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Sample records for modeling william welch

  1. The Brief Military Career of Dr. William H. Welch.

    Science.gov (United States)

    Gilman, James K

    2017-03-01

    The purpose of this article is to examine the Army service of Dr. William H. Welch during World War I. Archival research utilizing prime source documents in the William H. Welch Collection of the Alan M. Chesney Medical Archives for the Johns Hopkins Medical Institutions. Welch joined the Army at the age of 67 after serving as one of the principal transformational forces for reforming medical education in the United States and founding the first academic institution for educating public health professionals in the United States, the Johns Hopkins School of Public Health and Hygiene. His longstanding relationship with Army Surgeon General William Gorgas served as the backdrop for Welch's service. Welch served as both a staff officer and as a traveling medical inspector general, assessing the medical care of troops preparing for overseas duty. He did not adapt particularly well to military dress and decorum but his status as one of the icons of American medicine rendered these shortcomings insignificant. Welch was joined in Army service by a number of American medical luminaries-both Mayo brothers, George Crile, and Harvey Cushing among them. Although Welch remained on active duty for only 13 months, he maintained a nominal relationship with Army medicine through appointment to the Medical Officer Reserve Corps until the time of his death. 2016 marks the centennial of the establishment of the first independent academic institution in America dedicated to education and training of professionals focused on public health and hygiene issues. 2017 marks the centennial of U.S. entry into World War I. Dr. William H. Welch played an important role in both of these historic events and, although his active service was brief, the impact of his example was substantial. Analysis of his military career in its full historical context provides insight into the relationship between academic medicine and military medicine during periods of armed conflict. Reprint & Copyright © 2017

  2. Optimisation of Hidden Markov Model using Baum–Welch algorithm ...

    Indian Academy of Sciences (India)

    s12040-016-0780-0. Optimisation of Hidden Markov Model using. Baum–Welch algorithm for prediction of maximum and minimum temperature over Indian Himalaya. J C Joshi1,∗. , Tankeshwar Kumar2, Sunita Srivastava2 and Divya Sachdeva1.

  3. Optimisation of Hidden Markov Model using Baum–Welch algorithm

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Earth System Science; Volume 126; Issue 1. Optimisation of Hidden Markov Model using Baum–Welch algorithm for prediction of maximum and minimum temperature over Indian Himalaya. J C Joshi Tankeshwar Kumar Sunita Srivastava Divya Sachdeva. Volume 126 Issue 1 February 2017 ...

  4. Study on solitary word based on HMM model and Baum-Welch algorithm

    Directory of Open Access Journals (Sweden)

    Junxia CHEN

    Full Text Available This paper introduces the principle of Hidden Markov Model, which is used to describe the Markov process with unknown parameters, is a probability model to describe the statistical properties of the random process. On this basis, designed a solitary word detection experiment based on HMM model, by optimizing the experimental model, Using Baum-Welch algorithm for training the problem of solving the HMM model, HMM model to estimate the parameters of the λ value is found, in this view of mathematics equivalent to other linear prediction coefficient. This experiment in reducing unnecessary HMM training at the same time, reduced the algorithm complexity. In order to test the effectiveness of the Baum-Welch algorithm, The simulation of experimental data, the results show that the algorithm is effective.

  5. Optimisation of Hidden Markov Model using Baum–Welch algorithm ...

    Indian Academy of Sciences (India)

    new model λ is obtained, which is more likely than model λ, producing observation sequence. O. This process of re-estimation is continued till no improvement in the probability of observation sequence reached. 4. Results and discussion. HMMs have been developed for prediction of maximum and minimum temperatures in ...

  6. Optimisation of Hidden Markov Model using Baum–Welch algorithm ...

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Earth System Science; Volume 126; Issue 1. Optimisation of Hidden Markov ... The present work is a part of development of Hidden Markov Model (HMM) based avalanche forecasting system for Pir-Panjal and Great Himalayan mountain ranges of the Himalaya. In this work, HMMs have been ...

  7. A human neurodevelopmental model for Williams syndrome.

    Science.gov (United States)

    Chailangkarn, Thanathom; Trujillo, Cleber A; Freitas, Beatriz C; Hrvoj-Mihic, Branka; Herai, Roberto H; Yu, Diana X; Brown, Timothy T; Marchetto, Maria C; Bardy, Cedric; McHenry, Lauren; Stefanacci, Lisa; Järvinen, Anna; Searcy, Yvonne M; DeWitt, Michelle; Wong, Wenny; Lai, Philip; Ard, M Colin; Hanson, Kari L; Romero, Sarah; Jacobs, Bob; Dale, Anders M; Dai, Li; Korenberg, Julie R; Gage, Fred H; Bellugi, Ursula; Halgren, Eric; Semendeferi, Katerina; Muotri, Alysson R

    2016-08-18

    Williams syndrome is a genetic neurodevelopmental disorder characterized by an uncommon hypersociability and a mosaic of retained and compromised linguistic and cognitive abilities. Nearly all clinically diagnosed individuals with Williams syndrome lack precisely the same set of genes, with breakpoints in chromosome band 7q11.23 (refs 1-5). The contribution of specific genes to the neuroanatomical and functional alterations, leading to behavioural pathologies in humans, remains largely unexplored. Here we investigate neural progenitor cells and cortical neurons derived from Williams syndrome and typically developing induced pluripotent stem cells. Neural progenitor cells in Williams syndrome have an increased doubling time and apoptosis compared with typically developing neural progenitor cells. Using an individual with atypical Williams syndrome, we narrowed this cellular phenotype to a single gene candidate, frizzled 9 (FZD9). At the neuronal stage, layer V/VI cortical neurons derived from Williams syndrome were characterized by longer total dendrites, increased numbers of spines and synapses, aberrant calcium oscillation and altered network connectivity. Morphometric alterations observed in neurons from Williams syndrome were validated after Golgi staining of post-mortem layer V/VI cortical neurons. This model of human induced pluripotent stem cells fills the current knowledge gap in the cellular biology of Williams syndrome and could lead to further insights into the molecular mechanism underlying the disorder and the human social brain.

  8. A Response to Welch's Review of "Urihi A: A Terra‐Floresta Yanomami"

    Directory of Open Access Journals (Sweden)

    Hein van der Voort

    2010-12-01

    Full Text Available A Response to Welch's Review of Urihi A: A Terra‐Floresta Yanomami. Bruce Albert and William Milliken with Gale Goodwin Gomez. São Paulo: Instituto Socioambiental, 2009. 207 pp., illustrations, tables, bibliography, appendices, index. Paperback ISBN: 978‐85‐85994‐72‐3.

  9. William Klemperer

    Science.gov (United States)

    Herschbach, Dudley

    2018-01-01

    Innovative and versatile, William Klemperer devised both unorthodox experimental tools that enhanced molecular spectroscopy and a theoretical model that elucidated the paradoxical chemistry of cold interstellar clouds.

  10. A Reply to van der Voort's Response to Welch's Review of "Urihi A: A Terra‐ Floresta Yanomami"

    Directory of Open Access Journals (Sweden)

    James R. Welch

    2011-02-01

    Full Text Available A Reply to van der Voort's Response to Welch's Review of Urihi A: A Terra‐ Floresta Yanomami. Bruce Albert and William Milliken with Gale Goodwin Gomez. São Paulo: Instituto Socioambiental, 2009. 207 pp., illustrations, tables, bibliography, appendices, index. Paperback ISBN: 978‐85 85994‐72‐3.

  11. William Stern: An Historical Model of a Generalist.

    Science.gov (United States)

    Frost, Dean; Wesley, Frank

    1988-01-01

    Describes William Stern's professional accomplishments, including pioneering work in educational counseling and contributions to general systems such as Gestalt psychology. Argues that Stern's example supports conclusion that no one scientific method provides single best approach to all questions of psychology, and that interaction between…

  12. Relationship of the Williams-Poulios and Manning-Rosen Potential Energy Models for Diatomic Molecules

    International Nuclear Information System (INIS)

    Jia, Chun-Sheng; Peng, Xiao-Long; Zhang, Lie-Hui; Liang, Guang-Chuan; Tang, Hong-Ming

    2014-01-01

    By employing the dissociation energy and the equilibrium bond length for a diatomic molecule as explicit parameters, we generate an improved form of the Williams-Poulios potential energy model. It is found that the negative Williams-Poulios potential model is equivalent to the Manning-Rosen potential model for diatomic molecules. We observe that the Manning-Rosen potential is superior to the Morse potential in reproducing the interaction potential energy curves for the a 3 Σ + u state of the 6 Li 2 molecule and the X 1 Σ + state of the SiF + molecule. (author)

  13. Uus valem otsustamiseks: 10-10-10 / Jack Welch, Suzy Welch

    Index Scriptorium Estoniae

    Welch, Jack

    2009-01-01

    Juhtimisspetsialistid Jack ja Suzy Welch tutvustavad enda loodud valemit 10-10-10, mis on elu juhtimise tööriist aitamaks langetada raskeid otsuseid, hinnates nende mõju 10 minuti, 10 kuu ja 10 aasta pärast

  14. Williams syndrome

    Science.gov (United States)

    Williams-Beuren syndrome ... Williams syndrome is caused by not having a copy of several genes. It may be passed down in families. ... history of the condition. However, people with Williams syndrome have a 50% chance of passing the disorder ...

  15. Differential equations related to the Williams±Bjerknes tumour model

    Indian Academy of Sciences (India)

    Y n. A computer simulation shows that the solution of the preceding problem provides a good approximation to the Williams±Bjerknes tumour model. We prove that this problem has a unique solution, it is defined on ‰0Y ‡I‰, and, for some specially relevant situations, limt3‡Ipi…t† ˆ 1 Vi P I. 2. The tumour growth model.

  16. Differential equations related to the Williams±Bjerknes tumour model

    Indian Academy of Sciences (India)

    Williams±Bjerknes tumour model for a cancer which spreads through an epithelial basal layer modeled on I & Z2. The solution of this problem is a family p ˆ … pi…t††, where each pi…t† could be considered as an approximation to the probability that the cell situated at i is cancerous at time t. We prove that this problem has ...

  17. Differential Equations Related to the Williams-Bjerknes Tumour Model

    Indian Academy of Sciences (India)

    Bjerknes tumour model for a cancer which spreads through an epithelial basal layer modeled on ⊂ 2. The solution of this problem is a family =(()), where each () could be considered as an approximation to the probability that the ...

  18. Moral Criteria and Character Education: A Reply to Welch

    Science.gov (United States)

    Lapsley, Daniel; Narvaez, Darcia

    2011-01-01

    Most of the views ascribed to us we do not recognise and suggest that several misunderstandings flavour Welch's commentary. We clarify some of our positions here and recommend further collaboration among philosophers and psychologists.

  19. Forman Williams

    Science.gov (United States)

    2001-01-01

    Dr. Forman Williams of the University of California, San Diego. He is principal investigator for Droplet Combustion Experiment (DCE/DCE-2) and High Pressure Combustion of Binary Fuel Sprays experiment.

  20. Empirically based models of oceanographic and biological influences on Pacific Herring recruitment in Prince William Sound

    Science.gov (United States)

    Sewall, Fletcher; Norcross, Brenda; Mueter, Franz; Heintz, Ron

    2018-01-01

    Abundances of small pelagic fish can change dramatically over time and are difficult to forecast, partially due to variable numbers of fish that annually mature and recruit to the spawning population. Recruitment strength of age-3 Pacific Herring (Clupea pallasii) in Prince William Sound, Alaska, is estimated in an age-structured model framework as a function of spawning stock biomass via a Ricker stock-recruitment model, and forecasted using the 10-year median recruitment estimates. However, stock size has little influence on subsequent numbers of recruits. This study evaluated the usefulness of herring recruitment models that incorporate oceanographic and biological variables. Results indicated herring recruitment estimates were significantly improved by modifying the standard Ricker model to include an index of young-of-the-year (YOY) Walleye Pollock (Gadus chalcogrammus) abundance. The positive relationship between herring recruits-per-spawner and YOY pollock abundance has persisted through three decades, including the herring stock crash of the early 1990s. Including sea surface temperature, primary productivity, and additional predator or competitor abundances singly or in combination did not improve model performance. We suggest that synchrony of juvenile herring and pollock survival may be caused by increased abundance of their zooplankton prey, or high juvenile pollock abundance may promote prey switching and satiation of predators. Regardless of the mechanism, the relationship has practical application to herring recruitment forecasting, and serves as an example of incorporating ecosystem components into a stock assessment model.

  1. Characterization and 3D reservoir modelling of fluvial sandstones of the Williams Fork Formation, Rulison Field, Piceance Basin, Colorado, USA

    International Nuclear Information System (INIS)

    Pranter, Matthew J; Vargas, Marielis F; Davis, Thomas L

    2008-01-01

    This study describes the stratigraphic characteristics and distribution of fluvial deposits of the Upper Cretaceous Williams Fork Formation in a portion of Rulison Field and addresses 3D geologic modelling of reservoir sand bodies and their associated connectivity. Fluvial deposits include isolated and stacked point-bar deposits, crevasse splays and overbank (floodplain) mudrock. Within the Williams Fork Formation, the distribution and connectivity of fluvial sandstones significantly impact reservoir productivity and ultimate recovery. The reservoir sandstones are primarily fluvial point-bar deposits interbedded with shales and coals. Because of the lenticular geometry and limited lateral extent of the reservoir sandstones (common apparent widths of ∼500–1000 ft; ∼150–300 m), relatively high well densities (e.g. 10 acre (660 ft; 200 m) spacing) are often required to deplete the reservoir. Heterogeneity of these fluvial deposits includes larger scale stratigraphic variability associated with vertical stacking patterns and structural heterogeneities associated with faults that exhibit lateral and reverse offsets. The discontinuous character of the fluvial sandstones and lack of distinct marker beds in the middle and upper parts of the Williams Fork Formation make correlation between wells tenuous, even at a 10 acre well spacing. Some intervals of thicker and amalgamated sandstones within the middle and upper Williams Fork Formation can be correlated across greater distances. To aid correlation and for 3D reservoir modelling, vertical lithology proportion curves were used to estimate stratigraphic trends and define the stratigraphic zonation within the reservoir interval. Object-based and indicator-based modelling methods have been applied to the same data and results from the models were compared. Results from the 3D modelling indicate that sandstone connectivity increases with net-to-gross ratio and, at lower net-to-gross ratios (<30%), differences exist in

  2. Trophic mass-balance model of Alaska's Prince William Sound ecosystem, for the post-spill period 1994-1996

    International Nuclear Information System (INIS)

    Okey, T.A.; Pauly, D.

    1998-01-01

    The Ecopath modelling approach for the Prince William Sound (PWS) ecosystem was described. The area is the site of the 1989 Exxon Valdez oil spill (EVOS), the largest spill in U.S. history. 36,000 tonnes of crude oil spread throughout the central and southwestern PWS into the Gulf of Alaska and along the Kenai and Alaska Peninsula. The initial effects of the oil spill were catastrophic. The Ecopath modelling approach discussed in this report is aimed at providing a cohesive picture of the PWS ecosystem by constructing a mass-balanced model of food-web interactions and trophic flows using information collected since the EVOS. The model includes all biotic components of the ecosystem and provides a quantitative description of food-web interactions and relationships, as well as energy flows among components. The model can provide an understanding of how ecosystems respond to disturbances, such as oil spills. 216 refs., 74 tabs., 13 figs., 8 appendices

  3. Utilizing "The William Allan Kritsonis Balanced Teeter-Totter Model" as a Means to Cultivate a Legacy of Transformational Leaders in Schools: A National Focus

    Science.gov (United States)

    Jacobs, Karen Dupre

    2007-01-01

    The Kritsonis Teeter-Totter Model, developed by Dr. William Allan Kritsonis, is utilized to cultivate a legacy of transformational leaders in schools throughout the United States. In a time when change in schools is inevitable, the model aides school leaders in better defining their individual role in schools and that of their stakeholders in…

  4. Validation of a Brazilian Portuguese Version of the Walking Estimated-Limitation Calculated by History (WELCH

    Directory of Open Access Journals (Sweden)

    Gabriel Grizzo Cucato

    2015-01-01

    Full Text Available Abstract Background: The Walking Estimated-Limitation Calculated by History (WELCH questionnaire has been proposed to evaluate walking impairment in patients with intermittent claudication (IC, presenting satisfactory psychometric properties. However, a Brazilian Portuguese version of the questionnaire is unavailable, limiting its application in Brazilian patients. Objective: To analyze the psychometric properties of a translated Brazilian Portuguese version of the WELCH in Brazilian patients with IC. Methods: Eighty-four patients with IC participated in the study. After translation and back-translation, carried out by two independent translators, the concurrent validity of the WELCH was analyzed by correlating the questionnaire scores with the walking capacity assessed with the Gardner treadmill test. To determine the reliability of the WELCH, internal consistency and test–retest reliability with a seven-day interval between the two questionnaire applications were calculated. Results: There were significant correlations between the WELCH score and the claudication onset distance (r = 0.64, p = 0.01 and total walking distance (r = 0.61, p = 0.01. The internal consistency was 0.84 and the intraclass correlation coefficient between questionnaire evaluations was 0.84. There were no differences in WELCH scores between the two questionnaire applications. Conclusion: The Brazilian Portuguese version of the WELCH presents adequate validity and reliability indicators, which support its application to Brazilian patients with IC.

  5. Looking around houses: attention to a model when drawing complex shapes in Williams syndrome and typical development.

    Science.gov (United States)

    Hudson, Kerry D; Farran, Emily K

    2013-09-01

    Drawings by individuals with Williams syndrome (WS) typically lack cohesion. The popular hypothesis is that this is a result of excessive focus on local-level detail at the expense of global configuration. In this study, we explored a novel hypothesis that inadequate attention might underpin drawing in WS. WS and typically developing (TD) non-verbal ability matched groups copied and traced a house figure comprised of geometric shapes. The house was presented on a computer screen for 5-s periods and participants pressed a key to re-view the model. Frequency of key-presses indexed the looks to the model. The order that elements were replicated was recorded to assess hierarchisation of elements. If a lack of attention to the model explained poor drawing performance, we expected participants with WS to look less frequently to the model than TD children when copying. If a local-processing preference underpins drawing in WS, more local than global elements would be produced. Results supported the first, but not second hypothesis. The WS group looked to the model infrequently, but global, not local, parts were drawn first, scaffolding local-level details. Both groups adopted a similar order of drawing and tracing of parts, suggesting typical, although delayed strategy-use in the WS group. Additionally both groups drew larger elements of the model before smaller elements, suggested a size-bias when drawing. Copyright © 2013 Elsevier Ltd. All rights reserved.

  6. MyWelch: building an information portal system in a medical library environment.

    Science.gov (United States)

    Zhang, Dongming; Zambrowicz, Caroline; Zhou, Hong; Roderer, Nancy

    2003-01-01

    MyWelch is a medical library portal system that users can use to create customized web sites that reflect their research needs and personal interests. In the MyWelch environment, faculty and students are empowered to take a greater role in identifying their needs and determining their requirements in the electronic environment. The portal system also facilitates interaction among library users and staff.

  7. Predictive modeling of subsurface shoreline oil encounter probability from the Exxon Valdez oil spill in Prince William Sound, Alaska.

    Science.gov (United States)

    Nixon, Zachary; Michel, Jacqueline

    2015-04-07

    To better understand the distribution of remaining lingering subsurface oil residues from the Exxon Valdez oil spill (EVOS) along the shorelines of Prince William Sound (PWS), AK, we revised previous modeling efforts to allow spatially explicit predictions of the distribution of subsurface oil. We used a set of pooled field data and predictor variables stored as Geographic Information Systems (GIS) data to generate calibrated boosted tree models predicting the encounter probability of different categories of subsurface oil. The models demonstrated excellent predictive performance as evaluated by cross-validated performance statistics. While the average encounter probabilities at most shoreline locations are low across western PWS, clusters of shoreline locations with elevated encounter probabilities remain in the northern parts of the PWS, as well as more isolated locations. These results can be applied to estimate the location and amount of remaining oil, evaluate potential ongoing impacts, and guide remediation. This is the first application of quantitative machine-learning based modeling techniques in estimating the likelihood of ongoing, long-term shoreline oil persistence after a major oil spill.

  8. Rapid perfusion quantification using Welch-Satterthwaite approximation and analytical spectral filtering

    Science.gov (United States)

    Krishnan, Karthik; Reddy, Kasireddy V.; Ajani, Bhavya; Yalavarthy, Phaneendra K.

    2017-02-01

    CT and MR perfusion weighted imaging (PWI) enable quantification of perfusion parameters in stroke studies. These parameters are calculated from the residual impulse response function (IRF) based on a physiological model for tissue perfusion. The standard approach for estimating the IRF is deconvolution using oscillatory-limited singular value decomposition (oSVD) or Frequency Domain Deconvolution (FDD). FDD is widely recognized as the fastest approach currently available for deconvolution of CT Perfusion/MR PWI. In this work, three faster methods are proposed. The first is a direct (model based) crude approximation to the final perfusion quantities (Blood flow, Blood volume, Mean Transit Time and Delay) using the Welch-Satterthwaite approximation for gamma fitted concentration time curves (CTC). The second method is a fast accurate deconvolution method, we call Analytical Fourier Filtering (AFF). The third is another fast accurate deconvolution technique using Showalter's method, we call Analytical Showalter's Spectral Filtering (ASSF). Through systematic evaluation on phantom and clinical data, the proposed methods are shown to be computationally more than twice as fast as FDD. The two deconvolution based methods, AFF and ASSF, are also shown to be quantitatively accurate compared to FDD and oSVD.

  9. Prince William Sound, Alaska 8/3 Arc-second MHHW Coastal Digital Elevation Model

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA's National Geophysical Data Center (NGDC) is building high-resolution digital elevation models (DEMs) to support individual coastal States as part of the...

  10. Prince William Sound, Alaska 8 Arc-second MHHW Coastal Digital Elevation Model

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA's National Geophysical Data Center (NGDC) is building high-resolution digital elevation models (DEMs) to support individual coastal States as part of the...

  11. PSD computations using Welch's method. [Power Spectral Density (PSD)

    Energy Technology Data Exchange (ETDEWEB)

    Solomon, Jr, O M

    1991-12-01

    This report describes Welch's method for computing Power Spectral Densities (PSDs). We first describe the bandpass filter method which uses filtering, squaring, and averaging operations to estimate a PSD. Second, we delineate the relationship of Welch's method to the bandpass filter method. Third, the frequency domain signal-to-noise ratio for a sine wave in white noise is derived. This derivation includes the computation of the noise floor due to quantization noise. The signal-to-noise ratio and noise flood depend on the FFT length and window. Fourth, the variance the Welch's PSD is discussed via chi-square random variables and degrees of freedom. This report contains many examples, figures and tables to illustrate the concepts. 26 refs.

  12. William Henry Perkin

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education. William Henry Perkin. Articles written in Resonance – Journal of Science Education. Volume 15 Issue 9 September 2010 pp 856-859 Classics. Dyeing Fabrics · William Henry Perkin · More Details Fulltext PDF ...

  13. A View of War and Soldiering in the Carey Novels of Ronald Welch

    Science.gov (United States)

    Barnes, Clive

    2016-01-01

    Ronald Welch's novels featuring the military adventures of the young men of the Carey family were first published between 1954 and 1976 and have recently been reissued. They were uniquely representative of historical military adventure for children in the Britain of this period; and were the last example of a vigorous century-old genre in…

  14. Negligence 10 Years after Gertz v. Welch. Journalism Monographs Number Ninety-Three.

    Science.gov (United States)

    Hopkins, W. Wat

    The implications and shortcomings of court rulings on negligence in libel laws are explored in this paper. The paper first discusses the particulars of the 1974 landmark "Gertz versus Robert Welch, Inc." United States Supreme Court case, in which the court ruled that private persons as well as public figures would be required to prove…

  15. Alternative solution model for the ternary carbonate system CaCO3 - MgCO3 - FeCO3 - I. A ternary Bragg-Williams ordering model

    Science.gov (United States)

    McSwiggen, P.L.

    1993-01-01

    The minerals of the ternary carbonate system CaCO3 - MgCO3 - FeCO3 represent a complex series of solid solutions and ordering states. An understanding of those complexities requires a solution model that can both duplicate the subsolidus phase relationships and generate correct values for the activities. Such a solution model must account for the changes in the total energy of the system resulting from a change in the ordering state of the individual constituents. Various ordering models have been applied to binary carbonate systems, but no attempts have previously been made to model the ordering in the ternary system. This study derives a new set of equations that allow for the equilibrium degree of order to be calculated for a system involving three cations mixing on two sites, as in the case of the ternary carbonates. The method is based on the Bragg-Williams approach. From the degree of order, the mole fractions of the three cations in each of the two sites can be determined. Once the site occupancies have been established, a Margules-type mixing model can be used to determine the free energy of mixing in the solid solution and therefore the activities of the various components. ?? 1993 Springer-Verlag.

  16. David Owen WILLIAMS

    CERN Multimedia

    2006-01-01

    Lidy Williams-Oonk and her children Mark & Marietta, being unable to thank everybody individually, would like to express their sincere thanks to friends and colleagues at CERN and abroad for their great help and support, their messages and flowers, as well as their donations to the Ligue Genevoise contre le Cancer, on the death of their beloved husband and father.

  17. Interaction with William Carnall

    International Nuclear Information System (INIS)

    Judd, Brian R.

    2005-01-01

    A personal account is given of interaction with William T. Carnall during the period 1977-1988, when I made regular visits to the Argonne National Laboratory to discuss the theoretical background to the spectroscopic work he was carrying out on the lanthanides and actinides

  18. Series, Prof. George William

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1984 Honorary. Series, Prof. George William. Date of birth: 22 February 1920. Date of death: 2 January 1995. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. 29th Mid-year meeting. Posted on 19 January 2018. The 29th Mid-year meeting of the Academy will be held ...

  19. Bragg, Prof. William Henry

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1935 Honorary. Bragg, Prof. William Henry Nobel Laureate (Physics) - 1915. Date of birth: 2 July 1862. Date of death: 10 March 1972. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. 29th Mid-year meeting. Posted on 19 January 2018. The 29th Mid-year meeting of ...

  20. Florence Jessie Mac Williams

    Indian Academy of Sciences (India)

    CPMGIKAlBGE-340/2003-05. Resonance - January 2005. Licenced to post WPP No.6 RT Nagar Postoffice. Florence Jessie Mac Williams. (1917 - 1990). Registered with Registrar of Newspapers in India vide Regn. No. 66273/96. ISSN 0971-8044. Price per copy: Rs 40.

  1. William Donald Hamilton

    Indian Academy of Sciences (India)

    Page 1. CPMGlKAlBGE-34OI2001. Licenced to post WPP(E) No.6. Resonance - April 2001. William Donald Hamilton. (1936 - 2000). Registered with Registrar of Newspapers in India vide Regn. No. 66273/96. ISSN 0971-8044.

  2. Anderson, Prof. Basil Williams

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1964 Honorary. Anderson, Prof. Basil Williams. Date of birth: 3 July 1901. Date of death: 24 February 1984. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. 29th Mid-year meeting. Posted on 19 January 2018. The 29th Mid-year meeting of the Academy will be held ...

  3. William L Griffin

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Earth System Science. William L Griffin. Articles written in Journal of Earth System Science. Volume 126 Issue 8 December 2017 pp 107. Formation of atoll garnets in the UHP eclogites of the Tso Morari Complex, Ladakh, Himalaya · Mallika K Jonnalagadda Nitin R Karmalkar Raymond A ...

  4. C W Williams

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education. C W Williams. Articles written in Resonance – Journal of Science Education. Volume 19 Issue 8 August 2014 pp 704-712 General Article. Do Identical Polar Diatomic Molecules Form Stacked or Linear Dimers?: Hydrogen Bonding is Not Just Dipole-Dipole ...

  5. Bridgman, Prof. Percy Williams

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1952 Honorary. Bridgman, Prof. Percy Williams Nobel Laureate (Physics) - 1946. Date of birth: 21 April 1882. Date of death: 20 August 1961. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the ...

  6. Anderson, Prof. Basil Williams

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1964 Honorary. Anderson, Prof. Basil Williams. Date of birth: 3 July 1901. Date of death: 24 February 1984. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three Science Academies of India on ...

  7. Sir William Rowan Hamilton

    Indian Academy of Sciences (India)

    IAS Admin

    Against the background of the development of physics, and in particular of mechanics, over the centuries since Galileo and Newton, we describe the life and work of William Rowan Hamilton in the 19th century. The depth of his ideas which brought together the understanding of ray op- tics and classical mechanics, and the ...

  8. Bragg, Prof. William Henry

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1935 Honorary. Bragg, Prof. William Henry Nobel Laureate (Physics) - 1915. Date of birth: 2 July 1862. Date of death: 10 March 1972. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three ...

  9. Series, Prof. George William

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1984 Honorary. Series, Prof. George William. Date of birth: 22 February 1920. Date of death: 2 January 1995. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three Science Academies of India ...

  10. [Architecture of the X chromosome, expression of LIM kinase 1, and recombination in the agnostic mutants of Drosophila: a model of human Williams syndrome].

    Science.gov (United States)

    Savvateeva-Popova, E V; Peresleni, A I; Sharagina, L M; Medvedeva, A V; Korochkina, S E; Grigor'eva, I V; Diuzhikova, N A; Popov, A V; Baricheva, E M; Karagodin, D; Heisenberg, M

    2004-06-01

    As the Human Genome and Drosophila Genome Projects were completed, it became clear that functions of human disease-associated genes may be elucidated by studying the phenotypic expression of mutations affecting their structural or functional homologs in Drosophila. Genomic diseases were identified as a new class of human disorders. Their cause is recombination, which takes place at gene-flanking duplicons to generate chromosome aberrations such as deletions, duplications, inversions, and translocations. The resulting imbalance of the dosage of developmentally important genes arises at a frequency of 10(-3) (higher than the mutation rate of individual genes) and leads to syndromes with multiple manifestations, including cognitive defects. Genomic DNA fragments were cloned from the Drosophila melanogaster agnostic locus, whose mutations impair learning ability and memory. As a result, the locus was exactly localized in X-chromosome region 11A containing the LIM kinase 1 (LIMK1) gene (CG1848), which is conserved among many species. Hemizygosity for the LIMK1 gene, which is caused by recombination at neighboring extended repeats, underlies cognitive disorders in human Williams syndrome. LIMK1 is a component of the integrin signaling cascade, which regulates the functions of the actin cytoskeleton, synaptogenesis, and morphogenesis in the developing brain. Immunofluorescence analysis revealed LIMK1 in all subdomains of the central complex and the visual system of Drosophila melanogaster. Like in the human genome, the D. melanogaster region is flanked by numerous repeats, which were detected by molecular genetic methods and analysis of ectopic chromosome pairing. The repeats determined a higher rate of spontaneous and induced recombination. including unequal crossing over, in the agnostic gene region. Hence, the agnostic locus was considered as the first D. melanogaster model suitable for studying the genetic defect associated with Williams syndrome in human.

  11. William D. Hamilton's Brazilian lectures and his unpublished model regarding Wynne-Edwards's idea of natural selection. With a note on 'pluralism' and different philosophical approaches to evolution.

    Science.gov (United States)

    Coco, Emanuele

    2016-12-01

    In 1975, the English evolutionist William Donald Hamilton (1936-2000) held in Brazil a series of lectures entitled "Population genetics and social behaviour". The unpublished notes of these conferences-written by Hamilton and recently discovered at the British Library-offer an opportunity to reflect on some of the author's ideas about evolution. The year of the conference is particularly significant, as it took place shortly after the applications of the Price equation with which Hamilton was able to build a model that included several levels of selection. In this paper I mainly analyse the inaugural lecture in which Hamilton proposes a simple model to disprove the hypothesis supported by the British zoologist C. Vero Wynne-Edwards (1906-1997) regarding mechanisms to prevent "over-exploitation of the food supply" in "the interests of the survival of the group". The document presented here is of great historical interest. Not only because manuscript offers a model that-since it was intended for teaching purposes-had never before appeared in the published version, but also because of the general index of the lectures that accompanies it. The latter allows us to make some hypothetical considerations on the relationship and differences between kin-selection, group-selection and inclusive fitness that Hamilton wanted to present to the attentive, well-prepared audience of the foreign university that had invited him.

  12. [Sir William Osler's legacy].

    Science.gov (United States)

    Chrobák, Ladislav

    2004-01-01

    William Osler (1849-1919) is generally regarded as one of the greatest and most respected physicians in the history of medicine. As an outstanding clinician and a professor of medicine at four universities in three countries he exerted a profound influence on medical education. His textbook "The Principles and Practice of Medicine" became the most popular treatise on medicine in the world. He emphasized the value of hard work. His compassion and concern for patients, students and colleagues reflected his personality. Osler's humanism, his philosophy and views did not lose their validity even today.

  13. Whither Sir William?

    Directory of Open Access Journals (Sweden)

    Stephen J. Greenberg, MSLS, PhD

    2017-04-01

    Full Text Available There are times when something is simply so familiar that we can no longer see it at all. It can be a story, or a concept, or even a flesh-and-blood person. Familiarity breeds not only contempt, but a kind of invisibility as well. For too many of us, such is the case with Sir William Osler. In his time (1849–1919, many considered him to be one of the greatest practitioners, teachers, and writers ever in the field of medicine. He was instrumental in the founding of the Medical Library Association (MLA and was elected its second president.

  14. Genetics Home Reference: Williams syndrome

    Science.gov (United States)

    ... CA, Berman KF. Neural correlates of genetically abnormal social cognition in Williams syndrome. Nat Neurosci. 2005 Aug;8(8):991-3. Epub 2005 Jul 10. Citation on PubMed Meyer-Lindenberg A, Mervis CB, Berman KF. Neural mechanisms in Williams syndrome: a unique window to genetic ...

  15. Improved Weizsaecker-Williams method

    International Nuclear Information System (INIS)

    Olsen, H.A.

    1978-01-01

    In the spirit of the Weizsaecker-Williams method virtual photon spectra are derived which have the Weizsaecker-Williams form for low frequencies. It is shown that for the cases of pair production of fermions and single boson production the photon spectra give remarkably accurate results for one and two virtual photon processes. (Auth.)

  16. Improved Weizsaecker-Williams method

    International Nuclear Information System (INIS)

    Olsen, H.A.

    1979-01-01

    In the spirit of the Weizsaecker-Williams method virtual-photon spectra are derived which have the Weizsaecker-Williams form for low frequencies. It is shown for the cases of pair production of fermions and single-boson production that the photon spectra give remarkably accurate results for one- and two-virtual-photon processes

  17. William Herschel and Comets

    Science.gov (United States)

    Sullivan, Woodruff

    2018-01-01

    I examine the observational and theoretical researches of William Herschel on 21 comets that he observed over the period 1781 to 1812. Herschel's focus, unlike most contemporaries, was on their physical structure, not their orbits. He forged a strong connection between comets and his nebulae with a scheme of cometary "maturation" (1812) involved a comet traveling from star to star after its central "planetary body'; was born from gravitational collapse of a nebula. During close passages of a star, the comet brightened and lost mass from its atmosphere; at other times, when between stars, it encountered nebulae and was rejuvenated by picking up more mass. Laplace soon adopted these ideas to improve his nebula hypothesis for solar system formation.

  18. Community, Labour and Raymond Williams.

    Science.gov (United States)

    McIlroy, John

    1993-01-01

    Raymond Williams, a British adult educator, believed that community must be at the heart of education and that education must involve the primary organizations of the working class, such as trade unions, to be effective. (SK)

  19. Watermark Compression in Medical Image Watermarking Using Lempel-Ziv-Welch (LZW) Lossless Compression Technique.

    Science.gov (United States)

    Badshah, Gran; Liew, Siau-Chuin; Zain, Jasni Mohd; Ali, Mushtaq

    2016-04-01

    In teleradiology, image contents may be altered due to noisy communication channels and hacker manipulation. Medical image data is very sensitive and can not tolerate any illegal change. Illegally changed image-based analysis could result in wrong medical decision. Digital watermarking technique can be used to authenticate images and detect as well as recover illegal changes made to teleradiology images. Watermarking of medical images with heavy payload watermarks causes image perceptual degradation. The image perceptual degradation directly affects medical diagnosis. To maintain the image perceptual and diagnostic qualities standard during watermarking, the watermark should be lossless compressed. This paper focuses on watermarking of ultrasound medical images with Lempel-Ziv-Welch (LZW) lossless-compressed watermarks. The watermark lossless compression reduces watermark payload without data loss. In this research work, watermark is the combination of defined region of interest (ROI) and image watermarking secret key. The performance of the LZW compression technique was compared with other conventional compression methods based on compression ratio. LZW was found better and used for watermark lossless compression in ultrasound medical images watermarking. Tabulated results show the watermark bits reduction, image watermarking with effective tamper detection and lossless recovery.

  20. William Rowan Hamilton: Mathematical genius

    Energy Technology Data Exchange (ETDEWEB)

    Wilkins, D.R. [School of Mathematics, Trinity College, Dublin (Ireland)]. E-mail: dwilkins@maths.tcd.ie

    2005-08-01

    This year Ireland celebrates the bicentenary of the mathematician William Rowan Hamilton, best remembered for 'quaternions' and for his pioneering work on optics and dynamics. Two centuries after his birth, the extent to which terms such as 'Hamiltonian' and 'Hamiltonian system' have entered the everyday language of mathematicians and physicists testifies to the continuing impact of the scientific work of William Rowan Hamilton. (U.K.)

  1. "Don't you realize it's Just Her Disguise?" : Performances of femininity by Kim Gordon, Tori Amos and Gillian Welch

    OpenAIRE

    Håkensen, Siv Tonje

    2007-01-01

    Women who perform popular music are also performing gender. This is both because gender can be understood as performance and because musical conventions and styles carry with them assumptions about femininity and masculinity. This thesis concerns three female popular music artists; Kim Gordon of Sonic Youth, Tori Amos and Gillian Welch, and their performances of femininity. As these artists have been presented as or have presented themselves as in some way "authentic", my readings of these ar...

  2. 76 FR 22363 - Kaibab National Forest, Williams Ranger District; Arizona; Bill Williams Mountain Restoration...

    Science.gov (United States)

    2011-04-21

    ... DEPARTMENT OF AGRICULTURE Forest Service Kaibab National Forest, Williams Ranger District; Arizona; Bill Williams Mountain Restoration Project AGENCY: Forest Service, USDA. ACTION: Notice of intent to... health and sustainability of forested conditions on and surrounding Bill Williams Mountain by reducing...

  3. [Williams-Beuren syndrome (Williams syndrome). Case report].

    Science.gov (United States)

    Miklós, Györgyi; Fekete, György; Haltrich, Irén; Tóth, Miklós; Reismann, Péter

    2017-11-01

    Williams syndrome is a rare genetic disorder, that occurs equally in all ethnic groups and both sexes. The diagnosis might be missed during childhood in mild cases. However, establishing the diagnosis is important, not only to find the cause of intellectual disability but to look for cardiovascular, endocrine, psychiatry, urology and other conditions, which can occur at any age in the patients' lifetime. This case report presents the story of 47-year-old woman, who was admitted with haematemesis. During her stay on the ward, in the light of the distinctive facial features, mental retardation, and social behaviour patterns, the possibility of Williams syndrome emerged. Later, the diagnosis was confirmed by genetic analysis. This female is the oldest living patient with Williams syndrome in Hungary. Orv Hetil. 2017; 158(47): 1883-1888.

  4. Interview: William and Barbara Christopher.

    Science.gov (United States)

    Teaching Exceptional Children, 1986

    1986-01-01

    Asserting that the biggest mistake educators can make is to set themselves up as experts vis-a-vis parents as amateurs, Barbara and William Christopher emphasize the importance of continued education for the autistic individual and relate their experiences with the educational community as they sought help for their autistic son. (JC)

  5. Aderemi-Williams, R I

    African Journals Online (AJOL)

    Aderemi-Williams, R I. Vol 17, No 4 (2007) - Articles Community Pharmacies As Possible Centres For Routine Immunization Abstract. ISSN: 0189-2657. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of ...

  6. Skin findings in Williams syndrome.

    Science.gov (United States)

    Kozel, Beth A; Bayliss, Susan J; Berk, David R; Waxler, Jessica L; Knutsen, Russell H; Danback, Joshua R; Pober, Barbara R

    2014-09-01

    Previous examination in a small number of individuals with Williams syndrome (also referred to as Williams-Beuren syndrome) has shown subtly softer skin and reduced deposition of elastin, an elastic matrix protein important in tissue recoil. No quantitative information about skin elasticity in individuals with Williams syndrome is available; nor has there been a complete report of dermatologic findings in this population. To fill this knowledge gap, 94 patients with Williams syndrome aged 7-50 years were recruited as part of the skin and vascular elasticity (WS-SAVE) study. They underwent either a clinical dermatologic assessment by trained dermatologists (2010 WSA family meeting) or measurement of biomechanical properties of the skin with the DermaLab™ suction cup (2012 WSA family meeting). Clinical assessment confirmed that soft skin is common in this population (83%), as is premature graying of the hair (80% of those 20 years or older), while wrinkles (92%), and abnormal scarring (33%) were detected in larger than expected proportions. Biomechanical studies detected statistically significant differences in dP (the pressure required to lift the skin), dT (the time required to raise the skin through a prescribed gradient), VE (viscoelasticity), and E (Young's modulus) relative to matched controls. The RT (retraction time) also trended longer but was not significant. The biomechanical differences noted in these patients did not correlate with the presence of vascular defects also attributable to elastin insufficiency (vascular stiffness, hypertension, and arterial stenosis) suggesting the presence of tissue specific modifiers that modulate the impact of elastin insufficiency in each tissue. © 2014 Wiley Periodicals, Inc.

  7. Stretching Exercises: Range of Motion and Emotion in Four Poems by William Carlos Williams.

    Science.gov (United States)

    Lenhart, Gary

    1998-01-01

    Discusses four poems by William Carlos Williams used to teach creative writing to college students. Uses "Portrait of a Woman in Red" and "The Last Words of My English Grandmother" because they contain speakers who are clearly not the poet, which gives undergraduate students opportunities to discuss details Williams uses to…

  8. Tidens Rytmik. Dante Alighieri, William Carlos Williams' Prosodi og Michel Serres

    DEFF Research Database (Denmark)

    Stougaard-Nielsen, Jakob

    2006-01-01

      Artiklen diskuterer William Carlos Williams' poetik og hans lyriske eksperimenter i tilknytning til begreberne 'den variable fod' og 'det triadiske vers'. Den argumenterer for, at Williams' poetik kan opfattes både som et forsøg på at vitalisere et typografisk styret poetisk  sprog og som del af...

  9. The Third Turn toward the Social: Nancy Welch's "Living Room," Tony Scott's "Dangerous Writing," and Rhetoric and Composition's Turn toward Grassroots Political Activism

    Science.gov (United States)

    Kinney, Kelly; Girshin, Thomas; Bowlin, Barrett

    2013-01-01

    This review essay examines recent texts by Nancy Welch and Tony Scott, both of which use embodied activism as a starting point for their inquiries. Taken together, these works point to a distinct shift in composition studies' turn toward the social, one that calls on workers both within and outside the academy to actively engage in grassroots…

  10. William Wilde: his contribution to otology.

    Science.gov (United States)

    Walsh, M

    2016-05-01

    Sir William Wilde pioneered the epidemiology of deafness. He set otology on a firm scientific basis by applying the principles established by Robert Graves and William Stokes of the Dublin School of Medicine of correlating clinical observation with post-mortem findings and utilising this information as a framework for therapeutic intervention.

  11. William Russell on Schools in Bulgaria

    Science.gov (United States)

    Popov, Nikolay; Sabic-El-Rayess, Amra

    2013-01-01

    William Russell became one of the most influential educators in the field of international and comparative education in the first half of the 20th century. In 1914, William Russell obtained his PhD from Teachers College and, within few years, became a prominent figure internationally. He traveled through Europe and taught in Japan and Siberia, as…

  12. Williams syndrome starts making sense

    Energy Technology Data Exchange (ETDEWEB)

    Ashkenas, J.

    1996-10-01

    1996 may be marked as a transitional year in the study of Williams syndrome (WS), when the causes of this complex condition and a practical way to investigate began to come into focus. WS presents a remarkable collection of symptoms that affect blood vessels, growth, intelligence, and behavior. WS commonly leads to infantile hypercalcemia, retardation of growth, prematurely wrinkled skin, supraventricular aortic stenosis (SVAS), and sensitivity to loud noise. Children with this condition are often mentally retarded, with distinctive {open_quotes}elfin{close_quotes} facial features, a hoarse voice, and an {open_quotes}engaging{close_quotes} personality. Their cognitive deficits may be minimal or profound but typically involve a specific pattern of strengths and weaknesses, with better-than-average face recognition but little ability to recognize how parts of patterns that they see fit into a whole. 36 refs.

  13. Seasonal distribution of Dall's porpoise in Prince William Sound, Alaska

    Science.gov (United States)

    Moran, John R.; O'Dell, Matthew B.; Arimitsu, Mayumi L.; Straley, Janice M.; Dickson, Danielle M. S.

    2018-01-01

    Dall's porpoise, Phocoenoides dalli, are a conspicuous predator in the Prince William Sound ecosystem, yet there has been little effort directed towards monitoring this species since the 1980s, prior to the Exxon Valdez oil spill. We used vessel-based surveys to examine the seasonal distribution of Dall's porpoise in the waters of Prince William Sound during eight years from 2007 to 2015. Over the course of 168 days and 15,653 km of survey effort, 921 Dall's porpoise were encountered in 210 groups. We estimate an encounter rate of 0.061 porpoise/km traveled or 1 porpoise encountered for every 16.5 km traveled. Dall's porpoise were found throughout the year in Prince William Sound, and used a wide range of habitats, including those not considered typical of the species, such as bays, shallow water, and nearshore waters. Dall's porpoise seasonally shifted their center of distribution from the western passages in fall to the bays of the eastern Sound in winter and spring. Dall's porpoises were widely dispersed throughout the Sound in summer. We identified potential Dall's porpoise habitat (depth, slope, and distance from shore) within Prince William Sound using generalized additive models (GAM). Dall's porpoise were found in deeper water during summer and in shallowest water during spring. We propose that their use of novel habitats is a function of reduced predation risk associated with the decline of their main predator, killer whales (Orcinus orca), following the Exxon Valdez oil spill, and the presence of overwintering and spawning Pacific herring (Clupea pallasii). While the size of the Dall's porpoise population within Prince William Sound remains unknown, our encounter rates were lower than those reported in the 1970s. Their high metabolic rate and ubiquitous presence makes them one of the more important, yet understudied, forage fish predators in the region.

  14. STS-101: Crew Interview / Jeffrey N. Williams

    Science.gov (United States)

    2000-01-01

    Live footage of a preflight interview with Mission Specialist Jeffrey N. Williams is seen. The interview addresses many different questions including why Williams became an astronaut, and the events that led to his interest. Other interesting information that this one-on-one interview discusses is his reaction to and the reasons for the change of the mission objectives. Williams also mentions the scheduled space-walk that he will perform, docking with the International Space Station (ISS), the repairs of equipment, and the change of the batteries.

  15. Generalized Bragg-Williams method for 'antiferromagnetic' lattice gases

    International Nuclear Information System (INIS)

    Osorio, R.

    1983-01-01

    The many-sublattice Bragg-Williams approximation of statistical mechanics is applied to the two-dimensional square and triangular lattice-gas models with nearest-neighbor repulsive interactions. Each problem is solved through both the canonical and grand-canonical methods. The present treatment emphasizes the duality between concentration and chemical potential and illustrates the appearance of first- and second -order transitions in each method. (Author) [pt

  16. William Band at Yenching University

    Science.gov (United States)

    Hu, Danian

    2008-04-01

    William Band (1906-1993) has been widely remembered by his American colleagues and students as ``a fine physicist and teacher,'' who taught at Washington State University in Pullman between 1949 and 1971 and authored Introduction to Quantum Statistics (1954) and Introduction to Mathematical Physics (1959). Not many, however, knew much about Band's early career, which was very ``uncommon and eventful.'' Born in England, Band graduated from University of Liverpool in 1927 with an MsSc degree in physics. Instead of pursuing his Ph.D. at Cambridge, he chose to teach physics at Yenching University, a prestigious Christian university in Beijing, China. Arriving in 1929, Band established his career at Yenching, where he taught and researched the theory of relativity and quantum mechanics, pioneered the study on low-temperature superconductivity in China, founded the country's first graduate program in physics, and chaired the Physics Department for 10 years until he fled from Yenching upon hearing of the attack on Pearl Harbor. It took him two years to cross Japanese occupied areas under the escort of the Communist force; he left China in early 1945. This presentation will explore Band's motivation to work in China and his contributions to the Chinese physics research and education.

  17. David Owen Williams (1944 - 2006)

    CERN Document Server

    2006-01-01

    Many people, not only at CERN but also throughout the world, were saddened to learn that their friend and colleague David Williams had passed away in the early hours of Tuesday 24 October. His death came after a year of fighting cancer with all of his usual determination and optimism. Even days before the end he was still welcoming to visitors, and was alert and interested in all their news. Born in 1944, David came to CERN from the University of Cambridge in 1966, with a degree in Physics and Computer Science. Joining what at the time was called the Documents and Data (DD) Division, in the earlier part his career he worked first on software for analysis of bubble chamber photographs, subsequently leading the group that supported experiments with 'hybrids' of bubble chambers and electronic detectors and then the group supporting online computing in experiments. He thus witnessed all of the enormous changes that took place in particle physics as the era of bubble chambers came to an end and the availability ...

  18. William Harvey, Aristotle and astrology.

    Science.gov (United States)

    Gregory, Andrew

    2014-06-01

    In this paper I argue that William Harvey believed in a form of astrology. It has long been known that Harvey employed a macrocosm-microcosm analogy and used alchemical terminology in describing how the two types of blood change into one another. This paper then seeks to examine a further aspect of Harvey in relation to the magical tradition. There is an important corollary to this line of thought, however. This is that while Harvey does have a belief in astrology, it is strongly related to Aristotle's views in this area and is quite restricted and attenuated relative to some contemporary beliefs in astrology. This suggests a more general thesis. While Harvey was amenable to ideas which we associate with the natural magic tradition, those ideas had a very broad range of formulation and there was a limit to how far he would accept them. This limit was largely determined by Harvey's adherence to Aristotle's natural philosophy and his Christian beliefs. I argue that this is also the case in relation to Harvey's use of the macrocosm-microcosm analogy and of alchemical terminology, and, as far as we can rely on the evidence, this informs his attitudes towards witches as well. Understanding Harvey's influences and motives here is important in placing him properly in the context of early seventeenth-century thought.

  19. William Paley's lost "intelligent design".

    Science.gov (United States)

    Shapiro, Adam R

    2009-01-01

    William Paley's Natural Theology has experienced a resurgence in popularity in recent decades with the continuing controversies over the teaching of evolution and the emergence of a new "intelligent design" movement. But while both the movement's supporters and detractors agree that Paley is an intellectual forefather of the present-day movement, this agreement is forged at the expense of historical accuracy. Paley's intelligent design has almost nothing in common with the present day movement and, in fact, suggests theological arguments against the type of reasoning used by the modern movement. Paley wrote in reaction to Hume and in response to the evolutionary theories of Buffon and Erasmus Darwin. In this light, the Natural Theology suggests a different reading than it is usually given. Paley's narrowly-argued theology relies upon the ability to detect the presence of "purpose" in nature without relying upon knowing what those purposes are. His empirically-argued theology leads him to a God who operates through natural law, not in its contravention, and his concern goes far beyond proving the existence of a deity to undertaking the theological project of determining the attributes and characteristics of the deity. Though not himself an evolutionist, Paley put forth a theological worldview consistent with evolution. In fact, given his arguments that the observation of great contrivance increases the testimony of nature to God's power, Paley's philosophy might be more consistent with a theistic Darwinian evolution than with special creation.

  20. William Friedman, Geneticist Turned Cryptographer.

    Science.gov (United States)

    Goldman, Irwin L

    2017-05-01

    William Friedman (1891-1969), trained as a plant geneticist at Cornell University, was employed at Riverbank Laboratories by the eccentric millionaire George Fabyan to work on wheat breeding. Friedman, however, soon became intrigued by and started working on a pet project of Fabyan's involving the conjecture that Francis Bacon, a polymath known for the study of ciphers, was the real author of Shakespeare's plays. Thus, beginning in ∼1916, Friedman turned his attention to the so called "Baconian cipher," and developed decryption techniques that bore similarity to approaches for solving problems in population genetics. His most significant, indeed pathbreaking, work used ideas from genetics and statistics, focusing on analysis of the frequencies of letters in language use. Although he had transitioned from being a geneticist to a cryptographer, his earlier work had resonance in his later pursuits. He soon began working directly for the United States government and produced solutions used to solve complex military ciphers, in particular to break the Japanese Purple code during World War II. Another important legacy of his work was the establishment of the Signal Intelligence Service and eventually the National Security Agency. Copyright © 2017 by the Genetics Society of America.

  1. Prince William Sound, Alaska ESI: INDEX

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set comprises the Environmental Sensitivity Index (ESI) data for Prince William Sound, Alaska. ESI data characterize estuarine environments and wildlife by...

  2. Prince William Sound, Alaska ESI: HYDRO (Hydrology)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set comprises the Environmental Sensitivity Index (ESI) data for Prince William Sound, Alaska. ESI data characterize estuarine environments and wildlife by...

  3. Prince William Sound, Alaska ESI: INVERT (Invertebrates)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set comprises the Environmental Sensitivity Index (ESI) data for Prince William Sound, Alaska. ESI data characterize estuarine environments and wildlife by...

  4. The Representation of Tropical Cyclones Within the Global William Putman Non-Hydrostatic Goddard Earth Observing System Model (GEOS-5) at Cloud-Permitting Resolutions

    Science.gov (United States)

    Putman, William M.

    2010-01-01

    The Goddard Earth Observing System Model (GEOS-S), an earth system model developed in the NASA Global Modeling and Assimilation Office (GMAO), has integrated the non-hydrostatic finite-volume dynamical core on the cubed-sphere grid. The extension to a non-hydrostatic dynamical framework and the quasi-uniform cubed-sphere geometry permits the efficient exploration of global weather and climate modeling at cloud permitting resolutions of 10- to 4-km on today's high performance computing platforms. We have explored a series of incremental increases in global resolution with GEOS-S from irs standard 72-level 27-km resolution (approx.5.5 million cells covering the globe from the surface to 0.1 hPa) down to 3.5-km (approx. 3.6 billion cells).

  5. Kuumalaine / Craig Welch

    Index Scriptorium Estoniae

    Welch, Craig

    2016-01-01

    Al. 2013. a. talvest ei suutnud nõrgad tuuled Vaikse ookeani kirdeosa vett jahutada. Soojus levis piki Vaikse ookeani rannikut 2015. a. lõpuni, paigutades ümber mereelustikku, ajades sassi toiduvõrgustiku ning põhjustades suure mürgise vetikavohangu

  6. Modeling Behavior by Coastal River Otter (Lontra Canadensis in Response to Prey Availability in Prince William Sound, Alaska: A Spatially-Explicit Individual-Based Approach.

    Directory of Open Access Journals (Sweden)

    Shannon E Albeke

    Full Text Available Effects of climate change on animal behavior and cascading ecosystem responses are rarely evaluated. In coastal Alaska, social river otters (Lontra Canadensis, largely males, cooperatively forage on schooling fish and use latrine sites to communicate group associations and dominance. Conversely, solitary otters, mainly females, feed on intertidal-demersal fish and display mutual avoidance via scent marking. This behavioral variability creates "hotspots" of nutrient deposition and affects plant productivity and diversity on the terrestrial landscape. Because the abundance of schooling pelagic fish is predicted to decline with climate change, we developed a spatially-explicit individual-based model (IBM of otter behavior and tested six scenarios based on potential shifts to distribution patterns of schooling fish. Emergent patterns from the IBM closely mimicked observed otter behavior and landscape use in the absence of explicit rules of intraspecific attraction or repulsion. Model results were most sensitive to rules regarding spatial memory and activity state following an encounter with a fish school. With declining availability of schooling fish, the number of social groups and the time simulated otters spent in the company of conspecifics declined. Concurrently, model results suggested an elevation of defecation rate, a 25% increase in nitrogen transport to the terrestrial landscape, and significant changes to the spatial distribution of "hotspots" with declines in schooling fish availability. However, reductions in availability of schooling fish could lead to declines in otter density over time.

  7. College Fjord, Prince Williams Sound

    Science.gov (United States)

    2000-01-01

    The College Fjord with its glaciers was imaged by ASTER on June 24, 2000.This image covers an area 20 kilometers (13 miles) wide and 24 kilometers (15 miles) long in three bands of the reflected visible and infrared wavelength region. College Fjord is located in Prince Williams Sound, east of Seward, Alaska. Vegetation is in red, and snow and ice are white and blue. Ice bergs calved off of the glaciers can be seen as white dots in the water. At the head of the fjord, Harvard Glacier (left) is one of the few advancing glaciers in the area; dark streaks on the glacier are medial moraines: rock and dirt that indicate the incorporated margins of merging glaciers. Yale Glacier to the right is retreating, exposing (now vegetated) bedrock where once there was ice. On the west edge of the fjord, several small glaciers enter the water. This fjord is a favorite stop for cruise ships plying Alaska's inland passage.This image is located at 61.2 degrees north latitude and 147.7 degrees west longitude. Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) is one of five Earth-observing instruments launched December 18, 1999, on NASA's Terra satellite. The instrument was built by Japan's Ministry of International Trade and Industry. A joint U.S./Japan science team is responsible for validation and calibration of the instrument and the data products. Dr. Anne Kahle at NASA's Jet Propulsion Laboratory, Pasadena, Calif., is the U.S. Science team leader; Moshe Pniel of JPL is the project manager. ASTER is the only high resolution imaging sensor on Terra. The primary goal of the ASTER mission is to obtain high-resolution image data in 14 channels over the entire land surface, as well as black and white stereo images. With revisit time of between 4 and 16 days, ASTER will provide the capability for repeat coverage of changing areas on Earth's surface.The broad spectral coverage and high spectral resolution of ASTER will provide scientists in numerous disciplines with

  8. Robin Williams' suicide: a case study

    Directory of Open Access Journals (Sweden)

    Hassaan Tohid

    Full Text Available Abstract Introduction: The world renowned comedian and four-time Oscar nominated actor Robin Williams died on August 11, 2014. From the outset, the news indicated that his death was believed to be a suicide and this was later confirmed to be true by the autopsy reports. Williams had been suffering from severe depression, which is believed to be the leading contributor to his suicide. In this case study, I will highlight the event of the actor's suicide and the main risk factors along with depression leading to his tragic death. As of the end of 2015, no other case study seemed to have addressed or explored the links between the cause (or causes and events leading to Robin Williams' suicide. Case description: Robin Williams was suffering from relationship problems, financial problems, drug addiction, and major depression. All of these factors led to his suicide. Comments: The chances of committing suicide drastically increase in the presence of any of the key risk factors. Unfortunately, the actor Robin Williams was dealing with four of the major risk factors all together, which put him at a high risk of committing suicide and eventually led to his tragic death.

  9. Robin Williams' suicide: a case study.

    Science.gov (United States)

    Tohid, Hassaan

    2016-01-01

    The world renowned comedian and four-time Oscar nominated actor Robin Williams died on August 11, 2014. From the outset, the news indicated that his death was believed to be a suicide and this was later confirmed to be true by the autopsy reports. Williams had been suffering from severe depression, which is believed to be the leading contributor to his suicide. In this case study, I will highlight the event of the actor's suicide and the main risk factors along with depression leading to his tragic death. As of the end of 2015, no other case study seemed to have addressed or explored the links between the cause (or causes) and events leading to Robin Williams' suicide. Robin Williams was suffering from relationship problems, financial problems, drug addiction, and major depression. All of these factors led to his suicide. The chances of committing suicide drastically increase in the presence of any of the key risk factors. Unfortunately, the actor Robin Williams was dealing with four of the major risk factors all together, which put him at a high risk of committing suicide and eventually led to his tragic death.

  10. Drosophila Model for the Analysis of Genesis of LIM-kinase 1-Dependent Williams-Beuren Syndrome Cognitive Phenotypes: INDELs, Transposable Elements of the Tc1/Mariner Superfamily and MicroRNAs

    Directory of Open Access Journals (Sweden)

    Elena V. Savvateeva-Popova

    2017-09-01

    Full Text Available Genomic disorders, the syndromes with multiple manifestations, may occur sporadically due to unequal recombination in chromosomal regions with specific architecture. Therefore, each patient may carry an individual structural variant of DNA sequence (SV with small insertions and deletions (INDELs sometimes less than 10 bp. The transposable elements of the Tc1/mariner superfamily are often associated with hotspots for homologous recombination involved in human genetic disorders, such as Williams Beuren Syndromes (WBS with LIM-kinase 1-dependent cognitive defects. The Drosophila melanogaster mutant agnts3 has unusual architecture of the agnostic locus harboring LIMK1: it is a hotspot of chromosome breaks, ectopic contacts, underreplication, and recombination. Here, we present the analysis of LIMK1-containing locus sequencing data in agnts3 and three D. melanogaster wild-type strains—Canton-S, Berlin, and Oregon-R. We found multiple strain-specific SVs, namely, single base changes and small INDEls. The specific feature of agnts3 is 28 bp A/T-rich insertion in intron 1 of LIMK1 and the insertion of mobile S-element from Tc1/mariner superfamily residing ~460 bp downstream LIMK1 3′UTR. Neither of SVs leads to amino acid substitutions in agnts3 LIMK1. However, they apparently affect the nucleosome distribution, non-canonical DNA structure formation and transcriptional factors binding. Interestingly, the overall expression of miRNAs including the biomarkers for human neurological diseases, is drastically reduced in agnts3 relative to the wild-type strains. Thus, LIMK1 DNA structure per se, as well as the pronounced changes in total miRNAs profile, probably lead to LIMK1 dysregulation and complex behavioral dysfunctions observed in agnts3 making this mutant a simple plausible Drosophila model for WBS.

  11. Investigating the ''social brain'' through Williams syndrome

    International Nuclear Information System (INIS)

    Nagamine, Masanori; Mimura, Masaru; Reiss, A.L.; Hoeft, F.

    2010-01-01

    Recent advances in social cognitive neuroscience have led to the concept of the ''social brain''. The social brain includes neural processes specialized for processing social information necessary for the recognition of self and others, and interpersonal relationships. Because of its unique behavioral phenotypic features which includes 'hypersociability', Williams syndrome has gained popularity among social cognitive neuroscientists. Individuals with Williams syndrome share the same genetic risk factor for cognitive-behavioral dysfunction utilizing brain imaging to elucidate endophenotype provides us with an unprecendented opportunity to study gene, brain and behavior relationships especially those related to social cognition. In this review, we provide an overview of neuroimaging studies on social cognition in Williams syndrome and discuss the neural basis of the social brain. (author)

  12. Dr. William C. Harris, Director-General, Science Foundation Ireland

    CERN Multimedia

    Maximilien Brice

    2002-01-01

    Photo 01: Dr William C. Harris, Director-General, Science Foundation Ireland (left) with R. Cashmore. Photos 02, 03: Dr William C. Harris, Director-General, Science Foundation Ireland signing the CERN guest book with R. Cashmore.

  13. William James, Gustav Fechner, and Early Psychophysics

    Science.gov (United States)

    Hawkins, Stephanie L.

    2011-01-01

    American psychologist and philosopher William James devoted the entirety of his career to exploring the nature of volition, as expressed by such phenomena as will, attention, and belief. As part of that endeavor, James’s unorthodox scientific pursuits, from his experiments with nitrous oxide and hallucinogenic drugs to his investigation of spiritualist mediums, represent his attempt to address the “hard problems” of consciousness for which his training in brain physiology and experimental psychology could not entirely account. As a student, James’s reading in chemistry and physics had sparked his interest in the concepts of energy and force, terms that he later deployed in his writing about consciousness and in his arguments against philosophical monism and scientific materialism, as he developed his “radically empiricist” ideas privileging discontinuity and plurality. Despite James’s long campaign against scientific materialism, he was, however, convinced of the existence of a naturalistic explanation for the more “wayward and fitful” aspects of mind, including transcendent experiences associated with hysteria, genius, and religious ecstasy. In this paper, I examine aspects of James’s thought that are still important for contemporary debates in psychology and neuroscience: his “transmission theory” of consciousness, his ideas on the “knowing of things together,” and, finally, the related concept of “the compounding of consciousness,” which postulates the theoretical possibility for individual entities within a conscious system of thought to “know” the thoughts of others within the system. Taken together, these ideas suggest that James, in spite of, or perhaps because of, his forays into metaphysics, was working toward a naturalistic understanding of consciousness, what I will term a “distributive model,” based on his understanding of consciousness as an “awareness” that interacts dynamically within, and in relation to

  14. William James, Gustav Fechner, and Early Psychophysics

    Directory of Open Access Journals (Sweden)

    Stephanie L. Hawkins

    2011-10-01

    Full Text Available American psychologist and philosopher William James devoted the entirety of his career to exploring the nature of volition, as expressed by such phenomena as will, attention, and belief. As part of that endeavor, James's unorthodox scientific pursuits, from his experiments with nitrous oxide and hallucinogenic drugs to his investigation of spiritualist mediums, represent his attempt to address the "hard problems" of consciousness for which his training in brain physiology and experimental psychology could not entirely account. As a student, James's reading in chemistry and physics had sparked his interest in the concepts of energy and force, terms that he later deployed in his writing about consciousness and in his arguments against philosophical monism and scientific materialism, as he developed his radically empiricist ideas privileging discontinuity and plurality. Despite James's long campaign against scientific materialism, he was, however, convinced of the existence of a naturalistic explanation for the more "wayward and fitful" aspects of mind, including transcendent experiences associated with hysteria, genius, and religious ecstasy. In this paper, I examine aspects of James's thought that are still important for contemporary debates in psychology and neuroscience: his "transmission theory" of consciousness, his ideas on the "knowing of things together," and, finally, the related concept of "the compounding of consciousness," which postulates the theoretical possibility for individual entities within a conscious system of thought to "know" the thoughts of others within the system. Taken together, these ideas suggest that James, in spite of, or perhaps because of, his forays into metaphysics, was working toward a naturalistic understanding of consciousness, what I will term a "distributive model," based on his understanding of consciousness as an "awareness" that interacts dynamically within, and in relation to, its environment.

  15. MRI Amygdala Volume in Williams Syndrome

    Science.gov (United States)

    Capitao, Liliana; Sampaio, Adriana; Sampaio, Cassandra; Vasconcelos, Cristiana; Fernandez, Montse; Garayzabal, Elena; Shenton, Martha E.; Goncalves, Oscar F.

    2011-01-01

    One of the most intriguing characteristics of Williams Syndrome individuals is their hypersociability. The amygdala has been consistently implicated in the etiology of this social profile, particularly given its role in emotional and social behavior. This study examined amygdala volume and symmetry in WS individuals and in age and sex matched…

  16. Williams-Beuren Syndrome with Brain Dysplasia

    Directory of Open Access Journals (Sweden)

    J Gordon Millichap

    2013-10-01

    Full Text Available Investigators from Jichi and Yokohama City Universities, Japan, report a patient with the common Williams-Beuren syndrome (WBS deletion in 7q11.23 who presented with severe cerebral and cerebellar dysplasia and progressive hypertrophic cardiomyopathy.

  17. The world in eighteen lessons: Christopher Williams

    NARCIS (Netherlands)

    Berrebi, S.

    2011-01-01

    Conceptual photographer Christopher Williams is a real artist's artist. Ever since he moved to Germany, his measured work, which both reveres and examines the art of photography, has more and more easily found its way into European art institutes, such as this spring at Museum Dhondt-Dhaenens in

  18. De wereld in 18 lessen: Christopher Williams

    NARCIS (Netherlands)

    Berrebi, S.

    2011-01-01

    Hij is een echte artist’s artist, de conceptuele fotograaf Christopher Williams. Sinds hij in Duitsland woont en werkt, vindt zijn afgewogen werk, dat de fotografie tegelijk eert en ondervraagt, steeds makkelijker onderdak in Europese kunstinstituten, zoals dit voorjaar bij Museum Dhondt-Dhaenens in

  19. Denigrating Carl Rogers: William Coulson's Last Crusade.

    Science.gov (United States)

    Kirschenbaum, Howard

    1991-01-01

    Reviews William Coulson's assertions that Carl Rogers, Abraham Maslow, and he initiated the humanistic education field, that Rogers repudiated his philosophy late in life, and that they owe the nation's parents an apology. Argues that these charges are groundless and provides examples and quotations from Rogers' later writings to show how Rogers…

  20. Fears, Hyperacusis and Musicality in Williams Syndrome

    Science.gov (United States)

    Blomberg, Stefan; Rosander, Michael; Andersson, Gerhard

    2006-01-01

    The study investigated the prevalence of fear and hyperacusis and the possible connections between fear, hyperacusis and musicality in a Swedish sample of individuals with Williams syndrome (WS). The study included 38 individuals and a cross-sectional design, with no matched control group. Two persons, who knew the participant well, completed a…

  1. William Lloyd Garrison and George Peabody.

    Science.gov (United States)

    Parker, Franklin

    1994-01-01

    This article presents an article by William Lloyd Garrison that criticize George Peabody, his wealth, his politics, and his motives for philanthropy. The article also presents a response by Franklin Parker which defends Peabody and explains the differences between his viewpoints, motives, and actions and those of Garrison. (SM)

  2. William Burroughs: Sailor of the Soul.

    Science.gov (United States)

    Lees, Andrew J

    2017-01-01

    In 1953, William Seward Burroughs made several important and largely unrecognized discoveries relating to the composition and clinical pharmacological effects of the hallucinogenic plant potion known as yagé or ayahuasca. Illustrations of Burroughs' voucher sample of Psychotria viridis and his letter to the father of modern ethnobotany, Richard Evans Schultes, are published here for the very first time.

  3. Epistemology in Excess? A Response to Williams

    Science.gov (United States)

    Siegei, Harvey

    2017-01-01

    Emma Williams' "In Excess of Epistemology" admirably endeavours to open the way to an account of critical thinking that goes beyond the one I have defended ad nauseum in recent decades by developing, via the work of Charles Taylor and Martin Heidegger, "a radically different conception of thinking and the human being who…

  4. William T. Grant Foundation 2012 Annual Report

    Science.gov (United States)

    William T. Grant Foundation, 2013

    2013-01-01

    The William T. Grant Foundation was founded in 1936 to support strong social science research focused on "the enrichment of life, with a primary interest in people and in their adjustment to the world in which they live." Today, its funding priorities reflect this interest in research that affects young people's lives. This Annual Report…

  5. William Hayes and His Pallanza Bomb Shell

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 16; Issue 10. William Hayes and His Pallanza Bomb Shell. R Jayaraman. General Article Volume 16 Issue 10 October 2011 pp 911-921. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/016/10/0911-0921 ...

  6. March 1964 Prince William Sound, USA Images

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Prince William Sound magnitude 9.2 Mw earthquake on March 28, 1964 at 03:36 GMT (March 27 at 5:36 pm local time), was the largest U.S. earthquake ever recorded...

  7. Sir William Withey Gull (1816-1890).

    Science.gov (United States)

    Pearce, J M S

    2006-01-01

    William Gull, a man of humble origins, became one of the outstanding, polymath physicians of the 19th century, and physician to Queen Victoria. Among several important and original contributions, this paper summarises his work on myxoedema, paraplegia and anorexia nervosa.

  8. Psycholinguistic Abilities of Children with Williams Syndrome

    Science.gov (United States)

    Rossi, Natalia F.; Heinze, Elena Garayzabal; Giacheti, Celia M.; Goncalves, Oscar F.; Sampaio, Adriana

    2012-01-01

    The objective of this study was to investigate the psycholinguistic abilities of children with Williams syndrome (WS) and typically developing children using the Illinois Test of Psycholinguistic Abilities (ITPA). Performance on the ITPA was analysed in a group with WS (N=20, mean age=8.5 years, SD=1.62) and two typically developing groups,…

  9. Seguridad social, empleo y propiedad privada en William Beveridge

    Directory of Open Access Journals (Sweden)

    Claudio Llanos Reyes

    2013-09-01

    Full Text Available This article aims to approach the economic and political notions of William Beveridge, which proposed the construction of the British Welfare State immediately after WWII. A form of State which sought to overcome the crisis of capitalism by proposing control over the system. We attempt to demonstrate the relation that should exist, according to Beveridge, the "father" of this model of capitalist State, between the development of a social security system, employment, and the situation of private property, while simultaneously pointing out the specifics and complexity of his ideas in the relation observed between full occupation and private property as basic elements for the construction of a Social Security system.

  10. Increased overall cortical connectivity with syndrome specific local decreases suggested by atypical sleep-EEG synchronization in Williams syndrome.

    Science.gov (United States)

    Gombos, Ferenc; Bódizs, Róbert; Kovács, Ilona

    2017-07-21

    Williams syndrome (7q11.23 microdeletion) is characterized by specific alterations in neurocognitive architecture and functioning, as well as disordered sleep. Here we analyze the region, sleep state and frequency-specific EEG synchronization of whole night sleep recordings of 21 Williams syndrome and 21 typically developing age- and gender-matched subjects by calculating weighted phase lag indexes. We found broadband increases in inter- and intrahemispheric neural connectivity for both NREM and REM sleep EEG of Williams syndrome subjects. These effects consisted of increased theta, high sigma, and beta/low gamma synchronization, whereas alpha synchronization was characterized by a peculiar Williams syndrome-specific decrease during NREM states (intra- and interhemispheric centro-temporal) and REM phases of sleep (occipital intra-area synchronization). We also found a decrease in short range, occipital connectivity of NREM sleep EEG theta activity. The striking increased overall synchronization of sleep EEG in Williams syndrome subjects is consistent with the recently reported increase in synaptic and dendritic density in stem-cell based Williams syndrome models, whereas decreased alpha and occipital connectivity might reflect and underpin the altered microarchitecture of primary visual cortex and disordered visuospatial functioning of Williams syndrome subjects.

  11. Rorty, Williams, and Davidson: Skepticism and Metaepistemology

    Directory of Open Access Journals (Sweden)

    Christopher Ranalli

    2013-07-01

    Full Text Available We revisit an important exchange on the problem of radical skepticism between Richard Rorty and Michael Williams. In his contribution to this exchange, Rorty defended the kind of transcendental approach to radical skepticism that is offered by Donald Davidson, in contrast to Williams’s Wittgenstein-inspired view. It is argued that the key to evaluating this debate is to understand the particular conception of the radical skeptical problem that is offered in influential work by Barry Stroud, a conception of the skeptical problem which generates metaepistemological ramifications for anti-skeptical theories. In particular, we argue that, contra Williams, Rorty’s view that Davidson was offering a theoretical diagnosis of radical skepticism can be consistently maintained with his transcendental approach.

  12. Forget Jerusalem: William Faulkner's Hyperreal Novel

    OpenAIRE

    Germana, Michael Joseph

    1999-01-01

    This paper explores the relationality between Modernism and Postmodernism as well as between literature and theory by examining the works of two writers: master novelist William Faulkner, and high priest of Postmodernism, Jean Baudrillard. Specifically, this paper examines Faulknerâ s eleventh novelâ the oft-neglected If I Forget Thee, Jerusalemâ as a proto-postmodern text which, when examined by the light of Baudrillardâ s theory of simulacra and simulations, informs the transition from...

  13. Sydafrikanske William S. Mazwis Lebenslauf (ca. 1928)

    DEFF Research Database (Denmark)

    Henningsen, Anne Folke

    2008-01-01

    Gennem teoretiske indsigter lånt fra psykologi, pædagogik, filosofi, lingvistik og litteraturvidenskab reflekteres over de metodologiske udfordringer, der kan møde forskeren i analyser af tekster produceret af den 'Anden'. I artiklen fokuseres på den herrnhutiske missionskirke i Sydafrika i begyn...... begyndelsen af det 20. århundrede, og den sorte herrnhuterpræst William S. Mazwis levnedsbeskrivelse analyseres som et eksempel på autoetnografisk selv-subjektivering. Udgivelsesdato: December...

  14. Neural Correlates of Amusia in Williams Syndrome

    OpenAIRE

    Lense, Miriam D.; Dankner, Nathan; Pryweller, Jennifer R.; Thornton-Wells, Tricia A.; Dykens, Elisabeth M.

    2014-01-01

    Congenital amusia is defined by marked deficits in pitch perception and production. Though historically examined only in otherwise typically developing (TD) populations, amusia has recently been documented in Williams syndrome (WS), a genetic, neurodevelopmental disorder with a unique auditory phenotype including auditory sensitivities and increased emotional responsiveness to music but variable musical skill. The current study used structural T1-weighted magnetic resonance imaging and diffus...

  15. Eutrophication analysis of embayments in Prince William Sound, Alaska

    International Nuclear Information System (INIS)

    Lung, Wu Seng; McCutcheon, S.C.

    1993-01-01

    Fertilizers were used in the summer of 1989 to accelerate bacterial growth in a bioremediation effort to clean up the beaches following the EXXON Valdez oil spill. Mathematical models were used to quantify the eutrophication potential in two selected embayments in Prince William Sound: Passage Cove and Snug Harbor. First, mass transport in these two embayments was determined. Next, eutrophication models were developed for these two embayments to simulate the seasonal algal concentrations prior to fertilizer application. Finally, a series of nutrient-loading scenarios based on different fertilizer and other chemical application rates were developed to investigate the impact. Model results and the data available indicated that the rapid exchange between embayments and the open water limits algal growth and buildup of concentrations of other chemicals applied to beaches. The exception is the potential for some ammonia toxicity at high application rates. Despite the limited data available it is clear that no significant increased algal growth would be expected following fertilizer application

  16. Quantifying Uncertainty in Estimations of the Total Weight of Drugs in Groups of Complex Matrices: Using the Welch-Satterthwaite Equation.

    Science.gov (United States)

    Alberink, Ivo; Sprong, Annette; Bolck, Annabel; Vergeer, Peter

    2017-07-01

    In this paper, a method is described to quantify estimations of the total amount of drugs in groups of seized items, including quantification of the precision. Previous work on this topic was based on the assumptions of normally distributed measurements and grouping of items with a common relative standard deviation. In practice, these assumptions are often violated, for example, for data with point masses at 0, or if certain items in a group have a very high standard deviation. The method described in this paper is based on work by Welch and Satterthwaite and does not assume constant relative standard deviations. Case examples are described for which the method is applied, and simulation studies are carried out for which both methods are applied. In the cases, both methods perform reasonably well. If the assumption of common relative standard deviations clearly does not apply, it is advised to use the method described. © 2016 American Academy of Forensic Sciences.

  17. John Dewey, William Wirt and the Gary Schools Plan: A Centennial Reappraisal

    Science.gov (United States)

    Thorburn, Malcolm

    2017-01-01

    A century on from the height of John Dewey's educational writings and the reputation of the Gary Schools Plan as a model of progressive education, the paper reappraises two key matters: the relationship between John Dewey and William Wirt, the first superintendent of the Gary Schools in Gary Indiana, and the coherence between John Dewey's…

  18. Validation of the Welch Allyn SureBP (inflation) and StepBP (deflation) algorithms by AAMI standard testing and BHS data analysis.

    Science.gov (United States)

    Alpert, Bruce S

    2011-04-01

    We evaluated two new Welch Allyn automated blood pressure (BP) algorithms. The first, SureBP, estimates BP during cuff inflation; the second, StepBP, does so during deflation. We followed the American National Standards Institute/Association for the Advancement of Medical Instrumentation SP10:2006 standard for testing and data analysis. The data were also analyzed using the British Hypertension Society analysis strategy. We tested children, adolescents, and adults. The requirements of the American National Standards Institute/Association for the Advancement of Medical Instrumentation SP10:2006 standard were fulfilled with respect to BP levels, arm sizes, and ages. Association for the Advancement of Medical Instrumentation SP10 Method 1 data analysis was used. The mean±standard deviation for the device readings compared with auscultation by paired, trained, blinded observers in the SureBP mode were -2.14±7.44 mmHg for systolic BP (SBP) and -0.55±5.98 mmHg for diastolic BP (DBP). In the StepBP mode, the differences were -3.61±6.30 mmHg for SBP and -2.03±5.30 mmHg for DBP. Both algorithms achieved an A grade for both SBP and DBP by British Hypertension Society analysis. The SureBP inflation-based algorithm will be available in many new-generation Welch Allyn monitors. Its use will reduce the time it takes to estimate BP in critical patient care circumstances. The device will not need to inflate to excessive suprasystolic BPs to obtain the SBP values. Deflation is rapid once SBP has been determined, thus reducing the total time of cuff inflation and reducing patient discomfort. If the SureBP fails to obtain a BP value, the StepBP algorithm is activated to estimate BP by traditional deflation methodology.

  19. Obituary: William K. Rose (1935-2010)

    Science.gov (United States)

    Trimble, Virginia

    2011-12-01

    Stellar astrophysicist William Kenneth Rose died near his home in Potomac, Maryland, on September 30, 2010, after an extended illness. Rose was the son of pharmacist Kenneth William Rose and Shirley Near Rose and was born in Ossining, New York, on August 10, 1935. He received an AB from Columbia College in 1957 and a PhD in physics from Columbia University in 1963, with a thesis on "measurements of linear polarization in discrete radio sources using a 9.4 cm maser," under the direction of Charles H. Townes. Rose played a major role in designing and constructing the maser and used it at a radio telescope at Maryland Point that belonged to the Naval Research Lab. He observed Jupiter and Saturn and a number of extra-solar-system sources, and also diffuse centimeter emission (see appendix). The thesis was not published in an archival journal, but can be found under Library of Congress code QB 475.R67. While in graduate School, Bill married Sheila Tuchman, whose primary scientific interests were biological. None of their three children chose to be scientists, but two are CPAs. Bill moved successfully through the academic hurdles) from a research position at Princeton (1963-67), where a collaboration with Nick Woolf and Martin Schwarzchild on the infrared spectra of giant stars became one of his most-cited papers, to assistant and associate professorships at MIT (1967-71), and then associate and full professorships at the University of Maryland (1971 to retirement in 2005). His most innovative work was probably that on nova explosions arising from degenerate ignition of hydrogen accreted on white dwarfs in close binary systems, published in 1968. The same idea occurred to others at about the same time, and Bill did not, perhaps, get quite his fair share of the credit. I first met Sheila and Bill in summer 1969 at the Stony Brook summer school on stellar evolution (not published until 1972). He lectured on the nature of nova explosions and on nuclear burning in thin

  20. WILLIAM HAZLITT, OBSESSIVE LOVE, AND LIBER AMORIS.

    Science.gov (United States)

    Trosman, Harry

    2017-07-01

    William Hazlitt, a distinguished literary figure of the early nineteenth century and a forerunner of psychoanalytic insights, had a keen awareness of the impact of the imagination on assessing works of art. At forty-two, he became hopelessly involved in an obsessive love affair with a nineteen-year-old woman and could not extricate himself from the relationship. The affair followed the death of his father, a powerful influence on his life. Factors in his obsessive love included finding an object of idealization subject to his imaginative creation and narcissistically reexperiencing himself about to begin a new life. © 2017 The Psychoanalytic Quarterly, Inc.

  1. TENNESSEE WILLIAMS E O TEATRO MARGINAL GAY

    Directory of Open Access Journals (Sweden)

    Adriana Falqueto Lemos

    2014-09-01

    Full Text Available The work developed in this text aims to read the dramatist Tennnessee Williams in a play in two scenes “E Contar Tristes Histórias das Mortes das Bonecas” which was published in Brazil in the book “Mister Paradise e outras peças em um ato” (2011. The intention is to reflect upon one of his recurring themes, the marginalization. In order to perform the analysis, the theoretical support was grounded in “Literatura e Sociedade” by Antonio Candido (2006, concerning the participation of society and authorship in a piece of literature.

  2. Enough room for Williams and IMF? / Paul Beckman

    Index Scriptorium Estoniae

    Beckman, Paul

    1999-01-01

    Lõppesid Leedu ja USA energeetikakompanii Williams International läbirääkimised Leedu naftakompleksis osaluse omandamise asjus. IMF uurib Leedu majanduslikku arengut, mida tehing Williamsiga komplitseerib

  3. The scientific legacy of William Herschel

    CERN Document Server

    2018-01-01

    This book presents a modern scholarly analysis of issues associated with England’s most famous astronomer, William Herschel. The world’s leading experts on Herschel, discoverer of the planet Uranus, here offer their combined wisdom on many aspects of his life and astronomical research. Solar system topics include comets, Earth’s Moon, and the spurious moons of Uranus, all objects whose observation was pioneered by Herschel.  The contributors examine his study of the structure of the Milky Way and an in-depth look at the development of the front view telescopes he built. The popular subject of extraterrestrial life is looked at from the point of view of both William Herschel and his son John, both of whom had an interest in the topic. William’s personal development through the educational system of the late eighteenth-century is also explored, and the wide range of verse and satire in various languages associated with his discoveries is collected here for the first time. Hershel worked at a time of i...

  4. William Burchell's medical challenges: A 19th-century natural ...

    African Journals Online (AJOL)

    William Burchell's medical challenges: A 19th-century natural philosopher in the field. R Stewart. Abstract. Two hundred years ago, the naturalist William John Burchell departed from Cape Town on extensive travels in South Africa 'solely for the purpose of acquiring knowledge'. An intelligent observer who was exceptionally ...

  5. The William and Flora Hewlett Foundation | IDRC - International ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    The William and Flora Hewlett Foundation. The William and Flora Hewlett Foundation. http://www.hewlett.org/. Think Tank Initiative. This initiative is creating high-quality independent research and policy institutions throughout the developing world. View more. Think Tank Initiative. Growth and Economic Opportunities for ...

  6. Response to the letter, Williams syndrome: was intubation rather ...

    African Journals Online (AJOL)

    Du Toit-Prinsloo L, Dippenaar JM, Honey EM. Case report of sudden death in a child with Williams syndrome following administration of anaesthesia. S Afr J Anaesth Analg. 2015;21(1):75–8. 2. Cook T. Williams syndrome: was intubation rather than anaesthetic drug choice a cause of cardiac arrest? S Afr J Anaesth Analg.

  7. "The Country and the City" by Raymond Williams. Essay Review.

    Science.gov (United States)

    Johnson, Jerry D.; Howley, Craig B.

    2000-01-01

    Reviews essays by Raymond Williams, which explain how, within the context of a 150-year literary history, rural stereotypes have been constructed and imbedded within a collective consciousness by a form of cultural colonization. Suggests that Williams' insights can help rural education researchers think outside the conventional wisdom that…

  8. 76 FR 2902 - Williams, Barry Lawson; Notice of Filing

    Science.gov (United States)

    2011-01-18

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. ID-2449-005] Williams, Barry Lawson; Notice of Filing January 10, 2011. Take notice that on January 10, 2011, Barry Lawson Williams submitted for filing, an application for authority to hold interlocking positions, pursuant to section 305(b...

  9. 75 FR 62530 - Williams, Barry Lawson; Notice of Filing

    Science.gov (United States)

    2010-10-12

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. ID-6409-000] Williams, Barry Lawson; Notice of Filing October 4, 2010. Take notice that on September 24, 2010, Barry Lawson Williams submitted for filing, an application for authority to hold interlocking positions, pursuant to [[Page 62531...

  10. Discovering Structure in Auditory Input: Evidence from Williams Syndrome

    Science.gov (United States)

    Elsabbagh, Mayada; Cohen, Henri; Karmiloff-Smith, Annette

    2010-01-01

    We examined auditory perception in Williams syndrome by investigating strategies used in organizing sound patterns into coherent units. In Experiment 1, we investigated the streaming of sound sequences into perceptual units, on the basis of pitch cues, in a group of children and adults with Williams syndrome compared to typical controls. We showed…

  11. Sir William Henry Perkin: The Man and his 'Mauve'

    Indian Academy of Sciences (India)

    Senior Perkin used to get copies of building plans made by. William with the intention, in addition to using his drawing skill, to influence William to take up .... with it for the dye soared making the business of Perkin & Sons. 1. 1 In the Classics Section (p.856), the details of the patent applica- tion including the procedure for.

  12. Malformations vasculaires au cours du syndrome de Williams ...

    African Journals Online (AJOL)

    Le syndrome de Williams-Beuren est une maladie génétique rare, il associe classiquement une dysmorphie faciale assez spécifique, des malformations cardiovasculaires et un profil neuropsychologique particulier. Nous rapportons les observations de trois enfants atteints du syndrome de Williams-Beuren en insistant ...

  13. William Bateson: a biologist ahead of his time

    Indian Academy of Sciences (India)

    Unknown

    Journal of Genetics, Vol. 81, No. 2, August 2002. 49. PERSPECTIVES. William Bateson: a ... Family life was filled with conversation and William and his siblings grew up to be strong-willed, disputatious and .... alkaptonurics having children together was known. Garrod had both male and female alkaptonuric patients and he.

  14. Mental Health Problems in Adults with Williams Syndrome

    Science.gov (United States)

    Stinton, Chris; Elison, Sarah; Howlin, Patricia

    2010-01-01

    Although many researchers have investigated emotional and behavioral difficulties in individuals with Williams syndrome, few have used standardized diagnostic assessments. We examined mental health problems in 92 adults with Williams syndrome using the Psychiatric Assessment Schedule for Adults with Developmental Disabilities--PAS-ADD (Moss,…

  15. Pursuing the Panderer: An Analysis of "United States v. Williams"

    Science.gov (United States)

    McGrain, Patrick N.; Moore, Jennifer L.

    2010-01-01

    In May 2008, the Supreme Court addressed whether the government can regulate the ownership and distribution of virtual child pornography. "U.S. v. Williams" marked the first time the Court directly addressed the concept of pandering virtual child pornography. This article examines the Court's decision in "U.S. v. Williams" and…

  16. William Osler's "The Nervousness of American Women".

    Science.gov (United States)

    Golden, Richard L

    2008-02-01

    Almost a century ago, William Osler, the foremost physician of his time, was approached by a leading periodical to write a series of articles on the health of the American woman. Osler, then the Regius Professor of Medicine at Oxford, wrote an essay dealing with the psychological stresses affecting the "new woman" of the early 20th century at varying stages of her development and the "nervousness" that ensued. The article was never published as a result of his belated reservations on the propriety of a professional writing for a lay journal. Osler's thinking frequently reflected the spirit of his Victorian-Edwardian era, although at times he demonstrated advanced and prescient ideas about sexuality, not often the subject of discussion, even in circumspect form, in contemporary nonprofessional literature.

  17. Robert Williams Wood: pioneer of invisible light.

    Science.gov (United States)

    Sharma, Shruti; Sharma, Amit

    2016-03-01

    The Wood's lamp aids in the diagnosis of multiple infectious, inflammatory and neoplastic dermatologic conditions. Although the Wood's lamp has many applications, which have improved both the diagnosis and management of disease, the man credited for its invention is relatively unknown in medicine. Robert Williams Wood, a prominent physicist of the early 20th century, is credited for the invention of the Wood's lamp. Wood was the father of infrared and ultraviolet photography and made significant contributions to other areas in optics and spectroscopy. Wood's work encompassed the formative years of American Physics; he published over 200 original papers over his lifetime. A few years after the invention of the Wood's lamp for ultraviolet photography, physicians in Europe adopted the Wood's lamp for dermatologic applications. Wood's lamp remains popular in clinics globally, given its ease of use and ability to improve diagnostic precision. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  18. Random Thoughts on William Shakespeare and Medicine

    Directory of Open Access Journals (Sweden)

    KV Sahasranam

    2017-04-01

    Full Text Available Medicine and literature have always been connected over the ages. William Shakespeare (1564-1616 is no exception. There are plenty of references to medicine and diseases in the works of Shakespeare. The knowledge which Shakespeare has of medical conditions is much more than is expected of a common man. This is attributed to his association with practitioners of his time and reading of contemporary texts in medicine. Also his son in law Dr. John Hall who married Susanna, Shakespeare's eldest daughter would have contributed substantially to the knowledge of medicine in Shakespeare's compositions. Surgery at the Elizabethan times was well known and is reflected to a large extent in his plays.

  19. William Cavendish: the man behind the lab

    Science.gov (United States)

    Constable, Anthony

    2008-02-01

    It is not at all unusual for a wealthy aristocrat to provide substantial funds for building an academic institution. But it is highly unusual that the aristocrat concerned should have been steeped in the education, science and industry for which the institution would become justly famous. The man who provided all the necessary funds to build and equip the Cavendish Laboratory at Cambridge University in the UK was William Cavendish, who succeeded his father's cousin as 7th Duke of Devonshire in 1858 and became chancellor of the university in 1861. He had crowned his own undergraduate career at Cambridge in 1829 at Trinity College with the awards of second Wrangler and first Smiths Prize, and in the same year, aged just 21, was elected a fellow of the Royal Society.

  20. Syntax and morphology in Williams syndrome.

    Science.gov (United States)

    Clahsen, H; Almazan, M

    1998-09-01

    Williams syndrome (WS) is a neuro-developmental disorder which is characterized by an unusual fractionation of language abilities and other cognitive functions. We have investigated four cases of English-speaking subjects with WS, and we show that despite their low IQs the WS children's performance on syntactic tasks and on regular inflection is not impaired. Irregular inflection, however, is affected causing many errors. We also report results from studies investigating the same linguistic phenomena in children with specific language impairment. These children exhibit a different pattern of impairment, with relatively poor performance on syntactic tasks and regular inflection. We suggest a linguistic characterization of the morphosyntax in WS according to which WS subjects are impaired in accessing (particular kinds of) information from lexical entries, with their computational system for language appearing to be intact. We interpret the selective impairments found in WS and SLI as supporting the theoretical distinction between a computational system and an associative memory system for language.

  1. A Mystic in English Literature: William Blake

    Directory of Open Access Journals (Sweden)

    Ali Fahri DOĞAN

    2015-12-01

    Full Text Available Human beings have never been satisfied with this ephemeral world. Perhaps, yearning and desire of rejoining −stemming from the descent from the heaven to the earth− are the emotions felt by the members of both celestial and non-celestial religions. Mysticism, having started with the zeal of people who weren‘t satisfied with this ephemeral world towards the eternal world, aimed at the love of God in the religions where there is a belief of single God. In this article, glancing at the life of a Christian mystic William Blake, we will try to shed light into his mystic thoughts. While studying Blake‘s mystic thoughts, there will be common points with Sufism. Nevertheless, analysis of these common points has been assigned to other studies.

  2. [William W. Cadbury and canton hospital].

    Science.gov (United States)

    Liu, Ze-Sheng; Liu, Ze-En

    2004-01-01

    William W. Cadbury M.D. was born in Philadelphia, USA and graduated from the Medical College of Pennsylvania University. It was nearly 40 years since he arrived in Canton (Guangzhou) in 1909 and left at retirement age. He taught western medicine in Canton Christian College and worked as a medical doctor in Canton Hospital, the oldest western medical hospital in the Orient. He was regarded as a famous foreign doctor and an excellent professor in internal medicine in the Republic of China. He wrote At the point of Lancet: 100 years of Canton Hospital 1835 - 1935, which recorded the achievement made by American missionary doctors, particularly the pioneers such as Peter Parker M.D. and John G. Kerr. M.D. So far the book is still an important reference for the studies on history of western medicine in China and the history of modern medical exchange between China and other countries.

  3. 77 FR 72413 - William Blair & Company, L.L.C. and William Blair Funds.; Notice of Application

    Science.gov (United States)

    2012-12-05

    ... invest in China A shares. Applicants: William Blair and William Blair Funds (the ``Trust''). Filing Dates... existing series of the Trust, the Emerging Markets Growth Fund (the ``Initial Fund)'' \\1\\ currently desires... China A-Share Fund, which will rely on the exemptions from registration under the Act provided by...

  4. Characterisation of sheet cavity noise of a hydrofoil using the Ffowcs Williams-Hawkings acoustic analogy

    OpenAIRE

    Lidtke, Artur Konrad; Turnock, Stephen; Humphrey, Victor

    2016-01-01

    Concerns about pollution of the marine environment with ship-induced noise and the scarcity of available numerical methods have recently stimulated significant amounts of research in hydroacoustic modelling. In this work, Large Eddy Simulation (LES) is used with Schnerr-Sauer mass-transfer cavitation model and a porous Ffowcs Williams-Hawkings (FW-H) acoustic analogy in order to simulate sheet cavitation on a NACA0009 hydrofoil. The aim is to investigate how well the proposed method captures ...

  5. Bayesian stock assessment of Pacific herring in Prince William Sound, Alaska.

    Directory of Open Access Journals (Sweden)

    Melissa L Muradian

    Full Text Available The Pacific herring (Clupea pallasii population in Prince William Sound, Alaska crashed in 1993 and has yet to recover, affecting food web dynamics in the Sound and impacting Alaskan communities. To help researchers design and implement the most effective monitoring, management, and recovery programs, a Bayesian assessment of Prince William Sound herring was developed by reformulating the current model used by the Alaska Department of Fish and Game. The Bayesian model estimated pre-fishery spawning biomass of herring age-3 and older in 2013 to be a median of 19,410 mt (95% credibility interval 12,150-31,740 mt, with a 54% probability that biomass in 2013 was below the management limit used to regulate fisheries in Prince William Sound. The main advantages of the Bayesian model are that it can more objectively weight different datasets and provide estimates of uncertainty for model parameters and outputs, unlike the weighted sum-of-squares used in the original model. In addition, the revised model could be used to manage herring stocks with a decision rule that considers both stock status and the uncertainty in stock status.

  6. Modeling a scientific career: an essential component of the mentorship process. An interview with John A. Williams, Professor of Molecular and Integrative Physiology, University Of Michigan, Ann Arbor, Mich., USA by Martín E. Fernández-Zapico.

    Science.gov (United States)

    Williams, John A

    2010-01-01

    In the current interview article, Dr. John A. Williams shares his experiences, and provides career advice to junior investigators. Dr. Williams is one of the world's leading physiologists working on signal transduction mechanisms in pancreatic acinar cells. He is worldwide recognized for his contribution to many areas of pancreatology, especially the understanding of GI hormone regulation of pancreatic exocrine function. and IAP.

  7. Discoverers of the universe William and Caroline Herschel

    CERN Document Server

    Hoskin, Michael

    2011-01-01

    Discoverers of the Universe tells the gripping story of William Herschel, the brilliant, fiercely ambitious, emotionally complex musician and composer who became court astronomer to Britain's King George III, and of William's sister, Caroline, who assisted him in his observations of the night sky and became an accomplished astronomer in her own right. Together, they transformed our view of the universe from the unchanging, mechanical creation of Newton's clockmaker god to the ever-evolving, incredibly dynamic cosmos that it truly is. William was in his forties when his amateur observations usi

  8. William Blake: escritura y lectura iluminadas

    Directory of Open Access Journals (Sweden)

    Daniela Picón

    2011-04-01

    Full Text Available Considerando que la fuerza divina es un poder propiamente humano, que permite trascender desde la mera visualización y percepción sensorial del mundo finito y terrenal hacia el reino eterno y verdadero de la imaginación, el poeta, artista y visionario inglés William Blake (1757-1827 identificó a dios con dicha facultad humana. En su lucha contra la ‘religión de la razón’, bajo cuyo poder el hombre se había limitado a la ‘vacía’ percepción exterior, Blake buscará recobrar la ‘religión de la imaginación’. Desde esta perspectiva, este estudio pretende dilucidar el modo en que la materialidad de lo escrito (Roger Chartier y la utilización de un método de escritura particular por parte del visionario -distinto al que su propio tiempo le ofrecía- afecta el circuito de la comunicación visionaria de comienzo a fin, relacionándose directamente con la finalidad que Blake otorgó a sus poemas proféticos iluminados: despertar en los lectores esa capacidad visionaria y verdadera que ‘reside en el pecho de todos los hombres’.Considering the ‘divine force’ as a human power that allows humans to transcend from the mere sensory visualization and perception of the finite and earthly world to the true and eternal realm of imagination, William Blake, the english poet, artist and visionary (1757-1827 identified god with this human faculty. In his struggle against the ‘religion of reason’, under which humans had been reduced to an ‘empty’ outward perception, Blake wants to recover the ‘religion of imagination’. From this perspective, I expect to elucidate the ways in which the material aspects of writing (Roger Chartier and the visionary use of a specific method of writing -different from the methods available to Blake in his own time- affect the visionary circuit of communication. This complete transformation is directly connected with the purpose of Blake’s illuminated prophetic poems: he intends to awake in his

  9. National uranium resource evaluation: Williams quadrangle, Arizona

    International Nuclear Information System (INIS)

    O'Neill, A.J.; Nystrom, R.J.; Thiede, D.S.

    1981-03-01

    Geologic environments of the Williams Quadrangle, Arizona, were evaluated for uranium favorability by means of literature research, uranium-occurrence investigation and other surface studies, subsurface studies, aerial radiometric data, hydrogeochemical data, and rock-sample analytic data. Favorability criteria are those of the National Uranium Resource Evaluation program. Three geologic environments are favorable for uranium: the Tertiary fluvial rocks of the Colorado Plateau where they unconformably overlie impermeable bed rock (for channel-controlled peneconcordant deposits); collapse breccia pipes in Paleozoic strata of the Colorado Plateau (for vein-type deposits in sedimentary rocks); and Precambrian crystalline rocks of the Hualapai, Peacock, and Aquarius Mountains, and Cottonwood and Grand Wash Cliffs (for magmatic-hydrothermal deposits). Unfavorable geologic environments are: Tertiary and Quaternary volcanic rocks, Tertiary and Quaternary sedimentary rocks of the Colorado Plateau, nearly all Paleozoic and Mesozoic sedimentary rocks, and the Precambrian-Cambrian unconformity of the Grand Wash Cliffs area. Tertiary rocks in Cenozoic basins and Precambrian crystalline rocks in the Grand Canyon region and in parts of the Aquarius Mountains and Cottonwood and Grand Wash Cliffs are unevaluated

  10. Sir William Mitchell (1925-2002)

    CERN Document Server

    2002-01-01

    Sir William (Bill) Mitchell, former President of the CERN Council, died on 30th October 2002 at the age of 77. Mitchell was professor of Physics at Oxford University from 1978 to 1989, having previously been Professor of Physics, Dean of Science and Deputy Vice-Chancellor at Reading University. From 1985 to 1990 he was Chairman of the UK's Science and Engineering Research Council (SERC), which at the time was the funding agency for the UK's participation in the CERN programme. As Chairman, Mitchell was one of the UK representatives on the CERN Council, and in 1991 he was elected President, a position he held for three years. This was a difficult period for CERN. Financial problems were being faced in many member states, notably in Germany as a result of unification. This led to calls for reductions in the CERN budget and, more significantly, to requests for delays in consderation of future programmes. On the other hand for the future of CERN and the progress of elementary particle physics, it was necessary...

  11. William L. Donn 1918-1987

    Science.gov (United States)

    Gedzelman, Stanley David

    William L. Donn, Professor Emeritus of the Department of Earth and Planetary Sciences, City College of New York, and Special Research Scientist at Lamont-Doherty Geological Observatory (LDGO) of Columbia University (Palisades, N.Y.), died at his home on June 30, 1987, at the age of 69. Bill demonstrated expertise in a wide range of fields, with a highly productive and creative research and writing career that included geology, oceanography, climatology, atmospheric physics, and meteorology.Donn was born in Brooklyn, N.Y., on March 2, 1918. At the tender age of 10 years, he demonstrated his love and talent for science by building a telescope with his brother, Bertram. During his undergraduate years at Brooklyn College, he switched his major from astronomy to geology. He was largely selftrained in both meteorology and oceanography, serving as head of the Meteorology Section, U.S. Merchant Marine Academy during World War II . One by-product of these years was the textbook Meteorology—With Marine Applications, first published in 1946. This widely adopted text became a standard for a generation of mariners and college students.

  12. Neural correlates of amusia in williams syndrome.

    Science.gov (United States)

    Lense, Miriam D; Dankner, Nathan; Pryweller, Jennifer R; Thornton-Wells, Tricia A; Dykens, Elisabeth M

    2014-11-21

    Congenital amusia is defined by marked deficits in pitch perception and production. Though historically examined only in otherwise typically developing (TD) populations, amusia has recently been documented in Williams syndrome (WS), a genetic, neurodevelopmental disorder with a unique auditory phenotype including auditory sensitivities and increased emotional responsiveness to music but variable musical skill. The current study used structural T1-weighted magnetic resonance imaging and diffusion tensor imaging to examine neural correlates of amusia in 17 individuals with WS (4 of whom met criteria for amusia). Consistent with findings from TD amusics, amusia in WS was associated with decreased fractional anisotropy (FA) in the right superior longitudinal fasciculus (SLF). The relationship between amusia and FA in the inferior component of the SLF was particularly robust, withstanding corrections for cognitive functioning, auditory sensitivities, or musical training. Though the number of individuals with amusia in the study is small, results add to evidence for the role of fronto-temporal disconnectivity in congenital amusia and suggest that novel populations with developmental differences can provide a window into understanding gene-brain-behavior relationships that underlie musical behaviors.

  13. Neural Correlates of Amusia in Williams Syndrome

    Directory of Open Access Journals (Sweden)

    Miriam D. Lense

    2014-11-01

    Full Text Available Congenital amusia is defined by marked deficits in pitch perception and production. Though historically examined only in otherwise typically developing (TD populations, amusia has recently been documented in Williams syndrome (WS, a genetic, neurodevelopmental disorder with a unique auditory phenotype including auditory sensitivities and increased emotional responsiveness to music but variable musical skill. The current study used structural T1-weighted magnetic resonance imaging and diffusion tensor imaging to examine neural correlates of amusia in 17 individuals with WS (4 of whom met criteria for amusia. Consistent with findings from TD amusics, amusia in WS was associated with decreased fractional anisotropy (FA in the right superior longitudinal fasciculus (SLF. The relationship between amusia and FA in the inferior component of the SLF was particularly robust, withstanding corrections for cognitive functioning, auditory sensitivities, or musical training. Though the number of individuals with amusia in the study is small, results add to evidence for the role of fronto-temporal disconnectivity in congenital amusia and suggest that novel populations with developmental differences can provide a window into understanding gene-brain-behavior relationships that underlie musical behaviors.

  14. Prince William Sound, Alaska ESI: FISH (Fish Polygons)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set comprises the Environmental Sensitivity Index (ESI) data for Prince William Sound, Alaska. ESI data characterize estuarine environments and wildlife by...

  15. Prince William Sound, Alaska ESI: SOCECON (Socioeconomic Points)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set comprises the Environmental Sensitivity Index (ESI) data for Prince William Sound, Alaska. ESI data characterize estuarine environments and wildlife by...

  16. Prince William Sound, Alaska ESI: FISH (Fish Lines)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set comprises the Environmental Sensitivity Index (ESI) data for Prince William Sound, Alaska. ESI data characterize estuarine environments and wildlife by...

  17. Prince William Sound, Alaska ESI: NESTS (Bird Nests)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set comprises the Environmental Sensitivity Index (ESI) data for Prince William Sound, Alaska. ESI data characterize estuarine environments and wildlife by...

  18. Accuracy of the Welch Allyn SureSight for measurement of magnitude of astigmatism in 3- to 7-year-old children.

    Science.gov (United States)

    Harvey, Erin M; Dobson, Velma; Miller, Joseph M; Clifford-Donaldson, Candice E; Green, Tina K; Messer, Dawn H; Garvey, Katherine A

    2009-10-01

    To evaluate the accuracy of the Welch Allyn SureSight in noncycloplegic measurements of astigmatism as compared to cycloplegic Retinomax K+ autorefractor measurements of astigmatism in children from a Native American population with a high prevalence of high astigmatism. Data are reported for 825 3- to 7-year-old children with no ocular abnormalities. Each child had a Retinomax K+ cycloplegic measurement of right eye astigmatism with a confidence rating > or =8 and 3 attempts to obtain a SureSight measurement on the right eye. SureSight measurement success rates did not differ significantly across age or measurement confidence rating ( or =6). Ninety-six percent of children had at least 1 measurement (any confidence), and 89% had at least 1 measurement with confidence at the manufacturer's recommended value (> or =6). Overall, the SureSight tended to overestimate astigmatism. If the SureSight measurement had any dioptric value (0.00 D to 3.00 D), astigmatism of 2.00 D or less was likely to be present. If the SureSight showed astigmatism beyond the instrument's dioptric range (>3.00 D), Retinomax K+ measurements indicated that >2.00 D of astigmatism was present in 136 of 157 (86.6%). In cooperative children for whom the SureSight would not give a reading, 32 of 34 (94%) had >3.00 D of astigmatism. The SureSight does not provide an accurate, quantitative measure of amount of astigmatism. However, it does allow accurate categorization of amount of astigmatism as 2.00 D, or >3.00 D, and it has high measurement success rate in young children.

  19. Harold Stannet Williams and Nagasaki--from the viewpoint of philosophical anthropology

    OpenAIRE

    木村, 博

    2010-01-01

    From the viewpoint of philosophical anthropology, this paper will consider the true character of Harold Stannet Williams. In his book, The Story of HOLME RINGER and CO., LTD. IN WESTERN JAPAN 1868-1968, H.S. Williams indicates that he felt a great interest in Nagasaki. Williams rates Frederick Ringer's work highly. As a historian, Williams attached importance to a search for historical facts. At the same time, however, Williams emphasized the importance of 'soul’ in his writings. This paper w...

  20. Welches Geschlecht hat die Avantgarde?

    Directory of Open Access Journals (Sweden)

    Gertrud Lehnert

    2000-07-01

    Full Text Available Das Buch betrachtet das Theater der französischen und amerikanischen ‚Avantgarde‘ der Moderne und Postmoderne unter dem Aspekt des Geschlechts: Welcher Verfahren bedient sich avantgardistische Kunst, ist avantgardistische Kunst in geschlechtlicher Hinsicht restriktiv, oder ermöglicht sie die subversive feministische oder auch lesbisch-schwule Ausformung spezifischer Formen?

  1. William Byrd: Political and Recusant Composer

    Directory of Open Access Journals (Sweden)

    Ariel Foshay Bacon

    2012-05-01

    Full Text Available Amidst the pendulum of political and religious upheaval that pervaded England throughout the sixteenth and seventeenth century, William Byrd stands as one of the best loved and lauded composers. Byrd succeeded in the secular and sacred realms, contributing great works to the Anglican Church, popularizing the English madrigal and producing prolific amounts of sacred music. However, in a time where one’s religious beliefs were often linked with political loyalty, Byrd defied his monarch’s established and enforced Protestant religion, composing politically charged music for recusant use in clandestine Catholic Church services. His themes were aligned with the Jesuit mission and his texts were often drawn from the lips of martyred Catholics at the gallows; their last words forever immortalized by Byrd for the furthering of the Jesuit cause and the Counter-Reformation. The examination of sources by prominent Byrd scholars, an analyses of Byrd’s ‘political’ compositions and a study of the social and historical background are used to place Byrd within the appropriate context, prove his recusant and political leanings, and analyze his precarious relationship with the English monarch, Elizabeth I. It is shown that Byrd could not have proceeded with his recusant practices, personally or musically, had it not been for his status as a composer, as well as Byrd’s shrewdness in procuring diplomatic relationships with high persons at court and with Queen Elizabeth I through the Chapel Royal. Finally, Byrd’s success at writing for the Anglican Church service and popular secular music showcased his ability to take a moderate stance in situations that benefitted his status with the crown

  2. Increase in suicides the months after the death of Robin Williams in the US.

    Science.gov (United States)

    Fink, David S; Santaella-Tenorio, Julian; Keyes, Katherine M

    2018-01-01

    Investigating suicides following the death of Robin Williams, a beloved actor and comedian, on August 11th, 2014, we used time-series analysis to estimate the expected number of suicides during the months following Williams' death. Monthly suicide count data in the US (1999-2015) were from the Centers for Disease Control and Prevention Wide-ranging ONline Data for Epidemiologic Research (CDC WONDER). Expected suicides were calculated using a seasonal autoregressive integrated moving averages model to account for both the seasonal patterns and autoregression. Time-series models indicated that we would expect 16,849 suicides from August to December 2014; however, we observed 18,690 suicides in that period, suggesting an excess of 1,841 cases (9.85% increase). Although excess suicides were observed across gender and age groups, males and persons aged 30-44 had the greatest increase in excess suicide events. This study documents associations between Robin Williams' death and suicide deaths in the population thereafter.

  3. Obituary: William A. Rense (1914-2008)

    Science.gov (United States)

    Cushman, Glen

    2009-12-01

    On March 28, 2008, the space research community lost another of its pioneers. William A. Rense, professor emeritus of physics at the University of Colorado in Boulder, who died in Estes Park, Colorado, following complications from cancer. He was 94. Bill, as he was widely known, was born in 1914 in Massillon, Ohio, the son of German immigrants. His was a large family - five brothers and one sister. His father, Joseph Rense, worked for the city of Cleveland while his mother, Rosalia (Luther) Rense was a housewife. As a child, Bill developed a love of astronomy which led him to earn a bachelor's degree in physics and astronomy from Case Western Reserve University in Cleveland, followed by master's and PhD degrees in physics at Ohio State University. He held teaching positions at Rutgers, University of Miami (Florida), Texas A & M, and Louisiana State University before taking his final appointment at CU in 1949. While teaching at LSU, he met and in 1942 married Wanda (Childs) Rense. In addition to teaching physics at CU, Bill did research in CU's Upper Air Laboratory. His early work there included studies of polarized light and its implications for the analysis of zodiacal light. He and his co-workers also began developing instrumentation to be flown above the Earth's atmosphere in sounding rockets. In 1952 he obtained the first photographic spectrogram of the solar Lyman-alpha line of hydrogen (121.6nm). This work was followed in 1956 by the first full disk spectroheliogram in Lyman-alpha. These results could not have been possible without the use of pointing control systems for sounding rockets. These "sun trackers" kept the payloads pointed at the sun long enough for the measurements to be made, and CU was a pioneer in their development. The expanding research venue led the Upper Air Laboratory to be renamed the Laboratory for Atmospheric and Space Physics (LASP), and Bill Rense was its first director. He continued his research into the properties of the solar

  4. [William Osler (1849-1919): the man and his descriptions].

    Science.gov (United States)

    Young, Pablo; Finn, Bárbara C; Bruetman, Julio E; Emery, John D C; Buzzi, Alfredo

    2012-09-01

    William Osler was generally regarded as the greatest and most respected physician of his time. This paper describes Osler's life, his philosophy and views. He was an outstanding clinician who emphasized bedside teaching and observation. He possessed an extraordinary charm that inspired many others. As Professor of Medicine at four institutions in three countries, he was a great influence on medical education. He was a prolific writer, and his textbook became the most popular and widely read treatise on medicine in the world. He also was a medical historian, a classical scholar, and an avid bibliophile. He emphasized the value of hard work and ongoing education. His compassion and concern for patients and colleagues reflected his personality. We summarize Osler's descriptions, and some of his aphorisms. His wisdom is as relevant now, as it was in his time. Osler blended the art and science of Medicine perhaps better than anyone else, and remains a valuable role model for students and physicians more than ninety two years after his death.

  5. Narrative competence in Spanish-speaking adults with Williams syndrome.

    Science.gov (United States)

    Diez-Itza, Eliseo; Martínez, Verónica; Antón, Aránzazu

    2016-08-01

    Williams syndrome (WS) is a genetic disorder associated with intellectual disability and characterised by displaying an atypical neuropsychological profile, with peaks and valleys, where language skills seem better preserved than non-verbal intelligence. This study researches the narrative competence of nine Spanish-speaking adults with WS. Oral narratives were elicited from a silent film, and narrative coherence was analysed as a function of sequential order of the events narrated at three structure levels, while narrative cohesion was assessed through the frequency of use and type of discourse markers. WS subjects were able to remember a significant proportion of the events from the film, but coherence of narratives, i.e., sequential order of events, was more impaired. Consistently with their linguistic abilities, cohesion of narratives was better preserved, as they used discourse markers to introduce a high proportion of events. Construction of mental models of the narratives may be constrained in WS by non-verbal cognitive abilities, but narrative competence is also determined by textual pragmatic abilities to organize discourse, which should be addressed by specific intervention in narrative competence.

  6. Recent paleoseismicity record in Prince William Sound, Alaska, USA

    Science.gov (United States)

    Kuehl, Steven A.; Miller, Eric J.; Marshall, Nicole R.; Dellapenna, Timothy M.

    2017-12-01

    Sedimentological and geochemical investigation of sediment cores collected in the deep (>400 m) central basin of Prince William Sound, along with geochemical fingerprinting of sediment source areas, are used to identify earthquake-generated sediment gravity flows. Prince William Sound receives sediment from two distinct sources: from offshore (primarily Copper River) through Hinchinbrook Inlet, and from sources within the Sound (primarily Columbia Glacier). These sources are found to have diagnostic elemental ratios indicative of provenance; Copper River Basin sediments were significantly higher in Sr/Pb and Cu/Pb, whereas Prince William Sound sediments were significantly higher in K/Ca and Rb/Sr. Within the past century, sediment gravity flows deposited within the deep central channel of Prince William Sound have robust geochemical (provenance) signatures that can be correlated with known moderate to large earthquakes in the region. Given the thick Holocene sequence in the Sound ( 200 m) and correspondingly high sedimentation rates (>1 cm year-1), this relationship suggests that sediments within the central basin of Prince William Sound may contain an extraordinary high-resolution record of paleoseismicity in the region.

  7. Pursuing the panderer: an analysis of United States v. Williams.

    Science.gov (United States)

    McGrain, Patrick N; Moore, Jennifer L

    2010-03-01

    In May 2008, the Supreme Court addressed whether the government can regulate the ownership and distribution of virtual child pornography. U.S. v. Williams marked the first time the Court directly addressed the concept of pandering virtual child pornography. This article examines the Court's decision in U.S. v. Williams and the relative importance of its holding. In U.S. v. Williams, the Supreme Court upheld an act of Congress targeting the business people behind the child pornography market. Restricting the sale of both real and virtual child pornography is essential to combat the various problems surrounding its existence, which include policing its creation and distribution on the Internet as well as the connection between child pornography and subsequent sexual offenses against children.

  8. Antonio Gramsci en los estudios culturales de Raymond Williams

    Directory of Open Access Journals (Sweden)

    Álvaro Alonso Trigueros

    2014-05-01

    Full Text Available Este artículo intenta poner de manifiesto la deuda de los estudios culturales de Raymond Williams con la obra del filólogo-político Antonio Gramsci. En concreto, intenta demostrar cómo Williams encuentra en Gramsci el método adecuado para analizar las manifestaciones artístico-culturales en relación con la lucha por la hegemonía y cómo es a partir de Gramsci que pueden ser entendidos los desarrollos posteriores de los estudios culturales, desde Williams hasta Stuart Hall. Mediante el análisis de la obra de Williams y a partir del conocimiento del pensamiento de Gramsci hemos sido capaces de encontrar la herencia de Gramsci como elemento decisivo en la fundación de los estudios culturales tal y como nacen de manera multidisciplinar a partir de los pioneros trabajos en este campo de Raymond Williams. Asimismo podemos llegar a la conclusión de que tanto los Quaderni de Gramsci como los denominados “escritos juveniles” supusieron para Williams el descubrimiento no sólo del método adecuado para analizar las manifestaciones artístico-culturales en relación con la hegemonía, sino que además Gramsci aportó un número importante de problemáticas y palabras clave sobre las que han sido fundados posteriormente los estudios culturales en las distintas universidades de manera global.

  9. Obituary: William L. Kraushaar, 1920-2008

    Science.gov (United States)

    Clark, George W.

    2009-01-01

    Professor William L. Kraushaar, a former MIT physics professor and a pioneer in the field of high-energy astronomy, died 21 March 2008 of complications from Parkinson's disease. He was 87. Kraushaar received his bachelor's degree from Lafayette College in 1942. During World War II he worked at the National Bureau of Standards on projects that included development of the proximity fuse for artillery shells. After the war he earned his doctorate at Cornell University. In 1949 Kraushaar was appointed research associate at MIT, where he made the first measurements of the mean life of the pi meson at the MIT electron synchrotron. Over the next fifteen years he rose through the faculty ranks, becoming a full professor before leaving MIT for the University of Wisconsin at Madison in 1965. In 1957 Kraushaar began a decade-long effort to map the sky in the "light" of cosmic gamma rays. Their detection promised to open new ways to investigate high-energy processes in the universe. Initial balloon-borne experiments failed due to background gamma rays generated in the residual atmosphere above the highest attainable altitudes. In 1958, Kraushaar seized a new opportunity for experiments above the atmosphere. Working with Professor George Clark, he directed the development in the MIT Laboratory for Nuclear Science of a gamma-ray detector for a satellite experiment that was launched in April 1961 as Explorer 11. It registered 31 events with the electronic signatures of cosmic gamma rays with energies greater than 50 MeV. Kraushaar then initiated a second and more refined experiment to be carried on OSO 3. In this project Kraushaar and Clark were joined by Gordon Garmire, a former student of Kraushaar. The OSO 3 experiment, launched in March of 1967, registered 621 cosmic gamma-ray events. It yielded the first all-sky map of high-energy cosmic gamma rays showing a concentration of gamma rays from directions in the Milky Way where gamma-ray producing interactions of charged cosmic

  10. Williams syndrome in a child with a multiple organ pathology

    Directory of Open Access Journals (Sweden)

    T. V. Mihajlova

    2017-01-01

    Full Text Available The article describes the clinical case of Williams syndrome with the combined pathology of many systems and organs: mental retardation, congenital heart disease (supravalvular aortic stenosis, arterial hypertension, hypercalcemia, hypercalciuria complicated by nephrocalcinosis, gastrointestinal tract injury, facial and eye anomalies, hernia of anterior abdominal wall, kyphoscoliosis. Microsatellite analysis of the loci of the critical region of chromosome 7 revealed a deletion of the investigated loci (D7S1870, D7S613, D7S2476, D7SEln, which led to the diagnosis of Williams syndrome.

  11. Sir William Osler's speech at Troy: a Trojan horse?

    OpenAIRE

    Moran, Michael E.

    2012-01-01

    Troy, New York, is a city of 55,000 people in upstate New York located along the Hudson River. A city of surprisingly rich cultural heritage, it was the home of New York state's first hospital outside New York City. The 50th anniversary celebration of Troy's hospital brought William Osler to the city as the keynote speaker. This speech, delivered on November 28, 1900, is one of Sir William's less well known addresses. Osler began his comments with Sir Thomas More's Utopia and talked at length...

  12. John Whitridge Williams' contribution to democracy abroad. (The fetus treated as a patient).

    Science.gov (United States)

    Vasicka, A

    1999-04-01

    The idealism of American pioneers was a driving force in the development of science, democracy, and sociology in the United States. It also served as a model for the development of new democracies abroad. The first American grafted democracy was established in Czechoslovakia in 1918, under Thomas Garrigue Masaryk as President. As a former professor of philosophy, at Charles University in Prague, he built the foundation of Czechoslovakian democracy on the historical principles of Jan Hus' search for the truth (1415), Jan Amos Komensky's use of Science and Humanism (1630), and on the values of American democracy as he conceived it from multiple visits to the United States and from the practical philosophy of his American wife. His major educational means was the use of science. He became a founder of political science. As president he recognized, that democracy, as a state form, does not educate people, they educate themselves through family, school, church, physician and life experience. In the last quarter of the nineteenth century, on the eve of the opening of John Hopkin's University Hospital, a young American scientist by the name John Whitridge Williams came to Prague, Vienna, and other Europeans cities for the purpose of studying scientific obstetrics. He believed in the power of the truth in the power of the truth equally as Masaryk did and used science uncompromisingly in his speciality. He became the founder of American scientific obstetrics. He was shy of political science and ethnic problems. There was no personal connection between Masaryk and Williams. In 1903, John Whitridge Williams published his review of European and American obstetrics: he abolished the craft of obstetrics and worked the science of physiology and pathology into the practice of obstetrics. For Czechoslovaks the political democracy coming out of America through Masaryk was attractive, but of particular interest was native and personal democracy of Americans as a way of life. John

  13. A Surge of Interest in Uganda's Art Deco | Craddock Williams ...

    African Journals Online (AJOL)

    A Surge of Interest in Uganda's Art Deco. Vivian Craddock Williams. Abstract. No Abstract. Full Text: EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT · http://dx.doi.org/10.4314/uj.v46i1.23038 · AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians ...

  14. La Fondation William et Flora Hewlett | IDRC - International ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    La Fondation William et Flora Hewlett. http://www.hewlett.org/ · What we do · Funding · Resources · About IDRC. Knowledge. Innovation. Solutions. Careers · Contact Us · Site map. Sign up now for IDRC news and views sent directly to your inbox each month. Subscribe · Copyright · Open access policy · Privacy policy ...

  15. Gender Attribution and Gender Agreement in French Williams Syndrome

    Science.gov (United States)

    Boloh, Yves; Ibernon, Laure; Royer, Stephanie; Escudier, Frederique; Danillon, Aurelia

    2009-01-01

    Previous studies on grammatical gender in French individuals with Williams syndrome (WS) have led to conflicting findings and interpretations regarding keys abilities--gender attribution and gender agreement. New production data from a larger SW sample (N = 24) showed that gender attribution scores in SW participants exactly mirrored those of…

  16. Examining Reports of Mental Health in Adults with Williams Syndrome

    Science.gov (United States)

    Stinton, Chris; Tomlinson, Katie; Estes, Zachary

    2012-01-01

    Prior research suggests that individuals with Williams syndrome (WS) have a disposition towards anxiety. Information regarding this is typically derived from parents and carers. The perspectives of the individuals with WS are rarely included in research of this nature. We examined the mental health of 19 adults with WS using explicit (psychiatric…

  17. Shepard Award Winners, Part 2: Dr. Tracie Williams

    Centers for Disease Control (CDC) Podcasts

    2009-07-29

    This podcast highlights the accomplishments of Dr. Tracie Williams, recipient of the prestigious 2009 CDC Charles C. Shepard Award.  Created: 7/29/2009 by Centers for Disease Control and Prevention (CDC).   Date Released: 7/29/2009.

  18. William Morris and John Dewey: Imagining Utopian Education

    Science.gov (United States)

    Freeman-Moir, John

    2012-01-01

    With strikingly resonance William Morris and John Dewey independently imagined what utopian education might plausibly be. Neither remotely thought of utopia as a perfectly ordered society, but rather as a process. Each understood education functionally in terms of how it fits with art, work, and democracy within a holistic conception of utopia.…

  19. Edward Christopher Williams and His Impact on Librarianship.

    Science.gov (United States)

    Latimer, Carlos

    Edward Christopher Williams had a major impact on librarianship, not only as the first documented African American to graduate from a library school, but also as a developer of education for librarians and as an active member of the American Library Association (ALA) and the Ohio Library Association. This study used the historical methodology…

  20. Musicality Correlates with Sociability and Emotionality in Williams Syndrome

    Science.gov (United States)

    Ng, Rowena; Lai, Philip; Levitin, Daniel J.; Bellugi, Ursula

    2013-01-01

    Williams syndrome (WS) is a neurogenetic developmental disorder characterized by peaks and valleys of cognitive abilities. One peak that has been understudied is the affinity that many individuals with WS have with music. It remains unknown whether their high levels of musical interest, skill, and expressivity are related to their sociable…

  1. Adaptive Functioning in Williams Syndrome: A Systematic Review

    Science.gov (United States)

    Brawn, Gabrielle; Porter, Melanie

    2018-01-01

    Literature on the level of adaptive functioning and relative strengths and weaknesses in functioning of individuals with Williams syndrome (WS) was reviewed. The electronic databases PsycINFO, PubMed, Expanded Academic, Web of Science, Scopus and ProQuest were searched electronically for relevant articles and dissertations using the search terms…

  2. Comparison of the acute effects of Tulbaghia violacea William Henry ...

    African Journals Online (AJOL)

    Purpose: To assess the effect of the crude methanol leaf extracts of Tulbaghia violacea William Henry Harvey (Alliaceae) on blood pressure (BP) and heart rate in ageing normotensive Wistar Kyoto rats (WKY), and compare the results obtained with those for adult spontaneously hypertensive rats (SHR). Methods: T.

  3. The Poetics of "Pattern Recognition": William Gibson's Shifting Technological Subject

    Science.gov (United States)

    Wetmore, Alex

    2007-01-01

    William Gibson's 1984 cyberpunk novel "Neuromancer" continues to be a touchstone in cultural representations of the impact of new information and communication technologies on the self. As critics have noted, the posthumanist, capital-driven, urban landscape of "Neuromancer" resembles a Foucaultian vision of a panoptically engineered social space…

  4. Public Educators as Interpretive Critics: Edward Said and Raymond Williams

    Science.gov (United States)

    Nixon, Jon

    2008-01-01

    The work of Edward Said and Raymond Williams exemplifies an important aspect of the role of the public intellectual as educator. This paper concentrates on the significance of their work as public educators and on the tradition of interpretive criticism as they developed it within the field of literary and cultural theory. The argument builds from…

  5. Biblionef SA: Bringing books to the bookless | Williams | Innovation

    African Journals Online (AJOL)

    Biblionef SA: Bringing books to the bookless. Jean Williams. Abstract. No abstract available. Innovation (2003) No. 26, pp 43-47. Full Text: EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT · AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians ...

  6. Experiences of Bullying for Individuals with Williams Syndrome

    Science.gov (United States)

    Fisher, Marisa H.; Lough, Emma; Griffin, Megan M.; Lane, Laurel A.

    2017-01-01

    Background: Individuals with intellectual disability experience high rates of bullying, but it is not known how people with specific syndromes, such as Williams syndrome (WS), experience and respond to bullying. Given their behavioral profile, including hypersociability and heightened anxiety, and their risk for experiencing other forms of…

  7. Florence Jessie MacWilliams (1917-1990)

    Indian Academy of Sciences (India)

    famous mathematician Oscar Zariski, well known for his work in algebraic geometry, at. Johns Hopkins University, following him to Harvard University to study with him for a year. There was a break in her studies for many years following her marriage in 1941 to. W al ter Mac Williams, an engineer, and the birth and raising of ...

  8. Language and Literacy Development of Children with Williams Syndrome

    Science.gov (United States)

    Mervis, Carolyn B.

    2009-01-01

    Williams syndrome is a rare neurodevelopmental disorder caused by deletion of approximately 25 genes on chromosome 7q11.23. Children with the syndrome evidence large individual differences in both broad language and reading abilities. Nevertheless, as a group, children with this syndrome show a consistent pattern characterized by relative…

  9. Love and Work: A Reading of John Williams' "Stoner"

    Science.gov (United States)

    Frank, Jeff

    2017-01-01

    This article offers a close reading of the novel Stoner by John Williams. "Stoner," and not the countless reports and jeremiads on teaching, helps us find what we are searching for: a way to live--and talk about--teaching in a dignified and artful way. We need to seek out voices that remind, recall and reveal teaching for the beautifully…

  10. Discourse Analysis of Tennessee Williams' "The Glass Menagerie"

    Science.gov (United States)

    Nalliveettil, George Mathew; Gadallah, Mahmoud Sobhi Mohamed

    2016-01-01

    "The Glass Menagerie" is one of the Tennessee Williams' most famous plays which won the New York Drama Critics' Circle award. It elevated him to be one of the greatest playwrights of his generation. As a playwright, he is skilful to make the readers conscious of the unconscious habits and attitudes in everyday life. In "The Glass…

  11. An Effective Leader in Higher Education: Charles William Eliot

    Science.gov (United States)

    Elliott, Robert Wayne; Paton, Valerie Osland

    2014-01-01

    While responding to increasing calls for accountability, educational leaders are challenged continually by a myriad of complex tasks amidst the need to adapt their postsecondary institutions for responding to the changing needs of society. This review of literature examines comparisons between the leadership style of Charles William Eliot and the…

  12. Williams Syndrome: Daily Challenges and Positive Impact on the Family

    Science.gov (United States)

    Scallan, Susan; Senior, Joyce; Reilly, Colin

    2011-01-01

    Background: Despite the distinctive physical, cognitive, personality and behavioural characteristics associated with Williams syndrome, few studies to date have examined parental experiences of raising a child with this genetic syndrome. Methods: This explorative pilot study employed predominantly qualitative methodologies via face-to-face…

  13. Williams-Beuren syndrome associated with single kidney and ...

    African Journals Online (AJOL)

    Williams-Beuren syndrome is a rare neurodevelopmental disorder, characterized by congenital heart defects, abnormal facial features, mental retardation with specific cognitive and behavioral profile, growth hormone deficiency, renal and skeletal anomalies, inguinal hernia, infantile hypercalcaemia. We report a case with ...

  14. Comprehension of Metaphor and Metonymy in Children with Williams Syndrome

    Science.gov (United States)

    Annaz, Dagmara; Van Herwegen, Jo; Thomas, Michael; Fishman, Roza; Karmiloff-Smith, Annette; Rundblad, Gabriella

    2009-01-01

    Background: Figurative language, such as metaphor and metonymy, is very common in daily language use. Its underlying cognitive processes are sometimes viewed as lying at the interface of language and thought. Williams syndrome, which is a rare genetic developmental disorder, provides an opportunity to study this interface because individuals with…

  15. William J. Jenkins Receives 2010 Maurice Ewing Medal

    Science.gov (United States)

    Doney, Scott C.; Kurz, Mark; Jenkins, William J.

    2011-02-01

    William J. Jenkins was awarded the 2010 Maurice Ewing Medal at the AGU Fall Meeting Honors Ceremony, held on 15 December 2010 in San Francisco, Calif. The medal is for “significant original contributions to the scientific understanding of the processes in the ocean; for the advancement of oceanographic engineering, technology, and instrumentation; and for outstanding service to the marine sciences.”

  16. Best Practices Case Study: Tommy Williams Homes -Gainesville, FL

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2011-04-01

    Case study of Tommy Williams Homes who has continued to outsell the competition with sales increasing despite the recession thanks to a systems-engineering approach developed with DOE’s Building America that yields high energy efficiency, comfort, and indoor air quality. The company offers to pay buyers’ energy bills for the first year.

  17. Potential Beneficial Effects of Tulbaghia violacea William Henry ...

    African Journals Online (AJOL)

    Tulbaghia violacea William Henry Harvey (Harv. Alliaceae) is a small bulbous herb belonging to the family Alliaceae. It is used in South Africa to treat fever, colds, asthma, paralysis, and hypertension. Meanwhile, cardiovascular disease accounts for about 30 % of total global death, with most of these deaths occurring in low ...

  18. Personal Space Regulation in Williams Syndrome: The Effect of Familiarity

    Science.gov (United States)

    Lough, Emma; Flynn, Emma; Riby, Deborah M.

    2016-01-01

    Personal space refers to a protective barrier that we strive to maintain around our body. We examined personal space regulation in young people with Williams syndrome (WS) and their typically developing, chronological age-matched peers using a parent report questionnaire and a stop-distance paradigm. Individuals with WS were reported by their…

  19. Beyond Behaviour: Is Social Anxiety Low in Williams Syndrome?

    Science.gov (United States)

    Dodd, Helen F.; Schniering, Carolyn A.; Porter, Melanie A.

    2009-01-01

    Individuals with Williams syndrome (WS) exhibit striking social behaviour that may be indicative of abnormally low social anxiety. The present research aimed to determine whether social anxiety is unusually low in WS and to replicate previous findings of increased generalised anxiety in WS using both parent and self report. Fifteen individuals…

  20. William Faulkner: No Friend of Brown v. Board of Education.

    Science.gov (United States)

    Polsgrove, Carol

    2001-01-01

    In the years following the Supreme Court's Brown v. Board of Education decision to integrate America's public schools, William Faulkner, Norman Mailer, Hannah Arendt, Robert Penn Warren, and, to a lesser extent, C. Vann Woodward, provided intellectual sustenance to southern efforts to resist racial integration. Focuses on Faulkner's political…

  1. The Interplay between Anxiety and Social Functioning in Williams Syndrome

    Science.gov (United States)

    Riby, Deborah M.; Hanley, Mary; Kirk, Hannah; Clark, Fiona; Little, Katie; Fleck, Ruth; Janes, Emily; Kelso, Linzi; O'Kane, Fionnuala; Cole-Fletcher, Rachel; Allday, Marianne Hvistendahl; Hocking, Darren; Cornish, Kim; Rodgers, Jacqui

    2014-01-01

    The developmental disorder Williams syndrome (WS) has been associated with an atypical social profile of hyper-sociability and heightened social sensitivity across the developmental spectrum. In addition, previous research suggests that both children and adults with WS have a predisposition towards anxiety. The current research aimed to explore…

  2. I Know! It's Backwards Day! Gender Roles and William's Doll

    Science.gov (United States)

    Van de Kleut, Geraldine

    2007-01-01

    This article presents a case study of an exploration of gender roles in a second-grade classroom. The author discusses some of the discursive identities in which she and her students are positioned, and then uses the picture book William's Doll to introduce a discussion of discursive gender identities with her students. She then asks students to…

  3. The attempts of William Dean and Wentzel van Huyssteen

    African Journals Online (AJOL)

    Abstract. This paper aims at creating a third option to foundatio- nalism and relativism. It criticizes William Dean's his- toricist radical empiricism for going too far toward a relativist deconstructionism, and Wentzel van Huys- steen's critical realism for not leaving modernism. Both, however, succeed in creating a third option.

  4. Language and Williams Syndrome: How Intact is "Intact"?

    Science.gov (United States)

    Karmiloff-Smith, Annette; And Others

    1997-01-01

    Examined morphosyntax in persons with Williams Syndrome (WS). Analyzed receptive language of English-speaking WS persons and grammatical gender assignment of French-speaking WS persons. Found within-domain dissociations in grammatical gender assignment across several sentence elements and difficulties in understanding embedded sentences, which…

  5. Characterisation of Sleep Problems in Children with Williams Syndrome

    Science.gov (United States)

    Annaz, Dagmara; Hill, Catherine M.; Ashworth, Anna; Holley, Simone; Karmiloff-Smith, Annette

    2011-01-01

    Sleep is critical to optimal daytime functioning, learning and general health. In children with established developmental disorders sleep difficulties may compound existing learning difficulties. The purpose of the present study was to evaluate the prevalence and syndrome specificity of sleep problems in Williams syndrome (WS), a…

  6. William Knocke receives 2008 Virginia Outstanding Civil Engineer Award

    OpenAIRE

    Daniilidi, Christina

    2008-01-01

    William R. Knocke, W.C. English Professor and head of the Charles E. Via, Jr. Department of Civil and Environmental Engineering at Virginia Tech, was awarded the 2008 Virginia Outstanding Civil Engineer Award at the Virginia Section of the American Society of Civil Engineers' (ASCE) banquet, held recently in Williamsburg, Va.

  7. Drosophila Model for the Analysis of Genesis of LIM-kinase 1-Dependent Williams-Beuren Syndrome Cognitive Phenotypes: INDELs, Transposable Elements of the Tc1/Mariner Superfamily and MicroRNAs

    Czech Academy of Sciences Publication Activity Database

    Savvateeva-Popova, E.V.; Zhuravlev, A.V.; Brázda, Václav; Zakharov, G.A.; Kaminskaya, A.N.; Medvedeva, A.V.; Nikitina, E.; Tokmatcheva, E.V.; Dolgaya, J.F.; Kulikova, D.A.; Zatsepina, O.; Funikov, S.Y.; Ryazansky, S.S.; Evgen'ev, Michail B.

    2017-01-01

    Roč. 8, SEP2017 (2017), č. článku 123. ISSN 1664-8021 Institutional support: RVO:68081707 Keywords : b dna conformations * swiss-model * copy number * polytene chromosomes Subject RIV: EB - Genetics ; Molecular Biology OBOR OECD: Biochemistry and molecular biology Impact factor: 3.789, year: 2016

  8. 76 FR 1187 - Application for Recertification of Prince William Sound Regional Citizens' Advisory Council

    Science.gov (United States)

    2011-01-07

    ... Prince William Sound Regional Citizens' Advisory Council AGENCY: Coast Guard, DHS. ACTION: Notice of... advisory group in lieu of a Regional Citizens' Advisory Council for Prince William Sound, Alaska. This... on, the application for recertification submitted by the Prince William Sound Regional Citizen's...

  9. 78 FR 27190 - Williams-Sonoma, Inc., Provisional Acceptance of a Settlement Agreement and Order

    Science.gov (United States)

    2013-05-09

    ... CONSUMER PRODUCT SAFETY COMMISSION [CPSC Docket No. 13-C0005] Williams-Sonoma, Inc., Provisional...(e). Published below is a provisionally-accepted Settlement Agreement with Williams- Sonoma, Inc.... 2051-2089 (CPSA) and 16 CFR 1118.20, Williams-Sonoma, Inc. (WS), and the United States Consumer Product...

  10. 75 FR 22436 - Michael Williams-Control Exemption-St. Maries River Railroad, Inc.

    Science.gov (United States)

    2010-04-28

    ... DEPARTMENT OF TRANSPORTATION Surface Transportation Board [Docket No. FD 35365] Michael Williams-Control Exemption-St. Maries River Railroad, Inc. Michael Williams (applicant),\\1\\ a noncarrier, has filed..., LLC, by Williams Group, Inc. (WG).\\2\\ Applicant currently controls two Class III railroads through...

  11. 77 FR 2241 - Radio Broadcasting Services; Ehrenberg, First Mesa, Kachina Village, Wickenburg, and Williams, AZ...

    Science.gov (United States)

    2012-01-17

    ...-2058] Radio Broadcasting Services; Ehrenberg, First Mesa, Kachina Village, Wickenburg, and Williams, AZ...., proposes the allotment of FM Channel 287C2 at Williams, Arizona, as the community's second local service... Williams allotment, we issue an Order to Show Cause to Univision Radio License Corporation as to why its...

  12. 33 CFR 161.60 - Vessel Traffic Service Prince William Sound.

    Science.gov (United States)

    2010-07-01

    ... William Sound. 161.60 Section 161.60 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND... Movement Reporting System Areas and Reporting Points § 161.60 Vessel Traffic Service Prince William Sound... Cape Hinchinbrook Light to Schooner Rock Light, comprising that portion of Prince William Sound between...

  13. Bathymetry of Lake William C. Bowen and Municipal Reservoir #1, Spartanburg County, South Carolina, 2008

    Science.gov (United States)

    Nagle, D.D.; Campbell, B.G.; Lowery, M.A.

    2009-01-01

    The increasing use and importance of lakes for water supply to communities enhance the need for an accurate methodology to determine lake bathymetry and storage capacity. A global positioning receiver and a fathometer were used to collect position data and water depth in February 2008 at Lake William C. Bowen and Municipal Reservoir #1, Spartanburg County, South Carolina. All collected data were imported into a geographic information system database. A bathymetric surface model, contour map, and stage-area and -volume relations were created from the geographic information database.

  14. Antonio Gramsci en los estudios culturales de Raymond Williams

    Directory of Open Access Journals (Sweden)

    Álvaro Alonso Trigueros

    2014-05-01

    Full Text Available Este artículo intenta poner de manifiesto la deuda de los estudios culturales de Raymond Williams con la obra del filólogo-político Antonio Gramsci. En concreto, intenta demostrar cómo Williams encuentra en Gramsci el método adecuado para analizar las manifestaciones artístico-culturales en relación con la lucha por la hegemonía y cómo es a partir de Gramsci que pueden ser entendidos los desarrollos posteriores de los estudios culturales, desde Williams hasta Stuart Hall. Mediante el análisis de la obra de Williams y a partir del conocimiento del pensamiento de Gramsci hemos sido capaces de encontrar la herencia de Gramsci como elemento decisivo en la fundación de los estudios culturales tal y como nacen de manera multidisciplinar a partir de los pioneros trabajos en este campo de Raymond Williams. Asimismo podemos llegar a la conclusión de que tanto los Quaderni de Gramsci como los denominados “escritos juveniles” supusieron para Williams el descubrimiento no sólo del método adecuado para analizar las manifestaciones artístico-culturales en relación con la hegemonía, sino que además Gramsci aportó un número importante de problemáticas y palabras clave sobre las que han sido fundados posteriormente los estudios culturales en las distintas universidades de manera global. Normal 0 21 false false false ES X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabla normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso

  15. Gluon propagator in non-Abelian Weizsaecker-Williams fields

    International Nuclear Information System (INIS)

    Ayala, A.; Jalilian-Marian, J.; McLerran, L.; Venugopalan, R.

    1995-01-01

    We carefully compute the gluon propagator in the background of a non-Abelian Weizsaecker-Williams field. This background field is generated by the valence quarks in very large nuclei. We find contact terms in the small fluctuation equations of motion which induce corrections to a previously incorrect result for the gluon propagator in such a background field. The well-known problem of the Hermiticity of certain operators in the light cone gauge is resolved for the Weizsaecker-Williams background field. This is achieved by working in a gauge where singular terms in the equations of motion are absent and then gauge transforming the small fluctuation fields to the light cone gauge

  16. William Foote Whyte, Street Corner Society and social organization.

    Science.gov (United States)

    Andersson, Oscar

    2014-01-01

    Social scientists have mostly taken it for granted that William Foote Whyte's sociological classic Street Corner Society (SCS, 1943) belongs to the Chicago school of sociology's research tradition or that it is a relatively independent study which cannot be placed in any specific research tradition. Social science research has usually overlooked the fact that William Foote Whyte was educated in social anthropology at Harvard University, and was mainly influenced by Conrad M. Arensberg and W. Lloyd Warner. What I want to show, based on archival research, is that SCS cannot easily be said either to belong to the Chicago school's urban sociology or to be an independent study in departmental and idea-historical terms. Instead, the work should be seen as part of A. R. Radcliffe-Brown's and W. Lloyd Warner's comparative research projects in social anthropology. © 2013 Wiley Periodicals, Inc.

  17. Ischemic Stroke in Williams-Beuren Syndrome: A Case Report

    Directory of Open Access Journals (Sweden)

    Wei-Der Lee

    2009-04-01

    Full Text Available A 15-year-old girl was admitted because of an acute onset of facial palsy and right hemiparesis. The patient had a history of moderate mental retardation and developmental delay. On admission, her vital signs were stable, except for high blood pressure. Magnetic resonance imaging demonstrated an infarct involving the left internal capsule and putamen. Because of the patient's young age, an extensive stroke survey was performed. Williams-Beuren syndrome was finally confirmed by fluorescent in situ hybridization. Compared with the previously reported cases, no evidence of cerebral arterial stenosis or cardiac abnormalities was found by noninvasive imaging techniques. Because Williams-Beuren syndrome is a complex, multiple congenital anomaly syndrome with prominent cardiovascular features, regular assessment and antihypertensive treatment are necessary to minimize the lifelong cardiovascular risk in patients with this syndrome.

  18. La Fondation William et Flora Hewlett | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    La Fondation William et Flora Hewlett. http://www.hewlett.org/. Initiative Think tank. Cette initiative permet d'établir des organismes indépendants qui se consacrent à la recherche et à l'élaboration de politiques dans des pays en développement. Voir davantage. Initiative Think tank. Croissance de l'économie et débouchés ...

  19. OBITUARY: Sir William Mitchell Physicist and enthusiast for science

    CERN Multimedia

    Cowley, R

    2002-01-01

    "William Mitchell was successively head of Physics at Reading and Oxford universities, and Chairman of the Science and Engineering Research Council from 1985 to 1990. He is largely responsible for the excellent neutron and X-ray facilities that are available for research by scientists in the UK. He was one of the first to realise that these uniquely powerful facilities would be essential tools not only for physicists but also for chemists, biologists, materials scientists and engineers" (1 page).

  20. William H. Sheldon and the culture of the somatotype

    OpenAIRE

    Gatlin, Stephen H.

    1997-01-01

    The burden of this dissertation is to show that William Sheldon's somatotype project should be seen as an integral aspect of modernist culture. Sheldon engaged the same problems with modernity and the "Second Industrial Revolution" (urbanization, overpopulation, industrialization, alienation) that confronted modernist poets, novelists, and philosophers. In this I am elaborating Dorothy Ross's recent metaphor, "modernist impulses in the human sciences" (1994). Both scientists and artists were ...

  1. Environmental mutagenesis and radiation biology: The legacy of William Morgan.

    Science.gov (United States)

    Schwartz, Jeffrey L

    2017-12-01

    A symposium entitled Environmental Mutagenesis and Radiation Biology was held on September 27, 2016 to honor the memory of Dr. William F. Morgan who passed away unexpectedly on November 13, 2015. The speakers presented the latest reviews on homologous recombination repair, induced genetic instability, bystander effects, and risk estimate development. Their presentations are presented following the introduction. Copyright © 2017 Elsevier B.V. All rights reserved.

  2. Robert W. Williams: Forgotten Pioneer of Spinal Мicrosurgery.

    Science.gov (United States)

    Stone, James L; Arnold, Paul M; Chowdhry, Shakeel A; Charbel, Fady

    2016-08-15

    In the 1970's many neurosurgeons gradually adapted microsurgical techniques to spine surgery as the benefits of magnification, illumination, and use of fine instruments in cranial surgery became apparent. In the early 1970 s, Robert W. Williams, а neurosurgeon in private practice in Las Vegas, Nevada, independently began to devise spinal microneurosurgical techniques with the goal of improving surgical outcome in lumbar and cervical surgery. Much of his initial work with microlumbar discectomies and microcervical foraminotomies was presented at annual meetings of the American Association of Neurological Surgeons and Congress of Neurological Surgeons in the 1970s and 1980s. An outsider to organized academic neurosurgery, Dг. Williams found his work was received cautiously and with significant skepticism. He found the orthopedic spine surgery community and journals more receptive, thus much of his earlier work was published in the orthopedic literature. This resulted in an orthopedic and neurosurgical following which was unique at that time. Dr. William's interesting career and contribution to spinal microsurgery is outlined, demonstrating the contributions to surgery, both neurological and orthopedic, that can be achieved by a neurosurgeon in private practice. N/A.

  3. Who Invented the Word Asteroid: William Herschel or Stephen Weston?

    Science.gov (United States)

    Cunningham, Clifford J.; Orchiston, Wayne

    2011-11-01

    William Herschel made the first serious study of 1 Ceres and 2 Pallas in the year 1802. He was moved by their dissimilarities to the other planets to coin a new term to distinguish them. For this purpose he enlisted the aid of his good friends William Watson and Sir Joseph Banks. Watson gave him a long list of possible names, which Herschel rejected. With a lifetime of experience classifying and naming newly found objects in nature, Banks became the man both Erasmus Darwin (in 1781) and William Herschel (in 1802) turned to for sage advice in developing a new descriptive language. In the case of Ceres and Pallas, Banks turned the task over to his friend, the noted philologist Stephen Weston, FRS. It has recently been stated by a noted British historian that it was Weston - not Herschel - who coined the term 'asteroid' to collectively describe Ceres and Pallas. This claim is investigated, and parallels are drawn in the use of neologism in astronomy and botany.

  4. Explicit Oral Narrative Intervention for Students with Williams Syndrome

    Directory of Open Access Journals (Sweden)

    Eliseo Diez-Itza

    2018-01-01

    Full Text Available Narrative skills play a crucial role in organizing experience, facilitating social interaction and building academic discourse and literacy. They are at the interface of cognitive, social, and linguistic abilities related to school engagement. Despite their relative strengths in social and grammatical skills, students with Williams syndrome (WS do not show parallel cognitive and pragmatic performance in narrative generation tasks. The aim of the present study was to assess retelling of a TV cartoon tale and the effect of an individualized explicit instruction of the narrative structure. Participants included eight students with WS who attended different special education levels. Narratives were elicited in two sessions (pre and post intervention, and were transcribed, coded and analyzed using the tools of the CHILDES Project. Narratives were coded for productivity and complexity at the microstructure and macrostructure levels. Microstructure productivity (i.e., length of narratives included number of utterances, clauses, and tokens. Microstructure complexity included mean length of utterances, lexical diversity and use of discourse markers as cohesive devices. Narrative macrostructure was assessed for textual coherence through the Pragmatic Evaluation Protocol for Speech Corpora (PREP-CORP. Macrostructure productivity and complexity included, respectively, the recall and sequential order of scenarios, episodes, events and characters. A total of four intervention sessions, lasting approximately 20 min, were delivered individually once a week. This brief intervention addressed explicit instruction about the narrative structure and the use of specific discourse markers to improve cohesion of story retellings. Intervention strategies included verbal scaffolding and modeling, conversational context for retelling the story and visual support with pictures printed from the cartoon. Results showed significant changes in WS students’ retelling of the

  5. Explicit Oral Narrative Intervention for Students with Williams Syndrome

    Science.gov (United States)

    Diez-Itza, Eliseo; Martínez, Verónica; Pérez, Vanesa; Fernández-Urquiza, Maite

    2018-01-01

    Narrative skills play a crucial role in organizing experience, facilitating social interaction and building academic discourse and literacy. They are at the interface of cognitive, social, and linguistic abilities related to school engagement. Despite their relative strengths in social and grammatical skills, students with Williams syndrome (WS) do not show parallel cognitive and pragmatic performance in narrative generation tasks. The aim of the present study was to assess retelling of a TV cartoon tale and the effect of an individualized explicit instruction of the narrative structure. Participants included eight students with WS who attended different special education levels. Narratives were elicited in two sessions (pre and post intervention), and were transcribed, coded and analyzed using the tools of the CHILDES Project. Narratives were coded for productivity and complexity at the microstructure and macrostructure levels. Microstructure productivity (i.e., length of narratives) included number of utterances, clauses, and tokens. Microstructure complexity included mean length of utterances, lexical diversity and use of discourse markers as cohesive devices. Narrative macrostructure was assessed for textual coherence through the Pragmatic Evaluation Protocol for Speech Corpora (PREP-CORP). Macrostructure productivity and complexity included, respectively, the recall and sequential order of scenarios, episodes, events and characters. A total of four intervention sessions, lasting approximately 20 min, were delivered individually once a week. This brief intervention addressed explicit instruction about the narrative structure and the use of specific discourse markers to improve cohesion of story retellings. Intervention strategies included verbal scaffolding and modeling, conversational context for retelling the story and visual support with pictures printed from the cartoon. Results showed significant changes in WS students’ retelling of the story, both at

  6. On Reading Poems: Visual & Verbal Icons in William Carlos Williams' «Landscape With The Fall Of Icarus»

    Directory of Open Access Journals (Sweden)

    Irene R. Fairley

    1981-09-01

    Full Text Available Williams' admiration for Brueghel's landscape is coded in structural and stylistic correspondences between the poem and the painting. Structures in the poem have effects analogous to the use of devices of color, line, foregrounding in the painting. The poem, like the painting, presents a «neutral» scene but subtly insures the reader's involvement. Further, Williams draws a visual statement so that graphic features suggest a global image isomorphic with the motif of descent. Features of the poem, such as line and clause length, syntactic construction, semantic coherence, are discussed as factors that contribute to rapid glancing and increase readability. A study of readers shows their sensitivity to graphic features including the poem's shape, and corroborates the importance of stylistic features.

  7. Dreamers in dialogue: evolution, sex and gender in the utopian visions of William Morris and William Henry Hudson

    Directory of Open Access Journals (Sweden)

    Caterina Novák

    2013-12-01

    Full Text Available The aim of this article is to explore the parallels between two late-nineteenth-century utopias,William Henry Hudsons A Crystal Age (1882 and William Morriss News from Nowhere (1891. Itaims to explore how these two works respond to the transition from a kinetic to a static conception ofutopia that under pressure from evolutionary and feminist discourses took place during the period.Particular focus lies on the way in which this is negotiated through the depiction of evolution, sexuality,and gender roles in the respective novels, and how the depiction of these disruptive elements may workas a means of ensuring the readers active engagement in political, intellectual and emotional terms.

  8. Normality of Residuals Is a Continuous Variable, and Does Seem to Influence the Trustworthiness of Confidence Intervals: A Response to, and Appreciation of, Williams, Grajales, and Kurkiewicz (2013)

    Science.gov (United States)

    Osborne, Jason W.

    2013-01-01

    Osborne and Waters (2002) focused on checking some of the assumptions of multiple linear regression. In a critique of that paper, Williams, Grajales, and Kurkiewicz correctly clarify that regression models estimated using ordinary least squares require the assumption of normally distributed errors, but not the assumption of normally distributed…

  9. Obituary: William Merz Sinton, 1925-2004

    Science.gov (United States)

    Spencer, John Robert

    2004-12-01

    occasions. In 1993 he was diagnosed with ALS (Lou Gehrig's disease), and was confined to a wheelchair shortly afterwards, but he continued to attend scientific meetings, and to contribute to Lowell Observatory as a member of its Advisory Board, till shortly before his death. In 2002 he published an autobiography, I Choose to Live, which described his life and his battle with ALS. Because he could no longer use a keyboard he wrote the entire book using voice-recognition software- a testament to his determination to keep as active and productive as possible despite the encroachments of the disease.We remember Bill as a warm, gentle, and enthusiastic man with an encyclopedic knowledge of all things infrared. He had a love of mechanical gadgets of all types, whether he was designing plumbing for a He3 cooled germanium bolometer or for a model steam engine. He is greatly missed by his family, friends, and former colleagues. Within two weeks of Bill's death came the announcement that CH4 gas had been discovered on Mars by the Mars Express spacecraft, confirming similar results from ground-based telescopes. The methane, touted as possible evidence for extant Martian life, was discovered via its 3.3-micron C-H stretch band. This is essentially the same vibrational transition, potentially carrying the same hints of living Martian organisms, which Bill thought he had seen on Mars 45 years earlier. So while Bill's initial conclusion that Mars is covered with extensive vegetation turned out to be wrong, his insight that the 3-micron region, with its telltale signature of carbon-hydrogen bonds, was the best place to search for evidence of life on our sister world, may have been right all along.

  10. Evolving the Topology of Hidden Markov Models using Evolutionary Algorithms

    DEFF Research Database (Denmark)

    Thomsen, Réne

    2002-01-01

    Hidden Markov models (HMM) are widely used for speech recognition and have recently gained a lot of attention in the bioinformatics community, because of their ability to capture the information buried in biological sequences. Usually, heuristic algorithms such as Baum-Welch are used to estimate ...

  11. The other Dr Hooker: William Dawson Hooker (1816-40).

    Science.gov (United States)

    Lambert, Harold

    2011-11-01

    William Hooker and his son Joseph were famous as botanists and as the creators of the Royal Botanic Gardens in Kew. Joseph was famous also as the friend and mentor of Charles Darwin. But there was another brother, a little older than Joseph, also a doctor and naturalist. He went to Jamaica in the interests of his health and soon died there of yellow fever. His life was short and tragic with a medical conundrum at its end but its story also illustrates many of the beliefs and concerns that preoccupied doctors in this early Victorian era. It also illustrates the close relationship between medicine and botany that prevailed then.

  12. Categories are alive: interview with Brackette F. Williams

    OpenAIRE

    Durão, Susana; Bastos, Cristiana; Williams, Brackette F.

    2013-01-01

    Brackette F. Williams is an American anthropologist and a Senior Justice ­Advocate, currently an associate professor of Cultural Anthropology at the University of ­Arizona. She studied at the University of Cornell, the University of Arizona, and received her doctorate from Johns Hopkins University. Her work interweaves ­matters of race, gender, class, ideology and politics in a unique manner – as seen in the article “A class act: Anthropology and the race to nation across ethnic terrain” (Ann...

  13. [Sir William Richard Gowers: author of the "bible of neurology"].

    Science.gov (United States)

    Hirose, Genjiro

    2014-11-01

    William Richard Gowers is one of the great pioneers in neurology and the author of the well-known neurology textbook, "A Manual of Diseases of the Nervous System." His concepts of neurology are based on meticulously and carefully accumulated knowledge of history, observations, and neurological examinations of patients with various neurological diseases. He is not only a great neurologist but also a great teacher who loves teaching students and physicians through well-prepared lectures. We can glean the essence of the field of neurology through his life story and numerous writings concerning neurological diseases.

  14. Pulmonary Arterial Stent Implantation in an Adult with Williams Syndrome

    International Nuclear Information System (INIS)

    Reesink, Herre J.; Henneman, Onno D. F.; Delden, Otto M. van; Biervliet, Jules D.; Kloek, Jaap J.; Reekers, Jim A.; Bresser, Paul

    2007-01-01

    We report a 38-year-old patient who presented with pulmonary hypertension and right ventricular dysfunction due to pulmonary artery stenoses as a manifestation of Williams syndrome, mimicking chronic thromboembolic pulmonary hypertension. The patient was treated with balloon angioplasty and stent implantation. Short-term follow-up showed a good clinical result with excellent patency of the stents but early restenosis of the segments in which only balloon angioplasty was performed. These stenoses were subsequently also treated successfully by stent implantation. Stent patency was observed 3 years after the first procedure

  15. Early career researchers: an interview with Caroline Williams.

    Science.gov (United States)

    2017-06-15

    Caroline Williams is an Assistant Professor at the University of California, Berkeley, USA, where she studies evolution of metabolic physiology in ectotherms. She grew up in New Zealand, where she received Bachelor's and Master's degrees in Zoology from the University of Otago in Dunedin. After travelling and working in Asia, she moved to Western University, Canada, for her PhD in the laboratory of Brent Sinclair, before joining Dan Hahn at the University of Florida as a postdoctoral research fellow. In 2010 she received the Scholander Award from the American Physiological Society. © 2017. Published by The Company of Biologists Ltd.

  16. COMIDA, MUJERES Y PODER EN LA OBRA DE TENNESSEE WILLIAMS

    OpenAIRE

    Torres Zúñiga, Laura

    2013-01-01

    La comida es un código semiótico que trasciende lo biológico y se integra en lo cultural –las normas, restricciones y tradiciones culinarias son indicativas de las relaciones establecidas entre los miembros de una comunidad. En este trabajo se revisan diferentes ejemplos de referencias alimenticias en las obras del dramaturgo estadounidense Tennessee Williams para descubrir cómo los personajes femeninos más indomables –especialmente en sus relatos– hacen uso de la comida como herr...

  17. Dr. William Thornton's views on sleep, dreams, and resuscitation.

    Science.gov (United States)

    Paulson, George

    2009-01-01

    William Thornton, MD, was a polymath who designed the Capitol of the U.S. Capital and the Octagon House, present home of the American Institute of Architecture. He was the founding director of the U.S. Patent Office. His collected papers, which are now preserved at the U.S. Library of Congress, though pruned by the wife who lived almost 40 years after him, are extensive and include comments on science, education, slavery, and politics. His views on sleep and dreaming and his concepts of resuscitation are reviewed as the opinions of an educated man early in the nineteenth century.

  18. Unravelling starlight: William and Margaret Huggins and the rise of the new astronomy

    National Research Council Canada - National Science Library

    Becker, Barbara J

    2011-01-01

    ...). A pioneer in adapting the spectroscope to new astronomical purposes, William Huggins rose to scientific prominence in London and transformed professional astronomy to become a principal founder...

  19. Face processing in Williams syndrome is already atypical in infancy

    Directory of Open Access Journals (Sweden)

    Dean eD'Souza

    2015-06-01

    Full Text Available Face processing is a crucial socio-cognitive ability. Is it acquired progressively or does it constitute an innately-specified, face-processing module? The latter would be supported if some individuals with seriously impaired intelligence nonetheless showed intact face-processing abilities. Some theorists claim that Williams syndrome (WS provides such evidence since, despite IQs in the 50s, adolescents/adults with WS score in the normal range on standardised face-processing tests. Others argue that atypical neural and cognitive processes underlie WS face-processing proficiencies. But what about infants with WS? Do they start with typical face-processing abilities, with atypicality developing later, or are atypicalities already evident in infancy? We used an infant familiarisation/novelty design and compared infants with WS to healthy controls as well as to a group of infants with DS matched on both mental and chronological age. Participants were familiarised with a schematic face, after which they saw a novel face in which either the features (eye shape were changed or just the configuration of the original features. Configural changes were processed successfully by controls, but not by infants with WS who were only sensitive to featural changes and who showed syndrome-specific profiles different from infants with the other neurodevelopmental disorder. Our findings indicate that theorists can no longer use the case of Williams syndrome to support claims that evolution has endowed the human brain with an independent face-processing module.

  20. Sir William Osler's speech at Troy: a Trojan horse?

    Science.gov (United States)

    Moran, Michael E

    2012-01-01

    Troy, New York, is a city of 55,000 people in upstate New York located along the Hudson River. A city of surprisingly rich cultural heritage, it was the home of New York state's first hospital outside New York City. The 50th anniversary celebration of Troy's hospital brought William Osler to the city as the keynote speaker. This speech, delivered on November 28, 1900, is one of Sir William's less well known addresses. Osler began his comments with Sir Thomas More's Utopia and talked at length about the hospital, its obligations, the influences it has upon the community, and the role of physicians and surgeons. He broached one of his old saws, the salary of attending physicians and their needed role in hospital management. His words were published in the diamond jubilee's records, but the hospital did not outlive its prominent guest professor, and it closed its doors in 1914. Just like the great historical city of Troy, New York's own Troy was on the brink of decline, and its hospital would be the first fatality. Therefore, it is almost prescient that the words of Osler, taken into historical context juxtaposed against the socioeconomic forces at work, are akin to the Greek's offering of a wooden edifice to end the Trojan War.

  1. William John Burchell: The multi-skilled polymath

    Directory of Open Access Journals (Sweden)

    Roger Stewart

    2012-10-01

    Full Text Available On the bicentenary of William John Burchell’s sojourn and journey in southern Africa, we review his contribution to science in the region. In November 1810, Burchell arrived in Cape Town and, in mid-1811, he set off on a 4-year, 7000-km journey of scientific exploration. When he returned to Cape Town in April 1815, he had amassed 63 000 specimens and 500 drawings. Burchell is remembered mainly for his contributions to descriptive and philosophical aspects of natural history of the country. He is less well known for some significant and novel contributions to the earth sciences, the social sciences and even astronomy. Burchell’s observations in physical geography and geology and his contribution to cartography have received little attention. In natural history, some of his views were prescient of the concepts of evolution and holism. In the social sciences, he provided unique ethnographic descriptions, developed an orthography of two indigenous languages and produced drawings that have attracted international research. William John Burchell is worthy of our memory.

  2. William James, Nitrous Oxide, and the Anaesthetic Revelation.

    Science.gov (United States)

    Moon, Jane S; Kuza, Catherine M; Desai, Manisha S

    2018-01-01

    William James greatly influenced the fields of psychology, philosophy, and religion during the late 19 th and early 20 th centuries. This was the era of Modernism, a time when many writers rejected the certainty of Enlightenment ideals. Positivism, which rose to prominence in the early 19th century, had emphasized physical phenomena, empirical evidence, and the scientific method. Darwin's On the Origin of Species (1859), with its theory of natural selection, provided an explanation for the evolution of species apart from a divine Creator. Within this context, William James served as a "mediator between scientific agnosticism and the religious view of the world." James' own experience inhaling nitrous oxide played an important role in shaping his views. For James, the use of nitrous oxide served a key role in elucidating some of his most central ideas: 1) the value of religion, and the emphasis on mysticism and revelation (as opposed to theology and doctrine) as religion's foundation; 2) the universe as pluralistic (as opposed to absolutist, constant, eternal), driven by chance, experience, and change. Copyright © 2017 Elsevier Inc. All rights reserved.

  3. A Ffowcs Williams and Hawkings formulation for hydroacoustic analysis of propeller sheet cavitation

    Science.gov (United States)

    Testa, C.; Ianniello, S.; Salvatore, F.

    2018-01-01

    A novel hydroacoustic formulation for the prediction of tonal noise emitted by marine propellers in presence of unsteady sheet cavitation, is presented. The approach is based on the standard Ffowcs Williams and Hawkings equation and the use of transpiration (velocity and acceleration) terms, accounting for the time evolution of the vapour cavity attached on the blade surface. Drawbacks and potentialities of the method are tested on a marine propeller operating in a nonhomogeneous onset flow, by exploiting the hydrodynamic data from a potential-based panel method equipped with a sheet cavitation model and comparing the noise predictions with those carried out by an alternative numerical approach, documented in literature. It is shown that the proposed formulation yields a one-to-one correlation between emitted noise and sheet cavitation dynamics, carrying out accurate predictions in terms of noise magnitude and directivity.

  4. John Dalton and the London atomists: William and Bryan Higgins, William Austin, and new Daltonian doubts about the origin of the atomic theory

    Science.gov (United States)

    Grossman, Mark I.

    2014-01-01

    Most historians have ruled out the possibility that John Dalton was influenced by the theories of atomists William and Bryan Higgins, as well as William Austin, in developing his first table of atomic weights on 6 September 1803. I review and evaluate the case to be made for the influence of each scientist on Dalton. Contrary to prevailing views, I raise new Daltonian doubts, especially for Bryan Higgins.

  5. Inventing Orientation and Mobility Techniques and Teaching Methods: A Conversation with Russell Williams (Part 2)

    Science.gov (United States)

    Welsh, Rachard L.

    2005-01-01

    This is the final part of the adaptation from my on-stage conversation with Russell Williams at the 1998 International Mobility conference in Atlanta, GA, which attempted to highlight Williams's contributions to the progression of orientation and mobility from the Army's immediate response to the service men and women who lost their sight during…

  6. 77 FR 63308 - J. William Foley Incorporated v. United Illuminating Company; Notice of Complaint

    Science.gov (United States)

    2012-10-16

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EL12-106-000] J. William Foley Incorporated v. United Illuminating Company; Notice of Complaint Take notice that on October 5...) and 825(e), J. William Foley Incorporated (Complainant) filed a formal complaint against United...

  7. 78 FR 50335 - Double Hull Tanker Escorts on the Waters of Prince William Sound, Alaska

    Science.gov (United States)

    2013-08-19

    ...-AB96 Double Hull Tanker Escorts on the Waters of Prince William Sound, Alaska AGENCY: Coast Guard, DHS... requirements for certain tankers operating on the waters of Prince William Sound, Alaska (PWS). This interim... National Technology Transfer and Advancement Act OPA 90 Oil Pollution Act of 1990 (Pub. L. 101-380, 104...

  8. Auditory Attraction: Activation of Visual Cortex by Music and Sound in Williams Syndrome

    Science.gov (United States)

    Thornton-Wells, Tricia A.; Cannistraci, Christopher J.; Anderson, Adam W.; Kim, Chai-Youn; Eapen, Mariam; Gore, John C.; Blake, Randolph; Dykens, Elisabeth M.

    2010-01-01

    Williams syndrome is a genetic neurodevelopmental disorder with a distinctive phenotype, including cognitive-linguistic features, nonsocial anxiety, and a strong attraction to music. We performed functional MRI studies examining brain responses to musical and other types of auditory stimuli in young adults with Williams syndrome and typically…

  9. Music and Anxiety in Williams Syndrome: A Harmonious or Discordant Relationship?

    Science.gov (United States)

    Dykens, Elisabeth M.; Rosner, Beth A.; Ly, Tran; Sagun, Jaclyn

    2005-01-01

    In this two-part study, we assessed musical involvements in two samples of persons with Williams syndrome compared to others with mental retardation and also related musicality to anxiety and fears in Study 2. Relative to others with mental retardation, those with Williams syndrome were more likely to take music lessons, play an instrument, and…

  10. 34 CFR 663.22 - How does the J. William Fulbright Foreign Scholarship Board select fellows?

    Science.gov (United States)

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false How does the J. William Fulbright Foreign Scholarship Board select fellows? 663.22 Section 663.22 Education Regulations of the Offices of the Department of... Scholarship Board select fellows? The J. William Fulbright Foreign Scholarship Board selects fellows on the...

  11. 34 CFR 662.22 - How does the J. William Fulbright Foreign Scholarship Board select fellows?

    Science.gov (United States)

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false How does the J. William Fulbright Foreign Scholarship Board select fellows? 662.22 Section 662.22 Education Regulations of the Offices of the Department of... Foreign Scholarship Board select fellows? (a) The J. William Fulbright Foreign Scholarship Board selects...

  12. Anxiety and Repetitive Behaviours in Autism Spectrum Disorders and Williams Syndrome: A Cross-Syndrome Comparison

    Science.gov (United States)

    Rodgers, Jacqui; Riby, Deborah M.; Janes, Emily; Connolly, Brenda; McConachie, Helen

    2012-01-01

    Children with Autism Spectrum Disorder or Williams syndrome are vulnerable to anxiety. The factors that contribute to this risk remain unclear. This study compared anxiety in autism spectrum disorder and Williams Syndrome and examined the relationship between repetitive behaviours and anxiety. Thirty-four children with autism and twenty children…

  13. Brief Report: Developing Spatial Frequency Biases for Face Recognition in Autism and Williams Syndrome

    Science.gov (United States)

    Leonard, Hayley C.; Annaz, Dagmara; Karmiloff-Smith, Annette; Johnson, Mark H.

    2011-01-01

    The current study investigated whether contrasting face recognition abilities in autism and Williams syndrome could be explained by different spatial frequency biases over developmental time. Typically-developing children and groups with Williams syndrome and autism were asked to recognise faces in which low, middle and high spatial frequency…

  14. Valuing Higher Education: An Appreciation of the Work of Gareth Williams

    Science.gov (United States)

    Barnett, Ronald, Ed.; Temple, Paul, Ed.; Scott, Peter, Ed.

    2016-01-01

    In "Valuing Higher Education," leading international analysts examine Gareth Williams's contribution to shaping our thinking about the economics of higher education in essays that are a testimony to Williams's conception that the field cannot be properly understood unless viewed alongside social policy, changes in knowledge production,…

  15. 33 CFR 164.43 - Automatic Identification System Shipborne Equipment-Prince William Sound.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Automatic Identification System Shipborne Equipment-Prince William Sound. 164.43 Section 164.43 Navigation and Navigable Waters COAST GUARD... Automatic Identification System Shipborne Equipment—Prince William Sound. (a) Until December 31, 2004, each...

  16. Within-Domain Dissociations in Williams Syndrome: A Window on the Normal Mind.

    Science.gov (United States)

    Karmiloff-Smith, Annette; And Others

    This poster reports on a study attempting to distinguish between the influences of domain-specific and domain-general developmental mechanisms in subjects with Williams Syndrome (a genetic defect resulting in mental retardation). Subjects included 10 monolingual French-speaking subjects (ages 9-21) with Williams syndrome and 10 monolingual…

  17. WE-G-213-00: History Symposium: Radiological Physics Pioneers: Roentgen and the AAPM Award Eponyms - William Coolidge, Edith Quimby, and Marvin Williams - Who Were They and What Did They Do?

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2015-06-15

    Roentgen and the Birth of Modern Medical Physics – Perry Sprawls Wilhelm Roentgen is well known for his discovery of x-radiation. What is less known and appreciated is his intensive research following the discovery to determine the characteristics of the “new kind of radiation” and demonstrate its great value for medical purposes. In this presentation we will imagine ourselves in Roentgen’s mind and follow his thinking, including questions and doubts, as he designs and conducts a series of innovative experiments that provided the foundation for the rapid growth of medical physics. Learning Objectives: Become familiar with the personal characteristics and work of Prof. Roentgen that establishes him as an inspiring model for the medical physics profession. Observe the thought process and experiments that determined and demonstrated the comprehensive characteristics of x-radiation. The AAPM Award Eponyms: William D. Coolidge, Edith H. Quimby, and Marvin M.D. Williams - Who were they and what did they do? – Lawrence N. Rothenberg William David Coolidge (1873–1975) William Coolidge was born in Hudson, NY in 1873. He obtained his BS at the Massacusetts Institute of Technology in 1896. Coolidge then went to the University of Leipzig, Germany for graduate study with physicists Paul Drude and Gustave Wiedemann and received a Ph.D. in 1899. While in Germany he met Wilhelm Roentgen. Coolidge returned to the US to teach at MIT where he was associated with Arthur A. Noyes of the Chemistry Department, working on the electrical conductivity of aqueous solutions. Willis R. Whitney, under whom Coolidge had worked before going to Germany, became head of the newly formed General Electric Research Laboratory and he invited Coolidge to work with him. In 1905, Coolidge joined the staff of the GE laboratory and was associated with it for the remainder of his life. He developed ductile tungsten filaments to replace fragile carbon filaments as the material for electric light

  18. WE-G-213-02: The AAPM Award Eponyms: William D. Coolidge, Edith H. Quimby, and Marvin M.D. Williams - Who Were They and What Did They Do?

    Energy Technology Data Exchange (ETDEWEB)

    Rothenberg, L. [Memorial Sloan-Kettering Cancer Center (United States)

    2015-06-15

    Roentgen and the Birth of Modern Medical Physics – Perry Sprawls Wilhelm Roentgen is well known for his discovery of x-radiation. What is less known and appreciated is his intensive research following the discovery to determine the characteristics of the “new kind of radiation” and demonstrate its great value for medical purposes. In this presentation we will imagine ourselves in Roentgen’s mind and follow his thinking, including questions and doubts, as he designs and conducts a series of innovative experiments that provided the foundation for the rapid growth of medical physics. Learning Objectives: Become familiar with the personal characteristics and work of Prof. Roentgen that establishes him as an inspiring model for the medical physics profession. Observe the thought process and experiments that determined and demonstrated the comprehensive characteristics of x-radiation. The AAPM Award Eponyms: William D. Coolidge, Edith H. Quimby, and Marvin M.D. Williams - Who were they and what did they do? – Lawrence N. Rothenberg William David Coolidge (1873–1975) William Coolidge was born in Hudson, NY in 1873. He obtained his BS at the Massacusetts Institute of Technology in 1896. Coolidge then went to the University of Leipzig, Germany for graduate study with physicists Paul Drude and Gustave Wiedemann and received a Ph.D. in 1899. While in Germany he met Wilhelm Roentgen. Coolidge returned to the US to teach at MIT where he was associated with Arthur A. Noyes of the Chemistry Department, working on the electrical conductivity of aqueous solutions. Willis R. Whitney, under whom Coolidge had worked before going to Germany, became head of the newly formed General Electric Research Laboratory and he invited Coolidge to work with him. In 1905, Coolidge joined the staff of the GE laboratory and was associated with it for the remainder of his life. He developed ductile tungsten filaments to replace fragile carbon filaments as the material for electric light

  19. WE-G-213-02: The AAPM Award Eponyms: William D. Coolidge, Edith H. Quimby, and Marvin M.D. Williams - Who Were They and What Did They Do?

    International Nuclear Information System (INIS)

    Rothenberg, L.

    2015-01-01

    Roentgen and the Birth of Modern Medical Physics – Perry Sprawls Wilhelm Roentgen is well known for his discovery of x-radiation. What is less known and appreciated is his intensive research following the discovery to determine the characteristics of the “new kind of radiation” and demonstrate its great value for medical purposes. In this presentation we will imagine ourselves in Roentgen’s mind and follow his thinking, including questions and doubts, as he designs and conducts a series of innovative experiments that provided the foundation for the rapid growth of medical physics. Learning Objectives: Become familiar with the personal characteristics and work of Prof. Roentgen that establishes him as an inspiring model for the medical physics profession. Observe the thought process and experiments that determined and demonstrated the comprehensive characteristics of x-radiation. The AAPM Award Eponyms: William D. Coolidge, Edith H. Quimby, and Marvin M.D. Williams - Who were they and what did they do? – Lawrence N. Rothenberg William David Coolidge (1873–1975) William Coolidge was born in Hudson, NY in 1873. He obtained his BS at the Massacusetts Institute of Technology in 1896. Coolidge then went to the University of Leipzig, Germany for graduate study with physicists Paul Drude and Gustave Wiedemann and received a Ph.D. in 1899. While in Germany he met Wilhelm Roentgen. Coolidge returned to the US to teach at MIT where he was associated with Arthur A. Noyes of the Chemistry Department, working on the electrical conductivity of aqueous solutions. Willis R. Whitney, under whom Coolidge had worked before going to Germany, became head of the newly formed General Electric Research Laboratory and he invited Coolidge to work with him. In 1905, Coolidge joined the staff of the GE laboratory and was associated with it for the remainder of his life. He developed ductile tungsten filaments to replace fragile carbon filaments as the material for electric light

  20. WE-G-213-00: History Symposium: Radiological Physics Pioneers: Roentgen and the AAPM Award Eponyms - William Coolidge, Edith Quimby, and Marvin Williams - Who Were They and What Did They Do?

    International Nuclear Information System (INIS)

    2015-01-01

    Roentgen and the Birth of Modern Medical Physics – Perry Sprawls Wilhelm Roentgen is well known for his discovery of x-radiation. What is less known and appreciated is his intensive research following the discovery to determine the characteristics of the “new kind of radiation” and demonstrate its great value for medical purposes. In this presentation we will imagine ourselves in Roentgen’s mind and follow his thinking, including questions and doubts, as he designs and conducts a series of innovative experiments that provided the foundation for the rapid growth of medical physics. Learning Objectives: Become familiar with the personal characteristics and work of Prof. Roentgen that establishes him as an inspiring model for the medical physics profession. Observe the thought process and experiments that determined and demonstrated the comprehensive characteristics of x-radiation. The AAPM Award Eponyms: William D. Coolidge, Edith H. Quimby, and Marvin M.D. Williams - Who were they and what did they do? – Lawrence N. Rothenberg William David Coolidge (1873–1975) William Coolidge was born in Hudson, NY in 1873. He obtained his BS at the Massacusetts Institute of Technology in 1896. Coolidge then went to the University of Leipzig, Germany for graduate study with physicists Paul Drude and Gustave Wiedemann and received a Ph.D. in 1899. While in Germany he met Wilhelm Roentgen. Coolidge returned to the US to teach at MIT where he was associated with Arthur A. Noyes of the Chemistry Department, working on the electrical conductivity of aqueous solutions. Willis R. Whitney, under whom Coolidge had worked before going to Germany, became head of the newly formed General Electric Research Laboratory and he invited Coolidge to work with him. In 1905, Coolidge joined the staff of the GE laboratory and was associated with it for the remainder of his life. He developed ductile tungsten filaments to replace fragile carbon filaments as the material for electric light

  1. A new case of keratoconus associated with Williams-Beuren syndrome.

    Science.gov (United States)

    Viana, Melissa Machado; Frasson, Maria; Leão, Letícia Lima; Stofanko, Martin; Gonçalves-Dornelas, Higgor; Cunha, Pricila da Silva; de Aguiar, Marcos José Burle

    2013-09-01

    Williams-Beuren syndrome is a multisystemic genetic disorder caused by a contiguous gene deletion at 7q11.23. Keratoconus is a complex disease and it is suspected to have a genetic origin, although the specific gene responsible for keratoconus has not been identified. Although there are several ocular features in Williams-Beuren syndrome, keratoconus is not regularly described as part of this syndrome. To report a new patient with keratoconus and Williams-Beuren syndrome. This is the third case of an association between Williams-Beuren syndrome and keratoconus. The authors believe that the Williams-Beuren syndrome chromosome region can be a possible target for further investigation as the genetic basis of keratoconus.

  2. Profiles in drug metabolism and toxicology: Richard Tecwyn Williams (1909-1979).

    Science.gov (United States)

    Jones, Alan Wayne

    2015-01-01

    This article pays homage to the life and work of a veritable pioneer in toxicology and drug metabolism, namely a Welshman, Richard Tecwyn Williams, FRS. Professor Williams, or RT as he was known, made major contributions to knowledge about the metabolism and toxicology of drugs and xenobiotics during a scientific career spanning nearly 50 years. Author or coauthor of close to 400 research articles and reviews, including a classic book, entitled Detoxication Mechanisms, Williams and his research school investigated virtually all aspects of drug metabolism, especially conjugations. In particular, the concepts of phase 1 and phase II metabolic pathways were introduced by Williams; the biliary excretion of drugs was extensively studied as were species differences in drug metabolism and detoxication. Besides investigating the metabolism of many pharmaceutical drugs, such as sulfonamides and thalidomide, Williams and his group investigated the disposition and fate in the body of organic pesticides and recreational drugs of abuse, such as amphetamine, methamphetamine and lysergic acid diethylamide (LSD).

  3. What motion is: William Neile and the laws of motion.

    Science.gov (United States)

    Kemeny, Max

    2017-07-01

    In 1668-1669 William Neile and John Wallis engaged in a protracted correspondence regarding the nature of motion. Neile was unhappy with the laws of motion that had been established by the Royal Society in three papers published in 1668, deeming them not explanations of motion at all, but mere descriptions. Neile insisted that science could not be informative without a discussion of causes, meaning that Wallis's purely kinematic account of collision could not be complete. Wallis, however, did not consider Neile's objections to his work to be serious. Rather than engage in a discussion of the proper place of natural philosophy in science, Wallis decided to show how Neile's preferred treatment of motion lead to absurd conclusions. This dispute is offered as a case study of dispute resolution within the early Royal Society.

  4. The Values of Masculinity in William Shakespeare’s Macbeth

    Directory of Open Access Journals (Sweden)

    Mafruha Ferdous

    2017-04-01

    Full Text Available The theme of gender plays a vital role in William Shakespeare’s famous political play Macbeth. From the very beginning of the play the dramatist focuses on the importance of masculinity in gaining power and authority. Lady Macbeth along with the three witches are as important characters as Macbeth. Because they influence Macbeth profoundly. And Shakespeare very carefully draws the character of Lady Macbeth who being a female sometimes exhibits more masculinity than Macbeth. Similarly is the case of the three witches. Though they look like women they are also bearded which prove the presence of masculinity in their nature. Throughout the play several times the exposition of masculinity is demanded from the character of Macbeth. So the value of masculinity plays an important part in the drama.

  5. Beat Perception and Sociability: Evidence from Williams Syndrome.

    Science.gov (United States)

    Lense, Miriam D; Dykens, Elisabeth M

    2016-01-01

    Beat perception in music has been proposed to be a human universal that may have its origins in adaptive processes involving temporal entrainment such as social communication and interaction. We examined beat perception skills in individuals with Williams syndrome (WS), a genetic, neurodevelopmental disorder. Musical interest and hypersociability are two prominent aspects of the WS phenotype although actual musical and social skills are variable. On a group level, beat and meter perception skills were poorer in WS than in age-matched peers though there was significant individual variability. Cognitive ability, sound processing style, and musical training predicted beat and meter perception performance in WS. Moreover, we found significant relationships between beat and meter perception and adaptive communication and socialization skills in WS. Results have implications for understanding the role of predictive timing in both music and social interactions in the general population, and suggest music as a promising avenue for addressing social communication difficulties in WS.

  6. William Whewell's philosophy of architecture and the historicization of biology.

    Science.gov (United States)

    Quinn, Aleta

    2016-10-01

    William Whewell's work on historical science has received some attention from historians and philosophers of science. Whewell's own work on the history of German Gothic church architecture has been touched on within the context of the history of architecture. To a large extent these discussions have been conducted separately. I argue that Whewell intended his work on Gothic architecture as an attempt to (help) found a science of historical architecture, as an exemplar of historical science. I proceed by analyzing the key features of Whewell's philosophy of historical science. I then show how his architectural history exemplifies this philosophy. Finally, I show how Whewell's philosophy of historical science matches some developments in a science (biological systematics) that, in the mid-to late-nineteenth century, came to be reinterpreted as a historical science. I comment briefly on Whewell as a potential influence on nineteenth century biology and in particular on Darwin. Copyright © 2016 Elsevier Ltd. All rights reserved.

  7. Mapping the Milky Way: William Herschel's Star Gages

    Science.gov (United States)

    Timberlake, Todd

    2013-01-01

    William Herschel (Fig. 1) is rightfully known as one of the greatest astronomers of all time. Born in Hanover (in modern Germany) in 1738, Herschel immigrated to England in 1757 and began a successful career as a professional musician. Later in life Herschel developed a strong interest in astronomy. He began making his own reflecting telescopes in 1774, and soon his telescopes were recognized as the finest in the world. It was through one of his homemade telescopes, a Newtonian reflector with a focal length of seven feet and an aperture of 6.2 inches, that Herschel first spotted the planet Uranus in 1781. The discovery of a new planet catapulted Herschel to fame and secured him a position as personal astronomer to King George III.

  8. Cardiac arrest related to anaesthesia in Williams-Beuren syndrome.

    Science.gov (United States)

    Lucena Delgado, J; Sanabria Carretero, P; Durán la Fuente, P; Gónzalez Rocafort, A; Castro Parga, L; Reinoso Barbero, F

    2017-12-12

    Williams-Beuren syndrome is the clinical manifestation of a congenital genetic disorder in the elastin gene, among others. There is a history of cardiac arrest refractory to resuscitation manoeuvres in anaesthesia. The incidence of myocardial ischaemia is high during anaesthetic induction, but there are patients who do not have this condition yet also have had very serious cardiac events, and issues that are still to be resolved. Case descriptions will enable the common pathophysiological factors to be defined, and decrease morbidity and mortality. We report the case of a 3-year-old boy with cardiac arrest at induction, rescued with circulatory assistance with extracorporeal membrane oxygenation and hypothermia induced for cerebral protection. Copyright © 2017 Sociedad Española de Anestesiología, Reanimación y Terapéutica del Dolor. Publicado por Elsevier España, S.L.U. All rights reserved.

  9. Charles William Lacaillade. Biologist, Parasitologist, Educator, and Mentor.

    Science.gov (United States)

    Imperato, Pascal James

    2017-02-01

    Charles William Lacaillade (1904-1978) was an eminent biologist in the middle decades of the twentieth century. He was born in Lawrence, Massachusetts of parents whose ancestors were French Canadians. His father, also named Charles William Lacaillade, was a dentist who graduated from Tufts University School of Dentistry in 1898. His mother, Elodia Eno, came from a family of very successful businessmen. Lacaillade was the third of six children. His two older brothers, Harold Carleton and Hector Eno, both graduated from the University of Louisville, School of Dentistry, while his younger brother, Lawrence, became a businessman. His sister, Luemma, married Dr. Henry Steadman, a veterinarian, while his youngest sister, Gloria, married a U.S. Army officer, Lieutenant Colonel Victor Anido. Lacaillade received his MS and PhD degrees in biology and zoology from Harvard University. He then became a fellow at The Rockefeller Institute for Medical Research. At both institutions, he studied under some of the most eminent biological scientists of the time. These included Rudolf W. Glaser, George Howard Parker, Theobald Smith, Carl TenBroeck, and William Morton Wheeler. At the Rockefeller Institute, he co-discovered the vector and mode of transmission of Eastern Equine Encephalomyelitis. This discovery, and the research he conducted with Rudolf W. Glaser, quickly established him as an outstanding biological researcher. However, a change in leadership at the Rockefeller Institute resulted in research priorities being given to the disciplines of general physiology, physical chemistry, and nutrition. This shift in the research agenda away from the biological sciences precluded career advancement at the Rockefeller Institute for post-doctoral fellows like Lacaillade. It was the height of the Great Depression, and even biologists with terminal doctoral degrees found it difficult to find positions. In 1935, Lacaillade accepted a position as an assistant in biology at St. John

  10. Hazen-Williams equation corrected for swine wastewater

    OpenAIRE

    Sampaio, Silvio C.; Cilene, Kátia; Boas, Márcio A. Vilas; Queiroz, Manoel M. F. de; Gomes, Benedito M.; Fazolo, Ajadir

    2007-01-01

    O objetivo do trabalho foi avaliar a perda de carga em tubulações comerciais de aço zincado, ferro galvanizado e PVC, com diferentes diâmetros, com o intuito de determinar fatores de correção para a equação de Hazen-Williams em função da concentração de sólidos totais, em águas residuárias oriundas da suinocultura. Os resultados mostraram que a perda de carga possui comportamento linear em função da concentração de sólidos totais da água residuária proveniente da suinocultura; as perdas de ca...

  11. William E. Edmonston, Jr.: Editor, 1968-1976.

    Science.gov (United States)

    Kihlstrom, John F; Frischholz, Edward J

    2010-10-01

    This article is part of an occasional series profiling editors of the American Journal of Clinical Hypnosis (AJCH). William E. Edmonston was the second editor, succeeding Milton H. Erickson. His research focused on the use of conditioning paradigms and psychophysiological measures to explore a wide variety of hypnotic phenomena, leading to a "neo-Pavlovian" theory of neutral hypnosis as physiological relaxation (anesis). A longtime professor of psychology at Colgate University, he created an interdisciplinary undergraduate major in neuroscience, and was named New York State College Professor of the Year in 1988. He gave the Journal a new look, and a greater balance of clinical and experimental papers. The article also provides background on George Barton Cutten, George H. Estabrooks, and Frank A. Pattie, pioneers of hypnosis who were linked to Edmonston.

  12. Syntax in Spanish-speaking children with Williams syndrome.

    Science.gov (United States)

    Benítez-Burraco, Antonio; Garayzábal, Elena; Cuetos, Fernando

    2016-01-01

    The syntactic skills of Spanish-speaking children with Williams syndrome (WS) were assessed in different areas (phrase structure, recursion, and bound anaphora). Children were compared to typically-developing peers matched either in chronological age (CA-TD) or in verbal age (VA-TD). In all tasks children with WS performed significantly worse than CA-TD children, but similarly to VA-TD children. However, significant differences were observed in specific domains, particularly regarding sentences with cross-serial dependencies. At the same time, children with WS were less sensitive to syntactic constraints and exhibited a poorer knowledge of some functional words (specifically, of nonreflexive pronouns). A processing bottleneck or a computational constraint may account for this outcome. Copyright © 2016 Elsevier Inc. All rights reserved.

  13. Dissociating intuitive physics from intuitive psychology: Evidence from Williams syndrome.

    Science.gov (United States)

    Kamps, Frederik S; Julian, Joshua B; Battaglia, Peter; Landau, Barbara; Kanwisher, Nancy; Dilks, Daniel D

    2017-11-01

    Prior work suggests that our understanding of how things work ("intuitive physics") and how people work ("intuitive psychology") are distinct domains of human cognition. Here we directly test the dissociability of these two domains by investigating knowledge of intuitive physics and intuitive psychology in adults with Williams syndrome (WS) - a genetic developmental disorder characterized by severely impaired spatial cognition, but relatively spared social cognition. WS adults and mental-age matched (MA) controls completed an intuitive physics task and an intuitive psychology task. If intuitive physics is a distinct domain (from intuitive psychology), then we should observe differential impairment on the physics task for individuals with WS compared to MA controls. Indeed, adults with WS performed significantly worse on the intuitive physics than the intuitive psychology task, relative to controls. These results support the hypothesis that knowledge of the physical world can be disrupted independently from knowledge of the social world. Copyright © 2017 Elsevier B.V. All rights reserved.

  14. 77 FR 66841 - The Sherwin-Williams Company; Analysis of Proposed Consent Order To Aid Public Comment

    Science.gov (United States)

    2012-11-07

    ... FEDERAL TRADE COMMISSION [File No. 112 3198] The Sherwin-Williams Company; Analysis of Proposed... for Comment part of the SUPPLEMENTARY INFORMATION section below. Write ``Sherwin-Williams, File No... comment, we must receive it on or before November 26, 2012. Write ``Sherwin-Williams, File No. 112 3198...

  15. 77 FR 17568 - Notice of Receipt of Petition for Decision That Nonconforming 2005 Ifor Williams LM85G Trailers...

    Science.gov (United States)

    2012-03-26

    ...-0030, Notice 1] Notice of Receipt of Petition for Decision That Nonconforming 2005 Ifor Williams LM85G... Safety Administration (NHTSA) of a petition for a decision that 2005 Ifor Williams LM85G trailers that... whether nonconforming 2005 Ifor Williams LM85G trailers are eligible for importation into the United...

  16. Early Science Results from the Williams College Eclipse Expedition

    Science.gov (United States)

    Pasachoff, Jay M.; Person, Michael J.; Dantowitz, Ron; Lockwood, Christian A.; Nagle-McNaughton, Tim; Meadors, Erin N.; Perez, Cielo C.; Marti, Connor J.; Yu, Ross; Rosseau, Brendan; Daly, Declan M.; Ide, Charles A.; Davis, Allen B.; Lu, Muzhou; Sliski, David; Seiradakis, John; Voulgaris, Aris; Rusin, Vojtech; Peñaloza-Murillo, Marcos A.; Roman, Michael; Seaton, Daniel B.; Steele, Amy; Lee, Duane M.; Freeman, Marcus J.

    2018-01-01

    We describe our first cut of data reduction on a wide variety of observations of the solar corona and of the effect of the penumbra and umbra on the terrestrial atmosphere, carried out from our eclipse site on the campus of Willamette University in Salem, Oregon. Our team of faculty, undergraduate students, graduate students, and other colleagues observed the eclipse, taking images and spectra with a variety of sensors and telescopes. Equipment included frame-transfer cameras observing at 3 Hz in 0.3 nm filters at the coronal green and red lines to measure the power spectrum of oscillations in coronal loops or elsewhere in the lower corona; 3 spectrographs; a variety of telescopes and telephotos for white-light imaging; a double Lyot system tuned at Fe XIV 530.3 nm (FWHM 0.4 nm) and Fe X 637.4 nm (FWHM 0.5 nm); and a weather station to record changes in the terrestrial atmosphere. We are comparing our observations with predictions based on the previous mapping of the photospheric magnetic field, and preparing wide-field complete coronal imaging incorporating NOAA/NASA GOES-16 SUVI and NRL/NASA/LASCO for the corona outside our own images (which extend, given the completely clear skies we had, at least 4 solar radii), and NASA SDO/AIA and NOAA/NASA GOES-16 SUVI for the solar disk. One of our early composites appeared as Astronomy Picture of the Day for September 27: https://apod.nasa.gov/apod/ap170927.htmlOur expedition was supported in large part by grants from the Committee for Research and Exploration of the National Geographic Society and from the Solar Terrestrial Program of the Atmospheric and Geospace Sciences Division of the National Science Foundation, with additional student support from the STP/AGS of NSF, the NASA Massachusetts Space Grant Consortium, the Sigma Xi honorary scientific society, the Clare Booth Luce Foundation studentship and the Freeman Foote Expeditionary Fund at Williams College, other Williams College funds, and U. Pennsylvania funds.

  17. William Henry Broadbent (1835-1907) as a neurologist.

    Science.gov (United States)

    Eadie, Mervyn

    2015-01-01

    By the end of his career, Sir William Broadbent (1835-1907) had become an eminent London general physician who had been appointed Physician-in-Ordinary to King Edward VII and to the Prince of Wales. Previously he had been Physician-in-Extraordinary to Queen Victoria. At earlier stages in his professional life, he had played a significant role in the development of clinical neurology in Victorian-era Britain. In 1866, he had enunciated a principle (Broadbent's hypothesis) that for the first time satisfactorily accounted for the mechanisms by which the trunk and bulbar muscles and the upper face were spared in hemiplegia. He had also carried out original investigations into the distribution of fiber tracts in the human cerebral hemispheres. At intervals over the years, he published on aspects of aphasia and developed a rather complicated though logical conceptual schema of the presumed anatomical background to the process of speech, based on clinic-pathological correlations. His role in all this neurological research and his other contributions on subjects such as neurosyphilis have largely been forgotten by subsequent generations.

  18. In Search of William Gascoigne Seventeenth Century Astronomer

    CERN Document Server

    Sellers, David

    2012-01-01

    William Gascoigne (c.1612-44), the first inventor of the telescopic sight and micrometer—instruments crucial to the advance of astronomy—was killed in the English Civil War. His name is now known to historians of science around the world, but for some considerable time after his tragic death at the age of 32, it seemed as if his achievements would be consigned to oblivion. Most of his papers were lost in the maelstrom of war and the few that seemed to have survived later disappeared. This is the story of how his work was rescued. Woven into that story is an account of the state of astronomy and optics during Gascoigne’s lifetime, so that the reader can appreciate the significance of his discoveries.   A substantial appendix presents selected extracts from Gascoigne's correspondence. This includes much new material that has not been previously published and illustrates his efforts to explain the basis of his pioneering techniques to the satisfaction of his contemporaries.   

  19. Alterations in diffusion properties of white matter in Williams syndrome.

    Science.gov (United States)

    Arlinghaus, Lori R; Thornton-Wells, Tricia A; Dykens, Elisabeth M; Anderson, Adam W

    2011-11-01

    Diffusion tensor imaging (DTI) was used to investigate the involvement of brain white matter in Williams syndrome (WS), a genetic neurodevelopmental disorder. Whole-brain DTIs were obtained from 16 young adults with WS and 16 normal controls. A voxel-based analysis was performed to compare fractional anisotropy (FA) values between the two groups. A tract-based analysis was also performed to compare FA values between the two groups along two major white matter tracts that pass through the external capsule: the uncinate and inferior fronto-occipital fasciculi. Several regions of both increased and decreased FA were found within major white matter tracts that connect functional regions that have previously been implicated in the cognitive and neurological symptoms of the syndrome. The tract-based analysis provided additional insight into the involvement of specific white matter tracts implicated in the voxel-based analysis within the external capsule. The results from this study support previously reported changes in white matter diffusion properties in WS and demonstrate the potential usefulness for tract-based analysis in future studies of the disorder. Copyright © 2011 Elsevier Inc. All rights reserved.

  20. Addressing social skills deficits in adults with Williams syndrome.

    Science.gov (United States)

    Fisher, Marisa H; Morin, Lindsay

    2017-12-01

    Individuals with Williams syndrome (WS) are hypersocial; yet, they experience social difficulties and trouble with relationships. This report summarizes findings from three studies examining the social functioning of adults with WS and the feasibility of a social skills training program for adults with WS (SSTP-WS) through the examination of performance on initial lesson plans. Study 1: 114 parents of adults with WS completed the Social Responsiveness Scale-2. Study 2: 10 adults with WS and 12 of their parents participated in focus groups to further describe the deficits identified in Study 1 and to discuss a SSTP-WS. Study 3: 30 adults with WS were randomly assigned to 2 lessons on either conversations or relationships and pre-post change in social skills knowledge was assessed. Study 1 indicates adults with WS experience severe social impairments in social cognition, and mild-moderate impairments in social awareness and social communication. Qualitative results in Study 2 indicate a SSTP-WS should address conversation skills and relationships. In Study 3, participants showed gains in social skills knowledge following completion of lessons. A SSTP-WS may be beneficial for adults with WS. Future research should describe the social needs of individuals with WS at different ages and should further develop a SSTP-WS. Copyright © 2017 Elsevier Ltd. All rights reserved.

  1. Auditory cortical volumes and musical ability in Williams syndrome.

    Science.gov (United States)

    Martens, Marilee A; Reutens, David C; Wilson, Sarah J

    2010-07-01

    Individuals with Williams syndrome (WS) have been shown to have atypical morphology in the auditory cortex, an area associated with aspects of musicality. Some individuals with WS have demonstrated specific musical abilities, despite intellectual delays. Primary auditory cortex and planum temporale volumes were manually segmented in 25 individuals with WS and 25 control participants, and the participants also underwent testing of musical abilities. Left and right planum temporale volumes were significantly larger in the participants with WS than in controls, with no significant difference noted between groups in planum temporale asymmetry or primary auditory cortical volumes. Left planum temporale volume was significantly increased in a subgroup of the participants with WS who demonstrated specific musical strengths, as compared to the remaining WS participants, and was highly correlated with scores on a musical task. These findings suggest that differences in musical ability within WS may be in part associated with variability in the left auditory cortical region, providing further evidence of cognitive and neuroanatomical heterogeneity within this syndrome. Copyright (c) 2010 Elsevier Ltd. All rights reserved.

  2. Hydrographic trends in Prince William Sound, Alaska, 1960-2016

    Science.gov (United States)

    Campbell, Robert W.

    2018-01-01

    A five-decade time series of temperature and salinity profiles within Prince William Sound (PWS) and the immediately adjacent shelf was assembled from several archives and ongoing field programs, and augmented with archived SST observations. Observations matched with recent cool (2007-2013) and warm (2013-onward) periods in the region, and also showed an overall regional warming trend ( 0.1 to 0.2 °C decade-1) that matched long-term increases in heat transport to the surface ocean. A cooling and freshening trend ( - 0.2 °C decade-1 and 0.02 respectively) occurred in the near surface waters in some portions of PWS, particularly the northwestern margin, which is also the location of most of the ice mass in the region; discharge (estimated from other studies) has increased over time, suggesting that those patterns were due to increased meltwater inputs. Increases in salinity at depth were consistent with enhanced entrainment of deep water by estuarine circulations, and by enhanced deep water renewal caused by reductions in downwelling-favorable winds. As well as local-scale effects, temperature and salinity were positively cross correlated with large scale climate and lunar indexes at long lags (years to months), indicating the longer time scales of atmospheric and transport connections with the Gulf of Alaska. Estimates of mixed layer depths show a shoaling of the seasonal mixed layer over time by several meters, which may have implications for ecosystem productivity in the region.

  3. THE SYNTACTICAL ABILITY OF A YOUNG GIRL WITH WILLIAMS SYNDROME

    Directory of Open Access Journals (Sweden)

    Diana ARAPOVIKJ

    2008-06-01

    Full Text Available This research was carried out on a young girl with Williams syndrome, whose syntactical ability was tested longitudinally over a period of 22 months, from age 9 years and 3 months to 11 years and 1 month. The assumption was that the girl with Wil­liams syndrome would have poorer syntactical ability than children with regular development, but similar to children with specific language impair­ment (SLI and that in all tasks she would achieve better results in the final testing. Syntax was ana­lyzed on the basis of the fundamental variable of repeating sentences, which consisted of five sub-variables: literal repetition of sentences, sentences repeated with omissions, ungrammatical repetition of sentences, sentences with altered content, sen­tences not repeated. A statistical difference was found between the syntactical ability of the girl with Williams’ syndrome and children with normal development in all tested sub-variables, and her results were the same as in children with specific language impairment. Moreover, in the final test­ing the girl achieved better results than in the ini­tial test.

  4. THE HISTORY OF DESIGN EDUCATION AND WILLIAM MORRIS

    Directory of Open Access Journals (Sweden)

    Oguz DILMAC

    2015-04-01

    Full Text Available Industrial revolution had an impact on art as well as other fields of society in the years 1760-1860. The machines came to the front in together with bringing out production line to supply growing demand, and so the importance the art had diminished. The machines having some features like standard production, scales based on rules and geometric form having unnatural appearance caused the artists such as William Morris and John Ruskin to believe that the machine harmed the art. The artists such as Morris and Ruskin took a leading role in development of design idea by resisting the form of machine production devoid of art in the light of this ideas. The problem of design keeps as a current issue nowadays. That’s why, we could create a solution by having different perspectives based on previous experience and problems encountered nowadays. The problem of design keeps on up-to-date issue with the technology developing very fast today. So, this study was made with the aim to help us present right approaches towards today’s problems. This research, review of the literature obtained from architecture, history of art and industrial design on books- magazines the subject of the dissertation thesis Higher Education Center was formed with descriptive narratives. Another aim of the research carried out in this context the handmade, machine design is to examine the emerging issues in the transition to production.

  5. Signs and Stage Props in Tennessee Williams' Camino Real

    Directory of Open Access Journals (Sweden)

    Parvin Ghasemi

    2011-01-01

    Full Text Available Humans from the early times have used signs to facilitate the communication in the early societies. Semiotics is an approach wherein howness is dominant; it is the investigation of how meaning is created and communicated through systems of signs. In the dramatic texts meanings are conveyed by two different forms of language, stage direction and dialogue. Stage direction and dialogue are complementary and interdependent signifying systems. Stage directions are integral to the structure of dramatic texts and have important functions in their semantic construction. Tennessee Williams is one of the dramatists who use notes or stage directions in his plays. Through such stage devices as lighting, music and sound effects, colors, objects as symbols, transparent walls, the fluctuation of time, etc., he is after the representation of an abstract or spiritual meaning through concrete or material form. This study aims at analysis and examination of Williams’ Camino Real’s stage props and devices as signs and their relationships in the play with regard to semiotics as the theoretical framework and approach

  6. Do individuals with Williams syndrome possess absolute pitch?

    Science.gov (United States)

    Martínez-Castilla, Pastora; Sotillo, María; Campos, Ruth

    2013-01-01

    Although absolute pitch (AP) is a rare skill in typical development, individuals with Williams syndrome (WS) are often referred to as possessing this musical ability. However, there is paucity of research on the topic. In this article, 2 studies were conducted to evaluate AP in WS. In Study 1, seven musically trained individuals with WS, 14 musically trained typically developing controls matched for chronological age, and 2 experienced musicians with AP completed a pitch-identification task. Although the task was a classical assessment of AP, it required participants to have musical knowledge, and the availability and accessibility of musically trained individuals with WS is very low. In Study 2, a paradigm suitable for evaluating AP in individuals without musical training was used, which made it possible to evaluate a larger group of participants with WS. A pitch memory test for isolated tones was presented to 27 individuals with WS, 54 typically developing peers matched for chronological age, and the 2 musicians with AP. Both individuals with WS and their controls obtained low results in the two studies. They showed an arbitrary pattern of response, and their performance was far from that of musicians with AP. Therefore, participants with WS did not appear to possess AP. Unlike what is usually claimed, results suggest that AP is not a remarkable ability in WS and that, as in the typically developing population, this musical ability is also rare in individuals with WS.

  7. Lord Byron's physician: John William Polidori on somnambulism.

    Science.gov (United States)

    Finger, Stanley; Stiles, Anne

    2013-01-01

    John William Polidori (1795-1821) was the Edinburgh-trained physician hired by Lord Byron to accompany him to Switzerland, where he participated in the story-telling event proposed by Byron that led, with Polidori's help, to Mary Shelley's Frankenstein. Although those interested in English literature might also remember Polidori as the author of The Vampyre, one of the first extended works of fiction about vampires, his earlier interest in somnambulism and trance states is only beginning to be appreciated. Even more than students of Romantic literature, historians of science and medicine seem little aware of what Polidori had written about oneirodynia, a synonym for somnambulism, and how his thoughts from 1815 about such activities reflected the changing medical zeitgeist at this time. This chapter examines Polidori's medical thesis in a neuroscience context and compares what he wrote to the writings of several other physicians who were fascinated by nocturnal wanderings, their causes, their manifestations, and their possible treatments. © 2013 Elsevier B.V. All rights reserved.

  8. 'Bacilli and bullets': William Osler and the antivaccination movement.

    Science.gov (United States)

    Greenberg, S B

    2000-08-01

    Public discourse concerning current vaccination recommendations has dramatically increased. The current battle is not new, having had a lengthy foreshadowing during the 19th and early 20th centuries. Over a 30-year period, a concerted effort to limit the use of smallpox vaccine grew at the very time typhoid vaccines were being developed and advocated for widespread prevention. As a long time advocate for widespread smallpox vaccination and a supporter of the newly tested typhoid vaccine, Sir William Osler entered the public debate at the beginning of World War I. Osler was asked to address the officers and men in the British army on the need for typhoid vaccination. His speech entitled "Bacilli and Bullets" outlined the medical reasons for getting inoculated against typhoid. Osler's strong support for typhoid vaccination of the British troops was met by opposition in Parliament but not by most of the troops. Osler's arguments in support of vaccination failed to respond to the concept of "conscientious objection," which was central to the antivaccinationists' argument. Similar arguments are being propounded by current antivaccination groups.

  9. Sir William Petty: modern epidemiologist (1623-1687).

    Science.gov (United States)

    Banta, J E

    1987-01-01

    William Petty, physician, epidemiologist, political economist, demographer, cartographer, and administrator was an intellectual product of the seventeenth century. Petty was born in the year 1623 in Romsey, England of lower middle class parents; however, by the time of his death in 1687 he had become a knight of the realm, founder of the Royal Society, and friend of kings. Petty's life reflected the northern renaissance which induced such dramatic changes in science, technology, politics, and entrepreneurship. His education was eclectic, nonetheless he took his Doctor of Physic degree from Oxford in 1649 and became an Oxford don, where he spent the next few years as an academic before undertaking a definitive survey of Ireland on behalf of the Cromwell government. Ireland changed Petty's destiny and he became a man of the world and entrepreneur which stimulated his interest in public policy formulation and economics. It was Petty's peculiar genius to be innovative in the application of measurement, statistics, and mathematics to socioeconomic and demographic phenomena. As a physician he related his knowledge of health and disease to these phenomena in what in the modern context would be called human ecology or social epidemiology. These relationships and their measurement were employed to establish an objective set of data which could be analyzed for the purpose of rational public policy planning by the state. This scientific approach to public policy places Petty squarely in the context of modern epidemiologic and public health practice and marks the initiation of a major use of the epidemiologic method.

  10. Perceptual learning in Williams syndrome: looking beyond averages.

    Directory of Open Access Journals (Sweden)

    Patricia Gervan

    Full Text Available Williams Syndrome is a genetically determined neurodevelopmental disorder characterized by an uneven cognitive profile and surprisingly large neurobehavioral differences among individuals. Previous studies have already shown different forms of memory deficiencies and learning difficulties in WS. Here we studied the capacity of WS subjects to improve their performance in a basic visual task. We employed a contour integration paradigm that addresses occipital visual function, and analyzed the initial (i.e. baseline and after-learning performance of WS individuals. Instead of pooling the very inhomogeneous results of WS subjects together, we evaluated individual performance by expressing it in terms of the deviation from the average performance of the group of typically developing subjects of similar age. This approach helped us to reveal information about the possible origins of poor performance of WS subjects in contour integration. Although the majority of WS individuals showed both reduced baseline and reduced learning performance, individual analysis also revealed a dissociation between baseline and learning capacity in several WS subjects. In spite of impaired initial contour integration performance, some WS individuals presented learning capacity comparable to learning in the typically developing population, and vice versa, poor learning was also observed in subjects with high initial performance levels. These data indicate a dissociation between factors determining initial performance and perceptual learning.

  11. William Butler Yeats in the Slovene cultural space

    Directory of Open Access Journals (Sweden)

    Janez Gorenc

    2002-12-01

    Full Text Available William Butler Yeats, Irish poet, dramatist and essayist, winner of the Nobel prize in 1923, was also widely known for the active  part he played in Irish politics. Even though he was mostly involved culturally - he wro.te about Irish politics in his works, established several literary clubs, founded theatres - he also activated  himself  as a politician when he was a senator during the years 1923-1928. This article focuses on the mention of his political activities in different English and Slovene texts. It makes a presentation of the vast majority of the texts on Yeats that have appeared in Slovene. It also points out that while the majority of English encyclopaedias and literary histories openly write about Yeats's politics, Slovene texts about Yeats focus mostly on his literary opus and less on his involvement in politics. When they do mention it, however, they usually avoid the details. This article tries to determine some reasons for this fact.

  12. 20 Cataclysmic variables to be observed by William Herschel Telescope

    Science.gov (United States)

    Waagen, Elizabeth O.

    2016-05-01

    Roque Ruiz-Carmona (Ph.D. candidate, Institute of Mathematics, Astrophysics and Particle Physics, Radboud University Nijmegen, The Netherlands) has requested AAVSO assistance with his campaign to observe a set of 20 cataclysmic variables (CVs) with the William Herschel Telescope (WHT) at La Palma TONIGHT. This campaign is identical in format to the ones successfully carried out by the AAVSO on his behalf in 2015 (AAVSO Alert Notices 524 and 527). The full details of and instructions for this campaign are included here although the first of the two nights for which data are requested has passed. In order for WHT to observe each of the targets safely and to maximize the science value of the observations obtained, it is essential to know whether they are in outburst or quiescence. To this end, the PI has requested our observers to obtain one image of each target on each of TWO separate nights so he may analyze them to determine the final observing list for WHT. The images must be taken and posted within a certain window. Links to finder charts as well as reporting instructions and other information may be found in the full Alert Notice.

  13. 17 cataclysmic variables to be observed by William Herschel Telescope

    Science.gov (United States)

    Waagen, Elizabeth O.

    2015-08-01

    Roque Ruiz-Carmona (Ph.D. candidate, Institute of Mathematics, Astrophysics and Particle Physics, Radboud University Nijmegen, The Netherlands) has requested AAVSO assistance with his campaign to observe (a new set of) 17 cataclysmic variables (CVs) with the William Herschel Telescope (WHT) next week. This campaign is nearly identical in format to the one carried out by the AAVSO on his behalf in July (AAVSO Alert Notice 524). The success of that campaign prompted him to ask for the AAVSO's assistance in this new campaign. In order for WHT to observe each of the targets safely and to maximize the science value of the observations obtained, it is essential to know whether they are in outburst or quiescence. To this end, the PI has requested our observers to obtain one image of each target on each of TWO separate nights so he may analyze them to determine the final observing list for WHT. The images must be taken and posted within a certain window. Links to finder charts as well as reporting instructions and other information may be found in the full Alert Notice.

  14. French Williams syndrome's ability to produce judgments of grammaticality.

    Science.gov (United States)

    Bertho, Marie; Ehret, Margot; Schweyer, Juliette; Tyson, Nathalie; Boloh, Yves

    2014-12-01

    This article reports grammatical judgment data from eighteen French Williams syndrome (WS) (mean CA = 21.10; Mean MA = 11.2). Participants had to detect ungrammatical sentences (13 amongst a set of 26 sentences) in telling whether a given sentence was well said or not. Agrammaticality could be due to errors in tense, person agreement, gender agreement, derivational or inflectional morphology, word order and so on. As a group, WS participants scored as seven-year-olds did, far below CA-controls and MA-controls. Scores did not improve with chronological age or mental age but they were related to total IQ and verbal IQ. They showed an important variability, one similar to what was observed in four-year-olds. Although a few WS individuals had good metasyntactic abilities, these abilities generally plateau in our WS group. They were not deviant, however, as the WS's profile of difficulties across items was qualitatively very similar to the one seen in seven-year-olds. Copyright © 2014 Elsevier Ltd. All rights reserved.

  15. Percevoir Dieu ? Henri Bergson et William P. Alston

    Directory of Open Access Journals (Sweden)

    Anthony Feneuil

    2012-07-01

    Full Text Available William Alston (1921-2009 et Henri Bergson (1859-1941 semblent défendre une même thèse : celle de la valeur de l’expérience mystique pour la connaissance (valeur épistémique. L’étude comparée de la manière dont chacun d’entre eux la formule et la défend constitue un bon angle pour envisager la différence entre tradition « analytique » et tradition « continentale » en philosophie de la religion. Cet article vise à montrer les divergences et les convergences entre les deux auteurs, mais surtout à situer le point d’origine des divergences. Il apparaît que celui-ci n’est pas à chercher dans deux conceptions irréductibles de la philosophie ou de la rationalité, dans une différence de compréhension de la mystique.

  16. William Wordsworth and the ecology of authorship: the roots of environmentalism in nineteenth-century culture

    OpenAIRE

    Malla García, Noelia

    2014-01-01

    Reseña de libro: Scott Hess, William Wordsworth and the Ecology of Authorship: The Roots of Environmentalism in Nineteenth-Century Culture (Charlottesville & London: Virginia University Press, 2012), 290 pp.

  17. Läbi legendide William Shakespeare'i poole / Maris Peters

    Index Scriptorium Estoniae

    Peters, Maris

    2010-01-01

    Tutvustus: Wells, Stanley. Kas on tõsi, et Shakespeare ...? / tõlkinud Maris Peters. Tallinn : Argo, 2010. Raamat William Shakespeare kohta käivatest legendidest, kuuldustest ja teooriatest ning tema teoste autorsusest

  18. Lähtugem ehitistest! / William J. R. Curtis ; interv. Andres Kurg, Karin Hallas, Triin Ojari

    Index Scriptorium Estoniae

    Curtis, William J. R.

    1998-01-01

    24. apr. pidas Rotermanni soolalaos loengu arhitektuuriajaloolane William J. R. Curtis. Katkeid jutuajamisest W. Curtisega. Arhitektuurikriitikast, oma raamatust "Modern Architecture since 1900", millest W. Curtis praegu kriitikuna kirjutab, Lille'i projektist jm

  19. Theatre Arts' Michael Anthony Williams appears in Jodie Foster's new film, The Brave One

    OpenAIRE

    Adams, Louise

    2007-01-01

    Virginia Tech Theatre Arts Visiting Instructor Michael Anthony Williams is in the cast of Jodie Foster's new movie, The Brave One, being released to theatres around the nation on Friday, Sept. 14, by Warner Brothers Studios.

  20. Prince William Sound, Alaska ESI: ESI (Environmental Sensitivity Index Shoreline Types)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set comprises the Environmental Sensitivity Index (ESI) data for Prince William Sound, Alaska. ESI data characterize estuarine environments and wildlife by...

  1. Prince William Sound, Alaska ESI: M_MAMMAL (Marine Mammal Polygons)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set comprises the Environmental Sensitivity Index (ESI) data for Prince William Sound, Alaska. ESI data characterize estuarine environments and wildlife by...

  2. Anaesthetic genetics and genomics | Welch | Southern African ...

    African Journals Online (AJOL)

    Some common genetically determined anaesthetic conditions, such as malignant hyperthermia, “scoline apnoea”, “halothane hepatitis” and porphyria, are fairly well described, and the genetic differences in enzyme, receptor and ion channel systems are slowly being elucidated. These genomic differences allow some ...

  3. Application of Choi—Williams Reduced Interference Time Frequency Distribution to Machinery Diagnostics

    Directory of Open Access Journals (Sweden)

    Howard A. Gaberson

    1995-01-01

    Full Text Available This article discusses time frequency analysis of machinery diagnostic vibration signals. The short time Fourier transform, the Wigner, and the Choi–Williams distributions are explained and illustrated with test cases. Examples of Choi—Williams analyses of machinery vibration signals are presented. The analyses detect discontinuities in the signals and their timing, amplitude and frequency modulation, and the presence of different components in a vibration signal.

  4. Hemizygosity at the elastin locus and clinical features of Williams syndrome

    Energy Technology Data Exchange (ETDEWEB)

    Morimoto, Y; Kuwano, A. [Ehime Univ. School of Medicine (Japan); Kuwajima, K. [Ibaraki Perfectural Handicap Children`s Hopsital (Japan)] [and others

    1994-09-01

    Williams syndrome is a recognizable syndrome characterized by distinctive facial appearance, gregarious personality, mental retardation, congenital heart defect, particularly supravalvular aortic stenosis (SVAS), and joint limitation. SVAS is an autosomal vascular disorder and the elastin gene was disrupted in patients with SVAS. Ewat et al. reported that hemizygosity at the elastin locus was detected in four familial and five sporadic cases of Williams syndrome. However, three patients did not have SVAS. We reconfirmed hemizygosity at the elastin locus in five patients with typical clinical features of Williams syndrome. Hemizygosity was detected in four cases with SVAS. However, one patient with distinctive facial appearance and typical Williams syndrome personality had two alleles of the elastin gene, but he did not have the congenital heart anomaly. Williams syndrome is thought to be a contiguous gene disorder. Thus, our data suggest that the elastin gene is responsible for the vascular defect in patients with Williams syndrome, and flanking genes are responsible for characteristic facial appearance and personality.

  5. The rhetorical strategy of William Paley's Natural theology (1802): part 1, William Paley's Natural theology in context.

    Science.gov (United States)

    O'Flaherty, Niall

    2010-03-01

    This article reconstructs the historical and philosophical contexts of William Paley's Natural theology (1802). In the wake of the French Revolution, widely believed to be the embodiment of an atheistic political credo, the refutation of the transmutational biological theories of Buffon and Erasmus Darwin was naturally high on Paley's agenda. But he was also responding to challenges arising from his own moral philosophy, principally the psychological quandary of how men were to be kept in mind of the Creator. It is argued here that Natural theology was the culmination of a complex rhetorical scheme for instilling religious impressions that would increase both the virtue and happiness of mankind. Philosophy formed an integral part of this strategy, but it did not comprise the whole of it. Equally vital were those purely rhetorical aspects of the discourse which, according to Paley, were more concerned with creating 'impression'. This facet of his writing is explored in part one of this two-part article. Turning to the argumentative side of the scheme, part two examines Paley's responses to David Hume and Erasmus Darwin in the light of the wider strategy of inculcation at work throughout all his writings.

  6. Ribosomal accretion, apriorism and the phylogenetic method: A response to Petrov and Williams

    Directory of Open Access Journals (Sweden)

    Derek eCaetano-Anollés

    2015-06-01

    Full Text Available Historical (ideographic and non-historical (nomothetic studies of ribosomal accretion appear to arrive at diametrically opposite conclusions. Phylogenetic analysis of thousands of RNA molecules and protein structures in hundreds of genomes supports the structural origin of the ribosome in RNA decoding and ribosomal mechanics. Predictions from extant features in a handful of rRNA structural models of the large ribosomal subunit support its origin in protein biosynthesis. In recent correspondence, one of us reported that correcting dismissals of conflicting data and avoiding unwarranted assumptions of the nomethetic method reconciled conclusions. In response, Petrov and Williams dismissed our arguments claiming we did not understand their ‘BS’ algorithmic model of ribosomal apical growth. Instead, they controverted the historical approach. Here we show that their objections to the phylogenetic method are unjustified, that the BS algorithm subjectively guarantees back-in-time molecular deconstructions towards the protein biosynthetic core, and that processes of ribosomal growth are much more complex. We prompt abandoning apriorism, decreasing ad hoc hypotheses and integrating historical and non-historical scientific methods.

  7. Pragmatic Abilities of Children with Williams Syndrome: A Longitudinal Examination

    Science.gov (United States)

    John, Angela E.; Dobson, Lauren A.; Thomas, Lauren E.; Mervis, Carolyn B.

    2012-01-01

    Prior research has indicated that pragmatics is an area of particular weakness for individuals with Williams syndrome (WS). To further address this aspect of the WS social phenotype, we used an individual differences approach to consider both cross-sectional and longitudinal relations among different pragmatic abilities for 14 children with WS, taking into account individual differences in non-verbal reasoning abilities. We also considered the relations between pragmatic abilities and expressive vocabulary ability. Participants were tested at two time points: as 4-year-olds during a 30-min play session with their mothers (Time 1) and an average of 5.87 years later during a one-on-one conversation with a familiar researcher (Time 2). Children’s intellectual and expressive vocabulary abilities were assessed at both time points. Results indicated that the ability to verbally contribute information beyond what was required in response to a question (ExtendQ) was significantly related to the ability to verbally contribute new information in the absence of a question (ExtendS) both at age 4 years and during primary school. At age 4, both the ability to pair verbalizations with eye contact in triadic interactions (secondary intersubjectivity) and expressive vocabulary ability were related to both ExtendQ and ExtendS. Finally, both ExtendQ and the ability to pair verbalizations with eye contact (intersubjectivity) at age 4 years predicted ExtendQ at age 9–12 years. The theoretical implications of our findings and the importance of early pragmatic language intervention for children who have WS are discussed. PMID:22719734

  8. Pragmatic Abilities of Children with Williams Syndrome: A Longitudinal Examination

    Directory of Open Access Journals (Sweden)

    Angela E. John

    2012-06-01

    Full Text Available Although prior research has indicated that pragmatics is an area of particular weakness for individuals with Williams syndrome (WS, the relations among different pragmatic abilities and the relations between pragmatic ability and expressive vocabulary ability have yet to be addressed. In addition, analyses of the relations between the same type of pragmatic ability over time have not been reported. The present study was designed to address these questions. We considered the pragmatic language abilities of 14 children with WS at two time points: as 4-year-olds during a 30-minute play-session with their mothers (Time 1 and an average of 5.87 years later during a one-on-one conversation with a familiar researcher (Time 2. Children’s intellectual and expressive vocabulary abilities were assessed at both time points. Results indicated that the ability to verbally contribute information beyond what was required in response to a question was significantly related to the ability to verbally contribute new information in the absence of a question both at age 4 years and during primary school. At age 4, both the ability to pair verbalizations with eye contact (intersubjectivity and expressive vocabulary ability were related to the ability to verbally contribute information beyond what was expected within a social interaction. Finally, the ability to verbally contribute new information to a social interaction beyond what was required to answer a question and the ability to pair verbalizations with eye contact (intersubjectivity at age 4 years predicted the ability to verbally contribute new information beyond what was required to answer a question at age 9 – 12 years. The theoretical implications of our findings and the importance of early pragmatic language intervention for children who have WS are discussed.

  9. 21 Cataclysmic variables to be observed by William Herschel Telescope

    Science.gov (United States)

    Waagen, Elizabeth O.

    2016-12-01

    Roque Ruiz-Carmona (Ph.D. candidate, Institute of Mathematics, Astrophysics and Particle Physics, Radboud University Nijmegen, The Netherlands) has requested AAVSO assistance with his campaign to observe a set of 21 cataclysmic variables (CVs) with the William Herschel Telescope (WHT) at La Palma on 2016 December 16. This campaign is essentially identical in format to the ones successfully carried out by the AAVSO on his behalf in 2015 and in May 2016 (AAVSO Alert Notices 524, 527, 543). Ruiz-Carmona writes: "As the end of my PhD is closer now, this is the second-to-last campaign monitoring CVs into outburst. As an update on my research, it seems that unexpectedly spiral density waves can only be detectable in high inclination systems and it seems that the luminosity of the disk in outburst outshines the spiral pattern for the rest of the system. This can also have deep implications: it can be that the spiral density waves are only an effect of the atmospheres of the disks and are therefore unrelated to transport of matter and angular momentum in the disks. In order to investigate this hypothesis, the sample of CVs I would like to monitor contains only eclipsing systems."[As before,] I just need to know if the targets are in outburst or not..." The PI has requested AAVSO observers to obtain one image of each target on each of TWO separate nights so he may analyze them to determine the final observing list for WHT. Links to finder charts as well as reporting instructions and other information may be found in the full Alert Notice.

  10. Utility of the Hebb–Williams Maze Paradigm for Translational Research in Fragile X Syndrome: A Direct Comparison of Mice and Humans

    Science.gov (United States)

    Boutet, Isabelle; Collin, Charles A.; MacLeod, Lindsey S.; Messier, Claude; Holahan, Matthew R.; Berry-Kravis, Elizabeth; Gandhi, Reno M.; Kogan, Cary S.

    2018-01-01

    To generate meaningful information, translational research must employ paradigms that allow extrapolation from animal models to humans. However, few studies have evaluated translational paradigms on the basis of defined validation criteria. We outline three criteria for validating translational paradigms. We then evaluate the Hebb–Williams maze paradigm (Hebb and Williams, 1946; Rabinovitch and Rosvold, 1951) on the basis of these criteria using Fragile X syndrome (FXS) as model disease. We focused on this paradigm because it allows direct comparison of humans and animals on tasks that are behaviorally equivalent (criterion #1) and because it measures spatial information processing, a cognitive domain for which FXS individuals and mice show impairments as compared to controls (criterion #2). We directly compared the performance of affected humans and mice across different experimental conditions and measures of behavior to identify which conditions produce comparable patterns of results in both species. Species differences were negligible for Mazes 2, 4, and 5 irrespective of the presence of visual cues, suggesting that these mazes could be used to measure spatial learning in both species. With regards to performance on the first trial, which reflects visuo-spatial problem solving, Mazes 5 and 9 without visual cues produced the most consistent results. We conclude that the Hebb–Williams mazes paradigm has the potential to be utilized in translational research to measure comparable cognitive functions in FXS humans and animals (criterion #3). PMID:29643767

  11. WEAVE: the next generation wide-field spectroscopy facility for the William Herschel Telescope : The next generation wide-field spectroscopy facility for the William Herschel Telescope

    NARCIS (Netherlands)

    Dalton, Gavin; Trager, Scott C.; Abrams, Don Carlos; Carter, David; Bonifacio, Piercarlo; Aguerri, J. Alfonso L.; MacIntosh, Mike; Evans, Chris; Lewis, Ian; Navarro, Ramon; Agocs, Tibor; Dee, Kevin; Rousset, Sophie; Tosh, Ian; Middleton, Kevin; Pragt, Johannes; Terrett, David; Brock, Matthew; Benn, Chris; Verheijen, Marc; Cano Infantes, Diego; Bevil, Craige; Steele, Iain; Mottram, Chris; Bates, Stuart; Gribbin, Francis J.; Rey, Jürg; Rodriguez, Luis Fernando; Delgado, Jose Miguel; Guinouard, Isabelle; Walton, Nic; Irwin, Michael J.; Jagourel, Pascal; Stuik, Remko; Gerlofsma, Gerrit; Roelfsma, Ronald; Skillen, Ian; Ridings, Andy; Balcells, Marc; Daban, Jean-Baptiste; Gouvret, Carole; Venema, Lars; Girard, Paul

    We present the preliminary design of the WEAVE next generation spectroscopy facility for the William Herschel Telescope (WHT), principally targeting optical ground-based follow up of upcoming ground-based (LOFAR) and spacebased (Gaia) surveys. WEAVE is a multi-object and multi-IFU facility utilizing

  12. Tracing sediment sources in the Williams River catchment using caesium-137 and heavy metals: towards an assessment of the relative importance of surface erosion and gully erosion

    International Nuclear Information System (INIS)

    Krause, A.K.; Kalma, J.D.; Loughran, R.J.

    1999-01-01

    Recent sediment sourcing in the 1175km 2 Williams River catchment near Newcastle, NSW, has involved the use of caesium-137 ( 137 Cs) and heavy metals to identify zones of erosion and estimate erosion rates. Sediment sources to the Williams River include sheet erosion from forested and grazed lands, stream channels (especially banks), gullies and roads. The fallout environmental radioisotope 137 Cs was used to assess the erosion status of five vegetated slopes using soil sampling along transects. The net loss or gain of 137 Cs at each sampling point was compared with the 137 Cs level at a reference site at the slope crest. Net soil loss at each point was calculated from an Australian regression model relating net soil loss from runoff-erosion plots to 137 Cs deficit in soils (n=34; r=0.84). Net soil gain was calculated using the regression model in reverse mode. A weighted net soil loss (or gain) was then calculated for each slope transect. Results showed low net soil loss, ranging from zero to 0.64 t ha -1 yr 1 , suggesting that slopes were not major contributors of sediment to the Williams River. A small sub-catchment south of Wirragulla Hill, typical of the lower Williams region, was selected for more detailed tracing of sediment sources. The catchment contains gullies, sheet-erosion exposed sub-soil, grassland and one unsealed road. Heavy metals and 137 Cs have been used to fingerprint the sources, and these measurements will be compared with suspended sediment collected from drainage water in the creek. Only preliminary results have been obtained for this component of the study. The paper will assess these two approaches for the identification of sediment sources and discuss practical applications in water resources management

  13. Observations from the Williams Tower measurement site during TexAQS 2000: an Overview

    Science.gov (United States)

    Imre, D.; Brechtel, F.; Zelenyuk, A.; Doskey, P.; Spicer, C.; Joseph, D.; Berkowitz, C.; Alexander, M.; Cowin, J.; Weinstein-Lloyd, J.; Baumann, K.

    2002-12-01

    The Williams Tower measurement site operated during TexAQS 2000 provided a unique sampling opportunity making it possible to study the meteorological and chemical day-night evolution of the planetary boundary layer. The skyscraper measurements were made from the 62nd floor of Williams Tower located in uptown Houston. Teams of scientists from six organizations set up 20 instruments for sampling 24 hours a day, seven days a week. Participant groups included Battelle's Columbus Operations, Pacific Northwest National Laboratory, Brookhaven National Laboratory, Argonne National Laboratory, State University of New York at Old Westbury, Georgia Institute of Technology, University of California at Davis, and the Texas Natural Resources Conservation Commission. The measurement systems filled two rooms; one room was used primarily for gas-phase measurements of O3, NO/NOy, PAN, SO2, CO, CH2O, HNO3, HONO, H2O2, and organic peroxide. Temperature, pressure and moisture were also monitored. The measurements in the 2nd room focused on aerosol characterization some of which used new techniques. Aerosol size distribution was obtained using two scanning differential mobility analyzers. Aerosol bulk composition was obtained using time resolved filter sampling. Single particle size and composition was measured using a sampler that provides atomic composition using scanning electron microscopy with energy-dispersed X-ray analysis, and real-time single particle time of flight mass spectrometer. This paper will present the overview of the tower observations made at the height of 830 feet above the ground in the context of results from aircraft and other surface site observations. The data provide a rather complete suite of gas and aerosol measurements which makes it possible to characterize the Houston air west of the major emission sources. The elevated measurement site also makes it possible to investigate the chemistry within and above the nocturnal boundary layer. Results from box

  14. The natural petroleum hydrocarbon background in subtidal sediments of Prince William Sound, Alaska

    International Nuclear Information System (INIS)

    Page, D.S.; Boehm, P.D.; Douglas, G.S.; Bence, A.E.

    1993-01-01

    A natural regional petroleum hydrocarbon background has been identified in the subtidal sediments of Prince William Sound. This hydrocarbon background, which is readily distinguished from Exxon Valdez spill oil by advanced hydrocarbon fingerprinting methods, is derived from petroleum seeps in the eastern Gulf of Alaska. The Alaska Coastal Current carries fine-grained sediments and associated hydrocarbons into the Sound where they are deposited. This activity has been ongoing for the past 160 years and probably for many thousands of years. Results of a stratified random study (SRS) of nearshore subtidal sediments conducted in 1990 and a fixed site study conducted in 1989, 1990, and 1991 show that this background is significant even in shallow water (3--30 m) and that it is a general phenomenon of the Sound. Polycyclic aromatic hydrocarbon (PAH) mixing model calculations show that, where present in nearshore subtidal sediments, residues of Exxon Valdez spill oil form a small increment on the natural background. The recognition of pre-existing natural and anthropogenic hydrocarbon backgrounds in a spill area is a fundamentally important component of natural resource damage assessment

  15. Leftward lateralization of auditory cortex underlies holistic sound perception in Williams syndrome.

    Science.gov (United States)

    Wengenroth, Martina; Blatow, Maria; Bendszus, Martin; Schneider, Peter

    2010-08-23

    Individuals with the rare genetic disorder Williams-Beuren syndrome (WS) are known for their characteristic auditory phenotype including strong affinity to music and sounds. In this work we attempted to pinpoint a neural substrate for the characteristic musicality in WS individuals by studying the structure-function relationship of their auditory cortex. Since WS subjects had only minor musical training due to psychomotor constraints we hypothesized that any changes compared to the control group would reflect the contribution of genetic factors to auditory processing and musicality. Using psychoacoustics, magnetoencephalography and magnetic resonance imaging, we show that WS individuals exhibit extreme and almost exclusive holistic sound perception, which stands in marked contrast to the even distribution of this trait in the general population. Functionally, this was reflected by increased amplitudes of left auditory evoked fields. On the structural level, volume of the left auditory cortex was 2.2-fold increased in WS subjects as compared to control subjects. Equivalent volumes of the auditory cortex have been previously reported for professional musicians. There has been an ongoing debate in the neuroscience community as to whether increased gray matter of the auditory cortex in musicians is attributable to the amount of training or innate disposition. In this study musical education of WS subjects was negligible and control subjects were carefully matched for this parameter. Therefore our results not only unravel the neural substrate for this particular auditory phenotype, but in addition propose WS as a unique genetic model for training-independent auditory system properties.

  16. Thinking inside the box: Spatial frames of reference for drawing in Williams syndrome and typical development.

    Science.gov (United States)

    Hudson, Kerry D; Farran, Emily K

    2017-09-01

    Successfully completing a drawing relies on the ability to accurately impose and manipulate spatial frames of reference for the object that is being drawn and for the drawing space. Typically developing (TD) children use cues such as the page boundary as a frame of reference to guide the orientation of drawn lines. Individuals with Williams syndrome (WS) typically produce incohesive drawings; this is proposed to reflect a local processing bias. Across two studies, we provide the first investigation of the effect of using a frame of reference when drawing simple lines and shapes in WS and TD groups (matched for non-verbal ability). Individuals with WS (N=17 Experiment 1; N=18 Experiment 2) and TD children matched by non-verbal ability drew single lines (Experiment One) and whole shapes (Experiment Two) within a neutral, incongruent or congruent frame. The angular deviation of the drawn line/shape, relative to the model line/shape, was measured. Both groups were sensitive to spatial frames of reference when drawing single lines and whole shapes, imposed by a frame around the drawing space. A local processing bias in WS cannot explain poor drawing performance in WS. Crown Copyright © 2017. Published by Elsevier Ltd. All rights reserved.

  17. The Drosophila agnostic Locus: Involvement in the Formation of Cognitive Defects in Williams Syndrome.

    Science.gov (United States)

    Nikitina, E A; Medvedeva, A V; Zakharov, G A; Savvateeva-Popova, E V

    2014-04-01

    The molecular basis of the pathological processes that lead to genome disorders is similar both in invertebrates and mammals. Since cognitive impairments in Williams syndrome are caused by LIMK1 hemizygosity, could the spontaneous and mutant variants of the Drosophila limk1 gene serve as a model for studying two diagnostic features from three distinct cognitive defects of the syndrome? These two symptoms are the disturbance of visuospatial orientation and an unusualy strong fixation on the faces of other people during pairwise interaction with a stranger. An experimental approach to the first cognitive manifestation might be an analysis of the locomotor behavior of Drosophila larvae involving visuospatial orientation during the exploration of the surrounding environment. An approach to tackle the second manifestation might be an analysis of the most natural ways of contact between a male and a female during courtship (the first stage of this ritual is the orientation of a male towards a female and following the female with constant fixation on the female's image). The present study of locomotor activity and cognitive repertoire in spontaneous and mutant variants of the Drosophila agnostic locus allows one to bridge alterations in the structure of the limk1 gene and behavior.

  18. Williams Expansion Terms and their Importance for Accurate Stress Field Description in Specimens with a Crack

    Directory of Open Access Journals (Sweden)

    Lucie MALÍKOVÁ

    2013-12-01

    Full Text Available The paper deals with an analysis of the stress and displacement fields in various cracked specimens (loaded in mode I as well as in mode II. The main goal is to determine an accurate approximation of the near-crack-tip fields which can be subsequently used e.g. in the case of quasi-brittle materials for estimation of the extent of a nonlinear zone at the crack tip in general, the fracture process zone in particular. Values of coefficients of the so-called higher-order terms of the power expansion by which the fields can be expressed are determined via regression from results of numerical simulations. The analysis is conducted using 2D numerical models and ANSYS FE computational system is employed. Various aspects regarding the description of the stress/displacement fields by means of the Williams expansion are discussed; especially the convergence of the coefficients of the first several terms of the series expansion, their absolute values and importance for an accurate stress approximation.

  19. William D. Harper, Jr, MS, DC: Anything Can Cause Anything

    Science.gov (United States)

    Keating, Joseph C.

    2008-01-01

    Trained as an engineer and a chiropractor, William D. Harper, Jr. made his career in the healing arts as instructor, writer and president of the Texas Chiropractic College (TCC). A native of Texas who grew up in various locales in the Lone Star State, in Mexico and in the Boston area, he took his bachelor’s and master’s degree in engineering in 1933 and 1934 from the Massachusetts Institute of Technology, and his chiropractic degree at TCC in 1942. Dissatisfied with the “foot-on-the-hose” concept of subluxation syndrome (D.D. Palmer’s second theory), Dr. Harper studied and wrote about aberrant neural irritation as an alternative explanation for disease and for the broad clinical value he perceived in the chiropractic art. In this he paralleled much of D.D. Palmer’s third theory of chiropractic. His often reprinted textbook, Anything Can Cause Anything, brought together much of what he had lectured and written about in numerous published articles. He was well prepared for the defense of chiropractic that he offered in 1965 in the trial of the England case in federal district court in Louisiana. The case was lost when the court ruled that the legislature rather than the judiciary should decide whether to permit chiropractors to practice, but Harper’s performance was considered excellent. He went on to guide the TCC as president from 1965 through 1976, its first 11 years after relocating from San Antonio to Pasadena, Texas. Harper built the school – its faculty, staff and facilities – from very meager beginnings to a small but financially viable institution when he departed. Along the way he found fault with both chiropractic political camps that vied for federal recognition as the accrediting agency for chiropractic colleges in the United States. Dr. Bill Harper was a maverick determined to do things his way, and in many respects he was successful. He left a mark on the profession that merits critical analysis. PMID:18327301

  20. Approach to downstream planning for nearshore response and sensitive areas protection outside Prince William Sound, Alaska

    International Nuclear Information System (INIS)

    DeCola, E.G.; Robertson, T.L.; Robertson, R.; Banta, J.

    2004-01-01

    This study assessed the need for an oil spill response plan for downstream coastal communities that could be affected by oil spilled from tankers travelling in Prince William Sound, Alaska. For the purpose of oil spill contingency planning, the State of Alaska has been divided into the Kodiak and Cook Inlet sub-areas that are at risk for downstream impacts from a Prince William Sound oil spill. The 1989 Exxon Valdez oil spill provided an example of a worst-case scenario oil spill from a tanker in Prince William Sound, but the oil spill planning system that has evolved in Alaska does not adequately plan for on oil spill that originates in one sub-area of the state, but impacts other sub-areas in the downstream spill path. This study analyzed the gaps that exist in the current response planning system in the Prince William Sound, Cook Inlet and Kodiak sub-areas. A method was proposed to improve the existing response plans so that emergency response teams are better prepared to manage cross-boundary oil spills originating in Prince William Sound. The proposed method focuses on nearshore response and sensitive areas protection for coastlines and communities that are at risk for oil spills from a tanker travelling the Trans-Alaska Pipeline System (TAPS). 11 refs., 3 figs

  1. Conceptualizing neurodevelopmental disorders through a mechanistic understanding of fragile X syndrome and Williams syndrome.

    Science.gov (United States)

    Fung, Lawrence K; Quintin, Eve-Marie; Haas, Brian W; Reiss, Allan L

    2012-04-01

    The overarching goal of this review is to compare and contrast the cognitive-behavioral features of fragile X syndrome (FraX) and Williams syndrome and to review the putative neural and molecular underpinnings of these features. Information is presented in a framework that provides guiding principles for conceptualizing gene-brain-behavior associations in neurodevelopmental disorders. Abnormalities, in particular cognitive-behavioral domains with similarities in underlying neurodevelopmental correlates, occur in both FraX and Williams syndrome including aberrant frontostriatal pathways leading to executive function deficits, and magnocellular/dorsal visual stream, superior parietal lobe, inferior parietal lobe, and postcentral gyrus abnormalities contributing to deficits in visuospatial function. Compelling cognitive-behavioral and neurodevelopmental contrasts also exist in these two disorders, for example, aberrant amygdala and fusiform cortex structure and function occurring in the context of contrasting social behavioral phenotypes, and temporal cortical and cerebellar abnormalities potentially underlying differences in language function. Abnormal dendritic development is a shared neurodevelopmental morphologic feature between FraX and Williams syndrome. Commonalities in molecular machinery and processes across FraX and Williams syndrome occur as well - microRNAs involved in translational regulation of major synaptic proteins; scaffolding proteins in excitatory synapses; and proteins involved in axonal development. Although the genetic variations leading to FraX and Williams syndrome are different, important similarities and contrasts in the phenotype, neurocircuitry, molecular machinery, and cellular processes in these two disorders allow for a unique approach to conceptualizing gene-brain-behavior links occurring in neurodevelopmental disorders.

  2. Three-dimensional transport theory: Evaluation of analytical expressions of Williams and verification of MCNP

    International Nuclear Information System (INIS)

    Jeong, Jeho; White, Nathan E.; Loyalka, Sudarshan K.

    2015-01-01

    Highlights: • An evaluation of 3-D neutron transport analytical expressions of Williams. • Techniques for oscillating, singular and infinite integrals are applied. • Disagreements with reported values are rare even at 5 significant figures. • MCNP is verified against analytical results for several benchmarks. • MCNP results generally agree with analytical results, except near singularities. - Abstract: “Three-dimensional transport theory: an analytical solution of an internal beam searchlight problem, I”, Annals of Nuclear Energy, 36(8), 1256–1261 (2009) by Williams extends the range of analytical solutions, and the associated development of techniques, numerical results and analysis near singularities. The final integrals are not easy to evaluate as the integrands are highly oscillatory, singular and also on infinite range. We report here some further numerical evaluations of expressions of Williams, and also compare these with those of Williams and Ganapol and Kornreich. The numerical results compare very well. The disagreements are very rare, and even then in the fifth decimal place. We are also able to explore the nature of the results near singularities in conformity with the results of Williams. We also verify MCNP-5, the widely used Monte Carlo code against these analytical results. We have found that MCNP is easily able to provide results within 0.1% deviation from the “exact” results for most cases, and within 1% for almost all cases. It is challenged near the singularities, however, where the deviations are larger.

  3. Models for a zero-yield energy rise and their economic implications. Pt. 2. Effects of energy taxation and compensation; Modelle einer aufkommensneutralen Energiepreiserhoehung und ihre wirtschaftlichen Auswirkungen. T. 2. Auswirkungen der Energiebesteuerung und Kompensation

    Energy Technology Data Exchange (ETDEWEB)

    Kohlhaas, M. [Deutsches Inst. fuer Wirtschaftsforschung (DIW), Berlin (Germany); Welsch, H. [Deutsches Inst. fuer Wirtschaftsforschung (DIW), Berlin (Germany)

    1995-06-01

    The authors present and compare various models on the effects of energy price rises through taxation. Such taxes could be introduced within the framework of energy and climate protection policies. (UA) [Deutsch] Es werden mehrere Modelle vorgestellt und verglichen, welche die wirtschaftlichen Auswirkungen von Energiepreiserhoehungen durch Steuern untersuchen, die im Rahmen einer Energie- und Klimaschutzpolitik eingefuehrt werden koennten. (UA)

  4. Obituary: William F. M. Buscombe, 1918-2003

    Science.gov (United States)

    Taam, Ronald Everett; Bahng, John D. R.

    2003-12-01

    William Buscombe, an emeritus professor at Northwestern University, died from a massive stroke on 13 March 2003. He was a stellar spectroscopist and was working on the 16th edition of his catalog, entitled ``MK Spectral Classifications" at the time of his death. Bill was born on 12 February 1918 in Hamilton, Canada to Ethel Minett Buscombe and William Henry Buscombe. His mother was a business woman prior to marriage and his father was an executive secretary to a fire insurance company. His interest in astronomy was stimulated by a mathematics teacher in grade school and this interest carried over to his undergraduate years at the University of Toronto where he worked as a research assistant measuring stellar spectra at the David Dunlop Observatory. He earned a BA degree in Mathematics and Physics in 1940. Upon graduation he entered the graduate program in meteorology under the Department of Transport of the Government of Canada and worked as a meteorologist for the Canadian government until 1945. His studies and service eventually led to a MA degree in Meteorology from the University of Toronto in 1948. From the period 1945 to 1948, Bill was an instructor in the Department of Mathematics at the University of Saskatchewan. During the summer of 1947 Bill resumed his research in astronomy working with Andew McKellar in a study of the intensities of molecular bands in R-type stars at the Dominion Astrophysical Observatory. Subsequently, Bill entered into the graduate program in the Department of Astronomy at Princeton University where he worked with Martin Schwarzschild and Lyman Spitzer, Jr. In 1950, he was awarded a PhD in Astronomy for his thesis entitled, ``Spectrophotometry of Early A-Type Stars." Bill joined the staff at the Mt. Wilson and Palomar Observatories as a Fellow of the Carnegie Institution of Washington from 1950--1952. During this period he spent a significant amount of time observing at Mount Wilson studying the variations of atomic absorption lines

  5. A case of William's syndrome associated peripheral pulmonary arterial stenosis

    Energy Technology Data Exchange (ETDEWEB)

    Jung, Kyung Hwa; Hwang, Mi Soo; Kim, Sun Yong; Chang, Jae Chun; Park, Bok Hwan [College of Medicine, Yeungam University, Daegu (Korea, Republic of)

    1988-06-15

    William's syndrome, in order to more completely delineate the total spectrum of the disorder, indicates that 'infantile hypercalcemia', 'peculiar facies' and 'supravalvular aortic stenosis.' In has other many vascular anomalies, such as peripheral pulmonary arterial stenosis, coronary arterial stenosis, celiac arterial stenosis, and renal aterial stenosis. Only 32% of the patients have evidence of supravalvular aortic stenosis. And it is very rare disease entity that has been reported rarely in Korea. Recently authors experienced a case that was questioned William's syndrome with peripheral pulmonary arterial stenosis, clinically and preliminary radiologically and this case was confirmed by operation. Here we report a case of William's syndrome with peripheral pulmonary arterial stenosis and reviewed literatures.

  6. The Williams-Weizsaecker method and similar approximation methods in quantum electrodynamics

    International Nuclear Information System (INIS)

    Kessler, P.

    1975-01-01

    The Williams-Weizsacker method (nowadays also called 'equivalent photon method'), its history, its various formulations and its many applications in high-energy physics are described. Three different proofs are given of the Williams- Weizsacker approximation formula; one is based on classical electromagnetism, the second one on standard Feynman diagram calculation in quantum electrodynamics, and the third one on a generalized (invariant) helicity method. Several applications are discussed in detail, in particular: i) Nuclear interactions of underground cosmic ray muons; ii) inelastic scattering of high-energy particles, in accelerators, through the electromagnetic field of nuclear targets; iii) photon-photon collisions in electron-positron storage rings. The method of quasi real processes, an extension of the Williams-Weizsacker method to processes where various virtual particles other than photons (in particular, electrons) are exchanged, is also described, and some of its applications are shown. (Auth.)

  7. Revolution and Exploration: the English Translations of Rousseau and Humboldt by Helen Maria Williams

    Directory of Open Access Journals (Sweden)

    Paula Yurss Lasanta

    2017-12-01

    Full Text Available British author Helen Maria Williams (1759-1827 was a well-known figure in the eighteenth century literary circles, whose work was praised by Elizabeth Montagu, Samuel Johnson, Dorothy and William Wordsworth, Mary Wollstonecraft, Hester Piozzi or Alexander von Humboldt.  In her early poems  Edwin and Eltruda (1782, An Ode to the Peace (1783 and Peru (1784, Williams starts to reveal her political tendencies by appealing to strong empathic feelings as a key to social and political transformation. As a result of her interest in politics, she travelled to France in 1790 and published her most acclaimed work Letters from France (1790. However, the rest of her production has received little critical attention by modern scholars, who have overlooked her involvement in translation. Williams’ only extant novel, Julia (1790 is in fact a creative translation of Rousseau’s Julie ou La Nouvelle Héloïse (1761, in which Williams includes poems that evidence her interest in revolutionary politics. Four years later, she translated Bernardin de Saint Pierre’s Paul et Virginie, while she was imprisoned in Paris. While translating novels was regarded as a respectable exercise for women writers, Williams challenges gender assumptions by translating Researches (1814 and the seven volumes of Personal Narrative (1814-1829, which had been produced by one of the most influential eighteenth century scientists, Alexander von Humboldt. This article interrogates how Williams makes use of translation to access areas of knowledge traditionally restricted to men, such as philosophy, politics and science. For this purpose, I will focus on her translations of the work of two leading intellectual figures of the eighteenth century,  Rousseau and Von Humboldt.

  8. Infrared astronomy seeing the heat : from William Herschel to the Herschel space observatory

    CERN Document Server

    Clements, David L

    2014-01-01

    Uncover the Secrets of the Universe Hidden at Wavelengths beyond Our Optical GazeWilliam Herschel's discovery of infrared light in 1800 led to the development of astronomy at wavelengths other than the optical. Infrared Astronomy - Seeing the Heat: from William Herschel to the Herschel Space Observatory explores the work in astronomy that relies on observations in the infrared. Author David L. Clements, a distinguished academic and science fiction writer, delves into how the universe works, from the planets in our own Solar System to the universe as a whole. The book first presents the major t

  9. The gluon propagator in non-Abelian Weizsaecker-Williams fields

    International Nuclear Information System (INIS)

    Ayala, A.; Jalilian-Marian, J.; McLerran, L.; Venugopalan, R.

    1995-01-01

    The authors carefully compute the gluon propagator in the background of a non-Abelian Weizsaecker-Williams field. This background field is generated by the valence quarks in very large nuclei. They find contact terms in the small fluctuation equations of motion which induce corrections to a previously incorrect result for the gluon propagator in such a background field. The well known problem of the Hermiticity of certain operators in Light Cone gauge is resolved for the Weizsaecker-Williams background field. This is achieved by working in a gauge where singular terms in the equations of motion are absent and then gauge transforming the small fluctuation fields to Light Cone gauge

  10. The Reverend Dr William Henry Dallinger, F.R.S. (1839-1909).

    Science.gov (United States)

    Haas, J W

    2000-01-01

    William Dallinger illustrates a social outsider concerned with the application of science to the physical, intellectual and spiritual health of his homeland, who forced his way into the scientific life of his nation. His path was encouraged by mentors such as William McKenny who steered him into the Methodist ministry, James Drysdale who helped him get established as a scientist and John Tyndall, Thomas Huxley and Charles Darwin who encouraged his scientific efforts and smoothed his way into his nation's highest scientific circles. The shadowy figures of John Wesley and John Ray played a role in affirming the validity of his scientific interests and concerns for science education.

  11. Marxismo, comunicação e cultura - Raymond Williams e o materialismo cultural

    OpenAIRE

    Fábio Palácio de Azevedo

    2014-01-01

    O materialismo cultural é uma abordagem metodológica contemporânea em Teoria Cultural. Trata-se de \\"uma teoria das especificidades da produção material de cultura e literatura dentro do materialismo histórico\\", conforme define Raymond Williams (1921-1988), um dos principais nomes ligados a essa perspectiva. Fundador da tradição britânica dos estudos culturais, Williams concebe a cultura, na contramão da crítica literária tradicional - de base romântico-idealista -, como produção material da...

  12. Syndromes microdélétionnels (syndrome de Williams et syndrome ...

    African Journals Online (AJOL)

    Actuellement la FISH est la technique de choix pour rechercher ces syndromes. Plusieurs syndromes microdélétionnels peuvent être confirmés aisément, les plus recherchés sont Le syndrome de Williams (microdélétion en 7q11.23) et le syndrome de la délétion 22q11 (microdélétion en 22q11.2). Le syndrome de Williams ...

  13. Quantum corrections to the Weizsaecker-Williams gluon distribution function at small x

    International Nuclear Information System (INIS)

    Ayala, A.; Jalilian-Marian, J.; McLerran, L.; Venugopalan, R.

    1996-01-01

    We compute the quantum corrections to the gluon distribution function in the background of a non-Abelian Weizsaecker-Williams field. These corrections are valid to all orders in the effective coupling α s μ, where μ 2 denotes the average valence quark color charge squared per unit area. We find ln(1/x) logarithmic corrections to the classical gluon distribution function. The one-loop corrections to the classical Weizsaecker-Williams field do not contribute to these singular terms in the distribution function. Their effect is to cause the running of α s . copyright 1995 The American Physical Society

  14. William and Caroline Herschel pioneers in late 18th-century astronomy

    CERN Document Server

    Hoskin, Michael

    2013-01-01

    This beautifully structured book presents the essentials of William and Caroline Herschel's pioneering achievements in late 18th-century astronomy. Michael Hoskin shows that William Herschel was the first observational cosmologist and one of the first observers to attack the sidereal universe beyond the solar system:Herschel built instruments far better than any being used at the royal observatory. Aided by his sister Caroline, he commenced a great systematic survey that led to his discovery of Uranus in 1781.Unlike observers before him, whose telescopes did not reveal them as astronomical obj

  15. The Role of Spiral Multidetector Dynamic CT in the Study of Williams-Campbell Syndrome

    Energy Technology Data Exchange (ETDEWEB)

    Scioscio, V. di; Zompatori, M.; Mistura, I.; Montanari, P.; Santilli, L.; Luccaroni, R.; Sverzellati, N. [Medical Univ. of Bologna, S. Orsola-Malpighi Policlinic (Italy). Dept. of Radiology

    2006-10-15

    Williams-Campbell syndrome is a cystic bronchiectatic disease secondary to deficiency or defect of cartilaginous plates in the wall of the airways. In the literature, two main forms are suggested: congenital and acquired (post-infectious). The most frequent symptoms are represented by recurrent pulmonary infections from childhood. Multislice spiral dynamic CT has a major role in the study of cystic pulmonary disease and in differentiating Williams-Campbell syndrome from the other causes of cystic bronchiectasis, in which even lung function tests can give deceptive results.

  16. Prototyping an Electronic Edition of William Blake’s Manuscript of Vala, or the Four Zoas: A Progress Report

    Directory of Open Access Journals (Sweden)

    Morris Eaves

    2015-12-01

    Full Text Available This article describes the recent experiments undertaken by the 'William Blake Archive' in preparing a digital edition of 'Vala, or the Four Zoas', one of Blake’s most materially challenging works. The aim is to provide users with multiple tools for analysing Blake’s messy and mysterious manuscript: a high-quality image of the manuscript page paired with a dynamic transcription that allows readers to choose the level of detail they want for understanding what it is, precisely, they are looking at. However, the existing encoding standards and display were revealed to be totally inadequate by the complexity of 'The Four Zoas', and early models were almost impossible to read and understand. The article traces the journey towards the latest prototype as the team try to strike a balance between detail and accessibility, description and interpretation, readability and reliability, and established conventions and new approaches. ' ''

  17. Doing Duo – a Case Study of Entrainment in William Forsythe’s Choreography Duo

    Directory of Open Access Journals (Sweden)

    Elizabeth eWaterhouse

    2014-10-01

    Full Text Available Entrainment theory focuses on processes in which interacting (i.e. coupled rhythmic systems stabilize, producing synchronization in the ideal sense, and forms of phase related rhythmic coordination in complex cases. In human action, entrainment involves spatiotemporal and social aspects, characterizing the meaningful activities of music, dance, and communication. How can the phenomenon of human entrainment be meaningfully studied in complex situations such as dance? We present an in-progress case study of entrainment in William Forsythe's choreography Duo, a duet in which coordinated rhythmic activity is achieved without an external musical beat and without touch-based interaction. Using concepts of entrainment from different disciplines as well as insight from Duo performer Riley Watts, we question definitions of entrainment in the context of dance. The functions of chorusing, turn-taking, complementary action, cues and alignments are discussed and linked to supporting annotated video material. While Duo challenges the definition of entrainment in dance as coordinated response to an external musical or rhythmic signal, it supports the definition of entrainment as coordinated interplay of motion and sound production by active agents (i.e., dancers in the field. Agreeing that human entrainment should be studied on multiple levels, we suggest that entrainment between the dancers in Duo is elastic in time and a propose how to test this hypothesis empirically. We do not claim that our proposed model of elasticity is applicable to all forms of human entrainment nor to all to examples of entrainment in dance. Rather, we suggest studying higher order phase correction (the stabilizing tendency of entrainment as a potential aspect to be incorporated into other models.

  18. 77 FR 32625 - William J. Stevenson, Estate of Lynn E. Stevenson, Black Canyon Bliss, LLC; Notice of Application...

    Science.gov (United States)

    2012-06-01

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 8866-010] William J. Stevenson, Estate of Lynn E. Stevenson, Black Canyon Bliss, LLC; Notice of Application for Transfer of License, and Soliciting Comments and Motions To Intervene On April 23, 2012, William J. Stevenson, Estate...

  19. 77 FR 58819 - Notice of Submission for OMB Review; Federal Student Aid; William D. Ford Federal Direct Loan...

    Science.gov (United States)

    2012-09-24

    ... DEPARTMENT OF EDUCATION Notice of Submission for OMB Review; Federal Student Aid; William D. Ford Federal Direct Loan Program General Forbearance Request SUMMARY: Borrowers who receive loans through the William D. Ford Federal Direct Loan Program will use this form to request forbearance on their loans when...

  20. 78 FR 49749 - Williams Olefins Feedstock Pipelines, L.L.C.; Notice of Petition for Declaratory Order

    Science.gov (United States)

    2013-08-15

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. OR13-29-000] Williams Olefins Feedstock Pipelines, L.L.C.; Notice of Petition for Declaratory Order Take notice that on August 6...)(2)(2012), Williams Olefins Feedstock Pipelines, L.L.C., filed a petition requesting a declaratory...

  1. Behavioral Profiles of Children with Williams Syndrome from Spain and the United States: Cross-Cultural Similarities and Differences

    Science.gov (United States)

    Pérez-García, Débora; Brun-Gasca, Carme; Pérez-Jurado, Luis A.; Mervis, Carolyn B.

    2017-01-01

    To identify similarities and differences in the behavioral profile of children with Williams syndrome from Spain (n = 53) and the United States (n = 145), we asked parents of 6- to 14-year-olds with Williams syndrome to complete the Child Behavior Checklist 6-18. The distribution of raw scores was significantly higher for the Spanish sample than…

  2. Nucleon emission via electromagnetic excitation in relativistic nucleus-nucleus collisions: Reanalysis of the Weizsaecker-Williams method

    International Nuclear Information System (INIS)

    Norbury, J.W.

    1989-01-01

    Previous analyses of the comparison of Weizsaecker-Williams theory to experiment for nucleon emission via electromagnetic excitations in nucleus-nucleus collisions have not been definitive because of different assumptions concerning the value of the minimum impact parameter. This situation is corrected by providing criteria that allow one to make definitive statements concerning agreement or disagreement between Weizsaescker-Williams theory and experiment

  3. Brief Report: Repetitive Behaviour Profiles in Williams Syndrome: Cross Syndrome Comparisons with Prader-Willi and Down Syndromes

    Science.gov (United States)

    Royston, R.; Oliver, C.; Moss, J.; Adams, D.; Berg, K.; Burbidge, C.; Howlin, P.; Nelson, L.; Stinton, C.; Waite, J.

    2018-01-01

    This study describes the profile of repetitive behaviour in individuals with Williams syndrome, utilising cross-syndrome comparisons with people with Prader-Willi and Down syndromes. The Repetitive Behaviour Questionnaire was administered to caregivers of adults with Williams (n = 96), Prader-Willi (n = 103) and Down (n = 78) syndromes. There were…

  4. A common polymorphism in a Williams syndrome gene predicts amygdala reactivity and extraversion in healthy adults

    Science.gov (United States)

    Swartz, Johnna R.; Waller, Rebecca; Bogdan, Ryan; Knodt, Annchen R.; Sabhlok, Aditi; Hyde, Luke W.; Hariri, Ahmad R.

    2015-01-01

    Background Williams syndrome (WS), a genetic disorder resulting from hemizygous microdeletion of chromosome 7q11.23, has emerged as a model for identifying the genetic architecture of socioemotional behavior. Recently, common polymorphisms in GTF2I, which is found within the WS microdeletion, have been associated with reduced social anxiety in the general population. Identifying neural phenotypes affected by these polymorphisms will help advance our understanding not only of this specific genetic association but also the broader neurogenetic mechanisms of variability in socioemotional behavior. Methods Through an ongoing parent protocol, the Duke Neurogenetics Study, we measured threat-related amygdala reactivity to fearful and angry facial expressions using functional MRI (fMRI), assessed trait personality using the Revised NEO Personality Inventory, and imputed GTF2I rs13227433 from saliva-derived DNA using custom Illumina arrays. Participants included 808 non-Hispanic Caucasian, African American, and Asian university students. Results The GTF2I rs13227433 AA genotype, previously associated with lower social anxiety, predicted decreased threat-related amygdala reactivity. An indirect effect of GTF2I genotype on the warmth facet of extraversion was mediated by decreased threat-related amygdala reactivity in women but not men. Conclusions A common polymorphism in the WS gene GTF2I associated with reduced social anxiety predicts decreased threat-related amygdala reactivity, which mediates an association between genotype and increased warmth in women. These results are consistent with reduced threat-related amygdala reactivity in WS and suggest that common variation in GTF2I contributes to broader variability in socioemotional brain function and behavior, with implications for understanding the neurogenetic bases of WS as well as social anxiety. PMID:26853120

  5. Leftward lateralization of auditory cortex underlies holistic sound perception in Williams syndrome.

    Directory of Open Access Journals (Sweden)

    Martina Wengenroth

    Full Text Available BACKGROUND: Individuals with the rare genetic disorder Williams-Beuren syndrome (WS are known for their characteristic auditory phenotype including strong affinity to music and sounds. In this work we attempted to pinpoint a neural substrate for the characteristic musicality in WS individuals by studying the structure-function relationship of their auditory cortex. Since WS subjects had only minor musical training due to psychomotor constraints we hypothesized that any changes compared to the control group would reflect the contribution of genetic factors to auditory processing and musicality. METHODOLOGY/PRINCIPAL FINDINGS: Using psychoacoustics, magnetoencephalography and magnetic resonance imaging, we show that WS individuals exhibit extreme and almost exclusive holistic sound perception, which stands in marked contrast to the even distribution of this trait in the general population. Functionally, this was reflected by increased amplitudes of left auditory evoked fields. On the structural level, volume of the left auditory cortex was 2.2-fold increased in WS subjects as compared to control subjects. Equivalent volumes of the auditory cortex have been previously reported for professional musicians. CONCLUSIONS/SIGNIFICANCE: There has been an ongoing debate in the neuroscience community as to whether increased gray matter of the auditory cortex in musicians is attributable to the amount of training or innate disposition. In this study musical education of WS subjects was negligible and control subjects were carefully matched for this parameter. Therefore our results not only unravel the neural substrate for this particular auditory phenotype, but in addition propose WS as a unique genetic model for training-independent auditory system properties.

  6. Distribution of juvenile Pacific herring relative to environmental and geospatial factors in Prince William Sound, Alaska

    Science.gov (United States)

    Lewandoski, Sean; Bishop, Mary Anne

    2018-01-01

    Documenting distribution patterns of juvenile Pacific herring (Clupea pallasii) can clarify habitat preferences and provide insight into ecological factors influencing early life survival. However, few analyses relating juvenile Pacific herring density to habitat characteristics have been conducted. We sampled age-0 Pacific herring in nine bays and fjords distributed throughout Alaska's Prince William Sound during November over a 3-year period (2013-2015) and investigated associations between catch rate and habitat covariates using generalized linear mixed models. Our results indicated that the night-time distribution of age-0 Pacific herring in the pelagic environment was influenced by proximity to eelgrass (Zostera marina) beds, salinity, and water depth. Age-0 Pacific herring catch rate was negatively associated with tow depth, with herring favoring shallower water across the range of depths sampled (7.2-35.4 m). In addition, Pacific herring distribution was positively associated with fresher water within the sampled salinity gradient (24.1-32.3 psu) and proximity to eelgrass beds. Seasonal changes in juvenile Pacific herring distribution were investigated by sampling one bay over a seven month period (October-April). Age-0 Pacific herring tended to remain in the inner bay region throughout the seven months, while age-1 Pacific herring had shifted from the inner to the outer bay by spring (March-April). Additionally, catch rate of age-0 Pacific herring in areas where ice breakup had just occurred was higher than in open water, suggesting that age-0 herring preferentially select ice-covered habitats when available. Based on our results we recommend that habitat preferences of age-0 Pacific herring should be considered in the development of Pacific herring year-class strength indices from catch data.

  7. First 2017-total-eclipse results from the Williams College team

    Science.gov (United States)

    Pasachoff, J.; Dantowitz, R.; Rusin, V.; Seiradakis, J. H.; Voulgaris, A.; Seaton, D. B.; Davis, A. B.; Lu, M.; Sliski, D.; Ladd, E. F.; Economou, T.; Peñaloza-Murillo, M. A.; Nagle-McNaughton, T.

    2017-12-01

    We report on a wide range of observations we carried out during the total solar eclipse of August 21, 2017. Our main site was on the campus of Willamette University, Salem, Oregon, at which we had a variety of telescopes, spectrographs, cameras, a grism, and terrestrial-atmospheric measuring devices. Our goals included differentiating between models of coronal heating through measuring power-spectra of coronal loops in the [Fe XIV] and [Fe X] emission lines at multi-Hertz cadence with a frame-transfer CCD and otherwise; following coronal structure over the solar-activity cycle; comparing the results of a full-MHD prediction with actual coronal streamers; studying the dynamics of coronal plumes given the minimum phase of the solar-activity cycle; measuring the variation of the corona over the solar-activity cycle from our continuing measurements of the green-line/red-line intensity ratio; studying a variety of additional coronal emisson lines; high-resolution coronal imaging compared with overlapping images from space coronagraphs aboard SoHO and STEREO; comparing with AIA/SDO, HMO/SDO, SUVI/GOES-16, and SWAP/PROBA2 space images; and more. Our research has been supported in large part by grants from the Committee for Research and Exploration of the National Geographic Society and from the Solar Terrestrial Program of the Atmospheric and Geospace Sciences Division of the National Science Foundation, with additional support from Sigma Xi. Additional support for undergraduate participation came from the NSF, the NASA Massachusetts Space Grant Consortium, and the Clare Booth Luce Foundation, with travel support from the Freeman Foote Fund, the Rob Spring Fund, the Brandi Fund, and other sources at Williams College.

  8. Listen to the Sound of the Quiet American: John Williams's Stoner

    Directory of Open Access Journals (Sweden)

    Maureen Clark

    2017-06-01

    Full Text Available 'Stoner' (1965, John Williams’s third novel, questions and complicates mythologised versions of modern American identity and way of life. The story moves through two World Wars, the Great Depression following the Wall Street crash, and President Franklin D. Roosevelt’s New-Deal America, a prolonged time of social upheaval throughout the world. The book re-imagines stuff-of-dreams versions of the American cultural hero modelled on the image of the brash, risk-taking and economically-successful individual of the 1920s decade. The position mediated by the narrative is one of disillusionment with a nation more in step with passionate, impulsive actions associated with cultural heroism than with cool, astute consideration of possible destructive consequences. Confronted and brought into question is the presumption of silence as ineffectual resistance to the injustices that operate within public and private institutionalized power structures. At first glance, Williams’s eponymous hero, William Stoner’s, wont to quietly internalize, rather than loudly agitate against, conflict-driven social environments, appears to reaffirm this view. Portrayed as a decent man who thinks before he speaks, Stoner’s character proffers the idea that silence and care-full thought before acting can be constructive in the pursuit of a better, more balanced way of being in the world. This essay argues that Stoner’s habitual interiority functions as a political symbolic filter to challenge commonly-held impressions of heroism understood as a garrulous, action-based cultural code of behavior in the practice of everyday life.

  9. Oral histories in meteoritics and planetary science—XXIV: William K. Hartmann

    Science.gov (United States)

    Sears, Derek W. G.

    2014-06-01

    In this interview, William Hartmann (Bill, Fig. 1) describes how he was inspired as a teenager by a map of the Moon in an encyclopedia and by the paintings by Chesley Bonestell. Through the amateur journal "Strolling Astronomer," he shared his interests with other teenagers who became lifelong colleagues. At college, he participated in Project Moonwatch, observing early artificial satellites. In graduate school, under Gerard Kuiper, Bill discovered Mare Orientale and other large concentric lunar basin structures. In the 1960s and 1970s, he used crater densities to study surface ages and erosive/depositional effects, predicted the approximately 3.6 Gyr ages of the lunar maria before the Apollo samples, discovered the intense pre-mare lunar bombardment, deduced the youthful Martian volcanism as part of the Mariner 9 team, and proposed (with Don Davis) the giant impact model for lunar origin. In 1972, he helped found (what is now) the Planetary Science Institute. From the late 1970s to early 1990s, Bill worked mostly with Dale Cruikshank and Dave Tholen at Mauna Kea Observatory, helping to break down the Victorian paradigm that separated comets and asteroids, and determining the approximately 4% albedo of comet nuclei. Most recently, Bill has worked with the imaging teams for several additional Mars missions. He has written three college textbooks and, since the 1970s, after painting illustrations for his textbooks, has devoted part of his time to painting, having had several exhibitions. He has also published two novels. Bill Hartmann won the 2010 Barringer Award for impact studies and the first Carl Sagan Award for outreach in 1997.

  10. Oxytocin and vasopressin are dysregulated in Williams Syndrome, a genetic disorder affecting social behavior.

    Directory of Open Access Journals (Sweden)

    Li Dai

    Full Text Available The molecular and neural mechanisms regulating human social-emotional behaviors are fundamentally important but largely unknown; unraveling these requires a genetic systems neuroscience analysis of human models. Williams Syndrome (WS, a condition caused by deletion of ~28 genes, is associated with a gregarious personality, strong drive to approach strangers, difficult peer interactions, and attraction to music. WS provides a unique opportunity to identify endogenous human gene-behavior mechanisms. Social neuropeptides including oxytocin (OT and arginine vasopressin (AVP regulate reproductive and social behaviors in mammals, and we reasoned that these might mediate the features of WS. Here we established blood levels of OT and AVP in WS and controls at baseline, and at multiple timepoints following a positive emotional intervention (music, and a negative physical stressor (cold. We also related these levels to standardized indices of social behavior. Results revealed significantly higher median levels of OT in WS versus controls at baseline, with a less marked increase in AVP. Further, in WS, OT and AVP increased in response to music and to cold, with greater variability and an amplified peak release compared to controls. In WS, baseline OT but not AVP, was correlated positively with approach, but negatively with adaptive social behaviors. These results indicate that WS deleted genes perturb hypothalamic-pituitary release not only of OT but also of AVP, implicating more complex neuropeptide circuitry for WS features and providing evidence for their roles in endogenous regulation of human social behavior. The data suggest a possible biological basis for amygdalar involvement, for increased anxiety, and for the paradox of increased approach but poor social relationships in WS. They also offer insight for translating genetic and neuroendocrine knowledge into treatments for disorders of social behavior.

  11. In memoriam - William Toshio (Tosh) Yasutake, 1922-2016

    Science.gov (United States)

    Elliott, Diane G.; Winton, James R.

    2017-01-01

    William Toshio (Tosh) Yasutake, 1922-2016 passed away peacefully at home on December 12, 2016, at the age of 94. He is survived by Fumi, his wife of 66 years, as well as four children and six grandchildren. With his death, the fish health community has lost an outstanding scientist as well as a kind, unassuming, and wonderful human being. Tosh was born on June 10, 1922, in Seattle, Washington, to Jack and Hide Yasutake. He was in his first year of studies at the University of Washington when Pearl Harbor was attacked by Imperial Japan on December 7, 1941. Following the attack, Tosh and his family (father, mother, sister, and two brothers) were among the 110,000–120,000 people of Japanese ancestry who were forced from their homes on the Pacific coast and incarcerated in internment camps in the interior. In June 1942, Tosh enlisted in the U.S. Army, serving as an unarmed combat medic in the famed 442nd Regimental Combat Team, the most decorated unit for its size and length of service in the history of American warfare. Wounded in October 1944 during the Vosges Mountains campaign near Bruyères, France, Tosh was evacuated and missed the ensuing battle to rescue the “Lost Battalion,” at which his replacement was killed. Tosh returned to action in Italy in February 1945 and served until the end of the war in Europe, earning both a Purple Heart and a Bronze Star for bravery. In October 2010, the Congressional Gold Medal was awarded to the 442nd Regimental Combat Team, and in 2012 the surviving members were made chevaliers of the French Légion d’Honneur for actions contributing to the liberation of France in World War II.After the war, Tosh returned to the University of Washington on the GI Bill and received a B.S. degree in zoology in 1951. In 1953 he began his research career at the U.S. Fish and Wildlife Service’s Western Fish Nutrition Laboratory at Cook, Washington, where he conducted pioneering research on nutritional fish diseases with John Halver. Tosh

  12. Nitrogen and Phosphorus Biomass-Kinetic Model for Chlorella vulgaris in a Biofuel Production Scheme

    Science.gov (United States)

    2010-03-01

    NITROGEN AND PHOSPHORUS BIOMASS-KINETIC MODEL FOR CHLORELLA VULGARIS IN A BIOFUEL PRODUCTION SCHEME THESIS William M. Rowley, Major...States Government. AFIT/GES/ENV/10-M04 NITROGEN AND PHOSPHORUS BIOMASS-KINETIC MODEL FOR CHLORELLA VULGARIS IN A BIOFUEL...MODEL FOR CHLORELLA VULGARIS IN A BIOFUEL PRODUCTION SCHEME William M. Rowley, BS Major, USMC Approved

  13. Inventing Orientation and Mobility Techniques and Teaching Methods: A Conversation with Russell Williams

    Science.gov (United States)

    Welsh, Richard L.

    2005-01-01

    Russell C. Williams was a key figure in the progression of orientation and mobility from the Army's immediate response to the servicemen and women who lost their sight during World War II to a recognized profession delivering individualized instruction to visually impaired people throughout the world. Blinded in combat while serving in the U.S.…

  14. Human versus Non-Human Face Processing: Evidence from Williams Syndrome

    Science.gov (United States)

    Santos, Andreia; Rosset, Delphine; Deruelle, Christine

    2009-01-01

    Increased motivation towards social stimuli in Williams syndrome (WS) led us to hypothesize that a face's human status would have greater impact than face's orientation on WS' face processing abilities. Twenty-nine individuals with WS were asked to categorize facial emotion expressions in real, human cartoon and non-human cartoon faces presented…

  15. Case report of sudden death in a child with Williams syndrome ...

    African Journals Online (AJOL)

    Williams syndrome is a neurodevelopmental disorder characterized by distinctive personality traits, facial features (so called “elfin face”) and cardiac abnormalities, of which supravalvular aortic stenosis is the most common lesion found. The cause is a deletion of a group of genes on chromosome 7q11.23. Administration of ...

  16. Featural versus Configural Face Processing in a Rare Genetic Disorder: Williams Syndrome

    Science.gov (United States)

    Isaac, L.; Lincoln, A.

    2011-01-01

    Background: Williams syndrome (WMS) is a rare genetic disorder with an estimated prevalence of 1 in 20,000 live births. Among other characteristics, WMS has a distinctive cognitive profile with spared face processing and language skills that contrasts with impairment in the cognitive domains of spatial cognition, problem solving and planning. It…

  17. Williams Syndrome Hypersociability: A Neuropsychological Study of the Amygdala and Prefrontal Cortex Hypotheses

    Science.gov (United States)

    Capitao, Liliana; Sampaio, Adriana; Fernandez, Montse; Sousa, Nuno; Pinheiro, Ana; Goncalves, Oscar F.

    2011-01-01

    Individuals with Williams syndrome display indiscriminate approach towards strangers. Neuroimaging studies conducted so far have linked this social profile to structural and/or functional abnormalities in WS amygdala and prefrontal cortex. In this study, the neuropsychological hypotheses of amygdala and prefrontal cortex involvement in WS…

  18. Brief Report: Exploring the Relationship between Sensory Processing and Repetitive Behaviours in Williams Syndrome

    Science.gov (United States)

    Riby, Deborah M.; Janes, Emily; Rodgers, Jacqui

    2013-01-01

    This study explored the relationship between sensory processing abnormalities and repetitive behaviours in children with Williams Syndrome (WS; n = 21). This is a novel investigation bringing together two clinical phenomena for the first time in this neuro-developmental disorder. Parents completed the Sensory Profile (Short Form; Dunn in The…

  19. Dr William Farr of Shropshire (1807-1883): obstetric mortality and training.

    Science.gov (United States)

    Dunn, P M

    2002-07-01

    William Farr, chief statistician to the General Register Office for more than 40 years, was the most significant medical epidemiologist and statistician of the Victorian era. Often working behind the scenes, he helped to bring about many advances in hygiene and public health as well as developing a modern approach to the classification of disease and the collection and analysis of medical information data.

  20. A Voice from Mount Parnassus: The Autobiography of William E. Drake, 1903-1989. Second Edition.

    Science.gov (United States)

    Willers, Jack Conrad, Ed.

    This narrative chronicles the life of the nationally-known but controversial teacher educator, historian, and philosopher of education William E. Drake. Drake was the author of "American Education in Transition"; "The Intellectual Foundations of Modern Education"; and numerous articles and monographs. He taught for 50 years at…

  1. Sleep Patterns and Daytime Sleepiness in Adolescents and Young Adults with Williams Syndrome

    Science.gov (United States)

    Goldman, S. E.; Malow, B. A.; Newman, K. D.; Roof, E.; Dykens, E. M.

    2009-01-01

    Background: Sleep disorders are common in individuals with neurodevelopmental disorders and may adversely affect daytime functioning. Children with Williams syndrome have been reported to have disturbed sleep; however, no studies have been performed to determine if these problems continue into adolescence and adulthood. Methods: This study…

  2. Periodic Reactions: The Early Works of William C. Bray and Alfred J. Lotka

    Science.gov (United States)

    Cervellati, Rinaldo; Greco, Emanuela

    2017-01-01

    Oscillating chemical reactions in the homogeneous phase have been studied intensively only since the mid-1960s, but they were known since 1920, having as forerunners the chemist William C. Bray and an "atypical" chemist Alfred J. Lotka. This contribution is the result of a careful reading of their literature and patient research into…

  3. The Revolt of the Object : Animated Drawings and the Colonial Archive: William Kentridge's Black Box Theatre

    NARCIS (Netherlands)

    Buikema, R.L.

    2016-01-01

    When South African visual artist William Kentridge accepted the yearly assignment of the German Guggenheim Foundation, he decided for that occasion to thematize the link between Germany and Africa's colonial histories. In particular he decided to highlight the under-researched history of the

  4. Interpretation of Ambiguous Situations: Evidence for a Dissociation between Social and Physical Threat in Williams Syndrome

    Science.gov (United States)

    Dodd, Helen F.; Porter, Melanie A.

    2011-01-01

    Williams syndrome (WS) is associated with an unusual profile of anxiety, characterised by increased rates of non-social anxiety but not social anxiety (Dodd and Porter, J Ment Health Res Intellect Disabil 2(2):89-109, "2009"). The present research examines whether this profile of anxiety is associated with an interpretation bias for ambiguous…

  5. The Impact of Personality on History: An Interview with William L. Shirer.

    Science.gov (United States)

    Social Education, 1983

    1983-01-01

    William L. Shirer, author of Rise and Fall of the Third Reich, discusses a wide variety of subjects, including the personalities of Roosevelt and Hitler, why the Germans succumbed to Nazism, McCarthyism in the United States, and the heroic resistance of the Russians to German invasion. (CS)

  6. Welcome Donald Trump, Baltics! The presidency to endure? / Mark Hertling, William E. Pomeranz ; intervjueeris Linas Jegelevicius

    Index Scriptorium Estoniae

    Hertling, Mark

    2017-01-01

    USA Euroopa vägede endine ülem kindralleitnant Mark Hertlingi ja Kennani Instituudi asedirektor William E. Pomeranz analüüsivad Ameerika Ühendriikide uue presidendi Tonald Trumpi ametisseasumise võimalikku mõju Balti riikide julgeolekule

  7. Diurnal Cortisol Profile in Williams Syndrome in Novel and Familiar Settings

    Science.gov (United States)

    Lense, Miriam Diane; Tomarken, Andrew J.; Dykens, Elisabeth M.

    2013-01-01

    Williams syndrome (WS) is a neurodevelopmental genetic disorder associated with high rates of anxiety and social issues. We examined diurnal cortisol, a biomarker of the stress response, in adults with WS in novel and familiar settings, and compared these profiles to typically developing (TD) adults. WS and TD participants had similar profiles in…

  8. William Bennett and the "Good War" against Drugs: Doublespeak and the Bush Administration's Hidden Agenda.

    Science.gov (United States)

    Massey, Tom

    This paper contends that former Secretary of Education William Bennett's "war on drugs" (he now directs the government's campaign against drugs) is not being waged against those who sell and use drugs, but against the civil liberties of everyone. The paper maintains that under the guise of ridding society of what President Bush called…

  9. Alternative Strategies to William Bennett's Plan for a National War on Drugs: A Comprehensive Systems Approach.

    Science.gov (United States)

    D'Andrea, Michael

    As this country's first appointed "drug czar," William Bennett developed a set of proposals for a national campaign against drug abuse. These included: expanding the national prison capacity by 85 percent; providing additional fiscal support for states and local areas that adopt anti-drug laws; and increasing the availablility of…

  10. Featural versus configural face processing in a rare genetic disorder: Williams syndrome

    NARCIS (Netherlands)

    Isaac, L.; Lincoln, A.

    2011-01-01

    Background Williams syndrome (WMS) is a rare genetic disorder with an estimated prevalence of 1 in 20 000 live births. Among other characteristics, WMS has a distinctive cognitive profile with spared face processing and language skills that contrasts with impairment in the cognitive domains of

  11. "I Had Made a Mistake": William H. Kilpatrick and the Project Method

    Science.gov (United States)

    Knoll, Michael

    2012-01-01

    Background/Context: William H. Kilpatrick is known worldwide as "Mr. Project Method." Despite considerable scholarship by Lawrence A. Cremin, Herbert M. Kliebard, Milton A. Bleeke, John A. Beineke, and others, the origin of Kilpatrick's celebrated paper of 1918 has never been explored in depth and its historical context. Focus of Study:…

  12. William Graham Brooke (1835-1907): Advocate of Girls' Superior Schooling in Nineteenth-Century Ireland

    Science.gov (United States)

    McCormack, Christopher F.

    2015-01-01

    This paper examines the role of William Graham Brooke as advocate of women's higher education and access to university. His work as advocate is considered against the religious, political, social and economic backdrop of late nineteenth century Ireland. A barrister, as Clerk in the Lord Chancellor's office, he was centrally involved in the…

  13. Cognitive, Linguistic and Adaptive Functioning in Williams Syndrome: Trajectories from Early to Middle Adulthood

    Science.gov (United States)

    Howlin, Patricia; Elison, Sarah; Udwin, Orlee; Stinton, Christopher

    2010-01-01

    Background: Little is known about trajectories of cognitive functioning as individuals with Williams syndrome (WS) move though adulthood. Method: The present study investigated cognitive, linguistic and adaptive functioning in adults with WS aged 19-55 years, using both cross-sectional and longitudinal approaches. Results: Data from the…

  14. Elastins from patients with Williams-Beuren syndrome and healthy individuals differ on the molecular level

    DEFF Research Database (Denmark)

    Heinz, Andrea; Huertas, Angela C Mora; Schräder, Christoph U

    2016-01-01

    Williams-Beuren syndrome (WBS) is a congenital disorder, which involves the heterozygous deletion of the elastin gene and other genes on chromosome 7. Clinical symptoms that are associated with hemizygosity of the essential extracellular matrix protein elastin include premature aging of the skin...

  15. Brief Report: Major Depressive Disorder with Psychotic Features in Williams Syndrome--A Case Series

    Science.gov (United States)

    Valdes, Francisca; Keary, Christopher J.; Mullett, Jennifer E.; Palumbo, Michelle L.; Waxler, Jessica L.; Pober, Barbara R.; McDougle, Christopher J.

    2018-01-01

    Descriptions of individuals with Williams syndrome (WS) and co-morbid major depressive disorder (MDD) with psychotic features have not appeared in the literature. In addition to reviewing previous reports of psychotic symptoms in persons with WS, this paper introduces clinical histories and therapeutic management strategies for three previously…

  16. Toddlers with Williams Syndrome Process Upright but Not Inverted Faces Holistically

    Science.gov (United States)

    Cashon, Cara H.; Ha, Oh-Ryeong; DeNicola, Christopher A.; Mervis, Carolyn B.

    2013-01-01

    Holistic processing of upright, but not inverted, faces is a marker of perceptual expertise for faces. This pattern is shown by typically developing individuals beginning at age 7 months. Williams syndrome (WS) is a rare neurogenetic developmental disorder characterized by extreme interest in faces from a very young age. Research on the effects of…

  17. Developments in fiber-positioning technology for the WEAVE instrument at the William Herschel Telescope

    NARCIS (Netherlands)

    Schallig, Ellen; Lewis, Ian J.; Gilbert, James; Dalton, Gavin; Brock, Matthew; Abrams, Don Carlos; Middleton, Kevin; Aguerri, J. Alfonso L.; Bonifacio, Piercarlo; Carrasco, Esperanza; Trager, Scott C.; Vallenari, Antonella

    2016-01-01

    WEAVE is the next-generation wide-field optical spectroscopy facility for the William Herschel Telescope (WHT) on La Palma in the Canary Islands, Spain. It is a multi-object "pick-and-place" fibre-fed spectrograph with a 1000 fibre multiplex behind a new dedicated 2° prime focus corrector. The WEAVE

  18. Fair Use under the 1976 Copyright Act: The Legacy of Williams and Wilkins for Librarians.

    Science.gov (United States)

    Billings, Roger D., Jr.

    1983-01-01

    Comments on court cases dealing with copyrighted materials of special interest to librarians highlight Williams and Wilkins case, Sony case dealing with videocopying, computer programs and databases, government and legal materials in public domain, musical works, and four factors of Section 107 (fair use) of 1976 Copyright Law. (109 references)…

  19. William Golding's Iconoclastic Views about the Neanderthal Man in "The Inheritors"

    Science.gov (United States)

    Youssef, Sayed Mohammed

    2016-01-01

    William Golding has been identified as a nonconformist whose opinions always go contrary to what is customarily accepted or established. This is shown in all his novels, more specifically "The Inheritors", in which he defies long established opinions held by anthropologists, historians, archaeologists as well as many others about the…

  20. 76 FR 13667 - Commercial Furniture Group, Inc., Formerly Known as Falcon Products, Inc., Shelby Williams, Howe...

    Science.gov (United States)

    2011-03-14

    ... Furniture Group, Inc., Formerly Known as Falcon Products, Inc., Shelby Williams, Howe and Thonet, Including On-Site Leased Workers From Staffing Solutions, Morristown, TN, and Commercial Furniture Group, Inc... Commercial Furniture Group, Inc., including on-site leased workers from Staffing Solutions, Morristown...

  1. Caregiver Survey of Pharmacotherapy to Treat Attention Deficit/Hyperactivity Disorder in Individuals with Williams Syndrome

    Science.gov (United States)

    Martens, Marilee A.; Seyfer, Daisha L.; Andridge, Rebecca R.; Foster, Jessica E. A.; McClure, Kelsey E.; Coury, Daniel L.

    2013-01-01

    Williams syndrome (WS) is a genetic condition characterized by a unique neurocognitive and behavioral profile, including increased incidence of attention deficit/hyperactivity disorder (ADHD). The purpose of the present study was to examine the perceived helpfulness and side effects of medications used to treat ADHD (methylphenidate class,…

  2. William H. Taft High School Project HOLA 1984-1985. O.E.A. Evaluation Report.

    Science.gov (United States)

    New York City Board of Education, Brooklyn. Office of Educational Assessment.

    In 1984-85, Project HOLA was in its second year of funding at William H. Taft High School in the Bronx, New York. HOLA serves Spanish-speaking students of limited English proficiency (LEP). Project goals include speedy acquisition of English skills, orientation to life in America, maintenance and improvement of Spanish skills and cultural…

  3. William H. Taft High School Project HOLA, 1985-1986. OEA Evaluation Report.

    Science.gov (United States)

    New York City Board of Education, Brooklyn. Office of Educational Assessment.

    Project HOLA at William H. Taft High School (Bronx, New York) assists foreign-born and Puerto Rican-born students to quickly assists foreign- and Puerto Rican-born students to quickly acquire English language skills and an American cultural orientation; to maintain or improve their Spanish language skills and cultural knowledge; and to be…

  4. William H. Taft High School Project HOLA, 1986-1987. OEA Evaluation Report.

    Science.gov (United States)

    Martinez, Ana L.; And Others

    In its fourth year of Title VII funding, Project HOLA at William H. Taft High School served 383 Spanish-speaking students of limited English proficiency from low-income families. The program's goals were to develop English language skills for mainstreaming, to develop an understanding and awareness of American culture and society, to develop…

  5. A Comparison between Linguistic Skills and Socio-Communicative Abilities in Williams Syndrome

    Science.gov (United States)

    Alfieri, P.; Menghini, D.; Marotta, L.; De Peppo, L.; Ravà, L.; Salvaguardia, F.; Varuzza, C.; Vicari, S.

    2017-01-01

    Background: Individuals with Williams syndrome (WS) show a disharmonic linguistic profile with a clear pattern of strengths and weaknesses. Despite their sociable nature, atypical socio-communicative abilities and deficits in communication and relationship with others have been found. Aim: The aim of the present study was to investigate whether…

  6. David Cronenberg ja William S. Burroughs kutsuvad teid lantshile / Aare Ermel

    Index Scriptorium Estoniae

    Ermel, Aare, 1957-2013

    1999-01-01

    Mängufilm "Alasti eine" ("Naked Lunch") William S. Burroughs' teose järgi : režissöör ja stsenarist David Cronenberg : Suurbritannia - Kanada 1991. Lähemalt režissööri kohta. Ka Nädal nr. 35, lk. 29

  7. Attention in Williams Syndrome and Down's Syndrome: Performance on the New Early Childhood Attention Battery

    Science.gov (United States)

    Breckenridge, Kate; Braddick, Oliver; Anker, Shirley; Woodhouse, Margaret; Atkinson, Janette

    2013-01-01

    Attentional problems are commonly reported as a feature of the behavioural profile in both Williams syndrome (WS) and Down's syndrome (DS). Recent studies have begun to investigate these impairments empirically, acknowledging the need for an approach that considers cross-syndrome comparisons and developmental changes across the different component…

  8. Good Work and Aesthetic Education: William Morris, the Arts and Crafts Movement, and beyond

    Science.gov (United States)

    Petts, Jeffrey

    2008-01-01

    A notion of "good work," derived from William Morris and the Arts and Crafts Movement but also part of a wider tradition in philosophy (associated with pragmatism and Everyday Aesthetics) understanding the global significance of, and opportunities for, aesthetic experience, grounds both art making and appreciation in the organization of labor…

  9. Viewing Social Scenes: A Visual Scan-Path Study Comparing Fragile X Syndrome and Williams Syndrome

    Science.gov (United States)

    Williams, Tracey A.; Porter, Melanie A.; Langdon, Robyn

    2013-01-01

    Fragile X syndrome (FXS) and Williams syndrome (WS) are both genetic disorders which present with similar cognitive-behavioral problems, but distinct social phenotypes. Despite these social differences both syndromes display poor social relations which may result from abnormal social processing. This study aimed to manipulate the location of…

  10. A Noncomputerized Version of the Williams and Walker Stock Market Experiment in a Finance Course.

    Science.gov (United States)

    Bell, Christopher R.

    1993-01-01

    Asserts that the computerized stock market simulation described by Williams and Walker is complex and a better approach to teaching financial economics. Describes a noncomputerized version of the same teaching activity used to teach asset valuation to undergraduate financial economics students. (CFR)

  11. Why bad Moods Matter. William James on Melancholy, Mystic Emotion, and the Meaning of Life

    NARCIS (Netherlands)

    H.J. Pott (Heleen J.)

    2017-01-01

    textabstractWilliam James’s reputation in the field of emotion research is based on his early psychological writings where he defines emotions as ‘feelings of bodily changes’. In his later work, particularly in his study of mystic emotion (1902), James comes up with what looks like a completely

  12. Parent and Teacher Perspectives about Problem Behavior in Children with Williams Syndrome

    Science.gov (United States)

    Klein-Tasman, Bonita P.; Lira, Ernesto N.; Li-Barber, Kirsten T.; Gallo, Frank J.; Brei, Natalie G.

    2015-01-01

    Problem behavior of 52 children with Williams syndrome ages 6 to 17 years old was examined based on both parent and teacher report. Generally good inter-rater agreement was found. Common areas of problem behavior based both on parent and teacher report included attention problems, anxiety difficulties, repetitive behaviors (e.g., obsessions,…

  13. Developmental Trajectories of Structural and Pragmatic Language Skills in School-Aged Children with Williams Syndrome

    Science.gov (United States)

    Van Den Heuvel, E.; Manders, E.; Swillen, A.; Zink, I.

    2016-01-01

    Background: This study aimed to compare developmental courses of structural and pragmatic language skills in school-aged children with Williams syndrome (WS) and children with idiopathic intellectual disability (IID). Comparison of these language trajectories could highlight syndrome-specific developmental features. Method: Twelve monolingual…

  14. Pathways to Language: A Naturalistic Study of Children with Williams Syndrome and Children with Down Syndrome

    Science.gov (United States)

    Levy, Yonata; Eilam, Ariela

    2013-01-01

    This is a naturalistic study of the development of language in Hebrew-speaking children with Williams syndrome (WS) and children with Down syndrome (DS), whose MLU extended from 1[multiplied by]0 to 4[multiplied by]4. Developmental curves over the entire span of data collection revealed minor differences between children with WS, children with DS,…

  15. Adaptive Behavior and Problem Behavior in Young Children with Williams Syndrome

    Science.gov (United States)

    Hahn, Laura J.; Fidler, Deborah J.; Hepburn, Susan L.

    2014-01-01

    The present study compares the adaptive behavior profile of 18 young children with Williams syndrome (WS) and a developmentally matched group of 19 children with developmental disabilities and examines the relationship between adaptive behavior and problem behaviors in WS. Parents completed the Vineland Adaptive Behavioral Scales--Interview…

  16. Errors of Measurement, Theory, and Public Policy. William H. Angoff Memorial Lecture Series

    Science.gov (United States)

    Kane, Michael

    2010-01-01

    The 12th annual William H. Angoff Memorial Lecture was presented by Dr. Michael T. Kane, ETS's (Educational Testing Service) Samuel J. Messick Chair in Test Validity and the former Director of Research at the National Conference of Bar Examiners. Dr. Kane argues that it is important for policymakers to recognize the impact of errors of measurement…

  17. Co-occurrence of a de novo Williams and 22q11.2 microdeletion syndromes.

    Science.gov (United States)

    Shukla, Anju; Mandal, Kausik; Patil, Siddaramappa J; Kishore, Yougal; Phadke, Shubha R; Girisha, Katta M

    2015-08-01

    We report on a child with de novo deletions involving the 7q11.23 (Williams syndrome) and 22q11.2 (Velocardiofacial/DiGeorge syndrome) regions. We describe the clinical features of this rare double microdeletion syndrome reported here for the first time. © 2015 Wiley Periodicals, Inc.

  18. Recognition of Emotional and Nonemotional Facial Expressions: A Comparison between Williams Syndrome and Autism

    Science.gov (United States)

    Lacroix, Agnes; Guidetti, Michele; Roge, Bernadette; Reilly, Judy

    2009-01-01

    The aim of our study was to compare two neurodevelopmental disorders (Williams syndrome and autism) in terms of the ability to recognize emotional and nonemotional facial expressions. The comparison of these two disorders is particularly relevant to the investigation of face processing and should contribute to a better understanding of social…

  19. Problem Behaviour and Psychosocial Functioning in Young Children with Williams Syndrome: Parent and Teacher Perspectives

    Science.gov (United States)

    Klein-Tasman, B. P.; Lee, K.

    2017-01-01

    Background: There is sparse literature about problem behaviour in young children with Williams syndrome (WS) and little consideration of the perspectives of multiple respondents. Methods: Problem behaviour of 35 children with WS ages 2 to 6 was examined based on both parent and teacher report using the Achenbach preschool forms. Results: The most…

  20. Williams syndrome deletions and duplications: Genetic windows to understanding anxiety, sociality, autism, and schizophrenia.

    Science.gov (United States)

    Crespi, Bernard J; Procyshyn, Tanya L

    2017-08-01

    We describe and evaluate an integrative hypothesis for helping to explain the major neurocognitive features of individuals with Williams syndrome region deletions and duplications. First, we demonstrate how the cognitive differences between Williams syndrome individuals, individuals with duplications of this region, and healthy individuals parallel the differences between individuals subject to effects of increased or decreased oxytocin. Second, we synthesize evidence showing that variation in expression of the gene GTF2I (General Transcription Factor II-I) underlies the primary social phenotypes of Williams syndrome and that common genetic variation in GTF2I mediates oxytocin reactivity, and its correlates, in healthy populations. Third, we describe findings relevant to the hypothesis that the GTF2I gene is subject to parent of origin effects whose behavioral expression fits with predictions from the kinship theory of genomic imprinting. Fourth, we describe how Williams syndrome can be considered, in part, as an autistic syndrome of Lorna Wing's 'active-but-odd' autism subtype, in contrast to associations of duplications with both schizophrenia and autism. Copyright © 2017 Elsevier Ltd. All rights reserved.

  1. 77 FR 2242 - Radio Broadcasting Services; Ehrenberg, First Mesa, Kachina Village, Wickenburg, and Williams, AZ...

    Science.gov (United States)

    2012-01-17

    ... FEDERAL COMMUNICATIONS COMMISSION 47 CFR Part 73 [MB Docket No. 08-85; RM-11427, RM-11517, RM-11518, RM-11519; DA 11- 2059] Radio Broadcasting Services; Ehrenberg, First Mesa, Kachina Village, Wickenburg, and Williams, AZ, and Needles, CA AGENCY: Federal Communications Commission. ACTION: Proposed...

  2. William Wordsworth’s Danish Ghost and the Ballad that Never Was

    DEFF Research Database (Denmark)

    Jensen-Rix, Robert William

    2017-01-01

    ABSTRACT William Wordsworth’s “A Fragment,” later renamed as “The Danish Boy. A Fragment,” was first published in Lyrical Ballads (1800). It is a vignette of a ghost – a Danish boy – singing in the landscape. It is the aim of the article to examine the poem in a number of contexts that have...

  3. Attention Bias to Emotional Faces Varies by IQ and Anxiety in Williams Syndrome

    Science.gov (United States)

    McGrath, Lauren M.; Oates, Joyce M.; Dai, Yael G.; Dodd, Helen F.; Waxler, Jessica; Clements, Caitlin C.; Weill, Sydney; Hoffnagle, Alison; Anderson, Erin; MacRae, Rebecca; Mullett, Jennifer; McDougle, Christopher J.; Pober, Barbara R.; Smoller, Jordan W.

    2016-01-01

    Individuals with Williams syndrome (WS) often experience significant anxiety. A promising approach to anxiety intervention has emerged from cognitive studies of attention bias to threat. To investigate the utility of this intervention in WS, this study examined attention bias to happy and angry faces in individuals with WS (N = 46). Results showed…

  4. William Horsley: Music Master at Miss Black's Boarding-School for Young Ladies, 1828-1840

    Science.gov (United States)

    Woodall, Susan

    2009-01-01

    William Horsley (1775-1858) was active in London from the late 1790s. A founder member of the Philharmonic Society, Horsley was at the heart of the musical establishment, working as a composer, organist, commentator and teacher. His teaching career spanned over 50 years, during which time he took private pupils, trained choristers and organists…

  5. Using Picture Books to Provide Archetypes to Young Boys: Extending the Ideas of William Brozo

    Science.gov (United States)

    Zambo, Debby

    2007-01-01

    In his book "To Be a Boy, To Be a Reader: Engaging Teen and Preteen Boys in Active Literacy," William Brozo suggested that many adolescent boys have become mentally and academically detached from school. While Brozo acknowledges that a solution to these problems is multifaceted, he asserts that engaging boys in literature that makes use of…

  6. 75 FR 32743 - Action Affecting Export Privileges; Green Supply, Inc.; Robert Leland Green and William Robert...

    Science.gov (United States)

    2010-06-09

    ... C. Benefitting in any way from any transaction involving any item exported or to be exported from... DEPARTMENT OF COMMERCE Bureau of Industry and Security Action Affecting Export Privileges; Green Supply, Inc.; Robert Leland Green and William Robert Green; Order Denying Export Privileges In the Matter...

  7. Refuting the Evidentialist Challenge to Religion: A Critique Inspired by William James

    NARCIS (Netherlands)

    Grube, Dirk-Martin

    2003-01-01

    In this article, evidentialism is refuted by relying on William James’ article ‘The Will to Believe’. After an introduction into the notion of ‘evidentialism’ and James’ attack on it (section 1), I distinguish between two sorts of evidentialisms, truth-oriented evidentialism and quiescent

  8. William Blake’s Milton a Poem as a conversion narrative in the Behmenist tradition

    DEFF Research Database (Denmark)

    Jessen, Elisabeth Engell

    2014-01-01

    The term ‘conversion narrative’ lacks proper definition and can be understood more broadly than is often the case, underlining its fictive nature. I show this by reading William Blake’s Milton a Poem as a conversion narrative, exploring how Blake weaves a wider discourse of conversion around...

  9. Theory of Mind in Williams Syndrome Assessed Using a Nonverbal Task

    Science.gov (United States)

    Porter, Melanie A.; Coltheart, Max; Langdon, Robyn

    2008-01-01

    This study examined Theory of Mind in Williams syndrome (WS) and in normal chronological age-matched and mental age-matched control groups, using a picture sequencing task. This task assesses understanding of pretence, intention and false belief, while controlling for social-script knowledge and physical cause-and-effect reasoning. The task was…

  10. Stress in Families of Young Children with Down Syndrome, Williams Syndrome, and Smith-Magenis Syndrome.

    Science.gov (United States)

    Fidler, Deborah J.; Hodapp, Robert M.; Dykens, Elizabeth M.

    2000-01-01

    Compared stress levels in families of children with Down syndrome (DS), Williams syndrome (WS), or Smith-Magenis syndrome (SMS). Found that DS families experienced less Pessimism than others and less Parent and Family Problems than SMS families. Strongest predictors of Parent and Family Problems were maladaptive behavior in SMS, younger age in DS,…

  11. "A Marriage on the Rocks": An Unknown Letter by William H. Kilpatrick about His Project Method

    Science.gov (United States)

    Knoll, Michael

    2010-01-01

    William H. Kilpatrick is worldwide known as "Mr. Project Method." But the origin of his celebrated paper of 1918 has never been explored. The discovery of a hitherto unknown letter reveals that Kilpatrick was an educational entrepreneur who, without regard for language and tradition, adopted the term "project" and used it in a provocative new way…

  12. Spatial-Sequential and Spatial-Simultaneous Working Memory in Individuals with Williams Syndrome

    Science.gov (United States)

    Lanfranchi, Silvia; De Mori, Letizia; Mammarella, Irene C.; Carretti, Barbara; Vianello, Renzo

    2015-01-01

    The aim of the present study was to compare visuospatial working memory performance in 18 individuals with Williams syndrome (WS) and 18 typically developing (TD) children matched for nonverbal mental age. Two aspects were considered: task presentation format (i.e., spatial-sequential or spatial-simultaneous), and level of attentional control…

  13. Longitudinal Trajectories of Intellectual and Adaptive Functioning in Adolescents and Adults with Williams Syndrome

    Science.gov (United States)

    Fisher, M. H.; Lense, M. D.; Dykens, E. M.

    2016-01-01

    Background: Williams syndrome (WS) is associated with a distinct cognitive-behavioural phenotype including mild to moderate intellectual disability, visual-spatial deficits, hypersociability, inattention and anxiety. Researchers typically characterise samples of individuals with WS by their intellectual functioning and adaptive behaviour. Because…

  14. Anxiety in Williams Syndrome: The Role of Social Behaviour, Executive Functions and Change over Time

    Science.gov (United States)

    Ng-Cordell, Elise; Hanley, Mary; Kelly, Alyssa; Riby, Deborah M.

    2018-01-01

    Anxiety is a prevalent mental health issue for individuals with Williams syndrome (WS). Relatively little is known about the developmental course of anxiety, or how it links with core features of WS, namely social and executive functioning (EF). In this study, parent-reports of anxiety were compared across a 4-year period (N = 17), and links…

  15. The Formation of a Renaissance Nobleman: William Cecil, 2nd Earl of Salisbury 1591-1668.

    Science.gov (United States)

    Danushevskaya, Anna V.

    2002-01-01

    Focuses on the humanist ideal of nobility and humanist views about the type of education that would produce noblemen. Details the life and education of William Cecil, also known as Viscount Cranborne, as it pertains to humanist education culture established in the 16th and 17th centuries. (KDR)

  16. Nowhere man: The Countryside of Fred Williams after Western Desert painting

    Directory of Open Access Journals (Sweden)

    Darren Jorgenson

    2012-11-01

    Full Text Available Two monographs on Australian artist Fred Williams, published by Patrick McCaughey and James Mollison during the 1980s, have recently been joined by a third, Deborah Hart’s Fred Williams: Infinite Horizons (2011. While the first two argue that the artist’s work bridged a schism between Australian landscape painting and an internationalist contemporary art of the 1960s, the rise of Western Desert painting invites a new reading of his landscapes. Ron Radford’s Preface to Hart’s new monograph wants to reconcile the artist’s relationship to Western Desert painting with an anecdote about Clifford Possum’s visit to the Art Gallery of South Australia in 1984. Possum was enthusiastic about a painting by Williams, and Radford sees in this enthusiasm a reconciliation of Aboriginal and non-Aboriginal ways of seeing. Such different readings of Williams and his work, authored in different historical periods, reflect different moments in the unfolding of national anxieties that constitute the history of Australian art.

  17. Absolutism and Natural Law Argument: William O. Douglas on Freedom of Expression.

    Science.gov (United States)

    Rodgers, Raymond S.

    Noting that United States Supreme Court Justice William O. Douglas has often been characterized as an "absolutist" in terms of First Amendment policy, this paper argues that, in fact, Douglas's policy positions provided for less than absolute freedom to communicate. The paper then reveals, through an anlaysis of 18 of Douglas's opinions,…

  18. Cross Syndrome Comparison of Sleep Problems in Children with Down Syndrome and Williams Syndrome

    Science.gov (United States)

    Ashworth, Anna; Hill, Catherine M.; Karmiloff-Smith, Annette; Dimitriou, Dagmara

    2013-01-01

    Based on previous findings of frequent sleep problems in children with Down syndrome (DS) and Williams syndrome (WS), the present study aimed to expand our knowledge by using parent report and actigraphy to define sleep problems more precisely in these groups. Twenty-two school-aged children with DS, 24 with WS and 52 typically developing (TD)…

  19. Short-term effects of silviculture on breeding birds in William B. Bankhead National Forest

    Science.gov (United States)

    Jill M. Wick; Yong Wang; Callie Jo Schweitzer

    2013-01-01

    We evaluated the changes in the bird community in relation to six disturbance treatments in the William B. Bankhead National Forest, AL. The study design is randomized complete block with a factorial arrangement of three thinning levels [no thin, 11 m²/ha residual basal area (BA), and 17 m²/ha residual BA] and two burn treatments (burn and no burn),...

  20. Welche Zukunft für die Demokratie? Welche Demokratie für die Zukunft?

    Directory of Open Access Journals (Sweden)

    Alessandro Pinzani

    2010-01-01

    Full Text Available http://dx.doi.org/10.5007/1677-2954.2010v9n1p149 Otfried Höffes neuestes Buch zum Thema, Demokratie in der heutigen Welt“ – ein Thema, dem der Tübinger Sozialphilosoph schon die vorausgegangenen Bände Demokratie im Zeitalter der Globalisierung (1999 und Wirstschaftsbürger, Staatsbürger, Weltbürger (2004 gewidmet hatte – stellt einen wichtigen Versuch dar, die Frage der Zukunftsfähigkeit der Demokratie zu beantworten.

  1. Teistsugune vaade juhtide tasustamisele / Jack Welch, Suzy Welch ; intervjueerinud Stefan Eiselin

    Index Scriptorium Estoniae

    Welch, Jack

    2010-01-01

    USA juhtimisspetsialistide Jack ja Suzy Welchi hinnangul võib tippjuhtidele makstava palga ümber kerkinud poleemika üks võimalikke põhjuseid lisaks halvale kommunikatsioonile olla ka ideoloogiate kokkusobimatus

  2. The Microcosm within: An interview with William B. Miller, Jr., on the Extended Hologenome theory of evolution.

    Science.gov (United States)

    Hunt, Tam

    2015-01-01

    There is a singular unifying reality underlying every biologic interaction on our planet. In immunology, that which does not kill you makes you different. -William B. Miller, Jr. We are experiencing a revolution in our understanding of inner space on a par with our exponentially increasing understanding of outer space. In biology, we are learning that the genetic and epigenetic complexity within organisms is far deeper than suspected. This is a key theme in William B. Miller Jr.'s book, The Microcosm Within: Evolution and Extinction in the Hologenome. We are learning also that a focus on the human genome alone is misleading when it comes to who we really are as biological entities, and in terms of how we and other creatures have evolved. Rather than being defined by the human genome alone, we are instead defined by the "hologenome," the sum of the human genome and the far larger genetic endowment of the microbiome and symbiotic communities that reside within and around us. Miller is a medical doctor previously in private practice in Pennsylvania and Phoenix, Arizona. This book is his first foray into evolutionary theory. His book could have been titled "The Origin of Variation" because this is his primary focus. He accepts that natural selection plays a role in evolution, but he demotes this mechanism to a less important role than the Modern Synthesis suggests. His main gripe, however, concerns random variation. He argues that random variation is unable to explain the origin and evolution of biological forms that we see in the world around us and in the historical record. Miller suggests that, rather than random variation as the engine of novelty, there is a creative impulse at the heart of cellular life, and even at the level of the genetic aggregate, that generates novelty on a regular basis. I probe this assertion in the interview below. He also highlights the strong role of "exogenous genetic assault" in variation and in his immunological model of evolution.

  3. Variation in the Williams syndrome GTF2I gene and anxiety proneness interactively affect prefrontal cortical response to aversive stimuli.

    Science.gov (United States)

    Jabbi, M; Chen, Q; Turner, N; Kohn, P; White, M; Kippenhan, J S; Dickinson, D; Kolachana, B; Mattay, V; Weinberger, D R; Berman, K F

    2015-08-18

    Characterizing the molecular mechanisms underlying the heritability of complex behavioral traits such as human anxiety remains a challenging endeavor for behavioral neuroscience. Copy-number variation (CNV) in the general transcription factor gene, GTF2I, located in the 7q11.23 chromosomal region that is hemideleted in Williams syndrome and duplicated in the 7q11.23 duplication syndrome (Dup7), is associated with gene-dose-dependent anxiety in mouse models and in both Williams syndrome and Dup7. Because of this recent preclinical and clinical identification of a genetic influence on anxiety, we examined whether sequence variation in GTF2I, specifically the single-nucleotide polymorphism rs2527367, interacts with trait and state anxiety to collectively impact neural response to anxiety-laden social stimuli. Two hundred and sixty healthy adults completed the Tridimensional Personality Questionnaire Harm Avoidance (HA) subscale, a trait measure of anxiety proneness, and underwent functional magnetic resonance imaging (fMRI) while matching aversive (fearful or angry) facial identity. We found an interaction between GTF2I allelic variations and HA that affects brain response: in individuals homozygous for the major allele, there was no correlation between HA and whole-brain response to aversive cues, whereas in heterozygotes and individuals homozygous for the minor allele, there was a positive correlation between HA sub-scores and a selective dorsolateral prefrontal cortex (DLPFC) responsivity during the processing of aversive stimuli. These results demonstrate that sequence variation in the GTF2I gene influences the relationship between trait anxiety and brain response to aversive social cues in healthy individuals, supporting a role for this neurogenetic mechanism in anxiety.

  4. Conditions of persistent oil on beaches in Prince William Sound 26 years after the Exxon Valdez spill

    Science.gov (United States)

    Lindeberg, Mandy R.; Maselko, Jacek; Heintz, Ron A.; Fugate, Corey J.; Holland, Larry

    2018-01-01

    On March 24, 1989, the Exxon Valdez grounded on Bligh Reef in Prince William Sound, Alaska, spilling an estimated 10.8 million gallons of crude oil. Contrary to early projections, subsequent studies over several decades have shown subsurface oil persisting on impacted beaches. Here we present findings from a lingering oil survey conducted during the summer of 2015 at a small set of beaches in Prince William Sound known to have persistent subsurface Exxon Valdez oil. The objectives of the survey were to estimate how much oil remains at these sites, the oil composition, and oil retention rates compared to previous studies. Results from the survey found lingering oil was present at 8 of 9 sites that were revisited. Surveys revealed little evidence of change in oil area or mass over the last 14 years, nor has there been a change in the distribution of oiling intensities or their location on the beach. Detailed analysis of the oil indicated it has not weathered since 2001. Subsurface oils collected in 2015 have enriched concentrations of phenanthrenes and chrysenes relative to oil originating in the cargo hold indicating that buried oil has retained some toxic potential over the last two decades, but it is not currently bioavailable. Subsurface oil appears to be sequestered in sediments and protected from hydrological washing and low oxygen and nutrient levels inhibiting biodegradation. These findings are consistent with previous surveys and predictive geomorphic models suggesting the estimated 0.6% Exxon Valdez oil remaining is sequestered and not bioavailable unless disturbed and will likely persist in the environment on a decadal scale.

  5. 21 CFR Appendix A to Part 101 - Monier-Williams Procedure (With Modifications) for Sulfites in Food, Center for Food Safety and...

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Monier-Williams Procedure (With Modifications) for...-Williams Procedure (With Modifications) for Sulfites in Food, Center for Food Safety and Applied Nutrition...-Williams apparatus. Component identification is given in text. ER01JA93.363 Figure 2. Diagram of bubbler (F...

  6. Modeling and Simulation of the Visual Effects of Colored Filters

    Science.gov (United States)

    2015-02-01

    AFRL-RH-FS-TR-2015-0006 Modeling and Simulation of the Visual Effects of Colored Filters William R. Brockmeier Michael A. Guevara Thomas K. Kuyk...NUMBER FA8650-14-D-65190 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 0603231F 6. AUTHOR(S) William R. Brockmeier, Michael A. Guevara , Thomas K

  7. Determination of sulfur dioxide in grapes: comparison of the Monier-Williams method and two ion exclusion chromatographic methods.

    Science.gov (United States)

    Kim, H J; Conca, K R; Richardson, M J

    1990-01-01

    Results for determination of sulfur dioxide in grapes were compared by 3 methods: the modified Monier-Williams method, acid distillation/ion exclusion chromatography with electrochemical detection (AD/IEC-EC), and alkali extraction/ion exclusion chromatography with electrochemical detection (AE/IEC-EC). An unusual positive response was observed during the later stage of the Monier-Williams distillation of both control grapes and sulfited grapes. Development of volatile acidic compounds in parallel with this Monier-Williams response and darkening of sample was also observed by collection in an alkali trap and analysis using anion exclusion chromatography and photodiode array detection. No parallel increase in sulfite was observed by the more selective AD/IEC-EC method, which clearly demonstrated that the response observed during the later stage of the Monier-Williams method is a false positive, probably due to caramelization reaction products. Monier-Williams results for grapes containing ca 10 ppm sulfite were in reasonably good agreement with those by either the AD/IEC-EC or AE/IEC-EC methods, presumably because the false positive response in the Monier-Williams analysis compensated for the somewhat incomplete recovery of sulfite. The AE/IEC-EC method is recommended because it is rapid, sensitive, straightforward, and free from interference. Accurate results by Monier-Williams analysis could be obtained by limiting distillation to 60 min and correcting for recovery.

  8. Williams syndrome predisposes to vascular stiffness modified by antihypertensive use and copy number changes in NCF1.

    Science.gov (United States)

    Kozel, Beth A; Danback, Joshua R; Waxler, Jessica L; Knutsen, Russell H; de Las Fuentes, Lisa; Reusz, Gyorgy S; Kis, Eva; Bhatt, Ami B; Pober, Barbara R

    2014-01-01

    Williams syndrome is caused by the deletion of 26 to 28 genes, including elastin, on human chromosome 7. Elastin insufficiency leads to the cardiovascular hallmarks of this condition, namely focal stenosis and hypertension. Extrapolation from the Eln(+/-) mouse suggests that affected people may also have stiff vasculature, a risk factor for stroke, myocardial infarction, and cardiac death. NCF1, one of the variably deleted Williams genes, is a component of the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase complex and is involved in the generation of oxidative stress, making it an interesting candidate modifier for vascular stiffness. Using a case-control design, vascular stiffness was evaluated by pulse wave velocity in 77 Williams cases and matched controls. Cases had stiffer conducting vessels than controls (P<0.001), with increased stiffness observed in even the youngest children with Williams syndrome. Pulse wave velocity increased with age at comparable rates in cases and controls, and although the degree of vascular stiffness varied, it was seen in both hypertensive and normotensive Williams participants. Use of antihypertensive medication and extension of the Williams deletion to include NCF1 were associated with protection from vascular stiffness. These findings demonstrate that vascular stiffness is a primary vascular phenotype in Williams syndrome and that treatment with antihypertensives or agents inhibiting oxidative stress may be important in managing patients with this condition, potentially even those who are not overtly hypertensive.

  9. Report to the William and Flora Hewlett Foundation

    Energy Technology Data Exchange (ETDEWEB)

    Eisner, E.

    1978-12-01

    A biological model is presented for determining effects of an environmetal variable on a physiological variable. The effect of an environmental variable, temperature, on a physiological variable, oxygen consumption, was studied. (HLW) Measurements were made on oxygen consumption of mice following exposure to different temperatures. A graph is presented to show results. A model was developed to show: thermal regulation; ratio of change in heat production to change in body temperature; thermal capacity of the body; heat transfer coefficient of the fur; and volume of oxygen required to produce a unit of heat by metabolism. The relevance of the results to ecosystems is discussed.

  10. Liquidity Preference Theory: A Comparison of William Baumol's and ...

    African Journals Online (AJOL)

    Mrs Afam

    expenditures, availability of money substitutes and the number of non-bank financial institutions. Keynes [1936] ... of purchasing power that can be used to finance unanticipated expenditures, and (iii) the speculative .... that, inventory model of cash management implies that the amount of cash held in transaction balances is ...

  11. La haine à l’œuvre dans Carpenter’s Gothic (1999 de William Gaddis Cultivating Hatred in Carpenter’s Gothic (1999 by William Gaddis

    Directory of Open Access Journals (Sweden)

    Jacques Sohier

    2007-01-01

    Full Text Available In Carpenter’s Gothic, hatred is given pride of place. William Gaddis delineates a society in which hatred proliferates. Characters are caught in the turmoils of their hatred whether it derives from the Vietnam War or from fundamentalist movements, from their individualistic quest for social recognition or from self-aggrandizement. We mean to develop a typology derived from psychoanalysis and anthropology so as to take into account all the different facets hate has in the novel. We shall devote analyses to jealousy caused by hatred, then describe the primary hate that underpins all types of relationships as a preliminary to questioning the excess that fuels Gaddis’s writing. Lastly, by referring to the author’s non-fictional work we shall put forward the thesis that the voluble protagonist is to a large extent the author’s mouthpiece. McCandless’s vindictive disquisitions on the course of the world will be seen as the equivalent of a tragic mask through which William Gaddis gives vent to his melancholia and intense detestation of the ways of the world.

  12. Charles Dickens and Barnaby Rudge: The First Description of Williams Syndrome?

    Science.gov (United States)

    Eblovi, Darren; Clardy, Christopher

    2016-02-01

    Williams syndrome, a disorder caused by a genetic deletion and characterized by moderate intellectual disability with relatively strong language skills and a hypersocial personality, was first described in the medical literature in 1961. However, 120 years earlier, Charles Dickens wrote the novel Barnaby Rudge, which follows an "idiot" through London's Gordon Riots of 1780. We propose that Dickens based this character on a person he knew with Williams syndrome. Common features include an "elfin" face, decreased cognitive ability and dependence on a caretaker, strong language skills with emphatic and perseverative speech, anxiety, and an empathetic, overly trusting personality. In the novel, these traits lead the character Barnaby to be duped into actively participating in the riots, which nearly results in his hanging. This example of fiction providing a description of a disorder more detailed than that of medical journals more than a century later should encourage physicians to look to sources beyond traditional scientific articles for valuable clinical information. Copyright 2016, SLACK Incorporated.

  13. Mapping cultural resource sites for the Prince William Sound Graphical Resource Database

    International Nuclear Information System (INIS)

    Wooley, C. B.; O'Brien, D. K.; Hillman, S. O.

    1997-01-01

    A software package for mapping digital data 'layers' of environmentally and/or culturally sensitive areas such as seabird colonies, seal haulouts, and sea otter concentrations in Prince William Sound and adjoining areas of southern Alaska has been developed by the Alyeska Pipeline Service Company. The data is to be added to an environmental computer mapping database. More than 1,800 known and reported coastal cultural resource sites have been identified. The database is part of the Prince William Sound Tanker Oil Discharge Prevention and Contingency Plan. The mappable data layers can be used to plan and execute whatever site protection program may be necessary, thus enhancing effective cultural resource protection during an oil spill response. 22 refs., 4 figs

  14. Environmental recover in Prince William Sound and the Gulf of Alaska

    International Nuclear Information System (INIS)

    Clark, R.B.; Kingston, P.F.; Baker, J.M.

    1991-01-01

    This report is based on work commissioned by Exxon as part of a program of analyzing the ecosystem recovery process in Prince William Sound and the Gulf of Alaska following the oil spill of March 1989. Written by three distinguished scientists, it supplements a comprehensive study they and a fourth researcher prepared on the subject of Natural Recovery of Cold Water Marine Environments after an Oil Spill. This scientific review was presented at the 13th Arctic and Marine Oilspill Program Technical Seminar sponsored by the Canadian Government in Edmonton, Alberta, on June 6, 1990. As a followup to this study, the scientists spent two weeks in April 1990 gathering insight into the Prince William Sound and Gulf of Alaska environment as a whole and examining plant and animal life in the area. They compared their Alaska findings to their knowledge gained from studying the recovery process from other oil spills in cold waters of the world

  15. Os conceitos de cultura e comunicação em Raymond Williams

    OpenAIRE

    Cunha, Raquel Cantarelli Vieira da

    2011-01-01

    O trabalho analisa os conceitos de cultura e de comunicação em Raymond Williams, na tentativa de compreender as relações que se estabelecem entre o campo da Comunicação e os Estudos Culturais. Para tanto, é apresentado um breve panorama do campo da Comunicação e dos Estudos Culturais britânicos e também passa em revista os conceitos de cultura nas ciências sociais. São analisadas algumas das principais contribuições do pensamento de Williams – como sua proposição de Sistemas de Comunicação – ...

  16. William Ospina y la búsqueda de la franja amarilla

    Directory of Open Access Journals (Sweden)

    Víctor Valero Bernal

    2016-12-01

    Full Text Available El objetivo de este artículo es el de analizar el ensayo «Lo que le falta a Colombia» del escritor William Ospina. En este ensayo Ospina profundiza en los principales problemas sociales y políticos que Colombia atravesaba a finales del s. XX así como en las posibles soluciones que podrían adoptarse. Los planteamientos que emplea el escritor colombiano pueden relacionarse con una gran variedad de conceptos propios del ámbito de la política y la sociología. A lo largo de este trabajo mostraremos las analogías existentes entre el análisis de William Ospina y las ideas de pensadores tan alejados en el tiempo como Thomas Hobbes, Rousseau, John Rawls o Charles Tilly.

  17. Affek van toe tot nou: Die erfenis van Herder, Schleiermacher en William James

    Directory of Open Access Journals (Sweden)

    Yolanda Dreyer

    2014-08-01

    Full Text Available Affect then and now: The heritage of Herder, Schleiermacher and William James. The heritage of Johann Gottfried von Herder (1744�1803, Friedrich Schleiermacher (1768�1834 and William James (1842�1910 is of significance for practical theology. In present-day pastoral care, affect, emotion, feeling and experience are explored by means of, amongst others, narrative theories. In his aesthetics, Herder linked music and literature. Schleiermacher, in his aesthetics, linked his theology of feeling with biography as narrative. Narrativity is central to present-day are theories and praxis in pastoral care. The variety of forms of affect, namely emotion, experience, feeling and mood, has been explored by present-day psychology and psychiatry. These insights can enrich narrative pastoral theories and praxis.

  18. Bringing inorganic chemistry to life with inspiration from R. J. P. Williams.

    Science.gov (United States)

    Hill, H Allen O; Sadler, Peter J

    2016-03-01

    Our appreciation of the scholarly ideas and thinking of Bob Williams is illustrated here by a few of the areas in which he inspired us. His journey to bring inorganic chemistry to life began with an early interest in analytical chemistry, rationalising the relative stabilities of metal coordination complexes (The Irving-Williams Series), and elucidating the organometallic redox chemistry of vitamin B12. He (and Vallee) recognised that metal ions are in energised (entatic) states in proteins and enzymes, which themselves are dynamic structures of rods and springs. He played a key role in helping Rosenberg to pave the road toward the clinic for the anticancer drug cisplatin. He believed that evolution is not just dependent on DNA, but also on the metallome. Organisms and the environment are one system: does DNA code directly for all the essential elements of life?

  19. Reevaluation of Monier-Williams method for determining sulfite in food

    Energy Technology Data Exchange (ETDEWEB)

    Warner, C.R.; Daniels, D.H.; Joe, F.L. Jr.; Fazio, T.

    The Monier-Williams distillation procedure has a long history of successful use for determining sulfite in fruit products and wine; however, a systematic evaluation of its accuracy and precision with other food matrices has not been undertaken. The authors found that Monier-Williams distillation yielded >90% recovery of sulfite added to foods such as table grapes, hominy, dried mangoes, and lemon juice. Less than 85% recovery was obtained with broccoli, soda crackers, cheese-peanut butter crackers, mushrooms, and potato chips. These results may, in fact, accurately reflect the residual levels of sulfite if a portion of the sulfite undergoes irreversible reaction with some food components. Analysis of commercial food products gave sulfite levels as 25 ppm in cream sherry.

  20. William Shakespeare’ın Hamlet Yapıtının A. J. Greimas’ın Eyleyensel Örnekçesine Göre Çözümlenmesi

    OpenAIRE

    Baloğlu, Uğur

    2013-01-01

    The analysis of semiology has been previously used in only linguistic analysis but in time it was started to be used to analyse in different ares such as cinema, music, advertising poster etc. In this article, Algirdas Julien Greimas’s the actantial model and narrative curriculum will be discussed who was inspired by narrative science of Vladimir Propp in respect to the structuralism and making up his own analysis method. Considering these facts, William Shakespeare’s play...

  1. Estrutura e significado em "Uma rosa para Emily", de William Faulkner

    Directory of Open Access Journals (Sweden)

    Carlos Daghlian

    2004-01-01

    Full Text Available Trata-se de uma análise do consagrado conto "Uma Rosa para Emily", de William Faulkner, voltada para alguns dos principais aspectos de sua estrutura. Após considerarmos o enredo, discutimos a construção das personagens, com destaque para a protagonista, fazendo um levantamento e comentários sobre possíveis fontes de inspiração, destacando, entre outras, aspectos da biografia da poeta Emily Dickinson, a ficção e a poesia de E. A. Poe, romances de Charles Dickens e Henry James, o conto de Sherwood Anderson e a poesia de William Blake, Emily Dickinson, Robert Browning e John Crowe Ransom, acrescentando paralelos com o conto "Bartleby, o escrivão", de Herman Melville. Analisamos, então, o foco narrativo, os símbolos e o significado, ressaltando aqui o desenvolvimento temático da narrativa.This is an analysis of the well-known short story "A Rose for Emily," by William Faulkner, concentrating on some of the main aspects of its structure. A consideration of the plot is followed by a discussion of characterization, with emphasis on the protagonist, by means of a survey and comments on possible sources of inspiration including, among others, aspects of Emily Dickinson's biography, E. A. Poe's fiction and poetry, novels by Charles Dickens and Henry James, Sherwood Anderson's short stories, and the poetry of William Blake, Emily Dickinson, Robert Browning, and John Crowe Ransom, in addition to Herman Melville's short story "Bartleby, the Scrivener." The narrative focus, symbolism and meaning, stressing the thematic development of the narrative, are then analyzed.

  2. Ethnicity, Expertise and Authority: the cases of Lewis Howard Latimer, William Preece and John Tyndall

    OpenAIRE

    Gooday, G

    2015-01-01

    To become an authority figure in late nineteenth century electricity, neither a higher education nor mainstream ethnic identity were necessary. This paper examines three diverse examples of Anglo-American experts/authorities who succeeded during their lifetime in at least some level of major recognition by performing publicly in the role of expert or authority figure: the African American Lewis Howard Latimer; the Welshman William Preece, and the Irishman John Tyndall. In the USA the outstand...

  3. Early artificial ventilation: the mystery of "Truehead of Galveston"--was he Dr Charles William Trueheart?

    Science.gov (United States)

    Trubuhovich, Ronald V

    2008-12-01

    It seems strange that the medical literature from the United States has only a single original source of reference for a device (from circa 1870) for artificial ventilation in neonatal resuscitation. The invention is attributed to "Dr Truehead of Galveston, Texas". I argue that this mystery arises from two separate misspellings of the inventor's name, and propose that the correct name is Dr Charles William Trueheart (1837-1914), also of Galveston.

  4. Women and Wilderness : The Topology of Intimacy in Terry Tempest Williams' Refuge

    OpenAIRE

    Yuki, Masami

    1996-01-01

    In terms of politics, the arid landscape of Utah has received a twofold dismissal as wilderness: it is labelled as "a blank spot on the map" and therefore considered the legitimate "downwind" area of radioactive fallout from Nevada Test Site on the one hand; and on the other, Utah has been marginalized because of its major population, the Mormons. Terry Tempest Williams, one of the major western American nature writers and also a Mormon, tries to rebuild such a rationalistic perspective from ...

  5. Habit Reversal Therapy for Body-Focused Repetitive Behaviors in Williams Syndrome: A Case Study

    OpenAIRE

    Conelea, Christine A.; Klein-Tasman, Bonita P.

    2013-01-01

    Williams syndrome (WS) is genetic neurodevelopmental disorder with a well-characterized cognitive and behavioral phenotype. Research has consistently demonstrated high rates of psychopathology in this population; however, little research has examined the use of empirically-supported psychosocial interventions in those with WS. The current case study reports on the use of Habit Reversal Therapy (HRT) to treat multiple body-focused repetitive behaviors in a child with WS. Although HRT is a well...

  6. 3D PATTERN OF BRAIN ABNORMALITIES IN WILLIAMS SYNDROME VISUALIZED USING TENSOR-BASED MORPHOMETRY

    OpenAIRE

    Chiang, Ming-Chang; Reiss, Allan L.; Lee, Agatha D.; Bellugi, Ursula; Galaburda, Albert M.; Korenberg, Julie R.; Mills, Debra L.; Toga, Arthur W.; Thompson, Paul M.

    2007-01-01

    Williams syndrome (WS) is a neurodevelopmental disorder associated with deletion of ~20 contiguous genes in chromosome band 7q11.23. Individuals with WS exhibit mild to moderate mental retardation, but are relatively more proficient in specific language and musical abilities. We used tensor-based morphometry (TBM) to visualize the complex pattern of gray/white matter reductions in WS, based on fluid registration of structural brain images.

  7. ANALYSIS OF RAIN BY WILLIAM SOMERSET MAUGHAM IN TERMS OF POST-COLONIAL TERMS

    OpenAIRE

    Şaban KÖKTÜRK; Mehmet Cem ODACIOĞLU; Müge UYSAL

    2015-01-01

    This study dealt with the analysis of a short story, Rain by William Somerset Maugham in terms of post-colonial terms or elements. Before the analysis, the writer of the book was introduced and then the plot was explained so as to make readers familiar with the short story. In the analysis section, post-colonial elements or related terms such as missionary, colonial authority, the state of being subaltern, Manichean allegory, mimicry, ambivalence, surveillance, imperial hegemony, hybridity, e...

  8. The Dance of the Dead Rhino: William Kentridge’s Magic Flute

    OpenAIRE

    Guarracino, Serena

    2010-01-01

    The article offers a reading of the staging of The Magic Flute by visual artist William Kentridge, focusing on his introduction of the rhino in the visual landscape of the opera as symbol for the silenced subject of violence. Operatic tradition has always been concerned with the staging of death, in particular with the death of its female protagonists, and recent scholarship has highlighted the complicity of the genre with the ideology of Western patriarchy and colonial violence. In this ligh...

  9. The narrative profile in Williams syndrome: There is more to storytelling than just telling a story

    OpenAIRE

    Gonçalves, Óscar F.; Pinheiro, Ana P.; Sampaio, Adriana; Sousa, Nuno; Férnandez, Montse

    2010-01-01

    Williams Syndrome (WS) is a neurodevelopmental disorder that is characterized by a distinctive neurocognitive and behavioural phenotype, where relative cognitive strengths (e.g., language, narrative production, and face processing) coexist with severe deficits in other cognitive domains (e.g., visual-spatial processing). By using a new scoring system, this study aimed to explore structural (coherence), process (complexity) and content (multiplicity) aspects of fictional narrative production i...

  10. A rare case of discrete aortic coarctation in Williams-Beuren syndrome. Diagnostic and therapeutic considerations

    OpenAIRE

    Savina Mannarino; Eitan Keizman; Michele Pasotti; Alessia Claudia Codazzi; Elisabetta De Sando; Alessandro Giamberti

    2015-01-01

    Williams-Beuren syndrome (WBS) is a genetic disorder caused by elastin gene deletions, and is characterized by cardiovascular malformations, primarily including supravalvular aortic stenosis and peripheral pulmonary stenosis. We report a case of a neonate who developed severe discrete aortic coarctation, underwent multiple surgical interventions, and was subsequently diagnosed with WBS. Severe discrete aortic coarctation is a rare event in WBS newborns. An abnormally thick aortic wall is pres...

  11. William Wordsworth’s Danish Ghost and the Ballad that Never Was

    DEFF Research Database (Denmark)

    Jensen-Rix, Robert William

    2017-01-01

    William Wordsworth’s “A Fragment,” later renamed as “The Danish Boy. A Fragment,” was first published in Lyrical Ballads (1800). It is a vignette of a ghost – a Danish boy – singing in the landscape. It is the aim of the article to examine the poem in a number of contexts that have not previously...

  12. Between America and the Borders: William Johnstone’s Landscape Painting

    Directory of Open Access Journals (Sweden)

    Beth Williamson

    2017-05-01

    Full Text Available Scottish artist William Johnstone lived and worked in America for periods in the 1920s and 1940s, encountering a very different landscape to that he had grown up with in the Scottish Borders. This article investigates how Johnstone’s landscape paintings might be understood firstly as abstracted from nature and the Scottish landscape to which he felt so connected, and secondly in dialogue with the American landscape and culture he experienced during his visits.

  13. Environmental Impact Statement. Disposal and Reuse of Williams Air Force Base, Arizona.

    Science.gov (United States)

    1994-06-01

    vegetation consists of creosote bush, cacti, and native shrubs and grasses. Access to the Williams AFB area is provided by several highways which serve the...and in situ bioremediation ; remediation below health-protective levels is expected to take three years. For groundwater, the preferred alternative...dominated by creosote bush (Larrea tridentata) and other desert shrubs adapted to low rainfall conditions. Cacti and succulents typical of the Sonoran

  14. William Ockhamin trinitaarinen teologia sen myöhäiskeskiaikaisessa kontekstissa

    OpenAIRE

    Posti, Mikko

    2012-01-01

    Tässä tutkimuksessa esitellään ja analysoidaan William Ockhamin käsitystä kolminaisuusopista. Tutkimuksen metodina on systemaattinen analyysi. Huomiota kiinnitetään etenkin kolminaisuusoppiin liittyviin metafyysisiin ja loogisiin kysymyksiin, joita myöhäiskeskiajalla pidettiin keskeisinä. Tutkielman päälähteinä on käytetty Ockhamin Sentenssikommentaaria ja Quodlibeta septem -teosta. Ockhamin trinitaarista teologiaa voidaan luontevasti tarkastella osana 1300-luvun latinankielistä filosofi...

  15. Environmental Sensitivity Index (ESI) Atlas: Prince William Sound, Alaska, Volumes 1 and 2, geographic information systems data (NODC Accession 0019218)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set comprises the Environmental Sensitivity Index (ESI) data for Prince William Sound, Alaska. ESI data characterize estuarine environments and wildlife by...

  16. Two Schemes of Intellectual Development: A Comparison of Development as Defined by William Perry and Jean Piaget.

    Science.gov (United States)

    Perry, Bruce; And Others

    1986-01-01

    A comparison of the theories of Jean Piaget and William Perry (using individual interviews with college students) shows that the two theories outline different and independent processes for assessing intellectual development. (JN)

  17. 78 FR 77508 - Duke Energy Carolinas, LLC; William States Lee III Nuclear Station, Units 1 and 2; Combined...

    Science.gov (United States)

    2013-12-23

    ... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION Duke Energy Carolinas, LLC; William States Lee III Nuclear Station, Units 1 and 2; Combined Licenses Application Review AGENCY: Nuclear Regulatory Commission. ACTION: Final environmental impact...

  18. Environmental Footprint Analysis of Steam Enhanced Extraction Remedy: Former Williams Air Force Base, Site ST012 Mesa, AZ

    Science.gov (United States)

    This green remediation (GR) study quantifies environmental footprint for an In-Situ Thermal Treatment (ISTT) remedy using Steam Enhanced Extraction (SEE) for Site ST012 located on the Former Williams Air Force Base (AFB) in Mesa, Arizona.

  19. Wilsonian visions of a new world order in concrete terms : the case of William C. Bullitt / Alexander Sedlmaier

    Index Scriptorium Estoniae

    Sedlmaier, Alexander

    2003-01-01

    President Wilsoni internatsionalismi ideede pooldajast, vasakpoolse poliitika kriitikust pärast I maailmasõda Ameerika - Saksamaa suhete taustal, ajakirjanikust ja diplomaadist William C. Bullitt'ist (1891-1967)

  20. Simulasi Perdagangan Saham PT Tambang Batubara Bukit Asam, Tbk. dengan Macd dan Williams % Range

    Directory of Open Access Journals (Sweden)

    Benny Benny

    2010-11-01

    Full Text Available Moving Average Convergence Divergence (MACD is a momentum indicator to determine the indication of the trend reversal point. Williams% Range is also a momentum indicator that can provide when reversal trend will occur. This analysis will use the data movement of stock prices for PT Tambang Coal Bukit Asam Tbk. (PTBA. PTBA stock prices are influenced by fundamental conditions such as limited supply of fuel which is rumored and coal is the main alternative fuels other than oil. Study period was 241 trade days. Data are analyzed in several periods and then fitted with the MACD indicator and Williams % R, then simulate the trade during the period of research studies to determine the level of trading profits or losses based on the combination of both these technical indicators. The conclusion of this analysis, the MACD is an indicator that is considered slow (lagging in giving an indication of weakness, but in reverse the MACD is considered to provide an accurate indication of where the indication given is rarely wrong. Williams% R is an rapid indicator in anticipation of a reversal trend, but these indicators often give a false indication since this indicator is quite sensitive to the movement of stock prices goings go up or down. 

  1. Shoreline oiling conditions in Prince William Sound following the Exxon Valdez oil spill

    International Nuclear Information System (INIS)

    Neff, J.M.; Owens, E.H.; Stoker, S.W.; McCormick, D.M.

    1995-01-01

    Following the Exxon Valdez oil spill of March 24, 1989, in Prince William Sound, Alaska, Exxon conducted comprehensive, systematic shoreline surveys in cooperation with federal and state authorities to obtain information on the distribution and magnitude of shoreline oiling and to identify natural and cultural resources requiring special protection. Similar joint surveys were performed during the springs of 1990, 1991, and 1992 on all Prince william Sound and Gulf of Alaska shorelines that were suspected of having remnants of weathered oil and that would benefit from further cleanup. In the springs of 1990, 1991, and 1992, isolated pockets of subsurface oil were found, chiefly in small scattered zones in coarse cobble/boulder sediments in the upper intertidal or supratidal zones. In 1991, about one-third of the subdivisions in Prince William Sound with surface oil also contained some subsurface oil. The areal extent of this subsurface oil declined by nearly 70% between 1991 and 1992, from about 37,000 m 2 to about 12,000 m 2 . Moreover, where subsurface oil remained in 1992, it was present in lesser amounts. Rates of oil removal were greatest on coastal sections treated early in the spring and summer of 1989. Where shoreline treatment was delayed, the subsequent rate of removal of oil from the shore by natural processes was slower. 27 refs., 10 figs., 3 tabs

  2. Humdrum Tasks of the Salaried Men: Edwin Williams, a London County Council Architect at War

    Directory of Open Access Journals (Sweden)

    Nick Beech

    2015-12-01

    Full Text Available Working at the London County Council Architects’ Department through the 1930s to 1950s, and known (if at all as a member of the design team for the Royal Festival Hall, Edwin Williams is usually presented as a regressive figure, his design work marked by his Beaux Arts training. Using archival evidence and histories of the construction industry, this paper sets out Williams’s role in the organisation of rescue and recovery services in London during the Second World War. The paper argues that through his development of training schools and curricula for Rescue Service personnel, Williams played a key role in the formation of a skilled, mechanised, modern demolition industry. Operating complex emergency projects under extreme conditions, the same contractors and building operatives trained in Williams’s programme were later responsible for the clearance of bomb damaged sites and slums. This paper suggests that certain developments in modern architecture can be considered contingent upon practices of the demolition industry as developed by Williams. By concentrating on the ‘organisation’ and ‘progress’ of production that architects engaged with during the Second World War and after, new configurations of continuity and change emerge in which the ‘humdrum tasks’ of ‘salaried men’ appear crucial.

  3. Rencontre Nicolae Grigorescu – William Ritter. Perspectives des historiens de l’art

    Directory of Open Access Journals (Sweden)

    Ioana Vlasiu

    2013-12-01

    Full Text Available The art historians G. Oprescu (1881–1969 and Remus Niculescu (1927–2005 are those who studied closely the life and work of Nicolae Grigorescu (1838–1907, the most famous Romanian painter in the XIXth c., who left the Ecole des beaux-arts in Paris for the free school of Barbizon. This paper examines their positioning toward Nicolae Grigorescu’s relationship with the Swiss art critic William Ritter and raises question of subjectivity of interpretation. G. Oprescu’s view, who was also the publisher of William Ritter’s letters to the Romanian painter, is an excessively and incomprehensibly negative one. I will use also some inedited manuscript marginal notes of G. Oprescu on Ritter’s letters. Remus Niculescu avoids any comment on G. Oprescu’s opinions and examines rigorously from an art-historical perspective the texts written by William Ritter on Nicolae Grigorescu’s painting, published in different foreign art journals. Between focusing obsessively on the personal relationship of the two friends and ignoring them totally I will try to argue another view on the meeting Grigorescu-Ritter.

  4. Effectiveness of commercial microbial products in enhancing oil degradation in Prince William Sound field plots

    International Nuclear Information System (INIS)

    Venosa, A.D.; Haines, J.R.; Allen, D.M.

    1991-01-01

    In the spring of 1990, previously reported laboratory experiments were conducted on 10 commercial microbial products to test for enhanced biodegradation of weathered crude oil from the Exxon Valdez oil spill. The laboratory tests measured the rate and extent of oil degradation in closed flasks. Weathered oil from the beaches in Alaska and seawater from Prince William Sound were used in the tests. Two of the 10 products were found to provide significantly greater alkane degradation than flasks supplemented with mineral nutrients alone. These two products were selected for further testing on a beach in Prince William Sound. A randomized complete block experiment was designed to compare the effectiveness of these two products in enhancing oil degradation compared to simple fertilizer alone. Four small plots consisting of a no nutrient control, a mineral nutrient plot, and two plots receiving mineral nutrients plus the two products, were laid out on a contaminated beach. These four plots comprised a 'block' of treatments, and this block was replicated four times on the same beach. Triplicate samples of beach sediment were collected at four equally spaced time intervals and analyzed for oil residue weight and alkane hydrocarbon profile changes with time. The objective was to determine if either of the two commercial microbiological products was able to enhance bioremediation of an oil-contaminated beach in Prince William Sound to an extent greater than that achievable by simple fertilizer application. Results indicated no significant differences among the four treatments in the 27-day period of the experiment

  5. The pedagogical thought of William James: tactful teacher and moral education

    Directory of Open Access Journals (Sweden)

    Bianca Thoilliez

    2013-12-01

    Full Text Available The article seeks to present the philosophy of education that is at the very heart of William James’s legacy. It is argued that along with the rise of interest in the field of education towards classic American pragmatism, the study of William James has suffered from a lack of attention. After giving an accurate overview of the themes under debate in those few works which have addressed James’s thought from a pedagogical perspective, the article progresses on discussing some other educational themes which have gone unnoticed. More precisely, first, the inspiration offered by the image of the «tactful teacher» and, second, the philosophy of moral education that is part of James’s works on psychology. Both themes account for the pedagogical potential that continues to be hidden in the work of this philosopher. Received: 23/06/2013 / Accepted: 21/07/2013How to reference this articleThoilliez, B. (2013. El pensamiento pedagógico de William James: el tactful teacher y la educación moral. Foro de Educación, 11(15, pp. 83-102. doi: http://dx.doi.org/10.14516/fde.2013.011.015.004

  6. Seasonal variation of zooplankton abundance and community structure in Prince William Sound, Alaska, 2009-2016

    Science.gov (United States)

    McKinstry, Caitlin A. E.; Campbell, Robert W.

    2018-01-01

    Large calanoid copepods and other zooplankters comprise the prey field for ecologically and economically important predators such as juvenile pink salmon, herring, and seabirds in Prince William Sound (PWS).​ From 2009-2016, the Gulf Watch Alaska program collected zooplankton 5-10 times each year at 12 stations in PWS to establish annual patterns. Surveys collected 188 species of zooplankton with Oithona similis, Limacina helicina, Pseudocalanus spp., and Acartia longiremis as the most common species present in 519 samples. Generalized additive models assessed seasonal abundance and showed peak abundance in July (mean: 9826 no. m-3 [95% CI: 7990-12,084]) and lowest abundance in January (503 no. m-3 [373 to 678]). Significantly higher zooplankton abundance occurred in 2010 (542 no. m-3 ± 55 SE) and lowest in 2013 (149 no. m-3 ± 13). The species composition of communities, determined via hierarchical cluster analysis and indicator species analysis, produced six distinct communities based on season and location. The winter community, characterized by warm-water indicator species including Mesocalanus tenuicornis, Calanus pacificus, and Corycaeus anglicus, diverged into four communities throughout the spring and summer. The first spring community, characterized by copepods with affinities for lower salinities, occurred sound-wide. The second spring community, comprised of planktonic larvae, appeared sporadically in PWS bays in 2011-2013. Spring and summer open water stations were defined by the presence of large calanoid copepods. A summer community including the most abundant taxa was common in 2010 and 2011, absent in 2013, then sporadically appeared in 2014 and 2015 suggesting interannual variability of zooplankton assemblages. The zooplankton community shifted to a uniform assemblage characterized by cnidarians in the early autumn. Community assemblages showed significant correlations to a set of environmental variables including SST, mixed layer depth

  7. Arterial Hypertension in a Child with Williams-Beuren Syndrome (7q11.23 Chromosomal Deletion

    Directory of Open Access Journals (Sweden)

    Cristina de Sylos

    2002-08-01

    Full Text Available We report the case of a 7-year-old male child diagnosed with Williams-Beuren syndrome and arterial hypertension refractory to clinical treatment. The diagnosis was confirmed by genetic study. Narrowing of the descending aorta and stenosis of the renal arteries were also diagnosed. Systemic vascular alterations caused by deletion of the elastin gene may occur early in individuals with Williams-Beuren syndrome, leading to the clinical manifestation of systemic arterial hypertension refractory to drug treatment.

  8. "Normality of Residuals Is a Continuous Variable, and Does Seem to Influence the Trustworthiness of Confidence Intervals: A Response to, and Appreciation of, Williams, Grajales, and Kurkiewicz (2013"

    Directory of Open Access Journals (Sweden)

    Jason W. Osborne

    2013-09-01

    Full Text Available Osborne and Waters (2002 focused on checking some of the assumptions of multiple linear.regression. In a critique of that paper, Williams, Grajales, and Kurkiewicz correctly clarify that.regression models estimated using ordinary least squares require the assumption of normally.distributed errors, but not the assumption of normally distributed response or predictor variables..They go on to discuss estimate bias and provide a helpful summary of the assumptions of multiple.regression when using ordinary least squares. While we were not as precise as we could have been.when discussing assumptions of normality, the critical issue of the 2002 paper remains -' researchers.often do not check on or report on the assumptions of their statistical methods. This response.expands on the points made by Williams, advocates a thorough examination of data prior to.reporting results, and provides an example of how incremental improvements in meeting the.assumption of normality of residuals incrementally improves the accuracy of confidence intervals.

  9. Reassessment of the hydrocarbons in Prince William Sound and the Gulf of Alaska : identifying the source using partial least squares

    International Nuclear Information System (INIS)

    Mudge, S.M.

    2001-01-01

    Since the Exxon Valdez oil spill in Prince William Sound, Alaska there has been much discussion regarding the clean-up and long term fate of the oil. There has also been debate regarding the origin of the background hydrocarbons present within Prince William Sound (PWS) and the Gulf of Alaska (GoA). There is evidence that background (pre-spill) hydrocarbons may come from either nearby coal deposits or from natural oil seeps and eroding source rocks in the region. This paper presented a study in which the multivariate statistical methodology of the Partial Least Squares (PLS) was used to reassess the percentage contribution of coal, seep oil, shales and rivers to the hydrocarbon loading in the GoA. Data was provided by researchers at the National Ocean and Atmospheric Administration (NOAA) and the Bowdoin College, for Exxon. The data was analysed using selected sites as sources in order to develop signatures. The signatures were based on 40 and 136 compounds respectively, including the polyaromatic hydrocarbon (PAH) and terpane biomarkers from the Exxon data. The key components describing the sources were fitted to the data for other sites around the GoA to determine the proportion of the variability described by each source. The large complex datasets can be used to develop complex fingerprints for sources rather than using relatively simplistic ratios between selected compounds. The results indicate that 30 per cent of the signature is common between each source and that the small PAHs are the best diagnostic compounds in the model for the oil signature and the large PAHs are good for coal. Naphthalene, methyl and dimethyl naphthalene are the best markers for the seep oil signature. For the pre-spill background, coals and shales are best defined by the larger PAHs such as perylene and benzo(ghi)perylene. In general, the average partitioning between the two sources across all the sampling sites within the region indicated that 53 per cent is attributable to the

  10. Quantitative Assessment of Current Risks to Harlequin Ducks in Prince William Sound, Alaska, from the Exxon Valdez Oil Spill

    Science.gov (United States)

    Harwell, Mark A.; Gentile, John H.; Parker, Keith R.; Murphy, Stephen M.; Day, Robert H.; Bence, A. Edward; Neff, Jerry M.; Wiens, John A.

    2012-01-01

    Harlequin Ducks (Histrionicus histrionicus) were adversely affected by the Exxon Valdez oil spill (EVOS) in Prince William Sound (PWS), Alaska, and some have suggested effects continue two decades later. We present an ecological risk assessment evaluating quantitatively whether PWS seaducks continue to be at-risk from polycyclic aromatic hydrocarbons (PAHs) in residual Exxon Valdez oil. Potential pathways for PAH exposures are identified for initially oiled and never-oiled reference sites. Some potential pathways are implausible (e.g., a seaduck excavating subsurface oil residues), whereas other pathways warrant quantification. We used data on PAH concentrations in PWS prey species, sediments, and seawater collected during 2001–2008 to develop a stochastic individual-based model projecting assimilated doses to seaducks. We simulated exposures to 500,000 individuals in each of eight age/gender classes, capturing the variability within a population of seaducks living in PWS. Doses to the maximum-exposed individuals are ∼400–4,000 times lower than chronic toxicity reference values established using USEPA protocols for seaducks. These exposures are so low that no individual-level effects are plausible, even within a simulated population that is orders-of-magnitude larger than exists in PWS. We conclude that toxicological risks to PWS seaducks from residual Exxon Valdez oil two decades later are essentially non-existent. PMID:23723680

  11. William Hogarth

    DEFF Research Database (Denmark)

    Vibolt Knudsen, Vibeke

    Bogen følger nogle hovedspor, som indkredser mangfoldigheden i Hogarths grafiske værk. Overordnet set er målet at åbne op for hans ekstremt detaljerede og informative billeder gennem en række nærlæsninger af de vigtigste af hans serier og historier, hvor kunstnerens narrative greb undersøges, del...

  12. Williams Syndrome

    Science.gov (United States)

    ... and use good grammar. More than 50% of children with WS have attention deficit disorders (ADD or ADHD), and ... in cognitive development or learning difficulties, a distinctive facial appearance, and a unique ...

  13. El concepto de neurosis de William Cullen como revolución científica

    OpenAIRE

    José Luis Rivera Salazar; Jacobo Axel Murillo Villa; Miguel Ángel Sierra Rubio

    2007-01-01

    El concepto de neurosis ha sido problemático desde su creación en 1769. El ob-jetivo de este ensayo es mostrar la introducción del concepto de neurosis de William Cullen para revalorarlo como un concepto fundamental de la psicología clínica actual. El problema que se aborda es si hay una revolución científica en la medicina del siglo XVIII con la introducción de tal concepto. Los autores suponen que posiblemente sea así, para lo cual utilizan un método epistemológico, basado...

  14. William of Ockham y el problema del conocimiento introspectivo de nuestras intuiciones en sus primeros escritos

    OpenAIRE

    Deni Gamboa, Lydia

    2016-01-01

    En la filosofía de la mente contemporánea, la idea de que tenemos un acceso epistémico privilegiado a nuestros propios estados mentales ha sido considerada incompatible con el externalismo de los contenidos mentales. William of Ockham, en el siglo XIV, también parece haber observado que no podemos tener un acceso epistémico privilegiado al contenido de nuestros estados mentales – particularmente, de nuestras intuiciones, si tal contenido depende de algún factor externo y no sólo de nuestros e...

  15. William Edward Gallie (1882-1959): father of the Gallie wiring technique for atlantoaxial arthrodesis.

    Science.gov (United States)

    Dossani, Rimal Hanif; Shaughnessy, John; Kalakoti, Piyush; Nanda, Anil

    2018-03-01

    William Edward Gallie (1882-1959) was a Canadian general surgeon with special expertise in orthopedic surgery. His experience with surgical management of cervical spine subluxation led him to invent a method of cervical wiring of the atlas to the axis. His method of C1-2 wiring has since been modified, but it still remains one of the three most commonly taught wiring techniques in neurosurgical training programs. Gallie is also hailed for instituting the first surgical training program in Canada, a curriculum his pupils memorialized as the "Gallie course" in surgery. In this historical vignette, the authors describe Gallie's life and depict his contributions to surgery.

  16. Williams AFB, Chandler, Arizona. Revised Uniform Summary of Surface Weather Observations (RUSSWO)

    Science.gov (United States)

    1975-07-16

    HOURLY OBSERVATIONS) 23104 WILLIAMS AFB ARIZONA/CHANDLER 42-74 NOV STlAT ION STATION AME{ TRDEMNTH ALL WEATHER 0900-1100 ClASS MOVIS (L ST.) CONDITION...1 9. 1011.12 13. 14 I. 16 17.18 19.20 21.22 23.24 25".26 27.28129.30 .31 D.B./W.B. pDy nulbFWetI ulbOew Porn , 34/ 33 289 32/3R1 _ I jJ _, _ 267 30

  17. Paratextual Transactions: Text and Off Text in William Blake’s Milton and Jerusalem

    Directory of Open Access Journals (Sweden)

    Annalisa Volpone

    2016-07-01

    Full Text Available Il saggio si concentra sulle dinamiche tra testo e paratesto negli ultimi due libri profetici di William Blake, Milton e Jerusalem. A partire dalle riflessioni di Genette in Soglie, si ragionerà su come parola e immagine interagiscono nelle tavole e concorrono a produrre significato. I libri profetici, in quanto opera d’arte “integrata”, implicano una partecipazione attiva da parte del lettore, che deve saper interpretare i molteplici livelli di interazione tra le componenti testuali e paratestuali, all’interno della complessa cornice rappresentata dalla letteratura apocalittica alla quale l’ultima produzione di Blake appartiene.

  18. Cultura comum, reflexões acerca da obra de Raymond Williams

    Directory of Open Access Journals (Sweden)

    Carlos Eduardo Amaral Paiva

    2014-11-01

    Full Text Available Por meio da análise de alguns conceitos chaves desenvolvidos pelo crítico literário Raymond Williams, tais como estrutura-superestrutura, hegemonia e cultura comum, busca-se compreender o significado de parte da obra do autor dentro do projeto político dos estudos culturais. Assim, a ideia de cultura como prática do vivido, adotada pelo crítico, faz parte de uma concepção não elitista de cultura se apresentando como uma postura política-epistemológica vinculada à sua vivência e ideais socialistas.

  19. Cultura comum, reflexões acerca da obra de Raymond Williams

    OpenAIRE

    Carlos Eduardo Amaral Paiva

    2014-01-01

    Por meio da análise de alguns conceitos chaves desenvolvidos pelo crítico literário Raymond Williams, tais como estrutura-superestrutura, hegemonia e cultura comum, busca-se compreender o significado de parte da obra do autor dentro do projeto político dos estudos culturais. Assim, a ideia de cultura como prática do vivido, adotada pelo crítico, faz parte de uma concepção não elitista de cultura se apresentando como uma postura política-epistemológica vinculada à sua vivência e ideais sociali...

  20. Estrutura e significado em "Uma rosa para Emily", de William Faulkner

    OpenAIRE

    Daghlian,Carlos

    2004-01-01

    Trata-se de uma análise do consagrado conto "Uma Rosa para Emily", de William Faulkner, voltada para alguns dos principais aspectos de sua estrutura. Após considerarmos o enredo, discutimos a construção das personagens, com destaque para a protagonista, fazendo um levantamento e comentários sobre possíveis fontes de inspiração, destacando, entre outras, aspectos da biografia da poeta Emily Dickinson, a ficção e a poesia de E. A. Poe, romances de Charles Dickens e Henry James, o conto de Sherw...

  1. Anesthesiological Management of a Patient with Williams Syndrome Undergoing Spine Surgery

    Directory of Open Access Journals (Sweden)

    Federico Boncagni

    2016-01-01

    Full Text Available Williams Syndrome (WS is a complex neurodevelopmental disorder associated with a mutation on chromosome 7. Patients with WS usually display dysmorphic facial and musculoskeletal features, congenital heart diseases, metabolic disturbances and cognitive impairment. Structural cardiovascular abnormalities are present in the majority of the children and may provide a substrate for perioperative Sudden Cardiac Death, as presented by several reports, something that creates a great challenge to the anesthetic conduct. We present the case of a 12-year old girl who required anesthetic care for surgical correction of an acquired kyphoscoliosis. Potential anesthesiological implications of WS are subsequently reviewed.

  2. Early Manifestation of Supravalvular Aortic and Pulmonary Artery Stenosis in a Patient with Williams Syndrome

    Directory of Open Access Journals (Sweden)

    Jong Uk Lee

    2016-04-01

    Full Text Available Williams syndrome (WS is a developmental disorder characterized by vascular abnormalities such as thickening of the vascular media layer in medium- and large-sized arteries. Supravalvular aortic stenosis (SVAS and peripheral pulmonary artery stenosis (PPAS are common vascular abnormalities in WS. The natural course of SVAS and PPAS is variable, and the timing of surgery or intervention is determined according to the progression of vascular stenosis. In our patient, SVAS and PPAS showed rapid concurrent progression within two weeks after birth. We report the early manifestation of SVAS and PPAS in the neonatal period and describe the surgical treatment for stenosis relief.

  3. Improving the Weizsäcker-Williams approximation in electron-proton collisions

    CERN Document Server

    Frixione, Stefano; Nason, P; Ridolfi, G

    1993-01-01

    We critically examine the validity of the Weizs\\"acker-Williams approximation in electron-hadron collisions. We show that in its commonly used form it can lead to large errors, and we show how to improve it in order to get accurate results. In particular, we present an improved form that is valid beyond the leading logarithmic approximation in the case when a small-angle cut is applied to the scattered electron. Furthermore we include comparisons of the approximate expressions with the exact electroproduction calculation in the case of heavy-quark production.

  4. The book classification of William Torrey Harris: influences of Bacon and Hegel in library classification

    Directory of Open Access Journals (Sweden)

    Rodrigo de Sales

    2017-09-01

    Full Text Available The studies of library classification generally interact with the historical contextualization approach and with the classification ideas typical of Philosophy. In the 19th century, the North-American philosopher and educator William Torrey Harris developed a book classification at the St. Louis Public School, based on Francis Bacon and Georg Wilhelm Friedrich Hegel. The objective of this essay is to analyze Harris’s classification, reflecting upon his theoretical and philosophical backgrounds. To achieve such objective, this essay adopts a critical-descriptive approach for analysis. Results show some influences of Bacon and Hegel in Harris’s classification.

  5. Ian D. Copestake, The Ethics of William Carlos Williams’s Poetry.

    Directory of Open Access Journals (Sweden)

    Aristotle University of Greece

    2011-09-01

    Full Text Available Ian D. Copestake’s monograph on William Carlos Williams’s poetry offers a well-informed and well-documented insight into the connection between Williams’s writing with Unitarianism and Emersonian thinking. In this very well-written and accessible book, the reader gets introduced to a number of poems in addition to excerpts from Williams’s essays, letters and autobiography which facilitate the understanding and appreciation of the poet’s attempt to promote “independent thought and action” (5....

  6. Plasticidad cerebral y hábito en William James: un antecedente para la Neurociencia Social

    OpenAIRE

    Alcover, Carlos-María; Rodríguez, Fernando

    2012-01-01

    En el capítulo dedicado al hábito de los Principios de Psicología (1890) William James introducía como concepto clave la plasticidad del sistema nervioso y del cerebro, un fenómeno que experimentalmente él no podía estudiar, pero que era una consecuencia derivada de los resultados de las investigaciones contemporáneas en diversos campos de la Biología y la Fisiología. La plasticidad hace referencia a cómo el aprendizaje, la adquisición de habilidades, las influencias interpersonal...

  7. Business Solutions Case Study: Marketing Zero Energy Homes: Tommy Williams Homes, Gainesville, Florida

    Energy Technology Data Exchange (ETDEWEB)

    None

    2015-06-01

    Building America research has shown that high-performance homes can potentially give builders an edge in the marketplace and can boost sales, but it doesn't happen automatically. It requires a tailored, easy-to-understand marketing campaign, and sometimes a little flair. This case study highlights the successful marketing approach of Tommy Williams Homes, which devotes resources to advertising, targeted social media outlets and blogs, realtor education seminars, and groundbreaking and open house celebrations. As a result, in one community, 2013 property sales records show that TWH outsells the only other builder in the development at a higher price, with fewer days on the market.

  8. The Blantyre bonesetter: William Rae's rise to fame and the popular press.

    Science.gov (United States)

    Bovine, G

    2012-05-01

    William Rae (1841-1907) was a bonesetter in Blantyre near Glasgow who quietly practised and treated the local people of the region in relative obscurity. In 1904, the popular press became aware of his work, and after they printed stories of his skills and cures Rae was flocked by patients from the surrounding regions. The stories were then copied by newspapers in England, the USA, Australia and New Zealand, and Rae became internationally known. This article gives a historical look at Rae, his patients and his methods of treatment, as well as the medical views on bonesetting and this individual.

  9. Danish resonances and repercussions in the life and work of William H. Johnson

    DEFF Research Database (Denmark)

    Sørensen, Bent

    William H. Johnson was an outstanding African-American artist, represented with hundreds of works in the Smithsonian Museum of American Art’s collection, but he was also a resident of Denmark for the better part of the 1930s, and again for a brief spell after WWII. While studying art in Paris...... and the rest of Scandinavia in that period. I shall take a look at the reception of his work (and that of Holcha Krake) in all three Scandinavian countries (they both spent considerable time in Norway and Sweden as well as in Holcha’s native Denmark) which routinely exoticizes Johnson and his art in language...

  10. Efectividad de la microonda, masoterapia y ejercicios de Williams en pacientes con dolor lumbar

    OpenAIRE

    Antonio del Valle Torres; Nadia Rosa Hechavarría Almaguer; Carlos López Peña; Raúl Barceló Reyna

    2015-01-01

    Fundamento: el dolor lumbar constituye un problema de salud a nivel mundial, su tratamiento constituye un reto en la práctica médica asistencial. Objetivo: evaluar la efectividad de la microonda, masoterapia y ejercicios de Williams en pacientes con dolor lumbar. Método: se realizó un estudio prospectivo experimental en una muestra de 60 pacientes con lumbalgia subaguda y crónica. Se asignaron dos esquemas de tratamiento: uno con microonda combinada con masoterapia y ejercicios de Wil...

  11. William Dab, Danielle Salomon, Agir face aux risques sanitaires. Pour un pacte de confiance

    OpenAIRE

    Vieira Bertho, Isabela

    2016-01-01

    Écrit à deux mains, « Agir face aux risques sanitaires » présente une réflexion sur la gestion actuelle des risques sanitaires en France. Les auteurs William Dab, ancien directeur général de la santé en France et actuel directeur de l’École des sciences industrielles et technologies de l’information au Conservatoire national des arts et métiers (CNAM) et Danielle Salomon, sociologue des organisations et des risques, offrent dans ce livre une analyse de la politique sécuritaire sanitaire franç...

  12. [Cross-linguistic assessment of verbal production from a narrative task in Williams Syndrome].

    Science.gov (United States)

    Garayzábal Heinze, Elena; Prieto, Montse F; Sampaio, Adriana; Gonçalves, Oscar

    2007-08-01

    Williams Syndrome (WS) is a disorder caused by a delection in chromosome 7, with a cognitive profile characterised by mild to moderate mental deficiency and difficulties in visual-spatial processing, which contrasts with a relative preservation of linguistic functions and narrative production. In this study, verbal performance was analysed in two groups of participants (N = 3), Portuguese and Spanish, genetically diagnosed with WS. Scores were low in Verbal IQ, as in Performance IQ. Narrative performance showed low coherence with respect to structure, process, and content. WS verbal performance was affected and there was no difference between both groups. We could not find any dissociation between cognitive functioning and linguistic production.

  13. On the application of the Williams-Weizsaecker-method to higher order S-matrix-approximations

    International Nuclear Information System (INIS)

    Ziegelbecker, R.C.

    1983-05-01

    In this paper the method of quasireal processes is investigated using a special example - pair production in the stationary field of a nucleus by an incident electron. As a result, the semi-classical version of the Williams-Weizsaecker-method is confirmed on the basis of all 3sup(rd)-order Feynman-diagrams. The spectra of quasireal processes, derived from quantum field theory, can also be applied simultaneously in several vertex points on one diagram and are valid for higher photon energies than the semiclassical spectrum; the restriction #betta# [de

  14. Williams Element with Generalized Degrees of Freedom for Fracture Analysis of Multiple-Cracked Beam

    Science.gov (United States)

    Xu, Hua; Wei, Quyang; Yang, Lufeng

    2017-10-01

    In this paper, the method of finite element with generalized degrees of freedom (FEDOFs) is used to calculate the stress intensity factor (SIF) of multiple cracked beam and analysed the effect of minor cracks on the main crack SIF in different cases. Williams element is insensitive to the size of singular region. So that calculation efficiency is highly improved. Examples analysis validates that the SIF near the crack tip can be obtained directly though FEDOFs. And the result is well consistent with ANSYS solution and has a satisfied accuracy.

  15. Memory profiles of Down, Williams, and fragile X syndromes: implications for reading development.

    Science.gov (United States)

    Conners, Frances A; Moore, Marie S; Loveall, Susan J; Merrill, Edward C

    2011-06-01

    The purpose of this review was to understand the types of memory impairments that are associated with intellectual disability (ID, formerly called mental retardation) and the implications of these impairments for reading development. Specifically, studies on working memory, delayed memory and learning, and semantic/conceptual memory in Down syndrome, Williams syndrome, and fragile X syndrome were examined. A distinct memory profile emerged for each of the 3 etiologies of ID. Memory profiles are discussed in relation to strengths and weaknesses in reading skills in these three etiologies. We suggest that reading instruction be designed to capitalize on relatively stronger memory skills while providing extra support for especially challenging aspects of reading.

  16. A critical comparison of William James and Søren Kierkegaard on religious belief

    OpenAIRE

    Chipp, Jonathan

    2009-01-01

    This thesis is a critical comparison of the accounts of religious belief proposed byWilliam James and Søren Kierkegaard. Both James and Kierkegaard greatly emphasizethe subjective aspects of religious belief. In view of this fact, surprisingly littlecomparative work has been done in this area. I contribute to this literature in two ways.Firstly, I make a brief assessment of what James knew of Kierkegaard’s work.Secondly, I draw four comparisons between Kierkegaard and James. In Chapter One Ie...

  17. Tema, estructura y marco narrativo en "Luz de Agosto" de William Faulkner

    OpenAIRE

    Herrero Villapalos, Rosa

    2004-01-01

    Este trabajo tiene como objeto el estudio del tema, la estructura y el marco narrativo en Luz de Agosto de William Faulkner a través de sus personajes. Aunque son Christmas, Lena y Hightower los tres personajes principales en los que se concentra la historia, es Joe Christmas el verdadero motor que hace fluir el relato, él es el hilo en donde se van engarzando las diferentes piezas de historia personaje. Por otra parte, Faulkner utiliza a Lena y su itinerario -de Alabama a Tennesse- como marc...

  18. Alternative treatment for open bite Class III malocclusion in a child with Williams-Beuren syndrome.

    Science.gov (United States)

    Vieira, Giovanni Modesto; Franco, Eduardo Jacomino; da Rocha, Denise Falcão Pinheiro; de Oliveira, Laudimar Alves; Amorim, Rivadávio Fernandes Batista

    2015-01-01

    Williams-Beuren syndrome (WBS) is a rare genetic condition that affects approximately 1 in every 20,000 - 50,000 live births. WBS children have specific skeletal deformities, dental malformations and rare lingual muscle dysfunction. The need for orthodontic and orthognathic therapy has arisen and has been considered a real clinical challenge even for experienced professionals, once it requires a complex and individualized treatment plan. This study reports a case of orthopedic expansion of the maxilla, in which a modified facial mask was used for protraction of the maxillary complex associated with clockwise rotation of the maxilla. In addition, special considerations about treatment time and orthopedic outcomes are discussed.

  19. William Halse Rivers Rivers (1864-1922) and the sensory nervous system.

    Science.gov (United States)

    Pearce, J M S

    2008-01-01

    The polymath William Rivers played an important role in his work with Henry Head in demonstrating the varied, evolving patterns of sensory loss, and epicritic and protopathic sensation, after the section of the superficial ramus of Head's left radial nerve. After a mixed and frustrated army career Rivers devoted his attentions to shell shock and other psychological disturbances which were well received in his time. Siegfried Sassoon and Wilfred Owen were among the distinguished patients whose writings revealed Rivers as the revered object of their gratitude. Copyright 2008 S. Karger AG, Basel.

  20. Monitoring oiled shorelines in Prince William Sound Alaska, following the Exxon Valdez oil spill

    International Nuclear Information System (INIS)

    Gilfillan, E.S.; Page, D.S.; Harner, E.J.; Boehm, P.D.; Stoker, S.W.

    1993-01-01

    Three types of shoreline monitoring programs were employed to evaluate the recovery of the ecological communities of Prince William Sound (PWS) shorelines after the oil spill: (a) Extensive shoreline surveys conducted (1989--1992) over much of the oiled shoreline to define extent of shoreline oiling and to assess biological conditions; (b) Detailed sampling in 1989 at nonrandomly chosen locations representing a range of oiling conditions (c) Comprehensive shoreline ecology program initiated in 1990 to assess shoreline recovery in Prince William Sound using (1) a rigorous stratified random sampling study design with 64 sites representing 4 shoreline habitats and 4 oiling levels (unoiled, light, moderate, heavy); (2) periodic sampling at 12 nonrandomly chosen sites of particular concern. Biological communities were analyzed to detect differences due to oiling in each of 16 habitat/tide zone combinations. Following the spill, populations of all major species survived as sources for recolonization. Recruitment to oiled shores began in summer 1989. By 1990, shoreline biota in PWS had largely recovered. Estimates of shoreline recovery (biological community indistinguishable from reference) ranged from 91% based on univariate analysis of standard community parameters to 73% based on multivariate correspondence analysis