WorldWideScience

Sample records for modeling procedure results

  1. Model of Procedure Usage – Results from a Qualitative Study to Inform Design of Computer-Based Procedures

    Energy Technology Data Exchange (ETDEWEB)

    Johanna H Oxstrand; Katya L Le Blanc

    2012-07-01

    The nuclear industry is constantly trying to find ways to decrease the human error rate, especially the human errors associated with procedure use. As a step toward the goal of improving procedure use performance, researchers, together with the nuclear industry, have been looking at replacing the current paper-based procedures with computer-based procedure systems. The concept of computer-based procedures is not new by any means; however most research has focused on procedures used in the main control room. Procedures reviewed in these efforts are mainly emergency operating procedures and normal operating procedures. Based on lessons learned for these previous efforts we are now exploring a more unknown application for computer based procedures - field procedures, i.e. procedures used by nuclear equipment operators and maintenance technicians. The Idaho National Laboratory, the Institute for Energy Technology, and participants from the U.S. commercial nuclear industry are collaborating in an applied research effort with the objective of developing requirements and specifications for a computer-based procedure system to be used by field operators. The goal is to identify the types of human errors that can be mitigated by using computer-based procedures and how to best design the computer-based procedures to do this. The underlying philosophy in the research effort is “Stop – Start – Continue”, i.e. what features from the use of paper-based procedures should we not incorporate (Stop), what should we keep (Continue), and what new features or work processes should be added (Start). One step in identifying the Stop – Start – Continue was to conduct a baseline study where affordances related to the current usage of paper-based procedures were identified. The purpose of the study was to develop a model of paper based procedure use which will help to identify desirable features for computer based procedure prototypes. Affordances such as note taking, markups

  2. MITG test procedure and results

    International Nuclear Information System (INIS)

    Eck, M.E.; Mukunda, M.

    1983-01-01

    Elements and modules for Radioisotope Thermoelectric Generator have been performance tested since the inception of the RTG program. These test articles seldom resembled flight hardware and often lacked adequate diagnostic instrumentation. Because of this, performance problems were not identified in the early stage of program development. The lack of test data in an unexpected area often hampered the development of a problem solution. A procedure for conducting the MITG Test was developed in an effort to obtain data in a systematic, unambiguous manner. This procedure required the development of extensive data acquisition software and test automation. The development of a facility to implement the test procedure, the facility hardware and software requirements, and the results of the MITG testing are the subject of this paper

  3. Models and procedures for interval evaluating the results of control of knowledge in computer systems testing of Navy

    Directory of Open Access Journals (Sweden)

    D. A. Pechnikov

    2018-01-01

    Full Text Available To implement effective military and professional training of Navy specialists, a corresponding educational and material base is needed. As a result of the reduction in the 1990s in the branches of the military-industrial complex developing weapons and equipment for the Navy, the latest models of this technology are now produced not in batches, but in individual copies. The question of the production of training and training samples is not worth it at all. Under these conditions, only virtual analogues of military equipment and weapons, developed by means of information technology, i.e., training and training systems (TOS, can be considered as the only means capable of providing military-professional training. At the modern level of the development of information technologies, testing is the only universal technical means of monitoring the knowledge of students. Procedures for knowledge control in modern computer testing systems do not meet the requirements for them according to the following characteristics: 1 the absence of the possibility of evaluating the error of the test results; 2 the absence of the possibility of stopping testing when the specified reliability of its results is achieved. In order to effectively implement the means of operational criteria-based pedagogical control of knowledge in the process of training specialists of the Navy and to enable joint analysis and processing of evaluations of learning outcomes, it is advisable to implement the following practical recommendations: 1. Formulating the teacher's preferences system regarding the quality of trainee training and the teacher's preferences system in relation to The significance of single test tasks in the test should be considered as the most important The essential steps in preparing a test for practical use. 2. The teacher who first enters the input of his preference systems should check their actual compliance on a sample of 5-10 such test results that cover the full

  4. TESTING THE ASSUMPTIONS AND INTERPRETING THE RESULTS OF THE RASCH MODEL USING LOG-LINEAR PROCEDURES IN SPSS

    NARCIS (Netherlands)

    TENVERGERT, E; GILLESPIE, M; KINGMA, J

    This paper shows how to use the log-linear subroutine of SPSS to fit the Rasch model. It also shows how to fit less restrictive models obtained by relaxing specific assumptions of the Rasch model. Conditional maximum likelihood estimation was achieved by including dummy variables for the total

  5. Trapezio-metacarpal arthrodesis: procedure and results.

    Science.gov (United States)

    Galán, Adolfo; Arenas, Javier R; del Águila, Belén; Guerado, Enrique; Andrés-Cano, Pablo

    2015-04-01

    meet previous expectations. On the radiographic evaluation, consolidation has been achieved in 17 patients. When thumb carpo-metacarpal arthrodesis is indicated, the procedure provides a reliable and lasting treatment with satisfactory results. The development of new implants and the possibility of introducing autologous graft percutaneously as is described using this technique leads to improve the results.

  6. Typical NRC inspection procedures for model plant

    International Nuclear Information System (INIS)

    Blaylock, J.

    1984-01-01

    A summary of NRC inspection procedures for a model LEU fuel fabrication plant is presented. Procedures and methods for combining inventory data, seals, measurement techniques, and statistical analysis are emphasized

  7. Atmospheric Deposition Modeling Results

    Data.gov (United States)

    U.S. Environmental Protection Agency — This asset provides data on model results for dry and total deposition of sulfur, nitrogen and base cation species. Components include deposition velocities, dry...

  8. Random effect modelling of patient-related risk factors in orthopaedic procedures: results from the Dutch nosocomial infection surveillance network 'PREZIES'.

    NARCIS (Netherlands)

    Muilwijk, J; Walenkamp, G H I M; Voss, Andreas; Wille, Jan C; Hof, Susan van den

    2006-01-01

    In the Dutch surveillance for surgical site infections (SSIs), data from 70277 orthopaedic procedures with 1895 SSIs were collected between 1996 and 2003. The aims of this study were: (1) to analyse the trends in SSIs associated with Gram-positive and Gram-negative bacteria; (2) to estimate

  9. Procedural Personas for Player Decision Modeling and Procedural Content Generation

    DEFF Research Database (Denmark)

    Holmgård, Christoffer

    2016-01-01

    ." These methods for constructing procedural personas are then integrated with existing procedural content generation systems, acting as critics that shape the output of these systems, optimizing generated content for different personas and by extension, different kinds of players and their decision making styles......How can player models and artificially intelligent (AI) agents be useful in early-stage iterative game and simulation design? One answer may be as ways of generating synthetic play-test data, before a game or level has ever seen a player, or when the sampled amount of play test data is very low....... This thesis explores methods for creating low-complexity, easily interpretable, generative AI agents for use in game and simulation design. Based on insights from decision theory and behavioral economics, the thesis investigates how player decision making styles may be defined, operationalised, and measured...

  10. A model of procedural and distributive fairness

    NARCIS (Netherlands)

    Krawczyk, M.W.

    2007-01-01

    This paper presents a new model aimed at predicting behav- ior in games involving a randomized allocation procedure. It is designed to capture the relative importance and interaction between procedural justice (defined crudely in terms of the share of one's expected outcome in the sum of all

  11. Robust estimation procedure in panel data model

    Energy Technology Data Exchange (ETDEWEB)

    Shariff, Nurul Sima Mohamad [Faculty of Science of Technology, Universiti Sains Islam Malaysia (USIM), 71800, Nilai, Negeri Sembilan (Malaysia); Hamzah, Nor Aishah [Institute of Mathematical Sciences, Universiti Malaya, 50630, Kuala Lumpur (Malaysia)

    2014-06-19

    The panel data modeling has received a great attention in econometric research recently. This is due to the availability of data sources and the interest to study cross sections of individuals observed over time. However, the problems may arise in modeling the panel in the presence of cross sectional dependence and outliers. Even though there are few methods that take into consideration the presence of cross sectional dependence in the panel, the methods may provide inconsistent parameter estimates and inferences when outliers occur in the panel. As such, an alternative method that is robust to outliers and cross sectional dependence is introduced in this paper. The properties and construction of the confidence interval for the parameter estimates are also considered in this paper. The robustness of the procedure is investigated and comparisons are made to the existing method via simulation studies. Our results have shown that robust approach is able to produce an accurate and reliable parameter estimates under the condition considered.

  12. Early changes in experimental osteoarthritis using the Pond-Nuki dog model: technical procedure and initial results of in vivo MR imaging

    Energy Technology Data Exchange (ETDEWEB)

    Libicher, Martin [University of Heidelberg, Department of Radiology, Heidelberg (Germany); Ivancic, Mate; Hoffmann, Volker; Wenz, Wolfram [University of Heidelberg, Department of Orthopaedics, Heidelberg (Germany)

    2005-02-01

    The purpose of this study was to prove the feasibility of combining in vivo MR imaging with the Pond-Nuki animal model for the evaluation of osteoarthritis. In an experimental study, 24 beagle dogs underwent transection of the anterior cruciate ligament of the left leg (modified Pond-Nuki model). The dogs were randomly assigned into four groups and examined by MRI after 6, 12, 24 and 48 weeks. MR imaging of both knees was performed under general anesthesia with the contralateral joint serving as control. In group 1 (6 weeks postoperatively), the first sign detected on MRI was subchondral bone marrow edema in the posteromedial tibia. After 12 weeks, erosion of the posteromedial tibial cartilage could be observed, followed by meniscus degeneration and osteophytosis after 24 and 48 weeks. The contralateral knee joint showed transient joint effusion, but no significant signs of internal derangement (P<0.001). By combining in vivo MR imaging with the Pond-Nuki model, it is possible to detect early signs of osteoarthritis. The first sign was posteromedial subchondral bone marrow edema in the tibia followed by progressive cartilage degeneration and joint derangement. The in vivo model therefore seems to be suitable for longitudinal studies or monitoring the therapeutic effects of osteoarthritis. (orig.)

  13. Procedural Modeling for Digital Cultural Heritage

    Directory of Open Access Journals (Sweden)

    Müller Pascal

    2009-01-01

    Full Text Available The rapid development of computer graphics and imaging provides the modern archeologist with several tools to realistically model and visualize archeological sites in 3D. This, however, creates a tension between veridical and realistic modeling. Visually compelling models may lead people to falsely believe that there exists very precise knowledge about the past appearance of a site. In order to make the underlying uncertainty visible, it has been proposed to encode this uncertainty with different levels of transparency in the rendering, or of decoloration of the textures. We argue that procedural modeling technology based on shape grammars provides an interesting alternative to such measures, as they tend to spoil the experience for the observer. Both its efficiency and compactness make procedural modeling a tool to produce multiple models, which together sample the space of possibilities. Variations between the different models express levels of uncertainty implicitly, while letting each individual model keeping its realistic appearance. The underlying, structural description makes the uncertainty explicit. Additionally, procedural modeling also yields the flexibility to incorporate changes as knowledge of an archeological site gets refined. Annotations explaining modeling decisions can be included. We demonstrate our procedural modeling implementation with several recent examples.

  14. A procedure for building product models

    DEFF Research Database (Denmark)

    Hvam, Lars; Riis, Jesper; Malis, Martin

    2001-01-01

    This article presents a procedure for building product models to support the specification processes dealing with sales, design of product variants and production preparation. The procedure includes, as the first phase, an analysis and redesign of the business processes, which are to be supported...... with product models. The next phase includes an analysis of the product assortment, and the set up of a so-called product master. Finally the product model is designed and implemented using object oriented modelling. The procedure is developed in order to ensure that the product models constructed are fit...... for the business processes they support, and properly structured and documented, in order to facilitate that the systems can be maintained continually and further developed. The research has been carried out at the Centre for Industrialisation of Engineering, Department of Manufacturing Engineering, Technical...

  15. Improvement and Validation of Weld Residual Stress Modelling Procedure

    International Nuclear Information System (INIS)

    Zang, Weilin; Gunnars, Jens; Dong, Pingsha; Hong, Jeong K.

    2009-06-01

    The objective of this work is to identify and evaluate improvements for the residual stress modelling procedure currently used in Sweden. There is a growing demand to eliminate any unnecessary conservatism involved in residual stress assumptions. The study was focused on the development and validation of an improved weld residual stress modelling procedure, by taking advantage of the recent advances in residual stress modelling and stress measurement techniques. The major changes applied in the new weld residual stress modelling procedure are: - Improved procedure for heat source calibration based on use of analytical solutions. - Use of an isotropic hardening model where mixed hardening data is not available. - Use of an annealing model for improved simulation of strain relaxation in re-heated material. The new modelling procedure is demonstrated to capture the main characteristics of the through thickness stress distributions by validation to experimental measurements. Three austenitic stainless steel butt-welds cases are analysed, covering a large range of pipe geometries. From the cases it is evident that there can be large differences between the residual stresses predicted using the new procedure, and the earlier procedure or handbook recommendations. Previously recommended profiles could give misleading fracture assessment results. The stress profiles according to the new procedure agree well with the measured data. If data is available then a mixed hardening model should be used

  16. Results of a national survey on nuclear medicine procedures

    International Nuclear Information System (INIS)

    Curti, A.R.; Gatica, N.A.; Melis, H.J.

    1998-01-01

    Full text: In 1997, the Nuclear Regulatory Authority of Argentina carried out a compilation of data on radiopharmaceuticals administered to patients in nuclear medicine procedures. Its aim was to get information on the radiopharmaceuticals that are used in different procedures and the activity administered to the patient, to assess the radiation exposure of the population and to contribute to a global survey of medical radiation usage and exposures conducted by the United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR), by sending information of the country. The data compiled were analysed, and for the most frequent procedures, the mean activity administered, the standard deviation, the distribution of the number of procedures for different age groups, sex and radiopharmaceuticals were assessed. The radiation exposure for children and adults was estimated. For the main diagnostic examinations, the results of the survey were compared with specific values published in the Basic Safety Standards of the International Atomic Energy Agency (Safety Series No. 115, 1996). As a conclusion, it may be point out the importance of continuing with the compilation of this kind of information in order to identify emerging trends on the use of nuclear medicine procedures in Argentina and the activity of radiopharmaceuticals administered to the patients. (author) [es

  17. [Results of an experience with the Bentall procedure].

    Science.gov (United States)

    Gallego, Javier; Ferreira, R; Roque, J; Guerra, N; Gennari, M; Serpa, C; Mendes, S; Mendes, M; Lucero, R; Lemos, A; Pereira, R; Nobre, A; Cravino, J

    2008-01-01

    The authors report a retrospective study of patients who underwent a Bentall procedure in the Cardio-Thoracic Surgery Department of Hospital Santa Maria, Lisbon. Data were obtained from 42 patients who underwent the Bentall procedure between 1991 and 2008. Different parameters were compared as well as the short and long term results. The median age was 58,5 years being 88% of patients of male gender. 32 (76,27%) presented with ascending aorta degenerative aneurism, 6 p (14,3%) with type A aortic dissection and 4p (9,5%) with Marfan syndrome. 10p(23.8%) had associated coronary artery disease and there were 6p (14.3%) who underwent emergency surgery. Among the risk factors associated, 24 p (57,1%) had hypertension, 12 p (28,6%) dyslipidemia, 4p (9,5%) had history of smoking, 7 p (16,7%) diabetes, 6 p (14,3%) CPOD, 2 p (4,8%) renal dysfunction and 2 had a recent myocardial infarction. There were 7p (16,7%) with left ventricular dysfunction (EFBentall procedure obtained good results in short and long term and, despite the emerging of new and more complex techniques like remodelling and reimplantation, our results support the maintenance of this procedure as the preferential treatment for aortic root and valvular disease.

  18. On the general procedure for modelling complex ecological systems

    International Nuclear Information System (INIS)

    He Shanyu.

    1987-12-01

    In this paper, the principle of a general procedure for modelling complex ecological systems, i.e. the Adaptive Superposition Procedure (ASP) is shortly stated. The result of application of ASP in a national project for ecological regionalization is also described. (author). 3 refs

  19. On Realism of Architectural Procedural Models

    Czech Academy of Sciences Publication Activity Database

    Beneš, J.; Kelly, T.; Děchtěrenko, Filip; Křivánek, J.; Müller, P.

    2017-01-01

    Roč. 36, č. 2 (2017), s. 225-234 ISSN 0167-7055 Grant - others:AV ČR(CZ) StrategieAV21/14 Program:StrategieAV Institutional support: RVO:68081740 Keywords : realism * procedural modeling * architecture Subject RIV: IN - Informatics, Computer Science Impact factor: 1.611, year: 2016

  20. On Realism of Architectural Procedural Models

    Czech Academy of Sciences Publication Activity Database

    Beneš, J.; Kelly, T.; Děchtěrenko, Filip; Křivánek, J.; Müller, P.

    2017-01-01

    Roč. 36, č. 2 (2017), s. 225-234 ISSN 0167-7055 Grant - others:AV ČR(CZ) StrategieAV21/14 Program:StrategieAV Institutional support: RVO:68081740 Keywords : realism * procedural modeling * architecture Subject RIV: IN - Informatics, Computer Science OBOR OECD: Cognitive sciences Impact factor: 1.611, year: 2016

  1. Shape Synthesis from Sketches via Procedural Models and Convolutional Networks.

    Science.gov (United States)

    Huang, Haibin; Kalogerakis, Evangelos; Yumer, Ersin; Mech, Radomir

    2017-08-01

    Procedural modeling techniques can produce high quality visual content through complex rule sets. However, controlling the outputs of these techniques for design purposes is often notoriously difficult for users due to the large number of parameters involved in these rule sets and also their non-linear relationship to the resulting content. To circumvent this problem, we present a sketch-based approach to procedural modeling. Given an approximate and abstract hand-drawn 2D sketch provided by a user, our algorithm automatically computes a set of procedural model parameters, which in turn yield multiple, detailed output shapes that resemble the user's input sketch. The user can then select an output shape, or further modify the sketch to explore alternative ones. At the heart of our approach is a deep Convolutional Neural Network (CNN) that is trained to map sketches to procedural model parameters. The network is trained by large amounts of automatically generated synthetic line drawings. By using an intuitive medium, i.e., freehand sketching as input, users are set free from manually adjusting procedural model parameters, yet they are still able to create high quality content. We demonstrate the accuracy and efficacy of our method in a variety of procedural modeling scenarios including design of man-made and organic shapes.

  2. New procedure for declaring accidents resulting in bodily injuries

    CERN Multimedia

    2014-01-01

    The HR Department would like to remind members of personnel that, according to Administrative Circular No. 14 (Rev. 3), entitled “Protection of members of the personnel against the financial consequences of illness, accident and incapacity for work”, accidents resulting in bodily injuries and presumed to be of an occupational nature should, under normal circumstances, be declared within 10 working days of the accident having occurred, accompanied by a medical certificate. In an effort to streamline procedures, occupational accident declarations should be made via EDH using the “declaration of occupational accident” electronic form. For the declaration of non-occupational accidents resulting in bodily injuries of members of the CERN Health Insurance Scheme (CHIS), a new paper form has been elaborated that can be downloaded from the CHIS website and is also available from the UNIQA Helpdesk in the Main Building. If you encounter technical difficulties with these new ...

  3. Procedural Content Graphs for Urban Modeling

    Directory of Open Access Journals (Sweden)

    Pedro Brandão Silva

    2015-01-01

    Full Text Available Massive procedural content creation, for example, for virtual urban environments, is a difficult, yet important challenge. While shape grammars are a popular example of effectiveness in architectural modeling, they have clear limitations regarding readability, manageability, and expressive power when addressing a variety of complex structural designs. Moreover, shape grammars aim at geometry specification and do not facilitate integration with other types of content, such as textures or light sources, which could rather accompany the generation process. We present procedural content graphs, a graph-based solution for procedural generation that addresses all these issues in a visual, flexible, and more expressive manner. Besides integrating handling of diverse types of content, this approach introduces collective entity manipulation as lists, seamlessly providing features such as advanced filtering, grouping, merging, ordering, and aggregation, essentially unavailable in shape grammars. Hereby, separated entities can be easily merged or just analyzed together in order to perform a variety of context-based decisions and operations. The advantages of this approach are illustrated via examples of tasks that are either very cumbersome or simply impossible to express with previous grammar approaches.

  4. On Using Selection Procedures with Binomial Models.

    Science.gov (United States)

    1983-10-01

    eds.), Shinko Tsusho Co. Ltd., Tokyo, Japan , pp. 501-533. Gupta, S. S. and Sobel, M. (1960). Selecting a subset containing the best of several...IA_____3_6r__I____ *TITLE food A$ieweI L TYPE of 09PORT 6 PERIOD COVERED ON USING SELECTION PROCEDURES WITH BINOMIAL MODELS Technical 6. PeSPRFeauS1 ONG. REPORT...ontoedis stoc toeSI. to Ei.,..,t&* toemR.,. 14. SUPPOLEMENTARY MOCTES 19. Rey WORDS (Coatiou. 40 ow.oa* edo if Necesary and #do""&a by block number

  5. Expose : procedure and results of the joint experiment verification tests

    Science.gov (United States)

    Panitz, C.; Rettberg, P.; Horneck, G.; Rabbow, E.; Baglioni, P.

    The International Space Station will carry the EXPOSE facility accommodated at the universal workplace URM-D located outside the Russian Service Module. The launch will be affected in 2005 and it is planned to stay in space for 1.5 years. The tray like structure will accomodate 2 chemical and 6 biological PI-experiments or experiment systems of the ROSE (Response of Organisms to Space Environment) consortium. EXPOSE will support long-term in situ studies of microbes in artificial meteorites, as well as of microbial communities from special ecological niches, such as endolithic and evaporitic ecosystems. The either vented or sealed experiment pockets will be covered by an optical filter system to control intensity and spectral range of solar UV irradiation. Control of sun exposure will be achieved by the use of individual shutters. To test the compatibility of the different biological systems and their adaptation to the opportunities and constraints of space conditions a profound ground support program has been developed. The procedure and first results of this joint Experiment Verification Tests (EVT) will be presented. The results will be essential for the success of the EXPOSE mission and have been done in parallel with the development and construction of the final hardware design of the facility. The results of the mission will contribute to the understanding of the organic chemistry processes in space, the biological adaptation strategies to extreme conditions, e.g. on early Earth and Mars, and the distribution of life beyond its planet of origin.

  6. Enhancing photogrammetric 3d city models with procedural modeling techniques for urban planning support

    International Nuclear Information System (INIS)

    Schubiger-Banz, S; Arisona, S M; Zhong, C

    2014-01-01

    This paper presents a workflow to increase the level of detail of reality-based 3D urban models. It combines the established workflows from photogrammetry and procedural modeling in order to exploit distinct advantages of both approaches. The combination has advantages over purely automatic acquisition in terms of visual quality, accuracy and model semantics. Compared to manual modeling, procedural techniques can be much more time effective while maintaining the qualitative properties of the modeled environment. In addition, our method includes processes for procedurally adding additional features such as road and rail networks. The resulting models meet the increasing needs in urban environments for planning, inventory, and analysis

  7. Model and Variable Selection Procedures for Semiparametric Time Series Regression

    Directory of Open Access Journals (Sweden)

    Risa Kato

    2009-01-01

    Full Text Available Semiparametric regression models are very useful for time series analysis. They facilitate the detection of features resulting from external interventions. The complexity of semiparametric models poses new challenges for issues of nonparametric and parametric inference and model selection that frequently arise from time series data analysis. In this paper, we propose penalized least squares estimators which can simultaneously select significant variables and estimate unknown parameters. An innovative class of variable selection procedure is proposed to select significant variables and basis functions in a semiparametric model. The asymptotic normality of the resulting estimators is established. Information criteria for model selection are also proposed. We illustrate the effectiveness of the proposed procedures with numerical simulations.

  8. Validation of Short-Term Noise Assessment Procedures: FY16 Summary of Procedures, Progress, and Preliminary Results

    Science.gov (United States)

    summary of the work performed in fiscal year 2016 for the Environment, Safety and Occupational Health Short-Term Noise Assessment Procedure Demonstration...Validation project. This report describes the procedure used to generate the noise models output dataset, and then it compares that dataset to the...algorithm is continuing in FY17. Updates to the noise assessment tools are identified. Throughout this document, procedures used for calculations and analysis are included.

  9. Results of measurement procedure of innovation maturity of business

    Directory of Open Access Journals (Sweden)

    O. A. Kozlova

    2010-09-01

    Full Text Available In this article the basic approaches of innovation maturity of business has been applied. The realization procedure of innovation maturity as an example of organizations of Perm’s region has been call attention. The preliminary potential assessments of perception of plans innovations will give optimize selection innovative strategy for organization and increase the effectiveness of business for microeconomics and region’s level.

  10. A Survey on Procedural Modelling for Virtual Worlds

    NARCIS (Netherlands)

    Smelik, R.M.; Tutenel, T.; Bidarra, R.; Benes, B.

    2014-01-01

    Procedural modelling deals with (semi-)automatic content generation by means of a program or procedure. Among other advantages, its data compression and the potential to generate a large variety of detailed content with reduced human intervention, have made procedural modelling attractive for

  11. Resampling procedures to validate dendro-auxometric regression models

    Directory of Open Access Journals (Sweden)

    2009-03-01

    Full Text Available Regression analysis has a large use in several sectors of forest research. The validation of a dendro-auxometric model is a basic step in the building of the model itself. The more a model resists to attempts of demonstrating its groundlessness, the more its reliability increases. In the last decades many new theories, that quite utilizes the calculation speed of the calculators, have been formulated. Here we show the results obtained by the application of a bootsprap resampling procedure as a validation tool.

  12. Microplastics in Baltic bottom sediments: Quantification procedures and first results.

    Science.gov (United States)

    Zobkov, M; Esiukova, E

    2017-01-30

    Microplastics in the marine environment are known as a global ecological problem but there are still no standardized analysis procedures for their quantification. The first breakthrough in this direction was the NOAA Laboratory Methods for quantifying synthetic particles in water and sediments, but fibers numbers have been found to be underestimated with this approach. We propose modifications for these methods that will allow us to analyze microplastics in bottom sediments, including small fibers. Addition of an internal standard to sediment samples and occasional empty runs are advised for analysis quality control. The microplastics extraction efficiency using the proposed modifications is 92±7%. Distribution of microplastics in bottom sediments of the Russian part of the Baltic Sea is presented. Microplastic particles were found in all of the samples with an average concentration of 34±10 items/kg DW and have the same order of magnitude as neighbor studies reported. Copyright © 2016 Elsevier Ltd. All rights reserved.

  13. A Stepwise Fitting Procedure for automated fitting of Ecopath with Ecosim models

    Science.gov (United States)

    Scott, Erin; Serpetti, Natalia; Steenbeek, Jeroen; Heymans, Johanna Jacomina

    The Stepwise Fitting Procedure automates testing of alternative hypotheses used for fitting Ecopath with Ecosim (EwE) models to observation reference data (Mackinson et al. 2009). The calibration of EwE model predictions to observed data is important to evaluate any model that will be used for ecosystem based management. Thus far, the model fitting procedure in EwE has been carried out manually: a repetitive task involving setting > 1000 specific individual searches to find the statistically 'best fit' model. The novel fitting procedure automates the manual procedure therefore producing accurate results and lets the modeller concentrate on investigating the 'best fit' model for ecological accuracy.

  14. Inference-based procedural modeling of solids

    KAUST Repository

    Biggers, Keith

    2011-11-01

    As virtual environments become larger and more complex, there is an increasing need for more automated construction algorithms to support the development process. We present an approach for modeling solids by combining prior examples with a simple sketch. Our algorithm uses an inference-based approach to incrementally fit patches together in a consistent fashion to define the boundary of an object. This algorithm samples and extracts surface patches from input models, and develops a Petri net structure that describes the relationship between patches along an imposed parameterization. Then, given a new parameterized line or curve, we use the Petri net to logically fit patches together in a manner consistent with the input model. This allows us to easily construct objects of varying sizes and configurations using arbitrary articulation, repetition, and interchanging of parts. The result of our process is a solid model representation of the constructed object that can be integrated into a simulation-based environment. © 2011 Elsevier Ltd. All rights reserved.

  15. Interpreting Results from the Multinomial Logit Model

    DEFF Research Database (Denmark)

    Wulff, Jesper

    2015-01-01

    This article provides guidelines and illustrates practical steps necessary for an analysis of results from the multinomial logit model (MLM). The MLM is a popular model in the strategy literature because it allows researchers to examine strategic choices with multiple outcomes. However, there seem...... to be systematic issues with regard to how researchers interpret their results when using the MLM. In this study, I present a set of guidelines critical to analyzing and interpreting results from the MLM. The procedure involves intuitive graphical representations of predicted probabilities and marginal effects...... suitable for both interpretation and communication of results. The pratical steps are illustrated through an application of the MLM to the choice of foreign market entry mode....

  16. A procedure for Building Product Models

    DEFF Research Database (Denmark)

    Hvam, Lars

    1999-01-01

    activities. A basic assumption is that engineers have to take the responsability for building product models to be used in their domain. To do that they must be able to carry out the modeling task on their own without any need for support from computer science experts. This paper presents a set of simple......The application of product modeling in manufacturing companies raises the important question of how to model product knowledge in a comprehensible and efficient way. An important challenge is to qualify engineers to model and specify IT-systems (product models) to support their specification......, easily adaptable concepts and methods from data modeling (object oriented analysis) and domain modeling (product modeling). The concepts are general and can be used for modeling all types of specifications in the different phases in the product life cycle. The modeling techniques presented have been...

  17. Irrigation customer survey procedures and results: Detailed analysis

    Energy Technology Data Exchange (ETDEWEB)

    Harrer, B.J.; Hattrup, M.P.; Weijo, R.O.

    1987-08-01

    This report presents the results of analyses of data obtained from telephone and in-person survey of irrigators in the Pacific Northwest region. The telephone survey involved approximately 1250 completed responses from irrigators selected from throughout the Northwest. The in-person survey, which is documented in this report, involved approximately 250 completed responses from irrigators within public utility districts that obtain electricity for serving irrigation loads from Bonneville.

  18. A model to determine payments associated with radiology procedures.

    Science.gov (United States)

    Mabotuwana, Thusitha; Hall, Christopher S; Thomas, Shiby; Wald, Christoph

    2017-12-01

    Across the United States, there is a growing number of patients in Accountable Care Organizations and under risk contracts with commercial insurance. This is due to proliferation of new value-based payment models and care delivery reform efforts. In this context, the business model of radiology within a hospital or health system context is shifting from a primary profit-center to a cost-center with a goal of cost savings. Radiology departments need to increasingly understand how the transactional nature of the business relates to financial rewards. The main challenge with current reporting systems is that the information is presented only at an aggregated level, and often not broken down further, for instance, by type of exam. As such, the primary objective of this research is to provide better visibility into payments associated with individual radiology procedures in order to better calibrate expense/capital structure of the imaging enterprise to the actual revenue or value-add to the organization it belongs to. We propose a methodology that can be used to determine technical payments at a procedure level. We use a proportion based model to allocate payments to individual radiology procedures based on total charges (which also includes non-radiology related charges). Using a production dataset containing 424,250 radiology exams we calculated the overall average technical charge for Radiology to be $873.08 per procedure and the corresponding average payment to be $326.43 (range: $48.27 for XR and $2750.11 for PET/CT) resulting in an average payment percentage of 37.39% across all exams. We describe how charges associated with a procedure can be used to approximate technical payments at a more granular level with a focus on Radiology. The methodology is generalizable to approximate payment for other services as well. Understanding payments associated with each procedure can be useful during strategic practice planning. Charge-to-total charge ratio can be used to

  19. Procedural City Layout Generation Based on Urban Land Use Models

    NARCIS (Netherlands)

    Groenewegen, S.A.; Smelik, R.M.; Kraker, J.K. de; Bidarra, R.

    2009-01-01

    Training and simulation applications in virtual worlds require significant amounts of urban environments. Procedural generation is an efficient way to create such models. Existing approaches for procedural modelling of cities aim at facilitating the work of urban planners and artists, but either

  20. Generic Graph Grammar: A Simple Grammar for Generic Procedural Modelling

    DEFF Research Database (Denmark)

    Christiansen, Asger Nyman; Bærentzen, Jakob Andreas

    2012-01-01

    Methods for procedural modelling tend to be designed either for organic objects, which are described well by skeletal structures, or for man-made objects, which are described well by surface primitives. Procedural methods, which allow for modelling of both kinds of objects, are few and usually of...

  1. Procedure to Determine Coefficients for the Sandia Array Performance Model (SAPM)

    Energy Technology Data Exchange (ETDEWEB)

    King, Bruce Hardison; Hansen, Clifford; Riley, Daniel; Robinson, Charles David; Pratt, Larry

    2016-06-01

    The Sandia Array Performance Model (SAPM), a semi-empirical model for predicting PV system power, has been in use for more than a decade. While several studies have presented comparisons of measurements and analysis results among laboratories, detailed procedures for determining model coefficients have not yet been published. Independent test laboratories must develop in-house procedures to determine SAPM coefficients, which contributes to uncertainty in the resulting models. Here we present a standard procedure for calibrating the SAPM using outdoor electrical and meteorological measurements. Analysis procedures are illustrated with data measured outdoors for a 36-cell silicon photovoltaic module.

  2. Procedures for Geometric Data Reduction in Solid Log Modelling

    Science.gov (United States)

    Luis G. Occeña; Wenzhen Chen; Daniel L. Schmoldt

    1995-01-01

    One of the difficulties in solid log modelling is working with huge data sets, such as those that come from computed axial tomographic imaging. Algorithmic procedures are described in this paper that have successfully reduced data without sacrificing modelling integrity.

  3. A Numerical Comparison of Three Procedures Used in Failure Model Discrimination

    Directory of Open Access Journals (Sweden)

    Samir Kamel Ashour

    2014-05-01

    Full Text Available Three different selection procedures namely RML, S and F-procedure are reviewed with application to exponential, Weibull, Pareto, and Finite range models. Some inacurate results were discovered in the article of Pandy et al. (1991, it will be illustrated and modified. A simulation study is developed to numerically compare between the three procedures by obtaining the probability of correct selection

  4. Power mos devices: structures and modelling procedures

    Energy Technology Data Exchange (ETDEWEB)

    Rossel, P.; Charitat, G.; Tranduc, H.; Morancho, F.; Moncoqut

    1997-05-01

    In this survey, the historical evolution of power MOS transistor structures is presented and currently used devices are described. General considerations on current and voltage capabilities are discussed and configurations of popular structures are given. A synthesis of different modelling approaches proposed last three years is then presented, including analytical solutions, for basic electrical parameters such as threshold voltage, on-resistance, saturation and quasi-saturation effects, temperature influence and voltage handling capability. The numerical solutions of basic semiconductor devices is then briefly reviewed along with some typical problems which can be solved this way. A compact circuit modelling method is finally explained with emphasis on dynamic behavior modelling

  5. Procedural meta-models for architectural design praxis

    Directory of Open Access Journals (Sweden)

    Gian Luca Brunetti

    2013-05-01

    Full Text Available This article discusses a procedure for the exploration of options in preliminary design. The procedure is based on the application of morphing procedures, which are typical of animation software, to building parametric analyses. The procedure is based on partially overlapping sequences of evaluations targeted on dynamic ad-hoc test-models and is aimed at the creation of data fields for the representation of the performance consequences of competing design sceneries. This representation is necessarily multidimensional and is based on parallel coordinates plots. The implementation of a specific test procedure of the kind described above is also discussed. The procedure has been supported by the use of contemporary analytical and representational systems and tools; namely, ESP-r, Radiance, Ggobi, and an extensible tool for the dynamic morphing of models through user-specified criteria, named OPTS, by the author.

  6. Application of a procedure oriented crew model to modelling nuclear plant operation

    International Nuclear Information System (INIS)

    Baron, S.

    1986-01-01

    PROCRU (PROCEDURE-ORIENTED CREW MODEL) is a model developed to analyze flight crew procedures in a commercial ILS approach-to-landing. The model builds on earlier, validated control-theoretic models for human estimation and control behavior, but incorporates features appropriate to analyzing supervisory control in multi-task environments. In this paper, the basic ideas underlying the PROCRU model, and the generalization of these ideas to provide a supervisory control model of wider applicability are discussed. The potential application of this supervisory control model to nuclear power plant operations is considered. The range of problems that can be addressed, the kinds of data that will be needed and the nature of the results that might be expected from such an application are indicated

  7. Procedures and results of the measurements on large area photomultipliers for the NEMO project

    Science.gov (United States)

    Aiello, S.; Leonora, E.; Aloisio, A.; Ameli, F.; Amore, I.; Anghinolfi, M.; Anzalone, A.; Barbarino, G.; Barbarito, E.; Battaglieri, M.; Bazzotti, M.; Bellotti, R.; Bersani, A.; Beverini, N.; Biagi, S.; Bonori, M.; Bouhdaef, B.; Cacopardo, G.; Calı, C.; Capone, A.; Caponetto, L.; Carminati, G.; Cassano, B.; Ceres, A.; Chiarusi, T.; Circella, M.; Cocimano, R.; Coniglione, R.; Cordelli, M.; Costa, M.; D'Amico, A.; DeBonis, G.; DeRosa, G.; DeRuvo, G.; DeVita, R.; Distefano, C.; Flaminio, V.; Fratini, K.; Gabrielli, A.; Galeotti, S.; Gandolfi, E.; Giacomelli, G.; Giorgi, F.; Giovanetti, G.; Grimaldi, A.; Grmek, A.; Habel, R.; Imbesi, M.; Lonardo, A.; LoPresti, D.; Lucarelli, F.; Margiotta, A.; Marinelli, A.; Martini, A.; Masullo, R.; Maugeri, F.; Migneco, E.; Minutoli, S.; Mongelli, M.; Morganti, M.; Musico, P.; Musumeci, M.; Orlando, A.; Osipenko, M.; Papaleo, R.; Pappalardo, V.; Piattelli, P.; Piombo, D.; Raffaelli, F.; Raia, G.; Randazzo, N.; Reito, S.; Ricco, G.; Riccobene, G.; Ripani, M.; Rovelli, A.; Ruppi, M.; Russo, G. V.; Russo, S.; Sapienza, P.; Sedita, M.; Shirokov, E.; Simeone, F.; Sciliberto, D.; Sipala, V.; Sollima, C.; Spurio, M.; Stefani, F.; Taiuti, M.; Terreni, G.; Trasatti, L.; Urso, S.; Vecchi, M.; Vicini, P.; Wischnewski, R.

    2010-03-01

    The selection of the photomultiplier plays a crucial role in the R&D activity related to a large-scale underwater neutrino telescope. This paper illustrates the main procedures and facilities used to characterize the performances of 72 large area photomultipliers, Hamamatsu model R7081 sel. The voltage to achieve a gain of 5×10 7, dark count rate and single photoelectron time and charge properties of the overall response were measured with a properly attenuated 410 nm pulsed laser. A dedicated study of the spurious pulses was also performed. The results prove that the photomultipliers comply with the general requirements imposed by the project.

  8. A skin abscess model for teaching incision and drainage procedures.

    Science.gov (United States)

    Fitch, Michael T; Manthey, David E; McGinnis, Henderson D; Nicks, Bret A; Pariyadath, Manoj

    2008-07-03

    Skin and soft tissue infections are increasingly prevalent clinical problems, and it is important for health care practitioners to be well trained in how to treat skin abscesses. A realistic model of abscess incision and drainage will allow trainees to learn and practice this basic physician procedure. We developed a realistic model of skin abscess formation to demonstrate the technique of incision and drainage for educational purposes. The creation of this model is described in detail in this report. This model has been successfully used to develop and disseminate a multimedia video production for teaching this medical procedure. Clinical faculty and resident physicians find this model to be a realistic method for demonstrating abscess incision and drainage. This manuscript provides a detailed description of our model of abscess incision and drainage for medical education. Clinical educators can incorporate this model into skills labs or demonstrations for teaching this basic procedure.

  9. Validation of the PESTLA model: Definitions, objectives and procedure

    NARCIS (Netherlands)

    Boekhold AE; van den Bosch H; Boesten JJTI; Leistra M; Swartjes FA; van der Linden AMA

    1993-01-01

    The simulation model PESTLA was developed to produce estimates of accumulation and leaching of pesticides in soil to facilitate classification of pesticides in the Dutch registration procedure. Before PESTLA can be used for quantitative assessment of expected pesticide concentrations in

  10. Design Transformations for Rule-based Procedural Modeling

    KAUST Repository

    Lienhard, Stefan

    2017-05-24

    We introduce design transformations for rule-based procedural models, e.g., for buildings and plants. Given two or more procedural designs, each specified by a grammar, a design transformation combines elements of the existing designs to generate new designs. We introduce two technical components to enable design transformations. First, we extend the concept of discrete rule switching to rule merging, leading to a very large shape space for combining procedural models. Second, we propose an algorithm to jointly derive two or more grammars, called grammar co-derivation. We demonstrate two applications of our work: we show that our framework leads to a larger variety of models than previous work, and we show fine-grained transformation sequences between two procedural models.

  11. VEMAP 1: Selected Model Results

    Data.gov (United States)

    National Aeronautics and Space Administration — The Vegetation/Ecosystem Modeling and Analysis Project (VEMAP) was a multi-institutional, international effort addressing the response of biogeography and...

  12. SYNTHESIS OF INFORMATION MODEL FOR ALTERNATIVE FUNCTIONAL DIAGNOSTICS PROCEDURE

    OpenAIRE

    P. F. Shchapov; R. P. Miguschenko

    2014-01-01

    Probabilistic approaches in information theory and information theory of measurement, allowing to calculate and analyze the amount expected to models measuring conversions and encoding tasks random measurement signals were considered. A probabilistic model of diagnostic information model transformation and diagnostic procedures was developed. Conditions for obtaining the maximum amount of diagnostic information were found out.

  13. VEMAP 1: Selected Model Results

    Data.gov (United States)

    National Aeronautics and Space Administration — ABSTRACT: The Vegetation/Ecosystem Modeling and Analysis Project (VEMAP) was a multi-institutional, international effort addressing the response of biogeography and...

  14. Using an Instructional Design Model to Teach Medical Procedures.

    Science.gov (United States)

    Cheung, Lawrence

    Educators are often tasked with developing courses and curricula that teach learners how to perform medical procedures. This instruction must provide an optimal, uniform learning experience for all learners. If not well designed, this instruction risks being unstructured, informal, variable amongst learners, or incomplete. This article shows how an instructional design model can help craft courses and curricula to optimize instruction in performing medical procedures. Educators can use this as a guide to developing their own course instruction.

  15. Procedures for parameter estimates of computational models for localized failure

    NARCIS (Netherlands)

    Iacono, C.

    2007-01-01

    In the last years, many computational models have been developed for tensile fracture in concrete. However, their reliability is related to the correct estimate of the model parameters, not all directly measurable during laboratory tests. Hence, the development of inverse procedures is needed, that

  16. 40 CFR 761.357 - Reporting the results of the procedure used to simulate leachate generation.

    Science.gov (United States)

    2010-07-01

    ... used to simulate leachate generation. 761.357 Section 761.357 Protection of Environment ENVIRONMENTAL... of the procedure used to simulate leachate generation. Report the results of the procedure used to simulate leachate generation as micrograms PCBs per liter of extract from a 100 gram sample of dry bulk...

  17. GENERATING ALTERNATIVE PROPOSALS FOR THE LOUVRE USING PROCEDURAL MODELING

    Directory of Open Access Journals (Sweden)

    E. Calogero

    2012-09-01

    Full Text Available This paper presents the process of reconstructing two facade designs for the East wing of the Louvre using procedural modeling. The first proposal reconstructed is Louis Le Vau's 1662 scheme and the second is the 1668 design of the "petit conseil" that still stands today. The initial results presented show how such reconstructions may aid general and expert understanding of the two designs. It is claimed that by formalizing the facade description into a shape grammar in CityEngine, a systematized approach to a stylistic analysis is possible. It is also asserted that such an analysis is still best understood in the historical context of what is known about the contemporary design intentions of the building creators and commissioners.

  18. Generating Alternative Proposals for the Louvre Using Procedural Modeling

    Science.gov (United States)

    Calogero, E.; Arnold, D.

    2011-09-01

    This paper presents the process of reconstructing two facade designs for the East wing of the Louvre using procedural modeling. The first proposal reconstructed is Louis Le Vau's 1662 scheme and the second is the 1668 design of the "petit conseil" that still stands today. The initial results presented show how such reconstructions may aid general and expert understanding of the two designs. It is claimed that by formalizing the facade description into a shape grammar in CityEngine, a systematized approach to a stylistic analysis is possible. It is also asserted that such an analysis is still best understood in the historical context of what is known about the contemporary design intentions of the building creators and commissioners.

  19. A Stepwise Fitting Procedure for automated fitting of Ecopath with Ecosim models

    Directory of Open Access Journals (Sweden)

    Erin Scott

    2016-01-01

    Full Text Available The Stepwise Fitting Procedure automates testing of alternative hypotheses used for fitting Ecopath with Ecosim (EwE models to observation reference data (Mackinson et al. 2009. The calibration of EwE model predictions to observed data is important to evaluate any model that will be used for ecosystem based management. Thus far, the model fitting procedure in EwE has been carried out manually: a repetitive task involving setting >1000 specific individual searches to find the statistically ‘best fit’ model. The novel fitting procedure automates the manual procedure therefore producing accurate results and lets the modeller concentrate on investigating the ‘best fit’ model for ecological accuracy.

  20. Model checking as an aid to procedure design

    International Nuclear Information System (INIS)

    Zhang, Wenhu

    2001-01-01

    The OECD Halden Reactor Project has been actively working on computer assisted operating procedures for many years. The objective of the research has been to provide computerised assistance for procedure design, verification and validation, implementation and maintenance. For the verification purpose, the application of formal methods has been considered in several reports. The recent formal verification activity conducted at the Halden Project is based on using model checking to the verification of procedures. This report presents verification approaches based on different model checking techniques and tools for the formalization and verification of operating procedures. Possible problems and relative merits of the different approaches are discussed. A case study of one of the approaches is presented to show the practical application of formal verification. Application of formal verification in the traditional procedure design process can reduce the human resources involved in reviews and simulations, and hence reduce the cost of verification and validation. A discussion of the integration of the formal verification with the traditional procedure design process is given at the end of this report. (Author)

  1. A procedure for determining parameters of a simplified ligament model.

    Science.gov (United States)

    Barrett, Jeff M; Callaghan, Jack P

    2018-01-03

    A previous mathematical model of ligament force-generation treated their behavior as a population of collagen fibres arranged in parallel. When damage was ignored in this model, an expression for ligament force in terms of the deflection, x, effective stiffness, k, mean collagen slack length, μ, and the standard deviation of slack lengths, σ, was obtained. We present a simple three-step method for determining the three model parameters (k, μ, and σ) from force-deflection data: (1) determine the equation of the line in the linear region of this curve, its slope is k and its x -intercept is -μ; (2) interpolate the force-deflection data when x is -μ to obtain F 0 ; (3) calculate σ with the equation σ=2πF 0 /k. Results from this method were in good agreement to those obtained from a least-squares procedure on experimental data - all falling within 6%. Therefore, parameters obtained using the proposed method provide a systematic way of reporting ligament parameters, or for obtaining an initial guess for nonlinear least-squares. Copyright © 2017 Elsevier Ltd. All rights reserved.

  2. Procedural Skills Education – Colonoscopy as a Model

    Directory of Open Access Journals (Sweden)

    Maitreyi Raman

    2008-01-01

    Full Text Available Traditionally, surgical and procedural apprenticeship has been an assumed activity of students, without a formal educational context. With increasing barriers to patient and operating room access such as shorter work week hours for residents, and operating room and endoscopy time at a premium, alternate strategies to maximizing procedural skill development are being considered. Recently, the traditional surgical apprenticeship model has been challenged, with greater emphasis on the need for surgical and procedural skills training to be more transparent and for alternatives to patient-based training to be considered. Colonoscopy performance is a complex psychomotor skill requiring practioners to integrate multiple sensory inputs, and involves higher cortical centres for optimal performance. Colonoscopy skills involve mastery in the cognitive, technical and process domains. In the present review, we propose a model for teaching colonoscopy to the novice trainee based on educational theory.

  3. Communication and Procedural Models of the E-Commerce Systems

    Directory of Open Access Journals (Sweden)

    Petr SUCHÁNEK

    2009-06-01

    Full Text Available E-commerce systems became a standard interface between sellers (or suppliers and customers. One of basic condition of an e-commerce system to be efficient is correct definitions and describes of the all internal and external processes. All is targeted the customers´ needs and requirements. The optimal and most exact way how to obtain and find optimal solution of e-commerce system and its processes structure in companies is the modeling and simulation. In this article author shows basic model of communication between customers and sellers in connection with the customer feedback and procedural models of e-commerce systems in terms of e-shops. Procedural model was made with the aid of definition of SOA.

  4. A simple but accurate procedure for solving the five-parameter model

    International Nuclear Information System (INIS)

    Mares, Oana; Paulescu, Marius; Badescu, Viorel

    2015-01-01

    Highlights: • A new procedure for extracting the parameters of the one-diode model is proposed. • Only the basic information listed in the datasheet of PV modules are required. • Results demonstrate a simple, robust and accurate procedure. - Abstract: The current–voltage characteristic of a photovoltaic module is typically evaluated by using a model based on the solar cell equivalent circuit. The complexity of the procedure applied for extracting the model parameters depends on data available in manufacture’s datasheet. Since the datasheet is not detailed enough, simplified models have to be used in many cases. This paper proposes a new procedure for extracting the parameters of the one-diode model in standard test conditions, using only the basic data listed by all manufactures in datasheet (short circuit current, open circuit voltage and maximum power point). The procedure is validated by using manufacturers’ data for six commercially crystalline silicon photovoltaic modules. Comparing the computed and measured current–voltage characteristics the determination coefficient is in the range 0.976–0.998. Thus, the proposed procedure represents a feasible tool for solving the five-parameter model applied to crystalline silicon photovoltaic modules. The procedure is described in detail, to guide potential users to derive similar models for other types of photovoltaic modules.

  5. A verification procedure for MSC/NASTRAN Finite Element Models

    Science.gov (United States)

    Stockwell, Alan E.

    1995-01-01

    Finite Element Models (FEM's) are used in the design and analysis of aircraft to mathematically describe the airframe structure for such diverse tasks as flutter analysis and actively controlled landing gear design. FEM's are used to model the entire airplane as well as airframe components. The purpose of this document is to describe recommended methods for verifying the quality of the FEM's and to specify a step-by-step procedure for implementing the methods.

  6. Sensitivity of Hydrologic Response to Climate Model Debiasing Procedures

    Science.gov (United States)

    Channell, K.; Gronewold, A.; Rood, R. B.; Xiao, C.; Lofgren, B. M.; Hunter, T.

    2017-12-01

    Climate change is already having a profound impact on the global hydrologic cycle. In the Laurentian Great Lakes, changes in long-term evaporation and precipitation can lead to rapid water level fluctuations in the lakes, as evidenced by unprecedented change in water levels seen in the last two decades. These fluctuations often have an adverse impact on the region's human, environmental, and economic well-being, making accurate long-term water level projections invaluable to regional water resources management planning. Here we use hydrological components from a downscaled climate model (GFDL-CM3/WRF), to obtain future water supplies for the Great Lakes. We then apply a suite of bias correction procedures before propagating these water supplies through a routing model to produce lake water levels. Results using conventional bias correction methods suggest that water levels will decline by several feet in the coming century. However, methods that reflect the seasonal water cycle and explicitly debias individual hydrological components (overlake precipitation, overlake evaporation, runoff) imply that future water levels may be closer to their historical average. This discrepancy between debiased results indicates that water level forecasts are highly influenced by the bias correction method, a source of sensitivity that is commonly overlooked. Debiasing, however, does not remedy misrepresentation of the underlying physical processes in the climate model that produce these biases and contribute uncertainty to the hydrological projections. This uncertainty coupled with the differences in water level forecasts from varying bias correction methods are important for water management and long term planning in the Great Lakes region.

  7. Results of Combined Intraventricular Neuroendoscopic Procedures in 130 Cases with Special Focus on Fornix Contusions.

    Science.gov (United States)

    Oertel, Joachim; Linsler, Stefan; Emmerich, Caroline; Keiner, Dörthe; Gaab, Michael; Schroeder, Henry; Senger, Sebastian

    2017-12-01

    Increasing experience with intraventricular neuroendoscopic procedures shows good results in the combination of endoscopic third ventriculostomy (ETV) and tumor biopsy. Other possible combinations are mainly presented in subgroups in the literature. Here, we present our experience with combined intraventricular procedures within 1 setting over the last 2 decades. This study retrospectively analyzes data from neuroendoscopic intraventricular procedures between 1993 and 2015 in 3 different departments of neurosurgery. Inclusion criteria were a combination of at least 2 intraventricular endoscopic procedures (e.g. third ventriculostomy, cyst fenestration, tumor surgery or aqueductoplasty) within 1 setting. One-hundred and thirty cases with more than 300 procedures fulfilled the inclusion criteria. The most frequent combinations were ETV and tumor biopsy (n = 36), ETV and aqueductoplasty/stenting (n = 30), and ETV and cyst fenestration (n = 18). The complication rate was 16.9% with an overall morbidity of 1.6% and mortality of 0.8%. Fornix contusion was one of the most frequent intraoperative complications (16.4%). Shunt independency was achieved in 82.9% of cases with hydrocephalic symptoms. A combination of different intraventricular endoscopic procedures is safe and reliable, bearing similar risks of morbidities and mortality to single neuroendoscopic procedures. This study is one of the largest series in the literature and has similar low complication rates to others. Fornix contusion is the most frequent intraoperative complication in these patients. However, obvious clinical correlation is rare. Copyright © 2017. Published by Elsevier Inc.

  8. An innovative model for teaching and learning clinical procedures.

    Science.gov (United States)

    Kneebone, Roger; Kidd, Jane; Nestel, Debra; Asvall, Suzanne; Paraskeva, Paraskevas; Darzi, Ara

    2002-07-01

    Performing a clinical procedure requires the integration of technical clinical skills with effective communication skills. However, these skills are often taught separately. To explore the feasibility and benefits of a new conceptual model for integrated skills teaching. : Design A qualitative observation and interview-based study of undergraduate medical students. Medical students performed technical and communication skills in realistic clinical scenarios (urinary catherization and wound closure), using latex models connected to simulated patients (SPs). Procedures were observed, videorecorded and assessed by tutors from an adjoining room. Students received immediate feedback from tutors and SPs, before engaging in a process of individual feedback through private review of their videotapes. Group interviews explored the response of students, SPs and tutors. Data were analysed using standard qualitative techniques. Fifty-one undergraduate students were recruited from the Faculty of Medicine, Imperial College, London. The scenarios provided a realistic simulation of two common clinical situations and proved feasible in terms of time, facilities and resources within this institution. Students found the opportunity to integrate communication and technical skills valuable, challenging and an appropriate learning experience. Immediate feedback was especially highly valued. Some students found difficulty integrating technical and communications skills, but benefited from conducting two procedures in the same session. The integrated model was feasible and was perceived to be valuable. Benefits include the opportunity to integrate, within a safe environment, skills which are often taught separately. Promoting reflective practice may enable the successful transfer of these integrated skills to other procedures.

  9. Effect of adipose tissue processing procedures in culture result: a study preliminary

    Directory of Open Access Journals (Sweden)

    Jeanne A. Pawitan

    2011-02-01

    Full Text Available Background: There are various methods of processing adipose tissue before culture, depending on the adipose tissue samples. The aim of this study is to compare several modifications of culturing and sub-culturing procedures of adipose tissue to fit the condition in our laboratory.Method: This is a descriptive study that was done in the Immunology and Endocrinology Integrated Laboratory, University of Indonesia, from  October 2009 to April 2010. Three adipose tissue processing procedures, various amount of seeding and two subculture methods were compared in term of cell yield and time needed. In the first procedure, collagenase-1 digestion was done in 30minutes, cell seeding were 24,000 and 36,000 per flask; in the second procedure, collagenase-1 digestion was done in 60minutes, cell seeding were 24,000, 48,000, and 72,000 per flask; and in the third procedure, the adipose tissue remnants from the first  procedure were again digested for another 45 minutes, cell seeding were 74,000, and 148,000 per flask. Difference in subculture methods were the presence or absence of washing step.Result: Procedure 1 yielded the lowest amount of cell, and after culture, the cells grew very slow, and was contaminated before harvest of primary culture. Procedure-2 and -3 succeeded to yield primary cultures. Some of the cultures were contaminated, so that further subculture was not  applicable, and only one tissue processing procedure (procedure 2: 60 minute collagenase-1 digestion, without lysis buffer, cell seeding 48,000 and 72,000 could complete the three subcultures. Though some of the procedures could not be completed, final result could be concluded.Conclusion: In this preliminary study, 60 minute colagenase-1 digestion with intermittent shaking every 5 minutes and cell seeding around 50,000 or more, followed by subculture method without washing step gave the best result. (Med J Indones 2011; 20:15-9Keywords: collagenase-1, primary culture, subculture

  10. Computer–Based Procedures for Nuclear Power Plant Field Workers: Preliminary Results from Two Evaluation Studies

    Energy Technology Data Exchange (ETDEWEB)

    Katya L Le Blanc; Johanna H Oxstrand

    2013-10-01

    The Idaho National Laboratory and participants from the U.S. nuclear industry are collaborating on a research effort aimed to augment the existing guidance on computer-based procedure (CBP) design with specific guidance on how to design CBP user interfaces such that they support procedure execution in ways that exceed the capabilities of paper-based procedures (PBPs) without introducing new errors. Researchers are employing an iterative process where the human factors issues and interface design principles related to CBP usage are systematically addressed and evaluated in realistic settings. This paper describes the process of developing a CBP prototype and the two studies conducted to evaluate the prototype. The results indicate that CBPs may improve performance by reducing errors, but may increase the time it takes to complete procedural tasks.

  11. Evaluating procedural modelling for 3D models of informal settlements in urban design activities

    Directory of Open Access Journals (Sweden)

    Victoria Rautenbach

    2015-11-01

    Full Text Available Three-dimensional (3D modelling and visualisation is one of the fastest growing application fields in geographic information science. 3D city models are being researched extensively for a variety of purposes and in various domains, including urban design, disaster management, education and computer gaming. These models typically depict urban business districts (downtown or suburban residential areas. Despite informal settlements being a prevailing feature of many cities in developing countries, 3D models of informal settlements are virtually non-existent. 3D models of informal settlements could be useful in various ways, e.g. to gather information about the current environment in the informal settlements, to design upgrades, to communicate these and to educate inhabitants about environmental challenges. In this article, we described the development of a 3D model of the Slovo Park informal settlement in the City of Johannesburg Metropolitan Municipality, South Africa. Instead of using time-consuming traditional manual methods, we followed the procedural modelling technique. Visualisation characteristics of 3D models of informal settlements were described and the importance of each characteristic in urban design activities for informal settlement upgrades was assessed. Next, the visualisation characteristics of the Slovo Park model were evaluated. The results of the evaluation showed that the 3D model produced by the procedural modelling technique is suitable for urban design activities in informal settlements. The visualisation characteristics and their assessment are also useful as guidelines for developing 3D models of informal settlements. In future, we plan to empirically test the use of such 3D models in urban design projects in informal settlements.

  12. A baseline-free procedure for transformation models under interval censorship.

    Science.gov (United States)

    Gu, Ming Gao; Sun, Liuquan; Zuo, Guoxin

    2005-12-01

    An important property of Cox regression model is that the estimation of regression parameters using the partial likelihood procedure does not depend on its baseline survival function. We call such a procedure baseline-free. Using marginal likelihood, we show that an baseline-free procedure can be derived for a class of general transformation models under interval censoring framework. The baseline-free procedure results a simplified and stable computation algorithm for some complicated and important semiparametric models, such as frailty models and heteroscedastic hazard/rank regression models, where the estimation procedures so far available involve estimation of the infinite dimensional baseline function. A detailed computational algorithm using Markov Chain Monte Carlo stochastic approximation is presented. The proposed procedure is demonstrated through extensive simulation studies, showing the validity of asymptotic consistency and normality. We also illustrate the procedure with a real data set from a study of breast cancer. A heuristic argument showing that the score function is a mean zero martingale is provided.

  13. Spiral model of procedural cycle of educational process management

    OpenAIRE

    Bezrukov Valery I.; Lukashina Elena V.

    2016-01-01

    The article analyzes the nature and characteristics of the spiral model Procedure educational systems management cycle. The authors identify patterns between the development of information and communication technologies and the transformation of the education management process, give the characteristics of the concept of “information literacy” and “Media Education”. Consider the design function, determine its potential in changing the traditional educational paradigm to the new - information....

  14. Patient dose assessment in various Interventional radiology and cardiology procedures in Algeria (IAEA regional project results)

    International Nuclear Information System (INIS)

    Khelassi-Toutaoui, Nadia; Merad, Ahmed; Toutaoui, A.E.K.; Bairi, Souad

    2008-01-01

    Full text: Purpose: To evaluate patient doses in Interventional Radiology (IR) and Cardiology (IC) procedures in Algeria, within the framework of an International Atomic Energy Agency (IAEA) regional project on radiation protection of patients and medical exposure control (RAF 9033). Materials and Methods: Three public hospitals (CHU Bab el Oued, CHU Parnet and CHU Mustapha) and one specialised Cardiology Service (Clinique Maouche) were chosen for the study. For Maximum Skin Dose (MSD) evaluation, gafchromic films XR type R were used, placed on patient's back before the procedure. The Dose Area Product (DAP) and MSD were measured in 57 IR and IC procedures, either diagnostic or therapeutic. Results: The results revealed large variations in MSD (0.06-3.3 Gy) and DAP (5.5-332 mGycm 2 ). Mean MSD was 0.227 Gy in cerebral angiography, 0.202 Gy in coronary angiography, 1.162 Gy in Percutaneus Transluminal Coronary Angioplasty (PTCA) and 0.128 in abdominal angiography. The correlation of DAP and MSD was significant (r = 0.7). The correlation was DAP and fluoroscopy time was also significant (r = 0.8). Conclusion: The highest MSD values were found in PTCA which is a therapeutic procedure. Two PTCAs out of the 57 procedures measured in total had MSD over the threshold of 2 Gy for deterministic effects (MSD 1 = 3.0 Gy and MSD 2 3.3 Gy). The large variations in MSD reveal the need to continuously monitor patient doses in IR and IC procedures with special emphasis in PTCA procedure. (author)

  15. Drawing-Based Procedural Modeling of Chinese Architectures.

    Science.gov (United States)

    Fei Hou; Yue Qi; Hong Qin

    2012-01-01

    This paper presents a novel modeling framework to build 3D models of Chinese architectures from elevation drawing. Our algorithm integrates the capability of automatic drawing recognition with powerful procedural modeling to extract production rules from elevation drawing. First, different from the previous symbol-based floor plan recognition, based on the novel concept of repetitive pattern trees, small horizontal repetitive regions of the elevation drawing are clustered in a bottom-up manner to form architectural components with maximum repetition, which collectively serve as building blocks for 3D model generation. Second, to discover the global architectural structure and its components' interdependencies, the components are structured into a shape tree in a top-down subdivision manner and recognized hierarchically at each level of the shape tree based on Markov Random Fields (MRFs). Third, shape grammar rules can be derived to construct 3D semantic model and its possible variations with the help of a 3D component repository. The salient contribution lies in the novel integration of procedural modeling with elevation drawing, with a unique application to Chinese architectures.

  16. Recreation of architectural structures using procedural modeling based on volumes

    Directory of Open Access Journals (Sweden)

    Santiago Barroso Juan

    2013-11-01

    Full Text Available While the procedural modeling of buildings and other architectural structures has evolved very significantly in recent years, there is noticeable absence of high-level tools that allow a designer, an artist or an historian, creating important buildings or architectonic structures in a particular city. In this paper we present a tool for creating buildings in a simple and clear, following rules that use the language and methodology of creating their own buildings, and hiding the user the algorithmic details of the creation of the model.

  17. Procedural Modeling for Rapid-Prototyping of Multiple Building Phases

    Science.gov (United States)

    Saldana, M.; Johanson, C.

    2013-02-01

    RomeLab is a multidisciplinary working group at UCLA that uses the city of Rome as a laboratory for the exploration of research approaches and dissemination practices centered on the intersection of space and time in antiquity. In this paper we present a multiplatform workflow for the rapid-prototyping of historical cityscapes through the use of geographic information systems, procedural modeling, and interactive game development. Our workflow begins by aggregating archaeological data in a GIS database. Next, 3D building models are generated from the ArcMap shapefiles in Esri CityEngine using procedural modeling techniques. A GIS-based terrain model is also adjusted in CityEngine to fit the building elevations. Finally, the terrain and city models are combined in Unity, a game engine which we used to produce web-based interactive environments which are linked to the GIS data using keyhole markup language (KML). The goal of our workflow is to demonstrate that knowledge generated within a first-person virtual world experience can inform the evaluation of data derived from textual and archaeological sources, and vice versa.

  18. Early and medium term results of the sleeve valve-sparing procedure for aortic root ectasia.

    Science.gov (United States)

    Gamba, Amando; Tasca, Giordano; Giannico, Floriana; Lobiati, Elisabetta; Skouse, Douglas; Galanti, Andrea; Martino, Antonello Stefano; Triggiani, Michele

    2015-04-01

    The aim of this retrospective study was to evaluate our experience of using a simplified aortic valve sleeve procedure to treat aortic root ectasia and aneurysms with or without aortic regurgitation. In experienced hands, 2 aortic valve-sparing procedures, ie, Yacoub and David, have yielded excellent long-term results in the treatment of aortic root aneurysms, with or without aortic regurgitation. However, these techniques are demanding and not widely used. Recently, a new and simplified valve-sparing technique, named "sleeve procedure," has been proposed, and has yielded encouraging early results. Ninety consecutive patients with aortic root aneurysms underwent sleeve procedures from October 2006 to October 2012. Follow-up data (clinical 100% complete and echocardiographic 93% complete) were acquired from our outpatient clinic or from the referring cardiologist. The mean age of the patients was 61.5 ± 12.5 years, 79% were male, 16 (18%) had a bicuspid valve, 3 had Marfan syndrome, and 2 had aortic dissection. Over a mean clinical follow-up of 34 ± 19 months, 2 patients died from noncardiac causes and 1 was reoperated on for the recurrence of aortic regurgitation. On follow-up echocardiography after a mean of 18 ± 9 months, aortic regurgitation was absent/negligible, mild or moderate in 62%, 37%, and 1% of patients, respectively, and the diameters of the annulus, Valsalva sinuses, and sinotubular junction were 27.3 + 2.2, 37.0 + 3.4, and 30.6 + 3.1 mm, respectively. Our encouraging early and medium term results suggest that the sleeve procedure is a safe and effective aortic valve-sparing technique for the treatment of aortic root ectasia and aneurysm. However, longer follow-up is needed in order to draw definitive conclusions. Copyright © 2015 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

  19. Stepwise calibration procedure for regional coupled hydrological-hydrogeological models

    Science.gov (United States)

    Labarthe, Baptiste; Abasq, Lena; de Fouquet, Chantal; Flipo, Nicolas

    2014-05-01

    Stream-aquifer interaction is a complex process depending on regional and local processes. Indeed, the groundwater component of hydrosystem and large scale heterogeneities control the regional flows towards the alluvial plains and the rivers. In second instance, the local distribution of the stream bed permeabilities controls the dynamics of stream-aquifer water fluxes within the alluvial plain, and therefore the near-river piezometric head distribution. In order to better understand the water circulation and pollutant transport in watersheds, the integration of these multi-dimensional processes in modelling platform has to be performed. Thus, the nested interfaces concept in continental hydrosystem modelling (where regional fluxes, simulated by large scale models, are imposed at local stream-aquifer interfaces) has been presented in Flipo et al (2014). This concept has been implemented in EauDyssée modelling platform for a large alluvial plain model (900km2) part of a 11000km2 multi-layer aquifer system, located in the Seine basin (France). The hydrosystem modelling platform is composed of four spatially distributed modules (Surface, Sub-surface, River and Groundwater), corresponding to four components of the terrestrial water cycle. Considering the large number of parameters to be inferred simultaneously, the calibration process of coupled models is highly computationally demanding and therefore hardly applicable to a real case study of 10000km2. In order to improve the efficiency of the calibration process, a stepwise calibration procedure is proposed. The stepwise methodology involves determining optimal parameters of all components of the coupled model, to provide a near optimum prior information for the global calibration. It starts with the surface component parameters calibration. The surface parameters are optimised based on the comparison between simulated and observed discharges (or filtered discharges) at various locations. Once the surface parameters

  20. Patient-oriented presentation of results of radiological procedures using DICOM-compliant DVD media

    Science.gov (United States)

    Ratib, Osman M.; Aberle, Denise R.; Goldin, Jonathan G.; Lu, David S.; Dahlbom, Magdalena; McGill, D. Ric; McCoy, J. Michael

    2003-05-01

    Some institutions have adopted digital media such as CD ROMs to provide patients and referring physicians with results of radiological procedures. These systems require a computer to review the images and lack the supporting explanations and guidance for patients to properly understand the results. We developed a hybrid DVD encoding format that combines DICOM-compliant image storage format with video streams viewable on any consumer DVD players. The addition of the video material allows radiologists to provide explanations, disclaimers and guidance to the patients regarding the results of the study. The diagnostic report is also included on the DVD as a PDF file and as a set of video frames that can be viewed on a DVD player. The native high-resolution images are also included in DICOM format on the DVD and can be accessed by any workstation equipped with a DICOM viewer. The DVD that can be reviewed on any consumer DVD player overcomes the limitation of CD ROMS that require the use of a personal computer. The results of the radiological procedures become more accessible patients that could be reluctant or unable to use a computer. Also, live video clips add a more personalized note and allow radiologists to convey important messages to the patients. This is particularly useful for self-referred screening procedures where results should always be accompanied with education material and explanations of the findings.

  1. Long-term results of the Ross procedure in a population-based follow-up.

    Science.gov (United States)

    Kallio, Merja; Pihkala, Jaana; Sairanen, Heikki; Mattila, Ilkka

    2015-05-01

    centre, the Ross procedure has provided good long-term results in this challenging group of paediatric patients. © The Author 2015. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.

  2. a Procedural Solution to Model Roman Masonry Structures

    Science.gov (United States)

    Cappellini, V.; Saleri, R.; Stefani, C.; Nony, N.; De Luca, L.

    2013-07-01

    The paper will describe a new approach based on the development of a procedural modelling methodology for archaeological data representation. This is a custom-designed solution based on the recognition of the rules belonging to the construction methods used in roman times. We have conceived a tool for 3D reconstruction of masonry structures starting from photogrammetric surveying. Our protocol considers different steps. Firstly we have focused on the classification of opus based on the basic interconnections that can lead to a descriptive system used for their unequivocal identification and design. Secondly, we have chosen an automatic, accurate, flexible and open-source photogrammetric pipeline named Pastis Apero Micmac - PAM, developed by IGN (Paris). We have employed it to generate ortho-images from non-oriented images, using a user-friendly interface implemented by CNRS Marseille (France). Thirdly, the masonry elements are created in parametric and interactive way, and finally they are adapted to the photogrammetric data. The presented application, currently under construction, is developed with an open source programming language called Processing, useful for visual, animated or static, 2D or 3D, interactive creations. Using this computer language, a Java environment has been developed. Therefore, even if the procedural modelling reveals an accuracy level inferior to the one obtained by manual modelling (brick by brick), this method can be useful when taking into account the static evaluation on buildings (requiring quantitative aspects) and metric measures for restoration purposes.

  3. Qualitative mechanism models and the rationalization of procedures

    Science.gov (United States)

    Farley, Arthur M.

    1989-01-01

    A qualitative, cluster-based approach to the representation of hydraulic systems is described and its potential for generating and explaining procedures is demonstrated. Many ideas are formalized and implemented as part of an interactive, computer-based system. The system allows for designing, displaying, and reasoning about hydraulic systems. The interactive system has an interface consisting of three windows: a design/control window, a cluster window, and a diagnosis/plan window. A qualitative mechanism model for the ORS (Orbital Refueling System) is presented to coordinate with ongoing research on this system being conducted at NASA Ames Research Center.

  4. Reproducibility of calibration results by 0-A-0 pressurization procedures for hydraulic pressure transducers

    International Nuclear Information System (INIS)

    Kajikawa, Hiroaki; Kobata, Tokihiko

    2014-01-01

    This paper focuses on 0-A-0 pressurization for the calibration of electromechanical pressure gauges in order to obtain reproducible results by various procedures. In 0-A-0 pressurization, pressure is released to atmospheric pressure after finishing each measurement at each calibration pressure, and the output reading at atmospheric pressure is used for offset correction. Pressure gauges are calibrated under various pressure sequence and time interval conditions in the pressure range of 10 MPa to 100 MPa using a fully automated calibration system that uses a pressure balance as the standard device. Results for a quartz Bourdon-type pressure transducer are mainly reported. The hysteresis obtained by 0-A-0 pressurization is found to be nearly one-tenth of that obtained by stepwise pressurization. The effect of the previously applied pressure is less than 10 parts per million even for a random pressure sequence. Key points for calibration procedures are proposed from the calibration results for different time intervals. When the appropriate procedure is used, 0-A-0 pressurization largely reduces the effect of pressurization history, thus yielding highly reproducible calibration results. (paper)

  5. Blood vessel modeling for interactive simulation of interventional neuroradiology procedures.

    Science.gov (United States)

    Kerrien, E; Yureidini, A; Dequidt, J; Duriez, C; Anxionnat, R; Cotin, S

    2017-01-01

    Endovascular interventions can benefit from interactive simulation in their training phase but also during pre-operative and intra-operative phases if simulation scenarios are based on patient data. A key feature in this context is the ability to extract, from patient images, models of blood vessels that impede neither the realism nor the performance of simulation. This paper addresses both the segmentation and reconstruction of the vasculature from 3D Rotational Angiography data, and adapted to simulation: An original tracking algorithm is proposed to segment the vessel tree while filtering points extracted at the vessel surface in the vicinity of each point on the centerline; then an automatic procedure is described to reconstruct each local unstructured point set as a skeleton-based implicit surface (blobby model). The output of successively applying both algorithms is a new model of vasculature as a tree of local implicit models. The segmentation algorithm is compared with Multiple Hypothesis Testing (MHT) algorithm (Friman et al., 2010) on patient data, showing its greater ability to track blood vessels. The reconstruction algorithm is evaluated on both synthetic and patient data and demonstrate its ability to fit points with a subvoxel precision. Various tests are also reported where our model is used to simulate catheter navigation in interventional neuroradiology. An excellent realism, and much lower computational costs are reported when compared to triangular mesh surface models. Copyright © 2016 Elsevier B.V. All rights reserved.

  6. Hirschsprung's disease and Rehbein's procedure--our results in the last 30 years.

    Science.gov (United States)

    Zganjer, Mirko; Cigit, Irenej; Car, Andrija; Visnjić, Stjepan; Butković, Diana

    2006-12-01

    Hirschsprung's disease is congenital anomaly of the intestine and Harald Hirschsprung gave the first description of this disease'. The aim of this follow-up study was to evaluate the results of Rehbein's procedure in the treatment of Hirschsprung's disease in the last 30 years in Children's Hospital Zagreb. Hirschsprung's disease is congenital intestinal aganglionosis as the results of arrested fetal development of the myenteric nervous system. Hirschsprung's disease is affecting between 1:5000 to 1:8000 live births. A total of 124 children underwent Rehbein's lower anterior resection at Children's Hospital Zagreb. The principle of Rehbein'procedure is to remove aganglionic narrow segment and dilated sigmoid colon and anastomosis between normal intestine with rectal stump. The postoperative outcome was analysed for early and late complications like wound infections, abscesses, anastomotic insufficiency, postoperative enterocolitis, constipation, fecal incontinence, need for reoperation, ileus and mortality. On the basis of our results and data from literature we concluded that Rehbein's procedure is an excellent method for treatment Hirschsprung's disease.

  7. Predictive market segmentation model: An application of logistic regression model and CHAID procedure

    Directory of Open Access Journals (Sweden)

    Soldić-Aleksić Jasna

    2009-01-01

    Full Text Available Market segmentation presents one of the key concepts of the modern marketing. The main goal of market segmentation is focused on creating groups (segments of customers that have similar characteristics, needs, wishes and/or similar behavior regarding the purchase of concrete product/service. Companies can create specific marketing plan for each of these segments and therefore gain short or long term competitive advantage on the market. Depending on the concrete marketing goal, different segmentation schemes and techniques may be applied. This paper presents a predictive market segmentation model based on the application of logistic regression model and CHAID analysis. The logistic regression model was used for the purpose of variables selection (from the initial pool of eleven variables which are statistically significant for explaining the dependent variable. Selected variables were afterwards included in the CHAID procedure that generated the predictive market segmentation model. The model results are presented on the concrete empirical example in the following form: summary model results, CHAID tree, Gain chart, Index chart, risk and classification tables.

  8. Lumping procedure for a kinetic model of catalytic naphtha reforming

    Directory of Open Access Journals (Sweden)

    H. M. Arani

    2009-12-01

    Full Text Available A lumping procedure is developed for obtaining kinetic and thermodynamic parameters of catalytic naphtha reforming. All kinetic and deactivation parameters are estimated from industrial data and thermodynamic parameters are calculated from derived mathematical expressions. The proposed model contains 17 lumps that include the C6 to C8+ hydrocarbon range and 15 reaction pathways. Hougen-Watson Langmuir-Hinshelwood type reaction rate expressions are used for kinetic simulation of catalytic reactions. The kinetic parameters are benchmarked with several sets of plant data and estimated by the SQP optimization method. After calculation of deactivation and kinetic parameters, plant data are compared with model predictions and only minor deviations between experimental and calculated data are generally observed.

  9. Procedures and Methods of Digital Modeling in Representation Didactics

    Science.gov (United States)

    La Mantia, M.

    2011-09-01

    At the Bachelor degree course in Engineering/Architecture of the University "La Sapienza" of Rome, the courses of Design and Survey, in addition to considering the learning of methods of representation, the application of descriptive geometry and survey, in order to expand the vision and spatial conception of the student, pay particular attention to the use of information technology for the preparation of design and survey drawings, achieving their goals through an educational path of "learning techniques, procedures and methods of modeling architectural structures." The fields of application involved two different educational areas: the analysis and that of survey, both from the acquisition of the given metric (design or survey) to the development of three-dimensional virtual model.

  10. Initial tank calibration at NUCEF critical facility. 1. Measurement procedure and its result

    International Nuclear Information System (INIS)

    Yanagisawa, Hiroshi; Mineo, Hideaki; Tonoike, Kotaro; Takeshita, Isao; Hoshi, Katsuya; Hagiwara, Hiroyuki.

    1994-07-01

    Initial tank calibrations were carried out prior to hot operation of critical facilities in NUCEF: Nuclear Fuel Cycle Safety Engineering Research Facility, for the purpose of the nuclear material accountancy and control for the facility. Raw calibration data were collected from single run per one tank by measuring differential pressure with dip-tube systems, weight of calibration liquid (demineralized water) poured into the tank, temperature in the tank and so on, without operation of tank ventilation system. Volume and level data were obtained by applying density and buoyancy corrections to the raw data. As a result, the evaluated measurement errors of volume and level were small enough, e.g. within 0.2 lit. and 1.0 mm, respectively, for Pu accountancy tanks. This paper summarizes the above-mentioned measurement procedures, collected data, data correction procedures and evaluated measurement errors. (author)

  11. Practical approach to a procedure for judging the results of analytical verification measurements

    International Nuclear Information System (INIS)

    Beyrich, W.; Spannagel, G.

    1979-01-01

    For practical safeguards a particularly transparent procedure is described to judge analytical differences between declared and verified values based on experimental data relevant to the actual status of the measurement technique concerned. Essentially it consists of two parts: Derivation of distribution curves for the occurrence of interlaboratory differences from the results of analytical intercomparison programmes; and judging of observed differences using criteria established on the basis of these probability curves. By courtesy of the Euratom Safeguards Directorate, Luxembourg, the applicability of this judging procedure has been checked in practical data verification for safeguarding; the experience gained was encouraging and implementation of the method is intended. Its reliability might be improved further by evaluation of additional experimental data. (author)

  12. Bentall procedure using cryopreserved valved aortic homografts: mid- to long-term results.

    Science.gov (United States)

    Christenson, Jan T; Sierra, Jorge; Trindade, Pedro T; Dominique, Didier; Kalangos, Afksendiyos

    2004-01-01

    The Bentall procedure is the standard operation for patients who have lesions of the ascending aorta associated with aortic valve disease. In many cases, however, mechanical prosthetic conduits are not suitable. There are few reports in the English-language medical literature concerning the mid- to long-term outcome of Bentall operations with cryopreserved homografts. Therefore, we reviewed our experience with this procedure and valved homografts. From January 1997 through December 2002, 21 patients underwent a Bentall operation with cryopreserved homografts at our institution. There were 14 males and 7 females; the mean age was 36 +/- 21 years (range, 15-74 years). Eleven patients had undergone previous aortic valve surgery. All patients had aortic dilatation or aneurysms involving the ascending aorta. Indications for surgery included aortic valve stenosis or insufficiency, and aortic valve endocarditis (native valve or prosthetic). One patient had Takayasu's arteritis and 3 had Marfan syndrome. There was 1 hospital death (due to sepsis), but no other major postoperative complications. The mean hospital stay was 14 +/- 7 days. Follow-up echocardiographic and computed tomographic scans were performed yearly. The mean follow-up was 34 months (6-72 months). Follow-up imaging revealed no calcifications or degenerative processes related to the homograft. Four patients had minimal valve regurgitation. Two patients died during follow-up. The 3-year actuarial survival rate was 85.7%. Our data suggest that the Bentall procedure with a valved homograft conduit is a safe procedure with excellent mid- to long-term results, comparable to results reported with aortic valve replacement with a homograft.

  13. A limited assessment of the ASEP human reliability analysis procedure using simulator examination results

    International Nuclear Information System (INIS)

    Gore, B.R.; Dukelow, J.S. Jr.; Mitts, T.M.; Nicholson, W.L.

    1995-10-01

    This report presents a limited assessment of the conservatism of the Accident Sequence Evaluation Program (ASEP) human reliability analysis (HRA) procedure described in NUREG/CR-4772. In particular, the, ASEP post-accident, post-diagnosis, nominal HRA procedure is assessed within the context of an individual's performance of critical tasks on the simulator portion of requalification examinations administered to nuclear power plant operators. An assessment of the degree to which operator perforn:Lance during simulator examinations is an accurate reflection of operator performance during actual accident conditions was outside the scope of work for this project; therefore, no direct inference can be made from this report about such performance. The data for this study are derived from simulator examination reports from the NRC requalification examination cycle. A total of 4071 critical tasks were identified, of which 45 had been failed. The ASEP procedure was used to estimate human error probability (HEP) values for critical tasks, and the HEP results were compared with the failure rates observed in the examinations. The ASEP procedure was applied by PNL operator license examiners who supplemented the limited information in the examination reports with expert judgment based upon their extensive simulator examination experience. ASEP analyses were performed for a sample of 162 critical tasks selected randomly from the 4071, and the results were used to characterize the entire population. ASEP analyses were also performed for all of the 45 failed critical tasks. Two tests were performed to assess the bias of the ASEP HEPs compared with the data from the requalification examinations. The first compared the average of the ASEP HEP values with the fraction of the population actually failed and it found a statistically significant factor of two bias on the average

  14. A limited assessment of the ASEP human reliability analysis procedure using simulator examination results

    Energy Technology Data Exchange (ETDEWEB)

    Gore, B.R.; Dukelow, J.S. Jr.; Mitts, T.M.; Nicholson, W.L. [Pacific Northwest Lab., Richland, WA (United States)

    1995-10-01

    This report presents a limited assessment of the conservatism of the Accident Sequence Evaluation Program (ASEP) human reliability analysis (HRA) procedure described in NUREG/CR-4772. In particular, the, ASEP post-accident, post-diagnosis, nominal HRA procedure is assessed within the context of an individual`s performance of critical tasks on the simulator portion of requalification examinations administered to nuclear power plant operators. An assessment of the degree to which operator perforn:Lance during simulator examinations is an accurate reflection of operator performance during actual accident conditions was outside the scope of work for this project; therefore, no direct inference can be made from this report about such performance. The data for this study are derived from simulator examination reports from the NRC requalification examination cycle. A total of 4071 critical tasks were identified, of which 45 had been failed. The ASEP procedure was used to estimate human error probability (HEP) values for critical tasks, and the HEP results were compared with the failure rates observed in the examinations. The ASEP procedure was applied by PNL operator license examiners who supplemented the limited information in the examination reports with expert judgment based upon their extensive simulator examination experience. ASEP analyses were performed for a sample of 162 critical tasks selected randomly from the 4071, and the results were used to characterize the entire population. ASEP analyses were also performed for all of the 45 failed critical tasks. Two tests were performed to assess the bias of the ASEP HEPs compared with the data from the requalification examinations. The first compared the average of the ASEP HEP values with the fraction of the population actually failed and it found a statistically significant factor of two bias on the average.

  15. Validation of natural language processing to extract breast cancer pathology procedures and results

    Directory of Open Access Journals (Sweden)

    Arika E Wieneke

    2015-01-01

    Full Text Available Background: Pathology reports typically require manual review to abstract research data. We developed a natural language processing (NLP system to automatically interpret free-text breast pathology reports with limited assistance from manual abstraction. Methods: We used an iterative approach of machine learning algorithms and constructed groups of related findings to identify breast-related procedures and results from free-text pathology reports. We evaluated the NLP system using an all-or-nothing approach to determine which reports could be processed entirely using NLP and which reports needed manual review beyond NLP. We divided 3234 reports for development (2910, 90%, and evaluation (324, 10% purposes using manually reviewed pathology data as our gold standard. Results: NLP correctly coded 12.7% of the evaluation set, flagged 49.1% of reports for manual review, incorrectly coded 30.8%, and correctly omitted 7.4% from the evaluation set due to irrelevancy (i.e. not breast-related. Common procedures and results were identified correctly (e.g. invasive ductal with 95.5% precision and 94.0% sensitivity, but entire reports were flagged for manual review because of rare findings and substantial variation in pathology report text. Conclusions: The NLP system we developed did not perform sufficiently for abstracting entire breast pathology reports. The all-or-nothing approach resulted in too broad of a scope of work and limited our flexibility to identify breast pathology procedures and results. Our NLP system was also limited by the lack of the gold standard data on rare findings and wide variation in pathology text. Focusing on individual, common elements and improving pathology text report standardization may improve performance.

  16. A computational model to investigate assumptions in the headturn preference procedure

    NARCIS (Netherlands)

    Bergmann, C.; Bosch, L.F.M. ten; Fikkert, J.P.M.; Boves, L.W.J.

    2013-01-01

    In this paper we use a computational model to investigate four assumptions that are tacitly present in interpreting the results of studies on infants' speech processing abilities using the Headturn Preference Procedure (HPP): (1) behavioral differences originate in different processing; (2)

  17. Immediate results of aortic valve reconstruction by using autologous pericardium (Ozaki procedure

    Directory of Open Access Journals (Sweden)

    Е. В. Россейкин

    2016-08-01

    Full Text Available Aim: The study was designed to compare the immediate echocardiographic characteristics of aortic valve reconstruction by using autologous pericardium and the method proposed in 2007 by Shigeyuki Ozaki, as well as aortic valve replacement by means of frame-mounted biological prostheses Medtronic HANCOCK®II T505 CINCH® II and the Carpentier-Edwards PERIMOUNT.Methods: Over a period from January 2014 to February 2016, 76 patients underwent aortic valve replacement by means of frame-mounted biological prostheses Medtronic HANCOCK®II T505 CINCH® II (n=41 and Carpentier-Edwards PERIMOUNT (n=35 at our hospital. 20 patients underwent the Ozaki procedure. These three groups of patients were assigned to the study. Demographic and preoperative indicators of patients from all three groups were homogeneous (р>0.05. The evaluation of the aortic valves replaced was carried out by echocardiography.Results: Echocardiography was performed before the procedure and in the early postoperative period. Statistical analysis using ANOVA showed significantly lower values of the aortic valve pressure gradient (p<0.001 and larger effective orifice area and indexed effective orifice area of the valve (p<0.001 in the group of the Ozaki procedure.Conclusion: According to echocardiography data, in the immediate postoperative period the Ozaki procedure is associated with lower mean and peak gradients of pressure on the aortic valve and larger effective orifice area and indexed effective orifice area of the valve, as compared with the frame-mounted biological aortic prostheses Medtronic HANCOCK®II T505 CINCH® II and the Carpentier-Edwards PERIMOUNT.FundingThe study had no sponsorship.Conflict of interestThe authors declare no conflict of interest.

  18. Immediate results of aortic valve reconstruction by using autologous pericardium (Ozaki procedure

    Directory of Open Access Journals (Sweden)

    Е. В. Россейкин

    2016-11-01

    Full Text Available Aim. The study was designed to compare the immediate echocardiographic characteristics of aortic valve reconstruction by using autologous pericardium and the method proposed in 2007 by Shigeyuki Ozaki, as well as aortic valve replacement by means of frame-mounted biological prostheses Medtronic HANCOCK®II T505 CINCH® II and the Carpentier-Edwards PERIMOUNT.Methods. Over a period from January 2014 to February 2016, 76 patients underwent aortic valve replacement by means of frame-mounted biological prostheses Medtronic HANCOCK®II T505 CINCH® II (n=41 and Carpentier-Edwards PERIMOUNT (n=35 at our hospital. 20 patients underwent the Ozaki procedure. These three groups of patients were assigned to the study. Demographic and preoperative indicators of patients from all three groups were homogeneous (р>0.05. The evaluation of the aortic valves replaced was carried out by echocardiography.Results. Echocardiography was performed before the procedure and in the early postoperative period. Statistical analysis using ANOVA showed significantly lower values of the aortic valve pressure gradient (p<0.001 and larger effective orifice area and indexed effective orifice area of the valve (p<0.001 in the group of the Ozaki procedure.Conclusion. According to echocardiography data, in the immediate postoperative period the Ozaki procedure is associated with lower mean and peak gradients of pressure on the aortic valve and larger effective orifice area and indexed effective orifice area of the valve, as compared with the frame-mounted biological aortic prostheses Medtronic HANCOCK®II T505 CINCH® II and the Carpentier-Edwards PERIMOUNT.Received 27 May 2016. Accepted 24 June 2016.Funding: The study had no sponsorship. Conflict of interest: The authors declare no conflict of interest.

  19. CT-guided vertebroplasty: analysis of technical results, extraosseous cement leakages, and complications in 500 procedures

    Energy Technology Data Exchange (ETDEWEB)

    Pitton, Michael Bernhard; Herber, Sascha; Koch, Ulrike; Oberholzer, Katja; Dueber, Christoph [Johannes Gutenberg-University of Mainz, Department of Diagnostic and Interventional Radiology, Mainz (Germany); Drees, Philip [University Hospital, Johannes Gutenberg-University of Mainz, Department of Orthopedic Surgery, Mainz (Germany)

    2008-11-15

    The aim of this study was to analyze the technical results, the extraosseous cement leakages, and the complications in our first 500 vertebroplasty procedures. Patients with osteoporotic vertebral compression fractures or osteolytic lesions caused by malignant tumors were treated with CT-guided vertebroplasty. The technical results were documented with CT, and the extraosseous cement leakages and periinterventional clinical complications were analyzed as well as secondary fractures during follow-up. Since 2002, 500 vertebroplasty procedures have been performed on 251 patients (82 male, 169 female, age 71.5 {+-} 9.8 years) suffering from osteoporotic compression fractures (n = 217) and/or malignant tumour infiltration (n = 34). The number of vertebrae treated per patient was 1.96 {+-} 1.29 (range 1-10); the numbers of interventions per patient and interventions per vertebra were 1.33 {+-} 0.75 (range 1-6) and 1.01 {+-} 0.10, respectively. The amount of PMMA cement was 4.5 {+-} 1.9 ml and decreased during the 5-year period of investigation. The procedure-related 30-day mortality was 0.4% (1 of 251 patients) due to pulmonary embolism in this case. The procedure-related morbidity was 2.8% (7/251), including one acute coronary syndrome beginning 12 h after the procedure and one missing patellar reflex in a patients with a cement leak near the neuroformen because of osteolytic destruction of the respective pedicle. Additionally, one patient developed a medullary conus syndrome after a fall during the night after vertebroplasty, two patients reached an inadequate depth of conscious sedation, and two cases had additional fractures (one pedicle fracture, one rib fracture). The overall CT-based cement leak rate was 55.4% and included leakages predominantly into intervertebral disc spaces (25.2%), epidural vein plexus (16.0%), through the posterior wall (2.6%), into the neuroforamen (1.6%), into paravertebral vessels (7.2%), and combinations of these and others. During follow

  20. State Token Petri Net modeling method for formal verification of computerized procedure including operator's interruptions of procedure execution flow

    International Nuclear Information System (INIS)

    Kim, Yun Goo; Seong, Poong Hyun

    2012-01-01

    The Computerized Procedure System (CPS) is one of the primary operating support systems in the digital Main Control Room. The CPS displays procedure on the computer screen in the form of a flow chart, and displays plant operating information along with procedure instructions. It also supports operator decision making by providing a system decision. A procedure flow should be correct and reliable, as an error would lead to operator misjudgement and inadequate control. In this paper we present a modeling for the CPS that enables formal verification based on Petri nets. The proposed State Token Petri Nets (STPN) also support modeling of a procedure flow that has various interruptions by the operator, according to the plant condition. STPN modeling is compared with Coloured Petri net when they are applied to Emergency Operating Computerized Procedure. A converting program for Computerized Procedure (CP) to STPN has been also developed. The formal verification and validation methods of CP with STPN increase the safety of a nuclear power plant and provide digital quality assurance means that are needed when the role and function of the CPS is increasing.

  1. Developing Physiologic Models for Emergency Medical Procedures Under Microgravity

    Science.gov (United States)

    Parker, Nigel; O'Quinn, Veronica

    2012-01-01

    Several technological enhancements have been made to METI's commercial Emergency Care Simulator (ECS) with regard to how microgravity affects human physiology. The ECS uses both a software-only lung simulation, and an integrated mannequin lung that uses a physical lung bag for creating chest excursions, and a digital simulation of lung mechanics and gas exchange. METI s patient simulators incorporate models of human physiology that simulate lung and chest wall mechanics, as well as pulmonary gas exchange. Microgravity affects how O2 and CO2 are exchanged in the lungs. Procedures were also developed to take into affect the Glasgow Coma Scale for determining levels of consciousness by varying the ECS eye-blinking function to partially indicate the level of consciousness of the patient. In addition, the ECS was modified to provide various levels of pulses from weak and thready to hyper-dynamic to assist in assessing patient conditions from the femoral, carotid, brachial, and pedal pulse locations.

  2. Results of steel containment vessel model test

    International Nuclear Information System (INIS)

    Luk, V.K.; Ludwigsen, J.S.; Hessheimer, M.F.; Komine, Kuniaki; Matsumoto, Tomoyuki; Costello, J.F.

    1998-05-01

    A series of static overpressurization tests of scale models of nuclear containment structures is being conducted by Sandia National Laboratories for the Nuclear Power Engineering Corporation of Japan and the US Nuclear Regulatory Commission. Two tests are being conducted: (1) a test of a model of a steel containment vessel (SCV) and (2) a test of a model of a prestressed concrete containment vessel (PCCV). This paper summarizes the conduct of the high pressure pneumatic test of the SCV model and the results of that test. Results of this test are summarized and are compared with pretest predictions performed by the sponsoring organizations and others who participated in a blind pretest prediction effort. Questions raised by this comparison are identified and plans for posttest analysis are discussed

  3. Experiences with a procedure for modeling product knowledge

    DEFF Research Database (Denmark)

    Hansen, Benjamin Loer; Hvam, Lars

    2002-01-01

    This paper presents experiences with a procedure for building configurators. The procedure has been used in an American company producing custom-made precision air conditioning equipment. The paper describes experiences with the use of the procedure and experiences with the project in general....

  4. A physiological production model for cacao : results of model simulations

    NARCIS (Netherlands)

    Zuidema, P.A.; Leffelaar, P.A.

    2002-01-01

    CASE2 is a physiological model for cocoa (Theobroma cacao L.) growth and yield. This report introduces the CAcao Simulation Engine for water-limited production in a non-technical way and presents simulation results obtained with the model.

  5. Enhancing paramedics procedural skills using a cadaveric model.

    Science.gov (United States)

    Lim, David; Bartlett, Stephen; Horrocks, Peter; Grant-Wakefield, Courtenay; Kelly, Jodie; Tippett, Vivienne

    2014-07-08

    Paramedic education has evolved in recent times from vocational post-employment to tertiary pre-employment supplemented by clinical placement. Simulation is advocated as a means of transferring learned skills to clinical practice. Sole reliance of simulation learning using mannequin-based models may not be sufficient to prepare students for variance in human anatomy. In 2012, we trialled the use of fresh frozen human cadavers to supplement undergraduate paramedic procedural skill training. The purpose of this study is to evaluate whether cadaveric training is an effective adjunct to mannequin simulation and clinical placement. A multi-method approach was adopted. The first step involved a Delphi methodology to formulate and validate the evaluation instrument. The instrument comprised of knowledge-based MCQs, Likert for self-evaluation of procedural skills and behaviours, and open answer. The second step involved a pre-post evaluation of the 2013 cadaveric training. One hundred and fourteen students attended the workshop and 96 evaluations were included in the analysis, representing a return rate of 84%. There was statistically significant improved anatomical knowledge after the workshop. Students' self-rated confidence in performing procedural skills on real patients improved significantly after the workshop: inserting laryngeal mask (MD 0.667), oropharyngeal (MD 0.198) and nasopharyngeal (MD 0.600) airways, performing Bag-Valve-Mask (MD 0.379), double (MD 0.344) and triple (MD 0.326,) airway manoeuvre, doing 12-lead electrocardiography (MD 0.729), using laryngoscope (MD 0.726), using Magill® forceps to remove foreign body (MD 0.632), attempting thoracocentesis (MD 1.240), and putting on a traction splint (MD 0.865). The students commented that the workshop provided context to their theoretical knowledge and that they gained an appreciation of the differences in normal tissue variation. Following engagement in/ completion of the workshop, students were more aware

  6. Summary of FY15 results of benchmark modeling activities

    Energy Technology Data Exchange (ETDEWEB)

    Arguello, J. Guadalupe [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States)

    2015-08-01

    Sandia is participating in the third phase of an is a contributing partner to a U.S.-German "Joint Project" entitled "Comparison of current constitutive models and simulation procedures on the basis of model calculations of the thermo-mechanical behavior and healing of rock salt." The first goal of the project is to check the ability of numerical modeling tools to correctly describe the relevant deformation phenomena in rock salt under various influences. Achieving this goal will lead to increased confidence in the results of numerical simulations related to the secure storage of radioactive wastes in rock salt, thereby enhancing the acceptance of the results. These results may ultimately be used to make various assertions regarding both the stability analysis of an underground repository in salt, during the operating phase, and the long-term integrity of the geological barrier against the release of harmful substances into the biosphere, in the post-operating phase.

  7. Using genetic algorithm and TOPSIS for Xinanjiang model calibration with a single procedure

    Science.gov (United States)

    Cheng, Chun-Tian; Zhao, Ming-Yan; Chau, K. W.; Wu, Xin-Yu

    2006-01-01

    Genetic Algorithm (GA) is globally oriented in searching and thus useful in optimizing multiobjective problems, especially where the objective functions are ill-defined. Conceptual rainfall-runoff models that aim at predicting streamflow from the knowledge of precipitation over a catchment have become a basic tool for flood forecasting. The parameter calibration of a conceptual model usually involves the multiple criteria for judging the performances of observed data. However, it is often difficult to derive all objective functions for the parameter calibration problem of a conceptual model. Thus, a new method to the multiple criteria parameter calibration problem, which combines GA with TOPSIS (technique for order performance by similarity to ideal solution) for Xinanjiang model, is presented. This study is an immediate further development of authors' previous research (Cheng, C.T., Ou, C.P., Chau, K.W., 2002. Combining a fuzzy optimal model with a genetic algorithm to solve multi-objective rainfall-runoff model calibration. Journal of Hydrology, 268, 72-86), whose obvious disadvantages are to split the whole procedure into two parts and to become difficult to integrally grasp the best behaviors of model during the calibration procedure. The current method integrates the two parts of Xinanjiang rainfall-runoff model calibration together, simplifying the procedures of model calibration and validation and easily demonstrated the intrinsic phenomenon of observed data in integrity. Comparison of results with two-step procedure shows that the current methodology gives similar results to the previous method, is also feasible and robust, but simpler and easier to apply in practice.

  8. 49 CFR 219.611 - Test result indicating prohibited alcohol concentration; procedures.

    Science.gov (United States)

    2010-10-01

    ... concentration; procedures. 219.611 Section 219.611 Transportation Other Regulations Relating to Transportation... concentration; procedures. Procedures for administrative handling by the railroad in the event an employee's confirmation test indicates an alcohol concentration of .04 or greater are set forth in § 219.104. ...

  9. Long-term results of modified Bentall procedure using flanged composite aortic prosthesis.

    Science.gov (United States)

    Tamura, Kiyoshi; Arai, Hirokuni; Kawaguchi, Satoru; Makita, Satoru; Miyagi, Naoto; Watanabe, Taiju; Fujiwara, Tatsuki

    2013-01-01

    We have been using the flanged composite aortic prosthesis and Carrel button technique to re-attach the coronary ostia in aortic root replacement procedures at our institution over the last twenty five years. Our objective was to evaluate the long-term results of aortic root replacement with this technique. A total of 73 patients from January 1984 to August 2010 were included in this study. The median age was 52.7 ± 14.4 years (range 28-80 years). There were 48 male and 25 female patients. 44 patients (60.3%) had annuloaortic ectasia, and 15 patients (20.5%) had acute type A aortic dissection. Marfan syndrome was recognized in 12 patients (16.5%). The early mortality rate was 5.5% (n = 4). Causes of death were multiple organ failures in two patients and sepsis in another two patients. The actuarial survival rate was 84.2% at 5 years, 64.3% at 15 years and 51.9% at 25 years. Only one patient with aortitis needed a reoperation because of coronary pseudoaneurysm after 23 years from the previous operation. This modified Bentall procedure is reliable and safe, with superior long-term survival and a low rate of aortic reoperation.

  10. Late Results of Cox Maze III Procedure in Patients with Atrial Fibrillation Associated with Structural Heart Disease

    Directory of Open Access Journals (Sweden)

    Gustavo Gir Gomes

    Full Text Available Abstract Background: Cox-Maze III procedure is one of the surgical techniques used in the surgical treatment of atrial fibrillation (AF. Objectives: To determine late results of Cox-Maze III in terms of maintenance of sinus rhythm, and mortality and stroke rates. Methods: Between January 2006 and January 2013, 93 patients were submitted to the cut-and-sew Cox-Maze III procedure in combination with structural heart disease repair. Heart rhythm was determined by 24-hour Holter monitoring. Procedural success rates were determined by longitudinal methods and recurrence predictors by multivariate Cox regression models. Results: Thirteen patients that obtained hospital discharge alive were excluded due to lost follow-up. The remaining 80 patients were aged 49.9 ± 12 years and 47 (58.7% of them were female. Involvement of mitral valve and rheumatic heart disease were found in 67 (83.7% and 63 (78.7% patients, respectively. Seventy patients (87.5% had persistent or long-standing persistent AF. Mean follow-up with Holter monitoring was 27.5 months. There were no hospital deaths. Sinus rhythm maintenance rates were 88%, 85.1% and 80.6% at 6 months, 24 months and 36 months, respectively. Predictors of late recurrence of AF were female gender (HR 3.52; 95% CI 1.21-10.25; p = 0.02, coronary artery disease (HR 4.73 95% CI 1.37-16.36; p = 0.01 and greater left atrium diameter (HR 1.05; 95% CI 1.01-1.09; p = 0.02. Actuarial survival was 98.5% at 12, 24 and 48 months and actuarial freedom from stroke was 100%, 100% and 97.5% in the same time frames. Conclusions: The Cox-Maze III procedure, in our experience, is efficacious for sinus rhythm maintenance, with very low late mortality and stroke rates.

  11. Procedural 3d Modelling for Traditional Settlements. The Case Study of Central Zagori

    Science.gov (United States)

    Kitsakis, D.; Tsiliakou, E.; Labropoulos, T.; Dimopoulou, E.

    2017-02-01

    Over the last decades 3D modelling has been a fast growing field in Geographic Information Science, extensively applied in various domains including reconstruction and visualization of cultural heritage, especially monuments and traditional settlements. Technological advances in computer graphics, allow for modelling of complex 3D objects achieving high precision and accuracy. Procedural modelling is an effective tool and a relatively novel method, based on algorithmic modelling concept. It is utilized for the generation of accurate 3D models and composite facade textures from sets of rules which are called Computer Generated Architecture grammars (CGA grammars), defining the objects' detailed geometry, rather than altering or editing the model manually. In this paper, procedural modelling tools have been exploited to generate the 3D model of a traditional settlement in the region of Central Zagori in Greece. The detailed geometries of 3D models derived from the application of shape grammars on selected footprints, and the process resulted in a final 3D model, optimally describing the built environment of Central Zagori, in three levels of Detail (LoD). The final 3D scene was exported and published as 3D web-scene which can be viewed with 3D CityEngine viewer, giving a walkthrough the whole model, same as in virtual reality or game environments. This research work addresses issues regarding textures' precision, LoD for 3D objects and interactive visualization within one 3D scene, as well as the effectiveness of large scale modelling, along with the benefits and drawbacks that derive from procedural modelling techniques in the field of cultural heritage and more specifically on 3D modelling of traditional settlements.

  12. Indications for and clinical procedures resulting from magnetic resonance imaging of the knee in older patients

    Science.gov (United States)

    Parent, Marc-Etienne; Vézina, François; Carrier, Nathalie; Masetto, Ariel

    2018-01-01

    Abstract Objective To analyze the indications for and clinical procedures resulting from knee magnetic resonance imaging (MRI) in older patients. Design We retrospectively analyzed 215 medical records of patients 50 years of age and older who had undergone a unilateral knee MRI in 2009. Setting Centre hospitalier universitaire de Sherbrooke in Quebec. Participants Patients 50 years of age and older who underwent a knee MRI in 2009. Main outcome measures The main outcome measure was an invasive procedure in the same knee that underwent an MRI. Medical charts were reviewed up to 2014 for patient characteristics, MRI indication, ordering physician specialty, radiography before MRI, MRI findings, and clinical procedures resulting from the MRI. Results The patients’ mean (SD) age was 60.6 (7.5) years. The main MRI indications were meniscopathy (148 [68.8%]) and chronic pain (92 [42.8%]). The main MRI findings were osteoarthritis (OA) (185 [86.0%]) and meniscal lesions (170 [79.1%]). Only 82 (38.1%) patients had a plain radiograph in the 24 months preceding the MRI, usually without a standing anteroposterior view. Findings on pre-MRI radiography (n = 201) demonstrated OA in 144 (71.6%) patients. Overall, 87 (40.5%) patients were seen by an orthopedic surgeon and 27 (31.0%) of these patients underwent an invasive intervention. Among the 81 patients with moderate to severe OA on MRI, 36 (44.4%) had radiographic evidence of moderate to severe OA and only 3 (3.7%) underwent arthroscopic meniscectomy. Conclusion Our study reproduces the known association between OA and degenerative meniscal changes in older patients. We have found a surprising underuse of the standing anteroposterior view on radiography. Most patients in our cohort could have been appropriately diagnosed and treated based on such radiographic information, as demonstrated by pre-MRI findings, thus avoiding the MRI and subsequent evaluation by an orthopedic surgeon. Meniscectomy was rarely performed

  13. Recurrent Anterior Shoulder Instability With Combined Bone Loss: Treatment and Results With the Modified Latarjet Procedure.

    Science.gov (United States)

    Yang, Justin S; Mazzocca, Augustus D; Cote, Mark P; Edgar, Cory M; Arciero, Robert A

    2016-04-01

    Recurrent anterior glenohumeral dislocation in the setting of an engaging Hill-Sachs lesion is high. The Latarjet procedure has been well described for restoring glenohumeral stability in patients with >25% glenoid bone loss. However, the treatment for patients with combined humeral head and mild (Latarjet for patients with combined humeral and glenoid defects and compares the results for patients with ≤25% glenoid bone loss versus patients with >25% glenoid bone loss. The hypothesis was that the 2 groups would have equivalent subjective outcomes and recurrence rates. Cohort Study; Level of evidence, 3. Modified Latarjet was performed in 40 patients with recurrent anterior shoulder instability, engaging Hill-Sachs by examination confirmed with arthroscopy, and ≤25% anterior glenoid bone loss (group A). A second group of 12 patients were identified to have >25% glenoid bone loss with an engaging Hill-Sachs lesion (group B). The mean follow-up time was 3.5 years. All patients were assessed for their risk of recurrence using the Instability Severity Index score and Beighton score and had preoperative 3-dimensional imaging to assess humeral and glenoid bone loss. Single Assessment Numeric Evaluation (SANE), Western Ontario Shoulder Instability Index (WOSI), recurrence rate, radiographs, range of motion, and dynamometer strength were used to assess outcomes. A multivariate analysis was performed. Glenoid bone loss averaged 15% in group A compared with 34% in group B. Both groups had comparable WOSI scores (356 vs 475; P = .311). In multivariate analysis, the number of previous surgeries and Beighton score were directly correlated with WOSI score in Latarjet patients. The SANE score was better in group A (86 vs 77; P = .02). Group B experienced more loss of external rotation (9.2° vs 15.8°; P = .0001) and weaker thumbs-down abduction and external rotation strength (P .999) were similar for both groups. The complication rate was 25% for both groups. The modified

  14. Marginal production in the Gulf of Mexico - II. Model results

    International Nuclear Information System (INIS)

    Kaiser, Mark J.; Yu, Yunke

    2010-01-01

    In the second part of this two-part article on marginal production in the Gulf of Mexico, we estimate the number of committed assets in water depth less than 1000 ft that are expected to be marginal over a 60-year time horizon. We compute the expected quantity and value of the production and gross revenue streams of the gulf's committed asset inventory circa. January 2007 using a probabilistic model framework. Cumulative hydrocarbon production from the producing inventory is estimated to be 1056 MMbbl oil and 13.3 Tcf gas. Marginal production from the committed asset inventory is expected to contribute 4.1% of total oil production and 5.4% of gas production. A meta-evaluation procedure is adapted to present the results of sensitivity analysis. Model results are discussed along with a description of the model framework and limitations of the analysis. (author)

  15. Marginal production in the Gulf of Mexico - II. Model results

    Energy Technology Data Exchange (ETDEWEB)

    Kaiser, Mark J.; Yu, Yunke [Center for Energy Studies, Louisiana State University, Baton Rouge, LA 70803 (United States)

    2010-08-15

    In the second part of this two-part article on marginal production in the Gulf of Mexico, we estimate the number of committed assets in water depth less than 1000 ft that are expected to be marginal over a 60-year time horizon. We compute the expected quantity and value of the production and gross revenue streams of the gulf's committed asset inventory circa. January 2007 using a probabilistic model framework. Cumulative hydrocarbon production from the producing inventory is estimated to be 1056 MMbbl oil and 13.3 Tcf gas. Marginal production from the committed asset inventory is expected to contribute 4.1% of total oil production and 5.4% of gas production. A meta-evaluation procedure is adapted to present the results of sensitivity analysis. Model results are discussed along with a description of the model framework and limitations of the analysis. (author)

  16. 49 CFR 40.247 - What procedures does the BAT or STT follow after a screening test result?

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false What procedures does the BAT or STT follow after a... What procedures does the BAT or STT follow after a screening test result? (a) If the test result is an alcohol concentration of less than 0.02, as the BAT or STT, you must do the following: (1) Sign and date...

  17. Procedure for identifying models for the heat dynamics of buildings

    DEFF Research Database (Denmark)

    Bacher, Peder; Madsen, Henrik

    This report describes a new method for obtaining detailed information about the heat dynamics of a building using frequent reading of the heat consumption. Such a procedure is considered to be of uttermost importance as a key procedure for using readings from smart meters, which is expected...

  18. A P-value model for theoretical power analysis and its applications in multiple testing procedures

    Directory of Open Access Journals (Sweden)

    Fengqing Zhang

    2016-10-01

    Full Text Available Abstract Background Power analysis is a critical aspect of the design of experiments to detect an effect of a given size. When multiple hypotheses are tested simultaneously, multiplicity adjustments to p-values should be taken into account in power analysis. There are a limited number of studies on power analysis in multiple testing procedures. For some methods, the theoretical analysis is difficult and extensive numerical simulations are often needed, while other methods oversimplify the information under the alternative hypothesis. To this end, this paper aims to develop a new statistical model for power analysis in multiple testing procedures. Methods We propose a step-function-based p-value model under the alternative hypothesis, which is simple enough to perform power analysis without simulations, but not too simple to lose the information from the alternative hypothesis. The first step is to transform distributions of different test statistics (e.g., t, chi-square or F to distributions of corresponding p-values. We then use a step function to approximate each of the p-value’s distributions by matching the mean and variance. Lastly, the step-function-based p-value model can be used for theoretical power analysis. Results The proposed model is applied to problems in multiple testing procedures. We first show how the most powerful critical constants can be chosen using the step-function-based p-value model. Our model is then applied to the field of multiple testing procedures to explain the assumption of monotonicity of the critical constants. Lastly, we apply our model to a behavioral weight loss and maintenance study to select the optimal critical constants. Conclusions The proposed model is easy to implement and preserves the information from the alternative hypothesis.

  19. Management of persistent coccydynia with transrectal manipulation: results of a combined procedure.

    Science.gov (United States)

    Seker, Ali; Sarikaya, Ilker Abdullah; Korkmaz, Ozgur; Yalcin, Sercan; Malkoc, Melih; Bulbul, Ahmet Murat

    2017-12-12

    We compared the results of manual therapy combined with steroid injection with single steroid injection in the treatment of persistent coccydynia. Combined therapy was performed in 21 patients (Group 1) and steroid injection in 23 patients (Group 2). We compared two groups and investigated the combined therapy group in details. Patients were classified according to the underlying cause, BMI, anatomic type of coccyx and duration of symptoms (< 6 or ≥ 6 months). Mean age was 30.5 years at the time of procedures. Mean followup time was 27.8 months. VAS scores were decreased in both groups but combined therapy group had much more better results. Complete pain relief was achieved in 61.9% of patients in Group 1 whereas it was only 17.4% in Group 2. In 23.8% of Group 1, the VAS score was significantly decreased but the feeling of uncomfortability persisted. This was 73.9% in Group 2. We had no relapse in Group 1 but in Group 2 the relapse rate was 56.5%. Underlying cause, body mass index, anatomic type of coccyx and duration of symptoms had no effect on results. Manual therapy combined with steroid injection would be an alternative method in case of persistent coccydynia. It is a safe and easy option before surgical treatment.

  20. A Two-Dimensional Modeling Procedure to Estimate the Loss Equivalent Resistance Including the Saturation Effect

    Directory of Open Access Journals (Sweden)

    Rosa Ana Salas

    2013-11-01

    Full Text Available We propose a modeling procedure specifically designed for a ferrite inductor excited by a waveform in time domain. We estimate the loss resistance in the core (parameter of the electrical model of the inductor by means of a Finite Element Method in 2D which leads to significant computational advantages over the 3D model. The methodology is validated for an RM (rectangular modulus ferrite core working in the linear and the saturation regions. Excellent agreement is found between the experimental data and the computational results.

  1. Information matrix estimation procedures for cognitive diagnostic models.

    Science.gov (United States)

    Liu, Yanlou; Xin, Tao; Andersson, Björn; Tian, Wei

    2018-03-06

    Two new methods to estimate the asymptotic covariance matrix for marginal maximum likelihood estimation of cognitive diagnosis models (CDMs), the inverse of the observed information matrix and the sandwich-type estimator, are introduced. Unlike several previous covariance matrix estimators, the new methods take into account both the item and structural parameters. The relationships between the observed information matrix, the empirical cross-product information matrix, the sandwich-type covariance matrix and the two approaches proposed by de la Torre (2009, J. Educ. Behav. Stat., 34, 115) are discussed. Simulation results show that, for a correctly specified CDM and Q-matrix or with a slightly misspecified probability model, the observed information matrix and the sandwich-type covariance matrix exhibit good performance with respect to providing consistent standard errors of item parameter estimates. However, with substantial model misspecification only the sandwich-type covariance matrix exhibits robust performance. © 2018 The British Psychological Society.

  2. Presentation of automated procedural guidance in surgical simulation: results of two randomised controlled trials.

    Science.gov (United States)

    Wijewickrema, S; Zhou, Y; Ioannou, I; Copson, B; Piromchai, P; Yu, C; Briggs, R; Bailey, J; Kennedy, G; O'Leary, S

    2018-03-01

    To investigate the effectiveness and usability of automated procedural guidance during virtual temporal bone surgery. Two randomised controlled trials were performed to evaluate the effectiveness, for medical students, of two presentation modalities of automated real-time procedural guidance in virtual reality simulation: full and step-by-step visual presentation of drillable areas. Presentation modality effectiveness was determined through a comparison of participants' dissection quality, evaluated by a blinded otologist, using a validated assessment scale. While the provision of automated guidance on procedure improved performance (full presentation, p = 0.03; step-by-step presentation, p presentation modalities was vastly different (full presentation, 3.73 per cent; step-by-step presentation, 60.40 per cent). Automated procedural guidance in virtual temporal bone surgery is effective in improving trainee performance. Step-by-step presentation of procedural guidance was engaging, and therefore more likely to be used by the participants.

  3. Vacuum-assisted biopsies under MR guidance: results of 72 procedures

    Energy Technology Data Exchange (ETDEWEB)

    Malhaire, C.; El Khoury, C.; Thibault, F.; Athanasiou, A.; Petrow, P.; Ollivier, L.; Tardivon, A. [Institut Curie, Radiology Department, Paris (France)

    2010-07-15

    To investigate the clinical accuracy of magnetic resonance imaging-guided breast vacuum-assisted biopsy (MR-VAB). Of 97 scheduled MR-VAB for single MRI lesions (negative second-look sonography) categorised as BI-RADS 4 or 5, 4 were cancelled (undetected lesion = 2, technical problems = 2). Twenty-one patients lost to follow-up were excluded. Twenty-three patients (median age 51 years) were at high risk (BRCA1 = 11, BRCA2 = 7, familial risk = 5), 23 had a suspected local recurrence of breast cancer. Seventy-two imaged lesions (focus = 1, mass enhancement = 32, non-mass-like enhancement = 39) were targeted with a 10-gauge VAB probe using MRI guidance, with a median of 18 specimens per lesion (median procedural time 72 min, range 50-131 min) followed by clip placement. In the case of benignity, MRI follow-up was performed (19 patients, median 389 days, range 33-1,592) or mammography (3 patients, median 420 days, range 372-1,354). According to histopathology results, 29 lesions were benign, 10 were high-risk (papillary = 2, radial scar = 1, atypical epithelial hyperplasia = 7) and 33 malignant (ductal carcinoma in situ = 8, invasive cancers = 25). Three false negative results and 3 complications occurred (1 malaise, 1 skin defect, 1 infection). MRI-guided VAB represents an accurate tool for the histological diagnosis of lesions visible only at MRI. (orig.)

  4. Continuous integrity evaluation of corroded pipelines using complemented FEA results – Part II: Procedure application

    International Nuclear Information System (INIS)

    Varga, László; Fekete, Gábor

    2017-01-01

    The general objective of this paper is to execute the continuous integrity evaluation of corroded pipelines with the developed procedure has been presented in the Part I. This aim was performed with a large dataset of complemented finite element analysis (FEA) results and burst test values can be found in the References. The numerical investigations have been done with an assumed sample-case taking spherical and spheroid shaped characteristic and mobile defects into account. The most important achievements are the supplemented ductile failure analysis, the continuous suitability of the weak link, the strain-based design criteria and the continuous integrity assessment diagrams. - Highlights: • Finite Element Analysis (FEA) examinations are performed for selection of a sample-case to investigate corrosion defects. • Serial calculations are carried out to determine the continuous suitability of the corroded pipeline sections. • We investigate the shape and size effects of corrosion defects on load carrying capacities (LCCs) of defective pipelines. • Continuous integrity assessment diagram (CIAD) showing the decreasing competent LCCs in the operation time is introduced. • Verification of the proposed method is performed by comparing the FEA results with burst pressure values measured.

  5. A Procedure for Modeling Photovoltaic Arrays under Any Configuration and Shading Conditions

    Directory of Open Access Journals (Sweden)

    Daniel Gonzalez Montoya

    2018-03-01

    Full Text Available Photovoltaic (PV arrays can be connected following regular or irregular connection patterns to form regular configurations (e.g., series-parallel, total cross-tied, bridge-linked, etc. or irregular configurations, respectively. Several reported works propose models for a single configuration; hence, making the evaluation of arrays with different configuration is a considerable time-consuming task. Moreover, if the PV array adopts an irregular configuration, the classical models cannot be used for its analysis. This paper proposes a modeling procedure for PV arrays connected in any configuration and operating under uniform or partial shading conditions. The procedure divides the array into smaller arrays, named sub-arrays, which can be independently solved. The modeling procedure selects the mesh current solution or the node voltage solution depending on the topology of each sub-array. Therefore, the proposed approach analyzes the PV array using the least number of nonlinear equations. The proposed solution is validated through simulation and experimental results, which demonstrate the proposed model capacity to reproduce the electrical behavior of PV arrays connected in any configuration.

  6. Visual perception of procedural textures: identifying perceptual dimensions and predicting generation models.

    Directory of Open Access Journals (Sweden)

    Jun Liu

    Full Text Available Procedural models are widely used in computer graphics for generating realistic, natural-looking textures. However, these mathematical models are not perceptually meaningful, whereas the users, such as artists and designers, would prefer to make descriptions using intuitive and perceptual characteristics like "repetitive," "directional," "structured," and so on. To make up for this gap, we investigated the perceptual dimensions of textures generated by a collection of procedural models. Two psychophysical experiments were conducted: free-grouping and rating. We applied Hierarchical Cluster Analysis (HCA and Singular Value Decomposition (SVD to discover the perceptual features used by the observers in grouping similar textures. The results suggested that existing dimensions in literature cannot accommodate random textures. We therefore utilized isometric feature mapping (Isomap to establish a three-dimensional perceptual texture space which better explains the features used by humans in texture similarity judgment. Finally, we proposed computational models to map perceptual features to the perceptual texture space, which can suggest a procedural model to produce textures according to user-defined perceptual scales.

  7. Interpretation of surface water monitoring results in the authorisation procedure of plant protection products in the Netherlands

    NARCIS (Netherlands)

    Werd, de H.A.E.; Kruijne, R.

    2011-01-01

    As part of the ‘Surface Waters Decision Tree’ project a new authorisation procedure for plant protection products (PPPs) has been developed. The feedback of monitoring results in the authorisation procedure consists of 3 main steps: 1. Identification and ranking of problematic substances 2. Analysis

  8. Numerical study of RF exposure and the resulting temperature rise in the foetus during a magnetic resonance procedure

    International Nuclear Information System (INIS)

    Hand, J W; Li, Y; Hajnal, J V

    2010-01-01

    Numerical simulations of specific absorption rate (SAR) and temperature changes in a 26-week pregnant woman model within typical birdcage body coils as used in 1.5 T and 3 T MRI scanners are described. Spatial distributions of SAR and the resulting spatial and temporal changes in temperature are determined using a finite difference time domain method and a finite difference bio-heat transfer solver that accounts for discrete vessels. Heat transfer from foetus to placenta via the umbilical vein and arteries as well as that across the foetal skin/amniotic fluid/uterine wall boundaries is modelled. Results suggest that for procedures compliant with IEC normal mode conditions (maternal whole-body averaged SAR MWB ≤ 2 W kg -1 (continuous or time-averaged over 6 min)), whole foetal SAR, local foetal SAR 10g and average foetal temperature are within international safety limits. For continuous RF exposure at SAR MWB = 2 W kg -1 over periods of 7.5 min or longer, a maximum local foetal temperature >38 deg. C may occur. However, assessment of the risk posed by such maximum temperatures predicted in a static model is difficult because of frequent foetal movement. Results also confirm that when SAR MWB = 2 W kg -1 , some local SAR 10g values in the mother's trunk and extremities exceed recommended limits.

  9. The Danish national passenger modelModel specification and results

    DEFF Research Database (Denmark)

    Rich, Jeppe; Hansen, Christian Overgaard

    2016-01-01

    , the paper provides a description of a large-scale forecast model with a discussion of the linkage between population synthesis, demand and assignment. Secondly, the paper gives specific attention to model specification and in particular choice of functional form and cost-damping. Specifically we suggest...... a family of logarithmic spline functions and illustrate how it is applied in the model. Thirdly and finally, we evaluate model sensitivity and performance by evaluating the distance distribution and elasticities. In the paper we present results where the spline-function is compared with more traditional...... function types and it is indicated that the spline-function provides a better description of the data. Results are also provided in the form of a back-casting exercise where the model is tested in a back-casting scenario to 2002....

  10. Computer-based procedure for field activities: Results from three evaluations at nuclear power plants

    Energy Technology Data Exchange (ETDEWEB)

    Oxstrand, Johanna [Idaho National Lab. (INL), Idaho Falls, ID (United States); bly, Aaron [Idaho National Lab. (INL), Idaho Falls, ID (United States); LeBlanc, Katya [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2014-09-01

    Nearly all activities that involve human interaction with the systems of a nuclear power plant are guided by procedures. The paper-based procedures (PBPs) currently used by industry have a demonstrated history of ensuring safety; however, improving procedure use could yield tremendous savings in increased efficiency and safety. One potential way to improve procedure-based activities is through the use of computer-based procedures (CBPs). Computer-based procedures provide the opportunity to incorporate context driven job aids, such as drawings, photos, just-in-time training, etc into CBP system. One obvious advantage of this capability is reducing the time spent tracking down the applicable documentation. Additionally, human performance tools can be integrated in the CBP system in such way that helps the worker focus on the task rather than the tools. Some tools can be completely incorporated into the CBP system, such as pre-job briefs, placekeeping, correct component verification, and peer checks. Other tools can be partly integrated in a fashion that reduces the time and labor required, such as concurrent and independent verification. Another benefit of CBPs compared to PBPs is dynamic procedure presentation. PBPs are static documents which limits the degree to which the information presented can be tailored to the task and conditions when the procedure is executed. The CBP system could be configured to display only the relevant steps based on operating mode, plant status, and the task at hand. A dynamic presentation of the procedure (also known as context-sensitive procedures) will guide the user down the path of relevant steps based on the current conditions. This feature will reduce the user’s workload and inherently reduce the risk of incorrectly marking a step as not applicable and the risk of incorrectly performing a step that should be marked as not applicable. As part of the Department of Energy’s (DOE) Light Water Reactors Sustainability Program

  11. Optimization procedures in mammography: First results; Procesos de Optimizacion en Mamografia. Primeros Resultados

    Energy Technology Data Exchange (ETDEWEB)

    Espana Lopez, M. L.; Marcos de Paz, L.; Martin Rincon, C.; Jerez Sainz, I.; Lopez Franco, M. P. [Hospital Universitario de La Princesa. Madrid (Spain)

    2001-07-01

    Optimization procedures in mammography using equipment with a unique target/filter combination can be carried out through such diverse factors as target optical density, technique factors for exposure, screen film combination or processing cycle, in order to obtain an image adequate for the diagnosis with an acceptable risk benefit balance. Diverse studies show an increase in the Standardised Detection Rate of invasive carcinomas with an increase in the optical density among others factors. In our hospital an optimisation process has been established, and as previous step, the target optical density has been increased up to 1,4 DO. The aim of this paper is to value the impact of optical density variation as much in the quality of image as in the entrance surface dose and the average dose to the glandular tissue, comparing them with the results obtained in a previous study. The study has been carried out in a sample of 106 patients, with an average age of 53,4 years, considering 212 clinical images corresponding to the two projections of a same breast with an average compressed thickness of 4,86 cm. An increase of 16,6% on the entrance surface dose and 18% on the average dose to the glandular tissue has been recorded. All the clinical images has been evaluated for the physician as adequate for diagnosis. (Author) 16 refs.

  12. Mid-term results of different aortic valve-sparing procedures in Marfan syndrome.

    Science.gov (United States)

    Schmidtke, Claudia; Karluss, Antje; Sier, Holger; Hüppe, Michael; Brauer, Kirk; Sievers, Hans-H

    2012-03-01

    Marfan patients with aortic root aneurysm are typically treated with the Bentall procedure, though aortic valve-sparing procedures (AVSPs) are also possible. The study aim was to compare the authors' experience with two such techniques performed at their institution, namely a reimplantation according to David (David I) and remodeling according to Yacoub. Between 1996 and 2009, a total of 37 Marfan patients underwent an AVSP at the authors' institution. Of these patients, 25 (mean age 32 +/- 14.9 years) underwent surgery according to David (group D), and 12 (mean age 35 +/- 10.9 years) according to Yacoub (group Y). The patients underwent both clinical and echocardiographic follow up examinations at a mean of 42.0 +/- 36.4 months after surgery. One patient from each group had moved abroad and was lost to follow up. The remaining 35 patients were alive at follow up, and none presented with any major neurological or bleeding complications. In addition, no significant differences were noted between the groups in terms of NYHA classification, left ventricular function, or left ventricular diameter. At follow up, aortic valve function was also comparable between groups, with a peak/mean gradient of 9.4 +/- 6.4/5.3 +/- 3.5 mmHg and 5.1 +/- 3.3/2.8 +/- 1.5 mmHg for groups D and Y, respectively (p = 0.081/0.058). The measured mean grades of aortic valve regurgitation were comparable in groups D and Y (0.6 +/- 0.7 and 1.1 +/- 0.6, respectively; p = 0.055). However, aortic root dimensions obtained via M-mode were smaller in group D patients (29.6 +/- 2.3 mm) than in group Y patients (36.1 +/- 6.6 mm) (p = 0.027). Only three patients from group Y required reoperation on the aortic valve due to valvular regurgitation (p = 0.028); two of these had presented with aortic dissection at the first operation. Both types of AVSP can be performed with comparably good interim clinical results, and also low mortality and morbidity, in patients with Marfan syndrome.

  13. Cochlear Hydrops Analysis Masking Procedure Results in Patients With Unilateral Meniere's Disease

    NARCIS (Netherlands)

    Kingma, Charlotte M.; Wit, Hero P.

    Objective: To investigate the usefulness of the cochlear hydrops analysis masking procedure (CHAMP) as an additional diagnostic test in patients with definite unilateral Meniere's disease. Study Design: Prospective validation study for a diagnostic test. Setting: Tertiary referral center. Patients:

  14. Long-term results of the Latarjet procedure for anterior instability of the shoulder.

    Science.gov (United States)

    Mizuno, Naoko; Denard, Patrick J; Raiss, Patric; Melis, Barbara; Walch, Gilles

    2014-11-01

    The Latarjet procedure is effective in managing anterior glenohumeral instability in the short term, but there is concern for postoperative arthritis. The purpose of this study was to evaluate the long-term functional outcome after the Latarjet procedure and to assess the prevalence of and risk factors for glenohumeral arthritis after this procedure. A retrospective review was conducted of 68 Latarjet procedures at a mean of 20 years postoperatively. The mean age at surgery was 29.4 years. Functional outcome was determined by the Rowe score, subjective shoulder value, and recurrence of instability. Preoperative arthritis and postoperative radiographs were reviewed to evaluate the development or progression of arthritis. The mean Rowe score increased from 37.9 preoperatively to 89.6 at final follow-up (P Latarjet procedure provides excellent long-term outcomes in the treatment of recurrent anterior glenohumeral instability. Twenty years after the Latarjet procedure, arthritis may develop or progress in 23.5% of cases, but the majority of arthritis is mild. Copyright © 2014 Journal of Shoulder and Elbow Surgery Board of Trustees. Published by Elsevier Inc. All rights reserved.

  15. A Comparison of Exposure Control Procedures in CATs Using the 3PL Model

    Science.gov (United States)

    Leroux, Audrey J.; Lopez, Myriam; Hembry, Ian; Dodd, Barbara G.

    2013-01-01

    This study compares the progressive-restricted standard error (PR-SE) exposure control procedure to three commonly used procedures in computerized adaptive testing, the randomesque, Sympson-Hetter (SH), and no exposure control methods. The performance of these four procedures is evaluated using the three-parameter logistic model under the…

  16. Results of the Latarjet coracoid bone block procedure performed by mini invasive approach.

    Science.gov (United States)

    Lateur, Gabriel; Pailhe, Regis; Refaie, Ramsay; Chedal Bornu, Billy Jeremy; Boudissa, Mehdi; Saragaglia, Dominique

    2018-04-10

    The coracoid block technique described by Latarjet was modified by Patte and Walch in order to increase the glenoid surface. Saragaglia further modified this technique and described a minimally invasive approach which allows faster post-operative recovery. The aim of this study was to evaluate the medium-term functional and radiological results of this technique. This is a single surgeon cohort of 40 shoulders in 38 patients (32 men, 6 women) with an average age of 34.5 years operated on between January and December 2014. The skin incision was 3 to 6 cm long allowing the bony block to be passed under the subscapularis tendon without sectioning it and to be placed in lying position. The bone block was fixed with a 6.5 cancellous screw or a 7.0 cannulated screw. At an average follow-up of 48 months, there were no recurrent dislocations. The average WOSI score was 42, the average Constant score was 95 corrected to 97% and the average SSV was 97. Visual analogue scores were 0 at rest and 0.6 with activity. The bone block healed in 92.5% of cases. It was flush with the edge of the glenoid in 84% of cases, lateralised in 10% and medialised in 6% of cases. Mean internal rotation power was 12 kg in the operated shoulder compared with 9 kg in the non-operated shoulder. The treatment of recurrent anterior shoulder instability by mini invasive Latarjet gives excellent medium-term functional results. The rate of recurrent dislocation in this series was zero and internal rotation power was well preserved. This is an excellent alternative to arthroscopic procedures which are yet to demonstrate their superiority over open surgery.

  17. Scale Model Thruster Acoustic Measurement Results

    Science.gov (United States)

    Vargas, Magda; Kenny, R. Jeremy

    2013-01-01

    The Space Launch System (SLS) Scale Model Acoustic Test (SMAT) is a 5% scale representation of the SLS vehicle, mobile launcher, tower, and launch pad trench. The SLS launch propulsion system will be comprised of the Rocket Assisted Take-Off (RATO) motors representing the solid boosters and 4 Gas Hydrogen (GH2) thrusters representing the core engines. The GH2 thrusters were tested in a horizontal configuration in order to characterize their performance. In Phase 1, a single thruster was fired to determine the engine performance parameters necessary for scaling a single engine. A cluster configuration, consisting of the 4 thrusters, was tested in Phase 2 to integrate the system and determine their combined performance. Acoustic and overpressure data was collected during both test phases in order to characterize the system's acoustic performance. The results from the single thruster and 4- thuster system are discussed and compared.

  18. CMS standard model Higgs boson results

    Directory of Open Access Journals (Sweden)

    Garcia-Abia Pablo

    2013-11-01

    Full Text Available In July 2012 CMS announced the discovery of a new boson with properties resembling those of the long-sought Higgs boson. The analysis of the proton-proton collision data recorded by the CMS detector at the LHC, corresponding to integrated luminosities of 5.1 fb−1 at √s = 7 TeV and 19.6 fb−1 at √s = 8 TeV, confirm the Higgs-like nature of the new boson, with a signal strength associated with vector bosons and fermions consistent with the expectations for a standard model (SM Higgs boson, and spin-parity clearly favouring the scalar nature of the new boson. In this note I review the updated results of the CMS experiment.

  19. Thoracoscopic Nuss procedure for young adults with pectus excavatum: excellent midterm results and patient satisfaction.

    Science.gov (United States)

    Hanna, Waël C; Ko, Michael A; Blitz, Maurice; Shargall, Yaron; Compeau, Christopher G

    2013-09-01

    Chest wall remodeling by substernal placement of a Nuss bar is the treatment of choice for children with pectus excavatum; however, it has not yet gained widespread acceptance in adults. We demonstrate that thoracoscopic Nuss bar insertion in young adults is safe and leads to excellent results. Adult patients who underwent thoracoscopic Nuss bar insertion at one institution between 2006 and 2012 were identified. Data on demographics, postoperative outcomes, quality of life, and cosmetic satisfaction was collected. A validated single-step quality of life survey was administered to patients. Student's t test and the Wilcoxon rank sum test were used for statistical analysis. Seventy-three patients (65 male, 8 female) with a median age of 20 years (range, 16 to 51) were included. The median follow-up was 44.6 months (range, 36.9 to 73.26). Most patients (59 of 73, 81%) had one bar placed. The median length of hospital stay was 5 days (range, 3 to 9) and the median duration of epidural anesthesia was 3 days (range, 0 to 7). There were 4 reoperations (5.5%) in the immediate postoperative period: 2 for bar displacement and 2 for poor cosmesis. All reoperations were performed thoracoscopically. Other postoperative complications included pneumothorax (3 of 73, 4.1%) and ileus (1 of 73, 1.3%). Fifty-one patients participated in a quality-of-life survey (73% response rate). The mean self-esteem score improved from 4.6 of 10 preoperatively to 6.5 of 10 postoperatively (p=0.002). The social impact of the pectus deformity became less significant (mean preoperative score 3.6, mean postoperative score 2.8, p=0.02). The severity of initial postoperative pain was much improved on follow-up. The vast majority of patients (41 of 51, 80%) were satisfied with the cosmetic result, and 96% (49 of 51) would opt to have the surgery again. For young adults who wish to correct their pectus deformity, a thoracoscopic Nuss procedure is safe and results in a high rate of patient satisfaction

  20. Comparison of Estimation Procedures for Multilevel AR(1 Models

    Directory of Open Access Journals (Sweden)

    Tanja eKrone

    2016-04-01

    Full Text Available To estimate a time series model for multiple individuals, a multilevel model may be used.In this paper we compare two estimation methods for the autocorrelation in Multilevel AR(1 models, namely Maximum Likelihood Estimation (MLE and Bayesian Markov Chain Monte Carlo.Furthermore, we examine the difference between modeling fixed and random individual parameters.To this end, we perform a simulation study with a fully crossed design, in which we vary the length of the time series (10 or 25, the number of individuals per sample (10 or 25, the mean of the autocorrelation (-0.6 to 0.6 inclusive, in steps of 0.3 and the standard deviation of the autocorrelation (0.25 or 0.40.We found that the random estimators of the population autocorrelation show less bias and higher power, compared to the fixed estimators. As expected, the random estimators profit strongly from a higher number of individuals, while this effect is small for the fixed estimators.The fixed estimators profit slightly more from a higher number of time points than the random estimators.When possible, random estimation is preferred to fixed estimation.The difference between MLE and Bayesian estimation is nearly negligible. The Bayesian estimation shows a smaller bias, but MLE shows a smaller variability (i.e., standard deviation of the parameter estimates.Finally, better results are found for a higher number of individuals and time points, and for a lower individual variability of the autocorrelation. The effect of the size of the autocorrelation differs between outcome measures.

  1. A Proposal for a Procedural Terrain Modelling Framework

    NARCIS (Netherlands)

    Smelik, R.M.; T. Tutenel, T.; Kraker, K.J. de; Bidarra, R.

    2008-01-01

    Manual game content creation is an increasingly laborious task; with each advance in graphics hardware, a higher level of fidelity and detail is achievable and, therefore, expected. Although numerous automatic (e.g. procedural) content generation algorithms and techniques have been developed over

  2. A declarative approach to procedural modeling of virtual worlds

    NARCIS (Netherlands)

    Smelik, R.M.; Tutenel, T.; Kraker, K.J.de; Bidarra, R.

    2011-01-01

    With the ever increasing costs of manual content creation for virtual worlds, the potential of creating it automatically becomes too attractive to ignore. However, for most designers, traditional procedural content generation methods are complex and unintuitive to use, hard to control, and generated

  3. A Survey of Procedural Methods for Terrain Modelling

    NARCIS (Netherlands)

    Smelik, R.M.; Kraker, J.K. de; Groenewegen, S.A.; Tutenel, T.; Bidarra, R.

    2009-01-01

    Procedural methods are a promising but underused alternative to manual content creation. Commonly heard drawbacks are the randomness of and the lack of control over the output and the absence of integrated solutions, although more recent publications increasingly address these issues. This paper

  4. Collaborative CAD Synchronization Based on a Symmetric and Consistent Modeling Procedure

    Directory of Open Access Journals (Sweden)

    Yiqi Wu

    2017-04-01

    Full Text Available One basic issue with collaborative computer aided design (Co-CAD is how to maintain valid and consistent modeling results across all design sites. Moreover, modeling history is important in parametric CAD modeling. Therefore, different from a typical co-editing approach, this paper proposes a novel method for Co-CAD synchronization, in which all Co-CAD sites maintain symmetric and consistent operating procedures. Consequently, the consistency of both modeling results and history can be achieved. In order to generate a valid, unique, and symmetric queue among collaborative sites, a set of correlated mechanisms is presented in this paper. Firstly, the causal relationship of operations is maintained. Secondly, the operation queue is reconstructed for partial concurrency operation, and the concurrent operation can be retrieved. Thirdly, a symmetric, concurrent operation control strategy is proposed to determine the order of operations and resolve possible conflicts. Compared with existing Co-CAD consistency methods, the proposed method is convenient and flexible in supporting collaborative design. The experiment performed based on the collaborative modeling procedure demonstrates the correctness and applicability of this work.

  5. Revisiting Runoff Model Calibration: Airborne Snow Observatory Results Allow Improved Modeling Results

    Science.gov (United States)

    McGurk, B. J.; Painter, T. H.

    2014-12-01

    Deterministic snow accumulation and ablation simulation models are widely used by runoff managers throughout the world to predict runoff quantities and timing. Model fitting is typically based on matching modeled runoff volumes and timing with observed flow time series at a few points in the basin. In recent decades, sparse networks of point measurements of the mountain snowpacks have been available to compare with modeled snowpack, but the comparability of results from a snow sensor or course to model polygons of 5 to 50 sq. km is suspect. However, snowpack extent, depth, and derived snow water equivalent have been produced by the NASA/JPL Airborne Snow Observatory (ASO) mission for spring of 20013 and 2014 in the Tuolumne River basin above Hetch Hetchy Reservoir. These high-resolution snowpack data have exposed the weakness in a model calibration based on runoff alone. The U.S. Geological Survey's Precipitation Runoff Modeling System (PRMS) calibration that was based on 30-years of inflow to Hetch Hetchy produces reasonable inflow results, but modeled spatial snowpack location and water quantity diverged significantly from the weekly measurements made by ASO during the two ablation seasons. The reason is that the PRMS model has many flow paths, storages, and water transfer equations, and a calibrated outflow time series can be right for many wrong reasons. The addition of a detailed knowledge of snow extent and water content constrains the model so that it is a better representation of the actual watershed hydrology. The mechanics of recalibrating PRMS to the ASO measurements will be described, and comparisons in observed versus modeled flow for both a small subbasin and the entire Hetch Hetchy basin will be shown. The recalibrated model provided a bitter fit to the snowmelt recession, a key factor for water managers as they balance declining inflows with demand for power generation and ecosystem releases during the final months of snow melt runoff.

  6. Immersive visualization of dynamic CFD model results

    International Nuclear Information System (INIS)

    Comparato, J.R.; Ringel, K.L.; Heath, D.J.

    2004-01-01

    With immersive visualization the engineer has the means for vividly understanding problem causes and discovering opportunities to improve design. Software can generate an interactive world in which collaborators experience the results of complex mathematical simulations such as computational fluid dynamic (CFD) modeling. Such software, while providing unique benefits over traditional visualization techniques, presents special development challenges. The visualization of large quantities of data interactively requires both significant computational power and shrewd data management. On the computational front, commodity hardware is outperforming large workstations in graphical quality and frame rates. Also, 64-bit commodity computing shows promise in enabling interactive visualization of large datasets. Initial interactive transient visualization methods and examples are presented, as well as development trends in commodity hardware and clustering. Interactive, immersive visualization relies on relevant data being stored in active memory for fast response to user requests. For large or transient datasets, data management becomes a key issue. Techniques for dynamic data loading and data reduction are presented as means to increase visualization performance. (author)

  7. Robust and efficient solution procedures for association models

    DEFF Research Database (Denmark)

    Michelsen, Michael Locht

    2006-01-01

    Equations of state that incorporate the Wertheim association expression are more difficult to apply than conventional pressure explicit equations, because the association term is implicit and requires solution for an internal set of composition variables. In this work, we analyze the convergence ...... behavior of different solution methods and demonstrate how a simple and efficient, yet globally convergent, procedure for the solution of the equation of state can be formulated....

  8. Linkage of PRA models. Phase 1, Results

    Energy Technology Data Exchange (ETDEWEB)

    Smith, C.L.; Knudsen, J.K.; Kelly, D.L.

    1995-12-01

    The goal of the Phase I work of the ``Linkage of PRA Models`` project was to postulate methods of providing guidance for US Nuclear Regulator Commission (NRC) personnel on the selection and usage of probabilistic risk assessment (PRA) models that are best suited to the analysis they are performing. In particular, methods and associated features are provided for (a) the selection of an appropriate PRA model for a particular analysis, (b) complementary evaluation tools for the analysis, and (c) a PRA model cross-referencing method. As part of this work, three areas adjoining ``linking`` analyses to PRA models were investigated: (a) the PRA models that are currently available, (b) the various types of analyses that are performed within the NRC, and (c) the difficulty in trying to provide a ``generic`` classification scheme to groups plants based upon a particular plant attribute.

  9. Engineering Glass Passivation Layers -Model Results

    Energy Technology Data Exchange (ETDEWEB)

    Skorski, Daniel C.; Ryan, Joseph V.; Strachan, Denis M.; Lepry, William C.

    2011-08-08

    The immobilization of radioactive waste into glass waste forms is a baseline process of nuclear waste management not only in the United States, but worldwide. The rate of radionuclide release from these glasses is a critical measure of the quality of the waste form. Over long-term tests and using extrapolations of ancient analogues, it has been shown that well designed glasses exhibit a dissolution rate that quickly decreases to a slow residual rate for the lifetime of the glass. The mechanistic cause of this decreased corrosion rate is a subject of debate, with one of the major theories suggesting that the decrease is caused by the formation of corrosion products in such a manner as to present a diffusion barrier on the surface of the glass. Although there is much evidence of this type of mechanism, there has been no attempt to engineer the effect to maximize the passivating qualities of the corrosion products. This study represents the first attempt to engineer the creation of passivating phases on the surface of glasses. Our approach utilizes interactions between the dissolving glass and elements from the disposal environment to create impermeable capping layers. By drawing from other corrosion studies in areas where passivation layers have been successfully engineered to protect the bulk material, we present here a report on mineral phases that are likely have a morphological tendency to encrust the surface of the glass. Our modeling has focused on using the AFCI glass system in a carbonate, sulfate, and phosphate rich environment. We evaluate the minerals predicted to form to determine the likelihood of the formation of a protective layer on the surface of the glass. We have also modeled individual ions in solutions vs. pH and the addition of aluminum and silicon. These results allow us to understand the pH and ion concentration dependence of mineral formation. We have determined that iron minerals are likely to form a complete incrustation layer and we plan

  10. H12: Examination of safety assessment aims, procedures and results from a wider perspective

    International Nuclear Information System (INIS)

    Neall, F.B; Smith, P.A.

    2004-04-01

    Safety assessment (SA) are a familiar tool for the evaluation of disposal concepts for radioactive waste. There is, however, often confusion in the wider community about the aims, methods and results used in SA. This report aims to present the H12 SA in a way that makes the assessment process clearer and the implications of the results more meaningful both to workers within the SA field and to a wider technical audience. The reasonableness of the assessment results, the quality of the models and databases and redundancy within the natural and engineered barrier system have been considered. A number of recent and somewhat older SAs that address a range of different waste types, host rocks and disposal concepts have been considered, and comparisons made to H12. A further aim is to put both doses and timescales in a more meaningful context. It has been necessary to: consider ways of demonstrating the meaningfulness of calculations that give results for many thousands of years in the future; provide a framework timescale as a context for SA results over long times; demonstrate the smallness of the risk associated with the doses by comparison with other radiological and non-radiological risks. The perception of risk, which is a critical issue for public acceptance of radioactive waste disposal and must be considered when seeking to present safety assessment results 'in perspective' to a wider audience, is also discussed. It is concluded that H12 is comparable in many ways to assessments carried out internationally. Some assumptions are somewhat arbitrary reflecting the generic stage of the Japanese programme, and are likely to become better founded in future exercises. Nevertheless, H12 provides a clear and well-founded message that it is feasible to site and construct a safe repository from HLW in Japan. (author)

  11. Transcatheter aortic valve implantation in bicuspid anatomy: procedural results with two different types of valves.

    Science.gov (United States)

    Presbitero, Patrizia; Iannetta, Loredana; Pagnotta, Paolo; Reimers, Bernhard; Rossi, Marco L; Zavalloni Parenti, Dennis; Bianchi, Giovanni; Bedogni, Francesco

    2018-04-01

    It is well known that bicuspid valve stenosis can be treated with transcatheter aortic valve implantation (TAVI) even if specific issues can cause problems: dilatation of ascending aorta, possible aorthopathy, eccentricity of the valve and calcium distribution in leaflets and in commissures. We classified Bicuspid aortic valve (BAV) in type 0 (2 cusps and no raphe), and type 1 (2 cusps and one or more raphes). The aim of the present study was to report the results of two types of valve (CoreValve from 2009 to 2016 and Lotus valve from 2014 to 2017) in a consecutive series of BAV patients treated in 2 Italian centers. A total of 30 patients with BAV underwent TAVI from September 2009 to March 2017. Mean age was 78±8 years, 54.5% were males and 7.4% had peripheral vasculopathy, 6.5% previous stroke or TIA, 15.6% previous PCI and 9.4% previous coronary artery bypass grafting. Ten patients (30.3%) had a type 1; mean aortic valvular gradient was 57.7±17.7 mmHg; aortic valvular area was 0.7±0.2 mm2, left ventricular ejection fraction was 51.4±10.0% and ascending aorta was 41.0±5.6 mm. Among these 30 patients, 16 of them (group 1) undergone CoreValve implantation and 14 (group 2) undergone Lotus valve implantation. Patients in the first group had a higher Logistic Euroscore (P<0.001) and higher AVA (P=0.026) and valve area CT (P=0.003). Device size in group1 was more often bigger than in group 2 (P<0.001) and postdilatation was never used in the last group. Group 1 had a significant more frequent aortic regurgitation ≥2 assessed with angiography (28.6% vs. 0%; P=0.05). A non-statistically significant higher rate of second valve implantation (6.2% vs. 0%; P=1.00) was also observed. New permanent pacemaker implantation (40.0% vs. 35.7%; P=0.812) was equal in both valves. Postprocedural aortic regurgitation is still an issue in BAV undergone TAVI when: 1) the annulus is big; 2) when we are using self-expandable valves; and 3) in type 0 valves. Lotus valve, with a

  12. A Comparison of Exposure Control Procedures in CAT Systems Based on Different Measurement Models for Testlets

    Science.gov (United States)

    Boyd, Aimee M.; Dodd, Barbara; Fitzpatrick, Steven

    2013-01-01

    This study compared several exposure control procedures for CAT systems based on the three-parameter logistic testlet response theory model (Wang, Bradlow, & Wainer, 2002) and Masters' (1982) partial credit model when applied to a pool consisting entirely of testlets. The exposure control procedures studied were the modified within 0.10 logits…

  13. A testing procedure for wind turbine generators based on the power grid statistical model

    DEFF Research Database (Denmark)

    Farajzadehbibalan, Saber; Ramezani, Mohammad Hossein; Nielsen, Peter

    2017-01-01

    In this study, a comprehensive test procedure is developed to test wind turbine generators with a hardware-in-loop setup. The procedure employs the statistical model of the power grid considering the restrictions of the test facility and system dynamics. Given the model in the latent space, the j...

  14. Modeling and Field Results from Seismic Stimulation

    International Nuclear Information System (INIS)

    Majer, E.; Pride, S.; Lo, W.; Daley, T.; Nakagawa, Seiji; Sposito, Garrison; Roberts, P.

    2006-01-01

    Modeling the effect of seismic stimulation employing Maxwell-Boltzmann theory shows that the important component of stimulation is mechanical rather than fluid pressure effects. Modeling using Biot theory (two phases) shows that the pressure effects diffuse too quickly to be of practical significance. Field data from actual stimulation will be shown to compare to theory

  15. A RENORMALIZATION PROCEDURE FOR TENSOR MODELS AND SCALAR-TENSOR THEORIES OF GRAVITY

    OpenAIRE

    SASAKURA, NAOKI

    2010-01-01

    Tensor models are more-index generalizations of the so-called matrix models, and provide models of quantum gravity with the idea that spaces and general relativity are emergent phenomena. In this paper, a renormalization procedure for the tensor models whose dynamical variable is a totally symmetric real three-tensor is discussed. It is proven that configurations with certain Gaussian forms are the attractors of the three-tensor under the renormalization procedure. Since these Gaussian config...

  16. PROCRU: A model for analyzing crew procedures in approach to landing

    Science.gov (United States)

    Baron, S.; Muralidharan, R.; Lancraft, R.; Zacharias, G.

    1980-01-01

    A model for analyzing crew procedures in approach to landing is developed. The model employs the information processing structure used in the optimal control model and in recent models for monitoring and failure detection. Mechanisms are added to this basic structure to model crew decision making in this multi task environment. Decisions are based on probability assessments and potential mission impact (or gain). Sub models for procedural activities are included. The model distinguishes among external visual, instrument visual, and auditory sources of information. The external visual scene perception models incorporate limitations in obtaining information. The auditory information channel contains a buffer to allow for storage in memory until that information can be processed.

  17. Constitutional Justice Procedure in Lithuania: a Search for Optimal Model

    OpenAIRE

    Pūraitė-Andrikienė, Dovilė

    2017-01-01

    The dissertation systematically analyzes the preconditions for optimising the existing constitutional justice model, i.e. whether the current model meets the expectations of Lithuanian society and the legal community, corresponds to the capabilities of the legal system, and is in line with the tendencies of constitutional justice in European states, identifies the problematic aspects of the existing constitutional justice model and brings forward proposals regarding how the legal regulation c...

  18. A systematic procedure for the incorporation of common cause events into risk and reliability models

    International Nuclear Information System (INIS)

    Fleming, K.N.; Mosleh, A.; Deremer, R.K.

    1986-01-01

    Common cause events are an important class of dependent events with respect to their contribution to system unavailability and to plant risk. Unfortunately, these events have not been treated with any king of consistency in applied risk studies over the past decade. Many probabilistic risk assessments (PRA) have not included these events at all, and those that have did not employ the kind of systematic procedures that are needed to achieve consistency, accuracy, and credibility in this area of PRA methodology. In this paper, the authors report on the progress recently made in the development of a systematic approach for incorporating common cause events into applied risk and reliability evaluations. This approach takes advantage of experience from recently completed PRAs and is the result of a project, sponsored by the Electric Power Research Institute (EPRI), in which procedures for dependent events analysis are being developed. Described in this paper is a general framework for system-level common cause failure (CCF) analysis and its application to a three-train auxiliary feedwater system. Within this general framework, three parametric CCF models are compared, including the basic parameter (BP), multiple Greek letter (MGL), and binominal failure rate (BFR) models. Pitfalls of not following the recommended procedure are discussed, and some old issues, such as the benefits of redundancy and diversity, are reexamined. (orig.)

  19. Coupled Michigan MHD - Rice Convection Model Results

    Science.gov (United States)

    de Zeeuw, D.; Sazykin, S.; Wolf, D.; Gombosi, T.; Powell, K.

    2002-12-01

    A new high performance Rice Convection Model (RCM) has been coupled to the adaptive-grid Michigan MHD model (BATSRUS). This fully coupled code allows us to self-consistently simulate the physics in the inner and middle magnetosphere. A study will be presented of the basic characteristics of the inner and middle magnetosphere in the context of a single coupled-code run for idealized storm inputs. The analysis will include region-2 currents, shielding of the inner magnetosphere, partial ring currents, pressure distribution, magnetic field inflation, and distribution of pV^gamma.

  20. modelling room cooling capacity with fuzzy logic procedure

    African Journals Online (AJOL)

    user

    for automatic and economical supplementary tools that will allow expertise input into design process [9]. Reasoning based on fuzzy models was however identified to provide an optional direction of handling the way humans think and make judgments [10]. This study developed and validated a model capable of estimating ...

  1. modelling room cooling capacity with fuzzy logic procedure

    African Journals Online (AJOL)

    The primary aim of this study is to develop a model for estimation of the cooling requirement of residential rooms. Fuzzy logic was employed to model four input variables (window area (m2), roof area (m2), external wall area (m2) and internal load (Watt). The algorithm of the inference engine applied sets of 81 linguistic ...

  2. Radial artery spasm associated with transradial cardiovascular procedures: results from the RAS registry.

    Science.gov (United States)

    Goldsmit, Alejandro; Kiemeneij, Ferdinand; Gilchrist, Ian C; Kantor, Pablo; Kedev, Sasko; Kwan, Tak; Dharma, Surya; Valdivieso, Leon; Wenstemberg, Bernard; Patel, Tejas

    2014-01-01

    To report the incidence and predictors of moderate/severe radial artery spasm (RAS) in patients undergoing cardiovascular percutaneous procedures through a transradial approach (TRA) in centers with TRA expertise. Data regarding the actual rate of clinically meaningful RAS are limited due to difference in study designs and operator expertise. The RAS registry, an international (14 centers from Argentina, Chile, India, Indonesia, Macedonia, The Netherlands and United States of America) registry that included 1,868 patients undergoing TRA cardiovascular procedures (63.5% diagnostic and 56.5% therapeutic).All selected centers used TRA as default strategy in the cardiac catheterization laboratory. Throughout 2012, each center included all consecutive TRA cases (during a 2-month period) into a dedicated database covering clinical characteristics as well as procedural topics related to TRA patterns and RAS occurrence. The incidence of moderate/severe RAS was 2.7%. Only 0.7% of patients required crossover (8 to transfemoral and 5 to contralateral TRA). Patients with moderately/severe spasm were more frequently females, had a history of dyslipidemia, received more often a 7F sheath and more puncture attempts than patients without spasm. By multivariate analysis, the need for more than one attempt and the use of a 7 F sheath were independent predictors of the development of moderate/severe RAS. The incidence of moderate/severe RAS is low in centers with a default TRA. Its development appears to be strongly related to the numbers of puncture attempts and the use of large sheaths. Copyright © 2013 Wiley Periodicals, Inc.

  3. Graphical interpretation of numerical model results

    International Nuclear Information System (INIS)

    Drewes, D.R.

    1979-01-01

    Computer software has been developed to produce high quality graphical displays of data from a numerical grid model. The code uses an existing graphical display package (DISSPLA) and overcomes some of the problems of both line-printer output and traditional graphics. The software has been designed to be flexible enough to handle arbitrarily placed computation grids and a variety of display requirements

  4. Using X-ray computed tomography to evaluate the initial saturation resulting from different saturation procedures

    DEFF Research Database (Denmark)

    Christensen, Britt Stenhøj Baun; Wildenschild, D; Jensen, K.H.

    2006-01-01

    saturation. In this study three techniques often applied in the laboratory have been evaluated for a fine sand sample: (1) venting of the sample with carbon dioxide prior to saturation, (2) applying vacuum to the sample in the beginning of the saturation procedure, and finally (3) the use of degassed water...... for saturation. Evaluation of the different enhanced saturation techniques was done with Xray computed tomography (CT) and gravimetrically. The use of CT scanning makes it possible to observe the spatial distribution of wetting and non-wetting phases in the porous medium in a non-destructive way. In this case...

  5. Combination procedure for the precise determination of Z boson parameters from results of the LEP experiments

    CERN Document Server

    CERN. Geneva

    2001-01-01

    The precise determination of the Z boson parameters from the measurements at the Z resonance by the four collaborations ALEPH, DELPHI, L3 and OPAL in e+e- collisions at the large electron positron collider LEP at CERN is a landmark for precision tests of the electroweak theory. The four experiments measured quantities which were used to extract the mass and width of the Z boson, the hadronic cross-section at the pole of the resonance, the ratio of hadronic and leptonic decay widths, and the leptonic forward-backward asymmetries at the pole. The combination procedure based on these parameters is presented in this paper.

  6. Computer-Based Procedures for Field Workers in Nuclear Power Plants: Development of a Model of Procedure Usage and Identification of Requirements

    Energy Technology Data Exchange (ETDEWEB)

    Katya Le Blanc; Johanna Oxstrand

    2012-04-01

    The nuclear industry is constantly trying to find ways to decrease the human error rate, especially the human errors associated with procedure use. As a step toward the goal of improving procedure use performance, researchers, together with the nuclear industry, have been looking at replacing the current paper-based procedures with computer-based procedure systems. The concept of computer-based procedures is not new by any means; however most research has focused on procedures used in the main control room. Procedures reviewed in these efforts are mainly emergency operating procedures and normal operating procedures. Based on lessons learned for these previous efforts we are now exploring a more unknown application for computer based procedures - field procedures, i.e. procedures used by nuclear equipment operators and maintenance technicians. The Idaho National Laboratory and participants from the U.S. commercial nuclear industry are collaborating in an applied research effort with the objective of developing requirements and specifications for a computer-based procedure system to be used by field workers. The goal is to identify the types of human errors that can be mitigated by using computer-based procedures and how to best design the computer-based procedures to do so. This paper describes the development of a Model of Procedure Use and the qualitative study on which the model is based. The study was conducted in collaboration with four nuclear utilities and five research institutes. During the qualitative study and the model development requirements and for computer-based procedures were identified.

  7. Hybrid procedures for complex thoracoabdominal aortic aneurysms: early results and secondary interventions.

    Science.gov (United States)

    Muehling, Bernd M; Bischoff, G; Schelzig, H; Sunder-Plassmann, L; Orend, K H

    2010-02-01

    Hybrid procedures for thoracoabdominal aortic aneurysms (TAAA) have been previously described as an attractive alternative to open reconstruction. Between 1999 and 2009, 16 patients with a median age of 67years underwent hybrid repair of a TAAA (Crawford type I: 3, type II: 3, type III: 1, and type IV: 9). In 94%, 3 and more severe comorbidities were present, with previous aortic surgery in 56% of the patients; elective/urgent repair was done in 10 and emergent surgery in 6 patients. Primary technical success was 100%, with 31 vessels grafted. Elective/urgent mortality was 20% (2 of 10) and emergent mortality 50% (3 of 6). During follow-up time (median: 12 months) 2 patients died and 2 patients had to undergo secondary interventions. In high-risk patients especially after prior aortic surgery hybrid repair of TAAA is feasible. However, due to high mortality rates especially in the emergent situation this procedure should be reserved only for decidedly selected patients.

  8. Graded changes in enamel component volumes resulted from a short tooth bleaching procedure.

    Science.gov (United States)

    Ferreira, Artemisa Fernanda Moura; Perez, Flávia Maria de Moraes Ramos; Limeira Júnior, Francisco de Assis; de Moura, Mirella de Fátima Liberato; de Sousa, Frederico Barbosa

    2016-05-01

    To test the hypothesis that changes in enamel component volumes (mineral, organic, and water volumes, and permeability) are graded from outer to inner enamel after a short bleaching procedure. Extracted unerupted human third molars had half of their crowns bleached (single bleaching session, 3 × 15 min), and tooth shade changes in bleached parts were analyzed with a spectrophotometer. Ground sections were prepared, component volumes and permeability were quantified at histological points located at varying distances from the enamel surface (n=10 points/location), representing conditions before and after bleaching. Tooth shade changes were significant (pvolume (in decreasing order of relevance: mineral loss, organic gain, water gain, and decrease in permeability) with the set of distances from the enamel surface (graded from the enamel surface inward) (canonical R(2)=0.97; p99%). Changes in enamel composition after a short bleaching procedure followed a gradient within component volumes (mineral loss>organic gain>water gain>decrease in permeability) and decreased from the enamel surface inward. Copyright © 2016 Elsevier Ltd. All rights reserved.

  9. Ignalina NPP Safety Analysis: Models and Results

    International Nuclear Information System (INIS)

    Uspuras, E.

    1999-01-01

    Research directions, linked to safety assessment of the Ignalina NPP, of the scientific safety analysis group are presented: Thermal-hydraulic analysis of accidents and operational transients; Thermal-hydraulic assessment of Ignalina NPP Accident Localization System and other compartments; Structural analysis of plant components, piping and other parts of Main Circulation Circuit; Assessment of RBMK-1500 reactor core and other. Models and main works carried out last year are described. (author)

  10. Procedures and models for estimating preconstruction costs of highway projects.

    Science.gov (United States)

    2012-07-01

    This study presents data driven and component based PE cost prediction models by utilizing critical factors retrieved from ten years of historical project data obtained from ODOT roadway division. The study used factor analysis of covariance and corr...

  11. Modeling clicks beyond the first result page

    NARCIS (Netherlands)

    Chuklin, A.; Serdyukov, P.; de Rijke, M.

    2013-01-01

    Most modern web search engines yield a list of documents of a fixed length (usually 10) in response to a user query. The next ten search results are usually available in one click. These documents either replace the current result page or are appended to the end. Hence, in order to examine more

  12. A Bidirectional Coupling Procedure Applied to Multiscale Respiratory Modeling

    Energy Technology Data Exchange (ETDEWEB)

    Kuprat, Andrew P.; Kabilan, Senthil; Carson, James P.; Corley, Richard A.; Einstein, Daniel R.

    2013-07-01

    In this study, we present a novel multiscale computational framework for efficiently linking multiple lower-dimensional models describing the distal lung mechanics to imaging-based 3D computational fluid dynamics (CFD) models of the upper pulmonary airways in order to incorporate physiologically appropriate outlet boundary conditions. The framework is an extension of the Modified Newton’s Method with nonlinear Krylov accelerator developed by Carlson and Miller [1, 2, 3]. Our extensions include the retention of subspace information over multiple timesteps, and a special correction at the end of a timestep that allows for corrections to be accepted with verified low residual with as little as a single residual evaluation per timestep on average. In the case of a single residual evaluation per timestep, the method has zero additional computational cost compared to uncoupled or unidirectionally coupled simulations. We expect these enhancements to be generally applicable to other multiscale coupling applications where timestepping occurs. In addition we have developed a “pressure-drop” residual which allows for stable coupling of flows between a 3D incompressible CFD application and another (lower-dimensional) fluid system. We expect this residual to also be useful for coupling non-respiratory incompressible fluid applications, such as multiscale simulations involving blood flow. The lower-dimensional models that are considered in this study are sets of simple ordinary differential equations (ODEs) representing the compliant mechanics of symmetric human pulmonary airway trees. To validate the method, we compare the predictions of hybrid CFD-ODE models against an ODE-only model of pulmonary airflow in an idealized geometry. Subsequently, we couple multiple sets of ODEs describing the distal lung to an imaging-based human lung geometry. Boundary conditions in these models consist of atmospheric pressure at the mouth and intrapleural pressure applied to the multiple

  13. A bidirectional coupling procedure applied to multiscale respiratory modeling

    Energy Technology Data Exchange (ETDEWEB)

    Kuprat, A.P., E-mail: andrew.kuprat@pnnl.gov [Fundamental and Computational Sciences Directorate, Pacific Northwest National Laboratory, Richland, WA (United States); Kabilan, S., E-mail: senthil.kabilan@pnnl.gov [Fundamental and Computational Sciences Directorate, Pacific Northwest National Laboratory, Richland, WA (United States); Carson, J.P., E-mail: james.carson@pnnl.gov [Fundamental and Computational Sciences Directorate, Pacific Northwest National Laboratory, Richland, WA (United States); Corley, R.A., E-mail: rick.corley@pnnl.gov [Fundamental and Computational Sciences Directorate, Pacific Northwest National Laboratory, Richland, WA (United States); Einstein, D.R., E-mail: daniel.einstein@pnnl.gov [Fundamental and Computational Sciences Directorate, Pacific Northwest National Laboratory, Richland, WA (United States)

    2013-07-01

    In this study, we present a novel multiscale computational framework for efficiently linking multiple lower-dimensional models describing the distal lung mechanics to imaging-based 3D computational fluid dynamics (CFDs) models of the upper pulmonary airways in order to incorporate physiologically appropriate outlet boundary conditions. The framework is an extension of the modified Newton’s method with nonlinear Krylov accelerator developed by Carlson and Miller [1], Miller [2] and Scott and Fenves [3]. Our extensions include the retention of subspace information over multiple timesteps, and a special correction at the end of a timestep that allows for corrections to be accepted with verified low residual with as little as a single residual evaluation per timestep on average. In the case of a single residual evaluation per timestep, the method has zero additional computational cost compared to uncoupled or unidirectionally coupled simulations. We expect these enhancements to be generally applicable to other multiscale coupling applications where timestepping occurs. In addition we have developed a “pressure-drop” residual which allows for stable coupling of flows between a 3D incompressible CFD application and another (lower-dimensional) fluid system. We expect this residual to also be useful for coupling non-respiratory incompressible fluid applications, such as multiscale simulations involving blood flow. The lower-dimensional models that are considered in this study are sets of simple ordinary differential equations (ODEs) representing the compliant mechanics of symmetric human pulmonary airway trees. To validate the method, we compare the predictions of hybrid CFD–ODE models against an ODE-only model of pulmonary airflow in an idealized geometry. Subsequently, we couple multiple sets of ODEs describing the distal lung to an imaging-based human lung geometry. Boundary conditions in these models consist of atmospheric pressure at the mouth and intrapleural

  14. A bidirectional coupling procedure applied to multiscale respiratory modeling

    International Nuclear Information System (INIS)

    Kuprat, A.P.; Kabilan, S.; Carson, J.P.; Corley, R.A.; Einstein, D.R.

    2013-01-01

    In this study, we present a novel multiscale computational framework for efficiently linking multiple lower-dimensional models describing the distal lung mechanics to imaging-based 3D computational fluid dynamics (CFDs) models of the upper pulmonary airways in order to incorporate physiologically appropriate outlet boundary conditions. The framework is an extension of the modified Newton’s method with nonlinear Krylov accelerator developed by Carlson and Miller [1], Miller [2] and Scott and Fenves [3]. Our extensions include the retention of subspace information over multiple timesteps, and a special correction at the end of a timestep that allows for corrections to be accepted with verified low residual with as little as a single residual evaluation per timestep on average. In the case of a single residual evaluation per timestep, the method has zero additional computational cost compared to uncoupled or unidirectionally coupled simulations. We expect these enhancements to be generally applicable to other multiscale coupling applications where timestepping occurs. In addition we have developed a “pressure-drop” residual which allows for stable coupling of flows between a 3D incompressible CFD application and another (lower-dimensional) fluid system. We expect this residual to also be useful for coupling non-respiratory incompressible fluid applications, such as multiscale simulations involving blood flow. The lower-dimensional models that are considered in this study are sets of simple ordinary differential equations (ODEs) representing the compliant mechanics of symmetric human pulmonary airway trees. To validate the method, we compare the predictions of hybrid CFD–ODE models against an ODE-only model of pulmonary airflow in an idealized geometry. Subsequently, we couple multiple sets of ODEs describing the distal lung to an imaging-based human lung geometry. Boundary conditions in these models consist of atmospheric pressure at the mouth and intrapleural

  15. A single-photon ecat reconstruction procedure based on a PSF model

    International Nuclear Information System (INIS)

    Ying-Lie, O.

    1984-01-01

    Emission Computed Axial Tomography (ECAT) has been applied in nuclear medicine for the past few years. Owing to attenuation and scatter along the ray path, adequate correction methods are required. In this thesis, a correction method for attenuation, detector response and Compton scatter has been proposed. The method developed is based on a PSF model. The parameters of the models were derived by fitting experimental and simulation data. Because of its flexibility, a Monte Carlo simulation method has been employed. Using the PSF models, it was found that the ECAT problem can be described by the added modified equation. Application of the reconstruction procedure on simulation data yield satisfactory results. The algorithm tends to amplify noise and distortion in the data, however. Therefore, the applicability of the method on patient studies remain to be seen. (Auth.)

  16. [The emphases and basic procedures of genetic counseling in psychotherapeutic model].

    Science.gov (United States)

    Zhang, Yuan-Zhi; Zhong, Nanbert

    2006-11-01

    The emphases and basic procedures of genetic counseling are all different with those in old models. In the psychotherapeutic model, genetic counseling will not only focus on counselees' genetic disorders and birth defects, but also their psychological problems. "Client-centered therapy" termed by Carl Rogers plays an important role in genetic counseling process. The basic procedures of psychotherapeutic model of genetic counseling include 7 steps: initial contact, introduction, agendas, inquiry of family history, presenting information, closing the session and follow-up.

  17. Comparison of In-Flight Measured and Computed Aeroelastic Damping: Modal Identification Procedures and Modeling Approaches

    Directory of Open Access Journals (Sweden)

    Roberto da Cunha Follador

    2016-04-01

    Full Text Available The Operational Modal Analysis technique is a methodology very often applied for the identification of dynamic systems when the input signal is unknown. The applied methodology is based on a technique to estimate the Frequency Response Functions and extract the modal parameters using only the structural dynamic response data, without assuming the knowledge of the excitation forces. Such approach is an adequate way for measuring the aircraft aeroelastic response due to random input, like atmospheric turbulence. The in-flight structural response has been measured by accelerometers distributed along the aircraft wings, fuselage and empennages. The Enhanced Frequency Domain Decomposition technique was chosen to identify the airframe dynamic parameters. This technique is based on the hypothesis that the system is randomly excited with a broadband spectrum with almost constant power spectral density. The system identification procedure is based on the Single Value Decomposition of the power spectral densities of system output signals, estimated by the usual Fast Fourier Transform method. This procedure has been applied to different flight conditions to evaluate the modal parameters and the aeroelastic stability trends of the airframe under investigation. The experimental results obtained by this methodology were compared with the predicted results supplied by aeroelastic numerical models in order to check the consistency of the proposed output-only methodology. The objective of this paper is to compare in-flight measured aeroelastic damping against the corresponding parameters computed from numerical aeroelastic models. Different aerodynamic modeling approaches should be investigated such as the use of source panel body models, cruciform and flat plate projection. As a result of this investigation it is expected the choice of the better aeroelastic modeling and Operational Modal Analysis techniques to be included in a standard aeroelastic

  18. Fracture mapping in the ventilation drift at Stripa: procedures and results

    International Nuclear Information System (INIS)

    Rouleau, A.; Gale, J.E.; Baleshta, J.

    1981-03-01

    Detail maps of the fracture system in the ventilation drift at the Stripa mine have been prepared. The procedures used in preparing the maps of the floor and walls of the ventilation drift are documented in this report. The fracture data presented in the detailed maps are heavily supplemented by a coded data file. Each discrete fracture, vein, or fracture zone has been identified by a number on the map and this number has been used to link the map to the data file. This approach permits maximum use of the fracture data by other researchers interpreting completed and on-going experiments or as an aid in planning and interpreting future experiments. 9 refs., 7 figs., 2 tabs

  19. Computational model for dosimetric purposes in dental procedures

    International Nuclear Information System (INIS)

    Kawamoto, Renato H.; Campos, Tarcisio R.

    2013-01-01

    This study aims to develop a computational model for dosimetric purposes the oral region, based on computational tools SISCODES and MCNP-5, to predict deterministic effects and minimize stochastic effects caused by ionizing radiation by radiodiagnosis. Based on a set of digital information provided by computed tomography, three-dimensional voxel model was created, and its tissues represented. The model was exported to the MCNP code. In association with SICODES, we used the Monte Carlo N-Particle Transport Code (MCNP-5) method to play the corresponding interaction of nuclear particles with human tissues statistical process. The study will serve as a source of data for dosimetric studies in the oral region, providing deterministic effect and minimize the stochastic effect of ionizing radiation

  20. Complications after Surgical Procedures in Patients with Cardiac Implantable Electronic Devices: Results of a Prospective Registry.

    Science.gov (United States)

    Silva, Katia Regina da; Albertini, Caio Marcos de Moraes; Crevelari, Elizabeth Sartori; Carvalho, Eduardo Infante Januzzi de; Fiorelli, Alfredo Inácio; Martinelli, Martino; Costa, Roberto

    2016-09-01

    Complications after surgical procedures in patients with cardiac implantable electronic devices (CIED) are an emerging problem due to an increasing number of such procedures and aging of the population, which consequently increases the frequency of comorbidities. To identify the rates of postoperative complications, mortality, and hospital readmissions, and evaluate the risk factors for the occurrence of these events. Prospective and unicentric study that included all individuals undergoing CIED surgical procedures from February to August 2011. The patients were distributed by type of procedure into the following groups: initial implantations (cohort 1), generator exchange (cohort 2), and lead-related procedures (cohort 3). The outcomes were evaluated by an independent committee. Univariate and multivariate analyses assessed the risk factors, and the Kaplan-Meier method was used for survival analysis. A total of 713 patients were included in the study and distributed as follows: 333 in cohort 1, 304 in cohort 2, and 76 in cohort 3. Postoperative complications were detected in 7.5%, 1.6%, and 11.8% of the patients in cohorts 1, 2, and 3, respectively (p = 0.014). During a 6-month follow-up, there were 58 (8.1%) deaths and 75 (10.5%) hospital readmissions. Predictors of hospital readmission included the use of implantable cardioverter-defibrillators (odds ratio [OR] = 4.2), functional class III--IV (OR = 1.8), and warfarin administration (OR = 1.9). Predictors of mortality included age over 80 years (OR = 2.4), ventricular dysfunction (OR = 2.2), functional class III-IV (OR = 3.3), and warfarin administration (OR = 2.3). Postoperative complications, hospital readmissions, and deaths occurred frequently and were strongly related to the type of procedure performed, type of CIED, and severity of the patient's underlying heart disease. Complicações após procedimentos cirúrgicos em portadores de dispositivos cardíacos eletrônicos implantáveis (DCEI) são um

  1. EFFECT OF LOCATION AND BONE GRAFT REMODELING ON RESULTS OF BRISTOW-LATARJET PROCEDURE

    Directory of Open Access Journals (Sweden)

    D. A. Malanin

    2016-01-01

    Full Text Available Introduction. Operation Bristow-Latarjet proved itself as one of the most effective and predictable surgical treatments. despite its widespread use, there are various complications associated with improper installation of the bone block and the violation of its remodeling.Objective: To obtain new data on the effect of location and remodeling of bone graft block on functional outcome and stability of the shoulder joint in patients with recurrent anterior instability after the operation Bristow-latarjet.Material and methods. The material for the study served as the analysis of results of treatment of 64 patients with posttraumatic recurrent anterior shoulder dislocation who underwent Bristow-latarjet operation. postoperatively, assessed a provision and the degree of bone remodeling unit according to computed tomography in the sagittal, axial slices, and through 3d modeling. To evaluate the functional outcome scale were used western Ontario Shoulder Index (wOSI and Rowe scale.Results. At the level of the articular surface (congruent or flattening in the axial plane were 89% bone blocks, too medially or laterally arranged 9% and 2% grafts, respectively. On sagittal cT images in the middle third of the articular surface of the scapula was located 28% of the bone blocks at the bottom 60%, in the upper third of 12%. Analysis of the dependence of the results of treatment of graft positioning showed that patients with excellent and good summary on the scale WOSI and Rowe, had a correct location of the bone block in the middle and lower third of the articular process of the blade. It can be assumed that excessive lateralized or medialized bone block position in the axial plane of a more profound effect on the outcome than cranial displacement of the latter with the sagittal plane. Bony union of the graft was found by CT in 74% of cases, soft tissue 26%, the degree of resorption of the graft revealed 0-1 84% 2-3 degree in 26% of cases. In the last periods

  2. Microplasticity of MMC. Experimental results and modelling

    Energy Technology Data Exchange (ETDEWEB)

    Maire, E. (Groupe d' Etude de Metallurgie Physique et de Physique des Materiaux, INSA, 69 Villeurbanne (France)); Lormand, G. (Groupe d' Etude de Metallurgie Physique et de Physique des Materiaux, INSA, 69 Villeurbanne (France)); Gobin, P.F. (Groupe d' Etude de Metallurgie Physique et de Physique des Materiaux, INSA, 69 Villeurbanne (France)); Fougeres, R. (Groupe d' Etude de Metallurgie Physique et de Physique des Materiaux, INSA, 69 Villeurbanne (France))

    1993-11-01

    The microplastic behavior of several MMC is investigated by means of tension and compression tests. This behavior is assymetric : the proportional limit is higher in tension than in compression but the work hardening rate is higher in compression. These differences are analysed in terms of maxium of the Tresca's shear stress at the interface (proportional limit) and of the emission of dislocation loops during the cooling (work hardening rate). On another hand, a model is proposed to calculate the value of the yield stress, describing the composite as a material composed of three phases : inclusion, unaffected matrix and matrix surrounding the inclusion having a gradient in the density of the thermally induced dilocations. (orig.).

  3. An auto-calibration procedure for empirical solar radiation models

    NARCIS (Netherlands)

    Bojanowski, J.S.; Donatelli, Marcello; Skidmore, A.K.; Vrieling, A.

    2013-01-01

    Solar radiation data are an important input for estimating evapotranspiration and modelling crop growth. Direct measurement of solar radiation is now carried out in most European countries, but the network of measuring stations is too sparse for reliable interpolation of measured values. Instead of

  4. Constructing Self-Modeling Videos: Procedures and Technology

    Science.gov (United States)

    Collier-Meek, Melissa A.; Fallon, Lindsay M.; Johnson, Austin H.; Sanetti, Lisa M. H.; Delcampo, Marisa A.

    2012-01-01

    Although widely recommended, evidence-based interventions are not regularly utilized by school practitioners. Video self-modeling is an effective and efficient evidence-based intervention for a variety of student problem behaviors. However, like many other evidence-based interventions, it is not frequently used in schools. As video creation…

  5. TSCALE: A New Multidimensional Scaling Procedure Based on Tversky's Contrast Model.

    Science.gov (United States)

    DeSarbo, Wayne S.; And Others

    1992-01-01

    TSCALE, a multidimensional scaling procedure based on the contrast model of A. Tversky for asymmetric three-way, two-mode proximity data, is presented. TSCALE conceptualizes a latent dimensional structure to describe the judgmental stimuli. A Monte Carlo analysis and two consumer psychology applications illustrate the procedure. (SLD)

  6. A single model procedure for estimating tank calibration equations

    International Nuclear Information System (INIS)

    Liebetrau, A.M.

    1997-10-01

    A fundamental component of any accountability system for nuclear materials is a tank calibration equation that relates the height of liquid in a tank to its volume. Tank volume calibration equations are typically determined from pairs of height and volume measurements taken in a series of calibration runs. After raw calibration data are standardized to a fixed set of reference conditions, the calibration equation is typically fit by dividing the data into several segments--corresponding to regions in the tank--and independently fitting the data for each segment. The estimates obtained for individual segments must then be combined to obtain an estimate of the entire calibration function. This process is tedious and time-consuming. Moreover, uncertainty estimates may be misleading because it is difficult to properly model run-to-run variability and between-segment correlation. In this paper, the authors describe a model whose parameters can be estimated simultaneously for all segments of the calibration data, thereby eliminating the need for segment-by-segment estimation. The essence of the proposed model is to define a suitable polynomial to fit to each segment and then extend its definition to the domain of the entire calibration function, so that it (the entire calibration function) can be expressed as the sum of these extended polynomials. The model provides defensible estimates of between-run variability and yields a proper treatment of between-segment correlations. A portable software package, called TANCS, has been developed to facilitate the acquisition, standardization, and analysis of tank calibration data. The TANCS package was used for the calculations in an example presented to illustrate the unified modeling approach described in this paper. With TANCS, a trial calibration function can be estimated and evaluated in a matter of minutes

  7. Activities of radiopharmaceuticals administered for diagnostic and therapeutic procedures in nuclear medicine in Argentina: results of a national survey

    International Nuclear Information System (INIS)

    Bomben, Ana M.; Chiliutti, Claudia A.

    2004-01-01

    Nuclear medicine in Argentine is carried out at 292 centres, distributed all over the country, mainly concentrated in the capital cities of the provinces. With the purpose of knowing the activity levels of radiopharmaceuticals that were administered to patients for diagnostic and therapeutic procedures in nuclear medicine, a national survey was conducted, during 2001 and 2002. This survey was answered voluntarily by 107 centres. Sixty-four percent of the participants centres are equipped with SPECT system while the other centres have a gamma camera or scintiscanner. There were 37 nuclear medicine procedures, chosen among those most frequently performed, were included in the survey. In those diagnostic procedures were included tests for: bone, brain, thyroid, kidney, liver, lung and cardiovascular system; and also activities administered for some therapeutic procedures. The nuclear medicine physicians reported the different radiopharmaceutical activities administered to typical adult patients. In this paper are presented the average radiopharmaceutical activity administered for each of the diagnostic and therapeutic procedures included in the survey and the range and distribution of values. In order to place these data in a frame of reference, these average values were compared to the guidance levels for diagnostic procedures in nuclear medicine mentioned at the Safety Series no. 115. From this comparison it was noticed that the activities administered in the 40% of the diagnostic procedures included in the survey were between ±30% of the reference values. For those nuclear medicine procedures that could not be compared with the above mentioned guidance levels, the comparison was made with values published by UNSCEAR or standards recommended by international bodies. As a result of this study, it is important to point out the need to continue the gathering of data in a wider scale survey to increase the knowledge about national trends. It is also essential to widely

  8. Generation of normative pediatric skull models for use in cranial vault remodeling procedures.

    Science.gov (United States)

    Saber, Nikoo R; Phillips, John; Looi, Thomas; Usmani, Zoha; Burge, Jonathan; Drake, James; Kim, Peter C W

    2012-03-01

    While the goal of craniofacial reconstruction surgery is to restore the cranial head shape as much towards normal as possible, for the individual patient, there is, in fact, no normal three-dimensional (3D) model to act as a guide. In this project, we generated a library of normative pediatric skulls from which a guiding template could be fabricated for a more standardized, objective and precise correction of craniosynostosis. Computed tomography data from 103 normal subjects aged 8-12 months were compiled and a 3D computational model of the skull was generated for each subject. The models were mathematically registered to a baseline model for each month of age within this range and then averaged, resulting in a single 3D point cloud. An external cranial surface was subsequently passed through the point cloud and its shape and size customized to fit the head circumference of individual patients. The resultant fabricated skull models provide a novel and applicable tool for a detailed, quantitative comparison between the normative and patient skulls for preoperative planning and practice for a variety of craniofacial procedures including vault remodeling. Additionally, it was possible to extract the suprafrontal orbit anatomy from the normative model and fabricate a bandeau template to guide intraoperative reshaping. Normative head shapes for pediatric patients have wide application for craniofacial surgery including planning, practice, standarized operative repair, and standardized measurement and reporting of outcomes.

  9. A Computational Model of the Temporal Dynamics of Plasticity in Procedural Learning: Sensitivity to Feedback Timing

    Directory of Open Access Journals (Sweden)

    Vivian V. Valentin

    2014-07-01

    Full Text Available The evidence is now good that different memory systems mediate the learning of different types of category structures. In particular, declarative memory dominates rule-based (RB category learning and procedural memory dominates information-integration (II category learning. For example, several studies have reported that feedback timing is critical for II category learning, but not for RB category learning – results that have broad support within the memory systems literature. Specifically, II category learning has been shown to be best with feedback delays of 500ms compared to delays of 0 and 1000ms, and highly impaired with delays of 2.5 seconds or longer. In contrast, RB learning is unaffected by any feedback delay up to 10 seconds. We propose a neurobiologically detailed theory of procedural learning that is sensitive to different feedback delays. The theory assumes that procedural learning is mediated by plasticity at cortical-striatal synapses that are modified by dopamine-mediated reinforcement learning. The model captures the time-course of the biochemical events in the striatum that cause synaptic plasticity, and thereby accounts for the empirical effects of various feedback delays on II category learning.

  10. Development of procedures to stabilize chlorfenvinphos in model cattle dips

    Energy Technology Data Exchange (ETDEWEB)

    Caceres, Tanya [Pontificia Universidad Catolica del Ecuador, Quito (Ecuador). Dept. de Biologia; University of South Australia (Australia). Centre for Environmental Risk Assessment and Remediation (CERAR); E-mail: cactp001@students.unisa.edu.au; Pastor, Yolanda; Merino, Ramiro [Comision Ecuatoriana de Energia Atomica, Quito (Ecuador). Dept. de Ecotoxicologia

    2007-07-01

    The environmental fate and dissipation of the acaricide chlorfenvinphos was studied in water and sediment in model cattle dips with monthly recharge and without monthly recharge. Chlorfenvinphos concentration decreased with time in both model dips and the monthly recharge at 10% of the initial concentration was inefficient to maintain the right concentration which would be effective for tick control. Volatilization was the principal factor that influenced the dissipation of the pesticide. The sediment bound residues increased with time. Mineralization of {sup 14}C- chlorfenvinphos due to microbial activity showed that the {sup 14}CO{sub 2} production increased with time in biometers flasks with different amounts of sediment. 2,4 - dichloroacetophenone, and 2,4-dichlorobenzaldehyde were identified as degradation products. Isomerization of chlorfenvinphos from isomer Z to E was influenced by sunlight and it affected the efficiency of the pesticide as Z isomer is more active on tick control than E isomer. (author)

  11. VAS operational procedures and results at the Kansas City Satellite Field Services Station

    Science.gov (United States)

    Heckman, B.; Carle, W.; Anthony, R.

    1983-01-01

    An operational assessment of VAS data by using a Man-computer Interactive Data Access System (McIDAS) terminal linked by a 9600 band telephone line is discussed. Seven hours of VAS data were processed and edited daily. Data was scheduled 16 hours a day, 7 days a week; however, during this time period there were very few days with 16 hours of data to evalute. The McIDAS terminal, which has 10 display frames and 5 graphics, provide access to the sounding data processed. These data are processed using two procedures. The dwell sounding data are generated by using all 12 spectral channels with a spin budget of 39. To provide coverage for most of the United States, soundings are made starting at 18 minutes after the hour from approximately 49 deg N to 36 deg N and at 48 minutes after the hour from 36 deg N to 26 deg N. The dwell imaging mode uses 11 channels but the spin budge is 17. With the reduced spin budget, retrievals can be made at 18 or 48 minutes after the hour for approximately 44 deg N to 27 deg N. With these constraints a schedule, of data sets was proposed to use the schedule and how the data set could be used are shown.

  12. Development of procedures to stabilize chlorfenvinphos in model cattle dips

    International Nuclear Information System (INIS)

    Pastor, Y.; Caceres, T.; Merino, R.; Villamar, P.; Castro, R.

    1997-01-01

    The environmental fate and dissipation of chlorfenvinphos acaricide was studied in water and sediment in model cattle dips with recharge, without recharge and with added stabilizers. Chlorfenvinphos concentration decreased with time in all of them, and the monthly recharge at 10% of the initial concentration was inefficient to maintain a concentration that would be effective for tick control. However, the loss of pesticide in the model dip with added phosphate buffer as stabilizer was the least. Volatilization was the principal factor that influenced the dissipation of the pesticide. The sediment bound residues increased with time. Mineralization of 14 C-chlorfenvinphos due to microbial activity showed that the 14 CO 2 production increased with time in biometers flasks with different amounts of sediment. 2,4-Dichloroacetophenone, and 2,4-dichlorobenzaldehyde were identified as degradation products. Isomerization of chlorfenviphos from isomer Z to E was influenced by sunlight. Chlorfenvinphos was stable in aqueous solution for 14 days under pH 4 to 9. Leaching tests demonstrated that the pesticide was not a potential pollutant of ground water. (author)

  13. SAFETY AND EFFECTIVENESS OF SINGLE ANASTOMOSIS DUODENAL SWITCH PROCEDURE: PRELIMINARY RESULT FROM A SINGLE INSTITUTION.

    Science.gov (United States)

    Nelson, Lars; Moon, Rena C; Teixeira, Andre F; Galvão, Manoel; Ramos, Almino; Jawad, Muhammad A

    Single anastomosis duodeno-ileal bypass with sleeve gastrectomy (SADI-S) was introduced into bariatric surgery by Sanchez-Pernaute et al. as an advancement of the biliopancreatic diversion with duodenal switch. To evaluate the SADI-S procedure with regard to weight loss, comorbidity resolution, and complication rate in the super obese population. A retrospective chart review was performed on initial 72 patients who underwent laparoscopic or robot-assisted laparoscopic SADI-S between December 17th, 2013 and July 29th, 2015. A total of 48 female and 21 male patients were included with a mean age of 42.4±10.0 years (range, 22-67). The mean body mass index (BMI) at the time of procedure was 58.4±8.3 kg/m2 (range, 42.3-91.8). Mean length of hospital stay was 4.3±2.6 days (range, 3-24). Thirty-day readmission rate was 4.3% (n=3), due to tachycardia (n=1), deep venous thrombosis (n=1), and viral gastroenteritis (n=1). Thirty-day reoperation rate was 5.8% (n=4) for perforation of the small bowel (n=1), leakage (n=1), duodenal stump leakage (n=1), and diagnostic laparoscopy (n=1). Percentage of excess weight loss (%EWL) was 28.5±8.8 % (range, 13.3-45.0) at three months (n=28), 41.7±11.1 % (range, 19.6-69.6) at six months (n=50), and 61.6±12.0 % (range, 40.1-91.2) at 12 months (n=23) after the procedure. A total of 18 patients (26.1%) presented with type II diabetes mellitus at the time of surgery. Of these patients, 9 (50.0%) had their diabetes resolved, and six (33.3%) had it improved by 6-12 months after SADI-S. SADI-S is a feasible operation with a promising weight loss and diabetes resolution in the super-obese population. Anastomose única em bypass duodenoileal com gastrectomia vertical (SADI-S) foi introduzida na cirurgia bariátrica por Sanchez-Pernaute et al. como um avanço da derivação biliopancreática com switch duodenal. Avaliar o procedimento SADI-S no que diz respeito à perda de peso, resolução de comorbidades e taxa de complicações na popula

  14. Mathematical Model and Calibration Procedure of a PSD Sensor Used in Local Positioning Systems.

    Science.gov (United States)

    Rodríguez-Navarro, David; Lázaro-Galilea, José Luis; Bravo-Muñoz, Ignacio; Gardel-Vicente, Alfredo; Domingo-Perez, Francisco; Tsirigotis, Georgios

    2016-09-15

    Here, we propose a mathematical model and a calibration procedure for a PSD (position sensitive device) sensor equipped with an optical system, to enable accurate measurement of the angle of arrival of one or more beams of light emitted by infrared (IR) transmitters located at distances of between 4 and 6 m. To achieve this objective, it was necessary to characterize the intrinsic parameters that model the system and obtain their values. This first approach was based on a pin-hole model, to which system nonlinearities were added, and this was used to model the points obtained with the nA currents provided by the PSD. In addition, we analyzed the main sources of error, including PSD sensor signal noise, gain factor imbalances and PSD sensor distortion. The results indicated that the proposed model and method provided satisfactory calibration and yielded precise parameter values, enabling accurate measurement of the angle of arrival with a low degree of error, as evidenced by the experimental results.

  15. New Procedure to Develop Lumped Kinetic Models for Heavy Fuel Oil Combustion

    KAUST Repository

    Han, Yunqing

    2016-09-20

    A new procedure to develop accurate lumped kinetic models for complex fuels is proposed, and applied to the experimental data of the heavy fuel oil measured by thermogravimetry. The new procedure is based on the pseudocomponents representing different reaction stages, which are determined by a systematic optimization process to ensure that the separation of different reaction stages with highest accuracy. The procedure is implemented and the model prediction was compared against that from a conventional method, yielding a significantly improved agreement with the experimental data. © 2016 American Chemical Society.

  16. Procedure for Application of Software Reliability Growth Models to NPP PSA

    International Nuclear Information System (INIS)

    Son, Han Seong; Kang, Hyun Gook; Chang, Seung Cheol

    2009-01-01

    As the use of software increases at nuclear power plants (NPPs), the necessity for including software reliability and/or safety into the NPP Probabilistic Safety Assessment (PSA) rises. This work proposes an application procedure of software reliability growth models (RGMs), which are most widely used to quantify software reliability, to NPP PSA. Through the proposed procedure, it can be determined if a software reliability growth model can be applied to the NPP PSA before its real application. The procedure proposed in this work is expected to be very helpful for incorporating software into NPP PSA

  17. The Residual Setup Errors of Different IGRT Alignment Procedures for Head and Neck IMRT and the Resulting Dosimetric Impact

    International Nuclear Information System (INIS)

    Graff, Pierre; Kirby, Neil; Weinberg, Vivian; Chen, Josephine; Yom, Sue S.; Lambert, Louise; Pouliot, Jean

    2013-01-01

    Purpose: To assess residual setup errors during head and neck radiation therapy and the resulting consequences for the delivered dose for various patient alignment procedures. Methods and Materials: Megavoltage cone beam computed tomography (MVCBCT) scans from 11 head and neck patients who underwent intensity modulated radiation therapy were used to assess setup errors. Each MVCBCT scan was registered to its reference planning kVCT, with seven different alignment procedures: automatic alignment and manual registration to 6 separate bony landmarks (sphenoid, left/right maxillary sinuses, mandible, cervical 1 [C1]-C2, and C7-thoracic 1 [T1] vertebrae). Shifts in the different alignments were compared with each other to determine whether there were any statistically significant differences. Then, the dose distribution was recalculated on 3 MVCBCT images per patient for every alignment procedure. The resulting dose-volume histograms for targets and organs at risk (OARs) were compared to those from the planning kVCTs. Results: The registration procedures produced statistically significant global differences in patient alignment and actual dose distribution, calling for a need for standardization of patient positioning. Vertically, the automatic, sphenoid, and maxillary sinuses alignments mainly generated posterior shifts and resulted in mean increases in maximal dose to OARs of >3% of the planned dose. The suggested choice of C1-C2 as a reference landmark appears valid, combining both OAR sparing and target coverage. Assuming this choice, relevant margins to apply around volumes of interest at the time of planning to take into account for the relative mobility of other regions are discussed. Conclusions: Use of different alignment procedures for treating head and neck patients produced variations in patient setup and dose distribution. With concern for standardizing practice, C1-C2 reference alignment with relevant margins around planning volumes seems to be a valid

  18. The Residual Setup Errors of Different IGRT Alignment Procedures for Head and Neck IMRT and the Resulting Dosimetric Impact

    Energy Technology Data Exchange (ETDEWEB)

    Graff, Pierre [Department of Radiation-Oncology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California (United States); Radiation-Oncology, Alexis Vautrin Cancer Center, Vandoeuvre-Les-Nancy (France); Doctoral School BioSE (EA4360), Nancy (France); Kirby, Neil [Department of Radiation-Oncology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California (United States); Weinberg, Vivian [Department of Radiation-Oncology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California (United States); Department of Biostatistics, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California (United States); Chen, Josephine; Yom, Sue S. [Department of Radiation-Oncology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California (United States); Lambert, Louise [Department of Radiation-Oncology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California (United States); Radiation-Oncology, Montreal University Centre, Montreal (Canada); Pouliot, Jean, E-mail: jpouliot@radonc.ucsf.edu [Department of Radiation-Oncology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California (United States)

    2013-05-01

    Purpose: To assess residual setup errors during head and neck radiation therapy and the resulting consequences for the delivered dose for various patient alignment procedures. Methods and Materials: Megavoltage cone beam computed tomography (MVCBCT) scans from 11 head and neck patients who underwent intensity modulated radiation therapy were used to assess setup errors. Each MVCBCT scan was registered to its reference planning kVCT, with seven different alignment procedures: automatic alignment and manual registration to 6 separate bony landmarks (sphenoid, left/right maxillary sinuses, mandible, cervical 1 [C1]-C2, and C7-thoracic 1 [T1] vertebrae). Shifts in the different alignments were compared with each other to determine whether there were any statistically significant differences. Then, the dose distribution was recalculated on 3 MVCBCT images per patient for every alignment procedure. The resulting dose-volume histograms for targets and organs at risk (OARs) were compared to those from the planning kVCTs. Results: The registration procedures produced statistically significant global differences in patient alignment and actual dose distribution, calling for a need for standardization of patient positioning. Vertically, the automatic, sphenoid, and maxillary sinuses alignments mainly generated posterior shifts and resulted in mean increases in maximal dose to OARs of >3% of the planned dose. The suggested choice of C1-C2 as a reference landmark appears valid, combining both OAR sparing and target coverage. Assuming this choice, relevant margins to apply around volumes of interest at the time of planning to take into account for the relative mobility of other regions are discussed. Conclusions: Use of different alignment procedures for treating head and neck patients produced variations in patient setup and dose distribution. With concern for standardizing practice, C1-C2 reference alignment with relevant margins around planning volumes seems to be a valid

  19. 78 FR 20148 - Reporting Procedure for Mathematical Models Selected To Predict Heated Effluent Dispersion in...

    Science.gov (United States)

    2013-04-03

    ... mathematical modeling methods used in predicting the dispersion of heated effluent in natural water bodies. The... COMMISSION Reporting Procedure for Mathematical Models Selected To Predict Heated Effluent Dispersion in... Mathematical Models Selected to Predict Heated Effluent Dispersion in Natural Water Bodies.'' The guide is...

  20. A Procedure for Identification of Appropriate State Space and ARIMA Models Based on Time-Series Cross-Validation

    Directory of Open Access Journals (Sweden)

    Patrícia Ramos

    2016-11-01

    Full Text Available In this work, a cross-validation procedure is used to identify an appropriate Autoregressive Integrated Moving Average model and an appropriate state space model for a time series. A minimum size for the training set is specified. The procedure is based on one-step forecasts and uses different training sets, each containing one more observation than the previous one. All possible state space models and all ARIMA models where the orders are allowed to range reasonably are fitted considering raw data and log-transformed data with regular differencing (up to second order differences and, if the time series is seasonal, seasonal differencing (up to first order differences. The value of root mean squared error for each model is calculated averaging the one-step forecasts obtained. The model which has the lowest root mean squared error value and passes the Ljung–Box test using all of the available data with a reasonable significance level is selected among all the ARIMA and state space models considered. The procedure is exemplified in this paper with a case study of retail sales of different categories of women’s footwear from a Portuguese retailer, and its accuracy is compared with three reliable forecasting approaches. The results show that our procedure consistently forecasts more accurately than the other approaches and the improvements in the accuracy are significant.

  1. Influence of the derivatization procedure on the results of the gaschromatographic fatty acid analysis of human milk and infant formulae.

    Science.gov (United States)

    Kohn, G; van der Ploeg, P; Möbius, M; Sawatzki, G

    1996-09-01

    Many different analytical procedures for fatty acid analysis of infant formulae and human milk are described. The objective was to study possible pitfalls in the use of different acid-catalyzed procedures compared to a base-catalyzed procedure based on sodium-methoxide in methanol. The influence of the different methods on the relative fatty acid composition (wt% of total fatty acids) and the total fatty acid recovery rate (expressed as % of total lipids) was studied in two experimental LCP-containing formulae and a human milk sample. MeOH/HCl-procedures were found to result in an incomplete transesterification of triglycerides, if an additional nonpolar solvent like toluene or hexane is not added and a water-free preparation is not guaranteed. In infant formulae the low transesterification of triglycerides (up to only 37%) could result in an 100%-overestimation of the relative amount of LCP, if these fatty acids primarily derive from phospholipids. This is the case in infant formulae containing egg lipids as raw materials. In formula containing fish oils and in human milk the efficacy of esterification results in incorrect absolute amounts of fatty acids, but has no remarkable effect on the relative fatty acid distribution. This is due to the fact that in these samples LCP are primarily bound to triglycerides. Furthermore, in formulae based on butterfat the derivatization procedure should be designed in such a way that losses of short-chain fatty acids due to evaporation steps can be avoided. The procedure based on sodium methoxide was found to result in a satisfactory (about 90%) conversion of formula lipids and a reliable content of all individual fatty acids. Due to a possibly high amount of free fatty acids in human milk, which are not methylated by sodium-methoxide, caution is expressed about the use of this reagent for fatty acid analysis of mothers milk. It is concluded that accurate fatty acid analysis of infant formulae and human milk requires a careful

  2. Automatic Multi-Scale Calibration Procedure for Nested Hydrological-Hydrogeological Regional Models

    Science.gov (United States)

    Labarthe, B.; Abasq, L.; Flipo, N.; de Fouquet, C. D.

    2014-12-01

    Large hydrosystem modelling and understanding is a complex process depending on regional and local processes. A nested interface concept has been implemented in the hydrosystem modelling platform for a large alluvial plain model (300 km2) part of a 11000 km2 multi-layer aquifer system, included in the Seine basin (65000 km2, France). The platform couples hydrological and hydrogeological processes through four spatially distributed modules (Mass balance, Unsaturated Zone, River and Groundwater). An automatic multi-scale calibration procedure is proposed. Using different data sets from regional scale (117 gauging stations and 183 piezometers over the 65000 km2) to the intermediate scale(dense past piezometric snapshot), it permits the calibration and homogenization of model parameters over scales.The stepwise procedure starts with the optimisation of the water mass balance parameters at regional scale using a conceptual 7 parameters bucket model coupled with the inverse modelling tool PEST. The multi-objective function is derived from river discharges and their de-composition by hydrograph separation. The separation is performed at each gauging station using an automatic procedure based one Chapman filter. Then, the model is run at the regional scale to provide recharge estimate and regional fluxes to the groundwater local model. Another inversion method is then used to determine the local hydrodynamic parameters. This procedure used an initial kriged transmissivity field which is successively updated until the simulated hydraulic head distribution equals a reference one obtained by krigging. Then, the local parameters are upscaled to the regional model by renormalisation procedure.This multi-scale automatic calibration procedure enhances both the local and regional processes representation. Indeed, it permits a better description of local heterogeneities and of the associated processes which are transposed into the regional model, improving the overall performances

  3. New Inference Procedures for Semiparametric Varying-Coefficient Partially Linear Cox Models

    Directory of Open Access Journals (Sweden)

    Yunbei Ma

    2014-01-01

    Full Text Available In biomedical research, one major objective is to identify risk factors and study their risk impacts, as this identification can help clinicians to both properly make a decision and increase efficiency of treatments and resource allocation. A two-step penalized-based procedure is proposed to select linear regression coefficients for linear components and to identify significant nonparametric varying-coefficient functions for semiparametric varying-coefficient partially linear Cox models. It is shown that the penalized-based resulting estimators of the linear regression coefficients are asymptotically normal and have oracle properties, and the resulting estimators of the varying-coefficient functions have optimal convergence rates. A simulation study and an empirical example are presented for illustration.

  4. [Functional results of cryosurgical procedures in rhegmatogenous retinal detachment including macula region - our experience].

    Science.gov (United States)

    Chrapek, O; Sín, M; Jirková, B; Jarkovský, J; Rehák, J

    2013-10-01

    Aim of this study is to evaluate retrospectively functional results of cryosurgical treatment of uncomplicated, idiopathic rhegmatogenous retinal detachment including macula region in phakic patients operated on at the Department of Ophthalmology, Faculty Hospital, Palacký University, Olomouc, Czech Republic, E.U., during the period 2002 -2013, and to evaluate the significance of the macula detachment duration for the final visual acuity. In the study group were included 56 eyes of 56 patients operated in the years 2003 - 2012 at the Department of Ophthalmology, Faculty Hospital, Palacký University, Olomouc. All patients were phakic and in all of them, the retinal detachment including the macula region was diagnosed. The mean follow-up period of the patients was 8,75 months. The initial and final visual acuity testing were performed. Comparing the initial and final visual acuity we rated the level of the visual acuity change. The result was stated as improved, if the visual acuity improved by 1 or more lines on the ETDRS chart. The result was rated as stabilized, if the visual acuity remained the same or it changed by 1 line of the ETDRS chart only. The result was evaluated as worsened, if the visual acuity decreased by 1 or more lines of the ETDRS chart. In the followed-up group, the authors compared visual acuity levels in patients with the macula detachment duration 10 days and 11 days. For the statistical evaluation of achieved results, the Mann - Whitney U test was used. The visual acuity improved in 49 (87 %), did not changed in 5 (9 %) and worsened in 2 (4 %) patients. The patients with macula detachment duration 10 days achieved statistically significant better visual acuity than patients with macula detachment duration 11 days. Patients with macula detachment duration 10 days have better prognosis for functional result than patients with macula detachment duration 11 days.

  5. Evaluation of method of serum thyreostimuline determination: discussion of procedure and results

    International Nuclear Information System (INIS)

    Savoie, J.C.; Laurent, M.F.; Henry, R.; Meriadec, B.; Leger, F.; CEA Centre d'Etudes Nucleaires de Saclay, 91 - Gif-sur-Yvette

    1975-01-01

    The aim of this work is to estimate the commercial method developed by the CEA for the radioimmunological determination of serum thyreostimuline. The study covers a year of clinical use. The method is described and the results given for more than 1000 determinations, performed on both reference and pathological subjects. This method is found to have met the needs of clinical investigation [fr

  6. A Procedure for Building Product Models in Intelligent Agent-based OperationsManagement

    DEFF Research Database (Denmark)

    Hvam, Lars; Riis, Jesper; Malis, Martin

    2003-01-01

    This article presents a procedure for building product models to support the specification processes dealing with sales, design of product variants and production preparation. The procedure includes, as the first phase, an analysis and redesign of the business processes that are to be supported...... by product models. The next phase includes an analysis of the product assortment, and the set up of a so-called product master. Finally the product model is designed and implemented by using object oriented modelling. The procedure is developed in order to ensure that the product models constructed are fit...... for the business processes they support, and properly structured and documented in order to facilitate the maintenance and further development of the systems. The research has been carried out at the Centre for Industrialisation of Engineering, Department of Manufacturing Engineering, Technical University...

  7. Obtaining manufactured geometries of deep-drawn components through a model updating procedure using geometric shape parameters

    Science.gov (United States)

    Balla, Vamsi Krishna; Coox, Laurens; Deckers, Elke; Plyumers, Bert; Desmet, Wim; Marudachalam, Kannan

    2018-01-01

    The vibration response of a component or system can be predicted using the finite element method after ensuring numerical models represent realistic behaviour of the actual system under study. One of the methods to build high-fidelity finite element models is through a model updating procedure. In this work, a novel model updating method of deep-drawn components is demonstrated. Since the component is manufactured with a high draw ratio, significant deviations in both profile and thickness distributions occurred in the manufacturing process. A conventional model updating, involving Young's modulus, density and damping ratios, does not lead to a satisfactory match between simulated and experimental results. Hence a new model updating process is proposed, where geometry shape variables are incorporated, by carrying out morphing of the finite element model. This morphing process imitates the changes that occurred during the deep drawing process. An optimization procedure that uses the Global Response Surface Method (GRSM) algorithm to maximize diagonal terms of the Modal Assurance Criterion (MAC) matrix is presented. This optimization results in a more accurate finite element model. The advantage of the proposed methodology is that the CAD surface of the updated finite element model can be readily obtained after optimization. This CAD model can be used for carrying out analysis, as it represents the manufactured part more accurately. Hence, simulations performed using this updated model with an accurate geometry, will therefore yield more reliable results.

  8. Proximal First Metatarsal Osteotomy and Mc Bride Procedure in Hallux Valgus: 5-years results of 25 cases

    Directory of Open Access Journals (Sweden)

    Ali Yeganeh

    2016-05-01

    Full Text Available More than 130 operations have been described for the treatment of hallux valgus, However, no evidence that any of these methods of treatment are superior to the others has been described, excepting studies in the long term. The aim of this study was to analyse a series of patients who had undergone Proximal osteotomy of first metatarsal and Mc Bride procedure and had been followed up for 5 years. In This prospective study During a 6 years period, (2005-2010, 25 feet in 24 cases with hallux valgus underwent Proximal first metatarsal osteotomy and MCbride procedure, With a mean follow-up of 3/5±1/5 years. The cases were evaluated by American Orthopaedics Foot & Ankle Society HalluxMetatarsophalangeal-interphalangeal scale (AOFAS/HMI. Pre and post hallux valgus angle (HVA, intermetatarsal angle (1-2IMA, and the correlation between the angles and patient satisfaction were statistically evaluated. The mean angular corrections for hallux valgus (HVA, and intermetatarsal angle (IMA were 28 and 10/6 degrees respectively. 13 Patients reported good to excellent results, while in 11 cases dissatisfaction were reported. Proximal first metatarsal osteotomy and Mc Bride procedure for hallux valgus is an acceptable procedure in Patients with hallux valgus deformity correction.Pain and first MTP joint contractures are two main side effects.

  9. SITE-94. Discrete-feature modelling of the Aespoe site: 4. Source data and detailed analysis procedures

    International Nuclear Information System (INIS)

    Geier, J.E.

    1996-12-01

    Specific procedures and source data are described for the construction and application of discrete-feature hydrological models for the vicinity of Aespoe. Documentation is given for all major phases of the work, including: Statistical analyses to develop and validate discrete-fracture network models, Preliminary evaluation, construction, and calibration of the site-scale model based on the SITE-94 structural model of Aespoe, Simulation of multiple realizations of the integrated model, and variations, to predict groundwater flow, and Evaluation of near-field and far-field parameters for performance assessment calculations. Procedures are documented in terms of the computer batch files and executable scripts that were used to perform the main steps in these analyses, to provide for traceability of results that are used in the SITE-94 performance assessment calculations. 43 refs

  10. RESULTS OF SHOULDER STABILIZATION BY A MODIFIED BRISTOW - LATARJET PROCEDURE WITH ARTHROSCOPY

    Directory of Open Access Journals (Sweden)

    R. V. Gladkov

    2014-01-01

    Full Text Available The authors describe the minimally invasive technique for Bristow-Latarjet bone unfree autoplasty with arthroscopy in patients with bone loss more than 25% of anterior-posterior diameter of the glenoid, the poor quality of the capsule or deep defects of Hill-Sachs. The analysis of the early results of treatment in 19 patients and midterm results - in 13 soldiers operated in 2011-2014. Features of the proposed technique are the shortening of surgical approach and the reduction of subscapularis muscle damage. In addition, arthroscopic support allows to attain the precision location of the graft relative to the articular surface of scapula, at the same time restoring the damaged anatomy SLAP, rotator cuff tendons and posterior labrum and restore shoulder ligaments tension and isolate bone graft from the joint cavity, contributing to a better articulation of the humeral head and reducing the risk of nonunion and resorption.

  11. A computational model to investigate assumptions in the headturn preference procedure

    Directory of Open Access Journals (Sweden)

    Christina eBergmann

    2013-10-01

    Full Text Available In this paper we use a computational model to investigate four assumptions that are tacitly present in interpreting the results of studies on infants' speech processing abilities using the Headturn Preference Procedure (HPP: (1 behavioural differences originate in different processing; (2 processing involves some form of recognition; (3 words are segmented from connected speech; and (4 differences between infants should not affect overall results. In addition, we investigate the impact of two potentially important aspects in the design and execution of the experiments: (a the specific voices used in the two parts on HPP experiments (familiarisation and test and (b the experimenter's criterion for what is a sufficient headturn angle. The model is designed to be maximise cognitive plausibility. It takes real speech as input, and it contains a module that converts the output of internal speech processing and recognition into headturns that can yield real-time listening preference measurements. Internal processing is based on distributed episodic representations in combination with a matching procedure based on the assumptions that complex episodes can be decomposed as positive weighted sums of simpler constituents. Model simulations show that the first assumptions hold under two different definitions of recognition. However, explicit segmentation is not necessary to simulate the behaviours observed in infant studies. Differences in attention span between infants can affect the outcomes of an experiment. The same holds for the experimenter's decision criterion. The speakers used in experiments affect outcomes in complex ways that require further investigation. The paper ends with recommendations for future studies using the HPP.

  12. Spirometry in Healthy Subjects: Do Technical Details of the Test Procedure Affect the Results?

    Science.gov (United States)

    Sipoli, Luciana; Martinez, Larissa; Donária, Leila; Probst, Vanessa Suziane; Moreira, Graciane Laender; Pitta, Fabio

    2014-01-01

    Introduction Spirometry should follow strict quality criteria. The American Thoracic Society (ATS) recommends the use of a noseclip; however there are controversies about its need. ATS also indicates that tests should be done in the sitting position, but there are no recommendations neither about position of the upper limbs and lower limbs nor about who should hold the mouthpiece while performing the maneuvers: evaluated subject or evaluator. Objectives To compare noseclip use or not, different upper and lower limbs positions and who holds the mouthpiece, verifying if these technical details affect spirometric results in healthy adults. Methods One hundred and three healthy individuals (41 men; age: 47 [33–58] years; normal lung function: FEV1/FVC = 83±5, FEV1 = 94 [88–104]%predicted, FVC = 92 [84–102]%predicted) underwent a protocol consisting of four spirometric comparative analysis in the sitting position: 1) maximum voluntary ventilation (MVV) with vs without noseclip; 2) FVC performed with vs without upper limbs support; 3) FVC performed with lower limbs crossed vs lower limbs in neutral position; 4) FVC, slow vital capacity and MVV comparing the evaluated subject holding the mouthpiece vs evaluator holding it. Results Different spirometric variables presented statistically significant difference (p<0.05) when analysing the four comparisons; however, none of them showed any variation larger than those considered as acceptable according to the ATS reproducibility criteria. Conclusions There was no relevant variation in spirometric results when analyzing technical details such as noseclip use during MVV, upper and lower limb positions and who holds the mouthpiece when performing the tests in healthy adults. PMID:25244437

  13. Reconstruction of the chronically insufficient anterior cruciate ligament: long term results of the Eriksson procedure.

    Science.gov (United States)

    Natri, A; Järvinen, M; Lehto, M; Kannus, P

    1996-01-01

    Thirty-two patients (26 men and 6 women) with symptoms due to chronic insufficiency of the anterior cruciate ligament were treated by reconstruction using the medial one-third of the patellar tendon. The average delay between injury and operation was 4.8 years. Prior to this, 28 operations had been carried out on the knees of 20 of the patients. At follow up, at an average of 6.6 years after reconstruction, 50% were satisfied subjectively with the end result, and 57% were excellent or good on the Lysholm score. The Lachman test showed that 50% were completely stable and none had severe laxity. The anterior drawer test was negative in 59% and only one had moderate laxity. The pivot shift was negative in 69% and only 2 were 2+ positive. Twenty-one of the 29 patients who were active in sport before their injury were able to continue their activity at the same or a reduced level.

  14. Energy efficiency improvement procedures and audit results of electrical, thermal and solar applications in Palestine

    International Nuclear Information System (INIS)

    Ibrik, I.H.; Mahmoud, M.M.

    2005-01-01

    Energy conservation in utilities has played a vital role in improving energy efficiency in the industrial, commercial and residential sectors. The electrical energy consumption in Palestine has increased sharply in the past few years and achieved by the end of 2001 to 10% per year. It is expected that this percentage will increase to about 12% if the current political situation will end hopefully with peace. Modern energy efficient technologies are needed for the national energy policy. Such technologies are investigated in this paper. Implementing of a national 3 years project aiming at energy efficiency improvement in residential and industrial sectors as well as in public utilities, which include wide range of diversified audits and power measurements, had led to creating this paper. Measurement and audit results had shown that the total conservation potential in these sectors is around 15% of the total energy consumption. The associated costs of the investment in this field are relatively low and correspond to a pay back period varying in the range from 6 to 36 months. Consequently, the energy conservation policy will be seriously improved in the forthcoming years. It is estimated that 10% of the new energy purchasing capacity will be reduced accordingly

  15. Nutritional intervention programme among a Japanese-Brazilian community: procedures and results according to gender.

    Science.gov (United States)

    Damião, Renata; Sartorelli, Daniela Saes; Hirai, Amélia; Massimino, Flávia; Poletto, Juliana; Bevilacqua, Marselle Rodrigues; Chaim, Rita; de Salvo, Vera Lúcia Morais Antonio; Asakura, Leiko; Ferreira, Sandra Roberta Gouveia; Andreoni, Solange; Gimeno, Suely Godoy Agostinho

    2010-09-01

    To describe the results of a nutritional intervention programme among Japanese-Brazilians according to gender. A non-controlled experimental study. The research included three points of clinical, nutritional and physical activity evaluation: at baseline (in 2005), after the first year and at the end of the second year (in 2007). The paired Student t test and multiple linear regression analysis were used to evaluate changes in the subjects' profile (clinical, nutritional and physical activity variables). Japanese-Brazilians (n 575) of both genders, aged over 30 years. We verified statistically significant reductions in body weight (0.9 kg), waist circumference (2.9 cm), blood pressure, fasting blood glucose (>3 mg/dl) and total cholesterol (>20 mg/dl) and its fractions, in both genders. We also found reductions in intake of energy (among men), protein (among women) and fat (both genders) and increases in intake of total fibre (among women) and carbohydrate (among men). The intervention programme indicated meaningful benefits for the intervention subjects, with changes in their habits that led to a 'healthier' lifestyle positively impacting their nutritional and metabolic profile.

  16. A model for analysing factors which may influence quality management procedures in higher education

    Directory of Open Access Journals (Sweden)

    Cătălin MAICAN

    2015-12-01

    Full Text Available In all universities, the Office for Quality Assurance defines the procedure for assessing the performance of the teaching staff, with a view to establishing students’ perception as regards the teachers’ activity from the point of view of the quality of the teaching process, of the relationship with the students and of the assistance provided for learning. The present paper aims at creating a combined model for evaluation, based on Data Mining statistical methods: starting from the findings revealed by the evaluations teachers performed to students, using the cluster analysis and the discriminant analysis, we identified the subjects which produced significant differences between students’ grades, subjects which were subsequently subjected to an evaluation by students. The results of these analyses allowed the formulation of certain measures for enhancing the quality of the evaluation process.

  17. Precipitation projections under GCMs perspective and Turkish Water Foundation (TWF) statistical downscaling model procedures

    Science.gov (United States)

    Dabanlı, İsmail; Şen, Zekai

    2018-04-01

    The statistical climate downscaling model by the Turkish Water Foundation (TWF) is further developed and applied to a set of monthly precipitation records. The model is structured by two phases as spatial (regional) and temporal downscaling of global circulation model (GCM) scenarios. The TWF model takes into consideration the regional dependence function (RDF) for spatial structure and Markov whitening process (MWP) for temporal characteristics of the records to set projections. The impact of climate change on monthly precipitations is studied by downscaling Intergovernmental Panel on Climate Change-Special Report on Emission Scenarios (IPCC-SRES) A2 and B2 emission scenarios from Max Plank Institute (EH40PYC) and Hadley Center (HadCM3). The main purposes are to explain the TWF statistical climate downscaling model procedures and to expose the validation tests, which are rewarded in same specifications as "very good" for all stations except one (Suhut) station in the Akarcay basin that is in the west central part of Turkey. Eventhough, the validation score is just a bit lower at the Suhut station, the results are "satisfactory." It is, therefore, possible to say that the TWF model has reasonably acceptable skill for highly accurate estimation regarding standard deviation ratio (SDR), Nash-Sutcliffe efficiency (NSE), and percent bias (PBIAS) criteria. Based on the validated model, precipitation predictions are generated from 2011 to 2100 by using 30-year reference observation period (1981-2010). Precipitation arithmetic average and standard deviation have less than 5% error for EH40PYC and HadCM3 SRES (A2 and B2) scenarios.

  18. Hirschsprung’s Disease and Rehbein’s Procedure – Our Results in the Last 30 Years

    OpenAIRE

    Žganjer, Mirko; Cigit, Irenej; Car, Andrija; Višnjić, Stjepan; Butković, Diana

    2006-01-01

    Hirschsprung’s disease is congenital anomaly of the intestine and Harald Hirschsprung gave the first description of this disease1. The aim of this follow-up study was to evaluate the results of Rehbein’s procedure in the treatment of Hirschsprung’s disease in the last 30 years in Children’s Hospital Zagreb. Hirschsprung’s disease is congenital intestinal aganglionosis as the results of arrested fetal development of the myenteric nervous system. Hirschsprung’s disease is affecting ...

  19. Modelling and analysis of transient state during improved coupling procedure with the grid for DFIG based wind turbine generator

    Science.gov (United States)

    Kammoun, Soulaymen; Sallem, Souhir; Ben Ali Kammoun, Mohamed

    2017-11-01

    The aim of this study is to enhance DFIG based Wind Energy Conversion Systems (WECS) dynamics during grid coupling. In this paper, a system modelling and a starting/coupling procedure for this generator to the grid are proposed. The proposed non-linear system is a variable structure system (VSS) and has two different states, before and after coupling. So, two different state models are given to the system to analyse transient stability during the coupling. The given model represents well the transient state of the machine, through which, a behaviour assessment of the generator before, during and after connection is given based on simulation results. For this, a 300 kW DFIG based wind generation system model was simulated on the Matlab/SIMULINK environment. We judge the proposed procedure to be practical, smooth and stability improved.

  20. Evaluation of the results and complications of the Latarjet procedure for recurrent anterior dislocation of the shoulder

    Directory of Open Access Journals (Sweden)

    Luciana Andrade da Silva

    2015-12-01

    Full Text Available ABSTRACT OBJECTIVE: Evaluate the results and complications of Latarjet procedure in patients with anterior recurrent dislocation of the shoulder. METHODS: Fifty-one patients (52 shoulders with anterior recurrent dislocation, surgically treated by Latarjet procedure, were analyzed retrospectively. The average follow-up time was 22 months, range 12-66 months; The age range was 15-59 years with a mean of 31; regarding sex, 42 (82.4% patients were male and nine (17.6% were female. The dominant side was affected in 29 (55.8% shoulders. Regarding the etiology, 48 (92.3% reported trauma and four (7.6% had the first episode after a convulsion. RESULTS: The average elevation, lateral rotation and medial rotation of the operated shoulder were, respectively, 146° (60-80°, 59° (0-85° and T8 (T5 gluteus, with statistical significance for decreased range of motion in all planes, compared with the other side. The scores of Rowe and UCLA were 90.6 and 31.4, respectively, in the postoperative period. Eleven shoulders (21.2% had poor results: signs of instability (13.4%, non-union (11.5% and early loosening of the synthesis material (1.9%. There was a correlation between poor results and convulsive patients ( p = 0.026. CONCLUSION: We conclude that the Latarjet procedure for correction of anterior recurrent dislocation leads to good and excellent results in 82.7% of cases. Complications are related to errors in technique.

  1. Late Results of Cox Maze III Procedure in Patients with Atrial Fibrillation Associated with Structural Heart Disease.

    Science.gov (United States)

    Gomes, Gustavo Gir; Gali, Wagner Luis; Sarabanda, Alvaro Valentim Lima; Cunha, Claudio Ribeiro da; Kessler, Iruena Moraes; Atik, Fernando Antibas

    2017-07-01

    Cox-Maze III procedure is one of the surgical techniques used in the surgical treatment of atrial fibrillation (AF). To determine late results of Cox-Maze III in terms of maintenance of sinus rhythm, and mortality and stroke rates. Between January 2006 and January 2013, 93 patients were submitted to the cut-and-sew Cox-Maze III procedure in combination with structural heart disease repair. Heart rhythm was determined by 24-hour Holter monitoring. Procedural success rates were determined by longitudinal methods and recurrence predictors by multivariate Cox regression models. Thirteen patients that obtained hospital discharge alive were excluded due to lost follow-up. The remaining 80 patients were aged 49.9 ± 12 years and 47 (58.7%) of them were female. Involvement of mitral valve and rheumatic heart disease were found in 67 (83.7%) and 63 (78.7%) patients, respectively. Seventy patients (87.5%) had persistent or long-standing persistent AF. Mean follow-up with Holter monitoring was 27.5 months. There were no hospital deaths. Sinus rhythm maintenance rates were 88%, 85.1% and 80.6% at 6 months, 24 months and 36 months, respectively. Predictors of late recurrence of AF were female gender (HR 3.52; 95% CI 1.21-10.25; p = 0.02), coronary artery disease (HR 4.73 95% CI 1.37-16.36; p = 0.01) and greater left atrium diameter (HR 1.05; 95% CI 1.01-1.09; p = 0.02). Actuarial survival was 98.5% at 12, 24 and 48 months and actuarial freedom from stroke was 100%, 100% and 97.5% in the same time frames. The Cox-Maze III procedure, in our experience, is efficacious for sinus rhythm maintenance, with very low late mortality and stroke rates. A operação de Cox-Maze III é uma das variantes técnicas no tratamento cirúrgico da fibrilação atrial (FA). Estudar os resultados tardios da operação de Cox-Maze III, quanto à eficácia na manutenção de ritmo sinusal e taxas de mortalidade e acidente vascular cerebral (AVC). Entre janeiro de 2006 a janeiro de 2013, 93 pacientes

  2. A new 99mTc-red blood cell labeling procedure for cardiac blood pool imaging: Clinical results

    International Nuclear Information System (INIS)

    Kelbaek, H.; Buelow, K.; Aldershvile, J.; Moegelyang, J.; Nielsen, S.L.; Copenhagen Univ.

    1989-01-01

    The first clinical results of a new 99m Tc-red blood cell labeling procedure avoiding cell centrifugation are presented. One ml heparinized blood samples were incubated with small amounts of a stannous kit. By titration studies, ideal quantities of sodium hypochlorite for oxidation of extracellular tin and of EDTA as stabilizer of the label were found. The Cl - concentration and pH of the labeled blood were acceptable, and EDTA increased labeling yield and stability determined in vitro by a few percent. The new procedure gave a slightly higher labeling yield than a current technique using centrifugation of cells. Labeling efficiency expressed as cell bound/total activity was 96.6%±1.3% in healthy subjects and 95.5%±2.2% in cardiac patients and remained high for 2 h after reinjection. The biological halflife of labeled cells following the new procedure was 11-12 h rendering it suitable for serial determinations of radionuclide cardiography. (orig.)

  3. Requirements for Computer Based-Procedures for Nuclear Power Plant Field Operators Results from a Qualitative Study

    Energy Technology Data Exchange (ETDEWEB)

    Katya Le Blanc; Johanna Oxstrand

    2012-05-01

    Although computer-based procedures (CBPs) have been investigated as a way to enhance operator performance on procedural tasks in the nuclear industry for almost thirty years, they are not currently widely deployed at United States utilities. One of the barriers to the wide scale deployment of CBPs is the lack of operational experience with CBPs that could serve as a sound basis for justifying the use of CBPs for nuclear utilities. Utilities are hesitant to adopt CBPs because of concern over potential costs of implementation, and concern over regulatory approval. Regulators require a sound technical basis for the use of any procedure at the utilities; without operating experience to support the use CBPs, it is difficult to establish such a technical basis. In an effort to begin the process of developing a technical basis for CBPs, researchers at Idaho National Laboratory are partnering with industry to explore CBPs with the objective of defining requirements for CBPs and developing an industry-wide vision and path forward for the use of CBPs. This paper describes the results from a qualitative study aimed at defining requirements for CBPs to be used by field operators and maintenance technicians.

  4. Requirements for Computer Based-Procedures for Nuclear Power Plant Field Operators. Results from a Qualitative Study

    International Nuclear Information System (INIS)

    Le Blanc, Katya; Oxstrand, J.H.; Waicosky, T.

    2012-01-01

    Although computer-based procedures (CBPs) have been investigated as a way to enhance operator performance on procedural tasks in the nuclear industry for almost thirty years, they are not currently widely deployed at United States utilities. One of the barriers to the wide scale deployment of CBPs is the lack of operational experience with CBPs that could serve as a sound basis for justifying the use of CBPs for nuclear utilities. Utilities are hesitant to adopt CBPs because of concern over potential costs of implementation, and concern over regulatory approval. Regulators require a sound technical basis for the use of any procedure at the utilities; without operating experience to support the use CBPs, it is difficult to establish such a technical basis. In an effort to begin the process of developing a technical basis for CBPs, researchers at Idaho National Laboratory are partnering with industry to explore CBPs with the objective of defining requirements for CBPs and developing an industry-wide vision and path forward for the use of CBPs. This paper describes the results from a qualitative study aimed at defining requirements for CBPs to be used by field operators and maintenance technicians. (author)

  5. Procedural guide for modelling and analyzing the flight characteristics of a helicopter design using Flightlab

    OpenAIRE

    McVaney, Gary P.

    1993-01-01

    Approved for public release; distribution is unlimited. This thesis presents one method for modelling and analyzing a helicopter design using Flightlab. Flightlab is a computer program that provides for engineering design, analysis and simulation of aircraft using non-linear dynamic modeling techniques. The procedure to model a single main rotor helicopter is outlined using the sample helicopter design in the book 'Helicopter Performance, Stability, and Control' by Ray Prouty. The analysis...

  6. The Chain-Link Fence Model: A Framework for Creating Security Procedures

    OpenAIRE

    Houghton, Robert F.

    2013-01-01

    A long standing problem in information technology security is how to help reduce the security footprint. Many specific proposals exist to address specific problems in information technology security. Most information technology solutions need to be repeatable throughout the course of an information systems lifecycle. The Chain-Link Fence Model is a new model for creating and implementing information technology procedures. This model was validated by two different methods: the first being int...

  7. A Markov Chain Model for evaluating the effectiveness of randomized surveillance procedures

    Energy Technology Data Exchange (ETDEWEB)

    Edmunds, T.A.

    1994-01-01

    A Markov Chain Model has been developed to evaluate the effectiveness of randomized surveillance procedures. The model is applicable for surveillance systems that monitor a collection of assets by randomly selecting and inspecting the assets. The model provides an estimate of the detection probability as a function of the amount of time that an adversary would require to steal or sabotage the asset. An interactive computer code has been written to perform the necessary computations.

  8. A network society communicative model for optimizing the Refugee Status Determination (RSD procedures

    Directory of Open Access Journals (Sweden)

    Andrea Pacheco Pacífico

    2013-01-01

    Full Text Available This article recommends a new way to improve Refugee Status Determination (RSD procedures by proposing a network society communicative model based on active involvement and dialogue among all implementing partners. This model, named after proposals from Castells, Habermas, Apel, Chimni, and Betts, would be mediated by the United Nations High Commissioner for Refugees (UNHCR, whose role would be modeled after that of the International Committee of the Red Cross (ICRC practice.

  9. Sensitivity of tropical convection in cloud-resolving WRF simulations to model physics and forcing procedures

    Science.gov (United States)

    Endo, S.; Lin, W.; Jackson, R. C.; Collis, S. M.; Vogelmann, A. M.; Wang, D.; Oue, M.; Kollias, P.

    2017-12-01

    Tropical convection is one of the main drivers of the climate system and recognized as a major source of uncertainty in climate models. High-resolution modeling is performed with a focus on the deep convection cases during the active monsoon period of the TWP-ICE field campaign to explore ways to improve the fidelity of convection permitting tropical simulations. Cloud resolving model (CRM) simulations are performed with WRF modified to apply flexible configurations for LES/CRM simulations. We have enhanced the capability of the forcing module to test different implementations of large-scale vertical advective forcing, including a function for optional use of large-scale thermodynamic profiles and a function for the condensate advection. The baseline 3D CRM configurations are, following Fridlind et al. (2012), driven by observationally-constrained ARM forcing and tested with diagnosed surface fluxes and fixed sea-surface temperature and prescribed aerosol size distributions. After the spin-up period, the simulations follow the observed precipitation peaks associated with the passages of precipitation systems. Preliminary analysis shows that the simulation is generally not sensitive to the treatment of the large-scale vertical advection of heat and moisture, while more noticeable changes in the peak precipitation rate are produced when thermodynamic profiles above the boundary layer were nudged to the reference profiles from the forcing dataset. The presentation will explore comparisons with observationally-based metrics associated with convective characteristics and examine the model performance with a focus on model physics, doubly-periodic vs. nested configurations, and different forcing procedures/sources. A radar simulator will be used to understand possible uncertainties in radar-based retrievals of convection properties. Fridlind, A. M., et al. (2012), A comparison of TWP-ICE observational data with cloud-resolving model results, J. Geophys. Res., 117, D05204

  10. MODELING IN MAPLE AS THE RESEARCHING MEANS OF FUNDAMENTAL CONCEPTS AND PROCEDURES IN LINEAR ALGEBRA

    Directory of Open Access Journals (Sweden)

    Vasil Kushnir

    2016-05-01

    Full Text Available The article is devoted to binary technology and "fundamental training technology." Binary training refers to the simultaneous teaching of mathematics and computer science, for example differential equations and Maple, linear algebra and Maple. Moreover the system of traditional course of Maple is not performed. The use of the opportunities of Maple-technology in teaching mathematics is based on the following fundamental concepts of computer science as an algorithm, program, a linear program, cycle, branching, relative operators, etc. That’s why only a certain system of command operators in Maple is considered. They are necessary for fundamental concepts of linear algebra and differential equations studying in Maple-environment. Relative name - "the technology of fundamental training" reflects the study of fundamental mathematical concepts and procedures that express the properties of these concepts in Maple-environment. This article deals with the study of complex fundamental concepts of linear algebra (determinant of the matrix and algorithm of its calculation, the characteristic polynomial of the matrix and the eigenvalues of matrix, canonical form of characteristic matrix, eigenvectors of matrix, elementary divisors of the characteristic matrix, etc., which are discussed in the appropriate courses briefly enough, and sometimes are not considered at all, but they are important in linear systems of differential equations, asymptotic methods for solving differential equations, systems of linear equations. Herewith complex and voluminous procedures of finding of these linear algebra concepts embedded in Maple can be performed as a result of a simple command-operator. Especially important issue is building matrix to canonical form. In fact matrix functions are effectively reduced to the functions of the diagonal matrix or matrix in Jordan canonical form. These matrices are used to rise a square matrix to a power, to extract the roots of the n

  11. FRP-RC Beam in Shear: Mechanical Model and Assessment Procedure for Pseudo-Ductile Behavior

    Directory of Open Access Journals (Sweden)

    Floriana Petrone

    2014-07-01

    Full Text Available This work deals with the development of a mechanics-based shear model for reinforced concrete (RC elements strengthened in shear with fiber-reinforced polymer (FRP and a design/assessment procedure capable of predicting the failure sequence of resisting elements: the yielding of existing transverse steel ties and the debonding of FRP sheets/strips, while checking the corresponding compressive stress in concrete. The research aims at the definition of an accurate capacity equation, consistent with the requirement of the pseudo-ductile shear behavior of structural elements, that is, transverse steel ties yield before FRP debonding and concrete crushing. For the purpose of validating the proposed model, an extended parametric study and a comparison against experimental results have been conducted: it is proven that the common accepted rule of assuming the shear capacity of RC members strengthened in shear with FRP as the sum of the maximum contribution of both FRP and stirrups can lead to an unsafe overestimation of the shear capacity. This issue has been pointed out by some authors, when comparing experimental shear capacity values with the theoretical ones, but without giving a convincing explanation of that. In this sense, the proposed model represents also a valid instrument to better understand the mechanical behavior of FRP-RC beams in shear and to calculate their actual shear capacity.

  12. Implementation of a combined association-linkage model for quantitative traits in linear mixed model procedures of statistical packages

    NARCIS (Netherlands)

    Beem, A. Leo; Boomsma, Dorret I.

    2006-01-01

    A transmission disequilibrium test for quantitative traits which combines association and linkage analyses is currently available in several dedicated software packages. We describe how to implement such models in linear mixed model procedures that are available in widely used statistical packages

  13. Analyzing longitudinal data with the linear mixed models procedure in SPSS.

    Science.gov (United States)

    West, Brady T

    2009-09-01

    Many applied researchers analyzing longitudinal data share a common misconception: that specialized statistical software is necessary to fit hierarchical linear models (also known as linear mixed models [LMMs], or multilevel models) to longitudinal data sets. Although several specialized statistical software programs of high quality are available that allow researchers to fit these models to longitudinal data sets (e.g., HLM), rapid advances in general purpose statistical software packages have recently enabled analysts to fit these same models when using preferred packages that also enable other more common analyses. One of these general purpose statistical packages is SPSS, which includes a very flexible and powerful procedure for fitting LMMs to longitudinal data sets with continuous outcomes. This article aims to present readers with a practical discussion of how to analyze longitudinal data using the LMMs procedure in the SPSS statistical software package.

  14. Numerical identification procedure between a micro-Cauchy model and a macro-second gradient model for planar pantographic structures

    Science.gov (United States)

    Giorgio, Ivan

    2016-08-01

    In order to design the microstructure of metamaterials showing high toughness in extension (property to be shared with muscles), it has been recently proposed (Dell'Isola et al. in Z Angew Math Phys 66(6):3473-3498, 2015) to consider pantographic structures. It is possible to model such structures at a suitably small length scale (resolving in detail the interconnecting pivots/cylinders) using a standard Cauchy first gradient theory. However, the computational costs for such modelling choice are not allowing for the study of more complex mechanical systems including for instance many pantographic substructures. The microscopic model considered here is a quadratic isotropic Saint-Venant first gradient continuum including geometric nonlinearities and characterized by two Lamé parameters. The introduced macroscopic two-dimensional model for pantographic sheets is characterized by a deformation energy quadratic both in the first and second gradient of placement. However, as underlined in Dell'Isola et al. (Proc R Soc Lond A 472(2185):20150790, 2016), it is needed that the second gradient stiffness depends on the first gradient of placement if large deformations and large displacements configurations must be described. The numerical identification procedure presented in this paper consists in fitting the macro-constitutive parameters using several numerical simulations performed with the micro-model. The parameters obtained by the best fit identification in few deformation problems fit very well also in many others, showing that the reduced proposed model is suitable to get an effective model at relevantly lower computational effort. The presented numerical evidences suggest that a rigorous mathematical homogenization result most likely holds.

  15. Proposed core competencies and empirical validation procedure in competency modeling: confirmation and classification

    Directory of Open Access Journals (Sweden)

    Anna Katarzyna Baczynska

    2016-03-01

    Full Text Available Competency models provide insight into key skills which are common to many positions in an organization. Moreover, there is a range of competencies that is used by many companies. Researchers have developed core competency terminology to underline their cross-organizational value. The article presents a theoretical model of core competencies consisting of two main higher-order competencies called performance and entrepreneurship. Each of them consists of three elements: the performance competency includes cooperation, organization of work and goal orientation, while entrepreneurship includes innovativeness, calculated risk-taking and pro-activeness. However, there is lack of empirical validation of competency concepts in organizations and this would seem crucial for obtaining reliable results from organizational research. We propose a two-step empirical validation procedure: 1 confirmation factor analysis, and 2 classification of employees. The sample consisted of 636 respondents (M = 44.5; SD = 15.1. Participants were administered a questionnaire developed for the study purpose. The reliability, measured by Cronbach’s alpha, ranged from .60 to .83 for six scales. Next, we tested the model using a confirmatory factor analysis. The two separate, single models of performance and entrepreneurial orientations fit quite well to the data, while a complex model based on the two single concepts needs further research. In the classification of employees based on the two higher order competencies we obtained four main groups of employees. Their profiles relate to those found in the literature, including so-called niche finders and top performers. Some proposal for organizations is discussed.

  16. An incremental procedure model for e-learning projects at universities

    Directory of Open Access Journals (Sweden)

    Pahlke, Friedrich

    2006-11-01

    Full Text Available E-learning projects at universities are produced under different conditions than in industry. The main characteristic of many university projects is that these are realized quasi in a solo effort. In contrast, in private industry the different, interdisciplinary skills that are necessary for the development of e-learning are typically supplied by a multimedia agency.A specific procedure tailored for the use at universities is therefore required to facilitate mastering the amount and complexity of the tasks.In this paper an incremental procedure model is presented, which describes the proceeding in every phase of the project. It allows a high degree of flexibility and emphasizes the didactical concept – instead of the technical implementation. In the second part, we illustrate the practical use of the theoretical procedure model based on the project “Online training in Genetic Epidemiology”.

  17. Detection of Earthquake-Induced Damage in a Framed Structure Using a Finite Element Model Updating Procedure

    Science.gov (United States)

    Kim, Seung-Nam; Park, Taewon; Lee, Sang-Hyun

    2014-01-01

    Damage of a 5-story framed structure was identified from two types of measured data, which are frequency response functions (FRF) and natural frequencies, using a finite element (FE) model updating procedure. In this study, a procedure to determine the appropriate weightings for different groups of observations was proposed. In addition, a modified frame element which included rotational springs was used to construct the FE model for updating to represent concentrated damage at the member ends (a formulation for plastic hinges in framed structures subjected to strong earthquakes). The results of the model updating and subsequent damage detection when the rotational springs (RS model) were used were compared with those obtained using the conventional frame elements (FS model). Comparisons indicated that the RS model gave more accurate results than the FS model. That is, the errors in the natural frequencies of the updated models were smaller, and the identified damage showed clearer distinctions between damaged and undamaged members and was more consistent with observed damage. PMID:24574888

  18. Detection of Earthquake-Induced Damage in a Framed Structure Using a Finite Element Model Updating Procedure

    Directory of Open Access Journals (Sweden)

    Eunjong Yu

    2014-01-01

    Full Text Available Damage of a 5-story framed structure was identified from two types of measured data, which are frequency response functions (FRF and natural frequencies, using a finite element (FE model updating procedure. In this study, a procedure to determine the appropriate weightings for different groups of observations was proposed. In addition, a modified frame element which included rotational springs was used to construct the FE model for updating to represent concentrated damage at the member ends (a formulation for plastic hinges in framed structures subjected to strong earthquakes. The results of the model updating and subsequent damage detection when the rotational springs (RS model were used were compared with those obtained using the conventional frame elements (FS model. Comparisons indicated that the RS model gave more accurate results than the FS model. That is, the errors in the natural frequencies of the updated models were smaller, and the identified damage showed clearer distinctions between damaged and undamaged members and was more consistent with observed damage.

  19. Detection of earthquake-induced damage in a framed structure using a finite element model updating procedure.

    Science.gov (United States)

    Yu, Eunjong; Kim, Seung-Nam; Park, Taewon; Lee, Sang-Hyun

    2014-01-01

    Damage of a 5-story framed structure was identified from two types of measured data, which are frequency response functions (FRF) and natural frequencies, using a finite element (FE) model updating procedure. In this study, a procedure to determine the appropriate weightings for different groups of observations was proposed. In addition, a modified frame element which included rotational springs was used to construct the FE model for updating to represent concentrated damage at the member ends (a formulation for plastic hinges in framed structures subjected to strong earthquakes). The results of the model updating and subsequent damage detection when the rotational springs (RS model) were used were compared with those obtained using the conventional frame elements (FS model). Comparisons indicated that the RS model gave more accurate results than the FS model. That is, the errors in the natural frequencies of the updated models were smaller, and the identified damage showed clearer distinctions between damaged and undamaged members and was more consistent with observed damage.

  20. Exploring into the New Model Procedure in Translation: Wafting as a Case in Point

    Science.gov (United States)

    Akbari, Alireza

    2013-01-01

    Choosing the near equivalence for translator is of great concern nowadays. While it seems more commitment has been given to this issue, yet there are still rooms for more attention to innovative methods of Translation Studies in this direction. The idea of wafting procedure in Intermediacy model of translation comes from a book by Alireza Akbari…

  1. User Acceptance of YouTube for Procedural Learning: An Extension of the Technology Acceptance Model

    Science.gov (United States)

    Lee, Doo Young; Lehto, Mark R.

    2013-01-01

    The present study was framed using the Technology Acceptance Model (TAM) to identify determinants affecting behavioral intention to use YouTube. Most importantly, this research emphasizes the motives for using YouTube, which is notable given its extrinsic task goal of being used for procedural learning tasks. Our conceptual framework included two…

  2. The Psychology Department Model Advisement Procedure: A Comprehensive, Systematic Approach to Career Development Advisement

    Science.gov (United States)

    Howell-Carter, Marya; Nieman-Gonder, Jennifer; Pellegrino, Jennifer; Catapano, Brittani; Hutzel, Kimberly

    2016-01-01

    The MAP (Model Advisement Procedure) is a comprehensive, systematic approach to developmental student advisement. The MAP was implemented to improve advisement consistency, improve student preparation for internships/senior projects, increase career exploration, reduce career uncertainty, and, ultimately, improve student satisfaction with the…

  3. Conceptualizing and Testing Random Indirect Effects and Moderated Mediation in Multilevel Models: New Procedures and Recommendations

    Science.gov (United States)

    Bauer, Daniel J.; Preacher, Kristopher J.; Gil, Karen M.

    2006-01-01

    The authors propose new procedures for evaluating direct, indirect, and total effects in multilevel models when all relevant variables are measured at Level 1 and all effects are random. Formulas are provided for the mean and variance of the indirect and total effects and for the sampling variances of the average indirect and total effects.…

  4. A new experimental procedure for incorporation of model contaminants in polymer hosts

    NARCIS (Netherlands)

    Papaspyrides, C.D.; Voultzatis, Y.; Pavlidou, S.; Tsenoglou, C.; Dole, P.; Feigenbaum, A.; Paseiro, P.; Pastorelli, S.; Cruz Garcia, C. de la; Hankemeier, T.; Aucejo, S.

    2005-01-01

    A new experimental procedure for incorporation of model contaminants in polymers was developed as part of a general scheme for testing the efficiency of functional barriers in food packaging. The aim was to progressively pollute polymers in a controlled fashion up to a high level in the range of

  5. Evaluation of alternative surface runoff accounting procedures using the SWAT model

    Science.gov (United States)

    For surface runoff estimation in the Soil and Water Assessment Tool (SWAT) model, the curve number (CN) procedure is commonly adopted to calculate surface runoff by utilizing antecedent soil moisture condition (SCSI) in field. In the recent version of SWAT (SWAT2005), an alternative approach is ava...

  6. Silk Device for the Treatment of Intracranial Aneurysms. Part 1: Peri-Procedural Results, Technical Aspects and Learning Curve.

    Science.gov (United States)

    Gurkas, Erdem; Kaya, Tunca; Daglioglu, Ergun; Akmangit, Ilkay; Belen, Deniz; Peker, Ahmet; Dede, Dogan; Arat, Anil

    2016-01-01

    We evaluated the procedural outcomes of intracranial aneurysm treatment with the Silk device and its relation with operator experience. We also detailed some technical points we learned throughout our experience. One hundred and six consecutive patients with intracranial aneurysms treated using Silk (BaltExtrusion, Montmorency, France) stent between October 2010 and November 2013 were included. Patients were evaluated in terms of age, sex, aneurysm size, location, technical success, and adverse events. There were 106 patients (71 female) undergoing 116 procedures with a mean age of 49.8 (range: 3-78 years). Mean aneurysm size was 10.7±8.0 (range, 2-40 mm). Technical success of the procedures was 96.5%. Adverse event rate was 11.2%. Among adverse events, there were 4 adverse events without complications, 2 mild complications, 7 severe complications, 4 of which resulted with death. The adverse event rate was significantly higher during the first half of the operator's experience. The rate of adverse events seemed to stabilize after around 50 patients. Adverse events, regardless of the presence or absence of a clinical complication, were more frequent in aneurysms larger than 18.5 mm. Safety of flow-diverter (FD) placement for intracranial aneurysms increases with operator experience. Training programs in endovascular management of cerebrovascular diseases and relevant fellowship curricula must be adapted to include sufficient flow diverter experience. The learning curve needs to be kept in mind when studies comparing different FD devices or those comparing other treatments to FDS are planned.

  7. Procedural Generation of Large-Scale Forests Using a Graph-Based Neutral Landscape Model

    Directory of Open Access Journals (Sweden)

    Jiaqi Li

    2018-03-01

    Full Text Available Specifying the positions and attributes of plants (e.g., species, size, and height during the procedural generation of large-scale forests in virtual geographic environments is challenging, especially when reflecting the characteristics of vegetation distributions. To address this issue, a novel graph-based neutral landscape model (NLM is proposed to generate forest landscapes with varying compositions and configurations. Our model integrates a set of class-level landscape metrics and generates more realistic and variable landscapes compared with existing NLMs controlled by limited global-level landscape metrics. To produce patches with particular sizes and shapes, a region adjacency graph is transformed from a cluster map that is generated based upon percolation theory; subsequently, optimal neighboring nodes in the graph are merged under restricted growth conditions from a source node. The locations of seeds are randomly placed and their species are classified according to the generated forest landscapes to obtain the final tree distributions. The results demonstrate that our method can generate realistic vegetation distributions representing different spatial patterns of species with a time efficiency that satisfies the requirements for constructing large-scale virtual forests.

  8. Phoenix – A model-based Human Reliability Analysis methodology: Qualitative Analysis Procedure

    International Nuclear Information System (INIS)

    Ekanem, Nsimah J.; Mosleh, Ali; Shen, Song-Hua

    2016-01-01

    Phoenix method is an attempt to address various issues in the field of Human Reliability Analysis (HRA). Built on a cognitive human response model, Phoenix incorporates strong elements of current HRA good practices, leverages lessons learned from empirical studies, and takes advantage of the best features of existing and emerging HRA methods. Its original framework was introduced in previous publications. This paper reports on the completed methodology, summarizing the steps and techniques of its qualitative analysis phase. The methodology introduces the “Crew Response Tree” which provides a structure for capturing the context associated with Human Failure Events (HFEs), including errors of omission and commission. It also uses a team-centered version of the Information, Decision and Action cognitive model and “macro-cognitive” abstractions of crew behavior, as well as relevant findings from cognitive psychology literature and operating experience, to identify potential causes of failures and influencing factors during procedure-driven and knowledge-supported crew-plant interactions. The result is the set of identified HFEs and likely scenarios leading to each. The methodology itself is generic in the sense that it is compatible with various quantification methods, and can be adapted for use across different environments including nuclear, oil and gas, aerospace, aviation, and healthcare. - Highlights: • Produces a detailed, consistent, traceable, reproducible and properly documented HRA. • Uses “Crew Response Tree” to capture context associated with Human Failure Events. • Models dependencies between Human Failure Events and influencing factors. • Provides a human performance model for relating context to performance. • Provides a framework for relating Crew Failure Modes to its influencing factors.

  9. [Assessments of long-term results of different types of sling procedures for stress urinary incontinence in women].

    Science.gov (United States)

    Loran, O B; Seregin, A V; Dovlatov, Z A

    2016-02-01

    To evaluate long-term results of surgery for stress urinary incontinence in women using different types of sling procedures. The study included 698 patients aged 42 to 68 years (median 54 years) with stress urinary incontinence. TVT was used in 167 (23.9%) cases, TVT-O Gynecare system in 359 (51.4%), TVT-O Monarch system in 105 (15.0%), and TVT Secur mini-sling system - in 67 (9.6%). Follow-up ranged from 12 to 108 months (median 55 months). Patients' status was assessed using UDI-6 and IIQ-7 questionnaires, an improvised treatment satisfaction questionnaire, voiding diary, cough test and 1-hour Pad-test. The effectiveness of the treatment, according to objective criteria was 92.2%, 93.3%, 91.4% and 92.5% after surgery with TVT, TVT-O Gynecare, TVT-O Monarch and TVT Secur, respectively, and according to subjective criteria - 90.4%, 91.1%, 89.5% and 91.0%. No differences in the effectiveness of techniques were found. The data obtained in long-term observations of a large sample of patients treated with a variety of techniques in a single center showed the effectiveness and safety of modern sling procedures for correcting urinary incontinence in women.

  10. A Proposed Model for Selecting Measurement Procedures for the Assessment and Treatment of Problem Behavior.

    Science.gov (United States)

    LeBlanc, Linda A; Raetz, Paige B; Sellers, Tyra P; Carr, James E

    2016-03-01

    Practicing behavior analysts frequently assess and treat problem behavior as part of their ongoing job responsibilities. Effective measurement of problem behavior is critical to success in these activities because some measures of problem behavior provide more accurate and complete information about the behavior than others. However, not every measurement procedure is appropriate for every problem behavior and therapeutic circumstance. We summarize the most commonly used measurement procedures, describe the contexts for which they are most appropriate, and propose a clinical decision-making model for selecting measurement produces given certain features of the behavior and constraints of the therapeutic environment.

  11. Detection Procedure for a Single Additive Outlier and Innovational Outlier in a Bilinear Model

    Directory of Open Access Journals (Sweden)

    Azami Zaharim

    2007-01-01

    Full Text Available A single outlier detection procedure for data generated from BL(1,1,1,1 models is developed. It is carried out in three stages. Firstly, the measure of impact of an IO and AO denoted by IO ω , AO ω , respectively are derived based on least squares method. Secondly, test statistics and test criteria are defined for classifying an observation as an outlier of its respective type. Finally, a general single outlier detection procedure is presented to distinguish a particular type of outlier at a time point t.

  12. Some results regarding the comparison of the Earth's atmospheric models

    Directory of Open Access Journals (Sweden)

    Šegan S.

    2005-01-01

    Full Text Available In this paper we examine air densities derived from our realization of aeronomic atmosphere models based on accelerometer measurements from satellites in a low Earth's orbit (LEO. Using the adapted algorithms we derive comparison parameters. The first results concerning the adjustment of the aeronomic models to the total-density model are given.

  13. The radiation protection principles model as a tool in the e-waste procedures

    Energy Technology Data Exchange (ETDEWEB)

    Tsitomeneas, S. Th., E-mail: stsit@teipir.gr [Piraeus University of Applied Sciences, Aigaleo (Greece); Vourlias, K., E-mail: kvourlias@yahoo.gr [Aristotle University of Thessaloniki (Greece); Geronikolou, St. A., E-mail: sgeronik@bioacademy.gr [Biomedical Research Foundation Academy of Athens, Athens (Greece)

    2016-03-25

    The electrical and electronic waste (e-waste) management is a global environmental problem dominated by the precautionary principle application, resulted to preliminary and ambiguous potential adverse effects, of extensive scientific uncertainty. In order to overcome the detected stochastic effects confusions in this field, we propose the inclusion of the principles of justification-optimization-limitation and of prudent avoidance. This model is already, established in radiation protection, so that toxicity as a result of the e-waste management would decrease, whilst the precious metals would be saved. We, further, resolve the classification of rejected items as reusable or as waste, so that the procedure of dismantling and recycling becomes easier, and the collecting-transporting-placement at an e-waste landfill would be safer. In conclusion, our proposing pattern in the e-waste management enforces the sustainable reducing-reusing-recycling, saves time/money and advances safety by including more sources of e-waste (military, medical etc) that were excluded previously.

  14. Evaluation of relevant information for optimal reflector modeling through data assimilation procedures

    Directory of Open Access Journals (Sweden)

    Argaud Jean-Philippe

    2015-01-01

    Full Text Available The goal of this study is to look after the amount of information that is mandatory to get a relevant parameters optimisation by data assimilation for physical models in neutronic diffusion calculations, and to determine what is the best information to reach the optimum of accuracy at the cheapest cost. To evaluate the quality of the optimisation, we study the covariance matrix that represents the accuracy of the optimised parameter. This matrix is a classical output of the data assimilation procedure, and it is the main information about accuracy and sensitivity of the parameter optimal determination. From these studies, we present some results collected from the neutronic simulation of nuclear power plants. On the basis of the configuration studies, it has been shown that with data assimilation we can determine a global strategy to optimise the quality of the result with respect to the amount of information provided. The consequence of this is a cost reduction in terms of measurement and/or computing time with respect to the basic approach.

  15. The radiation protection principles model as a tool in the e-waste procedures

    International Nuclear Information System (INIS)

    Tsitomeneas, S. Th.; Vourlias, K.; Geronikolou, St. A.

    2016-01-01

    The electrical and electronic waste (e-waste) management is a global environmental problem dominated by the precautionary principle application, resulted to preliminary and ambiguous potential adverse effects, of extensive scientific uncertainty. In order to overcome the detected stochastic effects confusions in this field, we propose the inclusion of the principles of justification-optimization-limitation and of prudent avoidance. This model is already, established in radiation protection, so that toxicity as a result of the e-waste management would decrease, whilst the precious metals would be saved. We, further, resolve the classification of rejected items as reusable or as waste, so that the procedure of dismantling and recycling becomes easier, and the collecting-transporting-placement at an e-waste landfill would be safer. In conclusion, our proposing pattern in the e-waste management enforces the sustainable reducing-reusing-recycling, saves time/money and advances safety by including more sources of e-waste (military, medical etc) that were excluded previously.

  16. Minkowski momentum resulting from a vacuum-medium mapping procedure, and a brief review of Minkowski momentum experiments

    Science.gov (United States)

    Brevik, Iver

    2017-02-01

    A discussion is given on the interpretation and physical importance of the Minkowski momentum in macroscopic electrodynamics (essential for the Abraham-Minkowski problem). We focus on the following two facets: (1) Adopting a simple dielectric model where the refractive index n is constant, we demonstrate by means of a mapping procedure how the electromagnetic field in a medium can be mapped into a corresponding field in vacuum. This mapping was presented many years ago (Brevik and Lautrup, 1970), but is apparently not well known. A characteristic property of this procedure is that it shows how naturally the Minkowski energy-momentum tensor fits into the canonical formalism. Especially the spacelike character of the electromagnetic total four-momentum for a radiation field (implying negative electromagnetic energy in some inertial frames), so strikingly demonstrated in the Cherenkov effect, is worth attention. (2) Our second objective is to give a critical analysis of some recent experiments on electromagnetic momentum. Care must here be taken in the interpretations: it is easy to be misled and conclude that an experiment is important for the energy-momentum problem, while what is demonstrated experimentally is merely the action of the Abraham-Minkowski force acting in surface layers or inhomogeneous regions. The Abraham-Minkowski force is common for the two energy-momentum tensors and carries no information about field momentum. As a final item, we propose an experiment that might show the existence of the Abraham force at high frequencies. This would eventually be a welcome optical analogue to the classic low-frequency 1975 Lahoz-Walker experiment.

  17. Calibration procedure for a potato crop growth model using information from across Europe

    DEFF Research Database (Denmark)

    Heidmann, Tove; Tofteng, Charlotte; Abrahamsen, Per

    2008-01-01

    In the FertOrgaNic EU project, 3 years of field experiments with drip irrigation and fertigation were carried out at six different sites across Europe, involving seven different varieties of potato. The Daisy model, which simulates plant growth together with water and nitrogen dynamics, was used...... to simulate the field experiments. An initial potato parameterisation was generated from an independent dataset and was used for site-specific calibrations. At those sites where the same variety was used for all 3 years, the calibration of the initial potato model was based on the first 2 years using the last...... for adaptation of the Daisy model to new potato varieties or for the improvement of the existing parameter set. The procedure is then, as a starting point, to focus the calibration process on the recommended list of parameters to change. We demonstrate this approach by showing the procedure for recalibrating...

  18. Longitudinal data analyses using linear mixed models in SPSS: concepts, procedures and illustrations.

    Science.gov (United States)

    Shek, Daniel T L; Ma, Cecilia M S

    2011-01-05

    Although different methods are available for the analyses of longitudinal data, analyses based on generalized linear models (GLM) are criticized as violating the assumption of independence of observations. Alternatively, linear mixed models (LMM) are commonly used to understand changes in human behavior over time. In this paper, the basic concepts surrounding LMM (or hierarchical linear models) are outlined. Although SPSS is a statistical analyses package commonly used by researchers, documentation on LMM procedures in SPSS is not thorough or user friendly. With reference to this limitation, the related procedures for performing analyses based on LMM in SPSS are described. To demonstrate the application of LMM analyses in SPSS, findings based on six waves of data collected in the Project P.A.T.H.S. (Positive Adolescent Training through Holistic Social Programmes) in Hong Kong are presented.

  19. Accounting for intracell flow in models with emphasis on water table recharge and stream-aquifer interaction: 2. A procedure

    Science.gov (United States)

    Jorgensen, Donald G.; Signor, Donald C.; Imes, Jeffrey L.

    1989-01-01

    Intercepted intracell flow, especially if cell includes water table recharge and a stream ((sink), can result in significant model error if not accounted for. A procedure utilizing net flow per cell (Fn) that accounts for intercepted intracell flow can be used for both steady state and transient simulations. Germane to the procedure is the determination of the ratio of area of influence of the interior sink to the area of the cell (Ai/Ac). Ai is the area in which water table recharge has the potential to be intercepted by the sink. Determining Ai/Ac requires either a detailed water table map or observation of stream conditions within the cell. A proportioning parameter M, which is equal to 1 or slightly less and is a function of cell geometry, is used to determine how much of the water that has potential for interception is intercepted by the sink within the cell. Also germane to the procedure is the determination of the flow across the streambed (Fs), which is not directly a function of cell size, due to difference in head between the water level in the stream and the potentiometric surface of the aquifer underlying the streambed. The use of Fn for steady state simulations allows simulation of water levels without utilizing head-dependent or constant head boundary conditions which tend to constrain the model-calculated water levels, an undesirable result if a comparison of measured and calculated water levels is being made. Transient simulations of streams usually utilize a head-dependent boundary condition and a leakance value to model a stream. Leakance values for each model cell can be determined from a steady state simulation, which used the net flow per cell procedure. For transient simulation, Fn would not include Fs. Also, for transient simulation it is necessary to check Fn at different time intervals because M and Ai/Ac are not constant and change with time. The procedure was used successfully in two different models of the aquifer system

  20. Verification of aseismic design model by using experimental results

    International Nuclear Information System (INIS)

    Mizuno, N.; Sugiyama, N.; Suzuki, T.; Shibata, Y.; Miura, K.; Miyagawa, N.

    1985-01-01

    A lattice model is applied as an analysis model for an aseismic design of the Hamaoka nuclear reactor building. With object to verify an availability of this design model, two reinforced concrete blocks are constructed on the ground and the forced vibration tests are carried out. The test results are well followed by simulation analysis using the lattice model. Damping value of the ground obtained from the test is more conservative than the design value. (orig.)

  1. Acid-base properties of the alumina surface: influence of the titration procedures on the microcalorimetric results.

    Science.gov (United States)

    Morel, Jean-Pierre; Marmier, Nicolas; Hurel, Charlotte; Morel-Desrosiers, Nicole

    2009-10-01

    The enthalpy changes associated with the protonation and deprotonation of an alumina surface have been determined on the basis of microcalorimetry experiments and acid-base potentiometric titrations at 25 degrees C. It has been shown that the results may vary significantly according to the experimental procedure. In order to do so, the potentiometric and microcalorimetric titrations have been carried out first from an acidic pH to basic pH and second from a pH near the pH(zpc) of alumina to acidic or basic pH. It has been demonstrated that the pK(a) values deduced from the potentiometric titrations are the same whatever the experimental protocol whereas the only way to obtain meaningful enthalpies of proton exchange is to carry out microcalorimetric titrations by starting around the point of zero charge.

  2. Indications for and clinical procedures resulting from magnetic resonance imaging of the knee in older patients: Are we choosing wisely?

    Science.gov (United States)

    Parent, Marc-Etienne; Vézina, François; Carrier, Nathalie; Masetto, Ariel

    2018-03-01

    To analyze the indications for and clinical procedures resulting from knee magnetic resonance imaging (MRI) in older patients. We retrospectively analyzed 215 medical records of patients 50 years of age and older who had undergone a unilateral knee MRI in 2009. Centre hospitalier universitaire de Sherbrooke in Quebec. Patients 50 years of age and older who underwent a knee MRI in 2009. The main outcome measure was an invasive procedure in the same knee that underwent an MRI. Medical charts were reviewed up to 2014 for patient characteristics, MRI indication, ordering physician specialty, radiography before MRI, MRI findings, and clinical procedures resulting from the MRI. The patients' mean (SD) age was 60.6 (7.5) years. The main MRI indications were meniscopathy (148 [68.8%]) and chronic pain (92 [42.8%]). The main MRI findings were osteoarthritis (OA) (185 [86.0%]) and meniscal lesions (170 [79.1%]). Only 82 (38.1%) patients had a plain radiograph in the 24 months preceding the MRI, usually without a standing anteroposterior view. Findings on pre-MRI radiography (n = 201) demonstrated OA in 144 (71.6%) patients. Overall, 87 (40.5%) patients were seen by an orthopedic surgeon and 27 (31.0%) of these patients underwent an invasive intervention. Among the 81 patients with moderate to severe OA on MRI, 36 (44.4%) had radiographic evidence of moderate to severe OA and only 3 (3.7%) underwent arthroscopic meniscectomy. Our study reproduces the known association between OA and degenerative meniscal changes in older patients. We have found a surprising underuse of the standing anteroposterior view on radiography. Most patients in our cohort could have been appropriately diagnosed and treated based on such radiographic information, as demonstrated by pre-MRI findings, thus avoiding the MRI and subsequent evaluation by an orthopedic surgeon. Meniscectomy was rarely performed, particularly in patients with advanced OA. Educational and pragmatic measures must be emphasized

  3. VALIDATION TESTS OF OPEN-SOURCE PROCEDURES FOR DIGITAL CAMERA CALIBRATION AND 3D IMAGE-BASED MODELLING

    Directory of Open Access Journals (Sweden)

    I. Toschi

    2013-07-01

    Full Text Available Among the many open-source software solutions recently developed for the extraction of point clouds from a set of un-oriented images, the photogrammetric tools Apero and MicMac (IGN, Institut Géographique National aim to distinguish themselves by focusing on the accuracy and the metric content of the final result. This paper firstly aims at assessing the accuracy of the simplified and automated calibration procedure offered by the IGN tools. Results obtained with this procedure were compared with those achieved with a test-range calibration approach using a pre-surveyed laboratory test-field. Both direct and a-posteriori validation tests turned out successfully showing the stability and the metric accuracy of the process, even when low textured or reflective surfaces are present in the 3D scene. Afterwards, the possibility of achieving accurate 3D models from the subsequently extracted dense point clouds is also evaluated. Three different types of sculptural elements were chosen as test-objects and "ground-truth" data were acquired with triangulation laser scanners. 3D models derived from point clouds oriented with a simplified relative procedure show a suitable metric accuracy: all comparisons delivered a standard deviation of millimeter-level. The use of Ground Control Points in the orientation phase did not improve significantly the accuracy of the final 3D model, when a small figure-like corbel was used as test-object.

  4. CANFIS: A non-linear regression procedure to produce statistical air-quality forecast models

    Energy Technology Data Exchange (ETDEWEB)

    Burrows, W.R.; Montpetit, J. [Environment Canada, Downsview, Ontario (Canada). Meteorological Research Branch; Pudykiewicz, J. [Environment Canada, Dorval, Quebec (Canada)

    1997-12-31

    Statistical models for forecasts of environmental variables can provide a good trade-off between significance and precision in return for substantial saving of computer execution time. Recent non-linear regression techniques give significantly increased accuracy compared to traditional linear regression methods. Two are Classification and Regression Trees (CART) and the Neuro-Fuzzy Inference System (NFIS). Both can model predict and distributions, including the tails, with much better accuracy than linear regression. Given a learning data set of matched predict and predictors, CART regression produces a non-linear, tree-based, piecewise-continuous model of the predict and data. Its variance-minimizing procedure optimizes the task of predictor selection, often greatly reducing initial data dimensionality. NFIS reduces dimensionality by a procedure known as subtractive clustering but it does not of itself eliminate predictors. Over-lapping coverage in predictor space is enhanced by NFIS with a Gaussian membership function for each cluster component. Coefficients for a continuous response model based on the fuzzified cluster centers are obtained by a least-squares estimation procedure. CANFIS is a two-stage data-modeling technique that combines the strength of CART to optimize the process of selecting predictors from a large pool of potential predictors with the modeling strength of NFIS. A CANFIS model requires negligible computer time to run. CANFIS models for ground-level O{sub 3}, particulates, and other pollutants will be produced for each of about 100 Canadian sites. The air-quality models will run twice daily using a small number of predictors isolated from a large pool of upstream and local Lagrangian potential predictors.

  5. 49 CFR 40.209 - What procedural problems do not result in the cancellation of a test and do not require correction?

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false What procedural problems do not result in the cancellation of a test and do not require correction? 40.209 Section 40.209 Transportation Office of the... Problems in Drug Tests § 40.209 What procedural problems do not result in the cancellation of a test and do...

  6. Measuring the Effects of Customs and Administrative Procedures on Trade: Gravity Model for South-Eastern Europe

    Directory of Open Access Journals (Sweden)

    Katerina Toševska-Trpčevska

    2014-04-01

    Full Text Available This paper measures the effects of certain customs and administrative procedures on trade between the countries of South-Eastern Europe in the period 2008-2012. Following OECD methodology, we employ the augmented gravity model. The empirical results suggest that the number of days spent at the border and costs paid in both importer and exporter countries had significant negative influence on the volume of trade in the period 2008-2012. In addition, the model underlines that sharing the same border and being part of the former Yugoslav market are important determinants of trade in the region.

  7. Steel Containment Vessel Model Test: Results and Evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Costello, J.F.; Hashimote, T.; Hessheimer, M.F.; Luk, V.K.

    1999-03-01

    A high pressure test of the steel containment vessel (SCV) model was conducted on December 11-12, 1996 at Sandia National Laboratories, Albuquerque, NM, USA. The test model is a mixed-scaled model (1:10 in geometry and 1:4 in shell thickness) of an improved Mark II boiling water reactor (BWR) containment. A concentric steel contact structure (CS), installed over the SCV model and separated at a nominally uniform distance from it, provided a simplified representation of a reactor shield building in the actual plant. The SCV model and contact structure were instrumented with strain gages and displacement transducers to record the deformation behavior of the SCV model during the high pressure test. This paper summarizes the conduct and the results of the high pressure test and discusses the posttest metallurgical evaluation results on specimens removed from the SCV model.

  8. Semantic Modeling of Administrative Procedures from a Spanish Regional Public Administration

    Directory of Open Access Journals (Sweden)

    Francisco José Hidalgo López

    2018-02-01

    Full Text Available Over the past few years, Public Administrations have been providing systems for procedures and files electronic processing to ensure compliance with regulations and provide public services to citizens. Although each administration provides similar services to their citizens, these systems usually differ from the internal information management point of view since they usually come from different products and manufacturers. The common framework that regulations demand, and that Public Administrations must respect when processing electronic files, provides a unique opportunity for the development of intelligent agents in the field of administrative processes. However, for this development to be truly effective and applicable to the public sector, it is necessary to have a common representation model for these administrative processes. Although a lot of work has already been done in the development of public information reuse initiatives and common vocabularies standardization, this has not been carried out at the processes level. In this paper, we propose a semantic representation model of both processes models and processes for Public Administrations: the procedures and administrative files. The goal is to improve public administration open data initiatives and help to develop their sustainability policies, such as improving decision-making procedures and administrative management sustainability. As a case study, we modelled public administrative processes and files in collaboration with a Regional Public Administration in Spain, the Principality of Asturias, which enabled access to its information systems, helping the evaluation of our approach.

  9. Procedure to Determine Thermal Characteristics and Groundwater Influence in Heterogeneous Subsoil by an Enhanced Thermal Response Test and Numerical Modeling

    Science.gov (United States)

    Aranzabal, Nordin; Martos, Julio; Montero, Álvaro; Monreal, Llúcia; Soret, Jesús; Torres, José; García-Olcina, Raimundo

    2016-04-01

    Ground thermal conductivity and borehole thermal resistance are indispensable parameters for the optimal design of subsoil thermal processes and energy storage characterization. The standard method to determine these parameters is the Thermal Response Test (TRT) which results are evaluated by models considering the ground being homogeneous and isotropic. This method obtains an effective ground thermal conductivity which represents an average of the thermal conductivity along the different layers crossed by perforation. In order to obtain a ground thermal conductivity profile as a function of depth two additional key factors are required, first, a new significant data set: a temperature profile along the borehole; and second, a new analysis procedure to extract ground heterogeneity from the recorded data. This research work presents the results of an analysis procedure, complementing the standard TRT analysis, which allows to estimate the thermal conductivity profile from a temperature profile measured along the borehole during a TRT. In the analysis procedure, a 3D Finite Element Model (FEM) is used to fit simulation results with experimental data, by a set of iterative simulations. This methodology is applied to a data set obtained throughout a TRT of 1kW heat power injection in a 30m depth Borehole Heat Exchange (BHE) facility. A highly conductive layer have been detected and located at 25 m depth. In addition, a novel automated device to obtain temperature profiles along geothermal pipes with or without fluid flow is presented. This sensor system is intended to improve the standard TRT and it allows the collection of depth depending thermal characteristics of the subsoil geological structure. Currently, some studies are being conducted in double U-pipe borehole installations in order to improve previously introduced analysis procedure. From a numerical model simulation that takes into account advective effects is pretended to estimate underground water velocity

  10. Demographic, procedural and 30-day safety results from the WEB Intra-saccular Therapy Study (WEB-IT).

    Science.gov (United States)

    Fiorella, David; Molyneux, Andrew; Coon, Alexander; Szikora, Istvan; Saatci, Isil; Baltacioglu, Feyyaz; Sultan, Ali; Arthur, Adam

    2017-12-01

    at 30 days), five (2.7%) transient ischemic attacks, and two (1.3%) minor subarachnoid hemorrhages, which did not meet the prospectively established criteria for PSEs. The WEB device can be used to treat WNBAs with a high level of procedural safety and a high degree of technical success. NCT02191618; Pre-results. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  11. Identifiability Results for Several Classes of Linear Compartment Models.

    Science.gov (United States)

    Meshkat, Nicolette; Sullivant, Seth; Eisenberg, Marisa

    2015-08-01

    Identifiability concerns finding which unknown parameters of a model can be estimated, uniquely or otherwise, from given input-output data. If some subset of the parameters of a model cannot be determined given input-output data, then we say the model is unidentifiable. In this work, we study linear compartment models, which are a class of biological models commonly used in pharmacokinetics, physiology, and ecology. In past work, we used commutative algebra and graph theory to identify a class of linear compartment models that we call identifiable cycle models, which are unidentifiable but have the simplest possible identifiable functions (so-called monomial cycles). Here we show how to modify identifiable cycle models by adding inputs, adding outputs, or removing leaks, in such a way that we obtain an identifiable model. We also prove a constructive result on how to combine identifiable models, each corresponding to strongly connected graphs, into a larger identifiable model. We apply these theoretical results to several real-world biological models from physiology, cell biology, and ecology.

  12. Quantitative modeling of the accuracy in registering preoperative patient-specific anatomic models into left atrial cardiac ablation procedures

    Energy Technology Data Exchange (ETDEWEB)

    Rettmann, Maryam E., E-mail: rettmann.maryam@mayo.edu; Holmes, David R.; Camp, Jon J.; Cameron, Bruce M.; Robb, Richard A. [Biomedical Imaging Resource, Mayo Clinic College of Medicine, Rochester, Minnesota 55905 (United States); Kwartowitz, David M. [Department of Bioengineering, Clemson University, Clemson, South Carolina 29634 (United States); Gunawan, Mia [Department of Biochemistry and Molecular and Cellular Biology, Georgetown University, Washington D.C. 20057 (United States); Johnson, Susan B.; Packer, Douglas L. [Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota 55905 (United States); Dalegrave, Charles [Clinical Cardiac Electrophysiology, Cardiology Division Hospital Sao Paulo, Federal University of Sao Paulo, 04024-002 Brazil (Brazil); Kolasa, Mark W. [David Grant Medical Center, Fairfield, California 94535 (United States)

    2014-02-15

    Purpose: In cardiac ablation therapy, accurate anatomic guidance is necessary to create effective tissue lesions for elimination of left atrial fibrillation. While fluoroscopy, ultrasound, and electroanatomic maps are important guidance tools, they lack information regarding detailed patient anatomy which can be obtained from high resolution imaging techniques. For this reason, there has been significant effort in incorporating detailed, patient-specific models generated from preoperative imaging datasets into the procedure. Both clinical and animal studies have investigated registration and targeting accuracy when using preoperative models; however, the effect of various error sources on registration accuracy has not been quantitatively evaluated. Methods: Data from phantom, canine, and patient studies are used to model and evaluate registration accuracy. In the phantom studies, data are collected using a magnetically tracked catheter on a static phantom model. Monte Carlo simulation studies were run to evaluate both baseline errors as well as the effect of different sources of error that would be present in a dynamicin vivo setting. Error is simulated by varying the variance parameters on the landmark fiducial, physical target, and surface point locations in the phantom simulation studies. In vivo validation studies were undertaken in six canines in which metal clips were placed in the left atrium to serve as ground truth points. A small clinical evaluation was completed in three patients. Landmark-based and combined landmark and surface-based registration algorithms were evaluated in all studies. In the phantom and canine studies, both target registration error and point-to-surface error are used to assess accuracy. In the patient studies, no ground truth is available and registration accuracy is quantified using point-to-surface error only. Results: The phantom simulation studies demonstrated that combined landmark and surface-based registration improved

  13. Evaluation of the behavioral characteristics of the mdx mouse model of duchenne muscular dystrophy through operant conditioning procedures.

    Science.gov (United States)

    Lewon, Matthew; Peters, Christina M; Van Ry, Pam M; Burkin, Dean J; Hunter, Kenneth W; Hayes, Linda J

    2017-09-01

    The mdx mouse is an important nonhuman model for Duchenne muscular dystrophy (DMD) research. Characterizing the behavioral traits of the strain relative to congenic wild-type (WT) mice may enhance our understanding of the cognitive deficits observed in some humans with DMD and contribute to treatment development and evaluation. In this paper we report the results of a number of experiments comparing the behavior of mdx to WT mice in operant conditioning procedures designed to assess learning and memory. We found that mdx outperformed WT in all learning and memory tasks involving food reinforcement, and this appeared to be related to the differential effects of the food deprivation motivating operation on mdx mice. Conversely, WT outperformed mdx in an escape/avoidance learning task. These results suggest motivational differences between the strains and demonstrate the potential utility of operant conditioning procedures in the assessment of the behavioral characteristics of the mdx mouse. Copyright © 2017 Elsevier B.V. All rights reserved.

  14. A Perspective On Procedural Modeling Based On Structural Analysis = Una perspectiva sobre modelado procedural basado en analisis estructurales

    OpenAIRE

    Fita, Josep Lluís; Besuievsky, Gonzalo; Patow, Gustavo

    2017-01-01

    Con el creciente aumento de las capacidades computacionales, el análisis estructural se ha convertido en una herramienta clave para la evaluación del estudio y conservación de edificios antiguos por parte de los historiadores del arte, curadores y otros especialistas. Por otro lado, el floreciente campo del modelado procedural ha proporcionado avances interesantes para la reconstrucción de edificios y estructuras urbanas no accesibles. Sin embargo, h...

  15. Results of the Marine Ice Sheet Model Intercomparison Project, MISMIP

    Directory of Open Access Journals (Sweden)

    F. Pattyn

    2012-05-01

    Full Text Available Predictions of marine ice-sheet behaviour require models that are able to robustly simulate grounding line migration. We present results of an intercomparison exercise for marine ice-sheet models. Verification is effected by comparison with approximate analytical solutions for flux across the grounding line using simplified geometrical configurations (no lateral variations, no effects of lateral buttressing. Unique steady state grounding line positions exist for ice sheets on a downward sloping bed, while hysteresis occurs across an overdeepened bed, and stable steady state grounding line positions only occur on the downward-sloping sections. Models based on the shallow ice approximation, which does not resolve extensional stresses, do not reproduce the approximate analytical results unless appropriate parameterizations for ice flux are imposed at the grounding line. For extensional-stress resolving "shelfy stream" models, differences between model results were mainly due to the choice of spatial discretization. Moving grid methods were found to be the most accurate at capturing grounding line evolution, since they track the grounding line explicitly. Adaptive mesh refinement can further improve accuracy, including fixed grid models that generally perform poorly at coarse resolution. Fixed grid models, with nested grid representations of the grounding line, are able to generate accurate steady state positions, but can be inaccurate over transients. Only one full-Stokes model was included in the intercomparison, and consequently the accuracy of shelfy stream models as approximations of full-Stokes models remains to be determined in detail, especially during transients.

  16. The effect of major adverse renal cardiovascular event (MARCE) incidence, procedure volume, and unit cost on the hospital savings resulting from contrast media use in inpatient angioplasty.

    Science.gov (United States)

    Keuffel, Eric; McCullough, Peter A; Todoran, Thomas M; Brilakis, Emmanouil S; Palli, Swetha R; Ryan, Michael P; Gunnarsson, Candace

    2018-04-01

    To determine the net economic impact of switching from low-osmolar contrast media (LOCM) to iso-osmolar contrast media (IOCM; iodixanol) in patients undergoing inpatient coronary or peripheral angioplasty in the United States (US). A budget impact model (BIM) was developed from a hospital perspective. Nationally representative procedural and contrast media prevalence rates, along with MARCE (major adverse renal cardiovascular event) incidence and episode-related cost data were derived from Premier Hospital Data (October 2014 to September 2015). A previously estimated relative risk reduction in MARCE associated with IOCM usage (9.3%) was applied. The higher cost of IOCM was included when calculating the net impact estimates at the aggregate, hospital type, and per hospital levels. One-way (±25%) and probabilistic sensitivity analyses identified the model's most important inputs. Based on weighted analysis, 513,882 US inpatient angioplasties and 35,610 MARCE cases were estimated annually. Switching to an "IOCM only" strategy from a "LOCM only" strategy increases contrast media cost, but prevents 2,900 MARCE events. The annual budget impact was an estimated saving of $30.71 million, aggregated across all US hospitals, $6,316 per hospital, or $60 per procedure. Net savings were maintained across all univariate sensitivity analyses. While MARCE/event-free cost differential was the most important factor driving total net savings for hospitals in the Northeast and West, procedural volume was important in the Midwest and rural locations. Switching to an "IOCM only" strategy from a "LOCM only" approach yields substantial net global savings to hospitals, both at the national level and within hospital sub-groups. Hospital administrators should maintain awareness of the factors that are likely to be more influential for their hospital and recognize that purchasing on the basis of lower contrast media cost may result in higher overall costs for patients undergoing inpatient

  17. Interpretation of surface water monitoring results in the authorisation procedure of plant protection products in the Netherlands

    NARCIS (Netherlands)

    Werd, de H.A.E.; Kruijne, R.

    2013-01-01

    As part of the ‘Surface Waters Decision Tree’ project a new authorisation procedure for plant protection products (PPPs) has been developed. One element is a procedure for feedback of monitoring data to the authorisation holder and the PPP authorisation authority. This report describes the

  18. Results on the symmetries of integrable fermionic models on chains

    International Nuclear Information System (INIS)

    Dolcini, F.; Montorsi, A.

    2001-01-01

    We investigate integrable fermionic models within the scheme of the graded quantum inverse scattering method, and prove that any symmetry imposed on the solution of the Yang-Baxter equation reflects on the constants of motion of the model; generalizations with respect to known results are discussed. This theorem is shown to be very effective when combined with the polynomial R-matrix technique (PRT): we apply both of them to the study of the extended Hubbard models, for which we find all the subcases enjoying several kinds of (super)symmetries. In particular, we derive a geometrical construction expressing any gl(2,1)-invariant model as a linear combination of EKS and U-supersymmetric models. Further, we use the PRT to obtain 32 integrable so(4)-invariant models. By joint use of the Sutherland's species technique and η-pairs construction we propose a general method to derive their physical features, and we provide some explicit results

  19. [DESCRIPTION AND PRESENTATION OF THE RESULTS OF ELECTROENCEPHALOGRAM PROCESSING USING AN INFORMATION MODEL].

    Science.gov (United States)

    Myznikov, I L; Nabokov, N L; Rogovanov, D Yu; Khankevich, Yu R

    2016-01-01

    The paper proposes to apply the informational modeling of correlation matrix developed by I.L. Myznikov in early 1990s in neurophysiological investigations, such as electroencephalogram recording and analysis, coherence description of signals from electrodes on the head surface. The authors demonstrate information models built using the data from studies of inert gas inhalation by healthy human subjects. In the opinion of the authors, information models provide an opportunity to describe physiological processes with a high level of generalization. The procedure of presenting the EEG results holds great promise for the broad application.

  20. Prediction of Placental Barrier Permeability: A Model Based on Partial Least Squares Variable Selection Procedure

    Directory of Open Access Journals (Sweden)

    Yong-Hong Zhang

    2015-05-01

    Full Text Available Assessing the human placental barrier permeability of drugs is very important to guarantee drug safety during pregnancy. Quantitative structure–activity relationship (QSAR method was used as an effective assessing tool for the placental transfer study of drugs, while in vitro human placental perfusion is the most widely used method. In this study, the partial least squares (PLS variable selection and modeling procedure was used to pick out optimal descriptors from a pool of 620 descriptors of 65 compounds and to simultaneously develop a QSAR model between the descriptors and the placental barrier permeability expressed by the clearance indices (CI. The model was subjected to internal validation by cross-validation and y-randomization and to external validation by predicting CI values of 19 compounds. It was shown that the model developed is robust and has a good predictive potential (r2 = 0.9064, RMSE = 0.09, q2 = 0.7323, rp2 = 0.7656, RMSP = 0.14. The mechanistic interpretation of the final model was given by the high variable importance in projection values of descriptors. Using PLS procedure, we can rapidly and effectively select optimal descriptors and thus construct a model with good stability and predictability. This analysis can provide an effective tool for the high-throughput screening of the placental barrier permeability of drugs.

  1. Design reinforced concrete structures: Differences in procedure, formula, and results between Eurocode 2 and British Standard 8110

    Science.gov (United States)

    Rahim, Mustaqqim Abdul; Ying, Lum Chui; Shahidan, Shahiron; Ghazaly, Zuhayr Md.; Anudai, Shamilah; Bawadi, Nor Faizah; Isa, Nur Fitriah; Hassan, Zulkarnain; Habulat, Afifuddin; Ismail, Zul-Atfi

    2017-09-01

    This research is mainly about comparisons of reinforced concrete structure design based on Eurocode 2 and British Standard 8110. The reinforcement concrete element is designed by referring Eurocode 2 (EN1992-1-1) and British Standard 8110 (BS8110-1:1997) for comparing purpose. The work examples of the structural elements has been done in this research to obtain the area of reinforcement required. The differences in procedure, formula and result of area of steel required for the elements based on both of the codes are compared and tabulated. In this research, there are five part of reinforced concrete structure elements are designed which are continuous beams, one way slabs, braced and short column, pile cap, and cantilever retaining wall. From the result acquired, it shows that area of reinforcement required based on EC 2 is lesser than BS 8110 and the dimension required based on BS8110 is larger than EC 2. Meanwhile, the design based on Eurocode 2 came out with more economical structural elements compare to BS 8110 as lesser steel and concrete volume required.

  2. A Numerical Procedure for Model Identifiability Analysis Applied to Enzyme Kinetics

    DEFF Research Database (Denmark)

    Daele, Timothy, Van; Van Hoey, Stijn; Gernaey, Krist

    2015-01-01

    The proper calibration of models describing enzyme kinetics can be quite challenging. In the literature, different procedures are available to calibrate these enzymatic models in an efficient way. However, in most cases the model structure is already decided on prior to the actual calibration...... and Pronzato (1997) and which can be easily set up for any type of model. In this paper the proposed approach is applied to the forward reaction rate of the enzyme kinetics proposed by Shin and Kim(1998). Structural identifiability analysis showed that no local structural model problems were occurring......) identifiability problems. By using the presented approach it is possible to detect potential identifiability problems and avoid pointless calibration (and experimental!) effort....

  3. Implications of the Declarative/Procedural Model for Improving Second Language Learning: The Role of Memory Enhancement Techniques

    Science.gov (United States)

    Ullman, Michael T.; Lovelett, Jarrett T.

    2018-01-01

    The declarative/procedural (DP) model posits that the learning, storage, and use of language critically depend on two learning and memory systems in the brain: declarative memory and procedural memory. Thus, on the basis of independent research on the memory systems, the model can generate specific and often novel predictions for language. Till…

  4. Quantitative modeling of the accuracy in registering preoperative patient-specific anatomic models into left atrial cardiac ablation procedures.

    Science.gov (United States)

    Rettmann, Maryam E; Holmes, David R; Kwartowitz, David M; Gunawan, Mia; Johnson, Susan B; Camp, Jon J; Cameron, Bruce M; Dalegrave, Charles; Kolasa, Mark W; Packer, Douglas L; Robb, Richard A

    2014-02-01

    In cardiac ablation therapy, accurate anatomic guidance is necessary to create effective tissue lesions for elimination of left atrial fibrillation. While fluoroscopy, ultrasound, and electroanatomic maps are important guidance tools, they lack information regarding detailed patient anatomy which can be obtained from high resolution imaging techniques. For this reason, there has been significant effort in incorporating detailed, patient-specific models generated from preoperative imaging datasets into the procedure. Both clinical and animal studies have investigated registration and targeting accuracy when using preoperative models; however, the effect of various error sources on registration accuracy has not been quantitatively evaluated. Data from phantom, canine, and patient studies are used to model and evaluate registration accuracy. In the phantom studies, data are collected using a magnetically tracked catheter on a static phantom model. Monte Carlo simulation studies were run to evaluate both baseline errors as well as the effect of different sources of error that would be present in a dynamic in vivo setting. Error is simulated by varying the variance parameters on the landmark fiducial, physical target, and surface point locations in the phantom simulation studies. In vivo validation studies were undertaken in six canines in which metal clips were placed in the left atrium to serve as ground truth points. A small clinical evaluation was completed in three patients. Landmark-based and combined landmark and surface-based registration algorithms were evaluated in all studies. In the phantom and canine studies, both target registration error and point-to-surface error are used to assess accuracy. In the patient studies, no ground truth is available and registration accuracy is quantified using point-to-surface error only. The phantom simulation studies demonstrated that combined landmark and surface-based registration improved landmark-only registration

  5. SModelS: A Tool for Making Systematic Use of Simplified Models Results

    Science.gov (United States)

    Waltenberger, Wolfgang; SModelS Group

    2016-10-01

    We present an automated software tool ”SModelS” to systematically confront theories Beyond the Standard Model (BSM) with experimental data. The tool consists of a general procedure to decompose such BSM theories into their Simplified Models Spectra (SMS). In addition, SModelS features a database containing the majority of the published SMS results of CMS and ATLAS. These results consist of the 95% confidence level upper limits on signal production cross sections. The two components together allow us to quickly confront any BSM model with LHC results. As a show-case example we will briefly discuss an application of our procedure to a specific supersymmetric model. It is one of our ongoing efforts to extend the framework to include also efficiency maps produced either by the experimental collaborations, by efforts performed within the phenomenological groups, or possibly also by ourselves. While the current implementation can handle null results only, it is our ultimate goal to build the Next Standard Model in a bottom-up fashion from both negative and positive results of several experiments. The implementation is open source, written in python, and available from http://smodels.hephy.at.

  6. Revision Arthroscopic Repair Versus Latarjet Procedure in Patients With Recurrent Instability After Initial Repair Attempt: A Cost-Effectiveness Model.

    Science.gov (United States)

    Makhni, Eric C; Lamba, Nayan; Swart, Eric; Steinhaus, Michael E; Ahmad, Christopher S; Romeo, Anthony A; Verma, Nikhil N

    2016-09-01

    To compare the cost-effectiveness of arthroscopic revision instability repair and Latarjet procedure in treating patients with recurrent instability after initial arthroscopic instability repair. An expected-value decision analysis of revision arthroscopic instability repair compared with Latarjet procedure for recurrent instability followed by failed repair attempt was modeled. Inputs regarding procedure cost, clinical outcomes, and health utilities were derived from the literature. Compared with revision arthroscopic repair, Latarjet was less expensive ($13,672 v $15,287) with improved clinical outcomes (43.78 v 36.76 quality-adjusted life-years). Both arthroscopic repair and Latarjet were cost-effective compared with nonoperative treatment (incremental cost-effectiveness ratios of 3,082 and 1,141, respectively). Results from sensitivity analyses indicate that under scenarios of high rates of stability postoperatively, along with improved clinical outcome scores, revision arthroscopic repair becomes increasingly cost-effective. Latarjet procedure for failed instability repair is a cost-effective treatment option, with lower costs and improved clinical outcomes compared with revision arthroscopic instability repair. However, surgeons must still incorporate clinical judgment into treatment algorithm formation. Level IV, expected value decision analysis. Copyright © 2016. Published by Elsevier Inc.

  7. Light Water Reactor Sustainability Program: Computer-based procedure for field activities: results from three evaluations at nuclear power plants

    International Nuclear Information System (INIS)

    2014-01-01

    Nearly all activities that involve human interaction with the systems of a nuclear power plant are guided by procedures. The paper-based procedures (PBPs) currently used by industry have a demonstrated history of ensuring safety; however, improving procedure use could yield tremendous savings in increased efficiency and safety. One potential way to improve procedure-based activities is through the use of computer-based procedures (CBPs). Computer-based procedures provide the opportunity to incorporate context driven job aids, such as drawings, photos, just-in-time training, etc into CBP system. One obvious advantage of this capability is reducing the time spent tracking down the applicable documentation. Additionally, human performance tools can be integrated in the CBP system in such way that helps the worker focus on the task rather than the tools. Some tools can be completely incorporated into the CBP system, such as pre-job briefs, placekeeping, correct component verification, and peer checks. Other tools can be partly integrated in a fashion that reduces the time and labor required, such as concurrent and independent verification. Another benefit of CBPs compared to PBPs is dynamic procedure presentation. PBPs are static documents which limits the degree to which the information presented can be tailored to the task and conditions when the procedure is executed. The CBP system could be configured to display only the relevant steps based on operating mode, plant status, and the task at hand. A dynamic presentation of the procedure (also known as context-sensitive procedures) will guide the user down the path of relevant steps based on the current conditions. This feature will reduce the user's workload and inherently reduce the risk of incorrectly marking a step as not applicable and the risk of incorrectly performing a step that should be marked as not applicable. As part of the Department of Energy's (DOE) Light Water Reactors Sustainability Program

  8. Mind the gap: results of a multispecialty survey on coordination of care for peri-procedural anticoagulation.

    Science.gov (United States)

    Kurlander, Jacob E; Barnes, Geoffrey D; Anderson, Michelle A; Haymart, Brian; Kline-Rogers, Eva; Kaatz, Scott; Saini, Sameer D; Krein, Sarah L; Richardson, Caroline R; Froehlich, James B

    2018-04-01

    To understand how physicians from various specialties perceive coordination of care when managing peri-procedural anticoagulation. Cross-sectional survey of cardiologists, gastroenterologists, and primary care physicians (PCPs) in an integrated health system (N = 251). The survey began with a vignette of a patient with atrial fibrillation co-managed by his PCP, cardiologist, and an anticoagulation clinic who must hold warfarin for a colonoscopy. Respondents' experiences and opinions around responsibilities and institutional support for managing peri-procedural anticoagulation were elicited using multiple choice questions. We examined differences in responses across specialties using Chi square analysis. The response rate was 51% (n = 127). 52% were PCPs, 28% cardiologists, and 21% gastroenterologists. Nearly half (47.2%) of respondents believed that the cardiologist should be primarily responsible for managing peri-procedural anticoagulation, while fewer identified the PCP (25.2%), anticoagulation clinic (21.3%), or gastroenterologist (6.3%; p = 0.09). Respondents across specialties had significantly different approaches to deciding how to manage the clinical case presented (p procedural anticoagulation, and there was broad support (88.1%) for anticoagulation clinics' managing all aspects of peri-procedural anticoagulation. Providers across specialties agree that their institution could do more to help manage peri-procedural anticoagulation, and overwhelmingly support anticoagulation clinics' taking responsibility.

  9. A model treatment refusal procedure for defendants found incompetent to stand trial in the ninth circuit.

    Science.gov (United States)

    Epson, Martin; Rodol, Liban; Bloom, Joseph D

    2012-01-01

    Pretrial detainees have a constitutionally protected right to refuse medical treatment in most circumstances; however, individuals found incompetent to stand trial (IST) due to a mental disorder can be treated involuntarily by clinicians who adhere to careful medical and legal procedures. The process of involuntary treatment of IST pretrial detainees begins with categorization into particular legal and medical groups. These different categories affect the individual's access to treatment. In this article, we review the relevant case law for the jurisdiction of the Ninth Circuit and place the medical-legal debate regarding these procedures in the context of recent cases. To address the medical-legal disjunction, we propose and discuss a model for managing treatment refusal in pretrial detainees found IST.

  10. Early and Late Results of the Nuss Procedure in Surgical Treatment of Pectus Excavatum in Different Age Groups.

    Science.gov (United States)

    Pawlak, Krystian; Gąsiorowski, Łukasz; Gabryel, Piotr; Gałęcki, Bartłomiej; Zieliński, Paweł; Dyszkiewicz, Wojciech

    2016-11-01

    The aim of this study was a comparison of early and late results in surgical treatment of funnel chest using the Nuss method in patients in various age groups to find the optimal age to perform the corrective procedure. Six hundred eighty patients operated on from June 2002 to October 2012 were included in the retrospective analysis. Patients were divided into 3 different age groups: group A = 156 patients from 7 to 14 years, group B = 328 patients aged 15 to 20 years, and group C = 196 patients older than 20 years of age. The mean follow-up was 33 months. Early non-life-threatening complications developed in 238 (35.0%) patients and frequency increased with age (group A, 24.3%; group B, 37.8%; group C, 38.8%; p = 0.0063). Good and very good corrective effects were achieved in 97.7 % of the entire patient population. Recurrence of the deformity was observed more often in younger patients (group A, 3.2 %) than in the other patients (group B, 1.2%; group C, 1.5%), although the difference between the studied groups was not significant (p = 0.3251). Good cosmetic results obtained with the use of the Nuss operation were not related to the age of the patients. The high incidence of minor complications in older patients seems to be an acceptable cost of a good cosmetic outcome and stable correction. Surgical morbidity is lowest in younger patients; however, the frequency of the recurrence of deformation is higher than in other groups. Copyright © 2016 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

  11. Parratt-based and model-independent X-ray reflectivity fitting procedure for nanoscale thin film characterization.

    Science.gov (United States)

    Yu, Chung-Jong; Kim, Euikwoun; Kim, Jae-Yong

    2011-05-01

    A general-purpose fitting procedure is presented for X-ray reflectivity data. The Parratt formula was used to fit the low-angle region of the reflectivity data and the resulting electron density profile (continuous base EDP or cbEDP) was then divided into a series of electron density slabs of width 1 angstroms (discrete base EDP or dbEDP), which is then easily incorporated into the Distorted Wave Born Approximation (DWBA). An additional series of density slabs of resolution-limited width are overlapped to the dbEDP, and the density value of the each additional slab is allowed to vary to further fit the data model-independently using DWBA. Because this procedure combines the Parratt formula and the model-independent DWBA fitting, each fitting method can always be employed depending on the type of thin film. Moreover, it provides a way to overcome the difficulties when both fitting methods do not work well for certain types of thin films. Simulations show that this procedure is suitable for nanoscale thin film characterization.

  12. Comparison of self-efficacy and its improvement after artificial simulator or live animal model emergency procedure training.

    Science.gov (United States)

    Hall, Andrew B; Riojas, Ramon; Sharon, Danny

    2014-03-01

    The objective of this study is to compare post-training self-efficacy between artificial simulators and live animal training for the performance of emergency medical procedures. Volunteer airmen of the 81st Medical Group, without prior medical procedure training, were randomly assigned to two experimental arms consisting of identical lectures and training of diagnostic peritoneal lavage, thoracostomy (chest tube), and cricothyroidotomy on either the TraumaMan (Simulab Corp., Seattle, Washington) artificial simulator or a live pig (Sus scrofa domestica) model. Volunteers were given a postlecture and postskills training assessment of self-efficacy. Twenty-seven volunteers that initially performed artificial simulator training subsequently underwent live animal training and provided assessments comparing both modalities. The results were first, postskills training self-efficacy scores were significantly higher than postlecture scores for either training mode and for all procedures (p self-efficacy scores were not statistically different between live animal and artificial simulator training for diagnostic peritoneal lavage (p = 0.555), chest tube (p = 0.486), and cricothyroidotomy (p = 0.329). Finally, volunteers undergoing both training modalities indicated preference for live animal training (p self-efficacy after initial training, but there is a preference in using a live animal model to achieve those skills. Reprint & Copyright © 2014 Association of Military Surgeons of the U.S.

  13. Logistic regression modelling: procedures and pitfalls in developing and interpreting prediction models

    Directory of Open Access Journals (Sweden)

    Nataša Šarlija

    2017-01-01

    Full Text Available This study sheds light on the most common issues related to applying logistic regression in prediction models for company growth. The purpose of the paper is 1 to provide a detailed demonstration of the steps in developing a growth prediction model based on logistic regression analysis, 2 to discuss common pitfalls and methodological errors in developing a model, and 3 to provide solutions and possible ways of overcoming these issues. Special attention is devoted to the question of satisfying logistic regression assumptions, selecting and defining dependent and independent variables, using classification tables and ROC curves, for reporting model strength, interpreting odds ratios as effect measures and evaluating performance of the prediction model. Development of a logistic regression model in this paper focuses on a prediction model of company growth. The analysis is based on predominantly financial data from a sample of 1471 small and medium-sized Croatian companies active between 2009 and 2014. The financial data is presented in the form of financial ratios divided into nine main groups depicting following areas of business: liquidity, leverage, activity, profitability, research and development, investing and export. The growth prediction model indicates aspects of a business critical for achieving high growth. In that respect, the contribution of this paper is twofold. First, methodological, in terms of pointing out pitfalls and potential solutions in logistic regression modelling, and secondly, theoretical, in terms of identifying factors responsible for high growth of small and medium-sized companies.

  14. The use of flow models for design of plant operating procedures

    International Nuclear Information System (INIS)

    Lind, M.

    1982-03-01

    The report describe a systematic approach to the design of operating procedures or sequence automatics for process plant control. It is shown how flow models representing the topology of mass and energy flows on different levels of function provide plant information which is important for the considered design problem. The modelling methodology leads to the definition of three categories of control tasks. Two tasks relate to the regulation and control of changes of levels and flows of mass and energy in a system within a defined mode of operation. The third type relate to the control actions necessary for switching operations involved in changes of operating mode. These control tasks are identified for a given plant as part of the flow modelling activity. It is discussed how the flow model deal with the problem of assigning control task precedence in time eg. during start-up or shut-down operations. The method may be a basis for providing automated procedure support to the operator in unforeseen situations or may be a tool for control design. (auth.)

  15. Convergence models for cylindrical caverns and the resulting ground subsidence

    Energy Technology Data Exchange (ETDEWEB)

    Haupt, W.; Sroka, A.; Schober, F.

    1983-02-01

    The authors studied the effects of different convergence characteristics on surface soil response for the case of narrow, cylindrical caverns. Maximum ground subsidence - a parameter of major importance in this type of cavern - was calculated for different convergence models. The models were established without considering the laws of rock mechanics and rheology. As a result, two limiting convergence models were obtained that describe an interval of expectation into which all other models fit. This means that ground movements over cylindrical caverns can be calculated ''on the safe side'', correlating the trough resulting on the surface with the convergence characterisitcs of the cavern. Among other applications, the method thus permits monitoring of caverns.

  16. Light Water Reactor Sustainability Program: Computer-Based Procedures for Field Activities: Results from Three Evaluations at Nuclear Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    Oxstrand, Johanna [Idaho National Lab. (INL), Idaho Falls, ID (United States); Le Blanc, Katya [Idaho National Lab. (INL), Idaho Falls, ID (United States); Bly, Aaron [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2014-09-01

    The Computer-Based Procedure (CBP) research effort is a part of the Light-Water Reactor Sustainability (LWRS) Program, which is a research and development (R&D) program sponsored by Department of Energy (DOE) and performed in close collaboration with industry R&D programs that provides the technical foundations for licensing and managing the long-term, safe, and economical operation of current nuclear power plants. One of the primary missions of the LWRS program is to help the U.S. nuclear industry adopt new technologies and engineering solutions that facilitate the continued safe operation of the plants and extension of the current operating licenses. One area that could yield tremendous savings in increased efficiency and safety is in improving procedure use. Nearly all activities in the nuclear power industry are guided by procedures, which today are printed and executed on paper. This paper-based procedure process has proven to ensure safety; however, there are improvements to be gained. Due to its inherent dynamic nature, a CBP provides the opportunity to incorporate context driven job aids, such as drawings, photos, and just-in-time training. Compared to the static state of paper-based procedures (PBPs), the presentation of information in CBPs can be much more flexible and tailored to the task, actual plant condition, and operation mode. The dynamic presentation of the procedure will guide the user down the path of relevant steps, thus minimizing time spent by the field worker to evaluate plant conditions and decisions related to the applicability of each step. This dynamic presentation of the procedure also minimizes the risk of conducting steps out of order and/or incorrectly assessed applicability of steps.

  17. Meteorological Uncertainty of atmospheric Dispersion model results (MUD)

    DEFF Research Database (Denmark)

    Havskov Sørensen, Jens; Amstrup, Bjarne; Feddersen, Henrik

    . However, recent developments in numerical weather prediction (NWP) include probabilistic forecasting techniques, which can be utilised also for atmospheric dispersion models. The ensemble statistical methods developed and applied to NWP models aim at describing the inherent uncertainties......The MUD project addresses assessment of uncertainties of atmospheric dispersion model predictions, as well as optimum presentation to decision makers. Previously, it has not been possible to estimate such uncertainties quantitatively, but merely to calculate the 'most likely' dispersion scenario...... of the meteorological model results. These uncertainties stem from e.g. limits in meteorological obser-vations used to initialise meteorological forecast series. By perturbing the initial state of an NWP model run in agreement with the available observa-tional data, an ensemble of meteorological forecasts is produced...

  18. Meteorological Uncertainty of atmospheric Dispersion model results (MUD)

    DEFF Research Database (Denmark)

    Havskov Sørensen, Jens; Amstrup, Bjarne; Feddersen, Henrik

    ’ dispersion scenario. However, recent developments in numerical weather prediction (NWP) include probabilistic forecasting techniques, which can be utilised also for long-range atmospheric dispersion models. The ensemble statistical methods developed and applied to NWP models aim at describing the inherent......The MUD project addresses assessment of uncertainties of atmospheric dispersion model predictions, as well as possibilities for optimum presentation to decision makers. Previously, it has not been possible to estimate such uncertainties quantitatively, but merely to calculate the ‘most likely...... uncertainties of the meteorological model results. These uncertainties stem from e.g. limits in meteorological observations used to initialise meteorological forecast series. By perturbing e.g. the initial state of an NWP model run in agreement with the available observational data, an ensemble...

  19. Building Energy Simulation Test for Existing Homes (BESTEST-EX): Instructions for Implementing the Test Procedure, Calibration Test Reference Results, and Example Acceptance-Range Criteria

    Energy Technology Data Exchange (ETDEWEB)

    Judkoff, R.; Polly, B.; Bianchi, M.; Neymark, J.; Kennedy, M.

    2011-08-01

    This publication summarizes building energy simulation test for existing homes (BESTEST-EX): instructions for implementing the test procedure, calibration tests reference results, and example acceptance-range criteria.

  20. The 2013 European Seismic Hazard Model: key components and results

    OpenAIRE

    Jochen Woessner; Danciu Laurentiu; Domenico Giardini; Helen Crowley; Fabrice Cotton; G. Grünthal; Gianluca Valensise; Ronald Arvidsson; Roberto Basili; Mine Betül Demircioglu; Stefan Hiemer; Carlo Meletti; Roger W. Musson; Andrea N. Rovida; Karin Sesetyan

    2015-01-01

    The 2013 European Seismic Hazard Model (ESHM13) results from a community-based probabilistic seismic hazard assessment supported by the EU-FP7 project “Seismic Hazard Harmonization in Europe” (SHARE, 2009–2013). The ESHM13 is a consistent seismic hazard model for Europe and Turkey which overcomes the limitation of national borders and includes a through quantification of the uncertainties. It is the first completed regional effort contributing to the “Global Earthquake Model” initiative. It m...

  1. Hydroclimatology of the Nile: results from a regional climate model

    Directory of Open Access Journals (Sweden)

    Y. A. Mohamed

    2005-01-01

    Full Text Available This paper presents the result of the regional coupled climatic and hydrologic model of the Nile Basin. For the first time the interaction between the climatic processes and the hydrological processes on the land surface have been fully coupled. The hydrological model is driven by the rainfall and the energy available for evaporation generated in the climate model, and the runoff generated in the catchment is again routed over the wetlands of the Nile to supply moisture for atmospheric feedback. The results obtained are quite satisfactory given the extremely low runoff coefficients in the catchment. The paper presents the validation results over the sub-basins: Blue Nile, White Nile, Atbara river, the Sudd swamps, and the Main Nile for the period 1995 to 2000. Observational datasets were used to evaluate the model results including radiation, precipitation, runoff and evaporation data. The evaporation data were derived from satellite images over a major part of the Upper Nile. Limitations in both the observational data and the model are discussed. It is concluded that the model provides a sound representation of the regional water cycle over the Nile. The sources of atmospheric moisture to the basin, and location of convergence/divergence fields could be accurately illustrated. The model is used to describe the regional water cycle in the Nile basin in terms of atmospheric fluxes, land surface fluxes and land surface-climate feedbacks. The monthly moisture recycling ratio (i.e. locally generated/total precipitation over the Nile varies between 8 and 14%, with an annual mean of 11%, which implies that 89% of the Nile water resources originates from outside the basin physical boundaries. The monthly precipitation efficiency varies between 12 and 53%, and the annual mean is 28%. The mean annual result of the Nile regional water cycle is compared to that of the Amazon and the Mississippi basins.

  2. Results of a model for premixed combustion oscillations

    Energy Technology Data Exchange (ETDEWEB)

    Janus, M.C.; Richards, G.A.

    1996-09-01

    Combustion oscillations are receiving renewed research interest due to increasing use of lean premix (LPM) combustion to gas turbines. A simple, nonlinear model for premixed combustion is described in this paper. The model was developed to help explain specific experimental observations and to provide guidance for development of active control schemes based on nonlinear concepts. The model can be used to quickly examine instability trends associated with changes in equivalence ratio, mass flow rate, geometry, ambient conditions, etc. The model represents the relevant processes occurring in a fuel nozzle and combustor which are analogous to current LPM turbine combustors. Conservation equations for the fuel nozzle and combustor are developed from simple control volume analysis, providing a set of ordinary differential equations that can be solved on a personal computer. Combustion is modeled as a stirred reactor, with a bimolecular reaction rate between fuel and air. A variety of numerical results and comparisons to experimental data are presented to demonstrate the utility of the model. Model results are used to understand the fundamental mechanisms which drive combustion oscillations, effects of inlet air temperature and nozzle geometry on instability, and effectiveness of open loop control schemes.

  3. [Sequential intervention with primary excision and Limberg plastic surgery procedure for treatment of sacrococcygeal pilonidal sinus : Results of a pilot study].

    Science.gov (United States)

    Ardelt, M; Dittmar, Y; Scheuerlein, H; Fahrner, R; Rauchfuß, F; Settmacher, U

    2015-08-01

    The current German S3 guidelines recommend radical excision for pilonidal sinus disease. Furthermore, the Karydakis operation and the plastic surgery procedure according to Limberg are also recommended. Contrary to the S2 guidelines of 2008, these two plastic surgery procedures for coverage are recommended for the treatment of the first-time manifestation of this disease. Most studies on the classical Limberg plastic surgical procedure are comparative in nature and describe a simultaneous intervention from which patients with an abscess are excluded. The aim of this present study was to analyze the results of a sequential procedure including primary excision followed by a Limberg plastic surgery procedure for the treatment of acute abscesses and chronic pilonidal sinus disease. From July 2010 to June 2013 a total of 50 patients with pilonidal sinus disease were treated at the University Hospital Jena with an initial radical excision. In accordance with the Association of the Scientific Medical Societies in Germany (AWMF) guidelines which were valid during that time, patients were offered plastic surgery coverage for recurrence prophylaxis and in cases of recurrence a Limberg plastic surgery procedure was recommended. Of the 50 patients 22 opted for a Limberg plastic surgery procedure during the interval. The mean follow-up after the Limberg plastic surgery procedure was 20.1 months (range 2-36 months). During the follow-up period, there were no recurrences (0 %) but four major complications (18.2 %) and one minor complication (4.5 %) were observed. This concept can be applied in cases of acute abscess formation and in chronic pilonidal sinus disease. The patient's decision with respect to a Limberg plastic surgery procedure for recurrence prophylaxis does not have to be made immediately. In addition, the Limberg plastic surgery procedure is performed in an infection-free stage. The second inpatient stay, second surgical procedure and prolonged time off work are a

  4. Soft tissue cell adhesion to titanium abutments after different cleaning procedures: Preliminary results of a randomized clinical trial

    Science.gov (United States)

    Canullo, Luigi; Peñarrocha-Oltra, David; Marchionni, Silvia; Bagán, Leticia; Micarelli, Costanza

    2014-01-01

    Objectives: A randomized controlled trial was performed to assess soft tissue cell adhesion to implant titanium abutments subjected to different cleaning procedures and test if plasma cleaning can enhance cell adhesion at an early healing time. Study Design: Eighteen patients with osseointegrated and submerged implants were included. Before re-opening, 18 abutments were divided in 3 groups corresponding to different clinical conditions with different cleaning processes: no treatment (G1), laboratory customization and cleaning by steam (G2), cleaning by plasma of Argon (G3). Abutments were removed after 1 week and scanning electron microscopy was used to analyze cell adhesion to the abutment surface quantitatively (percentage of area occupied by cells) and qualitatively (aspect of adhered cells and presence of contaminants). Results: Mean percentages of area occupied by cells were 17.6 ± 22.7%, 16.5 ± 12.9% and 46.3 ± 27.9% for G1, G2 and G3 respectively. Differences were statistically significant between G1 and G3 (p=0.030), close to significance between G2 and G3 (p=0.056), and non-significant between G1 and G2 (p=0.530). The proportion of samples presenting adhered cells was homogeneous among the 3 groups (p-valor = 1.000). In all cases cells presented a flattened aspect; in 2 cases cells were less efficiently adhered and in 1 case cells presented filipodia. Three cases showed contamination with cocobacteria. Conclusions: Within the limits of the present study, plasma of Argon may enhance cell adhesion to titanium abutments, even at the early stage of soft tissue healing. Further studies with greater samples are necessary to confirm these findings. Key words:Connective tissue, dental abutments, randomized controlled trial, clinical research, glow discharged abutment, plasma cleaning. PMID:24121917

  5. Nitrous oxide emissions from cropland: a procedure for calibrating the DayCent biogeochemical model using inverse modelling

    Science.gov (United States)

    Rafique, Rashad; Fienen, Michael N.; Parkin, Timothy B.; Anex, Robert P.

    2013-01-01

    DayCent is a biogeochemical model of intermediate complexity widely used to simulate greenhouse gases (GHG), soil organic carbon and nutrients in crop, grassland, forest and savannah ecosystems. Although this model has been applied to a wide range of ecosystems, it is still typically parameterized through a traditional “trial and error” approach and has not been calibrated using statistical inverse modelling (i.e. algorithmic parameter estimation). The aim of this study is to establish and demonstrate a procedure for calibration of DayCent to improve estimation of GHG emissions. We coupled DayCent with the parameter estimation (PEST) software for inverse modelling. The PEST software can be used for calibration through regularized inversion as well as model sensitivity and uncertainty analysis. The DayCent model was analysed and calibrated using N2O flux data collected over 2 years at the Iowa State University Agronomy and Agricultural Engineering Research Farms, Boone, IA. Crop year 2003 data were used for model calibration and 2004 data were used for validation. The optimization of DayCent model parameters using PEST significantly reduced model residuals relative to the default DayCent parameter values. Parameter estimation improved the model performance by reducing the sum of weighted squared residual difference between measured and modelled outputs by up to 67 %. For the calibration period, simulation with the default model parameter values underestimated mean daily N2O flux by 98 %. After parameter estimation, the model underestimated the mean daily fluxes by 35 %. During the validation period, the calibrated model reduced sum of weighted squared residuals by 20 % relative to the default simulation. Sensitivity analysis performed provides important insights into the model structure providing guidance for model improvement.

  6. A stochastic estimation procedure for intermittently-observed semi-Markov multistate models with back transitions.

    Science.gov (United States)

    Aralis, Hilary; Brookmeyer, Ron

    2017-01-01

    Multistate models provide an important method for analyzing a wide range of life history processes including disease progression and patient recovery following medical intervention. Panel data consisting of the states occupied by an individual at a series of discrete time points are often used to estimate transition intensities of the underlying continuous-time process. When transition intensities depend on the time elapsed in the current state and back transitions between states are possible, this intermittent observation process presents difficulties in estimation due to intractability of the likelihood function. In this manuscript, we present an iterative stochastic expectation-maximization algorithm that relies on a simulation-based approximation to the likelihood function and implement this algorithm using rejection sampling. In a simulation study, we demonstrate the feasibility and performance of the proposed procedure. We then demonstrate application of the algorithm to a study of dementia, the Nun Study, consisting of intermittently-observed elderly subjects in one of four possible states corresponding to intact cognition, impaired cognition, dementia, and death. We show that the proposed stochastic expectation-maximization algorithm substantially reduces bias in model parameter estimates compared to an alternative approach used in the literature, minimal path estimation. We conclude that in estimating intermittently observed semi-Markov models, the proposed approach is a computationally feasible and accurate estimation procedure that leads to substantial improvements in back transition estimates.

  7. Modeling urban building energy use: A review of modeling approaches and procedures

    Energy Technology Data Exchange (ETDEWEB)

    Li, Wenliang; Zhou, Yuyu; Cetin, Kristen; Eom, Jiyong; Wang, Yu; Chen, Gang; Zhang, Xuesong

    2017-12-01

    With rapid urbanization and economic development, the world has been experiencing an unprecedented increase in energy consumption and greenhouse gas (GHG) emissions. While reducing energy consumption and GHG emissions is a common interest shared by major developed and developing countries, actions to enable these global reductions are generally implemented at the city scale. This is because baseline information from individual cities plays an important role in identifying economical options for improving building energy efficiency and reducing GHG emissions. Numerous approaches have been proposed for modeling urban building energy use in the past decades. This paper aims to provide an up-to-date review of the broad categories of energy models for urban buildings and describes the basic workflow of physics-based, bottom-up models and their applications in simulating urban-scale building energy use. Because there are significant differences across models with varied potential for application, strengths and weaknesses of the reviewed models are also presented. This is followed by a discussion of challenging issues associated with model preparation and calibration.

  8. Modeling of the LA-ICPMS surface rastering procedure to optimize elemental imaging

    International Nuclear Information System (INIS)

    Elteren, J.T. van; Triglav, J.; Selih, V.S.; Zivin, M.

    2009-01-01

    Full text: The quality of elemental image maps generated by LA-ICPMS is a function of the instrumental settings (laser fluence, pulse rate, beam diameter, scanning speed, gas flow rate and acquisition time). Optimizing these settings is a matter of trial and error since quality criteria for elemental imaging (sensitivity, resolution, analysis time) are intricately linked. A theoretical model (and software) will be discussed with which it is possible to simply compute the image distortion introduced by the LA-ICPMS as a function of the instrumental settings and optimize the surface rastering procedure prior to the actual analysis to meet the required quality criteria. (author)

  9. Relationship Marketing results: proposition of a cognitive mapping model

    Directory of Open Access Journals (Sweden)

    Iná Futino Barreto

    2015-12-01

    Full Text Available Objective - This research sought to develop a cognitive model that expresses how marketing professionals understand the relationship between the constructs that define relationship marketing (RM. It also tried to understand, using the obtained model, how objectives in this field are achieved. Design/methodology/approach – Through cognitive mapping, we traced 35 individual mental maps, highlighting how each respondent understands the interactions between RM elements. Based on the views of these individuals, we established an aggregate mental map. Theoretical foundation – The topic is based on a literature review that explores the RM concept and its main elements. Based on this review, we listed eleven main constructs. Findings – We established an aggregate mental map that represents the RM structural model. Model analysis identified that CLV is understood as the final result of RM. We also observed that the impact of most of the RM elements on CLV is brokered by loyalty. Personalization and quality, on the other hand, proved to be process input elements, and are the ones that most strongly impact others. Finally, we highlight that elements that punish customers are much less effective than elements that benefit them. Contributions - The model was able to insert core elements of RM, but absent from most formal models: CLV and customization. The analysis allowed us to understand the interactions between the RM elements and how the end result of RM (CLV is formed. This understanding improves knowledge on the subject and helps guide, assess and correct actions.

  10. Clinical results of a brindley procedure: sacral anterior root stimulation in combination with a rhizotomy of the dorsal roots

    NARCIS (Netherlands)

    Martens, F.M.J.; Heesakkers, J.P.F.A.

    2011-01-01

    The Brindley procedure consists of a stimulator for sacral anterior-root stimulation and a rhizotomy of the dorsal sacral roots to abolish neurogenic detrusor overactivity. Stimulation of the sacral anterior roots enables micturition, defecation, and erections. This overview discusses the technique,

  11. Common handling procedures conducted in preclinical safety studies result in minimal hepatic gene expression changes in Sprague-Dawley rats.

    Directory of Open Access Journals (Sweden)

    Yudong D He

    Full Text Available Gene expression profiling is a tool to gain mechanistic understanding of adverse effects in response to compound exposure. However, little is known about how the common handling procedures of experimental animals during a preclinical study alter baseline gene expression. We report gene expression changes in the livers of female Sprague-Dawley rats following common handling procedures. Baseline gene expression changes identified in this study provide insight on how these changes may affect interpretation of gene expression profiles following compound exposure. Rats were divided into three groups. One group was not subjected to handling procedures and served as controls for both handled groups. Animals in the other two groups were weighed, subjected to restraint in Broome restrainers, and administered water via oral gavage daily for 1 or 4 days with tail vein blood collections at 1, 2, 4, and 8 hours postdose on days 1 and 4. Significantly altered genes were identified in livers of animals following 1 or 4 days of handling when compared to the unhandled animals. Gene changes in animals handled for 4 days were similar to those handled for 1 day, suggesting a lack of habituation. The altered genes were primarily immune function related genes. These findings, along with a correlating increase in corticosterone levels suggest that common handling procedures may cause a minor immune system perturbance.

  12. Establishing reliable cognitive change in children with epilepsy: The procedures and results for a sample with epilepsy

    NARCIS (Netherlands)

    van Iterson, L.; Augustijn, P.B.; de Jong, P.F.; van der Leij, A.

    2013-01-01

    The goal of this study was to investigate reliable cognitive change in epilepsy by developing computational procedures to determine reliable change index scores (RCIs) for the Dutch Wechsler Intelligence Scales for Children. First, RCIs were calculated based on stability coefficients from a

  13. Establishing Reliable Cognitive Change in Children with Epilepsy: The Procedures and Results for a Sample with Epilepsy

    Science.gov (United States)

    van Iterson, Loretta; Augustijn, Paul B.; de Jong, Peter F.; van der Leij, Aryan

    2013-01-01

    The goal of this study was to investigate reliable cognitive change in epilepsy by developing computational procedures to determine reliable change index scores (RCIs) for the Dutch Wechsler Intelligence Scales for Children. First, RCIs were calculated based on stability coefficients from a reference sample. Then, these RCIs were applied to a…

  14. Fitting direct covariance structures by the MSTRUCT modeling language of the CALIS procedure.

    Science.gov (United States)

    Yung, Yiu-Fai; Browne, Michael W; Zhang, Wei

    2015-02-01

    This paper demonstrates the usefulness and flexibility of the general structural equation modelling (SEM) approach to fitting direct covariance patterns or structures (as opposed to fitting implied covariance structures from functional relationships among variables). In particular, the MSTRUCT modelling language (or syntax) of the CALIS procedure (SAS/STAT version 9.22 or later: SAS Institute, 2010) is used to illustrate the SEM approach. The MSTRUCT modelling language supports a direct covariance pattern specification of each covariance element. It also supports the input of additional independent and dependent parameters. Model tests, fit statistics, estimates, and their standard errors are then produced under the general SEM framework. By using numerical and computational examples, the following tests of basic covariance patterns are illustrated: sphericity, compound symmetry, and multiple-group covariance patterns. Specification and testing of two complex correlation structures, the circumplex pattern and the composite direct product models with or without composite errors and scales, are also illustrated by the MSTRUCT syntax. It is concluded that the SEM approach offers a general and flexible modelling of direct covariance and correlation patterns. In conjunction with the use of SAS macros, the MSTRUCT syntax provides an easy-to-use interface for specifying and fitting complex covariance and correlation structures, even when the number of variables or parameters becomes large. © 2014 The British Psychological Society.

  15. The Use of a Probit Model for the Validation of Selection Procedures.

    Science.gov (United States)

    Dagenais, Denyse L.

    1984-01-01

    After a review of the disadvantages of linear models for estimating the probability of academic success from previous school records and admission test results, the use of a probit model is proposed. The model is illustrated with admissions data from the Ecole des Hautes Etudes Commerciales in Montreal. (Author/BW)

  16. Modeling Results For the ITER Cryogenic Fore Pump. Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Pfotenhauer, John M. [University of Wisconsin, Madison, WI (United States); Zhang, Dongsheng [University of Wisconsin, Madison, WI (United States)

    2014-03-31

    A numerical model characterizing the operation of a cryogenic fore-pump (CFP) for ITER has been developed at the University of Wisconsin – Madison during the period from March 15, 2011 through June 30, 2014. The purpose of the ITER-CFP is to separate hydrogen isotopes from helium gas, both making up the exhaust components from the ITER reactor. The model explicitly determines the amount of hydrogen that is captured by the supercritical-helium-cooled pump as a function of the inlet temperature of the supercritical helium, its flow rate, and the inlet conditions of the hydrogen gas flow. Furthermore the model computes the location and amount of hydrogen captured in the pump as a function of time. Throughout the model’s development, and as a calibration check for its results, it has been extensively compared with the measurements of a CFP prototype tested at Oak Ridge National Lab. The results of the model demonstrate that the quantity of captured hydrogen is very sensitive to the inlet temperature of the helium coolant on the outside of the cryopump. Furthermore, the model can be utilized to refine those tests, and suggests methods that could be incorporated in the testing to enhance the usefulness of the measured data.

  17. The Open Abdomen Route by EuraHS: introduction of the data set and initial results of procedures and procedure-related complications.

    Science.gov (United States)

    Willms, A; Muysoms, F; Güsgen, C; Schwab, R; Lock, J; Schaaf, S; Germer, C; Richardsen, I; Dietz, U

    2017-04-01

    Open abdomen management has become a well-established strategy in the treatment of serious intra-abdominal pathologies. Key objectives are fistula prevention and high fascial closure rates. The current level of evidence on laparostoma is insufficient. This is due to the rareness of laparostomas, the heterogeneity of study cohorts, and broad diversity of techniques. Collecting data in a standardised, multicentre registry is necessary to draw up evidence-based guidelines. In order to improve the level of evidence on laparostomy, CAMIN (surgical working group for military and emergency surgery) of DGAV (German Society for General and Visceral Surgery), initiated the implementation of a laparostomy registry. This registry was established as the Open Abdomen Route by EuraHS (European Registry of Abdominal Wall Hernias). Key objectives include collection of data, quality assurance, standardisation of therapeutic concepts and the development of guidelines. Since 1 May 2015, the registry is available as an online database called Open Abdomen Route of EuraHS (European Registry of Abdominal Wall Hernias). It includes 11 categories for data collection, including three scheduled follow-up examinations. As part of this pilot study, all entries of the first 120 days were analysed, resulting in a review of 82 patients. At 44%, secondary peritonitis was the predominant indication. The mortality rate was 22%. A comparison of methods with and without fascial traction reveals fascial closure rates of 67% and 25%, respectively (intention-to-treat analysis, p open abdomen treatment.

  18. Fuel assembly bow: analytical modeling and resulting design improvements

    International Nuclear Information System (INIS)

    Stabel, J.; Huebsch, H.P.

    1995-01-01

    The bowing of fuel assemblies may result in a contact between neighbouring fuel assemblies and in connection with a vibration to a resulting wear or even perforation at the corners of the spacer grids of neighbouring assemblies. Such events allowed reinsertion of a few fuel assemblies in Germany only after spacer repair. In order to identify the most sensitive parameters causing the observed bowing of fuel assemblies a new computer model was develop which takes into a account the highly nonlinear behaviour of the interaction between fuel rods and spacers. As a result of the studies performed with this model, design improvements such as a more rigid connection between guide thimbles and spacer grids, could be defined. First experiences with this improved design show significantly better fuel behaviour. (author). 5 figs., 1 tabs

  19. Innovative procedure for computer-assisted genioplasty: three-dimensional cephalometry, rapid-prototyping model and surgical splint.

    Science.gov (United States)

    Olszewski, R; Tranduy, K; Reychler, H

    2010-07-01

    The authors present a new procedure of computer-assisted genioplasty. They determined the anterior, posterior and inferior limits of the chin in relation to the skull and face with the newly developed and validated three-dimensional cephalometric planar analysis (ACRO 3D). Virtual planning of the osteotomy lines was carried out with Mimics (Materialize) software. The authors built a three-dimensional rapid-prototyping multi-position model of the chin area from a medical low-dose CT scan. The transfer of virtual information to the operating room consisted of two elements. First, the titanium plates on the 3D RP model were pre-bent. Second, a surgical guide for the transfer of the osteotomy lines and the positions of the screws to the operating room was manufactured. The authors present the first case of the use of this model on a patient. The postoperative results are promising, and the technique is fast and easy-to-use. More patients are needed for a definitive clinical validation of this procedure. Copyright 2010 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

  20. A Tractable Model of the LTE Access Reservation Procedure for Machine-Type Communications

    DEFF Research Database (Denmark)

    Nielsen, Jimmy Jessen; Min Kim, Dong; Madueño, Germán Corrales

    2015-01-01

    A canonical scenario in Machine-Type Communications (MTC) is the one featuring a large number of devices, each of them with sporadic traffic. Hence, the number of served devices in a single LTE cell is not determined by the available aggregate rate, but rather by the limitations of the LTE access...... reservation protocol. Specifically, the limited number of contention preambles and the limited amount of uplink grants per random access response are crucial to consider when dimensioning LTE networks for MTC. We propose a low-complexity model that encompasses these two limitations and allows us to evaluate...... on the preamble collisions. A comparison with the simulated LTE access reservation procedure that follows the 3GPP specifications, confirms that our model provides an accurate estimation of the system outage event and the number of supported MTC devices....

  1. Methodology and Results of Mathematical Modelling of Complex Technological Processes

    Science.gov (United States)

    Mokrova, Nataliya V.

    2018-03-01

    The methodology of system analysis allows us to draw a mathematical model of the complex technological process. The mathematical description of the plasma-chemical process was proposed. The importance the quenching rate and initial temperature decrease time was confirmed for producing the maximum amount of the target product. The results of numerical integration of the system of differential equations can be used to describe reagent concentrations, plasma jet rate and temperature in order to achieve optimal mode of hardening. Such models are applicable both for solving control problems and predicting future states of sophisticated technological systems.

  2. Modeling vertical loads in pools resulting from fluid injection. [BWR

    Energy Technology Data Exchange (ETDEWEB)

    Lai, W.; McCauley, E.W.

    1978-06-15

    Table-top model experiments were performed to investigate pressure suppression pool dynamics effects due to a postulated loss-of-coolant accident (LOCA) for the Peachbottom Mark I boiling water reactor containment system. The results guided subsequent conduct of experiments in the /sup 1///sub 5/-scale facility and provided new insight into the vertical load function (VLF). Model experiments show an oscillatory VLF with the download typically double-spiked followed by a more gradual sinusoidal upload. The load function contains a high frequency oscillation superimposed on a low frequency one; evidence from measurements indicates that the oscillations are initiated by fluid dynamics phenomena.

  3. Modeling vertical loads in pools resulting from fluid injection

    International Nuclear Information System (INIS)

    Lai, W.; McCauley, E.W.

    1978-01-01

    Table-top model experiments were performed to investigate pressure suppression pool dynamics effects due to a postulated loss-of-coolant accident (LOCA) for the Peachbottom Mark I boiling water reactor containment system. The results guided subsequent conduct of experiments in the 1 / 5 -scale facility and provided new insight into the vertical load function (VLF). Model experiments show an oscillatory VLF with the download typically double-spiked followed by a more gradual sinusoidal upload. The load function contains a high frequency oscillation superimposed on a low frequency one; evidence from measurements indicates that the oscillations are initiated by fluid dynamics phenomena

  4. Some results on the dynamics generated by the Bazykin model

    Directory of Open Access Journals (Sweden)

    Georgescu, R M

    2006-07-01

    Full Text Available A predator-prey model formerly proposed by A. Bazykin et al. [Bifurcation diagrams of planar dynamical systems (1985] is analyzed in the case when two of the four parameters are kept fixed. Dynamics and bifurcation results are deduced by using the methods developed by D. K. Arrowsmith and C. M. Place [Ordinary differential equations (1982], S.-N. Chow et al. [Normal forms and bifurcation of planar fields (1994], Y. A. Kuznetsov [Elements of applied bifurcation theory (1998], and A. Georgescu [Dynamic bifurcation diagrams for some models in economics and biology (2004]. The global dynamic bifurcation diagram is constructed and graphically represented. The biological interpretation is presented, too.

  5. Procedural Portfolio Planning in Plastic Surgery, Part 2: Collaboration Between Surgeons and Hospital Administrators to Develop a Funds Flow Model for Procedures Performed at an Academic Medical Center.

    Science.gov (United States)

    Hultman, Charles Scott

    2016-06-01

    Although plastic surgeons make important contributions to the clinical, educational, and research missions of academic medical centers (AMCs), determining the financial value of a plastic surgery service can be difficult, due to complex cost accounting systems. We analyzed the financial impact of plastic surgery on an AMC, by examining the contribution margins and operating income of surgical procedures. We collaborated with hospital administrators to implement 3 types of strategic changes: (1) growth of areas with high contribution margin, (2) curtailment of high-risk procedures with negative contribution margin, (3) improved efficiency of mission-critical services with high resource consumption. Outcome measures included: facility charges, hospital collections, contribution margin, operating margin, and operating room times. We also studied the top 50 Current Procedural Terminology codes (total case number × charge/case), ranking procedures for profitability, as determined by operating margin. During the 2-year study period, we had no turnover in faculty; did not pursue any formal marketing; did not change our surgical fees, billing system, or payer mix; and maintained our commitment to indigent care. After rebalancing our case mix, through procedural portfolio planning, average hospital operating income/procedure increased from $-79 to $+816. Volume and diversity of cases increased, with no change in payer mix. Although charges/case decreased, both contribution margin and operating margin increased, due to improved throughput and decreased operating room times. The 5 most profitable procedures for the hospital were hernia repair, mandibular osteotomy, hand skin graft, free fibula flap, and head and neck flap, whereas the 5 least profitable were latissimus breast reconstruction, craniosynostosis repair, free-flap breast reconstruction, trunk skin graft, and cutaneous free flap. Total operating income for the hospital, from plastic surgery procedures, increased

  6. Results of the eruptive column model inter-comparison study

    Science.gov (United States)

    Costa, Antonio; Suzuki, Yujiro; Cerminara, M.; Devenish, Ben J.; Esposti Ongaro, T.; Herzog, Michael; Van Eaton, Alexa; Denby, L.C.; Bursik, Marcus; de' Michieli Vitturi, Mattia; Engwell, S.; Neri, Augusto; Barsotti, Sara; Folch, Arnau; Macedonio, Giovanni; Girault, F.; Carazzo, G.; Tait, S.; Kaminski, E.; Mastin, Larry G.; Woodhouse, Mark J.; Phillips, Jeremy C.; Hogg, Andrew J.; Degruyter, Wim; Bonadonna, Costanza

    2016-01-01

    This study compares and evaluates one-dimensional (1D) and three-dimensional (3D) numerical models of volcanic eruption columns in a set of different inter-comparison exercises. The exercises were designed as a blind test in which a set of common input parameters was given for two reference eruptions, representing a strong and a weak eruption column under different meteorological conditions. Comparing the results of the different models allows us to evaluate their capabilities and target areas for future improvement. Despite their different formulations, the 1D and 3D models provide reasonably consistent predictions of some of the key global descriptors of the volcanic plumes. Variability in plume height, estimated from the standard deviation of model predictions, is within ~ 20% for the weak plume and ~ 10% for the strong plume. Predictions of neutral buoyancy level are also in reasonably good agreement among the different models, with a standard deviation ranging from 9 to 19% (the latter for the weak plume in a windy atmosphere). Overall, these discrepancies are in the range of observational uncertainty of column height. However, there are important differences amongst models in terms of local properties along the plume axis, particularly for the strong plume. Our analysis suggests that the simplified treatment of entrainment in 1D models is adequate to resolve the general behaviour of the weak plume. However, it is inadequate to capture complex features of the strong plume, such as large vortices, partial column collapse, or gravitational fountaining that strongly enhance entrainment in the lower atmosphere. We conclude that there is a need to more accurately quantify entrainment rates, improve the representation of plume radius, and incorporate the effects of column instability in future versions of 1D volcanic plume models.

  7. Estimating multilevel logistic regression models when the number of clusters is low: a comparison of different statistical software procedures.

    Science.gov (United States)

    Austin, Peter C

    2010-04-22

    Multilevel logistic regression models are increasingly being used to analyze clustered data in medical, public health, epidemiological, and educational research. Procedures for estimating the parameters of such models are available in many statistical software packages. There is currently little evidence on the minimum number of clusters necessary to reliably fit multilevel regression models. We conducted a Monte Carlo study to compare the performance of different statistical software procedures for estimating multilevel logistic regression models when the number of clusters was low. We examined procedures available in BUGS, HLM, R, SAS, and Stata. We found that there were qualitative differences in the performance of different software procedures for estimating multilevel logistic models when the number of clusters was low. Among the likelihood-based procedures, estimation methods based on adaptive Gauss-Hermite approximations to the likelihood (glmer in R and xtlogit in Stata) or adaptive Gaussian quadrature (Proc NLMIXED in SAS) tended to have superior performance for estimating variance components when the number of clusters was small, compared to software procedures based on penalized quasi-likelihood. However, only Bayesian estimation with BUGS allowed for accurate estimation of variance components when there were fewer than 10 clusters. For all statistical software procedures, estimation of variance components tended to be poor when there were only five subjects per cluster, regardless of the number of clusters.

  8. A Procedure for Determining Tire-Road Friction Characteristics Using a Modification of the Magic Formula Based on Experimental Results

    Science.gov (United States)

    Pérez, Javier; Velasco, Juan M.; Guerra, Antonio J.; Hernández, Pedro

    2018-01-01

    Knowledge of tire-road friction characteristics is essential for the proper performance of most relevant vehicle active safety systems. Therefore, its determination is necessary to improve the effectiveness of these systems and to avoid or reduce the consequences of traffic accidents. For this reason, there is a great deal of literature concerning methods and devices for measuring and modeling tire-road friction. Most of these methods have focused on determining the road friction resistance, taking only road composition and making measurements in wet conditions into account. However, friction forces are also dependent on the tire type, since the contact is established between the tire and the road in real driving conditions. Thus, the type and characteristics of the tire have to be considered in the study of the interaction between the vehicle and the road. The aim of this work is to unify the study of the friction coefficient, taking into consideration the two existing bodies involved in the contact, i.e., the tire and road and the main factors that influence the forces in the contact. To this end, a modification of the Pacejka Magic Formula is proposed to include the effects of the main parameters that influence the contact, such as road composition and its state, tire type, vehicle speed, and slip between the tire and the road. To do so, real tests have been conducted on several roads and with different operating conditions. As a result, a more accurate tire-road friction model has been obtained. PMID:29562623

  9. A Procedure for Determining Tire-Road Friction Characteristics Using a Modification of the Magic Formula Based on Experimental Results

    Directory of Open Access Journals (Sweden)

    Juan A. Cabrera

    2018-03-01

    Full Text Available Knowledge of tire-road friction characteristics is essential for the proper performance of most relevant vehicle active safety systems. Therefore, its determination is necessary to improve the effectiveness of these systems and to avoid or reduce the consequences of traffic accidents. For this reason, there is a great deal of literature concerning methods and devices for measuring and modeling tire-road friction. Most of these methods have focused on determining the road friction resistance, taking only road composition and making measurements in wet conditions into account. However, friction forces are also dependent on the tire type, since the contact is established between the tire and the road in real driving conditions. Thus, the type and characteristics of the tire have to be considered in the study of the interaction between the vehicle and the road. The aim of this work is to unify the study of the friction coefficient, taking into consideration the two existing bodies involved in the contact, i.e., the tire and road and the main factors that influence the forces in the contact. To this end, a modification of the Pacejka Magic Formula is proposed to include the effects of the main parameters that influence the contact, such as road composition and its state, tire type, vehicle speed, and slip between the tire and the road. To do so, real tests have been conducted on several roads and with different operating conditions. As a result, a more accurate tire-road friction model has been obtained.

  10. A Procedure for Determining Tire-Road Friction Characteristics Using a Modification of the Magic Formula Based on Experimental Results.

    Science.gov (United States)

    Cabrera, Juan A; Castillo, Juan J; Pérez, Javier; Velasco, Juan M; Guerra, Antonio J; Hernández, Pedro

    2018-03-17

    Knowledge of tire-road friction characteristics is essential for the proper performance of most relevant vehicle active safety systems. Therefore, its determination is necessary to improve the effectiveness of these systems and to avoid or reduce the consequences of traffic accidents. For this reason, there is a great deal of literature concerning methods and devices for measuring and modeling tire-road friction. Most of these methods have focused on determining the road friction resistance, taking only road composition and making measurements in wet conditions into account. However, friction forces are also dependent on the tire type, since the contact is established between the tire and the road in real driving conditions. Thus, the type and characteristics of the tire have to be considered in the study of the interaction between the vehicle and the road. The aim of this work is to unify the study of the friction coefficient, taking into consideration the two existing bodies involved in the contact, i.e., the tire and road and the main factors that influence the forces in the contact. To this end, a modification of the Pacejka Magic Formula is proposed to include the effects of the main parameters that influence the contact, such as road composition and its state, tire type, vehicle speed, and slip between the tire and the road. To do so, real tests have been conducted on several roads and with different operating conditions. As a result, a more accurate tire-road friction model has been obtained.

  11. Surgery for constipation: systematic review and practice recommendations: Results II: Hitching procedures for the rectum (rectal suspension).

    Science.gov (United States)

    Grossi, U; Knowles, C H; Mason, J; Lacy-Colson, J; Brown, S R

    2017-09-01

    To assess the outcomes of rectal suspension procedures (forms of rectopexy) in adults with chronic constipation. Standardised methods and reporting of benefits and harms were used for all CapaCiTY reviews that closely adhered to PRISMA 2016 guidance. Main conclusions were presented as summary evidence statements with a summative Oxford Centre for Evidence-Based Medicine (2009) level. Eighteen articles were identified, providing data on outcomes in 1238 patients. All studies reported only on laparoscopic approaches. Length of procedures ranged between 1.5 to 3.5 h, and length of stay between 4 to 5 days. Data on harms were inconsistently reported and heterogeneous, making estimates of harm tentative and imprecise. Morbidity rates ranged between 5-15%, with mesh complications accounting for 0.5% of patients overall. No mortality was reported after any procedures in a total of 1044 patients. Although inconsistently reported, good or satisfactory outcome occurred in 83% (74-91%) of patients; 86% (20-97%) of patients reported improvements in constipation after laparoscopic ventral mesh rectopexy (LVMR). About 2-7% of patients developed anatomical recurrence. Patient selection was inconsistently documented. As most common indication, high grade rectal intussusception was corrected in 80-100% of cases after robotic or LVMR. Healing of prolapse-associated solitary rectal ulcer syndrome occurred in around 80% of patients after LVMR. Evidence supporting rectal suspension procedures is currently derived from poor quality studies. Methodologically robust trials are needed to inform future clinical decision making. © 2017 The Authors. Colorectal Disease published by John Wiley & Sons Ltd on behalf of Association of Coloproctology of Great Britain and Ireland.

  12. The impact of obesity on pediatric procedural sedation-related outcomes: results from the Pediatric Sedation Research Consortium.

    Science.gov (United States)

    Scherrer, Patricia D; Mallory, Michael D; Cravero, Joseph P; Lowrie, Lia; Hertzog, James H; Berkenbosch, John W

    2015-07-01

    To evaluate the impact of obesity on adverse events and required interventions during pediatric procedural sedation. The Pediatric Sedation Research Consortium database of prospectively collected procedural sedation encounters was queried to identify patients for whom body mass index (BMI) could be calculated. Obesity was defined as BMI ≥95th percentile for age and gender. Sedation-related outcomes, adverse events, and therapeutic interventions were compared between obese and nonobese patients. For analysis, 28,792 records were eligible. A total of 5,153 patients (17.9%) were obese; they were predominantly male and older and had a higher median American Society of Anesthesiologists Physical Status classification (P obese patients (odds ratio [OR] 1.49, 95% confidence interval [1.31, 1.70]). Respiratory events (airway obstruction OR 1.94 [1.54, 2.44], oxygen desaturation OR 1.99 [1.50, 2.63], secretions OR 1.48 [1.01, 2.15], laryngospasm OR 2.30 [1.30, 4.05]), inability to complete the associated procedure (OR 1.96 [1.16, 3.30]), and prolonged recovery (OR 2.66 [1.26, 5.59]) were increased in obese patients. Obese patients more frequently required airway intervention including repositioning, suctioning, jaw thrust, airway adjuncts, and bag-valve-mask ventilation. Multivariate regression analysis demonstrated obesity to be independently associated with minor and moderate but not major adverse events. Obesity is an independent risk factor for adverse respiratory events during procedural sedation and is associated with an increased frequency of airway interventions, suggesting that additional vigilance and expertise are required when sedating these patients. © 2015 John Wiley & Sons Ltd.

  13. Initial CGE Model Results Summary Exogenous and Endogenous Variables Tests

    Energy Technology Data Exchange (ETDEWEB)

    Edwards, Brian Keith [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Boero, Riccardo [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Rivera, Michael Kelly [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-08-07

    The following discussion presents initial results of tests of the most recent version of the National Infrastructure Simulation and Analysis Center Dynamic Computable General Equilibrium (CGE) model developed by Los Alamos National Laboratory (LANL). The intent of this is to test and assess the model’s behavioral properties. The test evaluated whether the predicted impacts are reasonable from a qualitative perspective. This issue is whether the predicted change, be it an increase or decrease in other model variables, is consistent with prior economic intuition and expectations about the predicted change. One of the purposes of this effort is to determine whether model changes are needed in order to improve its behavior qualitatively and quantitatively.

  14. Developing a spatial-statistical model and map of historical malaria prevalence in Botswana using a staged variable selection procedure

    Directory of Open Access Journals (Sweden)

    Mabaso Musawenkosi LH

    2007-09-01

    Full Text Available Abstract Background Several malaria risk maps have been developed in recent years, many from the prevalence of infection data collated by the MARA (Mapping Malaria Risk in Africa project, and using various environmental data sets as predictors. Variable selection is a major obstacle due to analytical problems caused by over-fitting, confounding and non-independence in the data. Testing and comparing every combination of explanatory variables in a Bayesian spatial framework remains unfeasible for most researchers. The aim of this study was to develop a malaria risk map using a systematic and practicable variable selection process for spatial analysis and mapping of historical malaria risk in Botswana. Results Of 50 potential explanatory variables from eight environmental data themes, 42 were significantly associated with malaria prevalence in univariate logistic regression and were ranked by the Akaike Information Criterion. Those correlated with higher-ranking relatives of the same environmental theme, were temporarily excluded. The remaining 14 candidates were ranked by selection frequency after running automated step-wise selection procedures on 1000 bootstrap samples drawn from the data. A non-spatial multiple-variable model was developed through step-wise inclusion in order of selection frequency. Previously excluded variables were then re-evaluated for inclusion, using further step-wise bootstrap procedures, resulting in the exclusion of another variable. Finally a Bayesian geo-statistical model using Markov Chain Monte Carlo simulation was fitted to the data, resulting in a final model of three predictor variables, namely summer rainfall, mean annual temperature and altitude. Each was independently and significantly associated with malaria prevalence after allowing for spatial correlation. This model was used to predict malaria prevalence at unobserved locations, producing a smooth risk map for the whole country. Conclusion We have

  15. Interaction between subducting plates: results from numerical and analogue modeling

    Science.gov (United States)

    Kiraly, Agnes; Capitanio, Fabio A.; Funiciello, Francesca; Faccenna, Claudio

    2016-04-01

    The tectonic setting of the Alpine-Mediterranean area is achieved during the late Cenozoic subduction, collision and suturing of several oceanic fragments and continental blocks. In this stage, processes such as interactions among subducting slabs, slab migrations and related mantle flow played a relevant role on the resulting tectonics. Here, we use numerical models to first address the mantle flow characteristic in 3D. During the subduction of a single plate the strength of the return flow strongly depends on the slab pull force, that is on the plate's buoyancy, however the physical properties of the slab, such as density, viscosity or width, do not affect largely the morphology of the toroidal cell. Instead, dramatic effects on the geometry and the dynamics of the toroidal cell result in models where the thickness of the mantle is varied. The vertical component of the vorticity vector is used to define the characteristic size of the toroidal cell, which is ~1.2-1.3 times the mantle depth. This latter defines the range of viscous stress propagation through the mantle and consequent interactions with other slabs. We thus further investigate on this setup where two separate lithospheric plates subduct in opposite sense, developing opposite polarities and convergent slab retreat, and model different initial sideways distance between the plates. The stress profiles in time illustrate that the plates interacts when slabs are at the characteristic distance and the two slabs toroidal cells merge. Increased stress and delayed slab migrations are the results. Analogue models of double-sided subduction show similar maximum distance and allow testing the additional role of stress propagated through the plates. We use a silicon plate subducting on its two opposite margins, which is either homogeneous or comprises oceanic and continental lithospheres, differing in buoyancy. The modeling results show that the double-sided subduction is strongly affected by changes in plate

  16. First experiments results about the engineering model of Rapsodie

    International Nuclear Information System (INIS)

    Chalot, A.; Ginier, R.; Sauvage, M.

    1964-01-01

    This report deals with the first series of experiments carried out on the engineering model of Rapsodie and on an associated sodium facility set in a laboratory hall of Cadarache. It conveys more precisely: 1/ - The difficulties encountered during the erection and assembly of the engineering model and a compilation of the results of the first series of experiments and tests carried out on this installation (loading of the subassemblies preheating, thermal chocks...). 2/ - The experiments and tests carried out on the two prototypes control rod drive mechanisms which brought to the choice for the design of the definitive drive mechanism. As a whole, the results proved the validity of the general design principles adopted for Rapsodie. (authors) [fr

  17. Workshop to transfer VELMA watershed model results to ...

    Science.gov (United States)

    An EPA Western Ecology Division (WED) watershed modeling team has been working with the Snoqualmie Tribe Environmental and Natural Resources Department to develop VELMA watershed model simulations of the effects of historical and future restoration and land use practices on streamflow, stream temperature, and other habitat characteristics affecting threatened salmon populations in the 100 square mile Tolt River watershed in Washington state. To date, the WED group has fully calibrated the watershed model to simulate Tolt River flows with a high degree of accuracy under current and historical conditions and practices, and is in the process of simulating long-term responses to specific watershed restoration practices conducted by the Snoqualmie Tribe and partners. On July 20-21 WED Researchers Bob McKane, Allen Brookes and ORISE Fellow Jonathan Halama will be attending a workshop at the Tolt River site in Carnation, WA, to present and discuss modeling results with the Snoqualmie Tribe and other Tolt River watershed stakeholders and land managers, including the Washington Departments of Ecology and Natural Resources, U.S. Forest Service, City of Seattle, King County, and representatives of the Northwest Indian Fisheries Commission. The workshop is being co-organized by the Snoqualmie Tribe, EPA Region 10 and WED. The purpose of this 2-day workshop is two-fold. First, on Day 1, the modeling team will perform its second site visit to the watershed, this time focus

  18. Meteorological uncertainty of atmospheric dispersion model results (MUD)

    International Nuclear Information System (INIS)

    Havskov Soerensen, J.; Amstrup, B.; Feddersen, H.

    2013-08-01

    The MUD project addresses assessment of uncertainties of atmospheric dispersion model predictions, as well as possibilities for optimum presentation to decision makers. Previously, it has not been possible to estimate such uncertainties quantitatively, but merely to calculate the 'most likely' dispersion scenario. However, recent developments in numerical weather prediction (NWP) include probabilistic forecasting techniques, which can be utilised also for long-range atmospheric dispersion models. The ensemble statistical methods developed and applied to NWP models aim at describing the inherent uncertainties of the meteorological model results. These uncertainties stem from e.g. limits in meteorological observations used to initialise meteorological forecast series. By perturbing e.g. the initial state of an NWP model run in agreement with the available observational data, an ensemble of meteorological forecasts is produced from which uncertainties in the various meteorological parameters are estimated, e.g. probabilities for rain. Corresponding ensembles of atmospheric dispersion can now be computed from which uncertainties of predicted radionuclide concentration and deposition patterns can be derived. (Author)

  19. Some results on hyperscaling in the 3D Ising model

    Energy Technology Data Exchange (ETDEWEB)

    Baker, G.A. Jr. [Los Alamos National Lab., NM (United States). Theoretical Div.; Kawashima, Naoki [Univ. of Tokyo (Japan). Dept. of Physics

    1995-09-01

    The authors review exact studies on finite-sized 2 dimensional Ising models and show that the point for an infinite-sized model at the critical temperature is a point of nonuniform approach in the temperature-size plane. They also illuminate some strong effects of finite-size on quantities which do not diverge at the critical point. They then review Monte Carlo studies for 3 dimensional Ising models of various sizes (L = 2--100) at various temperatures. From these results they find that the data for the renormalized coupling constant collapses nicely when plotted against the correlation length, determined in a system of edge length L, divided by L. They also find that {zeta}{sub L}/L {ge} 0.26 is definitely too large for reliable studies of the critical value, g*, of the renormalized coupling constant. They have reasonable evidence that {zeta}{sub L}/L {approx} 0.1 is adequate for results that are within one percent of those for the infinite system size. On this basis, they have conducted a series of Monte Carlo calculations with this condition imposed. These calculations were made practical by the development of improved estimators for use in the Swendsen-Wang cluster method. The authors found from these results, coupled with a reversed limit computation (size increases with the temperature fixed at the critical temperature), that g* > 0, although there may well be a sharp downward drop in g as the critical temperature is approached in accord with the predictions of series analysis. The results support the validity of hyperscaling in the 3 dimensional Ising model.

  20. Presenting results of software model checker via debugging interface

    OpenAIRE

    Kohan, Tomáš

    2012-01-01

    Title: Presenting results of software model checker via debugging interface Author: Tomáš Kohan Department: Department of Software Engineering Supervisor of the master thesis: RNDr. Ondřej Šerý, Ph.D., Department of Distributed and Dependable Systems Abstract: This thesis is devoted to design and implementation of the new debugging interface of the Java PathFinder application. As a suitable inte- face container was selected the Eclipse development environment. The created interface should vis...

  1. Inter-model, analytical, and experimental validation of a heat balance based residential cooling load calculation procedure

    Science.gov (United States)

    Xiao, Dongyi

    Scope and method of study. A systematic validation of the ASHRAE heat balance based residential cooling load calculation procedure (RHB) has been performed with inter-model comparison, analytical verification and experimental validation. The inter-model validation was performed using ESP-r as the reference model. The testing process was automated through parametric generation and simulation of large sets of test cases for both RHB and ESP-r. The house prototypes covered include a simple Shoebox prototype and a real 4-bedroom house prototype. An analytical verification test suite for building fabric models of whole building energy simulation programs has been developed. The test suite consists of a series of sixteen tests covering convection, conduction, solar irradiation, long-wave radiation, infiltration and ground-coupled floors. Using the test suite, a total of twelve analytical tests have been done with the RHB procedure. The experimental validation has been conducted using experimental data collected from a Cardinal Project house located in Fort Wayne, Indiana. During the diagnostic process of the experimental validation, comparisons have also been made between ESP-r simulation results and experimental data. Findings and conclusions. It is concluded RHB is acceptable as a design tool on a typical North American house. Analytical tests confirmed the underlying mechanisms for modeling basic heat transfer phenomena in building fabric. The inter-model comparison showed that the differences found between RHB and ESP-r can be traced to the differences in sub-models used by RHB and ESP-r. It also showed that the RHB-designed systems can meet the design criteria and that the RHB temperature swing option is helpful in reducing system over-sizing. The experimental validation demonstrated that the systems designed with the method will have adequate size to meet the room temperatures specified in the design, whether or not swing is utilized. However, actual system

  2. Adverse events related to gastrointestinal endoscopic procedures in pediatric patients under anesthesia care and a predictive risk model (AEGEP Study).

    Science.gov (United States)

    Ariza, F; Montilla-Coral, D; Franco, O; González, L F; Lozano, L C; Torres, A M; Jordán, J; Blanco, L F; Suárez, L; Cruz, G; Cepeda, M

    2014-01-01

    Multiple studies have analyzed perioperative factors related to adverse events (AEs) in children who require gastrointestinal endoscopic procedures (GEP) in settings where deep sedation is the preferred anesthetic technique over general anesthesia (GA) but not for the opposite case. We reviewed our anesthesia institutional database, seeking children less than 12 years who underwent GEP over a 5-year period. A logistic regression was used to determine significant associations between preoperative conditions, characteristics of the procedure, airway management, anesthetic approaches and the presence of serious and non-serious AEs. GA was preferred over deep sedation [77.8% vs. 22.2% in 2178 GEP under anesthesia care (n=1742)]. We found 96 AEs reported in 77 patients, including hypoxemia (1.82%), bronchospasm (1.14%) and laryngospasm (0.91%) as the most frequent. There were 2 cases of severe bradycardia related to laryngospasm/hypoxemia and a case of aspiration resulting in unplanned hospitalization, but there were no cases of intra- or postoperative deaths. Final predictive model for perioperative AEs included age <1 year, upper respiratory tract infections (URTI) <1 week prior to the procedure and low weight for the age (LWA) as independent risk factors and ventilation by facial mask as a protector against these events (p<0.05). AEs are infrequent and severe ones are remote in a setting where AG is preferred over deep sedation. Ventilatory AEs are the most frequent and depend on biometrical and comorbid conditions more than anesthetic drugs chosen. Age <1 year, history of URTI in the week prior to the procedure and LWA work as independent risk factors for AEs in these patients. Copyright © 2013 Sociedad Española de Anestesiología, Reanimación y Terapéutica del Dolor. Published by Elsevier España. All rights reserved.

  3. Review of Current Standard Model Results in ATLAS

    CERN Document Server

    Brandt, Gerhard; The ATLAS collaboration

    2018-01-01

    This talk highlights results selected from the Standard Model research programme of the ATLAS Collaboration at the Large Hadron Collider. Results using data from $p-p$ collisions at $\\sqrt{s}=7,8$~TeV in LHC Run-1 as well as results using data at $\\sqrt{s}=13$~TeV in LHC Run-2 are covered. The status of cross section measurements from soft QCD processes and jet production as well as photon production are presented. The presentation extends to vector boson production with associated jets. Precision measurements of the production of $W$ and $Z$ bosons, including a first measurement of the mass of the $W$ bosons, $m_W$, are discussed. The programme to measure electroweak processes with di-boson and tri-boson final states is outlined. All presented measurements are compatible with Standard Model descriptions and allow to further constrain it. In addition they allow to probe new physics which would manifest through extra gauge couplings, or Standard Model gauge couplings deviating from their predicted value.

  4. A Spatial Allocation Procedure to Downscale Regional Crop Production Estimates from an Integrated Assessment Model

    Science.gov (United States)

    Moulds, S.; Djordjevic, S.; Savic, D.

    2017-12-01

    The Global Change Assessment Model (GCAM), an integrated assessment model, provides insight into the interactions and feedbacks between physical and human systems. The land system component of GCAM, which simulates land use activities and the production of major crops, produces output at the subregional level which must be spatially downscaled in order to use with gridded impact assessment models. However, existing downscaling routines typically consider cropland as a homogeneous class and do not provide information about land use intensity or specific management practices such as irrigation and multiple cropping. This paper presents a spatial allocation procedure to downscale crop production data from GCAM to a spatial grid, producing a time series of maps which show the spatial distribution of specific crops (e.g. rice, wheat, maize) at four input levels (subsistence, low input rainfed, high input rainfed and high input irrigated). The model algorithm is constrained by available cropland at each time point and therefore implicitly balances extensification and intensification processes in order to meet global food demand. It utilises a stochastic approach such that an increase in production of a particular crop is more likely to occur in grid cells with a high biophysical suitability and neighbourhood influence, while a fall in production will occur more often in cells with lower suitability. User-supplied rules define the order in which specific crops are downscaled as well as allowable transitions. A regional case study demonstrates the ability of the model to reproduce historical trends in India by comparing the model output with district-level agricultural inventory data. Lastly, the model is used to predict the spatial distribution of crops globally under various GCAM scenarios.

  5. Improving the Prediction of Total Surgical Procedure Time Using Linear Regression Modeling

    Directory of Open Access Journals (Sweden)

    Eric R. Edelman

    2017-06-01

    Full Text Available For efficient utilization of operating rooms (ORs, accurate schedules of assigned block time and sequences of patient cases need to be made. The quality of these planning tools is dependent on the accurate prediction of total procedure time (TPT per case. In this paper, we attempt to improve the accuracy of TPT predictions by using linear regression models based on estimated surgeon-controlled time (eSCT and other variables relevant to TPT. We extracted data from a Dutch benchmarking database of all surgeries performed in six academic hospitals in The Netherlands from 2012 till 2016. The final dataset consisted of 79,983 records, describing 199,772 h of total OR time. Potential predictors of TPT that were included in the subsequent analysis were eSCT, patient age, type of operation, American Society of Anesthesiologists (ASA physical status classification, and type of anesthesia used. First, we computed the predicted TPT based on a previously described fixed ratio model for each record, multiplying eSCT by 1.33. This number is based on the research performed by van Veen-Berkx et al., which showed that 33% of SCT is generally a good approximation of anesthesia-controlled time (ACT. We then systematically tested all possible linear regression models to predict TPT using eSCT in combination with the other available independent variables. In addition, all regression models were again tested without eSCT as a predictor to predict ACT separately (which leads to TPT by adding SCT. TPT was most accurately predicted using a linear regression model based on the independent variables eSCT, type of operation, ASA classification, and type of anesthesia. This model performed significantly better than the fixed ratio model and the method of predicting ACT separately. Making use of these more accurate predictions in planning and sequencing algorithms may enable an increase in utilization of ORs, leading to significant financial and productivity related

  6. Improving the Prediction of Total Surgical Procedure Time Using Linear Regression Modeling.

    Science.gov (United States)

    Edelman, Eric R; van Kuijk, Sander M J; Hamaekers, Ankie E W; de Korte, Marcel J M; van Merode, Godefridus G; Buhre, Wolfgang F F A

    2017-01-01

    For efficient utilization of operating rooms (ORs), accurate schedules of assigned block time and sequences of patient cases need to be made. The quality of these planning tools is dependent on the accurate prediction of total procedure time (TPT) per case. In this paper, we attempt to improve the accuracy of TPT predictions by using linear regression models based on estimated surgeon-controlled time (eSCT) and other variables relevant to TPT. We extracted data from a Dutch benchmarking database of all surgeries performed in six academic hospitals in The Netherlands from 2012 till 2016. The final dataset consisted of 79,983 records, describing 199,772 h of total OR time. Potential predictors of TPT that were included in the subsequent analysis were eSCT, patient age, type of operation, American Society of Anesthesiologists (ASA) physical status classification, and type of anesthesia used. First, we computed the predicted TPT based on a previously described fixed ratio model for each record, multiplying eSCT by 1.33. This number is based on the research performed by van Veen-Berkx et al., which showed that 33% of SCT is generally a good approximation of anesthesia-controlled time (ACT). We then systematically tested all possible linear regression models to predict TPT using eSCT in combination with the other available independent variables. In addition, all regression models were again tested without eSCT as a predictor to predict ACT separately (which leads to TPT by adding SCT). TPT was most accurately predicted using a linear regression model based on the independent variables eSCT, type of operation, ASA classification, and type of anesthesia. This model performed significantly better than the fixed ratio model and the method of predicting ACT separately. Making use of these more accurate predictions in planning and sequencing algorithms may enable an increase in utilization of ORs, leading to significant financial and productivity related benefits.

  7. Challenges in validating model results for first year ice

    Science.gov (United States)

    Melsom, Arne; Eastwood, Steinar; Xie, Jiping; Aaboe, Signe; Bertino, Laurent

    2017-04-01

    In order to assess the quality of model results for the distribution of first year ice, a comparison with a product based on observations from satellite-borne instruments has been performed. Such a comparison is not straightforward due to the contrasting algorithms that are used in the model product and the remote sensing product. The implementation of the validation is discussed in light of the differences between this set of products, and validation results are presented. The model product is the daily updated 10-day forecast from the Arctic Monitoring and Forecasting Centre in CMEMS. The forecasts are produced with the assimilative ocean prediction system TOPAZ. Presently, observations of sea ice concentration and sea ice drift are introduced in the assimilation step, but data for sea ice thickness and ice age (or roughness) are not included. The model computes the age of the ice by recording and updating the time passed after ice formation as sea ice grows and deteriorates as it is advected inside the model domain. Ice that is younger than 365 days is classified as first year ice. The fraction of first-year ice is recorded as a tracer in each grid cell. The Ocean and Sea Ice Thematic Assembly Centre in CMEMS redistributes a daily product from the EUMETSAT OSI SAF of gridded sea ice conditions which include "ice type", a representation of the separation of regions between those infested by first year ice, and those infested by multi-year ice. The ice type is parameterized based on data for the gradient ratio GR(19,37) from SSMIS observations, and from the ASCAT backscatter parameter. This product also includes information on ambiguity in the processing of the remote sensing data, and the product's confidence level, which have a strong seasonal dependency.

  8. Thermal-Chemical Model Of Subduction: Results And Tests

    Science.gov (United States)

    Gorczyk, W.; Gerya, T. V.; Connolly, J. A.; Yuen, D. A.; Rudolph, M.

    2005-12-01

    Seismic structures with strong positive and negative velocity anomalies in the mantle wedge above subduction zones have been interpreted as thermally and/or chemically induced phenomena. We have developed a thermal-chemical model of subduction, which constrains the dynamics of seismic velocity structure beneath volcanic arcs. Our simulations have been calculated over a finite-difference grid with (201×101) to (201×401) regularly spaced Eulerian points, using 0.5 million to 10 billion markers. The model couples numerical thermo-mechanical solution with Gibbs energy minimization to investigate the dynamic behavior of partially molten upwellings from slabs (cold plumes) and structures associated with their development. The model demonstrates two chemically distinct types of plumes (mixed and unmixed), and various rigid body rotation phenomena in the wedge (subduction wheel, fore-arc spin, wedge pin-ball). These thermal-chemical features strongly perturb seismic structure. Their occurrence is dependent on the age of subducting slab and the rate of subduction.The model has been validated through a series of test cases and its results are consistent with a variety of geological and geophysical data. In contrast to models that attribute a purely thermal origin for mantle wedge seismic anomalies, the thermal-chemical model is able to simulate the strong variations of seismic velocity existing beneath volcanic arcs which are associated with development of cold plumes. In particular, molten regions that form beneath volcanic arcs as a consequence of vigorous cold wet plumes are manifest by > 20% variations in the local Poisson ratio, as compared to variations of ~ 2% expected as a consequence of temperature variation within the mantle wedge.

  9. Measurement model choice influenced randomized controlled trial results.

    Science.gov (United States)

    Gorter, Rosalie; Fox, Jean-Paul; Apeldoorn, Adri; Twisk, Jos

    2016-11-01

    In randomized controlled trials (RCTs), outcome variables are often patient-reported outcomes measured with questionnaires. Ideally, all available item information is used for score construction, which requires an item response theory (IRT) measurement model. However, in practice, the classical test theory measurement model (sum scores) is mostly used, and differences between response patterns leading to the same sum score are ignored. The enhanced differentiation between scores with IRT enables more precise estimation of individual trajectories over time and group effects. The objective of this study was to show the advantages of using IRT scores instead of sum scores when analyzing RCTs. Two studies are presented, a real-life RCT, and a simulation study. Both IRT and sum scores are used to measure the construct and are subsequently used as outcomes for effect calculation. The bias in RCT results is conditional on the measurement model that was used to construct the scores. A bias in estimated trend of around one standard deviation was found when sum scores were used, where IRT showed negligible bias. Accurate statistical inferences are made from an RCT study when using IRT to estimate construct measurements. The use of sum scores leads to incorrect RCT results. Copyright © 2016 Elsevier Inc. All rights reserved.

  10. Clinical use of a 15-W diode laser in small animal surgery: results in 30 varied procedures

    Science.gov (United States)

    Crowe, Dennis T.; Swalander, David; Hittenmiller, Donald; Newton, Jenifer

    1999-06-01

    The use of a 15-watt diode laser (CeramOptec)in 30 surgical procedures in dogs and cats was reviewed. Ease of use, operator safety, hemostasis control, wound healing, surgical time, complication rate, and pain control were observed and recorded. Procedures performed were partial pancreatectomy, nasal carcinoma ablation, medial meniscus channeling, perianal and anorectal mass removal (5), hemangioma and hemangiopericytoma removal from two legs, benign skin mass removal (7), liver lobectomy, partial prostatectomy, soft palate resection, partial arytenoidectomy, partial ablation of a thyroid carcinoma, photo-vaporization of the tumor bed following malignant tumor resection (4), neurosheath tumor removal from the tongue, tail sebaceous cyst resection, malignant mammary tumor and mast cell tumor removal. The laser was found to be very simple and safe to use. Hemostasis was excellent in all but the liver and prostate surgeries. The laser was particularly effective in preventing hemorrhage during perianal, anal, and tongue mass removal. It is estimated that a time and blood loss savings of 50% over that of conventional surgery occurred with the use of the laser. All external wounds made by laser appeared to heal faster and with less inflammation than those made with a conventional or electrosurgical scalpel.

  11. Combining Decision Diagrams and SAT Procedures for Efficient Symbolic Model Checking

    DEFF Research Database (Denmark)

    Williams, Poul Frederick; Biere, Armin; Clarke, Edmund M.

    2000-01-01

    , combined with BDDs and SAT-solvers to perform satisfiability checking. As a result we are able to model check systems for which standard BDD-based methods fail. For example, we model check a liveness property of a 256 bit shift-and-add multiplier and we are able to find a previously undetected bug...

  12. An Effective Procedure for Training Early Special Education Teams to Implement a Model Program.

    Science.gov (United States)

    Rogers, Sally J.; And Others

    1987-01-01

    Training of early special education teams (serving 11 autistic and 10 developmentally-delayed children) to use the Playschool model resulted in: positive perception of the training's value; increases in knowledge about child development, infantile autism, and the model; increased use of Playschool techniques; and positive developmental changes in…

  13. Loss of spent fuel pool cooling PRA: Model and results

    Energy Technology Data Exchange (ETDEWEB)

    Siu, N.; Khericha, S.; Conroy, S.; Beck, S.; Blackman, H.

    1996-09-01

    This letter report documents models for quantifying the likelihood of loss of spent fuel pool cooling; models for identifying post-boiling scenarios that lead to core damage; qualitative and quantitative results generated for a selected plant that account for plant design and operational practices; a comparison of these results and those generated from earlier studies; and a review of available data on spent fuel pool accidents. The results of this study show that for a representative two-unit boiling water reactor, the annual probability of spent fuel pool boiling is 5 {times} 10{sup {minus}5} and the annual probability of flooding associated with loss of spent fuel pool cooling scenarios is 1 {times} 10{sup {minus}3}. Qualitative arguments are provided to show that the likelihood of core damage due to spent fuel pool boiling accidents is low for most US commercial nuclear power plants. It is also shown that, depending on the design characteristics of a given plant, the likelihood of either: (a) core damage due to spent fuel pool-associated flooding, or (b) spent fuel damage due to pool dryout, may not be negligible.

  14. SR-Site groundwater flow modelling methodology, setup and results

    Energy Technology Data Exchange (ETDEWEB)

    Selroos, Jan-Olof (Swedish Nuclear Fuel and Waste Management Co., Stockholm (Sweden)); Follin, Sven (SF GeoLogic AB, Taeby (Sweden))

    2010-12-15

    As a part of the license application for a final repository for spent nuclear fuel at Forsmark, the Swedish Nuclear Fuel and Waste Management Company (SKB) has undertaken three groundwater flow modelling studies. These are performed within the SR-Site project and represent time periods with different climate conditions. The simulations carried out contribute to the overall evaluation of the repository design and long-term radiological safety. Three time periods are addressed; the Excavation and operational phases, the Initial period of temperate climate after closure, and the Remaining part of the reference glacial cycle. The present report is a synthesis of the background reports describing the modelling methodology, setup, and results. It is the primary reference for the conclusions drawn in a SR-Site specific context concerning groundwater flow during the three climate periods. These conclusions are not necessarily provided explicitly in the background reports, but are based on the results provided in these reports. The main results and comparisons presented in the present report are summarised in the SR-Site Main report.

  15. Loss of spent fuel pool cooling PRA: Model and results

    International Nuclear Information System (INIS)

    Siu, N.; Khericha, S.; Conroy, S.; Beck, S.; Blackman, H.

    1996-09-01

    This letter report documents models for quantifying the likelihood of loss of spent fuel pool cooling; models for identifying post-boiling scenarios that lead to core damage; qualitative and quantitative results generated for a selected plant that account for plant design and operational practices; a comparison of these results and those generated from earlier studies; and a review of available data on spent fuel pool accidents. The results of this study show that for a representative two-unit boiling water reactor, the annual probability of spent fuel pool boiling is 5 x 10 -5 and the annual probability of flooding associated with loss of spent fuel pool cooling scenarios is 1 x 10 -3 . Qualitative arguments are provided to show that the likelihood of core damage due to spent fuel pool boiling accidents is low for most US commercial nuclear power plants. It is also shown that, depending on the design characteristics of a given plant, the likelihood of either: (a) core damage due to spent fuel pool-associated flooding, or (b) spent fuel damage due to pool dryout, may not be negligible

  16. Are joint and soft tissue injections painful? Results of a national French cross-sectional study of procedural pain in rheumatological practice

    Directory of Open Access Journals (Sweden)

    Poncet Coralie

    2010-01-01

    Full Text Available Abstract Background Joint, spinal and soft tissue injections are commonly performed by rheumatologists in their daily practice. Contrary to other procedures, e.g. performed in pediatric care, little is known about the frequency, the intensity and the management of procedural pain observed in osteo-articular injections in daily practice. Methods This observational, prospective, national study was carried out among a French national representative database of primary rheumatologists to evaluate the prevalence and intensity of pain caused by intra-and peri-articular injections, synovial fluid aspirations, soft tissue injections, and spinal injections. For each physician, data were collected over 1 month, for up to 40 consecutive patients (>18-years-old for whom a synovial fluid aspiration, an intra or peri-articular injection or a spinal injection were carried out during consultations. Statistical analysis was carried out in order to compare patients who had suffered from pain whilst undergoing the procedure to those who had not. Explanatory analyses were conducted by stepwise logistic regression with the characteristics of the patients to explain the existence of pain. Results Data were analysed for 8446 patients (64% female, mean age 62 ± 14 years recruited by 240 physicians. The predominant sites injected were the knee (45.5% and spine (19.1%. Over 80% of patients experienced procedural pain which was most common in the small joints (42% and spine (32% Pain was severe in 5.3% of patients, moderate in 26.6%, mild in 49.8%, and absent in 18.3%. Pain was significantly more intense in patients with severe pain linked to their underlying pathology and for procedures performed in small joints. Preventative or post-procedure analgesia was rarely given, only to 5.7% and 36.3% of patients, respectively. Preventative analgesia was more frequently prescribed in patients with more severe procedural pain. Conclusion Most patients undergoing intra-or peri

  17. Prediction of melting temperatures in fluorescence in situ hybridization (FISH) procedures using thermodynamic models.

    Science.gov (United States)

    Fontenete, Sílvia; Guimarães, Nuno; Wengel, Jesper; Azevedo, Nuno Filipe

    2016-01-01

    The thermodynamics and kinetics of DNA hybridization, i.e. the process of self-assembly of one, two or more complementary nucleic acid strands, has been studied for many years. The appearance of the nearest-neighbor model led to several theoretical and experimental papers on DNA thermodynamics that provide reasonably accurate thermodynamic information on nucleic acid duplexes and allow estimation of the melting temperature. Because there are no thermodynamic models specifically developed to predict the hybridization temperature of a probe used in a fluorescence in situ hybridization (FISH) procedure, the melting temperature is used as a reference, together with corrections for certain compounds that are used during FISH. However, the quantitative relation between melting and experimental FISH temperatures is poorly described. In this review, various models used to predict the melting temperature for rRNA targets, for DNA oligonucleotides and for nucleic acid mimics (chemically modified oligonucleotides), will be addressed in detail, together with a critical assessment of how this information should be used in FISH.

  18. A Novel Murine Model of Arteriovenous Fistula Failure: The Surgical Procedure in Detail.

    Science.gov (United States)

    Wong, Chun Yu; de Vries, Margreet R; Wang, Yang; van der Vorst, Joost R; Vahrmeijer, Alexander L; van Zonneveld, Anton-Jan; Hamming, Jaap F; Roy-Chaudhury, Prabir; Rabelink, Ton J; Quax, Paul H A; Rotmans, Joris I

    2016-02-03

    The arteriovenous fistula (AVF) still suffers from a high number of failures caused by insufficient remodeling and intimal hyperplasia from which the exact pathophysiology remains unknown. In order to unravel the pathophysiology a murine model of AVF-failure was developed in which the configuration of the anastomosis resembles the preferred situation in the clinical setting. A model was described in which an AVF is created by connecting the venous end of the branch of the external jugular vein to the side of the common carotid artery using interrupted sutures. At a histological level, we observed progressive stenotic intimal lesions in the venous outflow tract that is also seen in failed human AVFs. Although this procedure can be technically challenging due to the small dimensions of the animal, we were able to achieve a surgical success rate of 97% after sufficient training. The key advantage of a murine model is the availability of transgenic animals. In view of the different proposed mechanisms that are responsible for AVF failure, disabling genes that might play a role in vascular remodeling can help us to unravel the complex pathophysiology of AVF failure.

  19. A Novel Murine Model of Arteriovenous Fistula Failure: The Surgical Procedure in Detail

    Science.gov (United States)

    Wong, Chun Yu; de Vries, Margreet R.; Wang, Yang; van der Vorst, Joost R.; Vahrmeijer, Alexander L.; van Zonneveld, Anton-Jan; Hamming, Jaap F.; Roy-Chaudhury, Prabir; Rabelink, Ton J.; Quax, Paul H. A.; Rotmans, Joris I.

    2016-01-01

    The arteriovenous fistula (AVF) still suffers from a high number of failures caused by insufficient remodeling and intimal hyperplasia from which the exact pathophysiology remains unknown. In order to unravel the pathophysiology a murine model of AVF-failure was developed in which the configuration of the anastomosis resembles the preferred situation in the clinical setting. A model was described in which an AVF is created by connecting the venous end of the branch of the external jugular vein to the side of the common carotid artery using interrupted sutures. At a histological level, we observed progressive stenotic intimal lesions in the venous outflow tract that is also seen in failed human AVFs. Although this procedure can be technically challenging due to the small dimensions of the animal, we were able to achieve a surgical success rate of 97% after sufficient training. The key advantage of a murine model is the availability of transgenic animals. In view of the different proposed mechanisms that are responsible for AVF failure, disabling genes that might play a role in vascular remodeling can help us to unravel the complex pathophysiology of AVF failure. PMID:26863177

  20. Search procedure for models based on the evolution of experimental curves

    International Nuclear Information System (INIS)

    Delforge, J.

    1975-01-01

    The possibilities offered by numerical analysis regarding the identification of parameters for the model are outlined. The use of a large number of experimental measurements is made possible by the flexibility of the proposed method. It is shown that the errors of numerical identification over all parameters are proportional to experimental errors, and to a proportionality factor called conditioning of the identification problem which is easily computed. Moreover, it is possible to define and calculate, for each parameter, a factor of sensitivity to experimental errors. The numerical values of conditioning and sensitivity factor depend on all experimental conditions, that is, on the one hand, the specific definition of the experiments, and on the other hand, the number and quality of the undertaken measurements. The identification procedure proposed includes several phases. The preliminary phase consists in a first definition of experimental conditions, in agreement with the experimenter. From the data thus obtained, it is generally possible to evaluate the minimum number of equivalence classes required for an interpretation compatible with the morphology of experimental curves. Possibly, from this point, some additional measurements may prove useful or required. The numerical phase comes afterwards to determine a first approximate model by means of the methods previously described. Next phases again require a close collaboration between experimenters and theoreticians. They consist mainly in refining the first model [fr

  1. Results of the benchmark for blade structural models, part A

    DEFF Research Database (Denmark)

    Lekou, D.J.; Chortis, D.; Belen Fariñas, A.

    2013-01-01

    Task 2.2 of the InnWind.Eu project. The benchmark is based on the reference wind turbine and the reference blade provided by DTU [1]. "Structural Concept developers/modelers" of WP2 were provided with the necessary input for a comparison numerical simulation run, upon definition of the reference blade......A benchmark on structural design methods for blades was performed within the InnWind.Eu project under WP2 “Lightweight Rotor” Task 2.2 “Lightweight structural design”. The present document is describes the results of the comparison simulation runs that were performed by the partners involved within...

  2. Preliminary results of steel containment vessel model test

    International Nuclear Information System (INIS)

    Matsumoto, T.; Komine, K.; Arai, S.

    1997-01-01

    A high pressure test of a mixed-scaled model (1:10 in geometry and 1:4 in shell thickness) of a steel containment vessel (SCV), representing an improved boiling water reactor (BWR) Mark II containment, was conducted on December 11-12, 1996 at Sandia National Laboratories. This paper describes the preliminary results of the high pressure test. In addition, the preliminary post-test measurement data and the preliminary comparison of test data with pretest analysis predictions are also presented

  3. Impact Flash Physics: Modeling and Comparisons With Experimental Results

    Science.gov (United States)

    Rainey, E.; Stickle, A. M.; Ernst, C. M.; Schultz, P. H.; Mehta, N. L.; Brown, R. C.; Swaminathan, P. K.; Michaelis, C. H.; Erlandson, R. E.

    2015-12-01

    horizontal. High-speed radiometer measurements were made of the time-dependent impact flash at wavelengths of 350-1100 nm. We will present comparisons between these measurements and the output of APL's model. The results of this validation allow us to determine basic relationships between observed optical signatures and impact conditions.

  4. A retrospective case series evaluating Branemark BioHelix implants placed in a specialist private practice following 'conventional' procedures. One-year results after placement.

    Science.gov (United States)

    Thomsson, Mats; Esposito, Marco

    2008-01-01

    To evaluate, in a retrospective case series, survival rates and complications of Brånemark dental implants placed according to 'conventional' procedures in patients consecutively treated in a Swedish specialist private practice. Eighty-three consecutively treated patients received 89 final fixed prostheses (31 mandibular and 58 maxillary) supported by 310 (101 mandibular and 209 maxillary) implants placed according to 'conventional' procedures, that is, no implants shorter than 10mm, no immediate post-extractive implants and no bone grafting procedures. In 70 patients, implants were left to heal submerged, whereas 13 patients were treated according to a one-stage procedure. All restorations (40 screw-retained cross-arch bridges, 32 screw-retained partial bridges and 17 cemented single crowns) were delivered about 2 (mandible) to 3 or 4 (maxilla) months after implant placement. Outcome measures were prosthesis success, implant survival and complications. One year after implant placement, no patients had dropped-out. No prostheses or implants had failed and no biological or biomechanical complications had occurred. Brånemark BioHelix dental implants placed according to 'conventional' procedures in 'selected' patients provided excellent short-term results. Randomised clinical trials with suitable controls are needed to confirm these preliminary results.

  5. Cost-benefit analysis model: A tool for area-wide fruit fly management. Procedures manual

    International Nuclear Information System (INIS)

    Enkerlin, W.; Mumford, J.; Leach, A.

    2007-03-01

    The Generic Fruit Fly Cost-Benefit Analysis Model assists in economic decision making associated with area-wide fruit fly control options. The FRUIT FLY COST-BENEFIT ANALYSIS PROGRAM (available on 1 CD-ROM from the Joint FAO/IAEA Programme of Nuclear Techniques in Food and Agriculture) is an Excel 2000 Windows based program, for which all standard Windows and Excel conventions apply. The Model is user friendly and thus largely self-explanatory. Nevertheless, it includes a procedures manual that has been prepared to guide the user, and thus should be used together with the software. Please note that the table presenting the pest management options in the Introductory Page of the model is controlled by spin buttons and click boxes. These controls are linked to macros that hide non relevant tables and boxes. N.B. it is important that the medium level of security is selected from the Tools menu of Excel, to do this go to Tools|Macros|Security| and select Medium. When the file is opened a form will appear containing three buttons, click on the middle button, 'Enable Macros', so that the macros may be used. Ideally the model should be used as a support tool by working groups aiming at assessing the economic returns of different fruit fly control options (suppression, eradication, containment and prevention). The working group should include professionals in agriculture with experience in area-wide implementation of integrated pest management programmes, an economist or at least someone with basic knowledge in economics, and if relevant, an entomologist with some background in the application of the sterile insect technique (SIT)

  6. Emotion regulation strategies: procedure modeling of J. Gross and cultural activity approach

    Directory of Open Access Journals (Sweden)

    Elena I. Pervichko

    2015-03-01

    Full Text Available The first part of this paper argued the desirability of structural-dynamic model of emotion regulation in the theoretical and methodological framework of cultural activity paradigm with the construction of a psychologically-based typology of emotion regulation strategies in norm and pathology, and also psychological mechanisms enabling the regulation of emotions. This conclusion was based on the analysis of the basic concepts and paradigms in which the issue of emotion regulation is studied: cognitive and psychoanalytic approaches, concept and emotional development of emotional intelligence, cultural activity approach. The paper considers the procedure model of emotion regulation by J. Gross, identifies emotion regulation strategies and evaluates their effectiveness. The possibilities and limitations of the model. Based on the review of the today research the conclusion is arrived at that the existing labels on a wide range of regulatory strategies remain an open issue.The author’s definition of emotion regulation is drawn. Emotion regulation is deemed as a set of mental processes, psychological mechanisms and regulatory strategies that people use to preserve the capacity for productive activities in a situation of emotional stress; to ensure optimal impulse control and emotions; to maintain the excitement at the optimum level. The second part of this paper provides the general description of emotion regulation strategies, the approach to their typology, the psychological mechanisms of emotion regulation that lie in the basis of this typology, i.e. the main elements of the structural-dynamic model of emotion regulation. The work shows theoretical and methodological efficacy of empirical significance of signs and symbols and also personal reflection. The diagnostic system to allow empirically identify a wide range of emotion regulation strategies is suggested. The psychological mechanisms used by the subject to solve the problem of emotional

  7. Homogenization procedures for the constitutive material modeling and analysis of aperiodic micro-structures

    Science.gov (United States)

    Aghalaya Manjunatha, Preetham

    Composite materials are the well-known substitutes for traditional metals in various industries because of their micro-structural character. Micro-structures provide a high strength-to-weight ratio, which makes them suitable for manufacturing large variety of applications ranging from simple toys to complicated space/aircraft structures. Since, these materials are widely used in high performance structures, their stress/thermal analysis issues are of major concern. Due to the high degree of material heterogeneity, it is extremely difficult to analyze such structures. Homogenization (rigorous averaging) is a process that overcomes the difficulty of modeling each micro-structure. It replaces an individual micro-structure by an equivalent material model representation (unit cell). Periodic micro-structures appear in regular intervals throughout the domain, in contrast aperiodic micro-structures follows an irregular pattern. Further, this method bridges the analysis gap between micro and macro domain of the structures. In this thesis, Homogenization procedure based on anti-periodic displacement fields for aperiodic micro-structures and aperiodic boundary conditions are considered to model the constitutive material matrix. This work could be easily implemented with the traditional finite element packages. In addition, it eventually increases the convergence accuracy and reduces the high computational expenses. Different problems are analyzed by the implementation of digital image processing schemes for the extraction of a unit cell around the Gauss quadrature points and the mesh-generation. In the future, this research defines a new path for the analysis of any random heterogeneous materials by its ease of implementation and the state-of-the-art micro-structure material modeling capabilities and digital image based micro-meshing.

  8. Mechanical test results on Dipole model C-1 25 mm aluminum collars

    International Nuclear Information System (INIS)

    Peters, C.

    1985-02-01

    This report is a summary of procedures used in collaring the SSC Dipole model C-1. Included are descriptions of the collars, instrumentation, collar pack preparation, collaring procedures, and collar dimension and coil pressure data measurements taken during and testing of the magnet

  9. Generic Procedure for Coupling the PHREEQC Geochemical Modeling Framework with Flow and Solute Transport Simulators

    Science.gov (United States)

    Wissmeier, L. C.; Barry, D. A.

    2009-12-01

    Computer simulations of water availability and quality play an important role in state-of-the-art water resources management. However, many of the most utilized software programs focus either on physical flow and transport phenomena (e.g., MODFLOW, MT3DMS, FEFLOW, HYDRUS) or on geochemical reactions (e.g., MINTEQ, PHREEQC, CHESS, ORCHESTRA). In recent years, several couplings between both genres of programs evolved in order to consider interactions between flow and biogeochemical reactivity (e.g., HP1, PHWAT). Software coupling procedures can be categorized as ‘close couplings’, where programs pass information via the memory stack at runtime, and ‘remote couplings’, where the information is exchanged at each time step via input/output files. The former generally involves modifications of software codes and therefore expert programming skills are required. We present a generic recipe for remotely coupling the PHREEQC geochemical modeling framework and flow and solute transport (FST) simulators. The iterative scheme relies on operator splitting with continuous re-initialization of PHREEQC and the FST of choice at each time step. Since PHREEQC calculates the geochemistry of aqueous solutions in contact with soil minerals, the procedure is primarily designed for couplings to FST’s for liquid phase flow in natural environments. It requires the accessibility of initial conditions and numerical parameters such as time and space discretization in the input text file for the FST and control of the FST via commands to the operating system (batch on Windows; bash/shell on Unix/Linux). The coupling procedure is based on PHREEQC’s capability to save the state of a simulation with all solid, liquid and gaseous species as a PHREEQC input file by making use of the dump file option in the TRANSPORT keyword. The output from one reaction calculation step is therefore reused as input for the following reaction step where changes in element amounts due to advection

  10. Computer Simulation Model to Train Medical Personnel on Glucose Clamp Procedures.

    Science.gov (United States)

    Maghoul, Pooya; Boulet, Benoit; Tardif, Annie; Haidar, Ahmad

    2017-10-01

    A glucose clamp procedure is the most reliable way to quantify insulin pharmacokinetics and pharmacodynamics, but skilled and trained research personnel are required to frequently adjust the glucose infusion rate. A computer environment that simulates glucose clamp experiments can be used for efficient personnel training and development and testing of algorithms for automated glucose clamps. We built 17 virtual healthy subjects (mean age, 25±6 years; mean body mass index, 22.2±3 kg/m 2 ), each comprising a mathematical model of glucose regulation and a unique set of parameters. Each virtual subject simulates plasma glucose and insulin concentrations in response to intravenous insulin and glucose infusions. Each virtual subject provides a unique response, and its parameters were estimated from combined intravenous glucose tolerance test-hyperinsulinemic-euglycemic clamp data using the Bayesian approach. The virtual subjects were validated by comparing their simulated predictions against data from 12 healthy individuals who underwent a hyperglycemic glucose clamp procedure. Plasma glucose and insulin concentrations were predicted by the virtual subjects in response to glucose infusions determined by a trained research staff performing a simulated hyperglycemic clamp experiment. The total amount of glucose infusion was indifferent between the simulated and the real subjects (85±18 g vs. 83±23 g; p=NS) as well as plasma insulin levels (63±20 mU/L vs. 58±16 mU/L; p=NS). The virtual subjects can reliably predict glucose needs and plasma insulin profiles during hyperglycemic glucose clamp conditions. These virtual subjects can be used to train personnel to make glucose infusion adjustments during clamp experiments. Copyright © 2017 Diabetes Canada. Published by Elsevier Inc. All rights reserved.

  11. Comparison of procedures for immediate reconstruction of large osseous defects resulting from removal of a single tooth to prepare for insertion of an endosseous implant after healing

    NARCIS (Netherlands)

    Raghoebar, G. M.; Slater, J. J. H.; den Hartog, L.; Meijer, H. J. A.; Vissink, A.

    This study evaluated the treatment outcome of immediate reconstruction of 45 large osseous defects resulting from removal of a single tooth with a 1:2 mixture of Bio-Oss(R) and autologous tuberosity bone, and three different procedures for soft tissue closing (Bio-Gide(R) membrane, connective tissue

  12. Position-sensitive transition edge sensor modeling and results

    Energy Technology Data Exchange (ETDEWEB)

    Hammock, Christina E-mail: chammock@milkyway.gsfc.nasa.gov; Figueroa-Feliciano, Enectali; Apodaca, Emmanuel; Bandler, Simon; Boyce, Kevin; Chervenak, Jay; Finkbeiner, Fred; Kelley, Richard; Lindeman, Mark; Porter, Scott; Saab, Tarek; Stahle, Caroline

    2004-03-11

    We report the latest design and experimental results for a Position-Sensitive Transition-Edge Sensor (PoST). The PoST is motivated by the desire to achieve a larger field-of-view without increasing the number of readout channels. A PoST consists of a one-dimensional array of X-ray absorbers connected on each end to a Transition Edge Sensor (TES). Position differentiation is achieved through a comparison of pulses between the two TESs and X-ray energy is inferred from a sum of the two signals. Optimizing such a device involves studying the available parameter space which includes device properties such as heat capacity and thermal conductivity as well as TES read-out circuitry parameters. We present results for different regimes of operation and the effects on energy resolution, throughput, and position differentiation. Results and implications from a non-linear model developed to study the saturation effects unique to PoSTs are also presented.

  13. Guided bone regeneration: dynamic procedures versus static shielding in an animal model.

    Science.gov (United States)

    Lethaus, Bernd; Tudor, Christian; Bumiller, Lars; Birkholz, Torsten; Wiltfang, Jörg; Kessler, Peter

    2010-10-01

    Due to its osteoinductive potential, the periosteum plays a crucial role in the process of neoosteogenesis. Therefore, periosteal elevation can lead to new bone formation in an artificially created space. In this study, we compared dynamic periosteal elevation with static shielding in an animal experiment. Different elevation/shielding heights of 5, 10, and 15 mm were tested with regard to various consolidation periods. Histological analysis, histomorphometry, and microradiography were used to measure the quantity and quality of the newly formed bone. No significant differences regarding bone quantity or quality were found between the two techniques. The cumulative results for the bone regeneration in the space created by distraction/elevation were about 66% in the dynamic and 67% in static procedure. The main advantages of both techniques are minimal invasion and low morbidity. In terms of clinical applications, periosteal elevation could be applied in cranio-maxillofacial surgery, in pre-implant augmentation and in reconstructive surgery.

  14. Comparison of blade-strike modeling results with empirical data

    Energy Technology Data Exchange (ETDEWEB)

    Ploskey, Gene R. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Carlson, Thomas J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2004-03-01

    This study is the initial stage of further investigation into the dynamics of injury to fish during passage through a turbine runner. As part of the study, Pacific Northwest National Laboratory (PNNL) estimated the probability of blade strike, and associated injury, as a function of fish length and turbine operating geometry at two adjacent turbines in Powerhouse 1 of Bonneville Dam. Units 5 and 6 had identical intakes, stay vanes, wicket gates, and draft tubes, but Unit 6 had a new runner and curved discharge ring to minimize gaps between the runner hub and blades and between the blade tips and discharge ring. We used a mathematical model to predict blade strike associated with two Kaplan turbines and compared results with empirical data from biological tests conducted in 1999 and 2000. Blade-strike models take into consideration the geometry of the turbine blades and discharges as well as fish length, orientation, and distribution along the runner. The first phase of this study included a sensitivity analysis to consider the effects of difference in geometry and operations between families of turbines on the strike probability response surface. The analysis revealed that the orientation of fish relative to the leading edge of a runner blade and the location that fish pass along the blade between the hub and blade tip are critical uncertainties in blade-strike models. Over a range of discharges, the average prediction of injury from blade strike was two to five times higher than average empirical estimates of visible injury from shear and mechanical devices. Empirical estimates of mortality may be better metrics for comparison to predicted injury rates than other injury measures for fish passing at mid-blade and blade-tip locations.

  15. Implementation and evaluation of nonparametric regression procedures for sensitivity analysis of computationally demanding models

    International Nuclear Information System (INIS)

    Storlie, Curtis B.; Swiler, Laura P.; Helton, Jon C.; Sallaberry, Cedric J.

    2009-01-01

    The analysis of many physical and engineering problems involves running complex computational models (simulation models, computer codes). With problems of this type, it is important to understand the relationships between the input variables (whose values are often imprecisely known) and the output. The goal of sensitivity analysis (SA) is to study this relationship and identify the most significant factors or variables affecting the results of the model. In this presentation, an improvement on existing methods for SA of complex computer models is described for use when the model is too computationally expensive for a standard Monte-Carlo analysis. In these situations, a meta-model or surrogate model can be used to estimate the necessary sensitivity index for each input. A sensitivity index is a measure of the variance in the response that is due to the uncertainty in an input. Most existing approaches to this problem either do not work well with a large number of input variables and/or they ignore the error involved in estimating a sensitivity index. Here, a new approach to sensitivity index estimation using meta-models and bootstrap confidence intervals is described that provides solutions to these drawbacks. Further, an efficient yet effective approach to incorporate this methodology into an actual SA is presented. Several simulated and real examples illustrate the utility of this approach. This framework can be extended to uncertainty analysis as well.

  16. Results of EPRI/ANL DCH investigations and model development

    International Nuclear Information System (INIS)

    Spencer, B.W.; Sienicki, J.J.; Sehgal, B.R.; Merilo, M.

    1988-01-01

    The results of a series of five experiments are described addressing the severity and mitigation of direct containment heating. The tests were performed in a 1:30 linear scale mockup of the Zion PWR containment system using a reactor-material corium melt consisting of 60% UO 2 , 16% ZrO 2 , 24% SSt at nominally 2800C initial temperature. A ''worst-case'' type test involving unimpeded corium dispersal through an air atmosphere in a closed vessel produced an atmosphere heatup of 323K, equivalent to a DCH efficiency of 62%. With the addition of structural features which impeded the corium dispersal, representative of dispersal pathway features at Zion, the DCH efficiency was reduced to 1--5%. (This important result is scale dependent and requires larger scale tests such as the SURTSEY program at SNL plus mechanistic modeling for application to the reactor system.) With the addition of water in the cavity region, there was no measurable heatup of the atmosphere. This was attributable to the vigorous codispersal of water with corium which prevented the temperature of the atmosphere from significantly exceeding T/sub sat/. In this case the DCH load was replaced by the more benign ''steam spike'' from corium quench. Significant oxidation of the corium constituents occurred in the tests, adding chemical energy to the system and producing hydrogen. Overall, the results suggest that with consideration of realistic, plant specific, mitigating features, DCH may be no worse and possibly far less severe than the previously examined steam spike. Implications for accident management are addressed. 17 refs., 7 figs., 4 tabs

  17. Station-based deconstructed training model for teaching procedural skills to medical students: a quasi-experimental study

    Directory of Open Access Journals (Sweden)

    Mahdi Panah Khahi

    2010-09-01

    Full Text Available Seyyed M Razavi1, Mojgan Karbakhsh1, Mahdi Panah Khahi2, Soheila Dabiran1, Sara Asefi3, GhamarH Zaker Shahrak4, Ali R Bad Afrooz41Department of Community Medicine, 2Department of Anesthesiology, 3Department of General Practice, 4Clinical Skills Center, Tehran University of Medical Sciences, IranBackground: Every procedural skill consists of some microskills. One of the effective techniques for teaching a main procedural skill is to deconstruct the skill into a series of microskills and train students on each microskill separately. When we learn microskills, we will learn the main skill also. This model can be beneficial for tuition on procedural skills.Objective: In this study, we propose a stationed-based deconstructed training model for tuition of each microskill, and then we assessed the medical students’ self-perceived abilities.Methods: This quasi-experimental study was conducted in 268 medical students (536 matched pre- and post-questionnaires at the surgical clerkship stage during five consecutive years in three teaching and learning groups. In this study, we taught each skill in 10 steps (proposed model to the students. We then evaluated the students’ self-perceived abilities using a pre- and post-self-assessment technique. SPSS v13 software with one-way analysis of variance and paired t-tests were used for data collection and analysis.Results: Assessment of medical students’ perceived abilities before and after training showed a significant improvement (P < 0.001 in both cognitive and practical domains. There were also significant differences between the three teaching and learning groups (P < 0.001. There were no significant differences for the different years of training regarding the observed improvement.Conclusion: This study suggests that deconstructing the practical skills into microskills and tuition of those microskills via the separated structured educational stations is effective according to the students’ self

  18. A Duality Result for the Generalized Erlang Risk Model

    Directory of Open Access Journals (Sweden)

    Lanpeng Ji

    2014-11-01

    Full Text Available In this article, we consider the generalized Erlang risk model and its dual model. By using a conditional measure-preserving correspondence between the two models, we derive an identity for two interesting conditional probabilities. Applications to the discounted joint density of the surplus prior to ruin and the deficit at ruin are also discussed.

  19. An inverse modeling procedure to determine particle growth and nucleation rates from measured aerosol size distributions

    Directory of Open Access Journals (Sweden)

    B. Verheggen

    2006-01-01

    Full Text Available Classical nucleation theory is unable to explain the ubiquity of nucleation events observed in the atmosphere. This shows a need for an empirical determination of the nucleation rate. Here we present a novel inverse modeling procedure to determine particle nucleation and growth rates based on consecutive measurements of the aerosol size distribution. The particle growth rate is determined by regression analysis of the measured change in the aerosol size distribution over time, taking into account the effects of processes such as coagulation, deposition and/or dilution. This allows the growth rate to be determined with a higher time-resolution than can be deduced from inspecting contour plots ('banana-plots''. Knowing the growth rate as a function of time enables the evaluation of the time of nucleation of measured particles of a certain size. The nucleation rate is then obtained by integrating the particle losses from time of measurement to time of nucleation. The regression analysis can also be used to determine or verify the optimum value of other parameters of interest, such as the wall loss or coagulation rate constants. As an example, the method is applied to smog chamber measurements. This program offers a powerful interpretive tool to study empirical aerosol population dynamics in general, and nucleation and growth in particular.

  20. The Relationship between the Bock-Aitkin Procedure and the EM Algorithm for IRT Model Estimation.

    Science.gov (United States)

    Hsu, Yaowen; Ackerman, Terry A.; Fan, Meichu

    It has previously been shown that the Bock-Aitkin procedure (R. Bock and M. Aitkin, 1981) is an instance of the EM algorithm when trying to find the marginal maximum likelihood estimate for a discrete latent ability variable (latent trait). In this paper, it is shown that the Bock-Aitkin procedure is a numerical implementation of the EM algorithm…

  1. Establishing the ferret as a gyrencephalic animal model of traumatic brain injury: Optimization of controlled cortical impact procedures.

    Science.gov (United States)

    Schwerin, Susan C; Hutchinson, Elizabeth B; Radomski, Kryslaine L; Ngalula, Kapinga P; Pierpaoli, Carlo M; Juliano, Sharon L

    2017-06-15

    Although rodent TBI studies provide valuable information regarding the effects of injury and recovery, an animal model with neuroanatomical characteristics closer to humans may provide a more meaningful basis for clinical translation. The ferret has a high white/gray matter ratio, gyrencephalic neocortex, and ventral hippocampal location. Furthermore, ferrets are amenable to behavioral training, have a body size compatible with pre-clinical MRI, and are cost-effective. We optimized the surgical procedure for controlled cortical impact (CCI) using 9 adult male ferrets. We used subject-specific brain/skull morphometric data from anatomical MRIs to overcome across-subject variability for lesion placement. We also reflected the temporalis muscle, closed the craniotomy, and used antibiotics. We then gathered MRI, behavioral, and immunohistochemical data from 6 additional animals using the optimized surgical protocol: 1 control, 3 mild, and 1 severely injured animals (surviving one week) and 1 moderately injured animal surviving sixteen weeks. The optimized surgical protocol resulted in consistent injury placement. Astrocytic reactivity increased with injury severity showing progressively greater numbers of astrocytes within the white matter. The density and morphological changes of microglia amplified with injury severity or time after injury. Motor and cognitive impairments scaled with injury severity. The optimized surgical methods differ from those used in the rodent, and are integral to success using a ferret model. We optimized ferret CCI surgery for consistent injury placement. The ferret is an excellent animal model to investigate pathophysiological and behavioral changes associated with TBI. Published by Elsevier B.V.

  2. Waste glass corrosion modeling: Comparison with experimental results

    International Nuclear Information System (INIS)

    Bourcier, W.L.

    1994-01-01

    Models for borosilicate glass dissolution must account for the processes of (1) kinetically-controlled network dissolution, (2) precipitation of secondary phases, (3) ion exchange, (4) rate-limiting diffusive transport of silica through a hydrous surface reaction layer, and (5) specific glass surface interactions with dissolved cations and anions. Current long-term corrosion models for borosilicate glass employ a rate equation consistent with transition state theory embodied in a geochemical reaction-path modeling program that calculates aqueous phase speciation and mineral precipitation/dissolution. These models are currently under development. Future experimental and modeling work to better quantify the rate-controlling processes and validate these models are necessary before the models can be used in repository performance assessment calculations

  3. Argonne Fuel Cycle Facility ventilation system -- modeling and results

    International Nuclear Information System (INIS)

    Mohr, D.; Feldman, E.E.; Danielson, W.F.

    1995-01-01

    This paper describes an integrated study of the Argonne-West Fuel Cycle Facility (FCF) interconnected ventilation systems during various operations. Analyses and test results include first a nominal condition reflecting balanced pressures and flows followed by several infrequent and off-normal scenarios. This effort is the first study of the FCF ventilation systems as an integrated network wherein the hydraulic effects of all major air systems have been analyzed and tested. The FCF building consists of many interconnected regions in which nuclear fuel is handled, transported and reprocessed. The ventilation systems comprise a large number of ducts, fans, dampers, and filters which together must provide clean, properly conditioned air to the worker occupied spaces of the facility while preventing the spread of airborne radioactive materials to clean am-as or the atmosphere. This objective is achieved by keeping the FCF building at a partial vacuum in which the contaminated areas are kept at lower pressures than the other worker occupied spaces. The ventilation systems of FCF and the EBR-II reactor are analyzed as an integrated totality, as demonstrated. We then developed the network model shown in Fig. 2 for the TORAC code. The scope of this study was to assess the measured results from the acceptance/flow balancing testing and to predict the effects of power failures, hatch and door openings, single-failure faulted conditions, EBR-II isolation, and other infrequent operations. The studies show that the FCF ventilation systems am very controllable and remain stable following off-normal events. In addition, the FCF ventilation system complex is essentially immune to reverse flows and spread of contamination to clean areas during normal and off-normal operation

  4. ExEP yield modeling tool and validation test results

    Science.gov (United States)

    Morgan, Rhonda; Turmon, Michael; Delacroix, Christian; Savransky, Dmitry; Garrett, Daniel; Lowrance, Patrick; Liu, Xiang Cate; Nunez, Paul

    2017-09-01

    EXOSIMS is an open-source simulation tool for parametric modeling of the detection yield and characterization of exoplanets. EXOSIMS has been adopted by the Exoplanet Exploration Programs Standards Definition and Evaluation Team (ExSDET) as a common mechanism for comparison of exoplanet mission concept studies. To ensure trustworthiness of the tool, we developed a validation test plan that leverages the Python-language unit-test framework, utilizes integration tests for selected module interactions, and performs end-to-end crossvalidation with other yield tools. This paper presents the test methods and results, with the physics-based tests such as photometry and integration time calculation treated in detail and the functional tests treated summarily. The test case utilized a 4m unobscured telescope with an idealized coronagraph and an exoplanet population from the IPAC radial velocity (RV) exoplanet catalog. The known RV planets were set at quadrature to allow deterministic validation of the calculation of physical parameters, such as working angle, photon counts and integration time. The observing keepout region was tested by generating plots and movies of the targets and the keepout zone over a year. Although the keepout integration test required the interpretation of a user, the test revealed problems in the L2 halo orbit and the parameterization of keepout applied to some solar system bodies, which the development team was able to address. The validation testing of EXOSIMS was performed iteratively with the developers of EXOSIMS and resulted in a more robust, stable, and trustworthy tool that the exoplanet community can use to simulate exoplanet direct-detection missions from probe class, to WFIRST, up to large mission concepts such as HabEx and LUVOIR.

  5. Final model independent result of DAMA/LIBRA-phase1

    Energy Technology Data Exchange (ETDEWEB)

    Bernabei, R.; D' Angelo, S.; Di Marco, A. [Universita di Roma ' ' Tor Vergata' ' , Dipartimento di Fisica, Rome (Italy); INFN, sez. Roma ' ' Tor Vergata' ' , Rome (Italy); Belli, P. [INFN, sez. Roma ' ' Tor Vergata' ' , Rome (Italy); Cappella, F.; D' Angelo, A.; Prosperi, D. [Universita di Roma ' ' La Sapienza' ' , Dipartimento di Fisica, Rome (Italy); INFN, sez. Roma, Rome (Italy); Caracciolo, V.; Castellano, S.; Cerulli, R. [INFN, Laboratori Nazionali del Gran Sasso, Assergi (Italy); Dai, C.J.; He, H.L.; Kuang, H.H.; Ma, X.H.; Sheng, X.D.; Wang, R.G. [Chinese Academy, IHEP, Beijing (China); Incicchitti, A. [INFN, sez. Roma, Rome (Italy); Montecchia, F. [INFN, sez. Roma ' ' Tor Vergata' ' , Rome (Italy); Universita di Roma ' ' Tor Vergata' ' , Dipartimento di Ingegneria Civile e Ingegneria Informatica, Rome (Italy); Ye, Z.P. [Chinese Academy, IHEP, Beijing (China); University of Jing Gangshan, Jiangxi (China)

    2013-12-15

    The results obtained with the total exposure of 1.04 ton x yr collected by DAMA/LIBRA-phase1 deep underground at the Gran Sasso National Laboratory (LNGS) of the I.N.F.N. during 7 annual cycles (i.e. adding a further 0.17 ton x yr exposure) are presented. The DAMA/LIBRA-phase1 data give evidence for the presence of Dark Matter (DM) particles in the galactic halo, on the basis of the exploited model independent DM annual modulation signature by using highly radio-pure NaI(Tl) target, at 7.5{sigma} C.L. Including also the first generation DAMA/NaI experiment (cumulative exposure 1.33 ton x yr, corresponding to 14 annual cycles), the C.L. is 9.3{sigma} and the modulation amplitude of the single-hit events in the (2-6) keV energy interval is: (0.0112{+-}0.0012) cpd/kg/keV; the measured phase is (144{+-}7) days and the measured period is (0.998{+-}0.002) yr, values well in agreement with those expected for DM particles. No systematic or side reaction able to mimic the exploited DM signature has been found or suggested by anyone over more than a decade. (orig.)

  6. Innovation ecosystem model for commercialization of research results

    Directory of Open Access Journals (Sweden)

    Vlăduţ Gabriel

    2017-07-01

    Full Text Available Innovation means Creativity and Added value recognise by the market. The first step in creating a sustainable commercialization of research results, Technological Transfer – TT mechanism, on one hand is to define the “technology” which will be transferred and on other hand to define the context in which the TT mechanism work, the ecosystem. The focus must be set on technology as an entity, not as a science or a study of the practical industrial arts and certainly not any specific applied science. The transfer object, the technology, must rely on a subjectively determined but specifiable set of processes and products. Focusing on the product is not sufficient to the transfer and diffusion of technology. It is not merely the product that is transferred but also knowledge of its use and application. The innovation ecosystem model brings together new companies, experienced business leaders, researchers, government officials, established technology companies, and investors. This environment provides those new companies with a wealth of technical expertise, business experience, and access to capital that supports innovation in the early stages of growth.

  7. Blade element momentum modeling of inflow with shear in comparison with advanced model results

    DEFF Research Database (Denmark)

    Aagaard Madsen, Helge; Riziotis, V.; Zahle, Frederik

    2012-01-01

    shear is present in the inflow. This gives guidance to how the BEM modeling of shear should be implemented. Another result from the advanced vortex model computations is a clear indication of influence of the ground, and the general tendency is a speed up effect of the flow through the rotor giving...

  8. Regionalization of climate model results for the North Sea

    Energy Technology Data Exchange (ETDEWEB)

    Kauker, F.

    1999-07-01

    A dynamical downscaling is presented that allows an estimation of potential effects of climate change on the North Sea. Therefore, the ocean general circulation model OPYC is adapted for application on a shelf by adding a lateral boundary formulation and a tide model. In this set-up the model is forced, first, with data from the ECMWF reanalysis for model validation and the study of the natural variability, and, second, with data from climate change experiments to estimate the effects of climate change on the North Sea. (orig.)

  9. Field Test Evaluation of Conservation Retrofits of Low-Income, Single-Family Buildings in Wisconsin: Blower-Door-Directed Infiltration Reduction Procedure, Field Test Implementation and Results

    Energy Technology Data Exchange (ETDEWEB)

    Gettings, M.B.

    2001-05-21

    A blower-door-directed infiltration retrofit procedure was field tested on 18 homes in south central Wisconsin. The procedure, developed by the Wisconsin Energy Conservation Corporation, includes recommended retrofit techniques as well as criteria for estimating the amount of cost-effective work to be performed on a house. A recommended expenditure level and target air leakage reduction, in air changes per hour at 50 Pascal (ACH50), are determined from the initial leakage rate measured. The procedure produced an average 16% reduction in air leakage rate. For the 7 houses recommended for retrofit, 89% of the targeted reductions were accomplished with 76% of the recommended expenditures. The average cost of retrofits per house was reduced by a factor of four compared with previous programs. The average payback period for recommended retrofits was 4.4 years, based on predicted energy savings computed from achieved air leakage reductions. Although exceptions occurred, the procedure's 8 ACH50 minimum initial leakage rate for advising retrofits to be performed appeared a good choice, based on cost-effective air leakage reduction. Houses with initial rates of 7 ACH50 or below consistently required substantially higher costs to achieve significant air leakage reductions. No statistically significant average annual energy savings was detected as a result of the infiltration retrofits. Average measured savings were -27 therm per year, indicating an increase in energy use, with a 90% confidence interval of 36 therm. Measured savings for individual houses varied widely in both positive and negative directions, indicating that factors not considered affected the results. Large individual confidence intervals indicate a need to increase the accuracy of such measurements as well as understand the factors which may cause such disparity. Recommendations for the procedure include more extensive training of retrofit crews, checks for minimum air exchange rates to insure air

  10. Sexual and functional results after creation of a neovagina in women with Mayer-Rokitansky-Küster-Hauser syndrome: a comparison of nonsurgical and surgical procedures.

    Science.gov (United States)

    Morcel, Karine; Lavoué, Vincent; Jaffre, Frédérique; Paniel, Bernard-Jean; Rouzier, Roman

    2013-07-01

    To compare nonsurgical and surgical procedures for creation of a neovagina in women with Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome in terms of sexual satisfaction. We report a cross-sectional study of 91 women with MRKH syndrome undergoing a neovagina creation procedure. They were members of the French National Association of Women with MRKH syndrome. We analyzed all answers to a questionnaire mailed to each woman. The questionnaire solicited short answers concerning the diagnosis and the neovagina procedure, and included the standardized FSFI (Female Sexual Function Index) questionnaire. All analyses were performed using the chi-squared test and Student's t-test. A p-value of technique (8 cases) (surgical group). The mean time after neovagina creation was 7 years (range 1-44 years). The population characteristics did not differ significantly between the nonsurgical and surgical groups. The total FSFI score indicated good and similar functional results in the two groups (25.3±7.5 versus 25.3±8.0). Functional sexual outcomes after nonsurgical and surgical methods were similar. Therefore, the Frank's method should be proposed as first line therapy because it is less invasive than surgical procedures. In the case of failure of this technique or of refusal by the patient, surgical reconstruction may then be offered. Copyright © 2013. Published by Elsevier Ireland Ltd.

  11. MODELING OF PROCESSES OF OVERCOMING CONTRADICTIONS OF THE STATE AND ECONOMIC OPERATORS FOR THE SECURITY AND FACILITATION OF CUSTOMS PROCEDURES

    Directory of Open Access Journals (Sweden)

    Berezhnyuk Ivan

    2018-03-01

    Full Text Available Introduction. The issue of simultaneous provision of economic security of the state and simplification of customs procedures is actualized nowadays. The author of the study stressed the importance to create a «safe» business environment from the point of view of the customs sphere, which is based on «security», «justice» and «stability». Purpose. Development of methodical recommendations for modeling the processes of overcoming contradictions of the state and subjects of foreign economic activity in the field of security and simplification of customs procedures. Results. The research indicates that the appointment of revenue and fee bodies is the creation of favorable conditions for the development of foreign economic activity, ensuring the safety of society, protecting the customs interests of Ukraine. When performing customs duties by the SFS, the tasks assigned to them, aimed at ensuring the correct application, strict observance and prevention of non-compliance with the requirements of the Ukrainian legislation on state customs issues, may present risks that are inherently contradictory, conflicting in terms of the vector of action with respect to each other, namely: the probability of non-compliance by the subjects of foreign trade with the norms of customs legislation, or the creation of significant bureaucratic barriers in the process of economic operators. There is a peculiar conflict of interests between the state and the subjects of foreign economic activity. The main direction of creating a favorable business environment in accordance with the recommendations of WCO is the process of further simplification of customs procedures for subjects with a high degree of trust, fighting corruption and facilitating the movement of goods, vehicles and people in general. Conclusions. Thus, the scheme of «relations» between the state and the subjects of foreign economic activity can be modeled by the means of game theory, which is

  12. Paediatric multidetector CT optimisation training: a survey of common scanning procedures and the resultant dose reduction associated with paediatric MDCT investigations in Australia

    International Nuclear Information System (INIS)

    Wallace, Anthony; Sibelle, Kimberly; Stanley, Martin; Budd, Ray; Goergen, Stacey; Heggie, John

    2008-01-01

    The growing recognition of the increased risk of stochastic injury to paediatric patients from multidetector CT (MDCT) investigations prompted a survey sponsored by Royal Australian and New Zealand College of Radiology (RANZCR), Austin Health and Monash University to initiate a national paediatric dosimetry review for some of the most common investigations undertaken in MDCT paediatric practice. The survey forms included a data sheet requiring acquisition protocol parameters and a phantom graphic sheet requiring the marking of the inferior and superior acquisition margins. Survey forms were supplied for each of 13 common MDCT acquisitions to be tested. Response data was input into CT-Expo Version 1.5.1., a CT dosimetry calculation engine, to determine dose length product (DLP (mGy.cm)) and effective dose (ED (mSv)). Initial survey data was collected, calculated, blinded and collated into various presentations that were given at a MDCT optimisation seminar in November, 2006. All sites were re-surveyed in May 2007 and doses calculated. Initial survey data showed a range of dose efficiencies spread across the surveyed sites. A measure of the initial spread of DLP values per procedure ranged from a minimum of less than 2 for a head-trauma acquisition (372 - 520 mGy.cm) to 14 for a chest-trauma acquisition (28 - 388 mGy.cm). Results of the 2nd survey strongly indicate that the application of optimisation training to paediatric MDCT scanning can produce significant dose savings by the application of simple dose saving strategies. Many protocols demonstrated dose reductions of greater than 50% with significant reductions in both the maximum and minimum values of calculated DLP and ED. The development of a survey-training-resurvey model of MDCT optimisation has proven to be a successful strategy for paediatric MDCT dose reduction in Australia. (author)

  13. Procedural justice, legitimacy beliefs, and moral disengagement in emerging adulthood: Explaining continuity and desistance in the moral model of criminal lifestyle development.

    Science.gov (United States)

    Walters, Glenn D

    2018-02-01

    Research has shown that procedural justice reliably predicts future offending behavior, although there is some indication that this may be more a function of legitimacy beliefs than of procedural justice per se. The current study sought to explain continuity and desistance in the moral model of criminal lifestyle development by comparing legitimacy beliefs, procedural justice, and moral disengagement as initiators and mediators of pathways leading to early adult offending. It was hypothesized that low legitimacy beliefs but not perceived procedural (in)justice or moral disengagement would initiate, and that moral disengagement but not low legitimacy beliefs or procedural injustice would mediate, the effect of low legitimacy beliefs on subsequent offending behavior. This hypothesis was tested in a group of 1,142 young adult males (age range = 18 to 20) from the Pathways to Desistance study (Mulvey, 2012). Results showed that as predicted, the target pathway (legitimacy → moral disengagement → offending) but none of the control pathways achieved a significant indirect effect. Hence, 1 way legitimacy beliefs reduce future offending and lead to desistance is by inhibiting moral disengagement. Besides the theoretical implications of these results, there is also the suggestion that legitimacy beliefs and moral disengagement should be considered for inclusion in secondary prevention and criminal justice intervention programs. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  14. Effect of geometry of rice kernels on drying modeling results

    Science.gov (United States)

    Geometry of rice grain is commonly represented by sphere, spheroid or ellipsoid shapes in the drying models. Models using simpler shapes are easy to solve mathematically, however, deviation from the true grain shape might lead to large errors in predictions of drying characteristics such as, moistur...

  15. Spinal cord stimulation: modeling results and clinical data

    NARCIS (Netherlands)

    Struijk, Johannes J.; Struijk, J.J.; Holsheimer, J.; Barolat, Giancarlo; He, Jiping

    1992-01-01

    The potential distribution in volume couductor models of the spinal cord at cervical, midthoracic and lowthoracic levels, due to epidural stimulation, was calculated. Treshold stimuli of modeled myelhated dorsal column and dorsal root fibers were calculated and were compared with perception

  16. Quark cluster model of nuclei and lepton scattering results

    International Nuclear Information System (INIS)

    Vary, J.P.; Iowa State Univ. of Science and Technology, Ames

    1984-01-01

    A review of the quark cluster model (QCM) of nuclei is presented along with applications to deep inelastic lepton scattering and elastic lepton scattering experiments. In addition a sample comparison is made with high momentum transfer (p, π) data. The QCM prediction for the ratio of nuclear structure functions in the x > 1 domain is discussed as a critical test of the model

  17. How to: understanding SWAT model uncertainty relative to measured results

    Science.gov (United States)

    Watershed models are being relied upon to contribute to most policy-making decisions of watershed management, and the demand for an accurate accounting of complete model uncertainty is rising. Generalized likelihood uncertainty estimation (GLUE) is a widely used method for quantifying uncertainty i...

  18. Toxicological Evaluation/Verification of Decontamination Procedures/Products from Alternative Technologies for Chemical Demilitarization: Department of Transportation (DOT) Test Results for a Mustard (HD) Wastestream

    National Research Council Canada - National Science Library

    Manthei, James

    1998-01-01

    ...) required procedures in rats (orally) and rabbits (dermally) . The reacted HD water by-products produced no deaths in either species, and there were no observable toxic effects and no dermal irritation in rabbits. Therefore, for purposes of the DoT regulations, this material is a Category III material for packaging purposes, but these final results must also be confirmed by the inhalation route in rats.

  19. results

    Directory of Open Access Journals (Sweden)

    Salabura Piotr

    2017-01-01

    Full Text Available HADES experiment at GSI is the only high precision experiment probing nuclear matter in the beam energy range of a few AGeV. Pion, proton and ion beams are used to study rare dielectron and strangeness probes to diagnose properties of strongly interacting matter in this energy regime. Selected results from p + A and A + A collisions are presented and discussed.

  20. [Analytical procedure of variable number of tandem repeats (VNTR) analysis and effective use of analysis results for tuberculosis control].

    Science.gov (United States)

    Hachisu, Yushi; Hashimoto, Ruiko; Kishida, Kazunori; Yokoyama, Eiji

    2013-12-01

    Variable number of tandem repeats (VNTR) analysis is one of the methods for molecular epidemiological studies of Mycobacterium tuberculosis. VNTR analysis is a method based on PCR, provides rapid highly reproducible results and higher strain discrimination power than the restriction fragment length polymorphism (RFLP) analysis widely used in molecular epidemiological studies of Mycobacterium tuberculosis. Genetic lineage compositions of Mycobacterium tuberculosis clinical isolates differ among the regions from where they are isolated, and allelic diversity at each locus also differs among the genetic lineages of Mycobacterium tuberculosis. Therefore, the combination of VNTR loci that can provide high discrimination capacity for analysis is not common in every region. The Japan Anti-Tuberculosis Association (JATA) 12 (15) reported a standard combination of VNTR loci for analysis in Japan, and the combination with hypervariable (HV) loci added to JATA12 (15), which has very high discrimination capacity, was also reported. From these reports, it is thought that data sharing between institutions and construction of a nationwide database will progress from now on. Using database construction of VNTR profiles, VNTR analysis has become an effective tool to trace the route of tuberculosis infection, and also helps in decision-making in the treatment course. However, in order to utilize the results of VNTR analysis effectively, it is important that each related organization cooperates closely, and analysis should be appropriately applied in the system in which accurate control and private information protection are ensured.

  1. Wave-current interactions: model development and preliminary results

    Science.gov (United States)

    Mayet, Clement; Lyard, Florent; Ardhuin, Fabrice

    2013-04-01

    The coastal area concentrates many uses that require integrated management based on diagnostic and predictive tools to understand and anticipate the future of pollution from land or sea, and learn more about natural hazards at sea or activity on the coast. The realistic modelling of coastal hydrodynamics needs to take into account various processes which interact, including tides, surges, and sea state (Wolf [2008]). These processes act at different spatial scales. Unstructured-grid models have shown the ability to satisfy these needs, given that a good mesh resolution criterion is used. We worked on adding a sea state forcing in a hydrodynamic circulation model. The sea state model is the unstructured version of WAVEWATCH III c (Tolman [2008]) (which version is developed at IFREMER, Brest (Ardhuin et al. [2010]) ), and the hydrodynamic model is the 2D barotropic module of the unstructured-grid finite element model T-UGOm (Le Bars et al. [2010]). We chose to use the radiation stress approach (Longuet-Higgins and Stewart [1964]) to represent the effect of surface waves (wind waves and swell) in the barotropic model, as previously done by Mastenbroek et al. [1993]and others. We present here some validation of the model against academic cases : a 2D plane beach (Haas and Warner [2009]) and a simple bathymetric step with analytic solution for waves (Ardhuin et al. [2008]). In a second part we present realistic application in the Ushant Sea during extreme event. References Ardhuin, F., N. Rascle, and K. Belibassakis, Explicit wave-averaged primitive equations using a generalized Lagrangian mean, Ocean Modelling, 20 (1), 35-60, doi:10.1016/j.ocemod.2007.07.001, 2008. Ardhuin, F., et al., Semiempirical Dissipation Source Functions for Ocean Waves. Part I: Definition, Calibration, and Validation, J. Phys. Oceanogr., 40 (9), 1917-1941, doi:10.1175/2010JPO4324.1, 2010. Haas, K. A., and J. C. Warner, Comparing a quasi-3D to a full 3D nearshore circulation model: SHORECIRC and

  2. Applying A Multi-Objective Based Procedure to SWAT Modelling in Alpine Catchments

    Science.gov (United States)

    Tuo, Y.; Disse, M.; Chiogna, G.

    2017-12-01

    In alpine catchments, water management practices can lead to conflicts between upstream and downstream stakeholders, like in the Adige river basin (Italy). A correct prediction of available water resources plays an important part, for example, in defining how much water can be stored for hydropower production in upstream reservoirs without affecting agricultural activities downstream. Snow is a crucial hydrological component that highly affects seasonal behavior of streamflow. Therefore, a realistic representation of snow dynamics is fundamental for water management operations in alpine catchments. The Soil and Water Assessment Tool (SWAT) model has been applied in alpine catchments worldwide. However, during model calibration of catchment scale applications, snow parameters were generally estimated based on streamflow records rather than on snow measurements. This may lead to streamflow predictions with wrong snow melt contribution. This work highlights the importance of considering snow measurements in the calibration of the SWAT model for alpine hydrology and compares various calibration methodologies. In addition to discharge records, snow water equivalent time series of both subbasin scale and monitoring station were also utilized to evaluate the model performance by comparing with the SWAT subbasin and elevation band snow outputs. Comparing model results obtained calibrating the model using discharge data only and discharge data along with snow water equivalent data, we show that the latter approach allows us to improve the reliability of snow simulations while maintaining good estimations of streamflow. With a more reliable representation of snow dynamics, the hydrological model can provide more accurate references for proposing adequate water management solutions. This study offers to the wide SWAT user community an effective approach to improve streamflow predictions in alpine catchments and hence support decision makers in water allocation.

  3. Navigation of guidewires and catheters in the body during intervention procedures : A review of computer-based models

    NARCIS (Netherlands)

    Sharei Amarghan, H.; Alderliesten, Tanja; van den Dobbelsteen, J.J.; Dankelman, J.

    2018-01-01

    Guidewires and catheters are used during minimally invasive interventional procedures to traverse in vascular system and access the desired position. Computer models are increasingly being used to predict the behavior of these instruments. This information can be used to choose the right

  4. A Policy Model for Use of Aversive and Deprivation Procedures to Decrease Problem Behaviors of Students in Special Education.

    Science.gov (United States)

    Braaten, Sheldon

    1991-01-01

    A draft policy developed by the Minneapolis (Minnesota) public schools concerning the use of aversive or deprivation procedures with students who are handicapped is presented. The policy model covers such elements as response to prior interventions; written treatment plan; informed consent; supervision; maintenance and retention of records;…

  5. Evaluation of a novel, hybrid model (Mumbai EUS II) for stepwise teaching and training in EUS-guided biliary drainage and rendezvous procedures

    Science.gov (United States)

    Dhir, Vinay; Itoi, Takao; Pausawasdi, Nonthalee; Khashab, Mouen A.; Perez-Miranda, Manuel; Sun, Siyu; Park, Do Hyun; Iwashita, Takuji; Teoh, Anthony Y. B.; Maydeo, Amit P.; Ho, Khek Yu

    2017-01-01

    Background and aims  EUS-guided biliary drainage (EUS-BD) and rendezvous (EUS-RV) are acceptable rescue options for patients with failed endoscopic retrograde cholangiopancreatography (ERCP). However, there are limited training opportunities at most centers owing to low case volumes. The existing models do not replicate the difficulties encountered during EUS-BD. We aimed to develop and validate a model for stepwise learning of EUS-BD and EUS-RV, which replicates the actual EUS-BD procedures. Methods  A hybrid model was created utilizing pig esophagus and stomach, with a synthetic duodenum and biliary system. The model was objectively assessed on a grade of 1 – 4 by two experts. Twenty-eight trainees were given initial training with didactic lectures and live procedures. This was followed by hands-on training in EUS-BD and EUS-RV on the hybrid model. Trainees were assessed for objective criteria of technical difficulties. Results  Both the experts graded the model as very good or above for all parameters. All trainees could complete the requisite steps of EUS-BD and EUS-RV in a mean time of 11 minutes (8 – 18 minutes). Thirty-six technical difficulties were noted during the training (wrong scope position, 13; incorrect duct puncture, 12; guidewire related problems, 11). Technical difficulties peaked for EUS-RV, followed by hepaticogastrostomy (HGS) and choledochoduodenostomy (CDS) (20, 9, and 7, P  = 0.001). At 10 days follow-up, nine of 28 trainees had successfully performed three EUS-RV and seven EUS-BD procedures independently. Conclusions  The Mumbai EUS II hybrid model replicates situations encountered during EUS-RV and EUS-BD. Stepwise mentoring improves the chances of success in EUS-RV and EUS-BD procedures. PMID:29250585

  6. New analytic results for speciation times in neutral models.

    Science.gov (United States)

    Gernhard, Tanja

    2008-05-01

    In this paper, we investigate the standard Yule model, and a recently studied model of speciation and extinction, the "critical branching process." We develop an analytic way-as opposed to the common simulation approach-for calculating the speciation times in a reconstructed phylogenetic tree. Simple expressions for the density and the moments of the speciation times are obtained. Methods for dating a speciation event become valuable, if for the reconstructed phylogenetic trees, no time scale is available. A missing time scale could be due to supertree methods, morphological data, or molecular data which violates the molecular clock. Our analytic approach is, in particular, useful for the model with extinction, since simulations of birth-death processes which are conditioned on obtaining n extant species today are quite delicate. Further, simulations are very time consuming for big n under both models.

  7. Box photosynthesis modeling results for WRF/CMAQ LSM

    Data.gov (United States)

    U.S. Environmental Protection Agency — Box Photosynthesis model simulations for latent heat and ozone at 6 different FLUXNET sites. This dataset is associated with the following publication: Ran, L., J....

  8. Measurement of Thermal Properties of Growing Media for Green Roofs: Assessment of a Laboratory Procedure and Experimental Results

    Directory of Open Access Journals (Sweden)

    Benedetta Barozzi

    2017-10-01

    Full Text Available While the Italian standard UNI 11235:2015 establishes minimum performance criteria, the thermal resistance of the growing medium of green roofs is not included in national regulations. Instead, thermal transmittance limits for roofs are obtained by referring to other stratigraphic layers. In the absence of specific national and international standards for laboratory calculations of the thermal performance of growing media for green roofs, a multi-year laboratory testing campaign was carried out on 8 samples which aimed to define the thermal resistance reference values of growing media as a function of density and water content. Thermal conductivity varies between 0.046–0.179 W/mK for dry samples as a function of density and between 0.046–0.47 W/mK as a function of moisture content. Defining a reference method, laboratory tests and restitution of the output in performance curves, was based on 108 tests carried out according to and deviating from the standard based on both guarded hot plate and heat flow meter methods. The significance of the results has prompted researchers and industrial partners to engage in further investment and ongoing tests in this area, targeting the definition of a standard laboratory method to be presented worldwide.

  9. New Results in Optical Modelling of Quantum Well Solar Cells

    Directory of Open Access Journals (Sweden)

    Silvian Fara

    2012-01-01

    Full Text Available This project brought further advancements to the quantum well solar cell concept proposed by Keith Barnham. In this paper, the optical modelling of MQW solar cells was analyzed and we focussed on the following topics: (i simulation of the refraction index and the reflectance, (ii simulation of the absorption coefficient, (iii simulation of the quantum efficiency for the absorption process, (iv discussion and modelling of the quantum confinement effect, and (v evaluation of datasheet parameters of the MQW cell.

  10. Some Econometric Results for the Blanchard-Watson Bubble Model

    DEFF Research Database (Denmark)

    Johansen, Soren; Lange, Theis

    The purpose of the present paper is to analyse a simple bubble model suggested by Blanchard and Watson. The model is defined by y(t) =s(t)¿y(t-1)+e(t), t=1,…,n, where s(t) is an i.i.d. binary variable with p=P(s(t)=1), independent of e(t) i.i.d. with mean zero and finite variance. We take ¿>1 so ...

  11. Impact of the volume of gaseous phase in closed reactors on ANC results and modelling

    Science.gov (United States)

    Drapeau, Clémentine; Delolme, Cécile; Lassabatere, Laurent; Blanc, Denise

    2016-04-01

    The understanding of the geochemical behavior of polluted solid materials is often challenging and requires huge expenses of time and money. Nevertheless, given the increasing amounts of polluted solid materials and related risks for the environment, it is more and more crucial to understand the leaching of majors and trace metals elements from these matrices. In the designs of methods to quantify pollutant solubilization, the combination of experimental procedures with modeling approaches has recently gained attention. Among usual methods, some rely on the association of ANC and geochemical modeling. ANC experiments - Acid Neutralization Capacity - consists in adding known quantities of acid or base to a mixture of water and contaminated solid materials at a given liquid / solid ratio in closed reactors. Reactors are agitated for 48h and then pH, conductivity, redox potential, carbon, majors and heavy metal solubilized are quantified. However, in most cases, the amounts of matrix and water do not reach the total volume of reactors, leaving some space for air (gaseous phase). Despite this fact, no clear indication is given in standard procedures about the effect of this gaseous phase. Even worse, the gaseous phase is never accounted for when exploiting or modeling ANC data. The gaseous phase may exchange CO2 with the solution, which may, in turn, impact both pH and element release. This study lies within the most general framework for the use of geochemical modeling for the prediction of ANC results for the case of pure phases to real phase assemblages. In this study, we focus on the effect of the gaseous phase on ANC experiments on different mineral phases through geochemical modeling. To do so, we use PHREEQC code to model the evolution of pH and element release (including majors and heavy metals) when several matrices are put in contact with acid or base. We model the following scenarios for the gaseous phase: no gas, contact with the atmosphere (open system

  12. The animal model determines the results of Aeromonas virulence factors

    Directory of Open Access Journals (Sweden)

    Alejandro Romero

    2016-10-01

    Full Text Available The selection of an experimental animal model is of great importance in the study of bacterial virulence factors. Here, a bath infection of zebrafish larvae is proposed as an alternative model to study the virulence factors of A. hydrophila. Intraperitoneal infections in mice and trout were compared with bath infections in zebrafish larvae using specific mutants. The great advantage of this model is that bath immersion mimics the natural route of infection, and injury to the tail also provides a natural portal of entry for the bacteria. The implication of T3SS in the virulence of A. hydrophila was analysed using the AH-1::aopB mutant. This mutant was less virulent than the wild-type strain when inoculated into zebrafish larvae, as described in other vertebrates. However, the zebrafish model exhibited slight differences in mortality kinetics only observed using invertebrate models. Infections using the mutant AH-1∆vapA lacking the gene coding for the surface S-layer suggested that this protein was not totally necessary to the bacteria once it was inside the host, but it contributed to the inflammatory response. Only when healthy zebrafish larvae were infected did the mutant produce less mortality than the wild type. Variations between models were evidenced using the AH-1∆rmlB, which lacks the O-antigen lipopolysaccharide (LPS, and the AH-1∆wahD, which lacks the O-antigen LPS and part of the LPS outer-core. Both mutants showed decreased mortality in all of the animal models, but the differences between them were only observed in injured zebrafish larvae, suggesting that residues from the LPS outer core must be important for virulence. The greatest differences were observed using the AH-1ΔFlaB-J (lacking polar flagella and unable to swim and the AH-1::motX (non-motile but producing flagella. They were as pathogenic as the wild-type strain when injected into mice and trout, but no mortalities were registered in zebrafish larvae. This study

  13. Adapting a Markov Monte Carlo simulation model for forecasting the number of Coronary Artery Revascularisation Procedures in an era of rapidly changing technology and policy

    Directory of Open Access Journals (Sweden)

    Knuiman Matthew

    2008-06-01

    Full Text Available Abstract Background Treatments for coronary heart disease (CHD have evolved rapidly over the last 15 years with considerable change in the number and effectiveness of both medical and surgical treatments. This period has seen the rapid development and uptake of statin drugs and coronary artery revascularization procedures (CARPs that include Coronary Artery Bypass Graft procedures (CABGs and Percutaneous Coronary Interventions (PCIs. It is difficult in an era of such rapid change to accurately forecast requirements for treatment services such as CARPs. In a previous paper we have described and outlined the use of a Markov Monte Carlo simulation model for analyzing and predicting the requirements for CARPs for the population of Western Australia (Mannan et al, 2007. In this paper, we expand on the use of this model for forecasting CARPs in Western Australia with a focus on the lack of adequate performance of the (standard model for forecasting CARPs in a period during the mid 1990s when there were considerable changes to CARP technology and implementation policy and an exploration and demonstration of how the standard model may be adapted to achieve better performance. Methods Selected key CARP event model probabilities are modified based on information relating to changes in the effectiveness of CARPs from clinical trial evidence and an awareness of trends in policy and practice of CARPs. These modified model probabilities and the ones obtained by standard methods are used as inputs in our Markov simulation model. Results The projected numbers of CARPs in the population of Western Australia over 1995–99 only improve marginally when modifications to model probabilities are made to incorporate an increase in effectiveness of PCI procedures. However, the projected numbers improve substantially when, in addition, further modifications are incorporated that relate to the increased probability of a PCI procedure and the reduced probability of a CABG

  14. Aims and procedures used for the evaluation of research results in the field of nuclear safety with regard to the application of the Atomic Energy Law. Vol. 5

    International Nuclear Information System (INIS)

    Haehnel, G.

    1992-01-01

    The content of this report is a collection of research projects and investigations in the field of nuclear safety evaluated in 1989 and 1990 with regard to the application of the Atomic Law (Atomgesetz). In addition the report gives an overview on objectives and procedures used for the evaluation. The purpose of this project, being executed for the Federal Ministry for the Environment, Natural Conservation and Nuclear Safety of the German Federal Republic is to inform all parties involved in the licensing procedure as well as the consulting councils on the newest nuclear safety research results and the status of their verification in a precise short manner. In addition experts opinions are given with regard to the relevance of these research results to nuclear rules and guidelines as well as to the execution of the Atomic Law. The information are given by precise and short evaluations of final research reports or technical reports. These evaluations are prepared by specialists who are acquainted with the technical aspects of the licensing procedure of nuclear power plants in the German Federal Republic. (orig.) [de

  15. Aims and procedures used for the evaluation of research results in the field of nuclear safety with regard to the application of the Atomic Energy Law. Vol. 4

    International Nuclear Information System (INIS)

    Baumgaertel, K.

    1993-01-01

    The content of this report is a collection of research projects and investigations in the field of nuclear safety evaluated from April 1988 till December 1989 with regard to the application of the Atomic Law (Atomgesetz). In addition the report gives an overview on objectives and procedures used for the evaluation. The purpose of this project, being executed for the Federal Ministry for the Environment, Natural Conversation and Nuclear Safety of the German Federal Republic is to inform all parties involved in the licensing procedure as well as the consulting councils on the newest nuclear safety research results and the status of their verification in a precise short manner. In addition experts opinions are given with regard to the relevance of these research results to nuclear rules and guidelines as well as to execution of the Atomic Law. The informations are given by precise and short evaluations of final research reports or technical reports. These evaluations are prepared by specialists who are acquainted with the technical aspects of the licensing procedure of nuclear power plants in the German Federal Republic. (orig.) [de

  16. Aims and procedures used for the evaluation of research results in the field of nuclear safety with regard to the application of the Atomic Energy Law. Vol. 6

    International Nuclear Information System (INIS)

    Haehnel, G.

    1994-01-01

    The content of this report is a collection of research projects and investigations in the field of nuclear safety evaluated in 1991 and 1992 with regard to the application of the Atomic Law (Atomgesetz). In addition the report gives an overview on objectives and procedures used for the evaluation. The purpose of this project, being executed for the Federal Ministry for Environment, Natural Conservation and Nuclear Safety of the Federal Republic of Germany is to inform all parties involved in the licensing procedure as well as the consulting councils on the newest nuclear safety research results and the status of their verification in a precise short manner. In addition experts opinions are given with regard to the relevance of these research results to nuclear rules and guidelines as well as to the execution of the Atomic Law. The information are given by precise and short evaluations of final research reports or technical reports. These evaluations are prepared by specialists who are acquainted with the technical aspects of the licensing procedure of nuclear plants in the Federal Republic of Germany. This volume is the sixth report of this series. (orig.) [de

  17. Effects of autonomy-supportive and controlling styles on situational self-determined motivation: some unexpected results of the commitment procedure.

    Science.gov (United States)

    Amoura, Camille; Berjot, Sophie; Gillet, Nicolas; Caruana, Sylvain; Finez, Lucie

    2015-02-01

    Distinct and simultaneous effects of autonomy-supportive and controlling styles, usually considered as mutually exclusive, on situational self-determined motivation are tested. In Study 1, economics students (N = 100; 57 men, 43 women; M age = 21.5 yr.) were randomly assigned to one of the four experimental conditions (high vs. low) of autonomy supportive and/or controlling behaviors during a task. Results supported the independence of those constructs. An unexpected effect in regards to Self-determination Theory was found in the Low autonomy - High control condition in which self-determined motivation was observed. The interpretation for this specific condition, an effect due to the attempt to reduce cognitive dissonance triggered by the commitment procedure, was tested. In Study 2, sport students (N = 80, 44 men, 36 women; M age = 19.2 yr.) were randomly assigned to one of the three experimental conditions: No commitment, Commitment plus self-affirmation, and Commitment without self-affirmation. Results supported Study 1's interpretation: motivation was lower when participants were recruited without a commitment procedure or when they were invited to self-affirm than when participants recruited with a commitment procedure.

  18. Validating management simulation models and implications for communicating results to stakeholders

    NARCIS (Netherlands)

    Pastoors, M.A.; Poos, J.J.; Kraak, S.B.M.; Machiels, M.A.M.

    2007-01-01

    Simulations of management plans generally aim to demonstrate the robustness of the plans to assumptions about population dynamics and fleet dynamics. Such modelling is characterized by specification of an operating model (OM) representing the underlying truth and a management procedure that mimics

  19. Modeling and measuring intracellular fluxes of secreted recombinant protein in Pichia pastoris with a novel 34S labeling procedure

    Directory of Open Access Journals (Sweden)

    Hann Stephan

    2011-06-01

    Full Text Available Abstract Background The budding yeast Pichia pastoris is widely used for protein production. To determine the best suitable strategy for strain improvement, especially for high secretion, quantitative data of intracellular fluxes of recombinant protein are very important. Especially the balance between intracellular protein formation, degradation and secretion defines the major bottleneck of the production system. Because these parameters are different for unlimited growth (shake flask and carbon-limited growth (bioreactor conditions, they should be determined under "production like" conditions. Thus labeling procedures must be compatible with minimal production media and the usage of bioreactors. The inorganic and non-radioactive 34S labeled sodium sulfate meets both demands. Results We used a novel labeling method with the stable sulfur isotope 34S, administered as sodium sulfate, which is performed during chemostat culivations. The intra- and extracellular sulfur 32 to 34 ratios of purified recombinant protein, the antibody fragment Fab3H6, are measured by HPLC-ICP-MS. The kinetic model described here is necessary to calculate the kinetic parameters from sulfur ratios of consecutive samples as well as for sensitivity analysis. From the total amount of protein produced intracellularly (143.1 μg g-1 h-1 protein per yeast dry mass and time about 58% are degraded within the cell, 35% are secreted to the exterior and 7% are inherited to the daughter cells. Conclusions A novel 34S labeling procedure that enables in vivo quantification of intracellular fluxes of recombinant protein under "production like" conditions is described. Subsequent sensitivity analysis of the fluxes by using MATLAB, indicate the most promising approaches for strain improvement towards increased secretion.

  20. Results from Development of Model Specifications for Multifamily Energy Retrofits

    Energy Technology Data Exchange (ETDEWEB)

    Brozyna, K.

    2012-08-01

    Specifications, modeled after CSI MasterFormat, provide the trade contractors and builders with requirements and recommendations on specific building materials, components and industry practices that comply with the expectations and intent of the requirements within the various funding programs associated with a project. The goal is to create a greater level of consistency in execution of energy efficiency retrofits measures across the multiple regions a developer may work. IBACOS and Mercy Housing developed sample model specifications based on a common building construction type that Mercy Housing encounters.

  1. Results From Development of Model Specifications for Multifamily Energy Retrofits

    Energy Technology Data Exchange (ETDEWEB)

    Brozyna, Kevin [IBACOS, Inc., Pittsburgh, PA (United States)

    2012-08-01

    Specifications, modeled after CSI MasterFormat, provide the trade contractors and builders with requirements and recommendations on specific building materials, components and industry practices that comply with the expectations and intent of the requirements within the various funding programs associated with a project. The goal is to create a greater level of consistency in execution of energy efficiency retrofits measures across the multiple regions a developer may work. IBACOS and Mercy Housing developed sample model specifications based on a common building construction type that Mercy Housing encounters.

  2. First results obtained in France with the latest model of the Fresenius cell separator: AS 104.

    Science.gov (United States)

    Coffe, C; Couteret, Y; Devillers, M; Fest, T; Hervé, P; Kieffer, Y; Lamy, B; Masse, M; Morel, P; Pouthier-Stein, F

    1993-01-01

    In Besançon, we carried out 40 plateletphereses with the latest model of the Fresenius cell separator AS 104 to check this new system against the new generation of cell separators, according to the following criteria: less than 2x10 6 leukocytes (before filtration) and more than 5x10 11 platelets. The results show that platelet concentrates contained 5.04+/-0.88x10 11 platelets in a total volume of 435+/-113 mL. The mean platelet recovery was 40.95+/-4.86% (from 31.7 to 51.6). The leukocyte content was 2.28+/-5.48x10 6 and the red blood cell contamination was 3.48+/-2.38x10 8. The quality of the platelets was very satisfactory. There was no problem with donor biocompatibility or procedure safety, few adverse donor reactions (0.6%) and good therapeutic efficiency of platelet concentrates.

  3. Analysis of inelastic neutron scattering results on model compounds ...

    Indian Academy of Sciences (India)

    J Tomkinson heterobicyclic molecules could form a reasonable base of model compounds to un- derstand the eigenvectors of one interesting molecular system; the nitrogenous het- erocyclic bases of the nucleotides. Low energy molecular vibrational eigenvectors involve atomic displacements over the molecule as a whole ...

  4. Delta-tilde interpretation of standard linear mixed model results

    DEFF Research Database (Denmark)

    Brockhoff, Per Bruun; Amorim, Isabel de Sousa; Kuznetsova, Alexandra

    2016-01-01

    data set and compared to actual d-prime calculations based on Thurstonian regression modeling through the ordinal package. For more challenging cases we offer a generic "plug-in" implementation of a version of the method as part of the R-package SensMixed. We discuss and clarify the bias mechanisms...

  5. Some Results On The Modelling Of TSS Manufacturing Lines

    Directory of Open Access Journals (Sweden)

    Viorel MÎNZU

    2000-12-01

    Full Text Available This paper deals with the modelling of a particular class of manufacturing lines, governed by a decentralised control strategy so that they balance themselves. Such lines are known as “bucket brigades” and also as “TSS lines”, after their first implementation, at Toyota, in the 70’s. A first study of their behaviour was based upon modelling as stochastic dynamic systems, which emphasised, in the frame of the so-called “Normative Model”, a sufficient condition for self-balancing, that means for autonomous functioning at a steady production rate (stationary behaviour. Under some particular conditions, a simulation analysis of TSS lines could be made on non-linear block diagrams, showing that the state trajectories are piecewise continuous in between occurrences of certain discrete events, which determine their discontinuity. TSS lines may therefore be modelled as hybrid dynamic systems, more specific, with autonomous switching and autonomous impulses (jumps. A stability analysis of such manufacturing lines is allowed by modelling them as hybrid dynamic systems with discontinuous motions.

  6. Some results for the dynamic (s, S) inventory model *

    NARCIS (Netherlands)

    H.C. Tijms

    1971-01-01

    textabstractSummary The periodic review, single item, stationary (s, S) inventory model is considered. There is a fixed lead time, a linear purchase cost, a fixed set‐up cost, a holding and shortage cost function, a discount factor 0 < α≤ 1 and backlogging of unfilled demand. The solution for the

  7. Recent numerical results on the two dimensional Hubbard model

    Energy Technology Data Exchange (ETDEWEB)

    Parola, A.; Sorella, S.; Baroni, S.; Car, R.; Parrinello, M.; Tosatti, E. (SISSA, Trieste (Italy))

    1989-12-01

    A new method for simulating strongly correlated fermionic systems, has been applied to the study of the ground state properties of the 2D Hubbard model at various fillings. Comparison has been made with exact diagonalizations in the 4 x 4 lattices where very good agreement has been verified in all the correlation functions which have been studied: charge, magnetization and momentum distribution. (orig.).

  8. Analytical results for the Sznajd model of opinion formation

    Czech Academy of Sciences Publication Activity Database

    Slanina, František; Lavička, H.

    2003-01-01

    Roč. 35, - (2003), s. 279-288 ISSN 1434-6028 R&D Projects: GA ČR GA202/01/1091 Institutional research plan: CEZ:AV0Z1010914 Keywords : agent models * sociophysics Subject RIV: BE - Theoretical Physics Impact factor: 1.457, year: 2003

  9. Design Procedure Enhanced with Numerical Modeling to Mitigate River-Bank Erosion

    Directory of Open Access Journals (Sweden)

    Elhakeem Mohamed

    2016-01-01

    Full Text Available In this study, the 2D Finite Element Surface Water Modeling System (FESWMS is used to design barb structures to mitigate river bank erosion in a stream reach located on the Raccoon River near Adel, Iowa, USA just upstream of the US Highway Bridge 169. FESWMS is used also to access the barbs effect on the study reach. The model results showed that the proposed barb structures successfully reduced the flow velocity along the outside bank and increased the velocity in the center of the stream, thereby successfully increased the conveyance towards the core of the river. The estimated velocities values along the river-banks where the barbs exist were within the recommended values for channel stability design. Thus, the barb structures were able to reduce the erosion along the bankline.

  10. Modeling of precipitation and Cr depletion profiles of Inconel 600 during heat treatments and LSM procedure

    Energy Technology Data Exchange (ETDEWEB)

    Bao Gang [Department of Mechanical System Engineering, Hiroshima University, 1-4-1 Higashi-Hiroshima, Hiroshima (Japan); Shinozaki, Kenji [Department of Mechanical System Engineering, Hiroshima University, 1-4-1 Higashi-Hiroshima, Hiroshima (Japan)]. E-mail: kshino@hiroshima-u.ac.jp; Inkyo, Muneyuki [Department of Mechanical System Engineering, Hiroshima University, 1-4-1 Higashi-Hiroshima, Hiroshima (Japan); Miyoshi, Tomohisa [Department of Mechanical System Engineering, Hiroshima University, 1-4-1 Higashi-Hiroshima, Hiroshima (Japan); Yamamoto, Motomichi [Department of Mechanical System Engineering, Hiroshima University, 1-4-1 Higashi-Hiroshima, Hiroshima (Japan); Mahara, Yoichi [Babcock-Hitachi K.K., 3-36 Takara-machi, Kure, Hiroshima (Japan); Watanabe, Hiroshi [Babcock-Hitachi K.K., 3-36 Takara-machi, Kure, Hiroshima (Japan)

    2006-08-10

    A model based on the thermodynamic and kinetic was conducted to simulate the Cr depletion profiles near the grain boundary in Inconel 600 during the heat treatments and laser surface melting (LSM) process using Thermo-Calc and Dictra code. Based on the good agreement of Cr concentration distribution during heat treatments measured by experiments, the microsegregation of Cr induced by cellular microstructure formed during the LSM process was also modeled. The Cr depletion profile was evaluated using the Cr depletion area below the critical Cr concentration for intergranular cracking/intergranular stress corrosion cracking (IGC/IGSCC) susceptibility (8 mass%). Comparing with the result of Streicher test, the Cr depletion area calculated showed good coherence with the IGC/IGSCC susceptibility. The sample after SR + LTS treatment with the largest Cr depletion area showed the worst IGC/IGSCC resistance, while, the sample after LSM process with the smaller Cr depletion area showed the excellent IGC/IGSCC resistance.

  11. Acucise™ endopyelotomy in a porcine model: procedure standardization and analysis of safety and immediate efficacy

    Directory of Open Access Journals (Sweden)

    Andreoni Cássio

    2004-01-01

    Full Text Available PURPOSE: The study here presented was done to test the technical reliability and immediate efficacy of the Acucise device using a standardized technique. MATERIALS AND METHODS: 56 Acucise procedures were performed in pigs by a single surgeon who used a standardized technique: insert 5F angiographic catheter bilaterally up to the midureter, perform retrograde pyelogram, Amplatz super-stiff guidewire is advanced up to the level of the renal pelvis, angiographic catheters are removed, Acucise catheter balloon is advanced to the ureteropelvic junction (UPJ level, the super-stiff guide-wire is removed and the contrast medium in the renal pelvis is aspirated and replaced with distilled water, activate Acucise at 75 watts of pure cutting current, keep the balloon fully inflated for 10 minutes, perform retrograde ureteropyelogram to document extravasation, remove Acucise catheter and pass an ureteral stent and remove guide-wire. RESULTS: In no case did the Acucise device present malfunction. The electrocautery activation time was 2.2 seconds (ranging from 2 to 4 seconds. The extravasation of contrast medium, visible by fluoroscopy, occurred in 53 of the 56 cases (94.6%. In no case there was any evidence of intraoperative hemorrhage. CONCLUSIONS: This study revealed that performing Acucise endopyelotomy routinely in a standardized manner could largely preclude intraoperative device malfunction and eliminate complications while achieving a successful incision in the UPJ. With the guidelines that were used in this study, we believe that Acucise endopyelotomy can be completed successfully and safely in the majority of selected patients with UPJ obstruction.

  12. Regionalization of climate model results for the North Sea

    Energy Technology Data Exchange (ETDEWEB)

    Kauker, F. [Alfred-Wegener-Institut fuer Polar- und Meeresforschung, Bremerhaven (Germany); Storch, H. von [GKSS-Forschungszentrum Geesthacht GmbH (Germany). Inst. fuer Hydrophysik

    2000-07-01

    A dynamical downscaling for the North Sea is presented. The numerical model used for the study is the coupled ice-ocean model OPYC. In a hindcast of the years 1979 to 1993 it was forced with atmospheric forcing of the ECMWF reanalysis. The models capability in simulating the observed mean state and variability in the North Sea is demonstrated by the hindcast. Two time scale ranges, from weekly to seasonal and the longer-than-seasonal time scales are investigated. Shorter time scales, for storm surges, are not captured by the model formulation. The main modes of variability of sea level, sea-surface circulation, sea-surface temperature, and sea-surface salinity are described and connections to atmospheric phenomena, like the NAO, are discussed. T106 ''time-slice'' simulations with a ''2 x CO{sub 2}'' horizon are used to estimate the effects of a changing climate on the shelf sea ''North Sea''. The ''2 x CO{sub 2}'' changes in the surface forcing are accompanied by changes in the lateral oceanic boundary conditions taken from a global coupled climate model. For ''2 x CO{sub 2}'' the time mean sea level increases up to 25 cm in the German Bight in the winter, where 15 cm are due to the surface forcing and 10 cm due to thermal expansion. This change is compared to the ''natural'' variability as simulated in the ECMWF integration and found to be not outside the range spanned by it. The variability of sea level on the weekly-to-seasonal time-scales is significantly reduced in the scenario integration. The variability on the longer-than-seasonal time-scales in the control and scenario runs is much smaller then in the ECMWF integration. This is traced back to the use of ''time-slice'' experiments. Discriminating between locally forced changes and changes induced at the lateral oceanic boundaries of the model in the circulation and

  13. An Introduction to the Model of Crisis Intervention Procedure for Borderline Patients (CIP-BP): A Case Study.

    Science.gov (United States)

    Koweszko, Tytus; Gierus, Jacek; Więdłocha, Magdalena; Mosiołek, Anna; Szulc, Agata

    2017-06-01

    Borderline personality disorder is highly associated with suicidal behaviors. The authors of the current case study present the introduction model of original Crisis Intervention Procedure for Borderline Patients (CIP-BP) which is a method focused on restoring emotional balance, reducing the severity of symptoms and the risk of suicidal behavior, as well as developing optimum solutions for further action. Its aim is to enable the patient to regain control of their emotional memory, increase autonomy and restore important interpersonal relations by using the original resources of this person. The procedure aims at providing nursing personnel with a practical tool to effectively avert the crisis and prevent further decompensation of BPD patients. Further pre-post study is required to determine the effectiveness of the procedure. Copyright © 2017 Elsevier Inc. All rights reserved.

  14. Dynamic model of the electrorheological fluid based on measurement results

    International Nuclear Information System (INIS)

    Krivenkov, K; Ulrich, S; Bruns, R

    2013-01-01

    To develop modern applications for vibration decoupling based on electrorheological fluids with suitable control strategies, an appropriate mathematical model of the ERF is necessary. The devices mostly used have annular-shape electrorheological valves. This requires the use of flow channels to measure the static and dynamic properties of the electrorheological fluids in similar flow conditions. Particularly for the identification of the dynamic behavior of the fluids, the influences of the non-electrorheological properties on the overall system must be taken into account. In this contribution three types of parameters with several nonlinear dependencies for the mapping of the static and dynamic properties of the ERF are considered: electro-rheological, hydraulic and electrical. The mathematical model introduced can precisely demonstrate the static and dynamic behavior of the electrorheological fluid and can be used for the future design of real systems for vibration decoupling or other systems with high dynamic requirements.

  15. 1-g model loading tests: methods and results

    Czech Academy of Sciences Publication Activity Database

    Feda, Jaroslav

    1999-01-01

    Roč. 2, č. 4 (1999), s. 371-381 ISSN 1436-6517. [Int.Conf. on Soil - Structure Interaction in Urban Civ. Engineering. Darmstadt, 08.10.1999-09.10.1999] R&D Projects: GA MŠk OC C7.10 Keywords : shallow foundation * model tests * sandy subsoil * bearing capacity * subsoil failure * volume deformation Subject RIV: JM - Building Engineering

  16. Sharing brain mapping statistical results with the neuroimaging data model

    Science.gov (United States)

    Maumet, Camille; Auer, Tibor; Bowring, Alexander; Chen, Gang; Das, Samir; Flandin, Guillaume; Ghosh, Satrajit; Glatard, Tristan; Gorgolewski, Krzysztof J.; Helmer, Karl G.; Jenkinson, Mark; Keator, David B.; Nichols, B. Nolan; Poline, Jean-Baptiste; Reynolds, Richard; Sochat, Vanessa; Turner, Jessica; Nichols, Thomas E.

    2016-01-01

    Only a tiny fraction of the data and metadata produced by an fMRI study is finally conveyed to the community. This lack of transparency not only hinders the reproducibility of neuroimaging results but also impairs future meta-analyses. In this work we introduce NIDM-Results, a format specification providing a machine-readable description of neuroimaging statistical results along with key image data summarising the experiment. NIDM-Results provides a unified representation of mass univariate analyses including a level of detail consistent with available best practices. This standardized representation allows authors to relay methods and results in a platform-independent regularized format that is not tied to a particular neuroimaging software package. Tools are available to export NIDM-Result graphs and associated files from the widely used SPM and FSL software packages, and the NeuroVault repository can import NIDM-Results archives. The specification is publically available at: http://nidm.nidash.org/specs/nidm-results.html. PMID:27922621

  17. DISCRETE DEFORMATION WAVE DYNAMICS IN SHEAR ZONES: PHYSICAL MODELLING RESULTS

    Directory of Open Access Journals (Sweden)

    S. A. Bornyakov

    2016-01-01

    Full Text Available Observations of earthquake migration along active fault zones [Richter, 1958; Mogi, 1968] and related theoretical concepts [Elsasser, 1969] have laid the foundation for studying the problem of slow deformation waves in the lithosphere. Despite the fact that this problem has been under study for several decades and discussed in numerous publications, convincing evidence for the existence of deformation waves is still lacking. One of the causes is that comprehensive field studies to register such waves by special tools and equipment, which require sufficient organizational and technical resources, have not been conducted yet.The authors attempted at finding a solution to this problem by physical simulation of a major shear zone in an elastic-viscous-plastic model of the lithosphere. The experiment setup is shown in Figure 1 (A. The model material and boundary conditions were specified in accordance with the similarity criteria (described in detail in [Sherman, 1984; Sherman et al., 1991; Bornyakov et al., 2014]. The montmorillonite clay-and-water paste was placed evenly on two stamps of the installation and subject to deformation as the active stamp (1 moved relative to the passive stamp (2 at a constant speed. The upper model surface was covered with fine sand in order to get high-contrast photos. Photos of an emerging shear zone were taken every second by a Basler acA2000-50gm digital camera. Figure 1 (B shows an optical image of a fragment of the shear zone. The photos were processed by the digital image correlation method described in [Sutton et al., 2009]. This method estimates the distribution of components of displacement vectors and strain tensors on the model surface and their evolution over time [Panteleev et al., 2014, 2015].Strain fields and displacements recorded in the optical images of the model surface were estimated in a rectangular box (220.00×72.17 mm shown by a dot-and-dash line in Fig. 1, A. To ensure a sufficient level of

  18. Determination of a Differential Item Functioning Procedure Using the Hierarchical Generalized Linear Model

    Directory of Open Access Journals (Sweden)

    Tülin Acar

    2012-01-01

    Full Text Available The aim of this research is to compare the result of the differential item functioning (DIF determining with hierarchical generalized linear model (HGLM technique and the results of the DIF determining with logistic regression (LR and item response theory–likelihood ratio (IRT-LR techniques on the test items. For this reason, first in this research, it is determined whether the students encounter DIF with HGLM, LR, and IRT-LR techniques according to socioeconomic status (SES, in the Turkish, Social Sciences, and Science subtest items of the Secondary School Institutions Examination. When inspecting the correlations among the techniques in terms of determining the items having DIF, it was discovered that there was significant correlation between the results of IRT-LR and LR techniques in all subtests; merely in Science subtest, the results of the correlation between HGLM and IRT-LR techniques were found significant. DIF applications can be made on test items with other DIF analysis techniques that were not taken to the scope of this research. The analysis results, which were determined by using the DIF techniques in different sample sizes, can be compared.

  19. A rainfall disaggregation scheme for sub-hourly time scales: Coupling a Bartlett-Lewis based model with adjusting procedures

    Science.gov (United States)

    Kossieris, Panagiotis; Makropoulos, Christos; Onof, Christian; Koutsoyiannis, Demetris

    2018-01-01

    Many hydrological applications, such as flood studies, require the use of long rainfall data at fine time scales varying from daily down to 1 min time step. However, in the real world there is limited availability of data at sub-hourly scales. To cope with this issue, stochastic disaggregation techniques are typically employed to produce possible, statistically consistent, rainfall events that aggregate up to the field data collected at coarser scales. A methodology for the stochastic disaggregation of rainfall at fine time scales was recently introduced, combining the Bartlett-Lewis process to generate rainfall events along with adjusting procedures to modify the lower-level variables (i.e., hourly) so as to be consistent with the higher-level one (i.e., daily). In the present paper, we extend the aforementioned scheme, initially designed and tested for the disaggregation of daily rainfall into hourly depths, for any sub-hourly time scale. In addition, we take advantage of the recent developments in Poisson-cluster processes incorporating in the methodology a Bartlett-Lewis model variant that introduces dependence between cell intensity and duration in order to capture the variability of rainfall at sub-hourly time scales. The disaggregation scheme is implemented in an R package, named HyetosMinute, to support disaggregation from daily down to 1-min time scale. The applicability of the methodology was assessed on a 5-min rainfall records collected in Bochum, Germany, comparing the performance of the above mentioned model variant against the original Bartlett-Lewis process (non-random with 5 parameters). The analysis shows that the disaggregation process reproduces adequately the most important statistical characteristics of rainfall at wide range of time scales, while the introduction of the model with dependent intensity-duration results in a better performance in terms of skewness, rainfall extremes and dry proportions.

  20. Downtime procedures for the 21st century: using a fully integrated health record for uninterrupted electronic reporting of laboratory results during laboratory information system downtimes.

    Science.gov (United States)

    Oral, Bulent; Cullen, Regina M; Diaz, Danny L; Hod, Eldad A; Kratz, Alexander

    2015-01-01

    Downtimes of the laboratory information system (LIS) or its interface to the electronic medical record (EMR) disrupt the reporting of laboratory results. Traditionally, laboratories have relied on paper-based or phone-based reporting methods during these events. We developed a novel downtime procedure that combines advance placement of orders by clinicians for planned downtimes, the printing of laboratory results from instruments, and scanning of the instrument printouts into our EMR. The new procedure allows the analysis of samples from planned phlebotomies with no delays, even during LIS downtimes. It also enables the electronic reporting of all clinically urgent results during downtimes, including intensive care and emergency department samples, thereby largely avoiding paper- and phone-based communication of laboratory results. With the capabilities of EMRs and LISs rapidly evolving, information technology (IT) teams, laboratories, and clinicians need to collaborate closely, review their systems' capabilities, and design innovative ways to apply all available IT functions to optimize patient care during downtimes. Copyright© by the American Society for Clinical Pathology.

  1. The Next Step in Deployment of Computer Based Procedures For Field Workers: Insights And Results From Field Evaluations at Nuclear Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    Oxstrand, Johanna; Le Blanc, Katya L.; Bly, Aaron

    2015-02-01

    The paper-based procedures currently used for nearly all activities in the commercial nuclear power industry have a long history of ensuring safe operation of the plants. However, there is potential to greatly increase efficiency and safety by improving how the human operator interacts with the procedures. One way to achieve these improvements is through the use of computer-based procedures (CBPs). A CBP system offers a vast variety of improvements, such as context driven job aids, integrated human performance tools (e.g., placekeeping, correct component verification, etc.), and dynamic step presentation. The latter means that the CBP system could only display relevant steps based on operating mode, plant status, and the task at hand. A dynamic presentation of the procedure (also known as context-sensitive procedures) will guide the operator down the path of relevant steps based on the current conditions. This feature will reduce the operator’s workload and inherently reduce the risk of incorrectly marking a step as not applicable and the risk of incorrectly performing a step that should be marked as not applicable. The research team at the Idaho National Laboratory has developed a prototype CBP system for field workers, which has been evaluated from a human factors and usability perspective in four laboratory studies. Based on the results from each study revisions were made to the CBP system. However, a crucial step to get the end users' (e.g., auxiliary operators, maintenance technicians, etc.) acceptance is to put the system in their hands and let them use it as a part of their everyday work activities. In the spring 2014 the first field evaluation of the INL CBP system was conducted at a nuclear power plant. Auxiliary operators conduct a functional test of one out of three backup air compressors each week. During the field evaluation activity, one auxiliary operator conducted the test with the paper-based procedure while a second auxiliary operator

  2. MCNP Modeling Results for Location of Buried TRU Waste Drums

    International Nuclear Information System (INIS)

    Steinman, D K; Schweitzer, J S

    2006-01-01

    In the 1960's, fifty-five gallon drums of TRU waste were buried in shallow pits on remote U.S. Government facilities such as the Idaho National Engineering Laboratory (now split into the Idaho National Laboratory and the Idaho Completion Project [ICP]). Subsequently, it was decided to remove the drums and the material that was in them from the burial pits and send the material to the Waste Isolation Pilot Plant in New Mexico. Several technologies have been tried to locate the drums non-intrusively with enough precision to minimize the chance for material to be spread into the environment. One of these technologies is the placement of steel probe holes in the pits into which wireline logging probes can be lowered to measure properties and concentrations of material surrounding the probe holes for evidence of TRU material. There is also a concern that large quantities of volatile organic compounds (VOC) are also present that would contaminate the environment during removal. In 2001, the Idaho National Engineering and Environmental Laboratory (INEEL) built two pulsed neutron wireline logging tools to measure TRU and VOC around the probe holes. The tools are the Prompt Fission Neutron (PFN) and the Pulsed Neutron Gamma (PNG), respectively. They were tested experimentally in surrogate test holes in 2003. The work reported here estimates the performance of the tools using Monte-Carlo modelling prior to field deployment. A MCNP model was constructed by INEEL personnel. It was modified by the authors to assess the ability of the tools to predict quantitatively the position and concentration of TRU and VOC materials disposed around the probe holes. The model was used to simulate the tools scanning the probe holes vertically in five centimetre increments. A drum was included in the model that could be placed near the probe hole and at other locations out to forty-five centimetres from the probe-hole in five centimetre increments. Scans were performed with no chlorine in the

  3. NASA Air Force Cost Model (NAFCOM): Capabilities and Results

    Science.gov (United States)

    McAfee, Julie; Culver, George; Naderi, Mahmoud

    2011-01-01

    NAFCOM is a parametric estimating tool for space hardware. Uses cost estimating relationships (CERs) which correlate historical costs to mission characteristics to predict new project costs. It is based on historical NASA and Air Force space projects. It is intended to be used in the very early phases of a development project. NAFCOM can be used at the subsystem or component levels and estimates development and production costs. NAFCOM is applicable to various types of missions (crewed spacecraft, uncrewed spacecraft, and launch vehicles). There are two versions of the model: a government version that is restricted and a contractor releasable version.

  4. Solar activity variations of ionosonde measurements and modeling results

    Czech Academy of Sciences Publication Activity Database

    Altadill, D.; Arrazola, D.; Blanch, E.; Burešová, Dalia

    2008-01-01

    Roč. 42, č. 4 (2008), s. 610-616 ISSN 0273-1177 R&D Projects: GA AV ČR 1QS300120506 Grant - others:MCYT(ES) REN2003-08376-C02-02; CSIC(XE) 2004CZ0002; AGAUR(XE) 2006BE00112; AF Research Laboratory(XE) FA8718-L-0072 Institutional research plan: CEZ:AV0Z30420517 Keywords : mid-latitude ionosphere * bottomside modeling * ionospheric variability Subject RIV: DG - Athmosphere Sciences, Meteorology Impact factor: 0.860, year: 2008 http://www.sciencedirect.com/science/journal/02731177

  5. An Analysis of Bid Evaluation Procedures of Contemporary Models for Procurement in Pakistan

    Science.gov (United States)

    2016-12-01

    one company . In this procedure, contracting agency does not have to announce or advertise the procurement (Turkish Public Procurement Law , 2002...prosper them according to the related laws in Turkish public procurement system. This rule can only be used to support the local companies . There is...Commonwealth Procurement Rules. (2014). Public Procurement Law of Australia . Consult Australia . (2015). Economic benefits of better procurement

  6. Digital human modelling systems : A procedure for verification and validation using the F-16 crew station

    NARCIS (Netherlands)

    Hudson, J.A.; Oudenhuijzen, A.J.K.; Zehner, G.F.

    2000-01-01

    Mensmodellen worden veelal toegepast bij het ontwerpen en testen van werkplekken. Echter de nauwkeurigheid van de systemen is niet bekend. Er is dan een kans dat er (dure) fouten worden gemaakt. Om achter die nauwkeurigheid te komen is een procedure opgesteld om mensmodellen te testen

  7. New directional results and determination of absolute archaeointensity using both the classical Thellier and the multi-specimen procedures for two kilns excavated at Osterietta, Italy

    Science.gov (United States)

    Tema, Evdokia; Camps, Pierre; Ferrara, Enzo

    2014-05-01

    A detailed rock-magnetic and archaeomagnetic study has been carried out on two rescue excavation kilns discovered during the works to expand a highway at the location of Osterietta, in Northen Italy. Systematic archaeomagnetic sampling was carried out collecting 15 samples from the first kiln (OSA) and 8 samples from the second kiln (OSB), all of them oriented in situ with a magnetic compass and an inclinometer. Magnetic mineralogy measurements have been carried out in order to determine the main magnetic carrier of the samples and to check their thermal stability. Standard thermal demagnetization procedures have been used to determine the archaeomagnetic direction registered by the bricks during their last firing. Demagnetization results show a very stable characteristic remanent magnetization (ChRM). We averaged the directions for each kiln separately and calculated the statistical parameters assuming a Fisherian distribution. The archaeointensity of both kilns has also been recovered with both the classical Thellier-Thellier method and the multi-specimen procedure (MSP-DSC). During the Thellier experiments, regular partial thermoremanent magnetization checks have been performed and the effect of the anisotropy of the thermoremanent magnetization (TRM) and cooling rate upon TRM intensity acquisition have been investigated in all samples. The multi-specimen procedure was performed with a very fast-heating oven developed at Montpellier (France). The intensity results obtained from both methods have been compared and the full geomagnetic field vector determined for each kiln has been used for archaeomagnetic dating. The obtained results show that the kilns were almost contemporaneous and their last use occurred in the 1750-1850 AD time interval.

  8. A Generic Procedure for the Assessment of the Effect of Concrete Admixtures on the Sorption of Radionuclides on Cement: Concept and Selected Results

    International Nuclear Information System (INIS)

    Glaus, M.A.; Laube, A.; Van Loon, L.R.

    2004-01-01

    A screening procedure is proposed for the assessment of the effect of concrete admixtures on the sorption of radionuclides by cement. The procedure is both broad and generic, and can thus be used as input for the assessment of concrete admixtures which might be used in the future. The experimental feasibility and significance of the screening procedure are tested using selected concrete admixtures: i.e. sulfonated naphthalene-formaldehyde condensates, lignosulfonates, and a plasticiser used at PSI for waste conditioning. The effect of these on the sorption properties of Ni(II), Eu(III) and Th(IV) in cement is investigated using crushed Hardened Cement Paste (HCP), as well as cement pastes prepared in the presence of these admixtures. Strongly adverse effects on the sorption of the radionuclides tested are observed only in single cases, and under extreme conditions: i.e. at high ratios of concrete admixtures to HCP, and at low ratios of HCP to cement pore water. Under realistic conditions, both radionuclide sorption and the sorption of isosaccharinic acid (a strong complexant produced in cement-conditioned wastes containing cellulose) remain unaffected by the presence of concrete admixtures, which can be explained by the sorption of them onto the HCP. The pore-water concentrations of the concrete admixtures tested are thereby reduced to levels at which the formation of radionuclide complexes is no longer of importance. Further, the Langmuir sorption model, proposed for the sorption of concrete admixtures on HCP, suggests that the HCP surface does not become saturated, at least for those concrete admixtures tested. (author)

  9. A Generic Procedure for the Assessment of the Effect of Concrete Admixtures on the Sorption of Radionuclides on Cement: Concept and Selected Results

    Energy Technology Data Exchange (ETDEWEB)

    Glaus, M.A.; Laube, A.; Van Loon, L.R

    2004-03-01

    A screening procedure is proposed for the assessment of the effect of concrete admixtures on the sorption of radionuclides by cement. The procedure is both broad and generic, and can thus be used as input for the assessment of concrete admixtures which might be used in the future. The experimental feasibility and significance of the screening procedure are tested using selected concrete admixtures: i.e. sulfonated naphthalene-formaldehyde condensates, lignosulfonates, and a plasticiser used at PSI for waste conditioning. The effect of these on the sorption properties of Ni(II), Eu(III) and Th(IV) in cement is investigated using crushed Hardened Cement Paste (HCP), as well as cement pastes prepared in the presence of these admixtures. Strongly adverse effects on the sorption of the radionuclides tested are observed only in single cases, and under extreme conditions: i.e. at high ratios of concrete admixtures to HCP, and at low ratios of HCP to cement pore water. Under realistic conditions, both radionuclide sorption and the sorption of isosaccharinic acid (a strong complexant produced in cement-conditioned wastes containing cellulose) remain unaffected by the presence of concrete admixtures, which can be explained by the sorption of them onto the HCP. The pore-water concentrations of the concrete admixtures tested are thereby reduced to levels at which the formation of radionuclide complexes is no longer of importance. Further, the Langmuir sorption model, proposed for the sorption of concrete admixtures on HCP, suggests that the HCP surface does not become saturated, at least for those concrete admixtures tested. (author)

  10. Combining forming results via weld models to powerful numerical assemblies

    NARCIS (Netherlands)

    Kose, K.; Rietman, Bert

    2004-01-01

    Forming simulations generally give satisfying results with respect to thinning, stresses, changed material properties and, with a proper springback calculation, the geometric form. The joining of parts by means of welding yields an extra change of the material properties and the residual stresses.

  11. Percutaneous Treatment of Simple Hepatic Cysts: The Long-Term Results of PAIR and Catheterization Techniques as Single-Session Procedures

    Energy Technology Data Exchange (ETDEWEB)

    Akhan, Okan, E-mail: akhano@tr.net [Hacettepe University Faculty of Medicine, Department of Radiology (Turkey); Islim, Filiz, E-mail: fislim@yahoo.com [Istanbul Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Department of Radiology (Turkey); Balci, Sinan, E-mail: snnbalci@gmail.com [Hacettepe University Faculty of Medicine, Department of Radiology (Turkey); Erbahceci, Aysun, E-mail: aysunerbahceci@yahoo.com [Istanbul Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Department of Radiology (Turkey); Akpınar, Burcu, E-mail: burcu-akpinar@yahoo.com; Ciftci, Turkmen, E-mail: turkmenciftci@yahoo.com; Akinci, Devrim, E-mail: akincid@hotmail.com [Hacettepe University Faculty of Medicine, Department of Radiology (Turkey)

    2016-06-15

    PurposeThe purpose of our study is to evaluate results of percutaneous aspiration with alcohol sclerotherapy in symptomatic patients with simple hepatic cysts by employing single-session techniques either by a needle or a catheter.Materials and MethodsWe retrospectively included 39 simple hepatic cysts in 35 patients treated via percutaneous aspiration and single-session alcohol sclerotherapy between years 1993 and 2012. Indications were pain (n = 28) or ruling out cystic echinococcus (CE) disease (n = 7). 29 cysts in 26 patients were treated by needle technique (Group A) and ten cysts in nine patients were treated by single-session catheter technique (Group B). Patients were followed for 4–173 months (median: 38 months).ResultsAll patients were successfully treated. Before procedure, cyst volumes were 21–676 cc (median: 94 cc). Post-procedure cyst volumes at last follow-up were 0-40 cc (median: 1 cc). The mean decrease in cyst volume was 95.92 ± 2.86 % in all patients (95.96 ± 3.26 % in Group A and 95.80 ± 6.20 % in Group B). There was no statistically significant difference between the volume reduction rates of Group A and Group B. Only one patient, in Group B, developed a major complication, an abscess. Hospitalization period was 1 day for all patients.ConclusionsFor patients with symptomatic simple hepatic cysts smaller than 500 cc in volume by using puncture, aspiration, injection, and reaspiration (PAIR) technique with only needle, single-session alcohol sclerotherapy of 10 min is a safe and effective procedure with high success rate.

  12. Long-Term Results of a Monocentric Series of Soldiers After Latarjet Procedure for Anterior Shoulder Instability. Implications for the Assessment of Soldiers' Medical Ability.

    Science.gov (United States)

    de l'Escalopier, Nicolas; Barbier, Olivier; Demoures, Thomas; Ollat, Didier; Versier, Gilbert

    2018-01-01

    Stabilizing surgery of the shoulder with a coracoid graft according to Latarjet is a recognized surgical treatment for anterior instability of the shoulder. This pathology frequently affects soldiers. Postoperatively, the potential risk of recurrence or of secondary shoulder arthritis can limit the practitioner in their ability assessment. The aim of this study is to analyze the long-term outcomes of this surgery in a military population, in order to assess the possible implications for French soldiers' medical ability. Twenty soldiers operated on the shoulder by Latarjet procedure by the same surgeon were retrospectively reviewed after more than 15 yr. All of them did regular physical activity for leisure or competitions. None had preoperative osteoarthritis injuries. The number of dislocation recurrences, the functional score, and the rate of radiographic osteoarthritis were assessed. After more than 16.3 yr (extremes: 15-24 yr), none displayed a dislocation recurrence. The average Rowe's score was 91.8 ± 9.9. The average subjective shoulder value was 89.2 ± 9.7. All patients had resumed sport. Three of them developed level 1 or 2 radiological signs of osteoarthritis according to Samilson. No level 3 or 4 osteoarthritis was found. Among all the patients, 14 still did regular physical activity. In view of our results and of those from the literature, the results of treatment for anterior shoulder instability with the Latarjet procedure are good, even very good in the long term. These data must be considered to favor this procedure for soldiers with shoulder instability and from a medico-administrative viewpoint for military patients in order to pursue their careers without any job restrictions. © Association of Military Surgeons of the United States 2017. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  13. Low rate of asymptomatic cerebral embolism and improved procedural efficiency with the novel pulmonary vein ablation catheter GOLD: results of the PRECISION GOLD trial.

    Science.gov (United States)

    De Greef, Yves; Dekker, Lukas; Boersma, Lucas; Murray, Stephen; Wieczorek, Marcus; Spitzer, Stefan G; Davidson, Neil; Furniss, Steve; Hocini, Mélèze; Geller, J Christoph; Csanádi, Zoltan

    2016-05-01

    This prospective, multicentre study (PRECISION GOLD) evaluated the incidence of asymptomatic cerebral embolism (ACE) after pulmonary vein isolation (PVI) using a new gold multi-electrode radiofrequency (RF) ablation catheter, pulmonary vein ablation catheter (PVAC) GOLD. Also, procedural efficiency of PVAC GOLD was compared with ERACE. The ERACE study demonstrated that a low incidence of ACE can be achieved with a platinum multi-electrode RF catheter (PVAC) combined with procedural manoeuvres to reduce emboli. A total of 51 patients with paroxysmal atrial fibrillation (AF) (age 57 ± 9 years, CHA2DS2-VASc score 1.4 ± 1.4) underwent AF ablation with PVAC GOLD. Continuous oral anticoagulation using vitamin K antagonists, submerged catheter introduction, and heparinization (ACT ≥ 350 s prior to ablation) were applied. Cerebral magnetic resonance imaging (MRI) scans were performed within 48 h before and 16-72 h post-ablation. Cognitive function assessed by the Mini-Mental State Exam at baseline and 30 days post-ablation. New post-procedural ACE occurred in only 1 of 48 patients (2.1%) and was not detectable on MRI after 30 days. The average number of RF applications per patient to achieve PVI was lower in PRECISION GOLD (20.3 ± 10.0) than in ERACE (28.8 ± 16.1; P = 0.001). Further, PVAC GOLD ablations resulted in significantly fewer low-power (GOLD in combination with established embolic lowering manoeuvres results in a low incidence of ACE. Pulmonary vein ablation catheter GOLD demonstrates improved biophysical efficiency compared with platinum PVAC. ClinicalTrials.gov NCT01767558. © The Author 2016. Published by Oxford University Press on behalf of the European Society of Cardiology.

  14. The Multipole Plasma Trap-PIC Modeling Results

    Science.gov (United States)

    Hicks, Nathaniel; Bowman, Amanda; Godden, Katarina

    2017-10-01

    A radio-frequency (RF) multipole structure is studied via particle-in-cell computer modeling, to assess the response of quasi-neutral plasma to the imposed RF fields. Several regimes, such as pair plasma, antimatter plasma, and conventional (ion-electron) plasma are considered. In the case of equal charge-to-mass ratio of plasma species, the effects of the multipole field are symmetric between positive and negative particles. In the case of a charge-to-mass disparity, the multipole RF parameters (frequency, voltage, structure size) may be chosen such that the light species (e.g. electrons) is strongly confined, while the heavy species (e.g. positive ions) does not respond to the RF field. In this case, the trapped negative space charge creates a potential well that then traps the positive species. 2D and 3D particle-in-cell simulations of this concept are presented, to assess plasma response and trapping dependences on multipole order, consequences of the formation of an RF plasma sheath, and the effects of an axial magnetic field. The scalings of trapped plasma parameters are explored in each of the mentioned regimes, to guide the design of prospective experiments investigating each. Supported by U.S. NSF/DOE Partnership in Basic Plasma Science and Engineering Grant PHY-1619615.

  15. Modeling Framework and Results to Inform Charging Infrastructure Investments

    Energy Technology Data Exchange (ETDEWEB)

    Melaina, Marc W [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Wood, Eric W [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

    2017-09-01

    The plug-in electric vehicle (PEV) market is experiencing rapid growth with dozens of battery electric (BEV) and plug-in hybrid electric (PHEV) models already available and billions of dollars being invested by automotive manufacturers in the PEV space. Electric range is increasing thanks to larger and more advanced batteries and significant infrastructure investments are being made to enable higher power fast charging. Costs are falling and PEVs are becoming more competitive with conventional vehicles. Moreover, new technologies such as connectivity and automation hold the promise of enhancing the value proposition of PEVs. This presentation outlines a suite of projects funded by the U.S. Department of Energy's Vehicle Technology Office to conduct assessments of the economic value and charging infrastructure requirements of the evolving PEV market. Individual assessments include national evaluations of PEV economic value (assuming 73M PEVs on the road in 2035), national analysis of charging infrastructure requirements (with community and corridor level resolution), and case studies of PEV ownership in Columbus, OH and Massachusetts.

  16. Results from the coupled Michigan MHD model and the Rice Convection Model

    Science.gov (United States)

    de Zeeuw, D.; Sazykin, S.; Wolf, R.; Gombosi, T.; Powell, K.

    A new high performance Rice Convection Model (RCM) has been coupled to the adaptive-grid Michigan MHD model (BATSRUS). This fully coupled code allows us to self-consistently simulate the physics in the inner and middle magnetosphere. A study will be presented of the basic characteristics of the inner and middle magnetosphere in the context of a single coupled-code run with steady inputs. The analysis will include region-2 currents, shielding of the inner magnetosphere, partial ring currents, pressure distribution, magnetic field inflation, and distribution of pV^gamma. The coupled-code simulation will be compared with results from RCM runs and algorithms.

  17. Two-loop renormalization in the standard model, part II. Renormalization procedures and computational techniques

    Energy Technology Data Exchange (ETDEWEB)

    Actis, S. [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany); Passarino, G. [Torino Univ. (Italy). Dipt. di Fisica Teorica; INFN, Sezione di Torino (Italy)

    2006-12-15

    In part I general aspects of the renormalization of a spontaneously broken gauge theory have been introduced. Here, in part II, two-loop renormalization is introduced and discussed within the context of the minimal Standard Model. Therefore, this paper deals with the transition between bare parameters and fields to renormalized ones. The full list of one- and two-loop counterterms is shown and it is proven that, by a suitable extension of the formalism already introduced at the one-loop level, two-point functions suffice in renormalizing the model. The problem of overlapping ultraviolet divergencies is analyzed and it is shown that all counterterms are local and of polynomial nature. The original program of 't Hooft and Veltman is at work. Finite parts are written in a way that allows for a fast and reliable numerical integration with all collinear logarithms extracted analytically. Finite renormalization, the transition between renormalized parameters and physical (pseudo-)observables, are discussed in part III where numerical results, e.g. for the complex poles of the unstable gauge bosons, are shown. An attempt is made to define the running of the electromagnetic coupling constant at the two-loop level. (orig.)

  18. Conceptual model and procedures to assimilate production technologies of bioenergetics of residual biomass

    International Nuclear Information System (INIS)

    Muto Lubota, David; González Suárez, Erenio; Hernández Pérez, Gilberto; Miño Valdés, Juan Esteban

    2016-01-01

    The present work expose the conceptual pattern for a process of assimilation of technologies with the purpose of creating obtaining capacities of bio energy with the objective of achieving an energy insurance of the recycle of Urban Solid Residuals (RSU) in the municipality of Cabinda, Angola. The conceptual pattern is novel because it considers the south-south collaboration, and it is supported by a general procedure of assimilation of the technologies that includes in one of its steps a specify procedure for the step concerning the insurance of the chain supply that contains as additional aspect, in a novel way, the determination of the initial’s investors capacities assisting to the demand of final products as well as to the readiness of the raw materials, based in the problems of uncertainty to the future changes. Finally conclusions are elaborated with projections for the future work. (author)

  19. ASSESSING GOING CONCERN ASSUMPTION BY USING RATING VALUATION MODELS BASED UPON ANALYTICAL PROCEDURES IN CASE OF FINANCIAL INVESTMENT COMPANIES

    OpenAIRE

    Tatiana Danescu; Ovidiu Spatacean; Paula Nistor; Andrea Cristina Danescu

    2010-01-01

    Designing and performing analytical procedures aimed to assess the rating of theFinancial Investment Companies are essential activities both in the phase of planning a financialaudit mission and in the phase of issuing conclusions regarding the suitability of using by themanagement and other persons responsible for governance of going concern, as the basis forpreparation and disclosure of financial statements. The paper aims to examine the usefulness ofrecognized models used in the practice o...

  20. Semantic Modeling of Administrative Procedures from a Spanish Regional Public Administration

    OpenAIRE

    Francisco José Hidalgo López; Jose Emilio Labra Gayo; Patricia Ordóñez de Pablos

    2018-01-01

    Over the past few years, Public Administrations have been providing systems for procedures and files electronic processing to ensure compliance with regulations and provide public services to citizens. Although each administration provides similar services to their citizens, these systems usually differ from the internal information management point of view since they usually come from different products and manufacturers. The common framework that regulations demand, and that Public Administ...

  1. Using the PLUM procedure of SPSS to fit unequal variance and generalized signal detection models.

    Science.gov (United States)

    DeCarlo, Lawrence T

    2003-02-01

    The recent addition of aprocedure in SPSS for the analysis of ordinal regression models offers a simple means for researchers to fit the unequal variance normal signal detection model and other extended signal detection models. The present article shows how to implement the analysis and how to interpret the SPSS output. Examples of fitting the unequal variance normal model and other generalized signal detection models are given. The approach offers a convenient means for applying signal detection theory to a variety of research.

  2. Stirling cryocooler test results and design model verification

    International Nuclear Information System (INIS)

    Shimko, M.A.; Stacy, W.D.; McCormick, J.A.

    1990-01-01

    This paper reports on progress in developing a long-life Stirling cycle cryocooler for space borne applications. It presents the results from tests on a preliminary breadboard version of the cryocooler used to demonstrate the feasibility of the technology and to validate the regenerator design code used in its development. This machine achieved a cold-end temperature of 65 K while carrying a 1/2 Watt cooling load. The basic machine is a double-acting, flexure-bearing, split Stirling design with linear electromagnetic drives for the expander and compressors. Flat metal diaphragms replace pistons for both sweeping and sealing the machine working volumes. In addition, the double-acting expander couples to a laminar-channel counterflow recuperative heat exchanger for regeneration. A PC compatible design code was developed for this design approach that calculates regenerator loss including heat transfer irreversibilities, pressure drop, and axial conduction in the regenerator walls

  3. Stress Resultant Based Elasto-Viscoplastic Thick Shell Model

    Directory of Open Access Journals (Sweden)

    Pawel Woelke

    2012-01-01

    Full Text Available The current paper presents enhancement introduced to the elasto-viscoplastic shell formulation, which serves as a theoretical base for the finite element code EPSA (Elasto-Plastic Shell Analysis [1–3]. The shell equations used in EPSA are modified to account for transverse shear deformation, which is important in the analysis of thick plates and shells, as well as composite laminates. Transverse shear forces calculated from transverse shear strains are introduced into a rate-dependent yield function, which is similar to Iliushin's yield surface expressed in terms of stress resultants and stress couples [12]. The hardening rule defined by Bieniek and Funaro [4], which allows for representation of the Bauschinger effect on a moment-curvature plane, was previously adopted in EPSA and is used here in the same form. Viscoplastic strain rates are calculated, taking into account the transverse shears. Only non-layered shells are considered in this work.

  4. Error statistics of hidden Markov model and hidden Boltzmann model results

    Directory of Open Access Journals (Sweden)

    Newberg Lee A

    2009-07-01

    Full Text Available Abstract Background Hidden Markov models and hidden Boltzmann models are employed in computational biology and a variety of other scientific fields for a variety of analyses of sequential data. Whether the associated algorithms are used to compute an actual probability or, more generally, an odds ratio or some other score, a frequent requirement is that the error statistics of a given score be known. What is the chance that random data would achieve that score or better? What is the chance that a real signal would achieve a given score threshold? Results Here we present a novel general approach to estimating these false positive and true positive rates that is significantly more efficient than are existing general approaches. We validate the technique via an implementation within the HMMER 3.0 package, which scans DNA or protein sequence databases for patterns of interest, using a profile-HMM. Conclusion The new approach is faster than general naïve sampling approaches, and more general than other current approaches. It provides an efficient mechanism by which to estimate error statistics for hidden Markov model and hidden Boltzmann model results.

  5. Surgical treatment of anterior instability in rugby union players: clinical and radiographic results of the Latarjet-Patte procedure with minimum 5-year follow-up.

    Science.gov (United States)

    Neyton, Lionel; Young, Allan; Dawidziak, Bérangère; Visona, Enrico; Hager, Jean-Philippe; Fournier, Yann; Walch, Gilles

    2012-12-01

    Anterior instability in rugby players is characterized by the common finding of a bony lesion, which has been identified as a potential cause of recurrence after soft-tissue reconstruction. The Latarjet-Patte procedure is effective in the treatment of recurrent anterior instability in collision sports such as rugby union. We retrospectively assessed 34 rugby players (37 shoulders) stabilized with the Latarjet-Patte procedure. The mean follow-up was 12 years. All patients underwent clinical and radiographic assessment preoperatively and at final follow-up. Functional evaluation was performed with the Walch-Duplay and Rowe scores. A visual analog scale score for the evaluation of pain and the subjective shoulder value were recorded. In addition, all patients completed a questionnaire regarding the return to playing rugby. No recurrence of either dislocation or subluxation occurred. Persistent apprehension on clinical examination was present in 5 patients (14%). A bony lesion of the glenoid was present in 73% and a Hill-Sachs lesion in 68%. Sixty-five percent of the patients returned to playing rugby; only 1 patient did not return to playing rugby because of his shoulder. The mean Walch-Duplay and Rowe scores were 86 and 93 points, respectively. The mean subjective shoulder value was 90%. Radiographic healing of the bone block was observed in 89% of cases. At final follow-up, 11 patients (30%) had minor arthritic changes, with no cases of moderate or severe arthritis. The Latarjet-Patte procedure provides a reliable method for stabilizing the shoulder, resulting in a return to playing rugby in a high number of cases without increasing the risk of long-term arthritic degradation. Copyright © 2012 Journal of Shoulder and Elbow Surgery Board of Trustees. Published by Mosby, Inc. All rights reserved.

  6. Modeling results for a linear simulator of a divertor

    Energy Technology Data Exchange (ETDEWEB)

    Hooper, E.B.; Brown, M.D.; Byers, J.A.; Casper, T.A.; Cohen, B.I.; Cohen, R.H.; Jackson, M.C.; Kaiser, T.B.; Molvik, A.W.; Nevins, W.M.; Nilson, D.G.; Pearlstein, L.D.; Rognlien, T.D.

    1993-06-23

    A divertor simulator, IDEAL, has been proposed by S. Cohen to study the difficult power-handling requirements of the tokamak program in general and the ITER program in particular. Projections of the power density in the ITER divertor reach {approximately} 1 Gw/m{sup 2} along the magnetic fieldlines and > 10 MW/m{sup 2} on a surface inclined at a shallow angle to the fieldlines. These power densities are substantially greater than can be handled reliably on the surface, so new techniques are required to reduce the power density to a reasonable level. Although the divertor physics must be demonstrated in tokamaks, a linear device could contribute to the development because of its flexibility, the easy access to the plasma and to tested components, and long pulse operation (essentially cw). However, a decision to build a simulator requires not just the recognition of its programmatic value, but also confidence that it can meet the required parameters at an affordable cost. Accordingly, as reported here, it was decided to examine the physics of the proposed device, including kinetic effects resulting from the intense heating required to reach the plasma parameters, and to conduct an independent cost estimate. The detailed role of the simulator in a divertor program is not explored in this report.

  7. Modeling results for a linear simulator of a divertor

    International Nuclear Information System (INIS)

    Hooper, E.B.; Brown, M.D.; Byers, J.A.; Casper, T.A.; Cohen, B.I.; Cohen, R.H.; Jackson, M.C.; Kaiser, T.B.; Molvik, A.W.; Nevins, W.M.; Nilson, D.G.; Pearlstein, L.D.; Rognlien, T.D.

    1993-01-01

    A divertor simulator, IDEAL, has been proposed by S. Cohen to study the difficult power-handling requirements of the tokamak program in general and the ITER program in particular. Projections of the power density in the ITER divertor reach ∼ 1 Gw/m 2 along the magnetic fieldlines and > 10 MW/m 2 on a surface inclined at a shallow angle to the fieldlines. These power densities are substantially greater than can be handled reliably on the surface, so new techniques are required to reduce the power density to a reasonable level. Although the divertor physics must be demonstrated in tokamaks, a linear device could contribute to the development because of its flexibility, the easy access to the plasma and to tested components, and long pulse operation (essentially cw). However, a decision to build a simulator requires not just the recognition of its programmatic value, but also confidence that it can meet the required parameters at an affordable cost. Accordingly, as reported here, it was decided to examine the physics of the proposed device, including kinetic effects resulting from the intense heating required to reach the plasma parameters, and to conduct an independent cost estimate. The detailed role of the simulator in a divertor program is not explored in this report

  8. MATLAB-implemented estimation procedure for model-based assessment of hepatic insulin degradation from standard intravenous glucose tolerance test data.

    Science.gov (United States)

    Di Nardo, Francesco; Mengoni, Michele; Morettini, Micaela

    2013-05-01

    Present study provides a novel MATLAB-based parameter estimation procedure for individual assessment of hepatic insulin degradation (HID) process from standard frequently-sampled intravenous glucose tolerance test (FSIGTT) data. Direct access to the source code, offered by MATLAB, enabled us to design an optimization procedure based on the alternating use of Gauss-Newton's and Levenberg-Marquardt's algorithms, which assures the full convergence of the process and the containment of computational time. Reliability was tested by direct comparison with the application, in eighteen non-diabetic subjects, of well-known kinetic analysis software package SAAM II, and by application on different data. Agreement between MATLAB and SAAM II was warranted by intraclass correlation coefficients ≥0.73; no significant differences between corresponding mean parameter estimates and prediction of HID rate; and consistent residual analysis. Moreover, MATLAB optimization procedure resulted in a significant 51% reduction of CV% for the worst-estimated parameter by SAAM II and in maintaining all model-parameter CV% MATLAB-based procedure was suggested as a suitable tool for the individual assessment of HID process. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  9. The Physical Models and Statistical Procedures Used in the RACER Monte Carlo Code

    Energy Technology Data Exchange (ETDEWEB)

    Sutton, T.M.; Brown, F.B.; Bischoff, F.G.; MacMillan, D.B.; Ellis, C.L.; Ward, J.T.; Ballinger, C.T.; Kelly, D.J.; Schindler, L.

    1999-07-01

    capability of performing iterated-source (criticality), multiplied-fixed-source, and fixed-source calculations. MCV uses a highly detailed continuous-energy (as opposed to multigroup) representation of neutron histories and cross section data. The spatial modeling is fully three-dimensional (3-D), and any geometrical region that can be described by quadric surfaces may be represented. The primary results are region-wise reaction rates, neutron production rates, slowing-down-densities, fluxes, leakages, and when appropriate the eigenvalue or multiplication factor. Region-wise nuclidic reaction rates are also computed, which may then be used by other modules in the system to determine time-dependent nuclide inventories so that RACER can perform depletion calculations. Furthermore, derived quantities such as ratios and sums of primary quantities and/or other derived quantities may also be calculated. MCV performs statistical analyses on output quantities, computing estimates of the 95% confidence intervals as well as indicators as to the reliability of these estimates. The remainder of this chapter provides an overview of the MCV algorithm. The following three chapters describe the MCV mathematical, physical, and statistical treatments in more detail. Specifically, Chapter 2 discusses topics related to tracking the histories including: geometry modeling, how histories are moved through the geometry, and variance reduction techniques related to the tracking process. Chapter 3 describes the nuclear data and physical models employed by MCV. Chapter 4 discusses the tallies, statistical analyses, and edits. Chapter 5 provides some guidance as to how to run the code, and Chapter 6 is a list of the code input options.

  10. A simple procedure to model water level fluctuations in partially inundated wetlands

    NARCIS (Netherlands)

    Spieksma, JFM; Schouwenaars, JM

    When modelling groundwater behaviour in wetlands, there are specific problems related to the presence of open water in small-sized mosaic patterns. A simple quasi two-dimensional model to predict water level fluctuations in partially inundated wetlands is presented. In this model, the ratio between

  11. Model Parameter Estimation Experiment (MOPEX): An overview of science strategy and major results from the second and third workshops

    Science.gov (United States)

    Duan, Q.; Schaake, J.; Andreassian, V.; Franks, S.; Goteti, G.; Gupta, H.V.; Gusev, Y.M.; Habets, F.; Hall, A.; Hay, L.; Hogue, T.; Huang, M.; Leavesley, G.; Liang, X.; Nasonova, O.N.; Noilhan, J.; Oudin, L.; Sorooshian, S.; Wagener, T.; Wood, E.F.

    2006-01-01

    The Model Parameter Estimation Experiment (MOPEX) is an international project aimed at developing enhanced techniques for the a priori estimation of parameters in hydrologic models and in land surface parameterization schemes of atmospheric models. The MOPEX science strategy involves three major steps: data preparation, a priori parameter estimation methodology development, and demonstration of parameter transferability. A comprehensive MOPEX database has been developed that contains historical hydrometeorological data and land surface characteristics data for many hydrologic basins in the United States (US) and in other countries. This database is being continuously expanded to include more basins in all parts of the world. A number of international MOPEX workshops have been convened to bring together interested hydrologists and land surface modelers from all over world to exchange knowledge and experience in developing a priori parameter estimation techniques. This paper describes the results from the second and third MOPEX workshops. The specific objective of these workshops is to examine the state of a priori parameter estimation techniques and how they can be potentially improved with observations from well-monitored hydrologic basins. Participants of the second and third MOPEX workshops were provided with data from 12 basins in the southeastern US and were asked to carry out a series of numerical experiments using a priori parameters as well as calibrated parameters developed for their respective hydrologic models. Different modeling groups carried out all the required experiments independently using eight different models, and the results from these models have been assembled for analysis in this paper. This paper presents an overview of the MOPEX experiment and its design. The main experimental results are analyzed. A key finding is that existing a priori parameter estimation procedures are problematic and need improvement. Significant improvement of these

  12. Trends in computational tools for biomagnetism: from procedural codes to intelligent scientific models.

    Science.gov (United States)

    Ioannides, A A

    1987-01-01

    The nature of the available computing tools strongly influences modern scientific investigations. The sources of well known problems associated with the use of procedural computer languages are traced and their consequences investigated. The likely impact of recent quantitative and qualitative advances in software and hardware is examined with emphasis on its relevance to the biomagnetic inverse problem. Gradual changes in the use of computers, some already employed in a recent study of a specific biomagnetic inverse problem, are outlined which take into account the large investment in conventional codes.

  13. Interaction between the written procedure and the technician: a fuzzy modeling approach

    International Nuclear Information System (INIS)

    More, Jesus Domech; Tansheit, Ricardo

    2005-01-01

    This paper deals with an application of fuzzy numbers to the interaction between the written procedure and the technician during inspection. The techniques based on fuzzy set theory are appropriate tools for the treatment of subjective and vague concepts that are inherent to system reliability. The application consists of an analysis through fuzzy probability and through a failure possibility concept, which is a subjective unreliability measure. This approach allows the use of natural language expressions of reliability estimation. It is shown which events (human actions) should be focused on during training and practice in order to improve the above mentioned interaction. (author)

  14. Discovering rare behaviours in stochastic differential equations using decision procedures: applications to a minimal cell cycle model.

    Science.gov (United States)

    Ghosh, Arup Kumar; Hussain, Faraz; Jha, Susmit; Langmead, Christopher J; Jha, Sumit Kumar

    2014-01-01

    Stochastic Differential Equation (SDE) models are used to describe the dynamics of complex systems with inherent randomness. The primary purpose of these models is to study rare but interesting or important behaviours, such as the formation of a tumour. Stochastic simulations are the most common means for estimating (or bounding) the probability of rare behaviours, but the cost of simulations increases with the rarity of events. To address this problem, we introduce a new algorithm specifically designed to quantify the likelihood of rare behaviours in SDE models. Our approach relies on temporal logics for specifying rare behaviours of interest, and on the ability of bit-vector decision procedures to reason exhaustively about fixed-precision arithmetic. We apply our algorithm to a minimal parameterised model of the cell cycle, and take Brownian noise into account while investigating the likelihood of irregularities in cell size and time between cell divisions.

  15. Is there value in retrospective 90-day bundle payment models for shoulder arthroplasty procedures?

    Science.gov (United States)

    Odum, Susan M; Hamid, Nady; Van Doren, Bryce A; Spector, Leo R

    2017-12-07

    The Centers for Medicare & Medicaid Services Bundled Payments for Care Improvement (BPCI) initiative was implemented as part of the Affordable Care Act. We implemented a retrospective payment model 2 for a 90-day total shoulder arthroplasty (TSA) episode to assess the value of TSA BPCI at our private practice. Expenditures and postacute event rates of 132 fee-for-service (FFS) patients who underwent a TSA operation between 2009 and 2012 were compared with 333 BPCI patients who had a TSA operation in 2015. The 90-day postacute events included an inpatient rehabilitation facility (IRF), skilled nursing facility (SNF), and home health (HH) admissions and readmissions. Expenditures were converted to 2016 dollars using the Consumer Price Index. Wilcoxon tests and multivariate generalized estimating equation were used to assess independent cost-drivers. The median FFS expenditure was $21,157 (interquartile range, $16,894-$30,748) compared with $17,894 (interquartile range, $15,796-$20,894) for BPCI (P spending, which resulted in decreased costs of performing TSA surgery. Copyright © 2017 Journal of Shoulder and Elbow Surgery Board of Trustees. Published by Elsevier Inc. All rights reserved.

  16. PV Performance Modeling Methods and Practices: Results from the 4th PV Performance Modeling Collaborative Workshop.

    Energy Technology Data Exchange (ETDEWEB)

    Stein, Joshua [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-03-01

    In 2014, the IEA PVPS Task 13 added the PVPMC as a formal activity to its technical work plan for 2014-2017. The goal of this activity is to expand the reach of the PVPMC to a broader international audience and help to reduce PV performance modeling uncertainties worldwide. One of the main deliverables of this activity is to host one or more PVPMC workshops outside the US to foster more international participation within this collaborative group. This report reviews the results of the first in a series of these joint IEA PVPS Task 13/PVPMC workshops. The 4th PV Performance Modeling Collaborative Workshop was held in Cologne, Germany at the headquarters of TÜV Rheinland on October 22-23, 2015.

  17. Analysis of short-term results of monsieur's tunica albuginea urethroplasty as a definitive procedure for pan-anterior urethral stricture

    Science.gov (United States)

    Sharma, Adittya K.; Ratkal, C. S.; Shivlingaiah, M.; Girish, G. N.; Sanjay, R. P.; Venkatesh, G. K.

    2013-01-01

    Context: Long anterior urethral strictures are fairly common in developing world and the treatment is equally challenging. Aim: To assess the results and efficacy of Monsieur's Tunica Albuginea Urethroplasty (TAU) for anterior urethral stricture. Settings and Design: We analyzed the results in 10 consecutive patients with pan-anterior urethral stricture, who underwent Monsieur's urethroplasty. Materials and Methods: The procedure involves mobilization of strictured urethra and laying it open with a dorsal slit. Edges of the slit-open urethra are sutured to edges of the urethral groove to the tunica of corporal bodies with catheter in situ. Results were assessed postoperatively 3, 6, 9 and 12 months. Patients were categorized as success and failure by comparative analysis of patient satisfaction along with urethroscopy, retrograde urethrogram, uroflowmetry. All patients were taken for post-operative urethroscopic analysis at 6 months to allow better understanding of both successful and failed cases. Results: Mean follow-up of 15.2 (11-19) months showed an 80% success rate. Mean uroflow rate showed Qmax 24.5 cc/sec with 8 cases showing no residual or recurrent stricture. Two cases failed and required intervention. Urethroscopic visualization of the reconstruction site showed wide, patent and distensible neourethra appearing epithelized over roof formed by tunica albuginea of the corpora cavernosa in successful cases. Conclusion: Monsieur's TAU is effective technique in treatment of anterior urethral stricture especially cases with unavailable buccal mucosa, with results fairly acceptable at the end of one year. PMID:24311899

  18. Longitudinal Data Analyses Using Linear Mixed Models in SPSS: Concepts, Procedures and Illustrations

    OpenAIRE

    Shek, Daniel T. L.; Ma, Cecilia M. S.

    2011-01-01

    Although different methods are available for the analyses of longitudinal data, analyses based on generalized linear models (GLM) are criticized as violating the assumption of independence of observations. Alternatively, linear mixed models (LMM) are commonly used to understand changes in human behavior over time. In this paper, the basic concepts surrounding LMM (or hierarchical linear models) are outlined. Although SPSS is a statistical analyses package commonly used by researchers, documen...

  19. A Novel Foam Contrast Agent Suitable for Fluoroscopic Interventional Procedure: Comparative Study of Physical Properties and Experimental Intervention in Animal Model

    Directory of Open Access Journals (Sweden)

    Jin Ho Hwang

    2015-01-01

    Full Text Available In fluoroscopic contrast study for interventional procedure, liquid contrast agent may be diluted in body fluid, losing its contrast effect. We developed a novel contrast agent of “foam state” to maintain contrast effect for enough time and performed a comparative study of physical properties and its usefulness in experimental intervention in animal model. The mean size of microbubble of foam contrast was 13.8±3.6 µm. The viscosity was 201.0±0.624 cP (centipoise and the specific gravity was 0.616. The foam decayed slowly and it had 97.5 minutes of half-life. In terms of the sustainability in a slow flow environment, foam contrast washed out much more slowly than a conventional contrast. In experimental colonic stent placement, foam contrast revealed significantly better results than conventional contrast in procedure time, total amount of contrast usage, and the number of injections (p<0.05. Our foam contrast has high viscosity and low specific gravity and maintains foam state for a sufficient time. Foam contrast with these properties was useful in experimental intervention in animal model. We anticipate that foam contrast may be applied to various kinds of interventional procedures.

  20. 3D radiation belt diffusion model results using new empirical models of whistler chorus and hiss

    Science.gov (United States)

    Cunningham, G.; Chen, Y.; Henderson, M. G.; Reeves, G. D.; Tu, W.

    2012-12-01

    3D diffusion codes model the energization, radial transport, and pitch angle scattering due to wave-particle interactions. Diffusion codes are powerful but are limited by the lack of knowledge of the spatial & temporal distribution of waves that drive the interactions for a specific event. We present results from the 3D DREAM model using diffusion coefficients driven by new, activity-dependent, statistical models of chorus and hiss waves. Most 3D codes parameterize the diffusion coefficients or wave amplitudes as functions of magnetic activity indices like Kp, AE, or Dst. These functional representations produce the average value of the wave intensities for a given level of magnetic activity; however, the variability of the wave population at a given activity level is lost with such a representation. Our 3D code makes use of the full sample distributions contained in a set of empirical wave databases (one database for each wave type, including plasmaspheric hiss, lower and upper hand chorus) that were recently produced by our team using CRRES and THEMIS observations. The wave databases store the full probability distribution of observed wave intensity binned by AE, MLT, MLAT and L*. In this presentation, we show results that make use of the wave intensity sample probability distributions for lower-band and upper-band chorus by sampling the distributions stochastically during a representative CRRES-era storm. The sampling of the wave intensity probability distributions produces a collection of possible evolutions of the phase space density, which quantifies the uncertainty in the model predictions caused by the uncertainty of the chorus wave amplitudes for a specific event. A significant issue is the determination of an appropriate model for the spatio-temporal correlations of the wave intensities, since the diffusion coefficients are computed as spatio-temporal averages of the waves over MLT, MLAT and L*. The spatiotemporal correlations cannot be inferred from the

  1. Accuracy of axial depth of cut in micromilling operations - Simplified procedure and uncertainty model

    DEFF Research Database (Denmark)

    Bissacco, Giuliano

    2005-01-01

    In order to maintain an optimum cutting speed, the reduction of mill diameters requires machine tools with high rotational speed capabilities. A solution to update existing machine tools is the use of high speed attached spindles. Major drawbacks of these attachments are the high thermal expansion...... and their rapid warming and cooling, which prevent the achievement of a steady state. Several other factors, independent on the tool-workpiece interaction, influence the machining accuracy. The cutting parameter most heavily affected is the axial depth of cut which is the most critical when using micro end mills......, due to the easy breakage particularly when milling on hard materials [1]. Typical values for the errors on the control of the axial depth of cut are in the order of 50 microns, while the aimed depth of cut can be as low as 5 microns. The author has developed a machining procedure for optimal control...

  2. 75 FR 52597 - Availability of Interim Procedures for Federal External Review and Model Notices Relating to...

    Science.gov (United States)

    2010-08-26

    ... Federal External Review and Model Notices Relating to Internal Claims and Appeals and External Review... external review process and model notices both for internal claims and appeals and for external review... standards for plans and issuers regarding both internal claims and appeals and external review. The...

  3. Examination of the potential problems resulting from the settling of U5 procedure (filtered venting of the containment) on French PWR'S

    International Nuclear Information System (INIS)

    L'Homme, A.; Serviere, G.

    1988-06-01

    A filtered venting system of the containment including a sand bed (U5 procedure) is now settled on french PWR's. In this paper, one reviews the problems which are raised, concerning either the efficiency of the system or the safety of the nuclear unit. Two types of situations are examined: design situations, for which the U5 procedure is not used, and hypothetical accidental situations, for which the U5 procedure could be used

  4. Short-term results of isolated phlebectomy with preservation of incompetent great saphenous vein (ASVAL procedure) in primary varicose veins disease.

    Science.gov (United States)

    Zolotukhin, Igor A; Seliverstov, Evgeny I; Zakharova, Elena A; Kirienko, Alexander I

    2017-10-01

    Objective To establish an effect of isolated phlebectomy in patients with incompetent great saphenous vein (Ambulatory Selective Varices Ablation under Local anesthesia (ASVAL) procedure) on the reflux and diameter of the trunk and to assess recurrence rate of varicose veins at one year. Material and methods We conducted a prospective study on patients with primary varicose veins and with C2 or C2,3 or C2,3,4 or C2,4 classes of chronic venous disease and great saphenous vein incompetence. The study included 67 patients (51 women and 16 men; 75 limbs in total). Age varied from 17 to 71 years; mean age was 46.8 years (SD 13.9). We recorded the presence or absence of reflux in the great saphenous vein with duplex ultrasound before and after surgery. The recurrence of varicose veins was evaluated at 12 months. All the patients underwent isolated phlebectomy with preservation of incompetent great saphenous vein (ASVAL procedure) under local anesthesia. Results At one year after removing of tributaries of the incompetent trunk, 66% of them were competent. Reflux persisted in 17% of great saphenous veins with reflux above mid-thigh and in 61% of trunks with reflux extended below the mid-thigh (p = 0.0004). The diameter of all the veins decreased significantly no matter reflux disappeared or not. Varicose veins reoccurred in 13.5% cases. In 6.5% of limbs with a reflux above the mid-thigh, the recurrence was registered at one year, while in the limbs with the reflux below the mid-thigh at a baseline, the recurrence rate was 25% (p = 0.036). Conclusion Isolated phlebectomy with a preservation of incompetent great saphenous vein leads to disappearance of reflux in a majority of cases and to significant decrease of vein diameter in all the cases. ASVAL procedure could be considered as a less aggressive and less expensive approach in selected cases. Clear indications for isolated phlebectomy need to be established.

  5. Establishing and validating luminiscence dating procedures for archaoelogical remains in the geochronology laboratory of the University of A Coruña: first results

    Directory of Open Access Journals (Sweden)

    Sanjurjo Sánchez, Jorge

    2008-12-01

    Full Text Available Thermoluminescence dating (TL of archaeological material is a technique about 50 years old, but it is not much used in Spain. Recent methodological advances have improved the accuracy and precision of the method. The unit of Geochronology of the University Geological Institute “Isidro Parga Pondal” University of A Coruña, has set up recently a Luminescence laboratory. In order to test analytical dating procedures, medieval tiles from an archaeological site next to the Hercules Tower (A Coruña have been dated. The stratigraphical column was previously dated by 14C, so a good chronological control is available. Samples were analysed using two different analytical procedures: a classical one using a multialiquot approach (AD-TL and a recent one using a single aliquot procedure (SAR-TL. Our results show that both methods yield comparable paleodoses, being the SAR-TL the one with smaller error.

    La datación mediante termoluminiscencia (TL de material arqueológico es una técnica con unos 50 años de antigüedad, aunque no muy empleada en España. Avances metodológicos recientes han permitido aumentar la exactitud y precisión del método. La Unidad de Geocronología del Instituto Universitario de Xeoloxía “Isidro Parga Pondal” de la Universidad de A Coruña cuenta en la actualidad con un Laboratorio de Luminiscencia. Para poner a punto los procedimientos analíticos de datación, se han datado tejas medievales de una excavación cercana a la Torre de Hércules (A Coruña en la que la columna estratigráfica fue datada por medio de 14C. Las muestras fueron sometidas a dos procedimientos existentes en la literatura: uno clásico (AD-TL y otro de reciente desarrollo (SAR-TL. Los resultados muestran concordancia entre ambos métodos e incluso mejoras considerables obtenidas con el SAR-TL.

  6. An initialization procedure for assimilating geostationary satellite data into numerical weather prediction models

    Science.gov (United States)

    Gal-Chen, T.; Schmidt, B.; Uccellini, L. W.

    1985-01-01

    An attempt was made to offset the limitations of GEO satellites for supplying timely initialization data for numerical weather prediction models (NWP). The NWP considered combined an isentropic representation of the free atmosphere with a sigma-coordinate model for the lower 200 mb. A flux form of the predictive equations described vertical transport interactions at the boundary of the two model domains, thereby accounting for the poor vertical temperature and wind field resolution of GEO satellite data. A variational analysis approach was employed to insert low resolution satellite-sensed temperature data at varying rates. The model vertical resolution was limited to that available from the satellite. Test simulations demonstrated that accuracy increases with the frequency of data updates, e.g., every 0.5-1 hr. The tests also showed that extensive cloud cover negates the capabilities of IR sensors and that microwave sensors will be needed for temperature estimations for 500-1000 mb levels.

  7. Creation of a continent urinary channel in adults with neurogenic bladder: long-term results with the Monti and Casale (Spiral Monti) procedures.

    Science.gov (United States)

    Hadley, David; Anderson, Kirk; Knopick, Christopher R; Shah, Ketul; Flynn, Brian J

    2014-05-01

    To describe our technique and long-term results with creation of a continent urinary channel in adults with neurogenic bladder (NGB) using a single piece of bowel. From 2004 to 2013, 26 adult patients underwent creation of a continent urinary channel by a single surgeon. A retrospective medical record review was performed noting the indications, technique, concomitant procedures, complications, and outcomes. Continence outcome, ease of catheterization, and need for further surgical interventions are reported. Twenty women and 6 men were identified with a mean age of 48 years (range, 25-80) and a follow-up of 64 months (range, 22-100). The mean body mass index (BMI) was 30.5 kg/m(2) (range, 20.1-50.2). All patients had benign bladder disease, including 22 (85%) with known neurologic disease and 4 with a devastated bladder outlet. Creation of a continent urinary channel was performed using the single Monti tube in 1, double Monti tube in 7, and the Casale (Spiral Monti) in 18. Mean hospital stay was 10.5 days (range, 5-37). The most common complication was recurrent urinary tract infection that occurred in 14 patients (54%). There were 5 (19%) bowel complications and 1 (4%) bladder perforation. The percentage of patients continuing to catheterize via the stoma with a BMI of 40 kg/m(2) was 89%, 50%, and 25%, respectively. The Monti and Casale procedures are effective in creating a long continent urinary channel for catheterization in the adult population with neurogenic bladder, regardless of BMI. However, despite an intact channel, stomal self-catheterization appears to be challenging in morbidly obese patients. Copyright © 2014 Elsevier Inc. All rights reserved.

  8. Awareness of radiation protection and dose levels of imaging procedures among medical students, radiography students, and radiology residents at an academic hospital: Results of a comprehensive survey

    Energy Technology Data Exchange (ETDEWEB)

    Faggioni, Lorenzo, E-mail: lfaggioni@sirm.org [Department of Diagnostic and Interventional Radiology, University of Pisa, Via Roma 67, 56100, Pisa (Italy); Paolicchi, Fabio [Department of Diagnostic and Interventional Radiology, University of Pisa, Via Roma 67, 56100, Pisa (Italy); Bastiani, Luca [Institute of Clinical Physiology, National Research Council, Via Moruzzi 1, 56124, Pisa (Italy); Guido, Davide [Unit of Biostatistics and Clinical Epidemiology, Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Via Forlanini 2, 27100, Pavia (Italy); Caramella, Davide [Department of Diagnostic and Interventional Radiology, University of Pisa, Via Roma 67, 56100, Pisa (Italy)

    2017-01-15

    Highlights: • Medical students tend to overstate their knowledge of radiation protection (RP). • Overall RP knowledge of young doctors and students is suboptimal. • RP teaching to undergraduates and postgraduates needs to be substantially improved. - Abstract: Purpose: To evaluate the awareness of radiation protection issues and the knowledge of dose levels of imaging procedures among medical students, radiology residents, and radiography students at an academic hospital. Material and methods: A total of 159 young doctors and students (including 60 radiology residents, 56 medical students, and 43 radiography students) were issued a questionnaire consisting of 16 multiple choice questions divided into three separated sections (i.e., demographic data, awareness about radiation protection issues, and knowledge about radiation dose levels of common radiological examinations). Results: Medical students claimed to have at least a good knowledge of radiation protection issues more frequently than radiology residents and radiography students (94.4% vs 55% and 35.7%, respectively; P < 0.05), with no cases of perceived excellent knowledge among radiography students. However, the actual knowledge of essential radiation protection topics such as regulations, patient and tissue susceptibility to radiation damage, professional radiation risk and dose optimisation, as well as of radiation doses delivered by common radiological procedures was significantly worse among medical students than radiology residents and radiography students (P < 0.05). Those latter significantly outperformed radiology residents as to knowledge of radiation protection issues (P < 0.01). Overall, less than 50% of survey respondents correctly answered all questions of the survey. Conclusions: Radiology residents, radiography students and medical students have a limited awareness about radiation protection, with a specific gap of knowledge concerning real radiation doses of daily radiological

  9. Registration procedure model for establishing a WFOE in the People's Republic of China

    OpenAIRE

    Polajžer, Boštjan; Markič, Mirko

    2013-01-01

    The purpose of this article is to present research outcomes and to compare the establishment of a limited liability company in the European setting and China, and, hence, design a uniform model that could serve to future investors as a framework or instructions for registering a fully foreign owned enterprise in China. A comparative theoretical study of company registration models in the selected European countries was used, on the basis of which we observed that registering a limited liabili...

  10. Three-dimensional patient-specific cardiac model for surgical planning in Nikaidoh procedure.

    Science.gov (United States)

    Valverde, Israel; Gomez, Gorka; Gonzalez, Antonio; Suarez-Mejias, Cristina; Adsuar, Alejandro; Coserria, Jose Felix; Uribe, Sergio; Gomez-Cia, Tomas; Hosseinpour, Amir Reza

    2015-04-01

    To explore the use of three-dimensional patient-specific cardiovascular models using rapid prototyping techniques (fused deposition modelling) to improve surgical planning in patients with complex congenital heart disease. Rapid prototyping techniques are used to print accurate three-dimensional replicas of patients' cardiovascular anatomy based on magnetic resonance images using computer-aided design systems. Models are printed using a translucent polylactic acid polymer. As a proof of concept, a model of the heart of a 1.5-year-old boy with transposition of the great arteries, ventricular septal defect and pulmonary stenosis was constructed to help planning the surgical correction. The cardiac model allowed the surgeon to evaluate the location and dimensions of the ventricular septal defect as well as its relationship with the aorta and pulmonary artery. Cardiovascular models constructed by rapid prototyping techniques are extremely helpful for planning corrective surgery in patients with complex congenital malformations. Therefore they may potentially reduce operative time and morbi-mortality.

  11. Accuracy of a computed tomography scanning procedure to manufacture digital models.

    Science.gov (United States)

    Darroudi, Amir M; Kuijpers-Jagtman, Anne Marie; Ongkosuwito, Edwin M; Suttorp, Christiaan Maarten; Bronkhorst, Ewald M; Breuning, K Hero

    2017-05-01

    Accurate articulation of the digital dental casts is crucial in orthodontic diagnosis and treatment planning. We aimed to determine the accuracy of manufacturing digital dental casts from computed tomography scanning of plaster casts regarding linear dimensions and interarch relationships and to test whether eventual differences in interarch relationships between plaster and digital casts would affect orthodontic diagnostics. Plaster casts with the wax bites of 2 patients were used to create digital dental casts with a computed tomography scanner. This was repeated 4 times with a 1-week interval. Linear distances were measured on plaster and digital models twice by 2 observers. Next, the 4 digital models of each patient were scored twice by 5 observers for interarch variables. Digital vs plaster measurements showed high Pearson correlation coefficients (>0.954), whereas the mean difference was small (<0.1 mm) and not significant. The interarch scorings, however, showed significant differences for all variables, except overjet for model 1. We found substantial interarch inaccuracies of the digital models. These inaccuracies are probably due to a lack of built-in "collision control" in the software and manual articulation of the digital models by a human operator. Copyright © 2017 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.

  12. Analysis of short-term results of monsieur′s tunica albuginea urethroplasty as a definitive procedure for pan-anterior urethral stricture

    Directory of Open Access Journals (Sweden)

    Adittya K Sharma

    2013-01-01

    Full Text Available Context: Long anterior urethral strictures are fairly common in developing world and the treatment is equally challenging. Aim: To assess the results and efficacy of Monsieur′s Tunica Albuginea Urethroplasty (TAU for anterior urethral stricture. Settings and Design: We analyzed the results in 10 consecutive patients with pan-anterior urethral stricture, who underwent Monsieur′s urethroplasty. Materials and Methods: The procedure involves mobilization of strictured urethra and laying it open with a dorsal slit. Edges of the slit-open urethra are sutured to edges of the urethral groove to the tunica of corporal bodies with catheter in situ. Results were assessed postoperatively 3, 6, 9 and 12 months. Patients were categorized as success and failure by comparative analysis of patient satisfaction along with urethroscopy, retrograde urethrogram, uroflowmetry. All patients were taken for post-operative urethroscopic analysis at 6 months to allow better understanding of both successful and failed cases. Results: Mean follow-up of 15.2 (11-19 months showed an 80% success rate. Mean uroflow rate showed Qmax 24.5 cc/sec with 8 cases showing no residual or recurrent stricture. Two cases failed and required intervention. Urethroscopic visualization of the reconstruction site showed wide, patent and distensible neourethra appearing epithelized over roof formed by tunica albuginea of the corpora cavernosa in successful cases. Conclusion: Monsieur′s TAU is effective technique in treatment of anterior urethral stricture especially cases with unavailable buccal mucosa, with results fairly acceptable at the end of one year.

  13. Theoretical modelling of experimental diagnostic procedures employed during pre-dose dosimetry of quartz

    International Nuclear Information System (INIS)

    Pagonis, V.; Chen, R.; Kitis, G.

    2006-01-01

    The pre-dose technique in thermoluminescence (TL) is used for dating archaeological ceramics and for accident dosimetry. During routine applications of this technique, the sensitisation of the quartz samples is measured as a function of the annealing temperature, yielding the so-called thermal activation characteristic (TAC). The measurement of multiple TACs and the study of the effect of UV-radiation on the TL sensitivity of quartz are important analytical and diagnostic tools. In this paper, it is shown that a modified Zimmerman model for quartz can successfully model the experimental steps undertaken during a measurement of multiple TACs. (authors)

  14. Peptidomic profiling of secreted products from pancreatic islet culture results in a higher yield of full-length peptide hormones than found using cell lysis procedures.

    Science.gov (United States)

    Taylor, Steven W; Nikoulina, Svetlana E; Andon, Nancy L; Lowe, Carolyn

    2013-08-02

    Peptide Hormone Acquisition through Smart Sampling Technique-Mass Spectrometry (PHASST-MS) is a peptidomics platform that employs high resolution liquid chromatography-mass spectrometry (LC-MS) techniques to identify peptide hormones secreted from in vitro or ex vivo cultures enriched in endocrine cells. Application of the methodology to the study of murine pancreatic islets has permitted evaluation of the strengths and weaknesses of the approach, as well as comparison of our results with published islet studies that employed traditional cellular lysis procedures. We found that, while our PHASST-MS approach identified fewer peptides in total, we had greater representation of intact peptide hormones. The technique was further refined to improve coverage of hydrophilic as well as hydrophobic peptides and subsequently applied to human pancreatic islet cultures derived from normal donors or donors with type 2 diabetes. Interestingly, in addition to the expected islet hormones, we identified alpha-cell-derived bioactive GLP-1, consistent with recent reports of paracrine effects of this hormone on beta-cell function. We also identified many novel peptides derived from neurohormonal precursors and proteins related to the cell secretory system. Taken together, these results suggest the PHASST-MS strategy of focusing on cellular secreted products rather than the total tissue peptidome may improve the probability of discovering novel bioactive peptides and also has the potential to offer important new insights into the secretion and function of known hormones.

  15. A general procedure to model and to analyze pipelines with real defects caused by corrosion measured in situ

    Energy Technology Data Exchange (ETDEWEB)

    Ferreira, Adriano D.M.; Souza, Antonio H.T. de; Willmersdorf, Ramiro B.; Lira, Paulo R.M. [Universidade Federal de Pernambuco (UFPE), Recife, PE (Brazil). Dept. de Engenharia Mecanica; Silvana, M.B. Afonso; Motta, Renato S. [Universidade Federal de Pernambuco (UFPE), Recife, PE (Brazil). Dept. de Engenharia Civil; Andrade, Edmundo Q. de [PETROBRAS S.A., Rio de Janeiro, RJ (Brazil). Centro de Pesquisas

    2009-07-01

    The main purpose of this work is to present an automatic procedure to generate a geometric model and FE meshes from data provided by some field inspection. From the data provided a smooth geometry representation in the corroded area of the pipeline is generated. This generation is coupled with surface tools provided by MSC.Patran Soft-ware, pre and post-processing, program. To accomplish the generation of the whole model, discretization rules were coded for the corroded area and for the interfaces necessary to fulfill the discretization of the whole model. In this work, the module that automatized the generation of computer models of identified defects with irregular geometry is described in detail. These modules were implemented with functions written in the programming language PCL (Patran Command Language) and added to the program PIPEFLAW (Cabral, 2007) developed by the group PADMEC (High Perform Computing on Computational Mechanics) from UFPE. The program has a friendly and customized graphical interface which allows the user to provide the main parameters of the pipe and defect. A structural non-linear analysis was performed for some models to obtain the internal pressure that would cause rupture of the model, representing the mechanical failure of the pipeline. For the purpose of numerical analysis the commercial finite element program ANSYS was used, which were being managed by scripts written in Phyton. (author)

  16. Combining Decision Diagrams and SAT Procedures for Efficient Symbolic Model Checking

    DEFF Research Database (Denmark)

    Williams, Poul Frederick; Biere, Armin; Clarke, Edmund M.

    2000-01-01

    In this paper we show how to do symbolic model checking using Boolean Expression Diagrams (BEDs), a non-canonical representation for Boolean formulas, instead of Binary Decision Diagrams (BDDs), the traditionally used canonical representation. The method is based on standard fixed point algorithms...

  17. The Chain-Link Fence Model: A Framework for Creating Security Procedures

    Science.gov (United States)

    Houghton, Robert F.

    2013-01-01

    A long standing problem in information technology security is how to help reduce the security footprint. Many specific proposals exist to address specific problems in information technology security. Most information technology solutions need to be repeatable throughout the course of an information systems lifecycle. The Chain-Link Fence Model is…

  18. Integrating semantics and procedural generation: key enabling factors for declarative modeling of virtual worlds

    NARCIS (Netherlands)

    Bidarra, R.; Kraker, K.J. de; Smelik, R.M.; Tutenel, T.

    2010-01-01

    Manual content creation for virtual worlds can no longer satisfy the increasing demand arising from areas as entertainment and serious games, simulations, movies, etc. Furthermore, currently deployed modeling tools basically do not scale up: while they become more and more specialized and complex,

  19. Fused Deposition Modeling 3D Printing for (Bio)analytical Device Fabrication : Procedures, Materials, and Applications

    NARCIS (Netherlands)

    Salentijn, Gert Ij; Oomen, Pieter E; Grajewski, Maciej; Verpoorte, Elisabeth

    2017-01-01

    In this work, the use of fused deposition modeling (FDM) in a (bio)analytical/lab-on-a-chip research laboratory is described. First, the specifications of this 3D printing method that are important for the fabrication of (micro)devices were characterized for a benchtop FDM 3D printer. These include

  20. Enzyme Replacement Therapy and/or Hematopoietic Stem Cell Transplantation at diagnosis in patients with Mucopolysaccharidosis type I: results of a European consensus procedure

    LENUS (Irish Health Repository)

    de Ru, Minke H

    2011-08-10

    Abstract Background Mucopolysaccharidosis type I (MPS I) is a lysosomal storage disorder that results in the accumulation of glycosaminoglycans causing progressive multi-organ dysfunction. Its clinical spectrum is very broad and varies from the severe Hurler phenotype (MPS I-H) which is characterized by early and progressive central nervous system (CNS) involvement to the attenuated Scheie phenotype (MPS I-S) with no CNS involvement. Indication, optimal timing, safety and efficacy of the two available treatment options for MPS I, enzyme replacement therapy (ERT) and hematopoietic stem cell transplantation (HSCT), are subject to continuing debate. A European consensus procedure was organized to reach consensus about the use of these two treatment strategies. Methods A panel of specialists, including 8 specialists for metabolic disorders and 7 bone marrow transplant physicians, all with acknowledged expertise in MPS I, participated in a modified Delphi process to develop consensus-based statements on MPS I treatment. Fifteen MPS I case histories were used to initiate the discussion and to anchor decisions around either treatment mode. Before and at the meeting all experts gave their opinion on the cases (YES\\/NO transplantation) and reasons for their decisions were collected. A set of draft statements on MPS I treatment options composed by a planning committee were discussed and revised during the meeting until full consensus. Results Full consensus was reached on several important issues, including the following: 1) The preferred treatment for patients with MPS I-H diagnosed before age 2.5 yrs is HSCT; 2) In individual patients with an intermediate phenotype HSCT may be considered if there is a suitable donor. However, there are no data on efficacy of HSCT in patients with this phenotype; 3) All MPS I patients including those who have not been transplanted or whose graft has failed may benefit significantly from ERT; 4) ERT should be started at diagnosis and may be