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Sample records for model story focused

  1. Regulatory focus in the life story: prevention and promotion as expressed in three layers of personality.

    Science.gov (United States)

    Manczak, Erika M; Zapata-Gietl, Claudia; McAdams, Dan P

    2014-01-01

    Regulatory Focus Theory (Higgins, 1997) outlines the ways in which people attempt to achieve the presence of positive outcomes (promotion) or preserve the absence of negative outcomes (prevention), suggesting that individuals may differ in chronic orientations. The present work examines regulatory outlooks within a multilayered model of personality composed of dispositional traits, characteristic goals, and life stories (narrative identity). Foregrounding the concept of narrative identity, the current study investigates how narrative themes of prevention and promotion relate to regulatory focus as expressed in dispositional traits and characteristic goals and explores the relative contribution of each layer of personality to psychological well-being and physical health. The findings suggest that dispositional traits, personal goals, and life narratives cohere loosely around the central themes of prevention and promotion. Moreover, promotion focus across layers of personality was related to higher levels of self-reported quality of life, compared to prevention focus. Illustrating the incremental validity of different layers of personality, promotion focus in life stories independently predicted psychological health above and beyond promotion focus in dispositional traits.

  2. English Idioms and Iranian Beginner Learners: A Focus on Short Stories and Pictures

    Science.gov (United States)

    Mehrpour, Saeed; Mansourzadeh, Nurullah

    2017-01-01

    Idiomatic expressions are among the most difficult and challenging aspects in the realm of lexicon. The focus of the present study was on investigating the effect of short stories and pictures on learning idiomatic expressions by beginner EFL learners. For this aim, 52 Iranian EFL learners were chosen and assigned to three groups randomly: two…

  3. When Video Games Tell Stories: A Model of Video Game Narrative Architectures

    OpenAIRE

    Marcello Arnaldo Picucci

    2014-01-01

    In the present study a model is proposed offering a comprehensive categorization of video game narrative structures intended as the methods and techniques used by game designers and allowed by the medium to deliver the story content throughout the gameplay in collaboration with the players. A case is first made for the presence of narrative in video games and its growth of importance as a central component in game design. An in-depth analysis ensues focusing on how games tell stories, guided ...

  4. Dense Plasma Focus Modeling

    Energy Technology Data Exchange (ETDEWEB)

    Li, Hui [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Li, Shengtai [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Jungman, Gerard [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Hayes-Sterbenz, Anna Catherine [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-08-31

    The mechanisms for pinch formation in Dense Plasma Focus (DPF) devices, with the generation of high-energy ions beams and subsequent neutron production over a relatively short distance, are not fully understood. Here we report on high-fidelity 2D and 3D numerical magnetohydrodynamic (MHD) simulations using the LA-COMPASS code to study the pinch formation dynamics and its associated instabilities and neutron production.

  5. When Video Games Tell Stories: A Model of Video Game Narrative Architectures

    Directory of Open Access Journals (Sweden)

    Marcello Arnaldo Picucci

    2014-11-01

    Full Text Available In the present study a model is proposed offering a comprehensive categorization of video game narrative structures intended as the methods and techniques used by game designers and allowed by the medium to deliver the story content throughout the gameplay in collaboration with the players. A case is first made for the presence of narrative in video games and its growth of importance as a central component in game design. An in-depth analysis ensues focusing on how games tell stories, guided by the criteria of linearity/nonlinearity, interactivity and randomness. Light is shed upon the fundamental architectures through which stories are told as well as the essential boundaries posed by the close link between narrative and game AI.

  6. Sensing Story Elements and Structure in Good Literature, the Models for Children's Writing.

    Science.gov (United States)

    Vilscek, Elaine

    1990-01-01

    Discusses how teachers can build upon childrens' natural sense of story, identify good books to serve as models of story elements and structure, and highlight the worth of an author's or illustrator's techniques of story craft as models for improved student writing. (SR)

  7. Niche models tell half the story

    DEFF Research Database (Denmark)

    Swab, Rebecca Marie; Regan, Helen M.; Keith, David A.

    2012-01-01

    Aim  While niche models are typically used to assess the vulnerability of species to climate change, they have been criticized for their limited assessment of threats other than climate change. We attempt to evaluate this limitation by combining niche models with life-history models to investigate...... providing a greater understanding of the impacts of global change than would be gained by niche models alone. Further investigations of this type could elucidate how particular bioecological factors can affect certain types of species under global change....... the relative influence of climate change and a range of fire regimes on the viability of a long-lived plant population. Specifically, we investigate whether range shift due to climate change is a greater threat to an obligate seeding fire-prone shrub than altered fire frequency and how these two threatening...

  8. Life Story of Chinese College Students with Perfectionism Personality: A Qualitative Study Based on a Life Story Model

    Science.gov (United States)

    Ma, Min; Zi, Fei

    2015-01-01

    This manuscript aims to explore and delineate the common characteristics of college students with perfectionism, to promote an in-depth understanding of dynamic personality development of perfectionists from the views of life story model proposed by McAdams (1985). The researchers adopted a narrative qualitative research method. The life stories…

  9. FOCUS: A Model of Sensemaking

    Science.gov (United States)

    2007-05-01

    on this model in Year 2 as theories about sensemaking changed. The following is a description of sensemaking as it was described in Year 1 of this...frames, seeking a frame, and refraining. In relating the current work to earlier concepts by Piaget , we proposed ways in which cycles of assimilation...and accommodation encompass the six activities. " Possibility theory : Klein et al. (2002) referred to quasi-logical reasoning, which we extended into

  10. Earth Expeditions: Telling the stories of eight NASA field campaigns by focusing on the human side of science

    Science.gov (United States)

    Bell, S.

    2016-12-01

    NASA's Earth Right Now communication team kicked off an ambitious multimedia campaign in March 2016 to tell the stories of eight major field campaigns studying regions of critical change from the land, sea and air. Earth Expeditions focused on the human side of science, with live reporting from the field, behind-the-scenes images and videos, and extended storytelling over a six-month period. We reported from Greenland to Namibia, from the eastern United States to the South Pacific. Expedition scientists explored ice sheets, air quality, coral reefs, boreal forests, marine ecosystems and greenhouse gases. All the while the campaign communications team was generating everything from blog posts and social media shareables, to Facebook Live events and a NASA TV series. We also participated in community outreach events and pursued traditional media opportunities. A massive undertaking, we will share lessons learned, best practices for social media and some of our favorite moments when science communication touched our audience's lives.

  11. Task-focused modeling in automated agriculture

    Science.gov (United States)

    Vriesenga, Mark R.; Peleg, K.; Sklansky, Jack

    1993-01-01

    Machine vision systems analyze image data to carry out automation tasks. Our interest is in machine vision systems that rely on models to achieve their designed task. When the model is interrogated from an a priori menu of questions, the model need not be complete. Instead, the machine vision system can use a partial model that contains a large amount of information in regions of interest and less information elsewhere. We propose an adaptive modeling scheme for machine vision, called task-focused modeling, which constructs a model having just sufficient detail to carry out the specified task. The model is detailed in regions of interest to the task and is less detailed elsewhere. This focusing effect saves time and reduces the computational effort expended by the machine vision system. We illustrate task-focused modeling by an example involving real-time micropropagation of plants in automated agriculture.

  12. Comparing and Using Occupation-Focused Models.

    Science.gov (United States)

    Wong, Su Ren; Fisher, Gail

    2015-01-01

    As health care moves toward understanding the importance of function, participation and occupation, occupational therapists would be well served to use occupation-focused theories to guide intervention. Most therapists understand that applying occupation-focused models supports best practice, but many do not routinely use these models. Barriers to application of theory include lack of understanding of the models and limited strategies to select and apply them for maximum client benefit. The aim of this article is to compare occupation-focused models and provide recommendations on how to choose and combine these models in practice; and to provide a systematic approach for integrating occupation-focused models with frames of reference to guide assessment and intervention.

  13. The Straits Chinese Contribution to Malaysian Literary Heritage: Focus on Chinese Stories Translated into Baba Malay

    Directory of Open Access Journals (Sweden)

    S.K. Yoong

    2004-12-01

    Full Text Available The Chinese born in the Straits Settlements of Peninsula Malaya (Penang, Singapore, Malacca are called Babas to distinguish them from those born in China. The Babas are rooted from three different races, Chinese, Malay and English and as such their lifestyles show a mixed blend of the Chinese, Malay and European cultures. Because of this cultural background, the Babas exhibited a unique cultural mix in the clothes they wear, their culinary skills, architectural styles, language and literature. The paper describes the characteristics of 68 Baba translated works published between 1889 and 1950; focusing on the publication trends between the period under study, the persons involved in the creative output, the publishers and printers involved, the contents of the translated works, the physical make-up of the works and the libraries where these works are held.

  14. Enhancing the conversation skills of a boy with Asperger's Disorder through Social Stories and video modeling.

    Science.gov (United States)

    Scattone, Dorothy

    2008-02-01

    This study combined Social Stories with video modeling in an effort to enhance the conversation skills of a boy with Asperger's Disorder. Treatment consisted of two components: (a) observation of video taped Social Stories that included two adults modeling targeted conversational skills and (b) 5-min social interactions. A multiple baseline design across behaviors was used to evaluate the intervention and an increase in 2 out of 3 targeted conversation skills occurred. In addition, generalized behavior changes were observed. These findings provide support for including Social Stories as part of a video treatment package in teaching complex social interaction behaviors to young children with Asperger's Disorder.

  15. Communicative Daily Life Stories and Focus Groups: Proposals for Overcoming Gender Violence among Teenagers

    Science.gov (United States)

    Aubert, Adriana; Melgar, Patricia; Valls, Rosa

    2011-01-01

    The scientific literature has identified an attraction toward models of masculinity marked by abuse and domination in teenagers' sexual and affective relationships. Given this reality, greater insight is needed on the mechanisms that lead young people to choose this type of relationship. In theory, different authors argue that as a result of the…

  16. Life Stories in Context: Using the Three-Sphere Context Model To Analyze Amos's Narrative

    Directory of Open Access Journals (Sweden)

    Rivka Tuval-Mashiach

    2014-07-01

    Full Text Available Despite a wide theoretical consensus among narrative researchers about the importance of referring to context in analyzing narratives, it seems that the various contexts at work in individual life stories and the specific methodological implications of the importance of context are not that clear. In this paper, I will describe a model for context analysis, which refers to three distinct spheres of contexts in which narrators situate their life stories (Zilber, Tuval-Mashiach, & Lieblich, 2008. The first context involves the immediate inter-subjective relationships within and involving which a narrative is produced; the second comprises the collective social field in which a life and story have evolved; and the third surrounds the systems of broad cultural meaning or meta-narratives that underlie and give sense to any particular life story. In the second part of the paper, I will illustrate the three contexts in Amos's story, and claim that viewing his story as it is embedded through these three contexts not only situates it within a more general social framework, but also enables a deeper understanding of his identity and the core themes of his life-story.

  17. Life Stories in Context: Using the Three-Sphere Context Model To Analyze Amos's Narrative

    OpenAIRE

    Rivka Tuval-Mashiach

    2014-01-01

    Despite a wide theoretical consensus among narrative researchers about the importance of referring to context in analyzing narratives, it seems that the various contexts at work in individual life stories and the specific methodological implications of the importance of context are not that clear. In this paper, I will describe a model for context analysis, which refers to three distinct spheres of contexts in which narrators situate their life stories (Zilber, Tuval-Mashiach, & Lieblich, 200...

  18. A focused information criterion for graphical models

    NARCIS (Netherlands)

    Pircalabelu, E.; Claeskens, G.; Waldorp, L.

    2015-01-01

    A new method for model selection for Gaussian Bayesian networks and Markov networks, with extensions towards ancestral graphs, is constructed to have good mean squared error properties. The method is based on the focused information criterion, and offers the possibility of fitting individual-tailore

  19. Designing a story database for use in automatic story generation

    NARCIS (Netherlands)

    Oinonen, K.M.; Theune, M.; Nijholt, A.; Uijlings, J.R.R.; Harper, R.; Rauterberg, M.; Combetto, M.

    2006-01-01

    In this paper we propose a model for the representation of stories in a story database. The use of such a database will enable computational story generation systems to learn from previous stories and associated user feedback, in order to create believable stories with dramatic plots that invoke an

  20. Enhancing the Conversation Skills of a Boy with Asperger's Disorder through Social Stories[TM] and Video Modeling

    Science.gov (United States)

    Scattone, Dorothy

    2008-01-01

    This study combined Social Stories with video modeling in an effort to enhance the conversation skills of a boy with Asperger's Disorder. Treatment consisted of two components: (a) observation of video taped Social Stories that included two adults modeling targeted conversational skills and (b) 5-min social interactions. A multiple baseline design…

  1. Effects of Modeling, Story Templates, and Self-Graphing in the Use of Story Elements by Students with Moderate Intellectual Disability

    Science.gov (United States)

    Pennington, Robert; Koehler, Mallory

    2017-01-01

    There is limited research on teaching narrative writing skills to students with moderate to severe intellectual disability. In the current study, we used a multiple probe across participants single case design to evaluate the effects of an intervention package comprised of modeling, story templates, and self-graphing, on the inclusion of story…

  2. Analysis and modeling of "focus" in context

    DEFF Research Database (Denmark)

    Hovy, Dirk; Anumanchipalli, Gopala; Parlikar, Alok

    2013-01-01

    This paper uses a crowd-sourced definition of a speech phenomenon we have called focus. Given sentences, text and speech, in isolation and in context, we asked annotators to identify what we term the focus word. We present their consistency in identifying the focused word, when presented with text...

  3. DEVELOPMENT OF MATHEMATICAL MODEL OF THE HEATING SYSTEM OF THE MULTI-STORIED HOUSE

    Directory of Open Access Journals (Sweden)

    Postolatii V.M.

    2009-08-01

    Full Text Available The mathematical model of a heating system of the multi-storied house is developed, allowing solving a problem of distribution between apartments of heat of the centralized heat supply. It is taken into account own independently developed heat, which is determinate by means of individual counters of gas and the electric power. Basic feature of model is the opportunity of the account of mutual heat exchange between apartments.

  4. Modelling clinical systemic lupus erythematosus: similarities, differences and success stories.

    Science.gov (United States)

    Celhar, Teja; Fairhurst, Anna-Marie

    2016-12-24

    Mouse models of SLE have been indispensable tools to study disease pathogenesis, to identify genetic susceptibility loci and targets for drug development, and for preclinical testing of novel therapeutics. Recent insights into immunological mechanisms of disease progression have boosted a revival in SLE drug development. Despite promising results in mouse studies, many novel drugs have failed to meet clinical end points. This is probably because of the complexity of the disease, which is driven by polygenic predisposition and diverse environmental factors, resulting in a heterogeneous clinical presentation. Each mouse model recapitulates limited aspects of lupus, especially in terms of the mechanism underlying disease progression. The main mouse models have been fairly successful for the evaluation of broad-acting immunosuppressants. However, the advent of targeted therapeutics calls for a selection of the most appropriate model(s) for testing and, ultimately, identification of patients who will be most likely to respond.

  5. Modelling clinical systemic lupus erythematosus: similarities, differences and success stories

    Science.gov (United States)

    Celhar, Teja

    2017-01-01

    Abstract Mouse models of SLE have been indispensable tools to study disease pathogenesis, to identify genetic susceptibility loci and targets for drug development, and for preclinical testing of novel therapeutics. Recent insights into immunological mechanisms of disease progression have boosted a revival in SLE drug development. Despite promising results in mouse studies, many novel drugs have failed to meet clinical end points. This is probably because of the complexity of the disease, which is driven by polygenic predisposition and diverse environmental factors, resulting in a heterogeneous clinical presentation. Each mouse model recapitulates limited aspects of lupus, especially in terms of the mechanism underlying disease progression. The main mouse models have been fairly successful for the evaluation of broad-acting immunosuppressants. However, the advent of targeted therapeutics calls for a selection of the most appropriate model(s) for testing and, ultimately, identification of patients who will be most likely to respond. PMID:28013204

  6. Shaping a Stories of Resilience Model from urban American Indian elders' narratives of historical trauma and resilience.

    Science.gov (United States)

    Reinschmidt, Kerstin M; Attakai, Agnes; Kahn, Carmella B; Whitewater, Shannon; Teufel-Shone, Nicolette

    2016-01-01

    American Indians (AIs) have experienced traumatizing events but practice remarkable resilience to large-scale and long-term adversities. Qualitative, community-based participatory research served to collect urban AI elders' life narratives on historical trauma and resilience strategies. A consensus group of 15 elders helped finalize open-ended questions that guided 13 elders in telling their stories. Elders shared multifaceted personal stories that revealed the interconnectedness between historical trauma and resilience, and between traditional perceptions connecting past and present, and individuals, families, and communities. Based on the elders' narratives, and supported by the literature, an explanatory Stories of Resilience Model was developed.

  7. Stories on the go

    DEFF Research Database (Denmark)

    Madsen, Karen Hvidtfeldt

    2014-01-01

    The article focuses on 1001 Stories of Denmark: an internet site and a mobile app that collects and displays stories and visual material connected to places all over Denmark. This site offers a “social media-like” communication frame with various levels of participation. But in reality, 1001 stor...

  8. Stories on the go

    DEFF Research Database (Denmark)

    Madsen, Karen Hvidtfeldt

    2014-01-01

    The article focuses on 1001 Stories of Denmark: an internet site and a mobile app that collects and displays stories and visual material connected to places all over Denmark. This site offers a “social media-like” communication frame with various levels of participation. But in reality, 1001 stor...

  9. A focus on building information modelling.

    Science.gov (United States)

    Ryan, Alison

    2014-03-01

    With the Government Construction Strategy requiring a strengthening of the public sector's capability to implement Building Information Modelling (BIM) protocols, the goal being that all central government departments will be adopting, as a minimum, collaborative Level 2 BIM by 2016, Alison Ryan, of consulting engineers, DSSR, explains the principles behind BIM, its history and evolution, and some of the considerable benefits it can offer. These include lowering capital project costs through enhanced co-ordination, cutting carbon emissions, and the ability to manage facilities more efficiently.

  10. "Like throwing a bowling ball at a battle ship" audience responses to Australian news stories about alcohol pricing and promotion policies: a qualitative focus group study.

    Directory of Open Access Journals (Sweden)

    Andrea S Fogarty

    Full Text Available INTRODUCTION: Policies affecting alcohol's price and promotion are effective measures to reduce harms. Yet policies targeting populations are unpopular with the public, whose views can be influenced by news framings of policy narratives. In Australia, alcohol taxation receives high news coverage, while advertising restrictions have not until recently, and narratives are highly contested for each. However, research specifically examining how audiences respond to such news stories is scant. We sought to explore audience understanding of news reports about two alcohol policy proposals. METHOD: From June to August 2012, 46 participants were recruited for 8 focus groups in age-brackets of young people aged 18-25 years, parents of young people, and adults aged 25 or older. Groups were split by education. Participants were asked their prior knowledge of alcohol policies, before watching and discussing four news stories about alcohol taxation and advertising. RESULTS: Participants were clear that alcohol poses problems, yet thought policy solutions were ineffective in a drinking culture they viewed as unamenable to change and unaffected by alcohol's price or promotion. Without knowledge of its actual effect on consumption, they cited the 2008 alcopops tax as a policy failure, blaming cheaper substitution. Participants had low knowledge of advertising restrictions, yet were concerned about underage exposure. They offered conditional support for restrictions, while doubting its effectiveness. There was marked distrust of statistics and news actors in broadcasts, yet discussions matched previous research findings. CONCLUSIONS: News coverage has resulted in strong audience understanding of alcohol related problems but framed solutions have not always provided clear messages, despite audience support for policies. Future advocacy will need to continue recent moves to address the links between alcohol's price and promotion with the drinking culture, as well

  11. Efficient Focusing Models for Generation of Freak Waves

    Institute of Scientific and Technical Information of China (English)

    ZHAO Xi-zeng; SUN Zhao-chen; LIANG Shu-xiu

    2009-01-01

    Four focusing models for generation of freak waves are presented. An extreme wave focusing model is presented on the basis of the enhanced High-Order Spectral (HOS) method and the importance of the nonlinear wave-wave interaction is evaluated by comparison of the calculated results with experimental and theoretical data. Based on the modification of the Longuet-Higgins model, four wave models for generation of freak waves (a. Extreme wave model + random wave model; b. Extreme wave model + regular wave model; c. Phase interval modulation wave focusing model; d. Number modulation wave focusing model with the same phase) are proposed. By use of different energy distribution techniques in the four models, freak wave events are obtained with different H_(max)/H_s in finite space and time.

  12. Analyzing Teachers' Stories

    Directory of Open Access Journals (Sweden)

    Anat Kainan

    2002-09-01

    Full Text Available This article presents an integrated socio-literal approach as a way to analyze work stories. It uses a case of teachers' stories about the administration as an example. The stories focus on grumbles about various activities of members of the management of a school in a small town. The complaints appear in descriptions of the action, the characters, and, in particular, in the way the story is presented to the audience. The stories present a situation of two opposing groups-the administration and the teachers. The presentation of the stories creates a sense of togetherness among the veterans and new teachers in the staff room, and helps the integration of the new teachers into the staff. The veterans use the stories as an opportunity to express their anger at not having been assigned responsibilities on the one hand and their hopes of such promotion on the other. The stories act as a convenient medium to express criticism without entering into open hostilities. Behind them, a common principle can be discerned- the good of the school. The stories describe the infringement of various aspects of the school's social order, and it is possible to elicit from them what general pattern the teachers want to preserve in the school.

  13. Short Cuts: A Model of Using the Shortest Stories To Teach Second Language Reading Skill.

    Science.gov (United States)

    Goetz, Lily Anne

    2003-01-01

    Discuses the use of micro stories--shorter short stories--in the Spanish language classroom. Highlights the use of one micro story--Monterrosos'"El dinasauro"--as a point of departure for teaching literary reading skill to intermediate college and secondary level students. (Author/VWL)

  14. The Dialectic between Ideal and Real Forms of "Sharing": A Cultural-Historical Study of Story Acting through Imaginary Play at Home

    Science.gov (United States)

    Hao, Yijun

    2017-01-01

    In a time when story-acting practices have gained increasing focus, little is known about the relations between family story acting and a child's interactions with the ideal models represented in stories. Drawing upon a cultural-historical perspective of play and development, this study is aimed at discovering how a child is able to interact with…

  15. HELIOS modelling of point-focusing solar concentrators

    Science.gov (United States)

    Strachan, J. W.; Mulholland, G. P.

    The modifications to the optical code HELIOS which are required in order to model point-focusing concentrators is presented. HELIOS simulates the optical behavior of reflecting heliostats and was written to model central receiver facilities, specifically that of the Solar Thermal Test Facility at Sandia National Laboratories in Albuquerque, New Mexico. This paper discusses the necessary changes to the HELIOS code and to its input files such that it can successfully model point-focusing concentrators while retaining its computational power. A point-focusing concentrator located at the Solar Thermal Test Facility is presented as a sample case.

  16. From Storyboard to Story: Animation Content Development

    Science.gov (United States)

    Mou, Tsai-Yun; Jeng, Tay-Sheng; Chen, Chien-Hsu

    2013-01-01

    This research focused on a new method in the development of animation story content, which could shorten the creation process and arouse new ideas. Two phases of experiments were conducted to explore this reversed model. The first phase is a pretest of participants' creativity, which was a base for further examination the relationship between…

  17. Stories on the go

    DEFF Research Database (Denmark)

    Madsen, Karen Hvidtfeldt

    2014-01-01

    The article focuses on 1001 Stories of Denmark: an internet site and a mobile app that collects and displays stories and visual material connected to places all over Denmark. This site offers a “social media-like” communication frame with various levels of participation. But in reality, 1001...... and affective narratives. I argue that these videos and stories demonstrate the potential of mobile and digital cultural heritage sites; however, it requires strategic initiatives and long-term engagement from museums and cultural institutions to create and maintain the level of the dialogue and participation....

  18. A Deformable Model for Bringing Particles in Focus

    DEFF Research Database (Denmark)

    Dahl, Anders Lindbjerg; Jørgensen, Thomas Martini; Larsen, Rasmus

    2010-01-01

    We provide a deformable model for particle analysis. We in- vestigate particle images from a backlit microscope system where parti- cles suer from out-of-focus blur. The blur is a result of particles being in front or behind the focus plane, and the out-of-focus gives a bias towards overestimatin...... demonstrate the capa- bilities of our model on both real and simulated data, and our approach shows promising results for a reliable particle analysis. The potential is more process information obtained over shorter sampling time....

  19. The Power of Story

    Science.gov (United States)

    Cohen, Don; Fox, Jessica

    2008-01-01

    A major knowledge-sharing issue that is the source of many project problems: how to communicate our intentions so that the information received is the same as the information given. One answer is conversation-the back-and-forth of statement, question, and response that gradually brings talkers and listeners to a shared understanding. Stories also offer a way to share knowledge effectively. While the story teller's intent and the listener's interpretation will not be identical, a good story reliably communicates essential knowledge so it is not only understood but absorbed and embraced. Narrative is one of the oldest knowledge-transfer systems in the world. Religion knows it. Politicians know it. Fairytales know it. Now, knowledge management practitioners are coming to know it, too. But why are stories such a powerful knowledge-transfer tool? And what kinds of knowledge do they transfer? Joseph Campbell, the mythologist, defined stories as serving four major functions: the mystical, the cosmological, the sociological, and the pedagogical. The mystical function of narrative lies in its ability to open up emotional realization that often connects with a transcendent idea such as love or forgiveness. He calls this realization "mystical" because it connects the self with the universal. What Campbell calls the cosmological function of stories relates the self to the outside world, focusing on action, on understanding cause and effect and our role in it. For the cosmological function of stories "to be up to date and really to work in the minds of people who are living in the modern scientific world," Campbell notes, "it must incorporate the modern scientific world." We must continually tell stories that demonstrate our current vision of the world. The sociological function of stories, Campbell explains, helps maintain and validate the social order of a society. Stories pass on information about power relationships, taboos, laws, and the inner workings of communities

  20. "Robinson Crusoe" and the Story of the Novel.

    Science.gov (United States)

    Kraft, Quentin G.

    1980-01-01

    Discusses stories in general, stories in the novel, and "Robinson Crusoe," focusing on what happens in and to narrative--the transformation in the nature of story--that brings the novel into existence. (DD)

  1. "Robinson Crusoe" and the Story of the Novel.

    Science.gov (United States)

    Kraft, Quentin G.

    1980-01-01

    Discusses stories in general, stories in the novel, and "Robinson Crusoe," focusing on what happens in and to narrative--the transformation in the nature of story--that brings the novel into existence. (DD)

  2. Effects of Mother-Delivered Social Stories and Video Modeling in Teaching Social Skills to Children with Autism Spectrum Disorders

    Science.gov (United States)

    Acar, Cimen; Tekin-Iftar, Elif; Yikmis, Ahmet

    2017-01-01

    An adapted alternating treatments design was used to compare mother-developed and delivered social stories and video modeling in teaching social skills to children with autism spectrum disorder (ASD). Mothers' opinions about the social validity of the study were also examined. Three mother-child dyads participated in the study. Results showed that…

  3. The Combined Use of Video Modeling and Social Stories in Teaching Social Skills for Individuals with Intellectual Disability

    Science.gov (United States)

    Gül, Seray Olçay

    2016-01-01

    There are many studies in the literature in which individuals with intellectual disabilities exhibit social skills deficits and which show the need for teaching these skills systematically. This study aims to investigate the effects of an intervention package of consisting computer-presented video modeling and Social Stories on individuals with…

  4. Effects of Mother-Delivered Social Stories and Video Modeling in Teaching Social Skills to Children with Autism Spectrum Disorders

    Science.gov (United States)

    Acar, Cimen; Tekin-Iftar, Elif; Yikmis, Ahmet

    2017-01-01

    An adapted alternating treatments design was used to compare mother-developed and delivered social stories and video modeling in teaching social skills to children with autism spectrum disorder (ASD). Mothers' opinions about the social validity of the study were also examined. Three mother-child dyads participated in the study. Results showed that…

  5. SHORT STORIES IN THE BALKANS AND CONTEMPORARYSHORT STORIES IN THE WORLD

    Directory of Open Access Journals (Sweden)

    Larisa Softic - Gasal

    2014-01-01

    Full Text Available A comparative analysis of selected short stories in the Balkan countries, as well as contemporary short stories of the world, will show us that the key themes of those stories are very similar to the short stories written during the period of transition in Bosnia and Herzegovina (1995-2010. For example, the story of the Soul Operation by an Iranian writer Mohsen Mahmalbafa, The Falcons by a Dutch writer Kader Abdolaha and On the Kitchen Stairs by a Polish writer Witold Gombrowic zinter connect with short stories by authors from Bosnia and Herzegovina, such as The Secret of Raspberry jam by Karim Zaimović or The Devilish work of Zoran Riđanović. A common thread manifests itself in the aforementioned stories, more specifically, a common theme which focuses on the need for eradication of the seeds of submission and compliance with the political system. Most authors focus on their domestic political systems; however, some portray and analyze systems in other countries as they see it, such as a Dutch narrator who focuses on a potential threat of infringement of human freedom. Moreover, Bellow Hubei by an Argentinian writer Anhelika Gorodis her underlines the importance of humanization within a political order. Faruk Šehić examines the political system in Bosnia and Herzegovina from a slightly different perspective. His collection of stories Under Pressure emphases the issue of pressure in the above war model of short stories in Bosnia and Herzegovina. These stories are the product of pressure and anxiety, with intent to latently promote new ways of spiritual survival, directly relating to the concept and the theme of the story The Past Age Man by Christian Karlson Stead. Further analysis of the alienation theme singled out short stories in Bosnia and Herzegovina, Plants are Something Else by Alma Lazarevska and Dialogues by Lamija Begagić, and pointed out their connection with some recent international short stories such as The Last Defence by

  6. Stories on Research, Research on Stories

    Science.gov (United States)

    Petit, Sandrine; Mougenot, Catherine; Fleury, Philippe

    2011-01-01

    This article deals with a group of researchers involved in Participatory Action Research projects on biodiversity and who volunteered to take part in a "storytelling" experiment. Their "stories" were used to describe this new type of research collective comprising various partners, including researchers and managers, focused on obtaining directly…

  7. Current focusing and steering: modeling, physiology, and psychophysics.

    Science.gov (United States)

    Bonham, Ben H; Litvak, Leonid M

    2008-08-01

    Current steering and current focusing are stimulation techniques designed to increase the number of distinct perceptual channels available to cochlear implant (CI) users by adjusting currents applied simultaneously to multiple CI electrodes. Previous studies exploring current steering and current focusing stimulation strategies are reviewed, including results of research using computational models, animal neurophysiology, and human psychophysics. Preliminary results of additional neurophysiological and human psychophysical studies are presented that demonstrate the success of current steering strategies in stimulating auditory nerve regions lying between physical CI electrodes, as well as current focusing strategies that excite regions narrower than those stimulated using monopolar configurations. These results are interpreted in the context of perception and speech reception by CI users. Disparities between results of physiological and psychophysical studies are discussed. The differences in stimulation used for physiological and psychophysical studies are hypothesized to contribute to these disparities. Finally, application of current steering and focusing strategies to other types of auditory prostheses is also discussed.

  8. Light self-focusing in the atmosphere: thin window model

    Science.gov (United States)

    Vaseva, Irina A.; Fedoruk, Mikhail P.; Rubenchik, Alexander M.; Turitsyn, Sergei K.

    2016-08-01

    Ultra-high power (exceeding the self-focusing threshold by more than three orders of magnitude) light beams from ground-based laser systems may find applications in space-debris cleaning. The propagation of such powerful laser beams through the atmosphere reveals many novel interesting features compared to traditional light self-focusing. It is demonstrated here that for the relevant laser parameters, when the thickness of the atmosphere is much shorter than the focusing length (that is, of the orbit scale), the beam transit through the atmosphere in lowest order produces phase distortion only. This means that by using adaptive optics it may be possible to eliminate the impact of self-focusing in the atmosphere on the laser beam. The area of applicability of the proposed “thin window” model is broader than the specific physical problem considered here. For instance, it might find applications in femtosecond laser material processing.

  9. A model of visual, aesthetic communication focusing on web sites

    DEFF Research Database (Denmark)

    Thorlacius, Lisbeth

    2002-01-01

    Theory books and method books within the field of web design mainly focus on the technical and functional aspects of the construction of web design. There is a lack of a model which weighs the analysis of the visual and aesthetic aspects against the the functional and technical aspects of web des...

  10. Neurokinin B and reproductive functions: "KNDy neuron" model in mammals and the emerging story in fish.

    Science.gov (United States)

    Hu, Guangfu; Lin, Chengyuan; He, Mulan; Wong, Anderson O L

    2014-11-01

    In mammals, neurokinin B (NKB), the gene product of the tachykinin family member TAC3, is known to be a key regulator for episodic release of luteinizing hormone (LH). Its regulatory actions are mediated by a subpopulation of kisspeptin neurons within the arcuate nucleus with co-expression of NKB and dynorphin A (commonly called the "KNDy neurons"). By forming an "autosynaptic feedback loop" within the hypothalamus, the KNDy neurons can modulate gonadotropin-releasing hormone (GnRH) pulsatility and subsequent LH release in the pituitary. NKB regulation of LH secretion has been recently demonstrated in zebrafish, suggesting that the reproductive functions of NKB may be conserved from fish to mammals. Interestingly, the TAC3 genes in fish not only encode the mature peptide of NKB but also a novel tachykinin-like peptide, namely NKB-related peptide (or neurokinin F). Recent studies in zebrafish also reveal that the neuroanatomy of TAC3/kisspeptin system within the fish brain is quite different from that of mammals. In this article, the current ideas of "KNDy neuron" model for GnRH regulation and steroid feedback, other reproductive functions of NKB including its local actions in the gonad and placenta, the revised model of tachykinin evolution from invertebrates to vertebrates, as well as the emerging story of the two TAC3 gene products in fish, NKB and NKB-related peptide, will be reviewed with stress on the areas with interesting questions for future investigations.

  11. Artifacts as Stories: Understanding Families, Digital Literacies, and Storied Lives

    Science.gov (United States)

    Lewis Ellison, Tisha

    2016-01-01

    This column focuses on the interactions during family and group conversation circles that not only helped participants talk about personal, emotional, and social issues in their digital stories but also helped them make sense of artifacts and the meanings that stories carry in shared spaces and practices. This work adds to the bourgeoning…

  12. Artifacts as Stories: Understanding Families, Digital Literacies, and Storied Lives

    Science.gov (United States)

    Lewis Ellison, Tisha

    2016-01-01

    This column focuses on the interactions during family and group conversation circles that not only helped participants talk about personal, emotional, and social issues in their digital stories but also helped them make sense of artifacts and the meanings that stories carry in shared spaces and practices. This work adds to the bourgeoning…

  13. Tarikh-e Beyhaghi based on Greimas' actants model Semiotic-structural analysis of two stories from

    Directory of Open Access Journals (Sweden)

    نرگس خادمی

    2010-12-01

    Full Text Available Greimas and other semioticians of the Paris School believe that reality is always illusive and that the factors affecting the formation of a narrative are always ambiguous. Based on this view, a narrative is always a simulation of reality. Based on Greimas' actants model, this paper presents an analysis of two stories from Tarikh-e Beyhaghi, with the aim of revealing two types of narratives; the first type cannot be analyzed very well using this model because the author Beyhaghi had no access to authentic details about it and thus presented a poor characterization. The second type can be analyzed using this model because of excellent characterization. The stories reflect reality to a great extent, which shows Beyhaghi's mastery of simulating historical facts in the form of narratives. Keywords: Tarikh-e Beyhaghi, Hasanak, Afshin, Greimas, actant

  14. Focus for 3D city models should be on interoperability

    DEFF Research Database (Denmark)

    Bodum, Lars; Kjems, Erik; Jaegly, Marie Michele Helena

    2006-01-01

    3D city models have become a very popular commodity for cities in general. The politicians and/or the administrative management have in the last few years been very active when it comes to investments in dimensionality, and the models come in many different forms and for many specific or non...... of interoperability. Verisimilarity would in this case mean a 3D model with close resemblance to reality and based on modelling principles from CAD and scenes from this, build with focus on photorealism. Interoperability would mean a 3D model that included semantics in form of an object model and an ontology...... that would make it useful for other purposes than visualisation. Time has come to try to change this trend and to convince the municipalities that interoperability and semantics are important issues for the future. It is important for them to see that 3D modelling, mapping and geographic information...

  15. Webcam Stories

    Science.gov (United States)

    Clidas, Jeanne

    2011-01-01

    Stories, steeped in science content and full of specific information, can be brought into schools and homes through the power of live video streaming. Video streaming refers to the process of viewing video over the internet. These videos may be live (webcam feeds) or recorded. These stories are engaging and inspiring. They offer opportunities to…

  16. Hunting Stories.

    Science.gov (United States)

    Johnson, Frank

    Eleven stories describe traditional practices and true adventures of the Tlingit hunters of Southeast Alaska. The stories are accompanied by learning activities and discussion questions for students and are arranged under the headings of bear, mountain goat and deer, and seal and sea lion. Topics include hunting weapons and strategies, bravery,…

  17. Webcam Stories

    Science.gov (United States)

    Clidas, Jeanne

    2011-01-01

    Stories, steeped in science content and full of specific information, can be brought into schools and homes through the power of live video streaming. Video streaming refers to the process of viewing video over the internet. These videos may be live (webcam feeds) or recorded. These stories are engaging and inspiring. They offer opportunities to…

  18. When do Stories Work?

    DEFF Research Database (Denmark)

    Gelman, Andrew; Basbøll, Thomas

    2014-01-01

    -enough established that they have the potential to indicate problems with a new model). We develop these ideas through considering two well-known examples from the work of Karl Weick and Robert Axelrod, and we discuss why transparent sourcing (in the case of Axelrod) makes a story a more effective research tool......Storytelling has long been recognized as central to human cognition and communication. Here we explore a more active role of stories in social science research, not merely to illustrate concepts but also to develop new ideas and evaluate hypotheses, for example, in deciding that a research method...... is effective. We see stories as central to engagement with the development and evaluation of theories, and we argue that for a story to be useful in this way, it should be anomalous (representing aspects of life that are not well explained by existing models) and immutable (with details that are well...

  19. The Time Is Right to Focus on Model Organism Metabolomes

    Directory of Open Access Journals (Sweden)

    Arthur S. Edison

    2016-02-01

    Full Text Available Model organisms are an essential component of biological and biomedical research that can be used to study specific biological processes. These organisms are in part selected for facile experimental study. However, just as importantly, intensive study of a small number of model organisms yields important synergies as discoveries in one area of science for a given organism shed light on biological processes in other areas, even for other organisms. Furthermore, the extensive knowledge bases compiled for each model organism enable systems-level understandings of these species, which enhance the overall biological and biomedical knowledge for all organisms, including humans. Building upon extensive genomics research, we argue that the time is now right to focus intensively on model organism metabolomes. We propose a grand challenge for metabolomics studies of model organisms: to identify and map all metabolites onto metabolic pathways, to develop quantitative metabolic models for model organisms, and to relate organism metabolic pathways within the context of evolutionary metabolomics, i.e., phylometabolomics. These efforts should focus on a series of established model organisms in microbial, animal and plant research.

  20. The Time Is Right to Focus on Model Organism Metabolomes

    Science.gov (United States)

    Edison, Arthur S.; Hall, Robert D.; Junot, Christophe; Karp, Peter D.; Kurland, Irwin J.; Mistrik, Robert; Reed, Laura K.; Saito, Kazuki; Salek, Reza M.; Steinbeck, Christoph; Sumner, Lloyd W.; Viant, Mark R.

    2016-01-01

    Model organisms are an essential component of biological and biomedical research that can be used to study specific biological processes. These organisms are in part selected for facile experimental study. However, just as importantly, intensive study of a small number of model organisms yields important synergies as discoveries in one area of science for a given organism shed light on biological processes in other areas, even for other organisms. Furthermore, the extensive knowledge bases compiled for each model organism enable systems-level understandings of these species, which enhance the overall biological and biomedical knowledge for all organisms, including humans. Building upon extensive genomics research, we argue that the time is now right to focus intensively on model organism metabolomes. We propose a grand challenge for metabolomics studies of model organisms: to identify and map all metabolites onto metabolic pathways, to develop quantitative metabolic models for model organisms, and to relate organism metabolic pathways within the context of evolutionary metabolomics, i.e., phylometabolomics. These efforts should focus on a series of established model organisms in microbial, animal and plant research. PMID:26891337

  1. The Time Is Right to Focus on Model Organism Metabolomes.

    Science.gov (United States)

    Edison, Arthur S; Hall, Robert D; Junot, Christophe; Karp, Peter D; Kurland, Irwin J; Mistrik, Robert; Reed, Laura K; Saito, Kazuki; Salek, Reza M; Steinbeck, Christoph; Sumner, Lloyd W; Viant, Mark R

    2016-02-15

    Model organisms are an essential component of biological and biomedical research that can be used to study specific biological processes. These organisms are in part selected for facile experimental study. However, just as importantly, intensive study of a small number of model organisms yields important synergies as discoveries in one area of science for a given organism shed light on biological processes in other areas, even for other organisms. Furthermore, the extensive knowledge bases compiled for each model organism enable systems-level understandings of these species, which enhance the overall biological and biomedical knowledge for all organisms, including humans. Building upon extensive genomics research, we argue that the time is now right to focus intensively on model organism metabolomes. We propose a grand challenge for metabolomics studies of model organisms: to identify and map all metabolites onto metabolic pathways, to develop quantitative metabolic models for model organisms, and to relate organism metabolic pathways within the context of evolutionary metabolomics, i.e., phylometabolomics. These efforts should focus on a series of established model organisms in microbial, animal and plant research.

  2. Modeling of space-time focusing of localized nondiffracting pulses

    Science.gov (United States)

    Zamboni-Rached, Michel; Besieris, Ioannis M.

    2016-10-01

    In this paper we develop a method capable of modeling the space-time focusing of nondiffracting pulses. These pulses can possess arbitrary peak velocities and, in addition to being resistant to diffraction, can have their peak intensities and focusing positions chosen a priori. More specifically, we can choose multiple locations (spatial ranges) of space and time focalization; also, the pulse intensities can be chosen in advance. The pulsed wave solutions presented here can have very interesting applications in many different fields, such as free-space optical communications, remote sensing, medical apparatus, etc.

  3. Modeling of Space-Time Focusing of Localized Nondiffracting Pulses

    CERN Document Server

    Zamboni-Rached, Michel

    2015-01-01

    In this paper we develop a method capable of modeling the space-time focusing of nondiffracting pulses. The new pulses can possess arbitrary peak velocities and, in addition to being resistant to diffraction, can have their peak intensities and focusing positions chosen a priori. More specifically, we can choose multiple locations (spatial ranges) of space/time focalization; also, the pulse intensities can be chosen in advance. The pulsed wave solutions presented here can have very interesting applications in many different fields, such as free-space optical communications, remote sensing, medical apparatus, etc.

  4. Digital Media Stories for Persuasion

    Science.gov (United States)

    Leopold, Lisa

    2010-01-01

    Digital media story-telling (which enhances traditional oral story-telling with images, music, and text) has been a focus of recent scholarship for its potential to produce numerous educational benefits. Through digital media storytelling, students' imagination, creativity, critical thinking, writing, public speaking, and organizational or…

  5. Digital Media Stories for Persuasion

    Science.gov (United States)

    Leopold, Lisa

    2010-01-01

    Digital media story-telling (which enhances traditional oral story-telling with images, music, and text) has been a focus of recent scholarship for its potential to produce numerous educational benefits. Through digital media storytelling, students' imagination, creativity, critical thinking, writing, public speaking, and organizational or…

  6. Earthquake simulator tests and associated study of an 1/6-scale nine-story RC model

    Institute of Scientific and Technical Information of China (English)

    Sun Jingjiang; Wang Tao; Qi Hu

    2007-01-01

    Earthquake simulator tests of a 1/6-scale nine-story reinforced concrete frame-wall model are described in the paper. The test results and associated numerical simulation are summarized and discussed. Based on the test data,a relationship between maximum inter-story drift and damage state is established. Equations of variation of structural characteristics (natural frequency and equivalent stiffness) with overall drifts are derived by data fitting, which can be used to estimate structural damage state if structural characteristics can be measured. A comparison of the analytical and experimental results show that both the commonly used equivalent beam and fiber element models can simulate the nonlinear seismic response of structures very well. Finally, conclusions associated with seismic design and damage evaluation of RC structures are presented.

  7. Modelling the interplay of multiple cues in prosodic focus marking

    Directory of Open Access Journals (Sweden)

    Anja Arnhold

    2017-03-01

    Full Text Available Focus marking is an important function of prosody in many languages. While many phonological accounts concentrate on fundamental frequency (F0, studies have established several additional cues to information structure. However, the relationship between these cues is rarely investigated. We simultaneously analyzed five prosodic cues to focus—F0 range, word duration, intensity, voice quality, the location of the F0 maximum, and the occurrence of pauses—in a set of 947 simple Subject Verb Object (SVO sentences uttered by 17 native speakers of Finnish. Using random forest and generalized additive mixed modelling, we investigated the systematicity of prosodic focus marking, the importance of each cue as a predictor, and their functional shape. Results indicated a highly consistent differentiation between narrow focus and givenness, marked by at least F0 range, word duration, intensity, and the location of the F0 maximum, with F0 range being the most important predictor. No cue had a linear relationship with focus condition. To account for the simultaneous significance of several predictors, we argue that these findings support treating multiple prosodic cues to focus in Finnish as correlates of prosodic phrasing. Thus, we suggest that prosodic phrasing, having multiple functions, is also marked with multiple cues to enhance communicative efficiency.

  8. I know my story and I know your story

    DEFF Research Database (Denmark)

    Thomsen, Dorthe Kirkegaard; Pillemer, David B

    2016-01-01

    . Emotion ratings of both personal and vicarious life story chapters were related to personality traits and self-esteem, although relations were more consistent for personal chapters. CONCLUSION: Personal and vicarious life stories share important similarities. Mental models of other people include...... vicarious life stories that serve to expand the self as well as facilitate understanding of others. This article is protected by copyright. All rights reserved....

  9. Personal Digital Video Stories

    DEFF Research Database (Denmark)

    Ørngreen, Rikke; Henningsen, Birgitte Sølbeck; Louw, Arnt Vestergaard

    2016-01-01

    agenda focusing on video productions in combination with digital storytelling, followed by a presentation of the digital storytelling features. The paper concludes with a suggestion to initiate research in what is identified as Personal Digital Video (PDV) Stories within longitudinal settings, while...

  10. Theoretical Stories

    Directory of Open Access Journals (Sweden)

    Tanya Serisier

    2012-03-01

    Full Text Available A review of Clare Hemmings, Why Stories Matter: The Political Grammar of Feminist Theory (Duke 2011 and Janet Halley & Andrew Parker (eds. After Sex? On Writing Since Queer Theory (Duke 2011.

  11. Data Stories

    DEFF Research Database (Denmark)

    Watts, Laura; Nafus, Dawn

    2013-01-01

    ‘Big Data’ rises and accumulates today from so much of our activity, off and online, that our lives seem almost suffused by ‘The Cloud’. But perhaps data might be otherwise? In this collection, Laura Watts and Dawn Nafus, two ethnographers, bring together stories from different data sites: from...... the marine energy industry, and from the Quantified Self movement. These Data Stories speak, not of clouds, but of transformations: in things, in energy, and in experience....

  12. Data Stories

    DEFF Research Database (Denmark)

    Watts, Laura; Nafus, Dawn

    2013-01-01

    ‘Big Data’ rises and accumulates today from so much of our activity, off and online, that our lives seem almost suffused by ‘The Cloud’. But perhaps data might be otherwise? In this collection, Laura Watts and Dawn Nafus, two ethnographers, bring together stories from different data sites: from...... the marine energy industry, and from the Quantified Self movement. These Data Stories speak, not of clouds, but of transformations: in things, in energy, and in experience....

  13. Regaining our humanity through story.

    Science.gov (United States)

    Sierpina, Victor S; Kreitzer, Mary Jo; Mackenzie, Elizabeth; Sierpina, Michelle

    2007-01-01

    In this issue of Innovations in Integrative Healthcare Education, we are departing from our usual format of spotlighting specific projects or programs in lieu of presenting a more extended piece by MacKenzie on relationship-centered care and narrative medicine. The importance of these topics cannot be overestimated in their role of humanizing the healthcare encounter, improving self-awareness of the practitioner, and creating a space in which the patient feels deeply listened to. A commentary by Dr Michelle Sierpina is also included in this special section to put into context the power of narrative in medicine and in patients' lives. Her recent PhD focused on the power of life stories told by seniors; that research and training enables her to provide a broad and scholarly review of the power of story in relation to MacKenzie's article. In the medical school at University of Texas Medical Branch, we send out first-year medical students in the first couple of months of the first semester to patients' homes to just get their story, not a medical history, as part of a required course on the practice of medicine. Many students find this immensely anxiety provoking, due to the lack of structure and familiar context. However, ultimately they find an opportunity to encounter a real person in a nonclinical setting. A scoring rubric based on the construction and quality of a short story allows us to grade the students objectively. However, a most interesting finding, which we expect to present at the Ottawa Conference in Australia next spring, is the process of personal transformation that such story writing has for students. This is also reported by MacKenzie in her article and in Sierpina's accompanying commentary. The importance of capturing and understanding the patient's story is also a major focus in nurse practitioner programs across the United States, where the art of listening and the importance of patient narratives have long been emphasized. In an integrative

  14. Genetic Mouse Models of Huntington's Disease: Focus on Electrophysiological Mechanisms

    Directory of Open Access Journals (Sweden)

    Carlos Cepeda

    2010-03-01

    Full Text Available The discovery of the HD (Huntington's disease gene in 1993 led to the creation of genetic mouse models of the disease and opened the doors for mechanistic studies. In particular, the early changes and progression of the disease could be followed and examined systematically. The present review focuses on the contribution of these genetic mouse models to the understanding of functional changes in neurons as the HD phenotype progresses, and concentrates on two brain areas: the striatum, the site of most conspicuous pathology in HD, and the cortex, a site that is becoming increasingly important in understanding the widespread behavioural abnormalities. Mounting evidence points to synaptic abnormalities in communication between the cortex and striatum and cell-cell interactions as major determinants of HD symptoms, even in the absence of severe neuronal degeneration and death.

  15. Policy stories

    DEFF Research Database (Denmark)

    Ren, Carina Bregnholm; Rasmussen, Rasmus Kjærgaard

    planning and execution and of event outcomes beyond the narrow confines of bed nights and legacies. Second, we introduce policies as an entry point to unlock discussions and manifestations of value and futures which connect to AWG. In order to exemplify the workings of the AWG event in these domains, we...... present three central policy stories from the field. The stories tell of how the event was first interested, then activated and finally evaluated. Besides adding a new understanding to policy-driven events as a locus of value creation, we also argue that the AWG 2016 offer speculative bets for new...

  16. Creative stories: Modelling the principal components of human creativity over texts in a storytelling game

    Directory of Open Access Journals (Sweden)

    Antonis Koukourikos

    2016-07-01

    Full Text Available The process of effectively applying techniques for fostering creativity in educational settings is – by nature – multifaceted and not straightforward, as it pertains to several fields such as cognitive theory and psychology. Furthermore, the quantification of the impact of different activities on creativity is a challenging and not yet thoroughly investigated task. In this paper, we present the process of applying the Semantic Lateral Thinking technique for fostering creativity in Creative Stories, a digital storytelling game, via the introduction of the appropriate stimuli in the game’s flow. Furthermore, we present a formalization for a person’s creativity as a derivative of his/her creations within the game, by transitioning from traditional computational creativity metrics over the produced stories to a space that adheres to the core principles of creativity as perceived by humans.

  17. A mathematical model for storied buildings subjected to automatic loom stresses. [vibration of weaving mill

    Science.gov (United States)

    Stan, A.; Munteanu, M.

    1974-01-01

    Expressions are derived for the displacements of a many storied building subjected to the action of classical weaving looms located at different levels of the building. The building is regarded as a vertical fixed beam with a uniformly distributed mass as well as concentrated masses at each level. The calculation relations are obtained on the assumption of harmonic variation of the forces acting at each level as well as the assumption of narrow band stationary random excitatory forces.

  18. MHD modeling of dense plasma focus electrode shape variation

    Science.gov (United States)

    McLean, Harry; Hartman, Charles; Schmidt, Andrea; Tang, Vincent; Link, Anthony; Ellsworth, Jen; Reisman, David

    2013-10-01

    The dense plasma focus (DPF) is a very simple device physically, but results to date indicate that very extensive physics is needed to understand the details of operation, especially during the final pinch where kinetic effects become very important. Nevertheless, the overall effects of electrode geometry, electrode size, and drive circuit parameters can be informed efficiently using MHD fluid codes, especially in the run-down phase before the final pinch. These kinds of results can then guide subsequent, more detailed fully kinetic modeling efforts. We report on resistive 2-d MHD modeling results applying the TRAC-II code to the DPF with an emphasis on varying anode and cathode shape. Drive circuit variations are handled in the code using a self-consistent circuit model for the external capacitor bank since the device impedance is strongly coupled to the internal plasma physics. Electrode shape is characterized by the ratio of inner diameter to outer diameter, length to diameter, and various parameterizations for tapering. This work performed under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory under Contract DE-AC52-07NA27344.

  19. Two Stories.

    Science.gov (United States)

    Lieberman, Lisa

    2000-01-01

    In this article, the mother of 12-year-old son with autism shares two stories that highlight how her son keeps her humble and how asking for help mutually benefits the giver and receiver. It discusses the need to tell people your needs and to invite them to participate in your life. (CR)

  20. The Analysis of the Story of

    Directory of Open Access Journals (Sweden)

    m Rouhani

    2012-09-01

    The story of Sheikhe Sanan is the longest and most famous story in Manteghol Tayr and it is always considered by researchers of Manteghol Tayr. This story has ups and downs which make possible a Greimasian analysis. Such analysis not only shows the integrity and coherence of the story but also shows the capacities of this model for analyzing the structure of Persian old tales.

  1. The framework of studying personal and family stories

    Directory of Open Access Journals (Sweden)

    Dragana Antonijević

    2016-02-01

    Full Text Available In this paper I suggest the analytical framework for interpreting personal and family stories about the loss of possessions, riches, job, reputation and status. I find the theoretic foothold in the decades long folkloristic and anthropological studies of personal stories and life histories, then in the concept by Gary Alan Fine, a sociologist and folklorist, about the idioculture of small groups through the discussion of the family folklore, and last in the discussion of the historic, social-economic and ideological context where personal and family losses occur. The incentive for me to deal with this type of stories resides in the fact that they have not been the subject of scientific analysis, neither in the world, nor in our country, except one work by an American folklorist Stanley Brandes from 1975, which served as my inspiration and model. The material for the analysis was collected in the form of term papers written by four generations of ethnology and anthropology third year students, attending the course in Folklore anthropology at the Ethnology and Anthropology Department of the Faculty of Philosophy of Belgrade University. A typology of these stories has been done, and they are divided into two groups with subtypes: stories about personal causes to material ruin, and about faith (destiny causing the ruin. Further on in the analysis I focused only on the context of the stories with the so-called "pre-destined (faith" causes of ruin, i.e., on the historic, social-economic and ideological changes in Serbia, which happened during the 20th and at the beginning of the 21st century. The context of the revolutionary takeover of power by the Communists after the World War Two is discussed, as well as the violent dispossession of what was until then private property of many families in Serbia, and transferring that property into state and social possession (the so-called stories about nationalization, and also the specific context of post

  2. Model equation for strongly focused finite-amplitude sound beams

    Science.gov (United States)

    Kamakura; Ishiwata; Matsuda

    2000-06-01

    A model equation that describes the propagation of sound beams in a fluid is developed using the oblate spheroidal coordinate system. This spheroidal beam equation (SBE) is a parabolic equation and has a specific application to a theoretical prediction on focused, high-frequency beams from a circular aperture. The aperture angle does not have to be small. The theoretical background is basically along the same analytical lines as the composite method (CM) reported previously [B. Ystad and J. Berntsen, Acustica 82, 698-706 (1996)]. Numerical examples are displayed for the amplitudes of sound pressure along and across the beam axis when sinusoidal waves are radiated from the source with uniform amplitude distribution. The primitive approach to linear field analysis is readily extended to the case where harmonic generation in finite-amplitude sound beams becomes significant due to the inherent nonlinearity of the medium. The theory provides the propagation and beam pattern profiles that differ from the CM solution for each harmonic component.

  3. Multi story

    DEFF Research Database (Denmark)

    Law, Ho; Stelter, Reinhard

    2010-01-01

    The article discusses the use of narrative coaching as a powerful tool of co-creation and collaboration of the coach and client that emphasizes values and aspirations. Narrative coaches listen to the stories of lived experience and help clients identify values and skills. Narrative coaching has t...... central foundations which are societal/cultural and learning. The approach consists of the techniques of externalizing conversations and re-authoring and remembering....

  4. Modeling of Atmospheric Flow Around a Coastal Cape: Lee Side Story

    CERN Document Server

    Perlin, Natalie

    2013-01-01

    The current research focuses on mesoscale dynamics of the atmospheric circulation around an idealized coastal cape representing typical summertime circulation along the northwest coast of the U.S., studied using a mesoscale coupled ocean-atmosphere modeling system. The orographic wind maximum features a strong NW flow extending a few hundred kilometers downstream and seaward of the cape, which closely follows mesoscale orographic low pressure developed in the lee of the cape. Both wind maximum and the lee trough experience a pronounced diurnal cycle, marked by maximum northwest flow and minimum pressure in the local evening hours (its opposite phase during morning hours), and confirmed by observations from limited buoy and coastal stations. Vertical structure of the atmospheric boundary layer over the coastal ocean on the lee side of the cape indicated the downward propagation of potential temperature and wind features during the course of the day, as opposed to the traditional surface-driven development of t...

  5. Dynamic FE simulation of four-story steel frame modeled by solid elements and its validation using results of full-scale shake-table test

    OpenAIRE

    Miyamura, Tomoshi; Yamashita, Takuzo; AKIBA,HIROSHI; Ohsaki, Makoto

    2015-01-01

    Dynamic finite element analyses of a four-story steel building frame modeled as a fine mesh of solid elements are performed using E-Simulator, which is a parallel finite element analysis software package for precisely simulating collapse behaviors of civil and building structures. E-Simulator is under development at the National Research Institute for Earth Science and Disaster Prevention (NIED), Japan. A full-scale shake-table test for a four-story frame was conducted using E-Defense at NIED...

  6. Toy Story

    DEFF Research Database (Denmark)

    Cole, Anne Jodon; Petersson Brooks, Eva

    2016-01-01

    Toys are considered to be children’s cultural objects, yet when placed in a toy museum context they become a collection for adult viewing. This article uses Kress and van Leeuwens’ concept of ‘semiotic landscape’ wherein the exhibit provides a specific context of communication that becomes...... a mediating device between adults and children. The question then becomes, how does a display of static toys speak to a child’s culture of play? Through interviews with toy museum curators and personal observations it was found that the exhibition was designed to have adults share and reflect stories about...

  7. Effective Reading and Writing Instruction: A Focus on Modeling

    Science.gov (United States)

    Regan, Kelley; Berkeley, Sheri

    2012-01-01

    When providing effective reading and writing instruction, teachers need to provide explicit modeling. Modeling is particularly important when teaching students to use cognitive learning strategies. Examples of how teachers can provide specific, explicit, and flexible instructional modeling is presented in the context of two evidence-based…

  8. Narrative Comprehension and Story Grammar

    Directory of Open Access Journals (Sweden)

    Mehwish Zahoor

    2013-09-01

    Full Text Available Every text has an underlying structure which has a vital contribution in making it a meaningful whole. Awareness of a text’s structure therefore is significant in developing an overall sense of the text. Story grammar offers a simple and effective framework to analyze a coherent structure in narrative texts, hence is assumed to facilitate the comprehension of narratives. The research has been designed to be a descriptive study, with the objective to explain and illustrate how story grammar functions in constructing and decoding meanings in a narrative text, and, to highlight its scope in pedagogy. A short story text has been randomly selected from the short story collection in the English text book by Punjab text book board for Intermediate level. A three stepped comprehensive analysis of the sample text has been done by implementing the selected story grammar model. It has been found that story grammar helped in deriving coherent structure and meanings from the selected short story text; hence it has pedagogical implications in developing narrative comprehension.

  9. Proposal for product development model focused on ce certification methodology

    Directory of Open Access Journals (Sweden)

    Nathalia Marcia Goulart Pinheiro

    2015-09-01

    Full Text Available This paper presents a critical analysis comparing 21 product development models in order to identify whether these structures meet the demands Product Certification of the European Community (CE. Furthermore, it presents a product development model, comprising the steps in the models analyzed, including improvements in activities for referred product certification. The proposed improvements are justified by the growing quest for the internationalization of products and processes within companies.

  10. From Focus on Price to the Pyramid of Innovation, Information, Cooperation, Value and Trust: A Success Story of Five Swedish Building Material Manufacturers

    Directory of Open Access Journals (Sweden)

    Jan Sundquist

    2010-07-01

    Full Text Available This is a reprint from vol 8 no 2 which has not previously beeen available electronically.In the building sector, value for the customer, is often regarded as being value for money and this, in turn, is achieved by means of competitive tendering. However, there are companies that also focus on innovation as a competitive parameter in their contribution; hereafter referred to as innovative companies. Five managing directors from innovative companies in Sweden were interviewed about how innovation is dealt with in their respective companies. As well as the importance of information, this study points to two additional important factors for innovation, namely cooperation with a carefully chosen partner and the transference of values to the employees. Those innovative companies made careful choices and use means of information, cooperation, value and vision to create innovation in order to build trust for the company and for its products and services.

  11. Rabbi: exploring the inner world through stories

    Energy Technology Data Exchange (ETDEWEB)

    Umaschi, M. [MIT Media Lab., Cambridge, MA (United States)

    1996-12-31

    In the oral tradition, stories were told by the elder sages in order to give indirect advice. Today most stories are told in order to entertain. While some research on storytelling systems has focused on drama/theater metaphors and adventure/mystery simulation games, my research emphasizes the counseling and self-awareness possibilities of storytelling.

  12. The Time Is Right to Focus on Model Organism Metabolomes

    NARCIS (Netherlands)

    Edison, Arthur; Hall, Robert; Junot, Christophe; Karp, Peter; Kurland, Irwin; Mistrik, Robert; Reed, Laura; Saito, Kazuki; Salek, Reza; Steinbeck, Christoph; Sumner, Lloyd; Viant, Mark

    2016-01-01

    Model organisms are an essential component of biological and biomedical research that can be used to study specific biological processes. These organisms are in part selected for facile experimental study. However, just as importantly, intensive study of a small number of model organisms yields

  13. A model of visual, aesthetic communication focusing on web sites

    DEFF Research Database (Denmark)

    Thorlacius, Lisbeth

    2002-01-01

    design. With a point of departure in Roman Jakobson's linguistic communication model, the reader is introduced to a model which covers the communication aspects, the visual aspects, the aesthetic aspects and the net specific aspects of the analysis of media products. The aesthetic aspects rank low...

  14. Adventurers, Flaneurs, and Agitators: Travel Stories as Means for Marking and Transgressing Boundaries in 19th and Early 20th Century Finland

    Directory of Open Access Journals (Sweden)

    Kirsti Salmi-Niklander

    2014-12-01

    Full Text Available The article focuses on border crossings in travel stories, which were published in hand-written newspapers in 19th- and early 20th-century Finland. These papers were a popular tradition in student organizations and popular movements. Border crossings appear in travel stories in three different representations. Firstly, border crossings are repeated motifs in travel stories, both as challenging events and as small gestures and encounters. Travel stories demarcate boundaries, but they also provide a means for transgressing them. Secondly, hand-written newspapers as a literary practice highlight borders between oral and written communication. They were produced as one single manuscript copy, and published by being read out aloud in social events. Thirdly, the authors of hand-written newspapers were placed on the border of different positions in society such as class, gender and age. My analysis is based on the methodological discussion of small stories and personal experience narratives; travel stories can be defined as "local event narratives". I have outlined four basic models for travel stories which emerge from hand-written newspapers: the great mission story, the grand tour story, the flaneur story and the retreat story. The analysis of travel stories is presented through four different case studies with a time range from the 1850s to the 1920s: these materials have been produced in two provincial student fraternities (osakunta, in the temperance society "Star" in Helsinki in the 1890s, and in the Social Democratic Youth Club in the small industrial town of Karkkila in the 1910s and the 1920s. Many parallel features can be observed in travel stories, even though the social background and ideology of the authors are quite different. Time and space are important aspects in travel stories, and they often demarcate boundaries of class and gender.

  15. Toy Story

    DEFF Research Database (Denmark)

    Cole, Anne Jodon; Petersson Brooks, Eva

    2016-01-01

    Toys are considered to be children’s cultural objects, yet when placed in a toy museum context they become a collection for adult viewing. This article uses Kress and van Leeuwens’ concept of ‘semiotic landscape’ wherein the exhibit provides a specific context of communication that becomes...... a mediating device between adults and children. The question then becomes, how does a display of static toys speak to a child’s culture of play? Through interviews with toy museum curators and personal observations it was found that the exhibition was designed to have adults share and reflect stories about...... the toys with children. Such activity reflects a representation of toys as collections for adults (child’s perspective) rather than the playthings of children (children’s perspectives). Material culture of children was implicitly represented through playful, sensory, and affective engagement. Key words...

  16. Efficiently parallelized modeling of tightly focused, large bandwidth laser pulses

    CERN Document Server

    Dumont, Joey; Lefebvre, Catherine; Gagnon, Denis; MacLean, Steve

    2016-01-01

    The Stratton-Chu integral representation of electromagnetic fields is used to study the spatio-temporal properties of large bandwidth laser pulses focused by high numerical aperture mirrors. We review the formal aspects of the derivation of diffraction integrals from the Stratton-Chu representation and discuss the use of the Hadamard finite part in the derivation of the physical optics approximation. By analyzing the formulation we show that, for the specific case of a parabolic mirror, the integrands involved in the description of the reflected field near the focal spot do not possess the strong oscillations characteristic of diffraction integrals. Consequently, the integrals can be evaluated with simple and efficient quadrature methods rather than with specialized, more costly approaches. We report on the development of an efficiently parallelized algorithm that evaluates the Stratton-Chu diffraction integrals for incident fields of arbitrary temporal and spatial dependence. We use our method to show that t...

  17. Regulatory odour model development: Survey of modelling tools and datasets with focus on building effects

    DEFF Research Database (Denmark)

    Olesen, H. R.; Løfstrøm, P.; Berkowicz, R.;

    dispersion models for estimating local concentration levels in general. However, the report focuses on some particular issues, which are relevant for subsequent work on odour due to animal production. An issue of primary concern is the effect that buildings (stables) have on flow and dispersion. The handling...... of building effects is a complicated problem, and a major part of the report is devoted to the treatment of building effects in dispersion models...

  18. Sleep and Obesity: A focus on animal models

    Science.gov (United States)

    Mavanji, Vijayakumar; Billington, Charles J.; Kotz, Catherine M.; Teske, Jennifer A.

    2012-01-01

    The rapid rise in obesity prevalence in the modern world parallels a significant reduction in restorative sleep (Agras et al., 2004; Dixon et al., 2007; Dixon et al., 2001; Gangwisch and Heymsfield, 2004; Gupta et al., 2002; Sekine et al., 2002; Vioque et al., 2000; Wolk et al., 2003). Reduced sleep time and quality increases the risk for obesity, but the underlying mechanisms remain unclear (Gangwisch et al., 2005; Hicks et al., 1986; Imaki et al., 2002; Jennings et al., 2007; Moreno et al., 2006). A majority of the theories linking human sleep disturbances and obesity rely on self-reported sleep. However, studies with objective measurements of sleep/wake parameters suggest a U-shaped relationship between sleep and obesity. Studies in animal models are needed to improve our understanding of the association between sleep disturbances and obesity. Genetic and experimenter-induced models mimicking characteristics of human obesity are now available and these animal models will be useful in understanding whether sleep disturbances determine propensity for obesity, or result from obesity. These models exhibit weight gain profiles consistently different from control animals. Thus a careful evaluation of animal models will provide insight into the relationship between sleep disturbances and obesity in humans. In this review we first briefly consider the fundamentals of sleep and key sleep disturbances, such as sleep fragmentation and excessive daytime sleepiness (EDS), observed in obese individuals. Then we consider sleep deprivation studies and the role of circadian alterations in obesity. We describe sleep/wake changes in various rodent models of obesity and obesity resistance. Finally, we discuss possible mechanisms linking sleep disturbances with obesity. PMID:22266350

  19. Can classic moral stories promote honesty in children?

    Science.gov (United States)

    Lee, Kang; Talwar, Victoria; McCarthy, Anjanie; Ross, Ilana; Evans, Angela; Arruda, Cindy

    2014-08-01

    The classic moral stories have been used extensively to teach children about the consequences of lying and the virtue of honesty. Despite their widespread use, there is no evidence whether these stories actually promote honesty in children. This study compared the effectiveness of four classic moral stories in promoting honesty in 3- to 7-year-olds. Surprisingly, the stories of "Pinocchio" and "The Boy Who Cried Wolf" failed to reduce lying in children. In contrast, the apocryphal story of "George Washington and the Cherry Tree" significantly increased truth telling. Further results suggest that the reason for the difference in honesty-promoting effectiveness between the "George Washington" story and the other stories was that the former emphasizes the positive consequences of honesty, whereas the latter focus on the negative consequences of dishonesty. When the "George Washington" story was altered to focus on the negative consequences of dishonesty, it too failed to promote honesty in children.

  20. Preparing Secondary Mathematics Teachers: A Focus on Modeling in Algebra

    Science.gov (United States)

    Jung, Hyunyi; Mintos, Alexia; Newton, Jill

    2015-01-01

    This study addressed the opportunities to learn (OTL) modeling in algebra provided to secondary mathematics pre-service teachers (PSTs). To investigate these OTL, we interviewed five instructors of required mathematics and mathematics education courses that had the potential to include opportunities for PSTs to learn algebra at three universities.…

  1. Integrating Emotion-Focused Therapy with the Satir Model

    Science.gov (United States)

    Brubacher, Lorrie

    2006-01-01

    The experiential humanistic family systems approach of Virginia Satir lacks a theoretical structure and is thus vulnerable to losing its experiential nature and being reduced to a mere collection of creative techniques. A way to effectively keep Satir's transformative presence alive is to integrate her approach with a model that is solidly…

  2. Integrating Emotion-Focused Therapy with the Satir Model

    Science.gov (United States)

    Brubacher, Lorrie

    2006-01-01

    The experiential humanistic family systems approach of Virginia Satir lacks a theoretical structure and is thus vulnerable to losing its experiential nature and being reduced to a mere collection of creative techniques. A way to effectively keep Satir's transformative presence alive is to integrate her approach with a model that is solidly…

  3. Stories from the field.

    Science.gov (United States)

    Caine, Julie; Pokhrel, Kabi

    2011-11-01

    "Stories From the Field" is a series of short profiles of tobacco control programs and their leaders, showcasing promising technical assistance and training models in Louisiana, Puerto Rico, the Cherokee Nation, West Virginia, the Pacific Islands, and the Virgin Islands. The series illuminates key themes of collaboration with diverse stakeholders, elimination of health disparities, building tobacco control coalitions, engaging youth to reduce commercial tobacco use, sustaining tobacco control efforts, and the use of the media to raise public awareness that are highlighted in the Health Promotion Practice Supplement Theme Issue, Training and Technical Assistance: Lessons Learned to Sustain Social Norm Changes in Tobacco Control. Common tobacco control strategies bind the stories together. Local knowledge, coalition building, community involvement, innovative partnerships, and educational outreach are at the core of all of these tobacco control projects.

  4. Efficiently parallelized modeling of tightly focused, large bandwidth laser pulses

    Science.gov (United States)

    Dumont, Joey; Fillion-Gourdeau, François; Lefebvre, Catherine; Gagnon, Denis; MacLean, Steve

    2017-02-01

    The Stratton-Chu integral representation of electromagnetic fields is used to study the spatio-temporal properties of large bandwidth laser pulses focused by high numerical aperture mirrors. We review the formal aspects of the derivation of diffraction integrals from the Stratton-Chu representation and discuss the use of the Hadamard finite part in the derivation of the physical optics approximation. By analyzing the formulation we show that, for the specific case of a parabolic mirror, the integrands involved in the description of the reflected field near the focal spot do not possess the strong oscillations characteristic of diffraction integrals. Consequently, the integrals can be evaluated with simple and efficient quadrature methods rather than with specialized, more costly approaches. We report on the development of an efficiently parallelized algorithm that evaluates the Stratton-Chu diffraction integrals for incident fields of arbitrary temporal and spatial dependence. This method has the advantage that its input is the unfocused field coming from the laser chain, which is experimentally known with high accuracy. We use our method to show that the reflection of a linearly polarized Gaussian beam of femtosecond duration off a high numerical aperture parabolic mirror induces ellipticity in the dominant field components and generates strong longitudinal components. We also estimate that future high-power laser facilities may reach intensities of {10}24 {{W}} {{cm}}-2.

  5. Sex Differences in Animal Models: Focus on Addiction.

    Science.gov (United States)

    Becker, Jill B; Koob, George F

    2016-04-01

    The purpose of this review is to discuss ways to think about and study sex differences in preclinical animal models. We use the framework of addiction, in which animal models have excellent face and construct validity, to illustrate the importance of considering sex differences. There are four types of sex differences: qualitative, quantitative, population, and mechanistic. A better understanding of the ways males and females can differ will help scientists design experiments to characterize better the presence or absence of sex differences in new phenomena that they are investigating. We have outlined major quantitative, population, and mechanistic sex differences in the addiction domain using a heuristic framework of the three established stages of the addiction cycle: binge/intoxication, withdrawal/negative affect, and preoccupation/anticipation. Female rats, in general, acquire the self-administration of drugs and alcohol more rapidly, escalate their drug taking with extended access more rapidly, show more motivational withdrawal, and (where tested in animal models of "craving") show greater reinstatement. The one exception is that female rats show less motivational withdrawal to alcohol. The bases for these quantitative sex differences appear to be both organizational, in that estradiol-treated neonatal animals show the male phenotype, and activational, in that the female phenotype depends on the effects of gonadal hormones. In animals, differences within the estrous cycle can be observed but are relatively minor. Such hormonal effects seem to be most prevalent during the acquisition of drug taking and less influential once compulsive drug taking is established and are linked largely to progesterone and estradiol. This review emphasizes not only significant differences in the phenotypes of females and males in the domain of addiction but emphasizes the paucity of data to date in our understanding of those differences. Copyright © 2016 by The American Society

  6. Classroom Management of Children with Emotional and Behavioral Disorders. A Storied Model: Torey Hayden's One Child

    Science.gov (United States)

    Marlowe, Mike; Disney, Gayle; Wilson, Kayce Jo

    2004-01-01

    Torey Hayden's style of classroom management in her nonfiction book "One Child" was examined. "One Child" unfolds within the space of a special education classroom for children with severe behavioral impairments and focuses on Sheila, a troubled 6-year-old, who has tied a 3-year-old boy to a tree and critically burned him. Each technique Hayden…

  7. Blogger, stick to your story: Modeling topical noise in blogs with coherence measures

    NARCIS (Netherlands)

    J. He; W. Weerkamp; M. Larson; M. de Rijke

    2008-01-01

    Topical noise in blogs arises when bloggers digress from the central topical thrust of their blogs. We introduce a method to explicitly incorporate a model of topical noise into a language modeling approach to the task of blog distillation. Topical noise is integrated into the model using a coherenc

  8. The moderating role of regulatory focus on the social modeling of food intake.

    Science.gov (United States)

    Florack, Arnd; Palcu, Johanna; Friese, Malte

    2013-10-01

    Regulatory focus theory proposes two distinct modi of self-regulation, a promotion focus and a prevention focus. According to this theory, individuals in a prevention focus apply behavioral strategies to successfully avoid unpleasant outcomes and maintain a safe and secure state. By contrast, individuals in a promotion focus apply behavioral strategies to realize pleasant outcomes and to advance the current state. Applied to the context of eating behavior, regulatory focus theory suggests that individuals in a prevention focus should be especially sensitive to avoid socially inappropriate eating behavior. A way to ensure socially appropriate eating behavior is to follow social models. In the present research, we therefore tested the assumption that a prevention focus leads to stronger modeling effects in eating behavior than a promotion focus. In two studies, we manipulated individual's self-regulation states by putting individuals in a state of reflection about their hopes and aspirations (promotion focus) vs. a state of reflection about their duties and responsibilities (prevention focus). Participants then observed the consumption behavior of a second participant who either consumed or did not consume offered food (Study 1) or received incidental information about the amount of food an ostensible previous participant had consumed (Study 2). Across both studies, participants in a prevention focus matched their food consumption more closely to that of a present (Study 1) and not-present social model (Study 2), compared to participants in a promotion focus. The results advance our understanding of modeling effects in food intake by showing the importance of regulatory orientations.

  9. Telling Stories

    Science.gov (United States)

    Mathematics Teaching, 2010

    2010-01-01

    Every year the Institute of Mathematics Pedagogy meet for a residential conference in July working together to focus on particular aspects of teaching and learning mathematics. The conference is open to all, and includes all sorts of people involved in mathematics and education. This year the focus was on proof and narrative. This article looks at…

  10. The Pieter Schippers story : Almost 40 years of developments in sonar performance modelling in the Netherlands

    NARCIS (Netherlands)

    Schippers, P.; Colin, M.E.G.D.; Beerens, S.P.

    2014-01-01

    This paper is dedicated to the work of Pieter Schippers and gives an overview of his achievement in sonar performance modelling over his career. This publication is the last of a long list, many of which published at UDT [1-5]. A historical review is presented of the sonar performance modeling work

  11. Modeling of a focused beam in a semi-infinite highly scattering medium

    DEFF Research Database (Denmark)

    Tycho, Andreas

    1999-01-01

    with confocal microscopy by focusing the probing beam. It istherefore interesting to gauge the performance of the Extended-HuygensFresnel theory for a geometry with a focused gaussian beam against a (fortissue) more well established model such as diffusion theory. A new modelof a focused beam in a semi...

  12. Story asides as a useful construct in examining adults' story recall.

    Science.gov (United States)

    Bluck, Susan; Alea, Nicole; Baron-Lee, Jacqueline M; Davis, Danielle K

    2016-02-01

    Older adults sometimes exhibit higher levels of off-target verbosity during story recall than do young adults. This appears as the inclusion of extraneous information not directly relevant to the topic. Some production of such material has been clearly related to cognitive decline, particularly older adults' inability to inhibit production of irrelevant information. In tandem, however, research also suggests that some extraneous information is indirectly related to the topic and may reflect age differences in communicative styles. To further elucidate the social-cognitive aspect of this issue, the question of import is: What is the content of the additional information provided by participants during story recall? The present study answers this question. Grounded in the autobiographical memory and life story literatures, we introduce the construct, story asides, and a reliable content-analytic scheme for its assessment. Young and older adults (N = 129) recalled 1 of 2 types of stories: a personal autobiographical memory or an experimenter-generated fictional story. Narratives were reliably coded for story asides. As expected, older adults produced more story asides than young adults only for autobiographical stories. The discussion focuses on the role of story asides in everyday communication including the possibility that they may be a sign of communicative expertise.

  13. Hidden Stories, Toxic Stories, Healing Stories: The Power of Narrative in Peace and Reconciliation

    Directory of Open Access Journals (Sweden)

    Stephan Marks

    2011-01-01

    Full Text Available Research on narrative is more than simply listening to (more or less nice stories. There are stories that are hidden between the lines; these need to be noticed and retrieved. There are stories that can be toxic to be exposed to; these need to be coped with and conceived. But there may be stories that have a healing quality, too—stories that can contribute to peace and reconciliation. These three possible qualities of narratives are the focus of the following paper, which was delivered in October 2008, at the launch of the Centre for Interdisciplinary Research on Narrative at St. Thomas University in Fredericton, New Brunswick, Canada. The lecture was based on his interdisciplinary research project "Geschichte und Erinnerung" [History and Memory, www.geschichte-erinnerung.de] in which interviews with Nazi followers, bystanders, and perpetrators were conducted and analysed. Marks presented one of the key findings of this research—shame—and its effect on what the interviewees recounted, as well as its relevance for National Socialism and present-day German society.

  14. The USEtox story: A survey of model developer visions and user requirements

    DEFF Research Database (Denmark)

    Westh, Torbjørn Bochsen; Hauschild, Michael Zwicky; Birkved, Morten

    2015-01-01

    , we analyzed user expectations and experiences and compared them with the developers’ visions. Methods We applied qualitative and quantitative data collection methods including an online questionnaire, semistructured user and developer interviews, and review of scientific literature. Questionnaire...... in LCA and to provide global guidance for practitioners. Model developers show different perceptions of some underlying aspects including model transparency and expected user expertise. Users from various sectors and geographic regions apply USEtox mostly in research and for consulting. Questionnaire...... that understanding interactions between USEtox and its users helps guiding model development and dissemination. USEtox-specific recommendations are to (1) respect the application context for different user types, (2) provide detailed guidance for interpreting model and factors, (3) facilitate consistent integration...

  15. Cross-language linking of news stories on the web using interlingual topic modelling

    OpenAIRE

    De Smet, Wim; Moens, Marie-Francine

    2009-01-01

    We have studied the problem of linking event information across different languages without the use of translation systems or dictionaries. The linking is based on interlingua information obtained through probabilistic topic models trained on comparable corpora written in two languages (in our case English and Dutch). To achieve this goal, we expand the Latent Dirichlet Allocation model to process documents in two languages. We demonstrate the validity of the learned interlingual topics in a...

  16. Telling better stories: strengthening the story in story and simulation

    Science.gov (United States)

    Kemp-Benedict, Eric

    2012-12-01

    information available at that time, based on statements that appear in the SRES itself. The CIB method is a technique for constructing internally consistent qualitative scenarios. Global-scale scenario exercises, in particular climate scenarios, typically include both qualitative (narrative) and quantitative (model) elements. As noted by Schweizer and Kriegler, the dominant method for such studies, which Alcamo (2001, 2008) formalized and named the 'story and simulation' (SAS) approach, relies at least in part on quantitative modeling to ensure consistency. Schweizer and Kriegler rightly criticize the idea that models alone can ensure consistency of a scenario narrative. By itself, this critique is not new. Indeed, if asked, both Alcamo and Raskin et al (Raskin et al 2005), whom Schweizer and Kriegler (2012) cite, would probably agree with them; both sources emphasize the need for qualitative storylines that go beyond what models can provide. However, Schweizer and Kriegler correctly point out that these sources provide little or no guidance to those responsible for the narratives beyond a dialog with the model outputs. The CIB method addresses this problem, and Schweizer and Kriegler's application of the method shows that even the best narrative-writing teams can benefit from this guidance. While the paper of Schweizer and Kriegler makes a compelling argument for using CIB in global scenarios, it should be used in combination with other methods. A scenario exercise has several aims, of which consistency is one. Another important goal is diversity: given a set of internally consistent scenarios, a diverse set covers the space of possibilities, and thereby helps users of the scenarios avoid underestimating or overestimating the potential for change in one or another key factor (e.g., see (Carlsen 2009)). From this point of view, the SRES authors could legitimately respond to Schweizer and Kriegler's finding that the SRES scenarios excluded interesting variants on coal

  17. The USEtox story: A survey of model developer visions and user requirements

    DEFF Research Database (Denmark)

    Westh, Torbjørn Bochsen; Hauschild, Michael Zwicky; Birkved, Morten;

    2015-01-01

    expertise to integrate sound revision and update procedures and to facilitate modularity, data import/export, and incorporation into relevant software and databases during model design and development. Our fully documented approach can inspire performing similar surveys on other LCA-related tools......, we analyzed user expectations and experiences and compared them with the developers’ visions. Methods We applied qualitative and quantitative data collection methods including an online questionnaire, semistructured user and developer interviews, and review of scientific literature. Questionnaire...... into LCA software and methods, (4) improve update/testing procedures, (5) strengthen communication between developers and users, and (6) extend model scope. By generalizing our recommendations to guide scientific model development in a broader context, we emphasize to acknowledge different levels of user...

  18. Telling the Human Story.

    Science.gov (United States)

    Richardson, Miles

    1987-01-01

    Proposes that one of the fundamental human attributes is telling stories. Explores the debate on whether Neanderthals possessed language ability. Discusses the role of the "human story" in teaching anthropology. (DH)

  19. A Plot Story:The Ransom of Red Chief

    Institute of Scientific and Technical Information of China (English)

    WANG Si-yu

    2015-01-01

    The Ransom of Red Chief is a short story written by O · Henry. Some critics regard it as a plot story but some do not. A typical plot story should focus on the plot:using techniques such as flashback or foreshadowing to unfold the plot and containing exposition, complication, climax, resolution, conclusion to rich the plot. The main characters are presented with internal and ex⁃ternal conflicts as well. In this thesis, a detailed analysis will be presented to prove that this story is really a plot story.

  20. Story Parsing Grammar

    Institute of Scientific and Technical Information of China (English)

    张松懋

    1994-01-01

    Story understanding is one of the important branches of natural language understanding research in AI techniques.A new approach to story understanding is proposed in this paper.The so-called Story Parsing Grammar (SPG) is used to represent the story abstracting processes with different degrees in story understanding,and the story understanding process is converted to the storyn recognizing process done by the syntactic parser of SPG.This kind of story understanding is called story parsing.In this paper,firstly,a survey of story understanding research is given.Secondly,by the classification of various kinds of story structures,the so-called Case Frame Forest (CFF) is proposed to represent the superficial meaning of story.Based on CFF,a high-dimen-sional grammar,called Forest Grammar (FG),is defined.Furthermore,SPG is defined as a subclass of context-sensitive FG.Considering the context-sensitivity of story content,a type of context-sensitive derivation is defined in the definition of SPG.Lastly,data about runtime efficiency of the syntactic parsing algorithm of weak precedence SPG,a subclass of SPG,are given and analysed.

  1. Story Book Science

    Science.gov (United States)

    Enfield, Mark; Mathew, Eliza

    2012-01-01

    Young children love stories, and teachers love to read stories. Young children also love to explore the motion of objects--they watch tossed balls, observe objects rolling down ramps, and are mesmerized by spinning tops. Yet it can be challenging to integrate these two loves, stories and exploring motion, in one lesson. Furthermore, while children…

  2. Comparing Ethical Content Ratings of Text and Video Versions of Stories

    Science.gov (United States)

    Gomberg, Anna; Orlova, Darya; Squillace, Mary; Narvaez, Darcia

    2005-01-01

    The Rating Ethical Content System (RECS) provides a systematic method for rating the positive content of stories, based on the Four Process model of ethical behavior (Rest, 1983): ethical sensitivity, ethical judgment, ethical focus and ethical action. We present data from an experiment in which college students and children rated the ethical…

  3. From Subhiksha (Prosper To Iksha (Perspire: The Topsy-Turvy Story of Indian Retail Business Model

    Directory of Open Access Journals (Sweden)

    H. M.J. Bidyarthi

    2010-01-01

    Full Text Available Problem statement: To examine the factors that led to inception, high growth and sudden closure of Indian business ventures in upcoming sectors in a short span of less than 10 years. Approach: An IITian and an IIM-A grad (India’s top notch academic institution set up one of the largest Indian retail chain named Subhiksha Trading services Pvt. Ltd. in 1997 on an Indian business model that opened 1600 outlets in 10 years time across the country and proved a great hit for others to follow suit. This was based on the estimated $350 billion Indian retail market of which organized retail accounts for only 6% of the total market. Suddenly it found itself cash strapped heading for closure of its outlets and perspiring for obtaining funds to revive it. It left many lessons for Indian organized retail sector to draw which this study attempted to bring forth. Results: The debt financers raised their eye brows against Subhiksha’s enterpreneur and a debt restructuring plan is ensuing to revive it indicating severe deficiency in the capitalization plan of Subhiksha. Conclusion: The management of an organization must never oversight its invigorating weaknesses when the growth occurs rapidly during its introduction stage itself on account of favorable circumstances in the environment. The case of Subhiksha studied here is an illustrative lesson of failure of a sound business model due to this oversight.

  4. Vision in Multiple Sclerosis (MS): The Story, Structure-Function Correlations, and Models for Neuroprotection

    Science.gov (United States)

    Sakai, Reiko E.; Feller, Daniel J.; Galetta, Kristin M.; Galetta, Steven L.; Balcer, Laura J.

    2012-01-01

    Visual dysfunction is one of the most common clinical manifestations of multiple sclerosis (MS). Just over a decade ago, MS clincial trials did not include visual outcomes but experts recognized the need for more senstive measures of visual function. Low-contrast letter acuity emerged as the leading candidate to measure visual disability in MS and subsequent studies found low-contrast acuity testing to correlate well with brain MRI lesion burden, visual-evoked potentials (VEPs), quality of life (QOL), and retinal nerve fiber layer (RNFL) loss as measured by optical coherence tomography (OCT). OCT in MS has allowed for assessment of structure-funciton correlations that make the anterior visual pathway and acute optic neuritis (ON) ideal models for testing novel agents for neuroprotection and repair. New therapies that reduce axonal loss by neuroprotective or myelin repair mechanisms can now be assessed non-invasively by OCT and coupled with visual function data. Based on OCT studies in MS, RNFL thickness is reduced significantly among patients (92 µm) versus controls (105 µm), and is particularly reduced in MS eyes with a history of ON (85 µm). Worsening of visual function by a clinically significant ≥7 letters or ~1.5 lines for low-contrast acuity is associated with approximately 4.5 µm reductions in RNFL thickness in MS eyes. Longitudinal studies of OCT have also shown RNFL axonal loss over time that occurs even in the absence of acute ON, and that correlates with clincially meaningful worsening of vision and QOL, even in patients with benign MS. The latest OCT investigations involve high-resolution spectral-domain (SD) OCT with segmentation and measurement of specific retinal layers using computerized algorithms. These methods allow quantitation of ganglion cell (neuronal) layer loss as well as axonal degeneration in MS in vivo. In this review, we examine the data from these studies and ongoing trials that highlight the entity of ON as a model to

  5. Minimalism in the modern short story

    Directory of Open Access Journals (Sweden)

    A Razi

    2009-09-01

    Full Text Available Short story has recently become the focus of attention in the late decades in Iran. The expanding value of writing short story is actually a reasonable outcome of the dominance of minimalism- a movement which is based upon simplicity and shortness. Minimalist writers, leaving out redundant features of narration, mainly focus on essentialities through applying a variety of techniques such as cuttings from the interesting moments of real life, evading introduction, applying inter-referents, choice of words, short stanzas and sentences and so on. Looking upon critic’s opinion about such a tendency over the past and present, this article will come up with a brief explanation of the properties of such stories. Finally a sample story “candles will never go dead” will be analyzed and discussed in the lights of such techniques.

  6. Window Stories

    DEFF Research Database (Denmark)

    Hauge, Bettina

    strategies for overheating or to communicate with people in a more user informed way. The people participating in the study lived in different houses and had different backgrounds. They were involved in the project over a period of 3-4 months. The prolonged participation was facilitated through a variety......, as well as the opposite. The report also includes a special focus on overheating and people’s strategies against this. Knowing about what people appreciate in a window and their actual practices and the reasons for their behaviour may be useful in many different ways, for instance to inform public...

  7. Weak Precedence Story Parsing Grammar

    Institute of Scientific and Technical Information of China (English)

    张松懋

    1995-01-01

    Story understanding is one of the important branches of natural language understanding research in AI techniques.The story understanding approach based on Story Parsing Grammar (SPG) involves that SPG is used to represent different abstracting processes of stories with different levels in story understanding and that the story understanding process is converted to the recognition process of stories using the syntactic parser of SPG.This kind of story understanding is called story parsing.In this paper,firstly a subclass of SPG,called Weak Precedence SPG(WPSPG),is defined.Afterwards the syntactic parsing algorithm of WPSPG is studied.An example of story parsing is also given.

  8. Focusing properties of Gaussian Schell-model beams by an astigmatic aperture lens

    Institute of Scientific and Technical Information of China (English)

    Pan Liu-Zhan; Ding Chao-Liang

    2007-01-01

    This paper studies the focusing properties of Gaussian Schell-model (GSM) beams by an astigmatic aperture lens.It is shown that the axial irradiance distribution, the maximum axial irradiance and its position of focused GSM beams by an astigmatic aperture lens depend upon the astigmatism of the lens, the coherence of partially coherent light, the truncation parameter of the aperture and Fresnel number. The numerical calculation results are given to illustrate how these parameters affect the focusing property.

  9. Jane Addams, Stories, and Imagination

    Science.gov (United States)

    Griffith, Susan C.

    2009-01-01

    Early twentieth-century social activist Jane Addams is best known for her work at Hull House, the settlement house she founded with Ellen Gates Starr in 1889. Adams was also a pacifist, storyteller, writer and philosopher. Through her actions, stories, and writing, Addams modeled a philosophy of democracy-in-action based in imagination and…

  10. Jane Addams, Stories, and Imagination

    Science.gov (United States)

    Griffith, Susan C.

    2009-01-01

    Early twentieth-century social activist Jane Addams is best known for her work at Hull House, the settlement house she founded with Ellen Gates Starr in 1889. Adams was also a pacifist, storyteller, writer and philosopher. Through her actions, stories, and writing, Addams modeled a philosophy of democracy-in-action based in imagination and…

  11. Fairytales and Stories in the Waldorf Kindergarten

    OpenAIRE

    JANEČKOVÁ, Pavla

    2012-01-01

    The bachelor thesis shows how storytelling is treated in the Waldorf approach to pre-primary education. In the theoretical part, it examines the historical development of stories and tales, the value of their pictorial language and their interpretation. It also discusses the methodological principles used in the Waldorf approach and the guidelines for selecting particular stories. The empirical part focuses on the influence of storytelling on children, namely on the social climate of the clas...

  12. Jan. 25 ( Story of a Girl )

    OpenAIRE

    Ramadan, Hadeel M

    2015-01-01

    The work presented in this thesis explores the possibility to integrate two dimensional drawings with three dimensional animated characters in 3D computer graphics. The goal was to preserve the effects of the cartoonish artistic style and produce a strong emotional and moving story without realistic animation feel. Inspiration of the storyboard was based on a true story from the Arab Spring events that occurred in several Arab countries, I focused my work on the context of Egypt. MFA

  13. Designing a bone health and soy focus group discussion guide based on the health belief model

    Science.gov (United States)

    Focus groups were used to assess the knowledge and skills of women in order to support curricula development. The Health Belief Model was applied to the discussion guide to enhance focus group findings and applications. Constructs related to perceived susceptibility, severity, benefits, and barriers...

  14. A Donor-Focused Fundraising Model: An Essential Tool in Community College Foundations' Toolkit

    Science.gov (United States)

    Carter, Linnie S.

    2011-01-01

    The increased focus on private fundraising poses challenges for community colleges (Jackson & Glass, 2000). A challenge is a lack of fundraising experience within community colleges and their foundations. There now exists a donor-focused fundraising model for community colleges to use to enhance their fundraising initiatives and increase the…

  15. Testing Cognitive and Emotion-Focused Models of Worry in Black and White Samples.

    Science.gov (United States)

    Kertz, Sarah J; Bakhti, Rinad; Stevens, Kimberly T; Curewitz, Alana

    2015-01-01

    Several models have been proposed to conceptualize worry. Broadly, the models can be classified as cognitive (including the Avoidance Model, the Intolerance of Uncertainty Model, and the Metacognitive Model) and emotion-focused (including Emotion Dysregulation and Acceptance-Based models). Although these models have received strong empirical investigation in primarily non-Hispanic White samples, no known study has examined the applicability to racial and ethnic minority groups. The current study compared the proportion of variance explained by cognitive and emotion-focused models of worry in White and Black samples. Results indicated that cognitive and emotion-focused models significantly predicted worry in both Black and White samples. However, the overall amount of variance in worry explained by the models was less for Black samples. Specifically, controlling for gender, the cognitive models explained 53% of the variance in worry in the White sample compared with 19% in the Black sample. Similarly, the emotion-focused models explained 34% of the variance in worry in the White sample but only 13% in the Black sample. These findings suggest that well-established conceptual frameworks for worry failed to explain the bulk of the variance in worry in Black samples, leaving much unknown. Additional research is needed to identify key variables that may further explain worry in ethnic minority samples.

  16. A third generation object-oriented process model:roles and architectures in focus

    OpenAIRE

    Kivistö, K. (Kari)

    2000-01-01

    Abstract This thesis examines and evaluates the Object-Oriented Client/Server (OOCS) model, a process model that can be used when IT organizations develop object-oriented client/server applications. In particular, it defines the roles in the development team and combines them into the process model. Furthermore, the model focuses on the client/server architecture, considering it explicitly. The model has been under construction for several years and it has been test...

  17. Historical short stories as nature of science instruction in secondary science classrooms: Science teachers' implementation and students' reactions

    Science.gov (United States)

    Reid-Smith, Jennifer Ann

    This study explores the use of historical short stories as nature of science (NOS) instruction in thirteen secondary science classes. The stories focus on the development of science ideas and include statements and questions to draw students' and teachers' attention to key NOS ideas and misconceptions. This study used mixed methods to examine how teachers implement the stories, factors influencing teachers' implementation, the impact on students' NOS understanding, students' interest in the stories and factors correlated with their interest. Teachers' implementation decisions were influenced by their NOS understanding, curricula, time constraints, perceptions of student ability and resistance, and student goals. Teachers implementing stories at a high-level of effectiveness were more likely to make instructional decisions to mitigate constraints from the school environment and students. High-level implementers frequently referred to their learning goals for students as a rationale for implementing the stories even when facing constraints. Teachers implementing at a low-level of effectiveness were more likely to express that constraints inhibited effective implementation. Teachers at all levels of implementation expressed concern regarding the length of the stories and time required to fully implement the stories. Additionally, teachers at all levels of implementation expressed a desire for additional resources regarding effective story implementation and reading strategies. Evidence exists that the stories can be used to improve students' NOS understanding. However, under what conditions the stories are effective is still unclear. Students reported finding the stories more interesting than textbook readings and many students enjoyed learning about scientists and the development of science idea. Students' interest in the stories is correlated with their attitudes towards reading, views of effective science learning, attributions of academic success, and interest in

  18. Toy Stories: Modeling Rates

    Science.gov (United States)

    Swanson, Patricia E.

    2015-01-01

    Elementary school mathematics is increasingly recognized for its crucial role in developing the foundational skills and understandings for algebra. In this article, the author uses a lesson to introduce the concept of "rates"--comparing two different types and units of measure--and how to graph them. Described is the lesson and shared…

  19. The impact of culture and employee-focused criteria on productivity: A structural equation modelling approach

    Science.gov (United States)

    Ab Hamid, Mohd Rashid; Mustafa, Zainol; Mohd Suradi, Nur Riza; Idris, Fazli; Abdullah, Mokhtar

    2013-04-01

    Culture and employee-focused criteria are important factors for the success of any organization. These factors have to be aligned with the productivity initiatives in the organization in order to gear ahead for excellence. Therefore, this article investigated the impact of culture and employee-focused criteria on productivity in Higher Education Institutions (HEIs) in Malaysia using intangible indicators through core values. The hypothesized relationship was tested using Structural Equation Modeling (SEM) with the PLS estimation technique. 429 questionnaires were returned from the target population. The results of the modelling revealed that the PLS estimation confirmed all the hypotheses tested as in the hypothesized model. The results generally support significant relationships between culture values, employee-focused values and productivity-focused values. The study also confirmed the mediating role of employee-focused values for the relationship between culture values and productivity-focused values. In conclusion, the empirically validated results supported the adequacy of the hypothezised model of the impact of culture and employee-focused criteria on productivity in HEI through value-based indicators.

  20. The Story of Chocolate

    Institute of Scientific and Technical Information of China (English)

    王希玲

    2004-01-01

    American-made chocolates and cocoa products number in the hundreds1. There hides a fascinating2 story behind this wonderful product. To tell that story and provide a better understanding of the chocolate industry and its long-standing traditions is the purpose of this article. The Story of Chocolate is essentially a layman's3 introduction to the subject. It will provide readers an opportunity to view the industry as a whole4.

  1. My Story: Real Stories of People Living with Thalassemia

    Science.gov (United States)

    ... Share Compartir Real Stories from People living with Thalassemia On this Page Rahul’s Story Aaron’s Story Rahul’s ... is Rahul Kapoor, and I was born with thalassemia, a blood disorder which requires transfusions every other ...

  2. A Model for Ubiquitous Serious Games Development Focused on Problem Based Learning

    Science.gov (United States)

    Dorneles, Sandro Oliveira; da Costa, Cristiano André; Rigo, Sandro José

    2015-01-01

    The possibility of using serious games with problem-based learning opens up huge opportunities to connect the experiences of daily life of students with learning. In this context, this article presents a model for serious and ubiquitous games development, focusing on problem based learning methodology. The model allows teachers to create games…

  3. Modeling of Nonlinear Propagation in Multi-layer Biological Tissues for Strong Focused Ultrasound

    Institute of Scientific and Technical Information of China (English)

    FAN Ting-Bo; LIU Zhen-Bo; ZHANG Zhe; ZHANG DONG; GONG Xiu-Fen

    2009-01-01

    A theoretical model of the nonlinear propagation in multi-layered tissues for strong focused ultrasound is proposed. In this model, the spheroidal beam equation (SBE) is utilized to describe the nonlinear sound propagation in each layer tissue, and generalized oblique incidence theory is used to deal with the sound transmission between two layer tissues. Computer simulation is performed on a fat-muscle-liver tissue model under the irradiation of a 1 MHz focused transducer with a large aperture angle of 35°. The results demonstrate that the tissue layer would change the amplitude of sound pressure at the focal region and cause the increase of side petals.

  4. Focused information criterion and model averaging based on weighted composite quantile regression

    KAUST Repository

    Xu, Ganggang

    2013-08-13

    We study the focused information criterion and frequentist model averaging and their application to post-model-selection inference for weighted composite quantile regression (WCQR) in the context of the additive partial linear models. With the non-parametric functions approximated by polynomial splines, we show that, under certain conditions, the asymptotic distribution of the frequentist model averaging WCQR-estimator of a focused parameter is a non-linear mixture of normal distributions. This asymptotic distribution is used to construct confidence intervals that achieve the nominal coverage probability. With properly chosen weights, the focused information criterion based WCQR estimators are not only robust to outliers and non-normal residuals but also can achieve efficiency close to the maximum likelihood estimator, without assuming the true error distribution. Simulation studies and a real data analysis are used to illustrate the effectiveness of the proposed procedure. © 2013 Board of the Foundation of the Scandinavian Journal of Statistics..

  5. A focus area maturity model for a statewide master person index.

    Science.gov (United States)

    Duncan, Jeffrey; Xu, Wu; Narus, Scott P; Clyde, Stephen; Nangle, Barry; Thornton, Sid; Facelli, Julio

    2013-01-01

    The sharing of personally identifiable information across organizational boundaries to facilitate patient identification in Utah presents significant policy challenges. Our objective was to create a focus area maturity model to describe and evaluate our progress in developing a policy framework to support a statewide master person index (sMPI) for healthcare and public health operations and research in Utah. We used various artifacts, including minutes from policy guidance committee meetings over a span of 18 months, a report from Utah's Digital Health Services Commission, and a draft technical requirements document to retrospectively analyze our work and create a focus area maturity model describing the domain of policy needed to support the sMPI. We then used our model to assess our progress and future goals. The focus area maturity model provides an orderly path that can guide the complex process of developing a functional statewide master person index among diverse, autonomous partners. While this paper focuses on our experience in Utah, we believe that the arguments for using a focus area maturity model to guide the development of state or regional MPIs is of general interest.

  6. A Focus Area Maturity Model for a Statewide Master Person Index

    Science.gov (United States)

    Duncan, Jeffrey; Xu, Wu; Narus, Scott P.; Clyde, Stephen; Nangle, Barry; Thornton, Sid; Facelli, Julio

    2013-01-01

    Objective: The sharing of personally identifiable information across organizational boundaries to facilitate patient identification in Utah presents significant policy challenges. Our objective was to create a focus area maturity model to describe and evaluate our progress in developing a policy framework to support a statewide master person index (sMPI) for healthcare and public health operations and research in Utah. Materials and Methods: We used various artifacts, including minutes from policy guidance committee meetings over a span of 18 months, a report from Utah’s Digital Health Services Commission, and a draft technical requirements document to retrospectively analyze our work and create a focus area maturity model describing the domain of policy needed to support the sMPI. We then used our model to assess our progress and future goals. Conclusions: The focus area maturity model provides an orderly path that can guide the complex process of developing a functional statewide master person index among diverse, autonomous partners. While this paper focuses on our experience in Utah, we believe that the arguments for using a focus area maturity model to guide the development of state or regional MPIs is of general interest. PMID:23923093

  7. Vibration Stabilization of a Mechanical Model of a X-Band Linear Collider Final Focus Magnet

    Energy Technology Data Exchange (ETDEWEB)

    Frisch, Josef; Chang, Allison; Decker, Valentin; Doyle, Eric; Eriksson, Leif; Hendrickson, Linda; Himel, Thomas; Markiewicz, Thomas; Partridge, Richard; Seryi, Andrei; /SLAC

    2006-09-28

    The small beam sizes at the interaction point of a X-band linear collider require mechanical stabilization of the final focus magnets at the nanometer level. While passive systems provide adequate performance at many potential sites, active mechanical stabilization is useful if the natural or cultural ground vibration is higher than expected. A mechanical model of a room temperature linear collider final focus magnet has been constructed and actively stabilized with an accelerometer based system.

  8. Generalized Empirical Likelihood-Based Focused Information Criterion and Model Averaging

    Directory of Open Access Journals (Sweden)

    Naoya Sueishi

    2013-07-01

    Full Text Available This paper develops model selection and averaging methods for moment restriction models. We first propose a focused information criterion based on the generalized empirical likelihood estimator. We address the issue of selecting an optimal model, rather than a correct model, for estimating a specific parameter of interest. Then, this study investigates a generalized empirical likelihood-based model averaging estimator that minimizes the asymptotic mean squared error. A simulation study suggests that our averaging estimator can be a useful alternative to existing post-selection estimators.

  9. When's a story not at story?

    DEFF Research Database (Denmark)

    Christensen, Eva

    the social field. The notion ‘story’ here refers to the telling of what occurred according to the teller, ending with the telling of the punchline (see Sacks, 1974 and 1992, vol II, pp.478-482). ‘Narrative’ refers to a more extended unit of actions including also the participants’ evaluation of the reported...... events (e.g. Labov & Waletzky, 1967; Ochs, 1997). Using oral narratives collected from tourist guides, group discussions, meetings and interviews, it will be shown how stories referring to the same historical event are told almost identically regarding structure, but whose function in context differs....... For example, as presented in this paper, a tourist guide tells the same story about a violent motorcycle gang, part of her ancetdotal reportoire, during two guided tours. The story is fixed in content and structure, but when brought into social interaction with tourists, it becomes part of a broader narrative...

  10. Karuk Stories #2.

    Science.gov (United States)

    Bennett, Ruth, Ed.; And Others

    Three illustrated stories from the Karuk Indians of northwestern California are told in free English translation and in Karuk with literal English translation. English and Karuk Unifon alphabet charts are provided. Stories tell of seasonal migration of the mockingbird and the swamp robin, coyote's quest for the sun and how he determined the sun's…

  11. Fragmented Work Stories

    DEFF Research Database (Denmark)

    Humle, Didde Maria; Reff Pedersen, Anne

    2015-01-01

    by exploring how different types of fragmentation create meanings. This is done by studying the work stories of job and personnel consultants and by drawing on the results of a narrative, ethnographic study of a consultancy. The analysis demonstrates how work stories are social practices negotiated, retold...

  12. Tell Them a Story.

    Science.gov (United States)

    Jennings, Maude M.; And Others

    1990-01-01

    Introduces the work of Eula Lee, a fictional storyteller and the feminist author's alter ego. Encourages teachers at all educational levels to become storytellers for the magic of the story itself, the instructional strength of metaphor, and the personal power of interpretation and presentation. Stresses the stories' ability to reinforce community…

  13. Everybody Has a Story

    DEFF Research Database (Denmark)

    The book bears witness of Young peoples lived lives across Europe, Russia and Japan. It contains stories about love, loss of love and loss of loved ones, about dreams of future lives and wonders of lives as such. And it tells stories about bullying, mental illness and simple strives just to be able...

  14. From 'solution shop' model to 'focused factory' in hospital surgery: increasing care value and predictability.

    Science.gov (United States)

    Cook, David; Thompson, Jeffrey E; Habermann, Elizabeth B; Visscher, Sue L; Dearani, Joseph A; Roger, Veronique L; Borah, Bijan J

    2014-05-01

    The full-service US hospital has been described organizationally as a "solution shop," in which medical problems are assumed to be unstructured and to require expert physicians to determine each course of care. If universally applied, this model contributes to unwarranted variation in care, which leads to lower quality and higher costs. We purposely disrupted the adult cardiac surgical practice that we led at Mayo Clinic, in Rochester, Minnesota, by creating a "focused factory" model (characterized by a uniform approach to delivering a limited set of high-quality products) within the practice's solution shop. Key elements of implementing the new model were mapping the care process, segmenting the patient population, using information technology to communicate clearly defined expectations, and empowering nonphysician providers at the bedside. Using a set of criteria, we determined that the focused-factory model was appropriate for 67 percent of cardiac surgical patients. We found that implementation of the model reduced resource use, length-of-stay, and cost. Variation was markedly reduced, and outcomes were improved. Assigning patients to different care models increases care value and the predictability of care process, outcomes, and costs while preserving (in a lesser clinical footprint) the strengths of the solution shop. We conclude that creating a focused-factory model within a solution shop, by applying industrial engineering principles and health information technology tools and changing the model of work, is very effective in both improving quality and reducing costs.

  15. Fifteen minute stories about training.

    Science.gov (United States)

    Crowther, Catherine; Wiener, Jan; Tserashchuk, Alena; Tsivinsky, Vladimir; Volodina, Elena; Alexandrova, Natalia L

    2011-11-01

    This panel presentation at the Journal's conference in St Petersburg responded to the conference theme of 'Ancestors in Personal, Professional and Social History' by relating it to the experience of training and being trained on the IAAP 'router' programme in Russia. The two organizers of the programme (JW and CC) have worked in Russia for over 12 years, bringing analysts from Britain to Moscow and St Petersburg on a 'shuttle' basis as supervisors and personal analysts. A few months after handing over the router programme in December 2010 to the Russian colleagues they had trained, they invited four analysts, three Russian and one Belarusian, to tell a short personal story about their training, linking it to the theme of 'the Ancestors'. The resulting four stories are very different but complement each other, using imagery to illustrate issues concerning both value and ambivalence. JW and CC jointly wrote their story about the programme in response to the four stories, reflecting on some of their themes and from them, giving consideration to the flexibility and limits of such a model of cross-cultural training. Themes in the stories included the possibility of mutual adaptation to another culture without losing tradition and identity; moving on from doctrinaire Soviet attitudes in education to embrace 'not knowing'; both organizers and routers learning from mistakes and from joint experience without guilt or shame; the need to protect reflective space amidst the constraints of time and geography. All Russian and UK contributors could finally acknowledge their shared luck to find themselves in the right place at the right time to respond to the collective revival of psychoanalytic practice in Russia.

  16. Story Re-Visions: Tales for the Future.

    Science.gov (United States)

    Gray, Jacqueline W.

    Over the years many different psychologists and psychoanalysts have found value in the concept of the self-narrative, or the "life story." Narrative thought demands an appreciation of the particulars of time and place and a focus on multidimensional understanding of events, people, emotion, and motivation. By using the life story or…

  17. Person Focused Training: A Model for Delivering Positive Behavioural Supports to People with Challenging Behaviours

    Science.gov (United States)

    McClean, B.; Dench, C.; Grey, I.; Shanahan, S.; Fitzsimons, E.; Hendler, J.; Corrigan, M.

    2005-01-01

    Person Focused Training is introduced as a model of service delivery for people with severe challenging behaviours. It is defined as training and supporting staff to conduct functional assessments and to design and implement positive behavioural support for specific individuals with challenging behaviours. Longitudinal outcome data are presented…

  18. An Agent-Based Model of Status Construction in Task Focused Groups

    NARCIS (Netherlands)

    Grow, André; Flache, Andreas; Wittek, Rafael

    2015-01-01

    Status beliefs link social distinctions, such as gender and race, to assumptions about competence and social worth. Recent modeling work in status construction theory suggests that interactions in small, task focused groups can lead to the spontaneous emergence and diffusion of such beliefs in large

  19. Formulating state space models in R with focus on longitudinal regression models

    DEFF Research Database (Denmark)

    Dethlefsen, Claus; Lundbye-Christensen, Søren

      We provide a language for formulating a range of state space models. The described methodology is implemented in the R -package sspir available from cran.r-project.org . A state space model is specified similarly to a generalized linear model in R , by marking the time-varying terms in the form......  We provide a language for formulating a range of state space models. The described methodology is implemented in the R -package sspir available from cran.r-project.org . A state space model is specified similarly to a generalized linear model in R , by marking the time-varying terms...

  20. Methods and Strategies: Oral Science Stories. Using Culturally Responsive Storytelling to Teach Socioeconomically Disadvantaged Students

    Science.gov (United States)

    Harris, Renard; Hall, Cynthia; Hawkins, Tristan; Hartley, Megan; McCray, Willie; Sirleaf, Hammed

    2016-01-01

    T.A.L.E.S., Teaching And Learning with Engaging Stories, is an alternative teaching method that focuses on enhancing learning by teaching science, math, ELA, and social studies through story. A six-week research study investigating socioeconomically disadvantaged students' responses to oral stories was conducted during an afterschool tutoring…

  1. Forming "Connections" and Awakening "Visions": Using Short Story Collections in the Classroom.

    Science.gov (United States)

    Lesesne, Teri S.

    1994-01-01

    Discusses how some recent short story collections written for young adults can make studying the genre exciting and interesting for students. Describes how teachers can awaken new vision within students by using the short story in the literature classroom. Focuses on stories written especially for adolescents. (HB)

  2. Using Social Stories for Students on the Autism Spectrum: Teacher Perspectives

    Science.gov (United States)

    Dev, Poonam C.

    2014-01-01

    Stories in one form or another have been used for thousands of years to influence social behaviour. A social story is a short story created specifically for an individual with an autism spectrum disorder (ASD) and focuses on social skills (e.g. initiating conversations) that need to be developed for him or her or on helping the individual adjust…

  3. Experimentally validated multiphysics computational model of focusing and shock wave formation in an electromagnetic lithotripter.

    Science.gov (United States)

    Fovargue, Daniel E; Mitran, Sorin; Smith, Nathan B; Sankin, Georgy N; Simmons, Walter N; Zhong, Pei

    2013-08-01

    A multiphysics computational model of the focusing of an acoustic pulse and subsequent shock wave formation that occurs during extracorporeal shock wave lithotripsy is presented. In the electromagnetic lithotripter modeled in this work the focusing is achieved via a polystyrene acoustic lens. The transition of the acoustic pulse through the solid lens is modeled by the linear elasticity equations and the subsequent shock wave formation in water is modeled by the Euler equations with a Tait equation of state. Both sets of equations are solved simultaneously in subsets of a single computational domain within the BEARCLAW framework which uses a finite-volume Riemann solver approach. This model is first validated against experimental measurements with a standard (or original) lens design. The model is then used to successfully predict the effects of a lens modification in the form of an annular ring cut. A second model which includes a kidney stone simulant in the domain is also presented. Within the stone the linear elasticity equations incorporate a simple damage model.

  4. The Disarming Seduction of Stories.

    Science.gov (United States)

    Hoy, Pat C., II

    2001-01-01

    Contends that essays are the proper rhetorical domain of stories, the place where stories most naturally belong when they are being used for the development and enlargement of ideas. Notes that stories are so powerful and distracting that when used together to make a familiar story, they can divert attention away from the essay's idea. Concludes…

  5. Formulating state space models in R with focus on longitudinal regression models

    DEFF Research Database (Denmark)

    Dethlefsen, Claus; Lundbye-Christensen, Søren

    2006-01-01

    We provide a language for formulating a range of state space models with response densities within the exponential family. The described methodology is implemented in the R-package sspir. A state space model is specified similarly to a generalized linear model in R, and then the time-varying terms...

  6. Modelling of the internal dynamics and density in a tens of joules plasma focus device

    Energy Technology Data Exchange (ETDEWEB)

    Marquez, Ariel [CNEA and Instituto Balseiro, 8402 Bariloche (Argentina); Gonzalez, Jose [INVAP-CONICET and Instituto Balseiro, 8402 Bariloche, Argentina. (Argentina); Tarifeno-Saldivia, Ariel; Pavez, Cristian; Soto, Leopoldo [CCHEN, Comision Chilena de Energia Nuclear, Casilla 188-D, Santiago (Chile); Center for Research and Applications in Plasma Physics and Pulsed Power, P4 (Chile); Clausse, Alejandro [CNEA-CONICET and Universidad Nacional del Centro, 7000 Tandil (Argentina)

    2012-01-15

    Using MHD theory, coupled differential equations were generated using a lumped parameter model to describe the internal behaviour of the pinch compression phase in plasma focus discharges. In order to provide these equations with appropriate initial conditions, the modelling of previous phases was included by describing the plasma sheath as planar shockwaves. The equations were solved numerically, and the results were contrasted against experimental measurements performed on the device PF-50J. The model is able to predict satisfactorily the timing and the radial electron density profile at the maximum compression.

  7. Refinement of a discontinuity-free edge-diffraction model describing focused wave fields.

    Science.gov (United States)

    Sedukhin, Andrey G

    2010-03-01

    Two equivalent forms of a refined discontinuity-free edge-diffraction model describing the structure of a stationary focused wave field are presented that are valid in the framework of the scalar Debye integral representation for a diffracted rotationally symmetric converging spherical wave of a limited yet not-too-low angular opening. The first form describes the field as the sum of a direct quasi-spherical wave and a plurality of edge quasi-conical waves of different orders, the optimum discontinuity-free angular spectrum functions of all the waves being dependent on the polar angle only. According to the second form, the focused field is fully characterized by only three components--the same quasi-spherical wave and two edge quasi-conical waves of the zero and first order, of which the optimum discontinuity-free angular spectrum functions are dependent on both the polar angle and the polar radius counted from the geometrical focus.

  8. Finite thickness lens model for self-focusing (defocusing) in Kerr medium

    Institute of Scientific and Technical Information of China (English)

    Shi-fang GUO; Qiang TIAN

    2009-01-01

    A "finite thickness lens" model for self-focusing (defocusing) in Kerr medium is presented. An onaxis normalization transmittance formula is presented for arbitrary nonlinear phase shift for the finite thickness Kerr medium by introducing a nonlinear ABCD-matrix for the transition of a Gaussian beam from linear to nonlinear medium, without complex calculation for the beam radius at the far field aperture. The variation of the peak and valley transmittance difference is found to enhance linearly as the phase shift at the focus increases by increasing the thickness of the medium. If the ratio of the Rayleigh distance divided by the thickness of the medium (d/zo) is constant and small enough, the peak and valley transmittance difference stays constant. Finally, a qualitative formula is presented to express the relationship between the system parameters and the on-axis phase shift at the focus.

  9. Pilot study of Creating Change, a new past-focused model for PTSD and substance abuse.

    Science.gov (United States)

    Najavits, Lisa M; Johnson, Kay M

    2014-01-01

    Creating Change (CC) is a new past-focused behavioral therapy model developed for comorbid posttraumatic stress disorder (PTSD) and substance use disorder (SUD). It was designed to address current gaps in the field, including the need for a past-focused PTSD/SUD model that has flexibility, can work with complex clients, responds to the staffing and resource limitations of SUD and other community-based treatment programs, can be conducted in group or individual format, and engages clients and clinicians. It was designed to follow the style, tone, and format of Seeking Safety, a successful present-focused PTSD/SUD model. CC can be used in conjunction with SS and/or other models if desired. We conducted a pilot outcome trial of the model with seven men and women outpatients diagnosed with current PTSD and SUD, who were predominantly minority and low-income, with chronic PTSD and SUD. Assessments were conducted pre- and post-treatment. Significant improvements were found in multiple domains including some PTSD and trauma-related symptoms (eg, dissociation, anxiety, depression, and sexual problems); broader psychopathology (eg, paranoia, psychotic symptoms, obsessive symptoms, and interpersonal sensitivity); daily life functioning; cognitions related to PTSD; coping strategies; and suicidal ideation (altogether 19 variables, far exceeding the rate expected by chance). Effect sizes were consistently large, including for both alcohol and drug problems. No adverse events were reported. Despite study methodology limitations, CC is promising. Clients can benefit from past-focused therapy that addresses PTSD and SUD in integrated fashion. © American Academy of Addiction Psychiatry.

  10. Researcher Story: Stuttering

    Science.gov (United States)

    ... Have a Question In the News Researcher Story: Stuttering In a 2010 movie, The King’s Speech, many ... effects of the disorder. How Do Researchers Study Stuttering? Video of How Do Researchers Study Stuttering? A ...

  11. Researcher Story: Stuttering

    Medline Plus

    Full Text Available ... Doctor Science Education Resources Community Resources Clear Health A–Z Publications List More » Search Health Topics Quick ... Clinical Research Trials and You The Basics Finding a Clinical Trial List of Registries Personal Stories For ...

  12. Building our stories

    DEFF Research Database (Denmark)

    2017-01-01

    Tourism transforms people and places. New stakeholders are emerging, landscapes of power are shifting, and lines of responsibilities are being redrawn. Everyday stories of coping, success, empowerment, nurturing, relationship building and activism are important tools for reflection and learning...

  13. Telling stories: keeping secrets.

    Science.gov (United States)

    Jensen, Joan M

    2009-01-01

    This article addresses the reticence of some farm women to share their experiences with historians and how that desire to keep secrets collides with the desire by scholars to tell the stories of these women. It argues that scholars must continue to struggle with the issue of which stories to tell publicly and which to keep private. The author discusses her own experience telling stories about rural women in the 1970s and the need to give voice to the heritage of rural women, especially of groups that have feared revealing their experiences. She offers examples of historians of rural women who have successfully worked with formerly silenced populations and urges historians to continue to tell stories about these lives, to reevaluate what has been already learned, to ask new questions, and to discuss which secrets need to be shared.

  14. Evaluation of approaches focused on modelling of organic carbon stocks using the RothC model

    Science.gov (United States)

    Koco, Štefan; Skalský, Rastislav; Makovníková, Jarmila; Tarasovičová, Zuzana; Barančíková, Gabriela

    2014-05-01

    The aim of current efforts in the European area is the protection of soil organic matter, which is included in all relevant documents related to the protection of soil. The use of modelling of organic carbon stocks for anticipated climate change, respectively for land management can significantly help in short and long-term forecasting of the state of soil organic matter. RothC model can be applied in the time period of several years to centuries and has been tested in long-term experiments within a large range of soil types and climatic conditions in Europe. For the initialization of the RothC model, knowledge about the carbon pool sizes is essential. Pool size characterization can be obtained from equilibrium model runs, but this approach is time consuming and tedious, especially for larger scale simulations. Due to this complexity we search for new possibilities how to simplify and accelerate this process. The paper presents a comparison of two approaches for SOC stocks modelling in the same area. The modelling has been carried out on the basis of unique input of land use, management and soil data for each simulation unit separately. We modeled 1617 simulation units of 1x1 km grid on the territory of agroclimatic region Žitný ostrov in the southwest of Slovakia. The first approach represents the creation of groups of simulation units based on the evaluation of results for simulation unit with similar input values. The groups were created after the testing and validation of modelling results for individual simulation units with results of modelling the average values of inputs for the whole group. Tests of equilibrium model for interval in the range 5 t.ha-1 from initial SOC stock showed minimal differences in results comparing with result for average value of whole interval. Management inputs data from plant residues and farmyard manure for modelling of carbon turnover were also the same for more simulation units. Combining these groups (intervals of initial

  15. Stories Under Your Feet

    DEFF Research Database (Denmark)

    Riesto, Svava; Støvring, Jan

    2014-01-01

    Review of the new Købmagergade design by Karres et Brandts and Polyform. The article discusses the new design, its uses and story-telling, seen in relation to the "urban space boom" in Copenhagen of the early 2000nds.......Review of the new Købmagergade design by Karres et Brandts and Polyform. The article discusses the new design, its uses and story-telling, seen in relation to the "urban space boom" in Copenhagen of the early 2000nds....

  16. Model of small-scale self-focusing and spatial noise in high power laser driver

    Institute of Scientific and Technical Information of China (English)

    HU; Wei(胡巍); FU; Xiquan(傅喜泉); YU; Song; (喻松); GUO; Hong(郭弘)

    2002-01-01

    A linearization model was used to analyze the laser beam propagation in a high power laser driver and the influence of the small-scale self-focusing and spatial phase noise on beam quality in disk amplifiers. The quantitative relations between intensities of spatial phase noise, B-integral, and beam intensity contrast in near field are given explicitly. A spectrum specification of phase noise has been obtained by setting a limit to the contrast of an output beam.

  17. Focused shape models for hip joint segmentation in 3D magnetic resonance images.

    Science.gov (United States)

    Chandra, Shekhar S; Xia, Ying; Engstrom, Craig; Crozier, Stuart; Schwarz, Raphael; Fripp, Jurgen

    2014-04-01

    Deformable models incorporating shape priors have proved to be a successful approach in segmenting anatomical regions and specific structures in medical images. This paper introduces weighted shape priors for deformable models in the context of 3D magnetic resonance (MR) image segmentation of the bony elements of the human hip joint. The fully automated approach allows the focusing of the shape model energy to a priori selected anatomical structures or regions of clinical interest by preferentially ordering the shape representation (or eigen-modes) within this type of model to the highly weighted areas. This focused shape model improves accuracy of the shape constraints in those regions compared to standard approaches. The proposed method achieved femoral head and acetabular bone segmentation mean absolute surface distance errors of 0.55±0.18mm and 0.75±0.20mm respectively in 35 3D unilateral MR datasets from 25 subjects acquired at 3T with different limited field of views for individual bony components of the hip joint.

  18. A modeling approach for district heating systems with focus on transient heat transfer in pipe networks

    DEFF Research Database (Denmark)

    Mohammadi, Soma; Bojesen, Carsten

    2015-01-01

    finite element method is applied to simulate transient temperature changes in pipe networks. The model is calculating time series data related to supply temperature to the DHN from heat production units, heat loads and return temperature related to each consumer to calculate dynamic temperature changes...... district heating networks [DHN] characteristics. This paper is presenting a new developed model, which reflects the thermo-dynamic behavior of DHN. It is designed for tree network topologies. The purpose of the model is to serve as a basis for applying a variety of scenarios towards lowering...... the temperature in DH systems. The main focus is on modeling transient heat transfer in pipe networks regarding the time delays between the heat supply unit and the consumers, the heat loss in the pipe networks and the consumers’ dynamic heat loads. A pseudo-dynamic approach is adopted and also the implicit...

  19. APPLYING THE EFQM EXCELLENCE MODEL AT THE GERMAN STUDY LINE WITH FOCUS ON THE CRITERION

    Directory of Open Access Journals (Sweden)

    ILIES LIVIU

    2013-07-01

    Full Text Available This article presents a stage of the implementation process of the EFQM Model in a higher education institution, namely at the German study line within the Faculty of Economics and Business Administration, “Babeș - Bolyai” University, Cluj –Napoca. Actually, designing this model for the higher education sector means highlighting the basis for the implementation of a Total Quality Management model, seen as a holistic dimension for the perception of quality in an organization. By means of the EFQM method, the authors try to identify the performance degree of the criterion ,,Customer Results”, related to the students’ satisfaction level. The students are seen as primary customers of the higher education sector and have an essential role in defining the quality dimensions. On the one hand, the customers of the higher education sector can surface the status quo of the quality in the institution and on the other hand they can improve the quality. Actually, the continuous improvement of quality is highly linked to performance. From this point of view, the European Foundation for Quality Management model is a practical tool in order to support the analysis of the opportunities within higher education institutions. Therefore, this model offers a customer focused approach, because many higher education institutions consider the students to be the heart of teaching and researching. Further, the fundamental concepts are defined and the focus is pointed in the direction of customer approach, which highlight the idea that excellence is creating added value for customers. Anticipating and identifying the current and the future needs of the students by developing a balanced range of relevant dimensions and indicators means taking an appropriate action based on the holistic view of quality in an organization. Focusing and understanding students’ and other customers’ requirements, their needs and expectations, follows the idea that performance can

  20. Focused ultrasound for treatment of uterine myoma: From experimental model to clinical practice

    Directory of Open Access Journals (Sweden)

    Terzić Milan

    2008-01-01

    Full Text Available It is well known that focused ultrasound has a biologic effect on tissue. High intensity focused ultrasound (HIFU on a small target area raises the temperature of the tissue enough to denaturate proteins and cause irreversible cell damage. The tight focus of the ultrasound energy allows delivery of the intended dose to a very precise location. The resulting coagulation necrosis is relatively painless. The application of this method in the human clinical setting has required pilot studies on an animal model. Although the treatment had a high success rate, there was a significant percentage of complications, mainly attributed to the technical drawbacks of the procedure. Therefore, this method has been modified for use in humans, and the HIFU is now guided, monitored and controlled by magnetic resonance imaging (MRI. In October 2004, Food and Drug Adiministration (FDA approved MRI guided focused ultrasound treatment of uterine fibroids in humans. Since then, successful treatment of uterine myomas by HIFU has been performed in thousands of women.

  1. The tight focusing properties of Laguerre-Gaussian-correlated Schell-model beams

    Science.gov (United States)

    Xu, Hua-Feng; Zhang, Zhou; Qu, Jun; Huang, Wei

    2016-08-01

    Based on the Richards-Wolf vectorial diffraction theory, the tight focusing properties, including the intensity distribution, the degree of polarization and the degree of coherence, of the Laguerre-Gaussian-correlated Schell-model (LGSM) beams through a high-numerical-aperture (NA) focusing system are investigated in detail. It is found that the LGSM beam exhibits some extraordinary focusing properties, which is quite different from that of the GSM beam, and the tight focusing properties are closely related to the initial spatial coherence ? and the mode order n. The LGSM beam can form an elliptical focal spot, a circular focal spot or a doughnut-shaped dark hollow beam at the focal plane by choosing a suitable value of the initial spatial coherence ?, and the central dark size of the dark hollow beam increases with the increase of the mode order n. In addition, the influences of the initial spatial coherence ? and the mode order n on the degree of polarization and the degree of coherence are also analysed in detail, respectively. Our results may find applications in optical trapping.

  2. Generalized focus point and mass spectra comparison of highly natural SUGRA GUT models

    CERN Document Server

    Baer, Howard; Savoy, Michael

    2016-01-01

    Supergravity grand unified models (SUGRA GUTs) are highly motivated and allow for a high degree of electroweak naturalness when the superpotential parameter mu~ 100-300 GeV (preferring values closer to 100 GeV). We first illustrate that models with radiatively-driven naturalness enjoy a generalized focus-point behavior wherein all soft terms are correlated instead of just scalar masses. Next, we generate spectra from four SUGRA GUT archetypes: 1. SO(10) models where the Higgs doublets live in different 10-dimensional irreducible representations (irreps), 2. models based on SO(10) where the Higgs multiplets live in a single 10-dimensional irrep but with D-term scalar mass splitting, 3. models based on SU(5) and 4. a more general SUGRA model with 12 independent parameters. Electroweak naturalness implies for all models a spectrum of light higgsinos with m(higgsinos)< 300 GeV and gluinos with m(gluino)< 2-4 TeV. However, masses and mixing in the third generation sfermion sector differ distinctly between th...

  3. Climate Model Diagnostic and Evaluation: With a Focus on Satellite Observations

    Science.gov (United States)

    Waliser, Duane

    2011-01-01

    Each year, we host a summer school that brings together the next generation of climate scientists - about 30 graduate students and postdocs from around the world - to engage with premier climate scientists from the Jet Propulsion Laboratory and elsewhere. Our yearly summer school focuses on topics on the leading edge of climate science research. Our inaugural summer school, held in 2011, was on the topic of "Using Satellite Observations to Advance Climate Models," and enabled students to explore how satellite observations can be used to evaluate and improve climate models. Speakers included climate experts from both NASA and the National Oceanic and Atmospheric Administration (NOAA), who provided updates on climate model diagnostics and evaluation and remote sensing of the planet. Details of the next summer school will be posted here in due course.

  4. Vascular disease modeling using induced pluripotent stem cells: Focus in Hutchinson-Gilford Progeria Syndrome.

    Science.gov (United States)

    Pitrez, P R; Rosa, S C; Praça, C; Ferreira, L

    2016-05-06

    Induced pluripotent stem cells (iPSCs) represent today an invaluable tool to create disease cell models for modeling and drug screening. Several lines of iPSCs have been generated in the last 7 years that changed the paradigm for studying diseases and the discovery of new drugs to treat them. In this article we focus our attention to vascular diseases in particular Hutchinson-Gilford Progeria Syndrome (HGPS), a devastating premature aging disease caused by a mutation in the lamin A gene. In general, patients die because of myocardial infarction or stroke. Because the patients are fragile the isolation of a particular type of cells is very difficult. Therefore in the last 5 years, researchers have used cells derived from iPSCs to model aspects of the HGPS and to screen libraries of chemicals to retard or treat the disease.

  5. A Comprehensive Fluid Dynamic-Diffusion Model of Blood Microcirculation with Focus on Sickle Cell Disease

    Science.gov (United States)

    Le Floch, Francois; Harris, Wesley L.

    2009-11-01

    A novel methodology has been developed to address sickle cell disease, based on highly descriptive mathematical models for blood flow in the capillaries. Our investigations focus on the coupling between oxygen delivery and red blood cell dynamics, which is crucial to understanding sickle cell crises and is unique to this blood disease. The main part of our work is an extensive study of blood dynamics through simulations of red cells deforming within the capillary vessels, and relies on the use of a large mathematical system of equations describing oxygen transfer, blood plasma dynamics and red cell membrane mechanics. This model is expected to lead to the development of new research strategies for sickle cell disease. Our simulation model could be used not only to assess current researched remedies, but also to spur innovative research initiatives, based on our study of the physical properties coupled in sickle cell disease.

  6. Using stories to disseminate research: the attributes of representative stories.

    Science.gov (United States)

    Steiner, John F

    2007-11-01

    When researchers communicate their findings to patients, clinicians, policy-makers, or media, they may find it helpful to supplement quantitative data with stories about individuals who represent themes in their research. Whether such stories are gathered during the research itself or identified from other sources, researchers must develop strategies for assessing their representativeness. This paper proposes 5 attributes of representative stories: (1) expression of important themes in the research, (2) explicit location in the "distribution" of stories that exemplify the theme, (3) verifiability, (4) acknowledgment of uncertainty, and (5) compelling narration. This paper summarizes research on substance abuse among physicians, and uses these 5 attributes to assess the representativeness of a published case report and a fictional short story about addicted physicians. While neither story is fully representative of the research, the process of evaluating these stories illustrates an approach to identifying representative stories for use in disseminating research.

  7. Modeling Discontinuous Phase Transitions in Gel Membranes: Focus on Hysteresis and Feedback Mechanisms

    Science.gov (United States)

    Kuksenok, Olga

    Feedback mechanisms are vital in a number of processes in biological systems. For example, feedback loops play an essential role during a limb development in mammals and are responsible for the asymmetric cell division to constrain the growth in plants to the specific regions. An integration of well-controlled feedback loops into the fully synthetic materials is an important step in designing a range of biomimetic functionalities. Herein, we focus on hydrogels functionalized with light-sensitive trisodium salt of copper chlorophyllin and study discontinuous phase transitions in these systems. Prior experimental studies had shown that illumination of these functionalized gels results in their heating and in discontinuous, first order phase transition upon the variation in temperature. Herein, we develop the first computational model for these gels; the framework of the model is based on the gel Lattice Spring Model, in this work we account for the gel heating under the illumination. The results of our simulations are in a good agreement with prior experimental studies. We focus on pattern development during the volume phase transitions in membranes of various thicknesses and show that one can effectively utilize light intensity to remotely control feedback loops in these systems.

  8. Engaging Elements of Cancer-Related Digital Stories in Alaska.

    Science.gov (United States)

    Cueva, Melany; Kuhnley, Regina; Revels, Laura; Schoenberg, Nancy E; Lanier, Anne; Dignan, Mark

    2016-09-01

    The tradition of storytelling is an integral part of Alaska Native cultures that continues to be a way of passing on knowledge. Using a story-based approach to share cancer education is grounded in Alaska Native traditions and people's experiences and has the potential to positively impact cancer knowledge, understandings, and wellness choices. Community health workers (CHWs) in Alaska created a personal digital story as part of a 5-day, in-person cancer education course. To identify engaging elements of digital stories among Alaska Native people, one focus group was held in each of three different Alaska communities with a total of 29 adult participants. After viewing CHWs' digital stories created during CHW cancer education courses, focus group participants commented verbally and in writing about cultural relevance, engaging elements, information learned, and intent to change health behavior. Digital stories were described by Alaska focus group participants as being culturally respectful, informational, inspiring, and motivational. Viewers shared that they liked digital stories because they were short (only 2-3 min); nondirective and not preachy; emotional, told as a personal story and not just facts and figures; and relevant, using photos that showed Alaskan places and people.

  9. Operant alcohol self-administration in dependent rats: focus on the vapor model.

    Science.gov (United States)

    Vendruscolo, Leandro F; Roberts, Amanda J

    2014-05-01

    Alcoholism (alcohol dependence) is characterized by a compulsion to seek and ingest alcohol (ethanol), loss of control over intake, and the emergence of a negative emotional state during withdrawal. Animal models are critical in promoting our knowledge of the neurobiological mechanisms underlying alcohol dependence. Here, we review the studies involving operant alcohol self-administration in rat models of alcohol dependence and withdrawal with the focus on the alcohol vapor model. In 1996, the first articles were published reporting that rats made dependent on alcohol by exposure to alcohol vapors displayed increased operant alcohol self-administration during acute withdrawal compared with nondependent rats (i.e., not exposed to alcohol vapors). Since then, it has been repeatedly demonstrated that this model reliably produces physical and motivational symptoms of alcohol dependence. The functional roles of various systems implicated in stress and reward, including opioids, dopamine, corticotropin-releasing factor (CRF), glucocorticoids, neuropeptide Y (NPY), γ-aminobutyric acid (GABA), norepinephrine, and cannabinoids, have been investigated in the context of alcohol dependence. The combination of models of alcohol withdrawal and dependence with operant self-administration constitutes an excellent tool to investigate the neurobiology of alcoholism. In fact, this work has helped lay the groundwork for several ongoing clinical trials for alcohol dependence. Advantages and limitations of this model are discussed, with an emphasis on what future directions of great importance could be.

  10. MODELING AND SHIFTING FOCUS AS A FACILITATOR FOR INTENTIONAL EMERGENCE IN TRANSFORMATION DESIGN

    DEFF Research Database (Denmark)

    Nielsen, Louise Møller; Hansen, Poul H. Kyvsgård; Mabogunje, Ade

    2009-01-01

    In this paper we discuss the phenomenon "intentional emergence" in a transformation design context. We examine modeling and play enablers for intentional emergence and report on experiences with the Lego Serious Play method. The empirical observations are based on a real-time transformation design...... project called The Good Elderly Life, in which we focus on especially initial project scoping and problem investigations. Based on an analysis of video-material and interviews, we have found indications which suggest that intentional emergence - in relation to project scoping and problem investigation...

  11. Reading the Story of Jesus Christ as an Epic

    Institute of Scientific and Technical Information of China (English)

    Wangari Mwai; Edwin Gimode; Charles Kebaya

    2015-01-01

    There is no doubt that Jesus Christ is the eternal embodiment of the Christian faith. The story of salvation,especially the life of Jesus, forms the basis through which many Christians encounter the eternal. Indeed, each facetof Christ is intricately intertwined with the others and that Christian literature often focuses on redefining variousfigures in the image of Christ and on illustrating morality. Without disparaging in any way the story of Jesus Christ,this paper parallels the conceptualization of epic heroism and the narrative of Jesus Christ. In doing this, the articleprovides a critical exegesis of elements of epic heroism in the story of Christ. Ultimately, reading the story of JesusChrist through the prism of epic heroism helps us submit that it is a "tale of Christian identity" comparable to theepic identity and able to eonvey eternal meaning to Christian groups who recognize it as "their story of salvation".

  12. Modeling a Miniaturized Scanning Electron Microscope Focusing Column - Lessons Learned in Electron Optics Simulation

    Science.gov (United States)

    Loyd, Jody; Gregory, Don; Gaskin, Jessica

    2016-01-01

    This presentation discusses work done to assess the design of a focusing column in a miniaturized Scanning Electron Microscope (SEM) developed at the NASA Marshall Space Flight Center (MSFC) for use in-situ on the Moon-in particular for mineralogical analysis. The MSFC beam column design uses purely electrostatic fields for focusing, because of the severe constraints on mass and electrical power consumption imposed by the goals of lunar exploration and of spaceflight in general. The resolution of an SEM ultimately depends on the size of the focused spot of the scanning beam probe, for which the stated goal here is a diameter of 10 nanometers. Optical aberrations are the main challenge to this performance goal, because they blur the ideal geometrical optical image of the electron source, effectively widening the ideal spot size of the beam probe. In the present work the optical aberrations of the mini SEM focusing column were assessed using direct tracing of non-paraxial rays, as opposed to mathematical estimates of aberrations based on paraxial ray-traces. The geometrical ray-tracing employed here is completely analogous to ray-tracing as conventionally understood in the realm of photon optics, with the major difference being that in electron optics the lens is simply a smoothly varying electric field in vacuum, formed by precisely machined electrodes. Ray-tracing in this context, therefore, relies upon a model of the electrostatic field inside the focusing column to provide the mathematical description of the "lens" being traced. This work relied fundamentally on the boundary element method (BEM) for this electric field model. In carrying out this research the authors discovered that higher accuracy in the field model was essential if aberrations were to be reliably assessed using direct ray-tracing. This led to some work in testing alternative techniques for modeling the electrostatic field. Ultimately, the necessary accuracy was attained using a BEM

  13. Arguments as a new perspective on character motive in stories

    NARCIS (Netherlands)

    Bex, Floris; Atkinson, Katie; Bench-Capon, Trevor

    2014-01-01

    We often try to teach people through stories and narratives instead of giving them explicit facts and rules. But how do these stories influence us, how do they persuade us to change our attitudes? In this paper, we aim to answer these questions by providing a computational model that offers an inter

  14. Reading, Writing, and Mystery Stories.

    Science.gov (United States)

    Vardell, Sylvia M.

    1983-01-01

    Assesses students' responses to and production of story conventions in detective or mystery stories and explores students' responses to literature as potential connections between comprehending and composing text. (MM)

  15. Recension: Mao - The Unknown Story

    DEFF Research Database (Denmark)

    Clausen, Søren

    2005-01-01

    Anmeldelse - kritisk! - til Sveriges førende Kinatidsskrift af Jung Chang & Jon Halliday's sensationelle "Mao - the Unknown Story".......Anmeldelse - kritisk! - til Sveriges førende Kinatidsskrift af Jung Chang & Jon Halliday's sensationelle "Mao - the Unknown Story"....

  16. Pollyvocal: Short Stories

    OpenAIRE

    washington, gene

    2013-01-01

    Most fiction writers write (or attempt to write) in a univocal voice (or "style"). Hemingway's voice differs from Faulkner's, Carver's from Fitzgerald's and so on. Difference, it seems fair to say, helps to establish their identity. By contrast, this collection of stories embodies an attempt, over the last 55 years or so, to write in the polyvocal. One can see this "attempt" as an "interruption" of the old by the start of something "new." The voice of each story, with the exception of #1, int...

  17. Who reads love stories

    OpenAIRE

    Бочарова, Оксана

    1998-01-01

    Growth of the Russian book market is in the first place linked to reorientation of publishing to readers' interests and demand, and dissemination of mass and popular literature. The task of this paper is to define the place of love stories in the hierarchy of readers' interests, characterise their readers, and describe the location of these books in the mass culture space as well as the very motivation of taking up love stories. During seven or eight years in the Russian book market, this gen...

  18. A methodology to model causal relationships on offshore safety assessment focusing on human and organizational factors.

    Science.gov (United States)

    Ren, J; Jenkinson, I; Wang, J; Xu, D L; Yang, J B

    2008-01-01

    Focusing on people and organizations, this paper aims to contribute to offshore safety assessment by proposing a methodology to model causal relationships. The methodology is proposed in a general sense that it will be capable of accommodating modeling of multiple risk factors considered in offshore operations and will have the ability to deal with different types of data that may come from different resources. Reason's "Swiss cheese" model is used to form a generic offshore safety assessment framework, and Bayesian Network (BN) is tailored to fit into the framework to construct a causal relationship model. The proposed framework uses a five-level-structure model to address latent failures within the causal sequence of events. The five levels include Root causes level, Trigger events level, Incidents level, Accidents level, and Consequences level. To analyze and model a specified offshore installation safety, a BN model was established following the guideline of the proposed five-level framework. A range of events was specified, and the related prior and conditional probabilities regarding the BN model were assigned based on the inherent characteristics of each event. This paper shows that Reason's "Swiss cheese" model and BN can be jointly used in offshore safety assessment. On the one hand, the five-level conceptual model is enhanced by BNs that are capable of providing graphical demonstration of inter-relationships as well as calculating numerical values of occurrence likelihood for each failure event. Bayesian inference mechanism also makes it possible to monitor how a safety situation changes when information flow travel forwards and backwards within the networks. On the other hand, BN modeling relies heavily on experts' personal experiences and is therefore highly domain specific. "Swiss cheese" model is such a theoretic framework that it is based on solid behavioral theory and therefore can be used to provide industry with a roadmap for BN modeling and

  19. Focusing Azimuth-Invariant Bistatic Synthetic Aperture Radar Data Based on a Polynomial Model

    Institute of Scientific and Technical Information of China (English)

    ZHONG Hua; LIU Xing-zhao; WANG Jun-feng

    2009-01-01

    In this paper, a focusing approach is presented to widen the use of efficient monostatic imaging algorithms for azimuth-invariant bistatic synthetic aperture radar (SAR) data. The bistatic range history is modeled by a polynomial of azimuth time. Using this model, an analytic form of the signal spectrum in the 2D frequency domain is derived, and a simple single-valued relation between the transmitter and receive ranges is established. In this way, a lot of monostatic image formation algorithms can be extended for the bistatic SAR data, and a bistatic chirp scaling algorithm is developed as an application of the new approach. This algorithm can be used to process the azimuth-invariant bistatic configuration where the transmitter and receiver platforms are moving on parallel tracks with the same velocity. In addition, some simulation results are given to demonstrate the validity of the proposed approach.

  20. Sophie's story: writing missing journeys

    OpenAIRE

    Parr, Hester; Stevenson, Olivia

    2014-01-01

    'Sophie’s story' is a creative rendition of an interview narrative gathered in a research project on missing people. The paper explains why Sophie’s story was written and details the wider intention to provide new narrative resources for police officer training, families of missing people and returned missing people. We contextualize this cultural intervention with an argument about the transformative potential of writing trauma stories. It is suggested that trauma stories produce difficult a...

  1. Evaluation of soil-foundation-structure interaction effects on seismic response demands of multi-story MRF buildings on raft foundations

    Science.gov (United States)

    Abdel Raheem, Shehata E.; Ahmed, Mohamed M.; Alazrak, Tarek M. A.

    2015-03-01

    Soil conditions have a great deal to do with damage to structures during earthquakes. Hence the investigation on the energy transfer mechanism from soils to buildings during earthquakes is critical for the seismic design of multi-story buildings and for upgrading existing structures. Thus, the need for research into soil-structure interaction (SSI) problems is greater than ever. Moreover, recent studies show that the effects of SSI may be detrimental to the seismic response of structure and neglecting SSI in analysis may lead to un-conservative design. Despite this, the conventional design procedure usually involves assumption of fixity at the base of foundation neglecting the flexibility of the foundation, the compressibility of the underneath soil and, consequently, the effect of foundation settlement on further redistribution of bending moment and shear force demands. Hence the SSI analysis of multi-story buildings is the main focus of this research; the effects of SSI are analyzed for typical multi-story building resting on raft foundation. Three methods of analysis are used for seismic demands evaluation of the target moment-resistant frame buildings: equivalent static load; response spectrum methods and nonlinear time history analysis with suit of nine time history records. Three-dimensional FE model is constructed to investigate the effects of different soil conditions and number of stories on the vibration characteristics and seismic response demands of building structures. Numerical results obtained using SSI model with different soil conditions are compared to those corresponding to fixed-base support modeling assumption. The peak responses of story shear, story moment, story displacement, story drift, moments at beam ends, as well as force of inner columns are analyzed. The results of different analysis approaches are used to evaluate the advantages, limitations, and ease of application of each approach for seismic analysis.

  2. Disney stories getting to digital

    CERN Document Server

    Lee, Newton

    2012-01-01

    Highlights how technological innovation made Disney's characters and stories more engaging for audiences Explores how Disney uses contemporary gaming and online environments to create interactive stories Presents an insider's look at the creation process for their digital games, including The Lion King Animated Story Book, Disney Blast and Toontown

  3. Preschoolers' Quarantining of Fantasy Stories

    Science.gov (United States)

    Richert, Rebekah A.; Smith, Erin I.

    2011-01-01

    Preschool-aged children are exposed to fantasy stories with the expectation that they will learn messages in those stories that are applied to real-world situations. We examined children's transfer from fantastical and real stories. Over the course of 2 studies, 3 1/2- to 5 1/2-year-old children were less likely to transfer problem solutions from…

  4. Story Telling and Educational Understanding

    Science.gov (United States)

    Denny, Terry

    2011-01-01

    In this paper, the author first places story telling in context within the broad range of effort associated with case study methods. Then, the author discusses aspects of fieldwork which underlie story telling, first moves, key questions, tricks, listening, looking and synthesis. The author concludes with evaluative criteria for story telling and…

  5. Storytelling? Everyone Has a Story

    Science.gov (United States)

    Keller, Cynthia

    2012-01-01

    School librarians can assume an important role in preserving and perpetuating the oral tradition. The same skills and techniques when telling a personal story can be transmitted to telling various kinds of stories from literature and history. For school librarians to be successful storytellers, they need to select stories that they like and enjoy…

  6. Hmong story cloths

    National Research Council Canada - National Science Library

    Arkenberg, Rebecca

    2007-01-01

      The Hmong, a nomadic and agrarian people, may date back 5,000 years. Today there are about 150,000 Hmong in the United States, where their story cloths and embroidered items often appear in craft shows and exhibitions...

  7. Blue Willow Story Plates

    Science.gov (United States)

    Fontes, Kris

    2009-01-01

    In the December 1997 issue of "SchoolArts" is a lesson titled "Blue Willow Story Plates" by Susan Striker. In this article, the author shares how she used this lesson with her middle-school students many times over the years. Here, she describes a Blue Willow plate painting project that her students made.

  8. How Stories From Alaska.

    Science.gov (United States)

    Gray, Minnie

    Four simple "how" stories from Alaskan legend are presented in large type and amply illustrated. In "How the Caribou Lost His Teeth", Siqpik's only son is eaten by the sharp-toothed caribou, so Siqpik feeds the animal sour berries to make his teeth fall out. "How the Loon Got His Spots" relates how the raven paints…

  9. Gamers Telling Stories

    DEFF Research Database (Denmark)

    Albrechtslund, Anne-Mette Bech

    2010-01-01

    of Warcraft , make sense of their gaming experience, and how they build and uphold a community identity by telling stories online. I argue that in studying and conceptualizing these types of texts through the proposed theoretical framework, we can gain insights into the process of the formation of meaning...

  10. Putting Stories in Motion

    Science.gov (United States)

    Rhoades, Mindi

    2012-01-01

    A very successful preschool project the author did at Ohio State University's Schoenbaum Family Center combined students' interest in storytelling, drama, and multiple literacies. For this particular project, a classic children's fairy tale was used, though the project is easily adaptable for other stories, texts, content, and age levels. In this…

  11. Teaching Science through Story

    Science.gov (United States)

    Horton, Jessica

    2013-01-01

    Children find comfort in stories. They are familiar, accessible and entertaining. By teaching science through narratives, we can provide that same comfort and access to scientific content to children of all ages. In this article, I will discuss how, through the use of narratives in science instruction, we can provide students with a deeper…

  12. [Fictions and stories].

    Science.gov (United States)

    Martínez, H

    1995-12-01

    A short and interesting work, where the author of "The secret tooth", exposes some opinions about fiction and story, words he considers should not be opposed, but really on the contrary, be harmonized to contribute with their alliance for personal joy of readers. Writers like Joyce, Caillois, Updike, and others, are quoted for renewing texts with reports referred to Dentistry.

  13. Stories Under Your Feet

    DEFF Research Database (Denmark)

    Riesto, Svava; Støvring, Jan

    2014-01-01

    Review of the new Købmagergade design by Karres et Brandts and Polyform. The article discusses the new design, its uses and story-telling, seen in relation to the "urban space boom" in Copenhagen of the early 2000nds....

  14. New Suburban Stories

    NARCIS (Netherlands)

    Dines, M.; Vermeulen, T.J.V.

    2013-01-01

    Exploring fiction, film and art from across the USA, South America, Asia, Europe and Australia, New Suburban Stories brings together new research from leading international scholars to examine cultural representations of the suburbs, home to a rapidly increasing proportion of the world's population.

  15. Postcolonial Entanglements: Unruling Stories

    Science.gov (United States)

    Pacini-Ketchabaw, Veronica

    2012-01-01

    In this article, I use Donna Haraway's philosophy to think about postcolonial encounters between different species. I follow entangled stories of the deer/settler-child figure to trouble colonialisms and untangle the histories and trajectories that we inhabit with other species through colonial histories. I shy away from generalizations and…

  16. How's Your Story Arsenal?

    Science.gov (United States)

    Armstrong, Coleen

    1992-01-01

    Principals who wax eloquent over learning outcomes or socioeconomic factors are bound to bore their audiences. This article suggests ways to put zip into speeches and illustrate important points. Story and anecdotal material ranges from "the community leader who taught for a day" to "the worst child abuse case." All highlight people trying to…

  17. Teaching Ethics: Telling Stories.

    Science.gov (United States)

    Bowman, Ann

    1995-01-01

    In order to develop moral literacy, nursing students should be exposed to both rules- and justice-based ethics and to a feminist care perspective. They can learn to analyze and understand ethical dilemmas and to tell their own stories in order to identify the influences on their decision making. (SK)

  18. The Story of Iyal

    Centers for Disease Control (CDC) Podcasts

    2009-08-24

    In this podcast, a mother tells her compelling story about a family living with fetal alcohol spectrum disorders.  Created: 8/24/2009 by National Center on Birth Defects and Developmental Disabilities (NCBDDD).   Date Released: 8/24/2009.

  19. Modelling the temperature evolution of bone under high intensity focused ultrasound.

    Science.gov (United States)

    ten Eikelder, H M M; Bošnački, D; Elevelt, A; Donato, K; Di Tullio, A; Breuer, B J T; van Wijk, J H; van Dijk, E V M; Modena, D; Yeo, S Y; Grüll, H

    2016-02-21

    Magnetic resonance-guided high intensity focused ultrasound (MR-HIFU) has been clinically shown to be effective for palliative pain management in patients suffering from skeletal metastasis. The underlying mechanism is supposed to be periosteal denervation caused by ablative temperatures reached through ultrasound heating of the cortex. The challenge is exact temperature control during sonication as MR-based thermometry approaches for bone tissue are currently not available. Thus, in contrast to the MR-HIFU ablation of soft tissue, a thermometry feedback to the HIFU is lacking, and the treatment of bone metastasis is entirely based on temperature information acquired in the soft tissue adjacent to the bone surface. However, heating of the adjacent tissue depends on the exact sonication protocol and requires extensive modelling to estimate the actual temperature of the cortex. Here we develop a computational model to calculate the spatial temperature evolution in bone and the adjacent tissue during sonication. First, a ray-tracing technique is used to compute the heat production in each spatial point serving as a source term for the second part, where the actual temperature is calculated as a function of space and time by solving the Pennes bio-heat equation. Importantly, our model includes shear waves that arise at the bone interface as well as all geometrical considerations of transducer and bone geometry. The model was compared with a theoretical approach based on the far field approximation and an MR-HIFU experiment using a bone phantom. Furthermore, we investigated the contribution of shear waves to the heat production and resulting temperatures in bone. The temperature evolution predicted by our model was in accordance with the far field approximation and agreed well with the experimental data obtained in phantoms. Our model allows the simulation of the HIFU treatments of bone metastasis in patients and can be extended to a planning tool prior to MR

  20. Modelling the temperature evolution of bone under high intensity focused ultrasound

    Science.gov (United States)

    ten Eikelder, H. M. M.; Bošnački, D.; Elevelt, A.; Donato, K.; Di Tullio, A.; Breuer, B. J. T.; van Wijk, J. H.; van Dijk, E. V. M.; Modena, D.; Yeo, S. Y.; Grüll, H.

    2016-02-01

    Magnetic resonance-guided high intensity focused ultrasound (MR-HIFU) has been clinically shown to be effective for palliative pain management in patients suffering from skeletal metastasis. The underlying mechanism is supposed to be periosteal denervation caused by ablative temperatures reached through ultrasound heating of the cortex. The challenge is exact temperature control during sonication as MR-based thermometry approaches for bone tissue are currently not available. Thus, in contrast to the MR-HIFU ablation of soft tissue, a thermometry feedback to the HIFU is lacking, and the treatment of bone metastasis is entirely based on temperature information acquired in the soft tissue adjacent to the bone surface. However, heating of the adjacent tissue depends on the exact sonication protocol and requires extensive modelling to estimate the actual temperature of the cortex. Here we develop a computational model to calculate the spatial temperature evolution in bone and the adjacent tissue during sonication. First, a ray-tracing technique is used to compute the heat production in each spatial point serving as a source term for the second part, where the actual temperature is calculated as a function of space and time by solving the Pennes bio-heat equation. Importantly, our model includes shear waves that arise at the bone interface as well as all geometrical considerations of transducer and bone geometry. The model was compared with a theoretical approach based on the far field approximation and an MR-HIFU experiment using a bone phantom. Furthermore, we investigated the contribution of shear waves to the heat production and resulting temperatures in bone. The temperature evolution predicted by our model was in accordance with the far field approximation and agreed well with the experimental data obtained in phantoms. Our model allows the simulation of the HIFU treatments of bone metastasis in patients and can be extended to a planning tool prior to MR

  1. STORY WRITING AND ITS IMPORTANCE IN EFL TEACHING

    Institute of Scientific and Technical Information of China (English)

    YangQian

    2004-01-01

    The article explores the effectiveness of story writing in L2 teaching. A language teaching method based on the theory of language acquisition and focuses on students for active and meaningful learning is essential for EFL students. Free story writing, with its unique advantages, motivates and strengthens students' learning and improves students' writing ability by creating a strong context for the target language. The paper discusses the topic by examining the writing process, story principles, composition, and second language acquisition including Input Hypothesis and Affective Filter Hypothesis.

  2. Developing engineering model Cobra fiber positioners for the Subaru Telescope's prime focus spectrometer

    Science.gov (United States)

    Fisher, Charles; Morantz, Chaz; Braun, David; Seiffert, Michael; Aghazarian, Hrand; Partos, Eamon; King, Matthew; Hovland, Larry E.; Schwochert, Mark; Kaluzny, Joel; Capocasale, Christopher; Houck, Andrew; Gross, Johannes; Reiley, Daniel; Mao, Peter; Riddle, Reed; Bui, Khanh; Henderson, David; Haran, Todd; Culhane, Robert; Piazza, Daniele; Walkama, Eric

    2014-07-01

    The Cobra fiber positioner is being developed by the California Institute of Technology (CIT) and the Jet Propulsion Laboratory (JPL) for the Prime Focus Spectrograph (PFS) instrument that will be installed at the Subaru Telescope on Mauna Kea, Hawaii. PFS is a fiber fed multi-object spectrometer that uses an array of Cobra fiber positioners to rapidly reconfigure 2394 optical fibers at the prime focus of the Subaru Telescope that are capable of positioning a fiber to within 5μm of a specified target location. A single Cobra fiber positioner measures 7.7mm in diameter and is 115mm tall. The Cobra fiber positioner uses two piezo-electric rotary motors to move a fiber optic anywhere in a 9.5mm diameter patrol area. In preparation for full-scale production of 2550 Cobra positioners an Engineering Model (EM) version was developed, built and tested to validate the design, reduce manufacturing costs, and improve system reliability. The EM leveraged the previously developed prototype versions of the Cobra fiber positioner. The requirements, design, assembly techniques, development testing, design qualification and performance evaluation of EM Cobra fiber positioners are described here. Also discussed is the use of the EM build and test campaign to validate the plans for full-scale production of 2550 Cobra fiber positioners scheduled to begin in late-2014.

  3. Model of Thermal Wavefront Distortion in Interferometric Gravitational-Wave Detectors I Thermal Focusing

    CERN Document Server

    Beausoleil, R G; Kells, W; Camp, J; Gustafson, E K; Fejer, M M

    2002-01-01

    We develop a steady-state analytical and numerical model of the optical response of power-recycled Fabry-Perot Michelson laser gravitational-wave detectors to thermal focusing in optical substrates. We assume that the thermal distortions are small enough that we can represent the unperturbed intracavity field anywhere in the detector as a linear combination of basis functions related to the eigenmodes of one of the Fabry-Perot arm cavities, and we take great care to preserve numerically the nearly ideal longitudinal phase resonance conditions that would otherwise be provided by an external servo-locking control system. We have included the effects of nonlinear thermal focusing due to power absorption in both the substrates and coatings of the mirrors and beamsplitter, the effects of a finite mismatch between the curvatures of the laser wavefront and the mirror surface, and the diffraction by the mirror aperture at each instance of reflection and transmission. We demonstrate a detailed numerical example of thi...

  4. Developing Engineering Model Cobra fiber positioners for the Subaru Telescope Prime Focus Spectrometer

    CERN Document Server

    Fisher, Charles; Braun, David; Seiffert, Michael; Aghazarian, Hrand; Partos, Eamon; King, Matthew; Hovland, Larry; Schwochert, Mark; Kaluzny, Joel; Capocasale, Christopher; Houck, Andrew; Gross, Johannes; Reiley, Dan; Mao, Peter; Riddle, Reed; Bui, Khanh; Henderson, David; Haran, Todd; Culhane, Rob; Piazza, Daniele; Walkama, Eric

    2014-01-01

    The Cobra fiber positioner is being developed by the California Institute of Technology (CIT) and the Jet Propulsion Laboratory (JPL) for the Prime Focus Spectrograph (PFS) instrument that will be installed at the Subaru Telescope on Mauna Kea, Hawaii. PFS is a fiber fed multi-object spectrometer that uses an array of Cobra fiber positioners to rapidly reconfigure 2394 optical fibers at the prime focus of the Subaru Telescope that are capable of positioning a fiber to within 5um of a specified target location. A single Cobra fiber positioner measures 7.7mm in diameter and is 115mm tall. The Cobra fiber positioner uses two piezo-electric rotary motors to move a fiber optic anywhere in a 9.5mm diameter patrol area. In preparation for full-scale production of 2550 Cobra positioners an Engineering Model (EM) version was developed, built and tested to validate the design, reduce manufacturing costs, and improve system reliability. The EM leveraged the previously developed prototype versions of the Cobra fiber posi...

  5. In vitro psoriasis models with focus on reconstructed skin models as promising tools in psoriasis research.

    Science.gov (United States)

    Desmet, Eline; Ramadhas, Anesh; Lambert, Jo; Van Gele, Mireille

    2017-06-01

    skin or the disease pathology. This work provides a complete overview of the different available in vitro psoriasis models and suggests improvements for future models. Moreover, a focus was given to psoriatic skin equivalent models, as they offer several advantages over the other models, including commercial availability and validity. The potential and reported applicability of these models in psoriasis pre-clinical research is extensively discussed. As such, this work offers a guide to researchers in their choice of pre-clinical psoriasis model depending on their type of research question.

  6. Numerical focusing methods for full field OCT: a comparison based on a common signal model.

    Science.gov (United States)

    Kumar, Abhishek; Drexler, Wolfgang; Leitgeb, Rainer A

    2014-06-30

    In this paper a theoretical model of the full field swept source (FF SS) OCT signal is presented based on the angular spectrum wave propagation approach which accounts for the defocus error with imaging depth. It is shown that using the same theoretical model of the signal, numerical defocus correction methods based on a simple forward model (FM) and inverse scattering (IS), the latter being similar to interferometric synthetic aperture microscopy (ISAM), can be derived. Both FM and IS are compared quantitatively with sub-aperture based digital adaptive optics (DAO). FM has the least numerical complexity, and is the fastest in terms of computational speed among the three. SNR improvement of more than 10 dB is shown for all the three methods over a sample depth of 1.5 mm. For a sample with non-uniform refractive index with depth, FM and IS both improved the depth of focus (DOF) by a factor of 7x for an imaging NA of 0.1. DAO performs the best in case of non-uniform refractive index with respect to DOF improvement by 11x.

  7. Flow Visualization around a Double Wedge Airfoil Model with Focusing Schlieren System

    Institute of Scientific and Technical Information of China (English)

    Masashi KASHITANI; Yutaka YAMAGUCHI

    2006-01-01

    In the present study, aerodynamic characteristics of the double wedge airfoil model were investigated in a transonic flow by using the shock tube as an intermittent wind tunnel. The driver and driven gases of the shock tube are dry air. The airfoil model of double wedge has the span of 58 mm, chord length c = 75 mm and its maximum thickness is 7.5 mm. The apex of the double wedge airfoil model is located on the 35% chord length from the leading edge. The range of hot gas Mach numbers are from 0.80 to 0.88, and the Reynolds numbers based on chord length are 3.11×105~3.49×105, respectively. The flow visualizations were performed by the sharp focusing schlieren method which can visualize the three dimensional flow fields. The results show that the present system can visualize the transonic flowfield clearer than the previous system, and the shock wave profiles of the center of span in the test section are visualized

  8. Motivational cues predict the defensive system in team handball: A model based on regulatory focus theory.

    Science.gov (United States)

    Debanne, T; Laffaye, G

    2015-08-01

    This study was based on the naturalistic decision-making paradigm and regulatory focus theory. Its aim was to model coaches' decision-making processes for handball teams' defensive systems based on relevant cues of the reward structure, and to determine the weight of each of these cues. We collected raw data by video-recording 41 games that were selected using a simple random method. We considered the defensive strategy (DEF: aligned or staged) to be the dependent variable, and the three independent variables were (a) numerical difference between the teams; (b) score difference between the teams; and (c) game periods. We used a logistic regression design (logit model) and a multivariate logistic model to explain the link between DEF and the three category independent variables. Each factor was weighted differently during the decision-making process to select the defensive system, and combining these variables increased the impact on this process; for instance, a staged defense is 43 times more likely to be chosen during the final period in an unfavorable situation and in a man advantage. Finally, this shows that the coach's decision-making process could be based on a simple match or could require a diagnosis of the situation based on the relevant cues.

  9. Role modelling of clinical tutors: a focus group study among medical students.

    Science.gov (United States)

    Burgess, Annette; Goulston, Kerry; Oates, Kim

    2015-02-14

    Role modelling by clinicians assists in development of medical students' professional competencies, values and attitudes. Three core characteristics of a positive role model include 1) clinical attributes, 2) teaching skills, and 3) personal qualities. This study was designed to explore medical students' perceptions of their bedside clinical tutors as role models during the first year of a medical program. The study was conducted with one cohort (n = 301) of students who had completed Year 1 of the Sydney Medical Program in 2013. A total of nine focus groups (n = 59) were conducted with medical students following completion of Year 1. Data were transcribed verbatim. Thematic analysis was used to code and categorise data into themes. Students identified both positive and negative characteristics and behaviour displayed by their clinical tutors. Characteristics and behaviour that students would like to emulate as medical practitioners in the future included: 1) Clinical attributes: a good knowledge base; articulate history taking skills; the ability to explain and demonstrate skills at the appropriate level for students; and empathy, respect and genuine compassion for patients. 2) Teaching skills: development of a rapport with students; provision of time towards the growth of students academically and professionally; provision of a positive learning environment; an understanding of the student curriculum and assessment requirements; immediate and useful feedback; and provision of patient interaction. 3) Personal qualities: respectful interprofessional staff interactions; preparedness for tutorials; demonstration of a passion for teaching; and demonstration of a passion for their career choice. Excellence in role modelling entails demonstration of excellent clinical care, teaching skills and personal characteristics. Our findings reinforce the important function of clinical bedside tutors as role models, which has implications for faculty development and

  10. JPEG color barcode images analysis: A camera phone capture channel model with auto-focus

    Directory of Open Access Journals (Sweden)

    Keng T. Tan

    2009-12-01

    Full Text Available As camera phones have permeated into our everyday lives, two dimensional (2D barcode has attracted researchers and developers as a cost-effective ubiquitous computing tool. A variety of 2D barcodes and their applications have been developed. Often, only monochrome2D barcodes are used due to their robustness in an uncontrolled operating environment of camera phones. However, we are seeing an emerging use of color 2D barcodes for camera phones. Nonetheless, using a greater multitude of colors introduces errors that can negatively affect the robustness of barcode reading. This is especially true when developing a 2D barcode for camera phones which capture and store these barcode images in the baselineJPEG format. This paper presents one aspect of the errors introduced by such camera phones by modeling the camera phone capture channel for JPEG color barcode images wherein there is camera auto-focus.

  11. Introduction to Focus Issue: Rhythms and Dynamic Transitions in Neurological Disease: Modeling, Computation, and Experiment

    Energy Technology Data Exchange (ETDEWEB)

    Kaper, Tasso J., E-mail: tasso@bu.edu; Kramer, Mark A., E-mail: mak@bu.edu [Department of Mathematics and Statistics, Boston University, Boston, Massachusetts 02215 (United States); Rotstein, Horacio G., E-mail: horacio@njit.edu [Department of Mathematical Sciences, New Jersey Institute of Technology, Newark, New Jersey 07102 (United States)

    2013-12-15

    Rhythmic neuronal oscillations across a broad range of frequencies, as well as spatiotemporal phenomena, such as waves and bumps, have been observed in various areas of the brain and proposed as critical to brain function. While there is a long and distinguished history of studying rhythms in nerve cells and neuronal networks in healthy organisms, the association and analysis of rhythms to diseases are more recent developments. Indeed, it is now thought that certain aspects of diseases of the nervous system, such as epilepsy, schizophrenia, Parkinson's, and sleep disorders, are associated with transitions or disruptions of neurological rhythms. This focus issue brings together articles presenting modeling, computational, analytical, and experimental perspectives about rhythms and dynamic transitions between them that are associated to various diseases.

  12. Laser-enhanced high-intensity focused ultrasound heating in an in vivo small animal model

    Science.gov (United States)

    Jo, Janggun; Yang, Xinmai

    2016-11-01

    The enhanced heating effect during the combination of high-intensity focused ultrasound (HIFU) and low-optical-fluence laser illumination was investigated by using an in vivo murine animal model. The thighs of murine animals were synergistically irradiated by HIFU and pulsed nano-second laser light. The temperature increases in the target region were measured by a thermocouple under different HIFU pressures, which were 6.2, 7.9, and 9.8 MPa, in combination with 20 mJ/cm2 laser exposures at 532 nm wavelength. In comparison with conventional laser therapies, the laser fluence used here is at least one order of magnitude lower. The results showed that laser illumination could enhance temperature during HIFU applications. Additionally, cavitation activity was enhanced when laser and HIFU irradiation were concurrently used. Further, a theoretical simulation showed that the inertial cavitation threshold was indeed decreased when laser and HIFU irradiation were utilized concurrently.

  13. Introduction to Focus Issue: Rhythms and Dynamic Transitions in Neurological Disease: Modeling, Computation, and Experiment

    Science.gov (United States)

    Kaper, Tasso J.; Kramer, Mark A.; Rotstein, Horacio G.

    2013-12-01

    Rhythmic neuronal oscillations across a broad range of frequencies, as well as spatiotemporal phenomena, such as waves and bumps, have been observed in various areas of the brain and proposed as critical to brain function. While there is a long and distinguished history of studying rhythms in nerve cells and neuronal networks in healthy organisms, the association and analysis of rhythms to diseases are more recent developments. Indeed, it is now thought that certain aspects of diseases of the nervous system, such as epilepsy, schizophrenia, Parkinson's, and sleep disorders, are associated with transitions or disruptions of neurological rhythms. This focus issue brings together articles presenting modeling, computational, analytical, and experimental perspectives about rhythms and dynamic transitions between them that are associated to various diseases.

  14. CASE STUDY ON THE IMPLEMENTATION OF A VIDEO STORY-BASED INTERVENTI­ON WITH SELF-MODELING TREATMENT PACKAGE TO REDUCE STEREOTYPICAL SPITTING BEHAVIOR IN A YOUNG GIRL WITH AUTISM

    Directory of Open Access Journals (Sweden)

    Cindy NELSON-HEAD

    2012-09-01

    Full Text Available The purpose of this study was to investigate the use of a video story-based intervention with self-modeling to decrease spitting behavior in a female pre-school student with autism during an extended school year ser­vices program. An A-B-A-B design was used to demonstrate a functional relation between a video story-based intervention with self-modeling and decreased spitting be­havior. The results showed that spitting behavior de­crea­sed as a result of the video-based in­ter­vention package. The implications of these re­sults will be explored.

  15. Generation of Variations on Theme Music Based on Impressions of Story Scenes Considering Human's Feeling of Music and Stories

    Directory of Open Access Journals (Sweden)

    Kenkichi Ishizuka

    2008-01-01

    Full Text Available This paper describes a system which generates variations on theme music fitting to story scenes represented by texts and/or pictures. Inputs to the present system are original theme music and numerical information on given story scenes. The present system varies melodies, tempos, tones, tonalities, and accompaniments of given theme music based on impressions of story scenes. Genetic algorithms (GAs using modular neural network (MNN models as fitness functions are applied to music generation in order to reflect user's feeling of music and stories. The present system adjusts MNN models for each user on line. This paper also describes the evaluation experiments to confirm whether the generated variations on theme music reflect impressions of story scenes appropriately or not.

  16. "We Decided to Call It Quits": An Exercise in Applying Duck's Dissolution Model to Students' Breakup Stories

    Science.gov (United States)

    Barton, Matthew H.; Turman, Paul D.

    2008-01-01

    Steve Duck's scholarship has made a noticeable impact on the study of interpersonal communication. Of his works, one of the most noteworthy is the explanatory model of relationship disengagement and dissolution. Duck's Dissolution Model (DDM) explains the stages that relationships pass through when they encounter stress resulting in two…

  17. Liver as a focus of impaired oxygenation and cytokine production in a porcine model of endotoxicosis.

    Science.gov (United States)

    Bathe, O F; Rudston-Brown, B; Chow, A W; Phang, P T

    1998-10-01

    To determine whether the liver is a focus of insufficient oxygenation and whether liver is a source of tumor necrosis factor (TNF) and interleukin-6 (IL-6) in a porcine model of endotoxicosis. In vivo, prospective, controlled, repeated-measures, experimental study. Experimental physiology laboratory in a university. Juvenile pigs, weighing 22 to 35 kg. Catheters for blood sampling were inserted into the carotid artery, portal vein, hepatic vein, and pulmonary artery of anesthetized animals. Ultrasonic flow probes were placed on the portal vein and the hepatic artery. During surgery, normal saline was infused intravenously at 25 mL/kg/hr. Following stabilization, animals were allocated randomly to one of two groups. The endotoxemic group (n = 6) received 50 mg/kg of purified Escherichia coli lipopolysaccharide infused into the external jugular vein over 1 hr. The control group (n = 6) received a sham saline infusion infused over 1 hr. Once the endotoxin or sham infusion was initiated, the rate of the intravenous saline infusion was increased to 48 mL/kg/hr for the remainder of the experiment. Measurements were obtained before the endotoxin or sham infusion, immediately after the infusion, and every 30 mins thereafter for 4 hrs. Blood gases, lactate, and bioactive TNF and IL-6 concentrations were measured from the carotid artery, portal vein, hepatic vein, and pulmonary artery. The porcine model is characterized by systemic hypotension, pulmonary hypertension, and maintenance of cardiac output. Despite decreased hepatic oxygen delivery in endotoxemic animals (p oxygen consumption compared with controls. Throughout the experiment, there was net hepatic consumption of lactate in both groups. There was no significant hepatic production (or consumption) of TNF or IL-6 in either group. In this porcine model of endotoxicosis, there is a reduction of hepatic oxygen delivery but dysoxia is not present. The liver is not a source of TNF or IL-6 in this model of endotoxicosis.

  18. Modeling and Predicting Tissue Movement and Deformation for High Intensity Focused Ultrasound Therapy

    Science.gov (United States)

    Liao, Xiangyun; Yuan, Zhiyong; Lai, Qianfeng; Guo, Jiaxiang; Zheng, Qi; Yu, Sijiao; Tong, Qianqian; Si, Weixin; Sun, Mingui

    2015-01-01

    Purpose In ultrasound-guided High Intensity Focused Ultrasound (HIFU) therapy, the target tissue (such as a tumor) often moves and/or deforms in response to an external force. This problem creates difficulties in treating patients and can lead to the destruction of normal tissue. In order to solve this problem, we present a novel method to model and predict the movement and deformation of the target tissue during ultrasound-guided HIFU therapy. Methods Our method computationally predicts the position of the target tissue under external force. This prediction allows appropriate adjustments in the focal region during the application of HIFU so that the treatment head is kept aligned with the diseased tissue through the course of therapy. To accomplish this goal, we utilize the cow tissue as the experimental target tissue to collect spatial sequences of ultrasound images using the HIFU equipment. A Geodesic Localized Chan-Vese (GLCV) model is developed to segment the target tissue images. A 3D target tissue model is built based on the segmented results. A versatile particle framework is constructed based on Smoothed Particle Hydrodynamics (SPH) to model the movement and deformation of the target tissue. Further, an iterative parameter estimation algorithm is utilized to determine the essential parameters of the versatile particle framework. Finally, the versatile particle framework with the determined parameters is used to estimate the movement and deformation of the target tissue. Results To validate our method, we compare the predicted contours with the ground truth contours. We found that the lowest, highest and average Dice Similarity Coefficient (DSC) values between predicted and ground truth contours were, respectively, 0.9615, 0.9770 and 0.9697. Conclusion Our experimental result indicates that the proposed method can effectively predict the dynamic contours of the moving and deforming tissue during ultrasound-guided HIFU therapy. PMID:25993644

  19. Modeling of high-intensity focused ultrasound-induced lesions in the presence of cavitation bubbles

    Science.gov (United States)

    Chavrier; Chapelon; Gelet; Cathignol

    2000-07-01

    The classical "Bio Heat Transfer Equation (BHTE)" model is adapted to take into account the effects of oscillating microbubbles that occur naturally in the tissue during high-intensity focused ultrasound (HIFU) treatment. First, the Gilmore-Akulichev model is used to quantify the acoustic pressure scattered by microbubbles submitted to HIFU. Because this scattered pressure is not monochromatic, the concept of harmonic attenuation is introduced and a global attenuation coefficient is estimated for bubble-filled tissues. The first results show that this global attenuation coefficient varies significantly with respect to several parameters such as the frequency and the density of microbubbles in the medium, but also with respect to the incident acoustic pressure which thus becomes a transcendental function. Under these conditions, a layer-by-layer modeling, in the direction of propagation, is proposed to calculate the ultrasonic beam. Finally, the BHTE is solved and the HIFU-induced lesions are estimated by the calculation of the thermal dose. Using this model, it can be observed first that, when the firing power increases, the lesion develops clearly in the direction of the transducer, with a shape agreeing with in vivo experimentation. Next, it is observed that the lesion can be significantly modified in size and position, if an interface (skin or inner wall) is simulated as a zone with multiple cavitation nuclei. With a firing power increase, it is also shown how a secondary lesion can appear at the interface and how, beyond a certain threshold, this lesion develops at the main lesion expense. Finally, a better in-depth homogeneity of lesions is observed when the acoustic frequency of HIFU is increased.

  20. Particle-in-cell modeling for MJ scale dense plasma focus with varied anode shape

    Energy Technology Data Exchange (ETDEWEB)

    Link, A., E-mail: link6@llnl.gov; Halvorson, C., E-mail: link6@llnl.gov; Schmidt, A. [Lawrence Livermore National Laboratory, Livermore, CA 94550 (United States); Hagen, E. C. [National Security Technologies, Las Vegas, NV 89030 (United States); Rose, D. V.; Welch, D. R. [Voss Scientific LLC, Albuquerque NM 87108 (United States)

    2014-12-15

    Megajoule scale dense plasma focus (DPF) Z-pinches with deuterium gas fill are compact devices capable of producing 10{sup 12} neutrons per shot but past predictive models of large-scale DPF have not included kinetic effects such as ion beam formation or anomalous resistivity. We report on progress of developing a predictive DPF model by extending our 2D axisymmetric collisional kinetic particle-in-cell (PIC) simulations from the 4 kJ, 200 kA LLNL DPF to 1 MJ, 2 MA Gemini DPF using the PIC code LSP. These new simulations incorporate electrodes, an external pulsed-power driver circuit, and model the plasma from insulator lift-off through the pinch phase. To accommodate the vast range of relevant spatial and temporal scales involved in the Gemini DPF within the available computational resources, the simulations were performed using a new hybrid fluid-to-kinetic model. This new approach allows single simulations to begin in an electron/ion fluid mode from insulator lift-off through the 5-6 μs run-down of the 50+ cm anode, then transition to a fully kinetic PIC description during the run-in phase, when the current sheath is 2-3 mm from the central axis of the anode. Simulations are advanced through the final pinch phase using an adaptive variable time-step to capture the fs and sub-mm scales of the kinetic instabilities involved in the ion beam formation and neutron production. Validation assessments are being performed using a variety of different anode shapes, comparing against experimental measurements of neutron yield, neutron anisotropy and ion beam production.

  1. Focused ultrasound facilitated thermo-chemotherapy for targeted retinoblastoma treatment: a modeling study.

    Science.gov (United States)

    Wang, Shutao; Mahesh, Sankaranarayana P; Liu, Ji; Geist, Craig; Zderic, Vesna

    2012-07-01

    Retinoblastoma is the most common type of intraocular tumors in children. Currently, with early detection and improved systemic chemo-adjuvant therapies, treatment paradigm has shifted from survival to globe salvation/vision preservation. The objective of our work has been to explore the possible application of focused ultrasound (FUS) for targeted drug delivery in the posterior pole retinoblastoma. Specifically, theoretical models were implemented to evaluate the feasibility of using FUS to generate localized hyperthermia in retinal tumor areas, for potential triggering the chemotherapeutic agent deployment from heat-sensitive drug carriers. In-vitro experiments were conducted in tissue-mimicking phantoms with embedded excised rabbit eyes to validate the reliability of the modeling results. After confirming the reliability of our model, various FUS transducer parameters were investigated to induce maximal hyperthermia coverage in the tumor, while sparing adjacent eye structures (e.g. the lens). The evaluated FUS parameters included operating frequency, total acoustic power, geometric dimensions, transducer f-number, standoff distance, as well as different pulsing scenarios. Our modeling results suggest that the most suitable ultrasound frequency for this type of treatments was in the range of 2-3.5 MHz depending on the size of retinoblastoma. Appropriate transducer f-number (close to 1) and standoff distance could be selected to minimize the risks of over-heating undesired regions. With the total acoustic power of 0.4 W, 56.3% of the tumor was heated to hyperthermic temperature range (39-44 °C) while the temperature in lens was maintained below 41 °C. In conclusion, FUS-induced hyperthermia for targeted drug delivery may be a viable option in treatments of juxta-foveal or posterior pole retinoblastomas. Future in-vivo studies will allow us to determine the effectiveness and safety of the proposed approach. Copyright © 2012 Elsevier Ltd. All rights reserved.

  2. Mechanistic PBPK Modeling of the Dissolution and Food Effect of a BCS IV Compound - the Venetoclax Story.

    Science.gov (United States)

    Emami Riedmaier, Arian; Lindley, David J; Hall, Jeffrey A; Castleberry, Steven; Slade, Russell T; Stuart, Patricia; Carr, Robert A; Borchardt, Thomas B; Bow, Daniel A J; Nijsen, Marjoleen

    2017-10-06

    Venetoclax, a selective B-cell lymphoma-2 inhibitor, is a biopharmaceutics classification system (BCS) class IV compound. The aim of this study was to develop a physiologically-based pharmacokinetic (PBPK) model to mechanistically describe absorption and disposition of an amorphous solid dispersion (ASD) formulation of venetoclax in humans. A mechanistic PBPK model was developed incorporating measured amorphous solubility, dissolution, metabolism and plasma protein binding. A middle-out approach was used to define permeability. Model predictions of oral venetoclax pharmacokinetics were verified against clinical studies of fed and fasted healthy volunteers, and clinical drug interaction studies with strong CYP3A inhibitor (ketoconazole) and inducer (rifampicin). Model verification demonstrated accurate prediction of the observed food effect following a low-fat diet. Ratios of predicted versus observed Cmax and AUC of venetoclax were within 0.8- to 1.25-fold of observed ratios for strong CYP3A inhibitor and inducer interactions, indicating that the venetoclax elimination pathway was correctly specified. The verified venetoclax PBPK model is one of the first examples mechanistically capturing absorption, food effect and exposure of an ASD formulated compound. This model allows evaluation of untested drug-drug interactions, especially those primarily occurring in the intestine, and paves the way for future modeling of BCS IV compounds. Copyright © 2017. Published by Elsevier Inc.

  3. Modeling of Focused Acoustic Field of a Concave Multi-annular Phased Array Using Spheroidal Beam Equation

    Institute of Scientific and Technical Information of China (English)

    余立立; 寿文德; 惠春

    2012-01-01

    A theoretical model of focused acoustic field for a multi-annular phased array on concave spherical surface is proposed. In this model, the source boundary conditions of the spheroidal beam equation (SBE) for multi-annular phased elements are studied. Acoustic field calculated by the dynamic focusing model of SBE is compared with numerical results of the O'Neil and Khokhlov-Zabolotskaya-Kuznetsov (KZK) model, respectively. Axia/dynamic focusing and the harmonic effects are presented. The results demonstrate that the dynamic focusing model of SBE is good valid for a concave multi-annular phased array with a large aperture angle in the linear or nonlinear field.

  4. Focusing Modeling of OPFC Linear Array Transducer by Using Distributed Point Source Method

    Directory of Open Access Journals (Sweden)

    Ziping Wang

    2014-01-01

    Full Text Available The improvement of ultrasonic phased array detection technology is a major concern of engineering community. Orthotropic piezoelectric fiber composite (OPFC can be constructed to multielement linear array which may be applied conveniently to actuators and sensors. The phased array transducers can generate special directional strong actuator power and high sensitivity for its orthotropic performance. Focusing beam of the linear phased array transducer is obtained simply only by adjusting a parabolic time delay. In this work, the distributed point source method (DPSM is used to model the ultrasonic field. DPSM is a newly developed mesh-free numerical technique that has been developed for solving a variety of engineering problems. This work gives the basic theory of this method and solves the problems from the application of new OPFC phased array transducer. Compared with traditional transducer, the interaction effect of two OPFC linear phased array transducers is also modeled in the same medium, which shows that the pressure beam produced by the new transducer is narrower or more collimated than that produced by the conventional transducer at different angles. DPSM can be used to analyze and optimally design the OPFC linear phased array transducer.

  5. Stories, Heroes and Commercials. Spreading the Message across with a New Type of Responsibility

    Directory of Open Access Journals (Sweden)

    Ana ADI

    2015-12-01

    Full Text Available Stories have always been a form of communication, the first form of narrative we have encountered in early childhood. And although we have grown up they continue to fascinate us. They maintain and recreate bonds with old traditions, legends, archetypes, myths and symbols. In analyzing stories, Joseph Campbell (2008 proposed the monomyth or the Hero's Journey, a basic pattern, which comprises fundamental stages and structures identifiable in all narratives from different cultures and ages. Although the pattern was further refined and enriched according to the specifics of the narrative (myth, fairy tale, dream, movie etc. the common structural elements of the Hero's Journey from the ordinary world to a challenging and unfamiliar world include: the departure, the initiation and the return. Picking up on Campbell’s model, Sachs (2012 proposes a circular representation of the hero and his/her journey. In this model, a new character, the mentor, plays a pivotal role in the shaping of the hero and his/her transformation. It is the mentor that supports the hero in her/his taking the call to adventure as well as in providing the needed support for crossing the thresholds to the supernatural world and back. Based on what Sachs (2012 suggests that brands could use storytelling as a means to engage with consumers. In doing so he argues that brands should reflect and adopt the role of mentors in their consumers’ journeys, guiding them through the challenges on their own world and contributing to their personal fulfillment. This paper aims to evaluate four stories, all focused on women and empowerment and as a result our discussion focuses mainly on the position of the brand within the story and its role. This, we believe, may contribute to a new trend focused on the adoption and applications of empowerment storytelling.

  6. Translational value of animal models of obesity-Focus on dogs and cats.

    Science.gov (United States)

    Osto, Melania; Lutz, Thomas A

    2015-07-15

    A prolonged imbalance between a relative increase in energy intake over a decrease in energy expenditure results in the development of obesity; extended periods of a positive energy balance eventually lead to the accumulation of abnormally high amounts of fat in adipose tissue but also in other organs. Obesity is considered a clinical state of impaired general heath in which the excessive increase in adipose tissue mass may be associated with metabolic disorders such as type 2 diabetes mellitus, hyperlipidemia, hypertension and cardiovascular diseases. This review discusses briefly the use of animal models for the study of obesity and its comorbidities. Generally, most studies are performed with rodents, such as diet induced obesity and genetic models. Here, we focus specifically on two different species, namely dogs and cats. Obese dogs and cats show many features of human obesity. Interestingly, however, dogs and cats differ from each other in certain aspects because even though obese dogs may become insulin resistant, this does not result in the development of diabetes mellitus. In fact, diabetes in dogs is typically not associated with obesity because dogs present a type 1 diabetes-like syndrome. On the other hand, obese cats often develop diabetes mellitus which shares many features with human type 2 diabetes; feline and human diabetes are similar in respect to their pathophysiology, underlying risk factors and treatment strategies. Our review discusses genetic and endocrine factors in obesity, discusses obesity induced changes in lipid metabolism and includes some recent findings on the role of gut microbiota in obesity. Compared to research in rodent models, the array of available techniques and tools is unfortunately still rather limited in dogs and cats. Hence, even though physiological and pathophysiological phenomena are well described in dogs and cats, the underlying mechanisms are often not known and studies investigating causality specifically are

  7. The Varian story

    Science.gov (United States)

    Freeman, Ray; Morris, Gareth A.

    2015-01-01

    This Perspective offers a personal view of the story of Varian NMR, a courageous initiative that began in the 1950s but came to an abrupt end some 60 years later. Without doubt, Varian leaves behind a priceless legacy, particularly in the field of structural chemistry. The highlights are set out in four main sections, named after the four seasons, but not necessarily in strict chronology. How did the accepted business practices influence the evolution, growth, and eventual demise of this exciting venture? How well did management handle an unconventional group of young scientific entrepreneurs? What does it all mean for the future of magnetic resonance? The subject can be viewed on two different levels, the Varian story itself, and the larger picture - the Silicon Valley phenomenon as a whole, with Varian considered as an interesting microcosm.

  8. Teddy Bear Stories

    DEFF Research Database (Denmark)

    van Leeuwen, Theo; Caldas-Coulthardt, Carmen

    2014-01-01

    This paper presents a semiotic analysis of a key cultural artefact, the teddy bear. After introducing the iconography of the teddy bear, it analyses different kinds of stories to show how teddy bears are endowed with meaning in everyday life: stories from children's books, reminiscenses by adults...... about their childhood teddy bears, and children's accounts of what they do with teddy bears, both written for school and told 'out of school', The chapter sees teddy bears as artefacts that provide a cultural channeling for the child's need of a transitional object and argues that the meanings of teddy...... bears have traditionally centred on interpersonal relations within the nuclear family, but have recently been institutionalized and commercialized....

  9. An Airmans Story

    Science.gov (United States)

    2016-08-01

    would have worldwide civil implications as well. Civil aviation, Wall Street and the agricultural community are just a sample of orga- nizations...questionable. Not coincidently, civil aircraft, Wall Street and the agriculture community face the same dire impacts if civil cyberspace is unavailable as well...4 | Air & Space Power Journal An Airman’s Story General John E. Hyten, USAF Disclaimer: The views and opinions expressed or implied in the Journal

  10. Investigating media stories

    Science.gov (United States)

    Lowe, Stuart

    2008-08-01

    Perceived lapses of fact or emphasis in popular science coverage in the media can irritate active researchers: concern for establishing facts and details of scientific arguments can override appreciation of the value of a good popular story in the press. A programme to educate early-career astronomers about the different goals and priorities of the wider media is equipping research stars of the future to get their messages across.

  11. Storie di genere, storie di partito

    Directory of Open Access Journals (Sweden)

    Elisa Bellè

    2012-04-01

    Full Text Available Lo studio delle narrazioni di genere all'interno di questo tipo di organizzazione desta inoltre un particolare interesse anche in ragione della sottorappresentazione delle donne nella sfera della politica. Si tratta di un deficit democratico che coinvolge i sistemi politici moderni nel loro complesso, ma che interessa l'Italia con una particolare gravità ed evidenza. La questione della sottorappresentazione politica delle donne è stata sinora affrontata prevalentemente in termini tecnico-legali (politiche di pari opportunità ed azione positiva, o di teoria politica (la dicotomia pubblico-maschile e privato-femminile come fondamento del contratto sessuale della politica. Mancano invece contributi che guardino ai partiti come organizzazioni largamente responsabili dei processi di selezione e promozione delle carriere politiche, dunque come luoghi di quotidiana produzione di pratiche e culture di genere, più o meno egualitarie o, viceversa, discriminatorie. Sulla base di tale vuoto di ricerca e riflessione, il presente articolo si propone di mettere in luce le pratiche e le culture di genere che emergono dai racconti di uomini e donne all'interno di due organizzazioni partitiche, una di destra e una di sinistra, situate nel contesto territoriale della provincia di Trento. La ricerca è stata condotta attraverso lo strumento dell'intervista semi-strutturata, coinvolgendo quattro donne e quattro uomini, divisi per coppie di età (un uomo ed una donna giovani ed un uomo ed una donna da lungo presenti nel partito, accostabili per quanto concerne ruolo e posizione nelle organizzazioni partitiche considerate. L'attenzione analitica si è concentrata sulla costruzione del genere di uomini e donne intervistati/e, intesa sia come dimensione ed esperienza individuale (le storie di genere dei/lle singoli/e, sia come dimensione organizzativa più ampia (le storie di genere delle organizzazioni, narrate dalle diverse voci. Un'ulteriore dimensione analitica

  12. Evaluating neurology CME in two educational methods using Patton's utilization focused model.

    Science.gov (United States)

    Vakani, Farhan; Ahmad, Amina; Sonawalla, Aziz; Sheerani, Mughis

    2013-01-01

    Generally in continuing education medical education (CME) the most time is consumed for in the planning and preparation of the event. This planning and preparation, however, needs recognition through an evaluative process. The purpose of this study was to evaluate neurology CME in two educational methods, lecture vs task-based learning, using Patton's utilisation focused model. This was an observational, cross-sectional inquiry. The questionnaire evaluated the educational elements such as learning objectives met, content covered, presentations at the level of understanding, level of interaction, knowledge gained, time management, queries responded, organisation, quality of learning material and overall grading of the educational event. General Practitioners were the key participants in this evaluation and consisted of 60 self-selected physicians distributed equally in both the TBL and lecture groups. Patton's utilization focused model was used to produce findings for effective decision making. The data were analysed using Mann-Whitney U test to know the value of the learning method that satisfied the most participants. A total of 58 evaluations were returned, 29 from the TBL group and 29 from the lecture. The analysis of the elements showed higher mean ranks for TBL method ranging between 32.2 and 38.4 versus lecture (20.6-26.8). Most of the elements assessed were statistically significant (p > 0.05), except time management (p = 0.22). However, elements as 'objectives of the activity met' (p = 0.07), 'overall grading of the event' (p = 0.06) and 'presentations at the level of understanding' (p = 0.06) were at border line. Of the 29 respondents in the TBL group, 75% rated all the elements of the program above very good. In the lecture group, 22 (75%) respondents out of 29 rated almost half of the elements above very good. Majority of respondents in the TBL group rated all program elements as exceptional compared to the lecture group in which only half of the

  13. Modelling and simulation of flight control electromechanical actuators with special focus on model architecting, multidisciplinary effects and power flows

    Institute of Scientific and Technical Information of China (English)

    Fu Jian; Jean-Charles Maré; Fu Yongling

    2017-01-01

    In the aerospace field, electromechanical actuators are increasingly being implemented in place of conventional hydraulic actuators. For safety-critical embedded actuation applications like flight controls, the use of electromechanical actuators introduces specific issues related to thermal balance, reflected inertia, parasitic motion due to compliance and response to failure. Unfortu-nately, the physical effects governing the actuator behaviour are multidisciplinary, coupled and nonlinear. Although numerous multi-domain and system-level simulation packages are now avail-able on the market, these effects are rarely addressed as a whole because of a lack of scientific approaches for model architecting, multi-purpose incremental modelling and judicious model implementation. In this publication, virtual prototyping of electromechanical actuators is addressed using the Bond-Graph formalism. New approaches are proposed to enable incremental modelling, thermal balance analysis, response to free-run or jamming faults, impact of compliance on parasitic motion, and influence of temperature. A special focus is placed on friction and compliance of the mechanical transmission with fault injection and temperature dependence. Aileron actuation is used to highlight the proposals for control design, energy consumption and thermal analysis, power net-work pollution analysis and fault response.

  14. Modelling and simulation of flight control electromechanical actuators with special focus on model architecting, multidisciplinary effects and power flows

    Directory of Open Access Journals (Sweden)

    Jian Fu

    2017-02-01

    Full Text Available In the aerospace field, electromechanical actuators are increasingly being implemented in place of conventional hydraulic actuators. For safety-critical embedded actuation applications like flight controls, the use of electromechanical actuators introduces specific issues related to thermal balance, reflected inertia, parasitic motion due to compliance and response to failure. Unfortunately, the physical effects governing the actuator behaviour are multidisciplinary, coupled and nonlinear. Although numerous multi-domain and system-level simulation packages are now available on the market, these effects are rarely addressed as a whole because of a lack of scientific approaches for model architecting, multi-purpose incremental modelling and judicious model implementation. In this publication, virtual prototyping of electromechanical actuators is addressed using the Bond-Graph formalism. New approaches are proposed to enable incremental modelling, thermal balance analysis, response to free-run or jamming faults, impact of compliance on parasitic motion, and influence of temperature. A special focus is placed on friction and compliance of the mechanical transmission with fault injection and temperature dependence. Aileron actuation is used to highlight the proposals for control design, energy consumption and thermal analysis, power network pollution analysis and fault response.

  15. Model study of multiphase DMS oxidation with a focus on halogens

    Directory of Open Access Journals (Sweden)

    R. von Glasow

    2004-01-01

    Full Text Available We studied the oxidation of dimethylsulfide (DMS in the marine boundary layer (MBL with a one-dimensional numerical model and focused on the influence of halogens. Our model runs show that there is still significant uncertainty about the end products of the DMS addition pathway, which is especially caused by uncertainty in the product yield of the reaction of the intermediate product methyl sulfinic acid (MSIA with OH. BrO strongly increases the importance of the addition branch in the oxidation of DMS even when present at mixing ratios smaller than 0.5pmol mol-1. The inclusion of halogen chemistry leads to higher DMS oxidation rates and smaller DMS to SO2 conversion efficiencies. The DMS to SO2 conversion efficiency is also drastically reduced under cloudy conditions. In cloud-free model runs between 5 and 15% of the oxidized DMS reacts further to particulate sulfur, in cloudy runs this fraction is almost 100%. Sulfate production by HOClaq and HOBraq is important in cloud droplets even for small Br- deficits and related small gas phase halogen concentrations. In general, more particulate sulfur is formed when halogen chemistry is included. A possible enrichment of HCO3- in fresh sea salt aerosol would increase pH values enough to make the reaction of S(IV* (=SO2,aq+HSO3-+SO32- with O3 dominant for sulfate production. It leads to a shift from methyl sulfonic acid (MSA to non-sea salt sulfate (nss-SO42- production but increases the total nss-SO42- only somewhat because almost all available sulfur is already oxidized to particulate sulfur in the base scenario. We discuss how realistic this is for the MBL. We found the reaction MSAaq+OH to contribute about 10% to the production of nss-SO42- in clouds. It is unimportant for cloud-free model runs. Overall we find that the presence of halogens leads to processes that decrease the albedo of stratiform clouds in the MBL.

  16. Gypsy stories: Narrative as a teaching stratagem

    Directory of Open Access Journals (Sweden)

    Čvorović Jelena

    2010-01-01

    could be considered adaptive behavior: disseminating traits that were presumably successful in the past. These stories replicate and describe the environment in which the Gypsy ancestors struggled to survive. As a consequence, the narratives and the Gypsy real world are compatible in many constant and predictable ways, and many Gypsies are hence able to use narrative information/knowledge as a model for proper behavior which helps them to negotiate their social environment in their efforts to survive and reproduce.

  17. USER STORY SOFTWARE ESTIMATION:A SIMPLIFICATION OF SOFTWARE ESTIMATION MODEL WITH DISTRIBUTED EXTREME PROGRAMMING ESTIMATION TECHNIQUE

    OpenAIRE

    Ridi Ferdiana; Paulus Insap Santoso; Lukito Edi Nugroho; Ahmad Ashari

    2011-01-01

    Software estimation is an area of software engineering concerned with the identification, classification and measurement of features of software that affect the cost of developing and sustaining computer programs [19]. Measuring the software through software estimation has purpose to know the complexity of the software, estimate the human resources, and get better visibility of execution and process model. There is a lot of software estimation that work sufficiently in certain conditions or s...

  18. Focused attention vs. crossmodal signals paradigm: Deriving predictions from the time-window-of-integration model

    Directory of Open Access Journals (Sweden)

    Hans eColonius

    2012-08-01

    Full Text Available In the crossmodal signals paradigm (CSP participants are instructed to respond to a set of stimuli from different modalities, presented more or less simultaneously, as soon as a stimulus from any modality has been detected. In the focused attention paradigm (FAP, on the other hand, responses should only be made to a stimulus from a pre-defined target modality and stimuli from non-target modalities should be ignored. Whichever paradigm is being applied, a typical result is that responses tend to be faster to crossmodal stimuli than to unimodal stimuli, a phenomenon often referred to as 'crossmodal interaction'. Here we investigate predictions of the time-window-of-integration (TWIN modeling framework previously proposed by the authors. It is shown that TWIN makes specific qualitative and quantitative predictions on how the two paradigms differ with respect to the probability of multisensory integration and the amount of response enhancement, including the effect of stimulus intensity ('inverse effectiveness'. Introducing a decision-theoretic framework for TWIN further allows comparing the two paradigms with respect to the predicted optimal time window size and its dependence on the prior probability that the crossmodal stimulus information refers to the same event. In order to test these predictions, experimental studies that systematically compare crossmodal effects under stimulus conditions that are identical except for the CSP-FAP instruction should be performed in the future.

  19. Integrative platform based on the mechatronics model for educational technologies focused on competence

    Science.gov (United States)

    Vlaşin, I.; Greta, S.; Dache, L.; Mătieş, V.

    2016-08-01

    Mechatronics is a model of transdisciplinary integration, entirely functional, with remarkable results for mankind. The incredible progress that the global economy has taken in the last decades is based on this new approach, the integrative type, which is present at the foundation of mechatronics. This kind of integrative approach is necessary for building a quality education focused on competence. The requirements from the social and economic environment, the needs of the young people who prepare themselves for an active life and the offers of the education providers are still not too interconnected to offer a satisfying education. This is the reason why the efforts to balance the demand, the needs and the offer are essential to ensure a better integration of students into society. Using a transcultural perspective, we can achieve a constructive approach. The education providers, together with the socio-economic environment, establish a clear structure of competence in multiple domains and of the instruments which can assure it. The scientific demarche, in the spirit of this paper approach the, answers the natural questions from the educational process: „Why, How and What do I learn?”.

  20. Wind mass transfer in S-type symbiotic binaries I. Focusing by the wind compression model

    CERN Document Server

    Skopal, Augustin

    2014-01-01

    Context: Luminosities of hot components in symbiotic binaries require accretion rates that are higher than those that can be achieved via a standard Bondi-Hoyle accretion. This implies that the wind mass transfer in symbiotic binaries has to be more efficient. Aims: We suggest that the accretion rate onto the white dwarfs (WDs) in S-type symbiotic binaries can be enhanced sufficiently by focusing the wind from their slowly rotating normal giants towards the binary orbital plane. Methods: We applied the wind compression model to the stellar wind of slowly rotating red giants in S-type symbiotic binaries. Results: Our analysis reveals that for typical terminal velocities of the giant wind, 20 to 50 km/s, and measured rotational velocities between 6 and 10 km/s, the densities of the compressed wind at a typical distance of the accretor from its donor correspond to the mass-loss rate, which can be a factor of $\\sim$10 higher than for the spherically symmetric wind. This allows the WD to accrete at rates of $10^{-...

  1. Integrating utilization-focused evaluation with business process modeling for clinical research improvement.

    Science.gov (United States)

    Kagan, Jonathan M; Rosas, Scott; Trochim, William M K

    2010-10-01

    New discoveries in basic science are creating extraordinary opportunities to design novel biomedical preventions and therapeutics for human disease. But the clinical evaluation of these new interventions is, in many instances, being hindered by a variety of legal, regulatory, policy and operational factors, few of which enhance research quality, the safety of study participants or research ethics. With the goal of helping increase the efficiency and effectiveness of clinical research, we have examined how the integration of utilization-focused evaluation with elements of business process modeling can reveal opportunities for systematic improvements in clinical research. Using data from the NIH global HIV/AIDS clinical trials networks, we analyzed the absolute and relative times required to traverse defined phases associated with specific activities within the clinical protocol lifecycle. Using simple median duration and Kaplan-Meyer survival analysis, we show how such time-based analyses can provide a rationale for the prioritization of research process analysis and re-engineering, as well as a means for statistically assessing the impact of policy modifications, resource utilization, re-engineered processes and best practices. Successfully applied, this approach can help researchers be more efficient in capitalizing on new science to speed the development of improved interventions for human disease.

  2. Fully Three-dimensional Simulation and Modeling of a Dense Plasma Focus

    CERN Document Server

    Meehan, B T

    2014-01-01

    A Dense Plasma Focus (DPF) is a pulsed-power machine that electromagnetically accelerates and cylindrically compresses a shocked plasma in a Z-pinch. The pinch results in a brief (about 100 nanosecond) pulse of X-rays, and, for some working gases, also a pulse of neutrons. A great deal of experimental research has been done into the physics of DPF reactions, and there exist mathematical models describing its behavior during the different time phases of the reaction. Two of the phases, known as the inverse pinch and the rundown, are approximately governed by magnetohydrodynamics, and there are a number of well-established codes for simulating these phases in two dimensions or in three dimensions under the assumption of axial symmetry. There has been little success, however, in developing fully three-dimensional simulations. In this work we present three-dimensional simulations of DPF reactions and demonstrate that 3D simulations predict qualitatively and quantitatively different behavior than their 2D counterp...

  3. Fully three-dimensional simulation and modeling of a dense plasma focus

    Energy Technology Data Exchange (ETDEWEB)

    Meehan, B. T.; Niederhaus, J. H. J.

    2014-10-01

    A dense plasma focus (DPF) is a pulsed-power machine that electromagnetically accelerates and cylindrically compresses a shocked plasma in a Z-pinch. The pinch results in a brief (~ 100 ns) pulse of X-rays, and, for some working gases, also a pulse of neutrons. A great deal of experimental research has been done into the physics of DPF reactions, and there exist mathematical models describing its behavior during the different time phases of the reaction. Two of the phases, known as the inverse pinch and the rundown, are approximately governed by magnetohydrodynamics, and there are a number of well-established codes for simulating these phases in two dimensions or in three dimensions under the assumption of axial symmetry. There has been little success, however, in developing fully three-dimensional simulations. In this work we present three-dimensional simulations of DPF reactions and demonstrate that three-dimensional simulations predict qualitatively and quantitatively different behavior than their two-dimensional counterparts. One of the most important quantities to predict is the time duration between the formation of the gas shock and Z-pinch, and the three-dimensional simulations more faithfully represent experimental results for this time duration and are essential for accurate prediction of future experiments.

  4. "Stories Take Your Role Away From You": Understanding the Impact on Health Care Professionals of Viewing Digital Stories of Pediatric and Adolescent/Young Adult Oncology Patients.

    Science.gov (United States)

    Laing, Catherine M; Moules, Nancy J; Estefan, Andrew; Lang, Mike

    The purpose of this philosophical hermeneutic study was to understand the effects on health care providers (HCPs) of watching digital stories made by (past and present) pediatric and adolescent/young adult (AYA) oncology patients. Twelve HCPs participated in a focus group where they watched digital stories made by pediatric/AYA oncology patients and participated in a discussion related to the impact the stories had on them personally and professionally. Findings from this research revealed that HCPs found digital stories to be powerful, therapeutic, and educational tools. Health care providers described uses for digital stories ranging from education of newly diagnosed families to training of new staff. Digital stories, we conclude, can be an efficient and effective way through which to understand the patient experience, implications from which can range from more efficient patient care delivery to decision making. Recommendations for incorporating digital storytelling into healthcare delivery are offered.

  5. Modeling and experimental investigations of Lamb waves focusing in anisotropic plates

    Energy Technology Data Exchange (ETDEWEB)

    Chapuis, Bastien [Departement Materiaux et Structures Composites, ONERA, 29 avenue de la Division Leclerc, 92322 Chatillon Cedex (France); Terrien, Nicolas [CETIM, 74 route de la Joneliere, 44326 Nantes Cedex 3 (France); Royer, Daniel, E-mail: Bastien.Chapuis@onera.fr [Laboratoire Ondes et Acoustique, ESPCI, Universite Paris 7, CNRS UMR 7587, 10 rue Vauquelin, 75231 Paris Cedex 05 (France)

    2011-01-01

    The phenomenon of Lamb waves focusing in anisotropic plates is theoretically and experimentally investigated. An analysis based on a far field approximation of the Green's function shows that Lamb waves focusing is analog to the phonon focusing effect. In highly anisotropic structures like composite plates the focusing of A{sub 0} and S{sub 0} mode is strong; the energy propagates preferentially in the fibre directions, which are minima of the slowness. This has to be taken into account when developing, for example, a transducer array for structural health monitoring systems based on Lamb waves in order to avoid dead zones.

  6. Ghost-Story Telling: Keeping It Appropriate.

    Science.gov (United States)

    Weintraub, Jeff

    1996-01-01

    Guidelines for telling ghost stories at camp involve considering children's fears at different ages, telling age appropriate stories, determining appropriate times for telling ghost stories, and minimizing fear when a child becomes frightened by a ghost story. Includes tips on the selection, preparation, and presentation of ghost stories. (LP)

  7. Setting boundary conditions on the Khokhlov-Zabolotskaya equation for modeling ultrasound fields generated by strongly focused transducers

    Science.gov (United States)

    Rosnitskiy, P. B.; Yuldashev, P. V.; Vysokanov, B. A.; Khokhlova, V. A.

    2016-03-01

    An equivalent source model is developed for setting boundary conditions on the parabolic diffraction equation in order to simulate ultrasound fields radiated by strongly focused medical transducers. The equivalent source is defined in a plane; corresponding boundary conditions for pressure amplitude, aperture, and focal distance are chosen so that the axial solution to the parabolic model in the focal region of the beam matches the solution to the full diffraction model (Rayleigh integral) for a spherically curved uniformly vibrating source. It is shown that the proposed approach to transferring the boundary condition from a spherical surface to a plane makes it possible to match the solutions over an interval of several diffraction maxima around the focus even for focused sources with F-numbers less than unity. This method can be used to accurately simulate nonlinear effects in the fields of strongly focused therapeutic transducers using the parabolic Khokhlov-Zabolotskaya equation.

  8. USER STORY SOFTWARE ESTIMATION:A SIMPLIFICATION OF SOFTWARE ESTIMATION MODEL WITH DISTRIBUTED EXTREME PROGRAMMING ESTIMATION TECHNIQUE

    Directory of Open Access Journals (Sweden)

    Ridi Ferdiana

    2011-01-01

    Full Text Available Software estimation is an area of software engineering concerned with the identification, classification and measurement of features of software that affect the cost of developing and sustaining computer programs [19]. Measuring the software through software estimation has purpose to know the complexity of the software, estimate the human resources, and get better visibility of execution and process model. There is a lot of software estimation that work sufficiently in certain conditions or step in software engineering for example measuring line of codes, function point, COCOMO, or use case points. This paper proposes another estimation technique called Distributed eXtreme Programming Estimation (DXP Estimation. DXP estimation provides a basic technique for the team that using eXtreme Programming method in onsite or distributed development. According to writer knowledge this is a first estimation technique that applied into agile method in eXtreme Programming.

  9. Pathogenesis, Experimental Models and Contemporary Pharmacotherapy of Irritable Bowel Syndrome: Story About the Brain-Gut Axis

    Science.gov (United States)

    Tsang, S.W.; Auyeung, K.K.W.; Bian, Z.X.; Ko, J.K.S.

    2016-01-01

    Background Although the precise pathophysiology of irritable bowel syndrome (IBS) remains unknown, it is generally considered to be a disorder of the brain-gut axis, representing the disruption of communication between the brain and the digestive system. The present review describes advances in understanding the pathophysiology and experimental approaches in studying IBS, as well as providing an update of the therapies targeting brain-gut axis in the treatment of the disease. Methods Causal factors of IBS are reviewed. Following this, the preclinical experimental models of IBS will be introduced. Besides, both current and future therapeutic approaches of IBS will be discussed. Results When signal of the brain-gut axis becomes misinterpreted, it may lead to dysregulation of both central and enteric nervous systems, altered intestinal motility, increased visceral sensitivity and consequently contributing to the development of IBS. Interference of the brain-gut axis can be modulated by various psychological and environmental factors. Although there is no existing animal experiment that can represent this complex multifactorial disease, these in vivo models are clinically relevant readouts of gastrointestinal functions being essential to the identification of effective treatments of IBS symptoms as well as their molecular targets. Understanding the brain-gut axis is essential in developing the effective therapy for IBS. Therapies include improvement of GI motor functions, relief of visceral hypersensitivity and pain, attenuation of autonomic dysfunctions and suppression of mucosal immune activation. Conclusion Target-oriented therapies that provide symptomatic, psychological and physiological benefits could surely help to improve the quality of life of IBS patients. PMID:27009115

  10. Focused ultrasound simultaneous irradiation/MRI imaging, and two-stage general kinetic model.

    Directory of Open Access Journals (Sweden)

    Sheng-Yao Huang

    Full Text Available Many studies have investigated how to use focused ultrasound (FUS to temporarily disrupt the blood-brain barrier (BBB in order to facilitate the delivery of medication into lesion sites in the brain. In this study, through the setup of a real-time system, FUS irradiation and injections of ultrasound contrast agent (UCA and Gadodiamide (Gd, an MRI contrast agent can be conducted simultaneously during MRI scanning. By using this real-time system, we were able to investigate in detail how the general kinetic model (GKM is used to estimate Gd penetration in the FUS irradiated area in a rat's brain resulting from UCA concentration changes after single FUS irradiation. Two-stage GKM was proposed to estimate the Gd penetration in the FUS irradiated area in a rat's brain under experimental conditions with repeated FUS irradiation combined with different UCA concentrations. The results showed that the focal increase in the transfer rate constant of Ktrans caused by BBB disruption was dependent on the doses of UCA. Moreover, the amount of in vivo penetration of Evans blue in the FUS irradiated area in a rat's brain under various FUS irradiation experimental conditions was assessed to show the positive correlation with the transfer rate constants. Compared to the GKM method, the Two-stage GKM is more suitable for estimating the transfer rate constants of the brain treated with repeated FUS irradiations. This study demonstrated that the entire process of BBB disrupted by FUS could be quantitatively monitored by real-time dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI.

  11. Maximum Potential Score (MPS: An operating model for a successful customer-focused strategy.

    Directory of Open Access Journals (Sweden)

    Cabello González, José Manuel

    2015-11-01

    Full Text Available One of marketers’ chief objectives is to achieve customer loyalty, which is a key factor for profitable growth. Therefore, they need to develop a strategy that attracts and maintains customers, giving them adequate motives, both tangible (prices and promotions and intangible (personalized service and treatment, to satisfy a customer and make him loyal to the company. Finding a way to accurately measure satisfaction and customer loyalty is very important. With regard to typical Relationship Marketing measures, we can consider listening to customers, which can help to achieve a competitive sustainable advantage. Customer satisfaction surveys are essential tools for listening to customers. Short questionnaires have gained considerable acceptance among marketers as a means to achieve a customer satisfaction measure. Our research provides an indication of the benefits of a short questionnaire (one/three questions. We find that the number of questions survey is significantly related to the participation in the survey (Net Promoter Score or NPS. We also prove that a the three question survey is more likely to have more participants than a traditional survey (Maximum Potential Score or MPS . Our main goal is to analyse one method as a potential predictor of customer loyalty. Using surveys, we attempt to empirically establish the causal factors in determining the satisfaction of customers. This paper describes a maximum potential operating model that captures with a three questions survey, important elements for a successful customer-focused strategy. MPS may give us lower participation rates than NPS but important information that helps to convert unhappy customers or just satisfied customers, into loyal customers.

  12. Community pediatrics: the Rochester story.

    Science.gov (United States)

    Haggerty, Robert J; Aligne, C Andrew

    2005-04-01

    There are so many problems facing children today (eg, violence, poor nutrition, substance abuse, teen pregnancy) that conventional medical care can only address a small portion of these concerns. Thus, to be optimally effective, pediatrics needs to be linked to other disciplines and programs that address these issues by using different paradigms. Robert Haggerty, the originator of the term "community pediatrics," reflects on how one can successfully practice community pediatrics in an academic setting and model it for young physicians while also improving the health of children at the community level. Here we tell the story of the years that Haggerty was chief of pediatrics at the University of Rochester and took on the challenge of fulfilling the department's responsibility to all children in the county. Because of his pioneering work, his tenure was heralded as a critical period in the development of the field of community pediatrics.

  13. A compendium of energy conservation success stories

    Energy Technology Data Exchange (ETDEWEB)

    1988-09-01

    Three-quarters of DOE's Conservation R and D funds have been devoted to technology research and development: basic and applied research, exploratory R and D, engineering feasibility studies, pilot-scale prototype R and D, and technology demonstration. Non R and D projects have involved technology assessment program planning and analysis, model development, technology transfer and consumer information, health effects and safety research, and technical support for rule making. The success stories summarized in this compendium fall into three general categories: Completed Technology Success Stories, projects that have resulted in new energy-saving technologies that are presently being used in the private sector; Technical Success Stories, projects that have produced or disseminated important scientific/technical information likely to result in future energy savings; Program Success Stories, non-R and D activities that have resulted in nationally significant energy benefits. The Energy Conservation research and development program at DOE is managed by the Office of Conservation under the direction of the Deputy Assistant Secretary for Conservation. Three subordinate Program Offices correspond to the buildings, transportation, and industrial end-use sectors. A fourth subordinate Program Office/endash/Energy Utilization Research/endash/sponsors research and technical inventions for all end-use sectors.

  14. A Compendium of Energy Conservation Success Stories

    Science.gov (United States)

    1988-09-01

    Three-quarters of DOE's Conservation R and D funds have been devoted to technology research and development: basic and applied research, exploratory R and D, engineering feasibility studies, pilot-scale prototype R and D, and technology demonstration. Non R and D projects have involved technology assessment program planning and analysis, model development, technology transfer and consumer information, health effects and safety research, and technical support for rule making. The success stories summarized in this compendium fall into three general categories: Completed Technology Success Stories, projects that have resulted in new energy-saving technologies that are presently being used in the private sector; Technical Success Stories, projects that have produced or disseminated important scientific/technical information likely to result in future energy savings; Program Success Stories, non-R and D activities that have resulted in nationally significant energy benefits. The Energy Conservation research and development program at DOE is managed by the Office of Conservation under the direction of the Deputy Assistant Secretary for Conservation. Three subordinate Program Offices correspond to the buildings, transportation, and industrial end-use sectors. A fourth subordinate Program Office{endash}Energy Utilization Research{endash}sponsors research and technical inventions for all end-use sectors.

  15. An International Inquiry: Stories of Poverty--Poverty Stories

    Science.gov (United States)

    Ciuffetelli Parker, Darlene; Craig, Cheryl J.

    2017-01-01

    This article features an international inquiry of two high-poverty urban schools, one Canadian and one American. The article examines poverty in terms of "small stories" that educators and students live and tell, often on the edges, unheard and unaccounted for in grand narratives. It also expands the story constellations approach to…

  16. An International Inquiry: Stories of Poverty--Poverty Stories

    Science.gov (United States)

    Ciuffetelli Parker, Darlene; Craig, Cheryl J.

    2017-01-01

    This article features an international inquiry of two high-poverty urban schools, one Canadian and one American. The article examines poverty in terms of "small stories" that educators and students live and tell, often on the edges, unheard and unaccounted for in grand narratives. It also expands the story constellations approach to…

  17. FUNDAMENTAL AREAS OF PHENOMENOLOGY (INCLUDING APPLICATIONS): Modeling of Nonlinear Propagation in Multi-layer Biological Tissues for Strong Focused Ultrasound

    Science.gov (United States)

    Fan, Ting-Bo; Liu, Zhen-Bo; Zhang, Zhe; Zhang, Dong; Gong, Xiu-Fen

    2009-08-01

    A theoretical model of the nonlinear propagation in multi-layered tissues for strong focused ultrasound is proposed. In this model, the spheroidal beam equation (SBE) is utilized to describe the nonlinear sound propagation in each layer tissue, and generalized oblique incidence theory is used to deal with the sound transmission between two layer tissues. Computer simulation is performed on a fat-muscle-liver tissue model under the irradiation of a 1 MHz focused transducer with a large aperture angle of 35°. The results demonstrate that the tissue layer would change the amplitude of sound pressure at the focal region and cause the increase of side petals.

  18. Pediatric Palliative Care: A Personal Story

    Medline Plus

    Full Text Available ... Queue Queue __count__/__total__ Find out why Close Pediatric Palliative Care: A Personal Story NINRnews Loading... Unsubscribe ... This vignette shares the story of Rachel—a pediatric neuroblastoma patient—and her family. The story demonstrates ...

  19. Story: A Bleeding Watermelon

    Directory of Open Access Journals (Sweden)

    Nor bzang

    2010-12-01

    Full Text Available A Bleeding Watermelon was written by Norsang (Nor bzang;b. 1988, a native of Dpa ris (Rab rgyas (Huazangsi 华藏寺 Township, Tianzhu 天祝 Tibetan Autonomous County,Gansu 甘肃 Province. Norsang writes: I heard that a university student opened an elevator door in a campus building still under construction. The elevator shaft was empty and he fell to his death. Many people had questions about his death. This inspired me to write this story.

  20. Telling life stories.

    Science.gov (United States)

    Sorrell, Jeanne M; Butler, Frieda R

    2009-11-01

    A life review has been demonstrated to be highly beneficial to well or chronically ill older adults, as well as terminally ill older adults. Those living independently indicate feelings of relief and connectivity after telling their stories. Further, terminally ill patients at the end of their lives express feelings of peacefulness at being able to put pieces of their lives together in a meaningful way. It is well known that physicians and nurses have received inadequate training in how to address end-of-life issues. The life review process can be an important strategy for fostering helpful communication between health care professionals and older adults in all phases of health and illness.

  1. Stories in the Data.

    Science.gov (United States)

    Singh, Gary

    2017-01-01

    To some degree, comics have always been used to convert data into stories, from ancient Egyptian heiroglyphics to crude biology diagrams in grade-school textbooks. By their very nature, comics communicate through a variety of visualization techniques. Benjamin Bach, who along with his coauthors Nathalie Henry Riche, Sheelagh Carpendale, and Hanspeter Pfister created this issue's Art on Graphics special contribution about the emerging genre of data comics, here talks about their attempts to leverage the massive untapped potential for data-driven comics to explain multiple threads of simultaneous data.

  2. From Doctors' Stories to Doctors' Stories, and Back Again.

    Science.gov (United States)

    Childress, Marcia Day

    2017-03-01

    Stories have always been central to medicine, but during the twentieth century bioscience all but eclipsed narrative's presence in medical practice. In Doctors' Stories, published in 1991, Kathryn Montgomery excavated medicine's narrative foundations and functions to reveal new possibilities for how to conceive and characterize medicine. Physicians' engagement with stories has since flourished, especially through the narrative medicine movement, although in the twenty-first century this has been challenged by the health care industry's business-minded and data-driven clinical systems. But doctors' stories-and Montgomery's text-remain crucial, schooling clinicians in reflection, ethical awareness, and resilience. Physicians who write even short, 55-word reflective stories can hold to humanistic and ethical understandings of patient care and of themselves as healers even as they practice in systematized settings and employ evidence-based expertise. © 2017 American Medical Association. All Rights Reserved.

  3. The StorySpinner Sculptural Reader

    OpenAIRE

    Hooper, Clare; Weal, Mark

    2005-01-01

    This demo is of a hypertext reading system called StorySpinner. It follows the sculptural hypertext methodology and has been used as a test bed for experimenting with the authoring of narrative flow in automatically generated stories. Readers are able to select and read one of two available stories. Reading a story involves selecting tarot cards which are mapped to chunks of story text based on possible interpretations of the cards and information concerning current story state.

  4. Linking Resource-Based Strategies to Customer-Focused Performance for Professional Services: A Structural Equation Modelling Approach

    Directory of Open Access Journals (Sweden)

    Ming-Lu Wu

    2013-12-01

    Full Text Available This paper links professional service firms’ resource-based strategies to their customer-focused performance for formulating service quality improvement priorities. The research applies the structural equation modelling approach to survey data from Hong Kong construction consultants to test some hypotheses. The study validates the various measures of firms’ resource-based strategies and customer-focused performance and bridges the gaps in firms’ organizational learning, core competences and customer-focused performance mediated by their strategic flexibility. The research results have practical implications for professional service firms to deploy resources appropriately to first enhance different competences and then improve customerfocused performance using their different competences.

  5. Relaxation and Visualization Strategies for Story Telling

    Institute of Scientific and Technical Information of China (English)

    冯灵林

    2012-01-01

    The importance of training students to tell or retell story is self - evident for mastering English language. The following activity introduces relaxation and visualization strategies for story telling.

  6. USE OF THE STORIES FORMED WITH DRAMA IN TURKISH EDUCATION

    Directory of Open Access Journals (Sweden)

    Ömer Tuğrul KARA

    2013-06-01

    Full Text Available New Turkish Program has been based upon activities that will provide participation of students to the educational process. Story formation with drama which is one of the most suitable activities to actualize requirements of the Turkish education is to animate improvised or proverbial stories using drama techniques. What has been meant with the expression of story formation in drama studies is to accommodate story genre into animation of other genres including texts based upon events rather than dramatization of the genre’s itself. Through the animation of the story, the student will have the opportunity of examining, analyzing and solving the problems related to real life. While concepts such as hero, target, obstacle /event have been the primary elements of story formation, concepts such as speech line and metaxis are the secondary elements. There can be provided the acquisition of four basic language abilities to be actualized, association of linguistic concepts with daily life and exposure of a hidden ability into the light through the stories formed with drama in Turkish lessons. This study has been carried out using the scanning model and relevant researches within the bounds of the subject have been benefited.

  7. The psychology of telling murder stories: do we think in scripts, exemplars, or prototypes?

    Science.gov (United States)

    Wiener, Richard L; Richmond, Tracey L; Seib, Hope M; Rauch, Shannon M; Hackney, Amy A

    2002-01-01

    According to the story model of Pennington and Hastie, jurors collect information at trial and modify it with general knowledge to create case stories. Schank and Ableson argue that human memory is organized to tell and understand stories. However, Finkel and Groscup questioned the use of manipulated, experimenter-constructed narratives to demonstrate the existence of multiple prototypical crime stories. We interviewed 76 jury eligible, death qualified citizens and asked them to imagine a first-degree murder scenario, describing the events that led to the killing. We coded the presence of dichotomous variables in the resulting stories and identified at least three shared story prototypes using cluster and profile analysis. We conclude that people do not store crime stories as simple prototypes and comment on the implications of this finding for legal decision-making.

  8. Numerical modeling of the Joule heating effect on electrokinetic flow focusing.

    Science.gov (United States)

    Huang, Kuan-Da; Yang, Ruey-Jen

    2006-05-01

    In electrokinetically driven microfluidic systems, the driving voltage applied during operation tends to induce a Joule heating effect in the buffer solution. This heat source alters the solution's characteristics and changes both the electrical potential field and the velocity field during the transport process. This study performs a series of numerical simulations to investigate the Joule heating effect and analyzes its influence on the electrokinetic focusing performance. The results indicate that the Joule heating effect causes the diffusion coefficient of the sample to increase, the potential distribution to change, and the flow velocity field to adopt a nonuniform profile. These variations are particularly pronounced under tighter focusing conditions and at higher applied electrical intensities. In numerical investigations, it is found that the focused bandwidth broadens because thermal diffusion effect is enhanced by Joule heating. The variation in the potential distribution induces a nonuniform flow field and causes the focused bandwidth to tighten and broaden alternately as a result of the convex and concave velocity flow profiles, respectively. The present results confirm that the Joule heating effect exerts a considerable influence on the electrokinetic focusing ratio.

  9. The Power of Story in an Animation Industry

    Directory of Open Access Journals (Sweden)

    Kadek Satria Adidharma

    2011-03-01

    Full Text Available After the founding of the Walt Disney Company, animation becomes something necessary in our everyday life. The real power why the animation bigger is the storytelling. Story is the main key why animation is loveable by audiences. This writing will be focusing on the behind reason why the story is important in animation and will be giving some examples the success story of some animation which have a great story to tell. The design methodology focuses on data research, market research and literature book. This writing is a preliminary research because from the author concern, there are not many writings debating whether which part in the development will be focused on to developing some animation projects. This writing hopefully will help people who want to build some animation projects and will guide them to make decision because in order to build some animation project there will be a massive effort to be conducted. Hopefully, in the future, there will be more animation produced from Indonesian. To be an unforgettable work, it must have a great story.

  10. The Power of Story in an Animation Industry

    Directory of Open Access Journals (Sweden)

    Kadek Satria Adidharma

    2011-04-01

    Full Text Available After the founding of the Walt Disney Company, animation becomes something necessary in our everyday life. The real power why the animation bigger is the storytelling. Story is the main key why animation is loveable by audiences. This writing will be focusing on the behind reason why the story is important in animation and will be giving some examples the success story of some animation which have a great story to tell. The design methodology focuses on data research, market research and literature book. This writing is a preliminary research because from the author concern, there are not many writings debating whether which part in the development will be focused on to developing some animation projects. This writing hopefully will help people who want to build some animation projects and will guide them to make decision because in order to build some animation project there will be a massive effort to be conducted. Hopefully, in the future, there will be more animation produced from Indonesian. To be an unforgettable work, it must have a great story.

  11. CAE "FOCUS" for modelling and simulating electron optics systems: development and application

    Science.gov (United States)

    Trubitsyn, Andrey; Grachev, Evgeny; Gurov, Victor; Bochkov, Ilya; Bochkov, Victor

    2017-02-01

    Electron optics is a theoretical base of scientific instrument engineering. Mathematical simulation of occurring processes is a base for contemporary design of complicated devices of the electron optics. Problems of the numerical mathematical simulation are effectively solved by CAE system means. CAE "FOCUS" developed by the authors includes fast and accurate methods: boundary element method (BEM) for the electric field calculation, Runge-Kutta- Fieghlberg method for the charged particle trajectory computation controlling an accuracy of calculations, original methods for search of terms for the angular and time-of-flight focusing. CAE "FOCUS" is organized as a collection of modules each of which solves an independent (sub) task. A range of physical and analytical devices, in particular a microfocus X-ray tube of high power, has been developed using this soft.

  12. A focused crawler combinatory link and content model based on T-graph principles

    OpenAIRE

    Seyfi, Ali; Patel, Ahmed

    2016-01-01

    The two significant tasks of a focused Web crawler are finding relevant topic-specific documents on the Web and analytically prioritizing them for later effective and reliable download. For the first task, we propose a sophisticated custom algorithm to fetch and analyze the most effective HTML structural elements of the page as well as the topical boundary and anchor text of each unvisited link, based on which the topical focus of an unvisited page can be predicted and elicited with a high ac...

  13. Local meanings of a sport mega-event's legacies : Stories from a South African urban neighbourhood

    NARCIS (Netherlands)

    Waardenburg, Maikel; van den Bergh, Marjolein; van Eekeren, Frank

    2015-01-01

    Studies on sport mega-events and their legacies often seem only loosely connected to local experiences. Stories on sport mega-event legacy appear as a setting-the-scene or function as a reference to illustrate specific types of legacy. However, stories themselves are never the primary focus in these

  14. The 2011 NCTE Presidential Address: Telling Our Stories ("Ka Ha'i Mo'olelo 'Ana")

    Science.gov (United States)

    Siu-Runyan, Yvonne

    2012-01-01

    This article presents the author's presidential address, delivered at the NCTE Annual Convention in Chicago, Illinois, on November 20, 2011. The author focuses on the powerful stories that define educators. The author's point is that telling one's story is one of the most important things an educator can do for those he/she teaches as well as for…

  15. Joan Aiken's Armitage Family Stories: Place and Storytelling as a Way into the World

    Science.gov (United States)

    Sackett, Hannah

    2012-01-01

    This article explores the importance of place and story in the life and work of Joan Aiken (1924-2004), with a focus on the Armitage Family short stories. It explores the fluid relationship between books, storytelling and place in Joan Aiken's childhood and looks at her close relationship with the landscape of the Sussex Downs. Particular…

  16. Teacher Counter Stories to a Citizenship Education Mega Policy Narrative. Preparing for Citizenship in Chile

    Science.gov (United States)

    Cavieres-Fernández, Eduardo

    2017-01-01

    The present article focuses on the counter stories of two Chilean social studies high school teachers. Counter stories describe how teachers use their professional experience to confront those mega narratives composed of dominant educational policies that impinge upon their pedagogical practices. The mega narrative described in this study as a…

  17. The Dangers of the Single Story: Child-Soldiers in Literary Fiction and Film

    Science.gov (United States)

    Martins, Catarina

    2011-01-01

    Focusing on the paradox between innocence and responsibility generated by the term child-soldiers, which is treated differently in literary and cinematographic works from the North and the South, this article uses postcolonial theory in order to deconstruct "the single story" that may be erasing these children's many stories.…

  18. Storied Selves: A Critical Discourse Analysis of Young Children's Literate Identifications

    Science.gov (United States)

    Rogers, Rebecca; Elias, Martille

    2012-01-01

    A wealth of research demonstrates that as young children acquire literacy they also approximate literate roles and relationships. Such literate identifications, or storied selves, are complex, sometimes contradictory and under construction for young people. Less research has focused on "how" young children's storied selves are…

  19. "They Kicked Him Out": Teachers' Student Stories as Counterstories

    Science.gov (United States)

    Downey, C. Aiden

    2015-01-01

    This article focuses on teachers' identity construction in the context of a "failing" inner-city high school. Framing teachers' student stories as narrative resources for solving both the practical and identity problems that confront them in an underresourced, inner-city school, the article argues that these stories can serve…

  20. Non-uniform hybrid strategy for architecting and modeling flight vehicle focused system-of-systems operations

    Institute of Scientific and Technical Information of China (English)

    Tian Yifeng; Liu Hu; Luo Mingqiang; Huang Jun

    2016-01-01

    To balance the contradiction between comprehensiveness of system-of-systems (SoS) description and cost of modeling and simulation, a non-uniform hybrid strategy (NUHYS) is pro-posed. NUHYS groups elements of an SoS operation into system community or relatively indepen-dent system based on contributors complexity and focus relationship according to the focus of SoS problem. Meanwhile, modeling methods are categorized based on details attention rate and dynamic attention rate, seeking for matching contributors. Taking helicopter rescue in earthquake relief as an example, the procedure of applying NUHYS and its effectiveness are verified.

  1. Non-uniform hybrid strategy for architecting and modeling flight vehicle focused system-of-systems operations

    Directory of Open Access Journals (Sweden)

    Tian Yifeng

    2016-02-01

    Full Text Available To balance the contradiction between comprehensiveness of system-of-systems (SoS description and cost of modeling and simulation, a non-uniform hybrid strategy (NUHYS is proposed. NUHYS groups elements of an SoS operation into system community or relatively independent system based on contributors complexity and focus relationship according to the focus of SoS problem. Meanwhile, modeling methods are categorized based on details attention rate and dynamic attention rate, seeking for matching contributors. Taking helicopter rescue in earthquake relief as an example, the procedure of applying NUHYS and its effectiveness are verified.

  2. Comparison of models for predicting outcomes in patients with coronary artery disease focusing on microsimulation

    Directory of Open Access Journals (Sweden)

    Masoud Amiri

    2012-01-01

    Full Text Available Background: Physicians have difficulty to subjectively estimate the cardiovascular risk of their patients. Using an estimate of global cardiovascular risk could be more relevant to guide decisions than using binary representation (presence or absence of risk factors data. The main aim of the paper is to compare different models of predicting the progress of a coronary artery diseases (CAD to help the decision making of physician. Methods: There are different standard models for predicting risk factors such as models based on logistic regression model, Cox regression model, dynamic logistic regression model, and simulation models such as Markov model and microsimulation model. Each model has its own application which can or cannot use by physicians to make a decision on treatment of each patient. Results: There are five main common models for predicting of outcomes, including models based on logistic regression model (for short-term outcomes, Cox regression model (for intermediate-term outcomes, dynamic logistic regression model, and simulation models such as Markov and microsimulation models (for long-term outcomes. The advantages and disadvantages of these models have been discussed and summarized. Conclusion: Given the complex medical decisions that physicians face in everyday practice, the multiple interrelated factors that play a role in choosing the optimal treatment, and the continuously accumulating new evidence on determinants of outcome and treatment options for CAD, physicians may potentially benefit from a clinical decision support system that accounts for all these considerations. The microsimulation model could provide cardiologists, researchers, and medical students a user-friendly software, which can be used as an intelligent interventional simulator.

  3. Enhancement of Entrepreneurial Leadership: A Case Focusing on a Model of Successful Conflict Management Skills

    Science.gov (United States)

    Leffel, Anita; Hallam, Cory; Darling, John

    2012-01-01

    The purpose of this paper is to present a case study focusing on a new technology start-up firm, founded by two graduate students, an engineer and a business major, who met during their university studies. The case is timely, in that only ten percent of new product introductions result in a profitable business. The causes of failure are numerous…

  4. A Hierarchical Model for Language Maintenance and Language Shift: Focus on the Malaysian Chinese Community

    Science.gov (United States)

    Wang, Xiaomei; Chong, Siew Ling

    2011-01-01

    Social factors involved in language maintenance and language shift (LMLS) have been the focus of LMLS studies. Previous studies provide fundamental support for the theoretical development of this research branch. However, there is no discussion regarding the hierarchical order of these social factors, i.e. the degree of importance of various…

  5. Focal Points on Constructing News Stories

    Directory of Open Access Journals (Sweden)

    Elena Yuryevna Ilyinova

    2015-11-01

    Full Text Available The issues stated in the article line with the current interest to pragmatic value of news releases in modern media. The news is thought to be a verbalized focal reflection of some event that was chosen by media professionals for setting the current information agenda. Having generated the opinions on the newsworthiness the authors present a set of values that may be used for measurement of relevance and clarity of an event reflection in the news content with frequency, clarity, predictability, unexpectedness, amplitude, cultural proximity, elite nations, elite people, personification, negativity among them. The novelty of the research is that the newsworthiness is checked with the focus to lexical (thematic representation of the news in a diachronic approach: the empirical base of the research was taken from the archives of UK national and local media sources (18–20th cent. and implied comparison of lexical means that reflected an event itself and some values of human interest potential in the news stories written in defined periods. The article states the trend for dynamics in the way the event is reflected in the news stories – the information core of the story is merged with detailed reporting parts, and their content is conditioned by social and moral values.

  6. StoryTrek: Experiencing Stories in the Real World

    DEFF Research Database (Denmark)

    Khaled, Rilla; Barr, Pippin James; Greenspan, Brian

    2011-01-01

    In this paper we introduce StoryTrek, a locative hypernarrative system developed to generate stories based on a reader’s location and specific movements in the real world. This creates, for readers, an interplay between navigation, narrative, and agency, as well as between the fictional and real...... world experience. In early tests we observed the emergence of a number of recurrent themes in participants’ experiences which are characteristic of the StoryTrek system, but which also help us to understand locative media storytelling affordances more generally. In this paper we present the system...

  7. Modelling Systems of Classical/Quantum Identical Particles by Focusing on Algorithms

    Science.gov (United States)

    Guastella, Ivan; Fazio, Claudio; Sperandeo-Mineo, Rosa Maria

    2012-01-01

    A procedure modelling ideal classical and quantum gases is discussed. The proposed approach is mainly based on the idea that modelling and algorithm analysis can provide a deeper understanding of particularly complex physical systems. Appropriate representations and physical models able to mimic possible pseudo-mechanisms of functioning and having…

  8. Tangible Modelling to Elicit Domain Knowledge: An Experiment and Focus Group

    NARCIS (Netherlands)

    Ionita, Dan; Wieringa, Roelf J.; Bullee, Jan-Willem; Vasenev, Alexandr; Johannesson, Paul; Li Lee, Mong; Liddle, Stephen W.; Opdahl, Andreas L.; López, Óscar Pastor

    2015-01-01

    Conceptual models represent social and technical aspects of the world relevant to a variety of technical and non-technical stakehold- ers. To build these models, knowledge might have to be collected from domain experts who are rarely modelling experts and don’t usually have the time or desire to

  9. Modelling Systems of Classical/Quantum Identical Particles by Focusing on Algorithms

    Science.gov (United States)

    Guastella, Ivan; Fazio, Claudio; Sperandeo-Mineo, Rosa Maria

    2012-01-01

    A procedure modelling ideal classical and quantum gases is discussed. The proposed approach is mainly based on the idea that modelling and algorithm analysis can provide a deeper understanding of particularly complex physical systems. Appropriate representations and physical models able to mimic possible pseudo-mechanisms of functioning and having…

  10. Dispersed plug flow model for upflow anaerobic sludge bed reactors with focus on granular sludge dynamics

    NARCIS (Netherlands)

    Kalyuzhnyi, S.V.; Fedorovich, V.V.; Lens, P.N.L.

    2006-01-01

    A new approach to model upflow anaerobic sludge bed (UASB)-reactors, referred to as a one-dimensional dispersed plug flow model, was developed. This model focusses on the granular sludge dynamics along the reactor height, based on the balance between dispersion, sedimentation and convection using on

  11. A Little Solar Story

    DEFF Research Database (Denmark)

    Ahmad, Bashir

    1997-01-01

    Experiences from use of solar cookers in India and many other places are different. But the story which is based on a field study in Gujarat state of India shows that during last twenty years there has been a tendency that many families do not continue to use their solar cookers. The study shows...... that the tendency is related with the lack of compatibility of this new technology (solar cooker) with the everyday real-life conditions of the families. In principle the findings are supported by an evaluation report on a solar cooker project in Burkina Faso. The conclusion is that the user should be involved...... in the solar cooker technological development process....

  12. Story and Real Life

    Directory of Open Access Journals (Sweden)

    Robert P. Waxler

    2013-06-01

    Full Text Available Why should we be concerned about the fate of literature as we move from a book culture to a screen culture in the digital age? Not primarily because we are losing our sense of story, but because we are losing our sense of the central importance of linguistic narrative. There is a difference. The technologies creating the digital revolution seem to devalue language and increasingly to do away with boundaries, celebrating instead speed and boundless exhilaration. The visual trumps the linguistic, the image and the screen trump the word and the book. As a result, we no longer seem to engage deeply with others or ourselves. We are beginning to move, in other words, from “a reading brain” to “a digital brain,” from a brain capable of deep reading and deep thinking to a brain increasingly addled by spectacle and surface sensation. We are losing our standing as “linguistic beings.”

  13. Story and Real Life

    Directory of Open Access Journals (Sweden)

    Robert P. Waxler

    2013-06-01

    Full Text Available Why should we be concerned about the fate of literature as we move from a book culture to a screen culture in the digital age? Not primarily because we are losing our sense of story, but because we are losing our sense of the central importance of linguistic narrative. There is a difference. The technologies creating the digital revolution seem to devalue language and increasingly to do away with boundaries, celebrating instead speed and boundless exhilaration. The visual trumps the linguistic, the image and the screen trump the word and the book. As a result, we no longer seem to engage deeply with others or ourselves. We are beginning to move, in other words, from “a reading brain” to “a digital brain,” from a brain capable of deep reading and deep thinking to a brain increasingly addled by spectacle and surface sensation. We are losing our standing as “linguistic beings.”

  14. The Singapore research story

    CERN Document Server

    Teck Seng, Low; Thampuran, Raj

    2016-01-01

    Ever since Singapore became independent in 1965, its leaders have invested tremendous efforts and resources to develop its economy in order to create jobs for its people and to support national development. This book describes the challenging journey of Singapore in developing a knowledge-based economy driven by research and innovation and the roles played by research institutes, universities, research manpower and appropriate collaboration between research institutes and industry. The book traces the foundations of Singapore's research story from the time of its independence in 1965 to the present day. Through interviews with the key players and research into the records, the establishment of the key institutes and the roles of a global cast of researchers, scientists and engineers in setting up the R&D infrastructure are outlined. The impact that the concerted efforts of the last 25 years to build up a credible and world-class research capability in Singapore is discussed, as are the tremendous challeng...

  15. A Simulation Model of Focus and Radial Servos in Compact Disc Players with Disc Surface Defects

    DEFF Research Database (Denmark)

    Odgaard, Peter Fogh; Stoustrup, Jakob; Andersen, Palle

    2004-01-01

    Compact Disc players have been on the market in more than two decades.As a consequence most of the control servo problems have been solved. A large remaining problem to solve is the handling of Compact Discs with severe surface defects like scratches and fingerprints. This paper introduces a method...... for making the design of controllers handling surface defects easier. A simulation model of Compact Disc players playing discs with surface defects is presented. The main novel element in the model is a model of the surface defects. That model is based on data from discs with surface defects. This model...

  16. Life Stories and Interculturality

    Directory of Open Access Journals (Sweden)

    Toldi Éva

    2014-12-01

    Full Text Available This article examines two short stories: Teréz Müller’s Igaz történet [A True Story] and József Bálint senior’s Imádkozzál és dolgozzál [Pray and Work]. The argument explores the way the texts reflect on shifts in power in the Hungarian region of Vojvodina, and the way power structures define the relationship between majority and minority in a society that undergoes constant and radical changes. Contemporary historical events of the twentieth century, changes, faultlines, traumatic life events and identity shifts emerge as the contexts for these narratives of the daily experiences of a Jewish merchant family and a farmer family respectively. Thus, the two texts analysed are representative works rooted in two fundamentally different social backgrounds. The discourse about the I is always also about the other; the construction of identity is already in itself a dialogic, intercultural act, which makes it an ideal topic for the exploration of the changes and shifts in one’s own and the other’s cultural identity. Translational processes of transmission are also required for the narration of traumatic experiences. Teréz Müller was the grandmother of the Serbian writer Aleksandar Tišma. Her book is not primarily a document of their relationship; however, it does throw light on diverse background events of the writer’s life and oeuvre. Comparing the experiences of identity in the autobiographical novel of Aleksandar Tišma and the recollections of his grandmother reveals geocultural characteristics of their intercultural life experiences.

  17. The Past, Present and Future of Cyber-Physical Systems: A Focus on Models

    Directory of Open Access Journals (Sweden)

    Edward A. Lee

    2015-02-01

    Full Text Available This paper is about better engineering of cyber-physical systems (CPSs through better models. Deterministic models have historically proven extremely useful and arguably form the kingpin of the industrial revolution and the digital and information technology revolutions. Key deterministic models that have proven successful include differential equations, synchronous digital logic and single-threaded imperative programs. Cyber-physical systems, however, combine these models in such a way that determinism is not preserved. Two projects show that deterministic CPS models with faithful physical realizations are possible and practical. The first project is PRET, which shows that the timing precision of synchronous digital logic can be practically made available at the software level of abstraction. The second project is Ptides (programming temporally-integrated distributed embedded systems, which shows that deterministic models for distributed cyber-physical systems have practical faithful realizations. These projects are existence proofs that deterministic CPS models are possible and practical.

  18. The Past, Present and Future of Cyber-Physical Systems: A Focus on Models

    Science.gov (United States)

    Lee, Edward A.

    2015-01-01

    This paper is about better engineering of cyber-physical systems (CPSs) through better models. Deterministic models have historically proven extremely useful and arguably form the kingpin of the industrial revolution and the digital and information technology revolutions. Key deterministic models that have proven successful include differential equations, synchronous digital logic and single-threaded imperative programs. Cyber-physical systems, however, combine these models in such a way that determinism is not preserved. Two projects show that deterministic CPS models with faithful physical realizations are possible and practical. The first project is PRET, which shows that the timing precision of synchronous digital logic can be practically made available at the software level of abstraction. The second project is Ptides (programming temporally-integrated distributed embedded systems), which shows that deterministic models for distributed cyber-physical systems have practical faithful realizations. These projects are existence proofs that deterministic CPS models are possible and practical. PMID:25730486

  19. The past, present and future of cyber-physical systems: a focus on models.

    Science.gov (United States)

    Lee, Edward A

    2015-02-26

    This paper is about better engineering of cyber-physical systems (CPSs) through better models. Deterministic models have historically proven extremely useful and arguably form the kingpin of the industrial revolution and the digital and information technology revolutions. Key deterministic models that have proven successful include differential equations, synchronous digital logic and single-threaded imperative programs. Cyber-physical systems, however, combine these models in such a way that determinism is not preserved. Two projects show that deterministic CPS models with faithful physical realizations are possible and practical. The first project is PRET, which shows that the timing precision of synchronous digital logic can be practically made available at the software level of abstraction. The second project is Ptides (programming temporally-integrated distributed embedded systems), which shows that deterministic models for distributed cyber-physical systems have practical faithful realizations. These projects are existence proofs that deterministic CPS models are possible and practical.

  20. Animal models of autism with a particular focus on the neural basis of changes in social behaviour: an update article.

    Science.gov (United States)

    Olexová, Lucia; Talarovičová, Alžbeta; Lewis-Evans, Ben; Borbélyová, Veronika; Kršková, Lucia

    2012-12-01

    Research on autism has been gaining more and more attention. However, its aetiology is not entirely known and several factors are thought to contribute to the development of this neurodevelopmental disorder. These potential contributing factors range from genetic heritability to environmental effects. A significant number of reviews have already been published on different aspects of autism research as well as focusing on using animal models to help expand current knowledge around its aetiology. However, the diverse range of symptoms and possible causes of autism have resulted in as equally wide variety of animal models of autism. In this update article we focus only on the animal models with neurobehavioural characteristics of social deficit related to autism and present an overview of the animal models with alterations in brain regions, neurotransmitters, or hormones that are involved in a decrease in sociability.

  1. A person-focused model of care for the twenty-first century: a system-of-systems perspective.

    Science.gov (United States)

    Greene, Robert A; Dasso, Edwin; Ho, Sam; Genaidy, Ash M

    2014-06-01

    The US health care system is challenged to provide high-quality care and is burdened with unsustainable expenditures, making it difficult for health care participants (patients, payers, providers, caregivers) to create value. This communication presents the theoretical foundation for a person-focused model of care that addresses a number of these challenges. The model integrates aspects of prior models of chronic care with new empiric findings and complex adaptive system (CAS) theory. The model emphasizes the relationship among all health care stakeholders. The health care delivery process is examined in terms of the role of each stakeholder and the value each adds to and receives from the process. The authors present pilot results illustrating the implications of CAS theory in regard to multi-morbidity, disease management programs, multi-morbid households, and person- and household-focused care. The model incorporates the physical, mental, and social dimensions of health, and operationalizes an individual patient's health as a CAS, identifying CASs for each of the other stakeholders as well. Health care can then be conceptualized as a system-of-systems with a person's health as its output. Deploying the model need not require major infrastructure investments or changes. It can be implemented by repurposing, aligning, and better integrating currently available interventions. The authors believe that the model creates not only survival value (health) but also purposeful value. The model offers a unifying focus for all participants in the health care delivery process, thereby constructing a health care system that is structurally person-focused and meaningful for all participants.

  2. Value-Focused Thinking Model to Evaluate SHM System Alternatives From Military end User Requirements Point of View

    OpenAIRE

    Klimaszewski Sławomir

    2016-01-01

    The article describes Value-Focused Thinking (VFT) model developed in order to evaluate various alternatives for implementation of Structural Health Monitoring (SHM) system on a military aircraft. Four SHM system alternatives are considered based on: visual inspection (current approach), piezoelectric (PZT) sensors, Fiber Bragg Grating (FBG) sensors and Comparative Vacuum Monitoring (CVM) sensors. A numerical example is shown to illustrate the model capability. Sensitivity analyses are perfor...

  3. Game story space of professional sports: Australian rules football

    Science.gov (United States)

    Kiley, Dilan Patrick; Reagan, Andrew J.; Mitchell, Lewis; Danforth, Christopher M.; Dodds, Peter Sheridan

    2016-05-01

    Sports are spontaneous generators of stories. Through skill and chance, the script of each game is dynamically written in real time by players acting out possible trajectories allowed by a sport's rules. By properly characterizing a given sport's ecology of "game stories," we are able to capture the sport's capacity for unfolding interesting narratives, in part by contrasting them with random walks. Here we explore the game story space afforded by a data set of 1310 Australian Football League (AFL) score lines. We find that AFL games exhibit a continuous spectrum of stories rather than distinct clusters. We show how coarse graining reveals identifiable motifs ranging from last-minute comeback wins to one-sided blowouts. Through an extensive comparison with biased random walks, we show that real AFL games deliver a broader array of motifs than null models, and we provide consequent insights into the narrative appeal of real games.

  4. The game story space of professional sports: Australian Rules Football

    CERN Document Server

    Kiley, D P; Mitchell, L; Danforth, C M; Dodds, P S

    2015-01-01

    Sports are spontaneous generators of stories. Through skill and chance, the script of each game is dynamically written in real time by players acting out possible trajectories allowed by a sport's rules. By properly characterizing a given sport's ecology of `game stories', we are able to capture the sport's capacity for unfolding interesting narratives, in part by contrasting them with random walks. Here, we explore the game story space afforded by a data set of 1,310 Australian Football League (AFL) score lines. We find that AFL games exhibit a continuous spectrum of stories and show how coarse-graining reveals identifiable motifs ranging from last minute comeback wins to one-sided blowouts. Through an extensive comparison with a random walk null model, we show that AFL games are superdiffusive and deliver a much broader array of motifs, and we provide consequent insights into the narrative appeal of real games.

  5. Decision story strategy: a practical approach for teaching decision making.

    Science.gov (United States)

    Smith, D L; Hamrick, M H; Anspaugh, D J

    1981-12-01

    Teachers are usually very enthusiastic in their evaluations of decision stories. Decision Story Strategies offer a change of pace, promote student involvement and stimulate creative thinking, problem solving and everpresent creative teaching-learning opportunities. The real-life problems presented within the structure of a decision story provide meaningful learning opportunities for students. Students begin to think in a broader perspective when considering other points of view and information sources. The Decision Story Strategy used with the Decision-Making Model provides a powerful tool for health educators to develop skills for making and evaluating decisions in an interesting and meaningful context. It may not be a panacea for all health educators, but is an effective strategy for the teacher concerned with developing independent decision makers. Most importantly, students are provided opportunities to solve their present problems as well as develop decision-making skills for the future.

  6. Game story space of professional sports: Australian rules football.

    Science.gov (United States)

    Kiley, Dilan Patrick; Reagan, Andrew J; Mitchell, Lewis; Danforth, Christopher M; Dodds, Peter Sheridan

    2016-05-01

    Sports are spontaneous generators of stories. Through skill and chance, the script of each game is dynamically written in real time by players acting out possible trajectories allowed by a sport's rules. By properly characterizing a given sport's ecology of "game stories," we are able to capture the sport's capacity for unfolding interesting narratives, in part by contrasting them with random walks. Here we explore the game story space afforded by a data set of 1310 Australian Football League (AFL) score lines. We find that AFL games exhibit a continuous spectrum of stories rather than distinct clusters. We show how coarse graining reveals identifiable motifs ranging from last-minute comeback wins to one-sided blowouts. Through an extensive comparison with biased random walks, we show that real AFL games deliver a broader array of motifs than null models, and we provide consequent insights into the narrative appeal of real games.

  7. A clinical reasoning model focused on clients' behaviour change with reference to physiotherapists: its multiphase development and validation.

    Science.gov (United States)

    Elvén, Maria; Hochwälder, Jacek; Dean, Elizabeth; Söderlund, Anne

    2015-05-01

    A biopsychosocial approach and behaviour change strategies have long been proposed to serve as a basis for addressing current multifaceted health problems. This emphasis has implications for clinical reasoning of health professionals. This study's aim was to develop and validate a conceptual model to guide physiotherapists' clinical reasoning focused on clients' behaviour change. Phase 1 consisted of the exploration of existing research and the research team's experiences and knowledge. Phases 2a and 2b consisted of validation and refinement of the model based on input from physiotherapy students in two focus groups (n = 5 per group) and from experts in behavioural medicine (n = 9). Phase 1 generated theoretical and evidence bases for the first version of a model. Phases 2a and 2b established the validity and value of the model. The final model described clinical reasoning focused on clients' behaviour change as a cognitive, reflective, collaborative and iterative process with multiple interrelated levels that included input from the client and physiotherapist, a functional behavioural analysis of the activity-related target behaviour and the selection of strategies for behaviour change. This unique model, theory- and evidence-informed, has been developed to help physiotherapists to apply clinical reasoning systematically in the process of behaviour change with their clients.

  8. Introducing Interactive Technology--"Toy Story 3"

    Science.gov (United States)

    Nikirk, Martin

    2011-01-01

    "To infinity and beyond!" is the catchphrase of Buzz Lightyear, Universe Protection Unit space ranger, a character in the Disney/Pixar "Toy Story" franchise. The three films in the franchise--"Toy Story," 1993; "Toy Story 2," 1999; and "Toy Story 3," 2010--incorporate an innovative blend of many different genres, having spun off video games and…

  9. Stories of Experience and Narrative Inquiry.

    Science.gov (United States)

    Connelly, F. Michael; Clandinin, D. Jean

    1990-01-01

    Surveys forms of narrative inquiry in educational studies. Outlines certain criteria, methods, and writing forms. Describes them in terms of beginning the story, living the story, and selecting stories to construct and reconstruct narrative plots. Describes two-part research agenda for curriculum and studies flowing from stories of experience and…

  10. Scripting History: The Genre of Desegregation Stories

    Science.gov (United States)

    Lesley, Naomi

    2015-01-01

    This article argues that desegregation stories form a subset of the school story genre. In drawing upon school story traditions, desegregation stories offer some unexpected and politically contentious solutions to the problems of segregated schooling, including queer friendships and critiques of classroom pedagogy. Nevertheless, the resolution of…

  11. Analysis of The Story of An Hour

    Institute of Scientific and Technical Information of China (English)

    曹玉琴

    2014-01-01

    By reading the short story The Story of An Hour written by Kate Chopin, we tried to probe the story better by analyz-ing five characters, plots of the story and rhetorical devices, such as irony and symbolism. With originality and profound mean-ings, the novel about the small theme of family life had a wide variety of social significance.

  12. Automated Reasoning Across Tactical Stories to Derive Lessons Learned

    Directory of Open Access Journals (Sweden)

    J. Wesley Regian

    2008-06-01

    Full Text Available The Military Analogical Reasoning System (MARS is a performance support system and decision aid for commanders in Tactical Operations Centers. MARS enhances and supports the innate human ability for using stories to reason about tactical goals, plans, situations, and outcomes. The system operates by comparing many instances of stored tactical stories, determining which have analogous situations and lessons learned, and then returning a description of the lessons learned. The description of the lessons learned is at a level of abstraction that can be generalized to an appropriate range of tactical situations. The machine-understandable story representation is based on a military operations data model and associated tactical situation ontology. Thus each story can be thought of, and reasoned about, as an instance of an unfolding tactical situation. The analogical reasoning algorithm is based on Gentner's Structure Mapping Theory. Consider the following two stories. In the first, a U.S. platoon in Viet Nam diverts around a minefield and subsequently comes under ambush from a large hill overlooking their new position. In the second, a U.S. task force in Iraq diverts around a biochemical hazard and subsequently comes under ambush from the roof of an abandoned building. MARS recognizes these stories as analogical, and derives the following abstraction: When enemy-placed obstacles force us into an unplanned route, beware of ambush from elevation or concealment. In this paper we describe the MARS interface, military operations data model, tactical situation ontology, and analogical reasoning algorithm.

  13. Co-Story-ing: Collaborative Story Writing with Children Who Fear

    Science.gov (United States)

    Pehrsson, Dale-Elizabeth

    2007-01-01

    This article offers a guide for using collaborative story writing (co-story-ing), an assessment technique as well as a therapeutic intervention for children who demonstrate fears, extreme shyness and difficulty in establishing relationships. Co-story-ing draws from Gardner's Mutual Story Telling Technique. Co-story-ing guides clients as they…

  14. Forces from highly focused laser beams: modeling, measurement and application to refractive index measurements

    CERN Document Server

    Knoener, G; Nieminen, T A; Heckenberg, N R; Rubinsztein-Dunlop, H

    2007-01-01

    The optical forces in optical tweezers can be robustly modeled over a broad range of parameters using generalsed Lorenz-Mie theory. We describe the procedure, and show how the combination of experimental measurement of properties of the trap coupled with computational modeling, can allow unknown parameters of the particle - in this case, the refractive index - to be determined.

  15. The Effect of Flipped Model of Instruction on EFL Learners' Reading Comprehension: Learners' Attitudes in Focus

    Science.gov (United States)

    Karimi, Mehrnoosh; Hamzavi, Raouf

    2017-01-01

    The present study aimed at investigating the effect of flipped model of instruction on EFL learners' reading comprehension ability. Moreover, this study aimed at identifying EFL students' attitudes toward flipped model of instruction. To this end, 60 EFL learners studying at an accredited private language institute in Isfahan were first…

  16. Detective Stories from Sherlock Holmes to Whitechapel

    Directory of Open Access Journals (Sweden)

    Feryal Çubukcu

    2015-12-01

    Full Text Available Detective Stories from Sherlock Holmes to Whitechapel Abstract The Victorian period in England was one of the most influential and important epochs in history. During Queen Victoria’s reign, England was arguably the most powerful nation in the world, setting standards for social, economic and industrial development. Among the rules of Victorian society were stringent codes pertaining to what was acceptable for men and women. Men were expected to hold decent jobs, marry respectable women, and create the next generation of proper British citizens. Women were raised to marry, breed virtuous English children, and live quietly in the confines of the household. As Elaine Showalter (1987 says Victorian households had different spheres for men and women. There were certain behavioral norms for men and women that were standard practice for asserting one’s proper gender codes. In his 1995 book Victorian Masculinities, Herbert Sussman identifies, within Victorian men’s writing, a method of constructing masculinity that opposes the dominant English model of manliness based on bourgeois domestic matrimony. During the first half of the Victorian period, normative masculinity required a man to master his psychic energy by establishing a bourgeois domestic identity founded on matrimony. However, this concept translates into the bachelordom plot, wherein male desire finds an appropriate outlet in a sidekick rather than a wife, thus, under the terms of popular middle-class belief, permanently affirming masculinity. When we come to 2010s a bestseller Whitechapel hinges on the same lone detective trying to pursue the killers and criminals. The purpose of this paper is to probe and grapple with the similarities and dissimilarities the detective genre from Sherlock Holmes to Whitechapel by focusing on the detective himself, the crime types, criminals- their motives and ethnic origins-, masculinity, and male-male bonding.

  17. From Image Processing to Classification: 1. Modelling Disturbances of Isoelectric Focusing Patterns

    DEFF Research Database (Denmark)

    Jensen, Karsten; Søndergaard, I.; Skovgaard, I. M.

    1995-01-01

    In order to optimize the conditions for evaluation of isoelectric focusing (IEF) patterns by digital image processing, the sources of error in determination of the pi values were analyzed together with the influence of a varying background. The effects of band distortions, in the spectra...... of the individual lanes, were examined. In order to minimize the effect of these distortions, optimal conditions for handling IEF patterns by digital image processing were elucidated. The systematic part of the global deformation on the gels was investigated and an algorithm was developed by which it was possible...

  18. Experimental Modeling of the Electron Beam Focusing Regimesin the Axially-Symmetric Systems

    Directory of Open Access Journals (Sweden)

    I.V. Barsuk

    2014-04-01

    Full Text Available The paper describes the results of the experimental research of the volt-ampere characteristics of the three-electrode electron gun. Such systems are widely used in the electron-ray devices meant for getting visible image on the screen, and in microwave devices, such as TWT, BWT, as well. On the basis of the experimental results practical recommendations of how to choose the optimal voltage regimes on the focusing electrodes were made, which allows to form paraxial axially-symmetric beams with the diameter in crossover about 0.05-0.5 mm and beam current up to 30 mA.

  19. SAGA: A DSL for Story Management

    Directory of Open Access Journals (Sweden)

    Lucas Beyak

    2011-09-01

    Full Text Available Video game development is currently a very labour-intensive endeavour. Furthermore it involves multi-disciplinary teams of artistic content creators and programmers, whose typical working patterns are not easily meshed. SAGA is our first effort at augmenting the productivity of such teams. Already convinced of the benefits of DSLs, we set out to analyze the domains present in games in order to find out which would be most amenable to the DSL approach. Based on previous work, we thus sought those sub-parts that already had a partially established vocabulary and at the same time could be well modeled using classical computer science structures. We settled on the 'story' aspect of video games as the best candidate domain, which can be modeled using state transition systems. As we are working with a specific company as the ultimate customer for this work, an additional requirement was that our DSL should produce code that can be used within a pre-existing framework. We developed a full system (SAGA comprised of a parser for a human-friendly language for 'story events', an internal representation of design patterns for implementing object-oriented state-transitions systems, an instantiator for these patterns for a specific 'story', and three renderers (for C++, C# and Java for the instantiated abstract code.

  20. Situating math word problems: the story matters.

    Science.gov (United States)

    Mattarella-Micke, Andrew; Beilock, Sian L

    2010-02-01

    In two experiments, we explored how the situation model of a math story problem impacts math problem performance. Participants completed multiplication story problems in which a set of objects was associated with or dissociated from a protagonist, making them more or less accessible in memory during answer retrieval. On the basis of previous findings that the sum of two numbers interferes with retrieval of their product, the number of objects in the math problem was either highly interfering ("9" for 4 x 5) or less interfering ("8" for 4 x 5) for multiplication retrieval in the problem. Participants made more errors in problem solving when highly interfering numerical content was associated with the protagonist and, thus, foregrounded. Moreover, the lower one's working memory, the bigger this effect. In sum, small changes in the situation model of a math story problem can harm performance. These changes shift the balance of factors that influence math performance away from math knowledge and toward individual differences in general cognitive capacity.

  1. USING THE SOUTH AFRICAN EXCELLENCE MODEL TO FOCUS IMPROVEMENT STRATEGIES IN SOUTH AFRICA.

    Directory of Open Access Journals (Sweden)

    Bruce R Smit

    2012-01-01

    Full Text Available

    ENGLISH ABSTRACT: South African companies wish to join the world class family. As the Malcolm Baldrige Quality Award in the USA and the European Quality Award in Europe have been effected, the South African Quality Institute (SAQI pioneered and developed a National Quality Award together with leading South African companies. The South African Award model is a full hybrid of the Malcolm Baldrige and European Foundation Quality models. The awards process is now managed by the South African Excellence Foundation. This model enables companies to assess their excellence levels and use benchmarks towards improved quality, service and costs. The model has been ratified by the administrators of both of the aforementioned awards. The criteria in the award lend themselves to measurement by self assessment. This paper explains the model and its application as a foundation to strategic planning.

    AFRIKAANSE OPSOMMING: Maatskapye in Suid Afrika moet op die wereldmark kan presteer. Amerika het die Malcolm Baldrige Kwaliteitstoekenning en Europa die Europese Kwaliteitstoekenning.vir uitmuntende prestasie in die besigheidswereld daargestel. Die Suid Afrikaanse Kwaliteitsinstituut (SAQI het in 1997 'n Suid Afrikaanse eweknie ontwikkel. Die Suid Afrikaanse Kwaliteitstoekenning is deur die administrateurs van eersgenoemde pryse aanvaar. Die lokale Kwaliteitstoekennings word tans deur die Suid Afrikaanse Uitmuntentheidfondasie geadministreer. Die Kwaliteitstoekenning model kan gebruik word am self-meting toe te pas met die doel om besigheids prestasie te verbeter. Hierdie geskrif stel die Suid Afrikaanse model daar stel en verduidelik hoe dit vir strategiese beplanning toegepas kan word.

  2. Applications of animal models of infectious arthritis in drug discovery: a focus on alphaviral disease.

    Science.gov (United States)

    Herrero, Lara; Nelson, Michelle; Bettadapura, Jayaram; Gahan, Michelle E; Mahalingam, Suresh

    2011-06-01

    Animal models, which mimic human disease, are invaluable tools for understanding the mechanisms of disease pathogenesis and development of treatment strategies. In particular, animal models play important roles in the area of infectious arthritis. Alphaviruses, including Ross River virus (RRV), o'nyong-nyong virus, chikungunya virus (CHIKV), mayaro virus, Semliki Forest virus and sindbis virus, are globally distributed and cause transient illness characterized by fever, rash, myalgia, arthralgia and arthritis in humans. Severe forms of the disease result in chronic incapacitating arthralgia and arthritis. The mechanisms of how these viruses cause musculoskeletal disease are ill defined. In recent years, the use of a mouse model for RRV-induced disease has assisted in unraveling the pathobiology of infection and in discovering novel drugs to ameliorate disease. RRV as an infection model has the potential to provide key insights into such disease processes, particularly as many viruses, other than alphaviruses, are known to cause infectious arthritides. The emergence and outbreak of CHIKV in many parts of the world has necessitated the need to develop animal models of CHIKV disease. The development of non-human primate models of CHIKV disease has given insights into viral tropism and disease pathogenesis and facilitated the development of new treatment strategies. This review highlights the application of animal models of alphaviral diseases in the fundamental understanding of the mechanisms that contribute to disease and for defining the role that the immune response may have on disease pathogenesis, with the view of providing the foundation for new treatments.

  3. Novel use of noninvasive high-intensity focused ultrasonography for intercostal nerve neurolysis in a swine model.

    Science.gov (United States)

    Gulati, Amitabh; Loh, Jeffrey; Gutta, Narendra B; Ezell, Paula C; Monette, Sébastien; Erinjeri, Joseph P; Maybody, Majid; Solomon, Stephen

    2014-01-01

    High-intensity focused ultrasound (HIFU) is a noninvasive thermal ablation technique. High-intensity focused ultrasound has been used in small-animal models to lesion neural tissue selectively. This study aimed to evaluate the efficacy of HIFU in a large-animal model for ablation of nerves similar in size to human nerves. Twelve acute magnetic resonance-guided HIFU ablation lesions were created in intercostal nerves in a swine model. In a second pig, as a control, 4 radiofrequency ablation and 4 alcohol lesions were performed on intercostal nerves under ultrasound guidance. Preprocedural and postprocedural magnetic resonance imaging was then performed to evaluate radiologically the lesion size created by HIFU. Animals were euthanized 1 hour postprocedure, and necropsy was performed to collect tissue samples for histopathologic analysis. On gross and histological examination of the intercostal nerve, acute HIFU nerve lesions showed evidence of well-demarcated, acute, focally extensive thermal necrosis. Four intercostal nerves ablated with HIFU were sent for histopathologic analysis, with 2 of 4 lesions showing pathologic damage to the intercostal nerve. Similar results were shown with radiofrequency ablation technique, whereas the intercostal nerves appeared histologically intact with alcohol ablation. High-intensity focused ultrasound may be used as a noninvasive neurolytic technique in swine. High-intensity focused ultrasound may have potential as a neuroablation technique for patients with chronic and cancer pain.

  4. Embodiment during Reading: Simulating a Story Character's Linguistic Actions

    Science.gov (United States)

    Gunraj, Danielle N.; Drumm-Hewitt, April M.; Klin, Celia M.

    2014-01-01

    According to theories of embodied cognition, a critical element in language comprehension is the formation of sensorimotor simulations of the actions and events described in a text. Although much of the embodied cognition research has focused on simulations of motor actions, we ask whether readers form simulations of story characters' linguistic…

  5. Story Crafting: Strategies for Facilitating Narrative Career Counselling

    Science.gov (United States)

    McMahon, Mary; Watson, Mark

    2012-01-01

    Narrative career counselling is a growing force in career guidance and counselling that offers a direction for the field to respond to the needs of increasingly diverse client groups. In this article, we review established and emerging approaches to narrative career counselling, then focus on the emerging story telling approach. We offer examples…

  6. Las Rocas Nos Cuentan (Rocks Tell Their Stories)

    Science.gov (United States)

    Llerandi-Roman, Pablo A.

    2012-01-01

    Many Earth science lessons today still focus on memorizing the names of rocks and minerals. This led the author to develop a lesson that reveals the fascinating stories told by rocks through the study of their physical properties. He first designed the lesson for Puerto Rican teachers, hence its Spanish title: "Las Rocas Nos Cuentan Su Historia."…

  7. Magical Stories: Blending Virtual Reality and Artificial Intelligence.

    Science.gov (United States)

    McLellan, Hilary

    Artificial intelligence (AI) techniques and virtual reality (VR) make possible powerful interactive stories, and this paper focuses on examples of virtual characters in three dimensional (3-D) worlds. Waldern, a virtual reality game designer, has theorized about and implemented software design of virtual teammates and opponents that incorporate AI…

  8. Las Rocas Nos Cuentan (Rocks Tell Their Stories)

    Science.gov (United States)

    Llerandi-Roman, Pablo A.

    2012-01-01

    Many Earth science lessons today still focus on memorizing the names of rocks and minerals. This led the author to develop a lesson that reveals the fascinating stories told by rocks through the study of their physical properties. He first designed the lesson for Puerto Rican teachers, hence its Spanish title: "Las Rocas Nos Cuentan Su Historia."…

  9. Vaccination and infectious diseases: a never ending story

    Directory of Open Access Journals (Sweden)

    Giuseppe La Torre

    2012-03-01

    Full Text Available

    Extract: The relationship between vaccine and infectious diseases can be easily considered a never ending story. In the 3rd issue of 2009 of this journal, thematic papers were related to vaccination policies and practice, with a particular focus on vaccine and vaccination evalu- ation and assessment....

  10. Story Crafting: Strategies for Facilitating Narrative Career Counselling

    Science.gov (United States)

    McMahon, Mary; Watson, Mark

    2012-01-01

    Narrative career counselling is a growing force in career guidance and counselling that offers a direction for the field to respond to the needs of increasingly diverse client groups. In this article, we review established and emerging approaches to narrative career counselling, then focus on the emerging story telling approach. We offer examples…

  11. A Painting Tells Its Story

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Separated parts of an ancient Chinese painting to be displayed together Chinese Premier Wen Jiabao told a story about a famous Chinese painting Dwelling in the Fuchun Mountains at a press conference after the Third Session of the

  12. Transmedia storytelling on travel stories

    Directory of Open Access Journals (Sweden)

    Adolfo Baltar Moreno

    2016-01-01

    Full Text Available Travel stories form part of a great tradition inside Western Culture which has served historically to describe, to understand and to imagine other cul - tures and communities, far or near, being constituted into a real narra - tive genre. This type of story has been and is a reflection of the perception of the world based on the imaginary worlds created by the travelling narrators. How do modern authors of travel stories take advantage of the opportunities offered by transmedia storytelling? The present article explores the potential of these types of stories as a privileged object of study for transmedia storytelling studies, from the analysis of a sample of 80 narrative productions based on experiences of travel and presented in diverse editions of the Festival Le Grand Bivouac (France. It also shows the existence of a new contemporary trend inside this narrative form that transcends its literary nature.

  13. Storying Our Claims, Claiming Our Stories: Becoming through Narrative in the Social-Justice Focused Classroom

    Science.gov (United States)

    Kantor, Julia Churchill

    2013-01-01

    The following project uses both narrative and feminist poststructural lenses to consider how narratives operated in one undergraduate social foundations of education class purposefully designed around issues of social justice. These theoretical frameworks were useful in exploring the ways students and myself, the course instructor, were variously…

  14. Design and Manufacture of a Hybrid Final Focus Quadrupole Model for CLIC

    CERN Document Server

    Modena, Michele; Vorozhtsov, Alexey

    2012-01-01

    A tunable hybrid quadrupole magnet design has been proposed for the final focus in the Compact Linear Collider (CLIC) that is currently under study. The proposed design is a combination of an iron dominated electromagnetic quadrupole with a bore diameter of 8.25 mm with permanent magnet blocks placed between the poles made of soft magnetic CoFe alloy "Permendur". The possibility of using Sm2Co17 and Nd2Fe14B as material for the permanent magnet blocks has been investigated. It is shown that a very high field gradient of 530 T/m (Sm2Co17) and 590 T/m (Nd2Fe14B) can be achieved.

  15. A true case story

    Directory of Open Access Journals (Sweden)

    Hanne Bjørg Walker

    2012-08-01

    Full Text Available Autism is not generally recognized as a condition which can be bio-medically influenced. As of today, there are no biomarkers for autism that are recognized by traditional medicine. Treating autism medically is a difficult and hopeless task according to official guidelines (even though it is seldom written in official documents. Parents of many children who have or had an ASD diagnosis have witnessed significant improvements in their children after dietary interventions as well as after interventions with vitamins, minerals and biogene substances which can be bought over the counter. The parents of individual children are their best observers. With a high degree of certainty, they are able to see which substances improve or weaken their children. Their observations are usually accurate, but their rationale for why is often wrong. Observations from parents can often be of greater importance for the child than advice from so called experts. This is a true story about a girl whose parents lost contact with her when she was only 6 months old. In her first 14 days she lost her ability to roll over, to babble and make sounds. She did not look at her parents any more – just stared up at the roof. At 9 months she did not respond to words such as, ‘look at mommy’. Through the parents own experiences with her older siblings and 4 months of frantic searching for a diet that would agree with the child, she made a remarkable journey from 10 months of age to 18 months. There is one thing worth mentioning – she refused to eat solid food throughout this time. The story does not end there. Today she is 12 years old and has had to be regulated with diet and biogene substances every day since she was 4 years old. During the last 5 months she has shown more stability and can even go a day or two without biogene substances as long as she keeps to her dietary plan. If you had just met her and spent a day with her, you would never know.

  16. Development and evaluation of the herd dynamic milk model with focus on the individual cow component.

    Science.gov (United States)

    Ruelle, E; Delaby, L; Wallace, M; Shalloo, L

    2016-12-01

    The herd dynamic milk (HDM) model is a dynamic model capable of simulating the performance of individual dairy animals (from birth to death), with a daily time step. Within this study, the HDM model is described and evaluated in relation to milk production, body condition score (BCS) and BCS change throughout lactation by comparing model simulations against data from published experimental studies. The model's response to variation in genetic potential, herbage allowance and concentrate supplementation was tested in a sensitivity analysis. Data from experiments in Ireland and France over a 3-year period (2009-11) were used to complete the evaluation. The aim of the Irish experiment was to determine the impact of different stocking rates (SRs) (SR1: 3.28 cow/ha, SR2: 2.51 cow/ha) on key physical, biological and economic performance. The aim of the French experiment was to evaluate over a prolonged time period, the ability of two breeds of dairy cows (Holstein and Normande) to produce and to reproduce under two feeding strategies (high level and low level) in the context of compact calving. The model evaluation was conducted at the herd level with separate evaluations for the primiparous and multiparous cows. The evaluation included the two extreme SRs for the Irish experiment, and an evaluation at the overall herd and individual animal level for the different breeds and feeding levels for the French data. The comparison of simulation and experimental data for all scenarios resulted in a relative prediction error, which was consistently model responded in a realistic fashion to variation in genetic potential for milk production, herbage allowance and concentrate supplementation.

  17. Use of animal models for space flight physiology studies, with special focus on the immune system

    Science.gov (United States)

    Sonnenfeld, Gerald

    2005-01-01

    Animal models have been used to study the effects of space flight on physiological systems. The animal models have been used because of the limited availability of human subjects for studies to be carried out in space as well as because of the need to carry out experiments requiring samples and experimental conditions that cannot be performed using humans. Experiments have been carried out in space using a variety of species, and included developmental biology studies. These species included rats, mice, non-human primates, fish, invertebrates, amphibians and insects. The species were chosen because they best fit the experimental conditions required for the experiments. Experiments with animals have also been carried out utilizing ground-based models that simulate some of the effects of exposure to space flight conditions. Most of the animal studies have generated results that parallel the effects of space flight on human physiological systems. Systems studied have included the neurovestibular system, the musculoskeletal system, the immune system, the neurological system, the hematological system, and the cardiovascular system. Hindlimb unloading, a ground-based model of some of the effects of space flight on the immune system, has been used to study the effects of space flight conditions on physiological parameters. For the immune system, exposure to hindlimb unloading has been shown to results in alterations of the immune system similar to those observed after space flight. This has permitted the development of experiments that demonstrated compromised resistance to infection in rodents maintained in the hindlimb unloading model as well as the beginning of studies to develop countermeasures to ameliorate or prevent such occurrences. Although there are limitations to the use of animal models for the effects of space flight on physiological systems, the animal models should prove very valuable in designing countermeasures for exploration class missions of the future.

  18. Development and modeling of a stereo vision focusing system for a field programmable gate array robot

    Science.gov (United States)

    Tickle, Andrew J.; Buckle, James; Grindley, Josef E.; Smith, Jeremy S.

    2010-10-01

    Stereo vision is a situation where an imaging system has two or more cameras in order to make it more robust by mimicking the human vision system. By using two inputs, knowledge of their own relative geometry can be exploited to derive depth information from the two views they receive. 3D co-ordinates of an object in an observed scene can be computed from the intersection of the two sets of rays. Presented here is the development of a stereo vision system to focus on an object at the centre of a baseline between two cameras at varying distances. This has been developed primarily for use on a Field Programmable Gate Array (FPGA) but an adaptation of this developed methodology is also presented for use with a PUMA 560 Robotic Manipulator with a single camera attachment. The two main vision systems considered here are a fixed baseline with an object moving at varying distances from this baseline, and a system with a fixed distance and a varying baseline. These two differing situations provide enough data so that the co-efficient variables that determine the system operation can be calibrated automatically with only the baseline value needing to be entered, the system performs all the required calculations for the user for use with a baseline of any distance. The limits of system with regards to the focusing accuracy obtained are also presented along with how the PUMA 560 controls its joints for the stereo vision and how it moves from one position to another to attend stereo vision compared to the two camera system for the FPGA. The benefits of such a system for range finding in mobile robotics are discussed and how this approach is more advantageous when compared against laser range finders or echolocation using ultrasonics.

  19. Reduced Order Modeling of Bubble Cloud Dynamics in a Focused Ultrasound Field

    Science.gov (United States)

    Maeda, Kazuki; Colonius, Tim

    2016-11-01

    In order to characterize the cloud cavitation in burst wave lithotripsy, reduced order modeling of the dynamics of a spherical bubble cloud of a radius O (1) mm interacting with traveling ultrasound waves of an amplitude O(1) MPa in water is presented. Bubbles are treated as spherical, radially oscillating cavities dispersed in continuous liquid phase. The volume of Lagrangian point bubbles is mapped with a regularization kernel as void fraction onto three-dimensional Cartesian grids that define the Eulerian liquid phase. The flow field is solved using a WENO-based compressible flow solver. The initial size and number density of the bubbles are critical for their coherent dynamics in the cloud, yet three-dimensional simulations of clouds with various parameters are computationally demanding. For further reduced-order modeling, a new kernel is introduce into the model to regularize bubbles onto two-dimensional, axisymmetric grids. The evolution of the void fraction and the maximum pressure in the cloud simulated using the model agree with results of three-dimensional simulations, while the reduction in computational cost is a factor of O (100) . Finally, the model is applied to a parametric study of the coherent dynamics of bubbles.

  20. Survey review of models for use in market penetration analysis: utility sector focus

    Energy Technology Data Exchange (ETDEWEB)

    Groncki, P.J.; Kydes, A.S.; Lamontagne, J.; Marcuse, W.; Vinjamuri, G.

    1980-11-01

    The ultimate benefits of federal expenditures in research and development for new technologies are dependent upon the degree of acceptance of these technologies. Market penetration considerations are central to the problem of quantifying the potential benefits. These benefits are inputs to the selection process of projects competing for finite R and D funds. Market penetration is the gradual acceptance of a new commodity or technology. The Office of Coal utilization is concerned with the specialized area of market penetration of new electric power generation technologies for both replacement and new capacity. The common measure of market penetration is the fraction of the market serviced by the challenging technology for each time point considered. The methodologies for estimating market penetration are divided into three generic classes: integrated energy/economy modeling systems, utility capacity expansion models, and technology substitution models. In general, the integrated energy/economy modeling systems have three advantages: they provide internally consistent macro, energy-economy scenarios, they account for the effect of prices on demand by fuel form, and they explicitly capture the effects of population growth and the level and structure of economic activity on energy demand. A variety of deficiencies appear in most energy-economy systems models. All of the methodologies may be applied at some level to questions of market penetration of new technologies in the utility sector; choice of methods for a particular analysis must be conditioned by the scope of the analysis, data availability, and the relative cost of alternative analysis.

  1. Representing spatial and temporal complexity in ecohydrological models: a meta-analysis focusing on groundwater - surface water interactions

    Science.gov (United States)

    McDonald, Karlie; Mika, Sarah; Kolbe, Tamara; Abbott, Ben; Ciocca, Francesco; Marruedo, Amaia; Hannah, David; Schmidt, Christian; Fleckenstein, Jan; Karuse, Stefan

    2016-04-01

    Sub-surface hydrologic processes are highly dynamic, varying spatially and temporally with strong links to the geomorphology and hydrogeologic properties of an area. This spatial and temporal complexity is a critical regulator of biogeochemical and ecological processes within the interface groundwater - surface water (GW-SW) ecohydrological interface and adjacent ecosystems. Many GW-SW models have attempted to capture this spatial and temporal complexity with varying degrees of success. The incorporation of spatial and temporal complexity within GW-SW model configuration is important to investigate interactions with transient storage and subsurface geology, infiltration and recharge, and mass balance of exchange fluxes at the GW-SW ecohydrological interface. Additionally, characterising spatial and temporal complexity in GW-SW models is essential to derive predictions using realistic environmental conditions. In this paper we conduct a systematic Web of Science meta-analysis of conceptual, hydrodynamic, and reactive and heat transport models of the GW-SW ecohydrological interface since 2004 to explore how these models handled spatial and temporal complexity. The freshwater - groundwater ecohydrological interface was the most commonly represented in publications between 2004 and 2014 with 91% of papers followed by marine 6% and estuarine systems with 3% of papers. Of the GW-SW models published since 2004, the 52% have focused on hydrodynamic processes and heat and reactive transport). Within the hydrodynamic subset, 25% of models focused on a vertical depth of limitations of incorporating spatial and temporal variability into GW-SW models are identified as the inclusion of woody debris, carbon sources, subsurface geological structures and bioclogging into model parameterization. The technological limitations influence the types of models applied, such as hydrostatic coupled models and fully intrinsic saturated and unsaturated models, and the assumptions or

  2. Validation of the dynamic wake meander model with focus on tower loads

    DEFF Research Database (Denmark)

    Larsen, Torben J.; Larsen, Gunner Chr.; Pedersen, Mads Mølgaard

    2017-01-01

    of wind speeds. In general, tower loads in wake conditions are very challenging to predict correctly in simulations. The Nysted project offers an improved insight to this field as six wind turbines located in the Nysted II wind farm have been instrumented to measure tower top and tower bottom moments. All...... a period extending over a time span of more than 3 years. Based on the recorded data basic mechanisms driving the increased loading experienced by wind turbines operating in offshore wind farm conditions have been identified, characterized and modeled. The modeling is based on the Dynamic Wake Meandering...... (DWM) approach in combination with the state-of-the-art aeroelastic model HAWC2, and has previously as well as in this study shown good agreement with the measurements. The conclusions from the study have several parts. In general the tower bending and yaw loads show a good agreement between...

  3. Computational fluid dynamics modelling of biomass fast pyrolysis in fluidised bed reactors, focusing different kinetic schemes.

    Science.gov (United States)

    Ranganathan, Panneerselvam; Gu, Sai

    2016-08-01

    The present work concerns with CFD modelling of biomass fast pyrolysis in a fluidised bed reactor. Initially, a study was conducted to understand the hydrodynamics of the fluidised bed reactor by investigating the particle density and size, and gas velocity effect. With the basic understanding of hydrodynamics, the study was further extended to investigate the different kinetic schemes for biomass fast pyrolysis process. The Eulerian-Eulerian approach was used to model the complex multiphase flows in the reactor. The yield of the products from the simulation was compared with the experimental data. A good comparison was obtained between the literature results and CFD simulation. It is also found that CFD prediction with the advanced kinetic scheme is better when compared to other schemes. With the confidence obtained from the CFD models, a parametric study was carried out to study the effect of biomass particle type and size and temperature on the yield of the products.

  4. Immediate survival focus: synthesizing life history theory and dual process models to explain substance use.

    Science.gov (United States)

    Richardson, George B; Hardesty, Patrick

    2012-01-01

    Researchers have recently applied evolutionary life history theory to the understanding of behaviors often conceived of as prosocial or antisocial. In addition, researchers have applied cognitive science to the understanding of substance use and used dual process models, where explicit cognitive processes are modeled as relatively distinct from implicit cognitive processes, to explain and predict substance use behaviors. In this paper we synthesized these two theoretical perspectives to produce an adaptive and cognitive framework for explaining substance use. We contend that this framework provides new insights into the nature of substance use that may be valuable for both clinicians and researchers.

  5. Immediate Survival Focus: Synthesizing Life History Theory and Dual Process Models to Explain Substance Use

    Directory of Open Access Journals (Sweden)

    George B. Richardson

    2012-10-01

    Full Text Available Researchers have recently applied evolutionary life history theory to the understanding of behaviors often conceived of as prosocial or antisocial. In addition, researchers have applied cognitive science to the understanding of substance use and used dual process models, where explicit cognitive processes are modeled as relatively distinct from implicit cognitive processes, to explain and predict substance use behaviors. In this paper we synthesized these two theoretical perspectives to produce an adaptive and cognitive framework for explaining substance use. We contend that this framework provides new insights into the nature of substance use that may be valuable for both clinicians and researchers.

  6. Enhancement of speech signals - with a focus on voiced speech models

    DEFF Research Database (Denmark)

    Nørholm, Sidsel Marie

    This thesis deals with speech enhancement, i.e., noise reduction in speech signals. This has applications in, e.g., hearing aids and teleconference systems. We consider a signal-driven approach to speech enhancement where a model of the speech is assumed and filters are generated based on this mo......This thesis deals with speech enhancement, i.e., noise reduction in speech signals. This has applications in, e.g., hearing aids and teleconference systems. We consider a signal-driven approach to speech enhancement where a model of the speech is assumed and filters are generated based...

  7. Creation Stories: Myths about the Origin of Money

    OpenAIRE

    Desan, Christine

    2013-01-01

    A myth about the origins of money has long organized modern approaches to the medium. According to that creation story, money is the natural product of human exchange. It can be analogized to a commodity like silver that comes to hand out of the decentralized activity of trading or a convention like language that arises out of a consensus about the value of an item. But if we consider clues about money’s origins and extrapolate from its continuing practice, another story comes into focus. It ...

  8. A computational model of focused attention meditation and its transfer to a sustained attention task

    NARCIS (Netherlands)

    van Vugt, Marieke; Moye, Amir Sep; van Vugt, Marieke K; Banks, Adrian P; Kennedy, William G

    2017-01-01

    Although meditation and mindfulness practices are widely discussed and studied more and more in the scientific literature, there is little theory about the cognitive mechanisms that comprise it. Here we begin to develop such a theory by creating a computational cognitive model of a particular type o

  9. A computational model of focused attention meditation and its transfer to a sustained attention task

    NARCIS (Netherlands)

    Moye, Amir Sep; van Vugt, Marieke; van Vugt, Marieke K; Banks, Adrian P; Kennedy, William G

    2017-01-01

    Although meditation and mindfulness practices are widely discussed and studied more and more in the scientific literature, there is little theory about the cognitive mechanisms that comprise it. Here we begin to develop such a theory by creating a computational cognitive model of a particular type

  10. Triple Diagonal modeling: A mechanism to focus productivity improvement for business success

    Energy Technology Data Exchange (ETDEWEB)

    Levine, L.O. [Pacific Northwest Lab., Richland, WA (United States); Villareal, L.D. [Army Depot, Corpus Christi, TX (United States)

    1993-09-01

    Triple Diagonal (M) modeling is a technique to help quickly diagnose an organization`s existing production system and to identify significant improvement opportunities in executing, controlling, and planning operations. TD modeling is derived from ICAM Definition Language (IDEF 0)-also known as Structured Analysis and Design Technique. It has been used successfully at several Department of Defense remanufacturing facilities trying to accomplish significant production system modernization. TD has several advantages over other modeling techniques. First, it quickly does ``As-ls`` analysis and then moves on to identify improvements. Second, creating one large diagram makes it easier to share the TD model throughout an organization, rather than the many linked 8 1/2 {times} 11`` drawings used in traditional decomposition approaches. Third, it acts as a communication mechanism to share understanding about improvement opportunities that may cross existing functional/organizational boundaries. Finally, TD acts as a vehicle to build a consensus on a prioritized list of improvement efforts that ``hangs togethers as an agenda for systemic changes in the production system and the improved integration of support functions.

  11. Looking beyond Lewis Structures: A General Chemistry Molecular Modeling Experiment Focusing on Physical Properties and Geometry

    Science.gov (United States)

    Linenberger, Kimberly J.; Cole, Renee S.; Sarkar, Somnath

    2011-01-01

    We present a guided-inquiry experiment using Spartan Student Version, ready to be adapted and implemented into a general chemistry laboratory course. The experiment provides students an experience with Spartan Molecular Modeling software while discovering the relationships between the structure and properties of molecules. Topics discussed within…

  12. An Innovative Near-Peer Mentoring Model for Undergraduate and Secondary Students: STEM Focus

    Science.gov (United States)

    Tenenbaum, Laura S.; Anderson, Margery K.; Jett, Marti; Yourick, Debra L.

    2014-01-01

    This study examined a novel mentoring model, "near-peer mentorship," that supports the development of mentee and mentor, incorporates established principles of mentoring, and offers unique opportunities to integrate research and teaching in a science, technology, engineering, and mathematics (STEM) internship. Using qualitative methods,…

  13. The story of mathematics

    CERN Document Server

    Mankiewicz, Richard

    2000-01-01

    Questioning how mathematics has evolved over the centuries and for what reasons; how human endeavour and changes in the way we live have been dependent on mathematics, this book tells the story of the impact this intellectual activity has had across cultures and civilizations. It shows how, far from being just the obsession of an elite group of philosophers, priests and scientists, mathematics has in some shape or other entered every area of human activity. The mysterious tally sticks of prehistoric peoples and the terrestial maps used for trade, exploration and warfare; the perennial fascination with the motions of heavenly bodies and changing perspectives on the art and science of vision; all are testament to a mathematics at the heart of history. The path of this changing discipline is marked by a wealth of images, from medieval manuscripts to the unsettling art of Dali or Duchamp, from the austere beauty of Babylonian clay tablets to the delicate complexity of computer-generated images. The text encompass...

  14. Implementation of FFT convolution and multigrid superposition models in the FOCUS RTP system

    Science.gov (United States)

    Miften, Moyed; Wiesmeyer, Mark; Monthofer, Suzanne; Krippner, Ken

    2000-04-01

    In radiotherapy treatment planning, convolution/superposition algorithms currently represent the best practical approach for accurate photon dose calculation in heterogeneous tissues. In this work, the implementation, accuracy and performance of the FFT convolution (FFTC) and multigrid superposition (MGS) algorithms are presented. The FFTC and MGS models use the same `TERMA' calculation and are commissioned using the same parameters. Both models use the same spectra, incorporate the same off-axis softening and base incident lateral fluence on the same measurements. In addition, corrections are explicitly applied to the polyenergetic and parallel kernel approximations, and electron contamination is modelled. Spectra generated by Monte Carlo (MC) modelling of treatment heads are used. Calculations using the MC spectra were in excellent agreement with measurements for many linear accelerator types. To speed up the calculations, a number of calculation techniques were implemented, including separate primary and scatter dose calculation, the FFT technique which assumes kernel invariance for the convolution calculation and a multigrid (MG) acceleration technique for the superposition calculation. Timing results show that the FFTC model is faster than MGS by a factor of 4 and 8 for small and large field sizes, respectively. Comparisons with measured data and BEAM MC results for a wide range of clinical beam setups show that (a) FFTC and MGS doses match measurements to better than 2% or 2 mm in homogeneous media; (b) MGS is more accurate than FFTC in lung phantoms where MGS doses are within 3% or 3 mm of BEAM results and (c) FFTC overestimates the dose in lung by a maximum of 9% compared to BEAM.

  15. A case study of a team-based, quality-focused compensation model for primary care providers.

    Science.gov (United States)

    Greene, Jessica; Hibbard, Judith H; Overton, Valerie

    2014-06-01

    In 2011, Fairview Health Services began replacing their fee-for-service compensation model for primary care providers (PCPs), which included an annual pay-for-performance bonus, with a team-based model designed to improve quality of care, patient experience, and (eventually) cost containment. In-depth interviews and an online survey of PCPs early after implementation of the new model suggest that it quickly changed the way many PCPs practiced. Most PCPs reported a shift in orientation toward quality of care, working more collaboratively with their colleagues and focusing on their full panel of patients. The majority reported that their quality of care had improved because of the model and that their colleagues' quality had to. The comprehensive change did, however, result in lower fee-for-service billing and reductions in PCP satisfaction. While Fairview's compensation model is still a work in progress, their early experiences can provide lessons for other delivery systems seeking to reform PCP compensation.

  16. Ion probe beam experiments and kinetic modeling in a dense plasma focus Z-pinch

    Energy Technology Data Exchange (ETDEWEB)

    Schmidt, A., E-mail: schmidt36@llnl.gov; Ellsworth, J., E-mail: schmidt36@llnl.gov; Falabella, S., E-mail: schmidt36@llnl.gov; Link, A., E-mail: schmidt36@llnl.gov; McLean, H., E-mail: schmidt36@llnl.gov; Rusnak, B., E-mail: schmidt36@llnl.gov; Sears, J., E-mail: schmidt36@llnl.gov; Tang, V., E-mail: schmidt36@llnl.gov [Lawrence Livermore National Laboratory, 7000 East Avenue, Livermore CA 94550 (United States); Welch, D. [Voss Scientific, LLC, 418 Washington St SE, Albuquerque NM 87108 (United States)

    2014-12-15

    The Z-pinch phase of a dense plasma focus (DPF) emits multiple-MeV ions in a ∼cm length. The mechanisms through which these physically simple devices generate such high energy beams in a relatively short distance are not fully understood. We are exploring the origins of these large gradients using measurements of an ion probe beam injected into a DPF during the pinch phase and the first kinetic simulations of a DPF Z-pinch. To probe the accelerating fields in our table top experiment, we inject a 4 MeV deuteron beam along the z-axis and then sample the beam energy distribution after it passes through the pinch region. Using this technique, we have directly measured for the first time the acceleration of an injected ion beam. Our particle-in-cell simulations have been benchmarked on both a kJ-scale DPF and a MJ-scale DPF. They have reproduced experimentally measured neutron yields as well as ion beams and EM oscillations which fluid simulations do not exhibit. Direct comparisons between the experiment and simulations enhance our understanding of these plasmas and provide predictive design capability for accelerator and neutron source applications.

  17. Remigration and Telling about It: Stories of Estonians from Russia

    Directory of Open Access Journals (Sweden)

    Anu Korb

    2008-08-01

    Full Text Available I will analyse the stories which focus on the reasons for returning toEstonia and remigration and have been written and told by Estonians who were born in Russia and returned to their motherland. These people returned to Estonia during 1941–1958 until the time Estonia became newly independent. Their ancestors had migrated to the rural areas of Russia since the middle of the 19th century.Stories about returning to homeland and adapting to the new environment have for a long time been limited to specific groups of people. They reached wider audiences after Estonia regained its independence and censorship weakened in Russia, and also as a result of the so-called biography boom in Eastern Europe. The context, time and situation of recording a narration or narrative shape the tales and can be repeatedly reassessed in the course of time.Stories about returning to homeland are both individual and collective; they express the experience of individuals as well as of a community or group. The stories of Estonians from certain regions are rather similar. The time and reasons for returning – forced or voluntary – have also had an impact on the stories.People do not mention shameful events in their lives or describe them only briefly. Even though this return of Estonians is not migration across state borders, most of these stories can still be classified as tales of traditional remigration. These stories give us information about the migration behaviour of remigrated Estonians and the emotions, attitudes and values associated with returning.

  18. Study of Characters in Story of School Principal (Modir Madrese

    Directory of Open Access Journals (Sweden)

    Ghadamzli Sarrami

    2013-05-01

    demonstrate symbol of each different guilds in the community, meanwhile none of personifications represented by nomenclature, ideas by characters and narration of myriad characters expressed by school principal composed of 81 figures plus classification of characters in five categories (main heroes, protagonists, antagonists, ordinary persons and walk on people all of them well criticized and analyzed finally the characteristics of ethics, deed and faith except the protagonist and main heroes who form the tenet of the story reviewed by a lot of illustrations.  The epilogue composes of comparison of the above story with Quranic hero focused stories while the school principal (Modir Madrese counted as hero focused fiction.

  19. Study of Characters in Story of School Principal (Modir Madrese

    Directory of Open Access Journals (Sweden)

    Dr Ghadamzli Sarrami , Mohammad Moghiseh

    2013-01-01

    each different guilds in the community, meanwhile none of personifications represented by nomenclature, ideas by characters and narration of myriad characters expressed by school principal composed of 81 figures plus classification of characters in five categories (main heroes, protagonists, antagonists, ordinary persons and walk on people all of them well criticized and analyzed finally the characteristics of ethics, deed and faith except the protagonist and main heroes who form the tenet of the story reviewed by a lot of illustrations. The epilogue composes of comparison of the above story with Quranic hero focused stories while the school principal (Modir Madrese counted as hero focused fiction.

  20. Study of Characters in Story of School Principal (Modir Madrese

    Directory of Open Access Journals (Sweden)

    Ghadamzli Sarrami

    2013-04-01

    individual characters demonstrate symbol of each different guilds in the community, meanwhile none of personifications represented by nomenclature, ideas by characters and narration of myriad characters expressed by school principal composed of 81 figures plus classification of characters in five categories (main heroes, protagonists, antagonists, ordinary persons and walk on people all of them well criticized and analyzed finally the characteristics of ethics, deed and faith except the protagonist and main heroes who form the tenet of the story reviewed by a lot of illustrations.  The epilogue composes of comparison of the above story with Quranic hero focused stories while the school principal (Modir Madrese counted as hero focused fiction. Â

  1. Modeling focusing characteristics of low Fnumber diffractive optical elements with continuous relief fabricated by laser direct writing.

    Science.gov (United States)

    Shan, Mingguang; Tan, Jiubin

    2007-12-10

    A theoretical model is established using Rayleigh-Sommerfeld diffraction theory to describe the diffraction focusing characteristics of low F-number diffractive optical elements with continuous relief fabricated by laser direct writing, and continuous-relief diffractive optical elements with a design wavelength of 441.6nm and a F-number of F/4 are fabricated and measured to verify the validity of the diffraction focusing model. The measurements made indicate that the spot size is 1.75mum and the diffraction efficiency is 70.7% at the design wavelength, which coincide well with the theoretical results: a spot size of 1.66mum and a diffraction efficiency of 71.2%.

  2. Bioengineered silk scaffolds in 3D tissue modeling with focus on mammary tissues.

    Science.gov (United States)

    Maghdouri-White, Yas; Bowlin, Gary L; Lemmon, Christopher A; Dréau, Didier

    2016-02-01

    In vitro generation of three-dimensional (3D) biological tissues and organ-like structures is a promising strategy to study and closely model complex aspects of the molecular, cellular, and physiological interactions of tissue. In particular, in vitro 3D tissue modeling holds promises to further our understanding of breast development. Indeed, biologically relevant 3D structures that combine mammary cells and engineered matrices have improved our knowledge of mammary tissue growth, organization, and differentiation. Several polymeric biomaterials have been used as scaffolds to engineer 3D mammary tissues. Among those, silk fibroin-based biomaterials have many biologically relevant properties and have been successfully used in multiple medical applications. Here, we review the recent advances in engineered scaffolds with an emphasis on breast-like tissue generation and the benefits of modified silk-based scaffolds.

  3. Review: Exploring anticarcinogenic agents in a rat hepatocarcinogenesis model--focus on selenium and statins.

    Science.gov (United States)

    Björkhem-Bergman, Linda; Ekström, Lena; Eriksson, Lennart C

    2012-01-01

    In this review, we describe a rat model for chemically induced hepatocarcinogenesis that can be used for studying the anticarcinogenic effects of different agents. In this model the process of carcinogenesis can be followed through the different stages of initiation, promotion and progression. Mechanistic studies of anticarcinogenic agents can be carried out and two examples are given by studies on selenium and statins as anticarcinogenic agents. These compounds suppress cancer via different mechanisms. In the case of selenium the induction of glutathione peroxidase 4 and inhibition of lipid peroxidation might be a part of the anticarcinogenic effect. In the case of statins, the inhibition of ubiquinone synthesis, as well as of the selenium-containing enzyme thioredoxin reductase 1 (TrxR1) might explain their anticarcinogenic properties. Interestingly, also in the case of selenium the inhibited carcinogenesis was associated with reduced TrxR activity, indicating an important role for this enzyme in carcinogenesis.

  4. Multidisciplinary Modelling Tools for Power Electronic Circuits:with Focus on High Power Modules

    OpenAIRE

    Bahman, Amir Sajjad

    2015-01-01

    This thesis presents multidisciplinary modelling techniques in a Design For Reliability (DFR) approach for power electronic circuits. With increasing penetration of renewable energy systems, the demand for reliable power conversion systems is becoming critical. Since a large part of electricity is processed through power electronics, highly efficient, sustainable, reliable and cost-effective power electronic devices are needed. Reliability of a product is defined as the ability to perform wit...

  5. Latent Gaussian modeling and INLA: A review with focus on space-time applications

    OpenAIRE

    Opitz, Thomas

    2016-01-01

    Bayesian hierarchical models with latent Gaussian layers have proven very flexible in capturing com- plex stochastic behavior and hierarchical structures in high-dimensional spatial and spatio-temporal data. Whereas simulation-based Bayesian inference through Markov Chain Monte Carlo may be hampered by slow convergence and numerical instabilities, the inferential framework of Integrated Nested Laplace Approximation (INLA) is capable to provide accurate and relatively fast analytical approxima...

  6. Employeeship concept: An interactive model of work relationships focused on leader and follower behaviors

    OpenAIRE

    Bertlett, Johan; Johansson, Curt R; Arvidsson, Marcus

    2011-01-01

    The purpose is to present a theoretical model of the concept employeeship. Employeeship concerns all employees and covers the vertical perspective of work behaviors and relationships between formal leaders and followers, and the horizontal perspective between co-workers on all organizational levels. This enables the study of both formal and informal leadership, authentically recognizing that all employees are possible leaders and that leadership emerges in the relationship between one leading...

  7. Animal models of motivation for drinking in rodents with a focus on opioid receptor neuropharmacology.

    Science.gov (United States)

    Koob, George F; Roberts, Amanda J; Kieffer, Brigitte L; Heyser, Charles J; Katner, Simon N; Ciccocioppo, Roberto; Weiss, Friedbert

    2003-01-01

    Ethanol, like other drugs of abuse, has motivating properties that can be developed as animal models of self-administration. A major strength of the operant approach where an animal must work to obtain ethanol is that it reduces confounds due to palatability and controls for nonspecific malaise-inducing effects. In the domain of opioid peptide systems, limited access paradigms have good predictive validity. In addition, animal models of excessive drinking-either environmentally or genetically induced-also appear sensitive to blockade or inactivation of opioid peptide receptors. Ethanol availability can be predicted by cues associated with positive reinforcement, and these models are sensitive to the administration of opioid antagonists. Perhaps most exciting are the recent results suggesting that the key element in opioid peptide systems that is important for the positive reinforcing effects of ethanol is the mu-opioid receptor. How exactly ethanol modulates mu-receptor function will be a major challenge of future research. Nevertheless, the apparently critical role of the mu receptor in ethanol reinforcement refocuses the neuropharmacology of ethanol reinforcement in the opioid peptide domain and opens a novel avenue for exploring medications for treating alcoholism.

  8. Polydimethylsiloxane embedded mouse aorta ex vivo perfusion model: proof-of-concept study focusing on atherosclerosis.

    Science.gov (United States)

    Wang, Xueya; Wolf, Marc P; Keel, Rahel Bänziger; Lehner, Roman; Hunziker, Patrick R

    2012-07-01

    Existing mouse artery ex vivo perfusion models have utilized arteries such as carotid, uterine, and mesenteric arteries, but not the aorta. However, the aorta is the principal vessel analyzed for atherosclerosis studies in vivo. We have devised a mouse aorta ex vivo perfusion model that can bridge this gap. Aortas from apoE((-/-)) mice are embedded in a transparent, gas-permeable, and elastic polymer matrix [polydimethylsiloxane (PDMS)] and artificially perfused with cell culture medium under cell culture conditions. After 24 h of artificial ex vivo perfusion, no evidence of cellular apoptosis is detected. Utilizing a standard confocal microscope, it is possible to image specific receptor targeting of cells in atherosclerotic plaques during 24 h. Imaging motion artifacts are minimal due to the polymer matrix embedding. Re-embedding of the aorta enables tissue sectioning and immuno-histochemical analysis. The ex vivo data are validated by comparison with in vivo experiments. This model can save animal lives via production of multiple endpoints in a single experiment, is easy to apply, and enables straightforward comparability with pre-existing atherosclerosis in vivo data. It is suited to investigate atherosclerotic disease in particular and vascular biology in general.

  9. Investigation of cellular and molecular responses to pulsed focused ultrasound in a mouse model.

    Directory of Open Access Journals (Sweden)

    Scott R Burks

    Full Text Available Continuous focused ultrasound (cFUS has been widely used for thermal ablation of tissues, relying on continuous exposures to generate temperatures necessary to induce coagulative necrosis. Pulsed FUS (pFUS employs non-continuous exposures that lower the rate of energy deposition and allow cooling to occur between pulses, thereby minimizing thermal effects and emphasizing effects created by non-thermal mechanisms of FUS (i.e., acoustic radiation forces and acoustic cavitation. pFUS has shown promise for a variety of applications including drug and nanoparticle delivery; however, little is understood about the effects these exposures have on tissue, especially with regard to cellular pro-homing factors (growth factors, cytokines, and cell adhesion molecules. We examined changes in murine hamstring muscle following pFUS or cFUS and demonstrate that pFUS, unlike cFUS, has little effect on the histological integrity of muscle and does not induce cell death. Infiltration of macrophages was observed 3 and 8 days following pFUS or cFUS exposures. pFUS increased expression of several cytokines (e.g., IL-1α, IL-1β, TNFα, INFγ, MIP-1α, MCP-1, and GMCSF creating a local cytokine gradient on days 0 and 1 post-pFUS that returns to baseline levels by day 3 post-pFUS. pFUS exposures induced upregulation of other signaling molecules (e.g., VEGF, FGF, PlGF, HGF, and SDF-1α and cell adhesion molecules (e.g., ICAM-1 and VCAM-1 on muscle vasculature. The observed molecular changes in muscle following pFUS may be utilized to target cellular therapies by increasing homing to areas of pathology.

  10. Soft X-ray Emission Optimization Studies with Krypton and Xenon Gases in Plasma Focus Using Lee Model

    Science.gov (United States)

    Akel, Mohamad

    2013-10-01

    The X-ray emission properties of krypton and xenon plasmas are numerically investigated using corona plasma equilibrium model. Numerical experiments have been investigated on various low energy plasma focus devices with Kr and Xe filling gases using Lee model. The Lee model was applied to characterize and to find the optimum combination of soft X-ray yields (Ysxr) for krypton (~4 Å) and xenon (~3 Å) plasma focus. These combinations give Ysxr = 0.018 J for krypton, and Ysxr = 0.5 J for xenon. Scaling laws on Kr and Xe soft X-ray yields, in terms of storage energies E0, peak discharge current Ipeak and focus pinch current Ipinch were found over the range from 2.8 to 900 kJ. Soft X-ray yields scaling laws in terms of storage energies were found to be as and for Kr and Xe, respectively, (E0 in kJ and Ysxr in J) with the scaling showing gradual deterioration as E0 rises over the range. The maximum soft X-ray yields are found to be about 0.5 and 27 J from krypton and xenon, respectively, for storage energy of 900 kJ. The optimum efficiencies for soft X-ray yields (0.0002 % for Kr) and (0.0047 % for Xe) are with capacitor bank energies of 67.5 and 225 kJ, respectively.

  11. A New Approach To Focused Crawling: Combination of Text summarizing With Neural Networks and Vector Space Model

    Directory of Open Access Journals (Sweden)

    Fahim Mohammadi

    2013-07-01

    Full Text Available Focused crawlers are programs designed to browse the Web anddownload pages on a specific topic. They are used for answeringuser queries or for building digital libraries on a topic specifiedby the user. In this article we will show how summarizing of webpages is needed for improving performance of a crawler whichuses vector space model to rank the web pages. A neural networkis trained to learn the relevant characteristics of sentences thatshould be included in the summary of a web page. Then theneural network will be used as a filter to summarize web pages.Finally, the crawler will use vector space model to ranksummaries instead of web pages.

  12. Criteria of validity for animal models of psychiatric disorders: focus on anxiety disorders and depression

    Directory of Open Access Journals (Sweden)

    Belzung Catherine

    2011-11-01

    Full Text Available Abstract Animal models of psychiatric disorders are usually discussed with regard to three criteria first elaborated by Willner; face, predictive and construct validity. Here, we draw the history of these concepts and then try to redraw and refine these criteria, using the framework of the diathesis model of depression that has been proposed by several authors. We thus propose a set of five major criteria (with sub-categories for some of them; homological validity (including species validity and strain validity, pathogenic validity (including ontopathogenic validity and triggering validity, mechanistic validity, face validity (including ethological and biomarker validity and predictive validity (including induction and remission validity. Homological validity requires that an adequate species and strain be chosen: considering species validity, primates will be considered to have a higher score than drosophila, and considering strains, a high stress reactivity in a strain scores higher than a low stress reactivity in another strain. Pathological validity corresponds to the fact that, in order to shape pathological characteristics, the organism has been manipulated both during the developmental period (for example, maternal separation: ontopathogenic validity and during adulthood (for example, stress: triggering validity. Mechanistic validity corresponds to the fact that the cognitive (for example, cognitive bias or biological mechanisms (such as dysfunction of the hormonal stress axis regulation underlying the disorder are identical in both humans and animals. Face validity corresponds to the observable behavioral (ethological validity or biological (biomarker validity outcomes: for example anhedonic behavior (ethological validity or elevated corticosterone (biomarker validity. Finally, predictive validity corresponds to the identity of the relationship between the triggering factor and the outcome (induction validity and between the effects of

  13. Computational Intelligence Modeling of the Macromolecules Release from PLGA Microspheres-Focus on Feature Selection.

    Directory of Open Access Journals (Sweden)

    Hossam M Zawbaa

    Full Text Available Poly-lactide-co-glycolide (PLGA is a copolymer of lactic and glycolic acid. Drug release from PLGA microspheres depends not only on polymer properties but also on drug type, particle size, morphology of microspheres, release conditions, etc. Selecting a subset of relevant properties for PLGA is a challenging machine learning task as there are over three hundred features to consider. In this work, we formulate the selection of critical attributes for PLGA as a multiobjective optimization problem with the aim of minimizing the error of predicting the dissolution profile while reducing the number of attributes selected. Four bio-inspired optimization algorithms: antlion optimization, binary version of antlion optimization, grey wolf optimization, and social spider optimization are used to select the optimal feature set for predicting the dissolution profile of PLGA. Besides these, LASSO algorithm is also used for comparisons. Selection of crucial variables is performed under the assumption that both predictability and model simplicity are of equal importance to the final result. During the feature selection process, a set of input variables is employed to find minimum generalization error across different predictive models and their settings/architectures. The methodology is evaluated using predictive modeling for which various tools are chosen, such as Cubist, random forests, artificial neural networks (monotonic MLP, deep learning MLP, multivariate adaptive regression splines, classification and regression tree, and hybrid systems of fuzzy logic and evolutionary computations (fugeR. The experimental results are compared with the results reported by Szlȩk. We obtain a normalized root mean square error (NRMSE of 15.97% versus 15.4%, and the number of selected input features is smaller, nine versus eleven.

  14. Trends in biomedical engineering: focus on Patient Specific Modeling and Life Support Systems.

    Science.gov (United States)

    Dubini, Gabriele; Ambrosi, Davide; Bagnoli, Paola; Boschetti, Federica; Caiani, Enrico G; Chiastra, Claudio; Conti, Carlo A; Corsini, Chiara; Costantino, Maria Laura; D'Angelo, Carlo; Formaggia, Luca; Fumero, Roberto; Gastaldi, Dario; Migliavacca, Francesco; Morlacchi, Stefano; Nobile, Fabio; Pennati, Giancarlo; Petrini, Lorenza; Quarteroni, Alfio; Redaelli, Alberto; Stevanella, Marco; Veneziani, Alessandro; Vergara, Christian; Votta, Emiliano; Wu, Wei; Zunino, Paolo

    2011-01-01

    Over the last twenty years major advancements have taken place in the design of medical devices and personalized therapies. They have paralleled the impressive evolution of three-dimensional, non invasive, medical imaging techniques and have been continuously fuelled by increasing computing power and the emergence of novel and sophisticated software tools. This paper aims to showcase a number of major contributions to the advancements of modeling of surgical and interventional procedures and to the design of life support systems. The selected examples will span from pediatric cardiac surgery procedures to valve and ventricle repair techniques, from stent design and endovascular procedures to life support systems and innovative ventilation techniques.

  15. Accelerating Neuronal Aging in In Vitro Model Brain Disorders: a Focus on Reactive Oxygen Species

    Directory of Open Access Journals (Sweden)

    Priscila Britto Campos

    2014-10-01

    Full Text Available In this review, we discuss insights gained through the use of stem cell preparations regarding the modeling of neurological diseases, the need for aging neurons derived from pluripotent stem cells to further advance the study of late-onset adult neurological diseases, and the extent to which mechanisms linked to the mismanagement of ROS. The context of these issues can be revealed using the three disease states of Parkinson’s (PD, Alzheimer’s (AD, and schizophrenia, as considerable insights have been gained into these conditions through the use of stem cells in terms of disease etiologies and the role of oxidative stress. The latter subject is a primary area of interest of our group. After discussing the molecular models of accelerated aging, we highlight the role of ROS for the three diseases explored here. Importantly, we do not seek to provide an extensive account of all genetic mutations for each of the three disorders discussed in this review, but we aim instead to provide a conceptual framework that could maximize the gains from merging the approaches of stem cell microsystems and the study of oxidative stress in disease in order to optimize therapeutics and determine new molecular targets against oxidative stress that spare stem cell proliferation and development.

  16. Are invertebrates relevant models in ageing research? Focus on the effects of rapamycin on TOR.

    Science.gov (United States)

    Erdogan, Cihan Suleyman; Hansen, Benni Winding; Vang, Ole

    2016-01-01

    Ageing is the organisms increased susceptibility to death, which is linked to accumulated damage in the cells and tissues. Ageing is a complex process regulated by crosstalk of various pathways in the cells. Ageing is highly regulated by the Target of Rapamycin (TOR) pathway activity. TOR is an evolutionary conserved key protein kinase in the TOR pathway that regulates growth, proliferation and cell metabolism in response to nutrients, growth factors and stress. Comparing the ageing process in invertebrate model organisms with relatively short lifespan with mammals provides valuable information about the molecular mechanisms underlying the ageing process faster than mammal systems. Inhibition of the TOR pathway activity via either genetic manipulation or rapamycin increases lifespan profoundly in most invertebrate model organisms. This contribution will review the recent findings in invertebrates concerning the TOR pathway and effects of TOR inhibition by rapamycin on lifespan. Besides some contradictory results, the majority points out that rapamycin induces longevity. This suggests that administration of rapamycin in invertebrates is a promising tool for pursuing the scientific puzzle of lifespan prolongation.

  17. The Story of Azithromycin

    Directory of Open Access Journals (Sweden)

    Banić Tomišić, Z.

    2011-12-01

    the negotiations and signing of a contract between PLIVA, Croatian pharmaceutical company, the patent holder, and Pfizer, one of the world largest pharmaceutical companies in the field of proprietary research. The dihydrate form of azithromycin is also discussed. The azithromycin (i.e. Sumamed and Zithromax story, which dates from the second half of the last century, can be considered as the first and foremost example of successful knowledge and technology transfer in Croatia ever. On their web pages, the World Intellectual Property Organization (WIPO reports the PLIVA azithromycin story as a case study and excellent example of proactive licensing strategy. For the discovery of azithromycin, in addition to receiving numerous awards, in the year 2000, PLIVA's scientists D. Sc. S. Đokić and M. Sc. G. Kobrehel, together with the representatives from the US-based Pfizer, were granted the honorable titles of "Heroes of Chemistry 2000" by the American Chemical Society (ACS, a non-profit association of American chemists and chemical engineers, and the largest association of scientists in the world. This high award is rightly taken to be also recognition of the achievement of PLIVA's entire team working on azithromycin. The success of azithromycin has placed PLIVA among the few pharmaceutical companies in the world that have developed their own blockbuster drug, and has entitled Croatia to join a small group of nations that have developed a new antibiotic.

  18. Modelling of mineral dust for interglacial and glacial climate conditions with a focus on Antarctica

    Directory of Open Access Journals (Sweden)

    N. Sudarchikova

    2015-05-01

    Full Text Available The mineral dust cycle responds to climate variations and plays an important role in the climate system by affecting the radiative balance of the atmosphere and modifying biogeochemistry. Polar ice cores provide unique information about deposition of aeolian dust particles transported over long distances. These cores are a palaeoclimate proxy archive of climate variability thousands of years ago. The current study is a first attempt to simulate past interglacial dust cycles with a global aerosol–climate model ECHAM5-HAM. The results are used to explain the dust deposition changes in Antarctica in terms of quantitative contribution of different processes, such as emission, atmospheric transport and precipitation, which will help to interpret palaeodata from Antarctic ice cores. The investigated periods include four interglacial time slices: the pre-industrial control (CTRL, mid-Holocene (6000 yr BP; hereafter referred to as "6 kyr", last glacial inception (115 000 yr BP; hereafter "115 kyr" and Eemian (126 000 yr BP; hereafter "126 kyr". One glacial time interval, the Last Glacial Maximum (LGM (21 000 yr BP; hereafter "21 kyr", was simulated as well to be a reference test for the model. Results suggest an increase in mineral dust deposition globally, and in Antarctica, in the past interglacial periods relative to the pre-industrial CTRL simulation. Approximately two-thirds of the increase in the mid-Holocene and Eemian is attributed to enhanced Southern Hemisphere dust emissions. Slightly strengthened transport efficiency causes the remaining one-third of the increase in dust deposition. The moderate change in dust deposition in Antarctica in the last glacial inception period is caused by the slightly stronger poleward atmospheric transport efficiency compared to the pre-industrial. Maximum dust deposition in Antarctica was simulated for the glacial period. LGM dust deposition in Antarctica is substantially increased due to 2.6 times higher

  19. Transmembrane Signal Transduction in Oocyte Maturation and Fertilization: Focusing on Xenopus laevis as a Model Animal

    Directory of Open Access Journals (Sweden)

    Ken-ichi Sato

    2014-12-01

    Full Text Available Fertilization is a cell biological phenomenon of crucial importance for the birth of new life in a variety of multicellular and sexual reproduction species such as algae, animal and plants. Fertilization involves a sequence of events, in which the female gamete “egg” and the male gamete “spermatozoon (sperm” develop, acquire their functions, meet and fuse with each other, to initiate embryonic and zygotic development. Here, it will be briefly reviewed how oocyte cytoplasmic components are orchestrated to undergo hormone-induced oocyte maturation and sperm-induced activation of development. I then review how sperm-egg membrane interaction/fusion and activation of development in the fertilized egg are accomplished and regulated through egg coat- or egg plasma membrane-associated components, highlighting recent findings and future directions in the studies using Xenopus laevis as a model experimental animal.

  20. A Model of NEFA Dynamics with Focus on the Postprandial State

    DEFF Research Database (Denmark)

    Jelic, K.; Hallgreen, Christine E.; Colding-Jorgensen, M.

    2009-01-01

    To improve the understanding of the mechanisms underlying the behavior of plasma non-esterified fatty acids (NEFA) in the postprandial state, we have developed a physiology-based mathematical model of plasma NEFA dynamics. Known physiological mechanisms are quantified and used to describe NEFA...... dynamics. Insulin is the major regulator of NEFA metabolism in the postprandial state. Plasma NEFA levels are thus highly dependent on the insulin concentration, the insulin sensitivity of adipose tissue, and the maximal lipolytic rate. In the postabsorptive state, e.g., at low insulin, adipose tissue....... The result is a drop in plasma NEFA after a carbohydrate containing meal. When insulin returns to postabsorptive levels, a rebound in plasma NEFA often occurs. This rebound is due to a restoration of lipolysis, a decrease in NEFA reesterification by adipose tissue and an increased LPL-as insulin activates...

  1. Modeling cognitive trajectories within longitudinal studies: a focus on older adults.

    Science.gov (United States)

    Steinerman, Joshua R; Hall, Charles B; Sliwinski, Martin J; Lipton, Richard B

    2010-10-01

    The natural history of life span cognitive performance and its late-life determinants have been studied from an array of perspectives. Significant insights come from psychological disciplines, including cognitive, developmental, and neuropsychology, as well as from medical specialties, such as geriatrics, neurology, psychiatry, neuroradiology, and neuropathology, that contribute to the growing interdisciplinary scientific field: cognitive neuroscience of aging. This survey of longitudinal studies of aging suggests that disease-oriented investigations commonly do not adequately consider normative cognitive changes, whereas developmental studies do not sufficiently measure and model nonnormative cognitive aging. This article argues for an integrative perspective that considers both of these influences on cognitive trajectories and presents a series of methodological concerns that have not been addressed comprehensively. Interdisciplinary methods from longitudinal observational studies should be leveraged to enable translational interventions to promote brain longevity.

  2. A model for large-scale, interprofessional, compulsory cross-cultural education with an indigenous focus.

    Science.gov (United States)

    Kickett, Marion; Hoffman, Julie; Flavell, Helen

    2014-01-01

    Cultural competency training for health professionals is now a recognised strategy to address health disparities between minority and white populations in Western nations. In Australia, urgent action is required to "Close the Gap" between the health outcomes of Indigenous Australians and the dominant European population, and significantly, cultural competency development for health professionals has been identified as an important element to providing culturally safe care. This paper describes a compulsory interprofessional first-year unit in a large health sciences faculty in Australia, which aims to begin students on their journey to becoming culturally competent health professionals. Reporting primarily on qualitative student feedback from the unit's first year of implementation as well as the structure, learning objects, assessment, and approach to coordinating the unit, this paper provides a model for implementing quality wide-scale, interprofessional cultural competence education within a postcolonial context. Critical factors for the unit's implementation and ongoing success are also discussed.

  3. Customer Focused Product Design Using Integrated Model of Target Costing, Quality Function Deployment and Value Engineering

    Directory of Open Access Journals (Sweden)

    Hossein Rezaei Dolatabadi

    2013-01-01

    Full Text Available Target costing by integrating customer requirements, technical attributes and cost information into the product design phase and eliminating the non-value added functions, plays a vital role in different phases of the product life cycle. Quality Function Deployment (QFD and Value Engineering (VE are two techniques which can be used for applying target costing, successfully. The purpose of this paper is to propose an integrated model of target costing, QFD and VE to explore the role of target costing in managing product costs while promoting quality specifications meeting customers’ needs. F indings indicate that the integration of target costing, QFD and VE is an essential technique in managing the costs of production process. Findings also imply that integration of the three techniques provides a competitive cost advantage to companies.

  4. Can fuzzy logic bring complex problems into focus? Modeling imprecise factors in environmental policy

    Energy Technology Data Exchange (ETDEWEB)

    McKone, Thomas E.; Deshpande, Ashok W.

    2004-06-14

    In modeling complex environmental problems, we often fail to make precise statements about inputs and outcome. In this case the fuzzy logic method native to the human mind provides a useful way to get at these problems. Fuzzy logic represents a significant change in both the approach to and outcome of environmental evaluations. Risk assessment is currently based on the implicit premise that probability theory provides the necessary and sufficient tools for dealing with uncertainty and variability. The key advantage of fuzzy methods is the way they reflect the human mind in its remarkable ability to store and process information which is consistently imprecise, uncertain, and resistant to classification. Our case study illustrates the ability of fuzzy logic to integrate statistical measurements with imprecise health goals. But we submit that fuzzy logic and probability theory are complementary and not competitive. In the world of soft computing, fuzzy logic has been widely used and has often been the ''smart'' behind smart machines. But it will require more effort and case studies to establish its niche in risk assessment or other types of impact assessment. Although we often hear complaints about ''bright lines,'' could we adapt to a system that relaxes these lines to fuzzy gradations? Would decision makers and the public accept expressions of water or air quality goals in linguistic terms with computed degrees of certainty? Resistance is likely. In many regions, such as the US and European Union, it is likely that both decision makers and members of the public are more comfortable with our current system in which government agencies avoid confronting uncertainties by setting guidelines that are crisp and often fail to communicate uncertainty. But some day perhaps a more comprehensive approach that includes exposure surveys, toxicological data, epidemiological studies coupled with fuzzy modeling will go a long way in

  5. The landslide story

    NARCIS (Netherlands)

    Huang, R.; Fan, X.

    2013-01-01

    The catastrophic Wenchuan earthquake induced an unprecedented number of geohazards. The risk of heightened landslide frequency after a quake, with potential secondary effects such as river damming and subsequent floods, needs more focused attention.

  6. Sir Real. Cover Story.

    Science.gov (United States)

    Greenman, Geri

    2000-01-01

    Describes an art assignment that focuses on surrealist composition. Students learn about Sigmund Freud, artists of the Surrealist movement, and characteristics of Surrealism. The produce thumbnail sketches, locate photographic images to use as references, and then create Surrealist artworks. (CMK)

  7. The landslide story

    NARCIS (Netherlands)

    Huang, R.; Fan, Xuanmei

    2013-01-01

    The catastrophic Wenchuan earthquake induced an unprecedented number of geohazards. The risk of heightened landslide frequency after a quake, with potential secondary effects such as river damming and subsequent floods, needs more focused attention.

  8. Sir Real. Cover Story.

    Science.gov (United States)

    Greenman, Geri

    2000-01-01

    Describes an art assignment that focuses on surrealist composition. Students learn about Sigmund Freud, artists of the Surrealist movement, and characteristics of Surrealism. The produce thumbnail sketches, locate photographic images to use as references, and then create Surrealist artworks. (CMK)

  9. Students' learning as the focus for shared involvement between universities and clinical practice: a didactic model for postgraduate degree projects.

    Science.gov (United States)

    Öhlén, J; Berg, L; Björk Brämberg, E; Engström, Å; German Millberg, L; Höglund, I; Jacobsson, C; Lepp, M; Lidén, E; Lindström, I; Petzäll, K; Söderberg, S; Wijk, H

    2012-10-01

    In an academic programme, completion of a postgraduate degree project could be a significant means of promoting student learning in evidence- and experience-based practice. In specialist nursing education, which through the European Bologna process would be raised to the master's level, there is no tradition of including a postgraduate degree project. The aim was to develop a didactic model for specialist nursing students' postgraduate degree projects within the second cycle of higher education (master's level) and with a specific focus on nurturing shared involvement between universities and healthcare settings. This study embodies a participatory action research and theory-generating design founded on empirically practical try-outs. The 3-year project included five Swedish universities and related healthcare settings. A series of activities was performed and a number of data sources secured. Constant comparative analysis was applied. A didactic model is proposed for postgraduate degree projects in specialist nursing education aimed at nurturing shared involvement between universities and healthcare settings. The focus of the model is student learning in order to prepare the students for participation as specialist nurses in clinical knowledge development. The model is developed for the specialist nursing education, but it is general and could be applicable to various education programmes.

  10. Seafloor and sub-seafloor landslide evidences. GIS data model focused on geohazards

    Science.gov (United States)

    Leon, Ricardo; Gimenez, Julia; Medialdea, Teresa; Somoza, Luis; Gonzalez, Francisco Javier

    2016-04-01

    The wealth of landslide-information preserved over seafloor and inside stratigraphic horizons should be appropriately structured and modeled so that its storage in GIS format can be directly applied in the geohazard analysis. The main aim of risk analysis is to answer the "where, when and how" questions. In this sense, parameters related to: (i) geographical location, (ii) shape and magnitude of the event, (iii) age of event/s - period of recurrence; shall be carefully analyzed to be stored in an interoperable and accessible GIS structure that can be directly applied in the risk analysis. It is important that the above parameters will be stored separately of the trigger information (sedimentation rate, earthquakes, faults locations, seabed geology, etc...) but with a strong related link. The appropriate geographical representation of the landslide event inherits problems of the geomorphological maps and the standardized submarine geomorphological legend. This gives rise to considerations on how to represent-and store a landslide-event. We present a GIS submarine landslides catalogue of the Spanish continental margin and adjacent areas. It comprises the Atlantic and Mediterranean continental margins as well as hot-spot type volcanic islands and seamounts (Canary Archipelago). The catalogue, implemented in a geographic information system, stores a total of 317 submarine landslides and compiles information such as name, location, typology, age, volume, source, and lithology and published references. It is conceived as a first step in the submarine risk analysis, although other applications such as sedimentology, tectonic or volcanic studies or basin evolution are also taken into account.

  11. Transtheoretical Model-based Nursing Intervention on Lifestyle Change: A Review Focused on Intervention Delivery Methods.

    Science.gov (United States)

    Lee, Joo Yun; Park, Hyeoun-Ae; Min, Yul Ha

    2015-06-01

    The transtheoretical model (TTM) was used to provide tailored nursing for lifestyle management such as diet, physical activity, and smoking cessation. The present study aims to assess the provision of intervention delivery methods, intervention elements, and stage-matched interventions, in order to identify ways in which information technology is used in the TTM-based research. The relevant literature was selected by two researchers using inclusion criteria after searching for "TTM (transtheoretical or stage of change)" and "nursing" from the databases PubMed and CINAHL. The selected studies were categorized in terms of study characteristics, intervention delivery method, intervention element, and use and level of stage-matched intervention. A total of 35 studies were selected including eight studies that used information communication technology (ICT). Nine different intervention delivery methods were used, of which "face-to-face" was the most common at 24 times. Of the 35 studies, 26 provided stage-matched interventions. Seven different intervention elements were used, of which "counseling" was the most common at 27 times. Of all the intervention elements, tailored feedback used ICT the most at seven instances out of nine, and there was a significant difference in the rate of ICT usage among intervention elements. ICT is not yet actively used in the TTM-based nursing interventions. Stage-matched interventions and TTM concepts were shown to be in partial use also in the TTM-based interventions. Therefore, it is necessary to develop a variety of ways to use ICT in tailored nursing interventions and to use TTM frameworks and concepts. Copyright © 2015. Published by Elsevier B.V.

  12. Modeling the Kinetics of Enhanced Photo-Polymerization under a Collimated and a Reflecting Focused UV Laser

    Directory of Open Access Journals (Sweden)

    Jui-Teng Lin

    2014-05-01

    Full Text Available This study explored the kinetics of ultraviolet (UV laser photoinitiated polymerization in thick polymer systems to achieve improved polymerization efficiency and uniformity. The modeling system comprised an incident UV laser and its reflecting beam, which was focused by a concave mirror to compensate for the exponential decay in the absorbing medium. The polymerization kinetic equation was numerically solved for the initiator concentration. The crossover time was calculated and compared among single beam, two collimated beam and collimated plus reflecting focused-beam systems. For the single beam case, analytic formulas for the time dependent incident beam is derived and demonstrated by measured data. A theoretical crossover time is defined to analyze the measured data based on the dynamic moduli. Lastly, the polymerization boundary dynamics are illustrated, showing the advantage of the combined two beam system. The numerical results provide useful guidance and a novel means for accelerated uniform photo-polymerization, which cannot be achieved by other means.

  13. Using Stories (and Books as Scaffolding for Our Young Language Learners

    Directory of Open Access Journals (Sweden)

    Annie Hughes

    2010-07-01

    Full Text Available This paper sets out to showTeachers of English to young learners need to support their learners’ general cognitive development and learning along with language learningthe use of stories has a very important role in teaching English to young learners (TEYLthe use of stories and books can provide scaffolding for our young language learners in order to allow for acquisition of the target language in a meaningful and cognitively supportive waythe use of stories and books can be used to encourage our young learners to create more stories and books in the target languageyoung language learners can develop a focused and detailed understanding of language through interaction with stories and books.

  14. Ray Tracing through the Edge Focusing of Rectangular Benders and an Improved Model for the Los Alamos Proton Storage Ring

    Energy Technology Data Exchange (ETDEWEB)

    Kolski, Jeffrey S. [Los Alamos National Laboratory; Barlow, David B. [Los Alamos National Laboratory; Macek, Robert J. [Los Alamos National Laboratory; McCrady, Rodney C. [Los Alamos National Laboratory

    2011-01-01

    Particle ray tracing through simulated 3D magnetic fields was executed to investigate the effective quadrupole strength of the edge focusing of the rectangular bending magnets in the Los Alamos Proton Storage Ring (PSR). The particle rays receive a kick in the edge field of the rectangular dipole. A focal length may be calculated from the particle tracking and related to the fringe field integral (FINT) model parameter. This tech note introduces the baseline lattice model of the PSR and motivates the need for an improvement in the baseline model's vertical tune prediction, which differs from measurement by .05. An improved model of the PSR is created by modifying the fringe field integral parameter to those suggested by the ray tracing investigation. This improved model is then verified against measurement at the nominal PSR operating set point and at set points far away from the nominal operating conditions. Lastly, Linear Optics from Closed Orbits (LOCO) is employed in an orbit response matrix method for model improvement to verify the quadrupole strengths of the improved model.

  15. Modelling of spatio-temporal precipitation relevant for urban hydrology with focus on scales, extremes and climate change

    DEFF Research Database (Denmark)

    Sørup, Hjalte Jomo Danielsen

    Time series of precipitation are necessary for assessment of urban hydrological systems. In a changed climate this is challenging as climate model output is not directly comparable to observations at the scales relevant for urban hydrology. The focus of this PhD thesis is downscaling...... of precipitation to spatio-temporal scales used in urban hydrology. It investigates several observational data products and identifies relevant scales where climate change and precipitation can be assessed for urban use. Precipitation is modelled at different scales using different stochastic techniques. A weather...... generator is used to produce an artificial spatio-temporal precipitation product that can be used both directly in large scale urban hydrological modelling and for derivation of extreme precipitation statistics relevant for urban hydrology. It is discussed why precipitation time series from a changed...

  16. Extension of the Transdiagnostic Model to Focus on Intolerance of Uncertainty: A Review of the Literature and Implications for Treatment

    Science.gov (United States)

    Einstein, Danielle A

    2014-01-01

    This study reviews research on the construct of intolerance of uncertainty (IU). A recent factor analysis (Journal of Anxiety Disorders, 25, 2012, p. 533) has been used to extend the transdiagnostic model articulated by Mansell (2005, p. 141) to focus on the role of IU as a facet of the model that is important to address in treatment. Research suggests that individual differences in IU may compromise resilience and that individuals high in IU are susceptible to increased negative affect. The model extension provides a guide for the treatment of clients presenting with uncertainty in the context of either a single disorder or several comorbid disorders. By applying the extension, the clinician is assisted to explore two facets of IU, “Need for Predictability” and “Uncertainty Arousal.” PMID:25400336

  17. Presenting Data And Telling Stories

    Science.gov (United States)

    Eales, Philip; Wayne, Andrew; Tildsley, Kevin M.; Wilkinson, Tim; Prieto, Diego Fernandez

    2013-12-01

    Earth observation data are now readily available at a range of scales and becoming increasingly familiar to the general public. Observations built up over several decades enable us to show long-term change and tell increasingly complex stories about the Earth and other planets. Data visualisation and computer graphics can help present these stories to a non-specialist public audience. In addition to high visual quality and clear design, we have found it useful to present data within its geographical and scientific context, in natural colour, in a realistic and immersive environment, using familiar visual and physical metaphors. The internet increasingly allows direct communication with the public and this places renewed emphasis on basics such as good story-telling. Examples are shown of work in television, print and digital media, and from ESA's Earth observation and planetary exploration programmes.

  18. The novel as short story

    Directory of Open Access Journals (Sweden)

    Kirk Schlueter

    2013-06-01

    Full Text Available In recent history, the novel has been thought of and defined primarily as a long prose narrative. However, this has not been the case historically, as the original meaning of "novel" was for "a piece of news" or "a short story or novella." Returning to this original definition, I propose a new way of viewing the work known contemporarily as the novel as a collection, or sequence, of united short stories rather than a single indivisible work, with the component short stories or novellas comprising the sequence renamed as "novels." A brief examination of several classic works traditionally considered novels serves to illustrate how this change in definition will affect reading.

  19. Mystery in Sepedi detective stories

    Directory of Open Access Journals (Sweden)

    M.J. Mojalefa

    2007-07-01

    Full Text Available The aim of this article is to illustrate the importance of the concept “mystery” in the classification of Sepedi detective stories. Mystery is therefore first defined, and then some rules governing how mystery is created and sustained in a narrative are reviewed. Examples are given of how the writers of Sepedi detective stories mislead their readers in order to create mystery. Mystery is then examined according to five of its constituent elements, namely the real character of the detective, the name of the criminal, the identity of the victim, the evidence that reveals the mystery in the end, and the investigation that reveals the mystery. Each category is explored by citing relevant examples from Sepedi detective stories.

  20. UNDER THE SHADOW: A STORY

    Directory of Open Access Journals (Sweden)

    Huatse Gyal

    2015-03-01

    Full Text Available A short story: All through my schooling in Amdo, I admired the 'selfless soldiers' in the many stories that we were taught – stories that originated in the Chinese Communist revolution, and were supposed to provide the foundation for our new society, since the 1950s. Our heroes were modest, self-sacrificing, and thought only of the greater good of those around them. Comrade Lei Feng was one of those we admired most, especially in elementary school. At recess, the boys ran around with make-believe guns, pretending to be the exemplary and selfless soldiers we kept hearing about, willing to die because our country told us we should. ...

  1. Modelling and optimization of transient processes in line focusing power plants with single-phase heat transfer medium

    Science.gov (United States)

    Noureldin, K.; González-Escalada, L. M.; Hirsch, T.; Nouri, B.; Pitz-Paal, R.

    2016-05-01

    A large number of commercial and research line focusing solar power plants are in operation and under development. Such plants include parabolic trough collectors (PTC) or linear Fresnel using thermal oil or molten salt as the heat transfer medium (HTM). However, the continuously varying and dynamic solar condition represent a big challenge for the plant control in order to optimize its power production and to keep the operation safe. A better understanding of the behaviour of such power plants under transient conditions will help reduce defocusing instances, improve field control, and hence, increase the energy yield and confidence in this new technology. Computational methods are very powerful and cost-effective tools to gain such understanding. However, most simulation models described in literature assume equal mass flow distributions among the parallel loops in the field or totally decouple the flow and thermal conditions. In this paper, a new numerical model to simulate a whole solar field with single-phase HTM is described. The proposed model consists of a hydraulic part and a thermal part that are coupled to account for the effect of the thermal condition of the field on the flow distribution among the parallel loops. The model is specifically designed for large line-focusing solar fields offering a high degree of flexibility in terms of layout, condition of the mirrors, and spatially resolved DNI data. Moreover, the model results have been compared to other simulation tools, as well as experimental and plant data, and the results show very good agreement. The model can provide more precise data to the control algorithms to improve the plant control. In addition, short-term and accurate spatially discretized DNI forecasts can be used as input to predict the field behaviour in-advance. In this paper, the hydraulic and thermal parts, as well as the coupling procedure, are described and some validation results and results of simulating an example field are

  2. Full Modelling of High-Intensity Focused Ultrasound and Thermal Heating in the Kidney using Realistic Patient Models.

    Science.gov (United States)

    Suomi, Visa; Jaros, Jiri; Treeby, Bradley; Cleveland, Robin

    2017-07-28

    High-intensity focused ultrasound (HIFU) therapy can be used for non-invasive treatment of kidney (renal) cancer, but the clinical outcomes have been variable. In this study, the efficacy of renal HIFU therapy was studied using nonlinear acoustic and thermal simulations in three patients. The acoustic simulations were conducted with and without refraction in order to investigate its effect on the shape, size and pressure distribution at the focus. The values for the attenuation, sound speed, perfusion and thermal conductivity of the kidney were varied over the reported ranges to determine the effect of variability on heating. Furthermore, the phase aberration was studied in order to quantify the underlying phase shifts using a second order polynomial function. The ultrasound field intensity was found to drop on average 11.1 dB with refraction and 6.4 dB without refraction. Reflection at tissue interfaces was found to result in a loss less than 0.1 dB. Focal point splitting due to refraction significantly reduced the heating efficacy. Of all the tissue parameters, perfusion was found to affect the heating the most. Small changes in temperature were seen with varying attenuation and thermal conductivity, but no visible changes were present with sound speed variations. The aberration study revealed an underlying trend in the spatial distribution of the phase shifts. The results show that the efficacy of HIFU therapy in the kidney could be improved with aberration correction. A method is proposed by which patient specific pre-treatment calculations could be used to overcome the aberration and therefore make ultrasound treatment possible.

  3. Energy efficiency in multi-story buildings

    Directory of Open Access Journals (Sweden)

    Staritcyna Anastasiia

    2016-01-01

    Full Text Available In this project a research on energy efficiency of Malta house was provided, it is a residential multi-story building in Helsinki, Jätkäsaari area. This project describes introduction with a new heating system for residential dwellings, which uses only heated air. To maintain air temperature in comfort level heat recovery and district heating is used in the same system. The task was to research efficacy of the enclosure structures. For research the 3D model has been created in the program the Revit 2015 and Lumion 13. Thermotechnical calculation for three types of a design has been executed in the program U-value.net.

  4. Playing Sub-stories from Complex Movies

    Science.gov (United States)

    Respicio, Ana; Teixeira, Carlos

    Complex movies with different parallel lines of action, only intersecting in a small number of scenes, can be difficult to analyze. The present study sets out to provide the viewer with assisted automatic procedures designed to decompose and analyze the narrative from different possible perspectives. We propose a model for narrative decomposition, based on the interaction of characters. The production of a time-stamped screenplay is used to achieve movie annotation based on the screenplay's contents, providing information about scene boundaries and the action semantics therein. The analysis of the graph of main character relations enables the extraction of coherent sub-stories from the main narrative.

  5. Pediatric Palliative Care: A Personal Story

    Science.gov (United States)

    ... Try it free Find out why Close Pediatric Palliative Care: A Personal Story NINRnews Subscribe Subscribed Unsubscribe 312 ... patient—and her family. The story demonstrates how palliative care can positively influence a patient's and family's experience ...

  6. Constructing leadership identities through stories

    DEFF Research Database (Denmark)

    Frimann, Søren; Hersted, Lone

    2016-01-01

    This article analyzes the construction of leadership identities through stories found in four narrative interviews from a qualitative study and leadership development project based on social constructionism and action learning. We argue that leadership development and the construction of leadership...... narrative interviews about their challenges as leaders? In addition, how do these discursive constructions restrict or enable new perspectives, other voices, and the possibilities for learning and change? Our analysis identified traces of both modern and postmodern leadership discourses. We suggest...... that the concept of coauthoring is useful in developing leadership and leadership identities through reflexive dialogs and emerging stories....

  7. What a Story! Sharing Stories for Effective Learning and Training

    Science.gov (United States)

    Hernandez, Luis A.

    2008-01-01

    Adult learning theory and practice supports the common sense approach that lasting learning takes place when the learners have both a cognitive and emotional experience with the topic at hand. While learning is a complex individual process, it needs to be meaningful, familiar, and challenging in order for each person to learn. Story telling on…

  8. Education Technology Success Stories

    Science.gov (United States)

    West, Darrell M.; Bleiberg, Joshua

    2013-01-01

    Advances in technology are enabling dramatic changes in education content, delivery, and accessibility. Throughout history, new technologies have facilitated the exponential growth of human knowledge. In the early twentieth century, the focus was on the use of radios in education. But since then, innovators have seen technology as a way to improve…

  9. Story Telling: Crafting Identities

    Science.gov (United States)

    McMahon, Mary; Watson, Mark

    2013-01-01

    Career guidance clients are seeking to craft new identities that better position them in their careers. The focus of the present article is on narrative career counselling's potential contribution in providing a meaningful and useful experience for career guidance clients. To illustrate the potential of narrative career counselling, the story…

  10. Modeling the Impacts of Cetacean-Focused Tourism in Taiwan: Observations from Cetacean Watching Boats: 2002-2005

    Science.gov (United States)

    Tseng, Yung-Ping; Huang, Yu-Chin; Kyle, Gerard T.; Yang, Ming-Ching

    2011-01-01

    Cetacean-focused tourism in Taiwan has grown rapidly since 1997. This development, measured in terms of both number of tour boats and visitors, has resulted in many resource management challenges stemming from the absence of regulation and scientific data. To fill this void in empirical evidence, we used 464 sighting records from 2002 to 2005 to model the impact of cetacean-focused tourism. Cox proportional hazard analysis indicated cetacean avoidance responses to cetacean watching boats were strongly associated with pod size, mother-calf pairs, and cetacean-vessel distances. Mother-calf pairs abandoned their avoidance tactic by 55% compared to noncalf groups when tour boats approached. Second, the hazard ratio of abundance was 0.996, suggesting that the odds of encountering avoidance responses by the cetaceans decreased by 42% for every 100-member increase in the cetacean pod size. Last, distances maintained by boats from the cetaceans was positively related to avoidance responses (i.e., less avoidance behavior with closer interaction). Based on our findings, we have the following recommendations: (a) limit vessels from approaching mothers with calves, (b) limit vessels from approaching small groups of cetaceans, (c) reduced avoidance behavior to boat traffic may be a red flag for potential long-term disturbance, and (d) apply the "precautionary principle" based on the best scientific information available in cetacean-based tourism in Taiwan. These recommendations will help contribute to the sustainable development of cetacean-focused tourism in Taiwan.

  11. Modeling the impacts of cetacean-focused tourism in Taiwan: observations from cetacean watching boats: 2002-2005.

    Science.gov (United States)

    Tseng, Yung-Ping; Huang, Yu-Chin; Kyle, Gerard T; Yang, Ming-Ching

    2011-01-01

    Cetacean-focused tourism in Taiwan has grown rapidly since 1997. This development, measured in terms of both number of tour boats and visitors, has resulted in many resource management challenges stemming from the absence of regulation and scientific data. To fill this void in empirical evidence, we used 464 sighting records from 2002 to 2005 to model the impact of cetacean-focused tourism. Cox proportional hazard analysis indicated cetacean avoidance responses to cetacean watching boats were strongly associated with pod size, mother-calf pairs, and cetacean-vessel distances. Mother-calf pairs abandoned their avoidance tactic by 55% compared to noncalf groups when tour boats approached. Second, the hazard ratio of abundance was 0.996, suggesting that the odds of encountering avoidance responses by the cetaceans decreased by 42% for every 100-member increase in the cetacean pod size. Last, distances maintained by boats from the cetaceans was positively related to avoidance responses (i.e., less avoidance behavior with closer interaction). Based on our findings, we have the following recommendations: (a) limit vessels from approaching mothers with calves, (b) limit vessels from approaching small groups of cetaceans, (c) reduced avoidance behavior to boat traffic may be a red flag for potential long-term disturbance, and (d) apply the "precautionary principle" based on the best scientific information available in cetacean-based tourism in Taiwan. These recommendations will help contribute to the sustainable development of cetacean-focused tourism in Taiwan.

  12. Archrtypal Analysis of Bijan and Manije Story

    Directory of Open Access Journals (Sweden)

    Tayebeh Jafari

    2013-04-01

    Full Text Available  Abstract Manije and Bijan story, a poem by a great poet, Firdausi Tousi, like his other stories in Shahname is a story which can be analyzed by archetyoal approach. According to this approach, this story can be considered as the individuation of here of this story, Bijan, who voluntarily enters into the individuation and psychological growth by being called. In his perfection cycle which is started and in Iran, by the trickery of evil wise old (gorgin, Bijan meets his Anima of unconscious. Bijan, who lived in Ashkanian era as some researchers believe, is one of the prime characters in Shahnameh. From mythical point of view, Bijan story, which is known as one of ancient myths, is the indicator of feminine society in Iran. Bijan story, like Bahram Chobin, Rustam and Sohrab, Ardeshir Babakan, and Rustam and Esfandiar, is an independent story added to Shahnameh. The comparison of Bijan story with other stories of Shahnameh represents this issue that Ferdowsi composed Bijan story in his youth and just after Daghighi’s death. Because Bijan story, like most other stories of Shahnameh and other myths, has a quite symbolic structure and motifs, Jung archetypal point of view is helpful to discover a lot of mysteries. In the present article, Bijan story is analyzed from Jung’s archetypal point of view. According to this theory, there are a lot of symbols, motifs and archetypes in this story. There is a united structure in every story formed base on its plot thus, to discover the structure of a symbolic story is an important act.   The symbolic motif of Bijan story is reaching the perfection and the story structure is completely commensurate with this motif the move is started from Iran, which is the indicator of Bijan story’s consciousness, then the hero after getting individual experience in land of unconscious, Turan, comes back to Iran. Bijan voluntary goes on a dangerous and symbolic way as the hero. Actually he is the portrayal

  13. Dense Plasma Focus Modeling

    Energy Technology Data Exchange (ETDEWEB)

    Li, Hui [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Li, Shengtai [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Jungman, Gerard [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Hayes-Sterbenz, Anna Catherine [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-07-10

    Here we report on high-fidelity 2D and 3D numerical magnetohydrodynamic (MHD) simulations using the LA-COMPASS code to study the pinch formation dynamics in a DPF and the associated instabilities and neutron production.

  14. Revisiting Science in Culture: Science as Story Telling and Story Revising

    Directory of Open Access Journals (Sweden)

    Paul Grobstein

    2005-01-01

    Full Text Available Both science itself, and the human culture of which it is a part, would benefit from a story of science that encourages wider engagement with and participation in the processes of scientific exploration. Such a story, based on a close analysis of scientific method, is presented here. It is the story of science as story telling and story revising. The story of science as story suggests that science can and should serve three distinctive functions for humanity: providing stories that may increase (but never guarantee human well-being, serving as a supportive nexus for human exploration and story telling in general, and exemplifying a commitment to skepticism and a resulting open-ended and continuing exploration of what might yet be. Some practical considerations that would further the development and acceptance of such a story of science as a widely shared nexus of human activity are described.

  15. A Short Story with Long Results

    Science.gov (United States)

    Jackman, Norma F.

    1972-01-01

    After reading a short story, a sixth grade class became involved in an avid discussion, a debate, and dramatic play - all based on the short story. A vast amount of learning had taken place through the study of a single short story. (Author/DR)

  16. The Subversion of Metaphysical Detective Story

    Institute of Scientific and Technical Information of China (English)

    马雪晴

    2015-01-01

    Featured unexpected ending,unique approaches, subversion of the rules of traditional detective story,and unique themes,metaphysical detective story is quite different from these traditional ones.These character were clearly showed in Death and Compass.In this article,metaphysical features of the story are analyzed and the theme was discussed.

  17. The Effectiveness of Using Group Story-Mapping Strategy to Improve Reading Comprehension of Students with Learning Disabilities

    Science.gov (United States)

    Alturki, Nada

    2017-01-01

    The purpose of this study was to examine the effectiveness of using group story-mapping on ESL students with a learning disability in reading comprehension. The researcher focused on a specific graphic organizer in this study, called Group Story-Mapping. This strategy required students with learning disabilities involving reading comprehension to…

  18. Historical Short Stories as Nature of Science Instruction in Secondary Science Classrooms: Science Teachers' Implementation and Students' Reactions

    Science.gov (United States)

    Reid-Smith, Jennifer Ann

    2013-01-01

    This study explores the use of historical short stories as nature of science (NOS) instruction in thirteen secondary science classes. The stories focus on the development of science ideas and include statements and questions to draw students' and teachers' attention to key NOS ideas and misconceptions. This study used mixed methods to examine how…

  19. A fully integrated Earth System Model: focus on dynamical coupling of climatic and cryospheric model sub-systems

    Science.gov (United States)

    Morozova, Polina; Volodin, Evgeny; Rybak, Oleg; Huybrechts, Philippe; Korneva, Irina; Kaminskaia, Mariia

    2017-04-01

    Earth system models (ESMs) have been widely used in the recent years for complex studies of the climate system of the planet in the context of interactions between the atmosphere, oceans, ice sheets and the biosphere. Incorporation of the Earth syb-systems with very different spatial and temporal scales and response times into one model is really a challenging task. In particular, coupling of an AO GCM and ice sheet models of Greenland and Antarctic ice sheets (GrIS and AIS) requires application of special downscaling procedures. Within the frameworks of our research study, we implemented several coupling strategies. The choice of a strategy is dictated mostly by two factors - by the purpose of the research and by spatial resolution of an AO GCM. Several versions of the latter (called INMCM) were developed in the Institute of Numerical Mathematics (Moscow, Russia). For instance, the version aimed primarily for the relatively long numerical experiments (for e.g. palaeostudies) has spatial resolution of 5°×4°, 21 vertical layers in the atmospheric block, 2.5°×2°, 33 vertical layers in the oceanic block. To provide proper data exchange between the INMCM and GrIS and AIS models (spatial resolution 20×20 km), we employ rather simple buffer (sub-) models, describing regional heat and moisture diffusion. Applying buffer models enables to avoid systematic shifts in INMCM-generated precipitation fields and to much more realistically describe influence orographically driven precipitation (in Greenland) and elevation-temperature dependence. Novel versions of the INMCM with the spatial resolution of 2,5°×2° and higher generate much more realistic climatic fields, therefore the coupling procedure can be simplified to just averaging, resampling and remapping data from the AO GCM global domain to regional domains enclosing ice sheets. Increase in spatial resolution inevitably causes additional computational cost and reduces the area of the ESM application to

  20. An actor-focused model of justice rule adherence and violation: the role of managerial motives and discretion.

    Science.gov (United States)

    Scott, Brent A; Colquitt, Jason A; Paddock, E Layne

    2009-05-01

    Research on organizational justice has focused primarily on the receivers of just and unjust treatment. Little is known about why managers adhere to or violate rules of justice in the first place. The authors introduce a model for understanding justice rule adherence and violation. They identify both cognitive motives and affective motives that explain why managers adhere to and violate justice rules. They also draw distinctions among the justice rules by specifying which rules offer managers more or less discretion in their execution. They then describe how motives and discretion interact to influence justice-relevant actions. Finally, the authors incorporate managers' emotional reactions to consider how their actions may change over time. Implications of the model for theory, research, and practice are discussed. (c) 2009 APA, all rights reserved.

  1. Experiments and computational modeling focused on divertor and SOL optimization for advanced tokamak operation on DIII-D

    Science.gov (United States)

    Allen, S. L.; Boedo, J. A.; Bozek, A. S.; Brooks, N. H.; Carlstrom, T. N.; Casper, T. A.; Colchin, R. J.; Evans, T. E.; Fenstermacher, M. E.; Friend, M. E.; Isler, R. C.; Jayakumar, R.; Lasnier, C. J.; Leonard, A. W.; Mahdavi, M. A.; Maingi, R.; McKee, G. R.; Moyer, R. A.; Murakami, M.; Osborne, T. H.; O'Neill, R. C.; Petrie, T. W.; Porter, G. D.; Ramsey, A. T.; Schaffer, M. J.; Stangeby, P. C.; Stambaugh, R. D.; Wade, M. R.; Watking, J. G.; West, W. P.; Whyte, D. G.; Wolf, N. S.

    2001-03-01

    We present the results from DIII-D experiments and modeling focused on the divertor issues of an `Advanced Tokamak' (AT). Operation at high plasma pressure β with good energy confinement H requires core and divertor plasma shaping and current profile J( r) control with ECH current drive. Transport modeling indicates that the available DIII-D ECH power determines a density and temperature regime for sustained DIII-D AT experiments. We demonstrate that a high-δ, unbalanced double null divertor with cryopumping (D-2000) is a flexible AT divertor. Impurity levels in AT experiments have been reduced by careful alignment of the divertor tiles; this, in turn has changed the time evolution of the core J( r) profiles. New physics has been observed near the X-point and private flux regions, including flow reversal and recombination, that is important in understanding and controlling the flows and thereby the radiation in the divertor region, which reduces the divertor heat flux.

  2. Animacy detection in stories

    NARCIS (Netherlands)

    Karsdorp, F.; Meulen, M. van der; Meder, T.; Bosch, A.P.J. van den

    2015-01-01

    This paper presents a linguistically uninformed computational model for animacy classification. The model makes use of word n-grams in combination with lower dimensional word embedding representations that are learned from a web-scale corpus. We compare the model to a number of linguistically inform

  3. Ativação de modelos mentais no recontar de histórias por idosos Mental model activation in the recall of stories by older adults

    Directory of Open Access Journals (Sweden)

    Maria Alice de Mattos Pimenta Parente

    1999-01-01

    Full Text Available Recontar histórias é uma atividade complexa que envolve recursos da memória de curta duração (MCD e da memória episódica (ME. Estratégias direcionadas a objetivos e intenções particulares diminuem a sobrecarga da MCD e ativam a ME. Com o objetivo de estudar a influência do envelhecimento nestes mecanismos, estudamos o relato de uma história por dois grupos de adultos: 17 com 30 a 55 anos e 14 com mais de 60 anos. Os adultos mais jovens lembraram mais proposições do que os idosos, mas ambos grupos relembraram melhor as macroestruturas do que as microestruturas e não foi encontrada diferença no número de inferências, interferências e reconstruções. Entretanto, uma análise de ênfases dados à história, mostrou que jovens preferem relatar a seqüência de ações e idosos, encadeam os fatos de forma subjetiva, sugerindo que, devido à uma redução da memória de trabalho, utilizam-se mais das estratégias que recorrem às informações armazenadas na memória episódica, deixando transparecer suas representações mentais.Text comprehension is a complex activity that requires resources from short term memory (STM and from episodic memory (EM. Strategies directed to goals and intentions avoid an overload of the STM and activates the EM. To study the influence of aging on those mechanisms, we analyzed the recall of a story by two different groups of adults: 17 subjects, 30 to 50 years old, and 14 with more than 60 years of age. The younger group remembered more propositions than the elders, but both groups recalled better the macro than the microstructure. No differences regarding number of inference, interference, and reconstruction were found. Nevertheless, residual analysis showed that younger adults organized their recall telling the actions of the original story, whereas the older adults chose a subjective organization of the main facts, suggesting that due to a reduction of the working memory, the elderly elaborated

  4. Therapeutic Effects of Microbubbles Added to Combined High-Intensity Focused Ultrasound and Chemotherapy in a Pancreatic Cancer Xenograft Model

    Energy Technology Data Exchange (ETDEWEB)

    Yu, Mi Hye [Department of Radiology, Konkuk University Medical Center, Seoul 05030 (Korea, Republic of); Lee, Jae Young [Department of Radiology, Seoul National University Hospital, Seoul 03080 (Korea, Republic of); Kim, Hae Ri [Department of Pre-Dentistry, Gangneung-Wonju National University College of Dentistry, Gangneung 25457 (Korea, Republic of); Kim, Bo Ram; Park, Eun-Joo; Kim, Hoe Suk; Han, Joon Koo [Department of Radiology, Seoul National University Hospital, Seoul 03080 (Korea, Republic of); Choi, Byung Ihn [Department of Radiology, Chung-Ang University Hospital, Seoul 06973 (Korea, Republic of)

    2016-11-01

    To investigate whether high-intensity focused ultrasound (HIFU) combined with microbubbles enhances the therapeutic effects of chemotherapy. A pancreatic cancer xenograft model was established using BALB/c nude mice and luciferase-expressing human pancreatic cancer cells. Mice were randomly assigned to five groups according to treatment: control (n = 10), gemcitabine alone (GEM; n = 12), HIFU with microbubbles (HIFU + MB, n = 11), combined HIFU and gemcitabine (HIGEM; n = 12), and HIGEM + MB (n = 13). After three weekly treatments, apoptosis rates were evaluated using the terminal deoxynucleotidyl transferase-mediated dUTP nick end-labeling assay in two mice per group. Tumor volume and bioluminescence were monitored using high-resolution 3D ultrasound imaging and in vivo bioluminescence imaging for eight weeks in the remaining mice. The HIGEM + MB group showed significantly higher apoptosis rates than the other groups (p < 0.05) and exhibited the slowest tumor growth. From week 5, the tumor-volume-ratio relative to the baseline tumor volume was significantly lower in the HIGEM + MB group than in the control, GEM, and HIFU + MB groups (p < 0.05). Despite visible distinction, the HIGEM and HIGEM + MB groups showed no significant differences. High-intensity focused ultrasound combined with microbubbles enhances the therapeutic effects of gemcitabine chemotherapy in a pancreatic cancer xenograft model.

  5. Therapeutic effects of microbubble added to combined high-intensity focused ultrasound and chemotherapy in a pancreatic cancer xenograft model

    Energy Technology Data Exchange (ETDEWEB)

    Yu, Mi Hye [Dept. of Radiology, Konkuk University Medical Center, Seoul (Korea, Republic of); Lee, Jae Young; Kim, Bo Ram; Park, Eun Joo; Kim, Hoe Suk; Han, Joon Koo [Dept. of Radiology, Seoul National University Hospital, Seoul (Korea, Republic of); Kim, Hae Ri [Dept. of Pre-Dentistry, Gangneung-Wonju National University College of Dentistry, Gangneung (Korea, Republic of); Choi, Byung Ihn [Dept. of Radiology, Chung-Ang University Hospital, Seoul (Korea, Republic of)

    2016-09-15

    To investigate whether high-intensity focused ultrasound (HIFU) combined with microbubbles enhances the therapeutic effects of chemotherapy. A pancreatic cancer xenograft model was established using BALB/c nude mice and luciferase-expressing human pancreatic cancer cells. Mice were randomly assigned to five groups according to treatment: control (n = 10), gemcitabine alone (GEM; n = 12), HIFU with microbubbles (HIFU + MB, n = 11), combined HIFU and gemcitabine (HIGEM; n = 12), and HIGEM + MB (n = 13). After three weekly treatments, apoptosis rates were evaluated using the terminal deoxynucleotidyl transferase-mediated dUTP nick end-labeling assay in two mice per group. Tumor volume and bioluminescence were monitored using high-resolution 3D ultrasound imaging and in vivo bioluminescence imaging for eight weeks in the remaining mice. The HIGEM + MB group showed significantly higher apoptosis rates than the other groups (p < 0.05) and exhibited the slowest tumor growth. From week 5, the tumor-volume-ratio relative to the baseline tumor volume was significantly lower in the HIGEM + MB group than in the control, GEM, and HIFU + MB groups (p < 0.05). Despite visible distinction, the HIGEM and HIGEM + MB groups showed no significant differences. High-intensity focused ultrasound combined with microbubbles enhances the therapeutic effects of gemcitabine chemotherapy in a pancreatic cancer xenograft model.

  6. Archrtypal Analysis of Bijan and Manije Story

    Directory of Open Access Journals (Sweden)

    Tayebeh Jafari

    2013-05-01

    Full Text Available Abstract Manije and Bijan story, a poem by a great poet, Firdausi Tousi, like his other stories in Shahname is a story which can be analyzed by archetyoal approach. According to this approach, this story can be considered as the individuation of here of this story, Bijan, who voluntarily enters into the individuation and psychological growth by being called. In his perfection cycle which is started and in Iran, by the trickery of evil wise old (gorgin, Bijan meets his Anima of unconscious. Bijan, who lived in Ashkanian era as some researchers believe, is one of the prime characters in Shahnameh. From mythical point of view, Bijan story, which is known as one of ancient myths, is the indicator of feminine society in Iran. Bijan story, like Bahram Chobin, Rustam and Sohrab, Ardeshir Babakan, and Rustam and Esfandiar, is an independent story added to Shahnameh. The comparison of Bijan story with other stories of Shahnameh represents this issue that Ferdowsi composed Bijan story in his youth and just after Daghighi’s death. Because Bijan story, like most other stories of Shahnameh and other myths, has a quite symbolic structure and motifs, Jung archetypal point of view is helpful to discover a lot of mysteries. In the present article, Bijan story is analyzed from Jung’s archetypal point of view. According to this theory, there are a lot of symbols, motifs and archetypes in this story. There is a united structure in every story formed base on its plot thus, to discover the structure of a symbolic story is an important act.   The symbolic motif of Bijan story is reaching the perfection and the story structure is completely commensurate with this motif the move is started from Iran, which is the indicator of Bijan story’s consciousness, then the hero after getting individual experience in land of unconscious, Turan, comes back to Iran. Bijan voluntary goes on a dangerous and symbolic way as the hero. Actually he is the portrayal of a part of

  7. Reading Pictures for Story Comprehension Requires Mental Imagery Skills

    Directory of Open Access Journals (Sweden)

    Inouk E. Boerma

    2016-10-01

    Full Text Available We examined the role of mental imagery skills on story comprehension in 150 fifth graders (10-12-year-olds, when reading a narrative book chapter with alternating words and pictures (i.e., text blocks were alternated by one- or two-page picture spreads. A parallel group design was used, in which we compared our experimental book version, in which pictures were used to replace parts of the corresponding text, to two control versions, i.e., a text-only version and a version with the full story text and all pictures. Analyses showed an interaction between mental imagery and book version: children with higher mental imagery skills outperformed children with lower mental imagery skills on story comprehension after reading the experimental narrative. This was not the case for both control conditions. This suggests that children’s mental imagery skills significantly contributed to the mental representation of the story that they created, by successfully integrating information from both words and pictures. The results emphasize the importance of mental imagery skills for explaining individual variability in reading development. Implications for educational practice are that we should find effective ways to instruct children how to read pictures and how to develop and use their mental imagery skills. This will probably contribute to their mental models and therefore their story comprehension.

  8. Telling Stories of Career Assessment

    Science.gov (United States)

    McMahon, Mary; Watson, Mark

    2012-01-01

    In the field of career development, there is an acknowledged relationship between career assessment and career counseling. Traditional career assessment and more recent narrative approaches to career counseling are perceived as having an uneasy relationship because of their different philosophical bases. A sustainable future story for the field…

  9. Melting Pots: Family Stories & Recipes.

    Science.gov (United States)

    Weber, Judith Eichler

    Discussing the different ways people (including Chinese, Greek, African-American, English, and Cuban) celebrate with food, this book presents a brief account of various celebrations followed by a short story involving each celebration. Celebrations discussed in the book are family parties, birthday parties, school parties, surprise parties, and…

  10. Food Labels Tell the Story!

    Science.gov (United States)

    ... My World From the Label to the Table! Food Labels Tell the Story! What is in food? Food provides your body with all of the ... your food choices. Nutrition Facts—the Labels on Food Products Beginning in 1994, the US government began ...

  11. Teaching about Consumerism through Stories

    Science.gov (United States)

    Haas, Kay Parks

    2010-01-01

    One of the best methods in the English language arts classroom is to educate students through the world of stories. The beauty of storytelling is that it often has a more powerful impact on young adults than a didactic lecture or a textbook chapter. Many times students would say that they internalize a message much more willingly through reading a…

  12. Learning through Dramatic Story Presentation

    Science.gov (United States)

    Tindall, Evie

    2012-01-01

    The use of story with dramatic presentation approaches produces an engaging and powerful instructional choice for today's adult ESL educators. Two engaging and timed-tested approaches are Reader's Theater and Tableau Vivant. Both provide English language learners with content tailored to their abilities in addition to numerable opportunities to…

  13. The Story of the Neutrino

    CERN Document Server

    Rajasekaran, G

    2016-01-01

    This is an elementary review of the history and physics of neutrinos. The story of the discovery of neutrino mass through neutrino oscillations is described in some detail. Experiments on solar neutrinos and atmospheric neutrinos played an important part. Recent advances are summarized and future developments are indicated.

  14. Considerations for numerical modeling of the pulmonary circulation--a review with a focus on pulmonary hypertension.

    Science.gov (United States)

    Kheyfets, V O; O'Dell, W; Smith, T; Reilly, J J; Finol, E A

    2013-06-01

    Both in academic research and in clinical settings, virtual simulation of the cardiovascular system can be used to rapidly assess complex multivariable interactions between blood vessels, blood flow, and the heart. Moreover, metrics that can only be predicted with computational simulations (e.g., mechanical wall stress, oscillatory shear index, etc.) can be used to assess disease progression, for presurgical planning, and for interventional outcomes. Because the pulmonary vasculature is susceptible to a wide range of pathologies that directly impact and are affected by the hemodynamics (e.g., pulmonary hypertension), the ability to develop numerical models of pulmonary blood flow can be invaluable to the clinical scientist. Pulmonary hypertension is a devastating disease that can directly benefit from computational hemodynamics when used for diagnosis and basic research. In the present work, we provide a clinical overview of pulmonary hypertension with a focus on the hemodynamics, current treatments, and their limitations. Even with a rich history in computational modeling of the human circulation, hemodynamics in the pulmonary vasculature remains largely unexplored. Thus, we review the tasks involved in developing a computational model of pulmonary blood flow, namely vasculature reconstruction, meshing, and boundary conditions. We also address how inconsistencies between models can result in drastically different flow solutions and suggest avenues for future research opportunities. In its current state, the interpretation of this modeling technology can be subjective in a research environment and impractical for clinical practice. Therefore, considerations must be taken into account to make modeling reliable and reproducible in a laboratory setting and amenable to the vascular clinic. Finally, we discuss relevant existing models and how they have been used to gain insight into cardiopulmonary physiology and pathology.

  15. Experiencing Violence and Enacting Resilience: The Case Story of a Transgender Youth.

    Science.gov (United States)

    DiFulvio, Gloria T

    2015-11-01

    Research about victimization among sexual minority youth has focused on documenting the prevalence and consequences of such experiences. Lacking in the literature is an in-depth exploration of the social context of both risk and resilience in the face of violence. This is especially true for transgender youth who are largely absent from the dominant discourse. This case story provides an example of how one transgender youth interpreted and adaptively responded to the discrimination and prejudice she encountered. Katie's story illustrates the process of resilience. Despite the adversity she has faced, she shares stories of pride and strength in a culture that considers her as "other."

  16. Cavitation-induced damage of soft materials by focused ultrasound bursts: A fracture-based bubble dynamics model.

    Science.gov (United States)

    Movahed, Pooya; Kreider, Wayne; Maxwell, Adam D; Hutchens, Shelby B; Freund, Jonathan B

    2016-08-01

    A generalized Rayleigh-Plesset-type bubble dynamics model with a damage mechanism is developed for cavitation and damage of soft materials by focused ultrasound bursts. This study is linked to recent experimental observations in tissue-mimicking polyacrylamide and agar gel phantoms subjected to bursts of a kind being considered specifically for lithotripsy. These show bubble activation at multiple sites during the initial pulses. More cavities appear continuously through the course of the observations, similar to what is deduced in pig kidney tissues in shock-wave lithotripsy. Two different material models are used to represent the distinct properties of the two gel materials. The polyacrylamide gel is represented with a neo-Hookean elastic model and damaged based upon a maximum-strain criterion; the agar gel is represented with a strain-hardening Fung model and damaged according to the strain-energy-based Griffith's fracture criterion. Estimates based upon independently determined elasticity and viscosity of the two gel materials suggest that bubble confinement should be sufficient to prevent damage in the gels, and presumably injury in some tissues. Damage accumulation is therefore proposed to occur via a material fatigue, which is shown to be consistent with observed delays in widespread cavitation activity.

  17. Putting User Stories First: Experiences Adapting the Legacy Data Models and Information Architecture at NASA JPL's PO.DAAC to Accommodate the New Information Lifecycle Required by SWOT

    Science.gov (United States)

    McGibbney, L. J.; Hausman, J.; Laurencelle, J. C.; Toaz, R., Jr.; McAuley, J.; Freeborn, D. J.; Stoner, C.

    2016-12-01

    The Surface Water & Ocean Topography (SWOT) mission brings together two communities focused on a better understanding of the world's oceans and its terrestrial surface waters. U.S. and French oceanographers and hydrologists and international partners have joined forces to develop this new space mission. At NASA JPL's PO.DAAC, the team is currently engaged in the gathering of SWOT User Stores (access patterns, metadata requirements, primary and value added product requirements, data access protocols, etc.) to better inform the adaptive planning of what will be known as the next generation PO.DAAC Information Architecture (IA). The IA effort acknowledges that missions such as SWOT (and NISAR) have few or no precedent in terms of data volume, hot and cold storage, archival, analysis, existing system engineering complexities, etc. and that the only way we can better understand the projected impacts of such requirements is to interface directly with the User Community. Additionally, it also acknowledges that collective learning has taken place to understand certain limitations in the existing data models (DM) underlying the existing PO.DAAC Data Management and Archival System. This work documents an evolutionary, use case based, standards driven approach to adapting the legacy DM and accompanying knowledge representation infrastructure at NASA JPL's PO.DAAC to address forthcoming DAAC mission requirements presented by missions such as SWOT. Some of the topics covered in this evolution include, but are not limited to: How we are leveraging lessons learned from the development of existing DM (such as that generated for SMAP) in an attempt to map them to SWOT. What is the governance model for the SWOT IA? What are the `governing' entities? What is the hierarchy of the `governed entities'? How are elements grouped? How is the design-working group formed? How is model independence maintained and what choices/requirements do we have for the implementation language? The use of

  18. Ancient loons stories Pingree told me

    CERN Document Server

    Davis, Philip J

    2016-01-01

    The book is a collection of short stories, small anecdotes in the life of some historical characters. More concretely, it focuses on the oddities and singularities of some well-known historical figures, not only in science, but also in arts, politics and social sciences. … the book shows the fascination for ancient history, the treasures hidden in original sources and the importance of exploring unusual connections.-Javier Martinez, The European Mathematical Society, January 2013… a rambling, illuminating and thoroughly enjoyable bio/autobiographical and historical sketch, setting Pingree's immense erudition in its professional and intellectual context. Besides a string of amusing and intriguing anecdotes plentifully sprinkled with photos and sketches, this small volume supplies a valuable reminder of how complex, surprising and just plain strange the history of the exact sciences can be.-Kim Plofker, MAA Reviews, October 2012.

  19. Ion focusing

    Energy Technology Data Exchange (ETDEWEB)

    Cooks, Robert Graham; Baird, Zane; Peng, Wen-Ping

    2017-01-17

    The invention generally relates to apparatuses for focusing ions at or above ambient pressure and methods of use thereof. In certain embodiments, the invention provides an apparatus for focusing ions that includes an electrode having a cavity, at least one inlet within the electrode configured to operatively couple with an ionization source, such that discharge generated by the ionization source is injected into the cavity of the electrode, and an outlet. The cavity in the electrode is shaped such that upon application of voltage to the electrode, ions within the cavity are focused and directed to the outlet, which is positioned such that a proximal end of the outlet receives the focused ions and a distal end of the outlet is open to ambient pressure.

  20. Ultrasound-guided tissue fractionation by high intensity focused ultrasound in an in vivo porcine liver model.

    Science.gov (United States)

    Khokhlova, Tatiana D; Wang, Yak-Nam; Simon, Julianna C; Cunitz, Bryan W; Starr, Frank; Paun, Marla; Crum, Lawrence A; Bailey, Michael R; Khokhlova, Vera A

    2014-06-03

    The clinical use of high intensity focused ultrasound (HIFU) therapy for noninvasive tissue ablation has been recently gaining momentum. In HIFU, ultrasound energy from an extracorporeal source is focused within the body to ablate tissue at the focus while leaving the surrounding organs and tissues unaffected. Most HIFU therapies are designed to use heating effects resulting from the absorption of ultrasound by tissue to create a thermally coagulated treatment volume. Although this approach is often successful, it has its limitations, such as the heat sink effect caused by the presence of a large blood vessel near the treatment area or heating of the ribs in the transcostal applications. HIFU-induced bubbles provide an alternative means to destroy the target tissue by mechanical disruption or, at its extreme, local fractionation of tissue within the focal region. Here, we demonstrate the feasibility of a recently developed approach to HIFU-induced ultrasound-guided tissue fractionation in an in vivo pig model. In this approach, termed boiling histotripsy, a millimeter-sized boiling bubble is generated by ultrasound and further interacts with the ultrasound field to fractionate porcine liver tissue into subcellular debris without inducing further thermal effects. Tissue selectivity, demonstrated by boiling histotripsy, allows for the treatment of tissue immediately adjacent to major blood vessels and other connective tissue structures. Furthermore, boiling histotripsy would benefit the clinical applications, in which it is important to accelerate resorption or passage of the ablated tissue volume, diminish pressure on the surrounding organs that causes discomfort, or insert openings between tissues.

  1. Enhancing Canadian Teacher Education Using a Story Framework

    Science.gov (United States)

    Drake, Susan M.

    2010-01-01

    The "Accord on Initial Teacher Education" was created by the Canadian Deans of Education in 2006 to guide teacher educators across Canada. The "Story Model" (Drake et al., 1992) is aligned with the principles in the Accord and has proven useful in teacher education. Here it is explored as a framework for curriculum development…

  2. The Significance of Symbolic Elements in Lu Xun’s Short Stories

    Directory of Open Access Journals (Sweden)

    Tina Ilgo

    2010-12-01

    Full Text Available The present article interprets the symbolic elements in Lu Xun’s short stories which have been neglected in earlier studies about Lu Xun. I intend to show that the most obvious symbols in his fiction, like the iron room, the cannibalism, etc., have their counter balance in the animal symbols present in his work. Following this idea, I will focus on his less famous stories, such as A Comedy of Ducks and Some Rabbits and a Cat.

  3. Focused ultrasound enhanced molecular imaging and gene therapy for multifusion reporter gene in glioma-bearing rat model.

    Science.gov (United States)

    Yang, Feng-Yi; Chang, Wen-Yuan; Lin, Wei-Ting; Hwang, Jeng-Jong; Chien, Yi-Chun; Wang, Hsin-Ell; Tsai, Min-Lan

    2015-11-03

    The ability to monitor the responses of and inhibit the growth of brain tumors during gene therapy has been severely limited due to the blood-brain barrier (BBB). A previous study has demonstrated the feasibility of noninvasive in vivo imaging with 123I-2'-fluoro-2'-deoxy-5-iodo-1-β-D-arabinofuranosyluracil (123I-FIAU) for monitoring herpes simplex virus type 1 thymidine kinase (HSV1-tk) cancer gene expression in an experimental animal model. Here, we tested the enhancement of SPECT with 123I-FIAU and ganciclovir (GCV) treatment in brain tumors after BBB disruption induced by focused ultrasound (FUS) in the presence of microbubbles. We established an orthotopic F98 glioma-bearing rat model with trifusion reporter genes. The results of this study showed that the rat model of HSV1-tk-expressing glioma cells could be successfully detected by SPECT imaging after FUS-induced BBB disruption on day 10 after implantation. Compared to the control group, animals receiving the GCV with or without sonication exhibited a significant antitumor activity (P therapy in brain diseases.

  4. Identification of a Typical CSTR Using Optimal Focused Time Lagged Recurrent Neural Network Model with Gamma Memory Filter

    Directory of Open Access Journals (Sweden)

    S. N. Naikwad

    2009-01-01

    Full Text Available A focused time lagged recurrent neural network (FTLR NN with gamma memory filter is designed to learn the subtle complex dynamics of a typical CSTR process. Continuous stirred tank reactor exhibits complex nonlinear operations where reaction is exothermic. It is noticed from literature review that process control of CSTR using neuro-fuzzy systems was attempted by many, but optimal neural network model for identification of CSTR process is not yet available. As CSTR process includes temporal relationship in the input-output mappings, time lagged recurrent neural network is particularly used for identification purpose. The standard back propagation algorithm with momentum term has been proposed in this model. The various parameters like number of processing elements, number of hidden layers, training and testing percentage, learning rule and transfer function in hidden and output layer are investigated on the basis of performance measures like MSE, NMSE, and correlation coefficient on testing data set. Finally effects of different norms are tested along with variation in gamma memory filter. It is demonstrated that dynamic NN model has a remarkable system identification capability for the problems considered in this paper. Thus FTLR NN with gamma memory filter can be used to learn underlying highly nonlinear dynamics of the system, which is a major contribution of this paper.

  5. The 2nd Order Focusing by Energy for TOF Sector Field Mass Analyzer with an Orthogonal Acceleration: Theory, Modeling, Experiment

    Science.gov (United States)

    Poteshin, S. S.; Chernyshev, D. M.; Sysoev, Alexey A.; Sysoev, Alexander A.

    Currently axially symmetric type of analyzer with an electrostatic sector fields (AESF) is rarely used to construct time-of-flight mass spectrometers. The main drawback, hindering the wider use of the analyzers of this type, is the lack of chromatic second-order focusing by energy. However, the configuration of AESF in combination with orthogonal accelerator (OA) allows to achieved it through compensation of energy aberrations of the analyzer in the system of orthogonal input of the ion beam. In the presented work the results of theoretical calculation, simulation and experimentally obtained data are compared. Characteristics of the analyzer with OA in a large extent depend on the parameters of the incoming ion beam. Data of modeling the 2nd stage of gas-dynamic interface, which have the greatest influence on the parameters of the ion beam, is provided.

  6. Effects of human hair on trans-cranial focused ultrasound efficacy in an ex-vivo cadaver model

    Science.gov (United States)

    Hananel, Arik; Snell, John W.; Kassell, Neal F.; Eames, Matthew D. C.

    2012-11-01

    Current practice before a trans-cranial MR guided Focused ultrasound procedure is shaving the patient head on treatment day. Here we present an initial attempt to evaluate the feasibility of trans-cranial FUS, in an unshaved, ex-vivo cadaver skull. We have sonicated using 220kHz and 710kHz head transducers, a cadaver skull filled with tissue mimicking phantom and covered with a wig made of human hair to evaluate feasibility of acoustic energy transfer in a full size model. Heating at focal point was measured using MR proton resonance shift thermometry. Results showed negligible effect of hair in 220kHz, and an 18% drop in temperature elevation when using 710kHz.

  7. The construction of a model of the process of couples' forgiveness in emotion-focused therapy for couples.

    Science.gov (United States)

    Meneses, Catalina Woldarsky; Greenberg, Leslie S

    2011-10-01

    This study explored how forgiveness unfolds in the context of emotion-focused couples therapy (EFT-C) in eight cases of women betrayed by their partners. Forgiveness was defined as a process involving the reduction in negative feelings and the giving out of undeserved compassion. This was measured by changes in the pre- and posttreatment scores on the Enright Forgiveness Inventory, the Unfinished Business Resolution Scale, and a single item directly asking respondents to indicate their degree of forgiveness. A task analysis was performed to rigorously track the steps leading to forgiveness using videotapes of therapy sessions for eight couples. The performance of the four couples who forgave were compared with each other and then contrasted with the performance of another four couples who did not reach forgiveness at the end of therapy. Based on these observations, a model of the process of forgiveness in EFT-C and a process rating system were developed.

  8. Application of a single root-scale model to improve macroscopic modeling of root water uptake: focus on osmotic stress

    Science.gov (United States)

    Jorda, Helena; Perelman, Adi; Lazarovitch, Naftali; Vanderborght, Jan

    2017-04-01

    Root water uptake is a fundamental process in the hydrological cycle and it largely regulates the water balance in the soil vadose zone. Macroscopic stress functions are currently used to estimate the effect of salinity on root water uptake. These functions commonly assume stress to be a function of bulk salinity and of the plant sensitivity to osmotic stress expressed as the salinity at which transpiration is reduced by half or so called tolerance value. However, they fail to integrate additional relevant factors such as atmospheric conditions or root architectural traits. We conducted a comprehensive simulation study on a single root using a 3-D physically-based model that resolves flow and transport to individual root segments and that couples flow in the soil and root system. The effect of salt concentrations on root water uptake was accounted for by including osmotic water potential gradients between the solution at the soil root interface and the root xylem sap in the hydraulic gradient between the soil and root. A large set of factors were studied, namely, potential transpiration rate and dynamics, root length density (RLD), irrigation water quality and irrigation frequency, and leaching fraction. Results were fitted to the macroscopic function developed by van Genuchten and Hoffman (1984) and the dependency of osmotic stress and the fitted macroscopic parameters on the studied factors was evaluated. Osmotic stress was found to be highly dependent on RLD. Low RLDs result in a larger stress to the plant due to high evaporative demand per root length unit. In addition, osmotic stress was positively correlated to potential transpiration rate, and sinusoidal potential transpiration lead to larger stress than when imposed as a constant boundary condition. Macroscopic parameters are usually computed as single values for each crop and used for the entire growing season. However, our study shows that both tolerance value and shape parameter p from the van Genuchten

  9. Social Criticism on Works of Contemporary Women Story Writers

    Directory of Open Access Journals (Sweden)

    Masoomeh Mahmoodi

    2017-08-01

    Full Text Available Goldmann's genetic structuralism approach is one of the literary critique approaches and believes that the literary text are derived from the ideology governing the classes of society, and focuses on study of stories and their structures to know the social structures. A review of the changes made in the themes and subjects of the works of the Iranian story writers that most of them are from the middle class of society, indicates the growth of awareness and understanding of Iranian women about their identity and individuality and the achievement of conditions beyond what they are. Although in popular stories, most Iranian female storytellers are still interested in the reproduction of traditional gender stereotypes, but female storywriters in the field of transcendental literature have entered the changes made in their cognitive realm to the actions of characters of their stories. This reveals that they seek to understand their own self and place in the world around them. Love and loneliness resulted by the confrontation between men and women are a common theme in these works that have been narrated on the various issues arising from the family and social relationships of women.

  10. Pre-clinical in vivo models for the screening of bone biomaterials for oral/craniofacial indications: focus on small-animal models.

    Science.gov (United States)

    Stavropoulos, Andreas; Sculean, Anton; Bosshardt, Dieter D; Buser, Daniel; Klinge, Björn

    2015-06-01

    Preclinical in vivo experimental studies are performed for evaluating proof-of-principle concepts, safety and possible unwanted reactions of candidate bone biomaterials before proceeding to clinical testing. Specifically, models involving small animals have been developed for screening bone biomaterials for their potential to enhance bone formation. No single model can completely recreate the anatomic, physiologic, biomechanic and functional environment of the human mouth and jaws. Relevant aspects regarding physiology, anatomy, dimensions and handling are discussed in this paper to elucidate the advantages and disadvantages of small-animal models. Model selection should be based not on the 'expertise' or capacities of the team, but rather on a scientifically solid rationale, and the animal model selected should reflect the question for which an answer is sought. The rationale for using heterotopic or orthotopic testing sites, and intraosseous, periosseous or extraskeletal defect models, is discussed. The paper also discusses the relevance of critical size defect modeling, with focus on calvarial defects in rodents. In addition, the rabbit sinus model and the capsule model in the rat mandible are presented and discussed in detail. All animal experiments should be designed with care and include sample-size and study-power calculations, thus allowing generation of meaningful data. Moreover, animal experiments are subject to ethical approval by the relevant authority. All procedures and the postoperative handling and care, including postoperative analgesics, should follow best practice.

  11. The effects of safer-sex stories on college students' attitudes toward condoms.

    Science.gov (United States)

    Wright, S S; Kyes, K B

    1996-01-01

    Social learning theory predicts that reading non-erotic stories involving condom use will be as effective as reading erotic stories with condom use in producing positive attitudes toward condoms. Werner's orthogenetic principle, however, predicts that reading erotic condom stories will be most effective because of the link created between sexual arousal and cognitive information about condoms. 168 male and 149 female undergraduates enrolled in Introductory Psychology at a small, private, southern university participated in a study to test the validity of these two theories. The students read one of the following types of stories: erotic with condom placement described, erotic without condom use, or non-erotic with a model for discussing condoms. The men and women who read the non-erotic stories were most positive about condoms and reported the strongest intentions to use condoms in the future. These findings suggest that erotica is not necessary to produce positive attitudes toward condoms.

  12. The Harvard angiogenesis story.

    Science.gov (United States)

    Miller, Joan W

    2014-01-01

    I shall discuss the work of researchers at Harvard Medical School who came together in the early 1990s. Scattered across various Harvard-affiliated hospitals and research centers, these individuals were unified by their interest in ocular neovascularization. Together and separately, they investigated models of ocular neovascularization, exploring tumor angiogenesis in eye development and disease.

  13. Intercultural Collaboration Stories

    DEFF Research Database (Denmark)

    Gertsen, Martine Cardel; Søderberg, Anne-Marie

    2011-01-01

    follows their recognizing new dimensions of their conflicts, eventually furthering their collaboration. We explain how Greimas's actantial model is valuable when mapping differences between and changes in the narrators’ projects, alliances and oppositions in the course of their interaction. Thus, we make...

  14. Without 'Focus'

    Directory of Open Access Journals (Sweden)

    Aldo Sevi

    2010-12-01

    Full Text Available It is widely accepted that a notion of 'focus', more or less as conceived of in Jackendoff (1972, must be incorporated into our theory of grammar, as a means of accounting for certain observed correlations between prosodic facts and semantic/pragmatic facts. In this paper, we put forth the somewhat radical idea that the time has come to give up this customary view, and eliminate 'focus' from our theory of grammar. We argue that such a move is both economical and fruitful.Research over the years has revealed that the correlations between prosody, 'focus', and the alleged semantic/pragmatic effects of focus are much less clear and systematic than we may have initially hoped. First we argue that this state of affairs detracts significantly from the utility of our notion of 'focus', to the point of calling into question the very motivation for including it in the grammar. Then we look at some of the central data, and show how they might be analyzed without recourse to a notion of 'focus'. We concentrate on (i the effect of pitch accent placement on discourse congruence, and (ii the choice of 'associate' for the so-called 'focus sensitive' adverb only. We argue that our focus-free approach to the data improves empirical coverage, and begins to reveal patterns that have previously been obscured by preconceptions about 'focus'.ReferencesBeaver, D. & Clark, B. 2008. Sense and Sensitivity: How Focus Determines Meaning. Blackwell.Beaver, D., Clark, B., Flemming, E., Jaeger, T. F. & Wolters, M. 2007. ‘When semantics meets phonetics: Acoustical studies of second occurrence focus’. Language 83.2: 245–76.http://dx.doi.org/10.1353/lan.2007.0053Beckman, M. & Hirschberg, J. 1994. ‘The ToBI Annotation Conventions’. Ms.,http://www.cs.columbia.edu/~julia/files/conv.pdf.Bolinger, D. 1972. ‘Accent is predictable (if you are a mind-reader’. Language 48.3: 633–44.http://dx.doi.org/10.2307/412039Büring, D. 2006. ‘Focus projection and default

  15. Stories and Interests in Finance

    DEFF Research Database (Denmark)

    Froud, Julie; Nilsson, Adriana; Moran, Michael

    2012-01-01

    The financial crisis can be understood in many different terms. In this article, it is analyzed in terms of the unfolding of a series of elite narratives that shaped the agenda of regulation before the crisis, that were damaged by the crisis, and that were then reframed and recounted again...... in the wake of the crisis. The form of these stories differs in subtle ways by jurisdiction, and thus the fate of postcrisis regulatory practice likewise differs....

  16. Cognitive Processes in Skimming Stories

    Science.gov (United States)

    1979-09-01

    text. Cognitiv Psychology, 1979, 11, 177-220. Bransford, J. D., & Franks, J. J. The abstraction of linguistic ideas. Cognitive Psychology, 1971, 2, 331...Story structure and recall. Cognitiv Psychology, 1977, 30, 111-151. Marcel, T. The effective visual field and the use of ccntext in fast and slow...limited and resource-liml.ted processes. Cognitiv . Psychology, 1975, .7, 44-64. Olb’n, M. R., Harlow, S. D., & Williams, J. D. An evaluation of M

  17. Relating the Story of Things

    Directory of Open Access Journals (Sweden)

    Patricia Allmer

    2011-08-01

    Full Text Available

     

    Abstract: The act and practise of relating is a key element in developing narratives. This essay will explore the interplay and connections between relating and narrating, and the possibilities of producing alternative narratives, independent from hierarchical structures located in linearity, causality and genealogy, by exploring what Gilles Deleuze termed ‘involution,’ as an alternative device of relating. This essay will explore and exemplify this, by focusing on artistic and curatorial strategies of the artist/curators Carson & Miller in the exhibition The Story of Things. This exhibition’s re-organisation of anthropological and ethnographic objects challenges the conventional and traditional representation of such objects in linear and genealogical ways. Curatorial and artistic strategies of display, such as unconventional juxtapositions, slight shifts of the constituent parts of objects, and incongruous combinations of them will be examined. The essay will argue that such strategies are effective in establishing new modes of narrative organisation and new products of combination and juxtaposition.

    Résumé:

     

    L'art et la pratique de lier

  18. Modeling localized delivery of Doxorubicin to the brain following focused ultrasound enhanced blood-brain barrier permeability

    Science.gov (United States)

    Nhan, Tam; Burgess, Alison; Lilge, Lothar; Hynynen, Kullervo

    2014-10-01

    Doxorubicin (Dox) is a well-established chemotherapeutic agent, however it has limited efficacy in treating brain malignancies due to the presence of the blood-brain barrier (BBB). Recent preclinical studies have demonstrated that focused ultrasound induced BBB disruption (BBBD) enables efficient delivery of Dox to the brain. For future treatment planning of BBBD-based drug delivery, it is crucial to establish a mathematical framework to predict the effect of transient BBB permeability enhancement on the spatiotemporal distribution of Dox at the targeted area. The constructed model considers Dox concentrations within three compartments (plasma, extracellular, intracellular) that are governed by various transport processes (e.g. diffusion in interstitial space, exchange across vessel wall, clearance by cerebral spinal fluid, uptake by brain cells). By examining several clinical treatment aspects (e.g. sonication scheme, permeability enhancement, injection mode), our simulation results support the experimental findings of optimal interval delay between two consecutive sonications and therapeutically-sufficient intracellular concentration with respect to transfer constant Ktrans range of 0.01-0.03 min-1. Finally, the model suggests that infusion over a short duration (20-60 min) should be employed along with single-sonication or multiple-sonication at 10 min interval to ensure maximum delivery to the intracellular compartment while attaining minimal cardiotoxicity via suppressing peak plasma concentration.

  19. Community-based implementation of trauma-focused interventions for youth: Economic impact of the learning collaborative model.

    Science.gov (United States)

    Dopp, Alex R; Hanson, Rochelle F; Saunders, Benjamin E; Dismuke, Clara E; Moreland, Angela D

    2017-02-01

    This study investigated the economics of the learning collaborative (LC) model in the implementation of Trauma-Focused Cognitive-Behavioral Therapy (TF-CBT), an evidence-based intervention for traumatic stress in youth. We evaluated the cost-effectiveness of the LC model based on data from 13 LCs completed in the southeastern United States. Specifically, we calculated cost-effectiveness ratios (CERs) for 2 key service outcomes: (a) clinician TF-CBT competence, based on pre- and post-LC self-ratings (n = 574); and (b) trauma-related mental health symptoms (i.e., traumatic stress and depression), self- and caregiver-reported, for youth who received TF-CBT (n = 1,410). CERs represented the cost of achieving 1 standard unit of change on a measure (i.e., d = 1.0). The results indicated that (a) costs of $18,679 per clinician were associated with each unit increase in TF-CBT competency and (b) costs from $5,318 to $6,548 per youth were associated with each unit decrease in mental health symptoms. Thus, although the impact of LC participation on clinician competence did not produce a favorable CER, subsequent reductions in youth psychopathology demonstrated high cost-effectiveness. Clinicians and administrators in community provider agencies should consider these findings in their decisions about implementation of evidence-based interventions for youth with traumatic stress disorders. (PsycINFO Database Record

  20. Shaking table tests and dynamic analyses of masonry wall buildings with flame-shear walls at lower stories

    Institute of Scientific and Technical Information of China (English)

    Xiong Lihong; David Xiong; Wu Ruifeng; Xia Jingqian

    2008-01-01

    This paper describes shaking table tests of three eight-story building models: all are masonry structures in the upper stories, with or without frame-shear walls of one- or two- stories at the bottom. The test results of damage characteristics and seismic responses are provided and compared. Then, nonlinear response analyses are conducted to examine the reliability of the dynamic analysis. Finally, many nonlinear response analyses are performed and it is concluded that for relatively hard sites under a certain lateral stiffness ratio (I.e., the ratio of the stiffness of the lowest upper masonry story to that of the frame-shear wall story), the masonry structure with one-story frame-shear wall at the bottom performs better than a structure built entirely of masonry, and a masonry structure with frame-shear wall of two stories performs better than with one-story frame-shear wall. In relatively soft soil conditions, all three structures have similar performane. In addition, some suggestions that could be helpful for design ofmasomy structures with ground story of frame-shear wall structure in seismic intensity region VII, such as the appropriate lateral stiffness ratio, shear force increase factor of the frame-shear wall story, and permissible maximum height of the building, are proposed.

  1. Another Story of Snow white

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    "白兰氏"杯 2006 广东省中学生英语作文比赛决赛题(初中组)命题作文:你的读者是国际幼儿园的 3- 6 岁的小朋友。实际上, 你的作文是要读给他们听的。内容是鼓励孩子们回家后做一件促进文明保护环境的具体的事。可以包括爱护环境、讲究卫生、节约不浪费资源、爱护小动物、语言和行为文明。文体不限 ( 可以包括倡议书、阐述文、议论文、散文、诗歌、童话等)。自定题目。 My dear children,have you ever heard of the story of Snow White?You are very clever children,I know you must remember the happy ending in the story. The beautiful girl who named Snow White went to live in the palace with her lover. Do you want to know what happend next?listen carefully and I'll tell you the story . It is said ...

  2. Everybody Has a Story III

    DEFF Research Database (Denmark)

    This is the third book in the series “Everybody Has a Story”. The story behind the idea for these books and their title goes back to The Freedom Writers Diary that came about as the result of the teachings of young teacher at a high school in a socially deprived area in Long Beach near Los Angele...... the participating students as these products might be very personal. And personal it has to be, when you become aware of whom you actually are!....... The teacher, Erin Gruwell, found herself more or less forced to base her teachings on the stories of the living conditions of her students. When she became aware of these stories and managed to relate the content of the curriculum to them, her students started to find interest in the subjects of the school...... – and they began to learn. This book is the result of a Freedom Writer course during the spring-semester 2015. During the course the students were faced with different writing exercises as well as hand-on art-making ranging from drawings to photos. The contents of the book are made anonymous to protect...

  3. A (gravitational) toy story

    CERN Document Server

    Barreto, W; Rodriguez-Mueller, B

    2016-01-01

    Usually in computational physics, conclusions about realistic scenarios can be drawn from {\\it ab initio} idealized models. In some ways, the discovery of critical behavior in the gravitational collapse of a massless scalar field leads to the simulation of binary black holes, from its coalescence, to merging and ringdown. We have been lucky enough to have been working on a toy model to explore our way in as these events unfold. We revisited the gravitational instability of a kink problem. During that study, we confirmed a conjecture related to the mass gap, in the context of critical behavior, at the threshold of black hole formation. What is the meaning of this mass gap? Does it have physical relevance? This essay is about these issues.

  4. Digital stories as a tool for health promotion and youth engagement.

    Science.gov (United States)

    Fletcher, Sarah; Mullett, Jennifer

    2016-08-15

    To provide opportunities for intergenerational knowledge sharing for healthy lifestyles; to facilitate youth and Elder mentorship; and to increase the self-esteem of youth by celebrating identity, cultural practices and community connection through the creation and sharing of digital stories. A youth research team (8 youth) aged 13-25, youth participants (60 core participants and 170 workshop participants) and Elders (14) from First Nations communities. The project was conducted with participants from several communities on Vancouver Island through on-site workshops and presentations. Youth and Elders were invited to a 3-day digital story workshop consisting of knowledge-sharing sessions by Elders and digital story training by the youth research team. Workshop attendees returned to their communities to develop stories. The group re-convened at the university to create digital stories focused on community connections, family histories and healthy lifestyles. During the following year the research team delivered instructional sessions in communities on the digital story process. The youth involved reported increased pride in community as well as new or enhanced relationships with Elders. The digital stories method facilitated intergenerational interactions and engaged community members in creating a digital representation of healthy lifestyles. The process itself is an intervention, as it affords critical reflection on historical, cultural and spiritual ideas of health and what it means to be healthy in an Aboriginal community. It is a particularly relevant health promotion tool in First Nations communities with strong oral history traditions.

  5. Determination of tissue thermal conductivity by measuring and modeling temperature rise induced in tissue by pulsed focused ultrasound.

    Directory of Open Access Journals (Sweden)

    Tamara Kujawska

    Full Text Available A tissue thermal conductivity (Ks is an important parameter which knowledge is essential whenever thermal fields induced in selected organs are predicted. The main objective of this study was to develop an alternative ultrasonic method for determining Ks of tissues in vitro suitable for living tissues. First, the method involves measuring of temperature-time T(t rises induced in a tested tissue sample by a pulsed focused ultrasound with measured acoustic properties using thermocouples located on the acoustic beam axis. Measurements were performed for 20-cycle tone bursts with a 2 MHz frequency, 0.2 duty-cycle and 3 different initial pressures corresponding to average acoustic powers equal to 0.7 W, 1.4 W and 2.1 W generated from a circular focused transducer with a diameter of 15 mm and f-number of 1.7 in a two-layer system of media: water/beef liver. Measurement results allowed to determine position of maximum heating located inside the beef liver. It was found that this position is at the same axial distance from the source as the maximum peak-peak pressure calculated for each nonlinear beam produced in the two-layer system of media. Then, the method involves modeling of T(t at the point of maximum heating and fitting it to the experimental data by adjusting Ks. The averaged value of Ks determined by the proposed method was found to be 0.5±0.02 W/(m·°C being in good agreement with values determined by other methods. The proposed method is suitable for determining Ks of some animal tissues in vivo (for example a rat liver.

  6. Dietary Supplementations as Neuroprotective Therapies: Focus on NT-020 Diet Benefits in a Rat Model of Stroke

    Directory of Open Access Journals (Sweden)

    Cesar V. Borlongan

    2012-06-01

    Full Text Available Stroke remains the number one cause of disability in the adult population. Despite scientific progress in our understanding of stroke pathology, only one treatment (tissue plasminogen activator or tPA is able to afford benefits but to less than 3% of ischemic stroke patients. The development of experimental dietary supplement therapeutics designed to stimulate endogenous mechanisms that confer neuroprotection is likely to open new avenues for exploring stroke therapies. The present review article evaluates the recent literature supporting the benefits of dietary supplementation for the therapy of ischemic stroke. This article focuses on discussing the medical benefits of NT-020 as an adjunct agent for stroke therapy. Based on our preliminary data, a pre-stroke treatment with dietary supplementation promotes neuroprotection by decreasing inflammation and enhancing neurogenesis. However, we recognize that a pre-stroke treatment holds weak clinical relevance. Thus, the main goal of this article is to provide information about recent data that support the assumption of natural compounds as neuroprotective and to evaluate the therapeutic effects of a dietary supplement called NT-020 as in a stroke model. We focus on a systematic assessment of practical treatment parameters so that NT-020 and other dietary supplementations can be developed as an adjunct agent for the prevention or treatment of chronic diseases. We offer rationale for determining the optimal dosage, therapeutic window, and mechanism of action of NT-020 as a dietary supplement to produce neuroprotection when administered immediately after stroke onset. We highlight our long-standing principle in championing both translational and basic science approaches in an effort to fully reveal the therapeutic potential of NT-020 as dietary supplementation in the treatment of stroke. We envision dietary supplementation as an adjunct therapy for stroke at acute, subacute, and even chronic periods.

  7. A Capstone Project Using the Gap Analysis Model: Closing the College Readiness Gap for Latino English Language Learners with a Focus on College Affordability and Student Grades

    Science.gov (United States)

    Kurland, Michael A. T.

    2013-01-01

    This capstone dissertation inquiry project focused on the underperformance of English language learners (ELLs) at a high school. The Clark and Estes' (2008) gap analysis model was the analytical framework used to conduct this inquiry. At the request of the school, the inquiry focus was on gaining a better understanding of the underachievement…

  8. Focus expansion and stability of the spread parameter estimate of the power law model for dispersal gradients

    Directory of Open Access Journals (Sweden)

    Peter S. Ojiambo

    2017-06-01

    Full Text Available Empirical and mechanistic modeling indicate that pathogens transmitted via aerially dispersed inoculum follow a power law, resulting in dispersive epidemic waves. The spread parameter (b of the power law model, which is an indicator of the distance of the epidemic wave front from an initial focus per unit time, has been found to be approximately 2 for several animal and plant diseases over a wide range of spatial scales under conditions favorable for disease spread. Although disease spread and epidemic expansion can be influenced by several factors, the stability of the parameter b over multiple epidemic years has not been determined. Additionally, the size of the initial epidemic area is expected to be strongly related to the final epidemic extent for epidemics, but the stability of this relationship is also not well established. Here, empirical data of cucurbit downy mildew epidemics collected from 2008 to 2014 were analyzed using a spatio-temporal model of disease spread that incorporates logistic growth in time with a power law function for dispersal. Final epidemic extent ranged from 4.16 ×108 km2 in 2012 to 6.44 ×108 km2 in 2009. Current epidemic extent became significantly associated (P < 0.0332; 0.56 < R2 < 0.99 with final epidemic area beginning near the end of April, with the association increasing monotonically to 1.0 by the end of the epidemic season in July. The position of the epidemic wave-front became exponentially more distant with time, and epidemic velocity increased linearly with distance. Slopes from the temporal and spatial regression models varied with about a 2.5-fold range across epidemic years. Estimates of b varied substantially ranging from 1.51 to 4.16 across epidemic years. We observed a significant b ×time (or distance interaction (P < 0.05 for epidemic years where data were well described by the power law model. These results suggest that the spread parameter b may not be stable over multiple epidemic

  9. Representing complexity well: a story about teamwork, with implications for how we teach collaboration.

    Science.gov (United States)

    Lingard, Lorelei; McDougall, Allan; Levstik, Mark; Chandok, Natasha; Spafford, Marlee M; Schryer, Catherine

    2012-09-01

    In order to be relevant and impactful, our research into health care teamwork needs to better reflect the complexity inherent to this area. This study explored the complexity of collaborative practice on a distributed transplant team. We employed the theoretical lenses of activity theory to better understand the nature of collaborative complexity and its implications for current approaches to interprofessional collaboration (IPC) and interprofessional education (IPE). Over 4 months, two trained observers conducted 162 hours of observation, 30 field interviews and 17 formal interviews with 39 members of a solid organ transplant team in a Canadian teaching hospital. Participants included consultant medical and surgical staff and postgraduate trainees, the team nurse practitioner, social worker, dietician, pharmacist, physical therapist, bedside nurses, organ donor coordinators and organ recipient coordinators. Data collection and inductive analysis for emergent themes proceeded iteratively. Daily collaborative practice involves improvisation in the face of recurring challenges on a distributed team. This paper focuses on the theme of 'interservice' challenges, which represent instances in which the 'core' transplant team (those providing daily care for transplant patients) work to engage the expertise and resources of other services in the hospital, such as those of radiology and pathology departments. We examine a single story of the core team's collaboration with cardiology, anaesthesiology and radiology services to decide whether a patient is appropriate for transplantation and use this story to consider the team's strategies in the face of conflicting expectations and preferences among these services. This story of collaboration in a distributed team calls into question two premises underpinning current models of IPC and IPE: the notion that stable professional roles exist, and the ideal of a unifying objective of 'caring for the patient'. We suggest important

  10. Migrant life stories and the Web

    DEFF Research Database (Denmark)

    Marselis, Randi

    2013-01-01

    The life stories of migrants are increasingly being told, as part of the work of cultural organizations, and websites are well suited to making such life story projects accessible to the public. However, by using the lives of real people as raw material in a public forum, Web projects raise...... who has openly declared himself an atheist. The article examines his experience of having this somewhat sensitive story made public. The religious aspect inevitably positioned his story in relation to broader political debates about Muslims in Denmark. Since migrants’ stories often touch on highly...... politicized issues, it is crucial that their stories are not co-opted by societal discourses which they do not themselves support....

  11. Re-appraisal and extension of the Gratton-Vargas two-dimensional analytical snowplow model of plasma focus evolution in the context of contemporary research

    CERN Document Server

    Auluck, S K H

    2013-01-01

    Recent resurgence of interest in applications of dense plasma focus and doubts about the conventional view of dense plasma focus as a purely irrotational compressive flow have re-opened questions concerning device optimization. In this context, this paper re-appraises and extends the analytical snowplow model of plasma focus sheath evolution developed by F. Gratton and J.M. Vargas (GV) (Energy Storage, Compression and Switching, Ed. V. Nardi, H. Sahlin, and W. H. Bostick, Eds., vol. 2. New York: Plenum, 1983, p. 353) and shows its relevance to contemporary research. The GV model enables construction of a special orthogonal coordinate system in which the plasma flow problem can be simplified and a model of sheath structure can be formulated. The LPP plasma focus facility, which reports neutron yield better than global scaling law, is shown to be operating closer to an optimum operating point of the GV model as compared with PF-1000.

  12. Start with a Story: Five Schools and a Zoo Use the One Book, One Community Model to Bridge STEM into STEAM

    Science.gov (United States)

    Brock, Patricia; Dunifon, Sarah; Nagel, Lisa

    2016-01-01

    This article outlines an integrated STEAM project based on "The One and Only Ivan" by Katherine Applegate (2012). Elementary students focused on real-world, authentic problems presented in this 2013 Newbery Award-winning novel. The novel deals with difficult issues such as the humane treatment of animals, and has a powerful message of…

  13. Start with a Story: Five Schools and a Zoo Use the One Book, One Community Model to Bridge STEM into STEAM

    Science.gov (United States)

    Brock, Patricia; Dunifon, Sarah; Nagel, Lisa

    2016-01-01

    This article outlines an integrated STEAM project based on "The One and Only Ivan" by Katherine Applegate (2012). Elementary students focused on real-world, authentic problems presented in this 2013 Newbery Award-winning novel. The novel deals with difficult issues such as the humane treatment of animals, and has a powerful message of…

  14. Stories of change in drug treatment

    DEFF Research Database (Denmark)

    Andersen, Ditte

    2015-01-01

    treatment institution shapes how particular stories make sense of the past, present and future; and (4) storytelling in drug treatment is an interactive achievement. A fine-grained analysis illuminates in particular how some stories on gender and drug use are silenced, while others are encouraged....... The demonstration of how local narrative environments shape stories contributes to the general understanding of interactive storytelling in encounters between professionals and clients in treatment settings....

  15. CONTEXTUAL MEANING STUDY OF TRANSLATION OF CHILDRENS STORY THE LION KING FROM ENGLISH INTO INDONESIAN

    Directory of Open Access Journals (Sweden)

    Djuria Suprato

    2010-04-01

    Full Text Available Article aimed to present study on the translation of words, phrases, expressions and sentences in a children's story.The story of "The Lion King" was used as case and content analysis was applied as a reference for the study. The focus of this analysis was aimed to observe the appearance of the terms or meaning of certain words that are considered important and supports the goals of the research, in this case is the translation of words, phrases, sentences in the source language (English into the target language (Indonesian. As its criterion, dictionaries was used and rules of contextual translation was applied. It can be concluded that children's stories emphasize the style and meaning contained in it, so the translation is done must consider the context of the story.

  16. Black Women, Work, Stress, and Perceived Discrimination: The Focused Support Group Model as an Intervention for Stress Reduction

    Science.gov (United States)

    MAYS, VICKIE M.

    2013-01-01

    This exploratory study examined the use of two components (small and large groups) of a community-based intervention, the Focused Support Group (FSG) model, to alleviate employment-related stressors in Black women. Participants were assigned to small groups based on occupational status. Groups met for five weekly 3-hr sessions in didactic or small- and large-group formats. Two evaluations following the didactic session and the small and large group sessions elicited information on satisfaction with each of the formats, self-reported change in stress, awareness of interpersonal and sociopolitical issues affecting Black women in the labor force, assessing support networks, and usefulness of specific discussion topics to stress reduction. Results indicated the usefulness of the small- and large-group formats in reduction of self-reported stress and increases in personal and professional sources of support. Discussions on race and sex discrimination in the workplace were effective in overall stress reduction. The study highlights labor force participation as a potential source of stress for Black women, and supports the development of culture- and gender-appropriate community interventions as viable and cost-effective methods for stress reduction. PMID:9225548

  17. Symbolic Values in Steinbeck's Short Stories

    Institute of Scientific and Technical Information of China (English)

    朱凤英

    2003-01-01

    The essay will analyze the symbols created by Steinbeck and disclose the meaning of the most widely used symbols John Steinbeck resorted toin some of his short stories. These interpretations of the symbols may reveal to readers an utterly different system of values. The author will explore those stories that are relevant from this point of view. This paper will highlight,emphasize and interpret different symbols presented in his stories too. And the author will give a possible way of tackling of Steinbeck short stories.

  18. RE-Powering Success Stories: Green Manufacturing

    Science.gov (United States)

    These success stories discuss sites on formerly contaminated lands, landfills, and mine sites that are manufacturing components for renewable energy, either solar panels, wind turbines, or other components.

  19. Focus: Digital

    DEFF Research Database (Denmark)

    Technology has been an all-important and defining element within the arts throughout the 20th century, and it has fundamentally changed the ways in which we produce and consume music. With this Focus we investigate the latest developments in the digital domain – and their pervasiveness and rapid...... production and reception of contemporary music and sound art. With ‘Digital’ we present four composers' very different answers to how technology impact their work. To Juliana Hodkinson it has become an integral part of her sonic writing. Rudiger Meyer analyses the relationships between art and design and how...

  20. Focusing horn

    CERN Multimedia

    Was used for the AA (antiproton accumulator). Making an antiproton beam took a lot of time and effort. Firstly, protons were accelerated to an energy of 26 GeV in the PS and ejected onto a metal target. From the spray of emerging particles, a magnetic horn picked out 3.6 GeV antiprotons for injection into the AA through a wide-aperture focusing quadrupole magnet.For a million protons hitting the target, just one antiproton was captured, 'cooled' and accumulated. It took 3 days to make a beam of 3 x 10^11 -, three hundred thousand million - antiprotons.