Motives for SMS Use

NARCIS (Netherlands)

Peters, O.; Almekinders, Johan; van Buren, Ruud; Snippers, Roy; Wessels, Jacqueline

This study was designed to identify, from a uses-and-gratifications point of view, the motives that young people in the age of 12 to 25 have for using SMS. The study also aimed to assess whether these SMS motives are related to age, gender, current education, mobile phone experience, SMS experience

PERANGKAT LUNAK UNTUK EKTRAKSI ISI DOKUMEN MULTIFORMAT DENGAN MENGGUNAKAN SMS DAN FAXIMILE

Directory of Open Access Journals (Sweden)

Ahmad Hoirul Basori

2005-01-01

Full Text Available Normal 0 false false false IN X-NONE X-NONE MicrosoftInternetExplorer4 Dokumen multiformat merupakan salah satu bentuk file yang disimpan dalam komputer  dan  banyak digunakan oleh  masyarakat saat ini.Setiap dokumen mempunyai karakteristik berbeda  dan memerlukan software yang berbeda untuk setiap file dokumen. Sedangkan perkembangan handphone yang semakin pesat membuat masyarakat lebih familiar menggunakan handphone daripada menggunakan komputer.proses pengambilan dokumen dapat terhambat jika user yang memerlukan dokumen multiformat tidak mempunyai keahlian komputer. Pada pengerjaan penelitian ini, teknologi yang digunakan untuk pengambilan dokumen multiformat adalah teknologi SMS dan mesin Faximile.sedangkan untuk pemodelan sistemnya teknologi yang digunakan adalah Unified Modelling Language dengan Rational Rose Enterprise 2000, serta  database Microsoft Access untuk penyimpanan data SMS. Untuk membangun aplikasi teknologi yang digunakan adalah Microsoft Visual Basic 6.0. Hal ini disebabkan dokumen multiformat pada penelitian ini kebanyakan merupakan produksi Microsoft sehingga antara teknologi yang digunakan dan dokumen multiformat saling mempunyai kesesuaian.   Uji coba dilakukan dengan cara melakukan pengiriman dokumen multiformat melalui SMS dan mengeluarkan outputnya ke dalam mesin faximile. Uji coba ini mencakup proses pembacaan data SMS, penyimpanan data SMS ke dalam database, pengiriman dokumen ke mesin fax, download page online, serta penambahan hak akses user melalui SMS. Hasil uji coba menunjukkan adanya permasalahan pada pengiriman dokumen multiformat yang berada dalam keadaan terproteksi. Permasalahan ini dapat diselesaikan dengan menghilangkan password yang ada pada dokumen multiformat.   Kata Kunci: SMS (Short Message Service, Ektraksi Dokumen, Mesin Fax.

Study of the low pressure (Black Phase) SmS properties

International Nuclear Information System (INIS)

Bordier, G.

1987-03-01

SmS has been studied for its transition from the low pressure black phase to the high pressure intermediate valence phase; but the black phase properties seem to be very rich. The variations which pressure of the low-temperature electronic transport properties show the existence of a semi-metallic phase within the black phase domain in a pressure-temperature diagram, for a pressure above 4 kbar, which corresponds to the so-called B'phase. We study the insulating low pressure phase with a model involving acceptor like states. Using electronic paramagnetic resonance experiments we observe a square symmetry trivalent samarium ion neighbour of a sulfure defect, and magnetically coupled with the lattice. This defect exists in two nearly symmetric configurations and the resonance line broadens with temperature in an actived way. It gives rise to metastable effects yielding conductivity relaxations, analysed with stretched exponential laws, because the defect traps magnetically conduction electrons forming a bound magnetic polaron. The relaxation time at zero field is temperature actived. We develop a phenomenological model that gives the good orders of magnitude for the trapping barrier and for the critical field corresponding to the maximum of the low temperature magnetoresistance [fr

SMS and Web-Based e-Government Model Case Study: Citizens Complaints Management System at District of Gihosha –Burundi

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Mugenzi Thierry

2017-01-01

Full Text Available E-Government basically comprises the use of electronic communications technologies such as the internet, in enhancing and advancing the citizens access to public services. In most developing countries including Burundi, citizens are facing many difficulties for accessing public services. One of the identified problems is the poor quality of service in managing citizens’ complaints. This study proposes an SMS and web based e-Government Model as a solution. In this study, a case study of a complaint management system at District of Gihosha has been used as a reference to prove that SMS and Web based e-Government Model can enhances the access of public services. The objective of this study is the development of an SMS and web-based system that can enhances the process and the management of citizens’ complaints at District of Gihosha. The system has been developed using PHP as front end, Apache as web server, MySQL as Database and Gammu as SMS gateway. The obtained results after testing the system shows that all the functionalities of the developed system worked properly. Thus, the SMS and web based complaint management system developed is considered to be effective.

PEMBANGUNAN SISTEM INFORMASI LAYANAN PELANGGAN DI PDAM TIRTAMARTA BERBASIS SMS

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Tedy Setiadi

2008-01-01

Full Text Available Perusahaan Daerah Air Minum (PDAM Tirtamarta Yogyakarta merupakan perusahaan air minum yang memiliki lebih 35.000 pelanggan. Dengan banyaknya pelanggan tersebut, PDAM dituntut untuk terus meningkatkan pelayanan kepada pelanggan. Salah satunya layanan informasi tentang informasi tagihan serta permohonan reparasi dari pelanggan. Selama ini masalah yang dihadapi adalah pelanggan harus menunggu datangnya surat tentang tagihan yang harus dibayar dan kalau ada kerusakan untuk mengajukan reparasi harus datang untuk mengisi formulir terlebih dahulu.. Untuk itu dalam penelitian ini telah dibangun Sistem Informasi Layanan Pelanggan di PDAM Berbasis SMS. Metode penelitian yang dilakukan melalui pendekatan waterfall yaitu menganalisis kebutuhan pengguna, mencermati model bisnis yang ada, pengembangan algoritma tagihan rekening air,pembuatan basis data, koding dengan Visual Basic 6.0, Protocol Data Unit (PDU sebagai bahasa SMS, serta AT Command sebagai perintah untuk komunikasi ponsel dengan PC. Setelah program jadi, dilakukan uji program dengan metode black box test dan alpha test. Penelitian yang dibuat menghasilkan sebuah sistem Layanan Informasi Pelanggan yang membantu memudahkan dan mempercepat layanan permohonan reparasi dan informasi tagihan pelanggan yang akan jatuh tempo. Kata Kunci: Layanan, Pelanggan, Reparasi, Tagihan, SMS

SMS: still an effective mobile marketing strategy

Directory of Open Access Journals (Sweden)

Irene Garcia Medina

2011-05-01

Full Text Available Os telefones móveis tornaram-se mais do que ferramentas pessoais para conversar com familiares e conhecidos. Tornaram-se assistentes da vida diária. Com aplicações móveis cada vez mais diversificadas, o telefone móvel tornou-se um poderoso meio de comunicação. Esse paper estuda a natureza da comunicação móvel e o uso de uma aplicação móvel, o SMS (Serviço de Mensagens Curtas, na comunicação de marketing além de discutir quais diferentes fatores são importantes para se desenvolver mensagens SMS que possam aumentar o interesse e o número de respostas dos receptores, dessa forma aumentando a eficiência de uma campanha SMS.

Developing a Resilient Just Culture in SMS and FRMS : EasyJet Implementation

NARCIS (Netherlands)

Stewart, S.; Akselsson, R.; Koornneef, F.

2009-01-01

Chapter 7: Developing a Resilient Just Culture in SMS and FRMS – easyJet Implementation The European Commission HILAS project (Human Integration into the Lifecycle of Aviation Systems - a project supported by the European Commission’s 6th Framework between 2005-2009) was focused on using human

A security scheme of SMS system

Science.gov (United States)

Zhang, Fangzhou; Yang, Hong-Wei; Song, Chuck

2005-02-01

With the prosperous development and the use of SMS, more and more important information need to be transferred through the wireless and mobile networks by the users. But in the GSM/GPRS network, the SMS messages are transferred in text mode through the signaling channel and there is no integrality for SMS messages. Because of the speciality of the mobile communications, the security of signaling channel is very weak. So we need to improve and enhance the security and integrality of SMS. At present, developed investigation based on SMS security is still incomplete. The key distribution and management is not perfect to meet the usability in a wide area. This paper introduces a high-level security method to solve this problem. We design the Secure SMS of GSM/GPRS in order to improve the security of the important information that need to be transferred by the mobile networks. Using this method, we can improve the usability of E-payment and other mobile electronic commerce.

Mobile phone use and willingness to pay for SMS for diabetes in Bangladesh.

Science.gov (United States)

Shariful Islam, Sheikh Mohammed; Lechner, Andreas; Ferrari, Uta; Seissler, Jochen; Holle, Rolf; Niessen, Louis W

2016-03-01

Mobile phone SMS is increasingly used as a means of communication between patients and their healthcare providers in many countries of the world. We investigated mobile phone use and factors associated with willingness-to-pay (WTP) for diabetes SMS among patients with type 2 diabetes in Bangladesh. As part of a randomized controlled study, in 515 patients with type 2 diabetes, socioeconomic status, mobile phone use, WTP for diabetes SMS, anthropometry and HbA1c were measured. Multivariate regression was used to identify factors associated with WTP. The median (interquartile range [IQR]) of WTP for diabetes SMS was 20 (45) Bangladesh Taka (BDT) (1 BDT = 0.013 US$). WTP was significantly higher for males [OR 2.4, 95% CI (1.0-5.7)], patients with household income >50 000 BDT [4.6 (1.1-20.4)] and those with primary education [5.6 (1.2-26.6)] and secondary and higher education [5.2 (1.4-19.6)]. The high proportion of mobile phone use and WTP for diabetes SMS are encouraging as possible strategy to use such technologies and deserve further evaluation. © The Author 2015. Published by Oxford University Press on behalf of Faculty of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Uus turunduskangelane SMS / Merit Raju

Index Scriptorium Estoniae

Raju, Merit

2002-01-01

Lühisõnum SMS (Short Message Service) ja multimeediasõnum MMS (Multimedia Messaging System) - uued võimalused reklaami edastamiseks klientidele. Kommenteerib Henri Österlund. Lisa: SMS-reklaami võimalused

Electronic folklore among teenagers: SMS messages

Directory of Open Access Journals (Sweden)

Cvjetićanin Tijana

2006-01-01

Full Text Available The development of ICT media made way for a new form of folklore communication. Newly developed media, such as mobile phones, make it possible for their users to participate in electronically mediated communication, thus approaching the form of oral communication. The exchange of special type of SMS text messages represents a new way of transmitting contemporary folklore short forms. These messages use poetic language, they have standard style themes, patterns and formulas, and they form different genres and categories corresponding with already existing familiar folklore forms. The communication process that happens during the exchange of these messages also has folklore’s characteristics: it takes place within small groups, the communication is informal, the texts circulate in chain style, and undergo different transformation which generates the making of variants, etc. This form of electronic folklore is especially popular among teenagers, where it’s social functions and meanings are also most emphasized. Within this population, it adds to an older tradition of children’s written folklore poetry albums. Like poetry albums, SMS exchange influences the development of girls’ gender identity, providing also a socially defined channel for contacts between the sexes. It also functions as a mechanism of socialization and stratification within the group. At the same time, it creates a new field of meaning, which derives from the very media’s novelty and significance. In this sense, the exchange of SMS represents a symbolic act of acknowledging one’s belonging to the group of mobile telephone users. In this way, a new phenomenon is being symbolically processed through a new form of folklore.

Study of SmS properties in the low pressure phase (black phase)

International Nuclear Information System (INIS)

Bordier, G.

1986-01-01

SmS was studied for the transition from low pressure phase (black phase) to high pressure phase with an intermediate valence. But the study of the black phase is very rich. The variations of electron transport properties with pressure at low temperature show a semi-metal phase located, in the pressure-temperature diagram in the black phase for pressure over 4 kbars, corresponding to the phase B'of the doping-temperature diagram. Electron spin resonance shows a lack of sulfur and nearby this defect a samarium ion, magnetically coupled with the matrix, presents a divalent trivalent transition. Resonance lines are broadened with temperature. Conductivity relaxations occur at low pressure and low temperature by trapping a conduction electron, by magnetic exchange giving a bounded magnetic polaron. The relaxation time at null magnetic field is activated. An approximation of trapping barrier and critical field corresponding the maximum magnetoresistance is given by a model [fr

The SMS-GPS-Trip-Method

DEFF Research Database (Denmark)

Reinau, Kristian Hegner; Harder, Henrik; Weber, Michael

2015-01-01

This article presents a new method for collecting travel behavior data, based on a combination of GPS tracking and SMS technology, coined the SMS–GPS-Trip method. The state-of-the-art method for collecting data for activity based traffic models is a combination of travel diaries and GPS tracking...

SMS Messaging Applications

CERN Document Server

Pero, Nicola

2009-01-01

Cell phones are the most common communication device on the planet, and Short Message Service (SMS) is the chief channel for companies to offer services, accept requests, report news, and download binary files over cell phones. This guide describes the protocols and best practices (things that ensure you won't get sued or lose your right to offer a service) you need to know to make SMS messaging part of an organizational service. Issues such as character sets, differences among vendors, common practices in Europe and North America, and API choices are covered.

Effects of a somatostatin derivative (SMS 201-995) on postprandial hyperglycemia in insulin-dependent diabetics studied by means of a closed-loop device.

Science.gov (United States)

Nosari, I; Lepore, G; Querci, F; Maglio, M L; Sileo, F; Pagani, G

1989-06-01

We studied the effects of a premeal sc injection of an analog of somatostatin (SMS 201-995, Sandoz) on the postprandial glycemic excursions, insulin requirement and hormone profiles (GH, glucagon and C-peptide) in 8 IDDM patients (diabetes duration 14.0 +/- 6.5 yr, daily insulin requirement 36 +/- 6.4 U) maintained normoglycemic by connecting them to a closed-loop insulin infusion system (Betalike, Genoa). The morning of the test the patients were connected to the Betalike and their glucose levels stabilized for at least 4 h. At 13:00 h the study was begun with a sc injection of 50 micrograms of SMS 201-995 or placebo (randomly) and a standardized mixed meal (800 Kcal) was given. Blood samples were obtained 0, 15, 30, 60, 120 and 180 min after the injection. Each patient was tested both with SMS 201-995 and placebo. Postmeal glycemic peaks were decreased after SMS 201-995 (119.6 +/- 5.4 mg/dl vs 149.1 +/- 4.2; p less than 0.05) as well as insulin requirements (3.2 +/- 0.8 U vs 13.3 +/- 1.9; p less than 0.01) for the 180 min postprandial period. Similarly, glucagon level was reduced 30 min postprandially (24 +/- 6 pg/ml vs 59 +/- 24; p less than 0.05) and so GH level only 180 min after lunch (p less than 0.05). The premeal injection of SMS decreases postprandial glycemic excursions and the corresponding insulin requirement. The action of SMS 201-995 may be mainly mediated by the suppression of postprandial glucagon peak.

On mechanism of substructure formation in SmS during isomorphic phase transformations

International Nuclear Information System (INIS)

Aptekar', I.L.; Ivanov, V.I.; Tonkov, E.Yu.; Shmyt'ko, I.M.

1986-01-01

X-ray diffraction study of substructure characteristics of SmS samples subjected to treatment at different temrerature and pressure in media with different viscosity ( graphite, silicon oil) for realization of P-M-P transformations ( p-semiconductor phase, M - high pressure phase) is performed. It is assumed that with M - phase formation P - matrix volume relaxation delays, therefore the new phase particles occupy smaller volume than the initial matrix which causes the M - phase disorientation. The difference between the phase transformation rate and deformation rate under the pressure in media with various viscosity results in arising different substructural characteristics

PRESENT STATE AND THE PERSPECTIVES OF SMS MARKETING IN ROMANIA

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Mihai COSTEA

2014-06-01

Full Text Available The SMS (Short Message Service,which emerged at the beginning of the 90s as a result of the telephone services’ need for diversification, it is now used in the communication campaigns involving customized messaging, but also in general messaging campaigns sent both to the existing clients and to the potential ones. Thus, the SMS became widely used, turning into one of the most popular instruments of Mobile marketing and, soon becoming a separate concept named the SMS Marketing. Although there is the preconception that the mobile marketing and, namely, the SMS marketing is intended to be used primarily by the big corporations, which have the power and also the availability to invest substantial amounts of money in this sort of programs, the present paper intends precisely to debunk these preconceptions and, hence, to present the advantage of such marketing campaigns for the segment consisting of small and middle companies in Romania.

Wearable Sensor/Device (Fitbit One) and SMS Text-Messaging Prompts to Increase Physical Activity in Overweight and Obese Adults: A Randomized Controlled Trial

Science.gov (United States)

Cadmus-Bertram, Lisa A.; Natarajan, Loki; White, Martha M.; Madanat, Hala; Nichols, Jeanne F.; Ayala, Guadalupe X.; Pierce, John P.

2015-01-01

Abstract Background: Studies have shown self-monitoring can modify health behaviors, including physical activity (PA). This study tested the utility of a wearable sensor/device (Fitbit® One™; Fitbit Inc., San Francisco, CA) and short message service (SMS) text-messaging prompts to increase PA in overweight and obese adults. Materials and Methods: Sixty-seven adults wore a Fitbit One tracker for 6 weeks; half were randomized to also receive three daily SMS-based PA prompts. The Fitbit One consisted of a wearable tracker for instant feedback on performance and a Web site/mobile application (app) for detailed summaries. Outcome measures were objectively measured steps and minutes of PA by intensity using two accelerometers: Actigraph™ (Pensacola, FL) GT3X+ (primary measure) at baseline and Week 6 and Fitbit One (secondary measure) at baseline and Weeks 1, 2, 3, 4, 5, and 6. Results: Mixed-model repeated-measures analysis of primary measures indicated a significant within-group increase of +4.3 (standard error [SE]=2.0) min/week of moderate- to vigorous-intensity PA (MVPA) at 6-week follow-up (p=0.04) in the comparison group (Fitbit only), but no study group differences across PA levels. Secondary measures indicated the SMS text-messaging effect lasted for only 1 week: the intervention group increased by +1,266 steps (SE=491; p=0.01), +17.8 min/week MVPA (SE=8.5; p=0.04), and +38.3 min/week total PA (SE=15.9; p=0.02) compared with no changes in the comparison group, and these between-group differences were significant for steps (p=0.01), fairly/very active minutes (p<0.01), and total active minutes (p=0.02). Conclusions: These data suggest that the Fitbit One achieved a small increase in MVPA at follow-up and that the SMS-based PA prompts were insufficient in increasing PA beyond 1 week. Future studies can test this intervention in those requiring less help and/or test strategies to increase participants' engagement levels. PMID:26431257

VIRTUAL WEB PROMOSI DAN RESERVASI HOTEL BERBASIS WEB DAN VIA SMS PADA HOTEL DIAMOND

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Alexander Setiawan

2012-01-01

Full Text Available Web and SMS is a new development that is useful for many people as a data exchange media. In the business world, especially for marketing use, by using those two media business can be performed globally so that informations are fast and easily spread all over the world. From this problem born an idea to promote Diamond Hotel by using web and a facility to reserve room using SMS. This Application was created by using VB 6 language and using AT command to communicate with cellphone. Meanwhile, data that flow between system and cellphone are in the form of Protocol Data Unit. System had been tested by sending SMS request from a cellphone and system sent back SMS response as requested by user.

Use of short message service (SMS to improve malaria chemoprophylaxis compliance after returning from a malaria endemic area

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Boutin Jean-Paul

2009-10-01

Full Text Available Abstract Background Malaria chemoprophylaxis compliance is suboptimal among French soldiers despite the availability of free malaria chemoprophylaxis and repeated health education before, during and after deployment to malaria endemic areas. Methods In 2007, a randomized controlled study was performed among a cohort of French soldiers returning from Côte d'Ivoire to assess the feasibility and acceptability of sending a daily short message service (SMS reminder message via mobile device to remind soldiers to take their malaria chemoprophylaxis, and to assess the impact of the daily reminder SMS on chemoprophylaxis compliance. Malaria chemoprophylaxis consisted of a daily dose of 100 mg doxycycline monohydrate, which began upon arrival in Côte d'Ivoire and was to be continued for 28 days following return to France. Feasibility and acceptability were assessed by questionnaire. Cohort members were followed for a 28 day period, with compliance assessed by use of an electronic medication monitoring device, from which several indicators were developed: daily proportion of compliant individuals, average number of pills taken, and early discontinuation. Results Among 424 volunteers randomized to the study, 47.6% were assigned to the SMS group and 52.3% to the control group. Approximately 90% of subjects assigned to the SMS group received a daily SMS at midday during the study. Persons of the SMS group agreed more frequently that SMS reminders were very useful and that the device was not annoying. Compliance did not vary significantly between groups across the compliance indicators. Conclusion SMS did not increase malaria chemoprophylaxis compliance above baseline, likely because the persons did not benefit from holidays after the return and stayed together. So the reminder by SMS was noted by all subjects of the study. Another study should be done to confirm these results on soldiers going on holidays from employment after return or with individual

78 FR 76391 - Proposed Enhancements to the Motor Carrier Safety Measurement System (SMS) Public Web Site

Science.gov (United States)

2013-12-17

...-0392] Proposed Enhancements to the Motor Carrier Safety Measurement System (SMS) Public Web Site AGENCY... proposed enhancements to the display of information on the Agency's Safety Measurement System (SMS) public Web site. On December 6, 2013, Advocates [[Page 76392

Experimental Simulation-Based Performance Evaluation of an SMS-Based Emergency Geolocation Notification System

Directory of Open Access Journals (Sweden)

Isibor Osebor

2017-01-01

Full Text Available In an emergency, a prompt response can save the lives of victims. This statement generates an imperative issue in emergency medical services (EMS. Designing a system that brings simplicity in locating emergency scenes is a step towards improving response time. This paper therefore implemented and evaluated the performance of an SMS-based emergency geolocation notification system with emphasis on its SMS delivery time and the system’s geolocation and dispatch time. Using the RAS metrics recommended by IEEE for evaluation, the designed system was found to be efficient and effective as its reliability stood within 62.7% to 70.0% while its availability stood at 99% with a downtime of 3.65 days/year.

Can we compare SMS marketing to traditional marketing communications?

OpenAIRE

Roozen, Irene; Genin, Emile

2008-01-01

Nowadays most companies acknowledge the importance of SMS marketing in reaching and interacting with their customers (Kavassalis et al. 2003; Dickinger et al. 2004; Tsang, Ho & Liang 2004; Sharl, Dickinger & Murphy 2005; Muk 2007). However, there is much discussion in the press regarding the effectiveness when it comes to SMS marketing. Are customers willing to accept, reading and using SMS messages: how effective is SMS marketing compared to traditional marketing communications? The goal of ...

PEMBANGUNAN SISTEM INFORMASI LAYANAN PELANGGAN DI PDAM TIRTAMARTA BERBASIS SMS

Directory of Open Access Journals (Sweden)

Tedy Setiadi

2013-04-01

Full Text Available Perusahaan Daerah Air Minum (PDAM Tirtamarta Yogyakarta merupakan perusahaan air minum yang memiliki lebih 35.000 pelanggan. Dengan banyaknya pelanggan tersebut, PDAM dituntut untuk terus meningkatkan pelayanan kepada pelanggan. Salah satunya layanan informasi tentang informasi tagihan serta permohonan reparasi dari  pelanggan. Selama ini masalah yang dihadapi adalah pelanggan harus menunggu datangnya surat tentang tagihan yang harus dibayar dan kalau ada kerusakan untuk mengajukan reparasi harus datang untuk mengisi formulir terlebih dahulu.. Untuk itu dalam penelitian ini telah dibangun Sistem Informasi Layanan Pelanggan di PDAM Berbasis SMS. Metode penelitian yang dilakukan melalui pendekatan waterfall yaitu menganalisis kebutuhan pengguna, mencermati model bisnis yang ada, pengembangan algoritma tagihan rekening air,pembuatan basis data, koding dengan Visual Basic 6.0, Protocol Data Unit (PDU sebagai bahasa SMS, serta  AT Command sebagai perintah untuk komunikasi ponsel dengan PC. Setelah program jadi, dilakukan uji program dengan metode black box test dan alpha test.  Penelitian yang dibuat menghasilkan sebuah sistem Layanan Informasi Pelanggan yang membantu memudahkan dan mempercepat layanan permohonan reparasi dan informasi tagihan pelanggan yang akan jatuh tempo.

Can ‘Mobile Platform’ and ‘Permission Marketing’ dance a tango to the consumers' tune? Modeling adoption of ‘SMS based Permission Advertising’

OpenAIRE

Prerna Bamoriya

2015-01-01

Many a times situation of advertising clutter is further aggrieved by the markers’ intrusive practices i.e. not asking for consumer’s explicit permission. It results in consumers’ alienation and reduced advertising effectiveness. Solution could be integration of Permission Marketing with an innovative advertising platform like Mobile. This study aimed to develop and validate a comprehensive model for understanding consumers’ adoption behavior towards SMS Based Permission Advertising (SBPA). F...

Sizes of X-ray radiation coherent domains in thin SmS films and their visualization

Science.gov (United States)

Sharenkova, N. V.; Kaminskii, V. V.; Petrov, S. N.

2011-09-01

The size of X-ray radiation coherent domains (250 ± 20 Å) is determined in a thin polycrystalline SmS film using X-ray diffraction patterns (θ-2θ scanning, DRON-2 diffractometer, Cu K α radiation) and the Selyakov-Scherrer formula with allowance for the effect of microstrains. An image of this film is taken with a transmission electron microscope, and regions with a characteristic size of 240 Å are clearly visible in it. It is concluded that X-ray radiation coherent domains are visualized.

Application of the three-body model to the reactions 6Li(3He,t 3He)3He and 6Li(3He,3He3He)3H

International Nuclear Information System (INIS)

Haftel, M.I.; Allas, R.G.; Beach, L.A.; Bondelid, R.O.; Petersen, E.L.; Slaus, I.; Lambert, J.M.; Treado, P.A.

1977-01-01

Experimental and theoretical cross sections are presented for the 6 Li( 3 He, 3 He 3 He) 3 H and 6 Li( 3 He,t 3 He) 3 He reactions for the symmetric angle pairs 20 0 -20 0 , 28.3 0 -28.3 0 , and 35 0 -35 0 . The theoretical cross sections are calculated in a three-body model where the trions (i.e., mass-3 nuclei) are treated as elementary particles with 6 Li being a 3 He- 3 H bound state. The trion-trion interaction is represented by S wave separable potentials with the breakup cross sections calculated with the tree-body Haftel-Ebenhoeh code. the Coulomb interaction is taken into account by fitting the separable potential parameters to the trion-trion scattering data and is included approximately in the breakup code. The experimental cross sections are compared with both the plane-wave impulse approximation and the three-body model predictions. The plane-wave impulse approximation predicts both the shapes and magnitudes poorly (10 to 20 times experiment). Without Coulomb corrections the three-body model gives good agreement with experiment for the shapes of the spectra with the magnitudes generally being about 40% of experiment for 6 Li( 3 He, 3 He 3 He) 3 H and about 80% for 6 Li( 3 He,t 3 He) 3 He. The Coulomb corrections improve the magnitudes predicted by the three-body model but not the shapes. It is observed that for these reactions S wave separable potentials describe the breakup data much better than they do the two-body trion-trion scattering data. This result should encourage further three-body treatment of these and similar reactions

Mobile Phone Text Messages to Support Treatment Adherence in Adults With High Blood Pressure (SMS-Text Adherence Support [StAR]): A Single-Blind, Randomized Trial.

Science.gov (United States)

Bobrow, Kirsten; Farmer, Andrew J; Springer, David; Shanyinde, Milensu; Yu, Ly-Mee; Brennan, Thomas; Rayner, Brian; Namane, Mosedi; Steyn, Krisela; Tarassenko, Lionel; Levitt, Naomi

2016-02-09

We assessed the effect of automated treatment adherence support delivered via mobile phone short message system (SMS) text messages on blood pressure. In this pragmatic, single-blind, 3-arm, randomized trial (SMS-Text Adherence Support [StAR]) undertaken in South Africa, patients treated for high blood pressure were randomly allocated in a 1:1:1 ratio to information only, interactive SMS text messaging, or usual care. The primary outcome was change in systolic blood pressure at 12 months from baseline measured with a validated oscillometric device. All trial staff were masked to treatment allocation. Analyses were intention to treat. Between June 26, 2012, and November 23, 2012, 1372 participants were randomized to receive information-only SMS text messages (n=457), interactive SMS text messages (n=458), or usual care (n=457). Primary outcome data were available for 1256 participants (92%). At 12 months, the mean adjusted change in systolic blood pressure compared with usual care was -2.2 mm Hg (95% confidence interval, -4.4 to -0.04) with information-only SMS and -1.6 mm Hg (95% confidence interval, -3.7 to 0.6) with interactive SMS. Odds ratios for the proportion of participants with a blood pressure high blood pressure, we found a small reduction in systolic blood pressure control compared with usual care at 12 months. There was no evidence that an interactive intervention increased this effect. URL: http://www.clinicaltrials.gov. Unique identifier: NCT02019823. South African National Clinical Trials Register, number SANCTR DOH-27-1212-386; Pan Africa Trial Register, number PACTR201411000724141. © 2016 American Heart Association, Inc.

Short Text Messages (SMS) as an Additional Tool for Notifying Medical Staff in Case of a Hospital Mass Casualty Incident.

Science.gov (United States)

Timler, Dariusz; Bogusiak, Katarzyna; Kasielska-Trojan, Anna; Neskoromna-Jędrzejczak, Aneta; Gałązkowski, Robert; Szarpak, Łukasz

2016-02-01

The aim of the study was to verify the effectiveness of short text messages (short message service, or SMS) as an additional notification tool in case of fire or a mass casualty incident in a hospital. A total of 2242 SMS text messages were sent to 59 hospital workers divided into 3 groups (n=21, n=19, n=19). Messages were sent from a Samsung GT-S8500 Wave cell phone and Orange Poland was chosen as the telecommunication provider. During a 3-month trial period, messages were sent between 3:35 PM and midnight with no regular pattern. Employees were asked to respond by telling how much time it would take them to reach the hospital in case of a mass casualty incident. The mean reaction time (SMS reply) was 36.41 minutes. The mean declared time of arrival to the hospital was 100.5 minutes. After excluding 10% of extreme values for declared arrival time, the mean arrival time was estimated as 38.35 minutes. Short text messages (SMS) can be considered an additional tool for notifying medical staff in case of a mass casualty incident.

SMS text message reminders to improve infant vaccination coverage in Guatemala: A pilot randomized controlled trial.

Science.gov (United States)

Domek, Gretchen J; Contreras-Roldan, Ingrid L; O'Leary, Sean T; Bull, Sheana; Furniss, Anna; Kempe, Allison; Asturias, Edwin J

2016-05-05

Patient reminder systems are an evidence-based way to improve childhood vaccination rates but are difficult to implement in low- and middle-income countries (LMICs). Short Message Service (SMS) texts may offer a potential low-cost solution, especially in LMICs where mobile phones are becoming more ubiquitous. To determine if an SMS-based vaccination reminder system aimed at improving completion of the infant primary immunization series is feasible and acceptable in Guatemala. A pilot randomized controlled trial was conducted at two public health clinics in Guatemala City. Infants aged 8-14 weeks presenting for the first dose of the primary immunization series were enrolled in March-April 2013. Participants randomized into the intervention received three SMS reminders one week before the second and third dose. A follow-up acceptability survey was administered to both groups. The participation rate was 86.8% (321/370); 8 did not own a cell phone and 12 could not use SMS. 96.9% of intervention parents were sent at least one SMS reminder prior to visit 2 and 96.3% prior to visit 3. Both intervention and usual care participants had high rates of vaccine and visit completion, with a non-statistically significant higher percentage of children in the intervention completing both visit 2 (95.0% vs. 90.1%, p=.12) and visit 3 (84.4% vs. 80.7%, p=.69). More intervention vs. usual care parents agreed that SMS reminders would be helpful for remembering appointments (p<.0001), agreed to being interested in receiving future SMS reminders (p<.0001), and said that they would be willing to pay for future SMS reminders (p=.01). This proof of concept evaluation showed that a new application of SMS technology is feasible to implement in a LMIC with high user satisfaction. Larger studies with modifications in the SMS system are needed to determine effectiveness (Clinical Trial Registry NCT01663636). Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

Relationship Between Teacher ICT Competency And Teacher Acceptance And Use Of School Management System (SMS

Directory of Open Access Journals (Sweden)

Leong Mei Wei

2016-10-01

Full Text Available This study aims at examining the relationship between teacher ICT competency and teacher acceptance and use of SMS in Negeri Sembilan secondary schools in Malaysia. This is a non-experimental quantitative research using survey technique through the administration of a set of questionnaire that comprised teacher demographic variables, teacher ICT competency and teacher acceptance and use of SMS. Some 417 returned questionnaires have been analyzed. The findings showed that teachers in Negeri Sembilan secondary schools rated themselves as having high level of ICT competency, and acceptance and use of SMS. Furthermore, data indicated that there was a statistically significant moderately strong positive correlation between teacher ICT competency and teacher acceptance and use of SMS. In addition, multiple regression analysis showed that smart pedagogy, professional growth and leadership, and digital citizenship were the three teacher ICT competency dimensions that are statistically significant predictors of teacher acceptance and use of SMS. The fitness indexes of the proposed structural model do not achieve the level of fitness required for RMSEA, GFI, and Ratio Chisq/df. Thus, a re-specified structural model was established for this study.

Smithsonian Marine Station (SMS) at Fort Pierce

Science.gov (United States)

share current Smithsonian research on the plants and animals of the Indian River Lagoon and marine Smithsonian Marine Station at Fort Pierce Website Search Box Search Field: SMS Website Search Twitter SMS Home › Welcome to the Smithsonian Marine Station Homepage slideshow Who We Are... The

Mobile Learning Via SMS Among Distance Learners: Does Learning Transfer Occur?

Directory of Open Access Journals (Sweden)

Aznarahayu Ramli

2010-07-01

Full Text Available The purpose of this study is to determine whether learners are willing to transfer learning in this mobile learning environment via SMS. The reason for this is to measure the effectiveness of the new method used in learning and education especially in distance education field. For this reason, students’ responses are gathered which looked at three factors namely learner characteristic, learning design and learning environment. The data are gathered through a survey research design with questionnaires using five-point likert scale. The questionnaires was administered for 105 distance education students from four courses including Bachelor of Science, Bachelor of Arts, Bachelor of Social Science and Bachelor of Management. The Rasch Model Analysis was used to measure these dimensions. Rasch Model is a one-parameter logistic model within item response theory (IRT whereby the amount of a given latent trait in a person and the amount of that same latent trait reflected in various items can be estimated independently yet still compared explicitly to one another. The result of the study showed that learning transfer occurred and being influenced most by learner’s characteristics especially in term of their motivation as well as their perceive utility/value of the SMS learning to their job and academic performances.

Health promotion via SMS improves hypertension knowledge for deaf South Africans

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Hanne Jensen Haricharan

2017-08-01

Full Text Available Abstract Background Signing Deaf South Africans have limited access to health information. As a result, their knowledge about health is limited. Cell phone usage in South Africa is high. This study aimed to assess whether a short message service (SMS-based health promotion campaign could improve Deaf people’s knowledge of hypertension and healthy living. Additionally, the study aimed to assess the acceptability of using SMSs for health promotion targeting Deaf people. Methods A baseline questionnaire assessed participants’ knowledge about hypertension before an SMS-based information campaign was conducted. After the campaign, an exit questionnaire was conducted, containing the same questions as the baseline questionnaire with additional questions about general acceptability and communication preferences. Results were compared between baseline and exit, using McNemar’s test, paired t-test and Wilcoxon signed-rank test. Focus groups aimed to get further information on the impact and acceptability of SMSs. The focus groups were analysed using inductive thematic analysis. Results The campaign recruited 82 participants for the baseline survey, but due to significant loss-to-follow-up and exclusions only 41 participants were included in the analysis of the survey. The majority (60% were men. Eighty percent were employed, while 98% had not finished high school. The campaign showed a statistically significant improvement in overall knowledge about hypertension and healthy living amongst participants. Six individual questions out of 19 also showed a statistically significant improvement. Despite this, participants in focus groups found the medical terminology difficult to understand. Several ways of improving SMS campaigns for the Deaf were identified. These included using using pictures, using ‘signed’ SMSs, combining SMSs with signed drama and linking SMS-campaigns to an interactive communication service that would enable the Deaf to pose

Investigating the impact of SMS speak on the written work of English first language and English second language high school learners

Directory of Open Access Journals (Sweden)

Winzker, Kristy

2009-12-01

Full Text Available This study examined the impact of SMS speak on the written work of English first language (L1 and English second language (L2 grade 8s and 11s. The aim was to establish whether these learners make use of features of SMS speak in their English written work. The participants, 88 learners from an English-Afrikaans dual medium school, completed questionnaires from which the frequency and volume of their SMS use were determined, as well as the features of SMS speak they reportedly use while SMSing. In addition, samples of their English essays were examined for the following features of SMS speak: (deliberate spelling errors; lack of punctuation; over-punctuation; omission of function words; and use of abbreviation, acronyms, emoticons and rebus writing. The questionnaires indicated that these learners are avid users of the SMS. All participants reported using features of SMS speak in their SMSes, and more than 40% reported using SMS speak in their written school work. Despite this, features of SMS speak infrequently occurred in the written work of the learners, which could indicate that the learners are able to assess when it is and is not appropriate to use a certain variety of language. That said, a number of SMS speak features were indeed present in the samples, which indicates that SMS speak had some impact on the written work of these learners. Not all of the nonstandard features of their written English could, however, necessarily be attributed to the influence of SMS speak; specifically some of the spelling and punctuation errors could have occurred in the written English of high school learners from before the advent of cell phones.

Erbium-doped fiber ring laser with SMS modal interferometer for hydrogen sensing

Science.gov (United States)

Zhang, Ya-nan; Zhang, Lebin; Han, Bo; Peng, Huijie; Zhou, Tianmin; Lv, Ri-qing

2018-06-01

A hydrogen sensor based on erbium-doped fiber ring laser with modal interferometer is proposed. A single mode-multimode-single mode (SMS) modal interferometer structure coated with Pd/WO3 film is used as the sensing head, due to that it is easy to be fabricated and low cost. The sensing structure is inserted into an erbium-doped fiber ring laser in order to solve the problem of spectral confusion and improve the detection limit of the hydrogen sensor based on the SMS modal interferometer. The SMS sensing structure is acted as a fiber band-pass filter. When hydrogen concentration around the sensor is changed, it will induce the refractive index and strain variations of the Pd/WO3 film, and then shift the resonant spectrum of the SMS modal interferometer as well as the laser wavelength of the fiber ring laser. Therefore, the hydrogen concentration can be measured by monitoring the wavelength shift of the laser, which has high intensity and narrow full width half maximum. Experimental results demonstrate that the sensor has high sensitivity of 1.23 nm/%, low detection limit of 0.017%, good stability and excellent repeatability.

Teenagers' perceptions of SMS Afrikaans in print advertisements ...

African Journals Online (AJOL)

Teenagers' perceptions of SMS Afrikaans in print advertisements. ... whether SMS Afrikaans could be employed as language of advertising in the print media. ... With regard to the perception of the writer, statistical effects were only found in the ...

A novel approach to imaging extinct seafloor massive sulphides (eSMS) by using ocean bottom seismometer data from the Blue Mining project

Science.gov (United States)

Gil, A.; Chidlow, K. L.; Vardy, M. E.; Bialas, J.; Schroeder, H.; Stobbs, I. J.; Gehrmann, R. A. S.; North, L. J.; Minshull, T. A.; Petersen, S.; Murton, B. J.

2017-12-01

Seafloor massive sulphide (SMS) deposits have generated great interest regarding their formation and composition, since their discovery in 1977. SMS deposits form through hydrothermal circulation and are therefore commonly found near hydrothermal vent sites. The high base (Cu, Zn) and precious metal (Au, Ag) content has interested mining companies, due to their potentially high economic value. Currently, the possibility of mining extinct seafloor massive sulphides (eSMS) deposits has opened a debate about their environmentally and economically sustainable exploitation. A major goal is the rapid exploration and assessment of deposit structure and volume. This is challenging due to their small dimensions (100s m diameter) and typically great water depths (> 3000 mbsl). Here we present a novel approach combining seismic reflection/refraction forward modelling to data acquired from the TAG hydrothermal field (26ºN, Mid-Atlantic Ridge, 3500mbsl) to image deep-water eSMS deposits. In May 2016, the RV METEOR shot 30, short (Mining' project, n˚ 604500.

SMS-Based Learning in Tertiary Education: Achievement and Attitudinal Outcomes

Science.gov (United States)

Katz, Yaacov J.

2013-01-01

SMS delivery platforms are being increasingly used at the university level to enhance student achievement as well as traits and attitudes related to the learning process. SMS delivery provides access to learning materials without being limited by space or time and sophisticated technological advances in SMS delivery have led to enhanced learner…

GSM module for wireless radiation monitoring system via SMS

Science.gov (United States)

Rahman, Nur Aira Abd; Hisyam Ibrahim, Noor; Lombigit, Lojius; Azman, Azraf; Jaafar, Zainudin; Arymaswati Abdullah, Nor; Hadzir Patai Mohamad, Glam

2018-01-01

A customised Global System for Mobile communication (GSM) module is designed for wireless radiation monitoring through Short Messaging Service (SMS). This module is able to receive serial data from radiation monitoring devices such as survey meter or area monitor and transmit the data as text SMS to a host server. It provides two-way communication for data transmission, status query, and configuration setup. The module hardware consists of GSM module, voltage level shifter, SIM circuit and Atmega328P microcontroller. Microcontroller provides control for sending, receiving and AT command processing to GSM module. The firmware is responsible to handle task related to communication between device and host server. It process all incoming SMS, extract, and store new configuration from Host, transmits alert/notification SMS when the radiation data reach/exceed threshold value, and transmits SMS data at every fixed interval according to configuration. Integration of this module with radiation survey/monitoring device will create mobile and wireless radiation monitoring system with prompt emergency alert at high-level radiation.

Mobile phone SMS messages can enhance healthy behaviour: a meta-analysis of randomised controlled trials.

Science.gov (United States)

Orr, Jayne A; King, Robert J

2015-01-01

Healthy behaviour, such as smoking cessation and adherence to prescribed medications, mitigates illness risk factors but health behaviour change can be challenging. Mobile phone short-message service (SMS) messages are increasingly used to deliver interventions designed to enhance healthy behaviour. This meta-analysis used a random-effects model to synthesise 38 randomised controlled trials that investigated the efficacy of SMS messages to enhance healthy behaviour. Participants (N = 19,641) lived in developed and developing countries and were diverse with respect to age, ethnicity, socioeconomic background and health behaviours targeted for change. SMS messages had a small, positive, significant effect (g = 0.291) on a broad range of healthy behaviour. This effect was maximised when multiple SMS messages per day were used (g = 0.395) compared to using lower frequencies (daily, multiple per week and once-off) (g = 0.244). The low heterogeneity in this meta-analysis (I (2) = 38.619) supports reporting a summary effect size and implies that the effect of SMS messaging is robust, regardless of population characteristics or healthy behaviour targeted. SMS messaging is a simple, cost-effective intervention that can be automated and can reach any mobile phone owner. While the effect size is small, potential health benefits are well worth achieving.

Sistem Informasi Penjualan dan Pemesanan Layanan Berbasis Web dan SMS Gateway di Petshop "PetZone"

Directory of Open Access Journals (Sweden)

Siska Fadhilah Wati

2013-09-01

Full Text Available Dewasa ini teknologi informasi sangat membantu dalam dunia bisnis. Kemudahan yang ditawarkan akan menjaring lebih banyak konsumen. Namun, perusahan tingkat menengah seperti PetZone saat ini masih jarang yang menawarkan kemudahan berbelanja atau pemesanan layanan secara online. Oleh karena itu diperlukan sebuah sistem berbasis web di perusahaan PetZone yang dapat memudahkan pemilik dan karyawan dalam apenjualan, pelayanan, dan pemasaran, serta memudahkan pelanggan dalam jual-beli barang dan jasa. Atas dasar masalah tersebut dibangun Sistem Informasi Penjualan dan Pemesanan Layanan Berbasis Web dan SMS Gateway untuk menunjang proses bisnis yang ada. Sistem informasi dibangun menggunakan bahasa pemrograman PHP framework Codeigniter, javascript untuk tampilan yang dinamis, dan database MySQL. Proses pembuatan dan pengembangan Sistem Informasi Penjualan ini menggunakan metode air terjun. Metode air terjun meliputi kebutuhan pengguna, analisis, rancangan, implementasi dan pengujian. Pemodelan Sistem Informasi yang dibangun menggunakan metode berorientasi objek UML (Unified Modeling Language yang terdiri dari Use case  diagram, Class diagram dan Sequence diagram. Hasil pengujian Sistem Informasi Penjualan dan Pemesanan Layanan Berbasis Web dan SMS Gateway menunjukkan bahwa semua fitur yang terdapat baik dalam sistem informasi maupun SMS gateway dapat bekerja dengan baikdengan ratusan sample data, dan server SMS gateway dapat memproses lebih dari satu SMS secara bersamaan. Dalam perkembangan ke depannya nanti, Sistem Informasi Penjualan dan Pemesanan Layanan Berbasis Web dan SMS Gateway masih dapat dikembangkan lagi dengan menambah fitur-fitur pada SMS gateway sehingga lebih memudahkan konsumen.

STS-57 crewmembers train in JSC's FB Shuttle Mission Simulator (SMS)

Science.gov (United States)

1993-01-01

STS-57 Endeavour, Orbiter Vehicle (OV) 105, Mission Specialist 2 (MS2) Nancy J. Sherlock, holding computer diskettes and procedural checklist, discusses equipment operation with Commander Ronald J. Grabe on the middeck of JSC's fixed based (FB) shuttle mission simulator (SMS). Payload Commander (PLC) G. David Low points to a forward locker location as MS3 Peter J.K. Wisoff switches controls on overhead panels MO42F and MO58F, and MS4 Janice E. Voss looks on. The FB-SMS is located in the Mission Simulation and Training Facility Bldg 5.

Dialogizität in der chinesischen und deutschen SMS-Kommunikation – eine kontrastive Studie

Directory of Open Access Journals (Sweden)

Susanne Günthner

2012-01-01

Full Text Available This article presents a dialogical approach to Chinese and German SMS communication. SMS- interactions have frequently been studied from a 'monological point of view', looking at single SMS-messages. In this article, we will develop a dialogically grounded perspective on the interactive dynamics and the social activities constructed in everyday SMS dialogues. Based on SMS data from Chinese and German students, we will argue that - even though production and reception of SMS messages are removed in time and space - SMS communication represents dialogically oriented social activities. Furthermore, as communicative practices, Chinese as well as German SMS-dialogues reveal features of routinization, grounded in technical prerequisites, in the particular writing systems and linguistic conventions as well as in culture specific forms of handling particular social activities.

The Conceptual Idea of Online Social Media Site (SMS) User Account Penetration Testing System

OpenAIRE

Chockalingam, Sabarathinam; Lallie, Harjinder Singh

2014-01-01

Social Media Site (SMS) usage has grown rapidly in the last few years. This sudden increase in SMS usage creates an opportunity for data leakage which could compromise personal and/or professional life. In this work, we have reviewed traditional penetration testing process and discussed the failures of traditional penetration testing process to test the 'People' layer of Simple Enterprise Security Architecture (SESA) model. In order to overcome these failures, we have developed the conceptual...

PENERAPAN CUSTOMER RELATIONSHIP MANAGEMENT (CRM BERBASIS SMS GATEWAY PADA ONLINE SHOP TOKOFARAH

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Arfiani Nur Khusna

2016-01-01

Full Text Available SMS applications has become a promising business opportunities in the consumer and industrial markets in the world. One part that can not be separated from the SMS business is the role of an SMS Gateway, a system used by service providers to send and receive SMS automatically. Online shop tokofarah an online web business venture engaged in the production and sales of baby clothes and children. The problems that exist in the online shop tokofarah is the absence of communication between the customer and tokofarah thus reduced customer loyalty, customers are unaware of the latest promos and discounts, so the application of CRM (Customer Relationship Management is very necessary to help communication. Alternative solutions in addition to implementing CRM also develop and implement SMS technology as a service via SMS Gateway online. Where customers can easily find information on the latest promos and discounts, customers can simply type a certain key word and send it to a specific number that has been provided, the store can also inform customers about the latest promos and products through SMS brodcast. In this study, using Gammu as tools liaison between the device with a computer modem. Making the program using the programming language PHP as an interface, a database maker MySQL tools. The results of the implementation of the concept of SMS Gateway technology is that it can provide convenience for online customers shop tokofarah in knowing the promo and the latest product information and can order via SMS.

PENERAPAN CUSTOMER RELATIONSHIP MANAGEMENT (CRM) BERBASIS SMS GATEWAY PADA ONLINE SHOP TOKOFARAH

OpenAIRE

Arfiani Nur Khusna

2016-01-01

SMS applications has become a promising business opportunities in the consumer and industrial markets in the world. One part that can not be separated from the SMS business is the role of an SMS Gateway, a system used by service providers to send and receive SMS automatically. Online shop tokofarah an online web business venture engaged in the production and sales of baby clothes and children. The problems that exist in the online shop tokofarah is the absence of communication between the cus...

Tungsten phosphanylarylthiolato complexes [W{PhP(2-SC6H4)2-kappa3S,S',P} 2] and [W{P(2-SC6H4)3-kappa4S,S',S",P}2]: synthesis, structures and redox chemistry.

Science.gov (United States)

Hildebrand, Alexandra; Lönnecke, Peter; Silaghi-Dumitrescu, Luminita; Hey-Hawkins, Evamarie

2008-09-14

PhP(2-SHC6H4)2 (PS2H2) reacts with WCl6 with reduction of tungsten to give the air-sensitive tungsten(IV) complex [W{PhP(2-SC6H4)2-kappa(3)S,S',P}2] (1). 1 is oxidised in air to [WO{PhPO(2-SC6H4)2-kappa(3)S,S',O}{PhP(2-SC6H4)2-kappa(3)S,S',P}] (2). The attempted synthesis of 2 by reaction of 1 with iodosobenzene as oxidising agent was unsuccessful. [W{P(2-SC6H4)3-kappa(4)S,S',S",P}2] (3) was formed in the reaction of P(2-SHC6H4)3 (PS3H3) with WCl6. The W(VI) complex 3 contains two PS3(3-) ligands, each coordinated in a tetradentate fashion resulting in a tungsten coordination number of eight. The reaction of 3 with AgBF4 yields the dinuclear tungsten complex [W2{P(2-SC6H4)3-kappa(4)S,S',S",P}3]BF4 (4). Complexes 1-4 were characterised by spectral methods and X-ray structure determination.

SMS service from your GSM mobile phone

CERN Multimedia

IT Department

2009-01-01

The exchange of SMS (Short Message Service) messages is a very popular application of GSM mobile services. However, the use of the application with a CERN subscription is subject to certain conditions: First of all, only text messages can be sent and received with a CERN GSM subscription. These messages are limited to 160 characters. MMS (Multimedia Message Service) messages, which consist in attaching pictures, videos or sounds to a message, are not supported by the current CERN mobile network configuration. In addition, value-added SMS or SMS premium messages (e.g. messages to short numbers involving extra charges) are not permitted. Before sending a message, you must first record the number of the message centre (+41765980000) in your mobile. In principle, this configuration setting is automatically applied to all standard GSM mobile phones when they are issued. To send a message to another GSM user, you must of course enter his or her GSM number. This number must be e...

The mCME Project: A Randomized Controlled Trial of an SMS-Based Continuing Medical Education Intervention for Improving Medical Knowledge among Vietnamese Community Based Physicians' Assistants.

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Christopher J Gill

Full Text Available Community health workers (CHWs provide critical services to underserved populations in low and middle-income countries, but maintaining CHW's clinical knowledge through formal continuing medical education (CME activities is challenging and rarely occurs. We tested whether a Short Message Service (SMS-based mobile CME (mCME intervention could improve medical knowledge among a cadre of Vietnamese CHWs (Community Based Physician's Assistants-CBPAs who are the leading providers of primary medical care for rural underserved populations.The mCME Project was a three arm randomized controlled trial. Group 1 served as controls while Groups 2 and 3 experienced two models of the mCME intervention. Group 2 (passive model participants received a daily SMS bullet point, and were required to reply to the text to acknowledge receipt; Group 3 (interactive model participants received an SMS in multiple choice question format addressing the same thematic area as Group 2, entering an answer (A, B, C or D in their response. The server provided feedback immediately informing the participant whether the answer was correct. Effectiveness was based on standardized examination scores measured at baseline and endline (six months later. Secondary outcomes included job satisfaction and self-efficacy.638 CBPAs were enrolled, randomized, and tested at baseline, with 592 returning at endline (93.7%. Baseline scores were similar across all three groups. Over the next six months, participation of Groups 2 and 3 remained high; they responded to >75% of messages. Group 3 participants answered 43% of the daily SMS questions correctly, but their performance did not improve over time. At endline, the CBPAs reported high satisfaction with the mCME intervention, and deemed the SMS messages highly relevant. However, endline exam scores did not increase over baseline, and did not differ between the three groups. Job satisfaction and self-efficacy scores also did not improve. Average

Identifying clinical course patterns in SMS data using cluster analysis

DEFF Research Database (Denmark)

Kent, Peter; Kongsted, Alice

2012-01-01

ABSTRACT: BACKGROUND: Recently, there has been interest in using the short message service (SMS or text messaging), to gather frequent information on the clinical course of individual patients. One possible role for identifying clinical course patterns is to assist in exploring clinically important...... showed that clinical course patterns can be identified by cluster analysis using all SMS time points as cluster variables. This method is simple, intuitive and does not require a high level of statistical skill. However, there are alternative ways of managing SMS data and many different methods...

Short message service (SMS) applications for disease prevention in developing countries.

Science.gov (United States)

Déglise, Carole; Suggs, L Suzanne; Odermatt, Peter

2012-01-12

The last decade has witnessed unprecedented growth in the number of mobile phones in the developing world, thus linking millions of previously unconnected people. The ubiquity of mobile phones, which allow for short message service (SMS), provides new and innovative opportunities for disease prevention efforts. The aim of this review was to describe the characteristics and outcomes of SMS interventions for disease prevention in developing countries and provide recommendations for future work. A systematic search of peer-reviewed and gray literature was performed for papers published in English, French, and German before May 2011 that describe SMS applications for disease prevention in developing countries. A total of 34 SMS applications were described, among which 5 had findings of an evaluation reported. The majority of SMS applications were pilot projects in various levels of sophistication; nearly all came from gray literature sources. Many applications were initiated by the project with modes of intervention varying between one-way or two-way communication, with or without incentives, and with educative games. Evaluated interventions were well accepted by the beneficiaries. The primary barriers identified were language, timing of messages, mobile network fluctuations, lack of financial incentives, data privacy, and mobile phone turnover. This review illustrates that while many SMS applications for disease prevention exist, few have been evaluated. The dearth of peer-reviewed studies and the limited evidence found in this systematic review highlight the need for high-quality efficacy studies examining behavioral, social, and economic outcomes of SMS applications and mobile phone interventions aimed to promote health in developing country contexts.

Can ‘Mobile Platform’ and ‘Permission Marketing’ dance a tango to the consumers' tune? Modeling adoption of ‘SMS based Permission Advertising’

Directory of Open Access Journals (Sweden)

Prerna Bamoriya

2015-12-01

Full Text Available Many a times situation of advertising clutter is further aggrieved by the markers’ intrusive practices i.e. not asking for consumer’s explicit permission. It results in consumers’ alienation and reduced advertising effectiveness. Solution could be integration of Permission Marketing with an innovative advertising platform like Mobile. This study aimed to develop and validate a comprehensive model for understanding consumers’ adoption behavior towards SMS Based Permission Advertising (SBPA. For this, data was collected using systematic random sampling from 524 respondents and was analyzed using Structural Equation Modeling. Study revealed some critical variables along with complex relationships among such variables, in form of an empirically validated model. At last, study made some important implications for practitioners and researchers.

Congruence between SMS Language and the Standard Persian

Directory of Open Access Journals (Sweden)

Bahman Zandi

2009-07-01

Full Text Available These days cell phone, as the modern instrument has various, cheap, and user-friendly accessories and possibilities. As a result SMS is now one of the most important media used in different situations. In this study, the SMS was analyzed from a linguistic point of view. Using the content analysis method, the grammatical and semantic congruence of the short-messages with standard Persian was examined. Furthermore, the SMS content (quotations, love messages, empathy and greetings, ironies, and jokes and language (Persian, English, Pinglish were studied. For this purpose, 1795 SMSs were received and analyzed during the first half of 2007. The analysis and comparison of the SMSs showed that there is still no specific, uniform language used in their writing. The results showed that though the general tendency is to write in Persian, many SMSs are written in Pinglish.

A conceptual investigation of variables affecting the success and acceptance of SMS Marketing in Iran

OpenAIRE

Adhami, A; Rabiee, A; Adhami, M

2015-01-01

This paper?s aim was to develop a conceptual overview of SMS marketing and delineate factors of new communications technologies on business practice. This study, which was a descriptive survey, was built on primary and secondary data source including a literature review of SMS marketing and a Questionnaire were used as the primary means of collecting secondary data. The sample size of 300 patients was determined according to the Cochran formula. Moreover, data analysis was done in SPSS by usi...

Simion 3D Version 6.0 User`s Manual

Energy Technology Data Exchange (ETDEWEB)

Dahl, D.A.

1995-11-01

The original SIMION was an electrostatic lens analysis and design program developed by D.C. McGilvery at Latrobe University, Bundoora Victoria, Australia, 1977. SIMION for the PC, developed at the Idaho National Engineering Laboratory, shares little more than its name with the original McGilvery version. INEL`s fifth major SIMION release, version 6.0, represents a quantum improvement over previous versions. This C based program can model complex problems using an ion optics workbench that can hold up to 200 2D and/or 3D electrostatic/magnetic potential arrays. Arrays can have up to 10,000,000 points. SIMION 3D`s 32 bit virtual Graphics User Interface provides a highly interactive advanced user environment. All potential arrays are visualized as 3D objects that the user can cut away to inspect ion trajectories and potential energy surfaces. User programs have been greatly extended in versatility and power. A new geometry file option supports the definition of highly complex array geometry. Extensive algorithm modifications have dramatically improved this version`s computational speed and accuracy.

Managing healthcare information using short message service (SMS) in wireless broadband networks

Science.gov (United States)

Documet, Jorge; Tsao, Sinchai; Documet, Luis; Liu, Brent J.; Zhou, Zheng; Joseph, Anika O.

2007-03-01

Due to the ubiquity of cell phones, SMS (Short Message Service) has become an ideal means to wirelessly manage a Healthcare environment and in particular PACS (Picture Archival and Communications System) data. SMS is a flexible and mobile method for real-time access and control of Healthcare information systems such as HIS (Hospital Information System) or PACS. Unlike conventional wireless access methods, SMS' mobility is not limited by the presence of a WiFi network or any other localized signal. It provides a simple, reliable yet flexible method to communicate with an information system. In addition, SMS services are widely available for low costs from cellular phone service providers and allows for more mobility than other services such as wireless internet. This paper aims to describe a use case of SMS as a means of remotely communicating with a PACS server. Remote access to a PACS server and its Query-Retrieve services allows for a more convenient, flexible and streamlined radiology workflow. Wireless access methods such as SMS will increase dedicated PACS workstation availability for more specialized DICOM (Digital Imaging and Communications in Medicine) workflow management. This implementation will address potential security, performance and cost issues of applying SMS as part of a healthcare information management system. This is in an effort to design a wireless communication system with optimal mobility and flexibility at minimum material and time costs.

SMS Language and College Writing :The languages of the College Texters

Directory of Open Access Journals (Sweden)

Norizul Azida Darus

2010-03-01

Full Text Available Many students have become avid texters and are seriously reinventing language to accommodate the 160-character limit of short messages. They are more interested in getting their messages across and thus becoming less concerned about correct spelling, grammar and punctuation. Since texting has become a way of life of many students, it is feared that the SMS language can affect students’ written performance. This research examines the effects of frequent usage of text messaging (SMS on undergraduates academic writing. For the purpose of the study, 264 Diploma students of UiTM Perlis were selected as participants. They were 94 male texters and 170 female texters aged between 18 – 22 years old who were taking three different English courses namely Preparatory English, Mainstream English 1 and Mainstream English 2. The data includes participants’ SMS messages, class assignments and examinations scripts which were analyzed in order to detect the existence of SMS language by using measuring instruments of Orthographic forms (Shortis, 2001. The findings reveal that there were few occurrences of SMS language in students’ examinations scripts among weak students.

Effect of subcutaneous injection of a long-acting analogue of somatostatin (SMS 201-995) on plasma thyroid-stimulating hormone in normal human subjects

Energy Technology Data Exchange (ETDEWEB)

Itoh, S.; Tanaka, K.; Kumagae, M.; Takeda, F.; Morio, K.; Kogure, M.; Hasegawa, M.; Horiuchi, T.; Watabe, T.; Miyabe, S.

1988-01-01

SMS 201-995 (SMS), a synthetic analogue of somatostatin (SRIF) has been shown to be effective in the treatment of the hypersecretion of hormones such as in acromegaly. However, little is known about the effects of SMS on the secretion of thyroid-stimulating hormone (TSH) in normal subjects. In this study, plasma TSH was determined with a highly sensitive immunoradiometric assay, in addition to the concentration of SMS in plasma and urine with a radioimmunoassay, following subcutaneous injection of 25, 50, 100 ..mu..g of SMS or a placebo to normal male subjects, at 0900 h after an overnight fast. The plasma concentrations of SMS were dose-responsive and the peak levels were 1.61 +/- 0.09, 4.91 +/- 0.30 and 8.52 +/- 1.18 ng/ml, which were observed at 30, 15 and 45 min after the injection of 25, 50, and 100 ..mu..g of SMS, respectively. Mean plasma disappearance half-time of SMS was estimated to be 110 +/- 3 min. Plasma TSH was suppressed in a dose dependent manner and the suppression lasted for at least 8 hours. At 8 hours after the injection of 25, 50, and 100 ..mu..g of SMS, the plasma TSH levels were 43.8 +/- 19.4, 33.9 +/- 9.4 and 24.9 +/- 3.2%, respectively, of the basal values.

SMS Security System on Mobile Devices Using Tiny Encryption Algorithm

Science.gov (United States)

Novelan, M. S.; Husein, A. M.; Harahap, M.; Aisyah, S.

2018-04-01

The development of telecommunications technology is so rapid has given such great benefits. With the telecommunication technology, distance and time no longer be a significant obstacle. One of the results of telecommunications technology that is well known is the Short Message Service. In this study developed an application on the mobile phone to modify the SMS message into ciphertext so that the information content of the SMS is not known by others. SMS delivery system for encrypting messages into ciphertext using a key that is entered by the sender then sends to the destination number. SMS reception system to decrypt it to others via SMS without the fear of information from these messages will be known by others. The method used in the system encrypt and decrypt the message is the algorithm Tiny Encryption Algorithm and implemented using the Java programming language. JDK 1.7 as the Java programming language ciphertext into plaintext using the key entered by the receiver and displays the original message to the recipient. This application can be used by someone who wants to send a confidential information and the Java compiler. Eclipse, a Java SDK and the Android SDK as a Java source code editor.

A Review of Text Messaging (SMS) as a Communication Tool for Higher Education

OpenAIRE

Dr.Daragh Naughton

2014-01-01

Since 2011, The Limerick Institute of Technology (School of Applied Science Engineering & Technology) has actively engaged in a course of research to determine if SMS can be used to (1) increase student’s preparation for class, (2) increase their motivational levels towards learning and (3) to assist with memory retention. The purpose of this paper is to introduce the concept of the technology and to summarise the academic arguments that have been made both for and against the use of such tec...

Perancangan Dan Realisasi Sistem Transmisi Data GPS Menggunakan Teknologi SMS (Short Messaging Service Sebagai Aplikasi Sistem Personal Tracking

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DECY NATALIANA

2017-06-01

Full Text Available Abstrak Berprinsip pada pengembangan teknologi dan aplikasi dari sistem penjejakan posisi (tracking, maka dibuatlah sistem personal tracking dengan mentransmisikan data GPS (Global Positioning System dengan menggunakan teknologi SMS (Short Messaging Service pada jaringan GSM (Global System for Mobile Communications sebagai media transmisinya.  Dengan sistem GPS akan diperoleh data garis lintang, serta garis bujur dari GPS receiver.  Data tersebut akan diteruskan oleh mikrokontroler untuk dikirim ke ponsel pengamat melalui komunikasi SMS.  Hasil pengujian menunjukkan bahwa device personal tracking berhasil mengirimkan data berupa IMEI, Tanggal satelit, waktu satelit, koordinat longitude, koordinat latitude, dan jumlah satelit yang berhasil ditangkap oleh device ke ponsel pengamat.  Dari data koordinat tersebut pengamat dapat memantau posisi device personal tracking berada dengan bantuan aplikasi pendukung yaitu Google Maps. Kata kunci: GPS, Personal Tracking, SMS, Google Maps.   Abstract Base on technology and application development of tracking, personal tracking system was made by transmiting GPS (Global Positioning System data using SMS (Short Messaging Service technology with GSM (Global System for Mobile Communications network as transmitter media.  BY GPS system, we can get datas such as latitude and longitude of GPS receiver.  Those datas will be processed by microcontroller to be sent from GSM/GPRS module to user cellular phone through SMS communication.  The test result showed that the device can be sending datas such as IMEI, UTC date, UTC time, longitude coordinate, latitude coordinate, and number sattelite which detected by device to user’s phonecell.  From those coordinate, user can be monitoring the device’s position with the Google Maps application. Keywords: GPS, Personal Tracking, SMS, Google Maps.

23 CFR 972.212 - Federal lands safety management system (SMS).

Science.gov (United States)

2010-04-01

... safety is considered and implemented as appropriate in all phases of transportation system planning... basic framework for a SMS: (1) An ongoing program for the collection, maintenance and reporting of a... correct the identified hazards and potential hazards. (3) A process for communication, coordination, and...

Rational design and enantioselective synthesis of (1R,4S,5R,6S)-3-azabicyclo[3.3.0]octane-4,6-dicarboxylic acid - a novel inhibitor at human glutamate transporter subtypes 1, 2, and 3

DEFF Research Database (Denmark)

Bunch, Lennart; Nielsen, Birgitte; Jensen, Anders A.

2006-01-01

The natural product kainic acid is used as template for the rational design of a novel conformationally restricted (S)-glutamic acid (Glu) analogue, (1R,4S,5R,6S)-3-azabicyclo[3.3.0]octane-4,6-dicarboxylic acid (1a). The target structure 1a was synthesized from commercially available (S)-pyroglut......The natural product kainic acid is used as template for the rational design of a novel conformationally restricted (S)-glutamic acid (Glu) analogue, (1R,4S,5R,6S)-3-azabicyclo[3.3.0]octane-4,6-dicarboxylic acid (1a). The target structure 1a was synthesized from commercially available (S...

The use of GPS and SMS data in illuminating the Mobility of Families

DEFF Research Database (Denmark)

Reinau, Kristian Hegner; Harder, Henrik

, and these are for example how complex questions the respondents can answer through SMS's and how respondents can be motivated to send SMS's during their daily routines. This methodological discussion of the strengths and weaknesses of the combination of GPS data and SMS data in this paper is of value to all researchers...

Analisis & Perumusan Fitur Aplikasi Sms-marketing Berdasarkan Customer Relationship Management Model

OpenAIRE

Wijaya, Sidiq Wahyu Surya; Laksito, Arif Dwi

2015-01-01

The growth of Micro, Small and Medium Enterprises (UMKM) in Indonesia is very rapid. However, in terms of Customer Relationship Management, it is still few of UMKM which actually implement it. In fact, it can ensure that all customers have/use a mobile phone, either a normal mobile phone or smartphone, which should be used for the purposes of customer relationship management (Customer Relationship Management). One of these is the use of SMS (Short Message Services) technplogy. Therefore, in ...

Evaluation of SMS reminder messages for altering treatment adherence and health seeking perceptions among malaria care-seekers in Nigeria.

Science.gov (United States)

Liu, Jenny X; Modrek, Sepideh

2016-12-01

In Nigeria, access to malaria diagnostics may be expanded if drug retailers were allowed to administer malaria rapid diagnostic tests (RDTs). A 2012 pilot intervention showed that short message service (SMS) reminder messages could boost treatment adherence to RDT results by 10-14% points. This study aimed to replicate the SMS intervention in a different population, and additionally test the effect of an expanded message about anticipated RDT access policy change on customers' acceptability for drug retailers' administration of RDTs. One day after being tested with an RDT, participants who purchased malaria treatment from drug shops were randomized to receive (1) a basic SMS reminder repeating the RDT result and appropriate treatment actions, (2) an expanded SMS reminder additionally saying that the 'government might allow pharmacists/chemists to do RDTs' or (3) no SMS reminders (i.e. control). Using regression analysis, we estimate intent-to-treat (ITT) and treatment effects on the treated for 686 study participants. Results corroborate previous findings that a basic SMS reminder increased treatment adherence [odds ratio (OR) = 1.53, 95% CI 0.96-2.44] and decreased use of unnecessary anti-malarials for RDT-negative adults [OR = 0.63, 95% CI 0.39-1.00]. The expanded SMS also increased adherence for adults [OR = 1.42, 95% CI 0.97-2.07], but the effects for sick children differed-the basic SMS did not have any measurable impact on treatment adherence [OR = 0.87, 95% CI 0.24-3.09] or use of unnecessary anti-malarials [OR = 1.27, 95% CI 0.32-1.93], and the expanded SMS actually led to poorer treatment adherence [OR = 0.26, 95% CI 0.10-0.66] and increased use of unnecessary anti-malarials [OR = 4.67, 95% CI 1.76-12.43]. Further, the targeted but neutral message in the expanded SMS lowered acceptance for drug retailers' administration of RDTs [OR = 0.55, 95% CI 0.10-2.93], counter to what we hypothesized. Future SMS interventions should

Manipulative Use of Short Messaging Service (SMS Text Messages by Nigerian Telecommunications Companies

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Ayoola, Kehinde A.

2014-02-01

Full Text Available This paper is an application of Relevance Theory for the interpretation of short messaging service (SMS text messages emanating from Nigerian telecommunications companies to their subscribers. The aim of the research was to identify and describe the manipulative strategies employed by Nigerian telecommunications companies to induce subscribers to part with their money through sales promotion lotteries. 100 SMS texts were purposively extracted from the cell phones of randomly selected residents of Lagos Nigeria who had received promotional SMS text messages from three major Nigerian telecommunications companies. Using Sperber and Wilson's Relevance Theory (1995 as its theoretical framework, the paper described the manipulative use of SMS by Nigerian telecommunications companies. The analysis revealed that SMS text messages were encoded to achieve maximization of relevance through explicature and implicature; contextual implication and strengthening; and the reduction of processing effort through violating the maxim of truthfulness and the creative use of graphology. The paper concludes that SMS text-messages were used manipulatively by Nigerian telecommunications companies to earn indirect income from sales promotion lottery.

Comparison between data obtained through real-time data capture by SMS and a retrospective telephone interview

DEFF Research Database (Denmark)

Johansen, Bendt; Wedderkopp, Niels

2010-01-01

BACKGROUND: The aims of the current study were: a) to quantitatively compare data obtained by Short Message Service (SMS) with data from a telephone interview, b) to investigate whether the respondents had found it acceptable to answer the weekly two SMS questions, c) to explore whether....... Bland-Altman limits of agreement were calculated. The two quantitative questions were reported as percentages. Actual costs for the SMS-Track-Questionnaire (SMS-T-Q) were compared with estimated costs for paper version surveys. RESULTS: There was high agreement between telephone interview and SMS...... an additional weekly third SMS question would have been acceptable, and d) to calculate the total cost of using the SMS technology. METHODS: SMS technology was used each week for 53 weeks to monitor 260 patients with low back pain (LBP) in a clinical study. Each week, these patients were asked the same two...

Vertical Cable Seismic Survey for SMS exploration

Science.gov (United States)

Asakawa, Eiichi; Murakami, Fumitoshi; Tsukahara, Hotoshi; Mizohata, Shigeharu

2014-05-01

The Vertical Cable Seismic (VCS) survey is one of the reflection seismic methods. It uses hydrophone arrays vertically moored from the seafloor to record acoustic waves generated by sea-surface, deep-towed or ocean bottom sources. Analyzing the reflections from the sub-seabed, we could look into the subsurface structure. Because the VCS is an efficient high-resolution 3D seismic survey method for a spatially-bounded area, we proposed it for the SMS survey tool development program that the Ministry of Education, Culture, Sports, Science and Technology (MEXT) started in 2009. We have been developing the VCS survey system, including not only data acquisition hardware but data processing and analysis technique. We carried out several VCS surveys combining with surface towed source, deep towed source and ocean bottom source. The water depths of these surveys are from 100m up to 2100 m. Through these experiments, our VCS data acquisition system has been also completed. But the data processing techniques are still on the way. One of the most critical issues is the positioning in the water. The uncertainty in the positions of the source and of the hydrophones in water degraded the quality of subsurface image. GPS navigation system is available on sea surface, but in case of deep-towed source or ocean bottom source, the accuracy of shot position with SSBL/USBL is not sufficient for the very high-resolution imaging. We have developed a new approach to determine the positions in water using the travel time data from the source to VCS hydrophones. In 2013, we have carried out the second VCS survey using the surface-towed high-voltage sparker and ocean bottom source in the Izena Cauldron, which is one of the most promising SMS areas around Japan. The positions of ocean bottom source estimated by this method are consistent with the VCS field records. The VCS data with the sparker have been processed with 3D PSTM. It gives the very high resolution 3D volume deeper than two

STS-30 crewmembers pose for informal portrait on JSC FB-SMS middeck

Science.gov (United States)

1988-01-01

STS-30 Atlantis, Orbiter Vehicle (OV) 104, crewmembers pause briefly from their training schedule to pose for informal portrait in JSC fixed base (FB) shuttle mission simulator (SMS). On FB-SMS middeck are (left to right) Commander David M. Walker, Mission Specialist (MS) Mark C. Lee, MS Mary L. Cleave, Pilot Ronald J. Grabe, and MS Norman E. Thagard. FB-SMS is located in JSC's Mission Simulation and Training Facility Bldg 5.

Prototipe sistem peringatan dini berbasis SMS untuk mendeteksi kenaikan kadar gas amoniak di pengolahan air limbah industri penyamakan kulit

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Wahyu Pradana Arsitika

2013-06-01

Full Text Available The objective of this research was to produce prototype of an early warning system based on SMS for detection the rising level of ammonia gas in wastewater treatment of leather tanning industry. The systems consist of three parts, those were data input, data processing, and output. Ammonia gas sensor as a detector that produces an analog Direct Current (DC voltage. Analog to Digital Converter (ADC pin on the microcontroller received an analog DC voltage to be processed. ADC readings done through the Liquid Crystal Display (LCD while the Global System for Mobile Communications (GSM modem was used to send Short Massage Service (SMS. This early warning system worked by determining a threshold value. SMS would be sent to hand phone number of job holder, if the ADC value exceeded the specified threshold value. Result obtained was the ammonia gas sensor model are MQ137 based on SnO , Arduino Uno as 2 microcontroller module based on Atmega 328P microcontroller, and General Packet Radio Service (GPRS Shield as GSM modem that compatible with the Arduino Uno R3 pin.

The effect of feedback by SMS-text messages and email on household electricity consumption

DEFF Research Database (Denmark)

Gleerup, Maria; Larsen, Anders; Leth-Petersen, Søren

2010-01-01

This paper analyzes the effect of supplying feedback by text messages (SMS) and email about electricity consumption on the level of total household electricity consumption. An experiment was conducted in which 1,452 households were randomly allocated to three experimental groups and two control....... Results suggest that email and SMS messaging that communicated timely information about a household's 'exceptional' consumption periods (e.g. highest week of electricity use in past quarter) produced average reductions in total annual electricity use of about 3%. The feedback technology is cheap...

Accelerating magnetic resonance fingerprinting (MRF) using t-blipped simultaneous multislice (SMS) acquisition.

Science.gov (United States)

Ye, Huihui; Ma, Dan; Jiang, Yun; Cauley, Stephen F; Du, Yiping; Wald, Lawrence L; Griswold, Mark A; Setsompop, Kawin

2016-05-01

We incorporate simultaneous multislice (SMS) acquisition into MR fingerprinting (MRF) to accelerate the MRF acquisition. The t-Blipped SMS-MRF method is achieved by adding a Gz blip before each data acquisition window and balancing it with a Gz blip of opposing polarity at the end of each TR. Thus the signal from different simultaneously excited slices are encoded with different phases without disturbing the signal evolution. Furthermore, by varying the Gz blip area and/or polarity as a function of repetition time, the slices' differential phase can also be made to vary as a function of time. For reconstruction of t-Blipped SMS-MRF data, we demonstrate a combined slice-direction SENSE and modified dictionary matching method. In Monte Carlo simulation, the parameter mapping from multiband factor (MB) = 2 t-Blipped SMS-MRF shows good accuracy and precision when compared with results from reference conventional MRF data with concordance correlation coefficients (CCC) of 0.96 for T1 estimates and 0.90 for T2 estimates. For in vivo experiments, T1 and T2 maps from MB=2 t-Blipped SMS-MRF have a high agreement with ones from conventional MRF. The MB=2 t-Blipped SMS-MRF acquisition/reconstruction method has been demonstrated and validated to provide more rapid parameter mapping in the MRF framework. © 2015 Wiley Periodicals, Inc.

Comparison between data obtained through real-time data capture by SMS and a retrospective telephone interview

OpenAIRE

Johansen, Bendt; Wedderkopp, Niels

2010-01-01

Abstract Background The aims of the current study were: a) to quantitatively compare data obtained by Short Message Service (SMS) with data from a telephone interview, b) to investigate whether the respondents had found it acceptable to answer the weekly two SMS questions, c) to explore whether an additional weekly third SMS question would have been acceptable, and d) to calculate the total cost of using the SMS technology. Methods SMS technology was used each week for 53 weeks to monitor 260...

Relationship between the spatial distribution of SMS messages reporting needs and building damage in 2010 Haiti disaster

Directory of Open Access Journals (Sweden)

C. Corbane

2012-02-01

Full Text Available Just 4 days after the M = 7.1 earthquake on 12 January 2010, Haitians could send SMS messages about their location and urgent needs through the on-line mapping platform Ushahidi. This real-time crowdsourcing of crisis information provided direct support to key humanitarian resources on the ground, including Search and Rescue teams. In addition to its use as a knowledge base for rescue operations and aid provision, the spatial distribution of geolocated SMS messages may represent an early indicator on the spatial distribution and on the intensity of building damage.

This work explores the relationship between the spatial patterns of SMS messages and building damage. The latter is derived from the detailed damage assessment of individual buildings interpreted in post-earthquake airborne photos. The interaction between SMS messages and building damage is studied by analyzing the spatial structure of the corresponding bivariate patterns.

The analysis is performed through the implementation of cross Ripley's K-function which is suitable for characterizing the spatial structure of a bivariate pattern, and more precisely the spatial relationship between two types of point sets located in the same study area.

The results show a strong attraction between the patterns exhibited by SMS messages and building damages. The interactions identified between the two patterns suggest that the geolocated SMS can be used as early indicators of the spatial distribution of building damage pattern. Accordingly, a statistical model has been developed to map the distribution of building damage from the geolocated SMS pattern.

The study presented in this paper is the first attempt to derive quantitative estimates on the spatial patterns of novel crowdsourced information and correlate these to established methods in damage assessment using remote sensing data. The consequences of the study findings for rapid damage detection in

The Use of Mobile Apps and SMS Messaging as Physical and Mental Health Interventions: Systematic Review.

Science.gov (United States)

Rathbone, Amy Leigh; Prescott, Julie

2017-08-24

studies, inclusive of 4658 participants were reviewed. The papers included randomized controlled trials (RCTs) (n=19), within-group studies (n=7), and 1 within-group study with qualitative aspect. Studies show improvement in physical health and significant reductions of anxiety, stress, and depression. Within-group and between-group effect sizes ranged from 0.05-3.37 (immediately posttest), 0.05-3.25 (1-month follow-up), 0.08-3.08 (2-month follow-up), 0.00-3.10 (3-month follow-up), and 0.02-0.27 (6-month follow-up). Usability and feasibility of mHealth interventions, where reported, also gave promising, significant results. The review shows the promising and emerging efficacy of using mobile apps and SMS text messaging as mHealth interventions. ©Amy Leigh Rathbone, Julie Prescott. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 24.08.2017.

Excessive grooming induced by somatostatin or its analog SMS 201-995

NARCIS (Netherlands)

Wimersma Greidanus, T.B. van; Maigret, C.; Krechting, B.

1987-01-01

Intracerebroventricular (i.c.v.) administration of somatostatin or SMS 201-995 induces excessive grooming behavior in rats. The grooming inducing effect of somatostatin is rather weak, as doses of 300 ng or less did not result in increased total grooming scores. In contrast a dose of 10 ng SMS

Photocatalytic activity of Bi_2WO_6/Bi_2S_3 heterojunctions: the facilitation of exposed facets of Bi_2WO_6 substrate

International Nuclear Information System (INIS)

Yan, Long; Wang, Yufei; Shen, Huidong; Zhang, Yu; Li, Jian; Wang, Danjun

2017-01-01

Highlights: • Bi_2S_3/Bi_2WO_6 hybrids with exposed (020) Bi_2WO_6 facets have been synthesized. • X-ray photoelectron spectroscopy reveals that a small amount of Bi_2S_3 was formed. • The enhanced photoactivity of hybrids is due to heterojunction and (020) facets. • A possible photocatalytic degradation mechanism is proposed. - Abstract: Bi_2S_3/Bi_2WO_6 hybrid architectures with exposed (020) Bi_2WO_6 facets have been synthesized via a controlled anion exchange approach. X-ray photoelectron spectroscopy (XPS) reveals that a small amount of Bi_2S_3 was formed on the surface of Bi_2WO_6 during the anion exchange process, thus leading to the transformation from the Bi_2WO_6 to Bi_2S_3/Bi_2WO_6. A rhodamine B (RhB) aqueous solution was chosen as model organic pollutants to evaluate the photocatalytic activities of the Bi_2S_3/Bi_2WO_6 catalysts. Under visible light irradiation, the Bi_2S_3/Bi_2WO_6-TAA displayed the excellent visible light photoactivities compared with pure Bi_2S_3, Bi_2WO_6 and other composite photocatalysts. The efficient photocatalytic activity of the Bi_2S_3/Bi_2WO_6-TAA composite microspheres was ascribed to the constructed heterojunctions and the inner electric field caused by the exposed (020) Bi_2WO_6 facets. Active species trapping experiments revealed that h"+ and O_2·"− are the main active species in the photocatalytic process. Furthermore, the as-obtained photocatalysts showed good photocatalytic activity after four recycles. The results presented in this study provide a new concept for the rational design and development of highly efficient photocatalysts.

Varietäten und Sprachkontakt in rätoromanischen SMS

Directory of Open Access Journals (Sweden)

Grünert, Matthias

2011-01-01

Full Text Available As a minority language in Switzerland, the Romansh of the Grisons is exposed to pressure from the dominant language in its region, namely (Swiss German. Consequently, it has not developed a generally accepted standardized written form, being above all a spoken language, which cedes many written functions to the dominant language. These premises entail a complex spectrum of language variation in informal written use of Romansh in SMS-communication. This variation includes deviations from regional written norms, traits of (dialectal orality, interference of (Swiss German, and code-switching to (Swiss German. Language contact is evident in the fact that Romansh is used for part of an SMS whereas another part of the same SMS sent by the same person may be written in one or even in two varieties of the majority language, i.e. German and Swiss German. Some speakers of Romansh, mainly people who live outside of the traditional linguistic territory, do not write in Romansh at all. It should be noted that the users of Romansh in SMS-communication who participated in this research project are mainly women with university-level educations who are working in the tertiary sector.

DESAIN DAN IMPLEMENTASI SISTEM KENDALI INTENSITAS CAHAYA PPR MENGGUNAKAN SMS BERBASIS REMOTE CONTROL

Directory of Open Access Journals (Sweden)

Mohammad Khairuddin

2015-06-01

Full Text Available Makalah ini membahas kendali jarak jauh intensitas cahaya piranti penerangan ruang (PPR secara efisien menggunakan short message service (SMS berbasis remote control. Dengan sistem kendali berbasis SMS sebagai remote control maka semua PPR dapat dikendalikan dari manapun di seluruh penjuru tanah air dengan syarat tempat tersebut terjangkau oleh sinyal telekomunikasi yang disediakan oleh provider. Sistem ini didesain untuk memenuhi arahan hemat energi oleh Kementerian Energi dan Pertambangan. Sistem kendali intensitas cahaya PPR menggunakan SMS berbasis remote control ini sebagai terobosan sistem saklar manual yang selama ini dibatasi oleh ruang secara fisik. Kemudahan penggunaan handphone (HP telah menjadi peluang bagi sistem saklar PPR. Didukung dengan semakin murahnya biaya berkomunikasi melalui SMS. Peluang ini mendukung kemudahan pengguna HP dengan menambah fitur sistem kendali intensitas cahaya PPR menggunakan SMS berbasis remote control. Sistem kendali jarak jauh menggunakan server modem wavecom fastrack supreme. Sistem ini menggunakan prosesor ATmega8 dengan interfacing menggunakan RS232. Hasil eksperimen menunjukan bahwa tidak ada perbedaan waktu terhadap variabel jarak posisi PPR dengan HP pengirim SMS selaku comander untuk eksekusi pengaturan intensitas cahaya. Dengan rerata waktu jeda 4,38 detik. Semakin besar prosentase sudut pemicuan TRIAC maka akan semakin besar nilai intensitas cahaya. Tidak ada perbedaan signifikan terhadap lama waktu hasil eksekusi terhadap variasi provider yang digunakan.

Sistem Pengamanan Pintu Rumah Otomatis via SMS Berbasis Mikrokontroller ATMega328P

Directory of Open Access Journals (Sweden)

Muhammad Ridwan Asad

2015-01-01

Full Text Available In this final project was designed an automatic door security used SMS, which is serves as security for a microcontroller based door. This system was designed to facilitate the home user to lock the door and notice the condition of the house when the doors was left empty. The medium used is a phone by using SMS facility. This device consists of a sensor that is a “push button” that serves as input to inform the condition of the door to the microcontroller, microcontroller used is ATmega328P. Then Wavecom GSM Modem M1306B which serves as the sender and recipient SMS, using a solenoid to lock the door, and use the buzzer for alarm. The security system has been built with the working principles if there are people who want to try to enter and then numbers uninitialized on the microcontroller, the system will give a warning SMS notification to the user that "THERE ARE TRYING SIGN", and when the system is forcibly opened, the system will activate alarm as a warning sign and send SMS alert notification text of "alarm" to the phone number programmed into microntroller.

Comparison between data obtained through real-time data capture by SMS and a retrospective telephone interview.

Science.gov (United States)

Johansen, Bendt; Wedderkopp, Niels

2010-05-26

The aims of the current study were: a) to quantitatively compare data obtained by Short Message Service (SMS) with data from a telephone interview, b) to investigate whether the respondents had found it acceptable to answer the weekly two SMS questions, c) to explore whether an additional weekly third SMS question would have been acceptable, and d) to calculate the total cost of using the SMS technology. SMS technology was used each week for 53 weeks to monitor 260 patients with low back pain (LBP) in a clinical study. Each week, these patients were asked the same two questions: "How many days in the past week have you had problems due to LBP?" and "How many days in the past week have you been off work due to LBP problems?" The last 31 patients were also contacted by telephone 53 weeks after recruitment and asked to recall the number of days with LBP problems and days off work for the a) past week, b) past month, and c) past year. The two sets of answers to the same questions for these patients were compared. Patients were also asked whether a third SMS question would have been acceptable. The test-retest reliability was compared for 1-week, 1-month, and 1-year. Bland-Altman limits of agreement were calculated. The two quantitative questions were reported as percentages. Actual costs for the SMS-Track-Questionnaire (SMS-T-Q) were compared with estimated costs for paper version surveys. There was high agreement between telephone interview and SMS-T-Q responses for the 1-week and 1-month recall. In contrast, the 1-year recall showed very low agreement. A third SMS question would have been acceptable. The SMS system was considerably less costly than a paper-based survey, beyond a certain threshold number of questionnaires. SMS-T-Q appears to be a cheaper and better method to collect reliable LBP data than paper-based surveys.

Lay persons alerted by mobile application system initiate earlier cardio-pulmonary resuscitation: A comparison with SMS-based system notification.

Science.gov (United States)

Caputo, Maria Luce; Muschietti, Sandro; Burkart, Roman; Benvenuti, Claudio; Conte, Giulio; Regoli, François; Mauri, Romano; Klersy, Catherine; Moccetti, Tiziano; Auricchio, Angelo

2017-05-01

We compared the time to initiation of cardiopulmonary resuscitation (CPR) by lay responders and/or first responders alerted either via Short Message Service (SMS) or by using a mobile application-based alert system (APP). The Ticino Registry of Cardiac Arrest collects all data about out-of-hospital cardiac arrests (OHCAs) occurring in the Canton of Ticino. At the time of a bystander's call, the EMS dispatcher sends one ambulance and alerts the first-responders network made up of police officers or fire brigade equipped with an automatic external defibrillator, the so called "traditional" first responders, and - if the scene was considered safe - lay responders as well. We evaluated the time from call to arrival of traditional first responders and/or lay responders when alerted either via SMS or the new developed mobile APP. Over the study period 593 OHCAs have occurred. Notification to the first responders network was sent via SMS in 198 cases and via mobile APP in 134 cases. Median time to first responder/lay responder arrival on scene was significantly reduced by the APP-based system (3.5 [2.8-5.2]) compared to the SMS-based system (5.6 [4.2-8.5] min, p 0.0001). The proportion of lay responders arriving first on the scene significantly increased (70% vs. 15%, play responder determined a higher survival rate. The mobile APP system is highly efficient in the recruitment of first responders, significantly reducing the time to the initiation of CPR thus increasing survival rates. Copyright © 2017 The Authors. Published by Elsevier B.V. All rights reserved.

The Effect of Bilingualism on Communication Efficiency in Text Messages (SMS)

Science.gov (United States)

Carrier, L. Mark; Benitez, Sandra Y.

2010-01-01

The widespread use of cell phones has led to the proliferation of messages sent using the Short Messaging Service (SMS). The 160-character limit on text messages encourages the use of shortenings and other shortcuts in language use. When bilingual speakers use SMS, their access to multiple sources of vocabulary, sentence structure, and other…

Short message service (SMS language and written language skills: educators' perspectives

Directory of Open Access Journals (Sweden)

Salomé Geertsema

2011-01-01

Full Text Available SMS language is English language slang, used as a means of mobile phone text messaging. This practice may impact on the written language skills of learners at school. The main aim of this study was to determine the perspectives of Grade 8 and 9 English (as Home Language educators in Gauteng regarding the possible influence of SMS language on certain aspects of learners' written language skills. If an influence was perceived by the educators, their perceptions regarding the degree and nature of the influence were also explored. A quantitative research design, utilising a questionnaire, was employed. The sample of participants comprised 22 educators employed at independent secondaryschools within Gauteng, South Africa. The results indicated that the majority of educators viewed SMS language as having a negative influence on the written language skills of Grade 8 and 9 learners. The influence was perceived as occurring in the learners' spelling, punctuation, and sentence length. A further finding was that the majority of educators address the negative influences of SMS language when encountered in written tasks.

SMS marketing: It's place in mobile commerce and opportunity in the South African market

Directory of Open Access Journals (Sweden)

Frik Jansen van Ryssen

2004-12-01

Full Text Available This article investigates Short Message Service (SMS Marketing's place in the world of mobile commerce (m-commerce. The article also investigates the opportunity that SMS Marketing presents in the South African market. The article indicates a couple of clear guidelines and implications for marketers on how to approach the challenge presented by technological advances that allowed this new trend of mass- and personalised marketing messages via SMS. Advances in the m-commerce field are predicted, and an indication of the proposed target market is provided. Of these devices, the cellphone is the most relevant to the article, because it is the main vehicle through with SMS's are sent and received. It is concluded that SMS Marketing requires a great amount of investigation by every marketer and that continuous monitoring will be required in order for companies not to fall behind or be caught napping by competitors.

Validity of the SMS, Phone, and medical staff Examination sports injury surveillance system for time-loss and medical attention injuries in sports.

Science.gov (United States)

Møller, M; Wedderkopp, N; Myklebust, G; Lind, M; Sørensen, H; Hebert, J J; Emery, C A; Attermann, J

2018-01-01

The accurate measurement of sport exposure time and injury occurrence is key to effective injury prevention and management. Current measures are limited by their inability to identify all types of sport-related injury, narrow scope of injury information, or lack the perspective of the injured athlete. The aims of the study were to evaluate the proportion of injuries and the agreement between sport exposures reported by the SMS messaging and follow-up telephone part of the SMS, Phone, and medical staff Examination (SPEx) sports injury surveillance system when compared to measures obtained by trained on-field observers and medical staff (comparison method). We followed 24 elite adolescent handball players over 12 consecutive weeks. Eighty-six injury registrations were obtained by the SPEx and comparison methods. Of them, 35 injury registrations (41%) were captured by SPEx only, 10 injury registrations (12%) by the comparison method only, and 41 injury registrations (48%) by both methods. Weekly exposure time differences (95% limits of agreement) between SPEx and the comparison method ranged from -4.2 to 6.3 hours (training) and -1.5 to 1.0 hours (match) with systematic differences being 1.1 hours (95% CI 0.7 to 1.4) and -0.2 (95% CI -0.3 to -0.2), respectively. These results support the ability of the SPEx system to measure training and match exposures and injury occurrence among young athletes. High weekly response proportions (mean 83%) indicate that SMS messaging can be used for player measures of injury consequences beyond time-loss from sport. However, this needs to be further evaluated in large-scale studies. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Accelerating Magnetic Resonance Fingerprinting (MRF) using t-Blipped Simultaneous Multi-Slice (SMS) acquisition

Science.gov (United States)

Ye, Huihui; Ma, Dan; Jiang, Yun; Cauley, Stephen F.; Du, Yiping; Wald, Lawrence L.; Griswold, Mark A.; Setsompop, Kawin

2015-01-01

Purpose We incorporate Simultaneous Multi-Slice (SMS) acquisition into MR Fingerprinting (MRF) to accelerate the MRF acquisition. Methods The t-Blipped SMS-MRF method is achieved by adding a Gz blip before each data acquisition window and balancing it with a Gz blip of opposing polarity at the end of each TR. Thus the signal from different simultaneously excited slices are encoded with different phases without disturbing the signal evolution. Further, by varying the Gz blip area and/or polarity as a function of TR, the slices’ differential phase can also be made to vary as a function of time. For reconstruction of t-Blipped SMS-MRF data, we demonstrate a combined slice-direction SENSE and modified dictionary matching method. Results In Monte Carlo simulation, the parameter mapping from Multi-band factor (MB)=2 t-Blipped SMS-MRF shows good accuracy and precision when compared to results from reference conventional MRF data with concordance correlation coefficients (CCC) of 0.96 for T1 estimates and 0.90 for T2 estimates. For in vivo experiments, T1 and T2 maps from MB=2 t-Blipped SMS-MRF have a high agreement with ones from conventional MRF. Conclusions The MB=2 t-Blipped SMS-MRF acquisition/reconstruction method has been demonstrated and validated to provide more rapid parameter mapping in the MRF framework. PMID:26059430

Short Message Service (SMS) Language and Written Language Skills: Educators' Perspectives

Science.gov (United States)

Geertsema, Salomé; Hyman, Charene; van Deventer, Chantelle

2011-01-01

SMS language is English language slang, used as a means of mobile phone text messaging. This practice may impact on the written language skills of learners at school. The main aim of this study was to determine the perspectives of Grade 8 and 9 English (as Home Language) educators in Gauteng regarding the possible influence of SMS language on…

A Comparative Study with RapidMiner and WEKA Tools over some Classification Techniques for SMS Spam

Science.gov (United States)

Foozy, Cik Feresa Mohd; Ahmad, Rabiah; Faizal Abdollah, M. A.; Chai Wen, Chuah

2017-08-01

SMS Spamming is a serious attack that can manipulate the use of the SMS by spreading the advertisement in bulk. By sending the unwanted SMS that contain advertisement can make the users feeling disturb and this against the privacy of the mobile users. To overcome these issues, many studies have proposed to detect SMS Spam by using data mining tools. This paper will do a comparative study using five machine learning techniques such as Naïve Bayes, K-NN (K-Nearest Neighbour Algorithm), Decision Tree, Random Forest and Decision Stumps to observe the accuracy result between RapidMiner and WEKA for dataset SMS Spam UCI Machine Learning repository.

Views of STS-4 crew during a training session in the SMS

Science.gov (United States)

1982-01-01

Views of STS-4 crew during a training session in the Shuttle Mission Simulator (SMS) in bldg 5. Astronauts Thomas K. Mattingly, II. (left) and Henry W. Hartsfield, Jr., commander and pilot respectively for STS-4 get in some training time in the SMS.

NMR Spectroscopic Characterization of Methylcobalt(III) Compounds with Classical Ligands. Crystal Structures of [Co(NH(3))(5)(CH(3))]S(2)O(6), trans-[Co(en)(2)(NH(3))(CH(3))]S(2)O(6) (en = 1,2-Ethanediamine), and [Co(NH(3))(6)]-mer,trans-[Co(NO(2))(3)(NH(

DEFF Research Database (Denmark)

Kofod, Pauli; Harris, Pernille; Larsen, Sine

1997-01-01

magnetic resonance spectroscopy and by absorption spectroscopy. Single-crystal X-ray structure determinations at 122.0(5) K were performed on [Co(NH(3))(5)(CH(3))]S(2)O(6) (1), trans-[Co(en)(2)(NH(3))(CH(3))]S(2)O(6) (2), and [Co(NH(3))(6)]-mer,trans-[Co(NO(2))(3)(NH(3))(2)(CH(3))](2)-trans-[Co(NO(2...

Opening the SMS platform to users : Deliverable D7.2 - RISIS project

NARCIS (Netherlands)

van den Besselaar, P.A.A.; Khalili, A.; de Graaf, K.A.; Idrissou, O.A.K.; van Harmelen, Frank

2017-01-01

In this deliverable we describe the SMS (Semantically Mapping Science) data integration platform (http://sms.risis.eu), the technical core within the RISIS data infrastructure for Science, Technology and Innovation Studies (STI). The aim of the platform is to produce richer data to be used in social

The feasibility of using mobile-phone based SMS reminders and conditional cash transfers to improve timely immunization in rural Kenya.

Science.gov (United States)

Wakadha, Hotenzia; Chandir, Subhash; Were, Elijah Victor; Rubin, Alan; Obor, David; Levine, Orin S; Gibson, Dustin G; Odhiambo, Frank; Laserson, Kayla F; Feikin, Daniel R

2013-01-30

Demand-side strategies could contribute to achieving high and timely vaccine coverage in rural Africa, but require platforms to deliver either messages or conditional cash transfers (CCTs). We studied the feasibility of using short message services (SMS) reminders and mobile phone-based conditional cash transfers (CCTs) to reach parents in rural Western Kenya. In a Health and Demographic Surveillance System (HDSS), mothers with children aged 0-3 weeks old were approached to determine who had access to a mobile phone. SMS reminders were sent three days prior to and on the scheduled day of immunization for 1st (age 6 weeks) and 2nd doses (age 10 weeks) of DTP-HepB-Hib (Pentavalent) vaccine, using open-source Rapid SMS software. Approximately $2.00 USD was sent as cash using mPESA, a mobile money transfer platform (2/3 of mothers), or airtime (1/3 of mothers) via phone if the child was vaccinated within 4 weeks of the scheduled date. Follow-up surveys were done when children reached 14 weeks of age. We approached 77 mothers; 72 were enrolled into the study (26% owned a phone and 74% used someone else's). Of the 63 children with known vaccination status at 14 weeks of age, 57 (90%) received pentavalent1 and 54 (86%) received pentavalent2 within 4 weeks of their scheduled date. Of the 61 mothers with follow-up surveys administered at 14 weeks of age, 55 (90%) reported having received SMS reminders. Of the 54 women who reported having received SMS reminders and answered the CCT questions on the survey, 45 (83%) reported receiving their CCT. Most (89%) of mothers in the mPESA group obtained their cash within 3 days of being sent their credit via mobile phone. All mothers stated they preferred CCTs as cash via mobile phone rather than airtime. Of the 9 participants who did not vaccinate their children at the designated clinic 2(22%) cited refusals by husbands to participate in the study. The data show that in rural Western Kenya mobile phone-based strategies are a

Effectiveness of mobile-phone short message service (SMS reminders for ophthalmology outpatient appointments: Observational study

Directory of Open Access Journals (Sweden)

Car Josip

2008-05-01

Full Text Available Abstract Background Non-attendance for hospital outpatient appointments is a significant problem in many countries. It causes suboptimal use of clinical and administrative staff and financial losses, as well as longer waiting times. The use of Short Message Service (SMS appointment reminders potentially offers a cost-effective and time-efficient strategy to decrease non-attendance and so improve the efficiency of outpatient healthcare delivery. Methods An SMS text message was sent to patients with scheduled appointments between April and September 2006 in a hospital ophthalmology department in London, reminding them of their appointments. This group acted as the intervention group. Controls were patients with scheduled ophthalmology appointments who did not receive an SMS or any alternative reminder. Results During the period of the study, 11.2% (50/447 of patients who received an SMS appointment reminder were non-attenders, compared to 18.1% (1720/9512 who did not receive an SMS reminder. Non-attendance rates were 38% lower in patients who received an SMS reminder than in patients who did not receive a reminder (RR of non-attendance = 0.62; 95% CI = 0.48 – 0.80. Conclusion The use of SMS reminders for ophthalmology outpatient appointments was associated with a reduction of 38% in the likelihood of patients not attending their appointments, compared to no appointment reminder. The use of SMS reminders may also be more cost-effective than traditional appointment reminders and require less labour. These findings should be confirmed with a more rigorous study design before a wider roll-out.

Simultaneous multislice magnetic resonance fingerprinting (SMS-MRF) with direct-spiral slice-GRAPPA (ds-SG) reconstruction.

Science.gov (United States)

Ye, Huihui; Cauley, Stephen F; Gagoski, Borjan; Bilgic, Berkin; Ma, Dan; Jiang, Yun; Du, Yiping P; Griswold, Mark A; Wald, Lawrence L; Setsompop, Kawin

2017-05-01

To develop a reconstruction method to improve SMS-MRF, in which slice acceleration is used in conjunction with highly undersampled in-plane acceleration to speed up MRF acquisition. In this work two methods are employed to efficiently perform the simultaneous multislice magnetic resonance fingerprinting (SMS-MRF) data acquisition and the direct-spiral slice-GRAPPA (ds-SG) reconstruction. First, the lengthy training data acquisition is shortened by employing the through-time/through-k-space approach, in which similar k-space locations within and across spiral interleaves are grouped and are associated with a single set of kernel. Second, inversion recovery preparation (IR prepped), variable flip angle (FA), and repetition time (TR) are used for the acquisition of the training data, to increase signal variation and to improve the conditioning of the kernel fitting. The grouping of k-space locations enables a large reduction in the number of kernels required, and the IR-prepped training data with variable FA and TR provide improved ds-SG kernels and reconstruction performance. With direct-spiral slice-GRAPPA, tissue parameter maps comparable to that of conventional MRF were obtained at multiband (MB) = 3 acceleration using t-blipped SMS-MRF acquisition with 32-channel head coil at 3 Tesla (T). The proposed reconstruction scheme allows MB = 3 accelerated SMS-MRF imaging with high-quality T 1 , T 2 , and off-resonance maps, and can be used to significantly shorten MRF acquisition and aid in its adoption in neuro-scientific and clinical settings. Magn Reson Med 77:1966-1974, 2017. © 2016 International Society for Magnetic Resonance in Medicine. © 2016 International Society for Magnetic Resonance in Medicine.

SMS marketing: It's place in mobile commerce and opportunity in the South African market

OpenAIRE

Frik Jansen van Ryssen

2004-01-01

This article investigates Short Message Service (SMS) Marketing's place in the world of mobile commerce (m-commerce). The article also investigates the opportunity that SMS Marketing presents in the South African market. The article indicates a couple of clear guidelines and implications for marketers on how to approach the challenge presented by technological advances that allowed this new trend of mass- and personalised marketing messages via SMS. Advances in the m-commerce field are predic...

Mobile Learning, Teacher Education, and the Sociomaterial Perspective: Analysis of the SMS Story Project

Science.gov (United States)

Koole, Marguerite

2018-01-01

This article is primarily a theoretical piece that uses a model of mobile learning, the FRAME model (Koole 2009), to explore a mobile teacher-training project that took place in Papua New Guinea: the SMS Story. The author takes a sociomaterial perspective, drawing upon Barad's agential realism and Sørensen's multiplicity perspective. As the author…

Rancang Bangun Sistem Pemesanan Tiket Bus Kupang-Atambua Berbasis SMS Gateway

Directory of Open Access Journals (Sweden)

Emerensiana Ngaga

2016-11-01

Full Text Available Bus merupakan alat transportasi yang paling banyak digunakan masyarakat karena harga yang murah dan masih terjangkau untuk masyarakat kalangan ekonomi menengah ke bawah.  Umumnya pemesanan tiket bus dilakukan dengan mendatangi langsung tempat penjualan tiket bus atau dengan cara menelepon ke kantor agen. Proses pemesanan seperti ini  memiliki kekurangan dimana pegawai kerepotan dalam mencatat dan seringkali terjadi kesalahan dalam mencatat pemesanan tiket. Sedangkan untuk waktu pemesanan, umumnya calon penumpang melakukan pemesanan tiket, satu atau dua hari sebelum keberangkatan dan ada juga yang tidak sempat memesan tiket beberapa hari sebelumnya dan melakukan pembelian tiket pada hari keberangkatan sehingga sering kali tidak mendapatkan tiket. Penelitian ini bertujuan merancang bangun sistem pemesanan tiket bus berbasis SMS Gateway yang memberikan kemudahan layanan pemesanan tiket bus bagi masyarakat secara jarak jauh serta kemudahan mengetahui informasi penjadwalan bus dengan cepat. Aplikasi dibangun menggunakan metode Unified Process, dengan bahasa pemrograman Java NetBeansIDE 7.3.1, MySQL sebagai database dan Gammu sebagai software untuk membantu pembangunan aplikasi SMS Gateway. Hasil dari penelitian ini adalah sebuah sistem pemesanan tiket bus yang memberikan alternatif baru proses pemesanan tiket bus secara baik tanpa ada permasalahan jarak dan waktu. Selain itu masyarakat juga dapat mengetahui informasi jadwal bus, harga tiket dan juga informasi bila terjadi perubahan jadwal keberangkatan bus.   Kata kunci— Bus, Tiket, SMS Gateway, Unified Process

Perancangan dan Implementasi Sistem Informasi Layanan Short Messaging Service (SMS)

OpenAIRE

Rossy W, Cahyo; Wellem, Theophilus; Utomo, Wiranto Herry

2006-01-01

Development progress of Communication technology increase in a line with the people demand of the technology, such as Wireless communication technology, especially, Global System for Mobile Communication (GSM), which known as a digital mobile phone. Mobile phone used to send and receive short message in GSM network known as Short Messaging Service (SMS), besides communicate with another person by voice. In recent years, SMS is not just used for text-based communication tool between mobile pho...

Texting Styles and Information Change of SMS Text Messages in Filipino

Science.gov (United States)

Cabatbat, Josephine Jill T.; Tapang, Giovanni A.

2013-02-01

We identify the different styles of texting in Filipino short message service (SMS) texts and analyze the change in unigram and bigram frequencies due to these styles. Style preference vectors for sample texts were calculated and used to identify the style combination used by an average individual. The change in Shannon entropy of the SMS text is explained in light of a coding process.

SMS-reminder for vaccination in Africa: research from published, unpublished and grey literature.

Science.gov (United States)

Manakongtreecheep, Kasidet

2017-01-01

Immunization for children against vaccine-preventable diseases is one of the most important health intervention method in the world, both in terms of its health impact and cost-effectiveness. Through EPI and various other programs such as the Decades of Vaccines, immunization has been improving the health of children around the world. However, this progress falls short of global immunization targets of the Global Vaccine Action Plan (GVAP). Furthermore, the African region still lags behind in immunization, and suffers from a high proportion of vaccine preventable diseases as a result. Reminders and recall for vaccination have been shown to improve health care-seeking behaviours, and have been recommended for application in routine and supplemental measles immunization activities. With mobile phones becoming more accessible in Africa, SMS vaccine reminder system has been proposed as a convenient and easily scalable way to inform caregivers of the disease and the importance of immunization, to address any concerns related to immunization safety, and to remind them of vaccination schedules and campaigns. There have been 6 published articles and 1 unpublished article on the effect of SMS reminder system for immunization in Africa. The studies done has shown that SMS vaccination reminder has led to improvements in vaccination uptakes in various metrics, whether is through the increase in vaccination coverage, decrease in dropout rates, increase in completion rate, or decrease in delay for vaccination.

ICAO safety management systems (SMS) development in environmental contexts: A field study of greater China

Science.gov (United States)

Leib, Steven M.

This was a mixed-methods exploratory study to investigate association between environmental context and the implementation status of Safety Management Systems (SMS) at airports in Greater China. Using a framework of Institutional Theory, this study looked at three regions of Greater China and explored internal and external environments of SMS at airports within each region. It used ICAO standards to evaluate the implementation status of SMS at those airports based on the perceptions of 126 participants. This research also employed snowballing technique to spread a survey tool to participants in Greater China through several key gatekeepers, and then applied the Delphi method for interviews with key gatekeepers themselves. Analysis of the data suggested several associations between various sub-concepts of the external environment and different components of SMS in the three regions. In addition, the data suggested a relationship between the internal environment as a whole and the overall status of SMS implementation in each region. Lastly, the study makes several recommendations for future research regarding global standards implemented in local environments, the evaluation of SMS implementation status, and the theoretical implications of this study.

78 FR 66420 - Proposed Enhancements to the Motor Carrier Safety Measurement System (SMS) Public Web Site

Science.gov (United States)

2013-11-05

... individual submitting the comment (or signing the comment, if submitted on behalf of an association, business....fmcsa.dot.gov/SMS . From the start of CSA, FMCSA expected to modify SMS as new data and additional... easier, more intuitive navigation and user-friendly features and descriptions to clarify the SMS's role...

Development of a scale to measure problem use of short message service: the SMS Problem Use Diagnostic Questionnaire.

Science.gov (United States)

Rutland, J Brian; Sheets, Tilman; Young, Tony

2007-12-01

This exploratory study examines a subset of mobile phone use, the compulsive use of short message service (SMS) text messaging. A measure of SMS use, the SMS Problem Use Diagnostic Questionnaire (SMS-PUDQ), was developed and found to possess acceptable reliability and validity when compared to other measures such as self-reports of time spent using SMS and scores on a survey of problem mobile phone use. Implications for the field of addiction research, technological and behavioral addictions in particular, are discussed, and directions for future research are suggested.

STS-37 Mission Specialist (MS) Ross during simulation in JSC's FB-SMS

Science.gov (United States)

1991-01-01

STS-37 Mission Specialist (MS) Jerry L. Ross 'borrows' the pilots station to rehearse some of his scheduled duties for his upcoming mission. He is on the flight deck of the fixed-based (FB) shuttle mission simulator (SMS) during this unsuited simulation. The SMS is part of JSC's Mission Simulation and Training Facility Bldg 5.

Pengembangan SMS Gateway Layanan Informasi Akademik di STMIK GI MDP

Directory of Open Access Journals (Sweden)

Fransiska Prihatini Sihotang

2017-08-01

Full Text Available Information technology can be utilized in education such as e-Learning and Academic Information System. STMIK GI MDP has applied information technology that provides ease for the dissemination of academic information to students. However, the parents of the students have not obtained the academic information of their children due to the lack of internet-related knowledge. Therefore, this study aims to create a service that is able to convey information to parents directly with SMS Gateway service. This research begins with the collection of user needs through observation techniques and interviews to academic staff and parents. Then performed the required feature analysis. Then the design of SMS Gateway application that will be embedded in existing academic applications and coding system. Gammu is used as a link between applications with mobile phones. The result of this research is the application of SMS Gateway service that can give the student academic information to the parents.

Interim report on modeling sorption with EQ3/6

International Nuclear Information System (INIS)

Viani, B.

1988-01-01

Reversible, equilibrium models of sorption to be incorporated into the EQ3/6 geochemical modeling package are summarized. Empirical sorption models as formulated in linear, Langmuir, and Freundlich isotherms will be developed as options to EQ3/6. This work will be done at LLNL. Options for modeling sorption using surface- complexation constructs (diffuse, constant capacitance, and triple-layer models) will also be developed. Development of the surface-complexation options will require part of the work be done under contract. 27 refs., 1 fig

Recall effect of short message service (SMS) as a complementary marketing communications instrument

NARCIS (Netherlands)

Wouters, J.P.M.; Wetzels, M.G.M.

2006-01-01

A quasi-experimental study was designed to investigate the recall effect of Short Message Service (SMS) as a complementary marketing communications instrument. An experimental group (EG) was formed, consisting of people who had called an SMS number mentioned in a car brand campaign. A control group

Short message service (SMS)-based intervention targeting alcohol consumption among university students: study protocol of a randomized controlled trial.

Science.gov (United States)

Thomas, Kristin; Bendtsen, Marcus; Linderoth, Catharina; Karlsson, Nadine; Bendtsen, Preben; Müssener, Ulrika

2017-04-04

Despite significant health risks, heavy drinking of alcohol among university students is a widespread problem; excessive drinking is part of the social norm. A growing number of studies indicate that short message service (SMS)-based interventions are cost-effective, accessible, require limited effort by users, and can enable continuous, real-time, brief support in real-world settings. Although there is emerging evidence for the effect of SMS-based interventions in reducing alcohol consumption, more research is needed. This study aims to test the effectiveness of a newly developed SMS-based intervention targeting excessive alcohol consumption among university and college students in Sweden. The study is a two-arm randomized controlled trial with an intervention (SMS programme) and a control (treatment as usual) group. Outcome measures will be investigated at baseline and at 3-month follow up. The primary outcome is total weekly alcohol consumption. Secondary outcomes are frequency of heavy episodic drinking, highest estimated blood alcohol concentration and number of negative consequences due to excessive drinking. This study contributes knowledge on the effect of automatized SMS support to reduce excessive drinking among students compared with existing support such as Student Health Centres. ISRCTN.com, ISRCTN95054707 . Registered on 31 August 2016.

SMS/MMS-based Enhancements to the Community Health ...

International Development Research Centre (IDRC) Digital Library (Canada)

The Community Health Information Tracking System (CHITS) is an electronic public ... SMS can improve the timeliness and ease of reporting notifiable diseases, and ... development and production to benefit farmers across the Global South.

SMS for Life: a pilot project to improve anti-malarial drug supply management in rural Tanzania using standard technology

Science.gov (United States)

2010-01-01

Background Maintaining adequate supplies of anti-malarial medicines at the health facility level in rural sub-Saharan Africa is a major barrier to effective management of the disease. Lack of visibility of anti-malarial stock levels at the health facility level is an important contributor to this problem. Methods A 21-week pilot study, 'SMS for Life', was undertaken during 2009-2010 in three districts of rural Tanzania, involving 129 health facilities. Undertaken through a collaborative partnership of public and private institutions, SMS for Life used mobile telephones, SMS messages and electronic mapping technology to facilitate provision of comprehensive and accurate stock counts from all health facilities to each district management team on a weekly basis. The system covered stocks of the four different dosage packs of artemether-lumefantrine (AL) and quinine injectable. Results Stock count data was provided in 95% of cases, on average. A high response rate (≥ 93%) was maintained throughout the pilot. The error rate for composition of SMS responses averaged 7.5% throughout the study; almost all errors were corrected and messages re-sent. Data accuracy, based on surveillance visits to health facilities, was 94%. District stock reports were accessed on average once a day. The proportion of health facilities with no stock of one or more anti-malarial medicine (i.e. any of the four dosages of AL or quinine injectable) fell from 78% at week 1 to 26% at week 21. In Lindi Rural district, stock-outs were eliminated by week 8 with virtually no stock-outs thereafter. During the study, AL stocks increased by 64% and quinine stock increased 36% across the three districts. Conclusions The SMS for Life pilot provided visibility of anti-malarial stock levels to support more efficient stock management using simple and widely available SMS technology, via a public-private partnership model that worked highly effectively. The SMS for Life system has the potential to alleviate

SMS for Life: a pilot project to improve anti-malarial drug supply management in rural Tanzania using standard technology

Directory of Open Access Journals (Sweden)

Mwafongo Winfred

2010-10-01

Full Text Available Abstract Background Maintaining adequate supplies of anti-malarial medicines at the health facility level in rural sub-Saharan Africa is a major barrier to effective management of the disease. Lack of visibility of anti-malarial stock levels at the health facility level is an important contributor to this problem. Methods A 21-week pilot study, 'SMS for Life', was undertaken during 2009-2010 in three districts of rural Tanzania, involving 129 health facilities. Undertaken through a collaborative partnership of public and private institutions, SMS for Life used mobile telephones, SMS messages and electronic mapping technology to facilitate provision of comprehensive and accurate stock counts from all health facilities to each district management team on a weekly basis. The system covered stocks of the four different dosage packs of artemether-lumefantrine (AL and quinine injectable. Results Stock count data was provided in 95% of cases, on average. A high response rate (≥ 93% was maintained throughout the pilot. The error rate for composition of SMS responses averaged 7.5% throughout the study; almost all errors were corrected and messages re-sent. Data accuracy, based on surveillance visits to health facilities, was 94%. District stock reports were accessed on average once a day. The proportion of health facilities with no stock of one or more anti-malarial medicine (i.e. any of the four dosages of AL or quinine injectable fell from 78% at week 1 to 26% at week 21. In Lindi Rural district, stock-outs were eliminated by week 8 with virtually no stock-outs thereafter. During the study, AL stocks increased by 64% and quinine stock increased 36% across the three districts. Conclusions The SMS for Life pilot provided visibility of anti-malarial stock levels to support more efficient stock management using simple and widely available SMS technology, via a public-private partnership model that worked highly effectively. The SMS for Life system has

Efficacy of a text messaging (SMS) based intervention for adults with hypertension: protocol for the StAR (SMS Text-message Adherence suppoRt trial) randomised controlled trial.

Science.gov (United States)

Bobrow, Kirsty; Brennan, Thomas; Springer, David; Levitt, Naomi S; Rayner, Brian; Namane, Mosedi; Yu, Ly-Mee; Tarassenko, Lionel; Farmer, Andrew

2014-01-11

Interventions to support people with hypertension in attending clinics and taking their medication have potential to improve outcomes, but delivery on a wide scale and at low cost is challenging. Some trials evaluating clinical interventions using short message service (SMS) text-messaging systems have shown important outcomes, although evidence is limited. We have developed a novel SMS system integrated with clinical care for use by people with hypertension in a low-resource setting. We aim to test the efficacy of the system in improving blood pressure control and treatment adherence compared to usual care. The SMS Text-message Adherence suppoRt trial (StAR) is a pragmatic individually randomised three-arm parallel group trial in adults treated for hypertension at a single primary care centre in Cape Town, South Africa. The intervention is a structured programme of clinic appointment, medication pick-up reminders, medication adherence support and hypertension-related education delivered remotely using an automated system with either informational or interactive SMS text-messages. Usual care is supplemented by infrequent non-hypertension related SMS text-messages. Participants are 1:1:1 individually randomised, to usual care or to one of the two active interventions using minimisation to dynamically adjust for gender, age, baseline systolic blood pressure, years with hypertension, and previous clinic attendance. The primary outcome is the change in mean systolic blood pressure at 12-month follow-up from baseline measured with research staff blinded to trial allocation. Secondary outcomes include the proportion of patients with 80% or more of days medication available, proportion of participants achieving a systolic blood pressure less than 140 mmHg and a diastolic blood pressure less than 90 mmHg, hospital admissions, health status, retention in clinical care, satisfaction with treatment and care, and patient related quality of life. Anonymised demographic data

(1S,3S,8R,9S,10R-9,10-Epoxy-3,7,7,10-tetramethyltricyclo[6.4.0.01,3]dodecane

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Abdoullah Bimoussa

2014-04-01

Full Text Available The title compound, C16H26O, was synthesized by treating (1S,3S,8R-3,7,7,10-tetramethyltricyclo[6.4.0.01,3]dodec-9-ene with metachloroperbenzoic acid. The molecule is built up from two fused six- and seven-membered rings. The six-membered ring has a half-chair conformation, whereas the seven-membered ring displays a boat conformation. In the crystal, there are no significant intermolecular interactions present.

Pengembangan Sistem Informasi Paduan Suara Mahasiswa Universitas Diponegoro Berbasis Web dan SMS

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Liga Filosa

2014-11-01

Full Text Available Today, technology has become ours primary need. The ease of getting or giving information by using technology make people do their jobs easily. Diponegoro University Choir (PSM is one of choir that have good reputation in local, national and international. But PSM do not have any official website that can gives information to the people. Every years, the number of recruits is increasing, and the process of registeration is still done manually. Based on that problem, the organization needs an web-based Information System and SMS gateway to support information giving process and its own member data maintenance.The Information System is built using PHP Framework Codeignitier language program, javascript for the dynamic appearance, and MySQL for the database. The System’s development process uses waterfall method. This method is included with analysis of needs, analysis, design, implementation and testing. The model of system is built using object oriented UML (Unified Modeling Language includes Use Case diagram, Class diagram and Sequence diagram

STS-49 crew in JSC's FB Shuttle Mission Simulator (SMS) during simulation

Science.gov (United States)

1992-01-01

STS-49 Endeavour, Orbiter Vehicle (OV) 105, crewmembers participate in a simulation in JSC's Fixed Base (FB) Shuttle Mission Simulator (SMS) located in the Mission Simulation and Training Facility Bldg 5. Wearing launch and entry suits (LESs) and launch and entry helmets (LEH) and seated on the FB-SMS middeck are (left to right) Mission Specialist (MS) Thomas D. Akers, MS Kathryn C. Thornton, and MS Pierre J. Thuot.

SMS-Based Medical Diagnostic Telemetry Data Transmission Protocol for Medical Sensors

Science.gov (United States)

Townsend, Ben; Abawajy, Jemal; Kim, Tai-Hoon

2011-01-01

People with special medical monitoring needs can, these days, be sent home and remotely monitored through the use of data logging medical sensors and a transmission base-station. While this can improve quality of life by allowing the patient to spend most of their time at home, most current technologies rely on hardwired landline technology or expensive mobile data transmissions to transmit data to a medical facility. The aim of this paper is to investigate and develop an approach to increase the freedom of a monitored patient and decrease costs by utilising mobile technologies and SMS messaging to transmit data from patient to medico. To this end, we evaluated the capabilities of SMS and propose a generic communications protocol which can work within the constraints of the SMS format, but provide the necessary redundancy and robustness to be used for the transmission of non-critical medical telemetry from data logging medical sensors. PMID:22163845

SMS-Based Medical Diagnostic Telemetry Data Transmission Protocol for Medical Sensors

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Tai-Hoon Kim

2011-04-01

Full Text Available People with special medical monitoring needs can, these days, be sent home and remotely monitored through the use of data logging medical sensors and a transmission base-station. While this can improve quality of life by allowing the patient to spend most of their time at home, most current technologies rely on hardwired landline technology or expensive mobile data transmissions to transmit data to a medical facility. The aim of this paper is to investigate and develop an approach to increase the freedom of a monitored patient and decrease costs by utilising mobile technologies and SMS messaging to transmit data from patient to medico. To this end, we evaluated the capabilities of SMS and propose a generic communications protocol which can work within the constraints of the SMS format, but provide the necessary redundancy and robustness to be used for the transmission of non-critical medical telemetry from data logging medical sensors.

Conducting Surveys and Data Collection: From Traditional to Mobile and SMS-based Surveys

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Iftikhar Alam

2014-08-01

Full Text Available Fresh, bias-free and valid data collected using different survey modes is considered an essential requirement for smooth functioning and evolution of an organization. Surveys play a major role in making in-time correct decisions and generating reports. The aim of this study is to compare and investigate state-of-the-art in different survey modes including print, email, online, mobile and SMS-based surveys. Results indicated that existing methods are neither complete nor sufficient to fulfil the overall requirements of an organization which primarily rely on surveys. Also, it shows that SMS is a dominant method for data collection due to its pervasiveness. However, existing SMS-based data collection has limitations like limited number of characters per SMS, single question per SMS and lake of multimedia support. Recent trends in data collection emphasis on data collection applications for smart phones. However, in developing countries low-end mobile devices are still extensively used which makes the data collection difficult from man in the street. The paper conclude that existing survey modes and methods should be improved to get maximum responses quickly in low cost manner. The study has contributed to the area of surveying and data collection by analysing different factors such as cost, time and response rate. The results of this study can help practitioners in creating a more successful surveying method for data collection that can be effectively used for low budget projects in developed as well as developing countries.

PASTE: patient-centered SMS text tagging in a medication management system.

Science.gov (United States)

Stenner, Shane P; Johnson, Kevin B; Denny, Joshua C

2012-01-01

To evaluate the performance of a system that extracts medication information and administration-related actions from patient short message service (SMS) messages. Mobile technologies provide a platform for electronic patient-centered medication management. MyMediHealth (MMH) is a medication management system that includes a medication scheduler, a medication administration record, and a reminder engine that sends text messages to cell phones. The object of this work was to extend MMH to allow two-way interaction using mobile phone-based SMS technology. Unprompted text-message communication with patients using natural language could engage patients in their healthcare, but presents unique natural language processing challenges. The authors developed a new functional component of MMH, the Patient-centered Automated SMS Tagging Engine (PASTE). The PASTE web service uses natural language processing methods, custom lexicons, and existing knowledge sources to extract and tag medication information from patient text messages. A pilot evaluation of PASTE was completed using 130 medication messages anonymously submitted by 16 volunteers via a website. System output was compared with manually tagged messages. Verified medication names, medication terms, and action terms reached high F-measures of 91.3%, 94.7%, and 90.4%, respectively. The overall medication name F-measure was 79.8%, and the medication action term F-measure was 90%. Other studies have demonstrated systems that successfully extract medication information from clinical documents using semantic tagging, regular expression-based approaches, or a combination of both approaches. This evaluation demonstrates the feasibility of extracting medication information from patient-generated medication messages.

How Can Mobile SMS Communication Support and Enhance a First Year Undergraduate Learning Environment?

Science.gov (United States)

Jones, Geraldine; Edwards, Gabriele; Reid, Alan

2009-01-01

In this paper we discuss a case study investigating how the academic and personal development of first year students on an undergraduate sports education degree can be supported and enhanced with mobile SMS (Short Message Service) communication. SMS-based technologies were introduced in response to students' particular needs (in transition to…

STS-29 Commander Coats in JSC fixed base (FB) shuttle mission simulator (SMS)

Science.gov (United States)

1986-01-01

STS-29 Discovery, Orbiter Vehicle (OV) 103, Commander Michael L. Coats sits at commanders station forward flight deck controls in JSC fixed base (FB) shuttle mission simulator (SMS). Coats, wearing communications kit assembly headset and flight coveralls, looks away from forward control panels to aft flight deck. Pilots station seat back appears in foreground. FB-SMS is located in JSC Mission Simulation and Training Facility Bldg 5.

Extension of the EQ3/6 computer codes to geochemical modeling of brines

Energy Technology Data Exchange (ETDEWEB)

Jackson, K.J.; Wolery, T.J.

1984-10-23

Recent modifications to the EQ3/6 geochemical modeling software package provide for the use of Pitzer's equations to calculate the activity coefficients of aqueous species and the activity of water. These changes extend the range of solute concentrations over which the codes can be used to dependably calculate equilibria in geochemical systems, and permit the inclusion of ion pairs, complexes, and undissociated acids and bases as explicit component species in the Pitzer model. Comparisons of calculations made by the EQ3NR and EQ6 compuer codes with experimental data confirm that the modifications not only allow the codes to accurately evaluate activity coefficients in concentrated solutions, but also permit prediction of solubility limits of evaporite minerals in brines at 25/sup 0/C and elevated temperatures. Calculations for a few salts can be made at temperatures up to approx. 300/sup 0/C, but the temperature range for most electrolytes is constrained by the availability of requisite data to values less than or equal to 100/sup 0/C. The implementation of Pitzer's equations in EQ3/6 allows application of these codes to problems involving calculation of geochemical equilibria in brines; such as evaluation of the chemical environment which might be anticipated for nuclear waste canisters located in a salt repository. 26 references, 3 figures, 1 table.

Perancangan Sistem Kendali pada Alat Listrik Rumah Tangga Menggunakan Media Pesan Singkat (SMS

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Hefmi Fauzan Imron

2016-08-01

Full Text Available Listrik merupakan salah satu kebutuhan penting dalam kehidupan dan selama ini ketergantungan manusia terhadap listrik menimbulkan kebiasaan buruk. Banyak orang terkadang membiarkan suatu alat listrik ditinggal dalam kondisi menyala yang dapat menyebabkan pemborosan dan pemborosan sendiri bukanlah satu satunya masalah yang akan timbul namun juga dapat menyebabkan kebakaran. Oleh sebab itu, perlu dilakukan penelitian dengan mengembangkan sistem yang dapat mengontrol dan mengetahui status alat listrik yang bisa diakses dari jarak jauh, contohnya melalui pesan singkat (SMS. Sistem terdiri atas perangkat keras dan perangkat lunak. Perangkat keras terdiri atas sensor arus sebagai masukan arus listrik, Arduino Mega sebagai mikrokontroler, sensor PIR sebagai inputan mendeteksi keberadaan panas tubuh manusia, relay sebagai keluaran yang berfungsi sebagai saklar dan SIM900 Mini Modul sebagai penerima dan pengirim pesan singkat (SMS. Perangkat lunak dibuat menggunakan bahasa C dengan Arduino IDE. Kegiatan penelitian meliputi studi literatur, analisis spesifikasi kebutuhan, perancangan sistem, implementasi, dan pengujian. Hasil pengujian menunjukkan sistem mampu menyalakan dan mematikan terminal yang terhubung dengan alat listrik menggunakan perintah pesan singkat (SMS, sistem mampu mendeteksi keberadaan panas tubuh manusia, sistem mampu memeriksa keadaan terminal dalam posisi menyala ataupun tidak, sistem mampu memberi notifikasi melalui pesan singkat (SMS tentang penggunaan komponen listrik yang dilalaikan dan bila ada orang asing yang ingin masuk kedalam sistem. Electricity is one of the important needs in life and for human dependency on electricity cause bad habits. Many people sometimes let an electrical appliance was left in light conditions that can cause waste and waste itself is not the only issue that will arise, but also can cause a fire. Therefore, research must be done to develop a system that can control and know the status of power tools

(3R,6S,7aS-3-Phenyl-6-(phenylsulfanylperhydropyrrolo[1,2-c]oxazol-5-one

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Anthony D. Woolhouse

2009-05-01

Full Text Available Molecules of the title compound [systematic name: (2R,5S,7S-2-phenyl-7-phenylsulfanyl-1-aza-3-oxabicyclo[3.3.0]octan-8-one], C18H17NO2S, form high quality crystals even though they are only packed using C—H...O(carbonyl and weak C—H...S interactions. The dihedral angle between the aromatic rings is 85.53 (5°. The fused rings adopt envelope and twist conformations.

A conceptual investigation of variables affecting the success and acceptance of SMS Marketing in Iran.

Science.gov (United States)

Adhami, A; Rabiee, A; Adhami, M

2015-01-01

This paper's aim was to develop a conceptual overview of SMS marketing and delineate factors of new communications technologies on business practice. This study, which was a descriptive survey, was built on primary and secondary data source including a literature review of SMS marketing and a Questionnaire were used as the primary means of collecting secondary data. The sample size of 300 patients was determined according to the Cochran formula. Moreover, data analysis was done in SPSS by using linear regression, chi-square, t-test and Binomial test. According to the research, sex, age, education, relevance, timeliness, reliability to sender, sense of control were variables affecting the SMS marketing acceptance. This paper was qualitative and provided a solid conceptual foundation for the future empirical research on e- marketing. The potential limitation was related to the broad user of computer and mobile. In this research, we considered SMS marketing, Mobile marketing, SMS advertising as the same subject. This research will be a useful resource with important insight into the factors that may encourage or determine consumer acceptance of this new form of direct marketing. This paper addressed an important timely issue, and added to the body of literature and knowledge focusing on e-marketing.

Sistem kontrol inventori pemasokan barang Secara Real Time Menggunakan Vendor-Managed Inventory (VMI dan Short Message Service (SMS

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Rinaldo Turang

2016-01-01

Full Text Available This research underlines the urgency of real-time stock replenishment control system for distributors using vendor-managed inventory. It is valuable in improving corporate performance in lowering inventory cost as well as making better customer service due to the cut made in ordering cycle. The system produces real-time information on stock available at the retailing stores. Stock replenishment can then be done by the distributor at the right time. Using Short Message Service (SMS as a one-way information channel from retailers to their distributor, the data of every transaction of the supervised item are processed by a rule-based forward-chaining inference system to determine the item’s availability in stores. Folowing steps in Rapid Application Development (RAD, the construction of this system takes place through business modeling, data modeling, process modeling of VMI system, then the application is generated and tested as a prototype. The results are: the stock replenishment control system are able to make transactional data at the stores transparent to the distributor, facilitating the continuation in stock delivery. System architecture reduces the time needed to access information about sales on supervised item by using SMS shortcut. This control system developed in stores can be operationally independent from the retailing systems. Rule-based forward-chaining inference technique processes facts on stock variations, resulting in stock replenishment notification such as normal, reserve, and depleted warning. Keywords: VMI, inventory; Stock replenishment; Rule-based reasoning; Forward-chaining system, RAD

Sms-Based Home Management System

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Paing Soe Oo

2015-08-01

Full Text Available Mobile phones are widely used nowadays for different application such as wireless control and monitoring due to its availability and ease of use. The implemented system is based on global system mobile GSM network by using short message service SMS. The design mainly contains a GSM modem and Arduino Uno. In this work the system will be described how to manage and control home appliances using mobile phone people can use this system to do things in their home from a far place before they reach home. For instance user may controlmanage hisher home lighting door or water pump which needed in daily life in different area House Office or factory etc. when they are away from home. The user can check the condition in the home that light is on or off door is locked or unlocked water pump is on or off and so on. If the time taken for this appliances to perform a task is known that can also be set so that if the time elapsed the appliance will automatically switch off itself. The control is done by sending a specific SMS messages from smart phone to a SIM900 and Arduino Uno which is connected to the appliance once the message is received the SIM 900 will send the command to a microcontroller in Arduino for controlling the appliance appropriately. Also feedback status of three devices can be requested in designed system.

Case study of atmospheric correction on CCD data of HJ-1 satellite based on 6S model

International Nuclear Information System (INIS)

Xue, Xiaoiuan; Meng, Oingyan; Xie, Yong; Sun, Zhangli; Wang, Chang; Zhao, Hang

2014-01-01

In this study, atmospheric radiative transfer model 6S was used to simulate the radioactive transfer process in the surface-atmosphere-sensor. An algorithm based on the look-up table (LUT) founded by 6S model was used to correct (HJ-1) CCD image pixel by pixel. Then, the effect of atmospheric correction on CCD data of HJ-1 satellite was analyzed in terms of the spectral curves and evaluated against the measured reflectance acquired during HJ-1B satellite overpass, finally, the normalized difference vegetation index (NDVI) before and after atmospheric correction were compared. The results showed: (1) Atmospheric correction on CCD data of HJ-1 satellite can reduce the ''increase'' effect of the atmosphere. (2) Apparent reflectance are higher than those of surface reflectance corrected by 6S model in band1∼band3, but they are lower in the near-infrared band; the surface reflectance values corrected agree with the measured reflectance values well. (3)The NDVI increases significantly after atmospheric correction, which indicates the atmospheric correction can highlight the vegetation information

EQ3/6: status and applications

Energy Technology Data Exchange (ETDEWEB)

Wolery, T.J.; Isherwood, D.J.; Jackson, K.J.; Delany, J.M.; Puigdomenech, I.

1984-12-01

EQ3/6 is a set of related computer codes and data files for use in geochemical modeling of aqueous systems. The EQ3/6 package centers around two large computer codes, EQ3NR and EQ6, which are supported by a common thermodynamic data base. EQ3NR is a speciation-solubility code, whose function is to compute a model of the state of an aqueous solution. This code is very flexible in terms of the input that it will accept. EQ6 is a reaction-path code, which calculates models of changes in aqueous systems as they proceed toward a state of overall chemical equilibrium. EQ3/6 prior to FY83 had no capability for modeling brines, because the approximations for calculating the thermodynamic activity of water and the activity coefficients of the solute species were restricted to low ionic strengths ({le} 1.0 molal). An option has been added to use Pitzer`s equations for such calculations. At present, EQ3/6 contains two alternate Pitzer coefficient data bases. Several improvements have been made to the EQ6 code. Prior to FY83, the code could run models of mineral dissolution kinetics, but could not calculate models of precipitation kinetics. This problem has been overcome by additional code development. The speed of non-kinetic EQ6 calculations has recently been enhanced by the creation of two new calculational modes, economy mode and super economy mode. A calculational mode to simulate systems open to large gas reservoirs has also been developed. 34 references.

Mutagenic and cytotoxic properties of 6-thioguanine, S6-methylthioguanine, and guanine-S6-sulfonic acid.

Science.gov (United States)

Yuan, Bifeng; Wang, Yinsheng

2008-08-29

Thiopurine drugs, including 6-thioguanine ((S)G), 6-mercaptopurine, and azathioprine, are widely employed anticancer agents and immunosuppressants. The formation of (S)G nucleotides from the thiopurine prodrugs and their subsequent incorporation into nucleic acids are important for the drugs to exert their cytotoxic effects. (S)G in DNA can be methylated by S-adenosyl-l-methionine to give S(6)-methylthioguanine (S(6)mG) and oxidized by UVA light to render guanine-S(6)-sulfonic acid ((SO3H)G). Here, we constructed single-stranded M13 shuttle vectors carrying a (S)G, S(6)mG, or (SO3H)G at a unique site and allowed the vectors to propagate in wild-type and bypass polymerase-deficient Escherichia coli cells. Analysis of the replication products by using the competitive replication and adduct bypass and a slightly modified restriction enzyme digestion and post-labeling assays revealed that, although none of the three thionucleosides considerably blocked DNA replication in all transfected E. coli cells, both S(6)mG and (SO3H)G were highly mutagenic, which resulted in G-->A mutation at frequencies of 94 and 77%, respectively, in wild-type E. coli cells. Deficiency in bypass polymerases does not result in alteration of mutation frequencies of these two lesions. In contrast to what was found from previous steady-state kinetic analysis, our data demonstrated that 6-thioguanine is mutagenic, with G-->A transition occurring at a frequency of approximately 10%. The mutagenic properties of 6-thioguanine and its derivatives revealed in the present study offered important knowledge about the biological implications of these thionucleosides.

Interleukin-6 induces S100A9 expression in colonic epithelial cells through STAT3 activation in experimental ulcerative colitis.

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Min Jeoung Lee

Full Text Available BACKGROUND: Intestinal epithelium is essential for maintaining normal intestinal homeostasis; its breakdown leads to chronic inflammatory pathologies, such as inflammatory bowel diseases (IBDs. Although high concentrations of S100A9 protein and interleukin-6 (IL-6 are found in patients with IBD, the expression mechanism of S100A9 in colonic epithelial cells (CECs remains elusive. We investigated the role of IL-6 in S100A9 expression in CECs using a colitis model. METHODS: IL-6 and S100A9 expression, signal transducer and activator of transcription 3 (STAT3 phosphorylation, and infiltration of immune cells were analyzed in mice with dextran sulfate sodium (DSS-induced colitis. The effects of soluble gp130-Fc protein (sgp130Fc and S100A9 small interfering (si RNA (si-S100A9 on DSS-induced colitis were evaluated. The molecular mechanism of S100A9 expression was investigated in an IL-6-treated Caco-2 cell line using chromatin immunoprecipitation assays. RESULTS: IL-6 concentrations increased significantly in the colon tissues of DSS-treated mice. sgp130Fc or si-S100A9 administration to DSS-treated mice reduced granulocyte infiltration in CECs and induced the down-regulation of S100A9 and colitis disease activity. Treatment with STAT3 inhibitors upon IL-6 stimulation in the Caco-2 cell line demonstrated that IL-6 mediated S100A9 expression through STAT3 activation. Moreover, we found that phospho-STAT3 binds directly to the S100A9 promoter. S100A9 may recruit immune cells into inflamed colon tissues. CONCLUSIONS: Elevated S100A9 expression in CECs mediated by an IL-6/STAT3 signaling cascade may play an important role in the development of colitis.

Electron collisions with Fe-peak elements: Forbidden transitions between the low lying valence states 3d6, 3d54s, and 3d54p of Fe III

International Nuclear Information System (INIS)

McLaughlin, B.M.; Scott, M.P.; Sunderland, A.G.; Noble, C.J.; Burke, V.M.; Ramsbottom, C.A.; Reid, R.H.G.; Hibbert, A.; Bell, K.L.; Burke, P.G.

2007-01-01

Effective collision strengths are presented for the Fe-peak element Fe III at electron temperatures (T e in degrees Kelvin) in the range 2 x 10 3 to 1 x 10 6 . Forbidden transitions results are given between the 3d 6 , 3d 5 4s, and the 3d 5 4p manifolds applicable to the modeling of laboratory and astrophysical plasmas

Health promotion via SMS improves hypertension knowledge for deaf South Africans.

Science.gov (United States)

Haricharan, Hanne Jensen; Heap, Marion; Hacking, Damian; Lau, Yan Kwan

2017-08-18

Signing Deaf South Africans have limited access to health information. As a result, their knowledge about health is limited. Cell phone usage in South Africa is high. This study aimed to assess whether a short message service (SMS)-based health promotion campaign could improve Deaf people's knowledge of hypertension and healthy living. Additionally, the study aimed to assess the acceptability of using SMSs for health promotion targeting Deaf people. A baseline questionnaire assessed participants' knowledge about hypertension before an SMS-based information campaign was conducted. After the campaign, an exit questionnaire was conducted, containing the same questions as the baseline questionnaire with additional questions about general acceptability and communication preferences. Results were compared between baseline and exit, using McNemar's test, paired t-test and Wilcoxon signed-rank test. Focus groups aimed to get further information on the impact and acceptability of SMSs. The focus groups were analysed using inductive thematic analysis. The campaign recruited 82 participants for the baseline survey, but due to significant loss-to-follow-up and exclusions only 41 participants were included in the analysis of the survey. The majority (60%) were men. Eighty percent were employed, while 98% had not finished high school. The campaign showed a statistically significant improvement in overall knowledge about hypertension and healthy living amongst participants. Six individual questions out of 19 also showed a statistically significant improvement. Despite this, participants in focus groups found the medical terminology difficult to understand. Several ways of improving SMS campaigns for the Deaf were identified. These included using using pictures, using 'signed' SMSs, combining SMSs with signed drama and linking SMS-campaigns to an interactive communication service that would enable the Deaf to pose questions for clarification. Focus groups suggested that

SMS/MMS-based Enhancements to the Community Health ...

International Development Research Centre (IDRC) Digital Library (Canada)

12 août 2008 ... This project will explore the potential of short message service (SMS) and multimedia messaging service (MMS) to meet the information needs and enhance the services provided by health centres at the village, unit and regional level. Specifically, researchers will endeavor to find out whether SMS ...

STS-48 MS Gemar uses laptop during training session in JSC's MB SMS

Science.gov (United States)

1991-01-01

STS-48 Discovery, Orbiter Vehicle (OV) 103, Mission Specialist (MS) Charles D. Gemar, wearing lightweight headset, enters data into a portable laptop computer on the middeck of JSC's Motion Based (MB) Shuttle Mission Simulator (SMS). Gemar is participating in a preflight familiarization session in the MB-SMS located in the Mission Simulation and Training Facility Bldg 5. Visible to Gemar's right is a stowed extravehicular mobility unit (EMU) and on his left are forward locker mockups.

Symbolic Capital in a Virtual Heterosexual Market: Abbreviation and Insertion in Italian iTV SMS

Science.gov (United States)

Herring, Susan C.; Zelenkauskaite, Asta

2009-01-01

This study analyzes gender variation in nonstandard typography--specifically, abbreviations and insertions--in mobile phone text messages (SMS) posted to a public Italian interactive television (iTV) program. All broadcast SMS were collected for a period of 2 days from the Web archive for the iTV program, and the frequency and distribution of…

Effective Remote Control of Several Outdoor Security Lights by SMS and Wifi Technology

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M. F. Akorede

2017-08-01

Full Text Available The aim of this study was to design and develop a control system using Short Message Service (SMS and wireless networking (WiFi technology to remotely control outdoor security lights in large organisations. The device comprises four main units, namely: the mobile phone or a computer system, the Global System for Mobile communication (GSM modem, the switching unit and the WiFi module. One feature that makes the developed system better than other related existing works is its ability to use two means of control. It makes use of WiFi when the operator is within the coverage area of the network of about 100 m to the device, at no cost, otherwise it uses SMS containing certain codes to control the lights. A Subscriber Identity Module (SIM card is placed in the GSM modem and SMS from the transmitter are sent to that mobile number. The module is also constantly checked by the microcontroller unit, processes the information, extracts the message and command from the GSM modem and WiFi module respectively and then acts accordingly. Owing to its simplicity, C programming is used to programme the microcontroller. The developed device when tested with three lighting points operating on 230V power supply, gives an impressive performance in terms of accuracy and promptness with both SMS and WiFi technology.

Pengaruh pendidikan kesehatan melalui short message service (sms dan booklet tentang obesitas pada remaja overweight dan obesitas

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Usi Lanita

2015-07-01

Full Text Available Background: Adolescent is an important period to be considered because it is a transition period between children and adult. Nutrition problem in an adolescent is while the decline of physical activity, teenage generally have a big appetite, hence, they often look for additional food. The majority of diet that teenage like are an energy dense, sweet, and high-fat foods, which could have a risk of causing overweight and obesity if consumed excessively. Therefore, one of the efforts to overcome the nutrition problem is given a health education to teenage. Objective: To seek for the effect of health education by short message service (SMS and a booklet about obesity on knowledge and body mass index (BMI in an overweight and obese adolescent. Method: This study used a quasi-experiment with pre-test and post-test design. The subject were 105 respondents of overweight and obese senior high school students. The data were analyze used a paired t-test and ANOVA with p=0.05 and CI=95%. Results: Health education by SMS, booklet and the combination of SMS and booklet had a significant effect statistically (p0.05 to reduce BMI in an overweight and obese adolescent. Conclusion: Health education by SMS, booklet, and combination of SMS and booklet have an effect on increasing the knowledge in overweight and obese adolescent, whereas on BMI, only SMS and booklet have an effect on reducing BMI.

Drinking water consumption patterns among adults-SMS as a novel tool for collection of repeated self-reported water consumption.

Science.gov (United States)

Säve-Söderbergh, Melle; Toljander, Jonas; Mattisson, Irene; Åkesson, Agneta; Simonsson, Magnus

2018-03-01

Studies have shown that the average drinking water consumption ranges between 0.075 and 3 L/day for adults with both national and regional differences. For exposure assessment of drinking water hazards, country-specific drinking water consumption data including sources of the consumed water may therefore be warranted. To estimate the amount and source of drinking water consumed among adults in Sweden, we collected self-reported estimates using both traditional methods (telephone interviews, web questionnaire) and a novel method (Short Message Service, SMS questionnaires) in a population from an average sized Swedish municipality. Monthly SMS questionnaires were sent out during one year to obtain longitudinal information as well. SMS showed to be a promising tool for collecting self-reported consumption, as most citizens could participate and the method showed high response rate. Data collected via the SMS questionnaire shows an average consumption of cold tap water of 4.9 glasses/24 h (one glass=200 ml), while the average estimates of cold tap water collected by the traditional methods range from 4.5 to 7.0 glasses/24 h. For statistical distributions, the mean daily consumption of cold tap water for the population was best fitted to a gamma distribution. About 70% of the cold tap water is consumed at home. Based on the results from the SMS study, we suggest using 1 l/day for the average adult population and 2.5 l/day for high consumers for risk assessment of cold tap water consumption. As 46% of the tap water consumed is heated, we suggest using 1.85 l/day for total tap water consumption.

LabPush: a pilot study of providing remote clinics with laboratory results via short message service (SMS in Swaziland, Africa.

Directory of Open Access Journals (Sweden)

Wen-Shan Jian

Full Text Available BACKGROUND: Turnaround time (TAT is an important indicator of laboratory performance. It is often difficult to achieve fast TAT for blood tests conducted at clinics in developing countries. This is because clinics where the patient is treated are often far away from the laboratory, and transporting blood samples and test results between the two locations creates significant delay. Recent efforts have sought to mitigate this problem by using Short Message Service (SMS to reduce TAT. Studies reporting the impact of this technique have not been published in scientific literature however. In this paper we present a study of LabPush, a system developed to test whether SMS delivery of HIV related laboratory results to clinics could shorten TAT time significantly. METHOD: LapPush was implemented in six clinics of the Kingdom of Swaziland. SMS results were sent out from the laboratory as a supplement to normal transport of paper results. Each clinic was equipped with a mobile phone to receive SMS results. The laboratory that processes the blood tests was equipped with a system for digital input of results, and transmission of results via SMS to the clinics. RESULTS: Laboratory results were received for 1041 different clinical cases. The total number of SMS records received (1032 was higher than that of paper records (965, indicating a higher loss rate for paper records. A statistical comparison of TAT for SMS and paper reports indicates a statistically significant improvement for SMS. Results were more positive for more rural clinics, and an urban clinic with high workload. CONCLUSION: SMS can be used to reduce TAT for blood tests taken at clinics in developing countries. Benefits are likely to be greater at clinics that are further away from laboratories, due to the difficulties this imposes on transport of paper records.

The EQ3/6 software package for geochemical modeling: Current status

International Nuclear Information System (INIS)

Worlery, T.J.; Jackson, K.J.; Bourcier, W.L.; Bruton, C.J.; Viani, B.E.; Knauss, K.G.; Delany, J.M.

1988-07-01

EQ3/6 is a software package for modeling chemical and mineralogic interactions in aqueous geochemical systems. The major components of the package are EQ3NR (a speciation-solubility code), EQ6 (a reaction path code), EQLIB (a supporting library), and a supporting thermodynamic data base. EQ3NR calculates aqueous speciation and saturation indices from analytical data. It can also be used to calculate compositions of buffer solutions for use in laboratory experiments. EQ6 computes reaction path models of both equilibrium step processes and kinetic reaction processes. These models can be computed for closed systems and relatively simple open systems. EQ3/6 is useful in making purely theoretical calculations, in designing, interpreting, and extrapolating laboratory experiments, and in testing and developing submodels and supporting data used in these codes. The thermodynamic data base supports calculations over the range 0-300 degree C. 60 refs., 2 figs

The EQ3/6 software package for geochemical modeling: Current status

Energy Technology Data Exchange (ETDEWEB)

Wolery, T.J.; Jackson, K.J.; Bourcier, W.L.; Bruton, C.J.; Viani, B.E.; Knauss, K.G.; Delany, J.M.

1988-07-01

EQ3/6 is a software package for modeling chemical and mineralogic interactions in aqueous geochemical systems. The major components of the package are EQ3NR (a speciation-solubility code), EQ6 (a reaction path code), EQLIB (a supporting library), and a supporting thermodynamic data base. EQ3NR calculates aqueous speciation and saturation indices from analytical data. It can also be used to calculate compositions of buffer solutions for use in laboratory experiments. EQ6 computes reaction path models of both equilibrium step processes and kinetic reaction processes. These models can be computed for closed systems and relatively simple open systems. EQ3/6 is useful in making purely theoretical calculations, in designing, interpreting, and extrapolating laboratory experiments, and in testing and developing submodels and supporting data used in these codes. The thermodynamic data base supports calculations over the range 0-300{degree}C. 60 refs., 2 figs.

Community Land Model Version 3.0 (CLM3.0) Developer's Guide

Energy Technology Data Exchange (ETDEWEB)

Hoffman, FM

2004-12-21

This document describes the guidelines adopted for software development of the Community Land Model (CLM) and serves as a reference to the entire code base of the released version of the model. The version of the code described here is Version 3.0 which was released in the summer of 2004. This document, the Community Land Model Version 3.0 (CLM3.0) User's Guide (Vertenstein et al., 2004), the Technical Description of the Community Land Model (CLM) (Oleson et al., 2004), and the Community Land Model's Dynamic Global Vegetation Model (CLM-DGVM): Technical Description and User's Guide (Levis et al., 2004) provide the developer, user, or researcher with details of implementation, instructions for using the model, a scientific description of the model, and a scientific description of the Dynamic Global Vegetation Model integrated with CLM respectively. The CLM is a single column (snow-soil-vegetation) biogeophysical model of the land surface which can be run serially (on a laptop or personal computer) or in parallel (using distributed or shared memory processors or both) on both vector and scalar computer architectures. Written in Fortran 90, CLM can be run offline (i.e., run in isolation using stored atmospheric forcing data), coupled to an atmospheric model (e.g., the Community Atmosphere Model (CAM)), or coupled to a climate system model (e.g., the Community Climate System Model Version 3 (CCSM3)) through a flux coupler (e.g., Coupler 6 (CPL6)). When coupled, CLM exchanges fluxes of energy, water, and momentum with the atmosphere. The horizontal land surface heterogeneity is represented by a nested subgrid hierarchy composed of gridcells, landunits, columns, and plant functional types (PFTs). This hierarchical representation is reflected in the data structures used by the model code. Biophysical processes are simulated for each subgrid unit (landunit, column, and PFT) independently, and prognostic variables are maintained for each subgrid unit

Proposal and Implementation of An IDS for Potential SMS Spam Signaling Messages on SS7

OpenAIRE

Yeboah, Paul Ntim

2016-01-01

Problem Description Reports on spam activities reaching telecom operators reveal flaws in routing for SMS on the Signaling System 7 network. This thesis consists of the following tasks: A comprehensive Study of vulnerabilities on the SS7 network. Proposal and implementation of an intrusion detection system to mitigate signaling for SMS spam on the SS7 network. Evaluation of the proposed detection method.

Enabling Philippine Farmers to Adapt to Climate Variability Using Seasonal Climate and Weather Forecast with a Crop Simulation Model in an SMS-based Farmer Decision Support System

Science.gov (United States)

Ebardaloza, J. B. R.; Trogo, R.; Sabido, D. J.; Tongson, E.; Bagtasa, G.; Balderama, O. F.

2015-12-01

Corn farms in the Philippines are rainfed farms, hence, it is of utmost importance to choose the start of planting date so that the critical growth stages that are in need of water will fall on dates when there is rain. Most farmers in the Philippines use superstitions and traditions as basis for farming decisions such as when to start planting [1]. Before climate change, superstitions like planting after a feast day of a saint has worked for them but with the recent progression of climate change, farmers now recognize that there is a need for technological intervention [1]. The application discussed in this paper presents a solution that makes use of meteorological station sensors, localized seasonal climate forecast, localized weather forecast and a crop simulation model to provide recommendations to farmers based on the crop cultivar, soil type and fertilizer type used by farmers. It is critical that the recommendations given to farmers are not generic as each farmer would have different needs based on their cultivar, soil, fertilizer, planting schedule and even location [2]. This application allows the farmer to inquire about whether it will rain in the next seven days, the best date to start planting based on the potential yield upon harvest, when to apply fertilizer and by how much, when to water and by how much. Short messaging service (SMS) is the medium chosen for this application because while mobile penetration in the Philippines is as high as 101%, the smart phone penetration is only at 15% [3]. SMS has been selected as it has been identified as the most effective way of reaching farmers with timely agricultural information and knowledge [4,5]. The recommendations while derived from making use of Automated Weather Station (AWS) sensor data, Weather Research Forecasting (WRF) models and DSSAT 4.5 [9], are translated into the local language of the farmers and in a format that is easily understood as recommended in [6,7,8]. A pilot study has been started

IL-3 Maintains Activation of the p90S6K/RPS6 Pathway and Increases Translation in Human Eosinophils.

Science.gov (United States)

Esnault, Stephane; Kelly, Elizabeth A B; Shen, Zhong-Jian; Johansson, Mats W; Malter, James S; Jarjour, Nizar N

2015-09-15

IL-5 is a major therapeutic target to reduce eosinophilia. However, all of the eosinophil-activating cytokines, such as IL-5, IL-3, and GM-CSF, are typically present in atopic diseases, including allergic asthma. As a result of the functional redundancy of these three cytokines on eosinophils and the loss of IL-5R on airway eosinophils, it is important to take IL-3 and GM-CSF into account to efficiently reduce tissue eosinophil functions. Moreover, these three cytokines signal through a common β-chain receptor but yet differentially affect protein production in eosinophils. Notably, the increased ability of IL-3 to induce the production of proteins, such as semaphorin-7A, without affecting mRNA levels suggests a unique influence of IL-3 on translation. The purpose of this study was to identify the mechanisms by which IL-3 distinctively affects eosinophil function compared with IL-5 and GM-CSF, with a focus on protein translation. Peripheral blood eosinophils were used to study intracellular signaling and protein translation in cells activated with IL-3, GM-CSF, or IL-5. We establish that, unlike GM-CSF or IL-5, IL-3 triggers prolonged signaling through activation of ribosomal protein S6 (RPS6) and the upstream kinase 90-kDa ribosomal S6 kinase (p90S6K). Blockade of p90S6K activation inhibited phosphorylation of RPS6 and IL-3-enhanced semaphorin-7A translation. Furthermore, in an allergen-challenged environment, in vivo phosphorylation of RPS6 and p90S6K was enhanced in human airway compared with circulating eosinophils. Our findings provide new insights into the mechanisms underlying differential activation of eosinophils by IL-3, GM-CSF, and IL-5. These observations identify IL-3 and its downstream intracellular signals as novel targets that should be considered to modulate eosinophil functions. Copyright © 2015 by The American Association of Immunologists, Inc.

Photocatalytic activity of Bi{sub 2}WO{sub 6}/Bi{sub 2}S{sub 3} heterojunctions: the facilitation of exposed facets of Bi{sub 2}WO{sub 6} substrate

Energy Technology Data Exchange (ETDEWEB)

Yan, Long [School of Chemistry and Chemical Engineering, Yulin University, Shaanxi Key Laboratory of Low Metamorphic Coal Clean Utilization, Yulin 71900 (China); School of Chemistry and Chemical Engineering, Yan’an University, Shaanxi Key Laboratory of Chemical Reaction Engineering, Yan’an 716000 (China); Wang, Yufei [School of Chemistry and Chemical Engineering, Yulin University, Shaanxi Key Laboratory of Low Metamorphic Coal Clean Utilization, Yulin 71900 (China); Shen, Huidong; Zhang, Yu [School of Chemistry and Chemical Engineering, Yan’an University, Shaanxi Key Laboratory of Chemical Reaction Engineering, Yan’an 716000 (China); Li, Jian [School of Chemistry and Chemical Engineering, Yulin University, Shaanxi Key Laboratory of Low Metamorphic Coal Clean Utilization, Yulin 71900 (China); Wang, Danjun, E-mail: yulyanlong@aliyun.com [School of Chemistry and Chemical Engineering, Yan’an University, Shaanxi Key Laboratory of Chemical Reaction Engineering, Yan’an 716000 (China)

2017-01-30

Highlights: • Bi{sub 2}S{sub 3}/Bi{sub 2}WO{sub 6} hybrids with exposed (020) Bi{sub 2}WO{sub 6} facets have been synthesized. • X-ray photoelectron spectroscopy reveals that a small amount of Bi{sub 2}S{sub 3} was formed. • The enhanced photoactivity of hybrids is due to heterojunction and (020) facets. • A possible photocatalytic degradation mechanism is proposed. - Abstract: Bi{sub 2}S{sub 3}/Bi{sub 2}WO{sub 6} hybrid architectures with exposed (020) Bi{sub 2}WO{sub 6} facets have been synthesized via a controlled anion exchange approach. X-ray photoelectron spectroscopy (XPS) reveals that a small amount of Bi{sub 2}S{sub 3} was formed on the surface of Bi{sub 2}WO{sub 6} during the anion exchange process, thus leading to the transformation from the Bi{sub 2}WO{sub 6} to Bi{sub 2}S{sub 3}/Bi{sub 2}WO{sub 6}. A rhodamine B (RhB) aqueous solution was chosen as model organic pollutants to evaluate the photocatalytic activities of the Bi{sub 2}S{sub 3}/Bi{sub 2}WO{sub 6} catalysts. Under visible light irradiation, the Bi{sub 2}S{sub 3}/Bi{sub 2}WO{sub 6}-TAA displayed the excellent visible light photoactivities compared with pure Bi{sub 2}S{sub 3}, Bi{sub 2}WO{sub 6} and other composite photocatalysts. The efficient photocatalytic activity of the Bi{sub 2}S{sub 3}/Bi{sub 2}WO{sub 6}-TAA composite microspheres was ascribed to the constructed heterojunctions and the inner electric field caused by the exposed (020) Bi{sub 2}WO{sub 6} facets. Active species trapping experiments revealed that h{sup +} and O{sub 2}·{sup −} are the main active species in the photocatalytic process. Furthermore, the as-obtained photocatalysts showed good photocatalytic activity after four recycles. The results presented in this study provide a new concept for the rational design and development of highly efficient photocatalysts.

STS-44 Atlantis, OV-104, crewmembers participate in FB-SMS training at JSC

Science.gov (United States)

1991-01-01

STS-44 Atlantis, Orbiter Vehicle (OV) 104, Commander Frederick D. Gregory (left) and Pilot Terence T. Henricks, positioned at their appointed stations on the forward flight deck, are joined by Mission Specialist (MS) F. Story Musgrave (center) and MS James S. Voss (standing). The crewmembers are participating in a flight simulation in the Fixed Base (FB) Shuttle Mission Simulator (SMS) located in JSC's Mission Simulation and Training Facility Bldg 5. A maze of panel switches appear overhead and in the background.

Denni Algorithm An Enhanced Of SMS (Scan, Move and Sort) Algorithm

Science.gov (United States)

Aprilsyah Lubis, Denni; Salim Sitompul, Opim; Marwan; Tulus; Andri Budiman, M.

2017-12-01

Sorting has been a profound area for the algorithmic researchers, and many resources are invested to suggest a more working sorting algorithm. For this purpose many existing sorting algorithms were observed in terms of the efficiency of the algorithmic complexity. Efficient sorting is important to optimize the use of other algorithms that require sorted lists to work correctly. Sorting has been considered as a fundamental problem in the study of algorithms that due to many reasons namely, the necessary to sort information is inherent in many applications, algorithms often use sorting as a key subroutine, in algorithm design there are many essential techniques represented in the body of sorting algorithms, and many engineering issues come to the fore when implementing sorting algorithms., Many algorithms are very well known for sorting the unordered lists, and one of the well-known algorithms that make the process of sorting to be more economical and efficient is SMS (Scan, Move and Sort) algorithm, an enhancement of Quicksort invented Rami Mansi in 2010. This paper presents a new sorting algorithm called Denni-algorithm. The Denni algorithm is considered as an enhancement on the SMS algorithm in average, and worst cases. The Denni algorithm is compared with the SMS algorithm and the results were promising.

A Low-cost Vehicle Tracking Platform using Secure SMS

DEFF Research Database (Denmark)

Jacobsen, Rune Hylsberg; Aliu, Drini; Ebeid, Emad Samuel Malki

2017-01-01

as the in-vehicle device. Furthermore, a cloud web-platform is built involving the de-facto modern web-applications standards and carefully tailored concerning the security aspects. The cost-effectiveness of our solution results from the use of COTS components, open source software, and cheap SMS...

Figures6&7_Tables2&3

Data.gov (United States)

U.S. Environmental Protection Agency — This file contains three netCDF formatted files containing simulation model results used to produce Figures 6 and 7 and tables 3 and 4. These data can be accessed...

Modelling of time delay of electrical breakdown for nitrogen-filled tubes at pressures of 6.6 and 13.3 mbar in the increase region of the memory curve

International Nuclear Information System (INIS)

Nesic, N T; Ristic, G S; Pejovic, M M; Karamarkovic, J P

2008-01-01

Experimentally measured electrical breakdown time delay data versus the afterglow period (representing 'memory curves') for nitrogen-filled tubes at pressures of 6.6 and 13.3 mbar have been shown. The influence of N( 4 S) nitrogen atoms on secondary electron emission from the cathode (the SEE process) in late afterglow has been discussed. N( 4 S) atom concentration decay over relaxation time τ, N( 4 S)(τ), has been analysed by a numerical model and two analytical models. N( 4 S) decay analytical models are combined with different yield models that describe the SEE process by N( 4 S) and these combinations are employed to fit the experimental data. It has been shown that in late afterglow solving of very simple analytical equations instead of numerical solving of partial differential equations for N( 4 S)(τ) fitting can be used and that the combination of the first and the second order of the SEE process by N( 4 S) in yield modelling should be used in the case of 13.3 mbar pressure.

Text Messaging (SMS) Helping Cancer Care in Patients Undergoing Chemotherapy Treatment: a Pilot Study.

Science.gov (United States)

Rico, Timóteo Matthies; Dos Santos Machado, Karina; Fernandes, Vanessa Pellegrini; Madruga, Samanta Winck; Noguez, Patrícia Tuerlinckx; Barcelos, Camila Rose Guadalupe; Santin, Mateus Madail; Petrarca, Cristiane Rios; Dumith, Samuel Carvalho

2017-10-09

Cancer treatment is an extremely stressful life experience that is accompanied by a range of psychological, social, physical, and practical difficulties. Cancer patients need to receive information that helps them to better understand the disease, assists them in decision-making, and helps them deal with treatment. Patients are interested in receiving such information. The degree of satisfaction with the information received has been associated with positive health outcomes, specifically regarding quality of life, severity of side effects, and psychological well-being. This study investigates a method of guiding cancer patients, in relation to outpatient chemotherapy treatment, using SMS (short message service) text messaging. A smartphone application called cHEmotHErApp was developed, and its primary function is to send out SMS text messages with guidance for self-care and emotional support for oncology patients undergoing chemotherapy. Thus, the main objective of this study is to evaluate the acceptance and perception of patients of the receipt of these SMS messages, as well as to evaluate the possible benefits reported by the participants. Adult patients diagnosed with cancer, who started the first outpatient chemotherapy treatment scheme between August and November 2016 at the School Hospital (HE) of the Federal University of Pelotas (UFPel), were invited to participate in this pilot study. In total, 14 cancer patients were adherent to this study. Each of these patients received a daily text message on their cell phone with some guidance on encouraging self-care and emotional support. Patients reported that, because of the SMS text messages they received, they felt more confident in their treatment, felt more supported and encouraged, and that the text messages facilitated self-care. In addition, patients reported that the SMS text messages they received helped them to take better care of themselves and to continue further treatment.

Analisis Isi SMS Iklan Layanan Telekomunikasi Operator Telkomsel, Indosat dan Xl berdasarkan Etika Pariwara Indonesia Periode 2013

Directory of Open Access Journals (Sweden)

Danang Trijayanto

2014-09-01

Full Text Available Perkembangan teknologi komunikasi merevolusi aktivitas pemasaran ke mobile marketing, salah satunya adalah dengan SMS advertising. Badan usaha yang cenderung menggunakan cara pemasaran tersebut adalah operator selular dengan iklan produk layanan telekomunikasinya. Permasalahannya adalah strategi pemasaran produk telekomunikasi yang cenderung banyak merugikan pelanggan karena ketidaksesuaian antara isi iklan dan produk yang diperoleh, yang dipengaruhi oleh kelengkapan dan kejelasan informasi produk. Salah satu aturan yang menjadi dasar dalam aktivitas SMS advertising adalah berdasarkan Etika Pariwara Indonesia.  Penelitian  ini   meneliti  bagaimanakah  Penerapan aturan tersebut terhadap isi SMS iklan produk telekomunikasi yang dikirimkan oleh provider selular GSM prabayar pada bulan Juli hingga Nopember 2013.  Hasil  Penelitian menunjukkan bahwa dalam mengiklankan produk telekomunikasi melalui SMS advertising, para operator selular belum menerapkan regulasi dan etika pemasaran dengan baik. Kekurangan informasi yang belum lengkap terdapat pada informasi syarat kontrak yang menjadi informasi dasar hak dan kewajiban yang harus dipenuhi oleh pelanggan.

Exploring bi-directional and SMS messaging for communications between Public Health Agencies and their stakeholders: a qualitative study.

Science.gov (United States)

Revere, Debra; Calhoun, Rebecca; Baseman, Janet; Oberle, Mark

2015-07-08

dichotomous variables of 0 or 1 on a per respondent basis to enumerate the presence or absence of each thematic code, enable quantitative analysis, and inform interpretation of findings. Five major themes emerged from synthesizing survey and interview results: 1) Regardless of situational context (emergency vs. non-urgent) and message recipient (stakeholder group), e-mail is a favored modality for receiving public health messages; 2) The decision to use bi-directional, SMS or multiple communication strategies is complex and public health agencies' need to manage messaging concerns/barriers and benefits for all parties; 3) Both public health agencies and their stakeholders share similar values/uses and concerns regarding two-way public health messaging and SMS; 4) Public health is highly trusted, thus thoughtful, effective messaging will ensure continuation of this goodwill; and 5) Information reciprocity between public health agencies and stakeholders who share their information is essential. Multiple communication strategies might be utilized but the choice of a specific strategy needs to balance message content (emergency vs. routine communications), delivery (one- vs. two-way), channel (SMS, email, etc.), and public health agency burden with stakeholder preferences and technical capabilities, all while mitigating the risk of message overload and disregard of important communications by recipients.

An efficient conversion of (3R,3'R,6'R)-lutein to (3R,3'S,6'R)-lutein (3'-epilutein) and (3R,3'R)-zeaxanthin.

Science.gov (United States)

Khachik, Frederick

2003-01-01

Two dietary carotenoids, (3R,3'R,6'R)-lutein (1) and (3R,3'R)-zeaxanthin (2), and their metabolite (3R,3'S,6'R)-lutein (3'-epilutein) (3) accumulate in human serum, milk, and ocular tissues. There is increasing evidence that compounds 1 and 2 play an important role in the prevention of age-related macular degeneration. Therefore, the availability of these carotenoids for metabolic studies and clinical trials is essential. Compound 1 is isolated from extracts of marigold flowers (Tagete erecta) and is commercially available, whereas 2 is only accessible by a lengthy total synthesis, and a viable method for synthesis of 3 has not yet been developed. This report describes an efficient conversion of technical grade 1 to 2 via 3. Acid-catalyzed epimerization of 1 yields an equimolar mixture of diastereomers 1 and 3. The mixture was separated by enzyme-mediated acylation with lipase AK from Pseudomonas fluorescens that preferentially esterified 3 and after alkaline hydrolysis yielded this carotenoid in 90% diastereomeric excess (de). Compound 3 was also separated from 1 in 56-88% de by solvent extraction and low-temperature crystallization, Soxhlet extraction, or supercritical fluid extraction. Base-catalyzed isomerization of 3 gave 2 in excellent yield, providing a convenient alternative to the total synthesis of this important dietary carotenoid.

DYSFUNCTIONAL KYNURENINE PATHWAY METABOLISM IN THE R6/2 MOUSE MODEL OF HUNTINGTON’S DISEASE

Science.gov (United States)

Sathyasaikumar, Korrapati V.; Stachowski, Erin K.; Amori, Laura; Guidetti, Paolo; Muchowski, Paul J.; Schwarcz, Robert

2013-01-01

Elevated concentrations of neurotoxic metabolites of the kynurenine pathway (KP) of tryptophan degradation may play a causative role in Huntington’s disease (HD). The brain levels of one of these compounds, 3-hydroxykynurenine (3-HK), are increased in both HD and several mouse models of the disease. In the present study, we examined this impairment in greater detail using the R6/2 mouse, a well-established animal model of HD. Initially, mutant and age-matched wild-type mice received an intrastriatal injection of 3H-tryptophan to assess the acute, local de novo production of kynurenine, the immediate bioprecursor of 3-HK, in vivo. No effect of genotype was observed between 4 and 12 weeks of age. In contrast, intrastriatally applied 3H-kynurenine resulted in significantly increased neosynthesis of 3H-3-HK, but not other tritiated KP metabolites, in the R6/2 striatum. Subsequent ex vivo studies in striatal, cortical and cerebellar tissue revealed substantial increases in the activity of the biosynthetic enzyme of 3-HK, kynurenine 3-monooxygenase (KMO) and significant reductions in the activity of its degradative enzyme, kynureninase, in HD mice starting at 4 weeks of age. Decreased kynureninase activity was most evident in the cortex and preceded the increase in KMO activity. The activity of other KP enzymes showed no consistent brain abnormalities in the mutant mice. These findings suggest that impairments in its immediate metabolic enzymes jointly account for the abnormally high brain levels of 3-HK in the R6/2 model of HD. PMID:20236387

The effectiveness of SMS Reminders and the impact of patient characteristics on missed appointments in a public dental outpatient clinic

Directory of Open Access Journals (Sweden)

Emilia Bellucci

2017-03-01

Full Text Available This paper reports on the Failure To Attend (FTA rate of appointments as well as patients following the implementation of SMS reminders in a public dental outpatient service.  Given the ineffectiveness of the intervention and a highly representative patient’s profile, this paper identifies the demographic characteristics of patients who miss all of their appointments.  Data on appointment attendance, patient demographics and dental service type was collected over a time period of 46 consecutive months.  Using descriptive and inferential statistics (chi-square, two sample tests and Marascuilo procedure we found the SMS intervention was ineffective in reducing the FTA rates. Further, patients associated with high rates of non-attendance exhibited one or more of the following characteristics: male; age 26 – 44; non-concession card holders; a person of Indigenous, local, Asian or African descent, and of refugee status, persons living in low socio-economic areas; and appointments in General Care and Student Clinics. Whilst the literature overwhelmingly attributes SMS reminders to improving the attendance rate of patients in outpatient clinics, our contradictory findings suggest a more targeted approach in settings whose patients exhibit strong characteristics associated with non-attendance.

STS-31 crewmembers during simulation on the flight deck of JSC's FB-SMS

Science.gov (United States)

1988-01-01

On the flight deck of JSC's fixed based (FB) shuttle mission simulator (SMS), Mission Specialist (MS) Steven A. Hawley (left), on aft flight deck, looks over the shoulders of Commander Loren J. Shriver, seated at the commanders station (left) and Pilot Charles F. Bolden, seated at the pilots station and partially blocked by the seat's headrest (right). The three astronauts recently named to the STS-31 mission aboard Discovery, Orbiter Vehicle (OV) 103, go through a procedures checkout in the FB-SMS. The training simulation took place in JSC's Mission Simulation and Training Facility Bldg 5.

Text message-based diabetes self-management support (SMS4BG): study protocol for a randomised controlled trial.

Science.gov (United States)

Dobson, Rosie; Whittaker, Robyn; Jiang, Yannan; Shepherd, Matthew; Maddison, Ralph; Carter, Karen; Cutfield, Richard; McNamara, Catherine; Khanolkar, Manish; Murphy, Rinki

2016-04-02

Addressing the increasing prevalence, and associated disease burden, of diabetes is a priority of health services internationally. Interventions to support patients to effectively self-manage their condition have the potential to reduce the risk of costly and debilitating complications. The utilisation of mobile phones to deliver self-management support allows for patient-centred care at the frequency and intensity that patients desire from outside the clinic environment. Self-Management Support for Blood Glucose (SMS4BG) is a novel text message-based intervention for supporting people with diabetes to improve self-management behaviours and achieve better glycaemic control and is tailored to individual patient preferences, demographics, clinical characteristics, and culture. This study aims to assess whether SMS4BG can improve glycaemic control in adults with poorly controlled diabetes. This paper outlines the rationale and methods of the trial. A two-arm, parallel, randomised controlled trial will be conducted across New Zealand health districts. One thousand participants will be randomised at a 1:1 ratio to receive SMS4BG, a theoretically based and individually tailored automated text message-based diabetes self-management support programme (intervention) in addition to usual care, or usual care alone (control). The primary outcome is change in glycaemic control (HbA1c) at 9 months. Secondary outcomes include glycaemic control at 3 and 6 months, self-efficacy, self-care behaviours, diabetes distress, health-related quality of life, perceived social support, and illness perceptions. Cost information and healthcare utilisation will also be collected as well as intervention satisfaction and interaction. This study will provide information on the effectiveness of a text message-based self-management support tool for people with diabetes. If found to be effective it has the potential to provide individualised support to people with diabetes across New Zealand (and

Locating Mobility: Practices of co-presence and the persistence of the postal metaphor in SMS/ MMS mobile phone customization in Melbourne

Directory of Open Access Journals (Sweden)

Larissa Hjorth

2005-01-01

Full Text Available One of the marked features of ICT’s (Information and Communication Technologies mobility (literal and electronic is the role of customization in location (Castells, 2001; Manovich, 2001. When we think of "customizing" mobile phones we often summon up an image of techno-savvy places such as Tokyo where the outside of the mobile phone (keitai is adorned with a plethora of cute (kawaii characters in, for example, the style of Hello Kitty. Indeed, much of the Asia-Pacific region seems characterized by seemingly every form of mobile phone adornment. One could be mistaken, then, for thinking that Melbourne is out of place in the mobile flows of the region. However, Melbourne demonstrates that customization can also occur inside the mobile phone. Customization is not just a matter of wallpapers and ringtones. It is also the case that customizing of applications such as SMS (Short Message Service speaks of specific processes of subjectivity, cultural capital (Bourdieu, 1984[1979]; McVeigh, 2003 and locality (Massey, 1993. Such internal customization operates as an important mode for users to become active producers in the extension of conventions of the emerging genre.Once just an application used for its simplicity and affordability, SMS has grown to be an enduring mode of mobile phone communication (Goggin, 2004. The resilience and evolution of SMS practices has resulted in it surpassing the role of a "making-do" application; SMS has grown to accommodate particular modes of etiquette and to signify gestures of intimacy. I argue that SMS customization is central to a personalizing and localizing of remediated technologies (Bolter and Grusin, 1999 that is best understood as a persistence of the postal metaphor. As a remediated genre reminiscent of such genres as the 18th century visiting card (Milne, 2004, SMS and its practices of co-presence need to be understood in terms of earlier genres of telepresence and intimacy . In order to discuss some of

Short message service (SMS) language and written language skills ...

African Journals Online (AJOL)

SMS language is English language slang, used as a means of mobile phone text messaging. This practice may impact on the written language skills of learners at school. The main aim of this study was to determine the perspectives of Grade 8 and 9 English (as Home Language) educators in Gauteng regarding the ...

PAIN IN A PARKINSON`S DISEASE RODENT ANIMAL MODEL INDUCED WITH 6-HYDROXYDOPAMINE

Directory of Open Access Journals (Sweden)

Antioch, I

2017-06-01

Full Text Available Pain phenomenon, the unpleasant sensory and emotional event, appears to evidently intrude in Parkinson disease (PD, a disease formally considered to be restricted only to motor deficits. Although over a half of persons with PD suffer from pain manifestations, there are very few reports targeting this issue. Considering the cases when motor symptoms of PD are eclipsed by severe pain disclosure, there is an obvious need of clarifying the intricate implications of pain in PD context. Because there are few studies researching the link between pain and PD in clinical context, but as well in animal models we chose to explore the effects of pain stimuli on a rodent model of PD. Materials and methods: We experimentally induced a PD model in Wistar rats (n=12 by injecting in the substantia nigra, a brain area known to be involved in PD occurrence, one dose of a 6-hydroxidopamine (6-OHDA solution (8µm 6-OHDA base and 4µm physiological saline, utilizing neurosurgery, while their control peers received same dose of saline solution. Two weeks after the intervention the animals were subjected to the hot-plate test, a behavioral task for acquiring pain sensitivity. Results: There was noticed a statistical significant (F(1,10 = 5.67, p=0.038 sensibility of the 6-OHDA rats to thermal pain stimuli (8.2 s ± 0.8 s in 6-OHDA group as compared to their peers (13.8 s ± 1.6 s in controls. Conclusions: The involvement of pain in PD animal models is demonstrated raising questions of how it influences PD evolution. Moreover, this result increases awareness of deficient diagnostic methods of pain in PD and as a consequence, poor treatment of pain manifestations.

IL-3 maintains activation of the P90S6K/RPS6 pathway and increases translation in human eosinophils1

Science.gov (United States)

Esnault, Stephane; Kelly, Elizabeth A.B.; Shen, Zhong-Jian; Johansson, Mats W.; Malter, James S.; Jarjour, Nizar N.

2015-01-01

IL-5 is a major therapeutic target to reduce eosinophilia. However, all of the eosinophil-activating cytokines IL-5, IL-3, and GM-CSF are typically present in atopic diseases including allergic asthma. Due to the functional redundancy of these 3 cytokines on eosinophils and the loss of IL-5 receptor on airway eosinophils, it is important to take IL-3 and GM-CSF into account to efficiently reduce tissue eosinophil functions. Moreover, these 3 cytokines signal through a common β-chain receptor, and yet differentially affect protein production in eosinophils. Notably, the increased ability of IL-3 to induce production of proteins such as semaphorin-7A without affecting mRNA level suggests a unique influence by IL-3 on translation. The purpose of this study is to identify the mechanisms by which IL-3 distinctively affects eosinophil function compared to IL-5 and GM-CSF, with a focus on protein translation. Peripheral blood eosinophils were used to study intracellular signaling and protein translation in cells activated with IL-3, GM-CSF or IL-5. We establish that, unlike GM-CSF or IL-5, IL-3 triggers prolonged signaling through activation of ribosomal protein (RP) S6 and the upstream kinase, p90S6K. Blockade of p90S6K activation inhibited phosphorylation of RPS6 and IL-3-enhanced semaphorin-7A translation. Furthermore, in an allergen-challenged environment, in vivo phosphorylation of RPS6 and p90S6K was enhanced in human airway compared to circulating eosinophils. Our findings provide new insights into the mechanisms underlying differential activation of eosinophils by IL-3, GM-CSF, and IL-5. These observations place IL-3 and its downstream intracellular signals as novel targets that should be considered to modulate eosinophil functions. PMID:26276876

Consumer acceptance of an SMS-assisted smoking cessation intervention: a multicountry study.

Science.gov (United States)

Andrews, Lynda; Cacho-Elizondo, Silvia; Drennan, Judy; Tossan, Vessélina

2013-01-01

This study assesses smokers' perceptions, motivations, and intentions towards using an SMS-assisted smoking cessation intervention in Australia, France, and Mexico through an extended technology acceptance model with mediating variables. Data was collected through online surveys. Results show that perceived usefulness and vicarious innovativeness predict use intentions for all three countries. Perceived ease of use is significant only for Mexico. Subjective norms are significant only for Mexico and Australia. Perceived monetary value and perceived annoyance are significant mediating variables for all three countries, whereas perceived enjoyment is significant only for Mexico and Australia. These results contribute to theory and practice.

23 CFR 973.212 - Indian lands safety management system (SMS).

Science.gov (United States)

2010-04-01

... implementation of public information and education activities on safety needs, programs, and countermeasures... 23 Highways 1 2010-04-01 2010-04-01 false Indian lands safety management system (SMS). 973.212... HIGHWAYS MANAGEMENT SYSTEMS PERTAINING TO THE BUREAU OF INDIAN AFFAIRS AND THE INDIAN RESERVATION ROADS...

SISTEM PEMESANAN KAMAR RAWAT INAP MENGGUNAKAN SHORT MESSAGE SERVICES (SMS PADA RUMAH SAKIT

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Beny Irawan

2016-01-01

Full Text Available Abstrak – Manusia hidup di dunia ada bermacam-macam bentuk tubuh, besar, kecil, tua-muda, laki-laki, perempuan, bentuk muka, warna kulit atau kondisi fisiknya ada yang sehat dan sakit. Semakin bertambahnya manusia di alam ini, semakin banyak persentase kemungkinan orang mengalami sakit mendadak, sehingga membutuhkan perawatan medis yang mendadak juga. Untuk itu, diperlukan suatu cara yang paling mudah untuk melakukan konfirmasi ada atau tidaknya kamar untuk rawat inap di rumah sakit yang bersangkutan, sehingga pasien tidak harus melakukan pemesanan kamar ketika sudah tiba di rumah sakit yang bersangkutan, dan kemudian semua kamar sudah penuh dan harus dipindahkan lagi ke rumah sakit lain. Hal ini menyebabkan si pasien akan mengalami keterlambatan untuk ditangani, sehingga bisa berakibat fatal bagi pasien tersebut. Permasalahan tersebut dapat ditangani dengan pengembangan sistem baru menggunakan short message services (sms terutama untuk pemesanan kamar rawat inap, dan untuk mengetahui jenis pelayanan lain yang ada di rumah sakit tersebut melalui website rumah sakit, sehingga sistem pemesanan kamar semakin efektif dan efisien. Namun, sistem yang dikembangkan masih memiliki kelemahan karena sistem hanya dapat digunakan pada telepon selular yang menggunakan modem GSM.   Keywords : Short Message Service (SMS, SMS Gateway, GSM

Model for Microcapsule Drug Release with Ultrasound-Activated Enhancement.

Science.gov (United States)

Tsao, Nadia H; Hall, Elizabeth A H

2017-11-14

Microbubbles and microcapsules of silane-polycaprolactone (SiPCL) have been filled with a fluorescent acridium salt (lucigenin) as a model for a drug-loaded delivery vehicle. The uptake and delivery were studied and compared with similar microbubbles and microcapsules of silica/mercaptosilica (S/M/S). Positively charged lucigenin was encapsulated through an electrostatic mechanism, following a Type I Langmuir isotherm as expected, but with an additional multilayer uptake that leads to a much higher loading for the SiPCL system (∼280 μg/2.4 × 10 9 microcapsules compared with ∼135 μg/2.4 × 10 9 microcapsules for S/M/S). Whereas the lucigenin release from the S/M/S bubbles and capsules loaded below the solubility limit is consistent with diffusion from a monolithic structure, the SiPCL structures show distinct release patterns; the Weibull function predicts a general trend for diffusion from normal Euclidean space at short times tending toward diffusion out of fractal spaces with increasing time. As a slow release system, the dissolution time (T d ) increases from 1 to 2 days for the S/M/S and for the low concentration, loaded SiPCl vehicles to ∼10 days for the high loaded microcapsules. However, T d can be reduced on insonation to 2 days, indicating the potential to gain control over the local enhanced release with ultrasound. This was tested for a docetaxel model and its effect on C4-2B prostate cancer cells, showing improved cell toxicity for concentrations below the normal EC 50 in solution.

The simplified models approach to constraining supersymmetry

Energy Technology Data Exchange (ETDEWEB)

Perez, Genessis [Institut fuer Theoretische Physik, Karlsruher Institut fuer Technologie (KIT), Wolfgang-Gaede-Str. 1, 76131 Karlsruhe (Germany); Kulkarni, Suchita [Laboratoire de Physique Subatomique et de Cosmologie, Universite Grenoble Alpes, CNRS IN2P3, 53 Avenue des Martyrs, 38026 Grenoble (France)

2015-07-01

The interpretation of the experimental results at the LHC are model dependent, which implies that the searches provide limited constraints on scenarios such as supersymmetry (SUSY). The Simplified Models Spectra (SMS) framework used by ATLAS and CMS collaborations is useful to overcome this limitation. SMS framework involves a small number of parameters (all the properties are reduced to the mass spectrum, the production cross section and the branching ratio) and hence is more generic than presenting results in terms of soft parameters. In our work, the SMS framework was used to test Natural SUSY (NSUSY) scenario. To accomplish this task, two automated tools (SModelS and Fastlim) were used to decompose the NSUSY parameter space in terms of simplified models and confront the theoretical predictions against the experimental results. The achievement of both, just as the strengths and limitations, are here expressed for the NSUSY scenario.

Quasimolecular emission near the Xe(5p 56s 1,3 P 1 - 5p 6 1 S 0) and Kr (4p 55s 1,3 P 1 - 4p 6 1 S 0) resonance lines induced by collisions with He atoms

Science.gov (United States)

Alekseeva, O. S.; Devdariani, A. Z.; Grigorian, G. M.; Lednev, M. G.; Zagrebin, A. L.

2017-02-01

This study is devoted to the theoretical investigation of the quasimolecular emission of Xe*-He and Kr*-He collision pairs near the Xe (5p 56s 1,3 P 1 - 5p 6 1 S 0) and Kr (4p 55s 1,3 P 1 - 4p 6 1 S 0) resonance atomic lines. The potential curves of the quasimolecules Xe(5p 56s) + He and Kr(4p 55s) + He have been obtained with the use of the effective Hamiltonian and pseudopotential methods. Based on these potential curves the processes of quasimolecular emission of Xe*+He and Kr*+He mixtures have been considered and the spectral distributions I(ħΔω) of photons emitted have been obtained in the framework of quasistatic approximation.

Linking at-risk South African girls to sexual violence and reproductive health services: A mixed-methods assessment of a soccer-based HIV prevention program and pilot SMS campaign.

Science.gov (United States)

Merrill, Katherine G; Merrill, Jamison C; Hershow, Rebecca B; Barkley, Chris; Rakosa, Boitumelo; DeCelles, Jeff; Harrison, Abigail

2018-04-30

Grassroot Soccer developed SKILLZ Street-a soccer-based life skills program with a supplementary SMS platform-to support adolescent girls at risk for HIV, violence, and sexual and reproductive health challenges. We conducted a mixed-methods assessment of preliminary outcomes and implementation processes in three primary schools in Soweto, South Africa, from August to December 2013. Quantitative methods included participant attendance and SMS platform usage tracking, pre/post questionnaires, and structured observation. Qualitative data were collected from program participants, parents, teachers, and a social worker during 6 focus group discussions and 4 in-depth interviews. Of 394 participants enrolled, 97% (n = 382) graduated, and 217 unique users accessed the SMS platform. Questionnaires completed by 213 participants (mean age: 11.9, SD: 3.02 years) alongside qualitative findings showed modest improvements in participants' perceptions of power in relationships and gender equity, self-esteem, self-efficacy to avoid unwanted sex, communication with others about HIV and sex, and HIV-related knowledge and stigma. The coach-participant relationship, safe space, and integration of soccer were raised as key intervention components. Implementation challenges were faced around delivery of soccer-based activities. Findings highlight the relevance and importance of programs like SKILLZ Street in addressing challenges facing adolescent girls in South African townships. Recommendations for future programs are provided. Copyright © 2018 Elsevier Ltd. All rights reserved.

OPTIMALISASI GITHUB UNTUK SOFTWARE PROJECT MANAGEMENT DENGAN MEMANFAATKAN NOTIFIKASI SMS

Directory of Open Access Journals (Sweden)

Syarif Hidayatulloh

2016-03-01

Full Text Available Abstract - software project management is the art and science of planning and supervision in software projects. On project management software many emerging constraints that could result in his development and software development. One of the key points in a project the software repository is the time it takes to comment on, add and merge source code. Rapid feedback to make the members of a software project team was pleased to contribute in a software project. Problems on Github repository is when the notification was delivered via the web and email are not directly addressed because the members of the project management software rarely check emails. The methods used in this study is a literature study and experiments of different cases in the article, book or paper that discusses how to implement project management software quality so the software project goals can be achieved. Conclusion the results of the research that has been done is to apply the SMS notification on Github is expected to further speed up the interaction and communication between members in a software project and makes it easier for an IT manager in conducting management on Github project. Keywords: Software project management, GitHub, notification, SMS Abstrak - Manajemen proyek Perangkat lunak adalah seni dan ilmu perencanaan dan pembimbingan dalam proyek perangkat lunak. Pada manajemen proyek perangkat lunak banyak muncul kendala-kendala yang dapat mengakibatkan lamanya pembangunan dan pengembangan perangkat lunak. Salah satu poin penting dalam sebuah repositori proyek perangkat lunak adalah waktu yang dibutuhkan untuk mengomentari, menambahkan dan menggabungkan source code. Feedback yang cepat membuat anggota-anggota tim proyek perangkat lunak merasa senang untuk berkontribusi dalam sebuah proyek perangkat lunak. Permasalahan pada repositori Github adalah ketika notifikasi yang disampaikan lewat web dan email tidak langsung ditanggapi karena anggota-anggota proyek

Simultaneous multislice triple-echo steady-state (SMS-TESS) T1 , T2 , PD, and off-resonance mapping in the human brain.

Science.gov (United States)

Heule, Rahel; Celicanin, Zarko; Kozerke, Sebastian; Bieri, Oliver

2018-02-21

To investigate the ability of simultaneous multislice triple-echo steady-state (SMS-TESS) imaging to provide quantitative maps of multiple tissue parameters, i.e., longitudinal and transverse relaxation times (T 1 and T 2 ), proton density (PD), and off-resonance (ΔB 0 ), in the human brain at 3T from a single scan. TESS acquisitions were performed in 2D mode to reduce motion sensitivity and accelerated by an SMS excitation scheme (CAIPIRINHA) with SENSE reconstruction. SMS-acceleration factors (R) of 2 and 4 were evaluated. The in vitro and in vivo validation process included standard reference scans to analyze the accuracy of T 1 , T 2 , and ΔB 0 estimates, as well as single-slice TESS measurements. For R = 2, the quantification of T 1 , T 2 , PD, and ΔB 0 was overall reliable with marginal noise enhancement. T 1 and T 2 values were in good agreement with the reference measurements and single-slice TESS. For R = 4, the agreement of ΔB 0 with the standard reference was excellent and the determination of T 1 , T 2 , and PD was reproducible; however, increased variations in T 1 and T 2 values with respect to single-slice TESS were observed. SMS-TESS has shown potential to offer rapid simultaneous T 1 , T 2 , PD, and ΔB 0 mapping of human brain tissues. © 2018 International Society for Magnetic Resonance in Medicine.

The effect of distance learning via SMS on academic achievement and satisfaction of medical students.

Science.gov (United States)

Sichani, Mehrdad Mohammadi; Mobarakeh, Shadi Reissizadeh; Omid, Athar

2018-01-01

Recently, medical education has made significant progress, and medical teachers are trying to find methods that have most impressive effects on learning. One of the useful learning methods is student active participation. One of the helpful teaching aids in this method is mobile technology. The present study aimed to determine the effect of sending educational questions through short message service (SMS) on academic achievement and satisfaction of medical students and compare that with lecture teaching. In an semi-experimental, two chapters of urology reference book, Smiths General Urology 17 th edition, were taught to 47 medical students of Isfahan University of Medical Sciences in urology course in 2013 academic year. Kidney tumors chapter was educated by sending questions through SMS, and bladder tumors part was taught in a lecture session. For each method, pretest and posttest were held, each consisting of thirty multiple choice questions. To examine the knowledge retention, a test session was held on the same terms for each chapter, 1 month later. At the end, survey forms were distributed to assess student's satisfaction with SMS learning method. Data were analyzed through using SPSS 20. The findings demonstrated a statistically significant difference between the two learning methods in the medication test scores. Evaluation of the satisfaction showed 78.72% of participants were not satisfied. The results of the study showed that distance learning through SMS in medical students could lead to increase knowledge, however, it was not effective on their satisfaction.

Temperature studies of optical parameters of (Ag3AsS3)0.6(As2S3)0.4 thin films prepared by rapid thermal evaporation and pulse laser deposition

Science.gov (United States)

Studenyak, I. P.; Kutsyk, M. M.; Buchuk, M. Yu.; Rati, Y. Y.; Neimet, Yu. Yu.; Izai, V. Yu.; Kökényesi, S.; Nemec, P.

2016-02-01

(Ag3AsS3)0.6(As2S3)0.4 thin films were deposited using rapid thermal evaporation (RTE) and pulse laser deposition (PLD) techniques. Ag-enriched micrometre-sized cones (RTE) and bubbles (PLD) were observed on the thin film surface. Optical transmission spectra of the thin films were studied in the temperature range 77-300 K. The Urbach behaviour of the optical absorption edge in the thin films due to strong electron-phonon interaction was observed, the main parameters of the Urbach absorption edge were determined. Temperature dependences of the energy position of the exponential absorption edge and the Urbach energy are well described in the Einstein model. Dispersion and temperature dependences of refractive indices were analysed; a non-linear increase of the refractive indices with temperature was revealed. Disordering processes in the thin films were studied and compared with bulk composites, the differences between the thin films prepared by RTE and PLD were analysed.

Mirtazapine has a therapeutic potency in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced mice model of Parkinson’s disease

Science.gov (United States)

2014-01-01

Background Mirtazapine, a noradrenergic and specific serotonergic antidepressant (NaSSA), shows multiple pharmacological actions such as inhibiting presynaptic α2 noradrenaline receptor (NAR) and selectively activating 5-hydroxytriptamine (5-HT) 1A receptor (5-HT1AR). Mirtazapine was also reported to increase dopamine release in the cortical neurons with 5-HT dependent manner. To examine whether mirtazapine has a therapeutic potency in Parkinson’s disease (PD), we examined this compound in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated mice model of PD. Results Male C57BL/6 mice were subjected to MPTP treatment to establish a PD model. Mirtazapine was administered once a day for 3 days after MPTP treatment. MPTP-induced motor dysfunction, assessed by beam-walking and rota-rod tests, was significantly improved by administration of mirtazapine. Biochemical examinations by high performance liquid chromatography and western blot analysis suggested mirtazapine facilitated utilization of dopamine by increasing turnover and protein expression of transporters, without affecting on neurodegenerative process by MPTP. These therapeutic effects of mirtazapine were reduced by administration of WAY100635, an inhibitor for 5HT1AR, or of clonidine, a selective agonist for α2-NAR, or of prazosin, an inhibitor for α1-NAR, respectively. Conclusion Our results showed mirtazapine had a therapeutic potency against PD in a mouse model. Because PD patients sometimes show depression together, it will be a useful drug for a future PD treatment. PMID:24965042

Rational synthesis of high nuclearity Mo/Fe/S clusters: the reductive coupling approach in the convenient synthesis of (Cl(4)-cat)(2)Mo(2)Fe(6)S(8)(PR(3))(6) [R = Et, (n)Pr, (n)Bu] and the new [(Cl(4)-cat)(2)Mo(2)Fe(2)S(3)O(PEt(3))(3)Cl]-1/2(Fe(PEt(3))(2)(MeCN)(4)) and (Cl(4)-cat)(2)Mo(2)Fe(3)S(5)(PEt(3))(5) clusters.

Science.gov (United States)

Han, J; Koutmos, M; Ahmad, S A; Coucouvanis, D

2001-11-05

A general method for the synthesis of high nuclearity Mo/Fe/S clusters is presented and involves the reductive coupling of the (Et(4)N)(2)[(Cl(4)-cat)MoOFeS(2)Cl(2)] (I) and (Et(4)N)(2)[Fe(2)S(2)Cl(4)] (II) clusters. The reaction of I and II with Fe(PR(3))(2)Cl(2) or sodium salts of noncoordinating anions such as NaPF(6) or NaBPh(4) in the presence of PR(3) (R = Et, (n)Pr, or (n)Bu) affords (Cl(4)-cat)(2)Mo(2)Fe(6)S(8)(PR(3))(6) [R = Et (IIIa), (n)Pr (IIIb), (n)Bu (IIIc)], Fe(6)S(6)(PEt(3))(4)Cl(2) (IV) and (PF(6))[Fe(6)S(8)(P(n)Pr(3))(6)] (V) as byproducts. The isolation of (Et(4)N)[Fe(PEt(3))Cl(3)] (VI), NaCl, and SPEt(3) supports a reductive coupling mechanism. Cluster IV and V also have been synthesized by the reductive self-coupling of compound II. The reductive coupling reaction between I and II by PEt(3) and NaPF(6) in a 1:1 ratio produces the (Et(4)N)(2)[(Cl(4)-cat)Mo(L)Fe(3)S(4)Cl(3)] clusters [L = MeCN (VIIa), THF (VIIb)]. The hitherto unknown [(Cl(4)-cat)(2)Mo(2)Fe(2)S(3)O(PEt(3))(3)Cl](+) cluster (VIII) has been isolated as the 2:1 salt of the (Fe(PEt(3))(2)(MeCN)(4))(2+) cation after the reductive self-coupling reaction of I in the presence of Fe(PEt(3))(2)Cl(2). Cluster VIII crystallizes in the monoclinic space group P2(1)/c with a = 11.098(3) A, b = 22.827(6) A, c = 25.855(6) A, beta = 91.680(4) degrees, and Z = 4. The formal oxidation states of metal atoms in VIII have been assigned as Mo(III), Mo(IV), Fe(II), and Fe(III) on the basis of zero-field Mössbauer spectra. The Fe(PEt(3))(2)(MeCN)(4) cation of VIII is also synthesized independently, isolated as the BPh(4)(-) salt (IX), and has been structurally characterized. The reductive coupling of compound I also affords in low yield the new (Cl(4)-cat)(2)Mo(2)Fe(3)S(5)(PEt(3))(5) cluster (X) as a byproduct. Cluster X crystallizes in the monoclinic space group P2(1)/n with a = 14.811(3) A, b = 22.188(4) A, c = 21.864(4) A, beta = 100.124(3) degrees, and Z = 4 and the structure shows very short Mo

The 4p-5d, 6d and 4p-6s, 7s transitions of Mo IX

International Nuclear Information System (INIS)

Khatoon, S.; Chaghtai, M.S.Z.; Rahimullah, K.

1979-01-01

The transitions 4p-5d, 6d and 4p-6s, 7s have been studied for the first time in Mo IX. The authors have identified 42 4p-5d, 36 4p-6d, 22 4p-6s and 22 4p-7s transitions, establishing 16 4p 3 5d, 14 4p 3 6d and all the ten 4p 3 6s, 7s levels of the spectrum concerned. The ionization energy is estimated to be (1 323 700 +- 700)cm -1 or (164.11 +- 0.09)eV. The spectrum was recorded in sliding and open spark discharges with a 5 m grazing incidence spectrograph of Lund University (Sweden) from about 40 A to 440 A. (Auth.)

Fostering Distance Training Programme (DTP) Students' Access to Semester Examination Results via SMS at University of Rwanda-College of Education

Science.gov (United States)

Nizeyimana, Gerard; Yonah, Zaipuna O.; Nduwingoma, Mathias

2015-01-01

This paper presents a situation analysis and implementation of Distance Training Programme (DTP) Semester Examination Results Access (SERA) through Short Message Service (SMS) available anytime and anywhere. "Texting" or SMS mobile phone messaging is rapidly increasing communication in business and community service. The prompting…

Laenusaaja õiguste kaitse SMS-laenu lepingute puhul / Kalev Saare, Karin Sein, Mari Ann Simovart

Index Scriptorium Estoniae

Saare, Kalev, 1974-

2010-01-01

SMS-laenu lepingutele kohaldatavad normid, laenuandja teavitamiskohustus ja tarbija võimalused lepingust taganeda. Laenuandja intressi-, viivise- ja leppetrahvinõuded, intressikokkuleppe lubatavuse piirangud

Selected Contributions of the 6th European Meeting on Solar Chemistry and Photocatalysis: Environmental Applications (SPEA 6), 13th to 16th June 2010 Introduction

Czech Academy of Sciences Publication Activity Database

Klusoň, Petr; Krýsa, J.; Malato, S.; Oller, I.

2011-01-01

Roč. 161, č. 1 (2011), s. 2-2 ISSN 0920-5861 Grant - others:SMS(ES) CTQ2009-13459-C05-01 Institutional research plan: CEZ:AV0Z40720504 Keywords : solar light * environmental chemistry * photochemistry Subject RIV: CC - Organic Chemistry Impact factor: 3.407, year: 2011

Symmetric group: Algebraic formulas for some S/sub f/ 6j symbols and S/sub f/containsS/sub f/1 x S/sub f/2 3jm symbols

International Nuclear Information System (INIS)

Haase, R.W.; Dirl, R.

1986-01-01

Explicit rank-dependent expressions have been obtained for some symmetric group (S/sub f/) 6j symbols and some S/sub f/containsS/sub f/ 1 x S/sub f/ 2 3jm symbols using Butler's recursion method. A key point in deriving these results is the use of the reduced notation introduced by Murnaghan to label irreps. Various symmetries of the 6j and 3jm symbols have been imposed. These include the complex conjugation, permutation, and transpose conjugation. We incorporate a new symmetry that arises from the occurrence of the two isomorphic direct product groups S/sub f/ 1 x S/sub f/ 2 and S/sub f/ 2 x S/sub f/ 1 as subgroups of S/sub f/. In relation to the tables of 6j and 3jm symbols presented, a discussion is given of the symmetric group-unitary group duality

Optical frequency measurements of 6s 2S1/2-6p 2P3/2 transition in a 133Cs atomic beam using a femtosecond laser frequency comb

International Nuclear Information System (INIS)

Gerginov, V.; Tanner, C.E.; Diddams, S.; Bartels, A.; Hollberg, L.

2004-01-01

Optical frequencies of the hyperfine components of the D 2 line in 133 Cs are determined using high-resolution spectroscopy and a femtosecond laser frequency comb. A narrow-linewidth probe laser excites the 6s 2 S 1/2 (F=3,4)→6p 2 P 3/2 (F=2,3,4,5) transition in a highly collimated atomic beam. Fluorescence spectra are taken by scanning the laser frequency over the excited-state hyperfine structure. The laser optical frequency is referenced to a Cs fountain clock via a reference laser and a femtosecond laser frequency comb. A retroreflected laser beam is used to estimate and minimize the Doppler shift due to misalignment between the probe laser and the atomic beam. We achieve an angular resolution on the order of 5x10 -6 rad. The final uncertainties (∼±5 kHz) in the frequencies of the optical transitions are a factor of 20 better than previous results [T. Udem et al., Phys. Rev. A 62, 031801 (2000).]. We find the centroid of the 6s 2 S 1/2 →6p 2 P 3/2 transition to be f D2 =351 725 718.4744(51) MHz

Initial Radiometric Characteristics of KOMPSAT-3A Multispectral Imagery Using the 6S Radiative Transfer Model, Well-Known Radiometric Tarps, and MFRSR Measurements

Directory of Open Access Journals (Sweden)

Jong-Min Yeom

2017-02-01

Full Text Available On-orbit radiometric characterization of the multispectral (MS imagery of the Korea Aerospace Research Institute (KARI’s Korea Multi-Purpose Satellite-3A (KOMPSAT-3A, which was launched on 25 March 2015, was conducted to provide quantitative radiometric information about KOMPSAT-3A. During the in-orbit test (IOT, vicarious radiometric calibration of KOMPSAT-3A was performed using the Second Simulation of a Satellite Signal in the Solar Spectrum (6S radiative transfer model. The characteristics of radiometric tarps, the atmospheric optical depth from multi-filter rotating shadowband radiometer (MFRSR measurements, and sun–sensor–geometry were carefully considered, in order to calculate the exact top of atmosphere (TOA radiance received by KOMPSAT-3A MS bands. In addition, the bidirectional reflectance distribution function (BRDF behaviors of the radiometric tarps were measured in the laboratory with a two-dimensional hyperspectral gonioradiometer, to compensate for the geometry discrepancy between the satellite and the ASD FieldSpec® 3 spectroradiometer. The match-up datasets between the TOA radiance and the digital number (DN from KOMPSAT-3A were used to determine DN-to-radiance conversion factors, based on linear least squares fitting for two field campaigns. The final results showed that the R2 values between the observed and simulated radiances for the blue, green, red, and near-infrared (NIR bands, are greater than 0.998. An approximate error budget analysis for the vicarious calibration of KOMPSAT-3A showed an error of less than 6.8%. When applying the laboratory-based BRDF correction to the case of higher viewing zenith angle geometry, the gain ratio was improved, particularly for the blue (1.3% and green (1.2% bands, which exhibit high sensitivity to the BRDF of radiometric tarps during the backward-scattering phase. The calculated gain ratio between the first and second campaigns showed a less than 5% discrepancy, indicating that

(1S-1,2-O-Benzylidene-α-d-glucurono-6,3-lactone

Directory of Open Access Journals (Sweden)

David J. Watkin

2009-02-01

Full Text Available X-ray crystallographic analysis has established that the major product from the protection of d-glucoronolactone with benzaldehyde is (1S-1,2-O-benzylidene-α-d-glucurono-6,3-lactone, C13H12O6, rather than the R epimer. The crystal structure exists as O—H...O hydrogen-bonded chains of molecules lying parallel to the a axis. The absolute configuration was determined by the use of d-glucuronolactone as the starting material.

Permutation-symmetric three-particle hyper-spherical harmonics based on the S3⊗SO(3rot⊂O(2⊗SO(3rot⊂U(3⋊S2⊂O(6 subgroup chain

Directory of Open Access Journals (Sweden)

Igor Salom

2017-07-01

Full Text Available We construct the three-body permutation symmetric hyperspherical harmonics to be used in the non-relativistic three-body Schrödinger equation in three spatial dimensions (3D. We label the state vectors according to the S3⊗SO(3rot⊂O(2⊗SO(3rot⊂U(3⋊S2⊂O(6 subgroup chain, where S3 is the three-body permutation group and S2 is its two element subgroup containing transposition of first two particles, O(2 is the “democracy transformation”, or “kinematic rotation” group for three particles; SO(3rot is the 3D rotation group, and U(3,O(6 are the usual Lie groups. We discuss the good quantum numbers implied by the above chain of algebras, as well as their relation to the S3 permutation properties of the harmonics, particularly in view of the SO(3rot⊂SU(3 degeneracy. We provide a definite, practically implementable algorithm for the calculation of harmonics with arbitrary finite integer values of the hyper angular momentum K, and show an explicit example of this construction in a specific case with degeneracy, as well as tables of K≤6 harmonics. All harmonics are expressed as homogeneous polynomials in the Jacobi vectors (λ,ρ with coefficients given as algebraic numbers unless the “operator method” is chosen for the lifting of the SO(3rot⊂SU(3 multiplicity and the dimension of the degenerate subspace is greater than four – in which case one must resort to numerical diagonalization; the latter condition is not met by any K≤15 harmonic, or by any L≤7 harmonic with arbitrary K. We also calculate a certain type of matrix elements (the Gaunt integrals of products of three harmonics in two ways: 1 by explicit evaluation of integrals and 2 by reduction to known SU(3 Clebsch–Gordan coefficients. In this way we complete the calculation of the ingredients sufficient for the solution to the quantum-mechanical three-body bound state problem.

Active SMS-based influenza vaccine safety surveillance in Australian children.

Science.gov (United States)

Pillsbury, Alexis; Quinn, Helen; Cashman, Patrick; Leeb, Alan; Macartney, Kristine

2017-12-18

Australia's novel, active surveillance system, AusVaxSafety, monitors the post-market safety of vaccines in near real time. We analysed cumulative surveillance data for children aged 6 months to 4 years who received seasonal influenza vaccine in 2015 and/or 2016 to determine: adverse event following immunisation (AEFI) rates by vaccine brand, age and concomitant vaccine administration. Parent/carer reports of AEFI occurring within 3 days of their child receiving an influenza vaccine in sentinel immunisation clinics were solicited by Short Message Service (SMS) and/or email-based survey. Retrospective data from 2 years were combined to examine specific AEFI rates, particularly fever and medical attendance as a proxy for serious adverse events (SAE), with and without concomitant vaccine administration. As trivalent influenza vaccines (TIV) were funded in Australia's National Immunisation Program (NIP) in 2015 and quadrivalent (QIV) in 2016, respectively, we compared their safety profiles. 7402 children were included. Data were reported weekly through each vaccination season; no safety signals or excess of adverse events were detected. More children who received a concomitant vaccine had fever (7.5% versus 2.8%; p vaccine was associated with the highest increase in AEFI rates among children receiving a specified concomitant vaccine: 30.3% reported an AEFI compared with 7.3% who received an influenza vaccine alone (p safety profiles included low and expected AEFI rates (fever: 4.3% for TIV compared with 3.2% for QIV (p = .015); injection site reaction: 1.9% for TIV compared with 3.0% for QIV (p safety profile between brands. Active participant-reported data provided timely vaccine brand-specific safety information. Our surveillance system has particular utility in monitoring the safety of influenza vaccines, given that they may vary in composition annually. Copyright © 2017 Elsevier Ltd. All rights reserved.

Implementation vigenere algorithm using microcontroller for sending SMS in monitoring radioactive substances transport system

International Nuclear Information System (INIS)

Adi Abimanyu; Nurhidayat; Jumari

2013-01-01

Aspects of safety and security of radioactive substances from the sender to the receiver is to be secured for not to harm humans. In general, monitoring the transport of radioactive materials is done by communication with a telephone conversation to determine the location and rate of exposure radioactive substances. From the aspect of safety, communication through telephone conversations easily interpreted by others, in addition the possibility of human-error is quite high. SMS service is known for its ease in terms of use so that SMS can be used as a substitute for communication through telephone conversations to monitor the rate of radiation exposure and the position of radioactive substances in the transport of radioactive substances. The system monitors the transport of radioactive materials developed by implement vigenere algorithms using a microcontroller for sending SMS (Short Message Service) to communicate. Tests was conducted to testing encryption and description and computation time required. From the test results obtained they have been successfully implemented vigenere algorithm to encrypt and decrypt the messages on the transport of radioactive monitoring system and the computational time required to encrypt and decrypt the data is 13.05 ms for 36 characters and 13.61 for 37 characters. So for every single character require computing time 0.56 ms. (author)

Studying the Specific Activity of the Amide Form of HLDF-6 Peptide using the Transgenic Model of Alzheimer’s Disease

Science.gov (United States)

Bogachouk, A. P.; Storozheva, Z. I.; Telegin, G. B.; Chernov, A. S.; Proshin, A. T.; Sherstnev, V. V.; Zolotarev, Yu. A.; Lipkin, V. M.

2017-01-01

The neuroprotective and nootropic activities of the amide form (AF) of the HLDF-6 peptide (TGENHR-NH2) were studied in transgenic mice of the B6C3-Tg(APPswe,PSEN1de9)85Dbo (Tg+) line (the animal model of familial Alzheimer’s disease (AD)). The study was performed in 4 mouse groups: group 1 (study group): Tg+ mice intranasally injected with the peptide at a dose of 250 μg/kg; group 2 (active control): Tg+ mice intranasally injected with normal saline; group 3 (control 1): Tg- mice; and group 4 (control 2): C57Bl/6 mice. The cognitive functions were evaluated using three tests: the novel object recognition test, the conditioned passive avoidance task, and the Morris water maze. The results testify to the fact that the pharmaceutical substance (PhS) based on the AF of HLDF-6 peptide at a dose of 250 μg/kg administered intranasally efficiently restores the disturbed cognitive functions in transgenic mice. These results are fully consistent with the data obtained in animal models of Alzheimer’s disease induced by the injection of the beta-amyloid (βA) fragment 25-35 into the giant-cell nucleus basalis of Meynert or by co-injection of the βA fragment 25-35 and ibotenic acid into the hippocampus, and the model of ischemia stroke (chronic bilateral occlusion of carotids, 2VO). According to the overall results, PhS based on AF HLDF-6 was chosen as an object for further investigation; the dose of 250 μg/kg was used as an effective therapeutic dose. Intranasal administration was the route for delivery. PMID:29104777

Impact of Short Interval SMS Digital Data on Wind Vector Determination for a Severe Local Storms Area

Science.gov (United States)

Peslen, C. A.

1979-01-01

The impact of 5 minute interval SMS-2 visible digital image data in analyzing severe local storms is examined using wind vectors derived from cloud tracking on time lapsed sequence of geosynchronous satellite images. The cloud tracking areas are located in the Central Plains, where on 6 May 1975, hail-producing thunderstorms occurred ahead of a well defined dry line. The results demonstrate that satellite-derived wind vectors and their associated divergence fields complement conventional meteorological analyses in describing the conditions preceding severe local storm development.

STS-26 MS Nelson on fixed based (FB) shuttle mission simulator (SMS) middeck

Science.gov (United States)

1988-01-01

STS-26 Discovery, Orbiter Vehicle (OV) 103, Mission Specialist (MS) George D. Nelson trains on the middeck of the fixed based (FB) shuttle mission simulator (SMS). Nelson, wearing communications assembly headset, adjusts camera mounting bracket.

Association between PI3K/Akt/mTOR/p70S6K signaling pathway and hepatic fibrosis

Directory of Open Access Journals (Sweden)

WU Changhui

2015-11-01

Full Text Available Phosphoinositide 3-kinase (PI3K/protein kinase-B (AkT/mammalian target of rapamycin (mTOR/70-kDa ribosomal protein S6 kinase (p70S6K, PI3K/Akt/mTOR/p70S6K, is an important signaling pathway in the life activities of cells, and it plays an important role in promoting the growth, proliferation, invasion, and anti-apoptosis of cells and promoting angiogenesis. It was clarified that the PI3K/Akt/mTOR/p70S6K signaling pathway is involved in regulating the activities of hepatic stellate cell(HSC, thus influencing the development and progression of hepatic fibrosis. Analysis demonstrated that blocking any target of the PI3K/Akt/mTOR/p70S6K signaling pathway can inhibit the activation and proliferation of HSC, promote the apoptosis of HSC, inhibit the extracellular matrix secretion from HSC, and delay the progression of hepatic fibrosis. Blocking the pathway is expected to be a treatment strategy for hepatic fibrosis.

Structural and optical properties of annealed and illuminated (Ag3AsS3)0.6(As2S3)0.4 thin films

Science.gov (United States)

Studenyak, I. P.; Neimet, Yu. Yu.; Rati, Y. Y.; Stanko, D.; Kranjčec, M.; Kökényesi, S.; Daróci, L.; Bohdan, R.

2014-11-01

(Ag3AsS3)0.6(As2S3)0.4 thin films were deposited upon a quartz substrate by rapid thermal evaporation. Structural studies of the as-deposited, annealed and illuminated films were performed using XRD, scanning electron and atomic force microscopies. Surfaces of all the films were found to be covered with Ag-rich crystalline micrometer sized cones. Thermal annealing leads to mechanical deformation of part of the cones and their detachment from the base film surface while the laser illumination leads to the new formations appearance on the surface of thin films. The spectroscopic studies of optical transmission spectra for as-deposited, annealed and illuminated thin films were carried out. The optical absorption spectra in the region of its exponential behaviour were analysed, the dispersion dependences of refractive index as well as their variation after annealing and illumination were investigated.

Fe-solubility of Ni7S6 and Ni9S8: Thermodynamic analysis

International Nuclear Information System (INIS)

Waldner, P.

2011-01-01

Experimental data on phase equilibria have been used for thermodynamic analysis of the iron solubility of the nickel sulfides Ni 7 S 6 and Ni 9 S 8 . For both compounds, a two-sublattice approach within the framework of the compound energy formalism has been applied to perform Gibbs free energy modelling at 0.1 MPa total pressure consistently embedded in recent thermodynamic assessment studies of other iron-nickel-sulfides. The predicted maxima of iron solubility around 3 at% of Ni 7 S 6 and 5.5 at% of Ni 9 S 8 are confirmed by experimental data. The calculations of complex ternary phase relations with Fe-bearing Ni 7 S 6 and Ni 9 S 8 gain further improvement. The first internally consistent description of all thermodynamically stable phases known in the literature for the iron-nickel-sulfur system is completed.

Views of STS-5 crew during a training session in the SMS

Science.gov (United States)

1982-01-01

Views of STS-5 crew during a training session in the Shuttle Mission Simulator (SMS). Astronaut Robert F. Overmyer, STS-5 pilot, participates in training session wearing a communications kit assembly (ASSY). He is dressed in regular flight suit and is studying flight documentation.

Hyper-Resolution Groundwater Modeling using MODFLOW 6

Science.gov (United States)

Hughes, J. D.; Langevin, C.

2017-12-01

MODFLOW 6 is the latest version of the U.S. Geological Survey's modular hydrologic model. MODFLOW 6 was developed to synthesize many of the recent versions of MODFLOW into a single program, improve the way different process models are coupled, and to provide an object-oriented framework for adding new types of models and packages. The object-oriented framework and underlying numerical solver make it possible to tightly couple any number of hyper-resolution models within coarser regional models. The hyper-resolution models can be used to evaluate local-scale groundwater issues that may be affected by regional-scale forcings. In MODFLOW 6, hyper-resolution meshes can be maintained as separate model datasets, similar to MODFLOW-LGR, which simplifies the development of a coarse regional model with imbedded hyper-resolution models from a coarse regional model. For example, the South Atlantic Coastal Plain regional water availability model was converted from a MODFLOW-2000 model to a MODFLOW 6 model. The horizontal discretization of the original model is approximately 3,218 m x 3,218 m. Hyper-resolution models of the Aiken and Sumter County water budget areas in South Carolina with a horizontal discretization of approximately 322 m x 322 m were developed and were tightly coupled to a modified version of the original coarse regional model that excluded these areas. Hydraulic property and aquifer geometry data from the coarse model were mapped to the hyper-resolution models. The discretization of the hyper-resolution models is fine enough to make detailed analyses of the effect that changes in groundwater withdrawals in the production aquifers have on the water table and surface-water/groundwater interactions. The approach used in this analysis could be applied to other regional water availability models that have been developed by the U.S. Geological Survey to evaluate local scale groundwater issues.

Modeling ion exchange in clinoptilolite using the EQ3/6 geochemical modeling code

International Nuclear Information System (INIS)

Viani, B.E.; Bruton, C.J.

1992-06-01

Assessing the suitability of Yucca Mtn., NV as a potential repository for high-level nuclear waste requires the means to simulate ion-exchange behavior of zeolites. Vanselow and Gapon convention cation-exchange models have been added to geochemical modeling codes EQ3NR/EQ6, allowing exchange to be modeled for up to three exchangers or a single exchanger with three independent sites. Solid-solution models that are numerically equivalent to the ion-exchange models were derived and also implemented in the code. The Gapon model is inconsistent with experimental adsorption isotherms of trace components in clinoptilolite. A one-site Vanselow model can describe adsorption of Cs or Sr on clinoptilolite, but a two-site Vanselow exchange model is necessary to describe K contents of natural clinoptilolites

A 3D human neural cell culture system for modeling Alzheimer’s disease

Science.gov (United States)

Kim, Young Hye; Choi, Se Hoon; D’Avanzo, Carla; Hebisch, Matthias; Sliwinski, Christopher; Bylykbashi, Enjana; Washicosky, Kevin J.; Klee, Justin B.; Brüstle, Oliver; Tanzi, Rudolph E.; Kim, Doo Yeon

2015-01-01

Stem cell technologies have facilitated the development of human cellular disease models that can be used to study pathogenesis and test therapeutic candidates. These models hold promise for complex neurological diseases such as Alzheimer’s disease (AD) because existing animal models have been unable to fully recapitulate all aspects of pathology. We recently reported the characterization of a novel three-dimensional (3D) culture system that exhibits key events in AD pathogenesis, including extracellular aggregation of β-amyloid and accumulation of hyperphosphorylated tau. Here we provide instructions for the generation and analysis of 3D human neural cell cultures, including the production of genetically modified human neural progenitor cells (hNPCs) with familial AD mutations, the differentiation of the hNPCs in a 3D matrix, and the analysis of AD pathogenesis. The 3D culture generation takes 1–2 days. The aggregation of β-amyloid is observed after 6-weeks of differentiation followed by robust tau pathology after 10–14 weeks. PMID:26068894

Early cardiopulmonary resuscitation and use of Automated External Defibrillators by laypersons in out-of-hospital cardiac arrest using an SMS alert service

NARCIS (Netherlands)

Scholten, Annemieke C.; van Manen, Jeanette Gabrielle; van der Worp, Wim E.; IJzerman, Maarten Joost; Doggen, Catharina Jacoba Maria

2011-01-01

Aim: To evaluate an SMS service (SMS = short message service = text message) with which laypersons are alerted to go to patients with suspected out-of-hospital cardiac arrest and perform early cardiopulmonary resuscitation (CPR) and use an Automated External Defibrillator (AED). This study is the

IR, FT-ICR-MS studies on (1'S, 6'S)-1-cyclopropyl-7-(2,8-diazabicyclo[4.3.0] non-8-yl)-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride salt.

Science.gov (United States)

Lin, Zhiwei

2014-01-01

The infrared spectra of (1'S, 6'S)-1-cyclopropyl-7-(2,8-diazabicyclo[4.3.0] non-8-yl)-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride salt (CLF-HCl) were studied and compared with free base. Their fragmentation pathways were investigated using tandem mass spectrometric (MS/MS) techniques on Fourier-transform ion cyclotron resonance spectrum, and many characteristic fragment ions were found. Copyright © 2013 Elsevier B.V. All rights reserved.

The chemistry–climate model ECHAM6.3-HAM2.3-MOZ1.0

Directory of Open Access Journals (Sweden)

M. G. Schultz

2018-05-01

Full Text Available The chemistry–climate model ECHAM-HAMMOZ contains a detailed representation of tropospheric and stratospheric reactive chemistry and state-of-the-art parameterizations of aerosols using either a modal scheme (M7 or a bin scheme (SALSA. This article describes and evaluates the model version ECHAM6.3-HAM2.3-MOZ1.0 with a focus on the tropospheric gas-phase chemistry. A 10-year model simulation was performed to test the stability of the model and provide data for its evaluation. The comparison to observations concentrates on the year 2008 and includes total column observations of ozone and CO from IASI and OMI, Aura MLS observations of temperature, HNO3, ClO, and O3 for the evaluation of polar stratospheric processes, an ozonesonde climatology, surface ozone observations from the TOAR database, and surface CO data from the Global Atmosphere Watch network. Global budgets of ozone, OH, NOx, aerosols, clouds, and radiation are analyzed and compared to the literature. ECHAM-HAMMOZ performs well in many aspects. However, in the base simulation, lightning NOx emissions are very low, and the impact of the heterogeneous reaction of HNO3 on dust and sea salt aerosol is too strong. Sensitivity simulations with increased lightning NOx or modified heterogeneous chemistry deteriorate the comparison with observations and yield excessively large ozone budget terms and too much OH. We hypothesize that this is an impact of potential issues with tropical convection in the ECHAM model.

The chemistry-climate model ECHAM6.3-HAM2.3-MOZ1.0

Science.gov (United States)

Schultz, Martin G.; Stadtler, Scarlet; Schröder, Sabine; Taraborrelli, Domenico; Franco, Bruno; Krefting, Jonathan; Henrot, Alexandra; Ferrachat, Sylvaine; Lohmann, Ulrike; Neubauer, David; Siegenthaler-Le Drian, Colombe; Wahl, Sebastian; Kokkola, Harri; Kühn, Thomas; Rast, Sebastian; Schmidt, Hauke; Stier, Philip; Kinnison, Doug; Tyndall, Geoffrey S.; Orlando, John J.; Wespes, Catherine

2018-05-01

The chemistry-climate model ECHAM-HAMMOZ contains a detailed representation of tropospheric and stratospheric reactive chemistry and state-of-the-art parameterizations of aerosols using either a modal scheme (M7) or a bin scheme (SALSA). This article describes and evaluates the model version ECHAM6.3-HAM2.3-MOZ1.0 with a focus on the tropospheric gas-phase chemistry. A 10-year model simulation was performed to test the stability of the model and provide data for its evaluation. The comparison to observations concentrates on the year 2008 and includes total column observations of ozone and CO from IASI and OMI, Aura MLS observations of temperature, HNO3, ClO, and O3 for the evaluation of polar stratospheric processes, an ozonesonde climatology, surface ozone observations from the TOAR database, and surface CO data from the Global Atmosphere Watch network. Global budgets of ozone, OH, NOx, aerosols, clouds, and radiation are analyzed and compared to the literature. ECHAM-HAMMOZ performs well in many aspects. However, in the base simulation, lightning NOx emissions are very low, and the impact of the heterogeneous reaction of HNO3 on dust and sea salt aerosol is too strong. Sensitivity simulations with increased lightning NOx or modified heterogeneous chemistry deteriorate the comparison with observations and yield excessively large ozone budget terms and too much OH. We hypothesize that this is an impact of potential issues with tropical convection in the ECHAM model.

Overexpression of Notch3 and pS6 Is Associated with Poor Prognosis in Human Ovarian Epithelial Cancer

Directory of Open Access Journals (Sweden)

Zhaoxia Liu

2016-01-01

Full Text Available Notch3 and pS6 play important roles in tumor angiogenesis. To assess the expression of Notch3 and pS6 in Chinese ovarian epithelial cancer patients, a ten-year follow-up study was performed in ovarian epithelial cancer tissues from 120 specimens of human ovarian epithelial cancer, 30 specimens from benign ovarian tumors, and 30 samples from healthy ovaries by immunohistochemistry. The results indicate that the expression of Notch3 and pS6 was higher in ovarian epithelial cancer than in normal ovary tissues and in benign ovarian tumor tissues (p0.05 but positively associated with clinical stage, pathological grading, histologic type, lymph node metastasis, and ascites (p<0.05 or p<0.01. A follow-up survey of 64 patients with ovarian epithelial cancer showed that patients with high Notch3 and pS6 expression had a shorter survival time (p<0.01, in which the clinical stage (p<0.05 and Notch3 expression (p<0.01 played important roles. In conclusion, Notch3 and pS6 are significantly related to ovarian epithelial cancer development and prognosis, and their combination represents a potential biomarker and therapeutic target in ovarian tumor angiogenesis.

Ultra-compact SWIR telephoto lens design with SMS method

OpenAIRE

Wang, Lin; Benitez Gimenez, Pablo; Miñano Dominguez, Juan Carlos; Infante Herrero, Jose Manuel; Fuente, Marta de la; Biot Marí, Guillermo

2011-01-01

In this work, we propose two new optical structures, using the Simultaneous Multiple Surfaces (SMS) method, comprised of 2 reflecting surfaces and 2 refracting surfaces, 800mm focal length, f/8 (aperture diameter 100 mm) and 1.18 0 diagonal field of view in the SWIR band. The lens surfaces are rotational symmetric and calculated to have good control of non-paraxial rays. We have achieved designs with excellent performance, and with total system length of less than 60 mm.

Injury risk in Danish youth and senior elite handball using a new SMS text messages approach.

Science.gov (United States)

Moller, Merete; Attermann, Jorn; Myklebust, Grethe; Wedderkopp, Niels

2012-06-01

To assess the injury incidence in elite handball, and if gender and previous injuries are risk factors for new injuries. Cohort study of 517 male and female elite handball players (age groups under (u)16, u-18 and senior). Participants completed a web survey establishing injury history, demographic information and sports experience, and provided weekly reports of time-loss injuries and handball exposure for 31 weeks by short message service text messaging (SMS). Injuries were further classified by telephone interview. The weekly response rate ranged from 85% to 90% illustrating the promise of the SMS system as a tool in injury surveillance. Of 448 reported injuries, 165 injuries (37%) were overuse injuries and 283 (63%) traumatic injuries. Knee (19%) and ankle (29%) were the most common traumatic injuries. The injury incidence during match play was 23.5 (95% CI 17.8 to 30.4), 15.1 (95% CI 9.7 to 22.2), 11.1 (95% CI 7.0 to 16.6) injuries per 1000 match hours among senior, u-18 and u-16 players, respectively. U-18 male players had an overall 1.76 (95% CI 1.10 to 2.80) times higher risk of injury compared to females. Having had two or more previous injuries causing absence from handball for more than 4 weeks increased the risk of new injury in the u-16 group (IRR: 1.79 (95% CI 1.03 to 3.11)-2.23 (95% CI 1.22 to 4.10)). The incidence of time-loss injuries in elite handball was higher during match play than previously reported in recreational handball. Previous injuries were a risk factor for new injuries among u-16 players. Male players had a significant higher injury rate in the u-18 group.

High-pressure anisotropic distortion of Pb3Bi2S6

DEFF Research Database (Denmark)

Olsen, Lars Arnskov; Balic Zunic, Tonci; Makovicky, Emil

2008-01-01

The compound Pb3Bi2S6 is investigated by X-ray diffraction on single crystals in a diamond-anvil cell between 0.0001 and 10.5 GPa. It undergoes a first-order phase transition at hydrostatic pressure between 3.7 and 4.9 Gpa. The space group symmetry changes from Bbmm to Pbnm, and the unit......-cell volume decreases by 4%. The transition is strongly anisotropic, with a contraction along one of the crystal axes by 16% and expansion along another one by 14%. This is a piezoplastic phase transition, a displacive pressure-induced phase transition with systematic shearing of atomic planes and a migration...

Tris(dibenzoylmethanido-κ2O,O′[(6S,8S-(+-7,7-dimethyl-3-(2-pyridyl-5,6,7,8-tetrahydro-6,8-methanoisoquinoline-κ2N,N′]gadolinium(III

Directory of Open Access Journals (Sweden)

Xi-Li Li

2009-09-01

Full Text Available In the title compound, [Gd(C15H11O23(C17H18N2], the GdIII atom is coordinated by six O atoms from three β-diketonate ligands and two N atoms from a chiral ligand LS,S-(+-7,7-dimethyl-3-(2-pyridyl-5,6,7,8-tetrahydro-6,8-methanoisoquinoline, in a coordination geometry best described as distorted square-antiprismatic.

Lrit3 deficient mouse (nob6): a novel model of complete congenital stationary night blindness (cCSNB).

Science.gov (United States)

Neuillé, Marion; El Shamieh, Said; Orhan, Elise; Michiels, Christelle; Antonio, Aline; Lancelot, Marie-Elise; Condroyer, Christel; Bujakowska, Kinga; Poch, Olivier; Sahel, José-Alain; Audo, Isabelle; Zeitz, Christina

2014-01-01

Mutations in LRIT3, coding for a Leucine-Rich Repeat, immunoglobulin-like and transmembrane domains 3 protein lead to autosomal recessive complete congenital stationary night blindness (cCSNB). The role of the corresponding protein in the ON-bipolar cell signaling cascade remains to be elucidated. Here we genetically and functionally characterize a commercially available Lrit3 knock-out mouse, a model to study the function and the pathogenic mechanism of LRIT3. We confirm that the insertion of a Bgeo/Puro cassette in the knock-out allele introduces a premature stop codon, which presumably codes for a non-functional protein. The mouse line does not harbor other mutations present in common laboratory mouse strains or in other known cCSNB genes. Lrit3 mutant mice exhibit a so-called no b-wave (nob) phenotype with lacking or severely reduced b-wave amplitudes in the scotopic and photopic electroretinogram (ERG), respectively. Optomotor tests reveal strongly decreased optomotor responses in scotopic conditions. No obvious fundus auto-fluorescence or histological retinal structure abnormalities are observed. However, spectral domain optical coherence tomography (SD-OCT) reveals thinned inner nuclear layer and part of the retina containing inner plexiform layer, ganglion cell layer and nerve fiber layer in these mice. To our knowledge, this is the first time that SD-OCT technology is used to characterize an animal model for CSNB. This phenotype is noted at 6 weeks and at 6 months. The stationary nob phenotype of mice lacking Lrit3, which we named nob6, confirms the findings previously reported in patients carrying LRIT3 mutations and is similar to other cCSNB mouse models. This novel mouse model will be useful for investigating the pathogenic mechanism(s) associated with LRIT3 mutations and clarifying the role of LRIT3 in the ON-bipolar cell signaling cascade.

Lrit3 deficient mouse (nob6: a novel model of complete congenital stationary night blindness (cCSNB.

Directory of Open Access Journals (Sweden)

Marion Neuillé

Full Text Available Mutations in LRIT3, coding for a Leucine-Rich Repeat, immunoglobulin-like and transmembrane domains 3 protein lead to autosomal recessive complete congenital stationary night blindness (cCSNB. The role of the corresponding protein in the ON-bipolar cell signaling cascade remains to be elucidated. Here we genetically and functionally characterize a commercially available Lrit3 knock-out mouse, a model to study the function and the pathogenic mechanism of LRIT3. We confirm that the insertion of a Bgeo/Puro cassette in the knock-out allele introduces a premature stop codon, which presumably codes for a non-functional protein. The mouse line does not harbor other mutations present in common laboratory mouse strains or in other known cCSNB genes. Lrit3 mutant mice exhibit a so-called no b-wave (nob phenotype with lacking or severely reduced b-wave amplitudes in the scotopic and photopic electroretinogram (ERG, respectively. Optomotor tests reveal strongly decreased optomotor responses in scotopic conditions. No obvious fundus auto-fluorescence or histological retinal structure abnormalities are observed. However, spectral domain optical coherence tomography (SD-OCT reveals thinned inner nuclear layer and part of the retina containing inner plexiform layer, ganglion cell layer and nerve fiber layer in these mice. To our knowledge, this is the first time that SD-OCT technology is used to characterize an animal model for CSNB. This phenotype is noted at 6 weeks and at 6 months. The stationary nob phenotype of mice lacking Lrit3, which we named nob6, confirms the findings previously reported in patients carrying LRIT3 mutations and is similar to other cCSNB mouse models. This novel mouse model will be useful for investigating the pathogenic mechanism(s associated with LRIT3 mutations and clarifying the role of LRIT3 in the ON-bipolar cell signaling cascade.

Mobile Learning via SMS at Open University Malaysia: Equitable, Effective, and Sustainable

Science.gov (United States)

Lim, Tina; Fadzil, Mansor; Mansor, Norziati

2011-01-01

This article describes Open University Malaysia's efforts at enhancing the blended learning approach for undergraduate distance learners with the successful implementation of the Mobile Learning via SMS initiative. The pilot project was implemented in the May 2009 semester, and this coming January 2011 semester will be in its sixth consecutive…

STS-37 Mission Specialist (MS) Godwin during simulation in JSC's FB-SMS

Science.gov (United States)

1991-01-01

STS-37 Mission Specialist (MS) Linda M. Godwin rehearses some phases of her scheduled duties on the middeck of the fixed-based (FB) shuttle mission simulator (SMS) located in JSC's Mission Simulation and Training Facility Bldg 5. Godwin is inspecting supplies stowed in the middeck lockers during this unsuited simulation.

A CCTV system with SMS alert (CMDSA): An implementation of pixel processing algorithm for motion detection

Science.gov (United States)

Rahman, Nurul Hidayah Ab; Abdullah, Nurul Azma; Hamid, Isredza Rahmi A.; Wen, Chuah Chai; Jelani, Mohamad Shafiqur Rahman Mohd

2017-10-01

Closed-Circuit TV (CCTV) system is one of the technologies in surveillance field to solve the problem of detection and monitoring by providing extra features such as email alert or motion detection. However, detecting and alerting the admin on CCTV system may complicate due to the complexity to integrate the main program with an external Application Programming Interface (API). In this study, pixel processing algorithm is applied due to its efficiency and SMS alert is added as an alternative solution for users who opted out email alert system or have no Internet connection. A CCTV system with SMS alert (CMDSA) was developed using evolutionary prototyping methodology. The system interface was implemented using Microsoft Visual Studio while the backend components, which are database and coding, were implemented on SQLite database and C# programming language, respectively. The main modules of CMDSA are motion detection, capturing and saving video, image processing and Short Message Service (SMS) alert functions. Subsequently, the system is able to reduce the processing time making the detection process become faster, reduce the space and memory used to run the program and alerting the system admin instantly.

SMS messages increase adherence to rapid diagnostic test results among malaria patients: results from a pilot study in Nigeria.

Science.gov (United States)

Modrek, Sepideh; Schatzkin, Eric; De La Cruz, Anna; Isiguzo, Chinwoke; Nwokolo, Ernest; Anyanti, Jennifer; Ujuju, Chinazo; Montagu, Dominic; Liu, Jenny

2014-02-25

The World Health Organization now recommends parasitological confirmation for malaria case management. Rapid diagnostic tests (RDTs) for malaria are an accurate and simple diagnostic to confirm parasite presence in blood. However, where they have been deployed, adherence to RDT results has been poor, especially when the test result is negative. Few studies have examined adherence to RDTs distributed or purchased through the private sector. The Rapid Examination of Malaria and Evaluation of Diagnostic Information (REMEDI) study assessed the acceptability of and adherence to RDT results for patients seeking care from private sector drug retailers in two cities in Oyo State in south-west Nigeria. In total, 465 adult participants were enrolled upon exit from a participating drug shop having purchased anti-malaria drugs for themselves. Participants were given a free RDT and the appropriate treatment advice based on their RDT result. Short Message Service (SMS) text messages reiterating the treatment advice were sent to a randomly selected half of the participants one day after being tested. Participants were contacted via phone four days after the RDT was conducted to assess adherence to the RDT information and treatment advice. Adherence to RDT results was 14.3 percentage points (P-val <0.001) higher in the treatment group who were sent the SMS. The higher adherence in the treatment group was robust to several specification tests and the estimated difference in adherence ranged from 9.7 to 16.1 percentage points. Further, the higher adherence to the treatment advice was specific to the treatment advice for anti-malarial drugs and not other drugs purchased to treat malaria symptoms in the RDT-negative participants who bought both anti-malarial and symptom drugs. There was no difference in adherence for the RDT-positive participants who were sent the SMS. SMS text messages substantially increased adherence to RDT results for patients seeking care for malaria from

LANGUE(S ÉPHÉMÈRE(S : PARLERS JEUNES, SMS ET VERLAN, UN TOURBILLON LINGUISTIQUE RÉINVENTANT LE LANGAGE STANDARD ET LA NORME ? / EPHEMERAL LANGUAGE(S: YOUNG DIALECTS, SMS AND VERLAN. A LINGUISTIC WHIRLPOOL REINVENTING STANDARD LANGUAGE AND NORM? / LIMBA/LIMBILE EFEMERE: DIALECTELE NOI, SMS ŞI VERLAN, UN VÂRTEJ LINGVISTIC CARE REINVENTEAZĂ LIMBAJUL STANDARD ŞI NORMA?

Directory of Open Access Journals (Sweden)

Loredana Trovato

2013-11-01

Full Text Available Cet article veut réfléchir sur l’idée d’éphémère en tant « qu’apanage de notre modernité » dans les formes de communication actuelles, telles que les parlers jeunes, le SMS et le verlan (en particulier, le verlan utilisé dans les chansons rap et slam. Si Thierry Bulot met en évidence le fait que la langue – en tant que norme – n’évolue plus, elle continue cependant de changer, de se métamorphoser en un organisme ductile, versatile et façonnable selon les exigences de la société contemporaine. Car, comme l’indiquait Vivienne Méla il y a vingt ans désormais, ces langues sont le véritable « miroir » des individus qui les parlent, les vivent, les « habitent ». Et pourtant, elles sont éphémères parce qu’elles refusent la norme, mais aussi parce que la norme les refuse. Nos exemples chercheront à illustrer tous les niveaux de description linguistique, afin de montrer que ces langues sont comme une sorte de tourbillon linguistique bouleversant le français standard et même si elles restent dans le domaine de l’éphémère, elles ne perdent pas leur valeur et leur importance pour le développement dynamique des sociétés. Il s’ensuit qu’il est possible d’attribuer une connotation positive à l’éphémère comme une nouvelle dimension linguistique dans les mouvements évolutifs de la société complexe.

Role of interleukin-6 and pentraxin 3 as an early marker in Peyronie’s disease

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Arda Atar

2017-04-01

Full Text Available Inflammation is mechanistically involved in the development of Peyronie’s disease (PD. The aim of this study is to assess the relevance of serum pentraxin 3 (PTX3 and interleukin-6 (IL-6 concentrations in PD. The study enrolled 40 patients with PD in the acute phase and 40 healthy controls. Plasma PTX3 and IL-6 concentrations were evaluated in 40 patients in the acute phase of PD and 40 healthy controls by enzyme-linked immunosorbent assay. Serum concentrations of both PTX3 and IL-6 were significantly higher in the PD patients than in the control group (p=0.001 and p=0.001, respectively. There was a significant correlation between concentration of PTX3 and painful erections. IL-6 concentrations were significantly higher in patients with erectile dysfunction. IL-6 and PTX3 levels showed no correlation with age, serum C-reactive protein, degree of curvature, and disease duration. IL-6 trans-signaling and PTX3 amplification at the site of inflammation could have a role in pathophysiological mechanisms of PD. Biological drugs may be used for treatment during the acute phase of the disease based on this mechanism.

The SMS, Phone, and medical Examination sports injury surveillance system is a feasible and valid approach to measuring handball exposure, injury occurrence, and consequences in elite youth sport.

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Møller, M; Wedderkopp, N; Myklebust, G; Lind, M; Sørensen, H; Hebert, J J; Attermann, J

2018-04-01

Current methods of sports injury surveillance are limited by lack of medical validation of self-reported injuries and/or incomplete information about injury consequences beyond time loss from sport. The aims of this study were to (a) evaluate the feasibility of the SMS, Phone, and medical Examination injury surveillance (SPEx) system (b) to evaluate the proportion of injuries and injury consequences reported by SPEx when compared to outcomes from a modified version of the Oslo Sports Trauma Research Centre (OSTRC) Overuse Injury Questionnaire. We followed 679 elite adolescent handball players over 31 weeks using the SPEx system. During the last 7 weeks, we also implemented a modified OSTRC questionnaire in a subgroup of 271 players via telephone interviews. The weekly response proportions to the primary SPEx questions ranged from 85% to 96% (mean 92%). SMS responses were received from 79% of the participants within 1 day. 95% of reported injuries were classified through the telephone interview within a week, and 67% were diagnosed by medical personnel. Comparisons between reported injuries from SPEx and OSTRC demonstrated fair (κ = 39.5% [25.1%-54.0%]) to substantial prevalence-adjusted bias-adjusted kappa (PABAK = 66.8% [95% CI 58.0%-75.6%]) agreement. The average injury severity score difference between SPEx and the OSTRC approach was -0.2 (95% CI -3.69-3.29) of possible 100 with 95% limits of agreement from(-14.81-14.41). These results support the feasibility and validity of the SPEx injury surveillance system in elite youth sport. Future studies should evaluate the external validity of SPEx system in different cohorts of athletes. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Does SMS Text Messaging Help or Harm Adults' Knowledge of Standard Spelling?

Science.gov (United States)

Powell, D.; Dixon, M.

2011-01-01

The recent increase in short messaging system (SMS) text messaging, often using abbreviated, non-conventional "textisms" (e.g. "2nite"), in school-aged children has raised fears of negative consequences of such technology for literacy. The current research used a paradigm developed by Dixon and Kaminska, who showed that exposure to phonetically…

Observation of the strongest 5s2 5p6 5d-(5s2 5p5 5d6s+5s25p6 7p) transitions in Au XI to Bi XV ions

International Nuclear Information System (INIS)

Churilov, S.S.; Joshi, Y.N.

2001-01-01

The spectra of gold till bismuth were studied in the 90-135 A region. Nine most intense lines belonging to the 5s 2 5p 6 5d-5s 2 5p 5 5d6s array were identified in Au XI to Bi XV ions. The 5s 2 5p 6 7p 2 P 3/2,1/2 levels in Au XI and the 5s 2 5p 6 7p 2 P 3/2 level in Hg XII were also identified. The observed wavelengths and intensities agree quite well with the Hartree-Fock calculations. (orig.)

Spectral analysis of 5s25p2(6p+6d+7s) configurations of Ba VI

International Nuclear Information System (INIS)

Sharma, M.K.; Tauheed, A.; Rahimullah, K.

2014-01-01

The sixth spectrum of barium (Ba VI) has been investigated with the aid of experimental recordings made on a 3-m normal incidence vacuum spectrograph of Antigonish laboratory (Canada) in the wavelength region 300–2080 Å using triggered spark as an excitation source. The spectral analysis has been extended considerably to include new configuration the 5s 2 5p 2 6p in odd parity matrix and the 5s 2 5p 2 6d and 5s 2 5p 2 7s configurations in even parity matrix. Previously reported levels of the ground configuration (5s 2 5p 3 ) and three lowest excited configurations the 5s5p 4 , 5s 2 5p 2 5d and 5s 2 5p 2 6s have been confirmed and the two unknown levels of the 5s 2 5p 2 5d configuration with J=9/2, have now been established through the identification of transitions from the 5s 2 5p 2 6p levels. All twenty one levels of the 5s 2 5p 2 6p configuration and twenty nine levels out of thirty six of the 5s 2 5p 2 6d and 5s 2 5p 2 7s configurations have now been established. Hartree–Fock calculations involving configuration interactions support the analyses. The accuracy of our wavelength measurement is ±0.005 Å for sharp lines. - Highlights: • The spectrum of Ba was recorded on a 3-m spectrograph with triggered spark source. • Atomic transitions for Ba VI were identified to established new energy levels. • CI calculations with relativistic corrections were made for theoretical predictions. • Weighted oscillator strength (gf) and transition probabilities (gA) were calculated

Higher proliferation of peritumoral endothelial cells to IL-6/sIL-6R than tumoral endothelial cells in hepatocellular carcinoma

International Nuclear Information System (INIS)

Zhuang, Peng-Yuan; Wang, Jian-Dong; Tang, Zhao-Hui; Zhou, Xue-Ping; Quan, Zhi-Wei; Liu, Ying-Bin; Shen, Jun

2015-01-01

This study aimed to explore the responses to the interleukin-6 (IL-6)/soluble interleukin-6 receptor (sIL-6R) complex in peritumoral endothelial cells (PECs) and tumor endothelial cells (TECs), as well as determine the signaling pathways in the angiogenesis of hepatocellular carcinoma (HCC). The expression of IL-6, IL-6R, gp130, CD68, HIF-1α, and microvessel density (MVD) were assessed with an orthotopic xenograft model in nude mice. ECs were incubated under hypoxic conditions to detect IL-6 and gp130. The proliferation of PECs and TECs in the presence of IL-6 and sIL-6R, as well as the expression of gp130, JAK2/STAT3, PI3K/AKT in endothelial cells were measured. Peritumoral IL-6, IL-6R, gp130, CD68, and HIF-1α expression, as well as MVD, gradually increased during tumor growth. Hypoxia could directly induce IL-6 expression, but not gp130 in PECs. The co-culture of IL-6/sIL-6R induced much higher PEC proliferation and gp130 expression, as well as the elevated phosphorylation of JAK2 and STAT3, however not the phosphorylation of PI3K and AKT. PECs exhibited higher proliferation in response to IL-6/sIL-6R co-treatment compared with TECs in HCC via the up-regulation of gp130 /JAK2/STAT3. PEC and its associated peritumoral angiogenesis microenvironment may be a potential novel target for anti-angiogenic treatment. The online version of this article (doi:10.1186/s12885-015-1763-2) contains supplementary material, which is available to authorized users

STS-37 crewmembers train in JSC's FB shuttle mission simulator (SMS)

Science.gov (United States)

1991-01-01

STS-37 Commander Steven R. Nagel (left) and Mission Specialist (MS) Jerry L. Ross rehearse some of their scheduled duties on the flight deck of JSC's fixed-based (FB) shuttle mission simulator (SMS) located in the Mission Simulation and Training Facility Bldg 5. During the unsuited simulation, Nagel reviews checklist while seated at the commanders station as Ross looks on from the pilots station.

Health-related quality of life improvement via telemedicine for epilepsy: printed versus SMS-based education intervention.

Science.gov (United States)

Lua, Pei Lin; Neni, Widiasmoro Selamat

2013-10-01

Improving health-related quality of life (HRQoL) among people with epilepsy (PWE) has become the focus of various treatment programmes and behavioural interventions which continue to be challenging to both patients and healthcare professionals. To investigate the impact of SMS-based epilepsy education programme on PWE's HRQoL status and to determine the predictors for good HRQoL. Eligible epilepsy out-patients from three public hospitals in East Coast Peninsular Malaysia were randomized into two groups: intervention (IG) and control (CG). Patients in the CG were supplied with only printed epilepsy educational module, while those in the IG additionally received short message service (SMS) from the Mobile Epilepsy Educational System (MEES). The Malay Quality of Life in Epilepsy Inventory-30 (MQOLIE-30) was utilized for HRQoL assessment. Descriptive statistics, paired t test, analysis of covariance and multiple logistic regression were employed for data analyses (SPSS 16). One hundred and forty-four PWE were recruited for the study (age = 30.5 ± 11.8; unmarried = 60.4 %; education level ≤ SPM/Cambridge O' level = 76.4 %; illness duration > 5 years = 51.1 %). After controlling for possible confounders, IG exhibited positive changes in HRQoL profile compared to CG particularly in Seizure Worry, Overall Quality of Life, Emotional Well-Being, Social Functioning and Overall Score (p < 0.05). After adjusting for covariates, being employed and receiving additional SMS-based epilepsy education programme emerged as the significant predictors of good HRQoL among PWE. Receiving continuous SMS-based epilepsy information from the MEES seemed to generate positive impacts on PWE's overall HRQoL. This study has provided a basis for future innovations to inspire efforts in ensuring the welfare and HRQoL of PWE and their families.

Teaching L2 vocabulary through SMS language: some didactic guidelines

OpenAIRE

López Rúa, Paula

2007-01-01

This article focuses on texting or SMS language, which is nowadays the most popular means of communication for a whole generation of mobile phone users. The introductory section comprises a parameter-based description of texting and a brief explanation of the features shared with other modalities of text-based electronic communication, after which the article provides an overview of the linguistic peculiarities of the system, i.e. its shortening mechanisms. It is suggested that an incursion i...

Prolonged activation of S6K1 does not suppress IRS or PI-3 kinase signaling during muscle cell differentiation

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MacKenzie Matthew G

2010-05-01

Full Text Available Abstract Background Myogenesis in C2C12 cells requires the activation of the PI3K/mTOR signaling pathways. Since mTOR signaling can feedback through S6K1 to inhibit the activation of PI3K, the aim of this work was to assess whether feedback from S6K1 played a role in myogenesis and determine whether siRNA mediated knockdown of S6K1 would lead to an increased rate of myotube formation. Results S6K1 activity increased in a linear fashion following plating and was more than 3-fold higher after Day 3 of differentiation (subconfluent = 11.09 ± 3.05, Day 3 = 29.34 ± 3.58. IRS-1 levels tended to increase upon serum withdrawal but decreased approximately 2-fold (subconfluent = 0.88 ± 0.10, Day 3 = 0.42 ± 0.06 3 days following differentiation whereas IRS-2 protein remained stable. IRS-1 associated p85 was significantly reduced upon serum withdrawal (subconfluent = 0.86 ± 0.07, Day 0 = 0.31 ± 0.05, remaining low through day 1. IRS-2 associated p85 decreased following serum withdrawal (subconfluent = 0.96 ± 0.05, Day 1 = 0.56 ± 0.08 and remained suppressed up to Day 3 following differentiation (0.56 ± 0.05. Phospho-tyrosine associated p85 increased significantly from subconfluent to Day 0 and remained elevated throughout differentiation. siRNA directed against S6K1 and S6K2 did not result in changes in IRS-1 levels after either 48 or 96 hrs. Furthermore, neither 48 nor 96 hrs of S6K1 knockdown caused a change in myotube formation. Conclusions Even though S6K1 activity increases throughout muscle cell differentiation and IRS-1 levels decrease over this period, siRNA suggests that S6K1 is not mediating the decrease in IRS-1. The decrease in IRS-1/2 associated p85 together with the increase in phospho-tyrosine associated p85 suggests that PI3K associates primarily with scaffolds other than IRS-1/2 during muscle cell differentiation.

Development and Evaluation of the Biogenic Emissions Inventory System (BEIS) Model v3.6

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We have developed new canopy emission algorithms and land use data for BEIS v3.6. Simulations with BEIS v3.4 and BEIS v3.6 in CMAQ v5.0.2 are compared these changes to the Model of Emissions of Gases and Aerosols from Nature (MEGAN) and evaluated the simulations against observati...

STS-31 crewmembers review checklist with instructor on JSC's FB-SMS middeck

Science.gov (United States)

1988-01-01

STS-31 Discovery, Orbiter Vehicle (OV) 103, Mission Specialist (MS) Bruce McCandless II (left) and Pilot Charles F. Bolden (right) discuss procedures with a training instructor on the middeck of JSC's fixed-based (FB) Shuttle Mission Simulator (SMS). The three are pointing to a checklist during this training simulation in the Mission Simulation and Training Facility Bldg 5.

STS-26 MS Lounge in fixed based (FB) shuttle mission simulator (SMS)

Science.gov (United States)

1988-01-01

STS-26 Discovery, Orbiter Vehicle (OV) 103, Mission Specialist (MS) John M. Lounge, wearing comunications kit assembly headset and crouched on the aft flight deck, performs checklist inspection during training session. The STS-26 crew is training in the fixed base (FB) shuttle mission simulator (SMS) located in JSC Mission Simulation and Training Facility Bldg 5.

The first quinary rare earth thiophosphates. Cs{sub 5}Ln{sub 3}X{sub 3}(P{sub 2}S{sub 6}){sub 2}(PS{sub 4}) (Ln = La, Ce, X = Br, Cl) and the quasi-quaternary Cs{sub 10}Y{sub 4}Cl{sub 10}(P{sub 2}S{sub 6}){sub 3}

Energy Technology Data Exchange (ETDEWEB)

Schoop, Leslie Mareike; Eger, Roland; Nuss, Juergen; Pielnhofer, Florian [Max Planck Institute for Solid State Research, Stuttgart (Germany); Lotsch, Bettina Valeska [Max Planck Institute for Solid State Research, Stuttgart (Germany); Nanosystems Initiative Munich (NIM) and Center for Nanoscience, Muenchen (Germany)

2017-12-13

We report the first examples of quinary rare earth thiophosphates with a fully ordered cation and anion distribution, Cs{sub 5}Ln{sub 3}X{sub 3}(P{sub 2}S{sub 6}){sub 2}(PS{sub 4}), (Ln = La, Ce and X = Br, Cl) as well as the quasi-quaternary Cs{sub 10}Y{sub 4}Cl{sub 10}(P{sub 2}S{sub 6}){sub 3}. These four new compounds crystallize in three different, unknown structure types. The yellowish, transparent, brittle Cs{sub 5}Ce{sub 3}Br{sub 3}(P{sub 2}S{sub 6}){sub 2}(PS{sub 4}) crystallizes in the orthorhombic space group Pnma (no. 62) with a = 13.276(3), b = 14.891(3), c = 19.593(4) Aa, and V = 3873(1) Aa{sup 3} in a novel structure type. Colorless crystals of Cs{sub 5}La{sub 3}Br{sub 3}(P{sub 2}S{sub 6}){sub 2}(PS{sub 4}) and Cs{sub 5}La{sub 3}Cl{sub 3}(P{sub 2}S{sub 6}){sub 2}(PS{sub 4}) are isotypic and were obtained in the monoclinic space group P2{sub 1}/m (no. 11) with a = 9.715(2), b = 14.310(3), c = 13.685(3) Aa, β = 100.16(3) and V = 1873(1) Aa{sup 3} and a = 9.513(2), b = 14.182(3), c = 13.699(3) Aa, β = 99.39(3) and V = 1823(1) Aa{sup 3}, respectively. Both structures contain isolated hexathiohypodiphosphate(IV) [P{sub 2}S{sub 6}]{sup 4-} and thiophosphate [PS{sub 4}]{sup 3-} units that are arranged alternately in layers. Cs{sub 10}Y{sub 4}Cl{sub 10}(P{sub 2}S{sub 6}){sub 3} crystallizes in colorless transparent platelets in the orthorhombic space group Pnnm (no. 58) with a = 13.153(3), b = 28.964(6), c = 7.780(2) Aa, and V = 2964(1) Aa{sup 3}. The structure is composed of isolated [P{sub 4/2}S{sub 6}]{sup 4-} octahedra containing four half occupied P positions surrounded octahedrally by sulfur. We show with Raman scattering that this disordered thiophosphate anion shows a Raman spectrum that is distinct from spectra published for other literature-known thiophosphate anions. (copyright 2017 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

Weighted f-values, A-values, and line strengths for the E1 transitions among 3d6, 3d54s, and 3d54p levels of Fe III

International Nuclear Information System (INIS)

Deb, Narayan C.; Hibbert, Alan

2009-01-01

Weighted oscillator strengths, weighted radiative rates, and line strengths for all the E1 transitions between 285 fine-structure levels belonging to the 3d 6 , 3d 5 4s, and 3d 5 4p configurations of Fe III are presented, in ascending order of wavelength. Calculations have been undertaken using the general configuration interaction (CI) code CIV3. The large configuration set is constructed by allowing single and double replacements from any of 3d 6 , 3d 5 4s, 3d 5 4p, and 3d 5 4d configurations to nl orbitals with n≤5,l≤3 as well as 6p. Additional selective promotions from 3s and 3p subshells are also included in the CI expansions to incorporate the important correlation effects in the n=3 shell. Results of some strong transitions between levels of 3d 6 , 3d 5 4s, and 3d 5 4p configurations are also presented and compared with other available calculations. It is found that large disagreements occur in many transitions among the existing calculations

Photo-induced effects of the virgin Ge_2_4_._9Sb_1_1_._6S_6_3_._5 film

International Nuclear Information System (INIS)

Knotek, P.; Tichy, L.; Kutalek, P.

2015-01-01

Amorphous Ge_2_4_._9Sb_1_1_._6S_6_3_._5 film was prepared through thermal evaporation. A blue shift of the optical band gap by approximately 100 meV was observed as a result of self-bleaching process of protected film aged for two years. The magnitude of the light induced blue shift of the optical band of the virgin film is primarily dependent on the light penetration depth and on the light intensity. The kinetics of photo-bleaching follows the stretch exponential function with a formal rate of bleaching depending on the light intensity while the saturated state is independent from the light intensity. The far infrared spectra indicate that ageing, illumination by over-band gap-photons and annealing of the virgin film are mainly accompanied by the film network ordering. Illumination by UV light photons led to a blue shift accompanied by the significant oxidation as evidenced by the results of the far infrared spectra and the energy dispersive analysis. - Highlights: • “Giant” photo-induced effects in virgin Ge_2_4_._9Sb_1_1_._6S_6_3_._5 film • The role of the film thickness, the wavelengths and intensity of excitation photons • The changes of the photo-sensitivity due to the self-ageing process • The high-intensity illumination (> 10 W/cm"2) led to the different processes

Fisetin inhibits human melanoma cell growth through direct binding to p70S6K and mTOR: findings from 3-D melanoma skin equivalents and computational modeling.

Science.gov (United States)

Syed, Deeba N; Chamcheu, Jean-Christopher; Khan, Mohammad Imran; Sechi, Mario; Lall, Rahul K; Adhami, Vaqar M; Mukhtar, Hasan

2014-06-01

The incidence of melanoma continues to rise. Inspite of treatment advances, the prognosis remains grim once the disease has metastasized, emphasizing the need to explore additional therapeutic strategies. One such approach is through the use of mechanism-based dietary intervention. We previously showed that the flavonoid fisetin inhibits melanoma cell proliferation, in vitro and in vivo. Here, we studied fisetin-mediated regulation of kinases involved in melanoma growth and progression. Time-course analysis in 3-D melanoma constructs that transitioned from radial to vertical growth showed that fisetin treatment resulted in significant decrease in melanocytic lesions in contrast to untreated controls that showed large tumor nests and invading disseminated cells. Further studies in melanoma cultures and mouse xenografts showed that fisetin-mediated growth inhibition was associated with dephosphorylation of AKT, mTOR and p70S6K proteins. In silico modeling indicated direct interaction of fisetin with mTOR and p70S6K with favorable free energy values. These findings were validated by cell-free competition assays that established binding of fisetin to p70S6K and mTOR while little affinity was detected with AKT. Kinase activity studies reflected similar trend with % inhibition observed for p70S6K and mTOR at lower doses than AKT. Our studies characterized, for the first time, the differential interactions of any botanical agent with kinases involved in melanoma growth and demonstrate that fisetin inhibits mTOR and p70S6K through direct binding while the observed inhibitory effect of fisetin on AKT is mediated indirectly, through targeting interrelated pathways. Published by Elsevier Inc.

Integrated Safety Culture Model and Application

Institute of Scientific and Technical Information of China (English)

汪磊; 孙瑞山; 刘汉辉

2009-01-01

A new safety culture model is constructed and is applied to analyze the correlations between safety culture and SMS. On the basis of previous typical definitions, models and theories of safety culture, an in-depth analysis on safety culture's structure, composing elements and their correlations was conducted. A new definition of safety culture was proposed from the perspective of sub-cuhure. 7 types of safety sub-culture, which are safety priority culture, standardizing culture, flexible culture, learning culture, teamwork culture, reporting culture and justice culture were defined later. Then integrated safety culture model (ISCM) was put forward based on the definition. The model divided safety culture into intrinsic latency level and extrinsic indication level and explained the potential relationship between safety sub-culture and all safety culture dimensions. Finally in the analyzing of safety culture and SMS, it concluded that positive safety culture is the basis of im-plementing SMS effectively and an advanced SMS will improve safety culture from all around.

AF-6 Protects Against Dopaminergic Dysfunction and Mitochondrial Abnormalities in Drosophila Models of Parkinson’s Disease

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Adeline H. Basil

2017-08-01

Full Text Available Afadin 6 (AF-6 is an F-actin binding multidomain-containing scaffolding protein that is known for its function in cell-cell adhesion. Interestingly, besides this well documented role, we recently found that AF-6 is a Parkin-interacting protein that augments Parkin/PINK1-mediated mitophagy. Notably, mutations in Parkin and PINK1 are causative of recessively inherited forms of Parkinson’s disease (PD and aberrant mitochondrial homeostasis is thought to underlie PD pathogenesis. Given the novel role of AF-6 in mitochondrial quality control (QC, we hypothesized that AF-6 overexpression may be beneficial to PD. Using the Drosophila melanogaster as a model system, we demonstrate in this study that transgenic overexpression of human AF-6 in parkin and also pink1 null flies rescues their mitochondrial pathology and associated locomotion deficit, which results in their improved survival over time. Similarly, AF-6 overexpression also ameliorates the pathological phenotypes in flies expressing the Leucine Rich Repeat Kinase 2 (LRRK2 G2019S mutant, a mutation that is associated with dominantly-inherited PD cases in humans. Conversely, when endogenous AF-6 expression is silenced, it aggravates the disease phenotypes of LRRK2 mutant flies. Aside from these genetic models, we also found that AF-6 overexpression is protective against the loss of dopaminergic neurons in flies treated with rotenone, a mitochondrial complex I inhibitor commonly used to generate animal models of PD. Taken together, our results demonstrate that AF-6 protects against dopaminergic dysfunction and mitochondrial abnormalities in multiple Drosophila models of PD, and suggest the therapeutic value of AF-6-related pathways in mitigating PD pathogenesis.

Assessment of knowledge about healthy heart habits in urban and rural population of Punjab after SMS campaign-A cross-sectional study.

Science.gov (United States)

Mohan, Bishav; Sharma, Sarit; Sharma, Shruti; Kaushal, Dinesh; Singh, Bhupinder; Takkar, Shibba; Aslam, Naved; Goyal, Abhishek; Wander, Gurpreet S

The prevalence of cardiovascular diseases (CVD) is increasing in developing countries but the awareness regarding prevention and treatment of these diseases is still low. Therefore the present study was conducted with the aim of imparting health education regarding certain changes in lifestyle and dietary habits among general population through the use of short message service (SMS) that may lead to improved knowledge about prevention of cardiovascular diseases. This cross-sectional study was conducted over a period of seven months. In the first phase, health education messages were sent through SMS to about 40,000 individuals from urban and rural population in Punjab. Twenty eight messages were sent to each individual and hence more than eleven lakh messages were sent over a period of six months. A questionnaire containing 11 questions based on these health education SMS was generated. Every 40th individual enrolled in the study was contacted on phone, and their responses noted. The data so collected was analyzed for correct responses. Complete responses could be obtained from 800 participants (males: 561 and females: 239). The participants giving correct responses to different questions ranged from 43% to 94%. Majority of participants could retain knowledge about many aspects of healthy heart habits provided by SMS except for topics concerning foods to be avoided, target for normal BP and precautions to be taken before BP measurement. Health related information imparted through SMS can act as a very effective tool for disseminating knowledge about prevention of heart diseases in general population. Copyright © 2017 Cardiological Society of India. Published by Elsevier B.V. All rights reserved.

The effectiveness of SMS Reminders and the impact of patient characteristics on missed appointments in a public dental outpatient clinic

OpenAIRE

Emilia Bellucci; Lasitha Dharmasena; Lemai Nguyen; Hanny Calache

2017-01-01

This paper reports on the Failure To Attend (FTA) rate of appointments as well as patients following the implementation of SMS reminders in a public dental outpatient service.  Given the ineffectiveness of the intervention and a highly representative patient’s profile, this paper identifies the demographic characteristics of patients who miss all of their appointments.  Data on appointment attendance, patient demographics and dental service type was collected over a time period of 46 consecut...

The Prototype of Real-time Object Detection System Based on SMS

Directory of Open Access Journals (Sweden)

M. Hana Mirza

2010-08-01

Full Text Available The powerful algorithm to detect object movement in development of room monitoring system is very urgent. The commond algorithm needs complex computation. In this research, the prototype of real-time object detection system using simple algorithm is developed, i.e. using the determination of the max noise/pixel value and the tolerance threshold of image accurately, and then the system automatically send a SMS (short message services to user when the object movement is detected. The developed prototype used a Logitech QuickCam webcam, a Siemens C45 mobile phone and a data cable, and the Borland Delphi 7 with additional components and Serial PortNG Tvideo as system software. The application also includes a database to store the captured images whenever object movement is detected. The test results by varying conditions of light intensities using a 5-watt light bulb, fluorescent lamp 20 and 40 watts indicate that the application is able to automatically detect the presence of moving objects with 100% success rate. The success rate is strongly influenced by the determination of the max noise/pixel value and the tolerance threshold during system configuration. This application is also capable of sending SMS automatically when the system detects a moving object with an average time of 8.35 seconds.

Rancang Bangun Sistem Informasi Pelayanan Kesehatan Berbasis Customer Relationship Management Menggunakan Teknologi Short Message Service (SMS

Directory of Open Access Journals (Sweden)

Trismianto Asmo Sutrisno Sutrisno

2014-02-01

Full Text Available Recently, there are many hospitals as the health-care services choose to use the concept of Customer Relationship Management (CRM to build the trust bridges between the hospitals and their patients. The implementation of CRM in health caring, especially for pregnant women needs to do; such as the delivery of information related to the pregnant women to get antenatal care as the scheduled or pregnant women desire to obtain information dealing with their pregnancy. The irrelevant, slow and inaccurate information can cause the health care services given to the patients are not optimal, so that they can reduce patients’ loyalty toward the health-care services. This research resulted health care information system based on Customer Relationship Management using Short Message Service (SMS technology with case study of health care for pregnant women. The resulted information system is produced by the System Development Life Cycle methodology using the Waterfall model. One of the features produced is the pregnant women will receive a confirmation SMS to obtain antenatal care with a schedule until 28 weeks of their pregnancy check up every four weeks, 28-36 weeks of their pregnancy check up every two weeks, and 36-40 weeks of their pregnancy check up once a week.   Keywords: Pregnant Women, Antenatal Care, Customer Relationship Management, Short Message Service

Chemoselective reduction of 1,4,6-cholestatrien-3-one and 1,4,6-androstatriene-3,17-dione by various hydride reagents.

Science.gov (United States)

Kim, Eunjeong; Ma, Eunsook

2007-04-01

The chemoselectivity of rigid cyclic alpha,beta-unsaturated carbonyl group on the reducing agents was influenced by the ring size and steric factor. Cholesterol (cholest-5-en-3beta-ol) and dehydroepiandrosterone (DHEA) were oxidized with 2,3-dichloro-5,6-dicyano-1,4-benzoquinone to form 1,4,6-cholestatrien-3-one and 1,4,6-androstatriene-3,17-dione. They were reduced with NaBH(4), lithium tri-sec-butylborohydride (l-Selectride), LiAlH(4), 9-borabicyclo[3.3.1]nonane (9-BBN), lithium triethylborohydride (Super-hydride), and BH(3) x (CH(3))(2)S in various conditions, respectively. Reduction of 1,4,6-cholestatrien-3-one and 1,4,6-androstatriene-3,17-dione by NaBH(4) (4 equiv.) produced 4,6-cholestadien-3beta-ol and 4,6-androstadiene-3beta,17beta-diol, respectively. Reduction by l-Selectride (12 equiv.) afforded 4,6-cholestadien-3alpha-ol and 4,6-androstadiene-3alpha,17beta-diol, chemoselectively. Reaction with Super-hydride (12 equiv.) produced 4,6-cholestadien-3-one and 3-oxo-4,6-androstadien-17beta-ol. Reduction of 1,4,6-cholestatrien-3-one by 9-BBN (14 equiv.) produced 1,4,6-cholestatrien-3alpha-ol, but 1,4,6-androstatriene-3,17-dione was not reacted with 9-BBN in the reaction conditions. Reaction of LiAlH(4) (6 equiv.) formed 4,6-cholestadien-3beta-ol and 3-oxo-1,4,6-androstatrien-17beta-ol. Reduction of 1,4,6-cholestatrien-3-one by BH(3) x (CH(3))(2)S (11 equiv.) gave cholestane as major compound and unlike reactivity of cholesterol, 1,4,6-androstatriene-3,17-dione by 8 equiv. of BH(3) x (CH(3))(2)S formed 3-oxo-1,4,6-androstatrien-17beta-ol. LiAlH(4) and BH(3) x (CH(3))(2)S showed relatively low chemoselectivity.

STS-26 crew on fixed based (FB) shuttle mission simulator (SMS) flight deck

Science.gov (United States)

1988-01-01

STS-26 Discovery, Orbiter Vehicle (OV) 103, Commander Frederick H. Hauck (left) and Pilot Richard O. Covey review checklists in their respective stations on the foward flight deck. The STS-26 crew is training in the fixed base (FB) shuttle mission simulator (SMS) located in JSC Mission Simulation and Training Facility Bldg 5.

No-carrier-added (NCA) synthesis of 6-[18F]fluoro-L-DOPA using 3,5,6,7,8,8a-hexahydro-7,7,8a-trimethyl-[6S-(6α, 8α, 8αβ)]-6,8-methano-2H-1,4-benzoxazin-2-one

International Nuclear Information System (INIS)

Horti, A.; Yale Univ., West Haven, CT; Redmond, D.E. Jr.; Soufer, R.

1995-01-01

3,5,6,7,8,8a-Hexahydro-7,7,8a-trimethyl-[6S-(6α,8α , 8αβ)]-6,8-methano-2H-1,4-benzoxazino-2-one (2) was investigated as chiral auxiliary for asymmetric NCA nucleophilic synthesis of 6-[ 18 F]Fluoro-L-DOPA. Direct condensation of 3,4-dimethoxy-2-[ 18 F]fluorobenzaldehyde (1a) or 6-[ 18 F]fluoro-piperonal (1b) in the presence of NaH with 2 gave the corresponding [ 18 F]-3-[(2-fluorophenyl)methylene]-3,5,6,7,8,8a-hexahydro-7,7,8 a-trimethyl-[6S-(3Z,3α,6α,8α,8αβ)]-6, 8-methano-2H-1,4-benzoxazin-2-one derivative 3a or 3b as a single stereoisomer. L-Selectride promoted hydrogenation of the olefinic double bond of these derivatives, in presence of tertbutyl alcohol, afforded the corresponding [ 18 F]-3-[(2-fluorophenyl) methyl]-3,5,6,7,8,8a-hexahydro-7,7,8a-trimethyl-[3S-(3α, 6α, 8α8αβ)]-6,8-methano-2H-1,4-benzoxazin-2-one derivatives (4a,b) without affecting the orientation of diasterofacial discrimination. Deprotection of the derivatives 4a,b yielded 6-[ 18 F]fluoro-L-DOPA (e.e. >90%, 3% radiochemical yield (EOB), total synthesis time 125 min, specific activity >2000 mCi/μmol). Direct deprotection/reduction of the compounds 3a,b provides the enantiomeric mixture of 6-[ 18 F]fluoro-D,L-DOPA (10-12% radiochemical yield) and, after chiral separation, 6-[ 18 F]fluoro-L-DOPA (e.e. 98%, 4-5% radiochemical yield). (author)

Crystal structure of 2-[(3aS,6R-3,3,6-trimethyl-3,3a,4,5,6,7-hexahydro-2H-indazol-2-yl]thiazol-4(5H-one

Directory of Open Access Journals (Sweden)

Abdellah N'ait Ousidi

2016-03-01

Full Text Available The title compound, C13H19N3OS, is a new thiazolidin-4-one derivative prepared and isolated as the pure (3aS,6R-diastereisomer from (R-thiosemicarbazone pulegone. It crystallized with two independent molecules (A and B in the asymmetric unit. The compound is composed of a hexhydroindazole ring system (viz. a five-membered dihydropyrazole ring fused to a cyclohexyl ring with a thiazole-4-one ring system attached to one of the pyrazole N atoms (at position 2. The overall geometry of the two molecules differs slightly, with the mean planes of the pyrazole and thiazole rings being inclined to one another by 10.4 (1° in molecule A and 0.9 (1° in molecule B. In the crystal, the A and B molecules are linked via C—H...O hydrogen bonds, forming slabs parallel to the ab plane. There are C—H...π interactions present within the layers, and between the layers, so forming a three-dimensional structure.

Adenovirus-mediated sphingomyelin synthase 2 increases atherosclerotic lesions in ApoE KO mice

Directory of Open Access Journals (Sweden)

Zhao Yarui

2011-01-01

Full Text Available Abstract Background Sphingomyelin synthase 2 (SMS2 contributes to de novo sphingomyelin (SM biosynthesis. Its activity is related to SM levels in the plasma and the cell membrane. In this study, we investigated the possibility of a direct relationship between SMS and atherosclerosis. Methods The Adenovirus containing SMS2 gene was given into 10-week ApoE KO C57BL/6J mice by femoral intravenous injection. In the control group, the Adenovirus containing GFP was given. To confirm this model, we took both mRNA level examination (RT-PCR and protein level examination (SMS activity assay. Result We generated recombinant adenovirus vectors containing either human SMS2 cDNA (AdV-SMS2 or GFP cDNA (AdV-GFP. On day six after intravenous infusion of 2 × 1011 particle numbers into ten-week-old apoE KO mice, AdV-SMS2 treatment significantly increased liver SMS2 mRNA levels and SMS activity (by 2.7-fold, 2.3-fold, p Conclusions Our results present direct morphological evidence for the pro-atherogenic capabilities of SMS2. SMS2 could be a potential target for treating atherosclerosis.

STS-36 crewmembers train in JSC's FB shuttle mission simulator (SMS)

Science.gov (United States)

1989-01-01

STS-36 Mission Specialist (MS) David C. Hilmers, seated on the aft flight deck, discusses procedures with Commander John O. Creighton (left) and Pilot John H. Casper during a simulation in JSC's Fixed Based (FB) Shuttle Mission Simulator (SMS). Casper reviews a checklist at the pilots station on the forward flight deck. The crewmembers are rehearsing crew cabin activities for their upcoming Department of Defense (DOD) mission aboard Atlantis, Orbiter Vehicle (OV) 104.

(S)-2-Amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic acid, a potent and selective agonist at the GluR5 subtype of ionotropic glutamate receptors. Synthesis, modeling, and molecular pharmacology

DEFF Research Database (Denmark)

Brehm, Lotte; Greenwood, Jeremy R; Hansen, Kasper B

2003-01-01

)propionic acid (AMPA) but inactive at NMDA receptors. However, 4-AHCP was found to be much weaker than AMPA as an inhibitor of [(3)H]AMPA binding and to have limited effect in a [(3)H]kainic acid binding assay using rat cortical membranes. To shed light on the mechanism(s) underlying this quite enigmatic......, activated cloned AMPA receptor subunits GluR1o, GluR3o, and GluR4o with EC(50) values in the range 4.5-15 microM and the coexpressed kainate-preferring subunits GluR6 + KA2 (EC(50) = 6.4 microM). Compound 6, but not 7, proved to be a very potent agonist (EC(50) = 0.13 microM) at the kainate-preferring GluR5...... subunit, equipotent with (S)-2-amino-3-(5-tert-butyl-3-hydroxyisothiazol-4-yl)propionic acid [(S)-Thio-ATPA, 4] and almost 4 times more potent than (S)-2-amino-3-(5-tert-butyl-3-hydroxyisoxazol-4-yl)propionic acid [(S)-ATPA, 3]. Compound 6 thus represents a new structural class of GluR5 agonists...

The Bi{sup 3+} 6s and 6p electron binding energies in relation to the chemical environment of inorganic compounds

Energy Technology Data Exchange (ETDEWEB)

Awater, Roy H.P., E-mail: R.H.P.Awater@tudelft.nl; Dorenbos, Pieter

2017-04-15

This paper provides an overview and interpretation of the spectroscopic data of the Bi{sup 3+} activator ion in 117 different inorganic compounds. The energies of the metal-to-metal charge transfer and the interconfigurational transitions of Bi{sup 3+} were collected from the archival literature. Using these energies, in combination with the electron binding energies in the host conduction and valence band, the binding energies in the 6s ground state and 6p excited state were determined relative to the vacuum level. The locations of the Bi{sup 3+} energy levels within the forbidden gap of the host compound provides valuable insight in the physical properties of the Bi{sup 3+} activator ion in different compounds.

Rate Constant for the Reaction CH3 + CH3 Yields C2H6 at T = 155 K and Model Calculation of the CH3 Abundance in the Atmospheres of Saturn and Neptune

Science.gov (United States)

Cody, Regina J.; Romani, Paul N.; Nesbitt, Fred L.; Iannone, Mark A.; Tardy, Dwight C.; Stief, Louis J.

2003-01-01

The column abundances of CH3 observed by the Infrared Space Observatory (ISO) satellite on Saturn and Neptune were lower than predicted by atmospheric photochemical models, especially for Saturn. It has been suggested that the models underestimated the loss of CH3 due to poor knowledge of the rate constant k of the CH3 + CH3 self-reaction at the low temperatures and pressures of these atmospheres. Motivated by this suggestion, we undertook a combined experimental and photochemical modeling study of the CH3 + CH3 reaction and its role in determining planetary CH3 abundances. In a discharge flow-mass spectrometer system, k was measured at T = 155 K and three pressures of He. The results in units of cu cm/molecule/s are k(0.6 Torr) = 6.82 x 10(exp -11), k(1.0 Torr) = 6.98 x 10(exp -11), and k(1.5 Torr) = 6.91 x 10(exp -11). Analytical expressions for k were derived that (1) are consistent with the present laboratory data at T = 155 K, our previous data at T = 202 K and 298 K, and those of other studies in He at T = 296-298 K and (2) have some theoretical basis to provide justification for extrapolation. The derived analytical expressions were then used in atmospheric photochemical models for both Saturn and Neptune. These model results reduced the disparity with observations of Saturn, but not with observations of Neptune. However, the disparity for Neptune is much smaller. The solution to the remaining excess CH3 prediction in the models relative to the ISO observations lies, to a large extent, elsewhere in the CH3 photochemistry or transport, not in the CH3 + CH3 rate.

Higgs phenomenology in the minimal S U (3 )L×U (1 )X model

Science.gov (United States)

Okada, Hiroshi; Okada, Nobuchika; Orikasa, Yuta; Yagyu, Kei

2016-07-01

We investigate the phenomenology of a model based on the S U (3 )c×S U (3 )L×U (1 )X gauge theory, the so-called 331 model. In particular, we focus on the Higgs sector of the model which is composed of three S U (3 )L triplet Higgs fields and is the minimal form for realizing a phenomenologically acceptable scenario. After the spontaneous symmetry breaking S U (3 )L×U (1 )X→S U (2 )L×U (1 )Y , our Higgs sector effectively becomes that with two S U (2 )L doublet scalar fields, in which the first- and the second-generation quarks couple to a different Higgs doublet from that which couples to the third-generation quarks. This structure causes the flavor-changing neutral current mediated by Higgs bosons at the tree level. By taking an alignment limit of the mass matrix for the C P -even Higgs bosons, which is naturally realized in the case with the breaking scale of S U (3 )L×U (1 )X much larger than that of S U (2 )L×U (1 )Y, we can avoid current constraints from flavor experiments such as the B0-B¯ 0 mixing even for the Higgs bosons masses that are O (100 ) GeV . In this allowed parameter space, we clarify that a characteristic deviation in quark Yukawa couplings of the Standard Model-like Higgs boson is predicted, which has a different pattern from that seen in two Higgs doublet models with a softly broken Z2 symmetry. We also find that the flavor-violating decay modes of the extra Higgs boson, e.g., H /A →t c and H±→t s , can be dominant, and they yield the important signature to distinguish our model from the two Higgs doublet models.

Beyond mere pill taking: SMS reminders for HIV treatment adherence delivered to mobile phones of clients in a community support network in Australia.

Science.gov (United States)

Mao, Limin; Buchanan, Andrew; Wong, Horas Tze Hoo; Persson, Asha

2018-01-15

SMS reminders sent to personal mobiles are increasingly used by clinical services to promote patient engagement, including adherence to antiretroviral treatment (ART) for HIV. From August to September 2015, a 6-week, randomised SMS reminder for ART adherence intervention was implemented among 98 HIV-positive clients of Australian's largest HIV charitable organisation located in Sydney. This was followed by a mixed-method evaluation, comprising a self-completed online survey and a one-to-one interview. Of the 62 survey participants, all being men, the majority were gay (85.5%) and living long-term with HIV (median year of HIV diagnosis = 1998). While everyone was on ART, a substantial proportion (n = 27, 43.5%) had interrupted treatment in the past. At the end of the intervention, based on the standard SMAQ measure, 82% had consistently adhered to ART in the previous week. While there was no statistically significant intervention effect, perceiving less stigma were independently associated with better ART adherence (adjusted odds ratio = 0.37; 95% CI 0.16-0.89; P = .026). Of the 11 interviewees, despite limited add-on effects on individual ART adherence, the campaign was well-received as a unique community support service. This study underscores the essential role of empowerment through enhancing disease self-management, increasing social support and reducing stigma, particularly for long-term HIV survivors. SMS messaging, part of mHealth, delivered by community services could have broader impacts on reducing health and social inequity. © 2018 John Wiley & Sons Ltd.

STS-26 MS Hilmers on fixed based (FB) shuttle mission simulator (SMS) middeck

Science.gov (United States)

1988-01-01

STS-26 Discovery, Orbiter Vehicle (OV) 103, Mission Specialist (MS) David C. Hilmers prepares to ascend a ladder representing the interdeck access hatch from the shuttle middeck to the flight deck. The STS-26 crew is training in the fixed base (FB) shuttle mission simulator (SMS) located in JSC Mission Simulation and Training Facility Bldg 5.

An AdS3 dual for minimal model CFTs

International Nuclear Information System (INIS)

Gaberdiel, Matthias R.; Gopakumar, Rajesh

2011-01-01

We propose a duality between the 2d W N minimal models in the large N't Hooft limit, and a family of higher spin theories on AdS 3 . The 2d conformal field theories (CFTs) can be described as Wess-Zumino-Witten coset models, and include, for N=2, the usual Virasoro unitary series. The dual bulk theory contains, in addition to the massless higher spin fields, two complex scalars (of equal mass). The mass is directly related to the 't Hooft coupling constant of the dual CFT. We give convincing evidence that the spectra of the two theories match precisely for all values of the 't Hooft coupling. We also show that the renormalization group flows in the 2d CFT agree exactly with the usual AdS/CFT prediction of the gravity theory. Our proposal is in many ways analogous to the Klebanov-Polyakov conjecture for an AdS 4 dual for the singlet sector of large N vector models.

Exploring the Υ(6S) → χ{sub bJ}φ and Υ(6S) → χ{sub bJ}ω hidden-bottom hadronic transitions

Energy Technology Data Exchange (ETDEWEB)

Huang, Qi; Wang, Bo; Liu, Xiang [Lanzhou University, School of Physical Science and Technology, Lanzhou (China); Lanzhou University and Institute of Modern Physics of CAS, Research Center for Hadron and CSR Physics, Lanzhou (China); Chen, Dian-Yong [Southeast University, Department of Physics, Nanjing (China); Matsuki, Takayuki [Tokyo Kasei University, Itabashi, Tokyo (Japan); Nishina Center, RIKEN, Theoretical Research Division, Wako, Saitama (Japan)

2017-03-15

In this work, we investigate the hadronic loop contributions to the Υ(6S) → χ{sub bJ}φ (J = 0, 1, 2) along with Υ(6S) → χ{sub bJ}ω (J=0, 1, 2) transitions. We predict that the branching ratios of Υ(6S) → χ{sub b0}φ, Υ(6S) → χ{sub b1}φ and Υ(6S) → χ{sub b2}φ are (0.68-4.62) x 10{sup -6}, (0.50-3.43) x 10{sup -6} and (2.22-15.18) x 10{sup -6}, respectively, and those of Υ(6S) → χ{sub b0}ω, Υ(6S) → χ{sub b1}ω and Υ(6S) → χ{sub b2}ω are (0.15-2.81) x 10{sup -3}, (0.63-11.68) x 10{sup -3}, and (1.08-20.02) x 10{sup -3}, respectively. Especially, some typical ratios, which reflect the relative magnitudes of the predicted branching ratios, are given, i.e., for Υ(6S) → χ{sub bJ}φ transitions, R{sup φ}{sub 10} = B[Υ(6S) → χ{sub b1}φ]/B[Υ(6S) → χ{sub b0}φ] ∼ 0.74, R{sup φ}{sub 20} = B[Υ(6S) → χ{sub b2}φ]/B[Υ(6S) → χ{sub b0}φ] ∼ 3.28, and R{sup φ}{sub 21} = B[Υ(6S) → χ{sub b2}φ]/B[Υ(6S) → χ{sub b1}φ] ∼ 4.43, and for Υ(6S) → χ{sub bJ}ω transitions, R{sup ω}{sub 10} = B[Υ(6S) → χ{sub b1}ω]/B[Υ(6S) → χ{sub b0}ω] ∼ 4.11, R{sup ω}{sub 20} = B[Υ(6S) → χ{sub b2}ω]/B[Υ(6S) → χ{sub b0}ω] ∼ 7.06, and R{sup ω}{sub 21} = B[Υ(6S) → χ{sub b2}ω]/B[Υ(6S) → χ{sub b1}ω] ∼ 1.72. With the running of BelleII in the near future, experimental measurement of these two kinds of transitions will be a potential research issue. (orig.)

Penerapan Safety Management System (SMS) Dan Kompetensi Pemandu Lalu Lintas Penerbangan

OpenAIRE

Melissa, Anaria Carini; Subagyo, Toto Hardiyanto; Suharno, Hadi; Majid, Suharto Abdul

2017-01-01

The objective of the research is to analyze the influence between Implementation of Safety Management System (SMS) and Competency of Air Traffic Controller towards Aviation Safety at Perum LPPNPI Main Branch JATSC. Type of research is quantitative research by means of surveys, where data obtained through a questionnaire that will be distributed On Air Traffic Controller Perum LPPNPI Main Branch JATSC. The population in this research is an Air Traffic Controller Perum LPPNPI Main Branch JAT...

Supersymmetric AdS6 solutions of type IIB supergravity

International Nuclear Information System (INIS)

Kim, Hyojoong; Kim, Nakwoo; Suh, Minwoo

2015-01-01

We study the general requirement for supersymmetric AdS 6 solutions in type IIB supergravity. We employ the Killing spinor technique and study the differential and algebraic relations among various Killing spinor bilinears to find the canonical form of the solutions. Our result agrees precisely with the work of Apruzzi et al. (JHEP 1411:099, 2014), which used the pure spinor technique. Hoping to identify the geometry of the problem, we also computed four-dimensional theory through the dimensional reduction of type IIB supergravity on AdS 6 . This effective action is essentially a non-linear sigma model with five scalar fields parametrizing SL(3,ℝ)/SO(2,1), modified by a scalar potential and coupled to Einstein gravity in Euclidean signature. We argue that the scalar potential can be explained by a subgroup CSO(1,1,1) ⊂SL(3,ℝ) in a way analogous to gauged supergravity

Synthesis and physico-chemical properties of (R,S)-6-ditrideuteriomethylamino-4,4-diphenylheptan-3-one hydrochloride (methadone-d6)

International Nuclear Information System (INIS)

Gerardy, B.M.; Poupaert, J.H.; Vandervorst, D.; Dumont, P.; Declerq, J.-P.; Meerssche, M. van; Portoghese, P.S.

1985-01-01

A reaction sequence is described to synthesize (R,S)-6-ditrideuteriomethylamino-4,4-diphenylheptan-3-one hydrochloride (methado-ne-d 6 .HC1) in 10.5% overall yield starting from dimethylamine-d 6 hydrochloride. While methadone-d 6 .HC1 had rather similar physicochemical properties compared to methadone.HC1 in the solid phase, a divergent behaviour was observed in solution (pKa, chromatographic and 13 C-NMR data). A higher basicity along with a more important hydrophilicity were observed for the d 6 -derivative. A 13 C-NMR study showed significant differences in the 13 C chemical shifts, which were attributed in part to the intrinsic nature of D itself and in part to a conformational perturbation. The longer duration of antinociceptive action, along with higher tsub(1/2) and clearance, and the depression of the metabolic N-demethylation process were the only biological properties modified by the deuteration. (author)

(Ph4P)S6—A Compound Containing the Cyclic Radical Anion S6.−

NARCIS (Netherlands)

Neumuller, F.; Schmock, R.; Kirmse, A.; Voigt, A.; Diefenbach, A.; Bickelhaupt, F.M.; Dehnicke, K.

2000-01-01

Two long S−S bonds link the two S3 fragments in the cyclic radical anion S6.−. This forms as orange‐red crystals with PPh4+ as the counterion in the reaction of sulfane with (tetraphenylphosphonium) hydrogen diazide. The anion has a chair conformation with C2h symmetry (see picture).

Biosynthesis of tert-butyl (3R,5S)-6-chloro-3,5-dihydroxyhexanoate by carbonyl reductase from Rhodosporidium toruloides in mono and biphasic media.

Science.gov (United States)

Liu, Zhi-Qiang; Wu, Lin; Zheng, Ling; Wang, Wen-Zhong; Zhang, Xiao-Jian; Jin, Li-Qun; Zheng, Yu-Guo

2018-02-01

tert-Butyl (3R,5S)-6-chloro-3,5-dihydroxyhexanoate ((3R,5S)-CDHH) is the key intermediate for synthesis of atorvastatin and rosuvastatin. Carbonyl reductase exhibits excellent activity toward tert-butyl (S)-6-chloro-5-hydroxy-3-oxohexanoate ((S)-CHOH) to synthesize (3R,5S)-CDHH. In this study, a whole cell biosynthesis reaction system to produce (3R,5S)-CDHH was constructed in organic solvents. A solution of 10% (v/v) Tween-80 was introduced to the reaction system as a co-solvent, which greatly enhanced biotransformation process, giving 98.9% yield, >99% ee and 1.8-fold higher space time yield in 5 h bioconversion of 1 M (S)-CHOH, compared with 98.7% yield and >99% ee in 9 h bioconversion of a purely aqueous reaction system. Moreover, a water-octanol biphasic reaction system was built and 20% of octanol was added as reservoir of substrate resulting in 98% yield, >99% ee and 4.08 mmol L -1  h -1  g -1 (wet cell weight) space time yield. This study paved a way for the whole cell biosynthesis of (3R,5S)-CDHH in mono and biphasic media. Copyright © 2017 Elsevier Ltd. All rights reserved.

Methane production and characteristics of the microbial community in the co-digestion of spent mushroom substrate with dairy manure.

Science.gov (United States)

Luo, Xiaosha; Yuan, Xufeng; Wang, Shiyu; Sun, Fanrong; Hou, Zhanshan; Hu, Qingxiu; Zhai, Limei; Cui, Zongjun; Zou, Yajie

2018-02-01

Spent mushroom substrate (SMS) is a potential biomass material generated during mushroom cultivation. In this study, the methane yield and microbial community resulting from co-digestion of SMS and dairy manure (DM) at different mixing ratios (0:4, 1:1, 3:1, and 1:3), were evaluated. Co-digestion analysis showed that the methane yield from the mixtures was 6%-61% higher than the yield from SMS or DM alone, indicating a synergistic effect of co-digestion of SMS with DM. For the SMS of F.velutipes (SFv) and P.erygii var. tuoliensis (SPt), co-digestion of DM/SMS at a ratio of 1:1 was optimal, but for the SMS of P. eryngi (SPe), co-digestion of DM/SMS at a ratio of 3:1 was ideal. The pH at all co-digestion ratios was in the range of 6.8-8.0, indicating that adding DM could increase the systemic buffering capacity. Methanosaetaceae was shown to be the predominant methanogens present during the co-digestion of DM/SMS. Copyright © 2017 Elsevier Ltd. All rights reserved.

EQ3/6, a software package for geochemical modeling of aqueous systems: Package overview and installation guide (Version 7.0)

Energy Technology Data Exchange (ETDEWEB)

Wolery, T.J.

1992-09-14

EQ3/6 is a software package for geochemical modeling of aqueous systems. This report describes version 7.0. The major components of the package include: EQ3NR, a speciation-solubility code; EQ6, a reaction path code which models water/rock interaction or fluid mixing in either a pure reaction progress mode or a time mode; EQPT, a data file preprocessor, EQLIB, a supporting software library; and five supporting thermodynamic data files. The software deals with the concepts of thermodynamic equilibrium, thermodynamic disequilibrium, and reaction kinetics. The five supporting data files contain both standard state and activity coefficient-related data. Three support the use of the Davies or B-dot equations for the activity coefficients; the other two support the use of Pitzer`s equations. The temperature range of the thermodynamic data on the data files varies from 25{degree}C only to 0--300{degree}C. EQPT takes a formatted data file (a data0 file) and writes an unformatted near-equivalent called a datal file, which is actually the form read by EQ3NR and EQ6. EQ3NR is useful for analyzing groundwater chemistry data, calculating solubility limits, and determining whether certain reactions are in states of partial equilibrium or disequilibrium. It is also required to initialize an EQ6 calculation. EQ6 models the consequences of reacting an aqueous solution with a set of reactants which react irreversibly. It can also model fluid mixing and the consequences of changes in temperature. This code operates both in a pure reaction progress frame and in a time frame.

STS-26 Commander Hauck in fixed based (FB) shuttle mission simulator (SMS)

Science.gov (United States)

1988-01-01

STS-26 Discovery, Orbiter Vehicle (OV) 103, Commander Frederick H. Hauck, wearing comunications kit assembly headset and seated in the commanders seat on forward flight deck, looks over his shoulder toward the aft flight deck. A flight data file (FDF) notebook rests on his lap. The STS-26 crew is training in the fixed base (FB) shuttle mission simulator (SMS) located in JSC Mission Simulation and Training Facility Bldg 5.

Electron-impact-ionization dynamics of S F6

Science.gov (United States)

Bull, James N.; Lee, Jason W. L.; Vallance, Claire

2017-10-01

A detailed understanding of the dissociative electron ionization dynamics of S F6 is important in the modeling and tuning of dry-etching plasmas used in the semiconductor manufacture industry. This paper reports a crossed-beam electron ionization velocity-map imaging study on the dissociative ionization of cold S F6 molecules, providing complete, unbiased kinetic energy distributions for all significant product ions. Analysis of these distributions suggests that fragmentation following single ionization proceeds via formation of S F5 + or S F3 + ions that then dissociate in a statistical manner through loss of F atoms or F2, until most internal energy has been liberated. Similarly, formation of stable dications is consistent with initial formation of S F4 2 + ions, which then dissociate on a longer time scale. These data allow a comparison between electron ionization and photoionization dynamics, revealing similar dynamical behavior. In parallel with the ion kinetic energy distributions, the velocity-map imaging approach provides a set of partial ionization cross sections for all detected ionic fragments over an electron energy range of 50-100 eV, providing partial cross sections for S2 +, and enables the cross sections for S F4 2 + from S F+ to be resolved.

No-carrier-added (NCA) synthesis of 6-[{sup 18}F]fluoro-L-DOPA using 3,5,6,7,8,8a-hexahydro-7,7,8a-trimethyl-[6S-(6{alpha}, 8{alpha}, 8{alpha}{beta})]-6,8-methano-2H-1,4-benzoxazin-2-one

Energy Technology Data Exchange (ETDEWEB)

Horti, A. [Yale Univ., New Haven, CT (United States). School of Medicine]|[Yale Univ., West Haven, CT (United States). PET Center; Redmond, D.E. Jr. [Yale Univ., New Haven, CT (United States). School of Medicine; Soufer, R. [Yale Univ., West Haven, CT (United States). PET Center

1995-12-31

3,5,6,7,8,8a-Hexahydro-7,7,8a-trimethyl-[6S-(6{alpha},8{alpha} , 8{alpha}{beta})]-6,8-methano-2H-1,4-benzoxazino-2-one (2) was investigated as chiral auxiliary for asymmetric NCA nucleophilic synthesis of 6-[{sup 18}F]Fluoro-L-DOPA. Direct condensation of 3,4-dimethoxy-2-[{sup 18}F]fluorobenzaldehyde (1a) or 6-[{sup 18}F]fluoro-piperonal (1b) in the presence of NaH with 2 gave the corresponding [{sup 18}F]-3-[(2-fluorophenyl)methylene]-3,5,6,7,8,8a-hexahydro-7,7,8 a-trimethyl-[6S-(3Z,3{alpha},6{alpha},8{alpha},8{alpha}{beta})]-6, 8-methano-2H-1,4-benzoxazin-2-one derivative 3a or 3b as a single stereoisomer. L-Selectride promoted hydrogenation of the olefinic double bond of these derivatives, in presence of tertbutyl alcohol, afforded the corresponding [{sup 18}F]-3-[(2-fluorophenyl) methyl]-3,5,6,7,8,8a-hexahydro-7,7,8a-trimethyl-[3S-(3{alpha}, 6{alpha}, 8{alpha}8{alpha}{beta})]-6,8-methano-2H-1,4-benzoxazin-2-one derivatives (4a,b) without affecting the orientation of diasterofacial discrimination. Deprotection of the derivatives 4a,b yielded 6-[{sup 18}F]fluoro-L-DOPA (e.e. >90%, 3% radiochemical yield (EOB), total synthesis time 125 min, specific activity >2000 mCi/{mu}mol). Direct deprotection/reduction of the compounds 3a,b provides the enantiomeric mixture of 6-[{sup 18}F]fluoro-D,L-DOPA (10-12% radiochemical yield) and, after chiral separation, 6-[{sup 18}F]fluoro-L-DOPA (e.e. 98%, 4-5% radiochemical yield). (author).

TOR and S6K1 promote translation reinitiation of uORF-containing mRNAs via phosphorylation of eIF3h.

Science.gov (United States)

Schepetilnikov, Mikhail; Dimitrova, Maria; Mancera-Martínez, Eder; Geldreich, Angèle; Keller, Mario; Ryabova, Lyubov A

2013-04-17

Mammalian target-of-rapamycin (mTOR) triggers S6 kinase (S6K) activation to phosphorylate targets linked to translation in response to energy, nutrients, and hormones. Pathways of TOR activation in plants remain unknown. Here, we uncover the role of the phytohormone auxin in TOR signalling activation and reinitiation after upstream open reading frame (uORF) translation, which in plants is dependent on translation initiation factor eIF3h. We show that auxin triggers TOR activation followed by S6K1 phosphorylation at T449 and efficient loading of uORF-mRNAs onto polysomes in a manner sensitive to the TOR inhibitor Torin-1. Torin-1 mediates recruitment of inactive S6K1 to polysomes, while auxin triggers S6K1 dissociation and recruitment of activated TOR instead. A putative target of TOR/S6K1-eIF3h-is phosphorylated and detected in polysomes in response to auxin. In TOR-deficient plants, polysomes were prebound by inactive S6K1, and loading of uORF-mRNAs and eIF3h was impaired. Transient expression of eIF3h-S178D in plant protoplasts specifically upregulates uORF-mRNA translation. We propose that TOR functions in polysomes to maintain the active S6K1 (and thus eIF3h) phosphorylation status that is critical for translation reinitiation.

The effect of short message system (SMS) reminder on adherence to a healthy diet, medication, and cessation of smoking among adult patients with cardiovascular diseases.

Science.gov (United States)

Akhu-Zaheya, Laila M; Shiyab, Wa'ed Y

2017-02-01

Cardiovascular Disease is the leading cause of death worldwide. Non-adherence to a recommended regimen among patients with Cardiovascular Diseases represents a significant problem which could lead to an increase in Cardiovascular Diseases. This study aimed to assess the effects of Short Message System (SMS) reminders on adherence to a healthy diet, medication, and cessation of smoking among adult patients with Cardiovascular Diseases. Randomized controlled trial design with three groups was used for this study. A non-probability convenient sample of 160 patients was recruited in this study. The participants were assigned randomly to an experimental group (received SMS regarding adherence to a healthy diet, medication, and smoking cessation), placebo group (received general messages) and control group (routine care). Morisky 8-Item Medication Adherence Scale (MMAS), Mediterranean Diet Adherence Screener (MEDAS), and Readiness to Quit Ladder, were used to assess patients' adherence to medication, adherence to Mediterranean diet, and smoking cessation, respectively. The outcomes were assessed at the beginning of the study and three months later, following completion of the intervention. One way ANONVA was used to assess the study hypothesis. Significant differences between study groups found in terms of adherence to medication (p=.001) and adherence to a healthy diet (p=.000); however, no significant difference was found between groups, in terms of intention to quit smoking, and/or the number of cigarettes smoked (p= .327), (p=.34), respectively. It is documented that SMS is effective in improving adherence to a healthy diet and medication. SMS could be a promising solution for management of different chronic diseases. It is recommended to apply Short Message System (SMS) via cellphone services to improve patient's adherence to a healthy diet and medication. However, further research is needed to support the effectiveness of SMS. Copyright © 2016 Elsevier Ireland

EQPT, a data file preprocessor for the EQ3/6 software package: User`s guide and related documentation (Version 7.0); Part 2

Energy Technology Data Exchange (ETDEWEB)

Daveler, S.A.; Wolery, T.J.

1992-12-17

EQPT is a data file preprocessor for the EQ3/6 software package. EQ3/6 currently contains five primary data files, called datao files. These files comprise alternative data sets. These data files contain both standard state and activity coefficient-related data. Three (com, sup, and nea) support the use of the Davies or B-dot equations for the activity coefficients; the other two (hmw and pit) support the use of Pitzer`s (1973, 1975) equations. The temperature range of the thermodynamic data on these data files varies from 25{degrees}C only to 0-300{degrees}C. The principal modeling codes in EQ3/6, EQ3NR and EQ6, do not read a data0 file, however. Instead, these codes read an unformatted equivalent called a data1 file. EQPT writes a datal file, using the corresponding data0 file as input. In processing a data0 file, EQPT checks the data for common errors, such as unbalanced reactions. It also conducts two kinds of data transformation. Interpolating polynomials are fit to data which are input on temperature adds. The coefficients of these polynomials are then written on the datal file in place of the original temperature grids. A second transformation pertains only to data files tied to Pitzer`s equations. The commonly reported observable Pitzer coefficient parameters are mapped into a set of primitive parameters by means of a set of conventional relations. These primitive form parameters are then written onto the datal file in place of their observable counterparts. Usage of the primitive form parameters makes it easier to evaluate Pitzer`s equations in EQ3NR and EQ6. EQPT and the other codes in the EQ3/6 package are written in FORTRAN 77 and have been developed to run under the UNIX operating system on computers ranging from workstations to supercomputers.

(2aR*,5S*,6aS*,8aS*,E-Ethyl 5-hydroxy-7,7,8a-trimethyl-8-oxo-2,2a,6,6a,7,8,8a,8b-octahydro-1H-pentaleno[1,6-bc]oxepine-4-carboxylate

Directory of Open Access Journals (Sweden)

Goverdhan Mehta

2012-12-01

Full Text Available The title compound, C17H24O5, featuring a 2-carbethoxy-3-oxepanone unit in its intramolecularly O—H...O hydrogen-bonded enol form, was obtained via [(CF3CO22Rh]2-catalysed intramolecular O—H bond insertion in the α-diazo-ω-hydroxy-β-ketoester, ethyl 4-[(1S,3aS,6R,6aS-6-hydroxy-2,2,3a-trimethyl-3-oxo-octahydropentalen-1-yl]-2-diazo-3-oxobutanoate. The seven-membered oxacyclic ring, thus constructed on a cis-fused diquinane platform, was found to adopt a distorted boat–sofa conformation.

STS-44 Atlantis, OV-104, Pilot Henricks in FB-SMS training at JSC

Science.gov (United States)

1991-01-01

STS-44 Atlantis, Orbiter Vehicle (OV) 104, Pilot Terence T. Henricks, seated at the pilots station on the forward flight deck, reviews checklists before a flight simulation in the Fixed Base (FB) Shuttle Mission Simulator (SMS) located in JSC's Mission Simulation and Training Facility Bldg 5. Surrounding Henricks are the seat back, the overhead panels, forward panels, and forward windows.

Solubility of NaNd(CO3)2.6H2O(c) in concentrated Na2CO3 and NaHCO3 solutions

International Nuclear Information System (INIS)

Rao, L.; Rai, D.; Felmy, A.R.; Fulton, R.W.; Novak, C.F.

1996-01-01

NaNd(CO 3 ) 2 x 6 H 2 O(c) was identified to be the final equilibrium solid phase in suspensions containing concentrated sodium carbonate (0.1 to 2.0 M) and sodium bicarbonate (0.1 to 1.0 M), with either NaNd(CO 3 ) 2 x 6 H 2 O(c) or Nd 2 (CO 3 ) 3 x xH 2 O(s) as initial solids. A thermodynamic model, based on Pitzer's specific into-interaction approach, was developed to interpret the solubility of NaNd(CO 3 ) 2 x 6 H 2 O(c) as functions of sodium carbonate and sodium bicarbonate concentrations. In this model, the solubility data of NaNd(CO 3 ) 2 x 6 H 2 O(c) were explained by assuming the formation of NdCO 3 + , Nd(CO 3 ) 2 - and Nd(CO 3 ) 3 3- species and invoking the specific ion interactions between Na + and Nd(CO 3 ) 3 3- . Ion interaction parameters for Na + -Nd(CO 3 ) 3 3- were developed to fit the solubility data. Based on the model calculations, Nd(CO 3 ) 3 3- was the predominant aqueous neodymium species in 0.1 to 2 M sodium carbonate and 0.1 to 1 M sodium bicarbonate solutions. The logarithm of the NaNd(CO 3 ) 2 x 6 H 2 O solubility product (NaNd(CO 3 ) 2 x 6 H 2 O(c)=Na + +Nd 3+ +2 CO 3 2- +6 H 2 O) was calculated to be -21.39. This model also provided satisfactory interpretation of the solubility data of the analogous Am(III) system in less concentrated carbonate and bicarbonate solutions. (orig.)

Uniqueness of the Fock representation of the Gowdy S1 x S2 and S3 models

International Nuclear Information System (INIS)

Cortez, Jeronimo; Marugan, Guillermo A Mena; Velhinho, Jose M

2008-01-01

After a suitable gauge fixing, the local gravitational degrees of freedom of the Gowdy S 1 x S 2 and S 3 cosmologies are encoded in an axisymmetric field on the sphere S 2 . Recently, it has been shown that a standard field parametrization of these reduced models admits no Fock quantization with a unitary dynamics. This lack of unitarity is surpassed by a convenient redefinition of the field and the choice of an adequate complex structure. The result is a Fock quantization where both the dynamics and the SO(3)-symmetries of the field equations are unitarily implemented. The present work proves that this Fock representation is in fact unique inasmuch as, up to equivalence, there exists no other possible choice of SO(3)-invariant complex structure leading to a unitary implementation of the time evolution

Aplikasi Short Message Service (SMS dan Email Sebagai Media Komunikasi Data dalam Sistem Pemantauan Suhu

Directory of Open Access Journals (Sweden)

Andi Adriansyah

2011-06-01

Full Text Available      Sistem pemantauan suhu secara langsung dengan mencatat setiap perubahan suhu secara manual, terlebih pada kondisi suhu yang ekstrim, memiliki resiko yang dapat berakibat fatal. Oleh karena itu dibutuhkan sebuah sistem yang dapat melakukannya secara otomatis. Penelitian ini bertujuan merancang sebuah sistem mandiri yang dapat melakukan pemantauan dan pencatatan perubahan suhu secara near real time (NRT dan mengirimkan laporan secara otomatis melalui email dan SMS. Sistem terdiri dari Sensor suhu LM35 yang berfungsi merubah besaran fisis suhu ke besaran listrik tegangan, Microcontroller Atmega8535 yang memegang peranan untuk mengkonversi tegangan keluaran LM35 kedalam bentuk digital, serta mengirimkan data hasil konversi melalui komunikasi serial ke computer. Program Java yang dijalankan di computer berfungsi memproses data yang dikirim mikrokontroler ATmega8535, menyimpannya ke basis data MySQL, menampilkannya dalam bentuk tabel dan grafik, dan mengirimkan laporan melalui email dan SMS bila data suhu yang diterima melebihi ambang batas yang telah ditentukan.

HerMES: The rest-frame UV emission and a lensing model for the z = 6.34 luminous dusty starburst galaxy HFLS3

International Nuclear Information System (INIS)

Cooray, Asantha; Calanog, Jae; Casey, C. M.; Ma, Brian; Osage, W. A.; Wardlow, Julie L.; Bock, J.; Bridge, C.; Burgarella, D.; Bussmann, R. S.; Clements, D.; Conley, A.; Farrah, D.; Fu, H.; Gavazzi, R.; Ivison, R. J.; La Porte, N.; Lo Faro, B.; Magdis, G.; Oliver, S. J.

2014-01-01

We discuss the rest-frame ultraviolet emission from the starbursting galaxy HFLS3 at a redshift of 6.34. The galaxy was discovered in Herschel/SPIRE data due to its red color in the submillimeter wavelengths from 250 to 500 μm. Keck/NIRC2 K s -band adaptive optics imaging data showed two potential near-IR counterparts near HFLS3. Previously, the northern galaxy was taken to be in the foreground at z = 2.1, while the southern galaxy was assumed to be HFLS3's near-IR counterpart. The recently acquired Hubble/WFC3 and Advanced Camera for Surveys (ACS) imaging data show conclusively that both optically bright galaxies are in the foreground at z < 6. A new lensing model based on the Hubble imaging data and the millimeter-wave continuum emission yields a magnification factor of 2.2 ± 0.3, with a 95% confidence upper limit on the magnification of 3.5. When corrected for lensing, the instantaneous star formation rate is 1320 M ☉ yr –1 , with the 95% confidence lower limit around 830 M ☉ yr –1 . The dust and stellar masses of HFLS3 from the same spectral energy distribution (SED) models are at the level of 3 × 10 8 M ☉ and ∼5 × 10 10 M ☉ , respectively, with large systematic uncertainties on assumptions related to the SED model. With Hubble/WFC3 images, we also find diffuse near-IR emission about 0.5 arcsec (∼3 kpc) to the southwest of HFLS3 that remains undetected in the ACS imaging data. The emission has a photometric redshift consistent with either z ∼ 6 or a dusty galaxy template at z ∼ 2.

Mutagenic and Cytotoxic Properties of 6-Thioguanine, S6-Methylthioguanine, and Guanine-S6-sulfonic Acid*S⃞

OpenAIRE

Yuan, Bifeng; Wang, Yinsheng

2008-01-01

Thiopurine drugs, including 6-thioguanine (SG), 6-mercaptopurine, and azathioprine, are widely employed anticancer agents and immunosuppressants. The formation of SG nucleotides from the thiopurine prodrugs and their subsequent incorporation into nucleic acids are important for the drugs to exert their cytotoxic effects. SG in DNA can be methylated by S-adenosyl-l-methionine to give S6-methylthioguanine (S6mG) and oxidized by UVA light to render guanine-S6-sulfonic acid ...

Aislamiento, identificación y daños asociados al síndrome de la muerte súbita en el cultivo de soja en Argentina

OpenAIRE

Scandiani, María Mercedes; Carmona, Marcelo Aníbal; Luque, Alicia Graciela; Matos, Kedma da Silva; Lenzi, Lisandro; Formento, Ángela Norma; Martinez, Cristina Valeria; Ferri, Mónica Raquel; Lo Piccolo, Melina; Tartabini, Mirta; Alvarez, Diego; Sautua, Francisco

2012-01-01

Los objetivos de este trabajo fueron aislar e identificar los agentes causales del síndrome de la muerte súbita (SMS) en muestras provenientes de diferentes localidades de Argentina, y cuantificar la incidencia de la enfermedad y los daños causados a campo en el rendimiento. Se analizaron 215 raíces provenientes de plantas con síntoma foliares típicos de SMS para el aislamiento e identificación de los agentes causales. Para realizar las pruebas de patogenicidad se efectuaron dos bioensayos en...

Euroopa Parlamendi ja Nõukogu uue direktiiviga 2008/0196 (COD) tarbija õiguste kohta kaasnevad muudatused SMS-laenu lepingute kehtivas regulatsioonis Eestis : [bakalaureusetöö] / Marite Privoi ; Tartu Ülikool, õigusteaduskond ; juhendaja: Mari

Index Scriptorium Estoniae

Privoi, Marite

2010-01-01

SMS-laenu lepingu olemusest ja sellega kaasnevatest tarbijakaitselistest probleemidest Eestis, direktiivi 2008/0196 (COD) kohast Euroopa Ühenduse tarbijakaitse õiguse kontekstis, direktiiviga kaasnevatest muudatustest SMS-laenu lepingute suhtes

STS-31 Pilot Bolden with beverages on the FB-SMS middeck during JSC training

Science.gov (United States)

1988-01-01

STS-31 Pilot Charles F. Bolden holds three beverage containers while in front of the galley on the middeck of the fixed based (FB) shuttle mission simulator (SMS) during a training simulation at JSC's Mission Simulation and Training Facility Bldg 5. From the middeck, Bolden, wearing lightweight headset, simulates a communications link with ground controllers and fellow crewmembers.

Field Distribution of Transcranial Static Magnetic Stimulation in Realistic Human Head Model.

Science.gov (United States)

Tharayil, Joseph J; Goetz, Stefan M; Bernabei, John M; Peterchev, Angel V

2017-10-10

The objective of this work was to characterize the magnetic field (B-field) that arises in a human brain model from the application of transcranial static magnetic field stimulation (tSMS). The spatial distribution of the B-field magnitude and gradient of a cylindrical, 5.08 cm × 2.54 cm NdFeB magnet were simulated in air and in a human head model using the finite element method and calibrated with measurements in air. The B-field was simulated for magnet placements over prefrontal, motor, sensory, and visual cortex targets. The impact of magnetic susceptibility of head tissues on the B-field was quantified. Peak B-field magnitude and gradient respectively ranged from 179-245 mT and from 13.3-19.0 T/m across the cortical targets. B-field magnitude, focality, and gradient decreased with magnet-cortex distance. The variation in B-field strength and gradient across the anatomical targets largely arose from the magnet-cortex distance. Head magnetic susceptibilities had negligible impact on the B-field characteristics. The half-maximum focality of the tSMS B-field ranged from 7-12 cm 3 . This is the first presentation and characterization of the three-dimensional (3D) spatial distribution of the B-field generated in a human brain model by tSMS. These data can provide quantitative dosing guidance for tSMS applications across various cortical targets and subjects. The finding that the B-field gradient is high near the magnet edges should be considered in studies where neural tissue is placed close to the magnet. The observation that susceptibility has negligible effects confirms assumptions in the literature. © 2017 International Neuromodulation Society.

A model for short message service advertising avoidance determinants – an Iranian experience

OpenAIRE

Shahriar AZIZI

2013-01-01

Short Message Service (SMS) advertising is a growing phenomenon in the Iranian marketing industry. Many Iranian companies are intensively interested in SMS advertising for its low cost and comprehensive coverage. The vital challenge in using SMS as an advertising medium is mobile avoidance. In this research, a conceptual model containing six hypotheses was developed and tested. Using 211 self-reporting questionnaires and structural equation modeling (SEM), this study found that self-esteem an...

Directed Evolution of Carbonyl Reductase from Rhodosporidium toruloides and Its Application in Stereoselective Synthesis of tert-Butyl (3R,5S)-6-Chloro-3,5-dihydroxyhexanoate.

Science.gov (United States)

Liu, Zhi-Qiang; Wu, Lin; Zhang, Xiao-Jian; Xue, Ya-Ping; Zheng, Yu-Guo

2017-05-10

tert-Butyl (3R,5S)-6-chloro-3,5-dihydroxyhexanoate ((3R,5S)-CDHH) is a key intermediate of atorvastatin and rosuvastatin synthesis. Carbonyl reductase RtSCR9 from Rhodosporidium toruloides exhibited excellent activity toward tert-butyl (S)-6-chloro-5-hydroxy-3-oxohexanoate ((S)-CHOH). For the activity of RtSCR9 to be improved, random mutagenesis and site-saturation mutagenesis were performed. Three positive mutants were obtained (mut-Gln95Asp, mut-Ile144Lys, and mut-Phe156Gln). These mutants exhibited 1.94-, 3.03-, and 1.61-fold and 1.93-, 3.15-, and 1.97-fold improvement in the specific activity and k cat /K m , respectively. Asymmetric reduction of (S)-CHOH by mut-Ile144Lys coupled with glucose dehydrogenase was conducted. The yield and enantiomeric excess of (3R,5S)-CDHH reached 98 and 99%, respectively, after 8 h bioconversion in a single batch reaction with 1 M (S)-CHOH, and the space-time yield reached 542.83 mmol L -1 h -1 g -1 wet cell weight. This study presents a new carbonyl reductase for efficient synthesis of (3R,5S)-CDHH.

Metal ion displacements in noncentrosymmetric chalcogenides La{sub 3}Ga{sub 1.67}S{sub 7}, La{sub 3}Ag{sub 0.6}GaCh{sub 7} (Ch=S, Se), and La{sub 3}MGaSe{sub 7} (M=Zn, Cd)

Energy Technology Data Exchange (ETDEWEB)

Iyer, Abishek K. [Department of Chemistry, University of Alberta, Edmonton, Alberta, Canada T6G2G2 (Canada); Yin, Wenlong [Department of Chemistry, University of Alberta, Edmonton, Alberta, Canada T6G2G2 (Canada); Institute of Chemical Materials, China Academy of Engineering Physics, Mianyang 621900 (China); Rudyk, Brent W. [Department of Chemistry, University of Alberta, Edmonton, Alberta, Canada T6G2G2 (Canada); Lin, Xinsong [Department of Chemistry, University of Alberta, Edmonton, Alberta, Canada T6G2G2 (Canada); Centre for Oil Sands Sustainability, Northern Alberta Institute of Technology, Edmonton, Alberta, Canada T6N1E5 (Canada); Nilges, Tom [Department of Chemistry, Technical University of Munich, 85748 Garching b. München (Germany); Mar, Arthur, E-mail: arthur.mar@ualberta.ca [Department of Chemistry, University of Alberta, Edmonton, Alberta, Canada T6G2G2 (Canada)

2016-11-15

The quaternary Ga-containing chalcogenides La{sub 3}Ag{sub 0.6}GaS{sub 7}, La{sub 3}Ag{sub 0.6}GaSe{sub 7}, La{sub 3}ZnGaSe{sub 7}, and La{sub 3}CdGaSe{sub 7}, as well as the related ternary chalcogenide La{sub 3}Ga{sub 1.67}S{sub 7}, were prepared by reactions of the elements at 950 °C. They adopt noncentrosymmetric hexagonal structures (space group P6{sub 3}, Z=2) with cell parameters (a=10.2 Å, c=6.1 Å for the sulfides; a=10.6 Å, c=6.4 Å for the selenides) that are largely controlled by the geometrical requirements of one-dimensional stacks of Ga-centered tetrahedra separated by the La atoms. Among these compounds, which share the common formulation La{sub 3}M{sub 1–x}GaCh{sub 7} (M=Ga, Ag, Zn, Cd; Ch=S, Se), the M atoms occupy sites within a stacking of trigonal antiprisms formed by Ch atoms. The location of the M site varies between extremes with trigonal antiprismatic (CN6) and trigonal planar (CN3) geometry. Partial occupation of these sites and intermediate ones accounts for the considerable versatility of these structures and the occurrence of large metal displacement parameters. The site occupations can be understood in a simple way as being driven by the need to satisfy appropriate bond valence sums for both the M and Ch atoms. Band structure calculations rationalize the substoichiometry observed in the Ag-containing compounds (La{sub 3}Ag{sub 0.6}GaS{sub 7}, La{sub 3}Ag{sub 0.6}GaSe{sub 7}) as a response to overbonding. X-ray photoelectron spectroscopy supports the presence of monovalent Ag atoms in these compounds, which are not charge-balanced. - Graphical abstract: Partial occupation of metal atoms in multiple sites accounts for versatility in Ga-containing chalcogenides La{sub 3}M{sub 1–x}GaCh{sub 7} with noncentrosymmetric hexagonal structures. - Highlights: • La{sub 3}M{sub 1–x}GaCh{sub 7} (M =Ga, Ag, Zn, Cd; Ch =S, Se) adopt related hexagonal structures. • Large displacements of M atoms originate from partial occupation of multiple

IL2-dependent phosphorylation of 40S ribosomal protein S6 is controlled by PI-3K/mTOR signalling in CTLL2 cells

Czech Academy of Sciences Publication Activity Database

Tuháčková, Zdena; Šloncová, Eva; Vojtěchová, Martina; Sovová, Vlasta

2004-01-01

Roč. 13, č. 4 (2004), s. 601-605 ISSN 1107-3756 R&D Projects: GA ČR GA301/00/0269 Institutional research plan: CEZ:AV0Z5052915 Keywords : MTOR /PI3-K signalling, p70 S 6 kinase, interleukin Subject RIV: CE - Biochemistry Impact factor: 3.190, year: 2004

Optical properties of GaS:Ho3+ and GaS:Tm3+ single crystals

International Nuclear Information System (INIS)

Jin, Moon-Seog; Kim, Chang-Dae; Kim, Wha-Tek

2004-01-01

GaS:Ho 3+ and GaS:Tm 3+ single crystals were grown by using the chemical transport reaction method. We measured the optical absorption, the infra-red absorption, and the photoluminescence spectra of the single crystals. The direct and the indirect energy band gaps of the single crystals at 13 K were identified. Infra-red absorption peaks at 6 K appeared in the single crystals. Broad emission bands at 6 K were observed at 464 nm and 580 nm for GaS:Ho 3+ and 462 nm and 581 nm for GaS:Tm 3+ . These broad emission bands were identified as originating from donor-acceptor pair recombinations. Sharp emission peak groups were observed near 435 nm, 495 nm, and 660 nm for GaS:Ho 3+ and near 672 nm for GaS:Tm 3+ . These sharp emission peak groups were identified as being due to the electron transitions between the energy levels of Ho 3+ and Tm 3+ . Especially, white photoluminescence was obtained in the GaS:Ho 3+ single crystal.

STS-46 crewmembers participate in Fixed Base (FB) SMS training at JSC

Science.gov (United States)

1992-01-01

STS-46 Atlantis, Orbiter Vehicle (OV) 104, Pilot Andrew M. Allen hands Mission Specialist (MS) and Payload Commander (PLC) Jeffrey A. Hoffman checklists from middeck locker MF43E during training session in JSC's fixed base (FB) shuttle mission simulator (SMS) located in Mission Simulation and Training Facility Bldg 5. European Space Agency (ESA) MS Claude Nicollier outfitted with communications kit assembly headset (HDST) and equipment looks beyond Hoffman to the opposite side of the middeck.

Hyperfine structure and isotope shift analysis of singly ionized titanium

Science.gov (United States)

Bouazza, Safa

2013-04-01

The even-parity low configuration system of Ti II has been considered on the basis of the experimental data found in the literature, and its fine structure has been reanalyzed by simultaneous parameterization of one- and two-body interactions for the model space (3d + 4s)3. Furthermore, the main one-electron hyperfine structure parameters for these configurations have been evaluated. For instance, for 3d24s1, a_{3{\\rm{d}}}^{01} = - {\\rm{63}}.{\\rm{2}}\\left( {{\\rm{3}}.{\\rm{1}}} \\right)\\,{\\rm{MHz}} and a_{4{\\rm{s}}}^{10} = - {\\rm{984}}.{\\rm{1}}\\left( {{\\rm{7}}.{\\rm{1}}} \\right)\\,{\\rm{MHz}} . Field shifts (FS) and specific mass shifts (SMS) of the main Ti II configurations are deduced by means of ab initio estimates combined with a small quantity of experimental isotope shift data available in the literature: FS(3d3) = -63.3 MHz, FS(3d24p1) = -49.7 MHz, FS(3d14s2) = 98.2 MHz, FS(4s24P1) = 163.4 MHz and SMS(3d3) = 1453.3 MHz, SMS(3d14s2) = -2179.7 MHz, …, referred to 3d24s1 for the pair Ti46-Ti48.

39 CFR 6.3 - Notice of meetings.

Science.gov (United States)

2010-07-01

... 39 Postal Service 1 2010-07-01 2010-07-01 false Notice of meetings. 6.3 Section 6.3 Postal Service UNITED STATES POSTAL SERVICE THE BOARD OF GOVERNORS OF THE U.S. POSTAL SERVICE MEETINGS (ARTICLE VI) § 6.3 Notice of meetings. The Chairman or the members of the Board may give the notice required under...

The Effect of Feedback by SMS-text messages and email on Household Electricity Consumption: Experimental Evidence

DEFF Research Database (Denmark)

Larsen, Anders

2010-01-01

This paper analyzes the effect of supplying online feedback by SMS-text messages and email about electricity consumption on the level of total household electricity consumption. An experiment was conducted in which 1,452 households were randomly allocated to three experimental groups and two...

Maturity Models in the Age of Digital Diversity

DEFF Research Database (Denmark)

Andersen, Kim Normann; Henriksen, Helle Zinner; Medaglia, Rony

2012-01-01

-government maturity model by Layne and Lee [1] included in the proposal of the Public Sector Process Rebuilding (PPR) model [2, 3]. The adoption and adaptation of Web 2.0 platforms and location-based services, and the parallel extension of conventional technologies as SMS and web-based self-services, challenge...

The ADaptation and Anticipation Model (ADAM) of sensorimotor synchronization

Science.gov (United States)

van der Steen, M. C. (Marieke); Keller, Peter E.

2013-01-01

A constantly changing environment requires precise yet flexible timing of movements. Sensorimotor synchronization (SMS)—the temporal coordination of an action with events in a predictable external rhythm—is a fundamental human skill that contributes to optimal sensory-motor control in daily life. A large body of research related to SMS has focused on adaptive error correction mechanisms that support the synchronization of periodic movements (e.g., finger taps) with events in regular pacing sequences. The results of recent studies additionally highlight the importance of anticipatory mechanisms that support temporal prediction in the context of SMS with sequences that contain tempo changes. To investigate the role of adaptation and anticipatory mechanisms in SMS we introduce ADAM: an ADaptation and Anticipation Model. ADAM combines reactive error correction processes (adaptation) with predictive temporal extrapolation processes (anticipation) inspired by the computational neuroscience concept of internal models. The combination of simulations and experimental manipulations based on ADAM creates a novel and promising approach for exploring adaptation and anticipation in SMS. The current paper describes the conceptual basis and architecture of ADAM. PMID:23772211

STS-26 crew trains in JSC fixed-based (FB) shuttle mission simulator (SMS)

Science.gov (United States)

1987-01-01

STS-26 Discovery, Orbiter Vehicle (OV) 103, crewmembers (left to right) Commander Frederick H. Hauck, Pilot Richard O. Covey, Mission Specialist (MS) George D. Nelson, MS David C. Hilmers, and MS John M. Lounge pose on the middeck in fixed-based (FB) shuttle mission simulator (SMS) located in JSC Mission Simulation and Training Facility Bldg 5. A simulation for their anticipated June 1988 flight began 10-20-87.

Lorentz Violation of the Photon Sector in Field Theory Models

Directory of Open Access Journals (Sweden)

Lingli Zhou

2014-01-01

Full Text Available We compare the Lorentz violation terms of the pure photon sector between two field theory models, namely, the minimal standard model extension (SME and the standard model supplement (SMS. From the requirement of the identity of the intersection for the two models, we find that the free photon sector of the SMS can be a subset of the photon sector of the minimal SME. We not only obtain some relations between the SME parameters but also get some constraints on the SMS parameters from the SME parameters. The CPT-odd coefficients (kAFα of the SME are predicted to be zero. There are 15 degrees of freedom in the Lorentz violation matrix Δαβ of free photons of the SMS related with the same number of degrees of freedom in the tensor coefficients (kFαβμν, which are independent from each other in the minimal SME but are interrelated in the intersection of the SMS and the minimal SME. With the related degrees of freedom, we obtain the conservative constraints (2σ on the elements of the photon Lorentz violation matrix. The detailed structure of the photon Lorentz violation matrix suggests some applications to the Lorentz violation experiments for photons.

Using Spent Mushroom Substrate as the Base for Organic-Mineral Micronutrient Fertilizer – Field Tests on Maize

Directory of Open Access Journals (Sweden)

Łukasz Tuhy

2015-07-01

Full Text Available Spent mushroom substrate (SMS is a noxious byproduct of the mushroom industry. The aim of this work was to convert SMS into organic-mineral micronutrient (Zn(II, Mn(II, and Cu(II fertilizer via biosorption and examine the effect of its application in field tests on maize compared to commercial reference micronutrient fertilizer. Crop yield and crop quality were assessed, and multielemental analysis of grains was conducted for the evaluation of the fertilization effect on maize grains and to assess bioavailability of nutrients from fertilizers. Grain yield for maize treated with micronutrients delivered with SMS was noticeably higher (11.5% than the untreated group and the NPK (nitrogen, phosphorus, potassium fertilizer treated only group (2.8%. Bioavailability (TF of micronutrients from SMS were comparable with reference micronutrient fertilizer (7% Zn, 4% Mn, and 2.3% Cu. The new product has the potential to be used as a micronutrient fertilizer. Satisfactory results of grain yield (6.4 Mg ha-1, high content of micronutrients (Zn 1.6%, Mn 1.2%, and Cu 1.8%, and macronutrients (P 1.0%, S 3.1%, Ca 8.2%, and K 0.2% were observed. The bioavailability suggests that enriched SMS could be a good alternative to fertilizers in the present market.

Aplikasi Pemantau Perangkat Jaringan Berbasis Web Menggunakan Protokol SNMP dan Notifikasi SMS

Directory of Open Access Journals (Sweden)

Shofa Taftazanie

2017-05-01

Full Text Available Device monitoring tool on a computer network is required by the administrator to perform management of the device. This research produces web applications using PHP that is capable of monitoring and collecting device information on the network. This app uses SNMP and syslog protocols to perform monitoring on the device. Device information will be collected on the monitor server and displayed in web-based applications. This app using crontab to be able to monitor every minute. This application can also send a warning message in the form of SMS and email to the administrator when an error occurs on the device so that handling is expected to be faster done. This web application can make it easier for administrators to monitor devices anywhere. Pemantauan perangkat pada suatu jaringan komputer sangat diperlukan oleh administrator untuk melakukan manajemen perangkat tersebut. Penelitian ini menghasilkan aplikasi web menggunakan PHP yang mampu melakukan pemantauan dan pengumpulan informasi perangkat di jaringan. Aplikasi ini menggunakan protokol SNMP dan syslog untuk melakukan pemantauan pada perangkat. Informasi perangkat akan dikumpulkan pada server monitor dan ditampilkan pada aplikasi berbasis web. Aplikasi menggunakan crontab agar dapat melakukan pemantauan setiap menit. Aplikasi juga dapat mengirimkan pesan peringatan berupa SMS dan email kepada administrator saat terjadi kesalahan pada perangkat server sehingga penanganan diharapkan dapat lebih cepat dilakukan. Aplikasi web ini dapat mempermudah administrator dalam memantau perangkat dimana saja.

STS-44 Atlantis, OV-104, MS Musgrave on FB-SMS middeck during JSC training

Science.gov (United States)

1991-01-01

STS-44 Atlantis, Orbiter Vehicle (OV) 104, Mission Specialist (MS) F. Story Musgrave, wearing lightweight headset (HDST), adjusts controls on communications module mounted on a middeck overhead panel. Musgrave is on the middeck of the Fixed Base (FB) Shuttle Mission Simulator (SMS) located in JSC's Mission Simulation and Training Facility Bldg 5. The STS-44 crewmembers are participating in a flight simulation.

STS-44 Atlantis, OV-104, crewmembers participate in JSC FB-SMS training

Science.gov (United States)

1991-01-01

STS-44 Atlantis, Orbiter Vehicle (OV) 104, Commander Frederick D. Gregory and Pilot Terence T. Henricks are stationed at their appointed positions on the forward flight deck of the Fixed Base (FB) Shuttle Mission Simulator (SMS) in JSC's Mission Simulation and Training Facility Bldg 5. Gregory (left) in the commanders seat and Henricks (right) in the pilots seat look back toward aft flight deck and the photographer. Seat backs appear in the foreground and forward flight deck control panels in the background.

Energy dependence of particle ratio fluctuations in central Pb+Pb collisions from $\\sqrt{s_{_{NN}}} =$~6.3 to 17.3 GeV

CERN Document Server

Alt, C; Baatar, B; Barna, D; Bartke, J; Betev, L; Bialkowska, H; Blume, C; Boimska, B; Botje, M; Bracinik, J; Bramm, R; Bunccic, P; Cerny, V; Christakoglou, P; Chvala, O; Cramer, J G; Csató, P; Dinkelaker, P; Eckardt, V; Flierl, D; Fodor, Z; Foka, P; Friese, V; Gál, J; Gazdzicki, M; Genchev, V; Georgopoulos, G; Gladysz, E; Grebieszkow, K; Hegyi, S; Höhne, C; Kadija, K; Karev, A; Kliemant, M; Kniege, S; Kolesnikov, V I; Kornas, E; Korus, R; Kowalski, M; Kraus, I; Kreps, M; Kresan, D; Van Leeuwen, M; Lévai, P; Litov, L; Lungwitz, B; Makariev, M; Malakhov, A I; Mateev, M; Melkumov, G L; Mischke, A; Mitrovski, M; Molnár, J; Mrówczynski, St; Nicolic, V; Pálla, G; Panagiotou, A D; Panayotov, D; Petridis, A; Pikna, M; Prindle, D; Pühlhofer, F; Renfordt, R; Roland, C; Roland, G; Rybczynski, M; Rybicki, A; Sandoval, A; Schmitz, N; Schuster, T; Seyboth, P; Siklér, F; Sitár, B; Skrzypczak, E; Stefanek, G; Stock, R; Ströbele, H; Susa, T; Szentpétery, I; Sziklai, J; Szymanski, P; Trubnikov, V; Varga, D; Vassiliou, M; Veres, G I; Vesztergombi, G; Vranic, D; Wetzler, A; Wlodarczyk, Z; Yoo, I K

2009-01-01

We present recent measurements of the energy dependence of event-by-event fluctuations in the K/pi and (p + \\bar{p})/pi multiplicity ratios in heavy ion collisions at the CERN SPS. The particle ratio fluctuations were obtained for central Pb+Pb collisions at five collision energies, \\sqrt{s_{_{NN}}}, between 6.3 and 17.3 GeV. After accounting for the effects of finite-number statistics and detector resolution, we extract the strength of non-statistical fluctuations at each energy. For the K/pi ratio, larger fluctuations than expected for independent particle production are found at all collision energies. The fluctuations in the (p + \\bar{p})/pi ratio are smaller than expectations from independent particle production, indicating correlated pion and proton production from resonance decays. For both ratios, the deviation from purely statistical fluctuations shows an increase towards lower collision energies. The results are compared to transport model calculations, which fail to describe the energy dependence o...

EQ3/6 geochemical modeling task plan for Nevada Nuclear Waste Storage Investigations (NNWSI)

Energy Technology Data Exchange (ETDEWEB)

Isherwood, D.; Wolery, T.

1984-04-10

This task plan outlines work needed to upgrade the EQ3/6 geochemical code and expand the supporting data bases to allow the Nevada Nuclear Waste Storage Investigations (NNWSI) to model chemical processes important to the storage of nuclear waste in a tuff repository in the unsaturated zone. The plan covers the fiscal years 1984 to 1988. The scope of work includes the development of sub-models in the EQ3/6 code package for studying the effects of sorption, precipitation kinetics, redox disequilibrium, and radiolysis on radionuclide speciation and solubility. The work also includes a glass/water interactions model and a geochemical flow model which will allow us to study waste form leaching and reactions involving the waste package. A special emphasis is placed on verification of new capabilities as they are developed and code documentation to meet NRC requirements. Data base expansion includes the addition of elements and associated aqueous species and solid phases that are specific to nuclear waste (e.g., actinides and fission products) and the upgrading and documentation of the thermodynamic data for other species of interest.

Continuously moving table MRI with sliding multislice for rectal cancer staging: Image quality and lesion detection

International Nuclear Information System (INIS)

Baumann, Tobias; Ludwig, Ute; Pache, Gregor; Fautz, Hans-Peter; Kotter, Elmar; Langer, Mathias; Schaefer, Oliver

2010-01-01

Purpose: To determine image quality and lesion detection of sliding multislice (SMS), a recently developed moving table MRI technique, in patients with rectal cancer. Materials and methods: Twenty-seven paired SMS (Avanto, Siemens Medical Solutions) and MDCT (Sensation 64, Siemens Medical Solutions) examinations of abdomen and pelvis were performed in patients with rectal cancer and compared for detection of liver, lymph node and bone metastases by two independent observers. A contrast-enhanced, fat saturated 2D gradient echo sequence (TE, 2.0 ms; TR, 102 ms; slice, 5 mm) was acquired with SMS and a standard contrast-enhanced protocol (100 ml 2.5 ml/s; slice, 5 mm) was used for abdominal MDCT. Standard of reference consisted of a consensus evaluation of SMS, MDCT, and all available follow-up examinations after a period of 6 months. Artifact burden and image quality of SMS was assessed in comparison to stationary gradient echo sequences obtained in an age-matched group of 27 patients. Results: Whereas SMS achieved a mean quality score of 3.65 (scale, 0-4) for the liver, representing very good diagnostic properties, strong breathing artifacts in the intestinal region were observed in 19 cases by both observers. The retroperitoneum still achieved a mean quality score of 3.52, although breathing artifacts were noted in 12 and 15 cases (observers 1 and 2, respectively). The sensitivities of SMS to detect hepatic metastases were 91.2% and 94.1% for both observers, respectively, compared to 98.5%/98.5% for MDCT. The sensitivities for lymph node metastases were 87.5%/81.3% for SMS compared to 78.1%/81.3% for MDCT. The sensitivities for bone metastases were 91.7%/100% for SMS compared to 8.3%/16.7% for MDCT. Conclusion: With slightly reduced image quality in the intestinal region, SMS exhibits equal detection of lymph node and liver metastases compared to MDCT. SMS MRI proved to be superior to MDCT in detection of bone metastases.

Identification of Viruses Present in Tissues Collected from Chickens with Hypoglycemia-Spiking Mortality Syndrome (H-SMS).

Science.gov (United States)

Tissues were collected, over a 10-year period, from broiler chickens diagnosed with severe H-SMS at the Georgia Poultry Lab, in Oakwood, GA. All samples were stored in tissue culture media, with antibiotics and 15% fetal bovine serum, in an ultra-cold freezer @ -80F. Specimens were homogenized,...

Implementation of CycleTel Family Advice: an SMS-based service to provide family planning and fertility awareness information in India.

Science.gov (United States)

Ashcroft, Nicki; Shelus, Victoria; Garg, Himanshu; McLarnon-Silk, Courtney; Jennings, Victoria H

2017-01-01

CycleTel Family Advice (CFA), an SMS-based service designed to improve knowledge of fertility and family planning (FP), was delivered to over 100,000 people in India from April to August 2015. The goal of CFA was to increase knowledge on a range of reproductive health topics, e.g., the menstrual cycle, fertility, and FP, and to increase positive perceptions and use of FP. This paper focuses on the best practices and operational challenges for providing an SMS service based on the implementation experience of CFA. The implementation process for CFA was well documented, specifically program design, commercial partnerships, formative research, design of messages, and recruitment of users. The impact of CFA on knowledge, attitudes, and behaviors was assessed through phone surveys before and after message delivery. Programmatic data and phone surveys resulted in several operational findings, particularly in the areas of user behavior, partnership management, and mHealth research. While there were improvements in knowledge, there were not significant changes in FP use and couple communication. The intervention yielded insights into designing an mHealth intervention as well as the opportunities and challenges of implementing a stand-alone SMS-based service with a broad audience. Lessons learned were that (I) SMS-based interventions, without other supporting systems, may not lead to high user engagement or behavior change; (II) partnerships with private sector technical platforms can help overcome the difficult problem of marketing and outreach, but they bring limitations to user interface and dependencies on a commercial structure; (III) collecting demographic data required to provide tailored content may be a barrier to user acquisition; and (IV) while phone surveys are useful for evaluation of mHealth interventions, reaching users is challenging and response rates are low.

Highly efficient enzymatic synthesis of tert-butyl (S)-6-chloro-5-hydroxy-3-oxohexanoate with a mutant alcohol dehydrogenase of Lactobacillus kefir.

Science.gov (United States)

He, Xiu-Juan; Chen, Shao-Yun; Wu, Jian-Ping; Yang, Li-Rong; Xu, Gang

2015-11-01

tert-Butyl (S)-6-chloro-5-hydroxy-3-oxohexanoate ((S)-CHOH) is a valuable chiral synthon, which is used for the synthesis of the cholesterol-lowering drugs atorvastatin and rosuvastatin. To date, only the alcohol dehydrogenases from Lactobacillus brevis (LbADH) and Lactobacillus kefir (LkADH) have demonstrated catalytic activity toward the asymmetric reduction of tert-butyl 6-chloro-3,5-dioxohexanoate (CDOH) to (S)-CHOH. Herein, a tetrad mutant of LkADH (LkTADH), A94T/F147L/L199H/A202L, was screened to be more efficient in this bioreduction process, exhibiting a 3.7- and 42-fold improvement in specific activity toward CDOH (1.27 U/mg) over LbADH (0.34 U/mg) and wild-type LkADH (0.03 U/mg), respectively. The molecular basis for the improved catalytic activity of LkTADH toward CDOH was investigated using homology modeling and docking analysis. Two major issues had a significant impact on the biocatalytic efficiency of this process, including (i) the poor aqueous stability of the substrate and (ii) partial substrate inhibition. A fed-batch strategy was successfully developed to address these issues and maintain a suitably low substrate concentration throughout the entire process. Several other parameters were also optimized, including the pH, temperature, NADP(+) concentration and cell loading. A final CDOH concentration of 427 mM (100 g/L) gave (S)-CHOH in 94 % yield and 99.5 % e.e. after a reaction time of 38 h with whole cells expressing LkTADH. The space-time yield and turnover number of NADP(+) in this process were 10.6 mmol/L/h and 16,060 mol/mol, respectively, which were the highest values ever reported. This new approach therefore represents a promising alternative for the efficient synthesis of (S)-CHOH.

STS-48 MS Buchli and MS Gemar on MB SMS middeck during JSC training session

Science.gov (United States)

1991-01-01

STS-48 Discovery, Orbiter Vehicle (OV) 103, Mission Specialist (MS) James F. Buchli (left) and MS Charles D. Gemar listen to instructions while on the middeck of JSC's Motion Based (MB) Shuttle Mission Simulator (SMS). Buchli and Gemar are reviewing inflight procedures during this preflight familiarization session held in the Mission Simulation and Training Facility Bldg 5.

Physical and transcript map of the region between D6S264 and D6S149 on chromosome 6q27, the minimal region of allele loss in sporadic epithelial ovarian cancer

DEFF Research Database (Denmark)

Liu, Ying; Emilion, Gracy; Mungall, Andrew J

2002-01-01

We have previously shown a high frequency of allele loss at D6S193 (62%) on chromosomal arm 6q27 in ovarian tumours and mapped the minimal region of allele loss between D6S297 and D6S264 (3 cM). We isolated and mapped a single non-chimaeric YAC (17IA12, 260-280 kb) containing D6S193 and D6S297...

Nitrogen Adsorption and Hydrogenation on a MoFe6S9 Complex

DEFF Research Database (Denmark)

Rod, Thomas Holm; Hammer, Bjørk; Nørskov, Jens Kehlet

1999-01-01

The enzyme nitrogenase catalyzes the biological nitrogen fixation where N-2 is reduced to NH3. Density functional calculations are presented of the bonding and hydrogenation of N-2 on a MoFe6S9 complex constructed to model aspects of the active site of nitrogenase. N-2 is found to bind end on to ...... on to one of the Fe atoms. A complete energy diagram for the addition of hydrogen to the MoFe6S9 complex with and without N-2 is given, and a mechanism for ammonia synthesis is proposed on this basis....

Crystal structure of the Hg4SiS6 and Hg4SiSe6 compounds

International Nuclear Information System (INIS)

Gulay, L.D.; Olekseyuk, I.D.; Parasyuk, O.V.

2002-01-01

The crystal structures of Hg 4 SiS 6 and Hg 4 SiSe 6 compounds were investigated using X-ray powder diffraction. These compounds crystallize in the monoclinic Cc space group with the lattice parameters a=1.23020(5), b=0.71031(4), c=1.22791(4) nm, β=109.721(3) deg. for Hg 4 SiS 6 and a=1.28110(4), b=0.74034(4), c=1.27471(1) nm, β=109.605(3) deg. for Hg 4 SiSe 6 . Atomic parameters were refined in the isotropic approximation (R I =0.0571 and R I =0.0555 for the Hg 4 SiS 6 and Hg 4 SiSe 6 , respectively)

Rancang Bangun Sistem Pemantauan dan Peringatan dini Parameter Lingkungan Mikro Budidaya Tanaman pada Rumah Tanaman Berbasis SMS (Short Message Service

Directory of Open Access Journals (Sweden)

Mohamad Solahudin

2006-12-01

Full Text Available SMS (Short Message Service is one of technology can be use alternative to develop greenhouse micro climate monitoring and alert system. This technology selected because of simplicity in information access and widely spread use as comunication tools. The purpose of this research is to develop greenhouse Micro Climate Monitoring and Alert System by combining SMS technology, Portable Weather Station and Mobile FBUS V 1.5. System test performance for variouse provider shows the result wihch vary. The results shows that this system can be applied as monitoring and alert system technology. The performance test shows thaht the average of time service from all communication providers is 24,45 second, with 2.65 lag time.

An effective 2-band eg model of sulfur hydride H3S for high-Tc superconductivity

Science.gov (United States)

Nishiguchi, Kazutaka; Teranishi, Shingo; Miyao, Satoaki; Matsushita, Goh; Kusakabe, Koichi

To understand high transition temperature (Tc) superconductivity in sulfur hydride H3S, we propose an effective 2-band model having the eg symmetry as the minimal model for H3S. Two eg orbitals centered on a sulfur S atom are chosen for the smallest representation of relevant bands with the van-Hove singularity around the Fermi levels except for the Γ-centered small hole pockets by the sulfur 3 p orbitals. By using the maximally localized Wannier functions, we derive the minimal effective model preserving the body-centered cubic (bcc) crystal symmetry of the H3S phase having the highest Tc ( 203 K under pressures) among the other polymorphs of H3S.

BPS spectrum on AdS{sub 3}×S{sup 3}×S{sup 3}×S{sup 1}

Energy Technology Data Exchange (ETDEWEB)

Eberhardt, Lorenz; Gaberdiel, Matthias R. [Institut für Theoretische Physik, ETH Zurich,CH-8093 Zürich (Switzerland); Gopakumar, Rajesh [International Centre for Theoretical Sciences-TIFR,Survey No. 151, Shivakote, Hesaraghatta Hobli,Bengaluru North, 560 089 (India); Li, Wei [Institute of Theoretical Physics, Chinese Academy of Science,100190 Beijing (China)

2017-03-23

The BPS spectrum of string theory on AdS{sub 3}×S{sup 3}×S{sup 3}×S{sup 1} is determined using a world-sheet description in terms of WZW models. It is found that the theory only has BPS states with j{sup +}=j{sup −} where j{sup ±} refer to the spins of the su(2) algebras of the large N=4 superconformal algebra. We then re-examine the BPS spectrum of the corresponding supergravity and find that, contrary to previous claims in the literature, also in supergravity only the states with j{sup +}=j{sup −} are BPS. This resolves a number of long-standing puzzles regarding the BPS spectrum of string theory and supergravity in this background.

Phase transition in Smsub(1-x)Gdsub(x)S and Smsub(1-x)Tmsub(x)S solid solutions under pressure

International Nuclear Information System (INIS)

Kaminskij, V.V.; Stepanov, N.N.; Romanova, M.V.

1985-01-01

Experiments are conducted on studying the effect of the n quantity on Psub(pt) (phase transition pressure) for SmS and systems of solid solutions Smsub(1-x)Gdsub(x)S and Smsub(1-x)Tmsub(x)S with conductivity electron concentrations approximately 10 19 -10 21 cm -3 corresponding to the semiconducting phase of these solutions. The investigated monocrystal samples have been prepared by the method of planar crystallization from the melt, have been chipped off over the cleavage planes [100], their characteristic sizes not exceeding 2 mm. Samples of the Smsub(1-x)Tmsub(x)S system were polycrystalline and they had characteristic dimensions of approximately 3mm. Concentration of conductivity electrons has been determined from measurements of the Hall constant. Hydrostatic compression of the samples has been exercised in a piston high-pressure chamber at T=300 K. The observed electric conductivity jump determined by the standard d.c. compensation technique was a criterion of the presence of the phase transition to the metal state. Dependences of Psub(pt) in SmS base solid solutions with approximately 10 19 -10 21 cm -3 concentration of conductivity electrons have similar tendency in behaviour: a certain increase in the phase transition pressure with n growth and then its drop at n approaching concentrations corresponding to compositions close to critical ones for the semiconductor-metal phase transition in any system of solid solutions. If the first mechanism prevails at small as then further on the second mechanism swelling by a power law with a high index plays the main role

Siemens Wind Power 3.6 MW wind turbines for large offshore wind farms

Energy Technology Data Exchange (ETDEWEB)

Akhmatov, Vladislav; Nygaard Nielsen, Joergen; Thisted, Jan; Groendahl, Erik; Egedal, Per; Noertoft Frydensbjerg, Michael; Jensen, Kim Hoej [Siemens Wind Power A/S, Brande (Denmark)

2008-07-01

Siemens Wind power A/S is the key player on the offshore wind power market. The Siemens Wind Power 3.6 MW variable-speed wind turbine is among the word's largest, most advanced and competitive wind turbines with a solid portfolio of large offshore wind farms. Transmission system operators and developers require dynamic wind turbine models for evaluation of fault-ride-through capability and investigations of power system stability. The even larger size of the on- and offshore wind farms has entailed that the grid impact of the voltage and frequency control capability of the wind farm can be appropriated modelled and evaluated. Siemens Wind Power has developed a dynamic model of the 3.6 MW variable-speed wind turbine with the fault-ride-through sequences and models of the voltage and frequency controllers to be applied for large offshore wind farms. The dynamic models have been implemented in the commercially available simulation tools such as DIgSILENT PowerFactory and Siemens PTI PSS/E and successfully validated from measurements. (orig.)

Growth and Characterization of Organic Based Marine Dye NLO Material: 7-Bromo-6-chloro-3-[3-[(2R, 3S)-3-hydroxy-2-piperidyl]-2-oxopropyl]-4(3H)-quinazolinone

OpenAIRE

M. Jayandran; V. Balasubramanian

2011-01-01

An organic marine dye compound (7-bromo-6-chloro-3-[3-[(2R, 3S)-3-hydroxy-2-piperidyl]-2-oxopropyl]-4(3H)-quinazolinone) was synthesized. The characteristics of this dye is soluble in water. The organic compound was made into a crystal by slow evaporation technique. The grown crystals were characterized by single crystal x-ray diffraction (XRD) analysis, FTIR studies and UV-visible transmittance studies and the NLO activity of the grown crystal has been checked by second harmonic generation (...

40 CFR 180.1281 - S-Abscisic Acid, (S)-5-(1-hydroxy-2,6,6-trimethyl-4-oxo-1-cyclohex-2-enyl)-3-methyl-penta-(2Z,4E...

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 23 2010-07-01 2010-07-01 false S-Abscisic Acid, (S)-5-(1-hydroxy-2,6... Exemptions From Tolerances § 180.1281 S-Abscisic Acid, (S)-5-(1-hydroxy-2,6,6-trimethyl-4-oxo-1-cyclohex-2... from the requirement of a tolerance is established for residues of S-Abscisic Acid in or on all food...

Historieportal 3.-6. - historie3-6.gyldendal.dk

DEFF Research Database (Denmark)

Poulsen, Jens Aage

Portal, der indeholder tekster, video, billeder, interaktive opgaver m.m. til undervisningen i historie i 3.-6. klasse......Portal, der indeholder tekster, video, billeder, interaktive opgaver m.m. til undervisningen i historie i 3.-6. klasse...

SU(6) quadrupole phonon model for even and odd nuclei and the SU(3) limit

Energy Technology Data Exchange (ETDEWEB)

Paar, V; Brant, S [Zagreb Univ. (Yugoslavia). Prirodoslovno Matematicki Fakultet; Canto, L F [Rio de Janeiro Univ. (Brazil). Inst. de Fisica; Leander, G [Lund Inst. of Tech. (Sweden). Dept. of Mathematical Physics; Oak Ridge National Lab., TN (USA)); Vouk, M [Zagreb Univ. (Yugoslavia). Computing Centre SRCE

1982-04-05

Analogous to the equivalence between the SU(6) quadrupole-phonon model (TQM) and the interacting boson model (IBM), the equivalence is pointed out for odd systems between the SU(6) particle quadrupole-phonon coupling model (PTQM) and the interacting boson-fermion model (IBFM). PTQM is formulated starting from the Dyson representation for the odd system. Different aspects of the SU(3) limit of TQM and PTQM are studied; the quadrupole-phonon block structure of rotational bands in even and odd nuclei and analytic expressions based on the coherent state; signature effects generated in PTQM; electromagnetic properties and correction factors for PTQM; overlaps of the PTQM analogs of Nilsson states with Coriolis-coupled Nilsson states and the relation to the rotational model representation.

Letter Report: Progress in developing EQ3/6 for modeling boiling processes

Energy Technology Data Exchange (ETDEWEB)

Wolery, T. J., LLNL

1995-08-28

EQ3/6 is a software package for geochemical modeling of aqueous systems, such as water/rock or waste/water rock. It is being developed for a variety of applications in geochemical studies for the Yucca Mountain Site Characterization Project. The present focus is on development of capabilities to be used in studies of geochemical processes which will take place in the near-field environment and the altered zone of the potential repository. We have completed the first year of a planned two-year effort to develop capabilities for modeling boiling processes. These capabilities will interface with other existing and future modeling capabilities to provide a means of integrating the effects of various kinds of geochemical processes in complex systems. This year, the software has been modified to allow the formation of a generalized gas phase in a closed system for which the temperature and pressure are known (but not necessarily constant). The gas phase forms when its formation is thermodynamically favored; that is, when the system pressure is equal to the sum of the partial pressures of the gas species as computed from their equilibrium fugacities. It disappears when this sum falls below that pressure. `Boiling` is the special case in which the gas phase which forms consists mostly of water vapor. The reverse process is then `condensation.` To support calculations of boiling and condensation, we have added a capability to calculate the fugacity coefficients of gas species in the system H{sub 2}O-CO{sub 2}-CH{sub 4}-H{sub 2},-Awe{sub 2}-N{sub 2},-H{sub 2}S-NH3. This capability at present is accurate only at relatively low pressures, but is adequate for all likely repository boiling conditions. We have also modified the software to calculate changes in enthalpy (heat) and volume functions. Next year we will be extending the boiling capability to calculate the pressure or the temperature at known enthalpy. We will also add an option for open system boiling.

Creation and annihilation operators for SU(3) in an SO(6,2) model

International Nuclear Information System (INIS)

Bracken, A.J.; MacGibbon, J.H.

1984-01-01

Creation and annihilation operators are defined which are Wigner operators (tensor shift operators) for SU(3). While the annihilation operators are simply boson operators, the creation operators are cubic polynomials in boson operators. Together they generate under commutation the Lie algebra of SO(6,2). A model for SU(3) is defined. The different SU(3) irreducible representations appear explicitly as manifestly covariant, irreducible tensors, whose orthogonality and normalisation properties are examined. Other Wigner operators for SU(3) can be constructed simply as products of the new creation and annihilation operators, or sums of such products. (author)

3G Bet

Institute of Scientific and Technical Information of China (English)

DAN; STEINBOCK

2006-01-01

Since the late 1990s, Chinese mobile players have caught up rapidly with cutting-edge mobile services, while the Chinese marketplace has become an R&D hub for multinational companies and a test laboratory for large-scale ad campaigns by global marketers. As China prepares to enter the third-generation (3G) industry, it is faced with both great challenges and great opportunities. Scale and mobile services In late summer 2002, Coca-Cola ran a short message service (SMS) ad campaign, featuring

Sustainable Cost Models for mHealth at Scale: Modeling Program Data from m4RH Tanzania.

Directory of Open Access Journals (Sweden)

Emily R Mangone

Full Text Available There is increasing evidence that mobile phone health interventions ("mHealth" can improve health behaviors and outcomes and are critically important in low-resource, low-access settings. However, the majority of mHealth programs in developing countries fail to reach scale. One reason may be the challenge of developing financially sustainable programs. The goal of this paper is to explore strategies for mHealth program sustainability and develop cost-recovery models for program implementers using 2014 operational program data from Mobile for Reproductive Health (m4RH, a national text-message (SMS based health communication service in Tanzania.We delineated 2014 m4RH program costs and considered three strategies for cost-recovery for the m4RH program: user pay-for-service, SMS cost reduction, and strategic partnerships. These inputs were used to develop four different cost-recovery scenarios. The four scenarios leveraged strategic partnerships to reduce per-SMS program costs and create per-SMS program revenue and varied the structure for user financial contribution. Finally, we conducted break-even and uncertainty analyses to evaluate the costs and revenues of these models at the 2014 user volume (125,320 and at any possible break-even volume.In three of four scenarios, costs exceeded revenue by $94,596, $34,443, and $84,571 at the 2014 user volume. However, these costs represented large reductions (54%, 83%, and 58%, respectively from the 2014 program cost of $203,475. Scenario four, in which the lowest per-SMS rate ($0.01 per SMS was negotiated and users paid for all m4RH SMS sent or received, achieved a $5,660 profit at the 2014 user volume. A Monte Carlo uncertainty analysis demonstrated that break-even points were driven by user volume rather than variations in program costs.These results reveal that breaking even was only probable when all SMS costs were transferred to users and the lowest per-SMS cost was negotiated with telecom partners

Sustainable Cost Models for mHealth at Scale: Modeling Program Data from m4RH Tanzania.

Science.gov (United States)

Mangone, Emily R; Agarwal, Smisha; L'Engle, Kelly; Lasway, Christine; Zan, Trinity; van Beijma, Hajo; Orkis, Jennifer; Karam, Robert

2016-01-01

There is increasing evidence that mobile phone health interventions ("mHealth") can improve health behaviors and outcomes and are critically important in low-resource, low-access settings. However, the majority of mHealth programs in developing countries fail to reach scale. One reason may be the challenge of developing financially sustainable programs. The goal of this paper is to explore strategies for mHealth program sustainability and develop cost-recovery models for program implementers using 2014 operational program data from Mobile for Reproductive Health (m4RH), a national text-message (SMS) based health communication service in Tanzania. We delineated 2014 m4RH program costs and considered three strategies for cost-recovery for the m4RH program: user pay-for-service, SMS cost reduction, and strategic partnerships. These inputs were used to develop four different cost-recovery scenarios. The four scenarios leveraged strategic partnerships to reduce per-SMS program costs and create per-SMS program revenue and varied the structure for user financial contribution. Finally, we conducted break-even and uncertainty analyses to evaluate the costs and revenues of these models at the 2014 user volume (125,320) and at any possible break-even volume. In three of four scenarios, costs exceeded revenue by $94,596, $34,443, and $84,571 at the 2014 user volume. However, these costs represented large reductions (54%, 83%, and 58%, respectively) from the 2014 program cost of $203,475. Scenario four, in which the lowest per-SMS rate ($0.01 per SMS) was negotiated and users paid for all m4RH SMS sent or received, achieved a $5,660 profit at the 2014 user volume. A Monte Carlo uncertainty analysis demonstrated that break-even points were driven by user volume rather than variations in program costs. These results reveal that breaking even was only probable when all SMS costs were transferred to users and the lowest per-SMS cost was negotiated with telecom partners. While this

Isolation and structures of sulfonium salts derived from thioethers: [{o-C(6)H(4)(CH(2)SMe)(2)}H][NbF(6)] and [{[9]aneS(3)}H][NbF(6)].

Science.gov (United States)

Jura, Marek; Levason, William; Reid, Gillian; Webster, Michael

2009-10-07

Two very unusual sulfonium salts, [{o-C(6)H(4)(CH(2)SMe)(2)}H][NbF(6)] and [{[9]aneS(3)}H][NbF(6)], obtained from reaction of the thioethers with NbF(5) in CH(2)Cl(2) solution, are reported and their structures described; the eight-coordinate tetrafluoro Nb(v) cation of the dithioether is obtained from the same reaction.

Syntheses, crystal Structures and electronic Structures of new metal chalcoiodides Bi2CuSe3I and Bi6Cu3S10I

International Nuclear Information System (INIS)

Liang, I-Chu; Bilc, Daniel I.; Manoli, Maria; Chang, Wei-Yun; Lin, Wen-Fu; Kyratsi, Theodora; Hsu, Kuei-Fang

2016-01-01

Two new metal chalcoiodides were synthesized by solid-state reactions at 400 °C. Crystal Data: Bi 2 CuSe 3 I, 1, monoclinic, C2/m, a=14.243(2) Å, b=4.1937(7) Å, c=14.647(2) Å, β=116.095(2)°, V=785.7(2) Å 3 , and Z=4; Bi 6 Cu 3 S 10 I, 2, orthorhombic, Pnma, a=17.476(2) Å, b=4.0078(4) Å, c=27.391(2) Å, V=1918.5(3) Å 3 , and Z=4. Compound 1 adopts a three-dimensional structure formed by two alternative layers, which consist of BiSe 5 square pyramids, BiSe 4 I 2 octahedra, CuSe 4 tetrahedra, and CuSe 2 I 2 tetrahedra. Compound 2 possesses a new open framework built up of BiS 5 square pyramides, BiS 6 octahedra, BiS 8 polyhedra, and CuS 4 tetrahedra where I − anions are uniquely trapped within the tunnels. Both electronic structures reveal that bismuth and chalcogenide orbitals dominate the bandgaps. The Cu d and I p states contribute to the top of valence bands, in which the distribution of I orbitals may correspond to the relative bonding interactions in 1 and 2. The optical bandgaps determined by the diffuse reflectance spectra are 0.68 eV and 0.72 eV for 1 and 2, respectively. 1 is a p-type semiconductor with high Seebeck coefficients of 460–575 μV/K in the temperature range of 300–425 K. The electrical conductivity is 0.02 S/cm at 425 K for the undoped sample. The thermal conductivity is 0.22 W/mK at 425 K. - Graphical abstract: The hybridization of chalcogenides and iodides produces two new solids Bi2CuSe3I and Bi6Cu3S10I. The I − anions participate in distinct bonding interactions within the two structures and that is consistent with the analyses of density of states. 1 is a p-type semiconductor with an optical bandgap of 0.68 eV, which possesses high Seebeck coefficient and low lattice thermal conductivity in 300–425 K.

Comparative density functional study of the complexes [UO2(CO3)3]4- and [(UO2)3(CO3)6]6- in aqueous solution.

Science.gov (United States)

Schlosser, Florian; Moskaleva, Lyudmila V; Kremleva, Alena; Krüger, Sven; Rösch, Notker

2010-06-28

With a relativistic all-electron density functional method, we studied two anionic uranium(VI) carbonate complexes that are important for uranium speciation and transport in aqueous medium, the mononuclear tris(carbonato) complex [UO(2)(CO(3))(3)](4-) and the trinuclear hexa(carbonato) complex [(UO(2))(3)(CO(3))(6)](6-). Focusing on the structures in solution, we applied for the first time a full solvation treatment to these complexes. We approximated short-range effects by explicit aqua ligands and described long-range electrostatic interactions via a polarizable continuum model. Structures and vibrational frequencies of "gas-phase" models with explicit aqua ligands agree best with experiment. This is accidental because the continuum model of the solvent to some extent overestimates the electrostatic interactions of these highly anionic systems with the bulk solvent. The calculated free energy change when three mono-nuclear complexes associate to the trinuclear complex, agrees well with experiment and supports the formation of the latter species upon acidification of a uranyl carbonate solution.

S6K1 is involved in polyploidization through its phosphorylation at Thr421/Ser424.

Science.gov (United States)

Ma, Dongchu; Yu, Huiying; Lin, Di; Sun, Yinghui; Liu, Liping; Liu, Yage; Dai, Bing; Chen, Wei; Cao, Jianping

2009-04-01

Studies on polyploidization of megakaryocytes have been hampered by the lack of synchronized polyploid megakaryocytes. In this study, a relatively synchronized polyploid cell model was successfully established by employing Dami cells treated with nocodazole. In nocodazole-induced cells, cyclin B expression oscillated normally as in diploid cells and polyploid megakaryocytes. By using the nocodazole-induced Dami cell model, we found that 4E-BP1 and Thr421/Ser424 of ribosomal S6 kinase 1(S6K1) were phosphorylated mostly at M-phase in cytoplasm and oscillated in nocodazole-induced polyploid Dami cells, concomitant with increased expression of p27 and cyclin D3. However, phosphorylation of 4E-BP1 and S6K1 on Thr421/Ser424 was significantly decreased in differentiated Dami cells induced by phorbol 12-myristate 13-acetate (PMA), concomitant with increased expression of cyclin D1 and p21 and cyclin D3. Overexpression of the kinase dead form of S6K1 containing the mutation Lys 100 --> Gln in PMA-induced Dami cells increased ploidy whereas overexpression of rapamycin-resistant form of S6K1 containing the mutations Thr421 --> Glu and Ser424 --> Asp significantly dephosphorylated 4E-BP1 and reduced expression of cyclin D1, cyclin D3, p21 and p27, and slightly decreased the ploidy of PMA-induced Dami cells, compared with treatment with PMA alone. Moreover, overexpression of rapamycin-resistant form of S6K1 significantly reversed polyploidization of nocodazole-induced Dami cells. Furthermore, MAP (a novel compound synthesized recently) partly blocked the phosphorylation of S6K1 on Thr421/Ser424 and decreased the expression of p27 and polyploidization in nocodazole-induced Dami cells. Taken together, these data suggested that S6K1/4E-BP1 pathway may play an important role in polyploidization of megakaryocytes. (c) 2008 Wiley-Liss, Inc.

The Effects of IGF-1 on TNF-α-Treated DRG Neurons by Modulating ATF3 and GAP-43 Expression via PI3K/Akt/S6K Signaling Pathway.

Science.gov (United States)

Zhang, Lei; Yue, Yaping; Ouyang, Meishuo; Liu, Huaxiang; Li, Zhenzhong

2017-05-01

Upregulation of the pro-inflammatory cytokine tumor necrosis factor α (TNF-α) is involved in the development and progression of numerous neurological disorders. Recent reports have challenged the concept that TNF-α exhibits only deleterious effects of pro-inflammatory destruction, and have raised the awareness that it may play a beneficial role in neuronal growth and function in particular conditions, which prompts us to further investigate the role of this cytokine. Insulin-like growth factor-1 (IGF-1) is a cytokine possessing powerful neuroprotective effects in promoting neuronal survival, neuronal differentiation, neurite elongation, and neurite regeneration. The association of IGF-1 with TNF-α and the biological effects, produced by interaction of IGF-1 and TNF-α, on neuronal outgrowth status of primary sensory neurons are still to be clarified. In the present study, using an in vitro model of primary cultured rat dorsal root ganglion (DRG) neurons, we demonstrated that TNF-α challenge at different concentrations elicited diverse biological effects. Higher concentration of TNF-α (10 ng/mL) dampened neurite outgrowth, induced activating transcription factor 3 (ATF3) expression, reduced growth-associated protein 43 (GAP-43) expression, and promoted GAP-43 and ATF3 coexpression, which could be reversed by IGF-1 treatment; while lower concentration of TNF-α (1 ng/mL) promoted neurite sprouting, decreased ATF3 expression, increased GAP-43 expression, and inhibited GAP-43 and ATF3 coexpression, which could be potentiated by IGF-1 supplement. Moreover, IGF-1 administration restored the activation of Akt and p70 S6 kinase (S6K) suppressed by higher concentration of TNF-α (10 ng/mL) challenge. In contrast, lower concentration of TNF-α (1 ng/mL) had no significant effect on Akt or S6K activation, and IGF-1 administration activated these two kinases. The effects of IGF-1 were abrogated by phosphatidylinositol 3-kinase (PI3K) inhibitor LY294002. These data

Growth and Characterization of Organic Based Marine Dye NLO Material: 7-Bromo-6-chloro-3-[3-[(2R, 3S-3-hydroxy-2-piperidyl]-2-oxopropyl]-4(3H-quinazolinone

Directory of Open Access Journals (Sweden)

M. Jayandran

2011-01-01

Full Text Available An organic marine dye compound (7-bromo-6-chloro-3-[3-[(2R, 3S-3-hydroxy-2-piperidyl]-2-oxopropyl]-4(3H-quinazolinone was synthesized. The characteristics of this dye is soluble in water. The organic compound was made into a crystal by slow evaporation technique. The grown crystals were characterized by single crystal x-ray diffraction (XRD analysis, FTIR studies and UV-visible transmittance studies and the NLO activity of the grown crystal has been checked by second harmonic generation (SHG test.

Electrical and optical modeling of poly(3-hexylthiophene):[6,6]-phenyl-C61 butyric acid methyl ester P3HT-PCBM bulk heterojunction solar cells

Science.gov (United States)

Brioua, Fathi; Remram, Mohamed; Nechache, Riad; Bourouina, Hicham

2017-11-01

In this work, we investigate a two-dimensional theoretical model for the photon conversion through an integration of the optical and electrical part of multilayer system in a bulk heterojunction solar cell based on poly(3-hexylthiophene) (P3HT)/6,6-phenyl C61-butyric acid methyl ester (PCBM) blend. The optical properties of the studied structure ITO/PEDOT:PSS/P3HT:PCBM/Ca/Al, such as the exciton generation rate and the electrical field distribution, are predicted at vicinity of the active layer and have been used to solve Poisson and continuity, drift-diffusion equations of the electrical model which characterize the electrical behavior of semiconductor device using finite element method (FEM). The electrical parameters such as power conversion efficiency (PCE), open voltage circuit ( V oc), short-circuit current density ( J sc) and fill factor (FF) are extracted from the current-voltage (J-V) characteristics under illumination and in dark conditions. Highest external quantum efficiency (IPCE), up to 60%, is obtained around 520 nm, while a power conversion efficiency (PCE) value of 3.62% is found to be in good agreement with the literature results. Integration of such theoretical approach into technological applications dealing with optoelectrical material performance will rapidly provide to the user accurate data outputs required for efficient validation of proof-of-concepts.

Synthesis and characterization of sulfur-voided cubanes. Structural analogues for the MoFe(3)S(3) subunit in the nitrogenase cofactor.

Science.gov (United States)

Coucouvanis, Dimitri; Han, Jaehong; Moon, Namdoo

2002-01-16

A new class of Mo/Fe/S clusters with the MoFe(3)S(3) core has been synthesized in attempts to model the FeMo-cofactor in nitrogenase. These clusters are obtained in reactions of the (Cl(4)-cat)(2)Mo(2)Fe(6)S(8)(PR(3))(6) [R = Et (I), (n)Pr (II)] clusters with CO. The new clusters include those preliminarily reported: (Cl(4)-cat)MoFe(3)S(3)(PEt(3))(2)(CO)(6) (III), (Cl(4)-cat)(O)MoFe(3)S(3)(PEt(3))(3)(CO)(5) (IV), (Cl(4)-cat)(Pyr)MoFe(3)S(3)(PEt(3))(2)(CO)(6) (VI), and (Cl(4)-cat)(Pyr)MoFe(3)S(3)(P(n)Pr(3))(3)(CO)(4) (VIII). In addition the new (Cl(4)-cat)(O)MoFe(3)S(3)(P(n)Pr(3))(3)(CO)(5) cluster (IVa), the (Cl(4)-cat)(O)MoFe(3)S(3)(PEt(3))(2)(CO)(6)cluster (V), the (Cl(4)-cat)(O)MoFe(3)S(3)(P(n)Pr(3))(2)(CO)(6) cluster (Va), the (Cl(4)-cat)(Pyr)MoFe(3)S(3)(P(n)Pr(3))(2)(CO)(6) cluster (VIa), and the (Cl(4)-cat)(P(n)Pr(3))MoFe(3)S(3)(P(n)Pr(3))(2)(CO)(6) cluster (VII) also are reported. Clusters III-VIII have been structurally and spectroscopically characterized. EPR, zero-field (57)Fe-Mössbauer spectroscopic characterizations, and magnetic susceptibility measurements have been used for a tentative assignment of the electronic and oxidation states of the MoFe(3)S(3) sulfur-voided cuboidal clusters. A structural comparison of the clusters with the MoFe(3)S(3) subunit of the FeMo-cofactor has led to the suggestion that the storage of reducing equivalents into M-M bonds, and their use in the reduction of substrates, may occur with the FeMo-cofactor, which also appears to have M-M bonding. On the basis of this argument, a possible N(2)-binding and reduction mechanism on the FeMoco-cofactor is proposed.

Short Message Service (SMS) Texting Symbols: A Functional Analysis of 10,000 Cellular Phone Text Messages

Science.gov (United States)

Beasley, Robert E.

2009-01-01

The purpose of this study was to investigate the use of symbolic expressions (e.g., "BTW," "LOL," "UR") in an SMS text messaging corpus consisting of over 10,000 text messages. More specifically, the purpose was to determine, not only how frequently these symbolic expressions are used, but how they are utilized in terms of the language functions…

Urenco`s experience of UF{sub 6} handling

Energy Technology Data Exchange (ETDEWEB)

Saelmans, F. [Urenco Almelo (Netherlands); Scane, C. [Urenco Capenhurst (United Kingdom); Christofzik, J. [Urenco Gronau (Germany)

1991-12-31

Urenco operates enrichment plants at three sites, Almelo (Netherlands), Capenhurst (United Kingdom) and Gronau (Germany). Current installed separative work capacity is 2,500 tSWpa. Since 1971, when the first pilot plants were built, enrichment production has totalled 18,000 tSW. During this last 20 years over 3,500 48 containers of UF{sub 6} have been fed to the plants, over 3,700 30 containers have been filled with product and delivered successfully to Urenco`s customers worldwide and over 3,000 48 containers of depleted tails have been filled and have either been returned to customers or retained for long term storage on site. The paper gives a brief outline of Urenco`s experience in handling UF{sub 6}: the equipment and methods used in receiving, feeding, filling, blending, liquid sampling, storing, moving on site and despatching of UF{sub 6} containers. Some of the difficulties experienced with UF{sub 6} containers are appended.

The microscopic model of BiFeO3

Science.gov (United States)

Fishman, R. S.

2018-05-01

Many years and great effort have been spent constructing the microscopic model for the room temperature multiferroic BiFeO3. However, earlier models implicitly assumed that the cycloidal wavevector q was confined to one of the three-fold symmetric axes in the hexagonal plane normal to the electric polarization. Because recent measurements indicate that q can be rotated by a magnetic field, it is essential to properly treat the anisotropy that confines q at low fields. We propose that the anisotropy energy -K3S6sin6 θ cos 6 ϕ confines the wavevectors q to the three-fold axis ϕ = 0 and ± 2 π / 3 within the hexagonal plane with θ = π / 2 .

Growth, thermal and spectral characteristics of Yb{sup 3+}:Sr{sub 6}YSc(BO{sub 3}){sub 6} crystal

Energy Technology Data Exchange (ETDEWEB)

Yuan, Feifei [Key Laboratory of Optoelectronic Materials Chemistry and Physics, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou 350002 (China); University of Chinese Academy of Sciences, Beijing 100049 (China); Zhang, Lizhen; Huang, Yisheng; Sun, Shijia [Key Laboratory of Optoelectronic Materials Chemistry and Physics, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou 350002 (China); Lin, Zhoubin, E-mail: lzb@fjirsm.ac.cn [Key Laboratory of Optoelectronic Materials Chemistry and Physics, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou 350002 (China); Wang, Guofu [Key Laboratory of Optoelectronic Materials Chemistry and Physics, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou 350002 (China)

2014-09-15

Highlights: • A new crystal of Yb{sup 3+}:Sr{sub 6}YSc(BO{sub 3}){sub 6} was grown successfully from a Li{sub 6}B{sub 4}O{sub 9} flux. • Yb{sup 3+}:Sr{sub 6}YSc(BO{sub 3}){sub 6} crystal has good thermal, mechanical and spectral properties. • Yb{sup 3+}:Sr{sub 6}YSc(BO{sub 3}){sub 6} has long fluorescence lifetime, broad absorption and emission bands. - Abstract: A crystal of Yb{sup 3+}:Sr{sub 6}YSc(BO{sub 3}){sub 6} was grown successfully from Li{sub 6}B{sub 4}O{sub 9} flux by the top-seeded solution growth method. The crystal's thermal, mechanical and spectral characteristics were investigated in detail. It possesses small thermal expansion coefficients, moderate thermal conductivities, and large hardness. The crystal has a strong absorption band at 967 nm with a full width at half-maximum of about 3.4 nm. The crystal has a broad emission band at 1016 nm with the full width at half-maximum of about 64 nm. The emission cross sections were calculated by reciprocity method and Füchtbauer-Ladenburg formula. The fluorescence lifetime is 5.98 ms. The results reveal that Yb{sup 3+}:Sr{sub 6}YSc(BO{sub 3}){sub 6} crystal is a new promising tunable and ultrashort pulse laser crystal.

Supersymmetric extension of Hopf maps: N = 4 {sigma}-models and the S{sup 3} {yields} S{sup 2} fibration

Energy Technology Data Exchange (ETDEWEB)

Carvalho, L. Faria; Toppan, F., E-mail: leofc@cbpf.b, E-mail: toppan@cbpf.b [Centro Brasileiro de Pesquisas Fisicas (CBPF), Rio de Janeiro, RJ (Brazil); Kuznetsova, Z., E-mail: zhanna.kuznetsova@ufabc.edu.b [Universidade Federal do ABC (UFABC), Santo Andre, SP (Brazil)

2009-07-01

We discuss four off-shell N = 4 D = 1 supersymmetry transformations, their associated one-dimensional -models and their mutual relations. They are given by I - the (4, 4){sub lin} linear 'root' supermultiplet (supersymmetric extension of R{sup 4}), II - the (3, 4, 1){sub lin} linear supermultiplet (supersymmetric extension of R3), III - the (3, 4, 1){sub nl} non-linear supermultiplet living on S{sup 3} and IV - the (2, 4, 2){sub nl} non-linear supermultiplet living on S{sup 2}. The I {yields} II map is the supersymmetric extension of the R4 {yields} R3 bilinear map, while the II {yields} IV map is the supersymmetric extension of the S{sup 3} {yields} S{sup 2} first Hopf fibration. The restrictions on the S{sup 3}, S{sup 2} spheres are expressed in terms of the stereo graphic projections. The non-linear supermultiplets, whose super transformations are local differential polynomials, are not equivalent to the linear supermultiplets with the same field content. The -models are determined in terms of an unconstrained pre potential of the target coordinates. The Uniformization Problem requires solving an inverse problem for the pre potential. The basic features of the supersymmetric extension of the second and third Hopf maps are briefly sketched. Finally, the Schur's lemma (i.e. the real, complex or quaternionic property) is extended to all minimal linear supermultiplets up to N {<=} 8. (author)

Transport of trans-tiliroside (kaempferol-3-β-D-(6"-p-coumaroyl-glucopyranoside) and related flavonoids across Caco-2 cells, as a model of absorption and metabolism in the small intestine.

Science.gov (United States)

Luo, Zijun; Morgan, Michael R A; Day, Andrea J

2015-01-01

1. Absorption and metabolism of tiliroside (kaempferol 3-β-D-(6"-p-coumaroyl)-glucopyranoside) and its related compounds kaempferol, kaempferol-3-glucoside and p-coumaric acid were investigated in the small intestinal Caco-2 cell model. Apparent permeation (Papp) was determined as 0.62 × 10(-6) cm/s, 3.1 × 10(-6) cm/s, 0 and 22.8 × 10(-6) cm/s, respectively. 2. Mechanistic study showed that the transportation of tiliroside, kaempferol-3-glucoside and p-coumaric acid in Caco-2 model were transporter(s) involved, while transportation of kaempferol was solely by passive diffusion mechanism. 3. Efflux transporters, multi-drug-resistance-associated protein-2 (MRP2), were shown to play a role in limiting the uptake of tiliroside. Inhibitors of MRP2, (MK571 and rifampicin) and co-incubation with kaempferol (10 μM), increased transfer from the apical to the basolateral side by three to five fold. 4. Metabolites of kaempferol-3-glucoside and p-coumaric acid were not detected in the current Caco-2 model, while tiliroside was metabolised to a limited extent, with two tiliroside mono-glucuronides identified; and kaempferol was metabolised to a higher extent, with three mono-glucuronides and two mono-sulfates identified. 5. In conclusion, tiliroside was metabolised and transported across Caco-2 cell membrane to a limited extent. Transportation could be increased by applying MRP2 inhibitors or co-incubation with kaempferol. It is proposed that tiliroside can be absorbed by human; future pharmacokinetics studies are warranted in order to determine the usefulness of tiliroside as a bioactive agent.

S/sup 3/ Financial Projection Model: preliminary user's manual and system overview

Energy Technology Data Exchange (ETDEWEB)

Masso, J. F.

1976-11-30

The S/sup 3/ Financial Projection Model is an effort undertaken to construct a pipeline economic model in order to satisfy the requirements of the US ERDA program: Energy Study of Pipeline Transportation System. A brief outline of this process is described in Appendix A, Background on the S/sup 3/ Development of a Pipeline Economic Model. A general overview of the model is presented first to indicate the rationale underlying the model and to show the linkages between the various submodels. An understanding of the basic accounting definitions and self-evident relationships between line items in the general financial accounting reports is a prerequisite for the effective application of the model. Particular attention has been paid in this system description to defining the methods of calculations utilized by the model and to describing the optional capital investment planning techniques that may be exercised with the model. The mathematical relationships underlying various planning techniques are defined and the methods for applying these techniques are discussed with illustrations and sample input data specifications. Decision tables are used to show complex decision rules applied within the model to determine the logical flow of a particular computational routine. The complete set of source data and model options are described along with the procedures for input data preparation and actual program operation.

Equation of state and hyperfine parameters of high-spin bridgmanite in the Earth’s lower mantle by synchrotron X-ray diffraction and Mössbauer spectroscopy

Energy Technology Data Exchange (ETDEWEB)

Mao, Zhu; Wang, Fan; Lin, Jung-Fu; Fu, Suyu; Yang, Jing; Wu, Xiang; Okuchi, Takuo; Tomioka, Naotaka; Prakapenka, Vitali B.; Xiao, Yuming; Chow, Paul

2017-02-01

In this study, we performed synchrotron X-ray diffraction (XRD) and Mössbauer spectroscopy (SMS) measurements on two single-crystal bridgmanite samples [ Embedded Image and Embedded Image ] to investigate the combined effect of Fe and Al on the hyperfine parameters, lattice parameters, and equation of state (EoS) of bridgmanite up to 130 GPa. Our SMS results show that Fe2+ and Fe3+ in Bm6 and Al-Bm11 are predominantly located in the large pseudo-dodecahedral sites (A-site) at lower-mantle pressures. The observed drastic increase in the hyperfine quadrupole splitting (QS) between 13 and 32 GPa can be associated with an enhanced local distortion of the A-site Fe2+ in Bm6. In contrast to Bm6, the enhanced lattice distortion and the presence of extremely high QS values of Fe2+ are not observed in Al-Bm11 at high pressures. Our results here support the notion that the occurrence of the extremely high QS component of approximately 4 mm/s in bridgmanite is due to the lattice distortion in the high-spin (HS) A-site Fe2+, instead of the occurrence of the intermediate-spin state. Both A-site Fe2+ and Fe3+ in Bm6 and Al-Bm11 remain in the HS state at lower-mantle pressures. Together with XRD results, we present the first experimental evidence that the enhanced lattice distortion of A-site Fe2+ does not cause any detectable variation in the EoS parameters, but is associated with anomalous variations in the bond length, tilting angle, and shear strain in the octahedra of Bm6. Analysis of the obtained EoS parameters of bridgmanite at lower-mantle pressures indicates that the substitution of Fe in bridgmanite will cause an enhanced density and a reduced bulk sound velocity (VΦ), whereas the Al and Fe substitution has a reduced effect on density and a negligible effect on VΦ. These experimental results provide new insight into the correlation between lattice, hyperfine, and EoS parameters of bridgmanite in the Earth’s lower mantle.

Exotic Higgs decays in a neutrino mass model with discrete S3 symmetry

CERN Document Server

Bhattacharyya, G; Päs, H

2010-01-01

Exotic Higgs decays can arise in lepton flavor models with horizontal symme- tries. We investigate the scalar sector of a neutrino mass model using an S3 family symmetry as an example. The model’s symmetry leads to an enlarged scalar sector with features that might be used to test the model experimentally, such as scalar particles with masses below 1 TeV and manifestly non-zero ma- trix elements for lepton flavor violating decays. We compare different decay channels of the scalars as well as leptonic processes that violate lepton flavor, in order to compare model predictions with experimental bounds.

P- and S-wave velocity models incorporating the Cascadia subduction zone for 3D earthquake ground motion simulations—Update for Open-File Report 2007–1348

Science.gov (United States)

Stephenson, William J.; Reitman, Nadine G.; Angster, Stephen J.

2017-12-20

In support of earthquake hazards studies and ground motion simulations in the Pacific Northwest, threedimensional (3D) P- and S-wave velocity (VP and VS , respectively) models incorporating the Cascadia subduction zone were previously developed for the region encompassed from about 40.2°N. to 50°N. latitude, and from about 122°W. to 129°W. longitude (fig. 1). This report describes updates to the Cascadia velocity property volumes of model version 1.3 ([V1.3]; Stephenson, 2007), herein called model version 1.6 (V1.6). As in model V1.3, the updated V1.6 model volume includes depths from 0 kilometers (km) (mean sea level) to 60 km, and it is intended to be a reference for researchers who have used, or are planning to use, this model in their earth science investigations. To this end, it is intended that the VP and VS property volumes of model V1.6 will be considered a template for a community velocity model of the Cascadia region as additional results become available. With the recent and ongoing development of the National Crustal Model (NCM; Boyd and Shah, 2016), we envision any future versions of this model will be directly integrated with that effort

GREEN BANK TELESCOPE OBSERVATIONS OF THE NH3 (3, 3) AND (6, 6) TRANSITIONS TOWARD SAGITTARIUS A MOLECULAR CLOUDS

International Nuclear Information System (INIS)

Minh, Young Chol; Liu, Hauyu Baobab; Ho, Paul T. P.; Hsieh, Pei-Ying; Su, Yu-Nung; Kim, Sungsoo S.; Wright, Melvyn

2013-01-01

Ammonia (3, 3) and (6, 6) transitions have been observed using the Green Bank Telescope toward the Sgr A region. The gas is mainly concentrated in 50 km s –1 and 20 km s –1 clouds located in a plane inclined to the galactic plane. These 'main' clouds appear to be virialized and influenced by the expansion of the supernova remnant Sgr A East. The observed emission shows very complicated features in the morphology and velocity structure. Gaussian multi-component fittings of the observed spectra revealed that various 'streaming' gas components exist all over the observed region. These components include those previously known as 'streamers' and 'ridges', but most of these components appear not to be directly connected to the major gas condensations (the 50 km s –1 and 20 km s –1 clouds). They are apparently located out of the galactic plane, and they may have a different origin than the major gas condensations. Some of the streaming components are expected to be sources that feed the circumnuclear disk of our Galactic center directly and episodically. They may also evolve differently than major gas condensations under the influence of the activities of the Galactic center

Expression of the cytochrome P450s, CYP6P3 and CYP6M2 are significantly elevated in multiple pyrethroid resistant populations of Anopheles gambiae s.s. from Southern Benin and Nigeria

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Ranson Hilary

2008-11-01

Full Text Available Abstract Background Insecticide resistance in Anopheles mosquitoes is threatening the success of malaria control programmes. This is particularly true in Benin where pyrethroid resistance has been linked to the failure of insecticide treated bed nets. The role of mutations in the insecticide target sites in conferring resistance has been clearly established. In this study, the contribution of other potential resistance mechanisms was investigated in Anopheles gambiae s.s. from a number of localities in Southern Benin and Nigeria. The mosquitoes were sampled from a variety of breeding sites in a preliminary attempt to investigate the role of contamination of mosquito breeding sites in selecting for resistance in adult mosquitoes. Results All mosquitoes sampled belonged to the M form of An. gambiae s.s. There were high levels of permethrin resistance in an agricultural area (Akron and an urban area (Gbedjromede, low levels of resistance in mosquito samples from an oil contaminated site (Ojoo and complete susceptibility in the rural Orogun location. The target site mutation kdrW was detected at high levels in two of the populations (Akron f = 0.86 and Gbedjromede f = 0.84 but was not detected in Ojoo or Orogun. Microarray analysis using the Anopheles gambiae detox chip identified two P450s, CYP6P3 and CYP6M2 up regulated in all three populations, the former was expressed at particularly high levels in the Akron (12.4-fold and Ojoo (7.4-fold populations compared to the susceptible population. Additional detoxification and redox genes were also over expressed in one or more populations including two cuticular pre-cursor genes which were elevated in two of the three resistant populations. Conclusion Multiple resistance mechanisms incurred in the different breeding sites contribute to resistance to permethrin in Benin. The cytochrome P450 genes, CYP6P3 and CYP6M2 are upregulated in all three resistant populations analysed. Several additional potential

The Effect of Education through Short Message Service (SMS) Messages on Diabetic Patients Adherence.

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Adikusuma, Wirawan; Qiyaam, Nurul

2017-05-12

Poor adherence and a lack of understanding of medication instructions for oral antidiabetic use are key factors that inhibit the control of glycemic levels. The aforementioned situation needs intervention to improve medication adherence and the therapy. This study was conducted with a quasi-experimental design with prospective data collection. The subjects of this study were 50 outpatients with type 2 diabetes melitus (T2DM) who had received oral antidiabetic medicine therapy at least six months prior to adherence measurement. The patients were classified into two groups-the control group and the intervention group. The intervention group received Short Message Service (SMS) messages of diabetes education, while the control group did not. Data collection was conducted by doing interviews and administering the Morisky Medication Adherence Scale (MMAS) questionnaire. The results showed the increase in adherence in the intervention group as 1.15 ± 1.04 and that in the control group as 0.72 ± 0.90. These results indicated that there were significant differences in MMAS score between the control and intervention groups ( p < 0.05). The decrease in fasting blood glucose and glucose measured 2 h postprandially was greater in the intervention group than that in the control group. It was concluded that the provision of education through SMS had a positive effect on medication adherence and glycemic levels.

Model structure of the stream salmonid simulator (S3)—A dynamic model for simulating growth, movement, and survival of juvenile salmonids

Science.gov (United States)

Perry, Russell W.; Plumb, John M.; Jones, Edward C.; Som, Nicholas A.; Hetrick, Nicholas J.; Hardy, Thomas B.

2018-04-06

Fisheries and water managers often use population models to aid in understanding the effect of alternative water management or restoration actions on anadromous fish populations. We developed the Stream Salmonid Simulator (S3) to help resource managers evaluate the effect of management alternatives on juvenile salmonid populations. S3 is a deterministic stage-structured population model that tracks daily growth, movement, and survival of juvenile salmon. A key theme of the model is that river flow affects habitat availability and capacity, which in turn drives density dependent population dynamics. To explicitly link population dynamics to habitat quality and quantity, the river environment is constructed as a one-dimensional series of linked habitat units, each of which has an associated daily time series of discharge, water temperature, and usable habitat area or carrying capacity. The physical characteristics of each habitat unit and the number of fish occupying each unit, in turn, drive survival and growth within each habitat unit and movement of fish among habitat units.The purpose of this report is to outline the underlying general structure of the S3 model that is common among different applications of the model. We have developed applications of the S3 model for juvenile fall Chinook salmon (Oncorhynchus tshawytscha) in the lower Klamath River. Thus, this report is a companion to current application of the S3 model to the Trinity River (in review). The general S3 model structure provides a biological and physical framework for the salmonid freshwater life cycle. This framework captures important demographics of juvenile salmonids aimed at translating management alternatives into simulated population responses. Although the S3 model is built on this common framework, the model has been constructed to allow much flexibility in application of the model to specific river systems. The ability for practitioners to include system-specific information for the

Report of chronic myeloid leukemia SMS Medical College Hospital, Jaipur.

Science.gov (United States)

Malhotra, Hemant; Sharma, Rajesh; Singh, Yogender; Chaturvedi, Hemant

2013-07-01

This is a retrospective analysis of patients of chronic myeloid leukemia (CML) registered and under treatment at the Leukemia Lymphoma Clinic at the Birla Cancer Center, SMS Medical College Hospital, Jaipur. Approximately, two-thirds of the patients are getting imatinib mesylate (IM) through the Glivec International Patient Assistance Program while the rest are on generic IM. In addition to comparison of hematological and molecular responses in the Glivec versus the genetic group, in this analysis, an attempt is also made to assess the socio-economic (SE) status of the patients and its effect on the response rates. Of the 213 patients studied, most (28.6%) are in the age group between 30 years and 40 years and the mean age of the patients in 39 years, a good decade younger that in the west. There is a suggestion that patients in lower SE class present with higher Sokal scores and with more disease burden. Possibly hematological responses are similar with both Glivec and generic IM. No comment can be made with regards to molecular response between the two groups as a significant number of patients in the Glivec arm (42%) do not have molecular assessment because of economic reasons. CML is a common and challenging disease in the developing world with patients presenting at an earlier age with more advanced disease. SE factors play a significant role in therapy and disease monitoring decision making and may impact on response rates and prognosis.

Spinning strings in AdS3×S3 with NS–NS flux

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Rafael Hernández

2014-11-01

Full Text Available The sigma model describing closed strings rotating in AdS3×S3 is known to reduce to the one-dimensional Neumann–Rosochatius integrable system. In this article we show that closed spinning strings in AdS3×S3×T4 in the presence of NS–NS three-form flux can be described by an extension of the Neumann–Rosochatius system. We consider closed strings rotating with one spin in AdS3 and two different angular momenta in S3. For a class of solutions with constant radii we find the dependence of the classical energy on the spin and the angular momenta as an expansion in the square of the 't Hooft coupling of the theory.

Electrical conductivity studies in (Ag3AsS3)x(As2S3)1-x superionic glasses and composites

Science.gov (United States)

Studenyak, I. P.; Neimet, Yu. Yu.; Kranjčec, M.; Solomon, A. M.; Orliukas, A. F.; Kežionis, A.; Kazakevičius, E.; Šalkus, T.

2014-01-01

Compositional, frequency, and temperature studies of impedance and electrical conductivity in (Ag3AsS3)x(As2S3)1-x superionic glasses and composites were performed. Frequency range from 10 Hz to 3 × 109 Hz and temperature interval 300-400 K were used for the measurements. Compositional dependences of electrical conductivity and activation energy are analyzed; the most substantial changes are observed with the transition from (Ag3AsS3)0.4(As2S3)0.6 glass to (Ag3AsS3)0.5(As2S3)0.5 composite. With increase of Ag3AsS3 content, the investigated materials are found to have crystalline inclusions and show the two-phase composite nature. Addition of Ag3AsS3 leads to the increase of electrical conductivity whereas the activation energy decreases.

The glutamate receptor GluR5 agonist (S)-2-amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic acid and the 8-methyl analogue

DEFF Research Database (Denmark)

Clausen, Rasmus Prætorius; Naur, Peter; Kristensen, Anders Skov

2009-01-01

The design, synthesis, and pharmacological characterization of a highly potent and selective glutamate GluR5 agonist is reported. (S)-2-Amino-3-((RS)-3-hydroxy-8-methyl-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic acid (5) is the 8-methyl analogue of (S)-2-amino-3-(3-hydroxy-7,8-dihydro-6H......-cyclohepta[d]isoxazol-4-yl)propionic acid ((S)-4-AHCP, 4). Compound 5 displays an improved selectivity profile compared to 4. A versatile stereoselective synthetic route for this class of compounds is presented along with the characterization of the binding affinity of 5 to ionotropic glutamate receptors (i......GluRs). Functional characterization of 5 at cloned iGluRs using a calcium imaging assay and voltage-clamp recordings show a different activation of GluR5 compared to (S)-glutamic acid (Glu), kainic acid (KA, 1), and (S)-2-amino-3-(3-hydroxy-5-tert-butyl-4-isoxazolyl)propionic acid ((S)-ATPA, 3) as previously...

Reactivity of Cubane-Type [(OC)(3)MFe(3)S(4)(SR)(3)](3-) Clusters (M = Mo, W): Interconversion with Cuboidal [Fe(3)S(4)](0) Clusters and Electron Transfer.

Science.gov (United States)

Raebiger, James W.; Crawford, Charles A.; Zhou, Jian; Holm, R. H.

1997-03-12

The title clusters, several examples of which have been reported earlier, have been prepared by two different methods and subjected to structural and reactivity studies. The compounds (Et(4)N)(3)[(OC)(3)MFe(3)S(4)(Smes)(3)].MeCN (M = Mo/W) are isomorphous and crystallize in monoclinic space group P2(1)/n with a = 13.412(1)/13.297(1) Å, b = 19.0380(1)/18.9376(3) Å, c = 26.4210(1)/26.2949(1) Å, beta = 97.87(1)/97.549(1) degrees, and Z = 4. The clusters contain long M-S (2.62/2.59 Å) and M-Fe (3.22/3.19 Å) bonds, consistent with the reported structure of [(OC)(3)MoFe(3)S(4)(SEt)(3)](3-) (3). Reaction of [(OC)(3)MoFe(3)S(4)(LS(3))](3-) (7) with CO in the presence of NaPF(6) affords cuboidal [Fe(3)S(4)(LS(3))](3-) (9), also prepared in this laboratory by another route as a synthetic analogue of protein-bound [Fe(3)S(4)](0) clusters. The clusters [Fe(3)S(4)(SR)(3)](3-) (R = mes, Et), of limited stability, were generated by the same reaction. Treatment of 9 with [M(CO)(3)(MeCN)(3)] affords 7 and its M = W analogue. The clusters [(OC)(3)MFe(3)S(4)(SR)(3)](3-) form a four-member electron transfer series in which the 3- cluster can be once reduced (4-) and twice oxidized (2-, 1-) to afford clusters of the indicated charges. The correct assignment of redox couple to potential in the redox series of six clusters is presented, correcting an earlier misassignment of the redox series of 3. Carbonyl stretching frequencies are shown to be sensitive to cluster oxidation state, showing that the M sites and Fe(3)S(4) fragments are electronically coupled despite the long bond distances. (LS(3) = 1,3,5-tris((4,6-dimethyl-3-mercaptophenyl)thio)-2,4,6-tris(p-tolylthio)benzenate(3-); mes = mesityl.)

Identification of the transition arrays 3d74s-3d74p in Br X and 3d64s-3d64p in Br XI

International Nuclear Information System (INIS)

Zeng, X.T.; Jupen, C.; Bengtsson, P.; Engstroem, L.; Westerlind, M.; Martinson, I.

1991-01-01

We report a beam-foil study of multiply ionized bromine in the region 400-1300A, performed with 6 and 8 MeV Br ions from a tandem accelerator. At these energies transitions belonging to Fe-like Br X and Mn-like Br XI are expected to be prominent. We have identified 31 lines as 3d 7 4s-3d 7 4p transitions in Br X, from which 16 levels of the previously unknown 3d 7 4s configuration could be established. We have also added 6 new 3d 7 4p levels to the 99 previously known. For Br XI we have classified 9 lines as 3d 6 4s-3d 6 4p combinations. The line identifications have been corroborated by isoelectronic comparisons and theoretical calculations using the superposition-of-configurations technique. (orig.)

An Investigation of the Impact of an Intervention to Reduce Academic Procrastination Using Short Message Service (SMS) Technology

Science.gov (United States)

Davis, Darrel R.; Abbitt, Jason T.

2013-01-01

This mixed-method pilot study investigated the impact of a custom Short Message Service (SMS) reminder system developed to help students reduce procrastination and increase performance on weekly content-related quizzes in a high-enrollment hybrid online course. Text message reminders were sent to three students with high procrastination and low…

Short-interval SMS wind vector determinations for a severe local storms area

Science.gov (United States)

Peslen, C. A.

1980-01-01

Short-interval SMS-2 visible digital image data are used to derive wind vectors from cloud tracking on time-lapsed sequences of geosynchronous satellite images. The cloud tracking areas are located in the Central Plains, where on May 6, 1975 hail-producing thunderstorms occurred ahead of a well defined dry line. Cloud tracking is performed on the Goddard Space Flight Center Atmospheric and Oceanographic Information Processing System. Lower tropospheric cumulus tracers are selected with the assistance of a cloud-top height algorithm. Divergence is derived from the cloud motions using a modified Cressman (1959) objective analysis technique which is designed to organize irregularly spaced wind vectors into uniformly gridded wind fields. The results demonstrate the feasibility of using satellite-derived wind vectors and their associated divergence fields in describing the conditions preceding severe local storm development. For this case, an area of convergence appeared ahead of the dry line and coincided with the developing area of severe weather. The magnitude of the maximum convergence varied between -10 to the -5th and -10 to the -14th per sec. The number of satellite-derived wind vectors which were required to describe conditions of the low-level atmosphere was adequate before numerous cumulonimbus cells formed. This technique is limited in areas of advanced convection.

{μ-2-[4-(1,3-Benzothiazol-2-ylphenyl]-2-azapropane-1,3-dithiolato-κ4S,S′:S,S′}bis[tricarbonyliron(I

Directory of Open Access Journals (Sweden)

Da-yong Jiang

2012-03-01

Full Text Available The title compound, [Fe2(C15H12N2S3(CO6], was prepared as an azadithiolatodiiron model for the active site of [FeFe]-hydrogenase. The Fe2S2 core adopts a butterfly shape, with each metal having a pseudo square-pyramidal geometry. The N-substituted azadithiolate is μ2-κ4S,S′:S,S′-coordinated to the Fe(CO3 moieties to form two fused six-membered rings with different conformations. The sum of the C—N—C angles around the N atom [356.85 (15°] indicates a flattening of the trigonal–pyramidal geometry about the N atom and an increase in the degree of sp2-hybridization.

In silico binding affinity studies of N-9 substituted 6-(4-(4-propoxyphenylpiperazin-1-yl-9H-purine derivatives-Target for P70-S6K1 & PI3K-δ kinases

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Manjunath G. Sunagar

2018-03-01

Full Text Available P70-S6K1 & PI3K-δ kinases are identified to be involved in many physiological processes associated with cancer, therefore many of the inhibitors being designed to target these kinases are in clinical trials. In the current study we have exploited the N-9 substituted 6-(4-(4-propoxyphenyl piperazin-1-yl-9H-purine derivatives for their inhibitory properties with the above kinases. We have used an in silico docking study with seventeen purine derivatives for their binding affinity calculations. The binding affinities of these small molecules with P70-S6K1 & PI3K-δ were performed using AutoDock Vina. Among all the compounds, PP16 showed highest binding affinity of −14.7 kcal/mol with P70-S6K1 kinase & −17.2 kcal/mol with PI3K-δ kinases as compared to the molecules under clinical trials (PF-4708671 & IC-87114. Docking studies revealed that N-9 coumarine substituted purine derivative could be one of the potential ligands for the inhibition of P70-S6K1 & PI3K-δ kinases. Hence, this compound can be further investigated by in vitro and in vivo experiments for further validation.

Pressure induced phase transition in Pb6Bi2S9

DEFF Research Database (Denmark)

Olsen, Lars Arnskov; Friese, Karen; Makovicky, Emil

2011-01-01

consists of two types of moduli with SnS/TlI archetype structure in which the Pb and Bi lone pairs are strongly expressed. The mechanism of the phase transition is described in detail and the results are compared to the closely related phase transition in Pb3Bi2S6 (lillianite).......The crystal structure of Pb6Bi2S9 is investigated at pressures between 0 and 5.6 GPa with X-ray diffraction on single-crystals. The pressure is applied using diamond anvil cells. Heyrovskyite (Bbmm, a = 13.719(4) Å, b = 31.393(9) Å, c = 4.1319(10) Å, Z = 4) is the stable phase of Pb6Bi2S9...... at ambient conditions and is built from distorted moduli of PbS-archetype structure with a low stereochemical activity of the Pb2+ and Bi3+ lone electron pairs. Heyrovskyite is stable until at least 3.9 GPa and a first-order phase transition occurs between 3.9 and 4.8 GPa. A single-crystal is retained after...

Facile synthesis of some novel 2-substituted-4,6-diarylpyrimidines using 4 ' -hydroxy-3 ' ,5 ' -dinitrochalcones and S-benzylthiouronium chloride

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K. L. Ameta

2012-01-01

Full Text Available Various 4'-hydroxy-3',5'-dinitro substituted chalcones 1 and S-benzylthiouronium chloride (SBT 2 in the presence of DMF-organic bases (morpholine/ pyrrolidine/ piperidine gave 4,6-diaryl-2-(4-morpholinyl / 1-pyrrolidinyl /1-piperidinyl- pyrimidines 4, 5 and 6 in a facile one-pot conversion. In an another attempt reactants 1 and 2 yielded intermediate 2-benzylthiopyrimidines 3, in presence of DMF, which on treatment with heterocyclic secondary amines gave products 4, 5 and 6 in an alternate two-step process.

The minimal extension of the Standard Model with S3 symmetry

International Nuclear Information System (INIS)