WorldWideScience

Sample records for models based solely

  1. A Simple Model for Estimating Evapotranspiration Based Solely on Remote Sensing: Algorithm and Application

    Science.gov (United States)

    Sun, Z.; Wang, Q.; Matsushita, B.; Fukushima, T.; Ouyang, Z.; Gebremichael, M.

    2009-12-01

    Remote sensing (RS) has been considered as the most promising tool for evapotranspiration (ET) estimations from local, regional to global scales. Many studies have been conducted to estimated ET using RS data, however, most of them are based partially on ground observations. This limits the applications of these algorithms when the necessary data are unavailable. Some other algorithms can generate real-time ET solely using remote sensing data, but lack mechanistic realism. In our study, we developed a new dual-source Simple Remote Sensing EvapoTranspiration model (Sim-ReSET) based only on RS data. One merit of this model is that the calculation of aerodynamic resistance can be avoided by means of a reference dry bare soil and an assumption that wind speed at the upper boundary of atmospheric surface layer is homogenous, but the aerodynamic characters are still considered by means of canopy height. The other merit is that all inputs (net radiation, soil heat flux, canopy height, variables related to land surface temperature) can be potentially obtained from remote sensing data, which allows obtaining regular RS-driven ET product. For the purposes of sensitivity analysis and performance evaluation of the Sim-ReSET model without the effect of potential uncertainties and errors from remote sensing data, the Sim-ReSET model was tested only using intensive ground observations at the Yucheng ecological station in the North China Plain from 2006 to 2008. Results show that the model has a good performance for instantaneous ET estimations with a mean absolute difference (MAD) of 34.27 W/m2 and a root mean square error (RMSE) of 41.84 W/m2 under neutral or near-neutral atmospheric conditions. On 12 cloudless days, the MAD of daily ET accumulated from instantaneous estimations is 0.26 mm/day, and the RMSE is 0.30 mm/day. In our study, we mapped Asian 16-day ET from 2000 to 2009 only using MODIS land data products based on the Sim-ReSET model. Then, the obtained ET product was

  2. Modelling larval dispersal dynamics of common sole (Solea solea) along the western Iberian coast

    Science.gov (United States)

    Tanner, Susanne E.; Teles-Machado, Ana; Martinho, Filipe; Peliz, Álvaro; Cabral, Henrique N.

    2017-08-01

    Individual-based coupled physical-biological models have become the standard tool for studying ichthyoplankton dynamics and assessing fish recruitment. Here, common sole (Solea solea L.), a flatfish of high commercial importance in Europe was used to evaluate transport of eggs and larvae and investigate the connectivity between spawning and nursery areas along the western Iberian coast as spatio-temporal variability in dispersal and recruitment patterns can result in very strong or weak year-classes causing large fluctuations in stock size. A three-dimensional particle tracking model coupled to Regional Ocean Modelling System model was used to investigate variability of sole larvae dispersal along the western Iberian coast over a five-year period (2004-2009). A sensitivity analysis evaluating: (1) the importance of diel vertical migrations of larvae and (2) the size of designated recruitment areas was performed. Results suggested that connectivity patterns of sole larvae dispersal and their spatio-temporal variability are influenced by the configuration of the coast with its topographical structures and thus the suitable recruitment area available as well as the wind-driven mesoscale circulation along the Iberian coast.

  3. Discriminating bot accounts based solely on temporal features of microblog behavior

    Science.gov (United States)

    Pan, Junshan; Liu, Ying; Liu, Xiang; Hu, Hanping

    2016-05-01

    As the largest microblog service in China, Sina Weibo has attracted numerous automated applications (known as bots) due to its popularity and open architecture. We classify the active users from Sina Weibo into human, bot-based and hybrid groups based solely on the study of temporal features of their posting behavior. The anomalous burstiness parameter and time-interval entropy value are exploited to characterize automation. We also reveal different behavior patterns among the three types of users regarding their reposting ratio, daily rhythm and active days. Our findings may help Sina Weibo manage a better community and should be considered for dynamic models of microblog behaviors.

  4. Modelling growth and bioaccumulation of Polychlorinated biphenyls in common sole ( Solea solea)

    Science.gov (United States)

    Eichinger, M.; Loizeau, V.; Roupsard, F.; Le Guellec, A. M.; Bacher, C.

    2010-10-01

    Experiments were performed on juvenile sole in controlled conditions in the aim of understanding how the biology of common sole may affect the accumulation and dilution of Polychlorinated biphenyls (PCBs). The fish were raised in optimal conditions and divided into two tanks: one control tank and one PCB tank. 4 PCB congeners were added to food for 3 months in the PCB tank; the soles were subsequently fed unspiked food for 3 months. Growth (length and weight) and PCB concentrations were monitored in both tanks and juvenile sole growth was not significantly affected by PCBs in our experimental conditions. We used the Dynamic Energy Budget (DEB) theory to model sole biology and paid special attention to model calibration through the wide use of data from the literature. The model accurately reproduced fish growth in both tanks. We coupled a bioaccumulation model to reproduce the concentration dynamics of the 4 PCB congeners used. This model did not require additional calibration and was dependent solely on the growth model and PCB concentrations in food. The bioaccumulation model accurately simulated PCB accumulation in fish, but overestimated PCB concentrations in fish during the dilution phase. This may suggest that in addition to PCB dilution due to growth, PCB concentrations decreased due to other PCB elimination mechanisms. Finally, we discussed potential improvements to the model and its future applications.

  5. Robust design in generelaised linear models for improving the quality of polyurethane soles

    Directory of Open Access Journals (Sweden)

    Castro, Armando Mares

    2015-11-01

    Full Text Available In a process that manufactures polyurethane soles by casting, a number of problems lead to different types of defects on the sole, causing significant economic losses for the company. In order to improve the product quality and decrease the number of defects, this study conducts an experimental design in the context of robust design. Since the response variable is binary, the statistical analysis was performed using generalised linear models. The operational methodology reduced the percentage of defects, while combining the experimental technique and control systems to achieve superior quality and a consequent reduction in costs.

  6. The individual tolerance concept is not the sole explanation for the probit dose-effect model

    Energy Technology Data Exchange (ETDEWEB)

    Newman, M.C.; McCloskey, J.T.

    2000-02-01

    Predominant methods for analyzing dose- or concentration-effect data (i.e., probit analysis) are based on the concept of individual tolerance or individual effective dose (IED, the smallest characteristic dose needed to kill an individual). An alternative explanation (stochasticity hypothesis) is that individuals do not have unique tolerances: death results from stochastic processes occurring similarly in all individuals. These opposing hypotheses were tested with two types of experiments. First, time to stupefaction (TTS) was measured for zebra fish (Brachydanio rerio) exposed to benzocaine. The same 40 fish were exposed during five trials to test if the same order for TTS was maintained among trials. The IED hypothesis was supported with a minor stochastic component being present. Second, eastern mosquitofish (Gambusia holbrooki) were exposed to sublethal or lethal NaCl concentrations until a large portion of the lethally exposed fish died. After sufficient time for recovery, fish sublethally exposed and fish surviving lethal exposure were exposed simultaneously to lethal NaCl concentrations. No statistically significant effect was found of previous exposure on survival time but a large stochastic component to the survival dynamics was obvious. Repetition of this second type of test with pentachlorophenol also provided no support for the IED hypothesis. The authors conclude that neither hypothesis alone was the sole or dominant explanation for the lognormal (probit) model. Determination of the correct explanation (IED or stochastic) or the relative contributions of each is crucial to predicting consequences to populations after repeated or chronic exposures to any particular toxicant.

  7. Construction of a microsatellite-based genetic linkage map for half-smooth tongue sole Cynoglossus semilaevis

    Institute of Scientific and Technical Information of China (English)

    Wentao SONG; Guidong MIAO; Yongwei ZHAO; Yuze NIU; Renyi PANG; Xiaolin LIAO; Changwei SHAO

    2013-01-01

    The half-smooth tongue sole Cynoglossus semilaevis is an important cultured marine fish and a promising model fish for the study of sex determination.Sex-specific genetic linkage maps of half-smooth tongue sole were developed with 567 markers (565 microsatellite markers and two SCAR markers).The parents and F1 progeny (92 individuals) were used as segregating populations.The female map was composed of 480 markers in 21 linkage groups,covering a total of 1388.1 cM,with an average interval 3.06 cM between markers.The male map consisted of 417 markers in 21 linkage groups,spanning 1480.9 cM,with an average interval of 3.75 cM.The female and male maps had 474 and 416 unique positions,respectively.The genome length of half-smooth tongue sole was estimated to be 1522.9 cM for females and 1649.1cM for males.Based on estimations of map length,the female and male maps covered 91.1% and 89.8% of the genome,respectively.Furthermore,two female-specific SCAR markers,f-382 and f-783,were mapped on LG15f (linkage group 15 in female maps).The present study presents a mid-density genetic linkage map for half-smooth tongue sole.These improved genetic linkage maps may facilitate systematic genome searches to identify quantitative trait loci (QTL),such as disease resistance,growth and sex-related traits,and are very useful for marker-assisted selection breeding programs for economically important traits in half-smooth tongue sole [Current Zoology 59 (1):31-52,2013].

  8. Toward developing recombinant gonadotropin-based hormone therapies for increasing fertility in the flatfish Senegalese sole

    Science.gov (United States)

    Chauvigné, François; Ollé, Judith; González, Wendy; Duncan, Neil; Giménez, Ignacio

    2017-01-01

    Captive flatfishes, such as the Senegalese sole, typically produce very low volumes of sperm. This situation is particularly prevalent in the first generation (F1) of reared sole males, which limits the development of artificial fertilization methods and the implementation of selective breeding programs. In this study, we investigated whether combined treatments with homologous recombinant follicle-stimulating (rFsh) and luteinizing (rLh) hormones, produced in a mammalian host system, could stimulate spermatogenesis and enhance sperm production in Senegalese sole F1 males. In an initial autumn/winter experiment, weekly intramuscular injections with increasing doses of rFsh over 9 weeks resulted in the stimulation of gonad weight, androgen release, germ cell proliferation and entry into meiosis, and the expression of different spermatogenesis-related genes, whereas a subsequent single rLh injection potentiated spermatozoa differentiation. In a second late winter/spring trial corresponding to the sole’s natural prespawning and spawning periods, we tested the effect of repeated rLh injections on the amount and quality of sperm produced by males previously treated with rFsh for 4, 6, 8 or 10 weeks. These latter results showed that the combination of rFsh and rLh treatments could increase sperm production up to 7 times, and slightly improve the motility of the spermatozoa, although a high variability in the response was found. However, sustained administration of rFsh during spawning markedly diminished Leydig cell survival and the steroidogenic potential of the testis. These data suggest that in vivo application of rFsh and rLh is effective at stimulating spermatogenesis and sperm production in Senegalese sole F1 males, setting the basis for the future establishment of recombinant gonadotropin-based hormone therapies to ameliorate reproductive dysfunctions of this species. PMID:28329024

  9. Habitat suitability for juvenile common sole ( Solea solea, L.) in the Bay of Biscay (France): A quantitative description using indicators based on epibenthic fauna

    Science.gov (United States)

    Le Pape, Olivier; Baulier, Loîc; Cloarec, Aurélie; Martin, Jocelyne; Le Loc'h, François; Désaunay, Yves

    2007-02-01

    This study describes the spatial distribution of young-of-the-year common sole based on beam trawl surveys conducted in late summer in the coastal and estuarine parts of the Bay of Biscay (France). Previous studies showed that habitat suitability for juvenile common sole varies according to physical factors and notably bathymetry and sediment structure. Nevertheless, the use of these descriptors alone to model habitat suitability led to considerable unexplained variability in juvenile common sole distribution. Hence, the epibenthic macro- and megafauna collected during beam trawl surveys was taken into account to improve models of habitat suitability for these juvenile flatfish. Ecotrophic guilds based on life traits (behaviour, mobility and feeding) were used to develop generic indicators of trawled benthic fauna. These synthetic descriptors were used in generalized linear models of habitat suitability in order to characterize the distribution of juvenile common sole. This approach significantly improved the description based on physical descriptors and allowed demonstrating that young common sole distribution is related to the density of trawled deposit and suspension feeders and also of carnivorous organisms. These models provide a reliable method to develop indicators of nursery habitat suitability from trawl survey data with the aim of assessing and surveying their quality.

  10. Effects of de-oiled palm kernel cake based fertilizers on sole maize ...

    African Journals Online (AJOL)

    AJL

    2012-03-08

    Mar 8, 2012 ... formulations on the yield of sole maize and cassava crops. Two de-oiled palm ... cake, urea, muriate of potash and single super phosphate. Two separate ..... establishment of nitrogen fixing bacteria in the rhizosphere. Microb.

  11. Old Soles

    Institute of Scientific and Technical Information of China (English)

    Yu Yan

    2012-01-01

    Amid the rhythmic tap-dance of production inside Neiliansheng's factory in Xicheng District of Beijing,He Kaiying,a master of Neiliansheng cloth shoes,was teaching an apprentice to draw the outline of a sole.The 56-year-old senior shoemaker guides three young apprentices,passing on traditional shoemaking skills that have been in place since the company's establishment. Neiliansheng,which means "unstopped promotions in official ranks" in Chinese,is a classic cloth shoe brand created in Beijing in 1853.It once provided shoes for emperors and royal court officials.At that time,wearing the court shoes of Neiliansheng was a fashion statement in Beijing and a mark of high status.

  12. Sensory bases and the mode of feeding behavior of tongue sole Cynoglossus semilaevis

    Institute of Scientific and Technical Information of China (English)

    WANG Xinan; MA Aijun

    2009-01-01

    We conducted behavior experiments on the roles of vision, olfaction, and the lateral line in feeding in tongue sole Cynoglossus semilaevis Günter. Chemical cues from the prey alone could not elicit any searching or attacking behavior by the fish; only when moving foods were presented, the chemical nature of the foods affected feeding. In addition, we found that normal tongue sole did not accurately recognize moving artificial prey of different shapes. Neither chemosense nor vision plays an important role in prey detection. Reactions to moving objects and the response of the oropharyngeal cavity to different foods showed that the (eyeless) tongue sole use mainly the lateral line for prey detection and capture. Gustation in the oropharyngeal cavity is essential for the fish to swallow its prey.

  13. Quality of coastal and estuarine essential fish habitats: estimations based on the size of juvenile common sole ( Solea solea L.)

    Science.gov (United States)

    Le Pape, O.; Holley, J.; Guérault, D.; Désaunay, Y.

    2003-12-01

    Survival and growth of early fish stages are maximal in coastal and estuarine habitats where natural shallow areas serve as nurseries for a variety of widely distributed species on the continental shelf. Processes occurring in these nursery grounds during the juvenile stage affect growth and may be important in regulating the year-class strength of fishes and population size. The need, therefore, exists to protect these essential fish habitats hence to develop indicators to estimate their quality. The purpose of the present study was to use the growth of juvenile sole as a means of comparing the quality of coastal and estuarine nursery habitats in the Bay of Biscay (France). These sole nurseries were clearly identified from studies based on trawl surveys carried out during the last two decades. The size of 1-group juveniles at the end of their second summer, as estimated from these surveys, is an indicator of growth in these habitats during the juvenile phase and can be used to compare habitat quality. A model taking into account the role of seawater temperature in spatial and interannual variations of juvenile size was developed to compare growth performance in the different nursery sectors. This study shows that the size of juvenile sole after two summers of life is not density-dependent, probably because the size of the population adapts to habitat capacity after high mortality during early-juvenile stages. Size is on one hand positively related to temperature and on the other hand higher in estuarine than in non-estuarine habitats. This high growth potential of juvenile fish in estuarine areas confirms the very important role played by estuaries as nursery grounds and the essential ecological interest of these limited areas in spite of their low water quality. If a general conclusion on habitat quality is to be reached about studies based on the growth of juvenile fish, it is necessary to use not only an integrative indicator of growth, like size

  14. Formation of a cold ophiolitic sole at the base of the Devonian Balkan Carpathian Ophiolite (Romania, Serbia, Bulgaria)

    Science.gov (United States)

    Plissart, Gaëlle; Diot, Hervé; Monnier, Christophe; Maruntiu, Marcel; Debaille, Vinciane; Neubauer, Franz

    2013-04-01

    Our study concerns deformed gabbroic rocks from the Balkan Carpathian Ophiolite (BCO - Romania, Serbia, Bulgaria). The BCO consists of four ophiolitic massifs dismembered during Alpine tectonic and displaying together a complete classical oceanic lithosphere. Our new Sm-Nd dating on fresh lower gabbroic rocks give an accretion age for the BCO crust at 409 ± 38 Ma, in agreement with a previous age of 405 ± 3 Ma (Zakariadze et al. 2012). After removing the Alpine tectonic, the BCO appears as an elongated E-W body tilted to the south. At the base of the ophiolitic complex occurs a thin deformed zone (data indicate that their protoliths were mainly upper gabbros statically metamorphosed in the Greenschist/Amphibolite facies (event 1 = ocean-floor metamorphism at the ridge axis). These rocks have been affected by a second circulation of fluids (event 2), contemporaneous to a deformation and inducing local K-enrichment (formation of Cr-muscovite). Temperature estimates for this event indicate a range of 450°C - 280°C, with the lower values observed for the more intensively metasomatized rocks. 40Ar - 39Ar dating on two Cr-muscovites from slightly and highly deformed metagabbros gives plateau ages of 372.6 ± 1.3 Ma and 360.6 ± 1.2 Ma respectively. We interpret the first age as a mimimum age for the beginning of the event 2, observed into preserved rocks, and the second one as linked to (neo-/)recrystallisation due to localisation of the metasomatism/deformation. The interval of 30 Ma between oceanic crust accretion and initiation of metasomatism/deformation involves that the upper oceanic crust had cooled down to temperatures close to 100°C before the beginning of event 2. Consequently, a temperature increase is required to observe the greenschist facies assemblage. We have tested by tectono-thermal modelling the hypothesis that these rocks could correspond to a slice of upper crust dragged down during intra-oceanic subduction: temperatures of 450°C are reached at

  15. A HUBBLE DIAGRAM FROM TYPE II SUPERNOVAE BASED SOLELY ON PHOTOMETRY: THE PHOTOMETRIC COLOR METHOD

    Energy Technology Data Exchange (ETDEWEB)

    De Jaeger, T.; González-Gaitán, S.; Galbany, L.; Hamuy, M.; Gutiérrez, C. P.; Kuncarayakti, H. [Millennium Institute of Astrophysics, Santiago (Chile); Anderson, J. P. [European Southern Observatory, Alonso de Córdova 3107, Casilla 19, Santiago (Chile); Phillips, M. M.; Campillay, A.; Castellón, S.; Hsiao, E. Y.; Morrell, N. [Las Campanas Observatory, Carnegie Observatories, Casilla 601, La Serena (Chile); Stritzinger, M. D.; Contreras, C. [Department of Physics and Astronomy, Aarhus University, Ny Munkegade 120, DK-8000 Aarhus C (Denmark); Bolt, L. [Argelander Institut für Astronomie, Universität Bonn, Auf dem Hgel 71, D-53111 Bonn (Germany); Burns, C. R. [Observatories of the Carnegie Institution for Science, Pasadena, CA 91101 (United States); Folatelli, G. [Instituto de Astrofísica de La Plata, CONICET, Paseo del Bosque S/N, B1900FWA, La Plata (Argentina); Freedman, W. L. [Department of Astronomy and Astrophysics, University of Chicago, Chicago, IL 60637 (United States); Krisciunas, K. [George P. and Cynthia Woods Mitchell Institute for Fundamental Physics and Astronomy, Department of Physics and Astronomy, Texas A and M University, College Station, TX 77843 (United States); Krzeminski, W., E-mail: dthomas@das.uchile.cl [N. Copernicus Astronomical Center, ul. Bartycka 18, 00-716 Warszawa (Poland); and others

    2015-12-20

    We present a Hubble diagram of SNe II using corrected magnitudes derived only from photometry, with no input of spectral information. We use a data set from the Carnegie Supernovae Project I for which optical and near-infrared light curves were obtained. The apparent magnitude is corrected by two observables, one corresponding to the slope of the plateau in the V band and the second a color term. We obtain a dispersion of 0.44 mag using a combination of the (V − i) color and the r band and we are able to reduce the dispersion to 0.39 mag using our golden sample. A comparison of our photometric color method (PCM) with the standardized candle method (SCM) is also performed. The dispersion obtained for the SCM (which uses both photometric and spectroscopic information) is 0.29 mag, which compares with 0.43 mag from the PCM for the same SN sample. The construction of a photometric Hubble diagram is of high importance in the coming era of large photometric wide-field surveys, which will increase the detection rate of supernovae by orders of magnitude. Such numbers will prohibit spectroscopic follow up in the vast majority of cases, and hence methods must be deployed which can proceed using solely photometric data.

  16. Spawning period of Senegal sole, Solea senegalensis, based on juvenile otolith microstructure

    Science.gov (United States)

    Vinagre, Catarina; Maia, Anabela; Amara, Rachid; Cabral, Henrique N.

    2013-02-01

    The Senegal sole, Solea senegalensis, is a flatfish species distributed from the Bay of Biscay to the coast of South Africa. Although it is a species of high commercial value its spawning period remains poorly known. In the Tagus estuary, Portugal, two juvenile cohorts of this species colonize two independent nursery areas within the estuarine system. Left lapilli otoliths of these 0-group juveniles were used to estimate age and back-calculate hatch dates, thus allowing the estimation of S. senegalensis spawning period in the Portuguese coast. The two cohorts of S. senegalensis completed the colonization of the two nurseries in July. The ages of juveniles were estimated to range between 46 and 111 days in nursery A, and between 33 and 61 days in nursery B. Hatch dates ranged from April to early June for juveniles colonizing nursery A, and from May to early June for juveniles colonizing nursery B. The mean hatch date in nursery A was the 7th of May, while in nursery B it was the 25th of May. It was concluded that the spawning period for this species off the Portuguese coast was from April to June.

  17. Kinetic characterization of the sole nonmuscle myosin-2 from the model organism Drosophila melanogaster.

    Science.gov (United States)

    Heissler, Sarah M; Chinthalapudi, Krishna; Sellers, James R

    2015-04-01

    Nonmuscle myosin-2 is the primary enzyme complex powering contractility of the F-actin cytoskeleton in the model organism Drosophila. Despite myosin's essential function in fly development and homeostasis, its kinetic features remain elusive. The purpose of this in vitro study is a detailed steady-state and presteady-state kinetic characterization of the Drosophila nonmuscle myosin-2 motor domain. Kinetic features are a slow steady-state ATPase activity, high affinities for F-actin and ADP, and a low duty ratio. Comparative analysis of the overall enzymatic signatures across the nonmuscle myosin-2 complement from model organisms indicates that the Drosophila protein resembles nonmuscle myosin-2s from metazoa rather than protozoa, though modulatory aspects of myosin motor function are distinct. Drosophila nonmuscle myosin-2 is uniquely insensitive toward blebbistatin, a commonly used myosin-2 inhibitor. An in silico modeling approach together with kinetic studies indicate that the nonconsensus amino acid Met466 in the Drosophila nonmuscle myosin-2 active-site loop switch-2 acts as blebbistatin desensitizer. Introduction of the M466I mutation sensitized the protein for blebbistatin, resulting in a half-maximal inhibitory concentration of 36.3 ± 4.1 µM. Together, these data show that Drosophila nonmuscle myosin-2 is a bona fide molecular motor and establish an important link between switch-2 and blebbistatin sensitivity.

  18. EPA Sole Source Aquifers

    Data.gov (United States)

    U.S. Environmental Protection Agency — Information on sole source aquifers (SSAs) is widely used in assessments under the National Environmental Policy Act and at the state and local level. A national...

  19. Functional diversity of the microbial community in healthy subjects and periodontitis patients based on sole carbon source utilization.

    Directory of Open Access Journals (Sweden)

    Yifei Zhang

    Full Text Available Chronic periodontitis is one of the most common forms of biofilm-induced diseases. Most of the recent studies were focus on the dental plaque microbial diversity and microbiomes. However, analyzing bacterial diversity at the taxonomic level alone limits deeper comprehension of the ecological relevance of the community. In this study, we compared the metabolic functional diversity of the microbial community in healthy subjects and periodontitis patients in a creative way--to assess the sole carbon source utilization using Biolog assay, which was first applied on oral micro-ecology assessment. Pattern analyses of 95-sole carbon sources catabolism provide a community-level phenotypic profile of the microbial community from different habitats. We found that the microbial community in the periodontitis group had greater metabolic activity compared to the microbial community in the healthy group. Differences in the metabolism of specific carbohydrates (e.g. β-methyl-D-glucoside, stachyose, maltose, D-mannose, β-methyl-D-glucoside and pyruvic acid were observed between the healthy and periodontitis groups. Subjects from the healthy and periodontitis groups could be well distinguished by cluster and principle component analyses according to the utilization of discriminate carbon sources. Our results indicate significant difference in microbial functional diversity between healthy subjects and periodontitis patients. We also found Biolog technology is effective to further our understanding of community structure as a composite of functional abilities, and it enables the identification of ecologically relevant functional differences among oral microbial communities.

  20. SoleSound

    DEFF Research Database (Denmark)

    Zanotto, Damiano; Turchet, Luca; Boggs, Emily Marie;

    2014-01-01

    This paper introduces the design of SoleSound, a wearable system designed to deliver ecological, audio-tactile, underfoot feedback. The device, which primarily targets clinical applications, uses an audio-tactile footstep synthesis engine informed by the readings of pressure and inertial sensors...

  1. A second-generation total synthesis of (+)-discodermolide: the development of a practical route using solely substrate-based stereocontrol.

    Science.gov (United States)

    Paterson, Ian; Delgado, Oscar; Florence, Gordon J; Lyothier, Isabelle; O'Brien, Matthew; Scott, Jeremy P; Sereinig, Natascha

    2005-01-01

    A novel total synthesis of the complex polyketide (+)-discodermolide, a promising anticancer agent of sponge origin, has been completed in 7.8% overall yield over 24 linear steps, with 35 steps altogether. This second-generation approach was designed to rely solely on substrate control for introduction of the required stereochemistry, eliminating the use of all chiral reagents or auxiliaries. The common 1,2-anti-2,3-syn stereotriad found in each of three subunits, aldehyde 9 (C(1)-C(5)), ester 40 (C(9)-C(16)), and aldehyde 13 (C(17)-C(24)), was established via a boron-mediated aldol reaction of ethyl ketone 15 and formaldehyde, followed by hydroxyl-directed reduction to give 1,3-diol 14. Alternatively, a surrogate aldehyde 22 was employed for formaldehyde in this aldol reaction, leading to the beta-hydroxy aldehyde 20 as a common building block, corresponding to the discodermolide stereotriad. Key fragment unions were achieved by a lithium-mediated anti aldol reaction of ester 40 and aldehyde 13 under Felkin-Anh control to provide (16S,17S)-adduct 51 and a boron-mediated aldol reaction between enone 10 and aldehyde 9, exploiting unprecedented remote 1,6-stereoinduction, to give the (5S)-adduct 57.

  2. On the autarchic use of solely PIXE data in particulate matter source apportionment studies by receptor modeling

    Energy Technology Data Exchange (ETDEWEB)

    Lucarelli, F. [Department of Physics and Astronomy, University of Florence, Via G. Sansone 1, 50019 Sesto Fiorentino (Italy); National Institute of Nuclear Physics (INFN)-Florence, Via G. Sansone 1, 50019 Sesto Fiorentino (Italy); Nava, S., E-mail: nava@fi.infn.it [National Institute of Nuclear Physics (INFN)-Florence, Via G. Sansone 1, 50019 Sesto Fiorentino (Italy); Calzolai, G. [Department of Physics and Astronomy, University of Florence, Via G. Sansone 1, 50019 Sesto Fiorentino (Italy); Chiari, M. [National Institute of Nuclear Physics (INFN)-Florence, Via G. Sansone 1, 50019 Sesto Fiorentino (Italy); Giannoni, M.; Traversi, R.; Udisti, R. [Department of Chemistry, University of Florence, Via della Lastruccia 3, 50019 Sesto Fiorentino (Italy)

    2015-11-15

    Particle Induced X-ray Emission (PIXE) analysis of aerosol samples allows simultaneous detection of several elements, including important tracers of many particulate matter sources. This capability, together with the possibility of analyzing a high number of samples in very short times, makes PIXE a very effective tool for source apportionment studies by receptor modeling. However, important aerosol components, like nitrates, OC and EC, cannot be assessed by PIXE: this limitation may strongly compromise the results of a source apportionment study if based on PIXE data alone. In this work, an experimental dataset characterised by an extended chemical speciation (elements, EC–OC, ions) is used to test the effect of reducing input species in the application of one of the most widely used receptor model, namely Positive Matrix Factorization (PMF). The main effect of using only PIXE data is that the secondary nitrate source is not identified and the contribution of biomass burning is overestimated, probably due to the similar seasonal pattern of these two sources.

  3. A novel method based solely on FPGA units enabling measurement of time and charge of analog signals in Positron Emission Tomography

    CERN Document Server

    Pałka, M; Białas, P; Czerwiński, E; Kapłon, Ł; Kochanowski, A; Korcyl, G; Kowal, J; Kowalski, P; Kozik, T; Krzemień, W; Molenda, M; Moskal, P; Niedźwiecki, Sz; Pawlik, M; Raczyński, L; Rudy, Z; Salabura, P; Sharma, N G; Silarski, M; Słomski, A; Smyrski, J; Strzelecki, A; Wiślicki, W; Zieliński, M; Zoń, N

    2013-01-01

    This article presents a novel technique for precise measurement of time and charge based solely on FPGA (Field Programmable Gate Array) device and few satellite discrete electronic components used in Positron Emission Tomography (PET). Described approach simplifies electronic circuits, reduces the power consumption, lowers costs, merges front-end electronics with digital electronics and also makes more compact final design. Furthermore, it allows to measure time when analog signals cross a reference voltage at different threshold levels with a very high precision of $\\sim$ 10ps (rms) and thus enables sampling of signals in a voltage domain.

  4. Single nucleotide polymorphism array-based karyotyping in acute myeloid leukemia or myelodysplastic syndrome with trisomy 8 as the sole chromosomal abnormality.

    Science.gov (United States)

    Hahm, Chorong; Mun, Yeung Chul; Seong, Chu Myong; Han, Sung-Hee; Chung, Wha Soon; Huh, Jungwon

    2013-01-01

    The clinical heterogeneity of patients with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) with trisomy 8 as the sole abnormality may result from cytogenetically undetectable genetic changes. The purpose of this study was to identify hidden genomic aberrations not detected by metaphase cytogenetics (MC) using high-resolution single nucleotide polymorphism array (SNP-A)-based karyotyping in AML/MDS patients with a sole trisomy 8. The study group included 8 patients (3 AML and 5 MDS) and array-based karyotyping was done using whole-genome SNP-A (SNP 6.0 and SNP 2.7M). By SNP-A, additional genomic aberrations not detected by MC were identified in 2 patients: 1 AML patient exhibited a copy-neutral loss of heterozygosity (CN-LOH) of 3q21.1-q29 and 11q13.1-q25 and the other patient with MDS (refractory cytopenia with unilineage dysplasia) had CN-LOH of 2p25.3-p15. In particular, the latter patient progressed to AML 18 months after the diagnosis. In 3 patients, aberrations in addition to trisomy 8 were not identified by SNP-A. In the remaining 3 patients, SNP-A could not detect trisomy 8, while trisomy 8 was found in 25-67% of metaphase cells by MC. This study suggests that additional genomic aberrations may in fact be present even in cases of trisomy 8 as sole abnormality by MC, and SNP-A could be a useful karyotyping tool to identify hidden aberrations such as CN-LOH.

  5. Cloning, characterization of two female-specific AFLP markers and development of PCR-based sex identification method for the half-smooth tongue sole Cynoglossus semilaevis

    Directory of Open Access Journals (Sweden)

    Hongyu MA, Songlin CHEN, Jing LI, Jin-Zhen BI, Tianjun XU

    2009-08-01

    Full Text Available Two female-specific AFLP (amplified fragment length polymorphism markers (named CseF464 and CseF136 were isolated by using one selective primer combination (E-AGC/M-CTG from the genomic DNA of 20 females and 20 males of the half-smooth tongue sole Cynoglossus semilaevis. Both the markers were re-amplified, recovered from the agarose gels, cloned and sequenced. Bioinformatics analysis indicated that the length of the two markers were 468bp and 134bp, respectively, and the sequences showed no similarity to each other, as well as to the known sequences deposited in the GenBank database using BLASTn. Two pairs of SCAR (sequence characterized amplified regions primers were designed based on the sequences of the two female-specific markers. Furthermore, PCR-based genetic sex identification method was developed in Cynoglossus semilaevis. A specific fragment was amplified in all females but not in any males by using these SCAR primers on the initial 20 female and 20 male individuals of Cynoglossus semilaevis. The feasibility of the two SCAR primer pairs was confirmed in additional 100 individuals (50 females and 50 males. This allowed for reliable, rapid molecular identification of genetic sex of the species, genetic mapping on the sex chromosomes and better understanding of the sex determination and sex differentiation in the half-smooth tongue sole [Current Zoology 55 (4: 309–314, 2009].

  6. Oman metamorphic sole formation reveals early subduction dynamics

    Science.gov (United States)

    Soret, Mathieu; Agard, Philippe; Dubacq, Benoît; Plunder, Alexis; Ildefonse, Benoît; Yamato, Philippe; Prigent, Cécile

    2016-04-01

    Metamorphic soles correspond to m to ~500m thick tectonic slices welded beneath most of the large-scale ophiolites. They typically show a steep inverted metamorphic structure where the pressure and temperature conditions of crystallization increase upward (from 500±100°C at 0.5±0.2 GPa to 800±100°C at 1.0±0.2 GPa), with isograds subparallel to the contact with the overlying ophiolitic peridotite. The proportion of mafic rocks in metamorphic soles also increases from the bottom (meta-sediments rich) to the top (approaching the ophiolite peridotites). These soles are interpreted as the result of heat transfer from the incipient mantle wedge toward the nascent slab (associated with large-scale fluid transfer and possible shear heating) during the first My of intra-oceanic subduction (as indicated by radiometric ages). Metamorphic soles provide therefore major constraints on early subduction dynamics (i.e., thermal structure, fluid migration and rheology along the nascent slab interface). We present a detailed structural and petrological study of the metamorphic sole from 4 major cross-sections along the Oman ophiolite. We show precise pressure-temperature estimates obtained by pseudosection modelling and EBSD measurements performed on both the garnet-bearing and garnet-free high-grade sole. Results allow quantification of the micro-scale deformation and highlight differences in pressure-temperature-deformation conditions between the 4 different locations, showing that the inverted metamorphic gradient through the sole is not continuous in all locations. Based on these new constraints, we suggest a new tectonic-petrological model for the formation of metamorphic soles below ophiolites. This model involves the stacking of several homogeneous slivers of oceanic crust leading to the present-day structure of the sole. In this view, these thrusts are the result of rheological contrasts between the sole and the peridotite as the plate interface progressively cools down

  7. Effects-Based Operations: Air Power as the Sole Military Instrument of Power, Has it Matured Enough?

    Science.gov (United States)

    2006-04-01

    BACKGROUND He who controls the past, controls the future; and he who controls the present, controls the past. — George Orwell In order to enhance the...50. 77 Ibid., p. 51. 78 George W. Bush (address to Congress, Washington, DC, 20 September 2001). Available at: http://www.whitehouse.gov/news...bence.html (accessed 31 MAR 2006). Berg, Paul D. “Effects-Based Airpower and Space Power.” Air and Space Power Journal, Spring 2006: 17. Bush, George

  8. Novel high-resolution characterization of ancient DNA reveals C > U-type base modification events as the sole cause of post mortem miscoding lesions.

    Science.gov (United States)

    Brotherton, Paul; Endicott, Phillip; Sanchez, Juan J; Beaumont, Mark; Barnett, Ross; Austin, Jeremy; Cooper, Alan

    2007-01-01

    Ancient DNA (aDNA) research has long depended on the power of PCR to amplify trace amounts of surviving genetic material from preserved specimens. While PCR permits specific loci to be targeted and amplified, in many ways it can be intrinsically unsuited to damaged and degraded aDNA templates. PCR amplification of aDNA can produce highly-skewed distributions with significant contributions from miscoding lesion damage and non-authentic sequence artefacts. As traditional PCR-based approaches have been unable to fully resolve the molecular nature of aDNA damage over many years, we have developed a novel single primer extension (SPEX)-based approach to generate more accurate sequence information. SPEX targets selected template strands at defined loci and can generate a quantifiable redundancy of coverage; providing new insights into the molecular nature of aDNA damage and fragmentation. SPEX sequence data reveals inherent limitations in both traditional and metagenomic PCR-based approaches to aDNA, which can make current damage analyses and correct genotyping of ancient specimens problematic. In contrast to previous aDNA studies, SPEX provides strong quantitative evidence that C > U-type base modifications are the sole cause of authentic endogenous damage-derived miscoding lesions. This new approach could allow ancient specimens to be genotyped with unprecedented accuracy.

  9. Novel high-resolution characterization of ancient DNA reveals C > U-type base modification events as the sole cause of post mortem miscoding lesions

    Science.gov (United States)

    Brotherton, Paul; Endicott, Phillip; Sanchez, Juan J.; Beaumont, Mark; Barnett, Ross; Austin, Jeremy; Cooper, Alan

    2007-01-01

    Ancient DNA (aDNA) research has long depended on the power of PCR to amplify trace amounts of surviving genetic material from preserved specimens. While PCR permits specific loci to be targeted and amplified, in many ways it can be intrinsically unsuited to damaged and degraded aDNA templates. PCR amplification of aDNA can produce highly-skewed distributions with significant contributions from miscoding lesion damage and non-authentic sequence artefacts. As traditional PCR-based approaches have been unable to fully resolve the molecular nature of aDNA damage over many years, we have developed a novel single primer extension (SPEX)-based approach to generate more accurate sequence information. SPEX targets selected template strands at defined loci and can generate a quantifiable redundancy of coverage; providing new insights into the molecular nature of aDNA damage and fragmentation. SPEX sequence data reveals inherent limitations in both traditional and metagenomic PCR-based approaches to aDNA, which can make current damage analyses and correct genotyping of ancient specimens problematic. In contrast to previous aDNA studies, SPEX provides strong quantitative evidence that C > U-type base modifications are the sole cause of authentic endogenous damage-derived miscoding lesions. This new approach could allow ancient specimens to be genotyped with unprecedented accuracy. PMID:17715147

  10. Region 9 Sole Source Aquifers

    Data.gov (United States)

    U.S. Environmental Protection Agency — There are 7 polygons representing 6 individual sole source aquifer boundaries and one streamflow source area in California, Arizona, and Nevada. Various efforts were...

  11. EPA Region 1 Sole Source Aquifers

    Data.gov (United States)

    U.S. Environmental Protection Agency — This coverage contains boundaries of EPA-approved sole source aquifers. Sole source aquifers are defined as an aquifer designated as the sole or principal source of...

  12. Nine decades of North Sea sole and plaice distribution

    NARCIS (Netherlands)

    Engelhard, G.H.; Pinnegar, J.K.; Kell, L.T.; Rijnsdorp, A.D.

    2011-01-01

    Recent studies based mainly on research survey data suggest that within the North Sea, sole Solea solea and plaice Pleuronectes platessa have exhibited distribution shifts in recent decades—on average southward for sole and northward to deeper waters for plaice. Various hypotheses may account for su

  13. Sole Source Aquifers for NY and NJ

    Data.gov (United States)

    U.S. Environmental Protection Agency — This layer is the designated sole source aquifers of New York and New Jersey. A Sole Source Aquifer, is an aquifer that supplies 50% or more of the drinking water...

  14. Wuxia's Children Shoes sole: Touching Children's Heart

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    @@ Wuxia Children shoes sole company, founded in 1998, is the first professional children shoes sole business in Wenzhou city. It is located in Huanglong Commercial Center,Wenzhou city, Zhejiang province.

  15. A NEW DESIGN METHOD FOR FLAT FOOTWEAR SOLES

    Directory of Open Access Journals (Sweden)

    IONESCU Cozmin

    2016-05-01

    Full Text Available Carried research regarding footwear soles reveald that by moulding footwear details can be obtained in a wide variety of models. Shoe soles are complex three dimensional objects and for attaching them with the uppers, the interor countour of the soles has to correspond to the featherline contour of the last. That’s why, is necessary that soles design to be done with high accuracy and in strict accordance to the last. Nowadays, there are specialized software applications which can perform various computer aided design processes for footwear. Among the high performance systems used for the design of footwear soles and injection moulds for shoe soles, we may mention: Delcam Shoe Solution, Delcam PowerSHAPE-e, Padsy II and Padsy III, Shoe Master System, Lectra System, Parmel System and ATOS II System. This paper presents a 3D design method, developed by the authors, for footwear flat soles using PowerSHAPE-e software programm from of Delcam Crispin. The computer-aided design technique used in this paper highlights several important advantages that include: increased design quality; three dimensional viewing of soles, which can lead to immediate decisions, regarding the acceptance of newly developed models; it can be appreciated the complexity of mould cavities execution, without the need of making prototypes; the outlines of construction templates are accurately obtained for the mould cavities and for all size numbers; calculations can easily be done for determining the soles volume for the entire size number, with implications on estimating polymer blend consumption and so on.

  16. High-resolution genome-wide array-based comparative genome hybridization reveals cryptic chromosome changes in AML and MDS cases with trisomy 8 as the sole cytogenetic aberration.

    Science.gov (United States)

    Paulsson, K; Heidenblad, M; Strömbeck, B; Staaf, J; Jönsson, G; Borg, A; Fioretos, T; Johansson, B

    2006-05-01

    Although trisomy 8 as the sole chromosome aberration is the most common numerical abnormality in acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS), little is known about its pathogenetic effects. Considering that +8 is a frequent secondary change in AML/MDS, cryptic--possibly primary--genetic aberrations may occur in cases with trisomy 8 as the apparently single anomaly. However, no such hidden anomalies have been reported. We performed a high-resolution genome-wide array-based comparative genome hybridization (array CGH) analysis of 10 AML/MDS cases with isolated +8, utilizing a 32K bacterial artificial chromosome array set, providing >98% coverage of the genome with a resolution of 100 kb. Array CGH revealed intrachromosomal imbalances, not corresponding to known genomic copy number polymorphisms, in 4/10 cases, comprising nine duplications and hemizygous deletions ranging in size from 0.5 to 2.2 Mb. A 1.8 Mb deletion at 7p14.1, which had occurred prior to the +8, was identified in MDS transforming to AML. Furthermore, a deletion including ETV6 was present in one case. The remaining seven imbalances involved more than 40 genes. The present results show that cryptic genetic abnormalities are frequent in trisomy 8-positive AML/MDS cases and that +8 as the sole cytogenetic aberration is not always the primary genetic event.

  17. Reliable measurement of 3D foot bone angles based on the frame-of-reference derived from a sole of the foot

    Science.gov (United States)

    Kim, Taeho; Lee, Dong Yeon; Park, Jinah

    2016-03-01

    Clinical management of foot pathology requires accurate and robust measurement of the anatomical angles. In order to measure a 3D angle, recent approaches have adopted a landmark-based local coordinate system to establish bone angles used in orthopedics. These measurement methods mainly assess the relative angle between bones using a representative axis derived from the morphological feature of the bone and therefore, the results can be affected by bone deformities. In this study, we propose a method of deriving a global frame-of-reference to acquire consistent direction of the foot by extracting the undersurface of the foot from the CT image data. The two lowest positions of the foot skin are identified from the surface to define the base plane, and the direction from the hallux to the fourth toe is defined together to construct the global coordinate system. We performed the experiment on 10 volumes of foot CT images of healthy subjects to verify that the proposed method provides reliable measurements. We measured 3D angles for talus-calcaneus and talus-navicular using facing articular surfaces of paired bones. The angle was reported in 3 projection angles based on both coordinate systems defined by proposed global frame-of-reference and by CT image planes (saggital, frontal, and transverse). The result shows that the quantified angle using the proposed method considerably reduced the standard deviation (SD) against the angle using the conventional projection planes, and it was also comparable with the measured angles obtained from local coordinate systems of the bones. Since our method is independent from any individual local shape of a bone, unlike the measurement method using the local coordinate system, it is suitable for inter-subject comparison studies.

  18. An Individual-based Probabilistic Model for Fish Stock Simulation

    Directory of Open Access Journals (Sweden)

    Federico Buti

    2010-08-01

    Full Text Available We define an individual-based probabilistic model of a sole (Solea solea behaviour. The individual model is given in terms of an Extended Probabilistic Discrete Timed Automaton (EPDTA, a new formalism that is introduced in the paper and that is shown to be interpretable as a Markov decision process. A given EPDTA model can be probabilistically model-checked by giving a suitable translation into syntax accepted by existing model-checkers. In order to simulate the dynamics of a given population of soles in different environmental scenarios, an agent-based simulation environment is defined in which each agent implements the behaviour of the given EPDTA model. By varying the probabilities and the characteristic functions embedded in the EPDTA model it is possible to represent different scenarios and to tune the model itself by comparing the results of the simulations with real data about the sole stock in the North Adriatic sea, available from the recent project SoleMon. The simulator is presented and made available for its adaptation to other species.

  19. Use of styrene as sole carbon source by the fungus Exophiala oligosperma: optimization and modeling of biodegradation, pathway elucidation, and cell membrane composition.

    Science.gov (United States)

    Rene, Eldon R; Bernat, Przemysław; Długoński, Jerzy; Veiga, Maria C; Kennes, Christian

    2012-11-01

    Biodegradation of styrene by Exophiala sp. was tested at different initial concentrations (19.3-170.6 mgl(-1)), pH (2.8-8.7), and temperatures (19.8-45.1 °C), for 120 h according to a 2(3) full-factorial central composite design. The specific growth rate (SGR, per hour) and specific styrene utilization rate (SUR, milligrams of styrene per milligram of biomass per hour) values were used as the response variables for optimization purposes. The interactions between concentration and temperature (P=0.022), and pH and temperature (P=0.010) for SGR, and interactions between concentration and temperature (P=0.012) for SUR were found to be statistically significant. The optimal values for achieving high SGR (0.15 h(-1)) and SUR (0.3622 mg styrene mg(-1) biomass h(-1)) were calculated from the regression model equation. Those values are C(o)=89.1 mgl(-1), pH=5.4, and T=31.5 °C for SGR and C(o)=69.2 mgl(-1), pH=5.5, and T=32.4 °C for SUR. It was also observed that the Exophiala strain degrades styrene via phenylacetic acid, involving initial oxidation of the vinyl side chain. Besides, in the presence of styrene, changes in the fatty acids profile were also observed. It is hypothesized that an increasing amount of linoleic acid (18:2) may be involved in the protection of the fungus against toxic substrate.

  20. National Sole Source Aquifer GIS Layer

    Data.gov (United States)

    U.S. Environmental Protection Agency — This data set contains indexes and Esri shape files of boundaries of the designated sole source aquifers and related aquifer boundaries. Data provide a vector...

  1. A NEW 3D DESIGN METHOD FOR FOOTWEAR SOLES USING DELCAM PowerSHAPE-e SYSTEM

    Directory of Open Access Journals (Sweden)

    IONESCU Cozmin

    2016-05-01

    Full Text Available Design methods of soles and soles injection moulds must be accurate, timely and at the same time, accessible to a wide category of soles and injection moulds designers and manufacturers. For designing soles and injection moulds for soles, various dedicated CAD/CAM systems have been developed, such as: Delcam Shoe Solution (3D, Delcam PowerSHAPE-e (2D and 3D, Padsy II (2D and Padsy III (3D, Shoemaster System (2D and 3D, Lectra System (2D and 3D, Parmel System (2D and ATOS II System (3D. These systems are equipped with colour displays, plotters, digitizers, terminals and other equipment dedicated for computer aided design activities. Designing 3D soles models using computer systems enables the prevention of ambiguities inherited from 2D drawings, thus reducing errors and remanufacturing. Depending on the design complexity of soles, the technical means available for copying shoe soles and the technologies at the disposal of the soles manufacturers, soles and injection moulds designers adopt various design methods. Not all CAD/CAM systems are accessible for all users, because often their purchasing costs are high. Design method developed and presented in this paper, uses Delcam PowerSHAPE software program, which has the advantage that it can be accessed free of charge from the manufacturer's website. At the same time, this software program provides the user with all the necessary tools and instruments needed to design the most complex injection moulds and footwear sole.

  2. Design of Monitoring and Controlling Software of Footwear Sole Friction Based on Qt%基于Qt的鞋底摩擦力测控软件的设计

    Institute of Scientific and Technical Information of China (English)

    林贤贤; 吕冬华; 杨永杰

    2012-01-01

    鞋底的止滑性直接影响着鞋子穿用时的舒适性和安全性,止滑性主要由摩擦系数来表示,在一定范围内,摩擦系数越大,止滑性越好.系统通过测量作用于鞋底的拉力和压力,求得摩擦系数,从而来判断各种鞋子的安全性能,因此对拉力和压力的测量显得十分重要.软件的设计基于Qt开发环境,在这个环境下开发的软件有很好的移植性,根据鞋底拉力测控系统的要求,将通过串行通信实时接收、处理、控制、显示、绘图、保存采集到的拉力和压力数据.最后在系统测试的基础上,验证了软件的正确性且测量精度高.%Slip resistance of footwear sole affects the comfort and safety of shoes directly, and slip resistance is mainly expressed by the coefficient of friction. Within a certain range, the greater the coefficient of friction, the slip resistance is better. In order to determine the safety performance of shoes, the system will obtain the coefficient of friction by measuring the tension and pressure put on shoes, so it' s very important to do the measurement precisely. Based on Qt development environment and monitoring-controlling system of footwear sole friction, the software has good portability and it will execute real-time receiving, processing, controlling, displaying, drawing and saving collected data of tension and pressure via serial communication. Finally, on the basis of the system test, the correctness of the software and measurement accuracy are verified.

  3. Lichen nitidus of palms and soles

    Directory of Open Access Journals (Sweden)

    Gandhi Vijay

    1998-01-01

    Full Text Available Lichen nitidus occurs uncommonly on the palms and soles and has an unusual morphology at these sites. Two patients who presented with lesions on the palms and soles are reported. The first patient had rough papules with prominent keratotic plugs. In the second patient, the lesion was an irregular plaque with peripheral papules showing keratotic plugs. Both patients had typical lesions elsewhere on the body. Histopathology confirmed the diagnosis. Awareness of this variant will help in prompt recognition of the condition.

  4. Model-based geostatistics

    CERN Document Server

    Diggle, Peter J

    2007-01-01

    Model-based geostatistics refers to the application of general statistical principles of modeling and inference to geostatistical problems. This volume provides a treatment of model-based geostatistics and emphasizes on statistical methods and applications. It also features analyses of datasets from a range of scientific contexts.

  5. CONTRIBUTIONS TO THE DIVERSIFICATION OF FOOTWEAR SOLES FOR DIRECT SOLING INJECTION USING MOULDS WITH INTERCHANGEABLE PARTS

    Directory of Open Access Journals (Sweden)

    IONESCU Cozmin

    2016-09-01

    Full Text Available One solution for attaching soles on footwear is to inject them directly into the upper part using moulds with unique cavities. Injection moulds are manufactured for each sole design, for each foot, right and left, and for each size number. As a result of the market demand for a large number of soles designs, the execution costs of moulds for each of them are substantial. In the case of small manufacturers, injection moulds wear out morally long before they wear out physically. This paper will present some design solutions for moulds that have reusable parts that can be used from one sole design to another, without changing the entire mould. Using these moulds, soles design can be modified by interchanging some modules which are fitted into the main mould cavities. These solutions represent a cheaper and faster alternative for classic moulds, with unique single cavities.

  6. Metamorphic sole formation and early plate interface rheology: Insights from Griggs apparatus experiments

    Science.gov (United States)

    Soret, Mathieu; Agard, Philippe; Dubacq, Benoît; Hirth, Greg; Yamato, Philippe; Ildefonse, Benoît; Prigent, Cécile

    2016-04-01

    Metamorphic soles correspond to m to ~500 m thick highly strained metamorphic rock units found beneath mylonitic banded peridotites at the base of large-scale ophiolites, as exemplified in Oman. Metamorphic soles are mainly composed of metabasalts deriving from the downgoing oceanic lithosphere and metamorphosed up to granulite-facies conditions by heat transfer from the mantle wedge. Pressure-temperature peak conditions are usually estimated at 1.0±0.2 GPa and 800±100°C. The absence of HP-LT metamorphism overprint implies that metamorphic soles have been formed and exhumed during subduction infancy. In this view, metamorphic soles were strongly deformed during their accretion to the mantle wedge (corresponding, now, to the base of the ophiolite). Therefore, metamorphic soles and banded peridotites are direct witnesses of the dynamics of early subduction zones, in terms of thermal structure, fluid migration and rheology evolution across the nascent slab interface. Based on fieldwork and EBSD analyses, we present a detailed (micro-) structural study performed on samples coming from the Sumeini window, the better-preserved cross-section of the metamorphic sole of Oman. Large differences are found in the deformation (CPO, grain size, aspect ratio) of clinopyroxene, amphibole and plagioclase, related to mineralogical changes linked with the distance to the peridotite contact (e.g., hardening due to the appearance of garnet and clinopyroxene). To model the incipient slab interface in laboratory, we carried out 5 hydrostatic annealing and simple-shear experiments on Griggs solid-medium apparatus. Deformation experiments were conducted at axial strain rates of 10-6 s-1. Fine-grained amphibolite was synthetized by adding 1 wt.% water to a (Mid-Ocean Ridge) basalt powder as a proxy for the metamorphic sole (amphibole + plagioclase + clinopyroxene ± garnet assemblage). To synthetize garnet, 2 experiments were carried out in hydrostatic conditions and with deformation at

  7. Characteristics of Rural Communities with a Sole, Independently Owned Pharmacy.

    Science.gov (United States)

    Nattinger, Matthew; Ullrich, Fred; Mueller, Keith J

    2015-04-01

    Prior RUPRI Center policy briefs have described the role of rural pharmacies in providing many essential clinical services (in addition to prescription and nonprescription medications), such as blood pressure monitoring, immunizations, and diabetes counseling, and the adverse effects of Medicare Part D negotiated networks on the financial viability of rural pharmacies.1 Because rural pharmacies play such a broad role in health care delivery, pharmacy closures can sharply reduce access to essential health care services in rural and underserved communities. These closures are of particular concern in rural areas served by a sole, independently owned pharmacy (i.e., a pharmacy unaffiliated with a chain or franchise). This policy brief characterizes the population of rural areas served by a sole, independently owned pharmacy. Dependent on a sole pharmacy, these areas are at highest risk to lose access to many essential clinical services. Key Findings. (1) In 2014 over 2.7 million people lived in 663 rural communities served by a sole, independently owned pharmacy. (2) More than one-quarter of these residents (27.9 percent) were living below 150 percent of the federal poverty level. (3) Based on estimates from 2012, a substantial portion of the residents of these areas were dependent on public insurance (i.e., Medicare and/or Medicaid, 20.5 percent) or were uninsured (15.0 percent). (4) If the sole, independent retail pharmacy in these communities were to close, the next closest retail pharmacy would be over 10 miles away for a majority of rural communities (69.7 percent).

  8. Whole-body acid-base modeling revisited

    DEFF Research Database (Denmark)

    Ring, Troels; Nielsen, Søren

    2017-01-01

    The textbook account of whole-body acid-base balance in terms of endogenous acid production, renal net acid excretion and gastrointestinal alkali absorption which is the only comprehensive model around, has never been applied in clinical practice or been formally validated. In order to improve...... understanding of acid-base modeling, we managed to write up this conventional model as an expression solely on urine chemistry. Renal net acid excretion and endogenous acid production was already formulated in terms of urine chemistry, and we could from the literature also see gastrointestinal alkali absorption...

  9. Impact of climate and hydrodynamics on sole larval immigration towards the Tagus estuary, Portugal

    Science.gov (United States)

    Vinagre, C.; Costa, M. J.; Cabral, H. N.

    2007-12-01

    Spawning grounds of the soles, Solea solea and Solea senegalensis, are distant from the estuarine nurseries where juveniles concentrate. Recruitment of these species is highly dependent on the success of the larval migration towards the inshore nursery grounds. Unfavourable climate and hydrodynamic circulation may lead to high mortality rates at this stage. The relation between river drainage, NAO index and the North-South wind component intensity over the three months prior to the end of the estuarine colonization and the densities of S. solea and S. senegalensis in the nursery grounds were investigated for both species based on a discontinuous historical dataset (from 1988 to 2006) for the Tagus estuary. Multiple linear regression models were developed for sole density and environmental data (separately for each species). Results showed that river drainage is positively correlated with juveniles' densities of both species, possibly due to the existence of chemical cues used by larvae for movement orientation. NAO index and the North-South wind component intensity relations with soles densities were non-significant. It was concluded that the high complexity of the Portuguese upwelling system makes it hard to detect causal relations of the environmental variables tested. The importance of river flow for coastal ecosystems was stressed. Since climate change scenarios predict a strong decrease in rain fall over the Portuguese river basins, as well as a concentrated period of heavy rain in winter, it was hypothesised that future river drainage decrease over much of the year may lead to lower recruitment success for soles, especially for S. senegalensis.

  10. Web Based VRML Modelling

    NARCIS (Netherlands)

    Kiss, S.

    2001-01-01

    Presents a method to connect VRML (Virtual Reality Modeling Language) and Java components in a Web page using EAI (External Authoring Interface), which makes it possible to interactively generate and edit VRML meshes. The meshes used are based on regular grids, to provide an interaction and modeling

  11. Climate-based species distribution models for Armillaria solidipes in Wyoming: A preliminary assessment

    Science.gov (United States)

    John W. Hanna; James T. Blodgett; Eric W. I. Pitman; Sarah M. Ashiglar; John E. Lundquist; Mee-Sook Kim; Amy L. Ross-Davis; Ned B. Klopfenstein

    2014-01-01

    As part of an ongoing project to predict Armillaria root disease in the Rocky Mountain zone, this project predicts suitable climate space (potential distribution) for A. solidipes in Wyoming and associated forest areas at risk to disease caused by this pathogen. Two bioclimatic models are being developed. One model is based solely on verified locations of A. solidipes...

  12. Whole body acid-base modeling revisited.

    Science.gov (United States)

    Ring, Troels; Nielsen, Søren

    2017-04-01

    The textbook account of whole body acid-base balance in terms of endogenous acid production, renal net acid excretion, and gastrointestinal alkali absorption, which is the only comprehensive model around, has never been applied in clinical practice or been formally validated. To improve understanding of acid-base modeling, we managed to write up this conventional model as an expression solely on urine chemistry. Renal net acid excretion and endogenous acid production were already formulated in terms of urine chemistry, and we could from the literature also see gastrointestinal alkali absorption in terms of urine excretions. With a few assumptions it was possible to see that this expression of net acid balance was arithmetically identical to minus urine charge, whereby under the development of acidosis, urine was predicted to acquire a net negative charge. The literature already mentions unexplained negative urine charges so we scrutinized a series of seminal papers and confirmed empirically the theoretical prediction that observed urine charge did acquire negative charge as acidosis developed. Hence, we can conclude that the conventional model is problematic since it predicts what is physiologically impossible. Therefore, we need a new model for whole body acid-base balance, which does not have impossible implications. Furthermore, new experimental studies are needed to account for charge imbalance in urine under development of acidosis.

  13. Prey consumption by the juvenile soles, Solea solea and Solea senegalensis, in the Tagus estuary, Portugal

    Science.gov (United States)

    Vinagre, C.; Cabral, H. N.

    2008-06-01

    The soles Solea solea and Solea senegalensis are marine flatfish that use coastal and estuarine nursery grounds, which generally present high food availability, refuge from predators and favourable conditions for rapid growth. Two important nursery grounds for these species juveniles have been identified in the Tagus estuary, one in the upper part of the estuary (nursery A) and another in the south bank (nursery B). While S. solea is only present at the uppermost nursery area, S. senegalensis is present at both nurseries. Although they are among the most important predators in these nursery grounds, there are no estimates on their food consumption or on the carrying capacity of the system for soles. The Elliott and Persson [1978. The estimation of daily rates of food consumption for fish. Journal of Animal Ecology 47, 977-993] model was used to estimate food consumption of both species juveniles in both nursery areas, taking into account gastric evacuation rates (previously determined) and 24 h sampling surveys, based on beam-trawl catches carried out every 3 h, in the summer of 1995. Monthly beam trawls were performed to determine sole densities over the summer. Density estimates and daily food consumption values were used to calculate total consumption over the summer period. Sediment samples were taken for the estimation of prey densities and total biomass in the nursery areas. Daily food consumption was lower for S. solea (0.030 g wet weight d -1) than for S. senegalensis (0.075 g wet weight d -1). It was concluded that thermal stress may be an important factor hindering S. solea's food consumption in the warmer months. Total consumption of S. solea over the summer (90 days) was estimated to be 97 kg (wet weight). Solea senegalensis total consumption in nursery A was estimated to be 103 kg, while in nursery B it was 528 kg. Total prey biomass estimated for nursery A was 300 tonnes, while for nursery B it was 58 tonnes. This suggests that food is not a limiting

  14. CONTRIBUTIONS TO DIVERSIFY SOLES MOULDS THAT FORMS DIRECTLY ON FACES SHOES

    Directory of Open Access Journals (Sweden)

    IONESCU Cozmin

    2015-05-01

    Full Text Available The classical moulds which are currently used for forming the soles directly on the uppers, allow obtaining one sole model. One mould for each foot is made, and at least one mould for each size number in the size number series. To manufacture one single sole model in the sizes series an average set of 16 moulds are needed. Changing the model implies the entire production of a new set of moulds. Therefore, a large diversification of the soles requires the manufacturing a quantity of moulds sets equal with the quantity of sole models. In this paper are presented solutions to obtain more cavity shapes in the same mould, through the use of modular interchangeable pieces. The moulds with versatile cavities have the same functional characteristics as the moulds with unique cavities, are usable on the same type of machines and can be used independently or together with the classical moulds. A brief analysis on the technological processes for manufacturing moulds with versatile cavities reveals a significant lowering of the manufacturing time for moulds in which will be obtained other sole models. This is due to the fact that some of the mould parts are reused. In conclusion, the producers that chose this type of moulds can launch on the market new models in a shorter time and at lower prices.

  15. Model-based target and background characterization

    Science.gov (United States)

    Mueller, Markus; Krueger, Wolfgang; Heinze, Norbert

    2000-07-01

    Up to now most approaches of target and background characterization (and exploitation) concentrate solely on the information given by pixels. In many cases this is a complex and unprofitable task. During the development of automatic exploitation algorithms the main goal is the optimization of certain performance parameters. These parameters are measured during test runs while applying one algorithm with one parameter set to images that constitute of image domains with very different domain characteristics (targets and various types of background clutter). Model based geocoding and registration approaches provide means for utilizing the information stored in GIS (Geographical Information Systems). The geographical information stored in the various GIS layers can define ROE (Regions of Expectations) and may allow for dedicated algorithm parametrization and development. ROI (Region of Interest) detection algorithms (in most cases MMO (Man- Made Object) detection) use implicit target and/or background models. The detection algorithms of ROIs utilize gradient direction models that have to be matched with transformed image domain data. In most cases simple threshold calculations on the match results discriminate target object signatures from the background. The geocoding approaches extract line-like structures (street signatures) from the image domain and match the graph constellation against a vector model extracted from a GIS (Geographical Information System) data base. Apart from geo-coding the algorithms can be also used for image-to-image registration (multi sensor and data fusion) and may be used for creation and validation of geographical maps.

  16. EPA Region 6 Sole Source Aquifers in Louisiana, Geographic NAD83, EPA (1996) [sole_source_aquifers_LA_EPA_1996

    Data.gov (United States)

    Louisiana Geographic Information Center — Polygon layer of EPA Region 6 sole source aquifers in Louisiana. The sole source aquifers represented are Chicot and Southern Hills in Louisiana/Mississippi.

  17. Sole larval supply to coastal nurseries: Interannual variability and connectivity at interregional and interpopulation scales

    Science.gov (United States)

    Savina, M.; Lunghi, M.; Archambault, B.; Baulier, L.; Huret, M.; Le Pape, O.

    2016-05-01

    Simulating fish larval drift helps assess the sensitivity of recruitment variability to early life history. An individual-based model (IBM) coupled to a hydrodynamic model was used to simulate common sole larval supply from spawning areas to coastal and estuarine nursery grounds at the meta-population scale (4 assessed stocks), from the southern North Sea to the Bay of Biscay (Western Europe) on a 26-yr time series, from 1982 to 2007. The IBM allowed each particle released to be transported by currents, to grow depending on temperature, to migrate vertically depending on development stage, to die along pelagic stages or to settle on a nursery, representing the life history from spawning to metamorphosis. The model outputs were analysed to explore interannual patterns in the amounts of settled sole larvae at the population scale; they suggested: (i) a low connectivity between populations at the larval stage, (ii) a moderate influence of interannual variation in the spawning biomass, (iii) dramatic consequences of life history on the abundance of settling larvae and (iv) the effects of climate variability on the interannual variability of the larvae settlement success.

  18. Why Observable Space Is Solely Three Dimensional

    CERN Document Server

    Rabinowitz, Mario

    2015-01-01

    Quantum (and classical) binding energy considerations in n-dimensional space indicate that atoms (and planets) can only exist in three-dimensional space. This is why observable space is solely 3-dimensional. Both a novel Virial theorem analysis, and detailed classical and quantum energy calculations for 3-space circular and elliptical orbits indicate that they have no orbital binding energy in greater than 3-space. The same energy equation also excludes the possibility of atom-like bodies in strictly 1 and 2-dimensions. A prediction is made that in the search for deviations from r^-2 of the gravitational force at sub-millimeter distances such a deviation must occur at < ~ 10^-10 m (or < ~10^-12 m considering muoniom), since atoms would disintegrate if the curled up dimensions of string theory were larger than this. Callender asserts that the often-repeated claim in previous work that stable orbits are possible in only three dimensions is not even remotely established. The binding energy analysis herein ...

  19. Model-based approach for elevator performance estimation

    Science.gov (United States)

    Esteban, E.; Salgado, O.; Iturrospe, A.; Isasa, I.

    2016-02-01

    In this paper, a dynamic model for an elevator installation is presented in the state space domain. The model comprises both the mechanical and the electrical subsystems, including the electrical machine and a closed-loop field oriented control. The proposed model is employed for monitoring the condition of the elevator installation. The adopted model-based approach for monitoring employs the Kalman filter as an observer. A Kalman observer estimates the elevator car acceleration, which determines the elevator ride quality, based solely on the machine control signature and the encoder signal. Finally, five elevator key performance indicators are calculated based on the estimated car acceleration. The proposed procedure is experimentally evaluated, by comparing the key performance indicators calculated based on the estimated car acceleration and the values obtained from actual acceleration measurements in a test bench. Finally, the proposed procedure is compared with the sliding mode observer.

  20. Sole means navigation and integrity through hybrid Loran-C and NAVSTAR GPS

    Science.gov (United States)

    Vangraas, Frank

    1990-01-01

    A sole means navigation system does not only call for integrity, but also for coverage, reliability, availability and accuracy. Even though ground monitored GPS will provide integrity, availability is still not sufficient. One satellite outage can affect a large service area for several hours per day. The same holds for differential GPS; a total satellite outage cannot be corrected for. To obtain sufficient coverage, extra measurements are needed, either in the form of extra GPS satellites (expensive) or through redundant measurements from other systems. LORAN-C is available and will, hybridized with GPS, result in a system that has the potential to satisfy the requirements for a sole means navigation system for use in the continental United States. Assumptions are made about the qualification sole means, mainly based on current sole means systems such as VOR/DME. In order to allow for system design that will satisfy sole means requirements, it is recommended that a definition of a sole means navigation system be established. This definition must include requirements for availability, reliability, and integrity currently not specified. In addition to the definition of a sole means navigation system, certification requirements must be established for hybrid navigation systems. This will allow for design and production of a new generation of airborne navigation systems that will reduce overall system costs and simplify training procedures.

  1. Model Based Definition

    Science.gov (United States)

    Rowe, Sidney E.

    2010-01-01

    In September 2007, the Engineering Directorate at the Marshall Space Flight Center (MSFC) created the Design System Focus Team (DSFT). MSFC was responsible for the in-house design and development of the Ares 1 Upper Stage and the Engineering Directorate was preparing to deploy a new electronic Configuration Management and Data Management System with the Design Data Management System (DDMS) based upon a Commercial Off The Shelf (COTS) Product Data Management (PDM) System. The DSFT was to establish standardized CAD practices and a new data life cycle for design data. Of special interest here, the design teams were to implement Model Based Definition (MBD) in support of the Upper Stage manufacturing contract. It is noted that this MBD does use partially dimensioned drawings for auxiliary information to the model. The design data lifecycle implemented several new release states to be used prior to formal release that allowed the models to move through a flow of progressive maturity. The DSFT identified some 17 Lessons Learned as outcomes of the standards development, pathfinder deployments and initial application to the Upper Stage design completion. Some of the high value examples are reviewed.

  2. Evidence-based guidelines of the spanish psoriasis group on the use of biologic therapy in patients with psoriasis in difficult-to-treat sites (nails, scalp, palms, and soles).

    Science.gov (United States)

    Sánchez-Regaña, M; Aldunce Soto, M J; Belinchón Romero, I; Ribera Pibernat, M; Lafuente-Urrez, R F; Carrascosa Carrillo, J M; Ferrándiz Foraster, C; Puig Sanz, L; Daudén Tello, E; Vidal Sarró, D; Ruiz-Villaverde, R; Fonseca Capdevila, E; Rodríguez Cerdeira, M C; Alsina Gibert, M M; Herrera Acosta, E; Marrón Moya, S E

    2014-12-01

    Psoriatic lesions affecting the scalp, nails, palms, and the soles of the feet are described as difficult-to-treat psoriasis and require specific management. Involvement of these sites often has a significant physical and emotional impact on the patient and the lesions are difficult to control with topical treatments owing to inadequate penetration of active ingredients and the poor cosmetic characteristics of the vehicles used. Consequently, when difficult-to-treat sites are involved, psoriasis can be considered severe even though the lesions are not extensive. Scant information is available about the use of biologic therapy in this setting, and published data generally comes from clinical trials of patients who also had moderate to severe extensive lesions or from small case series and isolated case reports. In this article we review the quality of the scientific evidence for the 4 biologic agents currently available in Spain (infliximab, etanercept, adalimumab, and ustekinumab) and report level i evidence for the use of biologics to treat nail psoriasis (level of recommendation A) and a somewhat lower level of evidence in the case of scalp involvement and palmoplantar psoriasis. Copyright © 2013 Elsevier España, S.L.U. y AEDV. All rights reserved.

  3. `Models of' versus `Models for'. Toward an Agent-Based Conception of Modeling in the Science Classroom

    Science.gov (United States)

    Gouvea, Julia; Passmore, Cynthia

    2017-03-01

    The inclusion of the practice of "developing and using models" in the Framework for K-12 Science Education and in the Next Generation Science Standards provides an opportunity for educators to examine the role this practice plays in science and how it can be leveraged in a science classroom. Drawing on conceptions of models in the philosophy of science, we bring forward an agent-based account of models and discuss the implications of this view for enacting modeling in science classrooms. Models, according to this account, can only be understood with respect to the aims and intentions of a cognitive agent (models for), not solely in terms of how they represent phenomena in the world (models of). We present this contrast as a heuristic— models of versus models for—that can be used to help educators notice and interpret how models are positioned in standards, curriculum, and classrooms.

  4. Synchronous formation of the metamorphic sole and igneous crust of the Semail ophiolite: New constraints on the tectonic evolution during ophiolite formation from high-precision U-Pb zircon geochronology

    Science.gov (United States)

    Rioux, Matthew; Garber, Joshua; Bauer, Ann; Bowring, Samuel; Searle, Michael; Kelemen, Peter; Hacker, Bradley

    2016-10-01

    The Semail (Oman-United Arab Emirates) and other Tethyan-type ophiolites are underlain by a sole consisting of greenschist- to granulite-facies metamorphic rocks. As preserved remnants of the underthrust plate, sole exposures can be used to better understand the formation and obduction of ophiolites. Early models envisioned that the metamorphic sole of the Semail ophiolite formed as a result of thrusting of the hot ophiolite lithosphere over adjacent oceanic crust during initial emplacement; however, calculated pressures from granulite-facies mineral assemblages in the sole suggest the metamorphic rocks formed at >35 km depth, and are too high to be explained by the currently preserved thickness of ophiolite crust and mantle (up to 15-20 km). We have used high-precision U-Pb zircon dating to study the formation and evolution of the metamorphic sole at two well-studied localities. Our previous research and new results show that the ophiolite crust formed from 96.12-95.50 Ma. Our new dates from the Sumeini and Wadi Tayin sole localities indicate peak metamorphism at 96.16 and 94.82 Ma (±0.022 to 0.035 Ma), respectively. The dates from the Sumeini sole locality show for the first time that the metamorphic rocks formed either prior to or during formation of the ophiolite crust, and were later juxtaposed with the base of the ophiolite. These data, combined with existing geochemical constraints, are best explained by formation of the ophiolite in a supra-subduction zone setting, with metamorphism of the sole rocks occurring in a subducted slab. The 1.3 Ma difference between the Wadi Tayin and Sumeini dates indicates that, in contrast to current models, the highest-grade rocks at different sole localities underwent metamorphism, and may have returned up the subduction channel, at different times.

  5. The complete mitochondrial genome of the Senegal sole, Solea senegalensis Kaup. Comparative analysis of tandem repeats in the control region among soles.

    Science.gov (United States)

    Manchado, Manuel; Catanese, Gaetano; Ponce, Marian; Funes, Victoria; Infante, Carlos

    2007-06-01

    The complete nucleotide sequence of the mitochondrial genome for the Senegal sole Solea senegalensis Kaup was determined. The mitochondrial DNA was 16,659 base pairs (bp) in length. Sequence features of the 13 protein-coding genes, two ribosomal RNAs and 22 transfer RNAs are described. The non-coding control region (1017 bp) was compared with those of the closely related soles Solea solea and Solea lascaris. The typical conservative blocks were identified. A cluster of 42 and 22 tandemly arrayed repeats was detected near the 3' end of control region in S. solea and S. lascaris, respectively. On the contrary, only two (93.8% of haplotypes) or three copies (6.2%) of an 8-bp repeated sequence motif was found in S. senegalensis. Phylogenetic analysis showed that 7 out of 9 of haplotypes bearing three copies grouped in a separate cluster. Possible mechanisms influencing the evolution of control region among soles are discussed.

  6. 21 CFR 1271.10 - Are my HCT/P's regulated solely under section 361 of the PHS Act and the regulations in this part...

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Are my HCT/P's regulated solely under section 361..., AND CELLULAR AND TISSUE-BASED PRODUCTS General Provisions § 1271.10 Are my HCT/P's regulated solely.../P is regulated solely under section 361 of the PHS Act and the regulations in this part if it...

  7. Reduced model-based decision-making in schizophrenia.

    Science.gov (United States)

    Culbreth, Adam J; Westbrook, Andrew; Daw, Nathaniel D; Botvinick, Matthew; Barch, Deanna M

    2016-08-01

    Individuals with schizophrenia have a diminished ability to use reward history to adaptively guide behavior. However, tasks traditionally used to assess such deficits often rely on multiple cognitive and neural processes, leaving etiology unresolved. In the current study, we adopted recent computational formalisms of reinforcement learning to distinguish between model-based and model-free decision-making in hopes of specifying mechanisms associated with reinforcement-learning dysfunction in schizophrenia. Under this framework, decision-making is model-free to the extent that it relies solely on prior reward history, and model-based if it relies on prospective information such as motivational state, future consequences, and the likelihood of obtaining various outcomes. Model-based and model-free decision-making was assessed in 33 schizophrenia patients and 30 controls using a 2-stage 2-alternative forced choice task previously demonstrated to discern individual differences in reliance on the 2 forms of reinforcement-learning. We show that, compared with controls, schizophrenia patients demonstrate decreased reliance on model-based decision-making. Further, parameter estimates of model-based behavior correlate positively with IQ and working memory measures, suggesting that model-based deficits seen in schizophrenia may be partially explained by higher-order cognitive deficits. These findings demonstrate specific reinforcement-learning and decision-making deficits and thereby provide valuable insights for understanding disordered behavior in schizophrenia. (PsycINFO Database Record

  8. 40 CFR 1042.620 - Engines used solely for competition.

    Science.gov (United States)

    2010-07-01

    ... CFR 1068.101(b)(4). (f) You must permanently label engines exempted under this section to clearly... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Engines used solely for competition... Special Compliance Provisions § 1042.620 Engines used solely for competition. The provisions of...

  9. Cluster Based Text Classification Model

    DEFF Research Database (Denmark)

    2011-01-01

    We propose a cluster based classification model for suspicious email detection and other text classification tasks. The text classification tasks comprise many training examples that require a complex classification model. Using clusters for classification makes the model simpler and increases th...... datasets. Our model also outperforms A Decision Cluster Classification (ADCC) and the Decision Cluster Forest Classification (DCFC) models on the Reuters-21578 dataset....

  10. Method for gesture based modeling

    DEFF Research Database (Denmark)

    2006-01-01

    A computer program based method is described for creating models using gestures. On an input device, such as an electronic whiteboard, a user draws a gesture which is recognized by a computer program and interpreted relative to a predetermined meta-model. Based on the interpretation, an algorithm...... is assigned to the gesture drawn by the user. The executed algorithm may, for example, consist in creating a new model element, modifying an existing model element, or deleting an existing model element....

  11. KINETIC ASSESSMENT OF GOLF SHOE OUTER SOLE DESIGN FEATURES

    Directory of Open Access Journals (Sweden)

    Rosemary J. Dyson

    2009-12-01

    Full Text Available This study assessed human kinetics in relation to golf shoe outer sole design features during the golf swing using a driver club by measuring both within the shoe, and beneath the shoe at the natural grass interface. Three different shoes were assessed: metal 7- spike shoe, alternative 7-spike shoe, and a flat soled shoe. In-shoe plantar pressure data were recorded using Footscan RS International pressure insoles and sampling at 500 Hz. Simultaneously ground reaction force at the shoe outer sole was measured using 2 natural grass covered Kistler force platforms and 1000 Hz data acquisition. Video recording of the 18 right-handed golfers at 200 Hz was undertaken while the golfer performed 5 golf shots with his own driver in each type of shoe. Front foot (nearest to shot direction maximum vertical force and torque were greater than at the back foot, and there was no significant difference related to the shoe type. Wearing the metal spike shoe when using a driver was associated with more torque generation at the back foot (p < 0. 05 than when the flat soled shoe was worn. Within shoe regional pressures differed significantly with golf shoe outer sole design features (p < 0.05. Comparison of the metal spike and alternative spike shoe results provided indications of the quality of regional traction on the outer sole. Potential golf shoe outer sole design features and traction were presented in relation to phases of the golf swing movement. Application of two kinetic measurement methods identified that moderated (adapted muscular control of foot and body movement may be induced by golf shoe outer sole design features. Ground reaction force measures inform comparisons of overall shoe functional performance, and insole pressure measurements inform comparisons of the underfoot conditions induced by specific regions of the golf shoe outer sole

  12. Model Construct Based Enterprise Model Architecture and Its Modeling Approach

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    In order to support enterprise integration, a kind of model construct based enterprise model architecture and its modeling approach are studied in this paper. First, the structural makeup and internal relationships of enterprise model architecture are discussed. Then, the concept of reusable model construct (MC) which belongs to the control view and can help to derive other views is proposed. The modeling approach based on model construct consists of three steps, reference model architecture synthesis, enterprise model customization, system design and implementation. According to MC based modeling approach a case study with the background of one-kind-product machinery manufacturing enterprises is illustrated. It is shown that proposal model construct based enterprise model architecture and modeling approach are practical and efficient.

  13. Usage of network services among sole holders

    Directory of Open Access Journals (Sweden)

    Szilvia Botos

    2011-11-01

    Full Text Available In the information society information means new production factor for the agri-food economy. The existence of appropriate information at the appropriate time determine significantly the efficiency of farming. Nowadays we can get information the most quickly by internet, so broadband developments in rural regions have become more and more important. Since the importance of e-administration is growing, broadband internet access is also important for agri-enterprises, because it allows fast access for law regulations and orders and they can find information about procurement and sales opportunities. In the article firstly we give a brief outline about the importance of internet access and the characteristics of broadband infrastructure in rural areas. After that we show how farmers use internet services and for what purposes, based on results of our questionnaire. Based on our examination, our network infrastructure and the usage of e-services are lagging behind other more developed European countries. In underdeveloped regions information society technologies can help to small agricultural enterprises to be viable and competitive.

  14. HMM-based Trust Model

    DEFF Research Database (Denmark)

    ElSalamouny, Ehab; Nielsen, Mogens; Sassone, Vladimiro

    2010-01-01

    with their dynamic behaviour. Using Hidden Markov Models (HMMs) for both modelling and approximating the behaviours of principals, we introduce the HMM-based trust model as a new approach to evaluating trust in systems exhibiting dynamic behaviour. This model avoids the fixed behaviour assumption which is considered...... the major limitation of existing Beta trust model. We show the consistency of the HMM-based trust model and contrast it against the well known Beta trust model with the decay principle in terms of the estimation precision....

  15. Model-Based Reasoning

    Science.gov (United States)

    Ifenthaler, Dirk; Seel, Norbert M.

    2013-01-01

    In this paper, there will be a particular focus on mental models and their application to inductive reasoning within the realm of instruction. A basic assumption of this study is the observation that the construction of mental models and related reasoning is a slowly developing capability of cognitive systems that emerges effectively with proper…

  16. Model-based Software Engineering

    DEFF Research Database (Denmark)

    2010-01-01

    The vision of model-based software engineering is to make models the main focus of software development and to automatically generate software from these models. Part of that idea works already today. But, there are still difficulties when it comes to behaviour. Actually, there is no lack in models...

  17. Model-based Software Engineering

    DEFF Research Database (Denmark)

    2010-01-01

    The vision of model-based software engineering is to make models the main focus of software development and to automatically generate software from these models. Part of that idea works already today. But, there are still difficulties when it comes to behaviour. Actually, there is no lack in models...

  18. Principles of models based engineering

    Energy Technology Data Exchange (ETDEWEB)

    Dolin, R.M.; Hefele, J.

    1996-11-01

    This report describes a Models Based Engineering (MBE) philosophy and implementation strategy that has been developed at Los Alamos National Laboratory`s Center for Advanced Engineering Technology. A major theme in this discussion is that models based engineering is an information management technology enabling the development of information driven engineering. Unlike other information management technologies, models based engineering encompasses the breadth of engineering information, from design intent through product definition to consumer application.

  19. Element-Based Computational Model

    Directory of Open Access Journals (Sweden)

    Conrad Mueller

    2012-02-01

    Full Text Available A variation on the data-flow model is proposed to use for developing parallel architectures. While the model is a data driven model it has significant differences to the data-flow model. The proposed model has an evaluation cycleof processing elements (encapsulated data that is similar to the instruction cycle of the von Neumann model. The elements contain the information required to process them. The model is inherently parallel. An emulation of the model has been implemented. The objective of this paper is to motivate support for taking the research further. Using matrix multiplication as a case study, the element/data-flow based model is compared with the instruction-based model. This is done using complexity analysis followed by empirical testing to verify this analysis. The positive results are given as motivation for the research to be taken to the next stage - that is, implementing the model using FPGAs.

  20. Graph Model Based Indoor Tracking

    DEFF Research Database (Denmark)

    Jensen, Christian Søndergaard; Lu, Hua; Yang, Bin

    2009-01-01

    infrastructure for different symbolic positioning technologies, e.g., Bluetooth and RFID. More specifically, the paper proposes a model of indoor space that comprises a base graph and mappings that represent the topology of indoor space at different levels. The resulting model can be used for one or several...... indoor positioning technologies. Focusing on RFID-based positioning, an RFID specific reader deployment graph model is built from the base graph model. This model is then used in several algorithms for constructing and refining trajectories from raw RFID readings. Empirical studies with implementations...

  1. LIPOMA ON THE SOLE OF FOOT: A RARE LOCATION

    Directory of Open Access Journals (Sweden)

    Ramesh Kumar

    2015-08-01

    Full Text Available Lipomas are benign soft tissue tumors that can occur at any age and frequently on the upper back, neck, shoulder and abdomen. We present a case of lipoma over sole of foot which is an uncommon location.

  2. Sole Source Aquifer Program | Drinking Water in New ...

    Science.gov (United States)

    2017-07-06

    The Safe Drinking Water Act gives EPA the authority to designate aquifers which are the sole or principal drinking water source for an area, and which, if contaminated, would create a significant hazard to public health.

  3. Metamorphic sole formation, emplacement and blueschist overprint: early obduction dynamics witnessed by W. Turkey ophiolites

    Science.gov (United States)

    Plunder, Alexis; Agard, Philippe; Chopin, Christian; Soret, Mathieu; Okay, Aral; Whitechurch, Hubert

    2016-04-01

    Western Turkey, with a >200 km long-belt of unmetamorphosed ophiolite overlying continental lithosphere is one or even the largest obducted ophiolite on Earth and therefore a key example to study obduction and early subduction dynamics. All Western Turkish ophiolite fragments are considered as part of the same Neotethyan branch resulting of a long-lived continental subduction (or underthrusting). Synchronous (ca. ~ 93 Ma) metamorphic sole formation and preservation at the base of most of the Turkish ophiolite fragments support this single event and place a strong constraint on the age of subduction initiation. Metamorphic soles are indeed generally considered to have formed during the early and hot subduction zone at 25 ± 10 km depths and welded to the overriding oceanic lithosphere. In Western Turkey however (as for most places worldwide) a systematic study of the pressure-temperature conditions with modern thermobarometric tools is generally lacking, and fundamental mechanisms of formation or accretion to the upper plate are poorly (if at all) constrained. We herein reappraise Western Turkish metamorphic soles focusing on the following points and issues: (i) detailed structures of metamorphic sole and other subduction derived units, petrological evolution and refined pressure-temperature conditions; peak pressure-temperature conditions of metamorphic sole were estimated using garnet, clinopyroxene, amphibole and plagioclase as the peak paragenesis at 10.5 ± 2 kbar and 800 ± 50°C based on pseudosections using the Theriak/Domino package (ii) the rather unique (and enigmatic) blueschist facies overprint found in places was investigated in terms of structural position and pressure-temperature conditions. Conditions of overprint were estimated around 12 kbar and 425 °C from the presence of glaucophane, lawsonite, jadeite and garnet overgrowing the amphibolite-facies assemblage. This field-based study provides clues to mechanisms of metamorphic sole underplating

  4. SOLE: Applying Semantics and Social Web to Support Technology Enhanced Learning in Software Engineering

    Science.gov (United States)

    Colomo-Palacios, Ricardo; Jiménez-López, Diego; García-Crespo, Ángel; Blanco-Iglesias, Borja

    eLearning educative processes are a challenge for educative institutions and education professionals. In an environment in which learning resources are being produced, catalogued and stored using innovative ways, SOLE provides a platform in which exam questions can be produced supported by Web 2.0 tools, catalogued and labeled via semantic web and stored and distributed using eLearning standards. This paper presents, SOLE, a social network of exam questions sharing particularized for Software Engineering domain, based on semantics and built using semantic web and eLearning standards, such as IMS Question and Test Interoperability specification 2.1.

  5. A marked bounding box method for image data reduction and reconstruction of sole patterns

    Science.gov (United States)

    Wang, Xingyue; Wu, Jianhua; Zhao, Qingmin; Cheng, Jian; Zhu, Yican

    2012-01-01

    A novel and efficient method called marked bounding box method based on marching cubes is presented for the point cloud data reduction of sole patterns. This method is characterized in that each bounding box is marked with an index during the process of data reduction and later for use of data reconstruction. The data reconstruction is implemented from the simplified data set by using triangular meshes, the indices being used to search the nearest points from adjacent bounding boxes. Afterwards, the normal vectors are estimated to determine the strength and direction of the surface reflected light. The proposed method is used in a sole pattern classification and query system which uses OpenGL under Visual C++ to render the image of sole patterns. Digital results are given to demonstrate the efficiency and novelty of our method. Finally, conclusion and discussions are made.

  6. Model-based consensus

    NARCIS (Netherlands)

    Boumans, Marcel

    2014-01-01

    The aim of the rational-consensus method is to produce “rational consensus”, that is, “mathematical aggregation”, by weighing the performance of each expert on the basis of his or her knowledge and ability to judge relevant uncertainties. The measurement of the performance of the experts is based on

  7. Model-based consensus

    NARCIS (Netherlands)

    M. Boumans

    2014-01-01

    The aim of the rational-consensus method is to produce "rational consensus", that is, "mathematical aggregation", by weighing the performance of each expert on the basis of his or her knowledge and ability to judge relevant uncertainties. The measurement of the performance of the experts is based on

  8. Graph Model Based Indoor Tracking

    DEFF Research Database (Denmark)

    Jensen, Christian Søndergaard; Lu, Hua; Yang, Bin

    2009-01-01

    The tracking of the locations of moving objects in large indoor spaces is important, as it enables a range of applications related to, e.g., security and indoor navigation and guidance. This paper presents a graph model based approach to indoor tracking that offers a uniform data management...... infrastructure for different symbolic positioning technologies, e.g., Bluetooth and RFID. More specifically, the paper proposes a model of indoor space that comprises a base graph and mappings that represent the topology of indoor space at different levels. The resulting model can be used for one or several...... indoor positioning technologies. Focusing on RFID-based positioning, an RFID specific reader deployment graph model is built from the base graph model. This model is then used in several algorithms for constructing and refining trajectories from raw RFID readings. Empirical studies with implementations...

  9. Electrohydrodynamic flow caused by field-enhanced dissociation solely

    Science.gov (United States)

    Vasilkov, S. A.; Chirkov, V. A.; Stishkov, Yu. K.

    2017-06-01

    Electrohydrodynamic (EHD) flows emerge in dielectric liquids under the action of the Coulomb force and underlie energy-efficient techniques for heat and mass transfer. The key issue in the phenomena is the way how the net charge is created. One of the most promising, yet poorly studied charge formation mechanisms is the field-enhanced dissociation (or the Wien effect). So the paper studies an EHD flow caused solely by the effect by virtue of both experiment and computer simulation. To preclude the competing mechanism of charge formation—the injection—a new EHD system of a special design was examined. Its main feature is the use of solid insulation to create the region of the strong electric field far from the electrode metal surfaces. The experimental study used the particle image velocimetry technique to observe velocity distributions, whereas the computations were based on the complete set of electrohydrodynamic equations employing the commercial software package COMSOL Multiphysics. Spatial distributions of key quantities (including the ion concentrations, the total space charge density, and the velocity) and the acting forces were obtained in the computer simulation and were analyzed. The experimental flow structure was observed for a number of voltages up to 30 kV. The comparison of the numerical and experimental results yielded a good quantitative agreement for strong electric fields though some overshoot was observed for weak ones. The results allow concluding on the applicability of the Onsager theory of the field-enhanced dissociation in the context of EHD flows.

  10. Efficient Model-Based Exploration

    NARCIS (Netherlands)

    Wiering, M.A.; Schmidhuber, J.

    1998-01-01

    Model-Based Reinforcement Learning (MBRL) can greatly profit from using world models for estimating the consequences of selecting particular actions: an animat can construct such a model from its experiences and use it for computing rewarding behavior. We study the problem of collecting useful exper

  11. Stiffness Effects in Rocker-Soled Shoes: Biomechanical Implications

    Science.gov (United States)

    Su, Pei-Fang; Chung, Chia-Hua; Hsia, Chi-Chun; Chang, Chih-Han

    2017-01-01

    Rocker-soled shoes provide a way to reduce the possible concentration of stress, as well as change movement patterns, during gait. This study attempts to examine how plantar force and spatio-temporal variables are affected by two rocker designs, one with softer and one with denser sole materials, by comparing them with the barefoot condition and with flat-soled shoes. Eleven subjects’ gait parameters during walking and jogging were recorded. Our results showed that compared with barefoot walking, plantar forces were higher for flat shoes while lower for both types of rocker shoes, the softer-material rocker being the lowest. The plantar force of flat shoes is greater than the vertical ground reaction force, while that of both rocker shoes is much less, 13.87–30.55% body weight. However, as locomotion speed increased to jogging, for all shoe types, except at the second peak plantar force of the denser sole material rocker shoes, plantar forces were greater than for bare feet. More interestingly, because the transmission of force was faster while jogging, greater plantar force was seen in the rocker-soled shoes with softer material than with denser material; results for higher-speed shock absorption in rocker-soled shoes with softer material were thus not as good. In general, the rolling phenomena along the bottom surface of the rocker shoes, as well as an increase in the duration of simultaneous curve rolling and ankle rotation, could contribute to the reduction of plantar force for both rocker designs. The possible mechanism is the conversion of vertical kinetic energy into rotational kinetic energy. To conclude, since plantar force is related to foot-ground interface and deceleration methods, rocker-design shoes could achieve desired plantar force reduction through certain rolling phenomena, shoe-sole stiffness levels, and locomotion speeds. PMID:28046009

  12. Mars 2020 Model Based Systems Engineering Pilot

    Science.gov (United States)

    Dukes, Alexandra Marie

    2017-01-01

    The pilot study is led by the Integration Engineering group in NASA's Launch Services Program (LSP). The Integration Engineering (IE) group is responsible for managing the interfaces between the spacecraft and launch vehicle. This pilot investigates the utility of Model-Based Systems Engineering (MBSE) with respect to managing and verifying interface requirements. The main objectives of the pilot are to model several key aspects of the Mars 2020 integrated operations and interface requirements based on the design and verification artifacts from Mars Science Laboratory (MSL) and to demonstrate how MBSE could be used by LSP to gain further insight on the interface between the spacecraft and launch vehicle as well as to enhance how LSP manages the launch service. The method used to accomplish this pilot started through familiarization of SysML, MagicDraw, and the Mars 2020 and MSL systems through books, tutorials, and NASA documentation. MSL was chosen as the focus of the model since its processes and verifications translate easily to the Mars 2020 mission. The study was further focused by modeling specialized systems and processes within MSL in order to demonstrate the utility of MBSE for the rest of the mission. The systems chosen were the In-Flight Disconnect (IFD) system and the Mass Properties process. The IFD was chosen as a system of focus since it is an interface between the spacecraft and launch vehicle which can demonstrate the usefulness of MBSE from a system perspective. The Mass Properties process was chosen as a process of focus since the verifications for mass properties occur throughout the lifecycle and can demonstrate the usefulness of MBSE from a multi-discipline perspective. Several iterations of both perspectives have been modeled and evaluated. While the pilot study will continue for another 2 weeks, pros and cons of using MBSE for LSP IE have been identified. A pro of using MBSE includes an integrated view of the disciplines, requirements, and

  13. Event-Based Conceptual Modeling

    DEFF Research Database (Denmark)

    Bækgaard, Lars

    The paper demonstrates that a wide variety of event-based modeling approaches are based on special cases of the same general event concept, and that the general event concept can be used to unify the otherwise unrelated fields of information modeling and process modeling. A set of event......-based modeling approaches are analyzed and the results are used to formulate a general event concept that can be used for unifying the seemingly unrelated event concepts. Events are characterized as short-duration processes that have participants, consequences, and properties, and that may be modeled in terms...... of information structures. The general event concept can be used to guide systems analysis and design and to improve modeling approaches....

  14. Empirically Based, Agent-based models

    Directory of Open Access Journals (Sweden)

    Elinor Ostrom

    2006-12-01

    Full Text Available There is an increasing drive to combine agent-based models with empirical methods. An overview is provided of the various empirical methods that are used for different kinds of questions. Four categories of empirical approaches are identified in which agent-based models have been empirically tested: case studies, stylized facts, role-playing games, and laboratory experiments. We discuss how these different types of empirical studies can be combined. The various ways empirical techniques are used illustrate the main challenges of contemporary social sciences: (1 how to develop models that are generalizable and still applicable in specific cases, and (2 how to scale up the processes of interactions of a few agents to interactions among many agents.

  15. Base Flow Model Validation Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The program focuses on turbulence modeling enhancements for predicting high-speed rocket base flows. A key component of the effort is the collection of high-fidelity...

  16. Ecophys.Fish perspectives on growth of juvenile soles, Solea solea and Solea senegalensis, in the Tagus estuary, Portugal

    Science.gov (United States)

    Fonseca, Vanessa F.; Neill, William H.; Miller, John M.; Cabral, Henrique N.

    2010-07-01

    Ecophys.Fish, an ecophysiological framework to simulate fish growth in time-varying environments, was parameterized for two sole species, Solea solea (Linnaeus, 1758) and Solea senegalensis Kaup, 1858. The model gave reliable predictions of soles' growth and metabolic rates from published data under controlled environments. Differences in model parameters reflected specie's different environmental optima and were in accordance with their distributional range — northern range of S. solea and a southern range of S. senegalensis. Field application of this model to resolve the effects of varying habitat conditions on juvenile soles' growth in the Tagus estuary (Portugal), during the spring-summer period from 2003 to 2006, highlighted spatial and temporal differences in soles' metabolic scope for growth and estimated growth rates. Higher growth estimates were obtained for S. solea and S. senegalensis in Vila Franca de Xira during 2006, and for S. senegalensis in Alcochete during 2003, 2004 and 2006, and were fairly well explained by natural variation in abiotic conditions. Overall, the Ecophys.Fish model gave accurate field predictions of each sole species' growth rate and proved to be a useful tool for monitoring and assessment of habitat quality for juvenile sole.

  17. Event-Based Conceptual Modeling

    DEFF Research Database (Denmark)

    Bækgaard, Lars

    2009-01-01

    The purpose of the paper is to obtain insight into and provide practical advice for event-based conceptual modeling. We analyze a set of event concepts and use the results to formulate a conceptual event model that is used to identify guidelines for creation of dynamic process models and static...... information models. We characterize events as short-duration processes that have participants, consequences, and properties, and that may be modeled in terms of information structures. The conceptual event model is used to characterize a variety of event concepts and it is used to illustrate how events can...... be used to integrate dynamic modeling of processes and static modeling of information structures. The results are unique in the sense that no other general event concept has been used to unify a similar broad variety of seemingly incompatible event concepts. The general event concept can be used...

  18. Event-Based Activity Modeling

    DEFF Research Database (Denmark)

    Bækgaard, Lars

    2004-01-01

    We present and discuss a modeling approach that supports event-based modeling of information and activity in information systems. Interacting human actors and IT-actors may carry out such activity. We use events to create meaningful relations between information structures and the related activit...

  19. Sustainable Production of Ammonia solely using Solar Power, Water, and Air

    OpenAIRE

    Call, Friedemann; Felinks, Jan; Lange, Matthias; Sattler, Christian

    2015-01-01

    A process is proposed capable to produce ammonia solely from sun, water and air and therewith promising to replace the million-ton consumption of natural gas with solar production of hydrogen and nitrogen. While several routes for solar hydrogen production were important research subjects for decades, an innovative and sustainable nitrogen generation is still missing. Our approach to produce nitrogen is based on a novel air separation: a thermochemical cycle based on ...

  20. Degloved foot sole successfully reconstructed with split thickness skin grafts

    NARCIS (Netherlands)

    Janssens, Loes; Holtslag, Herman R.; Schellekens, Pascal P A; Leenen, Luke P H

    2015-01-01

    Introduction The current opinion is that split thickness skin grafts are not suitable to reconstruct a degloved foot sole. The tissue is too fragile to carry full bodyweight; and therefore, stress lesions frequently occur. The treatment of choice is the reuse of the avulsed skin whenever possible,

  1. Children's Adjustment in Joint and Sole Physical Custody Families.

    Science.gov (United States)

    Kline, Marsha; And Others

    1989-01-01

    Examined patterns of custody and their relationship to the behavioral-emotional and social adjustment of 93 children of 3-14 years of age. Found no evidence that joint physical custody arrangements differ from sole physical custody arrangements with regard to postdivorce child adjustment. (RH)

  2. Recognition and Accountability: Sole Parent Postgraduates in University Conditions

    Science.gov (United States)

    Hook, Genine A.

    2015-01-01

    This paper aims to examine some of ways sole parents sought recognition as postgraduate students in Australian universities. Judith Butler's theory of recognition notes that recognition is always partial and any account we give of ourselves must be given to another. Participants articulated that supervisors were critical in the process of…

  3. Acute meningoencephalitis as the sole manifestation of Q fever.

    Science.gov (United States)

    Guerrero, M; Gutierrez, J; Carnero, C; Gonzalez-Maldonado, R; Maroto, C

    1993-01-01

    The case of a 25-year old man who presented with meningoencephalitis as the sole clinical manifestation of Q fever is described. Serological studies revealed the presence of IgM and IgG antibodies to Coxiella burnetii. The patient responded favourably to a ten-day course of i.v. ceftriaxone and was discharged without any neurological sequelae.

  4. Stocking density-dependent growth of Dover sole (Solea solea)

    NARCIS (Netherlands)

    Schram, E.; Heul, van der J.W.; Kamstra, A.; Verdegem, M.C.J.

    2006-01-01

    Dover sole were reared at 6 different stocking densities between 0.56 and 12.6 kg/m2 with duplicate tanks for each treatment. The experiment lasted for 55 days. Water quality effects on growth were minimised by making the flow rate per tank proportional to the feeding load. Individual initial and

  5. ELECTROCHEMICAL TECHNOLOGIES FOR OBTAINING MOULDS FOR SOLES OF SHOES

    Directory of Open Access Journals (Sweden)

    Cornelia LUCA

    2013-05-01

    Full Text Available The paper presents contributions in the designing of some electrochemical technologiesfor the manufacturing of the moulds used in the footwear soles obtaining. There are presented a fewmethods for the moulds obtaining, using electro-deposit processes. There are presented thetechnological phases of the obtaining process of the electrolytes and electrodes preparing and thetechnological stages of the moulds manufacturing.

  6. Selecting Sole: breeding programs for natural - mating populations

    NARCIS (Netherlands)

    Blonk, R.J.W.

    2010-01-01

    The aim of this thesis was to design a breeding program for increased productivity of farmed common sole, Solea solea, 1) using natural mating in groups to obtain offspring and 2) using present farm infrastructures as much as possible. Parental allocation with DNA marker data on offspring from

  7. Modelling Gesture Based Ubiquitous Applications

    CERN Document Server

    Zacharia, Kurien; Varghese, Surekha Mariam

    2011-01-01

    A cost effective, gesture based modelling technique called Virtual Interactive Prototyping (VIP) is described in this paper. Prototyping is implemented by projecting a virtual model of the equipment to be prototyped. Users can interact with the virtual model like the original working equipment. For capturing and tracking the user interactions with the model image and sound processing techniques are used. VIP is a flexible and interactive prototyping method that has much application in ubiquitous computing environments. Different commercial as well as socio-economic applications and extension to interactive advertising of VIP are also discussed.

  8. Agent Based Multiviews Requirements Model

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Based on the current researches of viewpoints oriented requirements engineering and intelligent agent, we present the concept of viewpoint agent and its abstract model based on a meta-language for multiviews requirements engineering. It provided a basis for consistency checking and integration of different viewpoint requirements, at the same time, these checking and integration works can automatically realized in virtue of intelligent agent's autonomy, proactiveness and social ability. Finally, we introduce the practical application of the model by the case study of data flow diagram.

  9. Size selectivity of sole gill nets fished in the North Sea

    DEFF Research Database (Denmark)

    Madsen, Niels; Holst, René; Wileman, D.

    1999-01-01

    , plaice and cod for each setting of the gear. It was found that a hi-normal form for the selection curve gave the best fits. Mean selection curves were then estimated by combining sets using a model of between-set variation. The ratio between length of maximum retention and mesh size was estimated to be 3.......28 for sole, 2.60 for plaice and 4.56 for cod. Selection curves were also fitted to the catch data pooled over all sets. The model deviance for the sole and plaice data indicated lack of lit when pooling the catch data. (C) 1999 Elsevier Science B.V. All rights reserved....

  10. TOWARDS A SYSTEM DYNAMICS MODELING METHOD BASED ON DEMATEL

    Directory of Open Access Journals (Sweden)

    Fadwa Chaker

    2015-05-01

    Full Text Available If System Dynamics (SD models are constructed based solely on decision makers' mental models and understanding of the context subject to study, then the resulting systems must necessarily bear some degree of deficiency due to the subjective, limited, and internally inconsistent mental models which led to the conception of these systems. As such, a systematic method for constructing SD models could be essentially helpful in overcoming the biases dictated by the human mind's limited understanding and conceptualization of complex systems. This paper proposes a novel combined method to support SD model construction. The classical Decision Making Trial and Evaluation Laboratory (DEMATEL technique is used to define causal relationships among variables of a system, and to construct the corresponding Impact Relation Maps (IRMs. The novelty of this paper stems from the use of the resulting total influence matrix to derive the system dynamic's Causal Loop Diagram (CLD and then define variable weights in the stock-flow chart equations. This new method allows to overcome the subjectivity bias of SD modeling while projecting DEMATEL in a more dynamic simulation environment, which could significantly improve the strategic choices made by analysts and policy makers.

  11. Mechanical behaviour of the Oman metamorphic sole: rheology of amphibolites at lower crustal conditions during subduction initiation

    Science.gov (United States)

    Soret, Mathieu; Agard, Philippe; Ildefonse, Benoît; Dubacq, Benoît; Prigent, Cécile; Yamato, Philippe

    2017-04-01

    Amphibolites are commonly found in the middle to lower continental crust and along oceanic transform faults and detachments. Amphibolites are also the main component of metamorphic soles beneath highly strained peridotites at the base of large-scale ophiolites as exemplified in Oman. Metamorphic soles are crustal slivers stripped from the slab during early subduction and underplated below the upper plate (future ophiolite) mantle when the subduction interface is still young and warm (i.e. during the first million years -My- of intra-oceanic subduction). Understanding the rheological behaviour of amphibolitic rocks is therefore of major interest to model and quantify deformation and strain localisation in varied geodynamical environments. This contribution focuses on the deformation mechanisms of amphibole through a microstructural and petrological study of garnet-bearing and garnet-free clinopyroxene-bearing amphibolites, using EBSD analysis. The first aim is to test the influence of progres- sive changes in PT conditions during deformation and of the appearance/disappearance of anhydrous minerals (plagioclase, clinopyroxene and garnet) on the mechanical behaviour of mafic amphibolites. The second aim is to track deformation mechanisms during early subduction, through the study of these metamorphosed oceanic rocks, commonly 10-100 m thick, which range from high- to low-grade away from the contact with the peridotites (i.e. from 800 ± 100˚C - 0.9 ± 0.2 GPa to 500 ± 100˚C - 0.5 ± 0.1 GPa) and are essentially mafic at the top). Our study points out the existence of two major steps of deformation in the high-temperature amphibolite slices of the metamorphic soles during the early subdduction dynamics. These two steps witness important mechanical coupling and progressive strain localization at plate interface under cooling and hydrated conditions after subduction initiation. During the accretion of the first slice of metamorphic sole at 850 ± 50˚C (the garnet

  12. Model-Based Security Testing

    CERN Document Server

    Schieferdecker, Ina; Schneider, Martin; 10.4204/EPTCS.80.1

    2012-01-01

    Security testing aims at validating software system requirements related to security properties like confidentiality, integrity, authentication, authorization, availability, and non-repudiation. Although security testing techniques are available for many years, there has been little approaches that allow for specification of test cases at a higher level of abstraction, for enabling guidance on test identification and specification as well as for automated test generation. Model-based security testing (MBST) is a relatively new field and especially dedicated to the systematic and efficient specification and documentation of security test objectives, security test cases and test suites, as well as to their automated or semi-automated generation. In particular, the combination of security modelling and test generation approaches is still a challenge in research and of high interest for industrial applications. MBST includes e.g. security functional testing, model-based fuzzing, risk- and threat-oriented testing,...

  13. Kernel model-based diagnosis

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    The methods for computing the kemel consistency-based diagnoses and the kernel abductive diagnoses are only suited for the situation where part of the fault behavioral modes of the components are known. The characterization of the kernel model-based diagnosis based on the general causal theory is proposed, which can break through the limitation of the above methods when all behavioral modes of each component are known. Using this method, when observation subsets deduced logically are respectively assigned to the empty or the whole observation set, the kernel consistency-based diagnoses and the kernel abductive diagnoses can deal with all situations. The direct relationship between this diagnostic procedure and the prime implicants/implicates is proved, thus linking theoretical result with implementation.

  14. Model-based tomographic reconstruction

    Science.gov (United States)

    Chambers, David H; Lehman, Sean K; Goodman, Dennis M

    2012-06-26

    A model-based approach to estimating wall positions for a building is developed and tested using simulated data. It borrows two techniques from geophysical inversion problems, layer stripping and stacking, and combines them with a model-based estimation algorithm that minimizes the mean-square error between the predicted signal and the data. The technique is designed to process multiple looks from an ultra wideband radar array. The processed signal is time-gated and each section processed to detect the presence of a wall and estimate its position, thickness, and material parameters. The floor plan of a building is determined by moving the array around the outside of the building. In this paper we describe how the stacking and layer stripping algorithms are combined and show the results from a simple numerical example of three parallel walls.

  15. An analysis of the socio-demographic characteristics of sole registered births and infant deaths.

    Science.gov (United States)

    Messer, Julie

    2011-01-01

    Differences in birth characteristics and infant mortality rates by marital status and birth registration type reflect complex underlying factors. In particular, births registered solely by the mother are seen as a disadvantaged group. This article analyses the socio-demographic characteristics of births by registration type and parents' marital status and explores these differences for health outcomes. Birth notifications data from the NHS Numbers for Babies system was linked to birth registration data held by the Office for National Statistics (ONS) for births occurring in 2007 and 2008 in England and Wales. This dataset was further linked to death registration data to identify infants who died before their first birthday.Regression analysis was used to compare factors and health outcomes across marital and registration status groups. Regression models were calculated to determine the main risk factors for poor outcomes. The registration groups differed in the age of the mother at birth, the proportion of young mothers, ethnic group distribution and measures of deprived circumstances. The joint registered-different address and sole registered groups were similar in the proportion of young mothers and the deprivation indices. The groups also differed in the proportion of low birthweight and premature babies. The joint registered-different address and sole registered groups both had higher percentages of 'small for gestational age' babies compared with the within-marriage and joint registered-same address groups. The stillbirth rate was highest in the sole registered group. Both the joint registered-different address and sole registered groups had higher infant mortality rates compared with the within-marriage and joint registered-same address groups. Multivariate analysis indicated that low birthweight was a key factor in infant mortality. Births registered solely by the mother were found to be a disadvantaged group but were also similar to the joint

  16. Model-Based Security Testing

    Directory of Open Access Journals (Sweden)

    Ina Schieferdecker

    2012-02-01

    Full Text Available Security testing aims at validating software system requirements related to security properties like confidentiality, integrity, authentication, authorization, availability, and non-repudiation. Although security testing techniques are available for many years, there has been little approaches that allow for specification of test cases at a higher level of abstraction, for enabling guidance on test identification and specification as well as for automated test generation. Model-based security testing (MBST is a relatively new field and especially dedicated to the systematic and efficient specification and documentation of security test objectives, security test cases and test suites, as well as to their automated or semi-automated generation. In particular, the combination of security modelling and test generation approaches is still a challenge in research and of high interest for industrial applications. MBST includes e.g. security functional testing, model-based fuzzing, risk- and threat-oriented testing, and the usage of security test patterns. This paper provides a survey on MBST techniques and the related models as well as samples of new methods and tools that are under development in the European ITEA2-project DIAMONDS.

  17. Manifestation of pernicious anaemia as hyperpigmentation of palms and soles

    Directory of Open Access Journals (Sweden)

    Srinivas Vaddadi

    2016-05-01

    Full Text Available Vitamin B12 deficiency produces various manifestations involving CNS, heart, skin, blood and female reproductive systems. It is seen most commonly in the older individuals, malabsorptive states and #8201;(>60% of all cases and vegetarians. Pernicious anaemia may be confused to Addison's disease as both may present with similar clinical features. Hereby we report a case of pernicious anaemia presenting with dermatological manifestation in the form of deep pigmentation of both palms of and both soles respectively, cortisol levels normal so Addition's disease ruled out. [Int J Res Med Sci 2016; 4(5.000: 1746-1748

  18. Eclissi! Quando Sole e Luna danno spettacolo in cielo

    CERN Document Server

    Bastoni, Marco

    2012-01-01

    Le eclissi di Sole e di Luna sono fra gli spettacoli più avvincenti della Natura; questo libro è una guida completa alla loro osservazione e spiega come cercare, vivere e fotografare questi eventi senza necessariamente essere astrofili esperti. Cosa posso osservare durante un’eclisse? Da dove? E quando? Un’accurata selezione delle 10 eclissi imperdibili da qui al 2050 chiude l’opera, aiutando il lettore nella pianificazione delle osservazioni. Preparate i bagagli, guardate l’eclisse e lasciatevi emozionare!

  19. [Fibromatosis plantaris Ledderhose (Dupuytren's contracture of the foot sole].

    Science.gov (United States)

    Villiger, K J

    1982-05-01

    Fibromatosis plantaris, also called Ledderhose disease, is presented on the basis of the limited literature available. The possible causes are mentioned. Two cases are reported of patients suffering from fibromatosis palmaris (Dupuytren) on both hands and fibromatosis plantaris (Ledderhose) on both feet simultaneously. It is suggested that more attention be paid to examination of the soles of the feet, especially after a period of immobilization and plaster fixation of the shank. On diagnosis of Ledderhose disease, surgery should be performed before the often irreversible deformation of the toes develops.

  20. Simultaneous sinus lift and implantation using platelet-rich fibrin as sole grafting material.

    Science.gov (United States)

    Jeong, Seung-Mi; Lee, Chun-Ui; Son, Jeong-Seog; Oh, Ji-Hyeon; Fang, Yiqin; Choi, Byung-Ho

    2014-09-01

    Recently, several authors have shown that simultaneous sinus lift and implantation using autologous platelet-rich fibrin as the sole filling material is a reliable procedure promoting bone augmentation in the maxillary sinus. The aim of this study was to examine the effect of simultaneous sinus lift and implantation using platelet-rich fibrin as the sole grafting material on bone formation in a canine sinus model. An implant was placed after sinus membrane elevation in the maxillary sinus of six adult female mongrel dogs. The resulting space between the membrane and sinus floor was filled with autologous platelet-rich fibrin retrieved from each dog. The implants were left in place for six months. Bone tissue was seen at the lower part of the implants introduced into the sinus cavity. The height of the newly formed bone around the implants ranged from 0 mm to 4.9 mm (mean; 2.6 ± 2.0 mm) on the buccal side and from 0 mm to 4.2 mm (mean; 1.3 ± 1.8 mm) on the palatal side. The findings from this study suggest that simultaneous sinus lift and implantation using platelet-rich fibrin as sole grafting material is not a predictable and reproducible procedure, especially with respect to the bone formation around the implants in the sinus cavity.

  1. Design optimization of thin-film/wafer-based tandem junction solar cells using analytical modeling

    Science.gov (United States)

    Davidson, Lauren; Toor, Fatima

    2016-03-01

    Several research groups are developing solar cells of varying designs and materials that are high efficiency as well as cost competitive with the single junction silicon (Si) solar cells commercially produced today. One of these solar cell designs is a tandem junction solar cell comprised of perovskite (CH3NH3PbI3) and silicon (Si). Loper et al.1 was able to create a 13.4% efficient tandem cell using a perovskite top cell and a Si bottom cell, and researchers are confident that the perovskite/Si tandem cell can be optimized in order to reach higher efficiencies without introducing expensive manufacturing processes. However, there are currently no commercially available software capable of modeling a tandem cell that is based on a thin-film based bottom cell and a wafer-based top cell. While PC1D2 and SCAPS3 are able to model tandem cells comprised solely of thin-film absorbers or solely of wafer-based absorbers, they result in convergence errors if a thin-film/wafer-based tandem cell, such as the perovskite/ Si cell, is modeled. The Matlab-based analytical model presented in this work is capable of modeling a thin-film/wafer-based tandem solar cell. The model allows a user to adjust the top and bottom cell parameters, such as reflectivity, material bandgaps, donor and acceptor densities, and material thicknesses, in order to optimize the short circuit current, open circuit voltage, and quantum efficiency of the tandem solar cell. Using the Matlab-based analytical model, we were able optimize a perovskite/Si tandem cell with an efficiency greater than 30%.

  2. Crowdsourcing Based 3d Modeling

    Science.gov (United States)

    Somogyi, A.; Barsi, A.; Molnar, B.; Lovas, T.

    2016-06-01

    Web-based photo albums that support organizing and viewing the users' images are widely used. These services provide a convenient solution for storing, editing and sharing images. In many cases, the users attach geotags to the images in order to enable using them e.g. in location based applications on social networks. Our paper discusses a procedure that collects open access images from a site frequently visited by tourists. Geotagged pictures showing the image of a sight or tourist attraction are selected and processed in photogrammetric processing software that produces the 3D model of the captured object. For the particular investigation we selected three attractions in Budapest. To assess the geometrical accuracy, we used laser scanner and DSLR as well as smart phone photography to derive reference values to enable verifying the spatial model obtained from the web-album images. The investigation shows how detailed and accurate models could be derived applying photogrammetric processing software, simply by using images of the community, without visiting the site.

  3. An Agent Based Classification Model

    CERN Document Server

    Gu, Feng; Greensmith, Julie

    2009-01-01

    The major function of this model is to access the UCI Wisconsin Breast Can- cer data-set[1] and classify the data items into two categories, which are normal and anomalous. This kind of classifi cation can be referred as anomaly detection, which discriminates anomalous behaviour from normal behaviour in computer systems. One popular solution for anomaly detection is Artifi cial Immune Sys- tems (AIS). AIS are adaptive systems inspired by theoretical immunology and observed immune functions, principles and models which are applied to prob- lem solving. The Dendritic Cell Algorithm (DCA)[2] is an AIS algorithm that is developed specifi cally for anomaly detection. It has been successfully applied to intrusion detection in computer security. It is believed that agent-based mod- elling is an ideal approach for implementing AIS, as intelligent agents could be the perfect representations of immune entities in AIS. This model evaluates the feasibility of re-implementing the DCA in an agent-based simulation environ- ...

  4. Single Locus Maintains Large Variation of Sex Reversal in Half-Smooth Tongue Sole (Cynoglossus semilaevis).

    Science.gov (United States)

    Jiang, Li; Li, Hengde

    2017-02-09

    Sex determination is a fundamental biological process for individual sex development and population sex ratios. However, for some species, the primary sex might be altered during development, and individuals can develop into the opposite sex. Sex reversal may happen in insects, reptiles, amphibians, and fishes. In half-smooth tongue sole (Cynoglossus semilaevis), some genetically female fish irreversibly reverse to pseudomales, resulting in higher costs in aquaculture owing to a lower growth rate of male fish during a 2-yr growth period. Here, we identified a locus with large controlling effect on sex reversal in the half-smooth tongue sole through genome-wide association study with high-density single nucleotide polymorphisms (SNPs). This SNP is located at the third intron of the F-box and leucine rich repeat protein 17 (FBXL17) gene on the Z chromosome, and it has two alleles, A and T. Genetic females with Z(A)W genotypes will never reverse into phenotypic males, but those with Z(T)W genotypes can sometimes undergo sex reversal. This SNP explains 82.7% of the genetic variation, or 58.4% of the phenotypic variation. Based on our results, a reproductive management program could be developed to improve the phenotypic female ratio in aquaculture, and elucidate the mechanism of sex reversal in half-smooth tongue sole. We expect that these findings will have a substantial impact on the population management in many harvested species where sex reversal occurs. Copyright © 2017 Jiang and Li.

  5. Characterization of stress coping style in Senegalese sole (Solea senegalensis) juveniles and breeders for aquaculture.

    Science.gov (United States)

    Ibarra-Zatarain, Z; Fatsini, E; Rey, S; Chereguini, O; Martin, I; Rasines, I; Alcaraz, C; Duncan, N

    2016-11-01

    The aim of this work was to characterize stress coping styles of Senegalese sole (Solea senegalensis) juveniles and breeders and to select an operational behavioural screening test (OBST) that can be used by the aquaculture industry to classify and select between behavioural phenotypes in order to improve production indicators. A total of 61 juveniles and 59 breeders were subjected to five individual behavioural tests and two grouping tests. At the end of the individual tests, all animals were blood sampled in order to measure cortisol, glucose and lactate. Three tests (restraining, new environment and confinement) characterized the stress coping style behaviour of Senegalese sole juveniles and breeders and demonstrated inter-individual consistency. Further, the tests when incorporated into a principal components analysis (PCA) (i) identified two principal axes of personality traits: 'fearfulness-reactivity' and 'activity-exploration', (ii) were representative of the physiological axis of stress coping style, and (iii) were validated by established group tests. This study proposed for the first time three individual coping style tests that reliably represented proactive and reactive personalities of Senegalese sole juveniles and breeders. In addition, the three proposed tests met some basic operational criteria (rapid testing, no special equipment and easy to apply and interpret) that could prove attractive for fish farmers to identify fish with a specific behaviour that gives advantages in the culture system and that could be used to establish selection-based breeding programmes to improve domestication and production.

  6. Single Locus Maintains Large Variation of Sex Reversal in Half-Smooth Tongue Sole (Cynoglossus semilaevis

    Directory of Open Access Journals (Sweden)

    Li Jiang

    2017-02-01

    Full Text Available Sex determination is a fundamental biological process for individual sex development and population sex ratios. However, for some species, the primary sex might be altered during development, and individuals can develop into the opposite sex. Sex reversal may happen in insects, reptiles, amphibians, and fishes. In half-smooth tongue sole (Cynoglossus semilaevis, some genetically female fish irreversibly reverse to pseudomales, resulting in higher costs in aquaculture owing to a lower growth rate of male fish during a 2-yr growth period. Here, we identified a locus with large controlling effect on sex reversal in the half-smooth tongue sole through genome-wide association study with high-density single nucleotide polymorphisms (SNPs. This SNP is located at the third intron of the F-box and leucine rich repeat protein 17 (FBXL17 gene on the Z chromosome, and it has two alleles, A and T. Genetic females with ZAW genotypes will never reverse into phenotypic males, but those with ZTW genotypes can sometimes undergo sex reversal. This SNP explains 82.7% of the genetic variation, or 58.4% of the phenotypic variation. Based on our results, a reproductive management program could be developed to improve the phenotypic female ratio in aquaculture, and elucidate the mechanism of sex reversal in half-smooth tongue sole. We expect that these findings will have a substantial impact on the population management in many harvested species where sex reversal occurs.

  7. Relational Resilience in Māori, Pacific, and European Sole Parent Families: From Theory and Research to Social Policy.

    Science.gov (United States)

    Waldegrave, Charles; King, Peter; Maniapoto, Maria; Tamasese, Taimalieutu Kiwi; Parsons, Tafaoimalo Loudeen; Sullivan, Ginny

    2016-12-01

    This study reports findings and policy recommendations from a research project that applied a relational resilience framework to a study of 60 sole parent families in New Zealand, with approximately equal numbers of Māori, Pacific, and European (White) participants. The sole parent families involved were already known to be resilient and the study focused on identifying the relationships and strategies underlying the achievement and maintenance of their resilience. The study was carried out to provide an evidence base for the development and implementation of policies and interventions to both support sole parent families who have achieved resilience and assist those who struggle to do so. The three populations shared many similarities in their pathways to becoming sole parents and the challenges they faced as sole parents. The coping strategies underlying their demonstrated resilience were also broadly similar, but the ways in which they were carried out did vary in a manner that particularly reflected cultural practices in terms of their reliance upon extended family-based support or support from outside the family. The commonalities support the appropriateness of the common conceptual framework used, whereas the differences underline the importance of developing nuanced policy responses that take into account cultural differences between the various populations to which policy initiatives are directed. © 2016 Family Process Institute.

  8. Growth kinetics and toxicity of Enterobacter cloacae grown on linear alkylbenzene sulfonate as sole carbon source.

    Science.gov (United States)

    Khleifat, Khaled M; Tarawneh, Khaled A; Ali Wedyan, Mohammad; Al-Tarawneh, Amjad A; Al Sharafa, Khalid

    2008-10-01

    A successful attempt was made to isolate linear alkylbenzene sulfonate (LAS)-degrading bacteria from soil irrigated with wastewater. The isolated bacteria were able to use LAS as sole carbon and energy source. Maximum growth rates on LAS reached only 0.27 h(-1). 16S-rRNA sequencing and fatty-acid analysis placed the bacteria in the genus Enterobacter cloacae. The growth curves of E. cloacae both in the presence of and the absence of LAS were monitored using measurements of optical density at 600 nm in two different media, nutrient broth and M9 minimal medium, and were modeled mathematically. Growth in NB fit the Riccati and Voltera models, indicating that LAS is not toxic to E. cloacae cells. However, growth of E. cloacae in LAS-containing MM fit the Riccati and Voltera models, whereas growth in LAS-free MM fit the Riccati model only. Furthermore, the kinetic data shown were modeled by Monod's, Andrew's, and Tessier's specific growth rate equations, coupled with the rate of consumption of different concentrations of LAS as sole carbon and energy source, and we determined that Andrew's model best fit these data adequately as a result of the cell-inhibitory effect.

  9. Research on BOM based composable modeling method

    NARCIS (Netherlands)

    Zhang, M.; He, Q.; Gong, J.

    2013-01-01

    Composable modeling method has been a research hotpot in the area of Modeling and Simulation for a long time. In order to increase the reuse and interoperability of BOM based model, this paper put forward a composable modeling method based on BOM, studied on the basic theory of composable modeling m

  10. Intelligent model-based OPC

    Science.gov (United States)

    Huang, W. C.; Lai, C. M.; Luo, B.; Tsai, C. K.; Chih, M. H.; Lai, C. W.; Kuo, C. C.; Liu, R. G.; Lin, H. T.

    2006-03-01

    Optical proximity correction is the technique of pre-distorting mask layouts so that the printed patterns are as close to the desired shapes as possible. For model-based optical proximity correction, a lithographic model to predict the edge position (contour) of patterns on the wafer after lithographic processing is needed. Generally, segmentation of edges is performed prior to the correction. Pattern edges are dissected into several small segments with corresponding target points. During the correction, the edges are moved back and forth from the initial drawn position, assisted by the lithographic model, to finally settle on the proper positions. When the correction converges, the intensity predicted by the model in every target points hits the model-specific threshold value. Several iterations are required to achieve the convergence and the computation time increases with the increase of the required iterations. An artificial neural network is an information-processing paradigm inspired by biological nervous systems, such as how the brain processes information. It is composed of a large number of highly interconnected processing elements (neurons) working in unison to solve specific problems. A neural network can be a powerful data-modeling tool that is able to capture and represent complex input/output relationships. The network can accurately predict the behavior of a system via the learning procedure. A radial basis function network, a variant of artificial neural network, is an efficient function approximator. In this paper, a radial basis function network was used to build a mapping from the segment characteristics to the edge shift from the drawn position. This network can provide a good initial guess for each segment that OPC has carried out. The good initial guess reduces the required iterations. Consequently, cycle time can be shortened effectively. The optimization of the radial basis function network for this system was practiced by genetic algorithm

  11. Lyme disease: sudden hearing loss as the sole presentation.

    Science.gov (United States)

    Espiney Amaro, C; Montalvão, P; Huins, C; Saraiva, J

    2015-02-01

    Lyme disease is an uncommon tick-borne multisystemic infection caused by Borrelia burgdorferi. The most common clinical manifestation is erythema migrans. In this report, a very unusual presentation of this condition is described, in which sudden onset sensorineural hearing loss was the sole presenting symptom. Case report and review of English-language literature. A patient presented with sensorineural hearing loss, with no other symptoms or signs. Acute Lyme infection was detected by laboratory tests. Magnetic resonance imaging showed signs of labyrinthitis of the same inner ear. After hyperbaric oxygen and systemic antibiotic treatment, the patient showed total hearing recovery, and magnetic resonance imaging showed complete resolution of the labyrinthitis. To our knowledge, this is the first reported case of Lyme disease presenting only with sensorineural hearing loss. Borreliosis should be considered as an aetiological factor in sensorineural hearing loss. Adequate treatment may provide total recovery and prevent more severe forms of Lyme disease.

  12. Optimal pricing decision model based on activity-based costing

    Institute of Scientific and Technical Information of China (English)

    王福胜; 常庆芳

    2003-01-01

    In order to find out the applicability of the optimal pricing decision model based on conventional costbehavior model after activity-based costing has given strong shock to the conventional cost behavior model andits assumptions, detailed analyses have been made using the activity-based cost behavior and cost-volume-profitanalysis model, and it is concluded from these analyses that the theory behind the construction of optimal pri-cing decision model is still tenable under activity-based costing, but the conventional optimal pricing decisionmodel must be modified as appropriate to the activity-based costing based cost behavior model and cost-volume-profit analysis model, and an optimal pricing decision model is really a product pricing decision model construc-ted by following the economic principle of maximizing profit.

  13. Differential geometry based multiscale models.

    Science.gov (United States)

    Wei, Guo-Wei

    2010-08-01

    Large chemical and biological systems such as fuel cells, ion channels, molecular motors, and viruses are of great importance to the scientific community and public health. Typically, these complex systems in conjunction with their aquatic environment pose a fabulous challenge to theoretical description, simulation, and prediction. In this work, we propose a differential geometry based multiscale paradigm to model complex macromolecular systems, and to put macroscopic and microscopic descriptions on an equal footing. In our approach, the differential geometry theory of surfaces and geometric measure theory are employed as a natural means to couple the macroscopic continuum mechanical description of the aquatic environment with the microscopic discrete atomistic description of the macromolecule. Multiscale free energy functionals, or multiscale action functionals are constructed as a unified framework to derive the governing equations for the dynamics of different scales and different descriptions. Two types of aqueous macromolecular complexes, ones that are near equilibrium and others that are far from equilibrium, are considered in our formulations. We show that generalized Navier-Stokes equations for the fluid dynamics, generalized Poisson equations or generalized Poisson-Boltzmann equations for electrostatic interactions, and Newton's equation for the molecular dynamics can be derived by the least action principle. These equations are coupled through the continuum-discrete interface whose dynamics is governed by potential driven geometric flows. Comparison is given to classical descriptions of the fluid and electrostatic interactions without geometric flow based micro-macro interfaces. The detailed balance of forces is emphasized in the present work. We further extend the proposed multiscale paradigm to micro-macro analysis of electrohydrodynamics, electrophoresis, fuel cells, and ion channels. We derive generalized Poisson-Nernst-Planck equations that are

  14. Calibration and Finite Element Implementation of an Energy-Based Material Model for Shape Memory Alloys

    Science.gov (United States)

    Junker, Philipp; Hackl, Klaus

    2016-06-01

    Numerical simulations are a powerful tool to analyze the complex thermo-mechanically coupled material behavior of shape memory alloys during product engineering. The benefit of the simulations strongly depends on the quality of the underlying material model. In this contribution, we discuss a variational approach which is based solely on energetic considerations and demonstrate that unique calibration of such a model is sufficient to predict the material behavior at varying ambient temperature. In the beginning, we recall the necessary equations of the material model and explain the fundamental idea. Afterwards, we focus on the numerical implementation and provide all information that is needed for programing. Then, we show two different ways to calibrate the model and discuss the results. Furthermore, we show how this model is used during real-life industrial product engineering.

  15. Calibration and Finite Element Implementation of an Energy-Based Material Model for Shape Memory Alloys

    Science.gov (United States)

    Junker, Philipp; Hackl, Klaus

    2016-09-01

    Numerical simulations are a powerful tool to analyze the complex thermo-mechanically coupled material behavior of shape memory alloys during product engineering. The benefit of the simulations strongly depends on the quality of the underlying material model. In this contribution, we discuss a variational approach which is based solely on energetic considerations and demonstrate that unique calibration of such a model is sufficient to predict the material behavior at varying ambient temperature. In the beginning, we recall the necessary equations of the material model and explain the fundamental idea. Afterwards, we focus on the numerical implementation and provide all information that is needed for programing. Then, we show two different ways to calibrate the model and discuss the results. Furthermore, we show how this model is used during real-life industrial product engineering.

  16. Developing Empirically Based Models of Practice.

    Science.gov (United States)

    Blythe, Betty J.; Briar, Scott

    1985-01-01

    Over the last decade emphasis has shifted from theoretically based models of practice to empirically based models whose elements are derived from clinical research. These models are defined and a developing model of practice through the use of single-case methodology is examined. Potential impediments to this new role are identified. (Author/BL)

  17. Guide to APA-Based Models

    Science.gov (United States)

    Robins, Robert E.; Delisi, Donald P.

    2008-01-01

    In Robins and Delisi (2008), a linear decay model, a new IGE model by Sarpkaya (2006), and a series of APA-Based models were scored using data from three airports. This report is a guide to the APA-based models.

  18. Proceedings Tenth Workshop on Model Based Testing

    OpenAIRE

    Pakulin, Nikolay; Petrenko, Alexander K.; Schlingloff, Bernd-Holger

    2015-01-01

    The workshop is devoted to model-based testing of both software and hardware. Model-based testing uses models describing the required behavior of the system under consideration to guide such efforts as test selection and test results evaluation. Testing validates the real system behavior against models and checks that the implementation conforms to them, but is capable also to find errors in the models themselves. The intent of this workshop is to bring together researchers and users of model...

  19. Product Modelling for Model-Based Maintenance

    NARCIS (Netherlands)

    Houten, van F.J.A.M.; Tomiyama, T.; Salomons, O.W.

    1998-01-01

    The paper describes the fundamental concepts of maintenance and the role that information technology can play in the support of maintenance activities. Function-Behaviour-State modelling is used to describe faults and deterioration of mechanisms in terms of user perception and measurable quantities.

  20. Observation-Based Modeling for Model-Based Testing

    NARCIS (Netherlands)

    Kanstrén, T.; Piel, E.; Gross, H.-G.

    2009-01-01

    One of the single most important reasons that modeling and modelbased testing are not yet common practice in industry is the perceived difficulty of making the models up to the level of detail and quality required for their automated processing. Models unleash their full potential only through suffi

  1. Observation-Based Modeling for Model-Based Testing

    NARCIS (Netherlands)

    Kanstrén, T.; Piel, E.; Gross, H.-G.

    2009-01-01

    One of the single most important reasons that modeling and modelbased testing are not yet common practice in industry is the perceived difficulty of making the models up to the level of detail and quality required for their automated processing. Models unleash their full potential only through

  2. Return of feature-based cost modeling

    Science.gov (United States)

    Creese, Robert C.; Patrawala, Taher B.

    1998-10-01

    Feature Based Cost Modeling is thought of as a relative new approach to cost modeling, but feature based cost modeling had considerable development in the 1950's. Considerable work was published in the 1950's by Boeing on cost for various casting processes--sand casting, die casting, investment casting and permanent mold casting--as a function of a single casting feature, casting volume. Additional approaches to feature based cost modeling have been made, and this work is a review of previous works and a proposed integrated model to feature based cost modeling.

  3. gis-based hydrological model based hydrological model upstream ...

    African Journals Online (AJOL)

    eobe

    Metrological Agency (NIMET) and Jebba Hydroelectric ... cycle by SWAT is based on the water balance equation: = + (. − ... The estimation of the base flow is done using Equation. 5. = . ( ..... Acetic Acid”, Nigerian Journal of Tecnology, Vol. 32,.

  4. Sole-Source Lighting for Controlled-Environment Agriculture

    Science.gov (United States)

    Mitchell.Cary; Stutte, Gary W.

    2015-01-01

    Since plants on Earth evolved under broad-spectrum solar radiation, anytime they are grown exclusively under electric lighting that does not contain all wavelengths in similar proportion to those in sunlight, plant appearance and size could be uniquely different. Nevertheless, plants have been grown for decades under fluorescent (FL) (1) + incandescent (IN) (2) lamps as a sole source of lighting (SSL), and researchers have become comfortable that, in certain proportions of FL + IN for a given species, plants can appear "normal" relative to their growth outdoors. The problem with using such traditional SSLs for commercial production typically is short lamp lifespans and not obtaining enough photosynthetically active radiation (PAR, 400-700 nm) when desired. These limitations led to supplementation of FL + IN lamp outputs with longer-lived, high-intensity discharge (HID) lamps in growth chambers (3). As researchers became comfortable that mixes of orange-biased high-pressure sodium (HPS) and blue-biased metal halide (MH) HIDs together also could give normal plant growth at higher intensities, growth chambers and phytotrons subsequently were equipped mainly with HID lamps, with their intense thermal output filtered out by ventilated light caps or thermal-controlled water barriers. For the most part, IN and HID lamps have found a home in commercial protected horticulture, usually for night-break photoperiod lighting (IN) or for seasonal supplemental lighting (mostly HPS) in greenhouses. However, lack of economically viable options for SSL have held back aspects of year-round indoor agriculture from taking off commercially.

  5. Extensions in model-based system analysis

    OpenAIRE

    Graham, Matthew R.

    2007-01-01

    Model-based system analysis techniques provide a means for determining desired system performance prior to actual implementation. In addition to specifying desired performance, model-based analysis techniques require mathematical descriptions that characterize relevant behavior of the system. The developments of this dissertation give ex. tended formulations for control- relevant model estimation as well as model-based analysis conditions for performance requirements specified as frequency do...

  6. Trace-Based Code Generation for Model-Based Testing

    NARCIS (Netherlands)

    Kanstrén, T.; Piel, E.; Gross, H.-G.

    2009-01-01

    Paper Submitted for review at the Eighth International Conference on Generative Programming and Component Engineering. Model-based testing can be a powerful means to generate test cases for the system under test. However, creating a useful model for model-based testing requires expertise in the (fo

  7. Trace-Based Code Generation for Model-Based Testing

    NARCIS (Netherlands)

    Kanstrén, T.; Piel, E.; Gross, H.-G.

    2009-01-01

    Paper Submitted for review at the Eighth International Conference on Generative Programming and Component Engineering. Model-based testing can be a powerful means to generate test cases for the system under test. However, creating a useful model for model-based testing requires expertise in the

  8. A Color Topographic Map Based on the Dichromatic Reflectance Model

    Directory of Open Access Journals (Sweden)

    Bertrand Zavidovique

    2008-04-01

    Full Text Available Topographic maps are an interesting alternative to edge-based techniques common in computer vision applications. Indeed, unlike edges, level lines are closed and less sensitive to external parameters. They provide a compact geometrical representation of images and they are, to some extent, robust to contrast changes. The aim of this paper is to propose a novel and vectorial representation of color topographic maps. In contrast with existing color topographic maps, it does not require any color conversion. For this purpose, our technique refers to the dichromatic reflectance model, which explains the distribution of colors as the mixture of two reflectance components, related either to the body or to the specular reflection. Thus, instead of defining the topographic map along the sole luminance direction in the RGB space, we propose to design color lines along each dominant color vector, from the body reflection. Experimental results show that this approach provides a better tradeoff between the compactness and the quality of a topographic map.

  9. A Color Topographic Map Based on the Dichromatic Reflectance Model

    Directory of Open Access Journals (Sweden)

    Gouiffès Michèle

    2008-01-01

    Full Text Available Abstract Topographic maps are an interesting alternative to edge-based techniques common in computer vision applications. Indeed, unlike edges, level lines are closed and less sensitive to external parameters. They provide a compact geometrical representation of images and they are, to some extent, robust to contrast changes. The aim of this paper is to propose a novel and vectorial representation of color topographic maps. In contrast with existing color topographic maps, it does not require any color conversion. For this purpose, our technique refers to the dichromatic reflectance model, which explains the distribution of colors as the mixture of two reflectance components, related either to the body or to the specular reflection. Thus, instead of defining the topographic map along the sole luminance direction in the RGB space, we propose to design color lines along each dominant color vector, from the body reflection. Experimental results show that this approach provides a better tradeoff between the compactness and the quality of a topographic map.

  10. Low-energy microscopic models for iron-based superconductors: a review

    Science.gov (United States)

    Fernandes, Rafael M.; Chubukov, Andrey V.

    2017-01-01

    The development of sensible microscopic models is essential to elucidate the normal-state and superconducting properties of the iron-based superconductors. Because these materials are mostly metallic, a good starting point is an effective low-energy model that captures the electronic states near the Fermi level and their interactions. However, in contrast to cuprates, iron-based high-T c compounds are multi-orbital systems with Hubbard and Hund interactions, resulting in a rather involved 10-orbital lattice model. Here we review different minimal models that have been proposed to unveil the universal features of these systems. We first review minimal models defined solely in the orbital basis, which focus on a particular subspace of orbitals, or solely in the band basis, which rely only on the geometry of the Fermi surface. The former, while providing important qualitative insight into the role of the orbital degrees of freedom, do not distinguish between high-energy and low-energy sectors and, for this reason, generally do not go beyond mean-field. The latter allow one to go beyond mean-field and investigate the interplay between superconducting and magnetic orders as well as Ising-nematic order. However, they cannot capture orbital-dependent features like spontaneous orbital order. We then review recent proposals for a minimal model that operates in the band basis but fully incorporates the orbital composition and symmetries of the low-energy excitations. We discuss the results of the renormalization group study of such a model, particularly of the interplay between superconductivity, magnetism, and spontaneous orbital order, and compare theoretical predictions with experiments on iron pnictides and chalcogenides. We also discuss the impact of the glide-plane symmetry on the low-energy models, highlighting the key role played by the spin-orbit coupling.

  11. Electrical Compact Modeling of Graphene Base Transistors

    Directory of Open Access Journals (Sweden)

    Sébastien Frégonèse

    2015-11-01

    Full Text Available Following the recent development of the Graphene Base Transistor (GBT, a new electrical compact model for GBT devices is proposed. The transistor model includes the quantum capacitance model to obtain a self-consistent base potential. It also uses a versatile transfer current equation to be compatible with the different possible GBT configurations and it account for high injection conditions thanks to a transit time based charge model. Finally, the developed large signal model has been implemented in Verilog-A code and can be used for simulation in a standard circuit design environment such as Cadence or ADS. This model has been verified using advanced numerical simulation.

  12. Hierarchical Geometric Constraint Model for Parametric Feature Based Modeling

    Institute of Scientific and Technical Information of China (English)

    高曙明; 彭群生

    1997-01-01

    A new geometric constraint model is described,which is hierarchical and suitable for parametric feature based modeling.In this model,different levels of geometric information are repesented to support various stages of a design process.An efficient approach to parametric feature based modeling is also presented,adopting the high level geometric constraint model.The low level geometric model such as B-reps can be derived automatically from the hig level geometric constraint model,enabling designers to perform their task of detailed design.

  13. Continuous biogas production from fodder beet silage as sole substrate

    Energy Technology Data Exchange (ETDEWEB)

    Scherer, P.A.; Dobler, S.; Rohardt, S. [University of Applied Sciences, Hamburg (Germany). Research Centre of Environmental Bioengineering and Applied Biotechnology; Loock, R.; Buettner, B.; Noeldeke, P.; Brettschuh, A. [Loock Environmental Technologies, Hamburg (Germany)

    2003-07-01

    Since April 2000 a two-step anaerobic plant with two subsequent 500 m{sup 3} reactors has been producing biogas from fodder beet silage (pH 4.1) as the sole substrate. The plant is located at Kirchlengern near Bielefeld, Germany. Initially the reactors were inoculated with swine manure at 37{sup o}C. After a start-up phase the process was sustained at pH 7.5-8.0 by feeding with the silage as sole substrate twice a day. Parallel to the biogas plant at Kirchlengern four one-step laboratory reactors were continuously driven at temperatures of 37{sup o}C, 45{sup o}C, 60{sup o}C and 65{sup o}C. They were fed with the same silage, but only once per day (one impulse). The organic loading rate (OLR) was adjusted to 3.9 g volatile solids (VS)/(l*d) with a concomitant hydraulic retention time (HRT) of 27 d. There was no problem with starting the reactors, but after 86 days the volumetric gas production of the 65{sup o}C reactor ceased and a high amount of approximately 130 mM propionate could be determined. By decreasing the temperature down to 60{sup o}C a stable reactor performance was recovered for a period of at least 250 further days. During impulse feeding it was observed that the quickest recovery of gas production could be observed at 37{sup o}C or at 45{sup o}C. Recovery of 75% gas volume (related to the value before or after impulse feeding) was obtained after 5.5 and 7.5 h of feeding time point whereas the 60{sup o}C reactor needed 16 h. Slight significant differences were seen in the spectrum of volatile fatty acids (VFA) reaching at 37{sup o} or 45{sup o}C its maximum with 10-30 mM total VFA at 2-3 h after feeding. After this the VFA level declined to nearly zero (except for the 60{sup o}C reactor). Therefore the 37{sup o}C reactor was favoured. A double experiment with a second 37{sup o}C reactor was started by a somewhat different inoculation procedure from the remaining 3 reactors, but revealed similar results. By increasing the temperature no significantly

  14. The Culture Based Model: Constructing a Model of Culture

    Science.gov (United States)

    Young, Patricia A.

    2008-01-01

    Recent trends reveal that models of culture aid in mapping the design and analysis of information and communication technologies. Therefore, models of culture are powerful tools to guide the building of instructional products and services. This research examines the construction of the culture based model (CBM), a model of culture that evolved…

  15. Oil-in-oil emulsions stabilised solely by solid particles.

    Science.gov (United States)

    Binks, Bernard P; Tyowua, Andrew T

    2016-01-21

    A brief review of the stabilisation of emulsions of two immiscible oils is given. We then describe the use of fumed silica particles coated with either hydrocarbon or fluorocarbon groups in acting as sole stabilisers of emulsions of various vegetable oils with linear silicone oils (PDMS) of different viscosity. Transitional phase inversion of emulsions, containing equal volumes of the two oils, from silicone-in-vegetable (S/V) to vegetable-in-silicone (V/S) occurs upon increasing the hydrophobicity of the particles. Close to inversion, emulsions are stable to coalescence and gravity-induced separation for at least one year. Increasing the viscosity of the silicone oil enables stable S/V emulsions to be prepared even with relatively hydrophilic particles. Predictions of emulsion type from calculated contact angles of a silica particle at the oil-oil interface are in agreement with experiment provided a small polar contribution to the surface energy of the oils is included. We also show that stable multiple emulsions of V/S/V can be prepared in a two-step procedure using two particle types of different hydrophobicity. At fixed particle concentration, catastrophic phase inversion of emulsions from V/S to S/V can be effected by increasing the volume fraction of vegetable oil. Finally, in the case of sunflower oil + 20 cS PDMS, the study is extended to particles other than silica which differ in chemical type, particle size and particle shape. Consistent with the above findings, we find that only sufficiently hydrophobic particles (clay, zinc oxide, silicone, calcium carbonate) can act as efficient V/S emulsion stabilisers.

  16. Improving Agent Based Modeling of Critical Incidents

    Directory of Open Access Journals (Sweden)

    Robert Till

    2010-04-01

    Full Text Available Agent Based Modeling (ABM is a powerful method that has been used to simulate potential critical incidents in the infrastructure and built environments. This paper will discuss the modeling of some critical incidents currently simulated using ABM and how they may be expanded and improved by using better physiological modeling, psychological modeling, modeling the actions of interveners, introducing Geographic Information Systems (GIS and open source models.

  17. Testing Strategies for Model-Based Development

    Science.gov (United States)

    Heimdahl, Mats P. E.; Whalen, Mike; Rajan, Ajitha; Miller, Steven P.

    2006-01-01

    This report presents an approach for testing artifacts generated in a model-based development process. This approach divides the traditional testing process into two parts: requirements-based testing (validation testing) which determines whether the model implements the high-level requirements and model-based testing (conformance testing) which determines whether the code generated from a model is behaviorally equivalent to the model. The goals of the two processes differ significantly and this report explores suitable testing metrics and automation strategies for each. To support requirements-based testing, we define novel objective requirements coverage metrics similar to existing specification and code coverage metrics. For model-based testing, we briefly describe automation strategies and examine the fault-finding capability of different structural coverage metrics using tests automatically generated from the model.

  18. U1 and U2 small nuclear RNA genetic linkage: a novel molecular tool for identification of six sole species (Soleidae, Pleuronectiformes).

    Science.gov (United States)

    Manchado, Manuel; Rebordinos, Laureana; Infante, Carlos

    2006-05-31

    We evaluated the usefulness of a genetic linkage between the U1 and U2 small nuclear RNAs for species identification. Six soles belonging to the genera Solea, Dicologlossa, and Microchirus were studied. A simple methodology based on two single PCRs is described. Reproducible band profiles were generated for all samples. This rapid and discriminatory molecular method is highly promising for determining the authenticity of sole fillets in the food industry.

  19. Model-Based Enterprise Summit Report

    Science.gov (United States)

    2014-02-01

    Models Become Much More Efficient and Effective When Coupled With Knowledge Design Advisors CAD Fit Machine Motion KanBan Trigger Models Tolerance...Based Enterprise Geometry Kinematics Design Advisors Control Physics Planning System Models CAD Fit Machine Motion KanBan Trigger Models Tolerance

  20. Probabilistic Model-Based Safety Analysis

    CERN Document Server

    Güdemann, Matthias; 10.4204/EPTCS.28.8

    2010-01-01

    Model-based safety analysis approaches aim at finding critical failure combinations by analysis of models of the whole system (i.e. software, hardware, failure modes and environment). The advantage of these methods compared to traditional approaches is that the analysis of the whole system gives more precise results. Only few model-based approaches have been applied to answer quantitative questions in safety analysis, often limited to analysis of specific failure propagation models, limited types of failure modes or without system dynamics and behavior, as direct quantitative analysis is uses large amounts of computing resources. New achievements in the domain of (probabilistic) model-checking now allow for overcoming this problem. This paper shows how functional models based on synchronous parallel semantics, which can be used for system design, implementation and qualitative safety analysis, can be directly re-used for (model-based) quantitative safety analysis. Accurate modeling of different types of proba...

  1. Immunohistochemical diagnosis of tenacibaculosis in paraffin-embedded tissues of Senegalese sole Solea senegalensis Kaup, 1858.

    Science.gov (United States)

    Faílde, L D; Bermúdez, R; Losada, A P; Riaza, A; Santos, Y; Quiroga, M I

    2014-11-01

    A sensitive and specific immunohistochemical technique was developed to improve the diagnosis of tenacibaculosis and to better understand its pathogenesis. Senegalese sole Solea senegalensis Kaup, 1858 were inoculated subcutaneously with a bacterial suspension of Tenacibaculum maritimum, and samples were taken at different hours post-inoculation. Sections from different organs were used as positive controls. In addition, a total of 128 field samples from different organs collected from tenacibaculosis outbreaks were used. Tenacibaculum maritimum antigens were detected in several organs of experimentally infected Senegalese sole and in at least one of the tissues from fish suffering from natural tenacibaculosis previously confirmed by culture and PCR-based methods. In fish collected during outbreaks, a strong positive reaction was detected in ulcerative skin areas. Moreover, bacterial antigen was identified inside scale pockets and in sites of the skin with mild lesion. In kidney and spleen, evident immunostaining of bacterial antigen was detected in both naturally and experimentally infected fish. Besides, the presence of T. maritimum in the intestinal tract without associated histological changes suggests that this organ may act as a reservoir for T. maritimum. The results of this study confirm the usefulness of IHC for the diagnosis of tenacibaculosis in paraffin-embedded tissues. © 2013 John Wiley & Sons Ltd.

  2. Isolation and Characterization of Pathogenic Listonella anguillarum of Diseased Half-Smooth Tongue Sole (Cynoglossus semilaevis Günther)

    Institute of Scientific and Technical Information of China (English)

    TANG Xiaoqian; ZHOU Li; ZHAN Wenbin

    2008-01-01

    Studies were conducted to determine the cause of the acute mortality of half-smooth tongue sole Cynoglossus semilaevis Günther juveniles in a fish farm in Jimo, Shandong Province, China, in June 2006. Gross signs of the diseased tongue sole included several petechiae and ecchymoses on the body and fin necrosis and hemorrhagic lesion at the base of the fin. Bacteria were isolated from kidney, liver and hemorrhagic lesions of the diseased tongue sole. Among14 strains, SJ060621 was proved to be highly virulent to juvenile tongue sole with LD50 value of 1.0×105 colony forming units (CFU)mL-1, while the remaining 13 were avirulent. Among the 16 antibiotics tested, SJ060621 was sensitive to gentamicin and nitrofurantoin. It was identified as Listonella anguillarum with conventional plate and tube tests in combination with API 20E analysis. 16S rRNA gene and partial HSP60 gene sequenceing analysis revealed that the strain was highly homologous with L. anguillarum. Examination of the infected musculature by electron microscopy indicated numerous bacteria and lots of macrophages containing phagocytosed bacteria. Histopathological investigations revealed severe necrotic degenerative changes in the infected organs. Indirect immunofluorescence assay (IFA) was employed to detect the location of occurrence of bacteria, and bacteria were found in aggregations in the inflammatory areas in musculature.

  3. Dynamic modelling and analysis of biochemical networks: mechanism-based models and model-based experiments.

    Science.gov (United States)

    van Riel, Natal A W

    2006-12-01

    Systems biology applies quantitative, mechanistic modelling to study genetic networks, signal transduction pathways and metabolic networks. Mathematical models of biochemical networks can look very different. An important reason is that the purpose and application of a model are essential for the selection of the best mathematical framework. Fundamental aspects of selecting an appropriate modelling framework and a strategy for model building are discussed. Concepts and methods from system and control theory provide a sound basis for the further development of improved and dedicated computational tools for systems biology. Identification of the network components and rate constants that are most critical to the output behaviour of the system is one of the major problems raised in systems biology. Current approaches and methods of parameter sensitivity analysis and parameter estimation are reviewed. It is shown how these methods can be applied in the design of model-based experiments which iteratively yield models that are decreasingly wrong and increasingly gain predictive power.

  4. Firm Based Trade Models and Turkish Economy

    Directory of Open Access Journals (Sweden)

    Nilüfer ARGIN

    2015-12-01

    Full Text Available Among all international trade models, only The Firm Based Trade Models explains firm’s action and behavior in the world trade. The Firm Based Trade Models focuses on the trade behavior of individual firms that actually make intra industry trade. Firm Based Trade Models can explain globalization process truly. These approaches include multinational cooperation, supply chain and outsourcing also. Our paper aims to explain and analyze Turkish export with Firm Based Trade Models’ context. We use UNCTAD data on exports by SITC Rev 3 categorization to explain total export and 255 products and calculate intensive-extensive margins of Turkish firms.

  5. Traceability in Model-Based Testing

    Directory of Open Access Journals (Sweden)

    Mathew George

    2012-11-01

    Full Text Available The growing complexities of software and the demand for shorter time to market are two important challenges that face today’s IT industry. These challenges demand the increase of both productivity and quality of software. Model-based testing is a promising technique for meeting these challenges. Traceability modeling is a key issue and challenge in model-based testing. Relationships between the different models will help to navigate from one model to another, and trace back to the respective requirements and the design model when the test fails. In this paper, we present an approach for bridging the gaps between the different models in model-based testing. We propose relation definition markup language (RDML for defining the relationships between models.

  6. Lévy-based growth models

    DEFF Research Database (Denmark)

    Jónsdóttir, Kristjana Ýr; Schmiegel, Jürgen; Jensen, Eva Bjørn Vedel

    2008-01-01

    In the present paper, we give a condensed review, for the nonspecialist reader, of a new modelling framework for spatio-temporal processes, based on Lévy theory. We show the potential of the approach in stochastic geometry and spatial statistics by studying Lévy-based growth modelling of planar...... objects. The growth models considered are spatio-temporal stochastic processes on the circle. As a by product, flexible new models for space–time covariance functions on the circle are provided. An application of the Lévy-based growth models to tumour growth is discussed....

  7. Base Flow Model Validation Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The innovation is the systematic "building-block" validation of CFD/turbulence models employing a GUI driven CFD code (RPFM) and existing as well as new data sets to...

  8. Distributed Prognostics Based on Structural Model Decomposition

    Data.gov (United States)

    National Aeronautics and Space Administration — Within systems health management, prognostics focuses on predicting the remaining useful life of a system. In the model-based prognostics paradigm, physics-based...

  9. Dissolution-precipitation processes governing the carbonation and silicification of the serpentinite sole of the New Caledonia ophiolite

    Science.gov (United States)

    Ulrich, M.; Munoz, M.; Guillot, S.; Cathelineau, M.; Picard, C.; Quesnel, B.; Boulvais, P.; Couteau, C.

    2014-12-01

    The weathering of mantle peridotite tectonically exposed to the atmosphere leads commonly to natural carbonation processes. Extensive cryptocrystalline magnesite veins and stock-work are widespread in the serpentinite sole of the New Caledonia ophiolite. Silica is systematically associated with magnesite. It is commonly admitted that Mg and Si are released during the laterization of overlying peridotites. Thus, the occurrence of these veins is generally attributed to a per descensum mechanism that involves the infiltration of meteoric waters enriched in dissolved atmospheric CO2. In this study, we investigate serpentinite carbonation processes, and related silicification, based on a detailed petrographic and crystal chemical study of serpentinites. The relationships between serpentine and alteration products are described using an original method for the analysis of micro-X-ray fluorescence images performed at the centimeter scale. Our investigations highlight a carbonation mechanism, together with precipitation of amorphous silica and sepiolite, based on a dissolution-precipitation process. In contrast with the per descensum Mg/Si-enrichment model that is mainly concentrated in rock fractures, dissolution-precipitation process is much more pervasive. Thus, although the texture of rocks remains relatively preserved, this process extends more widely into the rock and may represent a major part of total carbonation of the ophiolite.

  10. Numerical Modeling of Microbial Fuel Cell Based on Redox Electron Mediator

    Institute of Scientific and Technical Information of China (English)

    Nanqi Ren

    2015-01-01

    To investigate the behavior of redox electron mediator and its impact to power generation of microbial fuel cell ( MFC ) , this study carries out the numerical modeling of a typical two⁃chamber MFC based on assumption of interfacial electron transfer via redox electron mediator and acetate as sole electron donor. The model simulates the development of cell voltage, current, substrate concentration, redox electron mediator concentration, polarization and power density output under defined conditions. The results demonstrate that the developed models can fit the experimental results well on a qualitative basis, and concentration of electron reduced mediator plays a dominant role in electron transfer process, and the mass transfer may constitute the limiting step when its concentration is at a relatively low level. This study not only provides a better understanding of electron redox mediator behavior during power generation, but also suggests a strategy to improve electron transfer in the anode of MFC.

  11. Adversarial intent modeling using embedded simulation and temporal Bayesian knowledge bases

    Science.gov (United States)

    Pioch, Nicholas J.; Melhuish, James; Seidel, Andy; Santos, Eugene, Jr.; Li, Deqing; Gorniak, Mark

    2009-05-01

    To foster shared battlespace awareness among air strategy planners, BAE Systems has developed Commander's Model Integration and Simulation Toolkit (CMIST), an Integrated Development Environment for authoring, integration, validation, and debugging of models relating multiple domains, including political, military, social, economic and information. CMIST provides a unified graphical user interface for such systems of systems modeling, spanning several disparate modeling paradigms. Here, we briefly review the CMIST architecture and then compare modeling results using two approaches to intent modeling. The first uses reactive agents with simplified behavior models that apply rule-based triggers to initiate actions based solely on observations of the external world at the current time in the simulation. The second method models proactive agents running an embedded CMIST simulation representing their projection of how events may unfold in the future in order to take early preventative action. Finally, we discuss a recent extension to CMIST that incorporates Temporal Bayesian Knowledge Bases for more sophisticated models of adversarial intent that are capable of inferring goals and future actions given evidence of current actions at particular times.

  12. Distributed hydrological models: comparison between TOPKAPI, a physically based model and TETIS, a conceptually based model

    Science.gov (United States)

    Ortiz, E.; Guna, V.

    2009-04-01

    The present work aims to carry out a comparison between two distributed hydrological models, the TOPKAPI (Ciarapica and Todini, 1998; Todini and Ciarapica, 2001) and TETIS (Vélez, J. J.; Vélez J. I. and Francés, F, 2002) models, obtaining the hydrological solution computed on the basis of the same storm events. The first model is physically based and the second one is conceptually based. The analysis was performed on the 21,4 km2 Goodwin Creek watershed, located in Panola County, Mississippi. This watershed extensively monitored by the Agricultural Research Service (ARS) National Sediment Laboratory (NSL) has been chosen because it offers a complete database compiling precipitation (16 rain gauges), runoff (6 discharge stations) and GIS data. Three storm events were chosen to evaluate the performance of the two models: the first one was chosen to calibrate the models, and the other two to validate them. Both models performed a satisfactory hydrological response both in calibration and validation events. While for the TOPKAPI model it wasn't a real calibration, due to its really good performance with parameters modal values derived of watershed characteristics, for the TETIS model it has been necessary to perform a previous automatic calibration. This calibration was carried out using the data provided by the observed hydrograph, in order to adjust the modeĺs 9 correction factors. Keywords: TETIS, TOPKAPI, distributed models, hydrological response, ungauged basins.

  13. PCA-based lung motion model

    CERN Document Server

    Li, Ruijiang; Jia, Xun; Zhao, Tianyu; Lamb, James; Yang, Deshan; Low, Daniel A; Jiang, Steve B

    2010-01-01

    Organ motion induced by respiration may cause clinically significant targeting errors and greatly degrade the effectiveness of conformal radiotherapy. It is therefore crucial to be able to model respiratory motion accurately. A recently proposed lung motion model based on principal component analysis (PCA) has been shown to be promising on a few patients. However, there is still a need to understand the underlying reason why it works. In this paper, we present a much deeper and detailed analysis of the PCA-based lung motion model. We provide the theoretical justification of the effectiveness of PCA in modeling lung motion. We also prove that under certain conditions, the PCA motion model is equivalent to 5D motion model, which is based on physiology and anatomy of the lung. The modeling power of PCA model was tested on clinical data and the average 3D error was found to be below 1 mm.

  14. Integration of Simulink Models with Component-based Software Models

    DEFF Research Database (Denmark)

    Marian, Nicolae

    2008-01-01

    constructs and process flow, then software code is generated. A Simulink model is a representation of the design or implementation of a physical system that satisfies a set of requirements. A software component-based system aims to organize system architecture and behaviour as a means of computation...... constraints. COMDES (Component-based Design of Software for Distributed Embedded Systems) is such a component-based system framework developed by the software engineering group of Mads Clausen Institute for Product Innovation (MCI), University of Southern Denmark. Once specified, the software model has......Model based development aims to facilitate the development of embedded control systems by emphasizing the separation of the design level from the implementation level. Model based design involves the use of multiple models that represent different views of a system, having different semantics...

  15. A Multiple Model Approach to Modeling Based on LPF Algorithm

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Input-output data fitting methods are often used for unknown-structure nonlinear system modeling. Based on model-on-demand tactics, a multiple model approach to modeling for nonlinear systems is presented. The basic idea is to find out, from vast historical system input-output data sets, some data sets matching with the current working point, then to develop a local model using Local Polynomial Fitting (LPF) algorithm. With the change of working points, multiple local models are built, which realize the exact modeling for the global system. By comparing to other methods, the simulation results show good performance for its simple, effective and reliable estimation.``

  16. Behavior and Design Intent Based Product Modeling

    Directory of Open Access Journals (Sweden)

    László Horváth

    2004-11-01

    Full Text Available A knowledge based modeling of mechanical products is presented for industrial CAD/CAM systems. An active model is proposed that comprise knowledge from modeling procedures, generic part models and engineers. Present day models of mechanical systems do not contain data about the background of human decisions. This situation motivated the authors at their investigations on exchange design intent information between engineers. Their concept was extending of product models to be capable of description of design intent information. Several human-computer and human-human communication issues were considered. The complex communication problem has been divided into four sub-problems, namely communication of human intent source with the computer system, representation of human intent, exchange of intent data between modeling procedures and communication of the represented intent with humans. Paper discusses the scenario of intelligent modeling based engineering. Then key concepts for the application of computational intelligence in computer model based engineering systems are detailed including knowledge driven models as well as areas of their application. Next, behavior based models with intelligent content involving specifications and knowledge for the design processes are emphasized and an active part modeling is proposed and possibilities for its application are outlined. Finally, design intent supported intelligent modeling is discussed.

  17. Arc/Forearc Lengthening at Plate Triple Junctions and the Formation of Ophiolitic Soles

    Science.gov (United States)

    Casey, John; Dewey, John

    2013-04-01

    The principal enigma of large obducted ophiolite slabs is that they clearly must have been generated by some form of organized sea-floor spreading/plate-accretion, such as may be envisioned for the oceanic ridges, yet the volcanics commonly have arc affinity (Miyashiro) with boninites (high-temperature/low-pressure, high Mg and Si andesites), which are suggestive of a forearc origin. PT conditions under which boninites and metamorphic soles form and observations of modern forearc systems lead us to the conclusion that ophiolite formation is associated with overidding plate spreading centers that intersect the trench to form ridge-trench-trench of ridge-trench-tranform triple junctions. The spreading centers extend and lengthen the forearc parallel to the trench and by definition are in supra-subduction zone (SSZ) settings. Many ophiolites likewise have complexly-deformed associated mafic-ultramafic assemblages that suggest fracture zone/transform t along their frontal edges, which in turn has led to models involving the nucleation of subduction zones on fracture zones or transpressional transforms. Hitherto, arc-related sea-floor-spreading has been considered to be either pre-arc (fore-arc boninites) or post-arc (classic Karig-style back arc basins that trench-parallell split arcs). Syn-arc boninites and forearc oceanic spreading centers that involve a stable ridge/trench/trench triple or a ridge-trench-transform triple junction, the ridge being between the two upper plates, are consistent with large slab ophiolite formation in a readied obduction settting. The direction of subduction must be oblique with a different sense in the two subduction zones and the oblique subduction cannot be partitioned into trench orthogonal and parallel strike-slip components. As the ridge spreads, new oceanic lithosphere is created within the forearc, the arc and fore-arc lengthen significantly, and a syn-arc ophiolite forearc complex is generated by this mechanism. The ophiolite

  18. Model Validation in Ontology Based Transformations

    Directory of Open Access Journals (Sweden)

    Jesús M. Almendros-Jiménez

    2012-10-01

    Full Text Available Model Driven Engineering (MDE is an emerging approach of software engineering. MDE emphasizes the construction of models from which the implementation should be derived by applying model transformations. The Ontology Definition Meta-model (ODM has been proposed as a profile for UML models of the Web Ontology Language (OWL. In this context, transformations of UML models can be mapped into ODM/OWL transformations. On the other hand, model validation is a crucial task in model transformation. Meta-modeling permits to give a syntactic structure to source and target models. However, semantic requirements have to be imposed on source and target models. A given transformation will be sound when source and target models fulfill the syntactic and semantic requirements. In this paper, we present an approach for model validation in ODM based transformations. Adopting a logic programming based transformational approach we will show how it is possible to transform and validate models. Properties to be validated range from structural and semantic requirements of models (pre and post conditions to properties of the transformation (invariants. The approach has been applied to a well-known example of model transformation: the Entity-Relationship (ER to Relational Model (RM transformation.

  19. Comparing repetition-based melody segmentation models

    NARCIS (Netherlands)

    Rodríguez López, M.E.; de Haas, Bas; Volk, Anja

    2014-01-01

    This paper reports on a comparative study of computational melody segmentation models based on repetition detection. For the comparison we implemented five repetition-based segmentation models, and subsequently evaluated their capacity to automatically find melodic phrase boundaries in a corpus of 2

  20. A Role-Based Fuzzy Assignment Model

    Institute of Scientific and Technical Information of China (English)

    ZUO Bao-he; FENG Shan

    2002-01-01

    It's very important to dynamically assign the tasks to corresponding actors in workflow management system, especially in complex applications. This improves the flexibility of workflow systems.In this paper, a role-based workflow model with fuzzy optimized intelligent assignment is proposed and applied in the investment management system. A groupware-based software model is also proposed.

  1. Key-Based Data Model

    Science.gov (United States)

    1994-05-16

    prgresive repetition. It is used, principally , to train small units to pefom tasks requiring a high degree of teamwork, such as fire and maneuver actions in...an adminitative structure that has a mission. An established need based on a valid deficiency in an administrative structure with a mission. Person A

  2. Background based Gaussian mixture model lesion segmentation in PET

    Energy Technology Data Exchange (ETDEWEB)

    Soffientini, Chiara Dolores, E-mail: chiaradolores.soffientini@polimi.it; Baselli, Giuseppe [DEIB, Department of Electronics, Information, and Bioengineering, Politecnico di Milano, Piazza Leonardo da Vinci 32, Milan 20133 (Italy); De Bernardi, Elisabetta [Department of Medicine and Surgery, Tecnomed Foundation, University of Milano—Bicocca, Monza 20900 (Italy); Zito, Felicia; Castellani, Massimo [Nuclear Medicine Department, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, via Francesco Sforza 35, Milan 20122 (Italy)

    2016-05-15

    demonstrated. The inclusion of the spatial prior improved segmentation accuracy only for lesions surrounded by heterogeneous background: in the relevant simulation subset, the median VE significantly decreased from 13% to 7%. Results on clinical data were found in accordance with simulations, with absolute VE <7%, Dice >0.85, CE <0.30, and HD <0.81. Conclusions: The sole introduction of constraints based on background modeling outperformed standard GMM and the other tested algorithms. Insertion of a spatial prior improved the accuracy for realistic cases of objects in heterogeneous backgrounds. Moreover, robustness against initialization supports the applicability in a clinical setting. In conclusion, application-driven constraints can generally improve the capabilities of GMM and statistical clustering algorithms.

  3. Phylogenetic invariants for group-based models

    CERN Document Server

    Donten-Bury, Maria

    2010-01-01

    In this paper we investigate properties of algebraic varieties representing group-based phylogenetic models. We give the (first) example of a nonnormal general group-based model for an abelian group. Following Kaie Kubjas we also determine some invariants of group-based models showing that the associated varieties do not have to be deformation equivalent. We propose a method of generating many phylogenetic invariants and in particular we show that our approach gives the whole ideal of the claw tree for 3-Kimura model under the assumption of the conjecture of Sturmfels and Sullivant. This, combined with the results of Sturmfels and Sullivant, would enable to determine all phylogenetic invariants for any tree for 3-Kimura model and possibly for other group-based models.

  4. Model-based internal wave processing

    Energy Technology Data Exchange (ETDEWEB)

    Candy, J.V.; Chambers, D.H.

    1995-06-09

    A model-based approach is proposed to solve the oceanic internal wave signal processing problem that is based on state-space representations of the normal-mode vertical velocity and plane wave horizontal velocity propagation models. It is shown that these representations can be utilized to spatially propagate the modal (dept) vertical velocity functions given the basic parameters (wave numbers, Brunt-Vaisala frequency profile etc.) developed from the solution of the associated boundary value problem as well as the horizontal velocity components. Based on this framework, investigations are made of model-based solutions to the signal enhancement problem for internal waves.

  5. Agent-based modeling of sustainable behaviors

    CERN Document Server

    Sánchez-Maroño, Noelia; Fontenla-Romero, Oscar; Polhill, J; Craig, Tony; Bajo, Javier; Corchado, Juan

    2017-01-01

    Using the O.D.D. (Overview, Design concepts, Detail) protocol, this title explores the role of agent-based modeling in predicting the feasibility of various approaches to sustainability. The chapters incorporated in this volume consist of real case studies to illustrate the utility of agent-based modeling and complexity theory in discovering a path to more efficient and sustainable lifestyles. The topics covered within include: households' attitudes toward recycling, designing decision trees for representing sustainable behaviors, negotiation-based parking allocation, auction-based traffic signal control, and others. This selection of papers will be of interest to social scientists who wish to learn more about agent-based modeling as well as experts in the field of agent-based modeling.

  6. IP Network Management Model Based on NGOSS

    Institute of Scientific and Technical Information of China (English)

    ZHANG Jin-yu; LI Hong-hui; LIU Feng

    2004-01-01

    This paper addresses a management model for IP network based on Next Generation Operation Support System (NGOSS). It makes the network management on the base of all the operation actions of ISP, It provides QoS to user service through the whole path by providing end-to-end Service Level Agreements (SLA) management through whole path. Based on web and coordination technology, this paper gives an implement architecture of this model.

  7. Ultrasound-guided greater auricular nerve block as sole anesthetic for ear surgery

    Directory of Open Access Journals (Sweden)

    Michael K. Ritchie

    2016-05-01

    Full Text Available A greater auricular nerve (GAN block was used as the sole anesthetic for facial surgery in an 80-year-old male patient with multiple comorbidities which would have made general anesthesia challenging. The GAN provides sensation to the ear, mastoid process, parotid gland, and angle of the mandible. In addition to anesthesia for operating room surgery, the GAN block can be used for outpatient or emergency department procedures without the need for a separate anesthesia team. Although this nerve block has been performed using landmark-based techniques, the ultrasoundguided version offers several potential advantages. These advantages include increased reliability of the nerve block, as well as prevention of inadvertent vascular puncture or blockade of the phrenic nerve, brachial plexus, or deep cervical plexus. The increasing access to ultrasound technology for medical care providers outside the operating room makes this ultrasound guided block an increasingly viable alternative.

  8. CEAI: CCM based Email Authorship Identification Model

    DEFF Research Database (Denmark)

    Nizamani, Sarwat; Memon, Nasrullah

    2013-01-01

    In this paper we present a model for email authorship identification (EAI) by employing a Cluster-based Classification (CCM) technique. Traditionally, stylometric features have been successfully employed in various authorship analysis tasks; we extend the traditional feature-set to include some...... more interesting and effective features for email authorship identification (e.g. the last punctuation mark used in an email, the tendency of an author to use capitalization at the start of an email, or the punctuation after a greeting or farewell). We also included Info Gain feature selection based...... reveal that the proposed CCM-based email authorship identification model, along with the proposed feature set, outperforms the state-of-the-art support vector machine (SVM)-based models, as well as the models proposed by Iqbal et al. [1, 2]. The proposed model attains an accuracy rate of 94% for 10...

  9. Agent-based modeling and network dynamics

    CERN Document Server

    Namatame, Akira

    2016-01-01

    The book integrates agent-based modeling and network science. It is divided into three parts, namely, foundations, primary dynamics on and of social networks, and applications. The book begins with the network origin of agent-based models, known as cellular automata, and introduce a number of classic models, such as Schelling’s segregation model and Axelrod’s spatial game. The essence of the foundation part is the network-based agent-based models in which agents follow network-based decision rules. Under the influence of the substantial progress in network science in late 1990s, these models have been extended from using lattices into using small-world networks, scale-free networks, etc. The book also shows that the modern network science mainly driven by game-theorists and sociophysicists has inspired agent-based social scientists to develop alternative formation algorithms, known as agent-based social networks. The book reviews a number of pioneering and representative models in this family. Upon the gi...

  10. Simulation-based Manufacturing System Modeling

    Institute of Scientific and Technical Information of China (English)

    卫东; 金烨; 范秀敏; 严隽琪

    2003-01-01

    In recent years, computer simulation appears to be very advantageous technique for researching the resource-constrained manufacturing system. This paper presents an object-oriented simulation modeling method, which combines the merits of traditional methods such as IDEF0 and Petri Net. In this paper, a four-layer-one-angel hierarchical modeling framework based on OOP is defined. And the modeling description of these layers is expounded, such as: hybrid production control modeling and human resource dispatch modeling. To validate the modeling method, a case study of an auto-product line in a motor manufacturing company has been carried out.

  11. Model-Based Motion Tracking of Infants

    DEFF Research Database (Denmark)

    Olsen, Mikkel Damgaard; Herskind, Anna; Nielsen, Jens Bo;

    2014-01-01

    Even though motion tracking is a widely used technique to analyze and measure human movements, only a few studies focus on motion tracking of infants. In recent years, a number of studies have emerged focusing on analyzing the motion pattern of infants, using computer vision. Most of these studies...... are based on 2D images, but few are based on 3D information. In this paper, we present a model-based approach for tracking infants in 3D. The study extends a novel study on graph-based motion tracking of infants and we show that the extension improves the tracking results. A 3D model is constructed...... that resembles the body surface of an infant, where the model is based on simple geometric shapes and a hierarchical skeleton model....

  12. Energy based prediction models for building acoustics

    DEFF Research Database (Denmark)

    Brunskog, Jonas

    2012-01-01

    In order to reach robust and simplified yet accurate prediction models, energy based principle are commonly used in many fields of acoustics, especially in building acoustics. This includes simple energy flow models, the framework of statistical energy analysis (SEA) as well as more elaborated...... principles as, e.g., wave intensity analysis (WIA). The European standards for building acoustic predictions, the EN 12354 series, are based on energy flow and SEA principles. In the present paper, different energy based prediction models are discussed and critically reviewed. Special attention is placed...

  13. Probabilistic Model-Based Background Subtraction

    DEFF Research Database (Denmark)

    Krüger, Volker; Andersen, Jakob; Prehn, Thomas

    2005-01-01

    manner. Bayesian propagation over time is used for proper model selection and tracking during model-based background subtraction. Bayes propagation is attractive in our application as it allows to deal with uncertainties during tracking. We have tested our approach on suitable outdoor video data....... is the correlation between pixels. In this paper we introduce a model-based background subtraction approach which facilitates prior knowledge of pixel correlations for clearer and better results. Model knowledge is being learned from good training video data, the data is stored for fast access in a hierarchical...

  14. Software Testing Method Based on Model Comparison

    Institute of Scientific and Technical Information of China (English)

    XIE Xiao-dong; LU Yan-sheng; MAO Cheng-yin

    2008-01-01

    A model comparison based software testing method (MCST) is proposed. In this method, the requirements and programs of software under test are transformed into the ones in the same form, and described by the same model describe language (MDL).Then, the requirements are transformed into a specification model and the programs into an implementation model. Thus, the elements and structures of the two models are compared, and the differences between them are obtained. Based on the diffrences, a test suite is generated. Different MDLs can be chosen for the software under test. The usages of two classical MDLs in MCST, the equivalence classes model and the extended finite state machine (EFSM) model, are described with example applications. The results show that the test suites generated by MCST are more efficient and smaller than some other testing methods, such as the path-coverage testing method, the object state diagram testing method, etc.

  15. Instance-Based Generative Biological Shape Modeling.

    Science.gov (United States)

    Peng, Tao; Wang, Wei; Rohde, Gustavo K; Murphy, Robert F

    2009-01-01

    Biological shape modeling is an essential task that is required for systems biology efforts to simulate complex cell behaviors. Statistical learning methods have been used to build generative shape models based on reconstructive shape parameters extracted from microscope image collections. However, such parametric modeling approaches are usually limited to simple shapes and easily-modeled parameter distributions. Moreover, to maximize the reconstruction accuracy, significant effort is required to design models for specific datasets or patterns. We have therefore developed an instance-based approach to model biological shapes within a shape space built upon diffeomorphic measurement. We also designed a recursive interpolation algorithm to probabilistically synthesize new shape instances using the shape space model and the original instances. The method is quite generalizable and therefore can be applied to most nuclear, cell and protein object shapes, in both 2D and 3D.

  16. Joint kinematic calculation based on clinical direct kinematic versus inverse kinematic gait models.

    Science.gov (United States)

    Kainz, H; Modenese, L; Lloyd, D G; Maine, S; Walsh, H P J; Carty, C P

    2016-06-14

    Most clinical gait laboratories use the conventional gait analysis model. This model uses a computational method called Direct Kinematics (DK) to calculate joint kinematics. In contrast, musculoskeletal modelling approaches use Inverse Kinematics (IK) to obtain joint angles. IK allows additional analysis (e.g. muscle-tendon length estimates), which may provide valuable information for clinical decision-making in people with movement disorders. The twofold aims of the current study were: (1) to compare joint kinematics obtained by a clinical DK model (Vicon Plug-in-Gait) with those produced by a widely used IK model (available with the OpenSim distribution), and (2) to evaluate the difference in joint kinematics that can be solely attributed to the different computational methods (DK versus IK), anatomical models and marker sets by using MRI based models. Eight children with cerebral palsy were recruited and presented for gait and MRI data collection sessions. Differences in joint kinematics up to 13° were found between the Plug-in-Gait and the gait 2392 OpenSim model. The majority of these differences (94.4%) were attributed to differences in the anatomical models, which included different anatomical segment frames and joint constraints. Different computational methods (DK versus IK) were responsible for only 2.7% of the differences. We recommend using the same anatomical model for kinematic and musculoskeletal analysis to ensure consistency between the obtained joint angles and musculoskeletal estimates.

  17. 78 FR 19261 - Safe Drinking Water Act Sole Source Aquifer Program; Designation of Bainbridge Island, Washington...

    Science.gov (United States)

    2013-03-29

    ... AGENCY Safe Drinking Water Act Sole Source Aquifer Program; Designation of Bainbridge Island, Washington.... SUMMARY: Notice is hereby given that pursuant to Section 1424(e) of the Safe Drinking Water Act, the... Aquifer System located in Kitsap County, Washington is the sole or principle source of drinking water...

  18. 26 CFR 1.1081-3 - Exchanges of stock or securities solely for stock or securities.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 11 2010-04-01 2010-04-01 true Exchanges of stock or securities solely for stock or securities. 1.1081-3 Section 1.1081-3 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF... § 1.1081-3 Exchanges of stock or securities solely for stock or securities. The exchange, without...

  19. Distributed Prognostics based on Structural Model Decomposition

    Science.gov (United States)

    Daigle, Matthew J.; Bregon, Anibal; Roychoudhury, I.

    2014-01-01

    Within systems health management, prognostics focuses on predicting the remaining useful life of a system. In the model-based prognostics paradigm, physics-based models are constructed that describe the operation of a system and how it fails. Such approaches consist of an estimation phase, in which the health state of the system is first identified, and a prediction phase, in which the health state is projected forward in time to determine the end of life. Centralized solutions to these problems are often computationally expensive, do not scale well as the size of the system grows, and introduce a single point of failure. In this paper, we propose a novel distributed model-based prognostics scheme that formally describes how to decompose both the estimation and prediction problems into independent local subproblems whose solutions may be easily composed into a global solution. The decomposition of the prognostics problem is achieved through structural decomposition of the underlying models. The decomposition algorithm creates from the global system model a set of local submodels suitable for prognostics. Independent local estimation and prediction problems are formed based on these local submodels, resulting in a scalable distributed prognostics approach that allows the local subproblems to be solved in parallel, thus offering increases in computational efficiency. Using a centrifugal pump as a case study, we perform a number of simulation-based experiments to demonstrate the distributed approach, compare the performance with a centralized approach, and establish its scalability. Index Terms-model-based prognostics, distributed prognostics, structural model decomposition ABBREVIATIONS

  20. Sketch-based Interfaces and Modeling

    CERN Document Server

    Jorge, Joaquim

    2011-01-01

    The field of sketch-based interfaces and modeling (SBIM) is concerned with developing methods and techniques to enable users to interact with a computer through sketching - a simple, yet highly expressive medium. SBIM blends concepts from computer graphics, human-computer interaction, artificial intelligence, and machine learning. Recent improvements in hardware, coupled with new machine learning techniques for more accurate recognition, and more robust depth inferencing techniques for sketch-based modeling, have resulted in an explosion of both sketch-based interfaces and pen-based computing

  1. The comparison of nitrogen use and leaching in sole cropped versus intercropped pea and barley

    DEFF Research Database (Denmark)

    Hauggaard-Nielsen, H.; Ambus, P.; Jensen, E.S.

    2003-01-01

    The effect of sole and intercropping of field pea (Pisum sativum L.) and spring barley (Hordeum vulgare L.) and of crop residue management on crop yield, NO3- leaching and N balance in the cropping system was tested in a 2-year lysimeter experiment on a temperate sandy loam soil. The crop rotation...... was pea and barley sole and intercrops followed by winter-rye and a fallow period. The Land Equivalent Ratio (LER), which is defined as the relative land area under sole crops that is required to produce the yields achieved in intercropping, was used to compare intercropping performance relative to sole...... from the sole cropped pea and barley lysimeters. Soil N balances indicated depletion of N in the soil-plant system during the experimental period, independent of cropping system and residue management. N complementarity in the cropping system and the synchrony between residual N availability and crop N...

  2. The great melting pot. Common sole population connectivity assessed by otolith and water fingerprints.

    Science.gov (United States)

    Morat, Fabien; Letourneur, Yves; Dierking, Jan; Pécheyran, Christophe; Bareille, Gilles; Blamart, Dominique; Harmelin-Vivien, Mireille

    2014-01-01

    Quantifying the scale and importance of individual dispersion between populations and life stages is a key challenge in marine ecology. The common sole (Solea solea), an important commercial flatfish in the North Sea, Atlantic Ocean and the Mediterranean Sea, has a marine pelagic larval stage, a benthic juvenile stage in coastal nurseries (lagoons, estuaries or shallow marine areas) and a benthic adult stage in deeper marine waters on the continental shelf. To date, the ecological connectivity among these life stages has been little assessed in the Mediterranean. Here, such an assessment is provided for the first time for the Gulf of Lions, NW Mediterranean, based on a dataset on otolith microchemistry and stable isotopic composition as indicators of the water masses inhabited by individual fish. Specifically, otolith Ba/Ca and Sr/Ca profiles, and δ(13)C and δ(18)O values of adults collected in four areas of the Gulf of Lions were compared with those of young-of-the-year collected in different coastal nurseries. Results showed that a high proportion of adults (>46%) were influenced by river inputs during their larval stage. Furthermore Sr/Ca ratios and the otolith length at one year of age revealed that most adults (∼70%) spent their juvenile stage in nurseries with high salinity, whereas the remainder used brackish environments. In total, data were consistent with the use of six nursery types, three with high salinity (marine areas and two types of highly saline lagoons) and three brackish (coastal areas near river mouths, and two types of brackish environments), all of which contributed to the replenishment of adult populations. These finding implicated panmixia in sole population in the Gulf of Lions and claimed for a habitat integrated management of fisheries.

  3. Spatial and ontogenetic variability in the chemical composition of juvenile common sole ( Solea solea) otoliths

    Science.gov (United States)

    Tanner, S. E.; Vasconcelos, R. P.; Reis-Santos, P.; Cabral, H. N.; Thorrold, S. R.

    2011-01-01

    A description of variations in the chemical composition of fish otoliths at different spatial scales and life history stages is a prerequisite for their use as natural tags in fish population connectivity and migration studies. Otolith geochemistry of juvenile common sole ( Solea solea), a marine migrant species collected in six Portuguese estuaries was examined. Elemental ratios (Mg:Ca, Mn:Ca, Cu:Ca, Sr:Ca, Ba:Ca, Pb:Ca) were analysed in two zones of the right otolith (corresponding to late larval and juvenile stages) using laser ablation inductively coupled plasma mass spectrometry (ICP-MS). Stable carbon and oxygen isotopes (δ 13C and δ 18O) were determined in left otoliths using isotopic ratio monitoring mass spectrometry (irm-MS). Significant differences in otolith geochemical signatures were found among estuaries, among sites within estuaries and between otolith zones. Several elemental ratios (Mg:Ca, Mn:Ca, Cu:Ca and Sr:Ca) showed consistent patterns between otolith zones and were likely influenced by environmental factors and ontogenetic effects associated with physiological changes during metamorphosis. Assignment of individuals to their collection estuary based on the otolith geochemical signatures was more accurate at the site level (81%) than among estuaries (69%). Site temperature was not correlated with any of the elemental or isotope ratios, but salinity was significantly correlated with Ba:Ca, δ 13C and δ 18O. Observed spatial variations among estuaries and sites within estuaries indicate that geochemical signatures in otoliths are accurate natural tags of estuarine habitat in common sole. Nevertheless, the significant variations observed between otolith zones should be taken into account in the design of population connectivity studies.

  4. Multiscale agent-based consumer market modeling.

    Energy Technology Data Exchange (ETDEWEB)

    North, M. J.; Macal, C. M.; St. Aubin, J.; Thimmapuram, P.; Bragen, M.; Hahn, J.; Karr, J.; Brigham, N.; Lacy, M. E.; Hampton, D.; Decision and Information Sciences; Procter & Gamble Co.

    2010-05-01

    Consumer markets have been studied in great depth, and many techniques have been used to represent them. These have included regression-based models, logit models, and theoretical market-level models, such as the NBD-Dirichlet approach. Although many important contributions and insights have resulted from studies that relied on these models, there is still a need for a model that could more holistically represent the interdependencies of the decisions made by consumers, retailers, and manufacturers. When the need is for a model that could be used repeatedly over time to support decisions in an industrial setting, it is particularly critical. Although some existing methods can, in principle, represent such complex interdependencies, their capabilities might be outstripped if they had to be used for industrial applications, because of the details this type of modeling requires. However, a complementary method - agent-based modeling - shows promise for addressing these issues. Agent-based models use business-driven rules for individuals (e.g., individual consumer rules for buying items, individual retailer rules for stocking items, or individual firm rules for advertizing items) to determine holistic, system-level outcomes (e.g., to determine if brand X's market share is increasing). We applied agent-based modeling to develop a multi-scale consumer market model. We then conducted calibration, verification, and validation tests of this model. The model was successfully applied by Procter & Gamble to several challenging business problems. In these situations, it directly influenced managerial decision making and produced substantial cost savings.

  5. PDF-based heterogeneous multiscale filtration model.

    Science.gov (United States)

    Gong, Jian; Rutland, Christopher J

    2015-04-21

    Motivated by modeling of gasoline particulate filters (GPFs), a probability density function (PDF) based heterogeneous multiscale filtration (HMF) model is developed to calculate filtration efficiency of clean particulate filters. A new methodology based on statistical theory and classic filtration theory is developed in the HMF model. Based on the analysis of experimental porosimetry data, a pore size probability density function is introduced to represent heterogeneity and multiscale characteristics of the porous wall. The filtration efficiency of a filter can be calculated as the sum of the contributions of individual collectors. The resulting HMF model overcomes the limitations of classic mean filtration models which rely on tuning of the mean collector size. Sensitivity analysis shows that the HMF model recovers the classical mean model when the pore size variance is very small. The HMF model is validated by fundamental filtration experimental data from different scales of filter samples. The model shows a good agreement with experimental data at various operating conditions. The effects of the microstructure of filters on filtration efficiency as well as the most penetrating particle size are correctly predicted by the model.

  6. Workflow-Based Dynamic Enterprise Modeling

    Institute of Scientific and Technical Information of China (English)

    黄双喜; 范玉顺; 罗海滨; 林慧萍

    2002-01-01

    Traditional systems for enterprise modeling and business process control are often static and cannot adapt to the changing environment. This paper presents a workflow-based method to dynamically execute the enterprise model. This method gives an explicit representation of the business process logic and the relationships between the elements involved in the process. An execution-oriented integrated enterprise modeling system is proposed in combination with other enterprise views. The enterprise model can be established and executed dynamically in the actual environment due to the dynamic properties of the workflow model.

  7. Bayesian Network Based XP Process Modelling

    Directory of Open Access Journals (Sweden)

    Mohamed Abouelela

    2010-07-01

    Full Text Available A Bayesian Network based mathematical model has been used for modelling Extreme Programmingsoftware development process. The model is capable of predicting the expected finish time and theexpected defect rate for each XP release. Therefore, it can be used to determine the success/failure of anyXP Project. The model takes into account the effect of three XP practices, namely: Pair Programming,Test Driven Development and Onsite Customer practices. The model’s predictions were validated againsttwo case studies. Results show the precision of our model especially in predicting the project finish time.

  8. Model Based Testing for Agent Systems

    Science.gov (United States)

    Zhang, Zhiyong; Thangarajah, John; Padgham, Lin

    Although agent technology is gaining world wide popularity, a hindrance to its uptake is the lack of proper testing mechanisms for agent based systems. While many traditional software testing methods can be generalized to agent systems, there are many aspects that are different and which require an understanding of the underlying agent paradigm. In this paper we present certain aspects of a testing framework that we have developed for agent based systems. The testing framework is a model based approach using the design models of the Prometheus agent development methodology. In this paper we focus on model based unit testing and identify the appropriate units, present mechanisms for generating suitable test cases and for determining the order in which the units are to be tested, present a brief overview of the unit testing process and an example. Although we use the design artefacts from Prometheus the approach is suitable for any plan and event based agent system.

  9. Grey-theory based intrusion detection model

    Institute of Scientific and Technical Information of China (English)

    Qin Boping; Zhou Xianwei; Yang Jun; Song Cunyi

    2006-01-01

    To solve the problem that current intrusion detection model needs large-scale data in formulating the model in real-time use, an intrusion detection system model based on grey theory (GTIDS) is presented. Grey theory has merits of fewer requirements on original data scale, less limitation of the distribution pattern and simpler algorithm in modeling.With these merits GTIDS constructs model according to partial time sequence for rapid detect on intrusive act in secure system. In this detection model rate of false drop and false retrieval are effectively reduced through twice modeling and repeated detect on target data. Furthermore, GTIDS framework and specific process of modeling algorithm are presented. The affectivity of GTIDS is proved through emulated experiments comparing snort and next-generation intrusion detection expert system (NIDES) in SRI international.

  10. Springer handbook of model-based science

    CERN Document Server

    Bertolotti, Tommaso

    2017-01-01

    The handbook offers the first comprehensive reference guide to the interdisciplinary field of model-based reasoning. It highlights the role of models as mediators between theory and experimentation, and as educational devices, as well as their relevance in testing hypotheses and explanatory functions. The Springer Handbook merges philosophical, cognitive and epistemological perspectives on models with the more practical needs related to the application of this tool across various disciplines and practices. The result is a unique, reliable source of information that guides readers toward an understanding of different aspects of model-based science, such as the theoretical and cognitive nature of models, as well as their practical and logical aspects. The inferential role of models in hypothetical reasoning, abduction and creativity once they are constructed, adopted, and manipulated for different scientific and technological purposes is also discussed. Written by a group of internationally renowned experts in ...

  11. Econophysics of agent-based models

    CERN Document Server

    Aoyama, Hideaki; Chakrabarti, Bikas; Chakraborti, Anirban; Ghosh, Asim

    2014-01-01

    The primary goal of this book is to present the research findings and conclusions of physicists, economists, mathematicians and financial engineers working in the field of "Econophysics" who have undertaken agent-based modelling, comparison with empirical studies and related investigations. Most standard economic models assume the existence of the representative agent, who is “perfectly rational” and applies the utility maximization principle when taking action. One reason for this is the desire to keep models mathematically tractable: no tools are available to economists for solving non-linear models of heterogeneous adaptive agents without explicit optimization. In contrast, multi-agent models, which originated from statistical physics considerations, allow us to go beyond the prototype theories of traditional economics involving the representative agent. This book is based on the Econophys-Kolkata VII Workshop, at which many such modelling efforts were presented. In the book, leading researchers in the...

  12. Agent-based modelling of cholera diffusion

    NARCIS (Netherlands)

    Augustijn, Ellen-Wien; Doldersum, Tom; Useya, Juliana; Augustijn, Denie

    2016-01-01

    This paper introduces a spatially explicit agent-based simulation model for micro-scale cholera diffusion. The model simulates both an environmental reservoir of naturally occurring V. cholerae bacteria and hyperinfectious V. cholerae. Objective of the research is to test if runoff from open refuse

  13. Agent-based modelling of cholera diffusion

    NARCIS (Netherlands)

    Augustijn, Ellen-Wien; Doldersum, Tom; Useya, Juliana; Augustijn, Denie

    2016-01-01

    This paper introduces a spatially explicit agent-based simulation model for micro-scale cholera diffusion. The model simulates both an environmental reservoir of naturally occurring V.cholerae bacteria and hyperinfectious V. cholerae. Objective of the research is to test if runoff from open refuse d

  14. Agent-based modelling of cholera diffusion

    NARCIS (Netherlands)

    Augustijn-Beckers, Petronella; Doldersum, Tom; Useya, Juliana; Augustijn, Dionysius C.M.

    2016-01-01

    This paper introduces a spatially explicit agent-based simulation model for micro-scale cholera diffusion. The model simulates both an environmental reservoir of naturally occurring V.cholerae bacteria and hyperinfectious V. cholerae. Objective of the research is to test if runoff from open refuse

  15. New global ICT-based business models

    DEFF Research Database (Denmark)

    House Case The Nano Solar Case The Master Cat Case The Pitfalls Of The Blue Ocean Strategy - Implications Of "The Six Paths Framework" Network-Based Innovation - Combining Exploration and Exploitation? Innovating New Business Models in Inter-firm Collaboration NEW Global Business Models - What Did...

  16. Approximation Algorithms for Model-Based Diagnosis

    NARCIS (Netherlands)

    Feldman, A.B.

    2010-01-01

    Model-based diagnosis is an area of abductive inference that uses a system model, together with observations about system behavior, to isolate sets of faulty components (diagnoses) that explain the observed behavior, according to some minimality criterion. This thesis presents greedy approximation a

  17. Rule-based Modelling and Tunable Resolution

    Directory of Open Access Journals (Sweden)

    Russ Harmer

    2009-11-01

    Full Text Available We investigate the use of an extension of rule-based modelling for cellular signalling to create a structured space of model variants. This enables the incremental development of rule sets that start from simple mechanisms and which, by a gradual increase in agent and rule resolution, evolve into more detailed descriptions.

  18. Rule-based Modelling and Tunable Resolution

    CERN Document Server

    Harmer, Russ

    2009-01-01

    We investigate the use of an extension of rule-based modelling for cellular signalling to create a structured space of model variants. This enables the incremental development of rule sets that start from simple mechanisms and which, by a gradual increase in agent and rule resolution, evolve into more detailed descriptions.

  19. Approximation Algorithms for Model-Based Diagnosis

    NARCIS (Netherlands)

    Feldman, A.B.

    2010-01-01

    Model-based diagnosis is an area of abductive inference that uses a system model, together with observations about system behavior, to isolate sets of faulty components (diagnoses) that explain the observed behavior, according to some minimality criterion. This thesis presents greedy approximation a

  20. Mineral resources estimation based on block modeling

    Science.gov (United States)

    Bargawa, Waterman Sulistyana; Amri, Nur Ali

    2016-02-01

    The estimation in this paper uses three kinds of block models of nearest neighbor polygon, inverse distance squared and ordinary kriging. The techniques are weighting scheme which is based on the principle that block content is a linear combination of the grade data or the sample around the block being estimated. The case study in Pongkor area, here is gold-silver resource modeling that allegedly shaped of quartz vein as a hydrothermal process of epithermal type. Resources modeling includes of data entry, statistical and variography analysis of topography and geological model, the block model construction, estimation parameter, presentation model and tabulation of mineral resources. Skewed distribution, here isolated by robust semivariogram. The mineral resources classification generated in this model based on an analysis of the kriging standard deviation and number of samples which are used in the estimation of each block. Research results are used to evaluate the performance of OK and IDS estimator. Based on the visual and statistical analysis, concluded that the model of OK gives the estimation closer to the data used for modeling.

  1. Gradient based filtering of digital elevation models

    DEFF Research Database (Denmark)

    Knudsen, Thomas; Andersen, Rune Carbuhn

    We present a filtering method for digital terrain models (DTMs). The method is based on mathematical morphological filtering within gradient (slope) defined domains. The intention with the filtering procedure is to improbé the cartographic quality of height contours generated from a DTM based on ...... in the landscape are washed out and misrepresented....

  2. Gradient based filtering of digital elevation models

    DEFF Research Database (Denmark)

    Knudsen, Thomas; Andersen, Rune Carbuhn

    We present a filtering method for digital terrain models (DTMs). The method is based on mathematical morphological filtering within gradient (slope) defined domains. The intention with the filtering procedure is to improbé the cartographic quality of height contours generated from a DTM based...

  3. Information modelling and knowledge bases XXV

    CERN Document Server

    Tokuda, T; Jaakkola, H; Yoshida, N

    2014-01-01

    Because of our ever increasing use of and reliance on technology and information systems, information modelling and knowledge bases continue to be important topics in those academic communities concerned with data handling and computer science. As the information itself becomes more complex, so do the levels of abstraction and the databases themselves. This book is part of the series Information Modelling and Knowledge Bases, which concentrates on a variety of themes in the important domains of conceptual modeling, design and specification of information systems, multimedia information modelin

  4. Multiagent-Based Model For ESCM

    OpenAIRE

    Delia MARINCAS

    2011-01-01

    Web based applications for Supply Chain Management (SCM) are now a necessity for every company in order to meet the increasing customer demands, to face the global competition and to make profit. Multiagent-based approach is appropriate for eSCM because it shows many of the characteristics a SCM system should have. For this reason, we have proposed a multiagent-based eSCM model which configures a virtual SC, automates the SC activities: selling, purchasing, manufacturing, planning, inventory,...

  5. Agent-Based vs. Equation-based Epidemiological Models:A Model Selection Case Study

    Energy Technology Data Exchange (ETDEWEB)

    Sukumar, Sreenivas R [ORNL; Nutaro, James J [ORNL

    2012-01-01

    This paper is motivated by the need to design model validation strategies for epidemiological disease-spread models. We consider both agent-based and equation-based models of pandemic disease spread and study the nuances and complexities one has to consider from the perspective of model validation. For this purpose, we instantiate an equation based model and an agent based model of the 1918 Spanish flu and we leverage data published in the literature for our case- study. We present our observations from the perspective of each implementation and discuss the application of model-selection criteria to compare the risk in choosing one modeling paradigm to another. We conclude with a discussion of our experience and document future ideas for a model validation framework.

  6. [Intersticial lung disease as the sole manifestation of antisynthetase syndrome].

    Science.gov (United States)

    Monteiro, Paulo; Coutinho, Margarida; Machado, Pedro; Garcia, Jorge; Salvador, Maria João; Inês, Luís; Silva, Jorge; Malcata, Armando

    2009-01-01

    The authors report a clinical case of a woman who had a 3 years diagnosis of hipersensitivity pneumonitis based on intersticial lung disease without other manifestations. The diagnosis of antisynthetase syndrome was made three years after the initial symptoms upon the onset of systemic manifestations with articular involvement, myositis and determination of anti-PL 7 antibodies. In this syndrome, the isolated pulmonary involvement is rare.

  7. Flower solid modeling based on sketches

    Institute of Scientific and Technical Information of China (English)

    Zhan DING; Shu-chang XU; Xiu-zi YE; Yin ZHANG; San-yuan ZHANG

    2008-01-01

    In this paper we propose a method to model flowers of solid shape. Based on (Ijiri et al., 2005)'s method, we separate individual flower modeling and inflorescence modeling procedures into structure and geometry modeling. We incorporate interactive editing gestures to allow the user to edit structure parameters freely onto structure diagram. Furthermore, we use free-hand sketching techniques to allow users to create and edit 3D geometrical elements freely and easily. The final step is to automatically merge all independent 3D geometrical elements into a single waterproof mesh. Our experiments show that this solid modeling approach is promising. Using our approach, novice users can create vivid flower models easily and freely. The generated flower model is waterproof. It can have applications in visualization, animation, gaming, and toys and decorations if printed out on 3D rapid prototyping devices.

  8. New global ICT-based business models

    DEFF Research Database (Denmark)

    . Contents: The Theoretical History and Background of Business Models The Th eoretical Background of Business Model Innovation ICT - a Key Enabler in Innovating New Global Business Models The NEWGIBM Research Methodology The Analytical Model for NEWGIBM Industry Service - Technology Centre The KMD Case Smart...... House Case The Nano Solar Case The Master Cat Case The Pitfalls Of The Blue Ocean Strategy - Implications Of "The Six Paths Framework" Network-Based Innovation - Combining Exploration and Exploitation? Innovating New Business Models in Inter-firm Collaboration NEW Global Business Models - What Did......The New Global Business model (NEWGIBM) book describes the background, theory references, case studies, results and learning imparted by the NEWGIBM project, which is supported by ICT, to a research group during the period from 2005-2011. The book is a result of the efforts and the collaborative...

  9. Deformable surface modeling based on dual subdivision

    Institute of Scientific and Technical Information of China (English)

    WANG Huawei; SUN Hanqiu; QIN Kaihuai

    2005-01-01

    Based on dual Doo-Sabin subdivision and the corresponding parameterization, a modeling technique of deformable surfaces is presented in this paper. In the proposed model, all the dynamic parameters are computed in a unified way for both non-defective and defective subdivision matrices, and central differences are used to discretize the Lagrangian dynamics equation instead of backward differences. Moreover, a local scheme is developed to solve the dynamics equation approximately, thus the order of the linear equation is reduced greatly. Therefore, the proposed model is more efficient and faster than the existing dynamic models. It can be used for deformable surface design, interactive surface editing, medical imaging and simulation.

  10. Rule-based transformations for geometric modelling

    Directory of Open Access Journals (Sweden)

    Thomas Bellet

    2011-02-01

    Full Text Available The context of this paper is the use of formal methods for topology-based geometric modelling. Topology-based geometric modelling deals with objects of various dimensions and shapes. Usually, objects are defined by a graph-based topological data structure and by an embedding that associates each topological element (vertex, edge, face, etc. with relevant data as their geometric shape (position, curve, surface, etc. or application dedicated data (e.g. molecule concentration level in a biological context. We propose to define topology-based geometric objects as labelled graphs. The arc labelling defines the topological structure of the object whose topological consistency is then ensured by labelling constraints. Nodes have as many labels as there are different data kinds in the embedding. Labelling constraints ensure then that the embedding is consistent with the topological structure. Thus, topology-based geometric objects constitute a particular subclass of a category of labelled graphs in which nodes have multiple labels.

  11. Rule-based transformations for geometric modelling

    CERN Document Server

    Bellet, Thomas; Gall, Pascale Le; 10.4204/EPTCS.48.5

    2011-01-01

    The context of this paper is the use of formal methods for topology-based geometric modelling. Topology-based geometric modelling deals with objects of various dimensions and shapes. Usually, objects are defined by a graph-based topological data structure and by an embedding that associates each topological element (vertex, edge, face, etc.) with relevant data as their geometric shape (position, curve, surface, etc.) or application dedicated data (e.g. molecule concentration level in a biological context). We propose to define topology-based geometric objects as labelled graphs. The arc labelling defines the topological structure of the object whose topological consistency is then ensured by labelling constraints. Nodes have as many labels as there are different data kinds in the embedding. Labelling constraints ensure then that the embedding is consistent with the topological structure. Thus, topology-based geometric objects constitute a particular subclass of a category of labelled graphs in which nodes hav...

  12. Development of Ensemble Model Based Water Demand Forecasting Model

    Science.gov (United States)

    Kwon, Hyun-Han; So, Byung-Jin; Kim, Seong-Hyeon; Kim, Byung-Seop

    2014-05-01

    In recent years, Smart Water Grid (SWG) concept has globally emerged over the last decade and also gained significant recognition in South Korea. Especially, there has been growing interest in water demand forecast and optimal pump operation and this has led to various studies regarding energy saving and improvement of water supply reliability. Existing water demand forecasting models are categorized into two groups in view of modeling and predicting their behavior in time series. One is to consider embedded patterns such as seasonality, periodicity and trends, and the other one is an autoregressive model that is using short memory Markovian processes (Emmanuel et al., 2012). The main disadvantage of the abovementioned model is that there is a limit to predictability of water demands of about sub-daily scale because the system is nonlinear. In this regard, this study aims to develop a nonlinear ensemble model for hourly water demand forecasting which allow us to estimate uncertainties across different model classes. The proposed model is consist of two parts. One is a multi-model scheme that is based on combination of independent prediction model. The other one is a cross validation scheme named Bagging approach introduced by Brieman (1996) to derive weighting factors corresponding to individual models. Individual forecasting models that used in this study are linear regression analysis model, polynomial regression, multivariate adaptive regression splines(MARS), SVM(support vector machine). The concepts are demonstrated through application to observed from water plant at several locations in the South Korea. Keywords: water demand, non-linear model, the ensemble forecasting model, uncertainty. Acknowledgements This subject is supported by Korea Ministry of Environment as "Projects for Developing Eco-Innovation Technologies (GT-11-G-02-001-6)

  13. MEGen: A Physiologically Based Pharmacokinetic Model Generator

    Directory of Open Access Journals (Sweden)

    George D Loizou

    2011-11-01

    Full Text Available Physiologically based pharmacokinetic models are being used in an increasing number of different areas. These not only include the human safety assessment of pharmaceuticals, pesticides, biocides and environmental chemicals but also for food animal, wild mammal and avian risk assessment. The value of PBPK models is that they are tools for estimating tissue dosimetry by integrating in vitro and in vivo mechanistic, pharmacokinetic and toxicological information through their explicit mathematical description of important anatomical, physiological and biochemical determinants of chemical uptake, disposition and elimination. However, PBPK models are perceived as complex, data hungry, resource intensive and time consuming. In addition, model validation and verification are hindered by the relative complexity of the equations. To begin to address these issues a freely available web application for the rapid construction and documentation of bespoke PBPK models is under development. Here we present an overview of the current capabilities of MEGen, a model equation generator and parameter database and discuss future developments.

  14. Garner interference is not solely driven by stimulus uncertainty.

    Science.gov (United States)

    Burns, Devin M

    2016-12-01

    The speeded classification tasks popularized by Garner (1974), with their accompanying labels of separable and integral dimensions, have become the dominant paradigm for characterizing perceptual interactions between stimulus dimensions. Separable dimensions like color and shape can be selectively attended to at will, but integral dimensions like hue and brightness cannot. When classifying stimuli with respect to a single dimension, integral stimuli lead to faster performance in the baseline block, where only that single dimension varies, than in the filtering block, in which a second dimension is allowed to vary irrelevantly. No such difference is predicted for separable dimensions lead to no difference. The comparison between baseline and filtering confounds a change in the number of stimuli with a change in the number of variant dimensions. A new experimental condition is proposed utilizing three stimulus dimensions to hold the number of stimuli constant while introducing variance along a second irrelevant dimension. Data indicate that interference increases, suggesting that changes in the number of potential stimuli within a block are not necessary for Garner interference, in contrast to the accounts provided by extant quantitative models.

  15. Applying Model Checking to Generate Model-Based Integration Tests from Choreography Models

    Science.gov (United States)

    Wieczorek, Sebastian; Kozyura, Vitaly; Roth, Andreas; Leuschel, Michael; Bendisposto, Jens; Plagge, Daniel; Schieferdecker, Ina

    Choreography models describe the communication protocols between services. Testing of service choreographies is an important task for the quality assurance of service-based systems as used e.g. in the context of service-oriented architectures (SOA). The formal modeling of service choreographies enables a model-based integration testing (MBIT) approach. We present MBIT methods for our service choreography modeling approach called Message Choreography Models (MCM). For the model-based testing of service choreographies, MCMs are translated into Event-B models and used as input for our test generator which uses the model checker ProB.

  16. Record of high-pressure overprint in metamorphic soles of the Tavşanli zone, Western Anatolia

    Science.gov (United States)

    Plunder, Alexis; Agard, Philippe; Chopin, Christian; Okay, Aral

    2013-04-01

    Large obducted ophiolites correspond to the emplacement of dense oceanic lithosphere on top of a continent and thereby provide insights into rheological and thermal coupling between plates or fluid budgets. Obducted ophiolites thrust onto the continental margin of the Anatolide-Tauride block (Western Anatolia, south of the Izmir-Ankara suture zone) are dated through their metamorphic sole at ca. 90-95Ma and derive from the same intra-oceanic Neotethyan subduction. We herein focus on the metamorphic soles of the Tavşanlı zone, which show a variable high-pressure low-temperature (HP-LT) overprint of the initial amphibolitic metamorphic conditions (Önen & Hall, 1993; Dilek & Whitney, 1997; Okay et al, 1998). Systematic sampling was done in both the already studied areas as well as new locations. PT conditions were estimated at 8 kbar and 700°C for the amphibolitic stage with the assemblage hornblende + plagioclase ± garnet ± epidote. The HP-LT metamorphic overprint reached incipient blueschist to blueschist facies PT conditions. Development of the characteristic assemblage glaucophane + lawsonite yields PT estimates of >6-7 kbar and 300°C. The high-pressure stage is similar to the one observed for the underlying accretionary-complex unit of the Tavşanlı zone (Plunder et al, this meeting). This HP overprint was not observed in other obduction contexts such as Oman or New Caledonia but was documented in Fransciscan Complex amphibolites (Wakayabashi, 1990). The record of two metamorphic events can be understood as: (1) rapid cooling of the subduction zone after initiation and the exhumation of the metamorphic sole; (2) reburial after or during exhumation of the amphibolite initially welded at the base of the ophiolite. Several observations (i.e., lack of tectonic contact between the ophiolitic body and the metamorphic sole, PT estimates,...) point to cooling as the most likely hypothesis. Metamorphic soles allow to highlight: (1) the dynamics of obducted

  17. From Creatures of Habit to Goal-Directed Learners: Tracking the Developmental Emergence of Model-Based Reinforcement Learning.

    Science.gov (United States)

    Decker, Johannes H; Otto, A Ross; Daw, Nathaniel D; Hartley, Catherine A

    2016-06-01

    Theoretical models distinguish two decision-making strategies that have been formalized in reinforcement-learning theory. A model-based strategy leverages a cognitive model of potential actions and their consequences to make goal-directed choices, whereas a model-free strategy evaluates actions based solely on their reward history. Research in adults has begun to elucidate the psychological mechanisms and neural substrates underlying these learning processes and factors that influence their relative recruitment. However, the developmental trajectory of these evaluative strategies has not been well characterized. In this study, children, adolescents, and adults performed a sequential reinforcement-learning task that enabled estimation of model-based and model-free contributions to choice. Whereas a model-free strategy was apparent in choice behavior across all age groups, a model-based strategy was absent in children, became evident in adolescents, and strengthened in adults. These results suggest that recruitment of model-based valuation systems represents a critical cognitive component underlying the gradual maturation of goal-directed behavior.

  18. Spatial interactions in agent-based modeling

    CERN Document Server

    Ausloos, Marcel; Merlone, Ugo

    2014-01-01

    Agent Based Modeling (ABM) has become a widespread approach to model complex interactions. In this chapter after briefly summarizing some features of ABM the different approaches in modeling spatial interactions are discussed. It is stressed that agents can interact either indirectly through a shared environment and/or directly with each other. In such an approach, higher-order variables such as commodity prices, population dynamics or even institutions, are not exogenously specified but instead are seen as the results of interactions. It is highlighted in the chapter that the understanding of patterns emerging from such spatial interaction between agents is a key problem as much as their description through analytical or simulation means. The chapter reviews different approaches for modeling agents' behavior, taking into account either explicit spatial (lattice based) structures or networks. Some emphasis is placed on recent ABM as applied to the description of the dynamics of the geographical distribution o...

  19. Activity-based resource capability modeling

    Institute of Scientific and Technical Information of China (English)

    CHENG Shao-wu; XU Xiao-fei; WANG Gang; SUN Xue-dong

    2008-01-01

    To analyse and optimize a enterprise process in a wide scope, an activity-based method of modeling resource capabilities is presented. It models resource capabilities by means of the same structure as an activity, that is, resource capabilities are defined by input objects, actions and output objects. A set of activity-based re-source capability modeling rules and matching rules between an activity and a resource are introduced. This method can not only be used to describe capability of manufacturing tools, but also capability of persons and applications, etc. It unifies methods of modeling capability of all kinds of resources in an enterprise and supports the optimization of the resource allocation of a process.

  20. Graphical model construction based on evolutionary algorithms

    Institute of Scientific and Technical Information of China (English)

    Youlong YANG; Yan WU; Sanyang LIU

    2006-01-01

    Using Bayesian networks to model promising solutions from the current population of the evolutionary algorithms can ensure efficiency and intelligence search for the optimum. However, to construct a Bayesian network that fits a given dataset is a NP-hard problem, and it also needs consuming mass computational resources. This paper develops a methodology for constructing a graphical model based on Bayesian Dirichlet metric. Our approach is derived from a set of propositions and theorems by researching the local metric relationship of networks matching dataset. This paper presents the algorithm to construct a tree model from a set of potential solutions using above approach. This method is important not only for evolutionary algorithms based on graphical models, but also for machine learning and data mining.The experimental results show that the exact theoretical results and the approximations match very well.

  1. PV panel model based on datasheet values

    DEFF Research Database (Denmark)

    Sera, Dezso; Teodorescu, Remus; Rodriguez, Pedro

    2007-01-01

    This work presents the construction of a model for a PV panel using the single-diode five-parameters model, based exclusively on data-sheet parameters. The model takes into account the series and parallel (shunt) resistance of the panel. The equivalent circuit and the basic equations of the PV cell....../panel in Standard Test Conditions (STC) are shown, as well as the parameters extraction from the data-sheet values. The temperature dependence of the cell dark saturation current is expressed with an alternative formula, which gives better correlation with the datasheet values of the power temperature dependence....... Based on these equations, a PV panel model, which is able to predict the panel behavior in different temperature and irradiance conditions, is built and tested....

  2. Soil organic matter as sole indicator of soil degradation.

    Science.gov (United States)

    Obalum, S E; Chibuike, G U; Peth, S; Ouyang, Y

    2017-04-01

    Soil organic matter (SOM) is known to play vital roles in the maintenance and improvement of many soil properties and processes. These roles, which largely influence soil functions, are a pool of specific contributions of different components of SOM. The soil functions, in turn, normally define the level of soil degradation, viewed as quantifiable temporal changes in a soil that impairs its quality. This paper aims at providing a generalized assessment of the current state of knowledge on the usefulness of SOM in monitoring soil degradation, based on its influence on the physical, chemical and biological properties and processes of soils. Emphasis is placed particularly on the effect of SOM on soil structure and availability of plant nutrients. Although these properties are discussed separately, the soil system is of dynamic and interactive nature, and changes in one property will likely affect other soil properties as well. Thus, functions of SOM almost always affect various soil properties and processes and engage in multiple reactions. In view of its role in soil aggregation and erosion control, in availability of plant nutrients and in ameliorating other forms of soil degradation than erosion, SOM has proven to be an important indicator of soil degradation. It has been suggested, however, that rather than the absolute amount, temporal change and potential amount of SOM be considered in its use as indicator of soil degradation, and that SOM may not be an all-purpose indicator. Whilst SOM remains a candidate without substitute as long as a one-parameter indicator of soil degradation is needed, narrowing down to the use of its labile and microbial components could be more appropriate, since early detection is important in the control and management of soil degradation.

  3. Reaction-contingency based bipartite Boolean modelling

    Science.gov (United States)

    2013-01-01

    Background Intracellular signalling systems are highly complex, rendering mathematical modelling of large signalling networks infeasible or impractical. Boolean modelling provides one feasible approach to whole-network modelling, but at the cost of dequantification and decontextualisation of activation. That is, these models cannot distinguish between different downstream roles played by the same component activated in different contexts. Results Here, we address this with a bipartite Boolean modelling approach. Briefly, we use a state oriented approach with separate update rules based on reactions and contingencies. This approach retains contextual activation information and distinguishes distinct signals passing through a single component. Furthermore, we integrate this approach in the rxncon framework to support automatic model generation and iterative model definition and validation. We benchmark this method with the previously mapped MAP kinase network in yeast, showing that minor adjustments suffice to produce a functional network description. Conclusions Taken together, we (i) present a bipartite Boolean modelling approach that retains contextual activation information, (ii) provide software support for automatic model generation, visualisation and simulation, and (iii) demonstrate its use for iterative model generation and validation. PMID:23835289

  4. A Multiagent Based Model for Tactical Planning

    Science.gov (United States)

    2002-10-01

    Pub. Co. 1985. [10] Castillo, J.M. Aproximación mediante procedimientos de Inteligencia Artificial al planeamiento táctico. Doctoral Thesis...been developed under the same conceptual model and using similar Artificial Intelligence Tools. We use four different stimulus/response agents in...The conceptual model is built on base of the Agents theory. To implement the different agents we have used Artificial Intelligence techniques such

  5. GIS-Based Hydrogeological-Parameter Modeling

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    A regression model is proposed to relate the variation of water well depth with topographic properties (area and slope), the variation of hydraulic conductivity and vertical decay factor. The implementation of this model in GIS environment (ARC/TNFO) based on known water data and DEM is used to estimate the variation of hydraulic conductivity and decay factor of different lithoiogy units in watershed context.

  6. Integration of Simulink Models with Component-based Software Models

    DEFF Research Database (Denmark)

    Marian, Nicolae; Top, Søren

    2008-01-01

    of abstract system descriptions. Usually, in mechatronics systems, design proceeds by iterating model construction, model analysis, and model transformation. Constructing a MATLAB/Simulink model, a plant and controller behavior is simulated using graphical blocks to represent mathematical and logical...... of MATLAB/Simulink blocks to COMDES software components, both for continuous and discrete behaviour, and the transformation of the software system into the S-functions. The general aim of this work is the improvement of multi-disciplinary development of embedded systems with the focus on the relation...... constructs and process flow, then software code is generated. A Simulink model is a representation of the design or implementation of a physical system that satisfies a set of requirements. A software component-based system aims to organize system architecture and behaviour as a means of computation...

  7. Modeling the electromechanical and strain response of carbon nanotube-based nanocomposites

    Science.gov (United States)

    Lee, Bo Mi; Loh, Kenneth J.; Burton, Andrew R.; Loyola, Bryan R.

    2014-04-01

    Over the last few decades, carbon nanotube (CNT)-based thin films or nanocomposites have been widely investigated as a multifunctional material. The proposed applications extend beyond sensing, ultra-strong coatings, biomedical grafts, and energy harvesting, among others. In particular, thin films characterized by a percolated and random distribution of CNTs within a flexible polymeric matrix have been shown to change its electrical properties in response to applied strains. While a plethora of experimental work has been conducted, modeling their electromechanical response remains challenging. Furthermore, their design and optimization require the derivation of accurate electromechanical models that could predict thin film response to applied strains. Thus, the objective of this study is to implement a percolation-based piezoresistive model that could explain the underlying mechanisms for strain sensing. First, a percolation-based model with randomly distributed, straight CNTs was developed in MATLAB. Second, the number of CNTs within a unit area was varied to explore its influence on percolation probability. Then, to understand how the film's electrical properties respond to strain, two different models were implemented. Both models calculated the geometrical response of the film and CNTs due to applied uniaxial strains. The first model considered the fact that the electrical resistance of individual CNTs changed depending solely on its length between junctions. The other model further explored the idea of incorporating strain sensitivity of individual CNTs. The electromechanical responses and the strain sensitivities of the two models were compared by calculating how their bulk resistance varied due to applied tensile and compressive strains. The numerical model results were then qualitatively compared to experimental results reported in the literature.

  8. Atom-Role-Based Access Control Model

    Science.gov (United States)

    Cai, Weihong; Huang, Richeng; Hou, Xiaoli; Wei, Gang; Xiao, Shui; Chen, Yindong

    Role-based access control (RBAC) model has been widely recognized as an efficient access control model and becomes a hot research topic of information security at present. However, in the large-scale enterprise application environments, the traditional RBAC model based on the role hierarchy has the following deficiencies: Firstly, it is unable to reflect the role relationships in complicated cases effectively, which does not accord with practical applications. Secondly, the senior role unconditionally inherits all permissions of the junior role, thus if a user is under the supervisor role, he may accumulate all permissions, and this easily causes the abuse of permission and violates the least privilege principle, which is one of the main security principles. To deal with these problems, we, after analyzing permission types and role relationships, proposed the concept of atom role and built an atom-role-based access control model, called ATRBAC, by dividing the permission set of each regular role based on inheritance path relationships. Through the application-specific analysis, this model can well meet the access control requirements.

  9. Image-Based Multiresolution Implicit Object Modeling

    Directory of Open Access Journals (Sweden)

    Sarti Augusto

    2002-01-01

    Full Text Available We discuss two image-based 3D modeling methods based on a multiresolution evolution of a volumetric function′s level set. In the former method, the role of the level set implosion is to fuse ("sew" and "stitch" together several partial reconstructions (depth maps into a closed model. In the later, the level set′s implosion is steered directly by the texture mismatch between views. Both solutions share the characteristic of operating in an adaptive multiresolution fashion, in order to boost up computational efficiency and robustness.

  10. A multivalued knowledge-base model

    CERN Document Server

    Achs, Agnes

    2010-01-01

    The basic aim of our study is to give a possible model for handling uncertain information. This model is worked out in the framework of DATALOG. At first the concept of fuzzy Datalog will be summarized, then its extensions for intuitionistic- and interval-valued fuzzy logic is given and the concept of bipolar fuzzy Datalog is introduced. Based on these ideas the concept of multivalued knowledge-base will be defined as a quadruple of any background knowledge; a deduction mechanism; a connecting algorithm, and a function set of the program, which help us to determine the uncertainty levels of the results. At last a possible evaluation strategy is given.

  11. Physically based modeling and animation of tornado

    Institute of Scientific and Technical Information of China (English)

    LIU Shi-guang; WANG Zhang-ye; GONG Zheng; CHEN Fei-fei; PENG Qun-sheng

    2006-01-01

    Realistic modeling and rendering of dynamic tornado scene is recognized as a challenging task for researchers of computer graphics. In this paper a new physically based method for simulating and animating tornado scene is presented. We first propose a Two-Fluid model based on the physical theory of tornado, then we simulate the flow of tornado and its interaction with surrounding objects such as debris, etc. Taking the scattering and absorption of light by the participating media into account, the illumination effects of the tornado scene can be generated realistically. With the support of graphics hardware, various kinds of dynamic tornado scenes can be rendered at interactive rates.

  12. Model-based testing for embedded systems

    CERN Document Server

    Zander, Justyna; Mosterman, Pieter J

    2011-01-01

    What the experts have to say about Model-Based Testing for Embedded Systems: "This book is exactly what is needed at the exact right time in this fast-growing area. From its beginnings over 10 years ago of deriving tests from UML statecharts, model-based testing has matured into a topic with both breadth and depth. Testing embedded systems is a natural application of MBT, and this book hits the nail exactly on the head. Numerous topics are presented clearly, thoroughly, and concisely in this cutting-edge book. The authors are world-class leading experts in this area and teach us well-used

  13. Model Based Control of Reefer Container Systems

    DEFF Research Database (Denmark)

    Sørensen, Kresten Kjær

    This thesis is concerned with the development of model based control for the Star Cool refrigerated container (reefer) with the objective of reducing energy consumption. This project has been carried out under the Danish Industrial PhD programme and has been financed by Lodam together with the Da......This thesis is concerned with the development of model based control for the Star Cool refrigerated container (reefer) with the objective of reducing energy consumption. This project has been carried out under the Danish Industrial PhD programme and has been financed by Lodam together...

  14. SWIFT MODELLER: a Java based GUI for molecular modeling.

    Science.gov (United States)

    Mathur, Abhinav; Shankaracharya; Vidyarthi, Ambarish S

    2011-10-01

    MODELLER is command line argument based software which requires tedious formatting of inputs and writing of Python scripts which most people are not comfortable with. Also the visualization of output becomes cumbersome due to verbose files. This makes the whole software protocol very complex and requires extensive study of MODELLER manuals and tutorials. Here we describe SWIFT MODELLER, a GUI that automates formatting, scripting and data extraction processes and present it in an interactive way making MODELLER much easier to use than before. The screens in SWIFT MODELLER are designed keeping homology modeling in mind and their flow is a depiction of its steps. It eliminates the formatting of inputs, scripting processes and analysis of verbose output files through automation and makes pasting of the target sequence as the only prerequisite. Jmol (3D structure visualization tool) has been integrated into the GUI which opens and demonstrates the protein data bank files created by the MODELLER software. All files required and created by the software are saved in a folder named after the work instance's date and time of execution. SWIFT MODELLER lowers the skill level required for the software through automation of many of the steps in the original software protocol, thus saving an enormous amount of time per instance and making MODELLER very easy to work with.

  15. 29 CFR 500.73 - Required purchase of goods or services solely from any person prohibited.

    Science.gov (United States)

    2010-07-01

    ... DIVISION, DEPARTMENT OF LABOR REGULATIONS MIGRANT AND SEASONAL AGRICULTURAL WORKER PROTECTION Worker... migrant or seasonal agricultural worker to purchase goods or services solely from such farm labor... any person subject to this prohibition. Recruiting, Hiring and Providing Information to...

  16. AFSC/RACE/GAP/Nichol: Archival tag depth and temperature data from northern rock sole

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Depth data from archival tags on northern rock sole (Lepidopsetta polyxystra) were examined to assess whether fish used tidal currents to aid horizontal migration....

  17. Amyotrophic Lateral Sclerosis Presenting Respiratory Failure as the Sole Initial Manifestation

    Directory of Open Access Journals (Sweden)

    Fuyuki Tateno

    2014-08-01

    Full Text Available It is rare that amyotrophic lateral sclerosis (ALS presents with respiratory failure as the sole initial manifestation. A 72-year-old man with mild chronic obstructive pulmonary disease developed exertional dyspnea for 13 months. He then progressed to limb weakness that led to the diagnosis of ALS. Although rare, ALS can present with respiratory failure as the sole initial manifestation more than 1 year prior to limb weakness.

  18. Second Sourcing vs. Sole Sourcing with Capacity Investment and Asymmetric Information

    OpenAIRE

    Cuihong Li; Laurens G. Debo

    2009-01-01

    We study the decision of a manufacturer (the buyer), expecting new sourcing opportunities in the future, in selecting between sole- and second-sourcing strategies for a noncommodity component. In a sole-sourcing strategy, the buyer commits to sourcing from a single supplier (the incumbent) over the entire horizon. In a second-sourcing strategy, the buyer keeps the option open to source from a new supplier (the entrant) in the future. Supplier costs are private information, and the incumbent's...

  19. Activation of peripheral nerve fibers by electrical stimulation in the sole of the foot

    OpenAIRE

    Frahm, Ken Steffen; Mørch, Carsten Dahl; Grill, Warren M; Lubock, Nathan B; Hennings, Kristian; Andersen, Ole Kæseler

    2013-01-01

    Background Human nociceptive withdrawal reflexes (NWR) can be evoked by electrical stimulation applied to the sole of the foot. However, elicitation of NWRs is highly site dependent, and NWRs are especially difficult to elicit at the heel. The aim of the present study was to investigate potential peripheral mechanisms for any site dependent differences in reflex thresholds. Results The first part of the study investigated the neural innervation in different sites of the sole of the foot using...

  20. Entropy-based portfolio models: Practical issues

    Science.gov (United States)

    Shirazi, Yasaman Izadparast; Sabiruzzaman, Md.; Hamzah, Nor Aishah

    2015-10-01

    Entropy is a nonparametric alternative of variance and has been used as a measure of risk in portfolio analysis. In this paper, the computation of entropy risk for a given set of data is discussed with illustration. A comparison between entropy-based portfolio models is made. We propose a natural extension of the mean entropy portfolio to make it more general and diversified. In terms of performance, this new model is similar to the mean-entropy portfolio when applied to real and simulated data, and offers higher return if no constraint is set for the desired return; also it is found to be the most diversified portfolio model.

  1. Model Predictive Control based on Finite Impulse Response Models

    DEFF Research Database (Denmark)

    Prasath, Guru; Jørgensen, John Bagterp

    2008-01-01

    We develop a regularized l2 finite impulse response (FIR) predictive controller with input and input-rate constraints. Feedback is based on a simple constant output disturbance filter. The performance of the predictive controller in the face of plant-model mismatch is investigated by simulations...

  2. Incident Duration Modeling Using Flexible Parametric Hazard-Based Models

    Directory of Open Access Journals (Sweden)

    Ruimin Li

    2014-01-01

    Full Text Available Assessing and prioritizing the duration time and effects of traffic incidents on major roads present significant challenges for road network managers. This study examines the effect of numerous factors associated with various types of incidents on their duration and proposes an incident duration prediction model. Several parametric accelerated failure time hazard-based models were examined, including Weibull, log-logistic, log-normal, and generalized gamma, as well as all models with gamma heterogeneity and flexible parametric hazard-based models with freedom ranging from one to ten, by analyzing a traffic incident dataset obtained from the Incident Reporting and Dispatching System in Beijing in 2008. Results show that different factors significantly affect different incident time phases, whose best distributions were diverse. Given the best hazard-based models of each incident time phase, the prediction result can be reasonable for most incidents. The results of this study can aid traffic incident management agencies not only in implementing strategies that would reduce incident duration, and thus reduce congestion, secondary incidents, and the associated human and economic losses, but also in effectively predicting incident duration time.

  3. Incident duration modeling using flexible parametric hazard-based models.

    Science.gov (United States)

    Li, Ruimin; Shang, Pan

    2014-01-01

    Assessing and prioritizing the duration time and effects of traffic incidents on major roads present significant challenges for road network managers. This study examines the effect of numerous factors associated with various types of incidents on their duration and proposes an incident duration prediction model. Several parametric accelerated failure time hazard-based models were examined, including Weibull, log-logistic, log-normal, and generalized gamma, as well as all models with gamma heterogeneity and flexible parametric hazard-based models with freedom ranging from one to ten, by analyzing a traffic incident dataset obtained from the Incident Reporting and Dispatching System in Beijing in 2008. Results show that different factors significantly affect different incident time phases, whose best distributions were diverse. Given the best hazard-based models of each incident time phase, the prediction result can be reasonable for most incidents. The results of this study can aid traffic incident management agencies not only in implementing strategies that would reduce incident duration, and thus reduce congestion, secondary incidents, and the associated human and economic losses, but also in effectively predicting incident duration time.

  4. Designing Network-based Business Model Ontology

    DEFF Research Database (Denmark)

    Hashemi Nekoo, Ali Reza; Ashourizadeh, Shayegheh; Zarei, Behrouz

    2015-01-01

    Survival on dynamic environment is not achieved without a map. Scanning and monitoring of the market show business models as a fruitful tool. But scholars believe that old-fashioned business models are dead; as they are not included the effect of internet and network in themselves. This paper...... is going to propose e-business model ontology from the network point of view and its application in real world. The suggested ontology for network-based businesses is composed of individuals` characteristics and what kind of resources they own. also, their connections and pre-conceptions of connections...... such as shared-mental model and trust. However, it mostly covers previous business model elements. To confirm the applicability of this ontology, it has been implemented in business angel network and showed how it works....

  5. Haptics-based dynamic implicit solid modeling.

    Science.gov (United States)

    Hua, Jing; Qin, Hong

    2004-01-01

    This paper systematically presents a novel, interactive solid modeling framework, Haptics-based Dynamic Implicit Solid Modeling, which is founded upon volumetric implicit functions and powerful physics-based modeling. In particular, we augment our modeling framework with a haptic mechanism in order to take advantage of additional realism associated with a 3D haptic interface. Our dynamic implicit solids are semi-algebraic sets of volumetric implicit functions and are governed by the principles of dynamics, hence responding to sculpting forces in a natural and predictable manner. In order to directly manipulate existing volumetric data sets as well as point clouds, we develop a hierarchical fitting algorithm to reconstruct and represent discrete data sets using our continuous implicit functions, which permit users to further design and edit those existing 3D models in real-time using a large variety of haptic and geometric toolkits, and visualize their interactive deformation at arbitrary resolution. The additional geometric and physical constraints afford more sophisticated control of the dynamic implicit solids. The versatility of our dynamic implicit modeling enables the user to easily modify both the geometry and the topology of modeled objects, while the inherent physical properties can offer an intuitive haptic interface for direct manipulation with force feedback.

  6. Effects of shoe sole hardness on plantar pressure and comfort in older people with forefoot pain.

    Science.gov (United States)

    Lane, Tamara J; Landorf, Karl B; Bonanno, Daniel R; Raspovic, Anita; Menz, Hylton B

    2014-01-01

    Plantar forefoot pain is common in older people and is related to increased peak pressures under the foot during gait. Variations in the hardness of the shoe sole may therefore influence both the magnitude of loading under the foot and the perceived comfort of the shoe in this population. The aim of this investigation was to determine the effect of varying shoe sole hardness on plantar pressures and comfort in older people with forefoot pain. In-shoe plantar pressures under the forefoot, midfoot and rearfoot were recorded from 35 older people (mean age 73.2, SD 4.5 years) with current or previous forefoot pain using the pedar-X(®) system. Participants walked at their normal comfortable speed along an 8m walkway in shoes with three different levels of sole hardness: soft (Shore A25), medium (Shore A40) and hard (Shore A58). Shoe comfort was measured on a 100mm visual analogue scale. There were statistically significant differences in peak pressure of between 5% and 23% across the forefoot, midfoot and rearfoot (phard-soled shoe registered the highest peak pressures and the soft-soled shoe the lowest peak pressures. However, no differences in comfort scores across the three shoe conditions were observed. These findings demonstrate that as shoe sole hardness increases, plantar pressure increases, however this does not appear to have a significant effect on shoe comfort.

  7. ALGORITHMS FOR THE PROGRAMMING OF FOOTWEAR SOLES MOULDS ON WORKING POSTS OF INJECTION MACHINES

    Directory of Open Access Journals (Sweden)

    LUCA Cornelia

    2014-05-01

    Full Text Available The moulds stock necessary for realization in rhythmically conditions, a certain volume of footwear soles depends on some criterions such as: the range of soles for footwear volume daily realized, the sizes structure of those soles for footwear and, respectively, the sizes tally, the technological cycle for an used mould depending on the equipment efficiency, the provide necessity of spare moulds, the using and fixing conditions etc. From the efficiency point of view, the equipments may have two working posts, or more working posts (always, an even number, as 6, 12, 24, 40 posts. Footwear soles manufacturing takes into account the percentage distribution of the size numbers of the size series. When o portative assembly is used for the manufacturing of the footwear soles using the injection with “n” working posts, it is very important an optimum distribution of the working posts. The disadvantages of these equipments are the situations of the no equilibrium programming of the moulds, so that, in one time, some working posts spread out of the work. The paper presents some practical and theoretical solutions for moulds stock programming in portative assembly for footwear soles injection, so that an optimum equilibrium degree of the working posts will obtain

  8. Model-Based Power Plant Master Control

    Energy Technology Data Exchange (ETDEWEB)

    Boman, Katarina; Thomas, Jean; Funkquist, Jonas

    2010-08-15

    The main goal of the project has been to evaluate the potential of a coordinated master control for a solid fuel power plant in terms of tracking capability, stability and robustness. The control strategy has been model-based predictive control (MPC) and the plant used in the case study has been the Vattenfall power plant Idbaecken in Nykoeping. A dynamic plant model based on nonlinear physical models was used to imitate the true plant in MATLAB/SIMULINK simulations. The basis for this model was already developed in previous Vattenfall internal projects, along with a simulation model of the existing control implementation with traditional PID controllers. The existing PID control is used as a reference performance, and it has been thoroughly studied and tuned in these previous Vattenfall internal projects. A turbine model was developed with characteristics based on the results of steady-state simulations of the plant using the software EBSILON. Using the derived model as a representative for the actual process, an MPC control strategy was developed using linearization and gain-scheduling. The control signal constraints (rate of change) and constraints on outputs were implemented to comply with plant constraints. After tuning the MPC control parameters, a number of simulation scenarios were performed to compare the MPC strategy with the existing PID control structure. The simulation scenarios also included cases highlighting the robustness properties of the MPC strategy. From the study, the main conclusions are: - The proposed Master MPC controller shows excellent set-point tracking performance even though the plant has strong interactions and non-linearity, and the controls and their rate of change are bounded. - The proposed Master MPC controller is robust, stable in the presence of disturbances and parameter variations. Even though the current study only considered a very small number of the possible disturbances and modelling errors, the considered cases are

  9. Frequency response function-based model updating using Kriging model

    Science.gov (United States)

    Wang, J. T.; Wang, C. J.; Zhao, J. P.

    2017-03-01

    An acceleration frequency response function (FRF) based model updating method is presented in this paper, which introduces Kriging model as metamodel into the optimization process instead of iterating the finite element analysis directly. The Kriging model is taken as a fast running model that can reduce solving time and facilitate the application of intelligent algorithms in model updating. The training samples for Kriging model are generated by the design of experiment (DOE), whose response corresponds to the difference between experimental acceleration FRFs and its counterpart of finite element model (FEM) at selected frequency points. The boundary condition is taken into account, and a two-step DOE method is proposed for reducing the number of training samples. The first step is to select the design variables from the boundary condition, and the selected variables will be passed to the second step for generating the training samples. The optimization results of the design variables are taken as the updated values of the design variables to calibrate the FEM, and then the analytical FRFs tend to coincide with the experimental FRFs. The proposed method is performed successfully on a composite structure of honeycomb sandwich beam, after model updating, the analytical acceleration FRFs have a significant improvement to match the experimental data especially when the damping ratios are adjusted.

  10. Model based development of engine control algorithms

    NARCIS (Netherlands)

    Dekker, H.J.; Sturm, W.L.

    1996-01-01

    Model based development of engine control systems has several advantages. The development time and costs are strongly reduced because much of the development and optimization work is carried out by simulating both engine and control system. After optimizing the control algorithm it can be executed b

  11. Agent based computational model of trust

    NARCIS (Netherlands)

    A. Gorobets (Alexander); B. Nooteboom (Bart)

    2004-01-01

    textabstractThis paper employs the methodology of Agent-Based Computational Economics (ACE) to investigate under what conditions trust can be viable in markets. The emergence and breakdown of trust is modeled in a context of multiple buyers and suppliers. Agents adapt their trust in a partner, the w

  12. Néron Models and Base Change

    DEFF Research Database (Denmark)

    Halle, Lars Halvard; Nicaise, Johannes

    on Néron component groups, Edixhoven’s filtration and the base change conductor of Chai and Yu, and we study these invariants using various techniques such as models of curves, sheaves on Grothendieck sites and non-archimedean uniformization. We then apply our results to the study of motivic zeta functions...

  13. What's Missing in Model-Based Teaching

    Science.gov (United States)

    Khan, Samia

    2011-01-01

    In this study, the author investigated how four science teachers employed model-based teaching (MBT) over a 1-year period. The purpose of the research was to develop a baseline of the fundamental and specific dimensions of MBT that are present and absent in science teaching. Teacher interviews, classroom observations, and pre and post-student…

  14. Prototype-based models in machine learning

    NARCIS (Netherlands)

    Biehl, Michael; Hammer, Barbara; Villmann, Thomas

    2016-01-01

    An overview is given of prototype-based models in machine learning. In this framework, observations, i.e., data, are stored in terms of typical representatives. Together with a suitable measure of similarity, the systems can be employed in the context of unsupervised and supervised analysis of poten

  15. CEAI: CCM based Email Authorship Identification Model

    DEFF Research Database (Denmark)

    Nizamani, Sarwat; Memon, Nasrullah

    2013-01-01

    content features. It is observed that the use of such features in the authorship identification process has a positive impact on the accuracy of the authorship identification task. We performed experiments to justify our arguments and compared the results with other base line models. Experimental results...

  16. Prototype-based models in machine learning

    NARCIS (Netherlands)

    Biehl, Michael; Hammer, Barbara; Villmann, Thomas

    2016-01-01

    An overview is given of prototype-based models in machine learning. In this framework, observations, i.e., data, are stored in terms of typical representatives. Together with a suitable measure of similarity, the systems can be employed in the context of unsupervised and supervised analysis of

  17. Port-based modeling of mechatronic systems

    NARCIS (Netherlands)

    Breedveld, Peter C.

    2004-01-01

    Many engineering activities, including mechatronic design, require that a multidomain or ‘multi-physics’ system and its control system be designed as an integrated system. This contribution discusses the background and tools for a port-based approach to integrated modeling and simulation of physical

  18. Sandboxes for Model-Based Inquiry

    Science.gov (United States)

    Brady, Corey; Holbert, Nathan; Soylu, Firat; Novak, Michael; Wilensky, Uri

    2015-01-01

    In this article, we introduce a class of constructionist learning environments that we call "Emergent Systems Sandboxes" ("ESSs"), which have served as a centerpiece of our recent work in developing curriculum to support scalable model-based learning in classroom settings. ESSs are a carefully specified form of virtual…

  19. Analysis of phenotypic and genetic parameters for growthrelated traits in the half smooth tongue sole, Cynoglossus semilaevis

    Science.gov (United States)

    Liu, Feng; Li, Yangzhen; Du, Min; Shao, Changwei; Chen, Songlin

    2016-01-01

    Phenotypic and genetic parameters for growth-related traits in the half-smooth tongue sole, Cynoglossus semilaevis, were estimated in 22 full-sib families produced by normal and neo-male breeding stocks. As phenotypic males with female genotypes, neo-males are harmful in C. semilaevis aquaculture because they reduce overall production. The present study evaluated the difference in the growth-related traits: total length (TL), body weight (BW) and square root of body weight (SQ_BW) at the age of 570 days between normal and neo-male offspring (neo-males used as male parents). The difference in the proportion of females between normal and neo-male offspring was also assessed. Based on the linear mixed model, restricted maximum likelihood (REML) and best linear unbiased prediction (BLUP) were used to estimate various (co)variance components and estimated breeding values (EBVs) of growth-related traits. As a result, all the mean values of the three studied traits were significantly larger in normal offspring than in neo-male offspring. Additionally, the female proportion was significantly larger in normal offspring than in neo-male offspring. Heritability was 0.128±0.066 2 for TL, 0.128±0.065 5 for BW and 0.132±0.062 9 for SQ_BW, all of which were low level heritabilities. The correlation coefficients of EBVs and phenotypic values of the target traits were 0.516 for TL, 0.524 for BW and 0.506 for SQ_BW, all of which were highly significant ( P standard errors (0.063-0.123 for genotype, and 0.010-0.018 for phenotype). Compared with normal offspring, neo-male offspring have lower breeding values for each studied trait through EBVs comparison. Therefore, neo-male offspring should not be used as broodstock in a C. semilaevis breeding programs.

  20. Deriving Framework Usages Based on Behavioral Models

    Science.gov (United States)

    Zenmyo, Teruyoshi; Kobayashi, Takashi; Saeki, Motoshi

    One of the critical issue in framework-based software development is a huge introduction cost caused by technical gap between developers and users of frameworks. This paper proposes a technique for deriving framework usages to implement a given requirements specification. By using the derived usages, the users can use the frameworks without understanding the framework in detail. Requirements specifications which describe definite behavioral requirements cannot be related to frameworks in as-is since the frameworks do not have definite control structure so that the users can customize them to suit given requirements specifications. To cope with this issue, a new technique based on satisfiability problems (SAT) is employed to derive the control structures of the framework model. In the proposed technique, requirements specifications and frameworks are modeled based on Labeled Transition Systems (LTSs) with branch conditions represented by predicates. Truth assignments of the branch conditions in the framework models are not given initially for representing the customizable control structure. The derivation of truth assignments of the branch conditions is regarded as the SAT by assuming relations between termination states of the requirements specification model and ones of the framework model. This derivation technique is incorporated into a technique we have proposed previously for relating actions of requirements specifications to ones of frameworks. Furthermore, this paper discuss a case study of typical use cases in e-commerce systems.

  1. Introducing Waqf Based Takaful Model in India

    Directory of Open Access Journals (Sweden)

    Syed Ahmed Salman

    2014-03-01

    Full Text Available Objective – Waqf is a unique feature of the socioeconomic system of Islam in a multi- religious and developing country like India. India is a rich country with waqf assets. The history of waqf in India can be traced back to 800 years ago. Most of the researchers, suggest how waqf can be used a tool to mitigate the poverty of Muslims. India has the third highest Muslim population after Indonesia and Pakistan. However, the majority of Muslims belong to the low income group and they are in need of help. It is believed that waqf can be utilized for the betterment of Indian Muslim community. Among the available uses of waqf assets, the main objective of this paper is to introduce waqf based takaful model in India. In addition, how this proposed model can be adopted in India is highlighted.Methods – Library research is applied since this paper relies on secondary data by thoroughlyreviewing the most relevant literature.Result – India as a rich country with waqf assets should fully utilize the resources to help the Muslims through takaful.Conclusion – In this study, we have proposed waqf based takaful model with the combination of the concepts mudarabah and wakalah for India. We recommend this model based on the background of the  country and situations. Since we have not tested the viability of this model in India, future research should be continued on this testing.Keywords : Wakaf, Takaful, Kemiskinan dan India

  2. Statistical Seasonal Sea Surface based Prediction Model

    Science.gov (United States)

    Suarez, Roberto; Rodriguez-Fonseca, Belen; Diouf, Ibrahima

    2014-05-01

    The interannual variability of the sea surface temperature (SST) plays a key role in the strongly seasonal rainfall regime on the West African region. The predictability of the seasonal cycle of rainfall is a field widely discussed by the scientific community, with results that fail to be satisfactory due to the difficulty of dynamical models to reproduce the behavior of the Inter Tropical Convergence Zone (ITCZ). To tackle this problem, a statistical model based on oceanic predictors has been developed at the Universidad Complutense of Madrid (UCM) with the aim to complement and enhance the predictability of the West African Monsoon (WAM) as an alternative to the coupled models. The model, called S4CAST (SST-based Statistical Seasonal Forecast) is based on discriminant analysis techniques, specifically the Maximum Covariance Analysis (MCA) and Canonical Correlation Analysis (CCA). Beyond the application of the model to the prediciton of rainfall in West Africa, its use extends to a range of different oceanic, atmospheric and helth related parameters influenced by the temperature of the sea surface as a defining factor of variability.

  3. Unifying Model-Based and Reactive Programming within a Model-Based Executive

    Science.gov (United States)

    Williams, Brian C.; Gupta, Vineet; Norvig, Peter (Technical Monitor)

    1999-01-01

    Real-time, model-based, deduction has recently emerged as a vital component in AI's tool box for developing highly autonomous reactive systems. Yet one of the current hurdles towards developing model-based reactive systems is the number of methods simultaneously employed, and their corresponding melange of programming and modeling languages. This paper offers an important step towards unification. We introduce RMPL, a rich modeling language that combines probabilistic, constraint-based modeling with reactive programming constructs, while offering a simple semantics in terms of hidden state Markov processes. We introduce probabilistic, hierarchical constraint automata (PHCA), which allow Markov processes to be expressed in a compact representation that preserves the modularity of RMPL programs. Finally, a model-based executive, called Reactive Burton is described that exploits this compact encoding to perform efficIent simulation, belief state update and control sequence generation.

  4. Agent Based Modeling Applications for Geosciences

    Science.gov (United States)

    Stein, J. S.

    2004-12-01

    Agent-based modeling techniques have successfully been applied to systems in which complex behaviors or outcomes arise from varied interactions between individuals in the system. Each individual interacts with its environment, as well as with other individuals, by following a set of relatively simple rules. Traditionally this "bottom-up" modeling approach has been applied to problems in the fields of economics and sociology, but more recently has been introduced to various disciplines in the geosciences. This technique can help explain the origin of complex processes from a relatively simple set of rules, incorporate large and detailed datasets when they exist, and simulate the effects of extreme events on system-wide behavior. Some of the challenges associated with this modeling method include: significant computational requirements in order to keep track of thousands to millions of agents, methods and strategies of model validation are lacking, as is a formal methodology for evaluating model uncertainty. Challenges specific to the geosciences, include how to define agents that control water, contaminant fluxes, climate forcing and other physical processes and how to link these "geo-agents" into larger agent-based simulations that include social systems such as demographics economics and regulations. Effective management of limited natural resources (such as water, hydrocarbons, or land) requires an understanding of what factors influence the demand for these resources on a regional and temporal scale. Agent-based models can be used to simulate this demand across a variety of sectors under a range of conditions and determine effective and robust management policies and monitoring strategies. The recent focus on the role of biological processes in the geosciences is another example of an area that could benefit from agent-based applications. A typical approach to modeling the effect of biological processes in geologic media has been to represent these processes in

  5. Entropy Based Modelling for Estimating Demographic Trends.

    Directory of Open Access Journals (Sweden)

    Guoqi Li

    Full Text Available In this paper, an entropy-based method is proposed to forecast the demographical changes of countries. We formulate the estimation of future demographical profiles as a constrained optimization problem, anchored on the empirically validated assumption that the entropy of age distribution is increasing in time. The procedure of the proposed method involves three stages, namely: 1 Prediction of the age distribution of a country's population based on an "age-structured population model"; 2 Estimation the age distribution of each individual household size with an entropy-based formulation based on an "individual household size model"; and 3 Estimation the number of each household size based on a "total household size model". The last stage is achieved by projecting the age distribution of the country's population (obtained in stage 1 onto the age distributions of individual household sizes (obtained in stage 2. The effectiveness of the proposed method is demonstrated by feeding real world data, and it is general and versatile enough to be extended to other time dependent demographic variables.

  6. Cooperation among liquefied natural gas suppliers. Is rationalization the sole objective?

    Energy Technology Data Exchange (ETDEWEB)

    Massol, Olivier [Center for Economics and Management, IFP School, 228-232 av. Napoleon Bonaparte, F-92852 Rueil-Malmaison (France); Department of Economics, City University, Northampton Square, London EC1V 0HB (United Kingdom); Tchung-Ming, Stephane [Economic Studies Division, IFP, 1-4 av. de Bois-Preau, F-92852 Rueil Malmaison (France); CREDEN, Universite Montpellier I, Av. de la mer, BP 9606, F-34054, Montpellier (France)

    2010-07-15

    This paper examines the development of cooperative strategies between countries exporting Liquefied Natural Gas (LNG) and members of the Gas Exporting Countries Forum (GECF). This economic study focuses specifically on an often-raised scenario: the emergence of a cooperative approach designed with the sole aim of logistic rationalization, and which would not have any effect on LNG prices. We first assess the annual gains that may result from this market-power-free cooperative approach using a simple static transportation model. The numerical results obtained suggest that, in the absence of a gain redistribution policy, this cooperative strategy will probably not be adopted because cooperation would not be a rational move for some exporters. The problem of gain sharing is then formulated using cooperative game theory concepts. Several gain-sharing methods have been studied, including the Shapley value and various nucleolus-inspired concepts. Our results suggest that the choice of a redistribution policy appears relatively restricted. Out of the methods studied, only one - per capita nucleolus - satisfies two key requirements. core belonging and monotonicity (in the aggregate). Lastly, we look at how cooperation may give rise to a coordination cost and try to determine the maximum amount of this cost. In view of the low level of this amount and the relative complexity of the sharing method implemented, we consider that the credibility of a logistic cooperation scenario exempt from market power should be reappraised. (author)

  7. Family-Based Model Checking Without a Family-Based Model Checker

    DEFF Research Database (Denmark)

    Dimovski, Aleksandar; Al-Sibahi, Ahmad Salim; Brabrand, Claus

    2015-01-01

    (systems with variability), specialized family-based model checking algorithms allow efficient verification of multiple variants, simultaneously. These algorithms scale much better than ``brute force'' verification of individual systems, one-by-one. Nevertheless, they can deal with only very small...... variational models. We address two key problems of family-based model checking. First, we improve scalability by introducing abstractions that simplify variability. Second, we reduce the burden of maintaining specialized family-based model checkers, by showing how the presented variability abstractions can...... be used to model-check variational models using the standard version of (single system) SPIN. The abstractions are first defined as Galois connections on semantic domains. We then show how to translate them into syntactic source-to-source transformations on variational models. This allows the use of SPIN...

  8. Mesoscopic model of actin-based propulsion.

    Directory of Open Access Journals (Sweden)

    Jie Zhu

    Full Text Available Two theoretical models dominate current understanding of actin-based propulsion: microscopic polymerization ratchet model predicts that growing and writhing actin filaments generate forces and movements, while macroscopic elastic propulsion model suggests that deformation and stress of growing actin gel are responsible for the propulsion. We examine both experimentally and computationally the 2D movement of ellipsoidal beads propelled by actin tails and show that neither of the two models can explain the observed bistability of the orientation of the beads. To explain the data, we develop a 2D hybrid mesoscopic model by reconciling these two models such that individual actin filaments undergoing nucleation, elongation, attachment, detachment and capping are embedded into the boundary of a node-spring viscoelastic network representing the macroscopic actin gel. Stochastic simulations of this 'in silico' actin network show that the combined effects of the macroscopic elastic deformation and microscopic ratchets can explain the observed bistable orientation of the actin-propelled ellipsoidal beads. To test the theory further, we analyze observed distribution of the curvatures of the trajectories and show that the hybrid model's predictions fit the data. Finally, we demonstrate that the model can explain both concave-up and concave-down force-velocity relations for growing actin networks depending on the characteristic time scale and network recoil. To summarize, we propose that both microscopic polymerization ratchets and macroscopic stresses of the deformable actin network are responsible for the force and movement generation.

  9. PARTICIPATION BASED MODEL OF SHIP CREW MANAGEMENT

    Directory of Open Access Journals (Sweden)

    Toni Bielić

    2014-10-01

    Full Text Available 800x600 This paper analyse the participation - based model on board the ship as possibly optimal leadership model existing in the shipping industry with accent on decision - making process. In the paper authors have tried to define master’s behaviour model and management style identifying drawbacks and disadvantages of vertical, pyramidal organization with master on the top. Paper describes efficiency of decision making within team organization and optimization of a ship’s organisation by introducing teamwork on board the ship. Three examples of the ship’s accidents are studied and evaluated through “Leader - participation” model. The model of participation based management as a model of the teamwork has been applied in studying the cause - and - effect of accidents with the critical review of the communication and managing the human resources on a ship. The results have showed that the cause of all three accidents is the autocratic behaviour of the leaders and lack of communication within teams. Normal 0 21 false false false HR X-NONE X-NONE MicrosoftInternetExplorer4

  10. Mandarin Pronunciation Modeling Based on CASS Corpus

    Institute of Scientific and Technical Information of China (English)

    郑方; 宋战江; Pascale Fung; William Byrne

    2002-01-01

    The pronunciation variability is an important issue that must be faced with when developing practical automatic spontaneous speech recognition systems. In this paper, the factors that may affect the recognition performance are analyzed, including those specific to the Chinese language. By studying the INITIAL/FINAL (IF) characteristics of Chinese language and developing the Bayesian equation, the concepts of generalized INITIAL/FINAL (GIF) and generalized syllable (GS), the GIF modeling and the IF-GIF modeling, as well as the contextdependent pronunciation weighting, are proposed based on a well phonetically transcribed seed database. By using these methods, the Chinese syllable error rate (SER) is reduced by 6.3%and 4.2% compared with the GIF modeling and IF modeling respectively when the language model, such as syllable or word N-gram, is not used. The effectiveness of these methods is also proved when more data without the phonetic transcription are used to refine the acoustic model using the proposed iterative forced-alignment based transcribing (IFABT) method, achieving a 5.7% SER reduction.

  11. Modeling Leaves Based on Real Image

    Institute of Scientific and Technical Information of China (English)

    CAO Yu-kun; LI Yun-feng; ZHU Qing-sheng; LIU Yin-bin

    2004-01-01

    Plants have complex structures. The shape of a plant component is vital for capturing the characteristics of a species. One of the challenges in computer graphics is to create geometry of objects in an intuitive and direct way while allowing interactive manipulation of the resulting shapes. In this paper,an interactive method for modeling leaves based on real image is proposed using biological data for individual plants. The modeling process begins with a one-dimensional analogue of implicit surfaces,from which a 2D silhouette of a leaf is generated based on image segmentation. The silhouette skeleton is thus obtained. Feature parameters of the leaf are extracted based on biologically experimental data, and the obtained leaf structure is then modified by comparing the synthetic result with the real leaf so as to make the leaf structure more realistic. Finally, the leaf mesh is constructed by sweeps.

  12. Multiagent-Based Model For ESCM

    Directory of Open Access Journals (Sweden)

    Delia MARINCAS

    2011-01-01

    Full Text Available Web based applications for Supply Chain Management (SCM are now a necessity for every company in order to meet the increasing customer demands, to face the global competition and to make profit. Multiagent-based approach is appropriate for eSCM because it shows many of the characteristics a SCM system should have. For this reason, we have proposed a multiagent-based eSCM model which configures a virtual SC, automates the SC activities: selling, purchasing, manufacturing, planning, inventory, etc. This model will allow a better coordination of the supply chain network and will increase the effectiveness of Web and intel-ligent technologies employed in eSCM software.

  13. Efficient Model-Based Diagnosis Engine

    Science.gov (United States)

    Fijany, Amir; Vatan, Farrokh; Barrett, Anthony; James, Mark; Mackey, Ryan; Williams, Colin

    2009-01-01

    An efficient diagnosis engine - a combination of mathematical models and algorithms - has been developed for identifying faulty components in a possibly complex engineering system. This model-based diagnosis engine embodies a twofold approach to reducing, relative to prior model-based diagnosis engines, the amount of computation needed to perform a thorough, accurate diagnosis. The first part of the approach involves a reconstruction of the general diagnostic engine to reduce the complexity of the mathematical-model calculations and of the software needed to perform them. The second part of the approach involves algorithms for computing a minimal diagnosis (the term "minimal diagnosis" is defined below). A somewhat lengthy background discussion is prerequisite to a meaningful summary of the innovative aspects of the present efficient model-based diagnosis engine. In model-based diagnosis, the function of each component and the relationships among all the components of the engineering system to be diagnosed are represented as a logical system denoted the system description (SD). Hence, the expected normal behavior of the engineering system is the set of logical consequences of the SD. Faulty components lead to inconsistencies between the observed behaviors of the system and the SD (see figure). Diagnosis - the task of finding faulty components - is reduced to finding those components, the abnormalities of which could explain all the inconsistencies. The solution of the diagnosis problem should be a minimal diagnosis, which is a minimal set of faulty components. A minimal diagnosis stands in contradistinction to the trivial solution, in which all components are deemed to be faulty, and which, therefore, always explains all inconsistencies.

  14. Modeling acquaintance networks based on balance theory

    Directory of Open Access Journals (Sweden)

    Vukašinović Vida

    2014-09-01

    Full Text Available An acquaintance network is a social structure made up of a set of actors and the ties between them. These ties change dynamically as a consequence of incessant interactions between the actors. In this paper we introduce a social network model called the Interaction-Based (IB model that involves well-known sociological principles. The connections between the actors and the strength of the connections are influenced by the continuous positive and negative interactions between the actors and, vice versa, the future interactions are more likely to happen between the actors that are connected with stronger ties. The model is also inspired by the social behavior of animal species, particularly that of ants in their colony. A model evaluation showed that the IB model turned out to be sparse. The model has a small diameter and an average path length that grows in proportion to the logarithm of the number of vertices. The clustering coefficient is relatively high, and its value stabilizes in larger networks. The degree distributions are slightly right-skewed. In the mature phase of the IB model, i.e., when the number of edges does not change significantly, most of the network properties do not change significantly either. The IB model was found to be the best of all the compared models in simulating the e-mail URV (University Rovira i Virgili of Tarragona network because the properties of the IB model more closely matched those of the e-mail URV network than the other models

  15. Satellite-based terrestrial production efficiency modeling

    Directory of Open Access Journals (Sweden)

    Obersteiner Michael

    2009-09-01

    Full Text Available Abstract Production efficiency models (PEMs are based on the theory of light use efficiency (LUE which states that a relatively constant relationship exists between photosynthetic carbon uptake and radiation receipt at the canopy level. Challenges remain however in the application of the PEM methodology to global net primary productivity (NPP monitoring. The objectives of this review are as follows: 1 to describe the general functioning of six PEMs (CASA; GLO-PEM; TURC; C-Fix; MOD17; and BEAMS identified in the literature; 2 to review each model to determine potential improvements to the general PEM methodology; 3 to review the related literature on satellite-based gross primary productivity (GPP and NPP modeling for additional possibilities for improvement; and 4 based on this review, propose items for coordinated research. This review noted a number of possibilities for improvement to the general PEM architecture - ranging from LUE to meteorological and satellite-based inputs. Current PEMs tend to treat the globe similarly in terms of physiological and meteorological factors, often ignoring unique regional aspects. Each of the existing PEMs has developed unique methods to estimate NPP and the combination of the most successful of these could lead to improvements. It may be beneficial to develop regional PEMs that can be combined under a global framework. The results of this review suggest the creation of a hybrid PEM could bring about a significant enhancement to the PEM methodology and thus terrestrial carbon flux modeling. Key items topping the PEM research agenda identified in this review include the following: LUE should not be assumed constant, but should vary by plant functional type (PFT or photosynthetic pathway; evidence is mounting that PEMs should consider incorporating diffuse radiation; continue to pursue relationships between satellite-derived variables and LUE, GPP and autotrophic respiration (Ra; there is an urgent need for

  16. Sole Searching

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    China wants the European Union to kick its anti-dumping measures on footwear to the curb Among all the advanced countries and regions, the European Union (EU) is China's most stable and mature trading partner. Since China established diplomatic ties with the European Economic Community in 1975, especially after the EU published its first policy paper on China in 1995, Sino-EU relations have developed rapidly, from an all-round partnership to an all-round strategic one. In addition to working together on ...

  17. Multivariate statistical modelling based on generalized linear models

    CERN Document Server

    Fahrmeir, Ludwig

    1994-01-01

    This book is concerned with the use of generalized linear models for univariate and multivariate regression analysis. Its emphasis is to provide a detailed introductory survey of the subject based on the analysis of real data drawn from a variety of subjects including the biological sciences, economics, and the social sciences. Where possible, technical details and proofs are deferred to an appendix in order to provide an accessible account for non-experts. Topics covered include: models for multi-categorical responses, model checking, time series and longitudinal data, random effects models, and state-space models. Throughout, the authors have taken great pains to discuss the underlying theoretical ideas in ways that relate well to the data at hand. As a result, numerous researchers whose work relies on the use of these models will find this an invaluable account to have on their desks. "The basic aim of the authors is to bring together and review a large part of recent advances in statistical modelling of m...

  18. Application of AFLP markers for population genetic study on half-smooth tongue sole Cynoglossus semilaevis

    Institute of Scientific and Technical Information of China (English)

    LIU Yunguo; LI Junfeng; YE Naihao

    2011-01-01

    The genetic diversity of wild and hatchery populations of half-smooth tongue sole Cynoglossus semilaevis, based on observation of amplified fragment length polymorphism (AFLP) was described. Two hundred individuals from four wild populations, Laizhou (LZ), Weihai (WH), Qingdao (QD), Rizhao (RZ), and one hatchery population, Mingbo (MB), were screened using eight different AFLP primer combinations. A total of 384 loci were screened in the five studied populations. 48.4%, 51.3%,50.7%, 49.3% and 45.8% of these loci were polymorphic among the individuals tested in the LZ, WH,QD, RZ and MB populations, respectively. The number of polymorphic loci detected by single primer combinations ranged from 17 to 35. The average heterozygosity of the LZ, WH, QD, RZ and MB populations was 0.072, 0.093, 0.092, 0.090 and 0.063, respectively. The WH population showed the highest genetic diversity in terms of total number of AFLP bands, total number of polymorphic bands,average heterozygosity and percentage of low frequency (0-0.2) polymorphic loci among all the populations,while the LZ population was the lowest among the wild populations. Compared with the wild populations,the hatchery population showed a low genetic viability.

  19. Continuous operation of an ultra-low-power microcontroller using glucose as the sole energy source.

    Science.gov (United States)

    Lee, Inyoung; Sode, Takashi; Loew, Noya; Tsugawa, Wakako; Lowe, Christopher Robin; Sode, Koji

    2017-07-15

    An ultimate goal for those engaged in research to develop implantable medical devices is to develop mechatronic implantable artificial organs such as artificial pancreas. Such devices would comprise at least a sensor module, an actuator module, and a controller module. For the development of optimal mechatronic implantable artificial organs, these modules should be self-powered and autonomously operated. In this study, we aimed to develop a microcontroller using the BioCapacitor principle. A direct electron transfer type glucose dehydrogenase was immobilized onto mesoporous carbon, and then deposited on the surface of a miniaturized Au electrode (7mm(2)) to prepare a miniaturized enzyme anode. The enzyme fuel cell was connected with a 100 μF capacitor and a power boost converter as a charge pump. The voltage of the enzyme fuel cell was increased in a stepwise manner by the charge pump from 330mV to 3.1V, and the generated electricity was charged into a 100μF capacitor. The charge pump circuit was connected to an ultra-low-power microcontroller. Thus prepared BioCapacitor based circuit was able to operate an ultra-low-power microcontroller continuously, by running a program for 17h that turned on an LED every 60s. Our success in operating a microcontroller using glucose as the sole energy source indicated the probability of realizing implantable self-powered autonomously operated artificial organs, such as artificial pancreas. Copyright © 2016 Elsevier B.V. All rights reserved.

  20. Endolimax piscium sp. nov. (Amoebozoa), causative agent of systemic granulomatous disease of cultured sole, Solea senegalensis Kaup.

    Science.gov (United States)

    Constenla, M; Padrós, F; Palenzuela, O

    2014-03-01

    A new amoeba species pathogenic for Senegalese sole is described based on ultrastructural analysis and SSU rDNA phylogenetic inference. The parasite presents round to ovoid trophozoites (inference methods than with ML or Bayesian trees. The use of stringent alignment sampling masks also caused instability and reduced support for some branches, including the monophyly of Endolimax spp. in the most conservative data sets. The characterization of other Archamoebae parasitizing fish could help to clarify the status of E. piscium and to interpret the large genetic distance observed between Endolimax species.

  1. Mechanics model for actin-based motility.

    Science.gov (United States)

    Lin, Yuan

    2009-02-01

    We present here a mechanics model for the force generation by actin polymerization. The possible adhesions between the actin filaments and the load surface, as well as the nucleation and capping of filament tips, are included in this model on top of the well-known elastic Brownian ratchet formulation. A closed form solution is provided from which the force-velocity relationship, summarizing the mechanics of polymerization, can be drawn. Model predictions on the velocity of moving beads driven by actin polymerization are consistent with experiment observations. This model also seems capable of explaining the enhanced actin-based motility of Listeria monocytogenes and beads by the presence of Vasodilator-stimulated phosphoprotein, as observed in recent experiments.

  2. An immune based dynamic intrusion detection model

    Institute of Scientific and Technical Information of China (English)

    LI Tao

    2005-01-01

    With the dynamic description method for self and antigen, and the concept of dynamic immune tolerance for lymphocytes in network-security domain presented in this paper, a new immune based dynamic intrusion detection model (Idid) is proposed. In Idid, the dynamic models and the corresponding recursive equations of the lifecycle of mature lymphocytes, and the immune memory are built. Therefore, the problem of the dynamic description of self and nonself in computer immune systems is solved, and the defect of the low efficiency of mature lymphocyte generating in traditional computer immune systems is overcome. Simulations of this model are performed, and the comparison experiment results show that the proposed dynamic intrusion detection model has a better adaptability than the traditional methods.

  3. Electrochemistry-based Battery Modeling for Prognostics

    Science.gov (United States)

    Daigle, Matthew J.; Kulkarni, Chetan Shrikant

    2013-01-01

    Batteries are used in a wide variety of applications. In recent years, they have become popular as a source of power for electric vehicles such as cars, unmanned aerial vehicles, and commericial passenger aircraft. In such application domains, it becomes crucial to both monitor battery health and performance and to predict end of discharge (EOD) and end of useful life (EOL) events. To implement such technologies, it is crucial to understand how batteries work and to capture that knowledge in the form of models that can be used by monitoring, diagnosis, and prognosis algorithms. In this work, we develop electrochemistry-based models of lithium-ion batteries that capture the significant electrochemical processes, are computationally efficient, capture the effects of aging, and are of suitable accuracy for reliable EOD prediction in a variety of usage profiles. This paper reports on the progress of such a model, with results demonstrating the model validity and accurate EOD predictions.

  4. Model based monitoring of stormwater runoff quality

    DEFF Research Database (Denmark)

    Birch, Heidi; Vezzaro, Luca; Mikkelsen, Peter Steen

    2012-01-01

    the information obtained about MPs discharged from the monitored system. A dynamic stormwater quality model was calibrated using MP data collected by volume-proportional and passive sampling in a storm drainage system in the outskirts of Copenhagen (Denmark) and a 10-year rain series was used to find annual......) for calibration of the model resulted in the same predicted level but narrower model prediction bounds than calibrations based on volume-proportional samples, allowing a better exploitation of the resources allocated for stormwater quality management.......Monitoring of micropollutants (MP) in stormwater is essential to evaluate the impacts of stormwater on the receiving aquatic environment. The aim of this study was to investigate how different strategies for monitoring of stormwater quality (combination of model with field sampling) affect...

  5. Image-based modelling of organogenesis.

    Science.gov (United States)

    Iber, Dagmar; Karimaddini, Zahra; Ünal, Erkan

    2016-07-01

    One of the major challenges in biology concerns the integration of data across length and time scales into a consistent framework: how do macroscopic properties and functionalities arise from the molecular regulatory networks-and how can they change as a result of mutations? Morphogenesis provides an excellent model system to study how simple molecular networks robustly control complex processes on the macroscopic scale despite molecular noise, and how important functional variants can emerge from small genetic changes. Recent advancements in three-dimensional imaging technologies, computer algorithms and computer power now allow us to develop and analyse increasingly realistic models of biological control. Here, we present our pipeline for image-based modelling that includes the segmentation of images, the determination of displacement fields and the solution of systems of partial differential equations on the growing, embryonic domains. The development of suitable mathematical models, the data-based inference of parameter sets and the evaluation of competing models are still challenging, and current approaches are discussed.

  6. State-Based Behavior Modeling of the Integrated SLS-MPCV System

    Science.gov (United States)

    Bonanne, Kevin H.

    2012-01-01

    In NASA's effort to foster a human spaceflight capability beyond Earth's orbit, two space systems are being developed - the Space Launch System (SLS) and the Multi-Purpose Crew Vehicle (MPCV). As of this time, the interactions between the two systems during launch are not fully detailed. To remedy this situation, a Systems Engineering approach utilizing models was developed to investigate the behavior of the integrated SLS-MPCV stack during ascent and abort situations. Specifically, this innovative approach combines aspects of Model-Based Systems Engineering (MBSE) and state analysis to simultaneously model the physical, functional, and behavioral aspects of systems. This approach focuses solely on the interactions between the systems, leaving much of the internal workings of either system at a logical level (i.e., black box). By utilizing this newly defined approach, a behavior model for the integrated SLS-MPCV stack was developed, emphasizing only the subset of interactions between the systems that impact behavior. Finally, analysis is performed within the model to investigate requirements gaps and examine the execution times of key behaviors related to various ascent phases and abort scenarios. The work described in this paper is merely a portion of the outlined effort being undertaken for this project; only a segment of the SLS-MPCV system behavior will be described.

  7. Model-based Tomographic Reconstruction Literature Search

    Energy Technology Data Exchange (ETDEWEB)

    Chambers, D H; Lehman, S K

    2005-11-30

    In the process of preparing a proposal for internal research funding, a literature search was conducted on the subject of model-based tomographic reconstruction (MBTR). The purpose of the search was to ensure that the proposed research would not replicate any previous work. We found that the overwhelming majority of work on MBTR which used parameterized models of the object was theoretical in nature. Only three researchers had applied the technique to actual data. In this note, we summarize the findings of the literature search.

  8. Soft sensor modeling based on Gaussian processes

    Institute of Scientific and Technical Information of China (English)

    XIONG Zhi-hua; HUANG Guo-hong; SHAO Hui-he

    2005-01-01

    In order to meet the demand of online optimal running, a novel soft sensor modeling approach based on Gaussian processes was proposed. The approach is moderately simple to implement and use without loss of performance. It is trained by optimizing the hyperparameters using the scaled conjugate gradient algorithm with the squared exponential covariance function employed. Experimental simulations show that the soft sensor modeling approach has the advantage via a real-world example in a refinery. Meanwhile, the method opens new possibilities for application of kernel methods to potential fields.

  9. History-based trust negotiation model

    Institute of Scientific and Technical Information of China (English)

    ZHAO Yi-zhu; ZHAO Yan-hua; LU Hong-wei

    2009-01-01

    Trust negotiation (TN) is an approach to establish trust between strangers through iterative disclosure of digital credentials. Speeding up subsequent negotiations between the same negotiators is a problem worth of research. This paper introduces the concept of visiting card, and presents a history-based trust negotiation (HBTN) model. HBTN creates an account for a counterpart at the first negotiation and records valid credentials that the counterpart disclosed during each trust negotiation in his historical information base (HIB). For the following negotiation, no more credentials need to be disclosed for both parties. HBTN speeds up subsequent negotiations between the entities that interact with each other frequently without impairing the privacy preservation.

  10. Preservation Obscures Pelagic Deep-Sea Fish Diversity: Doubling the Number of Sole-Bearing Opisthoproctids and Resurrection of the Genus Monacoa (Opisthoproctidae, Argentiniformes).

    Science.gov (United States)

    Poulsen, Jan Yde; Sado, Tetsuya; Hahn, Christoph; Byrkjedal, Ingvar; Moku, Masatoshi; Miya, Masaki

    2016-01-01

    The family Opisthoproctidae (barreleyes) constitutes one of the most peculiar looking and unknown deep-sea fish groups in terms of taxonomy and specialized adaptations. All the species in the family are united by the possession of tubular eyes, with one distinct lineage exhibiting also drastic shortening of the body. Two new species of the mesopelagic opisthoproctid mirrorbelly genus Monacoa are described based on pigmentation patterns of the "sole"-a unique vertebrate structure used in the reflection and control of bioluminescence in most short-bodied forms. Different pigmentation patterns of the soles, previously noted as intraspecific variations based on preserved specimens, are here shown species-specific and likely used for communication in addition to counter-illumination of down-welling sunlight. The genus Monacoa is resurrected from Opisthoproctus based on extensive morphological synaphomorphies pertaining to the anal fin and snout. Doubling the species diversity within sole-bearing opisthoproctids, including recognition of two genera, is unambiguously supported by mitogenomic DNA sequence data. Regular fixation with formalin and alcohol preservation is shown problematic concerning the retention of species-specific pigmentation patterns. Examination or photos of fresh material before formalin fixation is shown paramount for correct species recognition of sole-bearing opisthoproctids-a relatively unknown issue concerning species diversity in the deep-sea pelagic realm.

  11. Model-Based Trace-Checking

    CERN Document Server

    Howard, Y; Gravell, A; Ferreira, C; Augusto, J C

    2011-01-01

    Trace analysis can be a useful way to discover problems in a program under test. Rather than writing a special purpose trace analysis tool, this paper proposes that traces can usefully be analysed by checking them against a formal model using a standard model-checker or else an animator for executable specifications. These techniques are illustrated using a Travel Agent case study implemented in J2EE. We added trace beans to this code that write trace information to a database. The traces are then extracted and converted into a form suitable for analysis by Spin, a popular model-checker, and Pro-B, a model-checker and animator for the B notation. This illustrates the technique, and also the fact that such a system can have a variety of models, in different notations, that capture different features. These experiments have demonstrated that model-based trace-checking is feasible. Future work is focussed on scaling up the approach to larger systems by increasing the level of automation.

  12. Individual eye model based on wavefront aberration

    Science.gov (United States)

    Guo, Huanqing; Wang, Zhaoqi; Zhao, Qiuling; Quan, Wei; Wang, Yan

    2005-03-01

    Based on the widely used Gullstrand-Le Grand eye model, the individual human eye model has been established here, which has individual corneal data, anterior chamber depth and the eyeball depth. Furthermore, the foremost thing is that the wavefront aberration calculated from the individual eye model is equal to the eye's wavefront aberration measured with the Hartmann-shack wavefront sensor. There are four main steps to build the model. Firstly, the corneal topography instrument was used to measure the corneal surfaces and depth. And in order to input cornea into the optical model, high-order aspheric surface-Zernike Fringe Sag surface was chosen to fit the corneal surfaces. Secondly, the Hartmann-shack wavefront sensor, which can offer the Zernike polynomials to describe the wavefront aberration, was built to measure the wavefront aberration of the eye. Thirdly, the eye's axial lengths among every part were measured with A-ultrasonic technology. Then the data were input into the optical design software-ZEMAX and the crystalline lens's shapes were optimized with the aberration as the merit function. The individual eye model, which has the same wavefront aberrations with the real eye, is established.

  13. Agent Based Model of Livestock Movements

    Science.gov (United States)

    Miron, D. J.; Emelyanova, I. V.; Donald, G. E.; Garner, G. M.

    The modelling of livestock movements within Australia is of national importance for the purposes of the management and control of exotic disease spread, infrastructure development and the economic forecasting of livestock markets. In this paper an agent based model for the forecasting of livestock movements is presented. This models livestock movements from farm to farm through a saleyard. The decision of farmers to sell or buy cattle is often complex and involves many factors such as climate forecast, commodity prices, the type of farm enterprise, the number of animals available and associated off-shore effects. In this model the farm agent's intelligence is implemented using a fuzzy decision tree that utilises two of these factors. These two factors are the livestock price fetched at the last sale and the number of stock on the farm. On each iteration of the model farms choose either to buy, sell or abstain from the market thus creating an artificial supply and demand. The buyers and sellers then congregate at the saleyard where livestock are auctioned using a second price sealed bid. The price time series output by the model exhibits properties similar to those found in real livestock markets.

  14. Agent-based modeling in ecological economics.

    Science.gov (United States)

    Heckbert, Scott; Baynes, Tim; Reeson, Andrew

    2010-01-01

    Interconnected social and environmental systems are the domain of ecological economics, and models can be used to explore feedbacks and adaptations inherent in these systems. Agent-based modeling (ABM) represents autonomous entities, each with dynamic behavior and heterogeneous characteristics. Agents interact with each other and their environment, resulting in emergent outcomes at the macroscale that can be used to quantitatively analyze complex systems. ABM is contributing to research questions in ecological economics in the areas of natural resource management and land-use change, urban systems modeling, market dynamics, changes in consumer attitudes, innovation, and diffusion of technology and management practices, commons dilemmas and self-governance, and psychological aspects to human decision making and behavior change. Frontiers for ABM research in ecological economics involve advancing the empirical calibration and validation of models through mixed methods, including surveys, interviews, participatory modeling, and, notably, experimental economics to test specific decision-making hypotheses. Linking ABM with other modeling techniques at the level of emergent properties will further advance efforts to understand dynamics of social-environmental systems.

  15. Habitat selection of juvenile sole (Solea solea L.): Consequences for shoreface nourishment

    Science.gov (United States)

    Post, Marjolein H. M.; Blom, Ewout; Chen, Chun; Bolle, Loes J.; Baptist, Martin J.

    2017-04-01

    The shallow coastal zone is an essential nursery habitat for juvenile flatfish species such as sole (Solea solea L.). The increased frequency of shoreface nourishments along the coast is likely to affect this nursery function by altering important habitat conditions, including sediment grain size. Sediment preference of juvenile sole (41-91 mm) was studied in a circular preference chamber in order to understand the relationship between grain size and sole distribution. The preference tests were carried out at 11 °C and 20 °C to reflect seasonal influences. The juveniles showed a significant preference for finer sediments. This preference was not length dependent (within the length range tested) nor affected by either temperatures. Juvenile sole have a small home range and are not expected to move in response to unfavourable conditions. As a result, habitat alterations may have consequences for juvenile survival and subsequently for recruitment to adult populations. It is therefore important to carefully consider nourishment grain size characteristics to safeguard suitable nursery habitats for juvenile sole.

  16. Efficacy of Tramadol as a Sole Analgesic for Postoperative Pain in Male and Female Mice

    Science.gov (United States)

    Wolfe, A Marissa; Kennedy, Lucy H; Na, Jane J; Nemzek-Hamlin, Jean A

    2015-01-01

    Tramadol is a centrally acting weak μ opioid agonist that has few of the adverse side effects common to other opioids. Little work has been done to establish an effective analgesic dose of tramadol specific for surgical laparotomy and visceral manipulation in mice. We used general appearance parameters to score positive indicators of pain including posture, coat condition, activity, breathing, and interactions with other mice, activity events (that is, the number of times each mouse stretched up in a 3-min period) used as an indicator of decreased pain, von Frey fibers, and plasma levels of corticosterone to determine whether tramadol at 20, 40, or 80 mg/kg prevented postoperative pain in male and female C57BL/6 mice. A ventral midline laparotomy with typhlectomy was used as a model of postoperative pain. In male mice, none of the markers differed between groups that received tramadol (regardless of dose) and the saline-treated controls. However, general appearance scores and plasma corticosterone levels were lower in female mice that received 80 mg/kg tramadol compared with saline. In summary, for severe postoperative pain after laparotomy and aseptic typhlectomy, tramadol was ineffective in male C57BL/6 mice at all doses tested. Although 80 mg/kg ameliorated postoperative pain in female C57BL/6 mice, this dose is very close to the threshold reported to cause toxic side effects, such as tremors and seizures. Therefore, we do not recommend the use of tramadol as a sole analgesic in this mouse model of postoperative pain. PMID:26224442

  17. Efficacy of Tramadol as a Sole Analgesic for Postoperative Pain in Male and Female Mice.

    Science.gov (United States)

    Wolfe, A Marissa; Kennedy, Lucy H; Na, Jane J; Nemzek-Hamlin, Jean A

    2015-07-01

    Tramadol is a centrally acting weak μ opioid agonist that has few of the adverse side effects common to other opioids. Little work has been done to establish an effective analgesic dose of tramadol specific for surgical laparotomy and visceral manipulation in mice. We used general appearance parameters to score positive indicators of pain including posture, coat condition, activity, breathing, and interactions with other mice, activity events (that is, the number of times each mouse stretched up in a 3-min period) used as an indicator of decreased pain, von Frey fibers, and plasma levels of corticosterone to determine whether tramadol at 20, 40, or 80 mg/kg prevented postoperative pain in male and female C57BL/6 mice. A ventral midline laparotomy with typhlectomy was used as a model of postoperative pain. In male mice, none of the markers differed between groups that received tramadol (regardless of dose) and the saline-treated controls. However, general appearance scores and plasma corticosterone levels were lower in female mice that received 80 mg/kg tramadol compared with saline. In summary, for severe postoperative pain after laparotomy and aseptic typhlectomy, tramadol was ineffective in male C57BL/6 mice at all doses tested. Although 80 mg/kg ameliorated postoperative pain in female C57BL/6 mice, this dose is very close to the threshold reported to cause toxic side effects, such as tremors and seizures. Therefore, we do not recommend the use of tramadol as a sole analgesic in this mouse model of postoperative pain.

  18. Model based risk assessment - the CORAS framework

    Energy Technology Data Exchange (ETDEWEB)

    Gran, Bjoern Axel; Fredriksen, Rune; Thunem, Atoosa P-J.

    2004-04-15

    Traditional risk analysis and assessment is based on failure-oriented models of the system. In contrast to this, model-based risk assessment (MBRA) utilizes success-oriented models describing all intended system aspects, including functional, operational and organizational aspects of the target. The target models are then used as input sources for complementary risk analysis and assessment techniques, as well as a basis for the documentation of the assessment results. The EU-funded CORAS project developed a tool-supported methodology for the application of MBRA in security-critical systems. The methodology has been tested with successful outcome through a series of seven trial within the telemedicine and ecommerce areas. The CORAS project in general and the CORAS application of MBRA in particular have contributed positively to the visibility of model-based risk assessment and thus to the disclosure of several potentials for further exploitation of various aspects within this important research field. In that connection, the CORAS methodology's possibilities for further improvement towards utilization in more complex architectures and also in other application domains such as the nuclear field can be addressed. The latter calls for adapting the framework to address nuclear standards such as IEC 60880 and IEC 61513. For this development we recommend applying a trial driven approach within the nuclear field. The tool supported approach for combining risk analysis and system development also fits well with the HRP proposal for developing an Integrated Design Environment (IDE) providing efficient methods and tools to support control room systems design. (Author)

  19. Verifying the functional ability of microstructured surfaces by model-based testing

    Science.gov (United States)

    Hartmann, Wito; Weckenmann, Albert

    2014-09-01

    Micro- and nanotechnology enables the use of new product features such as improved light absorption, self-cleaning or protection, which are based, on the one hand, on the size of functional nanostructures and the other hand, on material-specific properties. With the need to reliably measure progressively smaller geometric features, coordinate and surface-measuring instruments have been refined and now allow high-resolution topography and structure measurements down to the sub-nanometre range. Nevertheless, in many cases it is not possible to make a clear statement about the functional ability of the workpiece or its topography because conventional concepts of dimensioning and tolerancing are solely geometry oriented and standardized surface parameters are not sufficient to consider interaction with non-geometric parameters, which are dominant for functions such as sliding, wetting, sealing and optical reflection. To verify the functional ability of microstructured surfaces, a method was developed based on a parameterized mathematical-physical model of the function. From this model, function-related properties can be identified and geometric parameters can be derived, which may be different for the manufacturing and verification processes. With this method it is possible to optimize the definition of the shape of the workpiece regarding the intended function by applying theoretical and experimental knowledge, as well as modelling and simulation. Advantages of this approach will be discussed and demonstrated by the example of a microstructured inking roll.

  20. Business Models for NFC based mobile payments

    Directory of Open Access Journals (Sweden)

    Johannes Sang Un Chae

    2015-01-01

    Full Text Available Purpose: The purpose of the paper is to develop a business model framework for NFC based mobile payment solutions consisting of four mutually interdepended components: the value service, value network, value architecture, and value finance. Design: Using a comparative case study method, the paper investigates Google Wallet and ISIS Mobile Wallet and their underlying business models. Findings: Google Wallet and ISIS Mobile Wallet are focusing on providing an enhanced customer experience with their mobile wallet through a multifaceted value proposition. The delivery of its offering requires cooperation from multiple stakeholders and the creation of an ecosystem. Furthermore, they focus on the scalability of their value propositions. Originality / value: The paper offers an applicable business model framework that allows practitioners and academics to study current and future mobile payment approaches.

  1. Realistic face modeling based on multiple deformations

    Institute of Scientific and Technical Information of China (English)

    GONG Xun; WANG Guo-yin

    2007-01-01

    On the basis of the assumption that the human face belongs to a linear class, a multiple-deformation model is proposed to recover face shape from a few points on a single 2D image. Compared to the conventional methods, this study has the following advantages. First, the proposed modified 3D sparse deforming model is a noniterative approach that can compute global translation efficiently and accurately. Subsequently, the overfitting problem can be alleviated based on the proposed multiple deformation model. Finally, by keeping the main features, the texture generated is realistic. The comparison results show that this novel method outperforms the existing methods by using ground truth data and that realistic 3D faces can be recovered efficiently from a single photograph.

  2. Business Models for NFC Based Mobile Payments

    DEFF Research Database (Denmark)

    Chae, Johannes Sang-Un; Hedman, Jonas

    2015-01-01

    from multiple stakeholders and the creation of an ecosystem. Furthermore, they focus on the scalability of their value propositions. Originality / value: The paper offers an applicable business model framework that allows practitioners and academics to study current and future mobile payment approaches.......Purpose: The purpose of the paper is to develop a business model framework for NFC based mobile payment solutions consisting of four mutually interdepended components: the value service, value network, value architecture, and value finance. Design: Using a comparative case study method, the paper...... investigates Google Wallet and ISIS Mobile Wallet and their underlying business models. Findings: Google Wallet and ISIS Mobile Wallet are focusing on providing an enhanced customer experience with their mobile wallet through a multifaceted value proposition. The delivery of its offering requires cooperation...

  3. On Reading-Based Writing Instruction Model

    Institute of Scientific and Technical Information of China (English)

    李大艳; 王建安

    2012-01-01

    English writing is a complex integrative process of comprehensive skills. A host of students are still unable to write a coherent English paragraph after having learned English for many years at school. To help college students improve their writing competence is a great challenge facing the English teaching in China. Researches on writing teaching method abroad have experienced prosperity. In China, however, researches in this field are far behind. There is great need to search for more efficient writing instruction model so that it can serve well in Chinese context. Enlightened by Krashen's input hypothesis and Swain's output hypothesis, the writer put forward Reading-Based Writing Instruction Model. This paper aims to discuss the effectiveness of this model from the different perspectives.

  4. Néron models and base change

    CERN Document Server

    Halle, Lars Halvard

    2016-01-01

    Presenting the first systematic treatment of the behavior of Néron models under ramified base change, this book can be read as an introduction to various subtle invariants and constructions related to Néron models of semi-abelian varieties, motivated by concrete research problems and complemented with explicit examples. Néron models of abelian and semi-abelian varieties have become an indispensable tool in algebraic and arithmetic geometry since Néron introduced them in his seminal 1964 paper. Applications range from the theory of heights in Diophantine geometry to Hodge theory. We focus specifically on Néron component groups, Edixhoven’s filtration and the base change conductor of Chai and Yu, and we study these invariants using various techniques such as models of curves, sheaves on Grothendieck sites and non-archimedean uniformization. We then apply our results to the study of motivic zeta functions of abelian varieties. The final chapter contains a list of challenging open questions. This book is a...

  5. Entropy-based consistent model driven architecture

    Science.gov (United States)

    Niepostyn, Stanisław Jerzy

    2016-09-01

    A description of software architecture is a plan of the IT system construction, therefore any architecture gaps affect the overall success of an entire project. The definitions mostly describe software architecture as a set of views which are mutually unrelated, hence potentially inconsistent. Software architecture completeness is also often described in an ambiguous way. As a result most methods of IT systems building comprise many gaps and ambiguities, thus presenting obstacles for software building automation. In this article the consistency and completeness of software architecture are mathematically defined based on calculation of entropy of the architecture description. Following this approach, in this paper we also propose our method of automatic verification of consistency and completeness of the software architecture development method presented in our previous article as Consistent Model Driven Architecture (CMDA). The proposed FBS (Functionality-Behaviour-Structure) entropy-based metric applied in our CMDA approach enables IT architects to decide whether the modelling process is complete and consistent. With this metric, software architects could assess the readiness of undergoing modelling work for the start of IT system building. It even allows them to assess objectively whether the designed software architecture of the IT system could be implemented at all. The overall benefit of such an approach is that it facilitates the preparation of complete and consistent software architecture more effectively as well as it enables assessing and monitoring of the ongoing modelling development status. We demonstrate this with a few industry examples of IT system designs.

  6. Concept Tree Based Information Retrieval Model

    Directory of Open Access Journals (Sweden)

    Chunyan Yuan

    2014-05-01

    Full Text Available This paper proposes a novel concept-based query expansion technique named Markov concept tree model (MCTM, discovering term relationship through the concept tree deduced by term markov network. We address two important issues for query expansion: the selection and the weighting of expansion search terms. In contrast to earlier methods, queries are expanded by adding those terms that are most similar to the concept of the query, rather than selecting terms that are similar to a signal query terms. Utilizing Markov network which is constructed according to the co-occurrence information of the terms in collection, it generate concept tree for each original query term, remove the redundant and irrelevant nodes in concept tree, then adjust the weight of original query and the weight of expansion term based on a pruning algorithm. We use this model for query expansion and evaluate the effectiveness of the model by examining the accuracy and robustness of the expansion methods, Compared with the baseline model, the experiments on standard dataset reveal that this method can achieve a better query quality

  7. Inference-based procedural modeling of solids

    KAUST Repository

    Biggers, Keith

    2011-11-01

    As virtual environments become larger and more complex, there is an increasing need for more automated construction algorithms to support the development process. We present an approach for modeling solids by combining prior examples with a simple sketch. Our algorithm uses an inference-based approach to incrementally fit patches together in a consistent fashion to define the boundary of an object. This algorithm samples and extracts surface patches from input models, and develops a Petri net structure that describes the relationship between patches along an imposed parameterization. Then, given a new parameterized line or curve, we use the Petri net to logically fit patches together in a manner consistent with the input model. This allows us to easily construct objects of varying sizes and configurations using arbitrary articulation, repetition, and interchanging of parts. The result of our process is a solid model representation of the constructed object that can be integrated into a simulation-based environment. © 2011 Elsevier Ltd. All rights reserved.

  8. A Dynamic Web Page Prediction Model Based on Access Patterns to Offer Better User Latency

    CERN Document Server

    Mukhopadhyay, Debajyoti; Saha, Dwaipayan; Kim, Young-Chon

    2011-01-01

    The growth of the World Wide Web has emphasized the need for improvement in user latency. One of the techniques that are used for improving user latency is Caching and another is Web Prefetching. Approaches that bank solely on caching offer limited performance improvement because it is difficult for caching to handle the large number of increasingly diverse files. Studies have been conducted on prefetching models based on decision trees, Markov chains, and path analysis. However, the increased uses of dynamic pages, frequent changes in site structure and user access patterns have limited the efficacy of these static techniques. In this paper, we have proposed a methodology to cluster related pages into different categories based on the access patterns. Additionally we use page ranking to build up our prediction model at the initial stages when users haven't already started sending requests. This way we have tried to overcome the problems of maintaining huge databases which is needed in case of log based techn...

  9. Model-based vision for car following

    Science.gov (United States)

    Schneiderman, Henry; Nashman, Marilyn; Lumia, Ronald

    1993-08-01

    This paper describes a vision processing algorithm that supports autonomous car following. The algorithm visually tracks the position of a `lead vehicle' from the vantage of a pursuing `chase vehicle.' The algorithm requires a 2-D model of the back of the lead vehicle. This model is composed of line segments corresponding to features that give rise to strong edges. There are seven sequential stages of computation: (1) Extracting edge points; (2) Associating extracted edge points with the model features; (3) Determining the position of each model feature; (4) Determining the model position; (5) Updating the motion model of the object; (6) Predicting the position of the object in next image; (7) Predicting the location of all object features from prediction of object position. All processing is confined to the 2-D image plane. The 2-D model location computed in this processing is used to determine the position of the lead vehicle with respect to a 3-D coordinate frame affixed to the chase vehicle. This algorithm has been used as part of a complete system to drive an autonomous vehicle, a High Mobility Multipurpose Wheeled Vehicle (HMMWV) such that it follows a lead vehicle at speeds up to 35 km/hr. The algorithm runs at an update rate of 15 Hertz and has a worst case computational delay of 128 ms. The algorithm is implemented under the NASA/NBS Standard Reference Model for Telerobotic Control System Architecture (NASREM) and runs on a dedicated vision processing engine and a VME-based multiprocessor system.

  10. Model-based explanation of plant knowledge

    Energy Technology Data Exchange (ETDEWEB)

    Huuskonen, P.J. [VTT Electronics, Oulu (Finland). Embedded Software

    1997-12-31

    This thesis deals with computer explanation of knowledge related to design and operation of industrial plants. The needs for explanation are motivated through case studies and literature reviews. A general framework for analysing plant explanations is presented. Prototypes demonstrate key mechanisms for implementing parts of the framework. Power plants, steel mills, paper factories, and high energy physics control systems are studied to set requirements for explanation. The main problems are seen to be either lack or abundance of information. Design knowledge in particular is found missing at plants. Support systems and automation should be enhanced with ways to explain plant knowledge to the plant staff. A framework is formulated for analysing explanations of plant knowledge. It consists of three parts: 1. a typology of explanation, organised by the class of knowledge (factual, functional, or strategic) and by the target of explanation (processes, automation, or support systems), 2. an identification of explanation tasks generic for the plant domain, and 3. an identification of essential model types for explanation (structural, behavioural, functional, and teleological). The tasks use the models to create the explanations of the given classes. Key mechanisms are discussed to implement the generic explanation tasks. Knowledge representations based on objects and their relations form a vocabulary to model and present plant knowledge. A particular class of models, means-end models, are used to explain plant knowledge. Explanations are generated through searches in the models. Hypertext is adopted to communicate explanations over dialogue based on context. The results are demonstrated in prototypes. The VICE prototype explains the reasoning of an expert system for diagnosis of rotating machines at power plants. The Justifier prototype explains design knowledge obtained from an object-oriented plant design tool. Enhanced access mechanisms into on-line documentation are

  11. [Mechanical stimulation of soles' support zones: non-invasive method of activation of generators of stepping movements in man].

    Science.gov (United States)

    Tomilovskaia, E S; Moshonkina, T R; Gorodnichev, R M; Shigueva, T A; Zakirova, A Z; Pivovarova, E A; Savokhin, A A; Selionov, V A; Semenov, Iu S; Brevnov, V V; Kitov, V V; Gerasimenko, Iu P; Kozlovskaia, I B

    2013-01-01

    The effects of mechanical stimulation of the soles' support zones in regimens of slow and fastwalking (75 and 120 steps per minute) were studied using the model of supportlessness (legs suspension). 20 healthy subjects participated in the study. EMG activity of hip and shin muscles was recorded. Kinematic of leg movements was assessed with the use of videoanalysis system. Support stimulation was followed by leg movements in 80% of cases, in 53% it was a locomotion-like movement. EMG bursts accompanied the movements. Involvement order and alteration of bursts in muscles were similar to voluntary walking. EMG activity occurred with a delay of 5.17 ± 1.08 seconds for hip muscles and 14.01 ± 2.82 seconds for shin muscles, frequency of bursts differed from stimulation frequency. Support stimulation was followed by leg movements in 80% of cases, in 53% of which they had characteristics of locomotions being accompanied by the burst-like electromyographic activities. Involvement order of the leg muscles and organization of antagonistic muscles activities were analogous to that of voluntary walking. The latencies of electromyographic activity in hip muscles composed 5.17 ± 1.083 s and 14.01 ± 2.82 s - for shin muscles, frequency of bursts differed significantly from stimulation frequency. In 31% of cases the electromyographical activity following the stimulation of the soles' support zones was not burst-like. Its amplitude rose smoothly reaching a certain level that was subsequently maintained. Results of the study showed that soles' support zones stimulation in regimen of locomotion can activate a locomotor generator and that effect evoked by this stimulation includes not only rhythmical but also non-rhythmical (probably postural) components of walking.

  12. Eye development and retinal differentiation in an altricial fish species, the senegalese sole (Solea senegalensis, Kaup 1858).

    Science.gov (United States)

    Bejarano-Escobar, Ruth; Blasco, Manuel; DeGrip, Willem J; Oyola-Velasco, José Antonio; Martín-Partido, Gervasio; Francisco-Morcillo, Javier

    2010-11-15

    We describe the major events in the retinogenesis in an altricial fish species, the Senegalese sole. The major developmental events in the sole retina occurred early after hatching (posthatching day 0, P0). Thus, (1) plexiform layers became recognizable at P1. (2) Proliferative activity disappeared from the central retina at P1, and, as development progressed, became restricted to cells located in the circumferential germinal zone, and to sparse cells dispersed throughout the inner nuclear layer and the outer nuclear layer. (3) Apoptotic cells were sparsely observed, randomly localized in all three nuclear layers of the early posthatching retina from P0 to P4. (4) The first synaptic vesicles were detected at P0 in early postmitotic ganglion cells. However, their appearance in the plexiform layers was delayed until P2. (5) The neurochemical development of most major retinal cell classes occurred between P0 and P5. Thus, although Isl1 immunoreactive ganglion cells were the first to become postmitotic in the vitreal surface of the central retina at P0, the first glutamine synthetase-expressing Müller cells appeared in the central retina by P5. The onset of expression for other retinal markers, such as rod opsin, calretinin, parvalbumin, a-tyrosine hydroxylase, and a-protein kinase C, occurred between P2 and P4. Our results suggest that the most relevant processes involved in Senegalese sole retinogenesis occur during the prolarval and early larval stages (P0–P5). Furthermore, we conclude that altricial fish species may constitute a convenient model organism to address the relationship between the structural and functional development of sensory organs with the acquisition of behavioral repertoires.

  13. Family-Based Model Checking Without a Family-Based Model Checker

    DEFF Research Database (Denmark)

    Dimovski, Aleksandar; Al-Sibahi, Ahmad Salim; Brabrand, Claus;

    2015-01-01

    be used to model-check variational models using the standard version of (single system) SPIN. The abstractions are first defined as Galois connections on semantic domains. We then show how to translate them into syntactic source-to-source transformations on variational models. This allows the use of SPIN...... with all its accumulated optimizations for efficient verification of variational models without any knowledge about variability. We demonstrate the practicality of this method on several examples using both the SNIP (family based) and SPIN (single system) model checkers....

  14. Child adjustment in joint-custody versus sole-custody arrangements: a meta-analytic review.

    Science.gov (United States)

    Bauserman, Robert

    2002-03-01

    The author meta-analyzed studies comparing child adjustment in joint physical or joint legal custody with sole-custody settings, including comparisons with paternal custody and intact families where possible. Children in joint physical or legal custody were better adjusted than children in sole-custody settings, but no different from those in intact families. More positive adjustment of joint-custody children held for separate comparisons of general adjustment, family relationships, self-esteem, emotional and behavioral adjustment, and divorce-specific adjustment. Joint-custody parents reported less current and past conflict than did sole-custody parents, but this did not explain the better adjustment of joint-custody children. The results are consistent with the hypothesis that joint custody can be advantageous for children in some cases, possibly by facilitating ongoing positive involvement with both parents.

  15. All-pairs Shortest Path Algorithm based on MPI+CUDA Distributed Parallel Programming Model

    Directory of Open Access Journals (Sweden)

    Qingshuang Wu

    2013-12-01

    Full Text Available In view of the problem that computing shortest paths in a graph is a complex and time-consuming process, and the traditional algorithm that rely on the CPU as computing unit solely can't meet the demand of real-time processing, in this paper, we present an all-pairs shortest paths algorithm using MPI+CUDA hybrid programming model, which can take use of the overwhelming computing power of the GPU cluster to speed up the processing. This proposed algorithm can combine the advantages of MPI and CUDA programming model, and can realize two-level parallel computing. In the cluster-level, we take use of the MPI programming model to achieve a coarse-grained parallel computing between the computational nodes of the GPU cluster. In the node-level, we take use of the CUDA programming model to achieve a GPU-accelerated fine grit parallel computing in each computational node internal. The experimental results show that the MPI+CUDA-based parallel algorithm can take full advantage of the powerful computing capability of the GPU cluster, and can achieve about hundreds of time speedup; The whole algorithm has good computing performance, reliability and scalability, and it is able to meet the demand of real-time processing of massive spatial shortest path analysis

  16. Model-based cap thickness and peak cap stress prediction for carotid MRI.

    Science.gov (United States)

    Kok, Annette M; van der Lugt, Aad; Verhagen, Hence J M; van der Steen, Antonius F W; Wentzel, Jolanda J; Gijsen, Frank J H

    2017-07-26

    A rupture-prone carotid plaque can potentially be identified by calculating the peak cap stress (PCS). For these calculations, plaque geometry from MRI is often used. Unfortunately, MRI is hampered by a low resolution, leading to an overestimation of cap thickness and an underestimation of PCS. We developed a model to reconstruct the cap based on plaque geometry to better predict cap thickness and PCS. We used histological stained plaques from 34 patients. These plaques were segmented and served as the ground truth. Sections of these plaques contained 93 necrotic cores with a cap thickness Caps below the MRI resolution (n=31) were (digitally removed and) reconstructed according to the geometry-based model. Cap thickness and PCS were determined for the ground truth, readers, and reconstructed geometries. Cap thickness was 0.07mm for the ground truth, 0.23mm for the readers, and 0.12mm for the reconstructed geometries. The model predicts cap thickness significantly better than the readers. PCS was 464kPa for the ground truth, 262kPa for the readers and 384kPa for the reconstructed geometries. The model did not predict the PCS significantly better than the readers. The geometry-based model provided a significant improvement for cap thickness estimation and can potentially help in rupture-risk prediction, solely based on cap thickness. Estimation of PCS estimation did not improve, probably due to the complex shape of the plaques. Copyright © 2017 The Author(s). Published by Elsevier Ltd.. All rights reserved.

  17. Grid based calibration of SWAT hydrological models

    Directory of Open Access Journals (Sweden)

    D. Gorgan

    2012-07-01

    Full Text Available The calibration and execution of large hydrological models, such as SWAT (soil and water assessment tool, developed for large areas, high resolution, and huge input data, need not only quite a long execution time but also high computation resources. SWAT hydrological model supports studies and predictions of the impact of land management practices on water, sediment, and agricultural chemical yields in complex watersheds. The paper presents the gSWAT application as a web practical solution for environmental specialists to calibrate extensive hydrological models and to run scenarios, by hiding the complex control of processes and heterogeneous resources across the grid based high computation infrastructure. The paper highlights the basic functionalities of the gSWAT platform, and the features of the graphical user interface. The presentation is concerned with the development of working sessions, interactive control of calibration, direct and basic editing of parameters, process monitoring, and graphical and interactive visualization of the results. The experiments performed on different SWAT models and the obtained results argue the benefits brought by the grid parallel and distributed environment as a solution for the processing platform. All the instances of SWAT models used in the reported experiments have been developed through the enviroGRIDS project, targeting the Black Sea catchment area.

  18. Physics-based models of the plasmasphere

    Energy Technology Data Exchange (ETDEWEB)

    Jordanova, Vania K [Los Alamos National Laboratory; Pierrard, Vivane [BELGIUM; Goldstein, Jerry [SWRI; Andr' e, Nicolas [ESTEC/ESA; Kotova, Galina A [SRI, RUSSIA; Lemaire, Joseph F [BELGIUM; Liemohn, Mike W [U OF MICHIGAN; Matsui, H [UNIV OF NEW HAMPSHIRE

    2008-01-01

    We describe recent progress in physics-based models of the plasmasphere using the Auid and the kinetic approaches. Global modeling of the dynamics and inAuence of the plasmasphere is presented. Results from global plasmasphere simulations are used to understand and quantify (i) the electric potential pattern and evolution during geomagnetic storms, and (ii) the inAuence of the plasmasphere on the excitation of electromagnetic ion cyclotron (ElvIIC) waves a.nd precipitation of energetic ions in the inner magnetosphere. The interactions of the plasmasphere with the ionosphere a.nd the other regions of the magnetosphere are pointed out. We show the results of simulations for the formation of the plasmapause and discuss the inAuence of plasmaspheric wind and of ultra low frequency (ULF) waves for transport of plasmaspheric material. Theoretical formulations used to model the electric field and plasma distribution in the plasmasphere are given. Model predictions are compared to recent CLUSTER and MAGE observations, but also to results of earlier models and satellite observations.

  19. Microtechnology-Based Multi-Organ Models

    Directory of Open Access Journals (Sweden)

    Seung Hwan Lee

    2017-05-01

    Full Text Available Drugs affect the human body through absorption, distribution, metabolism, and elimination (ADME processes. Due to their importance, the ADME processes need to be studied to determine the efficacy and side effects of drugs. Various in vitro model systems have been developed and used to realize the ADME processes. However, conventional model systems have failed to simulate the ADME processes because they are different from in vivo, which has resulted in a high attrition rate of drugs and a decrease in the productivity of new drug development. Recently, a microtechnology-based in vitro system called “organ-on-a-chip” has been gaining attention, with more realistic cell behavior and physiological reactions, capable of better simulating the in vivo environment. Furthermore, multi-organ-on-a-chip models that can provide information on the interaction between the organs have been developed. The ultimate goal is the development of a “body-on-a-chip”, which can act as a whole body model. In this review, we introduce and summarize the current progress in the development of multi-organ models as a foundation for the development of body-on-a-chip.

  20. Microtechnology-Based Multi-Organ Models.

    Science.gov (United States)

    Lee, Seung Hwan; Sung, Jong Hwan

    2017-05-21

    Drugs affect the human body through absorption, distribution, metabolism, and elimination (ADME) processes. Due to their importance, the ADME processes need to be studied to determine the efficacy and side effects of drugs. Various in vitro model systems have been developed and used to realize the ADME processes. However, conventional model systems have failed to simulate the ADME processes because they are different from in vivo, which has resulted in a high attrition rate of drugs and a decrease in the productivity of new drug development. Recently, a microtechnology-based in vitro system called "organ-on-a-chip" has been gaining attention, with more realistic cell behavior and physiological reactions, capable of better simulating the in vivo environment. Furthermore, multi-organ-on-a-chip models that can provide information on the interaction between the organs have been developed. The ultimate goal is the development of a "body-on-a-chip", which can act as a whole body model. In this review, we introduce and summarize the current progress in the development of multi-organ models as a foundation for the development of body-on-a-chip.

  1. Fault diagnosis based on continuous simulation models

    Science.gov (United States)

    Feyock, Stefan

    1987-01-01

    The results are described of an investigation of techniques for using continuous simulation models as basis for reasoning about physical systems, with emphasis on the diagnosis of system faults. It is assumed that a continuous simulation model of the properly operating system is available. Malfunctions are diagnosed by posing the question: how can we make the model behave like that. The adjustments that must be made to the model to produce the observed behavior usually provide definitive clues to the nature of the malfunction. A novel application of Dijkstra's weakest precondition predicate transformer is used to derive the preconditions for producing the required model behavior. To minimize the size of the search space, an envisionment generator based on interval mathematics was developed. In addition to its intended application, the ability to generate qualitative state spaces automatically from quantitative simulations proved to be a fruitful avenue of investigation in its own right. Implementations of the Dijkstra transform and the envisionment generator are reproduced in the Appendix.

  2. Flow based vs. demand based energy-water modelling

    Science.gov (United States)

    Rozos, Evangelos; Nikolopoulos, Dionysis; Efstratiadis, Andreas; Koukouvinos, Antonios; Makropoulos, Christos

    2015-04-01

    The water flow in hydro-power generation systems is often used downstream to cover other type of demands like irrigation and water supply. However, the typical case is that the energy demand (operation of hydro-power plant) and the water demand do not coincide. Furthermore, the water inflow into a reservoir is a stochastic process. Things become more complicated if renewable resources (wind-turbines or photovoltaic panels) are included into the system. For this reason, the assessment and optimization of the operation of hydro-power systems are challenging tasks that require computer modelling. This modelling should not only simulate the water budget of the reservoirs and the energy production/consumption (pumped-storage), but should also take into account the constraints imposed by the natural or artificial water network using a flow routing algorithm. HYDRONOMEAS, for example, uses an elegant mathematical approach (digraph) to calculate the flow in a water network based on: the demands (input timeseries), the water availability (simulated) and the capacity of the transmission components (properties of channels, rivers, pipes, etc.). The input timeseries of demand should be estimated by another model and linked to the corresponding network nodes. A model that could be used to estimate these timeseries is UWOT. UWOT is a bottom up urban water cycle model that simulates the generation, aggregation and routing of water demand signals. In this study, we explore the potentials of UWOT in simulating the operation of complex hydrosystems that include energy generation. The evident advantage of this approach is the use of a single model instead of one for estimation of demands and another for the system simulation. An application of UWOT in a large scale system is attempted in mainland Greece in an area extending over 130×170 km². The challenges, the peculiarities and the advantages of this approach are examined and critically discussed.

  3. Model-based Prognostics with Concurrent Damage Progression Processes

    Data.gov (United States)

    National Aeronautics and Space Administration — Model-based prognostics approaches rely on physics-based models that describe the behavior of systems and their components. These models must account for the several...

  4. The estimation of future surface water bodies at Olkiluoto area based on statistical terrain and land uplift models

    Energy Technology Data Exchange (ETDEWEB)

    Pohjola, J.; Turunen, J.; Lipping, T. [Tampere Univ. of Technology (Finland); Ikonen, A.

    2014-03-15

    In this working report the modelling effort of future landscape development and surface water body formation at the modelling area in the vicinity of the Olkiluoto Island is presented. Estimation of the features of future surface water bodies is based on probabilistic terrain and land uplift models presented in previous working reports. The estimation is done using a GIS-based toolbox called UNTAMO. The future surface water bodies are estimated in 10 000 years' time span with 1000 years' intervals for the safety assessment of disposal of spent nuclear fuel at the Olkiluoto site. In the report a brief overview on the techniques used for probabilistic terrain modelling, land uplift modelling and hydrological modelling are presented first. The latter part of the report describes the results of the modelling effort. The main features of the future landscape - the four lakes forming in the vicinity of the Olkiluoto Island - are identified and the probabilistic model of the shoreline displacement is presented. The area and volume of the four lakes is modelled in a probabilistic manner. All the simulations have been performed for three scenarios two of which are based on 10 realizations of the probabilistic digital terrain model (DTM) and 10 realizations of the probabilistic land uplift model. These two scenarios differ from each other by the eustatic curve used in the land uplift model. The third scenario employs 50 realizations of the probabilistic DTM while a deterministic land uplift model, derived solely from the current land uplift rate, is used. The results indicate that the two scenarios based on the probabilistic land uplift model behave in a similar manner while the third model overestimates past and future land uplift rates. The main features of the landscape are nevertheless similar also for the third scenario. Prediction results for the volumes of the future lakes indicate that a couple of highly probably lake formation scenarios can be identified

  5. A Comparison of Filter-based Approaches for Model-based Prognostics

    Data.gov (United States)

    National Aeronautics and Space Administration — Model-based prognostics approaches use domain knowledge about a system and its failure modes through the use of physics-based models. Model-based prognosis is...

  6. Structure-function relationship of a plant NCS1 member--homology modeling and mutagenesis identified residues critical for substrate specificity of PLUTO, a nucleobase transporter from Arabidopsis

    National Research Council Canada - National Science Library

    Witz, Sandra; Panwar, Pankaj; Schober, Markus; Deppe, Johannes; Pasha, Farhan Ahmad; Lemieux, M Joanne; Möhlmann, Torsten

    2014-01-01

    .... We present the first homology model of PLUTO, the sole plant NCS1 member from Arabidopsis based on the crystal structure of the benzyl hydantoin transporter MHP1 from Microbacterium liquefaciens...

  7. Cosmic emergy based ecological systems modelling

    Science.gov (United States)

    Chen, H.; Chen, G. Q.; Ji, X.

    2010-09-01

    Ecological systems modelling based on the unified biophysical measure of cosmic emergy in terms of embodied cosmic exergy is illustrated in this paper with ecological accounting, simulation and scenario analysis, by a case study for the regional socio-economic ecosystem associated with the municipality of Beijing. An urbanized regional ecosystem model with eight subsystems of natural support, agriculture, urban production, population, finance, land area, potential environmental impact, and culture is representatively presented in exergy circuit language with 12 state variables governing by corresponding ecodynamic equations, and 60 flows and auxiliary variables. To characterize the regional socio-economy as an ecosystem, a series of ecological indicators based on cosmic emergy are devised. For a systematic ecological account, cosmic exergy transformities are provided for various dimensions including climate flows, natural resources, industrial products, cultural products, population with educational hierarchy, and environmental emissions. For the urban ecosystem of Beijing in the period from 1990 to 2005, ecological accounting is carried out and characterized in full details. Taking 2000 as the starting point, systems modelling is realized to predict the urban evolution in a one hundred time horizon. For systems regulation, scenario analyses with essential policy-making implications are made to illustrate the long term systems effects of the expected water diversion and rise in energy price.

  8. Physiologically Based Pharmacokinetic (PBPK) Modeling of ...

    Science.gov (United States)

    Background: Quantitative estimation of toxicokinetic variability in the human population is a persistent challenge in risk assessment of environmental chemicals. Traditionally, inter-individual differences in the population are accounted for by default assumptions or, in rare cases, are based on human toxicokinetic data.Objectives: To evaluate the utility of genetically diverse mouse strains for estimating toxicokinetic population variability for risk assessment, using trichloroethylene (TCE) metabolism as a case study. Methods: We used data on oxidative and glutathione conjugation metabolism of TCE in 16 inbred and one hybrid mouse strains to calibrate and extend existing physiologically-based pharmacokinetic (PBPK) models. We added one-compartment models for glutathione metabolites and a two-compartment model for dichloroacetic acid (DCA). A Bayesian population analysis of inter-strain variability was used to quantify variability in TCE metabolism. Results: Concentration-time profiles for TCE metabolism to oxidative and glutathione conjugation metabolites varied across strains. Median predictions for the metabolic flux through oxidation was less variable (5-fold range) than that through glutathione conjugation (10-fold range). For oxidative metabolites, median predictions of trichloroacetic acid production was less variable (2-fold range) than DCA production (5-fold range), although uncertainty bounds for DCA exceeded the predicted variability. Conclusions:

  9. Model-based phase-shifting interferometer

    Science.gov (United States)

    Liu, Dong; Zhang, Lei; Shi, Tu; Yang, Yongying; Chong, Shiyao; Miao, Liang; Huang, Wei; Shen, Yibing; Bai, Jian

    2015-10-01

    A model-based phase-shifting interferometer (MPI) is developed, in which a novel calculation technique is proposed instead of the traditional complicated system structure, to achieve versatile, high precision and quantitative surface tests. In the MPI, the partial null lens (PNL) is employed to implement the non-null test. With some alternative PNLs, similar as the transmission spheres in ZYGO interferometers, the MPI provides a flexible test for general spherical and aspherical surfaces. Based on modern computer modeling technique, a reverse iterative optimizing construction (ROR) method is employed for the retrace error correction of non-null test, as well as figure error reconstruction. A self-compiled ray-tracing program is set up for the accurate system modeling and reverse ray tracing. The surface figure error then can be easily extracted from the wavefront data in forms of Zernike polynomials by the ROR method. Experiments of the spherical and aspherical tests are presented to validate the flexibility and accuracy. The test results are compared with those of Zygo interferometer (null tests), which demonstrates the high accuracy of the MPI. With such accuracy and flexibility, the MPI would possess large potential in modern optical shop testing.

  10. Rainwater harvesting: model-based design evaluation.

    Science.gov (United States)

    Ward, S; Memon, F A; Butler, D

    2010-01-01

    The rate of uptake of rainwater harvesting (RWH) in the UK has been slow to date, but is expected to gain momentum in the near future. The designs of two different new-build rainwater harvesting systems, based on simple methods, are evaluated using three different design methods, including a continuous simulation modelling approach. The RWH systems are shown to fulfill 36% and 46% of WC demand. Financial analyses reveal that RWH systems within large commercial buildings maybe more financially viable than smaller domestic systems. It is identified that design methods based on simple approaches generate tank sizes substantially larger than the continuous simulation. Comparison of the actual tank sizes and those calculated using continuous simulation established that the tanks installed are oversized for their associated demand level and catchment size. Oversizing tanks can lead to excessive system capital costs, which currently hinders the uptake of systems. Furthermore, it is demonstrated that the catchment area size is often overlooked when designing UK-based RWH systems. With respect to these findings, a recommendation for a transition from the use of simple tools to continuous simulation models is made.

  11. Depth filters containing diatomite achieve more efficient particle retention than filters solely containing cellulose fibers

    Directory of Open Access Journals (Sweden)

    Johannes Felix Buyel

    2015-12-01

    Full Text Available The clarification of biological feed stocks during the production of biopharmaceutical proteins is challenging when large quantities of particles must be removed, e.g. when processing crude plant extracts. Single-use depth filters are often preferred for clarification because they are simple to integrate and have a good safety profile. However, the combination of filter layers must be optimized in terms of nominal retention ratings to account for the unique particle size distribution in each feed stock. We have recently shown that predictive models can facilitate filter screening and the selection of appropriate filter layers. Here we expand our previous study by testing several filters with different retention ratings. The filters typically contain diatomite to facilitate the removal of fine particles. However, diatomite can interfere with the recovery of large biopharmaceutical molecules such as virus-like particles and aggregated proteins. Therefore, we also tested filtration devices composed solely of cellulose fibers and cohesive resin. The capacities of both filter types varied from 10 to 50 L m-2 when challenged with tobacco leaf extracts, but the filtrate turbidity was ~500-fold lower (~3.5 NTU when diatomite filters were used. We also tested pre coat filtration with dispersed diatomite, which achieved capacities of up to 120 L m-2 with turbidities of ~100 NTU using bulk plant extracts, and in contrast to the other depth filters did not require an upstream bag filter. Single pre-coat filtration devices can thus replace combinations of bag and depth filters to simplify the processing of plant extracts, potentially saving on time, labor and consumables. The protein concentrations of TSP, DsRed and antibody 2G12 were not affected by pre-coat filtration, indicating its general applicability during the manufacture of plant-derived biopharmaceutical proteins.

  12. Depth Filters Containing Diatomite Achieve More Efficient Particle Retention than Filters Solely Containing Cellulose Fibers.

    Science.gov (United States)

    Buyel, Johannes F; Gruchow, Hannah M; Fischer, Rainer

    2015-01-01

    The clarification of biological feed stocks during the production of biopharmaceutical proteins is challenging when large quantities of particles must be removed, e.g., when processing crude plant extracts. Single-use depth filters are often preferred for clarification because they are simple to integrate and have a good safety profile. However, the combination of filter layers must be optimized in terms of nominal retention ratings to account for the unique particle size distribution in each feed stock. We have recently shown that predictive models can facilitate filter screening and the selection of appropriate filter layers. Here we expand our previous study by testing several filters with different retention ratings. The filters typically contain diatomite to facilitate the removal of fine particles. However, diatomite can interfere with the recovery of large biopharmaceutical molecules such as virus-like particles and aggregated proteins. Therefore, we also tested filtration devices composed solely of cellulose fibers and cohesive resin. The capacities of both filter types varied from 10 to 50 L m(-2) when challenged with tobacco leaf extracts, but the filtrate turbidity was ~500-fold lower (~3.5 NTU) when diatomite filters were used. We also tested pre-coat filtration with dispersed diatomite, which achieved capacities of up to 120 L m(-2) with turbidities of ~100 NTU using bulk plant extracts, and in contrast to the other depth filters did not require an upstream bag filter. Single pre-coat filtration devices can thus replace combinations of bag and depth filters to simplify the processing of plant extracts, potentially saving on time, labor and consumables. The protein concentrations of TSP, DsRed and antibody 2G12 were not affected by pre-coat filtration, indicating its general applicability during the manufacture of plant-derived biopharmaceutical proteins.

  13. Human physiologically based pharmacokinetic model for propofol

    Directory of Open Access Journals (Sweden)

    Schnider Thomas W

    2005-04-01

    Full Text Available Abstract Background Propofol is widely used for both short-term anesthesia and long-term sedation. It has unusual pharmacokinetics because of its high lipid solubility. The standard approach to describing the pharmacokinetics is by a multi-compartmental model. This paper presents the first detailed human physiologically based pharmacokinetic (PBPK model for propofol. Methods PKQuest, a freely distributed software routine http://www.pkquest.com, was used for all the calculations. The "standard human" PBPK parameters developed in previous applications is used. It is assumed that the blood and tissue binding is determined by simple partition into the tissue lipid, which is characterized by two previously determined set of parameters: 1 the value of the propofol oil/water partition coefficient; 2 the lipid fraction in the blood and tissues. The model was fit to the individual experimental data of Schnider et. al., Anesthesiology, 1998; 88:1170 in which an initial bolus dose was followed 60 minutes later by a one hour constant infusion. Results The PBPK model provides a good description of the experimental data over a large range of input dosage, subject age and fat fraction. Only one adjustable parameter (the liver clearance is required to describe the constant infusion phase for each individual subject. In order to fit the bolus injection phase, for 10 or the 24 subjects it was necessary to assume that a fraction of the bolus dose was sequestered and then slowly released from the lungs (characterized by two additional parameters. The average weighted residual error (WRE of the PBPK model fit to the both the bolus and infusion phases was 15%; similar to the WRE for just the constant infusion phase obtained by Schnider et. al. using a 6-parameter NONMEM compartmental model. Conclusion A PBPK model using standard human parameters and a simple description of tissue binding provides a good description of human propofol kinetics. The major advantage of a

  14. CNEM: Cluster Based Network Evolution Model

    Directory of Open Access Journals (Sweden)

    Sarwat Nizamani

    2015-01-01

    Full Text Available This paper presents a network evolution model, which is based on the clustering approach. The proposed approach depicts the network evolution, which demonstrates the network formation from individual nodes to fully evolved network. An agglomerative hierarchical clustering method is applied for the evolution of network. In the paper, we present three case studies which show the evolution of the networks from the scratch. These case studies include: terrorist network of 9/11 incidents, terrorist network of WMD (Weapons Mass Destruction plot against France and a network of tweets discussing a topic. The network of 9/11 is also used for evaluation, using other social network analysis methods which show that the clusters created using the proposed model of network evolution are of good quality, thus the proposed method can be used by law enforcement agencies in order to further investigate the criminal networks

  15. Agent based modeling in tactical wargaming

    Science.gov (United States)

    James, Alex; Hanratty, Timothy P.; Tuttle, Daniel C.; Coles, John B.

    2016-05-01

    Army staffs at division, brigade, and battalion levels often plan for contingency operations. As such, analysts consider the impact and potential consequences of actions taken. The Army Military Decision-Making Process (MDMP) dictates identification and evaluation of possible enemy courses of action; however, non-state actors often do not exhibit the same level and consistency of planned actions that the MDMP was originally designed to anticipate. The fourth MDMP step is a particular challenge, wargaming courses of action within the context of complex social-cultural behaviors. Agent-based Modeling (ABM) and its resulting emergent behavior is a potential solution to model terrain in terms of the human domain and improve the results and rigor of the traditional wargaming process.

  16. Trip Generation Model Based on Destination Attractiveness

    Institute of Scientific and Technical Information of China (English)

    YAO Liya; GUAN Hongzhi; YAN Hai

    2008-01-01

    Traditional trip generation forecasting methods use unified average trip generation rates to determine trip generation volumes in various traffic zones without considering the individual characteristics of each traffic zone.Therefore,the results can have significant errors.To reduce the forecasting error produced by uniform trip generation rates for different traffic zones,the behavior of each traveler was studied instead of the characteristics of the traffic zone.This paper gives a method for calculating the trip efficiency and the effect of traffic zones combined with a destination selection model based on disaggregate theory for trip generation.Beijing data is used with the trip generation method to predict trip volumes.The results show that the disaggregate model in this paper is more accurate than the traditional method.An analysis of the factors influencing traveler behavior and destination selection shows that the attractiveness of the traffic zone strongly affects the trip generation volume.

  17. Cloth Modeling Based on Particle System

    Institute of Scientific and Technical Information of China (English)

    钟跃崎; 王善元

    2001-01-01

    A physical-based particle system is employed for cloth modeling supported by two basic algorithms, between which one is the construction of the internal and external forces acting on the particle system in terms of KES-F bending and shearing tests, and the other is the collision algorithm of which the collision detection is carried by means of bi-section of time step and the collision response is handled according to the empirical law for frictionless collision With these algorithms. the geometric state of parcles can be expressed as ordinary differential equationswhich is numerically solved by fourth order Runge- Kutta integration. Different draping figures of cotton fabric and wool fabric prove that such a particle system is suitable for 3D cloth modeling and simulation.

  18. Activity based costing model for inventory valuation

    Directory of Open Access Journals (Sweden)

    Vineet Chouhan

    2017-03-01

    Full Text Available Activity-Based-Model (ABC is used for the purpose of significant improvement for overhead accounting systems by providing the best information required for managerial decision. This pa-per discusses implacability of ABC technique on inventory valuation as a management account-ing innovation. In order to prove the applicability of ABC for inventory control a material driven medium-sized and privately owned company from engineering (iron and steel industry is select-ed and by analysis of its production process and its material dependency and use of indirect in-ventory, an ABC model is explored for better inventory control. The case revealed that the ne-cessity of ABC in the area of inventory control is significant. The company is not only able to increase its quality of decision but also it can significantly analyze its cost of direct material cost, valuation of direct material and use its implications for better decision making.

  19. Intercropping enhances productivity and maintains the most soil fertility properties relative to sole cropping.

    Science.gov (United States)

    Wang, Zhi-Gang; Jin, Xin; Bao, Xing-Guo; Li, Xiao-Fei; Zhao, Jian-Hua; Sun, Jian-Hao; Christie, Peter; Li, Long

    2014-01-01

    Yield and nutrient acquisition advantages are frequently found in intercropping systems. However, there are few published reports on soil fertility in intercropping relative to monocultures. A field experiment was therefore established in 2009 in Gansu province, northwest China. The treatments comprised maize/faba bean, maize/soybean, maize/chickpea and maize/turnip intercropping, and their correspoding monocropping. In 2011 (the 3rd year) and 2012 (the 4th year) the yields and some soil chemical properties and enzyme activities were examined after all crop species were harvested or at later growth stages. Both grain yields and nutrient acquisition were significantly greater in all four intercropping systems than corresponding monocropping over two years. Generally, soil organic matter (OM) did not differ significantly from monocropping but did increase in maize/chickpea in 2012 and maize/turnip in both years. Soil total N (TN) did not differ between intercropping and monocropping in either year with the sole exception of maize/faba bean intercropping receiving 80 kg P ha-1 in 2011. Intercropping significantly reduced soil Olsen-P only in 2012, soil exchangeable K in both years, soil cation exchangeable capacity (CEC) in 2012, and soil pH in 2012. In the majority of cases soil enzyme activities did not differ across all the cropping systems at different P application rates compared to monocrops, with the exception of soil acid phosphatase activity which was higher in maize/legume intercropping than in the corresponding monocrops at 40 kg ha-1 P in 2011. P fertilization can alleviate the decline in soil Olsen-P and in soil CEC to some extent. In summary, intercropping enhanced productivity and maintained the majority of soil fertility properties for at least three to four years, especially at suitable P application rates. The results indicate that maize-based intercropping may be an efficient cropping system for sustainable agriculture with carefully managed

  20. Intercropping enhances productivity and maintains the most soil fertility properties relative to sole cropping.

    Directory of Open Access Journals (Sweden)

    Zhi-Gang Wang

    Full Text Available Yield and nutrient acquisition advantages are frequently found in intercropping systems. However, there are few published reports on soil fertility in intercropping relative to monocultures. A field experiment was therefore established in 2009 in Gansu province, northwest China. The treatments comprised maize/faba bean, maize/soybean, maize/chickpea and maize/turnip intercropping, and their correspoding monocropping. In 2011 (the 3rd year and 2012 (the 4th year the yields and some soil chemical properties and enzyme activities were examined after all crop species were harvested or at later growth stages. Both grain yields and nutrient acquisition were significantly greater in all four intercropping systems than corresponding monocropping over two years. Generally, soil organic matter (OM did not differ significantly from monocropping but did increase in maize/chickpea in 2012 and maize/turnip in both years. Soil total N (TN did not differ between intercropping and monocropping in either year with the sole exception of maize/faba bean intercropping receiving 80 kg P ha-1 in 2011. Intercropping significantly reduced soil Olsen-P only in 2012, soil exchangeable K in both years, soil cation exchangeable capacity (CEC in 2012, and soil pH in 2012. In the majority of cases soil enzyme activities did not differ across all the cropping systems at different P application rates compared to monocrops, with the exception of soil acid phosphatase activity which was higher in maize/legume intercropping than in the corresponding monocrops at 40 kg ha-1 P in 2011. P fertilization can alleviate the decline in soil Olsen-P and in soil CEC to some extent. In summary, intercropping enhanced productivity and maintained the majority of soil fertility properties for at least three to four years, especially at suitable P application rates. The results indicate that maize-based intercropping may be an efficient cropping system for sustainable agriculture with carefully

  1. Knowledge-based geometric modeling in construction

    DEFF Research Database (Denmark)

    Bonev, Martin; Hvam, Lars

    2012-01-01

    a considerably high amount of their recourses is required for designing and specifying the majority of their product assortment. As design decisions are hereby based on knowledge and experience about behaviour and applicability of construction techniques and materials for a predefined design situation, smart...... tools need to be developed, to support these activities. In order to achieve a higher degree of design automation, this study proposes a framework for using configuration systems within the CAD environment together with suitable geometric modeling techniques on the example of a Danish manufacturer...

  2. Model-based vision using geometric hashing

    Science.gov (United States)

    Akerman, Alexander, III; Patton, Ronald

    1991-04-01

    The Geometric Hashing technique developed by the NYU Courant Institute has been applied to various automatic target recognition applications. In particular, I-MATH has extended the hashing algorithm to perform automatic target recognition ofsynthetic aperture radar (SAR) imagery. For this application, the hashing is performed upon the geometric locations of dominant scatterers. In addition to being a robust model-based matching algorithm -- invariant under translation, scale, and 3D rotations of the target -- hashing is of particular utility because it can still perform effective matching when the target is partially obscured. Moreover, hashing is very amenable to a SIMD parallel processing architecture, and thus potentially realtime implementable.

  3. Agent-based modeling and simulation

    CERN Document Server

    Taylor, Simon

    2014-01-01

    Operational Research (OR) deals with the use of advanced analytical methods to support better decision-making. It is multidisciplinary with strong links to management science, decision science, computer science and many application areas such as engineering, manufacturing, commerce and healthcare. In the study of emergent behaviour in complex adaptive systems, Agent-based Modelling & Simulation (ABMS) is being used in many different domains such as healthcare, energy, evacuation, commerce, manufacturing and defense. This collection of articles presents a convenient introduction to ABMS with pa

  4. Ontology-Based Model Of Firm Competitiveness

    Science.gov (United States)

    Deliyska, Boryana; Stoenchev, Nikolay

    2010-10-01

    Competitiveness is important characteristics of each business organization (firm, company, corporation etc). It is of great significance for the organization existence and defines evaluation criteria of business success at microeconomical level. Each criterium comprises set of indicators with specific weight coefficients. In the work an ontology-based model of firm competitiveness is presented as a set of several mutually connected ontologies. It would be useful for knowledge structuring, standardization and sharing among experts and software engineers who develop application in the domain. Then the assessment of the competitiveness of various business organizations could be generated more effectively.

  5. Energy-based models for environmental biotechnology.

    Science.gov (United States)

    Rodríguez, Jorge; Lema, Juan M; Kleerebezem, Robbert

    2008-07-01

    Environmental biotechnology is evolving. Current process objectives include the production of chemicals and/or energy carriers (biofuels) in addition to the traditional objective of removing pollutants from waste. To maximise product yields and minimise biomass production, future processes will rely on anaerobic microbial communities. Anaerobic processes are characterised by small Gibbs energy changes in the reactions catalysed, and this provides clear thermodynamic process boundaries. Here, a Gibbs-energy-based methodology is proposed for mathematical modelling of energy-limited anaerobic ecosystems. This methodology provides a basis for the description of microbial activities as a function of environmental factors, which will allow enhanced catalysis of specific reactions of interest for process development.

  6. CSPBuilder - CSP based Scientific Workflow Modelling

    DEFF Research Database (Denmark)

    Friborg, Rune Møllegaard; Vinter, Brian

    2008-01-01

    This paper introduces a framework for building CSP based applications, targeted for clusters and next generation CPU designs. CPUs are produced with several cores today and every future CPU generation will feature increasingly more cores, resulting in a requirement for concurrency that has...... not previously been called for. The framework is CSP presented as a scienti¿c work¿ow model, specialized for scienti¿c computing applications. The purpose of the framework is to enable scientists to exploit large parallel computation resources, which has previously been hard due of the dif¿culty of concurrent...... programming using threads and locks....

  7. Integrated Semantic Similarity Model Based on Ontology

    Institute of Scientific and Technical Information of China (English)

    LIU Ya-Jun; ZHAO Yun

    2004-01-01

    To solve the problem of the inadequacy of semantic processing in the intelligent question answering system, an integrated semantic similarity model which calculates the semantic similarity using the geometric distance and information content is presented in this paper.With the help of interrelationship between concepts, the information content of concepts and the strength of the edges in the ontology network, we can calculate the semantic similarity between two concepts and provide information for the further calculation of the semantic similarity between user's question and answers in knowlegdge base.The results of the experiments on the prototype have shown that the semantic problem in natural language processing can also be solved with the help of the knowledge and the abundant semantic information in ontology.More than 90% accuracy with less than 50 ms average searching time in the intelligent question answering prototype system based on ontology has been reached.The result is very satisfied.

  8. Causality, mathematical models and statistical association: dismantling evidence-based medicine.

    Science.gov (United States)

    Thompson, R Paul

    2010-04-01

    From humble beginnings, largely at the medical school at McMaster University, Canada, the evidence-based medicine (EBM) movement has enjoyed a spectacular rise in international acceptance over the last 25 years. Randomized controlled trials (RCTs) and systematic reviews based on them have pride of place (the gold standard) in EBM's hierarchy of evidence; models and theories are relegated to the bottom of the hierarchy. In the last decade, RCTs have been extensively criticized. I briefly rehearse those criticisms because they are an important backdrop to the criticism of EBM developed in this paper. In essence, the argument developed here is that RCTs use mathematics solely as a tool of analysis rather than as the language of the science and that this fundamentally affects the validity of causal claims. As EBM gives pride of place to RCTs and devalues theoretical models - a devaluation that would be incomprehensible to a physicist or biologist - the validity of EBM's causal claims and knowledge claims are weak and far from a 'gold standard'.

  9. Python-Based Applications for Hydrogeological Modeling

    Science.gov (United States)

    Khambhammettu, P.

    2013-12-01

    Python is a general-purpose, high-level programming language whose design philosophy emphasizes code readability. Add-on packages supporting fast array computation (numpy), plotting (matplotlib), scientific /mathematical Functions (scipy), have resulted in a powerful ecosystem for scientists interested in exploratory data analysis, high-performance computing and data visualization. Three examples are provided to demonstrate the applicability of the Python environment in hydrogeological applications. Python programs were used to model an aquifer test and estimate aquifer parameters at a Superfund site. The aquifer test conducted at a Groundwater Circulation Well was modeled with the Python/FORTRAN-based TTIM Analytic Element Code. The aquifer parameters were estimated with PEST such that a good match was produced between the simulated and observed drawdowns. Python scripts were written to interface with PEST and visualize the results. A convolution-based approach was used to estimate source concentration histories based on observed concentrations at receptor locations. Unit Response Functions (URFs) that relate the receptor concentrations to a unit release at the source were derived with the ATRANS code. The impact of any releases at the source could then be estimated by convolving the source release history with the URFs. Python scripts were written to compute and visualize receptor concentrations for user-specified source histories. The framework provided a simple and elegant way to test various hypotheses about the site. A Python/FORTRAN-based program TYPECURVEGRID-Py was developed to compute and visualize groundwater elevations and drawdown through time in response to a regional uniform hydraulic gradient and the influence of pumping wells using either the Theis solution for a fully-confined aquifer or the Hantush-Jacob solution for a leaky confined aquifer. The program supports an arbitrary number of wells that can operate according to arbitrary schedules. The

  10. Biologically based multistage modeling of radiation effects

    Energy Technology Data Exchange (ETDEWEB)

    William Hazelton; Suresh Moolgavkar; E. Georg Luebeck

    2005-08-30

    This past year we have made substantial progress in modeling the contribution of homeostatic regulation to low-dose radiation effects and carcinogenesis. We have worked to refine and apply our multistage carcinogenesis models to explicitly incorporate cell cycle states, simple and complex damage, checkpoint delay, slow and fast repair, differentiation, and apoptosis to study the effects of low-dose ionizing radiation in mouse intestinal crypts, as well as in other tissues. We have one paper accepted for publication in ''Advances in Space Research'', and another manuscript in preparation describing this work. I also wrote a chapter describing our combined cell-cycle and multistage carcinogenesis model that will be published in a book on stochastic carcinogenesis models edited by Wei-Yuan Tan. In addition, we organized and held a workshop on ''Biologically Based Modeling of Human Health Effects of Low dose Ionizing Radiation'', July 28-29, 2005 at Fred Hutchinson Cancer Research Center in Seattle, Washington. We had over 20 participants, including Mary Helen Barcellos-Hoff as keynote speaker, talks by most of the low-dose modelers in the DOE low-dose program, experimentalists including Les Redpath (and Mary Helen), Noelle Metting from DOE, and Tony Brooks. It appears that homeostatic regulation may be central to understanding low-dose radiation phenomena. The primary effects of ionizing radiation (IR) are cell killing, delayed cell cycling, and induction of mutations. However, homeostatic regulation causes cells that are killed or damaged by IR to eventually be replaced. Cells with an initiating mutation may have a replacement advantage, leading to clonal expansion of these initiated cells. Thus we have focused particularly on modeling effects that disturb homeostatic regulation as early steps in the carcinogenic process. There are two primary considerations that support our focus on homeostatic regulation. First, a number of

  11. Model based control of refrigeration systems

    Energy Technology Data Exchange (ETDEWEB)

    Sloth Larsen, L.F.

    2005-11-15

    The subject for this Ph.D. thesis is model based control of refrigeration systems. Model based control covers a variety of different types of controls, that incorporates mathematical models. In this thesis the main subject therefore has been restricted to deal with system optimizing control. The optimizing control is divided into two layers, where the system oriented top layers deals with set-point optimizing control and the lower layer deals with dynamical optimizing control in the subsystems. The thesis has two main contributions, i.e. a novel approach for set-point optimization and a novel approach for desynchronization based on dynamical optimization. The focus in the development of the proposed set-point optimizing control has been on deriving a simple and general method, that with ease can be applied on various compositions of the same class of systems, such as refrigeration systems. The method is based on a set of parameter depended static equations describing the considered process. By adapting the parameters to the given process, predict the steady state and computing a steady state gradient of the cost function, the process can be driven continuously towards zero gradient, i.e. the optimum (if the cost function is convex). The method furthermore deals with system constrains by introducing barrier functions, hereby the best possible performance taking the given constrains in to account can be obtained, e.g. under extreme operational conditions. The proposed method has been applied on a test refrigeration system, placed at Aalborg University, for minimization of the energy consumption. Here it was proved that by using general static parameter depended system equations it was possible drive the set-points close to the optimum and thus reduce the power consumption with up to 20%. In the dynamical optimizing layer the idea is to optimize the operation of the subsystem or the groupings of subsystems, that limits the obtainable system performance. In systems

  12. Modeling Web-based Educational Systems: Process Design Teaching Model

    Directory of Open Access Journals (Sweden)

    Elena Rokou

    2004-01-01

    Full Text Available Using modeling languages is essential to the construction of educational systems based on software engineering principles and methods. Furthermore, the instructional design is undoubtedly the cornerstone of the design and development of educational systems. Although several methodologies and languages have been proposed for the specification of isolated educational multimedia systems, none has optimum results for the description of these systems and, especially, for their pedagogical aspect. Of course this is due primarily to how these systems function and are applied; it is not due to the language itself, although its special characteristics contribute substantially to the development of these systems sometimes positively and sometimes negatively. In this paper, we briefly describe the introduction of stereotypes to the pedagogical design of educational systems and appropriate modifications of the existing package diagrams of UML (Unified Modeling Language. The main objective of these new stereotypes is to describe sufficiently the mechanisms of generation, monitoring and re-adapting of teaching and student’s models which can be used in the educational applications.

  13. Shifts in the timing of spawning in sole linked to warming sea temperatures

    NARCIS (Netherlands)

    Fincham, J.I.; Rijnsdorp, A.D.; Engelhard, G.H.

    2013-01-01

    Phenotypic traits such as peak spawning time may vary within and differ between populations in relation to environmental factors, such as temperature. Sole (Solea solea) is a valuable, commercially exploited species that spawns in late winter or spring. The date of peak spawning was estimated for ea

  14. 40 CFR 1054.620 - What are the provisions for exempting engines used solely for competition?

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 32 2010-07-01 2010-07-01 false What are the provisions for exempting engines used solely for competition? 1054.620 Section 1054.620 Protection of Environment ENVIRONMENTAL... competition teams, professional competitors, or other qualified competitors. For replacement engines, the...

  15. 75 FR 53269 - Federal Acquisition Regulation; Tribal Consultation; Justification and Approval of Sole-Source 8...

    Science.gov (United States)

    2010-08-31

    ... Authorization Act (NDAA) for FY 2010, Public Law 111-84. Section 811 addresses requirements for the justification and approval of sole-source contracts over $20 million under the 8(a) small business development... business under the Small Business Administration's 8(a) business development program, including...

  16. [Forces acting on foot soles during stair climbing in healthy probands and in patients with coxarthrosis].

    Science.gov (United States)

    Savvidis, E; von der Decken, C B

    1999-04-01

    We investigated the contact forces acting on the sole of the foot of healthy persons and coxarthrosis patients climbing and descending stairs. The sole contact forces were determined using an experimental set-up comprising a stair construction provided with an integrated measuring step. In healthy subjects, the forces acting on the soles of the feet while climbing stairs were found to be 1.2 times their body weight. With regard to descending stairs, a distinction must be made between "hard" and "soft" walkers. In the case of "hard" walkers, the forces acting on the soles may be as much as 2.6 times body weight. These forces can be reduced by the wearing of shock-absorbing shoes. In coxarthrosis and prostheses-bearing patients, all movements are executed more slowly when climbing or descending stairs, so that only small dynamic forces arise. The greatest loads are about 1.2 times the patient's own weight. In these patients, an effective reduction by shockabsorbing footwear is not possible.

  17. Comparative Economic Study of Mixed and Sole Cassava Cropping Systems in Nigeria

    Directory of Open Access Journals (Sweden)

    J. O. Ajayi

    2014-12-01

    Full Text Available Agricultural economists continue to argue if mixed or sole cassava cropping system is more economically profitable and in terms of yield and returns to farmers particularly for Nigeria which is the world’s largest producer of the crop. The study was carried out to analyse the economics comparatively of mixed and sole cassava cropping systems in Nigeria. The study made use of both primary and secondary data. Primary data were collected with the aid of well-structured questionnaires assisted with interview schedules. Field data collection was conducted between March and April, 2014. Multi-stage sampling technique was used to select four hundred and eighty (480 respondents across the six major cassava-producing states in Nigeria (Benue, Cross Rivers, Enugu, Kogi, Ondo, and Oyo. Data collected were analysed using descriptive statistics and comparative budgetary analysis. The study showed that mixed cropping system is more male-dominated than sole cropping system. The study also revealed that sole cassava cropping system is more economically profitable than mixed cassava cropping system while the later provides opportunities of all-year-round farm incomes to serve as a better poverty- alleviating mechanism.

  18. A measurement-based generalized source model for Monte Carlo dose simulations of CT scans

    Science.gov (United States)

    Ming, Xin; Feng, Yuanming; Liu, Ransheng; Yang, Chengwen; Zhou, Li; Zhai, Hezheng; Deng, Jun

    2017-03-01

    The goal of this study is to develop a generalized source model for accurate Monte Carlo dose simulations of CT scans based solely on the measurement data without a priori knowledge of scanner specifications. The proposed generalized source model consists of an extended circular source located at x-ray target level with its energy spectrum, source distribution and fluence distribution derived from a set of measurement data conveniently available in the clinic. Specifically, the central axis percent depth dose (PDD) curves measured in water and the cone output factors measured in air were used to derive the energy spectrum and the source distribution respectively with a Levenberg–Marquardt algorithm. The in-air film measurement of fan-beam dose profiles at fixed gantry was back-projected to generate the fluence distribution of the source model. A benchmarked Monte Carlo user code was used to simulate the dose distributions in water with the developed source model as beam input. The feasibility and accuracy of the proposed source model was tested on a GE LightSpeed and a Philips Brilliance Big Bore multi-detector CT (MDCT) scanners available in our clinic. In general, the Monte Carlo simulations of the PDDs in water and dose profiles along lateral and longitudinal directions agreed with the measurements within 4%/1 mm for both CT scanners. The absolute dose comparison using two CTDI phantoms (16 cm and 32 cm in diameters) indicated a better than 5% agreement between the Monte Carlo-simulated and the ion chamber-measured doses at a variety of locations for the two scanners. Overall, this study demonstrated that a generalized source model can be constructed based only on a set of measurement data and used for accurate Monte Carlo dose simulations of patients’ CT scans, which would facilitate patient-specific CT organ dose estimation and cancer risk management in the diagnostic and therapeutic radiology.

  19. Pilot Testing of a Sampling Methodology for Assessing Seed Attachment Propensity and Transport Rate in a Soil Matrix Carried on Boot Soles and Bike Tires

    Science.gov (United States)

    Hardiman, Nigel; Dietz, Kristina Charlotte; Bride, Ian; Passfield, Louis

    2017-01-01

    Land managers of natural areas are under pressure to balance demands for increased recreation access with protection of the natural resource. Unintended dispersal of seeds by visitors to natural areas has high potential for weedy plant invasions, with initial seed attachment an important step in the dispersal process. Although walking and mountain biking are popular nature-based recreation activities, there are few studies quantifying propensity for seed attachment and transport rate on boot soles and none for bike tires. Attachment and transport rate can potentially be affected by a wide range of factors for which field testing can be time-consuming and expensive. We pilot tested a sampling methodology for measuring seed attachment and transport rate in a soil matrix carried on boot soles and bike tires traversing a known quantity and density of a seed analog (beads) over different distances and soil conditions. We found % attachment rate on boot soles was much lower overall than previously reported, but that boot soles had a higher propensity for seed attachment than bike tires in almost all conditions. We believe our methodology offers a cost-effective option for researchers seeking to manipulate and test effects of different influencing factors on these two dispersal vectors.

  20. Agent-based modelling in synthetic biology.

    Science.gov (United States)

    Gorochowski, Thomas E

    2016-11-30

    Biological systems exhibit complex behaviours that emerge at many different levels of organization. These span the regulation of gene expression within single cells to the use of quorum sensing to co-ordinate the action of entire bacterial colonies. Synthetic biology aims to make the engineering of biology easier, offering an opportunity to control natural systems and develop new synthetic systems with useful prescribed behaviours. However, in many cases, it is not understood how individual cells should be programmed to ensure the emergence of a required collective behaviour. Agent-based modelling aims to tackle this problem, offering a framework in which to simulate such systems and explore cellular design rules. In this article, I review the use of agent-based models in synthetic biology, outline the available computational tools, and provide details on recently engineered biological systems that are amenable to this approach. I further highlight the challenges facing this methodology and some of the potential future directions. © 2016 The Author(s).

  1. Models-Based Practice: Great White Hope or White Elephant?

    Science.gov (United States)

    Casey, Ashley

    2014-01-01

    Background: Many critical curriculum theorists in physical education have advocated a model- or models-based approach to teaching in the subject. This paper explores the literature base around models-based practice (MBP) and asks if this multi-models approach to curriculum planning has the potential to be the great white hope of pedagogical change…

  2. Models-Based Practice: Great White Hope or White Elephant?

    Science.gov (United States)

    Casey, Ashley

    2014-01-01

    Background: Many critical curriculum theorists in physical education have advocated a model- or models-based approach to teaching in the subject. This paper explores the literature base around models-based practice (MBP) and asks if this multi-models approach to curriculum planning has the potential to be the great white hope of pedagogical change…

  3. Physics-Based Correction of Inhomogeneities in Temperature Series: Model Transferability Testing and Comparison to Statistical Approaches

    Science.gov (United States)

    Auchmann, Renate; Brönnimann, Stefan; Croci-Maspoli, Mischa

    2016-04-01

    For the correction of inhomogeneities in sub-daily temperature series, Auchmann and Brönnimann (2012) developed a physics-based model for one specific type of break, i.e. the transition from a Wild screen to a Stevenson screen at one specific station in Basel, Switzerland. The model is based solely on physical considerations, no relationships of the covariates to the differences between the parallel measurements have been investigated. The physics-based model requires detailed information on the screen geometry, the location, and includes a variety of covariates in the model. The model is mainly based on correcting the radiation error, including a modification by ambient wind. In this study we test the application of the model to another station, Zurich, experiencing the same type of transition. Furthermore we compare the performance of the physics based correction to purely statistical correction approaches (constant correction, correcting for annual cycle using spline). In Zurich the Wild screen was replaced in 1954 by the Stevenson screen, from 1954-1960 parallel temperature measurements in both screens were taken, which will be used to assess the performance of the applied corrections. For Zurich the required model input is available (i.e. three times daily observations of wind, cloud cover, pressure and humidity measurements, local times of sunset and sunrise). However, a large number of stations do not measure these additional input data required for the model, which hampers the transferability and applicability of the model to other stations. Hence, we test possible simplifications and generalizations of the model to make it more easily applicable to stations with the same type of inhomogeneity. In a last step we test whether other types of transitions (e.g., from a Stevenson screen to an automated weather system) can be corrected using the principle of a physics-based approach.

  4. Intellectual Model-Based Configuration Management Conception

    Directory of Open Access Journals (Sweden)

    Bartusevics Arturs

    2014-07-01

    Full Text Available Software configuration management is one of the most important disciplines within the software development project, which helps control the software evolution process and allows including into the end project only tested and validated changes. To achieve this, software management completes certain tasks. Concrete tools are used for technical implementation of tasks, such as version control systems, servers of continuous integration, compilers, etc. A correct configuration management process usually requires several tools, which mutually exchange information by generating various kinds of transfers. When it comes to introducing the configuration management process, often there are situations when tool installation is started, yet at that given moment there is no general picture of the total process. The article offers a model-based configuration management concept, which foresees the development of an abstract model for the configuration management process that later is transformed to lower abstraction level models and tools are indicated to support the technical process. A solution of this kind allows a more rational introduction and configuration of tools

  5. Model-based estimation of individual fitness

    Science.gov (United States)

    Link, W.A.; Cooch, E.G.; Cam, E.

    2002-01-01

    Fitness is the currency of natural selection, a measure of the propagation rate of genotypes into future generations. Its various definitions have the common feature that they are functions of survival and fertility rates. At the individual level, the operative level for natural selection, these rates must be understood as latent features, genetically determined propensities existing at birth. This conception of rates requires that individual fitness be defined and estimated by consideration of the individual in a modelled relation to a group of similar individuals; the only alternative is to consider a sample of size one, unless a clone of identical individuals is available. We present hierarchical models describing individual heterogeneity in survival and fertility rates and allowing for associations between these rates at the individual level. We apply these models to an analysis of life histories of Kittiwakes (Rissa tridactyla ) observed at several colonies on the Brittany coast of France. We compare Bayesian estimation of the population distribution of individual fitness with estimation based on treating individual life histories in isolation, as samples of size one (e.g. McGraw & Caswell, 1996).

  6. Evaluating face trustworthiness: a model based approach.

    Science.gov (United States)

    Todorov, Alexander; Baron, Sean G; Oosterhof, Nikolaas N

    2008-06-01

    Judgments of trustworthiness from faces determine basic approach/avoidance responses and approximate the valence evaluation of faces that runs across multiple person judgments. Here, based on trustworthiness judgments and using a computer model for face representation, we built a model for representing face trustworthiness (study 1). Using this model, we generated novel faces with an increased range of trustworthiness and used these faces as stimuli in a functional Magnetic Resonance Imaging study (study 2). Although participants did not engage in explicit evaluation of the faces, the amygdala response changed as a function of face trustworthiness. An area in the right amygdala showed a negative linear response-as the untrustworthiness of faces increased so did the amygdala response. Areas in the left and right putamen, the latter area extended into the anterior insula, showed a similar negative linear response. The response in the left amygdala was quadratic--strongest for faces on both extremes of the trustworthiness dimension. The medial prefrontal cortex and precuneus also showed a quadratic response, but their response was strongest to faces in the middle range of the trustworthiness dimension.

  7. Fast Algorithms for Model-Based Diagnosis

    Science.gov (United States)

    Fijany, Amir; Barrett, Anthony; Vatan, Farrokh; Mackey, Ryan

    2005-01-01

    Two improved new methods for automated diagnosis of complex engineering systems involve the use of novel algorithms that are more efficient than prior algorithms used for the same purpose. Both the recently developed algorithms and the prior algorithms in question are instances of model-based diagnosis, which is based on exploring the logical inconsistency between an observation and a description of a system to be diagnosed. As engineering systems grow more complex and increasingly autonomous in their functions, the need for automated diagnosis increases concomitantly. In model-based diagnosis, the function of each component and the interconnections among all the components of the system to be diagnosed (for example, see figure) are represented as a logical system, called the system description (SD). Hence, the expected behavior of the system is the set of logical consequences of the SD. Faulty components lead to inconsistency between the observed behaviors of the system and the SD. The task of finding the faulty components (diagnosis) reduces to finding the components, the abnormalities of which could explain all the inconsistencies. Of course, the meaningful solution should be a minimal set of faulty components (called a minimal diagnosis), because the trivial solution, in which all components are assumed to be faulty, always explains all inconsistencies. Although the prior algorithms in question implement powerful methods of diagnosis, they are not practical because they essentially require exhaustive searches among all possible combinations of faulty components and therefore entail the amounts of computation that grow exponentially with the number of components of the system.

  8. Activity Recognition Using Biomechanical Model Based Pose Estimation

    OpenAIRE

    Reiss, Attila; Hendeby, Gustaf; Bleser, Gabriele; Stricker, Didier

    2010-01-01

    In this paper, a novel activity recognition method based on signal-oriented and model-based features is presented. The model-based features are calculated from shoulder and elbow joint angles and torso orientation, provided by upper-body pose estimation based on a biomechanical body model. The recognition performance of signal-oriented and model-based features is compared within this paper, and the potential of improving recognition accuracy by combining the two approaches is proved: the accu...

  9. Semi-Empirical Models for Buoyancy-Driven Ventilation

    DEFF Research Database (Denmark)

    Terpager Andersen, Karl

    2015-01-01

    A literature study is presented on the theories and models dealing with buoyancy-driven ventilation in rooms. The models are categorised into four types according to how the physical process is conceived: column model, fan model, neutral plane model and pressure model. These models are analysed...... and compared with a reference model. Discrepancies and differences are shown, and the deviations are discussed. It is concluded that a reliable buoyancy model based solely on the fundamental flow equations is desirable....

  10. 我国外商直接投资企业技术外溢效应的实证研究——基于合资、合作、独资模式的比较分析%The Empirical Analysis on the FDI Technology Spillovers——Based on the Joint Venture, Cooperation, Sole Pattern Comparative Analysis

    Institute of Scientific and Technical Information of China (English)

    林玲; 余娟娟

    2012-01-01

      Considering the foreign capital admittance model on FDI technology spillover effect, using the segmentation method of inspection from overall level testing China's FDI in three different stages of technological spillover effect sizes from FDI structure level test and comparison of three kinds of foreign investment access mode (Sino-foreign cooperation, Sino-foreign joint ventures, foreign-owned) FDI technology spillover effect size. The results showed that: different foreign entry mode, FDI technology spillover efficiency differences exist, including Sino-foreign joint maximum, followed by foreign-owned, finally is Sino-foreign cooperation. China's current foreign trader "owned" trend is not in favor of FDI technology spillover effect of foreign policy should play, in the light of its general trend, draw on the advantages and avoid disadvantages.%  考虑到外资准入模式对FDI技术外溢效应的影响,利用分段检验的方法从总量层面检验了我国FDI在三个不同发展阶段上技术外溢效应的大小从FDI结构层面检验并比较了三种外资准入模式下(中外合作、中外合资、外商独资)FDI技术外溢效应的大小。结果显示:不同的外资准入模式下,FDI的技术溢出效率存在差异,其中中外合资最大,其次是外商独资,最后是中外合作。我国当前外商“独资化”趋势不利于FDI技术溢出效应的发挥,外资政策应因势利导、趋利避害。

  11. Groundwater flow pattern and related environmental phenomena in complex geologic setting based on integrated model construction

    Science.gov (United States)

    Tóth, Ádám; Havril, Tímea; Simon, Szilvia; Galsa, Attila; Monteiro Santos, Fernando A.; Müller, Imre; Mádl-Szőnyi, Judit

    2016-08-01

    Groundwater flow, driven, controlled and determined by topography, geology and climate, is responsible for several natural surface manifestations and affected by anthropogenic processes. Therefore, flowing groundwater can be regarded as an environmental agent. Numerical simulation of groundwater flow could reveal the flow pattern and explain the observed features. In complex geologic framework, where the geologic-hydrogeologic knowledge is limited, the groundwater flow model could not be constructed based solely on borehole data, but geophysical information could aid the model building. The integrated model construction was presented via the case study of the Tihany Peninsula, Hungary, with the aims of understanding the background and occurrence of groundwater-related environmental phenomena, such as wetlands, surface water-groundwater interaction, slope instability, and revealing the potential effect of anthropogenic activity and climate change. The hydrogeologic model was prepared on the basis of the compiled archive geophysical database and the results of recently performed geophysical measurements complemented with geologic-hydrogeologic data. Derivation of different electrostratigraphic units, revealing fracturing and detecting tectonic elements was achieved by systematically combined electromagnetic geophysical methods. The deduced information can be used as model input for groundwater flow simulation concerning hydrostratigraphy, geometry and boundary conditions. The results of numerical modelling were interpreted on the basis of gravity-driven regional groundwater flow concept and validated by field mapping of groundwater-related phenomena. The 3D model clarified the hydraulic behaviour of the formations, revealed the subsurface hydraulic connection between groundwater and wetlands and displayed the groundwater discharge pattern, as well. The position of wetlands, their vegetation type, discharge features and induced landslides were explained as

  12. Use of a Microsoft Excel based add-in program to calculate plasma sinistrin clearance by a two-compartment model analysis in dogs.

    Science.gov (United States)

    Steinbach, Sarah M L; Sturgess, Christopher P; Dunning, Mark D; Neiger, Reto

    2015-06-01

    Assessment of renal function by means of plasma clearance of a suitable marker has become standard procedure for estimation of glomerular filtration rate (GFR). Sinistrin, a polyfructan solely cleared by the kidney, is often used for this purpose. Pharmacokinetic modeling using adequate software is necessary to calculate disappearance rate and half-life of sinistrin. The purpose of this study was to describe the use of a Microsoft excel based add-in program to calculate plasma sinistrin clearance, as well as additional pharmacokinetic parameters such as transfer rates (k), half-life (t1/2) and volume of distribution (Vss) for sinistrin in dogs with varying degrees of renal function.

  13. An Attack Modeling Based on Colored Petri Net

    Institute of Scientific and Technical Information of China (English)

    ZHOU Shijie; QIN Zhiguang; ZHANG Feng; LIU Jinde

    2004-01-01

    A color petri net (CPN) based attack modeling approach is addressed.Compared with graph-based modeling,CPN based attack model is fiexible enough to model Intemet intrusions,because of their static and dynamic features.The processes and rules of building CPN based attack model from attack tree are also presented.In order to evaluate the risk of intrusion,some cost elements are added to CPN based attack modeling.This extended model is useful in intrusion detection and risk evaluation.Experiences show that it is easy to exploit CPN based attack modeling approach to provide the controlling functions,such as intrusion response and intrusion defense.A case study given in this paper shows that CPN based attack model has many unique characters which attack tree model hasn't.

  14. A DNA-based semantic fusion model for remote sensing data.

    Directory of Open Access Journals (Sweden)

    Heng Sun

    Full Text Available Semantic technology plays a key role in various domains, from conversation understanding to algorithm analysis. As the most efficient semantic tool, ontology can represent, process and manage the widespread knowledge. Nowadays, many researchers use ontology to collect and organize data's semantic information in order to maximize research productivity. In this paper, we firstly describe our work on the development of a remote sensing data ontology, with a primary focus on semantic fusion-driven research for big data. Our ontology is made up of 1,264 concepts and 2,030 semantic relationships. However, the growth of big data is straining the capacities of current semantic fusion and reasoning practices. Considering the massive parallelism of DNA strands, we propose a novel DNA-based semantic fusion model. In this model, a parallel strategy is developed to encode the semantic information in DNA for a large volume of remote sensing data. The semantic information is read in a parallel and bit-wise manner and an individual bit is converted to a base. By doing so, a considerable amount of conversion time can be saved, i.e., the cluster-based multi-processes program can reduce the conversion time from 81,536 seconds to 4,937 seconds for 4.34 GB source data files. Moreover, the size of result file recording DNA sequences is 54.51 GB for parallel C program compared with 57.89 GB for sequential Perl. This shows that our parallel method can also reduce the DNA synthesis cost. In addition, data types are encoded in our model, which is a basis for building type system in our future DNA computer. Finally, we describe theoretically an algorithm for DNA-based semantic fusion. This algorithm enables the process of integration of the knowledge from disparate remote sensing data sources into a consistent, accurate, and complete representation. This process depends solely on ligation reaction and screening operations instead of the ontology.

  15. A DNA-based semantic fusion model for remote sensing data.

    Science.gov (United States)

    Sun, Heng; Weng, Jian; Yu, Guangchuang; Massawe, Richard H

    2013-01-01

    Semantic technology plays a key role in various domains, from conversation understanding to algorithm analysis. As the most efficient semantic tool, ontology can represent, process and manage the widespread knowledge. Nowadays, many researchers use ontology to collect and organize data's semantic information in order to maximize research productivity. In this paper, we firstly describe our work on the development of a remote sensing data ontology, with a primary focus on semantic fusion-driven research for big data. Our ontology is made up of 1,264 concepts and 2,030 semantic relationships. However, the growth of big data is straining the capacities of current semantic fusion and reasoning practices. Considering the massive parallelism of DNA strands, we propose a novel DNA-based semantic fusion model. In this model, a parallel strategy is developed to encode the semantic information in DNA for a large volume of remote sensing data. The semantic information is read in a parallel and bit-wise manner and an individual bit is converted to a base. By doing so, a considerable amount of conversion time can be saved, i.e., the cluster-based multi-processes program can reduce the conversion time from 81,536 seconds to 4,937 seconds for 4.34 GB source data files. Moreover, the size of result file recording DNA sequences is 54.51 GB for parallel C program compared with 57.89 GB for sequential Perl. This shows that our parallel method can also reduce the DNA synthesis cost. In addition, data types are encoded in our model, which is a basis for building type system in our future DNA computer. Finally, we describe theoretically an algorithm for DNA-based semantic fusion. This algorithm enables the process of integration of the knowledge from disparate remote sensing data sources into a consistent, accurate, and complete representation. This process depends solely on ligation reaction and screening operations instead of the ontology.

  16. Context Based Reasoning in Business Process Models

    OpenAIRE

    Balabko, Pavel; Wegmann, Alain

    2003-01-01

    Modeling approaches often are not adapted to human reasoning: models are ambiguous and imprecise. A same model element may have multiple meanings in different functional roles of a system. Existing modeling approaches do not relate explicitly these functional roles with model elements. A principle that can solve this problem is that model elements should be defined in a context. We believe that the explicit modeling of context is especially useful in Business Process Modeling (BPM) where the ...

  17. Structure-Function Relationship of a Plant NCS1 Member - Homology Modeling and Mutagenesis Identified Residues Critical for Substrate Specificity of PLUTO, a Nucleobase Transporter from Arabidopsis: e91343

    National Research Council Canada - National Science Library

    Sandra Witz; Pankaj Panwar; Markus Schober; Johannes Deppe; Farhan Ahmad Pasha; M Joanne Lemieux; Torsten Möhlmann

    2014-01-01

    .... We present the first homology model of PLUTO, the sole plant NCS1 member from Arabidopsis based on the crystal structure of the benzyl hydantoin transporter MHP1 from Microbacterium liquefaciens...

  18. A Collective Case Study of Secondary Students' Model-Based Inquiry on Natural Selection through Programming in an Agent-Based Modeling Environment

    Science.gov (United States)

    Xiang, Lin

    incomplete and many relationships among the model ideas had not been well established by the end of the study. Most of them did not treat the natural selection model as a whole but only focused on some ideas within the model. Very few of them could scientifically apply the natural selection model to interpret other evolutionary phenomena. The findings about participating students' programming processes revealed these processes were composed of consecutive programming cycles. The cycle typically included posing a task, constructing and running program codes, and examining the resulting simulation. Students held multiple ideas and applied various programming strategies in these cycles. Students were involved in MBI at each step of a cycle. Three types of ideas, six programming strategies and ten MBI actions were identified out of the processes. The relationships among these ideas, strategies and actions were also identified and described. Findings suggested that ABPM activities could support MBI by (1) exposing students' personal models and understandings, (2) provoking and supporting a series of model-based inquiry activities, such as elaborating target phenomena, abstracting patterns, and revising conceptual models, and (3) provoking and supporting tangible and productive conversations among students, as well as between the instructor and students. Findings also revealed three programming behaviors that appeared to impede productive MBI, including (1) solely phenomenon-orientated programming, (2) transplanting program codes, and (3) blindly running procedures. Based on the findings, I propose a general modeling process in ABPM activities, summarize the ways in which MBI can be supported in ABPM activities and constrained by multiple factors, and suggest the implications of this study in the future ABPM-assisted science instructional design and research.

  19. Ecosystem Based Business Model of Smart Grid

    DEFF Research Database (Denmark)

    Lundgaard, Morten Raahauge; Ma, Zheng; Jørgensen, Bo Nørregaard

    2015-01-01

    This paper tries to investigate the ecosystem based business model in a smart grid infrastructure and the potential of value capture in the highly complex macro infrastructure such as smart grid. This paper proposes an alternative perspective to study the smart grid business ecosystem to support...... the infrastructural challenges, such as the interoperability of business components for smart grid. So far little research has explored the business ecosystem in the smart grid concept. The study on the smart grid with the theory of business ecosystem may open opportunities to understand market catalysts. This study...... contributes an understanding of business ecosystem applicable for smart grid. Smart grid infrastructure is an intricate business ecosystem, which have several intentions to deliver the value proposition and what it should be. The findings help to identify and capture value from markets....

  20. Model-based control of networked systems

    CERN Document Server

    Garcia, Eloy; Montestruque, Luis A

    2014-01-01

    This monograph introduces a class of networked control systems (NCS) called model-based networked control systems (MB-NCS) and presents various architectures and control strategies designed to improve the performance of NCS. The overall performance of NCS considers the appropriate use of network resources, particularly network bandwidth, in conjunction with the desired response of the system being controlled.   The book begins with a detailed description of the basic MB-NCS architecture that provides stability conditions in terms of state feedback updates . It also covers typical problems in NCS such as network delays, network scheduling, and data quantization, as well as more general control problems such as output feedback control, nonlinear systems stabilization, and tracking control.   Key features and topics include: Time-triggered and event-triggered feedback updates Stabilization of uncertain systems subject to time delays, quantization, and extended absence of feedback Optimal control analysis and ...

  1. Model Based Control of Refrigeration Systems

    DEFF Research Database (Denmark)

    Larsen, Lars Finn Sloth

    of the supermarket refrigeration systems therefore greatly relies on a human operator to detect and accommodate failures, and to optimize system performance under varying operational condition. Today these functions are maintained by monitoring centres located all over the world. Initiated by the growing need...... for automation of these procedures, that is to incorporate some "intelligence" in the control system, this project was started up. The main emphasis of this work has been on model based methods for system optimizing control in supermarket refrigeration systems. The idea of implementing a system optimizing.......e. by degrading the performance. The method has been successfully applied on a test frigeration system for minimization of the power consumption; the hereby gained experimental results will be presented. The present control structure in a supermarket refrigeration system is distributed, which means...

  2. Model based optimization of EMC input filters

    Energy Technology Data Exchange (ETDEWEB)

    Raggl, K; Kolar, J. W. [Swiss Federal Institute of Technology, Power Electronic Systems Laboratory, Zuerich (Switzerland); Nussbaumer, T. [Levitronix GmbH, Zuerich (Switzerland)

    2008-07-01

    Input filters of power converters for compliance with regulatory electromagnetic compatibility (EMC) standards are often over-dimensioned in practice due to a non-optimal selection of number of filter stages and/or the lack of solid volumetric models of the inductor cores. This paper presents a systematic filter design approach based on a specific filter attenuation requirement and volumetric component parameters. It is shown that a minimal volume can be found for a certain optimal number of filter stages for both the differential mode (DM) and common mode (CM) filter. The considerations are carried out exemplarily for an EMC input filter of a single phase power converter for the power levels of 100 W, 300 W, and 500 W. (author)

  3. Molecular Method for Sex Identification of Half-Smooth Tongue Sole (Cynoglossus semilaevis Using a Novel Sex-Linked Microsatellite Marker

    Directory of Open Access Journals (Sweden)

    Xiaolin Liao

    2014-07-01

    Full Text Available Half-smooth tongue sole (Cynoglossus semilaevis is one of the most important flatfish species for aquaculture in China. To produce a monosex population, we attempted to develop a marker-assisted sex control technique in this sexually size dimorphic fish. In this study, we identified a co-dominant sex-linked marker (i.e., CyseSLM by screening genomic microsatellites and further developed a novel molecular method for sex identification in the tongue sole. CyseSLM has a sequence similarity of 73%–75% with stickleback, medaka, Fugu and Tetraodon. At this locus, two alleles (i.e., A244 and A234 were amplified from 119 tongue sole individuals with primer pairs CyseSLM-F1 and CyseSLM-R. Allele A244 was present in all individuals, while allele A234 (female-associated allele, FAA was mostly present in females with exceptions in four male individuals. Compared with the sequence of A244, A234 has a 10-bp deletion and 28 SNPs. A specific primer (CyseSLM-F2 was then designed based on the A234 sequence, which amplified a 204 bp fragment in all females and four males with primer CyseSLM-R. A time-efficient multiplex PCR program was developed using primers CyseSLM-F2, CyseSLM-R and the newly designed primer CyseSLM-F3. The multiplex PCR products with co-dominant pattern could be detected by agarose gel electrophoresis, which accurately identified the genetic sex of the tongue sole. Therefore, we have developed a rapid and reliable method for sex identification in tongue sole with a newly identified sex-linked microsatellite marker.

  4. Disulfide Connectivity Prediction Based on Modelled Protein 3D Structural Information and Random Forest Regression.

    Science.gov (United States)

    Yu, Dong-Jun; Li, Yang; Hu, Jun; Yang, Xibei; Yang, Jing-Yu; Shen, Hong-Bin

    2015-01-01

    Disulfide connectivity is an important protein structural characteristic. Accurately predicting disulfide connectivity solely from protein sequence helps to improve the intrinsic understanding of protein structure and function, especially in the post-genome era where large volume of sequenced proteins without being functional annotated is quickly accumulated. In this study, a new feature extracted from the predicted protein 3D structural information is proposed and integrated with traditional features to form discriminative features. Based on the extracted features, a random forest regression model is performed to predict protein disulfide connectivity. We compare the proposed method with popular existing predictors by performing both cross-validation and independent validation tests on benchmark datasets. The experimental results demonstrate the superiority of the proposed method over existing predictors. We believe the superiority of the proposed method benefits from both the good discriminative capability of the newly developed features and the powerful modelling capability of the random forest. The web server implementation, called TargetDisulfide, and the benchmark datasets are freely available at: http://csbio.njust.edu.cn/bioinf/TargetDisulfide for academic use.

  5. Distributed Damage Estimation for Prognostics based on Structural Model Decomposition

    Data.gov (United States)

    National Aeronautics and Space Administration — Model-based prognostics approaches capture system knowl- edge in the form of physics-based models of components that include how they fail. These methods consist of...

  6. Multiple Damage Progression Paths in Model-based Prognostics

    Data.gov (United States)

    National Aeronautics and Space Administration — Model-based prognostics approaches employ do- main knowledge about a system, its components, and how they fail through the use of physics-based models. Compo- nent...

  7. An Agent-Based Monetary Production Simulation Model

    DEFF Research Database (Denmark)

    Bruun, Charlotte

    2006-01-01

    An Agent-Based Simulation Model Programmed in Objective Borland Pascal. Program and source code is downloadable......An Agent-Based Simulation Model Programmed in Objective Borland Pascal. Program and source code is downloadable...

  8. An Agent-Based Monetary Production Simulation Model

    DEFF Research Database (Denmark)

    Bruun, Charlotte

    2006-01-01

    An Agent-Based Simulation Model Programmed in Objective Borland Pascal. Program and source code is downloadable......An Agent-Based Simulation Model Programmed in Objective Borland Pascal. Program and source code is downloadable...

  9. Integrated Enterprise Modeling Method Based on Workflow Model and Multiviews%Integrated Enterprise Modeling Method Based on Workflow Model and Multiviews

    Institute of Scientific and Technical Information of China (English)

    林慧苹; 范玉顺; 吴澄

    2001-01-01

    Many enterprise modeling methods are proposed to model thebusiness process of enterprises and to implement CIM systems. But difficulties are still encountered when these methods are applied to the CIM system design and implementation. This paper proposes a new integrated enterprise modeling methodology based on the workflow model. The system architecture and the integrated modeling environment are described with a new simulation strategy. The modeling process and the relationship between the workflow model and the views are discussed.

  10. Validating agent based models through virtual worlds.

    Energy Technology Data Exchange (ETDEWEB)

    Lakkaraju, Kiran; Whetzel, Jonathan H.; Lee, Jina; Bier, Asmeret Brooke; Cardona-Rivera, Rogelio E.; Bernstein, Jeremy Ray Rhythm

    2014-01-01

    As the US continues its vigilance against distributed, embedded threats, understanding the political and social structure of these groups becomes paramount for predicting and dis- rupting their attacks. Agent-based models (ABMs) serve as a powerful tool to study these groups. While the popularity of social network tools (e.g., Facebook, Twitter) has provided extensive communication data, there is a lack of ne-grained behavioral data with which to inform and validate existing ABMs. Virtual worlds, in particular massively multiplayer online games (MMOG), where large numbers of people interact within a complex environ- ment for long periods of time provide an alternative source of data. These environments provide a rich social environment where players engage in a variety of activities observed between real-world groups: collaborating and/or competing with other groups, conducting battles for scarce resources, and trading in a market economy. Strategies employed by player groups surprisingly re ect those seen in present-day con icts, where players use diplomacy or espionage as their means for accomplishing their goals. In this project, we propose to address the need for ne-grained behavioral data by acquiring and analyzing game data a commercial MMOG, referred to within this report as Game X. The goals of this research were: (1) devising toolsets for analyzing virtual world data to better inform the rules that govern a social ABM and (2) exploring how virtual worlds could serve as a source of data to validate ABMs established for analogous real-world phenomena. During this research, we studied certain patterns of group behavior to compliment social modeling e orts where a signi cant lack of detailed examples of observed phenomena exists. This report outlines our work examining group behaviors that underly what we have termed the Expression-To-Action (E2A) problem: determining the changes in social contact that lead individuals/groups to engage in a particular behavior

  11. Influência de citocininas na micropropagação de Mentha x gracilis Sole Cytokinin influence on Mentha x gracilis Sole micropropagation

    Directory of Open Access Journals (Sweden)

    T.M.B Garlet

    2011-01-01

    Full Text Available Mentha x gracilis Sole é um híbrido que produz óleos essenciais ricos em monoterpenos. Tendo em vista a propagação clonal desta planta, segmentos nodais provenientes de plantas assépticas, foram cultivados em meio de Murashige e Skoog (MS suplementado com 0; 0,5; 1,0 e 2,0 µM de cinetina, benzilaminopurina (BAP ou thidiazuron (TDZ. Após 30 dias, as plantas foram transferidas para meio MS não suplementado com citocinina. Os melhores resultados foram obtidos em meio suplementado com 2 µM de TDZ, mostrando ser método viável para a produção rápida de grande número de mudas. Após a transferência das plantas para a casa de vegetação, as plantas propagadas com TDZ apresentam maior número de tricomas glandulares.Mentha x gracilis Sole is a hybrid that produces essential oils rich in monoterpenes. Aimed at the clonal propagation of this plant, nodal segments from aseptic plants were cultured in Murashige and Skoog (MSO medium supplemented with 0; 0.5; 1.0 and 2.0 µM kinetin, benzyl adenine (BAP or thidiazuron (TDZ. After 30 days, plants were transferred to MOS medium without cytokinin supplementation. The best results were obtained in medium supplemented with 2 µM TDZ, which proved to be a viable method for the rapid production of a large number of seedlings. After transference to the greenhouse, plants propagated with TDZ had a larger number of glandular trichomes.

  12. A model-based evaluation system of enterprise

    Institute of Scientific and Technical Information of China (English)

    Yan Junwei; Ye Yang; Wang Jian

    2005-01-01

    This paper analyses the architecture of enterprise modeling, proposesindicator selection principles and indicator decomposition methods, examines the approaches to the evaluation of enterprise modeling and designs an evaluation model of AHP. Then a model-based evaluation system of enterprise is presented toeffectively evaluate the business model in the framework of enterprise modeling.

  13. Model Mapping Approach Based on Ontology Semantics

    Directory of Open Access Journals (Sweden)

    Jinkui Hou

    2013-09-01

    Full Text Available The mapping relations between different models are the foundation for model transformation in model-driven software development. On the basis of ontology semantics, model mappings between different levels are classified by using structural semantics of modeling languages. The general definition process for mapping relations is explored, and the principles of structure mapping are proposed subsequently. The approach is further illustrated by the mapping relations from class model of object oriented modeling language to the C programming codes. The application research shows that the approach provides a theoretical guidance for the realization of model mapping, and thus can make an effective support to model-driven software development

  14. Does Gender Moderate Factors Associated with Whether Spouses Are the Sole Providers of IADL Care to Their Partners?

    Science.gov (United States)

    Feld, Sheila; Dunkle, Ruth E; Schroepfer, Tracy; Shen, Huei-Wern

    2010-07-01

    We explored whether gender moderated the influence of other factors on solo spousal caregiving. The subsample (N = 452) from the AHEAD study included elderly care recipients (CRs) receiving IADL assistance and their spouses. Logistic regression modeled the likelihood of solo spousal IADL care. Gender moderation was tested by product terms between CRs' gender and measures of partners' health, potential helpers, and sociodemographic characteristics. As numbers of CRs' IADLs and couples' proximate daughters increased, wives less often received care solely from their husbands, but husbands' receipt of care from their wives was unaffected. Age differences between spouses and CRs affected solo spousal caregiving to wives and husbands in opposite ways. Regardless of gender, CRs' number of ADL limitations and spouses with IADL or ADL limitations reduced the likelihood of solo spouse care. Identifying circumstances influencing solo spouse caregiving differently among couples with frail wives and husbands facilitates gender sensitive services.

  15. Framework of Pattern Recognition Model Based on the Cognitive Psychology

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    According to the fundamental theory of visual cognition mechanism and cognitive psychology,the visual pattern recognition model is introduced briefly.Three pattern recognition models,i.e.template-based matching model,prototype-based matching model and feature-based matching model are built and discussed separately.In addition,the influence of object background information and visual focus point to the result of pattern recognition is also discussed with the example of recognition for fuzzy letters and figures.

  16. Embedding task-based neural models into a connectome-based model of the cerebral cortex

    Directory of Open Access Journals (Sweden)

    Antonio Ulloa

    2016-08-01

    Full Text Available A number of recent efforts have used large-scale, biologically realistic, neural models to help understand the neural basis for the patterns of activity observed in both resting state and task-related functional neural imaging data. An example of the former is The Virtual Brain (TVB software platform, which allows one to apply large-scale neural modeling in a whole brain framework. TVB provides a set of structural connectomes of the human cerebral cortex, a collection of neural processing units for each connectome node, and various forward models that can convert simulated neural activity into a variety of functional brain imaging signals. In this paper, we demonstrate how to embed a previously or newly constructed task-based large-scale neural model into the TVB platform. We tested our method on a previously constructed large-scale neural model (LSNM of visual object processing that consisted of interconnected neural populations that represent, primary and secondary visual, inferotemporal , and prefrontal cortex. Some neural elements in the original model were 'non task-specific' (NS neurons that served as noise generators to 'task-specific' neurons that processed shapes during a delayed match-to-sample (DMS task. We replaced the NS neurons with an anatomical TVB connectome model of the cerebral cortex comprising 998 regions of interest interconnected by white matter fiber tract weights. We embedded our LSNM of visual object processing into corresponding nodes within the TVB connectome. Reciprocal connections between TVB nodes and our task-based modules were included in this framework. We ran visual object processing simulations and showed that the TVB simulator successfully replaced the noise generation originally provided by NS neurons; i.e., the DMS tasks performed with the hybrid LSNM/TVB simulator generated equivalent neural and fMRI activity to that of the original task-based models. Additionally, we found partial agreement between the

  17. Development of 57 Novel Polymorphic Microsatellite Markers in Half-Smooth Tongue Sole (Cynoglossus semilaevis)

    Institute of Scientific and Technical Information of China (English)

    MIAO Guidong; XU Ying; WANG Di; CHEN Songlin; FAN Tingjun; TIAN Yongsheng

    2011-01-01

    Half-smooth tongue sole (Cynoglossus semilaevis) is a promising species for aquaculture in China.The wild population of C.semilaevis is under threat from environmental factors.Microsatellite markers are very suitable for assessing genetic diversity.Four microsatellite-enriched libraries of half smooth tongue sole (Cynoglossus semilaevis) were constructed,from which 57 polymorphic microsatellites were isolated and characterized.The polymorphism of these microsatellites was assessed by genotyping in 30 individual fish.The number of alleles ranged from 2 to 11,with an average of 4.614 alleles per locus.The values of observed and expected heterozygosities ranged from 0.1000 to 1.0000 and from 0.0966 to 0.8847 respectively.Polymorphism information content (PIC) ranged from 0.0905 to 0.862.These markers would be useful for population structure assessment,genetic linkage map construction and parentage analysis for this species.

  18. A rare case of dumb-bell lipoma of the sole.

    Science.gov (United States)

    Satish, Chetan

    2011-12-01

    A rare case of dumb-bell shaped lipoma of sole of foot in a middle aged lady which had crippled her life for almost a decade in-spite of multiple surgeries. She was initially misdiagnosed to have a corn on her sole and had undergone 3 surgeries spanning about 5 years. Due to the big size of the soft tissue swelling an MRI was done which showed a dumb-bell shaped swelling of foot. A major portion of swelling was lying deep to the plantar fascia after breaching the fascia. She underwent an excision of the swelling and is free of any recurrence after 2 years. She is now able to walk with a normal gait.

  19. Feed intake as explanation for density related growth differences of common sole Solea solea

    DEFF Research Database (Denmark)

    Lund, Ivar; Steenfeldt, Svend Jørgen; Herrmann, Bent

    2013-01-01

    correlated to both fish size and individual SGR. Feed conversion ratio was likewise positively correlated to feed intake. The relative feed intake (g feed g fish−1) was not correlated to fish size at any density tested, but was significantly highest for the LD population. This explains a substantial part......Growth of common sole Solea solea is negatively correlated to density, which affects productivity in culture and hence commercial success. Studies of individual feed intake were performed to examine growth and population dynamics at different densities. Three initial stocking densities: 1.0, 2.......1 and 3.9 kg m−2 of individually tagged sole, referred to as low density (LD), medium density and high density HD), were examined during 145 days. Despite that tank productivity (g m−2 day−1), was highest for the HD group, the specific growth rate (SGR) decreased significantly with increase in stocking...

  20. Nitrate Removal from Drinking Water with Sodium Citrate as Sole Carbon Source

    Institute of Scientific and Technical Information of China (English)

    YAN Bo; ZHAO Lin; TAN Xin

    2005-01-01

    This paper investigates the effect of using sodium citrate(NaC6H5O6*2H2O)as sole carbon source for nitrate removal from drinking water.With sodium citrate as sole carbon source, batch experiments have been conducted to study the law of denitrification influenced by pH, C/N and temperature. Results show that a denitrification rate reaching 1.32 g NO-3-N /(g Biomass*d) was obtained when pH was at 7.5,C/N at 1.7(atom ratio), and temperature from 20 ℃ to 30 ℃. The results also show that denitrification rate with sodium citrate as carbon source approaches to that with methanol as carbon source.

  1. Hypnosis as sole anaesthesia for skin tumour removal in a patient with multiple chemical sensitivity.

    Science.gov (United States)

    Facco, E; Pasquali, S; Zanette, G; Casiglia, E

    2013-09-01

    A female patient with multiple chemical sensitivity and previous anaphylactoid reactions to local anaesthetics was admitted for removal of a thigh skin tumour under hypnosis as sole anaesthesia. The hypnotic protocol included hypnotic focused analgesia and a pre-operative pain threshold test. After inducing hypnosis, a wide excision was performed, preserving the deep fascia, and the tumour was removed; the patient's heart rate and blood pressure did not increase during the procedure. When the patient was de-hypnotised, she reported no pain and was discharged immediately. Our case confirms the efficacy of hypnosis and demonstrates that it may be valuable as a sole anaesthetic method in selected cases. Hypnosis can prevent pain perception and surgical stress as a whole, comparing well with anaesthetic drugs.

  2. A Software Service Framework Model Based on Agent

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    This paper presents an agent-based software service framework model called ASF, and definesthe basic concepts and structure of ASF model. It also describes the management and process mechanismsin ASF model.

  3. Degradation of o-chloronitrobenzene as the sole carbon and nitrogen sources by Pseudomonas putida OCNB-1

    Institute of Scientific and Technical Information of China (English)

    WU Haizhen; WEI Chaohai; WAMG Yaqin; HE Qincong; LIANG Shizhong

    2009-01-01

    A bacterial strain that utilized o-chloronitrobenzene (o-CNB) as the sole carbon, nitrogen and energy sources was isolated from an activated sludge collected from an industrial waste treatment plant. It was identified as Pseudomonas putida based on its morphology, physiological, and biochemical characteristics with an automatic biometrical system and the 16S rRNA sequence analysis. Microcosm study showed that the biodegradation of o-CNB was optimized at culture medium pH 8.0 and temperature of 32℃. At these conditions, the strain degraded 85% of o-CNB at a starting concentration of 1.1 mmol/L in 42 h. o-Chloroaniline was identified as the major metabolite with both high performance liquid chromatography (HPLC) and gas chromatography-mass spectrometry (GC-MS). The study showed that o-chloronitrobenzene degradation by Pseudomonas putida OCNB-1 was initiated by aniline dioxyenase, nitrobenzene reductase and catechol-1,2-dioxygenase.

  4. Partial duplication 2p as the sole abnormality in two cases with anencephaly.

    Science.gov (United States)

    Thangavelu, Maya; Frolich, Gary; Rogers, David

    2004-01-15

    Anencephaly/NTD has been observed in aneuploid and non-aneuploid individuals. We present two cases of anencephaly diagnosed prenatally with partial duplication of the short arm of chromosome 2 as the sole abnormality. The absence of aneuploidy involving other regions of the genome in these cases, further substantiates suggestions of the existence of a gene or genes on the short arm of chromosome 2 critical in the development of the central nervous system.

  5. Single Locus Maintains Large Variation of Sex Reversal in Half-Smooth Tongue Sole (Cynoglossus semilaevis)

    OpenAIRE

    Li Jiang; Hengde Li

    2016-01-01

    Sex determination is a fundamental biological process for individual sex development and population sex ratios. However, for some species, the primary sex might be altered during development, and individuals can develop into the opposite sex. Sex reversal may happen in insects, reptiles, amphibians, and fishes. In half-smooth tongue sole (Cynoglossus semilaevis), some genetically female fish irreversibly reverse to pseudomales, resulting in higher costs in aquaculture owing to a lower growth ...

  6. Chemokines Responses to Ascaris Lumbricoides Sole Infection and Co-infection with Hookworm among Nigerians

    OpenAIRE

    Omorodion Oriri Asemota; O.P.G. Nmorsi; Isaac, C.; E M Odoya; Akinseye, J; Isaac, O

    2014-01-01

    Background: Geohelminth infections are predominant in Nigeria and communities at greatest risks are those with poor environmental/sanitary conditions and unhygienic habits. Chemokine ligands (CXCL) a class under chemokine group play important roles in the immune system by either mediating susceptible or protective immune responses to parasitic infections. Aim: This study was to assess the impact of Ascaris lumbricoides sole infection and co-infection on some serum chemokines (CXCL5, CXCL9, an...

  7. Mechanical stimulation of the foot sole in a supine position for ground reaction force simulation

    OpenAIRE

    2014-01-01

    Background:\\ud To promote early rehabilitation of walking, gait training can start even when patients are on bed rest. Supine stepping in the early phase after injury is proposed to maximise the beneficial effects of gait restoration. In this training paradigm, mechanical loading on the sole of the foot is required to mimic the ground reaction forces that occur during overground walking. A pneumatic shoe platform was developed to produce adjustable forces on the heel and the forefoot with an ...

  8. An overview of the understanding of ions containing solely fluorine atoms.

    Science.gov (United States)

    Ponikvar-Svet, Maja; Edwards, Kathleen F; Liebman, Joel F

    2013-01-01

    We discuss in the current paper ions containing solely fluorine atoms, F-, F2- and F3-, their corresponding cationic and/or multiply charged counterparts. While the emphasis of the paper is on gas phase species, their energetics and reactions, aqueous solutions are also discussed. In particular, biomedical and analytical aspects of F- are also considered. The new trichotomy of convenience, anthropocentrism and folksonomy is also applied to the understanding of our fluorine-containing ions.

  9. Self-Oscillating Resonant Gate Drive for Resonant Inverters and Rectifiers Composed Solely of Passive Components

    DEFF Research Database (Denmark)

    Madsen, Mickey Pierre; Pedersen, Jeppe Arnsdorf; Knott, Arnold;

    2014-01-01

    This paper presents a new self-oscillating resonant gate drive composed solely of passive components. The gate drive can be used in various resonant converters and inverters and can be used for both low and high side gate drive. The paper presents examples of how higher order harmonics can be use...... Frequency (VHF) range, all showing good results with peak efficiency up to 82% and output regulation from 70% to full load without bursting....

  10. Acute myelopathy with sudden paraplegia as the sole manifestation of meningococcal meningitis

    Directory of Open Access Journals (Sweden)

    Wanis H. Ibrahim

    2010-02-01

    Full Text Available Acute myelopathy with sudden paraplegia is a very rare manifestation of meningococcal meningitis, with only a few cases reported in the literature. In almost all previously reported cases, other clinical manifestations of meningitis, such as fever, headache, and neck stiffness preceded acute myelopathy. In this paper, we report a case of acute myelopathy with sudden paraplegia as the sole manifestation of meningococcal meningitis, in the absence of other clinical manifestations of meningitis.

  11. Dynamic Metabolic Model Building Based on the Ensemble Modeling Approach

    Energy Technology Data Exchange (ETDEWEB)

    Liao, James C. [Univ. of California, Los Angeles, CA (United States)

    2016-10-01

    Ensemble modeling of kinetic systems addresses the challenges of kinetic model construction, with respect to parameter value selection, and still allows for the rich insights possible from kinetic models. This project aimed to show that constructing, implementing, and analyzing such models is a useful tool for the metabolic engineering toolkit, and that they can result in actionable insights from models. Key concepts are developed and deliverable publications and results are presented.

  12. A Hubble diagram from Type II Supernovae based solely on photometry: the Photometric-Colour Method

    CERN Document Server

    T., de Jaeger; P., Anderson J; L., Galbany; M., Hamuy; M., Phillips M; M., Stritzinger; C., Gutiérrez; L., Bolt; R., Burns C; A., Campillay; S., Castellón; C., Contreras; G., Folatelli; L., Freedman W; Y., Hsiao E; K., Krisciunas; W., Krzeminski; H., Kuncarayakti; N., Morrell; F., Olivares E; E., Persson S; N, Suntzeff

    2015-01-01

    We present a Hubble diagram of type II supernovae using corrected magnitudes derived only from photometry, with no input of spectral information. We use a data set from the Carnegie Supernovae Project I (CSP) for which optical and near-infrared light-curves were obtained. The apparent magnitude is corrected by two observables, one corresponding to the slope of the plateau in the $V$ band and the second a colour term. We obtain a dispersion of 0.44 mag using a combination of the $(V-i)$ colour and the $r$ band and we are able to reduce the dispersion to 0.39 mag using our golden sample. A comparison of our photometric colour method (PCM) with the standardised candle method (SCM) is also performed. The dispersion obtained for the SCM (which uses both photometric and spectroscopic information) is 0.29 mag which compares with 0.43 mag from the PCM, for the same SN sample. The construction of a photometric Hubble diagram is of high importance in the coming era of large photometric wide-field surveys, which will in...

  13. Prototype of haptic device for sole of foot using magnetic field sensitive elastomer

    Science.gov (United States)

    Kikuchi, T.; Masuda, Y.; Sugiyama, M.; Mitsumata, T.; Ohori, S.

    2013-02-01

    Walking is one of the most popular activities and a healthy aerobic exercise for the elderly. However, if they have physical and / or cognitive disabilities, sometimes it is challenging to go somewhere they don't know well. The final goal of this study is to develop a virtual reality walking system that allows users to walk in virtual worlds fabricated with computer graphics. We focus on a haptic device that can perform various plantar pressures on users' soles of feet as an additional sense in the virtual reality walking. In this study, we discuss a use of a magnetic field sensitive elastomer (MSE) as a working material for the haptic interface on the sole. The first prototype with MSE was developed and evaluated in this work. According to the measurement of planter pressures, it was found that this device can perform different pressures on the sole of a light-weight user by applying magnetic field on the MSE. The result also implied necessities of the improvement of the magnetic circuit and the basic structure of the mechanism of the device.

  14. Craniofacial pain can be the sole prodromal symptom of an acute myocardial infarction: an interdisciplinary study.

    Science.gov (United States)

    Kreiner, Marcelo; Álvarez, Ramón; Michelis, Virginia; Waldenström, Anders; Isberg, Annika

    2016-04-01

    We recently found craniofacial pain to be the sole symptom of an acute myocardial infarction (AMI) in 4% of patients. We hypothesized that this scenario is also true for symptoms of prodromal (pre-infarction) angina. We studied 326 consecutive patients who experienced myocardial ischemia. Intra-individual variability analyses with respect to ECG findings and pain characteristics were performed for those 150 patients who experienced at least one recurrent ischemic episode. AMI patients (n=113) were categorized into two subgroups: "abrupt onset" (n=81) and "prodromal angina" (n=32). Age, gender and risk factor comparisons were performed between groups. Craniofacial pain constituted the sole prodromal symptom of an AMI in 5% of patients. In those who experienced two ischemic episodes, women were more likely than men to experience craniofacial pain in both episodes (ppain quality descriptors "pressure" and "burning". This study is to our knowledge the first to report that craniofacial pain can be the only symptom of a pre-infarction angina. Craniofacial pain constitutes the sole prodromal AMI symptom in one out of 20 AMI patients. Recognition of this atypical symptom presentation is low because research on prodromal AMI symptoms has to date studied only patients with chest pain. To avoid a potentially fatal misdiagnosis, awareness of this clinical presentation needs to be brought to the attention of clinicians, researchers and the general public.

  15. Rhythm Pattern of Sole through Electrification of the Human Body When Walking

    Science.gov (United States)

    Takiguchi, Kiyoaki; Wada, Takayuki; Tohyama, Shigeki

    The rhythm of automatic cyclic movements such as walking is known to be generated by a rhythm generator called CPG in the spinal cord. The measurement of rhythm characteristics in walking is considered to be important for analyzing human bipedal walking and adaptive walking on irregular terrain. In particular, the soles that contact the terrain surface perform flexible movements similar to the movement of the fins of a lungfish, which is considered to be the predecessor of land animals. The sole movements are believed to be a basic movement acquired during prehistoric times. The detailed rhythm pattern of sole motion is considered to be important. We developed a method for measuring electrification without installing device on a subject's body and footwear for stabilizing the electrification of the human body. We measured the rhythm pattern of 20 subjects including 4 infants when walking by using this system and the corresponding equipment. Therefore, we confirmed the commonality of the correlative rhythm patterns of 20 subjects. Further, with regard to an individual subject, the reproducibility of a rhythm pattern with strong correlation coefficient > 0.93 ± 0.5 (mean ± SD) concerning rhythms of trials that are differently conducted on adult subjects could be confirmed.

  16. Daily feeding and protein metabolism rhythms in Senegalese sole post-larvae

    Science.gov (United States)

    Yúfera, Manuel; Engrola, Sofia

    2017-01-01

    ABSTRACT Fish hatcheries must adapt larval feeding protocols to feeding behavior and metabolism patterns to obtain more efficient feed utilization. Fish larvae exhibit daily ingesting rhythms rather than ingesting food continuously throughout the day. The aim of this study was to determine the daily patterns of feed intake, protein digestibility, protein retention and catabolism in Senegalese sole post-larvae (Solea senegalensis; 33 days post-hatching) using 14C-labeled Artemia protein and incubation in metabolic chambers. Sole post-larvae were fed at 09:00, 15:00, 21:00, 03:00 and 09:00+1 day; and those fed at 09:00, 21:00, 03:00 and 09:00+1 day showed significantly higher feed intake than post-larvae fed at 15:00 h (P=0.000). Digestibility and evacuation rate of ingested protein did not change during the whole cycle (P=0.114); however, post-larvae fed at 21:00 and 03:00 h showed the significantly highest protein retention efficiency and lowest catabolism (P=0.002). Therefore, results confirm the existence of daily rhythmicity in feeding activity and in the utilization of the ingested nutrients in Senegalese sole post-larvae. PMID:27895049

  17. Measurement-based load modeling: Theory and application

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Load model is one of the most important elements in power system operation and control. However, owing to its complexity, load modeling is still an open and very difficult problem. Summarizing our work on measurement-based load modeling in China for more than twenty years, this paper systematically introduces the mathematical theory and applications regarding the load modeling. The flow chart and algorithms for measurement-based load modeling are presented. A composite load model structure with 13 parameters is also proposed. Analysis results based on the trajectory sensitivity theory indicate the importance of the load model parameters for the identification. Case studies show the accuracy of the presented measurement-based load model. The load model thus built has been validated by field measurements all over China. Future working directions on measurement- based load modeling are also discussed in the paper.

  18. MRO CTX-based Digital Terrain Models

    Science.gov (United States)

    Dumke, Alexander

    2016-04-01

    In planetary surface sciences, digital terrain models (DTM) are paramount when it comes to understanding and quantifying processes. In this contribution an approach for the derivation of digital terrain models from stereo images of the NASA Mars Reconnaissance Orbiter (MRO) Context Camera (CTX) are described. CTX consists of a 350 mm focal length telescope and 5000 CCD sensor elements and is operated as pushbroom camera. It acquires images with ~6 m/px over a swath width of ~30 km of the Mars surface [1]. Today, several approaches for the derivation of CTX DTMs exist [e. g. 2, 3, 4]. The discussed approach here is based on established software and combines them with proprietary software as described below. The main processing task for the derivation of CTX stereo DTMs is based on six steps: (1) First, CTX images are radiometrically corrected using the ISIS software package [5]. (2) For selected CTX stereo images, exterior orientation data from reconstructed NAIF SPICE data are extracted [6]. (3) In the next step High Resolution Stereo Camera (HRSC) DTMs [7, 8, 9] are used for the rectification of CTX stereo images to reduce the search area during the image matching. Here, HRSC DTMs are used due to their higher spatial resolution when compared to MOLA DTMs. (4) The determination of coordinates of homologous points between stereo images, i.e. the stereo image matching process, consists of two steps: first, a cross-correlation to obtain approximate values and secondly, their use in a least-square matching (LSM) process in order to obtain subpixel positions. (5) The stereo matching results are then used to generate object points from forward ray intersections. (6) As a last step, the DTM-raster generation is performed using software developed at the German Aerospace Center, Berlin. Whereby only object points are used that have a smaller error than a threshold value. References: [1] Malin, M. C. et al., 2007, JGR 112, doi:10.1029/2006JE002808 [2] Broxton, M. J. et al

  19. The Community-based Whole Magnetosphere Model

    Science.gov (United States)

    2011-11-15

    Tribulations and Exultations in Coupling Models of the Magnetosphere with Ionosphere-Thermosphere Models, Plane- tary Aeronomy ISSI Meeting, Bern...Exultations in Coupling Models of the Magnetosphere CWMM-19 Ridley CWMM Final Report with Ionosphere-Thermosphere Models, Plane- tary Aeronomy ISSI

  20. Probabilistic Based Modeling and Simulation Assessment

    Science.gov (United States)

    2010-06-01

    but with the head and neck replaced with a high fidelity cervical spine and head model. The occupant models were used to determine the effects of...fidelity cervical spine and head model... vertebrae , including the disks, ligaments and musculature, Figure 6. In total there are 57837 elements with 63713 nodes. A full description of the model

  1. A stability condition for turbulence model: From EMMS model to EMMS-based turbulence model

    CERN Document Server

    Zhang, Lin; Wang, Limin; Li, Jinghai

    2013-01-01

    The closure problem of turbulence is still a challenging issue in turbulence modeling. In this work, a stability condition is used to close turbulence. Specifically, we regard single-phase flow as a mixture of turbulent and non-turbulent fluids, separating the structure of turbulence. Subsequently, according to the picture of the turbulent eddy cascade, the energy contained in turbulent flow is decomposed into different parts and then quantified. A turbulence stability condition, similar to the principle of the energy-minimization multi-scale (EMMS) model for gas-solid systems, is formulated to close the dynamic constraint equations of turbulence, allowing the heterogeneous structural parameters of turbulence to be optimized. We call this model the `EMMS-based turbulence model', and use it to construct the corresponding turbulent viscosity coefficient. To validate the EMMS-based turbulence model, it is used to simulate two classical benchmark problems, lid-driven cavity flow and turbulent flow with forced con...

  2. A Bit Progress on Word—Based Language Model

    Institute of Scientific and Technical Information of China (English)

    陈勇; 陈国评

    2003-01-01

    A good language model is essential to a postprocessing algorithm for recognition systems. In the past, researchers have pre-sented various language models, such as character based language models, word based language model, syntactical rules :language mod-el, hybrid models, etc. The word N-gram model is by far an effective and efficient model, but one has to address the problem of data sparseness in establishing the model. Katz and Kneser et al. respectively presented effective remedies to solve this challenging prob-lem. In this study, we proposed an improvement to their methods by incorporating Chinese language-specific information or Chinese word class information into the system.

  3. Study of chaos based on a hierarchical model

    Energy Technology Data Exchange (ETDEWEB)

    Yagi, Masatoshi; Itoh, Sanae-I. [Kyushu Univ., Fukuoka (Japan). Research Inst. for Applied Mechanics

    2001-12-01

    Study of chaos based on a hierarchical model is briefly reviewed. Here we categorize hierarchical model equations, i.e., (1) a model with a few degrees of freedom, e.g., the Lorenz model, (2) a model with intermediate degrees of freedom like a shell model, and (3) a model with many degrees of freedom such as a Navier-Stokes equation. We discuss the nature of chaos and turbulence described by these models via Lyapunov exponents. The interpretation of results observed in fundamental plasma experiments is also shown based on a shell model. (author)

  4. Genotoxic and enzymatic effects of fluoranthene in microsomes and freshly isolated hepatocytes from sole (Solea solea).

    Science.gov (United States)

    Wessel, N; Ménard, D; Pichavant-Rafini, K; Ollivier, H; Le Goff, J; Burgeot, T; Akcha, F

    2012-02-01

    The fluoranthene (Fluo) is one of the most abundant polycyclic aromatic hydrocarbons (PAHs) in human food and in marine compartments. However, the existing data on its genotoxicity is poor and controversial. The aim of this study was to assess in vitro the potential genotoxicity of Fluo in sole and its possible effect on CYP450 modulation. Freshly isolated hepatocytes were exposed for 24 h to a range of Fluo concentrations from 0.5 to 50 μM in both culture flasks and microplate wells. The ethoxyresorufin-O-deethylase (EROD) activity was measured as an indicator of the activity of the cytochrome P450 1A1 (CYP1A1). The genotoxic effects were evaluated by measuring both DNA strand breaks and DNA adducts by the alkaline comet assay and the postlabeling technique respectively. Calf thymus DNA was also exposed to Fluo in the presence of sole liver microsomes in order to check for Fluo DNA adduct formation. In sole hepatocytes, Fluo was shown to induce a decrease in the EROD activity in a concentration-dependent manner. A significant genotoxic effect was observed in terms of DNA strand breakage from an exposure concentration of 5 μM: despite a concentration-dependent effect was observed, it did not follow a linear dose-response. The response was similar whatever the way of exposure in flasks or in wells. One reproducible adduct was detected in the hepatocytes exposed to the highest concentrations of Fluo. The formation of Fluo adducts was confirmed by the detection of one reproducible adduct following in vitro exposure of calf thymus DNA to 100 and 200 μM of Fluo in the presence of sole microsomes. These results demonstrate the potential of sole hepatocytes to metabolize Fluo in 24 h into reactive species, able to induce genotoxicity by DNA strand breakage and DNA adduct formation. Moreover, a miniaturized cell exposure system was validated for further experiments using fewer amounts of hepatocytes and contaminants, and allowing exposure to PAH metabolites. Copyright

  5. Recommendation based on trust diffusion model.

    Science.gov (United States)

    Yuan, Jinfeng; Li, Li

    2014-01-01

    Recommender system is emerging as a powerful and popular tool for online information relevant to a given user. The traditional recommendation system suffers from the cold start problem and the data sparsity problem. Many methods have been proposed to solve these problems, but few can achieve satisfactory efficiency. In this paper, we present a method which combines the trust diffusion (DiffTrust) algorithm and the probabilistic matrix factorization (PMF). DiffTrust is first used to study the possible diffusions of trust between various users. It is able to make use of the implicit relationship of the trust network, thus alleviating the data sparsity problem. The probabilistic matrix factorization (PMF) is then employed to combine the users' tastes with their trusted friends' interests. We evaluate the algorithm on Flixster, Moviedata, and Epinions datasets, respectively. The experimental results show that the recommendation based on our proposed DiffTrust + PMF model achieves high performance in terms of the root mean square error (RMSE), Recall, and F Measure.

  6. Discovering Diabetes Complications: an Ontology Based Model

    Science.gov (United States)

    Daghistani, Tahani; Shammari, Riyad Al; Razzak, Muhammad Imran

    2015-01-01

    Background: Diabetes is a serious disease that spread in the world dramatically. The diabetes patient has an average of risk to experience complications. Take advantage of recorded information to build ontology as information technology solution will help to predict patients who have average of risk level with certain complication. It is helpful to search and present patient’s history regarding different risk factors. Discovering diabetes complications could be useful to prevent or delay the complications. Method: We designed ontology based model, using adult diabetes patients’ data, to discover the rules of diabetes with its complications in disease to disease relationship. Result: Various rules between different risk factors of diabetes Patients and certain complications generated. Furthermore, new complications (diseases) might be discovered as new finding of this study, discovering diabetes complications could be useful to prevent or delay the complications. Conclusion: The system can identify the patients who are suffering from certain risk factors such as high body mass index (obesity) and starting controlling and maintaining plan. PMID:26862251

  7. GENETIC-BASED NUTRITION RECOMMENDATION MODEL

    Directory of Open Access Journals (Sweden)

    S. A.A. Fayoumi

    2014-01-01

    Full Text Available Evolutionary computing is the collective name for a range of problem-solving techniques based on principles of biological evolution, such as natural selection and genetic inheritance. These techniques are being widely applied to a variety of problems in many vital fields. Also, Evolutionary Algorithms (EA which applied the principles of Evolutionary computations, such as genetic algorithm, particle swarm, ant colony and bees algorithm and so on play an important role in decision making process. EAs serve a lot of fields which can affect our life directly, such as medicine, engineering, transportations, communications. One of these vital fields is Nutrition which can be viewed from several points of view as medical, physical, social, environmental and psychological point of view. This study, presents a proposed model that shows how evolutionary computing generally and genetic algorithm specifically-as a powerful algorithm of evolutionary algorithms-can be used to recommend an appropriate nutrition style in a medical and physical sides only to each person according to his/her personal and medical measurements.

  8. Model Based Analysis and Test Generation for Flight Software

    Science.gov (United States)

    Pasareanu, Corina S.; Schumann, Johann M.; Mehlitz, Peter C.; Lowry, Mike R.; Karsai, Gabor; Nine, Harmon; Neema, Sandeep

    2009-01-01

    We describe a framework for model-based analysis and test case generation in the context of a heterogeneous model-based development paradigm that uses and combines Math- Works and UML 2.0 models and the associated code generation tools. This paradigm poses novel challenges to analysis and test case generation that, to the best of our knowledge, have not been addressed before. The framework is based on a common intermediate representation for different modeling formalisms and leverages and extends model checking and symbolic execution tools for model analysis and test case generation, respectively. We discuss the application of our framework to software models for a NASA flight mission.

  9. Modeling dark fermentation for biohydrogen production: ADM1-based model vs. Gompertz model

    Energy Technology Data Exchange (ETDEWEB)

    Gadhamshetty, Venkataramana [Air Force Research Laboratory, Tyndall AFB, 139 Barnes Drive, Panama City, FL 32403 (United States); Arudchelvam, Yalini; Nirmalakhandan, Nagamany [Civil Engineering Department, New Mexico State University, Las Cruces, NM 88003 (United States); Johnson, David C. [Institute for Energy and Environment, New Mexico State University, Las Cruces, NM 88003 (United States)

    2010-01-15

    Biohydrogen production by dark fermentation in batch reactors was modeled using the Gompertz equation and a model based on Anaerobic Digestion Model (ADM1). The ADM1 framework, which has been well accepted for modeling methane production by anaerobic digestion, was modified in this study for modeling hydrogen production. Experimental hydrogen production data from eight reactor configurations varying in pressure conditions, temperature, type and concentration of substrate, inocula source, and stirring conditions were used to evaluate the predictive abilities of the two modeling approaches. Although the quality of fit between the measured and fitted hydrogen evolution by the Gompertz equation was high in all the eight reactor configurations with r{sup 2} {proportional_to}0.98, each configuration required a different set of model parameters, negating its utility as a general approach to predict hydrogen evolution. On the other hand, the ADM1-based model (ADM1BM) with predefined parameters was able to predict COD, cumulative hydrogen production, as well as volatile fatty acids production, albeit at a slightly lower quality of fit. Agreement between the experimental temporal hydrogen evolution data and the ADM1BM predictions was statistically significant with r{sup 2} > 0.91 and p-value <1E-04. Sensitivity analysis of the validated model revealed that hydrogen production was sensitive to only six parameters in the ADM1BM. (author)

  10. Research on the Integration of Bionic Geometry Modeling and Simulation of Robot Foot Based on Characteristic Curve

    Science.gov (United States)

    He, G.; Zhu, H.; Xu, J.; Gao, K.; Zhu, D.

    2017-09-01

    The bionic research of shape is an important aspect of the research on bionic robot, and its implementation cannot be separated from the shape modeling and numerical simulation of the bionic object, which is tedious and time-consuming. In order to improve the efficiency of shape bionic design, the feet of animals living in soft soil and swamp environment are taken as bionic objects, and characteristic skeleton curve, section curve, joint rotation variable, position and other parameters are used to describe the shape and position information of bionic object’s sole, toes and flipper. The geometry modeling of the bionic object is established by using the parameterization of characteristic curves and variables. Based on this, the integration framework of parametric modeling and finite element modeling, dynamic analysis and post-processing of sinking process in soil is proposed in this paper. The examples of bionic ostrich foot and bionic duck foot are also given. The parametric modeling and integration technique can achieve rapid improved design based on bionic object, and it can also greatly improve the efficiency and quality of robot foot bionic design, and has important practical significance to improve the level of bionic design of robot foot’s shape and structure.

  11. Computer Profiling Based Model for Investigation

    Directory of Open Access Journals (Sweden)

    Neeraj Choudhary

    2011-10-01

    Full Text Available Computer profiling is used for computer forensic analysis, and proposes and elaborates on a novel model for use in computer profiling, the computer profiling object model. The computer profiling object model is an information model which models a computer as objects with various attributes and inter-relationships. These together provide the information necessary for a human investigator or an automated reasoning engine to make judgments as to the probable usage and evidentiary value of a computer system. The computer profiling object model can be implemented so as to support automated analysis to provide an investigator with the informationneeded to decide whether manual analysis is required.

  12. 49 CFR 1242.68 - Freight lost or damaged-solely related (to yard) (account 51-52-00).

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Freight lost or damaged-solely related (to yard) (account 51-52-00). 1242.68 Section 1242.68 Transportation Other Regulations Relating to Transportation... RAILROADS 1 Operating Expenses-Transportation § 1242.68 Freight lost or damaged—solely related (to...

  13. Thermal Preference of Juvenile Dover Sole (Solea solea) in Relation to Thermal Acclimation and Optimal Growth Temperature

    NARCIS (Netherlands)

    Schram, E.; Bierman, S.M.; Teal, L.R.; Vis, van de H.; Rijnsdorp, A.D.

    2013-01-01

    Dover sole (Solea solea) is an obligate ectotherm with a natural thermal habitat ranging from approximately 5 to 27°C. Thermal optima for growth lie in the range of 20 to 25°C. More precise information on thermal optima for growth is needed for cost-effective Dover sole aquaculture. The main objecti

  14. 26 CFR 1.1033(e)-1 - Sale or exchange of livestock solely on account of drought.

    Science.gov (United States)

    2010-04-01

    ... of drought. 1.1033(e)-1 Section 1.1033(e)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF... Sale or exchange of livestock solely on account of drought. (a) The sale or exchange of livestock... if the sale or exchange of such livestock by the taxpayer is solely on account of drought....

  15. Research of database-based modeling for mining management system

    Institute of Scientific and Technical Information of China (English)

    WU Hai-feng; JIN Zhi-xin; BAI Xi-jun

    2005-01-01

    Put forward the method to construct the simulation model automatically with database-based automatic modeling(DBAM) for mining system. Designed the standard simulation model linked with some open cut Pautomobile dispatch system. Analyzed and finded out the law among them, and designed model maker to realize the automatic programming of the new model program.

  16. Definition of Model-based diagnosis problems with Altarica

    OpenAIRE

    Pencolé, Yannick; Chanthery, Elodie; Peynot, Thierry

    2016-01-01

    International audience; This paper presents a framework for modeling diagnosis problems based on a formal language called Altarica. The initial purpose of the language Altarica was to define a modeling language for safety analysis. This language has been developed as a collaboration between academics and industrial partners and is used in some industrial companies. The paper shows that the expres-sivity of this language, mixing event-based and state-based models, is sufficient to model classi...

  17. Modeling and simulation of complex systems a framework for efficient agent-based modeling and simulation

    CERN Document Server

    Siegfried, Robert

    2014-01-01

    Robert Siegfried presents a framework for efficient agent-based modeling and simulation of complex systems. He compares different approaches for describing structure and dynamics of agent-based models in detail. Based on this evaluation the author introduces the "General Reference Model for Agent-based Modeling and Simulation" (GRAMS). Furthermore he presents parallel and distributed simulation approaches for execution of agent-based models -from small scale to very large scale. The author shows how agent-based models may be executed by different simulation engines that utilize underlying hard

  18. Model based sustainable production of biomethane

    OpenAIRE

    Biernacki, Piotr

    2014-01-01

    The main intention of this dissertation was to evaluate sustainable production of biomethane with use of mathematical modelling. To achieve this goal, widely acknowledged models like Anaerobic Digestion Model No.1 (ADM1), describing anaerobic digestion, and electrolyte Non-Random Two Liquid Model (eNRTL), for gas purification, were utilized. The experimental results, batch anaerobic digestion of different substrates and carbon dioxide solubility in 2-(Ethylamino)ethanol, were used to determin...

  19. Biodegradation and utilization of 4-n-nonylphenol by Aspergillus versicolor as a sole carbon and energy source

    Energy Technology Data Exchange (ETDEWEB)

    Krupiński, Mariusz; Janicki, Tomasz [Department of Industrial Microbiology and Biotechnology, University of Lodz, Banacha 12/16, 90-237 Łódź (Poland); Pałecz, Bartłomiej [Department of Physical Chemistry, University of Lodz, Pomorska 165, 90-236 Łódź (Poland); Długoński, Jerzy, E-mail: jdlugo@biol.uni.lodz.pl [Department of Industrial Microbiology and Biotechnology, University of Lodz, Banacha 12/16, 90-237 Łódź (Poland)

    2014-09-15

    Highlights: • A. versicolor is able to degrade 4-n-NP as the sole source of carbon and energy. • 4-n-NP removal by A. versicolor was accompanied by the formation of metabolites. • Radioactive experiments show complete 4-n-NP mineralization by A. versicolor. • 4-n-NP initiates heat production in the A. versicolor spores. - Abstract: 4-n-Nonylphenol (4-n-NP) is an environmental pollutant with endocrine-disrupting activities that is formed during the degradation of nonylphenol polyethoxylates, which are widely used as surfactants. Utilization of 4-n-NP by the filamentous fungus Aspergillus versicolor as the sole carbon and energy source was investigated. By means of gas chromatography–mass spectrometry, we showed that in the absence of any carbon source other than 4-n-NP in the medium, A. versicolor completely removed the xenobiotic (100 mg L{sup −1}) after 3 d of cultivation. Moreover, mass spectrometric analysis of intracellular extracts led to the identification of eight intermediates. The mineralization of the xenobiotic in cultures supplemented with 4-n-NP [ring-{sup 14}C(U)] as a growth substrate was also assessed. After 3 d of incubation, approximately 50% of the initially applied radioactivity was recovered in the form of {sup 14}CO{sub 2}, proving that this xenobiotic was completely metabolized and utilized by A. versicolor as a carbon source. Based on microscopic analysis, A. versicolor is capable of germinating spores under such conditions. To confirm these observations, a microcalorimetric method was used. The results show that even the highest amount of 4-n-NP initiates heat production in the fungal samples, proving that metabolic processes were affected by the use of 4-n-NP as an energetic substrate.

  20. On Process Modelling Using Physical Oriented And Phenomena Based Principles

    Directory of Open Access Journals (Sweden)

    Mihai Culea

    2000-12-01

    Full Text Available This work presents a modelling framework based on phenomena description of the process. The approach is taken to easy understand and construct process model in heterogeneous possible distributed modelling and simulation environments. A simplified case study of a heat exchanger is considered and Modelica modelling language to check the proposed concept. The partial results are promising and the research effort will be extended in a computer aided modelling environment based on phenomena.

  1. P-T evolution of slivers of garnet-bearing micaschist in the sole of the Western Vardar Ophiolite Unit at Brezovica, Kosovo

    Science.gov (United States)

    Massonne, Hans-Joachim; Koller, Friedrich; Onuzi, Kujtim

    2016-04-01

    at a pressure of 11.5 kbar, which is compatible with the aforementioned talc + phengite assemblage. We think that the recognized HP metamorphism of the studied micaschist was caused by the load of the obducting oceanic lithosphere, which must have been as thick as 35 km. Heating of the overridden rocks during this obduction process resulted in the release of H2O, which hydrated the mantle rocks at the base of the obducting oceanic lithosphere. An alternative model, which assigned the location of the hydration to the mantle wedge overlying a subduction zone, was abandoned also because of the existence of higher levels of oceanic crust, such as pillow lavas, in the preserved oceanic lithosphere close to the Brezovica region.

  2. Rainfall interception by maize canopy: Development and application of a process-based model

    Science.gov (United States)

    Frasson, Renato Prata de Moraes; Krajewski, Witold F.

    2013-05-01

    The interaction between rain drops and crop canopies changes the microphysical characteristics of precipitation. Understanding the mechanisms driving these changes is a key step towards unveiling the mechanics of soil water recharge, soil erosion under crop canopies, and evaporation of intercepted rainfall. The latter caused by, for example, the reduced aerodynamic resistance to evaporation of splashed droplets. We propose a model that uses drop-size and velocity distributions as well as the three-dimensional geometry of the maize canopy to simulate the movement of raindrops on the surface of the leaves. The model accounts for the interception, redirection, retention, coalescence, and re-interception of drops to predict the location, size, and velocity of throughfall drops beneath the canopy. The throughfall results are presented as two-dimensional matrices, in which each term corresponds to the accumulated volume of drops that dripped in that location, which offers insight into its spatial distribution under the foliage. We examine the modification of the drop-size distribution by the maize canopy by recalculating the drop velocity based on their size and detachment height. They built the three-dimensional digital canopy that is employed in the simulation by creating modified copies of one photogrammetry-generated digital model of a plant located inside their experimental site. The canopy model accounts for the projected overlap of the single plant leaves. We evaluate the results against measurements obtained during 10 storms that occurred between 14 July 2009 and 28 August 2009 in Shueyville, Iowa. The comparison between observations and simulations corroborates the drop detachment threshold of 3.75 mm and indicates that splashing, as opposed to considering solely the rolling or bouncing of droplets that lack the kinetic energy to attach to the foliage, is the likely source of throughfall drops with diameters smaller than 1 mm. The predicted throughfall spatial

  3. Genetic Algorithm Based Microscale Vehicle Emissions Modelling

    Directory of Open Access Journals (Sweden)

    Sicong Zhu

    2015-01-01

    Full Text Available There is a need to match emission estimations accuracy with the outputs of transport models. The overall error rate in long-term traffic forecasts resulting from strategic transport models is likely to be significant. Microsimulation models, whilst high-resolution in nature, may have similar measurement errors if they use the outputs of strategic models to obtain traffic demand predictions. At the microlevel, this paper discusses the limitations of existing emissions estimation approaches. Emission models for predicting emission pollutants other than CO2 are proposed. A genetic algorithm approach is adopted to select the predicting variables for the black box model. The approach is capable of solving combinatorial optimization problems. Overall, the emission prediction results reveal that the proposed new models outperform conventional equations in terms of accuracy and robustness.

  4. A Size-based Ecosystem Model

    DEFF Research Database (Denmark)

    Ravn-Jonsen, Lars

     Ecosystem Management requires models that can link the ecosystem level to the operation level. This link can be created by an ecosystem production model. Because the function of the individual fish in the marine ecosystem, seen in trophic context, is closely related to its size, the model groups...... fish according to size. The model summarises individual predation events into ecosystem level properties, and thereby uses the law of conversation of mass as a framework. This paper provides the background, the conceptual model, basic assumptions, integration of fishing activities, mathematical...... completion, and a numeric implementation. Using two experiments, the model's ability to act as tool for economic production analysis and regulation design testing is demonstrated. The presented model is the simplest possible and is built on the principles of (i) size, as the attribute that determines...

  5. A model-based multisensor data fusion knowledge management approach

    Science.gov (United States)

    Straub, Jeremy

    2014-06-01

    A variety of approaches exist for combining data from multiple sensors. The model-based approach combines data based on its support for or refutation of elements of the model which in turn can be used to evaluate an experimental thesis. This paper presents a collection of algorithms for mapping various types of sensor data onto a thesis-based model and evaluating the truth or falsity of the thesis, based on the model. The use of this approach for autonomously arriving at findings and for prioritizing data are considered. Techniques for updating the model (instead of arriving at a true/false assertion) are also discussed.

  6. Overcoming limitations of model-based diagnostic reasoning systems

    Science.gov (United States)

    Holtzblatt, Lester J.; Marcotte, Richard A.; Piazza, Richard L.

    1989-01-01

    The development of a model-based diagnostic system to overcome the limitations of model-based reasoning systems is discussed. It is noted that model-based reasoning techniques can be used to analyze the failure behavior and diagnosability of system and circuit designs as part of the system process itself. One goal of current research is the development of a diagnostic algorithm which can reason efficiently about large numbers of diagnostic suspects and can handle both combinational and sequential circuits. A second goal is to address the model-creation problem by developing an approach for using design models to construct the GMODS model in an automated fashion.

  7. Agent Based Reasoning in Multilevel Flow Modeling

    DEFF Research Database (Denmark)

    Lind, Morten; Zhang, Xinxin

    2012-01-01

    to launch the MFM Workbench into an agent based environment, which can complement disadvantages of the original software. The agent-based MFM Workbench is centered on a concept called “Blackboard System” and use an event based mechanism to arrange the reasoning tasks. This design will support the new...

  8. A general model for membrane-based separation processes

    DEFF Research Database (Denmark)

    Soni, Vipasha; Abildskov, Jens; Jonsson, Gunnar Eigil;

    2009-01-01

    behaviour will play an important role. In this paper, modelling of membrane-based processes for separation of gas and liquid mixtures are considered. Two general models, one for membrane-based liquid separation processes (with phase change) and another for membrane-based gas separation are presented...

  9. Reproductive ethogram and mate selection in captive wild Senegalese sole (Solea senegalensis

    Directory of Open Access Journals (Sweden)

    Ignacio Carazo

    2016-12-01

    Full Text Available Senegalese sole (Solea senegalensis have a high potential for aquaculture that is hampered by reproductive behavioural problems. These problems result in limited breeder participation in spawning. The present study provided an ethogram and described mate selection and spawning of captive wild Senegalese sole. Two tanks of breeders were studied that had 29 and 25 breeders (mean weight = 1.6 ± 0.1 kg. The behaviour was studied during 20 periods of 24 hours: 10 periods where spawning events were recorded and 10 control periods without spawning events. Periods where spawning occurred had three times more locomotor activity than periods without spawning. Two distinct behaviours, termed the “following” behaviour and the “coupled swim”, were only observed during periods with spawning. The courtship sequence (n=12 began with males predominantly involved in “following” behaviours, whilst females remained mainly stationary on the bottom of the tank. Males rested on the females and encouraged the females to begin swimming. When the female began to swim the male swam under the female and the pair made a “coupled swim” to the surface to release gametes. Gamete release was strictly in pairs of one male with one female. Failed “coupled swims” without gamete release were 5.6 times more frequent than successful “coupled swims”. Mate selection was evident as the sole engaged in: paired spawning, males displayed to females, males encouraged females to spawn and females accepted or rejected the male’s advances. The mate selection process provided the opportunity for fish to dominate the spawning and also demonstrated how fish were excluded from spawning.

  10. Latitudinal comparison of spawning season and growth of 0-group sole, Solea solea (L.)

    Science.gov (United States)

    Vinagre, C.; Amara, R.; Maia, A.; Cabral, H. N.

    2008-07-01

    0-Group sole, Solea solea (Linnaeus, 1758) were sampled in four nursery grounds: two on the Northern French coast and two on the Portuguese coast. Juvenile sole were collected at the Vilaine estuary (Northern Bay of Biscay) in 1992, in the Authie estuary (Eastern English Channel) in 1997, and in the Douro and Tagus estuary (Northern and central Portugal, respectively) in 2005. Left lapilli otoliths were used to estimate age and investigate variability in growth rates and hatch dates. In the French study areas nursery colonisation ended in early June in the Vilaine estuary and in late June in the Authie estuary. In the Portuguese estuaries nursery colonisation ended in May in the Douro estuary and in late June in the Tagus estuary. Growth rates were higher in the Portuguese estuaries, 0.767 mm d -1 in the Tagus estuary and 0.903 mm d -1 in the Douro estuary. In the French nurseries, growth rates were estimated to be 0.473 mm d -1 in the Villaine estuary and 0.460 mm d -1 in the Authie estuary. Data on growth rates from other studies shows that growth rates are higher at lower latitudes, probably due to higher water temperature. Spawning took place between early January and early April in the Villaine estuary's coastal area in 1992. In 1997, in the Authie estuary spawning started in late January and ended in early April. On the Douro estuary's adjacent coast spawning started in mid-January and ended in late March, in 2005, while on the Tagus estuary's adjacent coast spawning started in mid-February and ended in mid-April, in the same year. Literature analysis of the spawning period of sole along a latitudinal gradient ranging from 38°N to 55°N in the Northeast Atlantic indicated that there is a latitudinal trend, in that spawning starts sooner at lower latitudes. Results support that local conditions, particularly hydrodynamics, may overrule general latitudinal trends.

  11. Busulfan administration produces sublethal effects on somatic tissues and inhibits gametogenesis in Senegalese sole juveniles.

    Science.gov (United States)

    Pacchiarini, T; Olague, E; Sarasquete, C; Cabrita, E

    2014-05-01

    Busulfan, a cytotoxic alkylating agent used for treatment of chronic myeloid leukemia has effects in mammalian germ cells. In fish species, the use of this compound is of special interest in intra and interspecies germ cell transplants. To determine the effects of busulfan in fish a previous range finding experiment was designed. Survival and growth rate of 150-days after hatching (150DAH) Senegalese sole (Solea senegalensis) juveniles was determined. In a second experiment, the effects of a sublethal busulfan dose in fish germ cell depletion and in somatic tissues were analysed. Sublethal effects of several busulfan treatments (B10-10 days after injection, B20-20 days after injection, B20÷-20 days after injection with double injection) were determined in somatic and gonadal tissues. Alterations were registered through histopathological techniques, TUNEL (cell apoptosis) and quantified at molecular level (Q-PCR analyses) using the vasa mRNAs (Ssvasa1-2 and Ssvasa3-4 mRNAs) as molecular markers for germinal cells in Senegalese sole juveniles. Several sublethal effects were observed with 40 mg kg⁻¹ busulfan, a non-lethal dose, such as: pyknosis in liver, increase of melanomacrophage centres and blood stagnation in spleen and interruption of gonadal development. Females were more affected by busulfan treatments than males in terms of germ cell disruption, since a significant decrease in the expression of both Ssvasa1-2 and Ssvasa3-4 markers was found in the gonad of treated females rather than males. At 10 days post-treatment (B10), females already presented a decrease in germ cell proliferation, as confirmed by Q-PCR. Ssvasa expression proved to be a reliable tool for the direct evaluation of the effects of busulfan on Senegalese sole gonadal development, proving that busulfan can be a suitable treatment for causing transient sterility in recipient gonads for germ cell transplantation.

  12. Comparing model predictions for ecosystem-based management

    DEFF Research Database (Denmark)

    Jacobsen, Nis Sand; Essington, Timothy E.; Andersen, Ken Haste

    2016-01-01

    Ecosystem modeling is becoming an integral part of fisheries management, but there is a need to identify differences between predictions derived from models employed for scientific and management purposes. Here, we compared two models: a biomass-based food-web model (Ecopath with Ecosim (Ew......E)) and a size-structured fish community model. The models were compared with respect to predicted ecological consequences of fishing to identify commonalities and differences in model predictions for the California Current fish community. We compared the models regarding direct and indirect responses to fishing...... on one or more species. The size-based model predicted a higher fishing mortality needed to reach maximum sustainable yield than EwE for most species. The size-based model also predicted stronger top-down effects of predator removals than EwE. In contrast, EwE predicted stronger bottom-up effects...

  13. Dietary deficiency of cobalamin presented solely as schizoaffective disorder in a lacto-vegetarian adolescent

    Directory of Open Access Journals (Sweden)

    Somashekarappa Dhananjaya

    2015-01-01

    Full Text Available Cobalamin is an important nutrient. It is not synthesized in human body and supplied only in nonvegetarian diet. Its deficiency reported with range of psychiatric disorders. Only four pediatric cases have been reported as psychiatric disorders. Authors report a case of dietary deficiency of cobalamin presenting solely as schizoaffective disorder without hematological/neurological manifestations. Early diagnosis and treatment of cobalamin deficiency is an opportunity to reverse pathophysiology. This case highlights the importance of diet history and serum cobalamin level in atypical psychiatric presentations.

  14. Softer, higher-friction flooring improves gait of cows with and without sole ulcers.

    Science.gov (United States)

    Flower, F C; de Passillé, A M; Weary, D M; Sanderson, D J; Rushen, J

    2007-03-01

    We studied dairy cows (n = 30) walking on concrete and on a soft, high-friction composite rubber surface to examine how flooring influenced gait and how this differed for cows with hoof lesions. Cows had hooves trimmed 9 wk after the trial and were classified as either with or without sole ulcers. Video recordings of the cows while walking were digitized using motion analysis software to calculate stride variables (length, height, overlap, duration, proportion of triple support, and speed). Gait was scored by a subjective scoring system (1 = sound to 5 = severely lame) and by a continuous visual analog scale for each of 7 gait attributes. Cows with sole ulcers walking on a composite rubber surface had longer strides (156.9 +/- 2.6 vs. 149.6 +/- 2.6 cm), higher stride heights (9.7 +/- 0.3 vs. 8.8 +/- 0.3 cm), more stride overlap (0.4 +/- 2.0 vs. -4.3 +/- 2.0 cm), shorter periods of triple support (3 legs in ground contact; 68.6 +/- 2.0 vs. 73.8 +/- 2.0%), walked faster (1.22 +/- 0.04 vs. 1.17 +/- 0.04 m/s) and had lower overall gait scores (2.9 +/- 0.1 vs. 3.1 +/- 0.1), better tracking-up (19 +/- 2 vs. 24 +/- 2), better joint flexion (29 +/- 2 vs. 33 +/- 2), more symmetric steps (31 +/- 3 vs. 36 +/- 3), and less reluctance to bear weight on their legs (12 +/- 2 vs. 16 +/- 2) compared with walking on concrete. Similar results were found for cows without sole ulcers. Most of the subjective gait measures could distinguish between cows with and without sole ulcers, but this was not the case for kinematic measures other than stride height. Cows with higher gait scores (more severe lameness) showed the greatest improvement in stride length (r = -0.51), triple support (r = 0.59), swing duration (r = -0.44), overall gait score (r = 0.46), and reluctance to bear weight (r = 0.66) when walking on the rubber surface compared with cows with lower gait scores. These results indicate that rubber flooring provides a more secure footing and is more comfortable to walk on

  15. Why sole-supplier vaccine markets may be here to stay.

    Science.gov (United States)

    Danzon, Patricia; Pereira, Nuno Sousa

    2005-01-01

    Given the structure of costs, demand, and competition, vaccine markets reach long-run equilibrium with one or very few suppliers at any point in time. Sole suppliers are less likely to exit and may have lower total social costs. Vaccine markets are dynamically competitive, with new, superior products displacing older, inferior products. Measures to address short-run supply disruptions include inventories, foreign sourcing, and improved technologies. Increasing the relative prices paid for new vaccines to levels that more closely reflect their social value compared to other new drugs and biologics is essential to achieving appropriate incentives for allocation of pharmaceutical R and D.

  16. Dietary Deficiency of Cobalamin Presented Solely as Schizoaffective Disorder in a Lacto-Vegetarian Adolescent.

    Science.gov (United States)

    Dhananjaya, Somashekarappa; Manjunatha, Narayana; Manjunatha, Rajashekaaiah; Kumar, Seetharamarao Udaya

    2015-01-01

    Cobalamin is an important nutrient. It is not synthesized in human body and supplied only in nonvegetarian diet. Its deficiency reported with range of psychiatric disorders. Only four pediatric cases have been reported as psychiatric disorders. Authors report a case of dietary deficiency of cobalamin presenting solely as schizoaffective disorder without hematological/neurological manifestations. Early diagnosis and treatment of cobalamin deficiency is an opportunity to reverse pathophysiology. This case highlights the importance of diet history and serum cobalamin level in atypical psychiatric presentations.

  17. Competition for and utilisation of sulfur in sole and intercrops of pea and barley

    DEFF Research Database (Denmark)

    Andersen, Mette Klindt; Hauggaard-Nielsen, Henrik; Jensen, Henning Høgh;

    2007-01-01

    .) and barley (Hordeum vulgare L.) were grown in a pot experiment as sole crops and intercrops with or without the addition of S in the form of gypsum. At three consecutive harvests total aboveground biomass and corresponding soil samples were taken for analysis. Harvested biomass was analysed for total S and N...... the pea component came to dominate the intercrop both with respect to yield and nutrient accumulation, accounting for 77% of total dry matter production, 90% of N uptake and 85% of S uptake, averaged across S treatments. LER values calculated on the basis of total aboveground dry matter, and N and S...

  18. Severe depression as the sole symptom of affective focal status epilepticus.

    Science.gov (United States)

    Dimitriadis, Konstantinos; Pfefferkorn, Thomas; Noachtar, Soheyl

    2014-05-14

    Depression as well as fear, joy and anger have been described as the semiological features of focal epileptic seizures. When emotions present as the sole symptoms of epileptic seizures, they may easily be misdiagnosed as a psychiatric disorder. We describe a patient with affective focal status epilepticus, secondary to limbic encephalitis, in which depression was the only clinical manifestation. Through EEG correlates the epileptic nature of depression could be proven. Furthermore, we discuss the association between epilepsy and depression, as well as the link between ictal depression and suicidal rates.

  19. Biglan Model Test Based on Institutional Diversity.

    Science.gov (United States)

    Roskens, Ronald W.; Creswell, John W.

    The Biglan model, a theoretical framework for empirically examining the differences among subject areas, classifies according to three dimensions: adherence to common set of paradigms (hard or soft), application orientation (pure or applied), and emphasis on living systems (life or nonlife). Tests of the model are reviewed, and a further test is…

  20. Functional Behavioral Assessment: A School Based Model.

    Science.gov (United States)

    Asmus, Jennifer M.; Vollmer, Timothy R.; Borrero, John C.

    2002-01-01

    This article begins by discussing requirements for functional behavioral assessment under the Individuals with Disabilities Education Act and then describes a comprehensive model for the application of behavior analysis in the schools. The model includes descriptive assessment, functional analysis, and intervention and involves the participation…

  1. A Network Formation Model Based on Subgraphs

    CERN Document Server

    Chandrasekhar, Arun

    2016-01-01

    We develop a new class of random-graph models for the statistical estimation of network formation that allow for substantial correlation in links. Various subgraphs (e.g., links, triangles, cliques, stars) are generated and their union results in a network. We provide estimation techniques for recovering the rates at which the underlying subgraphs were formed. We illustrate the models via a series of applications including testing for incentives to form cross-caste relationships in rural India, testing to see whether network structure is used to enforce risk-sharing, testing as to whether networks change in response to a community's exposure to microcredit, and show that these models significantly outperform stochastic block models in matching observed network characteristics. We also establish asymptotic properties of the models and various estimators, which requires proving a new Central Limit Theorem for correlated random variables.

  2. MQ-2 A Tool for Prolog-based Model Querying

    DEFF Research Database (Denmark)

    Acretoaie, Vlad; Störrle, Harald

    2012-01-01

    MQ-2 integrates a Prolog console into the MagicDraw1 modeling environment and equips this console with features targeted specifically to the task of querying models. The vision of MQ-2 is to make Prolog-based model querying accessible to both student and expert modelers by offering powerful query...

  3. An approach for activity-based DEVS model specification

    DEFF Research Database (Denmark)

    Alshareef, Abdurrahman; Sarjoughian, Hessam S.; Zarrin, Bahram

    2016-01-01

    activity-based behavior modeling of parallel DEVS atomic models. We consider UML activities and actions as fundamental units of behavior modeling, especially in the presence of recent advances in the UML 2.5 specifications. We describe in detail how to approach activity modeling with a set of elemental...

  4. Testing R&D-Based Endogenous Growth Models

    DEFF Research Database (Denmark)

    Kruse-Andersen, Peter Kjær

    2017-01-01

    R&D-based growth models are tested using US data for the period 1953-2014. A general growth model is developed which nests the model varieties of interest. The model implies a cointegrating relationship between multifactor productivity, research intensity, and employment. This relationship is est......-run growth rate of GDP per worker converges to between zero and 1.1 pct....

  5. A Stock Pricing Model Based on Arithmetic Brown Motion

    Institute of Scientific and Technical Information of China (English)

    YAN Yong-xin; HAN Wen-xiu

    2001-01-01

    This paper presents a new stock pricing model based on arithmetic Brown motion. The model overcomes the shortcomings of Gordon model completely. With the model investors can estimate the stock value of surplus companies, deficit companies, zero increase companies and bankrupt companies in long term investment or in short term investment.

  6. On the significance of the Nash-Sutcliffe efficiency measure for event-based flood models

    Science.gov (United States)

    Moussa, Roger

    2010-05-01

    When modelling flood events, the important challenge that awaits the modeller is first to choose a rainfall-runoff model, then to calibrate a set of parameters that can accurately simulate a number of flood events and related hydrograph shapes, and finally to evaluate the model performance separately on each event using multi-criteria functions. This study analyses the significance of the Nash-Sutcliffe efficiency (NSE) and proposes a new method to assess the performance of flood event models (see Moussa, 2010, "When monstrosity can be beautiful while normality can be ugly : assessing the performance of event-based-flood-models", Hydrological Science Journal, in press). We focus on the specific cases of events difficult to model and characterized by low NSE values, which we call "monsters". The properties of the NSE were analysed as a function of the calculated hydrograph shape and of the benchmark reference model. As application case, a multi-criteria analysis method to assess the model performance on each event is proposed and applied on the Gardon d'Anduze catchment. This paper discusses first the significance of the well-known Nash-Sutcliffe efficiency (NSE) criteria function when calculated separately on flood events. The NSE is a convenient and normalized measure of model performance, but does not provide a reliable basis for comparing the results of different case studies. We show that simulated hydrographs with low or negative values of NSE, called "monsters", can be due solely to a simple lag translation or a homothetic ratio of the observed hydrograph which reproduces the dynamic of the hydrograph, with acceptable errors on other criteria. In the opposite, results show that simulations with a NSE close to 1 can become "monsters" and give very low values (even negative) of the criteria function G, if the average observed discharged used as a benchmark reference model in the NSE is modified. This paper argues that the definition of an appropriate benchmark

  7. Multi-element otolith chemistry of juvenile sole ( Solea solea), whiting ( Merlangius merlangus) and European seabass ( Dicentrarchus labrax) in the Thames Estuary and adjacent coastal regions

    Science.gov (United States)

    Leakey, Chris D. B.; Attrill, Martin J.; Fitzsimons, Mark F.

    2009-04-01

    Estuaries are regarded as valuable nursery habitats for many commercially important marine fishes, potentially providing a thermal resource, refuge from predators and a source of abundant prey. To assess the extent of estuarine use by juvenile (0+) common sole ( Solea solea), whiting ( Merlangius merlangus) and European seabass ( Dicentrarchus labrax) we: (1) developed techniques to distinguish between estuarine and coastally-caught juveniles using otolith chemistry; and (2) examined the accuracy with which multi-elemental signatures could re-classify juveniles to their region of collection. High-resolution solution-based inductively coupled plasma mass spectrometry (HB-SB-ICPMS) was used to quantify 32 elements within the juvenile otoliths; 14 elements occurred above detection limits for all samples. Some elemental distributions demonstrated clear differences between estuarine and coastally-caught fish. Multivariate analysis of the otolith chemistry data resulted in 95-100% re-classification accuracy to the region of collection. Estuarine and coastal signatures were most clearly defined for sole which, compared to bass and whiting, have low mobility and are less likely to move from estuarine to coastal habitats between larval settlement and later migration to adult stocks. Sole were the only species to reveal an energetic benefit associated with an estuarine juvenile phase. The physiological ability of bass to access upper estuarine regions was consistent with some elemental data, while the high mobility and restricted range of whiting resulted in less distinct otolith chemistries.

  8. Conflict Detection and Merging in Model based SCM Systems

    OpenAIRE

    Waqar Mehmood; Arshad Ali

    2014-01-01

    This study presents a fine-grained approach to the problem of conflict detection and merging in model-based Software Configuration Management (SCM) systems. Traditional SCM systems uses textual or structured data to represent models at fine-grained level. Our approach is based on defining graph structure to represent models data at fine-grained level. The approach is based on transforming the textual or structured data into graph structure and then performing the diff, merge and evolution con...

  9. Statistical Model-Based Face Pose Estimation

    Institute of Scientific and Technical Information of China (English)

    GE Xinliang; YANG Jie; LI Feng; WANG Huahua

    2007-01-01

    A robust face pose estimation approach is proposed by using face shape statistical model approach and pose parameters are represented by trigonometric functions. The face shape statistical model is firstly built by analyzing the face shapes from different people under varying poses. The shape alignment is vital in the process of building the statistical model. Then, six trigonometric functions are employed to represent the face pose parameters. Lastly, the mapping function is constructed between face image and face pose by linearly relating different parameters. The proposed approach is able to estimate different face poses using a few face training samples. Experimental results are provided to demonstrate its efficiency and accuracy.

  10. Simplified Atmospheric Dispersion Model andModel Based Real Field Estimation System ofAir Pollution

    Institute of Scientific and Technical Information of China (English)

    2015-01-01

    The atmospheric dispersion model has been well developed and applied in pollution emergency and prediction. Based on thesophisticated air diffusion model, this paper proposes a simplified model and some optimization about meteorological andgeological conditions. The model is suitable for what is proposed as Real Field Monitor and Estimation system. The principle ofsimplified diffusion model and its optimization is studied. The design of Real Field Monitor system based on this model and itsfundamental implementations are introduced.

  11. Multimedia Data Modeling Based on Temporal Logic and XYZ System

    Institute of Scientific and Technical Information of China (English)

    MA Huadong; LIU Shenquan

    1999-01-01

    This paper proposes a new approach to modeling multimedia data. The newapproach is the multimedia data model based on temporal logic and XYZSystem. It supports the formal specifications in a multimedia system.Using this model, we can not only specify information unitsbut also design and script a multimedia title in an unified framework.Based on this model, an interactive multimedia authoring environment hasbeen developed.

  12. Physics-Based Pneumatic Hammer Instability Model Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Florida Turbine Technologies (FTT) proposes to conduct research necessary to develop a physics-based pneumatic hammer instability model for hydrostatic bearings...

  13. Image-Based Modeling of Plants and Trees

    CERN Document Server

    Kang, Sing Bang

    2009-01-01

    Plants and trees are among the most complex natural objects. Much work has been done attempting to model them, with varying degrees of success. In this book, we review the various approaches in computer graphics, which we categorize as rule-based, image-based, and sketch-based methods. We describe our approaches for modeling plants and trees using images. Image-based approaches have the distinct advantage that the resulting model inherits the realistic shape and complexity of a real plant or tree. We use different techniques for modeling plants (with relatively large leaves) and trees (with re

  14. Comparing Ray-Based and Wave-Based Models of Cross-Beam Energy Transfer

    Science.gov (United States)

    Follett, R. K.; Edgell, D. H.; Shaw, J. G.; Froula, D. H.; Myatt, J. F.

    2016-10-01

    Ray-based models of cross-beam energy transfer (CBET) are used in radiation-hydrodynamics codes to calculate laser-energy deposition. The accuracy of ray-based CBET models is limited by assumptions about the polarization and phase of the interacting laser beams and by the use of a paraxial Wentzel-Kramers-Brillouin (WKB) approximation. A 3-D wave-based solver (LPSE-CBET) is used to study the nonlinear interaction between overlapping laser beams in underdense plasma. A ray-based CBET model is compared to the wave-based model and shows good agreement in simple geometries where the assumptions of the ray-based model are satisfied. Near caustic surfaces, the assumptions of the ray-based model break down and the calculated energy transfer deviates from wave-based calculations. This material is based upon work supported by the Department of Energy National Nuclear Security Administration under Award Number DE-NA0001944.

  15. Model-Based Reasoning in Humans Becomes Automatic with Training.

    Directory of Open Access Journals (Sweden)

    Marcos Economides

    2015-09-01

    Full Text Available Model-based and model-free reinforcement learning (RL have been suggested as algorithmic realizations of goal-directed and habitual action strategies. Model-based RL is more flexible than model-free but requires sophisticated calculations using a learnt model of the world. This has led model-based RL to be identified with slow, deliberative processing, and model-free RL with fast, automatic processing. In support of this distinction, it has recently been shown that model-based reasoning is impaired by placing subjects under cognitive load--a hallmark of non-automaticity. Here, using the same task, we show that cognitive load does not impair model-based reasoning if subjects receive prior training on the task. This finding is replicated across two studies and a variety of analysis methods. Thus, task familiarity permits use of model-based reasoning in parallel with other cognitive demands. The ability to deploy model-based reasoning in an automatic, parallelizable fashion has widespread theoretical implications, particularly for the learning and execution of complex behaviors. It also suggests a range of important failure modes in psychiatric disorders.

  16. Probabilistic reasoning for assembly-based 3D modeling

    KAUST Repository

    Chaudhuri, Siddhartha

    2011-01-01

    Assembly-based modeling is a promising approach to broadening the accessibility of 3D modeling. In assembly-based modeling, new models are assembled from shape components extracted from a database. A key challenge in assembly-based modeling is the identification of relevant components to be presented to the user. In this paper, we introduce a probabilistic reasoning approach to this problem. Given a repository of shapes, our approach learns a probabilistic graphical model that encodes semantic and geometric relationships among shape components. The probabilistic model is used to present components that are semantically and stylistically compatible with the 3D model that is being assembled. Our experiments indicate that the probabilistic model increases the relevance of presented components. © 2011 ACM.

  17. A resonance based model of biological evolution

    Science.gov (United States)

    Damasco, Achille; Giuliani, Alessandro

    2017-04-01

    We propose a coarse grained physical model of evolution. The proposed model 'at least in principle' is amenable of an experimental verification even if this looks as a conundrum: evolution is a unique historical process and the tape cannot be reversed and played again. Nevertheless, we can imagine a phenomenological scenario tailored upon state transitions in physical chemistry in which different agents of evolution play the role of the elements of a state transition like thermal noise or resonance effects. The abstract model we propose can be of help for sketching hypotheses and getting rid of some well-known features of natural history like the so-called Cambrian explosion. The possibility of an experimental proof of the model is discussed as well.

  18. Demand forecast model based on CRM

    Science.gov (United States)

    Cai, Yuancui; Chen, Lichao

    2006-11-01

    With interiorizing day by day management thought that regarding customer as the centre, forecasting customer demand becomes more and more important. In the demand forecast of customer relationship management, the traditional forecast methods have very great limitation because much uncertainty of the demand, these all require new modeling to meet the demands of development. In this paper, the notion is that forecasting the demand according to characteristics of the potential customer, then modeling by it. The model first depicts customer adopting uniform multiple indexes. Secondly, the model acquires characteristic customers on the basis of data warehouse and the technology of data mining. The last, there get the most similar characteristic customer by their comparing and forecast the demands of new customer by the most similar characteristic customer.

  19. An event-based model for contracts

    Directory of Open Access Journals (Sweden)

    Tiziana Cimoli

    2013-02-01

    Full Text Available We introduce a basic model for contracts. Our model extends event structures with a new relation, which faithfully captures the circular dependencies among contract clauses. We establish whether an agreement exists which respects all the contracts at hand (i.e. all the dependencies can be resolved, and we detect the obligations of each participant. The main technical contribution is a correspondence between our model and a fragment of the contract logic PCL. More precisely, we show that the reachable events are exactly those which correspond to provable atoms in the logic. Despite of this strong correspondence, our model improves previous work on PCL by exhibiting a finer-grained notion of culpability, which takes into account the legitimate orderings of events.

  20. Changes in Biochemical, Sensory and Microbiological Quality Indices of Common Sole (Solea solea) from the Mediterranean Sea, During Ice Storage

    OpenAIRE

    ÖZOĞUL, Yeşim; BOĞA, Esmeray KULEY; Tokur, Bahar; Özoğul, Fatih

    2011-01-01

    The quality of wild common sole (Solea solea) stored in ice was investigated by chemical (K value, biogenic amines, protein degradation (SDS and SDS-PAGE), pH, peroxide value (PV), free fatty acids (FFA), total volatile basic nitrogen (TVB-N), tiobarbituric acid (TBA) analyses), sensory (raw and cooked fish) and microbiological methods. The quality of common sole decreased on day 16 (fair quality- B) and they were no longer acceptable on day 20 (unacceptable quality-C). When common sole were ...