Sample records for models direct comparison

  1. Comparison of NGA-West2 directivity models (United States)

    Spudich, Paul A.; Rowshandel, Badie; Shahi, Shrey; Baker, Jack W.; Chiou, Brian S-J


    Five directivity models have been developed based on data from the NGA-West2 database and based on numerical simulations of large strike-slip and reverse-slip earthquakes. All models avoid the use of normalized rupture dimension, enabling them to scale up to the largest earthquakes in a physically reasonable way. Four of the five models are explicitly “narrow-band” (in which the effect of directivity is maximum at a specific period that is a function of earthquake magnitude). Several strategies for determining the zero-level for directivity have been developed. We show comparisons of maps of the directivity amplification. This comparison suggests that the predicted geographic distributions of directivity amplification are dominated by effects of the models' assumptions, and more than one model should be used for ruptures dipping less than about 65 degrees.

  2. Computational comparison of quantum-mechanical models for multistep direct reactions

    International Nuclear Information System (INIS)

    Koning, A.J.; Akkermans, J.M.


    We have carried out a computational comparison of all existing quantum-mechanical models for multistep direct (MSD) reactions. The various MSD models, including the so-called Feshbach-Kerman-Koonin, Tamura-Udagawa-Lenske and Nishioka-Yoshida-Weidenmueller models, have been implemented in a single computer system. All model calculations thus use the same set of parameters and the same numerical techniques; only one adjustable parameter is employed. The computational results have been compared with experimental energy spectra and angular distributions for several nuclear reactions, namely, 90 Zr(p,p') at 80 MeV, 209 Bi(p,p') at 62 MeV, and 93 Nb(n,n') at 25.7 MeV. In addition, the results have been compared with the Kalbach systematics and with semiclassical exciton model calculations. All quantum MSD models provide a good fit to the experimental data. In addition, they reproduce the systematics very well and are clearly better than semiclassical model calculations. We furthermore show that the calculated predictions do not differ very strongly between the various quantum MSD models, leading to the conclusion that the simplest MSD model (the Feshbach-Kerman-Koonin model) is adequate for the analysis of experimental data

  3. Initial Comparison of Direct and Legacy Modeling Approaches for Radial Core Expansion Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Shemon, Emily R. [Argonne National Lab. (ANL), Argonne, IL (United States)


    not conservative and could be overestimating reactivity feedback effects that are closely tied to reactor safety. We conclude that there is indeed value in performing direct simulation of deformed meshes despite the increased computational expense. PROTEUS-SN is already part of the SHARP multi-physics toolkit where both thermal hydraulics and structural mechanical feedback modeling can be applied but this is the first comparison of direct simulation to legacy techniques for radial core expansion.

  4. Simulation of mixture microstructures via particle packing models and their direct comparison with real mixtures (United States)

    Gulliver, Eric A.

    The objective of this thesis to identify and develop techniques providing direct comparison between simulated and real packed particle mixture microstructures containing submicron-sized particles. This entailed devising techniques for simulating powder mixtures, producing real mixtures with known powder characteristics, sectioning real mixtures, interrogating mixture cross-sections, evaluating and quantifying the mixture interrogation process and for comparing interrogation results between mixtures. A drop and roll-type particle-packing model was used to generate simulations of random mixtures. The simulated mixtures were then evaluated to establish that they were not segregated and free from gross defects. A powder processing protocol was established to provide real mixtures for direct comparison and for use in evaluating the simulation. The powder processing protocol was designed to minimize differences between measured particle size distributions and the particle size distributions in the mixture. A sectioning technique was developed that was capable of producing distortion free cross-sections of fine scale particulate mixtures. Tessellation analysis was used to interrogate mixture cross sections and statistical quality control charts were used to evaluate different types of tessellation analysis and to establish the importance of differences between simulated and real mixtures. The particle-packing program generated crescent shaped pores below large particles but realistic looking mixture microstructures otherwise. Focused ion beam milling was the only technique capable of sectioning particle compacts in a manner suitable for stereological analysis. Johnson-Mehl and Voronoi tessellation of the same cross-sections produced tessellation tiles with different the-area populations. Control charts analysis showed Johnson-Mehl tessellation measurements are superior to Voronoi tessellation measurements for detecting variations in mixture microstructure, such as altered

  5. Direct Comparison of the Precision of the New Hologic Horizon Model With the Old Discovery Model. (United States)

    Whittaker, LaTarsha G; McNamara, Elizabeth A; Vath, Savoun; Shaw, Emily; Malabanan, Alan O; Parker, Robert A; Rosen, Harold N


    Previous publications suggested that the precision of the new Hologic Horizon densitometer might be better than that of the previous Discovery model, but these observations were confounded by not using the same participants and technologists on both densitometers. We sought to study this issue methodically by measuring in vivo precision in both densitometers using the same patients and technologists. Precision studies for the Horizon and Discovery models were done by acquiring spine, hip, and forearm bone mineral density twice on 30 participants. The set of 4 scans on each participant (2 on the Discovery, 2 on the Horizon) was acquired by the same technologist using the same scanning mode. The pairs of data were used to calculate the least significant change according to the International Society for Clinical Densitometry guidelines. The significance of the difference between least significant changes was assessed using a Wilcoxon signed-rank test of the difference between the mean square error of the absolute value of the differences between paired measurements on the Discovery (Δ-Discovery) and the mean square error of the absolute value of the differences between paired measurements on the Horizon (Δ-Horizon). At virtually all anatomic sites, there was a nonsignificant trend for the precision to be better for the Horizon than for the Discovery. As more vertebrae were excluded from analysis, the precision deteriorated on both densitometers. The precision between densitometers was almost identical when reporting only 1 vertebral body. (1) There was a nonsignificant trend for greater precision on the new Hologic Horizon compared with the older Discovery model. (2) The difference in precision of the spine bone mineral density between the Horizon and the Discovery models decreases as fewer vertebrae are included. (3) These findings are substantially similar to previously published results which had not controlled as well for confounding from using different

  6. Drag Coefficient Comparisons Between Observed and Model Simulated Directional Wave Spectra Under Hurricane Conditions (United States)


    Ocean Modelling 102 (2016) 1–13 Contents lists available at ScienceDirect Ocean Modelling journal homepage: Drag ...2015 Revised 3 February 2016 Accepted 16 April 2016 Available online 19 April 2016 Keywords: Wind waves WAVEWATCH III, Drag coefficient Wave...1688 source function is used to calculate drag coefficients from both the scanning radar altimeter (SRA) measured two dimensional wave spectra

  7. A comparison between skeleton and bounding box models for falling direction recognition (United States)

    Narupiyakul, Lalita; Srisrisawang, Nitikorn


    Falling is an injury that can lead to a serious medical condition in every range of the age of people. However, in the case of elderly, the risk of serious injury is much higher. Due to the fact that one way of preventing serious injury is to treat the fallen person as soon as possible, several works attempted to implement different algorithms to recognize the fall. Our work compares the performance of two models based on features extraction: (i) Body joint data (Skeleton Data) which are the joint's positions in 3 axes and (ii) Bounding box (Box-size Data) covering all body joints. Machine learning algorithms that were chosen are Decision Tree (DT), Naïve Bayes (NB), K-nearest neighbors (KNN), Linear discriminant analysis (LDA), Voting Classification (VC), and Gradient boosting (GB). The results illustrate that the models trained with Skeleton data are performed far better than those trained with Box-size data (with an average accuracy of 94-81% and 80-75%, respectively). KNN shows the best performance in both Body joint model and Bounding box model. In conclusion, KNN with Body joint model performs the best among the others.

  8. A directional Secular Variation Curve for Greece for the last 4500 years: Comparison with regional and global geomagnetic field models (United States)

    de Marco, E.; Tema, E.; Lanos, P.; Kondopoulou, D.


    A total of 64 Greek archaeomagnetic directional data have been used for the establishment of the variation of the Earth’s magnetic field in Greece over the past 4500 years. Most of the data come from archaeological material but some data from Santorini lava flows are also included. The data ages range from Minoan times (~2500 BC) up to the last century with a gap around 10th to 6th century BC. All data have been relocated to Athens (37.97° N, 23.72° E) using the virtual geomagnetic pole method. Data coming from direct measurements available in Greece for the last four centuries have been also added. The secular variation (SV) curves for declination and inclination have been obtained using hierarchical Bayesian modelling. For comparison, the dataset has been also analysed using the bi-variate moving average window technique with 150 years time window shifted by 75 years. The obtained smoothed curves accompanied by a 95 % confidence envelope are compared with archaeomagnetic data from Mediterranean area and with SV curves from nearby countries. The Greek curves have also been compared with the predictions of the SCHA.DIF.3K regional and the CALS7K and ARCH3K global geomagnetic field models. Despite the differences recognised between these models, the Greek archaeomagnetic SV curve is in reasonably good agreement with their basic trends. The proposed directional SV curve can contribute, together with the intensity SV curve previously published for Greece, to the reliable archaeomagnetic dating of Greek artefacts based on the full description of the Earth’s magnetic field (declination, inclination, intensity). It is clear that the continuous update of the dataset with new results from well-dated archaeological material will increase the precision of the SV curve, especially for the time periods poorly covered by data.

  9. Comparison of Two Methods of Obtaining Digital Orthodontic Models: Direct vs. Indirect (United States)


    evaluated by comparing digital measurements of both tooth size, overbite , and overjet to those made on the original plaster models. Statistically...significant differences were found for tooth size and overbite but were considered clinically irrelevant. With the recent increase in the interest

  10. A modeled comparison of direct and food web-mediated impacts of common pesticides on Pacific salmon.

    Directory of Open Access Journals (Sweden)

    Kate H Macneale

    Full Text Available In the western United States, pesticides used in agricultural and urban areas are often detected in streams and rivers that support threatened and endangered Pacific salmon. Although concentrations are rarely high enough to cause direct salmon mortality, they can reach levels sufficient to impair juvenile feeding behavior and limit macroinvertebrate prey abundance. This raises the possibility of direct adverse effects on juvenile salmon health in tandem with indirect effects on salmon growth as a consequence of reduced prey abundance. We modeled the growth of ocean-type Chinook salmon (Oncorhynchus tshawytscha at the individual and population scales, investigating insecticides that differ in how long they impair salmon feeding behavior and in how toxic they are to salmon compared to macroinvertebrates. The relative importance of these direct vs. indirect effects depends both on how quickly salmon can recover and on the relative toxicity of an insecticide to salmon and their prey. Model simulations indicate that when exposed to a long-acting organophosphate insecticide that is highly toxic to salmon and invertebrates (e.g., chlorpyrifos, the long-lasting effect on salmon feeding behavior drives the reduction in salmon population growth with reductions in prey abundance having little additional impact. When exposed to short-acting carbamate insecticides at concentrations that salmon recover from quickly but are lethal to invertebrates (e.g., carbaryl, the impacts on salmon populations are due primarily to reductions in their prey. For pesticides like carbaryl, prey sensitivity and how quickly the prey community can recover are particularly important in determining the magnitude of impact on their predators. In considering both indirect and direct effects, we develop a better understanding of potential impacts of a chemical stressor on an endangered species and identify data gaps (e.g., prey recovery rates that contribute uncertainty to these

  11. The dimensional nature of eating pathology: Evidence from a direct comparison of categorical, dimensional, and hybrid models. (United States)

    Luo, Xiaochen; Donnellan, M Brent; Burt, S Alexandra; Klump, Kelly L


    Eating disorders are conceptualized as categorical rather than dimensional in the current major diagnostic system (Diagnostic and Statistical Manual of Mental Disorders; 5th ed.; American Psychiatric Association, 2013) and in many previous studies. However, previous research has not critically evaluated this assumption or tested hybrid models (e.g., modeling latent variables with both dimensional and categorical features). Accordingly, the current study directly compared categorical, dimensional, and hybrid models for eating pathology in a large, population-based sample. Participants included 3,032 female and male twins (ages 9-30 years) from the Michigan State University Twin Registry. The Minnesota Eating Behaviors Survey was used to assess disordered eating symptoms including body dissatisfaction, weight preoccupation, binge eating, and compensatory behaviors. Results showed that dimensional models best fit the data in the overall sample as well as across subgroups divided by sex and pubertal status (e.g., prepubertal vs. postpubertal). It is interesting to note that the results favored more categorical models when using a case-control subset of our sample with participants who either endorsed substantial eating pathology or no/little eating pathology. Overall, findings provide support for a dimensional conceptualization of eating pathology and underscore the importance of using community samples to capture the full range of severity of eating pathology when investigating questions about taxonomy. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  12. Direct Aerosol Radiative Forcing from Combined A-Train Observations - Preliminary Comparisons with AeroCom Models and Pathways to Observationally Based All-sky Estimates (United States)

    Redemann, J.; Livingston, J. M.; Shinozuka, Y.; Kacenelenbogen, M. S.; Russell, P. B.; LeBlanc, S. E.; Vaughan, M.; Ferrare, R. A.; Hostetler, C. A.; Rogers, R. R.; Burton, S. P.; Torres, O.; Remer, L. A.; Stier, P.; Schutgens, N.


    We describe a technique for combining CALIOP aerosol backscatter, MODIS spectral AOD (aerosol optical depth), and OMI AAOD (absorption aerosol optical depth) retrievals for the purpose of estimating full spectral sets of aerosol radiative properties, and ultimately for calculating the 3-D distribution of direct aerosol radiative forcing. We present results using one year of data collected in 2007 and show comparisons of the aerosol radiative property estimates to collocated AERONET retrievals. Use of the recently released MODIS Collection 6 data for aerosol optical depths derived with the dark target and deep blue algorithms has extended the coverage of the multi-sensor estimates towards higher latitudes. Initial calculations of seasonal clear-sky aerosol radiative forcing based on our multi-sensor aerosol retrievals compare well with over-ocean and top of the atmosphere IPCC-2007 model-based results, and with more recent assessments in the "Climate Change Science Program Report: Atmospheric Aerosol Properties and Climate Impacts" (2009). For the first time, we present comparisons of our multi-sensor aerosol direct radiative forcing estimates to values derived from a subset of models that participated in the latest AeroCom initiative. We discuss the major challenges that exist in extending our clear-sky results to all-sky conditions. On the basis of comparisons to suborbital measurements, we present some of the limitations of the MODIS and CALIOP retrievals in the presence of adjacent or underlying clouds. Strategies for meeting these challenges are discussed.

  13. Comparison of the radioiodinated serum albumin (RISA) dilution technique with direct volumetric measurements in animal models of peritoneal dialysis. (United States)

    Van Biesen, Wim; De Vriese, An S; Carlsson, Ola; Van Landschoot, Mike; Dheuvaert, Tomy; Lameire, Norbert H; Devriese, An S


    Rat models of peritoneal dialysis (PD) are useful for studying the physiology of peritoneal transport and evaluating new osmotic agents. Intraperitoneal (IP) solute concentrations and their evolution over time are easy to measure, but IP volume (IPV) is not. Direct volumetric measurements are the "gold standard:" but they are expensive and do not allow for repetitive measurements in the same animal. The Indicator dilution technique is therefore used as an alternative. However, that technique is based on assumptions that are not always valid. The present study compares direct volume measurement with the Indicator dilution technique [radioiodinated serum albumin (RISA)] to determine the IPV over time curves In a rat model of PD. In series 1, 17 Sprague-Dawley rats were instilled IP with 25 mL 1.36% glucose dialysate through a Teflon catheter. In 9 animals, 0.35 mL dialysate was sampled and discarded at time points 0, 3,15, 30, 60, 180, and 240 minutes. In the other 8 animals, no sampling was performed. At 240 minutes, all 12 animals were humanely killed, and direct volumetric measurements of IPV were performed. In series 2, rats were instilled IP with 25 mL 1.36% glucose dialysate containing 18.5 kBq 1311 RISA. In 9 animals, dialysate was sampled at 0, 3, 15, 30, 60, 90, 120,180, and 240 minutes for the construction of the RISA concentration-over-time curve, and to calculate the elimination constant Ke. At 30, 60, 180, and 240 minutes, dialysate was sampled in 6 different animals (total n = 24) to calculate IPV using the RISA dilution technique. Immediately afterward, the animals were humanely killed, and direct volumetric measurements of IPV were performed. In series 1, after 240 minutes' dwell time, the IPV was lower in the sampled animals as compared with the non sampled animals (27.11 +/- 1.85 mL vs 30.75 +/- 0.59 mL, p = 0.001). In series 2, the evolution of RISA activity in the dialysate over time was described by piecewise linear regression, yielding 3

  14. Determining Sound Source Orientation from Source Directivity and Real Multi-Microphone Recordings: Experimental Comparisons using both Analytical and Measured Directivity Models

    DEFF Research Database (Denmark)

    Guarato, Francesco; Hallam, John; Vanderelst, Dieter


    This paper presents a method for estimating the orientation of a directional sound source emitting a broadband acoustic signal being recorded by a microphone array, given source directivity, microphone positions with respect to the source and recordings of the call. Such a method has been tested ....... The signal emitted by the source is broadband, like the signals many bats use while echolocating. Indeed, our intended final application of the method is to estimate the orientations a bat assumes while hunting over water....

  15. Parallel direct numerical simulation of turbulent flows in rotor-stator cavities. Comparison with k-{epsilon} modeling; Simulation numerique directe parallele d`ecoulements turbulents en cavites rotor-stator comparaisons avec les modilisations k-{epsilon}

    Energy Technology Data Exchange (ETDEWEB)

    Jacques, R.; Le Quere, P.; Daube, O. [Centre National de la Recherche Scientifique (CNRS), 91 - Orsay (France)


    Turbulent flows between a fixed disc and a rotating disc are encountered in various applications like turbo-machineries or torque converters of automatic gear boxes. These flows are characterised by particular physical phenomena mainly due to the effects of rotation (Coriolis and inertia forces) and thus, classical k-{epsilon}-type modeling gives approximative results. The aim of this work is to study these flows using direct numerical simulation in order to provide precise information about the statistical turbulent quantities and to improve the k-{epsilon} modeling in the industrial MATHILDA code of the ONERA and used by SNECMA company (aerospace industry). The results presented are restricted to the comparison between results obtained with direct simulation and results obtained with the MATHILDA code in the same configuration. (J.S.) 8 refs.

  16. [18F]DPA-714: Direct comparison with [11C]PK11195 in a model of cerebral ischemia in rats

    International Nuclear Information System (INIS)

    Boutin, Herve; Prenant, Christian; Smigova, Alison; Cawthorne, Christopher; Brown, Gavin; Herholz, Karl; Maroy, Renaud; Galea, James; Greenhalgh, Andrew D.; Rothwell, Nancy J.; Julyan, Peter; Wilkinson, Shane M.; Banister, Samuel D.; Kassiou, Michael


    Neuro-inflammation is involved in several brain disorders and can be monitored through expression of the translocator protein 18 kDa (TSPO) on activated micro-glia. In recent years, several new PET radioligands for TSPO have been evaluated in disease models. [ 18 F]DPA-714 is a TSPO radiotracer with great promise; however results vary between different experimental models of neuro-inflammation. To further examine the potential of [ 18 F]DPA-714, it was compared directly to [ 11 C]PK11195 in experimental cerebral ischaemia in rats. Under anaesthesia, the middle cerebral artery of adult rats was occluded for 60 min using the filament model. Rats were allowed recovery for 5 to 7 days before one hour dynamic PET scans with [ 11 C]PK11195 and/or [ 18 F]DPA-714 under anaesthesia. Uptake of [ 11 C]PK11195 vs [ 18 F]DPA-714 in the ischemic lesion was similar (core/contralateral ratio: 2.8460.67 vs 2.2860.34 respectively), but severity of the brain ischemia and hence ligand uptake in the lesion appeared to vary greatly between animals scanned with [ 11 C]PK11195 or with [ 18 F]DPA-714. To solve this issue of inter-individual variability, we performed a direct comparison of [ 11 C]PK11195 and [ 18 F]DPA-714 by scanning the same animals sequentially with both tracers within 24 h. In this direct comparison, the core/contralateral ratio (3.3561.21 vs 4.6662.50 for [ 11 C]PK11195 vs [ 18 F]DPA-714 respectively) showed a significantly better signal-to-noise ratio (1.6 (1.3-1.9, 95%CI) fold by linear regression) for [ 18 F]DPA-714. In a clinically relevant model of neuro-inflammation, uptake for both radiotracers appeared to be similar at first, but a high variability was observed in our model. Therefore, to truly compare tracers in such models, we performed scans with both tracers in the same animals. By doing so, our result demonstrated that [ 18 F]DPA-714 displayed a higher signal-to-noise ratio than [ 11 C]PK11195. Our results suggest that, with the longer half-life of [ 18 F

  17. CCF model comparison

    International Nuclear Information System (INIS)

    Pulkkinen, U.


    The report describes a simple comparison of two CCF-models, the ECLM, and the Beta-model. The objective of the comparison is to identify differences in the results of the models by applying the models in some simple test data cases. The comparison focuses mainly on theoretical aspects of the above mentioned CCF-models. The properties of the model parameter estimates in the data cases is also discussed. The practical aspects in using and estimating CCFmodels in real PSA context (e.g. the data interpretation, properties of computer tools, the model documentation) are not discussed in the report. Similarly, the qualitative CCF-analyses needed in using the models are not discussed in the report. (au)

  18. A Comparison of Expedition Medical Condition List Treatment Directives with Integrated Medical Model Simulation Data Presentation and Briefing Report (United States)

    Lewis, Robert


    This aerospace medicine clerkship project is under the direction of Dr. Sharmila Watkins and is in cooperation with Dr. Eric Kerstman and Dr. Ronak Shah. The questions of the research project are: 1. What are the main drivers of evacuation and loss of crew life (LOCL) on three Design Reference Missions (DRMs): Near Earth Asteroid (NEA), Lunar Sortie and Lunar Outpost using an inexhaustible International Space Station medical kit 2. What are the treatment designations for these driving medical conditions as listed in Expedition Medical Condition List (EMCL) 3. Do the drivers make sense in the context of the given Design Reference Mission (DRM) 4. Do any EMCL treatment designations need re-assessing.

  19. A Direct Comparison between Norepinephrine and Phenylephrine for Augmenting Spinal Cord Perfusion in a Porcine Model of Spinal Cord Injury. (United States)

    Streijger, Femke; So, Kitty; Manouchehri, Neda; Gheorghe, Ana; Okon, Elena B; Chan, Ryan M; Ng, Benjamin; Shortt, Katelyn; Sekhon, Mypinder S; Griesdale, Donald E; Kwon, Brian K


    Current clinical guidelines recommend elevating the mean arterial blood pressure (MAP) to increase spinal cord perfusion in patients with acute spinal cord injury (SCI). This is typically achieved with vasopressors such as norepinephrine (NE) and phenylephrine (PE). These drugs differ in their pharmacological properties and potentially have different effects on spinal cord blood flow (SCBF), oxygenation (PO 2 ), and downstream metabolism after injury. Using a porcine model of thoracic SCI, we evaluated how these vasopressors influenced intraparenchymal SCBF, PO 2 , hydrostatic pressure, and metabolism within the spinal cord adjacent to the injury site. Yorkshire pigs underwent a contusion/compression SCI at T10 and were randomized to receive either NE or PE for MAP elevation of 20 mm Hg, or no MAP augmentation. Prior to injury, a combined SCBF/PO 2 sensor, a pressure sensor, and a microdialysis probe were inserted into the spinal cord adjacent to T10 at two locations: a "proximal" site and a "distal" site, 2 mm and 22 mm from the SCI, respectively. At the proximal site, NE and PE resulted in little improvement in SCBF during cord compression. Following decompression, NE resulted in increased SCBF and PO 2 , whereas decreased levels were observed for PE. However, both NE and PE were associated with a gradual decrease in the lactate to pyruvate (L/P) ratio after decompression. PE was associated with greater hemorrhage through the injury site than that in control animals. Combined, our results suggest that NE promotes better restoration of blood flow and oxygenation than PE in the traumatically injured spinal cord, thus providing a physiological rationale for selecting NE over PE in the hemodynamic management of acute SCI.

  20. Bony ingrowth potential of 3D printed porous titanium alloy: a direct comparison of interbody cage materials in an in vivo ovine lumbar fusion model. (United States)

    McGilvray, Kirk; Easley, Jeremiah; Seim, Howard B; Regan, Daniel; Berven, Sigurd H; Hsu, Wellington K; Mroz, Thomas E; Puttlitz, Christian M


    There is significant variability in the materials commonly used for interbody cages in spine surgery. It is theorized that 3-D printed interbody cages utilizing porous titanium material can provide more consistent bone ingrowth and biological fixation. The purpose of this study was to provide an evidence-based approach to decision making regarding interbody materials for spinal fusion. Comparative animal study. A skeletally mature ovine lumbar fusion model was utilized for this study. Interbody fusions were performed at (L2-L3 and L4-L5) in 27 mature sheep using three different interbody cages (i.e., polyetheretherketone [PEEK], plasma sprayed porous titanium coated PEEK [PSP], and 3-D printed porous titanium alloy cage [PTA]). Non-destructive kinematic testing was performed in the three primary directions of motion. The specimens were then analyzed using micro-computed tomography (µCT); quantitative measures of the bony fusion were performed. Histomorphometric analyses were also performed in the sagittal plane through the interbody device. Outcome parameters were compared between cage designs and time-points. Flexion-extension range of motion (ROM) was statistically reduced for the PTA group as compared to the PEEK cages at 16 weeks (p-value = 0.02). Only the PTA cages demonstrated a statistically significant decrease in ROM and increase in stiffness across all three loading directions between the 8-week and 16-week sacrifice time-points (p-value ≤ 0.01). Micro-CT data demonstrated significantly greater total bone volume within the graft window for the PTA cages at both 8-weeks and 16-weeks compared to the PEEK cages (p-value < 0.01). A direct comparison of interbody implants demonstrates significant and measurable differences in biomechanical, µCT, and histologic performance in an ovine model. The 3-D printed porous titanium interbody cage resulted in statistically significant reductions in ROM, increases in the bone ingrowth profile, as well as average

  1. Directed Innovation of Business Models

    Directory of Open Access Journals (Sweden)

    Stelian Brad


    Full Text Available Business model innovation is an important issue to keep business competitive and increase company’s profits. Due to many market attractors, identification of appropriate paths of business model evolution is a painful and risky process. To improve decision’s effectiveness in this process, an architectural construct of analysis and conceptualization for business model innovation that combines directed evolution and blue ocean concepts is proposed in this paper under the name of directed innovation. It displays the key points where innovations would happen to direct adaptation of the business model towards sustainable competitiveness. Formulation of mature solutions is supported by inventive problem solving tools. The significance of the directed innovation approach is demonstrated in a case study dealing with business model innovation of a software company.

  2. Simple model for directed networks (United States)

    Morelli, Luis G.


    We study a model for directed networks based on the Watts-Stogatz model for small-world phenomena. We focus on some topological aspects of directed networks inspired in food web theory, namely, the fraction of basal and top nodes in the network and node level distributions. We argue that in directed networks basal nodes play an important role, collecting information or resources from the environment. We give analytical expressions for the fraction of basal and top nodes for the model, and study the node level distributions with numerical simulations.

  3. Directed Innovation of Business Models


    Stelian Brad; Emilia Brad


    Business model innovation is an important issue to keep business competitive and increase company’s profits. Due to many market attractors, identification of appropriate paths of business model evolution is a painful and risky process. To improve decision’s effectiveness in this process, an architectural construct of analysis and conceptualization for business model innovation that combines directed evolution and blue ocean concepts is proposed in this paper under the name o...

  4. A comparison of different strategies in multivariate regression models for the direct determination of Mn, Cr, and Ni in steel samples using laser-induced breakdown spectroscopy (United States)

    Luna, Aderval S.; Gonzaga, Fabiano B.; da Rocha, Werickson F. C.; Lima, Igor C. A.


    Laser-induced breakdown spectroscopy (LIBS) analysis was carried out on eleven steel samples to quantify the concentrations of chromium, nickel, and manganese. LIBS spectral data were correlated to known concentrations of the samples using different strategies in partial least squares (PLS) regression models. For the PLS analysis, one predictive model was separately generated for each element, while different approaches were used for the selection of variables (VIP: variable importance in projection and iPLS: interval partial least squares) in the PLS model to quantify the contents of the elements. The comparison of the performance of the models showed that there was no significant statistical difference using the Wilcoxon signed rank test. The elliptical joint confidence region (EJCR) did not detect systematic errors in these proposed methodologies for each metal.

  5. Meso-scale modelling of directional solidification and comparison with in situ X-ray radiographic observations made during the MASER-12 XRMON microgravity experiment

    Energy Technology Data Exchange (ETDEWEB)

    Murphy, A.G., E-mail: [School of Mechanical and Materials Engineering, University College Dublin (Ireland); Reinhart, G.; Nguyen-Thi, H.; Salloum Abou Jaoude, G. [Aix-Marseille Univ., Campus Saint-Jérome Case 142, 13397 Marseille Cedex 20 (France); CNRS, IM2NP UMR 7334, Campus Saint-Jérome Case 142, 13397 Marseille Cedex 20 (France); Browne, D.J. [School of Mechanical and Materials Engineering, University College Dublin (Ireland)


    Highlights: •Mesoscopic simulation of in situ X-ray monitored solidification in microgravity. •Extent and magnitude of undercooled zone ahead of dendrite front predicted. •Dynamic thermal response of new XRMON-GF Bridgman furnace analysed. -- Abstract: Computational modelling of advanced solidification processes has made considerable advances over the last half century, with ever increasing levels of modelling complexity. There is, therefore, an increasing need for state of the art experimental investigation to provide suitable validation for these model predictions. In situ X-ray radiography has become a powerful tool for solidification experimentation. Using either synchrotron or microfocus X-ray sources, thin samples, encased in X-ray transparent crucibles, can be directionally or isothermally solidified, allowing for direct real time observation of dynamic solidification phenomena. This paper presents the results of a meso-scale Front Tracking simulation of a directional solidification experiment, performed using an Al–20 wt.% Cu alloy, carried out under microgravity conditions on board the MASER 12 sounding rocket. The sample was mounted in a Bridgman type gradient furnace and solidified using a prescribed cooling regime with a constant gradient, thus promoting directional solidification in the field of view. The actual thermal gradient in the sample was found to be lower than the nominal thermal gradient, as set/recorded by thermocouples embedded in the heater elements. The adjusted thermal data were supplied as inputs to the Front Tracking model and good agreement was then observed between the model predictions and the in situ observations. The extent and amplitude of the undercooled zone ahead of the columnar front was predicted based on analytical growth kinetics laws and the results were also compared to analytical models of columnar-to-equiaxed transition (CET) prediction.

  6. Biomechanical comparison of expanded polytetrafluoroethylene (ePTFE) and PTFE interpositional patches and direct tendon-to-bone repair for massive rotator cuff tears in an ovine model. (United States)

    McKeown, Andrew Dj; Beattie, Rebekah F; Murrell, George Ac; Lam, Patrick H


    Massive irreparable rotator cuff tears are a difficult problem. Modalities such as irrigation and debridement, partial repair, tendon transfer and grafts have been utilized with high failure rates and mixed results. Synthetic interpositional patch repairs are a novel and increasingly used approach. The present study aimed to examine the biomechanical properties of common synthetic materials for interpositional repairs in contrast to native tendon. Six ovine tendons, six polytetrafluoroethylene (PTFE) felt sections and six expanded PTFE (ePTFE) patch sections were pulled-to-failure to analyze their biomechanical and material properties. Six direct tendon-to-bone surgical method repairs, six interpositional PTFE felt patch repairs and six interpositional ePTFE patch repairs were also constructed in ovine shoulders and pulled-to-failure to examine the biomechanical properties of each repair construct. Ovine tendon had higher load-to-failure (591 N) and had greater stiffness (108 N/mm) than either PTFE felt (296 N, 28 N/mm) or ePTFE patch sections (323 N, 34 N/mm). Both PTFE felt and ePTFE repair techniques required greater load-to-failure (225 N and 177 N, respectively) than direct tendon-to-bone surgical repairs (147 N) in ovine models. Synthetic materials lacked several biomechanical properties, including strength and stiffness, compared to ovine tendon. Interpositional surgical repair models with these materials were significantly stronger than direct tendon-to-bone model repairs.

  7. New directions in social comparison research

    NARCIS (Netherlands)

    Buunk, Abraham (Bram); Mussweiler, T


    This article notices that social comparison theory has developed from being a focused theoretical statement on the use of others for self-evaluation into a lively and varied area of research encompassing many different paradigms, approaches and applications. A recent 'renaissance' in social


    African Journals Online (AJOL)



    Mar 3, 2004 ... the borderline high LDL-C group of the National Cholesterol Education Program. (NCEP) classification (LDL-C 3.36 - 4.14mmol/L). Conclusion: There is lack of agreement between the FF and the Abbott direct LDL-. C assay. If the two methods are used interchangeably, there may be confusion in the.

  9. Comparison of the direct enzyme assay method with the membrane ...

    African Journals Online (AJOL)

    Comparison of the direct enzyme assay method with the membrane filtration technique in the quantification and monitoring of microbial indicator organisms – seasonal variations in the activities of coliforms and E. coli, temperature and pH.

  10. Design and Comparison Direct Torque Control Techniques for Induction Motors

    DEFF Research Database (Denmark)

    Blaabjerg, Frede; Kazmierkowski, Marian P.; Zelechowski, Marcin


    In this paper a comparison of two significant control methods of induction motor are presented. The first one is a classical Direct Torque and Flux Control (DTC) and is compared with a scheme, which uses Space Vector Modulator (DTC-SVM). A comparison in respect to dynamic and steady state...

  11. Direct Comparisons of Ice Cloud Microphysical Properties Simulated by the Community Atmosphere Model CAM5 with ARM SPartICus Observations (United States)

    Wu, C.; Liu, X.; Zhang, K.; Diao, M.; Gettelman, A.


    Cirrus clouds in the upper troposphere play a key role in the Earth radiation budget, and their radiative forcing depends strongly on number concentration and size distribution of ice particles. In this study we evaluate the cloud microphysical properties simulated by the Community Atmosphere Model version 5.4 (CAM5) against the Small Particles in Cirrus (SPartICus) observations over the ARM South Great Plain (SGP) site between January and June 2010. Model simulation is performed using specific dynamics to preserve prognostic meteorology (U, V, and T) close to GEOS-5 analysis. Model results collocated with SPartICus flight tracks spatially and temporally are directly compared with the observations. We compare CAM5 simulated ice crystal number concentration (Ni), ice particle size distribution, ice water content (IWC), and Ni co-variances with temperature and vertical velocity with the statistics from SPartICus observations. All analyses are restricted to T ≤ -40°C and in a 6°×6° area centered at SGP. Model sensitivity tests are performed with different ice nucleation mechanisms and with the effects of pre-existing ice crystals to reflect the uncertainties in cirrus parameterizations. In addition, different threshold size for autoconversion of cloud ice to snow (Dcs) is also tested. We find that (1) a distinctly high Ni (100-1000 L-1) often occurred in the observations but is significantly underestimated in the model, which may be due to the smaller relative humidity with respect to ice (RHi) in the simulation that could suppress the homogeneous nucleation, (2) a positive correlation exists between Ni and vertical velocity variance (σw) at horizontal scales up to 50 km in the observation, and the model can reproduce this relationship but tends to underestimate Ni when σw is relatively small, (3) simulated Ni differs greatly among the sensitive experiments, and simulated IWC is also sensitive to the cirrus parameterizations but to a lesser extent. Moreover

  12. Modeling of 2008 Kasatochi Volcanic Sulfate Direct Radiative Forcing: Assimilation of OMI SO2 Plume Height Data and Comparison with MODIS and CALIOP Observations (United States)

    Wang, J.; Park, S.; Zeng, J.; Ge, C.; Yang, K.; Carn, S.; Krotkov, N.; Omar, A. H.


    Volcanic SO2 column amount and injection height retrieved from the Ozone Monitoring Instrument (OMI) with the Extended Iterative Spectral Fitting (EISF) technique are used to initialize a global chemistry transport model (GEOS-Chem) to simulate the atmospheric transport and lifecycle of volcanic SO2 and sulfate aerosol from the 2008 Kasatochi eruption, and to subsequently estimate the direct shortwave, top-of-the-atmosphere radiative forcing of the volcanic sulfate aerosol. Analysis shows that the integrated use of OMI SO2 plume height in GEOS-Chem yields: (a) good agreement of the temporal evolution of 3-D volcanic sulfate distributions between model simulations and satellite observations from the Moderate Resolution Imaging Spectroradiometer (MODIS) and Cloud-Aerosol Lidar with Orthogonal Polarisation (CALIOP), and (b) an e-folding time for volcanic SO2 that is consistent with OMI measurements, reflecting SO2 oxidation in the upper troposphere and stratosphere is reliably represented in the model. However, a consistent (approx. 25 %) low bias is found in the GEOS-Chem simulated SO2 burden, and is likely due to a high (approx.20 %) bias of cloud liquid water amount (as compared to the MODIS cloud product) and the resultant stronger SO2 oxidation in the GEOS meteorological data during the first week after eruption when part of SO2 underwent aqueous-phase oxidation in clouds. Radiative transfer calculations show that the forcing by Kasatochi volcanic sulfate aerosol becomes negligible 6 months after the eruption, but its global average over the first month is -1.3W/sq m, with the majority of the forcing-influenced region located north of 20degN, and with daily peak values up to -2W/sq m on days 16-17. Sensitivity experiments show that every 2 km decrease of SO2 injection height in the GEOS-Chem simulations will result in a approx.25% decrease in volcanic sulfate forcing; similar sensitivity but opposite sign also holds for a 0.03 m increase of geometric radius of

  13. Comparison of Airway Responses Induced in a Mouse Model by the Gas and Particulate Fractions of Gasoline Direct Injection Engine Exhaust

    Directory of Open Access Journals (Sweden)

    Caitlin L. Maikawa


    Full Text Available Diesel exhaust has been associated with asthma, but its response to other engine emissions is not clear. The increasing prevalence of vehicles with gasoline direct injection (GDI engines motivated this study, and the objective was to evaluate pulmonary responses induced by acute exposure to GDI engine exhaust in an allergic asthma murine model. Mice were sensitized with an allergen to induce airway hyperresponsiveness or treated with saline (non-allergic group. Animals were challenged for 2-h to exhaust from a laboratory GDI engine operated at conditions equivalent to a highway cruise. Exhaust was filtered to assess responses induced by the particulate and gas fractions. Short-term exposure to particulate matter from GDI engine exhaust induced upregulation of genes related to polycyclic aromatic hydrocarbon (PAH metabolism (Cyp1b1 and inflammation (TNFα in the lungs of non-allergic mice. High molecular weight PAHs dominated the particulate fraction of the exhaust, and this response was therefore likely attributable to the presence of these PAHs. The particle fraction of GDI engine exhaust further contributed to enhanced methacholine responsiveness in the central and peripheral tissues in animals with airway hyperresponsiveness. As GDI engines gain prevalence in the vehicle fleet, understanding the health impacts of their emissions becomes increasingly important.

  14. Comparison of Airway Responses Induced in a Mouse Model by the Gas and Particulate Fractions of Gasoline Direct Injection Engine Exhaust. (United States)

    Maikawa, Caitlin L; Zimmerman, Naomi; Ramos, Manuel; Shah, Mittal; Wallace, James S; Pollitt, Krystal J Godri


    Diesel exhaust has been associated with asthma, but its response to other engine emissions is not clear. The increasing prevalence of vehicles with gasoline direct injection (GDI) engines motivated this study, and the objective was to evaluate pulmonary responses induced by acute exposure to GDI engine exhaust in an allergic asthma murine model. Mice were sensitized with an allergen to induce airway hyperresponsiveness or treated with saline (non-allergic group). Animals were challenged for 2-h to exhaust from a laboratory GDI engine operated at conditions equivalent to a highway cruise. Exhaust was filtered to assess responses induced by the particulate and gas fractions. Short-term exposure to particulate matter from GDI engine exhaust induced upregulation of genes related to polycyclic aromatic hydrocarbon (PAH) metabolism ( Cyp1b1 ) and inflammation ( TNFα ) in the lungs of non-allergic mice. High molecular weight PAHs dominated the particulate fraction of the exhaust, and this response was therefore likely attributable to the presence of these PAHs. The particle fraction of GDI engine exhaust further contributed to enhanced methacholine responsiveness in the central and peripheral tissues in animals with airway hyperresponsiveness. As GDI engines gain prevalence in the vehicle fleet, understanding the health impacts of their emissions becomes increasingly important.

  15. Directional wave measurements and modelling

    Digital Repository Service at National Institute of Oceanography (India)

    Anand, N.M.; Nayak, B.U.; Bhat, S.S.; SanilKumar, V.

    -dimensional spectra and sech@u2@@ (beta theta) spreading function seem to provide a better estimate of the directional energy distribution for the monsoon conditions. While non-linear wave-wave interaction seems to be the major governing factor in the directional...

  16. The proof of two-temperature kinetic (2 T fluid) model by means of comparison of kinetic and fluid calculations at simulation of plasma of positive column of direct-current oxygen discharge

    International Nuclear Information System (INIS)

    Bogdanov, E.A.; Kudryavtsev, A.A.; Tsendin, L.D.; Arslanbekov, R.R.; Kolobov, V.I.; Kudryavtsev, V.V.


    The comparison of the kinetic and fluid calculations by modeling the plasma of the positive column of the direct-current discharge in oxygen is carried out through the CDFRC commercial software, making it possible to conduct the simulations in the arbitrary 3D geometry with application of both the fluid equations for all the components and with the solution of the kinetic equation for determining the electrons distribution function. It is shown, that both in the local and in the nonlocal modes of the electrons distribution function formation its nonmaxwelliality is well accounted for through approximation by two groups of electrons. This makes it possible to account in the simplest way for the kinetic effects within the frames of the traditional fluid model through applying the proposed two-temperature approximation of the nonequilibrium and nonlocal electrons distribution function [ru

  17. Comparison of the Economic Factors that Influence Foreign Direct ...

    African Journals Online (AJOL)

    Comparison of the Economic Factors that Influence Foreign Direct Investment Growth in Nigeria and India. ... The PDF file you selected should load here if your Web browser has a PDF reader plug-in installed (for example, a recent version of Adobe Acrobat Reader). If you would like more information about how to print, ...

  18. A Comparison of the Effects of Direct Modeling and Video Modeling Provided by Peers to Students with Autism Who Are Attending in Rural Play Teaching in an Inclusive Setting (United States)

    Odluyurt, Serhat


    In the present research, the peers of children with autism at primary school level and in an inclusive environment were taught using direct modeling and video modeling education processes, and it was observed whether or not they could effectively and efficiently teach how to play games to their friends with autism. This study used adapted…

  19. A Computer Model for Direct Carbonate Fuel Cells

    Energy Technology Data Exchange (ETDEWEB)

    Ding, J.; Patel, P.S.; Farooque, M.; Maru, H.C.


    A 3-D computer model, describing fluid flow, heat and mass transfer, and chemical and electrochemical reaction processes, has been developed for guiding the direct carbonate fuel cell (DFC) stack design. This model is able to analyze the direct internal reforming (DIR) as well as the integrated IIR (indirect internal reforming)-DIR designs. Reasonable agreements between computed and fuel cell tested results, such as flow variations, temperature distributions, cell potentials, and exhaust gas compositions as well as methane conversions, were obtained. Details of the model and comparisons of the modeling results with experimental DFC stack data are presented in the paper.

  20. Dermal uptake directly from air under transient conditions: advances in modeling and comparisons with experimental results for human subjects

    DEFF Research Database (Denmark)

    Morrison, G C; Weschler, Charles J.; Bekö, Gabriel


    transfer of SVOCs to sinks like clothing or clean air. We test the model by simulating di-ethyl phthalate (DEP) and di-n-butyl phthalate (DnBP) exposures of six bare-skinned (Weschler et al. 2015, Environ. Health Perspect., 123, 928) and one clothed participant (Morrison et al. 2016, J. Expo. Sci. Environ...

  1. Comparison of Nordic dose models

    International Nuclear Information System (INIS)

    Thykier-Nielsen, S.


    A comparison is made between the models used in the four Nordic countries, Finland, Norway, Sweden and Denmark, for calculation of concentrations and doses from releases of radioactive material to the atmosphere. The comparison is limited to the near-zone models, i.e. the models for calculation of concentrations and doses within 50 km from the release point, and it comprises the following types of calculation: a. Concentrations of airborne material, b. External gamma doses from a plume, c. External gamma doses from radioactive material deposited on the ground. All models are based on the gaussian dispersion model (the gaussian plume model). Unit releases of specific isotopes under specific meteorological conditions are assumed. On the basis of the calculation results from the models, it is concluded that there are no essential differences. The difference between the calculation results only exceeds a factor of 3 in special cases. It thus lies within the known limits of uncertainty for the gaussian plume model. (author)

  2. Comparison Direction and Comparison Dimension among Disabled Individuals: Toward a Refined Conceptualization of Social Comparison under Stress. (United States)

    Buunk, Bram P.


    Illuminates the nature and direction of social comparison research using a sample of 168 Dutch individuals. Some of the findings revealed uncertainty and frustration related to a need for social comparison, a desire more for information than affiliation about similar others, and the influence of health problems in evaluating one's situation. (RJM)

  3. MCNPX Model/Table Comparison

    International Nuclear Information System (INIS)

    Hendricks, J.S.


    MCNPX is a Monte Carlo N-Particle radiation transport code extending the capabilities of MCNP4C. As with MCNP, MCNPX uses nuclear data tables to transport neutrons, photons, and electrons. Unlike MCNP, MCNPX also uses (1) nuclear data tables to transport protons; (2) physics models to transport 30 additional particle types (deuterons, tritons, alphas, pions, muons, etc.); and (3) physics models to transport neutrons and protons when no tabular data are available or when the data are above the energy range (20 to 150 MeV) where the data tables end. MCNPX can mix and match data tables and physics models throughout a problem. For example, MCNPX can model neutron transport in a bismuth germinate (BGO) particle detector by using data tables for bismuth and oxygen and using physics models for germanium. Also, MCNPX can model neutron transport in UO 2 , making the best use of physics models and data tables: below 20 MeV, data tables are used; above 150 MeV, physics models are used; between 20 and 150 MeV, data tables are used for oxygen and models are used for uranium. The mix-and-match capability became available with MCNPX2.5.b (November 2002). For the first time, we present here comparisons that calculate radiation transport in materials with various combinations of data charts and model physics. The physics models are poor at low energies (<150 MeV); thus, data tables should be used when available. Our comparisons demonstrate the importance of the mix-and-match capability and indicate how well physics models work in the absence of data tables

  4. Directions in Radiation Transport Modelling

    Directory of Open Access Journals (Sweden)

    P Nicholas Smith


    More exciting advances are on the horizon to increase the power of simulation tools. The advent of high performance computers is allowing bigger, higher fidelity models to be created, if the challenges of parallelization and memory management can be met. 3D whole core transport modelling is becoming possible. Uncertainty quantification is improving with large benefits to be gained from more accurate, less pessimistic estimates of uncertainty. Advanced graphical displays allow the user to assimilate and make sense of the vast amounts of data produced by modern modelling tools. Numerical solvers are being developed that use goal-based adaptivity to adjust the nodalisation of the system to provide the optimum scheme to achieve the user requested accuracy on the results, thus removing the need to perform costly convergence studies in space and angle etc. More use is being made of multi-physics methods in which radiation transport is coupled with other phenomena, such as thermal-hydraulics, structural response, fuel performance and/or chemistry in order to better understand their interplay in reactor cores.

  5. Evaluation of a "direct-comparison" approach to automatic switching in omnidirectional/directional hearing aids. (United States)

    Summers, Van; Grant, Ken W; Walden, Brian E; Cord, Mary T; Surr, Rauna K; Elhilali, Mounya


    Hearing aids today often provide both directional (DIR) and omnidirectional (OMNI) processing options with the currently active mode selected automatically by the device. The most common approach to automatic switching involves "acoustic scene analysis" where estimates of various acoustic properties of the listening environment (e.g., signal-to-noise ratio [SNR], overall sound level) are used as a basis for switching decisions. The current study was carried out to evaluate an alternative, "direct-comparison" approach to automatic switching that does not involve assumptions about how the listening environment may relate to microphone preferences. Predictions of microphone preference were based on whether DIR- or OMNI-processing of a given listening environment produced a closer match to a reference template representing the spectral and temporal modulations present in clean speech. A descriptive and correlational study. Predictions of OMNI/DIR preferences were determined based on degree of similarity between spectral and temporal modulations contained in a reference, clean-speech template, and in OMNI- and DIR-processed recordings of various listening environments. These predictions were compared with actual preference judgments (both real-world judgments and laboratory responses to the recordings). Predictions of microphone preference were based on whether DIR- or OMNI-processing of a given listening environment produced a closer match to a reference template representing clean speech. The template is the output of an auditory processing model that characterizes the spectral and temporal modulations associated with a given input signal (clean speech in this case). A modified version of the spectro-temporal modulation index (mSTMI) was used to compare the template to both DIR- and OMNI-processed versions of a given listening environment, as processed through the same auditory model. These analyses were carried out on recordings (originally collected by Walden et al

  6. Comparison of Vehicle Choice Models

    Energy Technology Data Exchange (ETDEWEB)

    Stephens, Thomas S. [Argonne National Lab. (ANL), Argonne, IL (United States); Levinson, Rebecca S. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Brooker, Aaron [National Renewable Energy Lab. (NREL), Golden, CO (United States); Liu, Changzheng [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Lin, Zhenhong [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Birky, Alicia [Energetics Incorporated, Columbia, MD (United States); Kontou, Eleftheria [National Renewable Energy Lab. (NREL), Golden, CO (United States)


    Five consumer vehicle choice models that give projections of future sales shares of light-duty vehicles were compared by running each model using the same inputs, where possible, for two scenarios. The five models compared — LVCFlex, MA3T, LAVE-Trans, ParaChoice, and ADOPT — have been used in support of the Energy Efficiency and Renewable Energy (EERE) Vehicle Technologies Office in analyses of future light-duty vehicle markets under different assumptions about future vehicle technologies and market conditions. The models give projections of sales shares by powertrain technology. Projections made using common, but not identical, inputs showed qualitative agreement, with the exception of ADOPT. ADOPT estimated somewhat lower advanced vehicle shares, mostly composed of hybrid electric vehicles. Other models projected large shares of multiple advanced vehicle powertrains. Projections of models differed in significant ways, including how different technologies penetrated cars and light trucks. Since the models are constructed differently and take different inputs, not all inputs were identical, but were the same or very similar where possible. Projections by all models were in close agreement only in the first few years. Although the projections from LVCFlex, MA3T, LAVE-Trans, and ParaChoice were in qualitative agreement, there were significant differences in sales shares given by the different models for individual powertrain types, particularly in later years (2030 and later). For example, projected sales shares of conventional spark-ignition vehicles in 2030 for a given scenario ranged from 35% to 74%. Reasons for such differences are discussed, recognizing that these models were not developed to give quantitatively accurate predictions of future sales shares, but to represent vehicles markets realistically and capture the connections between sales and important influences. Model features were also compared at a high level, and suggestions for further comparison

  7. A novel Direct Small World network model

    Directory of Open Access Journals (Sweden)

    LIN Tao


    Full Text Available There is a certain degree of redundancy and low efficiency of existing computer networks.This paper presents a novel Direct Small World network model in order to optimize networks.In this model,several nodes construct a regular network.Then,randomly choose and replot some nodes to generate Direct Small World network iteratively.There is no change in average distance and clustering coefficient.However,the network performance,such as hops,is improved.The experiments prove that compared to traditional small world network,the degree,average of degree centrality and average of closeness centrality are lower in Direct Small World network.This illustrates that the nodes in Direct Small World networks are closer than Watts-Strogatz small world network model.The Direct Small World can be used not only in the communication of the community information,but also in the research of epidemics.

  8. Target Scattering Metrics: Model-Model and Model Data comparisons (United States)


    be suitable for input to classification schemes. The investigated metrics are then applied to model-data comparisons. INTRODUCTION Metrics for...stainless steel replica of artillery shell Table 7. Targets used in the TIER simulations for the metrics study. C. Four Potential Metrics: Four...Four metrics were investigated. The metric, based on 2D cross-correlation, is typically used in classification algorithms. Model-model comparisons

  9. Direct comparison of SANS data with SEM image analysis

    CERN Document Server

    Ryukhtin, V


    Small-angle scattering functions in an infinite-slit geometry can be calculated directly from an image of a sample section through the scattering plane without particular assumptions about material isotropy. The method was tested on simulated images with the aim of assessing qualitatively the precision of direct comparisons of electron-microscopy images with double-crystal SANS data. The results for images of 1024 sup 2 pixels show that such calculations are reliable particularly in the central part of scattering curves and for objects with radii between about 5 and 100 pixels. For the large-Q region, substantial systematical errors due to boundary effects should be avoided by taking a sufficiently large image area compared to the dimensions of the scattering objects. (orig.)

  10. Computer Modeling of Direct Metal Laser Sintering (United States)

    Cross, Matthew


    A computational approach to modeling direct metal laser sintering (DMLS) additive manufacturing process is presented. The primary application of the model is for determining the temperature history of parts fabricated using DMLS to evaluate residual stresses found in finished pieces and to assess manufacturing process strategies to reduce part slumping. The model utilizes MSC SINDA as a heat transfer solver with imbedded FORTRAN computer code to direct laser motion, apply laser heating as a boundary condition, and simulate the addition of metal powder layers during part fabrication. Model results are compared to available data collected during in situ DMLS part manufacture.

  11. Chaotic inflation in models with flat directions

    International Nuclear Information System (INIS)

    Graziani, F.; Olive, K.


    We consider the chaotic inflationary scenario in models with flat directions. We find that unless the scalars along the flat directions have vacuum expectation values p or 10 14 M p 15 M p depending on the expectation values of the chaotic inflator, Ψ, one or two or more periods of inflation occur but with a resulting energy density perturbation δρ/ρ ≅ 10 -16 , far too small to be of any consequence for galaxy formation. Even with p only limited initial values of ≅ (3-200) M p result in inflation with reasonable density perturbations. Thus chaotic inflation in models with flat directions require rather special initial conditions. (orig.)

  12. Direct concurrent comparison of multiple pediatric acute asthma scoring instruments. (United States)

    Johnson, Michael D; Nkoy, Flory L; Sheng, Xiaoming; Greene, Tom; Stone, Bryan L; Garvin, Jennifer


    Appropriate delivery of Emergency Department (ED) treatment to children with acute asthma requires clinician assessment of acute asthma severity. Various clinical scoring instruments exist to standardize assessment of acute asthma severity in the ED, but their selection remains arbitrary due to few published direct comparisons of their properties. Our objective was to test the feasibility of directly comparing properties of multiple scoring instruments in a pediatric ED. Using a novel approach supported by a composite data collection form, clinicians categorized elements of five scoring instruments before and after initial treatment for 48 patients 2-18 years of age with acute asthma seen at the ED of a tertiary care pediatric hospital ED from August to December 2014. Scoring instruments were compared for inter-rater reliability between clinician types and their ability to predict hospitalization. Inter-rater reliability between clinician types was not different between instruments at any point and was lower (weighted kappa range 0.21-0.55) than values reported elsewhere. Predictive ability of most instruments for hospitalization was higher after treatment than before treatment (p < 0.05) and may vary between instruments after treatment (p = 0.054). We demonstrate the feasibility of comparing multiple clinical scoring instruments simultaneously in ED clinical practice. Scoring instruments had higher predictive ability for hospitalization after treatment than before treatment and may differ in their predictive ability after initial treatment. Definitive conclusions about the best instrument or meaningful comparison between instruments will require a study with a larger sample size.

  13. Prehistorical archaeomagnetic directions from Hungary in comparison with those from south-eastern Europe (United States)

    Márton, P.


    Since the beginning of the modern archaeomagnetic investigations in Hungary in the nineteen seventies, some directional data of various prehistorical ages have also accumulated beside a larger body of the historical results. These are presented here and compared with 1) coeval directional results which are available from south-eastern Europe, as well as 2) the predictions of geomagnetic field directions for Hungary of the global geomagnetic field model, CALS7K.2. The comparison with the south-eastern European data has lead to new archaeomagnetic dates for one of the studied archaeological features which are thought to be an improvement to the presently accepted radiometric dates.

  14. Modeling switching behaviour of direct selling customers

    Directory of Open Access Journals (Sweden)

    P Msweli-Mbanga


    Full Text Available The direct selling industry suffers a high turnover rate of salespeople, resulting in high costs of training new salespeople. Further costs are incurred when broken relationships with customers cause them to switch from one product supplier to another. This study identifies twelve factors that drive the switching behaviour of direct sales customers and examines the extent to which these factors influence switching. Exploratory factor analysis was used to assess the validity of these factors. The factors were represented in a model that posits that an interpersonal relationship between a direct sales person and a customer moderates the relationship between switching behaviour and loyalty. Structural equation modeling was used to test the proposed model. The author then discusses the empirical findings and their managerial implications, providing further avenues for research.

  15. Directional Dipole Model for Subsurface Scattering

    DEFF Research Database (Denmark)

    Frisvad, Jeppe Revall; Hachisuka, Toshiya; Kjeldsen, Thomas Kim


    Rendering translucent materials using Monte Carlo ray tracing is computationally expensive due to a large number of subsurface scattering events. Faster approaches are based on analytical models derived from diffusion theory. While such analytical models are efficient, they miss out on some...... translucency effects in the rendered result. We present an improved analytical model for subsurface scattering that captures translucency effects present in the reference solutions but remaining absent with existing models. The key difference is that our model is based on ray source diffusion, rather than...... similar to that of the standard dipole model, but we now have positive and negative ray sources with a mirrored pair of directions. Our model is as computationally efficient as existing models while it includes single scattering without relying on a separate Monte Carlo simulation, and the rendered images...

  16. A comparison between direct and indirect methods available for human bite mark analysis. (United States)

    Kouble, Roland F; Craig, Geoffrey T


    Comparison techniques used in bite mark analysis are many and varied, the choice of technique depending largely on personal preference. Until recently, no one technique has been shown to be better than the others, and very little research has been carried out to compare different methods. This study evaluates and compares the accuracy of direct comparisons between suspects' models and bite marks with indirect comparisons in the form of conventional traced overlays of suspects' models or a new method using photocopier-generated overlays. Artificial bite marks in pigskin were made using standardized sets of models and recorded as photographs and fingerprint powder lifts on tape. The bite mark photographs and fingerprint lifts were coded and randomized so that a blind comparison could be made with the models, traced overlays, and photocopier-generated overlays using a modified version of the American Board of Forensic Odontology Scoring (ABFO) System for Bite Marks. It was found that the photocopier-generated overlays were significantly more accurate at matching the correct bite mark to the correct models irrespective of whether the bite mark was recorded photographically or as a fingerprint lift. The photocopier-generated overlays were also found to be more sensitive at matching the correct bite marks to the correct models than the other two methods used. The modified ABFO scoring system was able to discriminate between a correct match and several incorrect matches by awarding a high score to the correct match.

  17. Surrogate Models for Direct Dark Matter Detection


    Cerdeno, D. G.; Cheek, A.; Reid, E.; Schulz, H.


    In this work we introduce RAPIDD, a surrogate model that speeds up the computation of the expected spectrum of dark matter particles in direct detection experiments. RAPIDD replaces the exact calculation of the dark matter differential rate (which in general involves up to three nested integrals) with a much faster parametrization in terms of ordinary polynomials of the dark matter mass and couplings, obtained in an initial training phase. In this article, we validate our surrogate model on t...

  18. Adiabatic equilibrium models for direct containment heating

    International Nuclear Information System (INIS)

    Pilch, M.; Allen, M.D.


    Probabilistic risk assessment (PRA) studies are being extended to include a wider spectrum of reactor plants than was considered in NUREG-1150. There is a need for simple direct containment heating (DCH) models that can be used for screening studies aimed at identifying potentially significant contributors to overall risk in individual nuclear power plants. This paper presents two adiabatic equilibrium models suitable for the task. The first, a single-cell model, places a true upper bound on DCH loads. This upper bound, however, often far exceeds reasonable expectations of containment loads based on CONTAIN calculations and experiment observations. In this paper, a two cell model is developed that captures the major mitigating feature of containment compartmentalization, thus providing more reasonable estimates of the containment load

  19. A Modeling Approach for Plastic-Metal Laser Direct Joining (United States)

    Lutey, Adrian H. A.; Fortunato, Alessandro; Ascari, Alessandro; Romoli, Luca


    Laser processing has been identified as a feasible approach to direct joining of metal and plastic components without the need for adhesives or mechanical fasteners. The present work sees development of a modeling approach for conduction and transmission laser direct joining of these materials based on multi-layer optical propagation theory and numerical heat flow simulation. The scope of this methodology is to predict process outcomes based on the calculated joint interface and upper surface temperatures. Three representative cases are considered for model verification, including conduction joining of PBT and aluminum alloy, transmission joining of optically transparent PET and stainless steel, and transmission joining of semi-transparent PA 66 and stainless steel. Conduction direct laser joining experiments are performed on black PBT and 6082 anticorodal aluminum alloy, achieving shear loads of over 2000 N with specimens of 2 mm thickness and 25 mm width. Comparison with simulation results shows that consistently high strength is achieved where the peak interface temperature is above the plastic degradation temperature. Comparison of transmission joining simulations and published experimental results confirms these findings and highlights the influence of plastic layer optical absorption on process feasibility.

  20. Quantummechanical multi-step direct models for nuclear data applications

    International Nuclear Information System (INIS)

    Koning, A.J.


    Various multi-step direct models have been derived and compared on a theoretical level. Subsequently, these models have been implemented in the computer code system KAPSIES, enabling a consistent comparison on the basis of the same set of nuclear parameters and same set of numerical techniques. Continuum cross sections in the energy region between 10 and several hundreds of MeV have successfully been analysed. Both angular distributions and energy spectra can be predicted in an essentially parameter-free manner. It is demonstrated that the quantum-mechanical MSD models (in particular the FKK model) give an improved prediction of pre-equilibrium angular distributions as compared to the experiment-based systematics of Kalbach. This makes KAPSIES a reliable tool for nuclear data applications in the afore-mentioned energy region. (author). 10 refs., 2 figs

  1. Direct modeling for computational fluid dynamics (United States)

    Xu, Kun


    All fluid dynamic equations are valid under their modeling scales, such as the particle mean free path and mean collision time scale of the Boltzmann equation and the hydrodynamic scale of the Navier-Stokes (NS) equations. The current computational fluid dynamics (CFD) focuses on the numerical solution of partial differential equations (PDEs), and its aim is to get the accurate solution of these governing equations. Under such a CFD practice, it is hard to develop a unified scheme that covers flow physics from kinetic to hydrodynamic scales continuously because there is no such governing equation which could make a smooth transition from the Boltzmann to the NS modeling. The study of fluid dynamics needs to go beyond the traditional numerical partial differential equations. The emerging engineering applications, such as air-vehicle design for near-space flight and flow and heat transfer in micro-devices, do require further expansion of the concept of gas dynamics to a larger domain of physical reality, rather than the traditional distinguishable governing equations. At the current stage, the non-equilibrium flow physics has not yet been well explored or clearly understood due to the lack of appropriate tools. Unfortunately, under the current numerical PDE approach, it is hard to develop such a meaningful tool due to the absence of valid PDEs. In order to construct multiscale and multiphysics simulation methods similar to the modeling process of constructing the Boltzmann or the NS governing equations, the development of a numerical algorithm should be based on the first principle of physical modeling. In this paper, instead of following the traditional numerical PDE path, we introduce direct modeling as a principle for CFD algorithm development. Since all computations are conducted in a discretized space with limited cell resolution, the flow physics to be modeled has to be done in the mesh size and time step scales. Here, the CFD is more or less a direct

  2. Beyond the standard model in many directions

    Energy Technology Data Exchange (ETDEWEB)

    Chris Quigg


    These four lectures constitute a gentle introduction to what may lie beyond the standard model of quarks and leptons interacting through SU(3){sub c} {direct_product} SU(2){sub L} {direct_product} U(1){sub Y} gauge bosons, prepared for an audience of graduate students in experimental particle physics. In the first lecture, I introduce a novel graphical representation of the particles and interactions, the double simplex, to elicit questions that motivate our interest in physics beyond the standard model, without recourse to equations and formalism. Lecture 2 is devoted to a short review of the current status of the standard model, especially the electroweak theory, which serves as the point of departure for our explorations. The third lecture is concerned with unified theories of the strong, weak, and electromagnetic interactions. In the fourth lecture, I survey some attempts to extend and complete the electroweak theory, emphasizing some of the promise and challenges of supersymmetry. A short concluding section looks forward.

  3. Direct comparison of hydraulic tortuosity and electric tortuosity based on finite element analysis

    Directory of Open Access Journals (Sweden)

    H. Saomoto


    Full Text Available Tortuosity is one of the key parameters to characterize the transport properties of porous media. There are many models for tortuosity estimation based on some definitions: geometric, hydraulic, electric, and diffusive definitions. However, relationships among those tortuosities remain unclear due to the lack of direct comparison on the same porous media. Here we focus on hydraulic and electric tortuosities and have conducted a series of finite element simulations with the Navier–Stokes equation and the equation for electric current to directly compare tortuosities. The results revealed that: (1 on average, hydraulic tortuosity is 15% greater than that of the electric one; (2 the proposed model based on the van Genuchten-type function successfully approximates both hydraulic and electric tortuosities; (3 tortuosities obtained from the porous media packed with circular particles and square particles show quantitatively similar trends.

  4. Incorporating direct marketing activity into latent attrition models

    NARCIS (Netherlands)

    Schweidel, David A.; Knox, George


    When defection is unobserved, latent attrition models provide useful insights about customer behavior and accurate forecasts of customer value. Yet extant models ignore direct marketing efforts. Response models incorporate the effects of direct marketing, but because they ignore latent attrition,

  5. Modeling mental spatial reasoning about cardinal directions. (United States)

    Schultheis, Holger; Bertel, Sven; Barkowsky, Thomas


    This article presents research into human mental spatial reasoning with orientation knowledge. In particular, we look at reasoning problems about cardinal directions that possess multiple valid solutions (i.e., are spatially underdetermined), at human preferences for some of these solutions, and at representational and procedural factors that lead to such preferences. The article presents, first, a discussion of existing, related conceptual and computational approaches; second, results of empirical research into the solution preferences that human reasoners actually have; and, third, a novel computational model that relies on a parsimonious and flexible spatio-analogical knowledge representation structure to robustly reproduce the behavior observed with human reasoners. Copyright © 2014 Cognitive Science Society, Inc.

  6. MCNPX Model/Table Comparison

    CERN Document Server

    Hendricks, J S


    MCNPX is a Monte Carlo N-Particle radiation transport code extending the capabilities of MCNP4C. As with MCNP, MCNPX uses nuclear data tables to transport neutrons, photons, and electrons. Unlike MCNP, MCNPX also uses (1) nuclear data tables to transport protons; (2) physics models to transport 30 additional particle types (deuterons, tritons, alphas, pions, muons, etc.); and (3) physics models to transport neutrons and protons when no tabular data are available or when the data are above the energy range (20 to 150 MeV) where the data tables end. MCNPX can mix and match data tables and physics models throughout a problem. For example, MCNPX can model neutron transport in a bismuth germinate (BGO) particle detector by using data tables for bismuth and oxygen and using physics models for germanium. Also, MCNPX can model neutron transport in UO sub 2 , making the best use of physics models and data tables: below 20 MeV, data tables are used; above 150 MeV, physics models are used; between 20 and 150 MeV, data t...

  7. Modelling direct tangible damages due to natural hazards (United States)

    Kreibich, H.; Bubeck, P.


    Europe has witnessed a significant increase in direct damages from natural hazards. A further damage increase is expected due to the on-going accumulation of people and economic assets in risk-prone areas and the effects of climate change, for instance, on the severity and frequency of drought events in the Mediterranean basin. In order to mitigate the impact of natural hazards an improved risk management based on reliable risk analysis is needed. Particularly, there is still much research effort needed to improve the modelling of damage due to natural hazards. In comparison with hazard modelling, simple approaches still dominate damage assessments, mainly due to limitations in available data and knowledge on damaging processes and influencing factors. Within the EU-project ConHaz, methods as well as data sources and terminology for damage assessments were compiled, systemized and analysed. Similarities and differences between the approaches concerning floods, alpine hazards, coastal hazards and droughts were identified. Approaches for significant improvements of direct tangible damage modelling with a particular focus on cross-hazard-learning will be presented. Examples from different hazards and countries will be given how to improve damage data bases, the understanding of damaging processes, damage models and how to conduct improvements via validations and uncertainty analyses.

  8. Comparison of Vehicle Choice Models

    Energy Technology Data Exchange (ETDEWEB)

    Stephens, Thomas S. [Argonne National Lab. (ANL), Argonne, IL (United States); Levinson, Rebecca S. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Brooker, Aaron [National Renewable Energy Lab. (NREL), Golden, CO (United States); Liu, Changzheng [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Lin, Zhenhong [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Birky, Alicia [Energetics Incorporated, Columbia, MD (United States); Kontou, Eleftheria [National Renewable Energy Lab. (NREL), Golden, CO (United States)


    Five consumer vehicle choice models that give projections of future sales shares of light-duty vehicles were compared by running each model using the same inputs, where possible, for two scenarios. The five models compared — LVCFlex, MA3T, LAVE-Trans, ParaChoice, and ADOPT — have been used in support of the Energy Efficiency and Renewable Energy (EERE) Vehicle Technologies Office in analyses of future light-duty vehicle markets under different assumptions about future vehicle technologies and market conditions. The models give projections of sales shares by powertrain technology. Projections made using common, but not identical, inputs showed qualitative agreement, with the exception of ADOPT. ADOPT estimated somewhat lower advanced vehicle shares, mostly composed of hybrid electric vehicles. Other models projected large shares of multiple advanced vehicle powertrains. Projections of models differed in significant ways, including how different technologies penetrated cars and light trucks. Since the models are constructed differently and take different inputs, not all inputs were identical, but were the same or very similar where possible.

  9. Comparison of haemoglobin estimates using direct & indirect cyanmethaemoglobin methods

    Directory of Open Access Journals (Sweden)

    Priyanka Gupta Bansal


    Interpretation & conclusions: The present findings revealed that indirect cyanmethaemoglobin method overestimated the prevalence of anaemia as compared to the direct method. However, if a correction factor is applied, indirect method could be successfully used for estimating true haemoglobin level. More studies should be undertaken to establish agreement and correction factor between direct and indirect cyanmethaemoglobin methods.

  10. The INTRACOIN model comparison project

    International Nuclear Information System (INIS)

    Lawson, G.


    The International Nuclide Transport Code Intercomparison (INTRACOIN) project is investigating the different models and associated computer codes describing the transport of radionuclides in flowing ground-water following the disposal of solid radioactive wastes in geologic formations. Level I of the project has shown good agreement in the numerical accuracy of most of the codes. In Level II the ability of the codes to model field experiments with radioactive tracers will be compared. Level III will show to what extent the adoption of different models and computer codes for the transport of radionuclides with ground water affects the results of repository assessments. (U.K.)

  11. Comparison of dark energy models after Planck 2015

    Energy Technology Data Exchange (ETDEWEB)

    Xu, Yue-Yao [Northeastern University, Department of Physics, College of Sciences, Shenyang (China); Zhang, Xin [Northeastern University, Department of Physics, College of Sciences, Shenyang (China); Peking University, Center for High Energy Physics, Beijing (China)


    We make a comparison for ten typical, popular dark energy models according to their capabilities of fitting the current observational data. The observational data we use in this work include the JLA sample of type Ia supernovae observation, the Planck 2015 distance priors of cosmic microwave background observation, the baryon acoustic oscillations measurements, and the direct measurement of the Hubble constant. Since the models have different numbers of parameters, in order to make a fair comparison, we employ the Akaike and Bayesian information criteria to assess the worth of the models. The analysis results show that, according to the capability of explaining observations, the cosmological constant model is still the best one among all the dark energy models. The generalized Chaplygin gas model, the constant w model, and the α dark energy model are worse than the cosmological constant model, but still are good models compared to others. The holographic dark energy model, the new generalized Chaplygin gas model, and the Chevalliear-Polarski-Linder model can still fit the current observations well, but from an economically feasible perspective, they are not so good. The new agegraphic dark energy model, the Dvali-Gabadadze-Porrati model, and the Ricci dark energy model are excluded by the current observations. (orig.)

  12. Rodent model of direct cranial blast injury. (United States)

    Kuehn, Reed; Simard, Philippe F; Driscoll, Ian; Keledjian, Kaspar; Ivanova, Svetlana; Tosun, Cigdem; Williams, Alicia; Bochicchio, Grant; Gerzanich, Volodymyr; Simard, J Marc


    Traumatic brain injury resulting from an explosive blast is one of the most serious wounds suffered by warfighters, yet the effects of explosive blast overpressure directly impacting the head are poorly understood. We developed a rodent model of direct cranial blast injury (dcBI), in which a blast overpressure could be delivered exclusively to the head, precluding indirect brain injury via thoracic transmission of the blast wave. We constructed and validated a Cranium Only Blast Injury Apparatus (COBIA) to deliver blast overpressures generated by detonating .22 caliber cartridges of smokeless powder. Blast waveforms generated by COBIA replicated those recorded within armored vehicles penetrated by munitions. Lethal dcBI (LD(50) ∼ 515 kPa) was associated with: (1) apparent brainstem failure, characterized by immediate opisthotonus and apnea leading to cardiac arrest that could not be overcome by cardiopulmonary resuscitation; (2) widespread subarachnoid hemorrhages without cortical contusions or intracerebral or intraventricular hemorrhages; and (3) no pulmonary abnormalities. Sub-lethal dcBI was associated with: (1) apnea lasting up to 15 sec, with transient abnormalities in oxygen saturation; (2) very few delayed deaths; (3) subarachnoid hemorrhages, especially in the path of the blast wave; (4) abnormal immunolabeling for IgG, cleaved caspase-3, and β-amyloid precursor protein (β-APP), and staining for Fluoro-Jade C, all in deep brain regions away from the subarachnoid hemorrhages, but in the path of the blast wave; and (5) abnormalities on the accelerating Rotarod that persisted for the 1 week period of observation. We conclude that exposure of the head alone to severe explosive blast predisposes to significant neurological dysfunction.

  13. 2D and 3D Modeling Comparison


    Gaidyte, Rita


    Many inventors and companies still use 2D drawings and are starting to realize a 3D design because 3D modeling can save time and money. In this project I am going to compare 2D and 3D drawings and modeling. 2D modeling and 3D modeling have advantages and disadvantages. For this comparison I made 2D and 3D models using AutoCAD, Autodesk Revit Architectural and Revit MEP software. So, I am going to compare CAD (Computer-aided design) and BIM (Building Information Modeling) technologies, beca...

  14. Direct Comparison of Particle-Tracking and Sectional Approaches for Shock Driven Flows

    Directory of Open Access Journals (Sweden)

    Douglas A. Schwer


    Full Text Available Dispersed-phase flows are important for a wide variety of problems, and several numerical approaches for the solution of dispersed-phase flows have been proposed and implemented in the past. The present research implements two popular approaches to dispersed-phase flows: the Lagrangian particle-tracking approach and the Eulerian sectional approach. A direct comparison between the two methods is made for a range of shock driven seeded flow-fields. First, different drag models are investigated using the particle-tracking method for a range of conditions, and then direct comparisons between the two methods are made for shock speed attenuation and shock-wave profiles. In addition, resolution requirements are investigated to determine the number of sections and the number of particles required to obtain good agreement between the methods, and then two-dimensional simulations are done to investigate the effect of each method on more complicated flow-fields. Results showed both methods can be used to obtain very similar results, although each method has benefits and drawbacks. The glass particles were then replaced with water droplets, and the effect of vaporization and droplet breakup were then investigated. Although vaporization was well represented with the sectional approach, different droplet breakup models had to be implemented for the different approaches, with some significant differences in the resultant droplet distributions. The reason for this is that breakup models require a droplet deformation time before breaking up, and thus a droplet history. This droplet history is difficult to implement in sectional approaches (and Eulerian methods in general, and so the breakup model must be changed. Similar profiles could be reproduced with the sectional method, but significant differences persisted. The results did show, however, that the Eulerian sectional approach is a viable method for computing complex, multi-dimensional flow-fields and can

  15. Comparison of hormonally induced sex direction in two strains of ...

    African Journals Online (AJOL)

    There was no significant difference (P < 0.05) in percentage sex direction in the two strains. Nucleated oocytes could be distinguished clearly from oogonia in fish weighing 2 g and above. Gonadal development however, commenced earlier in the TR strain group with nucleated oocytes being observed from fish of 2 g ...

  16. Comparison of direct and precipitation methods for the estimation of ...

    African Journals Online (AJOL)

    Background: There is increase in use of direct assays for analysis of high and low density lipoprotein cholesterol by clinical laboratories despite differences in performance characteristics with conventional precipitation methods. Calculation of low density lipoprotein cholesterol in precipitation methods is based on total ...

  17. A comparison of direct and indirect analytical methods of computing ...

    African Journals Online (AJOL)

    The first step in the analysis of gravity anomalies for mineral exploration is the extraction of residual gravity anomalies from the observed gravity anomalies. This can be achieved by graphical or analytical methods. Generally, direct and indirect analytical methods are considered better than graphical methods. Telford et al ...

  18. Toward a direct comparison of field and laboratory goniometer measurements

    NARCIS (Netherlands)

    Dangel, S.; Verstraete, M.; Schopfer, J.; Kneubuehler, M.; Schaepman, M.E.; Itten, K.I.


    Field and laboratory goniometers are widely used in the remote sensing community to assess spectrodirectional reflection properties of selected targets. Even when the same target and goniometer system are used, field and laboratory results cannot directly be compared due to inherent differences,

  19. Estimates of oceanic surface wind speed and direction using orthogonal beam scatterometer measurements and comparison of recent sea scattering theories (United States)

    Moore, R. K.; Fung, A. K.; Dome, G. J.; Birrer, I. J.


    The wind direction properties of radar backscatter from the sea were empirically modelled using a cosine Fourier series through the 4th harmonic in wind direction (referenced to upwind). A comparison with 1975 JONSWAP (Joint North Sea Wave Project) scatterometer data, at incidence angles of 40 and 65, indicates that effects to third and fourth harmonics are negligible. Another important result is that the Fourier coefficients through the second harmonic are related to wind speed by a power law expression. A technique is also proposed to estimate the wind speed and direction over the ocean from two orthogonal scattering measurements. A comparison between two different types of sea scatter theories, one type presented by the work of Wright and the other by that of Chan and Fung, was made with recent scatterometer measurements. It demonstrates that a complete scattering model must include some provisions for the anisotropic characteristics of the sea scatter, and use a sea spectrum which depends upon wind speed.

  20. Cirrus Parcel Model Comparison Phase 2 (United States)

    Lin, Ruei-Fong; Starr, David OC.; DeMott, Paul J.; Cotton, Richard; Jensen, Eric; Kaercher, Bernd; Liu, Xiaohong


    The Cirrus Parcel Model Comparison (CPMC) project, a project of the GEWEX Cloud System Study Working Group on cirrus clouds (GCSS WG2), is an international effort to advance our knowledge of numerical simulations of cirrus cloud initiation. This project was done in two phases. In Phase 1 of CPMC, the critical components determining the predicted cloud microphysical properties were identified using parcel models in which the aerosol and ice crystal size distributions are explicitly resolved, the formulation of the homogeneous freezing of aqueous solution droplets, especially the gradient of nucleation rate with respect to solution concentration; aerosol growth modeling; and the mass accommodation coefficient of water vapor on ice surface (the deposition coefficient). In Phase 1, all simulations were conducted using a given background aerosol distribution. To complete the comparison study, participant model responses to a range of background aerosol distributions are investigated in Phase 2.

  1. Modeling of the Direct Current Generator Including the Magnetic Saturation and Temperature Effects

    Directory of Open Access Journals (Sweden)

    Alfonso J. Mercado-Samur


    Full Text Available In this paper the inclusion of temperature effect on the field resistance on the direct current generator model DC1A, which is valid to stability studies is proposed. First, the linear generator model is presented, after the effect of magnetic saturation and the change in the resistance value due to temperature produced by the field current are included. The comparison of experimental results and model simulations to validate the model is used. A direct current generator model which is a better representation of the generator is obtained. Visual comparison between simulations and experimental results shows the success of the proposed model, because it presents the lowest error of the compared models. The accuracy of the proposed model is observed via Modified Normalized Sum of Squared Errors index equal to 3.8979%.

  2. Thermal sensation models: a systematic comparison. (United States)

    Koelblen, B; Psikuta, A; Bogdan, A; Annaheim, S; Rossi, R M


    Thermal sensation models, capable of predicting human's perception of thermal surroundings, are commonly used to assess given indoor conditions. These models differ in many aspects, such as the number and type of input conditions, the range of conditions in which the models can be applied, and the complexity of equations. Moreover, the models are associated with various thermal sensation scales. In this study, a systematic comparison of seven existing thermal sensation models has been performed with regard to exposures including various air temperatures, clothing thermal insulation, and metabolic rate values after a careful investigation of the models' range of applicability. Thermo-physiological data needed as input for some of the models were obtained from a mathematical model for human physiological responses. The comparison showed differences between models' predictions for the analyzed conditions, mostly higher than typical intersubject differences in votes. Therefore, it can be concluded that the choice of model strongly influences the assessment of indoor spaces. The issue of comparing different thermal sensation scales has also been discussed. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  3. Comparison of the Economic Factors that Influence Foreign Direct ...

    African Journals Online (AJOL)

    The study determined the compound growth rate of FDI and the factors influencing its inflow in India and Nigeria. The study showed that the time series data were non-stationary but differenced stationary and their cointegration residual and error correction model regression showed a long-term relationship and a same time ...

  4. Case study: Comparison of motivation for achieving higher performance between self-directed and manager-directed aerospace engineering teams (United States)

    Erlick, Katherine

    "The stereotype of engineers is that they are not people oriented; the stereotype implies that engineers would not work well in teams---that their task emphasis is a solo venture and does not encourage social aspects of collaboration" (Miner & Beyerlein, 1999, p. 16). The problem is determining the best method of providing a motivating environment where design engineers may contribute within a team in order to achieve higher performance in the organization. Theoretically, self-directed work teams perform at higher levels. But, allowing a design engineer to contribute to the team while still maintaining his or her anonymity is the key to success. Therefore, a motivating environment must be established to encourage greater self-actualization in design engineers. The purpose of this study is to determine the favorable motivational environment for design engineers and describe the comparison between two aerospace design-engineering teams: one self-directed and the other manager directed. Following the comparison, this study identified whether self-direction or manager-direction provides the favorable motivational environment for operating as a team in pursuit of achieving higher performance. The methodology used in this research was the case study focusing on the team's levels of job satisfaction and potential for higher performance. The collection of data came from three sources, (a) surveys, (b) researcher observer journal and (c) collection of artifacts. The surveys provided information regarding personal behavior characteristics, potentiality for higher performance and motivational attributes. The researcher journal provided information regarding team dynamics, individual interaction, conflict and conflict resolution. The milestone for performance was based on the collection of artifacts from the two teams. The findings from this study illustrated that whether the team was manager-directed or self-directed does not appear to influence the needs and wants of the


    Energy Technology Data Exchange (ETDEWEB)

    Arregui, I.; Asensio Ramos, A. [Instituto de Astrofísica de Canarias, Vía Láctea s/n, E-38205 La Laguna, Tenerife (Spain); Soler, R., E-mail: [Solar Physics Group, Departament de Física, Universitat de les Illes Balears, E-07122 Palma de Mallorca (Spain)


    The spatial variation of physical quantities, such as the mass density, across solar atmospheric waveguides governs the timescales and spatial scales for wave damping and energy dissipation. The direct measurement of the spatial distribution of density, however, is difficult, and indirect seismology inversion methods have been suggested as an alternative. We applied Bayesian inference, model comparison, and model-averaging techniques to the inference of the cross-field density structuring in solar magnetic waveguides using information on periods and damping times for resonantly damped magnetohydrodynamic transverse kink oscillations. Three commonly employed alternative profiles were used to model the variation of the mass density across the waveguide boundary. Parameter inference enabled us to obtain information on physical quantities such as the Alfvén travel time, the density contrast, and the transverse inhomogeneity length scale. The inference results from alternative density models were compared and their differences quantified. Then, the relative plausibility of the considered models was assessed by performing model comparison. Our results indicate that the evidence in favor of any of the three models is minimal, unless the oscillations are strongly damped. In such a circumstance, the application of model-averaging techniques enables the computation of an evidence-weighted inference that takes into account the plausibility of each model in the calculation of a combined inversion for the unknown physical parameters.

  6. Comparison of CME radial velocities from a flux rope model and an ice cream cone model (United States)

    Kim, T.; Moon, Y.; Na, H.


    Coronal Mass Ejections (CMEs) on the Sun are the largest energy release process in the solar system and act as the primary driver of geomagnetic storms and other space weather phenomena on the Earth. So it is very important to infer their directions, velocities and three-dimensional structures. In this study, we choose two different models to infer radial velocities of halo CMEs since 2008 : (1) an ice cream cone model by Xue et al (2005) using SOHO/LASCO data, (2) a flux rope model by Thernisien et al. (2009) using the STEREO/SECCHI data. In addition, we use another flux rope model in which the separation angle of flux rope is zero, which is morphologically similar to the ice cream cone model. The comparison shows that the CME radial velocities from among each model have very good correlations (R>0.9). We will extending this comparison to other partial CMEs observed by STEREO and SOHO.

  7. Nonlinear dynamics new directions models and applications

    CERN Document Server

    Ugalde, Edgardo


    This book, along with its companion volume, Nonlinear Dynamics New Directions: Theoretical Aspects, covers topics ranging from fractal analysis to very specific applications of the theory of dynamical systems to biology. This second volume contains mostly new applications of the theory of dynamical systems to both engineering and biology. The first volume is devoted to fundamental aspects and includes a number of important new contributions as well as some review articles that emphasize new development prospects. The topics addressed in the two volumes include a rigorous treatment of fluctuations in dynamical systems, topics in fractal analysis, studies of the transient dynamics in biological networks, synchronization in lasers, and control of chaotic systems, among others. This book also: ·         Develops applications of nonlinear dynamics on a diversity of topics such as patterns of synchrony in neuronal networks, laser synchronization, control of chaotic systems, and the study of transient dynam...

  8. Comparison of Power Generating Systems Using Feedback Effect Modeling

    International Nuclear Information System (INIS)

    Kim, Seong Ho; Kim, Kil Yoo; Kim, Tae Woon


    Comparative assessment of various power systems can be treated as a multicriteria decision-making (MCDM) problem. In reality, there is interdependence among decision elements (e.g., decision goal, decision criteria, and decision alternatives). In our previous work, using an analytic hierarchy process (AHP) technique, a comprehensive assessment framework for national power systems has been developed. It was assumed in the AHP modeling that there is no interdependence among decision elements. In the present work, one of interdependence phenomena, feedback effect, is investigated in the context of network structures instead of one-way directional tree structures. Moreover, attitudes of decision-makers can be incorporated into the feedback effect modeling. The main objectives of this work are to develop a feedback effect modeling using an analytic network process (ANP) technique and to demonstrate the feedback effect using a numerical example in comparison to the hierarchy model

  9. Comparison of Power Generating Systems Using Feedback Effect Modeling

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Seong Ho; Kim, Kil Yoo; Kim, Tae Woon [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)


    Comparative assessment of various power systems can be treated as a multicriteria decision-making (MCDM) problem. In reality, there is interdependence among decision elements (e.g., decision goal, decision criteria, and decision alternatives). In our previous work, using an analytic hierarchy process (AHP) technique, a comprehensive assessment framework for national power systems has been developed. It was assumed in the AHP modeling that there is no interdependence among decision elements. In the present work, one of interdependence phenomena, feedback effect, is investigated in the context of network structures instead of one-way directional tree structures. Moreover, attitudes of decision-makers can be incorporated into the feedback effect modeling. The main objectives of this work are to develop a feedback effect modeling using an analytic network process (ANP) technique and to demonstrate the feedback effect using a numerical example in comparison to the hierarchy model.

  10. The Aalborg Model and participant directed learning

    DEFF Research Database (Denmark)

    Qvist, Palle


    Preparing students for a life as active citizens in a democratic society is one of the aims within the Bologna process. The Council of Europe has also stressed the importance of focus on democracy in Higher Education. Higher Education is seen as important to develop a democratic culture among...... students. Teaching democracy should be promoted in lessons and curricula. Creating democratic learning systems in institutions of higher education could be the answer to reaching the aim related to democracy. The Aalborg Model practised at Aalborg University is a learning system which has collaborative...

  11. Comparison of Spatiotemporal Fusion Models: A Review

    Directory of Open Access Journals (Sweden)

    Bin Chen


    Full Text Available Simultaneously capturing spatial and temporal dynamics is always a challenge for the remote sensing community. Spatiotemporal fusion has gained wide interest in various applications for its superiority in integrating both fine spatial resolution and frequent temporal coverage. Though many advances have been made in spatiotemporal fusion model development and applications in the past decade, a unified comparison among existing fusion models is still limited. In this research, we classify the models into three categories: transformation-based, reconstruction-based, and learning-based models. The objective of this study is to (i compare four fusion models (STARFM, ESTARFM, ISTAFM, and SPSTFM under a one Landsat-MODIS (L-M pair prediction mode and two L-M pair prediction mode using time-series datasets from the Coleambally irrigation area and Poyang Lake wetland; (ii quantitatively assess prediction accuracy considering spatiotemporal comparability, landscape heterogeneity, and model parameter selection; and (iii discuss the advantages and disadvantages of the three categories of spatiotemporal fusion models.

  12. Comparison of Direct Solar Energy to Resistance Heating for Carbothermal Reduction of Regolith (United States)

    Muscatello, Anthony C.; Gustafson, Robert J.


    A comparison of two methods of delivering thermal energy to regolith for the carbo thermal reduction process has been performed. The comparison concludes that electrical resistance heating is superior to direct solar energy via solar concentrators for the following reasons: (1) the resistance heating method can process approximately 12 times as much regolith using the same amount of thermal energy as the direct solar energy method because of superior thermal insulation; (2) the resistance heating method is more adaptable to nearer-term robotic exploration precursor missions because it does not require a solar concentrator system; (3) crucible-based methods are more easily adapted to separation of iron metal and glass by-products than direct solar energy because the melt can be poured directly after processing instead of being remelted; and (4) even with projected improvements in the mass of solar concentrators, projected photovoltaic system masses are expected to be even lower.

  13. Comparison direction and comparison dimension among disabled individuals: Towards a refined conceptualization of social comparison under stress

    NARCIS (Netherlands)

    Buunk, Bram

    In a sample of 168 Dutch individual falling under the Disablement Insurance Act, it was found that (a) uncertainty and frustration were related to a need for social comparison; (b) the desire for information about similar others was stronger than the desire for affiliation with such others; (c) the

  14. Visualization and direct comparison of large displacements using difference holographic interferometry

    International Nuclear Information System (INIS)

    Necati Ecevit, F.; Aydin, R.


    The difference holographic interferometry provides the possibility of direct comparison of large displacements and deformations of two similar but different objects by application of a special kind of illumination. In this work, the principles of the difference holographic interferometry and the experimental results obtained by applying the single beam technique to large displacements is presented. (author). 10 refs, 4 figs

  15. Comparison of Electric Karting Modelling Using Matlab®/Simulink® Software


    Didi Istardi


    Electric karting was modelled for efficiency and energy consumption study. The model includes models of battery, power electronics converter, electric motor, and vehicle dynamic of a typical 48 seconds track driving schedule in Europe competition. The regenerative braking energy was also considered in simulation. The comparison of different type of electric motors – direct current (DC) motor, induction motor, permanent magnet synchronous motor (PMSM), brushless direct current motor (BLDC), an...

  16. Achievement Goal Orientations and Adolescents’ Subjective Well-Being in School: The Mediating Roles of Academic Social Comparison Directions (United States)

    Tian, Lili; Yu, Tingting; Huebner, E. Scott


    The purpose of this study was to examine the multiple mediational roles of academic social comparison directions (upward academic social comparison and downward academic social comparison) on the relationships between achievement goal orientations (i.e., mastery goals, performance-approach goals, and performance-avoidance goals) and subjective well-being (SWB) in school (school satisfaction, school affect) in adolescent students in China. A total of 883 Chinese adolescent students (430 males; Mean age = 12.99) completed a multi-measure questionnaire. Structural equation modeling was used to examine the hypotheses. Results indicated that (1) mastery goal orientations and performance-approach goal orientations both showed a statistically significant, positive correlation with SWB in school whereas performance-avoidance goal orientations showed a statistically significant, negative correlation with SWB in school among adolescents; (2) upward academic social comparisons mediated the relation between the three types of achievement goal orientations (i.e., mastery goals, performance-approach goals, and performance-avoidance goals) and SWB in school; (3) downward academic social comparisons mediated the relation between mastery goal orientations and SWB in school as well as the relation between performance-avoidance goal orientations and SWB in school. The findings suggest possible important cultural differences in the antecedents of SWB in school in adolescent students in China compared to adolescent students in Western nations. PMID:28197109

  17. Achievement Goal Orientations and Adolescents' Subjective Well-Being in School: The Mediating Roles of Academic Social Comparison Directions. (United States)

    Tian, Lili; Yu, Tingting; Huebner, E Scott


    The purpose of this study was to examine the multiple mediational roles of academic social comparison directions (upward academic social comparison and downward academic social comparison) on the relationships between achievement goal orientations (i.e., mastery goals, performance-approach goals, and performance-avoidance goals) and subjective well-being (SWB) in school (school satisfaction, school affect) in adolescent students in China. A total of 883 Chinese adolescent students (430 males; Mean age = 12.99) completed a multi-measure questionnaire. Structural equation modeling was used to examine the hypotheses. Results indicated that (1) mastery goal orientations and performance-approach goal orientations both showed a statistically significant, positive correlation with SWB in school whereas performance-avoidance goal orientations showed a statistically significant, negative correlation with SWB in school among adolescents; (2) upward academic social comparisons mediated the relation between the three types of achievement goal orientations (i.e., mastery goals, performance-approach goals, and performance-avoidance goals) and SWB in school; (3) downward academic social comparisons mediated the relation between mastery goal orientations and SWB in school as well as the relation between performance-avoidance goal orientations and SWB in school. The findings suggest possible important cultural differences in the antecedents of SWB in school in adolescent students in China compared to adolescent students in Western nations.

  18. Wind tunnel modeling of roadways: Comparison with mathematical models

    International Nuclear Information System (INIS)

    Heidorn, K.; Davies, A.E.; Murphy, M.C.


    The assessment of air quality impacts from roadways is a major concern to urban planners. In order to assess future road and building configurations, a number of techniques have been developed including mathematical models, which simulate traffic emissions and atmospheric dispersion through a series of mathematical relationships and physical models. The latter models simulate emissions and dispersion through scaling of these processes in a wind tunnel. Two roadway mathematical models, HIWAY-2 and CALINE-4, were applied to a proposed development in a large urban area. Physical modeling procedures developed by Rowan Williams Davies and Irwin Inc. (RWDI) in the form of line source simulators were also applied, and the resulting carbon monoxide concentrations were compared. The results indicated a factor of two agreement between the mathematical and physical models. The physical model, however, reacted to change in building massing and configuration. The mathematical models did not, since no provision for such changes was included in the mathematical models. In general, the RWDI model resulted in higher concentrations than either HIWAY-2 or CALINE-4. Where there was underprediction, it was often due to shielding of the receptor by surrounding buildings. Comparison of these three models with the CALTRANS Tracer Dispersion Experiment showed good results although concentrations were consistently underpredicted

  19. Left auditory cortex is involved in pairwise comparisons of the direction of frequency modulated tones

    Directory of Open Access Journals (Sweden)

    Nicole eAngenstein


    Full Text Available Evaluating series of complex sounds like those in speech and music requires sequential comparisons to extract task-relevant relations between subsequent sounds. With the present functional magnetic resonance imaging (fMRI study, we investigated whether sequential comparison of a specific acoustic feature within pairs of tones leads to a change in lateralized processing in the auditory cortex of humans. For this we used the active categorization of the direction (up versus down of slow frequency modulated (FM tones. Several studies suggest that this task is mainly processed in the right auditory cortex. These studies, however, tested only the categorization of the FM direction of each individual tone. In the present study we ask the question whether the right lateralized processing changes when, in addition, the FM direction is compared within pairs of successive tones. For this we use an experimental approach involving contralateral noise presentation in order to explore the contributions made by the left and right auditory cortex in the completion of the auditory task. This method has already been applied to confirm the right-lateralized processing of the FM direction of individual tones. In the present study, the subjects were required to perform, in addition, a sequential comparison of the FM-direction in pairs of tones. The results suggest a division of labor between the two hemispheres such that the FM direction of each individual tone is mainly processed in the right auditory cortex whereas the sequential comparison of this feature between tones in a pair is probably performed in the left auditory cortex.

  20. Comparison between a radio-frequency and direct current glow discharge in argon by a hybrid Monte Carlo-fluid model for electrons, argon ions and fast argon atoms

    NARCIS (Netherlands)

    Bogaerts, A.; Gijbels, R.; W. Goedheer,


    A hybrid Monte Carlo-fluid model has been developed for the electrons, argon ions and fast argon atoms in an argon glow discharge, either operated in the de mode or the capacitively coupled rf mode. Typical working conditions for rf GD-OES are considered, i.e. approximately 6 torr argon gas pressure

  1. Modeling Macrosegregation in Directionally Solidified Aluminum Alloys under Gravitational and Microgravitational Conditions.

    Energy Technology Data Exchange (ETDEWEB)

    Lauer, Mark A.; Poirier, David R.; Erdmann, Robert G.; Tewari, Surendra N.; Madison, Jonathan D


    This report covers the modeling of seven directionally solidified samples, five under normal gravitational conditions and two in microgravity. A model is presented to predict macrosegregation during the melting phases of samples solidified under microgravitational conditions. The results of this model are compared against two samples processed in microgravity and good agreement is found. A second model is presented that captures thermosolutal convection during directional solidification. Results for this model are compared across several experiments and quantitative comparisons are made between the model and the experimentally obtained radial macrosegregation profiles with good agreement being found. Changes in cross section were present in some samples and micrographs of these are qualitatively compared with the results of the simulations. It is found that macrosegregation patterns can be affected by changing the mold material.

  2. How can model comparison help improving species distribution models?

    Directory of Open Access Journals (Sweden)

    Emmanuel Stephan Gritti

    Full Text Available Today, more than ever, robust projections of potential species range shifts are needed to anticipate and mitigate the impacts of climate change on biodiversity and ecosystem services. Such projections are so far provided almost exclusively by correlative species distribution models (correlative SDMs. However, concerns regarding the reliability of their predictive power are growing and several authors call for the development of process-based SDMs. Still, each of these methods presents strengths and weakness which have to be estimated if they are to be reliably used by decision makers. In this study we compare projections of three different SDMs (STASH, LPJ and PHENOFIT that lie in the continuum between correlative models and process-based models for the current distribution of three major European tree species, Fagussylvatica L., Quercusrobur L. and Pinussylvestris L. We compare the consistency of the model simulations using an innovative comparison map profile method, integrating local and multi-scale comparisons. The three models simulate relatively accurately the current distribution of the three species. The process-based model performs almost as well as the correlative model, although parameters of the former are not fitted to the observed species distributions. According to our simulations, species range limits are triggered, at the European scale, by establishment and survival through processes primarily related to phenology and resistance to abiotic stress rather than to growth efficiency. The accuracy of projections of the hybrid and process-based model could however be improved by integrating a more realistic representation of the species resistance to water stress for instance, advocating for pursuing efforts to understand and formulate explicitly the impact of climatic conditions and variations on these processes.

  3. Item Response Modeling of Paired Comparison and Ranking Data (United States)

    Maydeu-Olivares, Alberto; Brown, Anna


    The comparative format used in ranking and paired comparisons tasks can significantly reduce the impact of uniform response biases typically associated with rating scales. Thurstone's (1927, 1931) model provides a powerful framework for modeling comparative data such as paired comparisons and rankings. Although Thurstonian models are generally…

  4. A Model of FPGA-based Direct Torque Controller


    Auzani Jidin; Aiman Zakwan Jidin; Nik Rumzi Nik Idris; Tole Sutikno


    This paper presents a generic model of a fully FPGA-based direct torque controller. This model is developed using two’s-complement fixed-point format approaches, in register-transfer-level (RTL) VHDL abstraction for minimizing calculation errors and consuming hardware resource usage. Therefore, the model is universal and can be implemented for all FPGA types. The model is prepared for fast computation, without using of CORDIC algorithm, a soft-core CPU, a transformation from Cartesian-to-pola...

  5. Drift-modeling and monitoring comparisons

    International Nuclear Information System (INIS)

    Chen, N.C.J.; Hanna, S.R.


    Congress is looking into the conglomeration of nuclear reactors into energy centers of limited area. Drift from cooling towers can corrode and damage structures in the immediate vicinity of the towers, cause a public nuisance if located near parking lots or high-density traffic areas, and endanger local vegetation. The estimation of salt deposition has relied primarily on predictions from a variety of models, with very few direct measurements. One of the major efforts in our program is to evaluate the assumptions, limitations, and applicabilities of various analytical models for drift deposition prediction. Several drift deposition models are compared using a set of standard input conditions. The predicted maximum drift deposition differs by two orders of magnitude, and the downwind locations of the maximum differ by one order of magnitude. The discrepancies are attributed mainly to different assumptions in the models regarding the initial effective height of the droplets. Current programs in which drift characteristics at the tower mouth and drift deposition downwind of the tower are being measured are summarized. At the present time, drift deposition measurements, sufficiently comprehensive for model verifications, are unavailable. Hopefully, the Chalk Point Program will satisfy this need

  6. Modeling HIV-1 drug resistance as episodic directional selection.

    Directory of Open Access Journals (Sweden)

    Ben Murrell

    Full Text Available The evolution of substitutions conferring drug resistance to HIV-1 is both episodic, occurring when patients are on antiretroviral therapy, and strongly directional, with site-specific resistant residues increasing in frequency over time. While methods exist to detect episodic diversifying selection and continuous directional selection, no evolutionary model combining these two properties has been proposed. We present two models of episodic directional selection (MEDS and EDEPS which allow the a priori specification of lineages expected to have undergone directional selection. The models infer the sites and target residues that were likely subject to directional selection, using either codon or protein sequences. Compared to its null model of episodic diversifying selection, MEDS provides a superior fit to most sites known to be involved in drug resistance, and neither one test for episodic diversifying selection nor another for constant directional selection are able to detect as many true positives as MEDS and EDEPS while maintaining acceptable levels of false positives. This suggests that episodic directional selection is a better description of the process driving the evolution of drug resistance.

  7. Model selection and comparison for independents sinusoids

    DEFF Research Database (Denmark)

    Nielsen, Jesper Kjær; Christensen, Mads Græsbøll; Jensen, Søren Holdt


    In the signal processing literature, many methods have been proposed for estimating the number of sinusoidal basis functions from a noisy data set. The most popular method is the asymptotic MAP criterion, which is sometimes also referred to as the BIC. In this paper, we extend and improve this me....... Through simulations, we demonstrate that the lp-BIC outperforms the asymptotic MAP criterion and other state of the art methods in terms of model selection, de-noising and prediction performance. The simulation code is available online.......In the signal processing literature, many methods have been proposed for estimating the number of sinusoidal basis functions from a noisy data set. The most popular method is the asymptotic MAP criterion, which is sometimes also referred to as the BIC. In this paper, we extend and improve...... this method by considering the problem in a full Bayesian framework instead of the approximate formulation, on which the asymptotic MAP criterion is based. This leads to a new model selection and comparison method, the lp-BIC, whose computational complexity is of the same order as the asymptotic MAP criterion...

  8. Can Direct and Indirect Taxes Be Added for International Comparisons of Competitiveness?


    Hans-Werner Sinn


    While it is usually argued that direct and indirect taxes should be added for meaningful international comparisons of country competitiveness, this paper argues that the opposite may be true. It is possible that a country with a high value-added tax needs a high capital income tax to maintain its international competitiveness and vice verca. Which view is correct depends on which combination of the origin, destination, source and residence principles' prevail and whether or not accelerated de...

  9. Comparison of three-level torque hysteresis controllers for direct torque control


    Beerten, Jef; Verveckken, Jan; Driesen, Johan


    In this paper, a comparison is made between different implementations of the three-level torque comparator for a Direct Torque Control (DTC) based induction motor drive. The DTC scheme controls stator flux and torque by means of hysteresis comparators, respectively a two-level control structure for the stator flux and a three-level comparator for the electromagnetic torque. The standard three-level hysteresis controller has a DC offset torque error. In this paper, an additive implementation i...

  10. Future directions for LDEF ionizing radiation modeling and assessments (United States)

    Armstrong, T. W.; Colborn, B. L.


    A calculational program utilizing data from radiation dosimetry measurements aboard the Long Duration Exposure Facility (LDEF) satellite to reduce the uncertainties in current models defining the ionizing radiation environment is in progress. Most of the effort to date has been on using LDEF radiation dose measurements to evaluate models defining the geomagnetically trapped radiation, which has provided results applicable to radiation design assessments being performed for Space Station Freedom. Plans for future data comparisons, model evaluations, and assessments using additional LDEF data sets (LET spectra, induced radioactivity, and particle spectra) are discussed.

  11. Data-Model Comparison of Pliocene Sea Surface Temperature (United States)

    Dowsett, H. J.; Foley, K.; Robinson, M. M.; Bloemers, J. T.


    The mid-Piacenzian (late Pliocene) climate represents the most geologically recent interval of long-term average warmth and shares similarities with the climate projected for the end of the 21st century. As such, its fossil and sedimentary record represents a natural experiment from which we can gain insight into potential climate change impacts, enabling more informed policy decisions for mitigation and adaptation. We present the first systematic comparison of Pliocene sea surface temperatures (SST) between an ensemble of eight climate model simulations produced as part of PlioMIP (Pliocene Model Intercomparison Project) and the PRISM (Pliocene Research, Interpretation and Synoptic Mapping) Project mean annual SST field. Our results highlight key regional (mid- to high latitude North Atlantic and tropics) and dynamic (upwelling) situations where there is discord between reconstructed SST and the PlioMIP simulations. These differences can lead to improved strategies for both experimental design and temporal refinement of the palaeoenvironmental reconstruction. Scatter plot of multi-model-mean anomalies (squares) and PRISM3 data anomalies (large blue circles) by latitude. Vertical bars on data anomalies represent the variability of warm climate phase within the time-slab at each locality. Small colored circles represent individual model anomalies and show the spread of model estimates about the multi-model-mean. While not directly comparable in terms of the development of the means nor the meaning of variability, this plot provides a first order comparison of the anomalies. Encircled areas are a, PRISM low latitude sites outside of upwelling areas; b, North Atlantic coastal sequences and Mediterranean sites; c, large anomaly PRISM sites from the northern hemisphere. Numbers identify Ocean Drilling Program sites.

  12. Cardinal Direction Relations Query Modeling Based on Geo-Ontology (United States)

    Zhu, X.; Chen, D.; Zhou, C.; Li, M.; Xiao, W.


    Direction relations, as an important spatial relationship, is simply expressed as object prosperity in traditional geo-ontology. The lacking of explicit specifications and reasoning rules of direction relations in geo-ontology result in the difficult or inflexible of spatial reasoning. Also, digital gazetteers provide information on named features, linking the feature's name with its location and its type. Although the location information is incomplete and not exact, the implicit spatial information, for example spatial relationships and spatial scale, can be extract using the appropriate models based on geo-ontology. In this paper, we proposed a novel conceptual framework of direction relations in order to formalize the semantics and implicit information of direction relations, and present an extraction algorithm of implicit information based on previous researches, which will produce a complete query instance of direction relations. At last, the most suitable direction physical model is recommended to calculation module according to relevant rules. And the experimental results show that this direction query model not only extracted the implicit information effectively, but also made a reasonable interpretation for the user's intention.

  13. Macroscopic Modeling of Transport Phenomena in Direct Methanol Fuel Cells

    DEFF Research Database (Denmark)

    Olesen, Anders Christian

    An increasing need for energy efficiency and high energy density has sparked a growing interest in direct methanol fuel cells for portable power applications. This type of fuel cell directly generates electricity from a fuel mixture consisting of methanol and water. Although this technology...... for studying their transport. In this PhD dissertation the macroscopic transport phenomena governing direct methanol fuel cell operation are analyzed, discussed and modeled using the two-fluid approach in the computational fluid dynamics framework of CFX 14. The overall objective of this work is to extend...... the present fundamental understanding of direct methanol fuel cell operation by developing a three-dimensional, two-phase, multi-component, non-isotherm mathematical model including detailed non-ideal thermodynamics, non-equilibrium phase change and non-equilibrium sorption-desorption of methanol and water...

  14. Modeling directional spatio-temporal processes in island biogeography. (United States)

    Carvalho, José C; Cardoso, Pedro; Rigal, François; Triantis, Kostas A; Borges, Paulo A V


    A key challenge in island biogeography is to quantity the role of dispersal in shaping biodiversity patterns among the islands of a given archipelago. Here, we propose such a framework. Dispersal within oceanic archipelagos may be conceptualized as a spatio-temporal process dependent on: (1) the spatial distribution of islands, because the probability of successful dispersal is inversely related to the spatial distance between islands and (2) the chronological sequence of island formation that determines the directional asymmetry of dispersal (hypothesized to be predominantly from older to younger islands). From these premises, directional network models may be constructed, representing putative connections among islands. These models may be translated to eigenfunctions in order to be incorporated into statistical analysis. The framework was tested with 12 datasets from the Hawaii, Azores, and Canaries. The explanatory power of directional network models for explaining species composition patterns, assessed by the Jaccard dissimilarity index, was compared with simpler time-isolation models. The amount of variation explained by the network models ranged from 5.5% (for Coleoptera in Hawaii) to 60.2% (for Pteridophytes in Canary Islands). In relation to the four studied taxa, the variation explained by network models was higher for Pteridophytes in the three archipelagos. By the contrary, small fractions of explained variation were observed for Coleoptera (5.5%) and Araneae (8.6%) in Hawaii. Time-isolation models were, in general, not statistical significant and explained less variation than the equivalent directional network models for all the datasets. Directional network models provide a way for evaluating the spatio-temporal signature of species dispersal. The method allows building scenarios against which hypotheses about dispersal within archipelagos may be tested. The new framework may help to uncover the pathways via which species have colonized the islands of

  15. Target Scattering Metrics: Model-Model and Model-Data Comparisons (United States)


    be suitable for input to classification schemes. The investigated metrics are then applied to model-data comparisons. INTRODUCTION Metrics for...stainless steel replica of artillery shell Table 7. Targets used in the TIER simulations for the metrics study. C. Four Potential Metrics: Four...Four metrics were investigated. The metric, based on 2D cross-correlation, is typically used in classification algorithms. Model-model comparisons

  16. Nonlinear nanophotonic and nanoplasmonic directional couplers: comparison of modelling methods

    Czech Academy of Sciences Publication Activity Database

    Koška, Pavel; Petráček, J.; Kwiecien, P.; Luksch, J.; Richter, I.; Čtyroký, Jiří


    Roč. 47, č. 9 (2015), s. 3201-3212 ISSN 0306-8919 Institutional support: RVO:67985882 Keywords : Integrated optics * All-optical switching * Nanophotonics Subject RIV: JA - Electronics ; Optoelectronics, Electrical Engineering Impact factor: 1.290, year: 2015

  17. Direct tensor rendering using a bidirectional reflectance model (United States)

    Nagasawa, Mikio; Suzuki, Yoshio


    For the multi variable volumetric tensor field visualization, an efficient direct rendering technique without using geometrical primitive is proposed. The bi- directional reflectance shading model is used to map the anisotropy stress shear tensor components in direct volume rendering. We model the sub-pixel-sized microfacet at tensor sampling points. The nine component of 3D tensor field are mapped onto grid deformation, opacity mapping, color specification, and normal directions of these microfacets. The ray integration is executed though these irregular infinitesimal microfacets distribution. This direct tensor rendering was applied for at-a-glance tensor visualization of earthquake simulation. That realized a view of deformed structure, stress distribution, local shear discontinuity and the shock front, integrated in a single image. The characteristic P- and S-wave modes are distinguished in the rendered earthquake simulations. Compared with the glyph representation of tensor features, the direct tensor rendering gives the general and total image of tensor field even for the low resolution pixel planes, because the sampling object is assumed as infinitesimally small. the computational cost of direct tensor rendering is not so high than that of scalar volume rendering because the modifications are only ins hading calculation but not in the ray integration.

  18. Bayesian Model Comparison With the g-Prior

    DEFF Research Database (Denmark)

    Nielsen, Jesper Kjær; Christensen, Mads Græsbøll; Cemgil, Ali Taylan


    Model comparison and selection is an important problem in many model-based signal processing applications. Often, very simple information criteria such as the Akaike information criterion or the Bayesian information criterion are used despite their shortcomings. Compared to these methods, Djuric...... demonstrate that our proposed model comparison and selection rules outperform the traditional information criteria both in terms of detecting the true model and in terms of predicting unobserved data. The simulation code is available online....

  19. Magnetization direction in the Heisenberg model exhibiting fractional Brownian motion

    DEFF Research Database (Denmark)

    Zhang, Zhengping; Mouritsen, Ole G.; Zuckermann, Martin J.


    The temporal magnetization-direction fluctuations in the three-dimensional classical ferromagnetic Heisenberg model have been generated by Monte Carlo simulation and analyzed by the rescaled-range method to yield the Hurst exponent H. A value of H congruent-to 1 has been found to apply in the fer......The temporal magnetization-direction fluctuations in the three-dimensional classical ferromagnetic Heisenberg model have been generated by Monte Carlo simulation and analyzed by the rescaled-range method to yield the Hurst exponent H. A value of H congruent-to 1 has been found to apply...

  20. Distinctions without a difference: direct comparisons of psychotherapies for alcohol use disorders. (United States)

    Imel, Zac E; Wampold, Bruce E; Miller, Scott D; Fleming, Reg R


    To estimate the relative efficacy of alcohol use disorder treatments, the authors meta-analyzed studies that directly compared 2 bona fide psychological treatments. The authors accommodated problems with the inclusion of multiple treatment comparisons by randomly assigning a positive/negative sign to the effect size derived from each comparison and then estimating the extent to which effect sizes were heterogeneous. The authors' primary hypothesis was that the variability in effect sizes of bona fide psychological treatments for alcohol use disorders that were directly compared would be zero. For both alcohol measures and measures of abstinence, analyses indicate that effects were homogenously distributed about zero (I(2) = 10.61, 0.00, respectively), indicating that different treatment comparisons yielded a common effect size that was not significantly different from zero. Analyses also indicate that allegiance accounted for a significant portion of variability in differences between treatments. Implications for the treatment of alcohol use disorders as well as research on the mechanisms responsible for the benefit of treatment are discussed. 2008 APA, all rights reserved

  1. Comparison of performance of simulation models for floor heating

    DEFF Research Database (Denmark)

    Weitzmann, Peter; Svendsen, Svend


    This paper describes the comparison of performance of simulation models for floor heating with different level of detail in the modelling process. The models are compared in an otherwise identical simulation model containing room model, walls, windows, ceiling and ventilation system. By exchanging...

  2. Wind turbine noise modeling : a comparison of modeling methods

    International Nuclear Information System (INIS)

    Wang, L.; Strasser, A.


    All wind turbine arrays must undergo a noise impact assessment. DataKustik GmbH developed the Computer Aided Noise Abatement (Cadna/A) modeling software for calculating noise propagation to meet accepted protocols and international standards such as CONCAWE and ISO 9613 standards. The developer of Cadna/A, recommended the following 3 models for simulating wind turbine noise. These include a disk of point sources; a ring of point sources located at the tip of each blade; and a point source located at the top of the wind turbine tower hub. This paper presented an analytical comparison of the 3 models used for a typical wind turbine with a hub tower containing 3 propeller blades, a drive-train and top-mounted generator, as well as a representative wind farm, using Cadna/A. AUC, ISO and IEC criteria requirements for the meteorological input with Cadna/A for wind farm noise were also discussed. The noise predicting modelling approach was as follows: the simplest model, positioning a single point source at the top of the hub, can be used to predict sound levels for a typical wind turbine if receptors are located 250 m from the hub; a-weighted sound power levels of a wind turbine at cut-in and cut-off wind speed should be used in the models; 20 by 20 or 50 by 50 meter terrain parameters are suitable for large wind farm modeling; and ISO 9613-2 methods are recommended to predict wind farm noise with various metrological inputs based on local conditions. The study showed that the predicted sound level differences of the 3 wind turbine models using Cadna/A are less than 0.2 dB at receptors located greater than 250 m from the wind turbine hub, which fall within the accuracy range of the calculation method. All 3 models of wind turbine noise meet ISO9613-2 standards for noise prediction using Cadna/A. However, the single point source model was found to be the most efficient in terms of modeling run-time among the 3 models. 7 refs., 3 tabs., 15 figs.

  3. Revisiting the direct detection of dark matter in simplified models


    Li, Tong


    In this work we numerically re-examine the loop-induced WIMP-nucleon scattering cross section for the simplified dark matter models and the constraint set by the latest direct detection experiment. We consider a fermion, scalar or vector dark matter component from five simplified models with leptophobic spin-0 mediators coupled only to Standard Model quarks and dark matter particles. The tree-level WIMP-nucleon cross sections in these models are all momentum-suppressed. We calculate the non-s...

  4. A Model of Direct Gauge Mediation of Supersymmetry Breaking

    Energy Technology Data Exchange (ETDEWEB)

    Murayama, H. [Theoretical Physics Group, Lawrence Berkeley National Laboratory, Berkeley, California 94720 (United States)]|[Department of Physics, University of California, Berkeley, California 94720 (United States)


    We present the first phenomenologically viable model of gauge meditation of supersymmetry breaking without a messenger sector or gauge singlet fields. The standard model gauge groups couple directly to the sector which breaks supersymmetry dynamically. Despite the direct coupling, it can preserve perturbative gauge unification thanks to the inverted hierarchy mechanism. There is no dangerous negative contribution to m{sup 2}{sub {tilde q}} , m{sup 2}{sub {tilde l}} due to two-loop renormalization group equation. The potentially nonuniversal supergravity contribution to m{sup 2}{sub {tilde q}} and m{sup 2}{sub {tilde l}} can be suppressed enough. The model is completely chiral, and one does not need to forbid mass terms for the messenger fields by hand. Cosmology of the model is briefly discussed. {copyright} {ital 1997} {ital The American Physical Society}

  5. A Dynamic Growth Model for Flows of Foreign Direct Investment


    Yi-Hui Chiang; Yiming Li; Chih-Young Hung


    In this work, we for the first time study the dynamic flows of the foreign direct investment (FDI) with a dynamic growth theory. We define the FDI flow as a process which transmits throughout a given social system by way of diverse communication channels. In model formulation, seven assumptions are thus proposed and the foreign capital policy of the host country is considered as an external influence; in addition, the investment policy of the investing country is modeled as an internal influe...

  6. Microscopic models for direct inelastic scattering and direct preequilibrium emission: nucleon induced reactions

    Directory of Open Access Journals (Sweden)

    Karataglidis S.


    Full Text Available We have developed microscopic models for nucleon induced inelastic scattering and one-step direct preequilibrium emission. These models are based on reliable effective in-medium two-body interactions and a microscopic description of the ground and excited states of target nuclei. No arbitrary renormalization process enters our analyzes and the predictions are directly compared to experimental data. The nuclear structure information are obtained in the Random Phase Approximation (RPA framework with the Gogny force, which provides accurate descriptions of spherical nuclei without pairing. For medium energy (50-200 MeV proton induced reactions, this approach gives very good predictions for direct inelastic scattering and for the first-step in direct preequilibrium emission. The one-step preequilibrium model has also been extended to fast neutron scattering (10-20 MeV for the 90Zr target described with RPA theory, and for axially deformed nuclei with a simpler description of the excited states (i.e. particle-hole excitations. Predictions of the reaction model reproduce well experimental data for 90Zr. For deformed targets (232Th and 238U, our calculations underestimate the data at high emission energy. The cross section missing for both actinides may stem from the excitation of vibrational states with excitation energies lower than 5 MeV which are not described with incoherent particle-hole excitations. This defect might be cured if the target spectra are described within the Quasi-particle-RPA (QRPA theory recently implemented with the Gogny force.

  7. A Nonstationary Markov Model Detects Directional Evolution in Hymenopteran Morphology. (United States)

    Klopfstein, Seraina; Vilhelmsen, Lars; Ronquist, Fredrik


    Directional evolution has played an important role in shaping the morphological, ecological, and molecular diversity of life. However, standard substitution models assume stationarity of the evolutionary process over the time scale examined, thus impeding the study of directionality. Here we explore a simple, nonstationary model of evolution for discrete data, which assumes that the state frequencies at the root differ from the equilibrium frequencies of the homogeneous evolutionary process along the rest of the tree (i.e., the process is nonstationary, nonreversible, but homogeneous). Within this framework, we develop a Bayesian approach for testing directional versus stationary evolution using a reversible-jump algorithm. Simulations show that when only data from extant taxa are available, the success in inferring directionality is strongly dependent on the evolutionary rate, the shape of the tree, the relative branch lengths, and the number of taxa. Given suitable evolutionary rates (0.1-0.5 expected substitutions between root and tips), accounting for directionality improves tree inference and often allows correct rooting of the tree without the use of an outgroup. As an empirical test, we apply our method to study directional evolution in hymenopteran morphology. We focus on three character systems: wing veins, muscles, and sclerites. We find strong support for a trend toward loss of wing veins and muscles, while stationarity cannot be ruled out for sclerites. Adding fossil and time information in a total-evidence dating approach, we show that accounting for directionality results in more precise estimates not only of the ancestral state at the root of the tree, but also of the divergence times. Our model relaxes the assumption of stationarity and reversibility by adding a minimum of additional parameters, and is thus well suited to studying the nature of the evolutionary process in data sets of limited size, such as morphology and ecology. © The Author

  8. Quantitative comparisons of analogue models of brittle wedge dynamics (United States)

    Schreurs, Guido


    Analogue model experiments are widely used to gain insights into the evolution of geological structures. In this study, we present a direct comparison of experimental results of 14 analogue modelling laboratories using prescribed set-ups. A quantitative analysis of the results will document the variability among models and will allow an appraisal of reproducibility and limits of interpretation. This has direct implications for comparisons between structures in analogue models and natural field examples. All laboratories used the same frictional analogue materials (quartz and corundum sand) and prescribed model-building techniques (sieving and levelling). Although each laboratory used its own experimental apparatus, the same type of self-adhesive foil was used to cover the base and all the walls of the experimental apparatus in order to guarantee identical boundary conditions (i.e. identical shear stresses at the base and walls). Three experimental set-ups using only brittle frictional materials were examined. In each of the three set-ups the model was shortened by a vertical wall, which moved with respect to the fixed base and the three remaining sidewalls. The minimum width of the model (dimension parallel to mobile wall) was also prescribed. In the first experimental set-up, a quartz sand wedge with a surface slope of ˜20° was pushed by a mobile wall. All models conformed to the critical taper theory, maintained a stable surface slope and did not show internal deformation. In the next two experimental set-ups, a horizontal sand pack consisting of alternating quartz sand and corundum sand layers was shortened from one side by the mobile wall. In one of the set-ups a thin rigid sheet covered part of the model base and was attached to the mobile wall (i.e. a basal velocity discontinuity distant from the mobile wall). In the other set-up a basal rigid sheet was absent and the basal velocity discontinuity was located at the mobile wall. In both types of experiments

  9. A direct comparison of protein structure in the gas and solution phase: the Trp-cage

    DEFF Research Database (Denmark)

    Patriksson, Alexandra; Adams, Christopher M; Kjeldsen, Frank


    Molecular dynamics simulations of zwitterions of the Trp-cage protein in the gas phase show that the most stable ion in vacuo has preserved the charge locations acquired in solution. A direct comparison of the gas and solution-phase structures reveals that, despite the similarity in charge location......, there is significant difference in the structures, with a substantial increase in hydrogen bonds and exposure of hydrophobic parts in the gas phase. The structure of the salt bridge in the gas phase is also much more stable than in the (experimental) solution structure....

  10. Direct Numerical Simulation of Fracture Behaviour for Random Short Wood Fibres Reinforced Composites, Comparison with Digital Image Correlation Experiments

    Directory of Open Access Journals (Sweden)

    Brillaud J.


    Full Text Available The work is to predict fracture behaviour of bio-composites from the tensile properties of its components. In this work, we have realized a direct numerical simulation of fracture behaviour for random short spruce fibers reinforced composites. For calculations, wood fibers have been considered as linear elastic bodies, polypropylene matrix as an elastic-plastic material. Then, numerical results have been compared with experimental results that have been obtained by digital image correlation. This comparison indicates that random fiber FE model of random short spruce fibers reinforced composites can be able to fairly reflect the influence of random fibers microstructure in the composite on its fracture behavior. The calculation of both random fiber and homogeneous FE model and their comparison with experiments show that the average values of J-integral in a region in the front of the crack tip from both numerical FE models are in good agreement with the average J value of DIC experiment in the same region when the numerical and experimental CT specimens of the short spruce fiber reinforced composite are subjected to the same extension at their loading point.

  11. Direction selectivity in a model of the starburst amacrine cell. (United States)

    Tukker, John J; Taylor, W Rowland; Smith, Robert G


    The starburst amacrine cell (SBAC), found in all mammalian retinas, is thought to provide the directional inhibitory input recorded in On-Off direction-selective ganglion cells (DSGCs). While voltage recordings from the somas of SBACs have not shown robust direction selectivity (DS), the dendritic tips of these cells display direction-selective calcium signals, even when gamma-aminobutyric acid (GABAa,c) channels are blocked, implying that inhibition is not necessary to generate DS. This suggested that the distinctive morphology of the SBAC could generate a DS signal at the dendritic tips, where most of its synaptic output is located. To explore this possibility, we constructed a compartmental model incorporating realistic morphological structure, passive membrane properties, and excitatory inputs. We found robust DS at the dendritic tips but not at the soma. Two-spot apparent motion and annulus radial motion produced weak DS, but thin bars produced robust DS. For these stimuli, DS was caused by the interaction of a local synaptic input signal with a temporally delayed "global" signal, that is, an excitatory postsynaptic potential (EPSP) that spread from the activated inputs into the soma and throughout the dendritic tree. In the preferred direction the signals in the dendritic tips coincided, allowing summation, whereas in the null direction the local signal preceded the global signal, preventing summation. Sine-wave grating stimuli produced the greatest amount of DS, especially at high velocities and low spatial frequencies. The sine-wave DS responses could be accounted for by a simple mathematical model, which summed phase-shifted signals from soma and dendritic tip. By testing different artificial morphologies, we discovered DS was relatively independent of the morphological details, but depended on having a sufficient number of inputs at the distal tips and a limited electrotonic isolation. Adding voltage-gated calcium channels to the model showed that their

  12. Genomic selection models for directional dominance: an example for litter size in pigs. (United States)

    Varona, Luis; Legarra, Andrés; Herring, William; Vitezica, Zulma G


    The quantitative genetics theory argues that inbreeding depression and heterosis are founded on the existence of directional dominance. However, most procedures for genomic selection that have included dominance effects assumed prior symmetrical distributions. To address this, two alternatives can be considered: (1) assume the mean of dominance effects different from zero, and (2) use skewed distributions for the regularization of dominance effects. The aim of this study was to compare these approaches using two pig datasets and to confirm the presence of directional dominance. Four alternative models were implemented in two datasets of pig litter size that consisted of 13,449 and 11,581 records from 3631 and 2612 sows genotyped with the Illumina PorcineSNP60 BeadChip. The models evaluated included (1) a model that does not consider directional dominance (Model SN), (2) a model with a covariate b for the average individual homozygosity (Model SC), (3) a model with a parameter λ that reflects asymmetry in the context of skewed Gaussian distributions (Model AN), and (4) a model that includes both b and λ (Model Full). The results of the analysis showed that posterior probabilities of a negative b or a positive λ under Models SC and AN were higher than 0.99, which indicate positive directional dominance. This was confirmed with the predictions of inbreeding depression under Models Full, SC and AN, that were higher than in the SN Model. In spite of differences in posterior estimates of variance components between models, comparison of models based on LogCPO and DIC indicated that Model SC provided the best fit for the two datasets analyzed. Our results confirmed the presence of positive directional dominance for pig litter size and suggested that it should be taken into account when dominance effects are included in genomic evaluation procedures. The consequences of ignoring directional dominance may affect predictions of breeding values and can lead to biased

  13. Modeling and Simulation of the Direct Methanol Fuel Cell (United States)

    Wohr, M.; Narayanan, S. R.; Halpert, G.


    From intro.: The direct methanol liquid feed fuel cell uses aqueous solutions of methanol as fuel and oxygen or air as the oxidant and uses an ionically conducting polymer membrane such as Nafion(sup r)117 and the electrolyte. This type of direct oxidation cell is fuel versatile and offers significant advantages in terms of simplicity of design and operation...The present study focuses on the results of a phenomenological model based on current understanding of the various processed operating in these cells.

  14. Evading direct dark matter detection in Higgs portal models (United States)

    Arcadi, Giorgio; Gross, Christian; Lebedev, Oleg; Pokorski, Stefan; Toma, Takashi


    Many models of Higgs portal Dark Matter (DM) find themselves under pressure from increasingly tight direct detection constraints. In the framework of gauge field DM, we study how such bounds can be relaxed while retaining the thermal WIMP paradigm. When the hidden sector gauge symmetry is broken via the Higgs mechanism, the hidden sector generally contains unstable states which are lighter than dark matter. These states provide DM with an efficient annihilation channel. As a result, the DM relic abundance and the direct detection limits are controlled by different parameters, and the two can easily be reconciled. This simple setup realizes the idea of ;secluded; dark matter naturally.

  15. Achievement Goal Orientations and Adolescents’ Subjective Well-Being in School: The Mediating Roles of Academic Social Comparison Directions


    Tian, Lili; Yu, Tingting; Huebner, E. Scott


    The purpose of this study was to examine the multiple mediational roles of academic social comparison directions (upward academic social comparison and downward academic social comparison) on the relationships between achievement goal orientations (i.e., mastery goals, performance-approach goals, and performance-avoidance goals) and subjective well-being (SWB) in school (school satisfaction, school affect) in adolescent students in China. A total of 883 Chinese adolescent students (430 males;...


    International Nuclear Information System (INIS)



    The Multi-Step Direct (MSD) module TRISTAN in the nuclear reaction code EMPIRE has been extended in order to account for nuclear deformation. The new formalism was tested in calculations of neutron emission spectra emitted from the 232 Th(n,xn) reaction. These calculations include vibration-rotational Coupled Channels (CC) for the inelastic scattering to low-lying collective levels, ''deformed'' MSD with quadrupole deformation for inelastic scattering to the continuum, Multi-Step Compound (MSC) and Hauser-Feshbach with advanced treatment of the fission channel. Prompt fission neutrons were also calculated. The comparison with experimental data shows clear improvement over the ''spherical'' MSD calculations and JEFF-3.1 and JENDL-3.3 evaluations

  17. Deformation dependent TUL multi-step direct model

    International Nuclear Information System (INIS)

    Wienke, H.; Capote, R.; Herman, M.; Sin, M.


    The Multi-Step Direct (MSD) module TRISTAN in the nuclear reaction code EMPIRE has been extended to account for nuclear deformation. The new formalism was tested in calculations of neutron emission spectra emitted from the 232 Th(n,xn) reaction. These calculations include vibration-rotational Coupled Channels (CC) for the inelastic scattering to low-lying collective levels, 'deformed' MSD with quadrupole deformation for inelastic scattering to the continuum, Multi-Step Compound (MSC) and Hauser-Feshbach with advanced treatment of the fission channel. Prompt fission neutrons were also calculated. The comparison with experimental data shows clear improvement over the 'spherical' MSD calculations and JEFF-3.1 and JENDL-3.3 evaluations. (authors)

  18. Study of the standard direct costs of various techniques of advanced endoscopy. Comparison with surgical alternatives. (United States)

    Loras, Carme; Mayor, Vicenç; Fernández-Bañares, Fernando; Esteve, Maria


    The complexity of endoscopy has carried out an increase in cost that has a direct effect on the healthcare systems. However, few studies have analyzed the cost of advanced endoscopic procedures (AEP). To carry out a calculation of the standard direct costs of AEP, and to make a financial comparison with their surgical alternatives. Calculation of the standard direct cost in carrying out each procedure. An endoscopist detailed the time, personnel, materials, consumables, recovery room time, stents, pathology and medication used. The cost of surgical procedures was the average cost recorded in the hospital. Thirty-eight AEP were analyzed. The technique showing lowest cost was gastroscopy + APC (€116.57), while that with greatest cost was ERCP with cholangioscopy + stent placement (€5083.65). Some 34.2% of the procedures registered average costs of €1000-2000. In 57% of cases, the endoscopic alternative was 2-5 times more cost-efficient than surgery, in 31% of cases indistinguishable or up to 1.4 times more costly. Standard direct cost of the majority of AEP is reported using a methodology that enables easy application in other centers. For the most part, endoscopic procedures are more cost-efficient than the corresponding surgical procedure. Copyright © 2018 The Author(s). Published by Elsevier Ltd.. All rights reserved.

  19. Numerical comparisons of ground motion predictions with kinematic rupture modeling (United States)

    Yuan, Y. O.; Zurek, B.; Liu, F.; deMartin, B.; Lacasse, M. D.


    Recent advances in large-scale wave simulators allow for the computation of seismograms at unprecedented levels of detail and for areas sufficiently large to be relevant to small regional studies. In some instances, detailed information of the mechanical properties of the subsurface has been obtained from seismic exploration surveys, well data, and core analysis. Using kinematic rupture modeling, this information can be used with a wave propagation simulator to predict the ground motion that would result from an assumed fault rupture. The purpose of this work is to explore the limits of wave propagation simulators for modeling ground motion in different settings, and in particular, to explore the numerical accuracy of different methods in the presence of features that are challenging to simulate such as topography, low-velocity surface layers, and shallow sources. In the main part of this work, we use a variety of synthetic three-dimensional models and compare the relative costs and benefits of different numerical discretization methods in computing the seismograms of realistic-size models. The finite-difference method, the discontinuous-Galerkin method, and the spectral-element method are compared for a range of synthetic models having different levels of complexity such as topography, large subsurface features, low-velocity surface layers, and the location and characteristics of fault ruptures represented as an array of seismic sources. While some previous studies have already demonstrated that unstructured-mesh methods can sometimes tackle complex problems (Moczo et al.), we investigate the trade-off between unstructured-mesh methods and regular-grid methods for a broad range of models and source configurations. Finally, for comparison, our direct simulation results are briefly contrasted with those predicted by a few phenomenological ground-motion prediction equations, and a workflow for accurately predicting ground motion is proposed.

  20. Direct containment heating models in the CONTAIN code

    Energy Technology Data Exchange (ETDEWEB)

    Washington, K.E.; Williams, D.C.


    The potential exists in a nuclear reactor core melt severe accident for molten core debris to be dispersed under high pressure into the containment building. If this occurs, the set of phenomena that result in the transfer of energy to the containment atmosphere and its surroundings is referred to as direct containment heating (DCH). Because of the potential for DCH to lead to early containment failure, the U.S. Nuclear Regulatory Commission (USNRC) has sponsored an extensive research program consisting of experimental, analytical, and risk integration components. An important element of the analytical research has been the development and assessment of direct containment heating models in the CONTAIN code. This report documents the DCH models in the CONTAIN code. DCH models in CONTAIN for representing debris transport, trapping, chemical reactions, and heat transfer from debris to the containment atmosphere and surroundings are described. The descriptions include the governing equations and input instructions in CONTAIN unique to performing DCH calculations. Modifications made to the combustion models in CONTAIN for representing the combustion of DCH-produced and pre-existing hydrogen under DCH conditions are also described. Input table options for representing the discharge of debris from the RPV and the entrainment phase of the DCH process are also described. A sample calculation is presented to demonstrate the functionality of the models. The results show that reasonable behavior is obtained when the models are used to predict the sixth Zion geometry integral effects test at 1/10th scale.

  1. Lattice models of directed and semiflexible polymers in anisotropic environment

    International Nuclear Information System (INIS)

    Haydukivska, K; Blavatska, V


    We study the conformational properties of polymers in presence of extended columnar defects of parallel orientation. Two classes of macromolecules are considered: the so-called partially directed polymers with preferred orientation along direction of the external stretching field and semiflexible polymers. We are working within the frames of lattice models: partially directed self-avoiding walks (PDSAWs) and biased self-avoiding walks (BSAWs). Our numerical analysis of PDSAWs reveals, that competition between the stretching field and anisotropy caused by presence of extended defects leads to existing of three characteristic length scales in the system. At each fixed concentration of disorder we found a transition point, where the influence of extended defects is exactly counterbalanced by the stretching field. Numerical simulations of BSAWs in anisotropic environment reveal an increase of polymer stiffness. In particular, the persistence length of semiflexible polymers increases in presence of disorder. (paper)


    Directory of Open Access Journals (Sweden)

    Slavko Arsovski


    Full Text Available The basic subject of this work is the model of new approach impact on quality and safety products, and competency of our companies. This work represents real hypothesis on the basis of expert's experiences, in regard to that the infrastructure with using new approach directives wasn't examined until now, it isn't known which product or industry of Serbia is related to directives of the new approach and CE mark, and it is not known which are effects of the use of the CE mark. This work should indicate existing quality reserves and product's safety, the level of possible competency improvement and increasing the profit by discharging new approach directive requires.

  3. Induction and direct resistance heating theory and numerical modeling

    CERN Document Server

    Lupi, Sergio; Aliferov, Aleksandr


    This book offers broad, detailed coverage of theoretical developments in induction and direct resistance heating and presents new material on the solution of problems in the application of such heating. The physical basis of induction and conduction heating processes is explained, and electromagnetic phenomena in direct resistance and induction heating of flat workpieces and cylindrical bodies are examined in depth. The calculation of electrical and energetic characteristics of induction and conduction heating systems is then thoroughly reviewed. The final two chapters consider analytical solutions and numerical modeling of problems in the application of induction and direct resistance heating, providing industrial engineers with the knowledge needed in order to use numerical tools in the modern design of installations. Other engineers, scientists, and technologists will find the book to be an invaluable reference that will assist in the efficient utilization of electrical energy.

  4. 75 FR 79952 - Airworthiness Directives; DASSAULT AVIATION Model Falcon 10 Airplanes; Model FAN JET FALCON, FAN... (United States)


    ... Airworthiness Directives; DASSAULT AVIATION Model Falcon 10 Airplanes; Model FAN JET FALCON, FAN JET FALCON.... (1) DASSAULT AVIATION Model Falcon 10 airplanes, Model FAN JET FALCON, FAN JET FALCON SERIES C, D, E... airplanes Inspection threshold (whichever occurs later) Inspection interval Model FAN JET FALCON, FAN JET...

  5. Comparison of marine dispersion model predictions with environmental radionuclide concentrations

    International Nuclear Information System (INIS)

    Johnson, C.E.; McKay, W.A.


    The comparison of marine dispersion model results with measurements is an essential part of model development and testing. The results from two residual flow models are compared with seawater concentrations, and in one case with concentrations measured in marine molluscs. For areas with short turnover times, seawater concentrations respond rapidly to variations in discharge rate and marine currents. These variations are difficult to model, and comparison with concentrations in marine animals provides an alternative and complementary technique for model validation with the advantages that the measurements reflect the mean conditions and frequently form a useful time series. (author)

  6. Tip studies using CFD and comparison with tip loss models

    DEFF Research Database (Denmark)

    Hansen, Martin Otto Laver; Johansen, J.


    The flow past a rotating LM8.2 blade equipped with two different tips are computed using CFD. The different tip flows are analysed and a comparison with two different tip loss models is made. Keywords: tip flow, aerodynamics, CFD......The flow past a rotating LM8.2 blade equipped with two different tips are computed using CFD. The different tip flows are analysed and a comparison with two different tip loss models is made. Keywords: tip flow, aerodynamics, CFD...

  7. Analytic solution of a five-direction radiation transport model

    International Nuclear Information System (INIS)

    Cramer, S.N.


    In order to test certain spatial and angular dependent Monte Carlo biasing techniques, a one-dimensional, one energy, two-media, five-direction radiation transport model has been devised for which an analytic solution exists. Although this solution is too long to be conveniently expressed in an explicit form, it can be easily evaluated on the smallest of computers. This solution is discussed in this paper. 1 ref

  8. Information Modeling for Direct Control of Distributed Energy Resources

    DEFF Research Database (Denmark)

    Biegel, Benjamin; Andersen, Palle; Stoustrup, Jakob


    We present an architecture for an unbundled liberalized electricity market system where a virtual power plant (VPP) is able to control a number of distributed energy resources (DERs) directly through a two-way communication link. The aggregator who operates the VPP utilizes the accumulated...... for a whole range of different DERs. The devised information model can serve as input to the international standardization efforts on distributed energy resources....

  9. Modeling water transport in liquid feed direct methanol fuel cells (United States)

    Liu, Wenpeng; Wang, Chao-Yang

    Proper water management in direct methanol fuel cells (DMFCs) is very critical and complicated because of many interacting physicochemical phenomena. Among these, the liquid saturation in the cathode side is believed to have a very strong effect on water crossover through the membrane, a key parameter to determine water balance between the anode and cathode. In this paper, based on an interfacial liquid coverage model implemented in a three-dimensional (3D) two-phase DMFC model, the liquid saturation variations in the cathode are examined in detail and their effects on the net water transport coefficient through the membrane discussed.

  10. Molecular level in silico studies for oncology. Direct models review (United States)

    Psakhie, S. G.; Tsukanov, A. A.


    The combination of therapy and diagnostics in one process "theranostics" is a trend in a modern medicine, especially in oncology. Such an approach requires development and usage of multifunctional hybrid nanoparticles with a hierarchical structure. Numerical methods and mathematical models play a significant role in the design of the hierarchical nanoparticles and allow looking inside the nanoscale mechanisms of agent-cell interactions. The current position of in silico approach in biomedicine and oncology is discussed. The review of the molecular level in silico studies in oncology, which are using the direct models, is presented.

  11. Models of direct reactions and quantum pre-equilibrium for nucleon scattering on spherical nuclei

    International Nuclear Information System (INIS)

    Dupuis, M.


    When a nucleon collides with a target nucleus, several reactions may occur: elastic and inelastic scatterings, charge exchange... In order to describe these reactions, different models are involved: the direct reactions, pre-equilibrium and compound nucleus models. Our goal is to study, within a quantum framework and without any adjustable parameter, the direct and pre-equilibrium reactions for nucleons scatterings off double closed-shell nuclei. We first consider direct reactions: we are studying nucleon scattering with the Melbourne G-matrix, which represents the interaction between the projectile and one target nucleon, and with random phase approximation (RPA) wave functions which describe all target states. This is a fully microscopic approach since no adjustable parameters are involved. A second part is dedicated to the study of nucleon inelastic scattering for large energy transfer which necessarily involves the pre-equilibrium mechanism. Several models have been developed in the past to deal with pre-equilibrium. They start from the Born expansion of the transition amplitude which is associated to the inelastic process and they use several approximations which have not yet been tested. We have achieved some comparisons between second order cross sections which have been calculated with and without these approximations. Our results allow us to criticize some of these approximations and give several directions to improve the quantum pre-equilibrium models. (author)

  12. Directed Diffusion Modelling for Tesso Nilo National Parks Case Study (United States)

    Yasri, Indra; Safrianti, Ery


    Directed Diffusion (DD has ability to achieve energy efficiency in Wireless Sensor Network (WSN). This paper proposes Directed Diffusion (DD) modelling for Tesso Nilo National Parks (TNNP) case study. There are 4 stages of scenarios involved in this modelling. It’s started by appointing of sampling area through GPS coordinate. The sampling area is determined by optimization processes from 500m x 500m up to 1000m x 1000m with 100m increment in between. The next stage is sensor node placement. Sensor node is distributed in sampling area with three different quantities i.e. 20 nodes, 30 nodes and 40 nodes. One of those quantities is choose as an optimized sensor node placement. The third stage is to implement all scenarios in stages 1 and stages 2 on DD modelling. In the last stage, the evaluation process to achieve most energy efficient in the combination of optimized sampling area and optimized sensor node placement on Direct Diffusion (DD) routing protocol. The result shows combination between sampling area 500m x 500m and 20 nodes able to achieve energy efficient to support a forest preventive fire system at Tesso Nilo National Parks.

  13. Thermal Modeling of Direct Digital Melt-Deposition Processes (United States)

    Cooper, K. P.; Lambrakos, S. G.


    Additive manufacturing involves creating three-dimensional (3D) objects by depositing materials layer-by-layer. The freeform nature of the method permits the production of components with complex geometry. Deposition processes provide one more capability, which is the addition of multiple materials in a discrete manner to create "heterogeneous" objects with locally controlled composition and microstructure. The result is direct digital manufacturing (DDM) by which dissimilar materials are added voxel-by-voxel (a voxel is volumetric pixel) following a predetermined tool-path. A typical example is functionally gradient material such as a gear with a tough core and a wear-resistant surface. The inherent complexity of DDM processes is such that process modeling based on direct physics-based theory is difficult, especially due to a lack of temperature-dependent thermophysical properties and particularly when dealing with melt-deposition processes. In order to overcome this difficulty, an inverse problem approach is proposed for the development of thermal models that can represent multi-material, direct digital melt deposition. This approach is based on the construction of a numerical-algorithmic framework for modeling anisotropic diffusivity such as that which would occur during energy deposition within a heterogeneous workpiece. This framework consists of path-weighted integral formulations of heat diffusion according to spatial variations in material composition and requires consideration of parameter sensitivity issues.

  14. A simple model of low-scale direct gauge mediation

    International Nuclear Information System (INIS)

    Csaki, Csaba; Shirman, Yuri; Terning, John


    We construct a calculable model of low-energy direct gauge mediation making use of the metastable supersymmetry breaking vacua recently discovered by Intriligator, Seiberg and Shih. The standard model gauge group is a subgroup of the global symmetries of the SUSY breaking sector and messengers play an essential role in dynamical SUSY breaking: they are composites of a confining gauge theory, and the holomorphic scalar messenger mass appears as a consequence of the confining dynamics. The SUSY breaking scale is around 100 TeV nevertheless the model is calculable. The minimal non-renormalizable coupling of the Higgs to the DSB sector leads in a simple way to a μ-term, while the B-term arises at two-loop order resulting in a moderately large tan β. A novel feature of this class of models is that some particles from the dynamical SUSY breaking sector may be accessible at the LHC

  15. Comparison of direct immunofluorescence and direct immunoperoxidase procedures for detection of herpes simplex virus antigen in lesion specimens.


    Schmidt, N J; Dennis, J; Devlin, V; Gallo, D; Mills, J


    Direct immunofluorescence and direct immunoperoxidase staining were equally sensitive and specific for detection of herpes simplex virus antigen in lesion specimens, and each method showed 82% agreement with virus isolation results.

  16. Some results regarding the comparison of the Earth's atmospheric models

    Directory of Open Access Journals (Sweden)

    Šegan S.


    Full Text Available In this paper we examine air densities derived from our realization of aeronomic atmosphere models based on accelerometer measurements from satellites in a low Earth's orbit (LEO. Using the adapted algorithms we derive comparison parameters. The first results concerning the adjustment of the aeronomic models to the total-density model are given.

  17. Modeling directional thermal radiance from a forest canopy

    International Nuclear Information System (INIS)

    McGuire, M.J.; Balick, L.K.; Smith, J.A.; Hutchison, B.A.


    Recent advances in remote sensing technology have increased interest in utilizing the thermal-infared region to gain additional information about surface features such as vegetation canopies. Studies have shown that sensor view angle, canopy structure, and percentage of canopy coverage can affect the response of a thermal sensor. These studies have been primarily of agricultural regions and there have been relatively few examples describing the thermal characteristics of forested regions. This paper describes an extension of an existing thermal vegetation canopy radiance model which has been modified to partially account for the geometrically rough structure of a forest canopy. Fourier series expansion of a canopy height profile is used to calculate improved view factors which partially account for the directional variations in canopy thermal radiance transfers. The original and updated radiance model predictions are compared with experimental data obtained over a deciduous (oak-hickory) forest site. The experimental observations are also used to document azimuthal and nadir directional radiance variations. Maximum angular variations in measured canopy temperatures were 4–6°C (azimuth) and 2.5°C (nadir). Maximum angular variations in simulated temperatures using the modified rough surface model was 4°C. The rough surface model appeared to be sensitive to large gaps in the canopy height profile, which influenced the resultant predicted temperature. (author)

  18. A comparison of models for risk assessment

    International Nuclear Information System (INIS)

    Kellerer, A.M.; Jing Chen


    Various mathematical models have been used to represent the dependence of excess cancer risk on dose, age and time since exposure. For solid cancers, i.e. all cancers except leukaemia, the so-called relative risk model is usually employed. However, there can be quite different relative risk models. The most usual model for the quantification of excess tumour rate among the atomic bomb survivors has been a dependence of the relative risk on age at exposure, but it has been shown recently that an age attained model can be equally applied, to represent the observations among the atomic bomb survivors. The differences between the models and their implications are explained. It is also shown that the age attained model is similar to the approaches that have been used in the analysis of lung cancer incidence among radon exposed miners. A more unified approach to modelling of radiation risks can thus be achieved. (3 figs.)

  19. Models for the directed evolution of bacterial allelopathy: bacteriophage lysins

    Directory of Open Access Journals (Sweden)

    James J. Bull


    Full Text Available Microbes produce a variety of compounds that are used to kill or suppress other species. Traditional antibiotics have their origins in these natural products, as do many types of compounds being pursued today in the quest for new antibacterial drugs. When a potential toxin can be encoded by and exported from a species that is not harmed, the opportunity exists to use directed evolution to improve the toxin’s ability to kill other species—allelopathy. In contrast to the typical application of directed evolution, this case requires the co-culture of at least two species or strains, a host that is unharmed by the toxin plus the intended target of the toxin. We develop mathematical and computational models of this directed evolution process. Two contexts are considered, one with the toxin encoded on a plasmid and the other with the toxin encoded in a phage. The plasmid system appears to be more promising than the phage system. Crucial to both designs is the ability to co-culture two species/strains (host and target such that the host is greatly outgrown by the target species except when the target species is killed. The results suggest that, if these initial conditions can be satisfied, directed evolution is feasible for the plasmid-based system. Screening with a plasmid-based system may also enable rapid improvement of a toxin.

  20. Modeling Uncertainty of Directed Movement via Markov Chains

    Directory of Open Access Journals (Sweden)

    YIN Zhangcai


    Full Text Available Probabilistic time geography (PTG is suggested as an extension of (classical time geography, in order to present the uncertainty of an agent located at the accessible position by probability. This may provide a quantitative basis for most likely finding an agent at a location. In recent years, PTG based on normal distribution or Brown bridge has been proposed, its variance, however, is irrelevant with the agent's speed or divergent with the increase of the speed; so they are difficult to take into account application pertinence and stability. In this paper, a new method is proposed to model PTG based on Markov chain. Firstly, a bidirectional conditions Markov chain is modeled, the limit of which, when the moving speed is large enough, can be regarded as the Brown bridge, thus has the characteristics of digital stability. Then, the directed movement is mapped to Markov chains. The essential part is to build step length, the state space and transfer matrix of Markov chain according to the space and time position of directional movement, movement speed information, to make sure the Markov chain related to the movement speed. Finally, calculating continuously the probability distribution of the directed movement at any time by the Markov chains, it can be get the possibility of an agent located at the accessible position. Experimental results show that, the variance based on Markov chains not only is related to speed, but also is tending towards stability with increasing the agent's maximum speed.

  1. Differential Binding Models for Direct and Reverse Isothermal Titration Calorimetry. (United States)

    Herrera, Isaac; Winnik, Mitchell A


    Isothermal titration calorimetry (ITC) is a technique to measure the stoichiometry and thermodynamics from binding experiments. Identifying an appropriate mathematical model to evaluate titration curves of receptors with multiple sites is challenging, particularly when the stoichiometry or binding mechanism is not available. In a recent theoretical study, we presented a differential binding model (DBM) to study calorimetry titrations independently of the interaction among the binding sites (Herrera, I.; Winnik, M. A. J. Phys. Chem. B 2013, 117, 8659-8672). Here, we build upon our DBM and show its practical application to evaluate calorimetry titrations of receptors with multiple sites independently of the titration direction. Specifically, we present a set of ordinary differential equations (ODEs) with the general form d[S]/dV that can be integrated numerically to calculate the equilibrium concentrations of free and bound species S at every injection step and, subsequently, to evaluate the volume-normalized heat signal (δQ(V) = δq/dV) of direct and reverse calorimetry titrations. Additionally, we identify factors that influence the shape of the titration curve and can be used to optimize the initial concentrations of titrant and analyte. We demonstrate the flexibility of our updated DBM by applying these differentials and a global regression analysis to direct and reverse calorimetric titrations of gadolinium ions with multidentate ligands of increasing denticity, namely, diglycolic acid (DGA), citric acid (CIT), and nitrilotriacetic acid (NTA), and use statistical tests to validate the stoichiometries for the metal-ligand pairs studied.

  2. Modulating and evaluating receptor promiscuity through directed evolution and modeling. (United States)

    Stainbrook, Sarah C; Yu, Jessica S; Reddick, Michael P; Bagheri, Neda; Tyo, Keith E J


    The promiscuity of G-protein-coupled receptors (GPCRs) has broad implications in disease, pharmacology and biosensing. Promiscuity is a particularly crucial consideration for protein engineering, where the ability to modulate and model promiscuity is essential for developing desirable proteins. Here, we present methodologies for (i) modifying GPCR promiscuity using directed evolution and (ii) predicting receptor response and identifying important peptide features using quantitative structure-activity relationship models and grouping-exhaustive feature selection. We apply these methodologies to the yeast pheromone receptor Ste2 and its native ligand α-factor. Using directed evolution, we created Ste2 mutants with altered specificity toward a library of α-factor variants. We then used the  Vectors of Hydrophobic, Steric, and Electronic properties and partial least squares regression to characterize receptor-ligand interactions, identify important ligand positions and properties, and predict receptor response to novel ligands. Together, directed evolution and computational analysis enable the control and evaluation of GPCR promiscuity. These approaches should be broadly useful for the study and engineering of GPCRs and other protein-small molecule interactions. © The Author 2017. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail:

  3. Allosteric transition: a comparison of two models

    DEFF Research Database (Denmark)

    Bindslev, Niels


    Introduction Two recent models are in use for analysis of allosteric drug action at receptor sites remote from orthosteric binding sites. One is an allosteric two-state mechanical model derived in 2000 by David Hall. The other is an extended operational model developed in 2007 by Arthur Christopo...

  4. Regulatory ozone modeling: status, directions, and research needs. (United States)

    Georgopoulos, P G


    ) the improvement of the model-based ozone-attainment demonstration process are presented to identify future directions in this area.

  5. Comparison of video and direct observation methods for measuring oral behaviour in veal calves

    Directory of Open Access Journals (Sweden)

    Marina Verga


    Full Text Available Measuring behaviour, especially oral behaviour, has always been a debated issue: therefore the aim of this paper is to closely examine the study of oral behaviour in calves and the approaching methodology. Behavioural observations were conducted by two media (direct observations by check sheets and indirect observations by videotapes recorded by cam- eras connected to a digital field switcher and a time-lapse video recorder in order to compare data and assess the reli- ability and validity of the two methods in identifying some oral behavioural patterns in calves. The study was carried out on 54 Polish Friesian calves housed in group pens and in individual crates. The behaviour of the calves was investigated during the fattening period on the 2nd, 7th, 13th, 18th and 23rd week, one hour before and one hour after each of the two meals. Two experienced observers checked the behaviour of the calves, including oral behaviours on structures and buckets and oral stereotypies, by direct observations using a scan sampling every 2 min- utes. The calves' behaviour was also video recorded on the same days in which the direct observations were carried out and analysed by the same two observers. Percentages of time spent on each type of behaviour were calculated and anal- ysed by Chi-square test. Regardless of the housing system, the comparison between direct and indirect observations revealed significant differences in almost every behavioural category. Licking, biting and nibbling structures, nibbling and sucking the bucket, playing with the bucket and the teat, chewing and oral stereotypies were significantly higher in direct observations compared to indirect (P < 0.001, while inactivity was higher in video recorded observations (P < 0.001. In conclusion, regardless of the type of housing, our results revealed an objective difficulty in analysing videotapes with very detailed behavioural categories, like oral behaviours. Although video recording can

  6. Direct comparison of unloading compliance and potential drop techniques in J-integral testing

    Energy Technology Data Exchange (ETDEWEB)

    McGowan, J.J.; Nanstad, R.K.


    Single-specimen J-integral testing is performed commonly with the unloading compliance technique. Use of modern instrumentation techniques and powerful desktop computers have made this technique a standard. However, this testing technique is slow and tedious, with the loading rate fixed at a slow quasi-static rate. For these reasons the dc potential drop technique was investigated for crack length measurement during a J-integral test. For direct comparison, both unloading compliance and potential drop were used simultaneously during a J-integral test. The results showed good agreement between the techniques. However, the potential drop technique showed an offset in crack length due to plastic blunting processes. Taking this offset into account, J/sub Ic/ values calculated by both techniques compared well.

  7. Direct comparison of soft x-ray images of organelles with optical fluorescence images

    International Nuclear Information System (INIS)

    Ishino, Masahiko; Kado, Masataka; Kishimoto, Maki; Nishikino, Masaharu; Ohba, Toshiyuki; Kaihori, Takeshi; Kawachi, Tetsuya; Tamotsu, Satoshi; Yasuda, Keiko; Mikata, Yuji; Shinohara, Kunio


    Soft x-ray microscopes operating in the water window region are capable of imaging living hydrated cells. Up to now, we have been able to take some soft x-ray images of living cells by the use of a contact x-ray microscope system with laser produced plasma soft x-ray source. Since the soft x-ray images are different from the optical images obtained with an ordinary microscope, it is very important to identify what is seen in the x-ray images. Hence, we have demonstrated the direct comparison between the images of organelles obtained with a fluorescence microscope and those with a soft x-ray microscope. Comparing the soft x-ray images to the fluorescence images, the fine structures of the organelles could be identified and observed. (author)

  8. Direct comparisons of treatment modalities for youth disorders: a meta-analysis. (United States)

    Miller, Scott; Wampold, Bruce; Varhely, Katelyn


    A meta-analysis was conducted to determine whether differences in efficacy exist among treatment approaches applied to youth. Included were all studies published between 1980 and 2005 involving participants 18 years of age or younger with diagnoses of depression, anxiety, conduct disorder, and attention-deficit/hyperactivity disorder that contained direct comparisons among two or more treatment methods intended to be therapeutic. Effect sizes were found to vary significantly, providing some evidence that differences in efficacy exist among treatments for these disorders in youth. However, the upper bound of the true difference in effects among treatments was small. Furthermore, researcher allegiance was found to be strongly associated with the difference in effect sizes so that when allegiance was controlled there was no evidence of any differences among treatments.

  9. Comparison of Transcription Factor Binding Site Models

    KAUST Repository

    Bhuyan, Sharifulislam


    Modeling of transcription factor binding sites (TFBSs) and TFBS prediction on genomic sequences are important steps to elucidate transcription regulatory mechanism. Dependency of transcription regulation on a great number of factors such as chemical specificity, molecular structure, genomic and epigenetic characteristics, long distance interaction, makes this a challenging problem. Different experimental procedures generate evidence that DNA-binding domains of transcription factors show considerable DNA sequence specificity. Probabilistic modeling of TFBSs has been moderately successful in identifying patterns from a family of sequences. In this study, we compare performances of different probabilistic models and try to estimate their efficacy over experimental TFBSs data. We build a pipeline to calculate sensitivity and specificity from aligned TFBS sequences for several probabilistic models, such as Markov chains, hidden Markov models, Bayesian networks. Our work, containing relevant statistics and evaluation for the models, can help researchers to choose the most appropriate model for the problem at hand.

  10. Modelling 1-minute directional observations of the global irradiance. (United States)

    Thejll, Peter; Pagh Nielsen, Kristian; Andersen, Elsa; Furbo, Simon


    Direct and diffuse irradiances from the sky has been collected at 1-minute intervals for about a year from the experimental station at the Technical University of Denmark for the IEA project "Solar Resource Assessment and Forecasting". These data were gathered by pyrheliometers tracking the Sun, as well as with apertured pyranometers gathering 1/8th and 1/16th of the light from the sky in 45 degree azimuthal ranges pointed around the compass. The data are gathered in order to develop detailed models of the potentially available solar energy and its variations at high temporal resolution in order to gain a more detailed understanding of the solar resource. This is important for a better understanding of the sub-grid scale cloud variation that cannot be resolved with climate and weather models. It is also important for optimizing the operation of active solar energy systems such as photovoltaic plants and thermal solar collector arrays, and for passive solar energy and lighting to buildings. We present regression-based modelling of the observed data, and focus, here, on the statistical properties of the model fits. Using models based on the one hand on what is found in the literature and on physical expectations, and on the other hand on purely statistical models, we find solutions that can explain up to 90% of the variance in global radiation. The models leaning on physical insights include terms for the direct solar radiation, a term for the circum-solar radiation, a diffuse term and a term for the horizon brightening/darkening. The purely statistical model is found using data- and formula-validation approaches picking model expressions from a general catalogue of possible formulae. The method allows nesting of expressions, and the results found are dependent on and heavily constrained by the cross-validation carried out on statistically independent testing and training data-sets. Slightly better fits -- in terms of variance explained -- is found using the purely

  11. Comparison of global and regional ionospheric models (United States)

    Ranner, H.-P.; Krauss, S.; Stangl, G.


    Modelling of the Earth's ionosphere means the description of the variability of the vertical TEC (Total Electron Content) in dependence of geographic latitude and longitude, height, diurnal and seasonal variation as well as solar activity. Within the project GIOMO (next Generation near real-time IOnospheric MOdels) the objectives are the identification and consolidation of improved ionospheric modelling technologies. The global models Klobuchar (GPS) and NeQuick (currently in use by EGNOS, in future used by Galileo) are compared to the IGS (International GNSS Service) Final GIM (Global Ionospheric Map). Additionally a RIM (Regional Ionospheric Map) for Europe provided by CODE (Center for Orbit Determination in Europe) is investigated. Furthermore the OLG (Observatorium Lustbühel Graz) regional models are calculated for two test beds with different latitudes and extensions (Western Austria and the Aegean region). There are three different approaches, two RIMs are based on spherical harmonics calculated either from code or phase measurements and one RIM is based on a Taylor series expansion around a central point estimated from zero-difference observations. The benefits of regional models are the local flexibility using a dense network of GNSS stations. Near real-time parameters are provided within ten minutes after every clock hour. All models have been compared according to their general behavior, the ability to react upon extreme solar events and the robustness of estimation. A ranking of the different models showed a preference for the RIMs while the global models should be used within a fall-back strategy.

  12. A model for the evolution of nucleotide polymerase directionality.

    Directory of Open Access Journals (Sweden)

    Joshua Ballanco

    Full Text Available BACKGROUND: In all known living organisms, every enzyme that synthesizes nucleic acid polymers does so by adding nucleotide 5′-triphosphates to the 3′-hydroxyl group of the growing chain. This results in the well known 5'→3' directionality of all DNA and RNA Polymerases. The lack of any alternative mechanism, e.g. addition in a 3'→5' direction, may indicate a very early founder effect in the evolution of life, or it may be the result of a selective pressure against such an alternative. METHODOLOGY/PRINCIPAL FINDINGS: In an attempt to determine whether the lack of an alternative polymerase directionality is the result of a founder effect or evolutionary selection, we have constructed a basic model of early polymerase evolution. This model is informed by the essential chemical properties of the nucleotide polymerization reaction. With this model, we are able to simulate the growth of organisms with polymerases that synthesize either 5'→3' or 3'→5' in isolation or in competition with each other. CONCLUSIONS/SIGNIFICANCE: We have found that a competition between organisms with 5'→3' polymerases and 3'→5' polymerases only results in a evolutionarily stable strategy under certain conditions. Furthermore, we have found that mutations lead to a much clearer delineation between conditions that lead to a stable coexistence of these populations and conditions which ultimately lead to success for the 5'→3' form. In addition to presenting a plausible explanation for the uniqueness of enzymatic polymerization reactions, we hope these results also provide an example of how whole organism evolution can be understood based on molecular details.

  13. Data Analysis A Model Comparison Approach, Second Edition

    CERN Document Server

    Judd, Charles M; Ryan, Carey S


    This completely rewritten classic text features many new examples, insights and topics including mediational, categorical, and multilevel models. Substantially reorganized, this edition provides a briefer, more streamlined examination of data analysis. Noted for its model-comparison approach and unified framework based on the general linear model, the book provides readers with a greater understanding of a variety of statistical procedures. This consistent framework, including consistent vocabulary and notation, is used throughout to develop fewer but more powerful model building techniques. T

  14. Direct burial and vault emplacement data quality comparison at Dotson Ranch, New Mexico (United States)

    Beaudoin, B. C.; Aderhold, K.; Anderson, K.; Pfeifer, M.; Parker, T.; Miller, P. E.; Slad, G. W.; Reusch, A.


    We compare the data quality of two emplacement methods for portable broadband seismic stations, traditional vault and direct burial, using power spectral density analysis to examine temporal trends in noise, the ratio of signal-to-noise for local, regional and teleseismic earthquakes, coherence of both noise and earthquake signal recordings as well as overall data return. Sensor emplacement in the past has been overwhelmingly dominated by traditional vaults requiring more materials, manpower and time. A new technique of directly burying sensors drastically reduces the expense, personnel and time required to install a seismic station. Comparisons between the data quality of vault and direct buried sensors are needed to show that the time and money saved in emplacement does not downgrade the quality of the data collected. Two identical shallow vaults were installed adjacent to two identical direct burial sites at Dotson Ranch in San Antonio, New Mexico, in a deliberately-chosen noisy, wet and generally inhospitable location. These four sites each used a Guralp 3T sensor retrofitted with a waterproof lid and connector. Eight months of data recorded during 2012 from these four sensors are compared in order to determine if the emplacement method has a profound and systematic effect on data quality using several different metrics that mimic the actual use of seismic data in research. A posthole installation with a Nanometrics Trillium 120PH sensor was also installed at the site for a portion of the study and six months of data are included in the analysis. Overall the variability in data quality metrics used in this study is comparable between sites with differing emplacement method as it is between sites with the same emplacement method. Noise in the vaults is higher in amplitude during the transition from spring to summer as compared to the direct burials and is especially evident on the horizontal components at long periods between 20-170 seconds. Diurnal changes in

  15. Markov chain Monte Carlo methods in directed graphical models

    DEFF Research Database (Denmark)

    Højbjerre, Malene

    have primarily been based on a Bayesian paradigm, i.e. prior information on the parameters is a prerequisite, but questions about undesirable side effects from the priors are raised.     We present a method, based on MCMC methods, that approximates profile log-likelihood functions in directed graphical...... a tendency to foetal loss is heritable. The data possess a complicated dependence structure due to replicate pregnancies for the same woman, and a given family pattern. We conclude that a tendency to foetal loss is heritable. The model is of great interest in genetic epidemiology, because it considers both...

  16. Inter-comparison of different direct and indirect methods to determine radon flux from soil

    International Nuclear Information System (INIS)

    Grossi, C.; Vargas, A.; Camacho, A.; Lopez-Coto, I.; Bolivar, J.P.; Xia Yu; Conen, F.


    The physical and chemical characteristics of radon gas make it a good tracer for use in the application of atmospheric transport models. For this purpose the radon source needs to be known on a global scale and this is difficult to achieve by only direct experimental methods. However, indirect methods can provide radon flux maps on larger scales, but their reliability has to be carefully checked. It is the aim of this work to compare radon flux values obtained by direct and indirect methods in a measurement campaign performed in the summer of 2008. Different systems to directly measure radon flux from the soil surface and to measure the related parameters terrestrial γ dose and 226 Ra activity in soil, for indirect estimation of radon flux, were tested. Four eastern Spanish sites with different geological and soil characteristics were selected: Teruel, Los Pedrones, Quintanar de la Orden and Madrid. The study shows the usefulness of both direct and indirect methods for obtaining radon flux data. Direct radon flux measurements by continuous and integrated monitors showed a coefficient of variation between 10% and 23%. At the same time, indirect methods based on correlations between 222 Rn and terrestrial γ dose rate, or 226 Ra activity in soil, provided results similar to the direct measurements, when these proxies were directly measured at the site. Larger discrepancies were found when proxy values were extracted from existing data bases. The participating members involved in the campaign study were the Institute of Energy Technology (INTE) of the Technical University of Catalonia (UPC), Huelva University (UHU), and Basel University (BASEL).

  17. Inter-comparison of different direct and indirect methods to determine radon flux from soil

    Energy Technology Data Exchange (ETDEWEB)

    Grossi, C., E-mail: claudia.grossi@upc.ed [Institute of Energy (INTE), Technical University of Catalonia (UPC) (Spain); Vargas, A.; Camacho, A. [Institute of Energy (INTE), Technical University of Catalonia (UPC) (Spain); Lopez-Coto, I.; Bolivar, J.P. [University of Huelva (Spain); Xia Yu; Conen, F. [University of Basel (Switzerland)


    The physical and chemical characteristics of radon gas make it a good tracer for use in the application of atmospheric transport models. For this purpose the radon source needs to be known on a global scale and this is difficult to achieve by only direct experimental methods. However, indirect methods can provide radon flux maps on larger scales, but their reliability has to be carefully checked. It is the aim of this work to compare radon flux values obtained by direct and indirect methods in a measurement campaign performed in the summer of 2008. Different systems to directly measure radon flux from the soil surface and to measure the related parameters terrestrial {gamma} dose and {sup 226}Ra activity in soil, for indirect estimation of radon flux, were tested. Four eastern Spanish sites with different geological and soil characteristics were selected: Teruel, Los Pedrones, Quintanar de la Orden and Madrid. The study shows the usefulness of both direct and indirect methods for obtaining radon flux data. Direct radon flux measurements by continuous and integrated monitors showed a coefficient of variation between 10% and 23%. At the same time, indirect methods based on correlations between {sup 222}Rn and terrestrial {gamma} dose rate, or {sup 226}Ra activity in soil, provided results similar to the direct measurements, when these proxies were directly measured at the site. Larger discrepancies were found when proxy values were extracted from existing data bases. The participating members involved in the campaign study were the Institute of Energy Technology (INTE) of the Technical University of Catalonia (UPC), Huelva University (UHU), and Basel University (BASEL).

  18. A forecast comparison of volatility models

    DEFF Research Database (Denmark)

    Hansen, Peter Reinhard; Lunde, Asger


    We compare 330 ARCH-type models in terms of their ability to describe the conditional variance. The models are compared out-of-sample using DM-$ exchange rate data and IBM return data, where the latter is based on a new data set of realized variance. We find no evidence that a GARCH(1,1) is outpe...

  19. Amorphous track models: A numerical comparison study

    DEFF Research Database (Denmark)

    Greilich, Steffen; Grzanka, L.; Bassler, N.


    We present an open-source code library for amorphous track modelling which is suppose to faciliate the application and numerical comparability as well as serve as a frame-work for the implementation of new models. We show an example of using the library indicating the choice of submodels has a si...

  20. Comparison of two different modelling tools

    DEFF Research Database (Denmark)

    Brix, Wiebke; Elmegaard, Brian


    In this paper a test case is solved using two different modelling tools, Engineering Equation Solver (EES) and WinDali, in order to compare the tools. The system of equations solved, is a static model of an evaporator used for refrigeration. The evaporator consists of two parallel channels, and i...

  1. Dynamic energy-demand models. A comparison

    International Nuclear Information System (INIS)

    Yi, Feng


    This paper compares two second-generation dynamic energy demand models, a translog (TL) and a general Leontief (GL), in the study of price elasticities and factor substitutions of nine Swedish manufacturing industries: food, textiles, wood, paper, printing, chemicals, non-metallic minerals, base metals and machinery. Several model specifications are tested with likelihood ratio test. There is a disagreement on short-run adjustments; the TL model accepts putty-putty production technology of immediate adjustments, implying equal short- and long-run price elasticities of factors, while the GL model rejects immediate adjustments, giving out short-run elasticities quite different from the long-run. The two models also disagree in substitutability in many cases. 21 refs

  2. A physical model of Direct Methanol Fuel Cell anode impedance (United States)

    Zago, M.; Casalegno, A.


    In the present work a physically based model of direct methanol fuel cell anode impedance has been developed and validated at different operating current densities. The proposed model includes the two-phase mass transport of both methanol and water through diffusion and catalyst layers and the methanol oxidation reaction involving CO adsorbed intermediate. Model simulations are in good quantitative agreement with experimental observations and permit to evaluate the origin of anode impedance features. Model results confirm that the high frequency 45° linear branch is caused by proton transport limitations within the catalyst layer and that the low frequency inductive behavior is due to surface coverage by CO reaction intermediate. Moreover model predictions elucidate the contribution to the impedance of mass transport phenomena through diffusion layer, that is relevant even at low current density and increases along the channel length. In particular liquid convective fluxes are considered as a process of pressure buildup and breakthrough at diffusion layer intersecting fibers, resulting in a discontinuous phenomenon. By means of this intermittent description it is possible to correctly reproduce mass transport limitations through diffusion layers, that manifest themselves as a second arch superimposed to the first one, peculiar of kinetic losses.

  3. 3D flame topography obtained by tomographic chemiluminescence with direct comparison to planar Mie scattering measurements. (United States)

    Xu, Wenjiang; Wickersham, A J; Wu, Yue; He, Fan; Ma, Lin


    This work reports the measurements of 3D flame topography using tomographic chemiluminescence and its validation by direct comparison against planar Mie scattering measurements. Tomographic measurements of the 3D topography of various well-controlled laboratory flames were performed using projections measured by seven cameras, and a simultaneous Mie scattering measurement was performed to measure a 2D cross section of the 3D flame topography. The tomographic measurements were based on chemiluminescence emissions from the flame, and the Mie scattering measurements were based on micrometer-size oil droplets seeded into the flow. The flame topography derived from the 3D tomographic and the Mie scattering measurement was then directly compared. The results show that the flame topography obtained from tomographic chemiluminescence and the Mie measurement agreed qualitatively (i.e., both methods yielded the same profile of the flame fronts), but a quantitative difference on the order of millimeters was observed between these two methods. These results are expected to be useful for understanding the capabilities and limitations of the 3D tomographic and Mie scattering techniques in combustion diagnostics.

  4. Directionally Solidified Aluminum - 7 wt% Silicon Alloys: Comparison of Earth and International Space Station Processed Samples (United States)

    Grugel, Richard N,; Tewari, Surendra; Rajamure, R. S.; Erdman, Robert; Poirier, David


    Primary dendrite arm spacings of Al-7 wt% Si alloy directionally solidified in low gravity environment of space (MICAST-6 and MICAST-7: Thermal gradient approx. 19 to 26 K/cm, Growth speeds varying from 5 to 50 microns/s show good agreement with the Hunt-Lu model. Primary dendrite trunk diameters of the ISS processed samples show a good fit with a simple analytical model based on Kirkwood s approach, proposed here. Natural convection, a) decreases primary dendrite arm spacing. b) appears to increase primary dendrite trunk diameter.

  5. Comparison of two uranium-market forecasting models

    International Nuclear Information System (INIS)

    Bleistein, S.; Recek, J.


    The techniques and methodologies, similarities and differences, and the results of two uranium market computer models - the Uranium Supply Analysis System and the EUREKA model - are surveyed. These models can be of use to electric utilities in developing procurement strategies or planning new reactor requirements. The models are designed to simulate actual market performance of the domestic uranium industry under varying user-specified assumptions. These models provide output in the form of projections of variables of interest, such as investment in exploration and new production capacity, additions to reserves and resources, and adjustments in inventories. Comparison between the models is demonstrative of how output can vary even with use of the same input data. Utilities may profit by the comparison with respect to the task of selecting models on the basis of obtaining the most-useful solution for a given problem. 18 figures

  6. Direction of Effects in Multiple Linear Regression Models. (United States)

    Wiedermann, Wolfgang; von Eye, Alexander


    Previous studies analyzed asymmetric properties of the Pearson correlation coefficient using higher than second order moments. These asymmetric properties can be used to determine the direction of dependence in a linear regression setting (i.e., establish which of two variables is more likely to be on the outcome side) within the framework of cross-sectional observational data. Extant approaches are restricted to the bivariate regression case. The present contribution extends the direction of dependence methodology to a multiple linear regression setting by analyzing distributional properties of residuals of competing multiple regression models. It is shown that, under certain conditions, the third central moments of estimated regression residuals can be used to decide upon direction of effects. In addition, three different approaches for statistical inference are discussed: a combined D'Agostino normality test, a skewness difference test, and a bootstrap difference test. Type I error and power of the procedures are assessed using Monte Carlo simulations, and an empirical example is provided for illustrative purposes. In the discussion, issues concerning the quality of psychological data, possible extensions of the proposed methods to the fourth central moment of regression residuals, and potential applications are addressed.

  7. Radiation damage of DNA. Model for direct ionization of DNA

    International Nuclear Information System (INIS)

    Kobayashi, Kazuo; Tagawa, Seiichi


    Current aspects of radiation damage of DNA, particularly induced by the direct effect of radiation, and author's method of pulse radiolysis are described in relation to behavior of ions formed by radiation and active principles to induce the strand break. In irradiation of DNA solution in water, the direct effect of radiation is derived from ionization of DNA itself and indirect one, from the reaction between DNA and radicals generated from water molecules and the former direct one has been scarcely investigated due to difficulty of experimental approach. Radicals generated in sugar moiety of DNA are shown important in the strand break by recent studies on crystalline DNA irradiated by X-ray, DNA solution by electron and photon beams, hydrated DNA by γ-ray and by high linear energy transfer (LET) ion. Author's pulse radiolysis studies have revealed behaviors of guanine and adenine radical cations in dynamics of DNA oxidation. Since reactions described are the model, the experimental approach is thought necessary for elucidation of the actually occurring DNA damage in living cells. (N.I.)

  8. Direct search for the standard model Higgs boson

    CERN Document Server

    Janot, Patrick


    For twelve years, LEP revolutionized the knowledge of electroweak symmetry breaking within the standard model, and the direct discovery of the Higgs boson would have been the crowning achievement. Searches at the Z resonance and above the W/sup +/W/sup -/ threshold allowed an unambiguous lower limit on the mass of the standard model Higgs boson to set be at 114.1 GeV.c/sup -2/. After years of efforts to push the LEP performance far beyond the design limits, hints of what could be the first signs of the existence of a 115 GeV-c/sup -2/ Higgs boson appeared in June 2000, were confirmed in September, and were then confirmed again in November. An additional six-month period of LEP operation was enough to provide a definite answer, with an opportunity to make a fundamental discovery of prime importance. (37 refs).

  9. Modeling the distribution of ammonia across Europe including bi-directional surface–atmosphere exchange

    Directory of Open Access Journals (Sweden)

    R. J. Wichink Kruit


    Full Text Available A large shortcoming of current chemistry transport models (CTM for simulating the fate of ammonia in the atmosphere is the lack of a description of the bi-directional surface–atmosphere exchange. In this paper, results of an update of the surface–atmosphere exchange module DEPAC, i.e. DEPosition of Acidifying Compounds, in the chemistry transport model LOTOS-EUROS are discussed. It is shown that with the new description, which includes bi-directional surface–atmosphere exchange, the modeled ammonia concentrations increase almost everywhere, in particular in agricultural source areas. The reason is that by using a compensation point the ammonia lifetime and transport distance is increased. As a consequence, deposition of ammonia and ammonium decreases in agricultural source areas, while it increases in large nature areas and remote regions especially in southern Scandinavia. The inclusion of a compensation point for water reduces the dry deposition over sea and allows reproducing the observed marine background concentrations at coastal locations to a better extent. A comparison with measurements shows that the model results better represent the measured ammonia concentrations. The concentrations in nature areas are slightly overestimated, while the concentrations in agricultural source areas are still underestimated. Although the introduction of the compensation point improves the model performance, the modeling of ammonia remains challenging. Important aspects are emission patterns in space and time as well as a proper approach to deal with the high concentration gradients in relation to model resolution. In short, the inclusion of a bi-directional surface–atmosphere exchange is a significant step forward for modeling ammonia.

  10. Direction of Serbian Trade: Gravity Model Based on Pool Data

    Directory of Open Access Journals (Sweden)

    Vladimir Ristanovic


    Full Text Available The objective of this paper is to evaluate the effects of bilateral trade between Serbia and EU countries in the period 2001-2015 on the basis of a gravity model. So far in research papers the gravity model has been used for the evaluation of effects of trade among different countries. The gravity model, which combines the cross-section data and the time-series data, has been estimated to the panel data. Estimated results based on a sample of 28 countries reveal that the economic size of foreign countries, the market size of trading partners (the number of inhabitants, and the geographical distance produce altogether huge effects on Serbia’s total trade and exports. Border and language factors have also been taken into account. The research leaves room for further scientific analyses and provides guidance for trade policy creators in analyses for directions of the Serbian trade. This research is based on complex econometric analyses and a recognised model, and shows that there is considerable room for the growth of bilateral trade between Serbia and EU.

  11. Direct comparison of low- and mid-frequency Raman spectroscopy for quantitative solid-state pharmaceutical analysis. (United States)

    Lipiäinen, Tiina; Fraser-Miller, Sara J; Gordon, Keith C; Strachan, Clare J


    This study considers the potential of low-frequency (terahertz) Raman spectroscopy in the quantitative analysis of ternary mixtures of solid-state forms. Direct comparison between low-frequency and mid-frequency spectral regions for quantitative analysis of crystal form mixtures, without confounding sampling and instrumental variations, is reported for the first time. Piroxicam was used as a model drug, and the low-frequency spectra of piroxicam forms β, α2 and monohydrate are presented for the first time. These forms show clear spectral differences in both the low- and mid-frequency regions. Both spectral regions provided quantitative models suitable for predicting the mixture compositions using partial least squares regression (PLSR), but the low-frequency data gave better models, based on lower errors of prediction (2.7, 3.1 and 3.2% root-mean-square errors of prediction [RMSEP] values for the β, α2 and monohydrate forms, respectively) than the mid-frequency data (6.3, 5.4 and 4.8%, for the β, α2 and monohydrate forms, respectively). The better performance of low-frequency Raman analysis was attributed to larger spectral differences between the solid-state forms, combined with a higher signal-to-noise ratio. Copyright © 2017 Elsevier B.V. All rights reserved.

  12. Comparison of perceived value structural models

    Directory of Open Access Journals (Sweden)

    Sunčana Piri Rajh


    Full Text Available Perceived value has been considered an important determinant of consumer shopping behavior and studied as such for a long period of time. According to one research stream, perceived value is a variable determined by perceived quality and perceived sacrifice. Another research stream suggests that the perception of value is a result of the consumer risk perception. This implies the presence of two somewhat independent research streams that are integrated by a third research stream – the one suggesting that perceived value is a result of perceived quality and perceived sacrifices while perceived (performance and financial risk mediates the relationship between perceived quality and perceived sacrifices on the one hand, and perceived value on the other. This paper describes the three approaches (models that have been mentioned. The aim of the paper is to determine which of the observed models show the most acceptable level of fit to the empirical data. Using the survey method, research involving three product categories has been conducted on a sample of Croatian consumers. Collected data was analyzed by the structural equation modeling (SEM method. Research has shown an appropriate level of fit of each observed model to the empirical data. However, the model measuring the effect of perceived risk on perceived value indicates the best level of fit, which implies that perceived performance risk and perceived financial risk are the best predictors of perceived value.

  13. Comparison of models discribing cladding deformations during LOCA

    International Nuclear Information System (INIS)

    Chakraborty, A.K.; Zipper, R.


    This report compares the important models for the determination of cladding deformations during LOCA. In addition to the comparisons of underlying assumptions of different models the same is done for the coefficients applied for the models. In order to assess the predictive capability of the models the calculated results are compared with the experimental results of the individual claddings. It was found out that the results of temperature ramp tests could be calculated better than that of the pressure ramp tests. The calculations revealed that even with the simplified assumption of the model used in TESPA the agreement of the calculated results with those of model NORA was relatively good. (orig.) [de

  14. Comparison of Different Mathematical Models of Cavitation

    Directory of Open Access Journals (Sweden)

    Dorota HOMA


    Full Text Available Cavitation occurs during the flow when local pressure drops to the saturation pressure according to the temperature of the flow. It includes both evaporation and condensation of the vapor bubbles, which occur alternately with high frequency. Cavitation can be very dangerous, especially for pumps, because it leads to break of flow continuity, noise, vibration, erosion of blades and change in pump’s characteristics. Therefore it is very important for pump designers and users to avoid working in cavitation conditions. Simulation of flow can be very useful in that and can indicate if there is risk of cavitating flow occurrence. As this is a multiphase flow and quite complicated phenomena, there are a few mathematical models describing it. The aim of this paper is to make a short review of them and describe their approach to model cavitation. It is desirable to know differences between them to model this phenomenon properly.

  15. Comparison of Communication Models for Mobile Agents

    Directory of Open Access Journals (Sweden)

    Xining Li


    Full Text Available An agent is a self-contained process being acting on behalf of a user. A Mobile Agent is an agent roaming the internet to access data and services, and carry out its assigned task remotely. This paper will focus on the communication models for Mobile Agents. Generally speaking, communication models concern with problems of how to name Mobile Agents, how to establish communication relationships, how to trace moving agents, and how to guarantee reliable communication. Some existing MA systems are purely based on RPC-style communication, whereas some adopts asynchronous message passing, or event registration/handling. Different communication concepts suitable for Mobile Agents are well discussed in [1]. However, we will investigate these concepts and existing models from a different point view: how to track down agents and deliver messages in a dynamic, changing world.

  16. BIOMOVS test scenario model comparison using BIOPATH

    International Nuclear Information System (INIS)

    Grogan, H.A.; Van Dorp, F.


    This report presents the results of the irrigation test scenario, presented in the BIOMOVS intercomparison study, calculated by the computer code BIOPATH. This scenario defines a constant release of Tc-99 and Np-237 into groundwater that is used for irrigation. The system of compartments used to model the biosphere is based upon an area in northern Switzerland and is essentially the same as that used in Projekt Gewaehr to assess the radiological impact of a high level waste repository. Two separate irrigation methods are considered, namely ditch and overhead irrigation. Their influence on the resultant activities calculated in the groundwater, soil and different foodproducts, as a function of time, is evaluated. The sensitivity of the model to parameter variations is analysed which allows a deeper understanding of the model chain. These results are assessed subjectively in a first effort to realistically quantify the uncertainty associated with each calculated activity. (author)

  17. Comparisons between direct and inverse approaches in problems of recovering the true profile of a spectral line

    CERN Document Server

    Mijovic, S


    Computer-supported techniques are introduced in the evaluation of experimental data and obtaining the real profile of spectral lines. The direct and inverse approaches were used. The MINUIT program from the packets of CERN's library was used to solve direct problems. Tikhonov's regularization method was also applied to solve the same problems in an inverse manner. Model functions were introduced to check the applicability limitation of these methods and make a comparison between them as well. The advantages and disadvantages of these approaches were shown. The procedures were applied to the measured profiles of He II's spectral lines in a pulsed low-pressure arc. The chosen lines are He II Paschen-alpha (468.6 nm) in the visible region and Balmer-beta (121.5 nm) in the VUV spectral region. The range of experimental errors was determined where both approaches have given reliable results. It was found that we can obtain the real profile of He II 468.6 nm and He II 121.5 nm spectral lines, using the regularizati...

  18. The Use of Direct Solver in Vector Finite Element Modeling for Calculating 3-D Magnetotelluric Responses

    International Nuclear Information System (INIS)

    Prihantoro, Rudy; Sutarno, Doddy; Nurhasan


    In this work, we seek numerical solution of 3-D Magnetotelluric (MT) using edge- based finite element method. This approach is a variant of standard finite element method and commonly referred as vector finite-element (VFE) method. Nonphysical solutions usually occurred when the solution is sought using standard finite element which is a node based element. Vector finite element attempt to overcome those nonphysical solutions by using the edges of the element as vector basis. The proposed approach on solving second order Maxwell differential equation of 3-D MT is using direct solver rather than iterative method. Therefore, divergence correction to accelerate the rate of convergence for its iterative solution is no longer needed. The utilization of direct solver has been verified previously for correctness by comparing the resulting solution to those given by analytical solution, as well as the solution come from the other numerical methods, for earth layered model, 2-D models and COMMEMI 3D-2 model. In this work, further verification resulted from recent comparison model of Dublin Test Model 1 (DTM1) is presented. (paper)

  19. Comparison of Prediction-Error-Modelling Criteria

    DEFF Research Database (Denmark)

    Jørgensen, John Bagterp; Jørgensen, Sten Bay


    Single and multi-step prediction-error-methods based on the maximum likelihood and least squares criteria are compared. The prediction-error methods studied are based on predictions using the Kalman filter and Kalman predictors for a linear discrete-time stochastic state space model, which is a r...

  20. Comparison of sparse point distribution models

    DEFF Research Database (Denmark)

    Erbou, Søren Gylling Hemmingsen; Vester-Christensen, Martin; Larsen, Rasmus


    This paper compares several methods for obtaining sparse and compact point distribution models suited for data sets containing many variables. These are evaluated on a database consisting of 3D surfaces of a section of the pelvic bone obtained from CT scans of 33 porcine carcasses. The superior m...

  1. Climate impact of transportation A model comparison

    NARCIS (Netherlands)

    Girod, B.; Vuuren, D.P. van; Grahn, M.; Kitous, A.; Kim, S.H.; Kyle, P.


    Transportation contributes to a significant and rising share of global energy use and GHG emissions. Therefore modeling future travel demand, its fuel use, and resulting CO2 emission is highly relevant for climate change mitigation. In this study we compare the baseline projections for global

  2. Global comparison of three greenhouse climate models

    NARCIS (Netherlands)

    Bavel, van C.H.M.; Takakura, T.; Bot, G.P.A.


    Three dynamic simulation models for calculating the greenhouse climate and its energy requirements for both heating and cooling were compared by making detailed computations for each of seven sets of data. The data sets ranged from a cold winter day, requiring heating, to a hot summer day, requiring

  3. Modeling cardiac β-adrenergic signaling with normalized-Hill differential equations: comparison with a biochemical model

    Directory of Open Access Journals (Sweden)

    Saucerman Jeffrey J


    Full Text Available Abstract Background New approaches are needed for large-scale predictive modeling of cellular signaling networks. While mass action and enzyme kinetic approaches require extensive biochemical data, current logic-based approaches are used primarily for qualitative predictions and have lacked direct quantitative comparison with biochemical models. Results We developed a logic-based differential equation modeling approach for cell signaling networks based on normalized Hill activation/inhibition functions controlled by logical AND and OR operators to characterize signaling crosstalk. Using this approach, we modeled the cardiac β1-adrenergic signaling network, including 36 reactions and 25 species. Direct comparison of this model to an extensively characterized and validated biochemical model of the same network revealed that the new model gave reasonably accurate predictions of key network properties, even with default parameters. Normalized Hill functions improved quantitative predictions of global functional relationships compared with prior logic-based approaches. Comprehensive sensitivity analysis revealed the significant role of PKA negative feedback on upstream signaling and the importance of phosphodiesterases as key negative regulators of the network. The model was then extended to incorporate recently identified protein interaction data involving integrin-mediated mechanotransduction. Conclusions The normalized-Hill differential equation modeling approach allows quantitative prediction of network functional relationships and dynamics, even in systems with limited biochemical data.

  4. Modeling cardiac β-adrenergic signaling with normalized-Hill differential equations: comparison with a biochemical model. (United States)

    Kraeutler, Matthew J; Soltis, Anthony R; Saucerman, Jeffrey J


    New approaches are needed for large-scale predictive modeling of cellular signaling networks. While mass action and enzyme kinetic approaches require extensive biochemical data, current logic-based approaches are used primarily for qualitative predictions and have lacked direct quantitative comparison with biochemical models. We developed a logic-based differential equation modeling approach for cell signaling networks based on normalized Hill activation/inhibition functions controlled by logical AND and OR operators to characterize signaling crosstalk. Using this approach, we modeled the cardiac β1-adrenergic signaling network, including 36 reactions and 25 species. Direct comparison of this model to an extensively characterized and validated biochemical model of the same network revealed that the new model gave reasonably accurate predictions of key network properties, even with default parameters. Normalized Hill functions improved quantitative predictions of global functional relationships compared with prior logic-based approaches. Comprehensive sensitivity analysis revealed the significant role of PKA negative feedback on upstream signaling and the importance of phosphodiesterases as key negative regulators of the network. The model was then extended to incorporate recently identified protein interaction data involving integrin-mediated mechanotransduction. The normalized-Hill differential equation modeling approach allows quantitative prediction of network functional relationships and dynamics, even in systems with limited biochemical data.

  5. Designing experiments and analyzing data a model comparison perspective

    CERN Document Server

    Maxwell, Scott E


    Through this book's unique model comparison approach, students and researchers are introduced to a set of fundamental principles for analyzing data. After seeing how these principles can be applied in simple designs, students are shown how these same principles also apply in more complicated designs. Drs. Maxwell and Delaney believe that the model comparison approach better prepares students to understand the logic behind a general strategy of data analysis appropriate for various designs; and builds a stronger foundation, which allows for the introduction of more complex topics omitt

  6. Direct MR Arthrography of the wrist in comparison with Arthroscopy: A prospective study on 125 patients

    International Nuclear Information System (INIS)

    Schmitt, R.; Christopoulos, G.; Coblenz, G.; Froehner, S.; Meier, R.; Lanz, U.; Krimmer, H.


    Objective: In literature the diagnostic value of MRI for detecting lesions of the carpal ligaments and the TFCC is judged controversially. The aim of the following study is to determine the diagnostic accuracy of direct MR arthrography for depicting and staging of intraarticular lesions of the wrist. Material and methods: One day before undergoing arthroscopy, 125 patients suffering from wrist pain were examined with direct MR arthrography in a prospective and blinded study. A mixture of contrast medium (iodine-containing contrast medium and gadopentetate in relation 200:1) was injected into both radiocarpal and midcarpal joints. The following sequences were acquired on a 1.5T scanner: coronal T1-weighted SE, coronal fat-saturated T1-weighted SE, coronal T1-/T2*-DESS-3D, and sagittal T2*-weighted MEDIC. MRI results were compared with arthroscopic findings using statistical analysis (SEN=sensitivity, SPE=specificity, PPV=positive predictive value, NPV=negative predictive value, ACC=accuracy). Results: In comparison to arthroscopy as the accepted diagnostic gold standard, the following results were found for MR arthrography. Detection of TFCC lesions: SEN 97.1%, SPE 96.4%, PPV 97.1%, NPV 96.4%, ACC 96.8%. Detection of complete tears of the scapholunate ligament: SEN 91.7%, SPE 100%, PPV 100%, NPV 99.1%, ACC 99.2%. Detection of partial tears: SEN 62.5%, SPE 100%, PPV 100%, NPV 94.8%, ACC 95.2%. Detection of cartilage defects: SEN 84.2%, SPE 96.2%, PPV 80%, NPV 97.1%, ACC 94.4%. In total, only three lesions of the lunotriquetral ligament were present. Conclusion: Direct MR arthrographic imaging is well suited for detecting intraarticular lesions of the wrist. The presented diagnostic results of MR arthrography are superior to the results of unenhanced MRI reported in the literature. Direct MR arthrography as a reliable diagnostic tool is strongly recommended if lesions of the scapholunate ligament and the triangular fibrocartilage complex are suspected. In contrast, an

  7. Animal models of transcranial direct current stimulation: Methods and mechanisms. (United States)

    Jackson, Mark P; Rahman, Asif; Lafon, Belen; Kronberg, Gregory; Ling, Doris; Parra, Lucas C; Bikson, Marom


    The objective of this review is to summarize the contribution of animal research using direct current stimulation (DCS) to our understanding of the physiological effects of transcranial direct current stimulation (tDCS). We comprehensively address experimental methodology in animal studies, broadly classified as: (1) transcranial stimulation; (2) direct cortical stimulation in vivo and (3) in vitro models. In each case advantages and disadvantages for translational research are discussed including dose translation and the overarching "quasi-uniform" assumption, which underpins translational relevance in all animal models of tDCS. Terminology such as anode, cathode, inward current, outward current, current density, electric field, and uniform are defined. Though we put key animal experiments spanning decades in perspective, our goal is not simply an exhaustive cataloging of relevant animal studies, but rather to put them in context of ongoing efforts to improve tDCS. Cellular targets, including excitatory neuronal somas, dendrites, axons, interneurons, glial cells, and endothelial cells are considered. We emphasize neurons are always depolarized and hyperpolarized such that effects of DCS on neuronal excitability can only be evaluated within subcellular regions of the neuron. Findings from animal studies on the effects of DCS on plasticity (LTP/LTD) and network oscillations are reviewed extensively. Any endogenous phenomena dependent on membrane potential changes are, in theory, susceptible to modulation by DCS. The relevance of morphological changes (galvanotropy) to tDCS is also considered, as we suggest microscopic migration of axon terminals or dendritic spines may be relevant during tDCS. A majority of clinical studies using tDCS employ a simplistic dose strategy where excitability is singularly increased or decreased under the anode and cathode, respectively. We discuss how this strategy, itself based on classic animal studies, cannot account for the

  8. Microscopic vision modeling method by direct mapping analysis for micro-gripping system with stereo light microscope. (United States)

    Wang, Yuezong; Zhao, Zhizhong; Wang, Junshuai


    We present a novel and high-precision microscopic vision modeling method, which can be used for 3D data reconstruction in micro-gripping system with stereo light microscope. This method consists of four parts: image distortion correction, disparity distortion correction, initial vision model and residual compensation model. First, the method of image distortion correction is proposed. Image data required by image distortion correction comes from stereo images of calibration sample. The geometric features of image distortions can be predicted though the shape deformation of lines constructed by grid points in stereo images. Linear and polynomial fitting methods are applied to correct image distortions. Second, shape deformation features of disparity distribution are discussed. The method of disparity distortion correction is proposed. Polynomial fitting method is applied to correct disparity distortion. Third, a microscopic vision model is derived, which consists of two models, i.e., initial vision model and residual compensation model. We derive initial vision model by the analysis of direct mapping relationship between object and image points. Residual compensation model is derived based on the residual analysis of initial vision model. The results show that with maximum reconstruction distance of 4.1mm in X direction, 2.9mm in Y direction and 2.25mm in Z direction, our model achieves a precision of 0.01mm in X and Y directions and 0.015mm in Z direction. Comparison of our model with traditional pinhole camera model shows that two kinds of models have a similar reconstruction precision of X coordinates. However, traditional pinhole camera model has a lower precision of Y and Z coordinates than our model. The method proposed in this paper is very helpful for the micro-gripping system based on SLM microscopic vision. Copyright © 2016 Elsevier Ltd. All rights reserved.

  9. Comparison of two ordinal prediction models

    DEFF Research Database (Denmark)

    Kattan, Michael W; Gerds, Thomas A


    system (i.e. old or new), such as the level of evidence for one or more factors included in the system or the general opinions of expert clinicians. However, given the major objective of estimating prognosis on an ordinal scale, we argue that the rival staging system candidates should be compared...... on their ability to predict outcome. We sought to outline an algorithm that would compare two rival ordinal systems on their predictive ability. RESULTS: We devised an algorithm based largely on the concordance index, which is appropriate for comparing two models in their ability to rank observations. We...... demonstrate our algorithm with a prostate cancer staging system example. CONCLUSION: We have provided an algorithm for selecting the preferred staging system based on prognostic accuracy. It appears to be useful for the purpose of selecting between two ordinal prediction models....

  10. MicroShield/ISOCS gamma modeling comparison.

    Energy Technology Data Exchange (ETDEWEB)

    Sansone, Kenneth R


    Quantitative radiological analysis attempts to determine the quantity of activity or concentration of specific radionuclide(s) in a sample. Based upon the certified standards that are used to calibrate gamma spectral detectors, geometric similarities between sample shape and the calibration standards determine if the analysis results developed are qualitative or quantitative. A sample analyzed that does not mimic a calibrated sample geometry must be reported as a non-standard geometry and thus the results are considered qualitative and not quantitative. MicroShieldR or ISOCSR calibration software can be used to model non-standard geometric sample shapes in an effort to obtain a quantitative analytical result. MicroShieldR and Canberras ISOCSR software contain several geometry templates that can provide accurate quantitative modeling for a variety of sample configurations. Included in the software are computational algorithms that are used to develop and calculate energy efficiency values for the modeled sample geometry which can then be used with conventional analysis methodology to calculate the result. The response of the analytical method and the sensitivity of the mechanical and electronic equipment to the radionuclide of interest must be calibrated, or standardized, using a calibrated radiological source that contains a known and certified amount of activity.

  11. A comparison of photographic, replication and direct clinical examination methods for detecting developmental defects of enamel

    Directory of Open Access Journals (Sweden)

    Pakshir Hamid-Reza


    Full Text Available Abstract Background Different methods have been used for detecting developmental defects of enamel (DDE. This study aimed to compare photographic and replication methods with the direct clinical examination method for detecting DDE in children's permanent incisors. Methods 110 8-10-year-old schoolchildren were randomly selected from an examined sample of 335 primary Shiraz school children. Modified DDE index was used in all three methods. Direct examinations were conducted by two calibrated examiners using flat oral mirrors and tongue blades. Photographs were taken using a digital SLR camera (Nikon D-80, macro lens, macro flashes, and matt flash filters. Impressions were taken using additional-curing silicon material and casts made in orthodontic stone. Impressions and models were both assessed using dental loupes (magnification=x3.5. Each photograph/impression/cast was assessed by two calibrated examiners. Reliability of methods was assessed using kappa agreement tests. Kappa agreement, McNemar's and two-sample proportion tests were used to compare results obtained by the photographic and replication methods with those obtained by the direct examination method. Results Of the 110 invited children, 90 were photographed and 73 had impressions taken. The photographic method had higher reliability levels than the other two methods, and compared to the direct clinical examination detected significantly more subjects with DDE (P = 0.002, 3.1 times more DDE (P Conclusion The photographic method was much more sensitive than direct clinical examination in detecting DDE and was the best of the three methods for epidemiological studies. The replication method provided less information about DDE compared to photography. Results of this study have implications for both epidemiological and detailed clinical studies on DDE.

  12. Visualizing the Impact of Art: An Update and Comparison of Current Psychological Models of Art Experience (United States)

    Pelowski, Matthew; Markey, Patrick S.; Lauring, Jon O.; Leder, Helmut


    The last decade has witnessed a renaissance of empirical and psychological approaches to art study, especially regarding cognitive models of art processing experience. This new emphasis on modeling has often become the basis for our theoretical understanding of human interaction with art. Models also often define areas of focus and hypotheses for new empirical research, and are increasingly important for connecting psychological theory to discussions of the brain. However, models are often made by different researchers, with quite different emphases or visual styles. Inputs and psychological outcomes may be differently considered, or can be under-reported with regards to key functional components. Thus, we may lose the major theoretical improvements and ability for comparison that can be had with models. To begin addressing this, this paper presents a theoretical assessment, comparison, and new articulation of a selection of key contemporary cognitive or information-processing-based approaches detailing the mechanisms underlying the viewing of art. We review six major models in contemporary psychological aesthetics. We in turn present redesigns of these models using a unified visual form, in some cases making additions or creating new models where none had previously existed. We also frame these approaches in respect to their targeted outputs (e.g., emotion, appraisal, physiological reaction) and their strengths within a more general framework of early, intermediate, and later processing stages. This is used as a basis for general comparison and discussion of implications and future directions for modeling, and for theoretically understanding our engagement with visual art. PMID:27199697

  13. A Comparison of Spread and Point-Source Multiple-Direction Estimation Techniques for High Latitude HF Direction Finding (United States)


    nouvel algorithme de goniometrie . Cet algorithme dit ä ’probabilite maximale de dispersion’ (PMD, SML en anglais pour ’spread maximum likelihood...and E layers to exist. These layers reflect radio waves in a predictable manner, thus facilitating reliable direction finding at those times

  14. Digital Marketing Maturity Models: Overview and Comparison


    Elina Bakhtieva


    The variety of available digital tools, strategies and activities might confuse and disorient even an experienced marketer. This applies in particular to B2B companies, which are usually less flexible in uptaking of digital technology than B2C companies. B2B companies are lacking a framework that corresponds to the specifics of the B2B business, and which helps to evaluate a company’s capabilities and to choose an appropriate path. A B2B digital marketing maturity model helps to fill this gap...

  15. Becker and Lomnitz rheological models: A comparison (United States)

    Mainardi, Francesco; Spada, Giorgio


    The viscoelastic material functions for the Becker and the Lomnitz rheological models, sometimes employed to describe the transient flow of rocks, are studied and compared. Their creep functions, which are known in a closed form, share a similar time dependence and asymptotic behavior. This is also found for the relaxation functions, obtained by solving numerically a Volterra equation of the second kind. We show that the two rheologies constitute a clear example of broadly similar creep and relaxation patterns associated with neatly distinct retardation spectra, for which analytical expressions are available.

  16. Theoretical intercomparison of multi-step direct reaction models and computational intercomparison of multi-step direct reaction models

    International Nuclear Information System (INIS)

    Koning, A.J.


    In recent years several statistical theories have been developed concerning multistep direct (MSD) nuclear reactions. In addition, dominant in applications is a whole class of semiclassical models that may be subsumed under the heading of 'generalized exciton models'. These are basically MSD-type extensions on top of compound-like concepts. In this report the relationship between their underlying statistical MSD-postulates is highlighted. A command framework is outlined that enables to generate the various MSD theories through assigning statistical properties to different parts of the nuclear Hamiltonian. Then it is shown that distinct forms of nuclear randomness are embodied in the mentioned theories. All these theories appear to be very similar at a qualitative level. In order to explain the high energy-tails and forward-peaked angular distribution typical for particles emitted in MSD reactions, it is imagined that the incident continuum particle stepwise looses its energy and direction in a sequence of collisions, thereby creating new particle-hole pairs in the target system. At each step emission may take place. The statistical aspect comes in because many continuum states are involved in the process. These are supposed to display chaotic behavior, the associated randomness assumption giving rise to important simplifications in the expression for MSD emission cross sections. This picture suggests that mentioned MSD models can be interpreted as a variant of essentially one and the same theory. However, this appears not to be the case. To show this usual MSD distinction within the composite reacting nucleus between the fast continuum particle and the residual interactions, the nucleons of the residual core are to be distinguished from those of the leading particle with the residual system. This distinction will turn out to be crucial to present analysis. 27 refs.; 5 figs.; 1 tab

  17. Comparison of direct shear and simple shear responses of municipal solid waste in USA

    KAUST Repository

    Fei, Xunchang


    Although large-size simple shear (SS) testing of municipal solid waste (MSW) may arguably provide a more realistic estimate of the shear strength (τ ) of MSW than the most commonly used direct shear (DS) testing, a systematic comparison between the shear responses of MSW obtained from the two testing methods is lacking. In this study, a large-size shear device was used to test identical MSW specimens sampled in USA in DS and SS. Eight DS tests and 11 SS tests were conducted at vertical effective stresses of 50–500 kPa. The stress–displacement response of MSW in SS testing was hyperbolic and a maximum shear stress was reached, whereas a maximum shear stress was not reached in most DS tests. The τ, effective friction angle (ϕ ′) and cohesion (c ′) of MSW were obtained from DS and SS tests by using a displacement failure criterion of 40 mm. τ in SS testing was found to be equal to or lower than τ in DS testing with ratios of τ between 73 and 101%. SS testing resulted in higher ϕ ′ but lower c ′ than DS testing. The shear strength parameters were lower than those obtained in previous studies from DS tests at 55 mm displacement.

  18. Systematic comparison of model polymer nanocomposite mechanics. (United States)

    Xiao, Senbo; Peter, Christine; Kremer, Kurt


    Polymer nanocomposites render a range of outstanding materials from natural products such as silk, sea shells and bones, to synthesized nanoclay or carbon nanotube reinforced polymer systems. In contrast to the fast expanding interest in this type of material, the fundamental mechanisms of their mixing, phase behavior and reinforcement, especially for higher nanoparticle content as relevant for bio-inorganic composites, are still not fully understood. Although polymer nanocomposites exhibit diverse morphologies, qualitatively their mechanical properties are believed to be governed by a few parameters, namely their internal polymer network topology, nanoparticle volume fraction, particle surface properties and so on. Relating material mechanics to such elementary parameters is the purpose of this work. By taking a coarse-grained molecular modeling approach, we study an range of different polymer nanocomposites. We vary polymer nanoparticle connectivity, surface geometry and volume fraction to systematically study rheological/mechanical properties. Our models cover different materials, and reproduce key characteristics of real nanocomposites, such as phase separation, mechanical reinforcement. The results shed light on establishing elementary structure, property and function relationship of polymer nanocomposites.

  19. Comparison of the Spatial Characteristics of Four Remotely Sensed Leaf Area Index Products over China: Direct Validation and Relative Uncertainties

    Directory of Open Access Journals (Sweden)

    Xinlu Li


    Full Text Available Leaf area index (LAI is a key input for many land surface models, ecological models, and yield prediction models. In order to make the model simulation and/or prediction more reliable and applicable, it is crucial to know the characteristics and uncertainties of remotely sensed LAI products before they are input into models. In this study, we conducted a comparison of four global remotely sensed LAI products—Global Land Surface Satellite (GLASS, Global LAI Product of Beijing Normal University (GLOBALBNU, Global LAI Map of Chinese Academy of Sciences (GLOBMAP, and Moderate-resolution Imaging Spectrometer (MODIS LAI, while the former three products are newly developed by three Chinese research groups on the basis of the MODIS land reflectance product over China between 2001 and 2011. Direct validation by comparing the four products to ground LAI observations both globally and over China demonstrates that GLASS LAI shows the best performance, with R2 = 0.70 and RMSE = 0.96 globally and R2 = 0.94 and RMSE = 0.61 over China; MODIS performs worst (R2 = 0.55, RMSE = 1.23 globally and R2 = 0.03, RMSE = 2.12 over China, and GLOBALBNU and GLOBMAP performs moderately. Comparison of the four products shows that they are generally consistent with each other, giving the smallest spatial correlation coefficient of 0.7 and the relative standard deviation around the order of 0.3. Compared with MODIS LAI, GLOBALBNU LAI is the most similar, followed by GLASS LAI and GLOBMAP. Large differences mainly occur in southern regions of China. LAI difference analysis indicates that evergreen needleleaf forest (ENF, woody savannas (SAV biome types and temperate dry hot summer, temperate warm summer dry winter and temperate hot summer no dry season climate types correspond to high standard deviation, while ENF and grassland (GRA biome types and temperate warm summer dry winter and cold dry winter warm summer climate types are responsible for the large relative standard

  20. Comparison of observed and modeled longwave radiances (United States)

    Stone, Kenneth; Coakley, J. A., Jr.


    Calculated LW radiances based on NMC profiles of temperature and humidities for the month of July 1985 are obtained using standard procedures for performing radiative transfer calculations, and are within 3 percent (against a standard deviation of 4 percent) for global daytime land comparsions and within 1 percent (against a standard deviation of 1.5 percent) for a case study located over North America. The calculated values over the global data set show a slight trend with the surface temperature, and since there is no obvious trend with the column amount of water vapor, it is argued that the trend with temperature is evidence that absorption by other components (i.e., CO2O3 and other trace gases not included in these calculations) in the model could be improved.

  1. Sport Education and Direct Instruction Units: Comparison of Student Knowledge Development in Athletics. (United States)

    Pereira, José; Araújo, Rui; Farias, Cláudio; Bessa, Cristiana; Mesquita, Isabel


    This study conducted a comparative analysis of students' knowledge development on athletics in Sport Education and in a Direct Instruction unit taking into account sex and initial skill level. The participants were an experienced Physical Education teacher and two sixth-grade classes totaling 47 students (25 boys and 22 girls). Each class was randomly placed in either Sport Education or Direct Instruction classes and participated in 20, 45-minutes lessons focused on shot put, hurdles and triple jump. Knowledge on athletics was assessed through a 25-items written and video-based test. The inter-group differences and improvements across time in the knowledge test were analyzed through the Mann-Whitney and Wilcoxon tests, respectively. There were significant knowledge improvements in both instructional approaches irrespective of students' gender and skill level. In Direct Instruction, the type of task organization, the high rates of repetition of movement patterns and feedback by the teacher were beneficial to student learning. In Sport Education, the autonomy granted to students in the control of the pace of task transitions by making on-going judgments on achievement of performance criteria, implicated students affectively and cognitively with the learning content. It was further supported that several models and teaching strategies should be taken into consideration when teaching Physical Education. Different approaches should be perceived as alternatives and teachers should retain the best in each according with the moment in the unit, student developmental stage, and the specific learning objectives in the task.

  2. Sport Education and Direct Instruction Units: Comparison of Student Knowledge Development in Athletics

    Directory of Open Access Journals (Sweden)

    José Pereira, Rui Araújo, Cláudio Farias, Cristiana Bessa, Isabel Mesquita


    Full Text Available This study conducted a comparative analysis of students’ knowledge development on athletics in Sport Education and in a Direct Instruction unit taking into account sex and initial skill level. The participants were an experienced Physical Education teacher and two sixth-grade classes totaling 47 students (25 boys and 22 girls. Each class was randomly placed in either Sport Education or Direct Instruction classes and participated in 20, 45-minutes lessons focused on shot put, hurdles and triple jump. Knowledge on athletics was assessed through a 25-items written and video-based test. The inter-group differences and improvements across time in the knowledge test were analyzed through the Mann-Whitney and Wilcoxon tests, respectively. There were significant knowledge improvements in both instructional approaches irrespective of students’ gender and skill level. In Direct Instruction, the type of task organization, the high rates of repetition of movement patterns and feedback by the teacher were beneficial to student learning. In Sport Education, the autonomy granted to students in the control of the pace of task transitions by making on-going judgments on achievement of performance criteria, implicated students affectively and cognitively with the learning content. It was further supported that several models and teaching strategies should be taken into consideration when teaching Physical Education. Different approaches should be perceived as alternatives and teachers should retain the best in each according with the moment in the unit, student developmental stage, and the specific learning objectives in the task.

  3. Examining Attitudes of Students Regarding the Sports Education Model and Direct Teaching Model (United States)

    Bilgin, Nevruz; Dalkiran, Oguzhan


    The aim of the research was to investigate the effects of sports education model and direct teaching model on the attitudes of the students, and the differences among the attitudes of students. The study group of the research included 29 students from 6th and 7th grade of a secondary school in the 2015-2016 academic years. The experimental group…

  4. Foreign Direct Investments in Central Asian Energy: A CGE Model

    Directory of Open Access Journals (Sweden)

    Michael P. BARRY


    Full Text Available Turkmenistan, Uzbekistan, and Kazakhstan have adopted significant legislative changes since the fall of the former Soviet Union in an effort to attract foreign direct investment into their energy sectors. Of the three republics, Kazakhstan has been the most successful in attracting foreign interest, but all three republics face significant challenges in further development of oil and gas infrastructure. Even if these countries are completely successful in bringing in foreign investment, a question will remain: who wins and who loses in these countries. Using updated data, this paper will use a computable general equilibrium model to measure the effects of FDI into Central Asia. Results of the model suggest that the region would be better off overall from foreign investment in its natural gas sector, due mostly to improvements in overall production efficiency and its overall terms of trade. However, the gain in the natural gas sector would come at the expense of production and net exports of non-petroleum related industries.

  5. Interactive comparison of hypothesis tests for statistical model checking

    NARCIS (Netherlands)

    de Boer, Pieter-Tjerk; Reijsbergen, D.P.; Scheinhardt, Willem R.W.


    We present a web-based interactive comparison of hypothesis tests as are used in statistical model checking, providing users and tool developers with more insight into their characteristics. Parameters can be modified easily and their influence is visualized in real time; an integrated simulation

  6. A copula method for modeling directional dependence of genes

    Directory of Open Access Journals (Sweden)

    Park Changyi


    Full Text Available Abstract Background Genes interact with each other as basic building blocks of life, forming a complicated network. The relationship between groups of genes with different functions can be represented as gene networks. With the deposition of huge microarray data sets in public domains, study on gene networking is now possible. In recent years, there has been an increasing interest in the reconstruction of gene networks from gene expression data. Recent work includes linear models, Boolean network models, and Bayesian networks. Among them, Bayesian networks seem to be the most effective in constructing gene networks. A major problem with the Bayesian network approach is the excessive computational time. This problem is due to the interactive feature of the method that requires large search space. Since fitting a model by using the copulas does not require iterations, elicitation of the priors, and complicated calculations of posterior distributions, the need for reference to extensive search spaces can be eliminated leading to manageable computational affords. Bayesian network approach produces a discretely expression of conditional probabilities. Discreteness of the characteristics is not required in the copula approach which involves use of uniform representation of the continuous random variables. Our method is able to overcome the limitation of Bayesian network method for gene-gene interaction, i.e. information loss due to binary transformation. Results We analyzed the gene interactions for two gene data sets (one group is eight histone genes and the other group is 19 genes which include DNA polymerases, DNA helicase, type B cyclin genes, DNA primases, radiation sensitive genes, repaire related genes, replication protein A encoding gene, DNA replication initiation factor, securin gene, nucleosome assembly factor, and a subunit of the cohesin complex by adopting a measure of directional dependence based on a copula function. We have compared

  7. Depth-kymography of vocal fold vibrations : part II. Simulations and direct comparisons with 3D profile measurements

    NARCIS (Netherlands)

    de Mul, Frits F. M.; George, Nibu A.; Qiu, Qingjun; Rakhorst, Gerhard; Schutte, Harm K.


    We report novel direct quantitative comparisons between 3D profiling measurements and simulations of human vocal fold vibrations. Until now, in human vocal folds research, only imaging in a horizontal plane was possible. However, for the investigation of several diseases, depth information is

  8. Box & Jenkins Model Identification:A Comparison of Methodologies

    Directory of Open Access Journals (Sweden)

    Maria Augusta Soares Machado


    Full Text Available This paper focuses on a presentation of a comparison of a neuro-fuzzy back propagation network and Forecast automatic model Identification to identify automatically Box & Jenkins non seasonal models.Recently some combinations of neural networks and fuzzy logic technologies have being used to deal with uncertain and subjective problems. It is concluded on the basis of the obtained results that this type of approach is very powerful to be used.

  9. A comparison of two models for scaling health indicators. (United States)

    Kind, P


    The measurement properties of a health status indicator are closely related to the scaling model on which it is based. The Thurstone and Bradley-Terry models are applied to paired comparisons data which had been used to scale the sleep category of the Nottingham Health Profile. The data in their original form are shown to be inadequately represented by either model. Weaknesses in the data are identified and the two scaling models are applied to the amended data. The results of applying two sets of scale values are compared.

  10. Comparison of four different models of vortex generators

    DEFF Research Database (Denmark)

    Fernandez, U.; Réthoré, Pierre-Elouan; Sørensen, Niels N.


    Actuator Vortex Generator Model (AcVG), is based on the lifting force theory of Bender, Anderson and Yagle, the BAY Model, which provides an efficient method for computational fluid dynamic (CFD) simulations of flow with VGs, and the forces are applied into the computational domain using the actuator shape...... in the center of the test section. The fourth model, used as a quantitative comparison, is the analytical model of the primary vortex based in the helical structure of longitudinal embedded vortex, which can reduce the complex flow to merely four parameters: circulation, convection velocity, vortex core radius...

  11. Data-directed RNA secondary structure prediction using probabilistic modeling. (United States)

    Deng, Fei; Ledda, Mirko; Vaziri, Sana; Aviran, Sharon


    Structure dictates the function of many RNAs, but secondary RNA structure analysis is either labor intensive and costly or relies on computational predictions that are often inaccurate. These limitations are alleviated by integration of structure probing data into prediction algorithms. However, existing algorithms are optimized for a specific type of probing data. Recently, new chemistries combined with advances in sequencing have facilitated structure probing at unprecedented scale and sensitivity. These novel technologies and anticipated wealth of data highlight a need for algorithms that readily accommodate more complex and diverse input sources. We implemented and investigated a recently outlined probabilistic framework for RNA secondary structure prediction and extended it to accommodate further refinement of structural information. This framework utilizes direct likelihood-based calculations of pseudo-energy terms per considered structural context and can readily accommodate diverse data types and complex data dependencies. We use real data in conjunction with simulations to evaluate performances of several implementations and to show that proper integration of structural contexts can lead to improvements. Our tests also reveal discrepancies between real data and simulations, which we show can be alleviated by refined modeling. We then propose statistical preprocessing approaches to standardize data interpretation and integration into such a generic framework. We further systematically quantify the information content of data subsets, demonstrating that high reactivities are major drivers of SHAPE-directed predictions and that better understanding of less informative reactivities is key to further improvements. Finally, we provide evidence for the adaptive capability of our framework using mock probe simulations. © 2016 Deng et al.; Published by Cold Spring Harbor Laboratory Press for the RNA Society.

  12. Expanding the developmental models of writing: A direct and indirect effects model of developmental writing (DIEW) (United States)

    Kim, Young-Suk Grace; Schatschneider, Christopher


    We investigated direct and indirect effects of component skills on writing (DIEW) using data from 193 children in Grade 1. In this model, working memory was hypothesized to be a foundational cognitive ability for language and cognitive skills as well as transcription skills, which, in turn, contribute to writing. Foundational oral language skills (vocabulary and grammatical knowledge) and higher-order cognitive skills (inference and theory of mind) were hypothesized to be component skills of text generation (i.e., discourse-level oral language). Results from structural equation modeling largely supported a complete mediation model among four variations of the DIEW model. Discourse-level oral language, spelling, and handwriting fluency completely mediated the relations of higher-order cognitive skills, foundational oral language, and working memory to writing. Moreover, language and cognitive skills had both direct and indirect relations to discourse-level oral language. Total effects, including direct and indirect effects, were substantial for discourse-level oral language (.46), working memory (.43), and spelling (.37), followed by vocabulary (.19), handwriting (.17), theory of mind (.12), inference (.10), and grammatical knowledge (.10). The model explained approximately 67% of variance in writing quality. These results indicate that multiple language and cognitive skills make direct and indirect contributions, and it is important to consider both direct and indirect pathways of influences when considering skills that are important to writing. PMID:28260812

  13. A randomized direct comparison of the pharmacokinetics and pharmacodynamics of apixaban and rivaroxaban

    Directory of Open Access Journals (Sweden)

    Frost C


    Full Text Available Charles Frost,1 Yan Song,1 Yu Chen Barrett,1 Jessie Wang,2 Janice Pursley,3 Rebecca A Boyd,4 Frank LaCreta1 1Exploratory Clinical and Translational Research, 2Exploratory Development Global Biometric Sciences, 3Analytical and Bioanalytical Development, Bristol-Myers Squibb Company, Princeton, NJ, USA; 4Global Innovative Pharma Business Clinical Pharmacology, Pfizer Inc., Groton, CT, USA Background: Currently, there are no direct comparisons of apixaban and rivaroxaban, two new oral direct factor Xa inhibitors approved for management of thromboembolic disorders. Objective: Compare the pharmacokinetics and anti-factor Xa activity (AXA of apixaban and rivaroxaban. Methods: In this randomized, open-label, two-period, two-treatment crossover study, healthy subjects (N=14 received apixaban 2.5 mg twice daily (BID and rivaroxaban 10 mg once daily (QD for 4 days with a ≥4.5-day washout. Plasma samples were obtained for pharmacokinetic and AXA assessments; parameters were calculated using noncompartmental methods. Results: Median time-to-maximum concentration was 2 hours for both compounds, and the mean half-life was 8.7 and 7.9 hours for apixaban and rivaroxaban, respectively. Daily exposure, the area under the curve (AUC(0–24, appeared similar for rivaroxaban (1,094 ng · h/mL and apixaban (935 ng · h/mL, whereas mean peak-to-trough plasma concentration ratio was 3.6-fold greater for rivaroxaban (16.9 than apixaban (4.7. Coefficient of variation for exposure parameters (AUC0–24, Cmax, Cmin was 20%–24% for apixaban versus 29%–46% for rivaroxaban. Peak AXA, AXA AUC(0–24, and AXA fluctuation were ~2.5-, 1.3-, and 3.5-fold higher for rivaroxaban than apixaban, respectively. Trough concentrations and AXA were lower for rivaroxaban (10 ng/mL and 0.17 IU/mL vs 17 ng/mL and 0.24 IU/mL for apixaban, respectively. Rivaroxaban exhibited a steeper concentration–AXA response (slope: 0.0172 IU/ng vs 0.0134 IU/ng for apixaban, P<0.0001. Conclusion

  14. Anterior and posterior compartment 3D endovaginal ultrasound anatomy based on direct histologic comparison. (United States)

    Shobeiri, S Abbas; White, Dena; Quiroz, Lieschen H; Nihira, Mikio A


    We used direct histologic comparison to validate the use of 3D endovaginal ultrasound (EVUS) as a novel and emerging technology for evaluating the structures found in the anterior and posterior pelvic floor compartments. A young nulliparous female pelvis specimen was dissected and histologic slides were prepared by making 8-Micron-thick sagittal cuts. The slides were stained with Mallory trichrome and arranged to form large sections encompassing each anterior and posterior sagittal plane. Healthy nulliparous women underwent 3D EVUS to obtain 3D cubes of the anterior and posterior compartments. Two investigators independently evaluated the anterior and posterior midsagittal structures. The investigators mutually viewed the images and calculated urethral and anal sphincter measurements. Thirty-one nulliparous women underwent 3D EVUS; 77% of the participants were Caucasian, with mean age 31.8 [standard deviation (SD) 5.8] and mean body mass index (BMI) of 28.5 (SD 7.9). The following mean (SD) measurements were obtained: urethral length 36 mm (± 5); striated urogenital sphincter area 0.6 cm(2) (± 0.16); longitudinal and circular smooth muscle area 1.1 cm(2) (± 0.4); urethral complex width 14 mm (± 2); urethral complex area 1.3 cm(2) (± 0.4); internal anal sphincter length 26 mm (± 4); internal anal sphincter thickness 3.2 mm (± 0.8); and rectovaginal septum length 31 mm (± 5). The agreement for visualization of structures was as follows: vesical trigone 96% (κ = 0.65), trigonal ring 94% (κ = 0.8), trigonal plate 84% (κ = 0.6); longitudinal and circular smooth muscle 100%; compressor urethra 97% (κ = 0.85); striated urogenital sphincter 97% (κ = 0.85); rectovaginal septum 100%; internal anal sphincter 100%; external anal sphincter subdivisions 100%. Three-dimensional EVUS can be used to visualize structures of the anterior and posterior compartments in nullipara.

  15. Measurement of the optical density of packable composites: comparison between direct and indirect digital systems

    Directory of Open Access Journals (Sweden)

    Graziottin Luiz Felipe Rodrigues


    Full Text Available The aim of this study was to measure the optical density of four packable composite resins with widths of 1, 2, 3 and 4 mm, by means of Digora® (direct and DentScan DentView® (indirect digital imaging systems, in order to compare both methods. Twenty acrylic plates, with the proposed thicknesses, were used, each one containing a sample of each resin. Each acrylic plate was radiographed three times, under a standardized technique. For the Digora® system, an optical plate was used under each resin sample, and, for the DentScan DentView® system, occlusal films were employed, totalizing 60 exposures for each system. Optical plates and films were scanned and three consecutive optical readouts were carried out, totalizing 1,440 readouts. The results were submitted to statistical analysis and revealed that the average optical density of the four resins always increased as thickness increased. Regarding the comparisons between the composite resins, in both analysis the resin with the greater optical density was SurefilTM followed by ProdigyTM Condensable, AlertTM and Solitaire®. The correlations between the results of Digora® and DentScan DentView® were significant for the different thicknesses and materials. The observed tendency is that as the values obtained with the Digora® system increase, so do the values obtained with DentScan DentView®. While thickness increased, the values of optical density in both Digora® and DentScan DentView® tended to approach each other. The Digora® system presented smaller amplitude between the results obtained in adjacent thicknesses.

  16. Experimental comparison of two PV direct-coupled solar water heating systems with the traditional system

    International Nuclear Information System (INIS)

    Ji, Jie; Wang, Yanqiu; Yuan, Weiqi; Sun, Wei; He, Wei; Guo, Chao


    Highlights: • A design approach of PV-coupled solar water heating system (SWHS) is presented. • Two different designs of PV modules are proposed and investigated. • A comparative test rig of PV-coupled SWHS and traditional SWHS is set up. • A flow rate increasing with solar irradiation is recommended. - Abstract: Simple and reliable, PV direct-coupled DC pumps are promising in solar water heating systems (SWHS). However, there is limited experimental data on the performance comparison of PV-coupled SWHS with traditional SWHS. Hence in this study, a comparative test rig is set up to measure and analyze the performance of the PV-coupled SWHS and the traditional system under the same conditions. The experimental results show that on sunny days the PV-coupled SWHS has similar daily thermal efficiency as the traditional SWHS, and slightly higher efficiency after improving the design of the PV module. Under low irradiation, the PV-coupled SWHS gains much more heat than the traditional SWHS, which indicates the potential of the PV-coupled SWHS having much higher efficiency than the traditional SWHS on cloudy days. In order to improve the performance of the PV-coupled SWHS, two different designs of PV module are proposed, and their influence on the pump startup characteristics, the flow rate profile, and the thermal efficiency of the system is investigated. It is found that the modified design of the PV module can reduce the requirement of PV cells and increase the efficiency of the system

  17. A comparison of food crispness based on the cloud model. (United States)

    Wang, Minghui; Sun, Yonghai; Hou, Jumin; Wang, Xia; Bai, Xue; Wu, Chunhui; Yu, Libo; Yang, Jie


    The cloud model is a typical model which transforms the qualitative concept into the quantitative description. The cloud model has been used less extensively in texture studies before. The purpose of this study was to apply the cloud model in food crispness comparison. The acoustic signals of carrots, white radishes, potatoes, Fuji apples, and crystal pears were recorded during compression. And three time-domain signal characteristics were extracted, including sound intensity, maximum short-time frame energy, and waveform index. The three signal characteristics and the cloud model were used to compare the crispness of the samples mentioned above. The crispness based on the Ex value of the cloud model, in a descending order, was carrot > potato > white radish > Fuji apple > crystal pear. To verify the results of the acoustic signals, mechanical measurement and sensory evaluation were conducted. The results of the two verification experiments confirmed the feasibility of the cloud model. The microstructures of the five samples were also analyzed. The microstructure parameters were negatively related with crispness (p cloud model method can be used for crispness comparison of different kinds of foods. The method is more accurate than the traditional methods such as mechanical measurement and sensory evaluation. The cloud model method can also be applied to other texture studies extensively. © 2017 Wiley Periodicals, Inc.

  18. Modeling of pyrolytic laser direct writing: Noncoherent structures and instabilities (United States)

    Arnold, N.; Kargl, P. B.; Bäuerle, D.


    Three-dimensional simulations of pyrolytic laser direct writing from gas-phase precursors are presented. They are based on a fast method for the calculation of temperature distributions induced by an energy beam in deposits of arbitrary shape. Analytical approximations, fast Fourier transform, and the multigrid technique are combined in the algorithm. Temperature dependences of the absorptivities and heat conductivities of the deposit and the substrate have been taken into account. Self-consistent modeling of the growth process allows one to explain oscillations in the height and width of lines caused by the feedback between the shape of the deposit, the temperature distribution, and the growth rate. For the deposition of W from an admixture of WCl6+H2 and a-SiO2 substrates, the oscillations originate from a sharp increase in the absorptivity of the deposit with temperature. With the deposition of Si from SiH4, or C from CH4, C2H2, and C2H4, onto a-SiO2, the oscillations are related to the large ratio of height/width of the deposit and the increase in temperature on its upper surface. This increase also explains the transition from line-type to fiber-type growth. The hysteresis of this transition with respect to laser power and scanning velocity is explained as well. The same algorithm can be used in the modeling of pyrolytic etching and e-beam microprocessing when the feedback between the temperature distributions and changes in the processing geometry is important.

  19. Goal Directed Model Inversion: A Study of Dynamic Behavior (United States)

    Colombano, Silvano P.; Compton, Michael; Raghavan, Bharathi; Lum, Henry, Jr. (Technical Monitor)


    Goal Directed Model Inversion (GDMI) is an algorithm designed to generalize supervised learning to the case where target outputs are not available to the learning system. The output of the learning system becomes the input to some external device or transformation, and only the output of this device or transformation can be compared to a desired target. The fundamental driving mechanism of GDMI is to learn from success. Given that a wrong outcome is achieved, one notes that the action that produced that outcome 0 "would have been right if the outcome had been the desired one." The algorithm then proceeds as follows: (1) store the action that produced the wrong outcome as a "target" (2) redefine the wrong outcome as a desired goal (3) submit the new desired goal to the system (4) compare the new action with the target action and modify the system by using a suitable algorithm for credit assignment (Back propagation in our example) (5) resubmit the original goal. Prior publications by our group in this area focused on demonstrating empirical results based on the inverse kinematic problem for a simulated robotic arm. In this paper we apply the inversion process to much simpler analytic functions in order to elucidate the dynamic behavior of the system and to determine the sensitivity of the learning process to various parameters. This understanding will be necessary for the acceptance of GDMI as a practical tool.

  20. A comparison of newborn stylized and tomographic models for dose assessment in paediatric radiology

    International Nuclear Information System (INIS)

    Staton, R J; Pazik, F D; Nipper, J C; Williams, J L; Bolch, W E


    Establishment of organ doses from diagnostic and interventional examinations is a key component to quantifying the radiation risks from medical exposures and for formulating corresponding dose-reduction strategies. Radiation transport models of human anatomy provide a convenient method for simulating radiological examinations. At present, two classes of models exist: stylized mathematical models and tomographic voxel models. In the present study, organ dose comparisons are made for projection radiographs of both a stylized and a tomographic model of the newborn patient. Sixteen separate radiographs were simulated for each model at x-ray technique factors typical of newborn examinations: chest, abdomen, thorax and head views in the AP, PA, left LAT and right LAT projection orientation. For AP and PA radiographs of the torso (chest, abdomen and thorax views), the effective dose assessed for the tomographic model exceeds that for the stylized model with per cent differences ranging from 19% (AP abdominal view) to 43% AP chest view. In contrast, the effective dose for the stylized model exceeds that for the tomographic model for all eight lateral views including those of the head, with per cent differences ranging from 9% (LLAT chest view) to 51% (RLAT thorax view). While organ positioning differences do exist between the models, a major factor contributing to differences in effective dose is the models' exterior trunk shape. In the tomographic model, a more elliptical shape is seen thus providing for less tissue shielding for internal organs in the AP and PA directions, with corresponding increased tissue shielding in the lateral directions. This observation is opposite of that seen in comparisons of stylized and tomographic models of the adult

  1. Energy efficient routing protocols for wireless sensor networks: comparison and future directions

    Directory of Open Access Journals (Sweden)

    Loganathan Murukesan


    Full Text Available Wireless sensor network consists of nodes with limited resources. Hence, it is important to design protocols or algorithms which increases energy efficiency in order to improve the network lifetime. In this paper, techniques used in the network layer (routing of the internet protocol stack to achieve energy efficiency are reviewed. Usually, the routing protocols are classified into four main schemes: (1 Network Structure, (2 Communication Model, (3 Topology Based, and (4 Reliable Routing. In this work, only network structure based routing protocols are reviewed due to the page constraint. Besides, this type of protocols are much popular among the researchers since they are fairly simple to implement and produce good results as presented in this paper. Also, the pros and cons of each protocols are presented. Finally, the paper concludes with possible further research directions.

  2. Statistical mechanics of directed models of polymers in the square lattice

    CERN Document Server

    Rensburg, J V


    Directed square lattice models of polymers and vesicles have received considerable attention in the recent mathematical and physical sciences literature. These are idealized geometric directed lattice models introduced to study phase behaviour in polymers, and include Dyck paths, partially directed paths, directed trees and directed vesicles models. Directed models are closely related to models studied in the combinatorics literature (and are often exactly solvable). They are also simplified versions of a number of statistical mechanics models, including the self-avoiding walk, lattice animals and lattice vesicles. The exchange of approaches and ideas between statistical mechanics and combinatorics have considerably advanced the description and understanding of directed lattice models, and this will be explored in this review. The combinatorial nature of directed lattice path models makes a study using generating function approaches most natural. In contrast, the statistical mechanics approach would introduce...

  3. Evidence-based treatments for depression and anxiety versus treatment-as-usual: a meta-analysis of direct comparisons. (United States)

    Wampold, Bruce E; Budge, Stephanie L; Laska, Kevin M; Del Re, A C; Baardseth, Timothy P; Fluckiger, Christoph; Minami, Takuya; Kivlighan, D Martin; Gunn, Wade


    The aim of this study was to examine the relative efficacy of evidence-based treatments (EBTs) versus treatment-as-usual (TAU) in routine care for anxiety and depression in adults. A computerized search of studies that directly compared an EBT with a TAU was conducted. Meta-analytic methods were used to estimate effectiveness of EBTs relative to TAU and to model how various confounding variables impacted the results of this comparative research. A total of 14 studies were included in the final meta-analysis. There was significant heterogeneity in the TAU conditions, which ranged from unknown and/or minimal mental health treatment to psychotherapeutic interventions provided by trained professionals. Although the effect for EBT vs. TAU was significantly greater than zero, the effect for EBT vs. TAUs that were psychotherapeutic interventions was not statistically different from zero. Heterogeneity of TAU conditions in this meta-analysis highlight the importance of clarifying the research questions being asked when investigating and drawing conclusions from EBT-TAU comparisons. Researchers need to clarify if they are comparing an EBT to psychotherapeutic services in routine care or to minimal mental health services. Extant research on EBT versus TAU reveals that there is insufficient evidence to recommend the transportation of EBTs for anxiety and depression to routine care, particularly when the routine care involves psychotherapeutic services. Copyright © 2011 Elsevier Ltd. All rights reserved.

  4. An Empirical Comparison of Default Swap Pricing Models

    NARCIS (Netherlands)

    P. Houweling (Patrick); A.C.F. Vorst (Ton)


    textabstractAbstract: In this paper we compare market prices of credit default swaps with model prices. We show that a simple reduced form model with a constant recovery rate outperforms the market practice of directly comparing bonds' credit spreads to default swap premiums. We find that the

  5. Comparison of empirical models and laboratory saturated hydraulic ...

    African Journals Online (AJOL)

    Numerous methods for estimating soil saturated hydraulic conductivity exist, which range from direct measurement in the laboratory to models that use only basic soil properties. A study was conducted to compare laboratory saturated hydraulic conductivity (Ksat) measurement and that estimated from empirical models.

  6. Quantitative comparison of canopy conductance models using a Bayesian approach (United States)

    Samanta, S.; Clayton, M. K.; Mackay, D. S.; Kruger, E. L.; Ewers, B. E.


    A quantitative model comparison methodology based on deviance information criterion, a Bayesian measure of the trade-off between model complexity and goodness of fit, is developed and demonstrated by comparing semiempirical transpiration models. This methodology accounts for parameter and prediction uncertainties associated with such models and facilitates objective selection of the simplest model, out of available alternatives, which does not significantly compromise the ability to accurately model observations. We use this methodology to compare various Jarvis canopy conductance model configurations, embedded within a larger transpiration model, against canopy transpiration measured by sap flux. The results indicate that descriptions of the dependence of stomatal conductance on vapor pressure deficit, photosynthetic radiation, and temperature, as well as the gradual variation in canopy conductance through the season are essential in the transpiration model. Use of soil moisture was moderately significant, but only when used with a hyperbolic vapor pressure deficit relationship. Subtle differences in model quality could be clearly associated with small structural changes through the use of this methodology. The results also indicate that increments in model complexity are not always accompanied by improvements in model quality and that such improvements are conditional on model structure. Possible application of this methodology to compare complex semiempirical models of natural systems in general is also discussed.

  7. Aerosol properties and their direct radiative forcing: GEOS-Chem-APM simulations and comparisons (United States)

    Ma, X.; Yu, F.; Luo, G.


    Aerosol direct radiative forcing (DRF) remains to have large uncertainty, which could be attributable to uncertainties in precursor gases and primary particles emissions, physical and chemical processes parameterizations, meteorological condition and surface properties, and aerosol properties (concentration, size, composition, mixing state), etc. Therefore, work to reduce such uncertainties is of particular interest. This study is based on GEOS-Chem APM model, a global chemical transport model with up-to-date emission inventories, detailed chemistry and size-resolved microphysics. GEOS-Chem is driven by assimilated meteorology which is presumably more reasonable compared to the model-produced meteorology. GEOS-Chem-APM is a global multi-type, multi-component, size-resolved microphysics model (Yu and Luo, Atmos. Chem. Phys., 9, 7691-7710, 2009), including state-of-the-art nucleation schemes and condensation of low volatile secondary organic compounds from successive oxidation aging. The prognostic aerosol species include second particle (SP, containing sulfate, ammonia, nitrate, SOA, and MSA), sea salt, mineral dust, black carbon (BC), and primary organic carbon. The model has been well validated in terms of various observational datasets. We extended the GEOS-Chem APM model by coupling a radiation transfer model, to investigate the radiative forcing of aerosols and uncertainties. The optical properties required for radiation are calculated using Mie theory in which shell/core configuration could be treated and compared with various measurements. We derived the total and anthropogenic aerosol radiative forcing, and examined the dependencies of the radiative forcing on different affecting factors. We found that aerosol absorption optical depth (AAOD) at 550 nm enhances by 35% (from 2.31e-3 to 3.12e-3) when hydrophobic BC coated by hygroscopic SP species (i.e., semi-external mixing), rather than external mixing, is considered. The corresponding all-sky TOA RF due to

  8. Modeling Uncertainty in Climate Change: A Multi-Model Comparison

    Energy Technology Data Exchange (ETDEWEB)

    Gillingham, Kenneth; Nordhaus, William; Anthoff, David; Blanford, Geoffrey J.; Bosetti, Valentina; Christensen, Peter; McJeon, Haewon C.; Reilly, J. M.; Sztorc, Paul


    The economics of climate change involves a vast array of uncertainties, complicating both the analysis and development of climate policy. This study presents the results of the first comprehensive study of uncertainty in climate change using multiple integrated assessment models. The study looks at model and parametric uncertainties for population, total factor productivity, and climate sensitivity and estimates the pdfs of key output variables, including CO2 concentrations, temperature, damages, and the social cost of carbon (SCC). One key finding is that parametric uncertainty is more important than uncertainty in model structure. Our resulting pdfs also provide insight on tail events.

  9. Direct coupling of a genome-scale microbial in silico model and a groundwater reactive transport model

    International Nuclear Information System (INIS)

    Fang, Yilin; Scheibe, Timothy D.; Mahadevan, Radhakrishnan; Garg, Srinath; Long, Philip E.; Lovley, Derek R.


    modeling system is designed in such a way that constraint-based models targeting different microorganisms or competing organism communities can be easily plugged into the system. Constraint-based modeling is very costly given the size of a genome-scale reaction network. To save computation time, a binary tree is traversed to examine the concentration and solution pool generated during the simulation in order to decide whether the constraint-based model should be called. We also show preliminary results from the integrated model including a comparison of the direct and indirect coupling approaches.

  10. Direct coupling of a genome-scale microbial in silico model and a groundwater reactive transport model (United States)

    Fang, Yilin; Scheibe, Timothy D.; Mahadevan, Radhakrishnan; Garg, Srinath; Long, Philip E.; Lovley, Derek R.


    modeling system is designed in such a way that constraint-based models targeting different microorganisms or competing organism communities can be easily plugged into the system. Constraint-based modeling is very costly given the size of a genome-scale reaction network. To save computation time, a binary tree is traversed to examine the concentration and solution pool generated during the simulation in order to decide whether the constraint-based model should be called. We also show preliminary results from the integrated model including a comparison of the direct and indirect coupling approaches and evaluated the ability of the approach to simulate field experiment.

  11. Hysteresis and creep: Comparison between a power-law model and Kuhnen's model

    Energy Technology Data Exchange (ETDEWEB)

    Oliveri, Alberto; Stellino, Flavio; Parodi, Mauro; Storace, Marco, E-mail:


    In this paper we analyze some properties of a recently proposed model of hysteresis and creep (related to a circuit model, whose only nonlinear element is based on a power law) and compare it with the well-known Kuhnen's model. A first qualitative comparison relies on the analysis of the behavior of the elementary cell of each model. Their responses to step inputs (which allow to better evidence the creep effect) are analyzed and compared. Then, a quantitative comparison is proposed, based on the fitting performances of the two models on experimental data measured from a commercial piezoelectric actuator.

  12. Tumorigenic fragments of APC cause dominant defects in directional cell migration in multiple model systems

    Directory of Open Access Journals (Sweden)

    Scott A. Nelson


    Nonsense mutations that result in the expression of truncated, N-terminal, fragments of the adenomatous polyposis coli (APC tumour suppressor protein are found in most sporadic and some hereditary colorectal cancers. These mutations can cause tumorigenesis by eliminating β-catenin-binding sites from APC, which leads to upregulation of β-catenin and thereby results in the induction of oncogenes such as MYC. Here we show that, in three distinct experimental model systems, expression of an N-terminal fragment of APC (N-APC results in loss of directionality, but not speed, of cell motility independently of changes in β-catenin regulation. We developed a system to culture and fluorescently label live pieces of gut tissue to record high-resolution three-dimensional time-lapse movies of cells in situ. This revealed an unexpected complexity of normal gut cell migration, a key process in gut epithelial maintenance, with cells moving with spatial and temporal discontinuity. Quantitative comparison of gut tissue from wild-type mice and APC heterozygotes (APCMin/+; multiple intestinal neoplasia model demonstrated that cells in precancerous epithelia lack directional preference when moving along the crypt-villus axis. This effect was reproduced in diverse experimental systems: in developing chicken embryos, mesoderm cells expressing N-APC failed to migrate normally; in amoeboid Dictyostelium, which lack endogenous APC, expressing an N-APC fragment maintained cell motility, but the cells failed to perform directional chemotaxis; and multicellular Dictyostelium slug aggregates similarly failed to perform phototaxis. We propose that N-terminal fragments of APC represent a gain-of-function mutation that causes cells within tissue to fail to migrate directionally in response to relevant guidance cues. Consistent with this idea, crypts in histologically normal tissues of APCMin/+ intestines are overpopulated with cells, suggesting that a lack of migration might cause cell

  13. Direct comparison of quantum and simulated annealing on a fully connected Ising ferromagnet (United States)

    Wauters, Matteo M.; Fazio, Rosario; Nishimori, Hidetoshi; Santoro, Giuseppe E.


    We compare the performance of quantum annealing (QA, through Schrödinger dynamics) and simulated annealing (SA, through a classical master equation) on the p -spin infinite range ferromagnetic Ising model, by slowly driving the system across its equilibrium, quantum or classical, phase transition. When the phase transition is second order (p =2 , the familiar two-spin Ising interaction) SA shows a remarkable exponential speed-up over QA. For a first-order phase transition (p ≥3 , i.e., with multispin Ising interactions), in contrast, the classical annealing dynamics appears to remain stuck in the disordered phase, while we have clear evidence that QA shows a residual energy which decreases towards zero when the total annealing time τ increases, albeit in a rather slow (logarithmic) fashion. This is one of the rare examples where a limited quantum speedup, a speedup by QA over SA, has been shown to exist by direct solutions of the Schrödinger and master equations in combination with a nonequilibrium Landau-Zener analysis. We also analyze the imaginary-time QA dynamics of the model, finding a 1 /τ2 behavior for all finite values of p , as predicted by the adiabatic theorem of quantum mechanics. The Grover-search limit p (odd )=∞ is also discussed.

  14. Goal Directed Model Inversion: Learning Within Domain Constraints (United States)

    Colombano, Silvano P.; Compton, Michael; Raghavan, Bharathi; Lum, Henry, Jr. (Technical Monitor)


    Goal Directed Model Inversion (GDMI) is an algorithm designed to generalize supervised learning to the case where target outputs are not available to the learning system. The output of the learning system becomes the input to some external device or transformation, and only the output of this device or transformation can be compared to a desired target. The fundamental driving mechanism of GDMI is to learn from success. Given that a wrong outcome is achieved, one notes that the action that produced that outcome "would have been right if the outcome had been the desired one." The algorithm makes use of these intermediate "successes" to achieve the final goal. A unique and potentially very important feature of this algorithm is the ability to modify the output of the learning module to force upon it a desired syntactic structure. This differs from ordinary supervised learning in the following way: in supervised learning the exact desired output pattern must be provided. In GDMI instead, it is possible to require simply that the output obey certain rules, i.e., that it "make sense" in some way determined by the knowledge domain. The exact pattern that will achieve the desired outcome is then found by the system. The ability to impose rules while allowing the system to search for its own answers in the context of neural networks is potentially a major breakthrough in two ways: 1) it may allow the construction of networks that can incorporate immediately some important knowledge, i.e. would not need to learn everything from scratch as normally required at present, and 2) learning and searching would be limited to the areas where it is necessary, thus facilitating and speeding up the process. These points are illustrated with examples from robotic path planning and parametric design.

  15. 78 FR 34960 - Airworthiness Directives; Eurocopter France Model Helicopters (United States)


    ... Federal Aviation Administration 14 CFR Part 39 RIN 2120-AA64 Airworthiness Directives; Eurocopter France... rulemaking (NPRM). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter France... economic evaluation, any comments received, and other information. The street address for the Docket...

  16. Expanding the Developmental Models of Writing: A Direct and Indirect Effects Model of Developmental Writing (DIEW) (United States)

    Kim, Young-Suk Grace; Schatschneider, Christopher


    We investigated direct and indirect effects of component skills on writing (DIEW) using data from 193 children in Grade 1. In this model, working memory was hypothesized to be a foundational cognitive ability for language and cognitive skills as well as transcription skills, which, in turn, contribute to writing. Foundational oral language skills…

  17. Direct modeling of regression effects for transition probabilities in the progressive illness-death model

    DEFF Research Database (Denmark)

    Azarang, Leyla; Scheike, Thomas; de Uña-Álvarez, Jacobo


    In this work, we present direct regression analysis for the transition probabilities in the possibly non-Markov progressive illness–death model. The method is based on binomial regression, where the response is the indicator of the occupancy for the given state along time. Randomly weighted score...

  18. Classifiers as a model-free group comparison test. (United States)

    Kim, Bommae; Oertzen, Timo von


    The conventional statistical methods to detect group differences assume correct model specification, including the origin of difference. Researchers should be able to identify a source of group differences and choose a corresponding method. In this paper, we propose a new approach of group comparison without model specification using classification algorithms in machine learning. In this approach, the classification accuracy is evaluated against a binomial distribution using Independent Validation. As an application example, we examined false-positive errors and statistical power of support vector machines to detect group differences in comparison to conventional statistical tests such as t test, Levene's test, K-S test, Fisher's z-transformation, and MANOVA. The SVMs detected group differences regardless of their origins (mean, variance, distribution shape, and covariance), and showed comparably consistent power across conditions. When a group difference originated from a single source, the statistical power of SVMs was lower than the most appropriate conventional test of the study condition; however, the power of SVMs increased when differences originated from multiple sources. Moreover, SVMs showed substantially improved performance with more variables than with fewer variables. Most importantly, SVMs were applicable to any types of data without sophisticated model specification. This study demonstrates a new application of classification algorithms as an alternative or complement to the conventional group comparison test. With the proposed approach, researchers can test two-sample data even when they are not certain which statistical test to use or when data violates the statistical assumptions of conventional methods.

  19. Analysing earthquake slip models with the spatial prediction comparison test

    KAUST Repository

    Zhang, L.


    Earthquake rupture models inferred from inversions of geophysical and/or geodetic data exhibit remarkable variability due to uncertainties in modelling assumptions, the use of different inversion algorithms, or variations in data selection and data processing. A robust statistical comparison of different rupture models obtained for a single earthquake is needed to quantify the intra-event variability, both for benchmark exercises and for real earthquakes. The same approach may be useful to characterize (dis-)similarities in events that are typically grouped into a common class of events (e.g. moderate-size crustal strike-slip earthquakes or tsunamigenic large subduction earthquakes). For this purpose, we examine the performance of the spatial prediction comparison test (SPCT), a statistical test developed to compare spatial (random) fields by means of a chosen loss function that describes an error relation between a 2-D field (‘model’) and a reference model. We implement and calibrate the SPCT approach for a suite of synthetic 2-D slip distributions, generated as spatial random fields with various characteristics, and then apply the method to results of a benchmark inversion exercise with known solution. We find the SPCT to be sensitive to different spatial correlations lengths, and different heterogeneity levels of the slip distributions. The SPCT approach proves to be a simple and effective tool for ranking the slip models with respect to a reference model.

  20. Comparison of high-latitude thermospheric meridionalwinds II: combined FPI, radar and model Climatologies

    Directory of Open Access Journals (Sweden)

    E. M. Griffin


    Full Text Available The climatological behaviour of the thermospheric meridional wind above Kiruna, Sweden (67.4°N, 20.4°E has been investigated for seasonal and solar cycle dependence using six different techniques, comprising both model and experimental sources. Model output from both the empirical Horizontal Wind Model (HWM (Hedin et al., 1988 and the numerical Coupled Thermosphere and Ionosphere Model (CTIM are compared to the measured behaviour at Kiruna, as a single site example. The empirical International Reference Ionosphere (IRI model is used as input to an implementation of servo theory, to provide another climatology combining empirical input with a theoretical framework. The experimental techniques have been introduced in a companion paper in this issue and provide climatologies from direct measurements, using Fabry-Perot Interferometers (FPI, together with 2 separate techniques applied to the European Incoherent Scatter radar (EISCAT database to derive neutral winds. One of these techniques uses the same implementation of servo theory as has been used with the IRI model. Detailed comparisons for each season and solar activity category allow for conclusions to be drawn as to the major influences on the climatological behaviour of the wind at this latitude. Comparison of the incoherent scatter radar (ISR derived neutral winds with FPI, empirical model and numerical model winds is important to our understanding and judgement of the validity of the techniques used to derive thermospheric wind databases. The comparisons also test model performance and indicate possible reasons for differences found between the models. In turn, the conclusions point to possible improvements in their formulation. In particular it is found that the empirical models are over-reliant on mid-latitude data in their formulation, and fail to provide accurate estimates of the winds at high-latitudes.

    Key words. Meteorology and atmospheric dynamics (thermospheric dynamics

  1. Sensitivity of climate models: Comparison of simulated and observed patterns for past climates

    International Nuclear Information System (INIS)

    Prell, W.L.; Webb, T. III.


    Predicting the potential climatic effects of increased concentrations of atmospheric carbon dioxide requires the continuing development of climate models. Confidence in the predictions will be much enhanced once the models are thoroughly tested in terms of their ability to simulate climates that differ significantly from today's climate. As one index of the magnitude of past climate change, the global mean temperature increase during the past 18,000 years is similar to that predicted for carbon dioxide--doubling. Simulating the climatic changes of the past 18,000 years, as well as the warmer-than-present climate of 6000 years ago and the climate of the last interglacial, around 126,000 years ago, provides an excellent opportunity to test the models that are being used in global climate change research. During the past several years, we have used paleoclimatic data to test the accuracy of the National Center for Atmospheric Research, Community Climate Model, Version 0, after changing its boundary conditions to those appropriate for past climates. We have assembled regional and near-global paleoclimatic data sets of pollen, lake level, and marine plankton data and calibrated many of the data in terms of climatic variables. We have also developed methods that permit direct quantitative comparisons between the data and model results. Our research has shown that comparing the model results with the data is an evolutionary process, because the models, the data, and the methods for comparison are continually being improved. During 1992, we have completed new modeling experiments, further analyzed previous model experiments, compiled new paleodata, made new comparisons between data and model results, and participated in workshops on paleoclimatic modeling

  2. A Model-Model and Data-Model Comparison for the Early Eocene Hydrological Cycle (United States)

    Carmichael, Matthew J.; Lunt, Daniel J.; Huber, Matthew; Heinemann, Malte; Kiehl, Jeffrey; LeGrande, Allegra; Loptson, Claire A.; Roberts, Chris D.; Sagoo, Navjit; Shields, Christine


    A range of proxy observations have recently provided constraints on how Earth's hydrological cycle responded to early Eocene climatic changes. However, comparisons of proxy data to general circulation model (GCM) simulated hydrology are limited and inter-model variability remains poorly characterised. In this work, we undertake an intercomparison of GCM-derived precipitation and P - E distributions within the extended EoMIP ensemble (Eocene Modelling Intercomparison Project; Lunt et al., 2012), which includes previously published early Eocene simulations performed using five GCMs differing in boundary conditions, model structure, and precipitation-relevant parameterisation schemes. We show that an intensified hydrological cycle, manifested in enhanced global precipitation and evaporation rates, is simulated for all Eocene simulations relative to the preindustrial conditions. This is primarily due to elevated atmospheric paleo-CO2, resulting in elevated temperatures, although the effects of differences in paleogeography and ice sheets are also important in some models. For a given CO2 level, globally averaged precipitation rates vary widely between models, largely arising from different simulated surface air temperatures. Models with a similar global sensitivity of precipitation rate to temperature (dP=dT ) display different regional precipitation responses for a given temperature change. Regions that are particularly sensitive to model choice include the South Pacific, tropical Africa, and the Peri-Tethys, which may represent targets for future proxy acquisition. A comparison of early and middle Eocene leaf-fossil-derived precipitation estimates with the GCM output illustrates that GCMs generally underestimate precipitation rates at high latitudes, although a possible seasonal bias of the proxies cannot be excluded. Models which warm these regions, either via elevated CO2 or by varying poorly constrained model parameter values, are most successful in simulating a

  3. Comparison of aerodynamic models for Vertical Axis Wind Turbines (United States)

    Simão Ferreira, C.; Aagaard Madsen, H.; Barone, M.; Roscher, B.; Deglaire, P.; Arduin, I.


    Multi-megawatt Vertical Axis Wind Turbines (VAWTs) are experiencing an increased interest for floating offshore applications. However, VAWT development is hindered by the lack of fast, accurate and validated simulation models. This work compares six different numerical models for VAWTS: a multiple streamtube model, a double-multiple streamtube model, the actuator cylinder model, a 2D potential flow panel model, a 3D unsteady lifting line model, and a 2D conformal mapping unsteady vortex model. The comparison covers rotor configurations with two NACA0015 blades, for several tip speed ratios, rotor solidity and fixed pitch angle, included heavily loaded rotors, in inviscid flow. The results show that the streamtube models are inaccurate, and that correct predictions of rotor power and rotor thrust are an effect of error cancellation which only occurs at specific configurations. The other four models, which explicitly model the wake as a system of vorticity, show mostly differences due to the instantaneous or time averaged formulation of the loading and flow, for which further research is needed.

  4. Comparison of Models for Ball Bearing Dynamic Capacity and Life (United States)

    Gupta, Pradeep K.; Oswald, Fred B.; Zaretsky, Erwin V.


    Generalized formulations for dynamic capacity and life of ball bearings, based on the models introduced by Lundberg and Palmgren and Zaretsky, have been developed and implemented in the bearing dynamics computer code, ADORE. Unlike the original Lundberg-Palmgren dynamic capacity equation, where the elastic properties are part of the life constant, the generalized formulations permit variation of elastic properties of the interacting materials. The newly updated Lundberg-Palmgren model allows prediction of life as a function of elastic properties. For elastic properties similar to those of AISI 52100 bearing steel, both the original and updated Lundberg-Palmgren models provide identical results. A comparison between the Lundberg-Palmgren and the Zaretsky models shows that at relatively light loads the Zaretsky model predicts a much higher life than the Lundberg-Palmgren model. As the load increases, the Zaretsky model provides a much faster drop off in life. This is because the Zaretsky model is much more sensitive to load than the Lundberg-Palmgren model. The generalized implementation where all model parameters can be varied provides an effective tool for future model validation and enhancement in bearing life prediction capabilities.

  5. Inter-comparison of experimental catchment data and hydrological modelling (United States)

    Singh, Shailesh Kumar; Ibbitt, Richard; Srinivasan, M. S.; Shankar, Ude


    Hydrological models account for the storage, flow of water and water balance in a catchment, including exchanges of water and energy with the ground, atmosphere and oceans. Because of the need to simplify hydrological models, parameters are often included to help with modelling hydrological processes. Generally the parameters of lumped, semi or distributed hydrological models depend on the values estimated at a gauged location, generally at outlet of the catchment (mostly using discharge). In this approach it is hard to judge how well a model represents internal catchment processes of the hydrological cycle as well as also ignoring the spatial heterogeneity of the catchment. The purpose of the paper is to assess, and potentially improve, the ability of a physically-based semi-distributed hydrological model, TopNet, using a spatially and temporally detailed set of field measurements of catchment responses to diverse weather conditions. The TopNet rainfall-runoff model was applied to the Waipara catchment located in the South Island of New Zealand. Observations from field experiments were compared with the simulation results of uncalibrated TopNet model. The total amount of simulated runoff showed reasonable agreement with observations. However, the model overestimated baseflow and underestimated surface flow. The results show that soil moisture variation within the catchment is well represented by the model. However, comparison of the observed water balance with model results show that there is a deficiency in the calculation of evapotranspiration.

  6. Human Lens Transmission of Blue Light: A Comparison of Autofluorescence-Based and Direct Spectral Transmission Determination

    DEFF Research Database (Denmark)

    Broendsted, Adam Elias; Stormly Hansen, Michael; Lund-Andersen, Henrik


    Purpose: Direct measurement of the transmission of light through the human lens is not possible in vivo unless invasive techniques are used. In the current study, a reliable in vivo estimate of the transmission of blue light through the lens was assessed by comparing an indirect and noninvasive...... method based on autofluorescence measurements with a direct method. Methods: Total transmission of blue light was measured in human donor lenses using a direct method applicable only in vitro and compared with transmittance estimates made by an in vivo applicable autofluorescence technique. Results......: Human lens transmission of blue light decreases with age by 0.7-0.8% per year at 480 nm. The comparison of methods showed that the autofluorescence-based method correlated significantly with the direct measurements (R = 0.83, p

  7. Laser-induced stimulated Raman scattering in the forward direction of a droplet - Comparison of Mie theory with geometrical optics (United States)

    Srivastava, Vandana; Jarzembski, Maurice A.


    This paper uses Mie theory to treat electromagnetic scattering and to evaluate field enhancement in the forward direction of a small droplet irradiated by a high-energy beam and compares the results of calculations with the field-enhancement evaluation obtained via geometrical optics treatment. Results of this comparison suggest that the field enhancement located at the critical ring region encircling the axis in the forward direction of the droplet can support laser-induced Raman scattering. The results are supported by experimental observations of the interaction of a 120-micron-diam water droplet with a high-energy Nd:YAG laser beam.

  8. A predictive model of music preference using pairwise comparisons

    DEFF Research Database (Denmark)

    Jensen, Bjørn Sand; Gallego, Javier Saez; Larsen, Jan


    Music recommendation is an important aspect of many streaming services and multi-media systems, however, it is typically based on so-called collaborative filtering methods. In this paper we consider the recommendation task from a personal viewpoint and examine to which degree music preference can...... be elicited and predicted using simple and robust queries such as pairwise comparisons. We propose to model - and in turn predict - the pairwise music preference using a very flexible model based on Gaussian Process priors for which we describe the required inference. We further propose a specific covariance...

  9. A direct comparison of the sensitivity of CT and MR cardiac perfusion using a myocardial perfusion phantom.


    Otton, James; Morton, Geraint; Schuster, Andreas; Bigalke, Boris; Marano, Riccardo; Olivotti, Luca; Nagel, Eike; Chiribiri, Amedeo


    BACKGROUND: Direct comparison of CT and magnetic resonance (MR) perfusion techniques has been limited and in vivo assessment is affected by physiological variability, timing of image acquisition, and parameter selection. OBJECTIVE: We precisely compared high-resolution k-t SENSE MR cardiac perfusion at 3 T with single-phase CT perfusion (CTP) under identical imaging conditions. METHODS: We used a customized MR imaging and CT compatible dynamic myocardial perfusion phantom to represe...

  10. A comparison of response spectrum and direct integration analysis methods as applied to a nuclear component support structure

    International Nuclear Information System (INIS)

    Bryan, B.J.; Flanders, H.E. Jr.


    Seismic qualification of Class I nuclear components is accomplished using a variety of analytical methods. This paper compares the results of time history dynamic analyses of a heat exchanger support structure using response spectrum and time history direct integration analysis methods. Dynamic analysis is performed on the detailed component models using the two methods. A nonlinear elastic model is used for both the response spectrum and direct integration methods. A nonlinear model which includes friction and nonlinear springs, is analyzed using time history input by direct integration. The loads from the three cases are compared

  11. Panic disorder and agoraphobia: A direct comparison of their multivariate comorbidity patterns. (United States)

    Greene, Ashley L; Eaton, Nicholas R


    Scientific debate has long surrounded whether agoraphobia is a severe consequence of panic disorder or a frequently comorbid diagnosis. Multivariate comorbidity investigations typically treat these diagnoses as fungible in structural models, assuming both are manifestations of the fear-subfactor in the internalizing-externalizing model. No studies have directly compared these disorders' multivariate associations, which could clarify their conceptualization in classification and comorbidity research. In a nationally representative sample (N=43,093), we examined the multivariate comorbidity of panic disorder (1) without agoraphobia, (2) with agoraphobia, and (3) regardless of agoraphobia; and (4) agoraphobia without panic. We conducted exploratory and confirmatory factor analyses of these and 10 other lifetime DSM-IV diagnoses in a nationally representative sample (N=43,093). Differing bivariate and multivariate relations were found. Panic disorder without agoraphobia was largely a distress disorder, related to emotional disorders. Agoraphobia without panic was largely a fear disorder, related to phobias. When considered jointly, concomitant agoraphobia and panic was a fear disorder, and when panic was assessed without regard to agoraphobia (some individuals had agoraphobia while others did not) it was a mixed distress and fear disorder. Diagnoses were obtained from comprehensively trained lay interviewers, not clinicians and analyses used DSM-IV diagnoses (rather than DSM-5). These findings support the conceptualization of agoraphobia as a distinct diagnostic entity and the independent classification of both disorders in DSM-5, suggesting future multivariate comorbidity studies should not assume various panic/agoraphobia diagnoses are invariably fear disorders. Copyright © 2015 Elsevier B.V. All rights reserved.

  12. Cell survival in carbon beams - comparison of amorphous track model predictions

    DEFF Research Database (Denmark)

    Grzanka, L.; Greilich, S.; Korcyl, M.

    distribution models, and gamma response models was developed. This software can be used for direct numerical comparison between the models, submodels and their parameters and experimental data. In the present paper, we look at 10%-survival data from cell lines irradiated in vitro with carbon and proton beams...... neutrons, stopped pions, and heavy ion beams. Nucl Instrum Meth. 1973;111:93-116. 2.Weyrather WK, Kraft G. RBE of carbon ions: experimental data and the strategy of RBE calculation for treatment planning. Radiother Oncol. 2004;73(Suppl 2):161-9. 3.Greilich S, Grzanka L, Bassler N, Andersen CE, Jäkel O...... irradiation. The aim of this paper is to compare the predictions from different amorphous approaches found in the literature - more specifically the phenomenological, analytical model by Katz and co-workers [1] and a Monte-Carlo based full as implemented for example in the local effect model by Scholz et al...

  13. A Comparison of Alternating Current and Direct Current Electrospray Ionization for Mass Spectrometry (United States)

    Sarver, Scott A.; Chetwani, Nishant; Dovichi, Norman J.; Go, David B.; Gartner, Carlos A.


    A series of studies comparing the performance of alternating current electrospray ionization (AC ESI) mass spectrometry (MS) and direct current electrospray ionization (DC ESI) MS have been conducted, exploring the absolute signal intensity and signal-to-background ratios produced by both methods using caffeine and a model peptide as targets. Because the high-voltage AC signal was more susceptible to generating gas discharges, the operating voltage range of AC ESI was significantly smaller than that for DC ESI, such that the absolute signal intensities produced by DC ESI at peak voltages were one to two orders of magnitude greater than those for AC ESI. Using an electronegative nebulizing gas, sulfur hexafluoride (SF6), instead of nitrogen (N2) increased the operating range of AC ESI by ~50 %, but did not appreciably improve signal intensities. While DC ESI generated far greater signal intensities, both ionization methods produced comparable signal-to-background noise, with AC ESI spectra appearing qualitatively cleaner. A quantitative calibration analysis was performed for two analytes, caffeine and the peptide MRFA. AC ESI utilizing SF6 outperforms all other techniques for the detection of MRFA, producing chromatographic limits of detection nearly one order of magnitude lower than that of DC ESI utilizing N2, and one-half that of DC ESI utilizing SF6. However, DC ESI outperforms AC ESI for the analysis of caffeine, indicating that improvements in spectral quality may benefit certain compounds or classes of compounds, on an individual basis.

  14. Performance comparison of hydrological model structures during low flows (United States)

    Staudinger, Maria; Stahl, Kerstin; Tallaksen, Lena M.; Clark, Martyn P.; Seibert, Jan


    Low flows are still poorly reproduced by common hydrological models since they are traditionally designed to meet peak flow situations best possible. As low flow becomes increasingly important to several target areas there is a need to improve available models. We present a study that assesses the impact of model structure on low flow simulations. This is done using the Framework for Understanding Structural Errors (FUSE), which identifies the set of (subjective) decisions made when building a hydrological model, and provides multiple options for each modeling decision. 79 models were built using the FUSE framework, and applied to simulate stream flows in the Narsjø catchment in Norway (119 km²). To allow comparison all new models were calibrated using an automatic optimization method. Low flow and recession analysis of the new models enables us to evaluate model performance focusing on different aspects by using various objective functions. Additionally, model structures responsible for poor performance, and hence unsuitable, can be detected. We focused on elucidating model performance during summer (August - October) and winter low flows which evolve from entirely different hydrological processes in the Narsjø catchment. Summer low flows develop out of a lack of precipitation while winter low flows are due to water storage in ice and snow. The results showed that simulations of summer low flows were throughout poorer than simulations of winter low flows when evaluating with an objective function focusing on low flows; here, the model structure influencing winter low flow simulations is the lower layer architecture. Different model structures were found to influence model performance during the summer season. The choice of other objective functions has the potential to affect such an evaluation. These findings call for the use of different model structures tailored to particular needs.

  15. Comparison Study on Low Energy Physics Model of GEANT4

    International Nuclear Information System (INIS)

    Park, So Hyun; Jung, Won Gyun; Suh, Tae Suk


    The Geant4 simulation toolkit provides improved or renewed physics model according to the version. The latest Geant4.9.3 which has been recoded by developers applies inserted Livermore data and renewed physics model to the low energy electromagnetic physics model. And also, Geant4.9.3 improved the physics factors by modified code. In this study, the stopping power and CSDA(Continuously Slowing Down Approximation) range data of electron or particles were acquired in various material and then, these data were compared with NIST(National Institute of Standards and Technology) data. Through comparison between data of Geant4 simulation and NIST, the improvement of physics model on low energy electromagnetic of Geant4.9.3 was evaluated by comparing the Geant4.9.2

  16. Developing model-making and model-breaking skills using direct measurement video-based activities (United States)

    Vonk, Matthew; Bohacek, Peter; Militello, Cheryl; Iverson, Ellen


    This study focuses on student development of two important laboratory skills in the context of introductory college-level physics. The first skill, which we call model making, is the ability to analyze a phenomenon in a way that produces a quantitative multimodal model. The second skill, which we call model breaking, is the ability to critically evaluate if the behavior of a system is consistent with a given model. This study involved 116 introductory physics students in four different sections, each taught by a different instructor. All of the students within a given class section participated in the same instruction (including labs) with the exception of five activities performed throughout the semester. For those five activities, each class section was split into two groups; one group was scaffolded to focus on model-making skills and the other was scaffolded to focus on model-breaking skills. Both conditions involved direct measurement videos. In some cases, students could vary important experimental parameters within the video like mass, frequency, and tension. Data collected at the end of the semester indicate that students in the model-making treatment group significantly outperformed the other group on the model-making skill despite the fact that both groups shared a common physical lab experience. Likewise, the model-breaking treatment group significantly outperformed the other group on the model-breaking skill. This is important because it shows that direct measurement video-based instruction can help students acquire science-process skills, which are critical for scientists, and which are a key part of current science education approaches such as the Next Generation Science Standards and the Advanced Placement Physics 1 course.

  17. Developing model-making and model-breaking skills using direct measurement video-based activities

    Directory of Open Access Journals (Sweden)

    Matthew Vonk


    Full Text Available This study focuses on student development of two important laboratory skills in the context of introductory college-level physics. The first skill, which we call model making, is the ability to analyze a phenomenon in a way that produces a quantitative multimodal model. The second skill, which we call model breaking, is the ability to critically evaluate if the behavior of a system is consistent with a given model. This study involved 116 introductory physics students in four different sections, each taught by a different instructor. All of the students within a given class section participated in the same instruction (including labs with the exception of five activities performed throughout the semester. For those five activities, each class section was split into two groups; one group was scaffolded to focus on model-making skills and the other was scaffolded to focus on model-breaking skills. Both conditions involved direct measurement videos. In some cases, students could vary important experimental parameters within the video like mass, frequency, and tension. Data collected at the end of the semester indicate that students in the model-making treatment group significantly outperformed the other group on the model-making skill despite the fact that both groups shared a common physical lab experience. Likewise, the model-breaking treatment group significantly outperformed the other group on the model-breaking skill. This is important because it shows that direct measurement video-based instruction can help students acquire science-process skills, which are critical for scientists, and which are a key part of current science education approaches such as the Next Generation Science Standards and the Advanced Placement Physics 1 course.

  18. Comparison of physically based catchment models for estimating Phosphorus losses


    Nasr, Ahmed Elssidig; Bruen, Michael


    As part of a large EPA-funded research project, coordinated by TEAGASC, the Centre for Water Resources Research at UCD reviewed the available distributed physically based catchment models with a potential for use in estimating phosphorous losses for use in implementing the Water Framework Directive. Three models, representative of different levels of approach and complexity, were chosen and were implemented for a number of Irish catchments. This paper reports on (i) the lessons and experience...

  19. Empirical bayes model comparisons for differential methylation analysis. (United States)

    Teng, Mingxiang; Wang, Yadong; Kim, Seongho; Li, Lang; Shen, Changyu; Wang, Guohua; Liu, Yunlong; Huang, Tim H M; Nephew, Kenneth P; Balch, Curt


    A number of empirical Bayes models (each with different statistical distribution assumptions) have now been developed to analyze differential DNA methylation using high-density oligonucleotide tiling arrays. However, it remains unclear which model performs best. For example, for analysis of differentially methylated regions for conservative and functional sequence characteristics (e.g., enrichment of transcription factor-binding sites (TFBSs)), the sensitivity of such analyses, using various empirical Bayes models, remains unclear. In this paper, five empirical Bayes models were constructed, based on either a gamma distribution or a log-normal distribution, for the identification of differential methylated loci and their cell division-(1, 3, and 5) and drug-treatment-(cisplatin) dependent methylation patterns. While differential methylation patterns generated by log-normal models were enriched with numerous TFBSs, we observed almost no TFBS-enriched sequences using gamma assumption models. Statistical and biological results suggest log-normal, rather than gamma, empirical Bayes model distribution to be a highly accurate and precise method for differential methylation microarray analysis. In addition, we presented one of the log-normal models for differential methylation analysis and tested its reproducibility by simulation study. We believe this research to be the first extensive comparison of statistical modeling for the analysis of differential DNA methylation, an important biological phenomenon that precisely regulates gene transcription.

  20. Empirical Bayes Model Comparisons for Differential Methylation Analysis

    Directory of Open Access Journals (Sweden)

    Mingxiang Teng


    Full Text Available A number of empirical Bayes models (each with different statistical distribution assumptions have now been developed to analyze differential DNA methylation using high-density oligonucleotide tiling arrays. However, it remains unclear which model performs best. For example, for analysis of differentially methylated regions for conservative and functional sequence characteristics (e.g., enrichment of transcription factor-binding sites (TFBSs, the sensitivity of such analyses, using various empirical Bayes models, remains unclear. In this paper, five empirical Bayes models were constructed, based on either a gamma distribution or a log-normal distribution, for the identification of differential methylated loci and their cell division—(1, 3, and 5 and drug-treatment-(cisplatin dependent methylation patterns. While differential methylation patterns generated by log-normal models were enriched with numerous TFBSs, we observed almost no TFBS-enriched sequences using gamma assumption models. Statistical and biological results suggest log-normal, rather than gamma, empirical Bayes model distribution to be a highly accurate and precise method for differential methylation microarray analysis. In addition, we presented one of the log-normal models for differential methylation analysis and tested its reproducibility by simulation study. We believe this research to be the first extensive comparison of statistical modeling for the analysis of differential DNA methylation, an important biological phenomenon that precisely regulates gene transcription.

  1. Bayesian inference and model comparison for metallic fatigue data

    KAUST Repository

    Babuška, Ivo


    In this work, we present a statistical treatment of stress-life (S-N) data drawn from a collection of records of fatigue experiments that were performed on 75S-T6 aluminum alloys. Our main objective is to predict the fatigue life of materials by providing a systematic approach to model calibration, model selection and model ranking with reference to S-N data. To this purpose, we consider fatigue-limit models and random fatigue-limit models that are specially designed to allow the treatment of the run-outs (right-censored data). We first fit the models to the data by maximum likelihood methods and estimate the quantiles of the life distribution of the alloy specimen. To assess the robustness of the estimation of the quantile functions, we obtain bootstrap confidence bands by stratified resampling with respect to the cycle ratio. We then compare and rank the models by classical measures of fit based on information criteria. We also consider a Bayesian approach that provides, under the prior distribution of the model parameters selected by the user, their simulation-based posterior distributions. We implement and apply Bayesian model comparison methods, such as Bayes factor ranking and predictive information criteria based on cross-validation techniques under various a priori scenarios.

  2. Comparison of slide agglutination test and direct immunofluorescence assay for identification of Legionella isolates.


    Thacker, W L; Wilkinson, H W; Benson, R F


    It is technically impractical for many clinical laboratories to use the direct immunofluorescence assay for identifying and serogrouping clinical isolates of Legionella. We compared the results obtained with the direct immunofluorescence assay with the results of a simple and less-demanding slide agglutination test for identifying 15 serogroups representing seven Legionella species. The slide agglutination test was in complete agreement with the direct immunofluorescence assay, and the serogr...

  3. On direct hydrogen fuel cell vehicles modelling and demonstration

    Energy Technology Data Exchange (ETDEWEB)

    Haraldsson, Kristina


    In this thesis, direct hydrogen Proton Exchange Membrane (PEM) fuel cell systems in vehicles are investigated through modelling, field tests and public acceptance surveys. A computer model of a 50 kW PEM fuel cell system was developed. The fuel cell system efficiency is approximately 50% between 10 and 45% of the rated power. The fuel cell auxiliary system, e.g. compressor and pumps, was shown to clearly affect the overall fuel cell system electrical efficiency. Two hydrogen on-board storage options, compressed and cryogenic hydrogen, were modelled for the above-mentioned system. Results show that the release of compressed gaseous hydrogen needs approximately 1 kW of heat, which can be managed internally with heat from the fuel cell stack. In the case of cryogenic hydrogen, the estimated heat demand of 13 kW requires an extra heat source. A phase change based (PCM) thermal management solution to keep a 50 kW PEM fuel cell stack warm during dormancy in a cold climate (-20 deg C) was investigated through simulation and experiments. It was shown that a combination of PCM (salt hydrate or paraffin wax) and vacuum insulation materials was able to keep a fuel cell stack from freezing for about three days. This is a simple and potentially inexpensive solution, although development on issues such as weight, volume and encapsulation materials is needed. Two different vehicle platforms, fuel cell vehicles and fuel cell hybrid vehicles, were used to study the fuel consumption and the air, water and heat management of the fuel cell system under varying operating conditions, e.g. duty cycles and ambient conditions. For a compact vehicle, with a 50 kW fuel cell system, the fuel consumption was significantly reduced, {approx}50 %, compared to a gasoline-fuelled vehicle of similar size. A bus with 200 kW fuel cell system was studied and compared to a diesel bus of comparable size. The fuel consumption of the fuel cell bus displayed a reduction of 33-37 %. The performance of a fuel

  4. Comparison of thermodynamic databases used in geochemical modelling

    International Nuclear Information System (INIS)

    Chandratillake, M.R.; Newton, G.W.A.; Robinson, V.J.


    Four thermodynamic databases used by European groups for geochemical modelling have been compared. Thermodynamic data for both aqueous species and solid species have been listed. When the values are directly comparable any differences between them have been highlighted at two levels of significance. (author)

  5. Analyzing and modeling the dynamic thermal behaviors of direct contact condensers packed with PCM spheres (United States)

    Wang, Kai; Hu, Tao; Hassabou, Abdel H.; Spinnler, Markus; Polifke, Wolfgang


    Condensers serve as important components for humidification-dehumidification (HDH) desalination plants. Based on the interpenetration continua approach with volume averaging technique, a mathematical dynamic model for analyzing the heat and mass transfer within direct contact condensers with co-current or countercurrent flow arrangement was developed. It was validated against the experimental data from a small scale HDH desalination system. Comparisons including the productivities and the temperature profiles of gas, liquid, and solid phases show good agreement with the measurements. Phase change material (PCM) melting processes have little effect on water production rate for co-current flow arrangement, but the condenser packed with PCM capsules have higher water production rates than that packed with air capsules packed under given conditions. The relative humidity profile of the bulk gas shows contrary trend with the gas temperature profile. The direct contact condenser with countercurrent flow arrangement can provide much better heat and mass transfer between gas and water and produce about 16.3% more fresh water than the same condenser with co-current flow arrangement in 4 h under given conditions.

  6. mathematical model for direct evaporative space cooling systems

    African Journals Online (AJOL)


    of the sensible heat of the air is transferred to the water and becomes latent heat by evaporating some of the water. The latent heat follows the water vapour and diffuses into the air. In a DEC (direct evaporative cooling), the heat and mass transferred between air and water decreases the air dry bulb temperature (DBT) and ...

  7. Directed Consultation, the SEALS Model, and Teachers' Classroom Management (United States)

    Motoca, Luci M.; Farmer, Thomas W.; Hamm, Jill V.; Byun, Soo-yong; Lee, David L.; Brooks, Debbie S.; Rucker, Nkecha; Moohr, Michele M.


    Directed consultation is presented as a professional development framework to guide and support teachers in the implementation of evidence-based interventions that involve contextual and process-oriented approaches designed to be incorporated into daily classroom management. This approach consists of four components: pre-intervention observations…

  8. Direct Instruction Revisited: A Key Model for Instructional Technology (United States)

    Magliaro, Susan G.; Lockee, Barbara B.; Burton, John K.


    Rooted in behavioral theory, particularly the radical or selectivist behaviorism of B.F. Skinner (1953, 1954, 1966, 1968, 1974), the direct instruction (DI) approach to teaching is now well into its third decade of influencing curriculum, instruction, and research. It is also in its third decade of controversy. Our purpose is to present the DI…

  9. Comparison between the Lactation Model and the Test-Day Model ...

    African Journals Online (AJOL)


    National Genetic Evaluation, using a Fixed Regression Test-day Model (TDM). This comparison is made for. Ayrshire, Guernsey, Holstein and Jersey cows participating in the South African Dairy Animal Improvement. Scheme. Specific differences between the two models were documented, with differences in statistical.

  10. Direct Primary Care in 2015: A Survey with Selected Comparisons to 2005 Survey Data. (United States)

    Rowe, Kyle; Rowe, Whitney; Umbehr, Josh; Dong, Frank; Ablah, Elizabeth


    Direct primary care (DPC), a fee for membership type of practice, is an evolving innovative primary care delivery model. Little is known about current membership fees, insurance billing status, physician training, and patient panel size in DPC practices. This study aimed to obtain current data for these variables, as well as additional demographic and financial indicators, and relate the findings to the Healthy People 2020 goals. It was predicted that DPC practices would (1) submit fewer claims to insurance, (2) have decreased membership fees, (3) be primarily family medicine trained, and (4) have increased the projected patient panel size since 2005. An electronic survey was sent to DPC practices (n = 65) requesting location, membership fees, projected patient panel size, insurance billing status, training, and other demographic and financial indicators. Data were aggregated, reported anonymously, and compared to two prior characterizations of DPC practices done in 2005. Thirty-eight of 65 (59%) practices responded to the 2015 survey. The majority of respondents (84%) reported using an EMR, offering physician email access (82%), 24-hour access (76%), same day appointments (92%), and wholesale labs (74%). Few respondents offered inpatient care (16%), obstetrics (3%), or financial/insurance consultant services. Eighty-eight percent (88%) of practices reported annual individual adult membership rates between $500 and $1,499, decreased from 2005 where 81% reported greater than a $1,500 annual fee. The proportion of practices who submit bills to insurance decreased from 75% in 2005 to 11% in 2015. Fifty-six percent (56%) of practices reported projected patient panel size to be greater than 600, increased from 40% in 2005. Family medicine physicians represented 87% of respondents, markedly different from 2005 when 62 - 77% of DPC respondents were general internal medicine physicians. Most DPC practices no longer submit to insurance and are family medicine trained

  11. Mathematical Modeling of Transport Phenomena in Polymer Electrolyte and Direct Methanol Fuel Cells

    Energy Technology Data Exchange (ETDEWEB)

    Birgersson, Erik


    This thesis deals with modeling of two types of fuel cells: the polymer electrolyte fuel cell (PEFC) and the direct methanol fuel cell (DMFC), for which we address four major issues: a) mass transport limitations; b) water management (PEFC); c) gas management (DMFC); d) thermal management. Four models have been derived and studied for the PEFC, focusing on the cathode. The first exploits the slenderness of the cathode for a two-dimensional geometry, leading to a reduced model, where several non dimensional parameters capture the behavior of the cathode. The model was extended to three dimensions, where four different flow distributors were studied for the cathode. A quantitative comparison shows that the interdigitated channels can sustain the highest current densities. These two models, comprising isothermal gas phase flow, limit the studies to (a). Returning to a two-dimensional geometry of the PEFC, the liquid phase was introduced via a separate flow model approach for the cathode. In addition to conservation of mass, momentum and species, the model was extended to consider simultaneous charge and heat transfer for the whole cell. Different thermal, flow fields, and hydrodynamic conditions were studied, addressing (a), (b) and (d). A scale analysis allowed for predictions of the cell performance prior to any computations. Good agreement between experiments with a segmented cell and the model was obtained. A liquid-phase model, comprising conservation of mass, momentum and species, was derived and analyzed for the anode of the DMFC. The impact of hydrodynamic, electrochemical and geometrical features on the fuel cell performance were studied, mainly focusing on (a). The slenderness of the anode allows the use of a narrow-gap approximation, leading to a reduced model, with benefits such as reduced computational cost and understanding of the physical trends prior to any numerical computations. Adding the gas-phase via a multiphase mixture approach, the gas


    Energy Technology Data Exchange (ETDEWEB)

    Ilkyoung Shin,Byung Yunn,Todd Satogata,Shahid Ahmed


    The transverse focusing effect in RF cavities plays a considerable role in beam dynamics for low-energy beamline sections and can contribute to beam breakup (BBU) instability. The purpose of this analysis is to examine RF cavity models in simulation codes which will be used for BBU experiments at Jefferson Lab and improve BBU simulation results. We review two RF cavity models in the simulation codes elegant and TDBBU (a BBU simulation code developed at Jefferson Lab). elegant can include the Rosenzweig-Serafini (R-S) model for the RF focusing effect. Whereas TDBBU uses a model from the code TRANSPORT which considers the adiabatic damping effect, but not the RF focusing effect. Quantitative comparisons are discussed for the CEBAF beamline. We also compare the R-S model with the results from numerical simulations for a CEBAF-type 5-cell superconducting cavity to validate the use of the R-S model as an improved low-energy RF cavity transport model in TDBBU. We have implemented the R-S model in TDBBU. It will improve BBU simulation results to be more matched with analytic calculations and experimental results.

  13. Comparison Of RF Cavity Transport Models For BBU Simulations

    International Nuclear Information System (INIS)

    Shin, Ilkyoung; Yunn, Byung; Satogata, Todd; Ahmed, Shahid


    The transverse focusing effect in RF cavities plays a considerable role in beam dynamics for low-energy beamline sections and can contribute to beam breakup (BBU) instability. The purpose of this analysis is to examine RF cavity models in simulation codes which will be used for BBU experiments at Jefferson Lab and improve BBU simulation results. We review two RF cavity models in the simulation codes elegant and TDBBU (a BBU simulation code developed at Jefferson Lab). elegant can include the Rosenzweig-Serafini (R-S) model for the RF focusing effect. Whereas TDBBU uses a model from the code TRANSPORT which considers the adiabatic damping effect, but not the RF focusing effect. Quantitative comparisons are discussed for the CEBAF beamline. We also compare the R-S model with the results from numerical simulations for a CEBAF-type 5-cell superconducting cavity to validate the use of the R-S model as an improved low-energy RF cavity transport model in TDBBU. We have implemented the R-S model in TDBBU. It will improve BBU simulation results to be more matched with analytic calculations and experimental results.

  14. A comparison of major petroleum life cycle models | Science ... (United States)

    Many organizations have attempted to develop an accurate well-to-pump life cycle model of petroleum products in order to inform decision makers of the consequences of its use. Our paper studies five of these models, demonstrating the differences in their predictions and attempting to evaluate their data quality. Carbon dioxide well-to-pump emissions for gasoline showed a variation of 35 %, and other pollutants such as ammonia and particulate matter varied up to 100 %. Differences in allocation do not appear to explain differences in predictions. Effects of these deviations on well-to-wheels passenger vehicle and truck transportation life cycle models may be minimal for effects such as global warming potential (6 % spread), but for respiratory effects of criteria pollutants (41 % spread) and other impact categories, they can be significant. A data quality assessment of the models’ documentation revealed real differences between models in temporal and geographic representativeness, completeness, as well as transparency. Stakeholders may need to consider carefully the tradeoffs inherent when selecting a model to conduct life cycle assessments for systems that make heavy use of petroleum products. This is a qualitative and quantitative comparison of petroleum LCA models intended for an expert audience interested in better understanding the data quality of existing petroleum life cycle models and the quantitative differences between these models.

  15. Comparison of models of radionuclide migration in food chains

    International Nuclear Information System (INIS)

    Hanusik, V.; Mitro, A.; Chorvat, D.


    Two models are compared used for describing the transfer of radioactive substances to man through food chains: the model used in US NRC Regulatory Guide 1.109 and that used in Interatomehnergo NTD No. 38.220.56-81. The models are compared with regard to the approach to model construction, with regard to mathematical expressions and recommended values of parameters. The comparative calculations show that with the use of the recommended values the contribution of direct contamination is prevalent in both models. The concentration of radioactive substances in selected products calculated for indirect contamination using the NRC method is more conservative. For direct and total contamination the NRC method provides higher values of concentrations in the leaf and non-leaf vegetables (cabbage, potatoes, cucumbers) than the NTD method. Concentrations in non-leaf vegetables are higher than in wheat for 4 nuclides only and in meat and milk for 13 radionuclides of the considered set of 22 radionuclides. Substitution of the recommended values of the parameters of the NRC model with recommended values of the corresponding parameters of the NTD model will reduce total concentrations in products as against initial results of the two studied models. (author)

  16. Comparison of superconducting generators and permanent magnet generators for 10-MW direct-drive wind turbines

    DEFF Research Database (Denmark)

    Liu, Dong; Polinder, Henk; Abrahamsen, Asger Bech


    Large offshore direct-drive wind turbines of 10-MW power levels are being extensively proposed and studied because of a reduced cost of energy. Conventional permanent magnet generators currently dominating the direct-drive wind turbine market are still under consideration for such large wind...

  17. Comparison of Vector Velocity Imaging using Directional Beamforming and Transverse Oscillation for a Convex Array Transducer

    DEFF Research Database (Denmark)

    Jensen, Jørgen Arendt


    Vector velocity imaging can reveal both the magnitude and direction of the blood velocity. Several techniques have been suggested for estimating the velocity, and this paper compares the performance for directional beamforming and transverse oscillation (TO) vector flow imaging (VFI). Data have b...

  18. Modeling trans-spinal direct current stimulation for the modulation of the lumbar spinal motor pathways (United States)

    Kuck, A.; Stegeman, D. F.; van Asseldonk, E. H. F.


    Objective. Trans-spinal direct current stimulation (tsDCS) is a potential new technique for the treatment of spinal cord injury (SCI). TsDCS aims to facilitate plastic changes in the neural pathways of the spinal cord with a positive effect on SCI recovery. To establish tsDCS as a possible treatment option for SCI, it is essential to gain a better understanding of its cause and effects. We seek to understand the acute effect of tsDCS, including the generated electric field (EF) and its polarization effect on the spinal circuits, to determine a cellular target. We further ask how these findings can be interpreted to explain published experimental results. Approach. We use a realistic full body finite element volume conductor model to calculate the EF of a 2.5 mA direct current for three different electrode configurations. We apply the calculated electric field to realistic motoneuron models to investigate static changes in membrane resting potential. The results are combined with existing knowledge about the theoretical effect on a neuronal level and implemented into an existing lumbar spinal network model to simulate the resulting changes on a network level. Main results. Across electrode configurations, the maximum EF inside the spinal cord ranged from 0.47 V m-1 to 0.82 V m-1. Axon terminal polarization was identified to be the dominant cellular target. Also, differences in electrode placement have a large influence on axon terminal polarization. Comparison between the simulated acute effects and the electrophysiological long-term changes observed in human tsDCS studies suggest an inverse relationship between the two. Significance. We provide methods and knowledge for better understanding the effects of tsDCS and serve as a basis for a more targeted and optimized application of tsDCS.

  19. Comparisons of Faulting-Based Pavement Performance Prediction Models

    Directory of Open Access Journals (Sweden)

    Weina Wang


    Full Text Available Faulting prediction is the core of concrete pavement maintenance and design. Highway agencies are always faced with the problem of lower accuracy for the prediction which causes costly maintenance. Although many researchers have developed some performance prediction models, the accuracy of prediction has remained a challenge. This paper reviews performance prediction models and JPCP faulting models that have been used in past research. Then three models including multivariate nonlinear regression (MNLR model, artificial neural network (ANN model, and Markov Chain (MC model are tested and compared using a set of actual pavement survey data taken on interstate highway with varying design features, traffic, and climate data. It is found that MNLR model needs further recalibration, while the ANN model needs more data for training the network. MC model seems a good tool for pavement performance prediction when the data is limited, but it is based on visual inspections and not explicitly related to quantitative physical parameters. This paper then suggests that the further direction for developing the performance prediction model is incorporating the advantages and disadvantages of different models to obtain better accuracy.

  20. Comparison of "Direct" and "Indirect" Nuclear Cystography in the Diagnosis of Vesicoureteric Reflux

    Directory of Open Access Journals (Sweden)

    Khriesat Imad


    Full Text Available This study was undertaken to compare "direct" and "indirect" nuclear cystography for the detection of vesicoureteral reflux (VUR. Forty-five children (15 males and 30 females, ranging in age from 5 months to 10 years, were studied at the King Hussein Medical Center, Amman, Jordan between January 1998 and December 1999, using both direct (catheter and indirect techniques of nuclear cystography (NC. Of the 82 ureters that could be compared, 32 ureters were positive for VUR on the direct technique while only 20 ureters showed VUR on the indirect technique (sensitivity 62%. Nine ureters, which did not show VUR on the direct cystogram, were read as positive on the indirect cystogram (specificity 82%. The false positive results of indirect nuclear cystogram make it invalid for VUR screening program, while the ease of assessment and low radiation dose from the direct NC has made this the recommended test for screening and follow-up of VUR.

  1. Luttinger model the first 50 years and some new directions

    CERN Document Server

    Mattis, Daniel C


    The Luttinger Model is the only model of many-fermion physics with legitimate claims to be both exactly and completely solvable. In several respects it plays the same role in many-body theory as does the 2D Ising model in statistical physics. Interest in the Luttinger model has increased steadily ever since its introduction half a century ago. The present volume starts with reprints of the seminal papers in which it was originally introduced and solved, and continues with several contributions setting out the landscape of the principal advances of the last fifty years and of prominent new dire

  2. Comparing Apples to Apples: Paleoclimate Model-Data comparison via Proxy System Modeling (United States)

    Dee, Sylvia; Emile-Geay, Julien; Evans, Michael; Noone, David


    The wealth of paleodata spanning the last millennium (hereinafter LM) provides an invaluable testbed for CMIP5-class GCMs. However, comparing GCM output to paleodata is non-trivial. High-resolution paleoclimate proxies generally contain a multivariate and non-linear response to regional climate forcing. Disentangling the multivariate environmental influences on proxies like corals, speleothems, and trees can be complex due to spatiotemporal climate variability, non-stationarity, and threshold dependence. Given these and other complications, many paleodata-GCM comparisons take a leap of faith, relating climate fields (e.g. precipitation, temperature) to geochemical signals in proxy data (e.g. δ18O in coral aragonite or ice cores) (e.g. Braconnot et al., 2012). Isotope-enabled GCMs are a step in the right direction, with water isotopes providing a connector point between GCMs and paleodata. However, such studies are still rare, and isotope fields are not archived as part of LM PMIP3 simulations. More importantly, much of the complexity in how proxy systems record and transduce environmental signals remains unaccounted for. In this study we use proxy system models (PSMs, Evans et al., 2013) to bridge this conceptual gap. A PSM mathematically encodes the mechanistic understanding of the physical, geochemical and, sometimes biological influences on each proxy. To translate GCM output to proxy space, we have synthesized a comprehensive, consistently formatted package of published PSMs, including δ18O in corals, tree ring cellulose, speleothems, and ice cores. Each PSM is comprised of three sub-models: sensor, archive, and observation. For the first time, these different components are coupled together for four major proxy types, allowing uncertainties due to both dating and signal interpretation to be treated within a self-consistent framework. The output of this process is an ensemble of many (say N = 1,000) realizations of the proxy network, all equally plausible

  3. Transcranial direct current stimulation of right dorsolateral prefrontal cortex does not affect model-based or model-free reinforcement learning in humans. (United States)

    Smittenaar, Peter; Prichard, George; FitzGerald, Thomas H B; Diedrichsen, Joern; Dolan, Raymond J


    There is broad consensus that the prefrontal cortex supports goal-directed, model-based decision-making. Consistent with this, we have recently shown that model-based control can be impaired through transcranial magnetic stimulation of right dorsolateral prefrontal cortex in humans. We hypothesized that an enhancement of model-based control might be achieved by anodal transcranial direct current stimulation of the same region. We tested 22 healthy adult human participants in a within-subject, double-blind design in which participants were given Active or Sham stimulation over two sessions. We show Active stimulation had no effect on model-based control or on model-free ('habitual') control compared to Sham stimulation. These null effects are substantiated by a power analysis, which suggests that our study had at least 60% power to detect a true effect, and by a Bayesian model comparison, which favors a model of the data that assumes stimulation had no effect over models that assume stimulation had an effect on behavioral control. Although we cannot entirely exclude more trivial explanations for our null effect, for example related to (faults in) our experimental setup, these data suggest that anodal transcranial direct current stimulation over right dorsolateral prefrontal cortex does not improve model-based control, despite existing evidence that transcranial magnetic stimulation can disrupt such control in the same brain region.

  4. The cosmological Janus model: comparison with observational data (United States)

    Petit, Jean-Pierre; Dagostini, Gilles


    In 2014 we presented a model based on a system of two coupled field equations to describe two populations of particles, one positive and the other mass of negative mass. The analysis of this system by Newtonian approximation show that the masses of the same signs attract according to Newton's law while the masses of opposite signs repel according to an anti-Newton law. This eliminates the runaway phenomenon. It uses the time-dependent exact solution of this system to build the bolometric magnitude distribution of the red-shift. Comparing the prediction of our model -which requires adjustment with a single parameter- with the data from 740 supernovae highlighting the acceleration of the universe gives an excellent agreement. The comparison is then made with the multi-parametric Λ CDM model.

  5. The Scaling of Paired Comparison Data with One or More Extreme Stimuli: A Comparison of Three Models (United States)

    Wild, Bradford S.; Cabral, Robert M.


    Two models for scaling of paired comparison data are compared to the Thurstone case III model. Two goodness of fit indices are presented for each model for five data sets. The results illustrate the inability of the Thurstone model to adequately account for data when the scale includes extreme stimuli. (Author)


    NARCIS (Netherlands)

    BULT, [No Value

    In this paper we are concerned with estimation of a classification model using semiparametric and parametric methods. Benefits and limitations of semiparametric models in general, and of Manski's maximum score method in particular, are discussed. The maximum score method yields consistent estimates

  7. Modeling the Movement of Beach Alluvia in the Alongshore Direction

    Directory of Open Access Journals (Sweden)

    Elena V. Bondareva


    Full Text Available The authors have worked out a design model for the dynamics of a mixed-composition beach in the vicinity of transverse structures. The model uses a modified formula for calculating alluvia, which is based on modified energy dependencies. The authors provide an algorithm for performing these calculations.

  8. Parallel direct solver for finite element modeling of manufacturing processes

    DEFF Research Database (Denmark)

    Nielsen, Chris Valentin; Martins, P.A.F.


    The central processing unit (CPU) time is of paramount importance in finite element modeling of manufacturing processes. Because the most significant part of the CPU time is consumed in solving the main system of equations resulting from finite element assemblies, different approaches have been...... developed to optimize solutions and reduce the overall computational costs of large finite element models....

  9. Mathematical Model for Direct Evaporative Space Cooling Systems ...

    African Journals Online (AJOL)

    This paper deals with the development of a simple mathematical model for experimental validation of the performance of a small evaporative cooling system in a tropical climate. It also presents the coefficient of convective heat transfer of wide range of temperatures based on existing model. Extensive experiments have ...

  10. Zr Extrusion – Direct Input for Models & Validation

    Energy Technology Data Exchange (ETDEWEB)

    Cerreta, Ellen Kathleen [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)


    As we examine differences in the high strain rate, high strain tensile response of high purity, highly textured Zr as a function of loading direction, temperature and extrusion velocity with primarily post mortem characterization techniques, we have also developed a technique for characterizing the in-situ extrusion process. This particular measurement is useful for partitioning energy of the system during the extrusion process: friction, kinetic energy, and temperature

  11. Numerical implementation of a model with directional distortional hardening

    Czech Academy of Sciences Publication Activity Database

    Marek, René; Plešek, Jiří; Hrubý, Zbyněk; Parma, Slavomír; Feigenbaum, H. P.; Dafalias, Y.F.


    Roč. 141, č. 12 (2015), 04015048-04015048 ISSN 0733-9399 R&D Projects: GA MŠk LH14018; GA ČR(CZ) GA15-20666S Institutional support: RVO:61388998 Keywords : plasticity * directional distortional hardening * finite-element procedures Subject RIV: JG - Metallurgy Impact factor: 1.346, year: 2015

  12. Comparison of superconducting generators and permanent magnet generators for 10-MW direct-drive wind turbines

    DEFF Research Database (Denmark)

    Liu, Dong; Polinder, Henk; Abrahamsen, Asger Bech


    Large offshore direct-drive wind turbines of 10-MW power levels are being extensively proposed and studied because of a reduced cost of energy. Conventional permanent magnet generators currently dominating the direct-drive wind turbine market are still under consideration for such large wind...... turbines. In the meantime, superconducting generators (SCSGs) have been of particular interest to become a significant competitor because of their compactness and light weight. This paper compares the performance indicators of these two direct-drive generator types in the same 10-MW wind turbine under...

  13. Comparison of direct and indirect plasma oxidation of NO combined with oxidation by catalyst

    DEFF Research Database (Denmark)

    Jogi, Indrek; Stamate, Eugen; Irimiea, Cornelia


    Direct and indirect plasma oxidation of NOx was tested in a medium-scale test-bench at gas flows of 50 slm (3 m(3)/h). For direct plasma oxidation the synthetic flue gas was directed through a stacked DBD reactor. For indirect plasma oxidation, a DBD reactor was used to generate ozone from pure O-2...... and the plasma treated gas including ozone was mixed with flue gas at the entrance of a 6 m long serpentine-like reaction chamber which allowed reaction times longer than 10 s. At relatively low NOx concentrations of 200 ppm, both oxidation methods gave similar results. However, the temperature increase...

  14. Individual based and mean-field modeling of direct aggregation

    KAUST Repository

    Burger, Martin


    We introduce two models of biological aggregation, based on randomly moving particles with individual stochasticity depending on the perceived average population density in their neighborhood. In the firstorder model the location of each individual is subject to a density-dependent random walk, while in the second-order model the density-dependent random walk acts on the velocity variable, together with a density-dependent damping term. The main novelty of our models is that we do not assume any explicit aggregative force acting on the individuals; instead, aggregation is obtained exclusively by reducing the individual stochasticity in response to higher perceived density. We formally derive the corresponding mean-field limits, leading to nonlocal degenerate diffusions. Then, we carry out the mathematical analysis of the first-order model, in particular, we prove the existence of weak solutions and show that it allows for measure-valued steady states. We also perform linear stability analysis and identify conditions for pattern formation. Moreover, we discuss the role of the nonlocality for well-posedness of the first-order model. Finally, we present results of numerical simulations for both the first- and second-order model on the individual-based and continuum levels of description. 2012 Elsevier B.V. All rights reserved.

  15. 76 FR 56637 - Airworthiness Directives; Lycoming Engines Model IO-720-A1B Reciprocating Engines (United States)


    ... Airworthiness Directives; Lycoming Engines Model IO-720-A1B Reciprocating Engines AGENCY: Federal Aviation... directive (AD) for certain model IO-720-A1B Lycoming Engines reciprocating engines. This AD requires a... two Lycoming Engines model IO- 720-A1B reciprocating engines, installed on airplanes of U.S. registry...

  16. A randomized comparison of Verres needle and direct trocar insertion for laparoscopy. (United States)

    Byron, J W; Markenson, G; Miyazawa, K


    Two hundred and fifty-two women scheduled to undergo laparoscopy were randomly assigned to a Verres needle or direct insertion group. The groups were similar with respect to incidence of obesity, prior surgical treatment, indication for operation and level of training of the surgeon performing the procedure. There were no major complications associated with either technique. Minor complications (preperitoneal insufflation, failed entry or more than three attempts necessary to enter the peritoneal cavity with the trocar) were significantly more frequent (p Verres needle technique group. One hundred and thirteen of these patients underwent sterilization procedures. The mean times for performance of the laparoscopic procedure using the direct insertion and Verres needle techniques was 15.3 and 19.6 minutes, respectively. The time saved using the direct insertion technique is explained by a significant (p Verres needle techniques, respectively. We prefer the direct insertion technique for trocar placement because it has fewer minor complications and requires less operating time.

  17. Direct comparison of enzyme histochemical and immunohistochemical methods to localize an enzyme

    NARCIS (Netherlands)

    van Noorden, Cornelis J. F.


    Immunohistochemical localization of enzymes is compared directly with localization of enzyme activity with (catalytic) enzyme histochemical methods. The two approaches demonstrate principally different aspects of an enzyme. The immunohistochemical method localizes the enzyme protein whether it is

  18. Effectiveness comparison of inferior alveolar nerve block anesthesia using direct and indirect technique

    Directory of Open Access Journals (Sweden)

    Rehatta Yongki


    Full Text Available Local anesthesia is important to do prior to tooth extraction procedure to control the patient's pain. Local anesthetic technique in dentistry consists of topical, infiltration, and anesthetic blocks. For molar tooth extraction, mandibular block technique is used either direct or indirect. This study aimed to see if there are differences in effectiveness of inferior alveolar nerve block anesthesia techniques between direct and indirect. This clinical experimental design study used 20 patients as samples during February-April. 10 patients were taken as a group that carried out direct technique while 10 others group conducted indirect techniques. The sample selection using purposive sampling method. Pain level were measured using objective assessments (pain experienced by the patient after a given stimulus and subjective evaluation (thick taste perceived by the patient. The average time of onset in direct and indirect techniques in each sample was 16.88 ± 5.30 and 102.00 ± 19.56 seconds (subjectively and 22.50 ± 8.02 and 159.00 ± 25.10 (objectively. These results indicated direct techniques onset faster than indirect techniques. The average duration of direct and indirect techniques respectively was 121.63 ± 8.80 and 87.80 ± 9.96 minutes (subjectively and 91.88 ± 8.37 and 60.20 ± 10.40 minutes (objectively. These results indicated the duration of direct technique is longer than indirect technique. There was no significant difference when viewed from anesthesia depth and aspiration level. This study indicated that direct technique had better effect than indirect technique in terms of onset and duration, while in terms of anesthesia depth and aspiration level was relatively equal. Insignificant differences were obtained when assessing anesthetic technique successful rate based on gender, age and extracted tooth.

  19. The Tripartite Influence model of body image and eating disturbance: a covariance structure modeling investigation testing the mediational role of appearance comparison. (United States)

    van den Berg, Patricia; Thompson, J Kevin; Obremski-Brandon, Karen; Coovert, Michael


    Recent theoretical approaches to the etiology of eating disorders and body image disturbances have begun to focus on multifactorial models. In the current study, the Tripartite Influence model was examined in a large sample of college females (ages 18-22). This model proposes that three primary core sources of influence--parents, peers and media--contribute to the development of body image and eating disturbances. Additionally, the model suggests that at least two factors mediate the relationship between influences and disturbance-appearance comparison and internalization of media information. In this study, appearance comparison was examined as a mediational link between peer, family and media influence variables and the outcome disturbance measures of eating dysfunction and body image dissatisfaction. Covariance structure modeling (CSM) was used to test the proposed pathways. The results indicated that appearance comparison mediated the effects of family and media influences on body dissatisfaction, which in turn influenced restrictive and bulimic behaviors. In addition, peer influences had a direct influence on restriction. Perfectionism was hypothesized to relate to body dissatisfaction, but was in fact found to influence appearance comparison. The findings were limited by the necessity of several modifications to the originally proposed models, yet offer replication and extension of previous work with appearance comparison and support for further testing of the Tripartite Influence model. Copyright 2002 Elsevier Science Inc.

  20. Thermodynamic modeling of direct injection methanol fueled engines

    International Nuclear Information System (INIS)

    Shen Yuan; Bedford, Joshua; Wichman, Indrek S.


    In-cylinder pressure is an important parameter that is used to investigate the combustion process in internal combustion (IC) engines. In this paper, a thermodynamic model of IC engine combustion is presented and examined. A heat release function and an empirical conversion efficiency factor are introduced to solve the model. The pressure traces obtained by solving the thermodynamic model are compared with measured pressure data for a fully instrumented laboratory IC spark ignition (SI) engine. Derived scaling parameters for time to peak pressure, peak pressure, and maximum rate of pressure rise (among others) are developed and compared with the numerical simulations. The models examined here may serve as pedagogic tools and, when suitably refined, as preliminary design tools.

  1. The Integrated Landscape Modeling partnership - Current status and future directions (United States)

    Mushet, David M.; Scherff, Eric J.


    The Integrated Landscape Modeling (ILM) partnership is an effort by the U.S. Geological Survey (USGS) and U.S. Department of Agriculture (USDA) to identify, evaluate, and develop models to quantify services derived from ecosystems, with a focus on wetland ecosystems and conservation effects. The ILM partnership uses the Integrated Valuation of Ecosystem Services and Tradeoffs (InVEST) modeling platform to facilitate regional quantifications of ecosystem services under various scenarios of land-cover change that are representative of differing conservation program and practice implementation scenarios. To date, the ILM InVEST partnership has resulted in capabilities to quantify carbon stores, amphibian habitat, plant-community diversity, and pollination services. Work to include waterfowl and grassland bird habitat quality is in progress. Initial InVEST modeling has been focused on the Prairie Pothole Region (PPR) of the United States; future efforts might encompass other regions as data availability and knowledge increase as to how functions affecting ecosystem services differ among regions.The ILM partnership is also developing the capability for field-scale process-based modeling of depressional wetland ecosystems using the Agricultural Policy/Environmental Extender (APEX) model. Progress was made towards the development of techniques to use the APEX model for closed-basin depressional wetlands of the PPR, in addition to the open systems that the model was originally designed to simulate. The ILM partnership has matured to the stage where effects of conservation programs and practices on multiple ecosystem services can now be simulated in selected areas. Future work might include the continued development of modeling capabilities, as well as development and evaluation of differing conservation program and practice scenarios of interest to partner agencies including the USDA’s Farm Service Agency (FSA) and Natural Resources Conservation Service (NRCS). When

  2. Slow electron energy balance for hybrid models of direct-current glow discharges (United States)

    Eliseev, S. I.; Bogdanov, E. A.; Kudryavtsev, A. A.


    In this paper, we present the formulation of slow electron energy balance for hybrid models of direct current (DC) glow discharge. Electrons originating from non-local ionization (secondary) contribute significantly to the energy balance of slow electrons. An approach towards calculating effective energy brought by a secondary electron to the group of slow electrons by means of Coulomb collisions is suggested. The value of effective energy shows a considerable dependence on external parameters of a discharge, such as gas pressure, type, and geometric parameters. The slow electron energy balance was implemented into a simple hybrid model that uses analytical formulation for the description of non-local ionization by fast electrons. Simulations of short (without positive column) DC glow discharge in argon are carried out for a range of gas pressures. Comparison with experimental data showed generally good agreement in terms of current-voltage characteristics, electron density, and electron temperature. Simulations also capture the trend of increasing electron density with decreasing pressure observed in the experiment. Analysis shows that for considered conditions, the product of maximum electron density ne and electron temperature Te in negative glow is independent of gas pressure and depends on the gas type, cathode material, and discharge current. Decreasing gas pressure reduces the heating rate of slow electrons during Coulomb collisions with secondary electrons, which leads to lower values of Te and, in turn, higher maximum ne.

  3. Direct simulation Monte Carlo modeling of relaxation processes in polyatomic gases (United States)

    Pfeiffer, M.; Nizenkov, P.; Mirza, A.; Fasoulas, S.


    Relaxation processes of polyatomic molecules are modeled and implemented in an in-house Direct Simulation Monte Carlo code in order to enable the simulation of atmospheric entry maneuvers at Mars and Saturn's Titan. The description of rotational and vibrational relaxation processes is derived from basic quantum-mechanics using a rigid rotator and a simple harmonic oscillator, respectively. Strategies regarding the vibrational relaxation process are investigated, where good agreement for the relaxation time according to the Landau-Teller expression is found for both methods, the established prohibiting double relaxation method and the new proposed multi-mode relaxation. Differences and applications areas of these two methods are discussed. Consequently, two numerical methods used for sampling of energy values from multi-dimensional distribution functions are compared. The proposed random-walk Metropolis algorithm enables the efficient treatment of multiple vibrational modes within a time step with reasonable computational effort. The implemented model is verified and validated by means of simple reservoir simulations and the comparison to experimental measurements of a hypersonic, carbon-dioxide flow around a flat-faced cylinder.

  4. Direct adaptive feedforward compensation of narrowband disturbances without explicit identification of the secondary path model (United States)

    Zech, Philipp; Lato, Victorio; Rinderknecht, Stephan


    The effectiveness of common algorithms for feedforward compensation of narrowband disturbance depends mainly on the model quality. To avoid this dependency several direct adaptive control algorithms without explicitly identified secondary path models have been developed over the last years. However an overview of their properties and a comparison of their performances in a standardized benchmark is still lacking. In this paper the three most promising algorithms are modified for narrowband feedforward vibration control for the use in rotating machinery. As in this application the reference signal is generated using the frequency measurement from a speed sensor it can be assumed that there is no coupling between reference measurement and the secondary path. First the algorithms are tested in simulation, then they are implemented on a test rig for active vibration control of unbalance induced rotor vibration. In simulation as well as for the test rig the performances of the algorithms are compared to each other. Advantages and drawbacks of the algorithms are discussed and practical instructions for implementation are given. The work is intended to serve as starting point and motivation for future research in this field of study.

  5. Lexical ambiguity resolution for Turkish in direct transfer machine translation models


    Tantuğ, A. Cüneyd; Tantug, A. Cuneyd; Oflazer, Kemal; Adalı, Eşref; Adali, Esref


    This paper presents a statistical lexical ambiguity resolution method in direct transfer machine translation models in which the target language is Turkish. Since direct transfer MT models do not have full syntactic information, most of the lexical ambiguity resolution methods are not very helpful. Our disambiguation model is based on statistical language models. We have investigated the performances of some statistical language model types and parameters in lexical ambiguity resolution for o...

  6. Comparison of the models of financial distress prediction

    Directory of Open Access Journals (Sweden)

    Jiří Omelka


    Full Text Available Prediction of the financial distress is generally supposed as approximation if a business entity is closed on bankruptcy or at least on serious financial problems. Financial distress is defined as such a situation when a company is not able to satisfy its liabilities in any forms, or when its liabilities are higher than its assets. Classification of financial situation of business entities represents a multidisciplinary scientific issue that uses not only the economic theoretical bases but interacts to the statistical, respectively to econometric approaches as well.The first models of financial distress prediction have originated in the sixties of the 20th century. One of the most known is the Altman’s model followed by a range of others which are constructed on more or less conformable bases. In many existing models it is possible to find common elements which could be marked as elementary indicators of potential financial distress of a company. The objective of this article is, based on the comparison of existing models of prediction of financial distress, to define the set of basic indicators of company’s financial distress at conjoined identification of their critical aspects. The sample defined this way will be a background for future research focused on determination of one-dimensional model of financial distress prediction which would subsequently become a basis for construction of multi-dimensional prediction model.

  7. Developing the Self-Directed Learning Instructional Model to Enhance English Reading Ability and Self-Directed Learning of Undergraduate Students (United States)

    Wichadee, Saovapa


    The purposes of this study were to develop the instructional model for enhancing self-directed learning skills of Bangkok University students, study the impacts of the model on their English reading comprehension and self-directed learning ability as well as explore their opinion towards self-directed learning. The model development process…

  8. Comparison of Rice Direct Seeding Methods (Mechanical and Manual with Transplanting Method

    Directory of Open Access Journals (Sweden)

    A Eyvani


    Full Text Available The main method of rice planting in Iran is transplanting. Due to poor mechanization of rice production, this method is laborious and costly. The other method is direct seeding in wet lands which is performed in the one third of rice cultivation area of the world. The most important problem in this method is high labor requirement of weed control. In order to compare the different rice planting methods (direct drilling, transplanting, and seed broadcasting a manually operated rice direct seeder (drum seeder was designed and fabricated. The research was conducted using a randomized complete block design with three treatments and three replications. Required draft force, field efficiency, effective field capacity, yield, and yield components were measured and the treatments were compared economically. Results showed that there were significant differences among the treatments from the view point of rice yield at the confidence level of 95% i.e. the transplanting method had the maximum yield. A higher rice yield was obtained from the direct seeder compared to the manual broadcasting method but, the difference between these two methods for crop yield was not significant even at the confidence level of the 95%. The coefficient of variation of seed distribution with direct seeding was more than 20%. The labor and time requirements per hectare reduced to 7 and 20 times, respectively when comparing the newly designed direct seeder with the transplanting method. The direct seeding method had the highest benefit to cost ratio in spite of its lower yield. Therefore, this method could be recommended in the rice growing regions.

  9. Investigating the performance of directional boundary layer model through staged modeling method (United States)

    Jeong, Moon-Gyu; Lee, Won-Chan; Yang, Seung-Hune; Jang, Sung-Hoon; Shim, Seong-Bo; Kim, Young-Chang; Suh, Chun-Suk; Choi, Seong-Woon; Kim, Young-Hee


    BLM since the feasibility of the BLM has been investigated in many papers[4][5][6]. Instead of fitting the parameters to the wafer critical dimensions (CD) directly, we tried to use the aerial image (AI) from the rigorous simulator with the electromagnetic field (EMF) solver. Usually that kind of method is known as the staged modeling method. To see the advantages of this method we conducted several experiments and observed the results comparing the method of fitting to the wafer CD directly. Through the tests we could observe some remarkable results and confirmed that the staged modeling had better performance in many ways.

  10. Comparison of measurement models based on expectations and perceived performance for the satisfaction study in health services

    Directory of Open Access Journals (Sweden)

    Diana E. Forero


    Full Text Available The literature on satisfaction measurement features several models for establishing the relationship between expectations, service performance and satisfaction. The set of measures used includes the Importance-Performance Analysis (IPA, expectation disconfirmation and the satisfaction determinants model. This paper presents a comparison of different measurement models on the basis of a sample of 2900 health services users. The comparison shows that the expectations disconfirmation model allows to establish significant correlations between service attributes and general satisfaction, yet it warrants an adjustment of data distribution to identify the attributes where confirmation and disconfirmation are presented – when not due to chance. On the other hand, the direct effect approach allows to identify predictor attributes of satisfaction better than the other models do, whereas the importance – performance model is easier to implement but can generate erroneous conclusions about the service attributes that generate satisfaction.

  11. Comparison of evolutionary algorithms in gene regulatory network model inference.

    LENUS (Irish Health Repository)


    ABSTRACT: BACKGROUND: The evolution of high throughput technologies that measure gene expression levels has created a data base for inferring GRNs (a process also known as reverse engineering of GRNs). However, the nature of these data has made this process very difficult. At the moment, several methods of discovering qualitative causal relationships between genes with high accuracy from microarray data exist, but large scale quantitative analysis on real biological datasets cannot be performed, to date, as existing approaches are not suitable for real microarray data which are noisy and insufficient. RESULTS: This paper performs an analysis of several existing evolutionary algorithms for quantitative gene regulatory network modelling. The aim is to present the techniques used and offer a comprehensive comparison of approaches, under a common framework. Algorithms are applied to both synthetic and real gene expression data from DNA microarrays, and ability to reproduce biological behaviour, scalability and robustness to noise are assessed and compared. CONCLUSIONS: Presented is a comparison framework for assessment of evolutionary algorithms, used to infer gene regulatory networks. Promising methods are identified and a platform for development of appropriate model formalisms is established.

  12. Comparison of different approaches of modelling in a masonry building (United States)

    Saba, M.; Meloni, D.


    The present work has the objective to model a simple masonry building, through two different modelling methods in order to assess their validity in terms of evaluation of static stresses. Have been chosen two of the most commercial software used to address this kind of problem, which are of S.T.A. Data S.r.l. and Sismicad12 of Concrete S.r.l. While the 3Muri software adopts the Frame by Macro Elements Method (FME), which should be more schematic and more efficient, Sismicad12 software uses the Finite Element Method (FEM), which guarantees accurate results, with greater computational burden. Remarkably differences of the static stresses, for such a simple structure between the two approaches have been found, and an interesting comparison and analysis of the reasons is proposed.

  13. Model/data comparison of typhoon-generated noise

    International Nuclear Information System (INIS)

    Wang Jing-Yan; Li Feng-Hua


    Ocean noise recorded during a typhoon can be used to monitor the typhoon and investigate the mechanism of the wind-generated noise. An analytical expression for the typhoon-generated noise intensity is derived as a function of wind speed. A “bi-peak” structure was observed in an experiment during which typhoon-generated noise was recorded. Wind speed dependence and frequency dependence were also observed in the frequency range of 100 Hz–1000 Hz. The model/data comparison shows that results of the present model of 500 Hz and 1000 Hz are in reasonable agreement with the experimental data, and the typhoon-generated noise intensity has a dependence on frequency and a power-law dependence on wind speed. (special topic)

  14. Comparison of particular logistic models' adoption in the Czech Republic (United States)

    Vrbová, Petra; Cempírek, Václav


    Managing inventory is considered as one of the most challenging tasks facing supply chain managers and specialists. Decisions related to inventory locations along with level of inventory kept throughout the supply chain have a fundamental impact on the response time, service level, delivery lead-time and the total cost of the supply chain. The main objective of this paper is to identify and analyse the share of a particular logistic model adopted in the Czech Republic (Consignment stock, Buffer stock, Safety stock) and also compare their usage and adoption according to different industries. This paper also aims to specify possible reasons of particular logistic model preferences in comparison to the others. The analysis is based on quantitative survey held in the Czech Republic.

  15. Direct detection of darkmatter in radiative seesaw model

    Energy Technology Data Exchange (ETDEWEB)

    Schmidt, Daniel; Schwetz, Thomas [Max-Planck-Institut fuer Kernphysik, Heidelberg (Germany); Toma, Takashi [Institute for Theoretical Physics, Kanazawa University (Japan)


    In the radiative seesaw model proposed by Ma, we assume that the lightest right-handed neutrino is the Dark Matter candidate and almost degenerated with the second lightest right-handed neutrino. Thus, elastic Dark Matter-nucleus scattering is suppressed. Inelastic scattering is induced by a lepton-loop coupled to the photon. Effectively, there are charge-charge, dipole-charge and dipole-dipole interactions. We present the event rate of the model and compare it with existing data. Moreover, monochromatic photons from the decay of the excited Dark Matter state are discussed.

  16. Diagnosis of schizophrenia in latino populations: a comparison of direct interview and consensus based multi-source methods. (United States)

    Contreras, Javier; Dassori, Albana; Medina, Rolando; Raventos, Henriette; Ontiveros, Alfonso; Nicolini, Humberto; Munoz, Rodrigo; Escamilla, Michael


    We determined the rates of agreement between diagnoses, using the Diagnostic Interview for Genetic Studies (DIGS) and diagnoses arrived at, using additional sources of information, to establish whether there are differences in agreement between direct interview diagnoses at US and non-US sites in comparison best estimate consensus process and to identify diagnoses that could increase diagnostic error when only the DIGS is used. DIGS diagnoses were compared with consensus diagnoses that used the same DIGS interview, plus Family Interview for Genetic Studies (FIGS) and review of medical records in 342 psychotic subjects. We found similar numbers of subjects diagnosed with schizophrenia (225 by direct interview, and 232 by consensus process). The majority of those "misdiagnosed" by direct interview had mood disorder by the consensus. Over 10% of the total subjects diagnosed by direct interview as not meeting criteria for schizophrenia had schizophrenia by consensus. There were no statistically significant differences between countries (US vs. non-US sites) in the agreement rate between direct interview diagnosis and consensus diagnosis. In conclusion, a final best-estimate process is essential to make diagnostic distinctions and to reduce diagnostic misclassifications for both research studies and in clinical practice.

  17. Parallel direct solver for finite element modeling of manufacturing processes

    DEFF Research Database (Denmark)

    Nielsen, Chris Valentin; Martins, P.A.F.


    The central processing unit (CPU) time is of paramount importance in finite element modeling of manufacturing processes. Because the most significant part of the CPU time is consumed in solving the main system of equations resulting from finite element assemblies, different approaches have been d...

  18. Architecture for Direct Model-to-Part CNC Manufacturing

    Directory of Open Access Journals (Sweden)

    Gilbert Poon


    Full Text Available In the traditional paradigm for Computer Numerical Control (CNC machining, tool paths are programmed offline from the CNC machine using the Computer-Aided Design (CAD model of the workpiece. The program is downloaded to the CNC controller and the part is then machined. Since a CAD model does not exist inside the CNC controller, it is unaware of the part to be machined and cannot predict or prevent errors. Not only is this paradigm labor intensive, it can lead to catastrophic damage if there are errors during machining. This paper presents a new concept for CNC machine control whereby a CAD model of the workpiece exists inside the controller and the tool positions are generated in real-time by the controller using the computer's graphics hardware without human intervention. The new concept was implemented on an experimental lathe machine specifically designed to machine complicated ornamental wood workpieces with a personal computer. An example workpiece was machined and measured using a 3D camera. The measured data was registered to the CAD model to evaluate machining accuracy.

  19. Bi-directional approach for logical traffic isolation forensic model

    CSIR Research Space (South Africa)

    Dlamini, I


    Full Text Available -it-as-you-can" system, which seizes all packets passing through a certain traffic point, captures and writes them to the storage. The main aim of this paper is to address some of the challenges faced by the Logical Traffic Isolation (LTI) model, more specifically...

  20. Comparison of the marginal adaptation of direct and indirect composite inlay restorations with optical coherence tomography

    Directory of Open Access Journals (Sweden)

    Ayşe Gözde TÜRK

    Full Text Available ABSTRACT Objective The purpose of the study was to use the photonic imaging modality of optical coherence tomography (OCT to compare the marginal adaptation of composite inlays fabricated by direct and indirect techniques. Material and Methods Class II cavities were prepared on 34 extracted human molar teeth. The cavities were randomly divided into two groups according to the inlay fabrication technique. The first group was directly restored on cavities with a composite (Esthet X HD, Dentsply, Germany after isolating. The second group was indirectly restored with the same composite material. Marginal adaptations were scanned before cementation with an invisible infrared light beam of OCT (Thorlabs, allowing measurement in 200 µm intervals. Restorations were cemented with a self-adhesive cement resin (SmartCem2, Dentsply, and then marginal adaptations were again measured with OCT. Mean values were statistically compared by using independent-samples t-test and paired samples t-test (p<0.05, before and after cementation. Results Direct inlays presented statistically smaller marginal discrepancy values than indirect inlays, before (p=0.00001442 and after (p=0.00001466 cementation. Marginal discrepancy values were increased for all restorations after cementation (p=0.00008839, p=0.000000952 for direct and indirect inlays, respectively. The mean marginal discrepancy value of the direct group increased from 56.88±20.04 µm to 91.88±31.7 µm, whereas the indirect group increased from 107.54±35.63 µm to 170.29±54.83 µm. Different techniques are available to detect marginal adaptation of restorations, but the OCT system can give quantitative information about resin cement thickness and its interaction between tooth and restoration in a nondestructive manner. Conclusions Direct inlays presented smaller marginal discrepancy than indirect inlays. The marginal discrepancy values were increased for all restorations that refer to cement thickness after


    International Nuclear Information System (INIS)

    Frisch, Priscilla C.; Andersson, B-G; Berdyugin, Andrei; Piirola, Vilppu; Funsten, Herbert O.; Magalhaes, Antonio M.; McComas, David J.; Schwadron, Nathan A.; Slavin, Jonathan D.; Wiktorowicz, Sloane J.


    Variations in the spatial configuration of the interstellar magnetic field (ISMF) near the Sun can be constrained by comparing the ISMF direction at the heliosphere found from the Interstellar Boundary Explorer (IBEX) spacecraft observations of a 'Ribbon' of energetic neutral atoms (ENAs), with the ISMF direction derived from optical polarization data for stars within ∼40 pc. Using interstellar polarization observations toward ∼30 nearby stars within ∼90 0 of the heliosphere nose, we find that the best fits to the polarization position angles are obtained for a magnetic pole directed toward ecliptic coordinates of λ, β ∼ 263 0 , 37 0 (or galactic coordinates of l, b ∼ 38 0 , 23 0 ), with uncertainties of ±35 0 based on the broad minimum of the best fits and the range of data quality. This magnetic pole is 33 0 from the magnetic pole that is defined by the center of the arc of the ENA Ribbon. The IBEX ENA ribbon is seen in sight lines that are perpendicular to the ISMF as it drapes over the heliosphere. The similarity of the polarization and Ribbon directions for the local ISMF suggests that the local field is coherent over scale sizes of tens of parsecs. The ISMF vector direction is nearly perpendicular to the flow of local interstellar material (ISM) through the local standard of rest, supporting a possible local ISM origin related to an evolved expanding magnetized shell. The local ISMF direction is found to have a curious geometry with respect to the cosmic microwave background dipole moment.

  2. Design and Comparison of a Novel Stator Interior Permanent Magnet Generator for Direct-Drive Wind Turbines

    DEFF Research Database (Denmark)

    Zhang, Johan Xi; Chen, Zhe; Cheng, M.


    A novel stator interior permanent magnet generator (SIPMG) is presented. A modular stator design is used for convenience in manufacture and maintenance. The generator has the advantages of rugged rotor and concentrated winding design whereas the torque ripple is smaller than that produced...... by a doubly salient machine. Several low-speed multi-pole SIPMGs are designed for direct-drive wind turbines with ratings from 3 to 10 MW. Comparisons between the SIPMG and rotor-surface-mounted permanent magnet synchronous generator (PMSG) show that the SIPMGs have about 120% torque density and 78% cost per...

  3. Wind gust measurements using pulsed Doppler wind-lidar: comparison of direct and indirect techniques

    DEFF Research Database (Denmark)

    wind vector, we need information from at least three different lines of sight pointing towards different directions. The instrument sensitivity depends on the amount of aerosol present and the velocity measurement uncertainty is directly related to the amount of signal. With the commercial lidars...... traditionally used today it takes several seconds to measure each line of sight with sufficient sensitivity and therefore the temporal resolution of the wind measurement is of the order of tens of seconds, which is not sufficient for gusts. Here we deploy a fast scanning lidar (temporal resolution for a scan...

  4. A comparison of direct infusion MS and GC-MS for metabolic footprinting of yeast mutants

    DEFF Research Database (Denmark)

    Mass, S.; Villas-Bôas, Silas Granato; Hansen, Michael Adsetts Edberg


    -deletion mutants. Filtered fermentation broth samples were analyzed by GC-MS and direct infusion ESI-MS. The potential of both methods in producing specific and, therefore, discriminant metabolite profiles was evaluated using samples from several yeast deletion mutants grown in batch-culture conditions....... Thus, the GC-MS method is good for classification of mutants with altered nitrogen regulation as it primarily measures amino acids, whereas this method cannot classify mutants involved in regulation of phospholipids metabolism as well as the direct infusion MS (DI-MS) method. From the analysis, we find...

  5. CHIMERA: Top-down model for hierarchical, overlapping and directed cluster structures in directed and weighted complex networks (United States)

    Franke, R.


    In many networks discovered in biology, medicine, neuroscience and other disciplines special properties like a certain degree distribution and hierarchical cluster structure (also called communities) can be observed as general organizing principles. Detecting the cluster structure of an unknown network promises to identify functional subdivisions, hierarchy and interactions on a mesoscale. It is not trivial choosing an appropriate detection algorithm because there are multiple network, cluster and algorithmic properties to be considered. Edges can be weighted and/or directed, clusters overlap or build a hierarchy in several ways. Algorithms differ not only in runtime, memory requirements but also in allowed network and cluster properties. They are based on a specific definition of what a cluster is, too. On the one hand, a comprehensive network creation model is needed to build a large variety of benchmark networks with different reasonable structures to compare algorithms. On the other hand, if a cluster structure is already known, it is desirable to separate effects of this structure from other network properties. This can be done with null model networks that mimic an observed cluster structure to improve statistics on other network features. A third important application is the general study of properties in networks with different cluster structures, possibly evolving over time. Currently there are good benchmark and creation models available. But what is left is a precise sandbox model to build hierarchical, overlapping and directed clusters for undirected or directed, binary or weighted complex random networks on basis of a sophisticated blueprint. This gap shall be closed by the model CHIMERA (Cluster Hierarchy Interconnection Model for Evaluation, Research and Analysis) which will be introduced and described here for the first time.

  6. Comparison of Dst Forecast Models for Intense Geomagnetic Storms (United States)

    Ji, Eun-Young; Moon, Y.-J.; Gopalswamy, N.; Lee, D.-H.


    We have compared six disturbance storm time (Dst) forecast models using 63 intense geomagnetic storms (Dst Dst data and the predicted Dst during the geomagnetic storm period as well as the difference of the value of minimum Dst (Delta Dst(sub min)) and the difference in the absolute value of Dst minimum time (Delta t(sub Dst)) between the observed and the predicted. As a result, we found that the model by Temerin and Li gives the best prediction for all parameters when all 63 events are considered. The model gives the average values: the linear correlation coefficient of 0.94, the RMS error of 14.8 nT, the Delta Dst(sub min) of 7.7 nT, and the absolute value of Delta t(sub Dst) of 1.5 hour. For further comparison, we classified the storm events into two groups according to the magnitude of Dst. We found that the model of Temerin and Lee is better than the other models for the events having 100 Dst Dst <= 200 nT.

  7. Comparison of the local-scale atmospheric dispersion model Cedrat with 85KR measurements

    International Nuclear Information System (INIS)

    Rennesson, M.; Devin, P.; Maro, D.; Fitamant, M.L.; Bouland, P.


    An accurate model of atmospheric dispersion of radionuclides over the complex terrain of the La Hague reprocessing plant (North Cotentin, France) has been developed by COGEMA, in partnership with Paris VI University. This model, called CEDRAT 1.0.1 (operational since October 2002), takes into account areas typically outside the validity limits of Gaussian models: relief and building influence, short-distance (beyond 500 m from the release point) and stable atmospheric conditions. The modelling tool is based on an original method: a 2D-meshed model for flow resolution at permanent rate in the prevailing wind direction, and a 3D description of the dispersion phenomena, taking into account wet and dry deposits, at permanent or transitory rate. This leads to an effective compromise between rapidity (45 min on a 6000 nodes grid, with a standard PC), robustness and accuracy, coupled with a user-friendly interface. Primarily the validation process consisted of a comparison with the 3D complex dispersion reference model MERCURE, developed by EDF. Then, MERCURE and CEDRAT results were compared on real release scenario basis, for which actual meteorological conditions and tracer data collected at monitoring stations around the site were known. To enlarge this validation process, a second level of comparison was made in collaboration with a IRSN Cherbourg team, through different field experiments, which provided both ground and elevated level measurements (collected with a captive balloon), for different stability classes of the atmosphere. The plume tracer is krypton 85, an inert gas released from a height of 100 m. Thus, the aim of this paper is to present the original method to describe short distance dispersion over complex terrain and its validation enrichment for stability conditions and areas not yet observed, through wind and cross-wind Atmospheric Transfer Coefficients comparisons, at both ground and elevated levels. (author)

  8. Results of the eruptive column model inter-comparison study (United States)

    Costa, Antonio; Suzuki, Yujiro; Cerminara, M.; Devenish, Ben J.; Esposti Ongaro, T.; Herzog, Michael; Van Eaton, Alexa; Denby, L.C.; Bursik, Marcus; de' Michieli Vitturi, Mattia; Engwell, S.; Neri, Augusto; Barsotti, Sara; Folch, Arnau; Macedonio, Giovanni; Girault, F.; Carazzo, G.; Tait, S.; Kaminski, E.; Mastin, Larry G.; Woodhouse, Mark J.; Phillips, Jeremy C.; Hogg, Andrew J.; Degruyter, Wim; Bonadonna, Costanza


    This study compares and evaluates one-dimensional (1D) and three-dimensional (3D) numerical models of volcanic eruption columns in a set of different inter-comparison exercises. The exercises were designed as a blind test in which a set of common input parameters was given for two reference eruptions, representing a strong and a weak eruption column under different meteorological conditions. Comparing the results of the different models allows us to evaluate their capabilities and target areas for future improvement. Despite their different formulations, the 1D and 3D models provide reasonably consistent predictions of some of the key global descriptors of the volcanic plumes. Variability in plume height, estimated from the standard deviation of model predictions, is within ~ 20% for the weak plume and ~ 10% for the strong plume. Predictions of neutral buoyancy level are also in reasonably good agreement among the different models, with a standard deviation ranging from 9 to 19% (the latter for the weak plume in a windy atmosphere). Overall, these discrepancies are in the range of observational uncertainty of column height. However, there are important differences amongst models in terms of local properties along the plume axis, particularly for the strong plume. Our analysis suggests that the simplified treatment of entrainment in 1D models is adequate to resolve the general behaviour of the weak plume. However, it is inadequate to capture complex features of the strong plume, such as large vortices, partial column collapse, or gravitational fountaining that strongly enhance entrainment in the lower atmosphere. We conclude that there is a need to more accurately quantify entrainment rates, improve the representation of plume radius, and incorporate the effects of column instability in future versions of 1D volcanic plume models.

  9. A general model framework for multisymbol number comparison. (United States)

    Huber, Stefan; Nuerk, Hans-Christoph; Willmes, Klaus; Moeller, Korbinian


    Different models have been proposed for the processing of multisymbol numbers like two- and three-digit numbers but also for negative numbers and decimals. However, these multisymbol numbers are assembled from the same set of Arabic digits and comply with the place-value structure of the Arabic number system. Considering these shared properties, we suggest that the processing of multisymbol numbers can be described in one general model framework. Accordingly, we first developed a computational model framework realizing componential representations of multisymbol numbers and evaluated its validity by simulating standard empirical effects of number magnitude comparison. We observed that the model framework successfully accounted for most of these effects. Moreover, our simulations provided first evidence supporting the notion of a fully componential processing of multisymbol numbers for the specific case of comparing two negative numbers. Thus, our general model framework indicates that the processing of different kinds of multisymbol integer and decimal numbers shares common characteristics (e.g., componential representation). The relevance and applicability of our model goes beyond the case of basic number processing. In particular, we also successfully simulated effects from applied marketing and consumer research by accounting for the left-digit effect found in processing of prices. Finally, we provide evidence that our model framework can be integrated into the more general context of multiattribute decision making. In sum, this indicates that our model framework captures a general scheme of separate processing of different attributes weighted by their saliency for the task at hand. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  10. Direct model reference adaptive control of robotic arms (United States)

    Kaufman, Howard; Swift, David C.; Cummings, Steven T.; Shankey, Jeffrey R.


    The results of controlling A PUMA 560 Robotic Manipulator and the NASA shuttle Remote Manipulator System (RMS) using a Command Generator Tracker (CGT) based Model Reference Adaptive Controller (DMRAC) are presented. Initially, the DMRAC algorithm was run in simulation using a detailed dynamic model of the PUMA 560. The algorithm was tuned on the simulation and then used to control the manipulator using minimum jerk trajectories as the desired reference inputs. The ability to track a trajectory in the presence of load changes was also investigated in the simulation. Satisfactory performance was achieved in both simulation and on the actual robot. The obtained responses showed that the algorithm was robust in the presence of sudden load changes. Because these results indicate that the DMRAC algorithm can indeed be successfully applied to the control of robotic manipulators, additional testing was performed to validate the applicability of DMRAC to simulated dynamics of the shuttle RMS.

  11. A Comparison of Pyramidal Staff Training and Direct Staff Training in Community-Based Day Programs (United States)

    Haberlin, Alayna T.; Beauchamp, Ken; Agnew, Judy; O'Brien, Floyd


    This study evaluated two methods of training staff who were working with individuals with developmental disabilities: pyramidal training and consultant-led training. In the pyramidal training, supervisors were trained in the principles of applied behavior analysis (ABA) and in delivering feedback. The supervisors then trained their direct-care…

  12. Comparison of input devices in an ISEE direct timbre manipulation task

    NARCIS (Netherlands)

    Vertegaal, R.P.H.; Eaglestone, Barry


    The representation and manipulation of sound within multimedia systems is an important and currently under-researched area. The paper gives an overview of the authors' work on the direct manipulation of audio information, and describes a solution based upon the navigation of four-dimensional scaled

  13. Are Horses Like Zebras, or Vice Versa? Children's Sensitivity to the Asymmetries of Directional Comparisons (United States)

    Chestnut, Eleanor K.; Markman, Ellen M.


    Adults exhibit strong preferences when framing symmetrical relations. Adults prefer, for example, "A zebra is like a horse" to "A horse is like a zebra," and "The bicycle is near the building" to "The building is near the bicycle." This is because directional syntax requires more typical or prominent items…

  14. Data-parallel tomographic reconstruction : A comparison of filtered backprojection and direct Fourier reconstruction

    NARCIS (Netherlands)

    Roerdink, J.B.T.M.; Westenberg, M.A


    We consider the parallelization of two standard 2D reconstruction algorithms, filtered backprojection and direct Fourier reconstruction, using the data-parallel programming style. The algorithms are implemented on a Connection Machine CM-5 with 16 processors and a peak performance of 2 Gflop/s.

  15. Comparison of stability in the operative treatment of pelvic injuries in a finite element model. (United States)

    Bodzay, Tamás; Flóris, István; Váradi, Károly


    The comparison of the stability of four surgical methods for the treatment of vertically and rotationally unstable type C pelvic ring injuries. We produced a type C pelvic ring injury (type Denis II fracture of the sacrum and symphysiolysis) on a finite element model, in the case of standing on both feet. We stabilized the symphysiolysis with a five-hole reconstruction plate; the sacrum fracture was fixed in the first experiment with two, two-hole reconstruction plates on the ventral surface, in the second one we applied dorsally the transsacral, narrow DC plate, in the third one with KFI-H plate, and in the last one with iliosacral screw. Finite element modeling was performed by the use of the ALGOR software. Not only bones and joints, but joints and mechanically important ligaments were modeled as well. We measured the shift between the two surfaces of the fracture gap, compared to the results of measurements accomplished on cadaver models. Larger shift could be elicited after transsacral plating than after direct plating. These results correspond to those of the parallel investigation of the bony ligamentous cadaver pelvis specimens. The shift values after KFI-H plating and iliosacral screw fixation are larger than after direct plating, but smaller than after transsacral plating. The tension created in the implants is less than the allowed values; therefore, the choice of operation should depend on the type of injury. The finite element model may be utilized for the comparison of different methods of osteosynthesis for the treatment of injuries described above. Due to several difficulties in investigations performed on cadaver specimens, this model has undoubted utility.

  16. Direct regional energy/economic modeling (DREEM) design

    Energy Technology Data Exchange (ETDEWEB)

    Hall, P.D.; Pleatsikas, C.J.


    This report summarizes an investigation into the use of regional and multiregional economic models for estimating the indirect and induced impacts of Federally-mandated energy policies. It includes an examination of alternative types of energy policies that can impact regional economies and the available analytical frameworks for measuring the magnitudes and spatial extents of these impacts. One such analytical system, the National Regional Impact Evaluation System (NRIES), currently operational in the Bureau of Economic Analysis (BEA), is chosen for more detailed investigation. The report summarizes the models capabilities for addressing various energy policy issues and then demonstrates the applicability of the model in specified contexts by developing appropriate input data for three scenarios. These scenarios concern the multi-state impacts of alternative coal-mining-development decisions, multi-regional impacts of macroeconomic change, and the comprehensive effects of an alternative national energy supply trajectory. On the basis of this experience, the capabilities of NRIES for analyzing energy-policy issues are summarized in a concluding chapter.

  17. Supply chain management models, applications, and research directions

    CERN Document Server

    Pardalos, Panos; Romeijn, H


    This work brings together some of the most up to date research in the application of operations research and mathematical modeling te- niques to problems arising in supply chain management and e-Commerce. While research in the broad area of supply chain management enc- passes a wide range of topics and methodologies, we believe this book provides a good snapshot of current quantitative modeling approaches, issues, and trends within the field. Each chapter is a self-contained study of a timely and relevant research problem in supply chain mana- ment. The individual works place a heavy emphasis on the application of modeling techniques to real world management problems. In many instances, the actual results from applying these techniques in practice are highlighted. In addition, each chapter provides important mana- rial insights that apply to general supply chain management practice. The book is divided into three parts. The first part contains ch- ters that address the new and rapidly growing role of the inte...

  18. Model based, sensor directed remediation of underground storage tanks

    International Nuclear Information System (INIS)

    Christensen, B.; Drotning, W.; Thunborg, S.


    Sensor rich, intelligent robots which function with respect to models of their environment have significant potential to reduce the time and cost for the cleanup of hazardous waste while increasing operator safety. Sandia National Laboratories is performing experimental investigations into the application of intelligent robot control technology to the problem of removing waste stored tanks. This paper describes the experimental environment employed at Saudi with particular attention to the computing and software control environment. Intelligent system control is achieved though the integration of extensive geometric and kinematic world models with real-time sensor based control. All operator interactions with the system are validate all operator commands before execution to provide a safe operation. Sensing is used to add information to the robot system's world model and to allow sensor based sensor control during selected operations. The results of a first Critical Feature Test are reported and the potential for applying advanced intelligent control concepts to the removal of waste in storage tanks is discussed

  19. Modelling water use in global hydrological models: review, challenges and directions (United States)

    Bierkens, M. F.; de Graaf, I.; Wada, Y.; Wanders, N.; Van Beek, L. P.


    During the late 1980s and early 1990s, awareness of the shortage of global water resources lead to the first detailed global water resources assessments using regional statistics of water use and observations of meteorological and hydrological variables. Shortly thereafter, the first macroscale hydrological models (MHM) appeared. In these models, blue water (i.e., surface water and renewable groundwater) availability was calculated by accumulating runoff over a stream network and comparing it with population densities or with estimated water demand for agriculture, industry and households. In this talk we review the evolution of human impact modelling in global land models with a focus on global water resources, touching upon developments of the last 15 years: i.e. calculating human water scarcity; estimating groundwater depletion; adding dams and reservoirs; fully integrating water use (demand, withdrawal, consumption, return flow) in the hydrology; simulating the effects of land use change. We show example studies for each of these steps. We identify We identify major challenges that hamper the further development of integrated water resources modelling. Examples of these are: 1) simulating reservoir operations; 2) including local infrastructure and redistribution; 3) using the correct allocations rules; 4) projecting future water demand and water use. For each of these challenges we signify promising directions for further research.

  20. Comparison of the marginal adaptation of direct and indirect composite inlay restorations with optical coherence tomography. (United States)

    Türk, Ayşe Gözde; Sabuncu, Metin; Ünal, Sena; Önal, Banu; Ulusoy, Mübin


    The purpose of the study was to use the photonic imaging modality of optical coherence tomography (OCT) to compare the marginal adaptation of composite inlays fabricated by direct and indirect techniques. Class II cavities were prepared on 34 extracted human molar teeth. The cavities were randomly divided into two groups according to the inlay fabrication technique. The first group was directly restored on cavities with a composite (Esthet X HD, Dentsply, Germany) after isolating. The second group was indirectly restored with the same composite material. Marginal adaptations were scanned before cementation with an invisible infrared light beam of OCT (Thorlabs), allowing measurement in 200 µm intervals. Restorations were cemented with a self-adhesive cement resin (SmartCem2, Dentsply), and then marginal adaptations were again measured with OCT. Mean values were statistically compared by using independent-samples t-test and paired samples t-test (pinlays presented statistically smaller marginal discrepancy values than indirect inlays, before (p=0.00001442) and after (p=0.00001466) cementation. Marginal discrepancy values were increased for all restorations after cementation (p=0.00008839, p=0.000000952 for direct and indirect inlays, respectively). The mean marginal discrepancy value of the direct group increased from 56.88±20.04 µm to 91.88±31.7 µm, whereas the indirect group increased from 107.54±35.63 µm to 170.29±54.83 µm. Different techniques are available to detect marginal adaptation of restorations, but the OCT system can give quantitative information about resin cement thickness and its interaction between tooth and restoration in a nondestructive manner. Direct inlays presented smaller marginal discrepancy than indirect inlays. The marginal discrepancy values were increased for all restorations that refer to cement thickness after cementation.

  1. Estimating Steatosis Prevalence in Overweight and Obese Children: Comparison of Bayesian Small Area and Direct Methods

    Directory of Open Access Journals (Sweden)

    Hamid Reza Khalkhali


    Full Text Available Background Often, there is no access to sufficient sample size to estimate the prevalence using the method of direct estimator in all areas. The aim of this study was to compare small area’s Bayesian method and direct method in estimating the prevalence of steatosis in obese and overweight children. Materials and Methods: In this cross-sectional study, was conducted on 150 overweight and obese children aged 2 to 15 years referred to the Children's digestive clinic of Urmia University of Medical Sciences- Iran, in 2013. After Body mass index (BMI calculation, children with overweight and obese were assessed in terms of primary tests of obesity screening. Then children with steatosis confirmed by abdominal Ultrasonography, were referred to the laboratory for doing further tests. Steatosis prevalence was estimated by direct and Bayesian method and their efficiency were evaluated using mean-square error Jackknife method. The study data was analyzed using the open BUGS3.1.2 and R2.15.2 software. Results: The findings indicated that estimation of steatosis prevalence in children using Bayesian and direct methods were between 0.3098 to 0.493, and 0.355 to 0.560 respectively, in Health Districts; 0.3098 to 0.502, and 0.355 to 0.550 in Education Districts; 0.321 to 0.582, and 0.357 to 0.615 in age groups; 0.313 to 0.429, and 0.383 to 0.536 in sex groups. In general, according to the results, mean-square error of Bayesian estimation was smaller than direct estimation (P

  2. Comparison of esophageal placement of Bravo capsule system under direct endoscopic guidance with conventional placement method

    Directory of Open Access Journals (Sweden)

    Aijaz A Sofi


    Full Text Available Aijaz A Sofi, Charles Filipiak, Thomas Sodeman, Usman Ahmad, Ali Nawras, Isam DaboulDepartment of Medicine, Division of Gastroenterology, University of Toledo Medical Center, Toledo, Ohio, USABackground: Conventional placement of a wireless esophageal pH monitoring device in the esophagus requires initial endoscopy to determine the distance to the gastroesophageal junction. Blind placement of the capsule by the Bravo delivery system is followed by repeat endoscopy to confirm placement. Alternatively, the capsule can be placed under direct vision during endoscopy. Currently there are no published data comparing the efficiency of one method over the other. The objective of this study was to compare the method of Bravo wireless pH deviceplacement under direct visualization with the conventional method.Methods: A retrospective study involving 58 patients (29 patients with indirect and 29 patients with direct visualization who had Bravo capsule placement. The physician endoscopy procedure notes, nurse’s notes, postprocedure notes, recovery notes, and pH monitoring results were reviewed. The safety of the procedures, length of the procedures, and patient tolerability were evaluated.Results: None of the 58 patients had early detachment of the device and had no immediate procedure-related complications. The overall incidence of complications in both the groups was similar. No failures due to the technique were noted in either group. Average amount of time taken for the procedure was similar in both groups.Conclusion: The technique of placing a Bravo pH device under direct visualization is as safe and effective as the conventional method. In addition, there is an added advantage of avoiding a second endoscopic intubation in the direct visualization technique.Keywords: Bravo capsule, technique, esophageal pH monitoring

  3. 75 FR 81417 - Airworthiness Directives; Piper Aircraft, Inc. Model PA-28-161 Airplanes (United States)


    ... Airworthiness Directives; Piper Aircraft, Inc. Model PA-28-161 Airplanes AGENCY: Federal Aviation Administration... effective February 1, 2011. Affected ADs (b) None. Applicability (c) This AD applies to Model PA-28-161...

  4. Transcranial Direct Current Stimulation and behavioral models of smoking addiction

    Directory of Open Access Journals (Sweden)

    Paige eFraser


    Full Text Available While few studies have applied transcranial direct current stimulation (tDCS to smoking addiction, existing work suggests that the intervention holds promise for altering the complex system by which environmental cues interact with cravings to drive behavior. Imaging and repetitive transcranial magnetic stimulation (rTMS studies suggest that increased dorsolateral prefrontal cortex (DLPFC activation and integrity may be associated with increased resistance to smoking cues. Anodal tDCS of the DLPFC, believed to boost activation, reduces cravings in response to these cues. The finding that noninvasive stimulation modifies cue induced cravings has profound implications for understanding the processes underlying addiction and relapse. TDCS can also be applied to probe mechanisms underlying and supporting nicotine addiction, as was done in a pharmacologic study that applied nicotine, tDCS, and TMS paired associative stimulation to find that stopping nicotine after chronic use induces a reduction in plasticity, causing difficulty in breaking free from association between cues and cravings. This mini-review will place studies that apply tDCS to smokers in the context of research involving the neural substrates of nicotine addiction.

  5. Assessing dengue vaccination impact: Model challenges and future directions. (United States)

    Recker, Mario; Vannice, Kirsten; Hombach, Joachim; Jit, Mark; Simmons, Cameron P


    In response to the sharp rise in the global burden caused by dengue virus (DENV) over the last few decades, the WHO has set out three specific key objectives in its disease control strategy: (i) to estimate the true burden of dengue by 2015; (ii) a reduction in dengue mortality by at least 50% by 2020 (used as a baseline); and (iii) a reduction in dengue morbidity by at least 25% by 2020. Although various elements will all play crucial parts in achieving this goal, from diagnosis and case management to integrated surveillance and outbreak response, sustainable vector control, vaccine implementation and finally operational and implementation research, it seems clear that new tools (e.g. a safe and effective vaccine and/or effective vector control) are key to success. The first dengue vaccine was licensed in December 2015, Dengvaxia® (CYD-TDV) developed by Sanofi Pasteur. The WHO has provided guidance on the use of CYD-TDV in endemic countries, for which there are a variety of considerations beyond the risk-benefit evaluation done by regulatory authorities, including public health impact and cost-effectiveness. Population-level vaccine impact and economic and financial aspects are two issues that can potentially be considered by means of mathematical modelling, especially for new products for which empirical data are still lacking. In December 2014 a meeting was convened by the WHO in order to revisit the current status of dengue transmission models and their utility for public health decision-making. Here, we report on the main points of discussion and the conclusions of this meeting, as well as next steps for maximising the use of mathematical models for vaccine decision-making. Copyright © 2016.

  6. Lateral-Directional Parameter Estimation on the X-48B Aircraft Using an Abstracted, Multi-Objective Effector Model (United States)

    Ratnayake, Nalin A.; Waggoner, Erin R.; Taylor, Brian R.


    The problem of parameter estimation on hybrid-wing-body aircraft is complicated by the fact that many design candidates for such aircraft involve a large number of aerodynamic control effectors that act in coplanar motion. This adds to the complexity already present in the parameter estimation problem for any aircraft with a closed-loop control system. Decorrelation of flight and simulation data must be performed in order to ascertain individual surface derivatives with any sort of mathematical confidence. Non-standard control surface configurations, such as clamshell surfaces and drag-rudder modes, further complicate the modeling task. In this paper, time-decorrelation techniques are applied to a model structure selected through stepwise regression for simulated and flight-generated lateral-directional parameter estimation data. A virtual effector model that uses mathematical abstractions to describe the multi-axis effects of clamshell surfaces is developed and applied. Comparisons are made between time history reconstructions and observed data in order to assess the accuracy of the regression model. The Cram r-Rao lower bounds of the estimated parameters are used to assess the uncertainty of the regression model relative to alternative models. Stepwise regression was found to be a useful technique for lateral-directional model design for hybrid-wing-body aircraft, as suggested by available flight data. Based on the results of this study, linear regression parameter estimation methods using abstracted effectors are expected to perform well for hybrid-wing-body aircraft properly equipped for the task.

  7. Direct comparisons of commercial weight-loss programs on weight, waist circumference, and blood pressure: a systematic review

    Directory of Open Access Journals (Sweden)

    Rachit M. Vakil


    Full Text Available Abstract Background Obesity is common in the U.S. and many individuals turn to commercial programs to lose weight. Our objective was to directly compare weight loss, waist circumference, and systolic and diastolic blood pressure (SBP, DBP outcomes between commercially available weight-loss programs. Methods We conducted a systematic review by searching MEDLINE and the Cochrane Database of Systematic Reviews from inception to November 2014 and by using references identified by commercial programs. We included randomized, controlled trials (RCTs of at least 12 weeks duration that reported comparisons with other commercial weight-loss programs. Two reviewers extracted information on mean change in weight, waist circumference, SBP and DBP and assessed risk of bias. Results We included seven articles representing three RCTs. Curves participants lost 1.8 kg (95%CI: 0.1, 3.5 kg more than Weight Watchers in one comparison. There was no statistically significant difference in waist circumference change among the included programs. The mean reduction in SBP for SlimFast participants was 4.5 mmHg (95%CI: 0.4, 8.6 mmHg more than that of Atkins participants in one comparison. There was no significant difference in mean DBP changes among programs. Conclusions There is limited evidence that any one of the commercial weight-loss programs has superior results for mean weight change, mean waist circumference change, or mean blood pressure change.

  8. Model of the direct solar-pumped iodine photodissociation laser (United States)

    Alexandrov, Boris S.; Fokanov, V. P.; Kudryavtsev, S. N.; Pavlov, A. B.


    The results of the experimental and theoretical DSPIL modeling are presented. The parameters of the generation pulse (energy, duration, delay time) are measured for the series of perfluoriodide laser compounds under pumping conditions imitating the space solar radiation spectrum. The time dependence of the radiation spectrum was measured for the pumping pulse. The spectrum of this pulse corresponds to the ABB spectrum with temperature 6000 K in the pulse beginning and 3500 K in the end. The generation energy ratio (E10/E1) in repeatedly pumping pulse action without the active laser medium change was measured in this experiment. The empirical linear dependence between quantities 1n(E10/E1) and 1n(k3/k4) is received, where E1 and E10 are the energies of generation pulse after first and tenth pumping pulses. The mathematical model of DSPIL, containing the main kinetical processes description, is developed. The computing evaluation of the energy characteristics of DSPIL are presented.

  9. Modeling of Direct Contact Wet Cooling Tower in ETRR-2

    International Nuclear Information System (INIS)

    El Khatib, H.H.; Ismail, A.L.; ElRefaie, M.E.


    The Egyptian Testing and Research Reactor no.2 (ETRR-2) was commissioned at 1997 with maximum power 22 MW for research purposes; an induced draft wet cooling tower (counter flow type) was putted in operation in 2003 instead of the first one. Investigations are achieved to evaluate cooling tower performance to guarantee that the cooling tower capable to dissipate heat generated in reactor core. Merkel and Poppe analysis was applied to simulate this cooling tower packing. Merkel analysis was applied to predict water outlet temperature from cooling tower and also to show the effect of ambient conditions on this temperature. Poppe analysis was applied to predict Merkel number which evaluate cooling tower. The Runge-Kutta numerical method was applied to solve the differential equations in this model and an engineering equation solver (EES) is the language used to model the cooling tower. This research illustrates that the cooling tower achieves good performance in various sever ambient condition at maximum operating condition of reactor power. The results show that at severe summer condition of wet bulb temperature equals 24 degree c and tower inlet temperature equals 37 degree c, the outlet water temperature equals 30.4 degree c from cooling tower, while the Merkel number is be found 1.253

  10. Impact Flash Physics: Modeling and Comparisons With Experimental Results (United States)

    Rainey, E.; Stickle, A. M.; Ernst, C. M.; Schultz, P. H.; Mehta, N. L.; Brown, R. C.; Swaminathan, P. K.; Michaelis, C. H.; Erlandson, R. E.


    Hypervelocity impacts frequently generate an observable "flash" of light with two components: a short-duration spike due to emissions from vaporized material, and a long-duration peak due to thermal emissions from expanding hot debris. The intensity and duration of these peaks depend on the impact velocity, angle, and the target and projectile mass and composition. Thus remote sensing measurements of planetary impact flashes have the potential to constrain the properties of impacting meteors and improve our understanding of impact flux and cratering processes. Interpreting impact flash measurements requires a thorough understanding of how flash characteristics correlate with impact conditions. Because planetary-scale impacts cannot be replicated in the laboratory, numerical simulations are needed to provide this insight for the solar system. Computational hydrocodes can produce detailed simulations of the impact process, but they lack the radiation physics required to model the optical flash. The Johns Hopkins University Applied Physics Laboratory (APL) developed a model to calculate the optical signature from the hot debris cloud produced by an impact. While the phenomenology of the optical signature is understood, the details required to accurately model it are complicated by uncertainties in material and optical properties and the simplifications required to numerically model radiation from large-scale impacts. Comparisons with laboratory impact experiments allow us to validate our approach and to draw insight regarding processes that occur at all scales in impact events, such as melt generation. We used Sandia National Lab's CTH shock physics hydrocode along with the optical signature model developed at APL to compare with a series of laboratory experiments conducted at the NASA Ames Vertical Gun Range. The experiments used Pyrex projectiles to impact pumice powder targets with velocities ranging from 1 to 6 km/s at angles of 30 and 90 degrees with respect to

  11. Accuracy and reliability of 3D stereophotogrammetry: A comparison to direct anthropometry and 2D photogrammetry. (United States)

    Dindaroğlu, Furkan; Kutlu, Pınar; Duran, Gökhan Serhat; Görgülü, Serkan; Aslan, Erhan


    To evaluate the accuracy of three-dimensional (3D) stereophotogrammetry by comparing it with the direct anthropometry and digital photogrammetry methods. The reliability of 3D stereophotogrammetry was also examined. Six profile and four frontal parameters were directly measured on the faces of 80 participants. The same measurements were repeated using two-dimensional (2D) photogrammetry and 3D stereophotogrammetry (3dMDflex System, 3dMD, Atlanta, Ga) to obtain images of the subjects. Another observer made the same measurements for images obtained with 3D stereophotogrammetry, and interobserver reproducibility was evaluated for 3D images. Both observers remeasured the 3D images 1 month later, and intraobserver reproducibility was evaluated. Statistical analysis was conducted using the paired samples t-test, intraclass correlation coefficient, and Bland-Altman limits of agreement. The highest mean difference was 0.30 mm between direct measurement and photogrammetry, 0.21 mm between direct measurement and 3D stereophotogrammetry, and 0.5 mm between photogrammetry and 3D stereophotogrammetry. The lowest agreement value was 0.965 in the Sn-Pro parameter between the photogrammetry and 3D stereophotogrammetry methods. Agreement between the two observers varied from 0.90 (Ch-Ch) to 0.99 (Sn-Me) in linear measurements. For intraobserver agreement, the highest difference between means was 0.33 for observer 1 and 1.42 mm for observer 2. Measurements obtained using 3D stereophotogrammetry indicate that it may be an accurate and reliable imaging method for use in orthodontics.

  12. The Determinants of Foreign Direct Investment in Europe and Asia: A Comparison Study


    Deogratias, Denis Dawson


    ABSTRACT This research study makes use of the institutional FDI fitness framework to study and compare the main determinants of foreign direct investment in Europe and Asia. The main categories of FDI fitness explored included market fitness, government fitness and educational fitness. Within these, variables such as GDP, annual GDP growth, inflation, domestic credit, school enrolment, political stability and corruption perception were evaluated. Using panel data techniques to test th...

  13. Feedback in formative OSCEs: comparison between direct observation and video-based formats

    Directory of Open Access Journals (Sweden)

    Noëlle Junod Perron


    Full Text Available Introduction: Medical students at the Faculty of Medicine, University of Geneva, Switzerland, have the opportunity to practice clinical skills with simulated patients during formative sessions in preparation for clerkships. These sessions are given in two formats: 1 direct observation of an encounter followed by verbal feedback (direct feedback and 2 subsequent review of the videotaped encounter by both student and supervisor (video-based feedback. The aim of the study was to evaluate whether content and process of feedback differed between both formats. Methods: In 2013, all second- and third-year medical students and clinical supervisors involved in formative sessions were asked to take part in the study. A sample of audiotaped feedback sessions involving supervisors who gave feedback in both formats were analyzed (content and process of the feedback using a 21-item feedback scale. Results: Forty-eight audiotaped feedback sessions involving 12 supervisors were analyzed (2 direct and 2 video-based sessions per supervisor. When adjusted for the length of feedback, there were significant differences in terms of content and process between both formats; the number of communication skills and clinical reasoning items addressed were higher in the video-based format (11.29 vs. 7.71, p=0.002 and 3.71 vs. 2.04, p=0.010, respectively. Supervisors engaged students more actively during the video-based sessions than during direct feedback sessions (self-assessment: 4.00 vs. 3.17, p=0.007; active problem-solving: 3.92 vs. 3.42, p=0.009. Students made similar observations and tended to consider that the video feedback was more useful for improving some clinical skills. Conclusion: Video-based feedback facilitates discussion of clinical reasoning, communication, and professionalism issues while at the same time actively engaging students. Different time and conceptual frameworks may explain observed differences. The choice of feedback format should depend on

  14. Comparison Of Direct Simple Shear Confinement Methods On Clay And Silt Specimens (United States)


    SUBJECT TERMS 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT 18. NUMBER OF PAGES 19a. NAME OF RESPONSIBLE PERSON a. REPORT...methods performed in the Marine Geomechanics Laboratory at the University of Rhode Island. In this chapter sample preparation, storage, equipment, and... Geomechanics Laboratory at the University of Rhode Island. Direct simple shear tests allow for the measurement of maximum horizontal shear stress of

  15. Direct coal liquefaction: general characteristics and comparison with other methods of manufacturing synthetic fuels

    Energy Technology Data Exchange (ETDEWEB)

    Legarreta, J.A.; Arias, P.L.; Cambra, J.F.; Gutierrez-Canas, C.


    Direct liquefaction has considerable advantages over other methods available for coal beneficiation by the manufacture of liquid fuels, namely: it requires a lower chemical reaction and is therefore a more efficient method which consumes less energy; it requires less stringent operating conditions which reduces equipment costs; synthetic liquid fuel is a much more concentrated form of energy than gas which makes it easier to store and transport; and liquefaction plants require less water and produce less liquid and gaseous effluents. 10 references.

  16. Comparison of latex agglutination and immunofluorescence for direct Lancefield grouping of streptococci from blood cultures.


    Shlaes, D M; Toossi, Z; Patel, A


    Simulated positive blood cultures with 84 known stock strains of streptococci were used to comparatively evaluate the direct identification of these organisms by fluorescein-tagged antibody staining (immunofluorescence [IF]) and latex agglutination (LA). IF was not evaluated for Lancefield group D strains (a total of 81 strains tested) and had 89% sensitivity and 91% specificity. IF was least sensitive for the identification of Lancefield group F, in which three of seven strains showed no flu...

  17. Comparison of direct and indirect measures of predation in different populations of primates


    Petrena, Vanja


    Predation is thought to play a major role in the evolution of morfology, fisiology and behavior of primates. However, it is hard to observe and measure, which lead some resarchers to use indirect measures of predation when trying to evaluate predation presaure. In my diploma thesis I investigated the relationship between a direct measure of predation – estimated predation rates (EPR) – and two proxy measures, body mass and terrestriality (terrestrial/arboreal way of living). From the existin...

  18. Comparison of stabilities in translucency, fluorescence and opalescence of direct and indirect composite resins. (United States)

    Yu, Bin; Lee, Young-Keun


    To evaluate translucency, fluorescence and opalescence stabilities of direct and indirect composite resins after aging. One direct (16 shades) and two indirect composite resins (16 and 26 shades) were investigated. Resins were filled in a mold (1 mm thick) and light cured; post-curings were performed for indirect resins. Color was measured before and after 5,000 cycles of thermocycling on a reflection spectrophotometer in reflectance and transmittance modes to calculate parameters for translucency (TP), fluorescence (FL) and opalescence (OP). Differences in the changes of TP, FL and OP after aging by the type of resin were determined by t test, and those were also determined by one-way ANOVA with the factor of the brand or the shade group (P resins; and were -2.0 to 1.8, -0.9 to 0.4 and -2.9 to 3.7, respectively, for indirect resins. Changes in TP were not significantly different by the type of resin, but those in FL and OP were different (P = 0.05). Changes in optical parameters were influenced by the brand or the shade group of the resins (P resins varied depending on type, brand or shade group. Aging significantly affected fluorescence and opalescence, but not translucency, of indirect resins compared to those of direct resins.

  19. Assessment of directionality performances: comparison between Freedom and CP810 sound processors. (United States)

    Razza, Sergio; Albanese, Greta; Ermoli, Lucilla; Zaccone, Monica; Cristofari, Eliana


    To compare speech recognition in noise for the Nucleus Freedom and CP810 sound processors using different directional settings among those available in the SmartSound portfolio. Single-subject, repeated measures study. Tertiary care referral center. Thirty-one monoaurally and binaurally implanted subjects (24 children and 7 adults) were enrolled. They were all experienced Nucleus Freedom sound processor users and achieved a 100% open set word recognition score in quiet listening conditions. Each patient was fitted with the Freedom and the CP810 processor. The program setting incorporated Adaptive Dynamic Range Optimization (ADRO) and adopted the directional algorithm BEAM (both devices) and ZOOM (only on CP810). Speech reception threshold (SRT) was assessed in a free-field layout, with disyllabic word list and interfering multilevel babble noise in the 3 different pre-processing configurations. On average, CP810 improved significantly patients' SRTs as compared to Freedom SP after 1 hour of use. Instead, no significant difference was observed in patients' SRT between the BEAM and the ZOOM algorithm fitted in the CP810 processor. The results suggest that hardware developments achieved in the design of CP810 allow an immediate and relevant directional advantage as compared to the previous-generation Freedom device.

  20. Comparison of Sniffing Position and Simple Head Extension for Visualization of Glottis During Direct Laryngoscopy

    Directory of Open Access Journals (Sweden)

    Suresh Kumar Singhal


    Full Text Available The prospective randomized study comprised of 200 patients in the age group of 20 to 60 years, belonging to ASA physical status grade I or II, undergoing elective surgery under general anaesthesia with tracheal intubation. The aim was to compare sniffing position with simple head extension for visualization of glottis during direct laryngos-copy and ease of tracheal intubation. All the patients were randomly divided in two groups of 100 each: Group A (sniffing position and Group B (simple head extension. Direct laryngoscopy was done using Macintosh laryngo-scope (size 3 blade. Glottic visualization during laryngoscopy was assessed using modified Cormack and Lehane classification. After laryngoscopy, tracheal intubation was performed and intubation difficulty score (IDS recorded. Both groups were comparable regarding glottic visualization (P>0.05. All intubation difficulty score variables (N 1 to N 7 were comparable in the two groups except N 3 variable, which was significantly higher (P< 0.05 in simple head extension position. Total IDS was significantly better in sniffing position than simple head extension position (P< 0.05. To conclude, glottis visualization and intubation difficulty score are better in sniffing position as compared to simple head extension. It is too early to abandon this gold standard (sniffing position for direct laryngoscopy and tracheal intubation.

  1. A comparison of metal accumulation by the cnidarian Hydra vulgaris directly from water or

    Directory of Open Access Journals (Sweden)

    Wanchamai Karntanut


    Full Text Available The cnidarian Hydra has been widely used to assess the acute toxicity of freshwater pollutants, but very little is known about pollutant accumulation by this animal. The purpose of this study was to measurethe accumulation of the three metals, i.e., copper, cadmium and zinc directly from water and also via its prey and to relate the recorded tissue concentrations to any change in biological activities. It was found thatcopper, cadmium and zinc all were accumulated in the tissues of Hydra exposed directly to the metals in water and also those exposed indirectly through feeding on contaminated prey. The bioconcentration factor(BCF recorded at 48 hours following direct uptake from water was greatest for copper (773, followed by cadmium (409 and zinc (125, although the greatest increase in body burden occurred with cadmium, Metal body burdens of Hydra fed on contaminated prey (Artemia increased in the same metal sequence as fordirect uptake from water and the increase was highest (250 times that of control Hydra for cadmium; however, biomagnification factors (BMFs were all < 1.0 indicating that there was little potential for increasingaccumulation via the food chain. There was significant inhibition of regeneration and bud production in polyps which had fed on cadmium-containing Artemia but not on copper or zinc- containing Artemia.

  2. Modeling of Pulsed Direct-Current Glow Discharge

    International Nuclear Information System (INIS)

    Du Mu; Zheng Yaru; Fan Yujia; Zhang Nan; Liu Chengsen; Wang Dezhen


    A self-consistent model was adopted to study the time evolution of low-voltage pulsed DC glow discharge. The distributions of electric field, ion density and electron density in nitrogen were investigated in our simulation, and the temporal shape of the discharge current was also obtained. Our results show that the dynamic behaviors of the discharge depends strongly on the applied pulse voltage, and the use of higher pulse voltages results in a significantly increase of discharge current and a decrease of discharge delay time. The current-voltage characteristic calculated by adjusting secondary electron emission coefficient for different applied pulse voltage under the gas pressure of 1 Torr is found in a reasonable agreement with the experimental results.

  3. Discovery of non-directional and directional pioneer transcription factors by modeling DNase profile magnitude and shape (United States)

    Lewis, Sophia; Barkal, Amira A; van Hoff, John Peter; Karun, Vivek; Jaakkola, Tommi; Gifford, David K


    Here we describe Protein Interaction Quantitation (PIQ), a computational method that models the magnitude and shape of genome-wide DNase profiles to facilitate the identification of transcription factor (TF) binding sites. Through the use of machine learning techniques, PIQ identified binding sites for >700 TFs from one DNase-seq experiment with accuracy comparable to ChIP-seq for motif-associated TFs (median AUC=0.93 across 303 TFs). We applied PIQ to analyze DNase-seq data from mouse embryonic stem cells differentiating into pre-pancreatic and intestinal endoderm. We identified (n=120) and experimentally validated eight ‘pioneer’ TF families that dynamically open chromatin, enabling other TFs to bind to adjacent DNA. Four pioneer TF families only open chromatin in one direction from their motifs. Furthermore, we identified a class of ‘settler’ TFs whose genomic binding is principally governed by proximity to open chromatin. Our results support a model of hierarchical TF binding in which directional and non-directional pioneer activity shapes the chromatin landscape for population by settler TFs. PMID:24441470

  4. Comparison of Fuzzy-Based Models in Landslide Hazard Mapping (United States)

    Mijani, N.; Neysani Samani, N.


    Landslide is one of the main geomorphic processes which effects on the development of prospect in mountainous areas and causes disastrous accidents. Landslide is an event which has different uncertain criteria such as altitude, slope, aspect, land use, vegetation density, precipitation, distance from the river and distance from the road network. This research aims to compare and evaluate different fuzzy-based models including Fuzzy Analytic Hierarchy Process (Fuzzy-AHP), Fuzzy Gamma and Fuzzy-OR. The main contribution of this paper reveals to the comprehensive criteria causing landslide hazard considering their uncertainties and comparison of different fuzzy-based models. The quantify of evaluation process are calculated by Density Ratio (DR) and Quality Sum (QS). The proposed methodology implemented in Sari, one of the city of Iran which has faced multiple landslide accidents in recent years due to the particular environmental conditions. The achieved results of accuracy assessment based on the quantifier strated that Fuzzy-AHP model has higher accuracy compared to other two models in landslide hazard zonation. Accuracy of zoning obtained from Fuzzy-AHP model is respectively 0.92 and 0.45 based on method Precision (P) and QS indicators. Based on obtained landslide hazard maps, Fuzzy-AHP, Fuzzy Gamma and Fuzzy-OR respectively cover 13, 26 and 35 percent of the study area with a very high risk level. Based on these findings, fuzzy-AHP model has been selected as the most appropriate method of zoning landslide in the city of Sari and the Fuzzy-gamma method with a minor difference is in the second order.

  5. Comparison between two models of elbow rehabilitation equipment

    Directory of Open Access Journals (Sweden)

    Vetrice Georgiana


    Full Text Available International studies have revealed that using continuous passive motion (CPM equipment as part of a rehabilitation program improves the recovery period and also diminishes the rehabilitation costs by about 50%. This explains the need for conceiving elbow joint rehabilitation equipment to help persons suffering from posttraumatic disabilities. In order to create the best model to meet the patients’ requirements this paper presents two constructive solutions of such equipment and a comparison between their designs. Both achieve the desired movements of the elbow joint: flexion-extension and pronation-supination and are actuated by pneumatic muscles, due to the multiple advantages of pneumatic actuation: low cost, compliance and favorable response to commands.

  6. Microphysical modelling of volcanic plumes / Comparisons against groundbased and spaceborne lidar data (United States)

    Jumelet, Julien; Bekki, Slimane; Keckhut, Philippe


    We present a high-resolution isentropic microphysical transport model dedicated to stratospheric aerosols and clouds. The model is based on the MIMOSA model (Modélisation Isentrope du transport Méso-échelle de l'Ozone Stratosphérique par Advection) and adds several modules: a fully explicit size-resolving microphysical scheme to transport aerosol granulometry as passive tracers and an optical module, able to calculate the scattering and extinction properties of particles at given wavelengths. Originally designed for polar stratospheric clouds (composed of sulfuric acid, nitric acid and water vapor), the model is fully capable of rendering the structure and properties of volcanic plumes at the finer scales, assuming complete SO2 oxydation. This link between microphysics and optics also enables the model to take advantage of spaceborne lidar data (i.e. CALIOP) by calculating the 532nm aerosol backscatter coefficient, taking it as the control variable to provide microphysical constraints during the transport. This methodology has been applied to simulate volcanic plumes during relatively recent volcanic eruptions, from the 2010 Merapi to the 2015 Calbuco eruption. Optical calculations are also used for direct comparisons between the model and groundbased lidar stations for validation as well as characterization purposes. We will present the model and the simulation results, along with a focus on the sensitivity to initialisation parameters, considering the need for quasi-real time modelling and forecasts in the case of future eruptions.

  7. EMF 7 model comparisons: key relationships and parameters

    Energy Technology Data Exchange (ETDEWEB)

    Hickman, B.G.


    A simplified textbook model of aggregate demand and supply interprets the similarities and differences in the price and income responses of the various EMF 7 models to oil and policy shocks. The simplified model is a marriage of Hicks' classic IS-LM formulation of the Keynesian theory of effective demand with a rudimentary model of aggregate supply, combining a structural Phillips curve for wage determination and a markup theory of price determination. The reduced-form income equation from the fix-price IS-LM model is used to define an aggregate demand (AD) locus in P-Y space, showing alternative pairs of the implicit GNP deflator and real GNP which would simultaneously satisfy the saving-investment identity and the condition for money market equilibrium. An aggregate supply (AS) schedule is derived by a similar reduction of relations between output and labor demand, unemployment and wage inflation, and the wage-price-productivity nexus governing markup pricing. Given a particular econometric model it is possible to derive IS and LM curves algebraically. The resulting locuses would show alternative combinations of interest rate and real income which equilibrate real income identity on the IS side and the demand and supply of money on the LM side. By further substitution the reduced form fix-price income relation could be obtained for direct quantification of the AD locus. The AS schedule is obtainable by algebraic reduction of the structural supply side equations.

  8. Testing evolutionary models of senescence: traditional approaches and future directions. (United States)

    Robins, Chloe; Conneely, Karen N


    From an evolutionary perspective, the existence of senescence is a paradox. Why has senescence not been more effectively selected against given its associated decreases in Darwinian fitness? Why does senescence exist and how has it evolved? Three major theories offer explanations: (1) the theory of mutation accumulation suggested by PB Medawar; (2) the theory of antagonistic pleiotropy suggested by GC Williams; and (3) the disposable soma theory suggested by TBL Kirkwood. These three theories differ in the underlying causes of aging that they propose but are not mutually exclusive. This paper compares the specific biological predictions of each theory and discusses the methods and results of previous empirical tests. Lifespan is found to be the most frequently used estimate of senescence in evolutionary investigations. This measurement acts as a proxy for an individual's rate of senescence, but provides no information on an individual's senescent state or "biological age" throughout life. In the future, use of alternative longitudinal measures of senescence may facilitate investigation of previously neglected aspects of evolutionary models, such as intra- and inter-individual heterogeneity in the process of aging. DNA methylation data are newly proposed to measure biological aging and are suggested to be particularly useful for such investigations.

  9. Performance Characteristics Comparison of CNG Port and CNG Direct Injection in Spark Ignition Engine

    Directory of Open Access Journals (Sweden)

    Rajesh Patel


    Full Text Available A comparative performance analysis is being carried out on a four cylinder, four stroke cycle, spark ignition engine having displacement volume 1297cc. The cylinder head of original gasoline based engine was modified by drilling holes from upper surfaces of head to individual combustion chamber to convert the engine in a CNG direct injection engine. The CNG port injection (CNG-PI system and CNG direct injection (CNG-DI system were incorporated with the single engine.  The engine was retrofitted to run on both CNG-PI and CNG-DI system alternately with common CNG tank and other engine loading and measurement system. The engine was equipped with electrical dynamometer having rheostat type loading. The CNG direct injection system was incorporated with various sensors and engine ECU. The operating parameters can be obtained on computer screen by loading the computer with engine through switch box. The engine was run over the speed range of 1000 rpm to 3000 rpm with incremental speed of 300 rpm. The performance parameters were calculated from observations and recorded for both CNG-PI and CNG-DI system. The experimental investigation exhibits that, the average 7-8% reduction in BSFC while the engine was running with CNG-DI system as compared to that of CNG-PI system. Also the engine produced 8-9% higher brake torque and hence higher brake power. The engine gives 6-7% higher brake thermal efficiency with CNG-DI system as compared to CNG-PI system.

  10. Comparison of video, optical, and direct laryngoscopy by experienced tactical paramedics. (United States)

    Yun, Brian J; Brown, Calvin A; Grazioso, Christopher J; Pozner, Charles N; Raja, Ali S


    While optical and video laryngoscopy have been studied in the emergency department, the operating room, and the routine prehospital setting, their efficacy in the tactical environment--in which operator safety is as important as intubation success--has not been evaluated. This study compared direct laryngoscopes to optical (AirTraq) and video (King Vision) laryngoscopes in a simulated tactical setting. This prospective institutional review board-approved simulation study evaluated each of the laryngoscopes in the hands of seven experienced tactical paramedics. After a one-hour training session, each tactical paramedic used each of the laryngoscopes, in a random order, on each of four different airway manikins. A tactical environment was simulated using auditory and visual immersion, and the intubations occurred on the ground with the paramedics in full tactical gear. Outcomes included time to successful ventilation, first-pass success rate, Cormack-Lehane grade, and intubator head height during the intubation. Statistical analysis included chi-squared and Wilcoxon rank sum tests, and multivariate logistic regression was performed to determine contributing factors to outcomes with significant variation. A total of 84 intubations were performed by seven tactical paramedics. While there were no significant differences in time to successful ventilation or first-pass success rate, the optical and video laryngoscopes had significantly better Cormack-Lehane grades, defined as grade I or II (100% for both compared to 85.7%), while direct laryngoscopy resulted in significantly less maximum vertical exposure of the intubator (51.82 cm compared to AirTraq's 56.64 cm and King Vision's 56.13 cm). Video and optical laryngoscopes can be used successfully by experienced tactical paramedics in a simulated tactical setting. The King Vision and AirTraq resulted in improved Cormack-Lehane glottic views but similar times to ventilation and first-pass success compared to direct

  11. A comparison between two optimized TFPM geometries for 5 MW direct-drive wind turbines

    DEFF Research Database (Denmark)

    Nica, Florin Valentin Traian; Ritchie, Ewen; Leban, Krisztina Monika


    for the industry. The approach presented in this paper focuses on a reduction in mass of active materials, which constitute the generator, because the price of the machine is in direct relation with the amount of materials used for the construction. This strategy is applied for two types of TFPM geometries...... in order to asses which behaves better when subjected to optimization and which provides the best result. In order to obtain the mass of active materials the entire analytical design has to be covered, making the analytical design to behave as a cost function for the optimization program. The innovation...

  12. Evolution and Morphogenesis of Simulated Modular Robots: A Comparison Between a Direct and Generative Encoding

    DEFF Research Database (Denmark)

    Veenstra, Frank; Faina, Andres; Risi, Sebastian


    Modular robots oer an important benet in evolutionary robotics, which is to quickly evaluate evolved morphologies and control systems in reality. However, articial evolution of simulated modular robotics is a dicult and time consuming task requiring signicant computational power. While articial...... evolution in virtual creatures has made use of powerful generative encodings, here we investigate how a generative encoding and direct encoding compare for the evolution of locomotion in modular robots when the number of robotic modules changes. Simulating less modules would decrease the size of the genome...

  13. Comparison of a constraint directed search to a genetic algorithm in a scheduling application

    International Nuclear Information System (INIS)

    Abbott, L.


    Scheduling plutonium containers for blending is a time-intensive operation. Several constraints must be taken into account; including the number of containers in a dissolver run, the size of each dissolver run, and the size and target purity of the blended mixture formed from these runs. Two types of algorithms have been used to solve this problem: a constraint directed search and a genetic algorithm. This paper discusses the implementation of these two different approaches to the problem and the strengths and weaknesses of each algorithm

  14. Direct-contact condensers for open-cycle OTEC applications: Model validation with fresh water experiments for structured packings

    Energy Technology Data Exchange (ETDEWEB)

    Bharathan, D.; Parsons, B.K.; Althof, J.A.


    The objective of the reported work was to develop analytical methods for evaluating the design and performance of advanced high-performance heat exchangers for use in open-cycle thermal energy conversion (OC-OTEC) systems. This report describes the progress made on validating a one-dimensional, steady-state analytical computer of fresh water experiments. The condenser model represents the state of the art in direct-contact heat exchange for condensation for OC-OTEC applications. This is expected to provide a basis for optimizing OC-OTEC plant configurations. Using the model, we examined two condenser geometries, a cocurrent and a countercurrent configuration. This report provides detailed validation results for important condenser parameters for cocurrent and countercurrent flows. Based on the comparisons and uncertainty overlap between the experimental data and predictions, the model is shown to predict critical condenser performance parameters with an uncertainty acceptable for general engineering design and performance evaluations. 33 refs., 69 figs., 38 tabs.

  15. Modeling 3D conjugate heat and mass transfer for turbulent air drying of Chilean papaya in a direct contact dryer (United States)

    Lemus-Mondaca, Roberto A.; Vega-Gálvez, Antonio; Zambra, Carlos E.; Moraga, Nelson O.


    A 3D model considering heat and mass transfer for food dehydration inside a direct contact dryer is studied. The k- ɛ model is used to describe turbulent air flow. The samples thermophysical properties as density, specific heat, and thermal conductivity are assumed to vary non-linearly with temperature. FVM, SIMPLE algorithm based on a FORTRAN code are used. Results unsteady velocity, temperature, moisture, kinetic energy and dissipation rate for the air flow are presented, whilst temperature and moisture values for the food also are presented. The validation procedure includes a comparison with experimental and numerical temperature and moisture content results obtained from experimental data, reaching a deviation 7-10 %. In addition, this turbulent k- ɛ model provided a better understanding of the transport phenomenon inside the dryer and sample.

  16. Inter-Comparison of Hydrodynamic Models of Gulf of Khambhat

    Directory of Open Access Journals (Sweden)

    J SatheeshKumar


    Full Text Available The complex seabed contours and geometry of basin lead to a unique tidal pattern along India's Gulf of Khambhat (GoK. Estimation of tidal levels and associated currents in this basin is challenging due to the amplification of tides and intense current magnitudes. In this study, the finite difference based numerical model, Delft3D-FLOW has been set up. Spatially varying bottom roughness parameters have been used to estimate the tidal levels and currents for the entire basin and the results are compared with an earlier work of Sathish Kumar and Balaji (2014 and 2015 based on an alternative finite element based numerical model, Telemac2D. An inter-comparison of model results shows good agreement with each other and with the field measurements. The tidal levels are observed to vary from 2m to more than 10m in the narrowing portion of the gulf while the maximum current velocity is seen as 3m/s.

  17. Comparison between tests and analyses for ground-foundation models

    International Nuclear Information System (INIS)

    Moriyama, Ken-ichi; Hibino, Hirosi; Izumi, Masanori; Kiya, Yukiharu.


    The laboratory tests were carried out on two ground models made of silicone rubber (hard and soft ground models) and a foundation model made of aluminum in order to confirm the embedment effects on soil-structure interaction system experimentally. The detail of the procedure and the results of the test are described in the companion paper. Up till now, the analytical studies on the embedment effect on seismic response of buildings have been performed in recent years and the analysis tools have been used in the seismic design procedure of the nuclear power plant facilities. The embedment effects on soil-structure interaction system are confirmed by the simulation analysis and the verification of analysis tools are investigated through the simulation analysis in this paper. The following conclusions can be drawn from comparison between laboratory test results and analysis results. (1) The effects of embedment, such as increase in the impedance functions and the rotational component of foundation input motions, were clarified by the simulation analyses and laboratory tests. (2) The analysis results of axisymmetric FEM showed good agreement with processed test results by means of the transient response to eliminate the reflected waves and the analysis tools were confirmed experimentally. (3) The excavated portion of the soil affected the foundation input motion rather than the impedance function since there was little difference between the impedance functions obtained by wave propagation theory and those obtained by the axisymmetric FEM and the rotational component of the foundation input motions increased significantly. (J.P.N.)

  18. Direction dependence analysis: A framework to test the direction of effects in linear models with an implementation in SPSS. (United States)

    Wiedermann, Wolfgang; Li, Xintong


    In nonexperimental data, at least three possible explanations exist for the association of two variables x and y: (1) x is the cause of y, (2) y is the cause of x, or (3) an unmeasured confounder is present. Statistical tests that identify which of the three explanatory models fits best would be a useful adjunct to the use of theory alone. The present article introduces one such statistical method, direction dependence analysis (DDA), which assesses the relative plausibility of the three explanatory models on the basis of higher-moment information about the variables (i.e., skewness and kurtosis). DDA involves the evaluation of three properties of the data: (1) the observed distributions of the variables, (2) the residual distributions of the competing models, and (3) the independence properties of the predictors and residuals of the competing models. When the observed variables are nonnormally distributed, we show that DDA components can be used to uniquely identify each explanatory model. Statistical inference methods for model selection are presented, and macros to implement DDA in SPSS are provided. An empirical example is given to illustrate the approach. Conceptual and empirical considerations are discussed for best-practice applications in psychological data, and sample size recommendations based on previous simulation studies are provided.

  19. Functional comparison of annexin V analogues labeled indirectly and directly with iodine-124

    Energy Technology Data Exchange (ETDEWEB)

    Dekker, Bronwen [CRUK/UMIST Dept. of Radiochemical Targeting and Imaging, Paterson Inst. for Cancer Research, M20 4BX Manchester (United Kingdom)]|[Dept. of Instrumentation and Analytical Science, Univ. of Manchester Inst. for Science and Technology (United Kingdom)]. E-mail:; Keen, Heather [CRUK/UMIST Dept. of Radiochemical Targeting and Imaging, Paterson Inst. for Cancer Research, M20 4BX Manchester (United Kingdom)]|[Dept. of Instrumentation and Analytical Science, Univ. of Manchester Inst. for Science and Technology, M60 1QD Manchester (United Kingdom); Shaw, David [CRUK/UMIST Dept. of Radiochemical Targeting and Imaging, Paterson Inst. for Cancer Research, M20 4BX Manchester (United Kingdom)]|[CRUK Dept. of Immunology, Paterson Inst. for Cancer Research, M20 4BX Manchester (United Kingdom); Disley, Lynn [CRUK/UMIST Dept. of Radiochemical Targeting and Imaging, Paterson Inst. for Cancer Research, M20 4BX Manchester (United Kingdom); Hastings, David; Julyan, Peter [CRUK/UMIST Dept. of Radiochemical Targeting and Imaging, Paterson Inst. for Cancer Research, M20 4BX Manchester (United Kingdom)]|[North Western Medical Physics, Christie Hospital NHS Trust, M20 4BX Manchester (United Kingdom); Hadfield, John [School of Environment and Life Sciences, Univ. of Salford, M5 4WT Manchester (United Kingdom); Reader, Andrew [Dept. of Instrumentation and Analytical Science, Univ. of Manchester Inst. for Science and Technology, M60 1QD Manchester (United Kingdom); Allan, Donald [Physics and Electronic Unit, Paterson Inst. for Cancer Research, M20 4BX Manchester (United Kingdom); Watson, Alastair [Dept. of Medicine, Univ of Liverpool (United Kingdom); Zweit, Jamal [CRUK/UMIST Dept. of Radiochemical Targeting and Imaging, Paterson Inst. for Cancer Research, M20 4BX Manchester (United Kingdom)]|[Dept. of Instrumentation and Analytical Science, Univ. of Manchester Inst. for Science and Technology (United Kingdom)]. E-mail:


    We are interested in imaging cell death in vivo using annexin V radiolabeled with {sup 124}I. In this study, [{sup 124}I]4IB-annexin V and [{sup 124}I]4IB-ovalbumin were made using [{sup 124}I]N-hydroxysuccinimidyl-4-iodobenzoate prepared by iododestannylation of N-hydroxysuccinimidyl-4-(tributylstannyl)benzoate. [{sup 124}I]4IB-annexin V binds to phosphatidylserine-coated microtiter plates and apoptotic Jurkat cells and accumulates in hepatic apoptotic lesions in mice treated with anti-Fas antibody, while [{sup 124}I]4IB-ovalbumin does not. In comparison with {sup 124}I-annexin V, [{sup 124}I]4IB-annexin V has a higher rate of binding to phosphatidylserine in vitro, a higher kidney and urine uptake, a lower thyroid and stomach content uptake, greater plasma stability and a lower rate of plasma clearance. Binding of radioactivity to apoptotic cells relative to normal cells in vitro and in vivo appears to be lower for [{sup 124}I]4IB-annexin V than for {sup 124}I-annexin V.

  20. A direct comparison of short-term audiomotor and visuomotor memory. (United States)

    Ward, Amanda M; Loucks, Torrey M; Ofori, Edward; Sosnoff, Jacob J


    Audiomotor and visuomotor short-term memory are required for an important variety of skilled movements but have not been compared in a direct manner previously. Audiomotor memory capacity might be greater to accommodate auditory goals that are less directly related to movement outcome than for visually guided tasks. Subjects produced continuous isometric force with the right index finger under auditory and visual feedback. During the first 10 s of each trial, subjects received continuous auditory or visual feedback. For the following 15 s, feedback was removed but the force had to be maintained accurately. An internal effort condition was included to test memory capacity in the same manner but without external feedback. Similar decay times of ~5-6 s were found for vision and audition but the decay time for internal effort was ~4 s. External feedback thus provides an advantage in maintaining a force level after feedback removal, but may not exclude some contribution from a sense of effort. Short-term memory capacity appears longer than certain previous reports but there may not be strong distinctions in capacity across different sensory modalities, at least for isometric force.

  1. Comparison of Calcium Hydroxide and Bioactive Glass after Direct Pulp Capping in Primary Teeth

    Directory of Open Access Journals (Sweden)

    R. Haghgoo


    Full Text Available Objective: Bioactive glass is often used as a filler material for repair of dental bone defects.In different studies osteogenic potential of this material was proved, but its dentinogenesisproperty is in doubt. The purpose of this study was to evaluate the histological pulp responses of Calcium hydroxide and Bioactive glass placed directly on exposed pulp tissues.Materials and Methods: Twenty teeth to be extracted due to orthodontic reasons were selected. These teeth were divided into two groups and treated with direct pulp capping.Calcium hydroxide was used for 10 teeth and Bioactive glass for 10 teeth. After 60 daysthe teeth were extracted and prepared for histological evaluation. Finally the data was analyzed with exact Fisher test.Results: All teeth treated with Calcium hydroxide showed inflammation. Internal resorption was seen in six teeth, abscess in five teeth and dentinal bridge in two teeth. Inflammationwas seen in three Bioactive glass samples and dentinal bridge in seven teeth, but internal resorption and abscess were not seen.Conclusion: Bioactive glass appears to be superior to Calcium hydroxide as a pulp capping agent in primary teeth.

  2. Comparison of direct deposition and root uptake results after the Fukushima Daiichi Nuclear Power Plant accident

    International Nuclear Information System (INIS)

    Tagami, Keiko; Uchida, Shigeo


    Field horsetail(Equisetum arvense) is a kind of fern, and the fertile shoots are eaten as vegetables in Japan in the spring. Since fern species tend to concentrate radiocaesium from soil, concentrations and distribution patterns of radiocaesium in the fertile shoots are of interest. In this study, distribution and food processing results were compared using samples collected in 2011(n=1) and 2012(n=3); the sample collected in 2011 received direct deposition from the Fukushima Daiichi Nuclear Power Plant accident while those collected in 2012 included radiocaesium mainly taken up from soil. About 200-300 shoots were collected at each sampling time. The 137 Cs concentration in samples collected in 2012 decreased by 100-200 times compared to that in 2011. The radiocaesium distribution patterns in strobili, leaves and stems of 2012 samples were almost the same as those of 2011; however, the patterns were different from those of potassium. The radiocaesium removal percentage by food processing (washing + boiling for 2.5min) was 70% in 2011, while that for 2012 samples was 32-72%; the effect of direct deposition and root uptake was not clear. (author)


    Directory of Open Access Journals (Sweden)

    Masashi Miura


    Full Text Available SUMMARY The use of a “direct PCR” DNA polymerase enables PCR amplification without any prior DNA purification from blood samples due to the enzyme's resistance to inhibitors present in blood components. Such DNA polymerases are now commercially available. We compared the PCR performance of six direct PCR-type DNA polymerases (KOD FX, Mighty Amp, Hemo KlenTaq, Phusion Blood II, KAPA Blood, and BIOTAQ in dried blood eluted from a filter paper with TE buffer. GoTaq Flexi was used as a standard DNA polymerase. PCR performance was evaluated by a nested PCR technique for detecting Plasmodium falciparum genomic DNA in the presence of the blood components. Although all six DNA polymerases showed resistance to blood components compared to the standard Taq polymerase, the KOD FX and BIOTAQ DNA polymerases were resistant to inhibitory blood components at concentrations of 40%, and their PCR performance was superior to that of other DNA polymerases. When the reaction mixture contained a mild detergent, only KOD FX DNA polymerase retained the original amount of amplified product. These results indicate that KOD FX DNA polymerase is the most resistant to inhibitory blood components and/or detergents. Thus, KOD FX DNA polymerase could be useful in serological studies to simultaneously detect antibodies and DNA in eluents for antibodies. KOD FX DNA polymerase is thus not limited to use in detecting malaria parasites, but could also be employed to detect other blood-borne pathogens.

  4. A comparison of direct and indirect laryngoscopes and the ILMA in novice users: a manikin study.

    LENUS (Irish Health Repository)

    Maharaj, C H


    Direct laryngoscopic tracheal intubation using the Macintosh laryngoscope is taught to many healthcare professionals as it is a potentially life-saving procedure. However, it is a difficult skill to acquire and maintain. Several alternative intubation devices exist that may provide a better view of the glottis and require less skill to use. We conducted a prospective, randomised trial of four different laryngoscopes and the ILMA in 30 medical students who had no prior airway management experience. The devices were tested in both normal and cervical immobilisation laryngoscopy scenarios. Following brief didactic instruction, each participant took turns performing laryngoscopy and intubation using each device under direct supervision. Each student was allowed up to three intubation attempts with each device, in each scenario. The Airtraq, McCoy, and the ILMA each demonstrated advantages over the Macintosh laryngoscope. In both the easy and difficult airway scenarios, the Airtraq, McCoy, and the ILMA reduced the number of intubation attempts, and reduced the number of optimisation manoeuvres required. The Airtraq and ILMA reduced the severity of dental trauma in both scenarios. The performance of the other devices studied was more variable. Overall, participants found that only the Airtraq was less difficult to use and they were more confident using it compared to the Macinosh laryngoscope.

  5. A Comparison of Three Second-generation Swirl-Venturi Lean Direct Injection Combustor Concepts (United States)

    Tacina, Kathleen M.; Podboy, Derek P.; He, Zhuohui Joe; Lee, Phil; Dam, Bidhan; Mongia, Hukam


    Three variations of a low emissions aircraft gas turbine engine combustion concept were developed and tested. The concept is a second generation swirl-venturi lean direct injection (SV-LDI) concept. LDI is a lean-burn combustion concept in which the fuel is injected directly into the flame zone. All three variations were based on the baseline 9- point SV-LDI configuration reported previously. The three second generation SV-LDI variations are called the 5-recess configuration, the flat dome configuration, and the 9- recess configuration. These three configurations were tested in a NASA Glenn Research Center medium pressure flametube. All three second generation variations had better low power operability than the baseline 9-point configuration. All three configurations had low NO(sub x) emissions, with the 5-recess configuration generally having slightly lower NO(x) than the flat dome or 9-recess configurations. Due to the limitations of the flametube that prevented testing at pressures above 20 atm, correlation equations were developed for the at dome and 9-recess configurations so that the landing-takeoff NO(sub x) emissions could be estimated. The flat dome and 9-recess landing-takeoff NO(x) emissions are estimated to be 81-88% below the CAEP/6 standards, exceeding the project goal of 75% reduction.

  6. Predicting recycling behaviour: Comparison of a linear regression model and a fuzzy logic model. (United States)

    Vesely, Stepan; Klöckner, Christian A; Dohnal, Mirko


    In this paper we demonstrate that fuzzy logic can provide a better tool for predicting recycling behaviour than the customarily used linear regression. To show this, we take a set of empirical data on recycling behaviour (N=664), which we randomly divide into two halves. The first half is used to estimate a linear regression model of recycling behaviour, and to develop a fuzzy logic model of recycling behaviour. As the first comparison, the fit of both models to the data included in estimation of the models (N=332) is evaluated. As the second comparison, predictive accuracy of both models for "new" cases (hold-out data not included in building the models, N=332) is assessed. In both cases, the fuzzy logic model significantly outperforms the regression model in terms of fit. To conclude, when accurate predictions of recycling and possibly other environmental behaviours are needed, fuzzy logic modelling seems to be a promising technique. Copyright © 2015 Elsevier Ltd. All rights reserved.

  7. Comparison of Model-Based Control Solutions for Severe Riser-Induced Slugs

    DEFF Research Database (Denmark)

    Pedersen, Simon; Jahanshahi, Esmaiel; Yang, Zhenyu


    Control solutions for eliminating severe riser-induced slugs in offshore oil & gas pipeline installations are key topics in offshore Exploration and Production (E&P) processes. This study describes the identification, analysis and control of a low-dimensional control-oriented model of a lab......-scaled slug testing facility. The model is analyzed and used for anti-slug control development for both lowpoint and topside transmitter solutions. For the controlled variables’ comparison it is concluded that the topside pressure transmitter (Pt) is the most difficult output to apply directly for anti-slug...... control due to the inverse response. However, as Pt often is the only accessible measurement on offshore platforms this study focuses on the controller development for both Pt and the lowpoint pressure transmitter (Pb). All the control solutions are based on linear control schemes and the performance...

  8. Markov Chain model for the stochastic behaviors of wind-direction data

    International Nuclear Information System (INIS)

    Masseran, Nurulkamal


    Highlights: • I develop a Markov chain model to describe about the stochastic and probabilistic behaviors of wind direction data. • I describe some of the theoretical arguments regarding the Markov chain model in term of wind direction data. • I suggest a limiting probabilities approach to determine a dominant directions of wind blow. - Abstract: Analyzing the behaviors of wind direction can complement knowledge concerning wind speed and help researchers draw conclusions regarding wind energy potential. Knowledge of the wind’s direction enables the wind turbine to be positioned in such a way as to maximize the total amount of captured energy and optimize the wind farm’s performance. In this paper, first-order and higher-order Markov chain models are proposed to describe the probabilistic behaviors of wind-direction data. A case study is conducted using data from Mersing, Malaysia. The wind-direction data are classified according to an eight-state Markov chain based on natural geographical directions. The model’s parameters are estimated using the maximum likelihood method and the linear programming formulation. Several theoretical arguments regarding the model are also discussed. Finally, limiting probabilities are used to determine a long-run proportion of the wind directions generated. The results explain the dominant direction for Mersing’s wind in terms of probability metrics

  9. Examining a model of dispositional mindfulness, body comparison, and body satisfaction

    NARCIS (Netherlands)

    Dijkstra, Pieternel; Barelds, Dick P. H.

    The present study examined the links between dispositional mindfulness, body comparison, and body satisfaction. It was expected that mindfulness would be associated with less body comparison and more body satisfaction. Two models were tested: one exploring body comparison as a mediator between

  10. Comparison of Predictive Modeling Methods of Aircraft Landing Speed (United States)

    Diallo, Ousmane H.


    Expected increases in air traffic demand have stimulated the development of air traffic control tools intended to assist the air traffic controller in accurately and precisely spacing aircraft landing at congested airports. Such tools will require an accurate landing-speed prediction to increase throughput while decreasing necessary controller interventions for avoiding separation violations. There are many practical challenges to developing an accurate landing-speed model that has acceptable prediction errors. This paper discusses the development of a near-term implementation, using readily available information, to estimate/model final approach speed from the top of the descent phase of flight to the landing runway. As a first approach, all variables found to contribute directly to the landing-speed prediction model are used to build a multi-regression technique of the response surface equation (RSE). Data obtained from operations of a major airlines for a passenger transport aircraft type to the Dallas/Fort Worth International Airport are used to predict the landing speed. The approach was promising because it decreased the standard deviation of the landing-speed error prediction by at least 18% from the standard deviation of the baseline error, depending on the gust condition at the airport. However, when the number of variables is reduced to the most likely obtainable at other major airports, the RSE model shows little improvement over the existing methods. Consequently, a neural network that relies on a nonlinear regression technique is utilized as an alternative modeling approach. For the reduced number of variables cases, the standard deviation of the neural network models errors represent over 5% reduction compared to the RSE model errors, and at least 10% reduction over the baseline predicted landing-speed error standard deviation. Overall, the constructed models predict the landing-speed more accurately and precisely than the current state-of-the-art.

  11. Estimating Am-241 activity in the body: comparison of direct measurements and radiochemical analyses

    International Nuclear Information System (INIS)

    Lynch, Timothy P.; Tolmachev, Sergei Y.; James, Anthony C.


    The assessment of dose and ultimately the health risk from intakes of radioactive materials begins with estimating the amount actually taken into the body. An accurate estimate provides the basis to best assess the distribution in the body, the resulting dose, and ultimately the health risk. This study continues the time-honored practice of evaluating the accuracy of results obtained using in vivo measurement methods and techniques. Results from the radiochemical analyses of the 241Am activity content of tissues and organs from four donors to the United States Transuranium and Uranium Registries were compared to the results from direct measurements of radioactive material in the body performed in vivo and post mortem. Two were whole body donations and two were partial body donations The skeleton was the organ with the highest deposition of 241Am activity in all four cases. The activities ranged from 30 Bq to 300 Bq. The skeletal estimates obtained from measurements over the forehead were within 20% of the radiochemistry results in three cases and differed by 78% in one case. The 241Am lung activity estimates ranged from 1 Bq to 30 Bq in the four cases. The results from the direct measurements were within 40% of the radiochemistry results in 3 cases and within a factor of 3 for the other case. The direct measurement estimates of liver activity ranged from 2 Bq to 60 Bq and were generally lower than the radiochemistry results. The results from this study suggest that the measurement methods and calibration techniques used at the In Vivo Radiobioassay and Research Facility to quantify the activity in the lungs, skeleton and liver are reasonable under the most challenging conditions where there is 241Am activity in multiple organs. These methods and techniques are comparable to those used at other Department of Energy sites. This suggests that the current in vivo methods and calibration techniques provide reasonable estimates of radioactive material in the body. Not

  12. Comparison of Building Energy Modeling Programs: Building Loads

    Energy Technology Data Exchange (ETDEWEB)

    Zhu, Dandan [Tsinghua Univ., Beijing (China); Hong, Tianzhen [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Yan, Da [Tsinghua Univ., Beijing (China); Wang, Chuang [Tsinghua Univ., Beijing (China)


    This technical report presented the methodologies, processes, and results of comparing three Building Energy Modeling Programs (BEMPs) for load calculations: EnergyPlus, DeST and DOE-2.1E. This joint effort, between Lawrence Berkeley National Laboratory, USA and Tsinghua University, China, was part of research projects under the US-China Clean Energy Research Center on Building Energy Efficiency (CERC-BEE). Energy Foundation, an industrial partner of CERC-BEE, was the co-sponsor of this study work. It is widely known that large discrepancies in simulation results can exist between different BEMPs. The result is a lack of confidence in building simulation amongst many users and stakeholders. In the fields of building energy code development and energy labeling programs where building simulation plays a key role, there are also confusing and misleading claims that some BEMPs are better than others. In order to address these problems, it is essential to identify and understand differences between widely-used BEMPs, and the impact of these differences on load simulation results, by detailed comparisons of these BEMPs from source code to results. The primary goal of this work was to research methods and processes that would allow a thorough scientific comparison of the BEMPs. The secondary goal was to provide a list of strengths and weaknesses for each BEMP, based on in-depth understandings of their modeling capabilities, mathematical algorithms, advantages and limitations. This is to guide the use of BEMPs in the design and retrofit of buildings, especially to support China’s building energy standard development and energy labeling program. The research findings could also serve as a good reference to improve the modeling capabilities and applications of the three BEMPs. The methodologies, processes, and analyses employed in the comparison work could also be used to compare other programs. The load calculation method of each program was analyzed and compared to

  13. A Direct Adaptive Control Approach in the Presence of Model Mismatch (United States)

    Joshi, Suresh M.; Tao, Gang; Khong, Thuan


    This paper considers the problem of direct model reference adaptive control when the plant-model matching conditions are violated due to abnormal changes in the plant or incorrect knowledge of the plant's mathematical structure. The approach consists of direct adaptation of state feedback gains for state tracking, and simultaneous estimation of the plant-model mismatch. Because of the mismatch, the plant can no longer track the state of the original reference model, but may be able to track a new reference model that still provides satisfactory performance. The reference model is updated if the estimated plant-model mismatch exceeds a bound that is determined via robust stability and/or performance criteria. The resulting controller is a hybrid direct-indirect adaptive controller that offers asymptotic state tracking in the presence of plant-model mismatch as well as parameter deviations.

  14. Conversational agents for academically productive talk: a comparison of directed and undirected agent interventions

    DEFF Research Database (Denmark)

    Tegos, Stergios; Demetriadis, Stavros N.; Papadopoulos, Pantelis M.


    Conversational agents that draw on the framework of academically productive talk (APT) have been lately shown to be effective in helping learners sustain productive forms of peer dialogue in diverse learning settings. Yet, literature suggests that more research is required on how learners respond...... instead of the dyad (D treatment). The results suggest that although both agent intervention methods can improve students’ learning outcomes and dyad in-task performance, the directed one is more effective than the undirected one in enhancing individual domain knowledge acquisition and explicit reasoning....... Furthermore, findings show that the positive effect of the agent on dyad performance is mediated by the frequency of students’ contributions displaying explicit reasoning, while most students perceive agent involvement favorably....

  15. Comparisons between direct ion storage and thermoluminescence dosimetry individual monitoring systems, and internet reporting

    International Nuclear Information System (INIS)

    Kiuru, A.; Kahilainen, J.; Hyvoenen, H.; Vartiainen, E.


    A new electronic direct ion storage (DIS) dosemeter allows accumulated personal dose equivalent H p (d) at depths of 10 mm and 0.07 mm to be monitored in a few seconds by inserting the dosemeter into a local reader without deleting the accumulated dose. The DIS system meets general requirements on individual monitoring of hospital personnel using ionising radiation. It differs greatly from off-line thermoluminescence dosimetry systems and offers many additional benefits. The non-volatile reading takes only 5 s, is taken as often as needed, and the data are collected into a dose database, where background radiation is subtracted. Individual personnel doses are reported in Intranet as well as on the Internet at regular intervals to the National Regulatory Authorities. (author)

  16. Comparison of transcatheter laser and direct-current shock ablation of endocardium near tricuspid anulus (United States)

    Zhang, Yu-Zhen; Wang, Shi-Wen; Li, Junheng


    Forty to eighty percent of the patients with accessory pathways (APs) manifest themselves by tachyarrhythmias. Many of these patients needed either life-long medical therapy or surgery. In order to avoid the discomfort and expenses in surgical procedures, closed chest percutaneous catheter ablation of APs became a potentially desirable therapeutic approach. Many investigations indicated that ablation of right APs by transcatheter direct current (dc) shock could cause life-threatening arrhythmias, right coronary arterical (RCA) spasm, etc. With the development of transcatheter laser technique, it has been used in drug-incurable arrhythmias. The results show that laser ablation is much safer than surgery and electric shock therapy. The purpose of this study is to explore the effectiveness, advantages, and complications with transcatheter Nd:YAG laser and dc shock in the ablation of right atrioventricular accessory pathways in the atrium near the tricuspid annulus (TA) in 20 dogs.

  17. Optical intensity modulation direct detection versus heterodyne detection: A high-SNR capacity comparison

    KAUST Repository

    Chaaban, Anas


    An optical wireless communications system which employs either intensity-modulation and direct-detection (IM-DD) or heterodyne detection (HD) is considered. IM-DD has lower complexity and cost than HD, but on the other hand, has lower capacity. It is therefore interesting to investigate the capacity gap between the two systems. The main focus of this paper is to investigate this gap at high SNR. Bounds on this gap are established for two cases: between IM-DD and HD, and between IM-DD and an HD-PAM which is an HD system employing pulse-amplitude modulation (PAM). While the gap between IM-DD and HD increases as the signal-to-noise ratio (SNR) increases, the gap between IM-DD and an HD-PAM is upper bounded by a constant at high SNR. © 2015 IEEE.

  18. Comparison of 10 MW superconducting generator topologies for direct-drive wind turbines

    DEFF Research Database (Denmark)

    Liu, Dong; Polinder, Henk; Abrahamsen, Asger Bech


    Large wind turbines of 10 MW or higher power levels are desirable for reducing the cost of energy of offshore wind power conversion. Conventional wind generator systems will be costly if scaled up to 10 MW due to rather large size and weight. Direct drive superconducting generators have been...... proposed to address the problem with generator size, because the electrical machines with superconducting windings are capable of achieving a higher torque density of an electrical machine. However, the topology to be adopted for superconducting wind generators has not yet been settled, since the high...... magnetic field excitation allows for lightweight non-magnetic composite materials for machine cores instead of iron. A topology would probably not be a good option for an offshore wind turbine generator if it demands a far more expensive active material cost than others, even if it has other advantages...

  19. Inferred demand and supply elasticities from a comparison of world oil models

    International Nuclear Information System (INIS)

    Huntington, H.G.


    This paper summarizes the responses of oil supply and demand to prices and income in 11 world oil models that were compared in a recent Energy Modeling Forum (EMF) study. In May 1989, the EMF commenced a study of international oil supplies and demands (hereafter, EMF-11) to compare alternative perspectives on supply and demand issues and how these developments influence the level and direction of world oil prices. In analysing these issues, the EMF-11 working group relied partly upon results from 11 world oil models, using standardized assumptions about oil prices and gross domestic product (GDP). During the study, inferred price elasticities of supply and demand were derived from a comparison of results across different oil price scenarios with the same GDP growth path. Inferred income elasticities of demand were derived from a comparison of results across different economic growth scenarios with the same oil price-path. Together, these estimates summarize several important relationships for understanding oil markets. The first section provides some background on the EMF study and on general trends in the scenarios of interest that help to understand the results. Following sections explain the derivation and qualifications of the inferred estimates, report the results and summarize the key conclusions. (author)

  20. Comparison of Model Output of Wind and Wave Parameters with Spaceborne Altimeter Measurements

    National Research Council Canada - National Science Library

    Hwang, Paul


    .... While comparisons with point measurements from discrete and sparsely distributed wave buoys provide some measure of statistical confidence, the spatial distribution of the modeled wind and wave...

  1. Quantitative comparison of direct phase retrieval algorithms in in-line phase tomography

    International Nuclear Information System (INIS)

    Langer, Max; Cloetens, Peter; Guigay, Jean-Pierre; Peyrin, Francoise


    A well-known problem in x-ray microcomputed tomography is low sensitivity. Phase contrast imaging offers an increase of sensitivity of up to a factor of 10 3 in the hard x-ray region, which makes it possible to image soft tissue and small density variations. If a sufficiently coherent x-ray beam, such as that obtained from a third generation synchrotron, is used, phase contrast can be obtained by simply moving the detector downstream of the imaged object. This setup is known as in-line or propagation based phase contrast imaging. A quantitative relationship exists between the phase shift induced by the object and the recorded intensity and inversion of this relationship is called phase retrieval. Since the phase shift is proportional to projections through the three-dimensional refractive index distribution in the object, once the phase is retrieved, the refractive index can be reconstructed by using the phase as input to a tomographic reconstruction algorithm. A comparison between four phase retrieval algorithms is presented. The algorithms are based on the transport of intensity equation (TIE), transport of intensity equation for weak absorption, the contrast transfer function (CTF), and a mixed approach between the CTF and TIE, respectively. The compared methods all rely on linearization of the relationship between phase shift and recorded intensity to yield fast phase retrieval algorithms. The phase retrieval algorithms are compared using both simulated and experimental data, acquired at the European Synchrotron Radiation Facility third generation synchrotron light source. The algorithms are evaluated in terms of two different reconstruction error metrics. While being slightly less computationally effective, the mixed approach shows the best performance in terms of the chosen criteria.

  2. Direct comparison of amphipod sensitivities to dredged sediments from Spanish ports. (United States)

    Casado-Martinez, M C; Forja, J M; DelValls, T A


    The sensitivity of the benthic amphipod species Ampelisca brevicornis and Corophium volutator to dredged sediments was compared through simultaneous testing on the standard 10 days sediment toxicity test. The results of mortality obtained for 22 harbor sediments sampled at several Spanish ports were studied together with the physico-chemical characteristics of the samples to obtain the incidence of toxicity in terms of dredged material categories and to identify possible differences in the amphipod mortality results when using one or another test species. The results showed a similar incidence of toxicity for medium-high and highly contaminated sediments for both amphipod species, similar to that obtained through the comparison of the chemical concentrations measured in sediments with the single limit values used in Spain for dredged material characterization and management. On the contrary, C. volutator presented a higher mortality and a higher incidence of toxicity when exposed to low and medium-low contaminated sediments, which may have been caused by the lower sensitivity of A. brevicornis when exposed to sediments from its natural environment. When compared to other amphipod species used for whole sediment toxicity assessment, both amphipod species used in this study reported slightly higher sensitivities although these differences could have been associated to the different set of chemical compounds considered when characterizing the sediment samples. In this sense, the amphipod mortality results were better predicted through the use of mean quotients than just by comparing the measured chemical concentrations with the single limit values used in Spain, which indicates that the toxic response of both species was caused by the cocktail of contaminants present in the sediments. Finally, the correlation analysis identified a higher association between A. brevicornis mortality and the metallic contaminants while C. volutator was more correlated with the organic

  3. Direct costs of asthma in Brazil: a comparison between controlled and uncontrolled asthmatic patients

    Directory of Open Access Journals (Sweden)

    L.A. Santos


    Full Text Available Asthma is a common chronic illness that imposes a heavy burden on all aspects of the patient's life, including personal and health care cost expenditures. To analyze the direct cost associated to uncontrolled asthma patients, a cross-sectional study was conducted to determine costs related to patients with uncontrolled and controlled asthma. Uncontrolled patient was defined by daytime symptoms more than twice a week or nocturnal symptoms during two consecutive nights or any limitations of activities, or need for relief rescue medication more than twice a week, and an ACQ score less than 2 points. A questionnaire about direct cost stratification in health services, including emergency room visits, hospitalization, ambulatory visits, and asthma medications prescribed, was applied. Ninety asthma patients were enrolled (45 uncontrolled/45 controlled. Uncontrolled asthmatics accounted for higher health care expenditures than controlled patients, US$125.45 and US$15.58, respectively [emergency room visits (US$39.15 vs US$2.70 and hospitalization (US$86.30 vs US$12.88], per patient over 6 months. The costs with medications in the last month for patients with mild, moderate and severe asthma were US$1.60, 9.60, and 25.00 in the uncontrolled patients, respectively, and US$6.50, 19.00 and 49.00 in the controlled patients. In view of the small proportion of uncontrolled subjects receiving regular maintenance medication (22.2% and their lack of resources, providing free medication for uncontrolled patients might be a cost-effective strategy for the public health system.

  4. In vitro comparison of four different dental X-ray films and direct digital radiography for proximal caries detection. (United States)

    Alkurt, Meryem Torman; Peker, Ilkay; Bala, Oya; Altunkaynak, Bulent


    This study investigated the efficiency of different speeds of conventional intraoral films and a direct digital system for proximal caries detection. In this study, 48 extracted human posterior permanent teeth were used. Conventional bitewing radiographs and direct digital radiographs were obtained from the teeth. Three observers independently assessed 96 proximal surfaces, each observer had 10 years of experience. The presence or absence of caries was scored according to a five-point scale. True caries depth was determined by histological examination. The diagnostic accuracy of each radiographic system was assessed by means of a receiver operating characteristic (ROC) curve analysis. The mean of areas under the ROC curve (Az) was analyzed by pairwise comparison of ROC curve. The interobserver agreement was evaluated by using ANOVA analysis. The statistical analysis of Az scores exhibited no significant difference for the five imaging modalities (p > 0.05). There was no statistically significant difference between interobserver agreements (p > 0.05). The results of this study showed that the diagnostic performance of E- and F-speed films and direct digital radiography are similar for proximal caries detection.

  5. Comparison of the modeling solutions with the hydrogen discharge data

    International Nuclear Information System (INIS)

    Hiskes, J.R.


    With the availability of experimental values for H 2 vibrational population distributions up to v=8 and measured distributions up to v=5 with simultaneous measurements of the H - concentration, it has become possible to test some features of the full-spectrum model of H - generation. The application of the code developed by Gorse et al. to these discharges by the groups at both Bari and at the Ecole Polytechnique has extended the vibrational distribution calculation to include also the H - concentration. Comparing the vibrational population calculated by these two groups at the higher levels, where the onset of H - production occurs, one finds populations for the υ=5 level that are a factor of eight to ten larger than the experimental values. Since these workers have omitted the role of the H 3 + ions known to be present in the discharge, the inclusion of the appropriate S-V process should increase the population discrepancies another factor of two or three. This excess population poses something of a dilemma: Since the Bari code simultaneously reproduces the observed H - concentration but overestimates the vibrational population by a large factor, the standard model of vibrational excitation followed by dissociative attachment is open to question. If measured rather than calculated distributions were used in the H - calculation, the calculated H - concentration would presumably be an order-of-magnitude smaller than the observed value. The measured population distributions taken against the background of the modelling solutions would seem to imply alternate sources of H - production other than dissociative attachment. To examine this problem, we have generated new modelling solutions for comparison with the data of Eenshuistra et al

  6. Comparison of Highly Resolved Model-Based Exposure ... (United States)

    Human exposure to air pollution in many studies is represented by ambient concentrations from space-time kriging of observed values. Space-time kriging techniques based on a limited number of ambient monitors may fail to capture the concentration from local sources. Further, because people spend more time indoors, using ambient concentration to represent exposure may cause error. To quantify the associated exposure error, we computed a series of six different hourly-based exposure metrics at 16,095 Census blocks of three Counties in North Carolina for CO, NOx, PM2.5, and elemental carbon (EC) during 2012. These metrics include ambient background concentration from space-time ordinary kriging (STOK), ambient on-road concentration from the Research LINE source dispersion model (R-LINE), a hybrid concentration combining STOK and R-LINE, and their associated indoor concentrations from an indoor infiltration mass balance model. Using a hybrid-based indoor concentration as the standard, the comparison showed that outdoor STOK metrics yielded large error at both population (67% to 93%) and individual level (average bias between −10% to 95%). For pollutants with significant contribution from on-road emission (EC and NOx), the on-road based indoor metric performs the best at the population level (error less than 52%). At the individual level, however, the STOK-based indoor concentration performs the best (average bias below 30%). For PM2.5, due to the relatively low co

  7. Comparison of Software Models for Energy Savings from Cool Roofs

    Energy Technology Data Exchange (ETDEWEB)

    New, Joshua Ryan [ORNL; Miller, William A [ORNL; Huang, Yu (Joe) [White Box Technologies; Levinson, Ronnen [Lawrence Berkeley National Laboratory (LBNL)


    A web-based Roof Savings Calculator (RSC) has been deployed for the United States Department of Energy as an industry-consensus tool to help building owners, manufacturers, distributors, contractors and researchers easily run complex roof and attic simulations. This tool employs modern web technologies, usability design, and national average defaults as an interface to annual simulations of hour-by-hour, whole-building performance using the world-class simulation tools DOE-2.1E and AtticSim in order to provide estimated annual energy and cost savings. In addition to cool reflective roofs, RSC simulates multiple roof and attic configurations including different roof slopes, above sheathing ventilation, radiant barriers, low-emittance roof surfaces, duct location, duct leakage rates, multiple substrate types, and insulation levels. A base case and energy-efficient alternative can be compared side-by-side to estimate monthly energy. RSC was benchmarked against field data from demonstration homes in Ft. Irwin, California; while cooling savings were similar, heating penalty varied significantly across different simulation engines. RSC results reduce cool roofing cost-effectiveness thus mitigating expected economic incentives for this countermeasure to the urban heat island effect. This paper consolidates comparison of RSC s projected energy savings to other simulation engines including DOE-2.1E, AtticSim, Micropas, and EnergyPlus, and presents preliminary analyses. RSC s algorithms for capturing radiant heat transfer and duct interaction in the attic assembly are considered major contributing factors to increased cooling savings and heating penalties. Comparison to previous simulation-based studies, analysis on the force multiplier of RSC cooling savings and heating penalties, the role of radiative heat exchange in an attic assembly, and changes made for increased accuracy of the duct model are included.

  8. Comparing consumer-directed and agency models for providing supportive services at home. (United States)

    Benjamin, A E; Matthias, R; Franke, T M


    To examine the service experiences and outcomes of low-income Medicaid beneficiaries with disabilities under two different models for organizing home-based personal assistance services: agency-directed and consumer-directed. A survey of a random sample of 1,095 clients, age 18 and over, who receive services in California's In-Home Supportive Services (IHSS) program funded primarily by Medicaid. Other data were obtained from the California Management and Payrolling System (CMIPS). The sample was stratified by service model (agency-directed or consumer-directed), client age (over or under age 65), and severity. Data were collected on client demographics, condition/functional status, and supportive service experience. Outcome measures were developed in three areas: safety, unmet need, and service satisfaction. Factor analysis was used to reduce multiple outcome measures to nine dimensions. Multiple regression analysis was used to assess the effect of service model on each outcome dimension, taking into account the client-provider relationship, client demographics, and case mix. Recipients of IHSS services as of mid-1996 were interviewed by telephone. The survey was conducted in late 1996 and early 1997. On various outcomes, recipients in the consumer-directed model report more positive outcomes than those in the agency model, or they report no difference. Statistically significant differences emerge on recipient safety, unmet needs, and service satisfaction. A family member present as a paid provider is also associated with more positive reported outcomes within the consumer-directed model, but model differences persist even when this is taken into account. Although both models have strengths and weaknesses, from a recipient perspective the consumer-directed model is associated with more positive outcomes. Although health professionals have expressed concerns about the capacity of consumer direction to assure quality, particularly with respect to safety, meeting unmet

  9. Comparison of direct measurement methods for headset noise exposure in the workplace

    Directory of Open Access Journals (Sweden)

    Flora G Nassrallah


    Full Text Available The measurement of noise exposure from communication headsets poses a methodological challenge. Although several standards describe methods for general noise measurements in occupational settings, these are not directly applicable to noise assessments under communication headsets. For measurements under occluded ears, specialized methods have been specified by the International Standards Organization (ISO 11904 such as the microphone in a real ear and manikin techniques. Simpler methods have also been proposed in some national standards such as the use of general purpose artificial ears and simulators in conjunction with single number corrections to convert measurements to the equivalent diffuse field. However, little is known about the measurement agreement between these various methods and the acoustic manikin technique. Twelve experts positioned circum-aural, supra-aural and insert communication headsets on four different measurement setups (Type 1, Type 2, Type 3.3 artificial ears, and acoustic manikin. Fit-refit measurements of four audio communication signals were taken under quiet laboratory conditions. Data were transformed into equivalent diffuse-field sound levels using third-octave procedures. Results indicate that the Type 1 artificial ear is not suited for the measurement of sound exposure under communication headsets, while Type 2 and Type 3.3 artificial ears are in good agreement with the acoustic manikin technique. Single number corrections were found to introduce a large measurement uncertainty, making the use of the third-octave transformation preferable.

  10. A Comparison of Direct and Two-Stage Transportation of Patients to Hospital in Poland

    Directory of Open Access Journals (Sweden)

    Anna Rosiek


    Full Text Available Background: The rapid international expansion of telemedicine reflects the growth of technological innovations. This technological advancement is transforming the way in which patients can receive health care. Materials and Methods: The study was conducted in Poland, at the Department of Cardiology of the Regional Hospital of Louis Rydygier in Torun. The researchers analyzed the delay in the treatment of patients with acute coronary syndrome. The study was conducted as a survey and examined 67 consecutively admitted patients treated invasively in a two-stage transport system. Data were analyzed statistically. Results: Two-stage transportation does not meet the timeframe guidelines for the treatment of patients with acute myocardial infarction. Intervals for the analyzed group of patients were statistically significant (p < 0.0001. Conclusions: Direct transportation of the patient to a reference center with interventional cardiology laboratory has a significant impact on reducing in-hospital delay in case of patients with acute coronary syndrome. Perspectives: This article presents the results of two-stage transportation of the patient with acute coronary syndrome. This measure could help clinicians who seek to assess time needed for intervention. It also shows how time from the beginning of pain in chest is important and may contribute to patient disability, death or well-being.

  11. Comparison of Direct Trocar Entry and Veress Needle Entry in Laparoscopic Bariatric Surgery: Randomized Controlled Trial. (United States)

    Ertugrul, Ismail; Kayaalp, Cuneyt; Yagci, Mehmet Ali; Sumer, Fatih; Karagul, Servet; Tolan, Kerem


    We aimed to compare the direct trocar insertion (DTI) and Veress needle insertion (VNI) techniques in laparoscopic bariatric surgery. Eighty-one patients scheduled for bariatric surgery at Inonu University, Malatya, Turkey, were included in this study. In 39 patients, a bladed retractable nonoptical trocar was used for DTI, and VNI was performed in 42 patients. Intraoperative access-related parameters were compared. Data were analyzed with Student's t and chi-squared tests. A P value of Successful entry rates in the first attempt, CO2 consumptions, failed attempt rates, and overall intraoperative complication rates were similar. However, in the DTI group, 2 patients had mesenteric injuries, and 1 of them required conversion to open surgery due to the mesenteric hemorrhage. DTI in obese patients significantly shortens the entry time, but there can be severe complications with DTI when a nonoptical bladed trocar is used blindly. Actually, neither method can be recommended for entry into the abdomen in this population based on our results. If the surgeon has to choose a nonoptical trocar in bariatric surgery, preference for the VNI technique instead of the DTI technique is safer.

  12. GPS scintillation effects associated with polar cap patches and substorm auroral activity: direct comparison

    Directory of Open Access Journals (Sweden)

    Jin Yaqi


    Full Text Available We directly compare the relative GPS scintillation levels associated with regions of enhanced plasma irregularities called auroral arcs, polar cap patches, and auroral blobs that frequently occur in the polar ionosphere. On January 13, 2013 from Ny-Ålesund, several polar cap patches were observed to exit the polar cap into the auroral oval, and were then termed auroral blobs. This gave us an unprecedented opportunity to compare the relative scintillation levels associated with these three phenomena. The blobs were associated with the strongest phase scintillation (σϕ, followed by patches and arcs, with σϕ up to 0.6, 0.5, and 0.1 rad, respectively. Our observations indicate that most patches in the nightside polar cap have produced significant scintillations, but not all of them. Since the blobs are formed after patches merged into auroral regions, in space weather predictions of GPS scintillations, it will be important to enable predictions of patches exiting the polar cap.

  13. Comparison of the diagnostic accuracy of direct digital radiography system, filtered images, and subtraction radiography

    Directory of Open Access Journals (Sweden)

    Wilton Mitsunari Takeshita


    Full Text Available Background: To compare the diagnostic accuracy of three different imaging systems: Direct digital radiography system (DDR-CMOS, four types of filtered images, and a priori and a posteriori registration of digital subtraction radiography (DSR in the diagnosis of proximal defects. Materials and Methods: The teeth were arranged in pairs in 10 blocks of vinyl polysiloxane, and proximal defects were performed with drills of 0.25, 0.5, and 1 mm diameter. Kodak RVG 6100 sensor was used to capture the images. A posteriori DSR registrations were done with Regeemy 0.2.43 and subtraction with Image Tool 3.0. Filtered images were obtained with Kodak Dental Imaging 6.1 software. Images (n = 360 were evaluated by three raters, all experts in dental radiology. Results: Sensitivity and specificity of the area under the receiver operator characteristic (ROC curve (Az were higher for DSR images with all three drills (Az = 0.896, 0.979, and 1.000 for drills 0.25, 0.5, and 1 mm, respectively. The highest values were found for 1-mm drills and the lowest for 0.25-mm drills, with negative filter having the lowest values of all (Az = 0.631. Conclusion: The best method of diagnosis was by using a DSR. The negative filter obtained the worst results. Larger drills showed the highest sensitivity and specificity values of the area under the ROC curve.

  14. Comparison of inoculant and indigenous rhizobial dinitrogen fixation in cowpeas by direct nitrogen-15 analyses

    International Nuclear Information System (INIS)

    ElHassan, G.A.; Focht, D.D.


    Soil that contained 15 N enriched organic matter (0.461 % 15 N) was used to determine competitiveness of six strains at different logarithmic inoculum densities against indigenous rhizobia and against a previous surviving inoculant (strain P132). Analyses of N content of plant tissues by direct 15 N technique showed that cowpeas (Vigna unguiculata L. Walp.) were capable of deriving 60 to 98% of shoot N from N 2 fixation. The two fast-growing strains (176A26 and 176A28) were poorer competitors and fixed less N 2 compared to the other slow-growing strains. Inoculum density had no effect upon yield response of cowpeas, but inoculation with strains P132, 401, and 22A1 effected greater seed yield, shoot dry matter, total N, and percentage of N derived from fixation (86-98%) than other strains and the uninoculated control (60-73%). By contrast, N 2 fixation and yield parameters in inoculated cowpeas were not significantly different from inoculated controls that contained residual P132 from a previous inoculum study. The higher hydrogen uptake (Hup) efficiency of nodules containing residual P132 (98 ± 2%) facilitated presumptive identification of P132 (100% ± 0 Hup efficiency axenically) as the surviving and infecting inoculant strain since nodules infected by indigenous rhizobia had lower Hup efficiencies (88 ± 2%)

  15. Comparison of directed and weighted co-occurrence networks of six languages (United States)

    Gao, Yuyang; Liang, Wei; Shi, Yuming; Huang, Qiuling


    To study commonalities and differences among different languages, we select 100 reports from the documents of the United Nations, each of which was written in Arabic, Chinese, English, French, Russian and Spanish languages, separately. Based on these corpora, we construct 6 weighted and directed word co-occurrence networks. Besides all the networks exhibit scale-free and small-world features, we find several new non-trivial results, including connections among English words are denser, and the expression of English language is more flexible and powerful; the connection way among Spanish words is more stringent and this indicates that the Spanish grammar is more rigorous; values of many statistical parameters of the French and Spanish networks are very approximate and this shows that these two languages share many commonalities; Arabic and Russian words have many varieties, which result in rich types of words and a sparse connection among words; connections among Chinese words obey a more uniform distribution, and one inclines to use the least number of Chinese words to express the same complex information as those in other five languages. This shows that the expression of Chinese language is quite concise. In addition, several topics worth further investigating by the complex network approach have been observed in this study.

  16. Comparison of Propane and Methane Performance and Emissions in a Turbocharged Direct Injection Dual Fuel Engine

    Energy Technology Data Exchange (ETDEWEB)

    Gibson, C. M.; Polk, A. C.; Shoemaker, N. T.; Srinivasan, K. K.; Krishnan, S. R.


    With increasingly restrictive NO x and particulate matter emissions standards, the recent discovery of new natural gas reserves, and the possibility of producing propane efficiently from biomass sources, dual fueling strategies have become more attractive. This paper presents experimental results from dual fuel operation of a four-cylinder turbocharged direct injection (DI) diesel engine with propane or methane (a natural gas surrogate) as the primary fuel and diesel as the ignition source. Experiments were performed with the stock engine control unit at a constant speed of 1800 rpm, and a wide range of brake mean effective pressures (BMEPs) (2.7-11.6 bars) and percent energy substitutions (PESs) of C 3 H 8 and CH 4. Brake thermal efficiencies (BTEs) and emissions (NO x, smoke, total hydrocarbons (THCs), CO, and CO 2) were measured. Maximum PES levels of about 80-95% with CH 4 and 40-92% with C 3 H 8 were achieved. Maximum PES was limited by poor combustion efficiencies and engine misfire at low loads for both C 3 H 8 and CH 4, and the onset of knock above 9 bar BMEP for C 3 H 8. While dual fuel BTEs were lower than straight diesel BTEs at low loads, they approached diesel BTE values at high loads. For dual fuel operation, NO x and smoke reductions (from diesel values) were as high as 66-68% and 97%, respectively, but CO and THC emissions were significantly higher with increasing PES at all engine loads

  17. Mimicking the Nanostructure of Bone: Comparison of Polymeric Process-Directing Agents

    Directory of Open Access Journals (Sweden)

    Laurie B. Gower


    Full Text Available The nanostructure of bone has been replicated using a polymer-induced liquid-precursor (PILP mineralization process. This polymer-mediated crystallization process yields intrafibrillar mineralization of collagen with uniaxially-oriented hydroxyapatite crystals. The process-directing agent, an anionic polymer which we propose mimics the acidic non-collagenous proteins associated with bone formation, sequesters calcium and phosphate ions to form amorphous precursor droplets that can infiltrate the interstices of collagen fibrils. In search of a polymeric agent that produces the highest mineral content in the shortest time, we have studied the influence of various acidic polymers on the in vitro mineralization of collagen scaffolds via the PILP process. Among the polymers investigated were poly-L-aspartic acid (PASP, poly-L-glutamic acid (PGLU, polyvinylphosphonic acid (PVPA, and polyacrylic acid (PAA. Our data indicate that PASP and the combination of PGLU/PASP formed stable mineralization solutions, and yielded nano-structured composites with the highest mineral content. Such studies contribute to our goal of preparing biomimetic bone graft substitutes with composition and structure that mimic bone.

  18. Construction of health preferences: a comparison of direct value assessment and personal narratives. (United States)

    Kerstholt, José H; van der Zwaard, Fred; Bart, Hans; Cremers, Anita


    Most terminally ill patients prefer to die at home rather than at an institution. However, patients are often insufficiently aware of the downsides of staying at home, which signals a need for effective decision aids. The main purpose of the present study was to compare indirect methods of value elicitation (personal narratives["stories"] in text or video) with a direct method (assessment of the subjective importance of each attribute). The authors asked 183 participants to evaluate 3 possible places to die: home, hospice, and nursing home. The participants received 1 of 3 value elicitation methods. The main dependent variable was participants' evaluations of the choice options before and after value elicitation, measured on a 100-point scale. A shift occurred between pre- and posttest, F(4, 342) = 4.11, P = 0.003, only with the indirect methods. When text and videos were used, participants became more positive about a hospice (text: 41.9 to 49.1; video: 52.9 to 60.3). In the video condition, participants also became more positive about a nursing home (from 20.9 to 24.9). Stories have more impact in shaping people's preferences than merely asking for an assessment of attribute importance. The most straightforward explanation for this effect is that stories, particularly when presented in video, provide a better image of potential consequences.

  19. A Comparison of Combustion Dynamics for Multiple 7-Point Lean Direct Injection Combustor Configurations (United States)

    Tacina, K. M.; Hicks, Y. R.


    The combustion dynamics of multiple 7-point lean direct injection (LDI) combustor configurations are compared. LDI is a fuel-lean combustor concept for aero gas turbine engines in which multiple small fuel-air mixers replace one traditionally-sized fuel-air mixer. This 7-point LDI configuration has a circular cross section, with a center (pilot) fuel-air mixer surrounded by six outer (main) fuel-air mixers. Each fuel-air mixer consists of an axial air swirler followed by a converging-diverging venturi. A simplex fuel injector is inserted through the center of the air swirler, with the fuel injector tip located near the venturi throat. All 7 fuel-air mixers are identical except for the swirler blade angle, which varies with the configuration. Testing was done in a 5-atm flame tube with inlet air temperatures from 600 to 800 F and equivalence ratios from 0.4 to 0.7. Combustion dynamics were measured using a cooled PCB pressure transducer flush-mounted in the wall of the combustor test section.

  20. Utility of the Hebb–Williams Maze Paradigm for Translational Research in Fragile X Syndrome: A Direct Comparison of Mice and Humans (United States)

    Boutet, Isabelle; Collin, Charles A.; MacLeod, Lindsey S.; Messier, Claude; Holahan, Matthew R.; Berry-Kravis, Elizabeth; Gandhi, Reno M.; Kogan, Cary S.


    To generate meaningful information, translational research must employ paradigms that allow extrapolation from animal models to humans. However, few studies have evaluated translational paradigms on the basis of defined validation criteria. We outline three criteria for validating translational paradigms. We then evaluate the Hebb–Williams maze paradigm (Hebb and Williams, 1946; Rabinovitch and Rosvold, 1951) on the basis of these criteria using Fragile X syndrome (FXS) as model disease. We focused on this paradigm because it allows direct comparison of humans and animals on tasks that are behaviorally equivalent (criterion #1) and because it measures spatial information processing, a cognitive domain for which FXS individuals and mice show impairments as compared to controls (criterion #2). We directly compared the performance of affected humans and mice across different experimental conditions and measures of behavior to identify which conditions produce comparable patterns of results in both species. Species differences were negligible for Mazes 2, 4, and 5 irrespective of the presence of visual cues, suggesting that these mazes could be used to measure spatial learning in both species. With regards to performance on the first trial, which reflects visuo-spatial problem solving, Mazes 5 and 9 without visual cues produced the most consistent results. We conclude that the Hebb–Williams mazes paradigm has the potential to be utilized in translational research to measure comparable cognitive functions in FXS humans and animals (criterion #3). PMID:29643767

  1. Direct comparison of photoemission spectroscopy and in situ Kelvin probe work function measurements on indium tin oxide films

    International Nuclear Information System (INIS)

    Beerbom, M.M.; Laegel, B.; Cascio, A.J.; Doran, B.V.; Schlaf, R.


    The work function of commercially available indium tin oxide (ITO) films on glass substrates was measured using photoemission spectroscopy (PES) and ultra-high vacuum (UHV) Kelvin probe in direct comparison. Absolute Kelvin probe work function values were determined via calibration of the measured contact potential difference (CPD) using an in situ sputtered Au reference sample. The Kelvin probe data confirmed that ultraviolet photoemission spectroscopy (UPS) measurements change the work function of ITO surfaces previously exposed to ambient environment, when measured without in situ surface cleaning procedures. The results also demonstrate that both Kelvin probe and PES yield virtually identical work function values, as long as the Kelvin probe data are calibrated against a known standard. As a consequence, previously reported higher work function values determined with Kelvin probe as compared to values obtained with UPS on similar samples are likely related to a photochemically generated surface dipole during UPS measurements. Comparison between Kelvin probe and low intensity X-ray photoemission spectroscopy (LIXPS) work function measurements demonstrated that accurate work function measurements on ITO previously exposed to the ambient are possible with PES

  2. Last interglacial temperature evolution – a model inter-comparison

    Directory of Open Access Journals (Sweden)

    P. Bakker


    Full Text Available There is a growing number of proxy-based reconstructions detailing the climatic changes that occurred during the last interglacial period (LIG. This period is of special interest, because large parts of the globe were characterized by a warmer-than-present-day climate, making this period an interesting test bed for climate models in light of projected global warming. However, mainly because synchronizing the different palaeoclimatic records is difficult, there is no consensus on a global picture of LIG temperature changes. Here we present the first model inter-comparison of transient simulations covering the LIG period. By comparing the different simulations, we aim at investigating the common signal in the LIG temperature evolution, investigating the main driving forces behind it and at listing the climate feedbacks which cause the most apparent inter-model differences. The model inter-comparison shows a robust Northern Hemisphere July temperature evolution characterized by a maximum between 130–125 ka BP with temperatures 0.3 to 5.3 K above present day. A Southern Hemisphere July temperature maximum, −1.3 to 2.5 K at around 128 ka BP, is only found when changes in the greenhouse gas concentrations are included. The robustness of simulated January temperatures is large in the Southern Hemisphere and the mid-latitudes of the Northern Hemisphere. For these regions maximum January temperature anomalies of respectively −1 to 1.2 K and −0.8 to 2.1 K are simulated for the period after 121 ka BP. In both hemispheres these temperature maxima are in line with the maximum in local summer insolation. In a number of specific regions, a common temperature evolution is not found amongst the models. We show that this is related to feedbacks within the climate system which largely determine the simulated LIG temperature evolution in these regions. Firstly, in the Arctic region, changes in the summer sea-ice cover control the evolution of LIG winter

  3. Comparison of quantitative real-time PCR and direct immunofluorescence for the detection of Pneumocystis jirovecii. (United States)

    Moodley, Bhavani; Tempia, Stefano; Frean, John Andrew


    Pneumocystis pneumonia (PCP) is a serious risk for HIV-positive patients. Asymptomatic infection or colonisation with P. jirovecii has been shown to occur frequently. PCR assays frequently identify such cases, due to their high sensitivity. Quantitative real-time PCR (qPCR) gene copy number cut-off values have been suggested to differentiate colonisation and infection; these need to be standardised for routine use. We compared the results of qPCR with an immunofluorescence assay (IFA) to determine a specific cut-off value. From March 2005 through June 2009, induced sputum specimens were collected from adult patients who were clinically suspected of having PCP, at the Chris Hani Baragwanath Hospital in Gauteng, South Africa. Laboratory diagnosis of PCP was done by a conventional direct IFA and a qPCR assay. A receiver operating characteristic (ROC) analysis was performed to determine a suitable copy number cut-off value. P. jirovecii was identified in 51% (156/305) and 67% (204/305) of specimens using IFA and qPCR, respectively. The cut-off value for the qPCR that best predicted the IFA results was 78 copies/5 μl (area under ROC curve 0.92). The sensitivity and specificity of qPCR using this cut-off was 94.6% and 89.1%, respectively, compared with the IFA. The results of the ROC curve analysis indicate an excellent predictive value of the qPCR using the proposed cut-off. However, the IFA test is an imperfect gold standard and so this cut-off should not be used in isolation; clinical data should also contribute to the interpretation of the qPCR result.

  4. Comparison of the direct and indirect effects of epinephrine on hepatic glucose production. (United States)

    Chu, C A; Sindelar, D K; Neal, D W; Allen, E J; Donahue, E P; Cherrington, A D


    To determine the extent to which the effect of a physiologic increment in epinephrine (EPI) on glucose production (GP) arises indirectly from its action on peripheral tissues (muscle and adipose tissue), epinephrine was infused intraportally (EPI po) or peripherally (EPI pe) into 18-h-fasted conscious dogs maintained on a pancreatic clamp. Arterial EPI levels in EPI po and EPI pe groups rose from 97 +/- 29 to 107 +/- 37 and 42 +/- 12 to 1,064 +/- 144 pg/ml, respectively. Hepatic sinusoidal EPI levels in EPI po and EPI pe were indistinguishable (561 +/- 84 and 568 +/- 75 pg/ml, respectively). During peripheral epinephrine infusion, GP increased from 2.2 +/- 0.1 to 5.1 +/- 0.2 mg/kg x min (10 min). In the presence of the same rise in sinusoidal EPI, but with no rise in arterial EPI (during portal EPI infusion), GP increased from 2.1 +/- 0.1 to 3.8 +/- 0.6 mg/kg x min. Peripheral EPI infusion increased the maximal gluconeogenic rate from 0.7 +/- 0.4 to 1.8 +/- 0.5 mg/ kg x min. Portal EPI infusion did not change the maximal gluconeogenic rate. The estimated initial increase in glycogenolysis was approximately 1.7 and 2.3 mg/kg x min in the EPI pe and EPI po groups, respectively. Gluconeogenesis was responsible for 60% of the overall increase in glucose production stimulated by the increase in plasma epinephrine (EPI pe). Elevation of sinusoidal EPI per se had no direct gluconeogenic effect on the liver, thus its effect on glucose production was solely attributable to an increase in glycogenolysis. Lastly, the gluconeogenic effects of EPI markedly decreased (60-80%) its overall glycogenolytic action on the liver.

  5. Comparison of PCR, Culture, and Direct Fluorescent-Antibody Testing for Detection of Bordetella pertussis (United States)

    Loeffelholz, Mike J.; Thompson, Curt J.; Long, Karla S.; Gilchrist, Mary J. R.


    We prospectively compared the performance of culture, direct fluorescent-antibody testing (DFA), and an in-house-developed PCR test targeting the repeated insertion sequence IS481 for the detection of Bordetella pertussis in nasopharyngeal swab specimens. We tested 319 consecutive paired specimens on which all three tests were performed. A total of 59 specimens were positive by one or more tests. Of these, 5 were positive by all three tests, 2 were positive by culture and PCR, 16 were positive by PCR and DFA, 28 were positive by PCR only, and 8 were positive by DFA only. Any specimen positive by culture was considered to be a true positive, as were specimens positive by both PCR and DFA. Specimens positive only by PCR or DFA were considered discrepant, and their status was resolved by review of patient histories. Patients with symptoms meeting the Centers for Disease Control and Prevention clinical case definition for pertussis and who had a specimen positive by PCR or DFA were considered to have true B. pertussis infections. Of the 28 patients positive by PCR only, 20 met the clinical case definition for pertussis, while 3 of the 8 patients positive by DFA only met the clinical case definition. After resolution of the status of discrepant specimens, the sensitivity, specificity, positive predictive value, and negative predictive value were 15.2, 100, 100, and 87.5%, respectively, for culture; 93.5, 97.1, 84.3, and 98.9%, respectively, for PCR; and 52.2, 98.2, 82.8, and 92.4%, respectively, for DFA. The actual positive predictive value of PCR was probably greater, as several PCR-positive patients who did not meet the clinical case definition had symptoms consistent with typical or atypical pertussis. PCR is a sensitive and specific method for the detection of B. pertussis. PMID:10449467

  6. Comparison of latex agglutination and immunofluorescence for direct Lancefield grouping of streptococci from blood cultures. (United States)

    Shlaes, D M; Toossi, Z; Patel, A


    Simulated positive blood cultures with 84 known stock strains of streptococci were used to comparatively evaluate the direct identification of these organisms by fluorescein-tagged antibody staining (immunofluorescence [IF]) and latex agglutination (LA). IF was not evaluated for Lancefield group D strains (a total of 81 strains tested) and had 89% sensitivity and 91% specificity. IF was least sensitive for the identification of Lancefield group F, in which three of seven strains showed no fluorescence with the group F reagent. Since LA was more convenient and revealed comparable sensitivities and specificities on 84 simulated cultures, we tested this procedure using an additional 29 fresh positive clinical blood cultures, for a total of 113 cultures tested by this technique. Of 11 Streptococcus pneumoniae strains, 9 reacted with the LA group C reagent, a problem not observed with IF. However, all these strains were identified by a rapid modified bile solubility test. Of the 12 Streptococcus faecalis strains, 4 were falsely negative with the group D reagent, but all were correctly identified by a rapid litmus milk reduction test. Of 12 group A strains, 1 was not detected. Of all 113 strains tested by LA, eliminating S. faecalis and S. pneumoniae, the sensitivity and specificity were 97 and 98%, respectively. LA was simple and reliable in the rapid identification of streptococci from blood cultures and appeared to be preferable to IF. When LA is used, the group D reagent should not be used, and all samples reacting with the group C reagent should be tested by a modified rapid bile solubility test to exclude S. pneumoniae.

  7. Direct comparison of the four aldehyde oxidase enzymes present in mouse gives insight into their substrate specificities.

    Directory of Open Access Journals (Sweden)

    Gökhan Kücükgöze

    Full Text Available Mammalian aldehyde oxidases (AOXs are molybdo-flavoenzymes which are present in many tissues in various mammalian species, including humans and rodents. Different species contain a different number of AOX isoforms. In particular, the reasons why mammals other than humans express a multiplicity of tissue-specific AOX enzymes is unknown. In mouse, the isoforms mAOX1, mAOX3, mAOX4 and mAOX2 are present. We previously established a codon-optimized heterologous expression systems for the mAOX1-4 isoforms in Escherichia coli that gives yield to sufficient amounts of active protein for kinetic characterizations and sets the basis in this study for site-directed mutagenesis and structure-function studies. A direct and simultaneous comparison of the enzymatic properties and characteristics of the four enzymes on a larger number of substrates has never been performed. Here, thirty different structurally related aromatic, aliphatic and N-heterocyclic compounds were used as substrates, and the kinetic parameters of all four mAOX enzymes were directly compared. The results show that especially mAOX4 displays a higher substrate selectivity, while no major differences between mAOX1, mAOX2 and mAOX3 were identified. Generally, mAOX1 was the enzyme with the highest catalytic turnover for most substrates. To understand the factors that contribute to the substrate specificity of mAOX4, site-directed mutagenesis was applied to substitute amino acids in the substrate-binding funnel by the ones present in mAOX1, mAOX3, and mAOX2. An increase in activity was obtained by the amino acid exchange M1088V in the active site identified to be specific for mAOX4, to the amino acid identified in mAOX3.

  8. 75 FR 61655 - Airworthiness Directives; Piper Aircraft, Inc. Model PA-28-161 Airplanes (United States)


    ..., Inc. Model PA-28-161 Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... airworthiness directive (AD) for all Piper Aircraft, Inc. (Piper) Model PA-28-161 airplanes equipped with.... Piper Model PA-28-161 airplanes modified by STC No. SA03303AT have a similar unsafe design feature that...

  9. Single-layer skull approximations perform well in transcranial direct current stimulation modeling

    NARCIS (Netherlands)

    Rampersad, S.M.; Stegeman, D.F.; Oostendorp, T.F.


    In modeling the effect of transcranial direct current stimulation, the representation of the skull is an important factor. In a spherical model, we compared a realistic skull modeling approach, in which the skull consisted of three isotropic layers, to anisotropic and isotropic single-layer

  10. 76 FR 27237 - Airworthiness Directives; Empresa Brasileira de Aeronautica S.A. (EMBRAER) Model ERJ 170... (United States)


    ... Airworthiness Directives; Empresa Brasileira de Aeronautica S.A. (EMBRAER) Model ERJ 170 Airplanes; and Model... adding the following new AD: 2011-10-03 Empresa Brasileira de Aeronautica S.A. (EMBRAER): Amendment 39... applies to Empresa Brasileira de Aeronautica S.A. (EMBRAER) Model ERJ 170-100 LR, -100 STD, -100 SE, and...

  11. Direct and Indirect Effects of Parental Influence upon Adolescent Alcohol Use: A Structural Equation Modeling Analysis (United States)

    Kim, Young-Mi; Neff, James Alan


    A model incorporating the direct and indirect effects of parental monitoring on adolescent alcohol use was evaluated by applying structural equation modeling (SEM) techniques to data on 4,765 tenth-graders in the 2001 Monitoring the Future Study. Analyses indicated good fit of hypothesized measurement and structural models. Analyses supported both…

  12. Comparison of blade-strike modeling results with empirical data

    Energy Technology Data Exchange (ETDEWEB)

    Ploskey, Gene R. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Carlson, Thomas J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)


    This study is the initial stage of further investigation into the dynamics of injury to fish during passage through a turbine runner. As part of the study, Pacific Northwest National Laboratory (PNNL) estimated the probability of blade strike, and associated injury, as a function of fish length and turbine operating geometry at two adjacent turbines in Powerhouse 1 of Bonneville Dam. Units 5 and 6 had identical intakes, stay vanes, wicket gates, and draft tubes, but Unit 6 had a new runner and curved discharge ring to minimize gaps between the runner hub and blades and between the blade tips and discharge ring. We used a mathematical model to predict blade strike associated with two Kaplan turbines and compared results with empirical data from biological tests conducted in 1999 and 2000. Blade-strike models take into consideration the geometry of the turbine blades and discharges as well as fish length, orientation, and distribution along the runner. The first phase of this study included a sensitivity analysis to consider the effects of difference in geometry and operations between families of turbines on the strike probability response surface. The analysis revealed that the orientation of fish relative to the leading edge of a runner blade and the location that fish pass along the blade between the hub and blade tip are critical uncertainties in blade-strike models. Over a range of discharges, the average prediction of injury from blade strike was two to five times higher than average empirical estimates of visible injury from shear and mechanical devices. Empirical estimates of mortality may be better metrics for comparison to predicted injury rates than other injury measures for fish passing at mid-blade and blade-tip locations.

  13. Modeling directional effects in land surface temperature derived from geostationary satellite data

    DEFF Research Database (Denmark)

    Rasmussen, Mads Olander

    This PhD-thesis investigates the directional effects in land surface temperature (LST) estimates from the SEVIRI sensor onboard the Meteosat Second Generation (MSG) satellites. The directional effects are caused by the land surface structure (i.e. tree size and shape) interacting with the changing...... the illumination geometry changes both over the course of the day and with the seasons. In the present study, the directional effects are assessed at different scales using a modeling approach. The model applied, the Modified Geometry Projection (MGP) model, represents the surface as a composite of four components...... that the magnitude of the directional effects mainly depends on the tree cover, with moderate tree covers (20-40 %) causing the largest directional effects but with significant effects also at much sparser tree cover. The magnitude is also highly dependent on the temperature difference between the surface components...

  14. Dichroic directional excitation of surface plasmon based on an integer-programming model. (United States)

    Chen, Quansheng; Sun, Yuanchao; Wang, Yueke


    A silver film perforated with two subwavelength uniform slits is proposed for dichroic directional excitation of surface plasmon polaritons (SPPs). Under backside oblique illumination, the SPPs for two work wavelengths can propagate along the two opposite directions or in the same direction. Based on SPP interference, an integer-programming model is established for dichroic directional excitation of SPPs. The branch and bound method is introduced to find the optimal solutions for the integer-programming model, and therefore, the parameters of the structure and illumination angles can be obtained. The field distribution of the structure is investigated by using the finite-difference time-domain method (FDTD) to verify our design. Our theoretical model can achieve dichroic directional excitation of SPPs, simultaneously.

  15. Comparison of the precision of three commonly used GPS models

    Directory of Open Access Journals (Sweden)

    E Chavoshi


    farming operations as well as the efficiency of the work done in different situations. Materials and Methods: In this study, three commonly used GPS models belong to GARMIN CO. were selected for comparison. This company is the world biggest manufacturer of GPS device. Three models include eTrex VISTA, MAP 60 csx and MAP 78s that in recent years have been the most widely used receivers in precision agriculture (Figure 1, Table 1. To assess the accuracy and precision of the receivers, 9 recording stations were selected in a field (20×20 m2 and detailed mapping by the odolite camera under high precision compass networks and regular conditions (figure 2 was identified. To reduce the error of multi-path, a relatively open and unobstructed place in the Abbas Abad field of Bu-Ali Sina University were considered. This study was conducted in a Completely Randomized Design (CRD with factorial analysis to examine three factors, at three levels, each in three replication including weather conditions (clear, partially cloudy and full cloudy sky, time of day (9 am, 12 am and 4 pm and three different models of receiver (MAP 60 csx, eTrex VISTA and MAP 78s, in 9 local stations. Difference of deviation value at each station with the mean value of latitude and longitude recorded at same station was used to precision calculate on (equation 1 and the difference of deviation value at each station with a deviation of the actual position latitude and longitude of the same station was used to calculate the accuracy (equation 2. The base station position (No.1 was determined with an accurately large-scale map. Then, the positions of other stations were defined with camera and compass in exact rectangular grid by underlying base station. Mean error for each station using equation (3 and the precision and accuracy and the definitions of each receiver was calculated. Results and Discussion: To display the geographical distribution stations and the registered location data for GPS devices Arc

  16. A model-based parametric analysis of a direct ethanol polymer electrolyte membrane fuel cell performance

    Energy Technology Data Exchange (ETDEWEB)

    Andreadis, G.M.; Podias, A.K.M.; Tsiakaras, P.E. [Department of Mechanical and Industrial Engineering, School of Engineering, University of Thessaly, Pedion Areos, 383 34, Volos (Greece)


    In the present work, a model-based parametric analysis of the performance of a direct ethanol polymer electrolyte membrane fuel cell (DE-PEMFC) is conducted with the purpose to investigate the effect of several parameters on the cell's operation. The analysis is based on a previously validated one-dimensional mathematical model that describes the operation of a DE-PEMFC in steady state. More precisely, the effect of several operational and structural parameters on (i) the ethanol crossover rate from the anode to the cathode side of the cell, (ii) the parasitic current generation (mixed potential formation) and (iii) the total cell performance is investigated. According to the model predictions it was found that the increase of the ethanol feed concentration leads to higher ethanol crossover rates, higher parasitic currents and higher mixed potential values resulting in the decrease of the cell's power density. However there is an optimum ethanol feed concentration (approximately 1.0 mol L{sup -1}) for which the cell power density reaches its highest value. The platinum (Pt) loading of the anode and the cathode catalytic layers affects strongly the cell performance. Higher values of Pt loading of the catalytic layers increase the specific reaction surface area resulting in higher cell power densities. An increase of the anode catalyst loading compared to an equal one of the cathode catalyst loading has greater impact on the cell's power density. Another interesting finding is that increasing the diffusion layers' porosity up to a certain extent, improves the cell power density despite the fact that the parasitic current increases. This is explained by the fact that the reactants' concentrations over the catalysts are increased, leading to lower activation overpotential values, which are the main source of the total cell overpotentials. Moreover, the use of a thicker membrane leads to lower ethanol crossover rate, lower parasitic current and

  17. Direct comparison of elastic incoherent neutron scattering experiments with molecular dynamics simulations of DMPC phase transitions. (United States)

    Aoun, Bachir; Pellegrini, Eric; Trapp, Marcus; Natali, Francesca; Cantù, Laura; Brocca, Paola; Gerelli, Yuri; Demé, Bruno; Marek Koza, Michael; Johnson, Mark; Peters, Judith


    Neutron scattering techniques have been employed to investigate 1,2-dimyristoyl-sn -glycero-3-phosphocholine (DMPC) membranes in the form of multilamellar vesicles (MLVs) and deposited, stacked multilamellar-bilayers (MLBs), covering transitions from the gel to the liquid phase. Neutron diffraction was used to characterise the samples in terms of transition temperatures, whereas elastic incoherent neutron scattering (EINS) demonstrates that the dynamics on the sub-macromolecular length-scale and pico- to nano-second time-scale are correlated with the structural transitions through a discontinuity in the observed elastic intensities and the derived mean square displacements. Molecular dynamics simulations have been performed in parallel focussing on the length-, time- and temperature-scales of the neutron experiments. They correctly reproduce the structural features of the main gel-liquid phase transition. Particular emphasis is placed on the dynamical amplitudes derived from experiment and simulations. Two methods are used to analyse the experimental data and mean square displacements. They agree within a factor of 2 irrespective of the probed time-scale, i.e. the instrument utilized. Mean square displacements computed from simulations show a comparable level of agreement with the experimental values, albeit, the best match with the two methods varies for the two instruments. Consequently, experiments and simulations together give a consistent picture of the structural and dynamical aspects of the main lipid transition and provide a basis for future, theoretical modelling of dynamics and phase behaviour in membranes. The need for more detailed analytical models is pointed out by the remaining variation of the dynamical amplitudes derived in two different ways from experiments on the one hand and simulations on the other.

  18. Predictive modeling capabilities from incident powder and laser to mechanical properties for laser directed energy deposition (United States)

    Shin, Yung C.; Bailey, Neil; Katinas, Christopher; Tan, Wenda


    This paper presents an overview of vertically integrated comprehensive predictive modeling capabilities for directed energy deposition processes, which have been developed at Purdue University. The overall predictive models consist of vertically integrated several modules, including powder flow model, molten pool model, microstructure prediction model and residual stress model, which can be used for predicting mechanical properties of additively manufactured parts by directed energy deposition processes with blown powder as well as other additive manufacturing processes. Critical governing equations of each model and how various modules are connected are illustrated. Various illustrative results along with corresponding experimental validation results are presented to illustrate the capabilities and fidelity of the models. The good correlations with experimental results prove the integrated models can be used to design the metal additive manufacturing processes and predict the resultant microstructure and mechanical properties.

  19. Comparison study of indirect MR arthrography and direct MR arthrography of the shoulder

    Energy Technology Data Exchange (ETDEWEB)

    Jung, Jee Young; Yoon, Young Cheol [Sungkyunkwan University, Department of Radiology, Samsung Medical Center, School of Medicine, Seoul (Korea); Yi, Sang-Kyu [Sungkyunkwan University, Department of Radiology, Samsung Medical Center, School of Medicine, Seoul (Korea); Sekye Radiologic Clinic, Daejeon (Korea); Yoo, Jaechul [Sungkyunkwan University, Department of Orthopedic Surgery, School of Medicine, Seoul (Korea); Choe, Bong-Keun [Kyung Hee University, Department of Preventive Medicine, School of Medicine, Seoul (Korea)


    To compare the diagnostic value of indirect magnetic resonance arthrography (I-MRA) with that of direct MR arthrography (D-MRA) for labral tears, rotator cuff tears, and long head of biceps tendon (LHBT) tears using a 3-T MR unit. Institutional review board approval was given; written informed consent was obtained from all patients. From November 2005 to June 2006, 19 patients (eight men and 11 women; mean age, 51 years) who had undergone both I-MRA and D-MRA underwent arthroscopic surgery. Both methods were performed in fat-saturated axial, coronal oblique, and sagittal oblique T1-weighted sequences, as well as axial and coronal oblique T2-weighted sequences. Two radiologists independently and retrospectively evaluated two sets of MRA for the diagnosis of superior and anterior labral tears, subscapularis tendon (SSC), and supraspinatus-infraspinatus tendon (SSP-ISP) tears, and LHBT tears. With the arthroscopic finding as a gold standard, we analyzed statistical differences of sensitivities and specificities between two sets of MRA and inter-observer agreement was evaluated using the kappa value. The sensitivity and specificity of I-MRA and D-MRA for reader 1 were 79/80% and 71/80%, respectively, for superior labral tears; 100/100% and 100/100%, respectively, for anterior labral tears; 64/75% and 64/100%, respectively, for SSC tears; 100/86% and 100/100%, respectively, for SSP-ISP tears; and 67/100% and 78/100%, respectively, for LHBT tears. Those of I-MRA and D-MRA for reader 2 were 86/80% and 71/100%, respectively, for superior labral tears; 100/83% and 100/100%, respectively, for anterior labral tears; 64/88% and 82/100%, respectively, for SSC tears; 92/86% and 100/100%, respectively, for SSP-ISP tears; and 78/90% and 89/100%, respectively, for LHBT tears. No significant differences were found between the methods. Inter-observer agreements were higher than moderate ({kappa} > 0.41) with both methods. Based on a relatively small number of patients, no significant

  20. Verification of extended model of goal directed behavior applied on aggression

    Directory of Open Access Journals (Sweden)

    Katarína Vasková


    Full Text Available The study was aimed to verify Model of Goal Directed Behavior (EMGB by Perugini and Bagozzi (2001 applied on aggression by Richetin, Richardson and Boykin (2011. Two different studies were performed. Firstly original form of model was verified. In the second study, modification of EMGB through new conceptualization of scale of perceived behavioral control was executed. The research sample consisted together from 385 students of University of P.J. Šafárik and High school in Košice (182 respondents (78 men, 104 women with average age 20,84 years and standard deviation 1,94, who were involved in first study and 203 students (49 men and 154 women, with average age 19,71 and standard deviation 1,99 participated in second study who were administrated questionnaire by Richetin et al. (2011 and Richardson Conflict Response Questionnaire (Richardson & Green, 2006. Expectancy of comparable relationships between particular factors of EMGB in comparison to its published original version was verified. Data were analyzed by structural equation modeling. In first study was shown insufficient fit of EMGB model. There were hypothesized two main sources of problems. At first, weak relationship between attitudes and behavioral desire was shown. Following statistical procedures confirmed its direct impact on intention, what is in correspondence with another studies (see Leone, Perugini & Ercolani, 2004, Perugini & Bagozzi, 2001, Richetin et al., 2011. Second source of problems was identified in factor named perceived behavioral control. Difficulties from our point of view lied in conceptualization of the term and its subsequent measurement. In the second study was involved new conceptualization of control. It corresponded with Baumeister´s understanding of selfcontrol as asserting control over one´s emotions, thoughts and behavior. After this modification sufficient fit of EMGB was shown. Besides this, factor of self-control was the strongest predictor of

  1. Direct comparison of eight national FRAX® tools for fracture prediction and treatment qualification in Canadian women. (United States)

    Leslie, W D; Brennan, S L; Lix, L M; Johansson, H; Oden, A; McCloskey, E; Kanis, J A


    We compared the calibration of FRAX tools from Canada, the US (white), UK, Sweden, France, Australia, New Zealand, and China when used to assess fracture risk in 36,730 Canadian women. Our data underscores the importance of applying country-specific FRAX tools that are based upon high-quality national fracture epidemiology. A FRAX® model for Canada was constructed for prediction of hip fracture and major osteoporotic fracture (MOF) using national hip fracture and mortality data. We examined the calibration of this model in Canadian women and compared it with seven other FRAX tools. In women aged ≥50 years with baseline bone mineral density (BMD) measures identified from the Manitoba Bone Density Program, Canada (n = 36,730), 10-year fracture probabilities were calculated with and without BMD using selected country-specific FRAX tools. FRAX risk estimates were compared with observed fractures ≤10 years (506 hip, 2,380 MOF). Ten-year fracture risk was compared with predicted probabilities, and proportions exceeding specific treatment thresholds contrasted. For hip fracture prediction, good calibration was observed for FRAX Canada and most other country-specific FRAX tools, excepting Sweden (risk overestimated) and China (risk underestimated). For MOF prediction, greater between-country differences were seen; FRAX Sweden and FRAX China showed the largest over- and underestimation in this Canadian population. Relative to treatment qualification based upon FRAX Canada, treatment of high-hip fracture probability (≥3%) was greater by FRAX Sweden (ratio 1.41 without and 1.55 with BMD), and markedly less by FRAX China (ratio 0.09 without and 0.11 with BMD). Greater between-country differences were observed for treatment of high MOF (≥20%); FRAX Sweden again greatly increased (ratio 1.76 without and 1.83 with BMD), and FRAX China severely reduced treatment qualification (ratio 0.00 without and 0.01 with BMD). The use of country-specific FRAX tools, accurately

  2. An Experimental Comparison of Similarity Assessment Measures for 3D Models on Constrained Surface Deformation (United States)

    Quan, Lulin; Yang, Zhixin


    To address the issues in the area of design customization, this paper expressed the specification and application of the constrained surface deformation, and reported the experimental performance comparison of three prevail effective similarity assessment algorithms on constrained surface deformation domain. Constrained surface deformation becomes a promising method that supports for various downstream applications of customized design. Similarity assessment is regarded as the key technology for inspecting the success of new design via measuring the difference level between the deformed new design and the initial sample model, and indicating whether the difference level is within the limitation. According to our theoretical analysis and pre-experiments, three similarity assessment algorithms are suitable for this domain, including shape histogram based method, skeleton based method, and U system moment based method. We analyze their basic functions and implementation methodologies in detail, and do a series of experiments on various situations to test their accuracy and efficiency using precision-recall diagram. Shoe model is chosen as an industrial example for the experiments. It shows that shape histogram based method gained an optimal performance in comparison. Based on the result, we proposed a novel approach that integrating surface constrains and shape histogram description with adaptive weighting method, which emphasize the role of constrains during the assessment. The limited initial experimental result demonstrated that our algorithm outperforms other three algorithms. A clear direction for future development is also drawn at the end of the paper.

  3. Mathematical interpretation of Brownian motor model: Limit cycles and directed transport phenomena (United States)

    Yang, Jianqiang; Ma, Hong; Zhong, Suchuang


    In this article, we first suggest that the attractor of Brownian motor model is one of the reasons for the directed transport phenomenon of Brownian particle. We take the classical Smoluchowski-Feynman (SF) ratchet model as an example to investigate the relationship between limit cycles and directed transport phenomenon of the Brownian particle. We study the existence and variation rule of limit cycles of SF ratchet model at changing parameters through mathematical methods. The influences of these parameters on the directed transport phenomenon of a Brownian particle are then analyzed through numerical simulations. Reasonable mathematical explanations for the directed transport phenomenon of Brownian particle in SF ratchet model are also formulated on the basis of the existence and variation rule of the limit cycles and numerical simulations. These mathematical explanations provide a theoretical basis for applying these theories in physics, biology, chemistry, and engineering.

  4. Environmental Anchoring of Head Direction in a Computational Model of Retrosplenial Cortex. (United States)

    Bicanski, Andrej; Burgess, Neil


    Allocentric (world-centered) spatial codes driven by path integration accumulate error unless reset by environmental sensory inputs that are necessarily egocentric (body-centered). Previous models of the head direction system avoided the necessary transformation between egocentric and allocentric reference frames by placing visual cues at infinity. Here we present a model of head direction coding that copes with exclusively proximal cues by making use of a conjunctive representation of head direction and location in retrosplenial cortex. Egocentric landmark bearing of proximal cues, which changes with location, is mapped onto this retrosplenial representation. The model avoids distortions due to parallax, which occur in simple models when a single proximal cue card is used, and can also accommodate multiple cues, suggesting how it can generalize to arbitrary sensory environments. It provides a functional account of the anatomical distribution of head direction cells along Papez' circuit, of place-by-direction coding in retrosplenial cortex, the anatomical connection from the anterior thalamic nuclei to retrosplenial cortex, and the involvement of retrosplenial cortex in navigation. In addition to parallax correction, the same mechanism allows for continuity of head direction coding between connected environments, and shows how a head direction representation can be stabilized by a single within arena cue. We also make predictions for drift during exploration of a new environment, the effects of hippocampal lesions on retrosplenial cells, and on head direction coding in differently shaped environments. The activity of head direction cells signals the direction of an animal's head relative to landmarks in the world. Although driven by internal estimates of head movements, head direction cells must be kept aligned to the external world by sensory inputs, which arrive in the reference frame of the sensory receptors. We present a computational model, which proposes that

  5. Metal Mixture Modeling Evaluation project: 2. Comparison of four modeling approaches (United States)

    Farley, Kevin J.; Meyer, Joe; Balistrieri, Laurie S.; DeSchamphelaere, Karl; Iwasaki, Yuichi; Janssen, Colin; Kamo, Masashi; Lofts, Steve; Mebane, Christopher A.; Naito, Wataru; Ryan, Adam C.; Santore, Robert C.; Tipping, Edward


    As part of the Metal Mixture Modeling Evaluation (MMME) project, models were developed by the National Institute of Advanced Industrial Science and Technology (Japan), the U.S. Geological Survey (USA), HDR⎪HydroQual, Inc. (USA), and the Centre for Ecology and Hydrology (UK) to address the effects of metal mixtures on biological responses of aquatic organisms. A comparison of the 4 models, as they were presented at the MMME Workshop in Brussels, Belgium (May 2012), is provided herein. Overall, the models were found to be similar in structure (free ion activities computed by WHAM; specific or non-specific binding of metals/cations in or on the organism; specification of metal potency factors and/or toxicity response functions to relate metal accumulation to biological response). Major differences in modeling approaches are attributed to various modeling assumptions (e.g., single versus multiple types of binding site on the organism) and specific calibration strategies that affected the selection of model parameters. The models provided a reasonable description of additive (or nearly additive) toxicity for a number of individual toxicity test results. Less-than-additive toxicity was more difficult to describe with the available models. Because of limitations in the available datasets and the strong inter-relationships among the model parameters (log KM values, potency factors, toxicity response parameters), further evaluation of specific model assumptions and calibration strategies is needed.

  6. Bivariate Gaussian bridges: directional factorization of diffusion in Brownian bridge models. (United States)

    Kranstauber, Bart; Safi, Kamran; Bartumeus, Frederic


    In recent years high resolution animal tracking data has become the standard in movement ecology. The Brownian Bridge Movement Model (BBMM) is a widely adopted approach to describe animal space use from such high resolution tracks. One of the underlying assumptions of the BBMM is isotropic diffusive motion between consecutive locations, i.e. invariant with respect to the direction. Here we propose to relax this often unrealistic assumption by separating the Brownian motion variance into two directional components, one parallel and one orthogonal to the direction of the motion. Our new model, the Bivariate Gaussian bridge (BGB), tracks movement heterogeneity across time. Using the BGB and identifying directed and non-directed movement within a trajectory resulted in more accurate utilisation distributions compared to dynamic Brownian bridges, especially for trajectories with a non-isotropic diffusion, such as directed movement or Lévy like movements. We evaluated our model with simulated trajectories and observed tracks, demonstrating that the improvement of our model scales with the directional correlation of a correlated random walk. We find that many of the animal trajectories do not adhere to the assumptions of the BBMM. The proposed model improves accuracy when describing the space use both in simulated correlated random walks as well as observed animal tracks. Our novel approach is implemented and available within the "move" package for R.

  7. Tools for model-independent bounds in direct dark matter searches

    DEFF Research Database (Denmark)

    Cirelli, M.; Del Nobile, E.; Panci, P.


    We discuss a framework (based on non-relativistic operators) and a self-contained set of numerical tools to derive the bounds from some current direct detection experiments on virtually any arbitrary model of Dark Matter elastically scattering on nuclei.......We discuss a framework (based on non-relativistic operators) and a self-contained set of numerical tools to derive the bounds from some current direct detection experiments on virtually any arbitrary model of Dark Matter elastically scattering on nuclei....

  8. Climatic Calibration of Paleoecological Data and Data/Model Comparisons (United States)

    Webb, T.; Bartlein, P. J.; Shuman, B.; Williams, J. W.


    When accurately and precisely dated, paleoecological data along with geochemical data and geomorphological features indicate past changes in climate. Calibrating these data in terms of standard climatic (e.g. July mean temperature) or bioclimatic (e.g. winter extreme temperatures) variables has allowed construction of paleoclimatic maps and time series that not only show the magnitude and extent of the difference in past climates but also can be compared to the output from global climate and earth-system models. Key to judging the reliability of the derived paleoclimatic estimates is the qualitative and quantitative comparison of estimates from different paleoclimatic indicators to show whether consistent or discrepant patterns exist. Here "multi-proxy" studies of independent paleoclimatic indicators from single cores, single basins, and multiple sites are providing many new opportunities to test calibration methods and results. The multi-proxy studies are also allowing researchers to develop a multivariate view of climate because different types of data, whether paleoecological or geochemical, often are sensitive to different aspects of climate change. These can be temperature changes and/or moisture changes as well as changes in seasonality or climatic extremes. Recent research mapping late Quaternary pollen, geochemical, and lake-level data across eastern North America in 1000-yr intervals illustrates some the advances gained from this multi-proxy approach to the reconstruction of past climates since the last glacial maximum 21,000 years ago.

  9. Methane airborne measurements and comparison to global models during BARCA (United States)

    Beck, Veronika; Chen, Huilin; Gerbig, Christoph; Bergamaschi, Peter; Bruhwiler, Lori; Houweling, Sander; Röckmann, Thomas; Kolle, Olaf; Steinbach, Julia; Koch, Thomas; Sapart, Célia J.; van der Veen, Carina; Frankenberg, Christian; Andreae, Meinrat O.; Artaxo, Paulo; Longo, Karla M.; Wofsy, Steven C.


    Tropical regions, especially the Amazon region, account for large emissions of methane (CH4). Here, we present CH4 observations from two airborne campaigns conducted within the BARCA (Balanço Atmosférico Regional de Carbono na Amazônia) project in the Amazon basin in November 2008 (end of the dry season) and May 2009 (end of the wet season). We performed continuous measurements of CH4 onboard an aircraft for the first time in the Amazon region, covering the whole Amazon basin with over 150 vertical profiles between altitudes of 500 m and 4000 m. The observations support the finding of previous ground-based, airborne, and satellite measurements that the Amazon basin is a large source of atmospheric CH4. Isotope analysis verified that the majority of emissions can be attributed to CH4 emissions from wetlands, while urban CH4 emissions could be also traced back to biogenic origin. A comparison of five TM5 based global CH4 inversions with the observations clearly indicates that the inversions using SCIAMACHY observations represent the BARCA observations best. The calculated CH4 flux estimate obtained from the mismatch between observations and TM5-modeled CH4 fields ranges from 36 to 43 mg m-2 d-1 for the Amazon lowland region.

  10. Interlaboratory model comparisons of atmospheric concentrations with and without deposition

    International Nuclear Information System (INIS)

    Kern, C.D.; Cooper, R.E.


    To calculate the dose to the regional and U.S. populations, the pollutant concentration both with and without deposition and the amount of material deposited on the ground and watersheds around such a facility must be known. The following report (Article 50) of this document contains some initial estimates of population exposure from atmospheric effluents. The expertise of laboratories supported by U.S. Department of Energy funds ensures that the latest methods and data are available. Lawrence Livermore Laboratory (LLL) performed regional calculations (out to distances of the order of 200 km from a hypothetical fuel reprocessing plant). The Air Resources Laboratory (ARL) of the National Oceanic and Atmospheric Administration (NOAA), and Battelle Pacific Northwest Laboratories (PNL) performed U.S. scale calculations, and ARL also did the global calculations. Data from a winter and summer period were used to make comparisons of calculations by LLL, ARL, and PNL to determine which model should be used for the final calculations and to determine if a 200-km square area centered on the site would be large enough for dose calculations via the water and food pathways

  11. Recent and Past Musical Activity Predicts Cognitive Aging Variability: Direct Comparison with Leisure Activities

    Directory of Open Access Journals (Sweden)

    Brenda eHanna-Pladdy


    Full Text Available Studies evaluating the impact of modifiable lifestyle factors on cognition offer potential insights into sources of cognitive aging variability. Recently, we reported an association between extent of musical instrumental practice throughout the life span (greater than 10 years on preserved cognitive functioning in advanced age . These findings raise the question of whether there are training-induced brain changes in musicians that can transfer to nonmusical cognitive abilities to allow for compensation of age-related cognitive declines. However, because of the relationship between engagement in lifestyle activities and preserved cognition, it remains unclear whether these findings are specifically driven by musical training or the types of individuals likely to engage in greater activities in general. The current study examined the type of leisure activity (musical versus other as well as the timing of engagement (age of acquisition, past versus recent in predictive models of successful cognitive aging. Seventy age and education matched older musicians (> 10 years and nonmusicians (ages 59-80 were evaluated on neuropsychological tests and life-style activities (AAP. Partition analyses were conducted on significant cognitive measures to explain performance variance in musicians. Musicians scored higher on tests of phonemic fluency, verbal immediate recall, judgment of line orientation (JLO, and Letter Number Sequencing (LNS, but not the AAP. The first partition analysis revealed education best predicted JLO in musicians, followed by recent musical engagement which offset low education. In the second partition analysis, early age of musical acquisition (< 9 years predicted enhanced LNS in musicians, while analyses for AAP, verbal recall and fluency were not predictive. Recent and past musical activity, but not leisure activity, predicted variability across verbal and visuospatial domains in aging. Early musical acquisition predicted auditory

  12. Recent and past musical activity predicts cognitive aging variability: direct comparison with general lifestyle activities. (United States)

    Hanna-Pladdy, Brenda; Gajewski, Byron


    Studies evaluating the impact of modifiable lifestyle factors on cognition offer potential insights into sources of cognitive aging variability. Recently, we reported an association between extent of musical instrumental practice throughout the life span (greater than 10 years) on preserved cognitive functioning in advanced age. These findings raise the question of whether there are training-induced brain changes in musicians that can transfer to non-musical cognitive abilities to allow for compensation of age-related cognitive declines. However, because of the relationship between engagement in general lifestyle activities and preserved cognition, it remains unclear whether these findings are specifically driven by musical training or the types of individuals likely to engage in greater activities in general. The current study controlled for general activity level in evaluating cognition between musicians and nomusicians. Also, the timing of engagement (age of acquisition, past versus recent) was assessed in predictive models of successful cognitive aging. Seventy age and education matched older musicians (>10 years) and non-musicians (ages 59-80) were evaluated on neuropsychological tests and general lifestyle activities. Musicians scored higher on tests of phonemic fluency, verbal working memory, verbal immediate recall, visuospatial judgment, and motor dexterity, but did not differ in other general leisure activities. Partition analyses were conducted on significant cognitive measures to determine aspects of musical training predictive of enhanced cognition. The first partition analysis revealed education best predicted visuospatial functions in musicians, followed by recent musical engagement which offset low education. In the second partition analysis, early age of musical acquisition (memory in musicians, while analyses for other measures were not predictive. Recent and past musical activity, but not general lifestyle activities, predicted variability

  13. Heteroscedasticity as a Basis of Direction Dependence in Reversible Linear Regression Models. (United States)

    Wiedermann, Wolfgang; Artner, Richard; von Eye, Alexander


    Heteroscedasticity is a well-known issue in linear regression modeling. When heteroscedasticity is observed, researchers are advised to remedy possible model misspecification of the explanatory part of the model (e.g., considering alternative functional forms and/or omitted variables). The present contribution discusses another source of heteroscedasticity in observational data: Directional model misspecifications in the case of nonnormal variables. Directional misspecification refers to situations where alternative models are equally likely to explain the data-generating process (e.g., x → y versus y → x). It is shown that the homoscedasticity assumption is likely to be violated in models that erroneously treat true nonnormal predictors as response variables. Recently, Direction Dependence Analysis (DDA) has been proposed as a framework to empirically evaluate the direction of effects in linear models. The present study links the phenomenon of heteroscedasticity with DDA and describes visual diagnostics and nine homoscedasticity tests that can be used to make decisions concerning the direction of effects in linear models. Results of a Monte Carlo simulation that demonstrate the adequacy of the approach are presented. An empirical example is provided, and applicability of the methodology in cases of violated assumptions is discussed.

  14. A fractal comparison of real and Austrian business cycle models (United States)

    Mulligan, Robert F.


    Rescaled range and power spectral density analysis are applied to examine a diverse set of macromonetary data for fractal character and stochastic dependence. Fractal statistics are used to evaluate two competing models of the business cycle, Austrian business cycle theory and real business cycle theory. Strong evidence is found for antipersistent stochastic dependence in transactions money (M1) and components of the monetary aggregates most directly concerned with transactions, which suggests an activist monetary policy. Savings assets exhibit persistent long memory, as do those monetary aggregates which include savings assets, such as savings money (M2), M2 minus small time deposits, and money of zero maturity (MZM). Virtually all measures of economic activity display antipersistence, and this finding is invariant to whether the measures are adjusted for inflation, including real gross domestic product, real consumption expenditures, real fixed private investment, and labor productivity. This strongly disconfirms real business cycle theory.

  15. Comparison of methods for modelling geomagnetically induced currents (United States)

    Boteler, D. H.; Pirjola, R. J.


    Assessing the geomagnetic hazard to power systems requires reliable modelling of the geomagnetically induced currents (GIC) produced in the power network. This paper compares the Nodal Admittance Matrix method with the Lehtinen-Pirjola method and shows them to be mathematically equivalent. GIC calculation using the Nodal Admittance Matrix method involves three steps: (1) using the voltage sources in the lines representing the induced geoelectric field to calculate equivalent current sources and summing these to obtain the nodal current sources, (2) performing the inversion of the admittance matrix and multiplying by the nodal current sources to obtain the nodal voltages, (3) using the nodal voltages to determine the currents in the lines and in the ground connections. In the Lehtinen-Pirjola method, steps 2 and 3 of the Nodal Admittance Matrix calculation are combined into one matrix expression. This involves inversion of a more complicated matrix but yields the currents to ground directly from the nodal current sources. To calculate GIC in multiple voltage levels of a power system, it is necessary to model the connections between voltage levels, not just the transmission lines and ground connections considered in traditional GIC modelling. Where GIC flow to ground through both the high-voltage and low-voltage windings of a transformer, they share a common path through the substation grounding resistance. This has been modelled previously by including non-zero, off-diagonal elements in the earthing impedance matrix of the Lehtinen-Pirjola method. However, this situation is more easily handled in both the Nodal Admittance Matrix method and the Lehtinen-Pirjola method by introducing a node at the neutral point.

  16. Comparison of methods for modelling geomagnetically induced currents

    Directory of Open Access Journals (Sweden)

    D. H. Boteler


    Full Text Available Assessing the geomagnetic hazard to power systems requires reliable modelling of the geomagnetically induced currents (GIC produced in the power network. This paper compares the Nodal Admittance Matrix method with the Lehtinen–Pirjola method and shows them to be mathematically equivalent. GIC calculation using the Nodal Admittance Matrix method involves three steps: (1 using the voltage sources in the lines representing the induced geoelectric field to calculate equivalent current sources and summing these to obtain the nodal current sources, (2 performing the inversion of the admittance matrix and multiplying by the nodal current sources to obtain the nodal voltages, (3 using the nodal voltages to determine the currents in the lines and in the ground connections. In the Lehtinen–Pirjola method, steps 2 and 3 of the Nodal Admittance Matrix calculation are combined into one matrix expression. This involves inversion of a more complicated matrix but yields the currents to ground directly from the nodal current sources. To calculate GIC in multiple voltage levels of a power system, it is necessary to model the connections between voltage levels, not just the transmission lines and ground connections considered in traditional GIC modelling. Where GIC flow to ground through both the high-voltage and low-voltage windings of a transformer, they share a common path through the substation grounding resistance. This has been modelled previously by including non-zero, off-diagonal elements in the earthing impedance matrix of the Lehtinen–Pirjola method. However, this situation is more easily handled in both the Nodal Admittance Matrix method and the Lehtinen–Pirjola method by introducing a node at the neutral point.

  17. Prediction and Validation of Heat Release Direct Injection Diesel Engine Using Multi-Zone Model (United States)

    Anang Nugroho, Bagus; Sugiarto, Bambang; Prawoto; Shalahuddin, Lukman


    The objective of this study is to develop simulation model which capable to predict heat release of diesel combustion accurately in efficient computation time. A multi-zone packet model has been applied to solve the combustion phenomena inside diesel cylinder. The model formulations are presented first and then the numerical results are validated on a single cylinder direct injection diesel engine at various engine speed and timing injections. The model were found to be promising to fulfill the objective above.

  18. Direct Detection Phenomenology in Models Where the Products of Dark Matter Annihilation Interact with Nuclei

    DEFF Research Database (Denmark)

    Cherry, John F.; Frandsen, Mads T.; Shoemaker, Ian M.


    We investigate the direct detection phenomenology of a class of dark matter (DM) models in which DM does not directly interact with nuclei, {but rather} the products of its annihilation do. When these annihilation products are very light compared to the DM mass, the scattering in direct detection...... to nuclei, the limit from annihilation to relativistic particles in the Sun can be stronger than that of conventional non-relativistic direct detection by more than three orders of magnitude for masses in a 2-7 GeV window....

  19. Comparison of Chemicon SimulFluor direct fluorescent antibody staining with cell culture and shell vial direct immunoperoxidase staining for detection of herpes simplex virus and with cytospin direct immunofluorescence staining for detection of varicella-zoster virus. (United States)

    Chan, E L; Brandt, K; Horsman, G B


    A new rapid direct immunofluorescence assay, the SimulFluor direct fluorescent-antibody (DFA) assay, which can simultaneously detect herpes simplex virus types 1 and 2 (HSV-1 and -2) and varicella-zoster virus (VZV), was evaluated in comparison with our current standard procedures of (i) shell vial direct immunoperoxidase (shell vial IP) staining and cell culture for detection of HSV and (ii) cytospin DFA staining for VZV detection. A total of 517 vesicular, oral, genital, and skin lesion specimens were tested by all three procedures. For HSV detection, the SimulFluor DFA assay had an overall sensitivity, specificity, positive predictive value, and negative predictive value of 80.0, 98.3, 92.3, and 95.1%, respectively, when compared to culture. Shell vial IP staining had a sensitivity, specificity, positive predictive value, and negative predictive value of 87.6, 100, 100, and 96.9%, respectively, when compared with cell culture. The SimulFluor DFA assay, however, offers same-day, 1.5-hours results versus a 1- to 2-day wait for shell vial IP staining results and a 1- to 6-day wait for culture results for HSV. For VZV detection SimulFluor DFA staining detected 27 positive specimens as compared to 31 by our standard cytospin DFA technique--a correlation of 87.1%. A positive SimulFluor reaction for VZV is indicated by yellow-gold fluorescence compared to the bright apple-green fluorescence observed by cytospin DFA staining. There is no difference in turnaround time between the two assays. The SimulFluor DFA assay is a rapid immunofluorescence assay that can detect 80% of the HSV-positive specimens and 87% of the VZV-positive specimens with a 1.5-h turnaround time.

  20. Comparison of static model and dynamic model for the evaluation of station blackout sequences

    International Nuclear Information System (INIS)

    Lee, Kwang-Nam; Kang, Sun-Koo; Hong, Sung-Yull.


    Station blackout is one of major contributors to the core damage frequency (CDF) in many PSA studies. Since station blackout sequence exhibits dynamic features, accurate calculation of CDF for the station blackout sequence is not possible with event tree/fault tree (ET/FT) method. Although the integral method can determine accurate CDF, it is time consuming and is difficult to evaluate various alternative AC source configuration and sensitivities. In this study, a comparison is made between static model and dynamic model and a new methodology which combines static model and dynamic model is provided for the accurate quantification of CDF and evaluation of improvement alternatives. Results of several case studies show that accurate calculation of CDF is possible by introducing equivalent mission time. (author)

  1. The rise of digital direct-to-consumer advertising?: Comparison of direct-to-consumer advertising expenditure trends from publicly available data sources and global policy implications. (United States)

    Mackey, Tim K; Cuomo, Raphael E; Liang, Bryan A


    Pharmaceutical marketing is undergoing a major shift in the United States, in part due to new transparency regulations under the healthcare reform act. Changes in pharmaceutical marketing practices include a possible shift from more traditional forms of direct-to-consumer advertising towards emerging use of Internet-based DTCA ("eDTCA") given the growing importance of digital health or "eHealth." Though legally allowed only in the U.S. and New Zealand, eDTCA poses novel regulatory challenges, as it can cross geopolitical boundaries and impact health systems and populations outside of these countries. We wished to assess whether changes in DTCA and eDTCA expenditure trends was occurring using publicly available pharmaceutical marketing data. DTCA data was analyzed to compare trends in aggregate marketing expenditures and to assess if there were statistically significant differences in trends and magnitudes for data sources and DTCA sub-categories (including eDTCA). This was accomplished using regression lines of DTCA trend data and conducting pairwise comparisons of regression coefficients using t-tests. Means testing was utilized for comparing magnitude of DTCA expenditure. Data from multiple data sources indicate that aggregate DTCA expenditures have slightly declined during the period from 2005-2009 and are consistent with results from other studies. For DTCA sub-categories, television remained the most utilized form of DTCA, though experienced trends of declining expenditures (-13.2 %) similar to other traditional media platforms such as radio (-30.7 %) and outdoor ads (-12.1 %). The only DTCA sub-category that experienced substantial increased expenditures was eDTCA (+109.0 %) and it was the only medium that had statistically significant differences in its marketing expenditure trends compared to other DTCA sub-categories. Our study indicates that traditional DTCA marketing may be on the decline. Conversely, the only DTCA sub-category that experienced

  2. The Bolund Experiment. Part II: Blind Comparison of Microscale Flow Models

    DEFF Research Database (Denmark)

    Bechmann, Andreas; Sørensen, Niels N.; Berg, Jacob


    Bolund measurements were used for a blind comparison of microscale flow models. Fifty-seven models ranging from numerical to physical were used, including large-eddy simulation (LES) models, Reynolds-averaged Navier–Stokes (RANS) models, and linearized models, in addition to wind-tunnel and water...

  3. The Sim-SEQ Project: Comparison of Selected Flow Models for the S-3 Site

    Energy Technology Data Exchange (ETDEWEB)

    Mukhopadhyay, Sumit; Doughty, Christine A.; Bacon, Diana H.; Li, Jun; Wei, Lingli; Yamamoto, Hajime; Gasda, Sarah E.; Hosseini, Seyyed; Nicot, Jean-Philippe; Birkholzer, Jens


    Sim-SEQ is an international initiative on model comparison for geologic carbon sequestration, with an objective to understand and, if possible, quantify model uncertainties. Model comparison efforts in Sim-SEQ are at present focusing on one specific field test site, hereafter referred to as the Sim-SEQ Study site (or S-3 site). Within Sim-SEQ, different modeling teams are developing conceptual models of CO2 injection at the S-3 site. In this paper, we select five flow models of the S-3 site and provide a qualitative comparison of their attributes and predictions. These models are based on five different simulators or modeling approaches: TOUGH2/EOS7C, STOMP-CO2e, MoReS, TOUGH2-MP/ECO2N, and VESA. In addition to model-to-model comparison, we perform a limited model-to-data comparison, and illustrate how model choices impact model predictions. We conclude the paper by making recommendations for model refinement that are likely to result in less uncertainty in model predictions.

  4. An empirically grounded agent based model for modeling directs, conflict detection and resolution operations in air traffic management. (United States)

    Bongiorno, Christian; Miccichè, Salvatore; Mantegna, Rosario N


    We present an agent based model of the Air Traffic Management socio-technical complex system aiming at modeling the interactions between aircraft and air traffic controllers at a tactical level. The core of the model is given by the conflict detection and resolution module and by the directs module. Directs are flight shortcuts that are given by air controllers to speed up the passage of an aircraft within a certain airspace and therefore to facilitate airline operations. Conflicts between flight trajectories can occur for two main reasons: either the planning of the flight trajectory was not sufficiently detailed to rule out all potential conflicts or unforeseen events during the flight require modifications of the flight plan that can conflict with other flight trajectories. Our model performs a local conflict detection and resolution procedure. Once a flight trajectory has been made conflict-free, the model searches for possible improvements of the system efficiency by issuing directs. We give an example of model calibration based on real data. We then provide an illustration of the capability of our model in generating scenario simulations able to give insights about the air traffic management system. We show that the calibrated model is able to reproduce the existence of a geographical localization of air traffic controllers' operations. Finally, we use the model to investigate the relationship between directs and conflict resolutions (i) in the presence of perfect forecast ability of controllers, and (ii) in the presence of some degree of uncertainty in flight trajectory forecast.

  5. An empirically grounded agent based model for modeling directs, conflict detection and resolution operations in air traffic management.

    Directory of Open Access Journals (Sweden)

    Christian Bongiorno

    Full Text Available We present an agent based model of the Air Traffic Management socio-technical complex system aiming at modeling the interactions between aircraft and air traffic controllers at a tactical level. The core of the model is given by the conflict detection and resolution module and by the directs module. Directs are flight shortcuts that are given by air controllers to speed up the passage of an aircraft within a certain airspace and therefore to facilitate airline operations. Conflicts between flight trajectories can occur for two main reasons: either the planning of the flight trajectory was not sufficiently detailed to rule out all potential conflicts or unforeseen events during the flight require modifications of the flight plan that can conflict with other flight trajectories. Our model performs a local conflict detection and resolution procedure. Once a flight trajectory has been made conflict-free, the model searches for possible improvements of the system efficiency by issuing directs. We give an example of model calibration based on real data. We then provide an illustration of the capability of our model in generating scenario simulations able to give insights about the air traffic management system. We show that the calibrated model is able to reproduce the existence of a geographical localization of air traffic controllers' operations. Finally, we use the model to investigate the relationship between directs and conflict resolutions (i in the presence of perfect forecast ability of controllers, and (ii in the presence of some degree of uncertainty in flight trajectory forecast.

  6. Direct comparison of in vivo versus postmortem second-order motion-compensated cardiac diffusion tensor imaging. (United States)

    Stoeck, Christian T; von Deuster, Constantin; Fleischmann, Thea; Lipiski, Miriam; Cesarovic, Nikola; Kozerke, Sebastian


    To directly compare in vivo versus postmortem second-order motion-compensated spin-echo diffusion tensor imaging of the porcine heart. Second-order motion-compensated spin-echo cardiac diffusion tensor imaging was performed during systolic contraction in vivo and repeated upon cardiac arrest by bariumchloride without repositioning of the study animal or replaning of imaging slices. In vivo and postmortem reproducibility was assessed by repeat measurements. Comparison of helix, transverse, and sheet (E2A) angulation as well as mean diffusivity and fractional anisotropy was performed. Intraclass correlation coefficients for repeated measurements (postmortem/in vivo) were 0.95/0.96 for helix, 0.70/0.66 for transverse, and 0.79/0.72 for E2A angulation; 0.83/0.72 for mean diffusivity; and 0.78/0.76 for fractional anisotropy. The corresponding 95% levels of agreement across the left ventricle were: helix 14 to 18°/12 to 15°, transverse 9 to 10°/10 to 11°, E2A 15 to 20°/16 to 18°. The 95% levels of agreement across the left ventricle for the comparison of postmortem versus in vivo were 20 to 22° for helix, 13 to 19° for transverse, and 24 to 31° for E2A angulation. Parameters derived from in vivo second-order motion-compensated spin-echo diffusion tensor imaging agreed well with postmortem imaging, indicating sufficient suppression of motion-induced signal distortions of in vivo cardiac diffusion tensor imaging. Magn Reson Med 79:2265-2276, 2018. © 2017 International Society for Magnetic Resonance in Medicine. © 2017 International Society for Magnetic Resonance in Medicine.

  7. Quantification of the Relative Biological Effectiveness for Ion Beam Radiotherapy: Direct Experimental Comparison of Proton and Carbon Ion Beams and a Novel Approach for Treatment Planning

    International Nuclear Information System (INIS)

    Elsaesser, Thilo; Weyrather, Wilma K.; Friedrich, Thomas; Durante, Marco; Iancu, Gheorghe; Kraemer, Michael; Kragl, Gabriele; Brons, Stephan; Winter, Marcus; Weber, Klaus-Josef; Scholz, Michael


    Purpose: To present the first direct experimental in vitro comparison of the biological effectiveness of range-equivalent protons and carbon ion beams for Chinese hamster ovary cells exposed in a three-dimensional phantom using a pencil beam scanning technique and to compare the experimental data with a novel biophysical model. Methods and Materials: Cell survival was measured in the phantom after irradiation with two opposing fields, thus mimicking the typical patient treatment scenario. The novel biophysical model represents a substantial extension of the local effect model, previously used for treatment planning in carbon ion therapy for more than 400 patients, and potentially can be used to predict effectiveness of all ion species relevant for radiotherapy. A key feature of the new approach is the more sophisticated consideration of spatially correlated damage induced by ion irradiation. Results: The experimental data obtained for Chinese hamster ovary cells clearly demonstrate that higher cell killing is achieved in the target region with carbon ions as compared with protons when the effects in the entrance channel are comparable. The model predictions demonstrate agreement with these experimental data and with data obtained with helium ions under similar conditions. Good agreement is also achieved with relative biological effectiveness values reported in the literature for other cell lines for monoenergetic proton, helium, and carbon ions. Conclusion: Both the experimental data and the new modeling approach are supportive of the advantages of carbon ions as compared with protons for treatment-like field configurations. Because the model predicts the effectiveness for several ion species with similar accuracy, it represents a powerful tool for further optimization and utilization of the potential of ion beams in tumor therapy.

  8. Direct comparison of flow-FISH and qPCR as diagnostic tests for telomere length measurement in humans.

    Directory of Open Access Journals (Sweden)

    Fernanda Gutierrez-Rodrigues

    Full Text Available Telomere length measurement is an essential test for the diagnosis of telomeropathies, which are caused by excessive telomere erosion. Commonly used methods are terminal restriction fragment (TRF analysis by Southern blot, fluorescence in situ hybridization coupled with flow cytometry (flow-FISH, and quantitative PCR (qPCR. Although these methods have been used in the clinic, they have not been comprehensively compared. Here, we directly compared the performance of flow-FISH and qPCR to measure leukocytes' telomere length of healthy individuals and patients evaluated for telomeropathies, using TRF as standard. TRF and flow-FISH showed good agreement and correlation in the analysis of healthy subjects (R(2 = 0.60; p<0.0001 and patients (R(2 = 0.51; p<0.0001. In contrast, the comparison between TRF and qPCR yielded modest correlation for the analysis of samples of healthy individuals (R(2 = 0.35; p<0.0001 and low correlation for patients (R(2 = 0.20; p = 0.001; Bland-Altman analysis showed poor agreement between the two methods for both patients and controls. Quantitative PCR and flow-FISH modestly correlated in the analysis of healthy individuals (R(2 = 0.33; p<0.0001 and did not correlate in the comparison of patients' samples (R(2 = 0.1, p = 0.08. Intra-assay coefficient of variation (CV was similar for flow-FISH (10.8 ± 7.1% and qPCR (9.5 ± 7.4%; p = 0.35, but the inter-assay CV was lower for flow-FISH (9.6 ± 7.6% vs. 16 ± 19.5%; p = 0.02. Bland-Altman analysis indicated that flow-FISH was more precise and reproducible than qPCR. Flow-FISH and qPCR were sensitive (both 100% and specific (93% and 89%, respectively to distinguish very short telomeres. However, qPCR sensitivity (40% and specificity (63% to detect telomeres below the tenth percentile were lower compared to flow-FISH (80% sensitivity and 85% specificity. In the clinical setting, flow-FISH was more accurate, reproducible, sensitive, and specific in the measurement of human

  9. A Direct inverse model to determine permeability fields from pressure and flow rate measurements

    NARCIS (Netherlands)

    Brouwer, G.K.; Fokker, P.A.; Wilschut, F.; Zijl, W.


    The determination of the permeability field from pressure and flow rate measurements in wells is a key problem in reservoir engineering. This paper presents a Double Constraint method for inverse modeling that is an example of direct inverse modeling. The method is used with a standard

  10. 76 FR 54373 - Airworthiness Directives; Austro Engine GmbH Model E4 Diesel Piston Engines (United States)


    ... Airworthiness Directives; Austro Engine GmbH Model E4 Diesel Piston Engines AGENCY: Federal Aviation..., contact Austro Engine GmbH, Rudolf-Diesel-Strasse 11, A-2700 Weiner Neustadt, Austria, phone: +43 2622... information, we estimate that this AD will affect about 32 model E4 diesel piston engines, installed on...

  11. 75 FR 68179 - Airworthiness Directives; Austro Engine GmbH Model E4 Diesel Piston Engines (United States)


    ... Airworthiness Directives; Austro Engine GmbH Model E4 Diesel Piston Engines AGENCY: Federal Aviation.... Affected ADs (b) None. Applicability (c) This AD applies to Austro Engine GmbH model E4 diesel piston.... Contact Austro Engine GmbH, Rudolf-Diesel- Strasse 11, A-2700 Weiner Neustadt, Austria, telephone: +43...

  12. 75 FR 19201 - Airworthiness Directives; Empresa Brasileira de Aeronautica S.A. (EMBRAER) Model ERJ 170... (United States)


    ... Airworthiness Directives; Empresa Brasileira de Aeronautica S.A. (EMBRAER) Model ERJ 170 Airplanes; and Model... Empresa Brasileira de Aeronautica S.A. (EMBRAER): Amendment 39-16261. Docket No. FAA-2009-1231... paragraphs (c)(1) and (c)(2) of this AD; certificated in any category. (1) Empresa Brasileira de Aeronautica...

  13. 75 FR 47190 - Airworthiness Directives; Empresa Brasileira de Aeronautica S.A. (EMBRAER) Model EMB-135... (United States)


    ... Airworthiness Directives; Empresa Brasileira de Aeronautica S.A. (EMBRAER) Model EMB-135 Airplanes; and Empresa.... The FAA amends Sec. 39.13 by adding the following new AD: 2010-16-02 Empresa Brasileira de Aeronautica...) None. Applicability (c) This AD applies to Empresa Brasileira de Aeronautica S.A. (EMBRAER) Model EMB...

  14. 76 FR 7511 - Airworthiness Directives; Empresa Brasileira de Aeronautica S.A. (EMBRAER) Model ERJ 170... (United States)


    ... Airworthiness Directives; Empresa Brasileira de Aeronautica S.A. (EMBRAER) Model ERJ 170 Airplanes; and Model.... For service information identified in this proposed AD, contact Empresa Brasileira de Aeronautica S.A... amends Sec. 39.13 by adding the following new AD: Empresa Brasileira de Aeronautica S.A. (EMBRAER...

  15. 75 FR 52263 - Airworthiness Directives; Empresa Brasileira de Aeronautica S.A. (EMBRAER) Model ERJ 170... (United States)


    ... Airworthiness Directives; Empresa Brasileira de Aeronautica S.A. (EMBRAER) Model ERJ 170 Airplanes; and Model... Empresa Brasileira de Aeronautica S.A. (EMBRAER): Amendment 39-16417. Docket No. FAA-2009-0497..., contact Empresa Brasileira de Aeronautica S.A. (EMBRAER), Technical Publications Section (PC 060), Av...

  16. 75 FR 12468 - Airworthiness Directives; Quartz Mountain Aerospace, Inc. Model 11E Airplanes (United States)


    ... Aerospace, Inc. Model 11E Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... airworthiness directive (AD) for all Quartz Mountain Aerospace, Inc. Model 11E airplanes. This proposed AD would... 5 p.m., Monday through Friday, except Federal holidays. Quartz Mountain Aerospace, Inc. is in...

  17. Disconfirming User Expectations of the Online Service Experience: Inferred versus Direct Disconfirmation Modeling. (United States)

    O'Neill, Martin; Palmer, Adrian; Wright, Christine


    Disconfirmation models of online service measurement seek to define service quality as the difference between user expectations of the service to be received and perceptions of the service actually received. Two such models-inferred and direct disconfirmation-for measuring quality of the online experience are compared (WebQUAL, SERVQUAL). Findings…

  18. A direct derivation of the exact Fisther information matrix of Gaussian vector state space models

    NARCIS (Netherlands)

    Klein, A.A.B.; Neudecker, H.


    This paper deals with a direct derivation of Fisher's information matrix of vector state space models for the general case, by which is meant the establishment of the matrix as a whole and not element by element. The method to be used is matrix differentiation, see [4]. We assume the model to be

  19. Introducing free-function camera calibration model for central-projection and omni-directional lenses (United States)

    Nekouei Shahraki, M.; Haala, N.


    To ensure making valid decisions with high accuracy in machine vision systems such as driver-assistant systems, a primary key factor is to have accurate measurements, which means that we need accurate camera calibration for various optical designs and a very fast approach to analyse the calibration data in real-time. Conventional methods have specific limitations such as limited accuracy, instability by using complex models, difficulties to model the local lens distortions and limitation in real-time calculations that altogether show the necessity to introduce new solutions. We introduce a new model for lens distortion modelling with high accuracies beyond conventional models while yet allowing real-time calculation. The concept is based on Free-Function modelling in a posterior calibration step using the initial distortion estimation and the corresponding residuals on the observations as input information. Free-Function model is the technique of numerically and locally modelling the lens distortion field by assuming unknown functions in our calibration model. This increases the model's flexibility to fit to different optical designs and be able to model the very local lens distortions. Using the Free-Function model one can observe great enhancements in accuracy (in comparison with classical models). Furthermore, by increasing the number of control points and improving their distribution the quality of lens modelling would be improved; a characteristic which is not present in the classical methods.

  20. Modeling phytoplankton community in reservoirs. A comparison between taxonomic and functional groups-based models. (United States)

    Di Maggio, Jimena; Fernández, Carolina; Parodi, Elisa R; Diaz, M Soledad; Estrada, Vanina


    In this paper we address the formulation of two mechanistic water quality models that differ in the way the phytoplankton community is described. We carry out parameter estimation subject to differential-algebraic constraints and validation for each model and comparison between models performance. The first approach aggregates phytoplankton species based on their phylogenetic characteristics (Taxonomic group model) and the second one, on their morpho-functional properties following Reynolds' classification (Functional group model). The latter approach takes into account tolerance and sensitivity to environmental conditions. The constrained parameter estimation problems are formulated within an equation oriented framework, with a maximum likelihood objective function. The study site is Paso de las Piedras Reservoir (Argentina), which supplies water for consumption for 450,000 population. Numerical results show that phytoplankton morpho-functional groups more closely represent each species growth requirements within the group. Each model performance is quantitatively assessed by three diagnostic measures. Parameter estimation results for seasonal dynamics of the phytoplankton community and main biogeochemical variables for a one-year time horizon are presented and compared for both models, showing the functional group model enhanced performance. Finally, we explore increasing nutrient loading scenarios and predict their effect on phytoplankton dynamics throughout a one-year time horizon. Copyright © 2015 Elsevier Ltd. All rights reserved.