WorldWideScience

Sample records for models based solely

  1. Modelling larval dispersal dynamics of common sole (Solea solea) along the western Iberian coast

    Science.gov (United States)

    Tanner, Susanne E.; Teles-Machado, Ana; Martinho, Filipe; Peliz, Álvaro; Cabral, Henrique N.

    2017-08-01

    Individual-based coupled physical-biological models have become the standard tool for studying ichthyoplankton dynamics and assessing fish recruitment. Here, common sole (Solea solea L.), a flatfish of high commercial importance in Europe was used to evaluate transport of eggs and larvae and investigate the connectivity between spawning and nursery areas along the western Iberian coast as spatio-temporal variability in dispersal and recruitment patterns can result in very strong or weak year-classes causing large fluctuations in stock size. A three-dimensional particle tracking model coupled to Regional Ocean Modelling System model was used to investigate variability of sole larvae dispersal along the western Iberian coast over a five-year period (2004-2009). A sensitivity analysis evaluating: (1) the importance of diel vertical migrations of larvae and (2) the size of designated recruitment areas was performed. Results suggested that connectivity patterns of sole larvae dispersal and their spatio-temporal variability are influenced by the configuration of the coast with its topographical structures and thus the suitable recruitment area available as well as the wind-driven mesoscale circulation along the Iberian coast.

  2. Effects of de-oiled palm kernel cake based fertilizers on sole maize ...

    African Journals Online (AJOL)

    A study was conducted to determine the effect of de-oiled palm kernel cake based fertilizer formulations on the yield of sole maize and cassava crops. Two de-oiled palm kernel cake based fertilizer formulations A and B were compounded from different proportions of de-oiled palm kernel cake, urea, muriate of potash and ...

  3. Robust design in generelaised linear models for improving the quality of polyurethane soles

    Directory of Open Access Journals (Sweden)

    Castro, Armando Mares

    2015-11-01

    Full Text Available In a process that manufactures polyurethane soles by casting, a number of problems lead to different types of defects on the sole, causing significant economic losses for the company. In order to improve the product quality and decrease the number of defects, this study conducts an experimental design in the context of robust design. Since the response variable is binary, the statistical analysis was performed using generalised linear models. The operational methodology reduced the percentage of defects, while combining the experimental technique and control systems to achieve superior quality and a consequent reduction in costs.

  4. Synthesis and characterization of cellulose nanocrystals as reinforcing agent in solely palm based polyurethane foam

    Science.gov (United States)

    Septevani, Athanasia Amanda; Annamalai, Pratheep K.; Martin, Darren J.

    2017-11-01

    The increasing awareness of the environment and the economy of petroleum resources has driven the development of alternative processes and raw materials based on sustainable and renewable biomaterials with excellent properties. This study is aimed to use biologically renewable cellulose nanocrystals (CNC) as reinforcing agent to enhance the properties of polyurethane foams (PUF) based on solely palm-polyol. Rod-like shape cellulose nanocrystals (CNC) was successfully isolated from cotton based resources via strong acid hydrolysis with the average width, length and aspect ratio about 14.7 ± 4.9 nm, 167.7 ± 23.2 nm and 11.4, respectively. The crystallinity of CNC was confirmed by using X-ray diffraction (XRD) and differential scanning calorimetry (DSC) and was found at 82.8% and 83.8%, respectively. This obtained cellulose nanocrystals (CNC) at a loading of 0.4 wt. % was then incorporated via solvent-free sonication method in the model of palm based polyurethane foam. The preliminary results showed that the effect of CNC on the mechanical properties afforded a significant improvement on the compressive strength and modulus without affecting much their tensile strength. The results on thermal stability and thermal transitions were found unchanged whereas the storage modulus revealed substantial improvement with the presence of CNC with almost two fold from 0.7 MPa to 1.3 MPa (˜86 %).

  5. Novel Thermal Analysis Model of the Foot-Shoe Sole Interface during Gait Motion

    Directory of Open Access Journals (Sweden)

    Yasuhiro Shimazaki

    2018-02-01

    Full Text Available Excessive heat at the foot-shoe sole interface negatively affects a human’s thermal comfort. An understanding of the thermal behavior at this interface is important for alleviating this discomfort. During gait motion, a human’s body weight cyclically compresses a shoe sole (commonly constructed of viscoelastic materials, generating heat during loading. To evaluate the thermal effects of this internal heat generation on foot comfort, we developed and empirically validated a thermal analysis model during gait motion. A simple, one-dimensional prediction model for heat conduction with heat generation during compressive loading was used. Heat generation was estimated as a function of the shoe sole’s material properties (e.g., elastic modulus and various gait parameters. When compared with experimental results, the proposed model proved effective in predicting thermal behavior at the foot-shoe sole interface under various conditions and shows potential for improving a human’s thermal comfort during gait motion through informed footwear design.

  6. Construction of a microsatellite-based genetic linkage map for half-smooth tongue sole Cynoglossus semilaevis

    Directory of Open Access Journals (Sweden)

    Wentao SONG, Guidong MIAO, Yongwei ZHAO, Yuze NIU, Renyi PANG, Xiaolin LIAO, Changwei SHAO, Songlin CHEN

    2013-02-01

    Full Text Available The half-smooth tongue sole Cynoglossus semilaevis is an important cultured marine fish and a promising model fish for the study of sex determination. Sex-specific genetic linkage maps of half-smooth tongue sole were developed with 567 markers (565 microsatellite markers and two SCAR markers. The parents and F1 progeny (92 individuals were used as segregating populations. The female map was composed of 480 markers in 21 linkage groups, covering a total of 1388.1 cM, with an average interval 3.06 cM between markers. The male map consisted of 417 markers in 21 linkage groups, spanning 1480.9 cM, with an average interval of 3.75 cM. The female and male maps had 474 and 416 unique positions, respectively. The genome length of half-smooth tongue sole was estimated to be 1522.9 cM for females and 1649.1cM for males. Based on estimations of map length, the female and male maps covered 91.1% and 89.8% of the genome, respectively. Furthermore, two female-specific SCAR markers, f-382 and f-783, were mapped on LG15f (linkage group 15 in female maps. The present study presents a mid-density genetic linkage map for half-smooth tongue sole. These improved genetic linkage maps may facilitate systematic genome searches to identify quantitative trait loci (QTL, such as disease resistance, growth and sex-related traits, and are very useful for marker-assisted selection breeding programs for economically important traits in half-smooth tongue sole [Current Zoology 59 (1: 99–108, 2013].

  7. Sole vibration improves locomotion through the recovery of joint movements in a mouse cast model.

    Directory of Open Access Journals (Sweden)

    Atsushi Doi

    Full Text Available We investigated the effects of a vibratory stimulus on the plantar surface of the hind limb for motor, sensory, and locomotive function using a mouse cast model. The right knee joint of C57BL/6 male mice (7 weeks, 20 g, n = 31 was flexed with aluminum splint and tape for 6 weeks. These mice were randomly divided into 2 groups (control group, n = 11 and vibration group, n = 12. The mice in the vibration group received vibration on the sole of the ankle for 15 minutes per day, 5 days per week. After the knee joint cast was removed, we measured the range of motion (ROM of both knee and ankle joints and the sensory threshold of the sole. Further, both walking and swimming movements were analyzed with a digital video. The sole vibration did not affect the passive ROM of the knee joint and sensory threshold after cast removal. However, it increased the ankle dorsiflexion range and improved free walking, swimming, and active movement of the knee joint. In conclusion, we show that the vibration recovered both walking and swimming movements, which resulted from improvements in both the passive ankle dorsiflexion and active knee movement.

  8. Habitat suitability for juvenile common sole (Solea solea, L.) in the Bay of Biscay (France): A quantitative description using indicators based on epibenthic fauna

    OpenAIRE

    Le Pape, Olivier; Baulier, Loic; Cloarec, Aurélie; Martin, Jocelyne; Le Loch, Francois; Desaunay, Yves

    2007-01-01

    This study describes the spatial distribution of young-of-the-year common sole based on beam trawl surveys conducted in late summer in the coastal and estuarine parts of the Bay of Biscay (France). Previous studies showed that habitat suitability for juvenile common sole varies according to physical factors and notably bathymetry and sediment structure. Nevertheless, the use of these descriptors alone to model habitat suitability led to considerable unexplained variability in juvenile common ...

  9. The development of a sole diet based on the composition of ragworm

    NARCIS (Netherlands)

    Kals, Jeroen

    2017-01-01

    Scientifically, this study aimed to validate the potential of ragworm to alleviate anaemia in common sole and to identify the dietary requirements of common sole to alleviate this anaemia. At the same time it was aimed to explain part of the difference in growth between sole fed a commercial pellet

  10. Surgical Debridement Is Superior to Sole Antibiotic Therapy in a Novel Murine Posttraumatic Osteomyelitis Model.

    Directory of Open Access Journals (Sweden)

    Johannes Maximilian Wagner

    Full Text Available Bone infections after trauma, i.e. posttraumatic osteomyelitis, pose one of the biggest problems of orthopedic surgery. Even after sufficient clinical therapy including vast debridement of infected bone and antibiotic treatment, regeneration of postinfectious bone seems to be restricted. One explanation includes the large sized defects resulting from sufficient debridement. Furthermore, it remains unclear if inflammatory processes after bone infection do affect bone regeneration. For continuing studies in this field, an animal model is needed where bone regeneration after sufficient treatment can be studied in detail.For this purpose we created a stable infection in murine tibiae by Staphylococcus aureus inoculation. Thereafter, osteomyelitic bones were debrided thoroughly and animals were subsequently treated with antibiotics. Controls included debrided, non-infected, as well as infected animals exclusively treated with antibiotics. To verify sufficient treatment of infected bone, different assessments detecting S. aureus were utilized: agar plates, histology and RT-qPCR.All three detection methods revealed massive reduction or eradication of S. aureus within debrided bones 1 and 2 weeks postoperatively, whereas sole antibiotic therapy could not provide sufficient treatment of osteomyelitic bones. Debrided, previously infected bones showed significantly decreased bone formation, compared to debrided, non-infected controls.Thus, the animal model presented herein provides a reliable and fascinating tool to study posttraumatic osteomyelitis for clinical therapies.

  11. Hyperbaric Oxygen Therapy as a Sole Agent Is Not Immunosuppressant in a Highly Immunogenic Mouse Model

    Directory of Open Access Journals (Sweden)

    Adam Gassas

    2011-01-01

    Full Text Available Background. Hyperbaric oxygen (HBO therapy, which is used for many conditions, may also have immunosuppressive effects and could be used for prevention or treatment of graft-versus-host disease (GvHD. If HBO is immunosuppressant, then we hypothesize that HBO therapy will delay the T-cell mediated skin graft rejection. Methods. C57/BL6 black-coated (H2B mice received skin graft from CBA (H2D white-coated mice. Mice were treated with either 19 session of 240 kpa oxygen or 29 session of 300 kpa oxygen, for 90 minutes. Mice were housed either 4 per cage or separately, to prevent friction and mechanical factors that may affect graft survival. Skin grafts were assessed daily. Results. There was no difference in length of graft survival between mice that received either regimens of HBO therapy and mice that did not receive HBO therapy. Conclusions. HBO therapy, as a sole agent, did not delay skin graft rejection in a highly immunogenic mouse model.

  12. Assessment of children with learning and behavioural problems: comparison of a multidisciplinary and sole paediatrician model.

    Science.gov (United States)

    Mittal, Riju; Sciberras, Emma; Sewell, Jill; Efron, Daryl

    2014-02-01

    This study aimed to compare multidisciplinary (MD) versus sole paediatrician (SP) assessment models for children with learning and/or behaviour difficulties. Children aged 4-12 years referred for an MD or SP assessment of learning and/or behavioural concerns were invited to participate. At baseline, parents completed surveys assessing child behaviour (Strengths and Difficulties Questionnaire; SDQ) and quality of life (QoL) (Pediatric Quality of Life Inventory 4.0; PedsQL). Following the assessment, parents completed a survey evaluating their satisfaction with the assessment. Parents completed a survey at 3-4 months post-assessment assessing: (i) adherence to recommendations; (ii) perceived changes in child functioning; and (iii) child QoL and behaviour. The parents of 66 children (82% male) participated in the study. Parents reported satisfaction with both assessment models; however, parents in the MD group reported better understanding of their child's difficulties than the SP group (P = 0.03). Parents in the MD group were less likely to report that 'recommendations were useful and practical' compared with the SP group (P = 0.01). There was no significant change in child behaviour or QoL in either group from baseline to 3-4 months post-assessment. Parents attending both clinics were satisfied with the assessment process. MD assessment of children with suspected learning and/or behavioural concerns appears to have the additional benefit of helping families to better understand their child's difficulties. Fewer families attending MD clinics reported that recommendations were useful and practical compared with the SP model. © 2013 The Authors. Journal of Paediatrics and Child Health © 2013 Paediatrics and Child Health Division (Royal Australasian College of Physicians).

  13. First policy then science: why a management unit based solely on genetic criteria cannot work.

    Science.gov (United States)

    Taylor, B L; Dizon, A E

    1999-12-01

    In contrast to the goals of the symposium from which this series of papers originated, we argue that attempts to apply unambiguously defined and general management unit criteria based solely on genetic parameters can easily lead to incorrect management decisions. We maintain that conservation genetics is best served by altering the perspective of data analysis so that decision making is optimally facilitated. To do so requires accounting for policy objectives early in the design and execution of the science. This contrasts with typical hypothesis testing approaches to analysing genetic data for determining population structure, which often aspire to objectivity by considering management objectives only after the analysis is complete. The null hypothesis is generally taken as panmixia with a strong predilection towards avoiding false acceptance of the alternative hypothesis (the existence of population structure). We show by example how defining management units using genetic data and standard scientific analyses that do not consider either the specific management objectives or the anthropogenic risks facing the populations being studied can easily result in a management failure by losing local populations. We then use the same example to show how an 'applied' approach driven by specific objectives and knowledge of abundance and mortality results in appropriate analyses and better decisions. Because management objectives stem from public policy, which differs among countries and among species groups, criteria for defining management units must be specific, not general. Therefore, we conclude that the most productive way to define management units is on a case-by-case basis. We also suggest that creating analytical tools designed specifically to address decision making in a management context, rather than re-tooling academic tools designed for other purposes, will increase and improve the use of genetics in conservation.

  14. Modeled connectivity between northern rock sole (Lepidopsetta polyxystra) spawning and nursery areas in the eastern Bering Sea

    Science.gov (United States)

    Cooper, D. W.; Duffy-Anderson, J. T.; Stockhausen, W. T.; Cheng, W.

    2013-11-01

    Connectivity between spawning and potential nursery areas of northern rock sole, Lepidopsetta polyxystra, in the eastern Bering Sea was examined using an individual-based biophysical-coupled model. Presumed spawning areas were identified using historical field-collected ichthyoplankton data, and nursery habitats were characterized based on previously described settlement areas. Simulated larvae were released from spawning areas near the Pribilof Islands, south of the Pribilof Islands along the outer continental shelf, on the north side of the Alaska Peninsula, and in the Gulf of Alaska south of Unimak Island. Simulated larvae were transported along two general pathways: 1) northwards along the outer continental shelf from Unimak Island towards the Pribilof Islands and further north offshore of mainland Alaska, and 2) eastward along the Alaska Peninsula. At the end of the 2-month simulation, drift pathways placed pre-settlement stage larvae offshore of known nursery areas of older juveniles near mainland Alaska, consistent with a hypothesis that initial settlement may be followed by substantial post-settlement redistribution.

  15. A HUBBLE DIAGRAM FROM TYPE II SUPERNOVAE BASED SOLELY ON PHOTOMETRY: THE PHOTOMETRIC COLOR METHOD

    Energy Technology Data Exchange (ETDEWEB)

    De Jaeger, T.; González-Gaitán, S.; Galbany, L.; Hamuy, M.; Gutiérrez, C. P.; Kuncarayakti, H. [Millennium Institute of Astrophysics, Santiago (Chile); Anderson, J. P. [European Southern Observatory, Alonso de Córdova 3107, Casilla 19, Santiago (Chile); Phillips, M. M.; Campillay, A.; Castellón, S.; Hsiao, E. Y.; Morrell, N. [Las Campanas Observatory, Carnegie Observatories, Casilla 601, La Serena (Chile); Stritzinger, M. D.; Contreras, C. [Department of Physics and Astronomy, Aarhus University, Ny Munkegade 120, DK-8000 Aarhus C (Denmark); Bolt, L. [Argelander Institut für Astronomie, Universität Bonn, Auf dem Hgel 71, D-53111 Bonn (Germany); Burns, C. R. [Observatories of the Carnegie Institution for Science, Pasadena, CA 91101 (United States); Folatelli, G. [Instituto de Astrofísica de La Plata, CONICET, Paseo del Bosque S/N, B1900FWA, La Plata (Argentina); Freedman, W. L. [Department of Astronomy and Astrophysics, University of Chicago, Chicago, IL 60637 (United States); Krisciunas, K. [George P. and Cynthia Woods Mitchell Institute for Fundamental Physics and Astronomy, Department of Physics and Astronomy, Texas A and M University, College Station, TX 77843 (United States); Krzeminski, W., E-mail: dthomas@das.uchile.cl [N. Copernicus Astronomical Center, ul. Bartycka 18, 00-716 Warszawa (Poland); and others

    2015-12-20

    We present a Hubble diagram of SNe II using corrected magnitudes derived only from photometry, with no input of spectral information. We use a data set from the Carnegie Supernovae Project I for which optical and near-infrared light curves were obtained. The apparent magnitude is corrected by two observables, one corresponding to the slope of the plateau in the V band and the second a color term. We obtain a dispersion of 0.44 mag using a combination of the (V − i) color and the r band and we are able to reduce the dispersion to 0.39 mag using our golden sample. A comparison of our photometric color method (PCM) with the standardized candle method (SCM) is also performed. The dispersion obtained for the SCM (which uses both photometric and spectroscopic information) is 0.29 mag, which compares with 0.43 mag from the PCM for the same SN sample. The construction of a photometric Hubble diagram is of high importance in the coming era of large photometric wide-field surveys, which will increase the detection rate of supernovae by orders of magnitude. Such numbers will prohibit spectroscopic follow up in the vast majority of cases, and hence methods must be deployed which can proceed using solely photometric data.

  16. Evaluating Bagasse-Based Ration as a Sole Feed for Goats

    African Journals Online (AJOL)

    Nafiisah

    Sugarcane bagasse was used with other locally available ingredients to constitute a complete ration, bagasse-based feed (BBF) for ruminants. The effect of the feed on rumen pH and ammonia was studied. The effect of the feed on intake and live weight gain in goats was also determined in a growth trial. At the end of the.

  17. Regression model for the study of sole and cumulative effect of ...

    African Journals Online (AJOL)

    The effect of variability in temperature, solar radiation and photothermal quotient were studied under varying planting windows in three wheat genotypes to cope environmental vulnerability. Regression models are regarded as valuable tools for the evaluation of temperature, solar radiation and photothermal quotient effects ...

  18. Modelling the spatial distribution of plaice ( Pleuronectes platessa), sole ( Solea solea) and thornback ray ( Raja clavata) in UK waters for marine management and planning

    Science.gov (United States)

    Maxwell, D. L.; Stelzenmüller, V.; Eastwood, P. D.; Rogers, S. I.

    2009-04-01

    Species distribution maps are needed for ecosystem-based marine management including the development of marine spatial plans. If such maps are based on predictive models then modelling procedures should aim to maximise validation success, and any uncertainty in the predictions needs to be made explicit. We developed a predictive modelling approach to produce robust maps of the distributions of selected marine species at a regional scale. We used 14 years of survey data to map the distributions of plaice, sole and thornback ray in three hydrographic regions comprising parts of the Irish Sea, Celtic Sea and the English Channel with the help of the hybrid technique regression kriging, which combines regression models with geostatistical tools. For each species-region combination we constructed logistic Generalized Linear Models (GLMs) based on presence-absence data using the environmental variables: depth, bottom temperature, bed shear stress and sediment type, as predictors. We selected GLMs using the mean squared error of prediction (MSEP) estimated by cross-validation then conducted a geostatistical analysis of the residuals to incorporate spatial structure in the predictions. In general, we found that species occurrence was positively related to shallow areas, a bed shear stress of between 0 and 1.5 N/m 2, and the presence of sandy sediment. Predicted species occurrence probabilities were in good agreement with survey observations. This modelling framework selects environmental models based on predictive ability and considers the effect of spatial autocorrelation on predictions, together with the simultaneous presentation of observations, associated uncertainties, and predictions. The potential benefit of these distribution maps to marine management and planning is discussed.

  19. EPA Sole Source Aquifers

    Data.gov (United States)

    U.S. Environmental Protection Agency — Information on sole source aquifers (SSAs) is widely used in assessments under the National Environmental Policy Act and at the state and local level. A national...

  20. SoleSound

    DEFF Research Database (Denmark)

    Zanotto, Damiano; Turchet, Luca; Boggs, Emily Marie

    2014-01-01

    This paper introduces the design of SoleSound, a wearable system designed to deliver ecological, audio-tactile, underfoot feedback. The device, which primarily targets clinical applications, uses an audio-tactile footstep synthesis engine informed by the readings of pressure and inertial sensors...

  1. ELIMINATION OF CAREEN OF THE BASE A GEOTECHNICAL SIDE JOB OF THE SOIL BASIS UNDER ITS SOLE

    Directory of Open Access Journals (Sweden)

    V. I. Chaplyhin

    2010-03-01

    Full Text Available The geomechanical design model of soil base, corresponding to the physical state of soils (underworked by horizontal cylindrical boreholes under the strip foundation, is offered. The block diagram of device for control of parameters of the system «underworked soil base – strip foundation with tilt» is presented. The unforeseen circumstances of technological and organizational character, which influence on the stressed-and-strained state of the system «base – foundation – superstructure» can arise during the elimination of excessive tilts of buildings and structures. Therefore it is necessary to have trustworthy information about the actual stressed-and-strained state of an object during making such works. The automated measurement-and-information system has been developed and widely applied for conducting the real time monitoring. The technical means of system include: inductive gauges, instruments for inductance measurements, information-gathering block and communication lines. Numerical modeling of the stressed-and-strained state of buildings and structures with use of the automated measurement-andinformation system and program complex «Geotekhnika» [1] allows correcting the project during the elimination of excessive tilts and controlling the technological settlements in order to reduce a risk.

  2. On the autarchic use of solely PIXE data in particulate matter source apportionment studies by receptor modeling

    Energy Technology Data Exchange (ETDEWEB)

    Lucarelli, F. [Department of Physics and Astronomy, University of Florence, Via G. Sansone 1, 50019 Sesto Fiorentino (Italy); National Institute of Nuclear Physics (INFN)-Florence, Via G. Sansone 1, 50019 Sesto Fiorentino (Italy); Nava, S., E-mail: nava@fi.infn.it [National Institute of Nuclear Physics (INFN)-Florence, Via G. Sansone 1, 50019 Sesto Fiorentino (Italy); Calzolai, G. [Department of Physics and Astronomy, University of Florence, Via G. Sansone 1, 50019 Sesto Fiorentino (Italy); Chiari, M. [National Institute of Nuclear Physics (INFN)-Florence, Via G. Sansone 1, 50019 Sesto Fiorentino (Italy); Giannoni, M.; Traversi, R.; Udisti, R. [Department of Chemistry, University of Florence, Via della Lastruccia 3, 50019 Sesto Fiorentino (Italy)

    2015-11-15

    Particle Induced X-ray Emission (PIXE) analysis of aerosol samples allows simultaneous detection of several elements, including important tracers of many particulate matter sources. This capability, together with the possibility of analyzing a high number of samples in very short times, makes PIXE a very effective tool for source apportionment studies by receptor modeling. However, important aerosol components, like nitrates, OC and EC, cannot be assessed by PIXE: this limitation may strongly compromise the results of a source apportionment study if based on PIXE data alone. In this work, an experimental dataset characterised by an extended chemical speciation (elements, EC–OC, ions) is used to test the effect of reducing input species in the application of one of the most widely used receptor model, namely Positive Matrix Factorization (PMF). The main effect of using only PIXE data is that the secondary nitrate source is not identified and the contribution of biomass burning is overestimated, probably due to the similar seasonal pattern of these two sources.

  3. SOLE: enhanced FIA data analysis capabilities

    Science.gov (United States)

    Michael Spinney; Paul Van Deusen

    2009-01-01

    The Southern On Line Estimator (SOLE), is an Internet-based annual forest inventory and analysis (FIA) data analysis tool developed cooperatively by the National Council for Air and Stream Improvement and the Forest Service, U.S. Department of Agriculture's Forest Inventory and Analysis program at the Southern Research Station. Recent development of SOLE has...

  4. Tidally distorted exoplanets: Density corrections for short-period hot-Jupiters based solely on observable parameters

    Energy Technology Data Exchange (ETDEWEB)

    Burton, J. R.; Watson, C. A.; Fitzsimmons, A.; Moulds, V. [Astrophysics Research Centre, Queen' s University Belfast, Belfast BT7 1NN (United Kingdom); Pollacco, D.; Wheatley, P. J. [Department of Physics and Astronomy, University of Warwick, Coventry CV4 7AL (United Kingdom); Littlefair, S. P., E-mail: jburton04@qub.ac.uk [Department of Physics and Astronomy, University of Sheffield, Sheffield S3 7RH (United Kingdom)

    2014-07-10

    The close proximity of short-period hot-Jupiters to their parent star means they are subject to extreme tidal forces. This has a profound effect on their structure and, as a result, density measurements that assume that the planet is spherical can be incorrect. We have simulated the tidally distorted surface for 34 known short-period hot-Jupiters, assuming surfaces of constant gravitational equipotential for the planet, and the resulting densities have been calculated based only on observed parameters of the exoplanet systems. Comparing these results to the density values, assuming the planets are spherical, shows that there is an appreciable change in the measured density for planets with very short periods (typically less than two days). For one of the shortest-period systems, WASP-19b, we determine a decrease in bulk density of 12% from the spherical case and, for the majority of systems in this study, this value is in the range of 1%-5%. On the other hand, we also find cases where the distortion is negligible (relative to the measurement errors on the planetary parameters) even in the cases of some very short period systems, depending on the mass ratio and planetary radius. For high-density gas planets requiring apparently anomalously large core masses, density corrections due to tidal deformation could become important for the shortest-period systems.

  5. EPA Region 1 Sole Source Aquifers

    Data.gov (United States)

    U.S. Environmental Protection Agency — This coverage contains boundaries of EPA-approved sole source aquifers. Sole source aquifers are defined as an aquifer designated as the sole or principal source of...

  6. Tax Policy and Sole Proprietorships: A Closer Look

    OpenAIRE

    Nelson, Susan C.

    2008-01-01

    The 21 million sole proprietorship returns filed in 2005 represent a wide variety of economic activity. This paper examines three major tax policy issues related to sole proprietorships—taxpayer compliance, taxpayer burden, and incentives for growth. It uses tax return data to take a closer look at sole proprietorships. It proposes a new taxonomy for describing these returns in an economically meaningful way, based on the principal factors of production that they use: their own labor, hired l...

  7. A NEW DESIGN METHOD FOR FLAT FOOTWEAR SOLES

    Directory of Open Access Journals (Sweden)

    IONESCU Cozmin

    2016-05-01

    Full Text Available Carried research regarding footwear soles reveald that by moulding footwear details can be obtained in a wide variety of models. Shoe soles are complex three dimensional objects and for attaching them with the uppers, the interor countour of the soles has to correspond to the featherline contour of the last. That’s why, is necessary that soles design to be done with high accuracy and in strict accordance to the last. Nowadays, there are specialized software applications which can perform various computer aided design processes for footwear. Among the high performance systems used for the design of footwear soles and injection moulds for shoe soles, we may mention: Delcam Shoe Solution, Delcam PowerSHAPE-e, Padsy II and Padsy III, Shoe Master System, Lectra System, Parmel System and ATOS II System. This paper presents a 3D design method, developed by the authors, for footwear flat soles using PowerSHAPE-e software programm from of Delcam Crispin. The computer-aided design technique used in this paper highlights several important advantages that include: increased design quality; three dimensional viewing of soles, which can lead to immediate decisions, regarding the acceptance of newly developed models; it can be appreciated the complexity of mould cavities execution, without the need of making prototypes; the outlines of construction templates are accurately obtained for the mould cavities and for all size numbers; calculations can easily be done for determining the soles volume for the entire size number, with implications on estimating polymer blend consumption and so on.

  8. An Individual-based Probabilistic Model for Fish Stock Simulation

    Directory of Open Access Journals (Sweden)

    Federico Buti

    2010-08-01

    Full Text Available We define an individual-based probabilistic model of a sole (Solea solea behaviour. The individual model is given in terms of an Extended Probabilistic Discrete Timed Automaton (EPDTA, a new formalism that is introduced in the paper and that is shown to be interpretable as a Markov decision process. A given EPDTA model can be probabilistically model-checked by giving a suitable translation into syntax accepted by existing model-checkers. In order to simulate the dynamics of a given population of soles in different environmental scenarios, an agent-based simulation environment is defined in which each agent implements the behaviour of the given EPDTA model. By varying the probabilities and the characteristic functions embedded in the EPDTA model it is possible to represent different scenarios and to tune the model itself by comparing the results of the simulations with real data about the sole stock in the North Adriatic sea, available from the recent project SoleMon. The simulator is presented and made available for its adaptation to other species.

  9. Reliable measurement of 3D foot bone angles based on the frame-of-reference derived from a sole of the foot

    Science.gov (United States)

    Kim, Taeho; Lee, Dong Yeon; Park, Jinah

    2016-03-01

    Clinical management of foot pathology requires accurate and robust measurement of the anatomical angles. In order to measure a 3D angle, recent approaches have adopted a landmark-based local coordinate system to establish bone angles used in orthopedics. These measurement methods mainly assess the relative angle between bones using a representative axis derived from the morphological feature of the bone and therefore, the results can be affected by bone deformities. In this study, we propose a method of deriving a global frame-of-reference to acquire consistent direction of the foot by extracting the undersurface of the foot from the CT image data. The two lowest positions of the foot skin are identified from the surface to define the base plane, and the direction from the hallux to the fourth toe is defined together to construct the global coordinate system. We performed the experiment on 10 volumes of foot CT images of healthy subjects to verify that the proposed method provides reliable measurements. We measured 3D angles for talus-calcaneus and talus-navicular using facing articular surfaces of paired bones. The angle was reported in 3 projection angles based on both coordinate systems defined by proposed global frame-of-reference and by CT image planes (saggital, frontal, and transverse). The result shows that the quantified angle using the proposed method considerably reduced the standard deviation (SD) against the angle using the conventional projection planes, and it was also comparable with the measured angles obtained from local coordinate systems of the bones. Since our method is independent from any individual local shape of a bone, unlike the measurement method using the local coordinate system, it is suitable for inter-subject comparison studies.

  10. Synthesis, structures and magnetic properties in 3d-electron-rich isostructural complexes based on chains with sole syn-anti carboxylate bridges.

    Science.gov (United States)

    Su, Feng; Lu, Liping; Feng, Sisi; Zhu, Miaoli; Gao, Zengqiang; Dong, Yuhui

    2015-04-28

    To evaluate magnetic properties of isostructural compounds, a series of 3D carboxylate coordination polymers [M(H2bpta)]n, (H4bpta = 2,2',4,4'-biphenyltetracarboxylic acid, M = Fe(II) (1), Ni(II) (2), Cu(II) (3) and Zn(II) (4)), was synthesized in H2O-CH3CN or H2O solvents, respectively. Structurally, complexes 1-4 have isostructural features with (5,5)-connected 3D framework, wherein the M(II) centre takes an octahedral coordination environment consisting of six oxygen atoms from carboxylates of ligands. The M(II) sites are linked by syn-anti carboxylates to form chains with an M···M separation of 4.880(2) (M = Fe), 4.784(2) (M = Ni), 4.541(2) (M = Cu), and 4.607(2) Å (M = Zn), respectively. The shortest M···M distances between interchains locate 9.122(4), 9.077(3), 9.361(3), and 8.767(2) Å, respectively. Magnetically, the isostructural polymers show different magnetic behaviors due to different spins of central ions. Theoretical analysis indicates that couplings between magnetic ions obey uniform chain models. The magnetic susceptibility of 1 and 2 are perfectly fitted by the modified Fisher model to yield an effective intra-chain exchange coupling constant of -0.81(1) and 3.67(2) cm(-1), respectively. For 3, a Heisenberg ferromagnetic S = 1/2 chain included the intra-chain magnetic exchange interaction (J = 9.28(1) cm(-1), and zj' = -0.068(3) cm(-1)), weak ferromagnetic interactions in intra-chains, and weak antiferromagnetic interactions between interchains. The phenomena of 1-3 accord with the common view that the exchange interaction between two magnetic M(II) ions bridged by the syn-anti carboxylate bridge is dominantly weak ferro- or anti-ferromagnetic interactions. In addition, the M-O-C-O-M spin exchange interactions |J| of M2(CO2)2 (M = Mn(3d(5))(20), Fe(3d(6)), Co(3d(7))(20), Ni(3d(8)), Cu(3d(9))) decrease in strength with Cu2(CO2)2 > Ni2(CO2)2 > Co2(CO2)2 > Fe2(CO2)2 > Mn2(CO2)2, consistent with orbit order.

  11. EPA Region 1 Sole Source Aquifers

    Science.gov (United States)

    This coverage contains boundaries of EPA-approved sole source aquifers. Sole source aquifers are defined as an aquifer designated as the sole or principal source of drinking water for a given aquifer service area; that is, an aquifer which is needed to supply 50% or more of the drinking water for the area and for which there are no reasonable alternative sources should the aquifer become contaminated.The aquifers were defined by a EPA hydrogeologist. Aquifer boundaries were then drafted by EPA onto 1:24000 USGS quadrangles. For the coastal sole source aquifers the shoreline as it appeared on the quadrangle was used as a boundary. Delineated boundaries were then digitized into ARC/INFO.

  12. Sole risk and non-consent

    International Nuclear Information System (INIS)

    Winsor, Tom

    1994-01-01

    This article discusses the subjects of sole risk and non-consent in joint operation agreements as used by oil and gas joint ventures in the United Kingdom. The difference between these two concepts is examined in detail. (UK)

  13. A NEW 3D DESIGN METHOD FOR FOOTWEAR SOLES USING DELCAM PowerSHAPE-e SYSTEM

    Directory of Open Access Journals (Sweden)

    IONESCU Cozmin

    2016-05-01

    Full Text Available Design methods of soles and soles injection moulds must be accurate, timely and at the same time, accessible to a wide category of soles and injection moulds designers and manufacturers. For designing soles and injection moulds for soles, various dedicated CAD/CAM systems have been developed, such as: Delcam Shoe Solution (3D, Delcam PowerSHAPE-e (2D and 3D, Padsy II (2D and Padsy III (3D, Shoemaster System (2D and 3D, Lectra System (2D and 3D, Parmel System (2D and ATOS II System (3D. These systems are equipped with colour displays, plotters, digitizers, terminals and other equipment dedicated for computer aided design activities. Designing 3D soles models using computer systems enables the prevention of ambiguities inherited from 2D drawings, thus reducing errors and remanufacturing. Depending on the design complexity of soles, the technical means available for copying shoe soles and the technologies at the disposal of the soles manufacturers, soles and injection moulds designers adopt various design methods. Not all CAD/CAM systems are accessible for all users, because often their purchasing costs are high. Design method developed and presented in this paper, uses Delcam PowerSHAPE software program, which has the advantage that it can be accessed free of charge from the manufacturer's website. At the same time, this software program provides the user with all the necessary tools and instruments needed to design the most complex injection moulds and footwear sole.

  14. Effect of wind blows on the transport and settlement of brown sole ( Pleuronectes herzensteini) larvae in a shelf region of the Sea of Japan: numerical experiments with an Euler-Lagrangian model

    Science.gov (United States)

    Nakata, H.; Fujihara, M.; Suenaga, Y.; Nagasawa, T.; Fujii, T.

    2000-10-01

    The transportation of eggs and larvae of brown sole in a shelf region of the Sea of Japan was explored using a 3D Euler-Lagrangian model, with special interest in the effect of wind blows on the larval retention. The general pattern of egg and larval transport from the spawning ground to the nursery was well reproduced under a constant westerly wind (4 m s -1), by assuming vertical movement of the eggs and larvae (upward in the earlier phase and downward in the later phase of the drift period). Using this model, the effect of westerly wind speed on egg and larval retention in the shelf was evaluated, and it was shown that when the wind speed exceeded a critical value (>5 m s -1), the retention rate could be rapidly reduced. An exploratory simulation of the effect of a one-day westerly blow with a speed of 15 m s -1 on the retention further indicated that the westerly blow induced strong offshore drift of the shelf water at the subsurface, and that it could markedly reduce the retention rate in the earlier phase of the drift period when eggs stay in the lower layer, and in the final phase when larvae stay near the bottom before settlement. The numbers of juveniles which successfully settled on the nursery in the study area showed a significant negative correlation with the frequency of strong westerlies in April. This suggests that wind blows could seriously reduce the retention of the larvae just before settlement, providing field evidence to support the model results. Recent declines in the fishery catch can therefore be partly explained by recruitment failure due to the increase in the frequency of strong westerly blows.

  15. Web Based VRML Modelling

    NARCIS (Netherlands)

    Kiss, S.; Sarfraz, M.

    2004-01-01

    Presents a method to connect VRML (Virtual Reality Modeling Language) and Java components in a Web page using EAI (External Authoring Interface), which makes it possible to interactively generate and edit VRML meshes. The meshes used are based on regular grids, to provide an interaction and modeling

  16. Web Based VRML Modelling

    NARCIS (Netherlands)

    Kiss, S.; Banissi, E.; Khosrowshahi, F.; Sarfraz, M.; Ursyn, A.

    2001-01-01

    Presents a method to connect VRML (Virtual Reality Modeling Language) and Java components in a Web page using EAI (External Authoring Interface), which makes it possible to interactively generate and edit VRML meshes. The meshes used are based on regular grids, to provide an interaction and modeling

  17. Dual structures for the sole-proprietorship firm

    OpenAIRE

    Chambers, Robert G.; Quiggin, John

    2003-01-01

    This paper presents a dual representation of firm-level and market-level equilibrium behavior for a sole proprietorship economy with competitive and frictionless financial markets and stochastic production opportunities in a two-period setting. The dual equilibrium model is used to state conditions for the firms' production choices to be independent of their risk preferences in equilibrium. These conditions entail Pareto optimality, but do not require either that the firm's consumption choice...

  18. Size selectivity of sole gill nets fished in the North Sea

    DEFF Research Database (Denmark)

    Madsen, Niels; Holst, René; Wileman, D.

    1999-01-01

    The size selectivity of sole nets was measured indirectly on a Danish commercial gill net vessel in the North Sea by using nets made in seven different mesh sizes fished simultaneously. Maximum likelihood procedure was used to fit different forms for the selection curve to the catch data for sole.......28 for sole, 2.60 for plaice and 4.56 for cod. Selection curves were also fitted to the catch data pooled over all sets. The model deviance for the sole and plaice data indicated lack of lit when pooling the catch data. (C) 1999 Elsevier Science B.V. All rights reserved....

  19. A genetic linkage map of sole (Solea solea: a tool for evolutionary and comparative analyses of exploited (flatfishes.

    Directory of Open Access Journals (Sweden)

    Eveline Diopere

    Full Text Available Linkage maps based on markers derived from genes are essential evolutionary tools for commercial marine fish to help identify genomic regions associated with complex traits and subject to selective forces at play during exploitation or selective breeding. Additionally, they allow the use of genomic information from other related species for which more detailed information is available. Sole (solea solea L. is a commercially important flatfish species in the North Sea, subject to overexploitation and showing evidence of fisheries-induced evolutionary changes in growth- and maturation-related traits. Sole would definitely benefit from a linkage map to better understand how evolution has shaped its genome structure. This study presents a linkage map of sole based on 423 single nucleotide polymorphisms derived from expressed sequence tags and 8 neutral microsatellite markers. The total map length is 1233.8 cM and consists of 38 linkage groups with a size varying between 0 to 92.1 cM. Being derived from expressed sequence tags allowed us to align the map with the genome of four model fish species, namely medaka (Oryzias latipes, Nile tilapia (Oreochromis niloticus, three-spined stickleback (Gasterosteus aculeatus and green spotted pufferfish (Tetraodon nigroviridis. This comparison revealed multiple conserved syntenic regions with all four species, and suggested that the linkage groups represent 21 putative sole chromosomes. The map was also compared to the linkage map of turbot (Scophthalmus maximus, another commercially important flatfish species and closely related to sole. For all putative sole chromosomes (except one a turbot homolog was detected, confirming the even higher degree of synteny between these two flatfish species.

  20. Model Based Temporal Reasoning

    Science.gov (United States)

    Rabin, Marla J.; Spinrad, Paul R.; Fall, Thomas C.

    1988-03-01

    Systems that assess the real world must cope with evidence that is uncertain, ambiguous, and spread over time. Typically, the most important function of an assessment system is to identify when activities are occurring that are unusual or unanticipated. Model based temporal reasoning addresses both of these requirements. The differences among temporal reasoning schemes lies in the methods used to avoid computational intractability. If we had n pieces of data and we wanted to examine how they were related, the worst case would be where we had to examine every subset of these points to see if that subset satisfied the relations. This would be 2n, which is intractable. Models compress this; if several data points are all compatible with a model, then that model represents all those data points. Data points are then considered related if they lie within the same model or if they lie in models that are related. Models thus address the intractability problem. They also address the problem of determining unusual activities if the data do not agree with models that are indicated by earlier data then something out of the norm is taking place. The models can summarize what we know up to that time, so when they are not predicting correctly, either something unusual is happening or we need to revise our models. The model based reasoner developed at Advanced Decision Systems is thus both intuitive and powerful. It is currently being used on one operational system and several prototype systems. It has enough power to be used in domains spanning the spectrum from manufacturing engineering and project management to low-intensity conflict and strategic assessment.

  1. Improving Quality of Shoe Soles Product using Six Sigma

    Science.gov (United States)

    Jesslyn Wijaya, Athalia; Trusaji, Wildan; Akbar, Muhammad; Ma’ruf, Anas; Irianto, Dradjad

    2018-03-01

    A manufacture in Bandung produce kind of rubber-based product i.e. trim, rice rollers, shoe soles, etc. After penetrating the shoe soles market, the manufacture has met customer with tight quality control. Based on the past data, defect level of this product was 18.08% that caused the manufacture’s loss of time and money. Quality improvement effort was done using six sigma method that included phases of define, measure, analyse, improve, and control (DMAIC). In the design phase, the object’s problem and definition were defined. Delphi method was also used in this phase to identify critical factors. In the measure phase, the existing process stability and sigma quality level were measured. Fishbone diagram and failure mode and effect analysis (FMEA) were used in the next phase to analyse the root cause and determine the priority issues. Improve phase was done by designing alternative improvement strategy using 5W1H method. Some improvement efforts were identified, i.e. (i) modifying design of the hanging rack, (ii) create pantone colour book and check sheet, (iii) provide pedestrian line at compound department, (iv) buying stop watch, and (v) modifying shoe soles dies. Some control strategies for continuous improvement were proposed such as SOP or reward and punishment system.

  2. Climate-based species distribution models for Armillaria solidipes in Wyoming: A preliminary assessment

    Science.gov (United States)

    John W. Hanna; James T. Blodgett; Eric W. I. Pitman; Sarah M. Ashiglar; John E. Lundquist; Mee-Sook Kim; Amy L. Ross-Davis; Ned B. Klopfenstein

    2014-01-01

    As part of an ongoing project to predict Armillaria root disease in the Rocky Mountain zone, this project predicts suitable climate space (potential distribution) for A. solidipes in Wyoming and associated forest areas at risk to disease caused by this pathogen. Two bioclimatic models are being developed. One model is based solely on verified locations of A. solidipes...

  3. Skull base tumor model.

    Science.gov (United States)

    Gragnaniello, Cristian; Nader, Remi; van Doormaal, Tristan; Kamel, Mahmoud; Voormolen, Eduard H J; Lasio, Giovanni; Aboud, Emad; Regli, Luca; Tulleken, Cornelius A F; Al-Mefty, Ossama

    2010-11-01

    Resident duty-hours restrictions have now been instituted in many countries worldwide. Shortened training times and increased public scrutiny of surgical competency have led to a move away from the traditional apprenticeship model of training. The development of educational models for brain anatomy is a fascinating innovation allowing neurosurgeons to train without the need to practice on real patients and it may be a solution to achieve competency within a shortened training period. The authors describe the use of Stratathane resin ST-504 polymer (SRSP), which is inserted at different intracranial locations to closely mimic meningiomas and other pathological entities of the skull base, in a cadaveric model, for use in neurosurgical training. Silicone-injected and pressurized cadaveric heads were used for studying the SRSP model. The SRSP presents unique intrinsic metamorphic characteristics: liquid at first, it expands and foams when injected into the desired area of the brain, forming a solid tumorlike structure. The authors injected SRSP via different passages that did not influence routes used for the surgical approach for resection of the simulated lesion. For example, SRSP injection routes included endonasal transsphenoidal or transoral approaches if lesions were to be removed through standard skull base approach, or, alternatively, SRSP was injected via a cranial approach if the removal was planned to be via the transsphenoidal or transoral route. The model was set in place in 3 countries (US, Italy, and The Netherlands), and a pool of 13 physicians from 4 different institutions (all surgeons and surgeons in training) participated in evaluating it and provided feedback. All 13 evaluating physicians had overall positive impressions of the model. The overall score on 9 components evaluated--including comparison between the tumor model and real tumor cases, perioperative requirements, general impression, and applicability--was 88% (100% being the best possible

  4. Symmetrical lividity of the palms and soles.

    Science.gov (United States)

    Rietschel, R L; Carr, J F; Lewis, C W

    1978-11-01

    Symmetrical lividity (SL) was the term coined by Pernet in 1925 for symmetrical, bluish-red plaques on the soles of the feet, accompanied by hyperhidrosis and not corresponding to areas of pressure or patterns of innervation. We report two patients with a persistent eruption of the palms analogous to that described by Pernet on the feet. Unlike most reported cases of SL, our patients did not respond to topical drying treatments, but one patient partially responded to tretinoin. There appear to be two forms of SL: transient, which responds to drying; and persistent which does not respond to drying. The hyperhidrosis studied in one of our two patients was significantly greater within the plaques of SL than the normal palm. While we could suppress the hyperhidrosis with topical therapy, this failed to clear his hyperkeratosis or eliminate the livid color.

  5. Model Based Definition

    Science.gov (United States)

    Rowe, Sidney E.

    2010-01-01

    In September 2007, the Engineering Directorate at the Marshall Space Flight Center (MSFC) created the Design System Focus Team (DSFT). MSFC was responsible for the in-house design and development of the Ares 1 Upper Stage and the Engineering Directorate was preparing to deploy a new electronic Configuration Management and Data Management System with the Design Data Management System (DDMS) based upon a Commercial Off The Shelf (COTS) Product Data Management (PDM) System. The DSFT was to establish standardized CAD practices and a new data life cycle for design data. Of special interest here, the design teams were to implement Model Based Definition (MBD) in support of the Upper Stage manufacturing contract. It is noted that this MBD does use partially dimensioned drawings for auxiliary information to the model. The design data lifecycle implemented several new release states to be used prior to formal release that allowed the models to move through a flow of progressive maturity. The DSFT identified some 17 Lessons Learned as outcomes of the standards development, pathfinder deployments and initial application to the Upper Stage design completion. Some of the high value examples are reviewed.

  6. 25 CFR 140.1 - Sole power to appoint.

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Sole power to appoint. 140.1 Section 140.1 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR FINANCIAL ACTIVITIES LICENSED INDIAN TRADERS § 140.1 Sole power to appoint. The Commissioner of Indian Affairs shall have the sole power and authority to...

  7. 40 CFR 1042.620 - Engines used solely for competition.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Engines used solely for competition... Special Compliance Provisions § 1042.620 Engines used solely for competition. The provisions of this... it is to be used solely for competition. The requirements of this part, other than those in this...

  8. 48 CFR 219.808-1 - Sole source.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Sole source. 219.808-1 Section 219.808-1 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM... Administration (The 8(a) Program) 219.808-1 Sole source. For sole source requirements processed under the PA...

  9. EPA Region 6 Sole Source Aquifers in Louisiana, Geographic NAD83, EPA (1996) [sole_source_aquifers_LA_EPA_1996

    Data.gov (United States)

    Louisiana Geographic Information Center — Polygon layer of EPA Region 6 sole source aquifers in Louisiana. The sole source aquifers represented are Chicot and Southern Hills in Louisiana/Mississippi.

  10. `Models of' versus `Models for'. Toward an Agent-Based Conception of Modeling in the Science Classroom

    Science.gov (United States)

    Gouvea, Julia; Passmore, Cynthia

    2017-03-01

    The inclusion of the practice of "developing and using models" in the Framework for K-12 Science Education and in the Next Generation Science Standards provides an opportunity for educators to examine the role this practice plays in science and how it can be leveraged in a science classroom. Drawing on conceptions of models in the philosophy of science, we bring forward an agent-based account of models and discuss the implications of this view for enacting modeling in science classrooms. Models, according to this account, can only be understood with respect to the aims and intentions of a cognitive agent (models for), not solely in terms of how they represent phenomena in the world (models of). We present this contrast as a heuristic— models of versus models for—that can be used to help educators notice and interpret how models are positioned in standards, curriculum, and classrooms.

  11. Evidence-based guidelines of the spanish psoriasis group on the use of biologic therapy in patients with psoriasis in difficult-to-treat sites (nails, scalp, palms, and soles).

    Science.gov (United States)

    Sánchez-Regaña, M; Aldunce Soto, M J; Belinchón Romero, I; Ribera Pibernat, M; Lafuente-Urrez, R F; Carrascosa Carrillo, J M; Ferrándiz Foraster, C; Puig Sanz, L; Daudén Tello, E; Vidal Sarró, D; Ruiz-Villaverde, R; Fonseca Capdevila, E; Rodríguez Cerdeira, M C; Alsina Gibert, M M; Herrera Acosta, E; Marrón Moya, S E

    2014-12-01

    Psoriatic lesions affecting the scalp, nails, palms, and the soles of the feet are described as difficult-to-treat psoriasis and require specific management. Involvement of these sites often has a significant physical and emotional impact on the patient and the lesions are difficult to control with topical treatments owing to inadequate penetration of active ingredients and the poor cosmetic characteristics of the vehicles used. Consequently, when difficult-to-treat sites are involved, psoriasis can be considered severe even though the lesions are not extensive. Scant information is available about the use of biologic therapy in this setting, and published data generally comes from clinical trials of patients who also had moderate to severe extensive lesions or from small case series and isolated case reports. In this article we review the quality of the scientific evidence for the 4 biologic agents currently available in Spain (infliximab, etanercept, adalimumab, and ustekinumab) and report level i evidence for the use of biologics to treat nail psoriasis (level of recommendation A) and a somewhat lower level of evidence in the case of scalp involvement and palmoplantar psoriasis. Copyright © 2013 Elsevier España, S.L.U. y AEDV. All rights reserved.

  12. Event-Based Conceptual Modeling

    DEFF Research Database (Denmark)

    Bækgaard, Lars

    The paper demonstrates that a wide variety of event-based modeling approaches are based on special cases of the same general event concept, and that the general event concept can be used to unify the otherwise unrelated fields of information modeling and process modeling. A set of event-based mod......The paper demonstrates that a wide variety of event-based modeling approaches are based on special cases of the same general event concept, and that the general event concept can be used to unify the otherwise unrelated fields of information modeling and process modeling. A set of event......-based modeling approaches are analyzed and the results are used to formulate a general event concept that can be used for unifying the seemingly unrelated event concepts. Events are characterized as short-duration processes that have participants, consequences, and properties, and that may be modeled in terms...

  13. Model-based Software Engineering

    DEFF Research Database (Denmark)

    Kindler, Ekkart

    2010-01-01

    The vision of model-based software engineering is to make models the main focus of software development and to automatically generate software from these models. Part of that idea works already today. But, there are still difficulties when it comes to behaviour. Actually, there is no lack in models...

  14. Principles of models based engineering

    Energy Technology Data Exchange (ETDEWEB)

    Dolin, R.M.; Hefele, J.

    1996-11-01

    This report describes a Models Based Engineering (MBE) philosophy and implementation strategy that has been developed at Los Alamos National Laboratory`s Center for Advanced Engineering Technology. A major theme in this discussion is that models based engineering is an information management technology enabling the development of information driven engineering. Unlike other information management technologies, models based engineering encompasses the breadth of engineering information, from design intent through product definition to consumer application.

  15. Structural evolution of the Semail Ophiolite metamorphic sole, Wadi Hawasina and Northern Jebel Nakhl Culmination, Oman

    Science.gov (United States)

    Hurtado, C.; Bailey, C.; Visokay, L.; Scharf, A.

    2017-12-01

    The Semail ophiolite is the world's largest and best-exposed ophiolite sequence, however the processes associated with both oceanic detachment and later emplacement onto the Arabian continental margin remain enigmatic. This study examines the upper mantle section of the ophiolite, its associated metamorphic sole, and the autochthonous strata beneath the ophiolite at two locations in northern Oman. Our purpose is to understand the structural history of ophiolite emplacement and evaluate the deformation kinematics of faulted and sheared rocks in the metamorphic sole. At Wadi Hawasina, the base of the ophiolite is defined by a 5- to 15-m thick zone of penetratively-serpentinized mylonitic peridotite. Kinematic indicators record top-to-the SW (reverse) sense-of-shear with a triclinic deformation asymmetry. An inverted metamorphic grade is preserved in the 300- to 500-m thick metamorphic sole that is thrust over deep-water sedimentary rocks of the Hawasina Group. The study site near Buwah, in the northern Jebel Nakhl culmination, contains a N-to-S progression of mantle peridotite, metamorphic sole, and underlying Jurassic carbonates. Liswanite crops out in NW-SE trending linear ridges in the peridotite. The metamorphic sole includes well-foliated quartzite, metachert, and amphibolite. Kinematic evidence indicates that the liswanite and a serpentinized mélange experienced top to-the north (normal) sense-of-shear. Two generations of E-W striking, N-dipping normal faults separate the autochthonous sequence from the metamorphic sole, and also cut out significant sections of the metamorphic sole. Fabric analysis reveals that the metamorphic sole experienced flattening strain (K<0.2) that accumulated during pure shear-dominated general shear (Wk<0.4). Normal faulting and extension at the Buwah site indicates that post-ophiolite deformation is significant in the Jebel Akhdar and Jebel Nakhl culminations.

  16. Discards monitoring in the gillnet fishery for sole

    NARCIS (Netherlands)

    Uhlmann, S.S.

    2014-01-01

    Approximately 2-3% of the Dutch fishing quota for sole (Solea solea) is caught by a 60-vessel strong inshore fleet of gillnetters. From their home ports in IJmuiden, Scheveningen and Den Helder, these vessels fish typically with bottom-set gillnets for sole during 1 day trips between March and

  17. 40 CFR 721.2380 - Disubstituted diamino ani-sole.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Disubstituted diamino ani-sole. 721.2380 Section 721.2380 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC... Substances § 721.2380 Disubstituted diamino ani-sole. (a) Chemical substance and significant new uses subject...

  18. 31 CFR 515.546 - Accounts of Cuban sole proprietorships.

    Science.gov (United States)

    2010-07-01

    ... proprietorships. Specific licenses are issued unblocking sole proprietorships established under the laws of Cuba... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Accounts of Cuban sole proprietorships. 515.546 Section 515.546 Money and Finance: Treasury Regulations Relating to Money and Finance...

  19. 48 CFR 19.811-1 - Sole source.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Sole source. 19.811-1 Section 19.811-1 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC....811-1 Sole source. (a) The contract to be awarded by the agency to the SBA shall be prepared in...

  20. Cluster Based Text Classification Model

    DEFF Research Database (Denmark)

    Nizamani, Sarwat; Memon, Nasrullah; Wiil, Uffe Kock

    2011-01-01

    We propose a cluster based classification model for suspicious email detection and other text classification tasks. The text classification tasks comprise many training examples that require a complex classification model. Using clusters for classification makes the model simpler and increases......, the classifier is trained on each cluster having reduced dimensionality and less number of examples. The experimental results show that the proposed model outperforms the existing classification models for the task of suspicious email detection and topic categorization on the Reuters-21578 and 20 Newsgroups...... datasets. Our model also outperforms A Decision Cluster Classification (ADCC) and the Decision Cluster Forest Classification (DCFC) models on the Reuters-21578 dataset....

  1. Graph Model Based Indoor Tracking

    DEFF Research Database (Denmark)

    Jensen, Christian Søndergaard; Lu, Hua; Yang, Bin

    2009-01-01

    The tracking of the locations of moving objects in large indoor spaces is important, as it enables a range of applications related to, e.g., security and indoor navigation and guidance. This paper presents a graph model based approach to indoor tracking that offers a uniform data management...... infrastructure for different symbolic positioning technologies, e.g., Bluetooth and RFID. More specifically, the paper proposes a model of indoor space that comprises a base graph and mappings that represent the topology of indoor space at different levels. The resulting model can be used for one or several...... indoor positioning technologies. Focusing on RFID-based positioning, an RFID specific reader deployment graph model is built from the base graph model. This model is then used in several algorithms for constructing and refining trajectories from raw RFID readings. Empirical studies with implementations...

  2. Association of digital cushion thickness with sole temperature measured with the use of infrared thermography.

    Science.gov (United States)

    Oikonomou, G; Trojacanec, P; Ganda, E K; Bicalho, M L S; Bicalho, R C

    2014-07-01

    The main objective of this study was to investigate the association between digital cushion thickness and sole temperature measured by infrared thermography. Data were collected from 216 lactating Holstein cows at 4 to 10d in milk (DIM). Cows were locomotion scored and sole temperature was measured after claw trimming (a minimum delay of 3 min was allowed for the hoof to cool) using an infrared thermography camera. Temperature was measured at the typical ulcer site of the lateral digit of the left hind foot. Immediately after the thermographic image was obtained, the thickness of the digital cushion was measured by ultrasonography. Rumen fluid samples were collected with a stomach tube and sample pH was measured immediately after collection. Additionally, a blood sample was obtained and used for measurements of serum concentrations of β-hydroxybutyrate (BHBA), nonesterified fatty acids (NEFA), and haptoglobin. To evaluate the associations of digital cushion thickness with sole temperature, a linear regression model was built using the GLIMMIX procedure in SAS software (SAS Institute Inc., Cary, NC). Sole temperature was the response variable, and digital cushion thickness quartiles, locomotion score group, rumen fluid pH, rumen fluid sample volume, environmental temperature, age in days, and serum levels of NEFA, BHBA, and haptoglobin were fitted in the model. Only significant variables were retained in the final model. Simple linear regression scatter plots were used to illustrate associations between sole temperature (measured by infrared thermography at the typical ulcer site) and environmental temperature and between NEFA and BHBA serum levels and haptoglobin. One-way ANOVA was used to compare rumen fluid pH for different locomotion score groups and for different digital cushion quartiles. Results from the multivariable linear regression model showed that sole temperature increased as locomotion scores increased and decreased as digital cushion thickness

  3. Activity-based DEVS modeling

    DEFF Research Database (Denmark)

    Alshareef, Abdurrahman; Sarjoughian, Hessam S.; Zarrin, Bahram

    2018-01-01

    architecture and the UML concepts. In this paper, we further this work by grounding Activity-based DEVS modeling and developing a fully-fledged modeling engine to demonstrate applicability. We also detail the relevant aspects of the created metamodel in terms of modeling and simulation. A significant number...

  4. KINETIC ASSESSMENT OF GOLF SHOE OUTER SOLE DESIGN FEATURES

    Directory of Open Access Journals (Sweden)

    Rosemary J. Dyson

    2009-12-01

    Full Text Available This study assessed human kinetics in relation to golf shoe outer sole design features during the golf swing using a driver club by measuring both within the shoe, and beneath the shoe at the natural grass interface. Three different shoes were assessed: metal 7- spike shoe, alternative 7-spike shoe, and a flat soled shoe. In-shoe plantar pressure data were recorded using Footscan RS International pressure insoles and sampling at 500 Hz. Simultaneously ground reaction force at the shoe outer sole was measured using 2 natural grass covered Kistler force platforms and 1000 Hz data acquisition. Video recording of the 18 right-handed golfers at 200 Hz was undertaken while the golfer performed 5 golf shots with his own driver in each type of shoe. Front foot (nearest to shot direction maximum vertical force and torque were greater than at the back foot, and there was no significant difference related to the shoe type. Wearing the metal spike shoe when using a driver was associated with more torque generation at the back foot (p < 0. 05 than when the flat soled shoe was worn. Within shoe regional pressures differed significantly with golf shoe outer sole design features (p < 0.05. Comparison of the metal spike and alternative spike shoe results provided indications of the quality of regional traction on the outer sole. Potential golf shoe outer sole design features and traction were presented in relation to phases of the golf swing movement. Application of two kinetic measurement methods identified that moderated (adapted muscular control of foot and body movement may be induced by golf shoe outer sole design features. Ground reaction force measures inform comparisons of overall shoe functional performance, and insole pressure measurements inform comparisons of the underfoot conditions induced by specific regions of the golf shoe outer sole

  5. Symmetric lividity of the soles as seen in private practice.

    Science.gov (United States)

    NELSON, L M

    1956-10-01

    As seen in private practice, symmetric lividity of the soles is a relatively common condition which occurs predominantly in males in the first three decades of life.Untreated, the syndrome may persist for many years or it may be self-limiting, lasting only a few days. Occupation does not seem to be a factor predisposing to symmetric lividity of the soles. There is a high incidence of family occurrence of this condition.Any form of treatment which controls the hyperhidrosis controls the other symptoms of symmetric lividity of the soles.

  6. Mars 2020 Model Based Systems Engineering Pilot

    Science.gov (United States)

    Dukes, Alexandra Marie

    2017-01-01

    The pilot study is led by the Integration Engineering group in NASA's Launch Services Program (LSP). The Integration Engineering (IE) group is responsible for managing the interfaces between the spacecraft and launch vehicle. This pilot investigates the utility of Model-Based Systems Engineering (MBSE) with respect to managing and verifying interface requirements. The main objectives of the pilot are to model several key aspects of the Mars 2020 integrated operations and interface requirements based on the design and verification artifacts from Mars Science Laboratory (MSL) and to demonstrate how MBSE could be used by LSP to gain further insight on the interface between the spacecraft and launch vehicle as well as to enhance how LSP manages the launch service. The method used to accomplish this pilot started through familiarization of SysML, MagicDraw, and the Mars 2020 and MSL systems through books, tutorials, and NASA documentation. MSL was chosen as the focus of the model since its processes and verifications translate easily to the Mars 2020 mission. The study was further focused by modeling specialized systems and processes within MSL in order to demonstrate the utility of MBSE for the rest of the mission. The systems chosen were the In-Flight Disconnect (IFD) system and the Mass Properties process. The IFD was chosen as a system of focus since it is an interface between the spacecraft and launch vehicle which can demonstrate the usefulness of MBSE from a system perspective. The Mass Properties process was chosen as a process of focus since the verifications for mass properties occur throughout the lifecycle and can demonstrate the usefulness of MBSE from a multi-discipline perspective. Several iterations of both perspectives have been modeled and evaluated. While the pilot study will continue for another 2 weeks, pros and cons of using MBSE for LSP IE have been identified. A pro of using MBSE includes an integrated view of the disciplines, requirements, and

  7. Sole Source Aquifers, Region 9, 2008, US EPA Region 9

    Data.gov (United States)

    U.S. Environmental Protection Agency — There are 7 polygons representing 6 individual sole source aquifer boundaries and one streamflow source area in California, Arizona, and Nevada. Various efforts were...

  8. Event-Based Conceptual Modeling

    DEFF Research Database (Denmark)

    Bækgaard, Lars

    2009-01-01

    The purpose of the paper is to obtain insight into and provide practical advice for event-based conceptual modeling. We analyze a set of event concepts and use the results to formulate a conceptual event model that is used to identify guidelines for creation of dynamic process models and static...... information models. We characterize events as short-duration processes that have participants, consequences, and properties, and that may be modeled in terms of information structures. The conceptual event model is used to characterize a variety of event concepts and it is used to illustrate how events can...... be used to integrate dynamic modeling of processes and static modeling of information structures. The results are unique in the sense that no other general event concept has been used to unify a similar broad variety of seemingly incompatible event concepts. The general event concept can be used...

  9. Barriers to Maori sole mothers’ primary health care access

    Directory of Open Access Journals (Sweden)

    Lee R

    2013-12-01

    Full Text Available INTRODUCTION: International research consistently shows that sole mothers experience poorer health and suboptimal health care access. New Zealand studies on sole mothers' health report similar findings. The aim of this exploratory research was to better understand the experiences of Maori sole mothers' access to health services, particularly primary health care, for personal health needs. METHODS: This qualitative study employed a general inductive design informed by a Kaupapa Maori approach, providing guidance on appropriate cultural protocols for recruiting and engaging Maori participants. Distributing written information and snowballing techniques were used to purposively recruit seven Maori sole mothers. Data collection involved semi-structured interviews which were digitally recorded and transcribed verbatim. Data were analysed using general inductive thematic analysis to identify commonalities and patterns in participants' experiences. FINDINGS: The dominant themes that emerged captured and described participants' experiences in accessing health care. The major barrier to access reported was cost. Compounding cost, transport difficulties and location or scheduling of services were additional barriers to health service accessibility. Child-related issues also posed a barrier, including prioritising children's needs and childcare over personal health needs. CONCLUSION: The findings illuminate Maori sole mothers' experiences of accessing health care and the complex socioeconomic inequalities affecting access options and uptake of services. Further investigation of barriers to access is needed. The study has implications for addressing barriers to access at policy, funding and practice levels to improve health outcomes and equitable health care access for Maori sole mothers.

  10. Event-Based Activity Modeling

    DEFF Research Database (Denmark)

    Bækgaard, Lars

    2004-01-01

    We present and discuss a modeling approach that supports event-based modeling of information and activity in information systems. Interacting human actors and IT-actors may carry out such activity. We use events to create meaningful relations between information structures and the related...

  11. Model-based biosignal interpretation.

    Science.gov (United States)

    Andreassen, S

    1994-03-01

    Two relatively new approaches to model-based biosignal interpretation, qualitative simulation and modelling by causal probabilistic networks, are compared to modelling by differential equations. A major problem in applying a model to an individual patient is the estimation of the parameters. The available observations are unlikely to allow a proper estimation of the parameters, and even if they do, the task appears to have exponential computational complexity if the model is non-linear. Causal probabilistic networks have both differential equation models and qualitative simulation as special cases, and they can provide both Bayesian and maximum-likelihood parameter estimates, in most cases in much less than exponential time. In addition, they can calculate the probabilities required for a decision-theoretical approach to medical decision support. The practical applicability of causal probabilistic networks to real medical problems is illustrated by a model of glucose metabolism which is used to adjust insulin therapy in type I diabetic patients.

  12. Introducing a model of pairing based on base pair specific interactions between identical DNA sequences

    Science.gov (United States)

    (O’ Lee, Dominic J.

    2018-02-01

    At present, there have been suggested two types of physical mechanism that may facilitate preferential pairing between DNA molecules, with identical or similar base pair texts, without separation of base pairs. One mechanism solely relies on base pair specific patterns of helix distortion being the same on the two molecules, discussed extensively in the past. The other mechanism proposes that there are preferential interactions between base pairs of the same composition. We introduce a model, built on this second mechanism, where both thermal stretching and twisting fluctuations are included, as well as the base pair specific helix distortions. Firstly, we consider an approximation for weak pairing interactions, or short molecules. This yields a dependence of the energy on the square root of the molecular length, which could explain recent experimental data. However, analysis suggests that this approximation is no longer valid at large DNA lengths. In a second approximation, for long molecules, we define two adaptation lengths for twisting and stretching, over which the pairing interaction can limit the accumulation of helix disorder. When the pairing interaction is sufficiently strong, both adaptation lengths are finite; however, as we reduce pairing strength, the stretching adaptation length remains finite but the torsional one becomes infinite. This second state persists to arbitrarily weak values of the pairing strength; suggesting that, if the molecules are long enough, the pairing energy scales as length. To probe differences between the two pairing mechanisms, we also construct a model of similar form. However, now, pairing between identical sequences solely relies on the intrinsic helix distortion patterns. Between the two models, we see interesting qualitative differences. We discuss our findings, and suggest new work to distinguish between the two mechanisms.

  13. Electrohydrodynamic flow caused by field-enhanced dissociation solely

    Science.gov (United States)

    Vasilkov, S. A.; Chirkov, V. A.; Stishkov, Yu. K.

    2017-06-01

    Electrohydrodynamic (EHD) flows emerge in dielectric liquids under the action of the Coulomb force and underlie energy-efficient techniques for heat and mass transfer. The key issue in the phenomena is the way how the net charge is created. One of the most promising, yet poorly studied charge formation mechanisms is the field-enhanced dissociation (or the Wien effect). So the paper studies an EHD flow caused solely by the effect by virtue of both experiment and computer simulation. To preclude the competing mechanism of charge formation—the injection—a new EHD system of a special design was examined. Its main feature is the use of solid insulation to create the region of the strong electric field far from the electrode metal surfaces. The experimental study used the particle image velocimetry technique to observe velocity distributions, whereas the computations were based on the complete set of electrohydrodynamic equations employing the commercial software package COMSOL Multiphysics. Spatial distributions of key quantities (including the ion concentrations, the total space charge density, and the velocity) and the acting forces were obtained in the computer simulation and were analyzed. The experimental flow structure was observed for a number of voltages up to 30 kV. The comparison of the numerical and experimental results yielded a good quantitative agreement for strong electric fields though some overshoot was observed for weak ones. The results allow concluding on the applicability of the Onsager theory of the field-enhanced dissociation in the context of EHD flows.

  14. Model-based machine learning.

    Science.gov (United States)

    Bishop, Christopher M

    2013-02-13

    Several decades of research in the field of machine learning have resulted in a multitude of different algorithms for solving a broad range of problems. To tackle a new application, a researcher typically tries to map their problem onto one of these existing methods, often influenced by their familiarity with specific algorithms and by the availability of corresponding software implementations. In this study, we describe an alternative methodology for applying machine learning, in which a bespoke solution is formulated for each new application. The solution is expressed through a compact modelling language, and the corresponding custom machine learning code is then generated automatically. This model-based approach offers several major advantages, including the opportunity to create highly tailored models for specific scenarios, as well as rapid prototyping and comparison of a range of alternative models. Furthermore, newcomers to the field of machine learning do not have to learn about the huge range of traditional methods, but instead can focus their attention on understanding a single modelling environment. In this study, we show how probabilistic graphical models, coupled with efficient inference algorithms, provide a very flexible foundation for model-based machine learning, and we outline a large-scale commercial application of this framework involving tens of millions of users. We also describe the concept of probabilistic programming as a powerful software environment for model-based machine learning, and we discuss a specific probabilistic programming language called Infer.NET, which has been widely used in practical applications.

  15. Stiffness Effects in Rocker-Soled Shoes: Biomechanical Implications.

    Directory of Open Access Journals (Sweden)

    Shih-Yun Lin

    Full Text Available Rocker-soled shoes provide a way to reduce the possible concentration of stress, as well as change movement patterns, during gait. This study attempts to examine how plantar force and spatio-temporal variables are affected by two rocker designs, one with softer and one with denser sole materials, by comparing them with the barefoot condition and with flat-soled shoes. Eleven subjects' gait parameters during walking and jogging were recorded. Our results showed that compared with barefoot walking, plantar forces were higher for flat shoes while lower for both types of rocker shoes, the softer-material rocker being the lowest. The plantar force of flat shoes is greater than the vertical ground reaction force, while that of both rocker shoes is much less, 13.87-30.55% body weight. However, as locomotion speed increased to jogging, for all shoe types, except at the second peak plantar force of the denser sole material rocker shoes, plantar forces were greater than for bare feet. More interestingly, because the transmission of force was faster while jogging, greater plantar force was seen in the rocker-soled shoes with softer material than with denser material; results for higher-speed shock absorption in rocker-soled shoes with softer material were thus not as good. In general, the rolling phenomena along the bottom surface of the rocker shoes, as well as an increase in the duration of simultaneous curve rolling and ankle rotation, could contribute to the reduction of plantar force for both rocker designs. The possible mechanism is the conversion of vertical kinetic energy into rotational kinetic energy. To conclude, since plantar force is related to foot-ground interface and deceleration methods, rocker-design shoes could achieve desired plantar force reduction through certain rolling phenomena, shoe-sole stiffness levels, and locomotion speeds.

  16. Stiffness Effects in Rocker-Soled Shoes: Biomechanical Implications.

    Science.gov (United States)

    Lin, Shih-Yun; Su, Pei-Fang; Chung, Chia-Hua; Hsia, Chi-Chun; Chang, Chih-Han

    2017-01-01

    Rocker-soled shoes provide a way to reduce the possible concentration of stress, as well as change movement patterns, during gait. This study attempts to examine how plantar force and spatio-temporal variables are affected by two rocker designs, one with softer and one with denser sole materials, by comparing them with the barefoot condition and with flat-soled shoes. Eleven subjects' gait parameters during walking and jogging were recorded. Our results showed that compared with barefoot walking, plantar forces were higher for flat shoes while lower for both types of rocker shoes, the softer-material rocker being the lowest. The plantar force of flat shoes is greater than the vertical ground reaction force, while that of both rocker shoes is much less, 13.87-30.55% body weight. However, as locomotion speed increased to jogging, for all shoe types, except at the second peak plantar force of the denser sole material rocker shoes, plantar forces were greater than for bare feet. More interestingly, because the transmission of force was faster while jogging, greater plantar force was seen in the rocker-soled shoes with softer material than with denser material; results for higher-speed shock absorption in rocker-soled shoes with softer material were thus not as good. In general, the rolling phenomena along the bottom surface of the rocker shoes, as well as an increase in the duration of simultaneous curve rolling and ankle rotation, could contribute to the reduction of plantar force for both rocker designs. The possible mechanism is the conversion of vertical kinetic energy into rotational kinetic energy. To conclude, since plantar force is related to foot-ground interface and deceleration methods, rocker-design shoes could achieve desired plantar force reduction through certain rolling phenomena, shoe-sole stiffness levels, and locomotion speeds.

  17. Stiffness Effects in Rocker-Soled Shoes: Biomechanical Implications

    Science.gov (United States)

    Su, Pei-Fang; Chung, Chia-Hua; Hsia, Chi-Chun; Chang, Chih-Han

    2017-01-01

    Rocker-soled shoes provide a way to reduce the possible concentration of stress, as well as change movement patterns, during gait. This study attempts to examine how plantar force and spatio-temporal variables are affected by two rocker designs, one with softer and one with denser sole materials, by comparing them with the barefoot condition and with flat-soled shoes. Eleven subjects’ gait parameters during walking and jogging were recorded. Our results showed that compared with barefoot walking, plantar forces were higher for flat shoes while lower for both types of rocker shoes, the softer-material rocker being the lowest. The plantar force of flat shoes is greater than the vertical ground reaction force, while that of both rocker shoes is much less, 13.87–30.55% body weight. However, as locomotion speed increased to jogging, for all shoe types, except at the second peak plantar force of the denser sole material rocker shoes, plantar forces were greater than for bare feet. More interestingly, because the transmission of force was faster while jogging, greater plantar force was seen in the rocker-soled shoes with softer material than with denser material; results for higher-speed shock absorption in rocker-soled shoes with softer material were thus not as good. In general, the rolling phenomena along the bottom surface of the rocker shoes, as well as an increase in the duration of simultaneous curve rolling and ankle rotation, could contribute to the reduction of plantar force for both rocker designs. The possible mechanism is the conversion of vertical kinetic energy into rotational kinetic energy. To conclude, since plantar force is related to foot-ground interface and deceleration methods, rocker-design shoes could achieve desired plantar force reduction through certain rolling phenomena, shoe-sole stiffness levels, and locomotion speeds. PMID:28046009

  18. Differences in sole arch indices in various sports.

    Science.gov (United States)

    Aydog, S T; Tetik, O; Demirel, H A; Doral, M N

    2005-02-01

    There are controversial data about the relation between foot morphology and athletic injuries of the lower extremity. Studies in soldiers have shown some relationship, whereas those involving athletes have not shown any significant relationship. The reason for these differences is not clear. To determine the effect of various sports on sole arch indices (AIs). A total of 116 elite male athletes (24 soccer players, 23 wrestlers, 19 weightlifters, 30 handball players, and 20 gymnasts) and 30 non-athletic men were included in this cross sectional study. Images of both soles were taken in a podoscope and transferred to a computer using a digital still camera. AIs were calculated from the stored images. The AI of the right sole of the gymnasts was significantly lower than that of the soccer players, wrestlers, and non-athletic controls (pAI of the right sole of the wrestlers was significantly higher than that of the soccer players, handball players, weightlifters, gymnasts, and non-athletic controls (pAI of the left sole of the gymnasts was significantly lower than that of the wrestlers and non-athletic controls (pAI of the left sole of the wrestlers was significantly higher than that of the soccer players, handball players, and gymnasts (pAI of both soles in handball players was significantly lower than those of the non-athletic subjects (p = 0.049). The correlation between the AI of the left and right foot was poor in the soccer players, handball players, and wrestlers (r = 0.31, 0.69, and 0.56 respectively), but was high in the gymnasts, weightlifters, and non-athletic controls (r = 0.96, 0.88, and 0.80 respectively). The AIs of the gymnasts and wrestlers were significantly different from those of other sportsmen studied, and those of the gymnasts and handball players were significantly different from those of non-athletic controls.

  19. Computer-Based Modeling Environments

    Science.gov (United States)

    1989-01-01

    1988). "An introduction to graph-based modeling Rich. E. (1983). Artificial Inteligence , McGraw-Hill, New York. systems", Working Paper 88-10-2...Hall, J., S. Lippman, and J. McCall. "Expected Utility Maximizing Job Search," Chapter 7 of Studies in the Economics of Search, 1979, North-Holland. WMSI...The same shape has been used theory, as knowledge representation in artificial for data sources and analytical models because, at intelligence, and as

  20. Pathogenesis and Treatment of Sole Ulcers and White Line Disease.

    Science.gov (United States)

    Shearer, J K; van Amstel, Sarel R

    2017-07-01

    Sole ulcers and white line disease are 2 of the most common claw horn lesions in confined dairy cattle. Predisposing causes include unbalanced weight bearing, and metabolic, enzymatic, and hormonal changes. The white line serves as the junction between the sole and axial and abaxial wall. It is vulnerable to trauma and separation, permitting organic matter to become entrapped. Colonization contributes to retrograde movement of the infection to the solar and perioplic corium, where an abscess forms resulting in pain and lameness. Successful treatment requires an orthopedic foot block to the healthy claw and corrective trimming of the lesion. Copyright © 2017 Elsevier Inc. All rights reserved.

  1. Phosphoenolpyruvate Carboxykinase as the Sole Anaplerotic Enzyme in Saccharomyces cerevisiae

    NARCIS (Netherlands)

    Zelle, R.M.; Trueheart, J.; Harrison, J.C.; Pronk, J.T.; Van Maris, A.J.A.

    2010-01-01

    Pyruvate carboxylase is the sole anaplerotic enzyme in glucose-grown cultures of wild-type Saccharomyces cerevisiae. Pyruvate carboxylase-negative (Pyc–) S. cerevisiae strains cannot grow on glucose unless media are supplemented with C4 compounds, such as aspartic acid. In several

  2. Deaths among West African dwarf goats fed sole Dactyladaenia barteri

    African Journals Online (AJOL)

    Dactyladaema barteri is an important shrub utilized in fallow development and as a much-preferred ruminant browse by local farmers in Nigeria. We report the death of two 12 – 15 months old West African Dwarf (WAD) goats used in a digestibility trail with D. barteri as sole feed and in a mixed browse - grass diet in the ...

  3. pigmentation of the sole of the foot in rhodesian africans

    African Journals Online (AJOL)

    1971-01-23

    Jan 23, 1971 ... (Photo by courtesy of Dr C. M. D. Ross.) Fig. 8. From a biopsy of a grade III area on the sole of the foot a section shows, apart from proliferated melanocytes in the basal layer, isolated pigmented cells extending through the stratum malpighii to the stratum granulosum above it, (Photo by courtesy of Dr C.

  4. ELECTROCHEMICAL TECHNOLOGIES FOR OBTAINING MOULDS FOR SOLES OF SHOES

    Directory of Open Access Journals (Sweden)

    Cornelia LUCA

    2013-05-01

    Full Text Available The paper presents contributions in the designing of some electrochemical technologiesfor the manufacturing of the moulds used in the footwear soles obtaining. There are presented a fewmethods for the moulds obtaining, using electro-deposit processes. There are presented thetechnological phases of the obtaining process of the electrolytes and electrodes preparing and thetechnological stages of the moulds manufacturing.

  5. Degloved foot sole successfully reconstructed with split thickness skin grafts

    NARCIS (Netherlands)

    Janssens, Loes; Holtslag, Herman R.; Schellekens, Pascal P A; Leenen, Luke P H

    2015-01-01

    Introduction The current opinion is that split thickness skin grafts are not suitable to reconstruct a degloved foot sole. The tissue is too fragile to carry full bodyweight; and therefore, stress lesions frequently occur. The treatment of choice is the reuse of the avulsed skin whenever possible,

  6. 48 CFR 619.811-1 - Sole source.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Sole source. 619.811-1 Section 619.811-1 Federal Acquisition Regulations System DEPARTMENT OF STATE SOCIOECONOMIC PROGRAMS SMALL... source. (d) If the award is to be made under an MOU cited in 619.800, the contract to be awarded by the...

  7. 48 CFR 619.808-1 - Sole source.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Sole source. 619.808-1... source. (a) If the acquisition is conducted under an MOU cited in 619.800, the 8(a) contractor is... may, after notification and approval by SBA, proceed with the acquisition from other sources. (b) If...

  8. Recognition and Accountability: Sole Parent Postgraduates in University Conditions

    Science.gov (United States)

    Hook, Genine A.

    2015-01-01

    This paper aims to examine some of ways sole parents sought recognition as postgraduate students in Australian universities. Judith Butler's theory of recognition notes that recognition is always partial and any account we give of ourselves must be given to another. Participants articulated that supervisors were critical in the process of…

  9. 48 CFR 19.808-1 - Sole source.

    Science.gov (United States)

    2010-10-01

    ... PROGRAMS SMALL BUSINESS PROGRAMS Contracting With the Small Business Administration (the 8(a) Program) 19.808-1 Sole source. (a) The SBA is responsible for initiating negotiations with the agency within the time established by the agency. If the SBA does not initiate negotiations within the agreed time and...

  10. pigmentation of the sole of the foot in rhodesian africans

    African Journals Online (AJOL)

    1971-01-23

    Jan 23, 1971 ... basal layer. (Photo by courtesy of Dr C. M. D. Ross.) Fig. 8. From a biopsy of a grade III area on the sole of the foot a section shows, apart from proliferated melanocytes in the basal layer, isolated pigmented cells extending through the stratum malpighii to the stratum granulosum above it, (Photo by courtesy ...

  11. Yield Performance of Some Cowpea Varieties under Sole and ...

    African Journals Online (AJOL)

    Nekky Umera

    commodity call for a relatively cheaper alternative to fertilizer application, so as to increase crop production while at the same time improving the fertility of the soil. In view of the above, this research was undertaken in other to study the yield performance of some cowpea varieties and maize under sole and intercropping.

  12. Artificial gynogenesis and sex determination in half-smooth tongue sole (Cynoglossus semilaevis).

    Science.gov (United States)

    Chen, Song-Lin; Tian, Yong-Sheng; Yang, Jing-Feng; Shao, Chang-Wei; Ji, Xiang-Shan; Zhai, Jie-Ming; Liao, Xiao-Lin; Zhuang, Zhi-Meng; Su, Peng-Zhi; Xu, Jian-Yong; Sha, Zhen-Xia; Wu, Peng-Fei; Wang, Na

    2009-01-01

    Half-smooth tongue sole (Cynoglossus semilaevis) is an important cultured marine fish as well as a promising model fish for the study of sex determination mechanisms. In the present study, a protocol for artificial gynogenesis of half-smooth tongue sole was developed in order to identify the sex determination mechanism and to generate all-female stock. The optimal UV-irradiation dose for genetically inactivating sea perch spermatozoa was determined to be > or =30 mJ/cm(2). The optimal initiation time for cold shock of gynogenetic embryos was determined to be 5 min after fertilization, while the optimal temperature and treatment duration were determined to be 20-25 min at 5 degrees C. Chromosomes from common diploids, gynogenetic haploids, and diploids were analyzed. WW chromosomes were discovered in some of the gynogenetic diploids. The microsatellite marker was applied to analyze gynogenetic diploid fry. Among the 30 gynogenetic diploid fry, 11 fry contained only one allele, while 19 contained two alleles, which had the same genotype as their mother. The female-specific DNA marker was observed in four individuals out of ten gynogenetic diploid fry. Ploidy analysis of 20 putative gynogenetic fry showed them all to be diploid. Thus, a protocol for the induction of artificial gynogenesis has been developed for the first time in half smooth tongue sole, and the sex determination mechanism in the tongue sole was determined to be female heterogametic with the ZW chromosome.

  13. Shoe sole tread designs and outcomes of slipping and falling on slippery floor surfaces.

    Directory of Open Access Journals (Sweden)

    Li-Wen Liu

    Full Text Available A gait experiment was conducted under two shoe sole and three floor conditions. The shoe soles and floors were characterized by the tread and groove designs on the surface. The coefficients of friction (COF on the floor in the target area were measured. The subjects were required to walk on a walkway and stepping on a target area covered with glycerol. The motions of the feet of the subjects were captured. Gait parameters were calculated based on the motion data. Among the 240 trials, there were 37 no-slips, 81 microslips, 45 slides, and 77 slips. It was found that the condition with shoe sole and floor had both tread grooves perpendicular to the walking direction had the highest COF, the shortest slip distance, and the lowest percentages of slide and slip. The condition with shoe sole and floor had both tread grooves parallel to the walking direction had the lowest COF and the longest slip distance among all experimental conditions. The Pearson's correlation coefficients between slip distance and slip velocity, time to foot flat, foot angle, and compensatory step length were 0.82 (p<0.0001, 0.33 (p<0.0001, -0.54 (p<0.0001, and -0.51 (p<0.0001, respectively.

  14. Model-Based Security Testing

    Directory of Open Access Journals (Sweden)

    Ina Schieferdecker

    2012-02-01

    Full Text Available Security testing aims at validating software system requirements related to security properties like confidentiality, integrity, authentication, authorization, availability, and non-repudiation. Although security testing techniques are available for many years, there has been little approaches that allow for specification of test cases at a higher level of abstraction, for enabling guidance on test identification and specification as well as for automated test generation. Model-based security testing (MBST is a relatively new field and especially dedicated to the systematic and efficient specification and documentation of security test objectives, security test cases and test suites, as well as to their automated or semi-automated generation. In particular, the combination of security modelling and test generation approaches is still a challenge in research and of high interest for industrial applications. MBST includes e.g. security functional testing, model-based fuzzing, risk- and threat-oriented testing, and the usage of security test patterns. This paper provides a survey on MBST techniques and the related models as well as samples of new methods and tools that are under development in the European ITEA2-project DIAMONDS.

  15. Seasonal incidence of lameness and risk factors associated with thin soles, white line disease, ulcers, and sole punctures in dairy cattle.

    Science.gov (United States)

    Sanders, A H; Shearer, J K; De Vries, A

    2009-07-01

    Lameness is a multifactorial condition with many causes. In this study, cow lifetime records were used to quantify the incidence of specific lameness-causing lesions and investigate factors associated with those lesions. Of primary interest were the effects of seasonality and the effects of thin soles (TS). Thin sole-induced toe ulcers (TSTU) occurring adjacent to the white line in the apical portion of the weight-bearing surface were distinguished from white line disease (WLD) occurring in the region of the abaxial heel sole junction. Sole (SU), heel (HU), and toe (TU) ulcers; TS; sole punctures (SP); leg injuries (INJ); and other (OTH) lesions (e.g., infectious diseases, laminitis, unclassified hemorrhage) were also considered. Data were collected from May 2004 through October 2007 and included records for 4,915 cows of which 1,861 had at least one recorded lameness event. Of these, 20% were TSTU, 20% OTH, 16% SU, 13% TS, 10% WLD, 8% HU, 6% INJ, 4% SP, and 2% TU. Annual incidence risk for lameness was 49.1%. Overall incidence rate for lameness was 1.41/1,000 cow-days, and rates for all lesions were highest in the summer. As parity increased, so did incidence rates for TS, SU, WLD, HU, and INJ. For TS, TSTU, and WLD, incidence rates were lowest in early lactation (16 to 60 DIM), whereas for SU, HU, TU, incidence rates were highest in mid lactation (61 to 150 DIM). Cox proportional hazard models for TS, TSTU, WLD, SU, HU, TU, and SP included age and year of first calving and milk production capacity. Prior/concurrent lameness events, season, parity, and stage of lactation were included as time-dependent effects. Prior/concurrent TS increased the hazard for all other lesions, particularly TSTU, and HU. Having any other prior claw lesion also increased the hazard for all lesions. Hazard was highest in summer for all lesions except TU. Stage of lactation was a significant effect in hazard of TSTU, which was lowest in mid lactation (61 to 150 DIM).

  16. Spatial and temporal relations of the ophiolites and the metamorphic soles along the Tauride belt, Turkey

    Science.gov (United States)

    Parlak, Osman; Simsek, Emrah; Ezgi Ozturk, Selena; Simsek, Gokce; Simsek, Tugce; Robertson, Alastair; von Quadt, Albrecht; Köpke, Jürgen; Karaoglan, Fatih

    2016-04-01

    The Tauride belt ophiolites were generated above an intra-oceanic subduction zone and emplaced in the Late Cretaceous over the Tauride carbonate platform. The Tauride ophiolites are underlain by well-preserved metamorphic soles that have a constant structural position between the ophiolitic mélange, below and harzburgitic mantle tec- tonites, above. The dynamothermal metamorphic soles display a typical inverted metamorphic sequence, grading from amphibolite facies directly beneath the highly sheared harzburgitic tectonite to greenschist facies close to the melange contact. They display variable structural thickness (up to 500 m). The metamorphic soles beneath the Tauride ophiolites are interpreted to relate to the initiation of subduction and emplacement processes. The metamorphic soles are intruded by isolated post-metamorphic diabase dikes, derived from island arc tholeiitic magmas. In some places along the Tauride belt (Koycegiz and Pozanti-Karsanti regions), the contact between the metamorphic sole and the overlying serpentinized harzburgites is characterized by a 1.5-2 m thick zone of sheared serpentinized harzburgitic mantle tectonites, intercalated with amphibolites. These lithologies are cut by thick mafic dikes (7-8 m thick, individually) which postdate intraoceanic metamorphism and high-temperature ductile deformation. This contact is interpreted as an intra-oceanic decoupling surface along which volcanics in the upper levels of the down-going plate were metamorphosed to amphibolite facies and accreted to the base of the hanging wall plate. The geochemistry of the metamorphic sole amphibolites suggests their derivation from different geochemical environments; i.e. seamount-type alkaline basalts, mid-ocean ridge basalt (MORB) and island arc basalts. Zircon and rutile separates from the crustal rocks (gabbro and diabase) and from the metamorphic soles of the Tauride ophiolites have been dated by U-Pb SIMS (Edinburgh University) and LA-MC-ICP-MS (ETH Zurich

  17. CROWDSOURCING BASED 3D MODELING

    Directory of Open Access Journals (Sweden)

    A. Somogyi

    2016-06-01

    Full Text Available Web-based photo albums that support organizing and viewing the users’ images are widely used. These services provide a convenient solution for storing, editing and sharing images. In many cases, the users attach geotags to the images in order to enable using them e.g. in location based applications on social networks. Our paper discusses a procedure that collects open access images from a site frequently visited by tourists. Geotagged pictures showing the image of a sight or tourist attraction are selected and processed in photogrammetric processing software that produces the 3D model of the captured object. For the particular investigation we selected three attractions in Budapest. To assess the geometrical accuracy, we used laser scanner and DSLR as well as smart phone photography to derive reference values to enable verifying the spatial model obtained from the web-album images. The investigation shows how detailed and accurate models could be derived applying photogrammetric processing software, simply by using images of the community, without visiting the site.

  18. Orbital cellulitis as a sole symptom of odontogenic infection

    OpenAIRE

    Ngeow, W.C.

    1999-01-01

    A case of periapical infection resulting in unilateral maxillary sinusitis and cellulitis of the ipsilateral lower eyelid is presented. The sole symptom was right orbital swelling. The possible pathway for the spread of this type of infection predisposing factors and possible complications are reviewed. The value of radiographic examination and antibiotic therapy are also discussed. This record was migrated from the OpenDepot repository service in June, 2017 before shutting down.

  19. Mechanical behaviour of the Oman metamorphic sole: rheology of amphibolites at lower crustal conditions during subduction initiation

    Science.gov (United States)

    Soret, Mathieu; Agard, Philippe; Ildefonse, Benoît; Dubacq, Benoît; Prigent, Cécile; Yamato, Philippe

    2017-04-01

    Amphibolites are commonly found in the middle to lower continental crust and along oceanic transform faults and detachments. Amphibolites are also the main component of metamorphic soles beneath highly strained peridotites at the base of large-scale ophiolites as exemplified in Oman. Metamorphic soles are crustal slivers stripped from the slab during early subduction and underplated below the upper plate (future ophiolite) mantle when the subduction interface is still young and warm (i.e. during the first million years -My- of intra-oceanic subduction). Understanding the rheological behaviour of amphibolitic rocks is therefore of major interest to model and quantify deformation and strain localisation in varied geodynamical environments. This contribution focuses on the deformation mechanisms of amphibole through a microstructural and petrological study of garnet-bearing and garnet-free clinopyroxene-bearing amphibolites, using EBSD analysis. The first aim is to test the influence of progres- sive changes in PT conditions during deformation and of the appearance/disappearance of anhydrous minerals (plagioclase, clinopyroxene and garnet) on the mechanical behaviour of mafic amphibolites. The second aim is to track deformation mechanisms during early subduction, through the study of these metamorphosed oceanic rocks, commonly 10-100 m thick, which range from high- to low-grade away from the contact with the peridotites (i.e. from 800 ± 100˚C - 0.9 ± 0.2 GPa to 500 ± 100˚C - 0.5 ± 0.1 GPa) and are essentially mafic at the top). Our study points out the existence of two major steps of deformation in the high-temperature amphibolite slices of the metamorphic soles during the early subdduction dynamics. These two steps witness important mechanical coupling and progressive strain localization at plate interface under cooling and hydrated conditions after subduction initiation. During the accretion of the first slice of metamorphic sole at 850 ± 50˚C (the garnet

  20. Effect of ski mountaineering track on foot sole loading pattern.

    Science.gov (United States)

    Haselbacher, Matthias; Mader, Katharina; Werner, Maximiliane; Nogler, Michael

    2014-09-01

    Ski mountaineering is becoming a popular sport. The ascending techniques (tracks) can be divided into 3 different groups: flat field, direct ascent, and traversing. This study examines the relationship between different mechanical loads on the foot and the 4 different mountaineering ascending techniques. All subjects used the same pair of ski boots and the same skis while performing the 4 different ascending techniques. An in-shoe dynamic pressure measuring system was used to measure the mechanical load on the foot soles of each ski mountaineer. The foot sole was divided into 6 anatomic sections to measure the different loads in each section. Thirteen men with an average age of 29 years were enrolled in the study. The results showed small, not significant differences in the mechanical foot load in the flat field or in the direct ascent. The average mechanical foot load was highest on the valley side foot while traversing (179 kPa to 117 kPa). The higher load forces were in the medial ball of the foot and the longitudinal aspect of the foot side closer to the hill. The higher impact placed on the valley side foot and the concentration of force placed on the medial ball of the valley side foot suggested the influence of the track on the load pattern of the foot sole. This higher impact may result in upward forces that affect the force distribution in the ankle and knee joints. Copyright © 2014. Published by Elsevier Inc.

  1. Computer Based Modelling and Simulation

    Indian Academy of Sciences (India)

    leaving students. It is a probabilistic model. In the next part of this article, two more models - 'input/output model' used for production systems or economic studies and a. 'discrete event simulation model' are introduced. Aircraft Performance Model.

  2. Sensor-based interior modeling

    International Nuclear Information System (INIS)

    Herbert, M.; Hoffman, R.; Johnson, A.; Osborn, J.

    1995-01-01

    Robots and remote systems will play crucial roles in future decontamination and decommissioning (D ampersand D) of nuclear facilities. Many of these facilities, such as uranium enrichment plants, weapons assembly plants, research and production reactors, and fuel recycling facilities, are dormant; there is also an increasing number of commercial reactors whose useful lifetime is nearly over. To reduce worker exposure to radiation, occupational and other hazards associated with D ampersand D tasks, robots will execute much of the work agenda. Traditional teleoperated systems rely on human understanding (based on information gathered by remote viewing cameras) of the work environment to safely control the remote equipment. However, removing the operator from the work site substantially reduces his efficiency and effectiveness. To approach the productivity of a human worker, tasks will be performed telerobotically, in which many aspects of task execution are delegated to robot controllers and other software. This paper describes a system that semi-automatically builds a virtual world for remote D ampersand D operations by constructing 3-D models of a robot's work environment. Planar and quadric surface representations of objects typically found in nuclear facilities are generated from laser rangefinder data with a minimum of human interaction. The surface representations are then incorporated into a task space model that can be viewed and analyzed by the operator, accessed by motion planning and robot safeguarding algorithms, and ultimately used by the operator to instruct the robot at a level much higher than teleoperation

  3. Eclissi! Quando Sole e Luna danno spettacolo in cielo

    CERN Document Server

    Bastoni, Marco

    2012-01-01

    Le eclissi di Sole e di Luna sono fra gli spettacoli più avvincenti della Natura; questo libro è una guida completa alla loro osservazione e spiega come cercare, vivere e fotografare questi eventi senza necessariamente essere astrofili esperti. Cosa posso osservare durante un’eclisse? Da dove? E quando? Un’accurata selezione delle 10 eclissi imperdibili da qui al 2050 chiude l’opera, aiutando il lettore nella pianificazione delle osservazioni. Preparate i bagagli, guardate l’eclisse e lasciatevi emozionare!

  4. Differential geometry based multiscale models.

    Science.gov (United States)

    Wei, Guo-Wei

    2010-08-01

    Large chemical and biological systems such as fuel cells, ion channels, molecular motors, and viruses are of great importance to the scientific community and public health. Typically, these complex systems in conjunction with their aquatic environment pose a fabulous challenge to theoretical description, simulation, and prediction. In this work, we propose a differential geometry based multiscale paradigm to model complex macromolecular systems, and to put macroscopic and microscopic descriptions on an equal footing. In our approach, the differential geometry theory of surfaces and geometric measure theory are employed as a natural means to couple the macroscopic continuum mechanical description of the aquatic environment with the microscopic discrete atomistic description of the macromolecule. Multiscale free energy functionals, or multiscale action functionals are constructed as a unified framework to derive the governing equations for the dynamics of different scales and different descriptions. Two types of aqueous macromolecular complexes, ones that are near equilibrium and others that are far from equilibrium, are considered in our formulations. We show that generalized Navier-Stokes equations for the fluid dynamics, generalized Poisson equations or generalized Poisson-Boltzmann equations for electrostatic interactions, and Newton's equation for the molecular dynamics can be derived by the least action principle. These equations are coupled through the continuum-discrete interface whose dynamics is governed by potential driven geometric flows. Comparison is given to classical descriptions of the fluid and electrostatic interactions without geometric flow based micro-macro interfaces. The detailed balance of forces is emphasized in the present work. We further extend the proposed multiscale paradigm to micro-macro analysis of electrohydrodynamics, electrophoresis, fuel cells, and ion channels. We derive generalized Poisson-Nernst-Planck equations that are

  5. Differential Geometry Based Multiscale Models

    Science.gov (United States)

    Wei, Guo-Wei

    2010-01-01

    Large chemical and biological systems such as fuel cells, ion channels, molecular motors, and viruses are of great importance to the scientific community and public health. Typically, these complex systems in conjunction with their aquatic environment pose a fabulous challenge to theoretical description, simulation, and prediction. In this work, we propose a differential geometry based multiscale paradigm to model complex macromolecular systems, and to put macroscopic and microscopic descriptions on an equal footing. In our approach, the differential geometry theory of surfaces and geometric measure theory are employed as a natural means to couple the macroscopic continuum mechanical description of the aquatic environment with the microscopic discrete atom-istic description of the macromolecule. Multiscale free energy functionals, or multiscale action functionals are constructed as a unified framework to derive the governing equations for the dynamics of different scales and different descriptions. Two types of aqueous macromolecular complexes, ones that are near equilibrium and others that are far from equilibrium, are considered in our formulations. We show that generalized Navier–Stokes equations for the fluid dynamics, generalized Poisson equations or generalized Poisson–Boltzmann equations for electrostatic interactions, and Newton's equation for the molecular dynamics can be derived by the least action principle. These equations are coupled through the continuum-discrete interface whose dynamics is governed by potential driven geometric flows. Comparison is given to classical descriptions of the fluid and electrostatic interactions without geometric flow based micro-macro interfaces. The detailed balance of forces is emphasized in the present work. We further extend the proposed multiscale paradigm to micro-macro analysis of electrohydrodynamics, electrophoresis, fuel cells, and ion channels. We derive generalized Poisson–Nernst–Planck equations that

  6. Observation-Based Modeling for Model-Based Testing

    NARCIS (Netherlands)

    Kanstrén, T.; Piel, E.; Gross, H.G.

    2009-01-01

    One of the single most important reasons that modeling and modelbased testing are not yet common practice in industry is the perceived difficulty of making the models up to the level of detail and quality required for their automated processing. Models unleash their full potential only through

  7. Single Locus Maintains Large Variation of Sex Reversal in Half-Smooth Tongue Sole (Cynoglossus semilaevis).

    Science.gov (United States)

    Jiang, Li; Li, Hengde

    2017-02-09

    Sex determination is a fundamental biological process for individual sex development and population sex ratios. However, for some species, the primary sex might be altered during development, and individuals can develop into the opposite sex. Sex reversal may happen in insects, reptiles, amphibians, and fishes. In half-smooth tongue sole ( Cynoglossus semilaevis ), some genetically female fish irreversibly reverse to pseudomales, resulting in higher costs in aquaculture owing to a lower growth rate of male fish during a 2-yr growth period. Here, we identified a locus with large controlling effect on sex reversal in the half-smooth tongue sole through genome-wide association study with high-density single nucleotide polymorphisms (SNPs). This SNP is located at the third intron of the F-box and leucine rich repeat protein 17 ( FBXL17 ) gene on the Z chromosome, and it has two alleles, A and T. Genetic females with Z A W genotypes will never reverse into phenotypic males, but those with Z T W genotypes can sometimes undergo sex reversal. This SNP explains 82.7% of the genetic variation, or 58.4% of the phenotypic variation. Based on our results, a reproductive management program could be developed to improve the phenotypic female ratio in aquaculture, and elucidate the mechanism of sex reversal in half-smooth tongue sole. We expect that these findings will have a substantial impact on the population management in many harvested species where sex reversal occurs. Copyright © 2017 Jiang and Li.

  8. Single Locus Maintains Large Variation of Sex Reversal in Half-Smooth Tongue Sole (Cynoglossus semilaevis

    Directory of Open Access Journals (Sweden)

    Li Jiang

    2017-02-01

    Full Text Available Sex determination is a fundamental biological process for individual sex development and population sex ratios. However, for some species, the primary sex might be altered during development, and individuals can develop into the opposite sex. Sex reversal may happen in insects, reptiles, amphibians, and fishes. In half-smooth tongue sole (Cynoglossus semilaevis, some genetically female fish irreversibly reverse to pseudomales, resulting in higher costs in aquaculture owing to a lower growth rate of male fish during a 2-yr growth period. Here, we identified a locus with large controlling effect on sex reversal in the half-smooth tongue sole through genome-wide association study with high-density single nucleotide polymorphisms (SNPs. This SNP is located at the third intron of the F-box and leucine rich repeat protein 17 (FBXL17 gene on the Z chromosome, and it has two alleles, A and T. Genetic females with ZAW genotypes will never reverse into phenotypic males, but those with ZTW genotypes can sometimes undergo sex reversal. This SNP explains 82.7% of the genetic variation, or 58.4% of the phenotypic variation. Based on our results, a reproductive management program could be developed to improve the phenotypic female ratio in aquaculture, and elucidate the mechanism of sex reversal in half-smooth tongue sole. We expect that these findings will have a substantial impact on the population management in many harvested species where sex reversal occurs.

  9. Inherent variation in multiple shoe-sole test impressions.

    Science.gov (United States)

    Shor, Yaron; Wiesner, Sarena; Tsach, Tsadok; Gurel, Ron; Yekutieli, Yoram

    2018-04-01

    Shoeprints left at crime scenes are seldom perfect. Many prints are distorted or contaminated by various materials. Noisy background often contributes to vagueness on the shoeprints as well. Test impressions made from the suspect's shoes in the laboratory are considered a genuine replication of the shoe-sole. This naïve attitude is far from being correct. Consecutive test impressions made in the laboratory under strict similar conditions revealed differences among the exemplars of the same sole. Some of them are minor, but some are major, and can mislead the less experienced practitioners during the comparison process. This article focuses on the inherent within source variability between controlled shoeprints made from the same shoe, as it appears on the RACs. To describe and analyze this variability, repeated test impressions were prepared, and datasets were created. Several RACs were marked on each test impression, using an expert assisting software tool (developed in the authors' lab). The variance in repeated test impressions is demonstrated and possible sources are discussed. This variance should be considered when trying to establish the degree of matching between individual characteristics. Copyright © 2017. Published by Elsevier B.V.

  10. Guide to APA-Based Models

    Science.gov (United States)

    Robins, Robert E.; Delisi, Donald P.

    2008-01-01

    In Robins and Delisi (2008), a linear decay model, a new IGE model by Sarpkaya (2006), and a series of APA-Based models were scored using data from three airports. This report is a guide to the APA-based models.

  11. Relational Resilience in Māori, Pacific, and European Sole Parent Families: From Theory and Research to Social Policy.

    Science.gov (United States)

    Waldegrave, Charles; King, Peter; Maniapoto, Maria; Tamasese, Taimalieutu Kiwi; Parsons, Tafaoimalo Loudeen; Sullivan, Ginny

    2016-12-01

    This study reports findings and policy recommendations from a research project that applied a relational resilience framework to a study of 60 sole parent families in New Zealand, with approximately equal numbers of Māori, Pacific, and European (White) participants. The sole parent families involved were already known to be resilient and the study focused on identifying the relationships and strategies underlying the achievement and maintenance of their resilience. The study was carried out to provide an evidence base for the development and implementation of policies and interventions to both support sole parent families who have achieved resilience and assist those who struggle to do so. The three populations shared many similarities in their pathways to becoming sole parents and the challenges they faced as sole parents. The coping strategies underlying their demonstrated resilience were also broadly similar, but the ways in which they were carried out did vary in a manner that particularly reflected cultural practices in terms of their reliance upon extended family-based support or support from outside the family. The commonalities support the appropriateness of the common conceptual framework used, whereas the differences underline the importance of developing nuanced policy responses that take into account cultural differences between the various populations to which policy initiatives are directed. © 2016 Family Process Institute.

  12. Constraint-Based Model Weaving

    Science.gov (United States)

    White, Jules; Gray, Jeff; Schmidt, Douglas C.

    Aspect-oriented modeling (AOM) is a promising technique for untangling the concerns of complex enterprise software systems. AOM decomposes the crosscutting concerns of a model into separate models that can be woven together to form a composite solution model. In many domains, such as multi-tiered e-commerce web applications, separating concerns is much easier than deducing the proper way to weave the concerns back together into a solution model. For example, modeling the types and sizes of caches that can be leveraged by a Web application is much easier than deducing the optimal way to weave the caches back into the solution architecture to achieve high system throughput.

  13. gis-based hydrological model based hydrological model upstream

    African Journals Online (AJOL)

    eobe

    its effectiveness in terms of data representation quality of modeling results, hydrological models usually embedded in Geographical Information. (GIS) environment to simulate various parame attributed to a selected catchment. complex technology highly suitable for spatial temporal data analyses and information extractio.

  14. Rule-based decision making model

    International Nuclear Information System (INIS)

    Sirola, Miki

    1998-01-01

    A rule-based decision making model is designed in G2 environment. A theoretical and methodological frame for the model is composed and motivated. The rule-based decision making model is based on object-oriented modelling, knowledge engineering and decision theory. The idea of safety objective tree is utilized. Advanced rule-based methodologies are applied. A general decision making model 'decision element' is constructed. The strategy planning of the decision element is based on e.g. value theory and utility theory. A hypothetical process model is built to give input data for the decision element. The basic principle of the object model in decision making is division in tasks. Probability models are used in characterizing component availabilities. Bayes' theorem is used to recalculate the probability figures when new information is got. The model includes simple learning features to save the solution path. A decision analytic interpretation is given to the decision making process. (author)

  15. Influence of ambient oxygenation and temperature on metabolic scope and scope for heart rate in the common sole Solea solea

    OpenAIRE

    Lefrancois, Christelle; Claireaux, Guy

    2003-01-01

    The objective of this study was to quantify the constraints exerted by temperature and oxygenation on both metabolic scope and scope for heart rate of the common sole Solea solea. We exposed sole to a large range of temperature and oxygenation conditions and a modelling procedure was implemented to describe metabolic and cardiac responses. Standard metabolic rate (SMR) rose exponentially from 4 to 24degreesC, whereas active metabolic rate (AMR) increased from 55.4 to 159.2 mgO(2) kg(-1) h(-1)...

  16. Computer Based Modelling and Simulation

    Indian Academy of Sciences (India)

    Most systems involve parameters and variables, which are random variables due to uncertainties. Probabilistic meth- ods are powerful in modelling such systems. In this second part, we describe probabilistic models and Monte Carlo simulation along with 'classical' matrix methods and differ- ential equations as most real ...

  17. Computer Based Modelling and Simulation

    Indian Academy of Sciences (India)

    A familiar example of a feedback loop is the business model in which part of the output or profit is fedback as input or additional capital - for instance, a company may choose to reinvest 10% of the profit for expansion of the business. Such simple models, like ..... would help scientists, engineers and managers towards better.

  18. Model based design introduction: modeling game controllers to microprocessor architectures

    Science.gov (United States)

    Jungwirth, Patrick; Badawy, Abdel-Hameed

    2017-04-01

    We present an introduction to model based design. Model based design is a visual representation, generally a block diagram, to model and incrementally develop a complex system. Model based design is a commonly used design methodology for digital signal processing, control systems, and embedded systems. Model based design's philosophy is: to solve a problem - a step at a time. The approach can be compared to a series of steps to converge to a solution. A block diagram simulation tool allows a design to be simulated with real world measurement data. For example, if an analog control system is being upgraded to a digital control system, the analog sensor input signals can be recorded. The digital control algorithm can be simulated with the real world sensor data. The output from the simulated digital control system can then be compared to the old analog based control system. Model based design can compared to Agile software develop. The Agile software development goal is to develop working software in incremental steps. Progress is measured in completed and tested code units. Progress is measured in model based design by completed and tested blocks. We present a concept for a video game controller and then use model based design to iterate the design towards a working system. We will also describe a model based design effort to develop an OS Friendly Microprocessor Architecture based on the RISC-V.

  19. The Culture Based Model: Constructing a Model of Culture

    Science.gov (United States)

    Young, Patricia A.

    2008-01-01

    Recent trends reveal that models of culture aid in mapping the design and analysis of information and communication technologies. Therefore, models of culture are powerful tools to guide the building of instructional products and services. This research examines the construction of the culture based model (CBM), a model of culture that evolved…

  20. Base Flow Model Validation Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The innovation is the systematic "building-block" validation of CFD/turbulence models employing a GUI driven CFD code (RPFM) and existing as well as new data sets to...

  1. Model-Based Enterprise Summit Report

    Science.gov (United States)

    2014-02-01

    Models Become Much More Efficient and Effective When Coupled With Knowledge Design Advisors CAD Fit Machine Motion KanBan Trigger Models Tolerance...Based Enterprise Geometry Kinematics Design Advisors Control Physics Planning System Models CAD Fit Machine Motion KanBan Trigger Models Tolerance

  2. Traceability in Model-Based Testing

    Directory of Open Access Journals (Sweden)

    Mathew George

    2012-11-01

    Full Text Available The growing complexities of software and the demand for shorter time to market are two important challenges that face today’s IT industry. These challenges demand the increase of both productivity and quality of software. Model-based testing is a promising technique for meeting these challenges. Traceability modeling is a key issue and challenge in model-based testing. Relationships between the different models will help to navigate from one model to another, and trace back to the respective requirements and the design model when the test fails. In this paper, we present an approach for bridging the gaps between the different models in model-based testing. We propose relation definition markup language (RDML for defining the relationships between models.

  3. Firm Based Trade Models and Turkish Economy

    Directory of Open Access Journals (Sweden)

    Nilüfer ARGIN

    2015-12-01

    Full Text Available Among all international trade models, only The Firm Based Trade Models explains firm’s action and behavior in the world trade. The Firm Based Trade Models focuses on the trade behavior of individual firms that actually make intra industry trade. Firm Based Trade Models can explain globalization process truly. These approaches include multinational cooperation, supply chain and outsourcing also. Our paper aims to explain and analyze Turkish export with Firm Based Trade Models’ context. We use UNCTAD data on exports by SITC Rev 3 categorization to explain total export and 255 products and calculate intensive-extensive margins of Turkish firms.

  4. Lévy-based growth models

    DEFF Research Database (Denmark)

    Jónsdóttir, Kristjana Ýr; Schmiegel, Jürgen; Jensen, Eva Bjørn Vedel

    2008-01-01

    In the present paper, we give a condensed review, for the nonspecialist reader, of a new modelling framework for spatio-temporal processes, based on Lévy theory. We show the potential of the approach in stochastic geometry and spatial statistics by studying Lévy-based growth modelling of planar o...... objects. The growth models considered are spatio-temporal stochastic processes on the circle. As a by product, flexible new models for space–time covariance functions on the circle are provided. An application of the Lévy-based growth models to tumour growth is discussed....

  5. Distributed Prognostics Based on Structural Model Decomposition

    Data.gov (United States)

    National Aeronautics and Space Administration — Within systems health management, prognostics focuses on predicting the remaining useful life of a system. In the model-based prognostics paradigm, physics-based...

  6. Computer Based Modelling and Simulation

    Indian Academy of Sciences (India)

    Modelling Deterministic Systems. N K Srinivasan gradu- ated from Indian. Institute of Science and obtained his Doctorate from Columbia Univer- sity, New York. He has taught in several universities, and later did system analysis, wargaming and simula- tion for defence. His other areas of interest are reliability engineer-.

  7. Ammonium as sole N source improves grain quality in wheat.

    Science.gov (United States)

    Fuertes-Mendizábal, Teresa; González-Torralba, Jon; Arregui, Luis M; González-Murua, Carmen; González-Moro, M Begoña; Estavillo, José M

    2013-07-01

    The skilful handling of N fertilizer, including N source type and its timing, is necessary to obtain maximum profitability in wheat crops in terms of production and quality. Studies on grain yield and quality with ammonium as sole N source have not yet been conducted. The aim of this study was to evaluate the effect of N source management (nitrate vs. ammonium), and splitting it into two or three amendments during the wheat life cycle, on grain yield and quality under irrigated conditions. This experiment demonstrates that Cezanne wheat plants growing with ammonium as exclusive N source are able to achieve the same yield as plants growing with nitrate and that individual wheat plants grown in irrigated pots can efficiently use late N applied in GS37. Ammonium nutrition increased both types of grain reserve proteins (gliadins and glutenins) and also increased the ratio gli/glu with respect to nitrate nutrition. The splitting of the N rate enhanced the ammonium effect on grain protein composition. The application of ammonium N source, especially when split into three amendments, has an analogous effect on grain protein content and composition to applications at a higher N rate, leading to higher N use efficiency. © 2012 Society of Chemical Industry.

  8. Sole-Source Lighting for Controlled-Environment Agriculture

    Science.gov (United States)

    Mitchell.Cary; Stutte, Gary W.

    2015-01-01

    Since plants on Earth evolved under broad-spectrum solar radiation, anytime they are grown exclusively under electric lighting that does not contain all wavelengths in similar proportion to those in sunlight, plant appearance and size could be uniquely different. Nevertheless, plants have been grown for decades under fluorescent (FL) (1) + incandescent (IN) (2) lamps as a sole source of lighting (SSL), and researchers have become comfortable that, in certain proportions of FL + IN for a given species, plants can appear "normal" relative to their growth outdoors. The problem with using such traditional SSLs for commercial production typically is short lamp lifespans and not obtaining enough photosynthetically active radiation (PAR, 400-700 nm) when desired. These limitations led to supplementation of FL + IN lamp outputs with longer-lived, high-intensity discharge (HID) lamps in growth chambers (3). As researchers became comfortable that mixes of orange-biased high-pressure sodium (HPS) and blue-biased metal halide (MH) HIDs together also could give normal plant growth at higher intensities, growth chambers and phytotrons subsequently were equipped mainly with HID lamps, with their intense thermal output filtered out by ventilated light caps or thermal-controlled water barriers. For the most part, IN and HID lamps have found a home in commercial protected horticulture, usually for night-break photoperiod lighting (IN) or for seasonal supplemental lighting (mostly HPS) in greenhouses. However, lack of economically viable options for SSL have held back aspects of year-round indoor agriculture from taking off commercially.

  9. Residual-based model diagnosis methods for mixture cure models.

    Science.gov (United States)

    Peng, Yingwei; Taylor, Jeremy M G

    2017-06-01

    Model diagnosis, an important issue in statistical modeling, has not yet been addressed adequately for cure models. We focus on mixture cure models in this work and propose some residual-based methods to examine the fit of the mixture cure model, particularly the fit of the latency part of the mixture cure model. The new methods extend the classical residual-based methods to the mixture cure model. Numerical work shows that the proposed methods are capable of detecting lack-of-fit of a mixture cure model, particularly in the latency part, such as outliers, improper covariate functional form, or nonproportionality in hazards if the proportional hazards assumption is employed in the latency part. The methods are illustrated with two real data sets that were previously analyzed with mixture cure models. © 2016, The International Biometric Society.

  10. Model Validation in Ontology Based Transformations

    Directory of Open Access Journals (Sweden)

    Jesús M. Almendros-Jiménez

    2012-10-01

    Full Text Available Model Driven Engineering (MDE is an emerging approach of software engineering. MDE emphasizes the construction of models from which the implementation should be derived by applying model transformations. The Ontology Definition Meta-model (ODM has been proposed as a profile for UML models of the Web Ontology Language (OWL. In this context, transformations of UML models can be mapped into ODM/OWL transformations. On the other hand, model validation is a crucial task in model transformation. Meta-modeling permits to give a syntactic structure to source and target models. However, semantic requirements have to be imposed on source and target models. A given transformation will be sound when source and target models fulfill the syntactic and semantic requirements. In this paper, we present an approach for model validation in ODM based transformations. Adopting a logic programming based transformational approach we will show how it is possible to transform and validate models. Properties to be validated range from structural and semantic requirements of models (pre and post conditions to properties of the transformation (invariants. The approach has been applied to a well-known example of model transformation: the Entity-Relationship (ER to Relational Model (RM transformation.

  11. An acoustical model based monitoring network

    NARCIS (Netherlands)

    Wessels, P.W.; Basten, T.G.H.; Eerden, F.J.M. van der

    2010-01-01

    In this paper the approach for an acoustical model based monitoring network is demonstrated. This network is capable of reconstructing a noise map, based on the combination of measured sound levels and an acoustic model of the area. By pre-calculating the sound attenuation within the network the

  12. Model-based version management system framework

    International Nuclear Information System (INIS)

    Mehmood, W.

    2016-01-01

    In this paper we present a model-based version management system. Version Management System (VMS) a branch of software configuration management (SCM) aims to provide a controlling mechanism for evolution of software artifacts created during software development process. Controlling the evolution requires many activities to perform, such as, construction and creation of versions, identification of differences between versions, conflict detection and merging. Traditional VMS systems are file-based and consider software systems as a set of text files. File based VMS systems are not adequate for performing software configuration management activities such as, version control on software artifacts produced in earlier phases of the software life cycle. New challenges of model differencing, merge, and evolution control arise while using models as central artifact. The goal of this work is to present a generic framework model-based VMS which can be used to overcome the problem of tradition file-based VMS systems and provide model versioning services. (author)

  13. Gradient-based model calibration with proxy-model assistance

    Science.gov (United States)

    Burrows, Wesley; Doherty, John

    2016-02-01

    Use of a proxy model in gradient-based calibration and uncertainty analysis of a complex groundwater model with large run times and problematic numerical behaviour is described. The methodology is general, and can be used with models of all types. The proxy model is based on a series of analytical functions that link all model outputs used in the calibration process to all parameters requiring estimation. In enforcing history-matching constraints during the calibration and post-calibration uncertainty analysis processes, the proxy model is run for the purposes of populating the Jacobian matrix, while the original model is run when testing parameter upgrades; the latter process is readily parallelized. Use of a proxy model in this fashion dramatically reduces the computational burden of complex model calibration and uncertainty analysis. At the same time, the effect of model numerical misbehaviour on calculation of local gradients is mitigated, this allowing access to the benefits of gradient-based analysis where lack of integrity in finite-difference derivatives calculation would otherwise have impeded such access. Construction of a proxy model, and its subsequent use in calibration of a complex model, and in analysing the uncertainties of predictions made by that model, is implemented in the PEST suite.

  14. PV panel model based on datasheet values

    DEFF Research Database (Denmark)

    Sera, Dezso; Teodorescu, Remus; Rodriguez, Pedro

    2007-01-01

    This work presents the construction of a model for a PV panel using the single-diode five-parameters model, based exclusively on data-sheet parameters. The model takes into account the series and parallel (shunt) resistance of the panel. The equivalent circuit and the basic equations of the PV cell...

  15. Model-Based Design for Embedded Systems

    CERN Document Server

    Nicolescu, Gabriela

    2009-01-01

    Model-based design allows teams to start the design process from a high-level model that is gradually refined through abstraction levels to ultimately yield a prototype. This book describes the main facets of heterogeneous system design. It focuses on multi-core methodological issues, real-time analysis, and modeling and validation

  16. Agent-based modeling of sustainable behaviors

    CERN Document Server

    Sánchez-Maroño, Noelia; Fontenla-Romero, Oscar; Polhill, J; Craig, Tony; Bajo, Javier; Corchado, Juan

    2017-01-01

    Using the O.D.D. (Overview, Design concepts, Detail) protocol, this title explores the role of agent-based modeling in predicting the feasibility of various approaches to sustainability. The chapters incorporated in this volume consist of real case studies to illustrate the utility of agent-based modeling and complexity theory in discovering a path to more efficient and sustainable lifestyles. The topics covered within include: households' attitudes toward recycling, designing decision trees for representing sustainable behaviors, negotiation-based parking allocation, auction-based traffic signal control, and others. This selection of papers will be of interest to social scientists who wish to learn more about agent-based modeling as well as experts in the field of agent-based modeling.

  17. Background based Gaussian mixture model lesion segmentation in PET

    Energy Technology Data Exchange (ETDEWEB)

    Soffientini, Chiara Dolores, E-mail: chiaradolores.soffientini@polimi.it; Baselli, Giuseppe [DEIB, Department of Electronics, Information, and Bioengineering, Politecnico di Milano, Piazza Leonardo da Vinci 32, Milan 20133 (Italy); De Bernardi, Elisabetta [Department of Medicine and Surgery, Tecnomed Foundation, University of Milano—Bicocca, Monza 20900 (Italy); Zito, Felicia; Castellani, Massimo [Nuclear Medicine Department, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, via Francesco Sforza 35, Milan 20122 (Italy)

    2016-05-15

    demonstrated. The inclusion of the spatial prior improved segmentation accuracy only for lesions surrounded by heterogeneous background: in the relevant simulation subset, the median VE significantly decreased from 13% to 7%. Results on clinical data were found in accordance with simulations, with absolute VE <7%, Dice >0.85, CE <0.30, and HD <0.81. Conclusions: The sole introduction of constraints based on background modeling outperformed standard GMM and the other tested algorithms. Insertion of a spatial prior improved the accuracy for realistic cases of objects in heterogeneous backgrounds. Moreover, robustness against initialization supports the applicability in a clinical setting. In conclusion, application-driven constraints can generally improve the capabilities of GMM and statistical clustering algorithms.

  18. Model-based Abstraction of Data Provenance

    DEFF Research Database (Denmark)

    Probst, Christian W.; Hansen, René Rydhof

    2014-01-01

    to bigger models, and the analyses adapt accordingly. Our approach extends provenance both with the origin of data, the actors and processes involved in the handling of data, and policies applied while doing so. The model and corresponding analyses are based on a formal model of spatial and organisational......Identifying provenance of data provides insights to the origin of data and intermediate results, and has recently gained increased interest due to data-centric applications. In this work we extend a data-centric system view with actors handling the data and policies restricting actions....... This extension is based on provenance analysis performed on system models. System models have been introduced to model and analyse spatial and organisational aspects of organisations, to identify, e.g., potential insider threats. Both the models and analyses are naturally modular; models can be combined...

  19. Culturicon model: A new model for cultural-based emoticon

    Science.gov (United States)

    Zukhi, Mohd Zhafri Bin Mohd; Hussain, Azham

    2017-10-01

    Emoticons are popular among distributed collective interaction user in expressing their emotion, gestures and actions. Emoticons have been proved to be able to avoid misunderstanding of the message, attention saving and improved the communications among different native speakers. However, beside the benefits that emoticons can provide, the study regarding emoticons in cultural perspective is still lacking. As emoticons are crucial in global communication, culture should be one of the extensively research aspect in distributed collective interaction. Therefore, this study attempt to explore and develop model for cultural-based emoticon. Three cultural models that have been used in Human-Computer Interaction were studied which are the Hall Culture Model, Trompenaars and Hampden Culture Model and Hofstede Culture Model. The dimensions from these three models will be used in developing the proposed cultural-based emoticon model.

  20. Agent-based modeling and network dynamics

    CERN Document Server

    Namatame, Akira

    2016-01-01

    The book integrates agent-based modeling and network science. It is divided into three parts, namely, foundations, primary dynamics on and of social networks, and applications. The book begins with the network origin of agent-based models, known as cellular automata, and introduce a number of classic models, such as Schelling’s segregation model and Axelrod’s spatial game. The essence of the foundation part is the network-based agent-based models in which agents follow network-based decision rules. Under the influence of the substantial progress in network science in late 1990s, these models have been extended from using lattices into using small-world networks, scale-free networks, etc. The book also shows that the modern network science mainly driven by game-theorists and sociophysicists has inspired agent-based social scientists to develop alternative formation algorithms, known as agent-based social networks. The book reviews a number of pioneering and representative models in this family. Upon the gi...

  1. CEAI: CCM based Email Authorship Identification Model

    DEFF Research Database (Denmark)

    Nizamani, Sarwat; Memon, Nasrullah

    2013-01-01

    In this paper we present a model for email authorship identification (EAI) by employing a Cluster-based Classification (CCM) technique. Traditionally, stylometric features have been successfully employed in various authorship analysis tasks; we extend the traditional feature-set to include some...... reveal that the proposed CCM-based email authorship identification model, along with the proposed feature set, outperforms the state-of-the-art support vector machine (SVM)-based models, as well as the models proposed by Iqbal et al. [1, 2]. The proposed model attains an accuracy rate of 94% for 10...... authors, 89% for 25 authors, and 81% for 50 authors, respectively on Enron data set, while 89.5% accuracy has been achieved on authors' constructed real email data set. The results on Enron data set have been achieved on quite a large number of authors as compared to the models proposed by Iqbal et al. [1...

  2. Integration of Simulink Models with Component-based Software Models

    Directory of Open Access Journals (Sweden)

    MARIAN, N.

    2008-06-01

    Full Text Available Model based development aims to facilitate the development of embedded control systems by emphasizing the separation of the design level from the implementation level. Model based design involves the use of multiple models that represent different views of a system, having different semantics of abstract system descriptions. Usually, in mechatronics systems, design proceeds by iterating model construction, model analysis, and model transformation. Constructing a MATLAB/Simulink model, a plant and controller behavior is simulated using graphical blocks to represent mathematical and logical constructs and process flow, then software code is generated. A Simulink model is a representation of the design or implementation of a physical system that satisfies a set of requirements. A software component-based system aims to organize system architecture and behavior as a means of computation, communication and constraints, using computational blocks and aggregates for both discrete and continuous behavior, different interconnection and execution disciplines for event-based and time-based controllers, and so on, to encompass the demands to more functionality, at even lower prices, and with opposite constraints. COMDES (Component-based Design of Software for Distributed Embedded Systems is such a component-based system framework developed by the software engineering group of Mads Clausen Institute for Product Innovation (MCI, University of Southern Denmark. Once specified, the software model has to be analyzed. One way of doing that is to integrate in wrapper files the model back into Simulink S-functions, and use its extensive simulation features, thus allowing an early exploration of the possible design choices over multiple disciplines. The paper describes a safe translation of a restricted set of MATLAB/Simulink blocks to COMDES software components, both for continuous and discrete behavior, and the transformation of the software system into the S

  3. Clinical assessment of dynamic coefficient of friction effects in shoe-sole trituration of patients with drop foot.

    Science.gov (United States)

    Nima, Jamshidi; Firooz, Salami

    2012-06-01

    The aim of this study was examining the effect of human factors such as plantar friction, contact period time, and impulse on shoe-sole trituration of drop foot patients. Twenty-five patients with drop foot and twenty normal subjects were recruited in the study. The force plate and its related software's recorded human factor (coefficient of friction, ground reaction force, time of stance phase) as time dependent parameters. Dynamic coefficient of friction patterns were categorized based on their magnitude versus time when the longitudinal axis of the sole was plotted as the Y-axis and the transverse axis of the sole as X-axis during stance phase. The result of this research indicated that the average coefficient of friction among drop foot patients is 77.53 % (p value <0.05) lower than the normal subjects. Also the time of stance phase among drop foot patients is 7.56 % (p value <0.05) greater than normal subjects. There is no difference in the peaks, of vertical ground reaction force between normal and control group. The findings of this research revealed that the time of stance phase has a key role in shoe-sole trituration of patients with drop foot.

  4. Isolation and characterization of pathogenic Listonella anguillarum of diseased half-smooth tongue sole ( Cynoglossus semilaevis Günther)

    Science.gov (United States)

    Tang, Xiaoqian; Zhou, Li; Zhan, Wenbin

    2008-08-01

    Studies were conducted to determine the cause of the acute mortality of half-smooth tongue sole Cynoglossus semilaevis Günther juveniles in a fish farm in Jimo, Shandong Province, China, in June 2006. Gross signs of the diseased tongue sole included several petechiae and ecchymoses on the body and fin necrosis and hemorrhagic lesion at the base of the fin. Bacteria were isolated from kidney, liver and hemorrhagic lesions of the diseased tongue sole. Among14 strains, SJ060621 was proved to be highly virulent to juvenile tongue sole with LD50 value of antibiotics tested, SJ060621 was sensitive to gentamicin and nitrofurantoin. It was identified as Listonella anguillarum with conventional plate and tube tests in combination with API 20E analysis. 16S rRNA gene and partial HSP60 gene sequenceing analysis revealed that the strain was highly homologous with L. anguillarum. Examination of the infected musculature by electron microscopy indicated numerous bacteria and lots of macrophages containing phagocytosed bacteria. Histopathological investigations revealed severe necrotic degenerative changes in the infected organs. Indirect immunofluorescence assay (IFA) was employed to detect the location of occurrence of bacteria, and bacteria were found in aggregations in the inflammatory areas in musculature.

  5. Business Process Modelling based on Petri nets

    Directory of Open Access Journals (Sweden)

    Qin Jianglong

    2017-01-01

    Full Text Available Business process modelling is the way business processes are expressed. Business process modelling is the foundation of business process analysis, reengineering, reorganization and optimization. It can not only help enterprises to achieve internal information system integration and reuse, but also help enterprises to achieve with the external collaboration. Based on the prototype Petri net, this paper adds time and cost factors to form an extended generalized stochastic Petri net. It is a formal description of the business process. The semi-formalized business process modelling algorithm based on Petri nets is proposed. Finally, The case from a logistics company proved that the modelling algorithm is correct and effective.

  6. Instance-Based Generative Biological Shape Modeling.

    Science.gov (United States)

    Peng, Tao; Wang, Wei; Rohde, Gustavo K; Murphy, Robert F

    2009-01-01

    Biological shape modeling is an essential task that is required for systems biology efforts to simulate complex cell behaviors. Statistical learning methods have been used to build generative shape models based on reconstructive shape parameters extracted from microscope image collections. However, such parametric modeling approaches are usually limited to simple shapes and easily-modeled parameter distributions. Moreover, to maximize the reconstruction accuracy, significant effort is required to design models for specific datasets or patterns. We have therefore developed an instance-based approach to model biological shapes within a shape space built upon diffeomorphic measurement. We also designed a recursive interpolation algorithm to probabilistically synthesize new shape instances using the shape space model and the original instances. The method is quite generalizable and therefore can be applied to most nuclear, cell and protein object shapes, in both 2D and 3D.

  7. Integration of Simulink Models with Component-based Software Models

    DEFF Research Database (Denmark)

    Marian, Nicolae; Top, Søren

    2008-01-01

    to be analyzed. One way of doing that is to integrate in wrapper files the model back into Simulink S-functions, and use its extensive simulation features, thus allowing an early exploration of the possible design choices over multiple disciplines. The paper describes a safe translation of a restricted set......Model based development aims to facilitate the development of embedded control systems by emphasizing the separation of the design level from the implementation level. Model based design involves the use of multiple models that represent different views of a system, having different semantics...... constructs and process flow, then software code is generated. A Simulink model is a representation of the design or implementation of a physical system that satisfies a set of requirements. A software component-based system aims to organize system architecture and behaviour as a means of computation...

  8. Base Flow Model Validation, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — The program focuses on turbulence modeling enhancements for predicting high-speed rocket base flows. A key component of the effort is the collection of high-fidelity...

  9. New global ICT-based business models

    DEFF Research Database (Denmark)

    Universities. The book continues by describing, analyzing and showing how NEWGIBM was implemented in SMEs in different industrial companies/networks. Based on this effort, the researchers try to describe and analyze the current context, experience of NEWGIBM and finally the emerging scenarios of NEWGIBM...... The NEWGIBM Cases Show? The Strategy Concept in Light of the Increased Importance of Innovative Business Models Successful Implementation of Global BM Innovation Globalisation Of ICT Based Business Models: Today And In 2020...

  10. A probabilistic graphical model based stochastic input model construction

    International Nuclear Information System (INIS)

    Wan, Jiang; Zabaras, Nicholas

    2014-01-01

    Model reduction techniques have been widely used in modeling of high-dimensional stochastic input in uncertainty quantification tasks. However, the probabilistic modeling of random variables projected into reduced-order spaces presents a number of computational challenges. Due to the curse of dimensionality, the underlying dependence relationships between these random variables are difficult to capture. In this work, a probabilistic graphical model based approach is employed to learn the dependence by running a number of conditional independence tests using observation data. Thus a probabilistic model of the joint PDF is obtained and the PDF is factorized into a set of conditional distributions based on the dependence structure of the variables. The estimation of the joint PDF from data is then transformed to estimating conditional distributions under reduced dimensions. To improve the computational efficiency, a polynomial chaos expansion is further applied to represent the random field in terms of a set of standard random variables. This technique is combined with both linear and nonlinear model reduction methods. Numerical examples are presented to demonstrate the accuracy and efficiency of the probabilistic graphical model based stochastic input models. - Highlights: • Data-driven stochastic input models without the assumption of independence of the reduced random variables. • The problem is transformed to a Bayesian network structure learning problem. • Examples are given in flows in random media

  11. Econophysics of agent-based models

    CERN Document Server

    Aoyama, Hideaki; Chakrabarti, Bikas; Chakraborti, Anirban; Ghosh, Asim

    2014-01-01

    The primary goal of this book is to present the research findings and conclusions of physicists, economists, mathematicians and financial engineers working in the field of "Econophysics" who have undertaken agent-based modelling, comparison with empirical studies and related investigations. Most standard economic models assume the existence of the representative agent, who is “perfectly rational” and applies the utility maximization principle when taking action. One reason for this is the desire to keep models mathematically tractable: no tools are available to economists for solving non-linear models of heterogeneous adaptive agents without explicit optimization. In contrast, multi-agent models, which originated from statistical physics considerations, allow us to go beyond the prototype theories of traditional economics involving the representative agent. This book is based on the Econophys-Kolkata VII Workshop, at which many such modelling efforts were presented. In the book, leading researchers in the...

  12. Springer handbook of model-based science

    CERN Document Server

    Bertolotti, Tommaso

    2017-01-01

    The handbook offers the first comprehensive reference guide to the interdisciplinary field of model-based reasoning. It highlights the role of models as mediators between theory and experimentation, and as educational devices, as well as their relevance in testing hypotheses and explanatory functions. The Springer Handbook merges philosophical, cognitive and epistemological perspectives on models with the more practical needs related to the application of this tool across various disciplines and practices. The result is a unique, reliable source of information that guides readers toward an understanding of different aspects of model-based science, such as the theoretical and cognitive nature of models, as well as their practical and logical aspects. The inferential role of models in hypothetical reasoning, abduction and creativity once they are constructed, adopted, and manipulated for different scientific and technological purposes is also discussed. Written by a group of internationally renowned experts in ...

  13. Exploring model-based target discrimination metrics

    Science.gov (United States)

    Witus, Gary; Weathersby, Marshall

    2004-08-01

    Visual target discrimination has occurred when the observer can say "I see a target THERE!" and can designate the target location. Target discrimination occurs when a perceived shape is sufficiently similar one or more of the instances the observer has been trained on. Marr defined vision as "knowing what is where by seeing." Knowing "what" requires prior knowledge. Target discrimination requires model-based visual processing. Model-based signature metrics attempt to answer the question "to what extent does the target in the image resemble a training image?" Model-based signature metrics attempt to represent the effects of high-level top-down visual cognition, in addition to low-level bottom-up effects. Recent advances in realistic 3D target rendering and computer-vision object recognition have made model-based signature metrics more practical. The human visual system almost certainly does NOT use the same processing algorithms as computer vision object recognition, but some processing elements and the overall effects are similar. It remains to be determined whether model-based metrics explain the variance in human performance. The purpose of this paper is to explain and illustrate the model-based approach to signature metrics.

  14. Rule-based Modelling and Tunable Resolution

    Directory of Open Access Journals (Sweden)

    Russ Harmer

    2009-11-01

    Full Text Available We investigate the use of an extension of rule-based modelling for cellular signalling to create a structured space of model variants. This enables the incremental development of rule sets that start from simple mechanisms and which, by a gradual increase in agent and rule resolution, evolve into more detailed descriptions.

  15. Model-based testing for software safety

    NARCIS (Netherlands)

    Gurbuz, Havva Gulay; Tekinerdogan, Bedir

    2017-01-01

    Testing safety-critical systems is crucial since a failure or malfunction may result in death or serious injuries to people, equipment, or environment. An important challenge in testing is the derivation of test cases that can identify the potential faults. Model-based testing adopts models of a

  16. Approximation Algorithms for Model-Based Diagnosis

    NARCIS (Netherlands)

    Feldman, A.B.

    2010-01-01

    Model-based diagnosis is an area of abductive inference that uses a system model, together with observations about system behavior, to isolate sets of faulty components (diagnoses) that explain the observed behavior, according to some minimality criterion. This thesis presents greedy approximation

  17. Agent-based modelling of cholera diffusion

    NARCIS (Netherlands)

    Augustijn-Beckers, Petronella; Doldersum, Tom; Useya, Juliana; Augustijn, Dionysius C.M.

    2016-01-01

    This paper introduces a spatially explicit agent-based simulation model for micro-scale cholera diffusion. The model simulates both an environmental reservoir of naturally occurring V.cholerae bacteria and hyperinfectious V. cholerae. Objective of the research is to test if runoff from open refuse

  18. Analyzing the performance of PROSPECT model inversion based on different spectral information for leaf biochemical properties retrieval

    Science.gov (United States)

    Sun, Jia; Shi, Shuo; Yang, Jian; Du, Lin; Gong, Wei; Chen, Biwu; Song, Shalei

    2018-01-01

    Leaf biochemical constituents provide useful information about major ecological processes. As a fast and nondestructive method, remote sensing techniques are critical to reflect leaf biochemistry via models. PROSPECT model has been widely applied in retrieving leaf traits by providing hemispherical reflectance and transmittance. However, the process of measuring both reflectance and transmittance can be time-consuming and laborious. Contrary to use reflectance spectrum alone in PROSPECT model inversion, which has been adopted by many researchers, this study proposes to use transmission spectrum alone, with the increasing availability of the latter through various remote sensing techniques. Then we analyzed the performance of PROSPECT model inversion with (1) only transmission spectrum, (2) only reflectance and (3) both reflectance and transmittance, using synthetic datasets (with varying levels of random noise and systematic noise) and two experimental datasets (LOPEX and ANGERS). The results show that (1) PROSPECT-5 model inversion based solely on transmission spectrum is viable with results generally better than that based solely on reflectance spectrum; (2) leaf dry matter can be better estimated using only transmittance or reflectance than with both reflectance and transmittance spectra.

  19. Gradient based filtering of digital elevation models

    DEFF Research Database (Denmark)

    Knudsen, Thomas; Andersen, Rune Carbuhn

    We present a filtering method for digital terrain models (DTMs). The method is based on mathematical morphological filtering within gradient (slope) defined domains. The intention with the filtering procedure is to improbé the cartographic quality of height contours generated from a DTM based on ...

  20. Accept & Reject Statement-Based Uncertainty Models

    NARCIS (Netherlands)

    E. Quaeghebeur (Erik); G. de Cooman; F. Hermans (Felienne)

    2015-01-01

    textabstractWe develop a framework for modelling and reasoning with uncertainty based on accept and reject statements about gambles. It generalises the frameworks found in the literature based on statements of acceptability, desirability, or favourability and clarifies their relative position. Next

  1. Information modelling and knowledge bases XXV

    CERN Document Server

    Tokuda, T; Jaakkola, H; Yoshida, N

    2014-01-01

    Because of our ever increasing use of and reliance on technology and information systems, information modelling and knowledge bases continue to be important topics in those academic communities concerned with data handling and computer science. As the information itself becomes more complex, so do the levels of abstraction and the databases themselves. This book is part of the series Information Modelling and Knowledge Bases, which concentrates on a variety of themes in the important domains of conceptual modeling, design and specification of information systems, multimedia information modelin

  2. Néron Models and Base Change

    DEFF Research Database (Denmark)

    Halle, Lars Halvard; Nicaise, Johannes

    Presenting the first systematic treatment of the behavior of Néron models under ramified base change, this book can be read as an introduction to various subtle invariants and constructions related to Néron models of semi-abelian varieties, motivated by concrete research problems and complemented...... on Néron component groups, Edixhoven’s filtration and the base change conductor of Chai and Yu, and we study these invariants using various techniques such as models of curves, sheaves on Grothendieck sites and non-archimedean uniformization. We then apply our results to the study of motivic zeta functions...

  3. Energy based prediction models for building acoustics

    DEFF Research Database (Denmark)

    Brunskog, Jonas

    2012-01-01

    In order to reach robust and simplified yet accurate prediction models, energy based principle are commonly used in many fields of acoustics, especially in building acoustics. This includes simple energy flow models, the framework of statistical energy analysis (SEA) as well as more elaborated...... principles as, e.g., wave intensity analysis (WIA). The European standards for building acoustic predictions, the EN 12354 series, are based on energy flow and SEA principles. In the present paper, different energy based prediction models are discussed and critically reviewed. Special attention is placed...... on underlying basic assumptions, such as diffuse fields, high modal overlap, resonant field being dominant, etc., and the consequences of these in terms of limitations in the theory and in the practical use of the models....

  4. Multi-Domain Modeling Based on Modelica

    Directory of Open Access Journals (Sweden)

    Liu Jun

    2016-01-01

    Full Text Available With the application of simulation technology in large-scale and multi-field problems, multi-domain unified modeling become an effective way to solve these problems. This paper introduces several basic methods and advantages of the multidisciplinary model, and focuses on the simulation based on Modelica language. The Modelica/Mworks is a newly developed simulation software with features of an object-oriented and non-casual language for modeling of the large, multi-domain system, which makes the model easier to grasp, develop and maintain.It This article shows the single degree of freedom mechanical vibration system based on Modelica language special connection mechanism in Mworks. This method that multi-domain modeling has simple and feasible, high reusability. it closer to the physical system, and many other advantages.

  5. Pitted keratolysis – a frequently misdiagnosed, mild, infectious disorder of soles

    Directory of Open Access Journals (Sweden)

    Zuzanna Lewicka-Potocka

    2016-05-01

    Full Text Available Introduction . Pitted keratolysis (PK is a mild infectious skin disorder caused by Corynebacterium spp., Kytococcus sedentarius or Dermatophilus congolensis . These bacteria produce enzymes that digest keratin, causing superficial lesions in the plantar surface. The disease is predominantly observed in young men. Objective . Pitted keratolysis despite the characteristic presentation of skin lesions is often misdiagnosed. In this article we aimed to remind readers of its clinical aspects and treatment by presenting a typical PK case. Case report. A 35-year-old man was admitted to the dermatological clinic due to skin lesions on both soles. In the physical examination we found multiple crateriform pits, associated with hyperhidrosis and malodour diagnosed as PK. Remission of lesions was observed after treatment with oral erythromycin. Conclusions . The differential diagnosis of plantar skin lesions should include PK. Due to typical clinical manifestation the diagnosis is based on physical examination.

  6. Ultrasound-guided greater auricular nerve block as sole anesthetic for ear surgery

    Directory of Open Access Journals (Sweden)

    Michael K. Ritchie

    2016-05-01

    Full Text Available A greater auricular nerve (GAN block was used as the sole anesthetic for facial surgery in an 80-year-old male patient with multiple comorbidities which would have made general anesthesia challenging. The GAN provides sensation to the ear, mastoid process, parotid gland, and angle of the mandible. In addition to anesthesia for operating room surgery, the GAN block can be used for outpatient or emergency department procedures without the need for a separate anesthesia team. Although this nerve block has been performed using landmark-based techniques, the ultrasoundguided version offers several potential advantages. These advantages include increased reliability of the nerve block, as well as prevention of inadvertent vascular puncture or blockade of the phrenic nerve, brachial plexus, or deep cervical plexus. The increasing access to ultrasound technology for medical care providers outside the operating room makes this ultrasound guided block an increasingly viable alternative.

  7. Identification of walking human model using agent-based modelling

    Science.gov (United States)

    Shahabpoor, Erfan; Pavic, Aleksandar; Racic, Vitomir

    2018-03-01

    The interaction of walking people with large vibrating structures, such as footbridges and floors, in the vertical direction is an important yet challenging phenomenon to describe mathematically. Several different models have been proposed in the literature to simulate interaction of stationary people with vibrating structures. However, the research on moving (walking) human models, explicitly identified for vibration serviceability assessment of civil structures, is still sparse. In this study, the results of a comprehensive set of FRF-based modal tests were used, in which, over a hundred test subjects walked in different group sizes and walking patterns on a test structure. An agent-based model was used to simulate discrete traffic-structure interactions. The occupied structure modal parameters found in tests were used to identify the parameters of the walking individual's single-degree-of-freedom (SDOF) mass-spring-damper model using 'reverse engineering' methodology. The analysis of the results suggested that the normal distribution with the average of μ = 2.85Hz and standard deviation of σ = 0.34Hz can describe human SDOF model natural frequency. Similarly, the normal distribution with μ = 0.295 and σ = 0.047 can describe the human model damping ratio. Compared to the previous studies, the agent-based modelling methodology proposed in this paper offers significant flexibility in simulating multi-pedestrian walking traffics, external forces and simulating different mechanisms of human-structure and human-environment interaction at the same time.

  8. A model evaluation checklist for process-based environmental models

    Science.gov (United States)

    Jackson-Blake, Leah

    2015-04-01

    the conceptual model on which it is based. In this study, a number of model structural shortcomings were identified, such as a lack of dissolved phosphorus transport via infiltration excess overland flow, potential discrepancies in the particulate phosphorus simulation and a lack of spatial granularity. (4) Conceptual challenges, as conceptual models on which predictive models are built are often outdated, having not kept up with new insights from monitoring and experiments. For example, soil solution dissolved phosphorus concentration in INCA-P is determined by the Freundlich adsorption isotherm, which could potentially be replaced using more recently-developed adsorption models that take additional soil properties into account. This checklist could be used to assist in identifying why model performance may be poor or unreliable. By providing a model evaluation framework, it could help prioritise which areas should be targeted to improve model performance or model credibility, whether that be through using alternative calibration techniques and statistics, improved data collection, improving or simplifying the model structure or updating the model to better represent current understanding of catchment processes.

  9. Development of Ensemble Model Based Water Demand Forecasting Model

    Science.gov (United States)

    Kwon, Hyun-Han; So, Byung-Jin; Kim, Seong-Hyeon; Kim, Byung-Seop

    2014-05-01

    In recent years, Smart Water Grid (SWG) concept has globally emerged over the last decade and also gained significant recognition in South Korea. Especially, there has been growing interest in water demand forecast and optimal pump operation and this has led to various studies regarding energy saving and improvement of water supply reliability. Existing water demand forecasting models are categorized into two groups in view of modeling and predicting their behavior in time series. One is to consider embedded patterns such as seasonality, periodicity and trends, and the other one is an autoregressive model that is using short memory Markovian processes (Emmanuel et al., 2012). The main disadvantage of the abovementioned model is that there is a limit to predictability of water demands of about sub-daily scale because the system is nonlinear. In this regard, this study aims to develop a nonlinear ensemble model for hourly water demand forecasting which allow us to estimate uncertainties across different model classes. The proposed model is consist of two parts. One is a multi-model scheme that is based on combination of independent prediction model. The other one is a cross validation scheme named Bagging approach introduced by Brieman (1996) to derive weighting factors corresponding to individual models. Individual forecasting models that used in this study are linear regression analysis model, polynomial regression, multivariate adaptive regression splines(MARS), SVM(support vector machine). The concepts are demonstrated through application to observed from water plant at several locations in the South Korea. Keywords: water demand, non-linear model, the ensemble forecasting model, uncertainty. Acknowledgements This subject is supported by Korea Ministry of Environment as "Projects for Developing Eco-Innovation Technologies (GT-11-G-02-001-6)

  10. A Nursing Practice Model Based on Christ: The Agape Model.

    Science.gov (United States)

    Eckerd, Nancy

    2017-06-07

    Nine out of 10 American adults believe Jesus was a real person, and almost two-thirds have made a commitment to Jesus Christ. Research further supports that spiritual beliefs and religious practices influence overall health and well-being. Christian nurses need a practice model that helps them serve as kingdom nurses. This article introduces the Agape Model, based on the agape love and characteristics of Christ, upon which Christian nurses may align their practice to provide Christ-centered care.

  11. SLS Navigation Model-Based Design Approach

    Science.gov (United States)

    Oliver, T. Emerson; Anzalone, Evan; Geohagan, Kevin; Bernard, Bill; Park, Thomas

    2018-01-01

    The SLS Program chose to implement a Model-based Design and Model-based Requirements approach for managing component design information and system requirements. This approach differs from previous large-scale design efforts at Marshall Space Flight Center where design documentation alone conveyed information required for vehicle design and analysis and where extensive requirements sets were used to scope and constrain the design. The SLS Navigation Team has been responsible for the Program-controlled Design Math Models (DMMs) which describe and represent the performance of the Inertial Navigation System (INS) and the Rate Gyro Assemblies (RGAs) used by Guidance, Navigation, and Controls (GN&C). The SLS Navigation Team is also responsible for the navigation algorithms. The navigation algorithms are delivered for implementation on the flight hardware as a DMM. For the SLS Block 1-B design, the additional GPS Receiver hardware is managed as a DMM at the vehicle design level. This paper provides a discussion of the processes and methods used to engineer, design, and coordinate engineering trades and performance assessments using SLS practices as applied to the GN&C system, with a particular focus on the Navigation components. These include composing system requirements, requirements verification, model development, model verification and validation, and modeling and analysis approaches. The Model-based Design and Requirements approach does not reduce the effort associated with the design process versus previous processes used at Marshall Space Flight Center. Instead, the approach takes advantage of overlap between the requirements development and management process, and the design and analysis process by efficiently combining the control (i.e. the requirement) and the design mechanisms. The design mechanism is the representation of the component behavior and performance in design and analysis tools. The focus in the early design process shifts from the development and

  12. 78 FR 19261 - Safe Drinking Water Act Sole Source Aquifer Program; Designation of Bainbridge Island, Washington...

    Science.gov (United States)

    2013-03-29

    ... principle source of drinking water for the citizens of Bainbridge Island and that this aquifer system, if... designation. II. Basis for Determination EPA defines a sole or principle source aquifer as an aquifer or... ENVIRONMENTAL PROTECTION AGENCY Safe Drinking Water Act Sole Source Aquifer Program; Designation...

  13. 75 FR 53269 - Federal Acquisition Regulation; Tribal Consultation; Justification and Approval of Sole-Source 8...

    Science.gov (United States)

    2010-08-31

    ... and approval of sole-source contracts over $20 million under the 8(a) small business development... valuable component of its deliberations in preparing to implement this law, which includes contracting with... Regulation; Tribal Consultation; Justification and Approval of Sole-Source 8(a) Contracts AGENCIES...

  14. Variation in behaviour and growth of common sole : genetic and environmental influences

    NARCIS (Netherlands)

    Mas Muñoz, J.

    2013-01-01

    Common sole (Solea solea) has a high potential for commercial aquaculture because of its consumer popularity and high market values in Europe. However, a major economic constraint for the culture of sole is its slow and variable growth. The aim of this thesis was to investigate: 1) the importance of

  15. Variation in behaviour and growth of common sole : genetic and environmental influences

    NARCIS (Netherlands)

    Mas Muñoz, J.

    2013-01-01

    Common sole (Solea solea) has a high potential for commercial aquaculture because of its consumer popularity and high market values in Europe. However, a major economic constraint for the culture of sole is its slow and variable growth. The aim of this thesis was to investigate: 1) the

  16. 26 CFR 1.1081-3 - Exchanges of stock or securities solely for stock or securities.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 11 2010-04-01 2010-04-01 true Exchanges of stock or securities solely for stock or securities. 1.1081-3 Section 1.1081-3 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF... § 1.1081-3 Exchanges of stock or securities solely for stock or securities. The exchange, without the...

  17. Néron Models and Base Change

    DEFF Research Database (Denmark)

    Halle, Lars Halvard; Nicaise, Johannes

    Presenting the first systematic treatment of the behavior of Néron models under ramified base change, this book can be read as an introduction to various subtle invariants and constructions related to Néron models of semi-abelian varieties, motivated by concrete research problems and complemented...... with explicit examples. Néron models of abelian and semi-abelian varieties have become an indispensable tool in algebraic and arithmetic geometry since Néron introduced them in his seminal 1964 paper. Applications range from the theory of heights in Diophantine geometry to Hodge theory. We focus specifically...... on Néron component groups, Edixhoven’s filtration and the base change conductor of Chai and Yu, and we study these invariants using various techniques such as models of curves, sheaves on Grothendieck sites and non-archimedean uniformization. We then apply our results to the study of motivic zeta functions...

  18. A Multiagent Based Model for Tactical Planning

    Science.gov (United States)

    2002-10-01

    Pub. Co. 1985. [10] Castillo, J.M. Aproximación mediante procedimientos de Inteligencia Artificial al planeamiento táctico. Doctoral Thesis...been developed under the same conceptual model and using similar Artificial Intelligence Tools. We use four different stimulus/response agents in...The conceptual model is built on base of the Agents theory. To implement the different agents we have used Artificial Intelligence techniques such

  19. Model-Based Motion Tracking of Infants

    DEFF Research Database (Denmark)

    Olsen, Mikkel Damgaard; Herskind, Anna; Nielsen, Jens Bo

    2014-01-01

    Even though motion tracking is a widely used technique to analyze and measure human movements, only a few studies focus on motion tracking of infants. In recent years, a number of studies have emerged focusing on analyzing the motion pattern of infants, using computer vision. Most of these studie...... that resembles the body surface of an infant, where the model is based on simple geometric shapes and a hierarchical skeleton model....

  20. Quality Model Based on Cots Quality Attributes

    OpenAIRE

    Jawad Alkhateeb; Khaled Musa

    2013-01-01

    The quality of software is essential to corporations in making their commercial software. Good or poorquality to software plays an important role to some systems such as embedded systems, real-time systems,and control systems that play an important aspect in human life. Software products or commercial off theshelf software are usually programmed based on a software quality model. In the software engineeringfield, each quality model contains a set of attributes or characteristics that drives i...

  1. Evolutionary modeling-based approach for model errors correction

    Directory of Open Access Journals (Sweden)

    S. Q. Wan

    2012-08-01

    Full Text Available The inverse problem of using the information of historical data to estimate model errors is one of the science frontier research topics. In this study, we investigate such a problem using the classic Lorenz (1963 equation as a prediction model and the Lorenz equation with a periodic evolutionary function as an accurate representation of reality to generate "observational data."

    On the basis of the intelligent features of evolutionary modeling (EM, including self-organization, self-adaptive and self-learning, the dynamic information contained in the historical data can be identified and extracted by computer automatically. Thereby, a new approach is proposed to estimate model errors based on EM in the present paper. Numerical tests demonstrate the ability of the new approach to correct model structural errors. In fact, it can actualize the combination of the statistics and dynamics to certain extent.

  2. Image-Based Multiresolution Implicit Object Modeling

    Directory of Open Access Journals (Sweden)

    Sarti Augusto

    2002-01-01

    Full Text Available We discuss two image-based 3D modeling methods based on a multiresolution evolution of a volumetric function′s level set. In the former method, the role of the level set implosion is to fuse ("sew" and "stitch" together several partial reconstructions (depth maps into a closed model. In the later, the level set′s implosion is steered directly by the texture mismatch between views. Both solutions share the characteristic of operating in an adaptive multiresolution fashion, in order to boost up computational efficiency and robustness.

  3. Model-based testing for embedded systems

    CERN Document Server

    Zander, Justyna; Mosterman, Pieter J

    2011-01-01

    What the experts have to say about Model-Based Testing for Embedded Systems: "This book is exactly what is needed at the exact right time in this fast-growing area. From its beginnings over 10 years ago of deriving tests from UML statecharts, model-based testing has matured into a topic with both breadth and depth. Testing embedded systems is a natural application of MBT, and this book hits the nail exactly on the head. Numerous topics are presented clearly, thoroughly, and concisely in this cutting-edge book. The authors are world-class leading experts in this area and teach us well-used

  4. Model Based Control of Reefer Container Systems

    DEFF Research Database (Denmark)

    Sørensen, Kresten Kjær

    This thesis is concerned with the development of model based control for the Star Cool refrigerated container (reefer) with the objective of reducing energy consumption. This project has been carried out under the Danish Industrial PhD programme and has been financed by Lodam together with the Da......This thesis is concerned with the development of model based control for the Star Cool refrigerated container (reefer) with the objective of reducing energy consumption. This project has been carried out under the Danish Industrial PhD programme and has been financed by Lodam together...

  5. Sole ulcers in dairy cattle associations with season, cow characteristics, disease, and production

    DEFF Research Database (Denmark)

    Enevoldsen, Carsten; Gröhn, Y.T.; Thysen, Iver

    1991-01-01

    foot or more than one foot occurred in 20.0 and 29.7% of cows in lactation 1 and in 23.5 and 24.7% of cows in lactations 2 to 9. The analysis revealed several complicated interactions. Trimming or calving in summer to fall was strongly associated with sole ulcer. Trimming later than 1 to 2 mo after...... calving was positively associated with sole ulcer depending on milk yield, body weight, or season of calving. If lactation 1 cows were treated for disease (limb, metabolic, digestive, or severe reproductive disorders), sole ulcer in more than one foot occurred earlier in lactation. Milk yield in early......Epidemiological associations, expressed as odds ratios between variables obtained from dairy cow records and sole ulcer occurrence at claw trimmings were estimated with logistic regression analysis on data from 2204 and 1124 cows in lactation 1 and lactations 2 to 9, respectively. Sole ulcer in one...

  6. The Influence of Outdoor Shoe Sole Stiffness on the Metatarsophalangeal Joint Kinematics When Walking and Running in Different Conditions

    Directory of Open Access Journals (Sweden)

    Paolo Mistretta

    2018-02-01

    Full Text Available Understanding the action of the metatarsophalangeal joint (MTP is fundamental to improving the design process of a new outdoor shoe. Coming from the stated consideration, the aim of this research is to study the influence of shoe sole stiffness and terrain slope on the MTP joint angle of subjects walking in different conditions. To pursue this intent, different data collection sessions have been carried out in-vitro and in-vivo, indoor and outdoor. Two different approaches have been used to collect gait kinematics: an IMU (Inertial Measurement Unit based system for the first campaign of tests, and a 2D video analysis for the second. Major findings showed a linear correlation between shoe sole stiffness and peak MTP joint angle during gait, as well as consistency in the value of the slope of the linear regression curves corresponding to the different conditions examined.

  7. Designing Network-based Business Model Ontology

    DEFF Research Database (Denmark)

    Hashemi Nekoo, Ali Reza; Ashourizadeh, Shayegheh; Zarei, Behrouz

    2015-01-01

    is going to propose e-business model ontology from the network point of view and its application in real world. The suggested ontology for network-based businesses is composed of individuals` characteristics and what kind of resources they own. also, their connections and pre-conceptions of connections...... such as shared-mental model and trust. However, it mostly covers previous business model elements. To confirm the applicability of this ontology, it has been implemented in business angel network and showed how it works....

  8. Model Predictive Control based on Finite Impulse Response Models

    DEFF Research Database (Denmark)

    Prasath, Guru; Jørgensen, John Bagterp

    2008-01-01

    We develop a regularized l2 finite impulse response (FIR) predictive controller with input and input-rate constraints. Feedback is based on a simple constant output disturbance filter. The performance of the predictive controller in the face of plant-model mismatch is investigated by simulations ...

  9. Incident Duration Modeling Using Flexible Parametric Hazard-Based Models

    Directory of Open Access Journals (Sweden)

    Ruimin Li

    2014-01-01

    Full Text Available Assessing and prioritizing the duration time and effects of traffic incidents on major roads present significant challenges for road network managers. This study examines the effect of numerous factors associated with various types of incidents on their duration and proposes an incident duration prediction model. Several parametric accelerated failure time hazard-based models were examined, including Weibull, log-logistic, log-normal, and generalized gamma, as well as all models with gamma heterogeneity and flexible parametric hazard-based models with freedom ranging from one to ten, by analyzing a traffic incident dataset obtained from the Incident Reporting and Dispatching System in Beijing in 2008. Results show that different factors significantly affect different incident time phases, whose best distributions were diverse. Given the best hazard-based models of each incident time phase, the prediction result can be reasonable for most incidents. The results of this study can aid traffic incident management agencies not only in implementing strategies that would reduce incident duration, and thus reduce congestion, secondary incidents, and the associated human and economic losses, but also in effectively predicting incident duration time.

  10. Folic acid supplementation is not the sole factor in determining ...

    African Journals Online (AJOL)

    user user

    2012-07-10

    Jul 10, 2012 ... NTD studies conducted in Malaysia report a prevalence ranging from 0.79 to 1.29 per 1000 live births based on NTD ... addition, intervention studies concluded that daily consumption of 400 µg of folic acid effectively reduced NTD risk ... Furthermore, neurogenic bowel syndrome, which accompanies NTDs ...

  11. Knowledge-Based Environmental Context Modeling

    Science.gov (United States)

    Pukite, P. R.; Challou, D. J.

    2017-12-01

    As we move from the oil-age to an energy infrastructure based on renewables, the need arises for new educational tools to support the analysis of geophysical phenomena and their behavior and properties. Our objective is to present models of these phenomena to make them amenable for incorporation into more comprehensive analysis contexts. Starting at the level of a college-level computer science course, the intent is to keep the models tractable and therefore practical for student use. Based on research performed via an open-source investigation managed by DARPA and funded by the Department of Interior [1], we have adapted a variety of physics-based environmental models for a computer-science curriculum. The original research described a semantic web architecture based on patterns and logical archetypal building-blocks (see figure) well suited for a comprehensive environmental modeling framework. The patterns span a range of features that cover specific land, atmospheric and aquatic domains intended for engineering modeling within a virtual environment. The modeling engine contained within the server relied on knowledge-based inferencing capable of supporting formal terminology (through NASA JPL's Semantic Web for Earth and Environmental Technology (SWEET) ontology and a domain-specific language) and levels of abstraction via integrated reasoning modules. One of the key goals of the research was to simplify models that were ordinarily computationally intensive to keep them lightweight enough for interactive or virtual environment contexts. The breadth of the elements incorporated is well-suited for learning as the trend toward ontologies and applying semantic information is vital for advancing an open knowledge infrastructure. As examples of modeling, we have covered such geophysics topics as fossil-fuel depletion, wind statistics, tidal analysis, and terrain modeling, among others. Techniques from the world of computer science will be necessary to promote efficient

  12. Risk-based modelling of surface water quality: a case study of the Charles River, Massachusetts

    Science.gov (United States)

    McIntyre, Neil R.; Wagener, Thorsten; Wheater, Howard S.; Chapra, Steven C.

    2003-04-01

    A model of phytoplankton, dissolved oxygen and nutrients is presented and applied to the Charles River, Massachusetts within a framework of Monte Carlo simulation. The model parameters are conditioned using data from eight sampling stations along a 40 km stretch of the Charles River, during a (supposed) steady-state period in the summer of 1996, and the conditioned model is evaluated using data from later in the same year. Regional multi-objective sensitivity analysis is used to identify the parameters and pollution sources most affecting the various model outputs under the conditions observed during that summer. The effects of Monte Carlo sampling error are included in this analysis, and the observations which have least contributed to model conditioning are indicated. It is shown that the sensitivity analysis can be used to speculate about the factors responsible for undesirable levels of eutrophication, and to speculate about the risk of failure of nutrient reduction interventions at a number of strategic control sections. The analysis indicates that phosphorus stripping at the CRPCD wastewater treatment plant on the Charles River would be a high-risk intervention, especially for controlling eutrophication at the control sections further downstream. However, as the risk reflects the perceived scope for model error, it can only be recommended that more resources are invested in data collection and model evaluation. Furthermore, as the risk is based solely on water quality criteria, rather than broader environmental and economic objectives, the results need to be supported by detailed and extensive knowledge of the Charles River problem.

  13. Atomic Action Refinement in Model Based Testing

    NARCIS (Netherlands)

    van der Bijl, H.M.; Rensink, Arend; Tretmans, G.J.

    2007-01-01

    In model based testing (MBT) test cases are derived from a specification of the system that we want to test. In general the specification is more abstract than the implementation. This may result in 1) test cases that are not executable, because their actions are too abstract (the implementation

  14. Prototype-based models in machine learning

    NARCIS (Netherlands)

    Biehl, Michael; Hammer, Barbara; Villmann, Thomas

    2016-01-01

    An overview is given of prototype-based models in machine learning. In this framework, observations, i.e., data, are stored in terms of typical representatives. Together with a suitable measure of similarity, the systems can be employed in the context of unsupervised and supervised analysis of

  15. Model based development of engine control algorithms

    NARCIS (Netherlands)

    Dekker, H.J.; Sturm, W.L.

    1996-01-01

    Model based development of engine control systems has several advantages. The development time and costs are strongly reduced because much of the development and optimization work is carried out by simulating both engine and control system. After optimizing the control algorithm it can be executed

  16. Modelling Web-Based Instructional Systems

    NARCIS (Netherlands)

    Retalis, Symeon; Avgeriou, Paris

    2002-01-01

    The size and complexity of modern instructional systems, which are based on the World Wide Web, bring about great intricacy in their crafting, as there is not enough knowledge or experience in this field. This imposes the use of new instructional design models in order to achieve risk-mitigation,

  17. Ligand based pharmacophore modelling of anticancer histone ...

    African Journals Online (AJOL)

    like myocardium damage and bone marrow depression even leading to cell death have been observed in the treatment of caner cells using HDAC inhibitors. The discovery and development of type-specific HDAC inhibitors is of both research and clinical interests. Ligand based pharmacophore modelling is playing a key ...

  18. Model-based auditing using REA

    NARCIS (Netherlands)

    Weigand, H.; Elsas, P.

    2012-01-01

    The recent financial crisis has renewed interest in the value of the owner-ordered auditing tradition that starts from society's long-term interest rather than management interest. This tradition uses a model-based auditing approach in which control requirements are derived in a principled way. A

  19. Dynamic Ligand Based Pharmacophore Modeling and Virtual ...

    Indian Academy of Sciences (India)

    user

    ChEMBL-HIV https://www.ebi.ac.uk/chembl/index.php/assay/results (ChEMBL Bioassay was searched with the key word “Human. Immunodefficiency virus”, display bioactivity option was chosen and then “Download All Bioactivity Data” was ... Ligand based pharmacophore models generated from the crystal structure and.

  20. Agent Based Modeling as an Educational Tool

    Science.gov (United States)

    Fuller, J. H.; Johnson, R.; Castillo, V.

    2012-12-01

    Motivation is a key element in high school education. One way to improve motivation and provide content, while helping address critical thinking and problem solving skills, is to have students build and study agent based models in the classroom. This activity visually connects concepts with their applied mathematical representation. "Engaging students in constructing models may provide a bridge between frequently disconnected conceptual and mathematical forms of knowledge." (Levy and Wilensky, 2011) We wanted to discover the feasibility of implementing a model based curriculum in the classroom given current and anticipated core and content standards.; Simulation using California GIS data ; Simulation of high school student lunch popularity using aerial photograph on top of terrain value map.

  1. Model-Based Angular Scan Error Correction of an Electrothermally-Actuated MEMS Mirror.

    Science.gov (United States)

    Zhang, Hao; Xu, Dacheng; Zhang, Xiaoyang; Chen, Qiao; Xie, Huikai; Li, Suiqiong

    2015-12-10

    In this paper, the actuation behavior of a two-axis electrothermal MEMS (Microelectromechanical Systems) mirror typically used in miniature optical scanning probes and optical switches is investigated. The MEMS mirror consists of four thermal bimorph actuators symmetrically located at the four sides of a central mirror plate. Experiments show that an actuation characteristics difference of as much as 4.0% exists among the four actuators due to process variations, which leads to an average angular scan error of 0.03°. A mathematical model between the actuator input voltage and the mirror-plate position has been developed to predict the actuation behavior of the mirror. It is a four-input, four-output model that takes into account the thermal-mechanical coupling and the differences among the four actuators; the vertical positions of the ends of the four actuators are also monitored. Based on this model, an open-loop control method is established to achieve accurate angular scanning. This model-based open loop control has been experimentally verified and is useful for the accurate control of the mirror. With this control method, the precise actuation of the mirror solely depends on the model prediction and does not need the real-time mirror position monitoring and feedback, greatly simplifying the MEMS control system.

  2. PARTICIPATION BASED MODEL OF SHIP CREW MANAGEMENT

    Directory of Open Access Journals (Sweden)

    Toni Bielić

    2014-10-01

    Full Text Available 800x600 This paper analyse the participation - based model on board the ship as possibly optimal leadership model existing in the shipping industry with accent on decision - making process. In the paper authors have tried to define master’s behaviour model and management style identifying drawbacks and disadvantages of vertical, pyramidal organization with master on the top. Paper describes efficiency of decision making within team organization and optimization of a ship’s organisation by introducing teamwork on board the ship. Three examples of the ship’s accidents are studied and evaluated through “Leader - participation” model. The model of participation based management as a model of the teamwork has been applied in studying the cause - and - effect of accidents with the critical review of the communication and managing the human resources on a ship. The results have showed that the cause of all three accidents is the autocratic behaviour of the leaders and lack of communication within teams. Normal 0 21 false false false HR X-NONE X-NONE MicrosoftInternetExplorer4

  3. From Creatures of Habit to Goal-Directed Learners: Tracking the Developmental Emergence of Model-Based Reinforcement Learning.

    Science.gov (United States)

    Decker, Johannes H; Otto, A Ross; Daw, Nathaniel D; Hartley, Catherine A

    2016-06-01

    Theoretical models distinguish two decision-making strategies that have been formalized in reinforcement-learning theory. A model-based strategy leverages a cognitive model of potential actions and their consequences to make goal-directed choices, whereas a model-free strategy evaluates actions based solely on their reward history. Research in adults has begun to elucidate the psychological mechanisms and neural substrates underlying these learning processes and factors that influence their relative recruitment. However, the developmental trajectory of these evaluative strategies has not been well characterized. In this study, children, adolescents, and adults performed a sequential reinforcement-learning task that enabled estimation of model-based and model-free contributions to choice. Whereas a model-free strategy was apparent in choice behavior across all age groups, a model-based strategy was absent in children, became evident in adolescents, and strengthened in adults. These results suggest that recruitment of model-based valuation systems represents a critical cognitive component underlying the gradual maturation of goal-directed behavior. © The Author(s) 2016.

  4. Multiagent-Based Model For ESCM

    Directory of Open Access Journals (Sweden)

    Delia MARINCAS

    2011-01-01

    Full Text Available Web based applications for Supply Chain Management (SCM are now a necessity for every company in order to meet the increasing customer demands, to face the global competition and to make profit. Multiagent-based approach is appropriate for eSCM because it shows many of the characteristics a SCM system should have. For this reason, we have proposed a multiagent-based eSCM model which configures a virtual SC, automates the SC activities: selling, purchasing, manufacturing, planning, inventory, etc. This model will allow a better coordination of the supply chain network and will increase the effectiveness of Web and intel-ligent technologies employed in eSCM software.

  5. Modeling acquaintance networks based on balance theory

    Directory of Open Access Journals (Sweden)

    Vukašinović Vida

    2014-09-01

    Full Text Available An acquaintance network is a social structure made up of a set of actors and the ties between them. These ties change dynamically as a consequence of incessant interactions between the actors. In this paper we introduce a social network model called the Interaction-Based (IB model that involves well-known sociological principles. The connections between the actors and the strength of the connections are influenced by the continuous positive and negative interactions between the actors and, vice versa, the future interactions are more likely to happen between the actors that are connected with stronger ties. The model is also inspired by the social behavior of animal species, particularly that of ants in their colony. A model evaluation showed that the IB model turned out to be sparse. The model has a small diameter and an average path length that grows in proportion to the logarithm of the number of vertices. The clustering coefficient is relatively high, and its value stabilizes in larger networks. The degree distributions are slightly right-skewed. In the mature phase of the IB model, i.e., when the number of edges does not change significantly, most of the network properties do not change significantly either. The IB model was found to be the best of all the compared models in simulating the e-mail URV (University Rovira i Virgili of Tarragona network because the properties of the IB model more closely matched those of the e-mail URV network than the other models

  6. Multivariate statistical modelling based on generalized linear models

    CERN Document Server

    Fahrmeir, Ludwig

    1994-01-01

    This book is concerned with the use of generalized linear models for univariate and multivariate regression analysis. Its emphasis is to provide a detailed introductory survey of the subject based on the analysis of real data drawn from a variety of subjects including the biological sciences, economics, and the social sciences. Where possible, technical details and proofs are deferred to an appendix in order to provide an accessible account for non-experts. Topics covered include: models for multi-categorical responses, model checking, time series and longitudinal data, random effects models, and state-space models. Throughout, the authors have taken great pains to discuss the underlying theoretical ideas in ways that relate well to the data at hand. As a result, numerous researchers whose work relies on the use of these models will find this an invaluable account to have on their desks. "The basic aim of the authors is to bring together and review a large part of recent advances in statistical modelling of m...

  7. Satellite-based terrestrial production efficiency modeling

    Directory of Open Access Journals (Sweden)

    Obersteiner Michael

    2009-09-01

    Full Text Available Abstract Production efficiency models (PEMs are based on the theory of light use efficiency (LUE which states that a relatively constant relationship exists between photosynthetic carbon uptake and radiation receipt at the canopy level. Challenges remain however in the application of the PEM methodology to global net primary productivity (NPP monitoring. The objectives of this review are as follows: 1 to describe the general functioning of six PEMs (CASA; GLO-PEM; TURC; C-Fix; MOD17; and BEAMS identified in the literature; 2 to review each model to determine potential improvements to the general PEM methodology; 3 to review the related literature on satellite-based gross primary productivity (GPP and NPP modeling for additional possibilities for improvement; and 4 based on this review, propose items for coordinated research. This review noted a number of possibilities for improvement to the general PEM architecture - ranging from LUE to meteorological and satellite-based inputs. Current PEMs tend to treat the globe similarly in terms of physiological and meteorological factors, often ignoring unique regional aspects. Each of the existing PEMs has developed unique methods to estimate NPP and the combination of the most successful of these could lead to improvements. It may be beneficial to develop regional PEMs that can be combined under a global framework. The results of this review suggest the creation of a hybrid PEM could bring about a significant enhancement to the PEM methodology and thus terrestrial carbon flux modeling. Key items topping the PEM research agenda identified in this review include the following: LUE should not be assumed constant, but should vary by plant functional type (PFT or photosynthetic pathway; evidence is mounting that PEMs should consider incorporating diffuse radiation; continue to pursue relationships between satellite-derived variables and LUE, GPP and autotrophic respiration (Ra; there is an urgent need for

  8. Satellite-based terrestrial production efficiency modeling.

    Science.gov (United States)

    McCallum, Ian; Wagner, Wolfgang; Schmullius, Christiane; Shvidenko, Anatoly; Obersteiner, Michael; Fritz, Steffen; Nilsson, Sten

    2009-09-18

    Production efficiency models (PEMs) are based on the theory of light use efficiency (LUE) which states that a relatively constant relationship exists between photosynthetic carbon uptake and radiation receipt at the canopy level. Challenges remain however in the application of the PEM methodology to global net primary productivity (NPP) monitoring. The objectives of this review are as follows: 1) to describe the general functioning of six PEMs (CASA; GLO-PEM; TURC; C-Fix; MOD17; and BEAMS) identified in the literature; 2) to review each model to determine potential improvements to the general PEM methodology; 3) to review the related literature on satellite-based gross primary productivity (GPP) and NPP modeling for additional possibilities for improvement; and 4) based on this review, propose items for coordinated research.This review noted a number of possibilities for improvement to the general PEM architecture - ranging from LUE to meteorological and satellite-based inputs. Current PEMs tend to treat the globe similarly in terms of physiological and meteorological factors, often ignoring unique regional aspects. Each of the existing PEMs has developed unique methods to estimate NPP and the combination of the most successful of these could lead to improvements. It may be beneficial to develop regional PEMs that can be combined under a global framework. The results of this review suggest the creation of a hybrid PEM could bring about a significant enhancement to the PEM methodology and thus terrestrial carbon flux modeling.Key items topping the PEM research agenda identified in this review include the following: LUE should not be assumed constant, but should vary by plant functional type (PFT) or photosynthetic pathway; evidence is mounting that PEMs should consider incorporating diffuse radiation; continue to pursue relationships between satellite-derived variables and LUE, GPP and autotrophic respiration (Ra); there is an urgent need for satellite-based biomass

  9. Foot sole skin vibration perceptual thresholds are elevated in a standing posture compared to sitting.

    Science.gov (United States)

    Mildren, Robyn L; Strzalkowski, Nicholas D J; Bent, Leah R

    2016-01-01

    Foot sole sensitivity is commonly assessed while individuals are seated or prone; however the primary role of foot sole cutaneous feedback is for the control of upright stance and gait. The aim of this study was to compare vibration perceptual thresholds across the foot sole between sitting and standing postures. Vibration perceptual thresholds were measured in sitting and standing postures in 18 healthy participants (8 male) using a custom vibration device. Two foot sole locations (heels and metatarsals) were tested at four vibration frequencies (3, 15, 40, and 250Hz) selected to target different cutaneous afferent populations. At each frequency, perceptual thresholds across the foot sole were significantly higher in the standing posture compared to the sitting posture; this is indicative of lower sensitivity while standing. In addition, threshold differences between the heels and metatarsals for lower frequency vibratory stimuli were more pronounced while standing, with higher thresholds observed at the heels. Our results demonstrate that standing significantly alters sensitivity across the foot sole. Therefore, conducting perceptual tests at the foot sole during stance could potentially provide more direct information about the ability of cutaneous afferents to signal tactile information in a state where this feedback can contribute to postural control. Copyright © 2015 Elsevier B.V. All rights reserved.

  10. Electrochemistry-based Battery Modeling for Prognostics

    Science.gov (United States)

    Daigle, Matthew J.; Kulkarni, Chetan Shrikant

    2013-01-01

    Batteries are used in a wide variety of applications. In recent years, they have become popular as a source of power for electric vehicles such as cars, unmanned aerial vehicles, and commericial passenger aircraft. In such application domains, it becomes crucial to both monitor battery health and performance and to predict end of discharge (EOD) and end of useful life (EOL) events. To implement such technologies, it is crucial to understand how batteries work and to capture that knowledge in the form of models that can be used by monitoring, diagnosis, and prognosis algorithms. In this work, we develop electrochemistry-based models of lithium-ion batteries that capture the significant electrochemical processes, are computationally efficient, capture the effects of aging, and are of suitable accuracy for reliable EOD prediction in a variety of usage profiles. This paper reports on the progress of such a model, with results demonstrating the model validity and accurate EOD predictions.

  11. Mechanics model for actin-based motility.

    Science.gov (United States)

    Lin, Yuan

    2009-02-01

    We present here a mechanics model for the force generation by actin polymerization. The possible adhesions between the actin filaments and the load surface, as well as the nucleation and capping of filament tips, are included in this model on top of the well-known elastic Brownian ratchet formulation. A closed form solution is provided from which the force-velocity relationship, summarizing the mechanics of polymerization, can be drawn. Model predictions on the velocity of moving beads driven by actin polymerization are consistent with experiment observations. This model also seems capable of explaining the enhanced actin-based motility of Listeria monocytogenes and beads by the presence of Vasodilator-stimulated phosphoprotein, as observed in recent experiments.

  12. Effect of rocker-soled shoes on parameters of knee joint load in knee osteoarthritis.

    Science.gov (United States)

    Madden, Elizabeth G; Kean, Crystal O; Wrigley, Tim V; Bennell, Kim L; Hinman, Rana S

    2015-01-01

    This study evaluated the immediate effects of rocker-soled shoes on parameters of the knee adduction moment (KAM) and pain in individuals with knee osteoarthritis (OA). Three-dimensional gait analysis was performed on 30 individuals (mean (SD): age, 61 (7) yr; 15 (50%) male) with radiographic and symptomatic knee OA under three walking conditions in a randomized order: i) wearing rocker-soled shoes (Skechers Shape-ups), ii) wearing non-rocker-soled shoes (ASICS walking shoes), and iii) barefoot. Peak KAM and KAM angular impulse were measured as primary indicators of knee load distribution. Secondary measures included the knee flexion moment (KFM) and knee pain during walking. Peak KAM was significantly lower when wearing the rocker-soled shoes compared with that when wearing the non-rocker-soled shoes (mean difference (95% confidence interval), -0.27 (-0.42 to -0.12) N·m/BW × Ht%; P shoe conditions (P = 0.13). Both peak KAM and KAM impulse were significantly higher during both shoe conditions compared with those during the barefoot condition (P shoes significantly reduced peak KAM when compared with non-rocker-soled shoes, without a concomitant change in KFM, and thus may potentially reduce medial knee joint loading. However, KAM parameters in the rocker-soled shoes remained significantly higher than those during barefoot walking. Wearing rocker-soled shoes did not have a significant immediate effect on walking pain. Further research is required to evaluate whether rocker-soled shoes can influence symptoms and progression of knee OA with prolonged wear.

  13. Feature-driven model-based segmentation

    Science.gov (United States)

    Qazi, Arish A.; Kim, John; Jaffray, David A.; Pekar, Vladimir

    2011-03-01

    The accurate delineation of anatomical structures is required in many medical image analysis applications. One example is radiation therapy planning (RTP), where traditional manual delineation is tedious, labor intensive, and can require hours of clinician's valuable time. Majority of automated segmentation methods in RTP belong to either model-based or atlas-based approaches. One substantial limitation of model-based segmentation is that its accuracy may be restricted by the uncertainties in image content, specifically when segmenting low-contrast anatomical structures, e.g. soft tissue organs in computed tomography images. In this paper, we introduce a non-parametric feature enhancement filter which replaces raw intensity image data by a high level probabilistic map which guides the deformable model to reliably segment low-contrast regions. The method is evaluated by segmenting the submandibular and parotid glands in the head and neck region and comparing the results to manual segmentations in terms of the volume overlap. Quantitative results show that we are in overall good agreement with expert segmentations, achieving volume overlap of up to 80%. Qualitatively, we demonstrate that we are able to segment low-contrast regions, which otherwise are difficult to delineate with deformable models relying on distinct object boundaries from the original image data.

  14. Chemicals as the Sole Transformers of Cell Fate.

    Science.gov (United States)

    Ebrahimi, Behnam

    2016-05-30

    Forced expression of lineage-specific transcription factors in somatic cells can result in the generation of different cell types in a process named direct reprogramming, bypassing the pluripotent state. However, the introduction of transgenes limits the therapeutic applications of the produced cells. Numerous small-molecules have been introduced in the field of stem cell biology capable of governing self-renewal, reprogramming, transdifferentiation and regeneration. These chemical compounds are versatile tools for cell fate conversion toward desired outcomes. Cell fate conversion using small-molecules alone (chemical reprogramming) has superiority over arduous traditional genetic techniques in several aspects. For instance, rapid, transient, and reversible effects in activation and inhibition of functions of specific proteins are of the profits of small-molecules. They are cost-effective, have a long half-life, diversity on structure and function, and allow for temporal and flexible regulation of signaling pathways. Additionally, their effects could be adjusted by fine-tuning concentrations and combinations of different small-molecules. Therefore, chemicals are powerful tools in cell fate conversion and study of stem cell and chemical biology in vitro and in vivo. Moreover, transgene-free and chemical-only transdifferentiation approaches provide alternative strategies for the generation of various cell types, disease modeling, drug screening, and regenerative medicine. The current review gives an overview of the recent findings concerning transdifferentiation by only small-molecules without the use of transgenes.

  15. SLS Model Based Design: A Navigation Perspective

    Science.gov (United States)

    Oliver, T. Emerson; Anzalone, Evan; Park, Thomas; Geohagan, Kevin

    2018-01-01

    The SLS Program has implemented a Model-based Design (MBD) and Model-based Requirements approach for managing component design information and system requirements. This approach differs from previous large-scale design efforts at Marshall Space Flight Center where design documentation alone conveyed information required for vehicle design and analysis and where extensive requirements sets were used to scope and constrain the design. The SLS Navigation Team is responsible for the Program-controlled Design Math Models (DMMs) which describe and represent the performance of the Inertial Navigation System (INS) and the Rate Gyro Assemblies (RGAs) used by Guidance, Navigation, and Controls (GN&C). The SLS Navigation Team is also responsible for navigation algorithms. The navigation algorithms are delivered for implementation on the flight hardware as a DMM. For the SLS Block 1B design, the additional GPS Receiver hardware model is managed as a DMM at the vehicle design level. This paper describes the models, and discusses the processes and methods used to engineer, design, and coordinate engineering trades and performance assessments using SLS practices as applied to the GN&C system, with a particular focus on the navigation components.

  16. Divergence-based tests for model diagnostic

    Czech Academy of Sciences Publication Activity Database

    Hobza, Tomáš; Esteban, M. D.; Morales, D.; Marhuenda, Y.

    2008-01-01

    Roč. 78, č. 13 (2008), s. 1702-1710 ISSN 0167-7152 R&D Projects: GA MŠk 1M0572 Grant - others:Instituto Nacional de Estadistica (ES) MTM2006-05693 Institutional research plan: CEZ:AV0Z10750506 Keywords : goodness of fit * devergence statistics * GLM * model checking * bootstrap Subject RIV: BB - Applied Statistics, Operational Research Impact factor: 0.445, year: 2008 http://library.utia.cas.cz/separaty/2008/SI/hobza-divergence-based%20tests%20for%20model%20diagnostic.pdf

  17. Process-Based Modeling of Constructed Wetlands

    Science.gov (United States)

    Baechler, S.; Brovelli, A.; Rossi, L.; Barry, D. A.

    2007-12-01

    Constructed wetlands (CWs) are widespread facilities for wastewater treatment. In subsurface flow wetlands, contaminated wastewater flows through a porous matrix, where oxidation and detoxification phenomena occur. Despite the large number of working CWs, system design and optimization are still mainly based upon empirical equations or simplified first-order kinetics. This results from an incomplete understanding of the system functioning, and may in turn hinder the performance and effectiveness of the treatment process. As a result, CWs are often considered not suitable to meet high water quality-standards, or to treat water contaminated with recalcitrant anthropogenic contaminants. To date, only a limited number of detailed numerical models have been developed and successfully applied to simulate constructed wetland behavior. Among these, one of the most complete and powerful is CW2D, which is based on Hydrus2D. The aim of this work is to develop a comprehensive simulator tailored to model the functioning of horizontal flow constructed wetlands and in turn provide a reliable design and optimization tool. The model is based upon PHWAT, a general reactive transport code for saturated flow. PHWAT couples MODFLOW, MT3DMS and PHREEQC-2 using an operator-splitting approach. The use of PHREEQC to simulate reactions allows great flexibility in simulating biogeochemical processes. The biogeochemical reaction network is similar to that of CW2D, and is based on the Activated Sludge Model (ASM). Kinetic oxidation of carbon sources and nutrient transformations (nitrogen and phosphorous primarily) are modeled via Monod-type kinetic equations. Oxygen dissolution is accounted for via a first-order mass-transfer equation. While the ASM model only includes a limited number of kinetic equations, the new simulator permits incorporation of an unlimited number of both kinetic and equilibrium reactions. Changes in pH, redox potential and surface reactions can be easily incorporated

  18. Model transformation based information system modernization

    Directory of Open Access Journals (Sweden)

    Olegas Vasilecas

    2013-03-01

    Full Text Available Information systems begin to date increasingly faster because of rapidly changing business environment. Usually, small changes are not sufficient to adapt complex legacy information systems to changing business needs. A new functionality should be installed with the requirement of putting business data in the smallest possible risk. Information systems modernization problems are beeing analyzed in this paper and a method for information system modernization is proposed. It involves programming code transformation into abstract syntax tree metamodel (ASTM and model based transformation from ASTM into knowledge discovery model (KDM. The method is validated on example for SQL language.

  19. Soil organic matter as sole indicator of soil degradation.

    Science.gov (United States)

    Obalum, S E; Chibuike, G U; Peth, S; Ouyang, Y

    2017-04-01

    Soil organic matter (SOM) is known to play vital roles in the maintenance and improvement of many soil properties and processes. These roles, which largely influence soil functions, are a pool of specific contributions of different components of SOM. The soil functions, in turn, normally define the level of soil degradation, viewed as quantifiable temporal changes in a soil that impairs its quality. This paper aims at providing a generalized assessment of the current state of knowledge on the usefulness of SOM in monitoring soil degradation, based on its influence on the physical, chemical and biological properties and processes of soils. Emphasis is placed particularly on the effect of SOM on soil structure and availability of plant nutrients. Although these properties are discussed separately, the soil system is of dynamic and interactive nature, and changes in one property will likely affect other soil properties as well. Thus, functions of SOM almost always affect various soil properties and processes and engage in multiple reactions. In view of its role in soil aggregation and erosion control, in availability of plant nutrients and in ameliorating other forms of soil degradation than erosion, SOM has proven to be an important indicator of soil degradation. It has been suggested, however, that rather than the absolute amount, temporal change and potential amount of SOM be considered in its use as indicator of soil degradation, and that SOM may not be an all-purpose indicator. Whilst SOM remains a candidate without substitute as long as a one-parameter indicator of soil degradation is needed, narrowing down to the use of its labile and microbial components could be more appropriate, since early detection is important in the control and management of soil degradation.

  20. Evaluation of mobile ad hoc network reliability using propagation-based link reliability model

    International Nuclear Information System (INIS)

    Padmavathy, N.; Chaturvedi, Sanjay K.

    2013-01-01

    A wireless mobile ad hoc network (MANET) is a collection of solely independent nodes (that can move randomly around the area of deployment) making the topology highly dynamic; nodes communicate with each other by forming a single hop/multi-hop network and maintain connectivity in decentralized manner. MANET is modelled using geometric random graphs rather than random graphs because the link existence in MANET is a function of the geometric distance between the nodes and the transmission range of the nodes. Among many factors that contribute to the MANET reliability, the reliability of these networks also depends on the robustness of the link between the mobile nodes of the network. Recently, the reliability of such networks has been evaluated for imperfect nodes (transceivers) with binary model of communication links based on the transmission range of the mobile nodes and the distance between them. However, in reality, the probability of successful communication decreases as the signal strength deteriorates due to noise, fading or interference effects even up to the nodes' transmission range. Hence, in this paper, using a propagation-based link reliability model rather than a binary-model with nodes following a known failure distribution to evaluate the network reliability (2TR m , ATR m and AoTR m ) of MANET through Monte Carlo Simulation is proposed. The method is illustrated with an application and some imperative results are also presented

  1. Agent-based modeling in ecological economics.

    Science.gov (United States)

    Heckbert, Scott; Baynes, Tim; Reeson, Andrew

    2010-01-01

    Interconnected social and environmental systems are the domain of ecological economics, and models can be used to explore feedbacks and adaptations inherent in these systems. Agent-based modeling (ABM) represents autonomous entities, each with dynamic behavior and heterogeneous characteristics. Agents interact with each other and their environment, resulting in emergent outcomes at the macroscale that can be used to quantitatively analyze complex systems. ABM is contributing to research questions in ecological economics in the areas of natural resource management and land-use change, urban systems modeling, market dynamics, changes in consumer attitudes, innovation, and diffusion of technology and management practices, commons dilemmas and self-governance, and psychological aspects to human decision making and behavior change. Frontiers for ABM research in ecological economics involve advancing the empirical calibration and validation of models through mixed methods, including surveys, interviews, participatory modeling, and, notably, experimental economics to test specific decision-making hypotheses. Linking ABM with other modeling techniques at the level of emergent properties will further advance efforts to understand dynamics of social-environmental systems.

  2. The Drag-based Ensemble Model (DBEM) for Coronal Mass Ejection Propagation

    Science.gov (United States)

    Dumbović, Mateja; Čalogović, Jaša; Vršnak, Bojan; Temmer, Manuela; Mays, M. Leila; Veronig, Astrid; Piantschitsch, Isabell

    2018-02-01

    The drag-based model for heliospheric propagation of coronal mass ejections (CMEs) is a widely used analytical model that can predict CME arrival time and speed at a given heliospheric location. It is based on the assumption that the propagation of CMEs in interplanetary space is solely under the influence of magnetohydrodynamical drag, where CME propagation is determined based on CME initial properties as well as the properties of the ambient solar wind. We present an upgraded version, the drag-based ensemble model (DBEM), that covers ensemble modeling to produce a distribution of possible ICME arrival times and speeds. Multiple runs using uncertainty ranges for the input values can be performed in almost real-time, within a few minutes. This allows us to define the most likely ICME arrival times and speeds, quantify prediction uncertainties, and determine forecast confidence. The performance of the DBEM is evaluated and compared to that of ensemble WSA-ENLIL+Cone model (ENLIL) using the same sample of events. It is found that the mean error is ME = ‑9.7 hr, mean absolute error MAE = 14.3 hr, and root mean square error RMSE = 16.7 hr, which is somewhat higher than, but comparable to ENLIL errors (ME = ‑6.1 hr, MAE = 12.8 hr and RMSE = 14.4 hr). Overall, DBEM and ENLIL show a similar performance. Furthermore, we find that in both models fast CMEs are predicted to arrive earlier than observed, most likely owing to the physical limitations of models, but possibly also related to an overestimation of the CME initial speed for fast CMEs.

  3. Knowledge-based geometric modeling in construction

    DEFF Research Database (Denmark)

    Bonev, Martin; Hvam, Lars

    2012-01-01

    A wider application of IT-based solutions, such as configuration systems and the implementation of modeling standards, has facilitated the trend to produce mass customized products to support inter alia the specification process of the increasing product variety. However, not all industries have...... realized the full potential of using product and process modelling tools as well as the implementation of configuration systems to support their business processes. Especially in the building industry, where Engineer-to-Order (ETO) manufacturers provide complex custom tailored products, up to now, often...... a considerably high amount of their recourses is required for designing and specifying the majority of their product assortment. As design decisions are hereby based on knowledge and experience about behaviour and applicability of construction techniques and materials for a predefined design situation, smart...

  4. Record of high-pressure overprint in metamorphic soles of the Tavşanli zone, Western Anatolia

    Science.gov (United States)

    Plunder, Alexis; Agard, Philippe; Chopin, Christian; Okay, Aral

    2013-04-01

    Large obducted ophiolites correspond to the emplacement of dense oceanic lithosphere on top of a continent and thereby provide insights into rheological and thermal coupling between plates or fluid budgets. Obducted ophiolites thrust onto the continental margin of the Anatolide-Tauride block (Western Anatolia, south of the Izmir-Ankara suture zone) are dated through their metamorphic sole at ca. 90-95Ma and derive from the same intra-oceanic Neotethyan subduction. We herein focus on the metamorphic soles of the Tavşanlı zone, which show a variable high-pressure low-temperature (HP-LT) overprint of the initial amphibolitic metamorphic conditions (Önen & Hall, 1993; Dilek & Whitney, 1997; Okay et al, 1998). Systematic sampling was done in both the already studied areas as well as new locations. PT conditions were estimated at 8 kbar and 700°C for the amphibolitic stage with the assemblage hornblende + plagioclase ± garnet ± epidote. The HP-LT metamorphic overprint reached incipient blueschist to blueschist facies PT conditions. Development of the characteristic assemblage glaucophane + lawsonite yields PT estimates of >6-7 kbar and 300°C. The high-pressure stage is similar to the one observed for the underlying accretionary-complex unit of the Tavşanlı zone (Plunder et al, this meeting). This HP overprint was not observed in other obduction contexts such as Oman or New Caledonia but was documented in Fransciscan Complex amphibolites (Wakayabashi, 1990). The record of two metamorphic events can be understood as: (1) rapid cooling of the subduction zone after initiation and the exhumation of the metamorphic sole; (2) reburial after or during exhumation of the amphibolite initially welded at the base of the ophiolite. Several observations (i.e., lack of tectonic contact between the ophiolitic body and the metamorphic sole, PT estimates,...) point to cooling as the most likely hypothesis. Metamorphic soles allow to highlight: (1) the dynamics of obducted

  5. A Visual Attention Model Based Image Fusion

    OpenAIRE

    Rishabh Gupta; M.R.Vimala Devi; M. Devi

    2013-01-01

    To develop an efficient image fusion algorithm based on visual attention model for images with distinct objects. Image fusion is a process of combining complementary information from multiple images of the same scene into an image, so that the resultant image contains a more accurate description of the scene than any of the individual source images. The two basic fusion techniques are pixel level and region level fusion. Pixel level fusion deals with the operations on each and every pixel sep...

  6. Model based risk assessment - the CORAS framework

    Energy Technology Data Exchange (ETDEWEB)

    Gran, Bjoern Axel; Fredriksen, Rune; Thunem, Atoosa P-J.

    2004-04-15

    Traditional risk analysis and assessment is based on failure-oriented models of the system. In contrast to this, model-based risk assessment (MBRA) utilizes success-oriented models describing all intended system aspects, including functional, operational and organizational aspects of the target. The target models are then used as input sources for complementary risk analysis and assessment techniques, as well as a basis for the documentation of the assessment results. The EU-funded CORAS project developed a tool-supported methodology for the application of MBRA in security-critical systems. The methodology has been tested with successful outcome through a series of seven trial within the telemedicine and ecommerce areas. The CORAS project in general and the CORAS application of MBRA in particular have contributed positively to the visibility of model-based risk assessment and thus to the disclosure of several potentials for further exploitation of various aspects within this important research field. In that connection, the CORAS methodology's possibilities for further improvement towards utilization in more complex architectures and also in other application domains such as the nuclear field can be addressed. The latter calls for adapting the framework to address nuclear standards such as IEC 60880 and IEC 61513. For this development we recommend applying a trial driven approach within the nuclear field. The tool supported approach for combining risk analysis and system development also fits well with the HRP proposal for developing an Integrated Design Environment (IDE) providing efficient methods and tools to support control room systems design. (Author)

  7. Business Models for NFC based mobile payments

    Directory of Open Access Journals (Sweden)

    Johannes Sang Un Chae

    2015-01-01

    Full Text Available Purpose: The purpose of the paper is to develop a business model framework for NFC based mobile payment solutions consisting of four mutually interdepended components: the value service, value network, value architecture, and value finance. Design: Using a comparative case study method, the paper investigates Google Wallet and ISIS Mobile Wallet and their underlying business models. Findings: Google Wallet and ISIS Mobile Wallet are focusing on providing an enhanced customer experience with their mobile wallet through a multifaceted value proposition. The delivery of its offering requires cooperation from multiple stakeholders and the creation of an ecosystem. Furthermore, they focus on the scalability of their value propositions. Originality / value: The paper offers an applicable business model framework that allows practitioners and academics to study current and future mobile payment approaches.

  8. Business Models for NFC Based Mobile Payments

    DEFF Research Database (Denmark)

    Chae, Johannes Sang-Un; Hedman, Jonas

    2015-01-01

    from multiple stakeholders and the creation of an ecosystem. Furthermore, they focus on the scalability of their value propositions. Originality / value: The paper offers an applicable business model framework that allows practitioners and academics to study current and future mobile payment approaches.......Purpose: The purpose of the paper is to develop a business model framework for NFC based mobile payment solutions consisting of four mutually interdepended components: the value service, value network, value architecture, and value finance. Design: Using a comparative case study method, the paper...... investigates Google Wallet and ISIS Mobile Wallet and their underlying business models. Findings: Google Wallet and ISIS Mobile Wallet are focusing on providing an enhanced customer experience with their mobile wallet through a multifaceted value proposition. The delivery of its offering requires cooperation...

  9. AFSC/RACE/GAP/Nichol: Archival tag depth and temperature data from northern rock sole

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Depth data from archival tags on northern rock sole (Lepidopsetta polyxystra) were examined to assess whether fish used tidal currents to aid horizontal migration....

  10. Sequencing Batch Reactor Biodegradation of Hydrolyzed GB as Sole Carbon Source

    National Research Council Canada - National Science Library

    Harvey, Steven

    2002-01-01

    ... % in aqueous sodium hydroxide yielding primarily o-isopropyl methylphosphonic acid (IMPA). This hydrolysate was diluted and fed as sole carbon source to activated sludge in an aerobic sequencing batch reactor...

  11. 31 CFR 353.36 - Payment during life of sole owner.

    Science.gov (United States)

    2010-07-01

    ...) FISCAL SERVICE, DEPARTMENT OF THE TREASURY BUREAU OF THE PUBLIC DEBT REGULATIONS GOVERNING DEFINITIVE... of sole owner. A savings bond registered in single ownership form (i.e., without a coowner or...

  12. 31 CFR 315.36 - Payment during life of sole owner.

    Science.gov (United States)

    2010-07-01

    ...) FISCAL SERVICE, DEPARTMENT OF THE TREASURY BUREAU OF THE PUBLIC DEBT REGULATIONS GOVERNING U.S. SAVINGS... § 315.36 Payment during life of sole owner. A savings bond registered in single ownership form (i.e...

  13. Néron models and base change

    CERN Document Server

    Halle, Lars Halvard

    2016-01-01

    Presenting the first systematic treatment of the behavior of Néron models under ramified base change, this book can be read as an introduction to various subtle invariants and constructions related to Néron models of semi-abelian varieties, motivated by concrete research problems and complemented with explicit examples. Néron models of abelian and semi-abelian varieties have become an indispensable tool in algebraic and arithmetic geometry since Néron introduced them in his seminal 1964 paper. Applications range from the theory of heights in Diophantine geometry to Hodge theory. We focus specifically on Néron component groups, Edixhoven’s filtration and the base change conductor of Chai and Yu, and we study these invariants using various techniques such as models of curves, sheaves on Grothendieck sites and non-archimedean uniformization. We then apply our results to the study of motivic zeta functions of abelian varieties. The final chapter contains a list of challenging open questions. This book is a...

  14. Inference-based procedural modeling of solids

    KAUST Repository

    Biggers, Keith

    2011-11-01

    As virtual environments become larger and more complex, there is an increasing need for more automated construction algorithms to support the development process. We present an approach for modeling solids by combining prior examples with a simple sketch. Our algorithm uses an inference-based approach to incrementally fit patches together in a consistent fashion to define the boundary of an object. This algorithm samples and extracts surface patches from input models, and develops a Petri net structure that describes the relationship between patches along an imposed parameterization. Then, given a new parameterized line or curve, we use the Petri net to logically fit patches together in a manner consistent with the input model. This allows us to easily construct objects of varying sizes and configurations using arbitrary articulation, repetition, and interchanging of parts. The result of our process is a solid model representation of the constructed object that can be integrated into a simulation-based environment. © 2011 Elsevier Ltd. All rights reserved.

  15. Model-Based Analysis of Hand Radiographs

    Science.gov (United States)

    Levitt, Tod S.; Hedgcock, Marcus W.

    1989-05-01

    As a step toward computer assisted imagery interpretation, we are developing algorithms for computed radiography that allow a computer to recognize specific bones and joints, and to identify variations from normal in size, shape and density. In this paper we report on our approach to model-based computer recognition of hands in radiographs. First, image processing hypotheses of the imaged bones. Multiple hypotheses of the size and orientation of the imaged anatomy are matched against stored 3D models fof the relevant bones, obtained from statistically valid populations studies. Probabilities of the hypotheses are accrued using Bayesian inference techniques whose evaluation is guided by the structure of the hand model and the observed image-derived evidence such as anti-parallel edges, local contrast, etc. High probability matches between the hand model and the image data can cue additional image processing-based ssearch for bones, joints and soft-tissue to confirm hypotheses of the location of the imaged hand. At this point multipule disease detection techniques, automated bone age identification, etc. can be employed.

  16. Model-based explanation of plant knowledge

    Energy Technology Data Exchange (ETDEWEB)

    Huuskonen, P.J. [VTT Electronics, Oulu (Finland). Embedded Software

    1997-12-31

    This thesis deals with computer explanation of knowledge related to design and operation of industrial plants. The needs for explanation are motivated through case studies and literature reviews. A general framework for analysing plant explanations is presented. Prototypes demonstrate key mechanisms for implementing parts of the framework. Power plants, steel mills, paper factories, and high energy physics control systems are studied to set requirements for explanation. The main problems are seen to be either lack or abundance of information. Design knowledge in particular is found missing at plants. Support systems and automation should be enhanced with ways to explain plant knowledge to the plant staff. A framework is formulated for analysing explanations of plant knowledge. It consists of three parts: 1. a typology of explanation, organised by the class of knowledge (factual, functional, or strategic) and by the target of explanation (processes, automation, or support systems), 2. an identification of explanation tasks generic for the plant domain, and 3. an identification of essential model types for explanation (structural, behavioural, functional, and teleological). The tasks use the models to create the explanations of the given classes. Key mechanisms are discussed to implement the generic explanation tasks. Knowledge representations based on objects and their relations form a vocabulary to model and present plant knowledge. A particular class of models, means-end models, are used to explain plant knowledge. Explanations are generated through searches in the models. Hypertext is adopted to communicate explanations over dialogue based on context. The results are demonstrated in prototypes. The VICE prototype explains the reasoning of an expert system for diagnosis of rotating machines at power plants. The Justifier prototype explains design knowledge obtained from an object-oriented plant design tool. Enhanced access mechanisms into on-line documentation are

  17. Amyotrophic Lateral Sclerosis Presenting Respiratory Failure as the Sole Initial Manifestation

    Directory of Open Access Journals (Sweden)

    Fuyuki Tateno

    2014-08-01

    Full Text Available It is rare that amyotrophic lateral sclerosis (ALS presents with respiratory failure as the sole initial manifestation. A 72-year-old man with mild chronic obstructive pulmonary disease developed exertional dyspnea for 13 months. He then progressed to limb weakness that led to the diagnosis of ALS. Although rare, ALS can present with respiratory failure as the sole initial manifestation more than 1 year prior to limb weakness.

  18. Do rocker-sole shoes influence postural stability in chronic low back pain? A randomised trial

    Science.gov (United States)

    Morrissey, Matthew; Shortland, Adam; Lewis, Jeremy S

    2016-01-01

    Background People with chronic low back pain (CLBP) demonstrate greater postural instability compared with asymptomatic individuals. Rocker-sole shoes are inherently unstable and may serve as an effective balance training device. This study hypothesised that wearing rocker-sole shoes would result in long-term improvement in barefoot postural stability in people with CLBP. Methods 20 participants with CLBP were randomised to wear rocker-sole or flat-sole shoes for a minimum of 2 hours each day. Participants were assessed barefoot and shod, over three 40 s trials, under 4 posture challenging standing conditions. The primary outcome was postural stability assessed by root mean squared error of centre of pressure (CoP) displacement (CoPRMSE AP) and mean CoP velocity (CoPVELAP), both in the anteroposterior direction, using force plates. Participants' were assessed without knowledge of group allocation at baseline, 6 weeks and 6 months (main outcome point). Analyses were by intention-to-treat. Results At 6 months, data from 11 of 13 (84.6%) of the rocker-sole and 5 of 7 (71.4%) of the flat-sole group were available for analysis. At baseline, there was a mean increase in CoPRMSE AP (6.41 (2.97) mm, pshoes results in greater postural instability than flat-sole shoes, long-term use of rocker-sole shoes did not appear to influence postural stability in people with CLBP. PMID:27900198

  19. Model-Based Method for Sensor Validation

    Science.gov (United States)

    Vatan, Farrokh

    2012-01-01

    Fault detection, diagnosis, and prognosis are essential tasks in the operation of autonomous spacecraft, instruments, and in situ platforms. One of NASA s key mission requirements is robust state estimation. Sensing, using a wide range of sensors and sensor fusion approaches, plays a central role in robust state estimation, and there is a need to diagnose sensor failure as well as component failure. Sensor validation can be considered to be part of the larger effort of improving reliability and safety. The standard methods for solving the sensor validation problem are based on probabilistic analysis of the system, from which the method based on Bayesian networks is most popular. Therefore, these methods can only predict the most probable faulty sensors, which are subject to the initial probabilities defined for the failures. The method developed in this work is based on a model-based approach and provides the faulty sensors (if any), which can be logically inferred from the model of the system and the sensor readings (observations). The method is also more suitable for the systems when it is hard, or even impossible, to find the probability functions of the system. The method starts by a new mathematical description of the problem and develops a very efficient and systematic algorithm for its solution. The method builds on the concepts of analytical redundant relations (ARRs).

  20. ALGORITHMS FOR THE PROGRAMMING OF FOOTWEAR SOLES MOULDS ON WORKING POSTS OF INJECTION MACHINES

    Directory of Open Access Journals (Sweden)

    LUCA Cornelia

    2014-05-01

    Full Text Available The moulds stock necessary for realization in rhythmically conditions, a certain volume of footwear soles depends on some criterions such as: the range of soles for footwear volume daily realized, the sizes structure of those soles for footwear and, respectively, the sizes tally, the technological cycle for an used mould depending on the equipment efficiency, the provide necessity of spare moulds, the using and fixing conditions etc. From the efficiency point of view, the equipments may have two working posts, or more working posts (always, an even number, as 6, 12, 24, 40 posts. Footwear soles manufacturing takes into account the percentage distribution of the size numbers of the size series. When o portative assembly is used for the manufacturing of the footwear soles using the injection with “n” working posts, it is very important an optimum distribution of the working posts. The disadvantages of these equipments are the situations of the no equilibrium programming of the moulds, so that, in one time, some working posts spread out of the work. The paper presents some practical and theoretical solutions for moulds stock programming in portative assembly for footwear soles injection, so that an optimum equilibrium degree of the working posts will obtain

  1. Flow based vs. demand based energy-water modelling

    Science.gov (United States)

    Rozos, Evangelos; Nikolopoulos, Dionysis; Efstratiadis, Andreas; Koukouvinos, Antonios; Makropoulos, Christos

    2015-04-01

    The water flow in hydro-power generation systems is often used downstream to cover other type of demands like irrigation and water supply. However, the typical case is that the energy demand (operation of hydro-power plant) and the water demand do not coincide. Furthermore, the water inflow into a reservoir is a stochastic process. Things become more complicated if renewable resources (wind-turbines or photovoltaic panels) are included into the system. For this reason, the assessment and optimization of the operation of hydro-power systems are challenging tasks that require computer modelling. This modelling should not only simulate the water budget of the reservoirs and the energy production/consumption (pumped-storage), but should also take into account the constraints imposed by the natural or artificial water network using a flow routing algorithm. HYDRONOMEAS, for example, uses an elegant mathematical approach (digraph) to calculate the flow in a water network based on: the demands (input timeseries), the water availability (simulated) and the capacity of the transmission components (properties of channels, rivers, pipes, etc.). The input timeseries of demand should be estimated by another model and linked to the corresponding network nodes. A model that could be used to estimate these timeseries is UWOT. UWOT is a bottom up urban water cycle model that simulates the generation, aggregation and routing of water demand signals. In this study, we explore the potentials of UWOT in simulating the operation of complex hydrosystems that include energy generation. The evident advantage of this approach is the use of a single model instead of one for estimation of demands and another for the system simulation. An application of UWOT in a large scale system is attempted in mainland Greece in an area extending over 130×170 km². The challenges, the peculiarities and the advantages of this approach are examined and critically discussed.

  2. Model based management of a reservoir system

    Energy Technology Data Exchange (ETDEWEB)

    Scharaw, B.; Westerhoff, T. [Fraunhofer IITB, Ilmenau (Germany). Anwendungszentrum Systemtechnik; Puta, H.; Wernstedt, J. [Technische Univ. Ilmenau (Germany)

    2000-07-01

    The main goals of reservoir management systems consist of prevention against flood water damages, the catchment of raw water and keeping all of the quality parameters within their limits besides controlling the water flows. In consideration of these goals a system model of the complete reservoir system Ohra-Schmalwasser-Tambach Dietharz was developed. This model has been used to develop optimized strategies for minimization of raw water production cost, for maximization of electrical energy production and to cover flood situations, as well. Therefore a proper forecast of the inflow to the reservoir from the catchment areas (especially flooding rivers) and the biological processes in the reservoir is important. The forecast model for the inflow to the reservoir is based on the catchment area model of Lorent and Gevers. It uses area precipitation, water supply from the snow cover, evapotranspiration and soil wetness data to calculate the amount of flow in rivers. The other aim of the project is to ensure the raw water quality using quality models, as well. Then a quality driven raw water supply will be possible. (orig.)

  3. Fault diagnosis based on continuous simulation models

    Science.gov (United States)

    Feyock, Stefan

    1987-01-01

    The results are described of an investigation of techniques for using continuous simulation models as basis for reasoning about physical systems, with emphasis on the diagnosis of system faults. It is assumed that a continuous simulation model of the properly operating system is available. Malfunctions are diagnosed by posing the question: how can we make the model behave like that. The adjustments that must be made to the model to produce the observed behavior usually provide definitive clues to the nature of the malfunction. A novel application of Dijkstra's weakest precondition predicate transformer is used to derive the preconditions for producing the required model behavior. To minimize the size of the search space, an envisionment generator based on interval mathematics was developed. In addition to its intended application, the ability to generate qualitative state spaces automatically from quantitative simulations proved to be a fruitful avenue of investigation in its own right. Implementations of the Dijkstra transform and the envisionment generator are reproduced in the Appendix.

  4. Grid based calibration of SWAT hydrological models

    Directory of Open Access Journals (Sweden)

    D. Gorgan

    2012-07-01

    Full Text Available The calibration and execution of large hydrological models, such as SWAT (soil and water assessment tool, developed for large areas, high resolution, and huge input data, need not only quite a long execution time but also high computation resources. SWAT hydrological model supports studies and predictions of the impact of land management practices on water, sediment, and agricultural chemical yields in complex watersheds. The paper presents the gSWAT application as a web practical solution for environmental specialists to calibrate extensive hydrological models and to run scenarios, by hiding the complex control of processes and heterogeneous resources across the grid based high computation infrastructure. The paper highlights the basic functionalities of the gSWAT platform, and the features of the graphical user interface. The presentation is concerned with the development of working sessions, interactive control of calibration, direct and basic editing of parameters, process monitoring, and graphical and interactive visualization of the results. The experiments performed on different SWAT models and the obtained results argue the benefits brought by the grid parallel and distributed environment as a solution for the processing platform. All the instances of SWAT models used in the reported experiments have been developed through the enviroGRIDS project, targeting the Black Sea catchment area.

  5. Physics-based models of the plasmasphere

    Energy Technology Data Exchange (ETDEWEB)

    Jordanova, Vania K [Los Alamos National Laboratory; Pierrard, Vivane [BELGIUM; Goldstein, Jerry [SWRI; Andr' e, Nicolas [ESTEC/ESA; Kotova, Galina A [SRI, RUSSIA; Lemaire, Joseph F [BELGIUM; Liemohn, Mike W [U OF MICHIGAN; Matsui, H [UNIV OF NEW HAMPSHIRE

    2008-01-01

    We describe recent progress in physics-based models of the plasmasphere using the Auid and the kinetic approaches. Global modeling of the dynamics and inAuence of the plasmasphere is presented. Results from global plasmasphere simulations are used to understand and quantify (i) the electric potential pattern and evolution during geomagnetic storms, and (ii) the inAuence of the plasmasphere on the excitation of electromagnetic ion cyclotron (ElvIIC) waves a.nd precipitation of energetic ions in the inner magnetosphere. The interactions of the plasmasphere with the ionosphere a.nd the other regions of the magnetosphere are pointed out. We show the results of simulations for the formation of the plasmapause and discuss the inAuence of plasmaspheric wind and of ultra low frequency (ULF) waves for transport of plasmaspheric material. Theoretical formulations used to model the electric field and plasma distribution in the plasmasphere are given. Model predictions are compared to recent CLUSTER and MAGE observations, but also to results of earlier models and satellite observations.

  6. Does Contemporary Neo-Kantianism Only Allow for Moral Realism or Constructivism? Elements for a Kantian Grounding of Morality Solely on the basis of the Idea of Freedom

    Directory of Open Access Journals (Sweden)

    Martín Fleitas González

    2015-12-01

    Full Text Available The article carries out a reflection on the sources of normativity in contemporary Neo-Kantianism, which has divided Neo-Kantians into realists and constructivists. After analyzing the constructivist Kantianism of Christine Korsgaard, we propose an alternative: that of grounding normativity solely on the idea of freedom, as an internal value or non-normative absolute, as Kant understands it. This proposal makes it possible to outline a Neo-Kantianism that articulates constructivist and realist models on the sole basis of the idea of freedom.

  7. Mathematical modeling of acid-base physiology.

    Science.gov (United States)

    Occhipinti, Rossana; Boron, Walter F

    2015-01-01

    pH is one of the most important parameters in life, influencing virtually every biological process at the cellular, tissue, and whole-body level. Thus, for cells, it is critical to regulate intracellular pH (pHi) and, for multicellular organisms, to regulate extracellular pH (pHo). pHi regulation depends on the opposing actions of plasma-membrane transporters that tend to increase pHi, and others that tend to decrease pHi. In addition, passive fluxes of uncharged species (e.g., CO2, NH3) and charged species (e.g., HCO3(-), [Formula: see text] ) perturb pHi. These movements not only influence one another, but also perturb the equilibria of a multitude of intracellular and extracellular buffers. Thus, even at the level of a single cell, perturbations in acid-base reactions, diffusion, and transport are so complex that it is impossible to understand them without a quantitative model. Here we summarize some mathematical models developed to shed light onto the complex interconnected events triggered by acids-base movements. We then describe a mathematical model of a spherical cells-which to our knowledge is the first one capable of handling a multitude of buffer reactions-that our team has recently developed to simulate changes in pHi and pHo caused by movements of acid-base equivalents across the plasma membrane of a Xenopus oocyte. Finally, we extend our work to a consideration of the effects of simultaneous CO2 and HCO3(-) influx into a cell, and envision how future models might extend to other cell types (e.g., erythrocytes) or tissues (e.g., renal proximal-tubule epithelium) important for whole-body pH homeostasis. Copyright © 2015 Elsevier Ltd. All rights reserved.

  8. Model Selection for Equating Testlet-Based Tests in the NEAT Design: An Empirical Study

    Science.gov (United States)

    He, Wei; Li, Feifei; Wolfe, Edward W.; Mao, Xia

    2012-01-01

    For those tests solely composed of testlets, local item independency assumption tends to be violated. This study, by using empirical data from a large-scale state assessment program, was interested in investigates the effects of using different models on equating results under the non-equivalent group anchor-test (NEAT) design. Specifically, the…

  9. Cooperation among liquefied natural gas suppliers. Is rationalization the sole objective?

    International Nuclear Information System (INIS)

    Massol, Olivier; Tchung-Ming, Stephane

    2010-01-01

    This paper examines the development of cooperative strategies between countries exporting Liquefied Natural Gas (LNG) and members of the Gas Exporting Countries Forum (GECF). This economic study focuses specifically on an often-raised scenario: the emergence of a cooperative approach designed with the sole aim of logistic rationalization, and which would not have any effect on LNG prices. We first assess the annual gains that may result from this market-power-free cooperative approach using a simple static transportation model. The numerical results obtained suggest that, in the absence of a gain redistribution policy, this cooperative strategy will probably not be adopted because cooperation would not be a rational move for some exporters. The problem of gain sharing is then formulated using cooperative game theory concepts. Several gain-sharing methods have been studied, including the Shapley value and various nucleolus-inspired concepts. Our results suggest that the choice of a redistribution policy appears relatively restricted. Out of the methods studied, only one - per capita nucleolus - satisfies two key requirements. core belonging and monotonicity (in the aggregate). Lastly, we look at how cooperation may give rise to a coordination cost and try to determine the maximum amount of this cost. In view of the low level of this amount and the relative complexity of the sharing method implemented, we consider that the credibility of a logistic cooperation scenario exempt from market power should be reappraised. (author)

  10. Photobiological hydrogen production by using olive mill wastewater as a sole substrate source

    Energy Technology Data Exchange (ETDEWEB)

    Eroglu, Ela; Eroglu, Inci [Middle East Technical Univ., Dept. of Chemical Engineering, Ankara (Turkey); Gunduz, Ufuk; Yucel, Meral [Middle East Technical Univ., Dept. of Biology, Ankara (Turkey); Turker, Lemi [Middle East Technical Univ., Dept. of Chemistry, Ankara (Turkey)

    2004-02-01

    In the present work olive mill wastewater (OMW) collected from West Anatolia-Turkey during 2001, containing 36.02 g carbon, 5.26 g hydrogen, and 0.96 g nitrogen in 100 g suspended solid was used as a sole substrate for the production of hydrogen gas by Rhodobacter sphaeroides O.U.001 in 400 ml glass, column-photobioreactors. Hydrogen production studies on diluted-OMW were investigated in the range of 20% (v/v) and 1% (v/v) OMW containing media. Below 5% OMW containing media, bacterial growth rate fitted well to the logistic model where hydrogen production was observed for the ones below 4% OMW. A maximum hydrogen production potential (HPP) of 13.9 l{sub H2} /l{sub OMW} was obtained at 2% OMW. During the biological hydrogen production process, chemical oxygen demand (COD) of the diluted wastewater decreased from 1100 to 720 mg/l; biochemical oxygen demand (BOD) decreased from 475 to 200 mg/l, and the total recoverable phenol content (ortho- and meta-substitutions) decreased from 2.32 to 0.93 mg/l. In addition, valuable by-products such as carotenoid (40 mg/l{sub OMW}) and polyhydroxybutyrate (PHB) (60 mg/l{sub OMW}) were obtained. According to these results, OMW was concluded to be a very promising substrate source for biohydrogen production process, with additional benefits of its utilization with regard to environmental and economical aspects. (Author)

  11. Cooperation among liquefied natural gas suppliers: Is rationalization the sole objective?

    International Nuclear Information System (INIS)

    MASSOL, Olivier; TCHUNG-MING, Stephane

    2009-01-01

    This paper examines the development of cooperative strategies between 12 countries exporting Liquefied Natural Gas (LNG) and belonging to the Gas Exporting Countries Forum (GECF). This economic study is more specifically focused on a scenario often raised: that of the emergence of a cooperative approach designed with the sole aim of logistic rationalization, and which would not have any effect on LNG prices. As this is a standard transportation problem, we first assess the gains that may result from this cooperative approach using a simple static model calibrated on the year 2007. The numerical results obtained suggest that, in the absence of a gain redistribution policy, this cooperative strategy will probably not be adopted because cooperation would not be a rational move for some exporters. The problem of gain sharing is then formulated using cooperative game theory concepts. Several gain sharing methods have been studied, including the Shapley value and various nucleolus-inspired concepts. Our results suggest that the choice of a redistribution policy appears relatively restricted. Out of the methods studied, only one - the per capita nucleolus - satisfies two key requirements: core belonging and mono-tonicity (in the aggregate). Lastly, coordination costs are considered and we determine the maximum amount that can be tolerated by such a cooperation. In view of the low level of this amount and the relative complexity of the sharing method implemented, we consider that the credibility of a logistic cooperation scenario exempt from market power should be reappraised. (authors)

  12. Model-based phase-shifting interferometer

    Science.gov (United States)

    Liu, Dong; Zhang, Lei; Shi, Tu; Yang, Yongying; Chong, Shiyao; Miao, Liang; Huang, Wei; Shen, Yibing; Bai, Jian

    2015-10-01

    A model-based phase-shifting interferometer (MPI) is developed, in which a novel calculation technique is proposed instead of the traditional complicated system structure, to achieve versatile, high precision and quantitative surface tests. In the MPI, the partial null lens (PNL) is employed to implement the non-null test. With some alternative PNLs, similar as the transmission spheres in ZYGO interferometers, the MPI provides a flexible test for general spherical and aspherical surfaces. Based on modern computer modeling technique, a reverse iterative optimizing construction (ROR) method is employed for the retrace error correction of non-null test, as well as figure error reconstruction. A self-compiled ray-tracing program is set up for the accurate system modeling and reverse ray tracing. The surface figure error then can be easily extracted from the wavefront data in forms of Zernike polynomials by the ROR method. Experiments of the spherical and aspherical tests are presented to validate the flexibility and accuracy. The test results are compared with those of Zygo interferometer (null tests), which demonstrates the high accuracy of the MPI. With such accuracy and flexibility, the MPI would possess large potential in modern optical shop testing.

  13. Physiologically Based Pharmacokinetic (PBPK) Modeling of ...

    Science.gov (United States)

    Background: Quantitative estimation of toxicokinetic variability in the human population is a persistent challenge in risk assessment of environmental chemicals. Traditionally, inter-individual differences in the population are accounted for by default assumptions or, in rare cases, are based on human toxicokinetic data.Objectives: To evaluate the utility of genetically diverse mouse strains for estimating toxicokinetic population variability for risk assessment, using trichloroethylene (TCE) metabolism as a case study. Methods: We used data on oxidative and glutathione conjugation metabolism of TCE in 16 inbred and one hybrid mouse strains to calibrate and extend existing physiologically-based pharmacokinetic (PBPK) models. We added one-compartment models for glutathione metabolites and a two-compartment model for dichloroacetic acid (DCA). A Bayesian population analysis of inter-strain variability was used to quantify variability in TCE metabolism. Results: Concentration-time profiles for TCE metabolism to oxidative and glutathione conjugation metabolites varied across strains. Median predictions for the metabolic flux through oxidation was less variable (5-fold range) than that through glutathione conjugation (10-fold range). For oxidative metabolites, median predictions of trichloroacetic acid production was less variable (2-fold range) than DCA production (5-fold range), although uncertainty bounds for DCA exceeded the predicted variability. Conclusions:

  14. Model-Based Fault Tolerant Control

    Science.gov (United States)

    Kumar, Aditya; Viassolo, Daniel

    2008-01-01

    The Model Based Fault Tolerant Control (MBFTC) task was conducted under the NASA Aviation Safety and Security Program. The goal of MBFTC is to develop and demonstrate real-time strategies to diagnose and accommodate anomalous aircraft engine events such as sensor faults, actuator faults, or turbine gas-path component damage that can lead to in-flight shutdowns, aborted take offs, asymmetric thrust/loss of thrust control, or engine surge/stall events. A suite of model-based fault detection algorithms were developed and evaluated. Based on the performance and maturity of the developed algorithms two approaches were selected for further analysis: (i) multiple-hypothesis testing, and (ii) neural networks; both used residuals from an Extended Kalman Filter to detect the occurrence of the selected faults. A simple fusion algorithm was implemented to combine the results from each algorithm to obtain an overall estimate of the identified fault type and magnitude. The identification of the fault type and magnitude enabled the use of an online fault accommodation strategy to correct for the adverse impact of these faults on engine operability thereby enabling continued engine operation in the presence of these faults. The performance of the fault detection and accommodation algorithm was extensively tested in a simulation environment.

  15. Model-based optimization biofilm based systems performing autotrophic nitrogen removal using the comprehensive NDHA model

    DEFF Research Database (Denmark)

    Valverde Pérez, Borja; Ma, Yunjie; Morset, Martin

    Completely autotrophic nitrogen removal (CANR) can be obtained in single stage biofilm-based bioreactors. However, their environmental footprint is compromised due to elevated N2O emissions. We developed novel spatially explicit biochemical process model of biofilm based CANR systems that predicts...

  16. Integration of Simulink Models with Component-based Software Models

    DEFF Research Database (Denmark)

    Marian, Nicolae

    2008-01-01

    , communication and constraints, using computational blocks and aggregates for both discrete and continuous behaviour, different interconnection and execution disciplines for event-based and time-based controllers, and so on, to encompass the demands to more functionality, at even lower prices, and with opposite...... to be analyzed. One way of doing that is to integrate in wrapper files the model back into Simulink S-functions, and use its extensive simulation features, thus allowing an early exploration of the possible design choices over multiple disciplines. The paper describes a safe translation of a restricted set...... of MATLAB/Simulink blocks to COMDES software components, both for continuous and discrete behaviour, and the transformation of the software system into the S-functions. The general aim of this work is the improvement of multi-disciplinary development of embedded systems with the focus on the relation...

  17. Model-based Prognostics with Concurrent Damage Progression Processes

    Data.gov (United States)

    National Aeronautics and Space Administration — Model-based prognostics approaches rely on physics-based models that describe the behavior of systems and their components. These models must account for the several...

  18. Model Based Autonomy for Robust Mars Operations

    Science.gov (United States)

    Kurien, James A.; Nayak, P. Pandurang; Williams, Brian C.; Lau, Sonie (Technical Monitor)

    1998-01-01

    Space missions have historically relied upon a large ground staff, numbering in the hundreds for complex missions, to maintain routine operations. When an anomaly occurs, this small army of engineers attempts to identify and work around the problem. A piloted Mars mission, with its multiyear duration, cost pressures, half-hour communication delays and two-week blackouts cannot be closely controlled by a battalion of engineers on Earth. Flight crew involvement in routine system operations must also be minimized to maximize science return. It also may be unrealistic to require the crew have the expertise in each mission subsystem needed to diagnose a system failure and effect a timely repair, as engineers did for Apollo 13. Enter model-based autonomy, which allows complex systems to autonomously maintain operation despite failures or anomalous conditions, contributing to safe, robust, and minimally supervised operation of spacecraft, life support, In Situ Resource Utilization (ISRU) and power systems. Autonomous reasoning is central to the approach. A reasoning algorithm uses a logical or mathematical model of a system to infer how to operate the system, diagnose failures and generate appropriate behavior to repair or reconfigure the system in response. The 'plug and play' nature of the models enables low cost development of autonomy for multiple platforms. Declarative, reusable models capture relevant aspects of the behavior of simple devices (e.g. valves or thrusters). Reasoning algorithms combine device models to create a model of the system-wide interactions and behavior of a complex, unique artifact such as a spacecraft. Rather than requiring engineers to all possible interactions and failures at design time or perform analysis during the mission, the reasoning engine generates the appropriate response to the current situation, taking into account its system-wide knowledge, the current state, and even sensor failures or unexpected behavior.

  19. Human physiologically based pharmacokinetic model for propofol

    Directory of Open Access Journals (Sweden)

    Schnider Thomas W

    2005-04-01

    Full Text Available Abstract Background Propofol is widely used for both short-term anesthesia and long-term sedation. It has unusual pharmacokinetics because of its high lipid solubility. The standard approach to describing the pharmacokinetics is by a multi-compartmental model. This paper presents the first detailed human physiologically based pharmacokinetic (PBPK model for propofol. Methods PKQuest, a freely distributed software routine http://www.pkquest.com, was used for all the calculations. The "standard human" PBPK parameters developed in previous applications is used. It is assumed that the blood and tissue binding is determined by simple partition into the tissue lipid, which is characterized by two previously determined set of parameters: 1 the value of the propofol oil/water partition coefficient; 2 the lipid fraction in the blood and tissues. The model was fit to the individual experimental data of Schnider et. al., Anesthesiology, 1998; 88:1170 in which an initial bolus dose was followed 60 minutes later by a one hour constant infusion. Results The PBPK model provides a good description of the experimental data over a large range of input dosage, subject age and fat fraction. Only one adjustable parameter (the liver clearance is required to describe the constant infusion phase for each individual subject. In order to fit the bolus injection phase, for 10 or the 24 subjects it was necessary to assume that a fraction of the bolus dose was sequestered and then slowly released from the lungs (characterized by two additional parameters. The average weighted residual error (WRE of the PBPK model fit to the both the bolus and infusion phases was 15%; similar to the WRE for just the constant infusion phase obtained by Schnider et. al. using a 6-parameter NONMEM compartmental model. Conclusion A PBPK model using standard human parameters and a simple description of tissue binding provides a good description of human propofol kinetics. The major advantage of a

  20. Particle-based model for skiing traffic.

    Science.gov (United States)

    Holleczek, Thomas; Tröster, Gerhard

    2012-05-01

    We develop and investigate a particle-based model for ski slope traffic. Skiers are modeled as particles with a mass that are exposed to social and physical forces, which define the riding behavior of skiers during their descents on ski slopes. We also report position and speed data of 21 skiers recorded with GPS-equipped cell phones on two ski slopes. A comparison of these data with the trajectories resulting from computer simulations of our model shows a good correspondence. A study of the relationship among the density, speed, and flow of skiers reveals that congestion does not occur even with arrival rates of skiers exceeding the maximum ski lift capacity. In a sensitivity analysis, we identify the kinetic friction coefficient of skis on snow, the skier mass, the range of repelling social forces, and the arrival rate of skiers as the crucial parameters influencing the simulation results. Our model allows for the prediction of speed zones and skier densities on ski slopes, which is important in the prevention of skiing accidents.

  1. Particle-based model for skiing traffic

    Science.gov (United States)

    Holleczek, Thomas; Tröster, Gerhard

    2012-05-01

    We develop and investigate a particle-based model for ski slope traffic. Skiers are modeled as particles with a mass that are exposed to social and physical forces, which define the riding behavior of skiers during their descents on ski slopes. We also report position and speed data of 21 skiers recorded with GPS-equipped cell phones on two ski slopes. A comparison of these data with the trajectories resulting from computer simulations of our model shows a good correspondence. A study of the relationship among the density, speed, and flow of skiers reveals that congestion does not occur even with arrival rates of skiers exceeding the maximum ski lift capacity. In a sensitivity analysis, we identify the kinetic friction coefficient of skis on snow, the skier mass, the range of repelling social forces, and the arrival rate of skiers as the crucial parameters influencing the simulation results. Our model allows for the prediction of speed zones and skier densities on ski slopes, which is important in the prevention of skiing accidents.

  2. Physiologically based quantitative modeling of unihemispheric sleep.

    Science.gov (United States)

    Kedziora, D J; Abeysuriya, R G; Phillips, A J K; Robinson, P A

    2012-12-07

    Unihemispheric sleep has been observed in numerous species, including birds and aquatic mammals. While knowledge of its functional role has been improved in recent years, the physiological mechanisms that generate this behavior remain poorly understood. Here, unihemispheric sleep is simulated using a physiologically based quantitative model of the mammalian ascending arousal system. The model includes mutual inhibition between wake-promoting monoaminergic nuclei (MA) and sleep-promoting ventrolateral preoptic nuclei (VLPO), driven by circadian and homeostatic drives as well as cholinergic and orexinergic input to MA. The model is extended here to incorporate two distinct hemispheres and their interconnections. It is postulated that inhibitory connections between VLPO nuclei in opposite hemispheres are responsible for unihemispheric sleep, and it is shown that contralateral inhibitory connections promote unihemispheric sleep while ipsilateral inhibitory connections promote bihemispheric sleep. The frequency of alternating unihemispheric sleep bouts is chiefly determined by sleep homeostasis and its corresponding time constant. It is shown that the model reproduces dolphin sleep, and that the sleep regimes of humans, cetaceans, and fur seals, the latter both terrestrially and in a marine environment, require only modest changes in contralateral connection strength and homeostatic time constant. It is further demonstrated that fur seals can potentially switch between their terrestrial bihemispheric and aquatic unihemispheric sleep patterns by varying just the contralateral connection strength. These results provide experimentally testable predictions regarding the differences between species that sleep bihemispherically and unihemispherically. Copyright © 2012 Elsevier Ltd. All rights reserved.

  3. Diminishing musyarakah investment model based on equity

    Science.gov (United States)

    Jaffar, Maheran Mohd; Zain, Shaharir Mohamad; Jemain, Abdul Aziz

    2017-11-01

    Most of the mudharabah and musyarakah contract funds are involved in debt financing. This does not support the theory that profit sharing contract is better than that of debt financing due to the sharing of risks and ownership of equity. Indeed, it is believed that Islamic banking is a financial model based on equity or musyarakah which emphasis on the sharing of risks, profit and loss in the investment between the investor and entrepreneur. The focus of this paper is to introduce the mathematical model that internalizes diminishing musyarakah, the sharing of profit and equity between entrepreneur and investor. The entrepreneur pays monthly-differed payment to buy out the equity that belongs to the investor (bank) where at the end of the specified period, the entrepreneur owns the business and the investor (bank) exits the joint venture. The model is able to calculate the amount of equity at any time for both parties and hence would be a guide in helping to estimate the value of investment should the entrepreneur or investor exit before the end of the specified period. The model is closer to the Islamic principles for justice and fairness.

  4. A Comparison of Filter-based Approaches for Model-based Prognostics

    Data.gov (United States)

    National Aeronautics and Space Administration — Model-based prognostics approaches use domain knowledge about a system and its failure modes through the use of physics-based models. Model-based prognosis is...

  5. Rising incidence of thyroid cancer in Singapore not solely due to micropapillary subtype.

    Science.gov (United States)

    Shulin, J H; Aizhen, J; Kuo, S M; Tan, W B; Ngiam, K Y; Parameswaran, R

    2018-04-01

    Introduction The annual incidence of thyroid cancer is known to vary with geographic area, age and gender. The increasing incidence of thyroid cancer has been attributed to increase in detection of micropapillary subtype, among other factors. The aim of the study was to investigate time trends in the incidence of thyroid cancer in Singapore, an iodine-sufficient area. Materials and methods Data retrieved from the Singapore National Cancer Registry on all thyroid cancers that were diagnosed from 1974 to 2013 were reviewed. We studied the time trends of thyroid cancer based on gender, race, pathology and treatment modalities where available. Results The age-standardised incidence rate of thyroid cancer increased to 5.6/100,000 in 2013 from 2.5/100,000 in 1974. Thyroid cancer appeared to be more common in women, with a higher incidence in Chinese and Malays compared with Indians. Papillary carcinoma is the most common subtype. The percentage of papillary microcarcinoma has remained relatively stable at around 38% of all papillary cancers between 2007 and 2013. Although the incidence of thyroid cancer has increased since 1974, the mortality rate has remained stable. Conclusion This trend of increase in incidence of thyroid cancer in Singapore compares with other published series; however, the rise seen was not solely due to micropapillary type. Thyroid cancer was also more common in Chinese and Malays compared with Indians for reasons that needs to be studied further.

  6. Agent-based models of cellular systems.

    Science.gov (United States)

    Cannata, Nicola; Corradini, Flavio; Merelli, Emanuela; Tesei, Luca

    2013-01-01

    Software agents are particularly suitable for engineering models and simulations of cellular systems. In a very natural and intuitive manner, individual software components are therein delegated to reproduce "in silico" the behavior of individual components of alive systems at a given level of resolution. Individuals' actions and interactions among individuals allow complex collective behavior to emerge. In this chapter we first introduce the readers to software agents and multi-agent systems, reviewing the evolution of agent-based modeling of biomolecular systems in the last decade. We then describe the main tools, platforms, and methodologies available for programming societies of agents, possibly profiting also of toolkits that do not require advanced programming skills.

  7. A physiologically based model for denitrogenation kinetics

    Directory of Open Access Journals (Sweden)

    Ira Katz

    2017-01-01

    Full Text Available Under normal conditions we continuously breathe 78% nitrogen (N2 such that the body tissues and fluids are saturated with dissolved N2. For normobaric medical gas administration at high concentrations, the N2 concentration must be less than that in the ambient atmosphere; therefore, nitrogen will begin to be released by the body tissues. There is a need to estimate the time needed for denitrogenation in the planning of surgical procedures. In this paper we will describe the application of a physiologically based pharmacokinetic model to denitrogenation kinetics. The results are compared to the data resulting from experiments in the literature that measured the end tidal N2 concentration while breathing 100% oxygen in the form of moderately rapid and slow compartment time constants. It is shown that the model is in general agreement with published experimental data. Correlations for denitrogenation as a function of subject weight are provided.

  8. Activity based costing model for inventory valuation

    Directory of Open Access Journals (Sweden)

    Vineet Chouhan

    2017-03-01

    Full Text Available Activity-Based-Model (ABC is used for the purpose of significant improvement for overhead accounting systems by providing the best information required for managerial decision. This pa-per discusses implacability of ABC technique on inventory valuation as a management account-ing innovation. In order to prove the applicability of ABC for inventory control a material driven medium-sized and privately owned company from engineering (iron and steel industry is select-ed and by analysis of its production process and its material dependency and use of indirect in-ventory, an ABC model is explored for better inventory control. The case revealed that the ne-cessity of ABC in the area of inventory control is significant. The company is not only able to increase its quality of decision but also it can significantly analyze its cost of direct material cost, valuation of direct material and use its implications for better decision making.

  9. Average Nuclear properties based on statistical model

    International Nuclear Information System (INIS)

    El-Jaick, L.J.

    1974-01-01

    The rough properties of nuclei were investigated by statistical model, in systems with the same and different number of protons and neutrons, separately, considering the Coulomb energy in the last system. Some average nuclear properties were calculated based on the energy density of nuclear matter, from Weizsscker-Beth mass semiempiric formulae, generalized for compressible nuclei. In the study of a s surface energy coefficient, the great influence exercised by Coulomb energy and nuclear compressibility was verified. For a good adjust of beta stability lines and mass excess, the surface symmetry energy were established. (M.C.K.) [pt

  10. CSPBuilder - CSP based Scientific Workflow Modelling

    DEFF Research Database (Denmark)

    Friborg, Rune Møllegaard; Vinter, Brian

    2008-01-01

    This paper introduces a framework for building CSP based applications, targeted for clusters and next generation CPU designs. CPUs are produced with several cores today and every future CPU generation will feature increasingly more cores, resulting in a requirement for concurrency that has...... not previously been called for. The framework is CSP presented as a scienti¿c work¿ow model, specialized for scienti¿c computing applications. The purpose of the framework is to enable scientists to exploit large parallel computation resources, which has previously been hard due of the dif¿culty of concurrent...

  11. Biologically based multistage modeling of radiation effects

    Energy Technology Data Exchange (ETDEWEB)

    William Hazelton; Suresh Moolgavkar; E. Georg Luebeck

    2005-08-30

    This past year we have made substantial progress in modeling the contribution of homeostatic regulation to low-dose radiation effects and carcinogenesis. We have worked to refine and apply our multistage carcinogenesis models to explicitly incorporate cell cycle states, simple and complex damage, checkpoint delay, slow and fast repair, differentiation, and apoptosis to study the effects of low-dose ionizing radiation in mouse intestinal crypts, as well as in other tissues. We have one paper accepted for publication in ''Advances in Space Research'', and another manuscript in preparation describing this work. I also wrote a chapter describing our combined cell-cycle and multistage carcinogenesis model that will be published in a book on stochastic carcinogenesis models edited by Wei-Yuan Tan. In addition, we organized and held a workshop on ''Biologically Based Modeling of Human Health Effects of Low dose Ionizing Radiation'', July 28-29, 2005 at Fred Hutchinson Cancer Research Center in Seattle, Washington. We had over 20 participants, including Mary Helen Barcellos-Hoff as keynote speaker, talks by most of the low-dose modelers in the DOE low-dose program, experimentalists including Les Redpath (and Mary Helen), Noelle Metting from DOE, and Tony Brooks. It appears that homeostatic regulation may be central to understanding low-dose radiation phenomena. The primary effects of ionizing radiation (IR) are cell killing, delayed cell cycling, and induction of mutations. However, homeostatic regulation causes cells that are killed or damaged by IR to eventually be replaced. Cells with an initiating mutation may have a replacement advantage, leading to clonal expansion of these initiated cells. Thus we have focused particularly on modeling effects that disturb homeostatic regulation as early steps in the carcinogenic process. There are two primary considerations that support our focus on homeostatic regulation. First, a number of

  12. Python-Based Applications for Hydrogeological Modeling

    Science.gov (United States)

    Khambhammettu, P.

    2013-12-01

    Python is a general-purpose, high-level programming language whose design philosophy emphasizes code readability. Add-on packages supporting fast array computation (numpy), plotting (matplotlib), scientific /mathematical Functions (scipy), have resulted in a powerful ecosystem for scientists interested in exploratory data analysis, high-performance computing and data visualization. Three examples are provided to demonstrate the applicability of the Python environment in hydrogeological applications. Python programs were used to model an aquifer test and estimate aquifer parameters at a Superfund site. The aquifer test conducted at a Groundwater Circulation Well was modeled with the Python/FORTRAN-based TTIM Analytic Element Code. The aquifer parameters were estimated with PEST such that a good match was produced between the simulated and observed drawdowns. Python scripts were written to interface with PEST and visualize the results. A convolution-based approach was used to estimate source concentration histories based on observed concentrations at receptor locations. Unit Response Functions (URFs) that relate the receptor concentrations to a unit release at the source were derived with the ATRANS code. The impact of any releases at the source could then be estimated by convolving the source release history with the URFs. Python scripts were written to compute and visualize receptor concentrations for user-specified source histories. The framework provided a simple and elegant way to test various hypotheses about the site. A Python/FORTRAN-based program TYPECURVEGRID-Py was developed to compute and visualize groundwater elevations and drawdown through time in response to a regional uniform hydraulic gradient and the influence of pumping wells using either the Theis solution for a fully-confined aquifer or the Hantush-Jacob solution for a leaky confined aquifer. The program supports an arbitrary number of wells that can operate according to arbitrary schedules. The

  13. Model based control of refrigeration systems

    Energy Technology Data Exchange (ETDEWEB)

    Sloth Larsen, L.F.

    2005-11-15

    The subject for this Ph.D. thesis is model based control of refrigeration systems. Model based control covers a variety of different types of controls, that incorporates mathematical models. In this thesis the main subject therefore has been restricted to deal with system optimizing control. The optimizing control is divided into two layers, where the system oriented top layers deals with set-point optimizing control and the lower layer deals with dynamical optimizing control in the subsystems. The thesis has two main contributions, i.e. a novel approach for set-point optimization and a novel approach for desynchronization based on dynamical optimization. The focus in the development of the proposed set-point optimizing control has been on deriving a simple and general method, that with ease can be applied on various compositions of the same class of systems, such as refrigeration systems. The method is based on a set of parameter depended static equations describing the considered process. By adapting the parameters to the given process, predict the steady state and computing a steady state gradient of the cost function, the process can be driven continuously towards zero gradient, i.e. the optimum (if the cost function is convex). The method furthermore deals with system constrains by introducing barrier functions, hereby the best possible performance taking the given constrains in to account can be obtained, e.g. under extreme operational conditions. The proposed method has been applied on a test refrigeration system, placed at Aalborg University, for minimization of the energy consumption. Here it was proved that by using general static parameter depended system equations it was possible drive the set-points close to the optimum and thus reduce the power consumption with up to 20%. In the dynamical optimizing layer the idea is to optimize the operation of the subsystem or the groupings of subsystems, that limits the obtainable system performance. In systems

  14. 21 CFR 1271.10 - Are my HCT/P's regulated solely under section 361 of the PHS Act and the regulations in this part...

    Science.gov (United States)

    2010-04-01

    ... of the PHS Act and the regulations in this part, and if so what must I do? 1271.10 Section 1271.10...) REGULATIONS UNDER CERTAIN OTHER ACTS ADMINISTERED BY THE FOOD AND DRUG ADMINISTRATION HUMAN CELLS, TISSUES, AND CELLULAR AND TISSUE-BASED PRODUCTS General Provisions § 1271.10 Are my HCT/P's regulated solely...

  15. The estimation of future surface water bodies at Olkiluoto area based on statistical terrain and land uplift models

    International Nuclear Information System (INIS)

    Pohjola, J.; Turunen, J.; Lipping, T.; Ikonen, A.

    2014-03-01

    In this working report the modelling effort of future landscape development and surface water body formation at the modelling area in the vicinity of the Olkiluoto Island is presented. Estimation of the features of future surface water bodies is based on probabilistic terrain and land uplift models presented in previous working reports. The estimation is done using a GIS-based toolbox called UNTAMO. The future surface water bodies are estimated in 10 000 years' time span with 1000 years' intervals for the safety assessment of disposal of spent nuclear fuel at the Olkiluoto site. In the report a brief overview on the techniques used for probabilistic terrain modelling, land uplift modelling and hydrological modelling are presented first. The latter part of the report describes the results of the modelling effort. The main features of the future landscape - the four lakes forming in the vicinity of the Olkiluoto Island - are identified and the probabilistic model of the shoreline displacement is presented. The area and volume of the four lakes is modelled in a probabilistic manner. All the simulations have been performed for three scenarios two of which are based on 10 realizations of the probabilistic digital terrain model (DTM) and 10 realizations of the probabilistic land uplift model. These two scenarios differ from each other by the eustatic curve used in the land uplift model. The third scenario employs 50 realizations of the probabilistic DTM while a deterministic land uplift model, derived solely from the current land uplift rate, is used. The results indicate that the two scenarios based on the probabilistic land uplift model behave in a similar manner while the third model overestimates past and future land uplift rates. The main features of the landscape are nevertheless similar also for the third scenario. Prediction results for the volumes of the future lakes indicate that a couple of highly probably lake formation scenarios can be identified with other

  16. Agent-based modelling in synthetic biology.

    Science.gov (United States)

    Gorochowski, Thomas E

    2016-11-30

    Biological systems exhibit complex behaviours that emerge at many different levels of organization. These span the regulation of gene expression within single cells to the use of quorum sensing to co-ordinate the action of entire bacterial colonies. Synthetic biology aims to make the engineering of biology easier, offering an opportunity to control natural systems and develop new synthetic systems with useful prescribed behaviours. However, in many cases, it is not understood how individual cells should be programmed to ensure the emergence of a required collective behaviour. Agent-based modelling aims to tackle this problem, offering a framework in which to simulate such systems and explore cellular design rules. In this article, I review the use of agent-based models in synthetic biology, outline the available computational tools, and provide details on recently engineered biological systems that are amenable to this approach. I further highlight the challenges facing this methodology and some of the potential future directions. © 2016 The Author(s).

  17. 31 CFR 500.559 - Accounts of North Korean, North Vietnamese, Cambodian or South Vietnamese sole proprietorships.

    Science.gov (United States)

    2010-07-01

    ... Vietnamese, Cambodian or South Vietnamese sole proprietorships. 500.559 Section 500.559 Money and Finance... Licensing Policy § 500.559 Accounts of North Korean, North Vietnamese, Cambodian or South Vietnamese sole proprietorships. Specific licenses are issued unblocking sole proprietorships established under the laws of North...

  18. Intellectual Model-Based Configuration Management Conception

    Directory of Open Access Journals (Sweden)

    Bartusevics Arturs

    2014-07-01

    Full Text Available Software configuration management is one of the most important disciplines within the software development project, which helps control the software evolution process and allows including into the end project only tested and validated changes. To achieve this, software management completes certain tasks. Concrete tools are used for technical implementation of tasks, such as version control systems, servers of continuous integration, compilers, etc. A correct configuration management process usually requires several tools, which mutually exchange information by generating various kinds of transfers. When it comes to introducing the configuration management process, often there are situations when tool installation is started, yet at that given moment there is no general picture of the total process. The article offers a model-based configuration management concept, which foresees the development of an abstract model for the configuration management process that later is transformed to lower abstraction level models and tools are indicated to support the technical process. A solution of this kind allows a more rational introduction and configuration of tools

  19. Use of Physiologically Based Pharmacokinetic (PBPK) Models ...

    Science.gov (United States)

    EPA announced the availability of the final report, Use of Physiologically Based Pharmacokinetic (PBPK) Models to Quantify the Impact of Human Age and Interindividual Differences in Physiology and Biochemistry Pertinent to Risk Final Report for Cooperative Agreement. This report describes and demonstrates techniques necessary to extrapolate and incorporate in vitro derived metabolic rate constants in PBPK models. It also includes two case study examples designed to demonstrate the applicability of such data for health risk assessment and addresses the quantification, extrapolation and interpretation of advanced biochemical information on human interindividual variability of chemical metabolism for risk assessment application. It comprises five chapters; topics and results covered in the first four chapters have been published in the peer reviewed scientific literature. Topics covered include: Data Quality ObjectivesExperimental FrameworkRequired DataTwo example case studies that develop and incorporate in vitro metabolic rate constants in PBPK models designed to quantify human interindividual variability to better direct the choice of uncertainty factors for health risk assessment. This report is intended to serve as a reference document for risk assors to use when quantifying, extrapolating, and interpretating advanced biochemical information about human interindividual variability of chemical metabolism.

  20. Effects of ramp negotiation, paving type and shoe sole geometry on toe clearance in young adults.

    Science.gov (United States)

    Thies, S B; Jones, R K; Kenney, L P J; Howard, D; Baker, R

    2011-10-13

    Trips are a major cause of falls and result from involuntary contact of the foot with the ground during the swing phase of gait. Adequate toe clearance during swing is therefore crucial for safe locomotion. To date, little is known about the effects of environmental factors and footwear on toe clearance. This study reports on modulation of toe clearance and toe clearance variability in response to changes in ground inclination, paving type, and shoe sole geometry. Toe clearance and toe clearance variability for ten healthy young adults were calculated two-fold: a) for the commonly-used position on the foremost part of the sole of the shoe and b) for the lowest of a total of 7 sole positions, located between the metatarsals and the toe tip across the entire width of the sole. Utilizing a full-factorial design we found that toe clearance was affected by ground inclination, paving type, and sole geometry regardless of the computational method used (with p-valuesimportance of considering footwear and environmental factors when assessing the risk of tripping. Future work needs to investigate to which extent the same factors affect toe clearance in more vulnerable parts of the population. Copyright © 2011 Elsevier Ltd. All rights reserved.

  1. Models-Based Practice: Great White Hope or White Elephant?

    Science.gov (United States)

    Casey, Ashley

    2014-01-01

    Background: Many critical curriculum theorists in physical education have advocated a model- or models-based approach to teaching in the subject. This paper explores the literature base around models-based practice (MBP) and asks if this multi-models approach to curriculum planning has the potential to be the great white hope of pedagogical change…

  2. Hazard identification based on plant functional modelling

    International Nuclear Information System (INIS)

    Rasmussen, B.; Whetton, C.

    1993-10-01

    A major objective of the present work is to provide means for representing a process plant as a socio-technical system, so as to allow hazard identification at a high level. The method includes technical, human and organisational aspects and is intended to be used for plant level hazard identification so as to identify critical areas and the need for further analysis using existing methods. The first part of the method is the preparation of a plant functional model where a set of plant functions link together hardware, software, operations, work organisation and other safety related aspects of the plant. The basic principle of the functional modelling is that any aspect of the plant can be represented by an object (in the sense that this term is used in computer science) based upon an Intent (or goal); associated with each Intent are Methods, by which the Intent is realized, and Constraints, which limit the Intent. The Methods and Constraints can themselves be treated as objects and decomposed into lower-level Intents (hence the procedure is known as functional decomposition) so giving rise to a hierarchical, object-oriented structure. The plant level hazard identification is carried out on the plant functional model using the Concept Hazard Analysis method. In this, the user will be supported by checklists and keywords and the analysis is structured by pre-defined worksheets. The preparation of the plant functional model and the performance of the hazard identification can be carried out manually or with computer support. (au) (4 tabs., 10 ills., 7 refs.)

  3. Agent-based models of financial markets

    Science.gov (United States)

    Samanidou, E.; Zschischang, E.; Stauffer, D.; Lux, T.

    2007-03-01

    This review deals with several microscopic ('agent-based') models of financial markets which have been studied by economists and physicists over the last decade: Kim-Markowitz, Levy-Levy-Solomon, Cont-Bouchaud, Solomon-Weisbuch, Lux-Marchesi, Donangelo-Sneppen and Solomon-Levy-Huang. After an overview of simulation approaches in financial economics, we first give a summary of the Donangelo-Sneppen model of monetary exchange and compare it with related models in economics literature. Our selective review then outlines the main ingredients of some influential early models of multi-agent dynamics in financial markets (Kim-Markowitz, Levy-Levy-Solomon). As will be seen, these contributions draw their inspiration from the complex appearance of investors' interactions in real-life markets. Their main aim is to reproduce (and, thereby, provide possible explanations) for the spectacular bubbles and crashes seen in certain historical episodes, but they lack (like almost all the work before 1998 or so) a perspective in terms of the universal statistical features of financial time series. In fact, awareness of a set of such regularities (power-law tails of the distribution of returns, temporal scaling of volatility) only gradually appeared over the nineties. With the more precise description of the formerly relatively vague characteristics (e.g. moving from the notion of fat tails to the more concrete one of a power law with index around three), it became clear that financial market dynamics give rise to some kind of universal scaling law. Showing similarities with scaling laws for other systems with many interacting sub-units, an exploration of financial markets as multi-agent systems appeared to be a natural consequence. This topic has been pursued by quite a number of contributions appearing in both the physics and economics literature since the late nineties. From the wealth of different flavours of multi-agent models that have appeared up to now, we discuss the Cont

  4. Agent-based models of financial markets

    International Nuclear Information System (INIS)

    Samanidou, E; Zschischang, E; Stauffer, D; Lux, T

    2007-01-01

    This review deals with several microscopic ('agent-based') models of financial markets which have been studied by economists and physicists over the last decade: Kim-Markowitz, Levy-Levy-Solomon, Cont-Bouchaud, Solomon-Weisbuch, Lux-Marchesi, Donangelo-Sneppen and Solomon-Levy-Huang. After an overview of simulation approaches in financial economics, we first give a summary of the Donangelo-Sneppen model of monetary exchange and compare it with related models in economics literature. Our selective review then outlines the main ingredients of some influential early models of multi-agent dynamics in financial markets (Kim-Markowitz, Levy-Levy-Solomon). As will be seen, these contributions draw their inspiration from the complex appearance of investors' interactions in real-life markets. Their main aim is to reproduce (and, thereby, provide possible explanations) for the spectacular bubbles and crashes seen in certain historical episodes, but they lack (like almost all the work before 1998 or so) a perspective in terms of the universal statistical features of financial time series. In fact, awareness of a set of such regularities (power-law tails of the distribution of returns, temporal scaling of volatility) only gradually appeared over the nineties. With the more precise description of the formerly relatively vague characteristics (e.g. moving from the notion of fat tails to the more concrete one of a power law with index around three), it became clear that financial market dynamics give rise to some kind of universal scaling law. Showing similarities with scaling laws for other systems with many interacting sub-units, an exploration of financial markets as multi-agent systems appeared to be a natural consequence. This topic has been pursued by quite a number of contributions appearing in both the physics and economics literature since the late nineties. From the wealth of different flavours of multi-agent models that have appeared up to now, we discuss the Cont

  5. The Challenge of Forecasting Metropolitan Growth: Urban Characteristics Based Models versus Regional Dummy Based Models

    OpenAIRE

    NA

    2005-01-01

    This paper presents a study of errors in forecasting the population of Metropolitan Statistical Areas and the Primary MSAs of Consolidated Metropolitan Statistical Areas and New England MAs. The forecasts are for the year 2000 and are based on a semi-structural model estimated by Mills and Lubelle using 1970 to 1990 census data on population, employment and relative real wages. This model allows the testing of regional effects on population and employment growth. The year 2000 forecasts are f...

  6. The Use of Modeling-Based Text to Improve Students' Modeling Competencies

    Science.gov (United States)

    Jong, Jing-Ping; Chiu, Mei-Hung; Chung, Shiao-Lan

    2015-01-01

    This study investigated the effects of a modeling-based text on 10th graders' modeling competencies. Fifteen 10th graders read a researcher-developed modeling-based science text on the ideal gas law that included explicit descriptions and representations of modeling processes (i.e., model selection, model construction, model validation, model…

  7. Model-Based Learning: A Synthesis of Theory and Research

    Science.gov (United States)

    Seel, Norbert M.

    2017-01-01

    This article provides a review of theoretical approaches to model-based learning and related research. In accordance with the definition of model-based learning as an acquisition and utilization of mental models by learners, the first section centers on mental model theory. In accordance with epistemology of modeling the issues of semantics,…

  8. An Ontology-Based Temporal Scheduling and Complexity Reduction Model for Timetabling Knowledge Management

    Directory of Open Access Journals (Sweden)

    Patience Usoro Usip

    2017-08-01

    Full Text Available Technological tools such as Semantic Web and ontologies have contributed immensely to the reduction of most managerial complexities on daily basis. However, most resolved complexities are solely dependent on the emerging issues which are not general enough to accommodate some specific domain challenges. Temporal scheduling complexities occur in several domains including timetabling, but inter-departmental courses allocation on a general institutional timetable has not been considered. This poses serious managerial concerns and threats to the academic performance of any institution. This paper is aimed at formalizing an ontology model for analyzing temporal scheduling complexities in an existing schedule and giving optimal possible time scheduling resolutions showing their reduction rates for efficient and intelligent knowledge management. Protégé was used in modeling the domain ontology described in the resulted ontograf. The semantics of the formal ontology model is described based on Allen’s interval temporal relations. The use of ontologies make way for easy and intelligent reasoning with knowledge and exposes the need for such knowledge management tool to manage the influx of the numerous data.

  9. A physiologically based biodynamic (PBBD) model for estragole DNA binding in rat liver based on in vitro kinetic data and estragole DNA adduct formation in primary hepatocytes

    International Nuclear Information System (INIS)

    Paini, Alicia; Punt, Ans; Viton, Florian; Scholz, Gabriele; Delatour, Thierry; Marin-Kuan, Maricel; Schilter, Benoit; Bladeren, Peter J. van; Rietjens, Ivonne M.C.M.

    2010-01-01

    Estragole has been shown to be hepatocarcinogenic in rodent species at high-dose levels. Translation of these results into the likelihood of formation of DNA adducts, mutation, and ultimately cancer upon more realistic low-dose exposures remains a challenge. Recently we have developed physiologically based biokinetic (PBBK) models for rat and human predicting bioactivation of estragole. These PBBK models, however, predict only kinetic characteristics. The present study describes the extension of the PBBK model to a so-called physiologically based biodynamic (PBBD) model predicting in vivo DNA adduct formation of estragole in rat liver. This PBBD model was developed using in vitro data on DNA adduct formation in rat primary hepatocytes exposed to 1'-hydroxyestragole. The model was extended by linking the area under the curve for 1'-hydroxyestragole formation predicted by the PBBK model to the area under the curve for 1'-hydroxyestragole in the in vitro experiments. The outcome of the PBBD model revealed a linear increase in DNA adduct formation with increasing estragole doses up to 100 mg/kg bw. Although DNA adduct formation of genotoxic carcinogens is generally seen as a biomarker of exposure rather than a biomarker of response, the PBBD model now developed is one step closer to the ultimate toxic effect of estragole than the PBBK model described previously. Comparison of the PBBD model outcome to available data showed that the model adequately predicts the dose-dependent level of DNA adduct formation. The PBBD model predicts DNA adduct formation at low levels of exposure up to a dose level showing to cause cancer in rodent bioassays, providing a proof of principle for modeling a toxicodynamic in vivo endpoint on the basis of solely in vitro experimental data.

  10. A measurement-based generalized source model for Monte Carlo dose simulations of CT scans.

    Science.gov (United States)

    Ming, Xin; Feng, Yuanming; Liu, Ransheng; Yang, Chengwen; Zhou, Li; Zhai, Hezheng; Deng, Jun

    2017-03-07

    The goal of this study is to develop a generalized source model for accurate Monte Carlo dose simulations of CT scans based solely on the measurement data without a priori knowledge of scanner specifications. The proposed generalized source model consists of an extended circular source located at x-ray target level with its energy spectrum, source distribution and fluence distribution derived from a set of measurement data conveniently available in the clinic. Specifically, the central axis percent depth dose (PDD) curves measured in water and the cone output factors measured in air were used to derive the energy spectrum and the source distribution respectively with a Levenberg-Marquardt algorithm. The in-air film measurement of fan-beam dose profiles at fixed gantry was back-projected to generate the fluence distribution of the source model. A benchmarked Monte Carlo user code was used to simulate the dose distributions in water with the developed source model as beam input. The feasibility and accuracy of the proposed source model was tested on a GE LightSpeed and a Philips Brilliance Big Bore multi-detector CT (MDCT) scanners available in our clinic. In general, the Monte Carlo simulations of the PDDs in water and dose profiles along lateral and longitudinal directions agreed with the measurements within 4%/1 mm for both CT scanners. The absolute dose comparison using two CTDI phantoms (16 cm and 32 cm in diameters) indicated a better than 5% agreement between the Monte Carlo-simulated and the ion chamber-measured doses at a variety of locations for the two scanners. Overall, this study demonstrated that a generalized source model can be constructed based only on a set of measurement data and used for accurate Monte Carlo dose simulations of patients' CT scans, which would facilitate patient-specific CT organ dose estimation and cancer risk management in the diagnostic and therapeutic radiology.

  11. Prototype-based models in machine learning.

    Science.gov (United States)

    Biehl, Michael; Hammer, Barbara; Villmann, Thomas

    2016-01-01

    An overview is given of prototype-based models in machine learning. In this framework, observations, i.e., data, are stored in terms of typical representatives. Together with a suitable measure of similarity, the systems can be employed in the context of unsupervised and supervised analysis of potentially high-dimensional, complex datasets. We discuss basic schemes of competitive vector quantization as well as the so-called neural gas approach and Kohonen's topology-preserving self-organizing map. Supervised learning in prototype systems is exemplified in terms of learning vector quantization. Most frequently, the familiar Euclidean distance serves as a dissimilarity measure. We present extensions of the framework to nonstandard measures and give an introduction to the use of adaptive distances in relevance learning. © 2016 Wiley Periodicals, Inc.

  12. Wind Turbine Control: Robust Model Based Approach

    DEFF Research Database (Denmark)

    Mirzaei, Mahmood

    . This is because, on the one hand, control methods can decrease the cost of energy by keeping the turbine close to its maximum efficiency. On the other hand, they can reduce structural fatigue and therefore increase the lifetime of the wind turbine. The power produced by a wind turbine is proportional...... to the square of its rotor radius, therefore it seems reasonable to increase the size of the wind turbine in order to capture more power. However as the size increases, the mass of the blades increases by cube of the rotor size. This means in order to keep structural feasibility and mass of the whole structure...... reasonable, the ratio of mass to size should be reduced. This trend results in more flexible structures. Control of the flexible structure of a wind turbine in a wind field with stochastic nature is very challenging. In this thesis we are examining a number of robust model based methods for wind turbine...

  13. Model based design of electronic throttle control

    Science.gov (United States)

    Cherian, Fenin; Ranjan, Ashish; Bhowmick, Pathikrit; Rammohan, A.

    2017-11-01

    With the advent of torque based Engine Management Systems, the precise control and robust performance of the throttle body becomes a key factor in the overall performance of the vehicle. Electronic Throttle Control provides benefits such as improved air-fuel ratio for improving the vehicle performance and lower exhausts emissions to meet the stringent emission norms. Modern vehicles facilitate various features such as Cruise Control, Traction Control, Electronic Stability Program and Pre-crash systems. These systems require control over engine power without driver intervention, which is not possible with conventional mechanical throttle system. Thus these systems are integrated to function with the electronic throttle control. However, due to inherent non-linearities in the throttle body, the control becomes a difficult task. In order to eliminate the influence of this hysteresis at the initial operation of the butterfly valve, a control to compensate the shortage must be added to the duty required for starting throttle operation when the initial operation is detected. Therefore, a lot of work is being done in this field to incorporate the various nonlinearities to achieve robust control. In our present work, the ETB was tested to verify the working of the system. Calibration of the TPS sensors was carried out in order to acquire accurate throttle opening angle. The response of the calibrated system was then plotted against a step input signal. A linear model of the ETB was prepared using Simulink and its response was compared with the experimental data to find out the initial deviation of the model from the actual system. To reduce this deviation, non-linearities from existing literature were introduced to the system and a response analysis was performed to check the deviation from the actual system. Based on this investigation, an introduction of a new nonlinearity parameter can be used in future to reduce the deviation further making the control of the ETB more

  14. Model Based Vision for Aircraft Position Determination

    Science.gov (United States)

    Sridhar, Banavar; Chatterji, Gano B.; Soni, Tarun; Showman, Robert D. (Technical Monitor)

    1994-01-01

    This paper investigates the use of imaging sensors to estimate the position of an aircraft with respect to the runway during landing. Passive vision techniques to estimate aircraft position during landing rely on the known runway model, images acquired by onboard imaging sensor, orientation information provided by the inertial navigation system and the position estimate provided by devices such as the global positioning system. Point features in the runway model are compared with the onboard sensor images of the features and the difference between the two is used to correct the aircraft position and orientation. In this paper the sensitivity of point features is examined as a means of determining the accuracy of such position estimation techniques. Expressions are derived for the sensitivity of image point to errors in the position and orientation of the sensor. Using these, the sensitivity of the image to aircraft position and orientation errors along a typical landing glide path is studied. A least squares technique based on this sensitivity analysis is described for the correction of position and orientation estimates. The final version of the paper will include results from the application of this analysis to real image sequences collected in flight.

  15. Model-Based Optimizing Control and Estimation Using Modelica Model

    Directory of Open Access Journals (Sweden)

    L. Imsland

    2010-07-01

    Full Text Available This paper reports on experiences from case studies in using Modelica/Dymola models interfaced to control and optimization software, as process models in real time process control applications. Possible applications of the integrated models are in state- and parameter estimation and nonlinear model predictive control. It was found that this approach is clearly possible, providing many advantages over modeling in low-level programming languages. However, some effort is required in making the Modelica models accessible to NMPC software.

  16. Modeling stochastic frontier based on vine copulas

    Science.gov (United States)

    Constantino, Michel; Candido, Osvaldo; Tabak, Benjamin M.; da Costa, Reginaldo Brito

    2017-11-01

    This article models a production function and analyzes the technical efficiency of listed companies in the United States, Germany and England between 2005 and 2012 based on the vine copula approach. Traditional estimates of the stochastic frontier assume that data is multivariate normally distributed and there is no source of asymmetry. The proposed method based on vine copulas allow us to explore different types of asymmetry and multivariate distribution. Using data on product, capital and labor, we measure the relative efficiency of the vine production function and estimate the coefficient used in the stochastic frontier literature for comparison purposes. This production vine copula predicts the value added by firms with given capital and labor in a probabilistic way. It thereby stands in sharp contrast to the production function, where the output of firms is completely deterministic. The results show that, on average, S&P500 companies are more efficient than companies listed in England and Germany, which presented similar average efficiency coefficients. For comparative purposes, the traditional stochastic frontier was estimated and the results showed discrepancies between the coefficients obtained by the application of the two methods, traditional and frontier-vine, opening new paths of non-linear research.

  17. Validating agent based models through virtual worlds.

    Energy Technology Data Exchange (ETDEWEB)

    Lakkaraju, Kiran; Whetzel, Jonathan H.; Lee, Jina; Bier, Asmeret Brooke; Cardona-Rivera, Rogelio E.; Bernstein, Jeremy Ray Rhythm

    2014-01-01

    As the US continues its vigilance against distributed, embedded threats, understanding the political and social structure of these groups becomes paramount for predicting and dis- rupting their attacks. Agent-based models (ABMs) serve as a powerful tool to study these groups. While the popularity of social network tools (e.g., Facebook, Twitter) has provided extensive communication data, there is a lack of ne-grained behavioral data with which to inform and validate existing ABMs. Virtual worlds, in particular massively multiplayer online games (MMOG), where large numbers of people interact within a complex environ- ment for long periods of time provide an alternative source of data. These environments provide a rich social environment where players engage in a variety of activities observed between real-world groups: collaborating and/or competing with other groups, conducting battles for scarce resources, and trading in a market economy. Strategies employed by player groups surprisingly re ect those seen in present-day con icts, where players use diplomacy or espionage as their means for accomplishing their goals. In this project, we propose to address the need for ne-grained behavioral data by acquiring and analyzing game data a commercial MMOG, referred to within this report as Game X. The goals of this research were: (1) devising toolsets for analyzing virtual world data to better inform the rules that govern a social ABM and (2) exploring how virtual worlds could serve as a source of data to validate ABMs established for analogous real-world phenomena. During this research, we studied certain patterns of group behavior to compliment social modeling e orts where a signi cant lack of detailed examples of observed phenomena exists. This report outlines our work examining group behaviors that underly what we have termed the Expression-To-Action (E2A) problem: determining the changes in social contact that lead individuals/groups to engage in a particular behavior

  18. A Collective Case Study of Secondary Students' Model-Based Inquiry on Natural Selection through Programming in an Agent-Based Modeling Environment

    Science.gov (United States)

    Xiang, Lin

    incomplete and many relationships among the model ideas had not been well established by the end of the study. Most of them did not treat the natural selection model as a whole but only focused on some ideas within the model. Very few of them could scientifically apply the natural selection model to interpret other evolutionary phenomena. The findings about participating students' programming processes revealed these processes were composed of consecutive programming cycles. The cycle typically included posing a task, constructing and running program codes, and examining the resulting simulation. Students held multiple ideas and applied various programming strategies in these cycles. Students were involved in MBI at each step of a cycle. Three types of ideas, six programming strategies and ten MBI actions were identified out of the processes. The relationships among these ideas, strategies and actions were also identified and described. Findings suggested that ABPM activities could support MBI by (1) exposing students' personal models and understandings, (2) provoking and supporting a series of model-based inquiry activities, such as elaborating target phenomena, abstracting patterns, and revising conceptual models, and (3) provoking and supporting tangible and productive conversations among students, as well as between the instructor and students. Findings also revealed three programming behaviors that appeared to impede productive MBI, including (1) solely phenomenon-orientated programming, (2) transplanting program codes, and (3) blindly running procedures. Based on the findings, I propose a general modeling process in ABPM activities, summarize the ways in which MBI can be supported in ABPM activities and constrained by multiple factors, and suggest the implications of this study in the future ABPM-assisted science instructional design and research.

  19. SIMULATION MODELING OF IT PROJECTS BASED ON PETRI NETS

    Directory of Open Access Journals (Sweden)

    Александр Михайлович ВОЗНЫЙ

    2015-05-01

    Full Text Available An integrated simulation model of IT project based on a modified Petri net model that combines product and model of project tasks has been proposed. Substantive interpretation of the components of the simulation model has been presented, the process of simulation has been described. The conclusions about the integration of the product model and the model of works project were made.

  20. Intercropping enhances productivity and maintains the most soil fertility properties relative to sole cropping.

    Science.gov (United States)

    Wang, Zhi-Gang; Jin, Xin; Bao, Xing-Guo; Li, Xiao-Fei; Zhao, Jian-Hua; Sun, Jian-Hao; Christie, Peter; Li, Long

    2014-01-01

    Yield and nutrient acquisition advantages are frequently found in intercropping systems. However, there are few published reports on soil fertility in intercropping relative to monocultures. A field experiment was therefore established in 2009 in Gansu province, northwest China. The treatments comprised maize/faba bean, maize/soybean, maize/chickpea and maize/turnip intercropping, and their correspoding monocropping. In 2011 (the 3rd year) and 2012 (the 4th year) the yields and some soil chemical properties and enzyme activities were examined after all crop species were harvested or at later growth stages. Both grain yields and nutrient acquisition were significantly greater in all four intercropping systems than corresponding monocropping over two years. Generally, soil organic matter (OM) did not differ significantly from monocropping but did increase in maize/chickpea in 2012 and maize/turnip in both years. Soil total N (TN) did not differ between intercropping and monocropping in either year with the sole exception of maize/faba bean intercropping receiving 80 kg P ha-1 in 2011. Intercropping significantly reduced soil Olsen-P only in 2012, soil exchangeable K in both years, soil cation exchangeable capacity (CEC) in 2012, and soil pH in 2012. In the majority of cases soil enzyme activities did not differ across all the cropping systems at different P application rates compared to monocrops, with the exception of soil acid phosphatase activity which was higher in maize/legume intercropping than in the corresponding monocrops at 40 kg ha-1 P in 2011. P fertilization can alleviate the decline in soil Olsen-P and in soil CEC to some extent. In summary, intercropping enhanced productivity and maintained the majority of soil fertility properties for at least three to four years, especially at suitable P application rates. The results indicate that maize-based intercropping may be an efficient cropping system for sustainable agriculture with carefully managed

  1. Intercropping Enhances Productivity and Maintains the Most Soil Fertility Properties Relative to Sole Cropping

    Science.gov (United States)

    Wang, Zhi-Gang; Jin, Xin; Bao, Xing-Guo; Li, Xiao-Fei; Zhao, Jian-Hua; Sun, Jian-Hao; Christie, Peter; Li, Long

    2014-01-01

    Yield and nutrient acquisition advantages are frequently found in intercropping systems. However, there are few published reports on soil fertility in intercropping relative to monocultures. A field experiment was therefore established in 2009 in Gansu province, northwest China. The treatments comprised maize/faba bean, maize/soybean, maize/chickpea and maize/turnip intercropping, and their correspoding monocropping. In 2011 (the 3rd year) and 2012 (the 4th year) the yields and some soil chemical properties and enzyme activities were examined after all crop species were harvested or at later growth stages. Both grain yields and nutrient acquisition were significantly greater in all four intercropping systems than corresponding monocropping over two years. Generally, soil organic matter (OM) did not differ significantly from monocropping but did increase in maize/chickpea in 2012 and maize/turnip in both years. Soil total N (TN) did not differ between intercropping and monocropping in either year with the sole exception of maize/faba bean intercropping receiving 80 kg P ha−1 in 2011. Intercropping significantly reduced soil Olsen-P only in 2012, soil exchangeable K in both years, soil cation exchangeable capacity (CEC) in 2012, and soil pH in 2012. In the majority of cases soil enzyme activities did not differ across all the cropping systems at different P application rates compared to monocrops, with the exception of soil acid phosphatase activity which was higher in maize/legume intercropping than in the corresponding monocrops at 40 kg ha−1 P in 2011. P fertilization can alleviate the decline in soil Olsen-P and in soil CEC to some extent. In summary, intercropping enhanced productivity and maintained the majority of soil fertility properties for at least three to four years, especially at suitable P application rates. The results indicate that maize-based intercropping may be an efficient cropping system for sustainable agriculture with carefully managed

  2. A DNA-based semantic fusion model for remote sensing data.

    Science.gov (United States)

    Sun, Heng; Weng, Jian; Yu, Guangchuang; Massawe, Richard H

    2013-01-01

    Semantic technology plays a key role in various domains, from conversation understanding to algorithm analysis. As the most efficient semantic tool, ontology can represent, process and manage the widespread knowledge. Nowadays, many researchers use ontology to collect and organize data's semantic information in order to maximize research productivity. In this paper, we firstly describe our work on the development of a remote sensing data ontology, with a primary focus on semantic fusion-driven research for big data. Our ontology is made up of 1,264 concepts and 2,030 semantic relationships. However, the growth of big data is straining the capacities of current semantic fusion and reasoning practices. Considering the massive parallelism of DNA strands, we propose a novel DNA-based semantic fusion model. In this model, a parallel strategy is developed to encode the semantic information in DNA for a large volume of remote sensing data. The semantic information is read in a parallel and bit-wise manner and an individual bit is converted to a base. By doing so, a considerable amount of conversion time can be saved, i.e., the cluster-based multi-processes program can reduce the conversion time from 81,536 seconds to 4,937 seconds for 4.34 GB source data files. Moreover, the size of result file recording DNA sequences is 54.51 GB for parallel C program compared with 57.89 GB for sequential Perl. This shows that our parallel method can also reduce the DNA synthesis cost. In addition, data types are encoded in our model, which is a basis for building type system in our future DNA computer. Finally, we describe theoretically an algorithm for DNA-based semantic fusion. This algorithm enables the process of integration of the knowledge from disparate remote sensing data sources into a consistent, accurate, and complete representation. This process depends solely on ligation reaction and screening operations instead of the ontology.

  3. An Agent-Based Monetary Production Simulation Model

    DEFF Research Database (Denmark)

    Bruun, Charlotte

    2006-01-01

    An Agent-Based Simulation Model Programmed in Objective Borland Pascal. Program and source code is downloadable......An Agent-Based Simulation Model Programmed in Objective Borland Pascal. Program and source code is downloadable...

  4. Distributed Damage Estimation for Prognostics based on Structural Model Decomposition

    Data.gov (United States)

    National Aeronautics and Space Administration — Model-based prognostics approaches capture system knowl- edge in the form of physics-based models of components that include how they fail. These methods consist of...

  5. Multiple Damage Progression Paths in Model-based Prognostics

    Data.gov (United States)

    National Aeronautics and Space Administration — Model-based prognostics approaches employ do- main knowledge about a system, its components, and how they fail through the use of physics-based models. Compo- nent...

  6. Dynamic Metabolic Model Building Based on the Ensemble Modeling Approach

    Energy Technology Data Exchange (ETDEWEB)

    Liao, James C. [Univ. of California, Los Angeles, CA (United States)

    2016-10-01

    Ensemble modeling of kinetic systems addresses the challenges of kinetic model construction, with respect to parameter value selection, and still allows for the rich insights possible from kinetic models. This project aimed to show that constructing, implementing, and analyzing such models is a useful tool for the metabolic engineering toolkit, and that they can result in actionable insights from models. Key concepts are developed and deliverable publications and results are presented.

  7. Modeling base excision repair in Escherichia coli bacterial cells

    International Nuclear Information System (INIS)

    Belov, O.V.

    2011-01-01

    A model describing the key processes in Escherichia coli bacterial cells during base excision repair is developed. The mechanism is modeled of damaged base elimination involving formamidopyrimidine DNA glycosylase (the Fpg protein), which possesses several types of activities. The modeling of the transitions between DNA states is based on a stochastic approach to the chemical reaction description

  8. Plantar Sole Unweighting Alters the Sensory Transmission to the Cortical Areas

    Directory of Open Access Journals (Sweden)

    Laurence Mouchnino

    2017-05-01

    Full Text Available It is well established that somatosensory inputs to the cortex undergo an early and a later stage of processing. The later has been shown to be enhanced when the earlier transmission decreased. In this framework, mechanical factors such as the mechanical stress to which sensors are subjected when wearing a loaded vest are associated with a decrease in sensory transmission. This decrease is in turn associated with an increase in the late sensory processes originating from cortical areas. We hypothesized that unweighting the plantar sole should lead to a facilitation of the sensory transmission. To test this hypothesis, we recorded cortical somatosensory evoked potentials (SEPs of individuals following cutaneous stimulation (by mean of an electrical stimulation of the foot sole in different conditions of unweighting when standing still with eyes closed. To this end, the effective bodyweight (BW was reduced from 100% BW to 40% BW. Contrary to what was expected, we found an attenuation of sensory information when the BW was unweighted to 41% which was not compensated by an increase of the late SEP component. Overall these results suggested that the attenuation of sensory transmission observed in 40 BW condition was not solely due to the absence of forces acting on the sole of the feet but rather to the current relevance of the afferent signals related to the balance constraints of the task.

  9. Diurnal periodicity in the activity of the common sole, solea vulgaris quensel

    NARCIS (Netherlands)

    Kruuk, H.

    1963-01-01

    1. 1. The diurnal rhythm in the trawl catch of Solea vulgaris Quensel gave rise to this investigation into the diurnal activity rhythm of the fish. 2. 2. Periodicity in the food intake of the Sole in its natural habitat was studied by analyses of the contents of the intestines. Food intake

  10. Navigating Interdependence: How Adolescents Raised Solely by Grandparents Experience Their Family Relationships

    Science.gov (United States)

    Dolbin-MacNab, Megan L.; Keiley, Margaret K.

    2009-01-01

    This study examined how adolescents raised solely by grandparents navigated their relationships with their parents and grandparents and how these relationships were influenced by the caregiving context. Forty-one adolescents participated in qualitative, semistructured interviews. Findings suggest that relationships with parents were primarily…

  11. Variation in the location of the shoe sole flexion point influences plantar loading patterns during gait

    NARCIS (Netherlands)

    van der Zwaard, B.C.; Vanwanseele, B.; Holtkamp, F.; van der Horst, H.E.; Elders, P.J.M.; Menz, H.B.

    2014-01-01

    Background: Several footwear design characteristics are known to have detrimental effects on the foot. However, one characteristic that has received relatively little attention is the point where the sole flexes in the sagittal plane. Several footwear assessment forms assume that this should ideally

  12. The comparison of nitrogen use and leaching in sole cropped versus intercropped pea and barley

    DEFF Research Database (Denmark)

    Hauggaard-Nielsen, H.; Ambus, P.; Jensen, E.S.

    2003-01-01

    was pea and barley sole and intercrops followed by winter-rye and a fallow period. The Land Equivalent Ratio (LER), which is defined as the relative land area under sole crops that is required to produce the yields achieved in intercropping, was used to compare intercropping performance relative to sole...... cropping. Crops received no fertilizer in the experimental period. Natural N-15 abundance techniques were used to determine pea N-2 fixation. The pea-barley intercrop yielded 4.0 Mg grain ha(-1), which was about 0.5 Mg lower than the yields of sole cropped pea but about 1.5 Mg greater than harvested......, there was no significant difference between the subsequent non-fertilized winter-rye grain yields averaging 2.8 Mg ha(-1), indicating an equalization of the quality of incorporated residue by the NO3- leaching pattern. NO3- leaching throughout the experimental period was 61 to 76 kg N ha(-1). Leaching dynamics indicated...

  13. 77 FR 23369 - Federal Acquisition Regulation; Justification and Approval of Sole-Source 8(a) Contracts

    Science.gov (United States)

    2012-04-18

    ... Business Administration (SBA) may not accept a sole- source 8(a) contract in excess of $20 million for... is no conflict with the law. Execution of the J&A prior to the SBA's initiation of contract... small number of businesses that have been awarded 8(a) contracts over the $20 million threshold may be...

  14. Use of thermography to monitor sole haemorrhages and temperature distribution over the claws of dairy cattle.

    Science.gov (United States)

    Wilhelm, K; Wilhelm, J; Fürll, M

    2015-02-07

    Subclinical laminitis, an early pathological event in the development of many claw diseases, is an important factor in the welfare and economics of high-producing dairy cows. However, the aetiology and pathogenesis of this complex claw disease are not well understood. The present study investigated to what extent thermographic examination of claws is able to give information about corium inflammation, and whether the technique may be used as a diagnostic tool for early detection of subclinical laminitis. Moreover, the temperature distribution over the individual main claws was investigated to obtain further knowledge about pressure distribution on the claws. For this purpose the claws of 123 cows were evaluated in the first week after calving as well as after the second month of lactation for presence of sole haemorrhages (a sign of subclinical laminitis). Furthermore, the ground contact area was analysed by thermography. Sole haemorrhages were significantly increased by the second month of lactation. Thermography showed clear differences between the claws of the front limbs and hindlimbs, as well as between lateral and medial claws. Although the distribution of sole haemorrhages was consistent with the pattern of the temperature distribution over the main claws, no clear correlation was found between the claw temperature after calving and the visible laminitis-like changes (sole haemorrhages) eight weeks later. British Veterinary Association.

  15. A Mole in the Sole: Case Report on Eccrine Poroma | Das | Internet ...

    African Journals Online (AJOL)

    Eccrine poroma is a benign tumor which arises from the intraepidermal portion of the eccrine sweat glands. 81 year old diabetic grandma worried about her persistently uncontrolled blood sugar owing to a painless mole in the sole of right foot for 2 years. Excisional biopsy revealed a sweat duct benign eccrine poroma.

  16. Sole disorders in conventionally managed and organic dairy herds using different housing systems

    DEFF Research Database (Denmark)

    Vaarst, Mette; Hindhede, Jens; Enevoldsen, Carsten

    1998-01-01

    Records of claw trimmings were analyzed in seven organic and six conventional Danish herds (a total of 974 cows). The housing systems represented were tie stall systems, loose housing system with slatted floor (one organic herd), and deep litter systems (deep straw bedding). Occurrence of sole...

  17. Effects of climate change on growth of 0-group sole and plaice

    NARCIS (Netherlands)

    Teal, L.R.; Leeuw, de J.J.; Veer, van der H.W.; Rijnsdorp, A.D.

    2008-01-01

    The effect of rising seawater temperature on growth of 0-group sole Solea solea and plaice Pleuronectes platessa in the southeastern North Sea was investigated for the period 1970 to 2004 using annual autumn pre-recruit survey data and frequent surveys on a nursery ground. Autumn length showed an

  18. Learning of Chemical Equilibrium through Modelling-Based Teaching

    Science.gov (United States)

    Maia, Poliana Flavia; Justi, Rosaria

    2009-01-01

    This paper presents and discusses students' learning process of chemical equilibrium from a modelling-based approach developed from the use of the "Model of Modelling" diagram. The investigation was conducted in a regular classroom (students 14-15 years old) and aimed at discussing how modelling-based teaching can contribute to students…

  19. Stimulating Scientific Reasoning with Drawing-Based Modeling

    Science.gov (United States)

    Heijnes, Dewi; van Joolingen, Wouter; Leenaars, Frank

    2018-01-01

    We investigate the way students' reasoning about evolution can be supported by drawing-based modeling. We modified the drawing-based modeling tool SimSketch to allow for modeling evolutionary processes. In three iterations of development and testing, students in lower secondary education worked on creating an evolutionary model. After each…

  20. Computer Profiling Based Model for Investigation

    OpenAIRE

    Neeraj Choudhary; Nikhil Kumar Singh; Parmalik Singh

    2011-01-01

    Computer profiling is used for computer forensic analysis, and proposes and elaborates on a novel model for use in computer profiling, the computer profiling object model. The computer profiling object model is an information model which models a computer as objects with various attributes and inter-relationships. These together provide the information necessary for a human investigator or an automated reasoning engine to make judgments as to the probable usage and evidentiary value of a comp...

  1. Performance Measurement Model A TarBase model with ...

    Indian Academy of Sciences (India)

    rohit

    Model A 8.0 2.0 94.52% 88.46% 76 108 12 12 0.86 0.91 0.78 0.94. Model B 2.0 2.0 93.18% 89.33% 64 95 10 9 0.88 0.90 0.75 0.98. The above results for TEST – 1 show details for our two models (Model A and Model B).Performance of Model A after adding of 32 negative dataset of MiRTif on our testing set(MiRecords) ...

  2. Neuronal control of pedal sole cilia in the pond snail Lymnaea stagnalis appressa.

    Science.gov (United States)

    Longley, Roger D; Peterman, Misa

    2013-01-01

    5-HT (serotonin) is a ubiquitous neurotransmitter that produces ciliary beating in gastropods when applied topically, but ciliary beating caused by gastropod serotonergic neurons has been described in only three neuron pairs. We extend these results to the North American Lymnaea stagnalis appressa, which is a different species from the European Lymnaea stagnalis. We describe a non-serotonergic neuron pair, PeV1, which accelerates pedal sole mucociliary transport and a serotonergic neuron pair, PeD7, which slows mucociliary transport. We compare and discuss development and identified neurons in L. s. appressa and in L. stagnalis, which have homologs to L. s. appressa PeD7 and PeV1 neurons. In addition to PeD7 and PeV1 neurons, we test neurons immunoreactive to Tritonia pedal peptide antibodies with negative results for mucociliary transport. In characterizing PeD7 and PeV1 neurons, we find that PeV1 does not excite PeD7. In semi-intact preparations, a strong increase in PeD7 neuron activity occurs during tactile stimulation, but V1 neurons are inhibited during tactile stimulation. Following tactile stimulation, PeV1 neurons show strong activity. This suggests a distinct difference in function of the two neuron pairs, which both have their axons overlying pedal sole ciliary cells. Application of 5-HT to the pedal sole initiates mucociliary transport in 1.4-1.9 s with a time course similar to that seen when stimulating a PeV1 neuron. This result appears to be through a 5-HT(1A)-like receptor on the pedal sole. We describe a possible external source of 5-HT on the pedal sole from 5-HT immunoreactive granules that are released with mucus.

  3. Pilot Testing of a Sampling Methodology for Assessing Seed Attachment Propensity and Transport Rate in a Soil Matrix Carried on Boot Soles and Bike Tires.

    Science.gov (United States)

    Hardiman, Nigel; Dietz, Kristina Charlotte; Bride, Ian; Passfield, Louis

    2017-01-01

    Land managers of natural areas are under pressure to balance demands for increased recreation access with protection of the natural resource. Unintended dispersal of seeds by visitors to natural areas has high potential for weedy plant invasions, with initial seed attachment an important step in the dispersal process. Although walking and mountain biking are popular nature-based recreation activities, there are few studies quantifying propensity for seed attachment and transport rate on boot soles and none for bike tires. Attachment and transport rate can potentially be affected by a wide range of factors for which field testing can be time-consuming and expensive. We pilot tested a sampling methodology for measuring seed attachment and transport rate in a soil matrix carried on boot soles and bike tires traversing a known quantity and density of a seed analog (beads) over different distances and soil conditions. We found % attachment rate on boot soles was much lower overall than previously reported, but that boot soles had a higher propensity for seed attachment than bike tires in almost all conditions. We believe our methodology offers a cost-effective option for researchers seeking to manipulate and test effects of different influencing factors on these two dispersal vectors.

  4. A Self-Adaptive Model-Based Wi-Fi Indoor Localization Method.

    Science.gov (United States)

    Tuta, Jure; Juric, Matjaz B

    2016-12-06

    This paper presents a novel method for indoor localization, developed with the main aim of making it useful for real-world deployments. Many indoor localization methods exist, yet they have several disadvantages in real-world deployments-some are static, which is not suitable for long-term usage; some require costly human recalibration procedures; and others require special hardware such as Wi-Fi anchors and transponders. Our method is self-calibrating and self-adaptive thus maintenance free and based on Wi-Fi only. We have employed two well-known propagation models-free space path loss and ITU models-which we have extended with additional parameters for better propagation simulation. Our self-calibrating procedure utilizes one propagation model to infer parameters of the space and the other to simulate the propagation of the signal without requiring any additional hardware beside Wi-Fi access points, which is suitable for real-world usage. Our method is also one of the few model-based Wi-Fi only self-adaptive approaches that do not require the mobile terminal to be in the access-point mode. The only input requirements of the method are Wi-Fi access point positions, and positions and properties of the walls. Our method has been evaluated in single- and multi-room environments, with measured mean error of 2-3 and 3-4 m, respectively, which is similar to existing methods. The evaluation has proven that usable localization accuracy can be achieved in real-world environments solely by the proposed Wi-Fi method that relies on simple hardware and software requirements.

  5. Influence of vegetable diets on physiological and immune responses to thermal stress in Senegalese sole (Solea senegalensis)

    DEFF Research Database (Denmark)

    Conde-Sieira, Marta; Gesto, Manuel; Batista, Sónia

    2018-01-01

    quality parameters. However, scarce information is available regarding the long-term impact of vegetable diets (combining the inclusion of both vegetable protein and oils) on the stress response and immunity of this fish species. This study aims to evaluate the concomitant effect of the extended use...... of vegetable protein-based diets with fish oil (FO) replacement (0, 50 or 100%) by vegetable oils (VO), on the response to acute (10 min) or prolonged (4 days) stress, induced by thermal shock. Plasma levels of cortisol, glucose and lactate as well as hepatic levels of glucose, glycogen and lactate were......The substitution of fish resources as ingredients for aquafeeds by those based on vegetable sources is needed to ensure aquaculture sustainability in the future. It is known that Senegalese sole (Solea senegalensis) accepts high dietary content of plant ingredients without altering growth or flesh...

  6. Model-Based Requirements Management in Gear Systems Design Based On Graph-Based Design Languages

    Directory of Open Access Journals (Sweden)

    Kevin Holder

    2017-10-01

    Full Text Available For several decades, a wide-spread consensus concerning the enormous importance of an in-depth clarification of the specifications of a product has been observed. A weak clarification of specifications is repeatedly listed as a main cause for the failure of product development projects. Requirements, which can be defined as the purpose, goals, constraints, and criteria associated with a product development project, play a central role in the clarification of specifications. The collection of activities which ensure that requirements are identified, documented, maintained, communicated, and traced throughout the life cycle of a system, product, or service can be referred to as “requirements engineering”. These activities can be supported by a collection and combination of strategies, methods, and tools which are appropriate for the clarification of specifications. Numerous publications describe the strategy and the components of requirements management. Furthermore, recent research investigates its industrial application. Simultaneously, promising developments of graph-based design languages for a holistic digital representation of the product life cycle are presented. Current developments realize graph-based languages by the diagrams of the Unified Modelling Language (UML, and allow the automatic generation and evaluation of multiple product variants. The research presented in this paper seeks to present a method in order to combine the advantages of a conscious requirements management process and graph-based design languages. Consequently, the main objective of this paper is the investigation of a model-based integration of requirements in a product development process by means of graph-based design languages. The research method is based on an in-depth analysis of an exemplary industrial product development, a gear system for so-called “Electrical Multiple Units” (EMU. Important requirements were abstracted from a gear system

  7. Model Based Analysis and Test Generation for Flight Software

    Science.gov (United States)

    Pasareanu, Corina S.; Schumann, Johann M.; Mehlitz, Peter C.; Lowry, Mike R.; Karsai, Gabor; Nine, Harmon; Neema, Sandeep

    2009-01-01

    We describe a framework for model-based analysis and test case generation in the context of a heterogeneous model-based development paradigm that uses and combines Math- Works and UML 2.0 models and the associated code generation tools. This paradigm poses novel challenges to analysis and test case generation that, to the best of our knowledge, have not been addressed before. The framework is based on a common intermediate representation for different modeling formalisms and leverages and extends model checking and symbolic execution tools for model analysis and test case generation, respectively. We discuss the application of our framework to software models for a NASA flight mission.

  8. Supply based on demand dynamical model

    Science.gov (United States)

    Levi, Asaf; Sabuco, Juan; Sanjuán, Miguel A. F.

    2018-04-01

    We propose and numerically analyze a simple dynamical model that describes the firm behaviors under uncertainty of demand. Iterating this simple model and varying some parameter values, we observe a wide variety of market dynamics such as equilibria, periodic, and chaotic behaviors. Interestingly, the model is also able to reproduce market collapses.

  9. Cognitive components underpinning the development of model-based learning.

    Science.gov (United States)

    Potter, Tracey C S; Bryce, Nessa V; Hartley, Catherine A

    2017-06-01

    Reinforcement learning theory distinguishes "model-free" learning, which fosters reflexive repetition of previously rewarded actions, from "model-based" learning, which recruits a mental model of the environment to flexibly select goal-directed actions. Whereas model-free learning is evident across development, recruitment of model-based learning appears to increase with age. However, the cognitive processes underlying the development of model-based learning remain poorly characterized. Here, we examined whether age-related differences in cognitive processes underlying the construction and flexible recruitment of mental models predict developmental increases in model-based choice. In a cohort of participants aged 9-25, we examined whether the abilities to infer sequential regularities in the environment ("statistical learning"), maintain information in an active state ("working memory") and integrate distant concepts to solve problems ("fluid reasoning") predicted age-related improvements in model-based choice. We found that age-related improvements in statistical learning performance did not mediate the relationship between age and model-based choice. Ceiling performance on our working memory assay prevented examination of its contribution to model-based learning. However, age-related improvements in fluid reasoning statistically mediated the developmental increase in the recruitment of a model-based strategy. These findings suggest that gradual development of fluid reasoning may be a critical component process underlying the emergence of model-based learning. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

  10. Histopathological and morphometric studies on the hooves of dairy and beef cattle in relation to overgrown sole and laminitis.

    Science.gov (United States)

    Singh, S S; Murray, R D; Ward, W R

    1992-10-01

    In dairy cattle, histopathology of the outer hind claws with overgrown sole revealed arteriosclerosis of blood vessels at the ulcer site in the sole. The laminae did not show any hyperplasia of the epidermis and thrombi were not seen in the blood vessels. Partial or complete disappearance of onychogenic substance was observed in the sole as well as in the wall epidermis. In beef animals, typical changes suggestive of chronic laminitis were seen: these included hyperplasia of the epidermis of the laminae, thrombus formation, arteriosclerosis in the corium of the sole, the abaxial wall and the coronary corium. Morphometric analysis quantified measurements of hooves of normal, beef and dairy cattle. It may be concluded that the changes associated with overgrowth of the sole in dairy cattle are localized to the sole without involvement of the laminae and that the term laminitis is not appropriate in the condition seen in dairy cattle.

  11. New Temperature-based Models for Predicting Global Solar Radiation

    International Nuclear Information System (INIS)

    Hassan, Gasser E.; Youssef, M. Elsayed; Mohamed, Zahraa E.; Ali, Mohamed A.; Hanafy, Ahmed A.

    2016-01-01

    Highlights: • New temperature-based models for estimating solar radiation are investigated. • The models are validated against 20-years measured data of global solar radiation. • The new temperature-based model shows the best performance for coastal sites. • The new temperature-based model is more accurate than the sunshine-based models. • The new model is highly applicable with weather temperature forecast techniques. - Abstract: This study presents new ambient-temperature-based models for estimating global solar radiation as alternatives to the widely used sunshine-based models owing to the unavailability of sunshine data at all locations around the world. Seventeen new temperature-based models are established, validated and compared with other three models proposed in the literature (the Annandale, Allen and Goodin models) to estimate the monthly average daily global solar radiation on a horizontal surface. These models are developed using a 20-year measured dataset of global solar radiation for the case study location (Lat. 30°51′N and long. 29°34′E), and then, the general formulae of the newly suggested models are examined for ten different locations around Egypt. Moreover, the local formulae for the models are established and validated for two coastal locations where the general formulae give inaccurate predictions. Mostly common statistical errors are utilized to evaluate the performance of these models and identify the most accurate model. The obtained results show that the local formula for the most accurate new model provides good predictions for global solar radiation at different locations, especially at coastal sites. Moreover, the local and general formulas of the most accurate temperature-based model also perform better than the two most accurate sunshine-based models from the literature. The quick and accurate estimations of the global solar radiation using this approach can be employed in the design and evaluation of performance for

  12. Probing of brain states in real-time: Introducing the ConSole environment

    Directory of Open Access Journals (Sweden)

    Thomas eHartmann

    2011-03-01

    Full Text Available Recent years have seen huge advancements in the methods available and used in neuroscience employing EEG or MEG. However, the standard approach is to average a large number of trials for experimentally defined conditions in order to reduce intertrial-variability, i.e. treating it as a source of "noise". Yet it is now more and more accepted that trial-to-trial fluctuations bear functional significance, reflecting fluctuations of "brain states" that predispose perception and action. Such effects are often revealed in a pre-stimulus period, when comparing response variability to an invariant stimulus. However such offline analyses are disadvantageous as they are correlational by drawing conclusions in a posthoc-manner and stimulus presentation is random with respect to the feature of interest. A more direct test is to trigger stimulus presentation when the relevant feature is present. The current paper introduces ConSole (CONstance System for OnLine Eeg, a software package capable of analyzing ongoing EEG / MEG in real-time and presenting auditory and visual stimuli via internal routines. Stimulation via external devices (e.g. TMS or third-party software (e.g. Psyscope X is possible by sending TTL-triggers. With ConSole it is thus possible to target the stimulation at specific brain-states. In contrast to many available applications, ConSole is open-source. Its modular design enhances the power of the software as it can be easily adapted to new challenges and writing new experiments is an easy task. ConSole is already pre-equipped with modules performing standard signal processing steps. The software is also independent from the EEG / MEG system, as long as a driver can be written (currently 2 EEG systems are supported. Besides a general introduction, we present benchmark data regarding performance and validity of the calculations used, as well as three example applications of ConSole in different settings. ConSole can be downloaded at: http://console-kn.sf.net.

  13. Stochastic Wake Modelling Based on POD Analysis

    Directory of Open Access Journals (Sweden)

    David Bastine

    2018-03-01

    Full Text Available In this work, large eddy simulation data is analysed to investigate a new stochastic modeling approach for the wake of a wind turbine. The data is generated by the large eddy simulation (LES model PALM combined with an actuator disk with rotation representing the turbine. After applying a proper orthogonal decomposition (POD, three different stochastic models for the weighting coefficients of the POD modes are deduced resulting in three different wake models. Their performance is investigated mainly on the basis of aeroelastic simulations of a wind turbine in the wake. Three different load cases and their statistical characteristics are compared for the original LES, truncated PODs and the stochastic wake models including different numbers of POD modes. It is shown that approximately six POD modes are enough to capture the load dynamics on large temporal scales. Modeling the weighting coefficients as independent stochastic processes leads to similar load characteristics as in the case of the truncated POD. To complete this simplified wake description, we show evidence that the small-scale dynamics can be captured by adding to our model a homogeneous turbulent field. In this way, we present a procedure to derive stochastic wake models from costly computational fluid dynamics (CFD calculations or elaborated experimental investigations. These numerically efficient models provide the added value of possible long-term studies. Depending on the aspects of interest, different minimalized models may be obtained.

  14. Modeling and simulation of complex systems a framework for efficient agent-based modeling and simulation

    CERN Document Server

    Siegfried, Robert

    2014-01-01

    Robert Siegfried presents a framework for efficient agent-based modeling and simulation of complex systems. He compares different approaches for describing structure and dynamics of agent-based models in detail. Based on this evaluation the author introduces the "General Reference Model for Agent-based Modeling and Simulation" (GRAMS). Furthermore he presents parallel and distributed simulation approaches for execution of agent-based models -from small scale to very large scale. The author shows how agent-based models may be executed by different simulation engines that utilize underlying hard

  15. On Process Modelling Using Physical Oriented And Phenomena Based Principles

    Directory of Open Access Journals (Sweden)

    Mihai Culea

    2000-12-01

    Full Text Available This work presents a modelling framework based on phenomena description of the process. The approach is taken to easy understand and construct process model in heterogeneous possible distributed modelling and simulation environments. A simplified case study of a heat exchanger is considered and Modelica modelling language to check the proposed concept. The partial results are promising and the research effort will be extended in a computer aided modelling environment based on phenomena.

  16. Implementing model based systems engineering in South Africa

    CSIR Research Space (South Africa)

    Oosthuizen, Rudolph

    2017-10-01

    Full Text Available and validation activities beginning in the conceptual design phase and continuing throughout development and later life cycle phases”. Model-Based Systems Engineering (MBSE) employs modelling languages, such as Systems Modelling Language (SysML) or Unified...). Model Based Systems Engineering General Concepts MBSE is defined as the formalized application of modeling to support system requirements, design, analysis, verification and validation activities throughout the system life cycle phases (Gau...

  17. Molecular Method for Sex Identification of Half-Smooth Tongue Sole (Cynoglossus semilaevis Using a Novel Sex-Linked Microsatellite Marker

    Directory of Open Access Journals (Sweden)

    Xiaolin Liao

    2014-07-01

    Full Text Available Half-smooth tongue sole (Cynoglossus semilaevis is one of the most important flatfish species for aquaculture in China. To produce a monosex population, we attempted to develop a marker-assisted sex control technique in this sexually size dimorphic fish. In this study, we identified a co-dominant sex-linked marker (i.e., CyseSLM by screening genomic microsatellites and further developed a novel molecular method for sex identification in the tongue sole. CyseSLM has a sequence similarity of 73%–75% with stickleback, medaka, Fugu and Tetraodon. At this locus, two alleles (i.e., A244 and A234 were amplified from 119 tongue sole individuals with primer pairs CyseSLM-F1 and CyseSLM-R. Allele A244 was present in all individuals, while allele A234 (female-associated allele, FAA was mostly present in females with exceptions in four male individuals. Compared with the sequence of A244, A234 has a 10-bp deletion and 28 SNPs. A specific primer (CyseSLM-F2 was then designed based on the A234 sequence, which amplified a 204 bp fragment in all females and four males with primer CyseSLM-R. A time-efficient multiplex PCR program was developed using primers CyseSLM-F2, CyseSLM-R and the newly designed primer CyseSLM-F3. The multiplex PCR products with co-dominant pattern could be detected by agarose gel electrophoresis, which accurately identified the genetic sex of the tongue sole. Therefore, we have developed a rapid and reliable method for sex identification in tongue sole with a newly identified sex-linked microsatellite marker.

  18. Effects of de-oiled palm kernel cake based fertilizers on sole maize ...

    African Journals Online (AJOL)

    AJL

    2012-03-08

    Mar 8, 2012 ... conventional fertilizers. Nutritional values of the two crops were raised by the application of the fertilizer formulations. Key words: De-oiled seed cake, palm kernel, fertilizer. INTRODUCTION. De-oiled seed cake (Doc) is a by product of oil seed from oil extraction plants. It has the potential of being used as.

  19. Determination of the electromagnetic character of soft dipole modes solely based on quasicontinuous γ spectroscopy

    International Nuclear Information System (INIS)

    Voinov, A.; Schiller, A.; Guttormsen, M.; Rekstad, J.; Siem, S.

    2003-01-01

    We show that the combined analysis of quasicontinuous γ spectra from the ( 3 He,α) and (n th ,2γ) reactions gives the possibility to measure the electromagnetic character of soft dipole resonances. Two-step γ-cascade spectra have been calculated, using level densities and radiative strength functions from the ( 3 He,αγ) reaction. The calculations show that the intensity of the two-step cascades depends on the electromagnetic character of the soft dipole resonance under study. The difference reaches 40-100% which can be measured experimentally

  20. Benchmarking model-free and model-based optimal control

    NARCIS (Netherlands)

    Koryakovskiy, I.; Kudruss, M.; Babuska, R.; Caarls, W.; Kirches, Christian; Mombaur, Katja; Schlöder, Johannes P.; Vallery, H.

    2017-01-01

    Model-free reinforcement learning and nonlinear model predictive control are two different approaches for controlling a dynamic system in an optimal way according to a prescribed cost function. Reinforcement learning acquires a control policy through exploratory interaction with the system, while

  1. Tree-Based Global Model Tests for Polytomous Rasch Models

    Science.gov (United States)

    Komboz, Basil; Strobl, Carolin; Zeileis, Achim

    2018-01-01

    Psychometric measurement models are only valid if measurement invariance holds between test takers of different groups. Global model tests, such as the well-established likelihood ratio (LR) test, are sensitive to violations of measurement invariance, such as differential item functioning and differential step functioning. However, these…

  2. Performance Measurement Model A TarBase model with ...

    Indian Academy of Sciences (India)

    rohit

    Cost. G=Gamma. CV=Cross Validation. MCC=Matthew Correlation Coefficient. Test 1: C G CV Accuracy TP TN FP FN ... Conclusion: Without considering the MirTif negative dataset for training Model A and B classifiers, our Model A and B ...

  3. A Size-based Ecosystem Model

    DEFF Research Database (Denmark)

    Ravn-Jonsen, Lars

     Ecosystem Management requires models that can link the ecosystem level to the operation level. This link can be created by an ecosystem production model. Because the function of the individual fish in the marine ecosystem, seen in trophic context, is closely related to its size, the model groups...... fish according to size. The model summarises individual predation events into ecosystem level properties, and thereby uses the law of conversation of mass as a framework. This paper provides the background, the conceptual model, basic assumptions, integration of fishing activities, mathematical...... the predator--prey interaction, (ii) mass balance in the predator--prey allocation, and (iii) mortality and somatic growth as a consequence of the predator--prey allocation. By incorporating additional assumptions, the model can be extended to other dimensions of the ecosystem, for example, space or species...

  4. Agent Based Reasoning in Multilevel Flow Modeling

    DEFF Research Database (Denmark)

    Lind, Morten; Zhang, Xinxin

    2012-01-01

    to launch the MFM Workbench into an agent based environment, which can complement disadvantages of the original software. The agent-based MFM Workbench is centered on a concept called “Blackboard System” and use an event based mechanism to arrange the reasoning tasks. This design will support the new...

  5. Model-based software process improvement

    Science.gov (United States)

    Zettervall, Brenda T.

    1994-01-01

    The activities of a field test site for the Software Engineering Institute's software process definition project are discussed. Products tested included the improvement model itself, descriptive modeling techniques, the CMM level 2 framework document, and the use of process definition guidelines and templates. The software process improvement model represents a five stage cyclic approach for organizational process improvement. The cycles consist of the initiating, diagnosing, establishing, acting, and leveraging phases.

  6. Integrating Effects-Based and Attrition-Based Modeling

    National Research Council Canada - National Science Library

    DeGregorio, Edward A; Janssen, Raymond A; Wagenhals, Lee W; Messier, Richard H

    2004-01-01

    .... Modeling the NCW EBO process attempts to codify the belief structure and reasoning of adversaries and their cause-effect relationships with US and coalition actions, including mitigating undesired effects...

  7. Regression model for the study of sole and cumulative effect of ...

    African Journals Online (AJOL)

    Jane

    2011-08-17

    Aug 17, 2011 ... (PW2), sowing was recommended at this time period for yield sustainability in rainfed agriculture. Solar radiation is an important environmental factor that brings positive changes in the crop growth by altering leaf architecture and light partitioning. Similarly, solar radiation activates the photosystem by which ...

  8. Research on the Integration of Bionic Geometry Modeling and Simulation of Robot Foot Based on Characteristic Curve

    Science.gov (United States)

    He, G.; Zhu, H.; Xu, J.; Gao, K.; Zhu, D.

    2017-09-01

    The bionic research of shape is an important aspect of the research on bionic robot, and its implementation cannot be separated from the shape modeling and numerical simulation of the bionic object, which is tedious and time-consuming. In order to improve the efficiency of shape bionic design, the feet of animals living in soft soil and swamp environment are taken as bionic objects, and characteristic skeleton curve, section curve, joint rotation variable, position and other parameters are used to describe the shape and position information of bionic object’s sole, toes and flipper. The geometry modeling of the bionic object is established by using the parameterization of characteristic curves and variables. Based on this, the integration framework of parametric modeling and finite element modeling, dynamic analysis and post-processing of sinking process in soil is proposed in this paper. The examples of bionic ostrich foot and bionic duck foot are also given. The parametric modeling and integration technique can achieve rapid improved design based on bionic object, and it can also greatly improve the efficiency and quality of robot foot bionic design, and has important practical significance to improve the level of bionic design of robot foot’s shape and structure.

  9. Bootstrap confidence intervals for model-based surveys | Ouma ...

    African Journals Online (AJOL)

    To deal with the problem, Chambers and Dorfam (1994) suggested a n alternative method based on the bootstrap methodology. Their method is meant for model-based surveys. It starts by assuming a simple linear regression model as a working model in which the ratio estimator is optimal for estimating the population total.

  10. Biglan Model Test Based on Institutional Diversity.

    Science.gov (United States)

    Roskens, Ronald W.; Creswell, John W.

    The Biglan model, a theoretical framework for empirically examining the differences among subject areas, classifies according to three dimensions: adherence to common set of paradigms (hard or soft), application orientation (pure or applied), and emphasis on living systems (life or nonlife). Tests of the model are reviewed, and a further test is…

  11. Modeling rule-based item generation

    NARCIS (Netherlands)

    Geerlings, Hanneke; Glas, Cornelis A.W.; van der Linden, Willem J.

    2011-01-01

    An application of a hierarchical IRT model for items in families generated through the application of different combinations of design rules is discussed. Within the families, the items are assumed to differ only in surface features. The parameters of the model are estimated in a Bayesian framework,

  12. Click Model-Based Information Retrieval Metrics

    NARCIS (Netherlands)

    Chuklin, A.; Serdyukov, P.; de Rijke, M.

    2013-01-01

    In recent years many models have been proposed that are aimed at predicting clicks of web search users. In addition, some information retrieval evaluation metrics have been built on top of a user model. In this paper we bring these two directions together and propose a common approach to converting

  13. Model Based Analysis of Insider Threats

    DEFF Research Database (Denmark)

    Chen, Taolue; Han, Tingting; Kammueller, Florian

    2016-01-01

    In order to detect malicious insider attacks it is important to model and analyse infrastructures and policies of organisations and the insiders acting within them. We extend formal approaches that allow modelling such scenarios by quantitative aspects to enable a precise analysis of security...

  14. Feed intake as explanation for density related growth differences of common sole Solea solea

    DEFF Research Database (Denmark)

    Lund, Ivar; Steenfeldt, Svend Jørgen; Herrmann, Bent

    2013-01-01

    correlated to both fish size and individual SGR. Feed conversion ratio was likewise positively correlated to feed intake. The relative feed intake (g feed g fish−1) was not correlated to fish size at any density tested, but was significantly highest for the LD population. This explains a substantial part......Growth of common sole Solea solea is negatively correlated to density, which affects productivity in culture and hence commercial success. Studies of individual feed intake were performed to examine growth and population dynamics at different densities. Three initial stocking densities: 1.0, 2.......1 and 3.9 kg m−2 of individually tagged sole, referred to as low density (LD), medium density and high density HD), were examined during 145 days. Despite that tank productivity (g m−2 day−1), was highest for the HD group, the specific growth rate (SGR) decreased significantly with increase in stocking...

  15. Acetate as Sole Carbon and Energy Source for Growth of Methanosarcina Strain 227

    OpenAIRE

    Smith, Michael R.; Mah, Robert A.

    1980-01-01

    Methanosarcina strain 227 grew rapidly and produced methane on a mineral medium containing acetate as the sole added organic substrate. Cell yields but not doubling times were affected by the presence or absence of yeast extract. Greater cell yields occurred in yeast extract medium than in mineral medium. Radioactive labeling studies showed that acetate was decarboxylated in mineral medium, as was shown previously in complex medium. The specific radioactivity of methane produced per specific ...

  16. Sensory and aromatic characteristics of tongue sole by-products hydrolysates (Cynoglossus senegalensis)

    OpenAIRE

    Sylla, K. S. B.; Berge, Jean-pascal; Prost, Carole; Musabyemariya, B.; Seydi, Mg

    2009-01-01

    Tongue sole by-products coming from fish-filleting plant were hydrolyzed by Protamex® protease. To identify the future application of hydrolysates, a sensory analysis was carried out.The sensory profile was performed with a jury of 14 specialized judges.11 profiles were found by this panel of tasting. In addition, the aromatic characterization revealed that 57 molecules are responsible for these odours described in sensory analysis.The description of these aromatic compounds opens potentia...

  17. Distribution and transport patterns of northern rock sole, Lepidopsetta polyxystra, larvae in the southeastern Bering Sea

    Science.gov (United States)

    Lanksbury, Jennifer A.; Duffy-Anderson, Janet T.; Mier, Kathryn L.; Busby, Morgan S.; Stabeno, Phyllis J.

    2007-01-01

    We report the size, abundance, and distribution (horizontal, vertical) of northern rock sole, Lepidopsetta polyxystra, larvae collected from ichthyoplankton surveys on the southeastern Bering Sea shelf near Unimak Island, in Unimak Pass, and in the Gulf of Alaska south of Unimak Island. The greatest abundances of larvae occurred within Unimak Pass and in the Bering Sea northeast of Unimak Island. Larvae were smaller and more abundant in 2002 than in 2003. Larval abundance and size varied with depth. Highest abundances were at depths of 10-30 m during the day, and larger fish appeared to migrate from below 20 m to 0-10 m at night. There was evidence of multiple spawning locales and larval dispersal pathways that were depth- and area-specific. Northern rock sole larvae spawned west of Unimak Pass along the Aleutian Islands may be transported northward by the Bering Slope Current. Larvae spawned in the Gulf of Alaska and advected through Unimak Pass are differentially dispersed, primarily to the middle and outer shelves along the 100 m and 200 m isobaths, or along the Alaska Peninsula. Larvae spawned along the Alaska Peninsula east of Unimak Island appear to have the greatest chance of being transported to nursery areas in the coastal domain. Dispersal of near-surface northern rock sole larvae in any of these locations is likely influenced by wind-driven advection, but below-surface (>10 m) northern rock sole larval transport is probably more affected by factors that modulate geostrophic flow rather than wind-driven surface currents.

  18. Onset of obsessive compulsive disorder in pregnancy with pica as the sole manifestation

    OpenAIRE

    Suneet Kumar Upadhyaya; Archana Sharma

    2012-01-01

    Pica refers to eating of non-nutritious substances, which is usually seen in childhood or pregnancy. Here we report a case of an illiterate tribal woman who developed pica as the sole manifestation of obsessive compulsive disorder, with onset during pregnancy. The patient had compulsions of eating uncooked rice or wheat, which resulted in toothache and abdominal discomfort. She had this habit in three pregnancies, consecutively. In the first two pregnancies it resolved spontaneously after pue...

  19. Towards surface analysis on diabetic feet soles to predict ulcerations using photometric stereo

    Science.gov (United States)

    Liu, Chanjuan; van der Heijden, Ferdi; van Netten, Jaap J.

    2012-03-01

    Diabetic foot ulceration is a major complication for patients with diabetes mellitus. Approximately 15% to 25% of patients with Type I and Type II diabetes eventually develop feet ulcers. If not adequately treated, these ulcers may lead to foot infection, and ultimately to total (or partial) lower extremity amputation, which means a great loss in health-related quality of life. The incidence of foot ulcers may be prevented by early identification and subsequent treatment of pre-signs of ulceration, such as callus formation, redness, fissures, and blisters. Therefore, frequent examination of the feet is necessary, preferably on a daily basis. However, self-examination is difficult or impossible due to consequences of the diabetes. Moreover, frequent examination by health care professionals is costly and not feasible. The objective of our project is to develop an intelligent telemedicine monitoring system that can be deployed at the patients' home environment for frequent examination of patients feet, to timely detect pre-signs of ulceration. The current paper reports the preliminary results of an implementation of a photometric stereo imaging system to detect 3D geometric abnormalities of the skin surfaces of foot soles. Using a flexible experimental setup, the system parameters such as number and positions of the illuminators have been selected so as to optimize the performance with respect to reconstructed surface. The system has been applied to a dummy foot sole. Finally, the curvature on the resulting 3D topography of the foot sole is implemented to show the feasibility of detecting the pre-signs of ulceration using photometric stereo imaging. The obtained results indicate clinical potential of this technology for detecting the pre-signs of ulceration on diabetic feet soles.

  20. Single Locus Maintains Large Variation of Sex Reversal in Half-Smooth Tongue Sole (Cynoglossus semilaevis)

    OpenAIRE

    Jiang, Li; Li, Hengde

    2016-01-01

    Sex determination is a fundamental biological process for individual sex development and population sex ratios. However, for some species, the primary sex might be altered during development, and individuals can develop into the opposite sex. Sex reversal may happen in insects, reptiles, amphibians, and fishes. In half-smooth tongue sole (Cynoglossus semilaevis), some genetically female fish irreversibly reverse to pseudomales, resulting in higher costs in aquaculture owing to a lower growth ...

  1. Studies in cross-linking PVC footwear soling compounds using gamma-irradiation

    International Nuclear Information System (INIS)

    Bloom, L.I.

    1983-01-01

    Irradiation cross-linking of polymeric materials has been known for some time, but it is only in recent years that it has been put to commercial advantage. Well known uses are the modification of PVC for higher temperature applications. Fundamental studies were carried out on amongst other materials, plasticised PVC compounds for use in cable applications. The results of this work, encouraged the author to investigate cross-linkable PVC in areas such as footwear soling

  2. The effects of grading on the growth and survival of juvenile Dover sole (Solea solea L)

    DEFF Research Database (Denmark)

    Overton, Julia Lynne; Steenfeldt, Svend Jørgen; Pedersen, Per Bovbjerg

    2010-01-01

    A 3-month study was carried out to investigate the effects of grading on the overall production, growth performance and survival of juvenile Dover sole (Solea solea L.). Juvenile fish (4.0–40.4 g) were sorted into three size groups: small (4.0–15.5 g), medium (16.0–21.5 g) and large (22.0–40.5 g)...

  3. Tiny intracranial aneurysms: Endovascular treatment by coil embolisation or sole stent deployment

    International Nuclear Information System (INIS)

    Lu Jun; Liu Jiachun; Wang Lijun; Qi Peng; Wang Daming

    2012-01-01

    Purpose: Tiny intracranial aneurysms pose a significant therapeutic challenge for interventional neuroradiologists. The authors report their preliminary results of endovascular treatment of these aneurysms. Methods: Between January 2002 and December 2009, 52 tiny intracranial aneurysms (defined as ≤3 mm in maximum diameter) in 46 patients (22 men; mean age, 57.9 years) were treated by endosaccular coil embolisation or sole stent deployment in the parent artery. Of 52 aneurysms, 29 had ruptured and 23 remained unruptured. The initial angiographic results, procedural complications, and clinical outcomes were assessed at discharge. Imaging follow-up was performed with cerebral angiography. Results: One aneurysm coiling procedure failed because of unsuccessful micro-catheterization. Forty-three aneurysms were successfully coil embolized, of which complete occlusion was obtained in 14, subtotal occlusion in 18 and incomplete occlusion in 11. The other 8 aneurysms were treated by sole stent deployment in the parent artery. Procedural complications (2 intraprocedural ruptures and 3 thromboembolic events) occurred in 5 (9.6%) of 52 aneurysms, resulting in permanent morbidity in only 1 (2.2%, 1/46) patient. No rebleeding occurred during clinical follow-up (mean duration, 46.7 months). Of the 16 coiled aneurysms that receiving repetitive angiography, 6 initially completely and 3 subtotally occluded aneurysms remained unchanged, 4 initially subtotally and 3 incompletely occluded aneurysms progressed to total occlusion. Five sole stent deployed aneurysms received angiographic follow-up (mean duration, 10.0 months), of which 3 remained unchanged, 1 became smaller and 1 progressed to total occlusion. Conclusion: Endovascular treatment of tiny intracranial aneurysms is technical feasible and relatively safe. Coil embolisation seems to be effective in preventing early recanalisation, whereas sole stenting technique needs further investigation to determine its effectiveness.

  4. Dynamics of calving glaciers: comparison of three models

    NARCIS (Netherlands)

    Nick, F.M.; Oerlemans, J.

    2006-01-01

    A minimal model of a tidewater glacier based solely on mass conservation is compared with two one-dimensional numerical flowline models, one with the calving rate proportional to water depth, and the other with the flotation criterion as a boundary condition at the glacier terminus. The models were

  5. A new device combining mechanical stimulation of plantar sole and Achilles' tendon to alleviate the consequences of muscle deconditioning.

    Science.gov (United States)

    Canu, Marie-Hélène; Fryziel, Fabrice; Noel, Jean-Pierre; Tiffreau, Vincent; Digumber, Marc; Bastide, Bruno

    2016-05-01

    Limb immobilization or confinement to bed results in a severe atrophy and weakness of lower leg muscles. Full recovery of muscle strength and physical function is rare and may impact the patient's outcome. Studies performed on rodents have demonstrated that the deleterious structural and functional adaptations which occur during muscle deconditioning can be counteracted through adequate physiological stimuli. Thus, based on this fundamental work, we developed a device that combines mechanical stimulation of proprioceptors located in the plantar sole and Achilles' tendon. The device is adapted to patients immobilized and confined to bed. Stimulations can be applied on muscle in passive state. The protocol is non-invasive and is well accepted by patients. This paper presents the technical features of the device, as well as preliminary results of the first clinical study. This device might allow considering new therapeutic strategies for prevention of atrophy in many pathologies.

  6. Skeletal anomalies in reared Senegalese sole Solea senegalensis juveniles: a radiographic approach.

    Science.gov (United States)

    de Azevedo, A M; Losada, A P; Barreiro, A; Barreiro, J D; Ferreiro, I; Riaza, A; Vázquez, S; Quiroga, M I

    2017-04-20

    Reared Senegalese sole Solea senegalensis Kaup show a high incidence of vertebral anomalies; however, little is known about its skeletal anomaly profile in the later farming phases. The purpose of this study was to provide a detailed description and quantification of the most common skeletal anomalies in reared Senegalese sole in the juvenile stage by means of computed radiography. A total of 374 Senegalese sole were classified according to the external morphology of the fish as normal or altered and then radiographed in latero-lateral and in dorso-ventral projections. Radiographic evaluation of anomalies focused especially on vertebral body anomalies (VBA) and vertebral column deviations (VCD). The 2 orthogonal projections provided a more complete visualization of the skeleton. Approximately 75% of the individuals showed at least 1 anomaly, while VBA and/or VCD were detected in 48.9% of the specimens. Regarding external morphology, 88% of the fish were categorized as normal, although about 72% of these normal fish displayed abnormalities in radiographies. The most frequent anomalies consisted of deformations of the caudal complex plates (hypurals, parhypural and epural), preurals and caudal vertebrae. Scoliosis was the most prevalent among VCD, affecting the caudal area in almost 15% of the individuals. The anomaly profile at the juvenile stages showed some differences compared to what has been reported previously in earlier stages of development. In light of these results, further investigation into the progression of skeletal anomalies over time and the causative factors at later stages is required.

  7. Prototype of haptic device for sole of foot using magnetic field sensitive elastomer

    Science.gov (United States)

    Kikuchi, T.; Masuda, Y.; Sugiyama, M.; Mitsumata, T.; Ohori, S.

    2013-02-01

    Walking is one of the most popular activities and a healthy aerobic exercise for the elderly. However, if they have physical and / or cognitive disabilities, sometimes it is challenging to go somewhere they don't know well. The final goal of this study is to develop a virtual reality walking system that allows users to walk in virtual worlds fabricated with computer graphics. We focus on a haptic device that can perform various plantar pressures on users' soles of feet as an additional sense in the virtual reality walking. In this study, we discuss a use of a magnetic field sensitive elastomer (MSE) as a working material for the haptic interface on the sole. The first prototype with MSE was developed and evaluated in this work. According to the measurement of planter pressures, it was found that this device can perform different pressures on the sole of a light-weight user by applying magnetic field on the MSE. The result also implied necessities of the improvement of the magnetic circuit and the basic structure of the mechanism of the device.

  8. Histopathology, enzyme activities, and PAH metabolites in English sole collected near coastal pulp mills

    Energy Technology Data Exchange (ETDEWEB)

    Brand, D.G. [Univ. of Victoria, British Columbia (Canada)

    1995-12-31

    The bottom-feeding flatfish, English sole (Pleuronectes vetulus), is widely distributed along the B.C. Pacific coast and fulfills a majority of the requirements as a sentinel species for environmental effects monitoring programs. Studies involving the use of histopathological, biochemical, and chemical tools with English sole collected near the vicinity of B.C. pulp mills are currently being conducted. Analysis, to date, has revealed idiopathic liver lesions to be strongly dependent on location of capture with a prevalence of 30% preneoplastic and neoplastic lesions found in fish collected near pulp mills. All fish residing near pulp mills show hepatocellular hemosiderosis, an iron storage disorder. The mixed-function oxidizing enzyme, EROD, was found to be induced in fish collected near pulp mills. However, the levels of conjugating enzymes, GST and UDP-GT, were found to be unchanged when compared with reference fish. PAH metabolites, measured as FACs in bile, are also present in English sole collected from the mill sites and the conjugated derivatives are presently being identified by HPLC/ES-MS techniques, The relationships between these observations will be discussed.

  9. Computer vision for shoe upper profile measurement via upper and sole conformal matching

    Science.gov (United States)

    Hu, Zhongxu; Bicker, Robert; Taylor, Paul; Marshall, Chris

    2007-01-01

    This paper describes a structured light computer vision system applied to the measurement of the 3D profile of shoe uppers. The trajectory obtained is used to guide an industrial robot for automatic edge roughing around the contour of the shoe upper so that the bonding strength can be improved. Due to the specific contour and unevenness of the shoe upper, even if the 3D profile is obtained using computer vision, it is still difficult to reliably define the roughing path around the shape. However, the shape of the corresponding shoe sole is better defined, and it is much easier to measure the edge using computer vision. Therefore, a feasible strategy is to measure both the upper and sole profiles, and then align and fit the sole contour to the upper, in order to obtain the best fit. The trajectory of the edge of the desired roughing path is calculated and is then smoothed and interpolated using NURBS curves to guide an industrial robot for shoe upper surface removal; experiments show robust and consistent results. An outline description of the structured light vision system is given here, along with the calibration techniques used.

  10. Field based model for pedestrian dynamics

    Science.gov (United States)

    Yu, Bin; Zhang, Michael; Wang, Zhongren

    2018-03-01

    A pedestrian’s physical movement is simulated as a response to the pedestrian subjective evaluation of the objective environment. The objective environment is modeled by presumed fields statically or dynamically superposed. Regulation functions, which consider not only force caused by presumed fields but also local crowd densities around pedestrians, are introduced for consideration of pedestrians’ intelligence. Numerical experiments indicate that the model can be calibrated to reproduce a fundamental diagram that matches an empirical one proposed by Weidmann. Such experiments prove the model to be a useful tool for study of pedestrian dynamics.

  11. Chimeric human parainfluenza virus bearing the Ebola virus glycoprotein as the sole surface protein is immunogenic and highly protective against Ebola virus challenge

    International Nuclear Information System (INIS)

    Bukreyev, Alexander; Marzi, Andrea; Feldmann, Friederike; Zhang Liqun; Yang Lijuan; Ward, Jerrold M.; Dorward, David W.; Pickles, Raymond J.; Murphy, Brian R.; Feldmann, Heinz; Collins, Peter L.

    2009-01-01

    We generated a new live-attenuated vaccine against Ebola virus (EBOV) based on a chimeric virus HPIV3/ΔF-HN/EboGP that contains the EBOV glycoprotein (GP) as the sole transmembrane envelope protein combined with the internal proteins of human parainfluenza virus type 3 (HPIV3). Electron microscopy analysis of the virus particles showed that they have an envelope and surface spikes resembling those of EBOV and a particle size and shape resembling those of HPIV3. When HPIV3/ΔF-HN/EboGP was inoculated via apical surface of an in vitro model of human ciliated airway epithelium, the virus was released from the apical surface; when applied to basolateral surface, the virus infected basolateral cells but did not spread through the tissue. Following intranasal (IN) inoculation of guinea pigs, scattered infected cells were detected in the lungs by immunohistochemistry, but infectious HPIV3/ΔF-HN/EboGP could not be recovered from the lungs, blood, or other tissues. Despite the attenuation, the virus was highly immunogenic, and a single IN dose completely protected the animals against a highly lethal intraperitoneal challenge of guinea pig-adapted EBOV

  12. Demand forecast model based on CRM

    Science.gov (United States)

    Cai, Yuancui; Chen, Lichao

    2006-11-01

    With interiorizing day by day management thought that regarding customer as the centre, forecasting customer demand becomes more and more important. In the demand forecast of customer relationship management, the traditional forecast methods have very great limitation because much uncertainty of the demand, these all require new modeling to meet the demands of development. In this paper, the notion is that forecasting the demand according to characteristics of the potential customer, then modeling by it. The model first depicts customer adopting uniform multiple indexes. Secondly, the model acquires characteristic customers on the basis of data warehouse and the technology of data mining. The last, there get the most similar characteristic customer by their comparing and forecast the demands of new customer by the most similar characteristic customer.

  13. An operator model-based filtering scheme

    International Nuclear Information System (INIS)

    Sawhney, R.S.; Dodds, H.L.; Schryer, J.C.

    1990-01-01

    This paper presents a diagnostic model developed at Oak Ridge National Laboratory (ORNL) for off-normal nuclear power plant events. The diagnostic model is intended to serve as an embedded module of a cognitive model of the human operator, one application of which could be to assist control room operators in correctly responding to off-normal events by providing a rapid and accurate assessment of alarm patterns and parameter trends. The sequential filter model is comprised of two distinct subsystems --- an alarm analysis followed by an analysis of interpreted plant signals. During the alarm analysis phase, the alarm pattern is evaluated to generate hypotheses of possible initiating events in order of likelihood of occurrence. Each hypothesis is further evaluated through analysis of the current trends of state variables in order to validate/reject (in the form of increased/decreased certainty factor) the given hypothesis. 7 refs., 4 figs

  14. Models for Patch-Based Image Restoration

    Directory of Open Access Journals (Sweden)

    Mithun Das Gupta

    2009-01-01

    Full Text Available We present a supervised learning approach for object-category specific restoration, recognition, and segmentation of images which are blurred using an unknown kernel. The novelty of this work is a multilayer graphical model which unifies the low-level vision task of restoration and the high-level vision task of recognition in a cooperative framework. The graphical model is an interconnected two-layer Markov random field. The restoration layer accounts for the compatibility between sharp and blurred images and models the association between adjacent patches in the sharp image. The recognition layer encodes the entity class and its location in the underlying scene. The potentials are represented using nonparametric kernel densities and are learnt from training data. Inference is performed using nonparametric belief propagation. Experiments demonstrate the effectiveness of our model for the restoration and recognition of blurred license plates as well as face images.

  15. Models for Patch-Based Image Restoration

    Directory of Open Access Journals (Sweden)

    Petrovic Nemanja

    2009-01-01

    Full Text Available Abstract We present a supervised learning approach for object-category specific restoration, recognition, and segmentation of images which are blurred using an unknown kernel. The novelty of this work is a multilayer graphical model which unifies the low-level vision task of restoration and the high-level vision task of recognition in a cooperative framework. The graphical model is an interconnected two-layer Markov random field. The restoration layer accounts for the compatibility between sharp and blurred images and models the association between adjacent patches in the sharp image. The recognition layer encodes the entity class and its location in the underlying scene. The potentials are represented using nonparametric kernel densities and are learnt from training data. Inference is performed using nonparametric belief propagation. Experiments demonstrate the effectiveness of our model for the restoration and recognition of blurred license plates as well as face images.

  16. Tokamak transport based on the Braginskii model

    International Nuclear Information System (INIS)

    Weitzner, H.

    1987-01-01

    The two-fluid model of Braginskii is applied to the case of a moderately large tokamak. By estimation of the order of magnitude of the various effects and omission of small terms a somewhat simpler reduced two-fluid Braginskii model is obtained. The model applies on a time scale of order τ e m i /m e , where τ e is the electron-electron collision time, and energy confinement time is of this order. With electron and ion flow velocities no larger than is necessary to obtain the correct equilibrium currents, classical parallel viscosity becomes a dominant dissipative mechanism. The model allows for the slow evolution of equilibrium states. The equilibria, which include static, ideal magnetohydrodynamic equilibria as a special case, are described. Generally the number density, electrostatic potential, and flows are not constant on a flux surface. The procedure for determination of the slow evolution of the equilibrium is sketched. (orig.)

  17. Base Flow Model Validation, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — The innovation is the systematic "building-block" validation of CFD/turbulence models employing a GUI driven CFD code (RPFM) and existing as well as new data sets to...

  18. Inferring fish escape behaviour in trawls based on catch comparison data: Model development and evaluation based on data from Skagerrak, Denmark

    DEFF Research Database (Denmark)

    Krag, Ludvig Ahm; Herrmann, Bent; Karlsen, Junita Diana

    2014-01-01

    ), haddock Melanogrammus aeglefinus), saithe (Pollachius virens), witch flounder (Glyptocephalus cynoglossus), and lemon sole (Microstomus kitt) and quantified the extent to which behavioural responses set limits for the large mesh panel’s selective efficiency. Around 85% of saithe, 80% of haddock, 44......% of witch flounder, 55% of lemon sole, and 55% of cod (below 68 cm) contacted the large mesh panel and escaped. We also demonstrated the need to account for potential selectivity in the trawl body, as it can bias the assessment of length-based escape behaviour. Our indirect assessment of fish behaviour...

  19. A methodology to support multidisciplinary model-based water management

    NARCIS (Netherlands)

    Scholten, H.; Kassahun, A.; Refsgaard, J.C.; Kargas, Th.; Gavardinas, C.; Beulens, A.J.M.

    2007-01-01

    Quality assurance in model based water management is needed because of some frequently perceived shortcomings, e.g. a lack of mutual understanding between modelling team members, malpractice and a tendency of modellers to oversell model capabilities. Initiatives to support quality assurance focus on

  20. Refinement-Based Student Modeling and Automated Bug Library Construction.

    Science.gov (United States)

    Baffes, Paul; Mooney, Raymond

    1996-01-01

    Discussion of student modeling and intelligent tutoring systems focuses on the development of the ASSERT algorithm (Acquiring Stereotypical Student Errors by Refining Theories). Topics include overlay modeling; bug libraries (databases of student misconceptions); dynamic modeling; refinement-based modeling; and experimental results from tests at…

  1. A general model for membrane-based separation processes

    DEFF Research Database (Denmark)

    Soni, Vipasha; Abildskov, Jens; Jonsson, Gunnar Eigil

    2009-01-01

    behaviour will play an important role. In this paper, modelling of membrane-based processes for separation of gas and liquid mixtures are considered. Two general models, one for membrane-based liquid separation processes (with phase change) and another for membrane-based gas separation are presented....... The separation processes covered are: membrane-based gas separation processes, pervaporation and various types of membrane distillation processes. The specific model for each type of membrane-based process is generated from the two general models by applying the specific system descriptions and the corresponding......A separation process could be defined as a process that transforms a given mixture of chemicals into two or more compositionally distinct end-use products. One way to design these separation processes is to employ a model-based approach, where mathematical models that reliably predict the process...

  2. LINKAGES: An Individual-based Forest Ecosystem Biogeochemistry Model

    Data.gov (United States)

    National Aeronautics and Space Administration — ABSTRACT: This model product contains the source codes for version 1 of the individual-based forest ecosystem biogeochemistry model LINKAGES and two subsequent...

  3. Prediction of speech intelligibility based on an auditory preprocessing model

    DEFF Research Database (Denmark)

    Christiansen, Claus Forup Corlin; Pedersen, Michael Syskind; Dau, Torsten

    2010-01-01

    Classical speech intelligibility models, such as the speech transmission index (STI) and the speech intelligibility index (SII) are based on calculations on the physical acoustic signals. The present study predicts speech intelligibility by combining a psychoacoustically validated model of auditory...

  4. LINKAGES: An Individual-based Forest Ecosystem Biogeochemistry Model

    Data.gov (United States)

    National Aeronautics and Space Administration — This model product contains the source codes for version 1 of the individual-based forest ecosystem biogeochemistry model LINKAGES and two subsequent versions as...

  5. Tokamak reactor cost model based on STARFIRE/WILDCAT costing

    International Nuclear Information System (INIS)

    Evans, K. Jr.

    1983-03-01

    A cost model is presented which is useful for survey and comparative studies of tokamak reactors. The model is heavily based on STARFIRE and WILDCAT costing guidelines, philosophies, and procedures and reproduces the costing for these devices quite accurately

  6. Model-Based Assurance Case+ (MBAC+): Tutorial on Modeling Radiation Hardness Assurance Activities

    Science.gov (United States)

    Austin, Rebekah; Label, Ken A.; Sampson, Mike J.; Evans, John; Witulski, Art; Sierawski, Brian; Karsai, Gabor; Mahadevan, Nag; Schrimpf, Ron; Reed, Robert A.

    2017-01-01

    This presentation will cover why modeling is useful for radiation hardness assurance cases, and also provide information on Model-Based Assurance Case+ (MBAC+), NASAs Reliability Maintainability Template, and Fault Propagation Modeling.

  7. Preservation Obscures Pelagic Deep-Sea Fish Diversity: Doubling the Number of Sole-Bearing Opisthoproctids and Resurrection of the Genus Monacoa (Opisthoproctidae, Argentiniformes)

    Science.gov (United States)

    Sado, Tetsuya; Hahn, Christoph; Byrkjedal, Ingvar; Miya, Masaki

    2016-01-01

    The family Opisthoproctidae (barreleyes) constitutes one of the most peculiar looking and unknown deep-sea fish groups in terms of taxonomy and specialized adaptations. All the species in the family are united by the possession of tubular eyes, with one distinct lineage exhibiting also drastic shortening of the body. Two new species of the mesopelagic opisthoproctid mirrorbelly genus Monacoa are described based on pigmentation patterns of the “sole”—a unique vertebrate structure used in the reflection and control of bioluminescence in most short-bodied forms. Different pigmentation patterns of the soles, previously noted as intraspecific variations based on preserved specimens, are here shown species-specific and likely used for communication in addition to counter-illumination of down-welling sunlight. The genus Monacoa is resurrected from Opisthoproctus based on extensive morphological synaphomorphies pertaining to the anal fin and snout. Doubling the species diversity within sole-bearing opisthoproctids, including recognition of two genera, is unambiguously supported by mitogenomic DNA sequence data. Regular fixation with formalin and alcohol preservation is shown problematic concerning the retention of species-specific pigmentation patterns. Examination or photos of fresh material before formalin fixation is shown paramount for correct species recognition of sole-bearing opisthoproctids—a relatively unknown issue concerning species diversity in the deep-sea pelagic realm. PMID:27508419

  8. Qualitative model-based diagnosis using possibility theory

    Science.gov (United States)

    Joslyn, Cliff

    1994-01-01

    The potential for the use of possibility in the qualitative model-based diagnosis of spacecraft systems is described. The first sections of the paper briefly introduce the Model-Based Diagnostic (MBD) approach to spacecraft fault diagnosis; Qualitative Modeling (QM) methodologies; and the concepts of possibilistic modeling in the context of Generalized Information Theory (GIT). Then the necessary conditions for the applicability of possibilistic methods to qualitative MBD, and a number of potential directions for such an application, are described.

  9. The fractional volatility model: An agent-based interpretation

    Science.gov (United States)

    Vilela Mendes, R.

    2008-06-01

    Based on the criteria of mathematical simplicity and consistency with empirical market data, a model with volatility driven by fractional noise has been constructed which provides a fairly accurate mathematical parametrization of the data. Here, some features of the model are reviewed and extended to account for leverage effects. Using agent-based models, one tries to find which agent strategies and (or) properties of the financial institutions might be responsible for the features of the fractional volatility model.

  10. Probabilistic reasoning for assembly-based 3D modeling

    KAUST Repository

    Chaudhuri, Siddhartha

    2011-01-01

    Assembly-based modeling is a promising approach to broadening the accessibility of 3D modeling. In assembly-based modeling, new models are assembled from shape components extracted from a database. A key challenge in assembly-based modeling is the identification of relevant components to be presented to the user. In this paper, we introduce a probabilistic reasoning approach to this problem. Given a repository of shapes, our approach learns a probabilistic graphical model that encodes semantic and geometric relationships among shape components. The probabilistic model is used to present components that are semantically and stylistically compatible with the 3D model that is being assembled. Our experiments indicate that the probabilistic model increases the relevance of presented components. © 2011 ACM.

  11. Model-Based Reasoning in Humans Becomes Automatic with Training.

    Directory of Open Access Journals (Sweden)

    Marcos Economides

    2015-09-01

    Full Text Available Model-based and model-free reinforcement learning (RL have been suggested as algorithmic realizations of goal-directed and habitual action strategies. Model-based RL is more flexible than model-free but requires sophisticated calculations using a learnt model of the world. This has led model-based RL to be identified with slow, deliberative processing, and model-free RL with fast, automatic processing. In support of this distinction, it has recently been shown that model-based reasoning is impaired by placing subjects under cognitive load--a hallmark of non-automaticity. Here, using the same task, we show that cognitive load does not impair model-based reasoning if subjects receive prior training on the task. This finding is replicated across two studies and a variety of analysis methods. Thus, task familiarity permits use of model-based reasoning in parallel with other cognitive demands. The ability to deploy model-based reasoning in an automatic, parallelizable fashion has widespread theoretical implications, particularly for the learning and execution of complex behaviors. It also suggests a range of important failure modes in psychiatric disorders.

  12. Model-Based Reasoning in Humans Becomes Automatic with Training

    Science.gov (United States)

    Lübbert, Annika; Guitart-Masip, Marc; Dolan, Raymond J.

    2015-01-01

    Model-based and model-free reinforcement learning (RL) have been suggested as algorithmic realizations of goal-directed and habitual action strategies. Model-based RL is more flexible than model-free but requires sophisticated calculations using a learnt model of the world. This has led model-based RL to be identified with slow, deliberative processing, and model-free RL with fast, automatic processing. In support of this distinction, it has recently been shown that model-based reasoning is impaired by placing subjects under cognitive load—a hallmark of non-automaticity. Here, using the same task, we show that cognitive load does not impair model-based reasoning if subjects receive prior training on the task. This finding is replicated across two studies and a variety of analysis methods. Thus, task familiarity permits use of model-based reasoning in parallel with other cognitive demands. The ability to deploy model-based reasoning in an automatic, parallelizable fashion has widespread theoretical implications, particularly for the learning and execution of complex behaviors. It also suggests a range of important failure modes in psychiatric disorders. PMID:26379239

  13. Physics-Based Pneumatic Hammer Instability Model, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — Florida Turbine Technologies (FTT) proposes to conduct research necessary to develop a physics-based pneumatic hammer instability model for hydrostatic bearings...

  14. Students Social Based Mobility Model for MANET-DTN Networks

    OpenAIRE

    Dávid Hrabčák; Martin Matis; L’ubomír Doboš; Ján Papaj

    2017-01-01

    In the real world, wireless mobile devices are carried by humans. For this reason, it is useful if mobility models as simulation tools used to test routing protocols and other MANET-DTN features follow the behaviour of humans. In this paper, we propose a new social based mobility model called Students Social Based Mobility Model (SSBMM). This mobility model is inspired by the daily routine of student’s life. Since many current social based mobility models give nodes freedom in terms of moveme...

  15. Airfoil Shape Optimization based on Surrogate Model

    Science.gov (United States)

    Mukesh, R.; Lingadurai, K.; Selvakumar, U.

    2018-02-01

    Engineering design problems always require enormous amount of real-time experiments and computational simulations in order to assess and ensure the design objectives of the problems subject to various constraints. In most of the cases, the computational resources and time required per simulation are large. In certain cases like sensitivity analysis, design optimisation etc where thousands and millions of simulations have to be carried out, it leads to have a life time of difficulty for designers. Nowadays approximation models, otherwise called as surrogate models (SM), are more widely employed in order to reduce the requirement of computational resources and time in analysing various engineering systems. Various approaches such as Kriging, neural networks, polynomials, Gaussian processes etc are used to construct the approximation models. The primary intention of this work is to employ the k-fold cross validation approach to study and evaluate the influence of various theoretical variogram models on the accuracy of the surrogate model construction. Ordinary Kriging and design of experiments (DOE) approaches are used to construct the SMs by approximating panel and viscous solution algorithms which are primarily used to solve the flow around airfoils and aircraft wings. The method of coupling the SMs with a suitable optimisation scheme to carryout an aerodynamic design optimisation process for airfoil shapes is also discussed.

  16. Model-based Prognostics under Limited Sensing

    Data.gov (United States)

    National Aeronautics and Space Administration — Prognostics is crucial to providing reliable condition-based maintenance decisions. To obtain accurate predictions of component life, a variety of sensors are often...

  17. Optimal portfolio model based on WVAR

    OpenAIRE

    Hao, Tianyu

    2012-01-01

    This article is focused on using a new measurement of risk-- Weighted Value at Risk to develop a new method of constructing initiate from the TVAR solving problem, based on MATLAB software, using the historical simulation method (avoiding income distribution will be assumed to be normal), the results of previous studies also based on, study the U.S. Nasdaq composite index, combining the Simpson formula for the solution of TVAR and its deeply study; then, through the representation of WVAR for...

  18. Geometric deviation modeling by kinematic matrix based on Lagrangian coordinate

    Science.gov (United States)

    Liu, Weidong; Hu, Yueming; Liu, Yu; Dai, Wanyi

    2015-09-01

    Typical representation of dimension and geometric accuracy is limited to the self-representation of dimension and geometric deviation based on geometry variation thinking, yet the interactivity affection of geometric variation and gesture variation of multi-rigid body is not included. In this paper, a kinematic matrix model based on Lagrangian coordinate is introduced, with the purpose of unified model for geometric variation and gesture variation and their interactive and integrated analysis. Kinematic model with joint, local base and movable base is built. The ideal feature of functional geometry is treated as the base body; the fitting feature of functional geometry is treated as the adjacent movable body; the local base of the kinematic model is fixed onto the ideal geometry, and the movable base of the kinematic model is fixed onto the fitting geometry. Furthermore, the geometric deviation is treated as relative location or rotation variation between the movable base and the local base, and it's expressed by the Lagrangian coordinate. Moreover, kinematic matrix based on Lagrangian coordinate for different types of geometry tolerance zones is constructed, and total freedom for each kinematic model is discussed. Finally, the Lagrangian coordinate library, kinematic matrix library for geometric deviation modeling is illustrated, and an example of block and piston fits is introduced. Dimension and geometric tolerances of the shaft and hole fitting feature are constructed by kinematic matrix and Lagrangian coordinate, and the results indicate that the proposed kinematic matrix is capable and robust in dimension and geometric tolerances modeling.

  19. Numerical Based Linear Model for Dipole Magnets

    Energy Technology Data Exchange (ETDEWEB)

    Li,Y.; Krinsky, S.; Rehak, M.

    2009-05-04

    In this paper, we discuss an algorithm for constructing a numerical linear optics model for dipole magnets from a 3D field map. The difference between the numerical model and K. Brown's analytic approach is investigated and clarified. It was found that the optics distortion due to the dipoles' fringe focusing must be properly taken into account to accurately determine the chromaticities. In NSLS-II, there are normal dipoles with 35-mm gap and dipoles for infrared sources with 90-mm gap. This linear model of the dipole magnets is applied to the NSLS-II lattice design to match optics parameters between the DBA cells having dipoles with different gaps.

  20. Modeling cookoff of HMX based PBX explosives

    Energy Technology Data Exchange (ETDEWEB)

    Hobbs, Michael L.

    2017-03-01

    We have previously developed a PBX 9501 cookoff model for the plastic bonded explosive PBX 9501 consisting of 95 wt% octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazoncine (HMX), 2.5 wt% Estane® 5703 (a polyurethane thermoplastic), and 2.5 wt% of a nitroplasticizer (NP): BDNPA/F, a 50/50 wt% eutectic mixture bis(2,2-dinitropropyl)-acetal (BDNPA) and bis(2,2-dinitropropyl)-formal (BDNPF). This fivestep model includes desorption of water, decomposition of the NP to form NO2, reaction of the NO2 with Estane and HMX, and decomposition of HMX [1]. This model has been successfully validated with data from six laboratories with scales ranging from 2 g to more than 2.5 kg of explosive. We have determined, that the PBX 9501 model can be used to predict cookoff of other plastic bonded explosives containing HMX and an inert binder, such as LX-04 consisting of 85 wt% HMX and 15 wt% Viton A (vinylidine fluoride/hexafluoropropylene copolymer), LX-07 (90 wt% HMX and 10 wt% Viton A), LX- 10-0 (95 wt% HMX and 5 wt% Viton A), and LX-14 consisting of 95.5 wt % HMX and 4.5 wt% Estane® 5702-F1 (a polyurethane thermoplastic). Normally our cookoff models are verified using Sandia’s Instrumented Thermal Initiation (SITI) experiment. However, SITI data for LX-04, LX-07, LX-10-0, and LX-14 are not available at pressed density; although, some molding powder SITI data on LX-10-0 and LX-14 exists. Tarver and Tran [2] provide some one-dimensional time-to-explosion (ODTX) data for these explosives. The applicability of the PBX 9501 model to LX-04, LX-07, LX-10-0, AND LX-14 was made using this ODTX data [2]. The PBX 9501 model is applied to these other explosives by accounting for the correct amount of HMX in the explosive and limiting the NP reaction. We have found the PBX 9501 model to be useful for predicting the response of these PBXs to abnormal thermal environments such as fire.

  1. Probabilistic mixture-based image modelling

    Czech Academy of Sciences Publication Activity Database

    Haindl, Michal; Havlíček, Vojtěch; Grim, Jiří

    2011-01-01

    Roč. 47, č. 3 (2011), s. 482-500 ISSN 0023-5954 R&D Projects: GA MŠk 1M0572; GA ČR GA102/08/0593 Grant - others:CESNET(CZ) 387/2010; GA MŠk(CZ) 2C06019; GA ČR(CZ) GA103/11/0335 Institutional research plan: CEZ:AV0Z10750506 Keywords : BTF texture modelling * discrete distribution mixtures * Bernoulli mixture * Gaussian mixture * multi-spectral texture modelling Subject RIV: BD - Theory of Information Impact factor: 0.454, year: 2011 http://library.utia.cas.cz/separaty/2011/RO/haindl-0360244.pdf

  2. Model based monitoring of stormwater runoff quality

    DEFF Research Database (Denmark)

    Birch, Heidi; Vezzaro, Luca; Mikkelsen, Peter Steen

    2012-01-01

    Monitoring of micropollutants (MP) in stormwater is essential to evaluate the impacts of stormwater on the receiving aquatic environment. The aim of this study was to investigate how different strategies for monitoring of stormwater quality (combination of model with field sampling) affect...... the information obtained about MPs discharged from the monitored system. A dynamic stormwater quality model was calibrated using MP data collected by volume-proportional and passive sampling in a storm drainage system in the outskirts of Copenhagen (Denmark) and a 10-year rain series was used to find annual...

  3. Understanding uncertainty in process-based hydrological models

    Science.gov (United States)

    Clark, M. P.; Kavetski, D.; Slater, A. G.; Newman, A. J.; Marks, D. G.; Landry, C.; Lundquist, J. D.; Rupp, D. E.; Nijssen, B.

    2013-12-01

    Building an environmental model requires making a series of decisions regarding the appropriate representation of natural processes. While some of these decisions can already be based on well-established physical understanding, gaps in our current understanding of environmental dynamics, combined with incomplete knowledge of properties and boundary conditions of most environmental systems, make many important modeling decisions far more ambiguous. There is consequently little agreement regarding what a 'correct' model structure is, especially at relatively larger spatial scales such as catchments and beyond. In current practice, faced with such a range of decisions, different modelers will generally make different modeling decisions, often on an ad hoc basis, based on their balancing of process understanding, the data available to evaluate the model, the purpose of the modeling exercise, and their familiarity with or investment in an existing model infrastructure. This presentation describes development and application of multiple-hypothesis models to evaluate process-based hydrologic models. Our numerical model uses robust solutions of the hydrology and thermodynamic governing equations as the structural core, and incorporates multiple options to represent the impact of different modeling decisions, including multiple options for model parameterizations (e.g., below-canopy wind speed, thermal conductivity, storage and transmission of liquid water through soil, etc.), as well as multiple options for model architecture, that is, the coupling and organization of different model components (e.g., representations of sub-grid variability and hydrologic connectivity, coupling with groundwater, etc.). Application of this modeling framework across a collection of different research basins demonstrates that differences among model parameterizations are often overwhelmed by differences among equally-plausible model parameter sets, while differences in model architecture lead

  4. From qualitative reasoning models to Bayesian-based learner modeling

    NARCIS (Netherlands)

    Milošević, U.; Bredeweg, B.; de Kleer, J.; Forbus, K.D.

    2010-01-01

    Assessing the knowledge of a student is a fundamental part of intelligent learning environments. We present a Bayesian network based approach to dealing with uncertainty when estimating a learner’s state of knowledge in the context of Qualitative Reasoning (QR). A proposal for a global architecture

  5. CEAI: CCM based Email Authorship Identification Model

    DEFF Research Database (Denmark)

    Nizamani, Sarwat; Memon, Nasrullah

    2013-01-01

    authors, 89% for 25 authors, and 81% for 50 authors, respectively on Enron data set, while 89.5% accuracy has been achieved on authors' constructed real email data set. The results on Enron data set have been achieved on quite a large number of authors as compared to the models proposed by Iqbal et al. [1...

  6. A Qualitative Acceleration Model Based on Intervals

    Directory of Open Access Journals (Sweden)

    Ester MARTINEZ-MARTIN

    2013-08-01

    Full Text Available On the way to autonomous service robots, spatial reasoning plays a main role since it properly deals with problems involving uncertainty. In particular, we are interested in knowing people's pose to avoid collisions. With that aim, in this paper, we present a qualitative acceleration model for robotic applications including representation, reasoning and a practical application.

  7. Port-Based Modeling in Different Domains

    NARCIS (Netherlands)

    Batlle, C.; Couenne, F.; Doria-Cerezo, A.; Fossas, E.; Jallut, C.; Lefevre, L.; Le Gorrec, Y.; Maschke, B.M.; Ortega, R.; Schlacher, K.; Tayakout, M.; Duindam, V.; Macchelli, Alessandro; Stramigioli, Stefano; Bruyninckx, Herman

    2009-01-01

    In this Chapter we present some detailed examples of modelling in several domains using port and port-Hamiltonian concepts, as have been presented in the previous chapters. We start with the electromechanical domain in Sect. 3.1, while in Sect. 3.2 it is shown how port-Hamiltonian systems can be

  8. Sparse-Based Modeling of Hyperspectral Data

    DEFF Research Database (Denmark)

    Calvini, Rosalba; Ulrici, Alessandro; Amigo Rubio, Jose Manuel

    2016-01-01

    One of the main issues of hyperspectral imaging data is to unravel the relevant, yet overlapped, huge amount of information contained in the spatial and spectral dimensions. When dealing with the application of multivariate models in such high-dimensional data, sparsity can improve...

  9. Model-based satellite image fusion

    DEFF Research Database (Denmark)

    Aanæs, Henrik; Sveinsson, J. R.; Nielsen, Allan Aasbjerg

    2008-01-01

    A method is proposed for pixel-level satellite image fusion derived directly from a model of the imaging sensor. By design, the proposed method is spectrally consistent. It is argued that the proposed method needs regularization, as is the case for any method for this problem. A framework for pixel...

  10. Automata-Based CSL Model Checking

    DEFF Research Database (Denmark)

    Zhang, Lijun; Jansen, David N.; Nielson, Flemming

    2011-01-01

    For continuous-time Markov chains, the model-checking problem with respect to continuous-time stochastic logic (CSL) has been introduced and shown to be decidable by Aziz, Sanwal, Singhal and Brayton in 1996. The presented decision procedure, however, has exponential complexity. In this paper, we...

  11. Model based process-product design and analysis

    DEFF Research Database (Denmark)

    Gani, Rafiqul

    This paper gives a perspective on modelling and the important role it has within product-process design and analysis. Different modelling issues related to development and application of systematic model-based solution approaches for product-process design is discussed and the need for a hybrid......, forms and complexity, together with their associated parameters. An example of a model-based system for design of chemicals based formulated products is also given....... model-based framework is highlighted. This framework should be able to manage knowledge-data, models, and associated methods and tools integrated with design work-flows and data-flows for specific product-process design problems. In particular, the framework needs to manage models of different types...

  12. A Correlation-Based Transition Model using Local Variables. Part 1; Model Formation

    Science.gov (United States)

    Menter, F. R.; Langtry, R. B.; Likki, S. R.; Suzen, Y. B.; Huang, P. G.; Volker, S.

    2006-01-01

    A new correlation-based transition model has been developed, which is based strictly on local variables. As a result, the transition model is compatible with modern computational fluid dynamics (CFD) approaches, such as unstructured grids and massive parallel execution. The model is based on two transport equations, one for intermittency and one for the transition onset criteria in terms of momentum thickness Reynolds number. The proposed transport equations do not attempt to model the physics of the transition process (unlike, e.g., turbulence models) but from a framework for the implementation of correlation-based models into general-purpose CFD methods.

  13. Compartment-based hydrodynamics and water quality modeling of a northern Everglades wetland, Florida, USA

    Science.gov (United States)

    Wang, Hongqing; Meselhe, Ehab A.; Waldon, Michael G.; Harwell, Matthew C.; Chen, Chunfang

    2012-01-01

    The last remaining large remnant of softwater wetlands in the US Florida Everglades lies within the Arthur R. Marshall Loxahatchee National Wildlife Refuge. However, Refuge water quality today is impacted by pumped stormwater inflows to the eutrophic and mineral-enriched 100-km canal, which circumscribes the wetland. Optimal management is a challenge and requires scientifically based predictive tools to assess and forecast the impacts of water management on Refuge water quality. In this research, we developed a compartment-based numerical model of hydrodynamics and water quality for the Refuge. Using the numerical model, we examined the dynamics in stage, water depth, discharge from hydraulic structures along the canal, and exchange flow among canal and marsh compartments. We also investigated the transport of chloride, sulfate and total phosphorus from the canal to the marsh interior driven by hydraulic gradients as well as biological removal of sulfate and total phosphorus. The model was calibrated and validated using long-term stage and water quality data (1995-2007). Statistical analysis indicates that the model is capable of capturing the spatial (from canal to interior marsh) gradients of constituents across the Refuge. Simulations demonstrate that flow from the eutrophic and mineral-enriched canal impacts chloride and sulfate in the interior marsh. In contrast, total phosphorus in the interior marsh shows low sensitivity to intrusion and dispersive transport. We conducted a rainfall-driven scenario test in which the pumped inflow concentrations of chloride, sulfate and total phosphorus were equal to rainfall concentrations (wet deposition). This test shows that pumped inflow is the dominant factor responsible for the substantially increased chloride and sulfate concentrations in the interior marsh. Therefore, the present day Refuge should not be classified as solely a rainfall-driven or ombrotrophic wetland. The model provides an effective screening tool for

  14. An Emotional Agent Model Based on Granular Computing

    Directory of Open Access Journals (Sweden)

    Jun Hu

    2012-01-01

    Full Text Available Affective computing has a very important significance for fulfilling intelligent information processing and harmonious communication between human being and computers. A new model for emotional agent is proposed in this paper to make agent have the ability of handling emotions, based on the granular computing theory and the traditional BDI agent model. Firstly, a new emotion knowledge base based on granular computing for emotion expression is presented in the model. Secondly, a new emotional reasoning algorithm based on granular computing is proposed. Thirdly, a new emotional agent model based on granular computing is presented. Finally, based on the model, an emotional agent for patient assistant in hospital is realized, experiment results show that it is efficient to handle simple emotions.

  15. Mechanics and model-based control of advanced engineering systems

    CERN Document Server

    Irschik, Hans; Krommer, Michael

    2014-01-01

    Mechanics and Model-Based Control of Advanced Engineering Systems collects 32 contributions presented at the International Workshop on Advanced Dynamics and Model Based Control of Structures and Machines, which took place in St. Petersburg, Russia in July 2012. The workshop continued a series of international workshops, which started with a Japan-Austria Joint Workshop on Mechanics and Model Based Control of Smart Materials and Structures and a Russia-Austria Joint Workshop on Advanced Dynamics and Model Based Control of Structures and Machines. In the present volume, 10 full-length papers based on presentations from Russia, 9 from Austria, 8 from Japan, 3 from Italy, one from Germany and one from Taiwan are included, which represent the state of the art in the field of mechanics and model based control, with particular emphasis on the application of advanced structures and machines.

  16. Flow Formulation-based Model for the Curriculum-based Course Timetabling Problem

    DEFF Research Database (Denmark)

    Bagger, Niels-Christian Fink; Kristiansen, Simon; Sørensen, Matias

    2015-01-01

    In this work we will present a new mixed integer programming formulation for the curriculum-based course timetabling problem. We show that the model contains an underlying network model by dividing the problem into two models and then connecting the two models back into one model using a maximum ow...

  17. A model-based control system concept

    International Nuclear Information System (INIS)

    Aarzen, K.E.

    1992-12-01

    This paper presents an overview of a new concept for DCSs developed within the KBRTCS (Knowledge-Based Real-Time Control Systems) project performed between 1988 and 1991 as a part of the Swedish IT4 programme. The partners of the project have been the Department of Automatic Control at Lund University, Asea Brown Boveri, and during parts of the project, SattControl, and TeleLogic. The aim of the project has been to develop a concept for future generations of DCSs based on a plant database containing a description of the plant together with the control system. The database is object-based and supports multiple views of an objects. A demonstrator is presented where a DCS system of this type is emulated. The demonstrator contains a number of control, monitoring, and diagnosis applications that execute in real time against a simulations of Steritherm sterilization process. (25 refs.)

  18. Biodegradation and utilization of 4-n-nonylphenol by Aspergillus versicolor as a sole carbon and energy source

    Energy Technology Data Exchange (ETDEWEB)

    Krupiński, Mariusz; Janicki, Tomasz [Department of Industrial Microbiology and Biotechnology, University of Lodz, Banacha 12/16, 90-237 Łódź (Poland); Pałecz, Bartłomiej [Department of Physical Chemistry, University of Lodz, Pomorska 165, 90-236 Łódź (Poland); Długoński, Jerzy, E-mail: jdlugo@biol.uni.lodz.pl [Department of Industrial Microbiology and Biotechnology, University of Lodz, Banacha 12/16, 90-237 Łódź (Poland)

    2014-09-15

    Highlights: • A. versicolor is able to degrade 4-n-NP as the sole source of carbon and energy. • 4-n-NP removal by A. versicolor was accompanied by the formation of metabolites. • Radioactive experiments show complete 4-n-NP mineralization by A. versicolor. • 4-n-NP initiates heat production in the A. versicolor spores. - Abstract: 4-n-Nonylphenol (4-n-NP) is an environmental pollutant with endocrine-disrupting activities that is formed during the degradation of nonylphenol polyethoxylates, which are widely used as surfactants. Utilization of 4-n-NP by the filamentous fungus Aspergillus versicolor as the sole carbon and energy source was investigated. By means of gas chromatography–mass spectrometry, we showed that in the absence of any carbon source other than 4-n-NP in the medium, A. versicolor completely removed the xenobiotic (100 mg L{sup −1}) after 3 d of cultivation. Moreover, mass spectrometric analysis of intracellular extracts led to the identification of eight intermediates. The mineralization of the xenobiotic in cultures supplemented with 4-n-NP [ring-{sup 14}C(U)] as a growth substrate was also assessed. After 3 d of incubation, approximately 50% of the initially applied radioactivity was recovered in the form of {sup 14}CO{sub 2}, proving that this xenobiotic was completely metabolized and utilized by A. versicolor as a carbon source. Based on microscopic analysis, A. versicolor is capable of germinating spores under such conditions. To confirm these observations, a microcalorimetric method was used. The results show that even the highest amount of 4-n-NP initiates heat production in the fungal samples, proving that metabolic processes were affected by the use of 4-n-NP as an energetic substrate.

  19. Kinetic data base for combustion modeling

    Energy Technology Data Exchange (ETDEWEB)

    Tsang, W.; Herron, J.T. [National Institute of Standards and Technology, Gaithersburg, MD (United States)

    1993-12-01

    The aim of this work is to develop a set of evaluated rate constants for use in the simulation of hydrocarbon combustion. The approach has been to begin with the small molecules and then introduce larger species with the various structural elements that can be found in all hydrocarbon fuels and decomposition products. Currently, the data base contains most of the species present in combustion systems with up to four carbon atoms. Thus, practically all the structural grouping found in aliphatic compounds have now been captured. The direction of future work is the addition of aromatic compounds to the data base.

  20. Growth of Pseudomonas C on C1 compounds: enzyme activites in extracts of Pseudomonas C cells grown on methanol, formaldehyde, and formate as sole carbon sources.

    Science.gov (United States)

    Goldberg, I; Mateles, R I

    1975-01-01

    Pseudomonas C can grow on methanol, formaldehyde, or formate as sole carbon source. It is proposed that the assimilation of carbon by Pseudomonas C grown on different C1 growth substrates proceeds via one of two metabolic pathways, the serine pathway or the allulose pathway (the ribose phosphate cycle of formaldehyde fixation). This contention is based on the distribution of two key enzymes, each of which appears to be specifically involved in one of the assimilation pathways, glycerate dehydrogenase (serine pathway) and hexose phosphate synthetase (allulose pathway). The assimilation of methanol in Pseudomonas C cells appears to occur via the allulose pathway, whereas the utilization of formaldehyde or formate in cells grown on formaldehyde or formate as sole carbon sources appears by the serine pathway. When methanol is present together with formaldehyde or formate in the growth medium, the formaldehyde or formate is utilized by the allulose pathway. PMID:235511

  1. Thermodynamics-based models of transcriptional regulation with gene sequence.

    Science.gov (United States)

    Wang, Shuqiang; Shen, Yanyan; Hu, Jinxing

    2015-12-01

    Quantitative models of gene regulatory activity have the potential to improve our mechanistic understanding of transcriptional regulation. However, the few models available today have been based on simplistic assumptions about the sequences being modeled or heuristic approximations of the underlying regulatory mechanisms. In this work, we have developed a thermodynamics-based model to predict gene expression driven by any DNA sequence. The proposed model relies on a continuous time, differential equation description of transcriptional dynamics. The sequence features of the promoter are exploited to derive the binding affinity which is derived based on statistical molecular thermodynamics. Experimental results show that the proposed model can effectively identify the activity levels of transcription factors and the regulatory parameters. Comparing with the previous models, the proposed model can reveal more biological sense.

  2. Annotation-based feature extraction from sets of SBML models.

    Science.gov (United States)

    Alm, Rebekka; Waltemath, Dagmar; Wolfien, Markus; Wolkenhauer, Olaf; Henkel, Ron

    2015-01-01

    Model repositories such as BioModels Database provide computational models of biological systems for the scientific community. These models contain rich semantic annotations that link model entities to concepts in well-established bio-ontologies such as Gene Ontology. Consequently, thematically similar models are likely to share similar annotations. Based on this assumption, we argue that semantic annotations are a suitable tool to characterize sets of models. These characteristics improve model classification, allow to identify additional features for model retrieval tasks, and enable the comparison of sets of models. In this paper we discuss four methods for annotation-based feature extraction from model sets. We tested all methods on sets of models in SBML format which were composed from BioModels Database. To characterize each of these sets, we analyzed and extracted concepts from three frequently used ontologies, namely Gene Ontology, ChEBI and SBO. We find that three out of the methods are suitable to determine characteristic features for arbitrary sets of models: The selected features vary depending on the underlying model set, and they are also specific to the chosen model set. We show that the identified features map on concepts that are higher up in the hierarchy of the ontologies than the concepts used for model annotations. Our analysis also reveals that the information content of concepts in ontologies and their usage for model annotation do not correlate. Annotation-based feature extraction enables the comparison of model sets, as opposed to existing methods for model-to-keyword comparison, or model-to-model comparison.

  3. Warehouse Optimization Model Based on Genetic Algorithm

    Directory of Open Access Journals (Sweden)

    Guofeng Qin

    2013-01-01

    Full Text Available This paper takes Bao Steel logistics automated warehouse system as an example. The premise is to maintain the focus of the shelf below half of the height of the shelf. As a result, the cost time of getting or putting goods on the shelf is reduced, and the distance of the same kind of goods is also reduced. Construct a multiobjective optimization model, using genetic algorithm to optimize problem. At last, we get a local optimal solution. Before optimization, the average cost time of getting or putting goods is 4.52996 s, and the average distance of the same kinds of goods is 2.35318 m. After optimization, the average cost time is 4.28859 s, and the average distance is 1.97366 m. After analysis, we can draw the conclusion that this model can improve the efficiency of cargo storage.

  4. CSPBuilder - CSP based Scientific Workflow Modelling

    DEFF Research Database (Denmark)

    Friborg, Rune Møllegaard; Vinter, Brian

    2008-01-01

    This paper introduces a framework for building CSP based applications, targeted for clusters and next generation CPU designs. CPUs are produced with several cores today and every future CPU generation will feature increasingly more cores, resulting in a requirement for concurrency that has not pr...

  5. Dynamic Ligand Based Pharmacophore Modeling and Virtual ...

    Indian Academy of Sciences (India)

    user

    QPlogKhsa Prediction of binding to human serum albumin. (–1.5 – 1.5). •. HumanOralAbsorption Predicted qualitative human oral absorption: 1, 2, or 3 for low, medium, or high. •. PercentHuman- OralAbsorption Predicted human oral absorption on 0 to 100% scale. The prediction is based on a quantitative multiple linear ...

  6. Probabilistic Model-based Background Subtraction

    DEFF Research Database (Denmark)

    Krüger, Volker; Anderson, Jakob; Prehn, Thomas

    2005-01-01

    Usually, background subtraction is approached as a pixel-based process, and the output is (a possibly thresholded) image where each pixel reflects, independent from its neighboring pixels, the likelihood of itself belonging to a foreground object. What is neglected for better output is the correl...

  7. Text document classification based on mixture models

    Czech Academy of Sciences Publication Activity Database

    Novovičová, Jana; Malík, Antonín

    2004-01-01

    Roč. 40, č. 3 (2004), s. 293-304 ISSN 0023-5954 R&D Projects: GA AV ČR IAA2075302; GA ČR GA102/03/0049; GA AV ČR KSK1019101 Institutional research plan: CEZ:AV0Z1075907 Keywords : text classification * text categorization * multinomial mixture model Subject RIV: BB - Applied Statistics, Operational Research Impact factor: 0.224, year: 2004

  8. Bacterial chemotaxis: introverted or extroverted? A comparison of the advantages and disadvantages of basic forms of metabolism-based and metabolism-independent behavior using a computational model.

    Science.gov (United States)

    Egbert, Matthew D

    2013-01-01

    Using a minimal model of metabolism, we examine the limitations of behavior that is (a) solely in response to environmental phenomena or (b) solely in response to metabolic dynamics, showing that basic forms of each of these kinds of behavior are incapable of driving survival-prolonging behavior in certain situations. Inspired by experimental evidence of concurrent metabolism-based and metabolism-independent chemotactic mechanisms in Escherichia coli and Rhodobacter sphaeroides, we then investigate how metabolism-independent and metabolism-based sensitivities can be integrated into a single behavioral response, demonstrating that a simple switching mechanism can be sufficient to effectively integrate metabolism-based and metabolism-independent behaviors. Finally, we use a spatial simulation of bacteria to show that the investigated forms of behavior produce different spatio-temporal patterns that are influenced by the metabolic-history of the bacteria. We suggest that these patterns could be a way to experimentally derive insight into the relationship between metabolism and chemotaxis in real bacteria.

  9. Fujisaki Model Based Intonation Modeling for Korean TTS System

    Science.gov (United States)

    Kim, Byeongchang; Lee, Jinsik; Lee, Gary Geunbae

    One of the enduring problems in developing high-quality TTS (text-to-speech) system is pitch contour generation. Considering language specific knowledge, an adjusted Fujisaki model for Korean TTS system is introduced along with refined machine learning features. The results of quantitative and qualitative evaluations show the validity of our system: the accuracy of the phrase command prediction is 0.8928; the correlations of the predicted amplitudes of a phrase command and an accent command are 0.6644 and 0.6002, respectively; our method achieved the level of "fair" naturalness (3.6) in a MOS scale for generated F0 curves.

  10. Weather forecasting based on hybrid neural model

    Science.gov (United States)

    Saba, Tanzila; Rehman, Amjad; AlGhamdi, Jarallah S.

    2017-11-01

    Making deductions and expectations about climate has been a challenge all through mankind's history. Challenges with exact meteorological directions assist to foresee and handle problems well in time. Different strategies have been investigated using various machine learning techniques in reported forecasting systems. Current research investigates climate as a major challenge for machine information mining and deduction. Accordingly, this paper presents a hybrid neural model (MLP and RBF) to enhance the accuracy of weather forecasting. Proposed hybrid model ensure precise forecasting due to the specialty of climate anticipating frameworks. The study concentrates on the data representing Saudi Arabia weather forecasting. The main input features employed to train individual and hybrid neural networks that include average dew point, minimum temperature, maximum temperature, mean temperature, average relative moistness, precipitation, normal wind speed, high wind speed and average cloudiness. The output layer composed of two neurons to represent rainy and dry weathers. Moreover, trial and error approach is adopted to select an appropriate number of inputs to the hybrid neural network. Correlation coefficient, RMSE and scatter index are the standard yard sticks adopted for forecast accuracy measurement. On individual standing MLP forecasting results are better than RBF, however, the proposed simplified hybrid neural model comes out with better forecasting accuracy as compared to both individual networks. Additionally, results are better than reported in the state of art, using a simple neural structure that reduces training time and complexity.

  11. P-T evolution of slivers of garnet-bearing micaschist in the sole of the Western Vardar Ophiolite Unit at Brezovica, Kosovo

    Science.gov (United States)

    Massonne, Hans-Joachim; Koller, Friedrich; Onuzi, Kujtim

    2016-04-01

    at a pressure of 11.5 kbar, which is compatible with the aforementioned talc + phengite assemblage. We think that the recognized HP metamorphism of the studied micaschist was caused by the load of the obducting oceanic lithosphere, which must have been as thick as 35 km. Heating of the overridden rocks during this obduction process resulted in the release of H2O, which hydrated the mantle rocks at the base of the obducting oceanic lithosphere. An alternative model, which assigned the location of the hydration to the mantle wedge overlying a subduction zone, was abandoned also because of the existence of higher levels of oceanic crust, such as pillow lavas, in the preserved oceanic lithosphere close to the Brezovica region.

  12. Model-Driven and Pattern-Based Integration of Process-Driven SOA Models

    OpenAIRE

    Zdun, Uwe; Dustdar, Schahram

    2006-01-01

    Service-oriented architectures (SOA) are increasingly used in the context of business processes. However, the modeling approaches for process-driven SOAs do not yet sufficiently integrate the various kinds of models relevant for a process-driven SOA -- ranging from process models to software architectural models to software design models. We propose to integrate process-driven SOA models via a model-driven software development approach that is based on proven practices do...

  13. Hydrological real-time modelling in the Zambezi river basin using satellite-based soil moisture and rainfall data

    Directory of Open Access Journals (Sweden)

    P. Meier

    2011-03-01

    Full Text Available Reliable real-time forecasts of the discharge can provide valuable information for the management of a river basin system. For the management of ecological releases even discharge forecasts with moderate accuracy can be beneficial. Sequential data assimilation using the Ensemble Kalman Filter provides a tool that is both efficient and robust for a real-time modelling framework. One key parameter in a hydrological system is the soil moisture, which recently can be characterized by satellite based measurements. A forecasting framework for the prediction of discharges is developed and applied to three different sub-basins of the Zambezi River Basin. The model is solely based on remote sensing data providing soil moisture and rainfall estimates. The soil moisture product used is based on the back-scattering intensity of a radar signal measured by a radar scatterometer. These soil moisture data correlate well with the measured discharge of the corresponding watershed if the data are shifted by a time lag which is dependent on the size and the dominant runoff process in the catchment. This time lag is the basis for the applicability of the soil moisture data for hydrological forecasts. The conceptual model developed is based on two storage compartments. The processes modeled include evaporation losses, infiltration and percolation. The application of this model in a real-time modelling framework yields good results in watersheds where soil storage is an important factor. The lead time of the forecast is dependent on the size and the retention capacity of the watershed. For the largest watershed a forecast over 40 days can be provided. However, the quality of the forecast increases significantly with decreasing prediction time. In a watershed with little soil storage and a quick response to rainfall events, the performance is relatively poor and the lead time is as short as 10 days only.

  14. Towards automatic model based controller design for reconfigurable plants

    DEFF Research Database (Denmark)

    Michelsen, Axel Gottlieb; Stoustrup, Jakob; Izadi-Zamanabadi, Roozbeh

    2008-01-01

    This paper introduces model-based Plug and Play Process Control, a novel concept for process control, which allows a model-based control system to be reconfigured when a sensor or an actuator is plugged into a controlled process. The work reported in this paper focuses on composing a monolithic m...

  15. Assessment of Energy Efficient and Model Based Control

    Science.gov (United States)

    2017-06-15

    ARL-TR-8042 ● JUNE 2017 US Army Research Laboratory Assessment of Energy -Efficient and Model- Based Control by Craig Lennon...originator. ARL-TR-8042 ● JUNE 2017 US Army Research Laboratory Assessment of Energy -Efficient and Model- Based Control by Craig...

  16. Agent-based modelling of socio-technical systems

    CERN Document Server

    van Dam, Koen H; Lukszo, Zofia

    2012-01-01

    Here is a practical introduction to agent-based modelling of socio-technical systems, based on methodology developed at TU Delft, which has been deployed in a number of case studies. Offers theory, methods and practical steps for creating real-world models.

  17. Facilitating Change to a Problem-based Model

    DEFF Research Database (Denmark)

    Kolmos, Anette

    2002-01-01

    The paper presents the barriers which arise during the change process from a traditional educational system to a problem-based educational model.......The paper presents the barriers which arise during the change process from a traditional educational system to a problem-based educational model....

  18. Model-Based Software Testing for Object-Oriented Software

    Science.gov (United States)

    Biju, Soly Mathew

    2008-01-01

    Model-based testing is one of the best solutions for testing object-oriented software. It has a better test coverage than other testing styles. Model-based testing takes into consideration behavioural aspects of a class, which are usually unchecked in other testing methods. An increase in the complexity of software has forced the software industry…

  19. Model-reduced gradient-based history matching

    NARCIS (Netherlands)

    Kaleta, M.P.

    2011-01-01

    Since the world's energy demand increases every year, the oil & gas industry makes a continuous effort to improve fossil fuel recovery. Physics-based petroleum reservoir modeling and closed-loop model-based reservoir management concept can play an important role here. In this concept measured data

  20. Software Reuse of Mobile Systems based on Modelling

    Directory of Open Access Journals (Sweden)

    Guo Ping

    2016-01-01

    Full Text Available This paper presents an architectural style based modelling approach for architectural design, analysis of mobile systems. The approach is developed based on UML-like meta models and graph transformation techniques to support sound methodological principals, formal analysis and refinement. The approach could support mobile system development.

  1. A Technology-based Model for Learning

    Directory of Open Access Journals (Sweden)

    Michael Williams

    2004-12-01

    Full Text Available The Math Emporium, opened in 1997, is an open 7000-squaremeter facility with 550+ workstations arranged in an array of widely spaced hexagonal "pods", designed to support group work at the same time maintaining an academic air. We operate it 24/7 with math support personnel in attendance 12 hours per day. Students have access to online course resources at all times, from anywhere. We have used this unique asset to transform traditional classroom-based courses into technology based learning programs that have no class meetings at all. The structure of the program is very different from the conventional one, having a new set of expectations and motivations. The results include: more effective students, substantial cost savings, economies of scale and scope and a stream-lined process for creating new on-line courses.

  2. Infrared dermal thermography on diabetic feet soles to predict ulcerations: a case study

    Science.gov (United States)

    Liu, Chanjuan; van der Heijden, Ferdi; Klein, Marvin E.; van Baal, Jeff G.; Bus, Sicco A.; van Netten, Jaap J.

    2013-03-01

    Diabetic foot ulceration is a major complication for patients with diabetes mellitus. If not adequately treated, these ulcers may lead to foot infection, and ultimately to lower extremity amputation, which imposes a major burden to society and great loss in health-related quality of life for patients. Early identification and subsequent preventive treatment have proven useful to limit the incidence of foot ulcers and lower extremity amputation. Thus, the development of new diagnosis tools has become an attractive option. The ultimate objective of our project is to develop an intelligent telemedicine monitoring system for frequent examination on patients' feet, to timely detect pre-signs of ulceration. Inflammation in diabetic feet can be an early and predictive warning sign for ulceration, and temperature has been proven to be a vicarious marker for inflammation. Studies have indicated that infrared dermal thermography of foot soles can be one of the important parameters for assessing the risk of diabetic foot ulceration. This paper covers the feasibility study of using an infrared camera, FLIR SC305, in our setup, to acquire the spatial thermal distribution on the feet soles. With the obtained thermal images, automated detection through image analysis was performed to identify the abnormal increased/decreased temperature and assess the risk for ulceration. The thermography for feet soles of patients with diagnosed diabetic foot complications were acquired before the ordinary foot examinations. Assessment from clinicians and thermography were compared and follow-up measurements were performed to investigate the prediction. A preliminary case study will be presented, indicating that dermal thermography in our proposed setup can be a screening modality to timely detect pre-signs of ulceration.

  3. Reproductive ethogram and mate selection in captive wild Senegalese sole (Solea senegalensis)

    International Nuclear Information System (INIS)

    Carazo, I.; Chereguini, O.; Martín, I.; Huntingford, F.; Duncan, N.

    2016-01-01

    Senegalese e sole (Solea senegalensis) have a high potential for aquaculture that is hampered by reproductive behavioural problems. These problems result in limited breeder participation in spawning. The present study provided an ethogram and described mate selection and spawning of captive wild Senegalese sole. Two tanks of breeders were studied that had 29 and 25 breeders (mean weight = 1.6 ± 0.1 kg). The behaviour was studied during 20 periods of 24 hours: 10 periods where spawning events were recorded and 10 control periods without spawning events. Periods where spawning occurred had three times more locomotor activity than periods without spawning. Two distinct behaviours, termed the “following” behaviour and the “coupled swim”, were only observed during periods with spawning. The courtship sequence (n=12) began with males predominantly involved in “following” behaviours, whilst females remained mainly stationary on the bottom of the tank. Males rested on the females and encouraged the females to begin swimming. When the female began to swim the male swam under the female and the pair made a “coupled swim” to the surface to release gametes. Gamete release was strictly in pairs of one male with one female. Failed “coupled swims” without gamete release were 5.6 times more frequent than successful “coupled swims”. Mate selection was evident as the sole engaged in: paired spawning, males displayed to females, males encouraged females to spawn and females accepted or rejected the male’s advances. The mate selection process provided the opportunity for fish to dominate the spawning and also demonstrated how fish were excluded from spawning.

  4. Reproductive ethogram and mate selection in captive wild Senegalese sole (Solea senegalensis)

    Energy Technology Data Exchange (ETDEWEB)

    Carazo, I.; Chereguini, O.; Martín, I.; Huntingford, F.; Duncan, N.

    2016-07-01

    Senegalese e sole (Solea senegalensis) have a high potential for aquaculture that is hampered by reproductive behavioural problems. These problems result in limited breeder participation in spawning. The present study provided an ethogram and described mate selection and spawning of captive wild Senegalese sole. Two tanks of breeders were studied that had 29 and 25 breeders (mean weight = 1.6 ± 0.1 kg). The behaviour was studied during 20 periods of 24 hours: 10 periods where spawning events were recorded and 10 control periods without spawning events. Periods where spawning occurred had three times more locomotor activity than periods without spawning. Two distinct behaviours, termed the “following” behaviour and the “coupled swim”, were only observed during periods with spawning. The courtship sequence (n=12) began with males predominantly involved in “following” behaviours, whilst females remained mainly stationary on the bottom of the tank. Males rested on the females and encouraged the females to begin swimming. When the female began to swim the male swam under the female and the pair made a “coupled swim” to the surface to release gametes. Gamete release was strictly in pairs of one male with one female. Failed “coupled swims” without gamete release were 5.6 times more frequent than successful “coupled swims”. Mate selection was evident as the sole engaged in: paired spawning, males displayed to females, males encouraged females to spawn and females accepted or rejected the male’s advances. The mate selection process provided the opportunity for fish to dominate the spawning and also demonstrated how fish were excluded from spawning.

  5. Influence of ontogenetic and environmental changes in the otolith microchemistry of juvenile sole ( Solea solea)

    Science.gov (United States)

    de Pontual, Hélène; Lagardère, Françoise; Amara, Rachid; Bohn, Marcel; Ogor, André

    2003-11-01

    We analysed otolith composition, specifically Sr/Ca ratios, with the aim of determining whether metamorphosis and the transition to benthic life of Bay of Biscay sole occur in marine or estuarine conditions. Otoliths of wild juveniles (0-group) collected in two estuarine nurseries showed characteristic Sr/Ca chronologies, with a significant decrease of the Sr/Ca ratio from the core to the accessory growth centres. As the otolith Sr/Ca ratio decreases in respect of the ambient salinity, this could suggest a relative synchronism in the timing of estuarine nursery entrance. In order to validate this hypothesis, hatchery-produced larvae were reared in a tidal marsh mesocosm until they completed metamorphosis (around 1 month post-hatching) and settled on the bottom. The otoliths from these juveniles exhibited a similar Sr/Ca pattern, which could not be explained as a result of habitat changes, and especially salinity variations, but rather reflected an ontogenetic signal. Since both wild and reared soles achieved high growth rates during metamorphosis, this suggests a link between a high metabolic rate and the observed Sr/Ca drop. In addition, ontogenetic changes during this transitional phase could involve the setting of functional mechanisms, responsible for the regulation of free Sr 2+ in either plasma or endolymph or both. Nevertheless, this common trend appeared to be modulated by environmental cues: Sr/Ca ratios were significantly higher for reared fish compared to wild fish during the larval period. A possible explanation is that experienced temperatures were much higher in the incubator than in the field. Furthermore, Sr/Ca values obtained in the otolith juvenile area, with the lowest ratios for soles from the Loire nursery, suggest that the salinity regime of estuarine nurseries could exert an environmental control on otolith Sr/Ca ratios, thus providing ecological records of up-estuary migration after metamorphosis.

  6. Seismic Model-Based Inversion Using Matlab

    OpenAIRE

    Leite, Emilson Pereira

    2010-01-01

    A simple methodology for mapping acoustic impedance and effective porosity from 3D seismic amplitude data using Matlab® was presented. This methodology can be used for a quick evaluation of reservoir properties, especially when powerful commercial programs are not available. An example with real data was also presented, showing that consistent 3D acoustic impedance models can be obtained if well-logs and 3D seismic data are available. A further improvement would be to obtain the low-frequenc...

  7. Graph-based modelling in engineering

    CERN Document Server

    Rysiński, Jacek

    2017-01-01

    This book presents versatile, modern and creative applications of graph theory in mechanical engineering, robotics and computer networks. Topics related to mechanical engineering include e.g. machine and mechanism science, mechatronics, robotics, gearing and transmissions, design theory and production processes. The graphs treated are simple graphs, weighted and mixed graphs, bond graphs, Petri nets, logical trees etc. The authors represent several countries in Europe and America, and their contributions show how different, elegant, useful and fruitful the utilization of graphs in modelling of engineering systems can be. .

  8. Factors increasing the likelihood of sole and dual charging of women for intimate partner violence.

    Science.gov (United States)

    Poon, Julie; Dawson, Myrna; Morton, Mavis

    2014-12-01

    Sole and dual charging of women for intimate partner violence (IPV) has risen in some Canadian and American jurisdictions since the implementation of pro-charging policies. Adding to the limited research within Canada by examining court cases from a small, Ontario city, sociodemographic and situational characteristics are assessed to determine if the context in which women were charged differs from that of men, or in which dual charges were laid. Women were more likely to be charged if they were younger, in legal or common-law relationships, and in rural jurisdictions. Dual charging was more likely among women in current and dating relationships. © The Author(s) 2014.

  9. A simple melatonin treatment protocol attenuates the response to acute stress in the sole Solea senegalensis

    DEFF Research Database (Denmark)

    Gesto, Manuel; Álvarez-Otero, Rosa; Conde-Sieira, Marta

    2016-01-01

    Several compounds have been tested in fish in order to attenuate the effects of different stressors, most often following previous observations in mammals. The hormone melatonin (MEL) and the amino acid L-tryptophan have been tested for this purpose with different degree of success. In Senegalese...... sole (Solea senegalensis) we have previously observed that during prolonged exposure to relatively mild stressors, the presence of MEL in the water helped to reduce the stress response. Here, we aimed to investigate the potential anti-stress effects of a short melatonin exposure that could be easily...

  10. Sole stenting treatment for small wide-necked saccular intracranial aneurysms:a clinical therapeutic analysis

    International Nuclear Information System (INIS)

    Cheng Jiyong; Hong Bo; Xu Yi; Huang Qinghai; Yang Pengfei; Zhao Wenyuan; Liu Jianmin

    2010-01-01

    Objective: To discuss the feasibility, safety and efficacy of sole stenting technique for the treatment of small wide-necked saccular intracranial aneurysms. Methods: Between February 2001 and November 2009, 36 consecutive patients with small wide-necked saccular intracranial aneurysms (18 males and 18 females, aged 19-75 years,with a mean age of 52.3 years) were treated with stenting technique only. Of 36 patients, the Grade 0 of Hunt and Hess classification was seen in 22,Grade I in 8, Grade II in 5 and Grade III in 1. The aneurysmal diameter ranged from 1.8 mm to 5.0 mm,with a mean diameter of 3.6 mm. The aneurysms were located at the anterior communicating artery (n=1), posterior communicating artery (n=11), intradural paraclinoid internal carotid artery (n=18), basilar artery (n=1), anterior choroidal artery (n=4) or middle cerebral artery (n=1). The clinical manifestations, the angiographic findings and the follow-up observations were analyzed and the results were evaluated by means of the Modified Rankin Scale, magnetic resonance angiography and digital subtraction angiography. Results: Sole stenting treatment was performed in 36 patients with small wide-necked saccular intracranial aneurysms. A total of 37 stents were successfully delivered and deployed at the targeted location. Immediate post-procedural angiography showed that complete occlusion was obtained in one aneurysm, a sluggish intra-aneurysmal vortex motion in 3 aneurysms and a correction of the angle of the parent vessel in two cases, whereas no change was seen in the remaining 30 aneurysms. Angiographic follow-up was carried out in 22 of the 36 patients (61%) during a mean following-up period of 16 months (ranged from 3 to 59 months). The follow-up angiography showed that the complete occlusion was seen in 11 cases, narrowed aneurysmal neck with shrinkage of the aneurysm in 9 cases, narrowed aneurysmal neck only in 1 case, and shrinkage of the aneurysm only in 1 case.All the patients remained

  11. Changes in Liver Proteome Expression of Senegalese Sole (Solea senegalensis) in Response to Repeated Handling Stress

    DEFF Research Database (Denmark)

    Cordeiro, O. D.; Silva, Tomé Santos; Alves, R. N.

    2012-01-01

    , cathepsin B, disulfide-isomerase A3 precursor, cell-division cycle 48, and five distinct heat shock proteins), amino acid metabolism, urea cycle and methylation/folate pathways (methionine adenosyltransferase I α, phenylalanine hydroxylase, mitochondrial agmatinase, serine hydroxymethyltransferase, 3......The Senegalese sole, a high-value flatfish, is a good candidate for aquaculture production. Nevertheless, there are still issues regarding this species’ sensitivity to stress in captivity. We aimed to characterize the hepatic proteome expression for this species in response to repeated handling...

  12. Component-based event composition modeling for CPS

    Science.gov (United States)

    Yin, Zhonghai; Chu, Yanan

    2017-06-01

    In order to combine event-drive model with component-based architecture design, this paper proposes a component-based event composition model to realize CPS’s event processing. Firstly, the formal representations of component and attribute-oriented event are defined. Every component is consisted of subcomponents and the corresponding event sets. The attribute “type” is added to attribute-oriented event definition so as to describe the responsiveness to the component. Secondly, component-based event composition model is constructed. Concept lattice-based event algebra system is built to describe the relations between events, and the rules for drawing Hasse diagram are discussed. Thirdly, as there are redundancies among composite events, two simplification methods are proposed. Finally, the communication-based train control system is simulated to verify the event composition model. Results show that the event composition model we have constructed can be applied to express composite events correctly and effectively.

  13. [Model-based biofuels system analysis: a review].

    Science.gov (United States)

    Chang, Shiyan; Zhang, Xiliang; Zhao, Lili; Ou, Xunmin

    2011-03-01

    Model-based system analysis is an important tool for evaluating the potential and impacts of biofuels, and for drafting biofuels technology roadmaps and targets. The broad reach of the biofuels supply chain requires that biofuels system analyses span a range of disciplines, including agriculture/forestry, energy, economics, and the environment. Here we reviewed various models developed for or applied to modeling biofuels, and presented a critical analysis of Agriculture/Forestry System Models, Energy System Models, Integrated Assessment Models, Micro-level Cost, Energy and Emission Calculation Models, and Specific Macro-level Biofuel Models. We focused on the models' strengths, weaknesses, and applicability, facilitating the selection of a suitable type of model for specific issues. Such an analysis was a prerequisite for future biofuels system modeling, and represented a valuable resource for researchers and policy makers.

  14. Radiobiological analyse based on cell cluster models

    International Nuclear Information System (INIS)

    Lin Hui; Jing Jia; Meng Damin; Xu Yuanying; Xu Liangfeng

    2010-01-01

    The influence of cell cluster dimension on EUD and TCP for targeted radionuclide therapy was studied using the radiobiological method. The radiobiological features of tumor with activity-lack in core were evaluated and analyzed by associating EUD, TCP and SF.The results show that EUD will increase with the increase of tumor dimension under the activity homogeneous distribution. If the extra-cellular activity was taken into consideration, the EUD will increase 47%. Under the activity-lack in tumor center and the requirement of TCP=0.90, the α cross-fire influence of 211 At could make up the maximum(48 μm)3 activity-lack for Nucleus source, but(72 μm)3 for Cytoplasm, Cell Surface, Cell and Voxel sources. In clinic,the physician could prefer the suggested dose of Cell Surface source in case of the future of local tumor control for under-dose. Generally TCP could well exhibit the effect difference between under-dose and due-dose, but not between due-dose and over-dose, which makes TCP more suitable for the therapy plan choice. EUD could well exhibit the difference between different models and activity distributions,which makes it more suitable for the research work. When the user uses EUD to study the influence of activity inhomogeneous distribution, one should keep the consistency of the configuration and volume of the former and the latter models. (authors)

  15. Model based analysis of piezoelectric transformers.

    Science.gov (United States)

    Hemsel, T; Priya, S

    2006-12-22

    Piezoelectric transformers are increasingly getting popular in the electrical devices owing to several advantages such as small size, high efficiency, no electromagnetic noise and non-flammable. In addition to the conventional applications such as ballast for back light inverter in notebook computers, camera flash, and fuel ignition several new applications have emerged such as AC/DC converter, battery charger and automobile lighting. These new applications demand high power density and wide range of voltage gain. Currently, the transformer power density is limited to 40 W/cm(3) obtained at low voltage gain. The purpose of this study was to investigate a transformer design that has the potential of providing higher power density and wider range of voltage gain. The new transformer design utilizes radial mode both at the input and output port and has the unidirectional polarization in the ceramics. This design was found to provide 30 W power with an efficiency of 98% and 30 degrees C temperature rise from the room temperature. An electro-mechanical equivalent circuit model was developed to describe the characteristics of the piezoelectric transformer. The model was found to successfully predict the characteristics of the transformer. Excellent matching was found between the computed and experimental results. The results of this study will allow to deterministically design unipoled piezoelectric transformers with specified performance. It is expected that in near future the unipoled transformer will gain significant importance in various electrical components.

  16. Sensitivity-Based Guided Model Calibration

    Science.gov (United States)

    Semnani, M.; Asadzadeh, M.

    2017-12-01

    A common practice in automatic calibration of hydrologic models is applying the sensitivity analysis prior to the global optimization to reduce the number of decision variables (DVs) by identifying the most sensitive ones. This two-stage process aims to improve the optimization efficiency. However, Parameter sensitivity information can be used to enhance the ability of the optimization algorithms to find good quality solutions in a fewer number of solution evaluations. This improvement can be achieved by increasing the focus of optimization on sampling from the most sensitive parameters in each iteration. In this study, the selection process of the dynamically dimensioned search (DDS) optimization algorithm is enhanced by utilizing a sensitivity analysis method to put more emphasis on the most sensitive decision variables for perturbation. The performance of DDS with the sensitivity information is compared to the original version of DDS for different mathematical test functions and a model calibration case study. Overall, the results show that DDS with sensitivity information finds nearly the same solutions as original DDS, however, in a significantly fewer number of solution evaluations.

  17. IDEF method-based simulation model design and development framework

    Directory of Open Access Journals (Sweden)

    Ki-Young Jeong

    2009-09-01

    Full Text Available The purpose of this study is to provide an IDEF method-based integrated framework for a business process simulation model to reduce the model development time by increasing the communication and knowledge reusability during a simulation project. In this framework, simulation requirements are collected by a function modeling method (IDEF0 and a process modeling method (IDEF3. Based on these requirements, a common data model is constructed using the IDEF1X method. From this reusable data model, multiple simulation models are automatically generated using a database-driven simulation model development approach. The framework is claimed to help both requirement collection and experimentation phases during a simulation project by improving system knowledge, model reusability, and maintainability through the systematic use of three descriptive IDEF methods and the features of the relational database technologies. A complex semiconductor fabrication case study was used as a testbed to evaluate and illustrate the concepts and the framework. Two different simulation software products were used to develop and control the semiconductor model from the same knowledge base. The case study empirically showed that this framework could help improve the simulation project processes by using IDEF-based descriptive models and the relational database technology. Authors also concluded that this framework could be easily applied to other analytical model generation by separating the logic from the data.

  18. MAC/FAC: A Model of Similarity-Based Retrieval.

    Science.gov (United States)

    Forbus, Kenneth D.; And Others

    1995-01-01

    Presents MAC/FAC, a model of similarity-based retrieval that attempts to capture psychological phenomena; discusses its limitations and extensions, its relationship with other retrieval models, and its placement in the context of other work on the nature of similarity. Examines the utility of the model through psychological experiments and…

  19. A DSM-based framework for integrated function modelling

    DEFF Research Database (Denmark)

    Eisenbart, Boris; Gericke, Kilian; Blessing, Lucienne T. M.

    2017-01-01

    an integrated function modelling framework, which specifically aims at relating between the different function modelling perspectives prominently addressed in different disciplines. It uses interlinked matrices based on the concept of DSM and MDM in order to facilitate cross-disciplinary modelling and analysis...

  20. The evolution of process-based hydrologic models

    NARCIS (Netherlands)

    Clark, Martyn P.; Bierkens, Marc F.P.; Samaniego, Luis; Woods, Ross A.; Uijlenhoet, Remko; Bennett, Katrina E.; Pauwels, Valentijn R.N.; Cai, Xitian; Wood, Andrew W.; Peters-Lidard, Christa D.

    2017-01-01

    The diversity in hydrologic models has historically led to great controversy on the "correct" approach to process-based hydrologic modeling, with debates centered on the adequacy of process parameterizations, data limitations and uncertainty, and computational constraints on model analysis. In this

  1. Model-Based Traffic Control for Sustainable Mobility

    NARCIS (Netherlands)

    Zegeye, S.K.

    2011-01-01

    Computationally efficient dynamic fuel consumption, emissions, and dispersion of emissions models are developed. Fast and practically feasible model-based controller is proposed. Using the developed models, the controller steers the traffic flow in such a way that a balanced trade-off between the

  2. A Physically-Motivated Deformable Model Based on Fluid Dynamics

    NARCIS (Netherlands)

    Jalba, Andrei C.; Roerdink, Jos B.T.M.; Leonardis, A; Bischof, H; Pinz, A

    2006-01-01

    A novel deformable model for image segmentation and shape recovery is presented. The model is inspired by fluid dynamics and is based on a flooding simulation similar to the watershed paradigm. Unlike most watershed methods, our model has a continuous formulation, being described by two partial

  3. Online Knowledge-Based Model for Big Data Topic Extraction

    Science.gov (United States)

    Khan, Muhammad Taimoor; Durrani, Mehr; Khalid, Shehzad; Aziz, Furqan

    2016-01-01

    Lifelong machine learning (LML) models learn with experience maintaining a knowledge-base, without user intervention. Unlike traditional single-domain models they can easily scale up to explore big data. The existing LML models have high data dependency, consume more resources, and do not support streaming data. This paper proposes online LML model (OAMC) to support streaming data with reduced data dependency. With engineering the knowledge-base and introducing new knowledge features the learning pattern of the model is improved for data arriving in pieces. OAMC improves accuracy as topic coherence by 7% for streaming data while reducing the processing cost to half. PMID:27195004

  4. Model based control of dynamic atomic force microscope

    International Nuclear Information System (INIS)

    Lee, Chibum; Salapaka, Srinivasa M.

    2015-01-01

    A model-based robust control approach is proposed that significantly improves imaging bandwidth for the dynamic mode atomic force microscopy. A model for cantilever oscillation amplitude and phase dynamics is derived and used for the control design. In particular, the control design is based on a linearized model and robust H ∞ control theory. This design yields a significant improvement when compared to the conventional proportional-integral designs and verified by experiments

  5. The role of model based control in robotics

    International Nuclear Information System (INIS)

    Harrigan, R.W.

    1990-01-01

    This paper discusses the use of model based control of industrial robots. Computer models of the robots and their operating environments are complemented with environmental sensing. This allows automatic programming of robot trajectories, hybrid force/position control and computer assist during manual operation. In addition, sensors detect error situations which may require operator attention prior to continued system operation.Computer models are also used to verify the validity of sensor data before the robotic system executes operations based upon those data

  6. Fuzzy model-based control of a nuclear reactor

    International Nuclear Information System (INIS)

    Van Den Durpel, L.; Ruan, D.

    1994-01-01

    The fuzzy model-based control of a nuclear power reactor is an emerging research topic world-wide. SCK-CEN is dealing with this research in a preliminary stage, including two aspects, namely fuzzy control and fuzzy modelling. The aim is to combine both methodologies in contrast to conventional model-based PID control techniques, and to state advantages of including fuzzy parameters as safety and operator feedback. This paper summarizes the general scheme of this new research project

  7. Model-based Sensor Data Acquisition and Management

    OpenAIRE

    Aggarwal, Charu C.; Sathe, Saket; Papaioannou, Thanasis G.; Jeung, Ho Young; Aberer, Karl

    2012-01-01

    In recent years, due to the proliferation of sensor networks, there has been a genuine need of researching techniques for sensor data acquisition and management. To this end, a large number of techniques have emerged that advocate model-based sensor data acquisition and management. These techniques use mathematical models for performing various, day-to-day tasks involved in managing sensor data. In this chapter, we survey the state-of-the-art techniques for model-based sensor data acquisition...

  8. Model based control of dynamic atomic force microscope.

    Science.gov (United States)

    Lee, Chibum; Salapaka, Srinivasa M

    2015-04-01

    A model-based robust control approach is proposed that significantly improves imaging bandwidth for the dynamic mode atomic force microscopy. A model for cantilever oscillation amplitude and phase dynamics is derived and used for the control design. In particular, the control design is based on a linearized model and robust H(∞) control theory. This design yields a significant improvement when compared to the conventional proportional-integral designs and verified by experiments.

  9. Model and Behavior-Based Robotic Goalkeeper

    DEFF Research Database (Denmark)

    Lausen, H.; Nielsen, J.; Nielsen, M.

    2003-01-01

    This paper describes the design, implementation and test of a goalkeeper robot for the Middle-Size League of RoboCub. The goalkeeper task is implemented by a set of primitive tasks and behaviours coordinated by a 2-level hierarchical state machine. The primitive tasks concerning complex motion...... control are implemented by a non-linear control algorithm, adapted to the different task goals (e.g., follow the ball or the robot posture from local features extracted from images acquired by a catadioptric omni-directional vision system. Most robot parameters were designed based on simulations carried...

  10. Spatial analysis and modelling based on activities

    CSIR Research Space (South Africa)

    Conradie, Dirk CU

    2010-01-01

    Full Text Available of the year where visibility on the road near sunrise and sunset would be severely impaired, possibly contributing to accidents. One of the advantages of a visual based simulation is that non-technical role players can visualise problems and it enables them... to work with professional, scientific and technical designers. The vector graphic part of the simulation environment can be conveniently built by means of standard CAD programs such as AutoCAD, AutoDesk Revit, 3D Studio Max or MicroGDS. Although...

  11. Model based image restoration for underwater images

    Science.gov (United States)

    Stephan, Thomas; Frühberger, Peter; Werling, Stefan; Heizmann, Michael

    2013-04-01

    The inspection of offshore parks, dam walls and other infrastructure under water is expensive and time consuming, because such constructions must be inspected manually by divers. Underwater buildings have to be examined visually to find small cracks, spallings or other deficiencies. Automation of underwater inspection depends on established water-proved imaging systems. Most underwater imaging systems are based on acoustic sensors (sonar). The disadvantage of such an acoustic system is the loss of the complete visual impression. All information embedded in texture and surface reflectance gets lost. Therefore acoustic sensors are mostly insufficient for these kind of visual inspection tasks. Imaging systems based on optical sensors feature an enormous potential for underwater applications. The bandwidth from visual imaging systems reach from inspection of underwater buildings via marine biological applications through to exploration of the seafloor. The reason for the lack of established optical systems for underwater inspection tasks lies in technical difficulties of underwater image acquisition and processing. Lightening, highly degraded images make a computational postprocessing absolutely essential.

  12. System Dynamics as Model-Based Theory Building

    OpenAIRE

    Schwaninger, Markus; Grösser, Stefan N.

    2008-01-01

    This paper introduces model-based theory building as a feature of system dynamics (SD) with large potential. It presents a systemic approach to actualizing that potential, thereby opening up a new perspective on theory building in the social sciences. The question addressed is if and how SD enables the construction of high-quality theories. This contribution is based on field experiment type projects which have been focused on model-based theory building, specifically the construction of a mi...

  13. Repetition-based Interactive Facade Modeling

    KAUST Repository

    AlHalawani, Sawsan

    2012-07-01

    Modeling and reconstruction of urban environments has gained researchers attention throughout the past few years. It spreads in a variety of directions across multiple disciplines such as image processing, computer graphics and computer vision as well as in architecture, geoscience and remote sensing. Having a virtual world of our real cities is very attractive in various directions such as entertainment, engineering, governments among many others. In this thesis, we address the problem of processing a single fa cade image to acquire useful information that can be utilized to manipulate the fa cade and generate variations of fa cade images which can be later used for buildings\\' texturing. Typical fa cade structures exhibit a rectilinear distribution where in windows and other elements are organized in a grid of horizontal and vertical repetitions of similar patterns. In the firt part of this thesis, we propose an efficient algorithm that exploits information obtained from a single image to identify the distribution grid of the dominant elements i.e. windows. This detection method is initially assisted with the user marking the dominant window followed by an automatic process for identifying its repeated instances which are used to define the structure grid. Given the distribution grid, we allow the user to interactively manipulate the fa cade by adding, deleting, resizing or repositioning the windows in order to generate new fa cade structures. Having the utility for the interactive fa cade is very valuable to create fa cade variations and generate new textures for building models. Ultimately, there is a wide range of interesting possibilities of interactions to be explored.

  14. Sole depth and weight-bearing characteristics of the palmar surface of the feet of feral horses and domestic Thoroughbreds.

    Science.gov (United States)

    Hampson, Brian A; Connelley, Alexandra D; de Laat, Melody A; Mills, Paul C; Pollitt, Chris C

    2011-06-01

    To determine solar load-bearing structures in the feet of feral horses and investigate morphological characteristics of the sole in feral horses and domestic Thoroughbreds. Forelimbs from cadavers of 70 feral horses and 20 domestic Thoroughbreds in Australia. Left forefeet were obtained from 3 feral horse populations from habitats of soft substrate (SS [n = 10 horses]), hard substrate (HS [10]), and a combination of SS and HS (10) and loaded in vitro. Pressure distribution was measured with a pressure plate. Sole depth was measured at 12 points across the solar plane in feet obtained from feral horses from SS (n = 20 horses) and HS (20) habitats and domestic Thoroughbreds (20). Feet of feral horses from HS habitats loaded the periphery of the sole and hoof wall on a flat surface. Feral horses from HS or SS habitats had greater mean sole depth than did domestic Thoroughbreds. Sole depth was greatest peripherally and was correlated with the loading pattern. The peripheral aspect of the sole in the feet of feral horses had a load-bearing function. Because of the robust nature of the tissue architecture, the hoof capsule of feral horses may be less flexible than that of typical domestic horses. The application of narrow-web horseshoes may not take full advantage of the load-bearing and force-dissipating properties of the peripheral aspect of the sole. Further studies are required to understand the effects of biomechanical stimulation on the adaptive responses of equine feet.

  15. Guidelines for visualizing and annotating rule-based models.

    Science.gov (United States)

    Chylek, Lily A; Hu, Bin; Blinov, Michael L; Emonet, Thierry; Faeder, James R; Goldstein, Byron; Gutenkunst, Ryan N; Haugh, Jason M; Lipniacki, Tomasz; Posner, Richard G; Yang, Jin; Hlavacek, William S

    2011-10-01

    Rule-based modeling provides a means to represent cell signaling systems in a way that captures site-specific details of molecular interactions. For rule-based models to be more widely understood and (re)used, conventions for model visualization and annotation are needed. We have developed the concepts of an extended contact map and a model guide for illustrating and annotating rule-based models. An extended contact map represents the scope of a model by providing an illustration of each molecule, molecular component, direct physical interaction, post-translational modification, and enzyme-substrate relationship considered in a model. A map can also illustrate allosteric effects, structural relationships among molecular components, and compartmental locations of molecules. A model guide associates elements of a contact map with annotation and elements of an underlying model, which may be fully or partially specified. A guide can also serve to document the biological knowledge upon which a model is based. We provide examples of a map and guide for a published rule-based model that characterizes early events in IgE receptor (FcεRI) signaling. We also provide examples of how to visualize a variety of processes that are common in cell signaling systems but not considered in the example model, such as ubiquitination. An extended contact map and an associated guide can document knowledge of a cell signaling system in a form that is visual as well as executable. As a tool for model annotation, a map and guide can communicate the content of a model clearly and with precision, even for large models.

  16. Model-Drive Architecture for Agent-Based Systems

    Science.gov (United States)

    Gradanin, Denis; Singh, H. Lally; Bohner, Shawn A.; Hinchey, Michael G.

    2004-01-01

    The Model Driven Architecture (MDA) approach uses a platform-independent model to define system functionality, or requirements, using some specification language. The requirements are then translated to a platform-specific model for implementation. An agent architecture based on the human cognitive model of planning, the Cognitive Agent Architecture (Cougaar) is selected for the implementation platform. The resulting Cougaar MDA prescribes certain kinds of models to be used, how those models may be prepared and the relationships of the different kinds of models. Using the existing Cougaar architecture, the level of application composition is elevated from individual components to domain level model specifications in order to generate software artifacts. The software artifacts generation is based on a metamodel. Each component maps to a UML structured component which is then converted into multiple artifacts: Cougaar/Java code, documentation, and test cases.

  17. A community-based framework for aquatic ecosystem models

    DEFF Research Database (Denmark)

    Trolle, Didde; Hamilton, D. P.; Hipsey, M. R.

    2012-01-01

    a literature survey, we document the growing importance of numerical aquatic ecosystem models while also noting the difficulties, up until now, of the aquatic scientific community to make significant advances in these models during the past two decades. Through a common forum for aquatic ecosystem modellers we......Here, we communicate a point of departure in the development of aquatic ecosystem models, namely a new community-based framework, which supports an enhanced and transparent union between the collective expertise that exists in the communities of traditional ecologists and model developers. Through...... aim to (i) advance collaboration within the aquatic ecosystem modelling community, (ii) enable increased use of models for research, policy and ecosystem-based management, (iii) facilitate a collective framework using common (standardised) code to ensure that model development is incremental, (iv...

  18. Rule-based models of the interplay between genetic and environmental factors in childhood allergy.

    Directory of Open Access Journals (Sweden)

    Susanne Bornelöv

    Full Text Available Both genetic and environmental factors are important for the development of allergic diseases. However, a detailed understanding of how such factors act together is lacking. To elucidate the interplay between genetic and environmental factors in allergic diseases, we used a novel bioinformatics approach that combines feature selection and machine learning. In two materials, PARSIFAL (a European cross-sectional study of 3113 children and BAMSE (a Swedish birth-cohort including 2033 children, genetic variants as well as environmental and lifestyle factors were evaluated for their contribution to allergic phenotypes. Monte Carlo feature selection and rule based models were used to identify and rank rules describing how combinations of genetic and environmental factors affect the risk of allergic diseases. Novel interactions between genes were suggested and replicated, such as between ORMDL3 and RORA, where certain genotype combinations gave odds ratios for current asthma of 2.1 (95% CI 1.2-3.6 and 3.2 (95% CI 2.0-5.0 in the BAMSE and PARSIFAL children, respectively. Several combinations of environmental factors appeared to be important for the development of allergic disease in children. For example, use of baby formula and antibiotics early in life was associated with an odds ratio of 7.4 (95% CI 4.5-12.0 of developing asthma. Furthermore, genetic variants together with environmental factors seemed to play a role for allergic diseases, such as the use of antibiotics early in life and COL29A1 variants for asthma, and farm living and NPSR1 variants for allergic eczema. Overall, combinations of environmental and life style factors appeared more frequently in the models than combinations solely involving genes. In conclusion, a new bioinformatics approach is described for analyzing complex data, including extensive genetic and environmental information. Interactions identified with this approach could provide useful hints for further in-depth studies

  19. Rodent model of activity-based anorexia.

    Science.gov (United States)

    Carrera, Olaia; Fraga, Ángela; Pellón, Ricardo; Gutiérrez, Emilio

    2014-04-10

    Activity-based anorexia (ABA) consists of a procedure that involves the simultaneous exposure of animals to a restricted feeding schedule, while free access is allowed to an activity wheel. Under these conditions, animals show a progressive increase in wheel running, a reduced efficiency in food intake to compensate for their increased activity, and a severe progression of weight loss. Due to the parallelism with the clinical manifestations of anorexia nervosa including increased activity, reduced food intake and severe weight loss, the ABA procedure has been proposed as the best analog of human anorexia nervosa (AN). Thus, ABA research could both allow a better understanding of the mechanisms underlying AN and generate useful leads for treatment development in AN. Copyright © 2014 John Wiley & Sons, Inc.

  20. BASE 04 Transmission Loss Measurement and Modelling

    Science.gov (United States)

    2006-10-01

    réverbérations BREVER. Cet ajout avait pour but de permettre l’inversion des résultats de réverbérations établis à partir des données acoustiques ...données modélisées de séries temporelles de réverbérations basées sur une série de paramètres d’entrée décrivant les paramètres acoustiques d’une zone du...l’inversion des résultats de réverbérations établis à partir des données acoustiques enregistrées durant les essais BASE 04. Les essais effectués avec

  1. Adopsi Model Competency Based Training dalam Kewirausahaan

    Directory of Open Access Journals (Sweden)

    I Ketut Santra

    2009-01-01

    Full Text Available The aim of the research is improving the teaching method in entrepreneurship subject. This research adopted the competency based training (CBT into the entrepreneurship. The major task in this research is formulated and designed the entrepreneurship competency. Entrepreneurship competency indicated by Personal, Strategic and Situational and Business competence. All of entrepreneurship competences are described into sub topic of competence. After designing and formulating the game and simulation the research continuing to implement the competency based training in the real class. The time consumed to implementing the CBT one semester, starting on September 2006 to early February 2007. The lesson learnt from the implementation period, the CBT could improve the student competence in Personal, Situational Strategic and Business. The three of the competencies are important for the success entrepreneur. It is a sign of application of “Kurikulum Berbasis Kompetensi”. There are many evidences to describe the achievement of the CBT in entrepreneurship subject. Firstly, physically achievement, that all of the student’s business plan could became the real business. The evidences are presented by picture of the student’s real business. Secondly theoretically achievement, that the Personal, Situational Strategic and Business competence statistically have significant relation with Business Plan even Real Business quality. The effect of the Personal, Situational Strategic and Business competence to Business Plan quality is 84.4%. and, to the Real Business quality 77.2%. The statistic’s evidence suggests that the redesign of the entrepreneurship subject is the right way. The content of the entrepreneur competence (Personal, Situational and Strategic and Business competence have impact to the student to conduct and running for own business.

  2. Business model for sensor-based fall recognition systems.

    Science.gov (United States)

    Fachinger, Uwe; Schöpke, Birte

    2014-01-01

    AAL systems require, in addition to sophisticated and reliable technology, adequate business models for their launch and sustainable establishment. This paper presents the basic features of alternative business models for a sensor-based fall recognition system which was developed within the context of the "Lower Saxony Research Network Design of Environments for Ageing" (GAL). The models were developed parallel to the R&D process with successive adaptation and concretization. An overview of the basic features (i.e. nine partial models) of the business model is given and the mutual exclusive alternatives for each partial model are presented. The partial models are interconnected and the combinations of compatible alternatives lead to consistent alternative business models. However, in the current state, only initial concepts of alternative business models can be deduced. The next step will be to gather additional information to work out more detailed models.

  3. Saline as the sole contrast agent for successful MRI-guided epidural injections.

    Science.gov (United States)

    Deli, Martin; Fritz, Jan; Mateiescu, Serban; Busch, Martin; Carrino, John A; Becker, Jan; Garmer, Marietta; Grönemeyer, Dietrich

    2013-06-01

    To assess the performance of sterile saline solution as the sole contrast agent for percutaneous magnetic resonance imaging (MRI)-guided epidural injections at 1.5 T. A retrospective analysis of two different techniques of MRI-guided epidural injections was performed with either gadolinium-enhanced saline solution or sterile saline solution for documentation of the epidural location of the needle tip. T1-weighted spoiled gradient echo (FLASH) images or T2-weighted single-shot turbo spin echo (HASTE) images visualized the test injectants. Methods were compared by technical success rate, image quality, table time, and rate of complications. 105 MRI-guided epidural injections (12 of 105 with gadolinium-enhanced saline solution and 93 of 105 with sterile saline solution) were performed successfully and without complications. Visualization of sterile saline solution and gadolinium-enhanced saline solution was sufficient, good, or excellent in all 105 interventions. For either test injectant, quantitative image analysis demonstrated comparable high contrast-to-noise ratios of test injectants to adjacent body substances with reliable statistical significance levels (p < 0.001). The mean table time was 22 ± 9 min in the gadolinium-enhanced saline solution group and 22 ± 8 min in the saline solution group (p = 0.75). Sterile saline is suitable as the sole contrast agent for successful and safe percutaneous MRI-guided epidural drug delivery at 1.5 T.

  4. Saline as the Sole Contrast Agent for Successful MRI-guided Epidural Injections

    Energy Technology Data Exchange (ETDEWEB)

    Deli, Martin, E-mail: martin.deli@web.de [University of Witten/Herdecke, Department of Radiology and Microtherapy, Groenemeyer Institute for Microtherapy (GIMT) (Germany); Fritz, Jan, E-mail: jfritz9@jhmi.edu [Johns Hopkins University School of Medicine, Russell H. Morgan Department of Radiology and Radiological Science (United States); Mateiescu, Serban, E-mail: mateiescu@microtherapy.de; Busch, Martin, E-mail: busch@microtherapy.de [University of Witten/Herdecke, Department of Radiology and Microtherapy, Groenemeyer Institute for Microtherapy (GIMT) (Germany); Carrino, John A., E-mail: jcarrin2@jhmi.edu [Johns Hopkins University School of Medicine, Russell H. Morgan Department of Radiology and Radiological Science (United States); Becker, Jan, E-mail: j.becker@microtherapy.de; Garmer, Marietta, E-mail: garmer@microtherapy.de; Groenemeyer, Dietrich, E-mail: dg@microtherapy.de [University of Witten/Herdecke, Department of Radiology and Microtherapy, Groenemeyer Institute for Microtherapy (GIMT) (Germany)

    2013-06-15

    Purpose. To assess the performance of sterile saline solution as the sole contrast agent for percutaneous magnetic resonance imaging (MRI)-guided epidural injections at 1.5 T. Methods. A retrospective analysis of two different techniques of MRI-guided epidural injections was performed with either gadolinium-enhanced saline solution or sterile saline solution for documentation of the epidural location of the needle tip. T1-weighted spoiled gradient echo (FLASH) images or T2-weighted single-shot turbo spin echo (HASTE) images visualized the test injectants. Methods were compared by technical success rate, image quality, table time, and rate of complications. Results. 105 MRI-guided epidural injections (12 of 105 with gadolinium-enhanced saline solution and 93 of 105 with sterile saline solution) were performed successfully and without complications. Visualization of sterile saline solution and gadolinium-enhanced saline solution was sufficient, good, or excellent in all 105 interventions. For either test injectant, quantitative image analysis demonstrated comparable high contrast-to-noise ratios of test injectants to adjacent body substances with reliable statistical significance levels (p < 0.001). The mean table time was 22 {+-} 9 min in the gadolinium-enhanced saline solution group and 22 {+-} 8 min in the saline solution group (p = 0.75). Conclusion. Sterile saline is suitable as the sole contrast agent for successful and safe percutaneous MRI-guided epidural drug delivery at 1.5 T.

  5. Phytochromes are the sole photoreceptors for perceiving red/far-red light in rice.

    Science.gov (United States)

    Takano, Makoto; Inagaki, Noritoshi; Xie, Xianzhi; Kiyota, Seiichiro; Baba-Kasai, Akiko; Tanabata, Takanari; Shinomura, Tomoko

    2009-08-25

    Phytochromes are believed to be solely responsible for red and far-red light perception, but this has never been definitively tested. To directly address this hypothesis, a phytochrome triple mutant (phyAphyBphyC) was generated in rice (Oryza sativa L. cv. Nipponbare) and its responses to red and far-red light were monitored. Since rice only has three phytochrome genes (PHYA, PHYB and PHYC), this mutant is completely lacking any phytochrome. Rice seedlings grown in the dark develop long coleoptiles while undergoing regular circumnutation. The phytochrome triple mutants also show this characteristic skotomorphogenesis, even under continuous red or far-red light. The morphology of the triple mutant seedlings grown under red or far-red light appears completely the same as etiolated seedlings, and they show no expression of the light-induced genes. This is direct evidence demonstrating that phytochromes are the sole photoreceptors for perceiving red and far-red light, at least during rice seedling establishment. Furthermore, the shape of the triple mutant plants was dramatically altered. Most remarkably, triple mutants extend their internodes even during the vegetative growth stage, which is a time during which wild-type rice plants never elongate their internodes. The triple mutants also flowered very early under long day conditions and set very few seeds due to incomplete male sterility. These data indicate that phytochromes play an important role in maximizing photosynthetic abilities during the vegetative growth stage in rice.

  6. Root mucilage from pea and its utilization by rhizosphere bacteria as a sole carbon source.

    Science.gov (United States)

    Knee, E M; Gong, F C; Gao, M; Teplitski, M; Jones, A R; Foxworthy, A; Mort, A J; Bauer, W D

    2001-06-01

    Plant roots secrete a complex polysaccharide mucilage that may provide a significant source of carbon for microbes that colonize the rhizosphere. High molecular weight mucilage was separated by high-pressure liquid chromatography gel filtration from low molecular weight components of pea root exudate. Purified pea root mucilage generally was similar in sugar and glycosidic linkage composition to mucilage from cowpea, wheat, rice, and maize, but appeared to contain an unusually high amount of material that was similar to arabinogalactan protein. Purified pea mucilage was used as the sole carbon source for growth of several pea rhizosphere bacteria, including Rhizobium leguminosarum 8401 and 4292, Burkholderia cepacia AMMD, and Pseudomonas fluorescens PRA25. These species grew on mucilage to cell densities of three- to 25-fold higher than controls with no added carbon source, with cell densities of 1 to 15% of those obtained on an equal weight of glucose. Micromolar concentrations of nod gene-inducing flavonoids specifically stimulated mucilage-dependent growth of R. leguminosarum 8401 to levels almost equaling the glucose controls. R. leguminosarum 8401 was able to hydrolyze p-nitrophenyl glycosides of various sugars and partially utilize a number of purified plant polysaccharides as sole carbon sources, indicating that R. leguminosarum 8401 can make an unexpected variety of carbohydrases, in accordance with its ability to extensively utilize pea root mucilage.

  7. Saline as the Sole Contrast Agent for Successful MRI-guided Epidural Injections

    International Nuclear Information System (INIS)

    Deli, Martin; Fritz, Jan; Mateiescu, Serban; Busch, Martin; Carrino, John A.; Becker, Jan; Garmer, Marietta; Grönemeyer, Dietrich

    2013-01-01

    Purpose. To assess the performance of sterile saline solution as the sole contrast agent for percutaneous magnetic resonance imaging (MRI)-guided epidural injections at 1.5 T. Methods. A retrospective analysis of two different techniques of MRI-guided epidural injections was performed with either gadolinium-enhanced saline solution or sterile saline solution for documentation of the epidural location of the needle tip. T1-weighted spoiled gradient echo (FLASH) images or T2-weighted single-shot turbo spin echo (HASTE) images visualized the test injectants. Methods were compared by technical success rate, image quality, table time, and rate of complications. Results. 105 MRI-guided epidural injections (12 of 105 with gadolinium-enhanced saline solution and 93 of 105 with sterile saline solution) were performed successfully and without complications. Visualization of sterile saline solution and gadolinium-enhanced saline solution was sufficient, good, or excellent in all 105 interventions. For either test injectant, quantitative image analysis demonstrated comparable high contrast-to-noise ratios of test injectants to adjacent body substances with reliable statistical significance levels (p < 0.001). The mean table time was 22 ± 9 min in the gadolinium-enhanced saline solution group and 22 ± 8 min in the saline solution group (p = 0.75). Conclusion. Sterile saline is suitable as the sole contrast agent for successful and safe percutaneous MRI-guided epidural drug delivery at 1.5 T.

  8. Analysis of SSRs derived from an EST library of half-smooth tongue sole Cynoglossus semilaevis

    Science.gov (United States)

    Liu, Yunguo; Bao, Baolong; Chen, Songlin; Sun, Xiuqin

    2008-08-01

    A complementary DNA (cDNA) library was constructed from half-smooth tongue sole spleen. A long-read expressed sequence tag (EST) database was generated, containing 3100 cDNA clones, of which 220 clones were fully sequenced. A total of 1060 non-redundant simple sequence repeats (SSRs) were obtained from the cDNA library. An average of 5 kb sequence generates 1 SSR in the half-smooth tongue sole spleen cDNA library. The proportion of the SSR unit size was different in the cDNA library. The monomeric repeats (51.4%) are the most abundant class of SSR in the dataset. The dimeric, trimeric, tetrameric and hexameric repeats are represented in decreasing proportions of 27.2%, 16.0%, 2.8% and 1.9%, respectively. The frequency of pentameric repeats was observed the least (only 0.7%). Most of the monomeric and dimeric repeats are distributed in 3' and 5' un-translation region. If translation regions are considered merely, trimeric repeats are the highest, accounting for 57% of the total microsatellites.

  9. In defence of Kant's moral prohibition on suicide solely to avoid suffering.

    Science.gov (United States)

    Vong, G

    2008-09-01

    In Ian Brassington's article in a previous issue of this journal, he argues that suicide for the purpose of avoiding suffering is not, as Kant has contended, contrary to the moral law. Brassington's objections are not cogent because they rely upon the exegetically incorrect premise that according to Kant the priceless value of personhood is in the noumenal world that we have no perception of. On the basis of Kant's normative, metaphysical and epistemological theory, I argue, contrary to Brassington, that according to Kant personhood's moral value is explicitly in the sensible, phenomenal realm. While I argue that suicide solely to avoid suffering is immoral, I show that Kant's normative system allows some acts of suicide to be morally permissible. In the course of the discussion of the value of humanity's rationality and the immorality of suicide, I will discuss the broader modern medical ethical implications of Kant's arguments, such as the moral impermissibility of using rationality depriving drugs, such as ketamine, solely to avoid pain.

  10. Vibrio tapetis isolated from vesicular skin lesions in Dover sole Solea solea.

    Science.gov (United States)

    Declercq, A M; Chiers, K; Soetaert, M; Lasa, A; Romalde, J L; Polet, H; Haesebrouck, F; Decostere, A

    2015-06-29

    Vibrio tapetis is primarily known as the causative agent for brown ring disease in bivalves, although it has been isolated from cultivated fish during mortalities on farms. Here we describe the first isolation of V. tapetis from wild-caught and subsequently captive-held Dover sole Solea solea. Pathological features consisted of multifocal circular greyish-white skin discolourations evolving into vesicular lesions and subsequent ulcerations on the pigmented side. On the non-pigmented side, multiple circular lesions-white at the center and red at the edges-were evident. Histological examination of the vesicular lesions revealed dermal fluid-filled spaces, collagen tissue necrosis and a mixed inflammatory infiltrate, with large numbers of small rod-shaped bacteria. In the deep skin lesions, loss of scales and dermal connective tissue, with degeneration and fragmentation of the myofibres bordering the ulceration, were noted. Serotyping, DNA-DNA hybridization and REP- and ERIC-PCR techniques showed that the retrieved isolates displayed a profile similar to the representative strain of genotype/serotype O2 which originally was isolated from carpet-shell clam Venerupis decussata and to which isolates obtained from wedge sole Dicologoglossa cuneata were also closely related.

  11. A Model of FPGA-based Direct Torque Controller

    OpenAIRE

    Auzani Jidin; Aiman Zakwan Jidin; Nik Rumzi Nik Idris; Tole Sutikno

    2013-01-01

    This paper presents a generic model of a fully FPGA-based direct torque controller. This model is developed using two’s-complement fixed-point format approaches, in register-transfer-level (RTL) VHDL abstraction for minimizing calculation errors and consuming hardware resource usage. Therefore, the model is universal and can be implemented for all FPGA types. The model is prepared for fast computation, without using of CORDIC algorithm, a soft-core CPU, a transformation from Cartesian-to-pola...

  12. Inquiry based learning as didactic model in distant learning

    OpenAIRE

    Rothkrantz, L.J.M.

    2015-01-01

    Recent years many universities are involved in development of Massive Open Online Courses (MOOCs). Unfortunately an appropriate didactic model for cooperated network learning is lacking. In this paper we introduce inquiry based learning as didactic model. Students are assumed to ask themselves questions interacting with a learning text. The model has been tested for students of DUT taking a MOOC in mathematics. The didactic model and test results are presented.

  13. Effectiveness of rocker sole shoes in the management of chronic low back pain: a randomized clinical trial.

    Science.gov (United States)

    MacRae, Catharine Siân; Lewis, Jeremy S; Shortland, Adam P; Morrissey, Matthew C; Critchley, Duncan

    2013-10-15

    Multicenter, assessor-blind, randomized, clinical trial. To compare the effectiveness of rocker sole footwear to traditional flat sole footwear as part of the management for people with low back pain (LBP). During the past decade, persistent advertising has claimed that footwear constructed with a rocker sole will reduce LBP. However, there is no robust evidence to support these claims. One hundred fifteen people with chronic LBP were randomized to wear rocker sole shoes or flat sole shoes for a minimum of 2 hours each day while standing and walking. Primary outcome was the Roland Morris Disability Questionnaire (RMDQ). In addition, participants attended an exercise and education program once a week for 4 weeks and wore their assigned shoes during these sessions. Participants were assessed without their knowledge of group allocation prerandomization, and at 6 weeks, 6 months, and 1 year (main outcome point). Analysis was by intention-to-treat method. At 12 months, data from 44 of 58 (77.2%) of the rocker sole group and 49 of 57 (84.5%) of the flat sole group were available for analysis. In the rocker sole group, mean reduction in RMDQ was -3.1 (95% CI [confidence interval], -4.5 to -1.6), and in the flat sole group, it was -4.4 (95% CI, -5.8 to -3.1) (a greater negative value represents a greater reduction in disability). At 6 months, more people wearing flat shoes compared with those wearing rocker shoes demonstrated a minimal clinically important improvement in disability (53.2% and 31.1%, respectively; P = 0.03). Between-group differences were not significant for RMDQ or any secondary outcomes (e.g., pain) at any time. People reporting pain when standing and walking at baseline (n = 59) reported a greater reduction in RMDQ at 12 months in the flat sole group (-4.4 [95% CI, -6.0 to -2.8], n = 29) than the rocker sole group (-2.0 [95% CI, -3.6 to -0.4], n = 30) (P shoes seem to be no more beneficial than flat sole shoes in affecting disability and pain outcomes in

  14. Intelligent Transportation and Evacuation Planning A Modeling-Based Approach

    CERN Document Server

    Naser, Arab

    2012-01-01

    Intelligent Transportation and Evacuation Planning: A Modeling-Based Approach provides a new paradigm for evacuation planning strategies and techniques. Recently, evacuation planning and modeling have increasingly attracted interest among researchers as well as government officials. This interest stems from the recent catastrophic hurricanes and weather-related events that occurred in the southeastern United States (Hurricane Katrina and Rita). The evacuation methods that were in place before and during the hurricanes did not work well and resulted in thousands of deaths. This book offers insights into the methods and techniques that allow for implementing mathematical-based, simulation-based, and integrated optimization and simulation-based engineering approaches for evacuation planning. This book also: Comprehensively discusses the application of mathematical models for evacuation and intelligent transportation modeling Covers advanced methodologies in evacuation modeling and planning Discusses principles a...

  15. SDG and qualitative trend based model multiple scale validation

    Science.gov (United States)

    Gao, Dong; Xu, Xin; Yin, Jianjin; Zhang, Hongyu; Zhang, Beike

    2017-09-01

    Verification, Validation and Accreditation (VV&A) is key technology of simulation and modelling. For the traditional model validation methods, the completeness is weak; it is carried out in one scale; it depends on human experience. The SDG (Signed Directed Graph) and qualitative trend based multiple scale validation is proposed. First the SDG model is built and qualitative trends are added to the model. And then complete testing scenarios are produced by positive inference. The multiple scale validation is carried out by comparing the testing scenarios with outputs of simulation model in different scales. Finally, the effectiveness is proved by carrying out validation for a reactor model.

  16. Evaluating Emulation-based Models of Distributed Computing Systems

    Energy Technology Data Exchange (ETDEWEB)

    Jones, Stephen T. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Cyber Initiatives; Gabert, Kasimir G. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Cyber Initiatives; Tarman, Thomas D. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Emulytics Initiatives

    2017-08-01

    Emulation-based models of distributed computing systems are collections of virtual ma- chines, virtual networks, and other emulation components configured to stand in for oper- ational systems when performing experimental science, training, analysis of design alterna- tives, test and evaluation, or idea generation. As with any tool, we should carefully evaluate whether our uses of emulation-based models are appropriate and justified. Otherwise, we run the risk of using a model incorrectly and creating meaningless results. The variety of uses of emulation-based models each have their own goals and deserve thoughtful evaluation. In this paper, we enumerate some of these uses and describe approaches that one can take to build an evidence-based case that a use of an emulation-based model is credible. Predictive uses of emulation-based models, where we expect a model to tell us something true about the real world, set the bar especially high and the principal evaluation method, called validation , is comensurately rigorous. We spend the majority of our time describing and demonstrating the validation of a simple predictive model using a well-established methodology inherited from decades of development in the compuational science and engineering community.

  17. Agent-based model of soil water dynamics

    Science.gov (United States)

    Mewes, Benjamin; Schumann, Andreas

    2017-04-01

    In the last decade, agent based modelling became more and more popular in social science, biology and environmental modelling. The concept is designed to simulate systems that are highly dynamic and sensitive to small variations in their composition and their state. As hydrological systems often show dynamic and nonlinear behaviour, agent based modelling can be an adequate way to model aquatic systems. Nevertheless, up to now only a few results on agent based modelling are known in hydrology. Processes like the percolation of water through the soil are highly responsive to the state of the pedological system. To simulate these water fluxes correctly by known approaches like the Green-Ampt model or approximations to the Richards equation, small time steps and a high spatial discretisation are needed. In this study a new approach for modelling water fluxes in a soil column is presented: autonomous water agents that transport water through the soil while interacting with their environment as well as with other agents under physical laws. Setting up an agent-based model requires a predefined rule set for the behaviour of the autonomous agents. Moreover, we present some principle assumptions of the interaction not only between agents, but as well between agents and their environment. Our study shows that agent-based modelling in hydrology leads to very promising results but we also have to face new challenges.

  18. Model Based Mission Assurance: Emerging Opportunities for Robotic Systems

    Science.gov (United States)

    Evans, John W.; DiVenti, Tony

    2016-01-01

    The emergence of Model Based Systems Engineering (MBSE) in a Model Based Engineering framework has created new opportunities to improve effectiveness and efficiencies across the assurance functions. The MBSE environment supports not only system architecture development, but provides for support of Systems Safety, Reliability and Risk Analysis concurrently in the same framework. Linking to detailed design will further improve assurance capabilities to support failures avoidance and mitigation in flight systems. This also is leading new assurance functions including model assurance and management of uncertainty in the modeling environment. Further, the assurance cases, a structured hierarchal argument or model, are emerging as a basis for supporting a comprehensive viewpoint in which to support Model Based Mission Assurance (MBMA).

  19. Modeling and knowledge acquisition processes using case-based inference

    Directory of Open Access Journals (Sweden)

    Ameneh Khadivar

    2017-03-01

    Full Text Available The method of acquisition and presentation of the organizational Process Knowledge has considered by many KM researches. In this research a model for process knowledge acquisition and presentation has been presented by using the approach of Case Base Reasoning. The validation of the presented model was evaluated by conducting an expert panel. Then a software has been developed based on the presented model and implemented in Eghtesad Novin Bank of Iran. In this company, based on the stages of the presented model, first the knowledge intensive processes has been identified, then the Process Knowledge was stored in a knowledge base in the format of problem/solution/consequent .The retrieval of the knowledge was done based on the similarity of the nearest neighbor algorithm. For validating of the implemented system, results of the system has compared by the results of the decision making of the expert of the process.

  20. Learning-based Nonlinear Model Predictive Control to Improve Vision-based Mobile Robot Path Tracking

    Science.gov (United States)

    2015-07-01

    Traditional path- tracking controllers would represent the robot using a bicycle model (Figure 8) with steering angle, δcmd,k, and linear velocity...Learning-based Nonlinear Model Predictive Control to Improve Vision-based Mobile Robot Path Tracking Chris J. Ostafew Institute for Aerospace Studies...paper presents a Learning-based Nonlinear Model Predictive Control (LB-NMPC) algorithm to achieve high-performance path tracking in challenging off-road