WorldWideScience

Sample records for modeling study-1978 volume

  1. Computational Model for Spacecraft/Habitat Volume

    Data.gov (United States)

    National Aeronautics and Space Administration — Please note that funding to Dr. Simon Hsiang, a critical co-investigator for the development of the Spacecraft Optimization Layout and Volume (SOLV) model, was...

  2. Dark radiation in LARGE volume models

    Science.gov (United States)

    Cicoli, Michele; Conlon, Joseph P.; Quevedo, Fernando

    2013-02-01

    We consider reheating driven by volume modulus decays in the LARGE volume scenario. Such reheating always generates nonzero dark radiation through the decays to the axion partner, while the only competitive visible sector decays are Higgs pairs via the Giudice-Masiero term. In the framework of sequestered models where the cosmological moduli problem is absent, the simplest model with a shift-symmetric Higgs sector generates 1.56≤ΔNeff≤1.74. For more general cases, the known experimental bounds on ΔNeff strongly constrain the parameters and matter content of the models.

  3. EARTHWORK VOLUME CALCULATION FROM DIGITAL TERRAIN MODELS

    Directory of Open Access Journals (Sweden)

    JANIĆ Milorad

    2015-06-01

    Full Text Available Accurate calculation of cut and fill volume has an essential importance in many fields. This article shows a new method, which has no approximation, based on Digital Terrain Models. A relatively new mathematical model is developed for that purpose, which is implemented in the software solution. Both of them has been tested and verified in the praxis on several large opencast mines. This application is developed in AutoLISP programming language and works in AutoCAD environment.

  4. 1988 DOE model conference proceedings: Volume 4

    Energy Technology Data Exchange (ETDEWEB)

    1988-01-01

    These Proceedings of the October 3-7, 1988, DOE Model Conference are a compilation of the papers that were presented in the technical or poster sessions at the conference. Papers and posters not submitted for publication are not included in the Proceedings. The Table of Contents lists the titles of papers as well as the names of the presenters. These individuals are not, in all cases, the primary authors of the papers published. The actual title pages, appearing later with the papers, show the primary author(s) and all co-authors. The papers in all three volumes of the Proceedings appear as they were originally submitted for publication and have not been edited or changed in any way. Topics discussed in Volume 4 include site characterization and remediation projects, environmental monitoring and modeling; disposal site selection and facility design, risk assessment, safety and health issues, and site remediation technology.

  5. 1988 DOE model conference proceedings: Volume 4

    International Nuclear Information System (INIS)

    1988-01-01

    These Proceedings of the October 3-7, 1988, DOE Model Conference are a compilation of the papers that were presented in the technical or poster sessions at the conference. Papers and posters not submitted for publication are not included in the Proceedings. The Table of Contents lists the titles of papers as well as the names of the presenters. These individuals are not, in all cases, the primary authors of the papers published. The actual title pages, appearing later with the papers, show the primary author(s) and all co-authors. The papers in all three volumes of the Proceedings appear as they were originally submitted for publication and have not been edited or changed in any way. Topics discussed in Volume 4 include site characterization and remediation projects, environmental monitoring and modeling; disposal site selection and facility design, risk assessment, safety and health issues, and site remediation technology

  6. Effects of uncertainty in model predictions of individual tree volume on large area volume estimates

    Science.gov (United States)

    Ronald E. McRoberts; James A. Westfall

    2014-01-01

    Forest inventory estimates of tree volume for large areas are typically calculated by adding model predictions of volumes for individual trees. However, the uncertainty in the model predictions is generally ignored with the result that the precision of the large area volume estimates is overestimated. The primary study objective was to estimate the effects of model...

  7. Modeling nuclear volume isotope effects in crystals

    Science.gov (United States)

    Schauble, Edwin A.

    2013-01-01

    Mass-independent isotope fractionations driven by differences in volumes and shapes of nuclei (the field shift effect) are known in several elements and are likely to be found in more. All-electron relativistic electronic structure calculations can predict this effect but at present are computationally intensive and limited to modeling small gas phase molecules and clusters. Density functional theory, using the projector augmented wave method (DFT-PAW), has advantages in greater speed and compatibility with a three-dimensional periodic boundary condition while preserving information about the effects of chemistry on electron densities within nuclei. These electron density variations determine the volume component of the field shift effect. In this study, DFT-PAW calculations are calibrated against all-electron, relativistic Dirac–Hartree–Fock, and coupled-cluster with single, double (triple) excitation methods for estimating nuclear volume isotope effects. DFT-PAW calculations accurately reproduce changes in electron densities within nuclei in typical molecules, when PAW datasets constructed with finite nuclei are used. Nuclear volume contributions to vapor–crystal isotope fractionation are calculated for elemental cadmium and mercury, showing good agreement with experiments. The nuclear-volume component of mercury and cadmium isotope fractionations between atomic vapor and montroydite (HgO), cinnabar (HgS), calomel (Hg2Cl2), monteponite (CdO), and the CdS polymorphs hawleyite and greenockite are calculated, indicating preferential incorporation of neutron-rich isotopes in more oxidized, ionically bonded phases. Finally, field shift energies are related to Mössbauer isomer shifts, and equilibrium mass-independent fractionations for several tin-bearing crystals are calculated from 119Sn spectra. Isomer shift data should simplify calculations of mass-independent isotope fractionations in other elements with Mössbauer isotopes, such as platinum and uranium

  8. 1988 DOE model conference proceedings: Volume 2

    International Nuclear Information System (INIS)

    1988-01-01

    These Proceedings of the October 3 - 7, 1988, DOE Model Conference are a compilation of the papers that were presented in the technical or poster sessions at the conference. Papers and posters not submitted for publication are not included in the proceedings. The Table of Contents lists the titles of papers as well as the names of the presenters. These individuals are not, in all cases, the primary authors of the papers published. The actual title pages, appearing later with the papers, show the primary author(s) and all co-authors. The papers in all three volumes of the Proceedings appear as they were originally submitted for publication and have not been edited or changed in any way. Volume 2 contains information on environmental restoration at federal facilities, waste disposal technology, quality assurance, contingency planning and emergency response, decontamination and decommissioning, environmental restoration, and public involvement in waste management

  9. 1988 DOE model conference proceedings: Volume 3

    Energy Technology Data Exchange (ETDEWEB)

    1988-01-01

    These Proceedings of the October 3 - 7, 1988, DOE Model Conference are a compilation of the papers that were presented in the technical or poster sessions at the conference. Papers and posters not submitted for publication are not included in the Proceedings. The Table of Contents lists the titles of papers as well as the names of the presenters. These individuals are not, in all cases, the primary authors of the papers published. The actual title pages, appearing later with the papers, show the primary author(s) and all co-authors. The papers in all three volumes of the proceedings appear as they were originally submitted for publication and have not been edited or changed in any way. Topics included in Volume 3 include treatment of soils, waste characterization and certification, waste minimization site remediation management plans and programs, and training programs.

  10. 1988 DOE model conference proceedings: Volume 3

    International Nuclear Information System (INIS)

    1988-01-01

    These Proceedings of the October 3 - 7, 1988, DOE Model Conference are a compilation of the papers that were presented in the technical or poster sessions at the conference. Papers and posters not submitted for publication are not included in the Proceedings. The Table of Contents lists the titles of papers as well as the names of the presenters. These individuals are not, in all cases, the primary authors of the papers published. The actual title pages, appearing later with the papers, show the primary author(s) and all co-authors. The papers in all three volumes of the proceedings appear as they were originally submitted for publication and have not been edited or changed in any way. Topics included in Volume 3 include treatment of soils, waste characterization and certification, waste minimization site remediation management plans and programs, and training programs

  11. 1988 DOE model conference proceedings: Volume 1

    International Nuclear Information System (INIS)

    1988-01-01

    These Proceedings of the October 3-7, 1988, DOE Model Conference are a compilation of the papers that were presented in the technical or poster sessions at the conference. Papers and posters not submitted for publication are not included in the Proceedings. The Table of Contents lists the titles of papers as well as the names of the presenters. These individuals are not, in all cases, the primary authors of the papers published. The actual title pages, appearing later with the papers, show the primary author(s) and all co-authors. The papers in all three volumes of the Proceedings appear as they were originally submitted for publication and have not been edited or changed in any way. Topics included in Volume 1 are Environmental Data Management, Site characterization technology, Wastewater treatment, Waste management in foreign countries, Transuranic waste management, and Groundwater characterization and treatment

  12. 1988 DOE model conference proceedings: Volume 5

    International Nuclear Information System (INIS)

    1988-01-01

    These Proceedings of the October 3--7, 1988 DOE Model Conference are a compilation of the papers that were presented in the technical or poster sessions at the conference papers and posters not submitted for publication are not included in the Proceedings. The Table of Contents lists the titles of papers as well as the names of the presenters. These individuals are not, in all cases, the primary authors of the papers published. The actual title pages, appearing later with the papers, show the primary author(s) and all co-authors. The papers in all three volumes of the Proceedings appear as they were originally submitted for publication and have not been edited or changed in any way. Topics discussed in Volume 5 include environmental assessments and program strategies, waste treatment technologies, and regulations and compliance studies

  13. 1988 DOE model conference proceedings: Volume 5

    Energy Technology Data Exchange (ETDEWEB)

    1988-01-01

    These Proceedings of the October 3--7, 1988 DOE Model Conference are a compilation of the papers that were presented in the technical or poster sessions at the conference papers and posters not submitted for publication are not included in the Proceedings. The Table of Contents lists the titles of papers as well as the names of the presenters. These individuals are not, in all cases, the primary authors of the papers published. The actual title pages, appearing later with the papers, show the primary author(s) and all co-authors. The papers in all three volumes of the Proceedings appear as they were originally submitted for publication and have not been edited or changed in any way. Topics discussed in Volume 5 include environmental assessments and program strategies, waste treatment technologies, and regulations and compliance studies.

  14. 1988 DOE model conference proceedings: Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    1988-01-01

    These Proceedings of the October 3-7, 1988, DOE Model Conference are a compilation of the papers that were presented in the technical or poster sessions at the conference. Papers and posters not submitted for publication are not included in the Proceedings. The Table of Contents lists the titles of papers as well as the names of the presenters. These individuals are not, in all cases, the primary authors of the papers published. The actual title pages, appearing later with the papers, show the primary author(s) and all co-authors. The papers in all three volumes of the Proceedings appear as they were originally submitted for publication and have not been edited or changed in any way. Topics included in Volume 1 are Environmental Data Management, Site characterization technology, Wastewater treatment, Waste management in foreign countries, Transuranic waste management, and Groundwater characterization and treatment.

  15. Atmospheric Renewable Energy Research, Volume 5 (Solar Radiation Flux Model)

    Science.gov (United States)

    2017-09-01

    ARL-TR-8155 ● SEP 2017 US Army Research Laboratory Atmospheric Renewable Energy Research, Volume 5 (Solar Radiation Flux Model... Energy Research, Volume 5 (Solar Radiation Flux Model) by Clayton Walker and Gail Vaucher Computational and Information Sciences Directorate, ARL...2017 June 28 4. TITLE AND SUBTITLE Atmospheric Renewable Energy Research, Volume 5 (Solar Radiation Flux Model) 5a. CONTRACT NUMBER ROTC Internship

  16. A method for mapping tissue volume model onto target volume using volumetric self-organizing deformable model

    Science.gov (United States)

    Miyauchi, Shoko; Morooka, Ken'ichi; Tsuji, Tokuo; Miyagi, Yasushi; Fukuda, Takaichi; Kurazume, Ryo

    2016-03-01

    This paper proposes a new method for mapping volume models of human tissues onto a target volume with simple shapes. The proposed method is based on our modified self-organizing deformable model (mSDM)1, 2 which finds the one-to-one mapping with no foldovers between arbitrary surface model and a target surface. By extending mSDM to apply to volume models, the proposed method, called volumetric SDM (vSDM), establishes the one-to-one correspondence between the tissue volume model and its target volume. At the same time, vSDM can preserve geometrical properties of the original model before and after mapping. This characteristic of vSDM makes it easy to find the correspondence between tissue models.

  17. Total tree, merchantable stem and branch volume models for ...

    African Journals Online (AJOL)

    Total tree, merchantable stem and branch volume models for miombo woodlands of Malawi. Daud J Kachamba, Tron Eid. Abstract. The objective of this study was to develop general (multispecies) models for prediction of total tree, merchantable stem and branch volume including options with diameter at breast height (dbh) ...

  18. Comparison of actual tidal volume in neonatal lung model volume control ventilation using three ventilators.

    Science.gov (United States)

    Toyama, H; Endo, Y; Ejima, Y; Matsubara, M; Kurosawa, S

    2011-07-01

    In neonates, small changes in tidal volumes (V(T)) may lead to complications. Previous studies have shown a significant difference between ventilator-measured tidal volume and tidal volume delivered (actual V(T)). We evaluated the accuracy of three different ventilators to deliver small V(T) during volume-controlled ventilation. We tested Servo 300, 840 ventilator and Evita 4 Neoflow ventilators with lung models simulating normal and injured neonatal lung compliance models. Gas volume delivered from the ventilator into the test circuit (V(TV)) and actual V(T) to the test lung were measured using Ventrak respiration monitors at set V(T) (30 ml). The gas volume increase of the breathing circuit was then calculated. Tidal volumes of the SV300 and PB840 in both lung models were similar to the set V(T) and the actual tidal volumes in the injured model (20.7 ml and 19.8 ml, respectively) were significantly less than that in the normal model (27.4 ml and 23.4 ml). PB840 with circuit compliance compensation could not improve the actual V(T). V(TV) of the EV4N in the normal and the injured models (37.8 ml and 46.6 ml) were markedly increased compared with set V(T), and actual V(T) were similar to set V(T) in the normal and injured model (30.2 ml and 31.9 ml, respectively). EV4N measuring V(T) close to the lung could match actual V(T) to almost the same value as the set V(T) however the gas volume of the breathing circuit was increased. If an accurate value for the patient's actual V(T) is needed, this V(T) must be measured by a sensor located between the Y-piece and the tracheal tube.

  19. 1987 Oak Ridge model conference: Proceedings: Volume 2, Environmental protection

    International Nuclear Information System (INIS)

    1987-01-01

    See the abstract for Volume I for general information on the conference. Topics discussed in Volume II include data management techiques for environmental protection efforts, the use of models in environmental auditing, in emergency plans, chemical accident emergency response, risk assessment, monitoring of waste sites, air and water monitoring of waste sites, and in training programs

  20. Disc volume reduction with percutaneous nucleoplasty in an animal model.

    Directory of Open Access Journals (Sweden)

    Richard Kasch

    Full Text Available STUDY DESIGN: We assessed volume following nucleoplasty disc decompression in lower lumbar spines from cadaveric pigs using 7.1Tesla magnetic resonance imaging (MRI. PURPOSE: To investigate coblation-induced volume reductions as a possible mechanism underlying nucleoplasty. METHODS: We assessed volume following nucleoplastic disc decompression in pig spines using 7.1-Tesla MRI. Volumetry was performed in lumbar discs of 21 postmortem pigs. A preoperative image data set was obtained, volume was determined, and either disc decompression or placebo therapy was performed in a randomized manner. Group 1 (nucleoplasty group was treated according to the usual nucleoplasty protocol with coblation current applied to 6 channels for 10 seconds each in an application field of 360°; in group 2 (placebo group the same procedure was performed but without coblation current. After the procedure, a second data set was generated and volumes calculated and matched with the preoperative measurements in a blinded manner. To analyze the effectiveness of nucleoplasty, volumes between treatment and placebo groups were compared. RESULTS: The average preoperative nucleus volume was 0.994 ml (SD: 0.298 ml. In the nucleoplasty group (n = 21 volume was reduced by an average of 0.087 ml (SD: 0.110 ml or 7.14%. In the placebo group (n = 21 volume was increased by an average of 0.075 ml (SD: 0.075 ml or 8.94%. The average nucleoplasty-induced volume reduction was 0.162 ml (SD: 0.124 ml or 16.08%. Volume reduction in lumbar discs was significant in favor of the nucleoplasty group (p<0.0001. CONCLUSIONS: Our study demonstrates that nucleoplasty has a volume-reducing effect on the lumbar nucleus pulposus in an animal model. Furthermore, we show the volume reduction to be a coblation effect of nucleoplasty in porcine discs.

  1. Fixed site neutralization model programmer's manual. Volume II

    International Nuclear Information System (INIS)

    Engi, D.; Chapman, L.D.; Judnick, W.; Blum, R.; Broegler, L.; Lenz, J.; Weinthraub, A.; Ballard, D.

    1979-12-01

    This report relates to protection of nuclear materials at nuclear facilities. This volume presents the source listings for the Fixed Site Neutralization Model and its supporting modules, the Plex Preprocessor and the Data Preprocessor

  2. Ovarian volume throughout life: a validated normative model.

    Science.gov (United States)

    Kelsey, Thomas W; Dodwell, Sarah K; Wilkinson, A Graham; Greve, Tine; Andersen, Claus Y; Anderson, Richard A; Wallace, W Hamish B

    2013-01-01

    The measurement of ovarian volume has been shown to be a useful indirect indicator of the ovarian reserve in women of reproductive age, in the diagnosis and management of a number of disorders of puberty and adult reproductive function, and is under investigation as a screening tool for ovarian cancer. To date there is no normative model of ovarian volume throughout life. By searching the published literature for ovarian volume in healthy females, and using our own data from multiple sources (combined n=59,994) we have generated and robustly validated the first model of ovarian volume from conception to 82 years of age. This model shows that 69% of the variation in ovarian volume is due to age alone. We have shown that in the average case ovarian volume rises from 0.7 mL (95% CI 0.4-1.1 mL) at 2 years of age to a peak of 7.7 mL (95% CI 6.5-9.2 mL) at 20 years of age with a subsequent decline to about 2.8 mL (95% CI 2.7-2.9 mL) at the menopause and smaller volumes thereafter. Our model allows us to generate normal values and ranges for ovarian volume throughout life. This is the first validated normative model of ovarian volume from conception to old age; it will be of use in the diagnosis and management of a number of diverse gynaecological and reproductive conditions in females from birth to menopause and beyond.

  3. Optimized volume models of earthquake-triggered landslides.

    Science.gov (United States)

    Xu, Chong; Xu, Xiwei; Shen, Lingling; Yao, Qi; Tan, Xibin; Kang, Wenjun; Ma, Siyuan; Wu, Xiyan; Cai, Juntao; Gao, Mingxing; Li, Kang

    2016-07-12

    In this study, we proposed three optimized models for calculating the total volume of landslides triggered by the 2008 Wenchuan, China Mw 7.9 earthquake. First, we calculated the volume of each deposit of 1,415 landslides triggered by the quake based on pre- and post-quake DEMs in 20 m resolution. The samples were used to fit the conventional landslide "volume-area" power law relationship and the 3 optimized models we proposed, respectively. Two data fitting methods, i.e. log-transformed-based linear and original data-based nonlinear least square, were employed to the 4 models. Results show that original data-based nonlinear least square combining with an optimized model considering length, width, height, lithology, slope, peak ground acceleration, and slope aspect shows the best performance. This model was subsequently applied to the database of landslides triggered by the quake except for two largest ones with known volumes. It indicates that the total volume of the 196,007 landslides is about 1.2 × 10(10) m(3) in deposit materials and 1 × 10(10) m(3) in source areas, respectively. The result from the relationship of quake magnitude and entire landslide volume related to individual earthquake is much less than that from this study, which reminds us the necessity to update the power-law relationship.

  4. Model documentation Natural Gas Transmission and Distribution Model of the National Energy Modeling System. Volume 1

    International Nuclear Information System (INIS)

    1996-01-01

    The Natural Gas Transmission and Distribution Model (NGTDM) of the National Energy Modeling System is developed and maintained by the Energy Information Administration (EIA), Office of Integrated Analysis and Forecasting. This report documents the archived version of the NGTDM that was used to produce the natural gas forecasts presented in the Annual Energy Outlook 1996, (DOE/EIA-0383(96)). The purpose of this report is to provide a reference document for model analysts, users, and the public that defines the objectives of the model, describes its basic approach, and provides detail on the methodology employed. Previously this report represented Volume I of a two-volume set. Volume II reported on model performance, detailing convergence criteria and properties, results of sensitivity testing, comparison of model outputs with the literature and/or other model results, and major unresolved issues

  5. Model documentation Natural Gas Transmission and Distribution Model of the National Energy Modeling System. Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-02-26

    The Natural Gas Transmission and Distribution Model (NGTDM) of the National Energy Modeling System is developed and maintained by the Energy Information Administration (EIA), Office of Integrated Analysis and Forecasting. This report documents the archived version of the NGTDM that was used to produce the natural gas forecasts presented in the Annual Energy Outlook 1996, (DOE/EIA-0383(96)). The purpose of this report is to provide a reference document for model analysts, users, and the public that defines the objectives of the model, describes its basic approach, and provides detail on the methodology employed. Previously this report represented Volume I of a two-volume set. Volume II reported on model performance, detailing convergence criteria and properties, results of sensitivity testing, comparison of model outputs with the literature and/or other model results, and major unresolved issues.

  6. Spatial Economics Model Predicting Transport Volume

    Directory of Open Access Journals (Sweden)

    Lu Bo

    2016-10-01

    Full Text Available It is extremely important to predict the logistics requirements in a scientific and rational way. However, in recent years, the improvement effect on the prediction method is not very significant and the traditional statistical prediction method has the defects of low precision and poor interpretation of the prediction model, which cannot only guarantee the generalization ability of the prediction model theoretically, but also cannot explain the models effectively. Therefore, in combination with the theories of the spatial economics, industrial economics, and neo-classical economics, taking city of Zhuanghe as the research object, the study identifies the leading industry that can produce a large number of cargoes, and further predicts the static logistics generation of the Zhuanghe and hinterlands. By integrating various factors that can affect the regional logistics requirements, this study established a logistics requirements potential model from the aspect of spatial economic principles, and expanded the way of logistics requirements prediction from the single statistical principles to an new area of special and regional economics.

  7. Mathematical models for volume rendering and neutron transport

    International Nuclear Information System (INIS)

    Max, N.

    1994-09-01

    This paper reviews several different models for light interaction with volume densities of absorbing, glowing, reflecting, or scattering material. They include absorption only, glow only, glow and absorption combined, single scattering of external illumination, and multiple scattering. The models are derived from differential equations, and illustrated on a data set representing a cloud. They are related to corresponding models in neutron transport. The multiple scattering model uses an efficient method to propagate the radiation which does not suffer from the ray effect

  8. Morphological modeling of terrains and volume data

    CERN Document Server

    Comic, Lidija; Magillo, Paola; Iuricich, Federico

    2014-01-01

    This book describes the mathematical background behind discrete approaches to morphological analysis of scalar fields, with a focus on Morse theory and on the discrete theories due to Banchoff and Forman. The algorithms and data structures presented are used for terrain modeling and analysis, molecular shape analysis, and for analysis or visualization of sensor and simulation 3D data sets. It covers a variety of application domains including geography, geology, environmental sciences, medicine and biology. The authors classify the different approaches to morphological analysis which are all ba

  9. A volume element model (VEM) for energy systems engineering

    OpenAIRE

    Dilay, Emerson; Vargas, Jose Viriato Coelho; Souza, Jeferson Avila; Ordonez, Juan Carlos; Yang, Sam; Mariano, André Bellin

    2015-01-01

    This work presents a simplified modeling and simulation approach for energy systems engineering that is capable of providing quick and accurate responses during system design. For that, the laws of conservation are combined with available empirical and theoretical correlations to quantify the diverse types of flows that cross the system and produce a simplified tridimensional mathematical model, namely a volume element model (VEM). The physical domain of interest is discretized in space, thus...

  10. A volume-balance model for flow on porous media

    Science.gov (United States)

    Malaga, Carlos; Mandujano, Francisco; Becerra, Julian

    2015-11-01

    Volume-balance models are used by petroleum engineers for simulating multiphase and multicomponent flow phenomena in porous media and the extraction process in oil reservoirs. In these models, mass conservation equations and Darcy's law are supplemented by a balance condition for the pore and fluid volumes. This provides a pressure equation suitable for simulating a compressible flow within a compressible solid matrix. Here we present an alternative interpretation of the volume-balance condition that includes the advective transport within a consolidated porous media. We obtain a modified equation for the time evolution of the pressure field. Numerical tests for phase separation under gravity are presented for multiphase three dimensional flow in heterogeneous porous media. The authors acknowledge funding from Fondo Sectorial CONACYT-SENER grant number 42536 (DGAJ-SPI-34-170412-217).

  11. Control volume based modelling of compressible flow in reciprocating machines

    DEFF Research Database (Denmark)

    Andersen, Stig Kildegård; Thomsen, Per Grove; Carlsen, Henrik

    2004-01-01

    conservation laws for mass, energy, and momentum applied to a staggered mesh consisting of two overlapping strings of control volumes. Loss mechanisms can be included directly in the governing equations of models by including them as terms in the conservation laws. Heat transfer, flow friction......, and multidimensional effects must be calculated using empirical correlations; correlations for steady state flow can be used as an approximation. A transformation that assumes ideal gas is presented for transforming equations for masses and energies in control volumes into the corresponding pressures and temperatures...

  12. Modeling of piezoelectric devices with the finite volume method.

    Science.gov (United States)

    Bolborici, Valentin; Dawson, Francis; Pugh, Mary

    2010-07-01

    A partial differential equation (PDE) model for the dynamics of a thin piezoelectric plate in an electric field is presented. This PDE model is discretized via the finite volume method (FVM), resulting in a system of coupled ordinary differential equations. A static analysis and an eigenfrequency analysis are done with results compared with those provided by a commercial finite element (FEM) package. We find that fewer degrees of freedom are needed with the FVM model to reach a specified degree of accuracy. This suggests that the FVM model, which also has the advantage of an intuitive interpretation in terms of electrical circuits, may be a better choice in control situations.

  13. Atomistic models of amorphous polybutadienes; 3 -- Static free volume

    Energy Technology Data Exchange (ETDEWEB)

    Misra, S.; Mattice, W.L. [Univ. of Akron, OH (United States). Inst. of Polymer Science

    1993-12-20

    Atomistic models of polybutadiene have been generated using molecular mechanics and molecular dynamics at a bulk density of 0.89 g cm{sup {minus}3}. Four microstructures formed by cis-1,4-polybutadiene, trans-1,4-polybutadiene, 1,2-polybutadiene, and a random copolymer of the three (55% trans, 35% cis, and 10% vinyl) are analyzed for static free volume. The free volume is determined by hard spherical probes that see the atoms as hard spheres of radii which equal 89% of their van der Waals radii. The total free volume, the free volume distribution, and the shape of the voids are analyzed for all four microstructures. The accessible free volume as a function of the probe size is found to be characteristic of voids in disordered packings of hard spheres. The free volume distributions have some common features across the microstructures. In particular, the free volume distributions as probed by a 1-{angstrom} radius probe show void size concentrations around {approximately}7.5 and 15 {angstrom}{sup 3} (with the exception of trans-polybutadiene, which does not display the latter). The shape factors for all four structures decay to the same asymptotic value of 0.67 {+-} 0.1 over the size range of 0--5 {angstrom}{sup 3}. There is a marked difference in the asphericity and the acylindricity of voids in the four microstructures. Analysis of randomly generated shapes suggests that the voids in the polymer microstructures are mostly elongated in comparison with randomly ``grown`` cavities, probably due to the connectivity of the polymer chains.

  14. Model documentation: Natural Gas Transmission and Distribution Model of the National Energy Modeling System; Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-02-24

    The Natural Gas Transmission and Distribution Model (NGTDM) is a component of the National Energy Modeling System (NEMS) used to represent the domestic natural gas transmission and distribution system. NEMS is the third in a series of computer-based, midterm energy modeling systems used since 1974 by the Energy Information Administration (EIA) and its predecessor, the Federal Energy Administration, to analyze domestic energy-economy markets and develop projections. This report documents the archived version of NGTDM that was used to produce the natural gas forecasts used in support of the Annual Energy Outlook 1994, DOE/EIA-0383(94). The purpose of this report is to provide a reference document for model analysts, users, and the public that defines the objectives of the model, describes its basic design, provides detail on the methodology employed, and describes the model inputs, outputs, and key assumptions. It is intended to fulfill the legal obligation of the EIA to provide adequate documentation in support of its models (Public Law 94-385, Section 57.b.2). This report represents Volume 1 of a two-volume set. (Volume 2 will report on model performance, detailing convergence criteria and properties, results of sensitivity testing, comparison of model outputs with the literature and/or other model results, and major unresolved issues.) Subsequent chapters of this report provide: (1) an overview of the NGTDM (Chapter 2); (2) a description of the interface between the National Energy Modeling System (NEMS) and the NGTDM (Chapter 3); (3) an overview of the solution methodology of the NGTDM (Chapter 4); (4) the solution methodology for the Annual Flow Module (Chapter 5); (5) the solution methodology for the Distributor Tariff Module (Chapter 6); (6) the solution methodology for the Capacity Expansion Module (Chapter 7); (7) the solution methodology for the Pipeline Tariff Module (Chapter 8); and (8) a description of model assumptions, inputs, and outputs (Chapter 9).

  15. MODEL PERUBAHAN VOLUME KERIPIK BUAH SELAMA PROSES PENGGORENGAN SECARA VAKUM [Model for Volume Changes in Fruit Chips during Vacuum Frying

    Directory of Open Access Journals (Sweden)

    Jamaluddin1*

    2011-06-01

    Full Text Available Expansion and puffing are specific characteristics of fried products critical for consumer preferences. To obtain expanded and puffed dried products that fit well with consumer acceptance criteria, it is necessary to pay attention to the process conditions which change the raw material characteristics during frying. The important changes include volume and density ratio of the products during frying. Hypothetically, these changes are due to water vaporization and the decrease dry matter in the products. The objective of this research is to develop a mathematical model of volume and density ratio changes for jack fruit during vacuum frying as a function of water and starch content reductions. Samples were vacuum fried at 70–100OC and pressure of 80-90 kPa for 15–60 min. The parameters observed were volume and density as well as water and starch contents of samples before and after vacuum frying. The results showed that the developed model can be used to predict changes in volume and density ratio of jack fruit during vacuum frying.

  16. Modelling and Simulation of Volume Controlled Mechanical Ventilation System

    Directory of Open Access Journals (Sweden)

    Yan Shi

    2014-01-01

    Full Text Available Volume controlled mechanical ventilation system is a typical time-delay system, which is applied to ventilate patients who cannot breathe adequately on their own. To illustrate the influences of key parameters of the ventilator on the dynamics of the ventilated respiratory system, this paper firstly derived a new mathematical model of the ventilation system; secondly, simulation and experimental results are compared to verify the mathematical model; lastly, the influences of key parameters of ventilator on the dynamics of the ventilated respiratory system are carried out. This study can be helpful in the VCV ventilation treatment and respiratory diagnostics.

  17. Development of modelling and forecasting in geology. (Volume 2)

    International Nuclear Information System (INIS)

    Seguin, J.J.; Fourniguet, J.; Peaudecerf, P.

    1990-01-01

    To access the long-term safety of radioactive waste disposal systems, validation of predictive models is essential and large efforts should be given to barriers, particularly geologic barriers. This work appears in the form of four volumes, the subject of the second part is described below. HERODE (calculation of relief altitude under erosion process from 0 to 100000 years) is a weathering and erosion computerized simulation. The model describes materials and rocks transport and also substratum weathering process. FORTRAN 77 is the software language. 31 figs., 6 tabs., 40 refs

  18. Comparison of Statistically Modeled Contaminated Soil Volume Estimates and Actual Excavation Volumes at the Maywood FUSRAP Site - 13555

    International Nuclear Information System (INIS)

    Moore, James; Hays, David; Quinn, John; Johnson, Robert; Durham, Lisa

    2013-01-01

    As part of the ongoing remediation process at the Maywood Formerly Utilized Sites Remedial Action Program (FUSRAP) properties, Argonne National Laboratory (Argonne) assisted the U.S. Army Corps of Engineers (USACE) New York District by providing contaminated soil volume estimates for the main site area, much of which is fully or partially remediated. As part of the volume estimation process, an initial conceptual site model (ICSM) was prepared for the entire site that captured existing information (with the exception of soil sampling results) pertinent to the possible location of surface and subsurface contamination above cleanup requirements. This ICSM was based on historical anecdotal information, aerial photographs, and the logs from several hundred soil cores that identified the depth of fill material and the depth to bedrock under the site. Specialized geostatistical software developed by Argonne was used to update the ICSM with historical sampling results and down-hole gamma survey information for hundreds of soil core locations. The updating process yielded both a best guess estimate of contamination volumes and a conservative upper bound on the volume estimate that reflected the estimate's uncertainty. Comparison of model results to actual removed soil volumes was conducted on a parcel-by-parcel basis. Where sampling data density was adequate, the actual volume matched the model's average or best guess results. Where contamination was un-characterized and unknown to the model, the actual volume exceeded the model's conservative estimate. Factors affecting volume estimation were identified to assist in planning further excavations. (authors)

  19. Modeling of deformation phenomena in volume label during its operation

    Directory of Open Access Journals (Sweden)

    Svitlana Sheludko

    2017-06-01

    Full Text Available BIt was considered in the article the research of physical and mechanical properties of materials based on PVC film ORACAL and RITRAMA that used in the production of volume labels. In particular, it was shown the changes of dependences between linear deformation of printed and unprinted films and the value of stress with regard to their minimum and maximum values. It was also established that deformation properties of the films are different in the transverse and longitudinal directions, which should be considered when producing labels. It was conducted the modeling of stress-strain state of volume label when gluing it to the surfaces of various shapes. We considered the boundary conditions for displacement and stress of labels layer components with regard to the chemical structure of epoxy resins and their physical and mechanical characteristics.

  20. EPR-based material modelling of soils considering volume changes

    Science.gov (United States)

    Faramarzi, Asaad; Javadi, Akbar A.; Alani, Amir M.

    2012-11-01

    In this paper an approach is presented for developing material models for soils based on evolutionary polynomial regression (EPR), taking into account its volumetric behaviour. EPR is a recently developed hybrid data mining technique that searches for structured mathematical equations (representing the behaviour of a system) using genetic algorithm and the least squares method. Stress-strain data from triaxial test are used to train and develop EPR-based material models for soil. The developed models are compared with some of the well known conventional material models. In particular, the capability of the developed EPR models in predicting volume change behaviour of soils is illustrated. It is also shown that the developed EPR-based material models can be incorporated in finite element (FE) analysis. Two geotechnical examples are presented to verify the developed EPR-based FE model (EPR-FEM). The results of the EPR-FEM are compared with those of a standard FEM where conventional constitutive models are used to describe the material behaviour. The results show that EPR-FEM can be successfully employed to analyse geotechnical engineering problems. The advantages of the proposed EPR models are highlighted.

  1. Analysis of modeling cumulative noise from simultaneous flights volume 1 : analysis at four national parks

    Science.gov (United States)

    2012-12-31

    This is the first of two volumes of the report on modeling cumulative noise from simultaneous flights. This volume includes: an overview of the time compression algorithms used to model simultaneous aircraft; revised summary of a preliminary study (w...

  2. Assessment of the hybrid propagation model, Volume 1: Analysis of noise propagation effects

    Science.gov (United States)

    2012-08-31

    This is the first of two volumes of a report on the Hybrid Propagation Model (HPM), an advanced prediction model for aviation noise propagation. This volume presents the noise level predictions for eleven different sets of propagation conditions, run...

  3. Modeling of Cementitious Representative Volume Element with Additives

    Science.gov (United States)

    Shahzamanian, M. M.; Basirun, W. J.

    CEMHYD3D has been employed to simulate the representative volume element (RVE) of cementitious systems (Type I cement) containing fly ash (Class F) through a voxel-based finite element analysis (FEA) approach. Three-dimensional microstructures composed of voxels are generated for a heterogeneous cementitious material consisting of various constituent phases. The primary focus is to simulate a cementitious RVE containing fly ash and to present the homogenized macromechanical properties obtained from its analysis. Simple kinematic uniform boundary conditions as well as periodic boundary conditions were imposed on the RVE to obtain the principal and shear moduli. Our current work considers the effect of fly ash percentage on the elastic properties based on the mass and volume replacements. RVEs with lengths of 50, 100 and 200μm at different degrees of hydration are generated, and the elastic properties are modeled and simulated. In general, the elastic properties of a cementitious RVE with fly ash replacement for cement based on mass and volume differ from each other. Moreover, the finite element (FE) mesh density effect is studied. Results indicate that mechanical properties decrease with increasing mesh density.

  4. Homogenization in the Modelling of Volume-Controlled Elastic Structures

    International Nuclear Information System (INIS)

    Russell, David L.

    2007-01-01

    The background for this article is the question of modification of the geometric configuration of an elastic structure by means of 'volume'-type actuation. In this actuation mode stresses are applied to the elastic body by injection/extraction of a fluid into, or from, a large number of vacuoles in the elastic 'matrix' material. Previous articles by the author, and others, have examined this process and studied its effectiveness in the context of a 'naive' continuous model. The present paper develops modified models in the two-dimensional case by applying the 'multiple scales' homogenization method to elastic bodies with increasingly small and numerous vacuoles arranged in a rectangularly periodic structure. The process leads to a modification of the naive model potentially useful in future elastic system control research

  5. Volume Dynamics Propulsion System Modeling for Supersonics Vehicle Research

    Science.gov (United States)

    Kopasakis, George; Connolly, Joseph W.; Paxson, Daniel E.; Ma, Peter

    2010-01-01

    Under the NASA Fundamental Aeronautics Program the Supersonics Project is working to overcome the obstacles to supersonic commercial flight. The proposed vehicles are long slim body aircraft with pronounced aero-servo-elastic modes. These modes can potentially couple with propulsion system dynamics; leading to performance challenges such as aircraft ride quality and stability. Other disturbances upstream of the engine generated from atmospheric wind gusts, angle of attack, and yaw can have similar effects. In addition, for optimal propulsion system performance, normal inlet-engine operations are required to be closer to compressor stall and inlet unstart. To study these phenomena an integrated model is needed that includes both airframe structural dynamics as well as the propulsion system dynamics. This paper covers the propulsion system component volume dynamics modeling of a turbojet engine that will be used for an integrated vehicle Aero-Propulso-Servo-Elastic model and for propulsion efficiency studies.

  6. Integrating model of the Project Independence Evaluation System. Volume IV. Model documentation

    Energy Technology Data Exchange (ETDEWEB)

    Shaw, M L; Allen, B J; Gale, J E; Lutz, M S; O& #x27; Hara, N E; Wood, R K

    1979-02-01

    This volume is the fourth in a series of seven documenting the PIES Integrating Model. It contains detailed descriptions of the basic assumptions behind each of the components of PIES and how they interact with one another. Chapter II of this volume presents the methodology used to integrate supply and demand. It includes a discussion of both the interface between the Demand Model and the equilibrating mechanism and the various supply models via the equilibrating algorithm used by PIES. Chapters III through IX describe each supply submodel in turn: coal, oil, and natural gas supply, utilities, refineries, advanced technologies, and transportation. Code and data documentation are covered elsewhere in this series (Volumes V and VI respectively). PIES is an evolving system. As this document was being prepared, many parts of the model were being modified. This document describes the PIES Integrating Model as of January 1, 1978.

  7. Development of modelling and forecasting in geology (Volume 4)

    International Nuclear Information System (INIS)

    Courbouleix, S.; Colleau, A.; Defaut, B.; Fourniguet, J.; Peaudecerf, P.

    1990-01-01

    To access the long-term safety of radioactive waste disposal systems, validation of predictive models is essential and large efforts should be given to barriers, particularly geologic barriers. This work appears in the form of four volumes, the subject of the fourth part is described below. The purpose of this study is to find actual climates which can represent past climates in Europe, during Plio-Quaternary Palynology technics is the most adapted to restore ancient climates. A climatic index, Q n is defined as a function of yearly rainfalls, monthly extreme temperatures and aridity. A climatic diagram is built with climatic index Q n along X axis and a function of the yearly mean temperature along Y axis. This original method can ensure vegetation determination from climate and vice versa. Erosion and Weathering values may be determined after model calibration. 23 figs., 21 refs

  8. Fixed site neutralization model programmer's manual. Volume 1

    International Nuclear Information System (INIS)

    Engi, D.; Chapman, L.; Judnick, W.; Blum, R.; Broegler, L.; Lenz, J.; Weinthraub, A.; Ballard, D.

    1979-12-01

    The Fixed Site Neutralization Model (FSNM) is a stochastic, time-stepped simulation of an engagement process whereby an adversary force attempts to steal or sabotage sensitive (e.g., nuclear) materials being guarded by a security force on a fixed site and a response force that is off-site. FSNM will assist regulatory bodies of the US Government in evaluating fixed site physical protection systems at various installations in a variety of scenarios. Most data input to the Fixed Site Neutralization Model are in binary form. The user's data are transformed into binary form by two supporting modules, the Data Preprocessor (DPP) and the Plex Preprocessor (PPP). Both preprocessors and the FSNM itself are written in FORTRAN. This volume of the program maintenance program contains: introduction, logic descriptions, PLEX data structure, PLEX records, dictionaries, and error conditions and comments

  9. Volume conductor model of transcutaneous electrical stimulation with kilohertz signals

    Science.gov (United States)

    Medina, Leonel E.; Grill, Warren M.

    2014-12-01

    Objective. Incorporating high-frequency components in transcutaneous electrical stimulation (TES) waveforms may make it possible to stimulate deeper nerve fibers since the impedance of tissue declines with increasing frequency. However, the mechanisms of high-frequency TES remain largely unexplored. We investigated the properties of TES with frequencies beyond those typically used in neural stimulation. Approach. We implemented a multilayer volume conductor model including dispersion and capacitive effects, coupled to a cable model of a nerve fiber. We simulated voltage- and current-controlled transcutaneous stimulation, and quantified the effects of frequency on the distribution of potentials and fiber excitation. We also quantified the effects of a novel transdermal amplitude modulated signal (TAMS) consisting of a non-zero offset sinusoidal carrier modulated by a square-pulse train. Main results. The model revealed that high-frequency signals generated larger potentials at depth than did low frequencies, but this did not translate into lower stimulation thresholds. Both TAMS and conventional rectangular pulses activated more superficial fibers in addition to the deeper, target fibers, and at no frequency did we observe an inversion of the strength-distance relationship. Current regulated stimulation was more strongly influenced by fiber depth, whereas voltage regulated stimulation was more strongly influenced by skin thickness. Finally, our model reproduced the threshold-frequency relationship of experimentally measured motor thresholds. Significance. The model may be used for prediction of motor thresholds in TES, and contributes to the understanding of high-frequency TES.

  10. INTRA/Mod3.2. Manual and Code Description. Volume I - Physical Modelling

    Energy Technology Data Exchange (ETDEWEB)

    Andersson, Jenny; Edlund, O.; Hermann, J.; Johansson, Lise-Lotte

    1999-01-01

    The INTRA Manual consists of two volumes. Volume I of the manual is a thorough description of the code INTRA, the Physical modelling of INTRA and the ruling numerical methods and volume II, the User`s Manual is an input description. This document, the Physical modelling of INTRA, contains code characteristics, integration methods and applications

  11. Models for estimation of tree volume in the miombo woodlands of ...

    African Journals Online (AJOL)

    Volume of trees is an important parameter in forest management, but only volume models with limited geographical and tree size coverage have previously been developed for Tanzanian miombo woodlands. This study developed models for estimating total, merchantable stem and branches volume applicable for the entire ...

  12. Development of modelling and forecasting in geology. (Volume 1)

    International Nuclear Information System (INIS)

    Afzali, H.; Fourniguet, J.; Peaudecerf, P.

    1990-01-01

    To assess the long-term safety of radioactive waste disposal systems, validation of predictive models is essential and large efforts should be given to barriers, particularly geologic barriers. This work appears in the form of four volumes, the subject of the first part is described below. Soils and rocks erosion depends upon climate, relief, lithology and human activities (deforesting). In the world, mechanical erosion is evaluated from 5 to 8 cm per 1000 years (mean denudation ratio). Rocks weathering solubilize chemical elements in the running water and rocks fracturation becomes more easily under erosion effects. Alteration front progress is 0.3-3 cm per 1000 years in temperate zones and 4-7 cm per 1000 years in tropical zones. 5 figs., 14 tabs., 80 refs

  13. Ammunition Resupply Model. Volume 2. Programmer’s Manual.

    Science.gov (United States)

    1983-05-01

    database for the ARM model (see volume I for the array definitions): COMMON/LOG/IATP(lO,53), IASP (lO,lIO), IUNIT(75,142), Z ITRUCK(1400,15), ITYPE(9,6), IMIX...from either the ATP or the ASP. C NASP The ASP number from the IASP array. (..6) C NATP The ATP rumber from the IATP array. (1..6) C ND ) The number of...TTLOAD C**Z2 DECREMENT AMMO AVAILABLE SO0 CONTINUE IASP (NASP9NUMAM*37+1B) = IASP (NASPYNUMAMt3+19) - MIX(MIXPNUMAM) IF7IASP(NASPiNUMAHM*3+1S).LT, 0

  14. Alligator Rivers Analogue project. Hydrogeological modelling. Final Report - Volume 6

    Energy Technology Data Exchange (ETDEWEB)

    Townley, L.R.; Trefry, M.G.; Barr, A.D. [CSIRO Div of Water Resources, PO Wembley, WA (Australia); Braumiller, S. [Univ of Arizona, Tucson, AZ (United States). Dept of Hydrology and Water Resources; Kawanishi, M. [Central Research Institute of Electric Power Industry, Abiko-Shi, Chiba-Ken (Japan)] [and others

    1992-12-31

    This volume describes hydrogeological modelling carried out as part of the Alligator Rivers Analogue Project. Hydrogeology has played a key integrating role in the Project, largely because water movement is believed to have controlled the evolution of the Koongarra uranium Orebody and therefore affects field observations of all types at all scales. Aquifer testing described uses the concept of transmissivity in its interpretation of aquifer response to pumping. The concept of an aquifer, a layer transmitting significant quantities of water in a mainly horizontal direction, seems hard to accept in an environment as heterogeneous as that at Koongarra. But modelling of aquifers both in one dimension and two dimensionally in plan has contributed significantly to our understanding of the site. A one-dimensional model with three layers (often described as a quasi two dimensional model) was applied to flow between the Fault and Koongarra Creek. Being a transient model, this model was able to show that reverse flows can indeed occur back towards the Fault, but only if there is distributed recharge over the orebody as well as a mechanism for the Fault, or a region near the Fault, to remove water from the simulated cross-section. The model also showed clearly that the response of the three-layered system, consisting of a highly weathered zone, a fractured transmissive zone and a less conductive lower schist zone, is governed mainly by the transmissivity and storage coefficient of the middle layer. The storage coefficient of the higher layer has little effect. A two-dimensional model in plan used a description of anisotropy to show that reverse flows can also occur even without a conducting Fault. Modelling of a three-dimensional region using discrete fractures showed that it is certainly possible to simulate systems like that observed at Koongarra, but that large amounts of data are probably needed to obtain realistic descriptions of the fracture networks. Inverse modelling

  15. Alligator Rivers Analogue project. Hydrogeological modelling. Final Report - Volume 6

    International Nuclear Information System (INIS)

    Townley, L.R.; Trefry, M.G.; Barr, A.D.; Braumiller, S.

    1992-01-01

    This volume describes hydrogeological modelling carried out as part of the Alligator Rivers Analogue Project. Hydrogeology has played a key integrating role in the Project, largely because water movement is believed to have controlled the evolution of the Koongarra uranium Orebody and therefore affects field observations of all types at all scales. Aquifer testing described uses the concept of transmissivity in its interpretation of aquifer response to pumping. The concept of an aquifer, a layer transmitting significant quantities of water in a mainly horizontal direction, seems hard to accept in an environment as heterogeneous as that at Koongarra. But modelling of aquifers both in one dimension and two dimensionally in plan has contributed significantly to our understanding of the site. A one-dimensional model with three layers (often described as a quasi two dimensional model) was applied to flow between the Fault and Koongarra Creek. Being a transient model, this model was able to show that reverse flows can indeed occur back towards the Fault, but only if there is distributed recharge over the orebody as well as a mechanism for the Fault, or a region near the Fault, to remove water from the simulated cross-section. The model also showed clearly that the response of the three-layered system, consisting of a highly weathered zone, a fractured transmissive zone and a less conductive lower schist zone, is governed mainly by the transmissivity and storage coefficient of the middle layer. The storage coefficient of the higher layer has little effect. A two-dimensional model in plan used a description of anisotropy to show that reverse flows can also occur even without a conducting Fault. Modelling of a three-dimensional region using discrete fractures showed that it is certainly possible to simulate systems like that observed at Koongarra, but that large amounts of data are probably needed to obtain realistic descriptions of the fracture networks. Inverse modelling

  16. Modeled Urea Distribution Volume and Mortality in the HEMO Study

    Science.gov (United States)

    Greene, Tom; Depner, Thomas A.; Levin, Nathan W.; Chertow, Glenn M.

    2011-01-01

    Summary Background and objectives In the Hemodialysis (HEMO) Study, observed small decreases in achieved equilibrated Kt/Vurea were noncausally associated with markedly increased mortality. Here we examine the association of mortality with modeled volume (Vm), the denominator of equilibrated Kt/Vurea. Design, setting, participants, & measurements Parameters derived from modeled urea kinetics (including Vm) and blood pressure (BP) were obtained monthly in 1846 patients. Case mix–adjusted time-dependent Cox regressions were used to relate the relative mortality hazard at each time point to Vm and to the change in Vm over the preceding 6 months. Mixed effects models were used to relate Vm to changes in intradialytic systolic BP and to other factors at each follow-up visit. Results Mortality was associated with Vm and change in Vm over the preceding 6 months. The association between change in Vm and mortality was independent of vascular access complications. In contrast, mortality was inversely associated with V calculated from anthropometric measurements (Vant). In case mix–adjusted analysis using Vm as a time-dependent covariate, the association of mortality with Vm strengthened after statistical adjustment for Vant. After adjustment for Vant, higher Vm was associated with slightly smaller reductions in intradialytic systolic BP and with risk factors for mortality including recent hospitalization and reductions in serum albumin concentration and body weight. Conclusions An increase in Vm is a marker for illness and mortality risk in hemodialysis patients. PMID:21511841

  17. Transportation Sector Model of the National Energy Modeling System. Volume 2 -- Appendices: Part 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-01-01

    This volume contains input data and parameters used in the model of the transportation sector of the National Energy Modeling System. The list of Transportation Sector Model variables includes parameters for the following: Light duty vehicle modules (fuel economy, regional sales, alternative fuel vehicles); Light duty vehicle stock modules; Light duty vehicle fleet module; Air travel module (demand model and fleet efficiency model); Freight transport module; Miscellaneous energy demand module; and Transportation emissions module. Also included in these appendices are: Light duty vehicle market classes; Maximum light duty vehicle market penetration parameters; Aircraft fleet efficiency model adjustment factors; and List of expected aircraft technology improvements.

  18. Theoretical modeling of molar volume and thermal expansion

    Energy Technology Data Exchange (ETDEWEB)

    Lu Xiaogang [Department of Materials Science and Engineering, Royal Institute of Technology, 100 44 Stockholm (Sweden)]. E-mail: gang@mse.kth.se; Selleby, Malin [Department of Materials Science and Engineering, Royal Institute of Technology, 100 44 Stockholm (Sweden); Sundman, Bo [Department of Materials Science and Engineering, Royal Institute of Technology, 100 44 Stockholm (Sweden)

    2005-05-15

    The molar volumes and thermal expansions of transition cubic metals were studied by means of the Calphad approach and the Debye-Grueneisen model. Experimental data were collected and assessed using Calphad procedures, and consistent results were obtained which give the best description of all experimental data. In order to put the prediction of the thermodynamic properties of metastable phases on a sound physical basis, the Debye-Grueneisen model was chosen to account for the vibrational contribution and calculate the coefficients of linear thermal expansion (CLEs) of stable cubic metals. Two approximations for Grueneisen parameter {gamma}, i.e. Slater's and Dugdale and MacDonald's expressions were adopted. A modified calculation scheme, first proposed by Wang et al., was derived in a straightforward way and used to evaluate the Debye temperature from ab initio electronic total-energy calculations at T = 0 K. The thermal electronic contribution to CLE was also evaluated from the electronic density of states. The calculated total CLEs were compared with those from the Calphad assessments. A satisfactory agreement is reached.

  19. Theoretical modeling of molar volume and thermal expansion

    International Nuclear Information System (INIS)

    Lu Xiaogang; Selleby, Malin; Sundman, Bo

    2005-01-01

    The molar volumes and thermal expansions of transition cubic metals were studied by means of the Calphad approach and the Debye-Grueneisen model. Experimental data were collected and assessed using Calphad procedures, and consistent results were obtained which give the best description of all experimental data. In order to put the prediction of the thermodynamic properties of metastable phases on a sound physical basis, the Debye-Grueneisen model was chosen to account for the vibrational contribution and calculate the coefficients of linear thermal expansion (CLEs) of stable cubic metals. Two approximations for Grueneisen parameter γ, i.e. Slater's and Dugdale and MacDonald's expressions were adopted. A modified calculation scheme, first proposed by Wang et al., was derived in a straightforward way and used to evaluate the Debye temperature from ab initio electronic total-energy calculations at T = 0 K. The thermal electronic contribution to CLE was also evaluated from the electronic density of states. The calculated total CLEs were compared with those from the Calphad assessments. A satisfactory agreement is reached

  20. Simple, Inexpensive Model Spirometer for Understanding Ventilation Volumes

    Science.gov (United States)

    Giuliodori, Mauricio J.; DiCarlo, Stephen E.

    2004-01-01

    Spirometers are useful for enhancing students' understanding of normal lung volumes, capacities, and flow rates. Spirometers are also excellent for understanding how lung diseases alter ventilation volumes. However, spirometers are expensive, complex, and not appropriate for programs with limited space and budgets. Therefore, we developed a…

  1. Development and validation of stem volume models for Pinus kesiya ...

    African Journals Online (AJOL)

    Stem volume equations (overbark) were developed, using established volume equation forms, and validated using a subset of the data collected for Pinus kesiya in Benguet province, Philippines. A total of 481 trees from Pinus kesiya stands in Benguet were measured through non-destructive sampling. The data set was ...

  2. Stem biomass and volume models of selected tropical tree species ...

    African Journals Online (AJOL)

    Estimating tree volume and biomass constitutes an essential part of the forest resources assessment and the evaluation of the climate change mitigation potential of forests through biomass accumulation and carbon sequestration. This research article provides stem volume and biomass equations applicable to five tree ...

  3. Partial molar volume of proteins studied by the three-dimensional reference interaction site model theory.

    Science.gov (United States)

    Imai, Takashi; Kovalenko, Andriy; Hirata, Fumio

    2005-04-14

    The three-dimensional reference interaction site model (3D-RISM) theory is applied to the analysis of hydration effects on the partial molar volume of proteins. For the native structure of some proteins, the partial molar volume is decomposed into geometric and hydration contributions using the 3D-RISM theory combined with the geometric volume calculation. The hydration contributions are correlated with the surface properties of the protein. The thermal volume, which is the volume of voids around the protein induced by the thermal fluctuation of water molecules, is directly proportional to the accessible surface area of the protein. The interaction volume, which is the contribution of electrostatic interactions between the protein and water molecules, is apparently governed by the charged atomic groups on the protein surface. The polar atomic groups do not make any contribution to the interaction volume. The volume differences between low- and high-pressure structures of lysozyme are also analyzed by the present method.

  4. Uncertainty modelling and analysis of volume calculations based on a regular grid digital elevation model (DEM)

    Science.gov (United States)

    Li, Chang; Wang, Qing; Shi, Wenzhong; Zhao, Sisi

    2018-05-01

    The accuracy of earthwork calculations that compute terrain volume is critical to digital terrain analysis (DTA). The uncertainties in volume calculations (VCs) based on a DEM are primarily related to three factors: 1) model error (ME), which is caused by an adopted algorithm for a VC model, 2) discrete error (DE), which is usually caused by DEM resolution and terrain complexity, and 3) propagation error (PE), which is caused by the variables' error. Based on these factors, the uncertainty modelling and analysis of VCs based on a regular grid DEM are investigated in this paper. Especially, how to quantify the uncertainty of VCs is proposed by a confidence interval based on truncation error (TE). In the experiments, the trapezoidal double rule (TDR) and Simpson's double rule (SDR) were used to calculate volume, where the TE is the major ME, and six simulated regular grid DEMs with different terrain complexity and resolution (i.e. DE) were generated by a Gauss synthetic surface to easily obtain the theoretical true value and eliminate the interference of data errors. For PE, Monte-Carlo simulation techniques and spatial autocorrelation were used to represent DEM uncertainty. This study can enrich uncertainty modelling and analysis-related theories of geographic information science.

  5. Applying ARIMA model for annual volume time series of the Magdalena River

    Directory of Open Access Journals (Sweden)

    Gloria Amaris

    2017-04-01

    Conclusions: The simulated results obtained with the ARIMA model compared to the observed data showed a fairly good adjustment of the minimum and maximum magnitudes. This allows concluding that it is a good tool for estimating minimum and maximum volumes, even though this model is not capable of simulating the exact behaviour of an annual volume time series.

  6. Verification and transfer of thermal pollution model. Volume 5: Verification of 2-dimensional numerical model

    Science.gov (United States)

    Lee, S. S.; Sengupta, S.; Nwadike, E. V.

    1982-01-01

    The six-volume report: describes the theory of a three dimensional (3-D) mathematical thermal discharge model and a related one dimensional (1-D) model, includes model verification at two sites, and provides a separate user's manual for each model. The 3-D model has two forms: free surface and rigid lid. The former, verified at Anclote Anchorate (FL), allows a free air/water interface and is suited for significant surface wave heights compared to mean water depth; e.g., estuaries and coastal regions. The latter, verified at Lake Keowee (SC), is suited for small surface wave heights compared to depth (e.g., natural or man-made inland lakes) because surface elevation has been removed as a parameter. These models allow computation of time dependent velocity and temperature fields for given initial conditions and time-varying boundary conditions.

  7. An in vitro model of skeletal muscle volume regulation.

    Science.gov (United States)

    Wibberley, Anna; Staunton, Caroline A; Feetham, Claire H; Vereninov, Alexey A; Barrett-Jolley, Richard

    2015-01-01

    Hypertonic media causes cells to shrink due to water loss through aquaporin channels. After acute shrinkage, cells either regulate their volume or, alternatively, undergo a number of metabolic changes which ultimately lead to cell death. In many cell types, hypertonic shrinkage is followed by apoptosis. Due to the complex 3D morphology of skeletal muscle and the difficulty in obtaining isolated human tissue, we have begun skeletal muscle volume regulation studies using the human skeletal muscle cell line TE671RD. In this study we investigated whether hypertonic challenge of the human skeletal muscle cell line TE671RD triggered cell death or evoked a cell volume recovery response. The cellular volume of TE671RD cells was calculated from the 2D surface area. Cell death was assessed by both the trypan blue live/dead assay and the TUNEL assay. Medium osmolality was increased by addition of up to 200 mM sucrose. Addition of 200 mM sucrose resulted in mean cell shrinkage of 44±1% after 30 mins. At later time points (2 and 4 hrs) two separate cell subpopulations with differing mean cell volume became apparent. The first subpopulation (15±2% of the total cell number) continued to shrink whereas the second subpopulation had an increased cell volume. Cell death was observed in a small proportion of cells (approximately 6-8%). We have established that a substantial proportion of TE671RD cells respond to hypertonic challenge with RVI, but that these cells are resistant to hypertonicity triggered cell death.

  8. An in vitro model of skeletal muscle volume regulation.

    Directory of Open Access Journals (Sweden)

    Anna Wibberley

    Full Text Available Hypertonic media causes cells to shrink due to water loss through aquaporin channels. After acute shrinkage, cells either regulate their volume or, alternatively, undergo a number of metabolic changes which ultimately lead to cell death. In many cell types, hypertonic shrinkage is followed by apoptosis. Due to the complex 3D morphology of skeletal muscle and the difficulty in obtaining isolated human tissue, we have begun skeletal muscle volume regulation studies using the human skeletal muscle cell line TE671RD. In this study we investigated whether hypertonic challenge of the human skeletal muscle cell line TE671RD triggered cell death or evoked a cell volume recovery response.The cellular volume of TE671RD cells was calculated from the 2D surface area. Cell death was assessed by both the trypan blue live/dead assay and the TUNEL assay.Medium osmolality was increased by addition of up to 200 mM sucrose. Addition of 200 mM sucrose resulted in mean cell shrinkage of 44±1% after 30 mins. At later time points (2 and 4 hrs two separate cell subpopulations with differing mean cell volume became apparent. The first subpopulation (15±2% of the total cell number continued to shrink whereas the second subpopulation had an increased cell volume. Cell death was observed in a small proportion of cells (approximately 6-8%.We have established that a substantial proportion of TE671RD cells respond to hypertonic challenge with RVI, but that these cells are resistant to hypertonicity triggered cell death.

  9. Carbon footprint estimator, phase II : volume I - GASCAP model & volume II - technical appendices [technical brief].

    Science.gov (United States)

    2014-03-01

    This study resulted in the development of the GASCAP model (the Greenhouse Gas Assessment : Spreadsheet for Transportation Capital Projects). This spreadsheet model provides a user-friendly interface for determining the greenhouse gas (GHG) emissions...

  10. Verification and transfer of thermal pollution model. Volume 6: User's manual for 1-dimensional numerical model

    Science.gov (United States)

    Lee, S. S.; Sengupta, S.; Nwadike, E. V.

    1982-01-01

    The six-volume report: describes the theory of a three dimensional (3-D) mathematical thermal discharge model and a related one dimensional (1-D) model, includes model verification at two sites, and provides a separate user's manual for each model. The 3-D model has two forms: free surface and rigid lid. The former, verified at Anclote Anchorage (FL), allows a free air/water interface and is suited for significant surface wave heights compared to mean water depth; e.g., estuaries and coastal regions. The latter, verified at Lake Keowee (SC), is suited for small surface wave heights compared to depth (e.g., natural or man-made inland lakes) because surface elevation has been removed as a parameter.

  11. Transportation Sector Model of the National Energy Modeling System. Volume 2 -- Appendices: Part 3

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-01-01

    This Appendix consists of two unpublished reports produced by Energy and Environmental Analysis, Inc., under contract to Oak Ridge National Laboratory. These two reports formed the basis for the subsequent development of the Fuel Economy Model described in Volume 1. They are included in order to document more completely the efforts undertaken to construct a comprehensive model of automobile fuel economy. The supplemental reports are as follows: Supplement 1--Documentation Attributes of Technologies to Improve Automotive Fuel Economy; Supplement 2--Analysis of the Fuel Economy Boundary for 2010 and Comparison to Prototypes.

  12. Diameter structure modeling and the calculation of plantation volume of black poplar clones

    Directory of Open Access Journals (Sweden)

    Andrašev Siniša

    2004-01-01

    Full Text Available A method of diameter structure modeling was applied in the calculation of plantation (stand volume of two black poplar clones in the section Aigeiros (Duby: 618 (Lux and S1-8. Diameter structure modeling by Weibull function makes it possible to calculate the plantation volume by volume line. Based on the comparison of the proposed method with the existing methods, the obtained error of plantation volume was less than 2%. Diameter structure modeling and the calculation of plantation volume by diameter structure model, by the regularity of diameter distribution, enables a better analysis of the production level and assortment structure and it can be used in the construction of yield and increment tables.

  13. Electric field distribution in a finite-volume head model of deep brain stimulation

    OpenAIRE

    Grant, Peadar F.; Lowery, Madeleine M.

    2009-01-01

    This study presents a whole-head finite element model of deep brain stimulation to examine the effect of electrical grounding, the finite conducting volume of the head, and scalp, skull and cerebrospinal fluid layers. The impedance between the stimulating and reference electrodes in the whole-head model was found to lie within clinically reported values when the reference electrode was incorporated on a localized surface in the model. Incorporation of the finite volume of the head and inclusi...

  14. Transportation Sector Model of the National Energy Modeling System. Volume 2 -- Appendices: Part 2

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-01-01

    The attachments contained within this appendix provide additional details about the model development and estimation process which do not easily lend themselves to incorporation in the main body of the model documentation report. The information provided in these attachments is not integral to the understanding of the model`s operation, but provides the reader with opportunity to gain a deeper understanding of some of the model`s underlying assumptions. There will be a slight degree of replication of materials found elsewhere in the documentation, made unavoidable by the dictates of internal consistency. Each attachment is associated with a specific component of the transportation model; the presentation follows the same sequence of modules employed in Volume 1. The following attachments are contained in Appendix F: Fuel Economy Model (FEM)--provides a discussion of the FEM vehicle demand and performance by size class models; Alternative Fuel Vehicle (AFV) Model--describes data input sources and extrapolation methodologies; Light-Duty Vehicle (LDV) Stock Model--discusses the fuel economy gap estimation methodology; Light Duty Vehicle Fleet Model--presents the data development for business, utility, and government fleet vehicles; Light Commercial Truck Model--describes the stratification methodology and data sources employed in estimating the stock and performance of LCT`s; Air Travel Demand Model--presents the derivation of the demographic index, used to modify estimates of personal travel demand; and Airborne Emissions Model--describes the derivation of emissions factors used to associate transportation measures to levels of airborne emissions of several pollutants.

  15. Estimating tree bole volume using artificial neural network models for four species in Turkey.

    Science.gov (United States)

    Ozçelik, Ramazan; Diamantopoulou, Maria J; Brooks, John R; Wiant, Harry V

    2010-01-01

    Tree bole volumes of 89 Scots pine (Pinus sylvestris L.), 96 Brutian pine (Pinus brutia Ten.), 107 Cilicica fir (Abies cilicica Carr.) and 67 Cedar of Lebanon (Cedrus libani A. Rich.) trees were estimated using Artificial Neural Network (ANN) models. Neural networks offer a number of advantages including the ability to implicitly detect complex nonlinear relationships between input and output variables, which is very helpful in tree volume modeling. Two different neural network architectures were used and produced the Back propagation (BPANN) and the Cascade Correlation (CCANN) Artificial Neural Network models. In addition, tree bole volume estimates were compared to other established tree bole volume estimation techniques including the centroid method, taper equations, and existing standard volume tables. An overview of the features of ANNs and traditional methods is presented and the advantages and limitations of each one of them are discussed. For validation purposes, actual volumes were determined by aggregating the volumes of measured short sections (average 1 meter) of the tree bole using Smalian's formula. The results reported in this research suggest that the selected cascade correlation artificial neural network (CCANN) models are reliable for estimating the tree bole volume of the four examined tree species since they gave unbiased results and were superior to almost all methods in terms of error (%) expressed as the mean of the percentage errors. 2009 Elsevier Ltd. All rights reserved.

  16. Does amniotic fluid volume affect fetofetal transfusion in monochorionic twin pregnancies? Modelling two possible mechanisms

    NARCIS (Netherlands)

    Umur, Asli; van Gemert, Martin J. C.; Ross, Michael G.

    2002-01-01

    Clinical evidence suggests that increased amniotic fluid volume due to polyhydrarnnios increases placental vascular resistance. We have sought to model the possible effects of an increased amniotic fluid volume oil the net fetofetal transfusion in monochorionic twin pregnancies. We wanted to compare

  17. 1987 Oak Ridge model conference: Proceedings: Volume 3, Health and safety

    International Nuclear Information System (INIS)

    1987-01-01

    See the abstract for Volume I for general information on the conference. Topics discussed in Volume III include the use of models in handling hazardous materials, communication at waste sites, asbestos, regulatory decisions, emergency planning, training programs, occupational hazards, and protection of subcontractors

  18. Review of air quality modeling techniques. Volume 8

    International Nuclear Information System (INIS)

    Rosen, L.C.

    1977-01-01

    Air transport and diffusion models which are applicable to the assessment of the environmental effects of nuclear, geothermal, and fossil-fuel electric generation are reviewed. The general classification of models and model inputs are discussed. A detailed examination of the statistical, Gaussian plume, Gaussian puff, one-box and species-conservation-of-mass models is given. Representative models are discussed with attention given to the assumptions, input data requirement, advantages, disadvantages and applicability of each

  19. A general method for assessing the effects of uncertainty in individual-tree volume model predictions on large-area volume estimates with a subtropical forest illustration

    Science.gov (United States)

    Ronald E. McRoberts; Paolo Moser; Laio Zimermann Oliveira; Alexander C. Vibrans

    2015-01-01

    Forest inventory estimates of tree volume for large areas are typically calculated by adding the model predictions of volumes for individual trees at the plot level, calculating the mean over plots, and expressing the result on a per unit area basis. The uncertainty in the model predictions is generally ignored, with the result that the precision of the large-area...

  20. Calculation of search volume on cruise-searching planktivorous fish in foraging model.

    Science.gov (United States)

    Park, Bae Kyung; Lee, Yong Seok; Park, Seok Soon

    2007-07-01

    Search volume of cruising planktivorous fish was calculated based on its detailed behavior Th examine the factors influencing search volume, a series of experiments were conducted by varying ambient conditions, such as structural complexity light intensity and turbidity Pseudorasbora parva were used in experiment as predator and Daphnia pulex was selected as prey The shape of scanning area of P parva showed elliptic and the search volume changed drastically depending on ambient conditions. Compared with the results of previous foraging model, the search volumes of the fish under previous study were larger (1.2 to 2.4 times) than those from our study These results on the changes in feeding rate can be useful in determining microhabitat requirement of P parva and othercyprinids with a similar foraging behavior The calculated search volume is compared with other foraging model andthe effect of zooplankton-planktivore interactions on aquatic ecosystem is discussed.

  1. An enhanced matrix-free edge-based finite volume approach to model structures

    CSIR Research Space (South Africa)

    Suliman, Ridhwaan

    2010-01-01

    Full Text Available This paper presents the formulation, implementation and evaluation of an enhanced matrix free edge-based finite volume approach to model the mechanics of solids undergoing large non-linear deformations. The developed technology is evaluated via...

  2. Fixed site neutralization model programmer's manual. Volume II

    Energy Technology Data Exchange (ETDEWEB)

    Engi, D.; Chapman, L.D.; Judnick, W.; Blum, R.; Broegler, L.; Lenz, J.; Weinthraub, A.; Ballard, D.

    1979-12-01

    This report relates to protection of nuclear materials at nuclear facilities. This volume presents the source listings for the Fixed Site Neutralization Model and its supporting modules, the Plex Preprocessor and the Data Preprocessor. (DLC)

  3. HYDROCARBON SPILL SCREENING MODEL (HSSM) VOLUME 1: USER'S GUIDE

    Science.gov (United States)

    This users guide describes the Hydrocarbon Spill Screening Model (HSSM). The model is intended for simulation of subsurface releases of light nonaqueous phase liquids (LNAPLs). The model consists of separate modules for LNAPL flow through the vadose zone, spreading in the capil...

  4. Statistical Modeling of Ultrawideband Body-Centric Wireless Channels Considering Room Volume

    Directory of Open Access Journals (Sweden)

    Miyuki Hirose

    2012-01-01

    Full Text Available This paper presents the results of a statistical modeling of onbody ultrawideband (UWB radio channels for wireless body area network (WBAN applications. Measurements were conducted in five different rooms. A measured delay profile can be divided into two domains; in the first domain (04 ns has multipath components that are dominant and dependent on room volume. The first domain was modeled with a conventional power decay law model, and the second domain with a modified Saleh-Valenzuela model considering the room volume. Realizations of the impulse responses are presented based on the composite model and compared with the measured average power delay profiles.

  5. Underground Test Area Subproject Phase I Data Analysis Task. Volume VII - Tritium Transport Model Documentation Package

    Energy Technology Data Exchange (ETDEWEB)

    None

    1996-12-01

    Volume VII of the documentation for the Phase I Data Analysis Task performed in support of the current Regional Flow Model, Transport Model, and Risk Assessment for the Nevada Test Site Underground Test Area Subproject contains the tritium transport model documentation. Because of the size and complexity of the model area, a considerable quantity of data was collected and analyzed in support of the modeling efforts. The data analysis task was consequently broken into eight subtasks, and descriptions of each subtask's activities are contained in one of the eight volumes that comprise the Phase I Data Analysis Documentation.

  6. Stimulation model for lenticular sands: Volume 2, Users manual

    Energy Technology Data Exchange (ETDEWEB)

    Rybicki, E.F.; Luiskutty, C.T.; Sutrick, J.S.; Palmer, I.D.; Shah, G.H.; Tomutsa, L.

    1987-07-01

    This User's Manual contains information for four fracture/proppant models. TUPROP1 contains a Geertsma and de Klerk type fracture model. The section of the program utilizing the proppant fracture geometry data from the pseudo three-dimensional highly elongated fracture model is called TUPROPC. The analogous proppant section of the program that was modified to accept fracture shape data from SA3DFRAC is called TUPROPS. TUPROPS also includes fracture closure. Finally there is the penny fracture and its proppant model, PENNPROP. In the first three chapters, the proppant sections are based on the same theory for determining the proppant distribution but have modifications to support variable height fractures and modifications to accept fracture geometry from three different fracture models. Thus, information about each proppant model in the User's Manual builds on information supplied in the previous chapter. The exception to the development of combined treatment models is the penny fracture and its proppant model. In this case, a completely new proppant model was developed. A description of how to use the combined treatment model for the penny fracture is contained in Chapter 4. 2 refs.

  7. Predictor model for seasonal variations in skid resistance, volume 1

    Science.gov (United States)

    Henry, J. J.; Saito, K.; Blackburn, R.

    1984-04-01

    Two models, utilizing data collected in 1979 and 1980, were developed to predict variations in skid resistance due to rainfall conditions, temperature effects, and time of the year. A generalized predictor model was developed from purely statistical considerations and a mechanistic model was developed from hypothesized mechanisms. This model may be utilized to estimate the skid resistance at any time in the season from a measurement made during the same season, or to adjust skid-resistance measurement made at any time during the season to the end-of-season level. The mechanistic model requires, in addition to the above inputs, two pavement properties describing the polishing characteristics of the aggregate and an estimate of the percent normalized gradient of the skid resistance. The application of these models is summarized.

  8. Mesorad dose assessment model. Volume 1. Technical basis

    International Nuclear Information System (INIS)

    Scherpelz, R.I.; Bander, T.J.; Athey, G.F.; Ramsdell, J.V.

    1986-03-01

    MESORAD is a dose assessment model for emergency response applications. Using release data for as many as 50 radionuclides, the model calculates: (1) external doses resulting from exposure to radiation emitted by radionuclides contained in elevated or deposited material; (2) internal dose commitment resulting from inhalation; and (3) total whole-body doses. External doses from airborne material are calculated using semi-infinite and finite cloud approximations. At each stage in model execution, the appropriate approximation is selected after considering the cloud dimensions. Atmospheric processes are represented in MESORAD by a combination of Lagrangian puff and Gaussian plume dispersion models, a source depletion (deposition velocity) dry deposition model, and a wet deposition model using washout coefficients based on precipitation rates

  9. A model for vented deflagration of hydrogen in a volume

    International Nuclear Information System (INIS)

    Mulpuru, S.R.; Wilkin, G.B.

    1982-02-01

    A simple model was constructed to predict the property transients resulting from the deflagration of a combustible mixture in a sphere or cylinder with venting of the gas mixture to the environment. A computer program VENT, was written to solve the model equation. The model will be particularly useful for studying hydrogen burning effects in loss-of-coolant plus losss of emergency coolant accidents in CANDU reactors

  10. A Validated Normative Model for Human Uterine Volume from Birth to Age 40 Years.

    Science.gov (United States)

    Kelsey, Thomas W; Ginbey, Eleanor; Chowdhury, Moti M; Bath, Louise E; Anderson, Richard A; Wallace, W Hamish B

    2016-01-01

    Transabdominal pelvic ultrasound and/or pelvic Magnetic Resonance Imaging are safe, accurate and non-invasive means of determining the size and configuration of the internal female genitalia. The assessment of uterine size and volume is helpful in the assessment of many conditions including disorders of sex development, precocious or delayed puberty, infertility and menstrual disorders. Using our own data from the assessment of MRI scans in healthy young females and data extracted from four studies that assessed uterine volume using transabdominal ultrasound in healthy females we have derived and validated a normative model of uterine volume from birth to age 40 years. This shows that uterine volume increases across childhood, with a faster increase in adolescence reflecting the influence of puberty, followed by a slow but progressive rise during adult life. The model suggests that around 84% of the variation in uterine volumes in the healthy population up to age 40 is due to age alone. The derivation of a validated normative model for uterine volume from birth to age 40 years has important clinical applications by providing age-related reference values for uterine volume.

  11. Mechanistic Fluid Transport Model to Estimate Gastrointestinal Fluid Volume and Its Dynamic Change Over Time.

    Science.gov (United States)

    Yu, Alex; Jackson, Trachette; Tsume, Yasuhiro; Koenigsknecht, Mark; Wysocki, Jeffrey; Marciani, Luca; Amidon, Gordon L; Frances, Ann; Baker, Jason R; Hasler, William; Wen, Bo; Pai, Amit; Sun, Duxin

    2017-11-01

    Gastrointestinal (GI) fluid volume and its dynamic change are integral to study drug disintegration, dissolution, transit, and absorption. However, key questions regarding the local volume and its absorption, secretion, and transit remain unanswered. The dynamic fluid compartment absorption and transit (DFCAT) model is proposed to estimate in vivo GI volume and GI fluid transport based on magnetic resonance imaging (MRI) quantified fluid volume. The model was validated using GI local concentration of phenol red in human GI tract, which was directly measured by human GI intubation study after oral dosing of non-absorbable phenol red. The measured local GI concentration of phenol red ranged from 0.05 to 168 μg/mL (stomach), to 563 μg/mL (duodenum), to 202 μg/mL (proximal jejunum), and to 478 μg/mL (distal jejunum). The DFCAT model characterized observed MRI fluid volume and its dynamic changes from 275 to 46.5 mL in stomach (from 0 to 30 min) with mucus layer volume of 40 mL. The volumes of the 30 small intestine compartments were characterized by a max of 14.98 mL to a min of 0.26 mL (0-120 min) and a mucus layer volume of 5 mL per compartment. Regional fluid volumes over 0 to 120 min ranged from 5.6 to 20.38 mL in the proximal small intestine, 36.4 to 44.08 mL in distal small intestine, and from 42 to 64.46 mL in total small intestine. The DFCAT model can be applied to predict drug dissolution and absorption in the human GI tract with future improvements.

  12. A hybrid ARIMA and neural network model applied to forecast catch volumes of Selar crumenophthalmus

    Science.gov (United States)

    Aquino, Ronald L.; Alcantara, Nialle Loui Mar T.; Addawe, Rizavel C.

    2017-11-01

    The Selar crumenophthalmus with the English name big-eyed scad fish, locally known as matang-baka, is one of the fishes commonly caught along the waters of La Union, Philippines. The study deals with the forecasting of catch volumes of big-eyed scad fish for commercial consumption. The data used are quarterly caught volumes of big-eyed scad fish from 2002 to first quarter of 2017. This actual data is available from the open stat database published by the Philippine Statistics Authority (PSA)whose task is to collect, compiles, analyzes and publish information concerning different aspects of the Philippine setting. Autoregressive Integrated Moving Average (ARIMA) models, Artificial Neural Network (ANN) model and the Hybrid model consisting of ARIMA and ANN were developed to forecast catch volumes of big-eyed scad fish. Statistical errors such as Mean Absolute Errors (MAE) and Root Mean Square Errors (RMSE) were computed and compared to choose the most suitable model for forecasting the catch volume for the next few quarters. A comparison of the results of each model and corresponding statistical errors reveals that the hybrid model, ARIMA-ANN (2,1,2)(6:3:1), is the most suitable model to forecast the catch volumes of the big-eyed scad fish for the next few quarters.

  13. Measurement and modeling of advanced coal conversion processes, Volume II

    Energy Technology Data Exchange (ETDEWEB)

    Solomon, P.R.; Serio, M.A.; Hamblen, D.G. [and others

    1993-06-01

    A two dimensional, steady-state model for describing a variety of reactive and nonreactive flows, including pulverized coal combustion and gasification, is presented. The model, referred to as 93-PCGC-2 is applicable to cylindrical, axi-symmetric systems. Turbulence is accounted for in both the fluid mechanics equations and the combustion scheme. Radiation from gases, walls, and particles is taken into account using a discrete ordinates method. The particle phase is modeled in a lagrangian framework, such that mean paths of particle groups are followed. A new coal-general devolatilization submodel (FG-DVC) with coal swelling and char reactivity submodels has been added.

  14. Measurement and modeling of advanced coal conversion processes, Volume III

    Energy Technology Data Exchange (ETDEWEB)

    Ghani, M.U.; Hobbs, M.L.; Hamblen, D.G. [and others

    1993-08-01

    A generalized one-dimensional, heterogeneous, steady-state, fixed-bed model for coal gasification and combustion is presented. The model, FBED-1, is a design and analysis tool that can be used to simulate a variety of gasification, devolatilization, and combustion processes. The model considers separate gas and solid temperatures, axially variable solid and gas flow rates, variable bed void fraction, coal drying, devolatilization based on chemical functional group composition, depolymerization, vaporization and crosslinking, oxidation, and gasification of char, and partial equilibrium in the gas phase.

  15. Operational Modelling of the Aerospace Propagation Environment. Volume II

    Science.gov (United States)

    1978-11-01

    radiative transfer models are rarely available in a battlefield environment. tnly secondary ECNET parameters may be available. Hence, current modeling and...adopthe done lee traitements a 6tA de remplacer chaque valeur X4Dar son rang. Clest-h-diro quo Zj eet rermplacO pax Is nombre d’dohant~illons do X. qui...out uslub r -aItistial model relevant to thobe arcac If the Urt chooses a terraln typ- from the lIs- glvtn ,hov, a stetistlcol ’irregulal terr .’n

  16. Volume and aboveground biomass models for dry Miombo woodland in Tanzania

    DEFF Research Database (Denmark)

    Mwakalukwa, Ezekiel Edward; Meilby, Henrik; Treue, Thorsten

    2014-01-01

    Tools to accurately estimate tree volume and biomass are scarce for most forest types in East Africa, including Tanzania. Based on a sample of 142 trees and 57 shrubs from a 6,065 ha area of dry miombo woodland in Iringa rural district in Tanzania, regression models were developed for volume...... and biomass of three important species, Brachystegia spiciformis Benth. (n=40), Combretum molle G. Don (n=41), and Dalbergia arbutifolia Baker (n=37) separately, and for broader samples of trees (28 species, n=72), shrubs (16 species, n=31), and trees and shrubs combined (44 species, n=104). Applied...... of the predictions tended to increase from general to species-specific models. Except for a few volume and biomass models developed for shrubs, all models had R2 values of 96–99%. Thus, the models appear robust and should be applicable to forests with similar site conditions, species, and diameter ranges....

  17. Carbon footprint estimator, phase II : volume I - GASCAP model.

    Science.gov (United States)

    2014-03-01

    The GASCAP model was developed to provide a software tool for analysis of the life-cycle GHG : emissions associated with the construction and maintenance of transportation projects. This phase : of development included techniques for estimating emiss...

  18. Allometric Models for Estimating Tree Volume and Aboveground Biomass in Lowland Forests of Tanzania

    Directory of Open Access Journals (Sweden)

    Wilson Ancelm Mugasha

    2016-01-01

    Full Text Available Models to assist management of lowland forests in Tanzania are in most cases lacking. Using a sample of 60 trees which were destructively harvested from both dry and wet lowland forests of Dindili in Morogoro Region (30 trees and Rondo in Lindi Region (30 trees, respectively, this study developed site specific and general models for estimating total tree volume and aboveground biomass. Specifically the study developed (i height-diameter (ht-dbh models for trees found in the two sites, (ii total, merchantable, and branches volume models, and (iii total and sectional aboveground biomass models of trees found in the two study sites. The findings show that site specific ht-dbh model appears to be suitable in estimating tree height since the tree allometry was found to differ significantly between studied forests. The developed general volume models yielded unbiased mean prediction error and hence can adequately be applied to estimate tree volume in dry and wet lowland forests in Tanzania. General aboveground biomass model appears to yield biased estimates; hence, it is not suitable when accurate results are required. In this case, site specific biomass allometric models are recommended. Biomass allometric models which include basic wood density are highly recommended for improved estimates accuracy when such information is available.

  19. A physical multifield model predicts the development of volume and structure in the human brain

    Science.gov (United States)

    Rooij, Rijk de; Kuhl, Ellen

    2018-03-01

    The prenatal development of the human brain is characterized by a rapid increase in brain volume and a development of a highly folded cortex. At the cellular level, these events are enabled by symmetric and asymmetric cell division in the ventricular regions of the brain followed by an outwards cell migration towards the peripheral regions. The role of mechanics during brain development has been suggested and acknowledged in past decades, but remains insufficiently understood. Here we propose a mechanistic model that couples cell division, cell migration, and brain volume growth to accurately model the developing brain between weeks 10 and 29 of gestation. Our model accurately predicts a 160-fold volume increase from 1.5 cm3 at week 10 to 235 cm3 at week 29 of gestation. In agreement with human brain development, the cortex begins to form around week 22 and accounts for about 30% of the total brain volume at week 29. Our results show that cell division and coupling between cell density and volume growth are essential to accurately model brain volume development, whereas cell migration and diffusion contribute mainly to the development of the cortex. We demonstrate that complex folding patterns, including sinusoidal folds and creases, emerge naturally as the cortex develops, even for low stiffness contrasts between the cortex and subcortex.

  20. Adolescent Idiopathic Scoliosis Thoracic Volume Modeling: The Effect of Surgical Correction.

    Science.gov (United States)

    Wozniczka, Jennifer K; Ledonio, Charles G T; Polly, David W; Rosenstein, Benjamin E; Nuckley, David J

    2017-12-01

    Scoliosis has been shown to have detrimental effects on pulmonary function, traditionally measured by pulmonary function tests, which is theorized to be correlated to the distortion of the spine and thorax. The changes in thoracic volume with surgical correction have not been well quantified. This study seeks to define the effect of surgical correction on thoracic volume in patients with adolescent idiopathic scoliosis. Images were obtained from adolescents with idiopathic scoliosis enrolled in a multicenter database (Prospective Pediatric Scoliosis Study). A convenience sample of patients with Lenke type 1 curves with a complete data set meeting specific parameters was used. Blender v2.63a software was used to construct a 3-dimensional (3D) computational model of the spine from 2-dimensional calibrated radiographs. To accomplish this, the 3D thorax model was deformed to match the calibrated radiographs. The thorax volume was then calculated in cubic centimeters using Mimics v15 software. The results using this computational modeling technique demonstrated that surgical correction resulted in decreased curve measurement as determined by Cobb method, and increased postoperative thoracic volume as expected. Thoracic volume significantly increased by a mean of 567 mm (P3D changes in thoracic volumes using 2-dimensional imaging. This is an assessment of the novel modeling technique, to be used in larger future studies to assess clinical significance. Level 3-retrospective comparison of prospectively collected data.

  1. Developing a stochastic traffic volume prediction model for public-private partnership projects

    Science.gov (United States)

    Phong, Nguyen Thanh; Likhitruangsilp, Veerasak; Onishi, Masamitsu

    2017-11-01

    Transportation projects require an enormous amount of capital investment resulting from their tremendous size, complexity, and risk. Due to the limitation of public finances, the private sector is invited to participate in transportation project development. The private sector can entirely or partially invest in transportation projects in the form of Public-Private Partnership (PPP) scheme, which has been an attractive option for several developing countries, including Vietnam. There are many factors affecting the success of PPP projects. The accurate prediction of traffic volume is considered one of the key success factors of PPP transportation projects. However, only few research works investigated how to predict traffic volume over a long period of time. Moreover, conventional traffic volume forecasting methods are usually based on deterministic models which predict a single value of traffic volume but do not consider risk and uncertainty. This knowledge gap makes it difficult for concessionaires to estimate PPP transportation project revenues accurately. The objective of this paper is to develop a probabilistic traffic volume prediction model. First, traffic volumes were estimated following the Geometric Brownian Motion (GBM) process. Monte Carlo technique is then applied to simulate different scenarios. The results show that this stochastic approach can systematically analyze variations in the traffic volume and yield more reliable estimates for PPP projects.

  2. Finite-volume model for chemical vapor infiltration incorporating radiant heat transfer. Interim report

    Energy Technology Data Exchange (ETDEWEB)

    Smith, A.W.; Starr, T.L. [Georgia Institute of Technology, Atlanta, GA (United States). School of Materials Science and Engineering

    1995-05-01

    Most finite-volume thermal models account for the diffusion and convection of heat and may include volume heating. However, for certain simulation geometries, a large percentage of heat flux is due to thermal radiation. In this paper a finite-volume computational procedure for the simulation of heat transfer by conduction, convection and radiation in three dimensional complex enclosures is developed. The radiant heat transfer is included as a source term in each volume element which is derived by Monte Carlo ray tracing from all possible radiating and absorbing faces. The importance of radiative heat transfer is illustrated in the modeling of chemical vapor infiltration (CVI) of tubes. The temperature profile through the tube preform matches experimental measurements only when radiation is included. An alternative, empirical approach using an {open_quotes}effective{close_quotes} thermal conductivity for the gas space can match the initial temperature profile but does not match temperature changes that occur during preform densification.

  3. Probabilistic Modeling of Aircraft Trajectories for Dynamic Separation Volumes

    Science.gov (United States)

    Lewis, Timothy A.

    2016-01-01

    With a proliferation of new and unconventional vehicles and operations expected in the future, the ab initio airspace design will require new approaches to trajectory prediction for separation assurance and other air traffic management functions. This paper presents an approach to probabilistic modeling of the trajectory of an aircraft when its intent is unknown. The approach uses a set of feature functions to constrain a maximum entropy probability distribution based on a set of observed aircraft trajectories. This model can be used to sample new aircraft trajectories to form an ensemble reflecting the variability in an aircraft's intent. The model learning process ensures that the variability in this ensemble reflects the behavior observed in the original data set. Computational examples are presented.

  4. Recreation of architectural structures using procedural modeling based on volumes

    Directory of Open Access Journals (Sweden)

    Santiago Barroso Juan

    2013-11-01

    Full Text Available While the procedural modeling of buildings and other architectural structures has evolved very significantly in recent years, there is noticeable absence of high-level tools that allow a designer, an artist or an historian, creating important buildings or architectonic structures in a particular city. In this paper we present a tool for creating buildings in a simple and clear, following rules that use the language and methodology of creating their own buildings, and hiding the user the algorithmic details of the creation of the model.

  5. Pharmacodynamic modeling of propofol-induced tidal volume depression in children.

    Science.gov (United States)

    Hahn, Jin-Oh; Khosravi, Sara; Dosani, Maryam; Dumont, Guy A; Mark Ansermino, J

    2011-08-01

    This investigation aimed to develop a pediatric pharmacodynamic model of propofol-induced tidal volume depression towards an ultimate goal of developing a dosing schedule that would preserve spontaneous breathing following a loading dose of propofol. Fifty two ASA 1 and 2 children aged 6-15 year presenting for gastrointestinal endoscopy were enrolled. Subjects were administered a loading dose of 4 mg/kg of propofol intravenously at a constant infusion rate determined by a randomization schedule. Respiratory parameters including tidal volume, respiratory rate, minute volume, and end-tidal CO(2) were recorded at 5 s intervals. Using the predicted plasma concentration, based on the Paedfusor pharmacokinetic model, propofol-induced tidal volume depression was modeled by 3 different approaches (2-stage, pooled, and mixed effects) and results were compared using prediction residual, median percentage errors, median absolute percentage errors, and root-mean-squared normalized errors. The effects of age and body weight as covariates were examined. Respiratory rate and end-tidal CO(2) did not show clear dependence on the predicted plasma concentration. The pharmacodynamic models for tidal volume derived from different modeling approaches were highly consistent. The 2-stage, pooled, and mixed effects approaches yielded k(e0) of 1.06, 1.24, and 0.72 min(-1); γ of 1.10, 0.83, and 0.93; EC50 of 3.18, 3.44, and 3.00 mcg/ml. Including age and body weight as covariates did not significantly improve the predictive performance of the models. A pediatric pharmacodynamic model of propofol-induced tidal volume depression was developed. Models derived from 3 different approaches were shown to be consistent with each other; however, the individual pharmacodynamic parameters exhibited significant inter-individual variability without strong dependence on age and body weight. This would suggest the desirability of adapting the pharmacodynamic model to each subject in real time.

  6. Applying control volume finite element for modelling direct injection boom spraying flow

    OpenAIRE

    El Aissaoui, Abdellah; Lebeau, Frédéric; Destain, Marie-France; Houmy, Karim

    2009-01-01

    Assessment of injection lag transport and uniformity of direct injection boom sprayer is an important issue for successful variable rate spraying technology. To estimate the boom lag transport and pressure loss, a numerical model is formulated on the basis of fluid hydrodynamic conservation equations. The software is implemented in visual basic. To solve the pressure – velocities equations, control volume finite element method (CV) is used to delimit elementary volumes of the boom. Linearizat...

  7. Faster Deterministic Volume Estimation in the Oracle Model via Thin Lattice Coverings

    NARCIS (Netherlands)

    D.N. Dadush (Daniel)

    2015-01-01

    htmlabstractWe give a 2O(n)(1+1/")n time and poly(n)-space deterministic algorithm for computing a (1+")n approximation to the volume of a general convex body K, which comes close to matching the (1+c/")n/2 lower bound for volume estimation in the oracle model by Bárány and Füredi (STOC 1986,

  8. Volume Sculpting: Intuitive, Interactive 3D Shape Modelling

    DEFF Research Database (Denmark)

    Bærentzen, Jakob Andreas

    A system for interactive modelling of 3D shapes on a computer is presented. The system is intuitive and has a flat learning curve. It is especially well suited to the creation of organic shapes and shapes of complex topology. The interaction is simple; the user can either add new shape features...

  9. Modeling Degradation in Solid Oxide Electrolysis Cells - Volume II

    Energy Technology Data Exchange (ETDEWEB)

    Manohar Motwani

    2011-09-01

    Idaho National Laboratory has an ongoing project to generate hydrogen from steam using solid oxide electrolysis cells (SOECs). To accomplish this, technical and degradation issues associated with the SOECs will need to be addressed. This report covers various approaches being pursued to model degradation issues in SOECs. An electrochemical model for degradation of SOECs is presented. The model is based on concepts in local thermodynamic equilibrium in systems otherwise in global thermodynamic non-equilibrium. It is shown that electronic conduction through the electrolyte, however small, must be taken into account for determining local oxygen chemical potential,, within the electrolyte. The within the electrolyte may lie out of bounds in relation to values at the electrodes in the electrolyzer mode. Under certain conditions, high pressures can develop in the electrolyte just near the oxygen electrode/electrolyte interface, leading to oxygen electrode delamination. These predictions are in accordance with the reported literature on the subject. Development of high pressures may be avoided by introducing some electronic conduction in the electrolyte. By combining equilibrium thermodynamics, non-equilibrium (diffusion) modeling, and first-principles, atomic scale calculations were performed to understand the degradation mechanisms and provide practical recommendations on how to inhibit and/or completely mitigate them.

  10. Abelian Sandpile Model (ASM) and Infinite Volume Limit

    Indian Academy of Sciences (India)

    Self Organised Criticality (SOC). SOC- dynamics drive a system towards stationary state characterized by power law correlations in space and time. SOC- was proposed by [BTW 87,88] as a mechanism which could explain occurrence of fractal structures in diverse natural phenomena. ASM is a simple model where SOC ...

  11. 3D Modeling and Visualization of Geology Volume based on Geophysical Field Data

    Directory of Open Access Journals (Sweden)

    Min Qi

    2007-10-01

    Full Text Available 3D modeling and visualization of geology volume is very important to interpret accurately and locate subsurface geology volume for mining exploration and deep prospecting. However, it faces a lack of information because the target area is usually unexplored and lacks geological data. This paper presents our experience in applying a 3D model of geology volume based on geophysics. This work has researched and developed a 3D visualization system. It is based on an OO (orientated object approach and modular programming, uses the C++ language and Microsoft .NET platform. This system has built first a high resistivity method and MT database. The system uses irregular tetrahedrons to construct its model and then finally has built the 3D geological model itself.

  12. Modelling and Bayesian adaptive prediction of individual patients’ tumour volume change during radiotherapy

    International Nuclear Information System (INIS)

    Tariq, Imran; Chen, Tao; Kirkby, Norman F; Jena, Rajesh

    2016-01-01

    The aim of this study is to develop a mathematical modelling method that can predict individual patients’ response to radiotherapy, in terms of tumour volume change during the treatment. The main concept is to start from a population-average model, which is subsequently updated from an individual’s tumour volume measurement. The model becomes increasingly personalised and so too does the prediction it produces. This idea of adaptive prediction was realised by using a Bayesian approach for updating the model parameters. The feasibility of the developed method was demonstrated on the data from 25 non-small cell lung cancer patients treated with helical tomotherapy, during which tumour volume was measured from daily imaging as part of the image-guided radiotherapy. The method could provide useful information for adaptive treatment planning and dose scheduling based on the patient’s personalised response. (paper)

  13. Tree Root System Characterization and Volume Estimation by Terrestrial Laser Scanning and Quantitative Structure Modeling

    Directory of Open Access Journals (Sweden)

    Aaron Smith

    2014-12-01

    Full Text Available The accurate characterization of three-dimensional (3D root architecture, volume, and biomass is important for a wide variety of applications in forest ecology and to better understand tree and soil stability. Technological advancements have led to increasingly more digitized and automated procedures, which have been used to more accurately and quickly describe the 3D structure of root systems. Terrestrial laser scanners (TLS have successfully been used to describe aboveground structures of individual trees and stand structure, but have only recently been applied to the 3D characterization of whole root systems. In this study, 13 recently harvested Norway spruce root systems were mechanically pulled from the soil, cleaned, and their volumes were measured by displacement. The root systems were suspended, scanned with TLS from three different angles, and the root surfaces from the co-registered point clouds were modeled with the 3D Quantitative Structure Model to determine root architecture and volume. The modeling procedure facilitated the rapid derivation of root volume, diameters, break point diameters, linear root length, cumulative percentages, and root fraction counts. The modeled root systems underestimated root system volume by 4.4%. The modeling procedure is widely applicable and easily adapted to derive other important topological and volumetric root variables.

  14. ERDYM: Economic Recovery Dynamics Model. Volume 1. Modifications and Simulations.

    Science.gov (United States)

    1984-05-01

    factors of production and demands. The use of input-output structure can improve the realism of the analysis, thus it can aid the formation of policies...follow a neoclassical approach. The second maior *0.1 structural change to ERDYM is the addition of a monetary sector structured so that interest rates...changes, the investment sector 4 * still remains a neoclassical model of optimum capital accumulation rather than -01 the investment sector originally

  15. MARS CODE MANUAL VOLUME V: Models and Correlations

    International Nuclear Information System (INIS)

    Chung, Bub Dong; Bae, Sung Won; Lee, Seung Wook; Yoon, Churl; Hwang, Moon Kyu; Kim, Kyung Doo; Jeong, Jae Jun

    2010-02-01

    Korea Advanced Energy Research Institute (KAERI) conceived and started the development of MARS code with the main objective of producing a state-of-the-art realistic thermal hydraulic systems analysis code with multi-dimensional analysis capability. MARS achieves this objective by very tightly integrating the one dimensional RELAP5/MOD3 with the multi-dimensional COBRA-TF codes. The method of integration of the two codes is based on the dynamic link library techniques, and the system pressure equation matrices of both codes are implicitly integrated and solved simultaneously. In addition, the Equation-Of-State (EOS) for the light water was unified by replacing the EOS of COBRA-TF by that of the RELAP5. This models and correlations manual provides a complete list of detailed information of the thermal-hydraulic models used in MARS, so that this report would be very useful for the code users. The overall structure of the manual is modeled on the structure of the RELAP5 and as such the layout of the manual is very similar to that of the RELAP. This similitude to RELAP5 input is intentional as this input scheme will allow minimum modification between the inputs of RELAP5 and MARS3.1. MARS3.1 development team would like to express its appreciation to the RELAP5 Development Team and the USNRC for making this manual possible

  16. Modeling finite-volume effects and chiral symmetry breaking in two-flavor QCD thermodynamics

    Science.gov (United States)

    Klein, Bertram

    2017-11-01

    Finite-volume effects in Quantum Chromodynamics (QCD) have been a subject of much theoretical interest for more than two decades. They are in particular important for the analysis and interpretation of QCD simulations on a finite, discrete space-time lattice. Most of these effects are closely related to the phenomenon of spontaneous breaking of the chiral flavor symmetry and the emergence of pions as light Goldstone bosons. These long-range fluctuations are strongly affected by putting the system into a finite box, and an analysis with different methods can be organized according to the interplay between pion mass and box size. The finite volume also affects critical behavior at the chiral phase transition in QCD. In the present review, I will be mainly concerned with modeling such finite volume effects as they affect the thermodynamics of the chiral phase transition for two quark flavors. I review recent work on the analysis of finite-volume effects which makes use of the quark-meson model for dynamical chiral symmetry breaking. To account for the effects of critical long-range fluctuations close to the phase transition, most of the calculations have been performed using non-perturbative Renormalization Group (RG) methods. I give an overview over the application of these methods to a finite volume. The method, the model and the results are put into the context of related work in random matrix theory for very small volumes, chiral perturbation theory for larger volumes, and related methods and approaches. They are applied towards the analysis of finite-volume effects in lattice QCD simulations and their interpretation, mainly in the context of the chiral phase transition for two quark flavors.

  17. Tactical Target Acquisition Model (TATAC). Volume I. Analysts’ Manual,

    Science.gov (United States)

    1977-12-01

    Cockpit Obstructions C. THE SEARCH TERMo .... ... . . . ..... 0 1-8 D. DISCRIMINABILITY (P3 ) ".. ..-. ... I0-l X. DYNAMICS OF ACQUISITION...amplitude which will be designated the square wave flux response RSF(N(r ]** The mean value of g(x) is: 4S W [rK 1/2 N(r) R *[N(r) - 4"" .(r) K/ ( wr)osN...angles from 20* to 120* off the axis of the flight path using Cassegrain antenna designs . The MARSAM model was modified to account for this variable

  18. COMBINING 3D VOLUME AND MESH MODELS FOR REPRESENTING COMPLICATED HERITAGE BUILDINGS

    Directory of Open Access Journals (Sweden)

    F. Tsai

    2017-08-01

    Full Text Available This study developed a simple but effective strategy to combine 3D volume and mesh models for representing complicated heritage buildings and structures. The idea is to seamlessly integrate 3D parametric or polyhedral models and mesh-based digital surfaces to generate a hybrid 3D model that can take advantages of both modeling methods. The proposed hybrid model generation framework is separated into three phases. Firstly, after acquiring or generating 3D point clouds of the target, these 3D points are partitioned into different groups. Secondly, a parametric or polyhedral model of each group is generated based on plane and surface fitting algorithms to represent the basic structure of that region. A “bare-bones” model of the target can subsequently be constructed by connecting all 3D volume element models. In the third phase, the constructed bare-bones model is used as a mask to remove points enclosed by the bare-bones model from the original point clouds. The remaining points are then connected to form 3D surface mesh patches. The boundary points of each surface patch are identified and these boundary points are projected onto the surfaces of the bare-bones model. Finally, new meshes are created to connect the projected points and original mesh boundaries to integrate the mesh surfaces with the 3D volume model. The proposed method was applied to an open-source point cloud data set and point clouds of a local historical structure. Preliminary results indicated that the reconstructed hybrid models using the proposed method can retain both fundamental 3D volume characteristics and accurate geometric appearance with fine details. The reconstructed hybrid models can also be used to represent targets in different levels of detail according to user and system requirements in different applications.

  19. A simplified permeability model for coalbed methane reservoirs based on matchstick strain and constant volume theory

    Energy Technology Data Exchange (ETDEWEB)

    Ma, Qiang [China University of Mining and Technology, Beijing (China); Harpalani, Satya; Liu, Shimin [Southern Illinois University, Carbondale (United States)

    2011-01-01

    Significant changes occur in the absolute permeability of coalbed methane (CBM) reservoirs during primary depletion or enhanced recovery/CO{sub 2} sequestration operations. In order to project gas production, several analytical models have been developed to predict changes in coal permeability as a function of stress/porosity and sorption. Although these models are more transparent and less complicated than the coupled numerical models, there are differences between the various analytical models and there are several uncertainties. These are discussed briefly in this paper. A new model is then proposed, which is based on the volumetric balance between the bulk coal, and solid grains and pores, using the constant volume theory. It incorporates primarily the changes in grain and cleat volumes and is, therefore, different from the other models that lay heavy emphasis on the pore volume/cleat compressibility values. Finally, in order to demonstrate the simplicity of the proposed model, a history matching exercise is carried out using field data in order to compare the different models. The modeling results suggest that the agreement between the predicted permeability using the existing models and the one proposed here is very good. The merit of the proposed model is its simplicity, and the fact that all input parameters are easily measurable for any coal type with no uncertainties. (author)

  20. Model documentation: Natural gas transmission and distribution model of the National Energy Modeling System. Volume 1

    International Nuclear Information System (INIS)

    1995-01-01

    The Natural Gas Transmission and Distribution Model (NGTDM) is the component of the National Energy Modeling System (NEMS) that is used to represent the domestic natural gas transmission and distribution system. NEMS was developed in the Office of integrated Analysis and Forecasting of the Energy information Administration (EIA). NEMS is the third in a series of computer-based, midterm energy modeling systems used since 1974 by the EIA and its predecessor, the Federal Energy Administration, to analyze domestic energy-economy markets and develop projections. The NGTDM is the model within the NEMS that represents the transmission, distribution, and pricing of natural gas. The model also includes representations of the end-use demand for natural gas, the production of domestic natural gas, and the availability of natural gas traded on the international market based on information received from other NEMS models. The NGTDM determines the flow of natural gas in an aggregate, domestic pipeline network, connecting domestic and foreign supply regions with 12 demand regions. The methodology employed allows the analysis of impacts of regional capacity constraints in the interstate natural gas pipeline network and the identification of pipeline capacity expansion requirements. There is an explicit representation of core and noncore markets for natural gas transmission and distribution services, and the key components of pipeline tariffs are represented in a pricing algorithm. Natural gas pricing and flow patterns are derived by obtaining a market equilibrium across the three main elements of the natural gas market: the supply element, the demand element, and the transmission and distribution network that links them. The NGTDM consists of four modules: the Annual Flow Module, the Capacity F-expansion Module, the Pipeline Tariff Module, and the Distributor Tariff Module. A model abstract is provided in Appendix A

  1. Model documentation: Natural gas transmission and distribution model of the National Energy Modeling System. Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-02-17

    The Natural Gas Transmission and Distribution Model (NGTDM) is the component of the National Energy Modeling System (NEMS) that is used to represent the domestic natural gas transmission and distribution system. NEMS was developed in the Office of integrated Analysis and Forecasting of the Energy information Administration (EIA). NEMS is the third in a series of computer-based, midterm energy modeling systems used since 1974 by the EIA and its predecessor, the Federal Energy Administration, to analyze domestic energy-economy markets and develop projections. The NGTDM is the model within the NEMS that represents the transmission, distribution, and pricing of natural gas. The model also includes representations of the end-use demand for natural gas, the production of domestic natural gas, and the availability of natural gas traded on the international market based on information received from other NEMS models. The NGTDM determines the flow of natural gas in an aggregate, domestic pipeline network, connecting domestic and foreign supply regions with 12 demand regions. The methodology employed allows the analysis of impacts of regional capacity constraints in the interstate natural gas pipeline network and the identification of pipeline capacity expansion requirements. There is an explicit representation of core and noncore markets for natural gas transmission and distribution services, and the key components of pipeline tariffs are represented in a pricing algorithm. Natural gas pricing and flow patterns are derived by obtaining a market equilibrium across the three main elements of the natural gas market: the supply element, the demand element, and the transmission and distribution network that links them. The NGTDM consists of four modules: the Annual Flow Module, the Capacity F-expansion Module, the Pipeline Tariff Module, and the Distributor Tariff Module. A model abstract is provided in Appendix A.

  2. Volume-Targeted Ventilation in the Neonate: Benchmarking Ventilators on an Active Lung Model.

    Science.gov (United States)

    Krieger, Tobias J; Wald, Martin

    2017-03-01

    Mechanically ventilated neonates have been observed to receive substantially different ventilation after switching ventilator models, despite identical ventilator settings. This study aims at establishing the range of output variability among 10 neonatal ventilators under various breathing conditions. Relative benchmarking test of 10 neonatal ventilators on an active neonatal lung model. Neonatal ICU. Ten current neonatal ventilators. Ventilators were set identically to flow-triggered, synchronized, volume-targeted, pressure-controlled, continuous mandatory ventilation and connected to a neonatal lung model. The latter was configured to simulate three patients (500, 1,500, and 3,500 g) in three breathing modes each (passive breathing, constant active breathing, and variable active breathing). Averaged across all weight conditions, the included ventilators delivered between 86% and 110% of the target tidal volume in the passive mode, between 88% and 126% during constant active breathing, and between 86% and 120% under variable active breathing. The largest relative deviation occurred during the 500 g constant active condition, where the highest output machine produced 147% of the tidal volume of the lowest output machine. All machines deviate significantly in volume output and ventilation regulation. These differences depend on ventilation type, respiratory force, and patient behavior, preventing the creation of a simple conversion table between ventilator models. Universal neonatal tidal volume targets for mechanical ventilation cannot be transferred from one ventilator to another without considering necessary adjustments.

  3. An advective volume-balance model for flow in porous media

    Science.gov (United States)

    Malaga, Carlos; Mandujano, Francisco; Becerra, Julian

    2016-11-01

    Volume-balance models are used by petroleum engineers to simulate multiphase and multicomponent flow phenomena in porous media and the extraction process in oil reservoirs. In these models, mass conservation equations and Darcy's law are supplemented by a balance condition for the pore and fluid volumes. This provides a pressure equation suitable for simulating a compressible flow within a compressible solid matrix. Here we present an alternative interpretation of the volume-balance condition that includes the advective transport within a consolidated porous media. We obtain a modified equation for the time evolution of the pressure field. Preliminary numerical tests of phase separation due to gravity suggest the model reproduces qualitatively the physical phenomena. Fondo Sectorial CONACYT-SENER Grant Number 42536 (DGAJ-SPI-34-170412-217).

  4. Glass Transition Temperature of Saccharide Aqueous Solutions Estimated with the Free Volume/Percolation Model.

    Science.gov (United States)

    Constantin, Julian Gelman; Schneider, Matthias; Corti, Horacio R

    2016-06-09

    The glass transition temperature of trehalose, sucrose, glucose, and fructose aqueous solutions has been predicted as a function of the water content by using the free volume/percolation model (FVPM). This model only requires the molar volume of water in the liquid and supercooled regimes, the molar volumes of the hypothetical pure liquid sugars at temperatures below their pure glass transition temperatures, and the molar volumes of the mixtures at the glass transition temperature. The model is simplified by assuming that the excess thermal expansion coefficient is negligible for saccharide-water mixtures, and this ideal FVPM becomes identical to the Gordon-Taylor model. It was found that the behavior of the water molar volume in trehalose-water mixtures at low temperatures can be obtained by assuming that the FVPM holds for this mixture. The temperature dependence of the water molar volume in the supercooled region of interest seems to be compatible with the recent hypothesis on the existence of two structure of liquid water, being the high density liquid water the state of water in the sugar solutions. The idealized FVPM describes the measured glass transition temperature of sucrose, glucose, and fructose aqueous solutions, with much better accuracy than both the Gordon-Taylor model based on an empirical kGT constant dependent on the saccharide glass transition temperature and the Couchman-Karasz model using experimental heat capacity changes of the components at the glass transition temperature. Thus, FVPM seems to be an excellent tool to predict the glass transition temperature of other aqueous saccharides and polyols solutions by resorting to volumetric information easily available.

  5. Precise determination of universal finite volume observables in the Gross-Neveu model

    International Nuclear Information System (INIS)

    Korzec, T.

    2007-01-01

    The Gross-Neveu model is a quantum field theory in two space time dimensions that shares many features with quantum chromo dynamics. In this thesis the continuum model and its discretized versions are reviewed and a finite volume renormalization scheme is introduced and tested. Calculations in the limit of infinitely many fermion flavors as well as perturbative computations are carried out. In extensive Monte-Carlo simulations of the one flavor and the four flavor lattice models with Wilson fermions a set of universal finite volume observables is calculated to a high precision. In the one flavor model which is equivalent to the massless Thirring model the continuum extrapolated Monte-Carlo results are confronted with an exact solution of the model. (orig.)

  6. Integrating Model of the Project Independence Evaluation System. Volume III. User's Guide

    Energy Technology Data Exchange (ETDEWEB)

    Shaw, M.L.; Hutzler, M.J.

    1979-03-01

    Volume III of the six-volume series documenting the Integrating Model of PIES provides a potential PIES user with a description of how PIES operates with particular emphasis on the possible variations in assumptions and data that can be made in specifying alternative scenarios. PIES is described as it existed on January 1, 1978. The introductory chapter is followed by Section II, an overview of the structure and components of PIES. Section III discusses each of the PIES components in detail; describes the Demand Model; contains a description of the models, assumptions, and data which provide supply side inputs to the PIES Integrating Model; and concludes with a discussion of those aspects of PIES which extend the scope of the analysis beyond the national energy market. Section IV discusses two reports produced by the PIES Integrating Model: the PIES Integrating Model Report and the Coal Transportation Report. (MCW)

  7. Absorption and scattering coefficient dependence of laser-Doppler flowmetry models for large tissue volumes

    International Nuclear Information System (INIS)

    Binzoni, T; Leung, T S; Ruefenacht, D; Delpy, D T

    2006-01-01

    Based on quasi-elastic scattering theory (and random walk on a lattice approach), a model of laser-Doppler flowmetry (LDF) has been derived which can be applied to measurements in large tissue volumes (e.g. when the interoptode distance is >30 mm). The model holds for a semi-infinite medium and takes into account the transport-corrected scattering coefficient and the absorption coefficient of the tissue, and the scattering coefficient of the red blood cells. The model holds for anisotropic scattering and for multiple scattering of the photons by the moving scatterers of finite size. In particular, it has also been possible to take into account the simultaneous presence of both Brownian and pure translational movements. An analytical and simplified version of the model has also been derived and its validity investigated, for the case of measurements in human skeletal muscle tissue. It is shown that at large optode spacing it is possible to use the simplified model, taking into account only a 'mean' light pathlength, to predict the blood flow related parameters. It is also demonstrated that the 'classical' blood volume parameter, derived from LDF instruments, may not represent the actual blood volume variations when the investigated tissue volume is large. The simplified model does not need knowledge of the tissue optical parameters and thus should allow the development of very simple and cost-effective LDF hardware

  8. Automated modelling of spatially-distributed glacier ice thickness and volume

    Science.gov (United States)

    James, William H. M.; Carrivick, Jonathan L.

    2016-07-01

    Ice thickness distribution and volume are both key parameters for glaciological and hydrological applications. This study presents VOLTA (Volume and Topography Automation), which is a Python script tool for ArcGISTM that requires just a digital elevation model (DEM) and glacier outline(s) to model distributed ice thickness, volume and bed topography. Ice thickness is initially estimated at points along an automatically generated centreline network based on the perfect-plasticity rheology assumption, taking into account a valley side drag component of the force balance equation. Distributed ice thickness is subsequently interpolated using a glaciologically correct algorithm. For five glaciers with independent field-measured bed topography, VOLTA modelled volumes were between 26.5% (underestimate) and 16.6% (overestimate) of that derived from field observations. Greatest differences were where an asymmetric valley cross section shape was present or where significant valley infill had occurred. Compared with other methods of modelling ice thickness and volume, key advantages of VOLTA are: a fully automated approach and a user friendly graphical user interface (GUI), GIS consistent geometry, fully automated centreline generation, inclusion of a side drag component in the force balance equation, estimation of glacier basal shear stress for each individual glacier, fully distributed ice thickness output and the ability to process multiple glaciers rapidly. VOLTA is capable of regional scale ice volume assessment, which is a key parameter for exploring glacier response to climate change. VOLTA also permits subtraction of modelled ice thickness from the input surface elevation to produce an ice-free DEM, which is a key input for reconstruction of former glaciers. VOLTA could assist with prediction of future glacier geometry changes and hence in projection of future meltwater fluxes.

  9. Joint modelling of flood peaks and volumes: A copula application for the Danube River

    Directory of Open Access Journals (Sweden)

    Papaioannou George

    2016-12-01

    Full Text Available Flood frequency analysis is usually performed as a univariate analysis of flood peaks using a suitable theoretical probability distribution of the annual maximum flood peaks or peak over threshold values. However, other flood attributes, such as flood volume and duration, are necessary for the design of hydrotechnical projects, too. In this study, the suitability of various copula families for a bivariate analysis of peak discharges and flood volumes has been tested. Streamflow data from selected gauging stations along the whole Danube River have been used. Kendall’s rank correlation coefficient (tau quantifies the dependence between flood peak discharge and flood volume settings. The methodology is applied to two different data samples: 1 annual maximum flood (AMF peaks combined with annual maximum flow volumes of fixed durations at 5, 10, 15, 20, 25, 30 and 60 days, respectively (which can be regarded as a regime analysis of the dependence between the extremes of both variables in a given year, and 2 annual maximum flood (AMF peaks with corresponding flood volumes (which is a typical choice for engineering studies. The bivariate modelling of the extracted peak discharge - flood volume couples is achieved with the use of the Ali-Mikhail-Haq (AMH, Clayton, Frank, Joe, Gumbel, Hüsler-Reiss, Galambos, Tawn, Normal, Plackett and FGM copula families. Scatterplots of the observed and simulated peak discharge - flood volume pairs and goodness-of-fit tests have been used to assess the overall applicability of the copulas as well as observing any changes in suitable models along the Danube River. The results indicate that for the second data sampling method, almost all of the considered Archimedean class copula families perform better than the other copula families selected for this study, and that for the first method, only the upper-tail-flat copulas excel (except for the AMH copula due to its inability to model stronger relationships.

  10. Performance Prediction Modelling for Flexible Pavement on Low Volume Roads Using Multiple Linear Regression Analysis

    Directory of Open Access Journals (Sweden)

    C. Makendran

    2015-01-01

    Full Text Available Prediction models for low volume village roads in India are developed to evaluate the progression of different types of distress such as roughness, cracking, and potholes. Even though the Government of India is investing huge quantum of money on road construction every year, poor control over the quality of road construction and its subsequent maintenance is leading to the faster road deterioration. In this regard, it is essential that scientific maintenance procedures are to be evolved on the basis of performance of low volume flexible pavements. Considering the above, an attempt has been made in this research endeavor to develop prediction models to understand the progression of roughness, cracking, and potholes in flexible pavements exposed to least or nil routine maintenance. Distress data were collected from the low volume rural roads covering about 173 stretches spread across Tamil Nadu state in India. Based on the above collected data, distress prediction models have been developed using multiple linear regression analysis. Further, the models have been validated using independent field data. It can be concluded that the models developed in this study can serve as useful tools for the practicing engineers maintaining flexible pavements on low volume roads.

  11. ATHENA code manual. Volume 1. Code structure, system models, and solution methods

    International Nuclear Information System (INIS)

    Carlson, K.E.; Roth, P.A.; Ransom, V.H.

    1986-09-01

    The ATHENA (Advanced Thermal Hydraulic Energy Network Analyzer) code has been developed to perform transient simulation of the thermal hydraulic systems which may be found in fusion reactors, space reactors, and other advanced systems. A generic modeling approach is utilized which permits as much of a particular system to be modeled as necessary. Control system and secondary system components are included to permit modeling of a complete facility. Several working fluids are available to be used in one or more interacting loops. Different loops may have different fluids with thermal connections between loops. The modeling theory and associated numerical schemes are documented in Volume I in order to acquaint the user with the modeling base and thus aid effective use of the code. The second volume contains detailed instructions for input data preparation

  12. Glass Property Data and Models for Estimating High-Level Waste Glass Volume

    International Nuclear Information System (INIS)

    Vienna, John D.; Fluegel, Alexander; Kim, Dong-Sang; Hrma, Pavel R.

    2009-01-01

    This report describes recent efforts to develop glass property models that can be used to help estimate the volume of high-level waste (HLW) glass that will result from vitrification of Hanford tank waste. The compositions of acceptable and processable HLW glasses need to be optimized to minimize the waste-form volume and, hence, to save cost. A database of properties and associated compositions for simulated waste glasses was collected for developing property-composition models. This database, although not comprehensive, represents a large fraction of data on waste-glass compositions and properties that were available at the time of this report. Glass property-composition models were fit to subsets of the database for several key glass properties. These models apply to a significantly broader composition space than those previously publised. These models should be considered for interim use in calculating properties of Hanford waste glasses.

  13. Models for high cell density bioreactors must consider biomass volume fraction: Cell recycle example.

    Science.gov (United States)

    Monbouquette, H G

    1987-06-01

    Intrinsic models, which take into account biomass volume fraction, must be formulated for adequate simulation of high-biomass-density fermentations with cell recycle. Through comparison of corresponding intrinsic and non-intrinsic models in dimensionless form, constraints for non-intrinsic model usage in terms of biokinetic and fermenter operating parameters can be identified a priori. Analysis of a simple product-inhibition model indicates that the non-intrinsic approach is suitable only when the attainable biomass volume fraction in the fermentation broth is less than about 0.10. Inappropriate application of a non-intrinsic model can lead to gross errors in calculated substrate and product concentrations, substrate conversion, and volumetric productivity.

  14. Models for high cell density bioreactors must consider biomass volume fraction: cell recycle example

    Energy Technology Data Exchange (ETDEWEB)

    Monbouquette, H.G.

    1987-06-01

    Intrinsic models, which take into account biomass volume fraction, must be formulated for adequate simulation of high-biomass-density fermentations with cell recycle. Through comparison of corresponding intrinsic and non-intrinsic models in dimensionless form, constraints for non-intrinsic model usage in terms of biokinetic and fermenter operating parameters can be identified a priori. Analysis of a simple product-inhibition model indicates that the non-intrinsic approach is suitable only when the attainable biomass volume fraction in the fermentation broth is less than about 0.10. Inappropriate application of a non-intrinsic model can lead to gross errors in calculated substrate and product concentrations, substrate conversion, and volumetric productivity. (Refs. 14).

  15. Glass Property Data and Models for Estimating High-Level Waste Glass Volume

    Energy Technology Data Exchange (ETDEWEB)

    Vienna, John D.; Fluegel, Alexander; Kim, Dong-Sang; Hrma, Pavel R.

    2009-10-05

    This report describes recent efforts to develop glass property models that can be used to help estimate the volume of high-level waste (HLW) glass that will result from vitrification of Hanford tank waste. The compositions of acceptable and processable HLW glasses need to be optimized to minimize the waste-form volume and, hence, to save cost. A database of properties and associated compositions for simulated waste glasses was collected for developing property-composition models. This database, although not comprehensive, represents a large fraction of data on waste-glass compositions and properties that were available at the time of this report. Glass property-composition models were fit to subsets of the database for several key glass properties. These models apply to a significantly broader composition space than those previously publised. These models should be considered for interim use in calculating properties of Hanford waste glasses.

  16. Continuous modelling study of numerical volumes - Applications to the visualization of anatomical structures

    International Nuclear Information System (INIS)

    Goret, C.

    1990-12-01

    Several technics of imaging (IRM, image scanners, tomoscintigraphy, echography) give numerical informations presented by means of a stack of parallel cross-sectional images. Since many years, 3-D mathematical tools have been developed and allow the 3 D images synthesis of surfaces. In first part, we give the technics of numerical volume exploitation and their medical applications to diagnosis and therapy. The second part is about a continuous modelling of the volume with a tensor product of cubic splines. We study the characteristics of this representation and its clinical validation. Finally, we treat of the problem of surface visualization of objects contained in the volume. The results show the interest of this model and allow to propose specifications for 3-D workstation realization [fr

  17. MELSAR: a mesoscale air quality model for complex terrain. Volume 2. Appendices

    Energy Technology Data Exchange (ETDEWEB)

    Allwine, K.J.; Whiteman, C.D.

    1985-04-01

    This final report is submitted as part of the Green River Ambient Model Assessment (GRAMA) project conducted at the US Department of Energy's Pacific Northwest Laboratory for the US Environmental Protection Agency. The GRAMA Program has, as its ultimate goal, the development of validated air quality models that can be applied to the complex terrain of the Green River Formation of western Colorado, eastern Utah and southern Wyoming. The Green River Formation is a geologic formation containing large reserves of oil shale, coal, and other natural resources. Development of these resources may lead to a degradation of the air quality of the region. Air quality models are needed immediately for planning and regulatory purposes to assess the magnitude of these regional impacts. This report documents one of the models being developed for this purpose within GRAMA - specifically a model to predict short averaging time (less than or equal to 24 h) pollutant concentrations resulting from the mesoscale transport of pollutant releases from multiple sources. MELSAR has not undergone any rigorous operational testing, sensitivity analyses, or validation studies. Testing and evaluation of the model are needed to gain a measure of confidence in the model's performance. This report consists of two volumes. This volume contains the Appendices, which include listings of the FORTRAN code and Volume 1 contains the model overview, technical description, and user's guide. 13 figs., 10 tabs.

  18. A model to incorporate organ deformation in the evaluation of dose/volume relationship

    International Nuclear Information System (INIS)

    Yan, D.; Jaffray, D.; Wong, J.; Brabbins, D.; Martinez, A. A.

    1997-01-01

    Purpose: Measurements of internal organ motion have demonstrated that daily organ deformation exists during the course of radiation treatment. However, a model to evaluate the resultant dose delivered to a daily deformed organ remains a difficult challenge. Current methods which model such organ deformation as rigid body motion in the dose calculation for treatment planning evaluation are incorrect and misleading. In this study, a new model for treatment planning evaluation is introduced which incorporates patient specific information of daily organ deformation and setup variation. The model was also used to retrospectively analyze the actual treatment data measured using daily CT scans for 5 patients with prostate treatment. Methods and Materials: The model assumes that for each patient, the organ of interest can be measured during the first few treatment days. First, the volume of each organ is delineated from each of the daily measurements and cumulated in a 3D bit-map. A tissue occupancy distribution is then constructed with the 50% isodensity representing the mean, or effective, organ volume. During the course of treatment, each voxel in the effective organ volume is assumed to move inside a local 3D neighborhood with a specific distribution function. The neighborhood and the distribution function are deduced from the positions and shapes of the organ in the first few measurements using the biomechanics model of viscoelastic body. For each voxel, the local distribution function is then convolved with the spatial dose distribution. The latter includes also the variation in dose due to daily setup error. As a result, the cumulative dose to the voxel incorporates the effects of daily setup variation and organ deformation. A ''variation adjusted'' dose volume histogram, aDVH, for the effective organ volume can then be constructed for the purpose of treatment evaluation and optimization. Up to 20 daily CT scans and daily portal images for 5 patients with prostate

  19. On the Use of Generalized Volume Scattering Models for the Improvement of General Polarimetric Model-Based Decomposition

    Directory of Open Access Journals (Sweden)

    Qinghua Xie

    2017-01-01

    Full Text Available Recently, a general polarimetric model-based decomposition framework was proposed by Chen et al., which addresses several well-known limitations in previous decomposition methods and implements a simultaneous full-parameter inversion by using complete polarimetric information. However, it only employs four typical models to characterize the volume scattering component, which limits the parameter inversion performance. To overcome this issue, this paper presents two general polarimetric model-based decomposition methods by incorporating the generalized volume scattering model (GVSM or simplified adaptive volume scattering model, (SAVSM proposed by Antropov et al. and Huang et al., respectively, into the general decomposition framework proposed by Chen et al. By doing so, the final volume coherency matrix structure is selected from a wide range of volume scattering models within a continuous interval according to the data itself without adding unknowns. Moreover, the new approaches rely on one nonlinear optimization stage instead of four as in the previous method proposed by Chen et al. In addition, the parameter inversion procedure adopts the modified algorithm proposed by Xie et al. which leads to higher accuracy and more physically reliable output parameters. A number of Monte Carlo simulations of polarimetric synthetic aperture radar (PolSAR data are carried out and show that the proposed method with GVSM yields an overall improvement in the final accuracy of estimated parameters and outperforms both the version using SAVSM and the original approach. In addition, C-band Radarsat-2 and L-band AIRSAR fully polarimetric images over the San Francisco region are also used for testing purposes. A detailed comparison and analysis of decomposition results over different land-cover types are conducted. According to this study, the use of general decomposition models leads to a more accurate quantitative retrieval of target parameters. However, there

  20. Real-time bladder volume monitoring by the application of a new implantable bladder volume sensor for a small animal model

    Directory of Open Access Journals (Sweden)

    Dong Sup Lee

    2011-04-01

    Full Text Available Although real-time monitoring of bladder volume together with intravesical pressure can provide more information for understanding the functional changes of the urinary bladder, it still entails difficulties in the accurate prediction of real-time bladder volume in urodynamic studies with small animal models. We studied a new implantable bladder volume monitoring device with eight rats. During cystometry, microelectrodes prepared by the microelectromechanical systems process were placed symmetrically on both lateral walls of the bladder, and the expanded bladder volume was calculated. Immunohistological study was done after 1 week and after 4 weeks to evaluate the biocompatibility of the microelectrode. From the point that infused saline volume into the bladder was higher than 0.6 mL, estimated bladder volume was statistically correlated with the volume of saline injected (p<0.01. Additionally, the microelectromechanical system microelectrodes used in this study showed reliable biocompatibility. Therefore, the device can be used to evaluate changes in bladder volume in studies with small animals, and it may help to provide more information about functional changes in the bladder in laboratory studies. Furthermore, owing to its biocompatibility, the device could be chronically implanted in conscious ambulating animals, thus allowing a novel longitudinal study to be performed for a specific purpose.

  1. Sensitivity Analysis of Wavelet Neural Network Model for Short-Term Traffic Volume Prediction

    Directory of Open Access Journals (Sweden)

    Jinxing Shen

    2013-01-01

    Full Text Available In order to achieve a more accurate and robust traffic volume prediction model, the sensitivity of wavelet neural network model (WNNM is analyzed in this study. Based on real loop detector data which is provided by traffic police detachment of Maanshan, WNNM is discussed with different numbers of input neurons, different number of hidden neurons, and traffic volume for different time intervals. The test results show that the performance of WNNM depends heavily on network parameters and time interval of traffic volume. In addition, the WNNM with 4 input neurons and 6 hidden neurons is the optimal predictor with more accuracy, stability, and adaptability. At the same time, a much better prediction record will be achieved with the time interval of traffic volume are 15 minutes. In addition, the optimized WNNM is compared with the widely used back-propagation neural network (BPNN. The comparison results indicated that WNNM produce much lower values of MAE, MAPE, and VAPE than BPNN, which proves that WNNM performs better on short-term traffic volume prediction.

  2. Comparison of Moving Boundary and Finite-Volume Heat Exchanger Models in the Modelica Language

    Directory of Open Access Journals (Sweden)

    Adriano Desideri

    2016-05-01

    Full Text Available When modeling low capacity energy systems, such as a small size (5–150 kWel organic Rankine cycle unit, the governing dynamics are mainly concentrated in the heat exchangers. As a consequence, the accuracy and simulation speed of the higher level system model mainly depend on the heat exchanger model formulation. In particular, the modeling of thermo-flow systems characterized by evaporation or condensation requires heat exchanger models capable of handling phase transitions. To this aim, the finite volume (FV and the moving boundary (MB approaches are the most widely used. The two models are developed and included in the open-source ThermoCycle Modelica library. In this contribution, a comparison between the two approaches is presented. An integrity and accuracy test is designed to evaluate the performance of the FV and MB models during transient conditions. In order to analyze how the two modeling approaches perform when integrated at a system level, two organic Rankine cycle (ORC system models are built using the FV and the MB evaporator model, and their responses are compared against experimental data collected on an 11 kWel ORC power unit. Additionally, the effect of the void fraction value in the MB evaporator model and of the number of control volumes (CVs in the FV one is investigated. The results allow drawing general guidelines for the development of heat exchanger dynamic models involving two-phase flows.

  3. Volume and Aboveground Biomass Models for Dry Miombo Woodland in Tanzania

    Directory of Open Access Journals (Sweden)

    Ezekiel Edward Mwakalukwa

    2014-01-01

    Full Text Available Tools to accurately estimate tree volume and biomass are scarce for most forest types in East Africa, including Tanzania. Based on a sample of 142 trees and 57 shrubs from a 6,065 ha area of dry miombo woodland in Iringa rural district in Tanzania, regression models were developed for volume and biomass of three important species, Brachystegia spiciformis Benth. (n = 40, Combretum molle G. Don (n = 41, and Dalbergia arbutifolia Baker (n = 37 separately, and for broader samples of trees (28 species, n = 72, shrubs (16 species, n = 32, and trees and shrubs combined (44 species, n = 104. Applied independent variables were log-transformed diameter, height, and wood basic density, and in each case a range of different models were tested. The general tendency among the final models is that the fit improved when height and wood basic density were included. Also the precision and accuracy of the predictions tended to increase from general to species-specific models. Except for a few volume and biomass models developed for shrubs, all models had R2 values of 96–99%. Thus, the models appear robust and should be applicable to forests with similar site conditions, species, and diameter ranges.

  4. RELAP5/MOD3 code manual: Code structure, system models, and solution methods. Volume 1

    International Nuclear Information System (INIS)

    1995-08-01

    The RELAP5 code has been developed for best estimate transient simulation of light water reactor coolant systems during postulated accidents. The code models the coupled behavior of the reactor coolant system and the core for loss-of-coolant accidents, and operational transients, such as anticipated transient without scram, loss of offsite power, loss of feedwater, and loss of flow. A generic modeling, approach is used that permits simulating a variety of thermal hydraulic systems. Control system and secondary system components are included to permit modeling of plant controls, turbines, condensers, and secondary feedwater systems. RELAP5/MOD3 code documentation is divided into seven volumes: Volume I provides modeling theory and associated numerical schemes

  5. Volume Averaging Theory (VAT) based modeling and closure evaluation for fin-and-tube heat exchangers

    Science.gov (United States)

    Zhou, Feng; Catton, Ivan

    2012-10-01

    A fin-and-tube heat exchanger was modeled based on Volume Averaging Theory (VAT) in such a way that the details of the original structure was replaced by their averaged counterparts, so that the VAT based governing equations can be efficiently solved for a wide range of parameters. To complete the VAT based model, proper closure is needed, which is related to a local friction factor and a heat transfer coefficient of a Representative Elementary Volume (REV). The terms in the closure expressions are complex and sometimes relating experimental data to the closure terms is difficult. In this work we use CFD to evaluate the rigorously derived closure terms over one of the selected REVs. The objective is to show how heat exchangers can be modeled as a porous media and how CFD can be used in place of a detailed, often formidable, experimental effort to obtain closure for the model.

  6. Computational Methods for Protein Structure Prediction and Modeling Volume 1: Basic Characterization

    CERN Document Server

    Xu, Ying; Liang, Jie

    2007-01-01

    Volume one of this two volume sequence focuses on the basic characterization of known protein structures as well as structure prediction from protein sequence information. The 11 chapters provide an overview of the field, covering key topics in modeling, force fields, classification, computational methods, and struture prediction. Each chapter is a self contained review designed to cover (1) definition of the problem and an historical perspective, (2) mathematical or computational formulation of the problem, (3) computational methods and algorithms, (4) performance results, (5) existing software packages, and (6) strengths, pitfalls, challenges, and future research directions.

  7. The Development of a Finite Volume Method for Modeling Sound in Coastal Ocean Environment

    Energy Technology Data Exchange (ETDEWEB)

    Long, Wen; Yang, Zhaoqing; Copping, Andrea E.; Jung, Ki Won; Deng, Zhiqun

    2015-10-28

    : As the rapid growth of marine renewable energy and off-shore wind energy, there have been concerns that the noises generated from construction and operation of the devices may interfere marine animals’ communication. In this research, a underwater sound model is developed to simulate sound prorogation generated by marine-hydrokinetic energy (MHK) devices or offshore wind (OSW) energy platforms. Finite volume and finite difference methods are developed to solve the 3D Helmholtz equation of sound propagation in the coastal environment. For finite volume method, the grid system consists of triangular grids in horizontal plane and sigma-layers in vertical dimension. A 3D sparse matrix solver with complex coefficients is formed for solving the resulting acoustic pressure field. The Complex Shifted Laplacian Preconditioner (CSLP) method is applied to efficiently solve the matrix system iteratively with MPI parallelization using a high performance cluster. The sound model is then coupled with the Finite Volume Community Ocean Model (FVCOM) for simulating sound propagation generated by human activities in a range-dependent setting, such as offshore wind energy platform constructions and tidal stream turbines. As a proof of concept, initial validation of the finite difference solver is presented for two coastal wedge problems. Validation of finite volume method will be reported separately.

  8. Electric field distribution in a finite-volume head model of deep brain stimulation.

    Science.gov (United States)

    Grant, Peadar F; Lowery, Madeleine M

    2009-11-01

    This study presents a whole-head finite element model of deep brain stimulation to examine the effect of electrical grounding, the finite conducting volume of the head, and scalp, skull and cerebrospinal fluid layers. The impedance between the stimulating and reference electrodes in the whole-head model was found to lie within clinically reported values when the reference electrode was incorporated on a localized surface in the model. Incorporation of the finite volume of the head and inclusion of surrounding outer tissue layers reduced the magnitude of the electric field and activating function by approximately 20% in the region surrounding the electrode. Localized distortions of the electric field were also observed when the electrode was placed close to the skull. Under bipolar conditions the effect of the finite conducting volume was shown to be negligible. The results indicate that, for monopolar stimulation, incorporation of the finite volume and outer tissue layers can alter the magnitude of the electric field and activating function when the electrode is deep within the brain, and may further affect the shape if the electrode is close to the skull.

  9. A structural model of age, grey matter volumes, education, and personality traits.

    Science.gov (United States)

    Kitamura, Soichiro; Yasuno, Fumihiko; Yamamoto, Akihide; Kazui, Hiroaki; Kudo, Takashi; Matsuoka, Kiwamu; Kiuchi, Kuniaki; Kosaka, Jun; Nagatsuka, Kazuyuki; Iida, Hidehiro; Kishimoto, Toshifumi

    2016-01-01

    When the relationship between ageing and changes in personality traits is considered, it is important to know how they are influenced by biological and environmental factors. The present study examined the relationships between various factors associated with the effect of ageing on personality traits, including structural changes of the brain and environmental factors such as education. We recruited 41 healthy subjects. We administered the NEO Five-Factor Inventory to assess personality factors. Magnetic resonance imaging was performed, and regional grey matter (GM) volumes were obtained. We identified associations in the correlation analysis of age, cerebral GM volume, years of education, and the personality trait of openness. Path analysis was used to estimate the relationships among these factors. The path analysis model of age, GM volume, years of education, and the personality trait of openness revealed that age has an indirect negative association with openness through GM volume and years of education. Ageing was related to a decrease in GM volume, which was in turn related to a decrease in the openness score. Older subjects generally had fewer years of education, which was related to a lower openness score. Maintaining openness against the effects of ageing is desirable, and our results imply that interventions against age-related cerebral atrophy and the promotion of opportunities for higher education may contribute to the development and stability of a healthy personality during the adult life course. © 2015 The Authors. Psychogeriatrics © 2015 Japanese Psychogeriatric Society.

  10. A Control Volume Model of Solute Transport in a Single Fracture

    Science.gov (United States)

    Kennedy, Christopher A.; Lennox, William C.

    1995-02-01

    A control volume model of solute transport through a single fracture in a porous matrix is developed. Application to problems of contaminant transport through fractured clay demonstrates several strong features of the method. The control volume approach inherently conserves mass and treats dispersivity at interfaces in a physically correct manner. By employing an upstream weighting scheme, based on the exact solution to the one-dimensional steady state advection-dispersion equation, the model proves to be more efficient than previous single-fracture models. The significance of matrix diffusion in the direction parallel to the fracture axis is investigated. For the transport of a nonreactive tracer through a 20-micrometer-wide fracture in clay material, analytical solutions based on one-dimensional matrix diffusion are erroneous for flow velocities of less than 1 m/day. The influence of boundary conditions on two-dimensional matrix diffusion is considered, and the clean-up of a contaminated fracture is simulated.

  11. Simulation model for wind energy storage systems. Volume III. Program descriptions. [SIMWEST CODE

    Energy Technology Data Exchange (ETDEWEB)

    Warren, A.W.; Edsinger, R.W.; Burroughs, J.D.

    1977-08-01

    The effort developed a comprehensive computer program for the modeling of wind energy/storage systems utilizing any combination of five types of storage (pumped hydro, battery, thermal, flywheel and pneumatic). An acronym for the program is SIMWEST (Simulation Model for Wind Energy Storage). The level of detail of SIMWEST is consistent with a role of evaluating the economic feasibility as well as the general performance of wind energy systems. The software package consists of two basic programs and a library of system, environmental, and load components. Volume III, the SIMWEST program description contains program descriptions, flow charts and program listings for the SIMWEST Model Generation Program, the Simulation program, the File Maintenance program and the Printer Plotter program. Volume III generally would not be required by SIMWEST user.

  12. Modeling Accumulated Volume of Landslides Using Remote Sensing and DTM Data

    Directory of Open Access Journals (Sweden)

    Zhengchao Chen

    2014-02-01

    Full Text Available Landslides, like other natural hazards, such as avalanches, floods, and debris flows, may result in a lot of property damage and human casualties. The volume of landslide deposits is a key parameter for landslide studies and disaster relief. Using remote sensing and digital terrain model (DTM data, this paper analyzes errors that can occur in calculating landslide volumes using conventional models. To improve existing models, the mechanisms and laws governing the material deposited by landslides are studied and then the mass balance principle and mass balance line are defined. Based on these ideas, a novel and improved model (Mass Balance Model, MBM is proposed. By using a parameter called the “height adaptor”, MBM translates the volume calculation into an automatic search for the mass balance line within the scope of the landslide. Due to the use of mass balance constraints and the height adaptor, MBM is much more effective and reliable. A test of MBM was carried out for the case of a typical landslide, triggered by the Wenchuan Earthquake of 12 May 2008.

  13. Measurement and modeling of advanced coal conversion processes, Volume I, Part 2. Final report, September 1986--September 1993

    Energy Technology Data Exchange (ETDEWEB)

    Solomon, P.R.; Serio, M.A.; Hamblen, D.G. [and others

    1995-09-01

    This report describes work pertaining to the development of models for coal gasification and combustion processes. This volume, volume 1, part 2, contains research progress in the areas of large particle oxidation at high temperatures, large particle, thick-bed submodels, sulfur oxide/nitrogen oxides submodels, and comprehensive model development and evaluation.

  14. Models of cognitive behavior in nuclear power plant personnel. A feasibility study: main report. Volume 2

    International Nuclear Information System (INIS)

    Woods, D.D.; Roth, E.M.; Hanes, L.F.

    1986-07-01

    This report contains the results of a feasibility study to determine if the current state of models human cognitive activities can serve as the basis for improved techniques for predicting human error in nuclear power plants emergency operations. Based on the answer to this questions, two subsequent phases of research are planned. Phase II is to develop a model of cognitive activities, and Phase III is to test the model. The feasibility study included an analysis of the cognitive activities that occur in emergency operations and an assessment of the modeling concepts/tools available to capture these cognitive activities. The results indicated that a symbolic processing (or artificial intelligence) model of cognitive activities in nuclear power plants is both desirable and feasible. This cognitive model can be built upon the computational framework provided by an existing artificial intelligence system for medical problem solving called Caduceus. The resulting cognitive model will increase the capability to capture the human contribution to risk in probabilistic risk assessments studies. Volume I summarizes the major findings and conclusions of the study. Volume II provides a complete description of the methods and results, including a synthesis of the cognitive activities that occur during emergency operations, and a literature review on cognitive modeling relevant to nuclear power plants. 112 refs., 10 figs

  15. Verification of Conjugate Heat Transfer Models in a Closed Volume with Radiative Heat Source

    Directory of Open Access Journals (Sweden)

    Maksimov Vyacheslav I.

    2016-01-01

    Full Text Available The results of verification of mathematical model of convective-conductive heat transfer in a closed volume with a thermally conductive enclosing structures are presented. Experiments were carried out to determine the temperature of floor premises in the working conditions of radiant heating systems. Comparison of mathematical modelling of temperature fields and experiments showed their good agreement. It is concluded that the mathematical model of conjugate heat transfers in the air cavity with a heat-conducting and heat-retaining walls correspond to the real process of formation of temperature fields in premises with gas infrared heaters system.

  16. Understanding the growth mechanism of carbon nanotubes via the ``cluster volume to surface area" model

    Science.gov (United States)

    Mandati, Sreekanth; Kunstmann, Jens; Boerrnert, Felix; Schoenfelder, Ronny; Ruemmeli, Mark; Kar, Kamal K.; Cuniberti, Gianaurelio

    2010-03-01

    The influence of mixed catalysts for the high yield production of carbon nanotubes (CNTs) has been studied systematically. Based on extensive experimental data a ``Catalyst Volume to Surface Area'' (CVSA) model was developed to understand the influence of the process parameters on the yield and CNT diameter distribution [1]. In our study, we present a refined version of the CVSA model developed by combining experiments and simulations. We discuss our current understanding of the growth mechanism and how the model might be used to increase CNT yields by using mixed catalysts.[4pt] [1] S. Tetali et al., ACS Nano (2009), DOI: 10.1021/nn9012548.

  17. Statistical modeling of volume of alcohol exposure for epidemiological studies of population health: the US example

    Directory of Open Access Journals (Sweden)

    Gmel Gerrit

    2010-03-01

    Full Text Available Abstract Background Alcohol consumption is a major risk factor in the global burden of disease, with overall volume of exposure as the principal underlying dimension. Two main sources of data on volume of alcohol exposure are available: surveys and per capita consumption derived from routine statistics such as taxation. As both sources have significant problems, this paper presents an approach that triangulates information from both sources into disaggregated estimates in line with the overall level of per capita consumption. Methods A modeling approach was applied to the US using data from a large and representative survey, the National Epidemiologic Survey on Alcohol and Related Conditions. Different distributions (log-normal, gamma, Weibull were used to model consumption among drinkers in subgroups defined by sex, age, and ethnicity. The gamma distribution was used to shift the fitted distributions in line with the overall volume as derived from per capita estimates. Implications for alcohol-attributable fractions were presented, using liver cirrhosis as an example. Results The triangulation of survey data with aggregated per capita consumption data proved feasible and allowed for modeling of alcohol exposure disaggregated by sex, age, and ethnicity. These models can be used in combination with risk relations for burden of disease calculations. Sensitivity analyses showed that the gamma distribution chosen yielded very similar results in terms of fit and alcohol-attributable mortality as the other tested distributions. Conclusions Modeling alcohol consumption via the gamma distribution was feasible. To further refine this approach, research should focus on the main assumptions underlying the approach to explore differences between volume estimates derived from surveys and per capita consumption figures.

  18. Conversion of a Surface Model of a Structure of Interest into a Volume Model for Medical Image Retrieval

    Directory of Open Access Journals (Sweden)

    Sarmad ISTEPHAN

    2015-06-01

    Full Text Available Volumetric medical image datasets contain vital information for noninvasive diagnosis, treatment planning and prognosis. However, direct and unlimited query of such datasets is hindered due to the unstructured nature of the imaging data. This study is a step towards the unlimited query of medical image datasets by focusing on specific Structures of Interest (SOI. A requirement in achieving this objective is having both the surface and volume models of the SOI. However, typically, only the surface model is available. Therefore, this study focuses on creating a fast method to convert a surface model to a volume model. Three methods (1D, 2D and 3D are proposed and evaluated using simulated and real data of Deep Perisylvian Area (DPSA within the human brain. The 1D method takes 80 msec for DPSA model; about 4 times faster than 2D method and 7.4 fold faster than 3D method, with over 97% accuracy. The proposed 1D method is feasible for surface to volume conversion in computer aided diagnosis, treatment planning and prognosis systems containing large amounts of unstructured medical images.

  19. Iterative model reconstruction reduces calcified plaque volume in coronary CT angiography

    Energy Technology Data Exchange (ETDEWEB)

    Károlyi, Mihály, E-mail: mihaly.karolyi@cirg.hu [MTA-SE Cardiovascular Imaging Research Group, Heart and Vascular Center, Semmelweis University, 68. Varosmajor st, 1122, Budapest (Hungary); Szilveszter, Bálint, E-mail: szilveszter.balint@gmail.com [MTA-SE Cardiovascular Imaging Research Group, Heart and Vascular Center, Semmelweis University, 68. Varosmajor st, 1122, Budapest (Hungary); Kolossváry, Márton, E-mail: martonandko@gmail.com [MTA-SE Cardiovascular Imaging Research Group, Heart and Vascular Center, Semmelweis University, 68. Varosmajor st, 1122, Budapest (Hungary); Takx, Richard A.P, E-mail: richard.takx@gmail.com [Department of Radiology, University Medical Center Utrecht, 100 Heidelberglaan, 3584, CX Utrecht (Netherlands); Celeng, Csilla, E-mail: celengcsilla@gmail.com [MTA-SE Cardiovascular Imaging Research Group, Heart and Vascular Center, Semmelweis University, 68. Varosmajor st, 1122, Budapest (Hungary); Bartykowszki, Andrea, E-mail: bartyandi@gmail.com [MTA-SE Cardiovascular Imaging Research Group, Heart and Vascular Center, Semmelweis University, 68. Varosmajor st, 1122, Budapest (Hungary); Jermendy, Ádám L., E-mail: adam.jermendy@gmail.com [MTA-SE Cardiovascular Imaging Research Group, Heart and Vascular Center, Semmelweis University, 68. Varosmajor st, 1122, Budapest (Hungary); Panajotu, Alexisz, E-mail: panajotualexisz@gmail.com [MTA-SE Cardiovascular Imaging Research Group, Heart and Vascular Center, Semmelweis University, 68. Varosmajor st, 1122, Budapest (Hungary); Karády, Júlia, E-mail: karadyjulia@gmail.com [MTA-SE Cardiovascular Imaging Research Group, Heart and Vascular Center, Semmelweis University, 68. Varosmajor st, 1122, Budapest (Hungary); and others

    2017-02-15

    Objective: To assess the impact of iterative model reconstruction (IMR) on calcified plaque quantification as compared to filtered back projection reconstruction (FBP) and hybrid iterative reconstruction (HIR) in coronary computed tomography angiography (CTA). Methods: Raw image data of 52 patients who underwent 256-slice CTA were reconstructed with IMR, HIR and FBP. We evaluated qualitative, quantitative image quality parameters and quantified calcified and partially calcified plaque volumes using automated software. Results: Overall qualitative image quality significantly improved with HIR as compared to FBP, and further improved with IMR (p < 0.01 all). Contrast-to-noise ratios were improved with IMR, compared to HIR and FBP (51.0 [43.5–59.9], 20.3 [16.2–25.9] and 14.0 [11.2–17.7], respectively, all p < 0.01) Overall plaque volumes were lowest with IMR and highest with FBP (121.7 [79.3–168.4], 138.7 [90.6–191.7], 147.0 [100.7–183.6]). Similarly, calcified volumes (>130 HU) were decreased with IMR as compared to HIR and FBP (105.9 [62.1–144.6], 110.2 [63.8–166.6], 115.9 [81.7–164.2], respectively, p < 0.05 all). High-attenuation non-calcified volumes (90–129 HU) yielded similar values with FBP and HIR (p = 0.81), however it was lower with IMR (p < 0.05 both). Intermediate- (30–89 HU) and low-attenuation (<30 HU) non-calcified volumes showed no significant difference (p = 0.22 and p = 0.67, respectively). Conclusions: IMR improves image quality of coronary CTA and decreases calcified plaque volumes.

  20. Integrating model of the Project Independence Evaluation System. Volume VI. Data documentation. Part II

    Energy Technology Data Exchange (ETDEWEB)

    Allen, B J

    1979-02-01

    This documentation describes the PIES Integrating Model as it existed on January 1, 1978. This Volume VI of six volumes is data documentation, containing the standard table data used for the Administrator's Report at the beginning of 1978, along with the primary data sources and the office responsible. It also contains a copy of a PIES Integrating Model Report with a description of its content. Following an overview chapter, Chapter II, Supply and Demand Data Tables and Sources for the Mid-range Scenario for Target Years 1985 and 1990, data on demand, price, and elasticity; coal; imports; oil and gas; refineries; synthetics, shale, and solar/geothermal; transportation; and utilities are presented. The following data on alternate scenarios are discussed: low and high demand; low and high oil and gas supply; refinery and oil and gas data assuming a 5% annual increase in real world oil prices. Chapter IV describes the solution output obtained from an execution of PIES.

  1. 3-D reconstruction and volume modelling of the grain fabric of geological materials

    Science.gov (United States)

    Marschallinger, R.

    This paper describes three-dimensional reconstruction and volume modelling of geological materials at the macroscopic and the microscopic scale. By means of a precision lapping device, samples are eroded in plan-parallel steps, erosion intervals being adapted to the size of minerals and fabric features of interest. For reconstruction of macroscopic features, each newly eroded sample surface is recorded by a high-resolution color flatbed scanner. Supervised image classification applied to the derived images yields color based mineral recognition. At the microscopic scale, scanning is done with a microanalyzer to portray mineral phases and microchemical variation. Minerals and fabric features are three dimensionally reconstructed by stacking and interpolating the acquired raster images of successive erosion levels in a voxel array. The voxel data structure features analyical flexibility, integration of both discrete and continuous spatial variation and versatile 3-D volume model visualization.

  2. Monte Carlo method for critical systems in infinite volume: The planar Ising model.

    Science.gov (United States)

    Herdeiro, Victor; Doyon, Benjamin

    2016-10-01

    In this paper we propose a Monte Carlo method for generating finite-domain marginals of critical distributions of statistical models in infinite volume. The algorithm corrects the problem of the long-range effects of boundaries associated to generating critical distributions on finite lattices. It uses the advantage of scale invariance combined with ideas of the renormalization group in order to construct a type of "holographic" boundary condition that encodes the presence of an infinite volume beyond it. We check the quality of the distribution obtained in the case of the planar Ising model by comparing various observables with their infinite-plane prediction. We accurately reproduce planar two-, three-, and four-point of spin and energy operators. We also define a lattice stress-energy tensor, and numerically obtain the associated conformal Ward identities and the Ising central charge.

  3. Simulation model for wind energy storage systems. Volume II. Operation manual. [SIMWEST code

    Energy Technology Data Exchange (ETDEWEB)

    Warren, A.W.; Edsinger, R.W.; Burroughs, J.D.

    1977-08-01

    The effort developed a comprehensive computer program for the modeling of wind energy/storage systems utilizing any combination of five types of storage (pumped hydro, battery, thermal, flywheel and pneumatic). An acronym for the program is SIMWEST (Simulation Model for Wind Energy Storage). The level of detail of SIMWEST is consistent with a role of evaluating the economic feasibility as well as the general performance of wind energy systems. The software package consists of two basic programs and a library of system, environmental, and load components. Volume II, the SIMWEST operation manual, describes the usage of the SIMWEST program, the design of the library components, and a number of simple example simulations intended to familiarize the user with the program's operation. Volume II also contains a listing of each SIMWEST library subroutine.

  4. Modelling the Hydraulic Behaviour of Growing Media with the Explicit Finite Volume Solution

    Directory of Open Access Journals (Sweden)

    Marco Carbone

    2015-02-01

    Full Text Available The increasing imperviousness of urban areas reduces the infiltration and evapotranspiration capacity of urban catchments and results in increased runoff. In the last few decades, several solutions and techniques have been proposed to prevent such impacts by restoring the hydrological cycle. A limiting factor in spreading the use of such systems is the lack of proper modelling tools for design, especially for the infiltration processes in a growing medium. In this research, a physically-based model, employing the explicit Finite Volume Method (FVM, is proposed for modelling infiltration into growing media. The model solves a modified version of the Richards equation using a formulation which takes into account the main characteristics of green infrastructure substrates. The proposed model was verified against the HYDRUS-1D software and the comparison of results confirmed the suitability of the proposed model for correctly describing the hydraulic behaviour of soil substrates.

  5. Verification and transfer of thermal pollution model. Volume 3: Verification of 3-dimensional rigid-lid model

    Science.gov (United States)

    Lee, S. S.; Sengupta, S.; Nwadike, E. V.; Sinha, S. K.

    1982-01-01

    The six-volume report: describes the theory of a three dimensional (3-D) mathematical thermal discharge model and a related one dimensional (1-D) model, includes model verification at two sites, and provides a separate user's manual for each model. The 3-D model has two forms: free surface and rigid lid. The former, verified at Anclote Anchorage (FL), allows a free air/water interface and is suited for significant surface wave heights compared to mean water depth; e.g., estuaries and coastal regions. The latter, verified at Lake Keowee (SC), is suited for small surface wave heights compared to depth (e.g., natural or man-made inland lakes) because surface elevation has been removed as a parameter. These models allow computation of time-dependent velocity and temperature fields for given initial conditions and time-varying boundary conditions. The free-surface model also provides surface height variations with time.

  6. AN AUTOMATIC FEATURE BASED MODEL FOR CELL SEGMENTATION FROM CONFOCAL MICROSCOPY VOLUMES

    OpenAIRE

    Delibaltov, Diana; Ghosh, Pratim; Veeman, Michael; Smith, William; Manjunath, B.S.

    2011-01-01

    We present a model for the automated segmentation of cells from confocal microscopy volumes of biological samples. The segmentation task for these images is exceptionally challenging due to weak boundaries and varying intensity during the imaging process. To tackle this, a two step pruning process based on the Fast Marching Method is first applied to obtain an over-segmented image. This is followed by a merging step based on an effective feature representation. The algorithm is applied on two...

  7. Applying Training System Estimation Models to Army Training. Volume 2. An Annotated Bibliography 1970-1990

    Science.gov (United States)

    1994-05-01

    associated with the Educational Technology Assessment Model ( ETAM ). It contains relevant background information and results of prior studies leading to...the finalized ETAM procedures and computerized routines. A comparison of the manual and automated approach is included, and data base structures and... ETAM program flow are described. The second volume (see PA, Vol 59:11358) contains the 344-page appendix. 039Duffy, L.R., Miller, R.B., & Staley, J.D

  8. Control volume based modelling in one space dimension of oscillating, compressible flow in reciprocating machines

    DEFF Research Database (Denmark)

    Andersen, Stig Kildegård; Carlsen, Henrik; Thomsen, Per Grove

    2006-01-01

    We present an approach for modelling unsteady, primarily one-dimensional, compressible flow. The conservation laws for mass, energy, and momentum are applied to a staggered mesh of control volumes and loss mechanisms are included directly as extra terms. Heat transfer, flow friction......, and multidimensional effects are calculated using empirical correlations. Transformations of the conservation equations into new variables, artificial dissipation for dissipating acoustic phenomena, and an asymmetric interpolation method for minimising numerical diffusion and non physical temperature oscillations...

  9. Model-based segmentation in orbital volume measurement with cone beam computed tomography and evaluation against current concepts.

    Science.gov (United States)

    Wagner, Maximilian E H; Gellrich, Nils-Claudius; Friese, Karl-Ingo; Becker, Matthias; Wolter, Franz-Erich; Lichtenstein, Juergen T; Stoetzer, Marcus; Rana, Majeed; Essig, Harald

    2016-01-01

    Objective determination of the orbital volume is important in the diagnostic process and in evaluating the efficacy of medical and/or surgical treatment of orbital diseases. Tools designed to measure orbital volume with computed tomography (CT) often cannot be used with cone beam CT (CBCT) because of inferior tissue representation, although CBCT has the benefit of greater availability and lower patient radiation exposure. Therefore, a model-based segmentation technique is presented as a new method for measuring orbital volume and compared to alternative techniques. Both eyes from thirty subjects with no known orbital pathology who had undergone CBCT as a part of routine care were evaluated (n = 60 eyes). Orbital volume was measured with manual, atlas-based, and model-based segmentation methods. Volume measurements, volume determination time, and usability were compared between the three methods. Differences in means were tested for statistical significance using two-tailed Student's t tests. Neither atlas-based (26.63 ± 3.15 mm(3)) nor model-based (26.87 ± 2.99 mm(3)) measurements were significantly different from manual volume measurements (26.65 ± 4.0 mm(3)). However, the time required to determine orbital volume was significantly longer for manual measurements (10.24 ± 1.21 min) than for atlas-based (6.96 ± 2.62 min, p model-based (5.73 ± 1.12 min, p measurements. All three orbital volume measurement methods examined can accurately measure orbital volume, although atlas-based and model-based methods seem to be more user-friendly and less time-consuming. The new model-based technique achieves fully automated segmentation results, whereas all atlas-based segmentations at least required manipulations to the anterior closing. Additionally, model-based segmentation can provide reliable orbital volume measurements when CT image quality is poor.

  10. Engineered materials characterization report for the Yucca Mountain Site Characterization Project. Volume 3: Corrosion and data modeling

    International Nuclear Information System (INIS)

    Van Konynenburg, R.A.; McCright, R.D.; Roy, A.K.; Jones, D.A.

    1995-08-01

    This three-volume report serves several purposes. The first volume provides an introduction to the engineered materials effort for the Yucca Mountain Site Characterization Project. It defines terms and outlines the history of selection and characterization of these materials. A summary of the recent engineered barrier materials characterization workshop is presented, and the current candidate materials are listed. The second volume tabulates design data for engineered materials, and the third volume is devoted to corrosion data, radiation effects on corrosion, and corrosion modeling. The second and third volumes are intended to be evolving documents, to which new data will be added as they become available from additional studies. The initial version of Volume 3 is devoted to information currently available for environments most similar to those expected in the potential Yucca Mountain repository. This is volume three

  11. Productivity Analysis of Volume Fractured Vertical Well Model in Tight Oil Reservoirs

    Directory of Open Access Journals (Sweden)

    Jiahang Wang

    2017-01-01

    Full Text Available This paper presents a semianalytical model to simulate the productivity of a volume fractured vertical well in tight oil reservoirs. In the proposed model, the reservoir is a composite system which contains two regions. The inner region is described as formation with finite conductivity hydraulic fracture network and the flow in fracture is assumed to be linear, while the outer region is simulated by the classical Warren-Root model where radial flow is applied. The transient rate is calculated, and flow patterns and characteristic flowing periods caused by volume fractured vertical well are analyzed. Combining the calculated results with actual production data at the decline stage shows a good fitting performance. Finally, the effects of some sensitive parameters on the type curves are also analyzed extensively. The results demonstrate that the effect of fracture length is more obvious than that of fracture conductivity on improving production in tight oil reservoirs. When the length and conductivity of main fracture are constant, the contribution of stimulated reservoir volume (SRV to the cumulative oil production is not obvious. When the SRV is constant, the length of fracture should also be increased so as to improve the fracture penetration and well production.

  12. Methods to Increase the Robustness of Finite-Volume Flow Models in Thermodynamic Systems

    Directory of Open Access Journals (Sweden)

    Sylvain Quoilin

    2014-03-01

    Full Text Available This paper addresses the issues linked to simulation failures during integration in finite-volume flow models, especially those involving a two-phase state. This kind of model is particularly useful when modeling 1D heat exchangers or piping, e.g., in thermodynamic cycles involving a phase change. Issues, such as chattering or stiff systems, can lead to low simulation speed, instabilities and simulation failures. In the particular case of two-phase flow models, they are usually linked to a discontinuity in the density derivative between the liquid and two-phase zones. In this work, several methods to tackle numerical problems are developed, described, implemented and compared. In addition, methods available in the literature are also implemented and compared to the proposed approaches. Results suggest that the robustness of the models can be significantly increased with these different methods, at the price of a small increase of the error in the mass and energy balances.

  13. Classical and recent free-volume models for polymer solutions: A comparative evaluation

    DEFF Research Database (Denmark)

    Radfarnia, H.R.; Kontogeorgis, Georgios; Ghotbi, C.

    2007-01-01

    In this work, two "classical" (UNIFAC-FV, Entropic-FV) and two "recent" free-volume (FV) models (Kannan-FV, Freed-FV) are comparatively evaluated for polymer-solvent vapor-liquid equilibria including both aqueous and non-aqueous solutions. Moreover, some further developments are presented here...... by the modified Freed-FV model for athermal and non-athermal polymer systems are compared to other "recent" and "classical" FV models, indicating an improvement for the modified Freed-FV model for aqueous polymer solutions. Second, for the original Freed-FV model, new UNIFAC group energy parameters are regressed...... to using the classical UNIFAC parameters, for VLE of aqueous and alcohol polymer systems....

  14. Verification and transfer of thermal pollution model. Volume 2: User's manual for 3-dimensional free-surface model

    Science.gov (United States)

    Lee, S. S.; Sengupta, S.; Tuann, S. Y.; Lee, C. R.

    1982-01-01

    The six-volume report: describes the theory of a three-dimensional (3-D) mathematical thermal discharge model and a related one-dimensional (1-D) model, includes model verification at two sites, and provides a separate user's manual for each model. The 3-D model has two forms: free surface and rigid lid. The former, verified at Anclote Anchorage (FL), allows a free air/water interface and is suited for significant surface wave heights compared to mean water depth; e.g., estuaries and coastal regions. The latter, verified at Lake Keowee (SC), is suited for small surface wave heights compared to depth. These models allow computation of time-dependent velocity and temperature fields for given initial conditions and time-varying boundary conditions.

  15. Effect of stand structure on models for volume and aboveground biomass assessment (Castelfusano pinewood, Roma

    Directory of Open Access Journals (Sweden)

    2009-03-01

    Full Text Available The main purpose of this research was to analyse the effects of stand structure on biomass allocation and on the accurancy of estimation models for volume and aboveground biomass of Italian stone pine (Pinus pinea L.. Although the species is widely distributed on Mediterranean coasts, few studies on forest biomass estimation have focused on pinewoods. The research was carried out in the Castelfusano’s pinewood (Rome and concerned the two most common structural types: (a 50 years-old pinewood originated by broadcast seeding; and (b 62 years-old pinewood originated by partial seeding alternating worked strips to firm strips. Some 83 sample trees were selected for stem volume estimation and a subset of 32 trees used to quantify the total epigeous biomass, the wooden biomass compartment, including stem and big branches (diameter > 3 cm and the photosynthetic biomass, including thin branches (diameter < 3 cm and needles. Collected data were used to elaborate allometric relations for stem volume, total biomass and specific relations for both compartments, based on one (d2 or two (d2h indipendent variables, for both structural types. Furthermore, pinewood specific biomass expansion factors (BEF - indexes used to estimate carbon stocks starting from stem biomass data - were obtained. The achieved estimation models were subjected to both parallelism and coincidence tests, showing significant effects of stand structure on the accurancy of the allometric relations. The effects of stand structure and reliability of tree height curves on the accurancy of estimation models for volume and aboveground biomass and on biomass allocation in different compartments are analysed and discussed.

  16. Integrating model of the Project Independence Evaluation System. Volume VI. Data documentation. Part I

    Energy Technology Data Exchange (ETDEWEB)

    Allen, B J

    1979-02-01

    This documentation describes the PIES Integrating Model as it existed on January 1, 1978. This volume contains two chapters. In Chapter I, Overview, the following subjects are briefly described: supply data, EIA projection series and scenarios, demand data and assumptions, and supply assumptions - oil and gas availabilities. Chapter II contains supply and demand data tables and sources used by the PIES Integrating Model for the mid-range scenario target years 1985 and 1990. Tabulated information is presented for demand, price, and elasticity data; coal data; imports data; oil and gas data; refineries data; synthetics, shale, and solar/geothermal data; transportation data; and utilities data.

  17. Measurements and Modeling of Soot Formation and Radiation in Microgravity Jet Diffusion Flames. Volume 4

    Science.gov (United States)

    Ku, Jerry C.; Tong, Li; Greenberg, Paul S.

    1996-01-01

    This is a computational and experimental study for soot formation and radiative heat transfer in jet diffusion flames under normal gravity (1-g) and microgravity (0-g) conditions. Instantaneous soot volume fraction maps are measured using a full-field imaging absorption technique developed by the authors. A compact, self-contained drop rig is used for microgravity experiments in the 2.2-second drop tower facility at NASA Lewis Research Center. On modeling, we have coupled flame structure and soot formation models with detailed radiation transfer calculations. Favre-averaged boundary layer equations with a k-e-g turbulence model are used to predict the flow field, and a conserved scalar approach with an assumed Beta-pdf are used to predict gaseous species mole fraction. Scalar transport equations are used to describe soot volume fraction and number density distributions, with formation and oxidation terms modeled by one-step rate equations and thermophoretic effects included. An energy equation is included to couple flame structure and radiation analyses through iterations, neglecting turbulence-radiation interactions. The YIX solution for a finite cylindrical enclosure is used for radiative heat transfer calculations. The spectral absorption coefficient for soot aggregates is calculated from the Rayleigh solution using complex refractive index data from a Drude- Lorentz model. The exponential-wide-band model is used to calculate the spectral absorption coefficient for H20 and C02. It is shown that when compared to results from true spectral integration, the Rosseland mean absorption coefficient can provide reasonably accurate predictions for the type of flames studied. The soot formation model proposed by Moss, Syed, and Stewart seems to produce better fits to experimental data and more physically sound than the simpler model by Khan et al. Predicted soot volume fraction and temperature results agree well with published data for a normal gravity co-flow laminar

  18. Long-Term Prediction of Emergency Department Revenue and Visitor Volume Using Autoregressive Integrated Moving Average Model

    Directory of Open Access Journals (Sweden)

    Chieh-Fan Chen

    2011-01-01

    Full Text Available This study analyzed meteorological, clinical and economic factors in terms of their effects on monthly ED revenue and visitor volume. Monthly data from January 1, 2005 to September 30, 2009 were analyzed. Spearman correlation and cross-correlation analyses were performed to identify the correlation between each independent variable, ED revenue, and visitor volume. Autoregressive integrated moving average (ARIMA model was used to quantify the relationship between each independent variable, ED revenue, and visitor volume. The accuracies were evaluated by comparing model forecasts to actual values with mean absolute percentage of error. Sensitivity of prediction errors to model training time was also evaluated. The ARIMA models indicated that mean maximum temperature, relative humidity, rainfall, non-trauma, and trauma visits may correlate positively with ED revenue, but mean minimum temperature may correlate negatively with ED revenue. Moreover, mean minimum temperature and stock market index fluctuation may correlate positively with trauma visitor volume. Mean maximum temperature, relative humidity and stock market index fluctuation may correlate positively with non-trauma visitor volume. Mean maximum temperature and relative humidity may correlate positively with pediatric visitor volume, but mean minimum temperature may correlate negatively with pediatric visitor volume. The model also performed well in forecasting revenue and visitor volume.

  19. Coupling model of aerobic waste degradation considering temperature, initial moisture content and air injection volume.

    Science.gov (United States)

    Ma, Jun; Liu, Lei; Ge, Sai; Xue, Qiang; Li, Jiangshan; Wan, Yong; Hui, Xinminnan

    2018-03-01

    A quantitative description of aerobic waste degradation is important in evaluating landfill waste stability and economic management. This research aimed to develop a coupling model to predict the degree of aerobic waste degradation. On the basis of the first-order kinetic equation and the law of conservation of mass, we first developed the coupling model of aerobic waste degradation that considered temperature, initial moisture content and air injection volume to simulate and predict the chemical oxygen demand in the leachate. Three different laboratory experiments on aerobic waste degradation were simulated to test the model applicability. Parameter sensitivity analyses were conducted to evaluate the reliability of parameters. The coupling model can simulate aerobic waste degradation, and the obtained simulation agreed with the corresponding results of the experiment. Comparison of the experiment and simulation demonstrated that the coupling model is a new approach to predict aerobic waste degradation and can be considered as the basis for selecting the economic air injection volume and appropriate management in the future.

  20. A mathematical model relating cortical oxygenated and deoxygenated hemoglobin flows and volumes to neural activity

    Science.gov (United States)

    Cornelius, Nathan R.; Nishimura, Nozomi; Suh, Minah; Schwartz, Theodore H.; Doerschuk, Peter C.

    2015-08-01

    Objective. To describe a toolkit of components for mathematical models of the relationship between cortical neural activity and space-resolved and time-resolved flows and volumes of oxygenated and deoxygenated hemoglobin motivated by optical intrinsic signal imaging (OISI). Approach. Both blood flow and blood volume and both oxygenated and deoxygenated hemoglobin and their interconversion are accounted for. Flow and volume are described by including analogies to both resistive and capacitive electrical circuit elements. Oxygenated and deoxygenated hemoglobin and their interconversion are described by generalization of Kirchhoff's laws based on well-mixed compartments. Main results. Mathematical models built from this toolkit are able to reproduce experimental single-stimulus OISI results that are described in papers from other research groups and are able to describe the response to multiple-stimuli experiments as a sublinear superposition of responses to the individual stimuli. Significance. The same assembly of tools from the toolkit but with different parameter values is able to describe effects that are considered distinctive, such as the presence or absence of an initial decrease in oxygenated hemoglobin concentration, indicating that the differences might be due to unique parameter values in a subject rather than different fundamental mechanisms.

  1. Intention to Purchase Products under Volume Discount Scheme: A Conceptual Model and Research Propositions

    Directory of Open Access Journals (Sweden)

    Mohammad Iranmanesh

    2014-12-01

    Full Text Available Many standard brands sell products under the volume discount scheme (VDS as more and more consumers are fond of purchasing products under this scheme. Despite volume discount being commonly practiced, there is a dearth of research, both conceptual and empirical, focusing on purchase characteristics factors and consumer internal evaluation concerning the purchase of products under VDS. To attempt to fill this void, this article develops a conceptual model on VDS with the intention of delineating the influence of the purchase characteristics factors on the consumer intention to purchase products under VDS and provides an explanation of their effects through consumer internal evaluation. Finally, the authors discuss the managerial implications of their research and offer guidelines for future empirical research.

  2. Documentation for grants equal to tax model: Volume 3, Source code

    International Nuclear Information System (INIS)

    Boryczka, M.K.

    1986-01-01

    The GETT model is capable of forecasting the amount of tax liability associated with all property owned and all activities undertaken by the US Department of Energy (DOE) in site characterization and repository development. The GETT program is a user-friendly, menu-driven model developed using dBASE III/trademark/, a relational data base management system. The data base for GETT consists primarily of eight separate dBASE III/trademark/ files corresponding to each of the eight taxes (real property, personal property, corporate income, franchise, sales, use, severance, and excise) levied by State and local jurisdictions on business property and activity. Additional smaller files help to control model inputs and reporting options. Volume 3 of the GETT model documentation is the source code. The code is arranged primarily by the eight tax types. Other code files include those for JURISDICTION, SIMULATION, VALIDATION, TAXES, CHANGES, REPORTS, GILOT, and GETT. The code has been verified through hand calculations

  3. A reaction-diffusion model for market fluctuations - A relation between price change and traded volumes

    Science.gov (United States)

    Yuvan, Steven; Bier, Martin

    2018-02-01

    Two decades ago Bak et al. (1997) [3] proposed a reaction-diffusion model to describe market fluctuations. In the model buyers and sellers diffuse from opposite ends of a 1D interval that represents a price range. Trades occur when buyers and sellers meet. We show analytically and numerically that the model well reproduces the square-root relation between traded volumes and price changes that is observed in real-life markets. The result is remarkable as this relation has commonly been explained in terms of more elaborate trader strategies. We furthermore explain why the square-root relation is robust under model modifications and we show how real-life bond market data exhibit the square-root relation.

  4. 3D robust Chan-Vese model for industrial computed tomography volume data segmentation

    Science.gov (United States)

    Liu, Linghui; Zeng, Li; Luan, Xiao

    2013-11-01

    Industrial computed tomography (CT) has been widely applied in many areas of non-destructive testing (NDT) and non-destructive evaluation (NDE). In practice, CT volume data to be dealt with may be corrupted by noise. This paper addresses the segmentation of noisy industrial CT volume data. Motivated by the research on the Chan-Vese (CV) model, we present a region-based active contour model that draws upon intensity information in local regions with a controllable scale. In the presence of noise, a local energy is firstly defined according to the intensity difference within a local neighborhood. Then a global energy is defined to integrate local energy with respect to all image points. In a level set formulation, this energy is represented by a variational level set function, where a surface evolution equation is derived for energy minimization. Comparative analysis with the CV model indicates the comparable performance of the 3D robust Chan-Vese (RCV) model. The quantitative evaluation also shows the segmentation accuracy of 3D RCV. In addition, the efficiency of our approach is validated under several types of noise, such as Poisson noise, Gaussian noise, salt-and-pepper noise and speckle noise.

  5. A Gaussian mixture model for definition of lung tumor volumes in positron emission tomography

    International Nuclear Information System (INIS)

    Aristophanous, Michalis; Penney, Bill C.; Martel, Mary K.; Pelizzari, Charles A.

    2007-01-01

    The increased interest in 18 F-fluorodeoxyglucose (FDG) positron emission tomography (PET) in radiation treatment planning in the past five years necessitated the independent and accurate segmentation of gross tumor volume (GTV) from FDG-PET scans. In some studies the radiation oncologist contours the GTV based on a computed tomography scan, while incorporating pertinent data from the PET images. Alternatively, a simple threshold, typically 40% of the maximum intensity, has been employed to differentiate tumor from normal tissue, while other researchers have developed algorithms to aid the PET based GTV definition. None of these methods, however, results in reliable PET tumor segmentation that can be used for more sophisticated treatment plans. For this reason, we developed a Gaussian mixture model (GMM) based segmentation technique on selected PET tumor regions from non-small cell lung cancer patients. The purpose of this study was to investigate the feasibility of using a GMM-based tumor volume definition in a robust, reliable and reproducible way. A GMM relies on the idea that any distribution, in our case a distribution of image intensities, can be expressed as a mixture of Gaussian densities representing different classes. According to our implementation, each class belongs to one of three regions in the image; the background (B), the uncertain (U) and the target (T), and from these regions we can obtain the tumor volume. User interaction in the implementation is required, but is limited to the initialization of the model parameters and the selection of an ''analysis region'' to which the modeling is restricted. The segmentation was developed on three and tested on another four clinical cases to ensure robustness against differences observed in the clinic. It also compared favorably with thresholding at 40% of the maximum intensity and a threshold determination function based on tumor to background image intensities proposed in a recent paper. The parts of the

  6. Predicting oropharyngeal tumor volume throughout the course of radiation therapy from pretreatment computed tomography data using general linear models

    International Nuclear Information System (INIS)

    Yock, Adam D.; Kudchadker, Rajat J.; Rao, Arvind; Dong, Lei; Beadle, Beth M.; Garden, Adam S.; Court, Laurence E.

    2014-01-01

    Purpose: The purpose of this work was to develop and evaluate the accuracy of several predictive models of variation in tumor volume throughout the course of radiation therapy. Methods: Nineteen patients with oropharyngeal cancers were imaged daily with CT-on-rails for image-guided alignment per an institutional protocol. The daily volumes of 35 tumors in these 19 patients were determined and used to generate (1) a linear model in which tumor volume changed at a constant rate, (2) a general linear model that utilized the power fit relationship between the daily and initial tumor volumes, and (3) a functional general linear model that identified and exploited the primary modes of variation between time series describing the changing tumor volumes. Primary and nodal tumor volumes were examined separately. The accuracy of these models in predicting daily tumor volumes were compared with those of static and linear reference models using leave-one-out cross-validation. Results: In predicting the daily volume of primary tumors, the general linear model and the functional general linear model were more accurate than the static reference model by 9.9% (range: −11.6%–23.8%) and 14.6% (range: −7.3%–27.5%), respectively, and were more accurate than the linear reference model by 14.2% (range: −6.8%–40.3%) and 13.1% (range: −1.5%–52.5%), respectively. In predicting the daily volume of nodal tumors, only the 14.4% (range: −11.1%–20.5%) improvement in accuracy of the functional general linear model compared to the static reference model was statistically significant. Conclusions: A general linear model and a functional general linear model trained on data from a small population of patients can predict the primary tumor volume throughout the course of radiation therapy with greater accuracy than standard reference models. These more accurate models may increase the prognostic value of information about the tumor garnered from pretreatment computed tomography

  7. New model for estimating the relationship between surface area and volume in the human body using skeletal remains.

    Science.gov (United States)

    Kasabova, Boryana E; Holliday, Trenton W

    2015-04-01

    A new model for estimating human body surface area and body volume/mass from standard skeletal metrics is presented. This model is then tested against both 1) "independently estimated" body surface areas and "independently estimated" body volume/mass (both derived from anthropometric data) and 2) the cylindrical model of Ruff. The model is found to be more accurate in estimating both body surface area and body volume/mass than the cylindrical model, but it is more accurate in estimating body surface area than it is for estimating body volume/mass (as reflected by the standard error of the estimate when "independently estimated" surface area or volume/mass is regressed on estimates derived from the present model). Two practical applications of the model are tested. In the first test, the relative contribution of the limbs versus the trunk to the body's volume and surface area is compared between "heat-adapted" and "cold-adapted" populations. As expected, the "cold-adapted" group has significantly more of its body surface area and volume in its trunk than does the "heat-adapted" group. In the second test, we evaluate the effect of variation in bi-iliac breadth, elongated or foreshortened limbs, and differences in crural index on the body's surface area to volume ratio (SA:V). Results indicate that the effects of bi-iliac breadth on SA:V are substantial, while those of limb lengths and (especially) the crural index are minor, which suggests that factors other than surface area relative to volume are driving morphological variation and ecogeographical patterning in limb prorportions. © 2014 Wiley Periodicals, Inc.

  8. The development of a volume element model for energy systems engineering and integrative thermodynamic optimization

    Science.gov (United States)

    Yang, Sam

    The dissertation presents the mathematical formulation, experimental validation, and application of a volume element model (VEM) devised for modeling, simulation, and optimization of energy systems in their early design stages. The proposed model combines existing modeling techniques and experimental adjustment to formulate a reduced-order model, while retaining sufficient accuracy to serve as a practical system-level design analysis and optimization tool. In the VEM, the physical domain under consideration is discretized in space using lumped hexahedral elements (i.e., volume elements), and the governing equations for the variable of interest are applied to each element to quantify diverse types of flows that cross it. Subsequently, a system of algebraic and ordinary differential equations is solved with respect to time and scalar (e.g., temperature, relative humidity, etc.) fields are obtained in both spatial and temporal domains. The VEM is capable of capturing and predicting dynamic physical behaviors in the entire system domain (i.e., at system level), including mutual interactions among system constituents, as well as with their respective surroundings and cooling systems, if any. The VEM is also generalizable; that is, the model can be easily adapted to simulate and optimize diverse systems of different scales and complexity and attain numerical convergence with sufficient accuracy. Both the capability and generalizability of the VEM are demonstrated in the dissertation via thermal modeling and simulation of an Off-Grid Zero Emissions Building, an all-electric ship, and a vapor compression refrigeration (VCR) system. Furthermore, the potential of the VEM as an optimization tool is presented through the integrative thermodynamic optimization of a VCR system, whose results are used to evaluate the trade-offs between various objective functions, namely, coefficient of performance, second law efficiency, pull-down time, and refrigerated space temperature, in

  9. Modeling the Interplay Between Tumor Volume Regression and Oxygenation in Uterine Cervical Cancer During Radiotherapy Treatment.

    Science.gov (United States)

    Belfatto, Antonella; Riboldi, Marco; Ciardo, Delia; Cattani, Federica; Cecconi, Agnese; Lazzari, Roberta; Jereczek-Fossa, Barbara Alicja; Orecchia, Roberto; Baroni, Guido; Cerveri, Pietro

    2016-03-01

    This paper describes a patient-specific mathematical model to predict the evolution of uterine cervical tumors at a macroscopic scale, during fractionated external radiotherapy. The model provides estimates of tumor regrowth and dead-cell reabsorption, incorporating the interplay between tumor regression rate and radiosensitivity, as a function of the tumor oxygenation level. Model parameters were estimated by minimizing the difference between predicted and measured tumor volumes, these latter being obtained from a set of 154 serial cone-beam computed tomography scans acquired on 16 patients along the course of the therapy. The model stratified patients according to two different estimated dynamics of dead-cell removal and to the predicted initial value of the tumor oxygenation. The comparison with a simpler model demonstrated an improvement in fitting properties of this approach (fitting error average value <5%, p < 0.01), especially in case of tumor late responses, which can hardly be handled by models entailing a constant radiosensitivity, failing to model changes from initial severe hypoxia to aerobic conditions during the treatment course. The model predictive capabilities suggest the need of clustering patients accounting for cancer cell line, tumor staging, as well as microenvironment conditions (e.g., oxygenation level).

  10. Development and Analysis of Volume Multi-Sphere Method Model Generation using Electric Field Fitting

    Science.gov (United States)

    Ingram, G. J.

    Electrostatic modeling of spacecraft has wide-reaching applications such as detumbling space debris in the Geosynchronous Earth Orbit regime before docking, servicing and tugging space debris to graveyard orbits, and Lorentz augmented orbits. The viability of electrostatic actuation control applications relies on faster-than-realtime characterization of the electrostatic interaction. The Volume Multi-Sphere Method (VMSM) seeks the optimal placement and radii of a small number of equipotential spheres to accurately model the electrostatic force and torque on a conducting space object. Current VMSM models tuned using force and torque comparisons with commercially available finite element software are subject to the modeled probe size and numerical errors of the software. This work first investigates fitting of VMSM models to Surface-MSM (SMSM) generated electrical field data, removing modeling dependence on probe geometry while significantly increasing performance and speed. A proposed electric field matching cost function is compared to a force and torque cost function, the inclusion of a self-capacitance constraint is explored and 4 degree-of-freedom VMSM models generated using electric field matching are investigated. The resulting E-field based VMSM development framework is illustrated on a box-shaped hub with a single solar panel, and convergence properties of select models are qualitatively analyzed. Despite the complex non-symmetric spacecraft geometry, elegantly simple 2-sphere VMSM solutions provide force and torque fits within a few percent.

  11. Final safety analysis report for the Galileo Mission: Volume 2, Book 2: Accident model document: Appendices

    Energy Technology Data Exchange (ETDEWEB)

    1988-12-15

    This section of the Accident Model Document (AMD) presents the appendices which describe the various analyses that have been conducted for use in the Galileo Final Safety Analysis Report II, Volume II. Included in these appendices are the approaches, techniques, conditions and assumptions used in the development of the analytical models plus the detailed results of the analyses. Also included in these appendices are summaries of the accidents and their associated probabilities and environment models taken from the Shuttle Data Book (NSTS-08116), plus summaries of the several segments of the recent GPHS safety test program. The information presented in these appendices is used in Section 3.0 of the AMD to develop the Failure/Abort Sequence Trees (FASTs) and to determine the fuel releases (source terms) resulting from the potential Space Shuttle/IUS accidents throughout the missions.

  12. Modelling of Evaporator in Waste Heat Recovery System using Finite Volume Method and Fuzzy Technique

    Directory of Open Access Journals (Sweden)

    Jahedul Islam Chowdhury

    2015-12-01

    Full Text Available The evaporator is an important component in the Organic Rankine Cycle (ORC-based Waste Heat Recovery (WHR system since the effective heat transfer of this device reflects on the efficiency of the system. When the WHR system operates under supercritical conditions, the heat transfer mechanism in the evaporator is unpredictable due to the change of thermo-physical properties of the fluid with temperature. Although the conventional finite volume model can successfully capture those changes in the evaporator of the WHR process, the computation time for this method is high. To reduce the computation time, this paper develops a new fuzzy based evaporator model and compares its performance with the finite volume method. The results show that the fuzzy technique can be applied to predict the output of the supercritical evaporator in the waste heat recovery system and can significantly reduce the required computation time. The proposed model, therefore, has the potential to be used in real time control applications.

  13. Modeling the spatial distribution of the parameters of the coolant in the reactor volume

    International Nuclear Information System (INIS)

    Nikonov, S.P.

    2011-01-01

    In this paper the approach to the question about the spatial distribution of the parameters of the coolant in-reactor volume. To describe the in-core space is used specially developed preprocessor. When the work of the preprocessor in the first place, is recreated on the basis of available information (mostly-the original drawings) with high accuracy three-dimensional description of the structures of the reactor volume and, secondly, are prepared on this basis blocks input to the nodal system code improved estimate ATHLET, allows to take into account the hydrodynamic interaction between the spatial control volumes. As an example the special case of solutions of international standard problem on the reconstruction of the transition process in the third unit of the Kalinin nuclear power plant, due to the shutdown of one of the four Main Coolant Pumps in operation at the rated capacity (first download). Model-core area consists of approximately 58 000 control volumes and spatial relationships. It shows the influence of certain structural units of the core to the distribution of the mass floe rate of its height. It is detected a strong cross-flow coolant in the area over the baffle. Moreover, we study the distribution of the coolant temperature at the assembly head of WWER-1000 reactor. It is shown that in the region of the top of the assembly head, where we have installation of thermocouples, the flow coolant for internal assemblies core is formed by only from guide channel Reactor control and protected system Control rod flow, or a mixture of the guide channel flow and flow from the area in front of top grid head assembly (the peripheral assemblies). It is shown that the magnitude of the flow guide channels affects not only the position of control rods, but also the presence of a particular type of measuring channels (Self powered neutron detector sensors or Temperature control sensors) in the cassette. (Author)

  14. Front tracking based modeling of the solid grain growth on the adaptive control volume grid

    Science.gov (United States)

    Seredyński, Mirosław; Łapka, Piotr

    2017-07-01

    The paper presents the micro-scale model of unconstrained solidification of the grain immersed in under-cooled liquid, based on the front tracking approach. For this length scale, the interface tracked through the domain is meant as the solid-liquid boundary. To prevent generation of huge meshes the energy transport equation is discretized on the adaptive control volume (c.v.) mesh. The coupling of dynamically changing mesh and moving front position is addressed. Preliminary results of simulation of a test case, the growth of single grain, are presented and discussed.

  15. Review of models used for determining consequences of UF6 release: Model evaluation report. Volume 2

    International Nuclear Information System (INIS)

    Nair, S.K.; Chambers, D.B.; Park, S.H.; Radonjic, Z.R.; Coutts, P.T.; Lewis, C.J.; Hammonds, J.S.; Hoffman, F.O.

    1997-11-01

    Three uranium hexafluoride-(UF 6 -) specific models--HGSYSTEM/UF 6 , Science Application International Corporation, and RTM-96; three dense-gas models--DEGADIS, SLAB, and the Chlorine Institute methodology; and one toxic chemical model--AFTOX--are evaluated on their capabilities to simulate the chemical reactions, thermodynamics, and atmospheric dispersion of UF 6 released from accidents at nuclear fuel-cycle facilities, to support Integrated Safety Analysis, Emergency Response Planning, and Post-Accident Analysis. These models are also evaluated for user-friendliness and for quality assurance and quality control features, to ensure the validity and credibility of the results. Model performance evaluations are conducted for the three UF 6 -specific models, using field data on releases of UF 6 and other heavy gases. Predictions from the HGSYSTEM/UF 6 and SAIC models are within an order of magnitude of the field data, but the SAIC model overpredicts beyond an order of magnitude for a few UF 6 -specific data points. The RTM-96 model provides overpredictions within a factor of 3 for all data points beyond 400 m from the source. For one data set, however, the RTM-96 model severely underpredicts the observations within 200 m of the source. Outputs of the models are most sensitive to the meteorological parameters at large distances from the source and to certain source-specific and meteorological parameters at distances close to the source. Specific recommendations are being made to improve the applicability and usefulness of the three models and to choose a specific model to support the intended analyses. Guidance is also provided on the choice of input parameters for initial dilution, building wake effects, and distance to completion of UF 6 reaction with water

  16. Preliminary thermal and thermomechanical modeling for the near surface test facility heater experiments at Hanford. Volume II: Appendix D

    International Nuclear Information System (INIS)

    Chan, T.; Remer, J.S.

    1978-12-01

    Appendix D is a complete set of figures illustrating the detailed calculations necessary for designing the heater experiments at the Near Surface Test Facility (NSTF) at Hanford, Washington. The discussion of the thermal and thermomechanical modeling that yielded these calculations is presented in Volume 1. A summary of the figures and the models they illustrate is given in table D1. The most important figures have also been included in the discussion in Volume 1, and Table D2 lists the figure numbers in this volume that correspond to figure numbers used there

  17. Natural Gas Transmission and Distribution Model of the National Energy Modeling System. Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-01-01

    The Natural Gas Transmission and Distribution Model (NGTDM) is the component of the National Energy Modeling System (NEMS) that is used to represent the domestic natural gas transmission and distribution system. The NGTDM is the model within the NEMS that represents the transmission, distribution, and pricing of natural gas. The model also includes representations of the end-use demand for natural gas, the production of domestic natural gas, and the availability of natural gas traded on the international market based on information received from other NEMS models. The NGTDM determines the flow of natural gas in an aggregate, domestic pipeline network, connecting domestic and foreign supply regions with 12 demand regions. The purpose of this report is to provide a reference document for model analysts, users, and the public that defines the objectives of the model, describes its basic design, provides detail on the methodology employed, and describes the model inputs, outputs, and key assumptions. Subsequent chapters of this report provide: an overview of NGTDM; a description of the interface between the NEMS and NGTDM; an overview of the solution methodology of the NGTDM; the solution methodology for the Annual Flow Module; the solution methodology for the Distributor Tariff Module; the solution methodology for the Capacity Expansion Module; the solution methodology for the Pipeline Tariff Module; and a description of model assumptions, inputs, and outputs.

  18. Documentation for Grants Equal to Tax model: Volume 1, Technical description

    International Nuclear Information System (INIS)

    1986-01-01

    A computerized model, the Grants Equal to Tax (GETT) model, was developed to assist in evaluating the amount of federal grant monies that would go to state and local jurisdictions under the provisions outlined in the Nuclear Waste Policy Act of 1982. The GETT model is capable of forecasting the amount of tax liability associated with all property owned and all activities undertaken by the US Department of Energy (DOE) in site characterization and repository development. The GETT program is a user-friendly, menu-driven model developed using dBASE III/trademark/, a relational data base management system. The data base for GETT consists primarily of eight separate dBASE III/trademark/ files corresponding to each of the eight taxes levied by state and local jurisdictions on business property and activity. Additional smaller files help to control model inputs and reporting options. Volume 1 of the GETT model documentation is a technical description of the program and its capabilities providing (1) descriptions of the data management system and its procedures; (2) formulas for calculating taxes (illustrated with flow charts); (3) descriptions of tax data base variables for the Deaf Smith County, Texas, Richton Dome, Mississippi, and Davis Canyon, Utah, salt sites; and (4) data inputs for the GETT model. 10 refs., 18 figs., 3 tabs

  19. A Volume-Fraction Based Two-Phase Constitutive Model for Blood

    Energy Technology Data Exchange (ETDEWEB)

    Zhao, Rui (Carnegie-Mellon Univ.); Massoudi, Mehrdad; Hund, S.J. (Carnegie-Mellon Univ.); •Antaki, J.F. (Carnegie-Mellon Univ.)

    2008-06-01

    Mechanically-induced blood trauma such as hemolysis and thrombosis often occurs at microscopic channels, steps and crevices within cardiovascular devices. A predictive mathematical model based on a broad understanding of hemodynamics at micro scale is needed to mitigate these effects, and is the motivation of this research project. Platelet transport and surface deposition is important in thrombosis. Microfluidic experiments have previously revealed a significant impact of red blood cell (RBC)-plasma phase separation on platelet transport [5], whereby platelet localized concentration can be enhanced due to a non-uniform distribution of RBCs of blood flow in a capillary tube and sudden expansion. However, current platelet deposition models either totally ignored RBCs in the fluid by assuming a zero sample hematocrit or treated them as being evenly distributed. As a result, those models often underestimated platelet advection and deposition to certain areas [2]. The current study aims to develop a two-phase blood constitutive model that can predict phase separation in a RBC-plasma mixture at the micro scale. The model is based on a sophisticated theory known as theory of interacting continua, i.e., mixture theory. The volume fraction is treated as a field variable in this model, which allows the prediction of concentration as well as velocity profiles of both RBC and plasma phases. The results will be used as the input of successive platelet deposition models.

  20. Geometry modeling and grid generation using 3D NURBS control volume

    Science.gov (United States)

    Yu, Tzu-Yi; Soni, Bharat K.; Shih, Ming-Hsin

    1995-01-01

    The algorithms for volume grid generation using NURBS geometric representation are presented. The parameterization algorithm is enhanced to yield a desired physical distribution on the curve, surface and volume. This approach bridges the gap between CAD surface/volume definition and surface/volume grid generation. Computational examples associated with practical configurations have shown the utilization of these algorithms.

  1. A Computational Model for the Automatic Diagnosis of Attention Deficit Hyperactivity Disorder Based on Functional Brain Volume

    Directory of Open Access Journals (Sweden)

    Lirong Tan

    2017-09-01

    Full Text Available In this paper, we investigated the problem of computer-aided diagnosis of Attention Deficit Hyperactivity Disorder (ADHD using machine learning techniques. With the ADHD-200 dataset, we developed a Support Vector Machine (SVM model to classify ADHD patients from typically developing controls (TDCs, using the regional brain volumes as predictors. Conventionally, the volume of a brain region was considered to be an anatomical feature and quantified using structural magnetic resonance images. One major contribution of the present study was that we had initially proposed to measure the regional brain volumes using fMRI images. Brain volumes measured from fMRI images were denoted as functional volumes, which quantified the volumes of brain regions that were actually functioning during fMRI imaging. We compared the predictive power of functional volumes with that of regional brain volumes measured from anatomical images, which were denoted as anatomical volumes. The former demonstrated higher discriminative power than the latter for the classification of ADHD patients vs. TDCs. Combined with our two-step feature selection approach which integrated prior knowledge with the recursive feature elimination (RFE algorithm, our SVM classification model combining functional volumes and demographic characteristics achieved a balanced accuracy of 67.7%, which was 16.1% higher than that of a relevant model published previously in the work of Sato et al. Furthermore, our classifier highlighted 10 brain regions that were most discriminative in distinguishing between ADHD patients and TDCs. These 10 regions were mainly located in occipital lobe, cerebellum posterior lobe, parietal lobe, frontal lobe, and temporal lobe. Our present study using functional images will likely provide new perspectives about the brain regions affected by ADHD.

  2. Transportation Sector Model of the National Energy Modeling System. Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-01-01

    This report documents the objectives, analytical approach and development of the National Energy Modeling System (NEMS) Transportation Model (TRAN). The report catalogues and describes the model assumptions, computational methodology, parameter estimation techniques, model source code, and forecast results generated by the model. The NEMS Transportation Model comprises a series of semi-independent models which address different aspects of the transportation sector. The primary purpose of this model is to provide mid-term forecasts of transportation energy demand by fuel type including, but not limited to, motor gasoline, distillate, jet fuel, and alternative fuels (such as CNG) not commonly associated with transportation. The current NEMS forecast horizon extends to the year 2010 and uses 1990 as the base year. Forecasts are generated through the separate consideration of energy consumption within the various modes of transport, including: private and fleet light-duty vehicles; aircraft; marine, rail, and truck freight; and various modes with minor overall impacts, such as mass transit and recreational boating. This approach is useful in assessing the impacts of policy initiatives, legislative mandates which affect individual modes of travel, and technological developments. The model also provides forecasts of selected intermediate values which are generated in order to determine energy consumption. These elements include estimates of passenger travel demand by automobile, air, or mass transit; estimates of the efficiency with which that demand is met; projections of vehicle stocks and the penetration of new technologies; and estimates of the demand for freight transport which are linked to forecasts of industrial output. Following the estimation of energy demand, TRAN produces forecasts of vehicular emissions of the following pollutants by source: oxides of sulfur, oxides of nitrogen, total carbon, carbon dioxide, carbon monoxide, and volatile organic compounds.

  3. Geoscience data base handbook for modeling a nuclear waste repository. Volume 1

    International Nuclear Information System (INIS)

    Isherwood, D.

    1979-12-01

    This handbook contains reference information on parameters that should be considered in analyzing or modeling a proposed nuclear waste repository site. Only those parameters and values that best represent the natural environment are included. Rare extremes are avoided. Where laboratory and field data are inadequate, theoretical treatments and informed engineering judgements are presented. Volume 1 contains a data base on salt as a repository medium. Chapters on the geology of bedded and dome salt, the geomechanics of salt, hydrology, geochemistry, natural and man-made features, and seismology provide compiled data and related information useful for studying a proposed repository in salt. These and other data will be needed to derive generic deep geologic modeling parameters and will also serve as background for the verification of source data that may be presented in licensing applications for nuclear waste repositories. Volume 2 is the result of a scoping study for a data base on the geology, geomechanics, and hydrology of shale, granite, and basalt as alternative repository media. Except for the geomechanics of shale, most of the sections contain relatively complete compilations of the available data, as well as discussions of the properties that are unique to each rock type

  4. Environmental fate model for ultra-low-volume insecticide applications used for adult mosquito management

    Science.gov (United States)

    Schleier, Jerome J.; Peterson, Robert K.D.; Irvine, Kathryn M.; Marshall, Lucy M.; Weaver, David K.; Preftakes, Collin J.

    2012-01-01

    One of the more effective ways of managing high densities of adult mosquitoes that vector human and animal pathogens is ultra-low-volume (ULV) aerosol applications of insecticides. The U.S. Environmental Protection Agency uses models that are not validated for ULV insecticide applications and exposure assumptions to perform their human and ecological risk assessments. Currently, there is no validated model that can accurately predict deposition of insecticides applied using ULV technology for adult mosquito management. In addition, little is known about the deposition and drift of small droplets like those used under conditions encountered during ULV applications. The objective of this study was to perform field studies to measure environmental concentrations of insecticides and to develop a validated model to predict the deposition of ULV insecticides. The final regression model was selected by minimizing the Bayesian Information Criterion and its prediction performance was evaluated using k-fold cross validation. Density of the formulation and the density and CMD interaction coefficients were the largest in the model. The results showed that as density of the formulation decreases, deposition increases. The interaction of density and CMD showed that higher density formulations and larger droplets resulted in greater deposition. These results are supported by the aerosol physics literature. A k-fold cross validation demonstrated that the mean square error of the selected regression model is not biased, and the mean square error and mean square prediction error indicated good predictive ability.

  5. Dose-volume effects in rat thoracolumbar spinal cord: an evaluation of NTCP models.

    Science.gov (United States)

    Philippens, Marielle E P; Pop, Lucas A M; Visser, Andries G; Schellekens, Suzanne A M W; van der Kogel, Albert J

    2004-10-01

    To evaluate models for normal-tissue-complication probability (NTCP) on describing the dose-volume effect in rat thoracolumbar spinal cord. Single-dose irradiation of four field lengths (4, 1.5, 1.0, and 0.5 cm) was evaluated by the endpoints paresis and white-matter necrosis. The resulting dose-response data were used to rank phenomenological and tissue architecture NTCP models. The 0.5-cm field length showed a steep increase in radiation tolerance. Statistical analysis of the model fits, which included evaluation of goodness of fit (GOF) and confidence intervals, resulted in the rejection of all the models considered. Excluding the smallest field length, the Schultheiss (D(50) = 21.5 Gy, k = 26.5), the relative seriality (D(50) = 21.4 Gy, s = 1.6, gamma(50) = 6.3), and the critical element (D(50,FSU) = 26.6 Gy, gamma(50,FSU) = 2.3, n = 1.3) model gave the best fit. A thorough statistical analysis resulted in a serial or critical-element behavior for the field lengths of 1.0 cm and greater. Including the 0.5-cm field length, the radiation response markedly diverged from serial properties, but none of the models applied acceptably described this dose-response relationship. This study suggests that the commonly assumed serial behavior of the spinal cord might be valid for daily use in external- beam irradiation.

  6. Mixed finite element - discontinuous finite volume element discretization of a general class of multicontinuum models

    Science.gov (United States)

    Ruiz-Baier, Ricardo; Lunati, Ivan

    2016-10-01

    We present a novel discretization scheme tailored to a class of multiphase models that regard the physical system as consisting of multiple interacting continua. In the framework of mixture theory, we consider a general mathematical model that entails solving a system of mass and momentum equations for both the mixture and one of the phases. The model results in a strongly coupled and nonlinear system of partial differential equations that are written in terms of phase and mixture (barycentric) velocities, phase pressure, and saturation. We construct an accurate, robust and reliable hybrid method that combines a mixed finite element discretization of the momentum equations with a primal discontinuous finite volume-element discretization of the mass (or transport) equations. The scheme is devised for unstructured meshes and relies on mixed Brezzi-Douglas-Marini approximations of phase and total velocities, on piecewise constant elements for the approximation of phase or total pressures, as well as on a primal formulation that employs discontinuous finite volume elements defined on a dual diamond mesh to approximate scalar fields of interest (such as volume fraction, total density, saturation, etc.). As the discretization scheme is derived for a general formulation of multicontinuum physical systems, it can be readily applied to a large class of simplified multiphase models; on the other, the approach can be seen as a generalization of these models that are commonly encountered in the literature and employed when the latter are not sufficiently accurate. An extensive set of numerical test cases involving two- and three-dimensional porous media are presented to demonstrate the accuracy of the method (displaying an optimal convergence rate), the physics-preserving properties of the mixed-primal scheme, as well as the robustness of the method (which is successfully used to simulate diverse physical phenomena such as density fingering, Terzaghi's consolidation

  7. International Nuclear Model. Volume 3. Program description. Appendix A-H (Part 1)

    International Nuclear Information System (INIS)

    Andress, D.

    1985-01-01

    The International Nuclear Model (INM) is a comprehensive model of the commercial nuclear power industry. It simulates economic decisions for reactor deployment and fuel management decisions based on an input set of technical, economic and scenario parameters. The technical parameters include reactor operating characteristics, fuel cycle timing and mass loss factors, and enrichment tails assays. Economic parameters include fuel cycle costs, financial data, and tax alternatives. INM has a broad range of scenario options covering, for example, process constraints, interregional activities, reprocessing, and fuel management selection. INM reports reactor deployment schedules, electricity generation, and fuel cycle requirements and costs. It also has specialized reports for extended burnup and permanent disposal. This volume contains appendices A through H including a description of subroutines and the Fortran listing of the program

  8. Numerical Modeling of Poroelastic-Fluid Systems Using High-Resolution Finite Volume Methods

    Science.gov (United States)

    Lemoine, Grady

    Poroelasticity theory models the mechanics of porous, fluid-saturated, deformable solids. It was originally developed by Maurice Biot to model geophysical problems, such as seismic waves in oil reservoirs, but has also been applied to modeling living bone and other porous media. Poroelastic media often interact with fluids, such as in ocean bottom acoustics or propagation of waves from soft tissue into bone. This thesis describes the development and testing of high-resolution finite volume numerical methods, and simulation codes implementing these methods, for modeling systems of poroelastic media and fluids in two and three dimensions. These methods operate on both rectilinear grids and logically rectangular mapped grids. To allow the use of these methods, Biot's equations of poroelasticity are formulated as a first-order hyperbolic system with a source term; this source term is incorporated using operator splitting. Some modifications are required to the classical high-resolution finite volume method. Obtaining correct solutions at interfaces between poroelastic media and fluids requires a novel transverse propagation scheme and the removal of the classical second-order correction term at the interface, and in three dimensions a new wave limiting algorithm is also needed to correctly limit shear waves. The accuracy and convergence rates of the methods of this thesis are examined for a variety of analytical solutions, including simple plane waves, reflection and transmission of waves at an interface between different media, and scattering of acoustic waves by a poroelastic cylinder. Solutions are also computed for a variety of test problems from the computational poroelasticity literature, as well as some original test problems designed to mimic possible applications for the simulation code.

  9. Mass residuals in implicit finite volume models for overland and groundwater flow

    Science.gov (United States)

    Lal, A. M. Wasantha; Wang, Naming; Moustafa, M. Z.; Brown, M. C.

    2010-04-01

    SummaryA primary advantage in using the finite volume method for simulating groundwater flow and overland flow is the conservation property or the ability to conserve mass. However, when implicit finite volume methods are used with large time steps, small cell areas, or parameters with extreme value ranges, the conservation of mass equation becomes slightly unbalanced with a residual. Problems with large mass residuals can be predicted using the condition number of the solution matrix, and the convergence criterion used in the sparse matrix solver. The amount of practical guidance available on how to manage the magnitude of the mass residual or the matrix condition number is limited. To address this need, the current paper shows the usefulness of the mesh ratio. The mesh ratio is a dimensionless number that is a function of the mesh resolution and the temporal resolution. It is directly related to the condition number of the matrix, which in turn affects the mass residual and the model run time. During the current study, several numerical experiments are carried out to determine how the mesh ratio and the water level are related to the condition number, how the critical mesh ratio is related to the number of cells, how the run time is related to the mesh ratio, and how the mass residual is related to the mesh ratio. The results are useful in creating guidelines for mesh design during large-scale model applications. These guidelines can be applied to reducing the mass residual and the run time. The usefulness of the mesh ratio is illustrated using a Regional Simulation Model (RSM) (Lal, A.M.W., Van Zee, Randy, Belnap, Mark, 2005. Case study: model to simulate regional flow in South Florida. Journal of Hydraulic Engineering 131 (4), 247-258) application in south Florida.

  10. Does amniotic fluid volume affect fetofetal transfusion in monochorionic twin pregnancies? Modelling two possible mechanisms

    Science.gov (United States)

    Umur, Asli; van Gemert, Martin J. C.; Ross, Michael G.

    2002-06-01

    Clinical evidence suggests that increased amniotic fluid volume due to polyhydramnios increases placental vascular resistance. We have sought to model the possible effects of an increased amniotic fluid volume on the net fetofetal transfusion in monochorionic twin pregnancies. We wanted to compare these effects with the results of previous simulations, which aimed to explain why the twin-twin transfusion syndrome (TTTS) placentas more often include bidirectional arteriovenous (AV) rather than AV plus arterioarterial (AA) anastomoses. We extended our mathematical model of TTTS by simulating two different mechanisms that increase the placental vascular resistance as a consequence of polyhydramnios. First, there is an increase in the placental capillary resistance and hence in deep AV and opposite AV (denoted as VA) resistances due to polyhydramnios. Second, there is an increase in the resistance of chorionic veins due to polyhydramnios, assuming that these veins act as Starling resistors. We then simulated the effects of polyhydramnios on different placental anastomotic patterns. The results were as follows. In the first mechanism (polyhydramnios affects AV-VA resistances), an increased amniotic fluid volume hardly affected bidirectional AV, but slightly decreased fetofetal transfusion in AV plus AA anastomoses. However, for these effects to change the natural development of the pregnancy, polyhydramnios needed to persist for approximately 4 weeks, and by comparing the effects of polyhydramnios with the effects of amnioreduction, amnioreduction was more beneficial for normalizing the donor amniotic fluid volume. Therefore, these beneficial effects due to polyhydramnios have no practical clinical significance. In the second mechanism (Starling resistor for chorionic veins), polyhydramnios slightly increased fetofetal transfusion and hence slightly increased TTTS severity in bidirectional AV and AV plus VV, but did not affect AV plus AA anastomoses. In conclusion, we

  11. EOS simulation and GRNN modeling of the constant volume depletion behavior of gas condensate reservoirs

    Energy Technology Data Exchange (ETDEWEB)

    Elsharkawy, A.M.; Foda, S.G. [Kuwait University, Safat (Kuwait). Petroleum Engineering Dept.

    1998-03-01

    Currently, two approaches are being used to predict the changes in retrograde gas condensate composition and estimate the pressure depletion behavior of gas condensate reservoirs. The first approach uses the equation of states whereas the second uses empirical correlations. Equations of states (EOS) are poor predictive tools for complex hydrocarbon systems. The EOS needs adjustment against phase behavior data of reservoir fluid of known composition. The empirical correlation does not involve numerous numerical computations but their accuracy is limited. This study presents two general regression neural network (GRNN) models. The first model, GRNNM1, is developed to predict dew point pressure and gas compressibility at dew point using initial composition of numerous samples while the second model, GRNNM2, is developed to predict the changes in well stream effluent composition at any stages of pressure depletion. GRNNM2 can also be used to determine the initial reservoir fluid composition using dew point pressure, gas compressibility at dew point, and reservoir temperature. These models are based on analysis of 142 sample of laboratory studies of constant volume depletion (CVD) for gas condensate systems forming a total of 1082 depletion stages. The database represents a wide range of gas condensate systems obtained worldwide. The performance of the GRNN models has been compared to simulation results of the equation of state. The study shows that the proposed general regression neural network models are accurate, valid, and reliable. These models can be used to forecast CVD data needed for many reservoir engineering calculations in case laboratory data is unavailable. The GRNN models save computer time involved in EOS calculations. The study also show that once these models are properly trained they can be used to cut expenses of frequent sampling and laborious experimental CVD tests required for gas condensate reservoirs. 55 refs., 13 figs., 6 tabs.

  12. Thermal Pollution Mathematical Model. Volume 2; Verification of One-Dimensional Numerical Model at Lake Keowee

    Science.gov (United States)

    Lee, S. S.; Sengupta, S.; Nwadike, E. V.

    1980-01-01

    A one dimensional model for studying the thermal dynamics of cooling lakes was developed and verified. The model is essentially a set of partial differential equations which are solved by finite difference methods. The model includes the effects of variation of area with depth, surface heating due to solar radiation absorbed at the upper layer, and internal heating due to the transmission of solar radiation to the sub-surface layers. The exchange of mechanical energy between the lake and the atmosphere is included through the coupling of thermal diffusivity and wind speed. The effects of discharge and intake by power plants are also included. The numerical model was calibrated by applying it to Cayuga Lake. The model was then verified through a long term simulation using Lake Keowee data base. The comparison between measured and predicted vertical temperature profiles for the nine years is good. The physical limnology of Lake Keowee is presented through a set of graphical representations of the measured data base.

  13. SCDAP/RELAP5/MOD 3.1 code manual: Damage progression model theory. Volume 2

    Energy Technology Data Exchange (ETDEWEB)

    Davis, K.L. [ed.; Allison, C.M.; Berna, G.A. [Lockheed Idaho Technologies Co., Idaho Falls, ID (United States)] [and others

    1995-06-01

    The SCDAP/RELAP5 code has been developed for best estimate transient simulation of light water reactor coolant systems during a severe accident. The code models the coupled behavior of the reactor coolant system, the core, fission products released during a severe accident transient as well as large and small break loss of coolant accidents, operational transients such as anticipated transient without SCRAM, loss of offsite power, loss of feedwater, and loss of flow. A generic modeling approach is used that permits as much of a particular system to be modeled as necessary. Control system and secondary system components are included to permit modeling of plant controls, turbines, condensers, and secondary feedwater conditioning systems. This volume contains detailed descriptions of the severe accident models and correlations. It provides the user with the underlying assumptions and simplifications used to generate and implement the basic equations into the code, so an intelligent assessment of the applicability and accuracy of the resulting calculation can be made.

  14. SCDAP/RELAP5/MOD 3.1 code manual: Damage progression model theory. Volume 2

    International Nuclear Information System (INIS)

    Davis, K.L.

    1995-06-01

    The SCDAP/RELAP5 code has been developed for best estimate transient simulation of light water reactor coolant systems during a severe accident. The code models the coupled behavior of the reactor coolant system, the core, fission products released during a severe accident transient as well as large and small break loss of coolant accidents, operational transients such as anticipated transient without SCRAM, loss of offsite power, loss of feedwater, and loss of flow. A generic modeling approach is used that permits as much of a particular system to be modeled as necessary. Control system and secondary system components are included to permit modeling of plant controls, turbines, condensers, and secondary feedwater conditioning systems. This volume contains detailed descriptions of the severe accident models and correlations. It provides the user with the underlying assumptions and simplifications used to generate and implement the basic equations into the code, so an intelligent assessment of the applicability and accuracy of the resulting calculation can be made

  15. Alligator Rivers Analogue project. Geochemical modelling of secondary uranium ore formation. Final Report - Volume 11

    International Nuclear Information System (INIS)

    Sverjensky, D.; Bennett, D.G.; Read, D.

    1992-01-01

    The purpose of the present study was to establish how the uranyl phosphate zone at the Koongarra site was formed. The overall approach taken in the present study employed theoretical chemical mass transfer calculations and models that permit investigation and reconstruction of the kinds of waters that could produce the uranyl phosphate zone. These calculations have used the geological and mineralogical data for the Koongarra weathered zone (Volumes 2, 8, and 9 of this series), to constrain the initial compositions and reactions undergone by groundwater during the formation of the uranyl phosphate zone. In carrying out these calculations the present-day analyses of Koongarra waters are used only as a guide to the possible initial composition of the fluids associated with the formation of the phosphate zone. Aqueous speciation, saturation state and chemical mass transfer calculations were carried out using the computer programs EQ3NR and EQ6 (Wolery, 1983; Wolery et al., 1984) and a thermodynamic database generated at The Johns Hopkins University over the last eight years which is tabulated in the Appendix 1 to Volume 12 of this series. Despite uncertainties in the thermodynamic characterisation of species, all the above calculations suggest that the uranyl phosphate zone at Koongarra has not formed from present-day groundwaters (Volume 12 of this series). The present-day groundwaters in the weathered zone (eg. at 13 m depth) appear to be undersaturated with respect to saleeite. Furthermore, as present-day groundwaters descend below the water table they rapidly lose their atmospheric oxygen imprint, as is typical of most groundwaters, and become even more reducing in character. Under these circumstances, the groundwaters become more undersaturated with respect to saleeite than the shallow groundwaters. Because much of the phosphate zone is currently below the water table, under saturated zone conditions, it is suggested in the present study that the uranyl phosphate

  16. Glacier volume response time and its links to climate and topography based on a conceptual model of glacier hypsometry

    Directory of Open Access Journals (Sweden)

    S. C. B. Raper

    2009-08-01

    Full Text Available Glacier volume response time is a measure of the time taken for a glacier to adjust its geometry to a climate change. It has been previously proposed that the volume response time is given approximately by the ratio of glacier thickness to ablation at the glacier terminus. We propose a new conceptual model of glacier hypsometry (area-altitude relation and derive the volume response time where climatic and topographic parameters are separated. The former is expressed by mass balance gradients which we derive from glacier-climate modelling and the latter are quantified with data from the World Glacier Inventory. Aside from the well-known scaling relation between glacier volume and area, we establish a new scaling relation between glacier altitude range and area, and evaluate it for seven regions. The presence of this scaling parameter in our response time formula accounts for the mass balance elevation feedback and leads to longer response times than given by the simple ratio of glacier thickness to ablation at the terminus. Volume response times range from decades to thousands of years for glaciers in maritime (wet-warm and continental (dry-cold climates respectively. The combined effect of volume-area and altitude-area scaling relations is such that volume response time can increase with glacier area (Axel Heiberg Island and Svalbard, hardly change (Northern Scandinavia, Southern Norway and the Alps or even get smaller (The Caucasus and New Zealand.

  17. Limitations and pitfalls in measurements of right ventricular stroke volume in an animal model of right heart failure

    International Nuclear Information System (INIS)

    Vildbrad, Mads Dam; Andersen, Asger; Andersen, Thomas Krarup; Axelgaard, Sofie; Holmboe, Sarah; Andersen, Stine; Nielsen-Kudsk, Jens Erik; Ringgaard, Steffen

    2015-01-01

    Right heart failure occurs in various heart and pulmonary vascular diseases and may be fatal. We aimed to identify limitations in non-invasive measurements of right ventricular stroke volume in an animal model of right ventricular failure. Data from previous studies randomising rats to pulmonary trunk banding (PTB, n = 33) causing pressure-overload right ventricular failure or sham operation (n = 16) was evaluated retrospectively. We measured right ventricular stroke volume by high frequency echocardiography and magnetic resonance imaging (MRI). We found correlation between right ventricular stroke volume measured by echocardiography and MRI in the sham animals (r = 0.677, p = 0.004) but not in the PTB group. Echocardiography overestimated the stroke volume compared to MRI in both groups. Intra- and inter-observer variation did not explain the difference. Technical, physiological and anatomical issues in the pulmonary artery might explain why echocardiography over-estimates stroke volume. Flow acceleration close to the pulmonary artery banding can cause uncertainties in the PTB model and might explain the lack of correlation. In conclusion, we found a correlation in right ventricular stroke volume measured by echocardiography versus MRI in the sham group but not the PTB group. Echocardiography overestimated right ventricular stroke volume compared to MRI. (paper)

  18. Effect of the spray volume adjustment model on the efficiency of fungicides and residues in processing tomato

    Directory of Open Access Journals (Sweden)

    Henryk Ratajkiewicz

    2016-08-01

    Full Text Available This study compared the effects of a proportionate spray volume (PSV adjustment model and a fixed model (300 L/ha on the infestation of processing tomato with potato late blight (Phytophthora infestans (Mont. de Bary (PLB and azoxystrobin and chlorothalonil residues in fruits in three consecutive seasons. The fungicides were applied in alternating system with or without two spreader adjuvants. The proportionate spray volume adjustment model was based on the number of leaves on plants and spray volume index. The modified Quick, Easy, Cheap, Effective, Rugged, and Safe (QuEChERS method was optimized and validated for extraction of azoxystrobin and chlorothalonil residue. Gas chromatography with a nitrogen and phosphorus detector and an electron capture detector were used for the analysis of fungicides. The results showed that higher fungicidal residues were connected with lower infestation of tomato with PLB. PSV adjustment model resulted in lower infestation of tomato than the fixed model (300 L/ha when fungicides were applied at half the dose without adjuvants. Higher expected spray interception into the tomato canopy with the PSV system was recognized as the reasons of better control of PLB. The spreader adjuvants did not have positive effect on the biological efficacy of spray volume application systems. The results suggest that PSV adjustment model can be used to determine the spray volume for fungicide application for processing tomato crop.

  19. Effect of the spray volume adjustment model on the efficiency of fungicides and residues in processing tomato

    Energy Technology Data Exchange (ETDEWEB)

    Ratajkiewicz, H.; Kierzek, R.; Raczkowski, M.; Hołodyńska-Kulas, A.; Łacka, A.; Wójtowicz, A.; Wachowiak, M.

    2016-11-01

    This study compared the effects of a proportionate spray volume (PSV) adjustment model and a fixed model (300 L/ha) on the infestation of processing tomato with potato late blight (Phytophthora infestans (Mont.) de Bary) (PLB) and azoxystrobin and chlorothalonil residues in fruits in three consecutive seasons. The fungicides were applied in alternating system with or without two spreader adjuvants. The proportionate spray volume adjustment model was based on the number of leaves on plants and spray volume index. The modified Quick, Easy, Cheap, Effective, Rugged, and Safe (QuEChERS) method was optimized and validated for extraction of azoxystrobin and chlorothalonil residue. Gas chromatography with a nitrogen and phosphorus detector and an electron capture detector were used for the analysis of fungicides. The results showed that higher fungicidal residues were connected with lower infestation of tomato with PLB. PSV adjustment model resulted in lower infestation of tomato than the fixed model (300 L/ha) when fungicides were applied at half the dose without adjuvants. Higher expected spray interception into the tomato canopy with the PSV system was recognized as the reasons of better control of PLB. The spreader adjuvants did not have positive effect on the biological efficacy of spray volume application systems. The results suggest that PSV adjustment model can be used to determine the spray volume for fungicide application for processing tomato crop. (Author)

  20. 2D-3D Registration of CT Vertebra Volume to Fluoroscopy Projection: A Calibration Model Assessment

    Directory of Open Access Journals (Sweden)

    P. Bifulco

    2010-01-01

    Full Text Available This study extends a previous research concerning intervertebral motion registration by means of 2D dynamic fluoroscopy to obtain a more comprehensive 3D description of vertebral kinematics. The problem of estimating the 3D rigid pose of a CT volume of a vertebra from its 2D X-ray fluoroscopy projection is addressed. 2D-3D registration is obtained maximising a measure of similarity between Digitally Reconstructed Radiographs (obtained from the CT volume and real fluoroscopic projection. X-ray energy correction was performed. To assess the method a calibration model was realised a sheep dry vertebra was rigidly fixed to a frame of reference including metallic markers. Accurate measurement of 3D orientation was obtained via single-camera calibration of the markers and held as true 3D vertebra position; then, vertebra 3D pose was estimated and results compared. Error analysis revealed accuracy of the order of 0.1 degree for the rotation angles of about 1 mm for displacements parallel to the fluoroscopic plane, and of order of 10 mm for the orthogonal displacement.

  1. Streaming Model Based Volume Ray Casting Implementation for Cell Broadband Engine

    Directory of Open Access Journals (Sweden)

    Jusub Kim

    2009-01-01

    Full Text Available Interactive high quality volume rendering is becoming increasingly more important as the amount of more complex volumetric data steadily grows. While a number of volumetric rendering techniques have been widely used, ray casting has been recognized as an effective approach for generating high quality visualization. However, for most users, the use of ray casting has been limited to datasets that are very small because of its high demands on computational power and memory bandwidth. However the recent introduction of the Cell Broadband Engine (Cell B.E. processor, which consists of 9 heterogeneous cores designed to handle extremely demanding computations with large streams of data, provides an opportunity to put the ray casting into practical use. In this paper, we introduce an efficient parallel implementation of volume ray casting on the Cell B.E. The implementation is designed to take full advantage of the computational power and memory bandwidth of the Cell B.E. using an intricate orchestration of the ray casting computation on the available heterogeneous resources. Specifically, we introduce streaming model based schemes and techniques to efficiently implement acceleration techniques for ray casting on Cell B.E. In addition to ensuring effective SIMD utilization, our method provides two key benefits: there is no cost for empty space skipping and there is no memory bottleneck on moving volumetric data for processing. Our experimental results show that we can interactively render practical datasets on a single Cell B.E. processor.

  2. THE USE OF DYNAMIC MODELS OF CAR TRAFFIC VOLUME PROMOTION IN TECHNICAL REGULATION

    Directory of Open Access Journals (Sweden)

    V. H. Kuznetsov

    2007-08-01

    Full Text Available Modern lines in the field of transport management are directed on transition from analytical systems of processing of information to the information-operating systems providing support of decision-making in management by transportations. New conditions of managing, on the one hand, and development of the automated systems of gathering and processing of information in transport industry, on the other hand, allows to reach essentially new level of planning the parameters of transport operation with development of new methodology of solution of the given problems. The creation of dynamic model of promotion of traffic volumes is one of the new methods that allows solving a number of operational problems.. In the paper the mathematical description of range of a network and dynamic model is given. The concept of individual transportation is presented, classification of dynamic models depending on the initial information is given. Mathematical study and algorithm of construction of dynamic models enables their applications for solution of wide range of problems on transport.

  3. Control-volume-based model of the steam-water injector flow

    Science.gov (United States)

    Kwidziński, Roman

    2010-03-01

    The paper presents equations of a mathematical model to calculate flow parameters in characteristic cross-sections in the steam-water injector. In the model, component parts of the injector (steam nozzle, water nozzle, mixing chamber, condensation wave region, diffuser) are treated as a series of connected control volumes. At first, equations for the steam nozzle and water nozzle are written and solved for known flow parameters at the injector inlet. Next, the flow properties in two-phase flow comprising mixing chamber and condensation wave region are determined from mass, momentum and energy balance equations. Then, water compression in diffuser is taken into account to evaluate the flow parameters at the injector outlet. Irreversible losses due to friction, condensation and shock wave formation are taken into account for the flow in the steam nozzle. In two-phase flow domain, thermal and mechanical nonequilibrium between vapour and liquid is modelled. For diffuser, frictional pressure loss is considered. Comparison of the model predictions with experimental data shows good agreement, with an error not exceeding 15% for discharge (outlet) pressure and 1 K for outlet temperature.

  4. Black liquor combustion validated recovery boiler modeling: Final year report. Volume 4 (Appendix IV)

    Energy Technology Data Exchange (ETDEWEB)

    Grace, T.M.; Frederick, W.J.; Salcudean, M.; Wessel, R.A.

    1998-08-01

    This project was initiated in October 1990, with the objective of developing and validating a new computer model of a recovery boiler furnace using a computational fluid dynamics (CFD) code specifically tailored to the requirements for solving recovery boiler flows, and using improved submodels for black liquor combustion based on continued laboratory fundamental studies. The key tasks to be accomplished were as follows: (1) Complete the development of enhanced furnace models that have the capability to accurately predict carryover, emissions behavior, dust concentrations, gas temperatures, and wall heat fluxes. (2) Validate the enhanced furnace models, so that users can have confidence in the predicted results. (3) Obtain fundamental information on aerosol formation, deposition, and hardening so as to develop the knowledge base needed to relate furnace model outputs to plugging and fouling in the convective sections of the boiler. (4) Facilitate the transfer of codes, black liquid submodels, and fundamental knowledge to the US kraft pulp industry. Volume 4 contains the following appendix sections: Radiative heat transfer properties for black liquor combustion -- Facilities and techniques and Spectral absorbance and emittance data; and Radiate heat transfer determination of the optical constants of ash samples from kraft recovery boilers -- Calculation procedure; Computation program; Density determination; Particle diameter determination; Optical constant data; and Uncertainty analysis.

  5. Modeling oil spills transportation in seas based on unstructured grid, finite-volume, wave-ocean model

    Science.gov (United States)

    Wang, Jinhua; Shen, Yongming

    A three-dimensional integrated model is developed for simulating transport and fate of oil spills in seas. The model contains two main modules, flow and transport-fate modules. The flow module uses an unstructured finite-volume wave-ocean coupling model. Using unstructured meshes provides great flexibility for modeling the flow in complex geometries of tidal creeks, barriers and islands, with refined grid resolution in regions of interest and not elsewhere. In the transport-fate module the oil dispersion is solved using a particle-tracking method. Horizontal diffusion is simulated using random walk techniques in a Monte Carlo framework, whereas the vertical diffusion process is solved on the basis of the Langeven equation. The model simulates the most significant processes that affect the motion of oil particles, such as advection, surface spreading, evaporation, dissolution, emulsification and turbulent diffusion as well as the interaction of the oil particles with the shoreline, sedimentation and the temporal variations of oil viscosity, density and surface-tension. Detailed comparisons of simulations with analytical solutions and numerical simulations made with the popular structured finite difference model ROMS (the Regional Ocean Modeling System) for two idealized cases: wind-induced long-surface gravity waves in a circular lake and freshwater discharge onto the continental shelf with curved coastlines, are presented. With a better fit to the curvature of the coastline using unstructured nonoverlapping triangle grid cells, the developed model system provides improved numerical accuracy in simulating the oil spill trajectory. Also keep in mind that attention must be paid to choose the horizontal and vertical resolution in simulating the oil trajectory in the coastal ocean.

  6. Integrating model of the Project Independence Evaluation System. Volume V. Code documentation

    Energy Technology Data Exchange (ETDEWEB)

    Shaw, M L; Allen, B J; Lutz, M S; Gale, J E; O& #x27; Hara, N E; Wood, R K

    1978-07-01

    This volume is a description of the Project Independence Evaluation System as a computer system. It is intended for readers wanting a basic understanding of the computer implementation of PIES rather than an understanding of the modeling methodology. It can assist those who wish to run PIES on the EIA computer facility or to use PIES on their own facilities, or to analyze the PIES computer processing. The document contains: an overview of the computer implementation; a description of the data and naming conventions used in PIES; a functional description of PIES data processing; PIES hardware and software requirements; and an operational description of the PIES processing flow. This overview defines the scope of PIES in this report and thus governs the computer system descriptions that follow. It also provides an historical view of the development of PIES.

  7. Constitutive Modelling in Thermomechanical Processes, Using The Control Volume Method on Staggered Grid

    DEFF Research Database (Denmark)

    Thorborg, Jesper

    -strain relation has been suggested. The intention of this method is to provide fast numerical results with reasonable accuracy in relation to the first order effects of the presented classical plasticity model. Application of the $J_2$ flow theory and the alternative method have shown some agreement...... of the method has been focused on high temperature processes such as casting and welding and the interest of using nonlinear constitutive stress-strain relations has grown to extend the applicability of the method. The work of implementing classical plasticity into the control volume formulation has been based...... on the $J_2$ flow theory describing an isotropic hardening material with a temperature dependent yield stress. This work has successfully been verified by comparing results to analytical solutions. Due to the comprehensive implementation in the staggered grid an alternative constitutive stress...

  8. Stress/strain Modelling of Casting Processes in the Framework of the Control-Volume Method

    DEFF Research Database (Denmark)

    Hattel, Jesper Henri; Thorborg, Jesper; Andersen, Søren

    1998-01-01

    Realistic computer simulations of casting processes call for the solution of both thermal, fluid-flow and stress/strain related problems. The multitude of the influencing parameters, and their non-linear, transient and temperature dependent nature, make the calculations complex. Therefore the need......, the present model is based on the mainly decoupled representation of the thermal, mechanical and microstructural processes. Examples of industrial applications, such as predicting residual deformations in castings and stress levels in die casting dies, are presented...... domain, which is highly convenient. The basis of the method is the control volume finite difference approach on structured meshes. The basic assumptions of the method are shortly reviewed and discussed. As for other methods which aim at application oriented analysis of casting deformations and stresses...

  9. External field effects on diffusion and solidification derived from the free-volume model

    Science.gov (United States)

    Miller, R. I.; Ruff, R. C.

    1975-01-01

    Expressions for the diffusion coefficient and the solidification rate from the free-volume model of liquids developed by Turnbull and Cohen have been used to estimate the effects which microgravity and magnetic fields will have on these quantities. The mathematical formalism describing changes of the diffusion coefficient and the solidification rate is the same for both the microgravity and magnetic field cases, but the difference between the magnitudes of the two effects is quite large. The change in the two parameters is found to be less than .0001% for the microgravity case and on the order of 0.1 to 1.1% for the magnetic field case for four representative materials. The diffusion coefficient and the solidification rate are found to increase under the influence of an applied magnetic field, and this is in agreement with experimental observations.

  10. Hyperbolic reformulation of a 1D viscoelastic blood flow model and ADER finite volume schemes

    International Nuclear Information System (INIS)

    Montecinos, Gino I.; Müller, Lucas O.; Toro, Eleuterio F.

    2014-01-01

    The applicability of ADER finite volume methods to solve hyperbolic balance laws with stiff source terms in the context of well-balanced and non-conservative schemes is extended to solve a one-dimensional blood flow model for viscoelastic vessels, reformulated as a hyperbolic system, via a relaxation time. A criterion for selecting relaxation times is found and an empirical convergence rate assessment is carried out to support this result. The proposed methodology is validated by applying it to a network of viscoelastic vessels for which experimental and numerical results are available. The agreement between the results obtained in the present paper and those available in the literature is satisfactory. Key features of the present formulation and numerical methodologies, such as accuracy, efficiency and robustness, are fully discussed in the paper

  11. Simultaneous free-volume modeling of the self-diffusion coefficient and dynamic viscosity at high pressure

    DEFF Research Database (Denmark)

    Boned, C.; Allal, A.; Baylaucq, A.

    2004-01-01

    In this work, a simultaneous modeling of the self-diffusion coefficient and the dynamic viscosity is presented. In the microstructural theory these two quantities are governed by the same friction coefficient related to the mobility of the molecule. A recent free-volume model, already successfully...

  12. Building generalized tree mass/volume component models for improved estimation of forest stocks and utilization potential

    Science.gov (United States)

    David W. MacFarlane

    2015-01-01

    Accurately assessing forest biomass potential is contingent upon having accurate tree biomass models to translate data from forest inventories. Building generality into these models is especially important when they are to be applied over large spatial domains, such as regional, national and international scales. Here, new, generalized whole-tree mass / volume...

  13. Pore-to-Darcy Scale Hybrid Multiscale Finite Volume Model for Reactive Flow and Transport

    Science.gov (United States)

    Barajas-Solano, D. A.; Tartakovsky, A. M.

    2016-12-01

    In the present work we develop a hybrid scheme for the coupling and temporal integration of grid-based, continuum models for pore-scale and Darcy-scale flow and reactive transport. The hybrid coupling strategy consists on applying Darcy-scale and pore-scale flow and reactive transport models over overlapping subdomains Ω C and Ω F, and enforcing continuity of state and fluxes by means of restriction and prolongation operations defined over the overlap subdomain Ω hs ≡ Ω C \\cap Ω F. For the pore-scale model, we use a Multiscale Finite Volume (MsFV) characterization of the pore-scale state in terms of Darcy-scale degrees of freedom and local functions defined as the solution of pore-scale problems. The hybrid MsFV coupling results in a local-global combination of effective mass balance relations for the Darcy-scale degrees of freedom and local problems for the pore-scale degrees of freedom that capture pore-scale behavior. Our scheme allows for the rapid coarsening of pore-scale models and the adaptive enrichment of Darcy-scale models with pore-scale information. Additionally, we propose a strategy for modeling the dynamics of the pore-scale solid-liquid boundary due to precipitation and dissolution phenomena, based on the Diffuse Domain method (DDM), which is incorporated into the MsFV approximation of pore-scale states. We apply the proposed hybrid scheme to a reactive flow and transport problem in porous media subject to heterogeneous reactions and the corresponding precipitation and dissolution phenomena.

  14. A novel cardiac MR chamber volume model for mechanical dyssynchrony assessment

    Science.gov (United States)

    Song, Ting; Fung, Maggie; Stainsby, Jeffrey A.; Hood, Maureen N.; Ho, Vincent B.

    2009-02-01

    A novel cardiac chamber volume model is proposed for the assessment of left ventricular mechanical dyssynchrony. The tool is potentially useful for assessment of regional cardiac function and identification of mechanical dyssynchrony on MRI. Dyssynchrony results typically from a contraction delay between one or more individual left ventricular segments, which in turn leads to inefficient ventricular function and ultimately heart failure. Cardiac resynchronization therapy has emerged as an electrical treatment of choice for heart failure patients with dyssynchrony. Prior MRI techniques have relied on assessments of actual cardiac wall changes either using standard cine MR images or specialized pulse sequences. In this abstract, we detail a semi-automated method that evaluates dyssynchrony based on segmental volumetric analysis of the left ventricular (LV) chamber as illustrated on standard cine MR images. Twelve sectors each were chosen for the basal and mid-ventricular slices and 8 sectors were chosen for apical slices for a total of 32 sectors. For each slice (i.e. basal, mid and apical), a systolic dyssynchrony index (SDI) was measured. SDI, a parameter used for 3D echocardiographic analysis of dyssynchrony, was defined as the corrected standard deviation of the time at which minimal volume is reached in each sector. The SDI measurement of a healthy volunteer was 3.54%. In a patient with acute myocardial infarction, the SDI measurements 10.98%, 16.57% and 1.41% for basal, mid-ventricular and apical LV slices, respectively. Based on published 3D echocardiogram reference threshold values, the patient's SDI corresponds to moderate basal dysfunction, severe mid-ventricular dysfunction, and normal apical LV function, which were confirmed on echocardiography. The LV chamber segmental volume analysis model and SDI is feasible using standard cine MR data and may provide more reliable assessment of patients with dyssynchrony especially if the LV myocardium is thin or if

  15. Hydrodynamic modelling of free water-surface constructed storm water wetlands using a finite volume technique.

    Science.gov (United States)

    Zounemat-Kermani, Mohammad; Scholz, Miklas; Tondar, Mohammad-Mahdi

    2015-01-01

    One of the key factors in designing free water-surface constructed wetlands (FWS CW) is the hydraulic efficiency (λ), which depends primarily on the retention time of the polluted storm water. Increasing the hydraulic retention time (HRT) at various flow levels will increase λ of the overall constructed wetland (CW). The effects of characteristic geometric features that increase HRT were explored through the use of a two-dimensional depth-average hydrodynamic model. This numerical model was developed to solve the equations of continuity and motions on an unstructured triangular mesh using the Galerkin finite volume formulation and equations of the k-ε turbulence model. Eighty-nine diverse forms of artificial FWS CW with 11 different aspect ratios were numerically simulated and subsequently analysed for four scenarios: rectangular CW, modified rectangular CW with rounded edges, different inlet/outlet configurations of CW, and surface and submerged obstructions in front of the inlet part of the CW. Results from the simulations showed that increasing the aspect ratio has a direct influence on the enhancement of λ in all cases. However, the aspect ratio should be at least 9 in order to achieve an appropriate rate for λ in rectangular CW. Modified rounded rectangular CW improved λ by up to 23%, which allowed for the selection of a reduced aspect ratio. Simulation results showed that CW with low aspect ratios benefited from obstructions and optimized inlet/outlet configurations in terms of improved HRT.

  16. Towards a sharp-interface volume-of-fluid methodology for modeling evaporation

    Science.gov (United States)

    Pathak, Ashish; Raessi, Mehdi

    2017-11-01

    In modeling evaporation, the diffuse-interface (one-domain) formulation yields inaccurate results. Recent efforts approaching the problem via a sharp-interface (two-domain) formulation have shown significant improvements. The reasons behind their better performance are discussed in the present work. All available sharp-interface methods, however, exclusively employ the level-set. In the present work, we develop a sharp-interface evaporation model in a volume-of-fluid (VOF) framework in order to leverage its mass-conserving property as well as its ability to handle large topographical changes. We start with a critical review of the assumptions underlying the mathematical equations governing evaporation. For example, it is shown that the assumption of incompressibility can only be applied in special circumstances. The famous D2 law used for benchmarking is valid exclusively to steady-state test problems. Transient is present over significant lifetime of a micron-size droplet. Therefore, a 1D spherical fully transient model is developed to provide a benchmark transient solution. Finally, a 3D Cartesian Navier-Stokes evaporation solver is developed. Some preliminary validation test-cases are presented for static and moving drop evaporation. This material is based upon work supported by the Department of Energy, Office of Energy Efficiency and Renewable Energy and the Department of Defense, Tank and Automotive Research, Development, and Engineering Center, under Award Number DEEE0007292.

  17. Free volume model for the unexpected effect of C2-methylation on the properties of imidazolium ionic liquids.

    Science.gov (United States)

    Chen, Zheng Jian; Lee, Jong-Min

    2014-03-13

    For 1-alkyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imides and their cationic C2-methylated isomers, that is, [C(n)MIm]NTf2 and [C(n-1)DMIm]NTf2 (n = 3-8), the latter always has much higher viscosities (∼1.66 times at 25 °C) than the former. This finding is unexpected and contrary to the loss of the predominant hydrogen bonding between the cation and anion, caused by the C2-methylation in the imidazolium ionic liquids. In the present study, we propose a free volume model to explain this mysterious phenomenon. For the isomeric pairs, [C(n-1)DMIm]NTf2 was found to possess less unoccupied (free) volume than [C(n)MIm]NTf2 by ∼4.5 mL mol(-1) determined by both Fürth's surface tension and molar volume methods, and the free volume difference can be quantitatively correlated with the C2-methylation effect on viscosity. Generally, the less free volume in [C(n-1)DMIm]NTf2 relative to [C(n)MIm]NTf2 reduces the number of the hole carriers for molecular transport with a resulting increase in viscosity. Besides, the free volume model can also be applied to account for the C2-methylation effect on other properties, such as conductivity, surface tension, density, and refractive index.

  18. Numerical modelling in building thermo-aeraulics: from CFD modelling to an hybrid finite volume / zonal approach; Modelisation numerique de la thermoaeraulique du batiment: des modeles CFD a une approche hybride volumes finis / zonale

    Energy Technology Data Exchange (ETDEWEB)

    Bellivier, A.

    2004-05-15

    For 3D modelling of thermo-aeraulics in building using field codes, it is necessary to reduce the computing time in order to model increasingly larger volumes. The solution suggested in this study is to couple two modelling: a zonal approach and a CFD approach. The first part of the work that was carried out is the setting of a simplified CFD modelling. We propose rules for use of coarse grids, a constant effective viscosity law and adapted coefficients for heat exchange in the framework of building thermo-aeraulics. The second part of this work concerns the creation of fluid Macro-Elements and their coupling with a calculation of CFD finite volume type. Depending on the boundary conditions of the problem, a local description of the driving flow is proposed via the installation and use of semi-empirical evolution laws. The Macro-Elements is then inserted in CFD computation: the values of velocity calculated by the evolution laws are imposed on the CFD cells corresponding to the Macro-Element. We use these two approaches on five cases representative of thermo-aeraulics in buildings. The results are compared with experimental data and with traditional RANS simulations. We highlight the significant gain of time that our approach allows while preserving a good quality of numerical results. (author)

  19. Final safety analysis report for the Galileo Mission: Volume 2: Book 1, Accident model document

    Energy Technology Data Exchange (ETDEWEB)

    1988-12-15

    The Accident Model Document (AMD) is the second volume of the three volume Final Safety Analysis Report (FSAR) for the Galileo outer planetary space science mission. This mission employs Radioisotope Thermoelectric Generators (RTGs) as the prime electrical power sources for the spacecraft. Galileo will be launched into Earth orbit using the Space Shuttle and will use the Inertial Upper Stage (IUS) booster to place the spacecraft into an Earth escape trajectory. The RTG's employ silicon-germanium thermoelectric couples to produce electricity from the heat energy that results from the decay of the radioisotope fuel, Plutonium-238, used in the RTG heat source. The heat source configuration used in the RTG's is termed General Purpose Heat Source (GPHS), and the RTG's are designated GPHS-RTGs. The use of radioactive material in these missions necessitates evaluations of the radiological risks that may be encountered by launch complex personnel as well as by the Earth's general population resulting from postulated malfunctions or failures occurring in the mission operations. The FSAR presents the results of a rigorous safety assessment, including substantial analyses and testing, of the launch and deployment of the RTGs for the Galileo mission. This AMD is a summary of the potential accident and failure sequences which might result in fuel release, the analysis and testing methods employed, and the predicted source terms. Each source term consists of a quantity of fuel released, the location of release and the physical characteristics of the fuel released. Each source term has an associated probability of occurrence. 27 figs., 11 tabs.

  20. Accuracy of near-patient vs. inbuilt spirometry for monitoring tidal volumes in an in-vitro paediatric lung model.

    Science.gov (United States)

    Morgenroth, S; Thomas, J; Cannizzaro, V; Weiss, M; Schmidt, A R

    2018-03-01

    Spirometric monitoring provides precise measurement and delivery of tidal volumes within a narrow range, which is essential for lung-protective strategies that aim to reduce morbidity and mortality in mechanically-ventilated patients. Conventional anaesthesia ventilators include inbuilt spirometry to monitor inspiratory and expiratory tidal volumes. The GE Aisys CS 2 anaesthesia ventilator allows additional near-patient spirometry via a sensor interposed between the proximal end of the tracheal tube and the respiratory tubing. Near-patient and inbuilt spirometry of two different GE Aisys CS 2 anaesthesia ventilators were compared in an in-vitro study. Assessments were made of accuracy and variability in inspiratory and expiratory tidal volume measurements during ventilation of six simulated paediatric lung models using the ASL 5000 test lung. A total of 9240 breaths were recorded and analysed. Differences between inspiratory tidal volumes measured with near-patient and inbuilt spirometry were most significant in the newborn setting (p tidal volume measurements with near-patient spirometry were consistently more accurate than with inbuilt spirometry for all lung models (p tidal volumes decreased with increasing tidal volumes, and was smaller with near-patient than with inbuilt spirometry. The variability in measured tidal volumes was higher during expiration, especially with inbuilt spirometry. In conclusion, the present in-vitro study shows that measurements with near-patient spirometry are more accurate and less variable than with inbuilt spirometry. Differences between measurement methods were most significant in the smallest patients. We therefore recommend near-patient spirometry, especially for neonatal and paediatric patients. © 2018 The Association of Anaesthetists of Great Britain and Ireland.

  1. Understanding why the volume of suboxic waters does not increase over centuries of global warming in an Earth System Model

    OpenAIRE

    A. Gnanadesikan; J. P. Dunne; J. John

    2012-01-01

    Global warming is expected to reduce oxygen solubility and vertical exchange in the ocean, changes which would be expected to result in an increase in the volume of hypoxic waters. A simulation made with a full Earth System model with dynamical atmosphere, ocean, sea ice and biogeochemical cycling (the Geophysical Fluid Dynamics Laboratory's Earth System Model 2.1) shows that this holds true if the condition for hypoxia is set relatively high. However, the volume of the most hypoxic (i.e., su...

  2. Graphite furnace atomic absorption spectrophotometry--a novel method to quantify blood volume in experimental models of intracerebral hemorrhage.

    Science.gov (United States)

    Kashefiolasl, Sepide; Foerch, Christian; Pfeilschifter, Waltraud

    2013-02-15

    Intracerebral hemorrhage (ICH) accounts for 10% of all strokes and has a significantly higher mortality than cerebral ischemia. For decades, ICH has been neglected by experimental stroke researchers. Recently, however, clinical trials on acute blood pressure lowering or hyperacute supplementation of coagulation factors in ICH have spurred an interest to also design and improve translational animal models of spontaneous and anticoagulant-associated ICH. Hematoma volume is a substantial outcome parameter of most experimental ICH studies. We present graphite furnace atomic absorption spectrophotometric analysis (AAS) as a suitable method to precisely quantify hematoma volumes in rodent models of ICH. Copyright © 2012 Elsevier B.V. All rights reserved.

  3. Optimal definition of biological tumor volume using positron emission tomography in an animal model.

    Science.gov (United States)

    Wu, Ingrid; Wang, Hao; Huso, David; Wahl, Richard L

    2015-12-01

    -value-threshold tumor contouring using (18)F-FDG-PET is able to accurately delineate the viable portion of a tumor. 30 and 35 % of Cmax, 30 and 35 % of Cpeak, and 6 × Cliver + 2 × SD are three appropriate threshold values to delineate viable tumor volume in our animal model. The commonly used threshold value of 50 % of Cmax or Cpeak failed to detect one third of the viable tumor volume in our model.

  4. A stable algorithm for calculating phase equilibria with capillarity at specified moles, volume and temperature using a dynamic model

    KAUST Repository

    Kou, Jisheng

    2017-09-30

    Capillary pressure can significantly affect the phase properties and flow of liquid-gas fluids in porous media, and thus, the phase equilibrium calculation incorporating capillary pressure is crucial to simulate such problems accurately. Recently, the phase equilibrium calculation at specified moles, volume and temperature (NVT-flash) becomes an attractive issue. In this paper, capillarity is incorporated into the phase equilibrium calculation at specified moles, volume and temperature. A dynamical model for such problem is developed for the first time by using the laws of thermodynamics and Onsager\\'s reciprocal principle. This model consists of the evolutionary equations for moles and volume, and it can characterize the evolutionary process from a non-equilibrium state to an equilibrium state in the presence of capillarity effect at specified moles, volume and temperature. The phase equilibrium equations are naturally derived. To simulate the proposed dynamical model efficiently, we adopt the convex-concave splitting of the total Helmholtz energy, and propose a thermodynamically stable numerical algorithm, which is proved to preserve the second law of thermodynamics at the discrete level. Using the thermodynamical relations, we derive a phase stability condition with capillarity effect at specified moles, volume and temperature. Moreover, we propose a stable numerical algorithm for the phase stability testing, which can provide the feasible initial conditions. The performance of the proposed methods in predicting phase properties under capillarity effect is demonstrated on various cases of pure substance and mixture systems.

  5. Pengembangan Model Pembelajaran Matematika Volum Benda Putar Berbasis Teknologi Dengan Strategi Konstruktivisme Student Active Learning Berbantuan CD Interaktif Kelas XII

    Directory of Open Access Journals (Sweden)

    M S Rudiyanto

    2010-06-01

    Full Text Available Kemampuan mengkonstruksi pengetahuan merupakan aspek yang penting dalam belajar matematika. Rendahnya kemampuan siswa dalam mengkonstruksi pengetahuan mempengaruhi kualitas belajar siswa yang berdampak pada rendahnya prestasi belajar siswa. Salah satu upaya untuk mengatasi hal tersebut dilakukan dengan pembelajaran yang menekankan keaftifan siswa. Model pembelajaran yang menekankan siswa yang akan dibahas pada makalah ini adalah Model pembelajaran dengan Strategi Konstruktivisme Student Active Learning berbantuan CD interaktif (KSAL. Pengembangan model pembelajaran KSAL mengacu pada model pengembangan Plom (1977 yang terdiri dari Premilinary Investigation, Design, Realization, Test, Evaluation, Revision, and Implementation. Model KSAL memiliki unsure sintakmatik yang tercermin dalam RPP memuat strategi yang merupakan modifikasi model TTW dan model CLD yang terdiri dari bridge, grouping, think, write, reflection, and evaluation. Model ini menempatkan guru sebagai fasilitator. CD interaktif dalam model KSAL ini dirancang agar siwa belajar mandiri. Materi dalam CD terdiri dari materi volum benda putar, lembar kerja siswa, lembar tugas siswa, permainan dan tes akhir dan disusun secara kontruktivisme yakni memungkinkan siswa membangun pengetahuan dalam menemukan konsep volum benda putar. Kata kunci: kontruktivisme, Student Active Learning, volum benda putar.

  6. Assessment of organ volume with different techniques using a living liver model

    Energy Technology Data Exchange (ETDEWEB)

    Luccichenti, Giacomo; Cobelli, Rocco; Pavone, Paolo [Department of Radiology, University of Parma, Via A. Gramsci, 14, 43100 Parma (Italy); Cademartiri, Filippo [Department of Radiology, University of Parma, Via A. Gramsci, 14, 43100 Parma (Italy); Department of Radiology, Erasmus Medical Center, Rotterdam (Netherlands)

    2003-06-01

    The purpose of this study was to compare different techniques for the estimation of liver volume, and to evaluate errors associated with volume estimation techniques based on linear measurements. Fifteen patients with focal liver lesion underwent spiral CTA for preoperative evaluation. The scan protocol was: collimation 3 mm; rotation time 0.75 s; pitch 2; and reconstruction index 1 mm. Reconstructed images were sent to a workstation running on a NT platform equipped with post-processing software allowing 3D reconstructions. Linear measurements and volume estimation through manual segmentation were obtained with preset window and magnification. Volume was calculated from linear measures using different equations. With equations based on linear measurements the right lobe was overestimated (mean=+53%; mean error=14.7%), the second and third segments were underestimated (mean=-47%; mean error=43.3%) and the total volume was underestimated (mean=-86%; mean error=36%). The volume calculated by summing the areas of all the sections and multiplying the result by the increment was not significantly different from the volume estimated using the manual volumetric segmentation technique. Volume estimation obtained through linear measurements is not reliable to appraise the volume of irregular-shaped solids, even assuming the prevalence of a particular morphology. (orig.)

  7. A Cercla-Based Decision Model to Support Remedy Selection for an Uncertain Volume of Contaminants at a DOE Facility

    Energy Technology Data Exchange (ETDEWEB)

    Christine E. Kerschus

    1999-03-31

    The Paducah Gaseous Diffusion Plant (PGDP) operated by the Department of Energy is challenged with selecting the appropriate remediation technology to cleanup contaminants at Waste Area Group (WAG) 6. This research utilizes value-focused thinking and multiattribute preference theory concepts to produce a decision analysis model designed to aid the decision makers in their selection process. The model is based on CERCLA's five primary balancing criteria, tailored specifically to WAG 6 and the contaminants of concern, utilizes expert opinion and the best available engineering, cost, and performance data, and accounts for uncertainty in contaminant volume. The model ranks 23 remediation technologies (trains) in their ability to achieve the CERCLA criteria at various contaminant volumes. A sensitivity analysis is performed to examine the effects of changes in expert opinion and uncertainty in volume. Further analysis reveals how volume uncertainty is expected to affect technology cost, time and ability to meet the CERCLA criteria. The model provides the decision makers with a CERCLA-based decision analysis methodology that is objective, traceable, and robust to support the WAG 6 Feasibility Study. In addition, the model can be adjusted to address other DOE contaminated sites.

  8. A Cercla-Based Decision Model to Support Remedy Selection for an Uncertain Volume of Contaminants at a DOE Facility

    International Nuclear Information System (INIS)

    Christine E. Kerschus

    1999-01-01

    The Paducah Gaseous Diffusion Plant (PGDP) operated by the Department of Energy is challenged with selecting the appropriate remediation technology to cleanup contaminants at Waste Area Group (WAG) 6. This research utilizes value-focused thinking and multiattribute preference theory concepts to produce a decision analysis model designed to aid the decision makers in their selection process. The model is based on CERCLA's five primary balancing criteria, tailored specifically to WAG 6 and the contaminants of concern, utilizes expert opinion and the best available engineering, cost, and performance data, and accounts for uncertainty in contaminant volume. The model ranks 23 remediation technologies (trains) in their ability to achieve the CERCLA criteria at various contaminant volumes. A sensitivity analysis is performed to examine the effects of changes in expert opinion and uncertainty in volume. Further analysis reveals how volume uncertainty is expected to affect technology cost, time and ability to meet the CERCLA criteria. The model provides the decision makers with a CERCLA-based decision analysis methodology that is objective, traceable, and robust to support the WAG 6 Feasibility Study. In addition, the model can be adjusted to address other DOE contaminated sites

  9. Voxel tree modeling for estimating leaf area density and woody material volume using 3-D LIDAR data

    Directory of Open Access Journals (Sweden)

    F. Hosoi

    2013-10-01

    Full Text Available In this work, the main focus is on voxel tree modeling using 3-D lidar data for accurate leaf area density (LAD and woody material volume estimation. For more accurate LAD estimation, the voxel model was constructed by combining airborne and portable ground-based lidar data. The profiles obtained by the two types of lidar complemented each other, thus eliminating blind regions and yielding more accurate LAD profiles than could be obtained by using each type of lidar alone. Parts of the LAD profiles that were underestimated even when data from both lidars were combined were interpolated by using a Gaussian function, yielding improved results. A laser beam coverage index, Ω, incorporating the lidar's laser beam settings and a laser beam attenuation factor, was proposed. This index showed general applicability to explain the LAD estimation error for LAD measurements using different types of lidars. In addition, we proposed a method for accurate woody material volume estimation based on a 3-D voxel-based solid modeling of the tree from portable scanning lidar data. The solid model was composed of consecutive voxels that filled the outer surface and the interior of the stem and large branches. By using the model, the woody material volume of not only the whole target tree but also of any part of the target tree can be directly calculated easily and accurately by counting the number of corresponding voxels and multiplying the result by the per-voxel volume.

  10. A Novel Approach to Predict 24-Hour Energy Expenditure Based on Hematologic Volumes: Development and Validation of Models Comparable to Mifflin-St Jeor and Body Composition Models.

    Science.gov (United States)

    Chang, Douglas C; Piaggi, Paolo; Krakoff, Jonathan

    2017-08-01

    Accurate prediction of 24-hour energy expenditure (24EE) relies on knowing body composition, in particular fat-free mass (FFM), the largest determinant of 24EE. FFM is closely correlated with hematologic volumes: blood volume (BV), red cell mass (RCM), and plasma volume (PV). However, it is unknown whether predicted hematologic volumes, based on easily collected variables, can improve 24EE prediction. The aim was to develop and validate equations to predict 24EE based on predicted BV, RCM, and PV and to compare the accuracy and agreement with models developed from FFM and with the Mifflin-St Jeor equation, which is recommended for clinical use by the Academy of Nutrition and Dietetics. Participants had body composition measured by underwater weighing and 24EE by respiratory chamber. BV, RCM, and PV were calculated from five published equations. Native American and white men and women were studied (n=351). Participants were healthy adults aged 18 to 49 years from the Phoenix, AZ, metropolitan area. Accuracy to within ±10% of measured 24EE and agreement by Bland-Altman analysis. Regression models to predict 24EE from hematologic and body composition variables were developed in half the dataset and validated in the other half. Hematologic volumes were all strongly correlated with FFM in both men and women (r≥0.94). Whereas the accuracy of FFM alone was 69%, four hematologic volumes were individually more accurate (75% to 78%) in predicting 24EE. Equations based on hematologic volumes plus demographics had mean prediction errors comparable to those based on body composition plus demographics; although the Mifflin-St Jeor had modestly better mean prediction error, body composition, hematologic, and Mifflin-St Jeor models all had similar accuracy (approximately 80%). Prediction equations based on hematologic volumes were developed, validated, and found to be comparable to Mifflin-St Jeor and body composition models in this population of healthy adults. Published by

  11. Probabilistic risk assessment of the Space Shuttle. Phase 3: A study of the potential of losing the vehicle during nominal operation. Volume 4: System models and data analysis

    Science.gov (United States)

    Fragola, Joseph R.; Maggio, Gaspare; Frank, Michael V.; Gerez, Luis; Mcfadden, Richard H.; Collins, Erin P.; Ballesio, Jorge; Appignani, Peter L.; Karns, James J.

    1995-01-01

    In this volume, volume 4 (of five volumes), the discussion is focussed on the system models and related data references and has the following subsections: space shuttle main engine, integrated solid rocket booster, orbiter auxiliary power units/hydraulics, and electrical power system.

  12. Theoretical modeling and design of photonic structures in zeolite nanocomposites for gas sensing. Part II: volume gratings.

    Science.gov (United States)

    Cody, D; Naydenova, I

    2018-01-01

    The suitability of holographic structures fabricated in zeolite nanoparticle-polymer composite materials for gas sensing applications has been investigated. Theoretical modeling of the sensor response (i.e., change in hologram readout due to a change in refractive index modulation or thickness as a result of gas adsorption) of different sensor designs was carried out using the Raman-Nath theory and Kogelnik's coupled wave theory. The influence of a range of parameters on the sensitivity of holographically recorded surface and volume photonic structures has been studied, namely, hologram geometry, hologram thickness and spatial frequency, reconstruction wavelength, and zeolite nanoparticle refractive index. From this, the optimum fabrication conditions for both surface and volume holographic gas sensor designs have been identified. Here in Part II, results from modeling of the influence of design on the sensor response of holographically recorded volume grating structures for gas sensing applications are reported.

  13. BOX MEDIA MODEL THROUGH THE USE OF CONTEXTUAL UNDERSTANDING TO IMPROVE STUDENT LEARNING CONCEPTS IN VOLUME BEAM

    Directory of Open Access Journals (Sweden)

    Dede Rohaeni

    2016-05-01

    Full Text Available Abstract. This research is motivated Cilengkrang Elementary School fifth grade students in the learning of the beam volume is still experiencing difficulties. This happens because the learning process that takes place is conventional. Learning by applying a contextual model chosen researchers by reason students will know if the learning is associated with the real world of students. The method used in this research is a classroom action research methods to the design of the research procedure refers to the spiral model Kemmis and MC. Tujuanpenelitianini is to obtain an overview of the planning, implementation and improvement of students' understanding of the results of the application of the concept model of contextual learning in the classroom beam volume V Elementary School Cilengkrang. The method used in this research is a classroom action research methods to the design of the research procedure refers to the spiral model Kemmis and MC. Taggart. Based on the implementation of the actions performed by three cycles, as a whole has shown an increase from the initial data, both process and outcomes of learning. So that the application of contextual models can enhance students' understanding of class V SDN Cilengkrang Northern District of Sumedang Sumedang district of the concept of the beam volume.   Keywords: Contextual Model, Mathematics, Mathematics Learning Objectives     Abstrak. Penelitian ini dilatarbelakangi siswa kelas V SDN Cilengkrang dalam pembelajaran volume balok masih mengalami kesulitan. Ini terjadi karena proses pembelajaran yang berlangsung bersifat konvensional. Pembelajaran dengan menerapkan model kontekstual dipilih peneliti dengan alasan siswa akan paham jika pembelajaran dikaitkan dengan dunia nyata siswa. Metode penelitian yang digunakan dalam penelitian ini adalah metode penelitian tindakan kelas dengan rancangan prosedur penelitiannya mengacu pada model spiral Kemmis dan MC. Tujuanpenelitianini yaitu untuk memperoleh

  14. Volume Oscillations Delivered to a Lung Model Using 4 Different Bubble CPAP Systems.

    Science.gov (United States)

    Poli, Jonathan A; Richardson, C Peter; DiBlasi, Robert M

    2015-03-01

    High-frequency pressure oscillations created by gas bubbling through an underwater seal during bubble CPAP may enhance ventilation and aid in lung recruitment in premature infants. We hypothesized that there are no differences in the magnitude of oscillations in lung volume (ΔV) in a preterm neonatal lung model when different bubble CPAP systems are used. An anatomically realistic replica of an infant nasal airway model was attached to a Silastic test lung sealed within a calibrated plethysmograph. Nasal prongs were affixed to the simulated neonate and supported using bubble CPAP systems set at 6 cm H2O. ΔV was calculated using pressure measurements obtained from the plethysmograph. The Fisher & Paykel Healthcare bubble CPAP system provided greater ΔV than any of the other devices at all of the respective bias flows (P CPAP systems. The magnitude of ΔV increased at bias flows of > 4 L/min in the Fisher & Paykel Healthcare, Airways Development, and homemade systems, but appeared to decrease as bias flow increased with the Babi.Plus system. The major finding of this study is that bubble CPAP can provide measureable ventilation effects in an infant lung model. We speculate that the differences noted in ΔV between the different devices are a combination of the circuit/nasal prong configuration, bubbler configuration, and frequency of oscillations. Additional testing is needed in spontaneously breathing infants to determine whether a physiologic benefit exists when using the different bubble CPAP systems. Copyright © 2015 by Daedalus Enterprises.

  15. Impact of the volume of gaseous phase in closed reactors on ANC results and modelling

    Science.gov (United States)

    Drapeau, Clémentine; Delolme, Cécile; Lassabatere, Laurent; Blanc, Denise

    2016-04-01

    The understanding of the geochemical behavior of polluted solid materials is often challenging and requires huge expenses of time and money. Nevertheless, given the increasing amounts of polluted solid materials and related risks for the environment, it is more and more crucial to understand the leaching of majors and trace metals elements from these matrices. In the designs of methods to quantify pollutant solubilization, the combination of experimental procedures with modeling approaches has recently gained attention. Among usual methods, some rely on the association of ANC and geochemical modeling. ANC experiments - Acid Neutralization Capacity - consists in adding known quantities of acid or base to a mixture of water and contaminated solid materials at a given liquid / solid ratio in closed reactors. Reactors are agitated for 48h and then pH, conductivity, redox potential, carbon, majors and heavy metal solubilized are quantified. However, in most cases, the amounts of matrix and water do not reach the total volume of reactors, leaving some space for air (gaseous phase). Despite this fact, no clear indication is given in standard procedures about the effect of this gaseous phase. Even worse, the gaseous phase is never accounted for when exploiting or modeling ANC data. The gaseous phase may exchange CO2 with the solution, which may, in turn, impact both pH and element release. This study lies within the most general framework for the use of geochemical modeling for the prediction of ANC results for the case of pure phases to real phase assemblages. In this study, we focus on the effect of the gaseous phase on ANC experiments on different mineral phases through geochemical modeling. To do so, we use PHREEQC code to model the evolution of pH and element release (including majors and heavy metals) when several matrices are put in contact with acid or base. We model the following scenarios for the gaseous phase: no gas, contact with the atmosphere (open system

  16. Deciding between compensated volume balance and real time transient models for pipeline leak detection system

    Energy Technology Data Exchange (ETDEWEB)

    Baptista, Renan Martins [PETROBRAS, Rio de Janeiro, RJ (Brazil). Centro de Pesquisas. Div. de Explotacao]. E-mail: renan@cenpes.petrobras.com.br

    2000-07-01

    This paper describes a technical procedure to assess a software based leak detection system (LDS), by deciding between a simpler low cost, less effective product, having a fast installation and tuning, and a complex one with high cost and efficiency, which however takes a long time to be properly installed. This is a common decision among the pipeline operating companies, considering that the majority of the lines are short, with single phase liquid flow (which may include batches), basic communication system and instrumentation. Service companies offer realistic solutions for liquid flow, but usually designed to big pipeline networks, flowing multiple batches and allowing multiple fluid entrances and deliveries. Those solutions are sometimes impractical to short pipelines, due to its high cost, as well as long tuning procedures, complex instrumentation, communication and computer requirements. It is intended to approach here the best solution according to its cost. In a practical sense, it means to differentiate the various LDS techniques. Those techniques are available in a considerable number, and they are still spreading, according to the different scenarios. However, two most known and worldwide implemented techniques hold the majority of the market: the Compensated Volume Balance (CVB), which is less accurate, reliable and robust, but cheaper, simpler and faster to install, and the Real Time Transient Model (RTTM), which is very reliable, accurate and robust, but expensive and complex. This work will describe a way to define whether one can use or not a CVB in a pipeline. (author)

  17. Monitoring the trajectory of urban nighttime light hotspots using a Gaussian volume model

    Science.gov (United States)

    Zheng, Qiming; Jiang, Ruowei; Wang, Ke; Huang, Lingyan; Ye, Ziran; Gan, Muye; Ji, Biyong

    2018-03-01

    Urban nighttime light hotspot is an ideal representation of the spatial heterogeneity of human activities within a city, which is sensitive to regional urban expansion pattern. However, most of previous studies related to nighttime light imageries focused on extracting urban extent, leaving the spatial variation of radiance intensity insufficiently explored. With the help of global radiance calibrated DMSP-OLS datasets (NTLgrc), we proposed an innovative framework to explore the spatio-temporal trajectory of polycentric urban nighttime light hotspots. Firstly, NTLgrc was inter-annually calibrated to improve the consistency. Secondly, multi-resolution segmentation and region-growing SVM classification were employed to remove blooming effect and to extract potential clusters. At last, the urban hotspots were identified by a Gaussian volume model, and the resulting parameters were used to quantitatively depict hotspot features (i.e., intensity, morphology and centroid dynamics). The result shows that our framework successfully captures hotspots in polycentric urban area, whose Ra2 are over 0.9. Meanwhile, the spatio-temporal dynamics of the hotspot features intuitively reveal the impact of the regional urban growth pattern and planning strategies on human activities. Compared to previous studies, our framework is more robust and offers an effective way to describe hotspot pattern. Also, it provides a more comprehensive and spatial-explicit understanding regarding the interaction between urbanization pattern and human activities. Our findings are expected to be beneficial to governors in term of sustainable urban planning and decision making.

  18. A model for steady-state large-volume plasma generation

    International Nuclear Information System (INIS)

    Uhm, H.S.; Miller, J.D.; Schneider, R.F.

    1991-01-01

    In this paper, a simple, new scheme to generate a uniform, steady-state, large-volume plasma is presented. The weakly magnetized plasma is created by direct ionization of the background gas by low-energy electrons generated from thermionic filaments. An annular arrangement of the filaments ensures a uniform plasma density in the radial direction as predicted by theory. Experiments have been performed to characterize the plasma generated in such a configuration. In order to explain the experimental observation, we develop a bulk plasma theory based on plasma transport via cross-field diffusion. As assumed in the theoretical model, the experimental measurements indicate a uniform plasma density along the axis. Both the theory and experiment indicate that the plasma density is a function of the square of the external magnetic field. The theory also predicts the plasma density to be proportional to the neutral density to the two-thirds power in agreement with the experimental data. We also observe the experimental data to agree remarkably well with theoretical prediction for a broad range of system parameters

  19. A comprehensive Guyton model analysis of physiologic responses to preadapting the blood volume as a countermeasure to fluid shifts

    Science.gov (United States)

    Simanonok, K. E.; Srinivasan, R. S.; Myrick, E. E.; Blomkalns, A. L.; Charles, J. B.

    1994-01-01

    The Guyton model of fluid, electrolyte, and circulatory regulation is an extensive mathematical model capable of simulating a variety of experimental conditions. It has been modified for use at NASA to simulate head-down tilt, a frequently used analog of weightlessness. Weightlessness causes a headward shift of body fluids that is believed to expand central blood volume, triggering a series of physiologic responses resulting in large losses of body fluids. We used the modified Guyton model to test the hypothesis that preadaptation of the blood volume before weightless exposure could counteract the central volume expansion caused by fluid shifts, and thereby attenuate the circulatory and renal responses that result in body fluid losses. Simulation results show that circulatory preadaptation, by a procedure resembling blood donation immediately before head-down bedrest, is effective in damping the physiologic responses to fluid shifts and reducing body fluid losses. After 10 hours of head-down tilt, preadaptation also produces higher blood volume, extracellular volume, and total body water for 20 to 30 days of bedrest, compared with non-preadapted control. These results indicate that circulatory preadaptation before current Space Shuttle missions may be beneficial for the maintenance of reentry and postflight orthostatic tolerance in astronauts. This paper presents a comprehensive examination of the simulation results pertaining to changes in relevant physiologic variables produced by blood volume reduction before a prolonged head-down tilt. The objectives were to study and develop the countermeasure theoretically, to aid in planning experimental studies of the countermeasure, and to identify potentially disadvantageous physiologic responses that may be caused by the countermeasure.

  20. Modeling volume effects of experimental brachytherapy in the rat rectum: uncovering the limitations of a radiobiologic concept

    International Nuclear Information System (INIS)

    Johannessen, Hans-Olaf; Dale, Einar; Hellebust, Taran P.; Olsen, Dag R.; Nesland, Jahn M.; Giercksky, Karl-Erik

    2002-01-01

    Purpose: To analyze the significance of volume effects in experimental brachytherapy, based on modeling normal tissue complication probability. Methods and Materials: Experimental brachytherapy in the rat rectum was based on an eight-step 2.5-mm step size source configuration for 192 Ir, afterloaded into an unshielded polystyrene applicator. Volume effects were studied using a half-circumferential lead-shielded applicator and a shorter (two-step) source configuration. The main end point was rectal stenosis. Results: Rectal stenosis was always caused by a radiation ulcer. With the shielded configuration, single-dose ED 50 (50% incidence of rectal stenosis) increased from 23 Gy to 36.5 Gy. Single-dose ED 50 for the short configuration was 77.9 Gy. The data showed a reasonable fit to a three-parameter version of the biophysical model described by Jackson et al. (1995). This model assumes that organs consist of a large number of radiobiologically independent subunits and that radiation causes a complication if the fraction of the organ damaged is greater than its functional reserve. The fraction of the organ damaged is calculated summing over fractions of the organ damaged at each dose level. The calculated mean functional reserve (ν 50 ) of the rat rectum, assuming a cumulative functional reserve distribution in the group of experimental rats, was 0.53. Conclusions: The volume effect observed within small brachytherapy volumes agreed well with clinical experience of large tolerance doses in contact X-ray therapy. However, the ν 50 value was comparable to the high functional reserve value reported for liver. Experimental volume effects probably reflect repair processes originating in the areas adjacent to small radiation fields of brachytherapy more than the radiobiologic characteristics of the cells in the irradiated volume

  1. Volume-weighted particle-tracking method for solute-transport modeling; Implementation in MODFLOW–GWT

    Science.gov (United States)

    Winston, Richard B.; Konikow, Leonard F.; Hornberger, George Z.

    2018-02-16

    In the traditional method of characteristics for groundwater solute-transport models, advective transport is represented by moving particles that track concentration. This approach can lead to global mass-balance problems because in models of aquifers having complex boundary conditions and heterogeneous properties, particles can originate in cells having different pore volumes and (or) be introduced (or removed) at cells representing fluid sources (or sinks) of varying strengths. Use of volume-weighted particles means that each particle tracks solute mass. In source or sink cells, the changes in particle weights will match the volume of water added or removed through external fluxes. This enables the new method to conserve mass in source or sink cells as well as globally. This approach also leads to potential efficiencies by allowing the number of particles per cell to vary spatially—using more particles where concentration gradients are high and fewer where gradients are low. The approach also eliminates the need for the model user to have to distinguish between “weak” and “strong” fluid source (or sink) cells. The new model determines whether solute mass added by fluid sources in a cell should be represented by (1) new particles having weights representing appropriate fractions of the volume of water added by the source, or (2) distributing the solute mass added over all particles already in the source cell. The first option is more appropriate for the condition of a strong source; the latter option is more appropriate for a weak source. At sinks, decisions whether or not to remove a particle are replaced by a reduction in particle weight in proportion to the volume of water removed. A number of test cases demonstrate that the new method works well and conserves mass. The method is incorporated into a new version of the U.S. Geological Survey’s MODFLOW–GWT solute-transport model.

  2. A dynamic model of the piezoelectric traveling wave rotary ultrasonic motor stator with the finite volume method.

    Science.gov (United States)

    Renteria Marquez, I A; Bolborici, V

    2017-05-01

    This manuscript presents a method to model in detail the piezoelectric traveling wave rotary ultrasonic motor (PTRUSM) stator response under the action of DC and AC voltages. The stator is modeled with a discrete two dimensional system of equations using the finite volume method (FVM). In order to obtain accurate results, a model of the stator bridge is included into the stator model. The model of the stator under the action of DC voltage is presented first, and the results of the model are compared versus a similar model using the commercial finite element software COMSOL Multiphysics. One can observe that there is a difference of less than 5% between the displacements of the stator using the proposed model and the one with COMSOL Multiphysics. After that, the model of the stator under the action of AC voltages is presented. The time domain analysis shows the generation of the traveling wave in the stator surface. One can use this model to accurately calculate the stator surface velocities, elliptical motion of the stator surface and the amplitude and shape of the stator traveling wave. A system of equations discretized with the finite volume method can easily be transformed into electrical circuits, because of that, FVM may be a better choice to develop a model-based control strategy for the PTRUSM. Copyright © 2017 Elsevier B.V. All rights reserved.

  3. Ovarian volume throughout life

    DEFF Research Database (Denmark)

    Kelsey, Thomas W; Dodwell, Sarah K; Wilkinson, A Graham

    2013-01-01

    cancer. To date there is no normative model of ovarian volume throughout life. By searching the published literature for ovarian volume in healthy females, and using our own data from multiple sources (combined n=59,994) we have generated and robustly validated the first model of ovarian volume from...... to about 2.8 mL (95% CI 2.7-2.9 mL) at the menopause and smaller volumes thereafter. Our model allows us to generate normal values and ranges for ovarian volume throughout life. This is the first validated normative model of ovarian volume from conception to old age; it will be of use in the diagnosis...

  4. Comparison of quantitative estimation of intracerebral hemorrhage and infarct volumes after thromboembolism in an embolic stroke model

    DEFF Research Database (Denmark)

    Eriksen, Nina; Rasmussen, Rune Skovgaard; Overgaard, Karsten

    2014-01-01

    BACKGROUND: Strokes have both ischemic and hemorrhagic components, but most studies of experimental stroke only address the ischemic component. This is likely because investigations of hemorrhagic transformation are hindered by the lack of methods based on unbiased principles for volume estimation....... AIMS: We evaluated different methods for estimating the volume of infarcts, hemorrhages, after embolic middle cerebral artery occlusion with or without thrombolysis. METHODS: An experimental thromboembolytic rat model was used in this study. The rats underwent surgery and were placed in two groups...... of measuring both the ischemic and the hemorrhagic components of stroke, two parameters that may be differentially regulated when therapeutic regimens are tested....

  5. Postmortem interval estimation using the animal model of postmortem gas volume changes.

    Science.gov (United States)

    Iwamoto, Chika; Ohuchida, Kenoki; Okumura, Miki; Usumoto, Yosuke; Kishimoto, Junji; Murata, Masaharu; Ikeda, Noriaki; Hashizume, Makoto

    2017-12-20

    It is important to estimate the postmortem interval in forensic autopsy. Many methods to estimate the postmortem interval have been reported, and are typically associated with internal examination. However, there are issues such as rejection of autopsy by the family and a lack of forensic doctor in internal examination. Therefore, it is necessary to develop new methods, such as autopsy imaging, that can substitute for internal examination. Here, we first evaluated whether gas volume in the body increased with postmortem interval. Time-dependent X-ray CT imaging of euthanized Crl:CD (SD) rats (n = 3) was performed immediately after euthanasia and at seven subsequent time points up to 168 h (7 days) at 24-hour intervals. The data revealed that gas volume in the body increased in a time-dependent manner. Next, we reconstructed 3D images of isolated gas and calculated the gas volume using Amira software. In all cases, the volume of both portal venous gas and intestinal gas increased in a time-dependent manner. The volume of portal venous gas increased exponentially, while the volume of intestinal gas increased in a linearly with time. These data might be suggested that the postmortem gas volume change is one of indicators for estimating the postmortem interval. In addition, it would be possible to estimate more accurate postmortem interval by combining not only gas volume changes at the above two sites but also gas volume changes of the other sites such as heart cavities, kidney parenchyma, or abdominal aorta. Copyright © 2017 Elsevier B.V. All rights reserved.

  6. Developments in modelling of thermohydro-geomechanical behaviour of Boom clay and clay-based buffer materials (volume 2)

    International Nuclear Information System (INIS)

    Baldi, G.; Hueckel, T.; Peano, A.; Pellegrini, R.

    1991-01-01

    This study is composed of two parts: The first part (Volume 1) lays the foundations of a comprehensive theoretical treatment of the interaction between water and soil skeleton during thermal dilatation. The second part (volume 2) is devoted to the development and the application of advance constitutive modelling of mechanical behaviour of clays taking into account the extensive tests of Boom clay reported in the first volume. The development concentrated on the improvement of prediction of the volumetric response of clay skeleton: (a) improving the dilatancy prediction at low to high overconsolidation ratios (Section 2). An elasto-plastic constitutive model has been developed to account for this effect (Section 3.2.); (b) modelling of swelling effects (Section 2.5). A preliminary interpretative model for swelling prediction has been developed (Section 2.5). The application part consisted in interpreting the experimental results obtained for Boom clay to calibrate a set of constants (Section 3) for performing numerical analyses (Section 4) for the thermomechanical model already calibrated for Boom clay (Appendix). Interpretation of the tests required an assessment of influence of the strong anisotropy effects revealed by Boom clay on the basis of an interpretative model characterized by a kinematic hardening plasticity and coupled elasticity (section 3)

  7. Specific and generic stem biomass and volume models of tree species in a West African tropical semi-deciduous forest

    DEFF Research Database (Denmark)

    Goussanou, Cédric A.; Guendehou, Sabin; Assogbadjo, Achille E.

    2016-01-01

    The quantification of the contribution of tropical forests to global carbon stocks and climate change mitigation requires availability of data and tools such as allometric equations. This study made available volume and biomass models for eighteen tree species in a semi-deciduous tropical forest...... enabled to conclude that the non-destructive sampling was a good approach to determining reliable basic wood density. The comparative analysis of species-specific models in this study with selected generic models for tropical forests indicated low probability to identify effective generic models with good...

  8. Quantitative Analysis of Variability and Uncertainty in Environmental Data and Models. Volume 1. Theory and Methodology Based Upon Bootstrap Simulation

    Energy Technology Data Exchange (ETDEWEB)

    Frey, H. Christopher [North Carolina State University, Raleigh, NC (United States); Rhodes, David S. [North Carolina State University, Raleigh, NC (United States)

    1999-04-30

    This is Volume 1 of a two-volume set of reports describing work conducted at North Carolina State University sponsored by Grant Number DE-FG05-95ER30250 by the U.S. Department of Energy. The title of the project is “Quantitative Analysis of Variability and Uncertainty in Acid Rain Assessments.” The work conducted under sponsorship of this grant pertains primarily to two main topics: (1) development of new methods for quantitative analysis of variability and uncertainty applicable to any type of model; and (2) analysis of variability and uncertainty in the performance, emissions, and cost of electric power plant combustion-based NOx control technologies. These two main topics are reported separately in Volumes 1 and 2.

  9. Including the effects of elastic compressibility and volume changes in geodynamical modeling of crust-lithosphere-mantle deformation

    Science.gov (United States)

    de Monserrat, Albert; Morgan, Jason P.

    2016-04-01

    Materials in Earth's interior are exposed to thermomechanical (e.g. variations in stress/pressure and temperature) and chemical (e.g. phase changes, serpentinization, melting) processes that are associated with volume changes. Most geodynamical codes assume the incompressible Boussinesq approximation, where changes in density due to temperature or phase change effect buoyancy, yet volumetric changes are not allowed, and mass is not locally conserved. Elastic stresses induced by volume changes due to thermal expansion, serpentinization, and melt intrusion should cause 'cold' rocks to brittlely fail at ~1% strain. When failure/yielding is an important rheological feature, we think it plausible that volume-change-linked stresses may have a significant influence on the localization of deformation. Here we discuss a new Lagrangian formulation for "elasto-compressible -visco-plastic" flow. In this formulation, the continuity equation has been generalised from a Boussinesq incompressible formulation to include recoverable, elastic, volumetric deformations linked to the local state of mean compressive stress. This formulation differs from the 'anelastic approximation' used in compressible viscous flow in that pressure- and temperature- dependent volume changes are treated as elastic deformation for a given pressure, temperature, and composition/phase. This leads to a visco-elasto-plastic formulation that can model the effects of thermal stresses, pressure-dependent volume changes, and local phase changes. We use a modified version of the (Miliman-based) FEM code M2TRI to run a set of numerical experiments for benchmarking purposes. Three benchmarks are being used to assess the accuracy of this formulation: (1) model the effects on density of a compressible mantle under the influence of gravity; (2) model the deflection of a visco-elastic beam under the influence of gravity, and its recovery when gravitational loading is artificially removed; (3) Modelling the stresses

  10. A novel convolution-based approach to address ionization chamber volume averaging effect in model-based treatment planning systems

    Science.gov (United States)

    Barraclough, Brendan; Li, Jonathan G.; Lebron, Sharon; Fan, Qiyong; Liu, Chihray; Yan, Guanghua

    2015-08-01

    The ionization chamber volume averaging effect is a well-known issue without an elegant solution. The purpose of this study is to propose a novel convolution-based approach to address the volume averaging effect in model-based treatment planning systems (TPSs). Ionization chamber-measured beam profiles can be regarded as the convolution between the detector response function and the implicit real profiles. Existing approaches address the issue by trying to remove the volume averaging effect from the measurement. In contrast, our proposed method imports the measured profiles directly into the TPS and addresses the problem by reoptimizing pertinent parameters of the TPS beam model. In the iterative beam modeling process, the TPS-calculated beam profiles are convolved with the same detector response function. Beam model parameters responsible for the penumbra are optimized to drive the convolved profiles to match the measured profiles. Since the convolved and the measured profiles are subject to identical volume averaging effect, the calculated profiles match the real profiles when the optimization converges. The method was applied to reoptimize a CC13 beam model commissioned with profiles measured with a standard ionization chamber (Scanditronix Wellhofer, Bartlett, TN). The reoptimized beam model was validated by comparing the TPS-calculated profiles with diode-measured profiles. Its performance in intensity-modulated radiation therapy (IMRT) quality assurance (QA) for ten head-and-neck patients was compared with the CC13 beam model and a clinical beam model (manually optimized, clinically proven) using standard Gamma comparisons. The beam profiles calculated with the reoptimized beam model showed excellent agreement with diode measurement at all measured geometries. Performance of the reoptimized beam model was comparable with that of the clinical beam model in IMRT QA. The average passing rates using the reoptimized beam model increased substantially from 92.1% to

  11. Modelling dynamic liquid-gas systems: Extensions to the volume-of-fluid solver

    CSIR Research Space (South Africa)

    Heyns, Johan A

    2013-06-01

    Full Text Available onboard air- and spacecraft or liquid natural gas on tankers. As part of the development three extensions are considered: Firstly, a revised surface capturing formulation is proposed; secondly, a new weakly compressible volume-of-fluid formulation...

  12. A SUB-GRID VOLUME-OF-FLUIDS (VOF) MODEL FOR MIXING IN RESOLVED SCALE AND IN UNRESOLVED SCALE COMPUTATIONS

    Energy Technology Data Exchange (ETDEWEB)

    VOLD, ERIK L. [Los Alamos National Laboratory; SCANNAPIECO, TONY J. [Los Alamos National Laboratory

    2007-10-16

    A sub-grid mix model based on a volume-of-fluids (VOF) representation is described for computational simulations of the transient mixing between reactive fluids, in which the atomically mixed components enter into the reactivity. The multi-fluid model allows each fluid species to have independent values for density, energy, pressure and temperature, as well as independent velocities and volume fractions. Fluid volume fractions are further divided into mix components to represent their 'mixedness' for more accurate prediction of reactivity. Time dependent conversion from unmixed volume fractions (denoted cf) to atomically mixed (af) fluids by diffusive processes is represented in resolved scale simulations with the volume fractions (cf, af mix). In unresolved scale simulations, the transition to atomically mixed materials begins with a conversion from unmixed material to a sub-grid volume fraction (pf). This fraction represents the unresolved small scales in the fluids, heterogeneously mixed by turbulent or multi-phase mixing processes, and this fraction then proceeds in a second step to the atomically mixed fraction by diffusion (cf, pf, af mix). Species velocities are evaluated with a species drift flux, {rho}{sub i}u{sub di} = {rho}{sub i}(u{sub i}-u), used to describe the fluid mixing sources in several closure options. A simple example of mixing fluids during 'interfacial deceleration mixing with a small amount of diffusion illustrates the generation of atomically mixed fluids in two cases, for resolved scale simulations and for unresolved scale simulations. Application to reactive mixing, including Inertial Confinement Fusion (ICF), is planned for future work.

  13. Computational Methods for Protein Structure Prediction and Modeling Volume 2: Structure Prediction

    CERN Document Server

    Xu, Ying; Liang, Jie

    2007-01-01

    Volume 2 of this two-volume sequence focuses on protein structure prediction and includes protein threading, De novo methods, applications to membrane proteins and protein complexes, structure-based drug design, as well as structure prediction as a systems problem. A series of appendices review the biological and chemical basics related to protein structure, computer science for structural informatics, and prerequisite mathematics and statistics.

  14. Normal tissue complication probabilities: dependence on choice of biological model and dose-volume histogram reduction scheme

    International Nuclear Information System (INIS)

    Moiseenko, Vitali; Battista, Jerry; Van Dyk, Jake

    2000-01-01

    Purpose: To evaluate the impact of dose-volume histogram (DVH) reduction schemes and models of normal tissue complication probability (NTCP) on ranking of radiation treatment plans. Methods and Materials: Data for liver complications in humans and for spinal cord in rats were used to derive input parameters of four different NTCP models. DVH reduction was performed using two schemes: 'effective volume' and 'preferred Lyman'. DVHs for competing treatment plans were derived from a sample DVH by varying dose uniformity in a high dose region so that the obtained cumulative DVHs intersected. Treatment plans were ranked according to the calculated NTCP values. Results: Whenever the preferred Lyman scheme was used to reduce the DVH, competing plans were indistinguishable as long as the mean dose was constant. The effective volume DVH reduction scheme did allow us to distinguish between these competing treatment plans. However, plan ranking depended on the radiobiological model used and its input parameters. Conclusions: Dose escalation will be a significant part of radiation treatment planning using new technologies, such as 3-D conformal radiotherapy and tomotherapy. Such dose escalation will depend on how the dose distributions in organs at risk are interpreted in terms of expected complication probabilities. The present study indicates considerable variability in predicted NTCP values because of the methods used for DVH reduction and radiobiological models and their input parameters. Animal studies and collection of standardized clinical data are needed to ascertain the effects of non-uniform dose distributions and to test the validity of the models currently in use

  15. Early maternal alcohol consumption alters hippocampal DNA methylation, gene expression and volume in a mouse model.

    Directory of Open Access Journals (Sweden)

    Heidi Marjonen

    Full Text Available The adverse effects of alcohol consumption during pregnancy are known, but the molecular events that lead to the phenotypic characteristics are unclear. To unravel the molecular mechanisms, we have used a mouse model of gestational ethanol exposure, which is based on maternal ad libitum ingestion of 10% (v/v ethanol for the first 8 days of gestation (GD 0.5-8.5. Early neurulation takes place by the end of this period, which is equivalent to the developmental stage early in the fourth week post-fertilization in human. During this exposure period, dynamic epigenetic reprogramming takes place and the embryo is vulnerable to the effects of environmental factors. Thus, we hypothesize that early ethanol exposure disrupts the epigenetic reprogramming of the embryo, which leads to alterations in gene regulation and life-long changes in brain structure and function. Genome-wide analysis of gene expression in the mouse hippocampus revealed altered expression of 23 genes and three miRNAs in ethanol-exposed, adolescent offspring at postnatal day (P 28. We confirmed this result by using two other tissues, where three candidate genes are known to express actively. Interestingly, we found a similar trend of upregulated gene expression in bone marrow and main olfactory epithelium. In addition, we observed altered DNA methylation in the CpG islands upstream of the candidate genes in the hippocampus. Our MRI study revealed asymmetry of brain structures in ethanol-exposed adult offspring (P60: we detected ethanol-induced enlargement of the left hippocampus and decreased volume of the left olfactory bulb. Our study indicates that ethanol exposure in early gestation can cause changes in DNA methylation, gene expression, and brain structure of offspring. Furthermore, the results support our hypothesis of early epigenetic origin of alcohol-induced disorders: changes in gene regulation may have already taken place in embryonic stem cells and therefore can be seen in

  16. BPACK -- A computer model package for boiler reburning/co-firing performance evaluations. User`s manual, Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    Wu, K.T.; Li, B.; Payne, R.

    1992-06-01

    This manual presents and describes a package of computer models uniquely developed for boiler thermal performance and emissions evaluations by the Energy and Environmental Research Corporation. The model package permits boiler heat transfer, fuels combustion, and pollutant emissions predictions related to a number of practical boiler operations such as fuel-switching, fuels co-firing, and reburning NO{sub x} reductions. The models are adaptable to most boiler/combustor designs and can handle burner fuels in solid, liquid, gaseous, and slurried forms. The models are also capable of performing predictions for combustion applications involving gaseous-fuel reburning, and co-firing of solid/gas, liquid/gas, gas/gas, slurry/gas fuels. The model package is conveniently named as BPACK (Boiler Package) and consists of six computer codes, of which three of them are main computational codes and the other three are input codes. The three main codes are: (a) a two-dimensional furnace heat-transfer and combustion code: (b) a detailed chemical-kinetics code; and (c) a boiler convective passage code. This user`s manual presents the computer model package in two volumes. Volume 1 describes in detail a number of topics which are of general users` interest, including the physical and chemical basis of the models, a complete description of the model applicability, options, input/output, and the default inputs. Volume 2 contains a detailed record of the worked examples to assist users in applying the models, and to illustrate the versatility of the codes.

  17. Models of cognitive behavior in nuclear power plant personnel. A feasibility study: summary of results. Volume 1

    International Nuclear Information System (INIS)

    Woods, D.D.; Roth, E.M.; Hanes, L.F.

    1986-07-01

    This report summarizes the results of a feasibility study to determine if the current state of models of human cognitive activities can serve as the basis for improved techniques for predicting human error in nuclear power plants emergency operations. Based on the answer to this question, two subsequent phases of research are planned. Phase II is to develop a model of cognitive activities, and Phase III is to test the model. The feasibility study included an analysis of the cognitive activities that occur in emergency operations and an assessment of the modeling concepts/tools available to capture these cognitive activities. The results indicated that a symbolic processing (or artificial intelligence) model of cognitive activities in nuclear power plants is both desirable and feasible. This cognitive model can be built upon the computational framework provided by an existing artificial intelligence system for medical problem solving, called Caduceus. The resulting cognitive model will increase the capability to capture the human contribution to risk in probabilistic risk assessment studies. Volume 1 summarizes the major findings and conclusions of the study. Volume 2 provides a complete description of the methods and results, including a synthesis of the cognitive activities that occur during emergency operations, and a literature review on cognitive modeling relevant to nuclear power plants. 19 refs

  18. Projection models for health effects assessment in populations exposed to radioactive and nonradioactive pollutants. Volume IV. SPAHR user's guide

    International Nuclear Information System (INIS)

    Collins, J.J.; Lundy, R.T.

    1982-09-01

    The Simulation Package for the Analysis of Health Risk (SPAHR) is a computer software package based upon a demographic model for health risk projections. The model extends several health risk projection models by making realistic assumptions about the population at risk, and thus represents a distinct improvement over previous models. Complete documentation for use of SPAHR is contained in this five-volume publication. The demographic model in SPAHR estimates population response to environmental toxic exposures. Latency of response, changing dose level over time, competing risks from other causes of death, and population structure can be incorporated into SPAHR to project health risks. Risks are measured by morbid years, number of deaths, and loss of life expectancy. Comparisons of estimates of excess deaths demonstrate that previous health risk projection models may have underestimated excess deaths by a factor of from 2 to 10, depending on the pollutant and the exposure scenario. The software supporting the use of the demographic model is designed to be user oriented. Complex risk projections are made by responding to a series of prompts generated by the package. The flexibility and ease of use of SPAHR make it an important contribution to existing models and software packages. This volume gives the more advanced user of the SPAHR computer package the information required to create tailor-made programs for addressing specific issues not covered by the three interactive packages. It assumes that the user is familiar with the concepts and terms relating to demography and health risk assessment

  19. A model to estimate volume change due to radiolytic gas bubbles and thermal expansion in solution reactors

    International Nuclear Information System (INIS)

    Souto, F.J.; Heger, A.S.

    2001-01-01

    To investigate the effects of radiolytic gas bubbles and thermal expansion on the steady-state operation of solution reactors at the power level required for the production of medical isotopes, a calculational model has been developed. To validate this model, including its principal hypotheses, specific experiments at the Los Alamos National Laboratory SHEBA uranyl fluoride solution reactor were conducted. The following sections describe radiolytic gas generation in solution reactors, the equations to estimate the fuel solution volume change due to radiolytic gas bubbles and thermal expansion, the experiments conducted at SHEBA, and the comparison of experimental results and model calculations. (author)

  20. A model to estimate volume change due to radiolytic gas bubbles and thermal expansion in solution reactors

    Energy Technology Data Exchange (ETDEWEB)

    Souto, F.J. [NIS-6: Advanced Nuclear Technology, Los Alamos National Lab., Los Alamos, NM (United States); Heger, A.S. [ESA-EA: Engineering Sciences and Application, Los Alamos National Lab., Los Alamos, NM (United States)

    2001-07-01

    To investigate the effects of radiolytic gas bubbles and thermal expansion on the steady-state operation of solution reactors at the power level required for the production of medical isotopes, a calculational model has been developed. To validate this model, including its principal hypotheses, specific experiments at the Los Alamos National Laboratory SHEBA uranyl fluoride solution reactor were conducted. The following sections describe radiolytic gas generation in solution reactors, the equations to estimate the fuel solution volume change due to radiolytic gas bubbles and thermal expansion, the experiments conducted at SHEBA, and the comparison of experimental results and model calculations. (author)

  1. Characterization of Mixtures. Part 2: QSPR Models for Prediction of Excess Molar Volume and Liquid Density Using Neural Networks.

    Science.gov (United States)

    Ajmani, Subhash; Rogers, Stephen C; Barley, Mark H; Burgess, Andrew N; Livingstone, David J

    2010-09-17

    In our earlier work, we have demonstrated that it is possible to characterize binary mixtures using single component descriptors by applying various mixing rules. We also showed that these methods were successful in building predictive QSPR models to study various mixture properties of interest. Here in, we developed a QSPR model of an excess thermodynamic property of binary mixtures i.e. excess molar volume (V(E) ). In the present study, we use a set of mixture descriptors which we earlier designed to specifically account for intermolecular interactions between the components of a mixture and applied successfully to the prediction of infinite-dilution activity coefficients using neural networks (part 1 of this series). We obtain a significant QSPR model for the prediction of excess molar volume (V(E) ) using consensus neural networks and five mixture descriptors. We find that hydrogen bond and thermodynamic descriptors are the most important in determining excess molar volume (V(E) ), which is in line with the theory of intermolecular forces governing excess mixture properties. The results also suggest that the mixture descriptors utilized herein may be sufficient to model a wide variety of properties of binary and possibly even more complex mixtures. Copyright © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  2. The effect of blood volume loss on cardiovascular response to lower body negative pressure using a mathematical model

    Science.gov (United States)

    Karam, E. H.; Srinivasan, R. S.; Charles, J. B.; Fortney, S. M.

    1994-01-01

    Different mathematical models of varying complexity have been proposed in recent years to study the cardiovascular (CV) system. However, only a few of them specifically address the response to lower body negative pressure (LBNP), a stress that can be applied in weightlessness to predict changes in orthostatic tolerance. Also, the simulated results produced by these models agree only partially with experimental observations. In contrast, the model proposed by Melchior et al., and modified by Karam et al. is a simple representation of the CV system capable of accurately reproducing observed LBNP responses up to presyncopal levels. There are significant changes in LBNP response due to a loss of blood volume and other alterations that occur in weightlessness and related one-g conditions such as bedrest. A few days of bedrest can cause up to 15% blood volume loss (BVL), with consequent decreases in both stroke volume and cardiac output, and increases in heart rate, mean arterial pressure, and total peripheral resistance. These changes are more pronounced at higher levels of LBNP. This paper presents the results of a simulation study using our CV model to examine the effect of BVL on LBNP response.

  3. 3D CT modeling of hepatic vessel architecture and volume calculation in living donated liver transplantation

    International Nuclear Information System (INIS)

    Frericks, Bernd B.; Caldarone, Franco C.; Savellano, Dagmar Hoegemann; Stamm, Georg; Kirchhoff, Timm D.; Shin, Hoen-Oh; Galanski, Michael; Nashan, Bjoern; Klempnauer, Juergen; Schenk, Andrea; Selle, Dirk; Spindler, Wolf; Peitgen, Heinz-Otto

    2004-01-01

    The aim of this study was to evaluate a software tool for non-invasive preoperative volumetric assessment of potential donors in living donated liver transplantation (LDLT). Biphasic helical CT was performed in 56 potential donors. Data sets were post-processed using a non-commercial software tool for segmentation, volumetric analysis and visualisation of liver segments. Semi-automatic definition of liver margins allowed the segmentation of parenchyma. Hepatic vessels were delineated using a region-growing algorithm with automatically determined thresholds. Volumes and shapes of liver segments were calculated automatically based on individual portal-venous branches. Results were visualised three-dimensionally and statistically compared with conventional volumetry and the intraoperative findings in 27 transplanted cases. Image processing was easy to perform within 23 min. Of the 56 potential donors, 27 were excluded from LDLT because of inappropriate liver parenchyma or vascular architecture. Two recipients were not transplanted due to poor clinical conditions. In the 27 transplanted cases, preoperatively visualised vessels were confirmed, and only one undetected accessory hepatic vein was revealed. Calculated graft volumes were 1110±180 ml for right lobes, 820 ml for the left lobe and 270±30 ml for segments II+III. The calculated volumes and intraoperatively measured graft volumes correlated significantly. No significant differences between the presented automatic volumetry and the conventional volumetry were observed. A novel image processing technique was evaluated which allows a semi-automatic volume calculation and 3D visualisation of the different liver segments. (orig.)

  4. A Volume Model for Urban Heat Island Based on Remote Sensing Imagery and Its Application: A Case Study in Beijing

    Science.gov (United States)

    Zhou, J.; Chen, Y. H.; Li, J.; Weng, Q. H.

    2007-12-01

    Along with urbanization, urban heat island (UHI) has become one of the most serious urban problems, because of its impacts on the urban microclimate, air quality, energy consuming, public health and so on. With the advent of thermal remote sensing technology, remote observations of UHIs become the focus of urban remote sensing. While some progresses have been made by scientists, remote sensing study of UHI has been slow to advance qualitative description of thermal patterns and simple correlations. As a common indicator of UHI, magnitude is often used to describe the degree of UHI occurrence. In order to develop a more quantitative and more effective indicator for UHI dynamic monitoring at regional scale, deriving its spatial feature and facilitating the comparisons between different UHIs occur at different time or different areas based on remote sensing imageries, this paper proposes a new parameter named UHI volume to integrate UHI magnitude and extent effectively. After the subtraction of the rural contribution in the land surface temperature (LST) image, the isolated UHI signature is fitted using a least-squares Gaussian surface and then the UHI volume is calculated as a double integral of the UHI signature function over its footprint. This study investigates the applicability of this volume model based on examination of thirty EOS-Terra MODIS level 1B imageries of Beijing City, China, acquired between 2004~2006. These imageries include fifteen nighttime scenes, with their corresponding daytime scenes. Firstly, the resampled digital elevation model (DEM) data, the normalized difference vegetation index (NDVI) and the modified normalized difference water index (MNDWI) are used to extract the urban areas. Secondly, a simplified method is performed to retrieve the land surface temperature from MODIS channel 31 and channel 32. Thirdly, four transects at different directions including N-S, W-E, NW-SE and NE-SW are selected to detect the UHIs to ensure the

  5. A hybrid finite-volume and finite difference scheme for depth-integrated non-hydrostatic model

    Science.gov (United States)

    Yin, Jing; Sun, Jia-wen; Wang, Xing-gang; Yu, Yong-hai; Sun, Zhao-chen

    2017-06-01

    A depth-integrated, non-hydrostatic model with hybrid finite difference and finite volume numerical algorithm is proposed in this paper. By utilizing a fraction step method, the governing equations are decomposed into hydrostatic and non-hydrostatic parts. The first part is solved by using the finite volume conservative discretization method, whilst the latter is considered by solving discretized Poisson-type equations with the finite difference method. The second-order accuracy, both in time and space, of the finite volume scheme is achieved by using an explicit predictor-correction step and linear construction of variable state in cells. The fluxes across the cell faces are computed in a Godunov-based manner by using MUSTA scheme. Slope and flux limiting technique is used to equip the algorithm with total variation dimensioning property for shock capturing purpose. Wave breaking is treated as a shock by switching off the non-hydrostatic pressure in the steep wave front locally. The model deals with moving wet/dry front in a simple way. Numerical experiments are conducted to verify the proposed model.

  6. Artificial neural network modeling for reforestation design through the dominant trees bole-volume estimation

    NARCIS (Netherlands)

    Diamantopoulou, Maria J.; Milios, Elias; Doganos, Dimitrios; Bistinas, Ioannis

    2009-01-01

    In the management of restoration reforestations or recreational reforestations of trees, the density of the planted trees and the site conditions can influence the growth and bole volume of the dominant tree. The ability to influence growth of these trees in a reforestation contributes greatly to

  7. Statistical model for grain boundary and grain volume oxidation kinetics in UO2 spent fuel

    International Nuclear Information System (INIS)

    Stout, R.B.; Shaw, H.F.; Einziger, R.E.

    1989-09-01

    This paper addresses statistical characteristics for the simplest case of grain boundary/grain volume oxidation kinetics of UO 2 to U 3 O 7 for a fragment of a spent fuel pellet. It also presents a limited discussion of future extensions to this simple case to represent the more complex cases of oxidation kinetics in spent fuels. 17 refs., 1 fig

  8. A model for calculating eruptive volumes for monogenetic volcanoes — Implication for the Quaternary Auckland Volcanic Field, New Zealand

    Science.gov (United States)

    Kereszturi, Gábor; Németh, Károly; Cronin, Shane J.; Agustín-Flores, Javier; Smith, Ian E. M.; Lindsay, Jan

    2013-10-01

    Monogenetic basaltic volcanism is characterised by a complex array of behaviours in the spatial distribution of magma output and also temporal variability in magma flux and eruptive frequency. Investigating this in detail is hindered by the difficulty in evaluating ages of volcanic events as well as volumes erupted in each volcano. Eruptive volumes are an important input parameter for volcanic hazard assessment and may control eruptive scenarios, especially transitions between explosive and effusive behaviour and the length of eruptions. Erosion, superposition and lack of exposure limit the accuracy of volume determination, even for very young volcanoes. In this study, a systematic volume estimation model is developed and applied to the Auckland Volcanic Field in New Zealand. In this model, a basaltic monogenetic volcano is categorised in six parts. Subsurface portions of volcanoes, such as diatremes beneath phreatomagmatic volcanoes, or crater infills, are approximated by geometrical considerations, based on exposed analogue volcanoes. Positive volcanic landforms, such as scoria/spatter cones, tephras rings and lava flow, were defined by using a Light Detection and Ranging (LiDAR) survey-based Digital Surface Model (DSM). Finally, the distal tephra associated with explosive eruptions was approximated using published relationships that relate original crater size to ejecta volumes. Considering only those parts with high reliability, the overall magma output (converted to Dense Rock Equivalent) for the post-250 ka active Auckland Volcanic Field in New Zealand is a minimum of 1.704 km3. This is made up of 1.329 km3 in lava flows, 0.067 km3 in phreatomagmatic crater lava infills, 0.090 km3 within tephra/tuff rings, 0.112 km3 inside crater lava infills, and 0.104 km3 within scoria cones. Using the minimum eruptive volumes, the spatial and temporal magma fluxes are estimated at 0.005 km3/km2 and 0.007 km3/ka. The temporal-volumetric evolution of Auckland is

  9. Preliminary performance assessment for the Waste Isolation Pilot Plant, December 1992. Volume 3, Model parameters: Sandia WIPP Project

    Energy Technology Data Exchange (ETDEWEB)

    1992-12-29

    This volume documents model parameters chosen as of July 1992 that were used by the Performance Assessment Department of Sandia National Laboratories in its 1992 preliminary performance assessment of the Waste Isolation Pilot Plant (WIPP). Ranges and distributions for about 300 modeling parameters in the current secondary data base are presented in tables for the geologic and engineered barriers, global materials (e.g., fluid properties), and agents that act upon the WIPP disposal system such as climate variability and human-intrusion boreholes. The 49 parameters sampled in the 1992 Preliminary Performance Assessment are given special emphasis with tables and graphics that provide insight and sources of data for each parameter.

  10. Multi-model ensemble estimation of volume transport through the straits of the East/Japan Sea

    Science.gov (United States)

    Han, Sooyeon; Hirose, Naoki; Usui, Norihisa; Miyazawa, Yasumasa

    2016-01-01

    The volume transports measured at the Korea/Tsushima, Tsugaru, and Soya/La Perouse Straits remain quantitatively inconsistent. However, data assimilation models at least provide a self-consistent budget despite subtle differences among the models. This study examined the seasonal variation of the volume transport using the multiple linear regression and ridge regression of multi-model ensemble (MME) methods to estimate more accurately transport at these straits by using four different data assimilation models. The MME outperformed all of the single models by reducing uncertainties, especially the multicollinearity problem with the ridge regression. However, the regression constants turned out to be inconsistent with each other if the MME was applied separately for each strait. The MME for a connected system was thus performed to find common constants for these straits. The estimation of this MME was found to be similar to the MME result of sea level difference (SLD). The estimated mean transport (2.43 Sv) was smaller than the measurement data at the Korea/Tsushima Strait, but the calibrated transport of the Tsugaru Strait (1.63 Sv) was larger than the observed data. The MME results of transport and SLD also suggested that the standard deviation (STD) of the Korea/Tsushima Strait is larger than the STD of the observation, whereas the estimated results were almost identical to that observed for the Tsugaru and Soya/La Perouse Straits. The similarity between MME results enhances the reliability of the present MME estimation.

  11. High-order accurate finite-volume formulations for the pressure gradient force in layered ocean models

    Science.gov (United States)

    Engwirda, Darren; Kelley, Maxwell; Marshall, John

    2017-08-01

    Discretisation of the horizontal pressure gradient force in layered ocean models is a challenging task, with non-trivial interactions between the thermodynamics of the fluid and the geometry of the layers often leading to numerical difficulties. We present two new finite-volume schemes for the pressure gradient operator designed to address these issues. In each case, the horizontal acceleration is computed as an integration of the contact pressure force that acts along the perimeter of an associated momentum control-volume. A pair of new schemes are developed by exploring different control-volume geometries. Non-linearities in the underlying equation-of-state definitions and thermodynamic profiles are treated using a high-order accurate numerical integration framework, designed to preserve hydrostatic balance in a non-linear manner. Numerical experiments show that the new methods achieve high levels of consistency, maintaining hydrostatic and thermobaric equilibrium in the presence of strongly-sloping layer geometries, non-linear equations-of-state and non-uniform vertical stratification profiles. These results suggest that the new pressure gradient formulations may be appropriate for general circulation models that employ hybrid vertical coordinates and/or terrain-following representations.

  12. Renewable Resources: a national catalog of model projects. Volume 1. Northeast Solar Energy Center Region

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-07-01

    This compilation of diverse conservation and renewable energy projects across the United States was prepared through the enthusiastic participation of solar and alternate energy groups from every state and region. Compiled and edited by the Center for Renewable Resources, these projects reflect many levels of innovation and technical expertise. In many cases, a critique analysis is presented of how projects performed and of the institutional conditions associated with their success or failure. Some 2000 projects are included in this compilation; most have worked, some have not. Information about all is presented to aid learning from these experiences. The four volumes in this set are arranged in state sections by geographic region, coinciding with the four Regional Solar Energy Centers. The table of contents is organized by project category so that maximum cross-referencing may be obtained. This volume includes information on the Northeast Solar Energy Center Region. (WHK).

  13. Renewable Resources: a national catalog of model projects. Volume 3. Southern Solar Energy Center Region

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-07-01

    This compilation of diverse conservation and renewable energy projects across the United States was prepared through the enthusiastic participation of solar and alternate energy groups from every state and region. Compiled and edited by the Center for Renewable Resources, these projects reflect many levels of innovation and technical expertise. In many cases, a critique analysis is presented of how projects performed and of the institutional conditions associated with their success or failure. Some 2000 projects are included in this compilation; most have worked, some have not. Information about all is presented to aid learning from these experiences. The four volumes in this set are arranged in state sections by geographic region, coinciding with the four Regional Solar Energy Centers. The table of contents is organized by project category so that maximum cross-referencing may be obtained. This volume includes information on the Southern Solar Energy Center Region. (WHK)

  14. Renewable Resources: a national catalog of model projects. Volume 4. Western Solar Utilization Network Region

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-07-01

    This compilation of diverse conservation and renewable energy projects across the United States was prepared through the enthusiastic participation of solar and alternate energy groups from every state and region. Compiled and edited by the Center for Renewable Resources, these projects reflect many levels of innovation and technical expertise. In many cases, a critique analysis is presented of how projects performed and of the institutional conditions associated with their success or failure. Some 2000 projects are included in this compilation; most have worked, some have not. Information about all is presented to aid learning from these experiences. The four volumes in this set are arranged in state sections by geographic region, coinciding with the four Regional Solar Energy Centers. The table of contents is organized by project category so that maximum cross-referencing may be obtained. This volume includes information on the Western Solar Utilization Network Region. (WHK)

  15. An Inverse Model for Calculation of Global Volume Transport from Wind and Hydrographic Data

    Science.gov (United States)

    2007-01-01

    differentiation of (22) with respect to x gives the volume transport vorticity equation, j2C ¼ b Ah ðV−Vden−VbÞ− 1Ahq0 Asy Ax − Asx Ay þ AQ2 Ax − AQ1 Ay...q0 : ð31Þ Similarly, (30) becomes bðV−Vden−VbÞ ¼ 1q0 Asy Ax − Asx Ay ; ð32Þ which is the Sverdrup relation. In (31), (Uden, Vden) depend on

  16. Modeling the Effect of Glass Microballoon (GMB) Volume Fraction on Behavior of Sylgard/GMB Composites.

    Energy Technology Data Exchange (ETDEWEB)

    Brown, Judith Alice [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Long, Kevin Nicholas [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-05-01

    This work was done to support customer questions about whether a Sylgard/Glass Microballoon (GMB) potting material in current use could be replaced with pure Sylgard and if this would significantly change stresses imparted to internal components under thermal cycling conditions. To address these questions, we provide micromechanics analysis of Sylgard/GMB materials using both analytic composite theory and finite element simulations to better understand the role of the GMB volume fraction in determining thermal expansion coefficient, elastic constants, and behavior in both confined and unconfined compression boundary value problems. A key finding is that damage accumulation in the material from breakage of GMBs significantly limits the global stress magnitude and results in a plateau stress behavior over large ranges of compressive strain. The magnitude of this plateau stress is reduced with higher volume fractions of GMBs. This effect is particularly pronounced in confined compression, which we estimate bears the most similarity to the application of interest. This stress-limiting damage mechanism is not present in pure Sylgard, however, and the result is much higher stresses under confined compression. Thus, we recommend that some volume fraction greater than 10% GMBs be used for confined deformation applications.

  17. Urokinase receptor cleavage correlates with tumor volume in a transgenic mouse model of breast cancer

    DEFF Research Database (Denmark)

    Thurison, Tine; Almholt, Kasper; Gårdsvoll, Henrik

    2015-01-01

    PAR(I)]. The level of muPAR(I) is significantly increased in mammary tumor-bearing mice compared to controls and, notably, there is a strong correlation to tumor volume. In contrast, the tumor volume is only weakly correlated to the level of intact muPAR(I-III), indicating that cleavage of muPAR is a more specific...... marker for cancer than increased expression of muPAR per se. The levels of the muPAR forms are dramatically affected by in vivo challenge with a urokinase -blocking antibody, demonstrating a functional role of uPA in uPAR cleavage. The levels of the muPAR forms are, however, unaffected by u......PA-deficiency, suggesting that redundant proteases maintains the task of cleaving uPAR(I-III) when uPA is absent. Our findings emphasize the significance of the cleaved uPAR forms as cancer biomarkers. The strong correlation between muPAR(I) and the tumor volume in our experimental setup may motivate investigations...

  18. Industrial Sector Technology Use Model (ISTUM): industrial energy use in the United States, 1974-2000. Volume 1. Primary model documentation. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Bohn, Roger E.; Herod, J. Steven; Andrews, Gwen L.; Budzik, Philip M.; Eissenstat, Richard S.; Grossmann, John R.; Reiner, Gary M.; Roschke, Thomas E.; Shulman, Michael J.; Toppen, Timothy R.; Veno, William R.; Violette, Daniel M.; Smolinski, Michael D.; Habel, Deborah; Cook, Alvin E.

    1979-10-01

    ISTUM is designed to predict the commercial market penetration of various energy technologies in the industrial sector out to the year 2000. It is a refinement and further development of Market Oriented Program Planning Study task force in 1977. ISTUM assesses the comparative economic competitiveness of each technology and competes over 100 energy technologies - conventionals, fossil/energy, conservation, cogeneration, solar, and geothermal. A broad overview of the model, the solution of the model, and an in-depth discussion of strength and limitations of the model are provided in Volume I. (MCW)

  19. Estimation of Tumor Volumes by 11C-MeAIB and 18F-FDG PET in an Orthotopic Glioblastoma Rat Model

    DEFF Research Database (Denmark)

    Halle, Bo; Thisgaard, Helge; Hvidsten, Svend

    2015-01-01

    UNLABELLED: Brain tumor volume assessment is a major challenge. Molecular imaging using PET may be a promising option because it reflects the biologically active cells. We compared the agreement between PET- and histology-derived tumor volumes in an orthotopic glioblastoma rat model with a noninf...

  20. Glass Transition Temperature- and Specific Volume- Composition Models for Tellurite Glasses

    Energy Technology Data Exchange (ETDEWEB)

    Riley, Brian J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Vienna, John D. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2017-09-01

    This report provides models for predicting composition-properties for tellurite glasses, namely specific gravity and glass transition temperature. Included are the partial specific coefficients for each model, the component validity ranges, and model fit parameters.

  1. Generalization techniques to reduce the number of volume elements for terrain effect calculations in fully analytical gravitational modelling

    Science.gov (United States)

    Benedek, Judit; Papp, Gábor; Kalmár, János

    2018-04-01

    Beyond rectangular prism polyhedron, as a discrete volume element, can also be used to model the density distribution inside 3D geological structures. The calculation of the closed formulae given for the gravitational potential and its higher-order derivatives, however, needs twice more runtime than that of the rectangular prism computations. Although the more detailed the better principle is generally accepted it is basically true only for errorless data. As soon as errors are present any forward gravitational calculation from the model is only a possible realization of the true force field on the significance level determined by the errors. So if one really considers the reliability of input data used in the calculations then sometimes the "less" can be equivalent to the "more" in statistical sense. As a consequence the processing time of the related complex formulae can be significantly reduced by the optimization of the number of volume elements based on the accuracy estimates of the input data. New algorithms are proposed to minimize the number of model elements defined both in local and in global coordinate systems. Common gravity field modelling programs generate optimized models for every computation points ( dynamic approach), whereas the static approach provides only one optimized model for all. Based on the static approach two different algorithms were developed. The grid-based algorithm starts with the maximum resolution polyhedral model defined by 3-3 points of each grid cell and generates a new polyhedral surface defined by points selected from the grid. The other algorithm is more general; it works also for irregularly distributed data (scattered points) connected by triangulation. Beyond the description of the optimization schemes some applications of these algorithms in regional and local gravity field modelling are presented too. The efficiency of the static approaches may provide even more than 90% reduction in computation time in favourable

  2. Coupled Finite Volume Methods and Extended Finite Element Methods for the Dynamic Crack Propagation Modelling with the Pressurized Crack Surfaces

    Directory of Open Access Journals (Sweden)

    Shouyan Jiang

    2017-01-01

    Full Text Available We model the fluid flow within the crack as one-dimensional flow and assume that the flow is laminar; the fluid is incompressible and accounts for the time-dependent rate of crack opening. Here, we discretise the flow equation by finite volume methods. The extended finite element methods are used for solving solid medium with crack under dynamic loads. Having constructed the approximation of dynamic extended finite element methods, the derivation of governing equation for dynamic extended finite element methods is presented. The implicit time algorithm is elaborated for the time descritisation of dominant equation. In addition, the interaction integral method is given for evaluating stress intensity factors. Then, the coupling model for modelling hydraulic fracture can be established by the extended finite element methods and the finite volume methods. We compare our present numerical results with our experimental results for verifying the proposed model. Finally, we investigate the water pressure distribution along crack surface and the effect of water pressure distribution on the fracture property.

  3. Projection models for health-effects assessment in populations exposed to radioactive and nonradioactive pollutants. Volume I. Introduction to the SPAHR demographic model for health risk

    Energy Technology Data Exchange (ETDEWEB)

    Collins, J.J.; Lundy, R.T.; Grahn, D.; Ginevan, M.E.

    1982-09-01

    The Simulation Package for the Analysis of Health Risk (SPAHR) is a computer software package based upon a demographic model for health risk projections. The model extends several health risk projection models by making realistic assumptions about the population at risk, and thus represents a distinct improvement over previous models. Complete documentation for use of SPAHR is contained in this five-volume publication. The demographic model in SPAHR estimates population response to environmental toxic exposures. Latency of response, changing dose level over time, competing risks from other causes of death, and population structure can be incorporated into SPAHR to project health risks. Risks are measured by morbid years, number of deaths, and loss of life expectancy. Comparisons of estimates of excess deaths demonstrate that previous health risk projection models may have underestimated excess deaths by a factor of from 2 to 10, depending on the pollutant and the exposure scenario. The software supporting the use of the demographic model is designed to be user oriented. Complex risk projections are made by responding to a series of prompts generated by the package. The flexibility and ease of use of SPAHR make it an important contribution to existing models and software packages. The first volume presents the theory behind the SPAHR health risk projection model and several applications of the model to actual pollution episodes. The elements required for an effective health risk projection model are specified, and the models that have been used to date in health risk projections are outlined. These are compared with the demographic model, whose formulation is described in detail. Examples of the application of air pollution and radiation dose-response functions are included in order to demonstrate the estimation of future mortality and morbidity levels and the range of variation in excess deaths that occurs when populations structure is changed.

  4. Projection models for health-effects assessment in populations exposed to radioactive and nonradioactive pollutants. Volume I. Introduction to the SPAHR demographic model for health risk

    International Nuclear Information System (INIS)

    Collins, J.J.; Lundy, R.T.; Grahn, D.; Ginevan, M.E.

    1982-09-01

    The Simulation Package for the Analysis of Health Risk (SPAHR) is a computer software package based upon a demographic model for health risk projections. The model extends several health risk projection models by making realistic assumptions about the population at risk, and thus represents a distinct improvement over previous models. Complete documentation for use of SPAHR is contained in this five-volume publication. The demographic model in SPAHR estimates population response to environmental toxic exposures. Latency of response, changing dose level over time, competing risks from other causes of death, and population structure can be incorporated into SPAHR to project health risks. Risks are measured by morbid years, number of deaths, and loss of life expectancy. Comparisons of estimates of excess deaths demonstrate that previous health risk projection models may have underestimated excess deaths by a factor of from 2 to 10, depending on the pollutant and the exposure scenario. The software supporting the use of the demographic model is designed to be user oriented. Complex risk projections are made by responding to a series of prompts generated by the package. The flexibility and ease of use of SPAHR make it an important contribution to existing models and software packages. The first volume presents the theory behind the SPAHR health risk projection model and several applications of the model to actual pollution episodes. The elements required for an effective health risk projection model are specified, and the models that have been used to date in health risk projections are outlined. These are compared with the demographic model, whose formulation is described in detail. Examples of the application of air pollution and radiation dose-response functions are included in order to demonstrate the estimation of future mortality and morbidity levels and the range of variation in excess deaths that occurs when populations structure is changed

  5. Stochastic modelling of porosity using seismic impedances on a volume of chalk in the Dan Field

    Energy Technology Data Exchange (ETDEWEB)

    Vejbaek, O.V.

    1995-12-31

    Seismic impedances calculated from logs show very good correlation to log porosities in wells penetrating the chalk reservoir in the Dan Field, Danish North Sea. This is the basis for an attempt to use seismic impedances derived from inversion as soft data for geostatistical reservoir characterization. The study focusses on porosity description of the Maastrichtian chalk reservoir unit, laterally restricted to an area covered by a subset of a 3D seismic survey. This seismic volume was inverted using the ISIS software producing a volume of seismic impedances. Spatial porosity realizations are produced using a gaussian collocated co-simulation algorithm, where well log porosities constitute the hard data input and seismic impedances are the soft data input. The simulated volume measures 1400 m x 1525 m x 102 m and is oriented parallel to lines and cross lines in the seismic dataset. Simulated blocks measures 25 m x 25 m x 6 m equivalent to twice the line and trace spacing, and approximately equivalent to the seismic sample rate. The correlation coefficient between log porosities and impedances calculated from logs alone are shown to be misleading since they suggest unrealistic high coefficients. However, the actual data used, namely inversion derived impedances and log porosities, still show correlation coefficients in the order of -0,45, which is quite sufficient to make the inversion results very useful. It is remarkable that the calculated correlation coefficient is based on 15 wells, and the inversion is based on only one well. The negative correlation coefficient indicate that high impedances correspond to low porosities and vice-versa. The impedance data indicate the level of average porosities at locations between wells. The fine structure is produced by the geostatistic process, with averages constrained by seismic impedances. The seismic impedances derived from the inversion process are thus shown to constitute useful primary data to constrain reservoir

  6. Three-dimensional radiative transfer modeling using the control volume finite element method

    International Nuclear Information System (INIS)

    Grissa, H.; Askri, F.; Ben Salah, M.; Ben Nasrallah, S.

    2007-01-01

    In the present study, a three-dimensional algorithm for the treatment of radiative heat transfer in emitting, absorbing and scattering media is developed. The approach is based on the utilization of control volume finite element method (CVFEM) which, to the knowledge of the authors, is applied at the first time to 3D radiative heat transfer in participating media. The accuracy of the present algorithm is tested by comparing its predictions to other published works. Comparisons show that CVFEM produces good results. Moreover, this approach permits compatibility with other numerical methods used for computational fluids mechanics problems

  7. 3D Finite Volume Modeling of ENDE Using Electromagnetic T-Formulation

    Directory of Open Access Journals (Sweden)

    Yue Li

    2012-01-01

    Full Text Available An improved method which can analyze the eddy current density in conductor materials using finite volume method is proposed on the basis of Maxwell equations and T-formulation. The algorithm is applied to solve 3D electromagnetic nondestructive evaluation (E’NDE benchmark problems. The computing code is applied to study an Inconel 600 work piece with holes or cracks. The impedance change due to the presence of the crack is evaluated and compared with the experimental data of benchmark problems No. 1 and No. 2. The results show a good agreement between both calculated and measured data.

  8. Beam propagation modeling of modified volume Fresnel zone plates fabricated by femtosecond laser direct writing.

    Science.gov (United States)

    Srisungsitthisunti, Pornsak; Ersoy, Okan K; Xu, Xianfan

    2009-01-01

    Light diffraction by volume Fresnel zone plates (VFZPs) is simulated by the Hankel transform beam propagation method (Hankel BPM). The method utilizes circularly symmetric geometry and small step propagation to calculate the diffracted wave fields by VFZP layers. It is shown that fast and accurate diffraction results can be obtained with the Hankel BPM. The results show an excellent agreement with the scalar diffraction theory and the experimental results. The numerical method allows more comprehensive studies of the VFZP parameters to achieve higher diffraction efficiency.

  9. Carotid wall volume quantification from magnetic resonance images using deformable model fitting and learning-based correction of systematic errors

    International Nuclear Information System (INIS)

    Hameeteman, K; Niessen, W J; Klein, S; Van 't Klooster, R; Selwaness, M; Van der Lugt, A; Witteman, J C M

    2013-01-01

    We present a method for carotid vessel wall volume quantification from magnetic resonance imaging (MRI). The method combines lumen and outer wall segmentation based on deformable model fitting with a learning-based segmentation correction step. After selecting two initialization points, the vessel wall volume in a region around the bifurcation is automatically determined. The method was trained on eight datasets (16 carotids) from a population-based study in the elderly for which one observer manually annotated both the lumen and outer wall. An evaluation was carried out on a separate set of 19 datasets (38 carotids) from the same study for which two observers made annotations. Wall volume and normalized wall index measurements resulting from the manual annotations were compared to the automatic measurements. Our experiments show that the automatic method performs comparably to the manual measurements. All image data and annotations used in this study together with the measurements are made available through the website http://ergocar.bigr.nl. (paper)

  10. The model and the planning method of volume and variety assessment of innovative products in an industrial enterprise

    Science.gov (United States)

    Anisimov, V. G.; Anisimov, E. G.; Saurenko, T. N.; Sonkin, M. A.

    2017-01-01

    In the long term, the innovative development strategy efficiency is considered as the most crucial condition for assurance of economic system competitiveness in market conditions. It determines the problem relevance of such justification strategies with regard to specific systems features and conditions of their operation. The problem solution for industrial enterprises can be based on mathematical models of supporting the decision-making on the elements of the innovative manufacturing program. An optimization model and the planning method of innovative products volume and variety are suggested. The feature of the suggested model lies in the nonlinear nature of the objective function. It allows taking into consideration the law of diminishing marginal utility. The suggested method of optimization takes into account the system features and enables the effective implementation of manufacturing capabilities in modern conditions of production organization and sales in terms of market saturation.

  11. A mathematical model to predict the optimal test line location and sample volume for lateral flow immunoassays.

    Science.gov (United States)

    Ragavendar, M S; Anmol, Chopra M

    2012-01-01

    Lateral flow immunoassay (LFIA) platform is one of the most relevant technologies for screening and diagnosing clinical conditions. However due to low sensitivity and poor repeatability of the platform it has been used only for limited and non-critical tests. Mathematical models have been used to understand the principles of capillary flow and antibody antigen based immunoreactions in nitrocellulose membrane typically seen in LFIA. The model presented in this paper predicts the optimized location of test line on LFIA strip, sample volume and total reaction time that is needed to achieve the required sensitivity for different analytes on a case to case basis. The membrane properties like capillary flow time (s/cm), concentration and affinity constants of antibodies can be varied and the corresponding effect on strip design can be found. Hence this model can be used as a design tool to optimize the LFIA strip construction and reagent development processes.

  12. Understanding why the volume of suboxic waters does not increase over centuries of global warming in an Earth System Model

    Directory of Open Access Journals (Sweden)

    A. Gnanadesikan

    2012-03-01

    Full Text Available Global warming is expected to reduce oxygen solubility and vertical exchange in the ocean, changes which would be expected to result in an increase in the volume of hypoxic waters. A simulation made with a full Earth System model with dynamical atmosphere, ocean, sea ice and biogeochemical cycling (the Geophysical Fluid Dynamics Laboratory's Earth System Model 2.1 shows that this holds true if the condition for hypoxia is set relatively high. However, the volume of the most hypoxic (i.e., suboxic waters does not increase under global warming, as these waters actually become more oxygenated. We show that the rise in dissolved oxygen in the tropical Pacific is associated with a drop in ventilation time. A term-by-term analysis within the least oxygenated waters shows an increased supply of dissolved oxygen due to lateral diffusion compensating an increase in remineralization within these highly hypoxic waters. This lateral diffusive flux is the result of an increase of ventilation along the Chilean coast, as a drying of the region under global warming opens up a region of wintertime convection in our model. The results highlight the potential sensitivity of suboxic waters to changes in subtropical ventilation as well as the importance of constraining lateral eddy transport of dissolved oxygen in such waters.

  13. Heliox allows for lower minute volume ventilation in an animal model of ventilator-induced lung injury.

    Directory of Open Access Journals (Sweden)

    Charlotte J Beurskens

    Full Text Available BACKGROUND: Helium is a noble gas with a low density, allowing for lower driving pressures and increased carbon dioxide (CO2 diffusion. Since application of protective ventilation can be limited by the development of hypoxemia or acidosis, we hypothesized that therefore heliox facilitates ventilation in an animal model of ventilator-induced lung injury. METHODS: Sprague-Dawley rats (N=8 per group were mechanically ventilated with heliox (50% oxygen; 50% helium. Controls received a standard gas mixture (50% oxygen; 50% air. VILI was induced by application of tidal volumes of 15 mL kg(-1; lung protective ventilated animals were ventilated with 6 mL kg(-1. Respiratory parameters were monitored with a pneumotach system. Respiratory rate was adjusted to maintain arterial pCO2 within 4.5-5.5 kPa, according to hourly drawn arterial blood gases. After 4 hours, bronchoalveolar lavage fluid (BALF was obtained. Data are mean (SD. RESULTS: VILI resulted in an increase in BALF protein compared to low tidal ventilation (629 (324 vs. 290 (181 μg mL(-1; p<0.05 and IL-6 levels (640 (8.7 vs. 206 (8.7 pg mL(-1; p<0.05, whereas cell counts did not differ between groups after this short course of mechanical ventilation. Ventilation with heliox resulted in a decrease in mean respiratory minute volume ventilation compared to control (123 ± 0.6 vs. 146 ± 8.9 mL min(-1, P<0.001, due to a decrease in respiratory rate (22 (0.4 vs. 25 (2.1 breaths per minute; p<0.05, while pCO2 levels and tidal volumes remained unchanged, according to protocol. There was no effect of heliox on inspiratory pressure, while compliance was reduced. In this mild lung injury model, heliox did not exert anti-inflammatory effects. CONCLUSIONS: Heliox allowed for a reduction in respiratory rate and respiratory minute volume during VILI, while maintaining normal acid-base balance. Use of heliox may be a useful approach when protective tidal volume ventilation is limited by the development of

  14. RF model of the distribution system as a communication channel, phase 2. Volume 2: Task reports

    Science.gov (United States)

    Rustay, R. C.; Gajjar, J. T.; Rankin, R. W.; Wentz, R. C.; Wooding, R.

    1982-01-01

    Based on the established feasibility of predicting, via a model, the propagation of Power Line Frequency on radial type distribution feeders, verification studies comparing model predictions against measurements were undertaken using more complicated feeder circuits and situations. Detailed accounts of the major tasks are presented. These include: (1) verification of model; (2) extension, implementation, and verification of perturbation theory; (3) parameter sensitivity; (4) transformer modeling; and (5) compensation of power distribution systems for enhancement of power line carrier communication reliability.

  15. Advanced communication system time domain modeling techniques ASYSTD software description. Volume 2: Program support documentation

    Science.gov (United States)

    1972-01-01

    The theoretical basis for the ASYSTD program is discussed in detail. In addition, the extensive bibliography given in this document illustrates some of the extensive work accomplished in the area of time domain simulation. Additions have been in the areas of modeling and language program enhancements, orthogonal transform modeling, error analysis, general filter models, BER measurements, etc. Several models have been developed which utilize the COMSAT generated orthogonal transform algorithms.

  16. Modeling survival, yield, volume partitioning and their response to thinning for longleaf pine plantations

    Science.gov (United States)

    Carlos A. Gonzalez-Benecke; Salvador A. Gezan; Daniel J. Leduc; Timothy A. Martin; Wendell P. Cropper Jr; Lisa J Samuelson

    2012-01-01

    Longleaf pine (Pinus palustris Mill.) is an important tree species of the southeast U.S. Currently there is no comprehensive stand-level growth and yield model for the species. The model system described here estimates site index (SI) if dominant height (Hdom) and stand age are known (inversely, the model can project H

  17. Nonlinear flow model of multiple fractured horizontal wells with stimulated reservoir volume including the quadratic gradient term

    Science.gov (United States)

    Ren, Junjie; Guo, Ping

    2017-11-01

    The real fluid flow in porous media is consistent with the mass conservation which can be described by the nonlinear governing equation including the quadratic gradient term (QGT). However, most of the flow models have been established by ignoring the QGT and little work has been conducted to incorporate the QGT into the flow model of the multiple fractured horizontal (MFH) well with stimulated reservoir volume (SRV). This paper first establishes a semi-analytical model of an MFH well with SRV including the QGT. Introducing the transformed pressure and flow-rate function, the nonlinear model of a point source in a composite system including the QGT is linearized. Then the Laplace transform, principle of superposition, numerical discrete method, Gaussian elimination method and Stehfest numerical inversion are employed to establish and solve the seepage model of the MFH well with SRV. Type curves are plotted and the effects of relevant parameters are analyzed. It is found that the nonlinear effect caused by the QGT can increase the flow capacity of fluid flow and influence the transient pressure positively. The relevant parameters not only have an effect on the type curve but also affect the error in the pressure calculated by the conventional linear model. The proposed model, which is consistent with the mass conservation, reflects the nonlinear process of the real fluid flow, and thus it can be used to obtain more accurate transient pressure of an MFH well with SRV.

  18. Retrospective Validation of a Computer-Assisted Quantification Model of Intracerebral Hemorrhage Volume on Accuracy, Precision, and Acquisition Time, Compared with Standard ABC/2 Manual Volume Calculation.

    Science.gov (United States)

    Xue, W; Vegunta, S; Zwart, C M; Aguilar, M I; Patel, A C; Hoxworth, J M; Demaerschalk, B M; Mitchell, J R

    2017-08-01

    Intracerebral hemorrhage accounts for 6.5%-19.6% of all acute strokes. Initial intracerebral hemorrhage volume and expansion are both independent predictors of clinical outcomes and mortality. Therefore, a rapid, unbiased, and precise measurement of intracerebral hemorrhage volume is a key component of clinical management. The most commonly used method, ABC/2, results in overestimation. We developed an interactive segmentation program, SegTool, using a novel graphic processing unit, level set algorithm. Until now, the speed, bias, and precision of SegTool had not been validated. In a single stroke academic center, 2 vascular neurologists and 2 neuroradiologists independently performed a test-retest experiment that involved repeat measurements of static, unchanging intracerebral hemorrhage volumes on CT from 76 intracerebral hemorrhage cases. Measurements were made with SegTool and ABC/2. True intracerebral hemorrhage volumes were estimated from a consensus of repeat manual tracings by 2 operators. These data allowed us to estimate measurement bias, precision, and speed. The measurements with SegTool were not significantly different from the true intracerebral hemorrhage volumes, while ABC/2 overestimated volume by 45%. The interrater measurement variability with SegTool was 50% less than that with ABC/2. The average measurement times for ABC/2 and SegTool were 35.7 and 44.6 seconds, respectively. SegTool appears to have attributes superior to ABC/2 in terms of accuracy and interrater reliability with a 9-second delay in measurement time (on average); hence, it could be useful in clinical trials and practice. © 2017 by American Journal of Neuroradiology.

  19. A volume-equivalent spherical necrosis-tumor-normal liver model for estimating absorbed dose in yttrium-90 microsphere therapy.

    Science.gov (United States)

    Wu, Chin-Hui; Liao, Yi-Jen; Lin, Tzung-Yi; Chen, Yu-Cheng; Sun, Shung-Shung; Liu, Yen-Wan Hsueh; Hsu, Shih-Ming

    2016-11-01

    Primary hepatocellular carcinoma and metastatic liver tumors are highly malignant tumors in Asia. The incidence of fatal liver cancer is also increasing in the United States. The aim of this study was to establish a spherical tumor model and determine its accuracy in predicting the absorbed dose in yttrium-90 (Y-90) microsphere therapy for liver cancer. Liver morphology can be approximated by a spherical model comprising three concentric regions representing necrotic, tumor, and normal liver tissues. The volumes of these three regions represent those in the actual liver. A spherical tumor model was proposed to calculate the absorbed fractions in the spherical tumor, necrotic, and normal tissue regions. The THORplan treatment planning system and Monte Carlo N-particle extended codes were used for this spherical tumor model. Using the volume-equivalent method, a spherical tumor model was created to calculate the total absorbed fraction [under different tumor-to-healthy-liver ratios (TLRs)]. The patient-specific model (THORplan) results were used to verify the spherical tumor model results. The results for both the Y-90 spectrum and the Y-90 mean energy indicated that the absorbed fraction was a function of the tumor radius and mass. The absorbed fraction increased with tumor radius. The total absorbed fractions calculated using the spherical tumor model for necrotic, liver tumor, and normal liver tissues were in good agreement with the THORplan results, with differences of less than 3% for TLRs of 2-5. The results for the effect of TLR indicate that for the same tumor configuration, the total absorbed fraction decreased with increasing TLR; for the same shell tumor thickness and TLR, the total absorbed fraction was approximately constant; and for tumors with the same radius, the total fraction absorbed by the tumor increased with the shell thickness. The results from spherical tumor models with different tumor-to-healthy-liver ratios were highly consistent with the

  20. Review of models used for determining consequences of UF{sub 6} release: Development of model evaluation criteria. Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    Nair, S.K.; Chambers, D.B.; Park, S.H.; Hoffman, F.O. [Senes Oak Ridge, Inc., TN (United States). Center for Risk Analysis

    1997-11-01

    The objective of this study is to examine the usefulness and effectiveness of currently existing models that simulate the release of uranium hexafluoride from UF{sub 6}-handling facilities, subsequent reactions of UF{sub 6} with atmospheric moisture, and the dispersion of UF{sub 6} and reaction products in the atmosphere. The study evaluates screening-level and detailed public-domain models that were specifically developed for UF{sub 6} and models that were originally developed for the treatment of dense gases but are applicable to UF{sub 6} release, reaction, and dispersion. The model evaluation process is divided into three specific tasks: model-component evaluation; applicability evaluation; and user interface and quality assurance and quality control (QA/QC) evaluation. Within the model-component evaluation process, a model`s treatment of source term, thermodynamics, and atmospheric dispersion are considered and model predictions are compared with actual observations. Within the applicability evaluation process, a model`s applicability to Integrated Safety Analysis, Emergency Response Planning, and Post-Accident Analysis, and to site-specific considerations are assessed. Finally, within the user interface and QA/QC evaluation process, a model`s user-friendliness, presence and clarity of documentation, ease of use, etc. are assessed, along with its handling of QA/QC. This document presents the complete methodology used in the evaluation process.

  1. Energy Supply Planning Model documentation. Volume II. Technical manual. Final report

    Energy Technology Data Exchange (ETDEWEB)

    1981-09-01

    The Energy Supply Planning Model (ESPM) provides a systematic means of calculating, for any candidate energy development strategy, the total direct resources (capital, labor, materials, equipment, land, water, and energy) required to build and operate the energy-related supply facilities needed for the strategy. The model is used to analyze the feasibility and impacts of proposed strategies. This report provides a technical description of the model's computation methods and file structure to guide model set-up and allow program modification. It documents the model's primary data base. The ESPM consists of a number of separate programs which are generally run in sequence as submodels. Section 2 of this report provides an overview of these programs - their functions, application sequence, and the interconnecting file structure. The remaining sections describe each program and the model data base. The source code on the computer tape provides a complete definition of the algorithms used. (MCW)

  2. Performance of Leak Compensation in All-Age ICU Ventilators During Volume-Targeted Neonatal Ventilation: A Lung Model Study.

    Science.gov (United States)

    Itagaki, Taiga; Bennett, Desmond J; Chenelle, Christopher T; Fisher, Daniel F; Kacmarek, Robert M

    2017-01-01

    Volume-targeted ventilation is increasingly used in low birthweight infants because of the potential for reducing volutrauma and avoiding hypocapnea. However, it is not known what level of air leak is acceptable during neonatal volume-targeted ventilation when leak compensation is activated concurrently. Four ICU ventilators (Servo-i, PB980, V500, and Avea) were compared in available invasive volume-targeted ventilation modes (pressure control continuous spontaneous ventilation [PC-CSV] and pressure control continuous mandatory ventilation [PC-CMV]). The Servo-i and PB980 were tested with (+) and without (-) their proximal flow sensor. The V500 and Avea were tested with their proximal flow sensor as indicated by their manufacturers. An ASL 5000 lung model was used to simulate 4 neonatal scenarios (body weight 0.5, 1, 2, and 4 kg). The ASL 5000 was ventilated via an endotracheal tube with 3 different leaks. Two minutes of data were collected after each change in leak level, and the asynchrony index was calculated. Tidal volume (V T ) before and after the change in leak was assessed. The differences in delivered V T between before and after the change in leak were within ±5% in all scenarios with the PB980 (-/+) and V500. With the Servo-i (-/+), baseline V T was ≥10% greater than set V T during PC-CSV, and delivered V T markedly changed with leak. The Avea demonstrated persistent high V T in all leak scenarios. Across all ventilators, the median asynchrony index was 1% (interquartile range 0-27%) in PC-CSV and 1.8% (0-45%) in PC-CMV. The median asynchrony index was significantly higher in the Servo-i (-/+) than in the PB980 (-/+) and V500 in 1 and 2 kg scenarios during PC-CSV and PC-CMV. The PB980 and V500 were the only ventilators to acclimate to all leak scenarios and achieve targeted V T . Further clinical investigation is needed to validate the use of leak compensation during neonatal volume-targeted ventilation. Copyright © 2017 by Daedalus Enterprises.

  3. DTIC Review: Human, Social, Cultural and Behavior Modeling. Volume 9, Number 1 (CD-ROM)

    National Research Council Canada - National Science Library

    2008-01-01

    ...: Human, Social, Cultural and Behavior (HSCB) models are designed to help understand the structure, interconnections, dependencies, behavior, and trends associated with any collection of individuals...

  4. Predictor model for seasonal variations in skid resistance. Volume 2: Comprehensive report

    Science.gov (United States)

    Henry, J. J.; Saito, K.; Blackburn, R.

    1984-04-01

    Two models, utilizing data collected in 1979 and 1980, were developed to predict variations in skid resistance due to rainfall conditions, temperature effects, and time of the year. A generalized predictor model was developed from purely statistical considerations and a mechanistic model was developed from hypothesized mechanisms. This model may be utilized to estimate the skid resistance at any time in the season from a measurement made during the same season, or to adjust skid-resistance measurement made at any time during the season to the end-of-season level.

  5. A numerical model of two-phase flow at the micro-scale using the volume-of-fluid method

    Science.gov (United States)

    Shams, Mosayeb; Raeini, Ali Q.; Blunt, Martin J.; Bijeljic, Branko

    2018-03-01

    This study presents a simple and robust numerical scheme to model two-phase flow in porous media where capillary forces dominate over viscous effects. The volume-of-fluid method is employed to capture the fluid-fluid interface whose dynamics is explicitly described based on a finite volume discretization of the Navier-Stokes equations. Interfacial forces are calculated directly on reconstructed interface elements such that the total curvature is preserved. The computed interfacial forces are explicitly added to the Navier-Stokes equations using a sharp formulation which effectively eliminates spurious currents. The stability and accuracy of the implemented scheme is validated on several two- and three-dimensional test cases, which indicate the capability of the method to model two-phase flow processes at the micro-scale. In particular we show how the co-current flow of two viscous fluids leads to greatly enhanced flow conductance for the wetting phase in corners of the pore space, compared to a case where the non-wetting phase is an inviscid gas.

  6. Using snowflake surface-area-to-volume ratio to model and interpret snowfall triple-frequency radar signatures

    Directory of Open Access Journals (Sweden)

    M. Gergely

    2017-10-01

    Full Text Available The snowflake microstructure determines the microwave scattering properties of individual snowflakes and has a strong impact on snowfall radar signatures. In this study, individual snowflakes are represented by collections of randomly distributed ice spheres where the size and number of the constituent ice spheres are specified by the snowflake mass and surface-area-to-volume ratio (SAV and the bounding volume of each ice sphere collection is given by the snowflake maximum dimension. Radar backscatter cross sections for the ice sphere collections are calculated at X-, Ku-, Ka-, and W-band frequencies and then used to model triple-frequency radar signatures for exponential snowflake size distributions (SSDs. Additionally, snowflake complexity values obtained from high-resolution multi-view snowflake images are used as an indicator of snowflake SAV to derive snowfall triple-frequency radar signatures. The modeled snowfall triple-frequency radar signatures cover a wide range of triple-frequency signatures that were previously determined from radar reflectivity measurements and illustrate characteristic differences related to snow type, quantified through snowflake SAV, and snowflake size. The results show high sensitivity to snowflake SAV and SSD maximum size but are generally less affected by uncertainties in the parameterization of snowflake mass, indicating the importance of snowflake SAV for the interpretation of snowfall triple-frequency radar signatures.

  7. Validity of Four-Compartment Model Body Fat In Physically Active Men And Women When Using DXA For Body Volume.

    Science.gov (United States)

    Nickerson, Brett S; Esco, Michael R; Bishop, Phillip A; Kliszczewicz, Brian M; Park, Kyung-Shin; Williford, Henry N

    2017-12-01

    The purpose of this study was twofold: 1) compare body volume (BV) estimated from dual energy X-ray absorptiometry (DXA) to BV from a criterion underwater weighing (UWW) with simultaneous residual lung volume (RLV), and 2) compare four-compartment (4C) model body fat percentage (BF%) values when deriving BV via DXA (4C DXA ) and UWW (4C UWW ) in physically active men and women. One hundred twenty-two adults (62 men and 60 women) who self-reported physical activity levels of at least 1,000 MET·min·wk -1 volunteered to participate (age = 22 ± 5 years). DXA BV was determined with the recent equation from Smith-Ryan et al. while criterion BV was determined from UWW with simultaneous RLV. The mean BV values for DXA were not significant compared with UWW in women (p = .80; constant error [CE] = 0.0L), but were significantly higher in the entire sample and men (both p women (p = .56; CE = -0.3%), but were significantly higher in the entire sample and men (both p men and women. However, due to the SEEs and 95% LOAs, the current study recommends using UWW with simultaneous RLV for BV in a criterion 4C model when high individual accuracy is desired.

  8. A three-dimensional model for quantification of the representative elementary volume of tortuosity in granular porous media

    Science.gov (United States)

    Wu, Ming; Wu, Jianfeng; Wu, Jichun; Hu, Bill X.

    2018-02-01

    For most of aquifers with abundant groundwater resource, quantifications of tortuosity and corresponding representative elementary volume (REV) are very essential to improve the understanding of groundwater and contaminant transfers in porous media. In this study, a mathematical model of tortuosity based on the three dimensional (3D) microstructure of regular tetrahedron (RTM) is proposed to quantify tortuosity and corresponding REV of granular porous media. The calculated tortuosity using the new 3D RTM model agrees well with the measured tortuosity in experiment, indicating that the new 3D microstructure model is more appropriate to precisely delineate the tortuosity of granular porous media. Afterward, the new model is utilized to quantify the tortuosity of heterogeneous translucent silica. Moreover, corresponding REV is estimated using a criterion of relative gradient error (εgi). Results suggest minimum τ-REV sizes most distribute in 0.0-5.0 mm and the bound of cumulative frequency above 80% is larger than 3.00 mm. The REV scale of tortuosity has its own rationality and superiority over that estimated by two-dimensional (2D) tortuosity model, implying the proposed 3D tortuosity model of RTM is helpful for understanding the tortuosity of flow paths in granular porous media and corresponding REV estimation of tortuosity.

  9. Development of a dynamic model to evaluate economic recovery following a nuclear attack. Volume 1. Description and simulations. Final report

    International Nuclear Information System (INIS)

    Peterson, D.W.; Silverman, W.S.; Weil, H.B.; Willard, S.

    1980-11-01

    A highly-robust, dynamic simulation model of the US economy has been constructed to evaluate the likely economic response after various nuclear attacks or other severe disruptions, under various policies and assumptions. The model consists of a large system of nonlinear, recursive, time-difference equations. The solution-interval of the model is adjustable, with a maximum value of three weeks. The model represents the economy in thirteen sectors. Each sector contains a detailed representation of production, distribution, supply constraints, finance, employment, pricing, and wages. Also included are a full input-output representation of the interconnections among the sectors, and the psychological responses of corporate planners, consumers, and the labor force. The model's equations are formulated to remain consistent and realistic for all values of the variables, including the most extreme conditions. Therefore, the model can realistically simulate any degree or time sequence of nuclear attacks, pre-attack surges, mobilization, or policy shifts. Simulation experiments with the model suggest that the economy is highly vulnerable to nuclear attack, and that recovery requires extensive preparation, including psychological readiness, technology maintenance, special financial policies, and (if possible) maintenance of foreign trade. Civil defense policies must be adaptive (contingent on the nature of the damage) and must strive for balance among sectors, rather than maximum survival. This volume includes two appendices. Appendix A defines the aggregation of the model. Appendix B outlines the range of attack scenarios, pre-attack civil defense policies, and post-attack civil defense policies that can be evaluated with the model, including the model variables applicable to implementing those policies

  10. Generation of predictive price and trading volume patterns in a model of dynamically evolving free market supply and demand

    Directory of Open Access Journals (Sweden)

    J. K. Wang

    2001-01-01

    Full Text Available I present a model of stock market price fluctuations incorporating effects of share supply as a history-dependent function of previous purchases and share demand as a function of price deviation from moving averages. Price charts generated show intervals of oscillations switching amplitude and frequency suddenly in time, forming price and trading volume patterns well-known in market technical analysis. Ultimate price trends agree with traditional predictions for specific patterns. The consideration of dynamically evolving supply and demand in this model resolves the apparent contradiction with the Efficient Market Hypothesis: perceptions of imprecise equity values by a world of investors evolve over non-negligible periods of time, with dependence on price history.

  11. Finite Volume schemes on unstructured grids for non-local models: Application to the simulation of heat transport in plasmas

    Energy Technology Data Exchange (ETDEWEB)

    Goudon, Thierry, E-mail: thierry.goudon@inria.fr [Team COFFEE, INRIA Sophia Antipolis Mediterranee (France); Labo. J.A. Dieudonne CNRS and Univ. Nice-Sophia Antipolis (UMR 7351), Parc Valrose, 06108 Nice cedex 02 (France); Parisot, Martin, E-mail: martin.parisot@gmail.com [Project-Team SIMPAF, INRIA Lille Nord Europe, Park Plazza, 40 avenue Halley, F-59650 Villeneuve d' Ascq cedex (France)

    2012-10-15

    In the so-called Spitzer-Haerm regime, equations of plasma physics reduce to a nonlinear parabolic equation for the electronic temperature. Coming back to the derivation of this limiting equation through hydrodynamic regime arguments, one is led to construct a hierarchy of models where the heat fluxes are defined through a non-local relation which can be reinterpreted as well by introducing coupled diffusion equations. We address the question of designing numerical methods to simulate these equations. The basic requirement for the scheme is to be asymptotically consistent with the Spitzer-Haerm regime. Furthermore, the constraints of physically realistic simulations make the use of unstructured meshes unavoidable. We develop a Finite Volume scheme, based on Vertex-Based discretization, which reaches these objectives. We discuss on numerical grounds the efficiency of the method, and the ability of the generalized models in capturing relevant phenomena missed by the asymptotic problem.

  12. Theory versus experiment for the rotordynamic coefficients of labyrinth gas seals. I - A two control volume model

    Science.gov (United States)

    Scharrer, J. K.

    1987-01-01

    The basic equations are derived for a two-control-volume model for compressible flow in a labyrinth seal. The recirculation velocity in the cavity is incorporated into the model for the first time. The flow is assumed to be completely turbulent and isoenergetic. The wall friction factors are determined using the Blasius formula. Jet flow theory is used for the calculation of the recirculation velocity in the cavity. Linearized zeroth- and first-order perturbation equations are developed for small motion about a centered position by an expansion in the eccentricity ratio. The zeroth-order pressure distribution is found by satisfying the leakage equation while the circumferential velocity distribution is determined by satisfying the momentum equations. The first-order equations are solved by a separation of variable solution. Integration of the resultant pressure distribution along and around the seal defines the reaction force developed by the seal and the corresponding dynamic coefficients.

  13. THE HYDROCARBON SPILL SCREENING MODEL (HSSM), VOLUME 2: THEORETICAL BACKGROUND AND SOURCE CODES

    Science.gov (United States)

    A screening model for subsurface release of a nonaqueous phase liquid which is less dense than water (LNAPL) is presented. The model conceptualizes the release as consisting of 1) vertical transport from near the surface to the capillary fringe, 2) radial spreading of an LNAPL l...

  14. Mathematical models from the collections of universities and museums : photograph volume and commentary

    CERN Document Server

    2017-01-01

    This book presents beautiful photos of mathematical models of geometric surfaces made from a variety of materials including plaster, metal, paper, wood, and string. The construction of these models at the time (of Felix Klein and others) was not an end in itself, but was accompanied by mathematical research especially in the field of algebraic geometry. The models were used to illustrate the mathematical objects defined by abstract formulas, either as equations or parameterizations. In the second part of the book, the models are explained by experts in the field of geometry. This book is a reprint thirty years after the original publication in 1986 with a new preface by Gert-Martin Greuel. The models have a timeless appeal and a historical value. The Editor Prof. Dr. Gerd Fischer, Department of Mathematics, Technical University of Munich.

  15. Verification and transfer of thermal pollution model. Volume 4: User's manual for three-dimensional rigid-lid model

    Science.gov (United States)

    Lee, S. S.; Nwadike, E. V.; Sinha, S. E.

    1982-01-01

    The theory of a three dimensional (3-D) mathematical thermal discharge model and a related one dimensional (1-D) model are described. Model verification at two sites, a separate user's manual for each model are included. The 3-D model has two forms: free surface and rigid lid. The former allows a free air/water interface and is suited for significant surface wave heights compared to mean water depth, estuaries and coastal regions. The latter is suited for small surface wave heights compared to depth because surface elevation was removed as a parameter. These models allow computation of time dependent velocity and temperature fields for given initial conditions and time-varying boundary conditions. The free surface model also provides surface height variations with time.

  16. Low level waste management: a compilation of models and monitoring techniques. Volume 1

    International Nuclear Information System (INIS)

    Mosier, J.E.; Fowler, J.R.; Barton, C.J.

    1980-04-01

    In support of the National Low-Level Waste (LLW) Management Research and Development Program being carried out at Oak Ridge National Laboratory, Science Applications, Inc., conducted a survey of models and monitoring techniques associated with the transport of radionuclides and other chemical species from LLW burial sites. As a result of this survey, approximately 350 models were identified. For each model the purpose and a brief description are presented. To the extent possible, a point of contact and reference material are identified. The models are organized into six technical categories: atmospheric transport, dosimetry, food chain, groundwater transport, soil transport, and surface water transport. About 4% of the models identified covered other aspects of LLW management and are placed in a miscellaneous category. A preliminary assessment of all these models was performed to determine their ability to analyze the transport of other chemical species. The models that appeared to be applicable are identified. A brief survey of the state-of-the-art techniques employed to monitor LLW burial sites is also presented, along with a very brief discussion of up-to-date burial techniques

  17. Low level waste management: a compilation of models and monitoring techniques. Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    Mosier, J.E.; Fowler, J.R.; Barton, C.J. (comps.)

    1980-04-01

    In support of the National Low-Level Waste (LLW) Management Research and Development Program being carried out at Oak Ridge National Laboratory, Science Applications, Inc., conducted a survey of models and monitoring techniques associated with the transport of radionuclides and other chemical species from LLW burial sites. As a result of this survey, approximately 350 models were identified. For each model the purpose and a brief description are presented. To the extent possible, a point of contact and reference material are identified. The models are organized into six technical categories: atmospheric transport, dosimetry, food chain, groundwater transport, soil transport, and surface water transport. About 4% of the models identified covered other aspects of LLW management and are placed in a miscellaneous category. A preliminary assessment of all these models was performed to determine their ability to analyze the transport of other chemical species. The models that appeared to be applicable are identified. A brief survey of the state-of-the-art techniques employed to monitor LLW burial sites is also presented, along with a very brief discussion of up-to-date burial techniques.

  18. Review of models used for determining consequences of UF6 release: Development of model evaluation criteria. Volume 1

    International Nuclear Information System (INIS)

    Nair, S.K.; Chambers, D.B.; Park, S.H.; Hoffman, F.O.

    1997-11-01

    The objective of this study is to examine the usefulness and effectiveness of currently existing models that simulate the release of uranium hexafluoride from UF 6 -handling facilities, subsequent reactions of UF 6 with atmospheric moisture, and the dispersion of UF 6 and reaction products in the atmosphere. The study evaluates screening-level and detailed public-domain models that were specifically developed for UF 6 and models that were originally developed for the treatment of dense gases but are applicable to UF 6 release, reaction, and dispersion. The model evaluation process is divided into three specific tasks: model-component evaluation; applicability evaluation; and user interface and quality assurance and quality control (QA/QC) evaluation. Within the model-component evaluation process, a model's treatment of source term, thermodynamics, and atmospheric dispersion are considered and model predictions are compared with actual observations. Within the applicability evaluation process, a model's applicability to Integrated Safety Analysis, Emergency Response Planning, and Post-Accident Analysis, and to site-specific considerations are assessed. Finally, within the user interface and QA/QC evaluation process, a model's user-friendliness, presence and clarity of documentation, ease of use, etc. are assessed, along with its handling of QA/QC. This document presents the complete methodology used in the evaluation process

  19. Review of models used for determining consequences of UF{sub 6} release: Model evaluation report. Volume 2

    Energy Technology Data Exchange (ETDEWEB)

    Nair, S.K.; Chambers, D.B.; Park, S.H.; Radonjic, Z.R.; Coutts, P.T.; Lewis, C.J.; Hammonds, J.S.; Hoffman, F.O. [Senes Oak Ridge, Inc., TN (United States). Center for Risk Analysis

    1997-11-01

    Three uranium hexafluoride-(UF{sub 6}-) specific models--HGSYSTEM/UF{sub 6}, Science Application International Corporation, and RTM-96; three dense-gas models--DEGADIS, SLAB, and the Chlorine Institute methodology; and one toxic chemical model--AFTOX--are evaluated on their capabilities to simulate the chemical reactions, thermodynamics, and atmospheric dispersion of UF{sub 6} released from accidents at nuclear fuel-cycle facilities, to support Integrated Safety Analysis, Emergency Response Planning, and Post-Accident Analysis. These models are also evaluated for user-friendliness and for quality assurance and quality control features, to ensure the validity and credibility of the results. Model performance evaluations are conducted for the three UF{sub 6}-specific models, using field data on releases of UF{sub 6} and other heavy gases. Predictions from the HGSYSTEM/UF{sub 6} and SAIC models are within an order of magnitude of the field data, but the SAIC model overpredicts beyond an order of magnitude for a few UF{sub 6}-specific data points. The RTM-96 model provides overpredictions within a factor of 3 for all data points beyond 400 m from the source. For one data set, however, the RTM-96 model severely underpredicts the observations within 200 m of the source. Outputs of the models are most sensitive to the meteorological parameters at large distances from the source and to certain source-specific and meteorological parameters at distances close to the source. Specific recommendations are being made to improve the applicability and usefulness of the three models and to choose a specific model to support the intended analyses. Guidance is also provided on the choice of input parameters for initial dilution, building wake effects, and distance to completion of UF{sub 6} reaction with water.

  20. RF model of the distribution system as a communication channel, phase 2. Volume 1: Summary Report

    Science.gov (United States)

    Rustay, R. C.; Gajjar, J. T.; Rankin, R. W.; Wentz, R. C.; Wooding, R.

    1982-01-01

    The design, implementation, and verification of a computerized model for predicting the steady-state sinusoidal response of radial (tree) configured distribution feeders was undertaken. That work demonstrated the feasibility and validity based on verification measurements made on a limited size portion of an actual live feeder. On that basis a follow-on effort concerned with (1) extending the verification based on a greater variety of situations and network size, (2) extending the model capabilities for reverse direction propagation, (3) investigating parameter sensitivities, (4) improving transformer models, and (5) investigating procedures/fixes for ameliorating propagation trouble spots was conducted. Results are summarized.

  1. Models for Ballistic Wind Measurement Error Analysis. Volume II. Users’ Manual.

    Science.gov (United States)

    1983-01-01

    TEST CHART NATIONAL li ’A il (If IANP) ARDl A -CR-83-0008-1 Reports Control Symbol OSO - 1366 MODELS FOR BALLISTIC WIND MEASUREMENTERROR ANALYSIS...AD-A129 360 MODELS FOR BALLSTIC WIND MEASUREMENT ERROR ANALYSIS VO UME 11USERS’ MAN..U) NEW REXICO STATE UNIV LAS U SS CRUCES PHYSICAL SCIENCE LAR...ACCESSION NO. 3. RECIPIENT’S CATALOG NUMBER SASL-CR-83-0008-1 4. TITLE (and Subtitle) 5 TYPE OF REPORT & PERIOD COVERED MODELS FOR BALLISTIC WIND

  2. Energy-supply planning-model documentation. Volume 1: User manual

    Science.gov (United States)

    1981-09-01

    The model modified to address issues of importance to energy planning for developing countries and has been adapted for use in studies for Egypt, Indonesia, Peru, Portugal and South Korea. Computer programs were developed to assist in the adaptation process. The characteristics of the ESPM model are given. The information required to make ESPM applications once the model has been made operational on a computer system is provided. An overview of all the ESPM subprograms, including descriptions of the functions and application of each subprogram is provided. Data input forms, a detailed description of each input, and sample run decks and reports for each subprogram are included.

  3. A finite volume alternate direction implicit approach to modeling selective laser melting

    DEFF Research Database (Denmark)

    Hattel, Jesper Henri; Mohanty, Sankhya

    2013-01-01

    Over the last decade, several studies have attempted to develop thermal models for analyzing the selective laser melting process with a vision to predict thermal stresses, microstructures and resulting mechanical properties of manufactured products. While a holistic model addressing all involved...... is proposed for modeling single-layer and few-layers selective laser melting processes. The ADI technique is implemented and applied for two cases involving constant material properties and non-linear material behavior. The ADI FV method consume less time while having comparable accuracy with respect to 3D...

  4. Space shuttle phase B wind tunnel model and test information. Volume 3: Launch configuration

    Science.gov (United States)

    Glynn, J. L.; Poucher, D. E.

    1988-01-01

    Archived wind tunnel test data are available for flyback booster or other alternate recoverable configuration as well as reusable orbiters studied during initial development (Phase B) of the Space Shuttle, including contractor data for an extensive variety of configurations with an array of wing and body planforms. The test data have been compiled into a database and are available for application to current winged flyback or recoverable booster aerodynamic studies. The Space Shuttle Phase B Wind Tunnel Database is structured by vehicle component and configuration. Basic components include booster, orbiter, and launch vehicle. Booster configuration types include straight and delta wings, canard, cylindrical, retroglide and twin body. Orbiter configurations include straight and delta wings, lifting body, drop tanks and double delta wings. Launch configurations include booster and orbiter components in various stacked and tandem combinations. The digital database consists of 220 files containing basic tunnel data. Database structure is documented in a series of reports which include configuration sketches for the various planforms tested. This is Volume 3 -- launch configurations.

  5. Computational methods and modeling. 1. Sampling a Position Uniformly in a Trilinear Hexahedral Volume

    International Nuclear Information System (INIS)

    Urbatsch, Todd J.; Evans, Thomas M.; Hughes, H. Grady

    2001-01-01

    Monte Carlo particle transport plays an important role in some multi-physics simulations. These simulations, which may additionally involve deterministic calculations, typically use a hexahedral or tetrahedral mesh. Trilinear hexahedrons are attractive for physics calculations because faces between cells are uniquely defined, distance-to-boundary calculations are deterministic, and hexahedral meshes tend to require fewer cells than tetrahedral meshes. We discuss one aspect of Monte Carlo transport: sampling a position in a tri-linear hexahedron, which is made up of eight control points, or nodes, and six bilinear faces, where each face is defined by four non-coplanar nodes in three-dimensional Cartesian space. We derive, code, and verify the exact sampling method and propose an approximation to it. Our proposed approximate method uses about one-third the memory and can be twice as fast as the exact sampling method, but we find that its inaccuracy limits its use to well-behaved hexahedrons. Daunted by the expense of the exact method, we propose an alternate approximate sampling method. First, calculate beforehand an approximate volume for each corner of the hexahedron by taking one-eighth of the volume of an imaginary parallelepiped defined by the corner node and the three nodes to which it is directly connected. For the sampling, assume separability in the parameters, and sample each parameter, in turn, from a linear pdf defined by the sum of the four corner volumes at each limit (-1 and 1) of the parameter. This method ignores the quadratic portion of the pdf, but it requires less storage, has simpler sampling, and needs no extra, on-the-fly calculations. We simplify verification by designing tests that consist of one or more cells that entirely fill a unit cube. Uniformly sampling complicated cells that fill a unit cube will result in uniformly sampling the unit cube. Unit cubes are easily analyzed. The first problem has four wedges (or tents, or A frames) whose

  6. High Resolution 3-D Finite-Volume Coastal Ocean Modeling in Lower Campbell River and Discovery Passage, British Columbia, Canada

    Directory of Open Access Journals (Sweden)

    Yuehua Lin

    2014-03-01

    Full Text Available The 3-D unstructured-grid, Finite-Volume Coastal Ocean Model (FVCOM was used to simulate the flows in Discovery Passage including the adjoining Lower Campbell River, British Columbia, Canada. Challenges in the studies include the strong tidal currents (e.g., up to 7.8 m/s in Seymour Narrows and tailrace discharges, small-scale topographic features and steep bottom slopes, and stratification affected by the Campbell River freshwater discharges. Two applications of high resolution 3-D FVCOM modeling were conducted. One is for the Lower Campbell River extending upstream as far as the John Hart Hydroelectric dam. The horizontal resolution varies from 0.27 m to 32 m in the unstructured triangular mesh to resolve the tailrace flow. The bottom elevation decreases ~14 m within the distance of ~1.4 km along the river. This pioneering FVCOM river modeling demonstrated a very good performance in simulating the river flow structures. The second application is to compute ocean currents immediately above the seabed along the present underwater electrical cable crossing routes across Discovery Passage. Higher resolution was used near the bottom with inter-layer spacing ranging from 0.125 to 0.0005 of total water depth. The model behaves very well in simulating the strong tidal currents in the area at high resolution in both the horizontal and vertical. One year maximum near bottom tidal current along the routes was then analyzed using the model results.

  7. Cellular Automata Modelling of Dynamics of Volumes of Sales of a Trade Company

    OpenAIRE

    Zhikharevich Vladimir V.; Matsyuk Nataliya A.

    2013-01-01

    The article substantiates expediency of use of the multi-agent simulation modelling in the study of dynamics of complex economic systems. It shows a possibility to use cellular automata in construction of simulation economic models, particularly models of consumers’ behaviour, in principle. It describes a simulation model, which could be sophisticated further for deeper analysis of a studied phenomenon.В статье обоснована целесообразность использования многоагентного имитационного моделирован...

  8. Resource Allocation Model for Great Plains Regional Medical Command: Volume 1

    National Research Council Canada - National Science Library

    Wojcik, Barbara E; Humphrey, Rebecca J; Oakley, Carolyn L; Morrison, Scott C; Devore , Jr., Raymond B; Hassell, Harrison L

    2005-01-01

    ... relationship to treatment facility, beneficiary category, patient's age, and gender. The components of the model are based on patient-level data and use historical data for fiscal years 2001, 2002, and 2003...

  9. Traffic analysis toolbox volume XI : weather and traffic analysis, modeling and simulation.

    Science.gov (United States)

    2010-12-01

    This document presents a weather module for the traffic analysis tools program. It provides traffic engineers, transportation modelers and decisions makers with a guide that can incorporate weather impacts into transportation system analysis and mode...

  10. RF model of the distribution system as a communication channel, phase 2. Volume 3: Appendices

    Science.gov (United States)

    Rustay, R. C.; Gajjar, J. T.; Rankin, R. W.; Wentz, R. C.; Wooding, R.

    1982-01-01

    Program documentation concerning the design, implementation, and verification of a computerized model for predicting the steady-state sinusoidal response of radial configured distribution feeders is presented in these appendices.

  11. Integrated Hydrogeological Model of the General Separations Area. Volume 1: hydrogeologic framework

    Energy Technology Data Exchange (ETDEWEB)

    Harris, M.K. [Westinghouse Savannah River Company, AIKEN, SC (United States); Smits, A.D.; Hawkins, K.L.; Flach, G.P.

    1997-08-01

    This report models the Gordon aquifer, the Gordon confining unit, and the `lower` aquifer zone, `tan clay` confining zone, and `upper` aquifer zone of the Water Table aquifer. The report presents structure-contour and isopach maps of each unit.

  12. A simulation model for wind energy storage systems. Volume 3: Program descriptions

    Science.gov (United States)

    Warren, A. W.; Edsinger, R. W.; Burroughs, J. D.

    1977-01-01

    Program descriptions, flow charts, and program listings for the SIMWEST model generation program, the simulation program, the file maintenance program, and the printer plotter program are given. For Vol 2, see .

  13. Industrial Sector Technology Use Model (ISTUM): industrial energy use in the United States, 1974-2000. Volume 3. Appendix on service and fuel demands. Final report

    Energy Technology Data Exchange (ETDEWEB)

    1979-10-01

    This book is the third volume of the ISTUM report. The first volume of the report describes the primary model logic and the model's data inputs. The second volume lists and evaluates the results of one model run. This and the fourth volume give supplementary information in two sets of model data - the energy consumption base and technology descriptions. Chapter III of Vol. I, Book 1 describes the ISTUM demand base and explains how that demand base was developed. This volume serves as a set of appendices to that chapter. The chapter on demands in Vol. I describes the assumptions and methodology used in constructing the ISTUM demand base; this volume simply lists tables of data from that demand base. This book divides the demand tables into two appendices. Appendix III-1 contains detailed tables on ISTUM fuel-consumption estimates, service-demand forecasts, and size and load-factor distributions. Appendix III-2 contains tables detailing ISTUM allocations of each industry's fuel consumption to service sectors. The tables show how the ECDB was used to develop the ISTUM demand base.

  14. Carbon emissions, logistics volume and GDP in China: empirical analysis based on panel data model.

    Science.gov (United States)

    Guo, Xiaopeng; Ren, Dongfang; Shi, Jiaxing

    2016-12-01

    This paper studies the relationship among carbon emissions, GDP, and logistics by using a panel data model and a combination of statistics and econometrics theory. The model is based on the historical data of 10 typical provinces and cities in China during 2005-2014. The model in this paper adds the variability of logistics on the basis of previous studies, and this variable is replaced by the freight turnover of the provinces. Carbon emissions are calculated by using the annual consumption of coal, oil, and natural gas. GDP is the gross domestic product. The results showed that the amount of logistics and GDP have a contribution to carbon emissions and the long-term relationships are different between different cities in China, mainly influenced by the difference among development mode, economic structure, and level of logistic development. After the testing of panel model setting, this paper established a variable coefficient model of the panel. The influence of GDP and logistics on carbon emissions is obtained according to the influence factors among the variables. The paper concludes with main findings and provides recommendations toward rational planning of urban sustainable development and environmental protection for China.

  15. Monte-Carlo model development for evaluation of current clinical target volume definition for heterogeneous and hypoxic glioblastoma.

    Science.gov (United States)

    Moghaddasi, L; Bezak, E; Harriss-Phillips, W

    2016-05-07

    Clinical target volume (CTV) determination may be complex and subjective. In this work a microscopic-scale tumour model was developed to evaluate current CTV practices in glioblastoma multiforme (GBM) external radiotherapy. Previously, a Geant4 cell-based dosimetry model was developed to calculate the dose deposited in individual GBM cells. Microscopic extension probability (MEP) models were then developed using Matlab-2012a. The results of the cell-based dosimetry model and MEP models were combined to calculate survival fractions (SF) for CTV margins of 2.0 and 2.5 cm. In the current work, oxygenation and heterogeneous radiosensitivity profiles were incorporated into the GBM model. The genetic heterogeneity was modelled using a range of α/β values (linear-quadratic model parameters) associated with different GBM cell lines. These values were distributed among the cells randomly, taken from a Gaussian-weighted sample of α/β values. Cellular oxygen pressure was distributed randomly taken from a sample weighted to profiles obtained from literature. Three types of GBM models were analysed: homogeneous-normoxic, heterogeneous-normoxic, and heterogeneous-hypoxic. The SF in different regions of the tumour model and the effect of the CTV margin extension from 2.0-2.5 cm on SFs were investigated for three MEP models. The SF within the beam was increased by up to three and two orders of magnitude following incorporation of heterogeneous radiosensitivities and hypoxia, respectively, in the GBM model. However, the total SF was shown to be overdominated by the presence of tumour cells in the penumbra region and to a lesser extent by genetic heterogeneity and hypoxia. CTV extension by 0.5 cm reduced the SF by a maximum of 78.6  ±  3.3%, 78.5  ±  3.3%, and 77.7  ±  3.1% for homogeneous and heterogeneous-normoxic, and heterogeneous hypoxic GBMs, respectively. Monte-Carlo model was developed to quantitatively evaluate SF for genetically

  16. Sparing Healthy Tissue and Increasing Tumor Dose Using Bayesian Modeling of Geometric Uncertainties for Planning Target Volume Personalization

    Energy Technology Data Exchange (ETDEWEB)

    Herschtal, Alan, E-mail: Alan.Herschtal@petermac.org [Department of Biostatistics and Clinical Trials, Peter MacCallum Cancer Centre, Melbourne (Australia); Faculty of Health, Arts and Design, Swinburne University of Technology, Melbourne (Australia); Te Marvelde, Luc [Department of Biostatistics and Clinical Trials, Peter MacCallum Cancer Centre, Melbourne (Australia); Mengersen, Kerrie [School of Mathematical Sciences, Science and Engineering Faculty, Queensland University of Technology, Brisbane (Australia); Foroudi, Farshad [Department of Radiation Oncology, Peter MacCallum Cancer Centre, Melbourne (Australia); The Sir Peter MacCallum Department of Oncology, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne (Australia); Eade, Thomas [Northern Sydney Cancer Centre, Radiation Oncology Department, Royal North Shore Hospital, St. Leonards, Sydney (Australia); Northern Clinical School, University of Sydney (Australia); Pham, Daniel [Department of Radiation Therapy, Peter MacCallum Cancer Centre, Melbourne (Australia); Caine, Hannah [Northern Sydney Cancer Centre, Radiation Oncology Department, Royal North Shore Hospital, St. Leonards, Sydney (Australia); Kron, Tomas [The Sir Peter MacCallum Department of Oncology, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne (Australia); Department of Physical Sciences, Peter MacCallum Cancer Centre, Melbourne (Australia)

    2015-06-01

    Objective: To develop a mathematical tool that can update a patient's planning target volume (PTV) partway through a course of radiation therapy to more precisely target the tumor for the remainder of treatment and reduce dose to surrounding healthy tissue. Methods and Materials: Daily on-board imaging was used to collect large datasets of displacements for patients undergoing external beam radiation therapy for solid tumors. Bayesian statistical modeling of these geometric uncertainties was used to optimally trade off between displacement data collected from previously treated patients and the progressively accumulating data from a patient currently partway through treatment, to optimally predict future displacements for that patient. These predictions were used to update the PTV position and margin width for the remainder of treatment, such that the clinical target volume (CTV) was more precisely targeted. Results: Software simulation of dose to CTV and normal tissue for 2 real prostate displacement datasets consisting of 146 and 290 patients treated with a minimum of 30 fractions each showed that re-evaluating the PTV position and margin width after 8 treatment fractions reduced healthy tissue dose by 19% and 17%, respectively, while maintaining CTV dose. Conclusion: Incorporating patient-specific displacement patterns from early in a course of treatment allows PTV adaptation for the remainder of treatment. This substantially reduces the dose to healthy tissues and thus can reduce radiation therapy–induced toxicities, improving patient outcomes.

  17. A fractional transient model for the viscoplastic response of polymers based on a micro-mechanism of free volume distribution

    Science.gov (United States)

    Spathis, G.; Kontou, E.

    2017-11-01

    In the present work, the nonlinear viscoelastic/viscoplastic response of polymeric materials is described by introducing essential modifications on a model developed in previous works. A constitutive equation of viscoelasticity, based on the transient network theory, is introduced in a more generalized form, which takes into account volume changes during deformation. This time-dependent equation accounts for the nonlinearity and viscoplasticity at small elastic and finite plastic strain regime. The present description was proved to be more flexible, given that it contains a relaxation function that has been derived by considering instead of first order kinetics a fractional derivative that controls the rate of molecular chain detachment from their junctions. Therefore, the new equation has a more global character, appropriate for cases where heavy tails are expected. On the basis of the distributed nature of free volume, a new functional form of the rate of plastic deformation is developed, which is combined with a proper kinematic formulation and leads to the separation of the total strain into the elastic and plastic part. A three-dimensional constitutive equation is then derived for an isotropic, compressible medium. This analysis was proved to be capable of capturing the main aspects of inelastic response as well as the instability stage taking place at the tertiary creep, related to the creep failure.

  18. Modeling mass balance and volume of Xiao Dongkemadi glacier in the Central Tibetan Plateau from 1989 to 2050

    Science.gov (United States)

    Duan, K.

    2015-12-01

    The Tibetan Plateau (TP) holds ten thousands of alpine glaciers in mid-latitude, which have shrunk with an accelerating retreat rate recently. Here, we applied a temperature-index distributed mass-balance model coupled with a volume-area scaling method to Xiao Dongkemadi Glacier (XDG) in the central TP, to assess its response to climate change. The result shows the simulated mass balance is in a good agreement with observations (R2=0.75, pRegCM4 under the climate scenarios RCP4.5 and RCP8.5 from 2013 to 2050. The simulated terminus elevation of the glacier will rise from 5454m a.s.l. in 2013 to 5533m a.s.l. (RCP4.5) and 5543m a.s.l (RCP8.5) in 2050. XDG will lose its volume with an increasing rate of 600-700m3 a-1 during the period of 1989-2050, indicating the melting water will enhance the river runoff. But for the long term, the contribution to the river runoff will decrease for shrinkage of glacier scale.

  19. International Space Station Human Behavior and Performance Competency Model: Volume II

    Science.gov (United States)

    Schmidt, Lacey

    2008-01-01

    This document further defines the behavioral markers identified in the document "Human Behavior and Performance Competency Model" Vol. I. The Human Behavior and Performance (HBP) competencies were recommended as requirements to participate in international long duration missions, and form the basis for determining the HBP training curriculum for long duration crewmembers. This document provides details, examples, knowledge areas, and affective skills to support the use of the HBP competencies in training and evaluation. This document lists examples and details specific to HBP competencies required of astronauts/cosmonauts who participate in ISS expedition and other international long-duration missions. Please note that this model does not encompass all competencies required. While technical competencies are critical for crewmembers, they are beyond the scope of this document. Additionally, the competencies in this model (and subsequent objectives) are not intended to limit the internal activities or training programs of any international partner.

  20. A simulation model for wind energy storage systems. Volume 1: Technical report

    Science.gov (United States)

    Warren, A. W.; Edsinger, R. W.; Chan, Y. K.

    1977-01-01

    A comprehensive computer program for the modeling of wind energy and storage systems utilizing any combination of five types of storage (pumped hydro, battery, thermal, flywheel and pneumatic) was developed. The level of detail of Simulation Model for Wind Energy Storage (SIMWEST) is consistent with a role of evaluating the economic feasibility as well as the general performance of wind energy systems. The software package consists of two basic programs and a library of system, environmental, and load components. The first program is a precompiler which generates computer models (in FORTRAN) of complex wind source storage application systems, from user specifications using the respective library components. The second program provides the techno-economic system analysis with the respective I/O, the integration of systems dynamics, and the iteration for conveyance of variables. SIMWEST program, as described, runs on the UNIVAC 1100 series computers.

  1. Tornado missile simulation and design methodology. Volume 2: model verification and data base updates. Final report

    International Nuclear Information System (INIS)

    Twisdale, L.A.; Dunn, W.L.

    1981-08-01

    A probabilistic methodology has been developed to predict the probabilities of tornado-propelled missiles impacting and damaging nuclear power plant structures. Mathematical models of each event in the tornado missile hazard have been developed and sequenced to form an integrated, time-history simulation methodology. The models are data based where feasible. The data include documented records of tornado occurrence, field observations of missile transport, results of wind tunnel experiments, and missile impact tests. Probabilistic Monte Carlo techniques are used to estimate the risk probabilities. The methodology has been encoded in the TORMIS computer code to facilitate numerical analysis and plant-specific tornado missile probability assessments

  2. Modeling and Analysis of Power Processing Systems (MAPPS). Volume 1: Technical report

    Science.gov (United States)

    Lee, F. C.; Rahman, S.; Carter, R. A.; Wu, C. H.; Yu, Y.; Chang, R.

    1980-01-01

    Computer aided design and analysis techniques were applied to power processing equipment. Topics covered include: (1) discrete time domain analysis of switching regulators for performance analysis; (2) design optimization of power converters using augmented Lagrangian penalty function technique; (3) investigation of current-injected multiloop controlled switching regulators; and (4) application of optimization for Navy VSTOL energy power system. The generation of the mathematical models and the development and application of computer aided design techniques to solve the different mathematical models are discussed. Recommendations are made for future work that would enhance the application of the computer aided design techniques for power processing systems.

  3. Simulation study of a magnetocardiogram based on a virtual heart model: effect of a cardiac equivalent source and a volume conductor

    International Nuclear Information System (INIS)

    Shou Guo-Fa; Xia Ling; Dai Ling; Ma Ping; Tang Fa-Kuan

    2011-01-01

    In this paper, we present a magnetocardiogram (MCG) simulation study using the boundary element method (BEM) and based on the virtual heart model and the realistic human volume conductor model. The different contributions of cardiac equivalent source models and volume conductor models to the MCG are deeply and comprehensively investigated. The single dipole source model, the multiple dipoles source model and the equivalent double layer (EDL) source model are analysed and compared with the cardiac equivalent source models. Meanwhile, the effect of the volume conductor model on the MCG combined with these cardiac equivalent sources is investigated. The simulation results demonstrate that the cardiac electrophysiological information will be partly missed when only the single dipole source is taken, while the EDL source is a good option for MCG simulation and the effect of the volume conductor is smallest for the EDL source. Therefore, the EDL source is suitable for the study of MCG forward and inverse problems, and more attention should be paid to it in future MCG studies. (general)

  4. OLI/ESP Modeling Of The Semi-Integrated Pilot Plant For Estimate Of Campaigns I-IV Simulant Volumes

    International Nuclear Information System (INIS)

    CARL, BARNES

    2004-01-01

    Four SIPP campaigns have been planned to investigate the effect of recycle streams on the RPP-WTP pretreatment process such as the filter flux rate and other areas of interest. This document describes OLI/ESP modeling work done in support of the planning and operation of the SIPP. An existing OLI/ESP steady-state model was expanded to represent the pretreatment system through to the TLP evaporator for the LAW train and the washed sludge for the HLW train. The model was used to investigate alternative operating scenarios, determine the optimum volumetric waste feed ratio of AP-101 to AY-102, and, for each campaign, estimate the simulant and input recycle volumes corresponding to the target glass production rates of 6MT/day HLW glass and 80MT/day LAW glass and scaled to the target of 140L of Campaign I washed sludge. It was designed to quickly achieve steady state and simulation results indicate this was accomplished by Campaign IV. The alternative operating scenarios modeled differed only in the point at which the AP-101 and AY-102 waste feed streams were introduced to the process. The results showed no difference in the production rate between the scenarios. Therefore, for these specific waste feeds the process should be operated to maximize the energy efficiency and minimize scaling in the evaporator by feeding the AY-102 waste feed to the ultra-filtration feed prep tank, bypassing the waste feed evaporator

  5. An analysis of seismic tomography, predicted slab volumes and forward modeled mantle structure of the circum-Arctic

    Science.gov (United States)

    Shephard, Grace; Heine, Christian; Flament, Nicolas; Quevedo, Leonardo; Clarke, Daniel; Seton, Maria; Dietmar Müller, R.

    2013-04-01

    Owing largely to the remoteness of the region, the detailed Mesozoic and Cenozoic kinematic evolution of the circum-Arctic is not well known. Highly dynamic plate boundaries, in particular related to the subduction of plates in northern Panthalassa and the South Anuyi oceans since the Jurassic, adds additional complexity due to fragmentation of the lithosphere into a large number of tectonic blocks. We have integrated key observations from publicly available geological and geophysical datasets to define major tectonic elements and generate a new plate tectonic reconstruction of the circum-Arctic. The time-dependent location of subduction, age of subducted lithosphere, convergence rates and intermittent ridge subduction impart significant effects on the evolution of overriding plates and of the mantle structure. We use our new plate tectonic reconstruction of the circum-Arctic, embedded within a global plate model, to drive forward geodynamic models of mantle flow. We analyse the spatio-temporal evolution of subducted slab volumes in the circum-Arctic and compare the present-day prediction of our model with P and S-wave tomography models.

  6. Model Studies on Acetabular Component Migration in Total Hip Arthroplasty using CT and a Semiautomated Program for Volume Merging

    International Nuclear Information System (INIS)

    Olivecrona, Lotta; Olivecrona, H.; Weidenhielm, L.; Noz, M.E.; Maguire, G.Q. Jr.; Zeleznik, M.P.

    2003-01-01

    Purpose: Validation of a non-invasive CT method for detection of acetabular cup migration after total hip arthroplasty in a phantom study. Material and Methods: 26 CT examinations were obtained of a pelvic model while altering the position of the acetabular cup. Using a previously described program for volume merging, the pelvi in different examinations were fused and the 3D alterations of the position of the acetabular cup were evaluated visually and numerically and correlated to direct measurements on the model. Results: Visually, two independent examiners differentiated between 0, 1 and 2 to 3 mm migration with 100% specificity and sensitivity. Numerically, the mean error over all cases between model and CT measurements was 0.04 mm (SD ± 0.33). The mean absolute error between model and CT data was 0.26 mm (SD ± 0.19). Intra- and interobserver 95% accuracy and repeatability limits were below 0.5/0.7 mm, respectively. No significant interobserver difference occurred. The data were normally distributed and not dependent on observer. Conclusion: The accuracy of this non-invasive method out-performs routine plain radiography. The method gives both visual and numerical correlates to migration and can be used in clinical practice

  7. Validation of Water Erosion Prediction Project (WEPP) model for low-volume forest roads

    Science.gov (United States)

    William Elliot; R. B. Foltz; Charlie Luce

    1995-01-01

    Erosion rates of recently graded nongravel forest roads were measured under rainfall simulation on five different soils. The erosion rates observed on 24 forest road erosion plots were compared with values predicted by the Water Erosion Prediction Project (WEPP) Model, Version 93.1. Hydraulic conductivity and soil erodibility values were predicted from methods...

  8. Mexico City air quality research initiative, volume 3, modeling and simulation

    Energy Technology Data Exchange (ETDEWEB)

    Mauzy, A. [ed.] [Los Alamos National Lab., NM (United States)

    1994-06-01

    The objective of the modeling and simulation task was to develop, test, and apply an appropriate set of models that could translate emission changes into air quality changes. Specifically, we wanted to develop models that could describe how existing measurements of ozone (O{sub 3}), carbon monoxide (CO), and sulfur dioxide (SO{sub 2}) would be expected to change if their emissions were changed. The modeling must be able to address the effects of difference in weather conditions and changes in land use as well as the effects of changes in emission levels. It must also be able to address the effects of changes in the nature and distribution of the emissions as well as changes in the total emissions. A second objective was to provide an understanding of the conditions that lead to poor air quality in Mexico City. We know in a general sense that Mexico City`s poor air quality is the result of large quantities of emissions in a confined area that is subject to light winds, but we did not know much about many aspects of the problem. For example, is the air quality on a given day primarily the result of emissions on that day...or is there an important carryover from previous nights and days? With a good understanding of the important meteorological circumstances that lead to poor air quality, we learn what it take duce an accurate forecast of impending quality so that we can determine the advisability of emergency measures.

  9. Design of Training Systems. Computerization of the Educational Technology Assessment Model. Volume 1.

    Science.gov (United States)

    Duffy, Larry B.; And Others

    The Educational Technology Assessment Model (ETAM) is a set of comprehensive procedures and variables for the analysis, synthesis, and decision making, in regard to the benefits, costs, and risks associated with introducing technical innovations in education and training. This final report summarizes the analysis, design, and development…

  10. Design of Training Systems: Computerization of the Educational Technology Assessment Model (ETAM). Volume 2.

    Science.gov (United States)

    Duffy, Larry R.; And Others

    This is the appendix of the final report (IR 004 981) which summarizes the analysis, design and development activities associated with the Educational Technology Assessment Model (ETAM). It includes the results of a study on the indexing of innovations and the assignment of taxonomic descriptors to courses, job/tasks, and instructional vehicles.…

  11. USAF Logistics Process Optimization Study for the Aircraft Asset Sustainment Process. Volume 3. Future to be Asset Sustainment Process Model

    National Research Council Canada - National Science Library

    Adamson, Anthony

    1998-01-01

    .... It is published as three separate volumes. Volume I, USAF Logistics Process Optimization Study for the Aircraft Asset Sustainment Process -- Phase II Report, discusses the result and cost/benefit analysis of testing three initiatives...

  12. On stability of exponential cosmological solutions with non-static volume factor in the Einstein-Gauss-Bonnet model

    International Nuclear Information System (INIS)

    Ivashchuk, V.D.

    2016-01-01

    A (n + 1)-dimensional gravitational model with Gauss-Bonnet term and a cosmological constant term is considered. When ansatz with diagonal cosmological metrics is adopted, the solutions with an exponential dependence of the scale factors, a i ∝ exp(v i t), i = 1,.., n, are analyzed for n > 3. We study the stability of the solutions with non-static volume factor, i.e. K(v) = sum k=1 n v k ≠ 0. We prove that under a certain restriction R imposed solutions with K(v) > 0 are stable, while solutions with K(v) < 0 are unstable. Certain examples of stable solutions are presented. We show that the solutions with v 1 = v 2 = v 3 = H > 0 and zero variation of the effective gravitational constant are stable if the restriction R is obeyed. (orig.)

  13. On stable exponential cosmological solutions with non-static volume factor in the Einstein-Gauss-Bonnet model

    International Nuclear Information System (INIS)

    Ivashchuk, V D; Ernazarov, K K

    2017-01-01

    A ( n + 1)-dimensional gravitational model with cosmological constant and Gauss-Bonnet term is studied. The ansatz with diagonal cosmological metrics is adopted and solutions with exponential dependence of scale factors: a i ∼ exp ( v i t ), i = 1, …, n , are considered. The stability analysis of the solutions with non-static volume factor is presented. We show that the solutions with v 1 = v 2 = v 3 = H > 0 and small enough variation of the effective gravitational constant G are stable if certain restriction on ( v i ) is obeyed. New examples of stable exponential solutions with zero variation of G in dimensions D = 1 + m + 2 with m > 2 are presented. (paper)

  14. On stability of exponential cosmological solutions with non-static volume factor in the Einstein-Gauss-Bonnet model

    Energy Technology Data Exchange (ETDEWEB)

    Ivashchuk, V.D. [VNIIMS, Center for Gravitation and Fundamental Metrology, Moscow (Russian Federation); Peoples' Friendship University of Russia (RUDN University), Institute of Gravitation and Cosmology, Moscow (Russian Federation)

    2016-08-15

    A (n + 1)-dimensional gravitational model with Gauss-Bonnet term and a cosmological constant term is considered. When ansatz with diagonal cosmological metrics is adopted, the solutions with an exponential dependence of the scale factors, a{sub i} ∝ exp(v{sup i}t), i = 1,.., n, are analyzed for n > 3. We study the stability of the solutions with non-static volume factor, i.e. K(v) = sum {sub k=1}{sup n} v{sup k} ≠ 0. We prove that under a certain restriction R imposed solutions with K(v) > 0 are stable, while solutions with K(v) < 0 are unstable. Certain examples of stable solutions are presented. We show that the solutions with v{sup 1} = v{sup 2} = v{sup 3} = H > 0 and zero variation of the effective gravitational constant are stable if the restriction R is obeyed. (orig.)

  15. Parametric Engineering System Definition Model. Volume II. Appendix C. FORTRAN Listings

    Science.gov (United States)

    1979-08-01

    MODEL . IVOLUME II i .PPENDIX C (TCTRAN ISTINC L !I NO,144 ". l ~July 1979 l ~Contract DAAK30-78-C-O059’ : ~S. Spaulding, A. Weintraub,: ~b ,F...listings for the COMPEND model . The listings are organized as follows: 0 Section C-2 contains the main program, a listing of all labeled COMMON blocks (all...ý LU.U. a V, _j -tL C w It 4c. cc ~ * U- . 0W.(e ozo . LJ.Zm *O-’t L * .jc clf LL’ L;~ LtUC 0’ coI C N M. %t W, - orc & ru..w a’ý Wu. Ln U, U U Ln U

  16. A simulation model for wind energy storage systems. Volume 2: Operation manual

    Science.gov (United States)

    Warren, A. W.; Edsinger, R. W.; Burroughs, J. D.

    1977-01-01

    A comprehensive computer program (SIMWEST) developed for the modeling of wind energy/storage systems utilizing any combination of five types of storage (pumped hydro, battery, thermal, flywheel, and pneumatic) is described. Features of the program include: a precompiler which generates computer models (in FORTRAN) of complex wind source/storage/application systems, from user specifications using the respective library components; a program which provides the techno-economic system analysis with the respective I/O the integration of system dynamics, and the iteration for conveyance of variables; and capability to evaluate economic feasibility as well as general performance of wind energy systems. The SIMWEST operation manual is presented and the usage of the SIMWEST program and the design of the library components are described. A number of example simulations intended to familiarize the user with the program's operation is given along with a listing of each SIMWEST library subroutine.

  17. Towards the development of a fully coupled arterial-venous 1D model: suitability of using a 1D finite volume method with staggered spatial discretization

    CSIR Research Space (South Africa)

    Bogaers, Alfred EJ

    2012-07-01

    Full Text Available In this paper we outline the development of a 1D finite volume model to solve for blood flow through the arterial system. The model is based on a staggered spatial discretization which leads to a stable solution scheme. This scheme can accurately...

  18. A new modelling approach for compacted clayey soils using specific water volume as a state variable

    OpenAIRE

    Abeyrathne, Wedumpuli Koralalage Arunodi Prabashini

    2017-01-01

    One of the key challenges of the present geotechnical engineering community is the accurate definition of unsaturated soil behaviour in routine engineering practice. This is because despite the remarkable progression of unsaturated soil mechanics as a branch of geotechnical engineering over the last few decades, the gap between unsaturated soils research and practice has widened significantly as the models to predict the soil behaviour have become more and more complex. Ther...

  19. BISICLES - A Scalable Finite-Volume Adaptive Mesh Refinement Ice Sheet Model

    Science.gov (United States)

    Martin, D. F.; Cornford, S. L.; Ranken, D. F.; Le Brocq, A. M.; Gladstone, R. M.; Payne, A. J.; Ng, E. G.; Lipscomb, W. H.

    2012-04-01

    Understanding the changing behavior of land ice sheets is essential for accurate projection of sea-level change. The dynamics of ice sheets span a wide range of scales. Localized regions such as grounding lines and ice streams require extremely fine (better than 1 km) resolution to correctly capture the dynamics. Resolving such features using a uniform computational mesh would be prohibitively expensive. Conversely, there are large regions where such fine resolution is unnecessary and represents a waste of computational resources. This makes ice sheets a prime candidate for adaptive mesh refinement (AMR), in which finer spatial resolution is added only where needed, enabling the efficient use of computing resources. The Berkeley ISICLES (BISICLES) project is a collaboration among the Lawrence Berkeley and Los Alamos National Laboratories in the U.S. and the University of Bristol in the U.K. We are constructing a high-performance scalable AMR ice sheet model using the Chombo parallel AMR framework. The placement of refined meshes can easily adapt dynamically to follow the changing and evolving features of the ice sheets. We also use a vertically-integrated treatment of the momentum equation based on that of Schoof and Hindmarsh (2010), which permits additional computational efficiency. Using Chombo enables us to take advantage of existing scalable multigrid-based AMR elliptic solvers and PPM-based AMR hyperbolic solvers. Linking to the existing Glimmer-CISM community ice sheet model as an alternative dynamical core allows use of many features of the existing Glimmer-CISM model, including a coupler to CESM. We present results showing the effectiveness of our approach, both for simple benchmark problems which validate our approach, and for application to regional and continental-scale ice-sheet modeling.

  20. Human Social Culture Behavior Modeling Program Newsletter. Volume 1. Issue 1, Spring 2009

    Science.gov (United States)

    2009-03-30

    ONR Joanna (Jo) Lozano is a new member of the ONR Code 30 HSCB team. Joanna obtained her degree in Leisure & Tourism from Stroud College in...scientifi c and technical programs having supported research projects at DARPA, ONR, and NRL, as well as several studies for the DSB. Joanna Lozano...surfaces, p. 424, New York: Wiley. Harmon, S.Y., & Youngblood, S. M. (2005). A proposed model for simulation valida- tion process maturity. Journal

  1. Heterogeneous Concurrent Modeling and Design in Java (Volume 2: Ptolemy II Software Architecture)

    Science.gov (United States)

    2008-04-01

    opaque entities were called wormholes . 1.6 Concurrency Concurrency is an expected property in many models. Network topologies may represent the...called a wormhole in the earlier generation of Ptolemy. Its ports are opaque and its contents are not visible via methods like deepEntityList(). Recall...conditions 18 readers and writers 20 receiver wormhole ports 48 Receiver interface 30 RecordToken 121 RecordToken class 57 reflection 88, 90 registerClass

  2. Modeling Respiratory Gas Dynamics in the Aviator’s Breathing System. Volume 1

    Science.gov (United States)

    1994-05-01

    tricuspid valve which is presumed to track intrathoracic pressure. The pressures and flows in the various segments are coupled by their spatial connections...function in clinically significant pulmonary disease or for teaching respiratory physiology.’Ŗ’,13,14,15,16.17 Unfortunately, these were developed for...inspiratory valve model relates the flow and pressures between the mask supply hose and the oronasal cavity during inspiration. The expiratory valve

  3. Using four-phase Eulerian volume averaging approach to model macrosegregation and shrinkage cavity

    Science.gov (United States)

    Wu, M.; Kharicha, A.; Ludwig, A.

    2015-06-01

    This work is to extend a previous 3-phase mixed columnar-equiaxed solidification model to treat the formation of shrinkage cavity by including an additional phase. In the previous model the mixed columnar and equiaxed solidification with consideration of multiphase transport phenomena (mass, momentum, species and enthalpy) is proposed to calculate the as- cast structure including columnar-to-equiaxed transition (CET) and formation of macrosegregation. In order to incorporate the formation of shrinkage cavity, an additional phase, i.e. gas phase or covering liquid slag phase, must be considered in addition to the previously introduced 3 phases (parent melt, solidifying columnar dendrite trunks and equiaxed grains). No mass and species transfer between the new and other 3 phases is necessary, but the treatment of the momentum and energy exchanges between them is crucially important for the formation of free surface and shrinkage cavity, which in turn influences the flow field and formation of segregation. A steel ingot is preliminarily calculated to exam the functionalities of the model.

  4. International Space Station Human Behavior and Performance Competency Model: Volume I

    Science.gov (United States)

    Schmidt, Lacey

    2008-01-01

    This document defines Human Behavior and Performance (HBP) competencies that are recommended to be included as requirements to participate in international long duration missions. They were developed in response to the Multilateral Crew Operations Panel (MMOP) request to develop HBP training requirements for the International Space Station (ISS). The competency model presented here was developed by the ITCB HBPT WG and forms the basis for determining the HBP training curriculum for long duration crewmembers. This document lists specific HBP competencies and behaviors required of astronauts/cosmonauts who participate in ISS expedition and other international longduration missions. Please note that this model does not encompass all competencies required. For example, outside the scope of this document are cognitive skills and abilities, including but not limited to concentration, memorization, perception, imagination, and thinking. It is assumed that these skills, which are crucial in terms of human behavior and performance, are considered during selection phase since such professionally significant qualities of the operator should be taken into consideration in order to ensure sufficient baseline levels that can be further improved during general astronaut training. Also, technical competencies, even though critical for crewmembers, are beyond the scope of this document. It should also be noted that the competencies in this model (and subsequent objectives) are not intended to limit the internal activities or training programs of any international partner.

  5. MARS code manual volume I: code structure, system models, and solution methods

    International Nuclear Information System (INIS)

    Chung, Bub Dong; Kim, Kyung Doo; Bae, Sung Won; Jeong, Jae Jun; Lee, Seung Wook; Hwang, Moon Kyu; Yoon, Churl

    2010-02-01

    Korea Advanced Energy Research Institute (KAERI) conceived and started the development of MARS code with the main objective of producing a state-of-the-art realistic thermal hydraulic systems analysis code with multi-dimensional analysis capability. MARS achieves this objective by very tightly integrating the one dimensional RELAP5/MOD3 with the multi-dimensional COBRA-TF codes. The method of integration of the two codes is based on the dynamic link library techniques, and the system pressure equation matrices of both codes are implicitly integrated and solved simultaneously. In addition, the Equation-Of-State (EOS) for the light water was unified by replacing the EOS of COBRA-TF by that of the RELAP5. This theory manual provides a complete list of overall information of code structure and major function of MARS including code architecture, hydrodynamic model, heat structure, trip / control system and point reactor kinetics model. Therefore, this report would be very useful for the code users. The overall structure of the manual is modeled on the structure of the RELAP5 and as such the layout of the manual is very similar to that of the RELAP. This similitude to RELAP5 input is intentional as this input scheme will allow minimum modification between the inputs of RELAP5 and MARS3.1. MARS3.1 development team would like to express its appreciation to the RELAP5 Development Team and the USNRC for making this manual possible

  6. Analysis of Composite Skin-Stiffener Debond Specimens Using Volume Elements and a Shell/3D Modeling Technique

    Science.gov (United States)

    Krueger, Ronald; Minguet, Pierre J.; Bushnell, Dennis M. (Technical Monitor)

    2002-01-01

    The debonding of a skin/stringer specimen subjected to tension was studied using three-dimensional volume element modeling and computational fracture mechanics. Mixed mode strain energy release rates were calculated from finite element results using the virtual crack closure technique. The simulations revealed an increase in total energy release rate in the immediate vicinity of the free edges of the specimen. Correlation of the computed mixed-mode strain energy release rates along the delamination front contour with a two-dimensional mixed-mode interlaminar fracture criterion suggested that in spite of peak total energy release rates at the free edge the delamination would not advance at the edges first. The qualitative prediction of the shape of the delamination front was confirmed by X-ray photographs of a specimen taken during testing. The good correlation between prediction based on analysis and experiment demonstrated the efficiency of a mixed-mode failure analysis for the investigation of skin/stiffener separation due to delamination in the adherents. The application of a shell/3D modeling technique for the simulation of skin/stringer debond in a specimen subjected to three-point bending is also demonstrated. The global structure was modeled with shell elements. A local three-dimensional model, extending to about three specimen thicknesses on either side of the delamination front was used to capture the details of the damaged section. Computed total strain energy release rates and mixed-mode ratios obtained from shell/3D simulations were in good agreement with results obtained from full solid models. The good correlations of the results demonstrated the effectiveness of the shell/3D modeling technique for the investigation of skin/stiffener separation due to delamination in the adherents.

  7. Joint Ecosystem Modeling (JEM) ecological model documentation volume 1: Estuarine prey fish biomass availability v1.0.0

    Science.gov (United States)

    Romañach, Stephanie S.; Conzelmann, Craig; Daugherty, Adam; Lorenz, Jerome L.; Hunnicutt, Christina; Mazzotti, Frank J.

    2011-01-01

    Estuarine fish serve as an important prey base in the Greater Everglades ecosystem for key fauna such as wading birds, crocodiles, alligators, and piscivorous fishes. Human-made changes to freshwater flow across the Greater Everglades have resulted in less freshwater flow into the fringing estuaries and coasts. These changes in freshwater input have altered salinity patterns and negatively affected primary production of the estuarine fish prey base. Planned restoration projects should affect salinity and water depth both spatially and temporally and result in an increase in appropriate water conditions in areas occupied by estuarine fish. To assist in restoration planning, an ecological model of estuarine prey fish biomass availability was developed as an evaluation tool to aid in the determination of acceptable ranges of salinity and water depth. Comparisons of model output to field data indicate that the model accurately predicts prey biomass in the estuarine regions of the model domain. This model can be used to compare alternative restoration plans and select those that provide suitable conditions.

  8. Two-stage Lagrangian modeling of ignition processes in ignition quality tester and constant volume combustion chambers

    KAUST Repository

    Alfazazi, Adamu

    2016-08-10

    The ignition characteristics of isooctane and n-heptane in an ignition quality tester (IQT) were simulated using a two-stage Lagrangian (TSL) model, which is a zero-dimensional (0-D) reactor network method. The TSL model was also used to simulate the ignition delay of n-dodecane and n-heptane in a constant volume combustion chamber (CVCC), which is archived in the engine combustion network (ECN) library (http://www.ca.sandia.gov/ecn). A detailed chemical kinetic model for gasoline surrogates from the Lawrence Livermore National Laboratory (LLNL) was utilized for the simulation of n-heptane and isooctane. Additional simulations were performed using an optimized gasoline surrogate mechanism from RWTH Aachen University. Validations of the simulated data were also performed with experimental results from an IQT at KAUST. For simulation of n-dodecane in the CVCC, two n-dodecane kinetic models from the literature were utilized. The primary aim of this study is to test the ability of TSL to replicate ignition timings in the IQT and the CVCC. The agreement between the model and the experiment is acceptable except for isooctane in the IQT and n-heptane and n-dodecane in the CVCC. The ability of the simulations to replicate observable trends in ignition delay times with regard to changes in ambient temperature and pressure allows the model to provide insights into the reactions contributing towards ignition. Thus, the TSL model was further employed to investigate the physical and chemical processes responsible for controlling the overall ignition under various conditions. The effects of exothermicity, ambient pressure, and ambient oxygen concentration on first stage ignition were also studied. Increasing ambient pressure and oxygen concentration was found to shorten the overall ignition delay time, but does not affect the timing of the first stage ignition. Additionally, the temperature at the end of the first stage ignition was found to increase at higher ambient pressure

  9. A finite-volume model of a parabolic trough photovoltaic/thermal collector: Energetic and exergetic analyses

    International Nuclear Information System (INIS)

    Calise, Francesco; Palombo, Adolfo; Vanoli, Laura

    2012-01-01

    This paper presents a detailed finite-volume model of a concentrating photovoltaic/thermal (PVT) solar collector. The PVT solar collector consists in a parabolic trough concentrator and a linear triangular receiver. The bottom surfaces of the triangular receiver are equipped with triple-junction cells whereas the top surface is covered by an absorbing surface. The cooling fluid (water) flows inside a channel along the longitudinal direction of the PVT collector. The system was discretized along its axis and, for each slice of the discretized computational domain, mass and energy balances were considered. The model allows one to evaluate both thermodynamic and electrical parameters along the axis of the PVT collector. Then, for each slice of the computational domain, exergy balances were also considered in order to evaluate the corresponding exergy destruction rate and exergetic efficiency. Therefore, the model also calculates the magnitude of the irreversibilities inside the collector and it allows one to detect where these irreversibilities occur. A sensitivity analysis is also performed with the scope to evaluate the effect of the variation of the main design/environmental parameters on the energetic and exergetic performance of the PVT collector. -- Highlights: ► The paper investigates an innovative concentrating photovoltaic thermal solar collector. ► The collector is equipped with triple-junction photovoltaic layers. ► A local exergetic analysis is performed in order to detect sources of irreversibilities. ► Irreversibilities are mainly due to the heat transfer between sun and PVT collector.

  10. Respiratory system model for quasistatic pulmonary pressure-volume (P-V) curve: inflation-deflation loop analyses.

    Science.gov (United States)

    Amini, R; Narusawa, U

    2008-06-01

    A respiratory system model (RSM) is developed for the deflation process of a quasistatic pressure-volume (P-V) curve, following the model for the inflation process reported earlier. In the RSM of both the inflation and the deflation limb, a respiratory system consists of a large population of basic alveolar elements, each consisting of a piston-spring-cylinder subsystem. A normal distribution of the basic elements is derived from Boltzmann statistical model with the alveolar closing (opening) pressure as the distribution parameter for the deflation (inflation) process. An error minimization by the method of least squares applied to existing P-V loop data from two different data sources confirms that a simultaneous inflation-deflation analysis is required for an accurate determination of RSM parameters. Commonly used terms such as lower inflection point, upper inflection point, and compliance are examined based on the P-V equations, on the distribution function, as well as on the geometric and physical properties of the basic alveolar element.

  11. Another look at volume self-calibration: calibration and self-calibration within a pinhole model of Scheimpflug cameras

    International Nuclear Information System (INIS)

    Cornic, Philippe; Le Besnerais, Guy; Champagnat, Frédéric; Illoul, Cédric; Cheminet, Adam; Le Sant, Yves; Leclaire, Benjamin

    2016-01-01

    We address calibration and self-calibration of tomographic PIV experiments within a pinhole model of cameras. A complete and explicit pinhole model of a camera equipped with a 2-tilt angles Scheimpflug adapter is presented. It is then used in a calibration procedure based on a freely moving calibration plate. While the resulting calibrations are accurate enough for Tomo-PIV, we confirm, through a simple experiment, that they are not stable in time, and illustrate how the pinhole framework can be used to provide a quantitative evaluation of geometrical drifts in the setup. We propose an original self-calibration method based on global optimization of the extrinsic parameters of the pinhole model. These methods are successfully applied to the tomographic PIV of an air jet experiment. An unexpected by-product of our work is to show that volume self-calibration induces a change in the world frame coordinates. Provided the calibration drift is small, as generally observed in PIV, the bias on the estimated velocity field is negligible but the absolute location cannot be accurately recovered using standard calibration data. (paper)

  12. A novel experimental model of erectile dysfunction in rats with heart failure using volume overload.

    Directory of Open Access Journals (Sweden)

    Fábio Henrique Silva

    Full Text Available Patients with heart failure (HF display erectile dysfunction (ED. However, the pathophysiology of ED during HF remains poorly investigated.This study aimed to characterize the aortocaval fistula (ACF rat model associated with HF as a novel experimental model of ED. We have undertaken molecular and functional studies to evaluate the alterations of the nitric oxide (NO pathway, autonomic nervous system and oxidative stress in the penis.Male rats were submitted to ACF for HF induction. Intracavernosal pressure in anesthetized rats was evaluated. Concentration-response curves to contractile (phenylephrine and relaxant agents (sodium nitroprusside; SNP, as well as to electrical field stimulation (EFS, were obtained in the cavernosal smooth muscle (CSM strips from sham and HF rats. Protein expression of endothelial NO synthase (eNOS and neuronal NO synthase (nNOS and phosphodiestarese-5 in CSM were evaluated, as well as NOX2 (gp91phox and superoxide dismutase (SOD mRNA expression. SOD activity and thiobarbituric acid reactive substances (TBARs were also performed in plasma.HF rats display erectile dysfunction represented by decreased ICP responses compared to sham rats. The neurogenic contractile responses elicited by EFS were greater in CSM from the HF group. Likewise, phenylephrine-induced contractions were greater in CSM from HF rats. Nitrergic response induced by EFS were decreased in the cavernosal tissue, along with lower eNOS, nNOS and phosphodiestarese-5 protein expressions. An increase of NOX2 and SOD mRNA expression in CSM and plasma TBARs of HF group were detected. Plasma SOD activity was decreased in HF rats.ED in HF rats is associated with decreased NO bioavailability in erectile tissue due to eNOS/nNOS dowregulation and NOX2 upregulation, as well as hypercontractility of the penis. This rat model of ACF could be a useful tool to evaluate the molecular alterations of ED associated with HF.

  13. DIVWAG Model Documentation. Volume II. Programmer/Analyst Manual. Part 1.

    Science.gov (United States)

    1976-07-01

    Routine GCLAST IV-7-B-58 IV-7-B-15 Routine GUPDAT IV-7-B-63 IV-7-C- la Unit Geometry and Target Acquisition Sample Output From Ground Combat Model IV-7-C-2...OMTDATFLE 52, EQUI1HENT ON TRAIKS DATA AND INDEXES LISTRI EDEQUIPIIENT -DIATA Figure II-3-B-3. Routine DMPTOE. (Concluded) II-3-B-19 LA (6) Block L206...READ A CARD 4 EOF YES CARD ? AC LL ENTRIES YES ON CARDTA PROCE S NO L14 ERROR YES PRINT ® IN ENTRY? ERROR MSSAGE NO 7 ENTRY CELL NUBE TERRAIN DATA

  14. Open standards for cascade models for RHIC: Volume 1. Proceedings of RIKEN BNL Research Center workshop

    International Nuclear Information System (INIS)

    1997-01-01

    It is widely recognized that cascade models are potentially effective and powerful tools for interpreting and predicting multi-particle observables in heavy ion physics. However, the lack of common standards, documentation, version control, and accessibility have made it difficult to apply objective scientific criteria for evaluating the many physical and algorithmic assumptions or even to reproduce some published results. The first RIKEN Research Center workshop was proposed by Yang Pang to address this problem by establishing open standards for original codes for applications to nuclear collisions at RHIC energies. The aim of this first workshop is: (1) to prepare a WWW depository site for original source codes and detailed documentation with examples; (2) to develop and perform standardized test for the models such as Lorentz invariance, kinetic theory comparisons, and thermodynamic simulations; (3) to publish a compilation of results of the above work in a journal e.g., ''Heavy Ion Physics''; and (4) to establish a policy statement on a set of minimal requirements for inclusion in the OSCAR-WWW depository

  15. Corporate Data Network (CDN) data requirements task. Enterprise Model. Volume 1

    International Nuclear Information System (INIS)

    1985-11-01

    The NRC has initiated a multi-year program to centralize its information processing in a Corporate Data Network (CDN). The new information processing environment will include shared databases, telecommunications, office automation tools, and state-of-the-art software. Touche Ross and Company was contracted with to perform a general data requirements analysis for shared databases and to develop a preliminary plan for implementation of the CDN concept. The Enterprise Model (Vol. 1) provided the NRC with agency-wide information requirements in the form of data entities and organizational demand patterns as the basis for clustering the entities into logical groups. The Data Dictionary (Vol. 2) provided the NRC with definitions and example attributes and properties for each entity. The Data Model (Vol. 3) defined logical databases and entity relationships within and between databases. The Preliminary Strategic Data Plan (Vol. 4) prioritized the development of databases and included a workplan and approach for implementation of the shared database component of the Corporate Data Network

  16. Numerical Simulation of High Intensity Focused Ultrasound Therapy with Volume Model of Human Body

    Science.gov (United States)

    Okita, Kohei; Sugiyama, Kazuyasu; Ono, Kenji; Takagi, Shu; Matsumoto, Yoichiro

    2010-03-01

    The development of the HIFU therapy for the deeply placed cancer has been desired. On problem is the displacement of the focal point due to the inhomogeneity of human body. The objectives are to realize the appropriate phase control of an array transducer and to support the preoperative planning of HIFU therapy by the computational prediction of treatment regions. Our approach is to solve the mass and momentum equations for mixture with the equation of state of media. The heat equation with a heat source of a viscous dissipation is solved to estimate the ablation region of tissue. The ablation, i.e., the heat denaturation of protein, is modeled as a phase transition by the phase field model. The HIFU therapy with a bowl-shape array transducer for a liver cancer is simulated. As the result with a phase control, we obtain a clear focus which is closer to a target point than the focus without a phase control, when the ultrasound propagates through lib bones. In addition, the development of the ablation region is reproduced numerically.

  17. Three-dimensional finite volume modelling of blood flow in simulated angular neck abdominal aortic aneurysm

    Science.gov (United States)

    Algabri, Y. A.; Rookkapan, S.; Chatpun, S.

    2017-09-01

    An abdominal aortic aneurysm (AAA) is considered a deadly cardiovascular disease that defined as a focal dilation of blood artery. The healthy aorta size is between 15 and 24 mm based on gender, bodyweight, and age. When the diameter increased to 30 mm or more, the rupture can occur if it is kept growing or untreated. Moreover, the proximal angular neck of aneurysm is categorized as a significant morphological feature with prime harmful effects on endovascular aneurysm repair (EVAR). Flow pattern in pathological vessel can influence the vascular intervention. The aim of this study is to investigate the blood flow behaviours in angular neck abdominal aortic aneurysm with simulated geometry based on patient’s information using computational fluid dynamics (CFD). The 3D angular neck AAA models have been designed by using SolidWorks Software. Consequently, CFD tools are used for simulating these 3D models of angular neck AAA in ANSYS FLUENT Software. Eventually, based on the results, we summarized that the CFD techniques have shown high performance in explaining and investigating the flow patterns for angular neck abdominal aortic aneurysm.

  18. Automated segmentation of mouse OCT volumes (ASiMOV): Validation & clinical study of a light damage model.

    Science.gov (United States)

    Antony, Bhavna Josephine; Kim, Byung-Jin; Lang, Andrew; Carass, Aaron; Prince, Jerry L; Zack, Donald J

    2017-01-01

    The use of spectral-domain optical coherence tomography (SD-OCT) is becoming commonplace for the in vivo longitudinal study of murine models of ophthalmic disease. Longitudinal studies, however, generate large quantities of data, the manual analysis of which is very challenging due to the time-consuming nature of generating delineations. Thus, it is of importance that automated algorithms be developed to facilitate accurate and timely analysis of these large datasets. Furthermore, as the models target a variety of diseases, the associated structural changes can also be extremely disparate. For instance, in the light damage (LD) model, which is frequently used to study photoreceptor degeneration, the outer retina appears dramatically different from the normal retina. To address these concerns, we have developed a flexible graph-based algorithm for the automated segmentation of mouse OCT volumes (ASiMOV). This approach incorporates a machine-learning component that can be easily trained for different disease models. To validate ASiMOV, the automated results were compared to manual delineations obtained from three raters on healthy and BALB/cJ mice post LD. It was also used to study a longitudinal LD model, where five control and five LD mice were imaged at four timepoints post LD. The total retinal thickness and the outer retina (comprising the outer nuclear layer, and inner and outer segments of the photoreceptors) were unchanged the day after the LD, but subsequently thinned significantly (p < 0.01). The retinal nerve fiber-ganglion cell complex and the inner plexiform layers, however, remained unchanged for the duration of the study.

  19. User manual for GEOCITY: a computer model for cost analysis of geothermal district-heating-and-cooling systems. Volume II. Appendices

    Energy Technology Data Exchange (ETDEWEB)

    Huber, H.D.; Fassbender, L.L.; Bloomster, C.H.

    1982-09-01

    The purpose of this model is to calculate the costs of residential space heating, space cooling, and sanitary water heating or process heating (cooling) using geothermal energy from a hydrothermal reservoir. The model can calculate geothermal heating and cooling costs for residential developments, a multi-district city, or a point demand such as an industrial factory or commercial building. Volume II contains all the appendices, including cost equations and models for the reservoir and fluid transmission system and the distribution system, descriptions of predefined residential district types for the distribution system, key equations for the cooling degree hour methodology, and a listing of the sample case output. Both volumes include the complete table of contents and lists of figures and tables. In addition, both volumes include the indices for the input parameters and subroutines defined in the user manual.

  20. Transonic wind tunnel tests of a .015 scale space shuttle orbiter model, volume 2

    Science.gov (United States)

    Struzynski, N. A.

    1975-01-01

    Transonic wind tunnel tests were run on a 0.015 scale model of the Space Shuttle Orbiter Vehicle in an eight-foot tunnel during August 1975. The purpose of the program was to obtain basic shuttle aerodynamic data through a full range of elevon and aileron deflections, verification of data obtained at other facilities, and effects of Reynolds numbers. The second part of a discussion of test procedures and results in both tabular and graphical form were presented. Tests were performed at Mach numbers from 0.35 to 1.20, and at Reynolds numbers from 3.5 million to 8.2 million per foot. The angle of attack was varied from -2 to +20 degrees at sideslip angles of -2, 0, +2 degrees. Sideslip was varied from -6 to +8 degrees at constant angles of attack from 0 to +20 degrees. Various aileron and ailevon settings were tested for various angles of attack.

  1. Transonic wind tunnel tests of A.015 scale space shuttle orbiter model, volume 1

    Science.gov (United States)

    Struzynski, N. A.

    1975-01-01

    Transonic wind tunnel tests were run on a 0.015 scale model of the Space Shuttle Orbiter Vehicle in an eight-foot tunnel during August 1975. The purpose of the program was to obtain basic shuttle aerodynamic data through a full range of elevon and aileron deflections, verification of data obtained at other facilities, and effects of Reynolds numbers. The first part of a discussion of test procedures and results in both tabular and graphical form were presented. Tests were performed at Mach numbers from 0.35 to 1.20, and at Reynolds numbers for 3.5 million to 8.2 million per foot. The angle of attack was varied from -1 to +20 degrees at sideslip angles of -2, 0, +2 degrees. Sideslip was varied from -6 to +8 degrees at constant angles of attack from 0 to +20 degrees. Various aileron and ailevon settings were tested for various angles of attack.

  2. A NASTRAN Vibration Model of the AH-1G Helicopter Airframe. Volume 2

    Science.gov (United States)

    1974-06-01

    finite ele - ment model is explained. The NASTRAN input data deck serves as a major portion of the documentation. **y ii UNCLASSIFIED SECjBlTV...xttX’S.ujet&etrt.LiixtxiXrt *u el nt % ft JJ t t -L r r. T z ’,’TZ;~zzzz.v.zrz.zzxrz**. z z z z z z. ? * z t 9 * T...rtOi\\tA7 ^«>i/,*-»^’***(7>O^**e0’^OrtO^ #3’ — 0*’N*’"— — «O^O-^ÄOOO« Ö K m >g ■»»n — #(*■«■# — ^fg^ oiDO -«*-»- « CO (B ’ *#^ ^i O

  3. Performance and cost models for the direct sulfur recovery process. Task 1 Topical report, Volume 3

    Energy Technology Data Exchange (ETDEWEB)

    Frey, H.C. [North Carolina State Univ., Raleigh, NC (United States); Williams, R.B. [Carneigie Mellon Univ., Pittsburgh, PA (United States)

    1995-09-01

    The purpose of this project is to develop performance and cost models of the Direct Sulfur Recovery Process (DSRP). The DSRP is an emerging technology for sulfur recovery from advanced power generation technologies such as Integrated Gasification Combined Cycle (IGCC) systems. In IGCC systems, sulfur present in the coal is captured by gas cleanup technologies to avoid creating emissions of sulfur dioxide to the atmosphere. The sulfur that is separated from the coal gas stream must be collected. Leading options for dealing with the sulfur include byproduct recovery as either sulfur or sulfuric acid. Sulfur is a preferred byproduct, because it is easier to handle and therefore does not depend as strongly upon the location of potential customers as is the case for sulfuric acid. This report describes the need for new sulfur recovery technologies.

  4. Global fractional anisotropy and mean diffusivity together with segmented brain volumes assemble a predictive discriminant model for young and elderly healthy brains: a pilot study at 3T

    Science.gov (United States)

    Garcia-Lazaro, Haydee Guadalupe; Becerra-Laparra, Ivonne; Cortez-Conradis, David; Roldan-Valadez, Ernesto

    2016-01-01

    Summary Several parameters of brain integrity can be derived from diffusion tensor imaging. These include fractional anisotropy (FA) and mean diffusivity (MD). Combination of these variables using multivariate analysis might result in a predictive model able to detect the structural changes of human brain aging. Our aim was to discriminate between young and older healthy brains by combining structural and volumetric variables from brain MRI: FA, MD, and white matter (WM), gray matter (GM) and cerebrospinal fluid (CSF) volumes. This was a cross-sectional study in 21 young (mean age, 25.71±3.04 years; range, 21–34 years) and 10 elderly (mean age, 70.20±4.02 years; range, 66–80 years) healthy volunteers. Multivariate discriminant analysis, with age as the dependent variable and WM, GM and CSF volumes, global FA and MD, and gender as the independent variables, was used to assemble a predictive model. The resulting model was able to differentiate between young and older brains: Wilks’ λ = 0.235, χ2 (6) = 37.603, p = .000001. Only global FA, WM volume and CSF volume significantly discriminated between groups. The total accuracy was 93.5%; the sensitivity, specificity and positive and negative predictive values were 91.30%, 100%, 100% and 80%, respectively. Global FA, WM volume and CSF volume are parameters that, when combined, reliably discriminate between young and older brains. A decrease in FA is the strongest predictor of membership of the older brain group, followed by an increase in WM and CSF volumes. Brain assessment using a predictive model might allow the follow-up of selected cases that deviate from normal aging. PMID:27027893

  5. Development of a dynamic model to evaluate economic recovery following a nuclear attack. Volume 2. Model equations (appendices C and D). Final report

    International Nuclear Information System (INIS)

    Peterson, D.W.; Silverman, W.S.; Weil, H.B.; Willard, S.

    1980-11-01

    A highly-robust, dynamic simulation model of the US economy has been constructed to evaluate the likely economic response after various nuclear attacks or other severe disruptions, under various policies and assumptions. The model consists of a large system of nonlinear, recursive, time-difference equations. The solution-interval of the model is adjustable, with a maximum value of three weeks. The model represents the economy in thirteen sectors. Each sector contains a detailed representation of production, distribution, supply constraints, finance, employment, pricing, and wages. Also included are a full input-output representation of the interconnections among the sectors, and the psychological responses of corporate planners, consumers, and the labor force. The model's equations are formulated to remain consistent and realistic for all values of the variables, including the most extreme conditions. Therefore, the model can realistically simulate any degree or time sequence of nuclear attacks, pre-attack surges, mobilization, or policy shifts. Simulation experiments with the model suggest that the economy is highly vulnerable to nuclear attack, and that recovery requires extensive preparation, including psychological readiness, technology maintenance, special financial policies, and (if possible) maintenance of foreign trade. Civil defense policies must be adaptive (contingent on the nature of the damage) and must strive for balance among sectors, rather than maximum survival. The simulation model itself consists of an interrelated set of mathematical equations, written in the computer language DYNAMO. Two appendices to the report are presented in this volume. Appendix C gives a brief introduction to the conventions and notations of the DYNAMO language. The equations, definitions, and variables of the model are listed in Appendix D. For the convenience of the reader, these two appendices are bound separately

  6. Technical Report Series on Global Modeling and Data Assimilation, Volume 41 : GDIS Workshop Report

    Science.gov (United States)

    Koster, Randal D. (Editor); Schubert, Siegfried; Pozzi, Will; Mo, Kingtse; Wood, Eric F.; Stahl, Kerstin; Hayes, Mike; Vogt, Juergen; Seneviratne, Sonia; Stewart, Ron; hide

    2015-01-01

    The workshop "An International Global Drought Information System Workshop: Next Steps" was held on 10-13 December 2014 in Pasadena, California. The more than 60 participants from 15 countries spanned the drought research community and included select representatives from applications communities as well as providers of regional and global drought information products. The workshop was sponsored and supported by the US National Integrated Drought Information System (NIDIS) program, the World Climate Research Program (WCRP: GEWEX, CLIVAR), the World Meteorological Organization (WMO), the Group on Earth Observations (GEO), the European Commission Joint Research Centre (JRC), the US Climate Variability and Predictability (CLIVAR) program, and the US National Oceanic and Atmospheric Administration (NOAA) programs on Modeling, Analysis, Predictions and Projections (MAPP) and Climate Variability & Predictability (CVP). NASA/JPL hosted the workshop with logistical support provided by the GEWEX program office. The goal of the workshop was to build on past Global Drought Information System (GDIS) progress toward developing an experimental global drought information system. Specific goals were threefold: (i) to review recent research results focused on understanding drought mechanisms and their predictability on a wide range of time scales and to identify gaps in understanding that could be addressed by coordinated research; (ii) to help ensure that WRCP research priorities mesh with efforts to build capacity to address drought at the regional level; and (iii) to produce an implementation plan for a short duration pilot project to demonstrate current GDIS capabilities. See http://www.wcrp-climate.org/gdis-wkshp-2014-objectives for more information.

  7. A subaqueous eruption model for shallow-water, small volume eruptions: Evidence from two Precambrian examples

    Science.gov (United States)

    Mueller, Wulf U.

    Ancient, shallow-water, pyroclastic deposits are identified in the Paleoproterozoic Ketilidian Mobile belt, southeast Greenland at Kangerluluk and in the Neoproterozoic Gariep belt of Namibia in the Schakalsberg Mountains. The 1-30 m-thick tuff and lapilli tuff deposits are interpreted as eruption-fed density current deposits emanating from tephra jets that collapsed under subaqueous conditions due to water ingress. The presence of 1-10 mm diameter armoured lapilli, with a central vesicular lapillus or shard, suggests the existence of high velocity, gas, water vapour, and particle-rich tephra jets. A transition from a gas-steam supported tephra jet to a cold water-laden density current without an intermediate stage of storage and remobilization is inferred. Interpretation of a 5-15 m-thick lapilli tuff breccia further supports explosive subaqueous mechanisms. Pyroclasts in the lapilli tuff breccia are interpreted as bombs emplaced ballistically. Multiple bomb sags produced by the impact of rounded juvenile crystal-rich pyroclasts required a water-exclusion zone formed either by a continuous magma uprush or multiple jet activity occurring concurrently, rather than as isolated tephra jets. Intercalated density current deposits indicate uprush events of limited duration and their recurrence with rapid collapse after each pulse. A new subaqueous Surtseyan-type eruption model is proposed based on observations from these two Precambrian study areas.

  8. Cirurgia de redução do volume pulmonar em modelo experimental de enfisema em ratos Lung volume reduction surgery in an experimental rat model of emphysema

    Directory of Open Access Journals (Sweden)

    Laerte Brasiliense Fusco

    2005-02-01

    Full Text Available INTRODUÇÃO: A cirurgia redutora do volume pulmonar pode ser uma opção para portadores de enfisema com grave limitação ventilatória. OBJETIVO: Avaliar funcional e morfologicamente pulmões enfisematosos antes e depois da cirurgia de redução de volume pulmonar, através de modelo experimental em ratos. MÉTODO: Dois grupos experimentais de ratos Wistar foram estabelecidos (papaína sem cirurgia e papaína com cirurgia, e três grupos controle (solução fisiológica sem cirurgia, solução fisiológica com cirurgia e papaína sem ventilação mecânica. Após cerca de 40 dias da instilação intratraqueal da solução de papaína ou fisiológica, os animais dos grupos papaína com cirurgia e solução fisiológica com cirurgia foram submetidos a bilobectomia média e retrocava através de toracotomia direita. Após uma semana, foram submetidos a mecânica ventilatória, com medidas de elastância e resistência das vias aéreas. O tecido pulmonar de todos os animais foi analisado quanto ao diâmetro alveolar médio e quantidade de fibras elásticas. RESULTADOS: A análise morfométrica revelou médias superiores de diâmetro alveolar médio nos pulmões dos grupos submetidos à papaína em comparação com a solução fisiológica. A quantificação de fibras elásticas de septos alveolares dos animais tratados com papaína foi menor que daqueles com solução fisiológica. A elastância dos animais submetidos à bilobectomia e papaína foi maior que a dos submetidos à papaína sem cirurgia e estatisticamente igual aos submetidos à solução fisiológica com e sem cirurgia. CONCLUSÃO: A capacidade de recolhimento elástico do sistema respiratório dos animais com enfisema pulmonar submetidos à redução de volume pulmonar através da bilobectomia retornou a valores equivalentes aos dos grupos controle.BACKGROUND: Lung volume reduction surgery may be a viable treatment alternative for emphysema patients suffering from severe

  9. DEVELOPMENT OF A NATURAL GAS SYSTEMS ANALYSIS MODEL (GSAM) VOLUME I - SUMMARY REPORT VOLUME II - USER'S GUIDE VOLUME IIIA - RP PROGRAMMER'S GUIDE VOLUME IIIB - SRPM PROGRAMMER'S GUIDE VOLUME IIIC - E and P PROGRAMMER'S GUIDE VOLUME IIID - D and I PROGRAMMER'S GUIDE

    International Nuclear Information System (INIS)

    2001-01-01

    This report summarizes work completed on DOE Contract DE-AC21-92MC28138, Development of a Natural Gas Systems Analysis Model (GSAM). The products developed under this project directly support the National Energy Technology Laboratory (NETL) in carrying out its natural gas R and D mission. The objective of this research effort has been to create a comprehensive, non-proprietary, microcomputer model of the North American natural gas market. GSAM has been developed to explicitly evaluate components of the natural gas system, including the entire in-place gas resource base, exploration and development technologies, extraction technology and performance parameters, transportation and storage factors, and end-use demand issues. The system has been fully tested and calibrated and has been used for multiple natural gas metrics analyses at NETL in which metric associated with NETL natural gas upstream R and D technologies and strategies under the direction of NETL has been evaluated. NETL's Natural Gas Strategic Plan requires that R and D activities be evaluated for their ability to provide adequate supplies of reasonably priced natural gas. GSAM provides the capability to assess potential and on-going R and D projects using a full fuel cycle, cost-benefit approach. This method yields realistic, market-based assessments of benefits and costs of alternative or related technology advances. GSAM is capable of estimating both technical and commercial successes, quantifying the potential benefits to the market, as well as to other related research. GSAM, therefore, represents an integration of research activities and a method for planning and prioritizing efforts to maximize benefits and minimize costs. Without an analytical tool like GSAM, NETL natural gas upstream R and D activities cannot be appropriately ranked or focused on the most important aspects of natural gas extraction efforts or utilization considerations

  10. DEVELOPMENT OF A NATURAL GAS SYSTEMS ANALYSIS MODEL (GSAM) VOLUME I - SUMMARY REPORT VOLUME II - USER'S GUIDE VOLUME IIIA - RP PROGRAMMER'S GUIDE VOLUME IIIB - SRPM PROGRAMMER'S GUIDE VOLUME IIIC - E&P PROGRAMMER'S GUIDE VOLUME IIID - D&I PROGRAMMER'S GUIDE

    Energy Technology Data Exchange (ETDEWEB)

    Unknown

    2001-02-01

    This report summarizes work completed on DOE Contract DE-AC21-92MC28138, Development of a Natural Gas Systems Analysis Model (GSAM). The products developed under this project directly support the National Energy Technology Laboratory (NETL) in carrying out its natural gas R&D mission. The objective of this research effort has been to create a comprehensive, non-proprietary, microcomputer model of the North American natural gas market. GSAM has been developed to explicitly evaluate components of the natural gas system, including the entire in-place gas resource base, exploration and development technologies, extraction technology and performance parameters, transportation and storage factors, and end-use demand issues. The system has been fully tested and calibrated and has been used for multiple natural gas metrics analyses at NETL in which metric associated with NETL natural gas upstream R&D technologies and strategies under the direction of NETL has been evaluated. NETL's Natural Gas Strategic Plan requires that R&D activities be evaluated for their ability to provide adequate supplies of reasonably priced natural gas. GSAM provides the capability to assess potential and on-going R&D projects using a full fuel cycle, cost-benefit approach. This method yields realistic, market-based assessments of benefits and costs of alternative or related technology advances. GSAM is capable of estimating both technical and commercial successes, quantifying the potential benefits to the market, as well as to other related research. GSAM, therefore, represents an integration of research activities and a method for planning and prioritizing efforts to maximize benefits and minimize costs. Without an analytical tool like GSAM, NETL natural gas upstream R&D activities cannot be appropriately ranked or focused on the most important aspects of natural gas extraction efforts or utilization considerations.

  11. Numerical study on modeling of liquid film flow under countercurrent flow limitation in volume of fluid method

    Energy Technology Data Exchange (ETDEWEB)

    Watanabe, Taro, E-mail: watanabe_t@qe.see.eng.osaka-u.ac.jp [Graduate School of Engineering, Osaka University, 2-1, Yamadaoka, Suita-shi, Osaka 565-7895 (Japan); Takata, Takashi, E-mail: takata.takashi@jaea.go.jp [Japan Atomic Energy Agency, 4002 Narita-chou, Oarai-machi, Higashi-Ibaraki-gun, Ibaraki 331-1393 (Japan); Yamaguchi, Akira, E-mail: yamaguchi@n.t.u-tokyo.ac.jp [Graduate School of Engineering, The University of Tokyo, 2-22 Shirakata-Shirane, Tokai-mura, Naka-gun, Ibaraki 319-1188 (Japan)

    2017-03-15

    Highlights: • Thin liquid film flow under CCFL was modeled and coupled with the VOF method. • The difference of the liquid flow rate in experiments of CCFL was evaluated. • The proposed VOF method can quantitatively predict CCFL with low computational cost. - Abstract: Countercurrent flow limitation (CCFL) in a heat transfer tube at a steam generator (SG) of pressurized water reactor (PWR) is one of the important issues on the core cooling under a loss of coolant accident (LOCA). In order to improve the prediction accuracy of the CCFL characteristics in numerical simulations using the volume of fluid (VOF) method with less computational cost, a thin liquid film flow in a countercurrent flow is modeled independently and is coupled with the VOF method. The CCFL characteristics is evaluated analytically in condition of a maximizing down-flow rate as a function of a void fraction or a liquid film thickness considering a critical thickness. Then, we have carried out numerical simulations of a countercurrent flow in a vertical tube so as to investigate the CCFL characteristics and compare them with the previous experimental results. As a result, it has been concluded that the effect of liquid film entrainment by upward gas flux will cause the difference in the experiments.

  12. A data-driven approach for modeling post-fire debris-flow volumes and their uncertainty

    Science.gov (United States)

    Friedel, Michael J.

    2011-01-01

    This study demonstrates the novel application of genetic programming to evolve nonlinear post-fire debris-flow volume equations from variables associated with a data-driven conceptual model of the western United States. The search space is constrained using a multi-component objective function that simultaneously minimizes root-mean squared and unit errors for the evolution of fittest equations. An optimization technique is then used to estimate the limits of nonlinear prediction uncertainty associated with the debris-flow equations. In contrast to a published multiple linear regression three-variable equation, linking basin area with slopes greater or equal to 30 percent, burn severity characterized as area burned moderate plus high, and total storm rainfall, the data-driven approach discovers many nonlinear and several dimensionally consistent equations that are unbiased and have less prediction uncertainty. Of the nonlinear equations, the best performance (lowest prediction uncertainty) is achieved when using three variables: average basin slope, total burned area, and total storm rainfall. Further reduction in uncertainty is possible for the nonlinear equations when dimensional consistency is not a priority and by subsequently applying a gradient solver to the fittest solutions. The data-driven modeling approach can be applied to nonlinear multivariate problems in all fields of study.

  13. Comparison between Local Ensemble Transform Kalman Filter and PSAS in the NASA finite volume GCM – perfect model experiments

    Directory of Open Access Journals (Sweden)

    J. Liu

    2008-08-01

    Full Text Available This paper compares the performance of the Local Ensemble Transform Kalman Filter (LETKF with the Physical-Space Statistical Analysis System (PSAS under a perfect model scenario. PSAS is a 3D-Var assimilation system used operationally in the Goddard Earth Observing System Data Assimilation System (GEOS-4 DAS. The comparison is carried out using simulated winds and geopotential height observations and the finite volume Global Circulation Model with 72 grid points zonally, 46 grid points meridionally and 55 vertical levels. With forty ensemble members, the LETKF obtains analyses and forecasts with significantly lower RMS errors than those from PSAS, especially over the Southern Hemisphere and oceans. This observed advantage of the LETKF over PSAS is due to the ability of the 40-member ensemble LETKF to capture flow-dependent errors and thus create a good estimate of the evolving background uncertainty. An initial decrease of the forecast errors in the Northern Hemisphere observed in the PSAS but not in the LETKF suggests that the LETKF analysis is more balanced.

  14. Control volume analyses of glottal flow using a fully-coupled numerical fluid-structure interaction model

    Science.gov (United States)

    Yang, Jubiao; Krane, Michael; Zhang, Lucy

    2013-11-01

    Vocal fold vibrations and the glottal jet are successfully simulated using the modified Immersed Finite Element method (mIFEM), a fully coupled dynamics approach to model fluid-structure interactions. A self-sustained and steady vocal fold vibration is captured given a constant pressure input at the glottal entrance. The flow rates at different axial locations in the glottis are calculated, showing small variations among them due to the vocal fold motion and deformation. To further facilitate the understanding of the phonation process, two control volume analyses, specifically with Bernoulli's equation and Newton's 2nd law, are carried out for the glottal flow based on the simulation results. A generalized Bernoulli's equation is derived to interpret the correlations between the velocity and pressure temporally and spatially along the center line which is a streamline using a half-space model with symmetry boundary condition. A specialized Newton's 2nd law equation is developed and divided into terms to help understand the driving mechanism of the glottal flow.

  15. A mathematical model for the effects of volume fraction and fiber aspect ratio of biomass mixture during enzymatic hydrolysis

    Science.gov (United States)

    Jamil, Norazaliza Mohd; Wang, Qi

    2017-09-01

    Renewable energy or biofuel from lignocellulosic biomass is an alternative way to replace the depleting fossil fuels. The production cost can be reduced by increasing the concentration of biomass particles. However, lignocellulosic biomass is a suspension of natural fibres, and processing at high solid concentration is a challenging task. Thus, understanding the factors that affect the rheology of biomass suspension is crucial in order to maximize the production at a minimum cost. Our aim was to develop a mathematical model for enzymatic hydrolysis of cellulose by combining three scales: the macroscopic flow field, the mesoscopic particle orientation, and the microscopic reactive kinetics. The governing equations for the flow field, particle stress, kinetic equations, and particle orientation were coupled and were simultaneously solved using a finite element method based software, COMSOL. One of the main results was the changes in rheology of biomass suspension were not only due to the decrease in volume fraction of particles, but also due the types of fibres. The results from the simulation model agreed qualitatively with the experimental findings. This approach has enables us to obtain better predictive capabilities, hence increasing our understanding on the behaviour of biomass suspension.

  16. 3D medical image segmentation based on a continuous modelling of the volume

    International Nuclear Information System (INIS)

    Marque, I.

    1990-12-01

    Several medical imaging/techniques, including Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) provide 3D information of the human body by means of a stack of parallel cross-sectional images. But a more sophisticated edge detection step has to be performed when the object under study is not well defined by its characteristic density or when an analytical knowledge of the surface of the object is useful for later processings. A new method for medical image segmentation has been developed: it uses the stability and differentiability properties of a continuous modelling of the 3D data. The idea is to build a system of Ordinary Differential Equations which the stable manifold is the surface of the object we are looking for. This technique has been applied to classical edge detection operators: threshold following, laplacian, gradient maximum in its direction. It can be used in 2D as well as in 3D and has been extended to seek particular points of the surface, such as local extrema. The major advantages of this method are as follows: the segmentation and boundary following steps are performed simultaneously, an analytical representation of the surface is obtained straightforwardly and complex objects in which branching problems may occur can be described automatically. Simulations on noisy synthetic images have induced a quantization step to test the sensitiveness to noise of our method with respect to each operator, and to study the influence of all the parameters. Last, this method has been applied to numerous real clinical exams: skull or femur images provided by CT, MR images of a cerebral tumor and of the ventricular system. These results show the reliability and the efficiency of this new method of segmentation [fr

  17. Alligator Rivers Analogue project. Geochemical modelling of present-day groundwaters. Final Report - Volume 12

    International Nuclear Information System (INIS)

    Sverjensky, D. A.

    1992-01-01

    The main purpose of this report is to summarize geochemical modeling studies of the present-day Koongarra groundwaters. Information on the present-day geochemistry and geochemical processes at Koongarra forms a basis for a present-day analogue for nuclear waste migration. The present-day analogue is built on studies of the mineralogy and petrology of the Koongarra deposit, and chemical analyses of present-day groundwaters from the deposit. The overall approach taken in the present study has been to carry out a series of aqueous speciation and state of saturation calculations, including chemical mass transfer calculations, to address the possible control over the chemistry of the present-day for the groundwaters at Koongarra. The most important implication of the present study for the migration of radionuclides is the strong role played by the water-rock interactions, both above and below the water table, influencing the overall chemical evolution of the groundwaters. Thus, the results show that the chemical evolution of waters is strongly controlled by the initial availability of CO 2 and the mineral assemblage encountered, which together determine the major element evolution of the waters by controlling the pH. The relative rates of evolution of the pH and the oxidation state of the groundwaters are also critical to the mobility of uranium. The shallow Koongarra waters are sufficiently oxidising that they can dissolve and transport uranium even under acidic conditions. Under the more reducing condition of the deep groundwaters, is the pH level that permits uranium transport as carbonate complexes. However, if the oxidation state decreases to much lower levels, it would be expected that uranium become immobile. All the speciation and state of saturation calculations carried out in the present study are available from the author, on request

  18. Four-chamber heart modeling and automatic segmentation for 3-D cardiac CT volumes using marginal space learning and steerable features.

    Science.gov (United States)

    Zheng, Yefeng; Barbu, Adrian; Georgescu, Bogdan; Scheuering, Michael; Comaniciu, Dorin

    2008-11-01

    We propose an automatic four-chamber heart segmentation system for the quantitative functional analysis of the heart from cardiac computed tomography (CT) volumes. Two topics are discussed: heart modeling and automatic model fitting to an unseen volume. Heart modeling is a nontrivial task since the heart is a complex nonrigid organ. The model must be anatomically accurate, allow manual editing, and provide sufficient information to guide automatic detection and segmentation. Unlike previous work, we explicitly represent important landmarks (such as the valves and the ventricular septum cusps) among the control points of the model. The control points can be detected reliably to guide the automatic model fitting process. Using this model, we develop an efficient and robust approach for automatic heart chamber segmentation in 3-D CT volumes. We formulate the segmentation as a two-step learning problem: anatomical structure localization and boundary delineation. In both steps, we exploit the recent advances in learning discriminative models. A novel algorithm, marginal space learning (MSL), is introduced to solve the 9-D similarity transformation search problem for localizing the heart chambers. After determining the pose of the heart chambers, we estimate the 3-D shape through learning-based boundary delineation. The proposed method has been extensively tested on the largest dataset (with 323 volumes from 137 patients) ever reported in the literature. To the best of our knowledge, our system is the fastest with a speed of 4.0 s per volume (on a dual-core 3.2-GHz processor) for the automatic segmentation of all four chambers.

  19. Parametric exergy analysis of a tubular Solid Oxide Fuel Cell (SOFC) stack through finite-volume model

    International Nuclear Information System (INIS)

    Calise, F.; Ferruzzi, G.; Vanoli, L.

    2009-01-01

    This paper presents a very detailed local exergy analysis of a tubular Solid Oxide Fuel Cell (SOFC) stack. In particular, a complete parametric analysis has been carried out, in order to assess the effects of the synthesis/design parameters on the local irreversibilities in the components of the stack. A finite-volume axial-symmetric model of the tubular internal reforming Solid Oxide Fuel Cell stack under investigation has been used. The stack consists of: SOFC tubes, tube-in-tube pre-reformer and tube and shell catalytic burner. The model takes into account the effects of heat/mass transfer and chemical/electrochemical reactions. The model allows one to predict the performance of a SOFC stack once a series of design and operative parameters are fixed, but also to investigate the source and localization of inefficiency. To this scope, an exergy analysis was implemented. The SOFC tube, the pre-reformer and the catalytic burner are discretized along their longitudinal axes. Detailed models of the kinetics of the reforming, catalytic combustion and electrochemical reactions are implemented. Pressure drops, convection heat transfer and overvoltages are calculated on the basis of the work previously developed by the authors. The heat transfer model includes the contribution of thermal radiation, so improving the models previously used by the authors. Radiative heat transfer is calculated on the basis of the slice-to-slice configuration factors and corresponding radiosities. On the basis of this thermochemical model, an exergy analysis has been carried out, in order to localize the sources and the magnitude of irreversibilities along the components of the stack. In addition, the main synthesis/design variables were varied in order to assess their effect on the exergy destruction within the component to which the parameter directly refers ('endogenous' contribution) and on the exergy destruction of all remaining components ('exogenous' contribution). Then, this analysis

  20. An assessment of uncertainties in using volume-area modelling for computing the twenty-first century glacier contribution to sea-level change

    Directory of Open Access Journals (Sweden)

    A. B. A. Slangen

    2011-08-01

    Full Text Available A large part of present-day sea-level change is formed by the melt of glaciers and ice caps (GIC. This study focuses on the uncertainties in the calculation of the GIC contribution on a century timescale. The model used is based on volume-area scaling, combined with the mass balance sensitivity of the GIC. We assess different aspects that contribute to the uncertainty in the prediction of the contribution of GIC to future sea-level rise, such as (1 the volume-area scaling method (scaling factor, (2 the glacier data, (3 the climate models, and (4 the emission scenario. Additionally, a comparison of the model results to the 20th century GIC contribution is presented.

    We find that small variations in the scaling factor cause significant variations in the initial volume of the glaciers, but only limited variations in the glacier volume change. If two existing glacier inventories are tuned such that the initial volume is the same, the GIC sea-level contribution over 100 yr differs by 0.027 m or 18 %. It appears that the mass balance sensitivity is also important: variations of 20 % in the mass balance sensitivity have an impact of 17 % on the resulting sea-level projections. Another important factor is the choice of the climate model, as the GIC contribution to sea-level change largely depends on the temperature and precipitation taken from climate models. Connected to this is the choice of emission scenario, used to drive the climate models. Combining all the uncertainties examined in this study leads to a total uncertainty of 0.052 m or 35 % in the GIC contribution to global mean sea level. Reducing the variance in the climate models and improving the glacier inventories will significantly reduce the uncertainty in calculating the GIC contributions, and are therefore crucial actions to improve future sea-level projections.

  1. Industrial Sector Technology Use Model (ISTUM): industrial energy use in the United States, 1974-2000. Volume 4. Technology appendix. Final Report

    Energy Technology Data Exchange (ETDEWEB)

    1979-10-01

    Volume IV of the ISTUM documentation gives information on the individual technology specifications, but relates closely with Chapter II of Volume I. The emphasis in that chapter is on providing an overview of where each technology fits into the general-model logic. Volume IV presents the actual cost structure and specification of every technology modeled in ISTUM. The first chapter presents a general overview of the ISTUM technology data base. It includes an explanation of the data base printouts and how the separate-cost building blocks are combined to derive an aggregate-technology cost. The remaining chapters are devoted to documenting the specific-technology cost specifications. Technologies included are: conventional technologies (boiler and non-boiler conventional technologies); fossil-energy technologies (atmospheric fluidized bed combustion, low Btu coal and medium Btu coal gasification); cogeneration (steam, machine drive, and electrolytic service sectors); and solar and geothermal technologies (solar steam, solar space heat, and geothermal steam technologies), and conservation technologies.

  2. CoMiniGut—a small volume in vitro colon model for the screening of gut microbial fermentation processes

    Directory of Open Access Journals (Sweden)

    Maria Wiese

    2018-01-01

    Full Text Available Driven by the growing recognition of the influence of the gut microbiota (GM on human health and disease, there is a rapidly increasing interest in understanding how dietary components, pharmaceuticals and pre- and probiotics influence GM. In vitro colon models represent an attractive tool for this purpose. With the dual objective of facilitating the investigation of rare and expensive compounds, as well as an increased throughput, we have developed a prototype in vitro parallel gut microbial fermentation screening tool with a working volume of only 5 ml consisting of five parallel reactor units that can be expanded with multiples of five to increase throughput. This allows e.g., the investigation of interpersonal variations in gut microbial dynamics and the acquisition of larger data sets with enhanced statistical inference. The functionality of the in vitro colon model, Copenhagen MiniGut (CoMiniGut was first demonstrated in experiments with two common prebiotics using the oligosaccharide inulin and the disaccharide lactulose at 1% (w/v. We then investigated fermentation of the scarce and expensive human milk oligosaccharides (HMOs 3-Fucosyllactose, 3-Sialyllactose, 6-Sialyllactose and the more common Fructooligosaccharide in fermentations with infant gut microbial communities. Investigations of microbial community composition dynamics in the CoMiniGut reactors by MiSeq-based 16S rRNA gene amplicon high throughput sequencing showed excellent experimental reproducibility and allowed us to extract significant differences in gut microbial composition after 24 h of fermentation for all investigated substrates and fecal donors. Furthermore, short chain fatty acids (SCFAs were quantified for all treatments and donors. Fermentations with inulin and lactulose showed that inulin leads to a microbiota dominated by obligate anaerobes, with high relative abundance of Bacteroidetes, while the more easily fermented lactulose leads to higher relative

  3. CoMiniGut—a small volume in vitro colon model for the screening of gut microbial fermentation processes

    Science.gov (United States)

    Khakimov, Bekzod; Nielsen, Sebastian; Sørensen, Helena; van den Berg, Frans; Nielsen, Dennis Sandris

    2018-01-01

    Driven by the growing recognition of the influence of the gut microbiota (GM) on human health and disease, there is a rapidly increasing interest in understanding how dietary components, pharmaceuticals and pre- and probiotics influence GM. In vitro colon models represent an attractive tool for this purpose. With the dual objective of facilitating the investigation of rare and expensive compounds, as well as an increased throughput, we have developed a prototype in vitro parallel gut microbial fermentation screening tool with a working volume of only 5 ml consisting of five parallel reactor units that can be expanded with multiples of five to increase throughput. This allows e.g., the investigation of interpersonal variations in gut microbial dynamics and the acquisition of larger data sets with enhanced statistical inference. The functionality of the in vitro colon model, Copenhagen MiniGut (CoMiniGut) was first demonstrated in experiments with two common prebiotics using the oligosaccharide inulin and the disaccharide lactulose at 1% (w/v). We then investigated fermentation of the scarce and expensive human milk oligosaccharides (HMOs) 3-Fucosyllactose, 3-Sialyllactose, 6-Sialyllactose and the more common Fructooligosaccharide in fermentations with infant gut microbial communities. Investigations of microbial community composition dynamics in the CoMiniGut reactors by MiSeq-based 16S rRNA gene amplicon high throughput sequencing showed excellent experimental reproducibility and allowed us to extract significant differences in gut microbial composition after 24 h of fermentation for all investigated substrates and fecal donors. Furthermore, short chain fatty acids (SCFAs) were quantified for all treatments and donors. Fermentations with inulin and lactulose showed that inulin leads to a microbiota dominated by obligate anaerobes, with high relative abundance of Bacteroidetes, while the more easily fermented lactulose leads to higher relative abundance of

  4. CoMiniGut-a small volume in vitro colon model for the screening of gut microbial fermentation processes.

    Science.gov (United States)

    Wiese, Maria; Khakimov, Bekzod; Nielsen, Sebastian; Sørensen, Helena; van den Berg, Frans; Nielsen, Dennis Sandris

    2018-01-01

    Driven by the growing recognition of the influence of the gut microbiota (GM) on human health and disease, there is a rapidly increasing interest in understanding how dietary components, pharmaceuticals and pre- and probiotics influence GM. In vitro colon models represent an attractive tool for this purpose. With the dual objective of facilitating the investigation of rare and expensive compounds, as well as an increased throughput, we have developed a prototype in vitro parallel gut microbial fermentation screening tool with a working volume of only 5 ml consisting of five parallel reactor units that can be expanded with multiples of five to increase throughput. This allows e.g., the investigation of interpersonal variations in gut microbial dynamics and the acquisition of larger data sets with enhanced statistical inference. The functionality of the in vitro colon model, Copenhagen MiniGut (CoMiniGut) was first demonstrated in experiments with two common prebiotics using the oligosaccharide inulin and the disaccharide lactulose at 1% (w/v). We then investigated fermentation of the scarce and expensive human milk oligosaccharides (HMOs) 3-Fucosyllactose, 3-Sialyllactose, 6-Sialyllactose and the more common Fructooligosaccharide in fermentations with infant gut microbial communities. Investigations of microbial community composition dynamics in the CoMiniGut reactors by MiSeq-based 16S rRNA gene amplicon high throughput sequencing showed excellent experimental reproducibility and allowed us to extract significant differences in gut microbial composition after 24 h of fermentation for all investigated substrates and fecal donors. Furthermore, short chain fatty acids (SCFAs) were quantified for all treatments and donors. Fermentations with inulin and lactulose showed that inulin leads to a microbiota dominated by obligate anaerobes, with high relative abundance of Bacteroidetes, while the more easily fermented lactulose leads to higher relative abundance of

  5. Sex differences in cell genesis, hippocampal volume and behavioral outcomes in a rat model of neonatal HI.

    Science.gov (United States)

    Waddell, Jaylyn; Hanscom, Marie; Shalon Edwards, N; McKenna, Mary C; McCarthy, Margaret M

    2016-01-01

    Hypoxia-ischemia (HI) of the brain in near-term and term infants is a leading cause of infant mortality and lifelong disability but current therapeutic approaches remain limited. Males consistently display greater vulnerability to the deleterious consequences of HI in both humans and animal models. Neurogenesis increases after neonatal HI and offers a potential therapeutic target for recovery. The steroid hormone estradiol has been extensively explored as a neuroprotectant in adult models of stroke but with mixed results. Less consideration has been afforded to this naturally occurring agent in the developing brain, which has unique challenges from the adult. Using a model of term HI in the rat we have explored the impact of this insult on cell genesis in the hippocampus of males and females and the ability of estradiol treatment immediately after insult to restore function. Both short-term (3 days) and long-term (7 days) post-injury were assessed and revealed that only females had markedly increased cell genesis on the short-term but both sexes were increased long-term. A battery of behavioral tests revealed motor impairment in males and compromised episodic memory while both sexes were modestly impaired in spatial memory. Juvenile social play was also depressed in both sexes after HI. Estradiol therapy improved behavioral performance in both sexes but did not reverse a deficit in hippocampal volume ipsilateral to the insult. Thus the effects of estradiol do not appear to be via cell death or proliferation but rather involve other components of neural functioning. Published by Elsevier Inc.

  6. A multi-scale cardiovascular system model can account for the load-dependence of the end-systolic pressure-volume relationship

    Science.gov (United States)

    2013-01-01

    Background The end-systolic pressure-volume relationship is often considered as a load-independent property of the heart and, for this reason, is widely used as an index of ventricular contractility. However, many criticisms have been expressed against this index and the underlying time-varying elastance theory: first, it does not consider the phenomena underlying contraction and second, the end-systolic pressure volume relationship has been experimentally shown to be load-dependent. Methods In place of the time-varying elastance theory, a microscopic model of sarcomere contraction is used to infer the pressure generated by the contraction of the left ventricle, considered as a spherical assembling of sarcomere units. The left ventricle model is inserted into a closed-loop model of the cardiovascular system. Finally, parameters of the modified cardiovascular system model are identified to reproduce the hemodynamics of a normal dog. Results Experiments that have proven the limitations of the time-varying elastance theory are reproduced with our model: (1) preload reductions, (2) afterload increases, (3) the same experiments with increased ventricular contractility, (4) isovolumic contractions and (5) flow-clamps. All experiments simulated with the model generate different end-systolic pressure-volume relationships, showing that this relationship is actually load-dependent. Furthermore, we show that the results of our simulations are in good agreement with experiments. Conclusions We implemented a multi-scale model of the cardiovascular system, in which ventricular contraction is described by a detailed sarcomere model. Using this model, we successfully reproduced a number of experiments that have shown the failing points of the time-varying elastance theory. In particular, the developed multi-scale model of the cardiovascular system can capture the load-dependence of the end-systolic pressure-volume relationship. PMID:23363818

  7. Lung volume quantified by MRI reflects extracellular-matrix deposition and altered pulmonary function in bleomycin models of fibrosis: effects of SOM230.

    Science.gov (United States)

    Egger, Christine; Gérard, Christelle; Vidotto, Nella; Accart, Nathalie; Cannet, Catherine; Dunbar, Andrew; Tigani, Bruno; Piaia, Alessandro; Jarai, Gabor; Jarman, Elizabeth; Schmid, Herbert A; Beckmann, Nicolau

    2014-06-15

    Idiopathic pulmonary fibrosis is a progressive and lethal disease, characterized by loss of lung elasticity and alveolar surface area, secondary to alveolar epithelial cell injury, reactive inflammation, proliferation of fibroblasts, and deposition of extracellular matrix. The effects of oropharyngeal aspiration of bleomycin in Sprague-Dawley rats and C57BL/6 mice, as well as of intratracheal administration of ovalbumin to actively sensitized Brown Norway rats on total lung volume as assessed noninvasively by magnetic resonance imaging (MRI) were investigated here. Lung injury and volume were quantified by using nongated or respiratory-gated MRI acquisitions [ultrashort echo time (UTE) or gradient-echo techniques]. Lung function of bleomycin-challenged rats was examined additionally using a flexiVent system. Postmortem analyses included histology of collagen and hydroxyproline assays. Bleomycin induced an increase of MRI-assessed total lung volume, lung dry and wet weights, and hydroxyproline content as well as collagen amount. In bleomycin-treated rats, gated MRI showed an increased volume of the lung in the inspiratory and expiratory phases of the respiratory cycle and a temporary decrease of tidal volume. Decreased dynamic lung compliance was found in bleomycin-challenged rats. Bleomycin-induced increase of MRI-detected lung volume was consistent with tissue deposition during fibrotic processes resulting in decreased lung elasticity, whereas influences by edema or emphysema could be excluded. In ovalbumin-challenged rats, total lung volume quantified by MRI remained unchanged. The somatostatin analog, SOM230, was shown to have therapeutic effects on established bleomycin-induced fibrosis in rats. This work suggests MRI-detected total lung volume as readout for tissue-deposition in small rodent bleomycin models of pulmonary fibrosis. Copyright © 2014 the American Physiological Society.

  8. External validation of a forest inventory and analysis volume equation and comparisons with estimates from multiple stem-profile models

    Science.gov (United States)

    Christopher M. Oswalt; Adam M. Saunders

    2009-01-01

    Sound estimation procedures are desideratum for generating credible population estimates to evaluate the status and trends in resource conditions. As such, volume estimation is an integral component of the U.S. Department of Agriculture, Forest Service, Forest Inventory and Analysis (FIA) program's reporting. In effect, reliable volume estimation procedures are...

  9. First experiences with model based iterative reconstructions influence on quantitative plaque volume and intensity measurements in coronary computed tomography angiography

    DEFF Research Database (Denmark)

    Precht, Helle; Kitslaar, Pieter H.; Broersen, Alexander

    2017-01-01

    : Three patients had three independent dose reduced CCTA performed and reconstructed with 30% ASIR (CTDIvol at 6.7 mGy), 60% ASIR (CTDIvol 4.3 mGy) and Veo (CTDIvol at 1.9 mGy). Coronary plaque analysis was performed for each measured CCTA volumes, plaque burden and intensities. Results: Plaque volume...

  10. Very low tidal volume ventilation with associated hypercapnia--effects on lung injury in a model for acute respiratory distress syndrome.

    Directory of Open Access Journals (Sweden)

    Hans Fuchs

    Full Text Available BACKGROUND: Ventilation using low tidal volumes with permission of hypercapnia is recommended to protect the lung in acute respiratory distress syndrome. However, the most lung protective tidal volume in association with hypercapnia is unknown. The aim of this study was to assess the effects of different tidal volumes with associated hypercapnia on lung injury and gas exchange in a model for acute respiratory distress syndrome. METHODOLOGY/PRINCIPAL FINDINGS: In this randomized controlled experiment sixty-four surfactant-depleted rabbits were exposed to 6 hours of mechanical ventilation with the following targets: Group 1: tidal volume = 8-10 ml/kg/PaCO(2 = 40 mm Hg; Group 2: tidal volume = 4-5 ml/kg/PaCO(2 = 80 mm Hg; Group 3: tidal volume = 3-4 ml/kg/PaCO(2 = 120 mm Hg; Group 4: tidal volume = 2-3 ml/kg/PaCO(2 = 160 mm Hg. Decreased wet-dry weight ratios of the lungs, lower histological lung injury scores and higher PaO(2 were found in all low tidal volume/hypercapnia groups (group 2, 3, 4 as compared to the group with conventional tidal volume/normocapnia (group 1. The reduction of the tidal volume below 4-5 ml/kg did not enhance lung protection. However, oxygenation and lung protection were maintained at extremely low tidal volumes in association with very severe hypercapnia and no adverse hemodynamic effects were observed with this strategy. CONCLUSION: Ventilation with low tidal volumes and associated hypercapnia was lung protective. A tidal volume below 4-5 ml/kg/PaCO(2 80 mm Hg with concomitant more severe hypercapnic acidosis did not increase lung protection in this surfactant deficiency model. However, even at extremely low tidal volumes in association with severe hypercapnia lung protection and oxygenation were maintained.

  11. Determining the Hydrologic Impacts of Climate Variability on Florida's Everglades Through the Use of a Finite Volume Hydrologic Model

    Science.gov (United States)

    Senarath, S. U.; Novoa, R. J.; Niedzialek, J. M.; Zheng, F.

    2006-12-01

    A good understanding of climate variability and its impacts on the regional water budget are crucial for the restoration of Florida's Everglades. This is investigated by varying the two most sensitive climatic data sets, namely rainfall and evapotranspiration of a regional-scale hydrologic model. A 36-year long record, spanning from 1965 to 2000 is used in these assessments. Although not comprehensive, these data sets include several seasons with extremely high and low rainfall and evapotranspiration. The Everglades National Park, the Big Cypress National Preserve, and the Water Conservation Areas 3A and 3B are included in the study area. These watersheds jointly encompass an area of 10,158 square kilometers, and are home to many endangered and threatened species of fauna and flora. The Regional Simulation Model (RSM) developed by the South Florida Water Management District (SFWMD) is used in this study to evaluate and quantify the hydrologic responses caused due to climate variability. RSM is a finite-volume, regional-scale, distributed, continuous hydrologic model with fully coupled groundwater, canal and overland flow components. This model uses a variable triangular mesh that conforms to levees, canals and sub-basin boundaries. RSM can adequately simulate the low-relief topography, and high water tables, saturated hydraulic conductivities and surface roughnesses that exist in Florida's Everglades. The model uses the diffusive wave approximation of Saint-Venant's equation to simulate canal and overland flows. The Southern Everglades implementation of the RSM (hereafter, Southern Everglades Model or SEM) is calibrated and verified using stage data from 1988 to 1995, and 1996 to 2000, respectively. An irregular triangular mesh with 52,817 cells and a one-day time step are used in this implementation. For all simulations and assessments the model boundary conditions are obtained from the South Florida Water Management Model developed by the SFWMD. Two types of

  12. Modeling of development and projection of the accumulated recoverable oil volume: methodology and application; Modelagem da evolucao e projecao de volume de oleo recuperavel acumulado: metodologia e aplicacao

    Energy Technology Data Exchange (ETDEWEB)

    Melo, Luciana Cavalcanti de; Ferreira Filho, Virgilio Jose Martins; Rocha, Vinicius Brito [Universidade Federal do Rio de Janeiro (UFRJ), RJ (Brazil). Coordenacao dos Programas de Pos-graduacao de Engenharia (COPPE)

    2004-07-01

    A relevant problem that petroleum companies deal is the estimate of the future levels of reserves The objective of the reserve forecasting is pursued through the construction of mathematical models. Considering that the exploration process is an informed and controlled process, in order to reach the exploration targets, the exploration process is lead inside of a sequence of decisions based on the reached results. Such decisions are taken surrounded by an uncertain environment added to the random nature of the process. Another important assumption that must be taken into consideration is the dependency of the exploration on the conditions, or structure, of the discovered resources and the final potential. The modeling starts with the establishment of a general problem, when the models are being constructed, based on suppositions associated to the main concepts, and ends with the attainment of specific solutions, when the best description, or model, is selected through the estimate of the respective parameters and of the measurement adjustments. The result of this approach reflects the essence of the exploration process and how it is reflected in the incorporation of reserves and history of field discoveries. A case study is used for validation of the models and the estimates. (author)

  13. MODEL SISTIM INFORMASI GEOGRAFIS UNTUK ESTIMASI VOLUME ALIRAN DAN EROSI SEDIMEN DI DAS RIAM KANAN PROVINSI KALIMANTAN SELATAN (GEOGRAPHIC INFORMATION SYSTEM MODEL TO ESTIMATE FOR DEBIT OF RIAM KANAN WATERSHED IN KALIMANTAN SELATAN

    Directory of Open Access Journals (Sweden)

    Abdur Rahman

    2016-06-01

    Full Text Available Dalam penentuan estimasi volume aliran, diperlukan model yang tepat yang dapat memperkirakan nilai volume aliran suatu DAS.  Telah terjadi penurunan daya dukung Sub DAS Riam Kanan sebagai daerah tangkapan air yang disebabkan oleh kritisnya tutupan lahan.  Penelitian ini bertujuan untuk estimasi volume aliran dan distribusinya di DAS Riam Kanan dan Sekitarnya berdasarkan data Citra Satelit Landsat7 ETM+. Hasil penelitian menghasilkan persamaan regresi Qp = 0,007p + 56,85 dengan tingkat regresi sebesar 89,6 %, menunjukkan bahwa tutupan lahan dapat berakibat langsung terhadap perubahan volume aliran di sub DAS Riam Kanan dan sekitarnya.   Dengan menggunakan data volume aliran yang tercatat pada papan duga muka air waduk (DMA dan data hujan penyebabnya, diperoleh data volume aliran terendah di Daerah Rantau Balai yaitu sebesar 2,14 m3/det dan tertinggi di daerah Rantau Bujur sebesar 17,65 m3/det.  Sedangkan untuk daerah-daerah Bunglai, Tiwingan, Kalaan dan Belangian mempunyai volume aliran sedang berkisar antara 2,16 m3/det – 6,59 m3/det. In determining the estimated volume flow, required an appropriate model to estimate the value of the volume flow of a watershed. It has been a decline in the carrying capacity of the Sub Watershed of Riam Kanan as the catchment area due to critical land cover. This study aims to estimate the flow of volume and its distribution in the Riam Kanan Watershed  based on data Landsat7 ETM + Satellite Imagery. The results yield a regression equation Qp = 0.007p + 56.85 regression rate of 89.6%, indicating that land cover can lead directly to changes in flow volume in the sub watershed of Riam Kanan By using the data flow volume recorded on board thought the water reservoir (DMA and data rains cause, the lowest flow volume data obtained in the lowest in Rantau Balai amount of 2.14 m3/sec and the highest in  the  Rantau  Bujur amount of 17.65 m3/sec. As for the areas Bunglai, Tiwingan, Kalaan and Belangian have

  14. Pairwise mixture model for unmixing partial volume effect in multi-voxel MR spectroscopy of brain tumour patients

    Science.gov (United States)

    Olliverre, Nathan; Asad, Muhammad; Yang, Guang; Howe, Franklyn; Slabaugh, Gregory

    2017-03-01

    Multi-Voxel Magnetic Resonance Spectroscopy (MV-MRS) provides an important and insightful technique for the examination of the chemical composition of brain tissue, making it an attractive medical imaging modality for the examination of brain tumours. MRS, however, is affected by the issue of the Partial Volume Effect (PVE), where the signals of multiple tissue types can be found within a single voxel and provides an obstacle to the interpretation of the data. The PVE results from the low resolution achieved in MV-MRS images relating to the signal to noise ratio (SNR). To counteract PVE, this paper proposes a novel Pairwise Mixture Model (PMM), that extends a recently reported Signal Mixture Model (SMM) for representing the MV-MRS signal as normal, low or high grade tissue types. Inspired by Conditional Random Field (CRF) and its continuous variant the PMM incorporates the surrounding voxel neighbourhood into an optimisation problem, the solution of which provides an estimation to a set of coefficients. The values of the estimated coefficients represents the amount of each tissue type (normal, low or high) found within a voxel. These coefficients can then be visualised as a nosological rendering using a coloured grid representing the MV-MRS image overlaid on top of a structural image, such as a Magnetic Resonance Image (MRI). Experimental results show an accuracy of 92.69% in classifying patient tumours as either low or high grade compared against the histopathology for each patient. Compared to 91.96% achieved by the SMM, the proposed PMM method demonstrates the importance of incorporating spatial coherence into the estimation as well as its potential clinical usage.

  15. Combining EEG and MEG for the reconstruction of epileptic activity using a calibrated realistic volume conductor model.

    Directory of Open Access Journals (Sweden)

    Ümit Aydin

    Full Text Available To increase the reliability for the non-invasive determination of the irritative zone in presurgical epilepsy diagnosis, we introduce here a new experimental and methodological source analysis pipeline that combines the complementary information in EEG and MEG, and apply it to data from a patient, suffering from refractory focal epilepsy. Skull conductivity parameters in a six compartment finite element head model with brain anisotropy, constructed from individual MRI data, are estimated in a calibration procedure using somatosensory evoked potential (SEP and field (SEF data. These data are measured in a single run before acquisition of further runs of spontaneous epileptic activity. Our results show that even for single interictal spikes, volume conduction effects dominate over noise and need to be taken into account for accurate source analysis. While cerebrospinal fluid and brain anisotropy influence both modalities, only EEG is sensitive to skull conductivity and conductivity calibration significantly reduces the difference in especially depth localization of both modalities, emphasizing its importance for combining EEG and MEG source analysis. On the other hand, localization differences which are due to the distinct sensitivity profiles of EEG and MEG persist. In case of a moderate error in skull conductivity, combined source analysis results can still profit from the different sensitivity profiles of EEG and MEG to accurately determine location, orientation and strength of the underlying sources. On the other side, significant errors in skull modeling are reflected in EEG reconstruction errors and could reduce the goodness of fit to combined datasets. For combined EEG and MEG source analysis, we therefore recommend calibrating skull conductivity using additionally acquired SEP/SEF data.

  16. Combining EEG and MEG for the reconstruction of epileptic activity using a calibrated realistic volume conductor model.

    Science.gov (United States)

    Aydin, Ümit; Vorwerk, Johannes; Küpper, Philipp; Heers, Marcel; Kugel, Harald; Galka, Andreas; Hamid, Laith; Wellmer, Jörg; Kellinghaus, Christoph; Rampp, Stefan; Wolters, Carsten Hermann

    2014-01-01

    To increase the reliability for the non-invasive determination of the irritative zone in presurgical epilepsy diagnosis, we introduce here a new experimental and methodological source analysis pipeline that combines the complementary information in EEG and MEG, and apply it to data from a patient, suffering from refractory focal epilepsy. Skull conductivity parameters in a six compartment finite element head model with brain anisotropy, constructed from individual MRI data, are estimated in a calibration procedure using somatosensory evoked potential (SEP) and field (SEF) data. These data are measured in a single run before acquisition of further runs of spontaneous epileptic activity. Our results show that even for single interictal spikes, volume conduction effects dominate over noise and need to be taken into account for accurate source analysis. While cerebrospinal fluid and brain anisotropy influence both modalities, only EEG is sensitive to skull conductivity and conductivity calibration significantly reduces the difference in especially depth localization of both modalities, emphasizing its importance for combining EEG and MEG source analysis. On the other hand, localization differences which are due to the distinct sensitivity profiles of EEG and MEG persist. In case of a moderate error in skull conductivity, combined source analysis results can still profit from the different sensitivity profiles of EEG and MEG to accurately determine location, orientation and strength of the underlying sources. On the other side, significant errors in skull modeling are reflected in EEG reconstruction errors and could reduce the goodness of fit to combined datasets. For combined EEG and MEG source analysis, we therefore recommend calibrating skull conductivity using additionally acquired SEP/SEF data.

  17. Myocardial twitch duration and the dependence of oxygen consumption on pressure-volume area: experiments and modelling.

    Science.gov (United States)

    Han, J-C; Tran, K; Taberner, A J; Nickerson, D P; Kirton, R S; Nielsen, P M F; Ward, M-L; Nash, M P; Crampin, E J; Loiselle, D S

    2012-09-15

    We tested the proposition that linear length dependence of twitch duration underlies the well-characterised linear dependence of oxygen consumption (V(O(2)) ) on pressure–volume area (PVA) in the heart. By way of experimental simplification, we reduced the problem from three dimensions to one by substituting cardiac trabeculae for the classically investigated whole-heart. This allowed adoption of stress–length area (SLA) as a surrogate for PVA, and heat as a proxy for V(O(2)) . Heat and stress (force per cross-sectional area), at a range of muscle lengths and at both 1 mM and 2 mM [Ca(2+)](o), were recorded from continuously superfused rat right-ventricular trabeculae undergoing fixed-end contractions. The heat–SLA relations of trabeculae (reported here, for the first time) are linear. Twitch duration increases monotonically (but not strictly linearly) with muscle length. We probed the cellular mechanisms of this phenomenon by determining: (i) the length dependence of the duration of the Ca(2+) transient, (ii) the length dependence of the rate of force redevelopment following a length impulse (an index of Ca(2+) binding to troponin-C), (iii) the effect on the simulated time course of the twitch of progressive deletion of length and Ca(2+)-dependent mechanisms of crossbridge cooperativity, using a detailed mathematical model of the crossbridge cycle, and (iv) the conditions required to achieve these multiple length dependencies, using a greatly simplified model of twitch mechano-energetics. From the results of these four independent investigations, we infer that the linearity of the heat–SLA relation (and, by analogy, the V(O(2))–PVA relation) is remarkably robust in the face of departures from linearity of length-dependent twitch duration.

  18. Myocardial twitch duration and the dependence of oxygen consumption on pressure–volume area: experiments and modelling

    Science.gov (United States)

    Han, J-C; Tran, K; Taberner, A J; Nickerson, D P; Kirton, R S; Nielsen, P M F; Ward, M-L; Nash, M P; Crampin, E J; Loiselle, D S

    2012-01-01

    We tested the proposition that linear length dependence of twitch duration underlies the well-characterised linear dependence of oxygen consumption () on pressure–volume area (PVA) in the heart. By way of experimental simplification, we reduced the problem from three dimensions to one by substituting cardiac trabeculae for the classically investigated whole-heart. This allowed adoption of stress–length area (SLA) as a surrogate for PVA, and heat as a proxy for . Heat and stress (force per cross-sectional area), at a range of muscle lengths and at both 1 mm and 2 mm[Ca2+]o, were recorded from continuously superfused rat right-ventricular trabeculae undergoing fixed-end contractions. The heat–SLA relations of trabeculae (reported here, for the first time) are linear. Twitch duration increases monotonically (but not strictly linearly) with muscle length. We probed the cellular mechanisms of this phenomenon by determining: (i) the length dependence of the duration of the Ca2+ transient, (ii) the length dependence of the rate of force redevelopment following a length impulse (an index of Ca2+ binding to troponin-C), (iii) the effect on the simulated time course of the twitch of progressive deletion of length- and Ca2+-dependent mechanisms of crossbridge cooperativity, using a detailed mathematical model of the crossbridge cycle, and (iv) the conditions required to achieve these multiple length dependencies, using a greatly simplified model of twitch mechano-energetics. From the results of these four independent investigations, we infer that the linearity of the heat–SLA relation (and, by analogy, the –PVA relation) is remarkably robust in the face of departures from linearity of length-dependent twitch duration. PMID:22570375

  19. Closing the loop: modelling of heart failure progression from health to end-stage using a meta-analysis of left ventricular pressure-volume loops.

    Science.gov (United States)

    Warriner, David R; Brown, Alistair G; Varma, Susheel; Sheridan, Paul J; Lawford, Patricia; Hose, David R; Al-Mohammad, Abdallah; Shi, Yubing

    2014-01-01

    The American Heart Association (AHA)/American College of Cardiology (ACC) guidelines for the classification of heart failure (HF) are descriptive but lack precise and objective measures which would assist in categorising such patients. Our aim was two fold, firstly to demonstrate quantitatively the progression of HF through each stage using a meta-analysis of existing left ventricular (LV) pressure-volume (PV) loop data and secondly use the LV PV loop data to create stage specific HF models. A literature search yielded 31 papers with PV data, representing over 200 patients in different stages of HF. The raw pressure and volume data were extracted from the papers using a digitising software package and the means were calculated. The data demonstrated that, as HF progressed, stroke volume (SV), ejection fraction (EF%) decreased while LV volumes increased. A 2-element lumped parameter model was employed to model the mean loops and the error was calculated between the loops, demonstrating close fit between the loops. The only parameter that was consistently and statistically different across all the stages was the elastance (Emax). For the first time, the authors have created a visual and quantitative representation of the AHA/ACC stages of LVSD-HF, from normal to end-stage. The study demonstrates that robust, load-independent and reproducible parameters, such as elastance, can be used to categorise and model HF, complementing the existing classification. The modelled PV loops establish previously unknown physiological parameters for each AHA/ACC stage of LVSD-HF, such as LV elastance and highlight that it this parameter alone, in lumped parameter models, that determines the severity of HF. Such information will enable cardiovascular modellers with an interest in HF, to create more accurate models of the heart as it fails.

  20. Closing the loop: modelling of heart failure progression from health to end-stage using a meta-analysis of left ventricular pressure-volume loops.

    Directory of Open Access Journals (Sweden)

    David R Warriner

    Full Text Available INTRODUCTION: The American Heart Association (AHA/American College of Cardiology (ACC guidelines for the classification of heart failure (HF are descriptive but lack precise and objective measures which would assist in categorising such patients. Our aim was two fold, firstly to demonstrate quantitatively the progression of HF through each stage using a meta-analysis of existing left ventricular (LV pressure-volume (PV loop data and secondly use the LV PV loop data to create stage specific HF models. METHODS AND RESULTS: A literature search yielded 31 papers with PV data, representing over 200 patients in different stages of HF. The raw pressure and volume data were extracted from the papers using a digitising software package and the means were calculated. The data demonstrated that, as HF progressed, stroke volume (SV, ejection fraction (EF% decreased while LV volumes increased. A 2-element lumped parameter model was employed to model the mean loops and the error was calculated between the loops, demonstrating close fit between the loops. The only parameter that was consistently and statistically different across all the stages was the elastance (Emax. CONCLUSIONS: For the first time, the authors have created a visual and quantitative representation of the AHA/ACC stages of LVSD-HF, from normal to end-stage. The study demonstrates that robust, load-independent and reproducible parameters, such as elastance, can be used to categorise and model HF, complementing the existing classification. The modelled PV loops establish previously unknown physiological parameters for each AHA/ACC stage of LVSD-HF, such as LV elastance and highlight that it this parameter alone, in lumped parameter models, that determines the severity of HF. Such information will enable cardiovascular modellers with an interest in HF, to create more accurate models of the heart as it fails.

  1. Use of a Distributed, Finite-Volume, Hydrologic Model to Assess the Sensitivity of the Everglades to De-compartmentalization

    Science.gov (United States)

    Senarath, S. U.

    2002-12-01

    The Everglades, the only remaining subtropical wilderness in the continental USA, is the home to a number of threatened and endangered species. Although the pre-drainage Everglades covered an area of approximately 11,048 km2, urbanization and farming have reduced its area by approximately 50%. The remaining Everglades has also changed as a result of drainage and compartmentalization by over 2,200 km of levees and canals. This area is also adversely affected by exotic species, nutrient enrichment, contaminants and altered freshwater flows. The \\8 billion Comprehensive Everglades Restoration Plan provides a ``framework and guide to restore, protect, and preserve the water resources of central and southern Florida, including the Everglades.'' The success of this project, one of the largest eco-system restoration projects in the world, depends heavily on our understanding of the quantity, quality, timing and distribution of South Florida's pre-drainage freshwater flow. Consequently, accurate hydrologic modeling is crucial for the restoration of the greater Everglades ecosystem. The Regional Simulation Model (RSM) developed by the South Florida Water Management District is currently being used to investigate the effect of de-compartmentalization on freshwater flow dynamics in parts of the remaining Everglades which includes the Everglades National Park and the Big Cypress National Preserve. The RSM is an implicit, finite-volume, continuous, distributed, integrated surface/ground-water model, capable of simulating one-dimensional canal flow and two-dimensional overland flow in arbitrarily shaped areas using a variable triangular mesh. It has physically-based formulations for the simulation of overland and groundwater flow, evapo-transpiration, infiltration, levee seepage, and canal and structure flows. It is capable of simulating features that are unique to South Florida such as low-relief topography, high water tables, saturation-excess runoff, depth

  2. Spatial relationship of source localizations in patients with focal epilepsy: Comparison of MEG and EEG with a three spherical shells and a boundary element volume conductor model.

    Science.gov (United States)

    Scheler, Gabriela; Fischer, Michael J M; Genow, Alexandra; Hummel, Cornelia; Rampp, Stefan; Paulini, Andrea; Hopfengärtner, Rüdiger; Kaltenhäuser, Martin; Stefan, Hermann

    2007-04-01

    Epilepsy surgery is an option for patients with pharmacoresistant focal epilepsies, but it requires a precise focus localization procedure. Magnetoencephalography (MEG) and electroencephalography (EEG) can be used for analysis of interictal activity. The aim of this prospective study was to compare clusters of source localization results with MEG and EEG using a three spherical shells (3SS) and a boundary element method (BEM) volume conductor model. The study was closed when 100 patients met the inclusion criteria. Simultaneous MEG and EEG were recorded during presurgical evaluation. Epileptiform signals were analyzed using an equivalent current dipole model. Centroids of source localizations from MEG, EEG, 3SS, and BEM in their respective combinations were compared. In a 3SS model, MEG source localizations were 5.6 mm inferior to those obtained by EEG, while in a BEM model MEG source localizations were 6.3 mm anterior and 4.8 mm superior. The mean scattering of source localizations between both volume conductor models was 19.5 mm for EEG and 9.6 mm for MEG. For MEG no systematic difference between BEM and 3SS source localizations was found. For EEG, source localizations with BEM were 5.9 mm posterior and 11.7 mm inferior to those determined using 3SS. No differences were found between the 46 temporal and the 54 extratemporal lobe epilepsy patients. The observed systematic differences of source localizations of epileptic spikes due to the applied source signal modality and volume conductor model should be considered in presurgical evaluation when only one source signal and volume conductor model is available. (c) 2006 Wiley-Liss, Inc.

  3. Gluten-free diet increases beta-cell volume and improves glucose tolerance in an animal model of type 2 diabetes.

    Science.gov (United States)

    Haupt-Jorgensen, Martin; Buschard, Karsten; Hansen, Axel K; Josefsen, Knud; Antvorskov, Julie Christine

    2016-10-01

    Gluten-free (GF) diet alleviates type 1 diabetes in animal models and possibly in humans. We recently showed that fatty acid-induced insulin secretion is enhanced by enzymatically digested gluten (gliadin) stimulation in INS-1E insulinoma cells. We therefore hypothesized that GF diet would induce beta-cell rest and ameliorate type 2 diabetes. C57BL/6JBomTac (B6) mice were fed a high-fat (HF), gluten-free high-fat (GF-HF), standard (STD) or gluten-free (GF) diet for 42 weeks. Short-term (6-24 weeks) GF-HF versus HF feeding impaired glucose tolerance and increased fasting glucose. Long-term (36-42 weeks) GF-HF versus HF feeding improved glucose tolerance and decreased fasting leptin. Mice fed a GF-HF versus HF diet for 42 weeks showed higher volumes of beta cells, islets and pancreas. The beta-cell volume correlated with the islet- and pancreas volume as well as body weight. GF-HF versus HF diet did not influence toll-like receptor 4 (Tlr4), interleukin 1 (IL-1), interleukin 6 (IL-6) or tumour necrosis factor-alpha (TNF-alpha) mRNA expression in intestine. STD versus GF feeding did not affect any parameter studied. Long-term feeding with GF-HF versus HF increases beta-cell volume and improves glucose tolerance in B6 mice. The mechanism may include beta-cell rest, but is unlikely to include TLR4 and proinflammatory cytokines in the intestine. Beta-cell volume correlates with pancreas volume and body weight, indicating that insulin secretion capacity controls pancreas volume. Thus, long-term GF diets may be beneficial for obese type 2 diabetes patients and trials should be performed. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  4. International Energy Agency Building Energy Simulation Test and Diagnostic Method for Heating, Ventilating, and Air-Conditioning Equipment Models (HVAC BESTEST): Volume 2: Cases E300-E545.

    Energy Technology Data Exchange (ETDEWEB)

    Neymark J.; Judkoff, R.

    2004-12-01

    This report documents an additional set of mechanical system test cases that are planned for inclusion in ANSI/ASHRAE STANDARD 140. The cases test a program's modeling capabilities on the working-fluid side of the coil, but in an hourly dynamic context over an expanded range of performance conditions. These cases help to scale the significance of disagreements that are less obvious in the steady-state cases. The report is Vol. 2 of HVAC BESTEST Volume 1. Volume 1 was limited to steady-state test cases that could be solved with analytical solutions. Volume 2 includes hourly dynamic effects, and other cases that cannot be solved analytically. NREL conducted this work in collaboration with the Tool Evaluation and Improvement Experts Group under the International Energy Agency (IEA) Solar Heating and Cooling Programme Task 22.

  5. Computational Modeling to Limit the Impact Displays and Indicator Lights Have on Habitable Volume Operational Lighting Constraints

    Science.gov (United States)

    Clark, T. A.; Brainard, G.; Salazar, G.; Johnston, S.; Schwing, B.; Litaker, H.; Kolomenski, A.; Venus, D.; Tran, K.; Hanifin, J.; hide

    2017-01-01

    NASA has demonstrated an interest in improving astronaut health and performance through the installment of a new lighting countermeasure on the International Space Station. The Solid State Lighting Assembly (SSLA) system is designed to positively influence astronaut health by providing a daily change to light spectrum to improve circadian entrainment. Unfortunately, existing NASA standards and requirements define ambient light level requirements for crew sleep and other tasks, yet the number of light-emitting diode (LED) indicators and displays within a habitable volume is currently uncontrolled. Because each of these light sources has its own unique spectral properties, the additive lighting environment ends up becoming something different from what was planned or researched. Restricting the use of displays and indicators is not a solution because these systems provide beneficial feedback to the crew. The research team for this grant used computer-based computational modeling and real-world lighting mockups to document the impact that light sources other than the ambient lighting system contribute to the ambient spectral lighting environment. In particular, the team was focused on understanding the impacts of long-term tasks located in front of avionics or computer displays. The team also wanted to understand options for mitigating the changes to the ambient light spectrum in the interest of maintaining the performance of a lighting countermeasure. The project utilized a variety of physical and computer-based simulations to determine direct relationships between system implementation and light spectrum. Using real-world data, computer models were built in the commercially available optics analysis software Zemax Optics Studio(c). The team also built a mockup test facility that had the same volume and configuration as one of the Zemax models. The team collected over 1200 spectral irradiance measurements, each representing a different configuration of the mockup

  6. Cyclic PaO2 oscillations assessed in the renal microcirculation: correlation with tidal volume in a porcine model of lung lavage.

    Science.gov (United States)

    Thomas, Rainer; Möllmann, Christian; Ziebart, Alexander; Liu, Tanghua; David, Matthias; Hartmann, Erik K

    2017-07-11

    Oscillations of the arterial partial pressure of oxygen induced by varying shunt fractions occur during cyclic alveolar recruitment within the injured lung. Recently, these were proposed as a pathomechanism that may be relevant for remote organ injury following acute respiratory distress syndrome. This study examines the transmission of oxygen oscillations to the renal tissue and their tidal volume dependency. Lung injury was induced by repetitive bronchoalveolar lavage in eight anaesthetized pigs. Cyclic alveolar recruitment was provoked by high tidal volume ventilation. Oscillations of the arterial partial pressure of oxygen were measured in real-time in the macrocirculation by multi-frequency phase fluorimetry and in the renal microcirculation by combined white-light spectrometry and laser-Doppler flowmetry during tidal volume down-titration. Significant respiratory-dependent oxygen oscillations were detected in the macrocirculation and transmitted to the renal microcirculation in a substantial extent. The amplitudes of these oscillations significantly correlate to the applied tidal volume and are minimized during down-titration. In a porcine model oscillations of the arterial partial pressure of oxygen are induced by cyclic alveolar recruitment and transmitted to the renal microcirculation in a tidal volume-dependent fashion. They might play a role in organ crosstalk and remote organ damage following lung injury.

  7. Soy protein diet and exercise training increase relative bone volume and enhance bone microarchitecture in a mouse model of uremia.

    Science.gov (United States)

    Tomayko, Emily J; Chung, Hae R; Wilund, Kenneth R

    2011-11-01

    Soy protein consumption and exercise training have been widely studied for their effects on the vasculature and bone in healthy populations, but little is known about the effectiveness of these interventions in chronic kidney disease (CKD). Cardiovascular disease and bone fracture risk are significantly elevated in CKD, and current pharmacological interventions have been unsuccessful in treating these conditions simultaneously. The purpose of this study was to compare the effects of a soy protein diet and endurance exercise training, alone or in combination, on cardiovascular and bone health in a mouse model of renal insufficiency. At 8 weeks of age, 60 female apolipoprotein E(-/-) mice underwent a two-step surgical procedure to induce uremia. These mice were then randomized at 12 weeks of age to one of four treatment groups for the 16-week intervention period: sedentary, control diet (n = 16); sedentary, soy protein diet (n = 18); exercise, control diet (n = 14); and exercise, soy protein diet (n = 12). There were no significant treatment effects on atherosclerotic lesion areas or aortic calcium deposits. We demonstrated a significant main effect of both diet and exercise on relative bone volume, trabecular number, trabecular separation, and trabecular connective density in the proximal femur as measured by microcomputed tomography. There were no treatment effects on trabecular thickness. We also showed a main effect of diet on plasma urea levels. These data suggest that soy protein intake and exercise training exert beneficial effects on properties of bone and plasma urea levels in mice with surgically induced renal impairment. © The Japanese Society for Bone and Mineral Research and Springer 2011

  8. Experimental subarachnoid hemorrhage: subarachnoid blood volume, mortality rate, neuronal death, cerebral blood flow, and perfusion pressure in three different rat models.

    Science.gov (United States)

    Prunell, Giselle Fabiana; Mathiesen, Tiit; Diemer, Nils Henrik; Svendgaard, Niels-Aage

    2003-01-01

    To investigate which of three subarachnoid hemorrhage (SAH) models is the most suitable for studies of pathological and pathophysiological processes after SAH. SAH was induced in rats via intracranial endovascular perforation (perforation model), blood injection into the cisterna magna (300 microl), or blood injection into the prechiasmatic cistern (200 microl). The subarachnoid blood volume was quantitatively measured. Cerebral blood flow (CBF) (as assessed with laser Doppler flowmetry), intracranial pressure, and mean arterial blood pressure were recorded for 90 minutes after SAH. Mortality was recorded, and neuronal death was assessed in animals that survived 7 days after SAH. The subarachnoid blood volume was close to the injected amount after prechiasmatic SAH. In the other models, the volume varied between 40 and 480 microl. The mortality rates were 44% in the perforation SAH group, 25% in the prechiasmatic SAH group, and 0% in the cisterna magna SAH group; the corresponding values for neuronal death were 11, 44, and 28%. Cerebral perfusion pressure approached baseline values within 5 minutes after SAH in all three models. CBF decreased to approximately 35% of baseline values immediately after SAH in all groups; it gradually increased to normal values 15 minutes after SAH in the cisterna magna SAH group and to 60 and 89% of baseline values 90 minutes post-SAH in the perforation and prechiasmatic SAH groups. CBF was significantly correlated with the subarachnoid blood volume. The prechiasmatic SAH model seems to be the most suitable for study of the sequelae after SAH; it produces a significant decrease in CBF, an acceptable mortality rate, and substantial pathological lesions, with high reproducibility. The CBF reduction is predominantly dependent on the amount of subarachnoid blood.

  9. Application of Compressible Volume of Fluid Model in Simulating the Impact and Solidification of Hollow Spherical ZrO2 Droplet on a Surface

    Science.gov (United States)

    Safaei, Hadi; Emami, Mohsen Davazdah; Jazi, Hamidreza Salimi; Mostaghimi, Javad

    2017-12-01

    Applications of hollow spherical particles in thermal spraying process have been developed in recent years, accompanied by attempts in the form of experimental and numerical studies to better understand the process of impact of a hollow droplet on a surface. During such process, volume and density of the trapped gas inside droplet change. The numerical models should be able to simulate such changes and their consequent effects. The aim of this study is to numerically simulate the impact of a hollow ZrO2 droplet on a flat surface using the volume of fluid technique for compressible flows. An open-source, finite-volume-based CFD code was used to perform the simulations, where appropriate subprograms were added to handle the studied cases. Simulation results were compared with the available experimental data. Results showed that at high impact velocities ( U 0 > 100 m/s), the compression of trapped gas inside droplet played a significant role in the impact dynamics. In such velocities, the droplet splashed explosively. Compressibility effects result in a more porous splat, compared to the corresponding incompressible model. Moreover, the compressible model predicted a higher spread factor than the incompressible model, due to planetary structure of the splat.

  10. On Assumptions in Development of a Mathematical Model of Thermo-gravitational Convection in the Large Volume Process Tanks Taking into Account Fermentation

    Directory of Open Access Journals (Sweden)

    P. M. Shkapov

    2015-01-01

    Full Text Available The paper provides a mathematical model of thermo-gravity convection in a large volume vertical cylinder. The heat is removed from the product via the cooling jacket at the top of the cylinder. We suppose that a laminar fluid motion takes place. The model is based on the NavierStokes equation, the equation of heat transfer through the wall, and the heat transfer equation. The peculiarity of the process in large volume tanks was the distribution of the physical parameters of the coordinates that was taken into account when constructing the model. The model corresponds to a process of wort beer fermentation in the cylindrical-conical tanks (CCT. The CCT volume is divided into three zones and for each zone model equations was obtained. The first zone has an annular cross-section and it is limited to the height by the cooling jacket. In this zone the heat flow from the cooling jacket to the product is uppermost. Model equation of the first zone describes the process of heat transfer through the wall and is presented by linear inhomogeneous differential equation in partial derivatives that is solved analytically. For the second and third zones description there was a number of engineering assumptions. The fluid was considered Newtonian, viscous and incompressible. Convective motion considered in the Boussinesq approximation. The effect of viscous dissipation is not considered. The topology of fluid motion is similar to the cylindrical Poiseuille. The second zone model consists of the Navier-Stokes equations in cylindrical coordinates with the introduction of a simplified and the heat equation in the liquid layer. The volume that is occupied by an upward convective flow pertains to the third area. Convective flows do not mix and do not exchange heat. At the start of the process a medium has the same temperature and a zero initial velocity in the whole volume that allows us to specify the initial conditions for the process. The paper shows the

  11. Time-dependent model for volume changes in pressure sources at Asama volcano, central Japan due to vertical deformations detected by precise leveling during 1902 2005

    Science.gov (United States)

    Murase, Masayuki; Ono, Koji; Ito, Takeo; Miyajima, Rikio; Mori, Hitoshi; Aoyama, Hiroshi; Oshima, Hiromitu; Yoshida, Yuka; Terada, Akihiko; Koyama, Eturo; Takeda, Toyotarou; Watanabe, Hidefumi; Kimata, Fumiaki; Fujii, Naoyuki

    2007-07-01

    A time-dependent model for volume changes in pressure sources at Asama volcano is developed from precise leveling data collected since 1902. The optimal source model is determined by comparing five different models (a model with three types of spherical sources, single dike, and dike with a spherical source) during three periods: 1935 to 1939, 1939 to 1950/1953, and 1990 to November 2004. The optimal parameters for each model are estimated by employing a genetic algorithm (GA). The model with two spherical sources was selected as the optimal model. In this model, one of the sources was estimated to be located at a depth of approximately 6 km beneath Kurofu volcano; the other source was estimated to be located close to Maekake volcano at a depth of approximately 2 km. The volume changes in the two spherical sources are calculated using the Akaike's Bayesian information criterion (ABIC) for the period from 1902 to 2005. During the period from 1902 to 1943, a large inflation was estimated in a source at a depth of approximately 6 km beneath Kurofu volcano, which is an older volcano at the base of Asama. After 1943, a rapid deflation continued until 1967. This rapid deflation changed to a marginal inflation that continued from 1967 until 2005. The temporal change in the pressure source beneath Kurofu volcano exhibits a strong positive correlation with the eruption frequency. The leveling data does not suggest a significant volume change in the source beneath Kurofu volcano during the quiet period between 1962 and 2005. During the 20th century, magma appears to have been episodically supplied beneath Asama volcano. In particular, the inflation of the source beneath Kurofu volcano, and probably the magma supply, reached a peak from 1930 to 1940.

  12. JANNAF 25th Airbreathing Propulsion Subcommittee, 37th Combustion Subcommittee and 1st Modeling and Simulation Subcommittee Joint Meeting. Volume 1

    Science.gov (United States)

    Fry, Ronald S.; Becker, Dorothy L.

    2000-01-01

    Volume I, the first of three volumes, is a compilation of 24 unclassified/unlimited-distribution technical papers presented at the Joint Army-Navy-NASA-Air Force (JANNAF) 25th Airbreathing Propulsion Subcommittee, 37th Combustion Subcommittee and 1st Modeling and Simulation Subcommittee (MSS) meeting held jointly with the 19th Propulsion Systems Hazards Subcommittee. The meeting was held 13-17 November 2000 at the Naval Postgraduate School and Hyatt Regency Hotel, Monterey, California. Topics covered include: a Keynote Address on Future Combat Systems, a review of the new JANNAF Modeling and Simulation Subcommittee, and technical papers on Hyper-X propulsion development and verification; GTX airbreathing launch vehicles; Hypersonic technology development, including program overviews, fuels for advanced propulsion, ramjet and scramjet research, hypersonic test medium effects; and RBCC engine design and performance, and PDE and UCAV advanced and combined cycle engine technologies.

  13. A Study of the Transient Response of Duct Junctions: Measurements and Gas-Dynamic Modeling with a Staggered Mesh Finite Volume Approach

    Directory of Open Access Journals (Sweden)

    Antonio J. Torregrosa

    2017-05-01

    Full Text Available Duct junctions play a major role in the operation and design of most piping systems. The objective of this paper is to establish the potential of a staggered mesh finite volume model as a way to improve the description of the effect of simple duct junctions on an otherwise one-dimensional flow system, such as the intake or exhaust of an internal combustion engine. Specific experiments have been performed in which different junctions have been characterized as a multi-port, and that have provided precise and reliable results on the propagation of pressure pulses across junctions. The results obtained have been compared to simulations performed with a staggered mesh finite volume method with different flux limiters and different meshes and, as a reference, have also been compared with the results of a more conventional pressure loss-based model. The results indicate that the staggered mesh finite volume model provides a closer description of wave dynamics, even if further work is needed to establish the optimal calculation settings.

  14. Prediction of the Individual Wave Overtopping Volumes of a Wave Energy Converter using Experimental Testing and First Numerical Model Results

    DEFF Research Database (Denmark)

    Victor, L.; Troch, P.; Kofoed, Jens Peter

    2009-01-01

    For overtopping wave energy converters (WECs) a more efficient energy conversion can be achieved when the volumes of water, wave by wave, that enter their reservoir are known and can be predicted. A numerical tool is being developed using a commercial CFD-solver to study and optimize...

  15. The Importance of psychological constructs for training volume and performance improvement. A structural equation model for youth speed skaters

    NARCIS (Netherlands)

    Elferink-Gemser, Marije T.; De Roos, Ilse; Torenbeek, Marjolein; Fokkema, Tryntsje; Jonker, Laura; Visscher, Chris

    2015-01-01

    To investigate the importance of self-regulated learning, motivation, and goal orientation for training volume and performance improvement, 63 talented Dutch speed skaters (n=35 male; n=28 female) aged 11 to 22 completed the Self-Regulation of Learning-Self-Report Scale (SRL-SRS; Toering et al.,

  16. An initial abstraction and constant loss model, and methods for estimating unit hydrographs, peak streamflows, and flood volumes for urban basins in Missouri

    Science.gov (United States)

    Huizinga, Richard J.

    2014-01-01

    Streamflow data, basin characteristics, and rainfall data from 39 streamflow-gaging stations for urban areas in and adjacent to Missouri were used by the U.S. Geological Survey in cooperation with the Metropolitan Sewer District of St. Louis to develop an initial abstraction and constant loss model (a time-distributed basin-loss model) and a gamma unit hydrograph (GUH) for urban areas in Missouri. Study-specific methods to determine peak streamflow and flood volume for a given rainfall event also were developed.

  17. In a Canine Pneumonia Model of Exchange-Transfusion, Altering the Age but Not the Volume of Older Red Blood Cells Markedly Alters Outcome

    Science.gov (United States)

    Cortés-Puch, Irene; Remy, Kenneth E.; Solomon, Steven B.; Sun, Junfeng; Wang, Dong; Al-Hamad, Mariam; Kelly, Seth M.; Sinchar, Derek; Bellavia, Landon; Kanias, Tamir; Popovsky, Mark A.; Kim-Shapiro, Daniel B.; Klein, Harvey G.; Natanson, Charles

    2015-01-01

    Background Massive exchange-transfusion of 42-day-old red blood cells (RBCs) in a canine model of S. aureus pneumonia resulted in in vivo hemolysis with increases in cell-free hemoglobin (CFH), transferrin bound iron (TBI), non-transferrin bound iron (NTBI), and mortality. We have previously shown that washing 42-day-old RBCs before transfusion significantly decreased NTBI levels and mortality, but washing 7-day-old RBCs increased mortality and CFH levels. We now report the results of altering volume, washing, and age of RBCs. Study Design and Methods Two-year-old purpose-bred infected beagles were transfused with increasing volumes (5-10, 20-40, or 60-80 mL/kg) of either 42- or 7-day-old RBCs (n=36) or 80 mL/kg of either unwashed or washed RBCs with increasing storage age (14, 21, 28, or 35 days) (n=40). Results All volumes transfused (5-80 mL/kg) of 42-day-old RBCs, resulted in alike (i.e., not significantly different) increases in TBI during transfusion as well as in CFH, lung injury, and mortality rates after transfusion. Transfusion of 80 mL/kg of RBCs stored for 14, 21, 28 and 35 days resulted in increased CFH and NTBI in between levels found at 7 and 42 days of storage. However, washing RBCs of intermediate ages (14-35 days) does not alter NTBI and CFH levels or mortality rates. Conclusions Preclinical data suggest that any volume of 42-day-old blood potentially increases risks during established infection. In contrast, even massive volumes of 7-day-old blood result in minimal CFH and NTBI levels and risks. In contrast to the extremes of storage, washing blood stored for intermediate ages does not alter risks of transfusion or NTBI and CFH clearance. PMID:26469998

  18. Estimates of volume and magma input in crustal magmatic systems from zircon geochronology: the effect of modelling assumptions and system variables

    Directory of Open Access Journals (Sweden)

    Luca eCaricchi

    2016-04-01

    Full Text Available Magma fluxes in the Earth’s crust play an important role in regulating the relationship between the frequency and magnitude of volcanic eruptions, the chemical evolution of magmatic systems and the distribution of geothermal energy and mineral resources on our planet. Therefore, quantifying magma productivity and the rate of magma transfer within the crust can provide valuable insights to characterise the long-term behaviour of volcanic systems and to unveil the link between the physical and chemical evolution of magmatic systems and their potential to generate resources. We performed thermal modelling to compute the temperature evolution of crustal magmatic intrusions with different final volumes assembled over a variety of timescales (i.e., at different magma fluxes. Using these results, we calculated synthetic populations of zircon ages assuming the number of zircons crystallising in a given time period is directly proportional to the volume of magma at temperature within the zircon crystallisation range. The statistical analysis of the calculated populations of zircon ages shows that the mode, median and standard deviation of the populations varies coherently as function of the rate of magma injection and final volume of the crustal intrusions. Therefore, the statistical properties of the population of zircon ages can add useful constraints to quantify the rate of magma injection and the final volume of magmatic intrusions.Here, we explore the effect of different ranges of zircon saturation temperature, intrusion geometry, and wall rock temperature on the calculated distributions of zircon ages. Additionally, we determine the effect of undersampling on the variability of mode, median and standards deviation of calculated populations of zircon ages to estimate the minimum number of zircon analyses necessary to obtain meaningful estimates of magma flux and final intrusion volume.

  19. Paleoclimatology: a survey on ancient climates. Volume 1 - To find, date and interpret indices; Volume 2 - To fit the puzzle pieces one to the other: to understand and model a complex system

    International Nuclear Information System (INIS)

    Duplessy, J.C.; Ramstein, G.; Berger, A.; Joussaume, S.; Guillou, H.; Paterne, M.; Michel, E.; Hatte, C.; Dutay, J.C.; Nomade, S.; Scaillet, S.; Frank, N.; Salle, E.; Laj, C.; Channell, J.E.T.; Kissel, C.; Guibal, F.; Guiot, J.; Parrenin, F.; Masson-Delmotte, V.; Jouzel, J.; Rousseau, D.D.; Genty, D.; Von Grafenstein, U.; Belmecheri, S.; Daux, V.; Williamson, D.; Gasse, F.; Vimeux, F.; Cortijo, E.; Labeyrie, L.; Bopp, L.; Friedlingstein, P.; Chappellaz, J.; Legrand, M.; Delmas, R.; Ritz, C.; Peyaud, V.; Waelbroeck, C.; Colleoni, F.; Fluteau, F.; Kageyama, M.; Paillard, D.; Godderis, Y.; Le Hir, G.; Donnadieu, Y.; Roche, D.M.; Combourieu Nebout, N.; Braconnot, P.; Yiou, P.; Charbit, S.; Dufresne, J.L.; Cattiaux, J.

    2013-11-01

    The first volume of this collective publication gathers contributions on techniques used to reconstruct past climates. The chapters address the climate system operation and history (evolution, mechanisms, the atmosphere, oceans, ground and marine biosphere, cryo-sphere, lithosphere), propose an introduction to geochronology, present and discuss various dating methods (carbon 14, K-Ar and Ar-Ar methods, dating of corals and other geological samples based the disequilibrium between uranium and thorium isotopes, use of magnetic stratigraphy, dendro-chronology, dating of ice archives), discuss how to reconstruct atmosphere physics and circulation, address the use and properties of different interfaces (air-ice with polar ices, air-plants with pollen, air-soil with loessic sequences as markers of atmospheric circulation or reconstruction of paleo-climates with speleothems, air-lake, plant-atmosphere, air-plant, air-water, air-ice in tropical glaciers), and discuss the use of paleo-oceanography data. The second volume gathers contributions in which the authors present the most recent approaches used to reconstruct the operation of the climate system in the past by using present observations and models. The chapters address the biochemistry of the climate system during the last million of years, the relationship between cryo-sphere and sea level, the climate at the scale of geological times, modelling approaches in paleoclimatology, the Precambrian climate, the Phanerozoic climates, the relationship between climate and astronomic cycles, the description and mechanisms of quick climate variability, the Holocene and the anthropogenic perturbation, and the evolution from past climates to future climates

  20. Use of fractional dose–volume histograms to model risk of acute rectal toxicity among patients treated on RTOG 94-06

    International Nuclear Information System (INIS)

    Tucker, Susan L.; Michalski, Jeff M.; Bosch, Walter R.; Mohan, Radhe; Dong, Lei; Winter, Kathryn; Purdy, James A.; Cox, James D.

    2012-01-01

    Background and purpose: For toxicities occurring during the course of radiotherapy, it is conceptually inaccurate to perform normal-tissue complication probability analyses using the complete dose–volume histogram. The goal of this study was to analyze acute rectal toxicity using a novel approach in which the fit of the Lyman–Kutcher–Burman (LKB) model is based on the fractional rectal dose–volume histogram (DVH). Materials and methods: Grade ⩾2 acute rectal toxicity was analyzed in 509 patients treated on Radiation Therapy Oncology Group (RTOG) protocol 94-06. These patients had no field reductions or treatment-plan revisions during therapy, allowing the fractional rectal DVH to be estimated from the complete rectal DVH based on the total number of dose fractions delivered. Results: The majority of patients experiencing Grade ⩾2 acute rectal toxicity did so before completion of radiotherapy (70/80 = 88%). Acute rectal toxicity depends on fractional mean rectal dose, with no significant improvement in the LKB model fit when the volume parameter differs from n = 1. The incidence of toxicity was significantly lower for patients who received hormone therapy (P = 0.024). Conclusions: Variations in fractional mean dose explain the differences in incidence of acute rectal toxicity, with no detectable effect seen here for differences in numbers of dose fractions delivered.

  1. Lithofacies modeling by multipoint statistics and economic evaluation by NPV volume for the early Cretaceous Wabiskaw Member in Athabasca oilsands area, Canada

    Directory of Open Access Journals (Sweden)

    Kwang Hyun Kim

    2018-03-01

    As Wabiskaw Member is frontier oilsands lease, it is impossible to evaluate the economics from production data or dynamic simulation. In this study, a dynamic steam assisted gravity drainage (SAGD performance indicator (SPIDER on the basis of reservoir characteristics is calculated to build 3D reservoir model for the evaluation of the SAGD feasibility in Wabiskaw Member. SPIDER depends on reservoir properties, economic limit of steam-oil ratio, and bitumen price. Reservoir properties like porosity, permeability, and water saturation are measured from 13 cores and calculated from 201 well-logs. Three dimensional volumes of reservoir properties are constructed mostly based on relationships among properties. Finally, net present value (NPV volume can be built by equation relating NPV and SPIDER. The economic area exceeding criterion of US$ 10,000 is identified, and the ranges of reservoir properties are estimated. NPV-volume-generation workflow from reservoir parameter to static model provides cost- and time- effective method to evaluate the oilsands SAGD project.

  2. Carbogen Breathing Differentially Enhances Blood Plasma Volume and 5-Fluorouracil Uptake in Two Murine Colon Tumor Models with a Distinct Vascular Structure

    Directory of Open Access Journals (Sweden)

    Hanneke W.M. van Laarhoven

    2006-06-01

    Full Text Available For the systemic treatment of colorectal cancer, 5-fluorouracil (FU-based chemotherapy is the standard. However, only a subset of patients responds to chemotherapy. Breathing of carbogen (95% O2 and 5% CO2 may increase the uptake of FU through changes in tumor physiology. This study aims to monitor in animal models in vivo the effects of carbogen breathing on tumor blood plasma volume, pH, and energy status, and on FU uptake and metabolism in two colon tumor models C38 and C26a, which differ in their vascular structure and hypoxic status. Phosphorus-31 magnetic resonance spectroscopy (MRS was used to assess tumor pH and energy status, and fluorine-19 MRS was used to follow FU uptake and metabolism. Advanced magnetic resonance imaging methods using ultrasmall particles of iron oxide were performed to assess blood plasma volume. The results showed that carbogen breathing significantly decreased extracellular pH and increased tumor blood plasma volume and FU uptake in tumors. These effects were most significant in the C38 tumor line, which has the largest relative vascular area. In the C26a tumor line, carbogen breathing increased tumor growth delay by FU. In this study, carbogen breathing also enhanced systemic toxicity by FU.

  3. Feasibility Study for an Air Force Environmental Model and Data Exchange. Volume 4. Appendix G. Model Review and Index-Air Multimedia and Other Models, Plus Data Bases.

    Science.gov (United States)

    1983-07-01

    radiological decay. The food path- way model (vegetable, meat and milk ) is consistent with that in Reg. Guide 1.109 (NRC77). Ingrowth for...20460 Phone: (202) 426-7778 Pollutants tests included in database dissolved oxygen fecal coliform nitrogen 7727-37-9 oxygen demand ph phosphorus 7723-14...included in database: acidity alkalinity dissolved oxygen dissolved solids 5_’ fecal coliform nitrogen 7727-37-9 259 - Oil and grease oxygen demand ph

  4. Renewable Resources: a national catalog of model projects. Volume 2. Mid-American Solar Energy Complex Region

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-07-01

    This compilation of diverse conservation and renewable energy projects across the United States was prepared through the enthusiastic participation of solar and alternate energy groups from every state and region. Compiled and edited by the Center for Renewable Resources, these projects reflect many levels of innovation and technical expertise. In many cases, a critique analysis is presented of how projects performed and of the institutional conditions associated with their success or failure. Some 2000 projects are included in this compilation; most have worked, some have not. Information about all is presented to aid learning from these experiences. The four volumes in this set are arranged in state sections by geographic region, coinciding with the four Regional Solar Energy Centers. The table of contents is organized by project category so that maximum cross-referencing may be obtained. This volume includes information on the Mid-American Solar Energy Complex Region. (WHK)

  5. Towards a universal method for calculating hydration free energies: a 3D reference interaction site model with partial molar volume correction.

    Science.gov (United States)

    Palmer, David S; Frolov, Andrey I; Ratkova, Ekaterina L; Fedorov, Maxim V

    2010-12-15

    We report a simple universal method to systematically improve the accuracy of hydration free energies calculated using an integral equation theory of molecular liquids, the 3D reference interaction site model. A strong linear correlation is observed between the difference of the experimental and (uncorrected) calculated hydration free energies and the calculated partial molar volume for a data set of 185 neutral organic molecules from different chemical classes. By using the partial molar volume as a linear empirical correction to the calculated hydration free energy, we obtain predictions of hydration free energies in excellent agreement with experiment (R = 0.94, σ = 0.99 kcal mol (- 1) for a test set of 120 organic molecules).

  6. Applying a volume dipole distribution model to next-generation sensor data for multi-object data inversion and discrimination

    Science.gov (United States)

    Shubitidze, Fridon; Karkashadze, David; Fernández, Juan Pablo; Barrowes, Benjamin E.; O'Neill, Kevin; Grzegorczyk, Tomasz M.; Shamatava, Irma

    2010-04-01

    Discrimination between UXO and harmless objects is particularly difficult in highly contaminated sites where two or more objects are simultaneously present in the field of view of the sensor and produce overlapping signals. The first step in overcoming this problem is estimating the number of targets. In this work an orthonormalized volume magnetic source (ONVMS) approach is introduced for estimating the number of targets, along with their locations and orientations. The technique is based on the discrete dipole approximation, which distributes dipoles inside the computational volume. First, a set of orthogonal functions are constructed using fundamental solutions of the Helmholtz equations (i.e., Green's functions). Then, the scattered magnetic field is approximated as a series of these orthogonal functions. The magnitudes of the expansion coefficients are determined directly from the measurement data without solving an ill-posed inverse-scattering problem. The expansion coefficients are then used to determine the amplitudes of the responding volume magnetic dipoles. The algorithm's superior performance and applicability to live UXO sites are illustrated by applying it to the bi-static TEMTADS multi-target data sets collected by NRL personnel at the Aberdeen Proving Ground UXO teststand site.

  7. Modelagem do volume do povoamento para Mimosa scabrella Benth. na regição metropolitana de Curitiba Stand volume modelling of Mimosa scabrella benth. from Curitiba metropolitan region

    Directory of Open Access Journals (Sweden)

    Sebastião do Amaral Machado

    2008-06-01

    Full Text Available O objetivo desta pesquisa foi modelar o volume total com casca do povoamento da bracatinga (Mimosa scabrella Benth.. Coletaram-se dados em bracatingais com regeneração induzida pelo fogo, em 14 municípios da Região Metropolitana de Curitiba (RMC, Estado do Paraná - Brasil. Utilizou-se uma base de dados constituída por 229 unidades amostrais de 100 a 400 m². Em cada parcela, mensurou-se o diâmetro à altura do peito, bem como a altura total de todas as árvores, em bracatingais de 3 a 18 anos de idade. Para a estimativa do volume total com casca, testaram-se vários modelos de regressão selecionados da literatura, o que gerou uma matriz com 58 variáveis independentes, visando construir modelos por meio do método Stepwise. As equações de melhor ajuste foram validadas utilizando-se o teste Qui-quadrado, a análise gráfica de resíduos e o erro-padrão da estimativa. Várias equações tiveram bom desempenho, apresentaram valores de coeficiente de determinação ajustados superiores a 0,995, erro-padrão da estimativa inferior a 3% e adequada distribuição de resíduos. As duas equações de melhor desempenho foram validadas, apresentando erro-padrão da estimativa de 2,37% e 2,13%, valor não-significativo para o teste do Qui-quadrado e equilibrada distribuição dos resíduos.The objective of this research was to model the stand volume outside bark of Mimosa scabrella Benth. stands, from the Curitiba Metropolitan Region (CMR, Parana State - Brazil. To reach this aim, a database of 229 permanent and temporary sample plots measuring from 100 to 400 m² each, from 14 municipalities in the CMR, was used. In each sample plot, the diameter at breast height and the total height of all 3- to 18-year-old bracatinga trees were measured. To estimate the total volume, regression models selected from the literature were tested. A set of 58 independent variables was generated also to construct models by the Stepwise method. The equations of best

  8. Deep-water Reservoir Modelling Using a volume-based approach on Full-Offset Seismic Data: Etim Field, Offshore Nigeria

    International Nuclear Information System (INIS)

    Nwaeri, E.; Zimbrick, G.; Proett, B.

    2002-01-01

    Reservoir characterization of deep-water deposits is a challenging task. Major issues to address include: (1) prediction of sand distribution away from well control, (2) definition of reservoir geometry and size, and (3) spatial placement of sand bodies in the geologic model. In a typical deep-water setting, lithostratigraphic correlation using well logs has been found to be unreliable. Seismic correlation is critical, but complications from mixed-impedance reservoir, and variations in frequency/phase content of available full stack data can arise.We describe a reservoir description workflow that utilizes both volume-and map-based conditioning tools, in the absence of AVO products. A good density of interpreted horizons was used to provide stratigraphic control on the volume interpretation techniques. Map pattern analysis of horizon slices helped focus environment of deposition (EOD) interpretations on key areas of reservoir development.A seismic wedge model helped develop an interpretation strategy and assess seismic data quality. Results showed that seed detection of trough-peak pairs gave a reasonable prediction of reservoir distribution at Etim.Seismic attributes were used to calibrate and predict net sand thickness. The predictions were integrated with EOD maps and well control to provide final net sand maps. Extracted geobodies from the sculpted seismic data were used to place sands in their proper position in the geologic model.The resulting geologic model preserves spatial positioning of the seismically derived reservoir elements and provides better definition of reservoir connectivity. This workflow is appropriate for fields where multi-volume (AVO) seismic data are unavailable and 3-D positioning of reservoir elements is required

  9. Activation of a chondrocyte volume-sensitive Cl(-) conductance prior to macroscopic cartilage lesion formation in the rabbit knee anterior cruciate ligament transection osteoarthritis model.

    Science.gov (United States)

    Kumagai, K; Toyoda, F; Staunton, C A; Maeda, T; Okumura, N; Matsuura, H; Matsusue, Y; Imai, S; Barrett-Jolley, R

    2016-10-01

    The anterior cruciate ligament transection (ACLT) rabbit osteoarthritis (OA) model confers permanent knee instability and induces joint degeneration. The degeneration process is complex, but includes chondrocyte apoptosis and OA-like loss of cartilage integrity. Previously, we reported that activation of a volume-sensitive Cl(-) current (ICl,vol) can mediate cell shrinkage and apoptosis in rabbit articular chondrocytes. Our objective was therefore to investigate whether ICl,vol was activated in the early stages of the rabbit ACLT OA model. Adult Rabbits underwent unilateral ACLT and contralateral arthrotomy (sham) surgery. Rabbits were euthanized at 2 or 4 weeks. Samples were analyzed histologically and with assays of cell volume, apoptosis and electrophysiological characterization of ICl,vol. At 2 and 4 weeks post ACLT cartilage appeared histologically normal, nevertheless cell swelling and caspase 3/7 activity were both significantly increased compared to sham controls. In cell-volume experiments, exposure of chondrocytes to hypotonic solution led to a greater increase in cell size in ACLT compared to controls. Caspase-3/7 activity, an indicator of apoptosis, was elevated in both ACLT 2wk and 4wk. Whole-cell currents were recorded with patch clamp of chondrocytes in iso-osmotic and hypo-osmotic external solutions under conditions where Na(+), K(+) and Ca(2+) currents were minimized. ACLT treatment resulted in a large increase in hypotonic-activated chloride conductance. Changes in chondrocyte ion channels take place prior to the onset of apparent cartilage loss in the ACLT rabbit model of OA. Further studies are needed to investigate if pharmacological inhibition of ICl,vol decreases progression of OA in animal models. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

  10. Correlation of In Vivo and In Vitro Methods in Measuring Choroidal Vascularization Volumes Using a Subretinal Injection Induced Choroidal Neovascularization Model

    Directory of Open Access Journals (Sweden)

    Chuang Nie

    2015-01-01

    Full Text Available Background: In vivo quantification of choroidal neovascularization (CNV based on noninvasive optical coherence tomography (OCT examination and in vitro choroidal flatmount immunohistochemistry stained of CNV currently were used to evaluate the process and severity of age-related macular degeneration (AMD both in human and animal studies. This study aimed to investigate the correlation between these two methods in murine CNV models induced by subretinal injection. Methods: CNV was developed in 20 C57BL6/j mice by subretinal injection of adeno-associated viral delivery of a short hairpin RNA targeting sFLT-1 (AAV.shRNA.sFLT-1, as reported previously. After 4 weeks, CNV was imaged by OCT and fluorescence angiography. The scaling factors for each dimension, x, y, and z (μm/pixel were recorded, and the corneal curvature standard was adjusted from human (7.7 to mice (1.4. The volume of each OCT image stack was calculated and then normalized by multiplying the number of voxels by the scaling factors for each dimension in Seg3D software (University of Utah Scientific Computing and Imaging Institute, available at http://www.sci.utah.edu/cibc-software/seg3d.html. Eighteen mice were prepared for choroidal flatmounts and stained by CD31. The CNV volumes were calculated using scanning laser confocal microscopy after immunohistochemistry staining. Two mice were stained by Hematoxylin and Eosin for observing the CNV morphology. Results: The CNV volume calculated using OCT was, on average, 2.6 times larger than the volume calculated using the laser confocal microscopy. The correlation statistical analysis showed OCT measuring of CNV correlated significantly with the in vitro method (R 2 =0.448, P = 0.001, n = 18. The correlation coefficient for CNV quantification using OCT and confocal microscopy was 0.693 (n = 18, P = 0.001. Conclusions: There is a fair linear correlation on CNV volumes between in vivo and in vitro methods in CNV models induced by subretinal

  11. Model studies on segmental movement in lumbar spine using a semi-automated program for volume fusion.

    Science.gov (United States)

    Svedmark, P; Weidenhielm, L; Nemeth, G; Tullberg, T; Noz, M E; Maguire, G Q; Zeleznik, M P; Olivecrona, H

    2008-01-01

    To validate a new non-invasive CT method for measuring segmental translations in lumbar spine in a phantom using plastic vertebrae with tantalum markers and human vertebrae. One hundred and four CT volumes were acquired of a phantom incorporating three lumbar vertebrae. Lumbar segmental translation was simulated by altering the position of one vertebra in all three cardinal axes between acquisitions. The CT volumes were combined into 64 case pairs, simulating lumbar segmental movement of up to 3 mm between acquisitions. The relative movement between the vertebrae was evaluated visually and numerically using a volume fusion image post-processing tool. Results were correlated to direct measurements of the phantom. On visual inspection, translation of at least 1 mm or more could be safely detected and correlated with separation between the vertebrae in three dimensions. There were no significant differences between plastic and human vertebrae. Numerically, the accuracy limit for all the CT measurements of the 3D segmental translations was 0.56 mm (median: 0.12; range: -0.76 to +0.49 mm). The accuracy for the sagittal axis was 0.45 mm (median: 0.10; range: -0.46 to +0.62 mm); the accuracy for the coronal axis was 0.46 mm (median: 0.09; range: -0.66 to +0.69 mm); and the accuracy for the axial axis was 0.45 mm (median: 0.05; range: -0.72 to + 0.62 mm). The repeatability, calculated over 10 cases, was 0.35 mm (median: 0.16; range: -0.26 to +0.30 mm). The accuracy of this non-invasive method is better than that of current routine methods for detecting segmental movements. The method allows both visual and numerical evaluation of such movements. Further studies are needed to validate this method in patients.

  12. Theoretical Model for Volume Fraction of UC, 235U Enrichment, and Effective Density of Final U 10Mo Alloy

    Energy Technology Data Exchange (ETDEWEB)

    Devaraj, Arun [Pacific Northwest National Lab. (PNNL), Richland, WA (United States). Environmental Molecular Sciences Lab. (EMSL); Prabhakaran, Ramprashad [Pacific Northwest National Lab. (PNNL), Richland, WA (United States). Environmental Molecular Sciences Lab. (EMSL); Joshi, Vineet V. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States). Environmental Molecular Sciences Lab. (EMSL); Hu, Shenyang Y. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States). Environmental Molecular Sciences Lab. (EMSL); McGarrah, Eric J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States). Environmental Molecular Sciences Lab. (EMSL); Lavender, Curt A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States). Environmental Molecular Sciences Lab. (EMSL)

    2016-04-12

    The purpose of this document is to provide a theoretical framework for (1) estimating uranium carbide (UC) volume fraction in a final alloy of uranium with 10 weight percent molybdenum (U-10Mo) as a function of final alloy carbon concentration, and (2) estimating effective 235U enrichment in the U-10Mo matrix after accounting for loss of 235U in forming UC. This report will also serve as a theoretical baseline for effective density of as-cast low-enriched U-10Mo alloy. Therefore, this report will serve as the baseline for quality control of final alloy carbon content

  13. Dual-mixed finite elements for the three-field Stokes model as a finite volume method on staggered grids

    KAUST Repository

    Kou, Jisheng

    2017-06-09

    In this paper, a new three-field weak formulation for Stokes problems is developed, and from this, a dual-mixed finite element method is proposed on a rectangular mesh. In the proposed mixed methods, the components of stress tensor are approximated by piecewise constant functions or Q1 functions, while the velocity and pressure are discretized by the lowest-order Raviart-Thomas element and the piecewise constant functions, respectively. Using quadrature rules, we demonstrate that this scheme can be reduced into a finite volume method on staggered grid, which is extensively used in computational fluid mechanics and engineering.

  14. Effect of metformin therapy on cardiac function and survival in a volume-overload model of heart failure in rats

    Czech Academy of Sciences Publication Activity Database

    Beneš, J.; Kazdová, L.; Drahota, Zdeněk; Houštěk, Josef; Medříková, Daša; Kopecký, Jan; Kovářová, Nikola; Vrbacký, Marek; Sedmera, David; Strnad, Hynek; Kolář, Michal; Petrák, J.; Benada, Oldřich; Škaroupková, P.; Červenka, L.; Melenovský, V.

    2011-01-01

    Roč. 121, č. 1 (2011), s. 29-41 ISSN 0143-5221 R&D Projects: GA MŠk(CZ) 1M0510; GA MZd(CZ) NS9757; GA MŠk(CZ) 1M0520 Grant - others:GA MZd(CZ) NS10497; GA ČR(CZ) GA305/09/1390 Institutional research plan: CEZ:AV0Z50110509; CEZ:AV0Z50520514; CEZ:AV0Z50200510 Keywords : AMP-activated protein kinase * energy metabolism * heart failure * metformin * survival * volume overload Subject RIV: FA - Cardiovascular Diseases incl. Cardiotharic Surgery Impact factor: 4.317, year: 2011

  15. Effects on Lung Function of Small-Volume Conventional Ventilation and High-Frequency Oscillatory Ventilation in a Model of Meconium Aspiration Syndrome.

    Science.gov (United States)

    Mikusiakova, L Tomcikova; Pistekova, H; Kosutova, P; Mikolka, P; Calkovska, A; Mokra, D

    2015-01-01

    For treatment of severe neonatal meconium aspiration syndrome (MAS), lung-protective mechanical ventilation is essential. This study compared short-term effects of small-volume conventional mechanical ventilation and high-frequency oscillatory ventilation on lung function in experimentally-induced MAS. In conventionally-ventilated rabbits, MAS was induced by intratracheal instillation of meconium suspension (4 ml/kg, 25 mg/ml). Then, animals were ventilated conventionally with small-volume (f-50/min; VT-6 ml/kg) or with high frequency ventilation (f-10/s) for 4 h, with the evaluation of blood gases, ventilatory pressures, and pulmonary shunts. After sacrifice, left lung was saline-lavaged and cells in bronchoalveolar lavage fluid (BALF) were determined. Right lung was used for the estimation of lung edema formation (wet/dry weight ratio). Thiobarbituric acid-reactive substances (TBARS), oxidative damage markers, were detected in lung tissue and plasma. Meconium instillation worsened gas exchange, and induced inflammation and lung edema. Within 4 h of ventilation, high frequency ventilation improved arterial pH and CO2 elimination compared with conventional ventilation. However, no other significant differences in oxygenation, ventilatory pressures, shunts, BALF cell counts, TBARS concentrations, or edema formation were observed between the two kinds of ventilation. We conclude that high frequency ventilation has only a slight advantage over small-volume conventional ventilation in the model of meconium aspiration syndrome in that it improves CO2 elimination.

  16. Renormalized Volume

    Science.gov (United States)

    Gover, A. Rod; Waldron, Andrew

    2017-09-01

    We develop a universal distributional calculus for regulated volumes of metrics that are suitably singular along hypersurfaces. When the hypersurface is a conformal infinity we give simple integrated distribution expressions for the divergences and anomaly of the regulated volume functional valid for any choice of regulator. For closed hypersurfaces or conformally compact geometries, methods from a previously developed boundary calculus for conformally compact manifolds can be applied to give explicit holographic formulæ for the divergences and anomaly expressed as hypersurface integrals over local quantities (the method also extends to non-closed hypersurfaces). The resulting anomaly does not depend on any particular choice of regulator, while the regulator dependence of the divergences is precisely captured by these formulæ. Conformal hypersurface invariants can be studied by demanding that the singular metric obey, smoothly and formally to a suitable order, a Yamabe type problem with boundary data along the conformal infinity. We prove that the volume anomaly for these singular Yamabe solutions is a conformally invariant integral of a local Q-curvature that generalizes the Branson Q-curvature by including data of the embedding. In each dimension this canonically defines a higher dimensional generalization of the Willmore energy/rigid string action. Recently, Graham proved that the first variation of the volume anomaly recovers the density obstructing smooth solutions to this singular Yamabe problem; we give a new proof of this result employing our boundary calculus. Physical applications of our results include studies of quantum corrections to entanglement entropies.

  17. Application of an unstructured 3D finite volume numerical model to flows and salinity dynamics in the San Francisco Bay-Delta

    Science.gov (United States)

    Martyr-Koller, R.C.; Kernkamp, H.W.J.; Van Dam, Anne A.; Mick van der Wegen,; Lucas, Lisa; Knowles, N.; Jaffe, B.; Fregoso, T.A.

    2017-01-01

    A linked modeling approach has been undertaken to understand the impacts of climate and infrastructure on aquatic ecology and water quality in the San Francisco Bay-Delta region. The Delft3D Flexible Mesh modeling suite is used in this effort for its 3D hydrodynamics, salinity, temperature and sediment dynamics, phytoplankton and water-quality coupling infrastructure, and linkage to a habitat suitability model. The hydrodynamic model component of the suite is D-Flow FM, a new 3D unstructured finite-volume model based on the Delft3D model. In this paper, D-Flow FM is applied to the San Francisco Bay-Delta to investigate tidal, seasonal and annual dynamics of water levels, river flows and salinity under historical environmental and infrastructural conditions. The model is driven by historical winds, tides, ocean salinity, and river flows, and includes federal, state, and local freshwater withdrawals, and regional gate and barrier operations. The model is calibrated over a 9-month period, and subsequently validated for water levels, flows, and 3D salinity dynamics over a 2 year period.Model performance was quantified using several model assessment metrics and visualized through target diagrams. These metrics indicate that the model accurately estimated water levels, flows, and salinity over wide-ranging tidal and fluvial conditions, and the model can be used to investigate detailed circulation and salinity patterns throughout the Bay-Delta. The hydrodynamics produced through this effort will be used to drive affiliated sediment, phytoplankton, and contaminant hindcast efforts and habitat suitability assessments for fish and bivalves. The modeling framework applied here will serve as a baseline to ultimately shed light on potential ecosystem change over the current century.

  18. Application of an unstructured 3D finite volume numerical model to flows and salinity dynamics in the San Francisco Bay-Delta

    Science.gov (United States)

    Martyr-Koller, R. C.; Kernkamp, H. W. J.; van Dam, A.; van der Wegen, M.; Lucas, L. V.; Knowles, N.; Jaffe, B.; Fregoso, T. A.

    2017-06-01

    A linked modeling approach has been undertaken to understand the impacts of climate and infrastructure on aquatic ecology and water quality in the San Francisco Bay-Delta region. The Delft3D Flexible Mesh modeling suite is used in this effort for its 3D hydrodynamics, salinity, temperature and sediment dynamics, phytoplankton and water-quality coupling infrastructure, and linkage to a habitat suitability model. The hydrodynamic model component of the suite is D-Flow FM, a new 3D unstructured finite-volume model based on the Delft3D model. In this paper, D-Flow FM is applied to the San Francisco Bay-Delta to investigate tidal, seasonal and annual dynamics of water levels, river flows and salinity under historical environmental and infrastructural conditions. The model is driven by historical winds, tides, ocean salinity, and river flows, and includes federal, state, and local freshwater withdrawals, and regional gate and barrier operations. The model is calibrated over a 9-month period, and subsequently validated for water levels, flows, and 3D salinity dynamics over a 2 year period. Model performance was quantified using several model assessment metrics and visualized through target diagrams. These metrics indicate that the model accurately estimated water levels, flows, and salinity over wide-ranging tidal and fluvial conditions, and the model can be used to investigate detailed circulation and salinity patterns throughout the Bay-Delta. The hydrodynamics produced through this effort will be used to drive affiliated sediment, phytoplankton, and contaminant hindcast efforts and habitat suitability assessments for fish and bivalves. The modeling framework applied here will serve as a baseline to ultimately shed light on potential ecosystem change over the current century.

  19. Study of the relationship between the target tissue necrosis volume and the target tissue size in liver tumours using two-compartment finite element RFA modelling.

    Science.gov (United States)

    Zhang, Bing; Moser, Michael A J; Zhang, Edwin M; Luo, Yigang; Zhang, Hongbo; Zhang, Wenjun

    2014-12-01

    The aim of this study was to investigate the relationship between the target tissue necrosis volume and the target tissue size during the radiofrequency ablation (RFA) procedure. The target tissues with four different sizes (dxy = 20, 25, 30 and 35 mm) were modelled using a two-compartment radiofrequency ablation model. Different voltages were applied to seek the maximum target tissue necrosis volume for each target tissue size. The first roll-off occurrence or the standard ablation time (12 min) was taken as the sign for the termination of the RFA procedure. Four different maximum voltages without the roll-off occurrence were found for the four different sizes of target tissues (dxy = 20, 25, 30 and 35 mm), and they were 36.6, 35.4, 33.9 and 32.5 V, respectively. The target tissues with diameters of 20, 25 mm can be cleanly ablated at their own maximum voltages applied (MVA) but the same finding was not found for the 35-mm target tissue. For the target tissue with diameter of 30 mm, the 50 °C isothermal contour (IT50) result showed that the target tissue can be cleanly ablated, but the same result did not show in the Arrhenius damage model result. Furthermore, two optimal RFA protocols with a minimal thermal damage to the healthy tissues were found for the target tissues with diameters of 20 and 25 mm, respectively. The study suggests that target tissues of different sizes should be treated with different RFA protocols. The maximum target tissue volume was achieved with the MVA without the roll-off occurrence for each target tissue size when a constant RF power supply was used.

  20. (Liquid plus liquid) equilibria of binary polymer solutions using a free-volume UNIQUAC-NRF model

    DEFF Research Database (Denmark)

    Radfarnia, H.R.; Ghotbi, C.; Taghikhani, V.

    2006-01-01

    + liquid) equilibria (LLE) for a number of binary polymer solutions at various temperatures. The values for the binary characteristic energy parameters for the proposed model and the FV-UNIQUAC model along with their average relative deviations from the experimental data were reported. It should be stated...... that the binary polymer solutions studied in this work were considered as monodisperse. The results obtained from the FV-UNIQUAC-NRF model were compared with those obtained from the FV-UNIQUAC model. The results of the proposed model show that the FV-UNIQUAC-NRF model can accurately correlate the experimental...... in predicting the LCST for binary polymer solutions....

  1. A new turbine model for enhancing convective heat transfer in the presence of low volume concentration of Ag-Oil Nanofluids

    Science.gov (United States)

    Jafarimoghaddam, Amin; Aberoumand, Sadegh; Jafarimoghaddam, Reza

    2018-05-01

    This study aims to experimentally investigate and introduce a new model for enhancing convective heat transfer in the presence of Ag/ oil nanofluid. An annular tube was designed with a turbine element attached to the inner tube. The inner tube was a bearing shaft which could rotate with the rotation of turbine element. As the previous works by authors, the setup was conducted with a fully developed laminar flow regime with the Reynolds numbers less than 160. The outer surface of the annular tube was heated by an element with constant heat flux of 204 W. Ag/ oil nanofluid was used in different volume concentrations of 0.011%, 0.044% and 0.171%. The new model could enhance the convective heat transfer coefficient up to 54% (compared to the simple annular tube in the case of base fluid) for the best studied case (nanofluid with the volume concentration of 0.171%) while the friction factor remained low. The new model can be applied for related applications regarding Ag/ oil nanofluid as a new step in enhancing the convective heat transfer coefficient.

  2. A two-phase debris-flow model that includes coupled evolution of volume fractions, granular dilatancy, and pore-fluid pressure

    Science.gov (United States)

    George, David L.; Iverson, Richard M.

    2011-01-01

    Pore-fluid pressure plays a crucial role in debris flows because it counteracts normal stresses at grain contacts and thereby reduces intergranular friction. Pore-pressure feedback accompanying debris deformation is particularly important during the onset of debrisflow motion, when it can dramatically influence the balance of forces governing downslope acceleration. We consider further effects of this feedback by formulating a new, depth-averaged mathematical model that simulates coupled evolution of granular dilatancy, solid and fluid volume fractions, pore-fluid pressure, and flow depth and velocity during all stages of debris-flow motion. To illustrate implications of the model, we use a finite-volume method to compute one-dimensional motion of a debris flow descending a rigid, uniformly inclined slope, and we compare model predictions with data obtained in large-scale experiments at the USGS debris-flow flume. Predictions for the first 1 s of motion show that increasing pore pressures (due to debris contraction) cause liquefaction that enhances flow acceleration. As acceleration continues, however, debris dilation causes dissipation of pore pressures, and this dissipation helps stabilize debris-flow motion. Our numerical predictions of this process match experimental data reasonably well, but predictions might be improved by accounting for the effects of grain-size segregation.

  3. A new turbine model for enhancing convective heat transfer in the presence of low volume concentration of Ag-Oil Nanofluids

    Science.gov (United States)

    Jafarimoghaddam, Amin; Aberoumand, Sadegh; Jafarimoghaddam, Reza

    2017-12-01

    This study aims to experimentally investigate and introduce a new model for enhancing convective heat transfer in the presence of Ag/ oil nanofluid. An annular tube was designed with a turbine element attached to the inner tube. The inner tube was a bearing shaft which could rotate with the rotation of turbine element. As the previous works by authors, the setup was conducted with a fully developed laminar flow regime with the Reynolds numbers less than 160. The outer surface of the annular tube was heated by an element with constant heat flux of 204 W. Ag/ oil nanofluid was used in different volume concentrations of 0.011%, 0.044% and 0.171%. The new model could enhance the convective heat transfer coefficient up to 54% (compared to the simple annular tube in the case of base fluid) for the best studied case (nanofluid with the volume concentration of 0.171%) while the friction factor remained low. The new model can be applied for related applications regarding Ag/ oil nanofluid as a new step in enhancing the convective heat transfer coefficient.

  4. Analysis of the forced vibration test of the Hualien large scale soil-structure interaction model using a flexible volume substructuring method

    International Nuclear Information System (INIS)

    Tang, H.T.; Nakamura, N.

    1995-01-01

    A 1/4-scale cylindrical reactor containment model was constructed in Hualien, Taiwan for foil-structure interaction (SSI) effect evaluation and SSI analysis procedure verification. Forced vibration tests were executed before backfill (FVT-1) and after backfill (FVT-2) to characterize soil-structure system characteristics under low excitations. A number of organizations participated in the pre-test blind prediction and post-test correlation analyses of the forced vibration test using various industry familiar methods. In the current study, correlation analyses were performed using a three-dimensional flexible volume substructuring method. The results are reported and soil property sensitivities are evaluated in the paper. (J.P.N.)

  5. Ecosystem models. Volume 3. November, 1977--October, 1978 (a bibliography with abstracts). Report for Nov 1977--Oct 1978

    International Nuclear Information System (INIS)

    Harrison, E.A.

    1978-10-01

    The preparation and use of ecosystem models are covered in this bibliography of Federally-funded research. Models for marine biology, wildlife, plants, water pollution, microorganisms, food chains, radioactive substances, limnology, and diseases as related to ecosystems are included

  6. Global ice volume variations through the last glacial cycle simulated by a 3-D ice-dynamical model

    NARCIS (Netherlands)

    Bintanja, R.; Wal, R.S.W. van de; Oerlemans, J.

    2002-01-01

    A coupled ice sheet—ice shelf—bedrock model was run at 20km resolution to simulate the evolution of global ice cover during the last glacial cycle. The mass balance model uses monthly mean temperature and precipitation as input and incorporates the albedo—mass balance feedback. The model is forced

  7. Industrial Sector Technology Use Model (ISTUM): industrial energy use in the United States, 1974-2000. Volume 1: primary model documentation, Book 2, Chapters IV, V, VI, and VII

    Energy Technology Data Exchange (ETDEWEB)

    Bohn, R.E.; Herod, J.S.

    1978-06-19

    The Industrial Sector Technology Use Model provides a single framework for integrating all of the information and analysis into a set of predictions of industrial energy use. Given this volume of information which must be considered, this requires a set of computerized engineering-economic models. The design of these models is the subject of Chapter IV. The environmental factors in ISTUM are developed and presented in Chapter V. Chapter VI discusses the work accomplished by DATA Resources, Inc. in support of the ISTUM. A glossary, briefly defining special terms used in the ISTUM documentation, is given in Chapter VII. (MCW)

  8. Black liquor combustion validated recovery boiler modeling: Final year report. Volume 1 (Main text and Appendix I, sections 1--4)

    Energy Technology Data Exchange (ETDEWEB)

    Grace, T.M.; Frederick, W.J.; Salcudean, M.; Wessel, R.A.

    1998-08-01

    This project was initiated in October 1990, with the objective of developing and validating a new computer model of a recovery boiler furnace using a computational fluid dynamics (CFD) code specifically tailored to the requirements for solving recovery boiler flows, and using improved submodels for black liquor combustion based on continued laboratory fundamental studies. The key tasks to be accomplished were as follows: (1) Complete the development of enhanced furnace models that have the capability to accurately predict carryover, emissions behavior, dust concentrations, gas temperatures, and wall heat fluxes. (2) Validate the enhanced furnace models, so that users can have confidence in the predicted results. (3) Obtain fundamental information on aerosol formation, deposition, and hardening so as to develop the knowledge base needed to relate furnace model outputs to plugging and fouling in the convective sections of the boiler. (4) Facilitate the transfer of codes, black liquid submodels, and fundamental knowledge to the US kraft pulp industry. Volume 1 contains the main body of the report and the first 4 sections of Appendix 1: Modeling of black liquor recovery boilers -- summary report; Flow and heat transfer modeling in the upper furnace of a kraft recovery boiler; Numerical simulation of black liquor combustion; and Investigation of turbulence models and prediction of swirling flows for kraft recovery furnaces.

  9. Comparison of distinctive models for calculating an interlobar emphysema heterogeneity index in patients prior to endoscopic lung volume reduction

    Directory of Open Access Journals (Sweden)

    Theilig D

    2017-06-01

    Full Text Available Dorothea Theilig,1 Felix Doellinger,1 Alexander Poellinger,1 Vera Schreiter,1 Konrad Neumann,2 Ralf-Harto Hubner31Department of Radiology, Charité Campus Virchow Klinikum, Charité, Universitätsmedizin Berlin, Berlin, Germany; 2Institute of Biometrics and Clinical Epidemiology, Charité Campus Benjamin Franklin, Charité, Universitätsmedizin Berlin, Berlin, Germany; 3Department of Pneumology, Charité Campus Virchow Klinikum, Charité, Universitätsmedizin Berlin, Berlin, GermanyBackground: The degree of interlobar emphysema heterogeneity is thought to play an important role in the outcome of endoscopic lung volume reduction (ELVR therapy of patients with advanced COPD. There are multiple ways one could possibly define interlobar emphysema heterogeneity, and there is no standardized definition.Purpose: The aim of this study was to derive a formula for calculating an interlobar emphysema heterogeneity index (HI when evaluating a patient for ELVR. Furthermore, an attempt was made to identify a threshold for relevant interlobar emphysema heterogeneity with regard to ELVR.Patients and methods: We retrospectively analyzed 50 patients who had undergone technically successful ELVR with placement of one-way valves at our institution and had received lung function tests and computed tomography scans before and after treatment. Predictive accuracy of the different methods for HI calculation was assessed with receiver-operating characteristic curve analysis, assuming a minimum difference in forced expiratory volume in 1 second of 100 mL to indicate a clinically important change.Results: The HI defined as emphysema score of the targeted lobe (TL minus emphysema score of the ipsilateral nontargeted lobe disregarding the middle lobe yielded the best predicative accuracy (AUC =0.73, P=0.008. The HI defined as emphysema score of the TL minus emphysema score of the lung without the TL showed a similarly good predictive accuracy (AUC =0.72, P=0.009. Subgroup

  10. Civilian use transport of radioactive substances on public road. Volume 1: Shipment accreditation and approval requests. Guide Nr 7, Revision 2 of 15 February 2016. Volume 2: safety file of package models, European guide 'Package Design Safety Report'. Civilian use transport of radioactive packages or substances on public road. Volume 3: Compliance of package models not subject to accreditation. Guide Nr 7, Revision 7 of the 2015/11/13

    International Nuclear Information System (INIS)

    2016-01-01

    After having recalled the regulatory context and sanctions susceptible to be applied, the first volume presents the accreditation process for a package model: file content, tests programme, safety file, certification studies, documents to be produced, accreditation prorogation request, accreditation extension or package model modifications, instruction delays. Some peculiar cases are described. Models of accreditation certificate are provided, and obligations concerning packaging design, fabrication, use and maintenance are briefly discussed. The second volume is a European technical guide which is intended to assist in the preparation of the Package Design Safety Report (PDSR) to demonstrate compliance of a package design for the transport of radioactive material with the regulatory requirements. It covers package designs requiring competent authority approval, and also covers package designs not requiring competent authority approval. In its first two chapters, this document provides a generic structure and contents of a PDSR which applies to all package types. The contents are described in a comprehensive way to cover all important aspects. Some of these aspects may not be applicable to specific package type and details can be found in the annexes which provide further guidance for the scope of the contents of a PDSR, specifically for each package type. The third volume presents recommendations made by the ASN for all stakeholders to guarantee the compliance to regulation of package models which are 'not submitted to competent authority approval'. After an indication and a comment of the regulatory context, it presents requirements to be applied for the design of those package models, and then describes and comments the structure and content of a safety file for such package models (generalities, authorised contents, packaging description, safety demonstration, receipt, use and maintenance instruction, management system). The last part presents the

  11. Eocene to mid-Pliocene landscape evolution in Scandinavia inferred from offshore sediment volumes and pre-glacial topography using inverse modelling

    Science.gov (United States)

    Pedersen, Vivi K.; Braun, Jean; Huismans, Ritske S.

    2018-02-01

    The origin of high topography in Scandinavia is highly debated, both in terms of its age and the underlying mechanism for its formation. Traditionally, the current high to