.101 - Marketing agreement.

    Science.gov (United States)

    2010-01-01

    ... WASHINGTON Rules and Regulations Definitions § 946.101 Marketing agreement. Marketing agreement means... 7 Agriculture 8 2010-01-01 2010-01-01 false Marketing agreement. 946.101 Section 946.101 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE...

  6. 7 CFR 917.101 - Marketing agreement.

    Science.gov (United States)

    2010-01-01

    ... CALIFORNIA Rules and Regulations Definitions § 917.101 Marketing agreement. Marketing agreement means... 7 Agriculture 8 2010-01-01 2010-01-01 false Marketing agreement. 917.101 Section 917.101 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE...

  7. 77 FR 38288 - Notice of Agreement Filed

    Science.gov (United States)

    2012-06-27

    ... . Agreement No.: 012177. Title: MSC/Maersk Line U.S.-Panama Space Charter Agreement. Parties: Mediterranean Shipping Company S.A. and A.P. Moller-Maersk A/S, trading under the name Maersk Line. Filing Party: Wayne R... agreement authorizes MSC to charter space to Maersk Line in the trade between ports in Panama and ports...

  8. 75 FR 3466 - Notice of Agreement Filed

    Science.gov (United States)

    2010-01-21

    ... . Agreement No.: 012048-001. Title: The Container Trades Statistics Agreement. Parties: A.P. Moeller-Maersk A/S; China Shipping Container Lines Co., Ltd.; COSCO Container Lines Company Ltd.; CMA CGM S.A.; Compania Sudamericana de Vapores S.A.; Evergreen Line Joint Service Agreement; Hamburg Sud KG;...

  9. 76 FR 22104 - Notice of Agreements Filed

    Science.gov (United States)

    2011-04-20

    .... Title: Hamburg Sud/Maersk Line Vessel Sharing Agreement. Parties: Hamburg-Sud and A.P. Moeller-Maersk A... 20006. Synopsis: The amendment would revise the amount of capacity provided by Maersk Line and revise... Agreement. Parties: A.P. Moller-Maersk A/S and Evergreen Line Joint Service Agreement. Filing Parties:...

  10. 76 FR 66304 - Notice of Agreements Filed

    Science.gov (United States)

    2011-10-26

    ....gov . Agreement No.: 012032-008. Title: CMA CGM/MSC/Maersk Line North and Central China-U.S. Pacific Coast Two-Loop Space Charter, Sailing and Cooperative Working Agreement. Parties: A.P. Moller-Maersk A/S... further slot exchange between Maersk Line and MSC with corresponding changes in the Agreement and...

  11. 75 FR 71704 - Notice of Agreements Filed

    Science.gov (United States)

    2010-11-24

    ....gov . Agreement No.: 012032-006. Title: CMA CGM/MSC/Maersk Line North and Central China-US Pacific Coast Two-Loop Space Charter, Sailing and Cooperative Working Agreement. Parties: A.P. Moller-Maersk A/S...: The World Liner Data Agreement. Parties: ANL Container Line Pty Ltd.; A.P. Moller-Maersk A/S; CMA...

  12. 76 FR 28778 - Notice of Agreements Filed

    Science.gov (United States)

    2011-05-18

    ... the parties' U.S. East Coast services from the agreement. Agreement No.: 012126. Title: Maersk Line...: The agreement authorizes Maersk Line to charter space to Dole in the trades between the U.S. Gulf...-Maersk A/S; CMA CGM S.A.; Hamburg-Sud; and Hapag-Lloyd AG. Filing Party: Wayne R. Rohde, Esq.; Cozen...

  13. 76 FR 44914 - Notice of Agreement Filed

    Science.gov (United States)

    2011-07-27

    ... at (202)-523-5793 or tradeanalysis@fmc.gov . Agreement No.: 012134. Title: Maersk Line/MSC Panama Space Charter Agreement. Parties: A.P. Moller-Maersk A/S and Mediterranean Shipping Company S.A. Filing.... Synopsis: The agreement authorizes MSC to charter space to Maersk Line in the trade from Panama to...

  14. 78 FR 55697 - Notice of Agreements Filed

    Science.gov (United States)

    2013-09-11

    ...; Hyundai Merchant Marine (America), Inc.; ``K'' Line America; Maersk Agency USA, Inc.; Mediterranean... Amendment removes Maersk as a party to the Agreement. Agreement No.: 012223. Title: Assessment Agreement of Carrier Members of United States Maritime Alliance, Ltd. Parties: APL, Ltd.; Atlantic Container...

  15. 78 FR 21364 - Notice of Agreements Filed

    Science.gov (United States)

    2013-04-10

    ....gov . Agreement No.: 012057-009. Title: CMA CGM/Maersk Line Space Charter, Sailing and Cooperative Working Agreement Asia to USEC and PNW-Suez/PNW & Panama Loops. Parties: A.P. Moller-Maersk A/S and CMA.... Parties: Evergreen Line Joint Service Agreement; Hanjin Shipping Co., Ltd; Nippon Yusen Kaisha; and...

  16. 47 CFR 27.602 - Lease agreements.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false Lease agreements. 27.602 Section 27.602... Lease agreements. Guard Band licensees may enter into spectrum leasing arrangements under part 1... following conditions: (a) The spectrum lease agreement between the licensee and the spectrum lessee...

  17. Private Financing of Public Goods by Means of 'Eco-Goods' Schemes

    DEFF Research Database (Denmark)

    Ueda, Yoshifumi; Wegener, Andreas; Svendsen, Gert Tinggaard

    2010-01-01

    With a view to applying to the problem of collective action for the global commons, we analyze a three-stage game model where public goods are provided by the costly leadership of a social entrepreneur for undertaking 'eco-goods' scheme. We derive (i) the conclusion that the social entrepreneur can...

  18. International trade agreements: a threat to tobacco control policy.

    Science.gov (United States)

    Shaffer, E R; Brenner, J E; Houston, T P

    2005-08-01

    International covenants establish a role for governments in ensuring the conditions for human health and wellbeing, which has been recognised as a central human right. International trade agreements, conversely, prioritize the rights of corporations over health and human rights. International trade agreements are threatening existing tobacco control policies and restrict the possibility of implementing new controls. This situation is unrecognised by many tobacco control advocates in signatory nations, especially those in developing countries. Recent agreements on eliminating various trade restrictions, including those on tobacco, have expanded far beyond simply international movement of goods to include internal tobacco distribution regulations and intellectual property rules regulating advertising and labelling. Our analysis shows that to the extent trade agreements protect the tobacco industry, in itself a deadly enterprise, they erode human rights principles and contribute to ill health. The tobacco industry has used trade policy to undermine effective barriers to tobacco importation. Trade negotiations provide an unwarranted opportunity for the tobacco industry to assert its interests without public scrutiny. Trade agreements provide the industry with additional tools to obstruct control policies in both developed and developing countries and at every level. The health community should become involved in reversing these trends, and help promote additional measures to protect public health.

  19. New strategies to ensure good patient–physician communication when treating adolescents and young adults with cancer: the proposed model of the Milan Youth Project

    Directory of Open Access Journals (Sweden)

    Magni MC

    2015-08-01

    Full Text Available Maria Chiara Magni,1 Laura Veneroni,1 Carlo Alfredo Clerici,2 Tullio Proserpio,3 Giovanna Sironi,1 Michela Casanova,1 Stefano Chiaravalli,1 Maura Massimino,1 Andrea Ferrari1 1Pediatric Oncology Unit, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy; 2Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy; 3Pastoral Care Unit, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy Abstract: Adolescence is a particularly complex time of life, entailing physiological, psychological, and social changes that further the individual's cognitive, emotional, and social growth. Being diagnosed with cancer at this time can have important consequences on an individual's emotional and physical development, and adolescent and young adult cancer patients have particular medical and psychosocial needs. Patient–physician communications are important in any clinical relationship, but fundamental in the oncological sphere because their quality can affect the patient–physician relationship, the therapeutic alliance, and patient compliance. A major challenge when dealing with adolescent and young adult patients lies in striking the right balance between their need and right to understand their disease, treatment, and prognosis, and the need for them to remain hopeful and to protect their emotional sensitivity. We herein describe the activities of the Youth Project of the Istituto Nazionale Tumori in Milan, Italy in order to share a possible model of interaction with these special patients and the tactics our group has identified to help them communicate and share their thoughts. This model implies not only the involvement of a multidisciplinary team, including psychologists and spirituality experts, but also the constitution of dedicated creative activities to give patients the opportunity to express feelings they would otherwise never feel at ease putting into words. These efforts seek the goal to minimize the potentially

  20. China-ASEAN investment agreement negotiations

    Institute of Scientific and Technical Information of China (English)

    CHEN Huiping

    2006-01-01

    China and the ASEAN are negotiating to establish a free trade area and an investment agreement is an integral part of it.The ongoing investment agreement negotiations have achieved some basic consensus as to specific contents of the agreement.However,due to the procedural obstacles and substantive controversies,the negotiations have become stagnant.In order to reach a final and successful conclusion of the investment agreement,the procedural obstacles should be' overcome and the substantive controversies be settled since the agreement has economic and political implications for both China and the ASEAN.

  1. Understanding the development of international environmental agreements

    DEFF Research Database (Denmark)

    Stærdahl, Jens

    of departure for developing the model is the actor-structure debate within social science and theory of international relations. Based on critical realism, a framework is developed specifying the relation between collective action problem situations and negotiation situations. It is argued that the main...... for practitioners and planners manoeuvring in a complex world. On the basis of a review of selected theories of international and environmental regulation, this article initiates the development of a conceptual framework for understanding the development of internationalenvironmental agreements. The point......There are many different theoretical schools concerned with how international regimes develop, and each supplies its own interpretation focusing on one or a few aspects of the process. Such ‘one shot’ explanations may be fruitful for scientific debate, but less useful as conceptual frameworks...

  2. Good Governance: The Storybook Children

    OpenAIRE

    Prijono Tjiptoherijanto

    2012-01-01

    Good governance is an important issue over the last two decades. The concept of 'good governance' has some of the following effective dimension, wich are among all, nemely : public accountability and transparencey, the role of law, anti-corruption measures, civil society participation in development, and overall respect to human right. Therefore, in the implementation, a good governance concept sholud involves the active cooperation of three elements, wich are : government, civil society, and...

  3. Negotiating Whose Property It Is, for the Public Good

    Science.gov (United States)

    Rhoades, Gary

    2017-01-01

    This chapter analyzes collective bargaining agreements in 4-year institutions of higher education, examining language surrounding ownership, use, and distribution of the proceeds of intellectual property in distance education, and identifying ways in which the public good can be, and occasionally is, built in to contractual provisions.

  4. Interactions between Drosophila and its natural yeast symbionts—Is Saccharomyces cerevisiae a good model for studying the fly-yeast relationship?

    Directory of Open Access Journals (Sweden)

    Don Hoang

    2015-08-01

    preference of D. melanogaster when given the choice between a naturally associated yeast and S. cerevisiae. We do not find a correlation between preferred yeasts and those that persist in the intestine. Notably, in no instances is S. cerevisiae preferred over the naturally associated strains. Overall, our results show that D. melanogaster-yeast interactions are more complex than might be revealed in experiments that use only S. cerevisiae. We propose that future research utilize other yeasts, and especially those that are naturally associated with Drosophila, to more fully understand the role of yeasts in Drosophila biology. Since the genetic basis of host–microbe interactions is shared across taxa and since many of these genes are initially discovered in D. melanogaster, a more realistic fly-yeast model system will benefit our understanding of host–microbe interactions throughout the animal kingdom.

  5. The Goodness of Simultaneous Fits in ISIS

    CERN Document Server

    Kühnel, Matthias; Grossberger, Christoph; Ballhausen, Ralf; Dauser, Thomas; Schwarm, Fritz-Walter; Kreykenbohm, Ingo; Nowak, Michael A; Pottschmidt, Katja; Ferrigno, Carlo; Rothschild, Richard E; Martínez-Núñez, Silvia; Torrejón, José Miguel; Fürst, Felix; Klochkov, Dmitry; Staubert, Rüdiger; Kretschmar, Peter; Wilms, Jörn

    2016-01-01

    In a previous work, we introduced a tool for analyzing multiple datasets simultaneously, which has been implemented into ISIS. This tool was used to fit many spectra of X-ray binaries. However, the large number of degrees of freedom and individual datasets raise an issue about a good measure for a simultaneous fit quality. We present three ways to check the goodness of these fits: we investigate the goodness of each fit in all datasets, we define a combined goodness exploiting the logical structure of a simultaneous fit, and we stack the fit residuals of all datasets to detect weak features. These tools are applied to all RXTE-spectra from GRO 1008-57, revealing calibration features that are not detected significantly in any single spectrum. Stacking the residuals from the best-fit model for the Vela X-1 and XTE J1859+083 data evidences fluorescent emission lines that would have gone undetected otherwise.

  6. THE GOODNESS OF SIMULTANEOUS FITS IN ISIS

    Directory of Open Access Journals (Sweden)

    Matthias Kühnel

    2016-02-01

    Full Text Available In a previous work, we introduced a tool for analyzing multiple datasets simultaneously, which has been implemented into ISIS. This tool was used to fit many spectra of X-ray binaries. However, the large number of degrees of freedom and individual datasets raise an issue about a good measure for a simultaneous fit quality. We present three ways to check the goodness of these fits: we investigate the goodness of each fit in all datasets, we define a combined goodness exploiting the logical structure of a simultaneous fit, and we stack the fit residuals of all datasets to detect weak features. These tools are applied to all RXTE-spectra from GRO 1008−57, revealing calibration features that are not detected significantly in any single spectrum. Stacking the residuals from the best-fit model for the Vela X-1 and XTE J1859+083 data evidences fluorescent emission lines that would have gone undetected otherwise.

  7. Public Goods Games on Adaptive Coevolutionary Networks

    CERN Document Server

    Shapiro, Avi M

    2016-01-01

    Productive societies feature high levels of cooperation and strong connections between individuals. Public Goods Games (PGGs) are frequently used to study the development of social connections and cooperative behavior in model societies. In such games, contributions to the public good are made only by cooperators, while all players, including defectors, can reap public goods benefits. Classic results of game theory show that mutual defection, as opposed to cooperation, is the Nash Equilibrium of PGGs in well-mixed populations, where each player interacts with all others. In this paper, we explore the coevolutionary dynamics of a low information public goods game on a network without spatial constraints in which players adapt to their environment in order to increase individual payoffs. Players adapt by changing their strategies, either to cooperate or to defect, and by altering their social connections. We find that even if players do not know other players' strategies and connectivity, cooperation can arise ...

  8. Applicant guide for the demands of expedition and agreement approval of the parcel or radioactive matter models for civil use transported on the public highway; Guide du requerant pour les demandes d'approbation d'expedition et d'agrement des modeles de colis ou de matieres radioactives a usage civil transportes sur la voie publique

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-03-15

    This guide applies to the models of parcels or radioactive materials for which an approval of the competent authorities is required by the regulations of the dangerous goods transportations. It is about models used for: radioactive materials under special shape, lowly dispersible radioactive materials, packages containing 0.1 kg or more of uranium hexafluoride, any package containing fissile materials, the B(U) type packages, and the B(M) type packages; the C type packages. (N.C.)

  9. Ecological public goods games: cooperation and bifurcation.

    Science.gov (United States)

    Hauert, Christoph; Wakano, Joe Yuichiro; Doebeli, Michael

    2008-03-01

    The Public Goods Game is one of the most popular models for studying the origin and maintenance of cooperation. In its simplest form, this evolutionary game has two regimes: defection goes to fixation if the multiplication factor r is smaller than the interaction group size N, whereas cooperation goes to fixation if the multiplication factor r is larger than the interaction group size N. Hauert et al. [Hauert, C., Holmes, M., Doebeli, M., 2006a. Evolutionary games and population dynamics: Maintenance of cooperation in public goods games. Proc. R. Soc. Lond. B 273, 2565-2570] have introduced the Ecological Public Goods Game by viewing the payoffs from the evolutionary game as birth rates in a population dynamic model. This results in a feedback between ecological and evolutionary dynamics: if defectors are prevalent, birth rates are low and population densities decline, which leads to smaller interaction groups for the Public Goods game, and hence to dominance of cooperators, with a concomitant increase in birth rates and population densities. This feedback can lead to stable co-existence between cooperators and defectors. Here we provide a detailed analysis of the dynamics of the Ecological Public Goods Game, showing that the model exhibits various types of bifurcations, including supercritical Hopf bifurcations, which result in stable limit cycles, and hence in oscillatory co-existence of cooperators and defectors. These results show that including population dynamics in evolutionary games can have important consequences for the evolutionary dynamics of cooperation.

  10. Enjoyment and the Good Life.

    Science.gov (United States)

    Estes, Cheryl; Henderson, Karla

    2003-01-01

    Presents information to update parks and recreation professionals about what recent research says in regard to enjoyment and the good life, noting what applications this research has for practitioners. The article focuses on: the good life and leisure services; happiness, subjective well-being, and intrinsic motivation; leisure, happiness, and…

  11. Good research guide, second edition

    CSIR Research Space (South Africa)

    Scholes, RJ

    2003-01-01

    Full Text Available stream_source_info Good Research Guide second ed. RJ Scholes (editor) 2003.pdf.txt stream_content_type text/plain stream_size 22 Content-Encoding ISO-8859-1 stream_name Good Research Guide second ed. RJ Scholes (editor) 2003.pdf....txt Content-Type text/plain; charset=ISO-8859-1 ...

  12. Is Good Fit Related to Good Behaviour? Goodness of Fit between Daycare Teacher-Child Relationships, Temperament, and Prosocial Behaviour

    Science.gov (United States)

    Hipson, Will E.; Séguin, Daniel G.

    2016-01-01

    The Goodness-of-Fit model [Thomas, A., & Chess, S. (1977). Temperament and development. New York: Brunner/Mazel] proposes that a child's temperament interacts with the environment to influence child outcomes. In the past, researchers have shown how the association between the quality of the teacher-child relationship in daycare and child…

  13. Is Good Fit Related to Good Behaviour? Goodness of Fit between Daycare Teacher-Child Relationships, Temperament, and Prosocial Behaviour

    Science.gov (United States)

    Hipson, Will E.; Séguin, Daniel G.

    2016-01-01

    The Goodness-of-Fit model [Thomas, A., & Chess, S. (1977). Temperament and development. New York: Brunner/Mazel] proposes that a child's temperament interacts with the environment to influence child outcomes. In the past, researchers have shown how the association between the quality of the teacher-child relationship in daycare and child…

  14. 22 CFR 124.6 - Termination of manufacturing license agreements and technical assistance agreements.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Termination of manufacturing license agreements... Termination of manufacturing license agreements and technical assistance agreements. The U.S. party to a manufacturing license or a technical assistance agreement must inform the Directorate of Defense Trade...

  15. Paying for international environmental public goods.

    Science.gov (United States)

    Arriagada, Rodrigo; Perrings, Charles

    2011-11-01

    Supply of international environmental public goods must meet certain conditions to be socially efficient, and several reasons explain why they are currently undersupplied. Diagnosis of the public goods failure associated with particular ecosystem services is critical to the development of the appropriate international response. There are two categories of international environmental public goods that are most likely to be undersupplied. One has an additive supply technology and the other has a weakest link supply technology. The degree to which the collective response should be targeted depends on the importance of supply from any one country. In principle, the solution for the undersupply lies in payments designed to compensate local providers for the additional costs they incur in meeting global demand. Targeted support may take the form of direct investment in supply (the Global Environment Facility model) or of payments for the benefits of supply (the Payments for Ecosystem Services model).

  16. Agreement between Gonioscopic Examination and Swept Source Fourier Domain Anterior Segment Optical Coherence Tomography Imaging

    Directory of Open Access Journals (Sweden)

    Mohammed Rigi

    2016-01-01

    Full Text Available Purpose. To evaluate interobserver, intervisit, and interinstrument agreements for gonioscopy and Fourier domain anterior segment optical coherence tomography (FD ASOCT for classifying open and narrow angle eyes. Methods. Eighty-six eyes with open or narrow anterior chamber angles were included. The superior angle was classified open or narrow by 2 of 5 glaucoma specialists using gonioscopy and imaged by FD ASOCT in the dark. The superior angle of each FD ASOCT image was graded as open or narrow by 2 masked readers. The same procedures were repeated within 6 months. Kappas for interobserver and intervisit agreements for each instrument and interinstrument agreements were calculated. Results. The mean age was 50.9 (±18.4 years. Interobserver agreements were moderate to good for both gonioscopy (0.57 and 0.69 and FD ASOCT (0.58 and 0.75. Intervisit agreements were moderate to excellent for both gonioscopy (0.53 to 0.86 and FD ASOCT (0.57 and 0.85. Interinstrument agreements were fair to good (0.34 to 0.63, with FD ASOCT classifying more angles as narrow than gonioscopy. Conclusions. Both gonioscopy and FD ASOCT examiners were internally consistent with similar interobserver and intervisit agreements for angle classification. Agreement between instruments was fair to good, with FD ASOCT classifying more angles as narrow than gonioscopy.

  17. A Comparative Analysis of Trade Facilitation in Selected Regional and Bilateral Trade Agreement

    OpenAIRE

    Institute for International Trade

    2006-01-01

    This study compared the treatment of trade facilitation in four selected regional trade agreements, AFTA, APEC, SAFRA and PACER, and in one bilateral free trade agreement being the Australia-Singapore Free Trade Agreement (ASFTA), with a view to determining model trade facilitation principles and measures which may be instructive for developing country negotiations and policy makers.

  18. A Comparative Analysis of Trade Facilitation in Selected Regional and Bilateral Trade Agreement

    OpenAIRE

    Wille, P.; J. Redden

    2006-01-01

    This study compares the treatment of trade facilitation in four selected regional trade agreements, AFTA, APEC, SAFTA and PACER, and in one bilateral free trade agreement being the Australia-Singapore Free Trade Agreement (ASFTA), with a view to determining model trade facilitation principles and measures which may be instructive for developing country negotiators and policy makers.

  19. Does good documentation equate to good nursing care?

    Science.gov (United States)

    Bosek, Marcia Sue DeWolf; Ring, Marcia Ellen

    2010-01-01

    Good documentation does not necessarily equate to good care. This article explores the potential underpinnings of poor documentation from an ethical decision-making lens. Nursing standards of care related to documentation are reviewed. The internal and external constraints of moral distress are considered, as is moral residue. Finally, the roles of the nurse administrator as well as specific remedial and restorative measures are suggested.

  20. Good news for young families

    CERN Multimedia

    2007-01-01

    CERN and the commune of Meyrin have just signed an agreement under which the equivalent of 20 full-time places will be reserved for the children of CERN personnel in a new crèche being built in Meyrin.

  1. Choreography Synthesis as Contract Agreement

    Directory of Open Access Journals (Sweden)

    Julien Lange

    2013-10-01

    Full Text Available We propose a formal model for distributed systems, where each participant advertises its requirements and obligations as behavioural contracts, and where multiparty sessions are started when a set of contracts allows to synthesise a choreography. Our framework is based on the CO2 calculus for contract-oriented computing, and borrows concepts and results from the session type literature. It supports sessions where the number of participants is not determined beforehand, and keeps CO2's ability to rule out participants that are culpable if contracts are not fulfilled at runtime. We show that we have progress and session fidelity in CO2, as a result of the honesty of participants — i.e., their ability to always adhere to their contracts.

  2. Spatial dilemmas of diffusible public goods.

    Science.gov (United States)

    Allen, Benjamin; Gore, Jeff; Nowak, Martin A

    2013-12-17

    The emergence of cooperation is a central question in evolutionary biology. Microorganisms often cooperate by producing a chemical resource (a public good) that benefits other cells. The sharing of public goods depends on their diffusion through space. Previous theory suggests that spatial structure can promote evolution of cooperation, but the diffusion of public goods introduces new phenomena that must be modeled explicitly. We develop an approach where colony geometry and public good diffusion are described by graphs. We find that the success of cooperation depends on a simple relation between the benefits and costs of the public good, the amount retained by a producer, and the average amount retained by each of the producer's neighbors. These quantities are derived as analytic functions of the graph topology and diffusion rate. In general, cooperation is favored for small diffusion rates, low colony dimensionality, and small rates of decay of the public good. DOI: http://dx.doi.org/10.7554/eLife.01169.001.

  3. Analysis of a cultural consensus model of two good-life sub-domains--health & well-being and migration & socioeconomic milieu--in three population groups in Croatia.

    Science.gov (United States)

    Peternel, Lana; Malnar, Ana; Klarić, Irena Martinović

    2015-07-01

    In this study the construct of a 'good life' was explored among upper secondary school senior pupils and their parents and teachers by applying cultural consensus model analysis. A total of 469 students, 474 parents and 158 teachers from four Croatian cities participated in the study, which was conducted in 2011/2012. The information collected through interviewing and free-listing during the first phase of the study was used to create a set of structured questionnaire questions as a part of the survey in the second phase of data collection. The results are reported on two good-life sub-domains: 'health & well-being' and 'migration & socioeconomic milieu'. The results indicate heterogeneity of the sample groups, incomplete inter-generational transmission of cultural values and examples of two sub-groups that resist cultural norms and do not comply with the dominant 'competence-as-sharing' paradigm. The value of testing the cultural consensus model based on the emic approach and locally significant phenomena is demonstrated for planning and conducting holistic anthropological research.

  4. Durability Choice Model of Durable Goods with Easy-to-Wear Accessories%存在易耗部件的耐用品的耐用度选择模型

    Institute of Scientific and Technical Information of China (English)

    苏昊; 谭德庆; 王艳

    2013-01-01

    Assuming a monopolist manufactures durable goods and easy-to-wear accessories (EWAs) of the durable product simultaneously. In order to study the monopolist's pricing and durability choice strategy, we build a two-period model. Through the model we find that Swan's market independence result cannot be extended to durable goods sellers. We also obtain the results about the mutual impact between the optimal durability of durable products and the durability of EWAs.%假设耐用品垄断厂商同时生产耐用品及其易耗部件两种产品,为了研究在存在易耗部件情况下,耐用品垄断厂商的销售定价和耐用度选择策略,建立了耐用品和易耗部件的需求-价格两期模型,通过模型可以发现,Swan的市场独立化的结论对于生产易耗部件的耐用品销售厂商不再成立.并且得到了在耐用品的销售市场中,耐用品垄断厂商所选择的耐用品的最优耐用度与易耗部件的耐用度之间互相影响的相关结论.

  5. AN IMPROVED AUTHENTICATED KEY AGREEMENT PROTOCOL

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    In 1999, Seo and Sweeney proposed a simple authenticated key agreement protocol that was designed to act as a Diffie-Hellman key agreement protocol with user authentication.Various attacks on this protocol are described and enhanced in the literature. Recently, Ku and Wang proposed an improved authenticated key agreement protocol, where they asserted the protocol could withstand the existing attacks. This paper shows that Ku and Wang's protocol is still vulnerable to the modification attack and presents an improved authenticated key agreement protocol to enhance the security of Ku and Wang's protocol. The protocol has more efficient performance by replacing exponentiation operations with message authentication code operations.

  6. Finite Lattice Hamiltonian Computations in the P-Representation the Schwinger Model

    CERN Document Server

    Aroca, J M; Alvarez-Campot, G; Alvarez-Campot, Gonzalo

    1999-01-01

    The Schwinger model is studied in a finite lattice by means of the P-representation. The vacuum energy, mass gap and chiral condensate are evaluated showing good agreement with the expected values in the continuum limit.

  7. Finite Lattice Hamiltonian Computations in the P-Representation: the Schwinger Model

    OpenAIRE

    1997-01-01

    The Schwinger model is studied in a finite lattice by means of the P-representation. The vacuum energy, mass gap and chiral condensate are evaluated showing good agreement with the expected values in the continuum limit.

  8. On the Superdistribution of Digital Goods

    CERN Document Server

    Schmidt, Andreas U

    2008-01-01

    Business models involving buyers of digital goods in the distribution process are called superdistribution schemes. We review the state-of-the art of research and application of superdistribution and propose systematic approach to market mechanisms using super-distribution and technical system architectures supporting it. The limiting conditions on such markets are of economic, legal, technical, and psychological nature.

  9. Spherical polymer brushes under good solvent conditions

    DEFF Research Database (Denmark)

    Lo Verso, Federica; Egorov, Sergei A.; Milchev, Andrey

    2010-01-01

    A coarse grained model for flexible polymers end-grafted to repulsive spherical nanoparticles is studied for various chain lengths and grafting densities under good solvent conditions by molecular dynamics methods and density functional theory. With increasing chain length, the monomer density...

  10. Country Size and Public Good Provision

    NARCIS (Netherlands)

    K. Staal (Klaas)

    2004-01-01

    textabstractThis paper studies the equilibrium size of countries. Individuals in small countries have greater influence over the nature of political decision mak- ing while individuals in large countries have the advantage of more public goods and lower tax rates. The model implies that (i) there ex

  11. Good Towers of Function Fields

    DEFF Research Database (Denmark)

    Bassa, Alp; Beelen, Peter; Nguyen, Nhut

    2014-01-01

    In this paper, we will give an overview of known and new techniques on how one can obtain explicit equations for candidates of good towers of function fields. The techniques are founded in modular theory (both the classical modular theory and the Drinfeld modular theory). In the classical modular...... setup, optimal towers can be obtained, while in the Drinfeld modular setup, good towers over any non-prime field may be found. We illustrate the theory with several examples, thus explaining some known towers as well as giving new examples of good explicitly defined towers of function fields....

  12. On the goodness of life

    Institute of Scientific and Technical Information of China (English)

    卿恒健

    2016-01-01

    What is life? Different people may have different opinions. For me, life is more than life and it is that brings the goodness of life. And the goodness of life lies in itself. This paper will study the goodness of life from four aspects. It nurtures from the moments. It benefits me from the moment when I have great expectations for the future, when I have huge thankfulness for my parents, when I have appreciation on the friends and teachers, and when I have great longings for the freedom.

  13. The trade effects of endogenous preferential trade agreements

    OpenAIRE

    Egger, Peter; Larch, Mario; Staub, Kevin E; Winkelmann, Rainer

    2010-01-01

    Recent work by Anderson and van Wincoop (2003) establishes an empirical modelling strategy which takes full account of the structural, non-(log-)linear impact of trade barriers on trade in new trade theory models. Structural new trade theory models have never been used to evaluate and quantify the role of endogenous preferential trade agreement (PTA) membership for trade in a way which is consistent with general equilibrium. Apart from this gap, the present paper aims at delivering an empiric...

  14. Good practices in de 'spotlight'

    NARCIS (Netherlands)

    Leendertse, P.; Wijnands, F.G.

    2010-01-01

    Vanuit de projecten ‘Duurzaam telen, begint bij jou’ en ‘Telen met Toekomst’ is gezamenlijk een keuze gemaakt om per sector vijf Good Practices extra onder de aandacht te brengen. Per sector aandacht voor gewasbescherming en teeltsystemen.

  15. Good Governance, Welfare, and Transformation

    Directory of Open Access Journals (Sweden)

    Hans-Jürgen Wagener

    2004-06-01

    Full Text Available Market conforming institutions are a precondition for a thriving and stable economy. This is the upshot of the Washington consensus or, of somewhat earlier origin, the “Eucken hypothesis”. Another hypothesis of Eucken has it that market conforming institutions are the product of a strong state. However, more general and more important than the strong state is good governance. In this paper I refer to it as the “Lorenzetti hypothesis”. The paper tries to figure out the mechanisms by which good governance and economic order influence economic outcome. Then the two hypotheses are tested for two aspects of economic outcome: productivity as measured by GNP per capita over a wide range of countries and transformation success as measured by GNP growth over the European transformation countries. The tests confirm the theoretical expectation that good governance is more important than good order

  16. THE PROBLEM OF COMMON GOOD

    Directory of Open Access Journals (Sweden)

    Witold Landowski

    2013-12-01

    Full Text Available The main purpose of this article is to discuss the relation between the understanding of human being and the concept of common good. On the one hand, materialist and spiritualist concepts of man lead to the univocal understanding of bonum commune, on the other hand, dualist anthropology entails a breakdown of the unity of common good. The author reveals weak points of these approaches and undertakes an attempt of examining realist vision of man and its impact on the notion of bonum commune. He starts with analyzing the complex structure of human being, which includes the potential and actual nature of human person. Against the background of the personalist anthropology, the author concludes that the common good has not only a material or instrumental, but above all a personal dimension, which makes this good both common and non-antagonistic. [The article written in Polish

  17. The Messiness of Common Good

    DEFF Research Database (Denmark)

    Feldt, Liv Egholm

    that a distinction between the non-civil and the civil is more fruitful, if we want to understand the past, present and future messiness in place in defining the common good. Based on an ethnographic case analysis of a Danish corporate foundation between 1920 and 2014 the paper shows how philanthropic gift...... has been messed up with other logics and that it is this mess that creates contemporary definitions of the common good....

  18. Good Conduct in the Sciences

    DEFF Research Database (Denmark)

    Hansen, Vagn Lundsgaard

    2006-01-01

    What is scientific dishonesty? How to handle the problem? How to prevent it? These three questions are discussed in an international perspective, focusing on ways of achieving and maintaining good conduct in the sciences.......What is scientific dishonesty? How to handle the problem? How to prevent it? These three questions are discussed in an international perspective, focusing on ways of achieving and maintaining good conduct in the sciences....

  19. Depreciation of public goods in spatial public goods games

    Science.gov (United States)

    Shi, Dong-Mei; Zhuang, Yong; Li, Yu-Jian; Wang, Bing-Hong

    2011-10-01

    In real situations, the value of public goods will be reduced or even lost because of external factors or for intrinsic reasons. In this work, we investigate the evolution of cooperation by considering the effect of depreciation of public goods in spatial public goods games on a square lattice. It is assumed that each individual gains full advantage if the number of the cooperators nc within a group centered on that individual equals or exceeds the critical mass (CM). Otherwise, there is depreciation of the public goods, which is realized by rescaling the multiplication factor r to (nc/CM)r. It is shown that the emergence of cooperation is remarkably promoted for CM > 1 even at small values of r, and a global cooperative level is achieved at an intermediate value of CM = 4 at a small r. We further study the effect of depreciation of public goods on different topologies of a regular lattice, and find that the system always reaches global cooperation at a moderate value of CM = G - 1 regardless of whether or not there exist overlapping triangle structures on the regular lattice, where G is the group size of the associated regular lattice.

  20. Good covers are algorithmically unrecognizable

    CERN Document Server

    Tancer, Martin

    2012-01-01

    A good cover in R^d is a collection of open contractible sets in R^d such that the intersection of any subcollection is either contractible or empty. Motivated by an analogy with convex sets, intersection patterns of good covers were studied intensively. Our main result is that intersection patterns of good covers are algorithmically unrecognizable. More precisely, the intersection pattern of a good cover can be stored in a simplicial complex called nerve which records which subfamilies of the good cover intersect. A simplicial complex is topologically d-representable if it is isomorphic to the nerve of a good cover in R^d. We prove that it is algorithmically undecidable whether a given simplicial complex is topologically d-representable for any fixed d \\geq 5. As an auxiliary result we prove that if a simplicial complex is PL embeddable into R^d, then it is topologically d-representable. We also supply this result with showing that if a "sufficiently fine" subdivision of a k-dimensional complex is d-represen...

  1. Cooperative monitoring of regional security agreements

    Energy Technology Data Exchange (ETDEWEB)

    Pregenzer, A.L.; Vannoni, M.; Biringer, K.L. [Sandia National Labs., Albuquerque, NM (United States). Nonproliferation and Arms Control Analysis Dept.

    1996-11-01

    This paper argues that cooperative monitoring plays a critical role in the implementation of regional security agreements and confidence building measures. A framework for developing cooperative monitoring options is proposed and several possibilities for relating bilateral and regional monitoring systems to international monitoring systems are discussed. Three bilateral or regional agreements are analyzed briefly to illustrate different possibilities. These examples illustrate that the relationship of regional or bilateral arms control or security agreements to international agreements depends on a number of factors: the overlap of provisions between regional and international agreements; the degree of interest in a regional agreement among the international community; efficiency in implementing the agreement; and numerous political considerations. Given the importance of regional security to the international community, regions should be encouraged to develop their own infrastructure for implementing regional arms control and other security agreements. A regional infrastructure need not preclude participation in an international regime. On the contrary, establishing regional institutions for arms control and nonproliferation could result in more proactive participation of regional parties in developing solutions for regional and international problems, thereby strengthening existing and future international regimes. Possible first steps for strengthening regional infrastructures are identified and potential technical requirements are discussed.

  2. 7 CFR 1424.5 - Agreement process.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Agreement process. 1424.5 Section 1424.5 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOENERGY PROGRAM § 1424.5 Agreement process. (a)...

  3. 12 CFR 619.9240 - Participation agreement.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Participation agreement. 619.9240 Section 619.9240 Banks and Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM DEFINITIONS § 619.9240 Participation agreement. A contract under which a lender agrees to sell a portion of a loan to one or...

  4. Your EHR license agreement: critical issues.

    Science.gov (United States)

    Shay, Daniel F

    2014-01-01

    This article discusses several key provisions and concepts in software license agreements for electronic health records. It offers insight into what physician practices can expect to find in their license agreements, as well as practical advice on beneficial provisions. The article examines contractual language relating to term and termination, technical specifications and support, and compliance with governmental programs.

  5. Approximation algorithms for nonbinary agreement forests

    NARCIS (Netherlands)

    Iersel, L.J.J. van; Kelk, S.M.; Lekic, N.; Stougie, L.

    2012-01-01

    Given two rooted phylogenetic trees on the same set of taxa X, the Maximum Agreement Forest problem (MAF) asks to find a forest that is, in a certain sense, common to both trees and has a minimum number of components. The Maximum Acyclic Agreement Forest problem (MAAF) has the additional restriction

  6. 48 CFR 1542.1203 - Processing agreements.

    Science.gov (United States)

    2010-10-01

    ... MANAGEMENT CONTRACT ADMINISTRATION Novation and Change of Name Agreements 1542.1203 Processing agreements. (a... required documentary evidence. (2) Verify the accuracy of the list of contracts through the Contract... to the Director, Policy, Training and Oversight Division, and to each affected contract office....

  7. 76 FR 11473 - Notice of Agreements Filed

    Science.gov (United States)

    2011-03-02

    ...; American President Lines, Ltd.; Maersk Line Limited; and Zim Integrated Shipping Services, Ltd. Filing... American President Lines Ltd. and APL Co Pte. Ltd. Agreement No.: 012036-002. Title: Maersk Line/MSC TP5... revise the amount of space to be chartered. Agreement No.: 012119. Title: Maersk Line/CMA CGM TP5...

  8. 78 FR 78956 - Notice of Agreements Filed

    Science.gov (United States)

    2013-12-27

    ... . Agreement No.: 012032-009. Title: CMA CGM/MSC/Maersk Line North and Central China-US Pacific Coast Three... overall slots allocations. The amendment also adds new language authorizing Maersk Line to charter space to CMA CGM on its TP6 service. Agreement No.: 012238. Title: HLAG/Maersk Line Gulf-Central...

  9. 75 FR 67749 - Notice of Agreements Filed

    Science.gov (United States)

    2010-11-03

    ...: APL/Maersk Line Reciprocal Space Charter Agreement. Parties: American President Lines, Ltd.; APL Co....: 011435-014. Title: APL/HLAG Space Charter Agreement. Parties: American President Lines, Ltd.; APL Co. Pte.... Moller-Maersk A/S; CMA CGM S.A.; Hamburg-S d; and Hapag-Lloyd AG. Filing Party: Wayne R. Rohde,...

  10. 78 FR 66713 - Notice of Agreements Filed

    Science.gov (United States)

    2013-11-06

    ....; American President Lines, Ltd.; A.P. Moller-Maersk A/S; CMA CGM, S.A.; Atlantic Container Line; China... Caribbean Services LLC; Hybur Ltd.; King Ocean Services Limited; Seaboard Marine, Ltd.; Seafreight Line, Ltd... would add US Lines Limited as a party to the agreement. Agreement No.: 011284-072. Title: Ocean...

  11. 78 FR 40739 - Notice of Agreements Filed

    Science.gov (United States)

    2013-07-08

    ... . Agreement No.: 012084-002. Title: HLAG/Maersk Line Gulf-South America Slot Charter Agreement. Parties: A.P. Moller-Maersk A/S and Hapag-Lloyd AG. Filing Party: Robert K. Magovern, Esq.; Cozen O'Connor; 1627 I... service string from which Maersk could charter space from Hapag-Lloyd. The parties have...

  12. 78 FR 64940 - Notice of Agreements Filed

    Science.gov (United States)

    2013-10-30

    .... Agreement No.: 012230. Title: P3 Network Vessel Sharing Agreement. Parties: A.P. Moller-Maersk A/S trading under the name Maersk Line; CMA CGM S.A.; and MSC Mediterranean Shipping Company, S.A. Filing Party... Yusen Kaisha and Eukor Car Carrier Inc. ] Filing Party: Robert Shababb, Corporate Counsel, NYK...

  13. 77 FR 18815 - Notice of Agreements Filed

    Science.gov (United States)

    2012-03-28

    ... . Agreement No.: 012037-003. Title: Maersk Line/CMA CGM TA3 Space Charter Agreement. Parties: A.P. Moeller-Maersk A/S and CMA CGM S.A. Filing Party: Wayne R. Rohde, Esq.; Cozen O'Connor; 1627 I Street NW.,...

  14. 77 FR 42310 - Notice of Agreements Filed

    Science.gov (United States)

    2012-07-18

    ... . Agreement No.: 012119-001. Title: Maersk Line/CMA CGM TP5 Space Charter Agreement. Parties: A.P. Moller-Maersk A/S and CMA CGM S.A. Filing Parties: Wayne Rohde, Esq.; Cozen O'Connor; 1627 I Street NW.; Suite... language reflecting the fact that Maersk's TP5 service will be operated in cooperation with another...

  15. 77 FR 59193 - Notice of Agreement Filed

    Science.gov (United States)

    2012-09-26

    ... . Agreement No.: 012159-001. Title: Maersk Line/New World Alliance Slot Exchange Agreement. Parties: A.P. Moller-Maersk A/S trading under the name of Maersk Line; American President Lines, Ltd.; APL Co. Pte, Ltd.; Hyundai Merchant Marine Co., Ltd.; and Mitsui O.S.K. Lines, Ltd. (``MOL''). Filing Party: David F....

  16. 75 FR 69079 - Notice of Agreements Filed

    Science.gov (United States)

    2010-11-10

    ....gov . Agreement No.: 011261-009. Title: ACL/Wallenius Wilhelmsen Lines Agreement. Parties: Atlantic Container Line AB and Wallenius Wilhelmsen Logistics AS (``WWL''). Filing Party: Wayne R. Rohde, Esq.; Cozen...: A.P. Moller-Maersk A/S; CMA CGM S.A.; Compania Chilena de Navegacion Interoceanica S.A.;...

  17. 75 FR 74732 - Notice of Agreements Filed

    Science.gov (United States)

    2010-12-01

    ... APL's corporate address. Agreement No.: 012086-001. Title: Maersk Line/Horizon Lines Space Charter Agreement. Parties: A.P. Moller-Maersk A/S and Horizon Lines, LLC. Filing Party: Matthew Thomas, Esq.; Reed...-Maersk A/S; APL Co. Pte Ltd.; Compania Chilena de Navegacion Interoceanica, S.A.; Compania Sud...

  18. 76 FR 7209 - Notice of Agreements Filed

    Science.gov (United States)

    2011-02-09

    ... Lines, Ltd.; APL Co. PTE Ltd.; A.P. Moller-Maersk A/S; and Hapag-Lloyd USA, LLC. Filing Party: Wayne... Line, Ltd. as a party to the agreement. Agreement No.: 012061-002. Title: CMA CGM/Maersk Line Space....: 010982-048. Title: Florida-Bahamas Shipowners and Operators Association. Parties: Bernuth Lines,...

  19. 76 FR 41794 - Notice of Agreements Filed

    Science.gov (United States)

    2011-07-15

    ..., S.A.; Frontier Liner Services, Inc.; Hamburg-S d; Interocean Lines, Inc.; King Ocean Services..., Ltd. (dba Ecuadorian Line); and Trinity Shipping Line. Filing Party: Wayne R. Rohde, Esq.; Cozen O.... Moller-Maersk A/S as a party to the agreement. Agreement No.: 011814-005. Title: HSDG/King Ocean...

  20. 75 FR 78245 - Notice of Agreements Filed

    Science.gov (United States)

    2010-12-15

    ... Services, Inc.; Farrell Lines, Inc.; Hapag-Lloyd USA, LLC; Maersk Line, Inc.; Maersk Line, Limited; and...: Evergreen Line Joint Service Agreement and A.P. Moller- Maersk A/S. Filing Party: Paul M. Keane, Esq...: The agreement authorizes Maersk to charter space from Evergreen Line in the trade from ports in...