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Sample records for model types saphire

  1. SAPHIRE models and software for ASP evaluations

    Energy Technology Data Exchange (ETDEWEB)

    Sattison, M.B.; Schroeder, J.A.; Russell, K.D. [Idaho National Engineering Lab., Idaho Falls, ID (United States)] [and others

    1995-04-01

    The Idaho National Engineering Laboratory (INEL) over the past year has created 75 plant-specific Accident Sequence Precursor (ASP) models using the SAPHIRE suite of PRA codes. Along with the new models, the INEL has also developed a new module for SAPHIRE which is tailored specifically to the unique needs of conditional core damage probability (CCDP) evaluations. These models and software will be the next generation of risk tools for the evaluation of accident precursors by both NRR and AEOD. This paper presents an overview of the models and software. Key characteristics include: (1) classification of the plant models according to plant response with a unique set of event trees for each plant class, (2) plant-specific fault trees using supercomponents, (3) generation and retention of all system and sequence cutsets, (4) full flexibility in modifying logic, regenerating cutsets, and requantifying results, and (5) user interface for streamlined evaluation of ASP events.

  2. Saphire models and software for ASP evaluations

    Energy Technology Data Exchange (ETDEWEB)

    Sattison, M.B. [Idaho National Engineering Lab., Idaho Falls, ID (United States)

    1997-02-01

    The Idaho National Engineering Laboratory (INEL) over the three years has created 75 plant-specific Accident Sequence Precursor (ASP) models using the SAPHIRE suite of PRA codes. Along with the new models, the INEL has also developed a new module for SAPHIRE which is tailored specifically to the unique needs of ASP evaluations. These models and software will be the next generation of risk tools for the evaluation of accident precursors by both the U.S. Nuclear Regulatory Commission`s (NRC`s) Office of Nuclear Reactor Regulation (NRR) and the Office for Analysis and Evaluation of Operational Data (AEOD). This paper presents an overview of the models and software. Key characteristics include: (1) classification of the plant models according to plant response with a unique set of event trees for each plant class, (2) plant-specific fault trees using supercomponents, (3) generation and retention of all system and sequence cutsets, (4) full flexibility in modifying logic, regenerating cutsets, and requantifying results, and (5) user interface for streamlined evaluation of ASP events. Future plans for the ASP models is also presented.

  3. 75 FR 33162 - Airworthiness Directives; Microturbo Saphir 20 Model 095 Auxiliary Power Units (APUs)

    Science.gov (United States)

    2010-06-11

    ...-21-AD; Amendment 39-16332; AD 2010-13-01] RIN 2120-AA64 Airworthiness Directives; Microturbo Saphir..., of the SAPHIR 20 Model 095 APU is a life-limited part. Microturbo had determined through ``fleet...-015-03, of the SAPHIR 20 Model 095 APU is a life-limited part. Microturbo had determined...

  4. Methods improvements incorporated into the SAPHIRE ASP models

    Energy Technology Data Exchange (ETDEWEB)

    Sattison, M.B.; Blackman, H.S.; Novack, S.D. [Idaho National Engineering Lab., Idaho Falls, ID (United States)] [and others

    1995-04-01

    The Office for Analysis and Evaluation of Operational Data (AEOD) has sought the assistance of the Idaho National Engineering Laboratory (INEL) to make some significant enhancements to the SAPHIRE-based Accident Sequence Precursor (ASP) models recently developed by the INEL. The challenge of this project is to provide the features of a full-scale PRA within the framework of the simplified ASP models. Some of these features include: (1) uncertainty analysis addressing the standard PRA uncertainties and the uncertainties unique to the ASP models and methods, (2) incorporation and proper quantification of individual human actions and the interaction among human actions, (3) enhanced treatment of common cause failures, and (4) extension of the ASP models to more closely mimic full-scale PRAs (inclusion of more initiators, explicitly modeling support system failures, etc.). This paper provides an overview of the methods being used to make the above improvements.

  5. SAPHIRE 8 New Features and Capabilities

    Energy Technology Data Exchange (ETDEWEB)

    Curtis Smith

    2008-08-01

    The Systems Analysis Programs for Hands-on Integrated Reliability Evaluations (SAPHIRE) software performs probabilistic risk assessment (PRA) calculations. SAPHIRE is used in support of NRC’s risk-informed programs such as the Accident Sequence Precursor (ASP) program, Management Directive 8.3, “NRC Incident Investigation Program,” or the Significance Determination Process (SDP). It is also used to develop and run the Standardized Plant Analysis Risk (SPAR) models. SAPHIRE Version 8 is a new version of the software with an improved interface and capabilities to support risk-informed programs. SAPHIRE Version 8 is designed to easily handle larger and more complex models. Applications of previous SAPHIRE versions indicated the need to build and solve models with a large number of sequences. Risk assessments that include endstate evaluations for core damage frequency and large, early release frequency evaluations have greatly increased the number of sequences required. In addition, the complexity of the models has increased since risk assessments evaluate both potential internal and external events, as well as different plant operational states. Special features of SAPHIRE 8 help create and run integrated models which may be composed of different model types. SAPHIRE 8 includes features and capabilities that are new or improved over the current Version 7 to address the new requirements for risk-informed programs and SPAR models. These include: • Improved User Interfaces • Model development • Methods • General Support Features

  6. All-sky radiance simulation of Megha-Tropiques SAPHIR microwave sensor using multiple scattering radiative transfer model for data assimilation applications

    Indian Academy of Sciences (India)

    A Madhulatha; John P George; E N Rajagopal

    2017-03-01

    Incorporation of cloud- and precipitation-affected radiances from microwave satellite sensors in data assimilation system has a great potential in improving the accuracy of numerical model forecasts over the regions of high impact weather. By employing the multiple scattering radiative transfer model RTTOVSCATT,all-sky radiance (clear sky and cloudy sky) simulation has been performed for six channel microwave SAPHIR (Sounder for Atmospheric Profiling of Humidity in the Inter-tropics by Radiometry) sensors of Megha-Tropiques (MT) satellite. To investigate the importance of cloud-affected radiance data in severe weather conditions, all-sky radiance simulation is carried out for the severe cyclonic storm ‘Hudhud’ formed over Bay of Bengal. Hydrometeors from NCMRWF unified model (NCUM) forecasts are used as input to the RTTOV model to simulate cloud-affected SAPHIR radiances. Horizontal and vertical distribution of all-sky simulated radiances agrees reasonably well with the SAPHIR observed radiancesover cloudy regions during different stages of cyclone development. Simulated brightness temperatures of six SAPHIR channels indicate that the three dimensional humidity structure of tropical cyclone is well represented in all-sky computations. Improved correlation and reduced bias and root mean squareerror against SAPHIR observations are apparent. Probability distribution functions reveal that all-sky simulations are able to produce the cloud-affected lower brightness temperatures associated with cloudy regions. The density scatter plots infer that all-sky radiances are more consistent with observed radiances.Correlation between different types of hydrometeors and simulated brightness temperatures at respective atmospheric levels highlights the significance of inclusion of scattering effects from different hydrometeors in simulating the cloud-affected radiances in all-sky simulations. The results are promisingand suggest that the inclusion of multiple scattering

  7. All-sky radiance simulation of Megha-Tropiques SAPHIR microwave sensor using multiple scattering radiative transfer model for data assimilation applications

    Science.gov (United States)

    Madhulatha, A.; George, John P.; Rajagopal, E. N.

    2017-03-01

    Incorporation of cloud- and precipitation-affected radiances from microwave satellite sensors in data assimilation system has a great potential in improving the accuracy of numerical model forecasts over the regions of high impact weather. By employing the multiple scattering radiative transfer model RTTOV-SCATT, all-sky radiance (clear sky and cloudy sky) simulation has been performed for six channel microwave SAPHIR (Sounder for Atmospheric Profiling of Humidity in the Inter-tropics by Radiometry) sensors of Megha-Tropiques (MT) satellite. To investigate the importance of cloud-affected radiance data in severe weather conditions, all-sky radiance simulation is carried out for the severe cyclonic storm `Hudhud' formed over Bay of Bengal. Hydrometeors from NCMRWF unified model (NCUM) forecasts are used as input to the RTTOV model to simulate cloud-affected SAPHIR radiances. Horizontal and vertical distribution of all-sky simulated radiances agrees reasonably well with the SAPHIR observed radiances over cloudy regions during different stages of cyclone development. Simulated brightness temperatures of six SAPHIR channels indicate that the three dimensional humidity structure of tropical cyclone is well represented in all-sky computations. Improved correlation and reduced bias and root mean square error against SAPHIR observations are apparent. Probability distribution functions reveal that all-sky simulations are able to produce the cloud-affected lower brightness temperatures associated with cloudy regions. The density scatter plots infer that all-sky radiances are more consistent with observed radiances. Correlation between different types of hydrometeors and simulated brightness temperatures at respective atmospheric levels highlights the significance of inclusion of scattering effects from different hydrometeors in simulating the cloud-affected radiances in all-sky simulations. The results are promising and suggest that the inclusion of multiple scattering

  8. SAPHIRE 8 Volume 1 - Overview and Summary

    Energy Technology Data Exchange (ETDEWEB)

    C. L. Smith; S. T. Wood

    2011-03-01

    The Systems Analysis Programs for Hands-on Integrated Reliability Evaluations (SAPHIRE) is a software application developed for performing a complete probabilistic risk assessment (PRA) using a personal computer (PC) running the Microsoft Windows operating system. SAPHIRE Version 8 is funded by the U.S. Nuclear Regulatory Commission (NRC) and developed by the Idaho National Laboratory (INL). INL's primary role in this project is that of software developer and tester. However, INL also plays an important role in technology transfer by interfacing and supporting SAPHIRE users, who constitute a wide range of PRA practitioners from the NRC, national laboratories, the private sector, and foreign countries. SAPHIRE can be used to model a complex system’s response to initiating events and quantify associated consequential outcome frequencies. Specifically, for nuclear power plant applications, SAPHIRE 8 can identify important contributors to core damage (Level 1 PRA) and containment failure during a severe accident which leads to releases (Level 2 PRA). It can be used for a PRA where the reactor is at full power, low power, or at shutdown conditions. Furthermore, it can be used to analyze both internal and external initiating events and has special features for managing models such as flooding and fire. It can also be used in a limited manner to quantify risk in terms of release consequences to the public and environment (Level 3 PRA). In SAPHIRE 8, the act of creating a model has been separated from the analysis of that model in order to improve the quality of both the model (e.g., by avoiding inadvertent changes) and the analysis. Consequently, in SAPHIRE 8, the analysis of models is performed by using what are called Workspaces. Currently, there are Workspaces for three types of analyses: (1) the NRC’s Accident Sequence Precursor program, where the workspace is called “Events and Condition Assessment (ECA);” (2) the NRC’s Significance Determination

  9. SAPHIRE 8 Software Project Plan

    Energy Technology Data Exchange (ETDEWEB)

    Curtis L.Smith; Ted S. Wood

    2010-03-01

    This project is being conducted at the request of the DOE and the NRC. The INL has been requested by the NRC to improve and maintain the Systems Analysis Programs for Hands-on Integrated Reliability Evaluation (SAPHIRE) tool set concurrent with the changing needs of the user community as well as staying current with new technologies. Successful completion will be upon NRC approved release of all software and accompanying documentation in a timely fashion. This project will enhance the SAPHIRE tool set for the user community (NRC, Nuclear Power Plant operations, Probabilistic Risk Analysis (PRA) model developers) by providing improved Common Cause Failure (CCF), External Events, Level 2, and Significance Determination Process (SDP) analysis capabilities. The SAPHIRE development team at the Idaho National Laboratory is responsible for successful completion of this project. The project is under the supervision of Curtis L. Smith, PhD, Technical Lead for the SAPHIRE application. All current capabilities from SAPHIRE version 7 will be maintained in SAPHIRE 8. The following additional capabilities will be incorporated: • Incorporation of SPAR models for the SDP interface. • Improved quality assurance activities for PRA calculations of SAPHIRE Version 8. • Continue the current activities for code maintenance, documentation, and user support for the code.

  10. SAPHIR: a physiome core model of body fluid homeostasis and blood pressure regulation.

    Science.gov (United States)

    Thomas, S Randall; Baconnier, Pierre; Fontecave, Julie; Françoise, Jean-Pierre; Guillaud, François; Hannaert, Patrick; Hernández, Alfredo; Le Rolle, Virginie; Mazière, Pierre; Tahi, Fariza; White, Ronald J

    2008-09-13

    We present the current state of the development of the SAPHIR project (a Systems Approach for PHysiological Integration of Renal, cardiac and respiratory function). The aim is to provide an open-source multi-resolution modelling environment that will permit, at a practical level, a plug-and-play construction of integrated systems models using lumped-parameter components at the organ/tissue level while also allowing focus on cellular- or molecular-level detailed sub-models embedded in the larger core model. Thus, an in silico exploration of gene-to-organ-to-organism scenarios will be possible, while keeping computation time manageable. As a first prototype implementation in this environment, we describe a core model of human physiology targeting the short- and long-term regulation of blood pressure, body fluids and homeostasis of the major solutes. In tandem with the development of the core models, the project involves database implementation and ontology development.

  11. Coupling CFAST fire modeling and SAPHIRE probabilistic assessment software for internal fire safety evaluation of a typical TRIGA research reactor

    Energy Technology Data Exchange (ETDEWEB)

    Safaei Arshi, Saiedeh [School of Engineering, Shiraz University, 71348-51154 Shiraz (Iran, Islamic Republic of); Nematollahi, Mohammadreza, E-mail: nema@shirazu.ac.i [School of Engineering, Shiraz University, 71348-51154 Shiraz (Iran, Islamic Republic of); Safety Research Center of Shiraz University, 71348-51154 Shiraz (Iran, Islamic Republic of); Sepanloo, Kamran [Safety Research Center of Shiraz University, 71348-51154 Shiraz (Iran, Islamic Republic of)

    2010-03-15

    Due to the significant threat of internal fires for the safety operation of nuclear reactors, presumed fire scenarios with potential hazards for loss of typical research reactor safety functions are analyzed by coupling CFAST fire modeling and SAPHIRE probabilistic assessment software. The investigations show that fire hazards associated with electrical cable insulation, lubricating oils, diesel, electrical equipment and carbon filters may lead to unsafe situations called core damage states. Using system-specific event trees, the occurrence frequency of core damage states after the occurrence of each possible fire scenario in critical fire compartments is evaluated. Probability that the fire ignited in the given fire compartment will burn long enough to cause the extent of damage defined by each fire scenario is calculated by means of detection-suppression event tree. As a part of detection-suppression event trees quantification, and also for generating the necessary input data for evaluating the frequency of core damage states by SAPHIRE 7.0 software, CFAST fire modeling software is applied. The results provide a probabilistic measure of the quality of existing fire protection systems in order to maintain the reactor at a reasonable safety level.

  12. SAPHIRE 8 Volume 7 - Data Loading

    Energy Technology Data Exchange (ETDEWEB)

    K. J. Kvarfordt; S. T. Wood; C. L. Smith; S. R. Prescott

    2011-03-01

    The Systems Analysis Programs for Hands-on Integrated Reliability Evaluations (SAPHIRE) is a software application developed for performing a complete probabilistic risk assessment (PRA) using a personal computer. SAPHIRE Version 8 is funded by the U.S. Nuclear Regulatory Commission and developed by the Idaho National Laboratory. This report is intended to assist the user to enter PRA data into the SAPHIRE program using the built-in MAR-D ASCII-text file data transfer process. Towards this end, a small sample database is constructed and utilized for demonstration. Where applicable, the discussion includes how the data processes for loading the sample database relate to the actual processes used to load a larger PRA models. The procedures described herein were developed for use with SAPHIRE Version 8. The guidance specified in this document will allow a user to have sufficient knowledge to both understand the data format used by SAPHIRE and to carry out the transfer of data between different PRA projects.

  13. SAPHIR - a multi-scale, multi-resolution modeling environment targeting blood pressure regulation and fluid homeostasis.

    Science.gov (United States)

    Thomas, S; Abdulhay, Enas; Baconnier, Pierre; Fontecave, Julie; Francoise, Jean-Pierre; Guillaud, Francois; Hannaert, Patrick; Hernandez, Alfredo; Le Rolle, Virginie; Maziere, Pierre; Tahi, Fariza; Zehraoui, Farida

    2007-01-01

    We present progress on a comprehensive, modular, interactive modeling environment centered on overall regulation of blood pressure and body fluid homeostasis. We call the project SAPHIR, for "a Systems Approach for PHysiological Integration of Renal, cardiac, and respiratory functions". The project uses state-of-the-art multi-scale simulation methods. The basic core model will give succinct input-output (reduced-dimension) descriptions of all relevant organ systems and regulatory processes, and it will be modular, multi-resolution, and extensible, in the sense that detailed submodules of any process(es) can be "plugged-in" to the basic model in order to explore, eg. system-level implications of local perturbations. The goal is to keep the basic core model compact enough to insure fast execution time (in view of eventual use in the clinic) and yet to allow elaborate detailed modules of target tissues or organs in order to focus on the problem area while maintaining the system-level regulatory compensations.

  14. SAPHIR, how it ended

    Energy Technology Data Exchange (ETDEWEB)

    Brogli, R.; Hammer, J.; Wiezel, L.; Christen, R.; Heyck, H.; Lehmann, E. [Paul Scherrer Inst. (PSI), Villigen (Switzerland)

    1995-10-01

    On May 16th, 1994, PSI decided to discontinue its efforts to retrofit the SAPHIR reactor for operation at 10 MW. This decision was made because the effort and time for the retrofit work in progress had proven to be more complex than was anticipated. In view of the start-up of the new spallation-neutron source SINQ in 1996, the useful operating time between the eventual restart of SAPHIR and the start-up of SINQ became less than two years, which was regarded by PSI as too short a period to warrant the large retrofit effort. Following the decision of PSI not to re-use SAPHIR as a neutron source, several options for the further utilization of the facility were open. However, none of them appeared promising in comparison with other possibilities; it was therefore decided that SAPHIR should be decommissioned. A concerted effort was initiated to consolidate the nuclear and conventional safety for the post-operational period. (author) 3 figs., 3 tab.

  15. Assimilation of SAPHIR radiance: impact on hyperspectral radiances in 4D-VAR

    Science.gov (United States)

    Indira Rani, S.; Doherty, Amy; Atkinson, Nigel; Bell, William; Newman, Stuart; Renshaw, Richard; George, John P.; Rajagopal, E. N.

    2016-04-01

    Assimilation of a new observation dataset in an NWP system may affect the quality of an existing observation data set against the model background (short forecast), which in-turn influence the use of an existing observation in the NWP system. Effect of the use of one data set on the use of another data set can be quantified as positive, negative or neutral. Impact of the addition of new dataset is defined as positive if the number of assimilated observations of an existing type of observation increases, and bias and standard deviation decreases compared to the control (without the new dataset) experiment. Recently a new dataset, Megha Tropiques SAPHIR radiances, which provides atmospheric humidity information, is added in the Unified Model 4D-VAR assimilation system. In this paper we discuss the impact of SAPHIR on the assimilation of hyper-spectral radiances like AIRS, IASI and CrIS. Though SAPHIR is a Microwave instrument, its impact can be clearly seen in the use of hyper-spectral radiances in the 4D-VAR data assimilation systems in addition to other Microwave and InfraRed observation. SAPHIR assimilation decreased the standard deviation of the spectral channels of wave number from 650 -1600 cm-1 in all the three hyperspectral radiances. Similar impact on the hyperspectral radiances can be seen due to the assimilation of other Microwave radiances like from AMSR2 and SSMIS Imager.

  16. Can SAPHIR Instrument Onboard MEGHATROPIQUES Retrieve Hydrometeors and Rainfall Characteristics ?

    Science.gov (United States)

    Goyal, J. M.; Srinivasan, J.; Satheesh, S. K.

    2014-12-01

    MEGHATROPIQUES (MT) is an Indo-French satellite launched in 2011 with the main intention of understanding the water cycle in the tropical region and is a part of GPM constellation. MADRAS was the primary instrument on-board MT to estimate rainfall characteristics, but unfortunately it's scanning mechanism failed obscuring the primary goal of the mission.So an attempt has been made to retrieve rainfall and different hydrometeors using other instrument SAPHIR onboard MT. The most important advantage of using MT is its orbitography which is specifically designed for tropical regions and can reach up to 6 passes per day more than any other satellite currently in orbit. Although SAPHIR is an humidity sounder with six channels centred around 183 GHz channel, it still operates in the microwave region which directly interacts with rainfall, especially wing channels and thus can pick up rainfall signatures. Initial analysis using radiative transfer models also establish this fact .To get more conclusive results using observations, SAPHIR level 1 brightness temperature (BT) data was compared with different rainfall products utilizing the benefits of each product. SAPHIR BT comparison with TRMM 3B42 for one pass clearly showed that channel 5 and 6 have a considerable sensitivity towards rainfall. Following this a huge database of more than 300000 raining pixels of spatially and temporally collocated 3B42 rainfall and corresponding SAPHIR BT for an entire month was created to include all kinds of rainfall events, to attain higher temporal resolution collocated database was also created for SAPHIR BT and rainfall from infrared sensor on geostationary satellite Kalpana 1.These databases were used to understand response of various channels of SAPHIR to different rainfall regimes . TRMM 2A12 rainfall product was also used to identify capabilities of SAPHIR to retrieve cloud and ice water path which also gave significant correlation. Conclusively,we have shown that SAPHIR has

  17. SAPHIRE 8 Volume 3 - Users' Guide

    Energy Technology Data Exchange (ETDEWEB)

    C. L. Smith; K. Vedros; K. J. Kvarfordt

    2011-03-01

    The Systems Analysis Programs for Hands-on Integrated Reliability Evaluations (SAPHIRE) is a software application developed for performing a complete probabilistic risk assessment (PRA) using a personal computer. SAPHIRE is funded by the U.S. Nuclear Regulatory Commission (NRC) and developed by the Idaho National Laboratory (INL). The INL's primary role in this project is that of software developer. However, the INL also plays an important role in technology transfer by interfacing and supporting SAPHIRE users comprised of a wide range of PRA practitioners from the NRC, national laboratories, the private sector, and foreign countries. SAPHIRE can be used to model a complex system’s response to initiating events, quantify associated damage outcome frequencies, and identify important contributors to this damage (Level 1 PRA) and to analyze containment performance during a severe accident and quantify radioactive releases (Level 2 PRA). It can be used for a PRA evaluating a variety of operating conditions, for example, for a nuclear reactor at full power, low power, or at shutdown conditions. Furthermore, SAPHIRE can be used to analyze both internal and external initiating events and has special features for transforming models built for internal event analysis to models for external event analysis. It can also be used in a limited manner to quantify risk in terms of release consequences to both the public and the environment (Level 3 PRA). This reference guide will introduce the SAPHIRE Version 8.0 software. A brief discussion of the purpose and history of the software is included along with general information such as installation instructions, starting and stopping the program, and some pointers on how to get around inside the program. Next, database concepts and structure are discussed. Following that discussion are nine sections, one for each of the menu options on the SAPHIRE main menu, wherein the purpose and general capabilities for each option are

  18. Quality assessment and assimilation of Megha-Tropiques SAPHIR radiances into WRF assimilation system

    Science.gov (United States)

    Singh, Randhir; Ojha, Satya P.; Kishtawal, C. M.; Pal, P. K.

    2013-07-01

    This study presents an initial assessment of the quality of radiances measured from SAPHIR (Sounder for Probing Vertical Profiles of Humidity) on board Megha-Tropiques (Indo-French joint satellite), launched by the Indian Space Research Organisation on 12 October 2011. The radiances measured from SAPHIR are compared with those simulated by the radiative transfer model (RTM) using radiosondes measurements, Atmospheric Infrared Sounder retrievals, and National Centers for Environmental Prediction (NCEP) analyzed fields over the Indian subcontinent, during January to November 2012. The radiances from SAPHIR are also compared with the similar measurements available from Microwave Humidity Sounder (MHS) on board MetOp-A and NOAA-18/19 satellites, during January to November 2012. A limited comparison is also carried out between SAPHIR measured and the RTM computed radiances using European Centre for Medium-Range Weather Forecasts analyzed fields, during May and November 2012. The comparison of SAPHIR measured radiances with RTM simulated and MHS observed radiances reveals that SAPHIR observations are of good quality. After the initial assessment of the quality of the SAPHIR radiances, these radiances have been assimilated within the Weather Research and Forecasting (WRF) three-dimensional variational data assimilation system. Analysis/forecast cycling experiments with and without SAPHIR radiances are performed over the Indian region during the entire month of May 2012. The assimilation of SAPHIR radiances shows considerable improvements (with moisture analysis error reduction up to 30%) in the tropospheric analyses and forecast of moisture, temperature, and winds when compared to NCEP analyses and radiances measurement obtained from MHS, Advanced Microwave Sounding Unit-A, and High Resolution Infrared Sounder. Assimilation of SAPHIR radiances also resulted in substantial improvement in the precipitation forecast skill when compared with satellite-derived rain. Overall

  19. Systems analysis programs for Hands-on integrated reliability evaluations (SAPHIRE) Version 5.0: Verification and validation (V&V) manual. Volume 9

    Energy Technology Data Exchange (ETDEWEB)

    Jones, J.L.; Calley, M.B.; Capps, E.L.; Zeigler, S.L.; Galyean, W.J.; Novack, S.D.; Smith, C.L.; Wolfram, L.M. [Lockheed Idaho Technologies Co., Idaho Falls, ID (United States)

    1995-03-01

    A verification and validation (V&V) process has been performed for the System Analysis Programs for Hands-on Integrated Reliability Evaluation (SAPHIRE) Version 5.0. SAPHIRE is a set of four computer programs that NRC developed for performing probabilistic risk assessments. They allow an analyst to perform many of the functions necessary to create, quantify, and evaluate the risk associated with a facility or process being analyzed. The programs are Integrated Reliability and Risk Analysis System (IRRAS) System Analysis and Risk Assessment (SARA), Models And Results Database (MAR-D), and Fault tree, Event tree, and Piping and instrumentation diagram (FEP) graphical editor. Intent of this program is to perform a V&V of successive versions of SAPHIRE. Previous efforts have been the V&V of SAPHIRE Version 4.0. The SAPHIRE 5.0 V&V plan is based on the SAPHIRE 4.0 V&V plan with revisions to incorporate lessons learned from the previous effort. Also, the SAPHIRE 5.0 vital and nonvital test procedures are based on the test procedures from SAPHIRE 4.0 with revisions to include the new SAPHIRE 5.0 features as well as to incorporate lessons learned from the previous effort. Most results from the testing were acceptable; however, some discrepancies between expected code operation and actual code operation were identified. Modifications made to SAPHIRE are identified.

  20. Systems Analysis Programs for Hands-on Integrated Reliability Evaluations (SAPHIRE) Code Reference Manual

    Energy Technology Data Exchange (ETDEWEB)

    C. L. Smith; K. J. Kvarfordt; S. T. Wood

    2008-08-01

    The Systems Analysis Programs for Hands-on Integrated Reliability Evaluations (SAPHIRE) is a software application developed for performing a complete probabilistic risk assessment (PRA) using a personal computer. SAPHIRE is funded by the U.S. Nuclear Regulatory Commission (NRC) and developed by the Idaho National Laboratory (INL). The INL's primary role in this project is that of software developer. However, the INL also plays an important role in technology transfer by interfacing and supporting SAPHIRE users comprised of a wide range of PRA practitioners from the NRC, national laboratories, the private sector, and foreign countries. SAPHIRE can be used to model a complex system’s response to initiating events, quantify associated damage outcome frequencies, and identify important contributors to this damage (Level 1 PRA) and to analyze containment performance during a severe accident and quantify radioactive releases (Level 2 PRA). It can be used for a PRA evaluating a variety of operating conditions, for example, for a nuclear reactor at full power, low power, or at shutdown conditions. Furthermore, SAPHIRE can be used to analyze both internal and external initiating events and has special features for transforming models built for internal event analysis to models for external event analysis. It can also be used in a limited manner to quantify risk in terms of release consequences to both the public and the environment (Level 3 PRA). SAPHIRE includes a separate module called the Graphical Evaluation Module (GEM). GEM provides a highly specialized user interface with SAPHIRE that automates SAPHIRE process steps for evaluating operational events at commercial nuclear power plants. Using GEM, an analyst can estimate the risk associated with operational events in a very efficient and expeditious manner. This reference guide will introduce the SAPHIRE Version 7.0 software. A brief discussion of the purpose and history of the software is included along with

  1. Systems Analysis Programs for Hands-on Integrated Reliability Evaluations (SAPHIRE) Code Reference Manual

    Energy Technology Data Exchange (ETDEWEB)

    C. L. Smith; K. J. Kvarfordt; S. T. Wood

    2006-07-01

    The Systems Analysis Programs for Hands-on Integrated Reliability Evaluations (SAPHIRE) is a software application developed for performing a complete probabilistic risk assessment (PRA) using a personal computer. SAPHIRE is funded by the U.S. Nuclear Regulatory Commission (NRC) and developed by the Idaho National Laboratory (INL). The INL's primary role in this project is that of software developer. However, the INL also plays an important role in technology transfer by interfacing and supporting SAPHIRE users comprised of a wide range of PRA practitioners from the NRC, national laboratories, the private sector, and foreign countries. SAPHIRE can be used to model a complex system’s response to initiating events, quantify associated damage outcome frequencies, and identify important contributors to this damage (Level 1 PRA) and to analyze containment performance during a severe accident and quantify radioactive releases (Level 2 PRA). It can be used for a PRA evaluating a variety of operating conditions, for example, for a nuclear reactor at full power, low power, or at shutdown conditions. Furthermore, SAPHIRE can be used to analyze both internal and external initiating events and has special features for ansforming models built for internal event analysis to models for external event analysis. It can also be used in a limited manner to quantify risk in terms of release consequences to both the public and the environment (Level 3 PRA). SAPHIRE includes a separate module called the Graphical Evaluation Module (GEM). GEM provides a highly specialized user interface with SAPHIRE that automates SAPHIRE process steps for evaluating operational events at commercial nuclear power plants. Using GEM, an analyst can estimate the risk associated with operational events in a very efficient and expeditious manner. This reference guide will introduce the SAPHIRE Version 7.0 software. A brief discussion of the purpose and history of the software is included along with

  2. Systems Analysis Programs for Hands-on Integrated Reliability Evaluations (SAPHIRE) Data Loading Manual

    Energy Technology Data Exchange (ETDEWEB)

    C. L. Smith; K. J. Kvarfordt; S. T. Wood

    2006-07-01

    The Systems Analysis Programs for Hands-on Integrated Reliability Evaluations (SAPHIRE) is a software application developed for performing a complete probabilistic risk assessment (PRA) using a personal computer. SAPHIRE is primarily funded by the U.S. Nuclear Regulatory Commission (NRC) and developed by the Idaho National Laboratory. This report is intended to assist the user to enter PRA data into the SAPHIRE program using the built-in MAR-D ASCII-text file data transfer process. Towards this end, a small sample database is constructed and utilized for demonstration. Where applicable, the discussion includes how the data processes for loading the sample database relate to the actual processes used to load a larger PRA models. The procedures described herein were developed for use with SAPHIRE Version 6.0 and Version 7.0. In general, the data transfer procedures for version 6 and 7 are the same, but where deviations exist, the differences are noted. The guidance specified in this document will allow a user to have sufficient knowledge to both understand the data format used by SAPHIRE and to carry out the transfer of data between different PRA projects.

  3. SAPHIRE 8 Volume 6 - Quality Assurance

    Energy Technology Data Exchange (ETDEWEB)

    C. L. Smith; R. Nims; K. J. Kvarfordt

    2011-03-01

    The Systems Analysis Programs for Hands-on Integrated Reliability Evaluations (SAPHIRE) Version 8 is a software application developed for performing a complete probabilistic risk assessment using a personal computer running the Microsoft Windows™ operating system. SAPHIRE 8 is funded by the U.S. Nuclear Regulatory Commission (NRC). The role of the INL in this project is that of software developer and tester. This development takes place using formal software development procedures and is subject to quality assurance (QA) processes. The purpose of this document is to describe how the SAPHIRE software QA is performed for Version 8, what constitutes its parts, and limitations of those processes. In addition, this document describes the Independent Verification and Validation that was conducted for Version 8 as part of an overall QA process.

  4. Systems Analysis Programs for Hands-on Intergrated Reliability Evaluations (SAPHIRE) Summary Manual

    Energy Technology Data Exchange (ETDEWEB)

    C. L. Smith

    2008-08-01

    The Systems Analysis Programs for Hands-on Integrated Reliability Evaluations (SAPHIRE) is a software application developed for performing a complete probabilistic risk assessment (PRA) using a personal computer (PC) running the Microsoft Windows operating system. SAPHIRE is primarily funded by the U.S. Nuclear Regulatory Commission (NRC) and developed by the Idaho National Laboratory (INL). INL's primary role in this project is that of software developer and tester. However, INL also plays an important role in technology transfer by interfacing and supporting SAPHIRE users, who constitute a wide range of PRA practitioners from the NRC, national laboratories, the private sector, and foreign countries. SAPHIRE can be used to model a complex system’s response to initiating events and quantify associated consequential outcome frequencies. Specifically, for nuclear power plant applications, SAPHIRE can identify important contributors to core damage (Level 1 PRA) and containment failure during a severe accident which lead to releases (Level 2 PRA). It can be used for a PRA where the reactor is at full power, low power, or at shutdown conditions. Furthermore, it can be used to analyze both internal and external initiating events and has special features for transforming an internal events model to a model for external events, such as flooding and fire analysis. It can also be used in a limited manner to quantify risk in terms of release consequences to the public and environment (Level 3 PRA). SAPHIRE also includes a separate module called the Graphical Evaluation Module (GEM). GEM is a special user interface linked to SAPHIRE that automates the SAPHIRE process steps for evaluating operational events at commercial nuclear power plants. Using GEM, an analyst can estimate the risk associated with operational events (for example, to calculate a conditional core damage probability) very efficiently and expeditiously. This report provides an overview of the functions

  5. SAPHIRE 8 Software Configuration Management Plan

    Energy Technology Data Exchange (ETDEWEB)

    Curtis Smith

    2010-01-01

    The INL software developers use version control for both the formally released SAPHIRE versions, as well as for source code. For each formal release of the software, the developers perform an acceptance test: the software must pass a suite of automated tests prior to official release. Each official release of SAPHIRE is assigned a unique version identifier. The release is bundled into a standard installation package for easy and consistent set-up by individual users. Included in the release is a list of bug fixes and new features for the current release, as well as a history of those items for past releases. Each formal release of SAPHIRE will have passed an acceptance test. In addition to assignment of a unique version identifier for an official software release, each source code file is kept in a controlled library. Source code is a collection of all the computer instructions written by developers to create the finished product. The library is kept on a server, where back-ups are regularly made. This document describes the configuration management approach used as part of the SAPHIRE development.

  6. Investigation of Monoterpene Degradation in the Atmospheric Simulation Chamber SAPHIR

    Science.gov (United States)

    Kaminski, Martin; Acir, Ismail-Hakki; Bohn, Birger; Brauers, Theo; Dorn, Hans-Peter; Fuchs, Hendrik; Haeseler, Rolf; Hofzumahaus, Andreas; Li, Xin; Lutz, Anna; Nehr, Sascha; Rohrer, Franz; Tillmann, Ralf; Wegener, Robert; Wahner, Andreas

    2013-04-01

    Monoterpenes are the volatile organic compound (VOC) species with the highest emission rates on a global scale beside isoprene. In the atmosphere these compounds are rapidly oxidized. Due to their high reactivity towards hydroxyl radicals (OH) they determine the radical chemistry under biogenic conditions if monoterpene concentration is higher than isoprene concentration. Recent field campaigns showed large discrepancies between measured and modeled OH concentration at low NOx conditions together with high reactivity of VOC towards OH (Hofzumahaus et al. 2009) especially in tropical forest areas (Lelieveld et al. 2008). These discrepancies were partly explained by new reaction pathways in the isoprene degradation mechanism (Whalley et al 2011). However, even an additional recycling rate of 2.7 was insufficient to explain the measured OH concentration. So other VOC species could be involved in a nonclassical OH recycling. Since the discrepancies in OH also occurred in the morning hours when the OH chemistry was mainly dominated by monoterpenes, it was assumed that also the degradation of monoterpenes may lead to OH recycling in the absence of NO. (Whalley et al 2011). The photochemical degradation of four monoterpene species was studied under high VOC reactivity and low NOx conditions in a dedicated series of experiments in the atmospheric simulation chamber SAPHIR from August to September 2012 to overcome the lack of mechanistic information for monoterpene degradation schemes. α-Pinene, β-pinene and limonene were chosen as most prominent representatives of this substance class. Moreover the degradation of myrcene was investigated due to its structural analogy to isoprene. The SAPHIR chamber was equipped with instrumentation to measure all important OH precursors (O3, HONO, HCHO), the parent VOC and their main oxidation products, radicals (OH, HO2, RO2), the total OH reactivity, and photolysis frequencies to investigate the degradation mechanism of monoterpenes in

  7. New developments in the Saphire computer codes

    Energy Technology Data Exchange (ETDEWEB)

    Russell, K.D.; Wood, S.T.; Kvarfordt, K.J. [Idaho Engineering Lab., Idaho Falls, ID (United States)] [and others

    1996-03-01

    The Systems Analysis Programs for Hands-on Integrated Reliability Evaluations (SAPHIRE) refers to a suite of computer programs that were developed to create and analyze a probabilistic risk assessment (PRA) of a nuclear power plant. Many recent enhancements to this suite of codes have been made. This presentation will provide an overview of these features and capabilities. The presentation will include a discussion of the new GEM module. This module greatly reduces and simplifies the work necessary to use the SAPHIRE code in event assessment applications. An overview of the features provided in the new Windows version will also be provided. This version is a full Windows 32-bit implementation and offers many new and exciting features. [A separate computer demonstration was held to allow interested participants to get a preview of these features.] The new capabilities that have been added since version 5.0 will be covered. Some of these major new features include the ability to store an unlimited number of basic events, gates, systems, sequences, etc.; the addition of improved reporting capabilities to allow the user to generate and {open_quotes}scroll{close_quotes} through custom reports; the addition of multi-variable importance measures; and the simplification of the user interface. Although originally designed as a PRA Level 1 suite of codes, capabilities have recently been added to SAPHIRE to allow the user to apply the code in Level 2 analyses. These features will be discussed in detail during the presentation. The modifications and capabilities added to this version of SAPHIRE significantly extend the code in many important areas. Together, these extensions represent a major step forward in PC-based risk analysis tools. This presentation provides a current up-to-date status of these important PRA analysis tools.

  8. SAPHIRE 8 Volume 2 - Technical Reference

    Energy Technology Data Exchange (ETDEWEB)

    C. L. Smith; S. T. Wood; W. J. Galyean; J. A. Schroeder; M. B. Sattison

    2011-03-01

    The Systems Analysis Programs for Hands-on Integrated Reliability Evaluations (SAPHIRE) refers to a set of computer programs that were developed to create and analyze probabilistic risk assessment (PRAs). Herein information is provided on the principles used in the construction and operation of Version 8.0 of the SAPHIRE system. This report summarizes the fundamental mathematical concepts of sets and logic, fault trees, and probability. This volume then describes the algorithms used to construct a fault tree and to obtain the minimal cut sets. It gives the formulas used to obtain the probability of the top event from the minimal cut sets, and the formulas for probabilities that apply for various assumptions concerning reparability and mission time. It defines the measures of basic event importance that SAPHIRE can calculate. This volume gives an overview of uncertainty analysis using simple Monte Carlo sampling or Latin Hypercube sampling, and states the algorithms used by this program to generate random basic event probabilities from various distributions. Also covered are enhance capabilities such as seismic analysis, Workspace algorithms, cut set "recovery," end state manipulation, and use of "compound events."

  9. Intercalibrating and Validating Saphir and Atms Observations

    Science.gov (United States)

    Moradi, I.; Ferraro, R. R.

    2014-12-01

    We present the results of evaluating observations from microwave instruments aboard the Suomi National Polar-orbiting Partnership (NPP, ATMS instrument) and Megha-Tropiques (SAPHIR instrument) satellites. ATMS is a cross-track microwave sounder that currently flying on the Suomi National Polar-orbiting Partnership (S-NPP) satellite, launched in October 2011, which is in a Sun-synchronous orbit with the ascending equatorial crossing time at 01:30 a.m. Megha-Tropiques, launched in Nov 2011, is a low-inclination satellite meaning that the satellite only visits the tropical band between 30 S and 30 N. SAPHIR is a microwave humidity sounder with 6 channels operating at the frequencies close to the water vapor absorption line at 183 GHz. Megha-Tropiques revisits the tropical regions several times a day and provide a great capability for inter-calibrating the observations with the polar orbiting satellites. The study includes inter-comparison and inter-calibration of observations of similar channels from the two instruments, evaluation of the satellite data using high-quality radiosonde data from Atmospheric Radiation Measurement Program and GPS Radio Occultaion Observations from COSMIC mission, as well as geolocation error correction. The results of this study are valuable for generating climate data records from these instruments as well as for extending current climate data records from similar instruments such as AMSU-B and MHS to the ATMS and SAPHIR instruments.

  10. Strangeness Photoproduction with the Saphir Detector

    CERN Document Server

    Menze, D W

    1997-01-01

    Statistically improved data of total cross sections and of angular distributions for differential cross sections and hyperon recoil polarizations of the reactions \\gamma p --> K^+ \\Lambda and \\gamma p --> K^+ \\Sigma^0 have been collected with the SAPHIR detector at photon energies between threshold and 2.0 GeV. Here total cross section data up to 1.5 GeV are presented. The opposite sign of \\Lambda and \\Sigma polarization and the change of sign between forward and backward direction could be confirmed by higher statistics. A steep threshold behaviour of the K^+ \\Lambda total cross section is observed.

  11. Systems Analysis Programs for Hands-on Integrated Reliability Evaluations (SAPHIRE) GEM Manual

    Energy Technology Data Exchange (ETDEWEB)

    C. L. Smith; J. Schroeder; S. T. Beck

    2008-08-01

    The Systems Analysis Programs for Hands-on Integrated Reliability Evaluations (SAPHIRE) is a software application developed for performing a complete probabilistic risk assessment (PRA) using a personal computer running the Microsoft Windows? operating system. SAPHIRE is primarily funded by the U.S. Nuclear Regulatory Commission (NRC) and developed by the Idaho National Laboratory (INL). The INL's primary role in this project is that of software developer and tester. Using the SAPHIRE analysis engine and relational database is a complementary program called GEM. GEM has been designed to simplify using existing PRA analysis for activities such as the NRC’s Accident Sequence Precursor program. In this report, the theoretical framework behind GEM-type calculations are discussed in addition to providing guidance and examples for performing evaluations when using the GEM software. As part of this analysis framework, the two types of GEM analysis are outlined, specifically initiating event (where an initiator occurs) and condition (where a component is failed for some length of time) assessments.

  12. OVERVIEW OF THE SAPHIRE PROBABILISTIC RISK ANALYSIS SOFTWARE

    Energy Technology Data Exchange (ETDEWEB)

    Smith, Curtis L.; Wood, Ted; Knudsen, James; Ma, Zhegang

    2016-10-01

    The Systems Analysis Programs for Hands-on Integrated Reliability Evaluations (SAPHIRE) is a software application developed for performing a complete probabilistic risk assessment (PRA) using a personal computer (PC) running the Microsoft Windows operating system. SAPHIRE Version 8 is funded by the U.S. Nuclear Regulatory Commission (NRC) and developed by the Idaho National Laboratory (INL). INL's primary role in this project is that of software developer and tester. However, INL also plays an important role in technology transfer by interfacing and supporting SAPHIRE users, who constitute a wide range of PRA practitioners from the NRC, national laboratories, the private sector, and foreign countries. In this paper, we provide an overview of the current technical capabilities found in SAPHIRE Version 8, including the user interface and enhanced solving algorithms.

  13. Retrieval and Validation of Upper Tropospheric Humidity from SAPHIR aboard Megha-Tropics

    Science.gov (United States)

    Mathew, Nizy; Krishna Moorthy, K.; Raju C, Suresh; Pillai Renju, Ramachandran; Oommen John, Viju

    Upper tropospheric humidity (UTH) has been derived from brightness temperature of SAPHIR payload aboard Megha-Tropiques (MT) mission. The channels of SAPHIR are very close to the water vapor absorption peak at 183.31GHz. First three channels at 183.31±0.2 GHz, 183.31±1.1 GHz and 183.31±2.8 are used for upper tropospheric humidity (UTH) studies. The channel at 183.31±0.2 GHz enables retrieval of humidity up to the highest altitude possible with the present nadir looking microwave humidity sounders. Transformation coefficients for the first three channels for all the incidence angles have been derived using the simulated brightness temperatures and Jocobians with Chevellier data set as input to the radiative transfer model ARTS. These coefficients are used to convert brightness temperatures to upper tropospheric humidity from different channels. A stringent deep convective cloud screeing has been done using the brightness temperatures of SAPHIR itself. The retrieved UTH has been validated with the Jacobian weighted UTH derived from collocated radiosonde observations and also with the humidity profiles derived from ground based microwave radiometer data. UTH variation over the inter-tropical region on global basis has been studied for one year, taking the advantage of the first humidity product with high spatial and temporal resolution over the tropical belt, unbiased with specific local times of the satellite pass. These data set have been used to adress the seasonal and spatial variability of humidity in the tropical upper tropospheric region and humidity variability during Indian monsoon. The details of the MT-SAPHIR characteristics, methodology and results will be presented. begin{enumerate} begin{center}

  14. Impact of Megha-Tropiques SAPHIR radiance assimilation on the simulation of tropical cyclones over Bay of Bengal

    Science.gov (United States)

    Dhanya, M.; Gopalakrishnan, Deepak; Chandrasekar, Anantharaman; Singh, Sanjeev Kumar; Prasad, V. S.

    2016-05-01

    Impact of SAPHIR radiance assimilation on the simulation of tropical cyclones over Indian region has been investigated using the Weather Research and Forecasting (WRF) model. Three cyclones that formed over Bay of Bengal have been considered in the present study. Assimilation methodology used here is the three dimensional variational (3DVar) scheme within the WRF model. With the initial and boundary conditions from Global Forecasting System (GFS) analyses from the National Centres for Environmental Prediction (NCEP), a control run (CTRL) without assimilation of any data and a 3DVar run with the assimilation of SAPHIR radiance have been performed. Both model simulations have been compared with the observations from India Meteorological Department (IMD), Tropical Rainfall Measurement Mission (TRMM), and analysis fields from GFS. Detailed analysis reveals that, the SAPHIR radiance assimilation has led to significant improvement in the simulation of all the three cyclones in terms of cyclone track, intensity, accumulated rainfall. The simulation of warm core structure and relative vorticity profile of each cyclone by 3DVar run are found to be more closer to GFS analyses, when compared with the CTRL run.

  15. SAPHIRE 8 Software Independent Verification and Validation Plan

    Energy Technology Data Exchange (ETDEWEB)

    Rae J. Nims; Kent M. Norris

    2010-02-01

    SAPHIRE 8 is being developed with a phased or cyclic iterative rapid application development methodology. Due to this approach, a similar approach is being taken for the IV&V activities on each vital software object. The IV&V plan is structured around NUREG/BR-0167, “Software Quality Assurance Program and Guidelines,” February 1993. The Nuclear Regulatory Research Office Instruction No.: PRM-12, “Software Quality Assurance for RES Sponsored Codes,” March 26, 2007 specifies that RES-sponsored software is to be evaluated against NUREG/BR-0167. Per the guidance in NUREG/BR-0167, SAPHIRE is classified as “Level 1.” Level 1 software corresponds to technical application software used in a safety decision.

  16. Independent Verification and Validation Of SAPHIRE 8 System Test Plan Project Number: N6423 U.S. Nuclear Regulatory Commission

    Energy Technology Data Exchange (ETDEWEB)

    Kent Norris

    2010-02-01

    The purpose of the Independent Verification and Validation (IV&V) role in the evaluation of the SAPHIRE System Test Plan is to assess the approach to be taken for intended testing activities associated with the SAPHIRE software product. The IV&V team began this endeavor after the software engineering and software development of SAPHIRE had already been in production.

  17. Systems Analysis Programs for Hands-on Integrated Reliability Evaluations (SAPHIRE) Tutorial

    Energy Technology Data Exchange (ETDEWEB)

    C. L. Smith; S. T. Beck; S. T. Wood

    2008-08-01

    The Systems Analysis Programs for Hands-on Integrated Reliability Evaluations (SAPHIRE) refers to a set of computer programs that were developed to create and analyze probabilistic risk assessment (PRAs). This volume is the tutorial manual for the SAPHIRE system. In this document, a series of lessons are provided that guide the user through basic steps common to most analyses preformed with SAPHIRE. The tutorial is divided into two major sections covering both basic and advanced features. The section covering basic topics contains lessons that lead the reader through development of a probabilistic hypothetical problem involving a vehicle accident, highlighting the program’s most fundamental features. The advanced features section contains additional lessons that expand on fundamental analysis features of SAPHIRE and provide insights into more complex analysis techniques. Together, these two elements provide an overview into the operation and capabilities of the SAPHIRE software.

  18. Rain detection and measurement from Megha-Tropiques microwave sounder—SAPHIR

    Science.gov (United States)

    Varma, Atul Kumar; Piyush, D. N.; Gohil, B. S.; Pal, P. K.; Srinivasan, J.

    2016-08-01

    The Megha-Tropiques, an Indo-French satellite, carries on board a microwave sounder, Sondeur Atmosphérique du Profil d'Humidité Intertropical par Radiométrie (SAPHIR), and a microwave radiometer, Microwave Analysis and Detection of Rain and Atmospheric Structures (MADRAS), along with two other instruments. Being a Global Precipitation Measurement constellation satellite MT-MADRAS was an important sensor to study the convective clouds and rainfall. Due to the nonfunctioning of MADRAS, the possibility of detection and estimation of rain from SAPHIR is explored. Using near-concurrent SAPHIR and precipitation radar (PR) onboard Tropical Rainfall Measuring Mission (TRMM) observations, the rain effect on SAPHIR channels is examined. All the six channels of the SAPHIR are used to calculate the average rain probability (PR) for each SAPHIR pixel. Further, an exponential rain retrieval algorithm is developed. This algorithm explains a correlation of 0.72, RMS error of 0.75 mm/h, and bias of 0.04 mm/h. When rain identification and retrieval algorithms are applied together, it explains a correlation of 0.69 with an RMS error of 0.47 mm/h and bias of 0.01 mm/h. On applying the algorithm to the independent SAPHIR data set and compared with TRMM-3B42 rain on monthly scale, it explains a correlation of 0.85 and RMS error of 0.09 mm/h. Further distribution of rain difference of SAPHIR with other rain products is presented on global scale as well as for the climatic zones. For examining the capability of SAPHIR to measure intense rain, instantaneous rain over Phailin cyclone from SAPHIR is compared with other standard satellite-based rain products such as 3B42, Global Satellite Mapping of Precipitation, and Precipitation Estimation from Remote Sensing Information using Artificial Neural Network.

  19. Megha-Tropiques/SAPHIR measurements of humidity profiles: validation with AIRS and global radiosonde network

    Science.gov (United States)

    Subrahmanyam, K. V.; Kumar, K. K.

    2013-12-01

    The vertical profiles of humidity measured by SAPHIR (Sondeur Atmospherique du Profil d' Humidité Intropicale par Radiométrie) on-board Megha-Tropiques satellite are validated using Atmosphere Infrared Sounder (AIRS) and ground based radiosonde observations during July-September 2012. SAPHIR provides humidity profiles at six pressure layers viz., 1000-850 (level 1), 850-700 (level 2), 700-550 (level 3), 550-400 (level 4) 400-250 (level 5) and 250-100(level 6) hPa. Segregated AIRS observations over land and oceanic regions are used to assess the performance of SAPHIR quantitatively. The regression analysis over oceanic region (125° W-180° W; 30° S-30° N) reveal that the SAPHIR measurements agrees very well with the AIRS measurements at levels 3, 4, 5 and 6 with correlation coefficients 0.79, 0.88, 0.87 and 0.78 respectively. However, at level 6 SAPHIR seems to be systematically underestimating the AIRS measurements. At level 2, the agreement is reasonably good with correlation coefficient of 0.52 and at level 1 the agreement is very poor with correlation coefficient 0.17. The regression analysis over land region (10° W-30° E; 8° N-30° N) revealed an excellent correlation between AIRS and SAPHIR at all the six levels with 0.80, 0.78, 0.84, 0.84, 0.86 and 0.65 respectively. However, again at levels 5 and 6, SAPHIR seems to be underestimating the AIRS measurements. After carrying out the quantitative comparison between SAPHIR and AIRS separately over land and ocean, the ground based global radiosonde network observations of humidity profiles over three distinct geographical locations (East Asia, tropical belt of South and North America and South Pacific) are then used to further validate the SAPHIR observations as AIRS has its own limitations. The SAPHIR observations within a radius of 50 km around the radiosonde stations are averaged and then the regression analysis is carried out at the first five levels of SAPHIR. The comparison is not carried out at sixth

  20. Systems Analysis Programs for Hands-on Integrated Reliability Evaluations (SAPHIRE) Quality Assurance Manual

    Energy Technology Data Exchange (ETDEWEB)

    C. L. Smith; R. Nims; K. J. Kvarfordt; C. Wharton

    2008-08-01

    The Systems Analysis Programs for Hands-on Integrated Reliability Evaluations (SAPHIRE) is a software application developed for performing a complete probabilistic risk assessment using a personal computer running the Microsoft Windows operating system. SAPHIRE is primarily funded by the U.S. Nuclear Regulatory Commission (NRC). The role of the INL in this project is that of software developer and tester. This development takes place using formal software development procedures and is subject to quality assurance (QA) processes. The purpose of this document is to describe how the SAPHIRE software QA is performed for Version 6 and 7, what constitutes its parts, and limitations of those processes.

  1. $K^0$-$\\Sigma^+$ Photoproduction with SAPHIR

    CERN Document Server

    Bennhold, C

    1998-01-01

    Preliminary results of the analysis of the reaction p(gamma,K0)Sigma+ are presented. We show the first measurement of the differential cross section and much improved data for the total cross section than previous data. The data are compared with model predictions from different isobar and quark models that give a good description of p(gamma,K+)Lambda and p(gamma,K+)Sigma0 data in the same energy range. None of the models yield an adequate description of the data at all energies.

  2. SAPHIRE: A New Flat-Panel Digital Mammography Detector With Avalanche Photoconductor and High-Resolution Field Emitter Readout

    Science.gov (United States)

    2006-06-01

    AD_________________ Award Number: W81XWH-04-1-0554 TITLE: SAPHIRE : A New Flat-Panel Digital... SAPHIRE : A New Flat-Panel Digital Mammography Detector with Avalanche Photoconductor and High-Resolution Field Emitter Readout 5b. GRANT NUMBER w81xwh-04...CsI), and form a charge image that is read out by a high-resolution field emitter array (FEA). We call the proposed detector SAPHIRE (Scintillator

  3. Type 2 diabetes models

    DEFF Research Database (Denmark)

    Gram, Dorte Xenia

    2012-01-01

    This chapter deals with type 2 diabetes in vivo models and techniques suitable for testing new anti-diabetic compounds. In particular, the testing of TRP antagonist for beneficial effects against type 2 diabetes is considered. There are many choices of both in vitro techniques and in vivo models......, impaired glucose tolerance, impaired insulin secretion, and insulin resistance in vivo and should, thus, be sufficient to demonstrate preclinical proof of concept of a TRP antagonist in type 2 diabetes in rodents. The experiments are suggestions and could be replaced or supplemented by others....

  4. Evaluation of SAPHIR / Megha-Tropiques observations - CINDY/DYNAMO Campaign

    Science.gov (United States)

    Clain, Gaelle; Brogniez, Hélène; John, Viju; Payne, Vivienne; Luo, Ming

    2014-05-01

    The SAPHIR sounder (Sondeur Atmosphérique du Profil d'Humidité Intertropicale par Radiométrie) onboard the Megha-Tropiques (MT) platform observes the microwave radiation emitted by the Earth system in the strong absorption line of water vapor at 183.31 GHz. It is a multi-channel microwave humidity sounder with 6 channels in the 183.31GHz water vapor absorption band, a maximum scan angle of 42.96° around nadir, a 1700 km wide swath and a footprint resolution of 10 km at nadir. A comparison between the sensor L1A2 observations and radiative transfer calculations using in situ measurements from radiosondes as input is performed in order to validate the satellite observations on the brightness temperature (BT) level. The radiosonde humidity observations chosen as reference were performed during the CINDY/DYNAMO campaign (september 2011 to March 2012) with Vaïsala RS92-SGPD probes and match to a spatio-temporal co-location with MT satellite overpasses. Although several sonde systems were used during the campaign, all of the sites selected for this study used the Vaïsala RS92-SGPD system and were chosen in order to avoid discrepancies in data quality and biases. This work investigates the difference - or bias - between the BTs observed by the sensor and BT simulations from a radiative transfer model, RTTOV-10. The bias amplitude is characterized by a temperature dependent pattern, increasing from nearly 0 Kelvin for the 183.31 ± 0.2 channel to a range of 2 K for the 183.31 ± 11 channel. However the comparison between the sensor data and the radiative transfer simulations is not straightforward and uncertainties associated to the data processing must be propagated throughout the evaluation. Therefore this work documents an evaluation of the uncertainties and errors that can impact the BT bias. These can be linked to the radiative transfer model input and design, the radiosonde observations, the methodology chosen for the comparison and the SAPHIR instrument itself.

  5. Investigation of isoprene oxidation in the atmosphere simulation chamber SAPHIR at low NO concentrations

    Science.gov (United States)

    Fuchs, H.; Rohrer, F.; Hofzumahaus, A.; Bohn, B.; Brauers, T.; Dorn, H.; Häseler, R.; Holland, F.; Li, X.; Lu, K.; Nehr, S.; Tillmann, R.; Wahner, A.

    2012-12-01

    During recent field campaigns, hydroxyl radical (OH) concentrations that were measured by laser-induced fluorescence spectroscopy (LIF) were up to a factor of ten larger than predicted by current chemical models for conditions of high OH reactivity and low nitrogen monoxide (NO) concentrations. These discrepancies were observed in the Pearl-River-Delta, China, which is an urban-influenced rural area, in rainforests, and forested areas in North America and Europe. Isoprene contributed significantly to the total OH reactivity in these field studies, so that potential explanations for the missing OH focused on new reaction pathways in the isoprene degradation mechanism. These pathways regenerate OH without oxidation of NO and thus without ozone production. In summer 2011, a series of experiments was carried out in the atmosphere simulation chamber SAPHIR in Juelich, Germany, in order to investigate the photochemical degradation of isoprene at low NO concentrations (NOSAPHIR by established chemical models like the Master Chemical Mechanism (MCM). Moreover, OH concentration measurements of two independent instruments (LIF and DOAS) agreed during all chamber experiments. Here, we present the results of the experiments and compare measurements with model predictions using the MCM. Furthermore, the validity of newly proposed reaction pathways in the isoprene degradation is evaluated by comparison with observations.

  6. Technical Note: Intercomparison of formaldehyde measurements at the atmosphere simulation chamber SAPHIR

    Directory of Open Access Journals (Sweden)

    A. Wisthaler

    2007-11-01

    Full Text Available The atmosphere simulation chamber SAPHIR at the Research Centre Jülich was used to test the suitability of state-of-the-art analytical instruments for the measurement of gas-phase formaldehyde (HCHO in air. Five analyzers based on four different sensing principles were deployed: a differential optical absorption spectrometer (DOAS, cartridges for 2,4-dinitro-phenyl-hydrazine (DNPH derivatization followed by off-line high pressure liquid chromatography (HPLC analysis, two different types of commercially available wet chemical sensors based on Hantzsch fluorimetry, and a proton-transfer-reaction mass spectrometer (PTR-MS. A new optimized mode of operation was used for the PTR-MS instrument which significantly enhanced its performance for on-line HCHO detection at low absolute humidities.

    The instruments were challenged with typical ambient levels of HCHO ranging from zero to several ppb. Synthetic air of high purity and particulate-filtered ambient air were used as sample matrices in the atmosphere simulation chamber onto which HCHO was spiked under varying levels of humidity and ozone. Measurements were compared to mixing ratios calculated from the chamber volume and the known amount of HCHO injected into the chamber; measurements were also compared between the different instruments. The formal and blind intercomparison exercise was conducted under the control of an independent referee. A number of analytical problems associated with the experimental set-up and with individual instruments were identified, the overall agreement between the methods was good.

  7. Technical Note: Intercomparison of formaldehyde measurements at the atmosphere simulation chamber SAPHIR

    Science.gov (United States)

    Wisthaler, A.; Apel, E. C.; Bossmeyer, J.; Hansel, A.; Junkermann, W.; Koppmann, R.; Meier, R.; Müller, K.; Solomon, S. J.; Steinbrecher, R.; Tillmann, R.; Brauers, T.

    2008-04-01

    The atmosphere simulation chamber SAPHIR at the Research Centre Jülich was used to test the suitability of state-of-the-art analytical instruments for the measurement of gas-phase formaldehyde (HCHO) in air. Five analyzers based on four different sensing principles were deployed: a differential optical absorption spectrometer (DOAS), cartridges for 2,4-dinitrophenylhydrazine (DNPH) derivatization followed by off-line high pressure liquid chromatography (HPLC) analysis, two different types of commercially available wet chemical sensors based on Hantzsch fluorimetry, and a proton-transfer-reaction mass spectrometer (PTR-MS). A new optimized mode of operation was used for the PTR-MS instrument which significantly enhanced its performance for online HCHO detection at low absolute humidities. The instruments were challenged with typical ambient levels of HCHO ranging from zero to several ppb. Synthetic air of high purity and particulate-filtered ambient air were used as sample matrices in the atmosphere simulation chamber onto which HCHO was spiked under varying levels of humidity and ozone. Measurements were compared to mixing ratios calculated from the chamber volume and the known amount of HCHO injected into the chamber; measurements were also compared between the different instruments. The formal and blind intercomparison exercise was conducted under the control of an independent referee. A number of analytical problems associated with the experimental set-up and with individual instruments were identified, the overall agreement between the methods was fair.

  8. Technical Note: Intercomparison of formaldehyde measurements at the atmosphere simulation chamber SAPHIR

    Directory of Open Access Journals (Sweden)

    A. Wisthaler

    2008-04-01

    Full Text Available The atmosphere simulation chamber SAPHIR at the Research Centre Jülich was used to test the suitability of state-of-the-art analytical instruments for the measurement of gas-phase formaldehyde (HCHO in air. Five analyzers based on four different sensing principles were deployed: a differential optical absorption spectrometer (DOAS, cartridges for 2,4-dinitro-phenyl-hydrazine (DNPH derivatization followed by off-line high pressure liquid chromatography (HPLC analysis, two different types of commercially available wet chemical sensors based on Hantzsch fluorimetry, and a proton-transfer-reaction mass spectrometer (PTR-MS. A new optimized mode of operation was used for the PTR-MS instrument which significantly enhanced its performance for online HCHO detection at low absolute humidities.

    The instruments were challenged with typical ambient levels of HCHO ranging from zero to several ppb. Synthetic air of high purity and particulate-filtered ambient air were used as sample matrices in the atmosphere simulation chamber onto which HCHO was spiked under varying levels of humidity and ozone. Measurements were compared to mixing ratios calculated from the chamber volume and the known amount of HCHO injected into the chamber; measurements were also compared between the different instruments. The formal and blind intercomparison exercise was conducted under the control of an independent referee. A number of analytical problems associated with the experimental set-up and with individual instruments were identified, the overall agreement between the methods was fair.

  9. Investigation of MACR oxidation by OH in the atmosphere simulation chamber SAPHIR at low NO concentrations.

    Science.gov (United States)

    Fuchs, Hendrik; Acir, Ismail-Hakki; Bohn, Birger; Brauers, Theo; Dorn, Hans-Peter; Häseler, Rolf; Hofzumahaus, Andreas; Holland, Frank; Li, Xin; Lu, Keding; Lutz, Anna; Kaminski, Martin; Nehr, Sascha; Rohrer, Franz; Tillmann, Ralf; Wegener, Robert; Wahner, Andreas

    2013-04-01

    During recent field campaigns, hydroxyl radical (OH) concentrations were up to a factor of ten larger than predicted by current chemical models for conditions of high OH reactivity and low nitrogen monoxide (NO) concentrations. These discrepancies were observed in forests, where isoprene oxidation turnover rates were large. Methacrolein (MACR) is one of the major first generation products of isoprene oxidation, so that MACR was also an important reactant for OH. Here, we present a detailed investigation of the MACR oxidation mechanism including a full set of accurate and precise radical measurements in the atmosphere simulation chamber SAPHIR in Juelich, Germany. The conditions during the chamber experiments were comparable to those during field campaigns with respect to radical and trace gas concentrations. In particular, OH reactivity was as high as 15 per second and NO mixing ratios were as low as 200pptv. Results of the experiments were compared to model predictions using the Master Chemical Mechanism, in order to identify so far unknown reaction pathways, which potentially recycle OH radicals without reactions with NO.

  10. Inter-calibration and validation of observations from SAPHIR and ATMS instruments

    Science.gov (United States)

    Moradi, I.; Ferraro, R. R.

    2015-12-01

    We present the results of evaluating observations from microwave instruments aboard the Suomi National Polar-orbiting Partnership (NPP, ATMS instrument) and Megha-Tropiques (SAPHIR instrument) satellites. The study includes inter-comparison and inter-calibration of observations of similar channels from the two instruments, evaluation of the satellite data using high-quality radiosonde data from Atmospheric Radiation Measurement Program and GPS Radio Occultaion Observations from COSMIC mission, as well as geolocation error correction. The results of this study are valuable for generating climate data records from these instruments as well as for extending current climate data records from similar instruments such as AMSU-B and MHS to the ATMS and SAPHIR instruments. Reference: Moradi et al., Intercalibration and Validation of Observations From ATMS and SAPHIR Microwave Sounders. IEEE Transactions on Geoscience and Remote Sensing. 01/2015; DOI: 10.1109/TGRS.2015.2427165

  11. Gerasimov-Drell-Hearn Sum Rule and the Discrepancy between the New CLAS and SAPHIR Data

    CERN Document Server

    Mart, T

    2008-01-01

    Contribution of the K^+\\Lambda channel to the Gerasimov-Drell-Hearn (GDH) sum rule has been calculated by using the models that fit the recent SAPHIR or CLAS differential cross section data. It is shown that the two data sets yield quite different contributions. Contribution of this channel to the forward spin polarizability of the proton has been also calculated. It is also shown that the inclusion of the recent CLAS C_x and C_z data in the fitting data base does not significantly change the result of the present calculation. Results of the fit, however, reveal the role of the S_{11}(1650), P_{11}(1710), P_{13}(1720), and P_{13}(1900) resonances for the description of the C_x and C_z data. A brief discussion on the importance of these resonances is given. Measurements of the polarized total cross section \\sigma_{TT'} by the CLAS, LEPS, and MAMI collaborations are expected to verify this finding.

  12. SAPHIRE (scintillator avalanche photoconductor with high resolution emitter readout) for low dose x-ray imaging: spatial resolution.

    Science.gov (United States)

    Li, Dan; Zhao, Wei

    2008-07-01

    An indirect flat panel imager (FPI) with programmable avalanche gain and field emitter array (FEA) readout is being investigated for low-dose and high resolution x-ray imaging. It is made by optically coupling a structured x-ray scintillator, e.g., thallium (Tl) doped cesium iodide (CsI), to an amorphous selenium (a-Se) avalanche photoconductor called high-gain avalanche rushing amorphous photoconductor (HARP). The charge image created by the scintillator/HARP (SHARP) combination is read out by the electron beams emitted from the FEA. The proposed detector is called scintillator avalanche photoconductor with high resolution emitter readout (SAPHIRE). The programmable avalanche gain of HARP can improve the low dose performance of indirect FPI while the FEA can be made with pixel sizes down to 50 microm. Because of the avalanche gain, a high resolution type of CsI (Tl), which has not been widely used in indirect FPI due to its lower light output, can be used to improve the high spatial frequency performance. The purpose of the present article is to investigate the factors affecting the spatial resolution of SAPHIRE. Since the resolution performance of the SHARP combination has been well studied, the focus of the present work is on the inherent resolution of the FEA readout method. The lateral spread of the electron beam emitted from a 50 microm x 50 microm pixel FEA was investigated with two different electron-optical designs: mesh-electrode-only and electrostatic focusing. Our results showed that electrostatic focusing can limit the lateral spread of electron beams to within the pixel size of down to 50 microm. Since electrostatic focusing is essentially independent of signal intensity, it will provide excellent spatial uniformity.

  13. Independent Verification and Validation SAPHIRE Version 8 Final Report Project Number: N6423 U.S. Nuclear Regulatory Commission

    Energy Technology Data Exchange (ETDEWEB)

    Kent Norris

    2010-04-01

    This report provides an evaluation of the SAPHIRE version 8 software product. SAPHIRE version 8 is being developed with a phased or cyclic iterative rapid application development methodology. Due to this approach, a similar approach has been taken for the IV&V activities on each vital software object. IV&V and Software Quality Assurance (SQA) activities occur throughout the entire development life cycle and therefore, will be required through the full development of SAPHIRE version 8. Later phases of the software life cycle, the operation and maintenance phases, are not applicable in this effort since the IV&V is being done prior to releasing Version 8.

  14. New insights into the degradation of terpenoids with OH: a study of the OH budget in the atmosphere simulation chamber SAPHIR

    Science.gov (United States)

    Kaminski, Martin; Fuchs, Hendrik; Acir, Ismail-Hakki; Bohn, Birger; Brauers, Theo; Dorn, Hans-Peter; Häseler, Rolf; Hofzumahaus, Andreas; Li, Xin; Lutz, Anna; Nehr, Sascha; Rohrer, Franz; Tillmann, Ralf; Wegener, Robert; Kiendler-Scharr, Astrid; Wahner, Andreas

    2014-05-01

    The hydroxyl radical (OH) is the main oxidation agent in the atmosphere during daytime. Recent field campaigns studying the radical chemistry in forested areas showed large discrepancies between measured and modeled OH concentration at low NOx conditions and when OH reactivity was dominated by VOC. These observations were only partially explained by the evidence for new efficient hydroxyl radical regeneration pathways in the isoprene oxidation mechanism. The question arises if other reactive VOCs with high global emission rates are also capable of additional OH recycling. Beside isoprene, monoterpenes and 2-methyl-3-buten-2-ol (MBO) are the volatile organic compounds (VOC) with the highest global emission rates. Due to their high reactivity towards OH monoterpenes and MBO can dominate the radical chemistry of the atmosphere in forested areas under certain conditions. In the present study the photochemical degradation mechanism of α-pinene, β-pinene, limonene, myrcene and MBO was investigated in the Jülich atmosphere simulation chamber SAPHIR. The focus of this study was in particular on the investigation of the OH budget in the degradation process. The photochemical degradation of these terpenoids was studied in a dedicated series of experiments in the years 2012 and 2013. The SAPHIR chamber was equipped with instrumentation to measure radicals (OH, HO2, RO2), the total OH reactivity, all important OH precursors (O3, HONO, HCHO), the parent VOC, its main oxidation products and photolysis frequencies to investigate the radical budget in the SAPHIR chamber. All experiments were carried out under low NOx conditions (≤ 2ppb) and atmospheric terpenoid concentrations (≤ 5ppb) with and without addition of ozone into the SAPHIR chamber. For the investigation of the OH budget all measured OH production terms were compared to the measured OH destruction. Within the limits of accuracy of the instruments the OH budget was balanced in all cases. Consequently unaccounted

  15. Retrieval of cloud ice water path using SAPHIR on board Megha-Tropiques over the tropical ocean

    Science.gov (United States)

    Piyush, Durgesh Nandan; Goyal, Jayesh; Srinivasan, J.

    2017-04-01

    The SAPHIR sensor onboard Megha-Tropiques (MT) measures the earth emitted radiation at frequencies near the water vapor absorption band. SAPHIR operates in six frequencies ranging from 183 ± 0.1 to 183 ± 11 GHz. These frequencies have been used to retrieve cloud ice water path (IWP) at a very high resolution. A method to retrieve IWP over the Indian ocean region is attempted in this study. The study is in two parts, in first part a radiative transfer based simulation is carried out to give an insight of using SAPHIR frequency channels for IWP retrieval, in the next part the real observations of SAPHIR and TRMM-TMI was used for IWP retrieval. The concurrent observations of SAPHIR brightness temperatures (Tbs) and TRMM TMI IWP were used in the development of the retrieval algorithm. An Eigen Vector analysis was done to identify weight of each channel in retrieving IWP; following this a two channel regression based algorithm was developed. The SAPHIR channels which are away from the water vapor absorption band were used to avoid possible water vapor contamination. When the retrieval is compared with independent test dataset, it gives a correlation of 0.80 and RMSE of 3.5%. SAPHIR derived IWP has been compared with other available global IWP products such as TMI, MSPPS, CloudSat and GPM-GMI qualitatively as well as quantitatively. PDF comparison of SAPHIR derived IWP found to have good agreement with CloudSat. Zonal mean comparison with recently launched GMI shows the strength of this algorithm.

  16. Atmospheric photochemistry of aromatic hydrocarbons: OH budgets during SAPHIR chamber experiments

    Science.gov (United States)

    Nehr, S.; Bohn, B.; Dorn, H.-P.; Fuchs, H.; Häseler, R.; Hofzumahaus, A.; Li, X.; Rohrer, F.; Tillmann, R.; Wahner, A.

    2014-07-01

    Current photochemical models developed to simulate the atmospheric degradation of aromatic hydrocarbons tend to underestimate OH radical concentrations. In order to analyse OH budgets, we performed experiments with benzene, toluene, p-xylene and 1,3,5-trimethylbenzene in the atmosphere simulation chamber SAPHIR. Experiments were conducted under low-NO conditions (typically 0.1-0.2 ppb) and high-NO conditions (typically 7-8 ppb), and starting concentrations of 6-250 ppb of aromatics, dependent on OH rate constants. For the OH budget analysis a steady-state approach was applied in which OH production and destruction rates (POH and DOH) have to be equal. The POH were determined from measurements of HO2, NO, HONO, and O3 concentrations, considering OH formation by photolysis and recycling from HO2. The DOH were calculated from measurements of the OH concentrations and total OH reactivities. The OH budgets were determined from DOH/POH ratios. The accuracy and reproducibility of the approach were assessed in several experiments using CO as a reference compound where an average ratio DOH/POH = 1.13 ± 0.19 was obtained. In experiments with aromatics, these ratios ranged within 1.1-1.6 under low-NO conditions and 0.9-1.2 under high-NO conditions. The results indicate that OH budgets during photo-oxidation experiments with aromatics are balanced within experimental accuracies. Inclusion of a further, recently proposed OH production via HO2 + RO2 reactions led to improvements under low-NO conditions but the differences were small and insignificant within the experimental errors.

  17. Le disque à saphir dans l’édition phonographique – Première partie

    OpenAIRE

    Sébald, Bruno

    2010-01-01

    L’expression « disque à saphir » que nous emploierons dans cet article recouvre un terme générique utilisé pour décrire des disques plats lus, à l’origine, par le truchement d’un saphir de forme sphérique. Cette technique relève d’un procédé de gravure verticale et se démarque ainsi du disque à aiguille, dont la pointe de lecture diffère et dont le mode de gravure est latéral. Elle s’en distingue également physiquement par la texture perlée qui couvre la surface du disque. Historiquement, le ...

  18. Systems Analysis Programs for Hands-On Integrated Reliability Evaluations (SAPHIRE) Technical Reference

    Energy Technology Data Exchange (ETDEWEB)

    C. L. Smith; W. J. Galyean; S. T. Beck

    2008-08-01

    The Systems Analysis Programs for Hands-on Integrated Reliability Evaluations (SAPHIRE) is a software application developed for performing a complete probabilistic risk assessment (PRA) using a personal computer (PC) running the Microsoft Windows? operating system. Herein information is provided on the principles used in the construction and operation of Version 6.0 and 7.0 of the SAPHIRE system. This report summarizes the fundamental mathematical concepts of sets and logic, fault trees, and probability. This volume then describes the algorithms used to construct a fault tree and to obtain the minimal cut sets. It gives the formulas used to obtain the probability of the top event from the minimal cut sets, and the formulas for probabilities that apply for various assumptions concerning reparability and mission time. It defines the measures of basic event importance that SAPHIRE can calculate. This volume gives an overview of uncertainty analysis using simple Monte Carlo sampling or Latin Hypercube sampling, and states the algorithms used by this program to generate random basic event probabilities from various distributions. Also covered are enhance capabilities such as seismic analysis, cut set "recovery," end state manipulation, and use of "compound events."

  19. Systems Analysis Programs for Hands-On Integrated Reliability Evaluations (SAPHIRE) Technical Reference Manual

    Energy Technology Data Exchange (ETDEWEB)

    C. L. Smith; W. J. Galyean; S. T. Beck

    2006-07-01

    The Systems Analysis Programs for Hands-on Integrated Reliability Evaluations (SAPHIRE) is a software application developed for performing a complete probabilistic risk assessment (PRA) using a personal computer (PC) running the Microsoft Windows? operating system. Herein information is provided on the principles used in the construction and operation of Version 6.0 and 7.0 of the SAPHIRE system. This report summarizes the fundamental mathematical concepts of sets and logic, fault trees, and probability. This volume then describes the algorithms used to construct a fault tree and to obtain the minimal cut sets. It gives the formulas used to obtain the probability of the top event from the minimal cut sets, and the formulas for probabilities that apply for various assumptions concerning reparability and mission time. It defines the measures of basic event importance that SAPHIRE can calculate. This volume gives an overview of uncertainty analysis using simple Monte Carlo sampling or Latin Hypercube sampling, and states the algorithms used by this program to generate random basic event probabilities from various distributions. Also covered are enhance capabilities such as seismic analysis, cut set "recovery," end state manipulation, and use of "compound events."

  20. Type IV Wind Turbine Model

    DEFF Research Database (Denmark)

    Hansen, Anca Daniela; Margaris, Ioannis D.

    project to be incorporated in the wind power plant level. This document describes the Type 4 wind turbine simulation model, implemented in the EaseWind project. The implemented wind turbine model is one of the initial necessary steps toward integrating new control services in the wind power plant level....... In the project, this wind turbine model will be further incorporated in a wind power plant model together with the implementation in the wind power control level of the new control functionalities (inertial response, synchronising power and power system damping). For this purpose an aggregate wind power plant...... (WPP) will be considered. The aggregate WPP model, which will be based on the upscaling of the individual wind turbine model on the electrical part, will make use of an equivalent wind speed. The implemented model follows the basic structure of the generic standard Type 4 wind turbine model proposed...

  1. Atmospheric photochemistry of aromatic hydrocarbons: Analysis of OH budgets during SAPHIR chamber experiments and evaluation of MCMv3.2

    Science.gov (United States)

    Nehr, S.; Bohn, B.; Brauers, T.; Dorn, H.; Fuchs, H.; Häseler, R.; Hofzumahaus, A.; Li, X.; Lu, K.; Rohrer, F.; Tillmann, R.; Wahner, A.

    2012-12-01

    Aromatic hydrocarbons, almost exclusively originating from anthropogenic sources, comprise a significant fraction of volatile organic compounds observed in urban air. The photo-oxidation of aromatics results in the formation of secondary pollutants and impacts air quality in cities, industrialized areas, and districts of dense traffic. Up-to-date photochemical oxidation schemes of the Master Chemical Mechanism (MCMv3.2) exhibit moderate performance in simulating aromatic compound degradation observed during previous environmental chamber studies. To obtain a better understanding of aromatic photo-oxidation mechanisms, we performed experiments with a number of aromatic hydrocarbons in the outdoor atmosphere simulation chamber SAPHIR located in Jülich, Germany. These chamber studies were designed to derive OH turnover rates exclusively based on experimental data. Simultaneous measurements of NOx (= NO + NO2), HOx (= OH + HO2), and the total OH loss rate constant k(OH) facilitate a detailed analysis of the OH budgets during photo-oxidation experiments. The OH budget analysis was complemented by numerical model simulations using MCMv3.2. Despite MCM's tendency to overestimate k(OH) and to underpredict radical concentrations, the OH budgets are reasonably balanced for all investigated aromatics. However, the results leave some scope for OH producing pathways that are not considered in the current MCMv3.2. An improved reaction mechanism, derived from MCMv3.2 sensitivity studies, is presented. The model performance is basically improved by changes of the mechanistic representation of ring fragmentation channels.

  2. OH regeneration from methacrolein oxidation investigated in the atmosphere simulation chamber SAPHIR

    Science.gov (United States)

    Fuchs, H.; Acir, I.-H.; Bohn, B.; Brauers, T.; Dorn, H.-P.; Häseler, R.; Hofzumahaus, A.; Holland, F.; Kaminski, M.; Li, X.; Lu, K.; Lutz, A.; Nehr, S.; Rohrer, F.; Tillmann, R.; Wegener, R.; Wahner, A.

    2014-08-01

    Hydroxyl radicals (OH) are the most important reagent for the oxidation of trace gases in the atmosphere. OH concentrations measured during recent field campaigns in isoprene-rich environments were unexpectedly large. A number of studies showed that unimolecular reactions of organic peroxy radicals (RO2) formed in the initial reaction step of isoprene with OH play an important role for the OH budget in the atmosphere at low mixing ratios of nitrogen monoxide (NO) of less than 100 pptv. It has also been suggested that similar reactions potentially play an important role for RO2 from other compounds. Here, we investigate the oxidation of methacrolein (MACR), one major oxidation product of isoprene, by OH in experiments in the simulation chamber SAPHIR under controlled atmospheric conditions. The experiments show that measured OH concentrations are approximately 50% larger than calculated by the Master Chemical Mechanism (MCM) for conditions of the experiments (NO mixing ratio of 90 pptv). The analysis of the OH budget reveals an OH source that is not accounted for in MCM, which is correlated with the production rate of RO2 radicals from MACR. In order to balance the measured OH destruction rate, 0.77 OH radicals (1σ error: ± 0.31) need to be additionally reformed from each reaction of OH with MACR. The strong correlation of the missing OH source with the production of RO2 radicals is consistent with the concept of OH formation from unimolecular isomerization and decomposition reactions of RO2. The comparison of observations with model calculations gives a lower limit of 0.03 s-1 for the reaction rate constant if the OH source is attributed to an isomerization reaction of MACR-1-OH-2-OO and MACR-2-OH-2-OO formed in the MACR + OH reaction as suggested in the literature (Crounse et al., 2012). This fast isomerization reaction would be a competitor to the reaction of this RO2 species with a minimum of 150 pptv NO. The isomerization reaction would be the dominant

  3. Independent Verification and Validation Of SAPHIRE 8 Software Requirements Project Number: N6423 U.S. Nuclear Regulatory Commission

    Energy Technology Data Exchange (ETDEWEB)

    Kent Norris

    2009-09-01

    The purpose of the Independent Verification and Validation (IV&V) role in the evaluation of the SAPHIRE requirements definition is to assess the activities that results in the specification, documentation, and review of the requirements that the software product must satisfy, including functionality, performance, design constraints, attributes and external interfaces. The IV&V team began this endeavor after the software engineering and software development of SAPHIRE had already been in production. IV&V reviewed the requirements specified in the NRC Form 189s to verify these requirements were included in SAPHIRE’s Software Verification and Validation Plan (SVVP).

  4. Independent Verification and Validation Of SAPHIRE 8 Software Requirements Project Number: N6423 U.S. Nuclear Regulatory Commission

    Energy Technology Data Exchange (ETDEWEB)

    Kent Norris

    2010-03-01

    The purpose of the Independent Verification and Validation (IV&V) role in the evaluation of the SAPHIRE requirements definition is to assess the activities that results in the specification, documentation, and review of the requirements that the software product must satisfy, including functionality, performance, design constraints, attributes and external interfaces. The IV&V team began this endeavor after the software engineering and software development of SAPHIRE had already been in production. IV&V reviewed the requirements specified in the NRC Form 189s to verify these requirements were included in SAPHIRE’s Software Verification and Validation Plan (SVVP).

  5. Instream Physical Habitat Modelling Types

    DEFF Research Database (Denmark)

    Conallin, John; Boegh, Eva; Krogsgaard, Jørgen

    2010-01-01

    management tools, but require large amounts of data and the model structure is complex. It is concluded that the use of habitat suitability indices (HSIs) and fuzzy rules in hydraulic-habitat modelling are the most ready model types to satisfy WFD demands. These models are well documented, transferable, user-friendly...... and disadvantages as management tools for member states in relation to the requirements of the WFD, but due to their different model structures they are distinct in their data needs, transferability, user-friendliness and presentable outputs. Water resource managers need information on what approaches will best...

  6. A new plant chamber facility, PLUS, coupled to the atmosphere simulation chamber SAPHIR

    Science.gov (United States)

    Hohaus, T.; Kuhn, U.; Andres, S.; Kaminski, M.; Rohrer, F.; Tillmann, R.; Wahner, A.; Wegener, R.; Yu, Z.; Kiendler-Scharr, A.

    2016-03-01

    A new PLant chamber Unit for Simulation (PLUS) for use with the atmosphere simulation chamber SAPHIR (Simulation of Atmospheric PHotochemistry In a large Reaction Chamber) has been built and characterized at the Forschungszentrum Jülich GmbH, Germany. The PLUS chamber is an environmentally controlled flow-through plant chamber. Inside PLUS the natural blend of biogenic emissions of trees is mixed with synthetic air and transferred to the SAPHIR chamber, where the atmospheric chemistry and the impact of biogenic volatile organic compounds (BVOCs) can be studied in detail. In PLUS all important environmental parameters (e.g., temperature, photosynthetically active radiation (PAR), soil relative humidity (RH)) are well controlled. The gas exchange volume of 9.32 m3 which encloses the stem and the leaves of the plants is constructed such that gases are exposed to only fluorinated ethylene propylene (FEP) Teflon film and other Teflon surfaces to minimize any potential losses of BVOCs in the chamber. Solar radiation is simulated using 15 light-emitting diode (LED) panels, which have an emission strength up to 800 µmol m-2 s-1. Results of the initial characterization experiments are presented in detail. Background concentrations, mixing inside the gas exchange volume, and transfer rate of volatile organic compounds (VOCs) through PLUS under different humidity conditions are explored. Typical plant characteristics such as light- and temperature- dependent BVOC emissions are studied using six Quercus ilex trees and compared to previous studies. Results of an initial ozonolysis experiment of BVOC emissions from Quercus ilex at typical atmospheric concentrations inside SAPHIR are presented to demonstrate a typical experimental setup and the utility of the newly added plant chamber.

  7. A new plant chamber facility PLUS coupled to the atmospheric simulation chamber SAPHIR

    Science.gov (United States)

    Hohaus, T.; Kuhn, U.; Andres, S.; Kaminski, M.; Rohrer, F.; Tillmann, R.; Wahner, A.; Wegener, R.; Yu, Z.; Kiendler-Scharr, A.

    2015-11-01

    A new PLant chamber Unit for Simulation (PLUS) for use with the atmosphere simulation chamber SAPHIR (Simulation of Atmospheric PHotochemistry In a large Reaction Chamber) has been build and characterized at the Forschungszentrum Jülich GmbH, Germany. The PLUS chamber is an environmentally controlled flow through plant chamber. Inside PLUS the natural blend of biogenic emissions of trees are mixed with synthetic air and are transferred to the SAPHIR chamber where the atmospheric chemistry and the impact of biogenic volatile organic compounds (BVOC) can be studied in detail. In PLUS all important enviromental parameters (e.g. temperature, PAR, soil RH etc.) are well-controlled. The gas exchange volume of 9.32 m3 which encloses the stem and the leafes of the plants is constructed such that gases are exposed to FEP Teflon film and other Teflon surfaces only to minimize any potential losses of BVOCs in the chamber. Solar radiation is simulated using 15 LED panels which have an emission strength up to 800 μmol m-2 s-1. Results of the initial characterization experiments are presented in detail. Background concentrations, mixing inside the gas exchange volume, and transfer rate of volatile organic compounds (VOC) through PLUS under different humidity conditions are explored. Typical plant characteristics such as light and temperature dependent BVOC emissions are studied using six Quercus Ilex trees and compared to previous studies. Results of an initial ozonolysis experiment of BVOC emissions from Quercus Ilex at typical atmospheric concentrations inside SAPHIR are presented to demonstrate a typical experimental set up and the utility of the newly added plant chamber.

  8. Instream Physical Habitat Modelling Types

    DEFF Research Database (Denmark)

    Conallin, John; Boegh, Eva; Krogsgaard, Jørgen

    2010-01-01

    -friendly and have flexible data needs. They can easily be implemented in new regions using expert information or different types of local data. Furthermore, they are easily presentable to stakeholders and have the potential to be applied over large spatial scales. Integral care must be taken in the use...... and disadvantages as management tools for member states in relation to the requirements of the WFD, but due to their different model structures they are distinct in their data needs, transferability, user-friendliness and presentable outputs. Water resource managers need information on what approaches will best...... management tools, but require large amounts of data and the model structure is complex. It is concluded that the use of habitat suitability indices (HSIs) and fuzzy rules in hydraulic-habitat modelling are the most ready model types to satisfy WFD demands. These models are well documented, transferable, user...

  9. Independent Verification and Validation Of SAPHIRE 8 Software Configuration Management Plan Project Number: N6423 U.S. Nuclear Regulatory Commission

    Energy Technology Data Exchange (ETDEWEB)

    Kent Norris

    2009-10-01

    The purpose of the Independent Verification and Validation (IV&V) role in the evaluation of the SAPHIRE configuration management is to assess the activities that results in the process of identifying and defining the baselines associated with the SAPHIRE software product; controlling the changes to baselines and release of baselines throughout the life cycle; recording and reporting the status of baselines and the proposed and actual changes to the baselines; and verifying the correctness and completeness of baselines.. The IV&V team began this endeavor after the software engineering and software development of SAPHIRE had already been in production.

  10. Independent Verification and Validation Of SAPHIRE 8 Software Configuration Management Plan Project Number: N6423 U.S. Nuclear Regulatory Commission

    Energy Technology Data Exchange (ETDEWEB)

    Kent Norris

    2010-02-01

    The purpose of the Independent Verification and Validation (IV&V) role in the evaluation of the SAPHIRE configuration management is to assess the activities that results in the process of identifying and defining the baselines associated with the SAPHIRE software product; controlling the changes to baselines and release of baselines throughout the life cycle; recording and reporting the status of baselines and the proposed and actual changes to the baselines; and verifying the correctness and completeness of baselines.. The IV&V team began this endeavor after the software engineering and software development of SAPHIRE had already been in production.

  11. Independent Verification and Validation Of SAPHIRE 8 Risk Management Project Number: N6423 U.S. Nuclear Regulatory Commission

    Energy Technology Data Exchange (ETDEWEB)

    Kent Norris

    2009-11-01

    This report provides an evaluation of the risk management. Risk management is intended to ensure a methodology for conducting risk management planning, identification, analysis, responses, and monitoring and control activities associated with the SAPHIRE project work, and to meet the contractual commitments prepared by the sponsor; the Nuclear Regulatory Commission.

  12. Isotope effect in the formation of H2 from H2CO studied at the atmospheric simulation chamber SAPHIR

    NARCIS (Netherlands)

    Röckmann, T.; Walter, S.; Bohn, B.; Wegener, R.; Spahn, H.; Brauers, T.; Tillmann, R.; Schlosser, E.; Koppmann, R.; Rohrer, F.

    2010-01-01

    Formaldehyde of known, near-natural isotopic composition was photolyzed in the SAPHIR atmosphere simulation chamber under ambient conditions. The isotopic composition of the product H2 was used to determine the isotope effects in formaldehyde photolysis. The experiments are sensitive to the molecula

  13. Independent Verification and Validation Of SAPHIRE 8 Volume 3 Users' Guide Project Number: N6423 U.S. Nuclear Regulatory Commission

    Energy Technology Data Exchange (ETDEWEB)

    Kent Norris

    2010-03-01

    The purpose of the Independent Verification and Validation (IV&V) role in the evaluation of the SAPHIRE 8 Volume 3 Users’ Guide is to assess the user documentation for its completeness, correctness, and consistency with respect to requirements for user interface and for any functionality that can be invoked by the user. The IV&V team began this endeavor after the software engineering and software development of SAPHIRE had already been in production.

  14. Observation of the positive-strangeness pentaquark $\\Theta^+$ in photoproduction with the SAPHIR detector at ELSA

    CERN Document Server

    Barth, J; Ernst, J; Glander, K H; Hannappel, J; Jöpen, N; Kalinowsky, H; Klein, F; Klempt, E; Lawall, R; Link, J; Menze, D W; Neuerburg, W; Ostrick, M; Paul, E; Van Pee, H; Schulday, I; Schwille, W J; Wiegers, B; Wieland, F W; Wisskirchen, J; Wu, C

    2003-01-01

    The positive--strangeness baryon resonance $\\Theta^+$ is observed in photoproduction of the $\\rm nK^+K^0_s$ final state with the SAPHIR detector at the Bonn ELectron Stretcher Accelerator ELSA. It is seen as a peak in the $\\rm nK^+$ invariant mass distribution with a $4.8\\sigma$ confidence level. We find a mass $\\rm M_{\\Theta^+} = 1540\\pm 4\\pm 2$ MeV and an upper limit of the width $\\rm \\Gamma_{\\Theta^+} < 25$ MeV at 90% c.l. The photoproduction cross section for $\\rm\\bar K^0\\Theta^+$ is in the order of 300 nb. From the absence of a signal in the $\\rm pK^+$ invariant mass distribution in $\\rm\\gamma p\\to pK^+K^-$ at the expected strength we conclude that the $\\Theta^+$ must be isoscalar.

  15. Comparison of OH concentration measurements by DOAS and LIF during SAPHIR chamber experiments at high OH reactivity and low NO concentration

    Directory of Open Access Journals (Sweden)

    H. Fuchs

    2012-07-01

    Full Text Available During recent field campaigns, hydroxyl radical (OH concentrations that were measured by laser-induced fluorescence (LIF were up to a factor of ten larger than predicted by current chemical models for conditions of high OH reactivity and low NO concentration. These discrepancies, which were observed in forests and urban-influenced rural environments, are so far not entirely understood. In summer 2011, a series of experiments was carried out in the atmosphere simulation chamber SAPHIR in Jülich, Germany, in order to investigate the photochemical degradation of isoprene, methyl-vinyl ketone (MVK, methacrolein (MACR and aromatic compounds by OH. Conditions were similar to those experienced during the PRIDE-PRD2006 campaign in the Pearl River Delta (PRD, China, in 2006, where a large difference between OH measurements and model predictions was found. During experiments in SAPHIR, OH was simultaneously detected by two independent instruments: LIF and differential optical absorption spectroscopy (DOAS. Because DOAS is an inherently calibration-free technique, DOAS measurements are regarded as a reference standard. The comparison of the two techniques was used to investigate potential artifacts in the LIF measurements for PRD-like conditions of OH reactivities of 10 to 30 s−1 and NO mixing ratios of 0.1 to 0.3 ppbv. The analysis of twenty experiment days shows good agreement. The linear regression of the combined data set (averaged to the DOAS time resolution, 2495 data points yields a slope of 1.02 ± 0.01 with an intercept of (0.10 ± 0.03 × 106 cm−3 and a linear correlation coefficient of R2 = 0.86. This indicates that the sensitivity of the LIF instrument is well-defined by its calibration procedure. No hints for artifacts are observed for isoprene, MACR, and different aromatic compounds. LIF measurements were approximately 30–40% (median larger than those by DOAS after MVK (20 ppbv and

  16. Comparison of OH concentration measurements by DOAS and LIF during SAPHIR chamber experiments at high OH reactivity and low NO concentration

    Science.gov (United States)

    Fuchs, H.; Dorn, H.-P.; Bachner, M.; Bohn, B.; Brauers, T.; Gomm, S.; Hofzumahaus, A.; Holland, F.; Nehr, S.; Rohrer, F.; Tillmann, R.; Wahner, A.

    2012-07-01

    During recent field campaigns, hydroxyl radical (OH) concentrations that were measured by laser-induced fluorescence (LIF) were up to a factor of ten larger than predicted by current chemical models for conditions of high OH reactivity and low NO concentration. These discrepancies, which were observed in forests and urban-influenced rural environments, are so far not entirely understood. In summer 2011, a series of experiments was carried out in the atmosphere simulation chamber SAPHIR in Jülich, Germany, in order to investigate the photochemical degradation of isoprene, methyl-vinyl ketone (MVK), methacrolein (MACR) and aromatic compounds by OH. Conditions were similar to those experienced during the PRIDE-PRD2006 campaign in the Pearl River Delta (PRD), China, in 2006, where a large difference between OH measurements and model predictions was found. During experiments in SAPHIR, OH was simultaneously detected by two independent instruments: LIF and differential optical absorption spectroscopy (DOAS). Because DOAS is an inherently calibration-free technique, DOAS measurements are regarded as a reference standard. The comparison of the two techniques was used to investigate potential artifacts in the LIF measurements for PRD-like conditions of OH reactivities of 10 to 30 s-1 and NO mixing ratios of 0.1 to 0.3 ppbv. The analysis of twenty experiment days shows good agreement. The linear regression of the combined data set (averaged to the DOAS time resolution, 2495 data points) yields a slope of 1.02 ± 0.01 with an intercept of (0.10 ± 0.03) × 106 cm-3 and a linear correlation coefficient of R2 = 0.86. This indicates that the sensitivity of the LIF instrument is well-defined by its calibration procedure. No hints for artifacts are observed for isoprene, MACR, and different aromatic compounds. LIF measurements were approximately 30-40% (median) larger than those by DOAS after MVK (20 ppbv) and toluene (90 ppbv) had been added. However, this discrepancy has a

  17. Type-2 fuzzy granular models

    CERN Document Server

    Sanchez, Mauricio A; Castro, Juan R

    2017-01-01

    In this book, a series of granular algorithms are proposed. A nature inspired granular algorithm based on Newtonian gravitational forces is proposed. A series of methods for the formation of higher-type information granules represented by Interval Type-2 Fuzzy Sets are also shown, via multiple approaches, such as Coefficient of Variation, principle of justifiable granularity, uncertainty-based information concept, and numerical evidence based. And a fuzzy granular application comparison is given as to demonstrate the differences in how uncertainty affects the performance of fuzzy information granules.

  18. Total OH reactivity study from VOC photochemical oxidation in the SAPHIR chamber

    Science.gov (United States)

    Yu, Z.; Tillmann, R.; Hohaus, T.; Fuchs, H.; Novelli, A.; Wegener, R.; Kaminski, M.; Schmitt, S. H.; Wahner, A.; Kiendler-Scharr, A.

    2015-12-01

    It is well known that hydroxyl radicals (OH) act as a dominant reactive species in the degradation of VOCs in the atmosphere. In recent field studies, directly measured total OH reactivity often showed poor agreement with OH reactivity calculated from VOC measurements (e.g. Nölscher et al., 2013; Lu et al., 2012a). This "missing OH reactivity" is attributed to unaccounted biogenic VOC emissions and/or oxidation products. The comparison of total OH reactivity being directly measured and calculated from single component measurements of VOCs and their oxidation products gives us a further understanding on the source of unmeasured reactive species in the atmosphere. This allows also the determination of the magnitude of the contribution of primary VOC emissions and their oxidation products to the missing OH reactivity. A series of experiments was carried out in the atmosphere simulation chamber SAPHIR in Jülich, Germany, to explore in detail the photochemical degradation of VOCs (isoprene, ß-pinene, limonene, and D6-benzene) by OH. The total OH reactivity was determined from the measurement of VOCs and their oxidation products by a Proton Transfer Reaction Time of Flight Mass Spectrometer (PTR-TOF-MS) with a GC/MS/FID system, and directly measured by a laser-induced fluorescence (LIF) at the same time. The comparison between these two total OH reactivity measurements showed an increase of missing OH reactivity in the presence of oxidation products of VOCs, indicating a strong contribution to missing OH reactivity from uncharacterized oxidation products.

  19. Impact of horizontal and vertical localization scales on microwave sounder SAPHIR radiance assimilation

    Science.gov (United States)

    Krishnamoorthy, C.; Balaji, C.

    2016-05-01

    In the present study, the effect of horizontal and vertical localization scales on the assimilation of direct SAPHIR radiances is studied. An Artificial Neural Network (ANN) has been used as a surrogate for the forward radiative calculations. The training input dataset for ANN consists of vertical layers of atmospheric pressure, temperature, relative humidity and other hydrometeor profiles with 6 channel Brightness Temperatures (BTs) as output. The best neural network architecture has been arrived at, by a neuron independence study. Since vertical localization of radiance data requires weighting functions, a ANN has been trained for this purpose. The radiances were ingested into the NWP using the Ensemble Kalman Filter (EnKF) technique. The horizontal localization has been taken care of, by using a Gaussian localization function centered around the observed coordinates. Similarly, the vertical localization is accomplished by assuming a function which depends on the weighting function of the channel to be assimilated. The effect of both horizontal and vertical localizations has been studied in terms of ensemble spread in the precipitation. Aditionally, improvements in 24 hr forecast from assimilation are also reported.

  20. Comparison of OH reactivity instruments in the atmosphere simulation chamber SAPHIR

    Science.gov (United States)

    Fuchs, Hendrik

    2016-04-01

    OH reactivity measurement has become an important measurement to constrain the total OH loss frequency in field experiments. Different techniques have been developed by various groups. They can be based on flow-tube or pump and probe techniques, which include direct OH detection by fluorescence, or on a comparative method, in which the OH loss of a reference species competes with the OH loss of trace gases in the sampled air. In order to ensure that these techniques deliver equivalent results, a comparison exercise was performed under controlled conditions. Nine OH reactivity instruments measured together in the atmosphere simulation chamber SAPHIR (volume 270 m3) during ten daylong experiments in October 2015 at ambient temperature (5 to 10° C) and pressure (990-1010 hPa). The chemical complexity of air mixtures in these experiments varied from CO in pure synthetic air to emissions from real plants and VOC/NOx mixtures representative of urban atmospheres. Potential differences between measurements were systematically investigated by changing the amount of reactants (including isoprene, monoterpenes and sesquiterpenes), water vapour, and nitrogen oxides. Some of the experiments also included the oxidation of reactants with ozone or hydroxyl radicals, in order to elaborate, if the presence of oxidation products leads to systematic differences between measurements of different instruments. Here we present first results of this comparison exercise.

  1. 雷肯Saphir-7系列播种机

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    雷肯Saphir-7系列播种机,是同大型拖拉机配套使用的机械传动播种机械。该机悬挂于拖拉机后进行播种作业,利用3点悬挂及机前控制装置调节播种深度,适用于大面积浅耕麦类播种作业。主要特点:可选装单、双圆盘开沟器及锄齿式开沟器,对土地适应性强:采用播种计量轮及油浴式齿轮箱,无级调节播种量,播量准确、节省种子;可与驱动耙或耕耘机具组成机组进行复式作业。

  2. Relative humidity distribution from SAPHIR experiment on board Megha-Tropiques satellite mission: Comparison with global radiosonde and other satellite and reanalysis data sets

    Science.gov (United States)

    Venkat Ratnam, M.; Basha, Ghouse; Krishna Murthy, B. V.; Jayaraman, A.

    2013-09-01

    For better understanding the life cycle of the convective systems and their interactions with the environment, a joint Indo-French satellite mission named Megha-Tropiques has been launched in October 2011 in a low-inclination (20°) orbit. In the present study, we show the first results on the comparison of relative humidity (RH) obtained using a six-channel microwave sounder, covering from surface to 100 hPa, from one of the payloads SAPHIR (Sounder for Atmospheric Profiling of Humidity in the Inter-tropical Regions). The RH observations from SAPHIR illustrated the numerous scales of variability in the atmosphere both vertically and horizontally. As a part of its validation, we compare SAPHIR RH with simultaneous observations from a network of radiosondes distributed across the world (±30° latitude), other satellites (Atmospheric Infrared Sounder, Infrared Atmospheric Sounder Interferometer, Constellation Observation System for Meteorology Ionosphere and Climate (COSMIC)), and various reanalysis (National Center for Environmental Prediction (NCEP), European Center for Medium-Range Weather Forecasts reanalysis (ERA)-Interim, Modern-Era Retrospective Analysis for Research and Application (MERRA)) products. Being at a low inclination, SAPHIR is able to show better global coverage when compared to any other existing satellites in the tropical region where some important weather processes take place. A very good correlation is noticed with the RH obtained from a global radiosonde network particularly in the altitude range corresponding to 850-250 hPa, thus providing a valuable data set for investigating the convective processes. In the case of satellite data sets, SAPHIR RH is well comparable with COSMIC RH. Among the reanalysis products, NCEP shows less difference with SAPHIR followed by ERA-Interim, and the MERRA products show large differences in the middle and upper troposphere.

  3. Theoretical models for Type I and Type II supernova

    Energy Technology Data Exchange (ETDEWEB)

    Woosley, S.E.; Weaver, T.A.

    1985-01-01

    Recent theoretical progress in understanding the origin and nature of Type I and Type II supernovae is discussed. New Type II presupernova models characterized by a variety of iron core masses at the time of collapse are presented and the sensitivity to the reaction rate /sup 12/C(..cap alpha..,..gamma..)/sup 16/O explained. Stars heavier than about 20 M/sub solar/ must explode by a ''delayed'' mechanism not directly related to the hydrodynamical core bounce and a subset is likely to leave black hole remnants. The isotopic nucleosynthesis expected from these massive stellar explosions is in striking agreement with the sun. Type I supernovae result when an accreting white dwarf undergoes a thermonuclear explosion. The critical role of the velocity of the deflagration front in determining the light curve, spectrum, and, especially, isotopic nucleosynthesis in these models is explored. 76 refs., 8 figs.

  4. Independent Verification and Validation Of SAPHIRE 8 Software Design and Interface Design Project Number: N6423 U.S. Nuclear Regulatory Commission

    Energy Technology Data Exchange (ETDEWEB)

    Kent Norris

    2009-10-01

    The purpose of the Independent Verification and Validation (IV&V) role in the evaluation of the SAPHIRE software design and interface design is to assess the activities that results in the development, documentation, and review of a software design that meets the requirements defined in the software requirements documentation. The IV&V team began this endeavor after the software engineering and software development of SAPHIRE had already been in production. IV&V reviewed the requirements specified in the NRC Form 189s to verify these requirements were included in SAPHIRE’s Software Verification and Validation Plan (SVVP) design specification.

  5. Independent Verification and Validation Of SAPHIRE 8 Software Acceptance Test Plan Project Number: N6423 U.S. Nuclear Regulatory Commission

    Energy Technology Data Exchange (ETDEWEB)

    Kent Norris

    2010-03-01

    The purpose of the Independent Verification and Validation (IV&V) role in the evaluation of the SAPHIRE 8 Software Acceptance Test Plan is to assess the approach to be taken for intended testing activities. The plan typically identifies the items to be tested, the requirements being tested, the testing to be performed, test schedules, personnel requirements, reporting requirements, evaluation criteria, and any risks requiring contingency planning. The IV&V team began this endeavor after the software engineering and software development of SAPHIRE had already been in production.

  6. Independent Verification and Validation Of SAPHIRE 8 Software Design and Interface Design Project Number: N6423 U.S. Nuclear Regulatory Commission

    Energy Technology Data Exchange (ETDEWEB)

    Kent Norris

    2010-03-01

    The purpose of the Independent Verification and Validation (IV&V) role in the evaluation of the SAPHIRE software design and interface design is to assess the activities that results in the development, documentation, and review of a software design that meets the requirements defined in the software requirements documentation. The IV&V team began this endeavor after the software engineering and software development of SAPHIRE had already been in production. IV&V reviewed the requirements specified in the NRC Form 189s to verify these requirements were included in SAPHIRE’s Software Verification and Validation Plan (SVVP) design specification.

  7. A Type Graph Model for Java Programs

    NARCIS (Netherlands)

    Rensink, Arend; Zambon, Eduardo

    2009-01-01

    In this report we present a type graph that models all executable constructs of the Java programming language. Such a model is useful for any graph-based technique that relies on a representation of Java programs as graphs. The model can be regarded as a common representation to which all Java

  8. A Type Graph Model for Java Programs

    NARCIS (Netherlands)

    Rensink, Arend; Zambon, Eduardo; Lee, D.; Lopes, A.; Poetzsch-Heffter, A.

    2009-01-01

    In this work we present a type graph that models all executable constructs of the Java programming language. Such a model is useful for any graph-based technique that relies on a representation of Java programs as graphs. The model can be regarded as a common representation to which all Java syntax

  9. A Type Graph Model for Java Programs

    NARCIS (Netherlands)

    Rensink, Arend; Zambon, Eduardo; Lee, D.; Lopes, A.; Poetzsch-Heffter, A.

    2009-01-01

    In this work we present a type graph that models all executable constructs of the Java programming language. Such a model is useful for any graph-based technique that relies on a representation of Java programs as graphs. The model can be regarded as a common representation to which all Java syntax

  10. A Type Graph Model for Java Programs

    NARCIS (Netherlands)

    Rensink, Arend; Zambon, Eduardo

    2009-01-01

    In this report we present a type graph that models all executable constructs of the Java programming language. Such a model is useful for any graph-based technique that relies on a representation of Java programs as graphs. The model can be regarded as a common representation to which all Java synta

  11. Topological and Simplicial Models of Identity Types

    NARCIS (Netherlands)

    van den Berg, B.; Garner, R.

    2012-01-01

    In this paper we construct new categorical models for the identity types of Martin-Löf type theory, in the categories Top of topological spaces and SSet of simplicial sets. We do so building on earlier work of Awodey and Warren [2009], which has suggested that a suitable environment for the interpre

  12. A Finite Model Property for Intersection Types

    Directory of Open Access Journals (Sweden)

    Rick Statman

    2015-03-01

    Full Text Available We show that the relational theory of intersection types known as BCD has the finite model property; that is, BCD is complete for its finite models. Our proof uses rewriting techniques which have as an immediate by-product the polynomial time decidability of the preorder <= (although this also follows from the so called beta soundness of BCD.

  13. A Matrix Model for Type 0 Strings

    CERN Document Server

    Peñalba, J P

    1999-01-01

    A matrix model for type 0 strings is proposed. It consists in making a non-supersymmetric orbifold projection in the Yang-Mills theory and identifying the infrared configurations of the system at infinite coupling with strings. The correct partition function is calculated. Also, the usual spectrum of branes is found. Both type A and B models are constructed. The model in a torus contains all the degrees of freedom and interpolates between the four string theories (IIA, IIB, 0A, 0B) and the M theory as different limits are taken.

  14. Spontaneous Type 2 Diabetic Rodent Models

    Science.gov (United States)

    Wang, Yang-wei; Sun, Guang-dong; Sun, Jing; Liu, Shu-jun; Wang, Ji; Xu, Xiao-hong; Miao, Li-ning

    2013-01-01

    Diabetes mellitus, especially type 2 diabetes (T2DM), is one of the most common chronic diseases and continues to increase in numbers with large proportion of health care budget being used. Many animal models have been established in order to investigate the mechanisms and pathophysiologic progress of T2DM and find effective treatments for its complications. On the basis of their strains, features, advantages, and disadvantages, various types of animal models of T2DM can be divided into spontaneously diabetic models, artificially induced diabetic models, and transgenic/knockout diabetic models. Among these models, the spontaneous rodent models are used more frequently because many of them can closely describe the characteristic features of T2DM, especially obesity and insulin resistance. In this paper, we aim to investigate the current available spontaneous rodent models for T2DM with regard to their characteristic features, advantages, and disadvantages, and especially to describe appropriate selection and usefulness of different spontaneous rodent models in testing of various new antidiabetic drugs for the treatment of type 2 diabetes. PMID:23671868

  15. Comparison of N2O5 mixing ratios during NO3Comp 2007 in SAPHIR

    Directory of Open Access Journals (Sweden)

    A. W. Rollins

    2012-07-01

    Full Text Available N2O5 detection in the atmosphere has been accomplished using techniques which have been developed during the last decade. Most techniques use a heated inlet to thermally decompose N2O5 to NO3, which can be detected by either cavity based absorption at 662 nm or by laser-induced fluorescence. In summer 2007, a large set of instruments, which were capable of measuring NO3 mixing ratios, were simultaneously deployed in the atmosphere simulation chamber SAPHIR in Jülich, Germany. Some of these instruments measured N2O5 mixing ratios either simultaneously or alternatively. Experiments focussed on the investigation of potential interferences from e.g. water vapor or aerosol and on the investigation of the oxidation of biogenic volatile organic compounds by NO3. The comparison of N2O5 mixing ratios shows an excellent agreement between measurements of instruments applying different techniques (3 cavity ring-down (CRDS instruments, 2 laser-induced fluorescence (LIF instruments. Data sets are highly correlated as indicated by the square of the linear correlation coefficients, R2, which values are larger than 0.96 for the entire data sets. N2O5 mixing ratios well agree within the combined accuracy of measurements. Slopes of the linear regression range between 0.87 and 1.26 and intercepts are negligible. The most critical aspect of N2O5 measurements by cavity ring-down instruments is the determination of the inlet and filter transmission efficiency. Measurements here show that the N2O5 inlet transmission efficiency can decrease in the presence of high aerosol loads, and that frequent filter/inlet changing is necessary to quantitatively sample N2O5 in some environments. The analysis of data also demonstrates that a general correction for degrading filter transmission is not applicable for all conditions encountered during this campaign. Besides the effect of a gradual degradation of the inlet transmission efficiency aerosol exposure, no other interference

  16. Comparison of N2O5 mixing ratios during NO3Comp 2007 in SAPHIR

    Science.gov (United States)

    Fuchs, H.; Simpson, W. R.; Apodaca, R. L.; Brauers, T.; Cohen, R. C.; Crowley, J. N.; Dorn, H.-P.; Dubé, W. P.; Fry, J. L.; Häseler, R.; Kajii, Y.; Kiendler-Scharr, A.; Labazan, I.; Matsumoto, J.; Mentel, T. F.; Nakashima, Y.; Rohrer, F.; Rollins, A. W.; Schuster, G.; Tillmann, R.; Wahner, A.; Wooldridge, P. J.; Brown, S. S.

    2012-11-01

    N2O5 detection in the atmosphere has been accomplished using techniques which have been developed during the last decade. Most techniques use a heated inlet to thermally decompose N2O5 to NO3, which can be detected by either cavity based absorption at 662 nm or by laser-induced fluorescence. In summer 2007, a large set of instruments, which were capable of measuring NO3 mixing ratios, were simultaneously deployed in the atmosphere simulation chamber SAPHIR in Jülich, Germany. Some of these instruments measured N2O5 mixing ratios either simultaneously or alternatively. Experiments focused on the investigation of potential interferences from, e.g., water vapour or aerosol and on the investigation of the oxidation of biogenic volatile organic compounds by NO3. The comparison of N2O5 mixing ratios shows an excellent agreement between measurements of instruments applying different techniques (3 cavity ring-down (CRDS) instruments, 2 laser-induced fluorescence (LIF) instruments). Datasets are highly correlated as indicated by the square of the linear correlation coefficients, R2, which values were larger than 0.96 for the entire datasets. N2O5 mixing ratios well agree within the combined accuracy of measurements. Slopes of the linear regression range between 0.87 and 1.26 and intercepts are negligible. The most critical aspect of N2O5 measurements by cavity ring-down instruments is the determination of the inlet and filter transmission efficiency. Measurements here show that the N2O5 inlet transmission efficiency can decrease in the presence of high aerosol loads, and that frequent filter/inlet changing is necessary to quantitatively sample N2O5 in some environments. The analysis of data also demonstrates that a general correction for degrading filter transmission is not applicable for all conditions encountered during this campaign. Besides the effect of a gradual degradation of the inlet transmission efficiency aerosol exposure, no other interference for N2O5

  17. Topological and simplicial models of identity types

    CERN Document Server

    Berg, Benno van den

    2010-01-01

    In this paper we construct new categorical models for the identity types of Martin-L\\"of type theory, in the categories Top of topological spaces and SSet of simplicial sets. We do so building on earlier work of Awodey and Warren, which has suggested that a suitable environment for the interpretation of identity types should be a category equipped with a weak factorisation system in the sense of Bousfield--Quillen. It turns out that this is not quite enough for a sound model, due to some subtle coherence issues concerned with stability under substitution; and so our first task is to introduce a slightly richer structure---which we call a homotopy-theoretic model of identity types---and to prove that this is sufficient for a sound interpretation. Now, although both Top and SSet are categories endowed with a weak factorisation system---and indeed, an entire Quillen model structure---exhibiting the additional structure required for a homotopy-theoretic model is quite hard to do. However, the categories we are in...

  18. Isotope effect in the formation of H2 from H2CO studied at the atmospheric simulation chamber SAPHIR

    Directory of Open Access Journals (Sweden)

    R. Koppmann

    2010-06-01

    Full Text Available Formaldehyde of known, near-natural isotopic composition was photolyzed in the SAPHIR atmosphere simulation chamber under ambient conditions. The isotopic composition of the product H2 was used to determine the isotope effects in formaldehyde photolysis. The experiments are sensitive to the molecular photolysis channel, and the radical channel has only an indirect effect and cannot be effectively constrained. The molecular channel kinetic isotope effect KIEmol, the ratio of photolysis frequencies j(HCHO→CO+H2/j(HCDO→CO+HD at surface pressure, is determined to be KIEmol=1.63−0.046+0.038. This is similar to the kinetic isotope effect for the total removal of HCHO from a recent relative rate experiment (KIEtot=1.58±0.03, which indicates that the KIEs in the molecular and radical photolysis channels at surface pressure (≈100 kPa may not be as different as described previously in the literature.

  19. Improvements to type Ia supernova models

    Science.gov (United States)

    Saunders, Clare M.

    Type Ia Supernovae provided the first strong evidence of dark energy and are still an important tool for measuring the accelerated expansion of the universe. However, future improvements will be limited by systematic uncertainties in our use of Type Ia supernovae as standard candles. Using Type Ia supernovae for cosmology relies on our ability to standardize their absolute magnitudes, but this relies on imperfect models of supernova spectra time series. This thesis is focused on using data from the Nearby Supernova Factory both to understand current sources of uncertainty in standardizing Type Ia supernovae and to develop techniques that can be used to limit uncertainty in future analyses. (Abstract shortened by ProQuest.).

  20. Secondary organic aerosols - formation and ageing studies in the SAPHIR chamber

    Science.gov (United States)

    Spindler, Christian; Müller, Lars; Trimborn, Achim; Mentel, Thomas; Hoffmann, Thorsten

    2010-05-01

    Secondary organic aerosol (SOA) formation from oxidation products of biogenic volatile organic compounds (BVOC) constitutes an important coupling between vegetation, atmospheric chemistry, and climate change. Such secondary organic aerosol components play an important role in particle formation in Boreal regions ((Laaksonen et al., 2008)), where biogenic secondary organic aerosols contribute to an overall negative radiative forcing, thus a negative feed back between vegetation and climate warming (Spracklen et al., 2008). Within the EUCAARI project we investigated SOA formation from mixtures of monoterpenes (and sesquiterpenes) as emitted typically from Boreal tree species in Southern Finland. The experiments were performed in the large photochemical reactor SAPHIR in Juelich at natural light and oxidant levels. Oxidation of the BVOC mixtures and SOA formation was induced by OH radicals and O3. The SOA was formed on the first day and then aged for another day. The resulting SOA was characterized by HR-ToF-AMS, APCI-MS, and filter samples with subsequent H-NMR, GC-MS and HPLC-MS analysis. The chemical evolution of the SOA is characterized by a fast increase of the O/C ratio during the formation process on the first day, stable O/C ratio during night, and a distinctive increase of O/C ratio at the second day. The increase of the O/C ratio on the second day is highly correlated to the OH dose and is accompanied by condensational growth of the particles. We will present simultaneous factor analysis of AMS times series (PMF, Ulbrich et al., 2009 ) and direct measurements of individual chemical species. We found that four factors were needed to represent the time evolution of the SOA composition (in the mass spectra) if oxidation by OH plays a mayor role. Corresponding to these factors we observed individual, representative molecules with very similar time behaviour. The correlation between tracers and AMS factors is astonishingly good as the molecular tracers

  1. Intercomparison of NO3 radical detection instruments in the atmosphere simulation chamber SAPHIR

    Directory of Open Access Journals (Sweden)

    J. Thieser

    2013-01-01

    Full Text Available The detection of atmospheric NO3 radicals is still challenging owing to its low mixing ratios (≈ 1 to 300 pptv in the troposphere. While long-path differential optical absorption spectroscopy (DOAS is a well established NO3 detection approach for over 25 yr, newly sensitive techniques have been developed in the past decade. This publication outlines the results of the first comprehensive intercomparison of seven instruments developed for the spectroscopic detection of tropospheric NO3. Four instruments were based on cavity ring-down spectroscopy (CRDS, two utilised open-path cavity enhanced absorption spectroscopy (CEAS, and one applied "classical" long-path DOAS. The intercomparison campaign "NO3Comp" was held at the atmosphere simulation chamber SAPHIR in Jülich (Germany in June 2007. Twelve experiments were performed in the well mixed chamber for variable concentrations of NO3, N2O5, NO2, hydrocarbons, and water vapour, in the absence and in the presence of inorganic or organic aerosol. The overall precision of the cavity instruments varied between 0.5 and 5 pptv for integration times of 1 s to 5 min; that of the DOAS instrument was 9 pptv for an acquisition time of 1 min. The NO3 data of all instruments correlated excellently with the NOAA-CRDS instrument, which was selected as the common reference because of its superb sensitivity, high time resolution, and most comprehensive data coverage. The median of the coefficient of determination (r2 over all experiments of the campaign (60 correlations is r2 = 0.981 (25th/75th percentiles: 0.949/0.994; min/max: 0.540/0.999. The linear regression analysis of the campaign data set yielded very small intercepts (1.2 ± 5.3 pptv and the average slope of the regression lines was close to unity (1.02, min: 0.72, max: 1.36. The deviation of individual regression slopes from unity was always within the combined accuracies of each instrument pair. The very good correspondence between the NO3 measurements

  2. Intercomparison of NO3 radical detection instruments in the atmosphere simulation chamber SAPHIR

    Directory of Open Access Journals (Sweden)

    H.-P. Dorn

    2013-05-01

    Full Text Available The detection of atmospheric NO3 radicals is still challenging owing to its low mixing ratios (≈ 1 to 300 pptv in the troposphere. While long-path differential optical absorption spectroscopy (DOAS has been a well-established NO3 detection approach for over 25 yr, newly sensitive techniques have been developed in the past decade. This publication outlines the results of the first comprehensive intercomparison of seven instruments developed for the spectroscopic detection of tropospheric NO3. Four instruments were based on cavity ring-down spectroscopy (CRDS, two utilised open-path cavity-enhanced absorption spectroscopy (CEAS, and one applied "classical" long-path DOAS. The intercomparison campaign "NO3Comp" was held at the atmosphere simulation chamber SAPHIR in Jülich (Germany in June 2007. Twelve experiments were performed in the well-mixed chamber for variable concentrations of NO3, N2O5, NO2, hydrocarbons, and water vapour, in the absence and in the presence of inorganic or organic aerosol. The overall precision of the cavity instruments varied between 0.5 and 5 pptv for integration times of 1 s to 5 min; that of the DOAS instrument was 9 pptv for an acquisition time of 1 min. The NO3 data of all instruments correlated excellently with the NOAA-CRDS instrument, which was selected as the common reference because of its superb sensitivity, high time resolution, and most comprehensive data coverage. The median of the coefficient of determination (r2 over all experiments of the campaign (60 correlations is r2 = 0.981 (quartile 1 (Q1: 0.949; quartile 3 (Q3: 0.994; min/max: 0.540/0.999. The linear regression analysis of the campaign data set yielded very small intercepts (median: 1.1 pptv; Q1/Q3: −1.1/2.6 pptv; min/max: −14.1/28.0 pptv, and the slopes of the regression lines were close to unity (median: 1.01; Q1/Q3: 0.92/1.10; min/max: 0.72/1.36. The deviation of individual regression slopes from unity was always within the combined

  3. Intercomparison of NO3 radical detection instruments in the atmosphere simulation chamber SAPHIR

    Science.gov (United States)

    Dorn, H.-P.; Apodaca, R. L.; Ball, S. M.; Brauers, T.; Brown, S. S.; Crowley, J. N.; Dubé, W. P.; Fuchs, H.; Häseler, R.; Heitmann, U.; Jones, R. L.; Kiendler-Scharr, A.; Labazan, I.; Langridge, J. M.; Meinen, J.; Mentel, T. F.; Platt, U.; Pöhler, D.; Rohrer, F.; Ruth, A. A.; Schlosser, E.; Schuster, G.; Shillings, A. J. L.; Simpson, W. R.; Thieser, J.; Tillmann, R.; Varma, R.; Venables, D. S.; Wahner, A.

    2013-05-01

    The detection of atmospheric NO3 radicals is still challenging owing to its low mixing ratios (≈ 1 to 300 pptv) in the troposphere. While long-path differential optical absorption spectroscopy (DOAS) has been a well-established NO3 detection approach for over 25 yr, newly sensitive techniques have been developed in the past decade. This publication outlines the results of the first comprehensive intercomparison of seven instruments developed for the spectroscopic detection of tropospheric NO3. Four instruments were based on cavity ring-down spectroscopy (CRDS), two utilised open-path cavity-enhanced absorption spectroscopy (CEAS), and one applied "classical" long-path DOAS. The intercomparison campaign "NO3Comp" was held at the atmosphere simulation chamber SAPHIR in Jülich (Germany) in June 2007. Twelve experiments were performed in the well-mixed chamber for variable concentrations of NO3, N2O5, NO2, hydrocarbons, and water vapour, in the absence and in the presence of inorganic or organic aerosol. The overall precision of the cavity instruments varied between 0.5 and 5 pptv for integration times of 1 s to 5 min; that of the DOAS instrument was 9 pptv for an acquisition time of 1 min. The NO3 data of all instruments correlated excellently with the NOAA-CRDS instrument, which was selected as the common reference because of its superb sensitivity, high time resolution, and most comprehensive data coverage. The median of the coefficient of determination (r2) over all experiments of the campaign (60 correlations) is r2 = 0.981 (quartile 1 (Q1): 0.949; quartile 3 (Q3): 0.994; min/max: 0.540/0.999). The linear regression analysis of the campaign data set yielded very small intercepts (median: 1.1 pptv; Q1/Q3: -1.1/2.6 pptv; min/max: -14.1/28.0 pptv), and the slopes of the regression lines were close to unity (median: 1.01; Q1/Q3: 0.92/1.10; min/max: 0.72/1.36). The deviation of individual regression slopes from unity was always within the combined accuracies of each

  4. Binary progenitor models of type IIb supernovae

    CERN Document Server

    Claeys, J S W; Pols, O R; Eldridge, J J; Baes, M

    2011-01-01

    Massive stars that lose their hydrogen-rich envelope down to a few tenths of a solar mass explode as extended type IIb supernovae, an intriguing subtype that links the hydrogen-rich type II supernovae with the hydrogen-poor type Ib and Ic. The progenitors may be very massive single stars that lose their envelope due to their stellar wind, but mass stripping due to interaction with a companion star in a binary system is currently considered to be the dominant formation channel. We computed an extensive grid of binary models with the Eggleton binary evolution code. The predicted rate from our standard models, which assume conservative mass transfer, is about 6 times smaller than the current rate indicated by observations. It is larger but still comparable to the rate expected from single stars. To recover the observed rate we must generously allow for uncertainties and low accretion efficiencies in combination with limited angular momentum loss from the system. Motivated by the claims of detection and non-detec...

  5. Strictly isospectral Bianchi type II cosmological models

    CERN Document Server

    Rosu, H C; Obregón, O

    1996-01-01

    We show that, in the Q=0 factor ordering, the Wheeler-DeWitt equation for the Bianchi type ll model with the Ansatz \\rm \\Psi=A\\, e^{\\pm \\Phi(q^{\\mu})}, due to its one-dimensional character, may be approached by the strictly isospectral Darboux-Witten technique in standard supersymmetric quantum mechanics. One-parameter families of cosmological potentials and normalizable `wavefunctions of the universe' are exhibited. The isospectral method can be used to introduce normalizable wavefunctions in quantum cosmology.

  6. OH Oxidation of α-Pinene in the Atmosphere Simulation Chamber SAPHIR: Investigation of the Role of Pinonaldehyde Photolysis as an HO2 Source

    Science.gov (United States)

    Kaminski, M.; Acir, I. H.; Bohn, B.; Dorn, H. P.; Fuchs, H.; Häseler, R.; Hofzumahaus, A.; Li, X.; Rohrer, F.; Tillmann, R.; Wegener, R.; Kiendler-Scharr, A.; Wahner, A.

    2015-12-01

    About one third of the land surface is covered by forests, emitting approximately 75% of the total biogenic volatile organic compounds (BVOCs). The main atmospheric sink of these BVOCs during daytime is the oxidation by the hydroxyl radical (OH). Over the last decades field campaigns investigating the radical chemistry in forested regions showed that atmospheric chemistry models are often not able to describe the measured OH concentration well. At low NO concentrations and an OH reactivity dominated by BVOCs the OH was underestimated. This discrepancy could only partly be explained by the discovery of new OH regeneration pathways in the isoprene oxidation mechanism. Field campaigns in the U.S.A and Finland (Kim 2013 ACP, Hens 2014 ACP) demonstrated that in monoterpene (e.g. α-pinene) dominated environments model calculations also underpredict the observed HO2 and OH concentrations significantly even if the OH budget was closed by the measured OH production and destruction terms. These observations suggest the existence of an unaccounted source of HO2. One potential HO2 source in forests is the photolysis of monoterpene degradation products such as aldehydes. In the present study the photochemical degradation mechanism of α-pinene was investigated in the Jülich atmosphere simulation chamber SAPHIR. The focus of this study was in particular on the investigation of the role of pinonaldehyde, a main first generation product of α-pinene, as a possible HO2 source. For that purpose the pinonaldehyde yields of the reaction α-pinene + OH were determined at ambient monoterpene concentrations (<5 ppb) under low NOx as well as high NOx conditions. The pinonaldehyde yield under high NOx conditions (30.5 %) is in agreement with literature values of Wisthaler (2001 AE) and Aschmann (2002 JGR), under low NOx conditions the yield (10.8 %) is approximately a factor of three lower than the value published by Eddingsaas (2012 ACP). In a second set of experiments the photolysis

  7. Fuzzy modelling for selecting headgear types.

    Science.gov (United States)

    Akçam, M Okan; Takada, Kenji

    2002-02-01

    The purpose of this study was to develop a computer-assisted inference model for selecting appropriate types of headgear appliance for orthodontic patients and to investigate its clinical versatility as a decision-making aid for inexperienced clinicians. Fuzzy rule bases were created for degrees of overjet, overbite, and mandibular plane angle variables, respectively, according to subjective criteria based on the clinical experience and knowledge of the authors. The rules were then transformed into membership functions and the geometric mean aggregation was performed to develop the inference model. The resultant fuzzy logic was then tested on 85 cases in which the patients had been diagnosed as requiring headgear appliances. Eight experienced orthodontists judged each of the cases, and decided if they 'agreed', 'accepted', or 'disagreed' with the recommendations of the computer system. Intra-examiner agreements were investigated using repeated judgements of a set of 30 orthodontic cases and the kappa statistic. All of the examiners exceeded a kappa score of 0.7, allowing them to participate in the test run of the validity of the proposed inference model. The examiners' agreement with the system's recommendations was evaluated statistically. The average satisfaction rate of the examiners was 95.6 per cent and, for 83 out of the 85 cases, 97.6 per cent. The majority of the examiners (i.e. six or more out of the eight) were satisfied with the recommendations of the system. Thus, the usefulness of the proposed inference logic was confirmed.

  8. Spectral modeling of Type II SNe

    Science.gov (United States)

    Dessart, Luc

    2015-08-01

    The red supergiant phase represents the final stage of evolution in the life of moderate mass (8-25Msun) massive stars. Hidden from view, the core changes considerably its structure, progressing through the advanced stages of nuclear burning, and eventually becomes degenerate. Upon reaching the Chandrasekhar mass, this Fe or ONeMg core collapses, leading to the formation of a proto neutron star. A type II supernova results if the shock that forms at core bounce, eventually wins over the envelope accretion and reaches the progenitor surface.The electromagnetic display of such core-collapse SNe starts with this shock breakout, and persists for months as the ejecta releases the energy deposited initially by the shock or continuously through radioactive decay. Over a timescale of weeks to months, the originally optically-thick ejecta thins out and turns nebular. SN radiation contains a wealth of information about the explosion physics (energy, explosive nucleosynthesis), the progenitor properties (structure and composition). Polarised radiation also offers signatures that can help constrain the morphology of the ejecta.In this talk, I will review the current status of type II SN spectral modelling, and emphasise that a proper solution requires a time dependent treatment of the radiative transfer problem. I will discuss the wealth of information that can be gleaned from spectra as well as light curves, from both the early times (photospheric phase) and late times (nebular phase). I will discuss the diversity of Type SNe properties and how they are related to the diversity of red supergiant stars from which they originate.SN radiation offers an alternate means of constraining the properties of red-supergiant stars. To wrap up, I will illustrate how SNe II-P can also be used as probes, for example to constrain the metallicity of their environment.

  9. Intercomparison of measurements of NO2 concentrations in the atmosphere simulation chamber SAPHIR during the NO3Comp campaign

    Directory of Open Access Journals (Sweden)

    H. Fuchs

    2010-01-01

    Full Text Available NO2 concentrations were measured by various instruments during the NO3Comp campaign at the atmosphere simulation chamber SAPHIR at Forschungszentrum Jülich, Germany, in June 2007. Analytical methods included photolytic conversion with chemiluminescence (PC-CLD, broadband cavity ring-down spectroscopy (BBCRDS, pulsed cavity ring-down spectroscopy (CRDS, incoherent broadband cavity-enhanced absorption spectroscopy (IBB\\-CEAS, and laser-induced fluorescence (LIF. All broadband absorption spectrometers were optimized for the detection of the main target species of the campaign, NO3, but were also capable of detecting NO2 simultaneously with reduced sensitivity. NO2 mixing ratios in the chamber were within a range characteristic of polluted, urban conditions, with a maximum mixing ratio of approximately 75 ppbv. The overall agreement between measurements of all instruments was excellent. Linear fits of the combined data sets resulted in slopes that differ from unity only within the stated uncertainty of each instrument. Possible interferences from species such as water vapor and ozone were negligible under the experimental conditions.

  10. Intercomparison of measurements of NO2 concentrations in the atmosphere simulation chamber SAPHIR during the NO3Comp campaign

    Directory of Open Access Journals (Sweden)

    R. M. Varma

    2009-10-01

    Full Text Available NO2 concentrations were measured by various instruments during the NO3Comp campaign at the atmosphere simulation chamber SAPHIR at Forschungszentrum Jülich, Germany, in June 2007. Analytic methods included photolytic conversion with chemiluminescence (PC-CLD, broadband cavity ring-down spectroscopy (BBCRDS, pulsed cavity ring-down spectroscopy (CRDS, incoherent broadband cavity-enhanced absorption spectroscopy (IBBCEAS, and laser-induced fluorescence (LIF. All broadband absorption spectrometers were optimized for the detection of the main target species of the campaign, NO2, but were also capable of detecting NO2 simultaneously with reduced sensitivity. NO2 mixing ratios in the chamber were within a range characteristic of polluted, urban conditions, with a maximum mixing ratio of approximately 75 ppbv. The overall agreement between measurements of all instruments was excellent. Linear fits of the combined data sets resulted in slopes that differ from unity only within the stated uncertainty of each instrument. Possible interferences from species such as water vapor and ozone were negligible under the experimental conditions.

  11. A Typed Model for Dynamic Authorizations

    Directory of Open Access Journals (Sweden)

    Silvia Ghilezan

    2016-02-01

    Full Text Available Security requirements in distributed software systems are inherently dynamic. In the case of authorization policies, resources are meant to be accessed only by authorized parties, but the authorization to access a resource may be dynamically granted/yielded. We describe ongoing work on a model for specifying communication and dynamic authorization handling. We build upon the pi-calculus so as to enrich communication-based systems with authorization specification and delegation; here authorizations regard channel usage and delegation refers to the act of yielding an authorization to another party. Our model includes: (i a novel scoping construct for authorization, which allows to specify authorization boundaries, and (ii communication primitives for authorizations, which allow to pass around authorizations to act on a given channel. An authorization error may consist in, e.g., performing an action along a name which is not under an appropriate authorization scope. We introduce a typing discipline that ensures that processes never reduce to authorization errors, even when authorizations are dynamically delegated.

  12. 46 CFR 160.055-2 - Type and model.

    Science.gov (United States)

    2010-10-01

    ...) Standard, bib type, vinyl dip coated: (1) Model 62, adult (for persons weighing over 90 pounds); or (2) Model 66, child (for persons weighing less than 90 pounds); or (b) Standard, bib type, cloth covered;...

  13. A Realizability Model for Impredicative Hoare Type Theory

    DEFF Research Database (Denmark)

    Petersen, Rasmus Lerchedal; Birkedal, Lars; Nanevski, Alexandar

    2008-01-01

    We present a denotational model of impredicative Hoare Type Theory, a very expressive dependent type theory in which one can specify and reason about mutable abstract data types. The model ensures soundness of the extension of Hoare Type Theory with impredicative polymorphism; makes the connections...... to separation logic clear, and provides a basis for investigation of further sound extensions of the theory, in particular equations between computations and types....

  14. Isobar Model for Photoproduction of K+Sigma0 and K0Sigma+ on the Proton

    CERN Document Server

    Mart, T

    2005-01-01

    Kaon photoproductions on the proton gamma p --> K+Sigma0 and gamma p --> K0Sigma+ have been simultaneously analyzed by using isobar models and new SAPHIR data. The result shows that isobar models such as KAON MAID require more resonances in order to explain the data.

  15. Investigation of the formaldehyde differential absorption cross section at high and low spectral resolution in the simulation chamber SAPHIR

    Directory of Open Access Journals (Sweden)

    T. Brauers

    2007-07-01

    Full Text Available The results from a simulation chamber study on the formaldehyde (HCHO absorption cross section in the UV spectral region are presented. We performed 4 experiments at ambient HCHO concentrations with simultaneous measurements of two DOAS instruments in the atmosphere simulation chamber SAPHIR in Jülich. The two instruments differ in their spectral resolution, one working at 0.2 nm (broad-band, BB-DOAS, the other at 2.7 pm (high-resolution, HR-DOAS. Both instruments use dedicated multi reflection cells to achieve long light path lengths of 960 m and 2240 m, respectively, inside the chamber. During two experiments HCHO was injected into the clean chamber by thermolysis of well defined amounts of para-formaldehyde reaching mixing rations of 30 ppbV at maximum. The HCHO concentration calculated from the injection and the chamber volume agrees with the BB-DOAS measured value when the absorption cross section of Meller and Moortgat (2000 and the temperature coefficient of Cantrell (1990 were used for data evaluation. In two further experiments we produced HCHO in-situ from the ozone + ethene reaction which was intended to provide an independent way of HCHO calibration through the measurements of ozone and ethene. However, we found an unexpected deviation from the current understanding of the ozone + ethene reaction when CO was added to suppress possible oxidation of ethene by OH radicals. The reaction of the Criegee intermediate with CO could be 240 times slower than currently assumed. Based on the BB-DOAS measurements we could deduce a high-resolution cross section for HCHO which was not measured directly so far.

  16. Integrability of a New Type of Deformed XXZ Model

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    A new type of deformed XXZ model was constructed and diagonalized by the coordinate Bethe ansatz method. We obtained the energy and the Bethe ansatz equations of the model and also discussed some thermodynamics of the model.

  17. Investigation of spatial resolution and temporal performance of SAPHIRE (scintillator avalanche photoconductor with high resolution emitter readout) with integrated electrostatic focusing

    Science.gov (United States)

    Scaduto, David A.; Lubinsky, Anthony R.; Rowlands, John A.; Kenmotsu, Hidenori; Nishimoto, Norihito; Nishino, Takeshi; Tanioka, Kenkichi; Zhao, Wei

    2014-03-01

    We have previously proposed SAPHIRE (scintillator avalanche photoconductor with high resolution emitter readout), a novel detector concept with potentially superior spatial resolution and low-dose performance compared with existing flat-panel imagers. The detector comprises a scintillator that is optically coupled to an amorphous selenium photoconductor operated with avalanche gain, known as high-gain avalanche rushing photoconductor (HARP). High resolution electron beam readout is achieved using a field emitter array (FEA). This combination of avalanche gain, allowing for very low-dose imaging, and electron emitter readout, providing high spatial resolution, offers potentially superior image quality compared with existing flat-panel imagers, with specific applications to fluoroscopy and breast imaging. Through the present collaboration, a prototype HARP sensor with integrated electrostatic focusing and nano- Spindt FEA readout technology has been fabricated. The integrated electron-optic focusing approach is more suitable for fabricating large-area detectors. We investigate the dependence of spatial resolution on sensor structure and operating conditions, and compare the performance of electrostatic focusing with previous technologies. Our results show a clear dependence of spatial resolution on electrostatic focusing potential, with performance approaching that of the previous design with external mesh-electrode. Further, temporal performance (lag) of the detector is evaluated and the results show that the integrated electrostatic focusing design exhibits comparable or better performance compared with the mesh-electrode design. This study represents the first technical evaluation and characterization of the SAPHIRE concept with integrated electrostatic focusing.

  18. An indirect flat-panel detector with avalanche gain for low dose x-ray imaging: SAPHIRE (scintillator avalanche photoconductor with high resolution emitter readout)

    Science.gov (United States)

    Zhao, Wei; Li, Dan; Rowlands, J. A.; Egami, N.; Takiguchi, Y.; Nanba, M.; Honda, Y.; Ohkawa, Y.; Kubota, M.; Tanioka, K.; Suzuki, K.; Kawai, T.

    2008-03-01

    An indirect flat-imager with programmable avalanche gain and field emitter array (FEA) readout is being investigated for low-dose x-ray imaging with high resolution. It is made by optically coupling a structured x-ray scintillator CsI (Tl) to an amorphous selenium (a-Se) avalanche photoconductor called HARP (high-gain avalanche rushing photoconductor). The charge image created by HARP is read out by electron beams generated by the FEA. The proposed detector is called SAPHIRE (Scintillator Avalanche Photoconductor with HIgh Resolution Emitter readout). The avalanche gain of HARP depends on both a-Se thickness and applied electric field E Se. At E Se of > 80 V/μm, the avalanche gain can enhance the signal at low dose (e.g. fluoroscopy) and make the detector x-ray quantum noise limited down to a single x-ray photon. At high exposure (e.g. radiography), the avalanche gain can be turned off by decreasing E Se to < 70 V/μm. In this paper the imaging characteristics of the FEA readout method, including the spatial resolution and noise, were investigated experimentally using a prototype optical HARP-FEA image sensor. The potential x-ray imaging performance of SAPHIRE, especially the aspect of programmable gain to ensure wide dynamic range and x-ray quantum noise limited performance at the lowest exposure in fluoroscopy, was investigated.

  19. Model primary content type for multipurpose internet mail extensions

    Energy Technology Data Exchange (ETDEWEB)

    Nelson, S.; Parks, C.

    1997-01-01

    The purpose of this memo is to propose an update to Internet RFC 2045 to include a new primary content-type to be known as `model`. RFC 2045 [1] describes mechanisms for specifying and describing the format of Internet Message Bodies via content-type/subtype pairs. We believe that `model` defines a fundamental type of content with unique presentational, hardware, and processing aspects. Various subtypes of this primary type are immediately anticipated but will be covered under separate documents.

  20. Logic model needs for diverse facility types

    Energy Technology Data Exchange (ETDEWEB)

    Wilson, J.R.

    1995-10-01

    This paper compares the characteristics of fault trees (where initiators are developed within the fault tree) vs. event trees (where the nodes are developed by fault trees). This comparison requires some additional discussion on the subtlety of initiators. Difficulties when analyzing various reactor-type and processing facilities are discussed to illustrate the particular characteristics of each type of logic. The intent is to allow probabilistic risk assessment (PRA) analysts to be {open_quotes}bi-logical,{close_quotes} or equally comfortable with event-tree or fault-tree logic, knowing when to apply each.

  1. Studies of mixed HEU-LEU-MTR cores using 3D models

    Energy Technology Data Exchange (ETDEWEB)

    Haenggi, P.; Lehmann, E.; Hammer, J.; Christen, R. [Paul Scherrer Institute, Villigen (Switzerland)

    1997-08-01

    Several different core loadings were assembled at the SAPHIR research reactor in Switzerland combining the available types of MTR-type fuel elements, consisting mainly of both HEU and LEU fuel. Bearing in mind the well known problems which can occur in such configurations (especially power peaking), investigations have been carried out for each new loading with a 2D neutron transport code (BOXER). The axial effects were approximated by a global buckling value and therefore the radial effects could be studied in considerably detail. Some of the results were reported at earlier RERTR meetings and were compared to those obtained by other methods and with experimental values. For the explicit study of the third dimension of the core, another code (SILWER), which has been developed in PSI for LWR power plant cores, has been selected. With the help of an adapted model for the MTR-core of SAPHIR, several important questions have been addressed. Among other aspects, the estimation of the axial contribution to the hot channel factors, the influence of the control rod position and of the Xe-poisoning on the power distribution were studied. Special attention was given to a core position where a new element was assumed placed near a empty, water filled position. The comparison of elements of low and high enrichments at this position was made in terms of the induced power peaks, with explicit consideration of axial effects. The program SILWER has proven to be applicable to MTR-cores for the investigation of axial effects. For routine use as for the support of reactor operation, this 3D code is a good supplement to the standard 2D model.

  2. A Model of PCF in Guarded Type Theory

    DEFF Research Database (Denmark)

    Paviotti, Marco; Møgelberg, Rasmus Ejlers; Birkedal, Lars

    2015-01-01

    of coinductive types. In this paper we investigate how type theory with guarded recursion can be used as a metalanguage for denotational semantics useful both for constructing models and for proving properties of these. We do this by constructing a fairly intensional model of PCF and proving it computationally...... adequate. The model construction is related to Escardo's metric model for PCF, but here everything is carried out entirely in type theory with guarded recursion, including the formulation of the operational semantics, the model construction and the proof of adequacy....

  3. 2 types of spicules "observed" in 3D realistic models

    CERN Document Server

    Martínez-Sykora, Juan

    2010-01-01

    Realistic numerical 3D models of the outer solar atmosphere show two different kind of spicule-like phenomena, as also observed on the solar limb. The numerical models are calculated using the 2 types of spicules "observed" in 3D realistic models Oslo Staggered Code (OSC) to solve the full MHD equations with non-grey and NLTE radiative transfer and thermal conduction along the magnetic field lines. The two types of spicules arise as a natural result of the dynamical evolution in the models. We discuss the different properties of these two types of spicules, their differences from observed spicules and what needs to be improved in the models.

  4. Quantitative and qualitative assessment of diurnal variability in tropospheric humidity using SAPHIR on-board Megha-Tropiques

    Science.gov (United States)

    Uma, K. N.; Das, Siddarth Shankar

    2016-08-01

    The global diurnal variability of relative humidity (RH) from August 2012 to May 2014 is discussed for the first time using 'Sounder for Atmospheric Profiling of Humidity in the Inter-tropical Regions (SAPHIR)', a microwave humidity sounder onboard Megha-Tropiques (MT). It is superior to other microwave satellite humidity sounders in terms of its higher repetitive cycle in the tropics owing to its low-inclination orbit and the availability of six dedicated humidity sounding channels. The six layers obtained are 1000-850, 850-700, 700-550, 550-400, 400-250 and 250-100 hPa. Three hourly data over a month has been combined using equivalent day analysis to attain a composite profile of complete diurnal cycle in each grid (2.5°×2.5°). A distinct diurnal variation is obtained over the continental and the oceanic regions at all the layers. The magnitude in the lower tropospheric humidity (LTH), middle tropospheric humidity (MTH) and the upper tropospheric humidity (UTH) show a large variability over the continental regions compared to that over oceans. The monthly variability of the diurnal variation over the years has also been discussed by segregating into five different continental and four different oceanic regions. Afternoon peaks dominate in the LTH over the land and the desert regions. The MTH is found to vary between the evening and the early morning hours over different geographical regions and not as consistent as that of the LTH. The UTH maximum magnitude is generally observed during the early morning hours, over the continents. Interestingly, the Oceanic regions are found to have a dominant magnitude in the afternoon hours similar to that of the continents in the LTH, evening maximum in the MTH and the early morning maximum in the UTH. The underlying mechanisms involved in the variability of humidity over different regions are also discussed. The study reveals the complexity involved in the understanding the diurnal variability over the continents and open

  5. Modeling Type-IIn Interacting Supernovae

    Science.gov (United States)

    McDowell, Austin; Duffell, Paul; Kasen, Daniel

    2017-01-01

    Spectra of Type-IIn Supernovae (SNe) have shown evidence of interaction between SN ejecta and a surrounding circumstellar medium (CSM). Namely, narrow Hydrogen lines indicate that the fast moving ejecta slows after it collides with the slow moving CSM. However, observations of eta-Carinae and spectropolarimetry of SN2009ip during its 2012 explosion have shown that the CSM may often be asymmetric. In this study, we investigate the ability of an asymmetric CSM to disguise the characteristic narrow H lines expected from Type-IIn SNe. We perform two-dimensional hydrodynamic simulations of the interaction between supernova ejecta and CSM. The simulations are run using the moving-mesh hydrodynamics code JET. Previous studies have ignored possible asymmetries by limiting their calculations to one-dimension or assuming a spherically symmetric CSM. We calculate shock propagation within the disk and CSM heating rate to produce mock-bolometric light curves. We also track unshocked CSM mass and speculate on its effects on the observation of H lines.

  6. Statefinder Diagnostic for Born-Infeld Type Dark Energy Model

    Institute of Scientific and Technical Information of China (English)

    HUANG Zeng-Guang; LU Hui-Qing

    2008-01-01

    Using a new method called the statefinder diagnostics which can make one dark energy model differ from the others, we investigate the dynamics of Born-Infeld (B-I) type dark energy model. The evolution trajectory of B-I type dark energy with Mexican hat potential model with respect to e-folding time N is shown in the r (s) diagram, When the parameter of noncanonical kinetic energy term η→0 or kinetic energy ψ2→0, the B-I type dark energy (K-essence) model reduces to the quintessence model or the ACDM model corresponding to the statefinder pair {r, s}={1, 0} respectively. As a result, the evolution trajectory of our model in the r (s) diagram in Mexican hat potential is quite different from those of other dark energy models. The current values of parameters Ω,ψ and ω,ψ in this model meet the latest observations WMAP5 well.

  7. Loop quantum cosmology of Bianchi type IX models

    CERN Document Server

    Wilson-Ewing, Edward

    2010-01-01

    The loop quantum cosmology "improved dynamics" of the Bianchi type IX model are studied. The action of the Hamiltonian constraint operator is obtained via techniques developed for the Bianchi type I and type II models, no new input is required. It is shown that the big bang and big crunch singularities are resolved by quantum gravity effects. We also present the effective equations which provide modifications to the classical equations of motion due to quantum geometry effects.

  8. Loop quantum cosmology of Bianchi type IX models

    Science.gov (United States)

    Wilson-Ewing, Edward

    2010-08-01

    The loop quantum cosmology “improved dynamics” of the Bianchi type IX model are studied. The action of the Hamiltonian constraint operator is obtained via techniques developed for the Bianchi type I and type II models, no new input is required. It is shown that the big bang and big crunch singularities are resolved by quantum gravity effects. We also present effective equations which provide quantum geometry corrections to the classical equations of motion.

  9. Type-I integrable quantum impurities in the Heisenberg model

    CERN Document Server

    Doikou, Anastasia

    2013-01-01

    Type-I quantum impurities are investigated in the context of the integrable Heisenberg model. This type of defects is associated to the (q)-harmonic oscillator algebra. The transmission matrices associated to this particular type of defects are computed via the Bethe ansatz methodology for the XXX model, as well as for the critical and non-critical XXZ spin chain. In the attractive regime of the critical XXZ spin chain the transmission amplitudes for the breathers are also identified.

  10. Type-I integrable quantum impurities in the Heisenberg model

    Energy Technology Data Exchange (ETDEWEB)

    Doikou, Anastasia, E-mail: adoikou@upatras.gr

    2013-12-21

    Type-I quantum impurities are investigated in the context of the integrable Heisenberg model. This type of defects is associated to the (q)-harmonic oscillator algebra. The transmission matrices associated to this particular type of defects are computed via the Bethe ansatz methodology for the XXX model, as well as for the critical and non-critical XXZ spin chain. In the attractive regime of the critical XXZ spin chain the transmission amplitudes for the breathers are also identified.

  11. Type-2 fuzzy logic uncertain systems’ modeling and control

    CERN Document Server

    Antão, Rómulo

    2017-01-01

    This book focuses on a particular domain of Type-2 Fuzzy Logic, related to process modeling and control applications. It deepens readers’understanding of Type-2 Fuzzy Logic with regard to the following three topics: using simpler methods to train a Type-2 Takagi-Sugeno Fuzzy Model; using the principles of Type-2 Fuzzy Logic to reduce the influence of modeling uncertainties on a locally linear n-step ahead predictor; and developing model-based control algorithms according to the Generalized Predictive Control principles using Type-2 Fuzzy Sets. Throughout the book, theory is always complemented with practical applications and readers are invited to take their learning process one step farther and implement their own applications using the algorithms’ source codes (provided). As such, the book offers avaluable referenceguide for allengineers and researchers in the field ofcomputer science who are interested in intelligent systems, rule-based systems and modeling uncertainty.

  12. Measurement of the reaction {gamma}p{yields}K{sup 0}{sigma}{sup +} for photon energies up to 2.65 GeV with the SAPHIR detector at ELSA; Messung der Reaktion {gamma}p {yields} K{sup 0}{sigma}{sup +} fuer Photonenergien bis 2.65 GeV mit dem SAPHIR-Detektor an ELSA

    Energy Technology Data Exchange (ETDEWEB)

    Lawall, R.

    2004-01-01

    The reaction {gamma}p {yields} K{sup 0}{sigma}{sup +} was measured with the SAPHIR-detector at ELSA during the run periods 1997 and 1998. Results were obtained for cross sections in the photon energy range from threshold up to 2.65 GeV for all production angles and for the {sigma}{sup +}-polarization. Emphasis has been put on the determination and reduction of the contributions of background reactions and the comparison with other measurements and theoretical predictions. (orig.)

  13. Implementation of IEC Generic Model Type 1A using RTDS

    DEFF Research Database (Denmark)

    Cha, Seung-Tae; Wu, Qiuwei; Zhao, Haoran

    2012-01-01

    This paper presents the implementation of the IEC generic model of Type 1 wind turbine generator (WTG) in the real time digital simulator (RTDS) environment. The model is based on the IEC 61400 TC88 under wind turbine working group’s standardization efforts are implemented. Several case studies...... have been carried out to verify the dynamic performance of the IEC generic Type 1 WTG model under both steady state and dynamic conditions. The case study results show that the IEC generic Type 1 WTG model can represent the relevant dynamic behaviour of wind power generation to ensure grid integration...

  14. Towards an Existential Types Model for Java with Wildcards

    DEFF Research Database (Denmark)

    Cameron, Nicholas; Drossopoulou, Sophia; Ernst, Erik

    2007-01-01

    Wildcards extend Java generics by softening the mismatch between subtype and parametric polymorphism. Although they are a key part of the Java 5.0 programming language, a type system including wildcards has never been proven type sound. Wildcards have previously been formalised as existential types....... In this paper we extend FGJ, a featherweight formalisation of Java with generics, with existential types. We prove that this calculus, ExistsJ, is type sound, and illustrate how it models wildcards in the Java Programming Language. ExistsJ is not a full model for Java wildcards, because it does not support...... lower bounds for wildcards. We discuss why ExistsJ can not be easily extended with lower bounds, and how full Java wildcards could be modelled in a type sound way....

  15. A new vector Preisach-type model of hysteresis

    Energy Technology Data Exchange (ETDEWEB)

    Adly, A.A.; Mayergoyz, I.D. (EE Department and Institute for Advanced Computer Studies, University of Maryland, College Park, Maryland 20742 (United States))

    1993-05-15

    New isotropic vector Preisach-type models of hysteresis are introduced. These new models contain additional unknown functions. This presents the opportunity to incorporate more experimental data in the identification process than in the case of previously suggested vector Preisach models, thus leading to more accurate models. The solution of the identification problem is discussed and some results of experimental testing of these models are reported.

  16. The Collins Model and the Eutectic-Type and the Peritectic-Type Phase Diagrams

    Institute of Scientific and Technical Information of China (English)

    XIE Chuan-Mei; CHEN Li-Rong

    2003-01-01

    From the Gibbs free energy and the equations of two-phase equilibrium curves of the two-dimensionalbinary system which has the Lennard-Jones potential, using the Collins model, the eutectic-type phase diagram and theperitectic-type phase diagram of the binary system are obtained, whose results are quite similar to the behavior of thethree-dimensional (3D) substances.

  17. Comparison of Relative Humidity obtained from SAPHIR on board Megha-Tropiques and Ground based Microwave Radiometer Profiler over an equatorial station

    Science.gov (United States)

    Renju, Ramachandran Pillai; Uma, K. N.; Krishna Moorthy, K.; Mathew, Nizy; Raju C, Suresh

    A comparison has been made between the SAPHIR on board Megha-Tropiques (MT) derived Relative Humidity (RH (%)) with that derived from a ground based multi-frequency Microwave Radiometer Profiler (MRP) observations over an equatorial station Thiruvananthapuram (8.5(°) N and 76.9(°) E) for a one year period. As a first step, the validation of MRP has been made against the radiosonde for two years (2010 and 2011) during the Indian monsoon period July-September. This analysis shows a wet bias below 6 km and dry bias above. The comparison between the MRP and the MT derived RH has been made at five different altitudinal levels (0.75, 2.25, 4.0, 6.25 and 9.2 km range) strictly under clear sky condition. The regression analysis between the two reveals very good correlation (>0.8) in the altitudinal layer of 2.25 to 6.25 km. The differences between the two observations had also been explained interms of percentage of occurrence between MT and the MRP at each altitudinal layer. About 70-80% of the time, the difference in the RH is found to below 10% at first three layer. The RMSE of 2% is observed at almost all the height layers. The differences have been attributed to the different measurement and retrieval techniques involved in the ground based and satellite based measurements. Since MRP frequecy channels are not sensitive to small water vapor variabilities above 6 km, large differences are observed. Radiative Transfer computation for the channels of both MRP and SAPHIR will be carried out to understand the variabilities.

  18. A note on tilted Bianchi type VIh models: the type III bifurcation

    Science.gov (United States)

    Coley, A. A.; Hervik, S.

    2008-10-01

    In this note we complete the analysis of Hervik, van den Hoogen, Lim and Coley (2007 Class. Quantum Grav. 24 3859) of the late-time behaviour of tilted perfect fluid Bianchi type III models. We consider models with dust, and perfect fluids stiffer than dust, and eludicate the late-time behaviour by studying the centre manifold which dominates the behaviour of the model at late times. In the dust case, this centre manifold is three-dimensional and can be considered a double bifurcation as the two parameters (h and γ) of the type VIh model are varied. We therefore complete the analysis of the late-time behaviour of tilted ever-expanding Bianchi models of types I VIII.

  19. On a Boltzmann-type price formation model

    KAUST Repository

    Burger, Martin

    2013-06-26

    In this paper, we present a Boltzmann-type price formation model, which is motivated by a parabolic free boundary model for the evolution of price presented by Lasry and Lions in 2007. We discuss the mathematical analysis of the Boltzmann-type model and show that its solutions converge to solutions of the model by Lasry and Lions as the transaction rate tends to infinity. Furthermore, we analyse the behaviour of the initial layer on the fast time scale and illustrate the price dynamics with various numerical experiments. © 2013 The Author(s) Published by the Royal Society. All rights reserved.

  20. Special Geometries Emerging from Yang-Mills Type Matrix Models

    CERN Document Server

    Blaschke, Daniel N

    2011-01-01

    I review some recent results which demonstrate how various geometries, such as Schwarzschild and Reissner-Nordstroem, can emerge from Yang-Mills type matrix models with branes. Furthermore, explicit embeddings of these branes as well as appropriate Poisson structures and star-products which determine the non-commutativity of space-time are provided. These structures are motivated by higher order terms in the effective matrix model action which semi-classically lead to an Einstein-Hilbert type action.

  1. Vectorial Preisach-type model designed for parallel computing

    Energy Technology Data Exchange (ETDEWEB)

    Stancu, Alexandru [Department of Solid State and Theoretical Physics, Al. I. Cuza University, Blvd. Carol I, 11, 700506 Iasi (Romania)]. E-mail: alstancu@uaic.ro; Stoleriu, Laurentiu [Department of Solid State and Theoretical Physics, Al. I. Cuza University, Blvd. Carol I, 11, 700506 Iasi (Romania); Andrei, Petru [Electrical and Computer Engineering, Florida State University, Tallahassee, FL (United States); Electrical and Computer Engineering, Florida A and M University, Tallahassee, FL (United States)

    2007-09-15

    Most of the hysteresis phenomenological models are scalar, while all the magnetization processes are vectorial. The vector models-phenomenological or micromagnetic (physical)-are time consuming and sometimes difficult to implement. In this paper, we introduce a new vector Preisach-type model that uses micromagnetic results to simulate the magnetic response of a system of several tens of thousands of pseudo-particles. The model has a modular structure that allows easy implementation for parallel computing.

  2. A model of PCF in guarded type theory

    DEFF Research Database (Denmark)

    Paviotti, Marco; Møgelberg, Rasmus Ejlers; Birkedal, Lars

    2015-01-01

    Guarded recursion is a form of recursion where recursive calls are guarded by delay modalities. Previous work has shown how guarded recursion is useful for constructing logics for reasoning about programming languages with advanced features, as well as for constructing and reasoning about elements...... of coinductive types. In this paper we investigate how type theory with guarded recursion can be used as a metalanguage for denotational semantics useful both for constructing models and for proving properties of these. We do this by constructing a fairly intensional model of PCF and proving it computationally...... adequate. The model construction is related to Escardo's metric model for PCF, but here everything is carried out entirely in type theory with guarded recursion, including the formulation of the operational semantics, the model construction and the proof of adequacy...

  3. Two types of glitches in a solid quark star model

    CERN Document Server

    Lu, Jiguang

    2015-01-01

    The glitch of anomalous X-ray pulsars \\& soft gamma repeaters (AXP/SGRs) usually accompanied with detectable energy releases manifesting as X-ray bursts or outbursts, while the glitch of some pulsars like Vela release negligible energy. We find that these two types of glitch can naturally correspond to two types of starquake of solid stars. So far only quark star and quark cluster star model develop a solid star model. Then the two types of glitch may be an implication that the pulsar is composed by quark matter or quark cluster matter.

  4. Bianchi type IX string cosmological model in general relativity

    Indian Academy of Sciences (India)

    Raj Bali; Shuchi Dave

    2001-04-01

    We have investigated Bianchi type IX string cosmological models in general relativity. To get a determinate solution, we have assumed a condition ρ= i.e. rest energy density for a cloud of strings is equal to the string tension density. The various physical and geometrical aspects of the models are also discussed.

  5. HYDRODYNAMICAL MODELS OF TYPE II-P SUPERNOVA LIGHT CURVES

    Directory of Open Access Journals (Sweden)

    M. C. Bersten

    2009-01-01

    Full Text Available We present progress in light curve models of type II-P supernovae (SNe II-P obtained using a newly devel- oped, one-dimensional hydrodynamic code. Using simple initial models (polytropes, we reproduced the global behavior of the observed light curves and we analyzed the sensitivity of the light curves to the variation of free parameters.

  6. STRONG NORMALIZATION IN TYPE SYSTEMS - A MODEL THEORETICAL APPROACH

    NARCIS (Netherlands)

    TERLOUW, J

    1995-01-01

    Tait's proof of strong normalization for the simply typed lambda-calculus is interpreted in a general model theoretical framework by means of the specification of a certain theory T and a certain model U of T. The argumentation is partly reduced to formal predicate logic by the application of

  7. Modelling spatial vagueness based on type-2 fuzzy set

    Institute of Scientific and Technical Information of China (English)

    DU Guo-ning; ZHU Zhong-ying

    2006-01-01

    The modelling and formal characterization of spatial vagueness plays an increasingly important role in the implementation of Geographic Information System (GIS). The concepts involved in spatial objects of GIS have been investigated and acknowledged as being vague and ambiguous. Models and methods which describe and handle fuzzy or vague (rather than crisp or determinate) spatial objects, will be more necessary in GIS. This paper proposes a new method for modelling spatial vagueness based on type-2 fuzzy set, which is distinguished from the traditional type-1 fuzzy methods and more suitable for describing and implementing the vague concepts and objects in GIS.

  8. The Application of Phase Type Distributions for Modelling Queuing Systems

    Directory of Open Access Journals (Sweden)

    EIMUTIS VALAKEVICIUS

    2007-12-01

    Full Text Available Queuing models are important tools for studying the performance of complex systems, but despite the substantial queuing theory literature, it is often necessary to use approximations in the case the system is nonmarkovian. Phase type distribution is by now indispensable tool in creation of queuing system models. The purpose of this paper is to suggest a method and software for evaluating queuing approximations. A numerical queuing model with priorities is used to explore the behaviour of exponential phase-type approximation of service-time distribution. The performance of queuing systems described in the event language is used for generating the set of states and transition matrix between them. Two examples of numerical models are presented – a queuing system model with priorities and a queuing system model with quality control.

  9. A random effects epidemic-type aftershock sequence model.

    Science.gov (United States)

    Lin, Feng-Chang

    2011-04-01

    We consider an extension of the temporal epidemic-type aftershock sequence (ETAS) model with random effects as a special case of a well-known doubly stochastic self-exciting point process. The new model arises from a deterministic function that is randomly scaled by a nonnegative random variable, which is unobservable but assumed to follow either positive stable or one-parameter gamma distribution with unit mean. Both random effects models are of interest although the one-parameter gamma random effects model is more popular when modeling associated survival times. Our estimation is based on the maximum likelihood approach with marginalized intensity. The methods are shown to perform well in simulation experiments. When applied to an earthquake sequence on the east coast of Taiwan, the extended model with positive stable random effects provides a better model fit, compared to the original ETAS model and the extended model with one-parameter gamma random effects.

  10. Spectra of Anderson Type Models with Decaying Randomness

    Indian Academy of Sciences (India)

    M Krishna; K B Sinha

    2001-05-01

    In this paper we consider some Anderson type models, with free parts having long range tails with the random perturbations decaying at different rates in different directions and prove that there is a.c. spectrum in the model which is pure. In addition, we show that there is pure point spectrum outside some interval. Our models include potentials decaying in all directions in which case absence of singular continuous spectrum is also shown.

  11. Bianchi Type V magnetized string dust cosmological models with Petrov-type degenerate

    Indian Academy of Sciences (India)

    Raj Bali; Umesh K Pareek

    2009-05-01

    Bianchi Type V massive string cosmological models with free gravitational field of Petrov Type degenerate in the presence of magnetic field with variable magnetic permeability are investigated. The magnetic field is due to an electric current produced along the -axis. The 23 is the only non-vanishing component of electromagnetic field tensor . Maxwell's equations [;] = 0 and $F_{ij}^{ij} = 0$ are satisfied by 23 = constant. The behaviour of the model in the presence and absence of magnetic field and other physical aspects are also discussed.

  12. Improvement of TNO type trailing edge noise models

    DEFF Research Database (Denmark)

    Fischer, Andreas; Bertagnolio, Franck; Aagaard Madsen, Helge

    2016-01-01

    The paper describes an improvement of the so-called TNO model to predict the noise emission from aerofoil sections due to the interaction of the boundary layer turbulence with the trailing edge. The surface pressure field close to the trailing edge acts as source of sound in the TNO model....... It is computed by solving a Poisson equation which includes flow turbulence cross correlation terms. Previously published TNO type models used the assumption of Blake to simplify the Poisson equation. This paper shows that the simplification should not be used. We present a new model which fully models...... the turbulence cross correlation terms. The predictions of the new model are in better agreement with measurements of the surface pressure and far field sound spectra. The computational cost of the new model is only slightly higher than the one of the TNO model, because we derived an analytical solution...

  13. A Maintenance Model Based on Phase Type Distribution for Equipment under Two Types of Failures

    Institute of Scientific and Technical Information of China (English)

    YIN Xiao-hu; WEN Xi-sen; YANG Yong-min; QIAN Yan-ling

    2007-01-01

    A maintenance model is put forward for equipment, which is subjected to internal and external failures. In the model, two maintenance policies-perfect minimal repair and replacement are considered. The operational time has a phase type distribution (PH distribution). Failures' arrival follows a Markovian Arrival Process (MAP). Some failures require the replacement of the system, and others minimal repairs. The performance measures-the mean number of minimal repairs and replacements are analyzed and calculated.

  14. Bianchi Type Ⅲ String Cosmological Model with Bulk Viscosity

    Institute of Scientific and Technical Information of China (English)

    WANGXing-Xiang

    2004-01-01

    The Bianchi type Ⅲ cosmological model for a cloud string with bulk viscosity are presented. To obtain a determinate model, an equation of state ρ=kλ and a relation between metric potentials B = Cn are assumed. The physical and geometric aspects of the model are also discussed. The model describes a shearing non-rotating continuously expanding universe with a big-bang start, and the relation between the coefficient of bulk viscosity and the energy density is ζ∝ρ1/2.

  15. Bianchi Type Ⅲ String Cosmological Model with Bulk Viscosity

    Institute of Scientific and Technical Information of China (English)

    WANG Xing-Xiang

    2004-01-01

    The Bianchi type Ⅲ cosmological model for a cloud string with bulk viscosity are presented. To obtaina determinate model, an equation of state p = κλ and a relation between metric potentials B = Cn are assumed. Thephysical and geometric aspects of the model are also discussed. The model describes a shearing non-rotating continuouslyexpanding universe with a big-bang start, and the relation between the coefficient of bulk viscosity and the energy densityis ζ∝1 p1/2.

  16. Modeling And Position Control Of Scara Type 3D Printer

    Directory of Open Access Journals (Sweden)

    Ahmet Saygamp305n Ogulmuamp351

    2015-08-01

    Full Text Available In this work a scara robot type 3D printer system is dynamically modeled and position control of the system is realized. For this aim computer aided design model of three degrees of freedom robotic system is created using SolidWorks program then obtained model is exported to MATLABSimMechanics software for position control. Also mathematical model of servo motors used in robotic 3D printer system is included in control methodology to design proportional controllers. Uncontrolled and controlled position results are simulated and given in the form of the graphics.

  17. Polarisation Spectral Synthesis For Type Ia Supernova Explosion Models

    Science.gov (United States)

    Bulla, Mattia

    2017-02-01

    Despite their relevance across a broad range of astrophysical research topics, Type Ia supernova explosions are still poorly understood and answers to the questions of when, why and how these events are triggered remain unclear. In this respect, polarisation offers a unique opportunity to discriminate between the variety of possible scenarios. The observational evidence that Type Ia supernovae are associated with rather low polarisation signals (smaller than a few per cent) places strong constraints for models and calls for modest asphericities in the progenitor system and/or explosion mechanism.The goal of this thesis is to assess the validity of contemporary Type Ia supernova explosion models by testing whether their predicted polarisation signatures can account for the small signals usually observed. To this end, we have implemented and tested an innovative Monte Carlo scheme in the radiative transfer code artis. Compared to previous Monte Carlo approaches, this technique produces synthetic observables (light curves, flux and polarisation spectra) with a substantial reduction in the Monte Carlo noise and therefore in the required computing time. This improvement is particularly crucial for our study as we aim to extract very weak polarisation signals, comparable to those detected in Type Ia supernovae. We have also demonstrated the applicability of this method to other classes of supernovae via a preliminary study of the first spectropolarimetry observations of superluminous supernovae.Using this scheme, we have calculated synthetic spectropolarimetry for three multi-dimensional explosion models recently proposed as promising candidates to explain Type Ia supernovae. Our findings highlight the power of spectropolarimetry in testing and discriminating between different scenarios. While all the three models predict light curves and flux spectra that are similar to each others and reproduce those observed in Type Ia supernovae comparably well, polarisation does

  18. From Enneagram to Nine Types Temperament Model: A Proposal

    OpenAIRE

    Yılmaz, Enver Demirel; Gençer, Ali Görkem; Ünal, Özge; Aydemir, Ömer

    2014-01-01

    Temperament, character and personality concepts are addressed by many disciplines that study interpersonal differences. Although each of these concepts is related with each other, they are different and often used instead of one another. Nine Types Temperament Model (NTTM), a new temperament model formulated with the interpretation of Enneagram System, explains the definition, limit, scope and interrelations of these concepts, as well as presents a new perspective on studying the differences ...

  19. Bianchi type-V string cosmological models in general relativity

    Indian Academy of Sciences (India)

    Anil Kumar Yadav; Vineet Kumar Yadav; Lallan Yadav

    2011-04-01

    Bianchi type-V string cosmological models in general relativity are investigated. To get the exact solution of Einstein’s field equations, we have taken some scale transformations used by Camci et al [Astrophys. Space Sci. 275, 391 (2001)]. It is shown that Einstein’s field equations are solvable for any arbitrary cosmic scale function. Solutions for particular forms of cosmic scale functions are also obtained. Some physical and geometrical aspects of the models are discussed.

  20. Uniqueness of Petrov type D spatially inhomogeneous irrotational silent models

    CERN Document Server

    Apostolopoulos, P S; Apostolopoulos, Pantelis S; Carot, Jaume

    2006-01-01

    The consistency of the constraint with the evolution equations for spatially inhomogeneous and irrotational silent (SIIS) models of Petrov type I, demands that the former are preserved along the timelike congruence represented by the velocity of the dust fluid, leading to an infinite set of non-trivial constraints. This fact has been used to conjecture that the resulting models correspond to the spatially homogeneous (SH) models of Bianchi type I, at least for the case where the cosmological constant vanish. By exploiting the full set of the constraint equations as expressed in the 1+3 covariant formalism and using elements from the theory of the spacelike congruences, we provide a direct and simple proof of this conjecture for vacuum and dust fluid models, which shows that the Szekeres family of solutions represents the most general class of SIIS models. The suggested procedure also shows that, the uniqueness of the spatially inhomogeneous and irrotational models of Petrov type D is not affected by the prese...

  1. Inhomogeneous generalizations of Bianchi type VIh models with perfect fluid

    Science.gov (United States)

    Roy, S. R.; Prasad, A.

    1991-07-01

    Inhomogeneous universes admitting an Abelian G2 of isometry and filled with perfect fluid have been derived. These contain as special cases exact homogeneous universes of Bianchi type VIh. Many of these universes asymptotically tend to homogeneous Bianchi VIh universes. The models have been discussed for their physical and kinematical behaviors.

  2. Continuous media interpretation of supersymmetric Wess-Zumino type models

    Energy Technology Data Exchange (ETDEWEB)

    Letelier, P.S. [Universidade Estadual de Campinas (Brazil). Departamento de Matematica Aplicada; Zanchin, V.T. [Departamento de Fisica-CCNE, Universidade Federal de Santa Maria, 97119, Santa Maria, R.S. (Brazil)

    1995-02-20

    Supersymmetric Wess-Zumino type models are considered as classical material media that can be interpreted as fluids of ordered strings with heat flow along the strings, or a mixture of fluids of ordered strings with either a cloud of particles or a flux of directed radiation. ((orig.))

  3. Magnetostriction simulation using anisotropic vector Preisach-type models

    Energy Technology Data Exchange (ETDEWEB)

    Adly, A.A. [Cairo Univ., Giza (Egypt). Electric Power and Machines Dept.; Mayergoyz, I.D. [Univ. of Maryland, College Park, MD (United States). Electrical Engineering Dept.

    1996-09-01

    Magnetic materials exhibiting gigantic magnetostriction, especially Terfenol, are currently being widely used in fine positioning and active vibration damping devices. By involving accurate magnetostriction models during design stages, precision of such devices may be significantly enhanced. In this paper a straight-forward approach that employs anisotropic vector Preisach-type hysteresis models in simulating field-stress effects on magnetic materials is presented. Formulation of the proposed model is given and its identification problem is solved. The presented approach has been numerically implemented and numerous digital computer simulations have been performed for Terfenol material. Sample simulation results as well as comparisons with experimentally observed magnetostriction curves are reported in the paper.

  4. Type-2 fuzzy graphical models for pattern recognition

    CERN Document Server

    Zeng, Jia

    2015-01-01

    This book discusses how to combine type-2 fuzzy sets and graphical models to solve a range of real-world pattern recognition problems such as speech recognition, handwritten Chinese character recognition, topic modeling as well as human action recognition. It covers these recent developments while also providing a comprehensive introduction to the fields of type-2 fuzzy sets and graphical models. Though primarily intended for graduate students, researchers and practitioners in fuzzy logic and pattern recognition, the book can also serve as a valuable reference work for researchers without any previous knowledge of these fields. Dr. Jia Zeng is a Professor at the School of Computer Science and Technology, Soochow University, China. Dr. Zhi-Qiang Liu is a Professor at the School of Creative Media, City University of Hong Kong, China.

  5. Dosha brain-types: A neural model of individual differences

    Directory of Open Access Journals (Sweden)

    Frederick T Travis

    2015-01-01

    Full Text Available This paper explores brain patterns associated with the three categories of regulatory principles of the body, mind, and behavior in Ayurveda, called Vata, Pitta, and Kapha dosha. A growing body of research has reported patterns of blood chemistry, genetic expression, physiological states, and chronic diseases associated with each dosha type. Since metabolic and growth factors are controlled by the nervous system, each dosha type should be associated with patterns of functioning of six major areas of the nervous system: The prefrontal cortex, the reticular activating system, the autonomic nervous system, the enteric nervous system, the limbic system, and the hypothalamus. For instance, the prefrontal cortex, which includes the anterior cingulate, ventral medial, and the dorsal lateral cortices, would exhibit a high range of functioning in the Vata brain-type leading to the possibility of being easily overstimulated. The Vata brain-type performs activity quickly. Learns quickly and forgets quickly. Their fast mind gives them an edge in creative problem solving. The Pitta brain-type reacts strongly to all challenges leading to purposeful and resolute actions. They never give up and are very dynamic and goal oriented. The Kapha brain-type is slow and steady leading to methodical thinking and action. They prefer routine and needs stimulation to get going. A model of dosha brain-types could provide a physiological foundation to understand individual differences. This model could help individualize treatment modalities to address different mental and physical dysfunctions. It also could explain differences in behavior seen in clinical as well as in normal populations.

  6. Fitting the Two-Higgs-Doublet model of type II

    CERN Document Server

    Eberhardt, Otto

    2014-01-01

    We present the current status of the Two-Higgs-Doublet model of type II. Taking into account all available relevant information, we exclude at $95$% CL sizeable deviations of the so-called alignment limit, in which all couplings of the light CP-even Higgs boson $h$ are Standard-Model-like. While we can set a lower limit of $240$ GeV on the mass of the pseudoscalar Higgs boson at $95$% CL, the mass of the heavy CP-even Higgs boson $H$ can be even lighter than $200$ GeV. The strong constraints on the model parameters also set limits on the triple Higgs couplings: the $hhh$ coupling in the Two-Higgs-Doublet model of type II cannot be larger than in the Standard Model, while the $hhH$ coupling can maximally be $2.5$ times the size of the Standard Model $hhh$ coupling, assuming an $H$ mass below $1$ TeV. The selection of benchmark scenarios which maximize specific effects within the allowed regions for further collider studies is illustrated for the $H$ branching fraction to fermions and gauge bosons. As an exampl...

  7. Eye Typing using Markov and Active Appearance Models

    DEFF Research Database (Denmark)

    Hansen, Dan Witzner; Hansen, John Paulin; Nielsen, Mads

    2002-01-01

    multi-modal interactions based on video tracking systems. Robust methods are needed to track the eyes using web cameras due to the poor image quality. A real-time tracking scheme using a mean-shift color tracker and an Active Appearance Model of the eye is proposed. It is possible from this model......We propose a non-intrusive eye tracking system intended for the use of everyday gaze typing using web cameras. We argue that high precision in gaze tracking is not needed for on-screen typing due to natural language redundancy. This facilitates the use of low-cost video components for advanced...... to infer the state of the eye such as eye corners and the pupil location under scale and rotational changes....

  8. Modelling of W UMa-type variable stars

    Directory of Open Access Journals (Sweden)

    P. L. Skelton

    2010-01-01

    Full Text Available W Ursae Majoris (W UMa-type variable stars are over-contact eclipsing binary stars. To understand how these systems form and evolve requires observations spanning many years, followed by detailed models of as many of them as possible. The All Sky Automated Survey (ASAS has an extensive database of these stars. Using the ASAS V band photometric data, models of W UMatype stars are being created to determine the parameters of these stars. This paper discusses the classification of eclipsing binary stars, the methods used to model them as well as the results of the modelling of ASAS 120036–3915.6, an over-contact eclipsing binary star that appears to be changing its period.

  9. MAXIMUM LIKELIHOOD ESTIMATION IN GENERALIZED GAMMA TYPE MODEL

    Directory of Open Access Journals (Sweden)

    Vinod Kumar

    2010-01-01

    Full Text Available In the present paper, the maximum likelihood estimates of the two parameters of ageneralized gamma type model have been obtained directly by solving the likelihood equationsas well as by reparametrizing the model first and then solving the likelihood equations (as doneby Prentice, 1974 for fixed values of the third parameter. It is found that reparametrization doesneither reduce the bulk nor the complexity of calculations. as claimed by Prentice (1974. Theprocedure has been illustrated with the help of an example. The distribution of MLE of q alongwith its properties has also been obtained.

  10. The nonhuman primate as a model for type 2 diabetes.

    Science.gov (United States)

    Pound, Lynley D; Kievit, Paul; Grove, Kevin L

    2014-04-01

    Although rodent models provide insight into the mechanisms underlying type 2 diabetes mellitus (T2DM), they are limited in their translatability to humans. The nonhuman primate (NHP) shares important metabolic similarities with the human, making it an ideal model for the investigation of type 2 diabetes and use in preclinical trials. This review highlights the key contributions in the field over the last year using the NHP model. The NHP has not only provided novel insight into the normal and pathological processes that occur within the islet, but has also allowed for the preclinical testing of novel pharmaceutical targets for obesity and T2DM. Particularly, administration of fibroblast growth factor-21 in the NHP resulted in weight loss and improvements in metabolic health, supporting rodent studies and recent clinical trials. In addition, the NHP was used to demonstrate that a novel melanocortin-4 receptor agonist did not cause adverse cardiovascular effects. Finally, this model has been used to provide evidence that glucagon-like peptide-1-based therapies do not induce pancreatitis in the healthy NHP. The insight gained from studies using the NHP model has allowed for a better understanding of the processes driving T2DM and has promoted the development of well tolerated and effective treatments.

  11. Polarization spectral synthesis for Type Ia supernova explosion models

    Science.gov (United States)

    Bulla, M.; Sim, S. A.; Kromer, M.

    2015-06-01

    We present a Monte Carlo radiative transfer technique for calculating synthetic spectropolarimetry for multidimensional supernova explosion models. The approach utilizes `virtual-packets' that are generated during the propagation of the Monte Carlo quanta and used to compute synthetic observables for specific observer orientations. Compared to extracting synthetic observables by direct binning of emergent Monte Carlo quanta, this virtual-packet approach leads to a substantial reduction in the Monte Carlo noise. This is not only vital for calculating synthetic spectropolarimetry (since the degree of polarization is typically very small) but also useful for calculations of light curves and spectra. We first validate our approach via application of an idealized test code to simple geometries. We then describe its implementation in the Monte Carlo radiative transfer code ARTIS and present test calculations for simple models for Type Ia supernovae. Specifically, we use the well-known one-dimensional W7 model to verify that our scheme can accurately recover zero polarization from a spherical model, and to demonstrate the reduction in Monte Carlo noise compared to a simple packet-binning approach. To investigate the impact of aspherical ejecta on the polarization spectra, we then use ARTIS to calculate synthetic observables for prolate and oblate ellipsoidal models with Type Ia supernova compositions.

  12. Ports: Definition and study of types, sizes and business models

    Directory of Open Access Journals (Sweden)

    Ivan Roa

    2013-09-01

    Full Text Available Purpose: In the world today there are thousands of port facilities of different types and sizes, competing to capture some market share of freight by sea, mainly. This article aims to determine the type of port and the most common size, in order to find out which business model is applied in that segment and what is the legal status of the companies of such infrastructure.Design/methodology/approach: To achieve this goal, we develop a research on a representative sample of 800 ports worldwide, which manage 90% of the containerized port loading. Then you can find out the legal status of the companies that manage them.Findings: The results indicate a port type and a dominant size, which are mostly managed by companies subject to a concession model.Research limitations/implications: In this research, we study only those ports that handle freight (basically containerized, ignoring other activities such as fishing, military, tourism or recreational.Originality/value: This is an investigation to show that the vast majority of the studied segment port facilities are governed by a similar corporate model and subject to pressure from the markets, which increasingly demand efficiency and service. Consequently, we tend to concession terminals to private operators in a process that might be called privatization, but in the strictest sense of the term, is not entirely realistic because the ownership of the land never ceases to be public

  13. Vlasov models for kinetic Weibel-type instabilities

    Science.gov (United States)

    Ghizzo, A.; Sarrat, M.; Del Sarto, D.

    2017-02-01

    The Weibel instability, driven by a temperature anisotropy, is investigated within different kinetic descriptions based on the semi-Lagrangian full kinetic and relativistic Vlasov-Maxwell model, on the multi-stream approach, which is based on a Hamiltonian reduction technique, and finally, with the full pressure tensor fluid-type description. Dispersion relations of the Weibel instability are derived using the three different models. A qualitatively different regime is observed in Vlasov numerical experiments depending on the excitation of a longitudinal plasma electric field driven initially by the combined action of the stream symmetry breaking and weak relativistic effects, in contrast with the existing theories of the Weibel instability based on their purely transverse characters. The multi-stream model offers an alternate way to simulate easily the coupling with the longitudinal electric field and particularly the nonlinear regime of saturation, making numerical experiments more tractable, when only a few moments of the distribution are considered. Thus a numerical comparison between the reduced Hamiltonian model (the multi-stream model) and full kinetic (relativistic) Vlasov simulations has been investigated in that regime. Although nonlinear simulations of the fluid model, including the dynamics of the pressure tensor, have not been carried out here, the model is strongly relevant even in the three-dimensional case.

  14. Recent developments in the type IIB matrix model

    CERN Document Server

    Nishimura, Jun

    2014-01-01

    We review recent developments in the type IIB matrix model, which was conjectured to be a nonperturbative formulation of superstring theory. In the first part we review the recent results for the Euclidean model, which suggest that SO(10) symmetry is spontaneously broken. In the second part we review the recent results for the Lorentzian model. In particular, we discuss Monte Carlo results, which suggest that (3+1)-dimensional expanding universe emerges dynamically. We also discuss some results suggesting the emergence of exponential expansion and the power-law expansion at later times. The behaviors at much later times are studied by the classical equation of motion. We discuss a solution representing 3d expanding space, which suggests a possible solution to the cosmological constant problem.

  15. Integrable mixing of A_{n-1} type vertex models

    CERN Document Server

    Grillo, S

    2002-01-01

    Given a family of monodromy matrices {T_u; u=1,...,K} corresponding to integrable anisotropic vertex models of A_{n_u-1}-type, we build up a related mixed vertex model by means of gluing the lattices on which they are defined, in such a way that integrability property is preserved. Algebraically, the gluing process is implemented through one dimensional representations of rectangular matrix algebras A(R_p,R_q), where R_n indicates the R-matrix associated to the standard Hopf algebra deformation of the simple Lie algebra A_{n-1}. We show that algebraic Bethe ansatz can be applied, and the resulting nested equations are identical to the ones corresponding to an A_{n-1} quasi- periodic model with n=min{n_u; u=1,...,K}.

  16. Mouse Models of Type 2 Diabetes Mellitus in Drug Discovery.

    Science.gov (United States)

    Baribault, Helene

    2016-01-01

    Type 2 diabetes is a fast-growing epidemic in industrialized countries, associated with obesity, lack of physical exercise, aging, family history, and ethnic background. Diagnostic criteria are elevated fasting or postprandial blood glucose levels, a consequence of insulin resistance. Early intervention can help patients to revert the progression of the disease together with lifestyle changes or monotherapy. Systemic glucose toxicity can have devastating effects leading to pancreatic beta cell failure, blindness, nephropathy, and neuropathy, progressing to limb ulceration or even amputation. Existing treatments have numerous side effects and demonstrate variability in individual patient responsiveness. However, several emerging areas of discovery research are showing promises with the development of novel classes of antidiabetic drugs.The mouse has proven to be a reliable model for discovering and validating new treatments for type 2 diabetes mellitus. We review here commonly used methods to measure endpoints relevant to glucose metabolism which show good translatability to the diagnostic of type 2 diabetes in humans: baseline fasting glucose and insulin, glucose tolerance test, insulin sensitivity index, and body type composition. Improvements on these clinical values are essential for the progression of a novel potential therapeutic molecule through a preclinical and clinical pipeline.

  17. Modelling of Performance of Caisson Type Breakwaters under Extreme Waves

    Science.gov (United States)

    Güney Doǧan, Gözde; Özyurt Tarakcıoǧlu, Gülizar; Baykal, Cüneyt

    2016-04-01

    Many coastal structures are designed without considering loads of tsunami-like waves or long waves although they are constructed in areas prone to encounter these waves. Performance of caisson type breakwaters under extreme swells is tested in Middle East Technical University (METU) Coastal and Ocean Engineering Laboratory. This paper presents the comparison of pressure measurements taken along the surface of caisson type breakwaters and obtained from numerical modelling of them using IH2VOF as well as damage behavior of the breakwater under the same extreme swells tested in a wave flume at METU. Experiments are conducted in the 1.5 m wide wave flume, which is divided into two parallel sections (0.74 m wide each). A piston type of wave maker is used to generate the long wave conditions located at one end of the wave basin. Water depth is determined as 0.4m and kept constant during the experiments. A caisson type breakwater is constructed to one side of the divided flume. The model scale, based on the Froude similitude law, is chosen as 1:50. 7 different wave conditions are applied in the tests as the wave period ranging from 14.6 s to 34.7 s, wave heights from 3.5 m to 7.5 m and steepness from 0.002 to 0.015 in prototype scale. The design wave parameters for the breakwater were 5m wave height and 9.5s wave period in prototype. To determine the damage of the breakwater which were designed according to this wave but tested under swell waves, video and photo analysis as well as breakwater profile measurements before and after each test are performed. Further investigations are carried out about the acting wave forces on the concrete blocks of the caisson structures via pressure measurements on the surfaces of these structures where the structures are fixed to the channel bottom minimizing. Finally, these pressure measurements will be compared with the results obtained from the numerical study using IH2VOF which is one of the RANS models that can be applied to simulate

  18. Dynamic Modelling of Axle Tramp in a Sport Type Car

    Directory of Open Access Journals (Sweden)

    Ali Zargartalebi

    2013-01-01

    Full Text Available One of the most significant dynamic aspects of coupled vibration of transmission system and dependent type suspension systems is axle tramp. The tramp is defined as undesirable oscillation of rigid live axle around roll axis. In spite of utilizing powerful engines in some type of sport cars, tramp occurrence causes loss of longitudinal performance. The aim of this paper is to derive a mathematical model for predicting and classifying of the tramp. A parameter study reveals that, some parameters such as engine torque, moving parts moment of inertia, car and wheels weight and the material used in suspension system play important role in controlling the tramp. It is shown that large difference between sprung and unsprung mass moment of inertia around the roll-axis, low vehicle mass, short rear track and medium damping values have significant effects on the severity of tramp.

  19. Hair corticosterone measurement in mouse models of type 1 and type 2 diabetes mellitus.

    Science.gov (United States)

    Erickson, Rebecca L; Browne, Caroline A; Lucki, Irwin

    2017-09-01

    In diabetes, glucocorticoid secretion increases secondary to hyperglycemia and is associated with an extensive list of disease complications. Levels of cortisol in humans, or corticosterone in rodents, are usually measured as transitory biomarkers of stress in blood or saliva. Glucocorticoid concentrations accumulate in human or animal hair over weeks and could more accurately measure the cumulative stress burden of diseases like chronic diabetes. In this study, corticosterone levels were measured in hair in verified rodent models of diabetes mellitus. To induce type 1 diabetes, C57BL/6J mice were injected with streptozotocin and blood and hair samples were collected 28days following induction. Leptin receptor deficient (db/db) mice were used as a spontaneous model of type 2 diabetes and blood and hair samples were collected at 8weeks of age, after the development of hyperglycemia and obesity. Corticosterone levels from serum, new growth hair and total growth hair were analyzed using an enzyme immunoassay. Corticosterone levels in new growth hair and serum were significantly elevated in both models of diabetes compared to controls. In contrast, corticosterone levels in old hair growth did not differ significantly between diabetic and non-diabetic animals. Thus, hair removal and sampling of new hair growth was a more sensitive procedure for detecting changes in hair corticosterone levels induced by periods of hyperglycemia lasting for 4weeks in mice. These results validate the use of hair to measure long-term changes in corticosterone induced by diabetes in rodent models. Further studies are now needed to validate the utility of hair cortisol as a tool for measuring the stress burden of individuals with diabetes and for following the effects of long-term medical treatments. Copyright © 2017 Elsevier Inc. All rights reserved.

  20. An Accelerated Radioactive Decay (ARD) Model for Type Ia Supernovae

    Science.gov (United States)

    Rust, Bert W.; Leventhal, Marvin

    2016-01-01

    In 1975, Leventhal and McCall [Nature, 255, 690-692] presented a radioactive decay model 56N i --> 56Co --> 56Fe for the post-peak luminosity decay of Type I supernovae light curves, in which the two decay rates are both accelerated by a common factor. In 1976, Rust, Leventhal and McCall [Nature, 262, 118-120] used sums of exponentials fitting to confirm the acceleration hypothesis, but their result was nevertheless rejected by the astronomical community. Here, we model Type Ia light curves with a system of ODEs (describing the nuclear decays) forced by a Ni-deposition pulse modelled by a 3-parameter Weibull pdf, with all of this occuring in the center of a pre-existing, optically thick, spherical shell which thermalizes the emitted gamma rays. Fitting this model to observed light curves routinely gives fits which account for 99.9+% of the total variance in the observed record. The accelerated decay rates are so stable, for such a long time, that they must occur in an almost unchanging environment -- not it a turbulent expanding atmosphere. The amplitude of the Ni-deposition pulse indicates that its source is the fusion of hydrogen. Carbon and oxygen could not supply the large energy/nucleon that is observed. The secondary peak in the infrared light curve can be easily modelled as a light echo from dust in the back side of the pre-existing shell, and the separation between the peaks indicates a radius of ≈15 light days for the shell. The long-term stability of the acceleration suggests that it is a kinematic effect arising because the nuclear reactions occur either on the surface of a very rapidly rotating condensed object, or in a very tight orbit around such an object, like the fusion pulse in a tokomak reactor.

  1. Future of Plant Functional Types in Terrestrial Biosphere Models

    Science.gov (United States)

    Wullschleger, S. D.; Euskirchen, E. S.; Iversen, C. M.; Rogers, A.; Serbin, S.

    2015-12-01

    Earth system models describe the physical, chemical, and biological processes that govern our global climate. While it is difficult to single out one component as being more important than another in these sophisticated models, terrestrial vegetation is a critical player in the biogeochemical and biophysical dynamics of the Earth system. There is much debate, however, as to how plant diversity and function should be represented in these models. Plant functional types (PFTs) have been adopted by modelers to represent broad groupings of plant species that share similar characteristics (e.g. growth form) and roles (e.g. photosynthetic pathway) in ecosystem function. In this review the PFT concept is traced from its origin in the early 1800s to its current use in regional and global dynamic vegetation models (DVMs). Special attention is given to the representation and parameterization of PFTs and to validation and benchmarking of predicted patterns of vegetation distribution in high-latitude ecosystems. These ecosystems are sensitive to changing climate and thus provide a useful test case for model-based simulations of past, current, and future distribution of vegetation. Models that incorporate the PFT concept predict many of the emerging patterns of vegetation change in tundra and boreal forests, given known processes of tree mortality, treeline migration, and shrub expansion. However, representation of above- and especially belowground traits for specific PFTs continues to be problematic. Potential solutions include developing trait databases and replacing fixed parameters for PFTs with formulations based on trait co-variance and empirical trait-environment relationships. Surprisingly, despite being important to land-atmosphere interactions of carbon, water, and energy, PFTs such as moss and lichen are largely absent from DVMs. Close collaboration among those involved in modelling with the disciplines of taxonomy, biogeography, ecology, and remote sensing will be

  2. Ranking candidate genes in rat models of type 2 diabetes

    Directory of Open Access Journals (Sweden)

    Ståhl Fredrik

    2009-07-01

    Full Text Available Abstract Background Rat models are frequently used to find genomic regions that contribute to complex diseases, so called quantitative trait loci (QTLs. In general, the genomic regions found to be associated with a quantitative trait are rather large, covering hundreds of genes. To help selecting appropriate candidate genes from QTLs associated with type 2 diabetes models in rat, we have developed a web tool called Candidate Gene Capture (CGC, specifically adopted for this disorder. Methods CGC combines diabetes-related genomic regions in rat with rat/human homology data, textual descriptions of gene effects and an array of 789 keywords. Each keyword is assigned values that reflect its co-occurrence with 24 different reference terms describing sub-phenotypes of type 2 diabetes (for example "insulin resistance". The genes are then ranked based on the occurrences of keywords in the describing texts. Results CGC includes QTLs from type 2 diabetes models in rat. When comparing gene rankings from CGC based on one sub-phenotype, with manual gene ratings for four QTLs, very similar results were obtained. In total, 24 different sub-phenotypes are available as reference terms in the application and based on differences in gene ranking, they fall into separate clusters. Conclusion The very good agreement between the CGC gene ranking and the manual rating confirms that CGC is as a reliable tool for interpreting textual information. This, together with the possibility to select many different sub-phenotypes, makes CGC a versatile tool for finding candidate genes. CGC is publicly available at http://ratmap.org/CGC.

  3. A MATHEMATICAL MODEL OF CHP 2000 TYPE PROGRESSIVE GEAR

    Directory of Open Access Journals (Sweden)

    Paweł Lonkwic

    2016-12-01

    Full Text Available The project of CHP2000 type progressive gear has been presented in the article. The offered solution from its construction point of view differs from the existing solutions due to the application of Belleville springs packets supporting the braking roller cam and achieving a flexible range of the gear loading. The standard concept of the gear loading within a mathematical and a geometrical model has been presented in the article. The proposed solution can be used in the friction lifts with the loading capacity from 8500 up to 20000 N.

  4. Manifestation of Instabilities in Nambu-Jona-Lasinio type models

    CERN Document Server

    Hashimoto, M

    2006-01-01

    We study a Nambu-Jona-Lasinio (NJL) type model with two-flavor quark matter in $\\beta$-equilibrium. It turns out that the system develops instabilities in the dispersion relations of the diquark fields, i.e., the velocity squared $v^2$ becomes negative in a certain region of the electron chemical potential. The critical point is the same as that of the chromomagnetic instability. The results imply the existence of spatially inhomogeneous diquark condensates in the genuine vacuum. We also discuss the relation between the homogeneous gluon condensates and the inhomogeneous diquark condensates.

  5. Genetic and Pharmacologic Models for Type 1 Diabetes.

    Science.gov (United States)

    Leiter, Edward H; Schile, Andrew

    2013-03-01

    Type 1 diabetes (T1D) is characterized by a partial or total insufficiency of insulin. The premiere animal model of autoimmune T cell-mediated T1D is the NOD mouse. A dominant negative mutation in the mouse insulin 2 gene (Ins2(Akita) ) produces a severe insulin deficiency syndrome without autoimmune involvement, as do a variety of transgenes overexpressed in beta cells. Pharmacologically-induced T1D (without autoimmunity) elicted by alloxan or streptozotocin at high doses can generate hyperglycemia in almost any strain of mouse by direct toxicity. Multiple low doses of streptozotocin combine direct beta cell toxicity with local inflammation to elicit T1D in a male sex-specific fashion. A summary of protocols relevant to the management of these different mouse models will be covered in this overview.

  6. The first knockin mouse model of episodic ataxia type 2.

    Science.gov (United States)

    Rose, Samuel J; Kriener, Lisa H; Heinzer, Ann K; Fan, Xueliang; Raike, Robert S; van den Maagdenberg, Arn M J M; Hess, Ellen J

    2014-11-01

    Episodic ataxia type 2 (EA2) is an autosomal dominant disorder associated with attacks of ataxia that are typically precipitated by stress, ethanol, caffeine or exercise. EA2 is caused by loss-of-function mutations in the CACNA1A gene, which encodes the α1A subunit of the CaV2.1 voltage-gated Ca(2+) channel. To better understand the pathomechanisms of this disorder in vivo, we created the first genetic animal model of EA2 by engineering a mouse line carrying the EA2-causing c.4486T>G (p.F1406C) missense mutation in the orthologous mouse Cacna1a gene. Mice homozygous for the mutated allele exhibit a ~70% reduction in CaV2.1 current density in Purkinje cells, though surprisingly do not exhibit an overt motor phenotype. Mice hemizygous for the knockin allele (EA2/- mice) did exhibit motor dysfunction measurable by rotarod and pole test. Studies using Cre-flox conditional genetics explored the role of cerebellar Purkinje cells or cerebellar granule cells in the poor motor performance of EA2/- mice and demonstrate that manipulation of either cell type alone did not cause poor motor performance. Thus, it is possible that subtle dysfunction arising from multiple cell types is necessary for the expression of certain ataxia syndromes. Copyright © 2014 Elsevier Inc. All rights reserved.

  7. Modeling fluid dynamics on type II quantum computers

    Science.gov (United States)

    Scoville, James; Weeks, David; Yepez, Jeffrey

    2006-03-01

    A quantum algorithm is presented for modeling the time evolution of density and flow fields governed by classical equations, such as the diffusion equation, the nonlinear Burgers equation, and the damped wave equation. The algorithm is intended to run on a type-II quantum computer, a parallel quantum computer consisting of a lattice of small type I quantum computers undergoing unitary evolution and interacting via information interchanges represented by an orthogonal matrices. Information is effectively transferred between adjacent quantum computers over classical communications channels because of controlled state demolition following local quantum mechanical qubit-qubit interactions within each quantum computer. The type-II quantum algorithm presented in this paper describes a methodology for generating quantum logic operations as a generalization of classical operations associated with finite-point group symmetries. The quantum mechanical evolution of multiple qubits within each node is described. Presented is a proof that the parallel quantum system obeys a finite-difference quantum Boltzman equation at the mesoscopic scale, leading in turn to various classical linear and nonlinear effective field theories at the macroscopic scale depending on the details of the local qubit-qubit interactions.

  8. Modelling of series of types of automated trenchless works tunneling

    Science.gov (United States)

    Gendarz, P.; Rzasinski, R.

    2016-08-01

    Microtunneling is the newest method for making underground installations. Show method is the result of experience and methods applied in other, previous methods of trenchless underground works. It is considered reasonable to elaborate a series of types of construction of tunneling machines, to develop this particular earthworks method. There are many design solutions of machines, but the current goal is to develop non - excavation robotized machine. Erosion machines with main dimensions of the tunnels which are: 1600, 2000, 2500, 3150 are design with use of the computer aided methods. Series of types of construction of tunneling machines creating process was preceded by analysis of current state. The verification of practical methodology of creating the systematic part series was based on the designed erosion machines series of types. There were developed: method of construction similarity of the erosion machines, algorithmic methods of quantitative construction attributes variant analyzes in the I-DEAS advanced graphical program, relational and program parameterization. There manufacturing process of the parts will be created, which allows to verify the technological process on the CNC machines. The models of designed will be modified and the construction will be consulted with erosion machine users and manufacturers like: Tauber Rohrbau GmbH & Co.KG from Minster, OHL ZS a.s. from Brna,. The companies’ acceptance will result in practical verification by JUMARPOL company.

  9. A mouse model for Meckel syndrome type 3.

    Science.gov (United States)

    Cook, Susan A; Collin, Gayle B; Bronson, Roderick T; Naggert, Jürgen K; Liu, Dong P; Akeson, Ellen C; Davisson, Muriel T

    2009-04-01

    Meckel-Gruber syndrome type 3 (MKS3; OMIM 607361) is a severe autosomal recessive disorder characterized by bilateral polycystic kidney disease. Other malformations associated with MKS3 include cystic changes in the liver, polydactyly, and brain abnormalities (occipital encephalocele, hydrocephalus, and Dandy Walker-type cerebellar anomalies). The disorder is hypothesized to be caused by defects in primary cilia. In humans, the underlying mutated gene, TMEM67, encodes transmembrane protein 67, also called meckelin (OMIM 609884), which is an integral protein of the renal epithelial cell and membrane of the primary cilium. Here, we describe a spontaneous deletion of the mouse ortholog, Tmem67, which results in polycystic kidney disease and death by 3 wk after birth. Hydrocephalus also occurs in some mutants. We verified the mutated gene by transgenic rescue and characterized the phenotype with microcomputed tomography, histology, scanning electron microscopy, and immunohistochemistry. This mutant provides a mouse model for MKS3 and adds to the growing set of mammalian models essential for studying the role of the primary cilium in kidney function.

  10. Type II Supernovae: Model Light Curves and Standard Candle Relationships

    Science.gov (United States)

    Kasen, Daniel; Woosley, S. E.

    2009-10-01

    A survey of Type II supernovae explosion models has been carried out to determine how their light curves and spectra vary with their mass, metallicity, and explosion energy. The presupernova models are taken from a recent survey of massive stellar evolution at solar metallicity supplemented by new calculations at subsolar metallicity. Explosions are simulated by the motion of a piston near the edge of the iron core and the resulting light curves and spectra are calculated using full multi-wavelength radiation transport. Formulae are developed that describe approximately how the model observables (light curve luminosity and duration) scale with the progenitor mass, explosion energy, and radioactive nucleosynthesis. Comparison with observational data shows that the explosion energy of typical supernovae (as measured by kinetic energy at infinity) varies by nearly an order of magnitude—from 0.5 to 4.0 × 1051 ergs, with a typical value of ~0.9 × 1051 ergs. Despite the large variation, the models exhibit a tight relationship between luminosity and expansion velocity, similar to that previously employed empirically to make SNe IIP standardized candles. This relation is explained by the simple behavior of hydrogen recombination in the supernova envelope, but we find a sensitivity to progenitor metallicity and mass that could lead to systematic errors. Additional correlations between light curve luminosity, duration, and color might enable the use of SNe IIP to obtain distances accurate to ~20% using only photometric data.

  11. Testing Cosmological Models with Type Ic Super Luminous Supernovae

    CERN Document Server

    Wei, Jun-Jie; Melia, Fulvio

    2015-01-01

    The use of type Ic Super Luminous Supernovae (SLSN Ic) to examine the cosmological expansion introduces a new standard ruler with which to test theoretical models. The sample suitable for this kind of work now includes 11 SLSNe Ic, which have thus far been used solely in tests involving $\\Lambda$CDM. In this paper, we broaden the base of support for this new, important cosmic probe by using these observations to carry out a one-on-one comparison between the $R_{\\rm h}=ct$ and $\\Lambda$CDM cosmologies. We individually optimize the parameters in each cosmological model by minimizing the $\\chi^{2}$ statistic. We also carry out Monte Carlo simulations based on these current SLSN Ic measurements to estimate how large the sample would have to be in order to rule out either model at a $\\sim 99.7\\%$ confidence level. The currently available sample indicates a likelihood of $\\sim$$70-80\\%$ that the $R_{\\rm h}=ct$ Universe is the correct cosmology versus $\\sim$$20-30\\%$ for the standard model. These results are suggest...

  12. Phenomenological Magnetic Model in Tsai-Type Approximants

    Science.gov (United States)

    Sugimoto, Takanori; Tohyama, Takami; Hiroto, Takanobu; Tamura, Ryuji

    Recent neutron diffraction study has reported a curious ferromagnetism in Tsai-type approximants Au-Si-RE (RE=Tb,Dy,Ho), which have the same local structure as quasi-crystals with a translational symmetry simultaneously. In these materials, magnetic moments of rare-earth atoms have a single-ion anisotropy determined locally via spin-orbit coupling around crystal fields satisfying a distorted icosahedral crystal structure. We phenomenologically propose a possible magnetic model reproducing the magnetic structure and the thermodynamical quantities. The corresponding energies of the single-ion anisotropy and RKKY exchange couplings are also estimated by comparing magnetization curves and susceptibility of our model and experiments. Moreover, simulated annealing calculations with the energies in our model coincide with the strange ferromagnetism. In conclusion, a distortion of icosahedral cluster in body-centered cubic structure plays a key role to emerge the peculiar magnetic structure. Our magnetic model does not only explain magnetic behaviors in quasi-crystal approximants, but also can approach to a coexistence of a long-ranged order and a quasi-periodicity.

  13. Structural Equation Modeling of Multitrait-Multimethod Data: Different Models for Different Types of Methods

    Science.gov (United States)

    Eid, Michael; Nussbeck, Fridtjof W.; Geiser, Christian; Cole, David A.; Gollwitzer, Mario; Lischetzke, Tanja

    2008-01-01

    The question as to which structural equation model should be selected when multitrait-multimethod (MTMM) data are analyzed is of interest to many researchers. In the past, attempts to find a well-fitting model have often been data-driven and highly arbitrary. In the present article, the authors argue that the measurement design (type of methods…

  14. Plant functional type mapping for earth system models

    Directory of Open Access Journals (Sweden)

    B. Poulter

    2011-08-01

    Full Text Available The sensitivity of global carbon and water cycling to climate variability is coupled directly to land cover and the distribution of vegetation. To investigate biogeochemistry-climate interactions, earth system models require a representation of vegetation distributions that are either prescribed from remote sensing data or simulated via biogeography models. However, the abstraction of earth system state variables in models means that data products derived from remote sensing need to be post-processed for model-data assimilation. Dynamic global vegetation models (DGVM rely on the concept of plant functional types (PFT to group shared traits of thousands of plant species into just several classes. Available databases of observed PFT distributions must be relevant to existing satellite sensors and their derived products, and to the present day distribution of managed lands. Here, we develop four PFT datasets based on land-cover information from three satellite sensors (EOS-MODIS 1 km and 0.5 km, SPOT4-VEGETATION 1 km, and ENVISAT-MERIS 0.3 km spatial resolution that are merged with spatially-consistent Köppen-Geiger climate zones. Using a beta (β diversity metric to assess reclassification similarity, we find that the greatest uncertainty in PFT classifications occur most frequently between cropland and grassland categories, and in dryland systems between shrubland, grassland and forest categories because of differences in the minimum threshold required for forest cover. The biogeography-biogeochemistry DGVM, LPJmL, is used in diagnostic mode with the four PFT datasets prescribed to quantify the effect of land-cover uncertainty on climatic sensitivity of gross primary productivity (GPP and transpiration fluxes. Our results show that land-cover uncertainty has large effects in arid regions, contributing up to 30 % (20 % uncertainty in the sensitivity of GPP (transpiration to precipitation. The availability of plant functional type datasets that

  15. A Type-Token Identity in the Simon-Yule Model of Text.

    Science.gov (United States)

    Chen, Ye-Sho; Leimkuhler, Ferdinand F.

    1989-01-01

    Establishes a type-token identity relating type-token ratio and bilogarithmic type-token ratio; uses the Simon-Yule model of Zipf's law to drive the type-token ratio and provide a statistical model of text generation; and refines the model to allow for decreasing entry rates of new words. (26 references) (Author/CLB)

  16. Models for dose assessments. Modules for various biosphere types

    Energy Technology Data Exchange (ETDEWEB)

    Bergstroem, U.; Nordlinder, S.; Aggeryd, I. [Studsvik Eco and Safety AB, Nykoeping (Sweden)

    1999-12-01

    The main objective of this study was to provide a basis for illustrations of yearly dose rates to the most exposed individual from hypothetical leakages of radionuclides from a deep bedrock repository for spent nuclear fuel and other radioactive waste. The results of this study will be used in the safety assessment SR 97 and in a study on the design and long-term safety for a repository planned to contain long-lived low and intermediate level waste. The repositories will be designed to isolate the radionuclides for several hundred thousands of years. In the SR 97 study, however, hypothetical scenarios for leakage are postulated. Radionuclides are hence assumed to be transported in the geosphere by groundwater, and probably discharge into the biosphere. This may occur in several types of ecosystems. A number of categories of such ecosystems were identified, and turnover of radionuclides was modelled separately for each ecosystem. Previous studies had focused on generic models for wells, lakes and coastal areas. These models were, in this study, developed further to use site-specific data. In addition, flows of groundwater, containing radionuclides, to agricultural land and peat bogs were considered. All these categories are referred to as modules in this report. The forest ecosystems were not included, due to a general lack of knowledge of biospheric processes in connection with discharge of groundwater in forested areas. Examples of each type of module were run with the assumption of a continuous annual release into the biosphere of 1 Bq for each radionuclide during 10 000 years. The results are presented as ecosystem specific dose conversion factors (EDFs) for each nuclide at the year 10 000, assuming stationary ecosystems and prevailing living conditions and habits. All calculations were performed with uncertainty analyses included. Simplifications and assumptions in the modelling of biospheric processes are discussed. The use of modules may be seen as a step

  17. Neutrino event counts from Type Ia supernova models

    Science.gov (United States)

    Nagaraj, Gautam; Scholberg, Kate

    2016-01-01

    Core collapse supernovae (SNe) are widely known to be among the universe's primary neutrino factories, releasing ˜99% of their energy, or ˜1053 ergs, in the form of the tiny leptons. On the other hand, less than 4% of the energy of Type Ia SNe is released via neutrinos, hence making Ia SNe impossible to detect (through neutrino observations) at typical supernova distances. For this reason, neutrino signatures from these explosions have very rarely been modeled. We ran time-sliced fluences from non-oscillation pure deflagration and delayed detonation (DDT) Ia models by Odrzywolek and Plewa (2011) through SNOwGLoBES, a software that calculates event rates and other observed quantities of supernova neutrinos in various detectors. We determined Ia neutrino event rates in Hyper-K, a proposed water Cherenkov detector, JUNO, a scintillator detector under construction, and DUNE, a proposed argon detector, and identified criteria to distinguish between the two models (pure deflagration and DDT) based on data from a real supernova (statistically represented by a Poisson distribution around the expected result). We found that up to distances of 8.00, 1.54, and 2.37 kpc (subject to change based on oscillation effects and modified detector efficiencies), we can discern the explosion mechanism with ≥90% confidence in Hyper-K, JUNO, and DUNE, respectively, thus learning more about Ia progenitors.

  18. Radiative Type III Seesaw Model and its collider phenomenology

    CERN Document Server

    von der Pahlen, Federico; Restrepo, Diego; Zapata, Oscar

    2016-01-01

    We analyze the present bounds of a scotogenic model, the Radiative Type III Seesaw (RSIII), in which an additional scalar doublet and at least two fermion triplets of $SU(2)_L$ are added to the Standard Model (SM). In the RSIII the new physics (NP) sector is odd under an exact global $Z_2$ symmetry. This symmetry guaranties that the lightest NP neutral particle is stable, providing a natural dark matter (DM) candidate, and leads to naturally suppressed neutrino masses generated by a one-loop realization of an effective Weinberg operator. We focus on the region with the highest sensitivity in present and future LHC searches, with light scalar DM and at least one NP fermion triplet at the sub-TeV scale. This region allows for significant production cross-sections of NP fermion pairs at the LHC. We reinterpret a set of searches for supersymmetric particles at the LHC obtained using the package CheckMATE, to set limits on our model as a function of the masses of the NP particles and their Yukawa interactions. The...

  19. A Strip-Type Microthrottle Pump: Modeling, Design and Fabrication

    Directory of Open Access Journals (Sweden)

    Dejan Križaj

    2013-03-01

    Full Text Available A novel design for a strip-type microthrottle pump with a rectangular actuator geometry is proposed, with more efficient chip surface consumption compared to existing micropumps with circular actuators. Due to the complex structure and operation of the proposed device, determination of detailed structural parameters is essential. Therefore, we developed an advanced, fully coupled 3D electro-fluid-solid mechanics simulation model in COMSOL that includes fluid inertial effects and a hyperelastic model for PDMS and no-slip boundary condition in fluid-wall interface. Numerical simulation resulted in accurate virtual prototyping of the proposed device only after inclusion of all mentioned effects. Here, we provide analysis of device operation at various frequencies which describes the basic pumping effects, role of excitation amplitude and backpressure and provides optimization of critical design parameters such as optimal position and height of the microthrottles. Micropump prototypes were then fabricated and characterized. Measured characteristics proved expected micropump operation, achieving maximal flow-rate 0.43 mL·min−1 and maximal backpressure 12.4 kPa at 300 V excitation. Good agreement between simulation and measurements on fabricated devices confirmed the correctness of the developed simulation model.

  20. Impact of model structure and parameterization on Penman-Monteith type evaporation models

    KAUST Repository

    Ershadi, A.

    2015-04-12

    The impact of model structure and parameterization on the estimation of evaporation is investigated across a range of Penman-Monteith type models. To examine the role of model structure on flux retrievals, three different retrieval schemes are compared. The schemes include a traditional single-source Penman-Monteith model (Monteith, 1965), a two-layer model based on Shuttleworth and Wallace (1985) and a three-source model based on Mu et al. (2011). To assess the impact of parameterization choice on model performance, a number of commonly used formulations for aerodynamic and surface resistances were substituted into the different formulations. Model response to these changes was evaluated against data from twenty globally distributed FLUXNET towers, representing a cross-section of biomes that include grassland, cropland, shrubland, evergreen needleleaf forest and deciduous broadleaf forest. Scenarios based on 14 different combinations of model structure and parameterization were ranked based on their mean value of Nash-Sutcliffe Efficiency. Results illustrated considerable variability in model performance both within and between biome types. Indeed, no single model consistently outperformed any other when considered across all biomes. For instance, in grassland and shrubland sites, the single-source Penman-Monteith model performed the best. In croplands it was the three-source Mu model, while for evergreen needleleaf and deciduous broadleaf forests, the Shuttleworth-Wallace model rated highest. Interestingly, these top ranked scenarios all shared the simple lookup-table based surface resistance parameterization of Mu et al. (2011), while a more complex Jarvis multiplicative method for surface resistance produced lower ranked simulations. The highly ranked scenarios mostly employed a version of the Thom (1975) formulation for aerodynamic resistance that incorporated dynamic values of roughness parameters. This was true for all cases except over deciduous broadleaf

  1. Exploring a type-theoretic approach to accessibility constraint modelling

    CERN Document Server

    Pogodalla, Sylvain

    2008-01-01

    The type-theoretic modelling of DRT that [degroote06] proposed features continuations for the management of the context in which a clause has to be interpreted. This approach, while keeping the standard definitions of quantifier scope, translates the rules of the accessibility constraints of discourse referents inside the semantic recipes. In this paper, we deal with additional rules for these accessibility constraints. In particular in the case of discourse referents introduced by proper nouns, that negation does not block, and in the case of rhetorical relations that structure discourses. We show how this continuation-based approach applies to those accessibility constraints and how we can consider the parallel management of various principles.

  2. Euclidean 4d exact solitons in a Skyrme type model

    Energy Technology Data Exchange (ETDEWEB)

    Ferreira, L.A. [Instituto de Fisica de Sao Carlos, IFSC/USP, Universidade de Sao Paulo, Caixa Postal 369, CEP 13560-970 Sao Carlos, SP (Brazil) and Instituto de Fisica Teorica, IFT/UNESP, Universidade Estadula Paulista, Rua Pamplona 145, 01405-900 Sao Paulo, SP (Brazil)]. E-mail: laf@if.sc.usp.br

    2005-01-27

    We introduce a Skyrme type, four-dimensional Euclidean field theory made of a triplet of scalar fields n->, taking values on the sphere S{sup 2}, and an additional real scalar field {phi}, which is dynamical only on a three-dimensional surface embedded in R{sup 4}. Using a special ansatz we reduce the 4d non-linear equations of motion into linear ordinary differential equations, which lead to the construction of an infinite number of exact soliton solutions with vanishing Euclidean action. The theory possesses a mass scale which fixes the size of the solitons in way which differs from Derrick's scaling arguments. The model may be relevant to the study of the low energy limit of pure SU(2) Yang-Mills theory.

  3. Affleck-Dine Baryogenesis in Type IIB String Models

    CERN Document Server

    Allahverdi, Rouzbeh; Muia, Francesco

    2016-01-01

    We present a viable string embedding of Affleck-Dine baryogenesis in type IIB sequestered models where the late-time decay of the lightest modulus reheats the universe to relatively low temperatures. We show that if inflation is driven by a blow-up Kaehler modulus, the Affleck-Dine field can become tachyonic during inflation if the Kaehler metric for matter fields has an appropriate inflaton-dependent contribution. We find that the Affleck-Dine mechanism can generate the observed baryon asymmetry for natural values of the underlying parameters which lead also to successful inflation and low-energy gaugino masses in a split supersymmetry scenario. The reheating temperature from the lightest modulus decay is high enough to allow thermal Higgsino-like dark matter.

  4. Affleck-Dine baryogenesis in type IIB string models

    Science.gov (United States)

    Allahverdi, Rouzbeh; Cicoli, Michele; Muia, Francesco

    2016-06-01

    We propose a possible string embedding of Affleck-Dine baryogenesis in type IIB sequestered models where the late-time decay of the lightest modulus reheats the universe to relatively low temperatures. We show that if inflation is driven by a blow-up Kähler modulus, the Affleck-Dine field can become tachyonic during inflation if the Kähler metric for matter fields has an appropriate inflaton-dependent contribution. We find that the Affleck-Dine mechanism can generate the observed baryon asymmetry for natural values of the underlying parameters which lead also to successful inflation and low-energy gaugino masses in a split supersymmetry scenario. The reheating temperature from the lightest modulus decay is high enough to allow thermal Higgsino-like dark matter.

  5. Renal histopathology of a baboon model with type 2 diabetes.

    Science.gov (United States)

    Rincon-Choles, Hernan; Abboud, Hanna E; Lee, Shuko; Shade, Robert E; Rice, Karen S; Carey, K Dee; Comuzzie, Anthony G; Barnes, Jeffrey L

    2012-10-01

    Naturally occurring type 2 diabetes has been found in a colony of baboons. Ongoing characterization of the baboon colony maintained at the Southwest National Primate Research Center has revealed a significant range of glucose sensitivity with some animals clearly diabetic.   Seven baboons, four with diabetes and three without diabetes, underwent histopathological investigation. Three diabetic animals were diagnosed using fasting blood glucose, hemoglobin A1C, and intravenous glucose tolerance test, and a fourth one was known to have hyperglycemia. One control baboon and three baboons with diabetes had microalbuminuria. On kidney biopsy, diabetic baboons had thickening of the glomerular basement membrane and mesangial matrix expansion compared to controls. Immunohistochemistry showed the diabetic animals had increased mesangial expression of cellular fibronectin ED-A. Two diabetic animals with microalbuminuria had evidence of mesangiolysis with the formation of an early nodule. One diabetic animal had a Kimmestiel-Wilson nodule. We conclude that the baboon represents a useful primate model of diabetes and nephropathy that resembles the nephropathy associated with type 2 diabetes in humans.

  6. Plant functional type mapping for earth system models

    Directory of Open Access Journals (Sweden)

    B. Poulter

    2011-11-01

    Full Text Available The sensitivity of global carbon and water cycling to climate variability is coupled directly to land cover and the distribution of vegetation. To investigate biogeochemistry-climate interactions, earth system models require a representation of vegetation distributions that are either prescribed from remote sensing data or simulated via biogeography models. However, the abstraction of earth system state variables in models means that data products derived from remote sensing need to be post-processed for model-data assimilation. Dynamic global vegetation models (DGVM rely on the concept of plant functional types (PFT to group shared traits of thousands of plant species into usually only 10–20 classes. Available databases of observed PFT distributions must be relevant to existing satellite sensors and their derived products, and to the present day distribution of managed lands. Here, we develop four PFT datasets based on land-cover information from three satellite sensors (EOS-MODIS 1 km and 0.5 km, SPOT4-VEGETATION 1 km, and ENVISAT-MERIS 0.3 km spatial resolution that are merged with spatially-consistent Köppen-Geiger climate zones. Using a beta (ß diversity metric to assess reclassification similarity, we find that the greatest uncertainty in PFT classifications occur most frequently between cropland and grassland categories, and in dryland systems between shrubland, grassland and forest categories because of differences in the minimum threshold required for forest cover. The biogeography-biogeochemistry DGVM, LPJmL, is used in diagnostic mode with the four PFT datasets prescribed to quantify the effect of land-cover uncertainty on climatic sensitivity of gross primary productivity (GPP and transpiration fluxes. Our results show that land-cover uncertainty has large effects in arid regions, contributing up to 30% (20% uncertainty in the sensitivity of GPP (transpiration to precipitation. The availability of PFT datasets that are consistent

  7. Gas entrainment in scaled model of pool type LMFBR

    Energy Technology Data Exchange (ETDEWEB)

    Banerjee, I.; Chandra, L.; Laxman, D.; Kumar, A.; Gopal, C.A.; Shivakumar, N.S.; Padmakumar, G.; Anand Babu, C.; Vaidyanathan, G. [Fast Reactor Technology Group, Indira Gandhi Centre for Atomic Research, Kalpakkam, Tamil Nadu (India)

    2007-07-01

    The reactor Thermal hydraulics plays an important role for successful operation of Prototype Fast Breeder Reactor (PFBR), which is under construction at Kalpakkam, India. One of the issues to be resolved in PFBR is argon cover gas entrainment problem from free liquid sodium surface. The entrained cover gas may hinder the normal reactor operation. High free surface velocity along with the presence of various immersed components in the hot pool is the cause of gas entrainment from free surface. To reduce the free surface velocity and hence gas entrainment, ring type baffle plates were considered. Initially the optimum geometry of the baffle plate was arrived through numerical analysis using PHOENICS, a commercial computational fluid dynamics tool. Finally the experiments were conducted in a 1/4 scale water model of PFBR primary circuit with selected baffle plate geometry. It was found that a baffle plate with radial width of 125 mm in the model and located above intermediate heat exchanger is very effective to reduce the gas entrainment problem in PFBR. (authors)

  8. Carbon Deflagration in Type Ia Supernova: I. Centrally Ignited Models

    CERN Document Server

    Ma, H; Malone, C M; Almgren, A; Bell, J B

    2013-01-01

    A leading model for Type Ia supernovae (SNe Ia) begins with a white dwarf near the Chandrasekhar mass that ignites a degenerate thermonuclear runaway close to its center and explodes. In a series of papers, we shall explore the consequences of ignition at several locations within such dwarfs. Here we assume central ignition, which has been explored before, however, the problem is worth revisiting, if only to validate those previous studies and to further elucidate the relevant physics for future work. A perturbed sphere of hot iron ash with a radius of ~100 km is initialized at the middle of the star. The subsequent explosion is followed in several simulations using a thickened flame model in which the flame speed is either fixed --- within the range expected from turbulent combustion --- or based on the local turbulent intensity. Global results, including the explosion energy and bulk nucleosynthesis (e.g. 56Ni of 0.48--0.56 $\\Msun$) turn out to be insensitive to this speed. In all completed runs, the energy...

  9. Fluctuating selection models and McDonald-Kreitman type analyses.

    Directory of Open Access Journals (Sweden)

    Toni I Gossmann

    Full Text Available It is likely that the strength of selection acting upon a mutation varies through time due to changes in the environment. However, most population genetic theory assumes that the strength of selection remains constant. Here we investigate the consequences of fluctuating selection pressures on the quantification of adaptive evolution using McDonald-Kreitman (MK style approaches. In agreement with previous work, we show that fluctuating selection can generate evidence of adaptive evolution even when the expected strength of selection on a mutation is zero. However, we also find that the mutations, which contribute to both polymorphism and divergence tend, on average, to be positively selected during their lifetime, under fluctuating selection models. This is because mutations that fluctuate, by chance, to positive selected values, tend to reach higher frequencies in the population than those that fluctuate towards negative values. Hence the evidence of positive adaptive evolution detected under a fluctuating selection model by MK type approaches is genuine since fixed mutations tend to be advantageous on average during their lifetime. Never-the-less we show that methods tend to underestimate the rate of adaptive evolution when selection fluctuates.

  10. Hydrodynamical models of Type II-Plateau Supernovae

    CERN Document Server

    Bersten, Melina C; Hamuy, Mario

    2011-01-01

    We present bolometric light curves of Type II-plateau supernovae (SNe II-P) obtained using a newly developed, one-dimensional Lagrangian hydrodynamic code with flux-limited radiation diffusion. Using our code we calculate the bolometric light curve and photospheric velocities of SN1999em obtaining a remarkably good agreement with observations despite the simplifications used in our calculation. The physical parameters used in our calculation are E=1.25 foe, M= 19 M_\\odot, R= 800 R_\\odot and M_{Ni}=0.056 M_\\odot. We find that an extensive mixing of 56Ni is needed in order to reproduce a plateau as flat as that shown by the observations. We also study the possibility to fit the observations with lower values of the initial mass consistently with upper limits that have been inferred from pre-supernova imaging of SN1999em in connection with stellar evolution models. We cannot find a set of physical parameters that reproduce well the observations for models with pre-supernova mass of \\leq 12 M_\\odot, although mode...

  11. Another New Solvable Many-Body Model of Goldfish Type

    Directory of Open Access Journals (Sweden)

    Francesco Calogero

    2012-07-01

    Full Text Available A new solvable many-body problem is identified. It is characterized by nonlinear Newtonian equations of motion (''acceleration equal force'' featuring one-body and two-body velocity-dependent forces ''of goldfish type'' which determine the motion ofan arbitrary number $N$ of unit-mass point-particles in a plane. The $N$ (generally complex values $z_{n}(t$ at time $t$ ofthe $N$ coordinates of these moving particles are given by the $N$eigenvalues of a time-dependent $Nimes N$ matrix $U(t$explicitly known in terms of the $2N$ initial data $z_{n}(0$and $dot{z}_{n}(0 $. This model comes in two dif/ferentvariants, one featuring 3 arbitrary coupling constants, the other only 2; for special values of these parameters all solutions are completely periodic with the same period independent of the initial data (''isochrony''; for other special values of these parameters this property holds up to corrections vanishing exponentially as $tightarrow infty$ (''asymptotic isochrony''. Other isochronous variants of these models are also reported. Alternative formulations, obtained by changing the dependent variables from the $N$ zeros of a monic polynomial of degree $N$ to its $N$ coefficients, are also exhibited. Some mathematical findings implied by some of these results - such as Diophantine properties of the zeros of certain polynomials - are outlined, but their analysis is postponed to a separate paper.

  12. Radiation-hydrodynamical modelling of underluminous type II plateau Supernovae

    CERN Document Server

    Pumo, M L; Spiro, S; Pastorello, A; Benetti, S; Cappellaro, E; Manicò, G; Turatto, M

    2016-01-01

    With the aim of improving our knowledge about the nature of the progenitors of low-luminosity Type II plateau supernovae (LL SNe IIP), we made radiation-hydrodynamical models of the well-sampled LL SNe IIP 2003Z, 2008bk and 2009md. For these three SNe we infer explosion energies of $0.16$-$0.18$ foe, radii at explosion of $1.8$-$3.5 \\times 10^{13}$ cm, and ejected masses of $10$-$11.3$\\Msun. The estimated progenitor mass on the main sequence is in the range $\\sim 13.2$-$15.1$\\Msun\\, for SN 2003Z and $\\sim 11.4$-$12.9$\\Msun\\, for SNe 2008bk and 2009md, in agreement with estimates from observations of the progenitors. These results together with those for other LL SNe IIP modelled in the same way, enable us also to conduct a comparative study on this SN sub-group. The results suggest that: a) the progenitors of faint SNe IIP are slightly less massive and have less energetic explosions than those of intermediate-luminosity SNe IIP, b) both faint and intermediate-luminosity SNe IIP originate from low-energy explo...

  13. Dynamical Model for Spindown of Solar-type Stars

    Science.gov (United States)

    Sood, Aditi; Kim, Eun-jin; Hollerbach, Rainer

    2016-12-01

    After their formation, stars slow down their rotation rates by the removal of angular momentum from their surfaces, e.g., via stellar winds. Explaining how this rotation of solar-type stars evolves in time is currently an interesting but difficult problem in astrophysics. Despite the complexity of the processes involved, a traditional model, where the removal of angular momentum by magnetic fields is prescribed, has provided a useful framework to understand observational relations between stellar rotation, age, and magnetic field strength. Here, for the first time, a spindown model is proposed where loss of angular momentum by magnetic fields evolves dynamically, instead of being prescibed kinematically. To this end, we evolve the stellar rotation and magnetic field simultaneously over stellar evolution time by extending our previous work on a dynamo model which incorporates nonlinear feedback mechanisms on rotation and magnetic fields. We show that our extended model reproduces key observations and is capable of explaining the presence of the two branches of (fast and slow rotating) stars which have different relations between rotation rate Ω versus time (age), magnetic field strength | B| versus rotation rate, and frequency of magnetic field {ω }{cyc} versus rotation rate. For fast rotating stars we find that: (i) there is an exponential spindown {{Ω }}\\propto {e}-1.35t, with t measured in Gyr; (ii) magnetic activity saturates for higher rotation rate; (iii) {ω }{cyc}\\propto {{{Ω }}}0.83. For slow rotating stars we find: (i) a power-law spindown {{Ω }}\\propto {t}-0.52; (ii) that magnetic activity scales roughly linearly with rotation rate; (iii) {ω }{cyc}\\propto {{{Ω }}}1.16. The results obtained from our investigations are in good agreement with observations. The Vaughan-Preston gap is consistently explained in our model by the shortest spindown timescale in this transition from fast to slow rotators. Our results highlight the importance of self

  14. MATHEMATICAL MODEL OF RR-TYPE MICROMECHANICAL GYRO CAPACITIVE COMB-TYPE SENSORS WITH ACCOUNT FOR VIBRATIONS

    Directory of Open Access Journals (Sweden)

    M. I. Evstifeev

    2016-05-01

    Full Text Available Subject of Research.The reasons for subharmonic resonances in RR-type micromechanical gyro output under linear vibrations are investigated. In ideal case, this type of gyro should be insensitive to this kind of impact due to primary and secondary angular oscillations. However, experimental results reveal significant increase in output signal under external vibrations in 20 Hz - 2 kHz bandwidth, though the device natural frequencies are above 3 kHz. This effect is caused by characteristicsnonlinearity of plate-type and comb-type capacitive sensors. Method. Mathematical model of the capacitive comb-type sensors is clarified. Electromechanical interactions in the sensors under external vibrations are described. Simulink modeling of specified mathematical model is carried out. External vibration modeling is doneby “oscillating frequency” method with constant accelerationamplitude in 20 Hz - 2 kHz bandwidth. Main Results.We have received good agreement of modeling and experimental results in the form of occurrence of subharmonic resonances under linear vibrations in three orthogonal directions. Obtained effects are explained by proposed mathematical models. The main reason for subharmonic resonances in RR-type micromechanical gyro output is that combs of stator and combs of proof mass jump out of mesh. Practical Relevance. The provided investigation gives the possibility to determine algorithmic and construction compensation methods of studied interactions for enhancing vibration resistance of RR-type micromechanical gyro.

  15. What causes type 1 diabetes? Lessons from animal models.

    Science.gov (United States)

    Buschard, Karsten

    2011-07-01

    To study type 1 diabetes (T1D), excellent animal models exist, both spontaneously diabetic and virus-induced. Based on knowledge from these, this review focuses on the environmental factors leading to T1D, concentrated into four areas which are: (1) The thymus-dependent immune system: T1D is a T cell driven disease and the beta cells are destroyed in an inflammatory insulitis process. Autoimmunity is breakdown of self-tolerance and the balance between regulator T cells and aggressive effector T cells is disturbed. Inhibition of the T cells (by e.g. anti-CD3 antibody or cyclosporine) will stop the T1D process, even if initiated by virus. Theoretically, the risk from immunotherapy elicits a higher frequency of malignancy. (2) The activity of the beta cells: Resting beta cells display less antigenicity and are less sensitive to immune destruction. Beta-cell rest can be induced by giving insulin externally in metabolic doses or by administering potassium-channel openers. Both procedures prevent T1D in animal models, whereas no good human data exist due to the risk of hypoglycemia. (3) NKT cells: According to the hygiene hypothesis, stimulation of NKT cells by non-pathogen microbes gives rise to less T cell reaction and less autoimmunity. Glycolipids presented by CD1 molecules are central in this stimulation. (4) Importance of the intestine and gliadin intake: Gluten-free diet dramatically inhibits T1D in animal models, and epidemiological data are supportive of such an effect in humans. The mechanisms include less subclinical intestinal inflammation and permeability, and changed composition of bacterial flora, which can also be obtained by intake of probiotics. Gluten-free diet is difficult to implement, and short-term intake has no effect. Regarding the onset of the T1D disease process, slow-acting enterovirus and gliadin deposits are speculated to be etiological in genetically susceptible individuals, followed by the mentioned four pathogenetic factors acting in

  16. Radiation-hydrodynamical modelling of underluminous Type II plateau supernovae

    Science.gov (United States)

    Pumo, M. L.; Zampieri, L.; Spiro, S.; Pastorello, A.; Benetti, S.; Cappellaro, E.; Manicò, G.; Turatto, M.

    2017-01-01

    With the aim of improving our knowledge about the nature of the progenitors of low-luminosity Type II plateau supernovae (LL SNe IIP), we made radiation-hydrodynamical models of the well-sampled LL SNe IIP 2003Z, 2008bk and 2009md. For these three SNe, we infer explosion energies of 0.16-0.18 foe, radii at explosion of 1.8-3.5 × 1013 cm and ejected masses of 10-11.3 M⊙. The estimated progenitor mass on the main sequence is in the range ˜13.2-15.1 M⊙ for SN 2003Z and ˜11.4-12.9 M⊙ for SNe 2008bk and 2009md, in agreement with estimates from observations of the progenitors. These results together with those for other LL SNe IIP modelled in the same way enable us also to conduct a comparative study on this SN sub-group. The results suggest that (a) the progenitors of faint SNe IIP are slightly less massive and have less energetic explosions than those of intermediate-luminosity SNe IIP; (b) both faint and intermediate-luminosity SNe IIP originate from low-energy explosions of red (or yellow) supergiant stars of low to intermediate mass; (c) some faint objects may also be explained as electron-capture SNe from massive super-asymptotic giant branch stars; and (d) LL SNe IIP form the underluminous tail of the SNe IIP family, where the main parameter `guiding' the distribution seems to be the ratio of the total explosion energy to the ejected mass. Further hydrodynamical studies should be performed and compared to a more extended sample of LL SNe IIP before drawing any conclusion on the relevance of fall-back to this class of events.

  17. On type B cyclogenesis in a quasi-geostrophic model

    Science.gov (United States)

    Grotjahn, Richard

    2005-01-01

    A quasi-geostrophic (QG) model is used to approximate some aspects of 'type B' cyclogenesis as described in an observational paper that appeared several decades earlier in this journal. Though often cited, that earlier work has some ambiguity that has propagated into subsequent analyses. The novel aspects examined here include allowing advective nonlinearity to distort and amplify structures that are quasi-coherent and nearly stable in a linear form of the model; also, separate upper and lower structures are localized in space. Cases are studied separately where the upper trough tracks across different low-level features: an enhanced baroclinic zone (stronger horizontal temperature gradient) or a region of augmented temperature. Growth by superposition of lower and upper features is excluded by experimental design. The dynamics are evaluated with the vertical motion equation, the QG vorticity equation, the QG perturbation energy equation, and 'potential-vorticity thinking'. Results are compared against 'control' cases having no additional low-level features. Nonlinearity is examined relative to a corresponding linear calculation and is generally positive. The results are perhaps richer than the seminal article might imply, because growth is enhanced not only when properties of the lower feature reinforce growth but also when the lower feature opposes decay of the upper feature. For example, growth is enhanced where low-level warm advection introduces rising warm air to oppose the rising cold air ahead of the upper trough. Such growth is magnified when adjacent warm and cold anomalies have a strong baroclinic zone between them. The enhanced growth triggers an upstream tilt in the solution whose properties further accelerate the growth.

  18. Model-based Type B uncertainty evaluations of measurement towards more objective evaluation strategies

    NARCIS (Netherlands)

    M. Boumans

    2013-01-01

    This article proposes a more objective Type B evaluation. This can be achieved when Type B uncertainty evaluations are model-based. This implies, however, grey-box modelling and validation instead of white-box modelling and validation which are appropriate for Type A evaluation.

  19. Dystrophic spinal deformities in a neurofibromatosis type 1 murine model.

    Directory of Open Access Journals (Sweden)

    Steven D Rhodes

    Full Text Available Despite the high prevalence and significant morbidity of spinal anomalies in neurofibromatosis type 1 (NF1, the pathogenesis of these defects remains largely unknown. Here, we present two murine models: Nf1flox/-;PeriCre and Nf1flox/-;Col.2.3Cre mice, which recapitulate spinal deformities seen in the human disease. Dynamic histomorphometry and microtomographic studies show recalcitrant bone remodeling and distorted bone microarchitecture within the vertebral spine of Nf1flox/-;PeriCre and Nf1flox/-;Col2.3Cre mice, with analogous histological features present in a human patient with dystrophic scoliosis. Intriguingly, 36-60% of Nf1flox/-;PeriCre and Nf1flox/-;Col2.3Cre mice exhibit segmental vertebral fusion anomalies with boney obliteration of the intervertebral disc (IVD. While analogous findings have not yet been reported in the NF1 patient population, we herein present two case reports of IVD defects and interarticular vertebral fusion in patients with NF1. Collectively, these data provide novel insights regarding the pathophysiology of dystrophic spinal anomalies in NF1, and provide impetus for future radiographic analyses of larger patient cohorts to determine whether IVD and vertebral fusion defects may have been previously overlooked or underreported in the NF1 patient population.

  20. Mathematical model of various statements of C-type Language

    Directory of Open Access Journals (Sweden)

    Manoj Kumar Srivastav

    2013-12-01

    Full Text Available Some of the important components of high level languages are statements, keywords, variable declarations, arrays, user defined functions etc. In case of object oriented programming language we use class, object, inheritance, operator overloading, function overloading, polymorphism etc. There are some common category of statements such as control statement, loop statements etc. Pointers are also one important concept in C-language. User defined functions, function subprograms or subroutines are also important concepts in different programming languages. The language like ALGOL was developed using Chomsky context free grammar. The similar concept used in C-type languages. The high level languages are now based on mathematical derivations and logic. Most of the components of any high level language can be obtained from simple mathematical logic and derivations. In the present study the authors have tried to give some unified mathematical model of few statements, arrays, user defined functions of C-language. However, the present method may further be extended to any other high level language.

  1. Towards an Existential Types Model for Java with Wildcards

    DEFF Research Database (Denmark)

    Cameron, Nicholas; Drossopoulou, Sophia; Ernst, Erik

    2007-01-01

    Wildcards extend Java generics by softening the mismatch between subtype and parametric polymorphism. Although they are a key part of the Java 5.0 programming language, a type system including wildcards has never been proven type sound. Wildcards have previously been formalised as existential typ...

  2. Eye Typing using Markov and Active Appearance Models

    DEFF Research Database (Denmark)

    Hansen, Dan Witzner; Hansen, John Paulin; Nielsen, Mads

    2002-01-01

    We propose a non-intrusive eye tracking system intended for the use of everyday gaze typing using web cameras. We argue that high precision in gaze tracking is not needed for on-screen typing due to natural language redundancy. This facilitates the use of low-cost video components for advanced...

  3. Accurate modeling of vector hysteresis using a superposition of Preisach-type models

    Energy Technology Data Exchange (ETDEWEB)

    Adly, A.A. [Cairo Univ., Giza (Egypt). Electrical Power and Machines Dept.; Mayergoyz, I.D. [Univ. of Maryland, College Park, MD (United States). Electrical Engineering Dept.

    1997-09-01

    Vector hysteresis models are basically regarded as helpful tools that can be utilized in simulating and/or predicting multi-dimensional field-media interactions. Simulations of energy loss in power devices having unoriented magnetic cores, read/write recording processes as well as tape and disk erasure approaches are examples of such interactions that are currently of considerable interest. Vector hysteresis models are generally regarded as helpful tools that can be utilized in simulating multi-dimensional field-media interactions. In this paper, simulation of vector hysteresis is proposed by using a superposition of isotropic Preisach-type models. This approach gives the opportunity to fully incorporate rotational experimental results in its identification procedure, thus leading to higher simulation accuracy. Detailed solution of the model identification problem and some experimental testing results are given in the paper.

  4. Evaluation of anti-diabetic activity of Glucova Active Tablet on Type I and Type II diabetic model in rats

    Directory of Open Access Journals (Sweden)

    Hardik Soni

    2014-01-01

    Full Text Available Background: Glucova Active Tablet is a proprietary Ayurvedic formulation with ingredients reported for anti-hyperglycemic, anti-hyperlipidemic activity and antioxidant properties. Objective: Evaluation of anti-diabetic activity of Glucova Active Tablet on Type I and Type II diabetic model in rats. Materials and Methods: Experimental Type I diabetes was induced in 24 albino rats with intra-peritoneal injection of streptozotocin (50 mg/kg. Type II diabetes was induced in 18 albino rats by intra-peritoneal injection of streptozotocin (35 mg/kg along with high fat diet. The rats were divided in 5 groups for Type I model and 4 groups for Type II model. Normal control group was kept common for both experimental models. Glucova Active Tablet (108 mg/kg treatment was provided for 28 days twice daily orally. Fasting blood glucose level, serum lipid profile and liver anti-oxidant parameters like superoxide dismutase and reduced glutathione was carried out in both experimental models. Pancreas histopathology was also done. Statistical analysis were done by ′analysis of variance′ test followed by post hoc Tukey′s test, with significant level of P < 0.05.Results and Discussion: Glucova Active Tablet showed significant effect on fasting blood glucose level. It also showed significant alteration in lipid profile and antioxidant parameters. Histopathology study revealed restoration of beta cells in pancreas in Glucova Active Tablet treated group. Conclusion: Finding of this study concludes that Glucova Active Tablet has shown promising anti-diabetic activity in Type I and Type II diabetic rats. It was also found showing good anti-hyperlipidemic activity and anti-oxidant property.

  5. Evaluation of anti-diabetic activity of Glucova Active Tablet on Type I and Type II diabetic model in rats

    Science.gov (United States)

    Soni, Hardik; Patel, Sejal; Patel, Ghanshyam; Paranjape, Archana

    2014-01-01

    Background: Glucova Active Tablet is a proprietary Ayurvedic formulation with ingredients reported for anti-hyperglycemic, anti-hyperlipidemic activity and antioxidant properties. Objective: Evaluation of anti-diabetic activity of Glucova Active Tablet on Type I and Type II diabetic model in rats. Materials and Methods: Experimental Type I diabetes was induced in 24 albino rats with intra-peritoneal injection of streptozotocin (50 mg/kg). Type II diabetes was induced in 18 albino rats by intra-peritoneal injection of streptozotocin (35 mg/kg) along with high fat diet. The rats were divided in 5 groups for Type I model and 4 groups for Type II model. Normal control group was kept common for both experimental models. Glucova Active Tablet (108 mg/kg) treatment was provided for 28 days twice daily orally. Fasting blood glucose level, serum lipid profile and liver anti-oxidant parameters like superoxide dismutase and reduced glutathione was carried out in both experimental models. Pancreas histopathology was also done. Statistical analysis were done by ‘analysis of variance’ test followed by post hoc Tukey's test, with significant level of P < 0.05. Results and Discussion: Glucova Active Tablet showed significant effect on fasting blood glucose level. It also showed significant alteration in lipid profile and antioxidant parameters. Histopathology study revealed restoration of beta cells in pancreas in Glucova Active Tablet treated group. Conclusion: Finding of this study concludes that Glucova Active Tablet has shown promising anti-diabetic activity in Type I and Type II diabetic rats. It was also found showing good anti-hyperlipidemic activity and anti-oxidant property. PMID:24948860

  6. Advanced accident sequence precursor analysis level 1 models

    Energy Technology Data Exchange (ETDEWEB)

    Sattison, M.B.; Thatcher, T.A.; Knudsen, J.K.; Schroeder, J.A.; Siu, N.O. [Idaho National Engineering Lab., Idaho National Lab., Idaho Falls, ID (United States)

    1996-03-01

    INEL has been involved in the development of plant-specific Accident Sequence Precursor (ASP) models for the past two years. These models were developed for use with the SAPHIRE suite of PRA computer codes. They contained event tree/linked fault tree Level 1 risk models for the following initiating events: general transient, loss-of-offsite-power, steam generator tube rupture, small loss-of-coolant-accident, and anticipated transient without scram. Early in 1995 the ASP models were revised based on review comments from the NRC and an independent peer review. These models were released as Revision 1. The Office of Nuclear Regulatory Research has sponsored several projects at the INEL this fiscal year to further enhance the capabilities of the ASP models. Revision 2 models incorporates more detailed plant information into the models concerning plant response to station blackout conditions, information on battery life, and other unique features gleaned from an Office of Nuclear Reactor Regulation quick review of the Individual Plant Examination submittals. These models are currently being delivered to the NRC as they are completed. A related project is a feasibility study and model development of low power/shutdown (LP/SD) and external event extensions to the ASP models. This project will establish criteria for selection of LP/SD and external initiator operational events for analysis within the ASP program. Prototype models for each pertinent initiating event (loss of shutdown cooling, loss of inventory control, fire, flood, seismic, etc.) will be developed. A third project concerns development of enhancements to SAPHIRE. In relation to the ASP program, a new SAPHIRE module, GEM, was developed as a specific user interface for performing ASP evaluations. This module greatly simplifies the analysis process for determining the conditional core damage probability for a given combination of initiating events and equipment failures or degradations.

  7. A Dirac type xp-Model and the Riemann Zeros

    CERN Document Server

    Gupta, Kumar S; de Queiroz, Amilcar R

    2012-01-01

    We propose a Dirac like modification of the xp-model to a $x \\slashed{p}$ model on a semi-infinite cylinder. This model is inspired on recent work by Sierra et al. on the xp-model on the half-line. Our model realizes the Berry-Keating conjecture on the Riemann zeros. We indicate the connection of our model to that of gapped graphene with a supercritical Coulomb charge, which might provide a physical system for the study of the zeros of the Riemann Zeta function.

  8. The UEFA model in identification of types, severity and mechanism ...

    African Journals Online (AJOL)

    South African Journal of Sports Medicine ... To describe the types, severity, prevalence and mechanism of injuries ... The findings of this study will serve to guide the development and implementation of injury prevention strategies in the NPL.

  9. Two types of glitches in a solid quark star model

    OpenAIRE

    Lu, Jiguang; Zhou, Enping

    2015-01-01

    TThe glitch of anomalous X-ray pulsars \\& soft gamma repeaters (AXP/SGRs) usually accompanied with detectable energy releases manifesting as X-ray bursts or outbursts, while the glitch of some pulsars like Vela release negligible energy. We find that these two types of glitches can naturally correspond to two types of starquake of solid strange stars. By applying the EoS of quark cluster star and some realistic pulsar parameters, we can reproduce consistent results compared with previous cons...

  10. Critical frontier of the Potts and percolation models on triangular-type and kagome-type lattices. II. Numerical analysis.

    Science.gov (United States)

    Ding, Chengxiang; Fu, Zhe; Guo, Wenan; Wu, F Y

    2010-06-01

    In the preceding paper, one of us (F. Y. Wu) considered the Potts model and bond and site percolation on two general classes of two-dimensional lattices, the triangular-type and kagome-type lattices, and obtained closed-form expressions for the critical frontier with applications to various lattice models. For the triangular-type lattices Wu's result is exact, and for the kagome-type lattices Wu's expression is under a homogeneity assumption. The purpose of the present paper is twofold: First, an essential step in Wu's analysis is the derivation of lattice-dependent constants A,B,C for various lattice models, a process which can be tedious. We present here a derivation of these constants for subnet networks using a computer algorithm. Second, by means of a finite-size scaling analysis based on numerical transfer matrix calculations, we deduce critical properties and critical thresholds of various models and assess the accuracy of the homogeneity assumption. Specifically, we analyze the q -state Potts model and the bond percolation on the 3-12 and kagome-type subnet lattices (n×n):(n×n) , n≤4 , for which the exact solution is not known. Our numerical determination of critical properties such as conformal anomaly and magnetic correlation length verifies that the universality principle holds. To calibrate the accuracy of the finite-size procedure, we apply the same numerical analysis to models for which the exact critical frontiers are known. The comparison of numerical and exact results shows that our numerical values are correct within errors of our finite-size analysis, which correspond to 7 or 8 significant digits. This in turn infers that the homogeneity assumption determines critical frontiers with an accuracy of 5 decimal places or higher. Finally, we also obtained the exact percolation thresholds for site percolation on kagome-type subnet lattices (1×1):(n×n) for 1≤n≤6 .

  11. Impairment-Factor-Based Audiovisual Quality Model for IPTV: Influence of Video Resolution, Degradation Type, and Content Type

    Directory of Open Access Journals (Sweden)

    Garcia MN

    2011-01-01

    Full Text Available This paper presents an audiovisual quality model for IPTV services. The model estimates the audiovisual quality of standard and high definition video as perceived by the user. The model is developed for applications such as network planning and packet-layer quality monitoring. It mainly covers audio and video compression artifacts and impairments due to packet loss. The quality tests conducted for model development demonstrate a mutual influence of the perceived audio and video quality, and the predominance of the video quality for the overall audiovisual quality. The balance between audio quality and video quality, however, depends on the content, the video format, and the audio degradation type. The proposed model is based on impairment factors which quantify the quality-impact of the different degradations. The impairment factors are computed from parameters extracted from the bitstream or packet headers. For high definition video, the model predictions show a correlation with unknown subjective ratings of 95%. For comparison, we have developed a more classical audiovisual quality model which is based on the audio and video qualities and their interaction. Both quality- and impairment-factor-based models are further refined by taking the content-type into account. At last, the different model variants are compared with modeling approaches described in the literature.

  12. Comparison of Return Stroke Current Profiles for Transmission-Line-Type and Traveling-Current-Source-Type Models

    Directory of Open Access Journals (Sweden)

    J.O. Adepitan

    2012-05-01

    Full Text Available The study is aimed at determining the dependence of the current along a channel on the model used, assuming the same base current. We compared three transmission-line-type models, namely: Transmission Line (TL, Modified Transmission Line with Linear decay, Modified Transmission Line with Exponential decay and two traveling-current-source-type models: Bruce-Golde (BG and Traveling Current Source (TCS models. The current profiles along the channel at different heights predicted by these models are presented and discussed. Comparison is based on the assumption that all the models have the same base current. It was found that at low heights and within a time window frame of 15 :s, the currents of the transmission-line-type models predict a zero value at one time or the other with a maximum turning point following some 1:s after. A linear relationship is predicted between the current peak and the channel height. A discontinuity of current peak was observed at high heights. No zero value of current was recorded in case of TCS both at low and high channel heights.

  13. Bianchi VI cosmological models representing perfect fluid and radiation with electric-type free gravitational fields

    Science.gov (United States)

    Roy, S. R.; Banerjee, S. K.

    1992-11-01

    A homogeneous Bianchi type VIh cosmological model filled with perfect fluid, null electromagnetic field and streaming neutrinos is obtained for which the free gravitational field is of the electric type. The barotropic equation of statep = (γ-1)ɛ is imposed in the particular case of Bianchi VI0 string models. Various physical and kinematical properties of the models are discussed.

  14. Wegner estimate for discrete alloy-type models

    CERN Document Server

    Veselić, Ivan

    2010-01-01

    We study discrete alloy-type random Schr\\"odinger operators on $\\ell^2(\\mathbb{Z}^d)$. Wegner estimates are bounds on the average number of eigenvalues in an energy interval of finite box restrictions of these types of operators. If the single site potential is compactly supported and the distribution of the coupling constant is of bounded variation a Wegner estimate holds. The bound is polynomial in the volume of the box and thus applicable as an ingredient for a localisation proof via multiscale analysis.

  15. String coupling and interactions in type IIB matrix model

    CERN Document Server

    Kitazawa, Yoshihisa

    2008-01-01

    We investigate the interactions of closed strings in IIB matrix model. The basic interaction of the closed superstring is realized by the recombination of two intersecting strings. Such interaction is investigated in IIB matrix model via two dimensional noncommutative gauge theory in the IR limit. By estimating the probability of the recombination, we identify the string coupling g_s in IIB matrix model. We confirm that our identification is consistent with matrix string theory.

  16. Jeans type instability for a chemotactic model of cellular aggregation

    CERN Document Server

    Chavanis, Pierre-Henri

    2008-01-01

    We consider an inertial model of chemotactic aggregation generalizing the Keller-Segel model and we study the linear dynamical stability of an infinite and homogeneous distribution of cells (bacteria, amoebae, endothelial cells,...) when inertial effects are accounted for. These inertial terms model cells directional persistance. We determine the condition of instability and the growth rate of the perturbation as a function of the cell density and the wavelength of the perturbation. We discuss the differences between overdamped (Keller-Segel) and inertial models. Finally, we show the analogy between the instability criterion for biological populations and the Jeans instability criterion in astrophysics.

  17. Implementation of Electrical Simulation Model for IEC Standard Type-3A Generator

    DEFF Research Database (Denmark)

    Subramanian, Chandrasekaran; Casadei, Domenico; Tani, Angelo

    2013-01-01

    turbine with partial scale power converter WEG including a two mass mechanical model. The generic models for fixed and variable speed WEGs models are suitable for fundamental frequency positive sequence response simulations during short events in the power system such as voltage dips. The wind power......This paper describes the implementation of electrical simulation model for IEC 61400-27-1 standard Type-3A generator. A general overview of the different wind electric generators(WEG) types are given and the main focused on Type-3A WEG standard models, namely a model for a variable speed wind...

  18. Selecting Human Error Types for Cognitive Modelling and Simulation

    NARCIS (Netherlands)

    Mioch, T.; Osterloh, J.P.; Javaux, D.

    2010-01-01

    This paper presents a method that has enabled us to make a selection of error types and error production mechanisms relevant to the HUMAN European project, and discusses the reasons underlying those choices. We claim that this method has the advantage that it is very exhaustive in determining the re

  19. What uses are mating types? The "developmental switch" model.

    Science.gov (United States)

    Perrin, Nicolas

    2012-04-01

    Why mating types exist at all is subject to much debate. Among hypotheses, mating types evolved to control organelle transmission during sexual reproduction, or to prevent inbreeding or same-clone mating. Here I review data from a diversity of taxa (including ciliates, algae, slime molds, ascomycetes, and basidiomycetes) to show that the structure and function of mating types run counter the above hypotheses. I argue instead for a key role in triggering developmental switches. Genomes must fulfill a diversity of alternative programs along the sexual cycle. As a haploid gametophyte, an individual may grow vegetatively (through haploid mitoses), or initiate gametogenesis and mating. As a diploid sporophyte, similarly, it may grow vegetatively (through diploid mitoses) or initiate meiosis and sporulation. Only diploid sporophytes (and not haploid gametophytes) should switch on the meiotic program. Similarly, only haploid gametophytes (not sporophytes) should switch on gametogenesis and mating. And they should only do so when other gametophytes are ready to do the same in the neighborhood. As argued here, mating types have evolved primarily to switch on the right program at the right moment. © 2012 The Author(s). Evolution© 2012 The Society for the Study of Evolution.

  20. DESIGN OF THE RESEARCH INSTITUTION TYPE SITE MODEL

    Directory of Open Access Journals (Sweden)

    Natalia T. Zadorozhna

    2014-01-01

    Full Text Available The description of the model of site of research institution of NAPS of Ukraine (TSRI is presented. Goals and objectives оf the TSRI model are defined. Web 2.0 theoretical base for site development is considered, as well as described information environment, TSRI internet and intranet models. There are substantiated the site structure, design and site layout for research institution of NAPS of Ukraine. The example of the website of the Institute of Information Technologies and Learning Tools of the NAPS of Ukraine based on the TSRI model is showen. The technological aspects of the TSRI model are considered. There is given the scheme of internet-intranet environment to support scientific publications on pedagogical and psychological sciences. This paper is intended to web designers, researchers and administrative staff of research institutions.

  1. Forest type mapping using incorporation of spatial models and ETM+ data.

    Science.gov (United States)

    Joibary, Shaban Shataee; Darvishsefat, Ali A; Kellenberger, Tobias W

    2007-07-15

    Results of former researches have shown that spectrally based analysis alone could not satisfy forest type classification in mountainous mixed forests. Forest type based on composed different parameters such as topography elements like aspect, elevation and slop. These elements that are affected on occurrences of forest type can be stated as spatial distribution models. Using ancillary data integrated with spectral data could help to separate forest type. In order to find the abilities of using topographic spatial predictive models to improve forest type classification, an investigation was carried out to classify forest type using ETM+ data in a part of northern forests of Iran. The Tasseled Cap, Ratioing transformations and Principal Component Analysis were applied to the spectral bands. The best spectral and predictive data sets for classifying forest type using maximum likelihood classification were chosen using the Bhattacharya seperability index. Primary analysis between forest type and topographic parameters showed that elevation and aspect are most correlated with the occurrences of type. Probability occurrence rates of forest type were extracted in the aspect; elevation, integrated aspect and elevation as well as homogeneous units structured on elevation and aspect classes. Based on occurrence rates of forest type, spatial predictive distribution models were generated for each type individually. Classification of the best spectral data sets was accomplished by maximum likelihood classifier and using these spatial predictive models. Results were assessed using a sample ground truth of forest type. This study showed that spatial predictive models could considerably improve the results compared with spectral data alone from 49 to 60%. Among spatial models used, the spatial predictive models constructed based on the homogeneous units could improve results in comparison to other models. Applying other parameters related to forest type like soil maps would

  2. Mississippi Valley-Type Lead-Zinc Deposit Model

    Science.gov (United States)

    Leach, David L.; Taylor, Ryan D.

    2009-01-01

    Mississippi Valley-type (MVT) lead-zinc (Pb+Zn) deposits are found throughout the world, and these deposits are characteristically distributed over hundreds of square kilometers that define individual ore districts. The median size of individual MVT deposits is 7.0 million tonnes with grades of about 7.9 percent Pb+Zn metal. However, MVT deposits usually occur in extensive districts consisting of several to as many as 400 deposits. Nearly one-quarter of the world's sedimentary and volcanic rock-hosted Pb+Zn resources are found in these deposits, with by-product commodities including silver (Ag), copper (Cu), and indium (In) for some deposits. Environmentally, MVT deposits are less of a concern than other types of mineral deposits since the carbonate-host rocks mitigate many environmental concerns.

  3. Dynamical model for spindown of solar-type stars

    CERN Document Server

    Sood, Aditi; Hollerbach, Rainer

    2016-01-01

    Since their formation, stars slow down their rotation rates by the removal of angular momentum from their surfaces, e.g. via stellar winds. Despite the complexity of the processes involved, a traditional model, where the removal of angular momentum loss by magnetic fields is prescribed, has provided a useful framework to understand observational relations between stellar rotation and age and magnetic field strength. Here, a spindown model is proposed where loss of angular momentum by magnetic fields is evolved dynamically, instead of being kinematically prescribed. To this end, we evolve the stellar rotation and magnetic field simultaneously over stellar evolution time by extending our previous work on a dynamo model which incorporates the nonlinear feedback mechanisms on rotation and magnetic fields. Our extended model reproduces key observations and explains the presence of the two branches of (fast and slow rotating) stars which have different relations between rotation rate $\\Omega$ vs. time (age), magnet...

  4. Holonomy observables in Ponzano-Regge type state sum models

    CERN Document Server

    Barrett, John W

    2011-01-01

    We study observables on group elements in the Ponzano-Regge model. We show that these observables have a natural interpretation in terms of Feynman diagrams on a sphere and contrast them to the well studied observables on the spin labels. We elucidate this interpretation by showing how they arise from the no-gravity limit of the Turaev-Viro model and Chern-Simons theory.

  5. Helium in Double-Detonation Models of Type Ia Supernovae

    CERN Document Server

    Boyle, Aoife; Hachinger, Stephan; Kerzendorf, Wolfgang

    2016-01-01

    The double-detonation explosion model has been considered a candidate for explaining astrophysical transients with a wide range of luminosities. In this model, a carbon-oxygen white dwarf star explodes following detonation of a surface layer of helium. One potential signature of this explosion mechanism is the presence of unburned helium in the outer ejecta, left over from the surface helium layer. In this paper we present simple approximations to estimate the optical depths of important He I lines in the ejecta of double-detonation models. We use these approximations to compute synthetic spectra, including the He I lines, for double-detonation models obtained from hydrodynamical explosion simulations. Specifically, we focus on photospheric-phase predictions for the near-infrared 10830 \\AA~and 2 $\\mu$m lines of He I. We first consider a double detonation model with a luminosity corresponding roughly to normal SNe Ia. This model has a post-explosion unburned He mass of 0.03 $M_{\\odot}$ and our calculations sug...

  6. A dynamical systems approach to the tilted Bianchi models of solvable type

    Science.gov (United States)

    Coley, Alan; Hervik, Sigbjørn

    2005-02-01

    We use a dynamical systems approach to analyse the tilting spatially homogeneous Bianchi models of solvable type (e.g., types VIh and VIIh) with a perfect fluid and a linear barotropic γ-law equation of state. In particular, we study the late-time behaviour of tilted Bianchi models, with an emphasis on the existence of equilibrium points and their stability properties. We briefly discuss the tilting Bianchi type V models and the late-time asymptotic behaviour of irrotational Bianchi type VII0 models. We prove the important result that for non-inflationary Bianchi type VIIh models vacuum plane-wave solutions are the only future attracting equilibrium points in the Bianchi type VIIh invariant set. We then investigate the dynamics close to the plane-wave solutions in more detail, and discover some new features that arise in the dynamical behaviour of Bianchi cosmologies with the inclusion of tilt. We point out that in a tiny open set of parameter space in the type IV model (the loophole) there exist closed curves which act as attracting limit cycles. More interestingly, in the Bianchi type VIIh models there is a bifurcation in which a set of equilibrium points turns into closed orbits. There is a region in which both sets of closed curves coexist, and it appears that for the type VIIh models in this region the solution curves approach a compact surface which is topologically a torus.

  7. Bianchi Type-I cosmological mesonic stiff fluid models in Lyra's geometry

    Indian Academy of Sciences (India)

    S D Katore; S V Thakare; K S Adhao

    2008-07-01

    Bianchi Type-I cosmological models in Lyra's geometry are obtained when the source of gravitational field is a perfect fluid coupled with massless mesonic scalar field. Some physical and kinematical properties of the models are also discussed.

  8. Explicit chiral symmetry breaking in Gross-Neveu type models

    Energy Technology Data Exchange (ETDEWEB)

    Boehmer, Christian

    2011-07-25

    This thesis is devoted to the study of a 1+1-dimensional, fermionic quantum field theory with Lagrangian L= anti {psi}i{gamma}{sup {mu}}{partial_derivative}{sub {mu}}{psi}-m{sub 0} anti {psi}{psi}+(g{sup 2})/(2)(anti {psi}{psi}){sup 2}+(G{sup 2})/(2)(anti {psi}i{gamma}{sub 5}{psi}){sup 2} in the limit of an infinite number of flavors, using semiclassical methods. The main goal of the present work was to see what changes if we allow for explicit chiral symmetry breaking, either by a bare mass term, or a splitting of the scalar and pseudo-scalar coupling constants, or both. In the first case, this becomes the massive NJL{sub 2} model. In the 2nd and 3rd cases we are dealing with a model largely unexplored so far. The first half of this thesis deals with the massive NJL{sub 2} model. Before attacking the phase diagram, it was necessary to determine the baryons of the model. We have carried out full numerical Hartree-Fock calculations including the Dirac sea. The most important result is the first complete phase diagram of the massive NJL{sub 2} model in ({mu},T,{gamma}) space, where {gamma} arises from m{sub 0} through mass renormalization. In the 2nd half of the thesis we have studied a generalization of the massless NJL{sub 2} model with two different (scalar and pseudoscalar) coupling constants, first in the massless version. Renormalization of the 2 coupling constants leads to the usual dynamical mass by dynamical transmutation, but in addition to a novel {xi} parameter interpreted as chiral quenching parameter. As far as baryon structure is concerned, the most interesting result is the fact that the new baryons interpolate between the kink of the GN model and the massless baryon of the NJL{sub 2} model, always carrying fractional baryon number 1/2. The phase diagram of the massless model with 2 coupling constants has again been determined numerically. At zero temperature we have also investigated the massive, generalized GN model with 3 parameters. It is well

  9. TRNFLOW: Integration of the COMIS air current simulation model in the TRNSYS building model TYPE 56; TRNFLOW: Integration des Luftstroemungsmodels COMIS in das TRNSYS Gebaeudemodel TYPE 56

    Energy Technology Data Exchange (ETDEWEB)

    Welfonder, T.; Hiller, M.; Holst, S. [TRANSSOLAR Energietechnik GmbH, Stuttgart (Germany); Weber, A.; Koschenz, M. [EMPA, Abt. Energiesysteme/Haustechnik, Duebendorf (Switzerland)

    2003-07-01

    In the thermal building model TRNSYS Type 56 the air flows between the zones and from the outside are defined by the user as input values. In natural ventilation systems these values depend on external wind pressures and the inside and outside temperatures. To meet these requirements there has to be a link to an airflow model. For these purposes in TRNFLOW the multizone air flow model COMIS has been integrated into Type 56. An internal solver algorithm optimized for this task iterates between the two models in every time step until the results are consistent. The capabilities of the existing user interface PREBID were enlarged to allow input of the necessary data for the air flow model. Therewith a user-friendly handling of the linked models will be guaranteed. With TRNFLOW the building simulation with TRNSYS has moved a major step forward. (orig.)

  10. Fine-structure constant constraints on Bekenstein-type models

    CERN Document Server

    Leal, P M M; Ventura, L B

    2014-01-01

    Astrophysical tests of the stability of dimensionless fundamental couplings, such as the fine-structure constant $\\alpha$, are an area of much increased recent activity, following some indications of possible spacetime variations at the few parts per million level. Here we obtain updated constraints on the Bekenstein-Sandvik-Barrow-Magueijo model, which is arguably the simplest model allowing for $\\alpha$ variations. Recent accurate spectroscopic measurements allow us to improve previous constraints by about an order of magnitude. We briefly comment on the dependence of the results on the data sample, as well as on the improvements expected from future facilities.

  11. 75 FR 91 - Airworthiness Directives; Bombardier, Inc. (Type Certificate Previously Held by Canadair) Model...

    Science.gov (United States)

    2010-01-04

    ... Directives; Bombardier, Inc. (Type Certificate Previously Held by Canadair) Model CL-600-2B16 (CL-604...: Bombardier, Inc. (Type Certificate Previously Held by Canadair): Docket No. FAA-2009-1227; Directorate... (b) None. Applicability (c) This AD applies to Bombardier, Inc. (Type Certificate previously held...

  12. Lanchester-Type Models of Warfare. Volume II

    Science.gov (United States)

    1980-10-01

    verification of combat models are as follows: 594 (1) principle of uniformitarianism does not hold, (2) systems are only partially observable, (3...the principle of uniformitarianism , which holds that physical and biological process- es, conditions, and operations do not change over time (i.e. uni

  13. Robust model identification applied to type 1diabetes

    DEFF Research Database (Denmark)

    Finan, Daniel Aaron; Jørgensen, John Bagterp; Poulsen, Niels Kjølstad;

    2010-01-01

    In many realistic applications, process noise is known to be neither white nor normally distributed. When identifying models in these cases, it may be more effective to minimize a different penalty function than the standard sum of squared errors (as in a least-squares identification method...

  14. Bianchi Type-I, V and VIo models in modified generalized scalar–tensor theory

    Indian Academy of Sciences (India)

    T Singh; R Chaubey

    2007-08-01

    In modified generalized scalar–tensor (GST) theory, the cosmological term is a function of the scalar field and its derivatives $\\dot{}^{2}$. We obtain exact solutions of the field equations in Bianchi Type-I, V and VIo space–times. The evolution of the scale factor, the scalar field and the cosmological term has been discussed. The Bianchi Type-I model has been discussed in detail. Further, Bianchi Type-V and VIo models can be studied on the lines similar to Bianchi Type-I model.

  15. Desensitization and Modeling Treatments of Spider Fear Using Two Types of Scenes

    Science.gov (United States)

    Denney, Douglas R.; Sullivan, Bernard J.

    1976-01-01

    Three types of therapy were combined with two types of scenes. Spider-phobic subjects were assigned to one of the six treatment conditions or to an untreated control group. In general, (a) Desensitization and modeling therapies were equally effective; (b) modeling alone was more effective than mere exposure to the phobic object. (Author)

  16. Limits from Weak Gravity Conjecture on Chaplygin-Gas-Type Models

    Institute of Scientific and Technical Information of China (English)

    WU Xing; ZHU Zong-Hong

    2008-01-01

    @@ The weak gravity conjecture is proposed as a criterion to distinguish the landscape from the swampland in string theory. As an application in cosmology of this conjecture, we use it to impose theoretical constraint on parameters of the Chaplygin-gas-type models. Our analysis indicates that the Chaplygin-gas-type models realized in quintessence field are in the swampland.

  17. Comparison between one-dimensional and two-dimensional models for Josephson junctions of overlap type

    DEFF Research Database (Denmark)

    Eilbeck, J. C; Lomdahl, P.S.; Olsen, O.H.

    1985-01-01

    A two-dimensional model of Josephson junction of overlap type is presented. The energy input is provided through induced magnetic fields modeled by a set of boundary conditions. In the limit of a very narrow junction, this model reduces to the one-dimensional model. Further, an equation derived f...

  18. Bianchi Type-IX viscous fluid cosmological model in general relativity

    Indian Academy of Sciences (India)

    Raj Bali; Mahesh Kumar Yadav

    2005-02-01

    Bianchi Type-IX viscous fluid cosmological model is investigated. To get a deterministic model, we have assumed the condition = ( is a constant) between metric potentials and where is the coefficient of shear viscosity and the scalar of expansion in the model. The coefficient of bulk viscosity () is taken as constant. The physical and geometrical aspects of the model are also discussed.

  19. Classical and quantum cosmology of Born-Infeld type models

    CERN Document Server

    Kamenshchik, Alexander; Kwidzinski, Nick

    2016-01-01

    We discuss Born-Infeld type fields (tachyon fields) in classical and quantum cosmology. We first partly review and partly extend the discussion of the classical solutions and focus in particular on the occurrence of singularities. For quantization, we employ geometrodynamics. In the case of constant potential, we discuss both Wheeler-DeWitt quantization and reduced quantization. We are able to give various solutions and discuss their asymptotics. For the case of general potential, we transform the Wheeler-DeWitt equation to a form where it leads to a difference equation. Such a difference equation was previously found in the quantization of black holes. We give explicit results for the cases of constant potential and inverse square potential and point out special features possessed by solutions of the difference equation.

  20. Type Testing of Model 7200 Automatic TLD Reader.

    Science.gov (United States)

    Malek Mohammadi, M; Hosseini Pooya, S M

    2017-04-20

    The type testing of measuring devices is one of the most important parts of a quality management system in a personal dosimetry services program. In this study, based upon the International Electrotechnical Commission (IEC) 62387 criteria, a reader-testing program was performed for a home-made personal thermoluminescent dosimetry (TLD) reader. The stability of the reader, the effects of light exposure, temperature and fluctuations of primary power supply on TLD read-outs as the main parameters were investigated in this program. Moreover, this study assesses some important criteria of dosimetry system including the non-linearity of response, reusability, after effect and overload that may include significant contribution in the performance of a reader. The results showed that the TLD reader met all requirements of the IEC for the reader tests by a large margin. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  1. Classical and quantum cosmology of Born-Infeld type models

    Science.gov (United States)

    Kamenshchik, Alexander; Kiefer, Claus; Kwidzinski, Nick

    2016-04-01

    We discuss Born-Infeld type fields (tachyon fields) in classical and quantum cosmology. We first partly review and partly extend the discussion of the classical solutions and focus in particular on the occurrence of singularities. For quantization, we employ geometrodynamics. In the case of constant potential, we discuss both Wheeler-DeWitt quantization and reduced quantization. We are able to give various solutions and discuss their asymptotics. For the case of general potential, we transform the Wheeler-DeWitt equation to a form where it leads to a difference equation. Such a difference equation was previously found in the quantization of black holes. We give explicit results for the cases of constant potential and inverse squared potential and point out special features possessed by solutions of the difference equation.

  2. Compass & Vernier Type Models in Indo Archaeology: Engineering Heritage

    Science.gov (United States)

    Bhattacharya, Deepak

    2015-09-01

    Two extant, dated, verifiable archaeological members are adduced to have radial type compass features, having scope for fractionation of angles (θ operators) in a constant manner with lookout facilities. The Archaeological Survey of India celebrates their apex achievements in the domain of engineering/survey devices of erstwhile societies. Possible correlation has been drawn between the representatives of the elusive Gola yantra and the Vikhyana yantra (circular instrument & looking device) as referred in Indian history and culture. Dadhi nauti (curd level) has been explained for the first time. Now, all of these are accessible to everyone. This work is the first time report, which relates to historical archaeology of lower date c. 600 AD.

  3. Model Predictive Control of Buoy Type Wave Energy Converter

    DEFF Research Database (Denmark)

    Soltani, Mohsen N.; Sichani, Mahdi T.; Mirzaei, Mahmood

    2014-01-01

    The paper introduces the Wavestar wave energy converter and presents the implementation of model predictive controller that maximizes the power generation. The ocean wave power is extracted using a hydraulic electric generator which is connected to an oscillating buoy. The power generator...... is an additive device attached to the buoy which may include damping, stiffness or similar terms hence will affect the dynamic motion of the buoy. Therefore such a device can be seen as a closed-loop controller. The objective of the wave energy converter is to harvest as much energy from sea as possible....... This approach is then taken into account and an MPC controller is designed for a model wave energy converter and implemented on a numerical example. Further, the power outtake of this controller is compared to the optimal controller as an indicator of the performance of the designed controller....

  4. Using suggestion to model different types of automatic writing.

    Science.gov (United States)

    Walsh, E; Mehta, M A; Oakley, D A; Guilmette, D N; Gabay, A; Halligan, P W; Deeley, Q

    2014-05-01

    Our sense of self includes awareness of our thoughts and movements, and our control over them. This feeling can be altered or lost in neuropsychiatric disorders as well as in phenomena such as "automatic writing" whereby writing is attributed to an external source. Here, we employed suggestion in highly hypnotically suggestible participants to model various experiences of automatic writing during a sentence completion task. Results showed that the induction of hypnosis, without additional suggestion, was associated with a small but significant reduction of control, ownership, and awareness for writing. Targeted suggestions produced a double dissociation between thought and movement components of writing, for both feelings of control and ownership, and additionally, reduced awareness of writing. Overall, suggestion produced selective alterations in the control, ownership, and awareness of thought and motor components of writing, thus enabling key aspects of automatic writing, observed across different clinical and cultural settings, to be modelled.

  5. On asymptotics of t-type regression estimation in multiple linear model

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    We consider a robust estimator (t-type regression estimator) of multiple linear regression model by maximizing marginal likelihood of a scaled t-type error t-distribution.The marginal likelihood can also be applied to the de-correlated response when the withinsubject correlation can be consistently estimated from an initial estimate of the model based on the independent working assumption. This paper shows that such a t-type estimator is consistent.

  6. Nonlinear Dynamic Modeling of Langevin-Type Piezoelectric Transducers

    Directory of Open Access Journals (Sweden)

    Nicolás Peréz Alvarez

    2015-11-01

    Full Text Available Langevin transducers are employed in several applications, such as power ultrasound systems, naval hydrophones, and high-displacement actuators. Nonlinear effects can influence their performance, especially at high vibration amplitude levels. These nonlinear effects produce variations in the resonant frequency, harmonics of the excitation frequency, in addition to loss of symmetry in the frequency response and “frequency domain hysteresis”. In this context, this paper presents a simplified nonlinear dynamic model of power ultrasound transducers requiring only two parameters for simulating the most relevant nonlinear effects. One parameter reproduces the changes in the resonance frequency and the other introduces the dependence of the frequency response on the history of the system. The piezoelectric constitutive equations are extended by a linear dependence of the elastic constant on the mechanical displacement amplitude. For introducing the frequency hysteresis, the elastic constant is computed by combining the current value of the mechanical amplitude with the previous state amplitude. The model developed in this work is applied for predicting the dynamic responses of a 26 kHz ultrasonic transducer. The comparison of theoretical and experimental responses, obtained at several input voltages around the tuned frequency, shows a good agreement, indicating that the model can accurately describe the transducer nonlinear behavior.

  7. Model Predictive Control of Buoy Type Wave Energy Converter

    DEFF Research Database (Denmark)

    Soltani, Mohsen; Sichani, Mahdi Teimouri; Mirzaei, Mahmood

    2014-01-01

    The paper introduces the Wavestar wave energy converter and presents the implementation of model predictive controller that maximizes the power generation. The ocean wave power is extracted using a hydraulic electric generator which is connected to an oscillating buoy. The power generator is an a....... This approach is then taken into account and an MPC controller is designed for a model WEC and implemented on a numerical example. Further, the power outtake of this controller is compared to the optimal controller as an indicator of the performance of the designed controller.......The paper introduces the Wavestar wave energy converter and presents the implementation of model predictive controller that maximizes the power generation. The ocean wave power is extracted using a hydraulic electric generator which is connected to an oscillating buoy. The power generator...... is an additive device attached to the buoy which may include damping, stiffness or similar terms hence will affect the dynamic motion of the buoy. Therefore such a device can be seen as a closed-loop controller. The objective of the wave energy converter is to harvest as much energy from sea as possible...

  8. Model Based Analysis of Ethnic Differences in Type 2 Diabetes

    DEFF Research Database (Denmark)

    Møller, Jonas Bech

    The present thesis deals with different aspects of population pharmacokinetic /pharmacodynamic (PK/PD) modelling of the glucose homeostatic system. The thesis consist of a summary report and four scientific research papers. A description of the main topics covered in the thesis is given in the su......The present thesis deals with different aspects of population pharmacokinetic /pharmacodynamic (PK/PD) modelling of the glucose homeostatic system. The thesis consist of a summary report and four scientific research papers. A description of the main topics covered in the thesis is given...... of the glucose homeostatic system, which is a complex feedback system mainly involving mainly organs such as the liver and the pancreas, the hormones insulin and glucagon, and the carbohydrate glucose. As for any other dynamical system, a proper characterisation at non-steady state, requires a proper input...... to the system. This input must reflect the circumstances in which one wants to draw conclusions. In this thesis the intake of oral glucose, which closely resembles the intake of food under daily living has been applied. Mathematical modelling of such complex physiologal phenomenas as the glucosehomeostatic...

  9. OPTICAL MODEL AND NUMERICAL SIMULATION OF THE NEW OFFSET TYPE PARABOLIC CONCENTRATOR WITH TWO TYPES OF SOLAR RECEIVERS

    Directory of Open Access Journals (Sweden)

    Saša Pavlović

    2015-08-01

    Full Text Available The paper presents a physical and mathematical model of the new offset type parabolic concentrator and a numerical procedure for predicting its optical performances. Also presented is the process of design and optical ray tracing analysis of a low cost solar concentrator for medium temperature applications. This study develops and applies a new mathematical model for estimating the intercept factor of the solar concentrator based on its geometrical and optical behavior. The solar concentrating system consists of three offset parabolic dish reflectors and a solar thermal absorber at the focus. Two types of absorbers are discussed. One is a flat plate circular absorber and the other a spiral smooth pipe absorber. The simulation results could serve as a useful reference for design and optimization of offset parabolic concentrators.

  10. Influence of Monomer Types on the Designability of a Protein-Model Chain

    Institute of Scientific and Technical Information of China (English)

    梁好均; 王元元

    2002-01-01

    In a three-dimensional off-lattice model, the method of Shakhnovich and Gutin for minimizing the Hamiltonian is applied to the design of a protein-model chain. The effect of the number of hydrophobic and hydrophilic monomer types on the designability ora protein-model chain is investigated. The simulation results reveal that the number of hydrophobic monomer types is a much more important factor than that of the polar monomer types in the design of a protein-model chain.

  11. Implementation of IEC Generic Model Type 1 Wind Turbine Generators using RTDS

    DEFF Research Database (Denmark)

    Cha, Seung-Tae; Wu, Qiuwei; Zhao, Haoran

    are useful tools to evaluate the impact of the wind power on the power system stability. Thus, a strong stimulus exists for the development of a generic dynamic model in order to further investigate the dynamic response of WTG under grid disturbances. This paper presents the implementation of the IEC generic...... Type 1A and 1B WTG models in the real time digital simulator (RTDS) environment. Case studies have been carried out to verify the performance of the IEC generic Type 1 WTG model under both steady state and dynamic conditions. The case study results show that the IEC generic Type 1 WTG model can...

  12. Velocity potential formulations of highly accurate Boussinesq-type models

    DEFF Research Database (Denmark)

    Bingham, Harry B.; Madsen, Per A.; Fuhrman, David R.

    2009-01-01

    processes on the weather side of reflective structures. Coast. Eng. 53, 929-945). An exact infinite series solution for the potential is obtained via a Taylor expansion about an arbitrary vertical position z=(z) over cap. For practical implementation however, the solution is expanded based on a slow...... variation of (z) over cap and terms are retained to first-order. With shoaling enhancement, the new models obtain a comparable accuracy in linear shoaling to the original velocity formulation. General consistency relations are also derived which are convenient for verifying that the differential operators...

  13. Aerodynamics on a transport aircraft type wing-body model

    Science.gov (United States)

    Schmitt, V.

    1982-01-01

    The DFLR-F4 wing-body combination is studied. The 1/38 model is formed by a 9.5 aspect ratio transonic wing and an Airbus A 310 fuselage. The F4 wing geometrical characteristics are described and the main experimental results obtained in the S2MA wind tunnel are discussed. Both wing-fuselage interferences and viscous effects, which are important on the wing due to a high rear loading, are investigated by performing 3D calculations. An attempt is made to find their limitations.

  14. Efficient Beam-Type Structural Modeling of Rotor Blades

    DEFF Research Database (Denmark)

    Couturier, Philippe; Krenk, Steen

    2015-01-01

    The present paper presents two recently developed numerical formulations which enable accurate representation of the static and dynamic behaviour of wind turbine rotor blades using little modeling and computational effort. The first development consists of an intuitive method to extract fully...... coupled six by six cross-section stiffness matrices with limited meshing effort. Secondly, an equilibrium based beam element accepting directly the stiffness matrices and accounting for large variations in geometry and material along the blade is presented. The novel design tools are illustrated...

  15. Complex Dynamics of an Adnascent-Type Game Model

    Directory of Open Access Journals (Sweden)

    Baogui Xin

    2008-01-01

    Full Text Available The paper presents a nonlinear discrete game model for two oligopolistic firms whose products are adnascent. (In biology, the term adnascent has only one sense, “growing to or on something else,” e.g., “moss is an adnascent plant.” See Webster's Revised Unabridged Dictionary published in 1913 by C. & G. Merriam Co., edited by Noah Porter. The bifurcation of its Nash equilibrium is analyzed with Schwarzian derivative and normal form theory. Its complex dynamics is demonstrated by means of the largest Lyapunov exponents, fractal dimensions, bifurcation diagrams, and phase portraits. At last, bifurcation and chaos anticontrol of this system are studied.

  16. Lensed Type Ia Supernovae as Probes of Cluster Mass Models

    CERN Document Server

    Nordin, J; Richard, J; Rykoff, E; Aldering, G; Amanullah, R; Atek, H; Barbary, K; Deustua, S; Fakhouri, H K; Fruchter, A S; Goobar, A; Hook, I; Hsiao, E Y; Huang, X; Kneib, J -P; Lidman, C; Meyers, J; Perlmutter, S; Saunders, C; Spadafora, A L; Suzuki, N

    2013-01-01

    Using three magnified Type Ia supernovae (SNe Ia) detected behind massive CLASH clusters (Abell~383, MACSJ1532 and MACSJ1720) observed using the Hubble Space Telescope (HST), we perform a first pilot study to see whether standardizable candles can be used to calibrate cluster mass maps created from strong lensing observations. Such calibrations will be crucial when next generation HST cluster surveys (e.g. FRONTIER) provide magnification maps that will, in turn, form the basis for the exploration of the high redshift universe. We demonstrate that supernovae can be used as "test beams" for this purpose. We use a combination of spectroscopic and photometric methods to classify the SNe and then determine the SN amplification factors using the SALT2/Union2.1 framework. We find SNe with significant amplification, up to a factor of 1.7 at $\\sim5\\sigma$ significance for SN-L2 behind MACSJ1720. We initially conducted this as a blind study to avoid fine tuning of parameters, and there we found a mean amplification dif...

  17. Spin-Up/Spin-Down models for Type Ia Supernovae

    CERN Document Server

    Di Stefano, R; Claeys, J S W

    2011-01-01

    In the single degenerate scenario for Type Ia supernova (SNeIa), a white dwarf (WD) must gain a significant amount of matter from a companion star. Because the accreted mass carries angular momentum, the WD is likely to achieve fast spin periods, which can increase the critical mass, $M_{crit}$, needed for explosion. When $M_{crit}$ is higher than the maximum mass achieved by the WD, the WD must spin down before it can explode. This introduces a delay between the time at which the WD has completed its epoch of mass gain and the time of the explosion. Matter ejected from the binary during mass transfer therefore has a chance to become diffuse, and the explosion occurs in a medium with a density similar to that of typical regions of the interstellar medium. Also, either by the end of the WD's mass increase or else by the time of explosion, the donor may exhaust its stellar envelope and become a WD. This alters, generally diminishing, explosion signatures related to the donor star. Nevertheless, the spin-up/spin...

  18. Implementation and Validation of IEC Generic Type 1A Wind Turbine Generator Model

    DEFF Research Database (Denmark)

    Zhao, Haoran; Wu, Qiuwei; Margaris, Ioannis

    2015-01-01

    This paper presents the implementation of the International Electrotechnical Commission (IEC) generic Type 1A wind turbine generator (WTG) model in Power Factory (PF) and the validation of the implemented model against field measurements. The IEC generic Type 1A WTG model structure is briefly...... described. The details are explained regarding how the two mass mechanical model is implemented when the generator mass is included in the PF built-in generator model. In order to verify the IEC generic Type 1A WTG model, the model to field measurement validation method was employed. The model to field...... the simulation results and measurements were calculated according to the voltage dip windows and the index definition specified in the IEC 61400-27-1 committee draft. Copyright © 2014 John Wiley & Sons, Ltd....

  19. Function Interface Models for Hardware Compilation: Types, Signatures, Protocols

    CERN Document Server

    Ghica, Dan R

    2009-01-01

    The problem of synthesis of gate-level descriptions of digital circuits from behavioural specifications written in higher-level programming languages (hardware compilation) has been studied for a long time yet a definitive solution has not been forthcoming. The argument of this essay is mainly methodological, bringing a perspective that is informed by recent developments in programming-language theory. We argue that one of the major obstacles in the way of hardware compilation becoming a useful and mature technology is the lack of a well defined function interface model, i.e. a canonical way in which functions communicate with arguments. We discuss the consequences of this problem and propose a solution based on new developments in programming language theory. We conclude by presenting a prototype implementation and some examples illustrating our principles.

  20. Projection-type estimation for varying coefficient regression models

    CERN Document Server

    Lee, Young K; Park, Byeong U; 10.3150/10-BEJ331

    2012-01-01

    In this paper we introduce new estimators of the coefficient functions in the varying coefficient regression model. The proposed estimators are obtained by projecting the vector of the full-dimensional kernel-weighted local polynomial estimators of the coefficient functions onto a Hilbert space with a suitable norm. We provide a backfitting algorithm to compute the estimators. We show that the algorithm converges at a geometric rate under weak conditions. We derive the asymptotic distributions of the estimators and show that the estimators have the oracle properties. This is done for the general order of local polynomial fitting and for the estimation of the derivatives of the coefficient functions, as well as the coefficient functions themselves. The estimators turn out to have several theoretical and numerical advantages over the marginal integration estimators studied by Yang, Park, Xue and H\\"{a}rdle [J. Amer. Statist. Assoc. 101 (2006) 1212--1227].

  1. Global instability in a Sellers-type model

    CERN Document Server

    Bodai, Tamas; Lunkeit, Frank; Boschi, Robert

    2014-01-01

    The Ghil-Sellers energy balance model of Earth's climate, features -- for a considerable range of the solar intensity -- two stable climate states (a warm and a cold snowball Earth), where the bistability results from the celebrated ice-albedo feedback. The unstable solution is obtained and characterized in this paper. We find such unstable states by applying for the first time in a geophysical context the so-called edge tracking method that has been used for studying multiple coexisting states in shear flows. We examine robustness, efficiency, and accuracy properties of the edge tracking algorithm. We find that the procedure is the most efficient when taking a single bisection per cycle. Due to the strong diffusivity of the system trajectories of transient dynamics, initialized between the stable states with respect to the mean temperature, are confined to the heteroclininc trajectory, one which connects the fixed unstable and stable states, after relatively short transient times. This constraint dictates a ...

  2. Improved ultrasonic differentiation model for structural coal types based on neural network

    Institute of Scientific and Technical Information of China (English)

    TIAN Zi-jian; WANG Fu-zhong; LI Tao; BAI Shan-shan

    2009-01-01

    In order to solve the difficulty of detailed recognition of subdivisions of structural coal types, a differentiation model that combines BP neural network with an ultrasonic reflection method is proposed. Structural coal types are recognized based on a suit-able consideration of ultrasonic speed, an ultrasonic attenuation coefficient, characteristics of ultrasonic transmission and other parameters relating to structural coal types. We have focused on a computational model of ultrasonic speed, attenuation coefficient in coal and differentiation algorithm of structural coal types based on a BP neural network. Experiments demonstrate that the model can distinguish structural coal types effectively. It is important for the improved ultrasonic differentiation model to predict coal and gas outbursts.

  3. Mathematical Model and Geometrical Model of Double Pitch ZN-type Worm Gear Set Based on Generation Mechanism

    Institute of Scientific and Technical Information of China (English)

    SHU Linsen; CAO Huajun; LI Xianchong; ZHANG Chenglong; LI Yuxia

    2015-01-01

    The current researches on the tooth surface mathematical equations and the theory of gearing malnly pay attention to the ordinary type worm gear set (e.g., ZN, ZA, or ZK). The research of forming mechanism and three-dimensional modeling method for the double pitch worm gear set is not enough. So there are some difficulties in mathematical model deducing and geometry modeling of double pitch ZN-type worm gear set based on generation mechanism. In order to establish the mathematical model and the precise geometric model of double pitch ZN-type worm gear set, the structural characteristics and generation mechanism of the double pitch ZN-type worm gear set are investigated. Mathematical model of the ZN-type worm gear set is derived based on its generation mechanism and the theory of gearing. According to the mathematical model of the worm gear set which has been developed, a geometry modeling method of the double pitch ZN-type worm and worm gear is presented. Furthermore, a geometrical precision calculate method is proposed to evaluate the geometrical quality of the double pitch worm gear set. As a result, the maximum error is less than 6´10–4 mm in magnitude, thus the model of the double pitch ZN-type worm gear set is avallable to meet the requirements of finite element analysis and engineering application. The derived mathematical model and the proposed geometrical modeling method are helpful to guiding the design, manufacture and contact analysis of the worm gear set.

  4. A macroscopic crowd motion model of gradient flow type

    CERN Document Server

    Maury, Bertrand; Santambrogio, Filippo

    2010-01-01

    A simple model to handle the flow of people in emergency evacuation situations is considered: at every point x, the velocity U(x) that individuals at x would like to realize is given. Yet, the incompressibility constraint prevents this velocity field to be realized and the actual velocity is the projection of the desired one onto the set of admissible velocities. Instead of looking at a microscopic setting (where individuals are represented by rigid discs), here the macroscopic approach is investigated, where the unknwon is the evolution of the density . If a gradient structure is given, say U is the opposite of the gradient of D where D is, for instance, the distance to the exit door, the problem is presented as a Gradient Flow in the Wasserstein space of probability measures. The functional which gives the Gradient Flow is neither finitely valued (since it takes into account the constraints on the density), nor geodesically convex, which requires for an ad-hoc study of the convergence of a discrete scheme.

  5. Matérn's hard core models of types I and II with arbitrary compact grains

    DEFF Research Database (Denmark)

    Kiderlen, Markus; Hörig, Mario

    Matérn's classical hard core models can be interpreted as models obtained from a stationary marked Poisson process by dependent thinning. The marks are balls of fixed radius, and a point is retained when its associated ball does not hit any other balls (type I) or when its random birth time is st...... of this model with the process of intact grains of the dead leaves model and the Stienen model leads to analogous results for the latter....

  6. Bianchi Type-I bulk viscous fluid string dust magnetized cosmological model in general relativity

    Indian Academy of Sciences (India)

    Raj Bali; Anjali

    2004-09-01

    Bianchi Type-I magnetized bulk viscous fluid string dust cosmological model is investigated. To get a determinate model, we have assumed the conditions and = constant where is the shear, the expansion in the model and the coefficient of bulk viscosity. The behaviour of the model in the presence and absence of magnetic field together with physical and geometrical aspects of the model are also discussed.

  7. Algebraic Specifications, Higher-order Types and Set-theoretic Models

    DEFF Research Database (Denmark)

    Kirchner, Hélène; Mosses, Peter David

    2001-01-01

    In most algebraic  specification frameworks, the type system is restricted to sorts, subsorts, and first-order function types. This is in marked contrast to the so-called model-oriented frameworks, which provide higer-order types, interpreted set-theoretically as Cartesian products, function spaces......, and power-sets. This paper presents a simple framework for algebraic specifications with higher-order types and set-theoretic models. It may be regarded as the basis for a Horn-clause approximation to the Z framework, and has the advantage of being amenable to prototyping and automated reasoning. Standard...

  8. Mathematically modelling the effects of pacing, finger strategies and urgency on numerical typing performance with queuing network model human processor.

    Science.gov (United States)

    Lin, Cheng-Jhe; Wu, Changxu

    2012-01-01

    Numerical typing is an important perceptual-motor task whose performance may vary with different pacing, finger strategies and urgency of situations. Queuing network-model human processor (QN-MHP), a computational architecture, allows performance of perceptual-motor tasks to be modelled mathematically. The current study enhanced QN-MHP with a top-down control mechanism, a close-loop movement control and a finger-related motor control mechanism to account for task interference, endpoint reduction, and force deficit, respectively. The model also incorporated neuromotor noise theory to quantify endpoint variability in typing. The model predictions of typing speed and accuracy were validated with Lin and Wu's (2011) experimental results. The resultant root-mean-squared errors were 3.68% with a correlation of 95.55% for response time, and 35.10% with a correlation of 96.52% for typing accuracy. The model can be applied to provide optimal speech rates for voice synthesis and keyboard designs in different numerical typing situations. An enhanced QN-MHP model was proposed in the study to mathematically account for the effects of pacing, finger strategies and internalised urgency on numerical typing performance. The model can be used to provide optimal pacing for voice synthesise systems and suggested optimal numerical keyboard designs under urgency.

  9. Tilted Bianchi type I dust fluid cosmological model in general relativity

    Indian Academy of Sciences (India)

    Raj Bali; Keshav Sharma

    2002-03-01

    In this paper, we have investigated a tilted Bianchi type I cosmological model filled with dust of perfect fluid in general relativity. To get a determinate solution, we have assumed a condition = between metric potentials. The physical and geometrical aspects of the model together with singularity in the model are also discussed.

  10. RBF-Type Artificial Neural Network Model Applied in Alloy Design of Steels

    Institute of Scientific and Technical Information of China (English)

    YOU Wei; LIU Ya-xiu; BAI Bing-zhe; FANG Hong-sheng

    2008-01-01

    RBF model, a new type of artificial neural network model was developed to design the content of carbon in low-alloy engineering steels. The errors of the ANN model are. MSE 0. 052 1, MSRE 17. 85%, and VOF 1. 932 9. The results obtained are satisfactory. The method is a powerful aid for designing new steels.

  11. A Linear Programming Model to Optimize Various Objective Functions of a Foundation Type State Support Program.

    Science.gov (United States)

    Matzke, Orville R.

    The purpose of this study was to formulate a linear programming model to simulate a foundation type support program and to apply this model to a state support program for the public elementary and secondary school districts in the State of Iowa. The model was successful in producing optimal solutions to five objective functions proposed for…

  12. Development and application of an oral challenge mouse model for studying Clostridium perfringens type D infection.

    Science.gov (United States)

    Fernandez-Miyakawa, Mariano E; Sayeed, Sameera; Fisher, Derek J; Poon, Rachael; Adams, Vicki; Rood, Julian I; McClane, Bruce A; Saputo, Julian; Uzal, Francisco A

    2007-09-01

    Clostridium perfringens type D isolates cause enterotoxemia in sheep, goats, and probably cattle. While the major disease signs and lesions of type D animal disease are usually attributed to epsilon toxin, a class B select agent, these bacteria typically produce several lethal toxins. Understanding of disease pathogenesis and development of improved vaccines are hindered by the lack of a small-animal model mimicking natural disease caused by type D isolates. Addressing this need, we developed an oral challenge mouse model of C. perfringens type D enterotoxemia. When BALB/c mice with a sealed anus were inoculated by intragastric gavage with type D isolates, 7 of 10 type D isolates were lethal, as defined by spontaneous death or severe clinical signs necessitating euthanasia. The lethalities of the seven type D isolates varied between 14 and 100%. Clinical signs in the lethally challenged mice included seizures, convulsions, hyperexcitability, and/or depression. Mild intestinal gas distention and brain edema were observed at necropsy in a few mice, while histology showed multifocal acute tubular necrosis of the kidney and edema in the lungs of most challenged mice that developed a clinical response. When the lethality of type D isolates in this model was compared with in vitro toxin production, only a limited correlation was observed. However, mice could be protected against lethality by intravenous passive immunization with an epsilon toxin antibody prior to oral challenge. This study provides an economical new model for studying the pathogenesis of C. perfringens type D infections.

  13. Development and Application of an Oral Challenge Mouse Model for Studying Clostridium perfringens Type D Infection▿

    Science.gov (United States)

    Fernandez-Miyakawa, Mariano E.; Sayeed, Sameera; Fisher, Derek J.; Poon, Rachael; Adams, Vicki; Rood, Julian I.; McClane, Bruce A.; Saputo, Julian; Uzal, Francisco A.

    2007-01-01

    Clostridium perfringens type D isolates cause enterotoxemia in sheep, goats, and probably cattle. While the major disease signs and lesions of type D animal disease are usually attributed to epsilon toxin, a class B select agent, these bacteria typically produce several lethal toxins. Understanding of disease pathogenesis and development of improved vaccines are hindered by the lack of a small-animal model mimicking natural disease caused by type D isolates. Addressing this need, we developed an oral challenge mouse model of C. perfringens type D enterotoxemia. When BALB/c mice with a sealed anus were inoculated by intragastric gavage with type D isolates, 7 of 10 type D isolates were lethal, as defined by spontaneous death or severe clinical signs necessitating euthanasia. The lethalities of the seven type D isolates varied between 14 and 100%. Clinical signs in the lethally challenged mice included seizures, convulsions, hyperexcitability, and/or depression. Mild intestinal gas distention and brain edema were observed at necropsy in a few mice, while histology showed multifocal acute tubular necrosis of the kidney and edema in the lungs of most challenged mice that developed a clinical response. When the lethality of type D isolates in this model was compared with in vitro toxin production, only a limited correlation was observed. However, mice could be protected against lethality by intravenous passive immunization with an epsilon toxin antibody prior to oral challenge. This study provides an economical new model for studying the pathogenesis of C. perfringens type D infections. PMID:17562765

  14. Study of models of the sine-Gordon type in flat and curved spacetime

    Energy Technology Data Exchange (ETDEWEB)

    Bazeia, D. [Universidade de Sao Paulo, Instituto de Fisica, Sao Paulo, SP (Brazil); Universidade Federal da Paraiba, Departamento de Fisica, Joao Pessoa, PB (Brazil); Universidade Federal de Campina Grande, Departamento de Fisica, Campina Grande, PB (Brazil); Losano, L. [Universidade Federal da Paraiba, Departamento de Fisica, Joao Pessoa, PB (Brazil); Universidade Federal de Campina Grande, Departamento de Fisica, Campina Grande, PB (Brazil); Menezes, R. [Universidade Federal de Campina Grande, Departamento de Fisica, Campina Grande, PB (Brazil); Rocha, Roldao da [Universidade Federal do ABC, Centro de Matematica, Computacao e Cognicao, Santo Andre, SP (Brazil)

    2013-07-15

    We study a new family of models of the sine-Gordon type, starting from the sine-Gordon model, including the double sine-Gordon, the triple one, and so on. The models appears as deformations of the starting model, with the deformation controlled by two parameters, one very small, used to control a linear expansion on it, and the other, which specifies the particular model in the family of models. We investigate the presence of topological defects, showing how the solutions can be constructed explicitly from the topological defects of the sine-Gordon model itself. In particular, we delve into the double sine-Gordon model in a braneworld scenario with a single extra dimension of infinite extent, showing that a stable gravity scenario is admissible. Also, we briefly show that the deformation procedure can be used iteratively, leading to a diversity of possibilities to construct families of models of the sine-Gordon type. (orig.)

  15. Modelling the economics of type 2 diabetes mellitus prevention: a literature review of methods.

    Science.gov (United States)

    Watson, P; Preston, L; Squires, H; Chilcott, J; Brennan, A

    2014-06-01

    Our objective was to review modelling methods for type 2 diabetes mellitus prevention cost-effectiveness studies. The review was conducted to inform the design of a policy analysis model capable of assisting resource allocation decisions across a spectrum of prevention strategies. We identified recent systematic reviews of economic evaluations in diabetes prevention and management of obesity. We extracted studies from two existing systematic reviews of economic evaluations for the prevention of diabetes. We extracted studies evaluating interventions in a non-diabetic population with type 2 diabetes as a modelled outcome, from two systematic reviews of obesity intervention economic evaluations. Databases were searched for studies published between 2008 and 2013. For each study, we reviewed details of the model type, structure, and methods for predicting diabetes and cardiovascular disease. Our review identified 46 articles and found variation in modelling approaches for cost-effectiveness evaluations for the prevention of type 2 diabetes. Investigation of the variables used to estimate the risk of type 2 diabetes suggested that impaired glucose regulation, and body mass index were used as the primary risk factors for type 2 diabetes. A minority of cost-effectiveness models for diabetes prevention accounted for the multivariate impacts of interventions on risk factors for type 2 diabetes. Twenty-eight cost-effectiveness models included cardiovascular events in addition to type 2 diabetes. Few cost-effectiveness models have flexibility to evaluate different intervention types. We conclude that to compare a range of prevention interventions it is necessary to incorporate multiple risk factors for diabetes, diabetes-related complications and obesity-related co-morbidity outcomes.

  16. Discriminating neutrino mass models using Type-II see-saw formula

    Indian Academy of Sciences (India)

    N Nimal Singh; Mahadev Patagiri; Mrinal Kumar Das

    2006-02-01

    An attempt has been made to discriminate theoretically the three possible patterns of neutrino mass models,viz., degenerate, inverted hierarchical and normal hierachical models, within the framework of Type-II see-saw formula. From detailed numerical analysis we are able to arrive at a conclusion that the inverted hierarchical model with the same CP phase (referred to as Type [IIA]), appears to be most favourable to survive in nature (and hence most stable), with the normal hierarchical model (Type [III]) and inverted hierarchical model with opposite CP phase (Type [IIB]), follow next. The degenerate models (Types [IA,IB,IC]) are found to be most unstable. The neutrino mass matrices which are obtained using the usual canonical see-saw formula (Type I), and which also give almost good predictions of neutrino masses and mixings consistent with the latest neutrino oscillation data, are re-examined in the presence of the left-handed Higgs triplet within the framework of non-canonical see-saw formula (Type II). We then estimate a parameter (the so-called discriminator) which may represent the minimum degree of suppression of the extra term arising from the presence of left-handed Higgs triplet, so as to restore the good predictions on neutrino masses and mixings already acquired in Type-I see-saw model. The neutrino mass model is said to be favourable and hence stable when its canonical see-saw term dominates over the non-canonical (perturbative) term, and this condition is used here as a criterion for discriminating neutrino mass models.

  17. Modeling of type-2 fuzzy cubic B-spline surface for flood data problem in Malaysia

    Science.gov (United States)

    Bidin, Mohd Syafiq; Wahab, Abd. Fatah

    2017-08-01

    Malaysia possesses a low and sloping land areas which may cause flood. The flood phenomenon can be analyzed if the surface data of the study area can be modeled by geometric modeling. Type-2 fuzzy data for the flood data is defined using type-2 fuzzy set theory in order to solve the uncertainty of complex data. Then, cubic B-spline surface function is used to produce a smooth surface. Three main processes are carried out to find a solution to crisp type-2 fuzzy data which is fuzzification (α-cut operation), type-reduction and defuzzification. Upon conducting these processes, Type-2 Fuzzy Cubic B-Spline Surface Model is applied to visualize the surface data of the flood areas that are complex uncertainty.

  18. Evidence Feed Forward Hidden Markov Model: A New Type Of Hidden Markov Model

    Directory of Open Access Journals (Sweden)

    Michael Del Rose

    2011-01-01

    Full Text Available The ability to predict the intentions of people based solely on their visual actions is a skill only performed by humans and animals. The intelligence of current computer algorithms has not reached this level of complexity, but there are several research efforts that are working towards it. With the number of classification algorithms available, it is hard to determine which algorithm works best for a particular situation. In classification of visual human intent data, Hidden Markov Models (HMM, and their variants, are leading candidates. The inability of HMMs to provide a probability in the observation to observation linkages is a big downfall in this classification technique. If a person is visually identifying an action of another person, they monitor patterns in the observations. By estimating the next observation, people have the ability to summarize the actions, and thus determine, with pretty good accuracy, the intention of the person performing the action. These visual cues and linkages are important in creating intelligent algorithms for determining human actions based on visual observations. The Evidence Feed Forward Hidden Markov Model is a newly developed algorithm which provides observation to observation linkages. The following research addresses the theory behind Evidence Feed Forward HMMs, provides mathematical proofs of their learning of these parameters to optimize the likelihood of observations with a Evidence Feed Forwards HMM, which is important in all computational intelligence algorithm, and gives comparative examples with standard HMMs in classification of both visual action data and measurement data; thus providing a strong base for Evidence Feed Forward HMMs in classification of many types of problems.

  19. Typelets - a rule-based evaluation model for dynamic, statically typed user interfaces

    DEFF Research Database (Denmark)

    Elsman, Martin; Schack-Nielsen, Anders

    2014-01-01

    -inference in MLFi, the features allow for type-level programming of user interfaces. The dynamic behavior of typelets are specified using declarative rules. The technique extends the flat spreadsheet programming model with higher-order rule composition techniques, extensive reuse, and type safety. A layout...

  20. ABO/Rh Blood-Typing Model: A Problem-Solving Activity

    Science.gov (United States)

    Wake, Carol

    2005-01-01

    An ARO/Rh Blood-Typing kit useful for students to visualize blood-typing activities and practice problem-solving skills with transfusion reactions is presented. The model also enables students to identify relationships between A, B, and Rh antigens and antibodies in blood and to understand molecular mechanisms involved in transfusion agglutination…

  1. ABO/Rh Blood-Typing Model: A Problem-Solving Activity

    Science.gov (United States)

    Wake, Carol

    2005-01-01

    An ARO/Rh Blood-Typing kit useful for students to visualize blood-typing activities and practice problem-solving skills with transfusion reactions is presented. The model also enables students to identify relationships between A, B, and Rh antigens and antibodies in blood and to understand molecular mechanisms involved in transfusion agglutination…

  2. Analysis and synthesis for interval type-2 fuzzy-model-based systems

    CERN Document Server

    Li, Hongyi; Lam, Hak-Keung; Gao, Yabin

    2016-01-01

    This book develops a set of reference methods capable of modeling uncertainties existing in membership functions, and analyzing and synthesizing the interval type-2 fuzzy systems with desired performances. It also provides numerous simulation results for various examples, which fill certain gaps in this area of research and may serve as benchmark solutions for the readers. Interval type-2 T-S fuzzy models provide a convenient and flexible method for analysis and synthesis of complex nonlinear systems with uncertainties.

  3. Assessment of stochastic models for GPS measurements with different types of receivers

    Institute of Scientific and Technical Information of China (English)

    LI BoFeng; SHEN YunZhong; XU PeiLiang

    2008-01-01

    The stochastic model plays an important role in parameter estimation. The optimal estimator in the sense of least squares can only be obtained by using the correct stochastic model and consequently guarantees the precise positioning in GPS applications. In this contribution, the GPS measurements, collected by different types of geodetic dual-frequency receiver pairs on ultra-short baselines with a sampling interval of 1 s, are used to address their stochastic models, which include the variances of all observation types, the relationship between the observation accuracy and its elevation angle, the time correlation, as well as the correlation between observation types. The results show that the commonly used stochastic model with the assumption that all the raw GPS measurements are independent with the same variance does not meet the need for precise positioning and the elevation-dependent weight model cannot work well for different receiver and observation types. The time correlation and cross correlation are significant as well. It is therefore concluded that the stochastic model is much associ-ated with the receiver and observation types and should be specified for the receiver and observation types.

  4. Evaluation of Intercomparisons of Four Different Types of Model Simulating TWP-ICE

    Science.gov (United States)

    Petch, Jon; Hill, Adrian; Davies, Laura; Fridlind, Ann; Jakob, Christian; Lin, Yanluan; Xie, Shaoecheng; Zhu, Ping

    2013-01-01

    Four model intercomparisons were run and evaluated using the TWP-ICE field campaign, each involving different types of atmospheric model. Here we highlight what can be learnt from having single-column model (SCM), cloud-resolving model (CRM), global atmosphere model (GAM) and limited-area model (LAM) intercomparisons all based around the same field campaign. We also make recommendations for anyone planning further large multi-model intercomparisons to ensure they are of maximum value to the model development community. CRMs tended to match observations better than other model types, although there were exceptions such as outgoing long-wave radiation. All SCMs grew large temperature and moisture biases and performed worse than other model types for many diagnostics. The GAMs produced a delayed and significantly reduced peak in domain-average rain rate when compared to the observations. While it was shown that this was in part due to the analysis used to drive these models, the LAMs were also driven by this analysis and did not have the problem to the same extent. Based on differences between the models with parametrized convection (SCMs and GAMs) and those without (CRMs and LAMs), we speculate that that having explicit convection helps to constrain liquid water whereas the ice contents are controlled more by the representation of the microphysics.

  5. Connectionist models of artificial grammar learning: what type of knowledge is acquired?

    Science.gov (United States)

    Kinder, Annette; Lotz, Anja

    2009-09-01

    Two experiments are presented that test the predictions of two associative learning models of Artificial Grammar Learning. The two models are the simple recurrent network (SRN) and the competitive chunking (CC) model. The two experiments investigate acquisition of different types of knowledge in this task: knowledge of frequency and novelty of stimulus fragments (Experiment 1) and knowledge of letter positions, of small fragments, and of large fragments up to entire strings (Experiment 2). The results show that participants acquired all types of knowledge. Simulation studies demonstrate that the CC model explains the acquisition of all types of fragment knowledge but fails to account for the acquisition of positional knowledge. The SRN model, by contrast, accounts for the entire pattern of results found in the two experiments.

  6. A manufacturing quality assessment model based-on two stages interval type-2 fuzzy logic

    Science.gov (United States)

    Purnomo, Muhammad Ridwan Andi; Helmi Shintya Dewi, Intan

    2016-01-01

    This paper presents the development of an assessment models for manufacturing quality using Interval Type-2 Fuzzy Logic (IT2-FL). The proposed model is developed based on one of building block in sustainable supply chain management (SSCM), which is benefit of SCM, and focuses more on quality. The proposed model can be used to predict the quality level of production chain in a company. The quality of production will affect to the quality of product. Practically, quality of production is unique for every type of production system. Hence, experts opinion will play major role in developing the assessment model. The model will become more complicated when the data contains ambiguity and uncertainty. In this study, IT2-FL is used to model the ambiguity and uncertainty. A case study taken from a company in Yogyakarta shows that the proposed manufacturing quality assessment model can work well in determining the quality level of production.

  7. Muscle-tendon unit scaling methods of Hill-type musculoskeletal models: An overview.

    Science.gov (United States)

    Heinen, Frederik; Lund, Morten E; Rasmussen, John; de Zee, Mark

    2016-10-01

    This article gives an overview of the state of the art in scaling methods of generic Hill-type muscle model parameters in view of different applications and implementation of experimental data. This article establishes the requirements used to alter a generic model toward subject-specific musculoskeletal models. This article aims to improve model transparency by a structured description of scaling methods and the associated limitations in musculoskeletal models and highlight the importance of selecting a scaling method supporting the purpose of the model.

  8. Six missense mutations associated with type I and type II protein C deficiency and implications obtained from molecular modelling.

    Science.gov (United States)

    Zheng, Y Z; Sakata, T; Matsusue, T; Umeyama, H; Kato, H; Miyata, T

    1994-10-01

    The molecular basis of protein C deficiency was studied in three type I and three type II heterozygotes. Three probands showed thrombotic complications. All the exons and intron/exon junctions of the protein C gene were studied using a strategy combining by the polymerase chain reaction (PCR) amplification, single-strand conformational polymorphism (SSCP) analysis, and DNA sequencing of the PCR-amplified fragments. Six missense mutations were identified, including three novel ones. One was located in exon II, in which the initiating translation codon (ATG) encoding for Met at position -42 was replaced by ACG encoding for Thr. The other five were located in exon IX, and included TAC(Tyr399)-->CAC(His), CCG(Pro327)-->CTG(Leu), GAC(Asp359)-->AAC(Asn) in two cases, and GGG(Gly350)-->AGG(Arg). Four of the six missense mutations occurred in CG dinucleotide. Sequence analysis of the other exons excluded additional mutations. By restriction enzyme analysis, co-segregation of the mutation with protein C deficiency was observed in four families. The other two mutations at amino acid positions -42 and 350 were also considered to be associated with protein C deficiency due to the absence of these mutations in 50 normal individuals. A structural model of the protease domain of mutant activated protein C was constructed by the chimeric modelling method, and the resultant model suggested conformational changes due to each missense mutation identified in protein C deficiency. The present data also provide some evidence regarding the genetic heterogeneity of protein C deficiency.

  9. Abstract behavior types : a foundation model for components and their composition

    NARCIS (Netherlands)

    Arbab, F.

    2003-01-01

    The notion of Abstract Data Type (ADT) has served as a foundation model for structured and object oriented programming for some thirty years. The current trend in software engineering toward component based systems requires a foundation model as well. The most basic inherent property of an ADT, i.e.

  10. Assessment of Model Predictive and Adaptive Glucose Control Strategies for People with Type 1 Diabetes

    DEFF Research Database (Denmark)

    Boiroux, Dimitri; Duun-Henriksen, Anne Katrine; Schmidt, Signe;

    2014-01-01

    This paper addresses overnight blood glucose stabilization in people with type 1 diabetes using a Model Predictive Controller (MPC). We use a control strategy based on an adaptive ARMAX model in which we use a Recursive Extended Least Squares (RELS) method to estimate parameters of the stochastic...

  11. Assessment of Model Predictive and Adaptive Glucose Control Strategies for People with Type 1 Diabetes

    DEFF Research Database (Denmark)

    Boiroux, Dimitri; Duun-Henriksen, Anne Katrine; Schmidt, Signe

    2014-01-01

    This paper addresses overnight blood glucose stabilization in people with type 1 diabetes using a Model Predictive Controller (MPC). We use a control strategy based on an adaptive ARMAX model in which we use a Recursive Extended Least Squares (RELS) method to estimate parameters of the stochastic...

  12. Some Cautionary Notes on the Specification and Interpretation of LISREL-type Structural Equation Models.

    Science.gov (United States)

    Baldwin, Beatrice

    LISREL-type structural equation modeling is a powerful statistical technique that seems appropriate for social science variables which are complex and difficult to measure. The literature on the specification, estimation, and testing of such models is voluminous. The greatest proportion of this literature, however, focuses on the technical aspects…

  13. A new isotropic vector Preisach-type model of hysteresis and its identification

    Energy Technology Data Exchange (ETDEWEB)

    Mayergoyz, I.D.; Adly, A.A. (Univ. of Maryland, College Park, MD (United States))

    1993-11-01

    A new vector isotropic Preisach-type model of hysteresis is introduced and the identification problem for this model is posed. A mathematical machinery for the solution of the identification problem by using ''scalar'' and ''rotational'' experimental data is presented.

  14. Asteroseismic modelling of the solar-type subgiant star β Hydri

    DEFF Research Database (Denmark)

    Brandão, I.M.; Dogan, Gülnur; Christensen-Dalsgaard, Jørgen;

    2011-01-01

    the surface layers of stars. Because β Hydri is an evolved solar-type pulsator with mixed modes in its frequency spectrum, it is very interesting for asteroseismic studies. Aims: The goal of the present work is to search for a representative model of the solar-type star β Hydri, based on up-to-date non...... and different physics, using the stellar evolutionary code ASTEC. For the models that are inside the observed error box of β Hydri, we computed their frequencies with the pulsation code ADIPLS. We used two approaches to find the model that oscillates with the frequencies that are closest to the observed...

  15. A simple model to estimate the optimal doping of p - Type oxide superconductors

    Directory of Open Access Journals (Sweden)

    Adir Moysés Luiz

    2008-12-01

    Full Text Available Oxygen doping of superconductors is discussed. Doping high-Tc superconductors with oxygen seems to be more efficient than other doping procedures. Using the assumption of double valence fluctuations, we present a simple model to estimate the optimal doping of p-type oxide superconductors. The experimental values of oxygen content for optimal doping of the most important p-type oxide superconductors can be accounted for adequately using this simple model. We expect that our simple model will encourage further experimental and theoretical researches in superconducting materials.

  16. Spatially Homogeneous Bianchi Type V Cosmological Model in the Scale-Covariant Theory of Gravitation

    Institute of Scientific and Technical Information of China (English)

    Shri Ram; M.K.Verma; Mohd.Zeyauddin

    2009-01-01

    We discuss spatially homogeneous and anisotropic Bianchi type-V spacetime filled with a perfect fluid in the framework of the scaie-covariant theory of gravitation proposed by Canuto et al.By applying the law of variation for Hubble's parameter,exact solutions of the field equations are obtained,which correspond to the model of the universe having a big-bang type singularity at the initial time t=0.The cosmological model,evolving from the initial singularity,expands with power-law expansion and gives essentially an empty space for a large time.The physical and dynamical properties of the model are also discussed.

  17. Critical behavior of Gaussian model on diamond-type hierarchical lattices

    Institute of Scientific and Technical Information of China (English)

    孔祥木; 李崧

    1999-01-01

    It is proposed that the Gaussian type distribution constant bqi in the Gaussian model depends on the coordination number qi of site i, and that the relation bqi/bqj = qi/qj holds among bqi’s. The Gaussian model is then studied on a family of the diamond-type hierarchical (or DH) lattices, by the decimation real-space renormalization group following spin-resealing method. It is found that the magnetic property of the Gaussian model belongs to the same universal class, and that the critical point K* and the critical exponent v are given by K*= bqi/qi and v=1/2, respectively.

  18. Model-Independent Reconstruction of the Expansion History of the Universe from Type Ia Supernovae

    CERN Document Server

    Benitez-Herrera, S; Hillebrandt, W; Mignone, C; Bartelmann, M; Weller, J

    2011-01-01

    Based on the largest homogeneously reduced set of Type Ia supernova luminosity data currently available -- the Union2 sample -- we reconstruct the expansion history of the Universe in a model-independent approach. Our method tests the geometry of the Universe directly without reverting to any assumptions made on its energy content. This allows us to constrain Dark Energy models and non-standard cosmologies in a straightforward way. The applicability of the presented method is not restricted to testing cosmological models. It can be a valuable tool for pointing out systematic errors hidden in the supernova data and planning future Type Ia supernova cosmology campaigns.

  19. Models of spherical shells as sources of Majumdar-Papapetrou type spacetimes

    CERN Document Server

    García-Reyes, Gonzalo

    2016-01-01

    By starting with a seed Newtonian potential-density pair we construct relativistic thick spherical shell models for a Majumdar-Papapetrou type conformastatic spacetime. As simple example, we considerer a family of Plummer type relativistic spherical shells. These objects are then used to model a system composite by a dust disk and a halo of matter. We study the equatorial circular motion of test particles around the structures. Also the stability of the orbits is analyzed for radial perturbation using an extension of the Rayleigh criterion. The models considered satisfying all the energy conditions.

  20. Models of Particle Physics from Type IIB String Theory and F-theory: A Review

    CERN Document Server

    Maharana, Anshuman

    2012-01-01

    We review particle physics model building in type IIB string theory and F-theory. This is a region in the landscape where in principle many of the key ingredients required for a realistic model of particle physics can be combined successfully. We begin by reviewing moduli stabilisation within this framework and its implications for supersymmetry breaking. We then review model building tools and developments in the weakly coupled type IIB limit, for both local D3-branes at singularities and global models of intersecting D7-branes. Much of recent model building work has been in the strongly coupled regime of F-theory due to the presence of exceptional symmetries which allow for the construction of phenomenologically appealing Grand Unified Theories. We review both local and global F-theory model building starting from the fundamental concepts and tools regarding how the gauge group, matter sector and operators arise, and ranging to detailed phenomenological properties explored in the literature.

  1. Development of a Coronary Heart Disease Risk Prediction Model for Type 1 Diabetes: The Pittsburgh CHD in Type 1 Diabetes Risk Mode

    NARCIS (Netherlands)

    Zgibor, J.C.; Ruppert, K.; Orchard, T.J.; Soedamah-Muthu, S.S.; Fuller, J.H.; Chaturvedi, N.; Roberts, M.S.

    2010-01-01

    Aim - To create a coronary heart disease (CHD) risk prediction model specific to type 1 diabetes. Methods - Development of the model used data from the Pittsburgh Epidemiology of Diabetes Complications Study (EDC). EDC subjects had type 1 diabetes diagnosed between 1950 and 1980, received their

  2. Modeling type 1 and type 2 diabetes mellitus incidence in youth: an application of Bayesian hierarchical regression for sparse small area data.

    Science.gov (United States)

    Song, Hae-Ryoung; Lawson, Andrew; D'Agostino, Ralph B; Liese, Angela D

    2011-03-01

    Sparse count data violate assumptions of traditional Poisson models due to the excessive amount of zeros, and modeling sparse data becomes challenging. However, since aggregation to reduce sparseness may result in biased estimates of risk, solutions need to be found at the level of disaggregated data. We investigated different statistical approaches within a Bayesian hierarchical framework for modeling sparse data without aggregation of data. We compared our proposed models with the traditional Poisson model and the zero-inflated model based on simulated data. We applied statistical models to type 1 and type 2 diabetes in youth 10-19 years known as rare diseases, and compared models using the inference results and various model diagnostic tools. We showed that one of the models we proposed, a sparse Poisson convolution model, performed better than other models in the simulation and application based on the deviance information criterion (DIC) and the mean squared prediction error.

  3. Pattern of Stress-Induced Hyperglycemia according to Type of Diabetes: A Predator Stress Model

    Directory of Open Access Journals (Sweden)

    Jin-Sun Chang

    2013-12-01

    Full Text Available BackgroundWe aimed to quantify stress-induced hyperglycemia and differentiate the glucose response between normal animals and those with diabetes. We also examined the pattern in glucose fluctuation induced by stress according to type of diabetes.MethodsTo load psychological stress on animal models, we used a predator stress model by exposing rats to a cat for 60 minutes and measured glucose level from the beginning to the end of the test to monitor glucose fluctuation. We induced type 1 diabetes model (T1D for ten Sprague-Dawley rats using streptozotocin and used five Otsuka Long-Evans Tokushima Fatty rats as obese type 2 diabetes model (OT2D and 10 Goto-Kakizaki rats as nonobese type 2 diabetes model (NOT2D. We performed the stress loading test in both the normal and diabetic states and compared patterns of glucose fluctuation among the three models. We classified the pattern of glucose fluctuation into A, B, and C types according to speed of change in glucose level.ResultsIncrease in glucose, total amount of hyperglycemic exposure, time of stress-induced hyperglycemia, and speed of glucose increase were significantly increased in all models compared to the normal state. While the early increase in glucose after exposure to stress was higher in T1D and NOT2D, it was slower in OT2D. The rate of speed of the decrease in glucose level was highest in NOT2D and lowest in OT2D.ConclusionThe diabetic state was more vulnerable to stress compared to the normal state in all models, and the pattern of glucose fluctuation differed among the three types of diabetes. The study provides basic evidence for stress-induced hyperglycemia patterns and characteristics used for the management of diabetes patients.

  4. A BAYESIAN HIERARCHICAL SPATIAL POINT PROCESS MODEL FOR MULTI-TYPE NEUROIMAGING META-ANALYSIS.

    Science.gov (United States)

    Kang, Jian; Nichols, Thomas E; Wager, Tor D; Johnson, Timothy D

    2014-09-01

    Neuroimaging meta-analysis is an important tool for finding consistent effects over studies that each usually have 20 or fewer subjects. Interest in meta-analysis in brain mapping is also driven by a recent focus on so-called "reverse inference": where as traditional "forward inference" identifies the regions of the brain involved in a task, a reverse inference identifies the cognitive processes that a task engages. Such reverse inferences, however, requires a set of meta-analysis, one for each possible cognitive domain. However, existing methods for neuroimaging meta-analysis have significant limitations. Commonly used methods for neuroimaging meta-analysis are not model based, do not provide interpretable parameter estimates, and only produce null hypothesis inferences; further, they are generally designed for a single group of studies and cannot produce reverse inferences. In this work we address these limitations by adopting a non-parametric Bayesian approach for meta analysis data from multiple classes or types of studies. In particular, foci from each type of study are modeled as a cluster process driven by a random intensity function that is modeled as a kernel convolution of a gamma random field. The type-specific gamma random fields are linked and modeled as a realization of a common gamma random field, shared by all types, that induces correlation between study types and mimics the behavior of a univariate mixed effects model. We illustrate our model on simulation studies and a meta analysis of five emotions from 219 studies and check model fit by a posterior predictive assessment. In addition, we implement reverse inference by using the model to predict study type from a newly presented study. We evaluate this predictive performance via leave-one-out cross validation that is efficiently implemented using importance sampling techniques.

  5. Sensitivity Analysis on LOCCW of Westinghouse typed Reactors Considering WOG2000 RCP Seal Leakage Model

    Energy Technology Data Exchange (ETDEWEB)

    Na, Jang-Hwan; Jeon, Ho-Jun; Hwang, Seok-Won [KHNP Central Research Institute, Daejeon (Korea, Republic of)

    2015-10-15

    In this paper, we focus on risk insights of Westinghouse typed reactors. We identified that Reactor Coolant Pump (RCP) seal integrity is the most important contributor to Core Damage Frequency (CDF). As we reflected the latest technical report; WCAP-15603(Rev. 1-A), 'WOG2000 RCP Seal Leakage Model for Westinghouse PWRs' instead of the old version, RCP seal integrity became more important to Westinghouse typed reactors. After Fukushima accidents, Korea Hydro and Nuclear Power (KHNP) decided to develop Low Power and Shutdown (LPSD) Probabilistic Safety Assessment (PSA) models and upgrade full power PSA models of all operating Nuclear Power Plants (NPPs). As for upgrading full power PSA models, we have tried to standardize the methodology of CCF (Common Cause Failure) and HRA (Human Reliability Analysis), which are the most influential factors to risk measures of NPPs. Also, we have reviewed and reflected the latest operating experiences, reliability data sources and technical methods to improve the quality of PSA models. KHNP has operating various types of reactors; Optimized Pressurized Reactor (OPR) 1000, CANDU, Framatome and Westinghouse. So, one of the most challengeable missions is to keep the balance of risk contributors of all types of reactors. This paper presents the method of new RCP seal leakage model and the sensitivity analysis results from applying the detailed method to PSA models of Westinghouse typed reference reactors. To perform the sensitivity analysis on LOCCW of the reference Westinghouse typed reactors, we reviewed WOG2000 RCP seal leakage model and developed the detailed event tree of LOCCW considering all scenarios of RCP seal failures. Also, we performed HRA based on the T/H analysis by using the leakage rates for each scenario. We could recognize that HRA was the sensitive contributor to CDF, and the RCP seal failure scenario of 182gpm leakage rate was estimated as the most important scenario.

  6. Input modeling with phase-type distributions and Markov models theory and applications

    CERN Document Server

    Buchholz, Peter; Felko, Iryna

    2014-01-01

    Containing a summary of several recent results on Markov-based input modeling in a coherent notation, this book introduces and compares algorithms for parameter fitting and gives an overview of available software tools in the area. Due to progress made in recent years with respect to new algorithms to generate PH distributions and Markovian arrival processes from measured data, the models outlined are useful alternatives to other distributions or stochastic processes used for input modeling. Graduate students and researchers in applied probability, operations research and computer science along with practitioners using simulation or analytical models for performance analysis and capacity planning will find the unified notation and up-to-date results presented useful. Input modeling is the key step in model based system analysis to adequately describe the load of a system using stochastic models. The goal of input modeling is to find a stochastic model to describe a sequence of measurements from a real system...

  7. St\\"ackel-type dynamic model of the Galaxy based on maser kinematic data

    CERN Document Server

    Gromov, A O; Ossipkov, L P

    2016-01-01

    A dynamic model of the Galaxy is constructed based on kinematic data for masers with trigonometric parallaxes. Maser data is used to compute the model potential in the Galactic plane. The potential is then generalized to three dimensions assuming the existence of a third quadratic integral of motion. The resulting Galactic model potential is of St\\"ackel's type. The corresponding space density function is determined from Poisson's equation.

  8. A Type II Diabetic Model-from Insulin Resistance to Diabetes

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    1 IntroductionWith the development of the living standard of the people, the incidence rate of diabetes, especially type II diabetes, increase with years. Establishment of corresponding animal model has become one of the important tool investigating diabetes. Diabetic animal model is classified roughly into experimental and spontaneous diabetic animal model. The spontaneous one has a relatively high applied value. However, its extensive application has been restricted by some factors such as costliness and ...

  9. Bianchi type VI1 cosmological model with wet dark fluid in scale invariant theory of gravitation

    CERN Document Server

    Mishra, B

    2014-01-01

    In this paper, we have investigated Bianchi type VIh, II and III cosmological model with wet dark fluid in scale invariant theory of gravity, where the matter field is in the form of perfect fluid and with a time dependent gauge function (Dirac gauge). A non-singular model for the universe filled with disorder radiation is constructed and some physical behaviors of the model are studied for the feasible VIh (h = 1) space-time.

  10. Implementation of magnetostriction Preisach-type models using orthogonally coupled hysteresis operators

    Energy Technology Data Exchange (ETDEWEB)

    Adly, A.A. [Electrical Power and Machines Department, Faculty of Engineering, Cairo University, Giza 12211 (Egypt)], E-mail: adlyamr@gmail.com; Abd-El-Hafiz, S.K. [Department of Engineering Mathematics, Faculty of Engineering, Cairo University, Giza 12211 (Egypt)], E-mail: salwahafiz@link.net

    2008-02-01

    Magnetic materials exhibiting gigantic magnetostriction are currently being used in various actuator devices and vibration damping applications. Recently, a new family of efficient Preisach-type vector hysteresis models having coupled elementary operators has been introduced. The purpose of this paper is to extend the applicability of those recently introduced models to magnetostriction simulation. Details of the model, its identification, and experimental testing are presented in the paper.

  11. Utilizing anisotropic Preisach-type models in the accurate simulation of magnetostriction

    Energy Technology Data Exchange (ETDEWEB)

    Adly, A.A. [Cairo Univ., Giza (Egypt). Electrical Power and Machines Dept.; Mayergoyz, I.D. [Univ. of Maryland, College Park, MD (United States). Electrical Engineering Dept.; Bergqvist, A. [Royal Inst. of Tech., Stockholm (Sweden). Dept. of Electrical Power Engineering

    1997-09-01

    Magnetostriction models are being widely used in the development of fine positioning and active vibration damping devices. This paper presents a new approach for simulating 1-D magnetostriction using 2-D anisotropic Preisach-type models. In this approach, identification of the model takes into account measured flux density versus field and strain versus field curves for different stress values. Consequently, a more accurate magnetostriction model may be obtained. Details of the identification procedure as well as experimental testing of the proposed model are given.

  12. A Beddoes-Leishman type dynamic stall model in state-space and indicial formulations

    DEFF Research Database (Denmark)

    Hansen, M.H.; Gaunaa, Mac; Aagaard Madsen, Helge

    2004-01-01

    This report contains a description of a Beddoes-Leishman type dynamic stall model in both a state-space and an indicial function formulation. The model predicts the unsteady aerodynamic forces and moment on an airfoil section undergoing arbitrary motionin heave, lead-lag, and pitch. The model...... features, such as overshoot of the lift, in the stall region. The linearized model is shown to give identicalresults to the full model for small amplitude oscillations. Furthermore, it is shown that the response of finite thichkness airfoils can be reproduced to a high accuracy by the use of specific...

  13. Biomechanical analysis of four types of internal fixation in subtrochanteric fracture models.

    Science.gov (United States)

    Wang, Jie; Ma, Xin-long; Ma, Jian-xiong; Xing, Dan; Yang, Yang; Zhu, Shao-wen; Ma, Bao-yi; Chen, Yang; Feng, Rui; Jia, Hao-bo; Yu, Jing-tao

    2014-05-01

    To compare the biomechanical properties of four types of internal fixation (proximal femoral nail [PFN], dynamic hip screw [DHS], dynamic condylar screw [DCS], and proximal femoral locking plate [PFLP]) for different types of subtrochanteric fractures. Thirty-two antiseptic femurs were randomly divided into four groups. After internal fixation had been implanted, different types of subtrochanteric fracture models were produced and each tested under vertical, torsional and vertical damage loads. The stiffness ratio of PFN in each fracture model and failure load were the highest in the four groups; however, the torsional stiffness ratio was the lowest. Tension strain ratios of DHS and DCS on the lateral side became compression strain ratios with restoration of the medial fragment. The stiffness ratio of DHS was lower than PFLP in each fracture model, torsional stiffness ratio was the highest in fracture models II to V and the failure load was lower only than PFN. The stiffness ratio and failure load of DCS were both the lowest, torsional stiffness ratio was similar to PFLP's in fracture models II to V. The stiffness ratio of PFLP was only lower than PFN's in each fracture model, but the failure load was lower than DHS's. Four types of internal fixation achieve better stabilities for type I subtrochanteric fractures. PFN and PFLP produce reliable stability in type IIIA subtrochanteric fractures. If the medial buttress is restored, DCS can be considered. For type IV subtrochanteric fractures, only PFN provides stable fixation. PFLP is suitable for comminuted fractures with large fragments. © 2014 Chinese Orthopaedic Association and Wiley Publishing Asia Pty Ltd.

  14. Increased recruitment but impaired function of leukocytes during inflammation in mouse models of type 1 and type 2 diabetes.

    Directory of Open Access Journals (Sweden)

    Ulrika Sofia Pettersson

    Full Text Available BACKGROUND: Patients suffering from diabetes show defective bacterial clearance. This study investigates the effects of elevated plasma glucose levels during diabetes on leukocyte recruitment and function in established models of inflammation. METHODOLOGY/PRINCIPAL FINDINGS: Diabetes was induced in C57Bl/6 mice by intravenous alloxan (causing severe hyperglycemia, or by high fat diet (moderate hyperglycemia. Leukocyte recruitment was studied in anaesthetized mice using intravital microscopy of exposed cremaster muscles, where numbers of rolling, adherent and emigrated leukocytes were quantified before and during exposure to the inflammatory chemokine MIP-2 (0.5 nM. During basal conditions, prior to addition of chemokine, the adherent and emigrated leukocytes were increased in both alloxan- (62±18% and 85±21%, respectively and high fat diet-induced (77±25% and 86±17%, respectively diabetes compared to control mice. MIP-2 induced leukocyte emigration in all groups, albeit significantly more cells emigrated in alloxan-treated mice (15.3±1.0 compared to control (8.0±1.1 mice. Bacterial clearance was followed for 10 days after subcutaneous injection of bioluminescent S. aureus using non-invasive IVIS imaging, and the inflammatory response was assessed by Myeloperoxidase-ELISA and confocal imaging. The phagocytic ability of leukocytes was assessed using LPS-coated fluorescent beads and flow cytometry. Despite efficient leukocyte recruitment, alloxan-treated mice demonstrated an impaired ability to clear bacterial infection, which we found correlated to a 50% decreased phagocytic ability of leukocytes in diabetic mice. CONCLUSIONS/SIGNIFICANCE: These results indicate that reduced ability to clear bacterial infections observed during experimentally induced diabetes is not due to reduced leukocyte recruitment since sustained hyperglycemia results in increased levels of adherent and emigrated leukocytes in mouse models of type 1 and type 2 diabetes

  15. A New Approach for Modeling Darrieus-Type Vertical Axis Wind Turbine Rotors Using Electrical Equivalent Circuit Analogy: Basis of Theoretical Formulations and Model Development

    National Research Council Canada - National Science Library

    Pierre Tchakoua; Rene Wamkeue; Mohand Ouhrouche; Tommy Andy Tameghe; Gabriel Ekemb

    2015-01-01

    .... Thus, models can significantly reduce design, development and optimization costs. This paper proposes a novel equivalent electrical model for Darrieus-type vertical axis wind turbines (DTVAWTs...

  16. The ARIC predictive model reliably predicted risk of type II diabetes in Asian populations

    Directory of Open Access Journals (Sweden)

    Chin Calvin

    2012-04-01

    Full Text Available Abstract Background Identification of high-risk individuals is crucial for effective implementation of type 2 diabetes mellitus prevention programs. Several studies have shown that multivariable predictive functions perform as well as the 2-hour post-challenge glucose in identifying these high-risk individuals. The performance of these functions in Asian populations, where the rise in prevalence of type 2 diabetes mellitus is expected to be the greatest in the next several decades, is relatively unknown. Methods Using data from three Asian populations in Singapore, we compared the performance of three multivariate predictive models in terms of their discriminatory power and calibration quality: the San Antonio Health Study model, Atherosclerosis Risk in Communities model and the Framingham model. Results The San Antonio Health Study and Atherosclerosis Risk in Communities models had better discriminative powers than using only fasting plasma glucose or the 2-hour post-challenge glucose. However, the Framingham model did not perform significantly better than fasting glucose or the 2-hour post-challenge glucose. All published models suffered from poor calibration. After recalibration, the Atherosclerosis Risk in Communities model achieved good calibration, the San Antonio Health Study model showed a significant lack of fit in females and the Framingham model showed a significant lack of fit in both females and males. Conclusions We conclude that adoption of the ARIC model for Asian populations is feasible and highly recommended when local prospective data is unavailable.

  17. Type Ia Supernova Modeling with Spectrophotometric Data from the Nearby Supernova Factory

    Science.gov (United States)

    Saunders, Clare; Nearby Supernova Factory

    2017-01-01

    Type Ia supernova cosmology is currently limited by dispersion in standardized magnitudes, driven by a combination of calibration uncertainty and so-called ‘intrinsic dispersion.' This intrinsic dispersion is caused by supernova behavior that the current lightcurve fitters do not account for, and it can involve systematic trends. Using data from the Nearby Supernova Factory, we have developed an empirical model that captures a wider range of Type Ia supernova behavior and can be used to improve standardized magnitude dispersion. To do this, Gaussian Processes and Expectation Maximization Factor Analysis are used to generate spectral time series templates that can be combined linearly. Variations of this model are optimized, alternatively for supernova standardization or for maximum accuracy in the description of supernova spectral features. We present these models along with interpretation of the model components. Methods are discussed for the most efficient application of the models in cosmological surveys.

  18. A comprehensive compartmental model of blood glucose regulation for healthy and type 2 diabetic subjects

    DEFF Research Database (Denmark)

    Vahidi, O; Kwok, K E; Gopaluni, R B

    2016-01-01

    We have expanded a former compartmental model of blood glucose regulation for healthy and type 2 diabetic subjects. The former model was a detailed physiological model which considered the interactions of three substances, glucose, insulin and glucagon on regulating the blood sugar. The main...... drawback of the former model was its restriction on the route of glucose entrance to the body which was limited to the intravenous glucose injection. To handle the oral glucose intake, we have added a model of glucose absorption in the gastrointestinal tract to the former model to address the resultant...... variations of blood glucose concentrations following an oral glucose intake. Another model representing the incretins production in the gastrointestinal tract along with their hormonal effects on boosting pancreatic insulin production is also added to the former model. We have used two sets of clinical data...

  19. Glycogen Storage Disease Type Ia in Canines: A Model for Human Metabolic and Genetic Liver Disease

    Directory of Open Access Journals (Sweden)

    Andrew Specht

    2011-01-01

    Full Text Available A canine model of Glycogen storage disease type Ia (GSDIa is described. Affected dogs are homozygous for a previously described M121I mutation resulting in a deficiency of glucose-6-phosphatase-α. Metabolic, clinicopathologic, pathologic, and clinical manifestations of GSDIa observed in this model are described and compared to those observed in humans. The canine model shows more complete recapitulation of the clinical manifestations seen in humans including “lactic acidosis”, larger size, and longer lifespan compared to other animal models. Use of this model in preclinical trials of gene therapy is described and briefly compared to the murine model. Although the canine model offers a number of advantages for evaluating potential therapies for GSDIa, there are also some significant challenges involved in its use. Despite these challenges, the canine model of GSDIa should continue to provide valuable information about the potential for generating curative therapies for GSDIa as well as other genetic hepatic diseases.

  20. Certain Type Turbofan Engine Whole Vibration Model with Support Looseness Fault and Casing Response Characteristics

    Directory of Open Access Journals (Sweden)

    H. F. Wang

    2014-01-01

    Full Text Available Support looseness fault is a type of common fault in aeroengine. Serious looseness fault would emerge under larger unbalanced force, which would cause excessive vibration and even lead to rubbing fault, so it is important to analyze and recognize looseness fault effectively. In this paper, based on certain type turbofan engine structural features, a rotor-support-casing whole model for certain type turbofan aeroengine is established. The rotor and casing systems are modeled by means of the finite element beam method; the support systems are modeled by lumped-mass model; the support looseness fault model is also introduced. The coupled system response is obtained by numerical integral method. In this paper, based on the casing acceleration signals, the impact characteristics of symmetrical stiffness and asymmetric stiffness models are analyzed, finding that the looseness fault would lead to the longitudinal asymmetrical characteristics of acceleration time domain wave and the multiple frequency characteristics, which is consistent with the real trial running vibration signals. Asymmetric stiffness looseness model is verified to be fit for aeroengine looseness fault model.

  1. Rotating models of young solar-type stars : Exploring braking laws and angular momentum transport processes

    CERN Document Server

    Amard, Louis; Charbonnel, Corinne; Gallet, Florian; Bouvier, Jérôme

    2016-01-01

    We study the predicted rotational evolution of solar-type stars from the pre-main sequence to the solar age with 1D rotating evolutionary models including physical ingredients. We computed rotating evolution models of solar-type stars including an external stellar wind torque and internal transport of angular momentum following the method of Maeder and Zahn with the code STAREVOL. We explored different formalisms and prescriptions available from the literature. We tested the predictions of the models against recent rotational period data from extensive photometric surveys, lithium abundances of solar-mass stars in young clusters, and the helioseismic rotation profile of the Sun. We find a best-matching combination of prescriptions for both internal transport and surface extraction of angular momentum. This combination provides a very good fit to the observed evolution of rotational periods for solar-type stars from early evolution to the age of the Sun. Additionally, we show that fast rotators experience a st...

  2. Characterization and modelling of the boron-oxygen defect activation in compensated n-type silicon

    Energy Technology Data Exchange (ETDEWEB)

    Schön, J.; Niewelt, T.; Broisch, J.; Warta, W.; Schubert, M. C. [Fraunhofer Institute for Solar Energy Systems ISE, Heidenhofstr. 2, 79110 Freiburg (Germany)

    2015-12-28

    A study of the activation of the light-induced degradation in compensated n-type Czochralski grown silicon is presented. A kinetic model is established that verifies the existence of both the fast and the slow components known from p-type and proves the quadratic dependence of the defect generation rates of both defects on the hole concentration. The model allows for the description of lifetime degradation kinetics in compensated n-type silicon under various intensities and is in accordance with the findings for p-type silicon. We found that the final concentrations of the slow defect component in compensated n-type silicon only depend on the interstitial oxygen concentration and on neither the boron concentration nor the equilibrium electron concentration n{sub 0}. The final concentrations of the fast defect component slightly increase with increasing boron concentration. The results on n-type silicon give new insight to the origin of the BO defect and question the existing models for the defect composition.

  3. Model-aided radiometric determination of photolysis frequencies in a sunlit atmosphere simulation chamber

    Directory of Open Access Journals (Sweden)

    B. Bohn

    2004-10-01

    Full Text Available In this work diurnal and seasonal variations of mean photolysis frequencies for the atmosphere simulation chamber SAPHIR at Forschungszentrum Jülich are calculated. SAPHIR has a complex construction with UV permeable teflon walls allowing natural sunlight to enter the reactor volume. The calculations are based on external measurements of solar spectral actinic flux and a model considering the time-dependent impact of shadows from construction elements as well as the influence of the teflon walls. Overcast and clear-sky conditions are treated in a consistent way and different assumptions concerning diffuse sky radiance distributions are tested. Radiometric measurements inside the chamber are used for an inspection of model predictions. Under overcast conditions we obtain 74% and 67% of external values for photolysis frequencies j(NO2 (NO2+hν→NO+O(3P and j(O1D (O3+hν→O2+O(1D, respectively. On a clear sky summer day these values are time-dependent within ranges 0.65–0.86 and 0.60–0.73, for j(NO2 and j(O1D, respectively. A succeeding paper (Bohn et al., 2004 is dealing with an on-road test of the model approach by comparison with photolysis frequencies from chemical actinometry experiments within SAPHIR.

  4. Integrable, molecular-type solutions of the extended Skyrme-Faddeev model

    CERN Document Server

    Sawado, Nobuyuki

    2013-01-01

    We construct molecular type vortex solutions in the integrable sector of the extended Skyrme-Faddeev (ESF) model.The solutions are a holomorphic type which satisfies the zero curvature condition.For some constrained values of the coupling constants, special vortex solutions exist.For other values, special forms of the potential are employed for the stability of the molecular type solution.The solutions satisfy the zero curvature condition, and then they necessarily have an infinite number of conserved current. We numerically check their existence in terms of the simulated annealing method.

  5. Constraints from Type Ia supernovae on the Λ-CDM model in Randers-Finsler space

    Institute of Scientific and Technical Information of China (English)

    CHANG Zhe; LI Ming-Hua; LI Xin

    2012-01-01

    Gravitational field equations in Randers-Finsler space of approximate Berwald type are investigated.A modified Friedmann equation and a new luminosity distance-redshift relation is proposed.A best-fit to the Type Ia supernovae (SNe) observations yields that the ΩΛ in the Λ-CDM model is suppressed to almost zero.This fact indicates that the astronomical observations on the Type Ia SNe can be described well without invoking any form of dark energy.The best-fit age of the universe is given.It is in agreement with the age of our galaxy.

  6. Impact of Diabetes Education Based on Type 1 Diabetes management model

    OpenAIRE

    Ocakçı, Ayşe Ferda

    2015-01-01

    ORIGINAL ARTICLE Impact of education based on type 1 diabetes management model Çağrı Çövener Özçelik & Ayşe Ferda Ocakçı Received: 27 September 2012 /Accepted: 30 December 2014 /Published online: 18 February 2015 # Research Society for Study of Diabetes in India 2015 Abstract The diabetes management is considered to be ad-versely affected when adolescent-specific education methods are not used. In this study, Type 1 Diabetes Management Model which ensures standardis...

  7. LRS Bianchi Type II Massive String Cosmological Models with Magnetic Field in Lyra's Geometry

    Directory of Open Access Journals (Sweden)

    Raj Bali

    2013-01-01

    Full Text Available Bianchi type II massive string cosmological models with magnetic field and time dependent gauge function ( in the frame work of Lyra's geometry are investigated. The magnetic field is in -plane. To get the deterministic solution, we have assumed that the shear ( is proportional to the expansion (. This leads to , where and are metric potentials and is a constant. We find that the models start with a big bang at initial singularity and expansion decreases due to lapse of time. The anisotropy is maintained throughout but the model isotropizes when . The physical and geometrical aspects of the model in the presence and absence of magnetic field are also discussed.

  8. Perfect fluid Bianchi Type-I cosmological models with time varying and

    Indian Academy of Sciences (India)

    J P Singh; R K Tiwari

    2008-04-01

    Bianchi Type-I cosmological models containing perfect fluid with time varying and have been presented. The solutions obtained represent an expansion scalar bearing a constant ratio to the anisotropy in the direction of space-like unit vector . Of the two models obtained, one has negative vacuum energy density, which decays numerically. In this model, we obtain ∼ 2, ∼ 44/ and ∼ -2 ( is the cosmic time) which is in accordance with the main dynamical laws for the decay of . The second model reduces to a static solution with repulsive gravity.

  9. Mathematical modeling taking into account of intrinsic kinetic properties of cylinder-type vanadium catalyst

    Institute of Scientific and Technical Information of China (English)

    陈振兴; 李洪桂; 王零森

    2004-01-01

    The method to calculate internal surface effective factor of cylinder-type vanadium catalyst Ls-9 was given. Based on hypothesis of subjunctive one dimension diffusion and combined shape adjustment factor with threestep catalytic mechanism model, the macroscopic kinetic model equation about SO2 oxidation on Ls-9 was deduced.With fixed-bed integral reactor and under the conditions of temperature 350 - 410 ℃, space velocity 1 800 - 5 000h-1, SO2 inlet content 7 %- 12%, the macroscopic kinetic data were detected. Through model parameter estimation,the macroscopic kinetic model equation was obtained.

  10. Bianchi Type Ⅲ Bulk Viscous Barotropic Fluid Cosmological Models with Variable G and A

    Institute of Scientific and Technical Information of China (English)

    Raj Ba-li; Seema Tinker

    2009-01-01

    Bianchi type-Ⅲ bulk viscous barotropic fluid cosmological model with variables G and A is investigated. To obtainthe realistic model, we assume the conditions between the metric potentials A, B, C as A/A = B/B = m1/tnand C/C = m2/tn, P = p - 3ηH, η= ηops, p =γp, 0 γ 1, where p is isotropic pressure, η the coefficient of bulk viscosity, ηo and S the constants, H the Hubble constant, m1= 2m2 where m1 0, m2 0. The solutions obtained lead to inflationary phase and the results obtained match with the observations. The case n = 1 for S = 1 is also discussed, relating the results with the observations.PACS: 98. 80. Hω, 04.50. +h, 98.80. CqSpatially homogeneous and anisotropic cosmologi-cal models play a significant role in description of the large scale behaviour of the universe. The choice of anisotropic model in the Einstein system of field equa-tions permits us to obtain cosmological model more general than the Robertson-Walker model. Tikekar and Patel[1] have investigated some exact solutions of massive string for Bianchi type-Ⅲ spacetime in the presence and absence of magnetic field. They have also discussed the behaviour of the model in the ab-sence of magnetic field. Bali and Dave[2] investigated the Bianchi type-Ⅲ string cosmological model with bulk viscosity. Recently Bali and Pradhan[3] investi-gated the Bianchi type-Ⅲ string cosmological models with time-dependent bulk viscosity.

  11. Review on the HVAC System Modeling Types and the Shortcomings of Their Application

    Directory of Open Access Journals (Sweden)

    Raad Z. Homod

    2013-01-01

    Full Text Available The modeling of the heating, ventilation, and air conditioning (HVAC system is a prominent topic because of its relationship with energy savings and environmental, economical, and technological issues. The modeling of the HVAC system is concerned with the indoor thermal sensation, which is related to the modeling of building, air handling unit (AHU equipments, and indoor thermal processes. Until now, many HVAC system modeling approaches are made available, and the techniques have become quite mature. But there are some shortcomings in application and integration methods for the different types of the HVAC model. The application and integration processes will act to accumulate the defective characteristics for both AHU equipments and building models such as nonlinear, pure lag time, high thermal inertia, uncertain disturbance factors, large-scale systems, and constraints. This paper shows types of the HVAC model and the advantages and disadvantages for each application of them, and it finds out that the gray-box type is the best one to represent the indoor thermal comfort. But its application fails at the integration method where its response deviated to unreal behavior.

  12. Modeling the dissolution of various types of mixed energetic residues under different flow conditions.

    Science.gov (United States)

    Wang, Chao; Fuller, Mark E; Schaefer, Charles E; Fu, Dafang; Jin, Yan

    2012-10-15

    Energetic residues are scattered around active ranges due to the detonation events and dissolution is usually the first step for the entry of explosive compounds into the environment. The current models for describing the dissolution are subject to limitations in either model applicability or generality. This study attempted to develop a general model that is applicable to various types of energetic residues. Experimental data that were acquired from previous reports were used for testing the developed model. The results showed that the model captured well the dissolution processes of different types of energetic residues: 2,4,6-trinitrotoluene (TNT), Tritonal, Composition B, Octol, and Greener Insensitive Material (GIM). Moreover, it was observed that the mass transfer coefficients of TNT, hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX), and/or octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX) that were part of the energetic residues increased quantitatively with rising flow rates. In addition, the values of resistance coefficient, a model parameter, were negligible for the drop-impingement experiments, implying that under the conditions of rainfall and/or snowmelt flow, the surface attachment effect on the dissolution of energetic residues that rest on range soils is trivial. The study herein provides a general modeling approach for various types of energetic residues with additional insights in regards to their dissolution processes.

  13. Predicting polarization signatures for double-detonation and delayed-detonation models of Type Ia supernovae

    Science.gov (United States)

    Bulla, M.; Sim, S. A.; Kromer, M.; Seitenzahl, I. R.; Fink, M.; Ciaraldi-Schoolmann, F.; Röpke, F. K.; Hillebrandt, W.; Pakmor, R.; Ruiter, A. J.; Taubenberger, S.

    2016-10-01

    Calculations of synthetic spectropolarimetry are one means to test multidimensional explosion models for Type Ia supernovae. In a recent paper, we demonstrated that the violent merger of a 1.1 and 0.9 M⊙ white dwarf binary system is too asymmetric to explain the low polarization levels commonly observed in normal Type Ia supernovae. Here, we present polarization simulations for two alternative scenarios: the sub-Chandrasekhar mass double-detonation and the Chandrasekhar mass delayed-detonation model. Specifically, we study a 2D double-detonation model and a 3D delayed-detonation model, and calculate polarization spectra for multiple observer orientations in both cases. We find modest polarization levels (<1 per cent) for both explosion models. Polarization in the continuum peaks at ˜0.1-0.3 per cent and decreases after maximum light, in excellent agreement with spectropolarimetric data of normal Type Ia supernovae. Higher degrees of polarization are found across individual spectral lines. In particular, the synthetic Si II λ6355 profiles are polarized at levels that match remarkably well the values observed in normal Type Ia supernovae, while the low degrees of polarization predicted across the O I λ7774 region are consistent with the non-detection of this feature in current data. We conclude that our models can reproduce many of the characteristics of both flux and polarization spectra for well-studied Type Ia supernovae, such as SN 2001el and SN 2012fr. However, the two models considered here cannot account for the unusually high level of polarization observed in extreme cases such as SN 2004dt.

  14. Conclusions on motor control depend on the type of model used to represent the periphery.

    Science.gov (United States)

    Pinter, Ilona J; van Soest, Arthur J; Bobbert, Maarten F; Smeets, Jeroen B J

    2012-10-01

    Within the field of motor control, there is no consensus on which kinematic and kinetic aspects of movements are planned or controlled. Perturbing goal-directed movements is a frequently used tool to answer this question. To be able to draw conclusions about motor control from kinematic responses to perturbations, a model of the periphery (i.e., the skeleton, muscle-tendon complexes, and spinal reflex circuitry) is required. The purpose of the present study was to determine to what extent such conclusions depend on the level of simplification with which the dynamical properties of the periphery are modeled. For this purpose, we simulated fast goal-directed single-joint movement with four existing types of models. We tested how three types of perturbations affected movement trajectory if motor commands remained unchanged. We found that the four types of models of the periphery showed different robustness to the perturbations, leading to different predictions on how accurate motor commands need to be, i.e., how accurate the knowledge of external conditions needs to be. This means that when interpreting kinematic responses obtained in perturbation experiments the level of error correction attributed to adaptation of motor commands depends on the type of model used to describe the periphery.

  15. Video Modeling for Individuals with Autism: A Review of Model Types and Effects

    Science.gov (United States)

    McCoy, Kathleen; Hermansen, Emily

    2007-01-01

    Efficacy research on video modeling as an instructional approach for individuals with autism has been found to be a promising area for teachers and researchers. Over the last three decades the literature has shown successful use of video modeling for teaching a variety of social, academic, and functional skills. The purpose of this literature…

  16. The effects of numerical-model complexity and observation type on estimated porosity values

    Science.gov (United States)

    Starn, J. Jeffrey; Bagtzoglou, Amvrossios C.; Green, Christopher T.

    2015-09-01

    The relative merits of model complexity and types of observations employed in model calibration are compared. An existing groundwater flow model coupled with an advective transport simulation of the Salt Lake Valley, Utah (USA), is adapted for advective transport, and effective porosity is adjusted until simulated tritium concentrations match concentrations in samples from wells. Two calibration approaches are used: a "complex" highly parameterized porosity field and a "simple" parsimonious model of porosity distribution. The use of an atmospheric tracer (tritium in this case) and apparent ages (from tritium/helium) in model calibration also are discussed. Of the models tested, the complex model (with tritium concentrations and tritium/helium apparent ages) performs best. Although tritium breakthrough curves simulated by complex and simple models are very generally similar, and there is value in the simple model, the complex model is supported by a more realistic porosity distribution and a greater number of estimable parameters. Culling the best quality data did not lead to better calibration, possibly because of processes and aquifer characteristics that are not simulated. Despite many factors that contribute to shortcomings of both the models and the data, useful information is obtained from all the models evaluated. Although any particular prediction of tritium breakthrough may have large errors, overall, the models mimic observed trends.

  17. Large-scale Monte Carlo simulations for the depinning transition in Ising-type lattice models

    Science.gov (United States)

    Si, Lisha; Liao, Xiaoyun; Zhou, Nengji

    2016-12-01

    With the developed "extended Monte Carlo" (EMC) algorithm, we have studied the depinning transition in Ising-type lattice models by extensive numerical simulations, taking the random-field Ising model with a driving field and the driven bond-diluted Ising model as examples. In comparison with the usual Monte Carlo method, the EMC algorithm exhibits greater efficiency of the simulations. Based on the short-time dynamic scaling form, both the transition field and critical exponents of the depinning transition are determined accurately via the large-scale simulations with the lattice size up to L = 8912, significantly refining the results in earlier literature. In the strong-disorder regime, a new universality class of the Ising-type lattice model is unveiled with the exponents β = 0.304(5) , ν = 1.32(3) , z = 1.12(1) , and ζ = 0.90(1) , quite different from that of the quenched Edwards-Wilkinson equation.

  18. Six types of multistability in a neuronal model based on slow calcium current.

    Directory of Open Access Journals (Sweden)

    Tatiana Malashchenko

    Full Text Available BACKGROUND: Multistability of oscillatory and silent regimes is a ubiquitous phenomenon exhibited by excitable systems such as neurons and cardiac cells. Multistability can play functional roles in short-term memory and maintaining posture. It seems to pose an evolutionary advantage for neurons which are part of multifunctional Central Pattern Generators to possess multistability. The mechanisms supporting multistability of bursting regimes are not well understood or classified. METHODOLOGY/PRINCIPAL FINDINGS: Our study is focused on determining the bio-physical mechanisms underlying different types of co-existence of the oscillatory and silent regimes observed in a neuronal model. We develop a low-dimensional model typifying the dynamics of a single leech heart interneuron. We carry out a bifurcation analysis of the model and show that it possesses six different types of multistability of dynamical regimes. These types are the co-existence of 1 bursting and silence, 2 tonic spiking and silence, 3 tonic spiking and subthreshold oscillations, 4 bursting and subthreshold oscillations, 5 bursting, subthreshold oscillations and silence, and 6 bursting and tonic spiking. These first five types of multistability occur due to the presence of a separating regime that is either a saddle periodic orbit or a saddle equilibrium. We found that the parameter range wherein multistability is observed is limited by the parameter values at which the separating regimes emerge and terminate. CONCLUSIONS: We developed a neuronal model which exhibits a rich variety of different types of multistability. We described a novel mechanism supporting the bistability of bursting and silence. This neuronal model provides a unique opportunity to study the dynamics of networks with neurons possessing different types of multistability.

  19. Calibration of Gurson-type models for porous sheet metals with anisotropic non-quadratic plasticity

    Science.gov (United States)

    Gologanu, M.; Kami, A.; Comsa, D. S.; Banabic, D.

    2016-08-01

    The growth and coalescence of voids in sheet metals are not only the main active mechanisms in the final stages of fracture in a necking band, but they also contribute to the forming limits via changes in the normal directions to the yield surface. A widely accepted method to include void effects is the development of a Gurson-type model for the appropriate yield criterion, based on an approximate limit analysis of a unit cell containing a single spherical, spheroidal or ellipsoidal void. We have recently [2] obtained dissipation functions and Gurson-type models for porous sheet metals with ellipsoidal voids and anisotropic non-quadratic plasticity, including yield criteria based on linear transformations (Yld91 and Yld2004-18p) and a pure plane stress yield criteria (BBC2005). These Gurson-type models contain several parameters that depend on the void and cell geometries and on the selected yield criterion. Best results are obtained when these key parameters are calibrated via numerical simulations using the same unit cell and a few representative loading conditions. The single most important such loading condition corresponds to a pure hydrostatic macroscopic stress (pure pressure) and the corresponding velocity field found during the solution of the limit analysis problem describes the expansion of the cavity. However, for the case of sheet metals, the condition of plane stress precludes macroscopic stresses with large triaxiality or ratio of mean stress to equivalent stress, including the pure hydrostatic case. Also, pure plane stress yield criteria like BBC2005 must first be extended to 3D stresses before attempting to develop a Gurson-type model and such extensions are purely phenomenological with no due account for the out- of-plane anisotropic properties of the sheet. Therefore, we propose a new calibration method for Gurson- type models that uses only boundary conditions compatible with the plane stress requirement. For each such boundary condition we use

  20. Axially Symmetric Bianchi Type-I Bulk-Viscous Cosmological Models with Time-Dependent and

    Indian Academy of Sciences (India)

    Nawsad Ali

    2013-09-01

    The present study deals with spatially homogeneous and anisotropic axially symmetric Bianchi type-I cosmological model with time variable cosmological term in the presence of bulk viscous fluid. The Einstein’s field equations are solved explicitly by time varying deceleration parameter . Consequences of the four cases of phenomenological decay of have been discussed which are consistent with observations. Physical and kinematical parameters of the models are discussed.

  1. Type III Seesaw and Dark Matter in a Supersymmetric Left-Right Model

    CERN Document Server

    Borah, Debasish

    2009-01-01

    We propose a new supersymmetric left right model with Higgs doublets carrying odd B-L charge, higgs bidoublet and heavy Higgs triplets with zero B-L charge and a set of sterile neutrinos which are singlet under the gauge group. We show that spontaneous parity violation can be achieved naturally in this model and the neutrino masses arise from the so called type III seesaw mechanism. We also discuss the possible phenomenology in the context of neutrino masses and dark matter.

  2. Global Analysis of a Delayed Impulsive Lotka-Volterra Model with Holling III Type Functional Response

    Directory of Open Access Journals (Sweden)

    Hui Wang

    2015-01-01

    Full Text Available A delayed impulsive Lotka-Volterra model with Holing III type functional response was established. With the help of Mawhin’s Continuation Theorem in coincidence degree theory, a sufficient condition is found for the existence of positive periodic solutions of the system under consideration. By applying the comparison theorem and constructing a suitable Lyapunov functional, the permanence and global attractivity of the model are proved. Two numerical simulations are also given to illustrate our main results.

  3. An EOQ model with time dependent Weibull deterioration and ramp type demand ,

    Directory of Open Access Journals (Sweden)

    Chaitanya Kumar Tripathy

    2011-04-01

    Full Text Available This paper presents an order level inventory system with time dependent Weibull deterioration and ramp type demand rate where production and demand are time dependent. The proposed model of this paper considers economic order quantity under two different cases. The implementation of the proposed model is illustrated using some numerical examples. Sensitivity analysis is performed to show the effect of changes in the parameters on the optimum solution.

  4. Searching the charged Higgs boson of the type III two Higss doublet model

    CERN Document Server

    Cardenas, H

    2008-01-01

    In the framework of the Two Higgs Doublet Model (2HDM) type III appears two charged Higgs boson and recently there are experimental reports from D0 and CDF collaborations searching a particular signature of new physics. We present a review of the analisys done in the region $M_{H^+}>m_t$ by D0 collaboration and we use the ratio $R_\\sigma$ for the region $M_{H^+} < m_t$ in different scenarios of space parameter of this model.

  5. Multi-Tissue Computational Modeling Analyzes Pathophysiology of Type 2 Diabetes in MKR Mice

    Science.gov (United States)

    Kumar, Amit; Harrelson, Thomas; Lewis, Nathan E.; Gallagher, Emily J.; LeRoith, Derek; Shiloach, Joseph; Betenbaugh, Michael J.

    2014-01-01

    Computational models using metabolic reconstructions for in silico simulation of metabolic disorders such as type 2 diabetes mellitus (T2DM) can provide a better understanding of disease pathophysiology and avoid high experimentation costs. There is a limited amount of computational work, using metabolic reconstructions, performed in this field for the better understanding of T2DM. In this study, a new algorithm for generating tissue-specific metabolic models is presented, along with the resulting multi-confidence level (MCL) multi-tissue model. The effect of T2DM on liver, muscle, and fat in MKR mice was first studied by microarray analysis and subsequently the changes in gene expression of frank T2DM MKR mice versus healthy mice were applied to the multi-tissue model to test the effect. Using the first multi-tissue genome-scale model of all metabolic pathways in T2DM, we found out that branched-chain amino acids' degradation and fatty acids oxidation pathway is downregulated in T2DM MKR mice. Microarray data showed low expression of genes in MKR mice versus healthy mice in the degradation of branched-chain amino acids and fatty-acid oxidation pathways. In addition, the flux balance analysis using the MCL multi-tissue model showed that the degradation pathways of branched-chain amino acid and fatty acid oxidation were significantly downregulated in MKR mice versus healthy mice. Validation of the model was performed using data derived from the literature regarding T2DM. Microarray data was used in conjunction with the model to predict fluxes of various other metabolic pathways in the T2DM mouse model and alterations in a number of pathways were detected. The Type 2 Diabetes MCL multi-tissue model may explain the high level of branched-chain amino acids and free fatty acids in plasma of Type 2 Diabetic subjects from a metabolic fluxes perspective. PMID:25029527

  6. Multi-tissue computational modeling analyzes pathophysiology of type 2 diabetes in MKR mice.

    Directory of Open Access Journals (Sweden)

    Amit Kumar

    Full Text Available Computational models using metabolic reconstructions for in silico simulation of metabolic disorders such as type 2 diabetes mellitus (T2DM can provide a better understanding of disease pathophysiology and avoid high experimentation costs. There is a limited amount of computational work, using metabolic reconstructions, performed in this field for the better understanding of T2DM. In this study, a new algorithm for generating tissue-specific metabolic models is presented, along with the resulting multi-confidence level (MCL multi-tissue model. The effect of T2DM on liver, muscle, and fat in MKR mice was first studied by microarray analysis and subsequently the changes in gene expression of frank T2DM MKR mice versus healthy mice were applied to the multi-tissue model to test the effect. Using the first multi-tissue genome-scale model of all metabolic pathways in T2DM, we found out that branched-chain amino acids' degradation and fatty acids oxidation pathway is downregulated in T2DM MKR mice. Microarray data showed low expression of genes in MKR mice versus healthy mice in the degradation of branched-chain amino acids and fatty-acid oxidation pathways. In addition, the flux balance analysis using the MCL multi-tissue model showed that the degradation pathways of branched-chain amino acid and fatty acid oxidation were significantly downregulated in MKR mice versus healthy mice. Validation of the model was performed using data derived from the literature regarding T2DM. Microarray data was used in conjunction with the model to predict fluxes of various other metabolic pathways in the T2DM mouse model and alterations in a number of pathways were detected. The Type 2 Diabetes MCL multi-tissue model may explain the high level of branched-chain amino acids and free fatty acids in plasma of Type 2 Diabetic subjects from a metabolic fluxes perspective.

  7. A Based-Bottleneck Multiple Vehicle Type Dynamic Marginal Cost Model and Algorithm

    Directory of Open Access Journals (Sweden)

    Shuguang Li

    2012-09-01

    Full Text Available Single vehicle type dynamic marginal cost model is extended to multiple vehicle type dynamic one based on time-dependent multiple vehicle type queue analysis at a bottleneck. A dynamic link model is presented to model interactions between cars and trucks, given the link consists of two distinct segments. The first segment is the running segment on which cars (trucks run at their free-flow speeds and the second segment is the exit queue segment. A car or a truck is assumed to be a point without length. The class-specific pi parameter is used to transform the effect of truck into passenger car equivalents, so the exit flow of cars and trucks can be calculated according to the exit capacity of a bottleneck. The analytic expression of multiple vehicle type dynamic marginal cost function is deduced under congested and uncongested conditions. Then a heuristic algorithm is presented in solving multiple vehicle type dynamic queues, tolls under system optimum and user equilibrium conditions. The numerical example illustrates the simplicity and applicability of the proposed approach.

  8. A host-parasite model for a two-type cell population

    CERN Document Server

    Alsmeyer, Gerold

    2012-01-01

    A host-parasite model is considered for a population of cells that can be of two types, A or B, and exhibits unilateral reproduction: while a B-cell always splits into two cells of the same type, the two daughter cells of an A-cell can be of any type. The random mechanism that describes how parasites within a cell multiply and are then shared into the daughter cells is allowed to depend on the hosting mother cell as well as its daughter cells. Focusing on the subpopulation of A-cells and its parasites, the model differs from the single-type model recently studied by Bansaye (2008) in that the sharing mechanism may be biased towards one of the two types. Main results are concerned with the nonextinctive case and provide information on the behavior, as $n\\to\\infty$, of the number A-parasites in generation n and the relative proportion of A- and B-cells in this generation which host a given number of parasites. As in (Bansaye,2008), proofs will make use of a so-called random cell line which, when conditioned to ...

  9. Small-animal PET imaging of the type 1 and type 2 cannabinoid receptors in a photothrombotic stroke model

    Energy Technology Data Exchange (ETDEWEB)

    Vandeputte, Caroline; Casteels, Cindy; Koole, Michel; Gerits, Anneleen [KU Leuven, Division of Nuclear Medicine, Leuven (Belgium); KU Leuven, Molecular Small Animal Imaging Center, MoSAIC, Leuven (Belgium); Struys, Tom [Hasselt University, Laboratory of Histology, Biomedical Research Institute, Hasselt (Belgium); KU Leuven, Biomedical NMR Unit, Leuven (Belgium); Veghel, Daisy van; Evens, Nele; Bormans, Guy [KU Leuven, Molecular Small Animal Imaging Center, MoSAIC, Leuven (Belgium); KU Leuven, Laboratory of Radiopharmacy, Leuven (Belgium); Dresselaers, Tom; Himmelreich, Uwe [KU Leuven, Molecular Small Animal Imaging Center, MoSAIC, Leuven (Belgium); KU Leuven, Biomedical NMR Unit, Leuven (Belgium); Lambrichts, Ivo [Hasselt University, Laboratory of Histology, Biomedical Research Institute, Hasselt (Belgium); Laere, Koen van [KU Leuven, Division of Nuclear Medicine, Leuven (Belgium); KU Leuven, Molecular Small Animal Imaging Center, MoSAIC, Leuven (Belgium); UZ Leuven, Division of Nuclear Medicine, Leuven (Belgium)

    2012-11-15

    Recent ex vivo and pharmacological evidence suggests involvement of the endocannabinoid system in the pathophysiology of stroke, but conflicting roles for type 1 and 2 cannabinoid receptors (CB{sub 1} and CB{sub 2}) have been suggested. The purpose of this study was to evaluate CB{sub 1} and CB{sub 2} receptor binding over time in vivo in a rat photothrombotic stroke model using PET. CB{sub 1} and CB{sub 2} microPET imaging was performed at regular time-points up to 2 weeks after stroke using [{sup 18}F]MK-9470 and [{sup 11}C]NE40. Stroke size was measured using MRI at 9.4 T. Ex vivo validation was performed via immunostaining for CB{sub 1} and CB{sub 2}. Immunofluorescent double stainings were also performed with markers for astrocytes (GFAP) and macrophages/microglia (CD68). [{sup 18}F]MK-9470 PET showed a strong increase in CB{sub 1} binding 24 h and 72 h after stroke in the cortex surrounding the lesion, extending to the insular cortex 24 h after surgery. These alterations were consistently confirmed by CB{sub 1} immunohistochemical staining. [{sup 11}C]NE40 did not show any significant differences between stroke and sham-operated animals, although staining for CB{sub 2} revealed minor immunoreactivity at 1 and 2 weeks after stroke in this model. Both CB{sub 1} {sup +} and CB{sub 2} {sup +} cells showed minor immunoreactivity for CD68. Time-dependent and regionally strongly increased CB{sub 1}, but not CB{sub 2}, binding are early consequences of photothrombotic stroke. Pharmacological interventions should primarily aim at CB{sub 1} signalling as the role of CB{sub 2} seems minor in the acute and subacute phases of stroke. (orig.)

  10. Bianchi Type VI1 Viscous Fluid Cosmological Model in Wesson´s Theory of Gravitation

    Science.gov (United States)

    Khadekar, G. S.; Avachar, G. R.

    2007-03-01

    Field equations of a scale invariant theory of gravitation proposed by Wesson [1, 2] are obtained in the presence of viscous fluid with the aid of Bianchi type VIh space-time with the time dependent gauge function (Dirac gauge). It is found that Bianchi type VIh (h = 1) space-time with viscous fluid is feasible in this theory, whereas Bianchi type VIh (h = -1, 0) space-times are not feasible in this theory, even in the presence of viscosity. For the feasible case, by assuming a relation connecting viscosity and metric coefficient, we have obtained a nonsingular-radiating model. We have discussed some physical and kinematical properties of the models.

  11. A semi-analytical light curve model and its application to type IIP supernovae

    CERN Document Server

    Nagy, Andrea P; Vinko, Jozsef; Wheeler, J Craig

    2014-01-01

    The aim of this work is to present a semi-analytical light curve modeling code which can be used for estimating physical properties of core collapse supernovae (SNe) in a quick and efficient way. To verify our code we fit light curves of Type II SNe and compare our best parameter estimates to those from hydrodynamical calculations. For this analysis we use the quasi-bolometric light curves of five different Type IIP supernovae. In each case we get appropriate results for the initial pre-supernova parameters. We conclude that this semi-analytical light curve model is useful to get approximate physical properties of Type II SNe without using time-consuming numerical hydrodynamic simulations.

  12. Forward Modeling of Different Types of Landslides with Multi-electrode Electric Method

    Institute of Scientific and Technical Information of China (English)

    GuoXiujun; HuangXiaoyu; JiaYonggang

    2005-01-01

    Multi-electrode Electric Method (MEM) is an effective tool in landslide survey. A suitable working scheme in-situ and the corresponding data interpretation approach are the fundamentals for obtaining believable results. Finite element 2D forward modeling was conducted on four types of standard electric models; respectively named the homogeneous soil landside, bedding landside, sliderock landside, and beveling landside; under the utilizations of four different types of electrode arrays;respectively namely the Wenner array, Schlumberger array, dipole-dipole array and pole-pole array.The capacities of different arrays and the resistivity responses of different types of sliding faces were determined based on the resultant standard electric profiles. An innovative data processing procedure called the ratio parameter method was proposed for locating sliding faces under complex geological conditions. A series of case histories for landside survey were given.

  13. Z-type control of populations for Lotka-Volterra model with exponential convergence.

    Science.gov (United States)

    Zhang, Yunong; Yan, Xiaogang; Liao, Bolin; Zhang, Yinyan; Ding, Yaqiong

    2016-02-01

    The population control of the Lotka-Volterra model is one of the most important and widely investigated issues in mathematical ecology. In this study, assuming that birth rate is controllable and using the Z-type dynamic method, we develop Z-type control laws to drive the prey population and/or predator population to a desired state to keep species away from extinction and to improve ecosystem stability. A direct controller group is initially designed to control the prey and predator populations simultaneously. Two indirect controllers are then proposed for prey population control and predator population control by exerting exogenous measure on another species. All three control laws possess exponential convergence performances. Finally, the corresponding numerical simulations are performed. Results substantiate the theoretical analysis and effectiveness of such Z-type control laws for the population control of the Lotka-Volterra model. Copyright © 2015 Elsevier Inc. All rights reserved.

  14. Attitudinal Effects of the Use of Role Models in Information about Sex-Typed Careers.

    Science.gov (United States)

    Green, Andrea Lupo; And Others

    1982-01-01

    In rating the appropriateness of nontraditional jobs for men and women, indications are that students' attitudes can be changed by exposure to nontraditional models. The study of written job descriptions which were rated by students analyzes male and female sex-typed attitudes and beliefs about appropriateness of gender to career. (CM)

  15. Design, Modeling and Control of Magnetic Bearings for a Ring-Type Flywheel Energy Storage System

    Directory of Open Access Journals (Sweden)

    Chow-Shing Toh

    2016-12-01

    Full Text Available This study is concerned with the magnetic force models of magnetic bearing in a flywheel energy storage system (FESS. The magnetic bearing is of hybrid type, with axial passive magnetic bearing (PMB and radial hybrid magnetic bearing (HMB. For the PMB, a pair of ring-type Halbach arrays of permanent magnets are arranged vertically to support the rotor weight. For the HMB, a set of ring-type Halbach array is placed on the rotor side, which corresponds to coil sets on the stator side. The HMB can produce both attraction and repulsion forces on the radial direction, depending on the direction of the coil currents. It is found that the ring-type configuration and the differential winding scheme for coil sets can yield linear magnetic force models for both PMB and HMB. Based on the obtained magnetic force model, an integral sliding mode controller is designed for the stable rotor levitation in the radial direction. The experimental results show that the rotor can be stabilized to the bearing center, verifying the accuracy of the magnetic force models and effectiveness of the levitation controller.

  16. Modelling of horn-type loudspeakers for outdoor sound reinforcement systems

    DEFF Research Database (Denmark)

    Schuhmacher, Andreas; Rasmussen, Karsten Bo

    1999-01-01

    -type loudspeakers is made. The agreement between measured and calculated results is very good provided that a sufficient number of modes is included in the simulation. Simulation models of this kind represent one of the first steps towards a CAD tool for outdoor sound reinforcement systems....

  17. Social Ecological Model of Illness Management in High-Risk Youths with Type 1 Diabetes

    Science.gov (United States)

    Naar-King, Sylvie; Podolski, Cheryl-Lynn; Ellis, Deborah A.; Frey, Maureen A.; Templin, Thomas

    2006-01-01

    In this study, the authors tested a social ecological model of illness management in high-risk, urban adolescents with Type 1 diabetes. It was hypothesized that management behaviors would be associated with individual adolescent characteristics as well as family, peer, and provider relationships. Questionnaires were collected from 96 adolescents…

  18. Method of renormalization potential for one model of Hartree-Fock-Slater type

    CERN Document Server

    Zasorin, Y V

    2002-01-01

    A new method of the potential renormalization for the quasiclassical model of the Hartree-Fock-Slater real potential is proposed. The method makes it possible to easily construct the wave functions and contrary to the majority od similar methods it does not require the knowledge of the real-type potential

  19. Predicting major outcomes in type 1 diabetes: a model development and validation study

    NARCIS (Netherlands)

    Soedamah-Muthu, S.S.; Vergouwe, Y.; Costacou, T.; Miller, R.G.; Zgibor, J.; Chaturvedi, N.; Snell-Bergeon, J.K.; Maahs, D.M.; Rewers, M.; Forsblom, C.; Harjutsalo, V.; Groop, P.H.; Fuller, J.H.; Moons, K.G.M.; Orchard, T.J.

    2014-01-01

    Aims/hypothesis Type 1 diabetes is associated with a higher risk of major vascular complications and death. A reliable method that predicted these outcomes early in the disease process would help in risk classification. We therefore developed such a prognostic model and quantified its performance in

  20. 40 CFR 600.207-93 - Calculation of fuel economy values for a model type.

    Science.gov (United States)

    2010-07-01

    ... base level. (7) For alcohol dual fuel automobiles and natural gas dual fuel automobiles the procedures... combined fuel economy values from the tests performed using gasoline or diesel test fuel. (ii) Calculate... economy values for the model type. (5) For alcohol dual fuel automobiles and natural gas dual fuel...

  1. Phase structure, critical points and susceptibilities in Nambu-Jona-Lasinio type models

    CERN Document Server

    De Sousa, C A; Ruivo, M C

    2008-01-01

    We investigate the chiral phase transition at finite temperature and chemical potential within SU(2) and SU(3) Nambu-Jona-Lasinio type models. The behavior of the baryon number susceptibility and the specific heat, in the vicinity of the critical end point, is studied. The class of the critical points is analyzed by calculating critical exponents.

  2. Novel lean type 2 diabetic rat model using gestational low-protein programming

    Science.gov (United States)

    Type 2 diabetes (T2D) in lean individuals is not well studied and up to 26% of diabetes occurs in these individuals. Although the cause is not well understood, it has been primarily attributed to nutritional issues during early development. Our objective was to develop a lean T2D model using gestati...

  3. A mathematical model of amphibian skin epithelium with two types of transporting cellular units

    DEFF Research Database (Denmark)

    Larsen, Erik Hviid; Rasmussen, B E

    1985-01-01

    A computer model of ion transport across amphibian skin epithelium containing two types of cellular units, their relative number and sizes, and a paracellular pathway has been developed. The two cellular units are, a large Na+ transporting compartment representing the major epithelium from stratum...

  4. Craniofacial Statistical Deformation Models of Wild-type mice and Crouzon mice

    DEFF Research Database (Denmark)

    Ólafsdóttir, Hildur; Darvann, Tron Andre; Ersbøll, Bjarne Kjær

    2007-01-01

    of Micro CT scannings of the heads of wild-type (normal) mice and Crouzon mice were investigated. Statistical deformation models were built to assess the anatomical differences between the groups, as well as the within-group anatomical variation. Following the approach by Rueckert et al. we built an atlas...

  5. MODELS OF EVALUATION OF TEST TASKS OF DIFFERENT TYPES AND DETERMINATION OF THEIR LEVEL OF COMLICATION

    Directory of Open Access Journals (Sweden)

    V. P. Martsenyuk

    2012-11-01

    Full Text Available The paper is devoted to the test items marking technology and distribution of different types items by the levels of complication. At distribution of test items on complication levels it is offered to use the integrated functional model which allows to apply different ways of the test items distribution included in the test.

  6. Models of Parenting: Implications for Adolescent Well-Being within Different Types of Family Contexts.

    Science.gov (United States)

    Shucksmith, J.; And Others

    1995-01-01

    Examines parenting models and parent-child relationships from early to middle adolescence. Focuses on implications for adolescent functioning, including school integration and psychological well being. Results identify four distinct types of parenting styles characterized by different degrees of acceptance and control of young people's behavior.…

  7. Van der Waals Type Model for Neutron-Proton Elastic Scattering at High Energies

    Science.gov (United States)

    Aleem, F.

    1980-12-01

    The most recent measurements of the angular distribution and total cross-section for neutron-proton elastic scattering between 70< pL <400 GeV/c with squared four momentum transfer -t ≤ 3.6 (GeV/c)2 have been explained using Van der Waals type model.

  8. Future Asymptotic Behaviour of Tilted Bianchi models of type IV and VIIh

    CERN Document Server

    Hervik, S; Coley, Alan A; Hervik, Sigbjorn; Hoogen, Robert van den; Coley, Alan

    2005-01-01

    Using dynamical systems theory and a detailed numerical analysis, the late-time behaviour of tilting perfect fluid Bianchi models of types IV and VII$_h$ are investigated. In particular, vacuum plane-wave spacetimes are studied and the important result that the only future attracting equilibrium points for non-inflationary fluids are the plane-wave solutions in Bianchi type VII$_h$ models is discussed. A tiny region of parameter space (the loophole) in the Bianchi type IV model is shown to contain a closed orbit which is found to act as an attractor (the Mussel attractor). From an extensive numerical analysis it is found that at late times the normalised energy-density tends to zero and the normalised variables 'freeze' into their asymptotic values. A detailed numerical analysis of the type VII$_h$ models then shows that there is an open set of parameter space in which solution curves approach a compact surface that is topologically a torus.

  9. Bianchi Type-Ⅲ String Cosmological Model with Bulk Viscosity in General Relativity

    Institute of Scientific and Technical Information of China (English)

    WANG Xing-Xiang

    2005-01-01

    The Bianchi type-Ⅲcosmological model for a cloud string with bulk viscosity are studied. To obtain a determinate solution, it is assumed that the coefficient of bulk viscosity is a power function of the scalar of expansion ζ = kθm and the shear scalar is proportional to scalar of expansion σ∝θ, which leads to the relation between metric potentials B = Cn. The physical features of the model are also discussed. It is found that the power index mhas significant influence on the string model. There is a "big bang" start in the model when m ≤ 1 but there is no the big-bang start when m > 1. In the special case m = 0, the model reduces to the string model of constant coefficient of bulk viscosity that was the result previously given in the literature.

  10. Comparison between sparsely distributed memory and Hopfield-type neural network models

    Science.gov (United States)

    Keeler, James D.

    1986-01-01

    The Sparsely Distributed Memory (SDM) model (Kanerva, 1984) is compared to Hopfield-type neural-network models. A mathematical framework for comparing the two is developed, and the capacity of each model is investigated. The capacity of the SDM can be increased independently of the dimension of the stored vectors, whereas the Hopfield capacity is limited to a fraction of this dimension. However, the total number of stored bits per matrix element is the same in the two models, as well as for extended models with higher order interactions. The models are also compared in their ability to store sequences of patterns. The SDM is extended to include time delays so that contextual information can be used to cover sequences. Finally, it is shown how a generalization of the SDM allows storage of correlated input pattern vectors.

  11. Impulsive Control on Seasonally Perturbed General Holling Type Two-Prey One-Predator Model

    Directory of Open Access Journals (Sweden)

    Chandrima Banerjee

    2016-01-01

    Full Text Available We investigate the dynamical behaviors of two-prey one-predator model with general Holling type functional responses. The effect of seasonal perturbation on the model has been discussed analytically as well as numerically. The periodic fluctuation is considered in prey growth rate and the predator mortality rate of the model. The impulsive effects involving biological and chemical control strategy, periodic releasing of natural enemies, and spraying pesticide at different fixed times are introduced in the model with seasonal perturbation. We derive the conditions of stability for impulsive system using Floquet theory, small amplitude perturbation skills. A local asymptotically stable prey (pest eradicated periodic solution is obtained when the impulsive period is less than some critical value. Numerical simulations of the model with and without seasonal disturbances exhibit different dynamics. Also we simulate numerically the model involving seasonal perturbations without impulse and with impulse. Finally, concluding remarks are given.

  12. Thermodynamics and dynamical properties of the KH2PO4 type ferroelectric compounds. A unified model

    Directory of Open Access Journals (Sweden)

    R.R. Levitskii

    2009-01-01

    Full Text Available Within the framework of the proposed unified proton ordering model for the ferroelectric compounds of the KH2PO4 family, in the four-particle cluster approximation for the short-range interactions and mean field approximation for the long-range interactions, we calculate thermodynamic and longitudinal dynamic characteristics of the KD2PO4 type ferroelectrics and ND4D2PO4 type antiferroelectrics. Calculations for partially deuterated K(H1-xDx2PO4 type ferroelectrics and N(H1-xDx4(H1-xDx2PO4 type antiferroelectrics are performed within the mean crystal approximation. It is shown that at the proper choice of the theory parameters, a good quantitative description of experimental data for the KH2PO4 family crystals is obtained.

  13. On Compound Poisson Processes Arising in Change-Point Type Statistical Models as Limiting Likelihood Ratios

    CERN Document Server

    Dachian, Serguei

    2010-01-01

    Different change-point type models encountered in statistical inference for stochastic processes give rise to different limiting likelihood ratio processes. In a previous paper of one of the authors it was established that one of these likelihood ratios, which is an exponential functional of a two-sided Poisson process driven by some parameter, can be approximated (for sufficiently small values of the parameter) by another one, which is an exponential functional of a two-sided Brownian motion. In this paper we consider yet another likelihood ratio, which is the exponent of a two-sided compound Poisson process driven by some parameter. We establish, that similarly to the Poisson type one, the compound Poisson type likelihood ratio can be approximated by the Brownian type one for sufficiently small values of the parameter. We equally discuss the asymptotics for large values of the parameter and illustrate the results by numerical simulations.

  14. A Hybrid Model for Individual Identification Based on Keystroke Data in Japanese Free Text Typing

    Science.gov (United States)

    Samura, Toshiharu; Nishimura, Haruhiko

    We have investigated several characteristics of keystroke dynamics in Japanese free text typing. We performed experiments on 189 subjects, representing three groups according to the number of letters they could type in five minutes. In this experiment, we extracted the feature indices from the keystroke timing for each alphabet single letter and for two-letter combinations composed of consonant and vowel pairs in Japanese text. Taking into account two identification methods using weighted Euclidean distance (WED) and Vector Disorder (VD), we proposed their hybrid model for individual identification based on keystroke data in Japanese free text typing. By evaluating the personal identification for the three groups, its high performance was confirmed in proportion to the typing level of the group.

  15. Type-specific human papillomavirus biological features: validated model-based estimates.

    Directory of Open Access Journals (Sweden)

    Iacopo Baussano

    Full Text Available Infection with high-risk (hr human papillomavirus (HPV is considered the necessary cause of cervical cancer. Vaccination against HPV16 and 18 types, which are responsible of about 75% of cervical cancer worldwide, is expected to have a major global impact on cervical cancer occurrence. Valid estimates of the parameters that regulate the natural history of hrHPV infections are crucial to draw reliable projections of the impact of vaccination. We devised a mathematical model to estimate the probability of infection transmission, the rate of clearance, and the patterns of immune response following the clearance of infection of 13 hrHPV types. To test the validity of our estimates, we fitted the same transmission model to two large independent datasets from Italy and Sweden and assessed finding consistency. The two populations, both unvaccinated, differed substantially by sexual behaviour, age distribution, and study setting (screening for cervical cancer or Chlamydia trachomatis infection. Estimated transmission probability of hrHPV types (80% for HPV16, 73%-82% for HPV18, and above 50% for most other types; clearance rates decreasing as a function of time since infection; and partial protection against re-infection with the same hrHPV type (approximately 20% for HPV16 and 50% for the other types were similar in the two countries. The model could accurately predict the HPV16 prevalence observed in Italy among women who were not infected three years before. In conclusion, our models inform on biological parameters that cannot at the moment be measured directly from any empirical data but are essential to forecast the impact of HPV vaccination programmes.

  16. Validation of a model of family caregiver communication types and related caregiver outcomes.

    Science.gov (United States)

    Wittenberg, Elaine; Kravits, Kate; Goldsmith, Joy; Ferrell, Betty; Fujinami, Rebecca

    2017-02-01

    Caring for the family is included as one of the eight domains of quality palliative care, calling attention to the importance of the family system and family communications about cancer during care and treatment of the disease. Previously, a model of family caregiver communication defined four caregiver communication types-Manager, Carrier, Partner, Lone-each with a unique communication pattern. The purpose of the present study was to extend the model of family caregiver communication in cancer care to further understand the impact of family communication burden on caregiving outcomes. This mixed-method study employed fieldnotes from a family caregiver intervention focused on quality of life and self-reported caregiver communication items to identify a specific family caregiver type. Caregiver types were then analyzed using outcome measures on psychological distress, skills preparedness, family inventory of needs, and quality-of-life domains. Corroboration between fieldnotes and self-reported communication for caregivers (n = 21, 16 women, mean age of 53 years) revealed a definitive classification of the four caregiver types (Manager = 6, Carrier = 5, Partner = 6, Lone = 4). Mean scores on self-reported communication items documented different communication patterns congruent with the theoretical framework of the model. Variation in caregiver outcomes measures confirmed the model of family caregiver communication types. Partner and Lone caregivers reported the lowest psychological distress, with Carrier caregivers feeling least prepared and Manager caregivers reporting the lowest physical quality of life. This study illustrates the impact of family communication on caregiving and increases our knowledge and understanding about the role of communication in caregiver burden. The research provides the first evidence-based validation for a family caregiver communication typology and its relationship to caregiver outcomes. Future research is needed to develop and test

  17. Climate stability for a Sellers-type model. [atmospheric diffusive energy balance model

    Science.gov (United States)

    Ghil, M.

    1976-01-01

    We study a diffusive energy-balance climate model governed by a nonlinear parabolic partial differential equation. Three positive steady-state solutions of this equation are found; they correspond to three possible climates of our planet: an interglacial (nearly identical to the present climate), a glacial, and a completely ice-covered earth. We consider also models similar to the main one studied, and determine the number of their steady states. All the models have albedo continuously varying with latitude and temperature, and entirely diffusive horizontal heat transfer. The diffusion is taken to be nonlinear as well as linear. We investigate the stability under small perturbations of the main model's climates. A stability criterion is derived, and its application shows that the 'present climate' and the 'deep freeze' are stable, whereas the model's glacial is unstable. A variational principle is introduced to confirm the results of this stability analysis. For a sufficient decrease in solar radiation (about 2%) the glacial and interglacial solutions disappear, leaving the ice-covered earth as the only possible climate.

  18. Nominal Henkin Semantics: simply-typed lambda-calculus models in nominal sets

    CERN Document Server

    Gabbay, Murdoch J; 10.4204/EPTCS.71.5

    2011-01-01

    We investigate a class of nominal algebraic Henkin-style models for the simply typed lambda-calculus in which variables map to names in the denotation and lambda-abstraction maps to a (non-functional) name-abstraction operation. The resulting denotations are smaller and better-behaved, in ways we make precise, than functional valuation-based models. Using these new models, we then develop a generalisation of \\lambda-term syntax enriching them with existential meta-variables, thus yielding a theory of incomplete functions. This incompleteness is orthogonal to the usual notion of incompleteness given by function abstraction and application, and corresponds to holes and incomplete objects.

  19. Study of Bianchi type-I model in f(R,Tψ) gravity

    Science.gov (United States)

    Sharif, M.; Siddiqa, Aisha

    2017-03-01

    We study the cosmological behavior of locally rotationally symmetric (LRS) Bianchi type-I universe model in f (R ,Tψ) gravity. For this purpose, we evaluate Hubble parameter, effective equation of state parameter (ωeff) and potential of scalar field (ψ) as a function of time using the assumption H = W (ψ). The behavior of these parameters is investigated for different models of W (ψ). It is concluded that exponential form of W (ψ) leads to time independent ωeff which corresponds to different stages of evolution while for the other two models, they correspond to stiff fluid stage.

  20. Correlation of h→γγ and Zγ in Type-II seesaw neutrino model

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Chian-Shu, E-mail: chianshu@phys.sinica.edu.tw [Department of Physics, National Tsing Hua University, Hsinchu, Taiwan (China); Physics Division, National Center for Theoretical Sciences, Hsinchu, Taiwan (China); Geng, Chao-Qiang, E-mail: geng@phys.nthu.edu.tw [Department of Physics, National Tsing Hua University, Hsinchu, Taiwan (China); Physics Division, National Center for Theoretical Sciences, Hsinchu, Taiwan (China); Huang, Da, E-mail: dahuang@phys.nthu.edu.tw [Department of Physics, National Tsing Hua University, Hsinchu, Taiwan (China); Tsai, Lu-Hsing, E-mail: lhtsai@phys.nthu.edu.tw [Department of Physics, National Tsing Hua University, Hsinchu, Taiwan (China)

    2013-06-10

    We study the charged scalar contributions to the Higgs decay channels of h→γγ and h→Zγ in the Type-II seesaw neutrino model. In most of the allowed parameter space in the model, the new contribution to h→Zγ is positively correlated with that to h→γγ. If the current excess of the h→γγ rate measured by the ATLAS Collaboration persists, the h→Zγ rate should be also larger than the corresponding standard model prediction. We demonstrate that the anti-correlation between h→γγ and h→Zγ only exists in some special region.

  1. Modeling, Simulation and Control of a Redundant SCARA-Type Manipulator Robot

    Directory of Open Access Journals (Sweden)

    Claudio Urrea

    2012-08-01

    Full Text Available In this paper, the modeling of a redundant SCARA‐type manipulator robot with five degrees of freedom is presented. We propose three controllers ‐ hyperbolic sine‐cosine, sliding mode, and calculated torque ‐ which are applied to the discussed model. A simulation environment is developed using MatLab/Simulink programming tools. This simulation environment is employed to perform several tests (including actuatorsʹ dynamics on the model of the redundant manipulator, with each different controller, under path tracking requirements. Results were obtained from comparative curves and rms index for joints and Cartesian errors.

  2. Modelling of the Residual Stress State in a new Type of Residual Stress Specimen

    DEFF Research Database (Denmark)

    Jakobsen, Johnny; Andreasen, Jens Henrik

    2014-01-01

    The paper presents a study on a new type residual stress specimen which is proposed as a simple way to conduct experimental validation for model predictions. A specimen comprising of a steel plate with circular hole embedded into a stack of CSM glass fibre and further infused with an epoxy resin...... forms the experimental case which is analysed. A FE model of the specimen is used for analysing the curing history and the residual stress build up. The model is validated against experimental strain data which are recorded by a Fibre Brag Grating sensor and good agreement has been achieved....

  3. Bianchi Type-Ⅰ Massive String Magnetized Barotropic Perfect Fluid Cosmological Model in General Relativity

    Institute of Scientific and Technical Information of China (English)

    BALI Raj; PAREEK Umesh Kumar; PRADHAN Anirudh

    2007-01-01

    @@ Bianchi type-Ⅰ massive string cosmological model with magnetic field of barotropic perfect fluid distribution through the techniques used by Latelier and Stachel is investigated. To obtain the deterministic model of the universe, it is assumed that the universe is filled with barotropic perfect fluid distribution. The magnetic field is due to electric current produced along the x-axis with infinite electrical condúctivity. The behaviour of the model in the presence and absence of magnetic field together with other physical aspects is further discussed.

  4. Two-warehouse inventory model with ramp-type demand and partially backlogged shortages

    Science.gov (United States)

    Agrawal, Swati; Banerjee, Snigdha

    2011-07-01

    In this article, we consider an inventory model for items that are stored in two-warehouses when demand is a general ramp-type function of time. Shortages are allowed and a constant fraction of shortages is backlogged. The existence and uniqueness of optimal solution is proved for both - the single-warehouse and the two-warehouse models. An algorithm is developed to facilitate the choice between the two-warehouse and the single-warehouse systems and hence to obtain the optimal replenishment policy. Numerical examples are presented. Sensitivity analysis with respect to the parameters of the model is performed.

  5. IS WHITE-COLLAR CRIMINALITY CLOSER TO THE RATIONAL MODEL THAN ANY OTHER TYPE MODEL?

    Directory of Open Access Journals (Sweden)

    Jacob RUB

    2016-03-01

    Full Text Available The basic premise is that white-collar felons are making non-rational decisions. To our opinion, they are not making decisions according to a calculation of profit or loss from perpetration of a crime as it was stated earlier in the scientific literature. In relation to the above mentioned premises, an illegal behavior is an occasion of a white-collar felon deciding to take the law into his own hands while taking risks. Naturally, the level of values and personality of the felon constitute a significant factor. Our current study offers an examination of deterring through a prism of the white-collar felon, who makes the decision to perpetrate a crime according to irrational components as well.White-collar crime, as family violence, and other socially harmful behaviors, is often excluded from examination. Of our opinion all the rational, social, biological, etc. theories of crimes, are the base of the reasons to make an offence, but in reality, the implementation of white-collar criminality closer to the non-rational model than any other type model. People are seen as less than fully rational. Often they do not make decisions that would appear to be in their own best interest for a variety of reasons. First, people do not always have all of the information they need to make informed decisions, and even if they do, may not have the capacity to optimally process that information. The personalities, experiences and options that of human beings given the choice in life, that it is quite naive to assume that we will all assess the situation similarly and arrive at similar choices. Many criminal events appear not to be very rational choices at all, or at least reflect patterns of decision making quite different from those more typically seen among law-abiding citizens. Ближе ли беловоротничковая преступность к рациональной модели, нежели к другим типам моделе

  6. Predicting polarization signatures for double-detonation and delayed-detonation models of Type Ia supernovae

    CERN Document Server

    Bulla, M; Kromer, M; Seitenzahl, I R; Fink, M; Ciaraldi-Schoolmann, F; Roepke, F K; Hillebrandt, W; Pakmor, R; Ruiter, A J; Taubenberger, S

    2016-01-01

    Calculations of synthetic spectropolarimetry are one means to test multi-dimensional explosion models for Type Ia supernovae. In a recent paper, we demonstrated that the violent merger of a 1.1 and 0.9 M$_{\\odot}$ white dwarf binary system is too asymmetric to explain the low polarization levels commonly observed in normal Type Ia supernovae. Here, we present polarization simulations for two alternative scenarios: the sub-Chandrasekhar mass double-detonation and the Chandrasekhar mass delayed-detonation model. Specifically, we study a two-dimensional double-detonation model and a three-dimensional delayed-detonation model, and calculate polarization spectra for multiple observer orientations in both cases. We find modest polarization levels ($<$ 1 per cent) for both explosion models. Polarization in the continuum peaks at $\\sim$ 0.1$-$0.3 per cent and decreases after maximum light, in excellent agreement with spectropolarimetric data of normal Type Ia supernovae. Higher degrees of polarization are found ac...

  7. A kinetic model for type I and II IP3R accounting for mode changes.

    Science.gov (United States)

    Siekmann, Ivo; Wagner, Larry E; Yule, David; Crampin, Edmund J; Sneyd, James

    2012-08-22

    Based upon an extensive single-channel data set, a Markov model for types I and II inositol trisphosphate receptors (IP(3)R) is developed. The model aims to represent accurately the kinetics of both receptor types of IP(3)R depending on the concentrations of inositol trisphosphate (IP(3)), adenosine trisphosphate (ATP), and intracellular calcium (Ca(2+)). In particular, the model takes into account that for some combinations of ligands the IP(3)R switches between extended periods of inactivity alternating with intervals of bursting activity (mode changes). In a first step, the inactive and active modes are modeled separately. It is found that, within modes, both receptor types are ligand-independent. In a second step, the submodels are connected by transition rates. Ligand-dependent regulation of the channel activity is achieved by modulating these transitions between active and inactive modes. As a result, a compact representation of the IP(3)R is obtained that accurately captures stochastic single-channel dynamics including mode changes in a model with six states and 10 rate constants, only two of which are ligand-dependent.

  8. Thermodynamics of spin chains of Haldane-Shastry type and one-dimensional vertex models

    Energy Technology Data Exchange (ETDEWEB)

    Enciso, Alberto [Instituto de Ciencias Matematicas, Consejo Superior de Investigaciones Cientificas, 28049 Madrid (Spain); Finkel, Federico [Departamento de Fisica Teorica II, Universidad Complutense de Madrid, 28040 Madrid (Spain); Gonzalez-Lopez, Artemio, E-mail: artemio@fis.ucm.es [Departamento de Fisica Teorica II, Universidad Complutense de Madrid, 28040 Madrid (Spain)

    2012-11-15

    We study the thermodynamic properties of spin chains of Haldane-Shastry type associated with the A{sub N-1} root system in the presence of a uniform external magnetic field. To this end, we exactly compute the partition function of these models for an arbitrary finite number of spins. We then show that these chains are equivalent to a suitable inhomogeneous classical Ising model in a spatially dependent magnetic field, generalizing the results of Basu-Mallick et al. for the zero magnetic field case. Using the standard transfer matrix approach, we are able to compute in closed form the free energy per site in the thermodynamic limit. We perform a detailed analysis of the chains' thermodynamics in a unified way, with special emphasis on the zero field and zero temperature limits. Finally, we provide a novel interpretation of the thermodynamic quantities of spin chains of Haldane-Shastry type as weighted averages of the analogous quantities over an ensemble of classical Ising models. - Highlights: Black-Right-Pointing-Pointer Partition function of spin chains of Haldane-Shastry type in magnetic field. Black-Right-Pointing-Pointer Equivalence to classical inhomogeneous Ising models. Black-Right-Pointing-Pointer Free energy per site, other thermodynamic quantities in thermodynamic limit. Black-Right-Pointing-Pointer Zero field, zero temperature limits. Black-Right-Pointing-Pointer Thermodynamic equivalence with ensemble of classical Ising models.

  9. Development of the diabetes typology model for discerning Type 2 diabetes mellitus with national survey data

    Science.gov (United States)

    Bellatorre, Anna; Jackson, Sharon H.

    2017-01-01

    Objective To classify individuals with diabetes mellitus (DM) into DM subtypes using population-based studies. Design Population-based survey Setting Individuals participated in 2003–2004, 2005–2006, or 2009–2010 the National Health and Nutrition Examination Survey (NHANES), and 2010 Coronary Artery Risk Development in Young Adults (CARDIA) survey (research materials obtained from the National Heart, Lung, and Blood Institute Biologic Specimen and Data Repository Information Coordinating Center) Participants 3084, 3040 and 3318 US adults from the 2003–2004, 2005–2006 and 2009–2010 NHANES samples respectively, and 5,115 US adults in the CARDIA cohort Primary outcome measures We proposed the Diabetes Typology Model (DTM) through the use of six composite measures based on the Homeostatic Model Assessment (HOMA-IR, HOMA-%β, high HOMA-%S), insulin and glucose levels, and body mass index and conducted latent class analyses to empirically classify individuals into different classes. Results Three empirical latent classes consistently emerged across studies (entropy = 0.81–0.998). These three classes were likely Type 1 DM, likely Type 2 DM, and atypical DM. The classification has high sensitivity (75.5%), specificity (83.3%), and positive predictive value (97.4%) when validated against C-peptide level. Correlates of Type 2 DM were significantly associated with model-identified Type 2 DM. Compared to regression analysis on known correlates of Type 2 DM using all diabetes cases as outcomes, using DTM to remove likely Type 1 DM and atypical DM cases results in a 2.5–5.3% r-square improvement in the regression analysis, as well as model fits as indicated by significant improvement in -2 log likelihood (pwaist circumference), which provide additional validation of the DTM-defined classes. Conclusions Our Diabetes Typology Model reflects a promising first step toward discerning likely DM types from population-based data. This novel tool will improve how large

  10. Computational Software to Fit Seismic Data Using Epidemic-Type Aftershock Sequence Models and Modeling Performance Comparisons

    Science.gov (United States)

    Chu, A.

    2016-12-01

    Modern earthquake catalogs are often analyzed using spatial-temporal point process models such as the epidemic-type aftershock sequence (ETAS) models of Ogata (1998). My work implements three of the homogeneous ETAS models described in Ogata (1998). With a model's log-likelihood function, my software finds the Maximum-Likelihood Estimates (MLEs) of the model's parameters to estimate the homogeneous background rate and the temporal and spatial parameters that govern triggering effects. EM-algorithm is employed for its advantages of stability and robustness (Veen and Schoenberg, 2008). My work also presents comparisons among the three models in robustness, convergence speed, and implementations from theory to computing practice. Up-to-date regional seismic data of seismic active areas such as Southern California and Japan are used to demonstrate the comparisons. Data analysis has been done using computer languages Java and R. Java has the advantages of being strong-typed and easiness of controlling memory resources, while R has the advantages of having numerous available functions in statistical computing. Comparisons are also made between the two programming languages in convergence and stability, computational speed, and easiness of implementation. Issues that may affect convergence such as spatial shapes are discussed.

  11. Towards downscaling precipitation for Senegal - An approach based on generalized linear models and weather types

    Science.gov (United States)

    Rust, H. W.; Vrac, M.; Lengaigne, M.; Sultan, B.

    2012-04-01

    Changes in precipitation patterns with potentially less precipitation and an increasing risk for droughts pose a threat to water resources and agricultural yields in Senegal. Precipitation in this region is dominated by the West-African Monsoon being active from May to October, a seasonal pattern with inter-annual to decadal variability in the 20th century which is likely to be affected by climate change. We built a generalized linear model for a full spatial description of rainfall in Senegal. The model uses season, location, and a discrete set of weather types as predictors and yields a spatially continuous description of precipitation occurrences and intensities. Weather types have been defined on NCEP/NCAR reanalysis using zonal and meridional winds, as well as relative humidity. This model is suitable for downscaling precipitation, particularly precipitation occurrences relevant for drough risk mapping.

  12. Bayesian Estimation and Prediction for Flexible Weibull Model under Type-II Censoring Scheme

    Directory of Open Access Journals (Sweden)

    Sanjay Kumar Singh

    2013-01-01

    Full Text Available We have developed the Bayesian estimation procedure for flexible Weibull distribution under Type-II censoring scheme assuming Jeffrey's scale invariant (noninformative and Gamma (informative priors for the model parameters. The interval estimation for the model parameters has been performed through normal approximation, bootstrap, and highest posterior density (HPD procedures. Further, we have also derived the predictive posteriors and the corresponding predictive survival functions for the future observations based on Type-II censored data from the flexible Weibull distribution. Since the predictive posteriors are not in the closed form, we proposed to use the Monte Carlo Markov chain (MCMC methods to approximate the posteriors of interest. The performance of the Bayes estimators has also been compared with the classical estimators of the model parameters through the Monte Carlo simulation study. A real data set representing the time between failures of secondary reactor pumps has been analysed for illustration purpose.

  13. Artificial neural network approach to modelling of metal contents in different types of chocolates.

    Science.gov (United States)

    Podunavac-Kuzmanović, Sanja; Jevrić, Lidija; Švarc-Gajić, Jaroslava; Kovačević, Strahinja; Vasiljević, Ivana; Kecojević, Isidora; Ivanović, Evica

    2015-01-01

    The relationships between the contents of various metals in different types of chocolates were studied using chemometric approach. Chemometric analysis was based on the application of artificial neural networks (ANN). ANN was performed in order to select the significant models for predicting the metal contents. ANN equations, that represent the content of one metal as a function of the contents of other metals were established. The statistical quality of the generated mathematical models was determined by standard statistical measures and cross-validation parameters. High agreement between experimental and predicted values, obtained in the validation procedure, indicated the good quality of the models. The obtained results indicate the possibility of predicting the metal contents in different types of chocolate.

  14. Opinion dynamics: inhomogeneous Boltzmann-type equations modelling opinion leadership and political segregation

    CERN Document Server

    Düring, Bertram

    2015-01-01

    We propose and investigate different kinetic models for opinion formation, when the opinion formation process depends on an additional independent variable, e.g. a leadership or a spatial variable. More specifically, we consider:(i) opinion dynamics under the effect of opinion leadership, where each individual is characterised not only by its opinion, but also by another independent variable which quantifies leadership qualities; (ii) opinion dynamics modelling political segregation in the `The Big Sort', a phenomenon that US citizens increasingly prefer to live in neighbourhoods with politically like-minded individuals. Based on microscopic opinion consensus dynamics such models lead to inhomogeneous Boltzmann-type equations for the opinion distribution. We derive macroscopic Fokker-Planck-type equations in a quasi-invariant opinion limit and present results of numerical experiments.

  15. USTIFICATION OF A TWO-DIMENSIONAL NONLINEAR SHELL MODEL OF KOITER'S TYPE

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    A two-dimensional nonlinear shell model"of Koiter's type"has recently been proposed by the first author. It is shown here that, according to two mutually exclusive sets of assumptions bearing on the associated manifold of admissible inextensional displacements, the leading term of a formal asymptotic expansion of the solution of this two-dimensional model, with the thickness as the"small" parameter, satisfies either the two-dimensional equations of a nonlinearly elastic "membrane" shell or those of a nonlinearly elastic "flexural" shell. These conclusions being identical to those recently drawn by B. Miara, then by V. Lods and B. Miara, for the leading term of a formal asymptotic expansion of the solution of the equations of three-dimensional nonlinear elasticity, again with the thickness as the "small" parameter, the nonlinear shell model of Koiter's type considered here is thus justified, at least formally.

  16. Implementation of IEC Generic Model of Type 1 Wind Turbine Generator in DIgSILENT PowerFactory

    DEFF Research Database (Denmark)

    Zhao, Haoran; Wu, Qiuwei; Margaris, Ioannis;

    2013-01-01

    The implementation method for the International Electrotechnical Commission (IEC) generic models of Type 1 wind turbine generator (WTG) in DIgSILENT PowerFactory is presented. The following items are described, i.e. model structure, model blocks and how to implement these blocks in the Power......Factory environment. Case studies under both normal and fault conditions are done with the implemented IEC generic models of Type 1 WTG, and dynamic responses are captured and analyzed. The case study results show that the IEC generic models of Type 1 WTG can correctly represent the performances of Type 1 WTG under...

  17. Implementation of IEC Generic Models of Type 1 Wind Turbine Generator in DIgSILENT PowerFactory

    Institute of Scientific and Technical Information of China (English)

    Haoran ZHAO; Qiuwei WU; Ioannis MARGARIS; Poul S(O)RENSEN

    2013-01-01

    The implementation method for the International Electrotechnical Commission (IEC) generic models of Type 1 wind turbine generator (WTG) in DIgSILENT PowerFactory is presented.The following items are described,i.e.model structure,model blocks and how to implement these blocks in the PowerFactory environment.Case studies under both normal and fault conditions are done with the implemented IEC generic models of Type 1 WTG,and dynamic responses are captured and analyzed.The case study results show that the IEC generic models of Type 1 WTG can correctly represent the performances of Type 1 WTG under both normal and fault conditions.

  18. Deformed Type 0A Matrix Model and Super-Liouville Theory for Fermionic Black Holes

    CERN Document Server

    Ahn, C; Park, J; Suyama, T; Yamamoto, M; Ahn, Changrim; Kim, Chanju; Park, Jaemo; Suyama, Takao; Yamamoto, Masayoshi

    2006-01-01

    We consider a ${\\hat c}=1$ model in the fermionic black hole background. For this purpose we consider a model which contains both the N=1 and the N=2 super-Liouville interactions. We propose that this model is dual to a recently proposed type 0A matrix quantum mechanics model with vortex deformations. We support our conjecture by showing that non-perturbative corrections to the free energy computed by both the matrix model and the super-Liouville theories agree exactly by treating the N=2 interaction as a small perturbation. We also show that a two-point function on sphere calculated from the deformed type 0A matrix model is consistent with that of the N=2 super-Liouville theory when the N=1 interaction becomes small. This duality between the matrix model and super-Liouville theories leads to a conjecture for arbitrary $n$-point correlation functions of the N=1 super-Liouville theory on the sphere.

  19. Deficiencies in the simulation of the geographic distribution of climate types by global climate models

    Science.gov (United States)

    Zhang, Xianliang; Yan, Xiaodong

    2016-05-01

    The performances of General Circulation Models (GCMs) when checked with conventional methods (i.e. correlation, bias, root-mean-square error) can only be evaluated for each variable individually. The geographic distribution of climate type in GCM simulations, which reflects the spatial attributes of models and is related closely to the terrestrial biosphere, has not yet been evaluated. Thus, whether the geographic distribution of climate types was well simulated by GCMs was evaluated in this study for nine GCMs. The results showed that large areas of climate zones classified by the GCMs were allocated incorrectly when compared to the basic climate zones established by observed data. The percentages of wrong areas covered approximately 30-50 % of the total land area for most models. In addition, the temporal shift in the distribution of climate zones according to the GCMs was found to be inaccurate. Not only were the locations of shifts poorly simulated, but also the areas of shift in climate zones. Overall, the geographic distribution of climate types was not simulated well by the GCMs, nor was the temporal shift in the distribution of climate zones. Thus, a new method on how to evaluate the simulated distribution of climate types for GCMs was provided in this study.

  20. Late-time behaviour of the tilted Bianchi type VIh models

    Science.gov (United States)

    Hervik, S.; van den Hoogen, R. J.; Lim, W. C.; Coley, A. A.

    2007-08-01

    We study tilted perfect fluid cosmological models with a constant equation of state parameter in spatially homogeneous models of Bianchi type VIh using dynamical systems methods and numerical experimentation, with an emphasis on their future asymptotic evolution. We determine all of the equilibrium points of the type VIh state space (which correspond to exact self-similar solutions of the Einstein equations, some of which are new), and their stability is investigated. We find that there are vacuum plane-wave solutions that act as future attractors. In the parameter space, a 'loophole' is shown to exist in which there are no stable equilibrium points. We then show that a Hopf-bifurcation can occur resulting in a stable closed orbit (which we refer to as the Mussel attractor) corresponding to points both inside the loophole and points just outside the loophole; in the former case the closed curves act as late-time attractors while in the latter case these attracting curves will co-exist with attracting equilibrium points. In the special Bianchi type III case, centre manifold theory is required to determine the future attractors. Comprehensive numerical experiments are carried out to complement and confirm the analytical results presented. We note that the Bianchi type VIh case is of particular interest in that it contains many different subcases which exhibit many of the different possible future asymptotic behaviours of Bianchi cosmological models.

  1. Network-based analysis of affected biological processes in type 2 diabetes models.

    Directory of Open Access Journals (Sweden)

    Manway Liu

    2007-06-01

    Full Text Available Type 2 diabetes mellitus is a complex disorder associated with multiple genetic, epigenetic, developmental, and environmental factors. Animal models of type 2 diabetes differ based on diet, drug treatment, and gene knockouts, and yet all display the clinical hallmarks of hyperglycemia and insulin resistance in peripheral tissue. The recent advances in gene-expression microarray technologies present an unprecedented opportunity to study type 2 diabetes mellitus at a genome-wide scale and across different models. To date, a key challenge has been to identify the biological processes or signaling pathways that play significant roles in the disorder. Here, using a network-based analysis methodology, we identified two sets of genes, associated with insulin signaling and a network of nuclear receptors, which are recurrent in a statistically significant number of diabetes and insulin resistance models and transcriptionally altered across diverse tissue types. We additionally identified a network of protein-protein interactions between members from the two gene sets that may facilitate signaling between them. Taken together, the results illustrate the benefits of integrating high-throughput microarray studies, together with protein-protein interaction networks, in elucidating the underlying biological processes associated with a complex disorder.

  2. Different developmental trajectories across feature types support a dynamic field model of visual working memory development.

    Science.gov (United States)

    Simmering, Vanessa R; Miller, Hilary E; Bohache, Kevin

    2015-05-01

    Research on visual working memory has focused on characterizing the nature of capacity limits as "slots" or "resources" based almost exclusively on adults' performance with little consideration for developmental change. Here we argue that understanding how visual working memory develops can shed new light onto the nature of representations. We present an alternative model, the Dynamic Field Theory (DFT), which can capture effects that have been previously attributed either to "slot" or "resource" explanations. The DFT includes a specific developmental mechanism to account for improvements in both resolution and capacity of visual working memory throughout childhood. Here we show how development in the DFT can account for different capacity estimates across feature types (i.e., color and shape). The current paper tests this account by comparing children's (3, 5, and 7 years of age) performance across different feature types. Results showed that capacity for colors increased faster over development than capacity for shapes. A second experiment confirmed this difference across feature types within subjects, but also showed that the difference can be attenuated by testing memory for less familiar colors. Model simulations demonstrate how developmental changes in connectivity within the model-purportedly arising through experience-can capture differences across feature types.

  3. Force transfer model and characteristics of hybrid transducer type ultrasonic motors.

    Science.gov (United States)

    Guo, Jifeng; Gong, Shujuan; Guo, Haixun; Liu, Xiao; Ji, Kehui

    2004-04-01

    The characteristics of longitudinal-torsional hybrid transducer-type ultrasonic motors (HTUSM) are low speed and high torque. The discontinuous-surface-contact mode between the stator and the rotor is different from the many-point-contact mode of traveling wave motors, which is also an essential cause for high torque. Therefore, it is important to analyze its force transfer model between the rotor and the stator. In this paper, issues of using the method of equivalent circuit model are addressed. The relationships between the contact angle, preload, and physical parameters of frictional materials are given, according to the impulse conservation law axially. The equations describing output torque, amplitudes of longitudinal and torsional vibration, and parameters of the rotor are derived according to the principle that the work done by the load is equal to that by the driving force in one vibrating cycle. All factors that influence the mechanical characteristics are analyzed, and accuracy and suitability of the force transfer model are verified by comparison with the prototype motor. The formula for transfer efficiency on the stator/rotor interface is given, and the low-efficiency of this type motor is explained. The wide-working frequency range property of this type motor is shown with experimental results. Based on this study, the parameters of the rotor and preload are determined. The maximum torque of the prototype motor is up to 13.2 nm, and no-load speed of this type of motor is 12.5 rpm.

  4. Comparison of renormalization group schemes for sine-Gordon type models

    CERN Document Server

    Nandori, I; Sailer, K; Trombettoni, A

    2009-01-01

    We consider the scheme-dependence of the renormalization group (RG) flow obtained in the local potential approximation for two-dimensional periodic, sine-Gordon type field-theoric models with possible inclusion of explicit mass terms. For sine-Gordon type models showing up a Kosterlitz-Thouless-Berezinskii type phase transition the Wegner-Houghton, the Polchinski, the functional Callan-Symanzik and the effective average action RG methods give qualitatively the same result and the critical frequency (temperature) can be obtained scheme-independently from the RG equations linearized around the Gaussian fixed point. For the massive sine-Gordon model which undergoes an Ising type phase transition, the Wegner-Houghton, the functional Callan-Symanzik and the effective average action RG methods provide the same scheme-independent phase structure and value for the critical ratio, in agreement with the results of lattice methods. It is also shown that RG equations linearized around the Gaussian fixed point produce sch...

  5. Bianchi Type-Ⅲ String Cosmological Model With Bulk Viscosity and Magnetic Field

    Institute of Scientific and Technical Information of China (English)

    WANG Xing-Xiang

    2006-01-01

    @@ The Bianchi type-Ⅲ cosmological model for a cloud string in the presence of bulk viscosity and magnetic field are presented. To obtain the determinate model it is assumed that there is an equation of state ρ = kλ and the scalar of expansion is proportional to the shear scalar θ∝σ, which leads to a relation between metric potentials B = mCn. The physical and geometric aspects of the model are also discussed. The model describes a shearing non-rotating continuously expanding universe with a big-bang start. In the absence of magnetic field, it reduces to the string model with bulk viscosity that was previously given in the literature.

  6. On the Range of Validity and Accuracy of Boussinesq-Type Models

    Institute of Scientific and Technical Information of China (English)

    许泰文; 杨炳达; 曾以帆

    2004-01-01

    In this paper the range of validity and comparison of accuracy of three Boussinesq-type models (Madsen and Sφrensen, 1992; Nwogu, 1993; Wei et al., 1995; referred to as MS, NW and WKGS, respectively) are analyzed and discussed. The governing equations are extended to the second-order approximations to keep higher-order nonlinear terms. Two key parameters ε andμ representing wave nonlinear and frequency dispersive properties are used to demarcate the limit of applicability for these three models. The accuracy of predictions by each model is compared by the relative errors with and without higher-order nonlinear terms in Boussinesq equations. A numerical model is developed based on one-dimensional Boussinesq equations and applied to the case of waves propagating over a submerged bar. The performance and feasibility of each model are tested against laboratory data.

  7. Hydrodynamical model atmospheres: Their impact on stellar spectroscopy and asteroseismology of late-type stars

    CERN Document Server

    Ludwig, Hans-G

    2016-01-01

    Hydrodynamical, i.e. multi-dimensional and time-dependent, model atmospheres of late-type stars have reached a high level of realism. They are commonly applied in high-fidelity work on stellar abundances but also allow the study of processes that are not modelled in standard, one-dimensional hydrostatic model atmospheres. Here, we discuss two observational aspects that emerge from such processes, the photometric granulation background and the spectroscopic microturbulence. We use CO5BOLD hydrodynamical model atmospheres to characterize the total granular brightness fluctuations and characteristic time scale for FGK stars. Emphasis is put on the diagnostic potential of the granulation background for constraining the fundamental atmospheric parameters. We find a clear metallicity dependence of the granulation background. The comparison between the model predictions and available observational constraints at solar metallicity shows significant differences, that need further clarification. Concerning microturbule...

  8. The female gametophyte: an emerging model for cell type-specific systems biology in plant development

    Directory of Open Access Journals (Sweden)

    Marc William Schmid

    2015-11-01

    Full Text Available Systems biology, a holistic approach describing a system emerging from the interactions of its molecular components, critically depends on accurate qualitative determination and quantitative measurements of these components. Development and improvement of large-scale profiling methods (omics now facilitates comprehensive measurements of many relevant molecules. For multicellular organisms, such as animals, fungi, algae, and plants, the complexity of the system is augmented by the presence of specialized cell types and organs, and a complex interplay within and between them. Cell type-specific analyses are therefore crucial for the understanding of developmental processes and environmental responses. This review first gives an overview of current methods used for large-scale profiling of specific cell types exemplified by recent advances in plant biology. The focus then lies on suitable model systems to study plant development and cell type specification. We introduce the female gametophyte of flowering plants as an ideal model to study fundamental developmental processes. Moreover, the female reproductive lineage is of importance for the emergence of evolutionary novelties such as an unequal parental contribution to the tissue nurturing the embryo or the clonal production of seeds by asexual reproduction (apomixis. Understanding these processes is not only interesting from a developmental or evolutionary perspective, but bears great potential for further crop improvement and the simplification of breeding efforts. We finally highlight novel methods, which are already available or which will likely soon facilitate large-scale profiling of the specific cell types of the female gametophyte in both model and non-model species. We conclude that it may take only few years until an evolutionary systems biology approach toward female gametogenesis may decipher some of its biologically most interesting and economically most valuable processes.

  9. Cosmological model with fermion and tachyon fields interacting via Yukawa-type potential

    Science.gov (United States)

    Ribas, Marlos O.; Devecchi, Fernando P.; Kremer, Gilberto M.

    2016-02-01

    A model for the universe with tachyonic and fermionic fields interacting through a Yukawa-type potential is investigated. It is shown that the tachyonic field answers for the initial accelerated regime and for the subsequent decelerated regime so that it behaves as an inflaton at early times and as a matter field at intermediate times, while the fermionic field has the role of a dark energy constituent, since it leads to an accelerated regime at later times. The interaction between the fields via a Yukawa-type potential controls the duration of the decelerated era, since a stronger coupling makes a shorter decelerated period.

  10. Modelling the IDV Emissions of the BL Lac Objects with a Langevin Type Stochastic Differential Equation

    Indian Academy of Sciences (India)

    C. S. Leung; J. Y. Wei; T. Harko; Z. Kovacs

    2011-03-01

    In this paper, we introduce a simplified model for explaining the observations of optical intra-day variability (IDV) of the BL Lac Objects. We assume that the source of the IDV are the stochastic oscillations of an accretion disk around a supermassive black hole. The stochastic fluctuations on the vertical direction of the accretion disk are described by using a Langevin type equation with a damping term and a random, white noise type force. Furthermore, preliminary numerical simulation results are presented, which are based on the numerical analysis of the Langevin stochastic differential equation.

  11. Cosmological model with fermion and tachyon fields interacting via Yukawa-type potential

    CERN Document Server

    Ribas, Marlos O; Kremer, Gilberto M

    2016-01-01

    A model for the universe with tachyonic and fermionic fields interacting through a Yukawa-type potential is investigated. It is shown that the tachyonic field answers for the initial accelerated regime and for the subsequent decelerated regime so that it behaves as an inflaton at early times and as a matter field at intermediate times, while the fermionic field has the role of a dark energy constituent, since it leads to an accelerated regime at later times. The interaction between the fields via a Yukawa-type potential controls the duration of the decelerated era, since a stronger coupling makes a shorter decelerated period.

  12. The lack of theoretical support for using person trade-offs in QALY-type models

    DEFF Research Database (Denmark)

    Østerdal, Lars Peter Raahave

    2009-01-01

    Considerable support for the use of person trade-off methods to assess the quality-adjustment factor in quality-adjusted life years (QALY) models has been expressed in the literature. The WHO has occasionally used similar methods to assess the disability weights for calculation of disability......-adjusted life years (DALYs). This paper discusses the theoretical support for the use of person trade-offs in QALY-type measurement of (changes in) population health. It argues that measures of this type based on such quality-adjustment factors almost always violate the Pareto principle, and so lack normative...

  13. Investigation of stress and displacement fields in a planar model of Y type seals

    Energy Technology Data Exchange (ETDEWEB)

    Huang, Z.; Yang, M.; Zhang, B.; Huang, H.

    1986-01-01

    To provide necessary information for working out the national standard for Y type seals, the authors investigated the stress and displacement fields of Y type seals under load. Models used as seals for the test were made of polyurethane rubber. Photoelastic method was used to measure stress and a new moire-grid method, which requires a grating with dragging along system was used to measure displacement under limited deformation. The test has shown that the sealing behavior is mainly dependent on the structure of the sealing lip, which is liable to wearing out. 6 references, 9 figures.

  14. Modeling and forecasting crude oil markets using ARCH-type models

    Energy Technology Data Exchange (ETDEWEB)

    Cheong, Chin Wen [Research Centre of Mathematical Sciences, Faculty of Information Technology, Multimedia University, 63100 Cyberjaya, Selangor (Malaysia)

    2009-06-15

    This study investigates the time-varying volatility of two major crude oil markets, the West Texas Intermediate (WTI) and Europe Brent. A flexible autoregressive conditional heteroskedasticity (ARCH) model is used to take into account the stylized volatility facts such as clustering volatility, asymmetric news impact and long memory volatility among others. The empirical results indicate that the intensity of long-persistence volatility in the WTI is greater than in the Brent. It is also found that for the WTI, the appreciation and depreciation shocks of the WTI have similar impact on the resulting volatility. However, a leverage effect is found in Brent. Although both the estimation and diagnostic evaluations are in favor of an asymmetric long memory ARCH model, only the WTI models provide superior in the out-of-sample forecasts. On the other hand, from the empirical out-of-sample forecasts, it appears that the simplest parsimonious generalized ARCH provides the best forecasted evaluations for the Brent crude oil data. (author)

  15. Enhanced transmission of malaria parasites to mosquitoes in a murine model of type 2 diabetes.

    Science.gov (United States)

    Pakpour, Nazzy; Cheung, Kong Wai; Luckhart, Shirley

    2016-04-21

    More than half of the world's population is at risk of malaria and simultaneously, many malaria-endemic regions are facing dramatic increases in the prevalence of type 2 diabetes. Studies in murine malaria models have examined the impact of malaria infection on type 2 diabetes pathology, it remains unclear how this chronic metabolic disorder impacts the transmission of malaria. In this report, the ability type 2 diabetic rodents infected with malaria to transmit parasites to Anopheles stephensi mosquitoes is quantified. The infection prevalence and intensity of An. stephensi mosquitoes that fed upon control or type 2 diabetic C57BL/6 db/db mice infected with either lethal Plasmodium berghei NK65 or non-lethal Plasmodium yoelii 17XNL murine malaria strains were determined. Daily parasitaemias were also recorded. A higher percentage of mosquitoes (87.5 vs 61.5 % for P. yoelii and 76.9 vs 50 % for P. berghei) became infected following blood feeding on Plasmodium-infected type 2 diabetic mice compared to mosquitoes that fed on infected control animals, despite no significant differences in circulating gametocyte levels. These results suggest that type 2 diabetic mice infected with malaria are more efficient at infecting mosquitoes, raising the question of whether a similar synergy exists in humans.

  16. Exchangeable lead from prediction models relates to vetiver lead uptake in different soil types.

    Science.gov (United States)

    Andra, Syam S; Sarkar, Dibyendu; Saminathan, Sumathi K M; Datta, Rupali

    2011-12-01

    Prediction models for exchangeable soil lead, published earlier in this journal (Andra et al. 2010a), were developed using a suite of native lead (Pb) paint-contaminated residential soils from two US cities heavily populated with homes constructed prior to Pb ban in paints. In this study, we tested the feasibility and practical applications of these prediction models for developing a phytoremediation design using vetiver grass (Vetiveria zizanioides), a Pb-tolerant plant. The models were used to estimate the exchangeable fraction of Pb available for vetiver uptake in four lead-spiked soil types, both acidic and alkaline, with varying physico-chemical properties and that are different from those used to build the prediction models. Results indicate a strong correlation for predictable exchangeable Pb with the observed fraction and as well with total Pb accumulated by vetiver grass grown in these soils. The correlation coefficient for the predicted vs. observed exchangeable Pb with p vetiver grass with p < 0.001 was 0.948, 0.983, 0.929, and 0.969 for each soil type, respectively. This study suggests that the success of a phytoremediation design could be assessed upfront by predicting the exchangeable Pb fraction in a given soil type based on its properties. This helps in modifying the soil conditions to enhance phytoextraction of Pb from contaminated soils.

  17. A dynamical model for FR II type radio sources with terminated jet activity

    Science.gov (United States)

    Kuligowska, Elżbieta

    2017-02-01

    Context. The extension of the KDA analytical model of FR II-type source evolution originally assuming a continuum injection process in the jet-IGM interaction towards a case of the jet's termination is presented and briefly discussed. Aims: The dynamical evolution of FR II-type sources predicted with this extended model, hereafter referred to as KDA EXT, and its application to the chosen radio sources. Methods: Following the classical approach based on the source's continuous injection and self-similarity, I propose the effective formulae describing the length and luminosity evolution of the lobes during an absence of the jet flow, and present the resulting diagrams for the characteristics mentioned. Results: Using an algorithm based on the numerical integration of a modified formula for jet power, the KDA EXT model is fitted to three radio galaxies. Their predicted spectra are then compared to the observed spectra, proving that these fits are better than the best spectral fit provided by the original KDA model of the FR II-type sources dynamical evolution.

  18. Public health program planning logic model for community engaged type 2 diabetes management and prevention.

    Science.gov (United States)

    West, Joseph F

    2014-02-01

    Diabetes remains a growing epidemic with widening health inequity gaps in disease management, self-management knowledge, access to care and outcomes. Yet there is a paucity of evaluation tools for community engaged interventions aimed at closing the gaps and improving health. The Guide to Community Preventive Services (the Community Guide) developed by the Task Force on Community Preventive Services (the Task Force) at the Centers for Disease Control and Prevention (CDC) recommends two healthcare system level interventions, case management interventions and disease management programs, to improve glycemic control. However, as a public health resource guide for diabetes interventions a model for community engagement is a glaringly absent component of the Community Guide recommendations. In large part there are few evidence-based interventions featuring community engagement as a practice and system-level focus of chronic disease and Type 2 diabetes management. The central argument presented in this paper is that the absence of these types of interventions is due to the lack of tools for modeling and evaluating such interventions, especially among disparate and poor populations. A conceptual model emphasizing action-oriented micro-level community engagement is needed to complement the Community Guide and serve as the basis for testing and evaluation of these kinds of interventions. A unique logic model advancing the Community Guide diabetes recommendations toward measureable and sustainable community engagement for improved Type 2 diabetes outcomes is presented. Copyright © 2013 Elsevier Ltd. All rights reserved.

  19. An analytical canopy-type model for wind farm-atmosphere interaction

    Science.gov (United States)

    Markfort, C. D.; Zhang, W.; Porte-Agel, F.

    2013-12-01

    We present a new model for the interactions between large-scale wind farms and the atmospheric boundary layer (ABL) based on similarity to canopy flows. Wind farms capture momentum from the atmospheric boundary layer both at the leading edge and from above. Based on our recent findings that turbulent flow in and above wind farms is similar to canopy-type flows, we examine this further with an analytical model that can predict the development length of the wind farm flow as well as vertical momentum absorption. Within the region of flow development, momentum is advected into the wind farm and wake turbulence draws excess momentum in from between turbines. This is characterized by large dispersive fluxes of momentum. Once the flow within the farm is developed, the area-averaged velocity profile exhibits an inflection point, characteristic of canopy-type flows. The inflected velocity profile is associated with the presence of a dominant characteristic turbulence scale, which may be responsible for a significant portion of the vertical momentum flux. Prediction of this scale is useful for determining the amount of available power for harvesting. The new model is tested with results from wind tunnel experiments, which characterize the turbulent flow in and above model wind farms. The model is useful for representing wind farms in meteorological and wind resource assessment models, for optimizing wind turbine spacing and layout, and for assessing the impacts of wind farms on nearby wind resources and the environment.

  20. Models for Predicting the Architecture of Different Shoot Types in Apple

    Science.gov (United States)

    Baïram, Emna; Delaire, Mickaël; Le Morvan, Christian; Buck-Sorlin, Gerhard

    2017-01-01

    In apple, the first-order branch of a tree has a characteristic architecture constituting three shoot types: bourses (rosettes), bourse shoots, and vegetative shoots. Its overall architecture as well as that of each shoot thus determines the distribution of sources (leaves) and sinks (fruits) and could have an influence on the amount of sugar allocated to fruits. Knowledge of architecture, in particular the position and area of leaves helps to quantify source strength. In order to reconstruct this initial architecture, rules equipped with allometric relations could be used: these allow predicting model parameters that are difficult to measure from simple traits that can be determined easily, non-destructively and directly in the orchard. Once such allometric relations are established they can be used routinely to recreate initial structures. Models based on allometric relations have been established in this study in order to predict the leaf areas of the three different shoot types of three apple cultivars with different branch architectures: “Fuji,” “Ariane,” and “Rome Beauty.” The allometric relations derived from experimental data allowed us to model the total shoot leaf area as well as the individual leaf area for each leaf rank, for each shoot type and each genotype. This was achieved using two easily measurable input variables: total leaf number per shoot and the length of the biggest leaf on the shoot. The models were tested using a different data set, and they were able to accurately predict leaf area of all shoot types and genotypes. Additional focus on internode lengths on spurs contributed to refine the models. PMID:28203241

  1. Python for hydrological modeling: interfacing C code with ctypes, dynamic typing and introspection

    Science.gov (United States)

    Bogaart, P. W.

    2008-12-01

    The Python programming language has several features that make it an ideal front-end language for user-friendly numerical modelling of hydrological systems. In this presentation we will demonstrate this with a comprehensive hillslope hydrological modelling framework, where the following features are highlighted: •[Extensibility:] Often a low-level langage like C is better suited for the core functionality of numerical models, for instance because of the inherent higher computational speed, or the availability of specialized algorithms, like the well-known Numerical Recipes or the open source GNU Scientific Library. The now standard Python "ctypes" enables easy manipulation of the C functions and datastructures, provided the C code is compiled into a shared library. High-level Python wrapper functions or classes are easily constructed. •[Flexibility and introspection:] Python is strong but dynamically typed, meaning that variables can change type. This enables the construction of highly flexible functions that operate on a single model parameter, or a list of parameters, or a function that yields parameter values. Related to this, is the capacity of Python to inspect its own types and variables during runtime. So, depending on the actual type of a function argument (scalar, list, function) different actions are taken. Python classes are highly flexibly in the sense that member fields can be added to them during runtime. Python's introspection capacities enables finding out which member fields are actually present. This enables the construction of 'smart' functions that probe an object for the presence or absence of specified members (using their name), and then taking action. On example that will be worked out is a flexible parameter optimizer that takes a reference to a model object, and a list of a parameter names that are to be optimized.

  2. Population pharmacokinetic modeling of glibenclamide in poorly controlled South African type 2 diabetic subjects

    Directory of Open Access Journals (Sweden)

    Rambiritch V

    2016-07-01

    Full Text Available Virendra Rambiritch,1 Poobalan Naidoo,2 Breminand Maharaj,1 Goonaseelan Pillai3 1University of KwaZulu-Natal, Durban, 2Department of Internal Medicine, RK Khan Regional Hospital, Chatsworth, South Africa; 3Novartis Pharma AG, Basel, Switzerland Aim: The aim of this study was to describe the pharmacokinetics (PK of glibenclamide in poorly controlled South African type 2 diabetic subjects using noncompartmental and model-based methods. Methods: A total of 24 subjects with type 2 diabetes were administered increasing doses (0 mg/d, 2.5 mg/d, 5 mg/d, 10 mg/d, and 20 mg/d of glibenclamide daily at 2-week intervals. Plasma glibenclamide, glucose, and insulin determinations were performed. Blood sampling times were 0 minute, 30 minutes, 60 minutes, 90 minutes, and 120 minutes (post breakfast sampling and 240 minutes, 270 minutes, 300 minutes, 330 minutes, 360 minutes, and 420 minutes (post lunch sampling on days 14, 28, 42, 56, and 70 for doses of 0 mg, 2.5 mg, 5.0 mg, 10 mg, and 20 mg, respectively. Blood sampling was performed after the steady state was reached.  A total of 24 individuals in the data set contributed to a total of 841 observation records. The PK was analyzed using noncompartmental analysis methods, which were implemented in WinNonLin®, and population PK analysis using NONMEM®. Glibenclamide concentration data were log transformed prior to fitting. Results: A two-compartmental disposition model was selected after evaluating one-, two-, and three-compartmental models to describe the time course of glibenclamide plasma concentration data. The one-compartment model adequately described the data; however, the two-compartment model provided a better fit. The three-compartment model failed to achieve successful convergence. A more complex model, to account for enterohepatic recirculation that was observed in the data, was unsuccessful. Conclusion: In South African diabetic subjects, glibenclamide demonstrates linear PK and was best

  3. Fuzzy-logic modeling of Fenton's strong chemical oxidation process treating three types of landfill leachates.

    Science.gov (United States)

    Sari, Hanife; Yetilmezsoy, Kaan; Ilhan, Fatih; Yazici, Senem; Kurt, Ugur; Apaydin, Omer

    2013-06-01

    Three multiple input and multiple output-type fuzzy-logic-based models were developed as an artificial intelligence-based approach to model a novel integrated process (UF-IER-EDBM-FO) consisted of ultrafiltration (UF), ion exchange resins (IER), electrodialysis with bipolar membrane (EDBM), and Fenton's oxidation (FO) units treating young, middle-aged, and stabilized landfill leachates. The FO unit was considered as the key process for implementation of the proposed modeling scheme. Four input components such as H(2)O(2)/chemical oxygen demand ratio, H(2)O(2)/Fe(2+) ratio, reaction pH, and reaction time were fuzzified in a Mamdani-type fuzzy inference system to predict the removal efficiencies of chemical oxygen demand, total organic carbon, color, and ammonia nitrogen. A total of 200 rules in the IF-THEN format were established within the framework of a graphical user interface for each fuzzy-logic model. The product (prod) and the center of gravity (centroid) methods were performed as the inference operator and defuzzification methods, respectively, for the proposed prognostic models. Fuzzy-logic predicted results were compared to the outputs of multiple regression models by means of various descriptive statistical indicators, and the proposed methodology was tested against the experimental data. The testing results clearly revealed that the proposed prognostic models showed a superior predictive performance with very high determination coefficients (R (2)) between 0.930 and 0.991. This study indicated a simple means of modeling and potential of a knowledge-based approach for capturing complicated inter-relationships in a highly non-linear problem. Clearly, it was shown that the proposed prognostic models provided a well-suited and cost-effective method to predict removal efficiencies of wastewater parameters prior to discharge to receiving streams.

  4. A-Priori Rupture Models for Northern California Type-A Faults

    Science.gov (United States)

    Wills, Chris J.; Weldon, Ray J.; Field, Edward H.

    2008-01-01

    This appendix describes how a-priori rupture models were developed for the northern California Type-A faults. As described in the main body of this report, and in Appendix G, ?a-priori? models represent an initial estimate of the rate of single and multi-segment surface ruptures on each fault. Whether or not a given model is moment balanced (i.e., satisfies section slip-rate data) depends on assumptions made regarding the average slip on each segment in each rupture (which in turn depends on the chosen magnitude-area relationship). Therefore, for a given set of assumptions, or branch on the logic tree, the methodology of the present Working Group (WGCEP-2007) is to find a final model that is as close as possible to the a-priori model, in the least squares sense, but that also satisfies slip rate and perhaps other data. This is analogous the WGCEP- 2002 approach of effectively voting on the relative rate of each possible rupture, and then finding the closest moment-balance model (under a more limiting set of assumptions than adopted by the present WGCEP, as described in detail in Appendix G). The 2002 Working Group Report (WCCEP, 2003, referred to here as WGCEP-2002), created segmented earthquake rupture forecast models for all faults in the region, including some that had been designated as Type B faults in the NSHMP, 1996, and one that had not previously been considered. The 2002 National Seismic Hazard Maps used the values from WGCEP-2002 for all the faults in the region, essentially treating all the listed faults as Type A faults. As discussed in Appendix A, the current WGCEP found that there are a number of faults with little or no data on slip-per-event, or dates of previous earthquakes. As a result, the WGCEP recommends that faults with minimal available earthquake recurrence data: the Greenville, Mount Diablo, San Gregorio, Monte Vista-Shannon and Concord-Green Valley be modeled as Type B faults to be consistent with similarly poorly-known faults statewide

  5. Bayesian hierarchical models combining different study types and adjusting for covariate imbalances: a simulation study to assess model performance.

    Directory of Open Access Journals (Sweden)

    C Elizabeth McCarron

    Full Text Available BACKGROUND: Bayesian hierarchical models have been proposed to combine evidence from different types of study designs. However, when combining evidence from randomised and non-randomised controlled studies, imbalances in patient characteristics between study arms may bias the results. The objective of this study was to assess the performance of a proposed Bayesian approach to adjust for imbalances in patient level covariates when combining evidence from both types of study designs. METHODOLOGY/PRINCIPAL FINDINGS: Simulation techniques, in which the truth is known, were used to generate sets of data for randomised and non-randomised studies. Covariate imbalances between study arms were introduced in the non-randomised studies. The performance of the Bayesian hierarchical model adjusted for imbalances was assessed in terms of bias. The data were also modelled using three other Bayesian approaches for synthesising evidence from randomised and non-randomised studies. The simulations considered six scenarios aimed at assessing the sensitivity of the results to changes in the impact of the imbalances and the relative number and size of studies of each type. For all six scenarios considered, the Bayesian hierarchical model adjusted for differences within studies gave results that were unbiased and closest to the true value compared to the other models. CONCLUSIONS/SIGNIFICANCE: Where informed health care decision making requires the synthesis of evidence from randomised and non-randomised study designs, the proposed hierarchical Bayesian method adjusted for differences in patient characteristics between study arms may facilitate the optimal use of all available evidence leading to unbiased results compared to unadjusted analyses.

  6. Different Types of Solitary Wave Scattering in the Fermi-Pasta-Ulam Model

    Institute of Scientific and Technical Information of China (English)

    WEN Zhen-Ying; ZHAO Hong

    2005-01-01

    @@ We show that the scattering between two solitary waves in the Fermi-Pasta-Ulam model with interaction potential V(x) = αx2/2 + x4/4 can be classified into four types according to the configurations of the solitary waves. For three of the four types, the large solitary wave can lose energy and the small one can gain in average by collision.For the other one type in a special parameter region we encounter an anomalous scattering, i.e. the large solitary wave gains energy and the small one loses energy. Numerical investigations are performed for the anharmonic limit case of α = 0 and the general case of α≠ 0 and comparisons between them are made.

  7. New Experimental Models of Diabetic Nephropathy in Mice Models of Type 2 Diabetes: Efforts to Replicate Human Nephropathy

    Directory of Open Access Journals (Sweden)

    María José Soler

    2012-01-01

    Full Text Available Diabetic nephropathy (DN is the leading cause of end-stage renal disease. The use of experimental models of DN has provided valuable information regarding many aspects of DN, including pathophysiology, progression, implicated genes, and new therapeutic strategies. A large number of mouse models of diabetes have been identified and their kidney disease was characterized to various degrees. Most experimental models of type 2 DN are helpful in studying early stages of DN, but these models have not been able to reproduce the characteristic features of more advanced DN in humans such as nodules in the glomerular tuft or glomerulosclerosis. The generation of new experimental models of DN created by crossing, knockdown, or knockin of genes continues to provide improved tools for studying DN. These models provide an opportunity to search for new mechanisms involving the development of DN, but their shortcomings should be recognized as well. Moreover, it is important to recognize that the genetic background has a substantial effect on the susceptibility to diabetes and kidney disease development in the various models of diabetes.

  8. Numerical modeling and design of a disk-type rotating permanent magnet induction pump

    Energy Technology Data Exchange (ETDEWEB)

    Koroteeva, E., E-mail: koroteeva@physics.msu.ru [Institute of Physics of University of Latvia, Salaspils 2169 (Latvia); Lomonosov Moscow State University, Moscow 119991 (Russian Federation); Ščepanskis, M. [Laboratory for Mathematical Modelling of Environmental and Technological Processes, University of Latvia, Rīga 1002 (Latvia); Bucenieks, I.; Platacis, E. [Institute of Physics of University of Latvia, Salaspils 2169 (Latvia)

    2016-05-15

    Highlights: • The design and performance of a disk-type induction pump are described. • A 3D numerical model based on an iterative coupling between EM and hydrodynamic solvers is developed. • The model is verified by comparing with the experiments in a Pb-Bi loop facility. • The suggestions are given to estimate the pump performance in a Pb-Li loop at high pressures. - Abstract: Electromagnetic induction pumps with rotating permanent magnets appear to be the most promising devices to transport liquid metals in high-temperature applications. Here we present a numerical methodology to simulate the operation of one particular modification of these types of pumps: a disk-type induction pump. The numerical model allows for the calculation and analysis of the flow parameters, including the pressure–flow rate characteristics of the pump. The simulations are based on an iterative fully coupled scheme for electromagnetic and hydrodynamic solvers. The developed model is verified by comparing with experimental data obtained using a Pb-Bi loop test facility, for pressures up to 4 bar and flow rates up to 9 kg/s. The verified model is then expanded to higher pressures, beyond the limits of the experimental loop. Based on the numerical simulations, suggestions are given to extrapolate experimental data to higher (industrially important) pressure ranges. Using the numerical model and analytical estimation, the pump performance for the Pb-Li loop is also examined, and the ability of the designed pump to develop pressure heads over 6 bar and to provide flow rates over 15 kg/s is shown.

  9. Accelerating dark energy models with anisotropic fluid in Bianchi type Ⅵ0 space-time

    Institute of Scientific and Technical Information of China (English)

    Anirudh Pradhan

    2013-01-01

    Motivated by the increasing evidence for the need of a geometry that resembles Bianchi morphology to explain the observed anisotropy in the WMAP data,we have discussed some features of Bianchi type Ⅵ0 universes in the presence of a fluid that has an anisotropic equation of state (EoS) parameter in general relativity.We present two accelerating dark energy (DE) models with an anisotropic fluid in Bianchi type Ⅵ0 space-time.To ensure a deterministic solution,we choose the scale factor a(t) =(√tnet),which yields a time-dependent deceleration parameter,representing a class of models which generate a transition of the universe from the early decelerating phase to the recent accelerating phase.Under suitable conditions,the anisotropic models approach an isotropic scenario.The EoS for DE ω is found to be time-dependent and its existing range for derived models is in good agreement with data from recent observations of type Ⅰa supernovae (SNe Ⅰa) (Knop et al.2003),SNe Ⅰa data combined with cosmic microwave background (CMB) anisotropy and galaxy clustering statistics (Tegmark et al.2004a),as well as the latest combination of cosmological datasets coming from CMB anisotropies,luminosity distances of high redshift SNe Ⅰa and galaxy clustering.For different values of n,we can generate a class of physically viable DE models.The cosmological constant Λ is found to be a positive decreasing function of time and it approaches a small positive value at late time (i.e.the present epoch),which is corroborated by results from recent SN Ⅰa observations.We also observe that our solutions are stable.The physical and geometric aspects of both models are also discussed in detail.

  10. A Study of Enhanced, Higher Order Boussinesq-Type Equations and Their Numerical Modelling

    DEFF Research Database (Denmark)

    Banijamali, Babak

    potential for applications to the realm of numerical modelling in coastal engineering. The derivation and analysis of several forms of higher-order in dispersion and non-linearity Boussinesq-type equations have been undertaken, obtaining and investigating the properties of a new and generalised class...... discretisation methods. The analysis categorises the errors of the semidiscretised and the fully-discretised equations into the categories of spurious dispersion and spurious diffusion. In particular, issues of numerical wave refraction and numerical wave blocking are introduced and addressed in the contexts...... is realizable. These tests also provided a venue for the practical investigation of the linear and nonlinear properties of the numerical models in the sense of the type of discretisations. Similarly, the applications to the propagation over the focusing bathymetry of Whalin (1971) was a similar venue...

  11. Brain networks for exploration decisions utilizing distinct modeled information types during contextual learning.

    Science.gov (United States)

    Wang, Jane X; Voss, Joel L

    2014-06-04

    Exploration permits acquisition of the most relevant information during learning. However, the specific information needed, the influences of this information on decision making, and the relevant neural mechanisms remain poorly understood. We modeled distinct information types available during contextual association learning and used model-based fMRI in conjunction with manipulation of exploratory decision making to identify neural activity associated with information-based decisions. We identified hippocampal-prefrontal contributions to advantageous decisions based on immediately available novel information, distinct from striatal contributions to advantageous decisions based on the sum total available (accumulated) information. Furthermore, network-level interactions among these regions during exploratory decision making were related to learning success. These findings link strategic exploration decisions during learning to quantifiable information and advance understanding of adaptive behavior by identifying the distinct and interactive nature of brain-network contributions to decisions based on distinct information types.

  12. A Qualitative Analysis of The Bianchi Type IV Viscous Fluid Model

    CERN Document Server

    Kohli, Ikjyot Singh

    2012-01-01

    We are interested in formulating a viscous model of the universe based on The Bianchi Type IV algebra. We first begin by considering a congruence of fluid lines in spacetime, upon which, analyzing their propagation behaviour, we derive the famous Raychaudhuri equation, but, in the context of viscous fluids. We will then go through in great detail the topological and algebraic structure of a Bianchi Type IV algebra, by which we will derive the corresponding structure and constraint equations. From this, we will look at The Einstein field equations in the context of orthonormal frames, and derive the resulting dynamical equations: The Raychaudhuri Equation, generalized Friedmann equation, shear propagation equations, and a set of non-trivial constraint equations. We show that for cases in which the bulk viscous pressure is significantly larger than the shear viscosity, this cosmological model isotropizes asymptotically.

  13. Proposal of a risk model for vehicular traffic: A Boltzmann-type kinetic approach

    CERN Document Server

    Freguglia, Paolo

    2015-01-01

    This paper deals with a Boltzmann-type kinetic model describing the interplay between vehicle dynamics and safety aspects in vehicular traffic. Sticking to the idea that the macroscopic characteristics of traffic flow, including the distribution of the driving risk along a road, are ultimately generated by one-to-one interactions among drivers, the model links the personal (i.e., individual) risk to the changes of speeds of single vehicles and implements a probabilistic description of such microscopic interactions in a Boltzmann-type collisional operator. By means of suitable statistical moments of the kinetic distribution function, it is finally possible to recover macroscopic relationships between the average risk and the road congestion, which show an interesting and reasonable correlation with the well-known free and congested phases of the flow of vehicles.

  14. Evidence Feed Forward Hidden Markov Model: A New Type of Hidden Markov Model

    CERN Document Server

    DelRose, Michael; Frederick, Philip; 10.5121/ijaia.2011.2101

    2011-01-01

    The ability to predict the intentions of people based solely on their visual actions is a skill only performed by humans and animals. The intelligence of current computer algorithms has not reached this level of complexity, but there are several research efforts that are working towards it. With the number of classification algorithms available, it is hard to determine which algorithm works best for a particular situation. In classification of visual human intent data, Hidden Markov Models (HMM), and their variants, are leading candidates. The inability of HMMs to provide a probability in the observation to observation linkages is a big downfall in this classification technique. If a person is visually identifying an action of another person, they monitor patterns in the observations. By estimating the next observation, people have the ability to summarize the actions, and thus determine, with pretty good accuracy, the intention of the person performing the action. These visual cues and linkages are important...

  15. Stability of Fuzzy S^2 x S^2 x S^2 in IIB Type Matrix Models

    CERN Document Server

    Kaneko, H; Tomino, D

    2005-01-01

    We study the stability of fuzzy S^2 x S^2 x S^2 backgrounds in three different IIB type matrix models with respect to the change of the spins of each S^2 at the two loop level. We find that S^2 x S^2 x S^2 background is metastable and the effective action favors a single large S^2 in comparison to the remaining S^2 x S^2 in the models with Myers term. On the other hand, we find that a large S^2 x S^2 in comparison to the remaining S^2 is favored in IIB matrix model itself. We further study the stability of fuzzy S^2 x S^2 background in detail in IIB matrix model with respect to the scale factors of each S^2 as well. In this case, we find unstable directions which lower the effective action away from the most symmetric fuzzy S^2 x S^2 background.

  16. Exercise effects in a virtual type 1 diabetes patient: Using stochastic differential equations for model extension

    DEFF Research Database (Denmark)

    Duun-Henriksen, Anne Katrine; Schmidt, S.; Nørgaard, K.

    2013-01-01

    The use of virtual patients for in silico testing of control algorithms for an artificial pancreas is growing. It is an easy, fast and low-cost alternative to pre-clinical testing. To simulate the everyday life of a type 1 diabetes (T1D) patient a simulator must be able to take into account...... extension incorporating exercise effects on insulin and glucose dynamics. Our model is constructed as a stochastic state space model consisting of a set of stochastic differential equations (SDEs). In a stochastic state space model, the residual error is split into random measurement error...... on clinical data from a study including exercise bouts of 20 minutes performed on 12 T1D patients treated with continuous subcutaneous insulin infusion. The predictive abilities of the model are investigated. In conclusion, this study illustrates the advantages of using SDEs in the development of an extended...

  17. Modeling the effects of dust evolution on the SEDs of galaxies of different morphological type

    CERN Document Server

    Schurer, A; Silva, L; Pipino, A; Granato, G L; Matteucci, F; Maiolino, R

    2009-01-01

    We present photometric evolution models of galaxies, in which, in addition to the stellar component, the effects of an evolving dusty interstellar medium have been included with particular care. Starting from the work of Calura, Pipino & Matteucci (2008), in which chemical evolution models have been used to study the evolution of both the gas and dust components of the interstellar medium in the solar neighbourhood, elliptical and irregular galaxies, it has been possible to combine these models with a spectrophotometric stellar code that includes dust reprocessing (GRASIL) (Silva et al. 1998) to analyse the evolution of the spectral energy distributions (SED) of these galaxies. We test our models against observed SEDs both in the local universe and at high redshift and use them to predict how the percentage of reprocessed starlight evolves for each type of galaxy. The importance of following the dust evolution is investigated by comparing our results with those obtained by adopting simple assumptions to t...

  18. Selecting the "right" mouse model for metabolic syndrome and type 2 diabetes research.

    Science.gov (United States)

    Leiter, Edward H

    2009-01-01

    This is not a "Methods" chapter in the traditional sense. Rather, it is an essay designed to help address one of the most frequently asked questions by investigators about to embark on a study requiring an animal model of diabetes - what is the "right" model for the reader's specific research application. Because genetic heterogeneity and the requirement for complex gene-environment interaction characterize the various mouse models of Type 2 diabetes as well as the human disease manifestations, the readers may come to share the author's conclusion that more than one model is required if the investigator is interested in knowing how broadly effective a given compound with putative therapeutic efficacy might be.

  19. Time-Dependent Toroidal Compactification Proposals and the Bianchi Type I Model: Classical and Quantum Solutions

    Directory of Open Access Journals (Sweden)

    L. Toledo Sesma

    2016-01-01

    Full Text Available We construct an effective four-dimensional model by compactifying a ten-dimensional theory of gravity coupled with a real scalar dilaton field on a time-dependent torus. This approach is applied to anisotropic cosmological Bianchi type I model for which we study the classical coupling of the anisotropic scale factors with the two real scalar moduli produced by the compactification process. Under this approach, we present an isotropization mechanism for the Bianchi I cosmological model through the analysis of the ratio between the anisotropic parameters and the volume of the Universe which in general keeps constant or runs into zero for late times. We also find that the presence of extra dimensions in this model can accelerate the isotropization process depending on the momenta moduli values. Finally, we present some solutions to the corresponding Wheeler-DeWitt (WDW equation in the context of standard quantum cosmology.

  20. Modeling of a split type air conditioner with integrated water heater

    Energy Technology Data Exchange (ETDEWEB)

    Techarungpaisan, P.; Theerakulpisut, S.; Priprem, S. [Mechanical Engineering Department, Faculty of Engineering, Khon Kaen University, 123 Mittrapab Rd., Muang, Khon Kaen 40002 (Thailand)

    2007-04-15

    This paper presents a steady state simulation model to predict the performance of a small split type air conditioner with integrated water heater. The mathematical model consists of submodels of system components such as evaporator, condenser, compressor, capillary tube, receiver and water heater. These submodels were built based on fundamental principles of heat transfer, thermodynamics, fluid mechanics, empirical relationships and manufacturer's data as necessary. The model was coded into a simulation program and used to predict system parameters of interest such as hot water temperature, condenser exit air temperature, evaporator exit air temperature, mass flow rate of refrigerant, heat rejection in the condenser and cooling capacity of the system. The simulation results were compared with experimental data obtained from an experimental rig built for validating the mathematical model. It was found that the experimental and simulation results are in good agreement. (author)

  1. Study of Mechanical Properties of Wool Type Fabrics using ANCOVA Regression Model

    Science.gov (United States)

    Hristian, L.; Ostafe, M. M.; Manea, L. R.; Apostol, L. L.

    2017-06-01

    The work has achieved a study on the variation of tensile strength for the four groups of wool fabric type, depending on the fiber composition, the tensile strength of the warp yarns and the weft yarns technological density using ANCOVA regression model. ANCOVA checks the correlation between a dependent variable and the covariate independent variables and removes the variability from the dependent variable that can be accounted for by the covariates. Analysis of covariance models combines analysis of variance with regression analysis techniques. Regarding design, ANCOVA models explain the dependent variable by combining categorical (qualitative) independent variables with continuous (quantitative) variables. There are special extensions to ANCOVA calculations to estimate parameters for both categorical and continuous variables. However ANCOVA models can also be calculated using multiple regression analysis using a design matrix with a mix of dummy-coded qualitative and quantitative variables.

  2. Positivity of Lyapunov exponents for Anderson-type models on two coupled strings

    Directory of Open Access Journals (Sweden)

    Hakim Boumaza

    2007-03-01

    Full Text Available We study two models of Anderson-type random operators on two deterministically coupled continuous strings. Each model is associated with independent, identically distributed four-by-four symplectic transfer matrices, which describe the asymptotics of solutions. In each case we use a criterion by Gol'dsheid and Margulis (i.e. Zariski denseness of the group generated by the transfer matrices in the group of symplectic matrices to prove positivity of both leading Lyapunov exponents for most energies. In each case this implies almost sure absence of absolutely continuous spectrum (at all energies in the first model and for sufficiently large energies in the second model. The methods used allow for singularly distributed random parameters, including Bernoulli distributions.

  3. Bianchi type-VIh string cloud cosmological models with bulk viscosity

    Science.gov (United States)

    Tripathy, Sunil K.; Behera, Dipanjali

    2010-11-01

    String cloud cosmological models are studied using spatially homogeneous and anisotropic Bianchi type VIh metric in the frame work of general relativity. The field equations are solved for massive string cloud in presence of bulk viscosity. A general linear equation of state of the cosmic string tension density with the proper energy density of the universe is considered. The physical and kinematical properties of the models have been discussed in detail and the limits of the anisotropic parameter responsible for different phases of the universe are explored.

  4. Torsional fatigue model for limitorque type SMB/SB/SBD actuators for motor-operated valves

    Energy Technology Data Exchange (ETDEWEB)

    Somogyi, D.; Alvarez, P.D.; Kalsi, M.S. [Kalsi Engineering, Inc., Sugar Land, TX (United States)

    1996-12-01

    Kalsi Engineering, Inc. has recently developed a computer program to predict the torsional fatigue life of Limitorque Type SMB/SB/SBD actuators for motor-operated valves under given loading levels, including those that exceed the ratings. The development effort was an outgrowth of the {open_quote}Thrust Rating Increase{close_quote} test program. The fatigue model computes all pertinent stress components and their variations as a function of the loading ramp. The cumulative damage and fatigue life due to stress cycling is computed by use of a modification of Miner`s rule. Model predictions were validated against actual cyclic loading test results.

  5. Non-equilibrium Dynamics for a Widom-Rowlinson Type Model with Mutations

    Science.gov (United States)

    Friesen, Martin

    2017-01-01

    A dynamical version of the Widom-Rowlinson model in the continuum is considered. The dynamics is modelled by a spatial two-component birth-and-death Glauber process where particles, in addition, are allowed to change their type with density dependent rates. An evolution of states is constructed in terms of correlation function evolution in a certain Ruelle space. It is shown that such evolution provides the unique weak solution to the associated Fokker-Planck equation. Existence of a unique invariant measure and ergodicity with exponential rate is established. Vlasov scaling is performed and the chaos preservation property is shown.

  6. LRS Bianchi type-I string cosmological model in f(R, T) gravity

    Energy Technology Data Exchange (ETDEWEB)

    Sahoo, Pradyumn [Department of Mathematics, Birla Institute of Technology and Science-Pilani, Hyderabad (India)

    2016-04-15

    In this study the locally rotationally symmetric (LRS) Bianchi type-I (BI) cosmological model has been investigated in the presence of one dimensional cosmic strings in f(R, T) gravity. The exact solutions of the field equations are obtained through the use of constant deceleration parameter [1] and the scalar expansion is proportional to the shear scalar. Considering the accelerating nature of the universe in the present epoch, the physical behavior of the model has been discussed. (copyright 2015 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  7. The Dynamics of Epidemic Model with Two Types of Infectious Diseases and Vertical Transmission

    Directory of Open Access Journals (Sweden)

    Raid Kamel Naji

    2016-01-01

    Full Text Available An epidemic model that describes the dynamics of the spread of infectious diseases is proposed. Two different types of infectious diseases that spread through both horizontal and vertical transmission in the host population are considered. The basic reproduction number R0 is determined. The local and the global stability of all possible equilibrium points are achieved. The local bifurcation analysis and Hopf bifurcation analysis for the four-dimensional epidemic model are studied. Numerical simulations are used to confirm our obtained analytical results.

  8. Dynamics of a Lotka-Volterra type model with applications to marine phage population dynamics

    Energy Technology Data Exchange (ETDEWEB)

    Gavin, C [School of Mathematical Sciences University College Cork, Cork (Ireland); Pokrovskii, A [School of Mathematical Sciences University College Cork, Cork (Ireland); Prentice, M [Department of Microbiology University College Cork, Cork (Ireland); Sobolev, V [Department of Differential Equations and Control Theory Samara State University, Akademika Pavlova Street, 1, 443011 (Russian Federation)

    2006-12-01

    The famous Lotka-Volterra equations play a fundamental role in the mathematical modeling of various ecological and chemical systems. A new modification of these equations has been recently suggested to model the structure of marine phage populations, which are the most abundant biological entities in the biosphere. The purpose of the paper is: (i) to make some methodical remarks concerning this modification; (ii) to discuss new types of canards which arise naturally in this context; (iii) to present results of some numerical experiments.

  9. Multiple reflection-asymmetric type band structures in $^{220}Th$ and dinuclear model

    CERN Document Server

    Shneidman, T M; Antonenko, N V; Jolos, R V; Scheid, W

    2010-01-01

    The negative parity bands in $^{220}$Th are analyzed within the dinuclear system model which was previously used for describing the alternating-parity bands in deformed actinides. The model is based on the assumption that cluster type shapes are produced by the motion of nuclear system in the mass-asymmetry coordinate. To describe the reflection-asymmetric collective modes characterized by nonzero values of $K$, the intrinsic excitations of clusters are taken into account. The angular momentum dependence of the parity splitting and the staggering behavior of the $B(E1)/B(E2)$ ratios as functions of angular momentum are explained.

  10. Modeling and Optimization of M/G/1-Type Queueing Networks: An Efficient Sensitivity Analysis Approach

    Directory of Open Access Journals (Sweden)

    Liang Tang

    2010-01-01

    Full Text Available A mathematical model for M/G/1-type queueing networks with multiple user applications and limited resources is established. The goal is to develop a dynamic distributed algorithm for this model, which supports all data traffic as efficiently as possible and makes optimally fair decisions about how to minimize the network performance cost. An online policy gradient optimization algorithm based on a single sample path is provided to avoid suffering from a “curse of dimensionality”. The asymptotic convergence properties of this algorithm are proved. Numerical examples provide valuable insights for bridging mathematical theory with engineering practice.

  11. A consensus model for group decision making under interval type-2 fuzzy environment

    Institute of Scientific and Technical Information of China (English)

    Xiao-xiong ZHANG; Bing-feng GE; Yue-jin TAN

    2016-01-01

    We propose a new consensus model for group decision making (GDM) problems, using an interval type-2 fuzzy environment. In our model, experts are asked to express their preferences using linguistic terms characterized by interval type-2 fuzzy sets (IT2 FSs), because these can provide decision makers with greater freedom to express the vagueness in real-life situa-tions. Consensus and proximity measures based on the arithmetic operations of IT2 FSs are used simultaneously to guide the decision-making process. The majority of previous studies have taken into account only the importance of the experts in the aggregation process, which may give unreasonable results. Thus, we propose a new feedback mechanism that generates different advice strategies for experts according to their levels of importance. In general, experts with a lower level of importance require a larger number of suggestions to change their initial preferences. Finally, we investigate a numerical example and execute com-parable models and ours, to demonstrate the performance of our proposed model. The results indicate that the proposed model provides greater insight into the GDM process.

  12. [THE MODEL OF NEUROVASCULAR UNIT IN VITRO CONSISTING OF THREE CELLS TYPES].

    Science.gov (United States)

    Khilazheva, E D; Boytsova, E B; Pozhilenkova, E A; Solonchuk, Yu R; Salmina, A B

    2015-01-01

    There are many ways to model blood brain barrier and neurovascular unit in vitro. All existing models have their disadvantages, advantages and some peculiarities of preparation and usage. We obtained the three-cells neurovascular unit model in vitro using progenitor cells isolated from the rat embryos brain (Wistar, 14-16 d). After withdrawal of the progenitor cells the neurospheres were cultured with subsequent differentiation into astrocytes and neurons. Endothelial cells were isolated from embryonic brain too. During the differentiation of progenitor cells the astrocytes monolayer formation occurs after 7-9 d, neurons monolayer--after 10-14 d, endothelial cells monolayer--after 7 d. Our protocol for simultaneous isolation and cultivation of neurons, astrocytes and endothelial cells reduces the time needed to obtain neurovascular unit model in vitro, consisting of three cells types and reduce the number of animals used. It is also important to note the cerebral origin of all cell types, which is also an advantage of our model in vitro.

  13. Globular clusters kinematics and dynamical models of the massive early-type galaxy NGC 1399

    Science.gov (United States)

    Samurović, S.

    2016-06-01

    We analyze the dynamical models of the massive early-type galaxy NGC 1399, the central galaxy of the Fornax cluster. We use the sample of 790 globular clusters as tracers of gravitational potential and we first extract the kinematics, which is then dynamically modeled. We find that the velocity dispersion remains high and approximately constant throughout the whole galaxy and that the departures from the Gaussian distribution of the orbits are not large. We use the spherical Jeans equation in both Newtonian and MOND approaches, assuming three cases of orbital anisotropies: we study isotropic, tangentially and radially anisotropic models in order to establish the best-fitting values of the mass-to-light ratios. We found that in the Newtonian approximation a significant amount of dark matter is needed and that Navarro-Frenk-White (NFW) model with a dark halo provides a satisfactory description of the kinematics of NGC 1399. We tested three MOND models (standard, simple and toy) and found that none of them can provide a fit of the velocity dispersion profile without the inclusion of dark matter. Finally, using our findings, we placed the galaxy NGC 1399 within the context of other observed early-type galaxies and discuss its location among them.

  14. Dynamic analysis and control PID path of a model type gantry crane

    Science.gov (United States)

    Ospina-Henao, P. A.; López-Suspes, Framsol

    2017-06-01

    This paper presents an alternate form for the dynamic modelling of a mechanical system that simulates in real life a gantry crane type, using Euler’s classical mechanics and Lagrange formalism, which allows find the equations of motion that our model describe. Moreover, it has a basic model design system using the SolidWorks software, based on the material and dimensions of the model provides some physical variables necessary for modelling. In order to verify the theoretical results obtained, a contrast was made between solutions obtained by simulation in SimMechanics-Matlab and Euler-Lagrange equations system, has been solved through Matlab libraries for solving equation’s systems of the type and order obtained. The force is determined, but not as exerted by the spring, as this will be the control variable. The objective is to bring the mass of the pendulum from one point to another with a specified distance without the oscillation from it, so that, the answer is overdamped. This article includes an analysis of PID control in which the equations of motion of Euler-Lagrange are rewritten in the state space, once there, they were implemented in Simulink to get the natural response of the system to a step input in F and then draw the desired trajectories.

  15. Distribution of the largest event in the critical epidemic-type aftershock-sequence model.

    Science.gov (United States)

    Vere-Jones, David; Zhuang, Jiancang

    2008-10-01

    This Brief Report corrects and extends the results of Zhuang and Ogata [Phys. Rev. E 73, 046134 (2006)] on the asymptotic behavior of the largest event in the epidemic-type aftershock-sequence model for earthquake occurrence. We show that, in the special case that the underlying branching process is critical, there exists a previously unnoticed mode of behavior, which occurs when the expected family size grows relatively slowly.

  16. Anisotropic Dark Energy Bianchi Type III Cosmological Models in Brans Dicke Theory of Gravity

    CERN Document Server

    Shamir, M Farasat; 10.1139/P2012-007

    2012-01-01

    The main purpose of this paper is to explore the solutions of Bianchi type $III$ cosmological model in Brans Dicke theory of gravity in the background of anisotropic dark energy. We use the assumption of constant deceleration parameter and power law relation between scalar field $\\phi$ and scale factor $a$ to find the solutions. The physical behavior of the solutions has been discussed using some physical quantities.

  17. Flow and mixing of liquid steel in multi-strand tundish delta type – physical modelling

    Directory of Open Access Journals (Sweden)

    T. Merder

    2015-01-01

    Full Text Available The article presents the results of liquid steel flow and mixing in tundish when applying different equipment to modernize the tundish working zone. The six-strand continuous casting tundish of a trough-type was studied. Such tundish is an object with geometry adjusted to the conditions of particular CC machine, which is installed in one of a polish steel plant. The problems suggested in research were solved basing on physical model experiment.

  18. Dynamics of a three species food chain model with Crowley-Martin type functional response

    Energy Technology Data Exchange (ETDEWEB)

    Upadhyay, Ranjit Kumar [Department of Applied Mathematics, Indian School of Mines University, Dhanbad, Jharkhand 826 004 (India)], E-mail: ranjit_ism@yahoo.com; Naji, Raid Kamel [Department of Mathematics, College of Science, University of Baghdad (Iraq)], E-mail: rknaji@gmail.com

    2009-11-15

    In this paper, a three species food chain model, consisting of a hybrid type of prey-dependent and predator-dependent functional responses, is investigated analytically as well as numerically. The local and global stability analysis is carried out. The persistence conditions are established. Bifurcation diagrams are obtained for biologically feasible parameters. The results show that the system exhibits rich complexity features such as stable, periodic and chaotic dynamics.

  19. Distribution of the largest event in the critical epidemic-type aftershock-sequence model

    Science.gov (United States)

    Vere-Jones, David; Zhuang, Jiancang

    2008-10-01

    This Brief Report corrects and extends the results of Zhuang and Ogata [Phys. Rev. E 73, 046134 (2006)] on the asymptotic behavior of the largest event in the epidemic-type aftershock-sequence model for earthquake occurrence. We show that, in the special case that the underlying branching process is critical, there exists a previously unnoticed mode of behavior, which occurs when the expected family size grows relatively slowly.

  20. Van der Waals Type Model and Structure in π-p Elastic Scattering at High Energies

    Science.gov (United States)

    Aleem, F.

    1982-10-01

    The most recent measurement of the angular distribution for π-p elastic scattering at pL =50 and 200 GeV/c which show a structure near -t ≈ 4(GeV/c)2, with squared four momentum transfer -t extended to 10(GeV/c)2, and the total cross section data for 50 ≤ pL ≤ 370 GeV/c have been simultaneously explained by using Van der Waal's type model.

  1. Locally Rotationally Symmetric Bianchi Type-I Model with Time Varying (A) Term

    Institute of Scientific and Technical Information of China (English)

    R.K.Tiwari; Navin Kumar Jha

    2009-01-01

    We investigate the locally rotationally symmetric (LRS) Bianchi type-Ⅰ cosmological model for stiff matter and a vacuum solution with a cosmological term proportional to R~(-m) (R is the scale factor and m is a positive constant).The cosmological term decreases with time.We obtain that for both the cases the present universe is accelerating with a large fraction of cosmological density in the form of a cosmological term.

  2. On the asymptotic behavior of a boltzmann-type price formation model

    KAUST Repository

    Burger, Martin

    2014-01-01

    In this paper we study the asymptotic behavior of a Boltzmann-type price formation model, which describes the trading dynamics in a financial market. In many of these markets trading happens at high frequencies and low transaction costs. This observation motivates the study of the limit as the number of transactions k tends to infinity, the transaction cost a to zero and ka=const. Furthermore we illustrate the price dynamics with numerical simulations © 2014 International Press.

  3. Analysis of Types of Oscillations in Goodwin's Model of Business Cycle

    Science.gov (United States)

    Antonova, A. O.; Reznik, S. N.; Todorov, M. D.

    2010-11-01

    Types of solutions of the Goodwin business cycle model with the fixed investment time lag have been numerically studied. It is shown that the long-periodic Goodwin's oscillations are excited by the independent investment A in case A exceeds a threshold. If A falls below the threshold, then there are only sawtooth oscillations with a period equal to the investment time lag. Near the threshold, the time behavior of the income is irregular.

  4. 3D climate modeling of Earth-like extrasolar planets orbiting different types of host stars

    Science.gov (United States)

    Godolt, M.; Grenfell, J. L.; Hamann-Reinus, A.; Kitzmann, D.; Kunze, M.; Langematz, U.; von Paris, P.; Patzer, A. B. C.; Rauer, H.; Stracke, B.

    2015-06-01

    The potential habitability of a terrestrial planet is usually defined by the possible existence of liquid water on its surface, since life as we know it needs liquid water at least during a part of its life cycle. The potential presence of liquid water on a planetary surface depends on many factors such as, most importantly, surface temperatures. The properties of the planetary atmosphere and its interaction with the radiative energy provided by the planet's host star are thereby of decisive importance. In this study we investigate the influence of different main-sequence stars (F, G, and K-type stars) upon the climate of Earth-like extrasolar planets and their potential habitability by applying a state-of-the-art three-dimensional (3D) Earth climate model accounting for local and dynamical processes. The calculations have been performed for planets with Earth-like atmospheres at orbital distances (and corresponding orbital periods) where the total amount of energy received from the various host stars equals the solar constant. In contrast to previous 3D modeling studies, we include the effect of ozone radiative heating upon the vertical temperature structure of the atmospheres. The global orbital mean results obtained have been compared to those of a one-dimensional (1D) radiative convective climate model to investigate the approximation of global mean 3D results by those of 1D models. The different stellar spectral energy distributions lead to different surface temperatures and due to ozone heating to very different vertical temperature structures. As previous 1D studies we find higher surface temperatures for the Earth-like planet around the K-type star, and lower temperatures for the planet around the F-type star compared to an Earth-like planet around the Sun. However, this effect is more pronounced in the 3D model results than in the 1D model because the 3D model accounts for feedback processes such as the ice-albedo and the water vapor feedback. Whether the

  5. Modeling of locally self-similar processes using multifractional Brownian motion of Riemann-Liouville type.

    Science.gov (United States)

    Muniandy, S V; Lim, S C

    2001-04-01

    Fractional Brownian motion (FBM) is widely used in the modeling of phenomena with power spectral density of power-law type. However, FBM has its limitation since it can only describe phenomena with monofractal structure or a uniform degree of irregularity characterized by the constant Holder exponent. For more realistic modeling, it is necessary to take into consideration the local variation of irregularity, with the Holder exponent allowed to vary with time (or space). One way to achieve such a generalization is to extend the standard FBM to multifractional Brownian motion (MBM) indexed by a Holder exponent that is a function of time. This paper proposes an alternative generalization to MBM based on the FBM defined by the Riemann-Liouville type of fractional integral. The local properties of the Riemann-Liouville MBM (RLMBM) are studied and they are found to be similar to that of the standard MBM. A numerical scheme to simulate the locally self-similar sample paths of the RLMBM for various types of time-varying Holder exponents is given. The local scaling exponents are estimated based on the local growth of the variance and the wavelet scalogram methods. Finally, an example of the possible applications of RLMBM in the modeling of multifractal time series is illustrated.

  6. Monte Carlo simulations for a Lotka-type model with reactant surface diffusion and interactions.

    Science.gov (United States)

    Zvejnieks, G; Kuzovkov, V N

    2001-05-01

    The standard Lotka-type model, which was introduced for the first time by Mai et al. [J. Phys. A 30, 4171 (1997)] for a simplified description of autocatalytic surface reactions, is generalized here for a case of mobile and energetically interacting reactants. The mathematical formalism is proposed for determining the dependence of transition rates on the interaction energy (and temperature) for the general mathematical model, and the Lotka-type model, in particular. By means of Monte Carlo computer simulations, we have studied the impact of diffusion (with and without energetic interactions between reactants) on oscillatory properties of the A+B-->2B reaction. The diffusion leads to a desynchronization of oscillations and a subsequent decrease of oscillation amplitude. The energetic interaction between reactants has a dual effect depending on the type of mobile reactants. In the limiting case of mobile reactants B the repulsion results in a decrease of amplitudes. However, these amplitudes increase if reactants A are mobile and repulse each other. A simplified interpretation of the obtained results is given.

  7. Modeling the competition between antenna size mutant and wild type microalgae in outdoor mass culture.

    Science.gov (United States)

    de Mooij, Tim; Schediwy, Kira; Wijffels, René H; Janssen, Marcel

    2016-12-20

    Under high light conditions, microalgae are oversaturated with light which significantly reduces the light use efficiency. Microalgae with a reduced pigment content, antenna size mutants, have been proposed as a potential solution to increase the light use efficiency. The goal of this study was to investigate the competition between antenna size mutants and wild type microalgae in mass cultures. Using a kinetic model and literature-derived experimental data from wild type Chlorella sorokiniana, the productivity and competition of wild type cells and antenna size mutants were simulated. Cultivation was simulated in an outdoor microalgal raceway pond production system which was assumed to be limited by light only. Light conditions were based on a Mediterranean location (Tunisia) and a more temperate location (the Netherlands). Several wild type contamination levels were simulated in each mutant culture separately to predict the effect on the productivity over the cultivation time of a hypothetical summer season of 100days. The simulations demonstrate a good potential of antenna size reduction to increase the biomass productivity of microalgal cultures. However, it was also found that after a contamination with wild type cells the mutant cultures will be rapidly overgrown resulting in productivity loss.

  8. Tests of Parameters Instability: Theoretical Study and Empirical Applications on Two Types of Models (ARMA Model and Market Model

    Directory of Open Access Journals (Sweden)

    Sahbi FARHANI

    2012-01-01

    Full Text Available This paper considers tests of parameters instability and structural change with known, unknown or multiple breakpoints. The results apply to a wide class of parametric models that are suitable for estimation by strong rules for detecting the number of breaks in a time series. For that, we use Chow, CUSUM, CUSUM of squares, Wald, likelihood ratio and Lagrange multiplier tests. Each test implicitly uses an estimate of a change point. We conclude with an empirical analysis on two different models (ARMA model and simple linear regression model.

  9. Assessing cognitive alignment in different types of dialog by means of a network model.

    Science.gov (United States)

    Mehler, Alexander; Lücking, Andy; Menke, Peter

    2012-08-01

    We present a network model of dialog lexica, called TiTAN (Two-layer Time-Aligned Network) series. TiTAN series capture the formation and structure of dialog lexica in terms of serialized graph representations. The dynamic update of TiTAN series is driven by the dialog-inherent timing of turn-taking. The model provides a link between neural, connectionist underpinnings of dialog lexica on the one hand and observable symbolic behavior on the other. On the neural side, priming and spreading activation are modeled in terms of TiTAN networking. On the symbolic side, TiTAN series account for cognitive alignment in terms of the structural coupling of the linguistic representations of dialog partners. This structural stance allows us to apply TiTAN in machine learning of data of dialogical alignment. In previous studies, it has been shown that aligned dialogs can be distinguished from non-aligned ones by means of TiTAN -based modeling. Now, we simultaneously apply this model to two types of dialog: task-oriented, experimentally controlled dialogs on the one hand and more spontaneous, direction giving dialogs on the other. We ask whether it is possible to separate aligned dialogs from non-aligned ones in a type-crossing way. Starting from a recent experiment (Mehler, Lücking, & Menke, 2011a), we show that such a type-crossing classification is indeed possible. This hints at a structural fingerprint left by alignment in networks of linguistic items that are routinely co-activated during conversation.

  10. Sensitivities of the hydrologic cycle to model physics, grid resolution, and ocean type in the aquaplanet Community Atmosphere Model

    Science.gov (United States)

    Benedict, James J.; Medeiros, Brian; Clement, Amy C.; Pendergrass, Angeline G.

    2017-06-01

    Precipitation distributions and extremes play a fundamental role in shaping Earth's climate and yet are poorly represented in many global climate models. Here, a suite of idealized Community Atmosphere Model (CAM) aquaplanet simulations is examined to assess the aquaplanet's ability to reproduce hydroclimate statistics of real-Earth configurations and to investigate sensitivities of precipitation distributions and extremes to model physics, horizontal grid resolution, and ocean type. Little difference in precipitation statistics is found between aquaplanets using time-constant sea-surface temperatures and those implementing a slab ocean model with a 50 m mixed-layer depth. In contrast, CAM version 5.3 (CAM5.3) produces more time mean, zonally averaged precipitation than CAM version 4 (CAM4), while CAM4 generates significantly larger precipitation variance and frequencies of extremely intense precipitation events. The largest model configuration-based precipitation sensitivities relate to choice of horizontal grid resolution in the selected range 1-2°. Refining grid resolution has significant physics-dependent effects on tropical precipitation: for CAM4, time mean zonal mean precipitation increases along the Equator and the intertropical convergence zone (ITCZ) narrows, while for CAM5.3 precipitation decreases along the Equator and the twin branches of the ITCZ shift poleward. Increased grid resolution also reduces light precipitation frequencies and enhances extreme precipitation for both CAM4 and CAM5.3 resulting in better alignment with observational estimates. A discussion of the potential implications these hydrologic cycle sensitivities have on the interpretation of precipitation statistics in future climate projections is also presented.Plain Language SummaryPrecipitation plays a fundamental role in shaping Earth's climate. Global climate models predict the average precipitation reasonably well but often struggle to accurately represent how often it

  11. Effects of Spironolactone and Losartan on Diabetic Nephropathy in a Type 2 Diabetic Rat Model

    Directory of Open Access Journals (Sweden)

    Mi Young Lee

    2011-04-01

    Full Text Available BackgroundWhile there is an evidence that the anti-inflammatory properties of spironolactone can attenuate proteinuria in type 2 diabetes, its effects on vascular endothelial growth factor (VEGF expression in diabetic nephropathy have not been clearly defined. In this study, we examined the effects of spironolactone, losartan, and a combination of these two drugs on albuminuria, renal VEGF expression, and inflammatory and oxidative stress markers in a type 2 diabetic rat model.MethodsThirty-three Otsuka-Long-Evans-Tokushima-Fatty (OLETF rats were divided into four groups and treated with different medication regimens from weeks 25 to 50; OLETF diabetic controls (n=5, spironolactone-treated (n=10, losartan-treated (n=9, and combination of spironolactone- and losartan-treated (n=9.ResultsAt week 50, the albumin-to-creatinine ratio was significantly decreased in the losartan and combination groups compared to the control OLETF group. No decrease was detected in the spironolactone group. There was a significant reduction in renal VEGF, transforming growth factor (TGF-β, and type IV collagen mRNA levels in the spironolactone- and combination regimen-treated groups. Twenty-four hour urine monocyte chemotactic protein-1 levels were comparable in all four groups but did show a decreasing trend in the losartan and combination regimen groups. Twenty-four hour urine malondialdehyde levels were significantly decreased in the spironolactone- and combination regimen-treated groups.ConclusionThese results suggest that losartan alone and a combined regimen of spironolactone and losartan could ameliorate albuninuria by reducing renal VEGF expression. Also, simultaneous treatment with spironolactone and losartan may have protective effects against diabetic nephropathy by decreasing TGF-β and type IV collagen expression and by reducing oxidative stress in a type 2 diabetic rat model.

  12. Mathematical Modeling of Dual Layer Shell Type Recuperation System for Biogas Dehumidification

    Science.gov (United States)

    Gendelis, S.; Timuhins, A.; Laizans, A.; Bandeniece, L.

    2015-12-01

    The main aim of the current paper is to create a mathematical model for dual layer shell type recuperation system, which allows reducing the heat losses from the biomass digester and water amount in the biogas without any additional mechanical or chemical components. The idea of this system is to reduce the temperature of the outflowing gas by creating two-layered counter-flow heat exchanger around the walls of biogas digester, thus increasing a thermal resistance and the gas temperature, resulting in a condensation on a colder surface. Complex mathematical model, including surface condensation, is developed for this type of biogas dehumidifier and the parameter study is carried out for a wide range of parameters. The model is reduced to 1D case to make numerical calculations faster. It is shown that latent heat of condensation is very important for the total heat balance and the condensation rate is highly dependent on insulation between layers and outside temperature. Modelling results allow finding optimal geometrical parameters for the known gas flow and predicting the condensation rate for different system setups and seasons.

  13. Accelerating dark energy models with anisotropic fluid in Bianchi type-$VI_{0}$ space-time

    CERN Document Server

    Pradhan, Anirudh

    2012-01-01

    Motivated by the increasing evidence for the need of a geometry that resembles Bianchi morphology to explain the observed anisotropy in the WMAP data, we have discussed some features of the Bianchi type-$VI_{0}$ universes in the presence of a fluid that wields an anisotropic equation of state (EoS) parameter in general relativity. We present two accelerating dark energy (DE) models with an anisotropic fluid in Bianchi type-$VI_{0}$ space-time. To prevail the deterministic solution we choose the scale factor $a(t) = \\sqrt{t^{n}e^{t}}$, which yields a time-dependent deceleration parameter (DP), representing a class of models which generate a transition of the universe from the early decelerating phase to the recent accelerating phase. Under the suitable condition, the anisotropic models approach to isotropic scenario. The EoS for dark energy $\\omega$ is found to be time-dependent and its existing range for derived models is in good agreement with the recent observations of SNe Ia data (Knop et al. 2003), SNe Ia...

  14. Model-based clustering for assessing the prognostic value of imaging biomarkers and mixed type tests.

    Science.gov (United States)

    Wang, Zheyu; Sebestyen, Krisztian; Monsell, Sarah E

    2017-09-01

    A model-based clustering method is proposed to address two research aims in Alzheimer's disease (AD): to evaluate the accuracy of imaging biomarkers in AD prognosis, and to integrate biomarker information and standard clinical test results into the diagnoses. One challenge in such biomarker studies is that it is often desired or necessary to conduct the evaluation without relying on clinical diagnoses or some other standard references. This is because (1) biomarkers may provide prognostic information long before any standard reference can be acquired; (2) these references are often based on or provide unfair advantage to standard tests. Therefore, they can mask the prognostic value of a useful biomarker, especially when the biomarker is much more accurate than the standard tests. In addition, the biomarkers and existing tests may be of mixed type and vastly different distributions. A model-based clustering method based on finite mixture modeling framework is introduced. The model allows for the inclusion of mixed typed manifest variables with possible differential covariates to evaluate the prognostic value of biomarkers in addition to standard tests without relying on potentially inaccurate reference diagnoses. Maximum likelihood parameter estimation is carried out via the EM algorithm. Accuracy measures and the ROC curves of the biomarkers are derived subsequently. Finally, the method is illustrated with a real example in AD.

  15. Effect of Implementing Ecosystem Functional Type Data in a Mesoscale Climate Model

    Institute of Scientific and Technical Information of China (English)

    Seung-Jae LEE; E.Hugo BERBERY; Domingo ALCARAZ-SEGURA

    2013-01-01

    In this paper,we introduce a new concept of land-surface state representation for southern South America,which is based on "functional" attributes of vegetation,and implement a new land-cover (Ecosystem Functional Type,hereafter EFT) dataset in the Weather and Research Forecasting (WRF) model.We found that the EFT data enabled us to deal with functional attributes of vegetation and time-variant features more easily than the default land-cover data in the WRF.In order to explore the usefulness of the EFT data in simulations of surface and atmospheric variables,numerical simulations of the WRF model,using both the US Geological Survey (USGS) and the EFT data,were conducted over the La Plata Basin in South America for the austral spring of 1998 and compared with observations.Results showed that the model simulations were sensitive to the lower boundary conditions and that the use of the EFT data improved the climate simulation of 2-m temperature and precipitation,implying the need for this type of information to be included in numerical climate models.

  16. Image guided personalization of reaction-diffusion type tumor growth models using modified anisotropic eikonal equations.

    Science.gov (United States)

    Konukoglu, Ender; Clatz, Olivier; Menze, Bjoern H; Stieltjes, Bram; Weber, Marc-André; Mandonnet, Emmanuel; Delingette, Hervé; Ayache, Nicholas

    2010-01-01

    Reaction-diffusion based tumor growth models have been widely used in the literature for modeling the growth of brain gliomas. Lately, recent models have started integrating medical images in their formulation. Including different tissue types, geometry of the brain and the directions of white matter fiber tracts improved the spatial accuracy of reaction-diffusion models. The adaptation of the general model to the specific patient cases on the other hand has not been studied thoroughly yet. In this paper, we address this adaptation. We propose a parameter estimation method for reaction-diffusion tumor growth models using time series of medical images. This method estimates the patient specific parameters of the model using the images of the patient taken at successive time instances. The proposed method formulates the evolution of the tumor delineation visible in the images based on the reaction-diffusion dynamics; therefore, it remains consistent with the information available. We perform thorough analysis of the method using synthetic tumors and show important couplings between parameters of the reaction-diffusion model. We show that several parameters can be uniquely identified in the case of fixing one parameter, namely the proliferation rate of tumor cells. Moreover, regardless of the value the proliferation rate is fixed to, the speed of growth of the tumor can be estimated in terms of the model parameters with accuracy. We also show that using the model-based speed, we can simulate the evolution of the tumor for the specific patient case. Finally, we apply our method to two real cases and show promising preliminary results.

  17. Animal models of catheter-induced intimal hyperplasia in type 1 and type 2 diabetes and the effects of pharmacologic intervention.

    Science.gov (United States)

    McNamara, D B; Murthy, S N; Fonseca, A N; Desouza, C V; Kadowitz, P J; Fonseca, V A

    2009-01-01

    Diabetes is a complex disorder characterized by impaired insulin formation, release or action (insulin resistance), elevated blood glucose, and multiple long-term complications. It is a common endocrine disorder of humans and is associated with abnormalities of carbohydrate and lipid metabolism. There are two forms of diabetes, classified as type 1 and type 2. In type 1 diabetes, hyperglycemia is due to an absolute lack of insulin, whereas in type 2 diabetes, hyperglycemia is due to a relative lack of insulin and insulin resistance. More than 90% of people with diabetes have type 2 with varied degrees of insulin resistance. Insulin resistance is often associated with impaired insulin secretion, and hyperglycemia is a common feature in both types of diabetes, but failure to make a distinction between the types of diabetes in different animal models has led to confusion in the literature. This is particularly true in relation to cardiovascular disease in the presence of diabetes and especially the response to vascular injury, in which there are major differences between the two types of diabetes. Animal models do not completely mimic the clinical disease seen in humans. Animal models are at best analogies of the pathologic process they are designed to represent. The focus of this review is an analysis of intimal hyperplasia following catheter-induced vascular injury, including factors that may complicate comparisons between different animal models or between in vitro and in vivo studies. We examine the variables, pitfalls, and caveats that follow from the manner of induction of the injury and the diabetic state of the animal. The efficacy of selected antidiabetic drugs in inhibiting the development of the hyperplastic response is also discussed.

  18. $h\\rightarrow Z\\gamma$ in Type-II seesaw neutrino model

    CERN Document Server

    Chen, Chian-Shu; Huang, Da; Tsai, Lu-Hsing

    2013-01-01

    We study the Higgs decay channel of $h\\rightarrow Z\\gamma$ in the type-II seesaw neutrino model. In most of the allowed parameter space in the model, the new contribution to $h\\rightarrow Z\\gamma$ is correlated with that to $h\\rightarrow\\gamma\\gamma$. If the current $2\\sigma$ excess of the $h\\rightarrow \\gamma\\gamma$ rate measured by the LHC persists, the $h\\rightarrow Z\\gamma$ rate should be also larger than the corresponding standard model prediction. We demonstrate that the anti-correlation between $h\\rightarrow\\gamma\\gamma$ and $h\\rightarrow Z\\gamma$ only exists in some special region.

  19. Bianchi type-V dark energy model with varying EoS parameter

    CERN Document Server

    Saha, Bijan

    2012-01-01

    Within the scope of an anisotropic Bianchi type-V cosmological model we have studied the evolution of the universe. The assumption of a diagonal energy-momentum tensor leads to some severe restriction on the metric functions, which on its part imposes restriction on the components of the energy momentum tensor. This model allows anisotropic matter distribution. Further using the proportionality condition that relates the shear scalar $(\\sigma)$ in the model is proportional to expansion scalar $(\\vartheta)$ and the variation law of Hubble parameter, connecting Hubble parameter with volume scale. Exact solution to the corresponding equations are obtained. The EoS parameter for dark energy as well as deceleration parameter is found to be the time varying functions. A qualitative picture of the evolution of the universe corresponding to different of its stages is given using the latest observational data.

  20. Time-dependent toroidal compactification proposals and the Bianchi type II model: Classical and quantum solutions

    Science.gov (United States)

    Socorro, J.; Toledo Sesma, L.

    2016-03-01

    In this work we construct an effective four-dimensional model by compactifying a ten-dimensional theory of gravity coupled with a real scalar dilaton field on a time-dependent torus without the contributions of fluxes as first approximation. This approach is applied to anisotropic cosmological Bianchi type II model for which we study the classical coupling of the anisotropic scale factors with the two real scalar moduli produced by the compactification process. Also, we present some solutions to the corresponding Wheeler-DeWitt (WDW) equation in the context of Standard Quantum Cosmology and we claim that these quantum solution are generic in the moduli scalar field for all Bianchi Class A models. Also we give the relation to these solutions for asymptotic behavior to large argument in the corresponding quantum solution in the gravitational variables and compare with Bohm's solutions, finding that this corresponds to the lowest-order WKB approximation.