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Sample records for model real-life situations

  1. Rasch modelling of Mathematics and Science teachers’ preferences of real-life situations to be used in Mathematical Literacy

    Directory of Open Access Journals (Sweden)

    Cyril Julie

    2011-10-01

    Full Text Available In order to ascertain the real-life situations that teachers, as stakeholders, would find suitable and appropriate to deal with in Mathematical Literacy (a compulsory subject for students who are not doing Mathematics at the Further Education and Training level of the South African education system, we embarked on a study known as the Relevance of School Mathematics Education (ROSME. The principle underpinning this article is that there are times when it is necessary to assess the functionality and quality of questionnaires used to ascertain affective domain issues. The study provides an analysis technique which is not affected by the sample of individuals completing a questionnaire, provided that the instrument meets particular requirements. It thus improves the rigour of measurement. Various statistics obtained in this study showed that the instrument used to determine the real-life situations which teachers prefer for Mathematical Literacy reasonably identifies this variable. However, it is cautioned that much more care needs to be exercised in construction of such instruments. The results also indicated the real-life situations which teachers most and least preferred to be included in Mathematical Literacy, providing useful information for policy-makers and textbook authors on contextual situations to be included in learning materials.

  2. Real Life Decision Optimization Model

    OpenAIRE

    Raju, Naga; Reddy, Diwakar; Reddy, Rajeswara; Krishnaiah, G

    2016-01-01

    In real life scientific and engineering problems decision making is common practice. Decision making include single decision maker or group of decision makers. Decision maker’s expressions consists imprecise, inconsistent and indeterminate information. Also, the decision maker cannot select the best solution in unidirectional (single goal) way. Therefore, proposed model adopts decision makers’ opinions in Neutrosophic Values (SVNS/INV) which effectively deals imprecise, inconsistent and indet...

  3. Measuring Students' Metacognition in Real-Life Situations

    Science.gov (United States)

    Al-Hilawani, Yasser A.

    2003-01-01

    Metacognitive Performance of four groups of students (hearing high-achieving, hearing average-achieving, hearing underachieving, and deaf and hard of hearing) in first through third grade in the United Arab Emirates was examined and compared. Metacognition was measured using analyses of pictures depicting real-life problematic events, situations,…

  4. Modelling in Action. Examining How Students Approach Modelling Real Life Situations. Three Case Studies. Model of the Movement of an Elevator

    Science.gov (United States)

    Rivas, Eugenia Marmolejo

    2015-01-01

    By means of three case studies, we will present two mathematical modelling activities that are suitable for students enrolled in senior high school and the first year of mathematics at university level. The activities have been designed to enrich the learning process and promote the formation of vital modelling skills. In case studies one and two,…

  5. Modelling in Action. Examining How Students Approach Modelling Real Life Situations. Three Case Studies. Model of the Movement of an Elevator

    Science.gov (United States)

    Rivas, Eugenia Marmolejo

    2015-01-01

    By means of three case studies, we will present two mathematical modelling activities that are suitable for students enrolled in senior high school and the first year of mathematics at university level. The activities have been designed to enrich the learning process and promote the formation of vital modelling skills. In case studies one and two,…

  6. Metacognition in Real Life Situations and Study Skills and Habits: Two Types of Processes

    Science.gov (United States)

    Al-Hilawani, Yasser A.

    2016-01-01

    The relationship between metacognition in real life situations and study skills and habits was examined using a sample of college students. Results showed no significant relationship between these two variables nor was there a significant relationship between study skills and reaction time as measured on the metacognitive test. However, there was…

  7. Projectile motion in real-life situation: Kinematics of basketball shooting

    Science.gov (United States)

    Changjan, A.; Mueanploy, W.

    2015-06-01

    Basketball shooting is a basic practice for players. The path of the ball from the players to the hoop is projectile motion. For undergraduate introductory physics courses student must be taught about projectile motion. Basketball shooting can be used as a case study for learning projectile motion from real-life situation. In this research, we discuss the relationship between optimal angle, minimum initial velocity and the height of the ball before the player shoots the ball for basketball shooting problem analytically. We found that the value of optimal angle and minimum initial velocity decreases with increasing the height of the ball before the player shoots the ball.

  8. Mood effects on memory and executive control in a real-life situation.

    Science.gov (United States)

    Lagner, Prune; Kliegel, Matthias; Phillips, Louise H; Ihle, Andreas; Hering, Alexandra; Ballhausen, Nicola; Schnitzspahn, Katharina M

    2015-01-01

    In the laboratory, studies have shown an inconsistent pattern of whether, and how, mood may affect cognitive functions indicating both mood-related enhancement as well as decline. Surprisingly, little is known about whether there are similar effects in everyday life. Hence, the present study aimed to investigate possible mood effects on memory and executive control in a real-life situation. Mood effects were examined in the context of winning in a sports competition. Sixty-one male handball players were tested with an extensive cognitive test battery (comprising memory and executive control) both after winning a match and after training as neutral baseline. Mood differed significantly between the two testing situations, while physiological arousal and motivation were comparable. Results showed lowered performance after the win compared with training in selected cognitive measures. Specifically, short-term and episodic memory performance was poorer following a win, whereas executive control performance was unaffected by condition. Differences in memory disappeared when emotional states after the match were entered as covariates into the initial analyses. Thus, findings suggest mood-related impairments in memory, but not in executive control processes after a positive real-life event.

  9. Importance of leadership in cardiac arrest situations: from simulation to real life and back.

    Science.gov (United States)

    Hunziker, Sabnina; Tschan, Franziska; Semmer, Norbert K; Marsch, Stephan

    2013-04-18

    The 2010 American Heart Association guidelines now recommend leadership training in Advanced Cardiac Life Support courses. In this review we provide a comprehensive summary of data derived from clinical studies that investigated the importance of leadership in cardiopulmonary resuscitation (CPR). Only a few, mostly observational, studies have been conducted under real-life conditions because of the high heterogeneity of the situations, difficulties in capturing the initial phase of CPR, and ethical issues. Well-controlled studies in the human simulator can fill existing gaps and provide important insights. High-fidelity video-assisted simulator studies from different research groups have shown that a prolonged process of teambuilding is associated with significant shortcomings in CPR, whereas effective leadership improves team performance. In addition, randomised controlled studies have provided evidence that medical students receiving leadership training subsequently showed improved CPR performance, which was sustained after a follow up of 4 months. In addition, leadership is influenced by gender and other factors such as emotional stress. Future studies are needed to investigate cultural differences and how findings from the simulator can be transferred to real-life situations.

  10. On the classification of listening situations and the significance of real-life situations on planning listening exercises

    Institute of Scientific and Technical Information of China (English)

    王丹邱

    2009-01-01

    Understanding foreign speeches is a complex process involving many different skills and abilities,as Ur(1998)cited.In the real world people use different listemng skills for different purposes in different listening situafiom.When teaching listening the teacher should provide various listening materials and design various listening exercises to give the student practice of these skills.This article will firstly talk about the different purposes of real life listening; then,go on to classify the different listening situations whith reference to Ur's (1998) taxonomy.At last the pedagogic implication for the classification is given.

  11. Post-event processing in social anxiety disorder after real-life social situations - An ambulatory assessment study.

    Science.gov (United States)

    Helbig-Lang, Sylvia; von Auer, Maxie; Neubauer, Karolin; Murray, Eileen; Gerlach, Alexander L

    2016-09-01

    Excessive post-mortem processing after social situations, a core symptom of social anxiety disorder (SAD), is thought to contribute to the perpetuation of social anxiety by consolidating negative self-schemata. Empirical findings on actual mechanisms underlying this so-called Post-Event Processing (PEP) are still scarce. The present study sought to identify variables associated with the experience of PEP after real-life social situations in a sample of 49 individuals diagnosed with SAD. Using an ambulatory assessment approach, individuals were asked to report on each distressing social event experienced during one week. A total of 192 events were captured. Hierarchical linear modeling indicated that next to trait social anxiety, the type of social situation (performance vs. interaction situations), self-focused attention, safety behavior use, and negative affect predicted levels of PEP after social situations. These findings add to the growing literature that emphasizes the importance of situational factors for the experience of PEP, and highlight potential venues to prevent it.

  12. Thai nursing students' experiences when attending real life situations involving cardiac life support: A Phenomenological study.

    Science.gov (United States)

    Matchim, Yaowarat; Kongsuwan, Waraporn

    2015-12-01

    During the last few years, manikin simulations have been used for cardiac life support training procedures in medical and nursing education. However, some nursing students have experienced attending real events involving cardiac life support during their clinical practice. This study aims to describe the meaning of experience of Thai nursing students when attending real situations of cardiac life support. A hermeneutic phenomenological study was used. Third and fourth year bachelor of nursing students at a university in the southern region of Thailand who had the experience of attending real situation of cardiac life support were purposely selected as the informants. The data were generated from individual in-depth interviews with eighteen nursing students. Van Manen's approach was used to analyze the data. Trustworthiness was established using the criteria set out by Lincoln and Guba. Essential themes situated in the context of the four existential grounds of body, time, space, and relation emerged. These were: being worried and fearful while desiring to participate in cardiac life support procedures; enhancing self value; knowing each moment is meaningful for one's life; having time to understand the reality of life; being in a small corner; appreciating such opportunities and the encouragement given by nurses and the healthcare team; and feeling empathy. Besides learning in classrooms and practicing in labs, experiencing real situations is beneficial for nursing students in learning cardiac life support. This study provides information that can be used for clinical teaching management in the topics relating to cardiac life support. Copyright © 2015 Elsevier Ltd. All rights reserved.

  13. Comparing a Real-Life WSN Platform Small Network and its OPNET Modeler Model using Hypothesis Testing

    Directory of Open Access Journals (Sweden)

    Gilbert E. Pérez

    2014-12-01

    Full Text Available To avoid the high cost and arduous effort usually associated with field analysis of Wireless Sensor Network (WSN, Modeling and Simulation (M&S is used to predict the behavior and performance of the network. However, the simulation models utilized to imitate real life networks are often used for general purpose. Therefore, they are less likely to provide accurate predictions for different real life networks. In this paper, a comparison methodology based on hypothesis testing is proposed to evaluate and compare simulation output versus real-life network measurements. Performance related parameters such as traffic generation rates and goodput rates for a small WSN are considered. To execute the comparison methodology, a "Comparison Tool", composed of MATLAB scripts is developed and used. The comparison tool demonstrates the need for model verification and the analysis of good agreements between the simulation and empirical measurements.

  14. Comparative analysis for traffic flow forecasting models with real-life data in Beijing

    Directory of Open Access Journals (Sweden)

    Yaping Rong

    2015-12-01

    Full Text Available Rational traffic flow forecasting is essential to the development of advanced intelligent transportation systems. Most existing research focuses on methodologies to improve prediction accuracy. However, applications of different forecast models have not been adequately studied yet. This research compares the performance of three representative prediction models with real-life data in Beijing. They are autoregressive integrated moving average, neutral network, and nonparametric regression. The results suggest that nonparametric regression significantly outperforms the other models. With Wilcoxon signed-rank test, the root mean square errors and the error distribution reveal that the nonparametric regression model experiences superior accuracy. In addition, the nonparametric regression model exhibits the best spatial-transferred application effect.

  15. Issues of Application of Machine Learning Models for Virtual and Real-Life Buildings

    Directory of Open Access Journals (Sweden)

    Young Min Kim

    2016-06-01

    Full Text Available The current Building Energy Performance Simulation (BEPS tools are based on first principles. For the correct use of BEPS tools, simulationists should have an in-depth understanding of building physics, numerical methods, control logics of building systems, etc. However, it takes significant time and effort to develop a first principles-based simulation model for existing buildings—mainly due to the laborious process of data gathering, uncertain inputs, model calibration, etc. Rather than resorting to an expert’s effort, a data-driven approach (so-called “inverse” approach has received growing attention for the simulation of existing buildings. This paper reports a cross-comparison of three popular machine learning models (Artificial Neural Network (ANN, Support Vector Machine (SVM, and Gaussian Process (GP for predicting a chiller’s energy consumption in a virtual and a real-life building. The predictions based on the three models are sufficiently accurate compared to the virtual and real measurements. This paper addresses the following issues for the successful development of machine learning models: reproducibility, selection of inputs, training period, outlying data obtained from the building energy management system (BEMS, and validation of the models. From the result of this comparative study, it was found that SVM has a disadvantage in computation time compared to ANN and GP. GP is the most sensitive to a training period among the three models.

  16. Physiologically based pharmacokinetic toolkit to evaluate environmental exposures: Applications of the dioxin model to study real life exposures.

    Science.gov (United States)

    Emond, Claude; Ruiz, Patricia; Mumtaz, Moiz

    2017-01-15

    Chlorinated dibenzo-p-dioxins (CDDs) are a series of mono- to octa-chlorinated homologous chemicals commonly referred to as polychlorinated dioxins. One of the most potent, well-known, and persistent member of this family is 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). As part of translational research to make computerized models accessible to health risk assessors, we present a Berkeley Madonna recoded version of the human physiologically based pharmacokinetic (PBPK) model used by the U.S. Environmental Protection Agency (EPA) in the recent dioxin assessment. This model incorporates CYP1A2 induction, which is an important metabolic vector that drives dioxin distribution in the human body, and it uses a variable elimination half-life that is body burden dependent. To evaluate the model accuracy, the recoded model predictions were compared with those of the original published model. The simulations performed with the recoded model matched well with those of the original model. The recoded model was then applied to available data sets of real life exposure studies. The recoded model can describe acute and chronic exposures and can be useful for interpreting human biomonitoring data as part of an overall dioxin and/or dioxin-like compounds risk assessment. Copyright © 2016. Published by Elsevier Inc.

  17. A Situational Maintenance Model

    DEFF Research Database (Denmark)

    Luxhoj, James T.; Thorsteinsson, Uffe; Riis, Jens Ove

    1997-01-01

    An overview of trend in maintenance management and presentation of a situational model and an analytical tools for identification of managerial efforts in maintenance.......An overview of trend in maintenance management and presentation of a situational model and an analytical tools for identification of managerial efforts in maintenance....

  18. A Situational Maintenance Model

    DEFF Research Database (Denmark)

    Luxhoj, James T.; Thorsteinsson, Uffe; Riis, Jens Ove

    1997-01-01

    An overview of trend in maintenance management and presentation of a situational model and an analytical tools for identification of managerial efforts in maintenance.......An overview of trend in maintenance management and presentation of a situational model and an analytical tools for identification of managerial efforts in maintenance....

  19. Modelling of domestic refrigerators' energy consumption under real life conditions in Europe

    Energy Technology Data Exchange (ETDEWEB)

    Geppert, Jasmin

    2011-05-23

    In recent decades, energy and resource savings have become increasingly important, not only in the industrial, but also the residential sector. As one of the largest energy users in private homes, domestic refrigerators and freezers were among the first appliances to be targeted for energy efficiency improvements. With the aim of encouraging manufacturers to develop and produce more efficient appliances, the European Energy Label was introduced in the mid-nineties. However, the energy use of refrigerators does not only depend on technical components and features. Especially the using conditions in private homes are of a decisive influence. Thus, the present study has been conducted to test the sensitivity of refrigerators' energy consumption to various usage conditions within realistic ranges, which have been determined by means of two empirical studies. Key information gathered from the experiments were used as a base for the development and validation of a simplified model that allows predicting the energy consumption of refrigerators in use. The practical experiments were performed under controlled laboratory conditions with four different refrigerators with an A{sup +} or A{sup ++} energy efficiency rating (two statically cooled built-in fridge-freezers, one dynamically cooled refrigerator and one statically cooled refrigerator). The investigations revealed that the ambient temperature has the greatest impact on a refrigerator's energy consumption, followed by thermostat setting and heat load by insertion of warm items. The refrigerators' load under static conditions as well as the number of door openings have almost no impact on energy consumption. The modelling methodology follows a first-principle approach adjusted by experimental data. When compared to experimental results, model predictions show a reasonable agreement for the whole range of investigated conditions. (orig.)

  20. Development and validation of a generic finite element vehicle buck model for the analysis of driver rib fractures in real life nearside oblique frontal crashes.

    Science.gov (United States)

    Iraeus, Johan; Lindquist, Mats

    2016-10-01

    Frontal crashes still account for approximately half of all fatalities in passenger cars, despite several decades of crash-related research. For serious injuries in this crash mode, several authors have listed the thorax as the most important. Computer simulation provides an effective tool to study crashes and evaluate injury mechanisms, and using stochastic input data, whole populations of crashes can be studied. The aim of this study was to develop a generic buck model and to validate this model on a population of real-life frontal crashes in terms of the risk of rib fracture. The study was conducted in four phases. In the first phase, real-life validation data were derived by analyzing NASS/CDS data to find the relationship between injury risk and crash parameters. In addition, available statistical distributions for the parameters were collected. In the second phase, a generic parameterized finite element (FE) model of a vehicle interior was developed based on laser scans from the A2MAC1 database. In the third phase, model parameters that could not be found in the literature were estimated using reverse engineering based on NCAP tests. Finally, in the fourth phase, the stochastic FE model was used to simulate a population of real-life crashes, and the result was compared to the validation data from phase one. The stochastic FE simulation model overestimates the risk of rib fracture, more for young occupants and less for senior occupants. However, if the effect of underestimation of rib fractures in the NASS/CDS material is accounted for using statistical simulations, the risk of rib fracture based on the stochastic FE model matches the risk based on the NASS/CDS data for senior occupants. The current version of the stochastic model can be used to evaluate new safety measures using a population of frontal crashes for senior occupants. Copyright © 2016 Elsevier Ltd. All rights reserved.

  1. Situational Behavior Modeling

    Science.gov (United States)

    2009-06-30

    von Mises [27] in 1949 and Bunge [28] in the 1970s. However, the earliest formal notion of situation (although not situation awareness) was introduced...Action: A Treatise on Economics. Fox & Wilkes, 1997. 28 M. Bunge . Treatise on basic philosophy. III: Ontology: The furniture of the world. Reidel

  2. Advances in inline quantification of co-eluting proteins in chromatography: Process-data-based model calibration and application towards real-life separation issues.

    Science.gov (United States)

    Brestrich, Nina; Sanden, Adrian; Kraft, Axel; McCann, Karl; Bertolini, Joseph; Hubbuch, Jürgen

    2015-07-01

    Pooling decisions in preparative liquid chromatography for protein purification are usually based on univariate UV absorption measurements that are not able to differentiate between product and co-eluting contaminants. This can result in inconsistent pool purities or yields, if there is a batch-to-batch variability of the feedstock. To overcome this analytical bottleneck, a tool for selective inline quantification of co-eluting model proteins using mid-UV absorption spectra and Partial Least Squares Regression (PLS) was presented in a previous study and applied for real-time pooling decisions. In this paper, a process-data-based method for the PLS model calibration will be introduced that allows the application of the tool towards chromatography steps of real-life processes. The process-data-based calibration method uses recorded inline mid-UV absorption spectra that are correlated with offline fraction analytics to calibrate PLS models. In order to generate average spectra from the inline data, a Visual Basic for Application macro was successfully developed. The process-data-based model calibration was established using a ternary model protein system. Afterwards, it was successfully demonstrated in two case studies that the calibration method is applicable towards real-life separation issues. The calibrated PLS models allowed a successful quantification of the co-eluting species in a cation-exchange-based aggregate and fraction removal during the purification of monoclonal antibodies and of co-eluting serum proteins in an anion-exchange-based purification of Cohn supernatant I. Consequently, the presented process-data-based PLS model calibration in combination with the tool for selective inline quantification has a great potential for the monitoring of future chromatography steps and may contribute to manage batch-to-batch variability by real-time pooling decisions.

  3. A comparison of breath- and blood-alcohol test results from real-life policing situations: a one-year study of data from the Central Hessian police district in Germany.

    Science.gov (United States)

    Roiu, Immanuel; Birngruber, Christoph G; Spencer, Victoria C; Wollersen, Heike; Dettmeyer, Reinhard; Verhoff, Marcel A

    2013-10-10

    So far, studies investigating the comparability of breath alcohol concentration (BrAC) with blood alcohol concentration (BAC) have focused on the accuracy of BrAC testing instruments. The presented study, conducted with cases from the district of the Middle Hessian Police Headquarters, is to the best of our knowledge the first to compare both methods under real-life conditions in normal policing situations. For a 1-year period, alcohol-impaired drunk-driving suspects, who were by criminal procedure required to give a blood sample, were offered a voluntary, additional BrAC test with a "Dräger Alcotest 7110 Evidential". The BrAC test was to be administered as soon as possible after the suspect had been apprehended, without, however, delaying the collection of the blood sample. Ninety-two cases could be included in our study. In 30 cases, a blood sample was not taken; in 11 cases, a BrAC test could not be performed. In the remaining 51 cases, we found the following pairings of BrAC and BAC results: BrAC≥0.55 mg/l and BAC≥1.1‰ (n=39); 0.25 mg/l≤BrAC<0.55 mg/l and 0.5‰≤BAC<1.1‰ (n=5); BrAC≥0.55 mg/l and BAC<1.1‰ (n=4); BrAC<0.55 mg/l and BAC≥1.1‰ (n=3). The mean value for the conversion factor, Q, was 2.12‰l/mg. In accord with numerous other studies, our study results would suggest a value of 2.1‰ l/mg to German legislature as a new statutory value for Q. In borderline cases, of which there were already 7 in our study with 51 cases, suspects could benefit both from a BrAC test or a BAC test, with the benefit lastly depending more on early testing time than on the test method used. Our results support the call for the earliest possible measurement of alcohol concentration values after a drunk driving offense was committed. In some situations, this can probably only be accomplished with BrAC testing. A supplementary blood sample and BAC testing could compensate for the known weaknesses of BrAC testing. Thus, the complementary use of both methods

  4. Use of fatal real-life crashes to analyze a safe road transport system model, including the road user, the vehicle, and the road.

    Science.gov (United States)

    Stigson, Helena; Krafft, Maria; Tingvall, Claes

    2008-10-01

    To evaluate if the Swedish Road Administration (SRA) model for a safe road transport system, which includes the interaction between the road user, the vehicle, and the road, could be used to classify fatal car crashes according to some safety indicators. Also, to present a development of the model to better identify system weakness. Real-life crashes with a fatal outcome were classified according to the vehicle's safety rating by Euro NCAP (European Road Assessment Programme) and fitment of ESC (Electronic Stability Control). For each crash, the road was also classified according to EuroRAP (European Road Assessment Programme) criteria, and human behavior in terms of speeding, seat belt use, and driving under the influence of alcohol. Each crash was compared with the model criteria, to identify components that might have contributed to fatal outcome. All fatal crashes where a car occupant was killed that occurred in Sweden during 2004 were included: in all, 215 crashes with 248 fatalities. The data were collected from the in-depth fatal crash data of the Swedish Road Administration (SRA). It was possible to classify 93% of the fatal car crashes according to the SRA model. A number of shortcomings in the criteria were identified since the model did not address rear-end or animal collisions or collisions with stationary/parked vehicles or trailers (18 out of 248 cases). Using the further developed model, it was possible to identify that most of the crashes occurred when two or all three components interacted (in 85 of the total 230 cases). Noncompliance with safety criteria for the road user, the vehicle, and the road led to fatal outcome in 43, 27, and 75 cases, respectively. The SRA model was found to be useful for classifying fatal crashes but needs to be further developed to identify how the components interact and thereby identify weaknesses in the road traffic system. This developed model might be a tool to systematically identify which of the components are

  5. Operation of ULCS - real life

    Directory of Open Access Journals (Sweden)

    Jasna Prpić-Oršić

    2014-12-01

    Full Text Available In this paper the real life operation of ULCS (Ultra Large Container Ships is presented from the point of view of shipmasters. The paper provides interpretation of results of questionnaire filled by masters of large container ships during Tools for Ultra Large Container Ships (TULC EUI FP7 project. This is done in a way that results of questionnaire are further reviewed and commented by experienced master of ULCS. Following phenomena are subject of questionnaire and further discussed in the paper: parametric rolling, slamming, whipping, springing, green water and rogue waves. Special attention is given to the definition of rough sea states as well as to measures that ship masters take to avoid them as well as to the manoeuvring in heavy seas. The role of the wave forecast and weather routing software is also discussed.

  6. Computer Simulation as a Tool for Analyzing and Optimizing Real-Life Processes

    Directory of Open Access Journals (Sweden)

    Tomáš Domonkos

    2010-06-01

    Full Text Available In some real-life situations, the analysis of complicated systems using standard analytical methods of operational research represents a particularly difficult endeavor, due to the system's complicated structure or the impossibility of reaching a mathematical solution. In cases when we are not able to use the standard methods of operational research, we can use simulation modeling. Sometimes simulation modeling as a tool for supporting practical decision-making offers a possible solution for this problem. The aim of this paper is to characterize briefly the development of discrete-event simulation methodology over the past 50 years on the grounds of the evolution of various simulation programs, describe the essentials of the simulation program tool Simul8 and present, on the basis of a case study, how we can analyze and optimize complicated real-life systems.

  7. Real-life applications with membrane computing

    CERN Document Server

    Zhang, Gexiang; Gheorghe, Marian

    2017-01-01

    This book thoroughly investigates the underlying theoretical basis of membrane computing models, and reveals their latest applications. In addition, to date there have been no illustrative case studies or complex real-life applications that capitalize on the full potential of the sophisticated membrane systems computational apparatus; gaps that this book remedies. By studying various complex applications – including engineering optimization, power systems fault diagnosis, mobile robot controller design, and complex biological systems involving data modeling and process interactions – the book also extends the capabilities of membrane systems models with features such as formal verification techniques, evolutionary approaches, and fuzzy reasoning methods. As such, the book offers a comprehensive and up-to-date guide for all researchers, PhDs and undergraduate students in the fields of computer science, engineering and the bio-sciences who are interested in the applications of natural computing models.

  8. [Real life simulations to train nurses].

    Science.gov (United States)

    Alonso Felpete, Alberto Jesús; Abajas Bustillo, Rebeca; De la Horra Gutiérrez, Inmaculada; Hoz Cuerno, Verónica; Llata Agüero, Gema; López López, Luis Mariano; Sánchez Herrán, Beatriz

    2004-01-01

    Nurses must confront critical potential life threatening situations daily. These are very tense situations which must be solved in a rapid, adequate manner in coordination with the rest of the professional health team. How to deal with these crises, which usually follow an established protocol, must be learned and practiced in a safe environment which provides the greatest possible guarantee of success. The best way to acquire this knowledge and skill is through a real life simulation. Nurses from various disciplines carry out their work in the Training Center for Critical Crises at the Marqués de Valdecilla University Hospital in Santander, the only center in Spain which runs this type of simulation. In 2003, this center initiated a specific training simulation for nurses whose purpose is to increase scientific-technical knowledge to the maximum and accelerate the learning of non-technical social and cognitive fundamentals within the working environment of a professional health team. The following article describes a simulation meeting these characteristics, its teaching methods, advantages, importance for professional health teams, and its repercussions on patients.

  9. Can virtual reality exposure therapy gains be generalized to real life? A meta-analysis of studies applying behavioral assessments

    NARCIS (Netherlands)

    Morina, N.; Ijntema, H.; Meyerbröker, K.; Emmelkamp, P.M.G.

    2015-01-01

    In virtual reality exposure therapy (VRET), patients are exposed to virtual environments that resemble feared real-life situations. The aim of the current study was to assess the extent to which VRET gains can be observed in real-life situations. We conducted a meta-analysis of clinical trials apply

  10. Learning situation models in a smart home.

    Science.gov (United States)

    Brdiczka, Oliver; Crowley, James L; Reignier, Patrick

    2009-02-01

    This paper addresses the problem of learning situation models for providing context-aware services. Context for modeling human behavior in a smart environment is represented by a situation model describing environment, users, and their activities. A framework for acquiring and evolving different layers of a situation model in a smart environment is proposed. Different learning methods are presented as part of this framework: role detection per entity, unsupervised extraction of situations from multimodal data, supervised learning of situation representations, and evolution of a predefined situation model with feedback. The situation model serves as frame and support for the different methods, permitting to stay in an intuitive declarative framework. The proposed methods have been integrated into a whole system for smart home environment. The implementation is detailed, and two evaluations are conducted in the smart home environment. The obtained results validate the proposed approach.

  11. Endangered Species: Real Life in Two Dimensions

    Science.gov (United States)

    Henderson, Lynette K.

    2012-01-01

    The focus of "Endangered Species: Real Life in Two Dimensions" is to create awareness about a critical environmental issue. There is a special urgency to this project because large numbers of animal species are currently endangered or on the brink of extinction. In addition to being enlightened about this important topic through research, students…

  12. Scaffolding in Complex Modelling Situations

    Science.gov (United States)

    Stender, Peter; Kaiser, Gabriele

    2015-01-01

    The implementation of teacher-independent realistic modelling processes is an ambitious educational activity with many unsolved problems so far. Amongst others, there hardly exists any empirical knowledge about efficient ways of possible teacher support with students' activities, which should be mainly independent from the teacher. The research…

  13. A Situated Model of Creative Learning

    National Research Council Canada - National Science Library

    Tanggaard, Lene

    2014-01-01

    This article puts forward a situated model of creative learning. Most educational studies on creativity tend to concentrate on explaining the relation between teaching and creativity while keeping learning as a secondary concept...

  14. A scalable model for network situational awareness based on Endsley's situation model

    Institute of Scientific and Technical Information of China (English)

    Hu Wei; Li Jianhua; Chen Xiuzhen; Jiang Xinghao; Zuo Min

    2007-01-01

    The paper introduces the Endsley's situation model into network security to describe the network security situation,and improves Endsley'S data processing to suit network alerts.The proposet model contains the information of incident frequency.incident time and incident space.The HoneyNet dataset is selected to evaluate the proposed model in the evaluation.The paper pmposes three definitions to depict and predigest the whole situation extraction in detail.and a fusion component to reduce the influence of alert redundancy on the total security situation.The less complex extraction makes the situation analysismore efficient,and the fine-grained model makes the analysis have a better expansibility.Finally,the situational variation curves are simulated,and the evaluation results prove the situation model applicable and efficient.

  15. Faculty Development Using the Situational Leadership Model.

    Science.gov (United States)

    Shaner, Michael C.

    1995-01-01

    The situational leadership model developed by Hersey and Blanchard is described, and the task-specific model is then applied to the four primary tasks of college faculty--teaching, research, community service, and institutional service. The model combines directive and supportive behavior as they are reflected in four distinctive leadership…

  16. Carbohydrates and exercise performance in non-fasted athletes: A systematic review of studies mimicking real-life

    OpenAIRE

    Colombani Paolo C; Mannhart Christof; Mettler Samuel

    2013-01-01

    Abstract There is a consensus claiming an ergogenic effect of carbohydrates ingested in the proximity of or during a performance bout. However, in performance studies, the protocols that are used are often highly standardized (e.g. fasted subjects, constant exercise intensity with time-to-exhaustion tests), and do not necessarily reflect competitive real-life situations. Therefore, we aimed at systematically summarizing all studies with a setting mimicking the situation of a real-life competi...

  17. System dynamics modelling of situation awareness

    CSIR Research Space (South Africa)

    Oosthuizen, R

    2015-11-01

    Full Text Available . The feedback loops and delays in the Command and Control system also contribute to the complex dynamic behavior. This paper will build on existing situation awareness models to develop a System Dynamics model to support a qualitative investigation through...

  18. A improved Network Security Situation Awareness Model

    Directory of Open Access Journals (Sweden)

    Li Fangwei

    2015-08-01

    Full Text Available In order to reflect the situation of network security assessment performance fully and accurately, a new network security situation awareness model based on information fusion was proposed. Network security situation is the result of fusion three aspects evaluation. In terms of attack, to improve the accuracy of evaluation, a situation assessment method of DDoS attack based on the information of data packet was proposed. In terms of vulnerability, a improved Common Vulnerability Scoring System (CVSS was raised and maked the assessment more comprehensive. In terms of node weights, the method of calculating the combined weights and optimizing the result by Sequence Quadratic Program (SQP algorithm which reduced the uncertainty of fusion was raised. To verify the validity and necessity of the method, a testing platform was built and used to test through evaluating 2000 DAPRA data sets. Experiments show that the method can improve the accuracy of evaluation results.

  19. Can virtual reality exposure therapy gains be generalized to real-life? : A meta-analysis of studies applying behavioral assessments

    NARCIS (Netherlands)

    Morina, Nexhmedin; Ijntema, Hiske; Meyerbröker, Katharina; Emmelkamp, Paul M G

    2015-01-01

    In virtual reality exposure therapy (VRET), patients are exposed to virtual environments that resemble feared real-life situations. The aim of the current study was to assess the extent to which VRET gains can be observed in real-life situations. We conducted a meta-analysis of clinical trials apply

  20. A situated model of creative learning

    DEFF Research Database (Denmark)

    Tanggaard, Lene

    2014-01-01

    This article puts forward a situated model of creative learning. Most educational studies on creativity tend to concentrate on explaining the relation between teaching and creativity while keeping learning as a secondary concept. However, it has been stated that it is likely that teaching...... creatively leads to creative learning, suggesting that there is a need to describe the concept of creative learning and to analyse its possible constituents. Accordingly, this presentation introduces an empirically based and theoretically informed model of a creative learning community. The model is based...... of interest. As a theoretical point of departure, this presentation will outline a situated model of creativity and learning, and following this, will introduce a model of creative learning. This presentation will include several empirical examples. In the final part, the model will be discussed in relation...

  1. A Situated Model of Creative Learning

    Science.gov (United States)

    Tanggaard, Lene

    2014-01-01

    This article puts forward a situated model of creative learning. Most educational studies on creativity tend to concentrate on explaining the relation between teaching and creativity while keeping learning as a secondary concept. However, it has been stated that it is likely that teaching creatively leads to creative learning, suggesting that…

  2. Modelling remediation options for urban contamination situations

    DEFF Research Database (Denmark)

    Thiessen, K.M.; Andersson, Kasper Grann; Charnock, T.W.

    2009-01-01

    The impact on a population from an event resulting in dispersal and deposition of radionuclides in an urban area could be significant, in terms of both the number of people affected and the economic costs of recovery. The use of computer models for assessment of urban contamination situations...

  3. A Situated Model of Creative Learning

    Science.gov (United States)

    Tanggaard, Lene

    2014-01-01

    This article puts forward a situated model of creative learning. Most educational studies on creativity tend to concentrate on explaining the relation between teaching and creativity while keeping learning as a secondary concept. However, it has been stated that it is likely that teaching creatively leads to creative learning, suggesting that…

  4. Real-Life Challenges in Using Augmentative and Alternative Communication by Persons with Amyotrophic Lateral Sclerosis

    Science.gov (United States)

    Ray, Jayanti

    2015-01-01

    Given the linguistic and cognitive demands of communication, adult Augmentative and Alternative Communication (AAC) users with acquired communication disorders may have difficulty using AAC systems consistently and effectively in "real-life" situations. The process of recommending AAC systems and strategies is an area of exploration,…

  5. Real-Life Challenges in Using Augmentative and Alternative Communication by Persons with Amyotrophic Lateral Sclerosis

    Science.gov (United States)

    Ray, Jayanti

    2015-01-01

    Given the linguistic and cognitive demands of communication, adult Augmentative and Alternative Communication (AAC) users with acquired communication disorders may have difficulty using AAC systems consistently and effectively in "real-life" situations. The process of recommending AAC systems and strategies is an area of exploration,…

  6. A Real-Life Case Study of Audit Interactions--Resolving Messy, Complex Problems

    Science.gov (United States)

    Beattie, Vivien; Fearnley, Stella; Hines, Tony

    2012-01-01

    Real-life accounting and auditing problems are often complex and messy, requiring the synthesis of technical knowledge in addition to the application of generic skills. To help students acquire the necessary skills to deal with these problems effectively, educators have called for the use of case-based methods. Cases based on real situations (such…

  7. Moral Emotions and Moral Judgments in Children's Narratives: Comparing Real-Life and Hypothetical Transgressions

    Science.gov (United States)

    Gutzwiller-Helfenfinger, Eveline; Gasser, Luciano; Malti, Tina

    2010-01-01

    How children make meaning of their own social experiences in situations involving moral issues is central to their subsequent affective and cognitive moral learning. Our study of young children's narratives describing their interpersonal conflicts shows that the emotions and judgments constructed in the course of these real-life narratives differ…

  8. Modeling Control Situations in Power System Operations

    DEFF Research Database (Denmark)

    Saleem, Arshad; Lind, Morten; Singh, Sri Niwas

    2010-01-01

    Increased interconnection and loading of the power system along with deregulation has brought new challenges for electric power system operation, control and automation. Traditional power system models used in intelligent operation and control are highly dependent on the task purpose. Thus, a model...... for intelligent operation and control must represent system features, so that information from measurements can be related to possible system states and to control actions. These general modeling requirements are well understood, but it is, in general, difficult to translate them into a model because of the lack...... of explicit principles for model construction. This paper presents a work on using explicit means-ends model based reasoning about complex control situations which results in maintaining consistent perspectives and selecting appropriate control action for goal driven agents. An example of power system...

  9. Modeling Control Situations in Power System Operations

    DEFF Research Database (Denmark)

    Saleem, Arshad; Lind, Morten; Singh, Sri Niwas

    2010-01-01

    Increased interconnection and loading of the power system along with deregulation has brought new challenges for electric power system operation, control and automation. Traditional power system models used in intelligent operation and control are highly dependent on the task purpose. Thus, a model...... for intelligent operation and control must represent system features, so that information from measurements can be related to possible system states and to control actions. These general modeling requirements are well understood, but it is, in general, difficult to translate them into a model because of the lack...... of explicit principles for model construction. This paper presents a work on using explicit means-ends model based reasoning about complex control situations which results in maintaining consistent perspectives and selecting appropriate control action for goal driven agents. An example of power system...

  10. Dangerous situations in a synchronized flow model

    Science.gov (United States)

    Jiang, Rui; Wu, Qing-Song

    2007-04-01

    This paper studies the dangerous situation (DS) in a synchronized flow model. The DS on the two branches of the fundamental diagram are investigated, respectively. It is shown that different relationship between DS probability and the density exists in the synchronized flow and in the jams. Moreover, we prove that there is no DS caused by non-stopped car although the model itself is a non-exclusion process. We classify the DS into four sub-types and study the probability of these four sub-types. The simulation result is consistent with the real traffic.

  11. How Accumulated Real Life Stress Experience and Cognitive Speed Interact on Decision-Making Processes.

    Science.gov (United States)

    Friedel, Eva; Sebold, Miriam; Kuitunen-Paul, Sören; Nebe, Stephan; Veer, Ilya M; Zimmermann, Ulrich S; Schlagenhauf, Florian; Smolka, Michael N; Rapp, Michael; Walter, Henrik; Heinz, Andreas

    2017-01-01

    Rationale: Advances in neurocomputational modeling suggest that valuation systems for goal-directed (deliberative) on one side, and habitual (automatic) decision-making on the other side may rely on distinct computational strategies for reinforcement learning, namely model-free vs. model-based learning. As a key theoretical difference, the model-based system strongly demands cognitive functions to plan actions prospectively based on an internal cognitive model of the environment, whereas valuation in the model-free system relies on rather simple learning rules from operant conditioning to retrospectively associate actions with their outcomes and is thus cognitively less demanding. Acute stress reactivity is known to impair model-based but not model-free choice behavior, with higher working memory capacity protecting the model-based system from acute stress. However, it is not clear which impact accumulated real life stress has on model-free and model-based decision systems and how this influence interacts with cognitive abilities. Methods: We used a sequential decision-making task distinguishing relative contributions of both learning strategies to choice behavior, the Social Readjustment Rating Scale questionnaire to assess accumulated real life stress, and the Digit Symbol Substitution Test to test cognitive speed in 95 healthy subjects. Results: Individuals reporting high stress exposure who had low cognitive speed showed reduced model-based but increased model-free behavioral control. In contrast, subjects exposed to accumulated real life stress with high cognitive speed displayed increased model-based performance but reduced model-free control. Conclusion: These findings suggest that accumulated real life stress exposure can enhance reliance on cognitive speed for model-based computations, which may ultimately protect the model-based system from the detrimental influences of accumulated real life stress. The combination of accumulated real life stress exposure

  12. Lantus solostar in real life medical practice

    Directory of Open Access Journals (Sweden)

    Florenţiu Ariel

    2014-03-01

    Full Text Available Background and aims: The epidemic of diabetes mellitus has made the effective treatment of hyperglycemia a top priority. Maintaining near-normal glycemic levels has been demonstrated to have a beneficial effect on diabetes-specific complications. Insulin can decrease any level of elevated glycated hemoglobin. Insulin glargine (Lantus® is a long-acting insulin analog with a favorable 24-h time-action profile, once daily administration and low risk of hypoglycemia used in type 1 and 2 diabetes. In Romania, real-life data about glycaemic control is lacking. Material and methods: We present results from a retrospective, open-label, non-randomised, registry trial in 2946 Romanian diabetes patients. The objective of the study was to assess the proportion of patients with appropriate glycaemic control after 3 to 6 months of glargine treatment. Results and conclusions: A little over one third of the patients had reached target glycated hemoglobin after 3-6 months of glargine treatment in both types of diabetes. In type 2 diabetes patients the glargine dose used was not high (0.33 UI/kg. Inadequate insulin titration is a possible cause for not reaching glycemic targets.

  13. Cockpit System Situational Awareness Modeling Tool

    Science.gov (United States)

    Keller, John; Lebiere, Christian; Shay, Rick; Latorella, Kara

    2004-01-01

    This project explored the possibility of predicting pilot situational awareness (SA) using human performance modeling techniques for the purpose of evaluating developing cockpit systems. The Improved Performance Research Integration Tool (IMPRINT) was combined with the Adaptive Control of Thought-Rational (ACT-R) cognitive modeling architecture to produce a tool that can model both the discrete tasks of pilots and the cognitive processes associated with SA. The techniques for using this tool to predict SA were demonstrated using the newly developed Aviation Weather Information (AWIN) system. By providing an SA prediction tool to cockpit system designers, cockpit concepts can be assessed early in the design process while providing a cost-effective complement to the traditional pilot-in-the-loop experiments and data collection techniques.

  14. Crowd dynamics evacuations: The roles of shape optimization and real-time computational models. Comment on "Human behaviours in evacuation crowd dynamics: From modelling to "big data" toward crisis management" by Nicola Bellomo et al.

    Science.gov (United States)

    Delle Monache, Maria Laura

    2016-09-01

    This paper focuses on mathematical models for crowd dynamics in real life situations for support to decision making in critical situations. It deals with the modeling and the computations in the light of improving safety and pedestrians behavior.

  15. Modeling Being "Lost": Imperfect Situation Awareness

    Science.gov (United States)

    Middleton, Victor E.

    2011-01-01

    Being "lost" is an exemplar of imperfect Situation Awareness/Situation Understanding (SA/SU) -- information/knowledge that is uncertain, incomplete, and/or just wrong. Being "lost" may be a geo-spatial condition - not knowing/being wrong about where to go or how to get there. More broadly, being "lost" can serve as a metaphor for uncertainty and/or inaccuracy - not knowing/being wrong about how one fits into a larger world view, what one wants to do, or how to do it. This paper discusses using agent based modeling (ABM) to explore imperfect SA/SU, simulating geo-spatially "lost" intelligent agents trying to navigate in a virtual world. Each agent has a unique "mental map" -- its idiosyncratic view of its geo-spatial environment. Its decisions are based on this idiosyncratic view, but behavior outcomes are based on ground truth. Consequently, the rate and degree to which an agent's expectations diverge from ground truth provide measures of that agent's SA/SU.

  16. How Accumulated Real Life Stress Experience and Cognitive Speed Interact on Decision-Making Processes

    Directory of Open Access Journals (Sweden)

    Eva Friedel

    2017-06-01

    Full Text Available Rationale: Advances in neurocomputational modeling suggest that valuation systems for goal-directed (deliberative on one side, and habitual (automatic decision-making on the other side may rely on distinct computational strategies for reinforcement learning, namely model-free vs. model-based learning. As a key theoretical difference, the model-based system strongly demands cognitive functions to plan actions prospectively based on an internal cognitive model of the environment, whereas valuation in the model-free system relies on rather simple learning rules from operant conditioning to retrospectively associate actions with their outcomes and is thus cognitively less demanding. Acute stress reactivity is known to impair model-based but not model-free choice behavior, with higher working memory capacity protecting the model-based system from acute stress. However, it is not clear which impact accumulated real life stress has on model-free and model-based decision systems and how this influence interacts with cognitive abilities.Methods: We used a sequential decision-making task distinguishing relative contributions of both learning strategies to choice behavior, the Social Readjustment Rating Scale questionnaire to assess accumulated real life stress, and the Digit Symbol Substitution Test to test cognitive speed in 95 healthy subjects.Results: Individuals reporting high stress exposure who had low cognitive speed showed reduced model-based but increased model-free behavioral control. In contrast, subjects exposed to accumulated real life stress with high cognitive speed displayed increased model-based performance but reduced model-free control.Conclusion: These findings suggest that accumulated real life stress exposure can enhance reliance on cognitive speed for model-based computations, which may ultimately protect the model-based system from the detrimental influences of accumulated real life stress. The combination of accumulated real life

  17. The Situation Awareness Weighted Network (SAWN) Model

    Science.gov (United States)

    2014-06-01

    under threat or facing a crisis, perceived or actual [Berger & Calabrese 1975, Afifi & Weiner 2002]. Overall, the research indicates that in...Tenney, Y.J., Pew, R.W. (1995) “Situation awareness and the cognitive management of complex systems”, Human Factors 37: 85–104. Afifi , W.A., Weiner

  18. Modeling the situation awareness by the analysis of cognitive process.

    Science.gov (United States)

    Liu, Shuang; Wanyan, Xiaoru; Zhuang, Damin

    2014-01-01

    To predict changes of situation awareness (SA) for pilot operating with different display interfaces and tasks, a qualitative analysis and quantitative calculation joint SA model was proposed. Based on the situational awareness model according to the attention allocation built previously, the pilot cognitive process for the situation elements was analyzed according to the ACT-R (Adaptive Control of Thought, Rational) theory, which explained how the SA was produced. To verify the validity of this model, 28 subjects performed an instrument supervision task under different experiment conditions. Situation Awareness Global Assessment Technique (SAGAT), 10-dimensional Situational Awareness Rating Technique (10-D SART), performance measure and eye movement measure were adopted for evaluating SAs under different conditions. Statistical analysis demonstrated that the changing trend of SA calculated by this model was highly correlated with the experimental results. Therefore the situational awareness model can provide a reference for designing new cockpit display interfaces and help reducing human errors.

  19. Virtual shopping: A viable alternative to direct assessment of real life function?

    Science.gov (United States)

    Greenwood, Kathryn E; Morris, Robin; Smith, Vanessa; Jones, Anna-Marie; Pearman, Douglas; Wykes, Til

    2016-04-01

    Real-life function is markedly impaired in schizophrenia and is an important outcome for interventions, but direct assessment is time consuming and resource intensive. Virtual reality (VR) enables assessment using simulation, akin to real life (RL), but allowing greater experimental control, reliability, and a more timely assessment. This study explores whether VR simulation predicts RL performance in supermarket shopping and how both relate to underlying cognitive abilities. Forty three people with DSM-IV schizophrenia were included in the study. Participants were required to shop for items using a self-directed search in both RL and VR. In each task, accuracy (number of correct items) and efficiency (time taken and number of aisles entered) were measured. IQ, executive function, working memory, spatial memory and social cognition were also assessed. Specific correlations were found between RL accuracy and VR accuracy, and between RL and VR efficiency measures. Multiple regression analyses indicated that VR efficiency measures contributed significant unique variance to RL efficiency outcomes, in addition to that explained by background cognitive measures, with a final model predicting 58% of variance in RL efficiency. VR functional shopping measures may enhance predictions of real life performance, over and above existing cognitive test procedures, and provide a more time-efficient method for evaluating real life outcomes. Copyright © 2016 Elsevier B.V. All rights reserved.

  20. Cognitive Structures, Speech, and Social Situations: Two Integrative Models.

    Science.gov (United States)

    Giles, Howard; Hewstone, Miles

    1982-01-01

    Presents theoretical models of how language acts (1) as a dependent variable of how people subjectively construe situations and (2) as an independent variable creatively defining and redefining situations for those involved. Discusses the importance of developing an interdisciplinary model of language variation in its social context. (EKN)

  1. Using Diagnostic Text Information to Constrain Situation Models

    NARCIS (Netherlands)

    Dutke, S.; Baadte, C.; Hähnel, A.; Hecker, U. von; Rinck, M.

    2010-01-01

    During reading, the model of the situation described by the text is continuously accommodated to new text input. The hypothesis was tested that readers are particularly sensitive to diagnostic text information that can be used to constrain their existing situation model. In 3 experiments, adult part

  2. Supervising PETE Candidates Using the Situational Supervision Model

    Science.gov (United States)

    Levy, Linda S.; Johnson, Lynn V.

    2012-01-01

    Physical education teacher candidates (PETCs) often, as part of their curricular requirements, engage in early field experiences that prepare them for student teaching. Matching the PETC's developmental level with the mentor's supervision style enhances this experience. The situational supervision model, based on the situational leadership model,…

  3. When Cognitive Sciences Meet Real Life

    DEFF Research Database (Denmark)

    Smith, Viktor; Selsøe Sørensen, Henrik; Nissilä, Niina

    2012-01-01

    with his/her existing knowledge, expectations and buying motivations. A cross-disciplinary Danish research project provides a new, shared frame of reference for food manufacturers, authorities, and consumer organisations for assessing in-store food-to-consumer communication from a fairness perspective......Consumers in general pay little attention to food labels. The study of expert-to-layperson communication related to food labels integrates many aspects of what cognitive sciences are about: Knowledge modelling and knowledge transfer, termhood and precision as well as fuzziness, interaction between...

  4. Real-Life Efficacy, Immunogenicity and Safety of Biosimilar Infliximab.

    Science.gov (United States)

    Vegh, Zsuzsanna; Kurti, Zsuzsanna; Lakatos, Peter L

    2017-01-01

    Recently, the use of biosimilar infliximab (IFX) in the treatment of inflammatory bowel diseases has become widespread in some European and non-European countries. Data on the efficacy, safety and immunogenicity from real-life cohorts are accumulating. The first reports showed similar outcomes in the induction and maintenance of remission, mucosal healing, safety and immunogenicity profile to the originator IFX. In the present review, we aimed to summarize the existing knowledge on the efficacy, safety and immunogenicity profile of biosimilar IFX reported from real-life cohorts.

  5. Narrative Construction, Social Perceptions, and the Situation Model.

    Science.gov (United States)

    Costabile, Kristi A

    2016-05-01

    The present investigation examined how three salient features of narrative thinking (situation model construction, linguistic concreteness, and perspective-taking) influenced the social inference process. Results of four experiments indicated that compared with those given other objectives, perceivers given narrative objectives were: (a) more likely to make situation rather than trait attributions for observed behaviors (Experiment 1), (b) less likely to make implicit trait inferences (Experiment 2), and (c) less likely to rely on behavior valence when making evaluative judgments (Experiment 4). Linguistic analyses indicated that narrative construction consistently entailed the creation of situation models of events and linguistic concreteness, but only situation model creation mediated the relationship between narrative and inferences. Experiment 3 confirmed the mediating role of situation models: Perceivers with narrative objectives made trait inferences only when behaviors were inconsistent with contextual information. The role of these core narrative features on social perceptions is discussed.

  6. Modeling Decisional Situations Using Morphological Analysis

    Directory of Open Access Journals (Sweden)

    2007-01-01

    Full Text Available This paper focuses on models of financial decisions in small and medium enterprises. The presented models are a part of a decision support system presented in the PhD dissertation. One of the modeling techniques used for model creation and development is morphological analysis. This technique is used for model scale reduction not by reducing the number of variables involved but by reducing the number of possible combinations between variables. In this paper we prove how this approach can be used in modeling financial decision problems.

  7. Efficient and Flexible KNN Query Processing in Real-Life Road Networks

    DEFF Research Database (Denmark)

    Lu, Yang; Bui, Bin; Zhao, Jiakui;

    2008-01-01

    Along with the developments of mobile services, effectively modeling road networks and efficiently indexing and querying network constrained objects has become a challenging problem. In this paper, we first introduce a road network model which captures real-life road networks better than previous...... models. Then, based on the proposed model, we propose a novel index named the RNG (Road Network Grid) index for accelerating KNN queries and continuous KNN queries over road network constrained data points. In contrast to conventional methods, speed limitations and blocking information of roads...... are included into the RNG index, which enables the index to support both distance-based and time-based KNN queries and continuous KNN queries. Our work extends previous ones by taking into account more practical scenarios, such as complexities in real-life road networks and time-based KNN queries. Extensive...

  8. Three dimensional damage mechanics analysis of real life reactor piping components under various loading conditions

    Energy Technology Data Exchange (ETDEWEB)

    Durgaprasad, P.V.; Sahu, M.K.; Dutta, B.K. (Reactor Safety Division, Bhabha Atomic Research Centre Trombay, Mumbai (India)), e-mail: pvdp@barc.gov.in

    2009-07-01

    In this work, the Gurson-Tvergaard-Needleman (GTN) damage mechanics model is used for the crack growth analysis of real life reactor piping components. The paper also addresses the challenges involved in such analyses. As a part of component integrity testing, a comprehensive experimental program has been pursued to generate the fracture behavior of reactor piping components. Several real life pipes and elbows with various flaw sizes have been tested under different loading conditions like temperature, pressure, bending etc. In the present work, some of the selected components have been analyzed numerically by using parallel in-house finite element code 'MADAM' with GTN constitutive model. The strength of the micro mechanical models has been demonstrated by comparing the numerical results like load v/s. load-line displacements, J-R curves with the experimental data

  9. Constructivist Listening: Real-Life Classroom Management and Discipline Concerns.

    Science.gov (United States)

    McDonald, Nan

    2000-01-01

    Discusses communication obstacles music educators encounter and considers constructivist listening as a means for music educators to assist one another with discipline and management issues. Describes activities for use in a seminar entitled "Real Life in the Music Classroom: Creating Positive Discipline and Management." (CMK)

  10. Clinical and economic impact of etanercept in real-life

    DEFF Research Database (Denmark)

    Larsen, Christian Grønhøj; Andersen, Peter Hundevadt; Lorentzen, Henrik

    2013-01-01

    BACKGROUND: Real-life data on the therapeutic effectiveness and costs of etanercept are scarce. Objectives: To assess the clinical and economic impact of etanercept in patients with psoriasis in Denmark and Norway. MATERIAL & METHODS: This prospective, non-interventional study in a private...

  11. Improvisation of Real-Life Scenarios through Intercultural Competence

    Science.gov (United States)

    Okten, Celile Eren; Griffin, Banu Ozer

    2016-01-01

    This paper describes tasks based on real-life scenarios, which triggered reflective thinking, verbalization, and writing, leading to the creation of natural dialogues rather than artificial, dull monologues. One of the main aims of this approach is to engage students in a dynamic process of both learning about multicultural participants and…

  12. Process Model for Defining Space Sensing and Situational Awareness Requirements

    Science.gov (United States)

    2006-04-01

    process model for defining systems for space sensing and space situational awareness is presented. The paper concentrates on eight steps for determining the requirements to include: decision maker needs, system requirements, exploitation methods and vulnerabilities, critical capabilities, and identify attack scenarios. Utilization of the USAF anti-tamper (AT) implementation process as a process model departure point for the space sensing and situational awareness (SSSA...is presented. The AT implementation process model , as an

  13. A Situative Space Model for Mobile Mixed-Reality Computing

    DEFF Research Database (Denmark)

    Pederson, Thomas; Janlert, Lars-Erik; Surie, Dipak

    2011-01-01

    This article proposes a situative space model that links the physical and virtual realms and sets the stage for complex human-computer interaction defined by what a human agent can see, hear, and touch, at any given point in time.......This article proposes a situative space model that links the physical and virtual realms and sets the stage for complex human-computer interaction defined by what a human agent can see, hear, and touch, at any given point in time....

  14. Comparison of real-life accidental falls in older people with experimental falls in middle-aged test subjects.

    Science.gov (United States)

    Kangas, M; Vikman, I; Nyberg, L; Korpelainen, R; Lindblom, J; Jämsä, T

    2012-03-01

    Falling is a common accident among older people. Automatic fall detectors are one method of improving security. However, in most cases, fall detectors are designed and tested with data from experimental falls in younger people. This study is one of the first to provide fall-related acceleration data obtained from real-life falls. Wireless sensors were used to collect acceleration data during a six-month test period in older people. Data from five events representing forward falls, a sideways fall, a backwards fall, and a fall out of bed were collected and compared with experimental falls performed by middle-aged test subjects. The signals from real-life falls had similar features to those from intentional falls. Real-life forward, sideways and backward falls all showed a pre impact phase and an impact phase that were in keeping with the model that was based on experimental falls. In addition, the fall out of bed had a similar acceleration profile as the experimental falls of the same type. However, there were differences in the parameters that were used for the detection of the fall phases. The beginning of the fall was detected in all of the real-life falls starting from a standing posture, whereas the high pre impact velocity was not. In some real-life falls, multiple impacts suggested protective actions. In conclusion, this study demonstrated similarities between real-life falls of older people and experimental falls of middle-aged subjects. However, some fall characteristics detected from experimental falls were not detectable in acceleration signals from corresponding heterogeneous real-life falls.

  15. Application of the SAROTA index in real-life scenario

    Science.gov (United States)

    Rojatkar, A.; Monebhurrun, V.

    2014-10-01

    A unique parameter referred to as the SAROTA index which accounts for both the specific absorption rate (SAR) and the over-the-air (OTA) performance of a mobile phone was previously proposed to characterize the real-life exposure. The applicability of the SAROTA index was confirmed using SAR and total radiated power (TRP) data obtained under laboratory conditions wherein the power control (PC) enforced on the mobile phone was implemented artificially. Herein the investigation is extended to measurements conducted for the speech mode of operation in real-life scenarios. Based on the actual PC implemented during the communication with the base station, the instantaneous and average real-life exposure experienced by the mobile phone user is analyzed and compared to the predicted SAROTA index. To capture the PC in real-time, a set of hardware modified phones with embedded network monitoring software are used. The instantaneous uplink transmit power level (TX_LEV) along with various downlink parameters such as the receive signal level (RX_LEV) and received signal quality (RX_QUAL) of the communication link are thus available for performing a comprehensive RF exposure analysis.

  16. Trajectories of experience of real life events. A semiotic approach to the dynamics of positioning.

    Science.gov (United States)

    Rosa, Alberto; González, Fernanda

    2013-12-01

    This paper is devoted to the study of experience as a semiotic process of constructing the personal meaning of the situation lived. Its main purpose is to devise a semiotic methodology capable of describing and explaining the dynamics of positioning when facing personal lived experiences in real life contexts. Twenty four young adults were exposed to a simulated conflict and then asked to write a narrative of their understanding of the incident and a self-report of their personal experiences. Results show how narratives and trajectories of experience present different forms in each participant, which could be related to: a) the understanding of the situation lived and the position taken regarding the conflict; and b) the position each participant takes regarding the reports they had to produce for the researchers. The incorporation of reflexivity into the applied method allows identification of how the dynamics of double positioning leave traces in the records produced.

  17. Control of asthma in real life: still a valuable goal?

    Directory of Open Access Journals (Sweden)

    Andriana I. Papaioannou

    2015-06-01

    Full Text Available Although studies show that control of asthma can be achieved in the majority of patients, surveys repeatedly show that this is not the case in real life. Important measures to implement in order to achieve asthma control are trained healthcare professionals, a good patient–doctor relationship, patient education, avoidance of exposure to triggers, personalised management and adherence to treatment. These measures help the majority of asthma patients but have not yet been widely implemented and there should be a concerted action for their implementation. Moreover, further and focused research is needed in severe/refractory asthma.

  18. Online Game Player Personality and Real-life Need Fulfillment

    Directory of Open Access Journals (Sweden)

    Ching-I Teng

    2009-12-01

    Full Text Available This study investigates the relationship between personality and real-life need fulfillment of 114 online game adolescent players, who had an average of 14.86 years in age and a standard deviation of 1.40 years. Of the sample, 73.7% were male and 88.8% had a monthly income below US $90. Results indicate that openness negatively correlated to fulfillment of needs for achievement and affiliation. Conscientiousness positively correlated to fulfillment of needs for achievement, affiliation, autonomy, and dominance. Extraversion positively correlated to fulfillment of needs for affiliation and dominance.

  19. Images of eyes enhance investments in a real-life public good.

    Directory of Open Access Journals (Sweden)

    Damien Francey

    Full Text Available A key issue in cooperation research is to determine the conditions under which individuals invest in a public good. Here, we tested whether cues of being watched increase investments in an anonymous public good situation in real life. We examined whether individuals would invest more by removing experimentally placed garbage (paper and plastic bottles from bus stop benches in Geneva in the presence of images of eyes compared to controls (images of flowers. We provided separate bins for each of both types of garbage to investigate whether individuals would deposit more items into the appropriate bin in the presence of eyes. The treatment had no effect on the likelihood that individuals present at the bus stop would remove garbage. However, those individuals that engaged in garbage clearing, and were thus likely affected by the treatment, invested more time to do so in the presence of eyes. Images of eyes had a direct effect on behaviour, rather than merely enhancing attention towards a symbolic sign requesting removal of garbage. These findings show that simple images of eyes can trigger reputational effects that significantly enhance on non-monetary investments in anonymous public goods under real life conditions. We discuss our results in the light of previous findings and suggest that human social behaviour may often be shaped by relatively simple and potentially unconscious mechanisms instead of very complex cognitive capacities.

  20. A Novel Study: A Situation Model Analysis of Reading Times

    Science.gov (United States)

    McNerney, M. Windy; Goodwin, Kerri A.; Radvansky, Gabriel A.

    2011-01-01

    One of the basic findings on situation models and language comprehension is that reading times are affected by the changing event structure in a text. However, many studies have traditionally used multiple, relatively short texts, in which there is little event consistency across the texts. It is unclear to what extent such changes will be…

  1. Object relations and real life relationships: a cross method assessment.

    Science.gov (United States)

    Handelzalts, Jonathan E; Fisher, Shimrit; Naot, Rachel

    2014-04-01

    This study examines the relationship between the psychoanalytic concept of object relations and real life behavior of being in an intimate relationship among heterosexual women. In a multi-method approach we used two different measures; the self-report Bell Object Relations and Reality Testing Inventory (BORRTI; Bell, Billington & Becker, 1986) and the performance based Thematic Apperception Test (TAT) Social Cognition & Object Relations Scale- Global Rating Method SCORS-G (Westen, 1995) to measure the object relations of 60 women. The Alienation subscale of the BORRTI and understanding of social causality subscale of the SCORS-G explained 34.8% of variance of the intimate relationship variable. Thus, women involved in a romantic relationship reported lower rates of alienation on the BORRTI and produced TAT narratives that were more adaptive with regard to understanding of social causality as measured by the SCORS-G than those not currently in a relationship. Results are discussed with reference to the relationship between object relations and real life measures of healthy individuals and in light of the need for a multi-method approach of assessment.

  2. 一种支持广义服务组合的遗传算法%A Genetic Algorithm for Generalized Real-Life Service Composition

    Institute of Scientific and Technical Information of China (English)

    王显志; 王忠杰; 徐晓飞; 莫同

    2009-01-01

    In the last decade,selection and composition of Web services have drawn increasing attentions.However,real-life services are not only web services but complicated eco-systems composed of various service elements like human,resources,environment,ete,and existing service composition methods cannot be directly applied to such real-life service composition scenarios.In this paper,we propose a conceptual model for generalized real-life service composition.In this model,service behaviors are abstracted as service components and uniformly described by XML.Various service requirements raised by customers are completely listed and classified.Based on these works,a genetic algorithm for real-life service composition is presented to select the best matching service components and compose them together.The algorithm's effectiveness of obtaining optimal solution is proved by a prototype system.

  3. A Situated Model of Creative Learning - Keynote at EERA, Istanbul

    DEFF Research Database (Denmark)

    Tanggaard, Lene

    This presentation puts forward a situated model of creative learning. Most educational studies on creativity tend to concentrate on explaining the relation between teaching and creativity while keeping learning as a secondary concept (Torrance, 1972; Hennessey & Amabile, 1987; De Bono, 1992; Fasko......) Experimentation and inquiry learning and 3) Resistance from the material of interest. As a theoretical point of departure, I will outline a situated model of creativity and learning, and following this, I will introduce my model of creative learning and the basic components of a creative learning community......, 2000-2001). However, Anna Craft (2005) has stated that it is likely that teaching creatively leads to creative learning, suggesting that there is a need to describe the concept of creative learning and to analyze its possible constituents. Accordingly, this presentation introduces an empirically based...

  4. Do children do what they say? Responses to hypothetical and real-life social problems in children with mild intellectual disabilities and behaviour problems

    NARCIS (Netherlands)

    van Nieuwenhuijzen, M; Bijman, ER; Lamberix, ICW; Wijnroks, L; de Castro, BO; Vermeer, A; Matthys, W

    2005-01-01

    Background Most research on children's social problem-solving skills is based on responses to hypothetical vignettes. Just how these responses relate to actual behaviour in real-life social situations is, however, unclear, particularly for children with mild intellectual disabilities (MID). Method I

  5. From bioterrorism exercise to real-life public health crisis: lessons for emergency hotline operations.

    Science.gov (United States)

    Uscher-Pines, Lori; Bookbinder, Sylvia H; Miro, Suzanne; Burke, Thomas

    2007-01-01

    Although public health agencies routinely operate hotlines to communicate key messages to the public, they are rarely evaluated to improve hotline management. Since its creation in 2003, the New Jersey Department of Health & Senior Services' Emergency Communications Center has confronted two large-scale incidents that have tested its capabilities in this area. The influenza vaccine shortage of 2004 and the April 2005 TOPOFF 3 full-scale bioterrorism exercise provided both real-life and simulated crisis situations from which to derive general insights into the strengths and weaknesses of hotline administration. This article identifies problems in the areas of staff and message management by analyzing call volume data and the qualitative observations of group feedback sessions and semistructured interviews with hotline staff. It also makes recommendations based on lessons learned to improve future hotline operations in public health emergencies.

  6. A Simulation and Modeling Framework for Space Situational Awareness

    Science.gov (United States)

    Olivier, S.

    This paper describes the development and initial demonstration of a new, integrated modeling and simulation framework, encompassing the space situational awareness enterprise, for quantitatively assessing the benefit of specific sensor systems, technologies and data analysis techniques. This framework includes detailed models for threat scenarios, signatures, sensors, observables and knowledge extraction algorithms. The framework is based on a flexible, scalable architecture to enable efficient simulation of the current SSA enterprise, and to accommodate future advancements in SSA systems. In particular, the code is designed to take advantage of massively parallel computer systems available, for example, at Lawrence Livermore National Laboratory. We will describe the details of the modeling and simulation framework, including hydrodynamic models of satellite intercept and debris generation, orbital propagation algorithms, radar cross section calculations, optical and infra-red brightness calculations, generic radar system models, generic optical and infra-red system models, specific Space Surveillance Network models, object detection algorithms, orbit determination algorithms, and visualization tools. The specific modeling of the Space Surveillance Network is performed in collaboration with the Air Force Space Command Space Control Group. We will demonstrate the use of this integrated simulation and modeling framework on specific threat scenarios, including space debris and satellite maneuvers, and we will examine the results of case studies involving the addition of new sensor systems, used in conjunction with the Space Surveillance Network, for improving space situational awareness.

  7. Learning to attend: a connectionist model of situated language comprehension.

    Science.gov (United States)

    Mayberry, Marshall R; Crocker, Matthew W; Knoeferle, Pia

    2009-05-01

    Evidence from numerous studies using the visual world paradigm has revealed both that spoken language can rapidly guide attention in a related visual scene and that scene information can immediately influence comprehension processes. These findings motivated the coordinated interplay account (Knoeferle & Crocker, 2006) of situated comprehension, which claims that utterance-mediated attention crucially underlies this closely coordinated interaction of language and scene processing. We present a recurrent sigma-pi neural network that models the rapid use of scene information, exploiting an utterance-mediated attentional mechanism that directly instantiates the CIA. The model is shown to achieve high levels of performance (both with and without scene contexts), while also exhibiting hallmark behaviors of situated comprehension, such as incremental processing, anticipation of appropriate role fillers, as well as the immediate use, and priority, of depicted event information through the coordinated use of utterance-mediated attention to the scene.

  8. A Simulation and Modeling Framework for Space Situational Awareness

    Energy Technology Data Exchange (ETDEWEB)

    Olivier, S S

    2008-09-15

    This paper describes the development and initial demonstration of a new, integrated modeling and simulation framework, encompassing the space situational awareness enterprise, for quantitatively assessing the benefit of specific sensor systems, technologies and data analysis techniques. The framework is based on a flexible, scalable architecture to enable efficient, physics-based simulation of the current SSA enterprise, and to accommodate future advancements in SSA systems. In particular, the code is designed to take advantage of massively parallel computer systems available, for example, at Lawrence Livermore National Laboratory. The details of the modeling and simulation framework are described, including hydrodynamic models of satellite intercept and debris generation, orbital propagation algorithms, radar cross section calculations, optical brightness calculations, generic radar system models, generic optical system models, specific Space Surveillance Network models, object detection algorithms, orbit determination algorithms, and visualization tools. The use of this integrated simulation and modeling framework on a specific scenario involving space debris is demonstrated.

  9. Intriguingly Real Life of the Queen of Crime

    Directory of Open Access Journals (Sweden)

    Branka Kovačević

    2016-12-01

    Full Text Available This December it will be ninety years since Agatha Christie disappeared for eleven days and despite the fact that there are many biographical books about her life and work, nobody knows for sure what provoked her to vanish, sending shockwaves in British society in 1926. Whatever the cause may be, this disappearance has remained a mystery and inspired French authors Anne Martinetti and Guillaume Lebeau, along with the illustrator Alexandre Franc, to create a graphic novel: Agatha: The Real Life of Agatha Christie. Marinetti has also written a cookbook inspired by Agatha Christie, entitled Creams and Punishments, while together with Lebeau, she has co-authored the encyclopedia Agatha Christie from A to Z.Agatha: The Real Life of Agatha Christie was originally released in 2014 as a French-language Kindle edition and was first published in English in May, 2016 by the UK press SelfMadeHero, which specializes in graphic novels and manga adaptations of classic literature, like those of Shakespeare, Poe and Kafka. The story is told through 112 illustrated pages and concludes with a thorough timeline of key events in Agatha Christie’s life, as well as a complete bibliography. It is noticeable that novels and story collections featuring Hercule Poirot take up the greater part of her bibliography. The authors of this biography assume a similar approach in showing the significance of this fictional character in Christie's career (and life, representing Poirot throughout the text as her companion and advisor without using any graphic techniques to stress the fictionality of his character. The authors make strong attempts to convey the close relationship that Christie built with her most prominent character, one who always seems to appear in this biography during her moments of extreme loneliness, and one to whom Christie owed a great deal – as she admited herself when she decided to buy the Greenway House in December 1938 (Martinetti, Lebeau, and Franc

  10. Quantum cryptography in real-life applications: Assumptions and security

    Science.gov (United States)

    Zhao, Yi

    Quantum cryptography, or quantum key distribution (QKD), provides a means of unconditionally secure communication. The security is in principle based on the fundamental laws of physics. Security proofs show that if quantum cryptography is appropriately implemented, even the most powerful eavesdropper cannot decrypt the message from a cipher. The implementations of quantum crypto-systems in real life may not fully comply with the assumptions made in the security proofs. Such discrepancy between the experiment and the theory can be fatal to the security of a QKD system. In this thesis we address a number of these discrepancies. A perfect single-photon source is often assumed in many security proofs. However, a weak coherent source is widely used in a real-life QKD implementation. Decoy state protocols have been proposed as a novel approach to dramatically improve the performance of a weak coherent source based QKD implementation without jeopardizing its security. Here, we present the first experimental demonstrations of decoy state protocols. Our experimental scheme was later adopted by most decoy state QKD implementations. In the security proof of decoy state protocols as well as many other QKD protocols, it is widely assumed that a sender generates a phase-randomized coherent state. This assumption has been enforced in few implementations. We close this gap in two steps: First, we implement and verify the phase randomization experimentally; second, we prove the security of a QKD implementation without the coherent state assumption. In many security proofs of QKD, it is assumed that all the detectors on the receiver's side have identical detection efficiencies. We show experimentally that this assumption may be violated in a commercial QKD implementation due to an eavesdropper's malicious manipulation. Moreover, we show that the eavesdropper can learn part of the final key shared by the legitimate users as a consequence of this violation of the assumptions.

  11. A Situated Model of Creative Learning - Keynote at EERA, Istanbul

    DEFF Research Database (Denmark)

    Tanggaard, Lene

    , 2000-2001). However, Anna Craft (2005) has stated that it is likely that teaching creatively leads to creative learning, suggesting that there is a need to describe the concept of creative learning and to analyze its possible constituents. Accordingly, this presentation introduces an empirically based......) Experimentation and inquiry learning and 3) Resistance from the material of interest. As a theoretical point of departure, I will outline a situated model of creativity and learning, and following this, I will introduce my model of creative learning and the basic components of a creative learning community...

  12. Situation models, mental simulations, and abstract concepts in discourse comprehension.

    Science.gov (United States)

    Zwaan, Rolf A

    2016-08-01

    This article sets out to examine the role of symbolic and sensorimotor representations in discourse comprehension. It starts out with a review of the literature on situation models, showing how mental representations are constrained by linguistic and situational factors. These ideas are then extended to more explicitly include sensorimotor representations. Following Zwaan and Madden (2005), the author argues that sensorimotor and symbolic representations mutually constrain each other in discourse comprehension. These ideas are then developed further to propose two roles for abstract concepts in discourse comprehension. It is argued that they serve as pointers in memory, used (1) cataphorically to integrate upcoming information into a sensorimotor simulation, or (2) anaphorically integrate previously presented information into a sensorimotor simulation. In either case, the sensorimotor representation is a specific instantiation of the abstract concept.

  13. Can virtual reality exposure therapy gains be generalized to real-life? A meta-analysis of studies applying behavioral assessments.

    Science.gov (United States)

    Morina, Nexhmedin; Ijntema, Hiske; Meyerbröker, Katharina; Emmelkamp, Paul M G

    2015-11-01

    In virtual reality exposure therapy (VRET), patients are exposed to virtual environments that resemble feared real-life situations. The aim of the current study was to assess the extent to which VRET gains can be observed in real-life situations. We conducted a meta-analysis of clinical trials applying VRET to specific phobias and measuring treatment outcome by means of behavioral laboratory tests or recordings of behavioral activities in real-life. Data sources were searches of databases (Medline, PsycInfo, and Cochrane). We included in total 14 clinical trials on specific phobias. Results revealed that patients undergoing VRET did significantly better on behavioral assessments following treatment than before treatment, with an aggregated uncontrolled effect size of g = 1.23. Furthermore, patients undergoing VRET performed better on behavioral assessments at post-treatment than patients on wait-list (g = 1.41). Additionally, results of behavioral assessment at post-treatment and at follow-up revealed no significant differences between VRET and exposure in vivo (g = -0.09 and 0.53, respectively). Finally, behavioral measurement effect sizes were similar to those calculated from self-report measures. The findings demonstrate that VRET can produce significant behavior change in real-life situations and support its application in treating specific phobias. Copyright © 2015 Elsevier Ltd. All rights reserved.

  14. Exploring the neural basis of real-life joint action: measuring brain activation during joint table setting with functional near-infrared spectroscopy (fNIRS

    Directory of Open Access Journals (Sweden)

    Johanna eEgetemeir

    2011-09-01

    Full Text Available Many everyday life situations require two or more individuals to execute actions together. Assessing brain activation during naturalistic tasks to uncover relevant processes underlying such real-life joint action situations has remained a methodological challenge. In the present study, we introduce a novel joint action paradigm that enables the assessment of brain activation during real-life joint action tasks using functional near-infrared spectroscopy (fNIRS. We monitored brain activation of participants who coordinated complex actions with a partner sitting opposite them. Participants performed table-setting tasks, either alone (solo action or in cooperation with a partner (joint action, or they observed the partner performing the task (action observation. Comparing joint action and solo action revealed stronger activation (higher [oxy-Hb]-concentration during joint action in a number of areas. Among these were areas in the inferior parietal lobule (IPL that additionally showed an overlap of activation during action observation and solo action. Areas with such a close link between action observation and action execution have been associated with action simulation processes. The magnitude of activation in these IPL areas also varied according to joint action type and its respective demand on action simulation. The results validate fNIRS as an imaging technique for exploring the functional correlates of interindividual action coordination in real-life settings and suggest that coordinating actions in real-life situations requires simulating the actions of the partner.

  15. Critical Care Nurses Inadequately Assess SAPS II Scores of Very Ill Patients in Real Life

    Directory of Open Access Journals (Sweden)

    Andreas Perren

    2012-01-01

    Full Text Available Background. Reliable ICU severity scores have been achieved by various healthcare workers but nothing is known regarding the accuracy in real life of severity scores registered by untrained nurses. Methods. In this retrospective multicentre audit, three reviewers independently reassessed 120 SAPS II scores. Correlation and agreement of the sum-scores/variables among reviewers and between nurses and the reviewers’ gold standard were assessed globally and for tertiles. Bland and Altman (gold standard—nurses of sum scores and regression of the difference were determined. A logistic regression model identifying risk factors for erroneous assessments was calculated. Results. Correlation for sum scores among reviewers was almost perfect (mean ICC = 0.985. The mean (±SD nurse-registered SAPS II sum score was 40.3±20.2 versus 44.2±24.9 of the gold standard (32 points scores. The lowest agreement was found in high SAPS II tertiles for haemodynamics (k = 0.45–0.51. Conclusions. In real life, nurse-registered SAPS II scores of very ill patients are inaccurate. Accuracy of scores was not associated with nurses’ characteristics.

  16. Situated modelling in the drawing workshop for bobbin lace.

    Science.gov (United States)

    Saldanhar, Maria Christine Werba; de Almeida, Juliana Donato

    2012-01-01

    The current article presents the process of situated modeling in the drawing workshop for bobbin lace developed and implemented in the Núcleo de Produção Artesanal Rendeiras da Vila, in Ponta Negra, Natal-Brasil. The workshop aimed to rescue the domain over the product in the production of bobbin lace through capacitation of both experienced and novice craftswomen. The modeling of the drawing workshop was grounded on the sociotechnical construction and in the concepts of anthropotechnology and also social technology. The modelling required an intense process of social construction involving the members of GREPE-UFRN (Group of extension and Research in Ergonomics) and the lacemakers od the community. The domain of drawing the lace has enabled the expression of the craftswomen creativity, increasing the amount of works and the sustainable development,thus reducing the risks of extinction of such art in the Village of Ponta Negra.

  17. The Venus effect in real life and in photographs.

    Science.gov (United States)

    Bertamini, Marco; Lawson, Rebecca; Jones, Luke; Winters, Madeline

    2010-10-01

    The toilet of Venus is the subject of many paintings. Typically, Venus appears with a small mirror in which her face is visible. Observers tend to say that Venus is admiring herself in a mirror, even when the location of the mirror makes this impossible. We demonstrate that the Venus effect is not specific to paintings by showing that it occurs in real life (Experiment 1) and in photographs (Experiments 1-4). The original description of the effect implied that observers describe Venus as seeing in a mirror what they (the observers) see. We used different photographs to compare the responses when the person in front of the mirror could or could not see him or herself and when the image of his or her face was or was not visible to the observer. Observers tend to state that a person can see his or her own reflection when he or she appears near a mirror, whether or not his or her face is visible in the mirror. A task based on a top-down view of a room confirmed that people lack sensitivity to the role of the viewpoint (Experiment 5). We discuss these findings in relation to other evidence of difficulty in understanding what is visible in a mirror.

  18. Solving Real-Life Problems: Future Mobile Technology Sophistication

    Directory of Open Access Journals (Sweden)

    FARHAN SHAFIQ

    2016-07-01

    Full Text Available Almost all the human being real life concerned domains are taking advantage of latest technologies for enhancing their process, procedures and operations. This integration of technological innovations provides ease of access, flexibility, transparency, reliability and speed for the concerned process and procedures. Rapid growth of ICT (Information and Communication Technology and MT (Mobile Technology provides opportunity to redesign and reengineered the human routines? life activities process and procedures. Technology integration and adoption in routine life activities may serves compensatory mechanism to assist the population in different manner such as monitoring older adults and children at homes, provides security assistance, monitoring and recording patients vital signs automatically, controlling and monitoring equipments and devices, providing assistance in shopping, banking and education as well. Disasters happened suddenly, destroy everything indiscriminately. Adoption and integration of latest technologies including ICT and MT can enhance the current disaster management process, procedures and operations. This research study focuses the impacts of latest and emerging technology trends in routine life activities and surrounds their potential strength to improve and enhance disaster management activities. MT is providing a promising platform for facilitating people to enhance their routine life activities. This research argue that integration and adoption of mobile computing in disaster management domain can enhance disaster management activities with promising minimizing error, quick information assembling, quick response based on technology manipulation and prioritizing action.

  19. [Applying mencian's "mind of compassion" to real life situations in nursing practice].

    Science.gov (United States)

    Lee, Mei-Hsiu

    2011-06-01

    "Mind of Compassion", as elaborated by Mencius, emphasizes practice in life. It is a concept also highly valued in Confucian. The moral practice stressed by Confucian is a categorical imperative. Because the main concern is on life itself, moral actions should be taken "as is," without the need to refer to any other conditions. Nursing practice deals with patient diseases and death. Such is precisely the environment in which moral practice should take place. Professional healthcare workers may make very good use of the values and meanings of this moral practice and employ such to its fullest. As Mencius' "Mind of Compassion" reflects the main essence of nursing practice, its elaboration can be highly beneficial in nursing care. This article uses Mencius' concept as well as relevant Western theories and concepts (e.g., caring, empathy and sympathy) to clarify the main values and ways to practice a meaningful life.

  20. Emulating real-life situations with a play task to observe parenting skills and child behaviors.

    Science.gov (United States)

    Rusby, Julie C; Metzler, Carol W; Sanders, Matthew R; Crowley, Ryann

    2015-04-01

    Play tasks that use standardized procedures and materials are a practical way to assess parenting skills, child behaviors, and the ways in which parents and children interact. We describe a systematic process for developing the parent-child play task (PCPT) to assess mother-child interactions for a randomized controlled trial of a video-based parenting program. Participants were 307 mothers and their 3- to 6-year-old children who presented oppositional and disruptive behavior challenges. The validity of the PCPT was investigated by testing (a) the extent to which the tasks elicited the specific parent and child behaviors of interest, (b) the consistency of individuals' behavior across the play tasks, and (c) the concurrent associations of the PCPT-observed child behaviors and mother reports of child behavior. The different tasks elicited the mother and child behaviors that they were designed to elicit. Behavior consistency across tasks for individual mothers and children was fair to good, with the exception of 2 task-specific behaviors. Mother's guidance (provision of instructions to foster a skill) during the teaching task and children's interruptions while mother was busy during the questionnaire task were highly task specific. Modest associations were found between observed children's noncompliance and inappropriate behaviors and mother-reported conduct problems and oppositional behaviors. Implications for clinical and research assessments are discussed. (c) 2015 APA, all rights reserved).

  1. Case studies in food safety and authenticity: Lessons from real-life situations

    DEFF Research Database (Denmark)

    The identification and control of food contaminants rely on careful investigation and implementation of appropriate management strategies. Using a wide range of worldwide examples, this book provides a vital insight into the practical application of strategies for control and prevention. The cont......The identification and control of food contaminants rely on careful investigation and implementation of appropriate management strategies. Using a wide range of worldwide examples, this book provides a vital insight into the practical application of strategies for control and prevention....... The contents are divided into six parts, covering outbreak investigations, source tracing, crisis management, farm-level interventions, safe food production and food adulteration and authenticity. Each chapter is organized as an independent story/case study that has evolved over a certain period of time...... the learning process. Some are supported by illustrations, graphs, photos or maps. The case studies examine among other food products: bakery products, fresh produce, sprouted seeds, drinking water, chicken products, cattle, milk and raw milk, fresh herbs, meat, street foods, dairy foods, animal feed, rice...

  2. BioSensing: using motion sensors in real life care situations

    NARCIS (Netherlands)

    Vlaskamp, F.; Cremers, G.; Pas, R.; Arts, C.; Bonroy, B.; Gransier, R.; Kalisvaart, S.H.; Kerkhofs, V.; Koomen, P.; Lummel, R. van; Meijer, K.; Sauren, H.; Swinkels, M.; Vanrumste, B.; Verschuren, G.; Witte, L. de

    2011-01-01

    Objective. People use pedometers and sport watches to measure calorie use and training performance. Knowing "how you move" is often more important than knowing "how much you move". Measuring "how you move" and feedback to the user is the objective of the BioSensing project. Patients with

  3. Holistic Mathematics Instruction: Interactive Problem Solving and Real Life Situations Help Learners Understand Math Concepts.

    Science.gov (United States)

    Archambeault, Betty

    1993-01-01

    Holistic math focuses on problem solving with numbers and concepts. Whole math activities for adults include shopping for groceries, eating in restaurants, buying gas, taking medicine, measuring a room, estimating servings, and compiling a family cookbook. (SK)

  4. Case studies in food safety and authenticity: Lessons from real-life situations

    DEFF Research Database (Denmark)

    . The contents are divided into six parts, covering outbreak investigations, source tracing, crisis management, farm-level interventions, safe food production and food adulteration and authenticity. Each chapter is organized as an independent story/case study that has evolved over a certain period of time...... the learning process. Some are supported by illustrations, graphs, photos or maps. The case studies examine among other food products: bakery products, fresh produce, sprouted seeds, drinking water, chicken products, cattle, milk and raw milk, fresh herbs, meat, street foods, dairy foods, animal feed, rice...

  5. BioSensing: using motion sensors in real life care situations

    NARCIS (Netherlands)

    Vlaskamp, F.; Cremers, G.; Pas, R.; Arts, C.; Bonroy, B.; Gransier, R.; Kalisvaart, S.H.; Kerkhofs, V.; Koomen, P.; Lummel, R. van; Meijer, K.; Sauren, H.; Swinkels, M.; Vanrumste, B.; Verschuren, G.; Witte, L. de

    2011-01-01

    Objective. People use pedometers and sport watches to measure calorie use and training performance. Knowing "how you move" is often more important than knowing "how much you move". Measuring "how you move" and feedback to the user is the objective of the BioSensing project. Patients with osteoarthri

  6. BioSensing: using motion sensors in real life care situations

    NARCIS (Netherlands)

    Vlaskamp, F.; Cremers, G.; Pas, R.; Arts, C.; Bonroy, B.; Gransier, R.; Kalisvaart, S.H.; Kerkhofs, V.; Koomen, P.; Lummel, R. van; Meijer, K.; Sauren, H.; Swinkels, M.; Vanrumste, B.; Verschuren, G.; Witte, L. de

    2011-01-01

    Objective. People use pedometers and sport watches to measure calorie use and training performance. Knowing "how you move" is often more important than knowing "how much you move". Measuring "how you move" and feedback to the user is the objective of the BioSensing project. Patients with osteoarthri

  7. Some Challenges to the Rough-set Approach to Knowledge Discovery Arising from Real-life Data

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    Since the inception of rough set, significant advances have been made in the theoretical underpinning of the model in general and a large variety of its derivatives in particular. Though some applications have been made with various degrees of success over the years ,the rough set approach to data mining and knowledge discovery in large scale real-life data has not,in the strict sense,been tested. The purpose of rough set is to let data speak for themselves. Thus ,it is intrinsically a theoretical framework catered for real-life data mining and knowledge discovery. However,evidence substantiating such a purpose has been scanty. Often time,theoretical models or arguments are only substantiated by pedagogic examples constructed by the investigators. With the rapid advancement on the theoretical front,it is timely to have a critical scrutiny on the pragmatic side of the research.

  8. Overvoltage Protection of Large Power Transformers - A Real-Life Study Case

    DEFF Research Database (Denmark)

    Bak, Claus Leth; Einarsdottir, K. E.; Andresson, E.

    2008-01-01

    This paper demonstrates the results from a detailed study of the overvoltage protection of a particular 400/150-kV 400-MVA power transformer. The work presented here is based on a real-life power system substation design and data and initiated by Danish TSO Energinet.dk as a consequence of serious...... transformer overvoltage damage. A simulation model for the entire system consisting of overhead line, transformer, surge arrester, and earth grid has been created in PSCAD/EMTDC. The main focus has been put on the earth grid, which has been submodeled in detail in MATLAB using an electromagnetic transient...... approach based on the thin-wire program made by J. H. Richmond for NASA in 1974. The earth grid model is verified with excellent agreement compared to already published results. The overvoltage performance of the particular case is analyzed, and it shows that the transformers LIWL have probably been...

  9. Carbohydrates and exercise performance in non-fasted athletes: A systematic review of studies mimicking real-life

    Directory of Open Access Journals (Sweden)

    Colombani Paolo C

    2013-01-01

    Full Text Available Abstract There is a consensus claiming an ergogenic effect of carbohydrates ingested in the proximity of or during a performance bout. However, in performance studies, the protocols that are used are often highly standardized (e.g. fasted subjects, constant exercise intensity with time-to-exhaustion tests, and do not necessarily reflect competitive real-life situations. Therefore, we aimed at systematically summarizing all studies with a setting mimicking the situation of a real-life competition (e.g., subjects exercising in the postprandial state and with time-trial-like performance tests such as fixed distance or fixed time tests. We performed a PubMed search by using a selection of search terms covering inclusion criteria for sport, athletes, carbohydrates, and fluids, and exclusion criteria for diseases and animals. This search yielded 16,658 articles and the abstract of 16,508 articles contained sufficient information to identify the study as non-eligible for this review. The screening of the full text of the remaining 150 articles yielded 17 articles that were included in this review. These articles described 22 carbohydrate interventions covering test durations from 26 to 241 min (mostly cycling. We observed no performance improvement with half of the carbohydrate interventions, while the other half of the interventions had significant improvement between 1% and 13% (improvement with one of five interventions lasting up to 68 min and with 10 of 17 interventions lasting between 70 and 241 min. Thus, when considering only studies with a setting mimicking real-life competition, there is a mixed general picture about the ergogenic effect of carbohydrates ingested in the proximity of or during a performance bout with an unlikely effect with bouts up to perhaps 70 min and a possible but not compelling ergogenic effect with performance durations longer than about 70 min.

  10. Carbohydrates and exercise performance in non-fasted athletes: a systematic review of studies mimicking real-life.

    Science.gov (United States)

    Colombani, Paolo C; Mannhart, Christof; Mettler, Samuel

    2013-01-28

    There is a consensus claiming an ergogenic effect of carbohydrates ingested in the proximity of or during a performance bout. However, in performance studies, the protocols that are used are often highly standardized (e.g. fasted subjects, constant exercise intensity with time-to-exhaustion tests), and do not necessarily reflect competitive real-life situations. Therefore, we aimed at systematically summarizing all studies with a setting mimicking the situation of a real-life competition (e.g., subjects exercising in the postprandial state and with time-trial-like performance tests such as fixed distance or fixed time tests). We performed a PubMed search by using a selection of search terms covering inclusion criteria for sport, athletes, carbohydrates, and fluids, and exclusion criteria for diseases and animals. This search yielded 16,658 articles and the abstract of 16,508 articles contained sufficient information to identify the study as non-eligible for this review. The screening of the full text of the remaining 150 articles yielded 17 articles that were included in this review. These articles described 22 carbohydrate interventions covering test durations from 26 to 241 min (mostly cycling). We observed no performance improvement with half of the carbohydrate interventions, while the other half of the interventions had significant improvement between 1% and 13% (improvement with one of five interventions lasting up to 68 min and with 10 of 17 interventions lasting between 70 and 241 min). Thus, when considering only studies with a setting mimicking real-life competition, there is a mixed general picture about the ergogenic effect of carbohydrates ingested in the proximity of or during a performance bout with an unlikely effect with bouts up to perhaps 70 min and a possible but not compelling ergogenic effect with performance durations longer than about 70 min.

  11. The influence of illness-related variables, personal resources and context-related factors on real-life functioning of people with schizophrenia

    Science.gov (United States)

    Galderisi, Silvana; Rossi, Alessandro; Rocca, Paola; Bertolino, Alessandro; Mucci, Armida; Bucci, Paola; Rucci, Paola; Gibertoni, Dino; Aguglia, Eugenio; Amore, Mario; Bellomo, Antonello; Biondi, Massimo; Brugnoli, Roberto; Dell'Osso, Liliana; De Ronchi, Diana; Di Emidio, Gabriella; Di Giannantonio, Massimo; Fagiolini, Andrea; Marchesi, Carlo; Monteleone, Palmiero; Oldani, Lucio; Pinna, Federica; Roncone, Rita; Sacchetti, Emilio; Santonastaso, Paolo; Siracusano, Alberto; Vita, Antonio; Zeppegno, Patrizia; Maj, Mario

    2014-01-01

    In people suffering from schizophrenia, major areas of everyday life are impaired, including independent living, productive activities and social relationships. Enhanced understanding of factors that hinder real-life functioning is vital for treatments to translate into more positive outcomes. The goal of the present study was to identify predictors of real-life functioning in people with schizophrenia, and to assess their relative contribution. Based on previous literature and clinical experience, several factors were selected and grouped into three categories: illness-related variables, personal resources and context-related factors. Some of these variables were never investigated before in relationship with real-life functioning. In 921 patients with schizophrenia living in the community, we found that variables relevant to the disease, personal resources and social context explain 53.8% of real-life functioning variance in a structural equation model. Neurocognition exhibited the strongest, though indirect, association with real-life functioning. Positive symptoms and disorganization, as well as avolition, proved to have significant direct and indirect effects, while depression had no significant association and poor emotional expression was only indirectly and weakly related to real-life functioning. Availability of a disability pension and access to social and family incentives also showed a significant direct association with functioning. Social cognition, functional capacity, resilience, internalized stigma and engagement with mental health services served as mediators. The observed complex associations among investigated predictors, mediators and real-life functioning strongly suggest that integrated and personalized programs should be provided as standard treatment to people with schizophrenia. PMID:25273301

  12. Violence Exposure in Real-Life, Video Games, Television, Movies, and the Internet: Is There Desensitization?

    Science.gov (United States)

    Funk, Jeanne B.; Baldacci, Heidi Bechtoldt; Pasold; Tracie; Baumgardner, Jennifer

    2004-01-01

    It is believed that repeated exposure to real-life and to entertainment violence may alter cognitive, affective, and behavioral processes, possibly leading to desensitization. The goal of the present study was to determine if there are relationships between real-life and media violence exposure and desensitization as reflected in related…

  13. Exploring English Language Learners (ELL) Experiences with Scientific Language and Inquiry within a Real Life Context

    OpenAIRE

    Algee, Lisa M.

    2012-01-01

    Abstract Exploring English Language Learners (ELL) Experiences with Scientific Language and Inquiry within a Real Life Context Lisa M. Algee English Language Learners (ELL) are often at a distinct disadvantage from receiving authentic science learning opportunites. This study explored English Language Learners (ELL) learning experiences with scientific language and inquiry within a real life context. This research was theoretically informed by socioc...

  14. Real life testing of a Hybrid PEM Fuel Cell Bus

    Science.gov (United States)

    Folkesson, Anders; Andersson, Christian; Alvfors, Per; Alaküla, Mats; Overgaard, Lars

    Fuel cells produce low quantities of local emissions, if any, and are therefore one of the most promising alternatives to internal combustion engines as the main power source in future vehicles. It is likely that urban buses will be among the first commercial applications for fuel cells in vehicles. This is due to the fact that urban buses are highly visible for the public, they contribute significantly to air pollution in urban areas, they have small limitations in weight and volume and fuelling is handled via a centralised infrastructure. Results and experiences from real life measurements of energy flows in a Scania Hybrid PEM Fuel Cell Concept Bus are presented in this paper. The tests consist of measurements during several standard duty cycles. The efficiency of the fuel cell system and of the complete vehicle are presented and discussed. The net efficiency of the fuel cell system was approximately 40% and the fuel consumption of the concept bus is between 42 and 48% lower compared to a standard Scania bus. Energy recovery by regenerative braking saves up 28% energy. Bus subsystems such as the pneumatic system for door opening, suspension and brakes, the hydraulic power steering, the 24 V grid, the water pump and the cooling fans consume approximately 7% of the energy in the fuel input or 17% of the net power output from the fuel cell system. The bus was built by a number of companies in a project partly financed by the European Commission's Joule programme. The comprehensive testing is partly financed by the Swedish programme "Den Gröna Bilen" (The Green Car). A 50 kW el fuel cell system is the power source and a high voltage battery pack works as an energy buffer and power booster. The fuel, compressed hydrogen, is stored in two high-pressure stainless steel vessels mounted on the roof of the bus. The bus has a series hybrid electric driveline with wheel hub motors with a maximum power of 100 kW. Hybrid Fuel Cell Buses have a big potential, but there are

  15. The Latent Class Model as a Measurement Model for Situational Judgment Tests

    Directory of Open Access Journals (Sweden)

    Frank Rijmen

    2011-11-01

    Full Text Available In a situational judgment test, it is often debatable what constitutes a correct answer to a situation. There is currently a multitude of scoring procedures. Establishing a measurement model can guide the selection of a scoring rule. It is argued that the latent class model is a good candidate for a measurement model. Two latent class models are applied to the Managing Emotions subtest of the Mayer, Salovey, Caruso Emotional Intelligence Test: a plain-vanilla latent class model, and a second-order latent class model that takes into account the clustering of several possible reactions within each hypothetical scenario of the situational judgment test. The results for both models indicated that there were three subgroups characterised by the degree to which differentiation occurred between possible reactions in terms of perceived effectiveness. Furthermore, the results for the second-order model indicated a moderate cluster effect.

  16. APPLICATION OF GIS AND MATHEMATICAL MODELING IN MARITIME CRISIS SITUATIONS

    Directory of Open Access Journals (Sweden)

    Nenad Mladineo

    2010-12-01

    Full Text Available This paper aims to propose a decision support system for maritime crisis situation, due to fact that Croatia has decided to implement Directive 2002/59/EC to define places of refuge for ships in need of assistance off their coasts, or to develop techniques for providing assistance to such ships. In order to fulfill this Directive it is necessary to build an effective Decision Support System (DSS based on GIS and mathematical modeling. The basic module of the proposed system is GIS, for all levels of DSS, that comprise information subsystems about spatial and other data and serves the other modules with data and information. Starting points for analysis are shipping corridors, and 380 potential locations for places of refuge designated in the official navigational pilot book. Multicriteria analysis, with GIS-generated input data, has been used to establish "worthiness" of a place of refuge for each ship category, taking into account kinds of accident. Proposed mathematical models facilitate optimal usage of "available intervention resources".

  17. Rehabilitation of Executive Functions in a Real-Life Setting: Goal Management Training Applied to a Person with Schizophrenia

    Directory of Open Access Journals (Sweden)

    M.-N. Levaux

    2012-01-01

    Full Text Available The aim was to assess the efficacy of a modified version of Goal Management Training (GMT in a person with schizophrenia who had difficulties in attaining the final goal for new and multitasking daily-life situations. GMT is designed to improve abilities in establishing goal-directed plans and carrying them out effectively. Beneficial effects of GMT were measured for several clinical questionnaires, laboratory tasks, and three real-life situations: meal preparation (trained, familiar; washing (nontrained, familiar; meeting preparation (nontrained, unfamiliar. The results revealed improvement in planning and on trained laboratory and meal preparation tasks and a generalization of GMT effects on nontrained laboratory and everyday tasks. Self-esteem also improved. Finally, a two-year followup indicated the durability of the beneficial effects.

  18. "Real-Life" Pulse Flattening on the LLNL Flash X-ray (FXR) Machine

    Energy Technology Data Exchange (ETDEWEB)

    DeHope, W J; Jacob, J S; Kihara, R; Ong, M; Zentler, J M

    2007-06-25

    High-resolution radiography using high-current electron accelerators based on the linear induction accelerator principle requires the linac's final spot on the X-ray target to be millimeter-sized. The requisite final focusing solenoid is adjusted for a specific beam energy at its entrance, hence, temporal variation of entrance beam energy results in a less than optimal time-averaged spot size. The FXR (Flash X-Ray) induction linac facility at Lawrence Livermore National Laboratory will be briefly described with an emphasis on its pulsed power system. In principle, the pulsed Blumleins at the heart of the system output a square pulse when discharged at the peak of their charging waveform so that, with correct cell timing synchronization, the effective beam output into the final focusing solenoid should be optimally flat. We have found that real-life consideration of transmission line and pulse power details in both the injector and accelerator sections of the machine results in significant energy variations in the final beam. We have implemented methods of measurement and analysis that permits this situation to be quantified and improved upon. The improvement will be linked to final beam spot size and enhancement in expected radiographic resolution.

  19. Genetic influence on blood pressure measured in the office, under laboratory stress and during real life

    National Research Council Canada - National Science Library

    Wang, Xiaoling; Ding, Xiuhua; Su, Shaoyong; Harshfield, Gregory; Treiber, Frank; Snieder, Harold

    To determine to what extent the genetic influences on blood pressure (BP) measured in the office, under psychologically stressful conditions in the laboratory and during real life are different from each other...

  20. Cervical and facial infections - a real life threat

    Science.gov (United States)

    Rosu, S.; Fratila, M.

    2014-03-01

    Cervicofacial infections of dental origin are a difficult and complex issue of oral and maxillofacial surgery. Recognizing in due time the situations which are likely to develop a life-threatening condition and medical surgical prompt interventions significantly reduce the rate of the complications. Between January 2009 and March 2013, at the Clinic of Oral and Maxillofacial Surgery of the University of Medicine and Pharmacy "Victor Babes" Timisoara, 17 patients with severe cervicofacial infections were admitted in the emergency department as they needed a complex medical surgical treatment in accordance with protocol established together with the intensive-care department. Assessing the situations, we noticed a difficult, prolonged time of the recovery process which needed a hospitalization period of around 20 days. It recorded two deceased because of cervical necrotizing fasciitis and oral floor phlegmon, the most severe forms of the cervicofacial infections. The severity of the condition of the patients with cervicofacial infections must be figured and as quickly as possible an energetic therapeutic attitude must be adopted. The experience shows a frequent resistance to antibiotics like ampicillin, penicillin and oxacillin. The patients must be guided in due time to a clinic which has an intensive care department, where the surgical treatment must be administrated together with an intensive treatment for supporting the general condition. The reduction of the vital risk of the cervicofacial infections of dental origin will be done through an attentive assessment of the general and local condition (status) of the outpatients, before the dental extraction. The absence of a treatment adapted to the situation and to the clinic development, meaningfully increases the rate of the complications and the length of the hospitalization, the lethal evolution being not excluded.

  1. The Collaborative Apprenticeship Model: Situated Professional Development within School Settings

    Science.gov (United States)

    Glazer, Evan M.; Hannafin, Michael J.

    2006-01-01

    Professional learning is a social enterprise where peers rely on the expertise and support of one another to adopt innovative practices. Reciprocal interactions in a community of practice, where teachers take responsibility for each other's learning and development, may provide an effective means of supporting situated professional learning. We…

  2. Managing Staff Development for Online Education: A Situated Learning Model.

    Science.gov (United States)

    Taylor, Janet A.

    2003-01-01

    Describes the implementation and management of staff development for online education underpinned by the principles of situated learning. Describes technological, human resource, pedagogical, and management initiatives and presents a case study of how a small regional institution changed to being an internationally recognized e-university. (EV)

  3. Multilevel hierarchical kernel spectral clustering for real-life large scale complex networks.

    Directory of Open Access Journals (Sweden)

    Raghvendra Mall

    Full Text Available Kernel spectral clustering corresponds to a weighted kernel principal component analysis problem in a constrained optimization framework. The primal formulation leads to an eigen-decomposition of a centered Laplacian matrix at the dual level. The dual formulation allows to build a model on a representative subgraph of the large scale network in the training phase and the model parameters are estimated in the validation stage. The KSC model has a powerful out-of-sample extension property which allows cluster affiliation for the unseen nodes of the big data network. In this paper we exploit the structure of the projections in the eigenspace during the validation stage to automatically determine a set of increasing distance thresholds. We use these distance thresholds in the test phase to obtain multiple levels of hierarchy for the large scale network. The hierarchical structure in the network is determined in a bottom-up fashion. We empirically showcase that real-world networks have multilevel hierarchical organization which cannot be detected efficiently by several state-of-the-art large scale hierarchical community detection techniques like the Louvain, OSLOM and Infomap methods. We show that a major advantage of our proposed approach is the ability to locate good quality clusters at both the finer and coarser levels of hierarchy using internal cluster quality metrics on 7 real-life networks.

  4. Epistemology, Situated Cognition, and Mental Models: "Like a Bridge over Troubled Water."

    Science.gov (United States)

    Seel, Norbert M.

    2001-01-01

    Discusses situated cognition as a movement from epistemology, considers the construction of mental models, and describes a study of twelfth graders that investigated the significance of a conceptual model provided at the beginning of the learning process. Results show that mental models are constructed in dependence on the learning situation.…

  5. Sustained-release pregabalin with methylcobalamin in neuropathic pain: an Indian real-life experience

    Directory of Open Access Journals (Sweden)

    Dongre YU

    2013-05-01

    Full Text Available Yasmin U Dongre, Onkar C Swami Unichem Laboratories Ltd, Unichem Bhavan, Mumbai, India Introduction: Neuropathic pain is intense in nature and difficult to manage. Thus, the primary goal is maximum relief from pain. The aim of this study was to assess the efficacy and safety of a fixed-dose combination of sustained-release pregabalin and methylcobalamin in reducing neuropathic pain in Indian patients, in the real-life situation. Methods: This was a multicenter, prospective, open-labeled, single-arm, observational, 14-day study. Patients received fixed dose combination of 75 or 150 mg sustained-release pregabalin combined with 1500 mcg immediate release methylcobalamin, depending on the clinical requirement. Data was collected for pain reduction and other positive and negative symptoms associated with neuropathy, including hyperesthesia, paresthesia, numbness/tingling, burning sensation, muscle weakness, sleep disturbances, and impairment of movement. Pain intensity was measured on a ten-point visual analog scale (VAS (0 represented "no pain," and 10 represented "worst pain ever". The safety of the drug was also evaluated throughout the study duration. Data was analyzed using appropriate statistical methods. Results: The overall reduction in mean VAS score over 14 days was 72.3%. The reduction in mean VAS score was significant as early as the first week. Both positive and negative symptoms of peripheral neuropathy were significantly improved in >50% patients within the 2 weeks. Giddiness (4.7%, followed by sedation (3.6%, dizziness (2.9%, drowsiness (2.3%, and nausea (2.3% were the most commonly observed adverse effects. The overall efficacy and tolerability was rated as good to excellent by >95% of the investigators and patients. Conclusion: Fixed dose combination of sustained-release pregabalin and methylcobalamin significantly reduced neuropathic pain, with significant improvement in both the positive and negative symptoms associated with

  6. Embracing the role of real life studies in the management of rare cancers

    Directory of Open Access Journals (Sweden)

    Omar Abdel-Rahman

    2016-10-01

    Full Text Available For commonly occurring cancers, as well as situations or conditions that are frequently encountered in oncological setting, plenty of prospective data are available to oncologists or medical practitioners to facilitate the decision making process. However, for rare cancers and atypical scenarios, there are limited references in the current literature. Understandably, this is attributed to the difficulty in recruiting enough patients to systematically study such rare manifestations. Under these circumstances, the importance of real life data that are collected via population-based studies, case series, and case reports is especially significant. In the current issue of AMOR, the journal features three case reports that describe distinctly uncommon oncological scenarios. In one report, Vafaii and Shao highlighted the stepwise development of classical Hodgkin lymphoma (cHL from diffuse large B cell lymphoma (DLBCL via precursor Reed-Sternberg/Hodgkin cells, as confirmed via multiple biopsies. They suggested that cHL and DLBCL can be clonally related, even when developing metachronously in the same patient, based on the presence of a hybrid intermediate stage. Meanwhile, Xian and colleagues reported the surgical management of brachial plexus pain that is caused by Pancoast tumor. According to them, the condition closely resembles the symptoms of brachial plexus injury and thus, the underlying cause is easily misdiagnosed. Finally, Coehlo and co-workers presented a report on the prolonged disease control of esthesioneuroblastoma using a multimodality approach, combining surgery, radiotherapy, and chemotherapy to derive an effective treatment strategy. It is noteworthy that despite an initial distant metastasis setback, the patient responded positively to palliative chemotherapy, thus proving the value of the much debated approach.In short, these case reports are an invaluable addition to existing medical literature concerning the diagnoses and

  7. Studies in Mathematical Models of Human Decisionmaking in Gaming Situations

    Science.gov (United States)

    1986-04-06

    Risk- Taking Situations," Econometri’:a, 19, pp. 404-437. Arrow, K. 11951b], Social Choice and Individual Values, New Haven: Yale University Press...Under Uncertainty," Progress in Social Psychol,,gy, H. Fishbein (ed.), Hillsdale, New Jersey: Erlbaum. Tversky, A. and D. Kahneman [1981], "The...ASYMPTOTIC AGREEMENT IN DISTRIBUTED ESTIMATION WITH INCONSISTENT BELIEFS* A t. *This research was also ’ supported by DOE contract DEACO-1-80-RA50418 d B-0

  8. When real life wind speed exceeds design wind assumptions

    Energy Technology Data Exchange (ETDEWEB)

    Winther-Jensen, M.; Joergensen, E.R. [Risoe National Lab., Roskilde (Denmark)

    1999-03-01

    Most modern wind turbines are designed according to a standard or a set of standards to withstand the design loads with a defined survival probability. Mainly the loads are given by the wind conditions on the site defining the `design wind speeds`, normally including extreme wind speeds given as an average and a peak value. The extreme wind speeds are normally (e.g. in the upcoming IEC standard for wind turbine safety) defined as having a 50-year recurrence period. But what happens when the 100 or 10,000 year wind situation hits a wind turbine? Results on wind turbines of wind speeds higher than the extreme design wind speeds are presented based on experiences especially from the State of Gujarat in India. A description of the normal approach of designing wind turbines in accordance with the standards in briefly given in this paper with special focus on limitations and built-in safety levels. Based on that, other possibilities than just accepting damages on wind turbines exposed for higher than design wind speeds are mentioned and discussed. The presentation does not intend to give the final answer to this problem but is meant as an input to further investigations and discussions. (au)

  9. Real-life decision making in college students. II: Do individual differences show reliable effects?

    Science.gov (United States)

    Galotti, Kathleen M; Tandler, Jane M; Wiener, Hillary J D

    2014-01-01

    First-year undergraduates participated in a short-term longitudinal study of real-life decision making over their first 14 months of college. They were surveyed about 7 different decisions: choosing courses for upcoming terms (on 3 different occasions), choosing an academic major (twice), planning for the upcoming summer, and planning for sophomore-year housing. They also completed a survey of self-reported decision-making styles and the Need for Cognition survey (Cacioppo & Petty, 1982) to assess their focus on rationality and enjoyment of analytic thinking. Results showed few statistically significant correlations between stylistic measures and behavioral measures of decision making, in either the amount of information considered or the way in which the information integration tracked predictions of linear models of decision making applied to each participant's data. However, there were consistent correlations, across the 7 decisions, between stylistic measures and affective reactions to, or retrospective descriptions of, episodes of decision making. We suggest that decision-making styles instruments may better reflect the construction of narratives of self as a decision maker more than they do actual behavior during decision making.

  10. Implications of the situated learning model for teaching and learning nursing research.

    Science.gov (United States)

    Gieselman, J A; Stark, N; Farruggia, M J

    2000-01-01

    Situated learning theory is gaining increased attention in the fields of human cognition and learning. The authors discuss the key researchers and basic assumptions of situated learning, and outline implications for the design and development of instruction. The authors describe how they applied the situated model to teaching and learning nursing research, an area identified as problematic for staff, administrators, and educators. They describe their personal observations and discuss feedback from participants at the workshop. The authors conclude that the situated model is useful for exposing nurses with little prior research experience to this domain of knowledge.

  11. High correlation between performance on a virtual-reality simulator and real-life cataract surgery

    DEFF Research Database (Denmark)

    Thomsen, Ann Sofia Skou; Smith, Phillip; Subhi, Yousif

    2017-01-01

    -tracking software of cataract surgical videos with a Pearson correlation coefficient of -0.70 (p = 0.017). CONCLUSION: Performance on the EyeSi simulator is significantly and highly correlated to real-life surgical performance. However, it is recommended that performance assessments are made using multiple data......PURPOSE: To investigate the correlation in performance of cataract surgery between a virtual-reality simulator and real-life surgery using two objective assessment tools with evidence of validity. METHODS: Cataract surgeons with varying levels of experience were included in the study. All...... antitremor training, forceps training, bimanual training, capsulorhexis and phaco divide and conquer. RESULTS: Eleven surgeons were enrolled. After a designated warm-up period, the proficiency-based test on the EyeSi simulator was strongly correlated to real-life performance measured by motion...

  12. Modeling of Future Initial Teacher of Foreign Language Training, Using Situation Analysis

    Directory of Open Access Journals (Sweden)

    Maryana М. Sidun

    2012-12-01

    Full Text Available The article discloses the content of modeling of future initial teacher of foreign language, using situation analysis, defines the stages of modeling during the professional competence formation of future teacher of foreign language: preparatory, analytical and executive.

  13. Emotional and physiological desensitization to real-life and movie violence.

    Science.gov (United States)

    Mrug, Sylvie; Madan, Anjana; Cook, Edwin W; Wright, Rex A

    2015-05-01

    Youth are exposed to large amounts of violence in real life and media, which may lead to desensitization. Given evidence of curvilinear associations between exposure to violence and emotional distress, we examined linear and curvilinear associations of exposure to real-life and movie violence with PTSD symptoms, empathy, and physiological arousal, as well emotional and physiological reactivity to movie violence. College students (N = 209; mean age = 18.74) reported on their exposure to real-life and televised violence, PTSD symptoms, and empathy. Then, students were randomly assigned to view a series of violent or nonviolent high-action movie scenes, providing ratings of emotional distress after each clip. Blood pressure was measured at rest and during video viewing. Results showed that with increasing exposure to real-life violence, youth reported more PTSD symptoms and greater identification with fictional characters. Cognitive and emotional empathy increased from low to medium levels of exposure to violence, but declined at higher levels. For males, exposure to higher levels of real-life violence was associated with diminishing (vs. increasing) emotional distress when viewing violent videos. Exposure to televised violence was generally unrelated to emotional functioning. However, those with medium levels of exposure to TV/movie violence experienced lower elevations of blood pressure when viewing violent videos compared to those with low exposure, and those with higher levels of exposure evidenced rapid increase in blood pressure that quickly declined over time. The results point to diminished empathy and reduced emotional reactivity to violence as key aspects of desensitization to real-life violence, and more limited evidence of physiological desensitization to movie violence among those exposed to high levels of televised violence.

  14. Emotional and Physiological Desensitization to Real-Life and Movie Violence

    Science.gov (United States)

    Mrug, Sylvie; Madan, Anjana; Cook, Edwin W.; Wright, Rex A.

    2014-01-01

    Youth are exposed to large amounts of violence in real life and media, which may lead to desensitization. Given evidence of curvilinear associations between exposure to violence and emotional distress, we examined linear and curvilinear associations of exposure to real-life and movie violence with PTSD symptoms, empathy, and physiological arousal, as well emotional and physiological reactivity to movie violence. College students (N=209; mean age=18.74) reported on their exposure to real-life and televised violence, PTSD symptoms, and empathy. Then, students were randomly assigned to view a series of violent or nonviolent high-action movie scenes, providing ratings of emotional distress after each clip. Blood pressure was measured at rest and during video viewing. Results showed that with increasing exposure to real-life violence, youth reported more PTSD symptoms and greater identification with fictional characters. Cognitive and emotional empathy increased from low to medium levels of exposure to violence, but declined at higher levels. For males, exposure to higher levels of real-life violence was associated with diminishing (vs. increasing) emotional distress when viewing violent videos. Exposure to televised violence was generally unrelated to emotional functioning. However, those with medium levels of exposure to TV/movie violence experienced lower elevations of blood pressure when viewing violent videos compared to those with low exposure, and those with higher levels of exposure evidenced rapid increase in blood pressure that quickly declined over time. The results point to diminished empathy and reduced emotional reactivity to violence as key aspects of desensitization to real-life violence, and more limited evidence of physiological desensitization to movie violence among those exposed to high levels of televised violence. PMID:25326900

  15. Social norms and cooperation in real-life social dilemmas

    DEFF Research Database (Denmark)

    Thøgersen, John

    2008-01-01

    types of normative beliefs make it difficult to test the interaction hypothesis. By using structural equation modelling with residual centering these problems are overcome and the interaction hypothesis is confirmed. The result is stable across three replications spanning a two-year period.......The hypothesis that injunctive and descriptive norms interact positively or synergistically to promote cooperation in social dilemmas is tested in the context of a survey study focusing on environmentally responsible behaviour. Measurement error and strong and positive correlations between the two...

  16. Recurrent Neural Networks for Polyphonic Sound Event Detection in Real Life Recordings

    OpenAIRE

    Parascandolo, Giambattista; Huttunen, Heikki; Virtanen, Tuomas

    2016-01-01

    In this paper we present an approach to polyphonic sound event detection in real life recordings based on bi-directional long short term memory (BLSTM) recurrent neural networks (RNNs). A single multilabel BLSTM RNN is trained to map acoustic features of a mixture signal consisting of sounds from multiple classes, to binary activity indicators of each event class. Our method is tested on a large database of real-life recordings, with 61 classes (e.g. music, car, speech) from 10 different ever...

  17. The Analysis of a Real Life Declarative Process

    DEFF Research Database (Denmark)

    Debois, Søren; Slaats, Tijs

    2015-01-01

    This paper reports on a qualitative study of the use of declarative process notations used in a commercial setting. Specifically, we investigate the actual use of a system implemented in terms of DCR graphs for the Danish "Dreyer Foundation" by our industry partner Exformatics A/S. The study...... is performed by analysing logs of actual use of the system. By the study we seek to illuminate the currently open -- and heavily debated! -- research question of whether the claimed advantages in conciseness and flexibility of declarative models over more traditional flow-based notations are significant...... in practice. Studies investigating this question have typically focused on understandability for users, driven by lab experiments and workshops with practitioners unfamiliar with the paradigm. In the present study, we (1) attempt to assess qualitatively whether users employed the flexibility granted them...

  18. Maritime piracy situation modelling with dynamic Bayesian networks

    CSIR Research Space (South Africa)

    Dabrowski, James M

    2015-05-01

    Full Text Available A generative model for modelling maritime vessel behaviour is proposed. The model is a novel variant of the dynamic Bayesian network (DBN). The proposed DBN is in the form of a switching linear dynamic system (SLDS) that has been extended into a...

  19. Survey of current situation in radiation belt modeling

    Science.gov (United States)

    Fung, Shing F.

    2004-01-01

    The study of Earth's radiation belts is one of the oldest subjects in space physics. Despite the tremendous progress made in the last four decades, we still lack a complete understanding of the radiation belts in terms of their configurations, dynamics, and detailed physical accounts of their sources and sinks. The static nature of early empirical trapped radiation models, for examples, the NASA AP-8 and AE-8 models, renders those models inappropriate for predicting short-term radiation belt behaviors associated with geomagnetic storms and substorms. Due to incomplete data coverage, these models are also inaccurate at low altitudes (e.g., radiation data from modern space missions and advancement in physical modeling and data management techniques have now allowed the development of new empirical and physical radiation belt models. In this paper, we will review the status of modern radiation belt modeling. Published by Elsevier Ltd on behalf of COSPAR.

  20. Personal attitudes toward time: The relationship between temporal focus, space-time mappings and real life experiences.

    Science.gov (United States)

    Li, Heng; Cao, Yu

    2017-06-01

    What influences how people implicitly associate "past" and "future" with "front" and "back?" Whereas previous research has shown that cultural attitudes toward time play a role in modulating space-time mappings in people's mental models (de la Fuente, Santiago, Román, Dumitrache & Casasanto, 2014), we investigated real life experiences as potential additional influences on these implicit associations. Participants within the same single culture, who are engaged in different intermediate-term educational experiences (Study 1), long-term living experiences (Study 2), and short-term visiting experiences (Study 3), showed their distinct differences in temporal focus, thereby influencing their implicit spatializations of time. Results across samples suggest that personal attitudes toward time related to real life experiences may influence people's space-time mappings. The findings we report on shed further light on the high flexibility of human conceptualization system. While culture may exert an important influence on temporal focus, a person's conceptualization of time may be attributed to a culmination of factors. © 2017 Scandinavian Psychological Associations and John Wiley & Sons Ltd.

  1. Real-Life Treatment Paradigms Show Adalimumab Is Cost-Effective for the Management of Ulcerative Colitis

    Directory of Open Access Journals (Sweden)

    Candace L. Beilman

    2016-01-01

    Full Text Available Background. Adalimumab is effective for the maintenance of remission in patients with moderate-to-severe ulcerative colitis (UC. Currently, biologic therapies are used in cases where patients fail conventional medical therapies. If biologic therapies are not available, patients often choose to remain in an unwell state rather than undergo colectomy. Objective. The aim of the study was to evaluate the cost-effectiveness of adalimumab in patients with UC where adalimumab was readily available compared to not available. Methods. A previously validated Markov model was used to simulate disease progression of patients with UC who are corticosteroid-dependent and/or did not respond to thiopurine therapy. Utility scores and transition probabilities between health states were determined by using data from randomized controlled trials and real-life observational studies. Costs were obtained from the Ontario Case Costing Initiative and the Alberta Health Schedule of Medical Benefits. Results. The incremental cost-effectiveness ratios for readily available adalimumab treatment of UC were $40,000 and $59,000 per quality-adjusted life year, compared with ongoing medical therapy in an unwell state, at 5-year and 10-year treatment time horizons, respectively. Conclusion. Considering real-life patient preferences to avoid colectomy, adalimumab is cost-effective according to a willingness-to-pay threshold of $80,000 for treatment of UC.

  2. Gross情绪调节过程模型及其应用——以认知改变为例%A Real-life Reflection of Gross's Emotion Regulation Process Model Related to the effect of Comprehension on Cognitive Change

    Institute of Scientific and Technical Information of China (English)

    黄红嫂

    2012-01-01

    The ability of emotion regulation is an important reflection of the five key points in Gross emotion regulation and the process model, situation attention deployment, cognitive change and response modulation. Combination of emotional intelligence. There are selection, situation modification, daily life, we can sort out many of adjustment ways on every key point to better rule out the emotional distress.%情绪调节能力是个体情绪智能水平高低的重要反映。Gross的情绪调节过程模型中有情境选择、情境修正、注意分配、认知改变和反应调整五个关键点。结合现实生活,我们可以在每个控制点整理出很多实用的调节方法,以更好地排除日常情绪困扰。

  3. Transition from Model to Proof: Example of Water Treatment Plant

    Science.gov (United States)

    Güler, Gürsel

    2016-01-01

    The aim of this study was to research the prospective mathematics teachers' ability to construct a mathematical model for a real life problem and to prove these models by generalizing them to use in similar situations. The study was conducted with 129 prospective teachers determined on a volunteering basis. The data were obtained with the help of…

  4. Modelling of human transplacental transport as performed in Copenhagen, Denmark

    DEFF Research Database (Denmark)

    Mathiesen, Line; Mørck, Thit Aarøe; Zuri, Giuseppina

    2014-01-01

    Placenta perfusion models are very effective when studying the placental mechanisms in order to extrapolate to real-life situations. The models are most often used to investigate the transport of substances between mother and foetus, including the potential metabolism of these. We have studied th...

  5. Tests of control in the Audit Risk Model : Effective? Efficient?

    NARCIS (Netherlands)

    Blokdijk, J.H. (Hans)

    2004-01-01

    Lately, the Audit Risk Model has been subject to criticism. To gauge its validity, this paper confronts the Audit Risk Model as incorporated in International Standard on Auditing No. 400, with the real life situations faced by auditors in auditing financial statements. This confrontation exposes ser

  6. Tests of control in the Audit Risk Model : Effective? Efficient?

    NARCIS (Netherlands)

    Blokdijk, J.H. (Hans)

    2004-01-01

    Lately, the Audit Risk Model has been subject to criticism. To gauge its validity, this paper confronts the Audit Risk Model as incorporated in International Standard on Auditing No. 400, with the real life situations faced by auditors in auditing financial statements. This confrontation exposes ser

  7. Tests of control in the Audit Risk Model : Effective? Efficient?

    NARCIS (Netherlands)

    Blokdijk, J.H. (Hans)

    2004-01-01

    Lately, the Audit Risk Model has been subject to criticism. To gauge its validity, this paper confronts the Audit Risk Model as incorporated in International Standard on Auditing No. 400, with the real life situations faced by auditors in auditing financial statements. This confrontation exposes

  8. Toward Self-Referential Autonomous Learning of Object and Situation Models.

    Science.gov (United States)

    Damerow, Florian; Knoblauch, Andreas; Körner, Ursula; Eggert, Julian; Körner, Edgar

    Most current approaches to scene understanding lack the capability to adapt object and situation models to behavioral needs not anticipated by the human system designer. Here, we give a detailed description of a system architecture for self-referential autonomous learning which enables the refinement of object and situation models during operation in order to optimize behavior. This includes structural learning of hierarchical models for situations and behaviors that is triggered by a mismatch between expected and actual action outcome. Besides proposing architectural concepts, we also describe a first implementation of our system within a simulated traffic scenario to demonstrate the feasibility of our approach.

  9. Grade 3 Students' Mathematization through Modeling: Situation Models and Solution Models with Mutli-Digit Subtraction Problem Solving

    Science.gov (United States)

    Murata, Aki; Kattubadi, Sailaja

    2012-01-01

    In considering mathematics problem solving as a model-eliciting activity (Lesh & Doerr, 2003; Lesh & Harel, 2003; Lesh & Zawojewski, 2008), it is important to know "what" students are modeling for the problems: situations or solutions. This study investigated Grade 3 students' mathematization process by examining how they modeled different…

  10. Communication patterns and satisfaction levels in three-dimensional versus real-life intimate relationships.

    Science.gov (United States)

    Gilbert, Richard L; Murphy, Nora A; Ávalos, M Clementina

    2011-10-01

    The present study compared communication patterns and satisfaction levels between three-dimensional (3D) and real-life intimate relationships using a sample of 71 participants who were concurrently involved in an intimate relationship within Second Life and a separate real-life romantic relationship. Participants indicated that the quality of their communication was significantly better in their Second-Life relationship and that they experienced higher levels of satisfaction with their virtual partners. The more positive or idealized view of the 3D relationships may have been due to higher levels of focused interaction and reduced stressors in the virtual world and the greater length, and associated problems, in participant's real-life relationships. In addition, the presence of a concurrent relationship within Second Life could have negatively affected participant's judgments of their real-life relationships. These data offer the first detailed assessment of communication patterns and satisfaction levels in intimate relationships across the real and 3D virtual realms as the number of users and romantic partners in immersive virtual environments continue to grow.

  11. Children with Imaginary Companions Focus on Mental Characteristics When Describing Their Real-life Friends

    Science.gov (United States)

    Davis, Paige E.; Meins, Elizabeth; Fernyhough, Charles

    2014-01-01

    Relations between having an imaginary companion (IC) and (i) descriptions of a real-life friend, (ii) theory of mind performance, and (iii) reported prosocial behaviour and behavioural difficulties were investigated in a sample of 5-year-olds (N?=?159). Children who had an IC were more likely than their peers without an IC to describe their best…

  12. Real life adherence of chronic hepatitis B patients to entecavir treatment

    NARCIS (Netherlands)

    van Vlerken, Lotte G; Arends, Pauline; Lieveld, Faydra I; Arends, Joop E; Brouwer, Willem Pieter; Siersema, Peter D; Janssen, Harry L; van Erpecum, KJ

    BACKGROUND: Real-life prospective data on adherence to nucleos(t)ide analogues in chronic hepatitis B patients are scarce. AIMS: We investigated adherence to entecavir in relation to virological response. METHODS: In this prospective study, we provided 100 consecutive chronic hepatitis B patients

  13. Real life adherence of chronic hepatitis B patients to entecavir treatment

    NARCIS (Netherlands)

    Vlerken, L.G. Van; Arends, P.; Lieveld, F.I.; Arends, J.E.; Brouwer, W.P.; Siersema, P.D.; Janssen, H.L.; Erpecum, K.J. van

    2015-01-01

    BACKGROUND: Real-life prospective data on adherence to nucleos(t)ide analogues in chronic hepatitis B patients are scarce. AIMS: We investigated adherence to entecavir in relation to virological response. METHODS: In this prospective study, we provided 100 consecutive chronic hepatitis B patients

  14. Contextualizing Performances: Comparing Performances during TOEFL iBT™ and Real-Life Academic Speaking Activities

    Science.gov (United States)

    Brooks, Lindsay; Swain, Merrill

    2014-01-01

    In this study we compare test takers' performance on the Speaking section of the TOEFL iBT™and their performances during their real-life academic studies. Thirty international graduate students from mixed language backgrounds in two different disciplines (Sciences and Social Sciences) responded to two independent and four integrated speaking tasks…

  15. Engineers and the Web: an analysis of real life gaps in information usage

    NARCIS (Netherlands)

    Kraaijenbrink, Jeroen

    2007-01-01

    Engineers face a wide range of gaps when trying to identify, acquire, and utilize information from the Web. To be able to avoid creating such gaps, it is essential to understand them in detail. This paper reports the results of a study of the real life gaps in information usage processes of 17 engin

  16. Motion Pictures and Real-Life Violence; What the Research Says.

    Science.gov (United States)

    Schramm, Wilbur

    There is evidence that violence in motion pictures viewed by children on screen or television can contribute to violence in real life, although the movies can rarely be blamed as the sole cause of anti-social conduct. Clinical reports cite instances of the effect on "susceptible" youngsters; e.g., emotionally disturbed individuals. Long-term…

  17. The Impossibility of "Real-Life" Word Problems (According to Bakhtin, Lacan, Zizek and Baudrillard)

    Science.gov (United States)

    Gerofsky, Susan

    2010-01-01

    In recent years a great deal of work on mathematical word problems has focused on efforts to bring more of "real life" into the problems themselves and students' uptake of these problems. Following on from earlier studies of the word problem as a pedagogical and literary genre, the author argues that we cannot unproblematically assume an ability…

  18. A Real-Life Based Evaluation Method of Deployable Vulnerable Road User Protection Systems

    NARCIS (Netherlands)

    Fredriksson, R.; Dahlgren, M.; Schijndel-de Nooij, M. van; Hair-Buijssen, S.H.H.M. de; Montfort, S. van

    2014-01-01

    Objective: The aim of this study was to develop a real-life-based evaluation method, incorporating vulnerable road user (VRU) full-body loading to a vehicle with a deployable protection system in relevant test setups, and use this method to evaluate a prototype pedestrian and cyclist protection syst

  19. Group Creativity Development by Solving Real-life Project in Engineering Education

    DEFF Research Database (Denmark)

    Zhou, Chunfang; Kolmos, Anette; Du, Xiangyun

    2011-01-01

    In recent years, problem and project based learning (PBL) has been employed by a growing number of educational institutions to foster creative engineers. Among the diverse pedagogical practices of PBL, there has been an emergence of real-life project for students. Based on literature of creativit...

  20. Contextualizing Performances: Comparing Performances during TOEFL iBT™ and Real-Life Academic Speaking Activities

    Science.gov (United States)

    Brooks, Lindsay; Swain, Merrill

    2014-01-01

    In this study we compare test takers' performance on the Speaking section of the TOEFL iBT™and their performances during their real-life academic studies. Thirty international graduate students from mixed language backgrounds in two different disciplines (Sciences and Social Sciences) responded to two independent and four integrated speaking tasks…

  1. A novel dataset for real-life evaluation of facial expression recognition methodologies

    NARCIS (Netherlands)

    Siddiqi, Muhammad Hameed; Ali, Maqbool; Idris, Muhammad; Banos, Oresti; Lee, Sungyoung; Choo, Hyunseung

    2016-01-01

    One limitation seen among most of the previous methods is that they were evaluated under settings that are far from real-life scenarios. The reason is that the existing facial expression recognition (FER) datasets are mostly pose-based and assume a predefined setup. The expressions in these datasets

  2. A savings based method for real-life vehicle routing problems

    NARCIS (Netherlands)

    A. Poot; G. Kant; A.P.M. Wagelmans (Albert)

    1999-01-01

    textabstractThis paper describes a Savings Based algorithm for the Extended Vehicle Routing Problem. This algorithm is compared with a Sequential Insertion algorithm on real-life data. Besides the traditional quality measures such as total distance traveled and total workload, we compare the routing

  3. Opportunities for real-life respiratory research in Korea: The HIRA database and beyond

    NARCIS (Netherlands)

    Van Boven, Job F.M.; Rhee, Chin-Kook; Park, Hae-Yun; Yoo, Kwang H.; Kim, Dong-Kyu; Soriano, Joan; Ming, Simon Wan Yau; Price, David; Park, Hae Sim

    2016-01-01

    Background: To date, most real-life respiratory research has been conducted using databases from Europe and North America. However, over half of the World population suffering from asthma or chronic obstructive pulmonary disease (COPD) are living outside these areas, limiting generalizability of

  4. Girls Involved in Real Life Sharing: Utilizing Technology to Support the Emotional Development of Teenaged Girls

    Science.gov (United States)

    Daily, Shaundra B.; Picard, Rosalind W.

    2007-01-01

    This paper describes a new digital technology to support emotional self-awareness and empathy, called G.I.R.L.S (Girls Involved in Real Life Sharing). The system invited users to reflect actively upon and interact with a dialogue about how the story made them feel through the construction of pictorial narratives. In a pilot study with teenage…

  5. Violence exposure in real-life, video games, television, movies, and the internet: is there desensitization?

    Science.gov (United States)

    Funk, Jeanne B; Baldacci, Heidi Bechtoldt; Pasold, Tracie; Baumgardner, Jennifer

    2004-02-01

    It is believed that repeated exposure to real-life and to entertainment violence may alter cognitive, affective, and behavioral processes, possibly leading to desensitization. The goal of the present study was to determine if there are relationships between real-life and media violence exposure and desensitization as reflected in related characteristics. One hundred fifty fourth and fifth graders completed measures of real-life violence exposure, media violence exposure, empathy, and attitudes towards violence. Regression analyses indicated that only exposure to video game violence was associated with (lower) empathy. Both video game and movie violence exposure were associated with stronger proviolence attitudes. The active nature of playing video games, intense engagement, and the tendency to be translated into fantasy play may explain negative impact, though causality was not investigated in the present design. The samples' relatively low exposure to real-life violence may have limited the identification of relationships. Although difficult to quantify, desensitization to violence should be further studied using related characteristics as in the present study. Individual differences and causal relationships should also be examined.

  6. Consumer Responses to the Carbon Labelling of Food: A Real Life Experiment in a Canteen Practice

    NARCIS (Netherlands)

    Spaargaren, G.; Koppen, van C.S.A.; Janssen, A.M.; Hendriksen, A.; Kolfschoten, C.J.

    2013-01-01

    The emerging debate on the climate impact of food is expected to result in the carbon labelling of food in the future. As yet, consumer responses to carbon labels are not well researched. A real life experiment was developed to study consumer responses to new carbon labels for food. A ‘light’ and a

  7. Bringing Reality into Calculus Classrooms: Mathematizing a Real-life Problem Simulated in a Virtual Environment

    Directory of Open Access Journals (Sweden)

    Olga V. Shipulina

    2013-01-01

    Full Text Available The study explores how students, who had completed the AP calculus course, mathematized the optimal navigation real-life problem simulated in the Second Life Virtual Environment. The particular research interest was to investigate whether/how students’ empirical activity in VE influences the way of their mathematizing.

  8. Real Life

    Institute of Scientific and Technical Information of China (English)

    王学文

    2004-01-01

    This month we are saying goodbye to a valued member of our team. Professor Bao Shixiu, who has been our proofreader for the last four years, is leaving us due to various reasons. Professor Bao's thorough knowledge and understanding of Chinese economy andsociety, combined with his excellent English skills, has held the magazine in good stead

  9. Implications of the Situated Learning Model for Teaching and Learning Nursing Research.

    Science.gov (United States)

    Gieselman, Janet A.; Stark, Nola; Farruggia, Michael J.

    2000-01-01

    A situated learning model was applied in a workshop on nursing research in order to provide a multifaceted, engaging learning experience. Techniques used included stories, reflection, cognitive apprenticeship, collaboration, coaching, multiple practice, articulation of learning skills, and technology. (SK)

  10. Immunosuppressive Drug Discontinuation in Noninfectious Uveitis From Real-Life Clinical Practice: A Survival Analysis.

    Science.gov (United States)

    Abásolo, Lydia; Rosales, Zulema; Díaz-Valle, David; Gómez-Gómez, Alejandro; Peña-Blanco, Rayma C; Prieto-García, Ángela; Benítez-Del-Castillo, José Manuel; Pato, Esperanza; García-Feijoo, Julián; Fernández-Gutiérrez, Benjamín; Rodriguez-Rodriguez, Luis

    2016-09-01

    To assess in uveitis patients the rate of immunosuppressive drug (ISD) discontinuation in real-life clinical practice, comparing this rate among ISDs. Longitudinal retrospective cohort study. We included uveitis patients attending a tertiary eye referral center from Madrid (Spain) between 1989 and 2015, prescribed any ISDs (cyclosporine, methotrexate, azathioprine, anti-TNF drugs, or others). Our main outcome was discontinuation of all ISDs owing to clinical efficacy, inefficacy, adverse drug reaction (ADR), and other medical causes. Discontinuation rates (DRs) per 100 patient-years were estimated. Variables associated with specific-cause discontinuations were analyzed using Cox bivariate and multivariate models. We analyzed 110 patients with 263 treatment courses and 665.2 patient-years of observation. Cyclosporine (66.4%), methotrexate (47.3%), azathioprine (30.9%), and anti-TNFs (30.9%) were the most frequently used ISDs. Treatment was suspended in 136 cases (mostly owing to clinical efficacy [38.2%], inefficacy [26.5%], and ADRs [22.8%]). All-cause DR with 95% confidence interval was 20.4 [17.3-24.2]. Retention rates at 1 and 10 years were 74% and 16%, respectively. In the multivariate analysis, combined treatment exhibited higher DRs owing to clinical efficacy than other ISDs in monotherapy. Conversely, nonbiologic combination therapy with azathioprine exhibited the highest DR owing to ADRs. Clinical efficacy was the most frequent cause for ISD discontinuation, followed by inefficacy and ADRs. DR owing to efficacy was higher for combination therapy. Furthermore, nonbiologic combination therapy with azathioprine was associated with a higher DR owing to ADRs. Copyright © 2016 Elsevier Inc. All rights reserved.

  11. Models of political public relations: Testing the situation in Catalonia

    Directory of Open Access Journals (Sweden)

    Dr. Jordi Xifra Triadú

    2008-01-01

    Full Text Available The idea that political communication strategies are an application of marketing strategies to political field is today commonly shared by specialists. For them public relations is viewed like a set of techniques that serves political parties and other actors of the political scene, concentrated on media relations. This instrumental perspective is not in keeping with structural dimension of public relations in political activity and communication of his actors: political parties, pressure groups and political leaders. In this point of view, during managing periods of governance or opposition and during electoral campaigns, the most applied communication form by political parties is structured in accordance with the major public relations models: press agent model, public information model, two way asymmetrical model, and two way symmetrical model. This research prove hypothesis in Catalonia according the results of a quantitative survey focused on inside professionals who provide services for the seven main political parties in this Spanish Autonomous Community.RESUMEN:La idea de que las estrategias de comunicación política constituyen una aplicación de las estrategias del marketing al ámbito político es hoy comúnmente compartida por los analistas. Para éstos, las relaciones públicas son percibidas como un conjunto de técnicas al servicio de los partidos políticos y de otros actores de la escena política concentradas en las relaciones con la prensa. Esta perspectiva instrumental no concuerda con la dimensión estructural de las relaciones públicas en la actividad política y comunicativa de sus actores: partidos políticos, grupos de presión y líderes. Desde este punto de vista, tanto en los periodos de gestión u oposición como en los electorales, la forma comunicativa más aplicada por los partidos políticos se estructura de acuerdo con los modelos tradicionales de las relaciones públicas: agente de prensa, información p

  12. Power requirements and environmental impact of a pedelec. A case study based on real-life applications

    Energy Technology Data Exchange (ETDEWEB)

    Abagnale, Carmelina, E-mail: c.abagnale@unina.it; Cardone, Massimo, E-mail: massimo.cardone@unina.it; Iodice, Paolo, E-mail: paolo.iodice@unina.it; Strano, Salvatore, E-mail: salvatore.strano@unina.it; Terzo, Mario, E-mail: m.terzo@unina.it; Vorraro, Giovanni, E-mail: giovanni.vorraro@unina.it

    2015-07-15

    This paper describes the methodologies to appraise the power requests and environmental analysis of an electrically assisted bicycle under real driving conditions, also containing regulations and technical-science-related aspects. For this purpose, in this study, the on-road test program of an electrically assisted bicycle was executed in the urban area of Naples on different test tracks, so a general assessment about its driving behavior under several driving conditions was performed. The power requirements in different typical riding situations were estimated by a procedure based on the experimental kinematic parameters that characterize the driving dynamics collected during the real-life applications. An environmental analysis was also performed, with a methodology that takes into account the environmental assessment of a moped by measuring the experimental moped exhaust emissions of the regulated pollutants. Starting from the results acquired during the different test samples, besides, an assessment of the electric traction offered by this pedelec on the driving comfort was evaluated for different riding situations. - Highlights: • The power requirements of a pedelec in typical riding conditions were identified. • The estimated electricity consumption for battery recharging was defined. • An environmental valuation of the tested pedelec and of a moped was performed. • Emissions that could be saved utilizing a pedelec instead of a moped were derived.

  13. Situational Consultation

    Science.gov (United States)

    Rimehaug, Tormod; Helmersberg, Ingunn

    2010-01-01

    Situational Consultation (SC) is presented as a framework for flexible integration of several models and methodologies in consultation practice by choosing an approach adapted to the specific situation. In SC, models and their characteristic role positions are considered interchangeable tools with qualitative differences in strengths and…

  14. The explosion at institute: modeling and analyzing the situation awareness factor.

    Science.gov (United States)

    Naderpour, Mohsen; Lu, Jie; Zhang, Guangquan

    2014-12-01

    In 2008 a runaway chemical reaction caused an explosion at a methomyl unit in West Virginia, USA, killing two employees, injuring eight people, evacuating more than 40,000 residents adjacent to the facility, disrupting traffic on a nearby highway and causing significant business loss and interruption. Although the accident was formally investigated, the role of the situation awareness (SA) factor, i.e., a correct understanding of the situation, and appropriate models to maintain SA, remain unexplained. This paper extracts details of abnormal situations within the methomyl unit and models them into a situational network using dynamic Bayesian networks. A fuzzy logic system is used to resemble the operator's thinking when confronted with these abnormal situations. The combined situational network and fuzzy logic system make it possible for the operator to assess such situations dynamically to achieve accurate SA. The findings show that the proposed structure provides a useful graphical model that facilitates the inclusion of prior background knowledge and the updating of this knowledge when new information is available from monitoring systems.

  15. The Effect of Television-Mediated Aggression and Real-Life Aggression on the Behavior of Lebanese Children.

    Science.gov (United States)

    Day, Richard C.; Ghandour, Maryam

    1984-01-01

    Investigates the effect of television-mediated aggression and real-life aggression on the behavior of Lebanese children. Observations made of 48 boys and 48 girls six to eight years of age revealed that boys as a group were more aggressive than girls and exhibited more imitative aggression. Girls were more violent after viewing real-life violence.…

  16. Studying the Classroom Implementation of Tasks: High-Level Mathematical Tasks Embedded in "Real-Life" Contexts

    Science.gov (United States)

    Stylianides, Andreas J.; Stylianides, Gabriel J.

    2008-01-01

    Mathematical tasks embedded in real-life contexts have received increased attention by educators, in part due to the considerable levels of student engagement often triggered by their motivational features. Nevertheless, it is often challenging for teachers to implement high-level (i.e., cognitively demanding), real-life tasks in ways that exploit…

  17. Revising Working Models Across Time: Relationship Situations That Enhance Attachment Security.

    Science.gov (United States)

    Arriaga, Ximena B; Kumashiro, Madoka; Simpson, Jeffry A; Overall, Nickola C

    2017-06-01

    We propose the Attachment Security Enhancement Model (ASEM) to suggest how romantic relationships can promote chronic attachment security. One part of the ASEM examines partner responses that protect relationships from the erosive effects of immediate insecurity, but such responses may not necessarily address underlying insecurities in a person's mental models. Therefore, a second part of the ASEM examines relationship situations that foster more secure mental models. Both parts may work in tandem. We posit that attachment anxiety should decline most in situations that foster greater personal confidence and more secure mental models of the self. In contrast, attachment avoidance should decline most in situations that involve positive dependence and foster more secure models of close others. The ASEM integrates research and theory, suggests novel directions for future research, and has practical implications, all of which center on the idea that adult attachment orientations are an emergent property of close relationships.

  18. Validation of Models : Statistical Techniques and Data Availability

    NARCIS (Netherlands)

    Kleijnen, J.P.C.

    1999-01-01

    This paper shows which statistical techniques can be used to validate simulation models, depending on which real-life data are available. Concerning this availability three situations are distinguished (i) no data, (ii) only output data, and (iii) both input and output data. In case (i) - no real

  19. Modeling and simulating command and control for organizations under extreme situations

    CERN Document Server

    Moon, Il-Chul; Kim, Tag Gon

    2013-01-01

    Commanding and controlling organizations in extreme situations is a challenging task in military, intelligence, and disaster management. Such command and control must be quick, effective, and considerate when dealing with the changing, complex, and risky conditions of the situation. To enable optimal command and control under extremes, robust structures and efficient operations are required of organizations. This work discusses how to design and conduct virtual experiments on resilient organizational structures and operational practices using modeling and simulation. The work illustrates key a

  20. A robust optimization model for blood supply chain in emergency situations

    OpenAIRE

    Meysam Fereiduni; Kamran Shahanaghi

    2016-01-01

    In this paper, a multi-period model for blood supply chain in emergency situation is presented to optimize decisions related to locate blood facilities and distribute blood products after natural disasters. In disastrous situations, uncertainty is an inseparable part of humanitarian logistics and blood supply chain as well. This paper proposes a robust network to capture the uncertain nature of blood supply chain during and after disasters. This study considers donor points, blood facilities,...

  1. Social anxiety in online and real-life interaction and their associated factors.

    Science.gov (United States)

    Yen, Ju-Yu; Yen, Cheng-Fang; Chen, Cheng-Sheng; Wang, Peng-Wei; Chang, Yi-Hsin; Ko, Chih-Hung

    2012-01-01

    Social anxiety was compared between online and real-life interaction in a sample of 2,348 college students. Severity of social anxiety in both real-life and online interaction was tested for associations with depression, Internet addiction, Internet activity type (gaming versus chatting), and scores on Behavioral Inhibition System (BIS)/Behavioral Activation System (BAS) scales. The results showed that social anxiety was lower when interacting online than when interacting offline. Depression, Internet addiction, and high BIS and BAS scores were associated with high social anxiety. The social anxiety decreased more in online interaction among subjects with high social anxiety, depression, BIS, and BAS. This result suggests that the Internet has good potential as an alternative medium for delivering interventions for social anxiety. Further, the effect of BIS on social anxiety is decreased in online interaction. More attention should be paid for BIS when the treatment for social anxiety is delivered online.

  2. Assessing the Value of Real-life Brands in Virtual Worlds

    DEFF Research Database (Denmark)

    Mattsson, Jan; Barnes, Stuart; Hartley, Nicole

    2015-01-01

    Virtual Worlds are a significant new market environment for brand-building through experiential customer service interactions. Using value theory, this paper aims to assess the experiential brand value of real-life brands that have moved to the Virtual World of Second Life. A key premise...... is that current brand offerings in Virtual Worlds do not offer consumers adequate experiential value. The results demonstrate both the validity of an axiological approach to examining brand value, and highlight significant problems in consumer perceptions of the experiential value of brands within the Virtual...... World. A key finding is the difficulty in creating emotional brand value in Second Life which has serious implications for the sustainability of current real-life brands in Virtual Worlds. The paper rounds off with conclusions and implications for future research and practice in this very new area....

  3. The Spelling Bee and Me: A Real-Life Adventure in Learning

    Science.gov (United States)

    Small, Gail; Yoshinaga, Kendra

    2006-01-01

    This book documents the real-life story of Kendra Yoshinaga, a young speller who won her first qualifying bee at the young age of nine. Now eleven years old, she is preparing for future events after tying for 27th in the 2004 National Spelling Bee. Gail Small, author of Joyful Learning: No One Ever Wants To Go To Recess!, taught Kendra for first,…

  4. A savings based method for real-life vehicle routing problems

    OpenAIRE

    1999-01-01

    textabstractThis paper describes a Savings Based algorithm for the Extended Vehicle Routing Problem. This algorithm is compared with a Sequential Insertion algorithm on real-life data. Besides the traditional quality measures such as total distance traveled and total workload, we compare the routing plans of both algorithms according to non-standard quality measures that help to evaluate the "visual attractiveness" of the plan. Computational results show that, in general, the Savings Based al...

  5. Using What's Learned in the Game for Use in Real Life.

    Science.gov (United States)

    Baranowski, Moderator Tom; Fiellin, Participants Lynn E; Gay, Geri; Thompson, Deborah I

    2014-02-01

    A player can learn many things from playing a game for health. Some of these learnings were deliberately designed for the player to use in his or her real life, outside of any game. The effective ways to enable players to generalize what they learn in the game to their real lives (and thereby benefit from playing the game) are not clear. We have convened a group of expert health game designers and researchers to discuss this important issue.

  6. Idiopathic pulmonary fibrosis: from clinical trials to real-life experiences

    Directory of Open Access Journals (Sweden)

    Sergio Harari

    2015-09-01

    Full Text Available Randomised controlled clinical trials are fundamental in medicine to develop new effective drugs and new therapeutic regimens and are the strength of evidence-based medicine. These studies allow us to avoid the repetition of misleading experiences that have been reported in the past, where drugs or associations were utilised without compelling evidence and ultimately proven to be ineffective. In recent years, randomised clinical trials have been conducted and concluded for many rare diseases, including idiopathic pulmonary fibrosis. However, clinical trials do not always reflect the real-life scenario. Patients selected for clinical trials present fewer comorbidities, they fall between certain age limits, and the severity of their disease is defined; therefore, they do not always reflect the whole of the population affected by a specific disease. These are the reasons why we also need data that mirror real-life experience. The limitations that these kind of studies present are always several and the studies should be interpreted with caution, although they can fill the important gap between efficacy and effectiveness. In this article, we will review the existing clinical data on real-life treatment of idiopathic pulmonary fibrosis.

  7. Acoustic Coordinated Reset Neuromodulation in a Real Life Patient Population with Chronic Tonal Tinnitus

    Directory of Open Access Journals (Sweden)

    Christian Hauptmann

    2015-01-01

    Full Text Available Purpose. Primary tinnitus has a severe negative influence on the quality of life of a significant portion of the general population. Acoustic coordinated reset neuromodulation is designed to induce a long-lasting reduction of tinnitus symptoms. To test acoustic coordinated reset neuromodulation as a treatment for chronic, tonal tinnitus under real life conditions, an outpatient study “RESET Real Life” was commissioned by ANM GmbH. Herein we present the results of this study. Methods. In a prospective, open-label, nonrandomized, noncontrolled multicenter clinical study with 200 chronic tinnitus patients, tinnitus questionnaire TBF-12 and Global Clinical Improvement-Impression Scale (CGI-I7 are used to study the safety and efficacy of acoustic coordinated reset neuromodulation. 189 patients completed the last 12-month visit, 11 patients dropped out (8 because of nontreatment related reasons; 2 because tinnitus did not change; and 1 because tinnitus got louder. Results. Acoustic coordinated reset neuromodulation caused a statistically and clinically significant decrease in TBF-12 scores as well as in CGI-I7 after 12 months of therapy under real life conditions. There were no persistent adverse events reported that were related to the therapy. Conclusion. The field study “RESET Real Life” provides evidence for safety and efficacy of acoustic coordinated reset neuromodulation in a prospective, open-label, real life setting.

  8. A queueing model of pilot decision making in a multi-task flight management situation

    Science.gov (United States)

    Walden, R. S.; Rouse, W. B.

    1977-01-01

    Allocation of decision making responsibility between pilot and computer is considered and a flight management task, designed for the study of pilot-computer interaction, is discussed. A queueing theory model of pilot decision making in this multi-task, control and monitoring situation is presented. An experimental investigation of pilot decision making and the resulting model parameters are discussed.

  9. A Novel Adaptive Grey Verhulst Model for Network Security Situation Prediction

    Directory of Open Access Journals (Sweden)

    Yu-Beng Leau

    2016-01-01

    Full Text Available Recently, researchers have shown an increased interest in predicting the situation of incoming security situation for organization’s network. Many prediction models have been produced for this purpose, but many of these models have various limitations in practical applications. In addition, literature shows that far too little attention has been paid in utilizing the grey Verhulst model predicting network security situation although it has demonstrated satisfactory results in other fields. By considering the nature of intrusion attacks and shortcomings of traditional grey Verhulst model, this paper puts forward an adaptive grey Verhust model with adjustable generation sequence to improve the prediction accuracy. The proposed model employs the combination methods of Trapezoidal rule and Simpson’s 1/3rd rule to obtain the background value in grey differential equation which will directly influence the forecast result. In order to verify the performance of the proposed model, benchmarked datasets, DARPA 1999 and 2000 have been used to highlight the efficacy of the proposed model. The results show that the proposed adaptive grey Verhulst surpassed GM(1,1 and traditional grey Verhulst in forecasting incoming security situation in a network.

  10. A Model of Distraction in an Audio-on-Audio Interference Situation with Music Program Material

    DEFF Research Database (Denmark)

    Francombe, J.; Mason, R.; Dewhirst, M.

    2015-01-01

    by a qualitative analysis of subject responses. Distraction ratings were collected for one hundred randomly created audio-on-audio interference situations with music target and interferer programs. The selected features were related to the overall loudness, loudness ratio, perceptual evaluation of audio source......There are many situations in which multiple audio programs are replayed over loudspeakers in the same acoustic environment, allowing listeners to focus on their desired target program. Where this situation is deliberately created and the different program items are centrally controlled, each...... listener can be viewed as having a personal sound zone system. In order to evaluate and optimize such situations in a perceptually relevant manner, the authors created a predictive model using the features that contribute to the distraction from unwanted sounds. Feature extraction was motivated...

  11. Application of a plume model for decision makers' situation awareness during an outdoor airborne HAZMAT release.

    Science.gov (United States)

    Meris, Ronald G; Barbera, Joseph A

    2014-01-01

    In a large-scale outdoor, airborne, hazardous materials (HAZMAT) incident, such as ruptured chlorine rail cars during a train derailment, the local Incident Commanders and HAZMAT emergency responders must obtain accurate information quickly to assess the situation and act promptly and appropriately. HAZMAT responders must have a clear understanding of key information and how to integrate it into timely and effective decisions for action planning. This study examined the use of HAZMAT plume modeling as a decision support tool during incident action planning in this type of extreme HAZMAT incident. The concept of situation awareness as presented by Endsley's dynamic situation awareness model contains three levels: perception, comprehension, and projection. It was used to examine the actions of incident managers related to adequate data acquisition, current situational understanding, and accurate situation projection. Scientists and engineers have created software to simulate and predict HAZMAT plume behavior, the projected hazard impact areas, and the associated health effects. Incorporating the use of HAZMAT plume projection modeling into an incident action plan may be a complex process. The present analysis used a mixed qualitative and quantitative methodological approach and examined the use and limitations of a "HAZMAT Plume Modeling Cycle" process that can be integrated into the incident action planning cycle. HAZMAT response experts were interviewed using a computer-based simulation. One of the research conclusions indicated the "HAZMAT Plume Modeling Cycle" is a critical function so that an individual/team can be tasked with continually updating the hazard plume model with evolving data, promoting more accurate situation awareness.

  12. Situated learning theory: adding rate and complexity effects via Kauffman's NK model.

    Science.gov (United States)

    Yuan, Yu; McKelvey, Bill

    2004-01-01

    For many firms, producing information, knowledge, and enhancing learning capability have become the primary basis of competitive advantage. A review of organizational learning theory identifies two approaches: (1) those that treat symbolic information processing as fundamental to learning, and (2) those that view the situated nature of cognition as fundamental. After noting that the former is inadequate because it focuses primarily on behavioral and cognitive aspects of individual learning, this paper argues the importance of studying learning as interactions among people in the context of their environment. It contributes to organizational learning in three ways. First, it argues that situated learning theory is to be preferred over traditional behavioral and cognitive learning theories, because it treats organizations as complex adaptive systems rather than mere information processors. Second, it adds rate and nonlinear learning effects. Third, following model-centered epistemology, it uses an agent-based computational model, in particular a "humanized" version of Kauffman's NK model, to study the situated nature of learning. Using simulation results, we test eight hypotheses extending situated learning theory in new directions. The paper ends with a discussion of possible extensions of the current study to better address key issues in situated learning.

  13. Rehabilitation in the real-life environment of a shopping mall.

    Science.gov (United States)

    Labbé, Delphine; Poldma, Tiiu; Fichten, Catherine; Havel, Alice; Kehayia, Eva; Mazer, Barbara; McKinley, Patricia; Rochette, Annie; Swaine, Bonnie

    2017-01-27

    The aim of this study was to explore how shopping malls could be used during rehabilitation and to identify the facilitators and barriers to their use. Two focus groups, conducted with 15 rehabilitation professionals from various disciplines and working with people with disabilities of all ages were structured around two topics: (i) The usage of malls for rehabilitation and (ii) Factors that facilitate or limit rehabilitation professionals' use of the mall as an environment for clinical assessment and/or intervention. The thematic analysis revealed that shopping malls were used to achieve several rehabilitation goals targeting physical and cognitive skills, psychological health and socialization. This real-life environment is motivating and helps foster independence and normalization. Factors affecting mall use during rehabilitation included personal factors (e.g. clients' personality and level of readiness) and environmental factors (e.g. clinical context, accessibility of the mall and social attitudes of store owners). Shopping malls may be a relevant rehabilitation assessment and treatment environment that could contribute to optimizing community integration of people with disabilities. Implications for rehabilitation To ensure successful community reintegration, clients could be trained at some point during their rehabilitation, to perform activities in real-life settings, such as a shopping mall. Shopping malls appear to enable the attainment of rehabilitation goals targeting a variety of skills. This real-life environment appears to be motivating and helps foster independence and normalization. Factors felt to affect mall use during rehabilitation include personal factors (e.g. clients' personality and level of readiness) and environmental factors (e.g. clinical context, accessibility of the mall and social attitudes of store owners). The shopping mall may be an untapped resource as it appears to be a relevant rehabilitation assessment and treatment

  14. The ways parents cope with stress in difficult parenting situations: the structural equation modeling approach

    Directory of Open Access Journals (Sweden)

    Agnieszka Szymańska

    2017-06-01

    Full Text Available The purpose of this study was to verify a theoretical model of parents’ responses to difficulties they experienced with their child. The model presents relationships between seven variables: (a discrepancy between parental goal and the child’s current level of development, (b parental experience of a difficulty, (c representation of the child in the parent’s mind, (d parent’s withdrawal from the parenting situation, (e seeking help, (f distancing oneself from the situation, and (g applying pressure on the child. The study involved 319 parents of preschool children: 66 parents of three-year-olds, 85 parents of four-year-olds, 99 parents of five-year-olds and 69 parents of six-year-old children. Structural equations modeling (SEM was used to verify the compounds described in the theoretical model. The studies revealed that when a parent is experiencing difficulties, the probability increases that the parent will have one of two reactions towards that type of stress: withdrawal from the situation or applying pressure on the child. Experiencing difficulties has no connection with searching for help and is negatively related to distancing oneself from the situation.

  15. Situational effects of the school factors included in the dynamic model of educational effectiveness

    NARCIS (Netherlands)

    Creerners, Bert; Kyriakides, Leonidas

    2009-01-01

    We present results of a longitudinal study in which 50 schools, 113 classes and 2,542 Cypriot primary students participated. We tested the validity of the dynamic model of educational effectiveness and especially its assumption that the impact of school factors depends on the current situation of th

  16. Training Inference Making Skills Using a Situation Model Approach Improves Reading Comprehension

    Directory of Open Access Journals (Sweden)

    Lisanne eBos

    2016-02-01

    Full Text Available This study aimed to enhance third and fourth graders’ text comprehension at the situation model level. Therefore, we tested a reading strategy training developed to target inference making skills, which are widely considered to be pivotal to situation model construction. The training was grounded in contemporary literature on situation model-based inference making and addressed the source (text-based versus knowledge-based, type (necessary versus unnecessary for (re-establishing coherence, and depth of an inference (making single lexical inferences versus combining multiple lexical inferences, as well as the type of searching strategy (forward versus backward. Results indicated that, compared to a control group (n = 51, children who followed the experimental training (n = 67 improved their inference making skills supportive to situation model construction. Importantly, our training also resulted in increased levels of general reading comprehension and motivation. In sum, this study showed that a ‘level of text representation’-approach can provide a useful framework to teach inference making skills to third and fourth graders.

  17. Training Inference Making Skills Using a Situation Model Approach Improves Reading Comprehension.

    Science.gov (United States)

    Bos, Lisanne T; De Koning, Bjorn B; Wassenburg, Stephanie I; van der Schoot, Menno

    2016-01-01

    This study aimed to enhance third and fourth graders' text comprehension at the situation model level. Therefore, we tested a reading strategy training developed to target inference making skills, which are widely considered to be pivotal to situation model construction. The training was grounded in contemporary literature on situation model-based inference making and addressed the source (text-based versus knowledge-based), type (necessary versus unnecessary for (re-)establishing coherence), and depth of an inference (making single lexical inferences versus combining multiple lexical inferences), as well as the type of searching strategy (forward versus backward). Results indicated that, compared to a control group (n = 51), children who followed the experimental training (n = 67) improved their inference making skills supportive to situation model construction. Importantly, our training also resulted in increased levels of general reading comprehension and motivation. In sum, this study showed that a 'level of text representation'-approach can provide a useful framework to teach inference making skills to third and fourth graders.

  18. Knowledge Structure Measures of Reader's Situation Models across Languages: Translation Engenders Richer Structure

    Science.gov (United States)

    Kim, Kyung; Clariana, Roy B.

    2015-01-01

    In order to further validate and extend the application of recent knowledge structure (KS) measures to second language settings, this investigation explores how second language (L2, English) situation models are influenced by first language (L1, Korean) translation tasks. Fifty Korean low proficient English language learners were asked to read an…

  19. Delft3D-FLOW on PRACE infrastructures for real life hydrodynamic applications.

    Science.gov (United States)

    Donners, John; Genseberger, Menno; Jagers, Bert; de Goede, Erik; Mourits, Adri

    2013-04-01

    PRACE, the Partnership for Advanced Computing in Europe, offers access to the largest high-performance computing systems in Europe. PRACE invites and helps industry to increase their innovative potential through the use of the PRACE infrastructure. This poster describes different efforts to assist Deltares with porting the open-source simulation software Delft3D-FLOW to PRACE infrastructures. Analysis of the performance on these infrastructures has been done for real life flow applications. Delft3D-FLOW is a 2D and 3D shallow water solver which calculates non-steady flow and transport phenomena resulting from tidal and meteorological forcing on a curvilinear, boundary fitted grid in Cartesian or spherical coordinates. It also includes a module which sediment transport (both suspended and bed total load) and morphological changes for an arbitrary number of cohesive and non-cohesive fractions. As Delft3D-FLOW has been developed over several decades, with a variety of functionality and over 350k lines of source code, porting to PRACE infrastructures needs some effort. At the moment Delft3D-FLOW uses MPI with domain decomposition in one direction as its parallellisation approach. Because it is hard to identify scaling issues if one immediately starts with a complex case with many features enabled, different cases with increasing complexity have been used to investigate scaling of this parallellisation approach on several PRACE platforms. As a base reference case we started with a schematic high-resolution 2D hydrodynamic model of the river Waal that turned out to be surprisingly well-suited to the highly-parallel PRACE machines. Although Delft3D-FLOW employs a sophisticated build system, several modifications were required to port it to most PRACE systems due to the use of specific, highly-tuned compilers and MPI-libraries. After this we moved to a 3D hydrodynamic model of Rotterdam harbour that includes sections of the rivers Rhine and Meuse and a part of the North

  20. An adaptation framework for turning Real-Life Events into Games

    DEFF Research Database (Denmark)

    Kjærhus Therkildsen, Sacha; Cassøe Bunkenborg, Nanna; Larsen, Lasse Juel

    method and participatory design to achieve our ambition. In conclusion we found that a framework for persuasive board games can be advanced by balancing five interrelated layers: 1) real life events (game fiction), 2) rules (formal game elements), 3) movement system (game mechanisms), 4) destiny......Many games are intended to change the players’ minds or actions. The presented design framework for persuasive board games is derived from the Syrian refugee crisis, which is used as backdrop to communicate the experience of being a refugee traveling through Europe. We applied an agile development...... (randomness), and 5) meaning (player choice) which prioritise game over story....

  1. Desiderio e scrittura in "The Real Life of Sebastian Knight" di Vladimir Nabokov

    Directory of Open Access Journals (Sweden)

    Valeria Invernizzi

    2014-12-01

    Full Text Available Questo articolo esamina l'intreccio di identità e scrittura nel romanzo nabokoviano The Real Life of Sebastian Knight (1941 da una prospettiva psicoanalitica, seguendo in particolare l'insegnamento di Freud e Lacan sul concetto di desiderio, significante e sublimazione artistica. L'attenzione principale sarà dedicata al rapporto tra i fratellastri, V. (il narratore e Sebastian. Dopo aver dimostrato che Sebastian Knight ha assunto il ruolo di oggetto del desiderio per chi lo ha conosciuto intimamente (soprattutto V., muovendo i personaggi secondo ciascun modo d'essere, si passerà al trauma della sua morte e all'elaborazione del lutto da parte del narratore, grazie alla creazione letteraria (la biografia fittizia che leggiamo; il paragrafo conclusivo analizza i cosiddetti 'inganni' del significante, episodi chiave in cui il narratore prende contatto con la verità del desiderio. Dato l'ineludibile interrogativo sulla paternità fittizia della Real Life (se l'autore fosse Sebastian Knight? e la questione del 'tocco artistico' di V., in questa argomentazione non verranno trascurati gli aspetti metaletterari dell'opera.  This paper examines from a psychoanalytic standpoint the intersection between identity and writing in the novel The Real Life of Sebastian Knight (1941 by Nabokov. In particular, in the wake of Freud’s and Lacan’s teaching, the following contribution will take as interpretative devices the notions of desire, signifier, and the process of sublimation involved in the artistic creation. Main focus of the analysis will be the relationship between the two half-brothers of the novel, V. (the narrator and Sebastian. First, I will show that Sebastian Knight holds the role of object of desire for the characters who had established a close relationship with him and, in particular, for V.; second, the paper will be devoted to the analysis of the trauma experienced by the char- acters because of V’s death, with a particular focus

  2. Real/Life: New British Art and the Reception of Contemporary British Art in Japan

    Directory of Open Access Journals (Sweden)

    Kajiya Kenji

    2016-07-01

    Full Text Available This essay explores the ways in which the exhibition Real/Life: New British Art was conceived and received in Japan, where contemporary British art has been shown since the 1960s. Taking place at five museums in the country between 1998 and 1999, the exhibition aimed to showhow British artists in the 1990s struggled with realities, internal and external, but its response was not as satisfactory as was expected. The essay examines the exhibition as a turning point for the transformation of exhibition culture in Japan from nationally themed exhibitions to showcases of contemporary art in the global context.

  3. 3D Projection on Physical Objects: Design Insights from Five Real Life Cases

    DEFF Research Database (Denmark)

    Dalsgaard, Peter; Halskov, Kim

    2011-01-01

    3D projection on physical objects is a particular kind of Augmented Reality that augments a physical object by projecting digital content directly onto it, rather than by using a mediating device, such as a mobile phone or a head- mounted display. In this paper, we present five cases in which we...... have developed installations that employ 3D projection on physical objects. The installations have been developed in collaboration with external partners and have been put into use in real-life settings such as museums, exhibitions and interaction design laboratories. On the basis of these cases, we...

  4. The situated HKB model: how sensorimotor spatial coupling can alter oscillatory brain dynamics.

    Science.gov (United States)

    Aguilera, Miguel; Bedia, Manuel G; Santos, Bruno A; Barandiaran, Xabier E

    2013-01-01

    Despite the increase of both dynamic and embodied/situated approaches in cognitive science, there is still little research on how coordination dynamics under a closed sensorimotor loop might induce qualitatively different patterns of neural oscillations compared to those found in isolated systems. We take as a departure point the Haken-Kelso-Bunz (HKB) model, a generic model for dynamic coordination between two oscillatory components, which has proven useful for a vast range of applications in cognitive science and whose dynamical properties are well understood. In order to explore the properties of this model under closed sensorimotor conditions we present what we call the situated HKB model: a robotic model that performs a gradient climbing task and whose "brain" is modeled by the HKB equation. We solve the differential equations that define the agent-environment coupling for increasing values of the agent's sensitivity (sensor gain), finding different behavioral strategies. These results are compared with two different models: a decoupled HKB with no sensory input and a passively-coupled HKB that is also decoupled but receives a structured input generated by a situated agent. We can precisely quantify and qualitatively describe how the properties of the system, when studied in coupled conditions, radically change in a manner that cannot be deduced from the decoupled HKB models alone. We also present the notion of neurodynamic signature as the dynamic pattern that correlates with a specific behavior and we show how only a situated agent can display this signature compared to an agent that simply receives the exact same sensory input. To our knowledge, this is the first analytical solution of the HKB equation in a sensorimotor loop and qualitative and quantitative analytic comparison of spatially coupled vs. decoupled oscillatory controllers. Finally, we discuss the limitations and possible generalization of our model to contemporary neuroscience and philosophy of

  5. The Situated HKB Model: how sensorimotor spatial coupling can alter oscillatory brain dynamics

    Directory of Open Access Journals (Sweden)

    Miguel eAguilera

    2013-08-01

    Full Text Available Despite the increase both of dynamic and embodied/situated approaches in cognitive science, there is still little research on how coordination dynamics under a closed sensorimotor loop might induce qualitatively different patterns of neural oscillations compared to those found in isolated systems. We take as a departure point the HKB model, a generic model for dynamic coordination between two oscillatory components, which has proven useful for a vast range of applications in cognitive science and whose dynamical properties are well understood. In order to explore the properties of this model under closed sensorimotor conditions we present what we call the situated HKB model: a robotic model that performs a gradient climbing task and whose "brain" is modelled by the HKB equation. We solve the differential equations that define the agent-environment coupling for increasing values of the agent's sensitivity (sensor gain, finding different behavioural strategies. These results are compared with two different models: a decoupled HKB with no sensory input and a passively-coupled HKB that is also decoupled but receives a structured input generated by a situated agent. We can precisely quantify and qualitatively describe how the properties of the system, when studied in coupled conditions, radically change in a manner that cannot be deduced from the decoupled HKB models alone. We also present the notion of neurodynamic signature as the dynamic pattern that correlates with a specific behaviour and we show how only a situated agent can display this signature compared to an agent that simply receives the exact same sensory input.To our knowledge, this is the first analytical solution of the HKB equation in a sensorimotor loop and qualitative and quantitative analytic comparison of spatially coupled vs. decoupled oscillatory controllers. Finally, we discuss the limitations and possible generalization of our model to contemporary neuroscience and philosophy

  6. Current situation for cultivating reflective thinking in English reading instruction--The influence of teaching models

    Institute of Scientific and Technical Information of China (English)

    Meng Qinglan

    2013-01-01

    Reflective thinking plays an essential role in cultivating students’creative ability. It’s essential to cultivate this ability in the process of reading instruction,while the present traditional English teaching models hinder its development. This paper tries to analyze the current situation in cultivating students’reflective thinking in English reading instruction from the traditional teaching models,in the hope of refreshing the teachers’consciousness on their teaching methods.

  7. Real-Life Impact of Executive Function Impairments in Adults Who Were Born Very Preterm.

    Science.gov (United States)

    Kroll, Jasmin; Karolis, Vyacheslav; Brittain, Philip J; Tseng, Chieh-En Jane; Froudist-Walsh, Sean; Murray, Robin M; Nosarti, Chiara

    2017-05-01

    Children and adolescents who were born very preterm (≤32 weeks' gestation) are vulnerable to experiencing cognitive problems, including in executive function. However, it remains to be established whether cognitive deficits are evident in adulthood and whether these exert a significant effect on an individual's real-lifeachievement. Using a cross-sectional design, we tested a range of neurocognitive abilities, with a focus on executive function, in a sample of 122 very preterm individuals and 89 term-born controls born between 1979 and 1984. Associations between executive function and a range of achievement measures, indicative of a successful transition to adulthood, were examined. Very preterm adults performed worse compared to controls on measures of intellectual ability and executive function with moderate to large effect sizes. They also demonstrated significantly lower achievement levels in terms of years spent in education, employment status, and on a measure of functioning in work and social domains. Results of regression analysis indicated a stronger positive association between executive function and real-life achievement in the very preterm group compared to controls. Very preterm born adults demonstrate executive function impairments compared to full-term controls, and these are associated with lower achievement in several real-life domains. (JINS, 2017, 23, 381-389).

  8. Conceptual Model of Business Situation of Attraction and Reproduction of Temporary Personnel of the Event Service

    Directory of Open Access Journals (Sweden)

    Donets Oleksiy S.

    2014-01-01

    Full Text Available The article considers importance of formation of the acting system of personnel management, since personnel determines the competitive potential and competitive advantages of an organisation. It develops a cognitive model of a business situation, which helps to present the process of attraction and reproduction of temporary personnel at enterprises, which deal with organisation of large-scale events, and influence of the factors upon each other. It builds a conceptual model of a business situation of attraction and reproduction of temporary personnel of the event service and, on its basis, offers a model of decision making with the use of elements of fuzzy logic on selection of a specialist for a specific position. It allocates main characteristics of employees, which are taken into account when forming decisions regarding taking on a candidate.

  9. Capacity building for tropical coastal ecosystems management using a dynamic teaching model

    DEFF Research Database (Denmark)

    Lindberg, Annika Büchert; Nielsen, Thomas; Macintosh, Donald

    2008-01-01

    This learning opportunity illustrates effective capacity building through a dynamic teaching model that involves you and gives you personal experiences. The teaching model is easy to adapt to local environments and the learning opportunity is relevant to everyone working in coastal natural resource...... the role play and hereby gain experience from a situation mimicking real life project situation.; The participants will experience how dynamic teaching can improve capacity building....

  10. Situated University, Situated Writing

    Science.gov (United States)

    Feldman, Ann M.

    2009-01-01

    This article argues that teaching as a situated, civic activity must be a core intellectual activity in the engaged metropolitan university. Situated writing provides the key pedagogy for the Chicago Civic Leadership Certificate Program at the University of Illinois at Chicago, an engaged public research university. The role of writing, or…

  11. The Evolution of a Connectionist Model of Situated Human Language Understanding

    Science.gov (United States)

    Mayberry, Marshall R.; Crocker, Matthew W.

    The Adaptive Mechanisms in Human Language Processing (ALPHA) project features both experimental and computational tracks designed to complement each other in the investigation of the cognitive mechanisms that underlie situated human utterance processing. The models developed in the computational track replicate results obtained in the experimental track and, in turn, suggest further experiments by virtue of behavior that arises as a by-product of their operation.

  12. A network security situation prediction model based on wavelet neural network with optimized parameters

    Directory of Open Access Journals (Sweden)

    Haibo Zhang

    2016-08-01

    Full Text Available The security incidents ion networks are sudden and uncertain, it is very hard to precisely predict the network security situation by traditional methods. In order to improve the prediction accuracy of the network security situation, we build a network security situation prediction model based on Wavelet Neural Network (WNN with optimized parameters by the Improved Niche Genetic Algorithm (INGA. The proposed model adopts WNN which has strong nonlinear ability and fault-tolerance performance. Also, the parameters for WNN are optimized through the adaptive genetic algorithm (GA so that WNN searches more effectively. Considering the problem that the adaptive GA converges slowly and easily turns to the premature problem, we introduce a novel niche technology with a dynamic fuzzy clustering and elimination mechanism to solve the premature convergence of the GA. Our final simulation results show that the proposed INGA-WNN prediction model is more reliable and effective, and it achieves faster convergence-speed and higher prediction accuracy than the Genetic Algorithm-Wavelet Neural Network (GA-WNN, Genetic Algorithm-Back Propagation Neural Network (GA-BPNN and WNN.

  13. Agent Based Modeling and Simulation of Pedestrian Crowds In Panic Situations

    KAUST Repository

    Alrashed, Mohammed

    2016-11-01

    The increasing occurrence of panic stampedes during mass events has motivated studying the impact of panic on crowd dynamics and the simulation of pedestrian flows in panic situations. The lack of understanding of panic stampedes still causes hundreds of fatalities each year, not to mention the scarce methodical studies of panic behavior capable of envisaging such crowd dynamics. Under those circumstances, there are thousands of fatalities and twice that many of injuries every year caused be crowd stampede worldwide, despite the tremendous efforts of crowd control and massive numbers of safekeeping forces. Pedestrian crowd dynamics are generally predictable in high-density crowds where pedestrians cannot move freely and thus gives rise to self-propelling interactions between pedestrians. Although every pedestrian has personal preferences, the motion dynamics can be modeled as a social force in such crowds. These forces are representations of internal preferences and objectives to perform certain actions or movements. The corresponding forces can be controlled for each individual to represent a different variety of behaviors that can be associated with panic situations such as escaping danger, clustering, and pushing. In this thesis, we use an agent-based model of pedestrian behavior in panic situations to predict the collective human behavior in such crowd dynamics. The proposed simulations suggests a practical way to alleviate fatalities and minimize the evacuation time in panic situations. Moreover, we introduce contagious panic and pushing behavior, resulting in a more realistic crowd dynamics model. The proposed methodology describes the intensity and spread of panic for each individual as a function of distances between pedestrians.

  14. Real life Dosages and Costs of TNFα inhibitor therapy for RA patients in Denmark

    DEFF Research Database (Denmark)

    Hostenkamp, Gisela; Sørensen, Jan; Hetland, Merete Lund

    2009-01-01

    about the true long run cost. Taking the actual medication practice into account is important for the evaluation of the costs and optimal sequencing of new and existing biological treatments. Objectives: To investigate the drug cost of TNF-inhibitors in the treatment of RA using real-life data from...... regime costs after the initiation period and increased with the number of treatment lines. Conclusion: The current consumption patterns of TNF-Inhibitors in Denmark indicate that the drug costs for adalimumab and etanercept are similar but exceed the drug costs for infliximab after the first year...... of treatment. Cost estimates based on short term observational data or on instruction leaflets from manufacturers may provide wrong cost assessments of TNF-alpha therapy. It is important to take the long term cost structure into account to arrive at unbiased treatment cost estimates....

  15. Cyberbullying in Germany – an exploration of prevalence, overlapping with real life bullying and coping strategies

    Directory of Open Access Journals (Sweden)

    JULIA RIEBEL

    2009-09-01

    Full Text Available A new phenomenon of violence among pupils has been spreading over Europe in the last few years: Cyberbullying, the repeated and intended hurting of weaker schoolmates via modern communication technologies. This study shows (based on a sample of 1987 pupils, that cyberbullying exists in Germany, although the number of incidents is still rather small. It could also be shown, that the pupils who act as cyberbullies are the same as those who bully others in real life. The same overlap was found to be true for the victims. Cyberbullying can therefore be considered a subcategory of ordinary bullying instead of being considered a whole new phenomenon. The exploration of coping strategies showed, that a common factor structure underlies physical, verbal and cyberbullying. Considering the fact that the findings of the study are based on an online questionnaire with restricted representativeness, the results should however be interpreted carefully.

  16. 3D Projection on Physical Objects: Design Insights from Five Real Life Cases

    DEFF Research Database (Denmark)

    Dalsgaard, Peter; Halskov, Kim

    2011-01-01

    3D projection on physical objects is a particular kind of Augmented Reality that augments a physical object by projecting digital content directly onto it, rather than by using a mediating device, such as a mobile phone or a head- mounted display. In this paper, we present five cases in which we...... have developed installations that employ 3D projection on physical objects. The installations have been developed in collaboration with external partners and have been put into use in real-life settings such as museums, exhibitions and interaction design laboratories. On the basis of these cases, we...... present and discuss three central design insights concerning new potentials for well-known 3D effects, dynamics between digital world and physical world, and relations between object, content and context....

  17. Evaluation of RPL-compliant routing solutions in real-life WSNs

    Directory of Open Access Journals (Sweden)

    Zahariadis Theodore

    2016-01-01

    Full Text Available Wireless Sensor Networks (WSN applications continue to expand and already cover almost all our daily activities improving from security and environmental efficiency to gaming experience. The diverse applications running on top of WSNs have led to the design of an immense number of routing protocols. Few years ago, the IETF standardized the IPv6 routing protocol for low-power and lossy networks (RPL which is based on routing metrics to build communication paths between a source and the destination node. While significant efforts have focused on the design of routing metrics that satisfy the various applications, limited work has been reported on validating their performance using real-life motes. In this paper, we focus on validating the simulation results (obtained through the JSim simulator using TelosB motes for a set of routing metrics that have been proposed in our previous articles.

  18. Group Creativity Development by Solving Real-life Project in Engineering Education

    DEFF Research Database (Denmark)

    Zhou, Chunfang; Kolmos, Anette; Du, Xiangyun

    2011-01-01

    creativity can be developed by the mutual function of the four dimensions under the positive facilitation of supervisors. A case study was carried out with a student satellite project in the department of electronic systems at Aalborg University in Denmark. Multiple methods including interviews......In recent years, problem and project based learning (PBL) has been employed by a growing number of educational institutions to foster creative engineers. Among the diverse pedagogical practices of PBL, there has been an emergence of real-life project for students. Based on literature of creativity...... research, PBL theories and the social theory of learning, this paper analyzes and discusses four major dimensions of project work - problem analysis and solving, group learning, interdisciplinary learning and project management - as the factors in constructing creative learning environments. We think group...

  19. Simulation to track 3D location in GSM through NS2 and real life

    CERN Document Server

    Gupta, Anand; Bosco, MS Don; Shashidhar, Vinay; 10.5121/jgraphhoc.2010.2103

    2010-01-01

    In recent times the cost of mobile communication has dropped significantly leading to a dramatic increase in mobile phone usage. The widespread usage has led mobiles to emerge as a strong alternative for other applications one of which is tracking. This has enabled law-enforcing agencies to detect overspeeding vehicles and organizations to keep track its employees. The 3 major ways of tracking being employed presently are (a) via GPS [1] (b) signal attenuation property of a packet [3] and (c) using GSM Network [2]. The initial cost of GPS is very high resulting in low usage whereas (b) needs a very high precision measuring device. The paper presents a GSM-based tracking technique which eliminates the above mentioned overheads, implements it in NS2 and shows the limitations of the real life simulation. An accuracy of 97% was achieved during NS2 simulation which is comparable to the above mentioned alternate methods of tracking.

  20. Nonlinear real-life signal detection with a supervised principal components analysis.

    Science.gov (United States)

    Zhou, C T; Cai, T X; Cai, T F

    2007-03-01

    A novel strategy named supervised principal components analysis for the detection of a target signal of interest embedded in an unknown noisy environment has been investigated. There are two channels in our detection scheme. Each channel consists of a nonlinear phase-space reconstructor (for embedding a data matrix using the received time series) and a principal components analyzer (for feature extraction), respectively. The output error time series, which results from the difference of both eigenvectors of the correlation data matrices from these two channels, is then analyzed using time-frequency tools, for example, frequency spectrum or Wigner-Ville distribution. Experimental results based on real-life electromagnetic data are presented to demonstrate the detection performance of our algorithm. It is found that weak signals hidden beneath the noise floor can be detected. Furthermore, the robustness of the detection performance clearly illustrated that signal frequencies can be extracted when the signal power is not too low.

  1. A robust optimization model for blood supply chain in emergency situations

    Directory of Open Access Journals (Sweden)

    Meysam Fereiduni

    2016-09-01

    Full Text Available In this paper, a multi-period model for blood supply chain in emergency situation is presented to optimize decisions related to locate blood facilities and distribute blood products after natural disasters. In disastrous situations, uncertainty is an inseparable part of humanitarian logistics and blood supply chain as well. This paper proposes a robust network to capture the uncertain nature of blood supply chain during and after disasters. This study considers donor points, blood facilities, processing and testing labs, and hospitals as the components of blood supply chain. In addition, this paper makes location and allocation decisions for multiple post disaster periods through real data. The study compares the performances of “p-robust optimization” approach and “robust optimization” approach and the results are discussed.

  2. Situated sentence processing: the coordinated interplay account and a neurobehavioral model.

    Science.gov (United States)

    Crocker, Matthew W; Knoeferle, Pia; Mayberry, Marshall R

    2010-03-01

    Empirical evidence demonstrating that sentence meaning is rapidly reconciled with the visual environment has been broadly construed as supporting the seamless interaction of visual and linguistic representations during situated comprehension. Based on recent behavioral and neuroscientific findings, however, we argue for the more deeply rooted coordination of the mechanisms underlying visual and linguistic processing, and for jointly considering the behavioral and neural correlates of scene-sentence reconciliation during situated comprehension. The Coordinated Interplay Account (CIA; Knoeferle, P., & Crocker, M. W. (2007). The influence of recent scene events on spoken comprehension: Evidence from eye movements. Journal of Memory and Language, 57(4), 519-543) asserts that incremental linguistic interpretation actively directs attention in the visual environment, thereby increasing the salience of attended scene information for comprehension. We review behavioral and neuroscientific findings in support of the CIA's three processing stages: (i) incremental sentence interpretation, (ii) language-mediated visual attention, and (iii) the on-line influence of non-linguistic visual context. We then describe a recently developed connectionist model which both embodies the central CIA proposals and has been successfully applied in modeling a range of behavioral findings from the visual world paradigm (Mayberry, M. R., Crocker, M. W., & Knoeferle, P. (2009). Learning to attend: A connectionist model of situated language comprehension. Cognitive Science). Results from a new simulation suggest the model also correlates with event-related brain potentials elicited by the immediate use of visual context for linguistic disambiguation (Knoeferle, P., Habets, B., Crocker, M. W., & Münte, T. F. (2008). Visual scenes trigger immediate syntactic reanalysis: Evidence from ERPs during situated spoken comprehension. Cerebral Cortex, 18(4), 789-795). Finally, we argue that the mechanisms

  3. A transactional framework for pediatric rehabilitation: shifting the focus to situated contexts, transactional processes, and adaptive developmental outcomes.

    Science.gov (United States)

    King, Gillian; Imms, Christine; Stewart, Debra; Freeman, Matt; Nguyen, Tram

    2017-04-11

    A paradigm shift is taking place in pediatric rehabilitation research, practice, and policy - a shift towards the real-life contexts of clients rather than requiring clients to navigate the world of pediatric rehabilitation. This article proposes a conceptual framework to bring about a broader awareness of clients' lives and transactional processes of change over the life course. The framework draws attention to transactional processes by which individuals, situated in life contexts, change and adapt over the life course and, in turn, influence their contextual settings and broader environments. This framework is based on (a) basic tenets derived from foundational theories taking a life course perspective to change, and (b) transactional processes identified from relevant pediatric rehabilitation models that bring these foundational theories into the pediatric rehabilitation sphere. The framework identifies three types of transactional processes relevant to pediatric rehabilitation: facilitative, resiliency, and socialization processes. These processes describe how contexts and people mutually influence each other via opportunities and situated experiences, thus facilitating capacity, adaptation to adversity, and socialization to new roles and life transitions. The utility of the framework is considered for research, practice, service organizations, and policy. Implications for Rehabilitation The framework supports practitioners going beyond person and environment as separate entities, to provide services to the "situated person" in real-life contexts The framework shifts the focus from "body structures/functions" and "person in activity" to "person in changing and challenging life contexts" Working from a transactional perspective, practitioner-client conversations will change; practitioners will view client situations through a lens of opportunities and experiences, assess client experiences in real-life contexts, and strive to create context-based therapy

  4. A Comparison of Online Social Networks and Real-Life Social Networks: A Study of Sina Microblogging

    Directory of Open Access Journals (Sweden)

    Dayong Zhang

    2014-01-01

    Full Text Available Online social networks appear to enrich our social life, which raises the question whether they remove cognitive constraints on human communication and improve human social capabilities. In this paper, we analyze the users' following and followed relationships based on the data of Sina Microblogging and reveal several structural properties of Sina Microblogging. Compared with real-life social networks, our results confirm some similar features. However, Sina Microblogging also shows its own specialties, such as hierarchical structure and degree disassortativity, which all mark a deviation from real-life social networks. The low cost of the online network forms a broader perspective, and the one-way link relationships make it easy to spread information, but the online social network does not make too much difference in the creation of strong interpersonal relationships. Finally, we describe the mechanisms for the formation of these characteristics and discuss the implications of these structural properties for the real-life social networks.

  5. Work situation operative model MOST: linking diagnosis and intervention to improve work conditions.

    Science.gov (United States)

    Morales, Karen Lange; García-Acosta, Gabriel; Urueña-Télleze, William; Pérez, Adriana

    2012-01-01

    This paper presents the model "Work Situation Operative Model" - MOST (after its Spanish acronym). It offers a comprehensive, systemic approach to analysing work stations and/or work processes, serving also as a framework for pursuing various ergonomic and occupational health and safety goals. Originally produced for a food sector company, the model has been extended and successfully applied in several industries in Colombia and Ecuador, including cement, oil, and paper industries. Based on a systemic understanding of work systems and tasks, the model not only allows different, commonly-used methods and tools for evaluating or assessing the risk of muscular-sketetal disorders to be included, but also supports occupational risk management strategies. Hence, one of its more important contributions relies on providing meaningful information that is useful for improving the work station and/or work process through design and re-design, by focusing on the interactions between all system elements.

  6. Evolutionistic or revolutionary paths? A PACS maturity model for strategic situational planning.

    Science.gov (United States)

    van de Wetering, Rogier; Batenburg, Ronald; Lederman, Reeva

    2010-07-01

    While many hospitals are re-evaluating their current Picture Archiving and Communication System (PACS), few have a mature strategy for PACS deployment. Furthermore, strategies for implementation, strategic and situational planning methods for the evolution of PACS maturity are scarce in the scientific literature. Consequently, in this paper we propose a strategic planning method for PACS deployment. This method builds upon a PACS maturity model (PMM), based on the elaboration of the strategic alignment concept and the maturity growth path concept previously developed in the PACS domain. First, we review the literature on strategic planning for information systems and information technology and PACS maturity. Secondly, the PMM is extended by applying four different strategic perspectives of the Strategic Alignment Framework whereupon two types of growth paths (evolutionistic and revolutionary) are applied that focus on a roadmap for PMM. This roadmap builds a path to get from one level of maturity and evolve to the next. An extended method for PACS strategic planning is developed. This method defines eight distinctive strategies for PACS strategic situational planning that allow decision-makers in hospitals to decide which approach best suits their hospitals' current situation and future ambition and what in principle is needed to evolve through the different maturity levels. The proposed method allows hospitals to strategically plan for PACS maturation. It is situational in that the required investments and activities depend on the alignment between the hospital strategy and the selected growth path. The inclusion of both strategic alignment and maturity growth path concepts make the planning method rigorous, and provide a framework for further empirical research and clinical practice.

  7. EXPERIMENTAL STUDIES ON DIFFICULTY OF EVACUATION FROM UNDERGROUND SPACES UNDER INUNDATED SITUATIONS USING REAL SCALE MODELS

    Science.gov (United States)

    Baba, Yasuyuki; Ishigaki, Taisuke; Toda, Keiichi; Nakagawa, Hajime

    Many urbanized cities in Japan are located in alluvial plains, and the vulnerability of urbanized areas to flood disaster is highlighted by flood attacks due to heavy rain fall or typhoons. Underground spaces located in the urbanized area are flood-prone areas, and the intrusion of flood watar into underground space inflicted severe damages on urban functions and infrastructures. In a similar way, low-lying areas like "bowl-shaped" depression and underpasses under highway and railroad bridges are also prone to floods. The underpasses are common sites of accidents of submerged vehicles, and severe damage including human damage occasionally occurs under flooding conditions. To reduce the damage due to inundation in underground space, needless to say, early evacuation is one of the most important countermeasures. This paper shows some experimental results of evacuation tests from underground spaces under inundated situations. The difficulities of the evacuation from underground space has been investigated by using real scale models (door, staircase and vehicle), and the limit for safety evacuation is discussed. From the results, it is found that water depth of 0.3 - 0.4m would be a critical situation for the evacuation from underground space through staircases and door and that 0.7 - 0.8m deep on the ground would be also a critical situation for safety evacuation though the doors of the vehicle. These criteria have some possibility to vary according to different inundated situations, and they are also influenced by the individual variation like the difference of physical strength. This means that these criteria requires cautious stance to use although they show a sort of an index of the limitation for saftty evacuation from underground space.

  8. Towards the measurement of event-related EEG activity in real-life working environments.

    Science.gov (United States)

    Wascher, Edmund; Heppner, Holger; Hoffmann, Sven

    2014-01-01

    In applied contexts, psychophysiological measures have a long tradition to evaluate the user state. EEG correlates that indicate mechanisms of information processing, however, are hardly accessible since discrete time stamps that are necessary for this approach are commonly not available in natural situations. However, eye blinks may close this gap. Eye blinks are assumed to mark distinct points in information processing, necessary to segment the incoming data stream. By using mobile EEG in a simulated working situation we demonstrate that eye-blink-related potentials provide reliable information about cognitive processing in distinct working environments. During cognitive tasks, an increase in the fronto-central N2 component as well as evoked theta activity can be shown, both indices of enhanced cognitive control. The posterior P3 is reduced during physical tasks (sorting of boxes), probably reflecting the more continuous nature of this task. The data are discussed within a model of dopaminergic modulation of blink activity that involves both task specific aspects like executive control and modulating influences of motivation or fatigue.

  9. Developing a Laboratory Model for the Professional Preparation of Future Science Teachers: A Situated Cognition Perspective

    Science.gov (United States)

    Sweeney, Aldrin E.; Paradis, Jeffrey A.

    2004-04-01

    Although laboratory activities are widely acknowledged as being fundamental to the teaching of science, many secondary science school teachers have limited knowledge of how to design and run effective teaching laboratories. Utilising a situated cognition theoretical framework, we discuss our collaborative efforts to develop a laboratory based model for the professional preparation of secondary level science teachers. Findings from the study suggest that the learning which occurs in the laboratory context may be transferred (with appropriate modifications) to the secondary science classroom. Implications also are presented for science teacher preparation, ongoing professional development, and further study.

  10. Cost sharing in production situations and network exploitation

    NARCIS (Netherlands)

    Koster, M.A.L.

    1999-01-01

    In many real-life situations where individuals work together in a joint project, joint costs (or profits) occur which have to be shared. The central problem of cost sharing is the allocation of costs in a 'just' way among the participants. Examples are numerous and range from setting fees for the us

  11. They fight because we let them! Applying a situational crime prevention model to barroom violence.

    Science.gov (United States)

    Graham, Kathryn

    2009-03-01

    This paper draws on situational crime prevention and social interactionist theories to develop a theoretical model for preventing aggression and injury in licensed drinking establishments. The model includes six components: (i) the presence of willing participants; (ii) the role of guardians, handlers and place managers; (iii) environmental deterrents of aggression; (iv) environmental precipitators of aggression; (v) theories regarding the effects of alcohol that contribute to increased risk of aggression; and (vi) social interaction theory relevant to the process of aggressive incidents in drinking establishments. The model provides a basis for developing a range of strategies to reduce barroom aggression that includes but is not restricted to addressing the role of alcohol. The paper discusses how these strategies can be developed and implemented through interventions, programs, policies or regulations at the level of the drinking establishment, the community level or the state/national level.

  12. Exploring English Language Learners (ELL) experiences with scientific language and inquiry within a real life context

    Science.gov (United States)

    Algee, Lisa M.

    English Language Learners (ELL) are often at a distinct disadvantage from receiving authentic science learning opportunites. This study explored English Language Learners (ELL) learning experiences with scientific language and inquiry within a real life context. This research was theoretically informed by sociocultural theory and literature on student learning and science teaching for ELL. A qualitative, case study was used to explore students' learning experiences. Data from multiple sources was collected: student interviews, science letters, an assessment in another context, field-notes, student presentations, inquiry assessment, instructional group conversations, parent interviews, parent letters, parent homework, teacher-researcher evaluation, teacher-researcher reflective journal, and student ratings of learning activities. These data sources informed the following research questions: (1) Does participation in an out-of-school contextualized inquiry science project increase ELL use of scientific language? (2) Does participation in an out-of-school contextualized inquiry science project increase ELL understanding of scientific inquiry and their motivation to learn? (3) What are parents' funds of knowledge about the local ecology and does this inform students' experiences in the science project? All data sources concerning students were analyzed for similar patterns and trends and triangulation was sought through the use of these data sources. The remaining data sources concerning the teacher-researcher were used to inform and assess whether the pedagogical and research practices were in alignment with the proposed theoretical framework. Data sources concerning parental participation accessed funds of knowledge, which informed the curriculum in order to create continuity and connections between home and school. To ensure accuracy in the researchers' interpretations of student and parent responses during interviews, member checking was employed. The findings

  13. A situated didactics of the philosophy a model to attend the estrangement of the teachers

    Directory of Open Access Journals (Sweden)

    Laura Susana Morales

    2013-01-01

    Full Text Available Training for Philosophy teachers, in the deductive curriculum frames, generates strangeness in those who carry on their internship and their first labor practices, when they come back to school. How to attend this estrangement from a specific didactics of the philosophy without denying the tension among technical, practical and experiential foregrounds? For this, a model denominated as Philosophy’s specific situated didactics is suggested. Such didactics has in its basis, besides the consideration that education is constituted by the tension of the above mentioned foregrounds, a conception of the philosophy referred to as philosophizing Philosophy, which takes into consideration both the subject of the philosophical activity and the disciplinary object, and is opposed to the academism from a perspective that nourishes itself in the situated thought as a philosophic category and in the experience understood as the transformation of subject. That’s why the mentioned didactical model breaks with the explanation, as the university teaching axis, and relies on the narration as the contact point for those involved in the training of trainers and those who begin in Philosophy teaching.

  14. Forensic engineering: Learning by accident. Teaching investigation skills to graduate students using real-life accident simulations

    NARCIS (Netherlands)

    Saunders-Smits, G.N.; Schuurman, M.J.; Rans, C.D.

    2015-01-01

    This paper relates the experiences of lecturers at Delft University of Technology in the designing and running of a Master course in Forensic Engineering. Rather than traditional face-to-face lectures, use of real-life evidence-based learning was made in the form of training for and execution of a m

  15. Sofosbuvir based treatment of chronic hepatitis C genotype 3 infections-A Scandinavian real-life study

    DEFF Research Database (Denmark)

    Dalgard, Olav; Weiland, Ola; Noraberg, Geir

    2017-01-01

    BACKGROUND AND AIMS: Chronic hepatitis C virus (HCV) genotype 3 infection with advanced liver disease has emerged as the most challenging to treat. We retrospectively assessed the treatment outcome of sofosbuvir (SOF) based regimes for treatment of HCV genotype 3 infections in a real life setting...

  16. LDL-C reductions and goal attainment among naive statin users in the Netherlands: real life results.

    NARCIS (Netherlands)

    Heintjes, E.M.; Hirsch, M.W.; Linden, MW van der; O'Donnell, J.C.; Stalenhoef, A.F.H.; Herings, R.M.C.

    2008-01-01

    OBJECTIVE: The effectiveness of statin therapy in a real life setting may differ from that in clinical trials, as physicians make non-randomised treatment decisions for patients with less uniform and possibly different characteristics. We therefore performed a study to compare the effectiveness of d

  17. Blue Tigers, Black Tapirs, & the Pied Raven of the Faroe Islands: Teaching Genetic Drift Using Real-Life Animal Examples

    Science.gov (United States)

    Robischon, Marcel

    2015-01-01

    Genetic drift is a concept of population genetics that is central to understanding evolutionary processes and aspects of conservation biology. It is frequently taught using rather abstract representations. I introduce three real-life zoological examples, based on historical and recent color morphs of tigers, tapirs, and ravens, that can complement…

  18. Using Real-Life Data When Teaching Statistics: Student Perceptions of this Strategy in an Introductory Statistics Course

    Science.gov (United States)

    Neumann, David L.; Hood, Michelle; Neumann, Michelle M.

    2013-01-01

    Many teachers of statistics recommend using real-life data during class lessons. However, there has been little systematic study of what effect this teaching method has on student engagement and learning. The present study examined this question in a first-year university statistics course. Students (n = 38) were interviewed and their reflections…

  19. Exploring Marine Ecosystems with Elementary School Portuguese Children: Inquiry-Based Project Activities Focused on "Real-Life" Contexts

    Science.gov (United States)

    Guilherme, Elsa; Faria, Cláudia; Boaventura, Diana

    2016-01-01

    The purpose of the study was to investigate how young students engage in an inquiry-based project driven by real-life contexts. Elementary school children were engaged in a small inquiry project centred on marine biodiversity and species adaptations. All activities included the exploration of an out-of-school setting as a learning context. A total…

  20. Social Cohesion as a Real-Life Phenomenon: Assessing the Explanatory Power of the Universalist and Particularist Perspectives

    Science.gov (United States)

    Janmaat, Jan Germen

    2011-01-01

    Unlike most studies on social cohesion, this study explores the concept as a real-life macro-level phenomenon. It assesses to what extent the conceptions of social cohesion suggested by several macro-level approaches represent coherent empirically observable forms of social cohesion. Additionally it discusses two perspectives on social…

  1. Using Real-Life Data When Teaching Statistics: Student Perceptions of this Strategy in an Introductory Statistics Course

    Science.gov (United States)

    Neumann, David L.; Hood, Michelle; Neumann, Michelle M.

    2013-01-01

    Many teachers of statistics recommend using real-life data during class lessons. However, there has been little systematic study of what effect this teaching method has on student engagement and learning. The present study examined this question in a first-year university statistics course. Students (n = 38) were interviewed and their reflections…

  2. Children's Toleration of Real-Life Aggression after Exposure to Media Violence: A Replication of the Drabman and Thomas Studies.

    Science.gov (United States)

    Molitor, Fred; Hirsch, Kenneth William

    1994-01-01

    Results of four mid-1970s experiments continue to be used as evidence that exposure to media violence desensitizes children to real-life aggression. This study replicated procedures from those experiments using contemporary video materials, and results confirmed original findings that children tend to tolerate more the aggressive behaviors of…

  3. Exploring Marine Ecosystems with Elementary School Portuguese Children: Inquiry-Based Project Activities Focused on "Real-Life" Contexts

    Science.gov (United States)

    Guilherme, Elsa; Faria, Cláudia; Boaventura, Diana

    2016-01-01

    The purpose of the study was to investigate how young students engage in an inquiry-based project driven by real-life contexts. Elementary school children were engaged in a small inquiry project centred on marine biodiversity and species adaptations. All activities included the exploration of an out-of-school setting as a learning context. A total…

  4. Real-life efficacy of pregabalin for the treatment of peripheral neuropathic pain in daily clinical practice in Denmark

    DEFF Research Database (Denmark)

    Crawford, Michael E; Poulsen, Peter Bo; Schiøttz-Christensen, Berit;

    2016-01-01

    OBJECTIVE: The aim of this study was to provide evidence regarding the real-life efficacy of pregabalin in the treatment of peripheral neuropathic pain (NeP) in Denmark. METHODS: In this prospective, observational, noninterventional study, pregabalin (Lyrica(®)) was prescribed following usual cli...

  5. The construction of visual-spatial situation models in children's reading and their relation to reading comprehension.

    Science.gov (United States)

    Barnes, Marcia A; Raghubar, Kimberly P; Faulkner, Heather; Denton, Carolyn A

    2014-03-01

    Readers construct mental models of situations described by text to comprehend what they read, updating these situation models based on explicitly described and inferred information about causal, temporal, and spatial relations. Fluent adult readers update their situation models while reading narrative text based in part on spatial location information that is consistent with the perspective of the protagonist. The current study investigated whether children update spatial situation models in a similar way, whether there are age-related changes in children's formation of spatial situation models during reading, and whether measures of the ability to construct and update spatial situation models are predictive of reading comprehension. Typically developing children from 9 to 16 years of age (N=81) were familiarized with a physical model of a marketplace. Then the model was covered, and children read stories that described the movement of a protagonist through the marketplace and were administered items requiring memory for both explicitly stated and inferred information about the character's movements. Accuracy of responses and response times were evaluated. Results indicated that (a) location and object information during reading appeared to be activated and updated not simply from explicit text-based information but from a mental model of the real-world situation described by the text; (b) this pattern showed no age-related differences; and (c) the ability to update the situation model of the text based on inferred information, but not explicitly stated information, was uniquely predictive of reading comprehension after accounting for word decoding. Copyright © 2013 Elsevier Inc. All rights reserved.

  6. Desensitization to portrayals of real-life aggression as a function of exposure to television violence.

    Science.gov (United States)

    Thomas, M H; Horton, R W; Lippincott, E C; Drabman, R S

    1977-06-01

    In two separate experiments, the hypothesis that exposure to violence in the context of television drama decreases subjects' emotional responsivity to portrayals of real-life aggression was tested. Subjects were shown either an excerpt from a violent police drama or a segment of an exciting but nonviolent volley-ball game before watching a videotaped scene of real aggression. Emotionality was measured by changes in skin resistance which was measured continuously throughout the session. In Experiment 1, subjects were 8- to 10-year-old children and the real aggression was a film of an argument and fight between two preschoolers. In Experiment 2, college students participated and reactions to real aggression were measured while subjects watched scenes from news films of the riots at the 1968 Democratic National Convention. With the exception of adult females, subjects who previously had viewed the aggression drama were less aroused by the scenes of real aggression than were subjects who had seen the control film. Further support for the hypothesis was provided by the finding that for most groups of subjects, the amount of television violence normally viewed was negatively related to responsivity while viewing aggression.

  7. Visualizing Dealumination of a Single Zeolite Domain in a Real-Life Catalytic Cracking Particle.

    Science.gov (United States)

    Kalirai, Sam; Paalanen, Pasi P; Wang, Jian; Meirer, Florian; Weckhuysen, Bert M

    2016-09-05

    Fluid catalytic cracking (FCC) catalysts play a central role in the chemical conversion of crude oil fractions. Using scanning transmission X-ray microscopy (STXM) we investigate the chemistry of one fresh and two industrially deactivated (ECAT) FCC catalysts at the single zeolite domain level. Spectro-microscopic data at the Fe L3 , La M5 , and Al K X-ray absorption edges reveal differing levels of deposited Fe on the ECAT catalysts corresponding with an overall loss in tetrahedral Al within the zeolite domains. Using La as a localization marker, we have developed a novel methodology to map the changing Al distribution of single zeolite domains within real-life FCC catalysts. It was found that significant changes in the zeolite domain size distributions as well as the loss of Al from the zeolite framework occur. Furthermore, inter- and intraparticle heterogeneities in the dealumination process were observed, revealing the complex interplay between metal-mediated pore accessibility loss and zeolite dealumination.

  8. A real life clinical practice of neurologists in the ambulatory setting in Thailand: a pragmatic study

    Directory of Open Access Journals (Sweden)

    Kannikar Kongbunkiat

    2015-06-01

    Full Text Available The burden of neurological disorders is high in developing countries. Real life data from neurologists as to how they practice in Thailand are limited in literature. Practices of neurologists in a university hospital clinical setting in Thailand were studied. A prospective study was performed at the ambulatory neurology clinic, Khon Kaen University Hospital, between 1 February and 31 October 2009. The following data were recorded: numbers of patients, characteristics of patients, consultation notes, and time spent for each patient. There were three neurologists, each of whom ran one afternoon clinic, once a week. There were 6137 visits during the 9 months, with an average of 681 visits per month. The total number of patients was 2834. The three most common diseases were cerebrovascular diseases (33%, epilepsy (16%, and movement disorders (non-Parkinson’s disease, 12%. Neurologists spent an average of 6.34 minutes per patient. In conclusion, neurologists in medical schools have limited time to take care of each patient. Several strategies are needed in medical education and neurology training to improve the quality of care.

  9. Application of Extended Fuzzy Programming Technique to a real life Transportation Problem in Neutrosophic environment

    Directory of Open Access Journals (Sweden)

    Dalbinder Kour

    2015-12-01

    Full Text Available This paper focuses on solving the transportation problems with neutrosophic data for the first time. The indeterminacy factor has been considered in Transportation Problems (TP. The two methods of linear programming – Fuzzy Linear Programming (FLP and Crisp Linear Programming (CLP are discussed with reference to neutrosophic transportation problems. The first method uses the membership, non-membership and indeterminacy degrees separately to find the crisp solution using the Fuzzy Programming Technique and then the optimal solution is calculated in terms of neutrosophic data with the help of defined cost membership functions. The satisfaction degree is then calculated to check the better solution. The second method directly solves the TP to find crisp solution considering a single objective function. The cost objective function is taken as neutrosophic data and the methods have been used as such for the first time. Both the methods have been illustrated with the help of a numerical example and these are then applied to solve a real life multi - objective and multi-index transportation problem. Finally the results are compared.

  10. Virtual Worlds: Relationship Between Real Life and Experience in Second Life

    Directory of Open Access Journals (Sweden)

    Scott P. Anstadt

    2013-09-01

    Full Text Available Due to the unique applications of virtual reality in many modern contexts, Second Life (SL offers inimitable opportunities for research and exploration and experiential learning as part of a distance learning curriculum assignment. A review of current research regarding SL examined real world social influences in online interactions and what the effects on users may be. This aids students in understanding the social constructionist perceptions and worldview of those persons they may serve in social services. This suggests the importance of developing an understanding of the relationship between users’ real life (RL and their SL. Some research has begun to reveal the effectiveness of telecommunication and computer simulation with certain clients in the fields of mental health and social work, yet there is a lack of sufficient research done within the context of virtual worlds. The current study surveyed users of several educationally and health focused SIMS (simulations as to what motivates their SL and RL interactions. The data explores associations between users’ RL and their SL in several areas,potentially addressing the future role of educating social work students regarding research methodology in online virtual reality interactions. Implications for social work are discussed including engaging clients using incentives for social participation built into the SL milieu.

  11. Exploring sustainability transitions in households: insights from real-life experiments

    Science.gov (United States)

    Baedeker, Carolin; Buhl, Johannes; Greiff, Kathrin; Hasselkuß, Marco; Liedtke, Christa; Lukas, Melanie

    2016-04-01

    Societal transformation towards sustainable consumption and production, especially in urban areas, is a key challenge. The design and implementation of sustainable product service systems (PSS) might be the initial point, in which private households play a major role. The Sustainable LivingLab research infrastructure was developed as an experimental setting for investigating consumption and production patterns in private households, especially to explore socio-technical innovations which are helpful to guide sustainability transitions. The suggested presentation describes results of several real-life experiments conducted in German households, e.g. the project SusLabNRW (North-Rhine Westphalia as part of the European SusLabNWE-Project), the EnerTransRuhr project as well as the PATHWAYS project that explore patterns of action, time use, social practices and the related resource use in private households. The presentation gives an overview of the employed methods and analysed data (qualitative interviews, social network analysis, survey on household activities and inventories and a sustainability assessment (resource profiles - MIPS household analysis). Households' resource consumption was calculated in all fields of activity to analyse social practices' impact. The presentation illustrates how aggregated data can inform scenario analysis and concludes with an outlook onto transition pathways at household level and socio-technical innovations in the fields of housing, nutrition and mobility.

  12. Real-life performance considerations of four pediatric multi-channel cochlear implant recipients.

    Science.gov (United States)

    Vidas, S; Hassan, R; Parnes, L S

    1992-12-01

    Most pediatric cochlear implant programs support a team approach for post-implant services. However, individuals directly involved in the care of these children often have differing opinions on the child's performance. We describe our experience with four children, aged 3 to 10 at the time of implantation, who have used the Nucleus 22-channel cochlear implant device for at least nine months. A questionnaire, focusing on the individual's observations of the child's speech and hearing performance in their particular setting (i.e., clinic, home, school), was completed by the child's parent(s), therapist and classroom teacher. Overall, performance in structured settings (i.e., testing and therapy sessions) was not in agreement with performance in unstructured settings (i.e., classroom and home environments). The results suggest that different individuals interacting with the same child in different environments often have differing perceptions of the child's performance. Based on the information obtained on the four cases, we discuss factors to consider in assessing the real-life performance of pediatric cochlear implant recipients.

  13. Moving through time: the role of personality in three real-life contexts.

    Science.gov (United States)

    Duffy, Sarah E; Feist, Michele I; McCarthy, Steven

    2014-01-01

    In English, two deictic space-time metaphors are in common usage: the Moving Ego metaphor conceptualizes the ego as moving forward through time and the Moving Time metaphor conceptualizes time as moving forward toward the ego (Clark, 1973). Although earlier research investigating the psychological reality of these metaphors has typically examined spatial influences on temporal reasoning (e.g., Boroditsky & Ramscar, 2002), recent lines of research have extended beyond this, providing initial evidence that personality differences and emotional experiences may also influence how people reason about events in time (Duffy & Feist, 2014; Hauser, Carter, & Meier, 2009; Richmond, Wilson, & Zinken, 2012). In this article, we investigate whether these relationships have force in real life. Building on the effects of individual differences in self-reported conscientiousness and procrastination found by Duffy and Feist (2014), we examined whether, in addition to self-reported conscientiousness and procrastination, there is a relationship between conscientious and procrastinating behaviors and temporal perspective. We found that participants who adopted the Moving Time perspective were more likely to exhibit conscientious behaviors, while those who adopted the Moving Ego perspective were more likely to procrastinate, suggesting that the earlier effects reach beyond the laboratory. Copyright © 2014 Cognitive Science Society, Inc.

  14. Acute hepatitis C in persons infected with the human immunodeficiency virus (HIV: The "Real-life Setting" proves the concept

    Directory of Open Access Journals (Sweden)

    Obermeier M

    2011-05-01

    HIV infected patients affects mainly MSM who acquire HCV sexually. Patients had a short duration of HIV infection and a stable immunological situation. In this real-life setting from urban regions in northern Germany, treatment rates appear to be high and effective.

  15. Mathematical model and algorithm of operation scheduling for monitoring situation in local waters

    Directory of Open Access Journals (Sweden)

    Sokolov Boris

    2017-01-01

    Full Text Available A multiple-model approach to description and investigation of control processes in regional maritime security system is presented. The processes considered in this paper were qualified as control processes of computing operations providing monitoring of the situation adding in the local water area and connected to relocation of different ships classes (further the active mobile objects (AMO. Previously developed concept of active moving object (AMO is used. The models describe operation of AMO automated monitoring and control system (AMCS elements as well as their interaction with objects-in-service that are sources or recipients of information being processed. The unified description of various control processes allows synthesizing simultaneously both technical and functional structures of AMO AMCS. The algorithm for solving the scheduling problem is described in terms of the classical theory of optimal automatic control.

  16. EDITORIAL Wireless sensor networks: design for real-life deployment and deployment experiences Wireless sensor networks: design for real-life deployment and deployment experiences

    Science.gov (United States)

    Gaura, Elena; Roedig, Utz; Brusey, James

    2010-12-01

    modalities and (iv) system solutions with high end-user added value and cost benefits. The common thread is deployment and deployment evaluation. In particular, satisfaction of application requirements, involvement of the end-user in the design and deployment process, satisfactory system performance and user acceptance are concerns addressed in many of the contributions. The contributions form a valuable set, which help to identify the priorities for research in this burgeoning area: Robust, reliable and efficient data collection in embedded wireless multi-hop networks are essential elements in creating a true deploy-and-forget user experience. Maintaining full connectivity within a WSN, in a real world environment populated by other WSNs, WiFi networks or Bluetooth devices that constitute sources of interference is a key element in any application, but more so for those that are safety-critical, such as disaster response. Awareness of the effects of wireless channel, physical position and line-of-sight on received signal strength in real-world, outdoor environments will shape the design of many outdoor applications. Thus, the quantification of such effects is valuable knowledge for designers. Sensors' failure detection, scalability and commercialization are common challenges in many long-term monitoring applications; transferable solutions are evidenced here in the context of pollutant detection and water quality. Innovative, alternative thinking is often needed to achieve the desired long-lived networks when power-hungry sensors are foreseen components; in some instances, the very problems of wireless technology, such as RF irregularity, can be transformed into advantages. The importance of an iterative design and evaluation methodology—from analysis to simulation to real-life deployment—should be well understood by all WSN developers. The value of this is highlighted in the context of a challenging WPAN video-surveillance application based on a novel Nomadic Access

  17. Adapting the SLIM diabetes prevention intervention to a Dutch real-life setting: joint decision making by science and practice.

    Science.gov (United States)

    Jansen, Sophia C; Haveman-Nies, Annemien; Duijzer, Geerke; Ter Beek, Josien; Hiddink, Gerrit J; Feskens, Edith J M

    2013-05-08

    Although many evidence-based diabetes prevention interventions exist, they are not easily applicable in real-life settings. Moreover, there is a lack of examples which describe the adaptation process of these interventions to practice. In this paper we present an example of such an adaptation. We adapted the SLIM (Study on Lifestyle intervention and Impaired glucose tolerance Maastricht) diabetes prevention intervention to a Dutch real-life setting, in a joint decision making process of intervention developers and local health care professionals. We used 3 adaptation steps in accordance with current adaptation frameworks. In the first step, the elements of the SLIM intervention were identified. In the second step, these elements were judged for their applicability in a real-life setting. In the third step, adaptations were proposed and discussed for those elements which were deemed not applicable. Participants invited for this process included intervention developers and local health care professionals (n=19). In the first adaptation step, a total of 22 intervention elements were identified. In the second step, 12 of these 22 intervention elements were judged as inapplicable. In the third step, a consensus was achieved for the adaptations of all 12 elements. The adapted elements were in the following categories: target population, techniques, intensity, delivery mode, materials, organisational structure, and political and financial conditions. The adaptations either lay in changing the SLIM protocol (6 elements) or the real-life working procedures (1 element), or a combination of both (4 elements). The positive result of this study is that a consensus was achieved within a relatively short time period (nine months) between the developers of the SLIM intervention and local health care professionals on the adaptations needed to make SLIM applicable in a Dutch real-life setting. Our example shows that it is possible to combine the perspectives of scientists and

  18. Age-sensitive effects of enduring work with alternating cognitive and physical load. A study applying mobile EEG in a real life working scenario

    Directory of Open Access Journals (Sweden)

    Edmund eWascher

    2016-01-01

    Full Text Available Ergonomic assessment of a workplace requires the evaluation of physical as well as cognitive aspects of a particular working situation. In particular the latter is hardly possible without interfering in the natural setting. Mobile acquisition of neurophysiological measures (such as parameters of the EEG may close this gap. At a simulated workplace we tracked older and younger participants with mobile EEG during a 4-5 hours work shift. They had to perform either a monotonous cognitive task, a self-paced cognitive task or a self-paced physical task in a predefined order. Self assessment, behavioral performance and spectral measures of the EEG (before most alpha power indicated that younger participants suffered from monotony. Older adults, on the other hand, were overall impaired by inefficient information processing. This was visible in EEG variations time-locked to eye blinks (blink-related synchronizations, a new measure to investigate cognitive processing in real life environments. Thus, we were able to distinguish between active and passive task-related aspects of mental fatigue without impinging on the natural working situation.

  19. Modeling Learner Situation Awareness in Collaborative Mobile Web 2.0 Learning

    Science.gov (United States)

    Norman, Helmi; Nordin, Norazah; Din, Rosseni; Ally, Mohamed

    2016-01-01

    The concept of situation awareness is essential in enhancing collaborative learning. Learners require information from different awareness aspects to deduce a learning situation for decision-making. Designing learning environments that assist learners to understand situation awareness via monitoring actions and reaction of other learners has been…

  20. On modified skew logistic regression model and its applications

    Directory of Open Access Journals (Sweden)

    C. Satheesh Kumar

    2015-12-01

    Full Text Available Here we consider a modified form of the logistic regression model useful for situations where the dependent variable is dichotomous in nature and the explanatory variables exhibit asymmetric and multimodal behaviour. The proposed model has been fitted to some real life data set by using method of maximum likelihood estimation and illustrated its usefulness in certain medical applications.

  1. Multiple Human Tracking in Complex Situation by Data Assimilation with Pedestrian Behavior Model

    Science.gov (United States)

    Nakanishi, W.; Fuse, T.

    2012-07-01

    A new method of multiple human tracking is proposed. The key concept is that to assume a tracking process as a data assimilation process. Despite the importance of understanding pedestrian behavior in public space with regard to achieving more sophisticated space design and flow control, automatic human tracking in complex situation is still challenging when people move close to each other or are occluded by others. For this difficulty, we stochastically combine existing tracking method by image processing with simulation models of walking behavior. We describe a system in a form of general state space model and define the components of the model according to the review on related works. Then we apply the proposed method to the data acquired at the ticket gate of the railway station. We show the high performance of the method, as well as compare the result with other model to present the advantage of integrating the behavior model to the tracking method. We also show the method's ability to acquire passenger flow information such as ticket gate choice and OD data automatically from the tracking result.

  2. Mathematical and Numerical Analysis of Model Equations on Interactions of the HIV/AIDS Virus and the Immune System

    Science.gov (United States)

    Parumasur, N.; Willie, R.

    2008-09-01

    We consider a simple HIV/AIDs finite dimensional mathematical model on interactions of the blood cells, the HIV/AIDs virus and the immune system for consistence of the equations to the real biomedical situation that they model. A better understanding to a cure solution to the illness modeled by the finite dimensional equations is given. This is accomplished through rigorous mathematical analysis and is reinforced by numerical analysis of models developed for real life cases.

  3. A Novel Reference Security Model with the Situation Based Access Policy for Accessing EPHR Data.

    Science.gov (United States)

    Gope, Prosanta; Amin, Ruhul

    2016-11-01

    Electronic Patient Health Record (EPHR) systems may facilitate a patient not only to share his/her health records securely with healthcare professional but also to control his/her health privacy, in a convenient and easy way even in case of emergency. In order to fulfill these requirements, it is greatly desirable to have the access control mechanism which can efficiently handle every circumstance without negotiating security. However, the existing access control mechanisms used in healthcare to regulate and restrict the disclosure of patient data are often bypassed in case of emergencies. In this article, we propose a way to securely share EPHR data under any situation including break-the-glass (BtG) without compromising its security. In this regard, we design a reference security model, which consists of a multi-level data flow hierarchy, and an efficient access control framework based on the conventional Role-Based Access Control (RBAC) and Mandatory Access Control (MAC) policies.

  4. Modelling microbiological water quality in the Seine river drainage network: past, present and future situations

    Science.gov (United States)

    Servais, P.; Billen, G.; Goncalves, A.; Garcia-Armisen, T.

    2007-09-01

    The Seine river watershed is characterized by a high population density and intense agricultural activities. Data show low microbiological water quality in the main rivers (Seine, Marne, Oise) of the watershed. Today, there is an increasing pressure from different social groups to restore microbiological water quality in order to both increase the safety of drinking water production and to restore the possible use of these rivers for bathing and rowing activities, as they were in the past. A model, appended to the hydro-ecological SENEQUE/Riverstrahler model describing the functioning of large river systems, was developed to describe the dynamics of faecal coliforms (FC), the most usual faecal contamination indicator. The model is able to calculate the distribution of FC concentrations in the whole drainage network resulting from land use and wastewater management in the watershed. The model was validated by comparing calculated FC concentrations with available field data for some well-documented situations in different river stretches of the Seine drainage network. Once validated, the model was used to test various predictive scenarios, as, for example, the impact of the modifications in wastewater treatment planned at the 2012 horizon in the Seine watershed in the scope of the implementation of the european water framework directive. The model was also used to investigate past situations. In particular, the variations of the microbiological water quality in the Parisian area due to population increase and modifications in wastewater management were estimated over the last century. It was shown that the present standards for bathing and other aquatic recreational activities are not met in the large tributaries upstream from Paris since the middle of the 1950's, and at least since the middle of the XIXth century in the main branch of the Seine river downstream from Paris. Efforts carried out for improving urban wastewater treatment in terms or organic matter and

  5. Modelling microbiological water quality in the Seine river drainage network: past, present and future situations

    Directory of Open Access Journals (Sweden)

    P. Servais

    2007-05-01

    Full Text Available The Seine river watershed is characterized by a high population density and intense agricultural activities. Data show low microbiological water quality in the main rivers (Seine, Marne, Oise of the watershed. Today, there is an increasing pressure from different social groups to restore microbiological water quality in order to both increase the safety of drinking water production and to restore the possible use of these rivers for bathing and rowing activities, as they were in the past. A model, appended to the hydro-ecological SENEQUE/Riverstrahler model describing the functioning of large river systems, was developed to describe the dynamics of faecal coliforms (FC, the most usual faecal contamination indicator. The model is able to calculate the distribution of FC abundance in the whole drainage network resulting from land use and wastewater management in the watershed. The model was validated by comparing calculated FC concentrations with available field data for some well-documented situations in different river stretches of the Seine drainage network. Once validated, the model was used to test various predictive scenarios, as, for example, the impact of the modifications in wastewater treatment planned at the 2012 horizon in the Seine watershed in the scope of the implementation of the European Water Framework Directive. The model was also used to investigate past situations. In particular, the variations of the microbiological water quality in the Parisian area due to population increase and modifications in wastewater management were estimated over the last century. It was shown that the present standards for bathing and other aquatic recreational activities are not met in the large tributaries upstream from Paris since the middle of the 1950's, and at least since the middle of the XIXth century in the main branch of the Seine river downstream from Paris. Efforts carried out for improving urban wastewater treatment in terms or

  6. Modelling microbiological water quality in the Seine river drainage network: past, present and future situations

    Directory of Open Access Journals (Sweden)

    P. Servais

    2007-09-01

    Full Text Available The Seine river watershed is characterized by a high population density and intense agricultural activities. Data show low microbiological water quality in the main rivers (Seine, Marne, Oise of the watershed. Today, there is an increasing pressure from different social groups to restore microbiological water quality in order to both increase the safety of drinking water production and to restore the possible use of these rivers for bathing and rowing activities, as they were in the past. A model, appended to the hydro-ecological SENEQUE/Riverstrahler model describing the functioning of large river systems, was developed to describe the dynamics of faecal coliforms (FC, the most usual faecal contamination indicator. The model is able to calculate the distribution of FC concentrations in the whole drainage network resulting from land use and wastewater management in the watershed. The model was validated by comparing calculated FC concentrations with available field data for some well-documented situations in different river stretches of the Seine drainage network. Once validated, the model was used to test various predictive scenarios, as, for example, the impact of the modifications in wastewater treatment planned at the 2012 horizon in the Seine watershed in the scope of the implementation of the european water framework directive. The model was also used to investigate past situations. In particular, the variations of the microbiological water quality in the Parisian area due to population increase and modifications in wastewater management were estimated over the last century. It was shown that the present standards for bathing and other aquatic recreational activities are not met in the large tributaries upstream from Paris since the middle of the 1950's, and at least since the middle of the XIXth century in the main branch of the Seine river downstream from Paris. Efforts carried out for improving urban wastewater treatment in terms

  7. Analogs in the treatment of chronic hepatitis B: real life experience with tenofovir and entecavir

    Directory of Open Access Journals (Sweden)

    Rosanna Villani

    2015-06-01

    Full Text Available INTRODUCTION: Tenofovir and entecavir are potent antiviral agents. By suppressing viral replication, they induce histological improvement and finally delay the progression of chronic hepatitis B and the development of complications. They are rarely associated with serious side effects. Our data from a real life experience support data from the literature and suggest some minimal difference that may be useful in tailoring therapy.PATIENTS AND METHODS: We retrospectively analyzed 54 patients affected by chronic hepatitis B (31 and 23 treated by entecavir and tenofovir, respectively. Eight patients were cirrhotic. At baseline and 4-12 and 24 weeks after starting therapy, biochemical and virological analysis were performed in all patients. Renal function tests (serum creatinine, creatinine clearance and blood urea, serum (calcium and phosphate blood level and urine electrolyte were also studied.RESULTS: All the patients reached virological control within 24 weeks. Only in the group treated by tenofovir we observed a complete viral suppression within 12 weeks. Some patients treated with tenofovir showed increased creatinine clearance without serum creatinine alteration. No significant side effects were reported with the exception of one case of persistent headache in the entecavir group for which the drug was suspended.CONCLUSIONS: Entecavir and tenofovir are effective in suppressing viral replication in patients with chronic hepatitis B. Tenofovir is more potent than entecavir and viral replication is blocked within 12 weeks of therapy. Tenofovir administration is associated with slight increase of creatinine clearance without alteration of serum creatinine levels. The choice of one or the other should be made according to target and specific patients characteristics. In patients with high serum viral load where the complete and quick control of viral replication is the main target, tenofovir may represent the best choice.

  8. Clinical relevance of cluster analysis in phenotyping allergic rhinitis in a real-life study.

    Science.gov (United States)

    Bousquet, Philippe Jean; Devillier, Philippe; Tadmouri, Abir; Mesbah, Kamal; Demoly, Pascal; Bousquet, Jean

    2015-01-01

    Disease stratification, using phenotypic characterization performed either by hypothesis- or data-driven methods, was developed to improve clinical decisions. However, cluster analysis has not been used for allergic rhinitis. To define clusters in allergic rhinitis and to compare them with ARIA (Allergic Rhinitis and Its Impact on Asthma), a hypothesis-driven approach. A French observational prospective multicenter study (EVEIL: Echelle visuelle analogique dans la rhinite allergique) was carried out on 990 patients consulting general practitioners for allergic rhinitis and treated as per clinical practice. In this study, changes in symptom scores, visual analogue scales and quality of life were measured at baseline and after 14 days of treatment. A post hoc analysis was performed to identify clusters of patients with allergic rhinitis – using Ward's hierarchical method – and to define their clinical relevance at baseline and after 14 days of treatment. The cluster approach was compared to the ARIA approach. Patients were clustered into 4 phenotypes which partly followed the ARIA classes. These phenotypes differed in their disease severity including symptoms and quality of life. Physicians in real-life practice prescribed medication regardless of the phenotype and severity, with the exception of patients with ocular symptoms. Prescribed treatments were comparable in hypothesis- and data-driven analyses. The prevalence of uncontrolled patients during treatment was similar in the 4 clusters, but was significantly different according to the ARIA classes. Cluster analysis using demographic and clinical parameters only does not appear to add relevant information for disease stratification in allergic rhinitis. © 2015 S. Karger AG, Basel.

  9. Patients with asthma and comorbid allergic rhinitis: is optimal quality of life achievable in real life?

    Directory of Open Access Journals (Sweden)

    Fulvio Braido

    Full Text Available OBJECTIVES: Asthma trials suggest that patients reaching total disease control have an optimal Health Related Quality of Life (HRQoL. Moreover, rhinitis is present in almost 80% of asthmatics and impacts asthma control and patient HRQoL. We explored whether optimal HRQoL was reachable in a real-life setting, and evaluated the disease and patient related patterns associated to optimal HRQoL achievement. METHODS AND FINDINGS: Asthma and rhinitis HRQoL, illness perception, mood profiles, rhinitis symptoms and asthma control were assessed by means of validated tools in patients classified according to GINA and ARIA guidelines. Optimal HRQoL, identified by a Rhinasthma Global Summary (GS score ≤20 (score ranging from 0 to 100, where 100 represents the worst possible HRQoL, was reached by 78/209 (37.32%. With the exception of age, no associations were found between clinical and demographic characteristics and optimal HRQoL achievement. Patients reaching an optimal HRQoL differed in disease perception and mood compared to those not reaching an optimal HRQoL. Asthma control was significantly associated with optimal HRQoL (χ(2 = 49.599; p<0.001 and well-controlled and totally controlled patients significantly differed in achieving optimal HRQoL (χ(2 = 7.617; p<0.006. CONCLUSION: Approximately one third of the patients in our survey were found to have an optimal HRQoL. While unsatisfactory disease control was the primary reason why the remainder failed to attain optimal HRQoL, it is clear that illness perception and mood also played parts. Therefore, therapeutic plans should be directed not only toward achieving the best possible clinical control of asthma and comorbid rhinitis, but also to incorporating individualized elements according to patient-related characteristics.

  10. Local contextual processing of abstract and meaningful real-life images in professional athletes.

    Science.gov (United States)

    Fogelson, Noa; Fernandez-Del-Olmo, Miguel; Acero, Rafael Martín

    2012-05-01

    We investigated the effect of abstract versus real-life meaningful images from sports on local contextual processing in two groups of professional athletes. Local context was defined as the occurrence of a short predictive series of stimuli occurring before delivery of a target event. EEG was recorded in 10 professional basketball players and 9 professional athletes of individual sports during three sessions. In each session, a different set of visual stimuli were presented: triangles facing left, up, right, or down; four images of a basketball player throwing a ball; four images of a baseball player pitching a baseball. Stimuli consisted of 15 % targets and 85 % of equal numbers of three types of standards. Recording blocks consisted of targets preceded by randomized sequences of standards and by sequences including a predictive sequence signaling the occurrence of a subsequent target event. Subjects pressed a button in response to targets. In all three sessions, reaction times and peak P3b latencies were shorter for predicted targets compared with random targets, the last most informative stimulus of the predictive sequence induced a robust P3b, and N2 amplitude was larger for random targets compared with predicted targets. P3b and N2 peak amplitudes were larger in the professional basketball group in comparison with professional athletes of individual sports, across the three sessions. The findings of this study suggest that local contextual information is processed similarly for abstract and for meaningful images and that professional basketball players seem to allocate more attentional resources in the processing of these visual stimuli.

  11. AN ADVISER IN RESOURCE-MANAGEMENT SITUATIONS - CONFIGURAL WEIGHING OF RECOMMENDATIONS

    NARCIS (Netherlands)

    DEVRIES, S; WILKE, HAM

    1995-01-01

    The major aim of the present study is to investigate how an adviser's recommendations affect the behavior of actors in resource management situations. Some real-life examples of resource management situations are: fishing the seas and water consumption in a period of draught. In previous research (s

  12. Long-term Course of Alzheimer Disease in Patients Treated According to the Dutch Dementia Guideline at a Memory Clinic A "Real-Life" Study

    NARCIS (Netherlands)

    Droogsma, Erika; van Asselt, Dieneke; van Steijn, Jolanda; Diekhuis, Marjolein; Veeger, Nic; De Deyn, Peter P.

    2016-01-01

    Introduction:There is little knowledge of the long-term course of Alzheimer disease (AD) in light of current pharmacological and nonpharmacological interventions provided in a real-life setting.Methods:The Frisian Alzheimer's Disease Cohort study is a real-life study of the course of AD in patients

  13. Long-term Course of Alzheimer Disease in Patients Treated According to the Dutch Dementia Guideline at a Memory Clinic A "Real-Life" Study

    NARCIS (Netherlands)

    Droogsma, Erika; van Asselt, Dieneke; van Steijn, Jolanda; Diekhuis, Marjolein; Veeger, Nic; De Deyn, Peter P.

    2016-01-01

    Introduction:There is little knowledge of the long-term course of Alzheimer disease (AD) in light of current pharmacological and nonpharmacological interventions provided in a real-life setting.Methods:The Frisian Alzheimer's Disease Cohort study is a real-life study of the course of AD in patients

  14. SMART-ER: a Situation Model of Anticipated Response consequences in Tactical decisions in skill acquisition - Extended and Revised.

    Science.gov (United States)

    Raab, Markus

    2014-01-01

    Situation Model of Anticipated Response consequences in tactical decisions (SMART) describes the interaction of top-down and bottom-up processes in skill acquisition and thus the dynamic interaction of sensory and motor capacities in embodied cognition. The empirically validated, extended, and revised SMART-ER can now predict when specific dynamic interactions of top-down and bottom-up processes have a beneficial or detrimental effect on performance and learning depending on situational constraints. The model is empirically supported and proposes learning strategies for when situation complexity varies or time pressure is present. Experiments from expertise research in sports illustrate that neither bottom-up nor top-down processes are bad or good per se but their effects depend on personal and situational characteristics.

  15. The Nordic Model in a Global Company Situated in Norway. Challenging Institutional Orders?

    Directory of Open Access Journals (Sweden)

    Elin Kvande

    2012-11-01

    Full Text Available In this article, we explore the impact of internationalization as organizational processes where institutional actors meet in local contexts and negotiate the institutional order. The internationalization of working life implies that different traditions and practices meet and challenge each other. The focus is on how important elements of the Nordic micro model like cooperation between employees and employers and regulation of working hours are implemented in a global company situated in Norway. In general, it seems that employees and employers cooperate in line with this tradition in the Nordic micro model. Norwegian manager’s practices are described to be in accordance with Scandinavian management traditions, while managers from the United States appear to practice management consistent with the liberal working life model. The findings show a tension-filled clash between two different management practices, which indicates that the Nordic micro model in this field might be under pressure. Manager’s recommendation to the employees was not to become members of the trade union. The absence of trade unions in the organization implies that employees and employers are not cooperating on a collective level. This means that only parts of the regulatory arrangement related to participation and cooperation are implemented. Findings concerning working time and the relation to the institutional order represented by the Norwegian Work Environment Act indicate a clear tension between different institutional traditions in the organization. The company does not respect the Norwegian in working time regulations. These regulations are seen as counterproductive for a company that competes in the international market. This devaluation of the regulations in the Nordic model implies that the institutional order represented in the Nordic micro model is challenged.

  16. Absent yet Present: On the Paradoxical Nature of Characters in Nabokov’s The Real Life of Sebastian Knight

    Directory of Open Access Journals (Sweden)

    Irina Marchesini

    2016-11-01

    Full Text Available The present research is focused on the theme of absence, an area of inquiry that might seem dominant in the field of Nabokov Studies. The analysis, which concentrates in particular on the key figures of the novel The Real Life of Sebastian Knight (1941, notably the narrator V. and the poet Sebastian Knight, interprets the characters’ construction through the paradigm of absence. Arguably, the construction of characters in The Real Life of Sebastian Knight is paradoxical: absence constitutes their essence at a core level, as it often happens in the context of the self-conscious genre. Moreover, absence plays a key role in characters’ design, linking them to all Nabokovian novels. However, despite their innermost ‘flatness’, to use Edward M. Forster’s terminology, they still appear to be ‘round’, i.e. plausible, mimetic figures.

  17. An Instructional Model for Guiding Reflection and Research in the Classroom: The Educational Situation Quality Model

    Science.gov (United States)

    Domenech-Betoret, Fernando

    2013-01-01

    The purpose of this work is to present an instructional model entitled the "Modelo de Calidad de Situacion Educativa" (MCSE) and how teachers can use it to reflect and investigate in a formal educational setting. It is a theoretical framework which treat to explain the functioning of an educational setting by organizing and relating the…

  18. An Instructional Model for Guiding Reflection and Research in the Classroom: The Educational Situation Quality Model

    Science.gov (United States)

    Domenech-Betoret, Fernando

    2013-01-01

    The purpose of this work is to present an instructional model entitled the "Modelo de Calidad de Situacion Educativa" (MCSE) and how teachers can use it to reflect and investigate in a formal educational setting. It is a theoretical framework which treat to explain the functioning of an educational setting by organizing and relating the…

  19. Modifying social anxiety related to a real-life stressor using online Cognitive Bias Modification for interpretation ☆

    OpenAIRE

    Hoppitt, Laura; Illingworth, Josephine L.; MacLeod, Colin; Hampshire, Adam; Dunn, Barnaby D.; Mackintosh, Bundy

    2014-01-01

    Modifying threat related biases in attention and interpretation has been shown to successfully reduce global symptoms of anxiety in high anxious and clinically anxious samples (termed Cognitive Bias Modification, CBM). However, the possibility that CBM can be used as a way to prevent anxiety associated with an upcoming real-life stressful event in vulnerable populations has yet to be systematically examined. The present study aimed to assess whether a two-week course of online CBM for interpr...

  20. Measurement of Walking Ground Reactions in Real-Life Environments: A Systematic Review of Techniques and Technologies.

    Science.gov (United States)

    Shahabpoor, Erfan; Pavic, Aleksandar

    2017-09-12

    Monitoring natural human gait in real-life environments is essential in many applications, including quantification of disease progression, monitoring the effects of treatment, and monitoring alteration of performance biomarkers in professional sports. Nevertheless, developing reliable and practical techniques and technologies necessary for continuous real-life monitoring of gait is still an open challenge. A systematic review of English-language articles from scientific databases including Scopus, ScienceDirect, Pubmed, IEEE Xplore, EBSCO and MEDLINE were carried out to analyse the 'accuracy' and 'practicality' of the current techniques and technologies for quantitative measurement of the tri-axial walking ground reactions outside the laboratory environment, and to highlight their strengths and shortcomings. In total, 679 relevant abstracts were identified, 54 full-text papers were included in the paper and the quantitative results of 17 papers were used for meta-analysis and comparison. Three classes of methods were reviewed: (1) methods based on measured kinematic data; (2) methods based on measured plantar pressure; and (3) methods based on direct measurement of ground reactions. It was found that all three classes of methods have competitive accuracy levels with methods based on direct measurement of the ground reactions showing highest accuracy while being least practical for long-term real-life measurement. On the other hand, methods that estimate ground reactions using measured body kinematics show highest practicality of the three classes of methods reviewed. Among the most prominent technical and technological challenges are: (1) reducing the size and price of tri-axial load-cells; (2) improving the accuracy of orientation measurement using IMUs; (3) minimizing the number and optimizing the location of required IMUs for kinematic measurement; (4) increasing the durability of pressure insole sensors, and (5) enhancing the robustness and versatility of the

  1. Measurement of Walking Ground Reactions in Real-Life Environments: A Systematic Review of Techniques and Technologies

    Directory of Open Access Journals (Sweden)

    Erfan Shahabpoor

    2017-09-01

    Full Text Available Monitoring natural human gait in real-life environments is essential in many applications, including quantification of disease progression, monitoring the effects of treatment, and monitoring alteration of performance biomarkers in professional sports. Nevertheless, developing reliable and practical techniques and technologies necessary for continuous real-life monitoring of gait is still an open challenge. A systematic review of English-language articles from scientific databases including Scopus, ScienceDirect, Pubmed, IEEE Xplore, EBSCO and MEDLINE were carried out to analyse the ‘accuracy’ and ‘practicality’ of the current techniques and technologies for quantitative measurement of the tri-axial walking ground reactions outside the laboratory environment, and to highlight their strengths and shortcomings. In total, 679 relevant abstracts were identified, 54 full-text papers were included in the paper and the quantitative results of 17 papers were used for meta-analysis and comparison. Three classes of methods were reviewed: (1 methods based on measured kinematic data; (2 methods based on measured plantar pressure; and (3 methods based on direct measurement of ground reactions. It was found that all three classes of methods have competitive accuracy levels with methods based on direct measurement of the ground reactions showing highest accuracy while being least practical for long-term real-life measurement. On the other hand, methods that estimate ground reactions using measured body kinematics show highest practicality of the three classes of methods reviewed. Among the most prominent technical and technological challenges are: (1 reducing the size and price of tri-axial load-cells; (2 improving the accuracy of orientation measurement using IMUs; (3 minimizing the number and optimizing the location of required IMUs for kinematic measurement; (4 increasing the durability of pressure insole sensors, and (5 enhancing the robustness and

  2. How to Model a Likely Behavior of a Pedagogical Agent from a Real Situation

    Directory of Open Access Journals (Sweden)

    Mohamedade Farouk NANNE

    2015-09-01

    Full Text Available The aim of this work is to model the behavior verbal and nonverbal behavior of a Pedagogical Agent (PA can be integrated into an Intelligent Tutoring System. The following research questions were posed: what is the nonverbal component of an educational communication? How to study this component for a computational model of plausible behavior of a virtual agent? What correlations between educational actions and the direction of gaze of a human agent? To carry out exploratory work, a methodological approach based on multi-modal video corpus study was adopted. Within a multidisciplinary team consisting of computer scientists and didactics of mathematics, an educational situation in which a virtual pedagogical agent is likely was developed. Dyadic interactions between teachers and learners late second early third (15-16 years in a skills assessment interview in mathematics following the resolution of exercises by students with a mathematics software was filmed. A multi-level annotation scheme to annotate the observed behavior was proposed. The multidisciplinary research subject (ITS, Human-Machine Interfaces, Educational sciences, educational, linguistic etc. due to the development of the coding scheme a delicate but important work given the wealth of knowledge from different disciplines. After a portion of the collected work annotation corpus statistical measures derived from annotations carried out suggest different strategies for teachers in terms of gaze direction depending on the learner profile and pedagogical actions. These measures have enabled to extract rules to control the nonverbal behavior of a PA.

  3. Evolving Model for the Complex Traffic and Transportation Network Considering Self-Growth Situation

    Directory of Open Access Journals (Sweden)

    Wei Zhang

    2012-01-01

    Full Text Available It has been approved that the scale-free feature exists in various complex networks, such as the internet, the cell or the biological networks. In order to analyze the influence of the self-growth phenomenon during the growth on the structure of traffic and transportation network, we formulated an evolving model. Based on the evolving model, we prove in mathematics that, even that the self-growth situation happened, the traffic and transportation network owns the scale-free feature due to that the node degree follows a power-law distribution. A real traffic and transportation network, China domestic airline network is tested to consolidate our conclusions. We find that the airline network has a node degree distribution equivalent to the power-law of which the estimated scaling parameter is about 3.0. Moreover the standard error of the estimated scaling parameter changes according to the self-growth probability. Our findings could provide useful information for determining the optimal structure or status of the traffic and transportation network.

  4. Schizophrenia in real life: courses, symptoms and functioning in an Italian population

    Directory of Open Access Journals (Sweden)

    Turola Maria

    2012-10-01

    Full Text Available Abstract Background In the general belief, schizophrenia is associated with the concepts of seriousness, incurability, dangerousness: this is incorrect. In recent decades, the interest in course studies increased and different trends emerged, not necessarily chronic, with the possibility of remission. The plan of this research was to draw a picture of the schizophrenia syndrome in a specific geographic area, in the past and at present time: this allows to detect needs, weaknesses and strengths, for a better planning of future interventions. Methods The course of all cases diagnosed as schizophrenia (N = 1,759 in the period 1978–2008, was retrospectively studied in the entire population of an Italian province by observing, for a mean period of 12 years per person, age at first psychiatric consultation, number and length of admissions for both acute symptoms and residential-rehabilitation programs, number of interventions in outpatients. The cases under treatment (N = 842, were evaluated in terms of symptoms, using the Brief Psychiatric Rating Scale, and in terms of functioning, using the Personal and Social Functioning Scale. Results The disease course differs significantly between genders: males have an earlier age at first consultation (about 7 years earlier, higher admission rates, greater number of outpatient interventions and personal and social functioning significantly worse. Hospitalization resulted often unnecessary: 23.1% of cases were never hospitalized and 67.2% spent less than one week per year in hospital. A quarter of the cases meets the international criteria for remission and more than 75% are asymptomatic or mildly symptomatic; only 5.3% of cases shows severe symptoms. However, Personal and Social Functioning highlights, in about 1/3 of cases, relevant or serious problems mainly in Work and Relationships areas, whilst Aggressiveness is a serious problem only in 9%. Conclusions In this population, schizophrenia in real

  5. Understanding of a Key Aspect of Situation Awareness: A Research and Development Agenda to Refine the Model of Spatial Orientation

    Science.gov (United States)

    2017-07-10

    USAARL Report No. 2017-14 Understanding of a Key Aspect of Situation Awareness: A Research and Development Agenda to Refine the Model of Spatial...Understanding of a Key Aspect of Situation Awareness: a Research and Development Agenda to Refine the Model of Spatial Orientation N/A N/A N/A N/A N/A N/A Lawson...supporting the initial model development for military applications by authors Newman, Lawson, and Rupert.  Small Business Innovative Research program

  6. Nonlinear Heart Rate Variability features for real-life stress detection. Case study: students under stress due to university examination.

    Science.gov (United States)

    Melillo, Paolo; Bracale, Marcello; Pecchia, Leandro

    2011-11-07

    This study investigates the variations of Heart Rate Variability (HRV) due to a real-life stressor and proposes a classifier based on nonlinear features of HRV for automatic stress detection. 42 students volunteered to participate to the study about HRV and stress. For each student, two recordings were performed: one during an on-going university examination, assumed as a real-life stressor, and one after holidays. Nonlinear analysis of HRV was performed by using Poincaré Plot, Approximate Entropy, Correlation dimension, Detrended Fluctuation Analysis, Recurrence Plot. For statistical comparison, we adopted the Wilcoxon Signed Rank test and for development of a classifier we adopted the Linear Discriminant Analysis (LDA). Almost all HRV features measuring heart rate complexity were significantly decreased in the stress session. LDA generated a simple classifier based on the two Poincaré Plot parameters and Approximate Entropy, which enables stress detection with a total classification accuracy, a sensitivity and a specificity rate of 90%, 86%, and 95% respectively. The results of the current study suggest that nonlinear HRV analysis using short term ECG recording could be effective in automatically detecting real-life stress condition, such as a university examination.

  7. Real-life memory and spatial navigation in patients with focal epilepsy: ecological validity of a virtual reality supermarket task.

    Science.gov (United States)

    Grewe, P; Lahr, D; Kohsik, A; Dyck, E; Markowitsch, H J; Bien, C G; Botsch, M; Piefke, M

    2014-02-01

    Ecological assessment and training of real-life cognitive functions such as visual-spatial abilities in patients with epilepsy remain challenging. Some studies have applied virtual reality (VR) paradigms, but external validity of VR programs has not sufficiently been proven. Patients with focal epilepsy (EG, n=14) accomplished an 8-day program in a VR supermarket, which consisted of learning and buying items on a shopping list. Performance of the EG was compared with that of healthy controls (HCG, n=19). A comprehensive neuropsychological examination was administered. Real-life performance was investigated in a real supermarket. Learning in the VR supermarket was significantly impaired in the EG on different VR measures. Delayed free recall of products did not differ between the EG and the HCG. Virtual reality scores were correlated with neuropsychological measures of visual-spatial cognition, subjective estimates of memory, and performance in the real supermarket. The data indicate that our VR approach allows for the assessment of real-life visual-spatial memory and cognition in patients with focal epilepsy. The multimodal, active, and complex VR paradigm may particularly enhance visual-spatial cognitive resources.

  8. Nonlinear Heart Rate Variability features for real-life stress detection. Case study: students under stress due to university examination

    Directory of Open Access Journals (Sweden)

    Melillo Paolo

    2011-11-01

    Full Text Available Abstract Background This study investigates the variations of Heart Rate Variability (HRV due to a real-life stressor and proposes a classifier based on nonlinear features of HRV for automatic stress detection. Methods 42 students volunteered to participate to the study about HRV and stress. For each student, two recordings were performed: one during an on-going university examination, assumed as a real-life stressor, and one after holidays. Nonlinear analysis of HRV was performed by using Poincaré Plot, Approximate Entropy, Correlation dimension, Detrended Fluctuation Analysis, Recurrence Plot. For statistical comparison, we adopted the Wilcoxon Signed Rank test and for development of a classifier we adopted the Linear Discriminant Analysis (LDA. Results Almost all HRV features measuring heart rate complexity were significantly decreased in the stress session. LDA generated a simple classifier based on the two Poincaré Plot parameters and Approximate Entropy, which enables stress detection with a total classification accuracy, a sensitivity and a specificity rate of 90%, 86%, and 95% respectively. Conclusions The results of the current study suggest that nonlinear HRV analysis using short term ECG recording could be effective in automatically detecting real-life stress condition, such as a university examination.

  9. Application of Data Warehouse in Real Life: State-of-the-art Survey from User Preferences’ Perspective

    Directory of Open Access Journals (Sweden)

    Muhammad Bilal Shahid

    2016-04-01

    Full Text Available In recent years, due to increase in data complexity and manageability issues, data warehousing has attracted a great deal of interest in real life applications especially in business, finance, healthcare and industries. As the importance of retrieving the information from knowledge-base cannot be denied, data warehousing is all about making the information available for decision making. Data warehouse is accepted as the heart of the latest decision support systems. Due to the eagerness of data warehouse in real life, the need for the design and implementation of data warehouse in different applications is becoming crucial. Information from operational data sources are integrated by data warehousing into a central repository to start the process of analysis and mining of integrated information and primarily used in strategic decision making by means of online analytical processing techniques (OLAP. Despite the applications of data warehousing techniques in number of areas, there is no comprehensive literature review for it. This survey paper is an effort to present the applications of data warehouse in real life. It focuses to help the scholars knowing the analysis of data warehouse applications in number of domains. This survey provides applications, case studies and analysis of data warehouse used in various domains based on user preferences.

  10. Profinteg: A Tool for Real-Life Assessment of Activities of Daily Living in Patients with Cognitive Impairment

    Directory of Open Access Journals (Sweden)

    Patrick Anselme

    2013-03-01

    Full Text Available Although there are many instruments for assessing activities of daily living (IADL in brain injured patients, few instruments specifically target cognitive impairment and its impact on IADL. The present study presents the development of the Profinteg instrument, a tool for real-life assessment as well as rehabilitation of IADL in patients with cognitive impairment. This two-stage instrument covers over 90 activities. Psychometric properties of the different Profinteg measures were explored in twenty-five patients with mild to severe cognitive difficulties and twenty-five caregivers. The feasibility of the Profinteg rehabilitation procedure was explored in three patients. Excellent interrater reliability ('r' > 0.90,' ''p' < 0.01 was observed for all measures. Good sensitivity to changes in IADL disability over time was also observed ('T' = 2.37, 'p' < 0.02. Significant improvement of IADL functioning was found after rehabilitation guided by Profinteg assessment. The Profinteg instrument detects with precision the difficulties patients encounter in their real-life setting via (1 assessment of a large number of activities and (2 detailed decomposition of activities into sub-activities. The Profinteg tool also provides promising results for guidance of IADL rehabilitation in the patient's real-life environment.

  11. Drop-out rate among patients treated with omalizumab for severe asthma: Literature review and real-life experience.

    Science.gov (United States)

    Caminati, M; Senna, G; Stefanizzi, G; Bellamoli, R; Longhi, S; Chieco-Bianchi, F; Guarnieri, G; Tognella, S; Olivieri, M; Micheletto, C; Festi, G; Bertocco, E; Mazza, M; Rossi, A; Vianello, A

    2016-08-25

    In patients with asthma, particularly severe asthma, poor adherence to inhaled drugs negatively affects the achievement of disease control. A better adherence rate is expected in the case of injected drugs, such as omalizumab, as they are administered only in a hospital setting. However, adherence to omalizumab has never been systematically investigated. The aim of this study was to review the omalizumab drop-out rate in randomized controlled trials (RCTs) and real-life studies. A comparative analysis was performed between published data and the Italian North East Omalizumab Network (NEONet) database. In RCTs the drop-out rate ranged from 7.1 to 19.4 %. Although the reasons for withdrawal were only occasionally reported, patient decision and adverse events were the most frequently reported causes. In real-life studies the drop-out rate ranged from 0 to 45.5 %. In most cases lack of efficacy was responsible for treatment discontinuation. According to NEONet data, 32 % of treated patients dropped out, with an increasing number of drop outs observed over time. Patient decision and lack of efficacy accounted for most treatment withdrawals. Treatment adherence is particularly crucial in patients with severe asthma considering the clinical impact of the disease and the cost of non-adherence. The risk of treatment discontinuation has to be carefully considered both in the experimental and real-life settings. Increased knowledge regarding the main reasons for patient withdrawal is important to improve adherence in clinical practice.

  12. Self-disclosure through weblogs and perceptions of online and "real-life" friendships among female bloggers.

    Science.gov (United States)

    Bane, Cynthia M H; Cornish, Marilyn; Erspamer, Nicole; Kampman, Lia

    2010-04-01

    The current study examined female bloggers' perceptions of online and "real-life" same-sex friendships and examined relationships between self-disclosure through blogs and perceptions of the two types of friendships. Three hundred seven female bloggers (M age = 34.56 years) completed an online survey regarding friendship satisfaction and perceptions of intimacy-promoting interaction patterns in friendships. One hundred respondents' weblogs were analyzed for self-disclosure. Self-reported self-disclosure was positively correlated with number of online friendships and satisfaction with online friendships. Although participants reported having close online friends, they perceived real-life friendships as more likely than online friendships to possess intimacy-promoting interaction patterns. These perceptions did not differ as a function of self-disclosure through blogging, although bloggers who were categorized as higher in disclosure were more satisfied with online friendships than were bloggers who were categorized as lower in disclosure. These results suggest a relationship between self-disclosure through blogging and online relationship satisfaction among women in middle adulthood but that these women perceive real-life friendships as more likely to offer interaction patterns that foster intimacy.

  13. A Delphi Study to Detect Deficiencies and Propose Actions in Real Life Treatment of Neovascular Age-Related Macular Degeneration

    Directory of Open Access Journals (Sweden)

    Alfredo García-Layana

    2014-01-01

    Full Text Available Purpose. Spanish retina specialists were surveyed in order to propose actions to decrease deficiencies in real-life neovascular age macular degeneration treatment (nv-AMD. Methods. One hundred experts, members of the Spanish Vitreoretinal Society (SERV, were invited to complete an online survey of 52 statements about nv-AMD management with a modified Delphi methodology. Four rounds were performed using a 5-point Linkert scale. Recommendations were developed after analyzing the differences between the results and the SERV guidelines recommendations. Results. Eighty-seven specialists completed all the Delphi rounds. Once major potential deficiencies in real-life nv-AMD treatment were identified, 15 recommendations were developed with a high level of agreement. Consensus statements to reduce the burden of the disease included the use of treat and extend regimen and to reduce the amount of diagnostic tests during the loading phase and training technical staff to perform these tests and reduce the time between relapse detection and reinjection, as well as establishing patient referral protocols to outside general ophthalmology clinics. Conclusion. The level of agreement with the final recommendations for nv-AMD treatment among Spanish retinal specialist was high indicating that some actions could be applied in order to reduce the deficiencies in real-life nv-AMD treatment.

  14. Life Skills Training through Situated Learning Experiences: An Alternative Instructional Model

    Science.gov (United States)

    Meyers, Shelly

    2011-01-01

    This article examines the value of situated learning as an alternative to the traditional college course instructional approach for pre-service teachers. The situated learning mode of teaching immerses students in the actual setting, practicing the skills and concepts emphasized in the curriculum. Through a partnership with a college, community…

  15. Serotonin transporter polymorphism modulates neural correlates of real-life joint action. An investigation with functional near-infrared spectroscopy (fNIRS).

    Science.gov (United States)

    Herrmann, M J; Bogon, J; Quester, S; Cordes, A; Stenneken, P; Reif, A; Ehlis, A-C

    2015-04-30

    A functional polymorphism (5-HTTLPR) within the serotonin transporter gene (SERT) has been associated with personality dimensions such as neuroticism, with emotional reactivity to negative events, and with an increased risk of affective disorders. More specifically, the short (S) allele of 5-HTTLPR has been linked to increased amygdala activity and has been identified as a risk allele for depressive disorders. Recently, Homberg and Lesch (2011) urged for a conceptual change in the current deficit-oriented connotation of the 5-HTTLPR S-allele and argued that the S-allele could be considered adaptive in certain contexts. They postulated that S-allele carriers show hypervigilant behavior in social situations and should thus show increased social conformity. Therefore, we tested whether 5-HTTLPR modulates the neural correlates of real-life social joint action through functional near-infrared spectroscopy (fNIRS). Thirty participants, homozygote for 5-HTTLPR, were measured and analyzed while they were involved in a previously published joint-action paradigm, which reliably leads to an activation of the left parietal cortex. We found that homozygote S-allele carriers showed increased inferior parietal lobe activation, compared to the LL-allele carriers for the contrast "joint action greater solo action". Therefore, our results provide evidence for beneficial effects of the S-allele on the neural correlates of social interactions.

  16. How does a collision warning system shape driver's brake response time? The influence of expectancy and automation complacency on real-life emergency braking.

    Science.gov (United States)

    Ruscio, Daniele; Ciceri, Maria Rita; Biassoni, Federica

    2015-04-01

    Brake Reaction Time (BRT) is an important parameter for road safety. Previous research has shown that drivers' expectations can impact RT when facing hazardous situations, but driving with advanced driver assistance systems, can change the way BRT are considered. The interaction with a collision warning system can help faster more efficient responses, but at the same time can require a monitoring task and evaluation process that may lead to automation complacency. The aims of the present study are to test in a real-life setting whether automation compliancy can be generated by a collision warning system and what component of expectancy can impact the different tasks involved in an assisted BRT process. More specifically four component of expectancy were investigated: presence/absence of anticipatory information, previous direct experience, reliability of the device, and predictability of the hazard determined by repeated use of the warning system. Results supply indication on perception time and mental elaboration of the collision warning system alerts. In particular reliable warning quickened the decision making process, misleading warnings generated automation complacency slowing visual search for hazard detection, lack of directed experienced slowed the overall response while unexpected failure of the device lead to inattentional blindness and potential pseudo-accidents with surprise obstacle intrusion. Copyright © 2015 Elsevier Ltd. All rights reserved.

  17. Modeling Of A Monocular, Full-Color, Laser-Scanning, Helmet-Mounted Display for Aviator Situational Awareness

    Science.gov (United States)

    2017-03-27

    USAARL Report No. 2017-10 Modeling of a Monocular, Full-Color, Laser- Scanning, Helmet-Mounted Display for Aviator Situational Awareness By Thomas...Mounted Display for Aviator Situational Awareness N/A N/A N/A N/A N/A N/A Harding, Thomas H. Raatz, Maria E. Martin, John S. Rash, Clarence E. U.S...Huntsville, AL 35806-3302 PM Air Warrior, PEO Soldier Approved for public release; distribution unlimited. The modeling data and analysis presented in

  18. A Closed-Loop Model of Operator Visual Attention, Situation Awareness, and Performance Across Automation Mode Transitions.

    Science.gov (United States)

    Johnson, Aaron W; Duda, Kevin R; Sheridan, Thomas B; Oman, Charles M

    2017-03-01

    This article describes a closed-loop, integrated human-vehicle model designed to help understand the underlying cognitive processes that influenced changes in subject visual attention, mental workload, and situation awareness across control mode transitions in a simulated human-in-the-loop lunar landing experiment. Control mode transitions from autopilot to manual flight may cause total attentional demands to exceed operator capacity. Attentional resources must be reallocated and reprioritized, which can increase the average uncertainty in the operator's estimates of low-priority system states. We define this increase in uncertainty as a reduction in situation awareness. We present a model built upon the optimal control model for state estimation, the crossover model for manual control, and the SEEV (salience, effort, expectancy, value) model for visual attention. We modify the SEEV attention executive to direct visual attention based, in part, on the uncertainty in the operator's estimates of system states. The model was validated using the simulated lunar landing experimental data, demonstrating an average difference in the percentage of attention ≤3.6% for all simulator instruments. The model's predictions of mental workload and situation awareness, measured by task performance and system state uncertainty, also mimicked the experimental data. Our model supports the hypothesis that visual attention is influenced by the uncertainty in system state estimates. Conceptualizing situation awareness around the metric of system state uncertainty is a valuable way for system designers to understand and predict how reallocations in the operator's visual attention during control mode transitions can produce reallocations in situation awareness of certain states.

  19. A Human Sensor Network Framework in Support of Near Real Time Situational Geophysical Modeling

    Science.gov (United States)

    Aulov, O.; Price, A.; Smith, J. A.; Halem, M.

    2013-12-01

    The area of Disaster Management is well established among Federal Agencies such as FEMA, EPA, NOAA and NASA. These agencies have well formulated frameworks for response and mitigation based on near real time satellite and conventional observing networks for assimilation into geophysical models. Forecasts from these models are used to communicate with emergency responders and the general public. More recently, agencies have started using social media to broadcast warnings and alerts to potentially affected communities. In this presentation, we demonstrate the added benefits of mining and assimilating the vast amounts of social media data available from heterogeneous hand held devices and social networks into established operational geophysical modeling frameworks as they apply to the five cornerstones of disaster management - Prevention, Mitigation, Preparedness, Response and Recovery. Often, in situations of extreme events, social media provide the earliest notification of adverse extreme events. However, various forms of social media data also can provide useful geolocated and time stamped in situ observations, complementary to directly sensed conventional observations. We use the concept of a Human Sensor Network where one views social media users as carrying field deployed "sensors" whose posts are the remotely "sensed instrument measurements.' These measurements can act as 'station data' providing the resolution and coverage needed for extreme event specific modeling and validation. Here, we explore the use of social media through the use of a Human Sensor Network (HSN) approach as another data input source for assimilation into geophysical models. Employing the HSN paradigm can provide useful feedback in near real-time, but presents software challenges for rapid access, quality filtering and transforming massive social media data into formats consistent with the operational models. As a use case scenario, we demonstrate the value of HSN for disaster management

  20. Situational Analysis

    OpenAIRE

    Hoover, Kevin D.

    2016-01-01

    Situational analysis (also known as situational logic) was popularized by Karl Popper as an appropriate method for the interpretation of history and as a basis for a scientific social science. It seeks an objective posit ive explanation of behavior through imputing a dominant goal or motive to individuals and then identifying the action that would be objectively appropriate to the situation as the action actually taken. Popper regarded situational analysis as a generalization to all of social...

  1. Assessing Operational Situations

    DEFF Research Database (Denmark)

    Zhang, Xinxin

    different perspectives on situation awareness in the human factor studies and uses the knowledge reflectively for system representation and analysis. The human cognitive activities during complex plant operation and how they perceive a situation and what kind of knowledge has to be established in the human...... operators to perceive and understand the operational situation. The research domain of situation awareness approaches the operational challenges from the human cognition perspective while the presented thesis aims at supporting situation assessment from the system perspective. The thesis has reviewed...... mental model for the operators to be aware of the situations has motivated the utilization of functional representation in system level of situation assessment. The thesis has summarized the MFM syntax and provides detail instructions of how to model by using the modeling technique. A PWR primary system...

  2. 'Doctor' or 'darling'? Decoding the communication partner from ECoG of the anterior temporal lobe during non-experimental, real-life social interaction

    Directory of Open Access Journals (Sweden)

    Johanna eDerix

    2012-09-01

    Full Text Available Human brain processes underlying real-life social interaction in everyday situations have been difficult to study and have, until now, remained largely unknown. Here, we investigated whether electrocorticography (ECoG recorded for pre-neurosurgical diagnostics during the daily hospital life of epilepsy patients could provide a way to elucidate the neural correlates of non-experimental social interaction. We identified time periods in which patients were involved in conversations with either their respective life partners (Condition 1; C1 or attending physicians (Condition 2; C2. These two conditions can be expected to differentially involve subfunctions of social interaction which have been associated with activity in the anterior temporal lobe (ATL, including the temporal poles (TP. Therefore, we specifically focused on ECoG recordings from this brain region and investigated spectral power modulations in the alpha (8-12 Hz and theta (3-5 Hz frequency ranges, which have been previously assumed to play an important role in the processing of social interaction. We hypothesized that brain activity in this region might be sensitive to differences in the two interaction situations and tested whether these differences can be detected by single-trial decoding. Condition-specific effects in both theta and alpha bands were observed: the left and right TP exclusively showed increased power in C1 compared to C2, whereas more posterior parts of the ATL exhibited similar (C1 > C2 and also contrary (C2 > C1 effects. Single-trial decoding accuracies for classification of these effects were highly above chance. Our findings demonstrate that it is possible to study the neural correlates of human social interaction in non-experimental conditions. Decoding the identity of the communication partner and adjusting the speech output accordingly may be useful in the emerging field of brain- machine interfacing for restoration of expressive speech.

  3. A classical treatment of optical tunneling in plasmonic gaps: extending the quantum corrected model to practical situations

    DEFF Research Database (Denmark)

    Esteban, Rubén; Zugarramurdi, Asier; Zhang, Pu

    2015-01-01

    (QCM), that has been introduced to correctly describe the main features of optical transport in plasmonic nanogaps. The basics of this model are explained in detail, and its implementation is extended to include nonlocal effects and address practical situations involving different materials...

  4. Resolving Cognitive Conflict in a Realistic Situation with Modeling Characteristics: Coping with a Changing Reference in Fractions

    Science.gov (United States)

    Shahbari, Juhaina Awawdeh; Peled, Irit

    2015-01-01

    This study investigates the effect of using a realistic situation with modeling characteristics in creating and resolving a cognitive conflict to promote understanding of a changing reference in fraction calculations. The study was conducted among 96 seventh graders divided into 2 experimental groups and 1 control group. The experimental groups…

  5. Resolving Cognitive Conflict in a Realistic Situation with Modeling Characteristics: Coping with a Changing Reference in Fractions

    Science.gov (United States)

    Shahbari, Juhaina Awawdeh; Peled, Irit

    2015-01-01

    This study investigates the effect of using a realistic situation with modeling characteristics in creating and resolving a cognitive conflict to promote understanding of a changing reference in fraction calculations. The study was conducted among 96 seventh graders divided into 2 experimental groups and 1 control group. The experimental groups…

  6. Generalisation of the Clark and Wells Cognitive Model of Social Anxiety to Children's Athletic and Sporting Situations

    Science.gov (United States)

    Vassilopoulos, Stephanos P.; Brouzos, Andreas; Moberly, Nicholas J.; Tsorbatzoudis, Haralambos; Tziouma, Olga

    2017-01-01

    Research has shown that social anxiety generalises to sporting and athletic situations. The present study explored the applicability of the Clark and Wells model of social anxiety--and its metacognitive extension--to sport anxiety. Participants were 290 students aged 11-13 years, who completed measures of sport anxiety, social anxiety, depression…

  7. A Test of Three Basic Assumptions of Situational Leadership® II Model and Their Implications for HRD Practitioners

    Science.gov (United States)

    Zigarmi, Drea; Roberts, Taylor Peyton

    2017-01-01

    Purpose: This study aims to test the following three assertions underlying the Situational Leadership® II (SLII) Model: all four leadership styles are received by followers; all four leadership styles are needed by followers; and if there is a fit between the leadership style a follower receives and needs, that follower will demonstrate favorable…

  8. Psychosocial stress based on public speech in humans: is there a real life/laboratory setting cross-adaptation?

    Science.gov (United States)

    Jezova, D; Hlavacova, N; Dicko, I; Solarikova, P; Brezina, I

    2016-07-01

    Repeated or chronic exposure to stressors is associated with changes in neuroendocrine responses depending on the type, intensity, number and frequency of stress exposure as well as previous stress experience. The aim of the study was to test the hypothesis that salivary cortisol and cardiovascular responses to real-life psychosocial stressors related to public performance can cross-adapt with responses to psychosocial stress induced by public speech under laboratory setting. The sample consisted of 22 healthy male volunteers, which were either actors, more precisely students of dramatic arts or non-actors, students of other fields. The stress task consisted of 15 min anticipatory preparation phase and 15 min of public speech on an emotionally charged topic. The actors, who were accustomed to public speaking, responded with a rise in salivary cortisol as well as blood pressure to laboratory public speech. The values of salivary cortisol, systolic blood pressure and state anxiety were lower in actors compared to non-actors. Unlike non-actors, subjects with experience in public speaking did not show stress-induced rise in the heart rate. Evaluation of personality traits revealed that actors scored significantly higher in extraversion than the subjects in the non-actor group. In conclusion, neuroendocrine responses to real-life stressors in actors can partially cross-adapt with responses to psychosocial stress under laboratory setting. The most evident adaptation was at the level of heart rate responses. The public speech tasks may be of help in evaluation of the ability to cope with stress in real life in artists by simple laboratory testing.

  9. Deceleration during 'real life' motor vehicle collisions – a sensitive predictor for the risk of sustaining a cervical spine injury?

    Directory of Open Access Journals (Sweden)

    Hartwig Erich

    2009-03-01

    Full Text Available Abstract Background The predictive value of trauma impact for the severity of whiplash injuries has mainly been investigated in sled- and crash-test studies. However, very little data exist for real-life accidents. Therefore, the predictive value of the trauma impact as assessed by the change in velocity of the car due to the collision (ΔV for the resulting cervical spine injuries were investigated in 57 cases after real-life car accidents. Methods ΔV was determined for every car and clinical findings related to the cervical spine were assessed and classified according to the Quebec Task Force (QTF. Results In our study, 32 (56% subjects did not complain about symptoms and were therefore classified as QTF grade 0; 25 (44% patients complained of neck pain: 8 (14% were classified as QTF grade I, 6 (10% as QTF grade II, and 11 (19% as QTF grade IV. Only a slight correlation (r = 0.55 was found between the reported pain and ΔV. No relevant correlation was found between ΔV and the neck disability index (r = 0.46 and between ΔV and the QTF grade (r = 0.45 for any of the collision types. There was no ΔV threshold associated with acceptable sensitivity and specificity for the prognosis of a cervical spine injury. Conclusion The results of this study indicate that ΔV is not a conclusive predictor for cervical spine injury in real-life motor vehicle accidents. This is of importance for surgeons involved in medicolegal expertise jobs as well as patients who suffer from whiplash-associated disorders (WADs after motor vehicle accidents. Trial registration The study complied with applicable German law and with the principles of the Helsinki Declaration and was approved by the institutional ethics commission.

  10. UNSCHOOLING AND HOW I BECAME LIBERATED: THE TEENAGE LIBERATION HANDBOOK, QUITTING SCHOOL AND GETTING A REAL LIFE AND EDUCATION 

    Directory of Open Access Journals (Sweden)

    Michael JODAH 

    2017-03-01

    Full Text Available Twenty-five years ago, Grace Llewellyn, a school teacher from Colorado, published The Teenage Liberation Handbook: How to Quit School and Get A Real Life and Education. As a teenager struggling with many issues, including bullying, social isolation and poverty, I concluded that school was largely contributing to my misery — thanks to this book, I finally had the clarity and courage to leave school. This is a retrospective and narrative inquiry on my experiences growing up and the book that has helped transform my life and the lives of other unschoolers. 

  11. Grating-based guided-mode resonance devices and degradation of their performance in real-life conditions

    DEFF Research Database (Denmark)

    Ivinskaya, Aliaksandra; Bergmann, René; Kafka, Jan Robert

    2014-01-01

    Guided-mode resonances in structures having periodicity along at least one dimension were widely employed in the last decade in various optical devices. Initially it was shown that at frequencies close to the second order band gap periodic structures can feature total reflection of light due...... of an infinite periodic structure illuminated by a plane wave. To see how grating-based components can perform in real life we take into account two critical factors: the finite size of the grating and the Gaussian shape of the light source replacing a plane wave. These factors can significantly change...

  12. Real-life practice study of the clinical outcome and cost-effectiveness of photodynamic therapy using methyl aminolevulinate (MAL-PDT) in the management of actinic keratosis and basal cell carcinoma.

    Science.gov (United States)

    Annemans, Lieven; Caekelbergh, Karin; Roelandts, Rik; Boonen, Hugo; Leys, Christoph; Nikkels, Arjen F; van Den Haute, V; van Quickenborne, L; Verhaeghe, Evelien; Leroy, Bernard

    2008-01-01

    Clinical trials have shown that photodynamic therapy using methyl aminolevulinate (MAL-PDT) is an effective treatment for actinic keratosis (AK), and nodular and superficial basal cell carcinoma (nBCC and sBCC) unsuitable for other available therapies. Economic evaluation models have shown that it is a cost effective intervention as well. The objectives of this prospective, observational, one arm study were (i) to verify in a real-life practice study the results obtained in previous clinical trials with MAL-PDT in the treatment of AK, nBCC and sBCC; (ii) to calculate the real-life cost of treatment and validate predictions from an economic evaluation model. Patients with AK and/or BCC were selected according to Belgian reimbursement criteria for treatment with MAL-PDT. Clinical response, cosmetic outcome and tolerability were assessed. MAL-PDT cost was calculated and compared to published model cost data. Data were collected from 247 patients (117 AK, 130 BCC). A complete clinical response was obtained for 83% of AK (85/102) and BCC (97/116) patients. A good or excellent cosmetic outcome was obtained for 95% of AK patients and 93% of BCC patients. Tolerability was good: only 2 patients withdrew for adverse events. Clinical results were similar to previous studies. Total cost of care per patient was euro 381 for AK, euro 318 for nBCC, and euro 298 for sBCC. Total cost per lesion was euro 58 for AK (identical to model prediction), euro 316 for nBCC and euro 178 for sBCC (both within 20% of model prediction). The clinical results of MAL-PDT in this real-life practice study confirm those demonstrated in previous clinical trials. Costs calculated from this study confirm predicted cost-effectiveness in the original model for MAL-PDT in the management of AK and BCC.

  13. [How to initiate, optimise and stop pharmacological treatments: applications in real life].

    Science.gov (United States)

    Scheen, A J

    2015-01-01

    Some patients are exposed to complex clinical situations, which impose a careful analysis of both the indications and contraindications of ongoing pharmacological treatments as well as of the dosing or drug adjustments to be proposed. This article illustrates some problems encountered when a new drug therapy is initiated, when medications with narrow therapeutic window should be supervised and when some drugs should be stopped mainly for safety reasons. The clinical case relates the story of a patient with type 2 diabetes, arterial hypertension and coronary heart disease, who presents a congestive heart failure associated with an episode of atrial fibrillation and a severe renal insufficiency.

  14. From real life to real life

    DEFF Research Database (Denmark)

    Svalgaard, Lotte

    2016-01-01

    In Action Learning programmes, it is held central to work on real business challenges (task) while learning about team and self (process); staying mindful aware of the process is referred to in this paper as ‘double awareness’, and emphasises noticing and acting on process cues while working...... on the task. As business challenges within Action Learning programmes are real, pertinent, and worked with in the context of the organisation, implementation of potential solutions to the challenges is proved to be efficient. However, less is known of how individual participants manage to stay with double....... A study will be shared, where participants have been followed for a period of time after an Action Learning-programme. The study takes a psychodynamic stance and contributes to the knowledge of the individual re-entry by exploring individual, group and organisational dynamics promoting and hindering...

  15. Never blame the umpire - a review of Situation Awareness models and methods for examining the performance of officials in sport.

    Science.gov (United States)

    Neville, Timothy J; Salmon, Paul M

    2016-07-01

    As sport becomes more complex, there is potential for ergonomics concepts to help enhance the performance of sports officials. The concept of Situation Awareness (SA) appears pertinent given the requirement for officials to understand what is going on in order to make decisions. Although numerous models exist, none have been applied to examine officials, and only several recent examples have been applied to sport. This paper examines SA models and methods to identify if any have applicability to officials in sport (OiS). Evaluation of the models and methods identified potential applications of individual, team and systems models of SA. The paper further demonstrates that the Distributed Situation Awareness model is suitable for studying officials in fastball sports. It is concluded that the study of SA represents a key area of multidisciplinary research for both ergonomics and sports science in the context of OiS. Practitioner Summary: Despite obvious synergies, applications of cognitive ergonomics concepts in sport are sparse. This is especially so for Officials in Sport (OiS). This article presents an evaluation of Situation Awareness models and methods, providing practitioners with guidance on which are the most suitable for OiS system design and evaluation.

  16. Machine Learning Based Multi-Physical-Model Blending for Enhancing Renewable Energy Forecast -- Improvement via Situation Dependent Error Correction

    Energy Technology Data Exchange (ETDEWEB)

    Lu, Siyuan; Hwang, Youngdeok; Khabibrakhmanov, Ildar; Marianno, Fernando J.; Shao, Xiaoyan; Zhang, Jie; Hodge, Bri-Mathias; Hamann, Hendrik F.

    2015-07-15

    With increasing penetration of solar and wind energy to the total energy supply mix, the pressing need for accurate energy forecasting has become well-recognized. Here we report the development of a machine-learning based model blending approach for statistically combining multiple meteorological models for improving the accuracy of solar/wind power forecast. Importantly, we demonstrate that in addition to parameters to be predicted (such as solar irradiance and power), including additional atmospheric state parameters which collectively define weather situations as machine learning input provides further enhanced accuracy for the blended result. Functional analysis of variance shows that the error of individual model has substantial dependence on the weather situation. The machine-learning approach effectively reduces such situation dependent error thus produces more accurate results compared to conventional multi-model ensemble approaches based on simplistic equally or unequally weighted model averaging. Validation over an extended period of time results show over 30% improvement in solar irradiance/power forecast accuracy compared to forecasts based on the best individual model.

  17. Developing a Laboratory Model for the Professional Preparation of Future Science Teachers: A Situated Cognition Perspective

    Science.gov (United States)

    Sweeney, Aldrin E.; Paradis, Jeffrey A.

    2004-01-01

    Although laboratory activities are widely acknowledged as being fundamental to the teaching of science, many secondary science school teachers have limited knowledge of how to design and run effective teaching laboratories. Utilising a situated cognition theoretical framework, we discuss our collaborative efforts to develop a laboratory based…

  18. Temporal aspects of user experience: Models and methods beyond a single use situation

    NARCIS (Netherlands)

    Kujala, S.; Minge, M.; Pohlmeyer, A.E.; Vogel, M.

    2012-01-01

    User Experience (UX) is an ongoing process and should not be limited to a single use situation. However, this is unfortunately often the case in HCI research. The goal of this workshop is to deepen and expand available knowledge with respect to temporal dynamics of UX. Relevant aspects will be the u

  19. Evolutionistic or revolutionary paths? A PACS maturity model for strategic situational planning.

    NARCIS (Netherlands)

    Wetering, R. van de; Batenburg, R.; Lederman, R.

    2010-01-01

    PURPOSE: While many hospitals are re-evaluating their current Picture Archiving and Communication System (PACS), few have a mature strategy for PACS deployment. Furthermore, strategies for implementation, strategic and situational planning methods for the evolution of PACS maturity are scarce in the

  20. Description of Anomalous Noise Events for Reliable Dynamic Traffic Noise Mapping in Real-Life Urban and Suburban Soundscapes

    Directory of Open Access Journals (Sweden)

    Francesc Alías

    2017-02-01

    Full Text Available Traffic noise is one of the main pollutants in urban and suburban areas. European authorities have driven several initiatives to study, prevent and reduce the effects of exposure of population to traffic. Recent technological advances have allowed the dynamic computation of noise levels by means of Wireless Acoustic Sensor Networks (WASN such as that developed within the European LIFE DYNAMAP project. Those WASN should be capable of detecting and discarding non-desired sound sources from road traffic noise, denoted as anomalous noise events (ANE, in order to generate reliable noise level maps. Due to the local, occasional and diverse nature of ANE, some works have opted to artificially build ANE databases at the cost of misrepresentation. This work presents the production and analysis of a real-life environmental audio database in two urban and suburban areas specifically conceived for anomalous noise events’ collection. A total of 9 h 8 min of labelled audio data is obtained differentiating among road traffic noise, background city noise and ANE. After delimiting their boundaries manually, the acoustic salience of the ANE samples is automatically computed as a contextual signal-to-noise ratio (SNR. The analysis of the real-life environmental database shows high diversity of ANEs in terms of occurrences, durations and SNRs, as well as confirming both the expected differences between the urban and suburban soundscapes in terms of occurrences and SNRs, and the rare nature of ANE.

  1. A Robust Epoxy Resins @ Stearic Acid-Mg(OH)2 Micronanosheet Superhydrophobic Omnipotent Protective Coating for Real-Life Applications.

    Science.gov (United States)

    Si, Yifan; Guo, Zhiguang; Liu, Weimin

    2016-06-29

    Superhydrophobic coating has extremely high application value and practicability. However, some difficult problems such as weak mechanical strength, the need for expensive toxic reagents, and a complex preparation process are all hard to avoid, and these problems have impeded the superhydrophobic coating's real-life application for a long time. Here, we demonstrate one kind of omnipotent epoxy resins @ stearic acid-Mg(OH)2 superhydrophobic coating via a simple antideposition route and one-step superhydrophobization process. The whole preparation process is facile, and expensive toxic reagents needed. This omnipotent coating can be applied on any solid substrate with great waterproof ability, excellent mechanical stability, and chemical durability, which can be stored in a realistic environment for more than 1 month. More significantly, this superhydrophobic coating also has four protective abilities, antifouling, anticorrosion, anti-icing, and flame-retardancy, to cope with a variety of possible extreme natural environments. Therefore, this omnipotent epoxy resins @ stearic acid-Mg(OH)2 superhydrophobic coating not only satisfies real-life need but also has great application potential in many respects.

  2. Reversal of Dabigatran Using Idarucizumab in a Septic Patient with Impaired Kidney Function in Real-Life Practice

    Directory of Open Access Journals (Sweden)

    Thomas C. Sauter

    2016-01-01

    Full Text Available Background. Immediate reversal of anticoagulation is essential when facing severe bleeding or emergency surgery. Although idarucizumab is approved for the reversal of dabigatran in many countries, clinical experiences are lacking, particularly in special patient-populations such as sepsis and impaired renal function. Case Presentation. We present the case of a 67-year-old male septic patient with a multilocular facial abscess and chronic kidney disease (GFR 36.5 mL/min. Thrombin time (TT and activated partial thromboplastin time (aPTT 15 hours after the last intake of 150 mg dabigatran were both prolonged (>120 sec, resp., 61 sec, as well as unbound dabigatran concentration (119.05 ng/mL. Before immediate emergency surgery dabigatran was antagonised using idarucizumab 2 × 2.5 g. Dabigatran concentration was not detectable 10 min after idarucizumab administration (<30 ng/mL. TT and aPTT time were normalised (16.2 sec, resp., 30.2 sec. Sepsis was controlled after surgery and kidney function remained stable. In the absence of postoperative bleeding, dabigatran was restarted 36 hours after admission. Conclusion. Idarucizumab successfully reversed the effect of dabigatran in real-life practice in a patient with sepsis and renal impairment and allowed emergency surgery with normal haemostasis. Efficacy and safety in real-life practice will nevertheless require prospective registries monitoring.

  3. Theory vs. "Real Life" Instructional Media Design: A Primer for Those New to the Field.

    Science.gov (United States)

    Saito, Yoshio

    1982-01-01

    Presents a model for instructional media design, adapted from the theoretical model and viewed to work well with reasonable effort and time. An example of the model in use is provided to give evidence of reasonableness. Outlines of both the theoretical and adapted models are provided. (MP)

  4. Toward an engineering model for the aerodynamic forces acting on wind turbine blades in quasisteady standstill and blade installation situations

    DEFF Research Database (Denmark)

    Gaunaa, Mac; Heinz, Joachim Christian; Skrzypinski, Witold Robert

    2016-01-01

    The crossflow principle is one of the key elements used in engineering models for prediction of the aerodynamic loads on wind turbine blades in standstill or blade installation situations, where the flow direction relative to the wind turbine blade has a component in the direction of the blade span...... direction. In the present work, the performance of the crossflow principle is assessed on the DTU 10MW reference blade using extensive 3D CFD calculations. Analysis of the computational results shows that there is only a relatively narrow region in which the crossflow principle describes the aerodynamic...... for the key aerodynamic loads in crossflow situations. The general validity of this model for other blade shapes should be investigated in subsequent works....

  5. Interventional cardiology, where real life and science do not necessarily meet.

    Science.gov (United States)

    Meier, Bernhard

    2016-07-01

    Evidence-based diagnosis, decision-making, and therapy appear a must these days. Generating and publishing evidence is a tedious job according to ever new and tightened research practice regulations. Rules will never prevent the typical human behaviour from showing the new thing to be shinier and the old thing dustier than they really are. The medical community is solicited to concoct a meal that is gullible for patients, authorities, and third-party payers out of the available evidence (after applying some conversion factors correcting the common bias of the researchers), anticipation of what will be the evidence tomorrow, common sense, and digested experience. Examples of misguidance by poorly produced or misinterpreted evidence are plentiful in interventional cardiology as they are in other disciplines. Coronary stents, for instance, were first underestimated due to the fact that they were generally used in bailout situations where the outcome remained rather dismal in spite of the salvaging potential of stents. Then they were overused quite uncritically rather to the detriment of the patient. Now with the high quality of the modern drug-eluting stents (DESs), the overuse persists but is no longer a concern. However, the enhanced potential of DESs compared with bare-metal stents was poorly exploited for >10 years because of reports that slipped through the meshes of good review and publication practice to convey the untenable message that bare-metal stents were preferable in many situations. As other examples, use of the fractional flow reserve (FFR) for decision-making has to be questioned despite prominently published reports recommending it. Fixing a lesion is today easier and hardly more complication prone than assessing it with the FFR. Closure of the patent foramen ovale may never be properly applied, because the collection of the understandably requested evidence takes decades, a follow-up duration that makes research unattractive to physicians and

  6. Becoming popular: Interpersonal emotion regulation predicts relationship formation in real life social networks

    Directory of Open Access Journals (Sweden)

    Karen eNiven

    2015-09-01

    Full Text Available Building relationships is crucial for satisfaction and success, especially when entering new social contexts. In the present paper, we investigate whether attempting to improve others’ feelings helps people to make connections in new networks. In Study 1, a social network study following new networks of people for a twelve-week period indicated that use of interpersonal emotion regulation (IER strategies predicted growth in popularity, as indicated by other network members’ reports of spending time with the person, in work and non-work interactions. In Study 2, linguistic analysis of the tweets from over 8000 Twitter users from formation of their accounts revealed that use of IER predicted greater popularity in terms of the number of followers gained. However, not all types of IER had positive effects. Behavioral IER strategies (which use behavior to reassure or comfort in order to regulate affect were associated with greater popularity, while cognitive strategies (which change a person’s thoughts about his or her situation or feelings in order to regulate affect were negatively associated with popularity. Our findings have implications for our understanding of how new relationships are formed, highlighting the important the role played by intentional emotion regulatory processes.

  7. Becoming popular: interpersonal emotion regulation predicts relationship formation in real life social networks.

    Science.gov (United States)

    Niven, Karen; Garcia, David; van der Löwe, Ilmo; Holman, David; Mansell, Warren

    2015-01-01

    Building relationships is crucial for satisfaction and success, especially when entering new social contexts. In the present paper, we investigate whether attempting to improve others' feelings helps people to make connections in new networks. In Study 1, a social network study following new networks of people for a 12-week period indicated that use of interpersonal emotion regulation (IER) strategies predicted growth in popularity, as indicated by other network members' reports of spending time with the person, in work and non-work interactions. In Study 2, linguistic analysis of the tweets from over 8000 Twitter users from formation of their accounts revealed that use of IER predicted greater popularity in terms of the number of followers gained. However, not all types of IER had positive effects. Behavioral IER strategies (which use behavior to reassure or comfort in order to regulate affect) were associated with greater popularity, while cognitive strategies (which change a person's thoughts about his or her situation or feelings in order to regulate affect) were negatively associated with popularity. Our findings have implications for our understanding of how new relationships are formed, highlighting the important the role played by intentional emotion regulatory processes.

  8. Situating Engagement

    DEFF Research Database (Denmark)

    Korn, Matthias

    can participate in the world. We experience a new participatory culture on the go. These developments offer new possibilities for civic engagement in participatory land use planning: to engage people where they are. This dissertation coins the notion of situated engagement, which seeks to ’situate......’ civic engagement activities in those spatial contexts that are at stake in land use planning. This approach enables engagement activities to be better integrated with people’s everyday lived experiences through connecting to the places that are personally meaningful and relevant to them. A ’research...... through design’ approach is applied across four participatory design experiments to explore how to design for situated engagement in land use planning. A notion of a situated engagement infrastructure made up of mobile, stationary, ubiquitous, and remote systems frames the design experiments suggesting...

  9. Situated Transgressiveness

    DEFF Research Database (Denmark)

    Muhr, Sara Louise; Sullivan, Katie Rose; Rich, Craig

    2016-01-01

    and perceives her trans body and gender identity. In particular, our analysis centres on how Claire's lived experience of personal and professional life shift across three different situated contexts, each enabling and constraining opportunities for political transgression. Our findings contribute to existing......This study investigates the lived experience of one transwoman, Claire, a public advocate and a manager with client services responsibilities. We examine Claire's story in order to discuss how situated contexts, such as different roles, locales and interactions, shape the way she experiences...... conversations within queer theory, transgender and organization studies by highlighting how situated contexts mediate the political potential of queer bodies at work. By developing the concept ‘situated transgressiveness’, this article challenges notions of transgender as a stable, ideal disruptive category...

  10. Situated Transgressiveness

    DEFF Research Database (Denmark)

    Muhr, Sara Louise; Sullivan, Katie Rose; Rich, Craig

    2016-01-01

    conversations within queer theory, transgender and organization studies by highlighting how situated contexts mediate the political potential of queer bodies at work. By developing the concept ‘situated transgressiveness’, this article challenges notions of transgender as a stable, ideal disruptive category...... and advances a more contextually sensitive approach to understanding the contingency of transgender lives and politics. Such insights are important in facilitating more nuanced understandings of the situatedness of transgression and transgender bodies within work and professional settings....

  11. The importance of shared mental models and shared situation awareness for transforming robots from tools to teammates

    Science.gov (United States)

    Ososky, Scott; Schuster, David; Jentsch, Florian; Fiore, Stephen; Shumaker, Randall; Lebiere, Christian; Kurup, Unmesh; Oh, Jean; Stentz, Anthony

    2012-06-01

    Current ground robots are largely employed via tele-operation and provide their operators with useful tools to extend reach, improve sensing, and avoid dangers. To move from robots that are useful as tools to truly synergistic human-robot teaming, however, will require not only greater technical capabilities among robots, but also a better understanding of the ways in which the principles of teamwork can be applied from exclusively human teams to mixed teams of humans and robots. In this respect, a core characteristic that enables successful human teams to coordinate shared tasks is their ability to create, maintain, and act on a shared understanding of the world and the roles of the team and its members in it. The team performance literature clearly points towards two important cornerstones for shared understanding of team members: mental models and situation awareness. These constructs have been investigated as products of teams as well; amongst teams, they are shared mental models and shared situation awareness. Consequently, we are studying how these two constructs can be measured and instantiated in human-robot teams. In this paper, we report results from three related efforts that are investigating process and performance outcomes for human robot teams. Our investigations include: (a) how human mental models of tasks and teams change whether a teammate is human, a service animal, or an advanced automated system; (b) how computer modeling can lead to mental models being instantiated and used in robots; (c) how we can simulate the interactions between human and future robotic teammates on the basis of changes in shared mental models and situation assessment.

  12. Detecting breakpoints in artificially modified- and real-life time series using three state-of-the-art methods

    Directory of Open Access Journals (Sweden)

    Topál Dániel

    2016-02-01

    Full Text Available Time series often contain breakpoints of different origin, i.e. breakpoints, caused by (i shifts in trend, (ii other changes in trend and/or, (iii changes in variance. In the present study, artificially generated time series with white and red noise structures are analyzed using three recently developed breakpoint detection methods. The time series are modified so that the exact “locations” of the artificial breakpoints are prescribed, making it possible to evaluate the methods exactly. Hence, the study provides a deeper insight into the behaviour of the three different breakpoint detection methods. Utilizing this experience can help solving breakpoint detection problems in real-life data sets, as is demonstrated with two examples taken from the fields of paleoclimate research and petrology.

  13. High-Resolution Single-Molecule Fluorescence Imaging of Zeolite Aggregates within Real-Life Fluid Catalytic Cracking Particles**

    Science.gov (United States)

    Ristanović, Zoran; Kerssens, Marleen M; Kubarev, Alexey V; Hendriks, Frank C; Dedecker, Peter; Hofkens, Johan; Roeffaers, Maarten B J; Weckhuysen, Bert M

    2015-01-01

    Fluid catalytic cracking (FCC) is a major process in oil refineries to produce gasoline and base chemicals from crude oil fractions. The spatial distribution and acidity of zeolite aggregates embedded within the 50–150 μm-sized FCC spheres heavily influence their catalytic performance. Single-molecule fluorescence-based imaging methods, namely nanometer accuracy by stochastic chemical reactions (NASCA) and super-resolution optical fluctuation imaging (SOFI) were used to study the catalytic activity of sub-micrometer zeolite ZSM-5 domains within real-life FCC catalyst particles. The formation of fluorescent product molecules taking place at Brønsted acid sites was monitored with single turnover sensitivity and high spatiotemporal resolution, providing detailed insight in dispersion and catalytic activity of zeolite ZSM-5 aggregates. The results point towards substantial differences in turnover frequencies between the zeolite aggregates, revealing significant intraparticle heterogeneities in Brønsted reactivity. PMID:25504139

  14. The real-life experience with cardiovascular complications in the first dose of fingolimod for multiple sclerosis

    Directory of Open Access Journals (Sweden)

    Yara Dadalti Fragoso

    2014-09-01

    Full Text Available Fingolimod is a new and efficient treatment for multiple sclerosis (MS. The drug administration requires special attention to the first dose, since cardiovascular adverse events can be observed during the initial six hours of fingolimod ingestion. The present study consisted of a review of cardiovascular data on 180 patients with MS receiving the first dose of fingolimod. The rate of bradycardia in these patients was higher than that observed in clinical trials with very strict inclusion criteria for patients. There were less than 10% of cases requiring special attention, but no fatal cases. All but one patient continued the treatment after this initial dose. This is the first report on real-life administration of fingolimod to Brazilian patients with MS, and one of the few studies with these characteristics in the world.

  15. Real-life effectiveness of smoking-cessation treatments in general practice clinics in Denmark. The Escape Smoke project

    DEFF Research Database (Denmark)

    Poulsen, Peter Bo; Spillemose, Heidi; Nielsen, Gerda

    2015-01-01

    BACKGROUND: The smoking prevalence has not decreased in the last years in Denmark. General practice (GP) offers smoking cessation (SC) treatment. Studies of real-life effectiveness of daily practice SC-activities from the GP-setting opposed to efficacy results from randomized clinical trials......-clinics recruited 515 (273 females, 20% COPD) daily smokers being moderately nicotine dependent and heavy smoking (19 cigarettes/day). Receiving intensive advice, 74% did use SC-medicine paid out-of-pocket (1/3 NRT and 2/3 prescription-based). After 6 months, 187 participants had remained abstinent (36%). Adjusted......-medicine were independent significant predictors for long-term abstinence. CONCLUSIONS: Smoking cessation in Danish GP-clinics with some prior SC-activity can result in rather high long-term quit rates, especially when combining counseling and prescription-based SC-medicine. The effectiveness of prescription...

  16. COLLISION AVOIDANCE DECISION- MAKING MODEL OF MULTI-AGENTS IN VIRTUAL DRIVING ENVIRONMENT WITH ANALYTIC HIERARCHY PROCESS

    Institute of Scientific and Technical Information of China (English)

    LU Hong; YI Guodong; TAN Jianrong; LIU Zhenyu

    2008-01-01

    Collision avoidance decision-making models of multiple agents in virtual driving environ- ment are studied. Based on the behavioral characteristics and hierarchical structure of the collision avoidance decision-making in real life driving, delphi approach and mathematical statistics method are introduced to construct pair-wise comparison judgment matrix of collision avoidance decision choices to each collision situation. Analytic hierarchy process (AHP) is adopted to establish the agents' collision avoidance decision-making model. To simulate drivers' characteristics, driver factors are added to categorize driving modes into impatient mode, normal mode, and the cautious mode. The results show that this model can simulate human's thinking process, and the agents in the virtual environment can deal with collision situations and make decisions to avoid collisions without intervention. The model can also reflect diversity and uncertainty of real life driving behaviors, and solves the multi-objective, multi-choice ranking priority problem in multi-vehicle collision scenarios. This collision avoidance model of multi-agents model is feasible and effective, and can provide richer and closer-to-life virtual scene for driving simulator, reflecting real-life traffic environment more truly, this model can also promote the practicality of driving simulator.

  17. Taxonomy of high-risk situations for alcohol relapse: evolution and development of a cognitive-behavioral model.

    Science.gov (United States)

    Marlatt, G A

    1996-12-01

    The purpose of this paper is to provide an historical overview of the development of the taxonomy of high-risk situations for relapse in patients receiving abstinence-based treatment for alcoholism. Research conducted during the 1970s on determinants of relapse is briefly reviewed, beginning with a preliminary analysis of relapse patterns in alcoholics treated with aversion therapy. Theoretical foundations underlying the development of the taxonomy are then discussed with an emphasis on social-learning theory and its implications for cognitive-behavioral interventions for relapse prevention. Findings supporting the efficacy of coping-skills training for high-risk relapse situations, based on a prospective treatment outcome study for inpatient alcoholics, are also presented in support of the clinical validity of the relapse model. The paper concludes with a description of the refined and extended taxonomy of high-risk situations and the associated cognitive-behavioral model of relapse described in the Marlatt & Gordon (1985) text on relapse prevention.

  18. The frequency and determinants of liver stiffness measurement failure: a retrospective study of "real-life" 38,464 examinations.

    Directory of Open Access Journals (Sweden)

    Dong Ji

    Full Text Available To investigate the frequency and determinants of liver stiffness measurement (LSM failure by means of FibroScan in "real-life" Chinese patients.A total of 38,464 "real-life" Chinese patients in 302 military hospital of China through the whole year of 2013, including asymptomatic carrier, chronic hepatitis B, chronic hepatitis C, liver cirrhosis (LC, alcoholic liver disease, autoimmune liver disease, hepatocellular carcinoma (HCC and other, were enrolled, their clinical and biological parameters were retrospectively investigated. Liver fibrosis was evaluated by FibroScan detection. S probe (for children with height less than 1.20 m and M probe (for adults were used. LSM failure defined as zero valid shots (unsuccessful LSM, or the ratio of the interquartile range to the median of 10 measurements (IQR/M greater than 0.30 plus median LSM greater or equal to 7.1 kPa (unreliable LSM.LSM failure occurred in 3.34% of all examinations (1286 patients out of 38,464, among them, there were 958 cases (2.49% with unsuccessful LSM, and 328 patients (0.85% with unreliable LSM. Statistical analyses showed that LSM failure was independently associated with body mass index (BMI greater than 30 kg/m(2, female sex, age greater than 50 years, intercostal spaces (IS less than 9 mm, decompensated liver cirrhosis and HCC patients. There were no significant differences among other diseases. By changing another skilled operator, success was achieved on 301 cases out of 1286, which reduced the failure rate to 2.56%, the decrease was significant (P<0.0001.The principal reasons of LSM failure are ascites, obesity and narrow of IS. The failure rates of HCC, decompensated LC, elder or female patients are higher. These results emphasize the need for adequate operator training, technological improvements and optimal criteria for specific patient subpopulations.

  19. Efficacy and safety of glucosamine sulfate in the management of osteoarthritis: Evidence from real-life setting trials and surveys.

    Science.gov (United States)

    Bruyère, Olivier; Altman, Roy D; Reginster, Jean-Yves

    2016-02-01

    The European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) treatment algorithm recommends chronic symptomatic slow-acting drugs for osteoarthritis (SYSADOAs) including glucosamine sulfate (GS) and chondroitin sulfate (CS) as first-line therapy for knee osteoarthritis (OA). Numerous studies are published on the use of SYSADOAs in OA; however, the efficacy of this class is still called into question largely due to the regulatory status, labeling and availability of these medications which differ substantially across the world. Examination of the evidence for the prescription patented crystalline GS (pCGS) formulation at a dose of 1500mg once-daily demonstrates superiority over other GS and glucosamine hydrochloride (GH) formulations and dosage regimens. Thus, the ESCEO task force advocates differentiation of prescription pCGS over other glucosamine preparations. Long-term clinical trials and real-life studies show that pCGS may delay joint structural changes, suggesting potential benefit beyond symptom control when used early in the management of knee OA. Real-life pharmacoeconomic studies demonstrate a long-term reduction in the need for additional pain analgesia and non-steroidal anti-inflammatory drugs (NSAIDs) with pCGS, with a significant reduction of over 50% in costs associated with medications, healthcare consultations and examinations over 12 months. Furthermore, treatment with pCGS for at least 12 months leads to a reduction in the need for total joint replacement for at least 5 years following treatment cessation. Thus, pCGS (1500mg od) is a logical choice to maximize clinical benefit in OA patients, with demonstrated medium-term control of pain and lasting impact on disease progression.

  20. The use of new aceclofenac dosage forms in patients with osteoarthrosis in real-life clinical practice

    Directory of Open Access Journals (Sweden)

    Lyudmila Ivanovna Alekseeva

    2014-01-01

    Full Text Available A new convenient dosage form of aceclofenac (sashet bags has recently been launched on the Russian market. The powder in a single sashet bag weighs 3 g, which corresponds to 100 mg of the active ingredient per tablet. A prospective study (including evaluation of the effectiveness and safety of the sashet form of aceclofenac in real-life clinical practice was carried out in 40 outpatients with osteoarthrosis (OA of the knee and hip joints during 2 weeks. A clear pain relief by 25% vs the beginning of therapy was observed; joint stiffness decreased by 34%; joint function improved by 17%; and the total WOMAC score decreased by 18% by the end of the therapy (262.7±127.7 vs 198.5±111.6; 88.5±42.21vs 57.7±32.6; 789.9±307.2 vs 650.6±242.6 and 1087.7±369.3 vs 886.4±326.0, p<0.05, respectively, in all cases. The results of our surveillance study in real-life clinical practice have shown that sashet aceclofenac rapidly relieves pain and reduces joint stiffness, thus improving the functional condition of joints. Adverse effects related to the gastrointestinal tract were observed in only one (2.5% patient when using sashet aceclofenac. The drug in this dosage form can be recommended as an effective and safe agent, especially for patients who typically receive non-steroidal anti-inflammatory drugs in liquid forms.

  1. Steering through the murky waters of a scientific conflict: situated and symbolic models of clinical cognition.

    Science.gov (United States)

    Patel, V L; Kaufman, D R; Arocha, J F

    1995-10-01

    The situated action perspective, which embraces a diversity of views, challenges several of the fundamental assumptions of the symbolic information-processing framework underlying cognitive science and artificial intelligence. In this paper, we consider the following issues; symbolic representations, plans and actions, distributed cognition, and the transfer of learning. We evaluate each of these issues in terms of research and theories in clinical cognition and examine the implications for education and training, and for the integration of intelligent systems in medical practice. We argue for a reconceptualization of the symbolic framework in terms of the way the role of internal representations and cognitive activities are perceived. However, symbolic representations are integral to medical cognition and should continue to be central in any theoretical framework. A re-examination of cognitive science in medicine in terms of the relationship among physicians, technology, and the workplace could prove to be constructive in bridging the gap between theory and practice.

  2. Causal attributions, real life-events and personality characteristics : a preliminary study

    NARCIS (Netherlands)

    SANDERMAN, R

    1986-01-01

    The learned-helplessness model has been given much attention recently. In this article some issues are briefly reviewed, the main purpose of this study was, however, to determine the relationship between causal attributions and personality characteristics, symptoms and feelings of well-being.

  3. Causal attributions, real life-events and personality characteristics : a preliminary study

    NARCIS (Netherlands)

    SANDERMAN, R

    1986-01-01

    The learned-helplessness model has been given much attention recently. In this article some issues are briefly reviewed, the main purpose of this study was, however, to determine the relationship between causal attributions and personality characteristics, symptoms and feelings of well-being. Althou

  4. Optimized Design of Materialized Views in a Real-Life Data Warehousing Environment

    NARCIS (Netherlands)

    Chan, G.K.Y.; Li, Q.; Feng, L.; Gay, R.K.L.

    2001-01-01

    In this paper, we describe the design of a data warehousing system for an engineering company ‘R’. This system aims to assist users in retrieving data for business analysis in an efficient manner. The structural design of this data warehousing system employs the dimensional modeling concepts of star

  5. Simulating Real Life: Enhancing Social Work Education on Alcohol Screening and Brief Intervention

    Science.gov (United States)

    Osborne, Victoria A.; Benner, Kalea; Sprague, Debra J.; Cleveland, Ivy N.

    2016-01-01

    Social work students typically use role play with student colleagues to practice clinical intervention skills. Practice with simulated clients (SCs) rather than classmates changes the dynamics of the role play and may improve learning. This is the first known study to employ the SC model in substance use assessment in social work education. Social…

  6. Deadhead Trip Minimization in City Bus Transportation: A Real Life Application

    Directory of Open Access Journals (Sweden)

    Efendi Nasibov

    2013-04-01

    Full Text Available The quality of public transportation services is one of the most important performance indicators of modern urban policies for both planning and implementation aspects. Therefore, along with the size of the city, the significance of appropriate cost evaluation and optimization of all related transportation activities increases as well. One of the most important cost factors for the public transport agencies is naturally the fuel consumption of the vehicles. In this study, the attention is focused on the metropolitan bus transport service. The specific aim is to minimize a significant portion of total fuel utilization that occurs due to the so called deadhead trip or dead mileage, which is defined as the idle distance covered by the vehicle between the garage and the route terminal stops without carrying any passengers. In this study, the results of four mathematical models for minimizing the total deadhead trip distance covered in city bus services of Izmir are presented. The models vary due to the inclusion of garage capacity restrictions or operator distinction for supporting both operational and strategical decisions. All models are applied to the recent bus schedule data, which consist of 293 routes, 1,424 buses and 10 garages, for obtaining the optimal route bus-garage allocations and garage capacities. The results of the Decentralized-Capacitated model, which is appropriate for quick implementation, promise a 7.8% reduction in total dead mileage. While on the other hand, if all garage capacities can be expanded and the bus service is maintained only by one operator as modelled in the Centralized-Uncapacitated case, even a 31.4% improvement is possible in the long term. The environmental gains as well as the financial benefits to be achieved when the solutions are actually implemented, justify the practical contribution of the study.

  7. Situational awareness of influenza activity based on multiple streams of surveillance data using multivariate dynamic linear model.

    Directory of Open Access Journals (Sweden)

    Eric H Y Lau

    Full Text Available BACKGROUND: Multiple sources of influenza surveillance data are becoming more available; however integration of these data streams for situational awareness of influenza activity is less explored. METHODS AND RESULTS: We applied multivariate time-series methods to sentinel outpatient and school absenteeism surveillance data in Hong Kong during 2004-2009. School absenteeism data and outpatient surveillance data experienced interruptions due to school holidays and changes in public health guidelines during the pandemic, including school closures and the establishment of special designated flu clinics, which in turn provided 'drop-in' fever counts surveillance data. A multivariate dynamic linear model was used to monitor influenza activity throughout epidemics based on all available data. The inferred level followed influenza activity closely at different times, while the inferred trend was less competent with low influenza activity. Correlations between inferred level and trend from the multivariate model and reference influenza activity, measured by the product of weekly laboratory influenza detection rates and weekly general practitioner influenza-like illness consultation rates, were calculated and compared with those from univariate models. Over the whole study period, there was a significantly higher correlation (ρ = 0.82, p≤0.02 for the inferred trend based on the multivariate model compared to other univariate models, while the inferred trend from the multivariate model performed as well as the best univariate model in the pre-pandemic and the pandemic period. The inferred trend and level from the multivariate model was able to match, if not outperform, the best univariate model albeit with missing data plus drop-in and drop-out of different surveillance data streams. An overall influenza index combining level and trend was constructed to demonstrate another potential use of the method. CONCLUSIONS: Our results demonstrate the

  8. Outcomes of FLEXIBLE Assertive Community Treatment (FACT) Implementation: A Prospective Real Life Study.

    Science.gov (United States)

    Nugter, M Annet; Engelsbel, Fabiana; Bähler, Michiel; Keet, René; van Veldhuizen, Remmers

    2016-11-01

    This study aimed to investigate social and clinical outcomes and use of care during and after implementation of FLEXIBLE Assertive Community Treatment (ACT). Three teams and 372 patients were involved. Model fidelity, clinical and social assessments were performed at baseline and after 1 and 2 years. Use of care was registered continuously. Model fidelity was good at the end of the study. Data showed much variation between patients in number and duration of ACT periods. Statistically significant improvements were found in compliance, unmet needs and quality of life. Improvement of quality of life and functioning was related to duration of ACT. The percentage of remissions increased with 9 %. The number of admissions, admission days and face to face contacts differed between ACT and non-ACT patients, but generally decreased. Findings suggest that implementation of FACT results in a more flexible adaptation of care to the needs of the patients.

  9. Causal attributions, real life-events and personality characteristics: a preliminary study

    OpenAIRE

    Sanderman, R.

    1986-01-01

    The learned-helplessness model has been given much attention recently. In this article some issues are briefly reviewed, the main purpose of this study was, however, to determine the relationship between causal attributions and personality characteristics, symptoms and feelings of well-being. Although causal attribution style is considered a trait-like concept, this can not be substantiated by the results of the current study. It is concluded that a refinement of the learned-helplessness mode...

  10. A Reliance on Recollection for Emotional Real-life Scenes: Evidence from Source Retrieval Task

    OpenAIRE

    Bennett, Emily E.

    2011-01-01

    The diverse effects of emotion on human memory is a topic of discussion that has brought about much interest within psychology (Cardwell, Clark and Meldrum, 2004) with a particular emphasis on how further understanding of its influence can aid our knowledge about the structure of underlying memory systems. In recognition memory research, dual-process models propose that judgements can be based on two independent retrieval processes: “familiarity”, based on the perception of a memory’s strengt...

  11. Situation Songs

    DEFF Research Database (Denmark)

    Kolar-Borsky, Agnes; Holck, Ulla

    2014-01-01

    the therapeutic relationship; to enhance experience and development in the fields of emotion, behavior, expression and social skills; to express messages in language and to give structure to the child. The overall aim behind the use of situation songs is to offer essential experiences to the child in order......The aim of this study was to survey the various therapeutic intentions behind the use of one particular improvisation method applied in pediatric music therapy, called the situation song (from the German term “Situationslied”- Plahl & Koch-Temming, 2008, p. 180). According to Plahl & Koch...... author’s clinical experience with situation songs (preunderstandings), a systematic analysis of relevant literature, followed by semi-structured interviews with three music therapists from Denmark, Austria and Germany. A flexible investigation approach was used, following hermeneutic principles...

  12. Situation Songs

    DEFF Research Database (Denmark)

    Kolar-Borsky, Agnes; Holck, Ulla

    2014-01-01

    author’s clinical experience with situation songs (preunderstandings), a systematic analysis of relevant literature, followed by semi-structured interviews with three music therapists from Denmark, Austria and Germany. A flexible investigation approach was used, following hermeneutic principles......The aim of this study was to survey the various therapeutic intentions behind the use of one particular improvisation method applied in pediatric music therapy, called the situation song (from the German term “Situationslied”- Plahl & Koch-Temming, 2008, p. 180). According to Plahl & Koch......-Temming the term situation song describes an improvised song, which is sung by the therapist or/and the child and which relates to the actual occurrence and the therapeutic relationship. The presented study focuses on the therapist’s singing only. The study was conducted in stages: An elaboration of the first...

  13. Human-in-the-Loop (HITL: Probabilistic Predictive Modeling (PPM of an Aerospace Mission/Situation Outcome

    Directory of Open Access Journals (Sweden)

    Ephraim Suhir

    2014-12-01

    Full Text Available Improvements in safety in the air and in space can be achieved through better ergonomics, better work environment, and other efforts of the traditional avionic psychology that directly affect human behaviors and performance. There is also a significant potential, however, for further reduction in aerospace accidents and casualties through better understanding the role that various uncertainties play in the planner’s and operator’s worlds of work, when never-perfect human, never failure-free navigation equipment and instrumentation, never hundred-percent-predictable response of the object of control (air- or space-craft, and uncertain-and-often-harsh environments contribute jointly to the likelihood of a mishap. By employing quantifiable and measurable ways of assessing the role and significance of such uncertainties and treating a human-in-the-loop (HITL as a part, often the most crucial part, of a complex man–instrumentation–equipment–vehicle–environment system, one could improve dramatically the state-of-the-art in assuring aerospace operational safety. This can be done by predicting, quantifying and, if necessary, even specifying an adequate (low enough probability of a possible accident. Nothing and nobody is perfect, of course, and the difference between a highly reliable object, product, performance or a mission and an insufficiently reliable one is “merely” in the level of the never-zero probability of failure. Application of the probabilistic predictive modeling (PPM concept provides a natural and an effective means for reduction of vehicular casualties. When success and safety are imperative, ability to predict and quantify the outcome of an HITL related mission or a situation is a must. This is not the current practice though. The application of the PPM concept can improve therefore the state-of-the-art in understanding and accounting for the human performance in a vehicular mission or a situation. While the traditional

  14. Reidentification of Persons Using Clothing Features in Real-Life Video

    Directory of Open Access Journals (Sweden)

    Guodong Zhang

    2017-01-01

    Full Text Available Person reidentification, which aims to track people across nonoverlapping cameras, is a fundamental task in automated video processing. Moving people often appear differently when viewed from different nonoverlapping cameras because of differences in illumination, pose, and camera properties. The color histogram is a global feature of an object that can be used for identification. This histogram describes the distribution of all colors on the object. However, the use of color histograms has two disadvantages. First, colors change differently under different lighting and at different angles. Second, traditional color histograms lack spatial information. We used a perception-based color space to solve the illumination problem of traditional histograms. We also used the spatial pyramid matching (SPM model to improve the image spatial information in color histograms. Finally, we used the Gaussian mixture model (GMM to show features for person reidentification, because the main color feature of GMM is more adaptable for scene changes, and improve the stability of the retrieved results for different color spaces in various scenes. Through a series of experiments, we found the relationships of different features that impact person reidentification.

  15. Modelling of the optimal vehicle route in terrain in emergency situations using GIS data

    Science.gov (United States)

    Rybansky, M.

    2014-02-01

    Most navigation systems in transport are oriented towards the search for optimal paths (shortest or fastest), using vector GIS data. At the time of natural disasters and emergency situations is necessary to consider roads and terrain for transport. This article is focused on finding optimal routes in terrain, which contains a number of point, line and area obstacles. The most frequent point obstacles are trees in the forest. The paper analyzes the typical structure of tree stands in the forest, their characteristics in GIS databases, as well as dimensional parameters of vehicles moving in the forest. The quality of these data is a prerequisite for finding routes between point obstacles. Searching for the fastest or shortest route of the vehicle described in this article is based on the use of the relationship between the Delaunay triangulation and Voronoi graph, the application of Dijkstra's algorithm and the optimization of fractional line. The above-mentioned methods are also exploitable for searching for the shortest route of movement among line obstructions and area obstructions, such route can be apprehended as the joining of points defining impassable terrain. In such a case, the condition must be met that the distance of terminal points of joins has to be adjusted to the extent that it will be shorter than a vehicle width increased by safe margin.

  16. Exploring a Model of Situated Professional Development: Impact on Classroom Practice

    Science.gov (United States)

    Singer, Jonathan; Lotter, Christine; Feller, Robert; Gates, Harry

    2011-04-01

    A hallmark of current science education reform involves teaching through inquiry. However, the widespread use of inquiry-based instruction in many classrooms has not occurred (Roehrig and Luft in Int J Sci Educ 26:3-24, 2004; Schneider et al. in J Res Sci Teach 42:283-312, 2005). The purpose of this study was to investigate the impact of a professional development program on middle school science teachers' ability to enact inquiry-based pedagogical practices. Data were generated through evaluation of teacher practice using the Reformed Teaching Observation Protocol (RTOP) (Sawada et al. in School Sci Math 102:245-253, 2002) at three distinct junctures, before, during, and after the professional development treatment. Analysis of teacher-participant post-institute reflections was then utilized to determine the perceived role of the various institute components. Statistical significant changes in RTOP scores indicated that the teachers were able to successfully transfer the enactment of the inquiry-based practices into their classrooms. The subsequent discussion provides connection between these pedagogical changes with use of professional development strategies that provide a situated learning environment.

  17. 3D Interactions between Virtual Worlds and Real Life in an E-Learning Community

    Directory of Open Access Journals (Sweden)

    Ulrike Lucke

    2011-01-01

    Full Text Available Virtual worlds became an appealing and fascinating component of today's internet. In particular, the number of educational providers that see a potential for E-Learning in such new platforms increases. Unfortunately, most of the environments and processes implemented up to now do not exceed a virtual modelling of real-world scenarios. In particular, this paper shows that Second Life can be more than just another learning platform. A flexible and bidirectional link between the reality and the virtual world enables synchronous and seamless interaction between users and devices across both worlds. The primary advantages of this interconnection are a spatial extension of face-to-face and online learning scenarios and a closer relationship between virtual learners and the real world.

  18. Solving a real-life large-scale energy management problem

    CERN Document Server

    Godskesen, Steffen; Kjeldsen, Niels; Larsen, Rune

    2010-01-01

    This paper introduces a three-phase heuristic approach for a large-scale energy management and maintenance scheduling problem. The problem is concerned with scheduling maintenance and refueling for nuclear power plants up to five years into the future, while handling a number of scenarios for future demand and prices. The goal is to minimize the expected total production costs. The first phase of the heuristic solves a simplified constraint programming model of the problem, the second performs a local search, and the third handles overproduction in a greedy fashion. This work was initiated in the context of the ROADEF/EURO Challenge 2010, a competition organized jointly by the French Operational Research and Decision Support Society, the European Operational Research Society, and the European utility company Electricite de France. In the concluding phase of the competition our team ranked second in the junior category and sixth overall. After correcting an implementation bug in the program that was submitted ...

  19. Experimental Validation of Switching Strategy for Tracking Control with Collision Avoidance in Non-Cooperative Situation Using Toy Model Cars

    Science.gov (United States)

    Kogiso, Kiminao; Noguchi, Makoto; Hatada, Kazuyoshi; Kida, Naoki; Hirade, Naofumi; Sugimoto, Kenji

    This paper presents some experimental validation results of an already-proposed switching control method for simultaneous achievement of collision avoidance and tracking control for a vehicle in a non-cooperative situation. To validate the method, an experimental control system is made, in which the vehicle is a toy model car possible to remotely control via infrared ray and a camera is used to measure the vehicle's state. After presenting the constructed control system, the effectiveness of the method is investigated with the results obtained from the several control experiments.

  20. Situating Motivation

    Science.gov (United States)

    Nolen, Susan Bobbitt; Horn, Ilana Seidel; Ward, Christopher J.

    2015-01-01

    This article describes a situative approach to studying motivation to learn in social contexts. We begin by contrasting this perspective to more prevalent psychological approaches to the study of motivation, describing epistemological and methodological differences that have constrained conversation between theoretical groups. We elaborate on…

  1. Toward an Engineering Model for the Aerodynamic Forces Acting on Wind Turbine Blades in Quasisteady Standstill and Blade Installation Situations

    Science.gov (United States)

    Gaunaa, Mac; Heinz, Joachim; Skrzypiński, Witold

    2016-09-01

    The crossflow principle is one of the key elements used in engineering models for prediction of the aerodynamic loads on wind turbine blades in standstill or blade installation situations, where the flow direction relative to the wind turbine blade has a component in the direction of the blade span direction. In the present work, the performance of the crossflow principle is assessed on the DTU 10MW reference blade using extensive 3D CFD calculations. Analysis of the computational results shows that there is only a relatively narrow region in which the crossflow principle describes the aerodynamic loading well. In some conditions the deviation of the predicted loadings can be quite significant, having a large influence on for instance the integral aerodynamic moments around the blade centre of mass; which is very important for single blade installation applications. The main features of these deviations, however, have a systematic behaviour on all force components, which in this paper is employed to formulate the first version of an engineering correction method to the crossflow principle applicable for wind turbine blades. The new correction model improves the agreement with CFD results for the key aerodynamic loads in crossflow situations. The general validity of this model for other blade shapes should be investigated in subsequent works.

  2. A Model of Situational Willingness to Communicate (WTC) in the Study Abroad Context

    Science.gov (United States)

    Robson, Graham

    2015-01-01

    The use of structural modeling has helped to explain constructs leading to Willingness to Communicate (WTC) in L1 and L2 contexts. When WTC was conceptualized as a trait in the L1, more personality variables were used in models. When WTC moved into the realm of second language, researchers still used trait measurements to explain the construct,…

  3. Situating Power Potentials and Dynamics of Learners and Tutors within Self-Assessment Models

    Science.gov (United States)

    Taras, Maddalena

    2016-01-01

    Many twenty-first century educational discourses focus on including and empowering independent learners. Within the context of five self-assessment models, this article evaluates how these practices relate to the realities of student involvement, empowerment and voice. A proposed new classification of these self-assessment models is presented and…

  4. Event-related potential signatures of perceived and imagined emotional and food real-life photos.

    Science.gov (United States)

    Marmolejo-Ramos, Fernando; Hellemans, Kim; Comeau, Amy; Heenan, Adam; Faulkner, Andrew; Abizaid, Alfonso; D'Angiulli, Amedeo

    2015-06-01

    Although food and affective pictures share similar emotional and motivational characteristics, the relationship between the neuronal responses to these stimuli is unclear. Particularly, it is not known whether perceiving and imagining food and affective stimuli elicit similar event-related potential (ERP) patterns. In this study, two ERP correlates, the early posterior negativity (EPN) and the late positive potential (LPP) for perceived and imagined emotional and food photographs were investigated. Thirteen healthy volunteers were exposed to a set of food photos, as well as unpleasant, pleasant, and neutral photos from the International Affective Picture System. In each trial, participants were first asked to view a photo (perception condition), and then to create a visual mental image of it and to rate its vividness (imagery condition). The results showed that during perception, brain regions corresponding to sensorimotor and parietal motivational (defensive and appetitive) systems were activated to different extents, producing a graded pattern of EPN and LPP responses specific to the photo content - more prominent for unpleasant than pleasant and food content. Also, an EPN signature occurred in both conditions for unpleasant content, suggesting that, compared to food or pleasant content, unpleasant content may be attended to more intensely during perception and may be represented more distinctly during imagery. Finally, compared to LLP activation during perception, as well as imagery and perception of all other content, LPP activation was significantly reduced during imagery of unpleasant photos, suggesting inhibition of unwanted memories. Results are framed within a neurocognitive working model of embodied emotions.

  5. Real life clinic visits do not match the ideals of shared decision making.

    Science.gov (United States)

    Lipstein, Ellen A; Dodds, Cassandra M; Britto, Maria T

    2014-07-01

    To use observation to understand how decisions about higher-risk treatments, such as biologics, are made in pediatric chronic conditions. Gastroenterology and rheumatology providers who prescribe biologics were recruited. Families were recruited when they had an outpatient appointment in which treatment with biologics was likely to be discussed. Consent/assent was obtained to video the visit. Audio of the visits in which a discussion of biologics took place were transcribed and analyzed. Our coding structure was based on prior research, shared decision making (SDM) concepts, and the initial recorded visits. Coded data were analyzed using content analysis and comparison with an existing model of SDM. We recorded 21 visits that included discussions of biologics. In most visits, providers initiated the decision-making discussion. Detailed information was typically given about the provider's preferred option with less information about other options. There was minimal elicitation of preferences, treatment goals, or prior knowledge. Few parents or patients spontaneously stated their preferences or concerns. An implicit or explicit treatment recommendation was given in nearly all visits, although rarely requested. In approximately one-third of the visits, the treatment decision was never made explicit, yet steps were taken to implement the provider's preferred treatment. We observed limited use of SDM, despite previous research indicating that parents wish to collaborate in decision making. To better achieve SDM in chronic conditions, providers and families need to strive for bidirectional sharing of information and an explicit family role in decision making. Copyright © 2014 Elsevier Inc. All rights reserved.

  6. The effectiveness of ESP (Electronic Stability Program) in reducing real life accidents.

    Science.gov (United States)

    Lie, Anders; Tingvall, Claes; Krafft, Maria; Kullgren, Anders

    2004-03-01

    ESP (Electronic Stability Program) has recently been introduced onto the market in an effort to reduce the number and severity of loss-of-control automobile accidents. This reduction is expected to be particularly evident for accidents on roads with low friction (e.g., wet or icy conditions). This study aimed to evaluate the statistical effectiveness of ESP using data from accidents that occurred in Sweden during 2000 to 2002. To control for exposure, induced exposure methods were used, where ESP-sensitive to ESP-insensitive accidents and road conditions were matched in relation to cars equipped with and without ESP. Cars of similar, or in some cases identical, make and model were used to isolate the role of ESP. As predicted, the study showed a positive effect of ESP in circumstances where road surfaces have low friction. The overall effectiveness was 22.1 (+/-21) percent, while for accidents on wet roads, the effectiveness increased to 31.5 (+/-23.4) percent. On roads covered with ice and snow, the corresponding effectiveness was 38.2 (+/-26.1) percent. In addition, ESP was found to be effective for three different types of cars: small front-wheel drive; large front-wheel drive; and large rear-wheel drive.

  7. A Novel Computational Tool for Mining Real-Life Data: Application in the Metastatic Colorectal Cancer Care Setting

    Science.gov (United States)

    Siegelmann-Danieli, Nava; Farkash, Ariel; Katzir, Itzhak; Vesterman Landes, Janet; Rotem Rabinovich, Hadas; Lomnicky, Yossef; Carmeli, Boaz; Parush-Shear-Yashuv, Naama

    2016-01-01

    Background Randomized clinical trials constitute the gold-standard for evaluating new anti-cancer therapies; however, real-life data are key in complementing clinically useful information. We developed a computational tool for real-life data analysis and applied it to the metastatic colorectal cancer (mCRC) setting. This tool addressed the impact of oncology/non-oncology parameters on treatment patterns and clinical outcomes. Methods The developed tool enables extraction of any computerized information including comorbidities and use of drugs (oncological/non-oncological) per individual HMO member. The study in which we evaluated this tool was a retrospective cohort study that included Maccabi Healthcare Services members with mCRC receiving bevacizumab with fluoropyrimidines (FP), FP plus oxaliplatin (FP-O), or FP plus irinotecan (FP-I) in the first-line between 9/2006 and 12/2013. Results The analysis included 753 patients of whom 15.4% underwent subsequent metastasectomy (the Surgery group). For the entire cohort, median overall survival (OS) was 20.5 months; in the Surgery group, median duration of bevacizumab-containing therapy (DOT) pre-surgery was 6.1 months; median OS was not reached. In the Non-surgery group, median OS and DOT were 18.7 and 11.4 months, respectively; no significant OS differences were noted between FP-O and FP-I, whereas FP use was associated with shorter OS (12.3 month; p <0.002; notably, these patients were older). Patients who received both FP-O- and FP-I-based regimens achieved numerically longer OS vs. those who received only one of these regimens (22.1 [19.9–24.0] vs. 18.9 [15.5–21.9] months). Among patients assessed for wild-type KRAS and treated with subsequent anti-EGFR agent, OS was 25.4 months and 18.7 months for 124 treated vs. 37 non-treated patients (non-significant). Cox analysis (controlling for age and gender) identified several non-oncology parameters associated with poorer clinical outcomes including concurrent use of

  8. A Proficiency Based Stepwise Endovascular Curricular Training (PROSPECT) Program Enhances Operative Performance in Real Life: A Randomised Controlled Trial.

    Science.gov (United States)

    Maertens, H; Aggarwal, R; Moreels, N; Vermassen, F; Van Herzeele, I

    2017-09-01

    Healthcare evolution requires optimisation of surgical training to provide safe patient care. Operating room performance after completion of proficiency based training in vascular surgery has not been investigated. A randomised controlled trial evaluated the impact of a Proficiency based Stepwise Endovascular Curricular Training program (PROSPECT) on the acquisition of endovascular skills and the transferability of these skills to real life interventions. All subjects performed two endovascular interventions treating patients with symptomatic iliac and/or superficial femoral artery stenosis under supervision. Primary outcomes were technical performances (Global Rating Scale [GRS]; Examiner Checklist), operative metrics, and patient outcomes, adjusted for case difficulty and trainee experience. Secondary outcomes included knowledge and technical performance after 6 weeks and 3 months. Thirty-two general surgical trainees were randomised into three groups. Besides traditional training, the first group (n = 11) received e-learning and simulation training (PROSPECT), the second group (n = 10) only had access to e-learning, while controls (n = 11) did not receive supplementary training. Twenty-nine trainees (3 dropouts) performed 58 procedures. Trainees who completed PROSPECT showed superior technical performance (GRS 39.36 ± 2.05; Checklist 63.51 ± 3.18) in real life with significantly fewer supervisor takeovers compared with trainees receiving e-learning alone (GRS 28.42 ± 2.15; p = .001; Checklist 53.63 ± 3.34; p = .027) or traditional education (GRS 23.09 ± 2.18; p = .001; Checklist 38.72 ± 3.38; p = .001). Supervisors felt more confident in allowing PROSPECT trained physicians to perform basic (p = .006) and complex (p = .003) procedures. No differences were detected in procedural parameters (such as fluoroscopy time, DAP, procedure time, etc.) or complications. Proficiency levels were maintained up to 3 months. A structured

  9. Real-life effectiveness of spa therapy in rheumatic and musculoskeletal diseases: a retrospective study of 819 patients.

    Science.gov (United States)

    Karagülle, Mine; Kardeş, Sinan; Karagülle, Müfit Zeki

    2017-05-30

    The objective of this study is to determine the use and efficacy of spa therapy in patients with a wide spectrum of rheumatic and musculoskeletal diseases under real-life clinical practice circumstances. In this retrospective observational study at the Medical Ecology and Hydroclimatology Department of Istanbul Faculty of Medicine, the records of all adult patients with rheumatic and musculoskeletal diseases who were prescribed a spa therapy in various health resorts in Turkey between 2002 and 2012 were analyzed. Patients sojourned to and stayed at a health resort and followed a usual 2-week course of spa therapy. The patients were examined within a week before and after the spa therapy at the department by the physicians and outcome measures were pain intensity (visual analog scale, VAS), patient's general evaluation (VAS), physician's general evaluation (VAS), Health Assessment Questionnaire (HAQ), Lequesne's Functional Index (LFI), Western Ontario and McMaster Universities Index (WOMAC), Waddell Index (WI), Neck Pain and Disability Scale (NPDS), Shoulder Disability Questionnaire (SDQ), Fibromyalgia Impact Questionnaire (FIQ), and Beck's Depression Inventory (BDI). In total, 819 patients were included in the analysis. The diagnoses were 536 osteoarthritis; 115 fibromyalgia; 50 lumbar disc herniation; 34 cervical disc herniation; 23 nonspecific low back pain; 22 ankylosing spondylitis; 16 rheumatoid arthritis; 9 rotator cuff tendinitis; and 14 other conditions/diseases including scoliosis, stenosing flexor tenosynovitis, congenital hip dislocation in adult, Behçet's disease, de Quervain tendinopathy, psoriatic arthritis, osteoporosis, fracture rehabilitation, and diffuse idiopathic skeletal hyperostosis. Statistically significant decrease in pain scores was found in all patients except hip osteoarthritis (p = 0.063) and rheumatoid arthritis (p = 0.134) subgroups; and statistically significant improvement in function in all patients except hip osteoarthritis

  10. A Novel Computational Tool for Mining Real-Life Data: Application in the Metastatic Colorectal Cancer Care Setting.

    Directory of Open Access Journals (Sweden)

    Nava Siegelmann-Danieli

    Full Text Available Randomized clinical trials constitute the gold-standard for evaluating new anti-cancer therapies; however, real-life data are key in complementing clinically useful information. We developed a computational tool for real-life data analysis and applied it to the metastatic colorectal cancer (mCRC setting. This tool addressed the impact of oncology/non-oncology parameters on treatment patterns and clinical outcomes.The developed tool enables extraction of any computerized information including comorbidities and use of drugs (oncological/non-oncological per individual HMO member. The study in which we evaluated this tool was a retrospective cohort study that included Maccabi Healthcare Services members with mCRC receiving bevacizumab with fluoropyrimidines (FP, FP plus oxaliplatin (FP-O, or FP plus irinotecan (FP-I in the first-line between 9/2006 and 12/2013.The analysis included 753 patients of whom 15.4% underwent subsequent metastasectomy (the Surgery group. For the entire cohort, median overall survival (OS was 20.5 months; in the Surgery group, median duration of bevacizumab-containing therapy (DOT pre-surgery was 6.1 months; median OS was not reached. In the Non-surgery group, median OS and DOT were 18.7 and 11.4 months, respectively; no significant OS differences were noted between FP-O and FP-I, whereas FP use was associated with shorter OS (12.3 month; p <0.002; notably, these patients were older. Patients who received both FP-O- and FP-I-based regimens achieved numerically longer OS vs. those who received only one of these regimens (22.1 [19.9-24.0] vs. 18.9 [15.5-21.9] months. Among patients assessed for wild-type KRAS and treated with subsequent anti-EGFR agent, OS was 25.4 months and 18.7 months for 124 treated vs. 37 non-treated patients (non-significant. Cox analysis (controlling for age and gender identified several non-oncology parameters associated with poorer clinical outcomes including concurrent use of diuretics and proton

  11. Rapid SAR and GPS Measurements and Models for Hazard Science and Situational Awareness

    Science.gov (United States)

    Owen, S. E.; Yun, S. H.; Hua, H.; Agram, P. S.; Liu, Z.; Moore, A. W.; Rosen, P. A.; Simons, M.; Webb, F.; Linick, J.; Fielding, E. J.; Lundgren, P.; Sacco, G. F.; Polet, J.; Manipon, G.

    2016-12-01

    The Advanced Rapid Imaging and Analysis (ARIA) project for Natural Hazards is focused on rapidly generating higher level geodetic imaging products and placing them in the hands of the solid earth science and local, national, and international natural hazard communities by providing science product generation, exploration, and delivery capabilities at an operational level. Space-based geodetic measurement techniques such as Interferometric Synthetic Aperture Radar (InSAR), Differential Global Positioning System (DGPS), SAR-based change detection, and image pixel tracking have recently become critical additions to our toolset for understanding and mapping the damage caused by earthquakes, volcanic eruptions, landslides, and floods. Analyses of these data sets are still largely handcrafted following each event and are not generated rapidly and reliably enough for response to natural disasters or for timely analysis of large data sets. The ARIA project, a joint venture co-sponsored by California Institute of Technology (Caltech) and by NASA through the Jet Propulsion Laboratory (JPL), has been capturing the knowledge applied to these responses and building it into an automated infrastructure to generate imaging products in near real-time that can improve situational awareness for disaster response. In addition, the ARIA project is developing the capabilities to provide automated imaging and analysis capabilities necessary to keep up with the imminent increase in raw data from geodetic imaging missions planned for launch by NASA, as well as international space agencies. We will present the progress we have made on automating the analysis of SAR data for hazard monitoring and response using data from Sentinel 1a/b as well as continuous GPS stations. Since the beginning of our project, our team has imaged events and generated response products for events around the world. These response products have enabled many conversations with those in the disaster response community

  12. Situative Creativity

    OpenAIRE

    2013-01-01

    Creativity is crucial for the success of any company. IT support has been shown to foster creative processes, but still disregards characteristics that are typical for creative situations, such as the need for social, intuitive and face-to-face interaction. This thesis investigates requirements via interviews and explores and evaluates a novel concept for IT driven creativity support, based on a multi-touch tabletop display and coupled private mobile devices. Obwohl der Einsatz von IT erf...

  13. Group Practices and Partnerships: A traditional model that Fits Many Situations.

    Science.gov (United States)

    Pickering, Stephen R

    2015-01-01

    The traditional group practice model can take many forms, including general practitioners, specialists, and combinations, as well as solo practitioners sharing space and staff, partnerships, and other legal entities. These practices may share some or all staff functions, including contracting for some functions. The essential characteristic is that those treating patients also have full control over and often direct management of the business aspects of the practice. The most important requirements for success in this model may be a common philosophy of patient care and mutual trust regarding business matters.

  14. Evolution of a predictive internal model in an embodied and situated agent.

    Science.gov (United States)

    Gigliotta, Onofrio; Pezzulo, Giovanni; Nolfi, Stefano; Nolfi, Sefano

    2011-12-01

    We show how simulated robots evolved for the ability to display a context-dependent periodic behavior can spontaneously develop an internal model and rely on it to fulfill their task when sensory stimulation is temporarily unavailable. The analysis of some of the best evolved agents indicates that their internal model operates by anticipating sensory stimuli. More precisely, it anticipates functional properties of the next sensory state rather than the exact state that sensors will assume. The characteristics of the states that are anticipated and of the sensorimotor rules that determine how the agents react to the experienced states, however, ensure that they produce very similar behaviour during normal and blind phases in which sensory stimulation is available or is self-generated by the agent, respectively. Agents' internal models also ensure an effective transition during the phases in which agents' internal dynamics is decoupled and re-coupled with the sensorimotor flow. Our results suggest that internal models might have arisen for behavioral reasons and successively exapted for other cognitive functions. Moreover, the obtained results suggest that self-generated internal states should not necessarily match in detail the corresponding sensory states and might rather encode more abstract and motor-oriented information.

  15. Teacher Educators' In-Action Mental Models in Different Teaching Situations

    Science.gov (United States)

    Mevorach, Miriam; Strauss, Sidney

    2012-01-01

    In previous studies on teachers' cognition, we discovered that teachers' teaching can be described via a general in-action mental model (IAMM) concerning the structure of the mind and the roles of teaching in fostering children's learning. The purpose of our study was to examine teacher educators' IAMM regarding student teachers' minds and…

  16. Making it stick : Exploring the effects of information and behavioral training on self-protectiveness of citizens in a real-life safety setting

    NARCIS (Netherlands)

    Kievik, M.; Misana-Ter Huurne, E. F.J.; Gutteling, J. M.; Giebels, E.

    2018-01-01

    This study contributes to our knowledge of whether and why citizens engage in self-protective behavior with regard to a real-life risk (the transportation of chemical substances by train). We assume that the way in which relevant risk information is processed, actively vs. passively, is a crucial

  17. Translation of a tailored nutrition and resistance exercise intervention for elderly people to a real-life setting: adaptation process and pilot study

    NARCIS (Netherlands)

    Dongen, van E.J.I.; Leerlooijer, J.N.; Steijns, J.M.; Tieland, C.A.B.; Groot, de C.P.G.M.; Haveman-Nies, A.

    2017-01-01

    Background
    Combining increased dietary protein intake and resistance exercise training for elderly people is a promising strategy to prevent or counteract the loss of muscle mass and decrease the risk of disabilities. Using findings from controlled interventions in a real-life setting requires a

  18. Making it stick : Exploring the effects of information and behavioral training on self-protectiveness of citizens in a real-life safety setting

    NARCIS (Netherlands)

    Kievik, M.; Misana-Ter Huurne, E. F.J.; Gutteling, J. M.; Giebels, E.

    2018-01-01

    This study contributes to our knowledge of whether and why citizens engage in self-protective behavior with regard to a real-life risk (the transportation of chemical substances by train). We assume that the way in which relevant risk information is processed, actively vs. passively, is a crucial fa

  19. Son, you’re smoking on Facebook! College students’ disclosures on social networking sites as indicators of real-life risk behaviors

    NARCIS (Netherlands)

    Hoof, van Joris J.; Bekkers, Jeroen; Vuuren, van Mark

    2014-01-01

    Health risk behavior in student populations is an issue of major concern, and students’ risk levels are difficult to determine. In this study, we explore the extent to which information disclosed publicly on Facebook provides reliable indications of five real-life health behaviors. Questionnaire da

  20. Son, you’re smoking on Facebook! College students’ disclosures on social networking sites as indicators of real-life risk behaviors

    NARCIS (Netherlands)

    van Hoof, Joris Jasper; Bekkers, Jeroen; van Vuuren, Hubrecht A.

    2014-01-01

    Health risk behavior in student populations is an issue of major concern, and students’ risk levels are difficult to determine. In this study, we explore the extent to which information disclosed publicly on Facebook provides reliable indications of five real-life health behaviors. Questionnaire

  1. The application of equilibrium models to incidence situations using the example of the exposure pathway human milk

    Energy Technology Data Exchange (ETDEWEB)

    Steiner, Martin; Karcher, Klaus; Nosske, Dietmar [Bundesamt fuer Strahlenschutz, Oberschleissheim (Germany)

    2012-06-15

    The radiation exposure after a short-term release of radioactive substances is often calculated assuming equilibrium conditions. An example is that of the German Incident Calculation Bases for nuclear power plants with pressurized water reactors. Here, the contamination of human milk is calculated using transfer factors. Applying this equilibrium model to incident situations raises the question whether baby's radiation exposure is adequately assessed. This contribution shows that compliance with the relevant dose limits of paragraph 49 of the German Radiation Protection Ordinance is ensured for design basis accidents on the assumption that the hypothetical breastfeeding period starts at the beginning of the activity release. Comparative analyses were performed against the biokinetic models applied by ICRP for radiation protection purposes, taking the reference nuclides {sup 137}Cs, {sup 90}Sr, {sup 131}I, {sup 241}Am and long-lived plutonium isotopes as examples. (orig.)

  2. Innovation through Wearable Sensors to Collect Real-Life Data among Pediatric Patients with Cardiometabolic Risk Factors

    Directory of Open Access Journals (Sweden)

    Kestens Yan

    2014-01-01

    Full Text Available Background. While increasing evidence links environments to health behavior, clinicians lack information about patients’ physical activity levels and lifestyle environments. We present mobile health tools to collect and use spatio-behavioural lifestyle data for personalized physical activity plans in clinical settings. Methods. The Dyn@mo lifestyle intervention was developed at the Sainte-Justine University Hospital Center to promote physical activity and reduce sedentary time among children with cardiometabolic risk factors. Mobility, physical activity, and heart rate were measured in free-living environments during seven days. Algorithms processed data to generate spatio-behavioural indicators that fed a web-based interactive mapping application for personalised counseling. Proof of concept and tools are presented using data collected among the first 37 participants recruited in 2011. Results. Valid accelerometer data was available for 5.6 (SD=1.62 days in average, heart rate data for 6.5 days, and GPS data was available for 6.1 (2.1 days. Spatio-behavioural indicators were shared between patients, parents, and practitioners to support counseling. Conclusion. Use of wearable sensors along with data treatment algorithms and visualisation tools allow to better measure and describe real-life environments, mobility, physical activity, and physiological responses. Increased specificity in lifestyle interventions opens new avenues for remote patient monitoring and intervention.

  3. Innovation through Wearable Sensors to Collect Real-Life Data among Pediatric Patients with Cardiometabolic Risk Factors.

    Science.gov (United States)

    Yan, Kestens; Tracie, Barnett; Marie-Ève, Mathieu; Mélanie, Henderson; Jean-Luc, Bigras; Benoit, Thierry; St-Onge, Maxime; Marie, Lambert

    2014-01-01

    Background. While increasing evidence links environments to health behavior, clinicians lack information about patients' physical activity levels and lifestyle environments. We present mobile health tools to collect and use spatio-behavioural lifestyle data for personalized physical activity plans in clinical settings. Methods. The Dyn@mo lifestyle intervention was developed at the Sainte-Justine University Hospital Center to promote physical activity and reduce sedentary time among children with cardiometabolic risk factors. Mobility, physical activity, and heart rate were measured in free-living environments during seven days. Algorithms processed data to generate spatio-behavioural indicators that fed a web-based interactive mapping application for personalised counseling. Proof of concept and tools are presented using data collected among the first 37 participants recruited in 2011. Results. Valid accelerometer data was available for 5.6 (SD = 1.62) days in average, heart rate data for 6.5 days, and GPS data was available for 6.1 (2.1) days. Spatio-behavioural indicators were shared between patients, parents, and practitioners to support counseling. Conclusion. Use of wearable sensors along with data treatment algorithms and visualisation tools allow to better measure and describe real-life environments, mobility, physical activity, and physiological responses. Increased specificity in lifestyle interventions opens new avenues for remote patient monitoring and intervention.

  4. Investigation of uranium isotopic signatures in real-life particles from a nuclear facility by thermal ionization mass spectrometry.

    Science.gov (United States)

    Kraiem, Monia; Richter, Stephan; Kühn, Heinz; Stefaniak, Elzbieta A; Kerckhove, Giovani; Truyens, Jan; Aregbe, Yetunde

    2011-04-15

    An improved method was recently developed for the isotopic analysis of single-reference uranium oxide particles for nuclear safeguards. This method is a combination of analytical tools including in situ SEM micromanipulation, filament carburization and multiple ion counting (MIC) detection, which is found to improve sensitivity for thermal ionization mass spectrometry (TIMS) isotope ratio analysis. The question was raised whether this method could be applied for the detection of nuclear signatures in real-life particles with unknown isotopic composition. Therefore, environmental dust was collected in different locations within a nuclear facility. The screening of the samples to find the uranium particles of interest was performed using a scanning electron microscope (SEM) equipped with an energy-dispersive X-ray (EDX) detector. The comparison of the measurement results to reference data evaluated by international safeguards authorities was of key importance for data interpretation. For the majority of investigated particles, detection of uranium isotopic signatures provided information on current and past nuclear feed operations that compared well with facility declarations.

  5. Modifying social anxiety related to a real-life stressor using online Cognitive Bias Modification for interpretation.

    Science.gov (United States)

    Hoppitt, Laura; Illingworth, Josephine L; MacLeod, Colin; Hampshire, Adam; Dunn, Barnaby D; Mackintosh, Bundy

    2014-01-01

    Modifying threat related biases in attention and interpretation has been shown to successfully reduce global symptoms of anxiety in high anxious and clinically anxious samples (termed Cognitive Bias Modification, CBM). However, the possibility that CBM can be used as a way to prevent anxiety associated with an upcoming real-life stressful event in vulnerable populations has yet to be systematically examined. The present study aimed to assess whether a two-week course of online CBM for interpretations (CBM-I) could reduce social evaluative fear when starting university. Sixty-nine students anxious about starting university completed five sessions of online CBM in the two weeks prior to starting university, or completed a placebo control intervention. Results indicated that CBM-I reduced social evaluative fear from baseline to day one of starting university to a greater extent than the placebo control intervention. Also, there was a greater reduction in state anxiety and a trend indicating a greater reduction in social evaluative fear in the CBM-I group at 4 weeks follow-up. Results suggest that CBM-I could be used as a preventative tool to help reduce anxiety specific to challenging life events.

  6. A case study on variability management in software product lines: identifying why real-life projects fail

    Directory of Open Access Journals (Sweden)

    Tom Huysegoms

    2013-01-01

    Full Text Available Economies of scale can be seen as some kind of “holy grail” in state of the art literature on the development of sets of related software systems. Software product line methods are often mentioned in this context, due to the variability management aspects they propose, in order to deal with sets of related software systems. They realize the sought-after reusability. Both variability management and software product lines already have a strong presence in theoretical research, but in real-life software product line projects trying to obtain economies of scale still tend to fall short of target. The objective of this paper is to study this gap between theory and reality through a case study in order to see why such gap exists, and to find a way to bridge this gap. Through analysis of the causes of failure identified by the stakeholders in the case study, the underlying problem, which is found to be located in the requirements engineering phase, is crystallized. The identification of a framework describing the problems will provide practitioners with a better focus for future endeavors in the field of software product lines, so that economies of scale can be achieved.

  7. Is it time for studying real-life debiasing? Evaluation of the effectiveness of an analogical intervention technique

    Directory of Open Access Journals (Sweden)

    Balazs eAczel

    2015-08-01

    Full Text Available The aim of this study was to initiate the exploration of debiasing methods applicable in real-life settings for achieving lasting improvement in decision-making competence regarding multiple decision biases. Here, we tested the potentials of the analogical encoding method for decision debiasing. The advantage of this method is that it can foster the transfer from learning abstract principles to improving behavioral performance. For the purpose of the study, we devised an analogical debiasing technique for ten biases (covariation detection, insensitivity to sample size, base rate neglect, regression to the mean, outcome bias, sunk cost fallacy, framing effect, anchoring bias, overconfidence bias, planning fallacy and assessed the susceptibility of the participants (N = 154 to these biases before and four weeks after the training. We also compared the effect of the analogical training to the effect of an ‘awareness training’ and a ‘no-training’ control group. Results suggested improved performance of the analogical training group only on tasks where the violations of statistical principles are measured. The interpretation of these findings require further investigation, yet it is possible that analogical training may be the most effective in the case of learning abstract concepts, such as statistical principles, which are otherwise difficult to master. The study encourages a systematic research of debiasing trainings and the development of intervention assessment methods to measure the endurance of behavior change in decision debiasing.

  8. 'Naked-eye' detection of biologically important anions in aqueous media by colorimetric receptor and its real life applications

    Science.gov (United States)

    Singh, Archana; Trivedi, Darshak R.

    2017-05-01

    A colorimetric receptor R 2-[(2-Hydroxy-naphthalen-1-ylmethylene)-hydrazonomethyl]-quinolin-8-ol has been designed and synthesized with good yield and characterized by the standard spectroscopic techniques such as FT-IR, UV-Visible, 1H NMR, 13C NMR and ESI-MS. The receptor R showed naked-eye detection and spectral change in the presence of F-, AcO- and H2PO4- over other anions. Interestingly, receptor R displaying high selective recognition towards F-, AcO- ion with a drastic color change from pale yellow to red in dry DMSO solvent and orange in mixed solvent DMSO/H2O (9:1, v/v). The behavior of receptor R towards F-, AcO- ion was investigated using UV-Vis and 1H NMR experiment. The detailed 1H NMR experiment result revealed that the receptor R is forming the hydrogen bonding between imine nitrogen and phenolic sbnd OH proton towards anions. The receptor R is able to detect sodium salts of flouride (NaF) and acetate (NaAcO) in aqueous medium and it exhibited dramatic color change from pale yellow to red. The receptor R demonstrated itself to be useful for real life application by detecting flouride and acetate ion in sea-water and commercially available product such as toothpaste, mouthwash and vinegar solution.

  9. Can long-term dentine bonding created in real life be forecasted by parameters established in the laboratory?

    Science.gov (United States)

    Rêgo, Heleine M. C.; Alves, Thaís S.; Bresciani, Eduardo; Niu, Li-na; Tay, Franklin R.; Pucci, César R.

    2016-01-01

    Tooth-coloured plastic dental fillings secured by adhesives to tooth structures are widely used to fix decayed teeth. Whereas laboratory tests demonstrate rapid deterioration of the ability of the adhesives to stick to dentine, clinical studies show that these fillings are relatively durable. This discrepancy suggests that the parameters used for simulating bond degradation in the laboratory setting do not correlate well with clinical outcomes. The present study examined the long-term tensile bond strength of resin composite fillings performed in real life and under different laboratory-simulated bonding conditions to identify parameters that may be used to forecast the durability of adhesive bonds created in dentine. Fillings placed in vivo were subjected to different periods of intraoral function. In vitro specimens were bonded based on whether simulated pulpal pressure (SPP) or thermomechanical cycling was implemented, and how long the completed fillings were stored in water. Thermomechanical cycling used in combination with long-term water ageing are useful in forecasting the decline in strength of resin-dentine bonds created in vivo. These parameters should be adopted for future evaluations. Conversely, the use of SPP does not appear to be a significant parameter in the simulation of long-term clinical deterioration of bond integrity. PMID:27886272

  10. Loneliness and the social monitoring system: Emotion recognition and eye gaze in a real-life conversation.

    Science.gov (United States)

    Lodder, Gerine M A; Scholte, Ron H J; Goossens, Luc; Engels, Rutger C M E; Verhagen, Maaike

    2016-02-01

    Based on the belongingness regulation theory (Gardner et al., 2005, Pers. Soc. Psychol. Bull., 31, 1549), this study focuses on the relationship between loneliness and social monitoring. Specifically, we examined whether loneliness relates to performance on three emotion recognition tasks and whether lonely individuals show increased gazing towards their conversation partner's faces in a real-life conversation. Study 1 examined 170 college students (Mage = 19.26; SD = 1.21) who completed an emotion recognition task with dynamic stimuli (morph task) and a micro(-emotion) expression recognition task. Study 2 examined 130 college students (Mage = 19.33; SD = 2.00) who completed the Reading the Mind in the Eyes Test and who had a conversation with an unfamiliar peer while their gaze direction was videotaped. In both studies, loneliness was measured using the UCLA Loneliness Scale version 3 (Russell, 1996, J. Pers. Assess., 66, 20). The results showed that loneliness was unrelated to emotion recognition on all emotion recognition tasks, but that it was related to increased gaze towards their conversation partner's faces. Implications for the belongingness regulation system of lonely individuals are discussed.

  11. Real Life Firewall

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Beijing has been working to ensure fire safety during the Olympic Games is of the highest level "We’ve drawn on the safety experiences of the Sydney and Athens Olympic Games,and endeavor to build reliable Olympic fire protection sys- tems to ensure that we can reach the goal of a safe Olympics,"said Li Jin,Vice Director of the Beijing Fire Bureau. Fire might seem an unlikely problem at an Olympic event,but in fact it has posed a threat before.At the opening of the 25th Barcelona Olympic Games,the hotel where the former President of the International Olympic Committee(IOC),Samaranch

  12. Story and Real Life

    Directory of Open Access Journals (Sweden)

    Robert P. Waxler

    2013-06-01

    Full Text Available Why should we be concerned about the fate of literature as we move from a book culture to a screen culture in the digital age? Not primarily because we are losing our sense of story, but because we are losing our sense of the central importance of linguistic narrative. There is a difference. The technologies creating the digital revolution seem to devalue language and increasingly to do away with boundaries, celebrating instead speed and boundless exhilaration. The visual trumps the linguistic, the image and the screen trump the word and the book. As a result, we no longer seem to engage deeply with others or ourselves. We are beginning to move, in other words, from “a reading brain” to “a digital brain,” from a brain capable of deep reading and deep thinking to a brain increasingly addled by spectacle and surface sensation. We are losing our standing as “linguistic beings.”

  13. Story and Real Life

    Directory of Open Access Journals (Sweden)

    Robert P. Waxler

    2013-06-01

    Full Text Available Why should we be concerned about the fate of literature as we move from a book culture to a screen culture in the digital age? Not primarily because we are losing our sense of story, but because we are losing our sense of the central importance of linguistic narrative. There is a difference. The technologies creating the digital revolution seem to devalue language and increasingly to do away with boundaries, celebrating instead speed and boundless exhilaration. The visual trumps the linguistic, the image and the screen trump the word and the book. As a result, we no longer seem to engage deeply with others or ourselves. We are beginning to move, in other words, from “a reading brain” to “a digital brain,” from a brain capable of deep reading and deep thinking to a brain increasingly addled by spectacle and surface sensation. We are losing our standing as “linguistic beings.”

  14. Modeling the Impact of Value of Information on Situational Awareness using C3TRACE

    Science.gov (United States)

    2016-05-01

    Hanratty et al. detail the approaches for elicitation of expertise from intelligence analysts at the US Army Research Laboratory (ARL) and for the...simulation and human performance model known as Command, Control, and Communications – Techniques for Reliable Assessment of Concept Execution (C3TRACE...mission-relevant findings to the commander by the end of the day. The preparation and delivery of the presentation requires 2 h, thus the analyst only

  15. Dynamics of satellite motion and situational modeling in the INTERSHOCK project

    Energy Technology Data Exchange (ETDEWEB)

    Boyarskii, M.N.; Pavlov, V.P.; Prokhorenko, V.I.; Smirnov, V.N.; Zastenker, G.N.

    1986-09-01

    Several problems in the ballistic support for the INTERSHOCK experiment are discussed: selection of the optimal satellite orbit, the modeling of its crossings of the earth bow shock, and the analysis of the satellite's motion about its center of mass. Results are given from a determination of the earth bow shock after 6-month orbiting of the Prognoz-10-Interkosmos satellite (April-November, 1985).

  16. Does Playing Sports Video Games Predict Increased Involvement in Real-Life Sports Over Several Years Among Older Adolescents and Emerging Adults?

    Science.gov (United States)

    Adachi, Paul J C; Willoughby, Teena

    2016-02-01

    Given the extreme popularity of video games among older adolescents and emerging adults, the investigation of positive outcomes of video game play during these developmental periods is crucial. An important direction for research in this area is the investigation of a link between sports video game play and involvement in real-life sports among youth. Yet, this association has not been examined in the long-term among older adolescents and emerging adults, and thus represents an exciting new area for discovery. The primary goal of the current study, therefore, was to examine the long-term association between sports video game play and involvement in real-life sports clubs among older adolescents and emerging adults. In addition, we examined whether self-esteem was an underlying mechanism of this longitudinal association. We surveyed older adolescents and emerging adults (N = 1132; 70.6 % female; M age = 19.06 years, range of 17-25 years at the first assessment) annually over 3 years about their video game play, self-esteem, and involvement in real-life sports. We found a long-term predictive effect of sports video game play on increased involvement in real-life sports over the 3 years. Furthermore, we demonstrated that self-esteem was an underlying mechanism of this long-term association. Our findings make an important contribution to an emerging body of literature on the positive outcomes of video game play, as they suggest that sports video game play may be an effective tool to promote real-life sports participation and physical activity among older adolescents and emerging adults.

  17. Experimentally fitted biodynamic models for pedestrian-structure interaction in walking situations

    Science.gov (United States)

    Toso, Marcelo André; Gomes, Herbert Martins; da Silva, Felipe Tavares; Pimentel, Roberto Leal

    2016-05-01

    The interaction between moving humans and structures usually occurs in slender structures in which the level of vibration is potentially high. Furthermore, there is the addition of mass to the structural system due to the presence of people and an increase in damping due to the human body´s ability to absorb vibrational energy. In this paper, a test campaign is presented to obtain parameters for a single degree of freedom (SDOF) biodynamic model that represents the action of a walking pedestrian in the vertical direction. The parameters of this model are the mass (m), damping (c) and stiffness (k). The measurements were performed on a force platform, and the inputs were the spectral acceleration amplitudes of the first three harmonics at the waist level of the test subjects and the corresponding amplitudes of the first three harmonics of the vertical ground reaction force. This leads to a system of nonlinear equations that is solved using a gradient-based optimization algorithm. A set of individuals took part in the tests to ensure inter-subject variability, and, regression expressions and an artificial neural network (ANN) were used to relate the biodynamic parameters to the pacing rate and the body mass of the pedestrians. The results showed some scatter in damping and stiffness that could not be precisely correlated with the masses and pacing rates of the subjects. The use of the ANN resulted in significant improvements in the parameter expressions with a low uncertainty. Finally, the measured vertical accelerations on a prototype footbridge show the adequacy of the numerical model for the representation of the effects of walking pedestrians on a structure. The results are consistent for many crowd densities.

  18. Integral modeling and financial impact of the geothermal situation and power plant at Soultz-sous-Forêts

    Science.gov (United States)

    Heidinger, Philipp

    2010-07-01

    The science about deep Enhanced Geothermal Systems (EGS) is still an emerging process and for further spreading economics is the key of the technology. To understand the financial situation, a program for economic evaluation was developed. This software (Euronaut) is completely modularized and considers all cash flows. Projects like an EGS are wrapped into tree-like structures. Based on the results which were gained at Soultz-sous-Forêts, two configurations were designed. The first EGS configuration consists of a simplified two well (doublet) system where the dependencies of all components (mainly the reservoir, wells, pumps and the heat-to-power conversion unit) are physically and economically linked together. The realization of these dependencies and their complex interactions enable a sensitivity analysis of the borehole depth and reservoir depth, respectively. As a result, depth dependent effective costs and revenues of an EGS plant with the geohydrological characteristics of Soultz-sous-Forêts are determined. As a future development, the second configuration will adapt the actual situation at Soultz-sous-Forêts with the individual features of all four wells (GPK1 - GPK4). Then, this model can be used for all kinds of sensitivity analyses to clarify the impact of certain components or to optimize the operation scheme; e.g. the flow rates.

  19. How the Economic and Financial Situation of the Community Affects Sport Clubs’ Resources: Evidence from Multi-Level Models

    Directory of Open Access Journals (Sweden)

    Pamela Wicker

    2015-02-01

    Full Text Available In many Western countries, local community sport clubs are important providers of leisure, sport, and social programs. These sport clubs are nonprofit organizations, which operate in an increasingly challenging environment. This study considers a club’s direct local environment, i.e., the community the club is located in. The open systems model and the resource dependence represent the theoretical framework. The purpose of this research is to examine the effect of the financial and economic environment in the community on the resource situation of sport clubs (human, infrastructure, and financial resources. The empirical evaluation is undertaken using data from a nationwide survey of non-profit sport clubs in Germany (organizational level; n = 19,345, which are combined with secondary data on community characteristics (community level; n = 3153. Given the hierarchical data structure, multi-level analyses are applied. The results show that volunteer problems are smaller among clubs in communities with high unemployment. Facility and financial problems are greater in large communities. Sport clubs located in communities that could break even were also more likely to break even themselves. The findings show that resource problems are not necessarily due to poor club management, since higher-level (community factors significantly affect the resource situation of sport clubs too.

  20. Deep situationality

    DEFF Research Database (Denmark)

    Matejskova, Tatiana

    2014-01-01

    This article seeks to extend scholarship rethinking insiderness in qualitative research through an examination of the shifting terrain of the constitution of insides in an ethnographic research on everyday politics of integration and belonging in eastern Berlin. I reflect here on my experiences...... as a Slovak national with immigration experi- ence, a nominal outsider to both the country of research, Germany, and its immigrant subjects, the post-Soviet Russian-speaking migrants. Focusing on the production of time-spaces of proximity as a deeply situational process, I stress in particular the un...

  1. Early mortality in multiple myeloma: the time-dependent impact of comorbidity: A population-based study in 621 real-life patients.

    Science.gov (United States)

    Ríos-Tamayo, Rafael; Sáinz, Juan; Martínez-López, Joaquín; Puerta, José Manuel; Chang, Daysi-Yoe-Ling; Rodríguez, Teresa; Garrido, Pilar; de Veas, José Luís García; Romero, Antonio; Moratalla, Lucía; López-Fernández, Elisa; González, Pedro Antonio; Sánchez, María José; Jiménez-Moleón, José Juan; Jurado, Manuel; Lahuerta, Juan José

    2016-07-01

    Multiple myeloma is a heterogeneous disease with variable survival; this variability cannot be fully explained by the current systems of risk stratification. Early mortality remains a serious obstacle to further improve the trend toward increased survival demonstrated in recent years. However, the definition of early mortality is not standardized yet. Importantly, no study has focused on the impact of comorbidity on early mortality in multiple myeloma to date. Therefore, we analyzed the role of baseline comorbidity in a large population-based cohort of 621 real-life myeloma patients over a 31-year period. To evaluate early mortality, a sequential multivariate regression model at 2, 6, and 12 months from diagnosis was performed. It was demonstrated that comorbidity had an independent impact on early mortality, which is differential and time-dependent. Besides renal failure, respiratory disease at 2 months, liver disease at 6 months, and hepatitis virus C infection at 12 months, were, respectively, associated with early mortality, adjusting for other well-established prognostic factors. On the other hand, the long-term monitoring in our study points out a modest downward trend in early mortality over time. This is the first single institution population-based study aiming to assess the impact of comorbidity on early mortality in multiple myeloma. It is suggested that early mortality should be analyzed at three key time points (2, 6, and 12 months), in order to allow comparisons between studies. Comorbidity plays a critical role in the outcome of myeloma patients in terms of early mortality. Am. J. Hematol. 91:700-704, 2016. © 2016 Wiley Periodicals, Inc.

  2. A deliberative framework to identify the need for real-life evidence building of new cancer drugs after interim funding decision.

    Science.gov (United States)

    Leung, Leanne; de Lemos, Mário L; Kovacic, Laurel

    2017-01-01

    Background With the rising cost of new oncology treatments, it is no longer sustainable to base initial drug funding decisions primarily on prospective clinical trials as their performance in real-life populations are often difficult to determine. In British Columbia, an approach in evidence building is to retrospectively analyse patient outcomes using observational research on an ad hoc basis. Methods The deliberative framework was constructed in three stages: framework design, framework validation and treatment programme characterization, and key informant interview. Framework design was informed through a literature review and analyses of provincial and national decision-making processes. Treatment programmes funded between 2010 and 2013 were used for framework validation. A selection concordance rate of 80% amongst three reviewers was considered to be a validation of the framework. Key informant interviews were conducted to determine the utility of this deliberative framework. Results A multi-domain deliberative framework with 15 assessment parameters was developed. A selection concordance rate of 84.2% was achieved for content validation of the framework. Nine treatment programmes from five different tumour groups were selected for retrospective outcomes analysis. Five contributory factors to funding uncertainties were identified. Key informants agreed that the framework is a comprehensive tool that targets the key areas involved in the funding decision-making process. Conclusions The oncology-based deliberative framework can be routinely used to assess treatment programmes from the major tumour sites for retrospective outcomes analysis. Key informants indicate this is a value-added tool and will provide insight to the current prospective funding model.

  3. River water quality modelling under drought situations - the Turia River case

    Science.gov (United States)

    Paredes-Arquiola, Javier; Macián, Javier; Pedro-Monzonís, María; Belda, Edgar; Momblanch, Andrea; Andreu, Joaquín

    2016-10-01

    Drought and water shortage effects are normally exacerbated due to collateral impacts on water quality, since low streamflow affects water quality in rivers and water uses depend on it. One of the most common problems during drought conditions is maintaining a good water quality while securing the water supply to demands. This research analyses the case of the Turia River Water Resource System located in Eastern Spain. Its main water demand comes as urban demand from Valencia City, which intake is located in the final stretch of the river, where streamflow may become very low during droughts. As a result, during drought conditions concentrations of pathogens and other contaminants increase, compromising the water supply to Valencia City. In order to define possible solutions for the above-mentioned problem, we have developed an integrated model for simulating water management and water quality in the Turia River Basin to propose solutions for water quality problems under water scarcity. For this purpose, the Decision Support System Shell AQUATOOL has been used. The results demonstrate the importance of applying environmental flows as a measure of reducing pollutant's concentration depending on the evolution of a drought event and the state of the water resources system.

  4. River water quality modelling under drought situations – the Turia River case

    Directory of Open Access Journals (Sweden)

    J. Paredes-Arquiola

    2016-10-01

    Full Text Available Drought and water shortage effects are normally exacerbated due to collateral impacts on water quality, since low streamflow affects water quality in rivers and water uses depend on it. One of the most common problems during drought conditions is maintaining a good water quality while securing the water supply to demands. This research analyses the case of the Turia River Water Resource System located in Eastern Spain. Its main water demand comes as urban demand from Valencia City, which intake is located in the final stretch of the river, where streamflow may become very low during droughts. As a result, during drought conditions concentrations of pathogens and other contaminants increase, compromising the water supply to Valencia City. In order to define possible solutions for the above-mentioned problem, we have developed an integrated model for simulating water management and water quality in the Turia River Basin to propose solutions for water quality problems under water scarcity. For this purpose, the Decision Support System Shell AQUATOOL has been used. The results demonstrate the importance of applying environmental flows as a measure of reducing pollutant's concentration depending on the evolution of a drought event and the state of the water resources system.

  5. The cardiovascular perfusionist as a model for the successful technologist in high stress situations.

    Science.gov (United States)

    Friday, P J; Mook, W J

    1991-01-01

    This study investigates the psychological profiles of highly stressed medical technologists. One hundred and four individuals representing a cross-section of the United States who function as operators of heart-lung machines during open heart surgery (perfusionists) were studied using both internal and external models based on the works of Eric Berne and Karen Horney. Daily exposure to life and death responsibilities combined with the constant pressures of maintaining current technical skills can make the profession selected for this study representative of high technology professions that require a great deal of coping. Results of this study indicate that there is a balanced psychological profile in successful technologists functioning in long-term, high-stressed occupations. Female perfusionists appear to be more aggressive and critical than their male counterparts. This is seen as an attempt by female perfusionists to compensate for what has historically been a male dominanted, highly technical and high-stressed occupation. Generalizations for candidate selections to high stressed occupations could be made as well as projections of foundations for possible progressive disillusionment (burn out).

  6. Internet addiction prevalence and quality of (real) life: a meta-analysis of 31 nations across seven world regions.

    Science.gov (United States)

    Cheng, Cecilia; Li, Angel Yee-lam

    2014-12-01

    Internet addiction (IA) has emerged as a universal issue, but its international estimates vary vastly. This multinational meta-analysis fills this gap by providing estimates of its global prevalence. Two hypotheses were formulated to explain the cross-national variations. The accessibility hypothesis predicts that IA prevalence is positively related to Internet penetration rate and GDP per capita, whereas the quality of (real) life hypothesis predicts that IA prevalence is inversely related to a global national index of life satisfaction and specific national indices of environmental quality. Multiple search strategies were used in an attempt to retrieve all empirical reports from 1996 to 2012 that adopted the Young Diagnostic Questionnaire or Internet Addiction Test for assessing generalized IA. The data set comprised 164 prevalence figures derived from 80 reports, including 89,281 participants from 31 nations across seven world regions. A random effects meta-analysis showed a global prevalence estimate of 6.0% [95% CI 5.1-6.9], with moderate heterogeneity (I(2)=44%, p<0.0001). The highest prevalence was in the Middle East with 10.9% [95% CI 5.4-16.3], and the lowest was in Northern and Western Europe with 2.6% [95% CI 1.0-4.1]. Moreover, IA prevalence was higher for nations with greater traffic time consumption, pollution, and dissatisfaction with life in general. The prevalence rate of IA varies across world regions. IA prevalence is inversely associated with the quality of life, as reflected by both subjective (life satisfaction) and objective (quality of environmental conditions) indicators.

  7. Internet Addiction Prevalence and Quality of (Real) Life: A Meta-Analysis of 31 Nations Across Seven World Regions

    Science.gov (United States)

    Li, Angel Yee-lam

    2014-01-01

    Abstract Internet addiction (IA) has emerged as a universal issue, but its international estimates vary vastly. This multinational meta-analysis fills this gap by providing estimates of its global prevalence. Two hypotheses were formulated to explain the cross-national variations. The accessibility hypothesis predicts that IA prevalence is positively related to Internet penetration rate and GDP per capita, whereas the quality of (real) life hypothesis predicts that IA prevalence is inversely related to a global national index of life satisfaction and specific national indices of environmental quality. Multiple search strategies were used in an attempt to retrieve all empirical reports from 1996 to 2012 that adopted the Young Diagnostic Questionnaire or Internet Addiction Test for assessing generalized IA. The data set comprised 164 prevalence figures derived from 80 reports, including 89,281 participants from 31 nations across seven world regions. A random effects meta-analysis showed a global prevalence estimate of 6.0% [95% CI 5.1–6.9], with moderate heterogeneity (I2=44%, p<0.0001). The highest prevalence was in the Middle East with 10.9% [95% CI 5.4–16.3], and the lowest was in Northern and Western Europe with 2.6% [95% CI 1.0–4.1]. Moreover, IA prevalence was higher for nations with greater traffic time consumption, pollution, and dissatisfaction with life in general. The prevalence rate of IA varies across world regions. IA prevalence is inversely associated with the quality of life, as reflected by both subjective (life satisfaction) and objective (quality of environmental conditions) indicators. PMID:25489876

  8. Acute social stress before the planning phase improves memory performance in a complex real life-related prospective memory task.

    Science.gov (United States)

    Glienke, Katharina; Piefke, Martina

    2016-09-01

    Successful execution of intentions, but also the failure to recall are common phenomena in everyday life. The planning, retention, and realization of intentions are often framed as the scientific concept of prospective memory. The current study aimed to examine the influence of acute stress on key dimensions of complex "real life" prospective memory. To this end, we applied a prospective memory task that involved the planning, retention, and performance of intentions during a fictional holiday week. Forty healthy males participated in the study. Half of the subjects were stressed with the Socially Evaluated Cold Pressor Test (SECPT) before the planning of intentions, and the other half of the participants underwent a control procedure at the same time. Salivary cortisol was used to measure the effectiveness of the SECPT stress induction. Stressed participants did not differ from controls in planning accuracy. However, when we compared stressed participants with controls during prospective memory retrieval, we found statistically significant differences in PM across the performance phase. Participants treated with the SECPT procedure before the planning phase showed improved prospective memory retrieval over time, while performance of controls declined. Particularly, there was a significant difference between the stress and control group for the last two days of the holiday week. Interestingly, control participants showed significantly better performance for early than later learned items, which could be an indicator of a primacy effect. This differential effect of stress on performance was also found in time- and event-dependent prospective memory. Our results demonstrate for the first time, that acute stress induced before the planning phase may improve prospective memory over the time course of the performance phase in time- and event-dependent prospective memory. Our data thus indicate that prospective memory can be enhanced by acute stress.

  9. Towards elucidating the neuronal basis of cognitive units in non-experimental, real-life communication using ECoG

    Directory of Open Access Journals (Sweden)

    Johanna eDerix

    2014-06-01

    Full Text Available Exchange of thoughts by means of expressive speech is fundamental to human communication. However, the neuronal basis of real-life communication in general, and of verbal exchange of ideas in particular, has rarely been studied until now. Here, our aim was to establish an approach for exploring the neuronal processes related to cognitive idea units (IUs in conditions of non-experimental speech production. We investigated whether such units corresponding to single, coherent chunks of speech with syntactically-defined borders, are useful to unravel the neuronal mechanisms underlying real-world human cognition. To this aim, we employed simultaneous electrocorticography (ECoG and video recordings obtained in pre-neurosurgical diagnostics of epilepsy patients. We transcribed non-experimental, daily hospital conversations, identified IUs in transcriptions of the patients’ speech, classified the obtained IUs according to a previously-proposed taxonomy focusing on memory content, and investigated the underlying neuronal activity. In each of our three subjects, we were able to collect a large number of IUs which could be assigned to different functional IU subclasses with a high inter-rater agreement. IU-related responses of brain activity showed significant modulations of the spectral magnitude in high gamma frequencies (70-150 Hz in mouth motor, language, and higher-order association areas. Neuronal responses specific to different IU subclasses were observed in the inferior parietal and prefrontal cortex. Thus, IU-based analysis of ECoG recordings during non-experimental communication elicited topographically- and functionally-specific effects. We conclude that segmentation of spontaneous real-world speech in linguistically-motivated units is a promising strategy for elucidating the neuronal basis of mental processing during non-experimental communication.

  10. Use and performance of non-invasive ventilation in Internal Medicine ward: a real-life study

    Directory of Open Access Journals (Sweden)

    Francesco Ventrella

    2015-01-01

    Full Text Available Controlled trials demonstrated efficacy and safety of non-invasive ventilation (NIV in treatment of acute respiratory failure, initially in Intensive Care Units, then in other care settings (semi-intensive care units, emergency departments, and also in the wards, more often pneumological ones. Few studies have been published about NIV in Italian wards of Internal Medicine with full self-management of NIV by internists in a normal ward setting. We performed a prospective real-life study about the use of NIV in Internal Medicine ward devoid of a critical area of semi-intensive therapy, with the aim of confirming, in this setting, the effectiveness of NIV. During a period of 13 months, 42 patients with hypercapnic respiratory failure of different etiology and acidosis (pH<7.25were treated by NIV. NIV was successful in 81% of patients. In-hospital mortality was 9.5%. Safety of NIV is demonstrated by the absence of serious complications: only 7 patients showed poor compliance and 2 patients had facial pressure ulcer due to the mask. There were not statistical differences in success rate of NIV according to severity of acidosis at admission (pH<7.25 vs pH>7.25, neither according to the acute physiology and chronic health evaluation II score and the national early warning score, but the modified early warning score only showed statistically significant difference with lower values in the success group: 2.82±1.57 vs 4.13±1.46 (P<0.05. NIV has proven to be effective and safe in Internal Medicine ward.

  11. Treatment Efficacy and Safety of Tenofovir-Based Therapy in Chronic Hepatitis B: A Real Life Cohort Study in Korea

    Science.gov (United States)

    Ahn, Hyo Jun; Song, Myeong Jun; Jang, Jeong Won; Bae, Si Hyun; Choi, Jong Young; Yoon, Seung Kew

    2017-01-01

    Background & Aims We evaluated the efficacy and safety of Tenofovir disoproxil fumarate (TDF)-based therapy in naïve and treatment-experienced chronic hepatitis B (CHB) patients for 96 weeks in Korean real life practice. Methods A total of 209 CHB patients with a prescription for TDF at the Seoul and Daejeon St. Mary’s hospitals were enrolled from December 2012 to October 2014. We compared the virological responses and evaluated the renal safety of treatment-naive and treatment-experienced patients. Results An overall complete virological response (CVR) was achieved in 80.4% and 84.6% of patients at weeks 48 and 96, respectively. In a subgroup analysis, CVR at week 96 was present in 88.4%, 75.0%, 75.5%, and 83.3% of participants in the lamivudine-resistant (LAM-R) group, adefovir-resistant (ADV-R) group, multidrug-resistant (MDR) group, and suboptimal response group, respectively. In a multivariate analysis, ADV-R, MDR, hepatitis B virus DNA, and hepatitis B e antigen were independent predictors for CVR. With regard to renal safety, diabetes mellitus, cirrhosis, and an initial low estimated glomerular filtration rate were independent factors affecting creatinine elevation (≥0.5 mg/dL). Moreover, two patients with DM and cirrhosis experienced TDF-related Fanconi syndrome. Conclusions TDF-based therapy demonstrated sustained viral suppression and favorable safety during a 2-year treatment period. The LAM-R and suboptimal response groups showed comparable efficacy to the naïve group, while the ADV-R and MDR groups were significantly associated with a low CVR. Close monitoring of renal safety should be mandatory when treating CHB patients receiving TDF, particularly those with DM and cirrhosis. PMID:28114428

  12. Differential influence of the 5-HTTLPR genotype, neuroticism and real-life acute stress exposure on appetite and energy intake.

    Science.gov (United States)

    Capello, Aimée E M; Markus, C Rob

    2014-06-01

    Stress or negative mood often promotes energy intake and overeating. Since the serotonin transporter-linked polymorphic region (5-HTTLPR) is found to mediate stress vulnerability as well as to influence energy intake, this gene may also influence the negative effects of stress exposure on overeating. Moreover, since stress proneness also reflects cognitive stress vulnerability - as often defined by trait neuroticism - this may additionally predispose for stress-induced overeating. In the present study it was investigated whether the 5-HTTLPR genotype interacted with neuroticism on changes in mood, appetite and energy intake following exposure to a real-life academic examination stressor. In a balanced-experimental design, homozygous S-allele and L-allele carriers (N = 94) with the lowest and highest neuroticism scores were selected from a large database of 5-HTTLPR genotyped students. Mood, appetite and energy intake were measured before and after a 2-hour academic examination and compared with a control day. Examination influenced appetite for particular sweet snacks differently depending on 5-HTTLPR genotype and neuroticism. S/S compared with L/L subjects reported greater examination stress, and this was accompanied by a more profound post-stress increase in appetite for sweet snacks. Data also revealed a 5-HTTLPR genotype by trait neuroticism interaction on energy intake, regardless of examination. These results consolidate previous assumptions of 5-HTTLPR involvement in stress vulnerability and suggest 5-HTTLPR and neuroticism may influence stress-induced overeating depending on the type of food available. These findings furthermore link previous findings of increased risk for weight gain in S/S-allele carriers, particularly with high scores on trait neuroticism, to increased energy intake.

  13. Laboratory alcohol self-administration experiments do not increase subsequent real-life drinking in young adult social drinkers.

    Science.gov (United States)

    Sommer, Christian; Seipt, Christian; Spreer, Maik; Blümke, Toni; Markovic, Alexandra; Jünger, Elisabeth; Plawecki, Martin H; Zimmermann, Ulrich S

    2015-06-01

    While the utility of experimental free-access alcohol self-administration paradigms is well established, little data exist addressing the question of whether study participation influences subsequent natural alcohol consumption. We here present drinking reports of young adults before and after participation in intravenous alcohol self-administration studies. Timeline Follow-back drinking reports for the 6 weeks immediately preceding the first, and the 6 weeks after the last experimental alcohol challenge were examined from subjects completing 1 of 2 similar alcohol self-administration paradigms. In study 1, 18 social drinkers (9 females, mean age 24.1 years) participated in 3 alcohol self-infusion sessions up to a maximum blood alcohol concentration (BAC) of 160 mg%. Study 2 involved 60 participants (30 females, mean age 18.3 years) of the Dresden Longitudinal Study on Alcohol Use in Young Adults (D-LAYA), who participated in 2 sessions of alcohol self-infusion up to a maximum BAC of 120 mg%, and a nonexposed age-matched control group of 42 (28 females, mean age 18.4 years) subjects. In study 1, participants reported (3.7%) fewer heavy drinking days as well as a decrease of 2.5 drinks per drinking day after study participation compared to prestudy levels (p alcohol-exposed participants reported 7.1% and non-alcohol-exposed controls 6.5% fewer drinking days at poststudy measurement (p alcohol self-administration experiments does not increase subsequent real-life drinking of young adults. Copyright © 2015 by the Research Society on Alcoholism.

  14. Relationship between eating behaviours and food and drink consumption in healthy postmenopausal women in a real-life context.

    Science.gov (United States)

    Goulet, Julie; Provencher, Véronique; Piché, Marie-Eve; Lapointe, Annie; John Weisnagel, S; Nadeau, André; Bergeron, Jean; Lemieux, Simone

    2008-10-01

    Associations between eating behaviours and dietary variables have not been thoroughly investigated in healthy postmenopausal women in a real life uncontrolled context. To investigate how eating behaviours (cognitive dietary restraint, disinhibition and susceptibility to hunger) were associated with food and drink consumption, energy density and meal pattern in 112 healthy postmenopausal women (age 56.8 (SD 4.4) years) not on.hormonal therapy. Women completed a 3 d weighed food record and filled out the Three-Factor Eating Questionnaire. The sample was divided according to the median of the distribution of cognitive dietary restraint and disinhibition (9 and 6 respectively). Both subgroups of women with high restraint level (presenting either high or low disinhibition) consumed a diet with a lower energy density than subgroups of women with lower restraint level. Women with high restraint-low disinhibition had a lower consumption of red meat and processed meat and a lower consumption of diet soft drinks than women with low restraint-high disinhibition. They were also characterised by a higher intake of whole grains than women with high restraint-high disinhibition and than women with lower restraint level (with either high or low disinhibition). Women with high restraint-high disinhibition levels showed differences in dietary variables when compared with subgroups of women with lower restraint level, namely for refined grains and diet soft drinks. We conclude that in healthy postmenopausal women, dietary consumption of specific food and drink may be related to particular eating behaviours. Women with high restraint and low disinhibition levels generally showed the most healthy dietary pattern.

  15. Treatment satisfaction of patients undergoing ranibizumab therapy for neovascular age-related macular degeneration in a real-life setting

    Directory of Open Access Journals (Sweden)

    Gohil R

    2016-05-01

    Full Text Available Rishma Gohil,1,2 Roxanne Crosby-Nwaobi,1,2 Angus Forbes,2 Ben J Burton,3 Philip Hykin,1 Sobha Sivaprasad1,4 1National Institute for Health Research Moorfields Biomedical Research Centre, London, 2Diabetes Nursing, King’s College London, London, 3Ophthalmology Department, James Paget University Hospital, Great Yarmouth, 4Laser and Retinal Research Unit, King’s College Hospital, London, UK Context: Treatment satisfaction with a loading phase of monthly injections for 3 months followed by a pro-re-nata regimen of ranibizumab in neovascular age-related macular degeneration (nAMD remains unclear.Aims: The aim was to evaluate the treatment satisfaction of persons with nAMD treated with ranibizumab in a real-life setting.Settings and design: A cross-sectional study was conducted across three eye clinics within the National Health Service in the UK, where treatment is provided free at point of contact.Materials and methods: A total of 250 patients were selected randomly for the study. Treatment satisfaction was assessed using the Macular Treatment Satisfaction Questionnaire. Data were collected on satisfaction of the service provided (Client Service Questionnaire-8 and the patients’ demographic and quality of life and treatment history. Factors governing treatment questionnaire were determined.Results: The most important factors that determined the satisfaction were the service provided at the clinic (Client Service Questionnaire-8, health-related quality of life (EQ-5D-3L, and duration of AMD. Visual acuity changes were rated as less important than one would have expected.Conclusion: The study result suggested that treatment satisfaction for nAMD was governed by the perception of being reviewed and injected regularly over a long period of time than the actual change in visual acuity from the treatment. Keyword: macular treatment satisfaction questionnaire, patient related outcome measure, treatment history, quality of life 

  16. Role model and prototype matching: Upper-secondary school students’ meetings with tertiary STEM students

    DEFF Research Database (Denmark)

    Lykkegaard, Eva; Ulriksen, Lars

    2016-01-01

    -secondary school students from university-distant backgrounds during and after their participation in an 18-months long university-based recruitment and outreach project involving tertiary STEM students as role models. The analysis focusses on how the students’ meetings with the role models affected their thoughts...... concerning STEM students and attending university. The regular self-to-prototype matching process was shown in real-life role-models meetings to be extended to a more complex three-way matching process between students’ self-perceptions, prototype images and situation-specific conceptions of role models...

  17. Parameter estimation of social forces in pedestrian dynamics models via a probabilistic method.

    Science.gov (United States)

    Corbetta, Alessandro; Muntean, Adrian; Vafayi, Kiamars

    2015-04-01

    Focusing on a specific crowd dynamics situation, including real life experiments and measurements, our paper targets a twofold aim: (1) we present a Bayesian probabilistic method to estimate the value and the uncertainty (in the form of a probability density function) of parameters in crowd dynamic models from the experimental data; and (2) we introduce a fitness measure for the models to classify a couple of model structures (forces) according to their fitness to the experimental data, preparing the stage for a more general model-selection and validation strategy inspired by probabilistic data analysis. Finally, we review the essential aspects of our experimental setup and measurement technique.

  18. SMART-ER: A Situation Model of Anticipated Response consequences in Tactical decisions in skill acquisition —Extended and Revised

    Directory of Open Access Journals (Sweden)

    Markus eRaab

    2015-01-01

    Full Text Available SMART (Situation Model of Anticipated Response consequences in tactical decisions describes the interaction of top-down and bottom-up processes in skill acquisition and thus the dynamic interaction of sensory and motor capacities in embodied cognition. The empirically validated, extended, and revised SMART-ER can now predict when specific dynamic interactions of top-down and bottom-up processes have a beneficial or detrimental effect on performance and learning depending on situational constraints. The model is empirically supported and proposes learning strategies for when situation complexity varies or time pressure is present. Experiments from expertise research in sports illustrate that neither bottom-up nor top-down processes are bad or good per se but their effects depend on personal and situational characteristics.

  19. An improved model of alliances between political parties

    CERN Document Server

    Bagarello, Fabio

    2016-01-01

    We consider an operatorial model of alliances between three political parties which interact with their electors, with the undecided voters, and with the electors of the other parties. This extends what was done in a previous paper, where this last type of interactions was not considered. Of course, taking them into account makes the system closer to real life. To produce an exactly solvable model, we restrict here to quadratic Hamiltonians, so that the equations of motion turn out to be linear. The dynamics of the so-called {\\em decision functions} are deduced, and some explicit situations are considered in details.

  20. The fragrance hand immersion study - an experimental model simulating real-life exposure for allergic contact dermatitis on the hands

    DEFF Research Database (Denmark)

    Heydorn, S; Menné, T; Andersen, Klaus Ejner

    2003-01-01

    Recently, we showed that 10 x 2% of consecutively patch-tested hand eczema patients had a positive patch test to a selection of fragrances containing fragrances relevant to hand exposure. In this study, we used repeated skin exposure to a patch test-positive fragrance allergen in patients...... previously diagnosed with hand eczema to explore whether immersion of fingers in a solution with or without the patch-test-positive fragrance allergen would cause or exacerbate hand eczema on the exposed finger. The study was double blinded and randomized. All participants had a positive patch test to either...... hydroxycitronellal or Lyral (hydroxyisohexyl 3-cyclohexene carboxaldehyde). Each participant immersed a finger from each hand, once a day, in a solution containing the fragrance allergen or placebo. During the first 2 weeks, the concentration of fragrance allergen in the solution was low (approximately 10 p...

  1. Endocrine effects of real-life mixtures of persistent organic pollutants (POP) in experimental models and wild fish.

    Science.gov (United States)

    Berg, Vidar; Kraugerud, Marianne; Nourizadeh-Lillabadi, Rasoul; Olsvik, Pål A; Skåre, Janneche U; Alestrøm, Peter; Ropstad, Erik; Zimmer, Karin Elisabeth; Lyche, Jan L

    2016-01-01

    A series of studies have assessed the occurrence, levels, and potential adverse effects of persistent organic pollutants (POP) in fish from Lake Mjøsa. In this lake, high levels of various POP were detected in biota. Fish from the nearby Lake Losna contain background levels of POP and served as reference (controls) in these studies. Significantly higher prevalence of mycobacteriosis and pathological changes were documented in burbot (Lota lota) from Mjøsa compared to burbot from Losna. Further, transcriptional profiling identified changes in gene expression in burbot from Mjøsa compared to burbot from Losna associated with drug metabolism enzymes and oxidative stress. POP extracted from burbot liver oil from the two lakes was used to expose zebrafish (Danio rerio) during two consecutive generations. During both generations, POP mixtures from both lakes increased the rate of mortality, induced earlier onset of puberty, and skewed sex ratio toward males. However, opposite effects on weight gain were found in exposure groups compared to controls during the two generations. Exposure to POP from both lakes was associated with suppression of ovarian follicle development. Analyses of genome-wide transcription profiling identified functional networks of genes associated with weight homeostasis, steroid hormone functions, and insulin signaling. In human cell studies using adrenocortical H295R and primary porcine theca and granulosa cells, exposure to lake extracts from both populations modulated steroid hormone production with significant difference from controls. The results suggest that POP from both lakes may possess the potential to induce endocrine disruption and may adversely affect health in wild fish.

  2. Bacteriotherapy with Streptococcus salivarius 24SMB and Streptococcus oralis 89a nasal spray for preventing recurrent acute otitis media in children: a real-life clinical experience.

    Science.gov (United States)

    La Mantia, Ignazio; Varricchio, Attilio; Ciprandi, Giorgio

    2017-01-01

    Recurrence of acute otitis media (RAOM) is a relevant issue in the clinical practice. "Bacteriotherapy" has been proposed as an option in children with RAOM. Streptococcus salivarius 24SMB nasal spray has been previously demonstrated to reduce the risk of acute otitis media (AOM) in otitis-prone children. The current retrospective and observational study aimed to confirm this outcome in a real-life setting, such as the common pediatric practice. Group A (108 children) served as control; group B (159 children) was treated with S. salivarius 24SMB and Streptococcus oralis 89a nasal spray after the first AOM episode. Active treatment consisted of 3 monthly courses: 2 puffs per nostril twice/day for a week. Group B showed a significant reduction of AOM episodes in comparison with group A (psalivarius 24SMB and S. oralis 89a nasal spray could be effective in the prevention of RAOM in a real-life setting.

  3. Rationale and design of the PREDICE project: cost-effectiveness of type 2 diabetes prevention among high-risk Spanish individuals following lifestyle intervention in real-life primary care setting

    Directory of Open Access Journals (Sweden)

    Bolíbar Bonaventura

    2011-08-01

    Full Text Available Abstract Background Type 2 diabetes is an important preventable disease and a growing public health problem. Based on information provided by clinical trials, we know that Type 2 diabetes can be prevented or delayed by lifestyle intervention. In view of translating the findings of diabetes prevention research into real-life it is necessary to carry out community-based evaluations so as to learn about the feasibility and effectiveness of locally designed and implemented programmes. The aim of this project was to assess the effectiveness of an active real-life primary care strategy in high-risk individuals for developing diabetes, and then evaluate its efficiency. Methods/Design Cost-Effectiveness analysis of the DE-PLAN (Diabetes in Europe - Prevention using Lifestyle, physical Activity and Nutritional intervention project when applied to a Mediterranean population in Catalonia (DE-PLAN-CAT. Multicenter, longitudinal cohort assessment (4 years conducted in 18 primary health-care centres (Catalan Health Institute. Individuals without diabetes aged 45-75 years were screened using the Finnish Diabetes Risk Score - FINDRISC - questionnaire and a 2-h oral glucose tolerance test. All high risk tested individuals were invited to participate in either a usual care intervention (information on diet and cardiovascular health without individualized programme, or the intensive DE-PLAN educational program (individualized or group periodically reinforced. Oral glucose tolerance test was repeated yearly to determine diabetes incidence. Besides measuring the accumulated incidence of diabetes, information was collected on economic impact of the interventions in both cohorts (using direct and indirect cost questionnaires and information on utility measures (Quality Adjusted Life Years. A cost-utility and a cost-effectiveness analysis will be performed and data will be modelled to predict long-term cost-effectiveness. Discussion The project was intended to evidence

  4. Evaluating some indicators for identifying mountain waves situations in snow days by means of numerical modeling and continuous data

    Science.gov (United States)

    Sanchez, Jose Luis; Posada, Rafael; Hierro, Rodrigo; García-Ortega, Eduardo; Lopez, Laura; Gascón, Estibaliz

    2013-04-01

    Madrid - Barajas airport is placed at 70 km away from the Central System and snow days and mountains waves are considered as risks days for landing operations. This motivated the study of mesoscale factors affecting this type of situations. The availability of observational data gathered during three consecutives winter campaigns in the Central System along with data from high-resolution numerical models, have allowed the evaluation of the environmental conditions necessary for mountain waves formations in snow days and were characterized from observational data and numerical simulations. By means of Meteosat Second Generation satellite images, lee clouds were observed in 25 days corresponding to the 2008-2011 winter seasons. Six of them, which also presented NW low level flow over the mountain range, were analyzed. Necessary conditions for oscillations as well as vertical wave propagation were studied from radiometer data and MM5 model simulations. From radiometer data the presence of stable environment in the six selected events is confirmed. From MM5 model, dynamic conditions allowing the flow to cross the mountain range were evaluated in three different locations around the mountain range. Simulations of vertical velocity show that MM5 model is able to detect mountain waves. The waves present in the six selected events are examined. Tropospheric were able to forecast energy release associated with the mountain waves. The vertical wavelength presented a high variability due to intense background winds at high tropospheric levels. The average values estimated for λz were between 3 and 12 km. The intrinsic period estimated was around 30 and 12 km. The simulations were able to forecast energy release associated with mountain waves. Acknowledgments: This study was supported by the Plan Nacional de I+D of Spain, through the grants CGL2010-15930, Micrometeo IPT-310000-2010-022 and the Junta de Castilla y León through the grant LE220A11-2.

  5. Time-Frequency Feature Representation Using Multi-Resolution Texture Analysis and Acoustic Activity Detector for Real-Life Speech Emotion Recognition

    Directory of Open Access Journals (Sweden)

    Kun-Ching Wang

    2015-01-01

    Full Text Available The classification of emotional speech is mostly considered in speech-related research on human-computer interaction (HCI. In this paper, the purpose is to present a novel feature extraction based on multi-resolutions texture image information (MRTII. The MRTII feature set is derived from multi-resolution texture analysis for characterization and classification of different emotions in a speech signal. The motivation is that we have to consider emotions have different intensity values in different frequency bands. In terms of human visual perceptual, the texture property on multi-resolution of emotional speech spectrogram should be a good feature set for emotion classification in speech. Furthermore, the multi-resolution analysis on texture can give a clearer discrimination between each emotion than uniform-resolution analysis on texture. In order to provide high accuracy of emotional discrimination especially in real-life, an acoustic activity detection (AAD algorithm must be applied into the MRTII-based feature extraction. Considering the presence of many blended emotions in real life, in this paper make use of two corpora of naturally-occurring dialogs recorded in real-life call centers. Compared with the traditional Mel-scale Frequency Cepstral Coefficients (MFCC and the state-of-the-art features, the MRTII features also can improve the correct classification rates of proposed systems among different language databases. Experimental results show that the proposed MRTII-based feature information inspired by human visual perception of the spectrogram image can provide significant classification for real-life emotional recognition in speech.

  6. Safety of new DAAs for chronic HCV infection in a real life experience: role of a surveillance network based on clinician and hospital pharmacist

    OpenAIRE

    Nappi, A.; Perrella, A; Bellopede, P.; Lanza, A.; Izzi, A.; Spatarella, M.; Sbreglia, C

    2017-01-01

    Background Direct Antiviral Agents (DAAs) for HCV therapy represents a step ahead in the cure of chronic hepatitis C. Notwithstanding the promising results in several clinical trials, few data are available on adverse effects in real life settings. Methods We have evaluated 170 patients with persistent infection and on those eligible to treatment we have followed up them through a network managed by clinician and hospital pharmacist. Results According to our data we have found that 41% (32 ou...

  7. Efficacy and safety of low-dose anticholinergics to treat men with lower urinary tract symptoms with overactive bladder: a retrospective study based on real life practice

    OpenAIRE

    Park, Kyung Kgi; Lee, Seung Hwan; Chung, Byung Ha; Kim, Su Jin; Kwak, Cheol; Son, Hwan Cheol; Kim, Sae Woong; Lee, Ji Youl

    2013-01-01

    Purpose: To investigate whether combination treatment using an ?-blocker and 2 mg of tolterodine could improve the International Prostate Symptom Score (IPSS) as much as ?-blocker and 4 mg of tolterodine without voiding difficulties in real life practice. Methods: We restrospectively recruited patients who were treated at four urology clinics between January 2006 and May 2008. A total of 1,094 men with lower urinary tract symptoms/overactive bladder (LUTS/OAB) were assigned to one of three gr...

  8. A Multi-Class Proportional Myocontrol Algorithm for Upper Limb Prosthesis Control: Validation in Real-Life Scenarios on Amputees.

    Science.gov (United States)

    Amsuess, Sebastian; Goebel, Peter; Graimann, Bernhard; Farina, Dario

    2015-09-01

    conclusion, the method proposed and validated in real-life use scenarios, allows the practical usability of multifunctional hand prostheses in an intuitive way, with significant advantages with respect to previous systems.

  9. Menu-engineering in restaurants - adapting portion sizes on plates to enhance vegetable consumption: a real-life experiment.

    Science.gov (United States)

    Reinders, Machiel J; Huitink, Marlijn; Dijkstra, S Coosje; Maaskant, Anna J; Heijnen, Joris

    2017-12-25

    The aim of this research was to investigate whether increased portion sizes of vegetables and decreased portion sizes of meat on main dishes increased the amount of vegetables consumed in a real-life restaurant setting without affecting customer satisfaction. The participants were unaware of the experiment. A cross-over design was used in which three restaurants were randomly assigned to a sequence of an intervention and control condition. In the intervention period, the vegetable portion sizes on the plates of main dishes were doubled (150 g of vegetables instead of 75 g) and the portion sizes of meat on the plates were reduced by an average of 12.5%. In the control period, the portion sizes of the main dishes were maintained as usual. In total, 1006 observations and questionnaires were included. Vegetable consumption from plates was significantly higher during the intervention period (M = 115.5 g) than during the control period (M = 61.7 g). Similarly, total vegetable consumption (including side dishes) was significantly higher during the intervention period (M = 178.0 g) than during the control period (M = 137.0 g). Conversely, meat consumption was significantly lower during the intervention period (M = 183.1 g) than during the control period (M = 211.1 g). Satisfaction with the restaurant visit did not differ between the intervention period (M = 1.27) and control period (M = 1.35). Satisfaction with the main dish was significantly lower during the intervention period (M = 1.25) than during the control period (M = 1.38), although in both cases, the scores indicated that participants remained (very) satisfied with their main dish. This study showed that increasing vegetable portions in combination with decreasing meat portions (unknowingly to the consumer) increased the amount of vegetables consumed and decreased the amount of meat consumed. Furthermore, despite the changes in portion sizes, participants remained satisfied

  10. Characteristics and outcome of patients with primary CNS lymphoma in a "real-life" setting compared to a clinical trial.

    Science.gov (United States)

    Zeremski, Vanja; Koehler, Michael; Fischer, Thomas; Schalk, Enrico

    2016-04-01

    We aimed to compare the characteristics and outcome of patients treated within the multi-centre German Primary CNS Lymphoma Study Group 1 trial (G-PCNSL-SG-1; TRIAL group) and patients treated outside this clinical trial ("real-life" setting, R-LIFE group). Therefore, we conducted a retrospective single-centre study in order to analyse all patients with newly diagnosed primary CNS lymphoma (PCNSL) treated consecutively in our institution between November 2000 and June 2015. Altogether, 86 patients were analysed (median 68 years). Twenty patients were treated within (TRIAL) and 66 patients outside the clinical trial (R-LIFE), respectively. The majority (n = 75; 87 %) received high-dose methotrexate as the first-line treatment. Thirty-eight of 66 patients (57.6 %) responded to the first-line therapy. The R-LIFE patients were older (median age 70 vs. 62 years; p = 0.005) and had more frequently a worse performance status (ECOG score 2-4: 59.1 vs. 20.0 %; p = 0.004; median Karnofsky index 70 vs. 80 %; p = 0.003) and less frequently a low prognostic score (IELSG score 0-1: 19.7 vs. 45.0 %; p = 0.038), than the TRIAL patients. Median overall survial (OS) was shorter for the R-LIFE patients (9.3 months [95 % CI 1.9-16.7] vs. 33.4 months [95 % CI 17.6-49.2]; p = 0.065). Median progression-free survival (PFS) was significantly inferior for the R-LIFE patients (3.4 months [95 % CI 2.4-4.4] vs. 24.8 months [95 % CI 4.6-45.0]; p = 0.037). Our data indicate that the outcome of PCNSL patients treated outside, but about analogous to the G-PCNSL-SG-1 trial, was poor. This is likely explained by more unfavourable prognostic factors in patients being treated off trial.

  11. A two-year evaluation of the 'real life' impact of COPD on patients in Germany: The DACCORD observational study.

    Science.gov (United States)

    Kardos, Peter; Vogelmeier, Claus; Worth, Heinrich; Buhl, Roland; Lossi, Nadine S; Mailänder, Claudia; Criée, Carl-Peter

    2017-03-01

    DACCORD is an observational, non-interventional study being conducted in German primary and secondary care centres. The study aims to describe the impact of disease (including exacerbations) and treatments over 2 years on 'real-life' patients with chronic obstructive pulmonary disease (COPD). Patients had a clinical and spirometry diagnosis of COPD, were aged ≥40 years and, on recruitment, were initiating or changing COPD maintenance medication. The only exclusion criteria were asthma and randomised clinical trial participation. Exacerbations data were collected every 3 months. COPD medication, COPD Assessment Test (CAT) and forced expiratory volume in 1 s (FEV1) were recorded at baseline and after 1 and 2 years. A total of 6122 patients were recruited, 3137 (51.2%) of whom completed the 2-year visit. The mean age of these patients was 65.6 years, 59% were male, 69% had mild or moderate airflow limitation, and their mean COPD Assessment Test (CAT) total score was 20.3. Overall, there was a trend towards decreasing COPD exacerbation rates over the 2-year follow-up period, with rates of 0.390 during Year 1 and 0.347 during Year 2. Rates were lower in patients with no exacerbation during the 6 months prior to entry (0.263 and 0.251 during Years 1 and 2, respectively), with 51.6% of patients having no exacerbation during the 6 months prior to entry and over the 2-year follow-up. Approximately 50% of the overall population experienced a clinically relevant improvement from baseline in CAT total score at Year 1 and 2. When assessed by treatment class (or classes), persistence to medication was high (77.8% in Year 1 and 71.4% in Year 2). Overall, the 2-year follow-up data from DACCORD suggest that for most patients with COPD exacerbations are a rare event. For the majority of patients, the focus should be on managing symptoms, and the impact that these symptoms have on their daily lives. Even for those patients who do exacerbate, although prevention of exacerbations is

  12. Temporal condensation and dynamic λ-transition within the complex network: an application to real-life market evolution

    Science.gov (United States)

    Wiliński, Mateusz; Szewczak, Bartłomiej; Gubiec, Tomasz; Kutner, Ryszard; Struzik, Zbigniew R.

    2015-02-01

    We fill a void in merging empirical and phenomenological characterisation of the dynamical phase transitions in complex networks by identifying and thoroughly characterising a triple sequence of such transitions on a real-life financial market. We extract and interpret the empirical, numerical, and analytical evidences for the existence of these dynamical phase transitions, by considering the medium size Frankfurt stock exchange (FSE), as a typical example of a financial market. By using the canonical object for the graph theory, i.e. the minimal spanning tree (MST) network, we observe: (i) the (initial) dynamical phase transition from equilibrium to non-equilibrium nucleation phase of the MST network, occurring at some critical time. Coalescence of edges on the FSE's transient leader (defined by its largest degree) is observed within the nucleation phase; (ii) subsequent acceleration of the process of nucleation and the emergence of the condensation phase (the second dynamical phase transition), forming a logarithmically diverging temporal λ-peak of the leader's degree at the second critical time; (iii) the third dynamical fragmentation phase transition (after passing the second critical time), where the λ-peak logarithmically relaxes over three quarters of the year, resulting in a few loosely connected sub-graphs. This λ-peak (comparable to that of the specific heat vs. temperature forming during the equilibrium continuous phase transition from the normal fluid I 4He to the superfluid II 4He) is considered as a prominent result of a non-equilibrium superstar-like superhub or a dragon-king's abrupt evolution over about two and a half year of market evolution. We capture and meticulously characterise a remarkable phenomenon in which a peripheral company becomes progressively promoted to become the dragon-king strongly dominating the complex network over an exceptionally long period of time containing the crash. Detailed analysis of the complete trio of the

  13. SAROTA: application of specific absorption rate (SAR) and over-the-air (OTA) data for the characterization of the real-life exposure due to mobile phones

    Science.gov (United States)

    Monebhurrun, Vikass

    2013-04-01

    The RF exposure level of a mobile phone is quantified by the measurement of the specific absorption rate (SAR) under laboratory conditions. The SAR which is measured while the mobile phone is operated at maximum power level does not reflect the real-life exposure scenario since the mobile phone typically re-adjusts its power level and frequency depending on the quality of the communication link with the nearest base station. The choice of a low RF exposure device based on the comparison of the relative SAR values of mobile phones can be misleading. The real-life RF exposure also depends on the over-the-air (OTA) performance of the mobile phone. Taken independently, the two sets of data do not allow a straightforward comparison of the global RF performance amongst mobile phones. A unique and simple parameter denoted as the SAROTA index is proposed for the characterization of mobile phones with regard to both RF exposure and OTA performance. The SAROTA index provides the real-life exposure index of the mobile phone.

  14. Management of bipolar disorder in the intercontinental region: an international, multicenter, non-interventional, cross-sectional study in real-life conditions

    Science.gov (United States)

    Samalin, Ludovic; Vieta, Eduard; Okasha, Tarek Ahmed; Uddin, MM. Jalal; Ahmadi Abhari, Seyed Ali; Nacef, Fethi; Mishyiev, Vyacheslav; Aizenberg, Dovi; Ratner, Yaël; Melas-Melt, Lydie; Sedeki, Idir; Llorca, Pierre Michel

    2016-01-01

    Most of the existing data on real-life management of bipolar disorder are from studies conducted in western countries (mostly United States and Europe). This multinational, observational cohort study aimed to describe the management and clinical outcomes of bipolar patients in real-life conditions across various intercontinental countries (Bangladesh, Egypt, Iran, Israel, Tunisia, and Ukraine). Data on socio-demographic and disease characteristics, current symptomatology, and pharmacological treatment were collected. Comparisons between groups were performed using standard statistical tests. Overall, 1180 patients were included. The median time from initial diagnosis was 80 months. Major depressive disorder was the most common initial diagnosis. Mood stabilizers and antipsychotics were the most common drugs being prescribed at the time of the study. Antidepressants (mainly selective serotonin uptake inhibitors [SSRIs]) were administered to 36.1% of patients. Patients with bipolar I disorder received higher number of antipsychotics and anxiolytics than those with bipolar II disorder (p < 0.001). Presence of depressive symptoms was associated with an increase in antidepressant use (p < 0.001). Bipolar disorder real-life management practice, irrespective of region, shows a delay in diagnosis and an overuse of antidepressants. Clinical decision-making appears to be based on a multidimensional approach related to current symptomatology and type of bipolar disorder. PMID:27181262

  15. Towards a conceptual model of motorcyclists' Risk Awareness: a comparative study of riding experience effect on hazard detection and situational criticality assessment.

    Science.gov (United States)

    Bellet, Thierry; Banet, Aurélie

    2012-11-01

    This research investigates risk awareness abilities among different populations of motorcyclists. Risk awareness is defined here as an extension of the Situational Awareness theory applied to critical driving situations. This study is more particularly focused on two main cognitive abilities supporting risk awareness: hazard detection, corresponding to riders' skill to perceive critical event occurring in the road environment and to identify it as a threat, and situational criticality assessment, corresponding to a subjective assessment of the accident risk. From this theoretical framework, the aim is to compare motorcyclists' performances in risk awareness according to their experience in motorcycling. Four populations of motorcyclists are investigated: Professional (Policemen), Experienced riders, Novices, and Beginners. Method implemented is based of a set of 25 video sequences of driving situations presenting a risk of collision. Participants' task was firstly to stop the video film if they detect a hazard. Then, at the end of each sequence, they have also to assess the criticality of the driving situation as a whole, with a Likert scale (from 0 to 100% of criticality). Results obtained show that cognitive abilities in both (i) hazard detection and (ii) situational criticality assessment depend of the riding experience, and are learnt from two different timing. On one side, Professional and Experienced riders obtained better results than Novices and Beginners for hazard perception (i.e. shortest reaction time). In terms of situational criticality assessment, Beginners underestimate the situational risk and seem overconfident in their abilities to manage the situational risk, against Novices, Professional and Experienced riders, who have better competences in criticality assessment. From these empirical results, a conceptual model of motorcyclists' Risk Awareness is proposed. Copyright © 2011 Elsevier Ltd. All rights reserved.

  16. Initial Development of a Model of Care and Support for Primary School Children in Changing Familial Situations: A Hong Kong Hybrid Case

    Science.gov (United States)

    Luk-Fong, Pattie Yuk Yee

    2008-01-01

    This paper proposes an initial model for the care and support of primary school children coping with family situations and family changes. The model is built on existing counselling literature, incorporating the perceptions of teachers, children and parents on their needs for support and a small empirical study by the author on teachers'…

  17. Experimental Section: On the magnetic field distribution generated by a dipolar current source situated in a realistically shaped compartment model of the head

    NARCIS (Netherlands)

    Meijs, J.W.H.; Bosch, F.G.C.; Peters, M.J.; Lopes da silva, F.H.

    1987-01-01

    The magnetic field distribution around the head is simulated using a realistically shaped compartment model of the head. The model is based on magnetic resonance images. The 3 compartments describe the brain, the skull and the scalp. The source is represented by a current dipole situated in the

  18. Soil Moisture Data Assimilation in the NASA Land Information System for Local Modeling Applications and Improved Situational Awareness

    Science.gov (United States)

    Case, Jonathan L.; Blakenship, Clay B.; Zavodsky, Bradley T.

    2014-01-01

    As part of the NASA Soil Moisture Active Passive (SMAP) Early Adopter (EA) program, the NASA Shortterm Prediction Research and Transition (SPoRT) Center has implemented a data assimilation (DA) routine into the NASA Land Information System (LIS) for soil moisture retrievals from the European Space Agency's Soil Moisture Ocean Salinity (SMOS) satellite. The SMAP EA program promotes application-driven research to provide a fundamental understanding of how SMAP data products will be used to improve decision-making at operational agencies. SPoRT has partnered with select NOAA/NWS Weather Forecast Offices (WFOs) that use output from a real-time regional configuration of LIS, without soil moisture DA, to initialize local numerical weather prediction (NWP) models and enhance situational awareness. Improvements to local NWP with the current LIS have been demonstrated; however, a better representation of the land surface through assimilation of SMOS (and eventually SMAP) retrievals is expected to lead to further model improvement, particularly during warm-season months. SPoRT will collaborate with select WFOs to assess the impact of soil moisture DA on operational forecast situations. Assimilation of the legacy SMOS instrument data provides an opportunity to develop expertise in preparation for using SMAP data products shortly after the scheduled launch on 5 November 2014. SMOS contains a passive L-band radiometer that is used to retrieve surface soil moisture at 35-km resolution with an accuracy of 0.04 cu cm cm (exp -3). SMAP will feature a comparable passive L-band instrument in conjunction with a 3-km resolution active radar component of slightly degraded accuracy. A combined radar-radiometer product will offer unprecedented global coverage of soil moisture at high spatial resolution (9 km) for hydrometeorological applications, balancing the resolution and accuracy of the active and passive instruments, respectively. The LIS software framework manages land surface model

  19. Situations of dwelling

    DEFF Research Database (Denmark)

    Welling, Helen; Duelund Mortensen, Peder; Wiell Nordberg, Lene

    2006-01-01

    values and needs in differnet situations, lifestyles and stages. The study is based on information from users in new housing schemes in and around Copenhagen - 'open building' dwellings that reveal a variety of approaches to these problems? The analysis of the dwellings show that the architecture...... of the 'open dwelling' is dependent on three basic conditions: the static condition, the suitable condition and the situational condition. Each condition has its own powerful way of articulation. Our aim is to translate the observations of the projects in concepts and models that are applicable in new projects....

  20. Situated Learning as a Model for the Design of an Interactive Multimedia Program on Medication Administration for Nurses.

    Science.gov (United States)

    Stillman, Gloria; Alison, Justine; Croker, Felicity; Tonkin, Carol

    1998-01-01

    This case study examines the use of a situated learning framework providing authentic contexts, authentic activities, access to expert performance, and opportunities for student reflection for the design of an interactive multimedia program on medication administration for nursing students. (PEN)

  1. Situated clinical cognition.

    Science.gov (United States)

    Timpka, T

    1995-10-01

    The features characterizing study of clinical cognition in situ are formulated as: Re-cognition of context, culture, history and affect. Socializing and phenomenalistic elements are again included in the research agenda. Interest for representations: an analysis level is reserved for the symbols, rules and images relevant to define in models of clinical cognition. De-emphasis on computer modeling: investigations focus on the 'functional systems' in which computers are involved. Rootedness in classical philosophical problems: issues concerning situated clinical cognition are connected to the width of available theoretical literature. Belief in interdisciplinary studies: productive interactions between the new and traditional disciplines is anticipated, implying that new shared methods have to be developed. When scientific perspectives are broadened, a new balance has to be found between the relevance of the subject of study and methodological rigor. The situated clinical cognition framework is to allow for moving between models, theories, and perspectives, as it does not presuppose a singular model of clinical thinking.

  2. Work Practice Simulation of Complex Human-Automation Systems in Safety Critical Situations: The Brahms Generalized berlingen Model

    Science.gov (United States)

    Clancey, William J.; Linde, Charlotte; Seah, Chin; Shafto, Michael

    2013-01-01

    anomalous condition, as occurred during the accident. Brahms-GUeM thus implicitly defines a class of scenarios, which include as an instance what occurred at Überlingen. Brahms-GUeM is a modeling framework enabling "what if" analysis of alternative work system configurations and thus facilitating design of alternative operations concepts. It enables subsequent adaption (reusing simulation components) for modeling and simulating NextGen scenarios. This project demonstrates that BRAHMS provides the capacity to model the complexity of air transportation systems, going beyond idealized and simple flights to include for example the interaction of pilots and ATCOs. The research shows clearly that verification and validation must include the entire work system, on the one hand to check that mechanisms exist to handle failures of communication and alerting subsystems and/or failures of people to notice, comprehend, or communicate problematic (unsafe) situations; but also to understand how people must use their own judgment in relating fallible systems like TCAS to other sources of information and thus to evaluate how the unreliability of automation affects system safety. The simulation shows in particular that distributed agents (people and automated systems) acting without knowledge of each others' actions can create a complex, dynamic system whose interactive behavior is unexpected and is changing too quickly to comprehend and control.

  3. AB036. Real-life experience of COPD patients on ease and accuracy of inhaler use: the REAL survey

    Science.gov (United States)

    Keininger, Dorothy L.; Price, David; Viswanad, Boomi; Gasser, Matthias; Walda, Susann

    2016-01-01

    Background Many patients with chronic obstructive pulmonary disease (COPD) achieve incomplete benefit from their treatment, due to reasons including inadequate device training or incorrect inhaler technique. Dosing frequency has also been shown to impact COPD treatment compliance with inhaler overuse and underuse being the most common form of noncompliance. Between 28–68% of patients do not use their inhalers correctly, and 39–67% of health care professionals (HCPs) do not effectively train patients to correctly use their inhalers. This makes patients prone to committing inhaler use errors and may negatively impact treatment compliance. We conducted a computer-assisted telephonic survey in patients with COPD to evaluate patient-reported insights on real life aspects of inhaler use, training and check for correct use by HCP, device attributes and patient-reported compliance of inhaler or medication use. Methods Patients from 9 countries, diagnosed with mild to very severe COPD and using maintenance inhaled treatment (via Breezhaler®, Ellipta®, Genuair®, Respimat®) were included in this survey. Patient-reported data on correct inhaler use (training and check), inhalation pattern, and device attributes (ease of use and confidence of inhaling full dose), compliance and potential underuse or overuse was collected. Chi-square test was performed for testing significance and z-test was used for comparisons of proportions (significance level: alphaEllipta® =191; Genuair® = 194; Respimat® =201) with mild to very severe COPD with a mean (±SD) age 56±9.8 years, completed the survey. Approximately, 30% of all patients reported not receiving any inhaler use training. Of the 70%, who received training on inhaler use, 83% felt that the demonstration of inhaler use was very helpful, followed by videos (58%), instructions for use (51%) and leaflets (34%), irrespective of the device used. About 29% of all patients reported never being checked for correct inhaler

  4. Management of COPD in the UK primary-care setting: an analysis of real-life prescribing patterns

    Directory of Open Access Journals (Sweden)

    Price D

    2014-08-01

    Full Text Available David Price,1 Daniel West,2 Guy Brusselle,3–5 Kevin Gruffydd-Jones,6 Rupert Jones,7 Marc Miravitlles,8 Andrea Rossi,9 Catherine Hutton,2 Valerie L Ashton,2 Rebecca Stewart,2 Katsiaryna Bichel2 1Centre of Academic Primary Care, University of Aberdeen, Aberdeen, UK; 2Research in Real-Life Ltd, Cambridge, UK; 3Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium; 4Department of Epidemiology, 5Department of Respiratory Medicine, Erasmus Medical Center, Rotterdam, the Netherlands; 6Box Surgery, Wiltshire, UK; 7Centre for Clinical Trials and Health Research – Translational and Stratified Medicine, Plymouth University Peninsula Schools of Medicine and Dentistry, Plymouth UK; 8Department of Pneumology, Hospital Universitari Vall d'Hebron, Ciber de Enfermedades Respiratorias (CIBERES, Barcelona, Spain; 9Pulmonary Unit, Cardiovascular and Thoracic Department, University and General Hospital, Verona, Italy Background: Despite the availability of national and international guidelines, evidence suggests that chronic obstructive pulmonary disease (COPD treatment is not always prescribed according to recommendations. This study evaluated the current management of patients with COPD using a large UK primary-care database. Methods: This analysis used electronic patient records and patient-completed questionnaires from the Optimum Patient Care Research Database. Data on current management were analyzed by the Global Initiative for Chronic Obstructive Lung Disease (GOLD group and presence or absence of a concomitant asthma diagnosis, in patients with a COPD diagnosis at ≥35 years of age and with spirometry results supportive of the COPD diagnosis. Results: A total of 24,957 patients were analyzed, of whom 13,557 (54.3% had moderate airflow limitation (GOLD Stage 2 COPD. The proportion of patients not receiving pharmacologic treatment for COPD was 17.0% in the total COPD population and 17.7% in the GOLD Stage 2 subset. Approximately

  5. The narghile (hookah, shisha, goza) epidemic and the need for clearing up confusion and solving problems related with model building of social situations.

    Science.gov (United States)

    Chaouachi, Kamal T

    2007-10-22

    Many biomedical studies of the past seven years have failed in giving a sound picture of what hookah (shisha, narghile, goza) smoke and smoking are. The reasons are many: from the widespread use of a confusing neologism ("waterpipe") instead of the few clear and natural words used for centuries by indigenous and non-indigenous people in their real life, to the use of artificial smoking (machines) instead of relying on quantitative and qualitative analysis of toxicants directly performed on real hookah smokers.

  6. Situational theory of leadership.

    Science.gov (United States)

    Waller, D J; Smith, S R; Warnock, J T

    1989-11-01

    The situational theory of leadership and the LEAD instruments for determining leadership style are explained, and the application of the situational leadership theory to the process of planning for and implementing organizational change is described. Early studies of leadership style identified two basic leadership styles: the task-oriented autocratic style and the relationship-oriented democratic style. Subsequent research found that most leaders exhibited one of four combinations of task and relationship behaviors. The situational leadership theory holds that the difference between the effectiveness and ineffectiveness of the four leadership styles is the appropriateness of the leader's behavior to the particular situation in which it is used. The task maturity of the individual or group being led must also be accounted for; follower readiness is defined in terms of the capacity to set high but attainable goals, willingness or ability to accept responsibility, and possession of the necessary education or experience for a specific task. A person's leadership style, range, and adaptability can be determined from the LEADSelf and LEADOther questionnaires. By applying the principles of the situational leadership theory and adapting their managerial styles to specific tasks and levels of follower maturity, the authors were successful in implementing 24-hour pharmacokinetic dosing services provided by staff pharmacists with little previous experience in clinical services. The situational leadership model enables a leader to identify a task, set goals, determine the task maturity of the individual or group, select an appropriate leadership style, and modify the style as change occurs. Pharmacy managers can use this model when implementing clinical pharmacy services.

  7. Modelling gait processes as a combination of sensory-motor and cognitive controls in an attempt to describe accidents on the level in occupational situations.

    Science.gov (United States)

    Sicre, Alexandrine; Leclercq, Sylvie; Gaudez, Clarisse; Gauthier, Gabriel M; Vercher, Jean-Louis; Bourdin, Christophe

    2008-01-01

    In occupational situations, accidents referred to as accidents on the level (AoLs) occur most of the time when locomotion control fails. This control is determined by the interactions between the operator and the environment, the task and the used tools. Hence, AoLs prevention requires developing ways to optimise these interactions. More fundamentally, AoLs prevention requires understanding locomotion control in situations where this control is at sake, that is in situations involving one or more AoLs factors. The purpose of this article is to propose a comprehensive model for the control of locomotion in occupational environments. This model featuring the operator, the task and the working space should be an appropriate tool to understand AoLs in the scope of their prevention. Firstly, we describe what occupational AoLs are. In a second part, we present a review of the theoretical and experimental knowledge related to the locomotion system through the various means developed by the Central Nervous System to cope with perturbations of the environment and/or particular constraints from the task. Finally, we propose a simplified systemic model presenting the various levels of control (sensory-motor to cognitive levels) describing locomotion in occupational situations, and we suggest experiments likely to produce the appropriate data to construct the final comprehensive model.

  8. On-treatment and off-treatment efficacy of entecavir in a real-life cohort of chronic hepatitis B patients.

    Science.gov (United States)

    Park, Chung-Hwa; Kim, Hee Yeon; Lee, Sung Won; Song, Do Seon; Song, Myeong Jun; Kwon, Jung Hyun; You, Chan Ran; Jang, Jeong Won; Kim, Chang Wook; Choi, Sang Wook; Bae, Si Hyun; Choi, Jong Young; Yoon, Seung Kew

    2016-10-01

    Entecavir (ETV) is a potent nucleoside analogue with high genetic barrier to resistance. In this study, real-life clinical experiences in the long-term use of ETV and the durability of its off-treatment effectiveness were analyzed. This study was based on a large real-life cohort of 2240 chronic hepatitis B patients treated with ETV between January 2006 and December 2012 using a centralized electronic data repository. Among 2240 patients, 804 patients were treatment naive and underwent ETV monotherapy. Their mean treatment duration was 712±493 days, with a cumulative proportion of patients achieving HBV DNA less than 300 copies/ml in 85.8, 95.7, and 97.6% at years 1, 2, and 3, respectively. Predictors for earlier virologic response were female sex, lower HBV DNA, higher alanine transaminase, lower platelet count, and HBeAg negativity at baseline. In patients who achieved virologic response and HBeAg loss, the cumulative relapse rate was 91.3% in 2 years after the cessation of treatment. During the treatment, 34 patients developed hepatocellular carcinoma, among whom 30 patients had cirrhosis before treatment initiation. ETV treatment showed efficient virologic response as the treatment duration was extended, but off-treatment efficacy was not durable, and the antiviral treatment showed some limitation in preventing hepatocellular carcinoma among liver cirrhosis patients, implying that treatment cessation should be taken into consideration more carefully. This study from a real-life cohort may provide data on treating chronic hepatitis B patients more close to everyday clinical practice.

  9. Thoracic Injury Risk as a Function of Crash Severity - Car-to-car Side Impact Tests with WorldSID Compared to Real-life Crashes.

    Science.gov (United States)

    Sunnevång, Cecilia; Rosén, Erik; Boström, Ola; Lechelt, Ulf

    2010-01-01

    Side airbags reduce the risk of fatal injury by approximately 30%. Due to limited real-life data the risk reducing effect for serious injury has not yet been established. Since side airbags are mainly designed and validated for crash severities used in available test procedures little is known regarding the protective effect when severity increases.The objective of this study was to understand for which crash severities AIS3+ thorax occupant protection in car-to-car nearside collisions need to and can be improved. The aim was fulfilled by means of real life data, for older cars without side airbag, and a series of car-to-car tests performed with the WorldSID 50%-ile in modern and older cars at different impact speeds.The real life data showed that the risk of AIS3+ injury was highest for the thorax followed by the pelvis and head. For both non-senior and senior occupants, most thorax injuries were sustained at lateral delta-v from 20 km/h to 40 km/h. In this severity range, senior occupants were found to have approximately four times higher risk of thoracic injury than non-senior occupants. The crash tests at lateral impact speed 55 km/h (delta-v 32 km/h) confirmed the improved performance at severities represented in current legal and rating tests. The structural integrity of the modern car impacted at 70 km/h showed a potential for improved side impact protection by interior countermeasures.

  10. The real-life number of neonatal doses of Bacille Calmette-Guérin vaccine in a 20-dose vial

    Science.gov (United States)

    Schaltz-Buchholzer, Frederik; Frankel, Hannah Nørtoft; Benn, Christine Stabell

    2017-01-01

    ABSTRACT Background: Reducing vaccine wastage is important. Bacille Calmette-Guérin (BCG) vaccine is produced in vials of 20 infant doses. The reconstituted vaccine is discarded after 4–6 hours. Therefore, to reduce vaccine wastage, a 20-dose vial of BCG is often only opened if at least 10–12 infants are present, jeopardising BCG vaccination coverage and timely vaccination. We observed that nurses were not able to withdraw 20 doses from the vials and aimed to quantify how many doses could be obtained from these vials by experienced nurses under real-life circumstances. Methods: At the maternity ward of the national hospital in Guinea-Bissau, since 2002 the same two nurses have been vaccinating all eligible children with BCG before discharge. During a month in 2015, within a randomised trial comparing BCG-Denmark and BCG-Russia, we registered how many doses the nurses were able to withdraw from the two types of vaccine vials. Results: The median number of doses which it was possible to withdraw from the vials was 13 (range 11–17): 13 (11–16) for BCG-Denmark (based on 39 vials) and 15 (12–17) for BCG-Russia (based on 29 vials). Conclusions: In real life, experienced nurses could only obtain 13–15 doses from the 20-dose vials. Thus, vaccine wastage is much lower than assumed. Adjusting practice to the real-life number of doses would immediately suggest vials should be opened if 7 rather than 10 infants are present. As other studies have indicated that BCG may have beneficial non-specific effects on overall mortality, the potential gain by opening a 20-dose vial even for one child may be considerable. PMID:28169606

  11. Efficacy and safety of telaprevir (TVR) triple therapy in a 'real-life' cohort of 102 patients with HCV genotype 1: interim analysis after 24 weeks of treatment.

    Science.gov (United States)

    Werner, C R; Franz, C; Egetemeyr, D P; Janke-Maier, P; Malek, N P; Lauer, U M; Berg, C P

    2014-05-01

    Since 2011, telaprevir (TVR)-based triple therapy is the new treatment standard for hepatitis C genotype 1 virus infection. The aim of our retrospective interim analysis encompassing the first 24 weeks on TVR-based triple therapy was to assess 'real-life' antiviral efficacy and side effects in a large single-centre cohort, both in comparison with the data obtained in large prospective clinical trials. In total, we treated 102 patients: 24 treatment-naïve patients, 58 patients pretreated with PEG-IFN/RBV (thereof: 28 with nonresponse, 25 with relapse, five unknown) and 20 patients who previously had received nonpegylated interferon. 74 of 102 patients were assigned with HCV genotype 1b; 34 of 102 patients were treated in the context of liver cirrhosis. 72 of 102 patients have reached treatment week 24 (mean treatment duration 31 weeks). In the ITT analysis, overall response rates were at: week 4: 66%; week 12: 85%; and week 24: 78%. So far, 24 patients discontinued treatment prematurely, of those, 10 patients were due to virological failure. Haematological side effects were frequent (40% anaemia), as were 'flu-like' symptoms (94%), rash (65%) and pruritus (79%). According to our interim ITT analysis encompassing up to 24 weeks of TVR-based triple therapy, our 'real-life' antiviral effects are comparable to the results of large multicentric clinical trials. However, TVR-based triple therapy exhibited a high frequency of side effects requiring multiple therapeutic interventions. Notably, in our 'real-life' cohort, no lethal case was observed so far.

  12. The use of incretins and fractures - a meta-analysis on population-based real life data

    DEFF Research Database (Denmark)

    Driessen, J H M; de Vries, F; van Onzenoort, H;

    2016-01-01

    The aim of the present study was to estimate the effect of incretins on fracture risk in the real world situation by meta-analysis of the available population-based cohort data. Pubmed and Embase were searched for original articles investigating use of incretin agents, and fracture risk up...... of fracture: pooled relative risk [pooled RR (95% CI): 1.02 (0.91 to 1.13) and 1.03 (0.87 to 1.22)], respectively. This meta-analysis demonstrated that current use of incretin agents, was not associated with decreased fracture risk. Our findings show the value of representative real-world populations...

  13. A new model of information behaviour based on the Search Situation Transition schema Information searching, Information behaviour, Behavior, Information retrieval, Information seeking

    Directory of Open Access Journals (Sweden)

    Nils Pharo

    2004-01-01

    Full Text Available This paper presents a conceptual model of information behaviour. The model is part of the Search Situation Transition method schema. The method schema is developed to discover and analyse interplay between phenomena traditionally analysed as factors influencing either information retrieval or information seeking. In this paper the focus is on the model's five main categories: the work task, the searcher, the social/organisational environment, the search task, and the search process. In particular, the search process and its sub-categories search situation and transition and the relationship between these are discussed. To justify the method schema an empirical study was designed according to the schema's specifications. In the paper a subset of the study is presented analysing the effects of work tasks on Web information searching. Findings from this small-scale study indicate a strong relationship between the work task goal and the level of relevance used for judging resources during search processes.

  14. 教育回归生活世界研究述评%A Summary and Analysis of the Education Return to the Real-life World

    Institute of Scientific and Technical Information of China (English)

    刘娜娜

    2012-01-01

    The two world wars and the Great Depression shaked the people's belief that scientiiic expertise alone could create a prosperous and orderly world. After World War II, the academic world turned with new enthusiasm to the research of the return to the real-life world. Meanwhile, the education's return to the real-life world became the central research subject in the educational field. On the basis of the existing literature, the author makes a comprehensive summary, analysis and reflection on this topic.%两次世界大战和经济大萧条动摇了人们对单靠科学知识就能创造出繁荣有序的世界这一信心。二战后,学界把研究重心转入回归生活世界的研究。教育回归生活世界也成为教育领域密切关注的研究课题,在梳理现有文献的基础上,对国内外“教育回归生活世界”的研究进行了深入的探源、分析与反思。

  15. A sensitive, selective and rapid determination of lead(II) ions in real-life samples using an electrochemically reduced graphene oxide-graphite reinforced carbon electrode.

    Science.gov (United States)

    Hamsawahini, Kunashegaran; Sathishkumar, Palanivel; Ahamad, Rahmalan; Yusoff, Abdull Rahim Mohd

    2015-11-01

    In this study, a sensitive and cost-effective electrochemically reduced graphene oxide (ErGO) on graphite reinforced carbon (GRC) was developed for the detection of lead (Pb(II)) ions present in the real-life samples. A film of graphene oxide (GO) was drop-casted on GRC and their electrochemical properties were investigated using cyclic voltammetry (CV), amperometry and square wave voltammetry (SWV). Factors influencing the detection of Pb(II) ions, such as grades of GRC, constant applied cathodic potential (CACP), concentration of hydrochloric acid and drop-casting drying time were optimised. GO is irreversibly reduced in the range of -0.7 V to -1.6 V vs Ag/AgCl (3 M) in acidic condition. The results showed that the reduction behaviour of GO contributed to the high sensitivity of Pb(II) ions detection even at nanomolar level. The ErGO-GRC showed the detection limit of 0.5 nM and linear range of 3-15 nM in HCl (1 M). The developed electrode has potential to be a good candidate for the determination of Pb(II) ions in different aqueous system. The proposed method gives a good recovery rate of Pb(II) ions in real-life water samples such as tap water and river water.

  16. Real-life Data on Patient Characteristics, Cost and Effectiveness of Field-directed Treatment for Actinic Keratoses: An Observational Study.

    Science.gov (United States)

    van Rijsingen, Margit C J; Seubring, Inge; Grutters, Janneke P C; Maessen-Visch, M Birgitte; Alkemade, Hans A C; van Doorn, Remco; Groenewoud, Hans; van de Kerkhof, Peter C M; van der Wilt, Gert Jan; Gerritsen, Marie-Jeanne P

    2016-03-01

    Actinic keratoses (AK) occur frequently; however, real-life clinical data on personalized treatment choice and costs are scarce. This multicentre one-year observational study investigated patient-characteristics, cost and effectiveness of methylaminolaevulinate photodynamic therapy (MAL-PDT), imiquimod (IMI) and 5-fluorour-acil (5-FU) in patients with AKs on the face/scalp. A total of 104 patients preferred MAL-PDT, 106 preferred IMI and 110 preferred 5-FU. At baseline, significant differences between treatment groups were found; most patients were severely affected (mean 32.5 AK in PDT-group, 20.2 in IMI-group, 22.8 in 5-FU-group). A mean reduction in lesions of 81% after MAL-PDT, 82% after IMI and 88% after 5-FU was found after one year. Annual costs were €1,950 for MAL-PDT, €877 for IMI and €738 for 5-FU. These results show that, compared with clinical trials, in the real-life clinical setting AK patients are usually more severely affected and treatment costs are much higher. Furthermore, patient characteristics are important factors in treatment choice.

  17. Patient education improves adherence to peg-interferon and ribavirin in chronic genotype 2 or 3 hepatitis C virus infection: A prospective, real-life, observational study

    Institute of Scientific and Technical Information of China (English)

    Patrice Cacoub; Denis Ouzan; Pascal Melin; Jean-Philippe Lang; Michel Rotily; Thierry Fontanges; Marina Varastet; Michel Chousterman; Patrick Marcellin

    2008-01-01

    AIM: To evaluate the impact of therapeutic education on adherence to antiviral treatment and sustained virological response (SVR) in a real-life setting in genotype 2/3 hepatitis C, as there are few adherence data in genotype 2/3 infection, even from randomized trials. METHODS: This prospective survey included genotype 2/3 patients who received peg-interferon alfa-2b and ribavirin. There was no intervention. Adherence was self-reported over the past 4 wk (peg-interferon) or 7 d (ribavirin). Adherence to bitherapy was defined as adherence to the two drugs for≥20 wk. SVR was defined as undetectable RNA≥12 wk after the end of treatment. RESULTS: 370/674 patients received education during the first 3 mo of treatment. After 6 mo, adherence to bitherapy was higher in educated patients (61% vs 47%, P=0.01). Adherence to peg-interferon was 78% vs 69% (P=0.06). Adherence to ribavirin was 70% vs 56% (P=0.006). The SVR (77% vs 70%, P = 0.05) and relapse (10% w 16%, P = 0.09) rates tended to be improved. After adjustment for baseline differences, education improved adherence [Odds ratio (OR) 1.58, P=0.04] but not the SVR (OR 1.54, P=0.06). CONCLUSION: In genotype 2/3 patients, therapeutic education helped maintain real-life adherence to bitherapy.

  18. Stereotactic radiotherapy in neovascular age-related macular degeneration: Real-life efficacy and morphological evaluation of the outer retina-choroid complex.

    Science.gov (United States)

    Ranjbar, Mahdy; Kurz, Maximilian; Holzhey, Annekatrin; Melchert, Corinna; Rades, Dirk; Grisanti, Salvatore

    2016-12-01

    Stereotactic radiotherapy (SRT) is a new approach to treat neovascular age-related macular degeneration (nAMD). The INTREPID trial suggested that SRT could reduce the frequency of regular intravitreal injections (IVIs) with antivascular endothelial growth factor drugs, which are necessary to control disease activity. However, the efficacy of SRT in nAMD and resulting morphological changes have not been validated under real-life circumstances, an issue, which we would like to address in this retrospective analysis.Patients who met the INTREPID criteria for best responders were eligible for SRT. A total of 32 eyes of 32 patients were treated. Thereafter, patients were examined monthly for 12 months and received pro re nata IVI of aflibercept or ranibizumab. Outcome measures were: mean number of injections, best-corrected visual acuity, and morphological changes of the outer retina-choroid complex as well as patient safety.Mean number of IVI decreased by almost 50% during the 12 months after SRT compared to the year before, whereas visual acuity increased by one line (logMAR). Morphological evaluation showed that most changes affect outer retinal layers.Stereotactic radiotherapy significantly reduced IVI retreatment in nAMD patients under real-life circumstances. Therefore, SRT might be the first step to stop visual loss as a result of IVI undertreatment, which is a major risk.

  19. Sofosbuvir plus simeprevir for the treatment of HCV genotype 4 patients with advanced fibrosis or compensated cirrhosis is highly efficacious in real life.

    Science.gov (United States)

    Willemse, S B; Baak, L C; Kuiken, S D; van der Sluys Veer, A; Lettinga, K D; van der Meer, J T M; Depla, A C T M; Tuynman, H; van Nieuwkerk, C M J; Schinkel, C J; Kwa, D; Reesink, H W; van der Valk, M

    2016-12-01

    Chronic hepatitis C virus (HCV) infection is a major cause of chronic liver disease and liver-related death. Recently, multiple regimens of different direct-acting antiviral agents (DAAs) have been registered. Although treatment with sofosbuvir (SOF) and simeprevir (SMV) is registered for the treatment of genotype 4 patients in some countries, data on efficacy of this combination are lacking. We aimed to assess the efficacy of SOF and SMV with or without RBV during 12 weeks in a real-life cohort of genotype 4 HCV patients. A retrospective multicentre observational study was conducted in 4 hospitals in Amsterdam, the Netherlands, including patients with advanced liver fibrosis or liver cirrhosis treated with SOF plus SMV with or without RBV during 12 weeks for a genotype 4 chronic HCV infection from 1 January 2015 to 1 August 2015. Sustained viral response (SVR) was established at week 12 after end of treatment. A total of 53 patients with genotype 4 HCV infection, treatment naïve and experienced, were included. SVR was achieved in 49 of 53 patients (92%). The four failures all had a virological relapse and did not receive ribavirin. Three were nonresponder to earlier interferon-based treatment, and one was treatment naive. In this real-life cohort of patients with HCV genotype 4 infection and advanced liver fibrosis/cirrhosis, we show that treatment with SOF and SMV is effective. The addition of RBV could be considered in treatment-experienced patients as recommended in guidelines.

  20. Factors influencing the choice of first- and second-line biologic therapy for the treatment of rheumatoid arthritis: real-life data from the Italian LORHEN Registry.

    Science.gov (United States)

    Monti, Sara; Klersy, Catherine; Gorla, Roberto; Sarzi-Puttini, Piercarlo; Atzeni, Fabiola; Pellerito, Raffaele; Fusaro, Enrico; Paolazzi, Giuseppe; Rocchetta, Pier Andrea; Favalli, Ennio Giulio; Marchesoni, Antonio; Caporali, Roberto

    2017-04-01

    According to international recommendations, the selection of the biologic disease modifying anti-rheumatic drug (bDMARD) for rheumatoid arthritis (RA) is mainly left to the clinician's preference. We analyzed the real-life factors influencing the first-line choice or the switching strategy, focusing on the prescription of abatacept (ABA) or tocilizumab (TCZ) compared to TNFα inhibitors (TNFi). Patients enrolled in the Lombardy Rheumatology Network (LORHEN) Registry after January 1, 2010, when all considered bDMARD agents were available, were included. The population was divided into "first-" and "second-line" bDMARD. We included 1910 patients (first line n = 1264, second line n = 646). Age was higher in ABA or TCZ vs TNFi treated patients (p second-line treatment, higher age, dyslipidemia, pulmonary disease, other comorbidities, and extra-articular RA manifestations were associated with ABA compared to TNFi. TCZ was associated with a second-line treatment, higher age, and more severe disease activity. Stopping the first bDMARD due to adverse events (AE) influenced the choice towards ABA. In real life, higher age and comorbidities influence the choice towards ABA and TCZ compared to TNFi. ABA was preferred in case of suspension of previous treatments due to AE. After failing a first-line TNFi, swapping to a different mechanism of action is more common.

  1. Cruel intentions on television and in real life: can viewing indirect aggression increase viewers' subsequent indirect aggression?

    Science.gov (United States)

    Coyne, Sarah M; Archer, John; Eslea, Mike

    2004-07-01

    Numerous studies have shown that viewing violence in the media can influence an individual's subsequent aggression, but none have examined the effect of viewing indirect aggression. This study examines the immediate effect of viewing indirect and direct aggression on subsequent indirect aggression among 199 children ages 11 to 14 years. They were shown an indirect, direct, or no-aggression video and their subsequent indirect aggression was measured by negative evaluation of a confederate and responses to a vignette. Participants viewing indirect or direct aggression gave a more negative evaluation of and less money to a confederate than participants viewing no-aggression. Participants viewing indirect aggression gave less money to the confederate than those viewing direct aggression. Participants viewing indirect aggression gave more indirectly aggressive responses to an ambiguous situation and participants viewing direct aggression gave more directly aggressive responses. This study provides the first evidence that viewing indirect aggression in the media can have an immediate impact on subsequent aggression.

  2. Long term continuous positive airway pressure (CPAP) and noninvasive ventilation (NIV) in children: Initiation criteria in real life.

    Science.gov (United States)

    Amaddeo, A; Moreau, J; Frapin, A; Khirani, S; Felix, O; Fernandez-Bolanos, M; Ramirez, A; Fauroux, B

    2016-09-01

    Long term noninvasive continuous positive airway pressure (CPAP) and noninvasive ventilation (NIV) are increasingly used in children but limited information is available on the criteria and conditions leading to the initiation of these treatments. The aim of the study is to describe the objective overnight respiratory parameters and clinical situations that led to the initiation of CPAP/NIV in a pediatric NIV unit. Retrospective analysis of the data of all the children discharged on home CPAP/NIV over a 1 year period. Seventy-six patients were started on CPAP (n = 64) or NIV (n = 12). CPAP/NIV was initiated because of CPAP/NIV weaning failure (Acute group) in 15 patients. None of these patients had an overnight gas exchange or sleep study before CPAP/NIV initiation. In 18 patients, CPAP/NIV was initiated on abnormal nocturnal gas exchange alone (Subacute group). These patients had a median of three of the following five overnight gas exchange abnormalities: minimal pulse oximetry (SpO2 ) transcutaneous carbon dioxide (PtcCO2 ) >50 mmHg, time spent with SpO2 50 mmHg ≥2% of recording time, oxygen desaturation index >1.4/hr. In the last 43 patients, CPAP/NIV was initiated after an abnormal sleep study (Chronic group) on a mean of four of the aforementioned criteria and an apnea-hypopnea index >10/hr. In clinical practice, CPAP/NIV was initiated in an acute, subacute and chronic setting with most patients having an association of several abnormal gas exchange or sleep study parameters. Future studies should evaluate the effectiveness and benefits of CPAP/NIV according to the clinical situation and initiation criteria. Pediatr Pulmonol. 2016; 51:968-974. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  3. Management models for the future

    DEFF Research Database (Denmark)

    Eskildsen, Jacob Kjær; van Pijkeren, Michel

    2009-01-01

    outline will be provided of each of the twelve business contributions in this volume. The experiences recorded in the following chapters are wide-ranging. They cover know-how with national quality award models; management models for fair trade, corporate social responsibility, organisational excellence......" theoretical framework that can be used to observe, create and assess a real life organizational 'situation' in order to make desired (future) improvements. We also argue that five common requirements can be used to appraise the applicability of a framework claiming to be a management model. Thereafter a brief...... and various aspects of an organisations' value chain. The volume makes available an intriguing journey into the application of management models in different organizational and environmental contexts - a great learning experience for anyone who undertakes it....

  4. Theoretical Models of Generalized Quasispecies.

    Science.gov (United States)

    Wagner, Nathaniel; Atsmon-Raz, Yoav; Ashkenasy, Gonen

    2016-01-01

    Theoretical modeling of quasispecies has progressed in several directions. In this chapter, we review the works of Emmanuel Tannenbaum, who, together with Eugene Shakhnovich at Harvard University and later with colleagues and students at Ben-Gurion University in Beersheva, implemented one of the more useful approaches, by progressively setting up various formulations for the quasispecies model and solving them analytically. Our review will focus on these papers that have explored new models, assumed the relevant mathematical approximations, and proceeded to analytically solve for the steady-state solutions and run stochastic simulations . When applicable, these models were related to real-life problems and situations, including changing environments, presence of chemical mutagens, evolution of cancer and tumor cells , mutations in Escherichia coli, stem cells , chromosomal instability (CIN), propagation of antibiotic drug resistance , dynamics of bacteria with plasmids , DNA proofreading mechanisms, and more.

  5. 基于ARIMA模型的网络安全威胁态势预测方法%Forecasting network security threat situation based on ARIMA model

    Institute of Scientific and Technical Information of China (English)

    李凯; 曹阳

    2012-01-01

    In order to solving the difficulty of forecasting the variation trend of the network security threat situation. The paper proposed a forecasting method based on the ARJMA model, which made use of the data of network security threat situation having the feature of time series. Firstly, this method analysed the information of services, leaks, and vulnerabilities and so on which were related to the network security. After this, the paper computed the network security threat situation reasonably. Based on that, forecasting the variation trend of the network security threat situation used a ARIMA model. The experiment results show that this method not only can reflect the true variation trend of network security threat situation,but also its prediction accuracy is higher.%针对网络安全威胁态势变化趋势预测的困难性,利用网络安全威胁态势值具有时间序列的特点,提出了一种基于ARIMA的模型的网络安全威胁态势预测方法.该方法首先分析服务、漏洞、弱点等与网络安全相关的信息,合理地计算出网络安全威胁态势值,进而使用ARIMA模型的预测方法对所得序列的变化趋势进行预测.实验结果表明,该方法不仅能够反映真实的网络安全威胁态势的变化趋势,而且其预测的精度也较高.

  6. The Narghile (Hookah, Shisha, Goza Epidemic and the Need for Clearing up Confusion and Solving Problems Related with Model Building of Social Situations

    Directory of Open Access Journals (Sweden)

    Kamal T. Chaouachi

    2007-01-01

    Full Text Available Many biomedical studies of the past seven years have failed in giving a sound picture of what hookah (shisha, narghile, goza smoke and smoking are. The reasons are many: from the widespread use of a confusing neologism (“waterpipe” instead of the few clear and natural words used for centuries by indigenous and non-indigenous people in their real life, to the use of artificial smoking (machines instead of relying on quantitative and qualitative analysis of toxicants directly performed on real hookah smokers.

  7. The Situation Model and Problem Model in Arithmetic Problem Solving%论数学问题解决中情境模型与问题模型的关系

    Institute of Scientific and Technical Information of China (English)

    和美君; 刘儒德

    2012-01-01

    情境模型与问题模型是数学问题解决研究中的两个重要概念,前者是对问题所述情境的日常化的定性表征,后者是基于图式知识对问题关键变量的数量关系表征。本文介绍了两种模型的发展历史以及目前存在的争议,并提出未来研究需要解决的问题。%Situation model and problem model are two important concepts in arithmetic problem solving and representation. However, researchers have different opinions about their definitions, roles and relationships in the process of problem solving. Therefore, our aim is to talk about their development history, discriminate the concepts, and reveal the controversies and future study direction. On the basis of general text comprehension theory (Van Dijk & Kintsch, 1983), Kintsch and Greeno (1985)first proposed the construction of problem models in arithmetic problem solving research field. They argued that problem solvers would construct textbase and problem model, and the latter one was the only high-level representation problem solvers constructed. This left other researchers unsatisfied, and many began to express their own opinions and propose the concept of the situation model. Nathan, Kintsch, and Young (1992) argued that while Kintsch and Greeno(1985) placed too much emphasis on schemata and problem models, the situation model was very important for it could make explicit the implicit conditions in the problem, and could also monitor and even correct possible mistakes in problem models. Then, Moreau and Coquin-Viennot(2003)studied the nature of representation problem solvers constructed through the information types they chose when doing different tasks, and proved that when solving problems, students would construct different representations according to different task requirements, and meanwhile, the mathematical ability of students had a great impact on the their capability of choosing relevant information to construct

  8. 栅格化网络态势感知能力评估模型%Evaluation Model of Situational Awareness Ability for Grid Network

    Institute of Scientific and Technical Information of China (English)

    张慧文; 鲍广宇; 张义

    2013-01-01

    针对栅格化信息基础网络态势感知问题,构建了态势感知能力评估模型.首先结合信息化战争的特点,分析了栅格化信息基础网络的态势感知能力构成.然后分别从信息域和认知域建立了态势感知能力评估模型.在信息域,将信息质量的完备性、准确性和时效性三个方面作为信息能力的度量指标;在认知域,结合信息域量化模型,建立Logistic态势感知方程,描述态势感知质量随时间的变化情况.仿真结果能够体现完备性、准确性和时效性对提高态势感知质量的促进作用,验证了模型的合理性.%The components of situational awareness ability for the grid information network are analyzed, and models for e-valuating the ability of situational awareness are established both in the information domain and the cognitive domain. In the information domain, three aspects of information quantity including completeness, accuracy and timeliness are proposed to e-valuate the situational awareness ability. In the cognitive domain, the Logistic equation is established in combination with the quantitative analyses of the information domain in order to describe the change of the situational awareness quality from time to time. The simulation results show the promotion of completeness, accuracy and timeliness for the situational awareness quality, which verify its rationality.

  9. Modeling of the thermal transfer inside a porous environment: application to nuclear reactors in accident situation; Modelisation du transfert thermique dans un milieu poreux: application aux reacteurs nucleaires en situation accidentelle

    Energy Technology Data Exchange (ETDEWEB)

    Rubiolo, P.R

    2000-03-01

    The purpose of this report is to simulate heat exchanges occurring by conduction, by convection and by radiating in a porous medium made up of opaque particles in a semi-transparent fluid. Usually the determination of the macroscopic equations is based on homogenization techniques, but in the case of a major accident, the complexity of the problem is so overwhelming that semi-empirical methods are used to determine macroscopic coefficients. The author develops a new method to determine these coefficients, this method is based on the calculation of different tensors: the equivalent conductivity tensor, the radiative conductivity tensor, the thermal conductivity tensor and the heat exchange coefficient (h{sub sf}) between the solid phase and the fluid one. The first chapter briefly describes energy, impulse and mass balances. In the case of the energy balance the solid phase is not supposed to be in thermal equilibrium with the liquid phase. The second chapter presents an application of the porous media method to a one-dimensional and stationary problem, this application to a simple problem gives an idea of the performance of the method. The model allowing the calculation of h{sub sf} is developed, it is a wide range model. The second chapter ends with the presentation of the model allowing the computing of the effective conductivity of fuel rods. A comparison between results given by this new method and other numeric calculations or experimental data coming from benchmarks is presented in the third chapter. This chapter ends with the simulation of a reactor core in accidental situation, 2 cases are presented: with and without the presence of water steam. (A.C.)

  10. Long-acting muscarinic antagonist use in adults with asthma: real-life prescribing and outcomes of add-on therapy with tiotropium bromide

    Directory of Open Access Journals (Sweden)

    Price D

    2015-01-01

    Full Text Available David Price,1,2 Alan Kaplan,3 Rupert Jones,4 Daryl Freeman,5 Anne Burden,2 Shuna Gould,2 Julie von Ziegenweidt,2 Muzammil Ali,2 Christine King,2 Mike Thomas6 1Academic Centre of Primary Care, University of Aberdeen, Aberdeen, 2Research in Real-Life, Cambridge, UK; 3Family Physician Airways Group of Canada, Richmond Hill, ON, Canada; 4Centre for Clinical Trials and Health Research, Plymouth University, Plymouth, 5Norfolk Community Health and Care NHS Trust, Norwich, 6Primary Care Research, University of Southhampton, Southhampton, UK Background: Randomized controlled trials indicate that addition of a long-acting muscarinic antagonist (LAMA such as tiotropium may improve asthma control and reduce exacerbation risk in patients with poorly controlled asthma, but broader clinical studies are needed to investigate the effectiveness of LAMA in real-life asthma care. Methods: Medical records of adults with asthma (aged ≥18 years prescribed tiotropium were obtained from the UK Optimum Patient Care Research Database for the period 2001–2013. Patients diagnosed with chronic obstructive pulmonary disease were excluded, but no other clinical exclusions were applied. Two primary outcomes were compared in the year before (baseline and the year after (outcome addition of tiotropium: exacerbations (asthma-related hospital emergency department attendance or inpatient admission, or acute oral corticosteroid course and acute respiratory events (exacerbation or antibiotic prescription with lower respiratory consultation. Secondary outcomes included lung function test results and short-acting β2 agonist usage. The Wilcoxon signed-rank test was used for variables measured on the interval scale, the marginal homogeneity test for categorized variables, and the paired t-test for lung function indices. Results: Of the 2,042 study patients, 83% were prescribed an inhaled corticosteroid and 68% a long-acting ß2 agonist during the baseline year; 67% were prescribed

  11. Translation of a tailored nutrition and resistance exercise intervention for elderly people to a real-life setting: adaptation process and pilot study.

    Science.gov (United States)

    van Dongen, Ellen Ji; Leerlooijer, Joanne N; Steijns, Jan M; Tieland, Michael; de Groot, Lisette Cpgm; Haveman-Nies, Annemien

    2017-01-18

    Combining increased dietary protein intake and resistance exercise training for elderly people is a promising strategy to prevent or counteract the loss of muscle mass and decrease the risk of disabilities. Using findings from controlled interventions in a real-life setting requires adaptations to the intervention and working procedures of healthcare professionals (HCPs). The aim of this study is to adapt an efficacious intervention for elderly people to a real-life setting (phase one) and test the feasibility and potential impact of this prototype intervention in practice in a pilot study (phase two). The Intervention Mapping approach was used to guide the adaptation in phase one. Qualitative data were collected from the original researchers, target group, and HCPs, and information was used to decide whether and how specified intervention elements needed to be adapted. In phase two, a one-group pre-test post-test pilot study was conducted (n = 25 community-dwelling elderly), to elicit further improvements to the prototype intervention. The evaluation included participant questionnaires and measurements at baseline (T0) and follow-up (T1), registration forms, interviews, and focus group discussions (T1). Qualitative data for both phases were analysed using an inductive approach. Outcome measures included physical functioning, strength, body composition, and dietary intake. Change in outcomes was assessed using Wilcoxon signed-rank tests. The most important adaptations to the original intervention were the design of HCP training and extending the original protein supplementation with a broader nutrition programme aimed at increasing protein intake, facilitated by a dietician. Although the prototype intervention was appreciated by participants and professionals, and perceived applicable for implementation, the pilot study process evaluation resulted in further adaptations, mostly concerning recruitment, training session guidance, and the nutrition programme

  12. Inverted U-Shaped Dose-Response Curve of the Anxiolytic Effect of Cannabidiol during Public Speaking in Real Life

    Directory of Open Access Journals (Sweden)

    Antonio W. Zuardi

    2017-05-01

    Full Text Available The purpose of this study was to investigate whether the anxiolytic effect of cannabidiol (CBD in humans follows the same pattern of an inverted U-shaped dose-effect curve observed in many animal studies. Sixty healthy subjects of both sexes aged between 18 and 35 years were randomly assigned to five groups that received placebo, clonazepam (1 mg, and CBD (100, 300, and 900 mg. The subjects were underwent a test of public speaking in a real situation (TPSRS where each subject had to speak in front of a group formed by the remaining participants. Each subject completed the anxiety and sedation factors of the Visual Analog Mood Scale and had their blood pressure and heart rate recorded. These measures were obtained in five experimental sessions with 12 volunteers each. Each session had four steps at the following times (minutes after administration of the drug/placebo, as time 0: -5 (baseline, 80 (pre-test, 153 (speech, and 216 (post-speech. Repeated-measures analyses of variance showed that the TPSRS increased the subjective measures of anxiety, heart rate, and blood pressure. Student-Newman-Keuls test comparisons among the groups in each phase showed significant attenuation in anxiety scores relative to the placebo group in the group treated with clonazepam during the speech phase, and in the clonazepam and CBD 300 mg groups in the post-speech phase. Clonazepam was more sedative than CBD 300 and 900 mg and induced a smaller increase in systolic and diastolic blood pressure than CBD 300 mg. The results confirmed that the acute administration of CBD induced anxiolytic effects with a dose-dependent inverted U-shaped curve in healthy subjects, since the subjective anxiety measures were reduced with CBD 300 mg, but not with CBD 100 and 900 mg, in the post-speech phase.

  13. Inverted U-Shaped Dose-Response Curve of the Anxiolytic Effect of Cannabidiol during Public Speaking in Real Life.

    Science.gov (United States)

    Zuardi, Antonio W; Rodrigues, Natália P; Silva, Angélica L; Bernardo, Sandra A; Hallak, Jaime E C; Guimarães, Francisco S; Crippa, José A S

    2017-01-01

    The purpose of this study was to investigate whether the anxiolytic effect of cannabidiol (CBD) in humans follows the same pattern of an inverted U-shaped dose-effect curve observed in many animal studies. Sixty healthy subjects of both sexes aged between 18 and 35 years were randomly assigned to five groups that received placebo, clonazepam (1 mg), and CBD (100, 300, and 900 mg). The subjects were underwent a test of public speaking in a real situation (TPSRS) where each subject had to speak in front of a group formed by the remaining participants. Each subject completed the anxiety and sedation factors of the Visual Analog Mood Scale and had their blood pressure and heart rate recorded. These measures were obtained in five experimental sessions with 12 volunteers each. Each session had four steps at the following times (minutes) after administration of the drug/placebo, as time 0: -5 (baseline), 80 (pre-test), 153 (speech), and 216 (post-speech). Repeated-measures analyses of variance showed that the TPSRS increased the subjective measures of anxiety, heart rate, and blood pressure. Student-Newman-Keuls test comparisons among the groups in each phase showed significant attenuation in anxiety scores relative to the placebo group in the group treated with clonazepam during the speech phase, and in the clonazepam and CBD 300 mg groups in the post-speech phase. Clonazepam was more sedative than CBD 300 and 900 mg and induced a smaller increase in systolic and diastolic blood pressure than CBD 300 mg. The results confirmed that the acute administration of CBD induced anxiolytic effects with a dose-dependent inverted U-shaped curve in healthy subjects, since the subjective anxiety measures were reduced with CBD 300 mg, but not with CBD 100 and 900 mg, in the post-speech phase.

  14. Long-term prognosis in an ST-segment elevation myocardial infarction population treated with routine primary percutaneous coronary intervention: from clinical trial to real-life experience

    DEFF Research Database (Denmark)

    Pedersen, Sune; Galatius, Soren; Mogelvang, Rasmus;

    2009-01-01

    BACKGROUND: We sought to describe the long-term prognosis after routine primary percutaneous coronary intervention (pPCI) in a contemporary consecutive population of patients with presumed ST-segment elevation myocardial infarction, compare it with similar results from the landmark DANAMI-2 trial...... trial reached the combined end point of death, reinfarction, or stroke (P=0.68), whereas the all-cause mortality was 13.0% and 13.7%, respectively (P=0.65). Patients admitted during off hours had the same risk of reaching the combined end point of death, reinfarction, or stroke compared with patients......). Furthermore, the long-term prognosis was the same regardless of whether the pPCI was performed during off hours or office hours. Thus, pPCI including transportation of patients from noninvasive centers can be applied successfully in a real-life population....

  15. What is the best model for girls and boys faced with a standardized mathematics evaluation situation: a hardworking role model or a gifted role model?

    Science.gov (United States)

    Bagès, Céline; Martinot, Delphine

    2011-09-01

    Same-gender role models are likely to improve girls' math performance. This field experiment examined whether the explanation given for a role model's success also influence children's math performance. Fifth graders were presented with a female or a male role model before a difficult math test and were informed about the cause of his/her math success (effort vs. ability vs. no explanation). The results showed that the gender of a hardworking role model did not influence math performance. In contrast, when the role model's success was not explained or explained by abilities, children performed better with the female role model than with the male role model. The hardworking role model and the female role model allowed reducing stereotype threat among girls.

  16. Differences between clinical "snap-shot" and "real-life" assessments of lumbar spine alignment and motion - What is the "real" lumbar lordosis of a human being?

    Science.gov (United States)

    Dreischarf, Marcel; Pries, Esther; Bashkuev, Maxim; Putzier, Michael; Schmidt, Hendrik

    2016-03-21

    The individual lumbar lordosis and lumbar motion have been identified to play an important role in pathogenesis of low back pain and are essential references for preoperative planning and postoperative evaluation. The clinical "gold-standard" for measuring lumbar lordosis and its motion are radiological "snap-shots" taken while standing and during upper-body flexion and extension. The extent to which these clinically assessed values characterise lumbar alignment and its motion in daily life merits discussion. A non-invasive measurement-system was employed to measure lumbar lordosis and lumbar motion in 208 volunteers (age: 20-74yrs; ♀/♂: 115/93). For an initial short-term measurement, comparable with the clinical "snap-shot", lumbar lordosis and its motion were assessed while standing and during flexion and extension. Subsequently, volunteers were released to their daily lives while wearing the device, and measurements were performed during the following 24h. The average lumbar lordosis during 24h (8.0°) differed significantly from the standardised measurement while standing (33.3°). Ranges of motion were significantly different throughout the day compared to standing measurements. The influence of the factors age and gender on lordosis and its motion resulted in conflicting results between long- and short-term-measurements. In conclusion, results of short-term examinations differ considerably from the average values during real-life. These findings might be important for surgical planning and increase the awareness of the biomechanical challenges that spinal structures and implants face in real-life. Furthermore, long-term assessments of spinal alignment and motion during daily life can provide valid data on spinal function and can reveal the importance of influential factors. Copyright © 2016 Elsevier Ltd. All rights reserved.

  17. Bacteriotherapy with Streptococcus salivarius 24SMB and Streptococcus oralis 89a nasal spray for preventing recurrent acute otitis media in children: a real-life clinical experience

    Directory of Open Access Journals (Sweden)

    La Mantia I

    2017-06-01

    Full Text Available Ignazio La Mantia, Attilio Varricchio, Giorgio Ciprandi Associazione Italiana Vie Aeree Superiori, Naples, Italy Abstract: Recurrence of acute otitis media (RAOM is a relevant issue in the clinical practice. “Bacteriotherapy” has been proposed as an option in children with RAOM. Streptococcus salivarius 24SMB nasal spray has been previously demonstrated to reduce the risk of acute otitis media (AOM in otitis-prone children. The current retrospective and observational study aimed to confirm this outcome in a real-life setting, such as the common pediatric practice. Group A (108 children served as control; group B (159 children was treated with S. salivarius 24SMB and Streptococcus oralis 89a nasal spray after the first AOM episode. Active treatment consisted of 3 monthly courses: 2 puffs per nostril twice/day for a week. Group B showed a significant reduction of AOM episodes in comparison with group A (p<0.0001. Notably, all actively treated children with the highest AOM recurrence had a reduction of recurrence, whereas only 50% of the control group children had reduced RAOM (p<0.0001. Also, severity grade of AOM significantly diminished after the preventive bacteriotherapy (p<0.0001. In conclusion, the current retrospective and observational study demonstrated that S. salivarius 24SMB and S. oralis 89a nasal spray could be effective in the prevention of RAOM in a real-life setting. Keywords: recurrent acute otitis media, bacteriotherapy, Streptococcus salivarius 24SMB, Streptococcus oralis 89a, nasal spray, children

  18. Does teaching of documentation of shoulder dystocia delivery through simulation result in improved documentation in real life?

    Science.gov (United States)

    Comeau, Robyn; Craig, Catherine

    2014-03-01

    Objectif : La documentation des accouchements compliqués par une dystocie de l’épaule constitue une compétence communicationnelle précieuse que les résidents doivent chercher à maîtriser au cours de leur formation. Nous avions pour objectif de déterminer si l’enseignement de la documentation de la dystocie de l’épaule dans le cadre d’une simulation se traduisait en une amélioration de la documentation d’un tel événement dans le cadre d’une situation clinique réelle. Méthodes : Nous avons mené, entre novembre 2010 et décembre 2012, une étude de cohorte portant sur des résidents en obstétrique-gynécologie qui en étaient rendus à la 2e, 3e, 4e ou 5e année de leur formation. Chacun de ces résidents a participé à une séance de simulation de la dystocie de l’épaule; à cette occasion, nous leur avons demandé de rédiger une note sur l’accouchement immédiatement à la suite de la séance de simulation. Des commentaires leur ont été offerts quant à leur rendement au cours de l’accouchement et à leur documentation des événements. Par la suite, les dossiers dictés liés aux accouchements compliqués par une dystocie de l’épaule ayant eu lieu immédiatement avant et après la séance de simulation ont été récupérés dans le système Meditech. Une liste de vérification détaillée a été utilisée pour évaluer la qualité de la documentation dictée par les résidents avant et après la séance de simulation. Résultats : Tous les résidents admissibles (18) se sont inscrits à l’étude et 17 d’entre eux ont répondu aux critères d’inclusion. Dix résidents (59 %) avaient procédé à la documentation d’un accouchement compliqué par une dystocie de l’épaule avant et après la séance de simulation, cinq résidents (29 %) n’avaient procédé à une telle documentation qu’avant la séance et deux résidents (18 %) ne l’avaient fait qu’après la séance. Lorsque l’évaluation a port

  19. Development and evaluation of SOA-based AAL services in real-life environments: a case study and lessons learned.

    Science.gov (United States)

    Stav, Erlend; Walderhaug, Ståle; Mikalsen, Marius; Hanke, Sten; Benc, Ivan

    2013-11-01

    The proper use of ICT services can support seniors in living independently longer. While such services are starting to emerge, current proprietary solutions are often expensive, covering only isolated parts of seniors' needs, and lack support for sharing information between services and between users. For developers, the challenge is that it is complex and time consuming to develop high quality, interoperable services, and new techniques are needed to simplify the development and reduce the development costs. This paper provides the complete view of the experiences gained in the MPOWER project with respect to using model-driven development (MDD) techniques for Service Oriented Architecture (SOA) system development in the Ambient Assisted Living (AAL) domain. To address this challenge, the approach of the European research project MPOWER (2006-2009) was to investigate and record the user needs, define a set of reusable software services based on these needs, and then implement pilot systems using these services. Further, a model-driven toolchain covering key development phases was developed to support software developers through this process. Evaluations were conducted both on the technical artefacts (methodology and tools), and on end user experience from using the pilot systems in trial sites. The outcome of the work on the user needs is a knowledge base recorded as a Unified Modeling Language (UML) model. This comprehensive model describes actors, use cases, and features derived from these. The model further includes the design of a set of software services, including full trace information back to the features and use cases motivating their design. Based on the model, the services were implemented for use in Service Oriented Architecture (SOA) systems, and are publicly available as open source software. The services were successfully used in the realization of two pilot applications. There is therefore a direct and traceable link from the user needs of the

  20. Contextual Development: Situating the Social Change Model of Leadership Development within a Broader Reality of Comprehensive Support

    Science.gov (United States)

    Whitten-Andrews, Jeanie

    2016-01-01

    The social change model has proven an effective and widely utilized model assisting college students in leadership development toward positive social change. However, while this particular model gives much needed attention to the process of development leading to social change, it fails to acknowledge the external factors which significantly…

  1. Method of Situation Recognition Based on Hidden Markov Model%一种基于HMM的场景识别方法

    Institute of Scientific and Technical Information of China (English)

    何彦斌; 杨志义; 马荟; 王海鹏; 於志文

    2011-01-01

    隐马尔科夫模型[1]作为一种统计分析模型,能够通过观测向量序列计算其隐含状态的概率分布密度.提出一种智能空间中基于HMM的场景识别方法,该方法指定系统相关情境信息,确定隐含场景集和观察情境集,采用部分相关情境信息而非全部情境信息作为场景特征参与场景识别,利用HMM对隐含场景间的关系进行建模,设计了基于HMM的场景识别算法.实验结果表明,采用基于HMM的场景识别方法能够获得较高的识别效率.%Hidden Markov Model,as a statistical model,can get the probability of hidden status by calculating the sequence of observed status. In this paper,a recognition approach based on HMM was proposed to infer situation in smart space. The approach infers situation by calculating partly contexts of system-related, using HMM to model the hidden situations. We designed the recognition algorithm based on HMM. Our experimental results show that this method can make a good performs and get a higher efficiency.

  2. Agoraphobia: A Situational Analysis.

    Science.gov (United States)

    Sinnott, Austin; And Others

    1981-01-01

    Agoraphobia patients answered a questionnaire describing anxiety-producing situations. Home environment was associated with supportive company. Situations requiring patients to venture out alone were most anxiety-producing. The overriding importance of a significant other suggests treatment implications. (JAC)

  3. Current situation and reflection of domestic intravenous pharmacy admixture models%国内静脉药物调配模式现状与思考

    Institute of Scientific and Technical Information of China (English)

    夏英华; 毛燕君; 朱建英

    2012-01-01

    This article summarized the current situation of three intravenous pharmacy admixture models,including ward intravenous drag distribution model, Pharmacy Intravenous Admixture Services (PIVAS) and decentralized distribution model. It analyzed the advantages and disadvantages,and on the basis,reflection and suggestions of pharmacy admixture methods were put forward.%文章分别归纳了国内病区药物自配模式、静脉药物集中调配模式和分散药物调配模式的发展现状及其优缺点,在此基础上,对国内静脉药物调配模式的发展进行思考并提出建议.

  4. Situated Entrepreneurial Cognition

    OpenAIRE

    Dew, Nicholas; Grichnik, Dietmar; Mayer-Haug, Katrin; Read, Stuart; Brinckmann, Jan

    2014-01-01

    The article of record as published may be located at http://dx.doi.org/10.1111/ijmr.12051 This paper reviews and integrates research from both within and outside the entrepreneurship field under the label of ‘situated cognition’. Situated cognition is the notion that cognitive activity inherently involves perception and action in the context of a human body situated in a real-world environment. The review concentrates on three areas of the situated cognition literature that hav...

  5. Report: the current situation of sanitary landfills in Brazil and the importance of the application of economic models.

    Science.gov (United States)

    Neto, Raul Oliveira; Petter, Carlos Otávio; Cortina, José Luis

    2009-12-01

    We present the development stage of the sanitary landfills in Brazil in the context of urban solid residue management, demonstrating the necessity and importance of the employment of economic models. In the article, a cost estimate model is proposed as the basis for studies to be applied by sector management, including the city council, companies, consultants and engineers, contributing to the choice of new areas, public bids, municipal consortia and private public partnerships.

  6. Report: the current situation of sanitary landfills in Brazil and the importance of the application of economic models

    OpenAIRE

    Oliveira Neto, Raúl; Otávio Petter, Carlos; Cortina Pallás, José Luís

    2009-01-01

    We present the development stage of the sanitary landfills in Brazil in the context of urban solid residue management, demonstrating the necessity and importance of the employment of economic models. In the article, a cost estimate model is proposed as the basis for studies to be applied by sector management, including the city council, companies, consultants and engineers, contributing to the choice of new areas, public bids, municipal consortia and private public partnerships. Peer Re...

  7. Probabilistic risk analysis in manufacturing situational operation: application of modelling techniques and causal structure to improve safety performance.

    Directory of Open Access Journals (Sweden)

    Jose Cristiano Pereira

    2015-01-01

    Full Text Available The use of probabilistic risk analysis in jet engines manufacturing process is essential to prevent failure. The objective of this study is to present a probabilistic risk analysis model to analyze the safety of this process. The standard risk assessment normally conducted is inadequate to address the risks. To remedy this problem, the model presented in this paper considers the effects of human, software and calibration reliability in the process. Bayesian Belief Network coupled to a Bow Tie diagram is used to identify potential engine failure scenarios. In this context and to meet this objective, an in depth literature research was conducted to identify the most appropriate modeling techniques and an interview were conducted with experts. As a result of this study, this paper presents a model that combines fault tree analysis, event tree analysis and a Bayesian Belief Networks into a single model that can be used by decision makers to identify critical risk factors in order to allocate resources to improve the safety of the system. The model is delivered in the form of a computer assisted decision tool supported by subject expert estimates.

  8. Continuous up to 4 Years Entecavir Treatment of HBV-Infected Adolescents - A Longitudinal Study in Real Life.

    Science.gov (United States)

    Pawłowska, Małgorzata; Domagalski, Krzysztof; Smok, Beata; Rajewski, Paweł; Wietlicka-Piszcz, Magdalena; Halota, Waldemar; Tretyn, Andrzej

    This study evaluated the long-term (up to 4 years) efficacy and safety of entecavir ETV treatment and analysed the significance of baseline and on-treatment factors in long-term ETV outcomes in adolescents with chronic hepatitis B (CHB). We determined the cumulative virological and serological outcomes of 44 adolescents with CHB receiving ETV for up to 4 years. To investigate the dynamics of HBV DNA, ALT activity and hepatitis B e antigen (HBeAg) seroconversion over time and their associations with the considered factors, generalized estimating equation (GEE) models were used. The cumulative rates of undetectable HBV DNA (<20 IU/ml) and HBeAg seroconversion after 4 years were 89.7% and 55.4%, respectively. In the study group, we showed that having undetectable HBV DNA at the 6th or 12th month of therapy predicted the achievement of a sustained response rate (SRR, defined as the loss of HBV DNA, loss of HBeAg and ALT normalization) at year 3 of ETV therapy (P = 0.048, OR = 5.83; P = 0.012; OR = 14.57, respectively). The GEE analysis indicated that of the different factors, the duration of ETV therapy had a strong impact on the achievement of virological suppression, HBeAg seroconversion and SRR in adolescents. Each month after the initiation of therapy, the odds of loss of HBV DNA increased by approximately 5% (OR = 1.05, P<0.0001), on average. Additionally, the GEE analysis revealed that adolescents with an age at infection of ≥10 years had 3 times higher odds of achieving undetectable HBV DNA than patients with a younger infection age (OR = 3.67, P = 0.028). None of the ETV-treated patients reported significant adverse effects. ETV is an effective and safe treatment option for adolescents with CHB. Undetectable HBV DNA in the 6th and/or 12th month of ETV treatment and older age at infection could predict maintained virological suppression.

  9. Continuous up to 4 Years Entecavir Treatment of HBV-Infected Adolescents – A Longitudinal Study in Real Life

    Science.gov (United States)

    Pawłowska, Małgorzata; Smok, Beata; Rajewski, Paweł; Wietlicka-Piszcz, Magdalena; Halota, Waldemar; Tretyn, Andrzej

    2016-01-01

    This study evaluated the long-term (up to 4 years) efficacy and safety of entecavir ETV treatment and analysed the significance of baseline and on-treatment factors in long-term ETV outcomes in adolescents with chronic hepatitis B (CHB). We determined the cumulative virological and serological outcomes of 44 adolescents with CHB receiving ETV for up to 4 years. To investigate the dynamics of HBV DNA, ALT activity and hepatitis B e antigen (HBeAg) seroconversion over time and their associations with the considered factors, generalized estimating equation (GEE) models were used. The cumulative rates of undetectable HBV DNA (<20 IU/ml) and HBeAg seroconversion after 4 years were 89.7% and 55.4%, respectively. In the study group, we showed that having undetectable HBV DNA at the 6th or 12th month of therapy predicted the achievement of a sustained response rate (SRR, defined as the loss of HBV DNA, loss of HBeAg and ALT normalization) at year 3 of ETV therapy (P = 0.048, OR = 5.83; P = 0.012; OR = 14.57, respectively). The GEE analysis indicated that of the different factors, the duration of ETV therapy had a strong impact on the achievement of virological suppression, HBeAg seroconversion and SRR in adolescents. Each month after the initiation of therapy, the odds of loss of HBV DNA increased by approximately 5% (OR = 1.05, P<0.0001), on average. Additionally, the GEE analysis revealed that adolescents with an age at infection of ≥10 years had 3 times higher odds of achieving undetectable HBV DNA than patients with a younger infection age (OR = 3.67, P = 0.028). None of the ETV-treated patients reported significant adverse effects. ETV is an effective and safe treatment option for adolescents with CHB. Undetectable HBV DNA in the 6th and/or 12th month of ETV treatment and older age at infection could predict maintained virological suppression. PMID:27685782

  10. 文本阅读中情境模型时间维度研究%Temporal Dimension Research of Situation Model in Narrative Text Comprehension

    Institute of Scientific and Technical Information of China (English)

    郭艳彪; 陈琳; 夏天生; 莫雷

    2014-01-01

    情境模型时间维度研究是目前文本阅读研究的热点之一。研究者们从不同角度、采用不同范式和技术手段证明了时间维度在情境模型建构中的重要作用,并且在这方面也取得了大量研究成果。文章从理论观点和实证研究两方面对这些研究成果进行梳理和总结,并对未来研究发展做出了展望。%Temporal information is one of the important dimensions of the situation model in narrative text comprehension, as well as one of the hot topics in current studies.The researchers proved the important role of temporal dimension in the situation model, through different angles, paradigms and technological means, and gained a lot of research results in the domain.This paper reviewed previous researches, and summarized these research results from aca-demic views and empirical researches, meanwhile, made the prospects about future researches and development.

  11. Updating the Spatial Situation Model: Effects of Cognitive Style%空间情境模型的更新:认知方式的影响

    Institute of Scientific and Technical Information of China (English)

    何先友; 杨惠; 李惠娟; 魏玉兵; Danielle McNamara

    2011-01-01

    采用前照应解决(anaphora resolution)与学习探测相结合的实验范式以及移动窗口技术探讨不同认知方式个体的空间情境模型更新能力的差异.实验1发现,场依存性被试在高预见性条件下表现出空间距离效应,低预见性条件下则没有;而场独立性被试刚好相反.实验2通过在关键句中提示路径房间的一个物品深入探讨更新过程中不同认知方式个体更新模式的差异,结果发现,两类被试在低预见性记叙文中都表现出了明显的空间距离效应.这表明,场独立性个体的空间情境模型更新能力高于场依存性个体的更新能力.%Text comprehension researchers generally agree that successful understanding of narrative text requires building a coherent situation model, and this process is affected by many factors, including text materials, prior knowledge, and individual processing abilities. Past research indicates that working memory is related to information processing but less so with situation model construction. Nonetheless, there is some evidence that visuospatial and verbal working memory subcomponents of working memory influence situation model updating processes. In addition, individuals' cognitive styles may be correlated with working memory, especially visuospatial memory and the central executive. For example, visually field-independent participants have higher levels of psychological differentiation, cognitive reorganization, visuospatial memory, and verbal working memory than do field-dependent participants. The question addressed in this study is whether cognitive style is related to situation model construction.Two experiments were conducted to explore this question using the anaphora resolution paradigm and moving window technique. Participants' field dependency was assessed using the Embedded Figures Test. Among 134 university students, 80 participants were included who were the top and bottom 30% in terms offield dependency

  12. 5-grass pollen tablets achieve disease control in patients with seasonal allergic rhinitis unresponsive to drugs: a real-life study

    Directory of Open Access Journals (Sweden)

    Pastorello EA

    2013-12-01

    Full Text Available Elide Anna Pastorello,1 Laura Losappio,1 Stefania Milani,2 Giuseppina Manzotti,3 Valentina Fanelli,4 Valerio Pravettoni,5 Fabio Agostinis,6 Alberto Flores D’Arcais,7 Ilaria Dell'Albani,8 Paola Puccinelli,9 Cristoforo Incorvaia,10 Franco Frati81Allergy and Immunology Department, Niguarda Hospital, Milan, 2Allergy Department, San Marco General Hospital, Bergamo, 3Allergy Department, Treviglio Hospital, Bergamo, 4Allergy Department, Italian Institute for Auxology, Milan, 5Clinical Allergy and Immunology Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, 6Department of Pediatrics, Riuniti Hospital, Bergamo, 7Department of Pediatrics, Legnano Hospital, Milan, 8Medical and Scientific Department, Stallergenes Italy, Milan, 9Regulatory Department, Stallergenes Italy, Milan, 10Allergy/Pulmonary Rehabilitation, ICP Hospital, Milan, ItalyBackground: An important subpopulation in allergic rhinitis is represented by patients with severe form of disease that is not responsive to drug treatment. It has been reported that grass pollen subcutaneous immunotherapy is effective in drug-resistant patients. In a real-life study, we evaluated the efficacy of 5-grass pollen tablets in patients with grass pollen-induced allergic rhinitis not responsive to drug therapy.Methods: We carried out this multicenter observational study in adults and adolescents with grass-induced allergic rhinitis not responsive to drug therapy who were treated for a year with 5-grass pollen tablets. Clinical data collected before and after sublingual immunotherapy (SLIT included Allergic Rhinitis and its Impact on Asthma (ARIA classification of allergic rhinitis, response to therapy, and patient satisfaction.Results: Forty-seven patients entered the study. By ARIA classification, three patients had moderate to severe intermittent allergic rhinitis, ten had mild persistent allergic rhinitis, and 34 had moderate to severe persistent allergic rhinitis. There were no cases

  13. Real-life treatment of acute exacerbations of chronic bronchitis with moxifloxacin or macrolides: a comparative post-marketing surveillance study in general practice.

    Science.gov (United States)

    Schaberg, T; Möller, M; File, T; Stauch, K; Landen, H

    2006-01-01

    To compare the real-life treatment of acute exacerbations of chronic bronchitis (AECBs) using moxifloxacin tablets or one of the oral macrolides azithromycin, clarithromycin or roxithromycin in terms of symptom relief, time until improvement and cure, overall efficacy and tolerability. This prospective, non-interventional, multicentre study included out-patients with AECB whose last exacerbation was treated with a macrolide. The current AECB was treated either with moxifloxacin or with one of the macrolides azithromycin, clarithromycin or roxithromycin. Data were obtained on the patient's characteristics, disease and treatment history, the course of the current AECB including time to improvement and cure, and the final assessments of efficacy and tolerability. All adverse events were recorded in patients treated with moxifloxacin; for patients receiving macrolides, only drug-related adverse events were reported. 464 physicians treated 904 patients with moxifloxacin and 846 patients with one of the macrolides. Age, sex and body mass index were well matched between the two treatment groups. However, more moxifloxacin than macrolide patients presented with a generally bad condition (62.8% vs 48.6%). About 42% of patients in both groups had had chronic bronchitis for 1-5 years, and about 27% for 5-10 years. The mean number of AECBs in the previous 12 months was 2.7 and 2.6, respectively. Moxifloxacin was administered to most patients for 5 (43.8%) or 7 days (42.4%). Patients in the macrolide group were treated in most cases with clarithromycin 500 mg for 4-7 days, roxithromycin 300 mg for 6-7 days or azithromycin 500 mg for 3 days. Physicians assessed overall efficacy and tolerability as 'very good' or 'good' in 96.1% and 98.1%, respectively, of moxifloxacin-treated patients and in 67.5% and 91.7%, respectively, of macrolide-treated patients. The mean duration until improvement and cure of AECB was 3.2 days (+/- SD 1.5) and 6.2 days (+/- 2.6) in moxifloxacin

  14. Real-life efficacy of pregabalin for the treatment of peripheral neuropathic pain in daily clinical practice in Denmark: the NEP-TUNE study

    Directory of Open Access Journals (Sweden)

    Crawford ME

    2016-05-01

    Full Text Available Michael E Crawford,1 Peter Bo Poulsen,2 Berit Schiøttz-Christensen,3 Andreas Habicht,4 Mette Strand,2 Flemming W Bach5 1Copenhagen City Pain Clinic, Copenhagen K, 2Pfizer Denmark ApS, Ballerup, 3Spine Center Southern Denmark, Lillebælt Hospital, Middelfart, 4Signifikans ApS, Vedbæk, 5Department of Neurology, Aalborg University Hospital, Aalborg, Denmark Objective: The aim of this study was to provide evidence regarding the real-life efficacy of pregabalin in the treatment of peripheral neuropathic pain (NeP in Denmark. Methods: In this prospective, observational, noninterventional study, pregabalin (Lyrica® was prescribed following usual clinical practice. Compared with baseline, the primary study end points after 3 months of observation were changes in 1 the average level of pain during the past week, 2 the worst level of pain during the past week, and 3 the least level of pain during the past week. The Wilcoxon signed-rank test was used to perform paired analyses, and a multivariate regression analysis investigated factors driving change in pain. Results: A total of 86 of the 128 patients included were regarded as efficacy evaluable (those completing 3 months of pregabalin treatment. Patients (59 years were long-time sufferers of peripheral NeP, and 38% of them had comorbidities. The majority had previously been treated with tricyclic antidepressants or gabapentin. The average dose of pregabalin was 81.5 mg/d at baseline and 240 mg/d after 3 months. A clinically and statistically significant improvement of 2.2 points in the average level of pain intensity was found after 3 months. The higher the pain intensity at baseline, the higher was the reduction of the pain score. Positive results were also found for pain-related sleep interference, patients’ global impression of change, quality of life, and work and productivity impairment. Twenty-one patients reported 28 adverse events. Conclusion: This real-life study indicates that for some

  15. The Updating of Situation Model:Further Evidence of Event Frame-Dependent Hypothesis%情境模型的更新:事件框架依赖假设的进一步证据

    Institute of Scientific and Technical Information of China (English)

    赵雪汝; 何先友; 赵婷婷; 杨惠兰; 林席明; 张维

    2014-01-01

    采用多指标探测范式,从客体信息以及活动信息的角度出发,考察事件框架内外时间、空间转换对情境模型更新的影响。结果发现:在事件框架内,维度转换并不是情境模型更新的充分条件,时间转换与终止的活动信息相结合引起情境模型的快速更新,而空间转换与移除的客体信息相结合引起情境模型的快速更新;在事件框架外,维度转换是情境模型更新的充分条件,维度转换会引起情境模型的更新。研究丰富了事件框架依赖假设。%When comprehending narrative text, a reader forms situation models that represent occurring events. As events unfold in the text, the reader must update his or her situation model, or mental representation. Zwaan, Langston and Graesser (1995) suggested that the event is the core unit in constructing the mental representation of narrative reading. The reader establishes the mental representation of events by tracking in five dimensions:time, space, characters, causality and target. If any one of the five dimensions changes, the situation model requires updating. The temporal and spatial dimensions were the focus of the current study. A large number of studies have shown that both play important roles in constructing the situation model, yet it remains unclear whether a change in time or space is a sufficient condition for situational model updating. Xia et al. (2013) found that space shift and event shift had a close relationship. However, they did not find the combination of space shift and removing objects caused the updating of spatial situation model. He et al. (2013) further proposed and tested the Event Frame-Dependent Hypothesis to explore the effect of time shift on the updating of situation model. Results of their study confirmed the hypothesis. However, because differences between the updating of the temporal situation model and the updating of spatial situational model were not found

  16. Computer modelling for risk assessment of emergency situations and terrorist attacks during transportation using methods of fuzzy set theory

    Energy Technology Data Exchange (ETDEWEB)

    Kosterev, V.V.; Boliatko, V.V.; Gusev, S.M.; Panin, M.P. [MEPhI, Moscow (Russian Federation); Averkin, A.N. [CC RAS, Moscox (Russian Federation)

    1998-07-01

    Computer software for risk assessment of transportation of important freight has been developed. It incorporates models of transport accidents, including terrorist attacks. These models use, among the others, input data of cartographic character. Geographic information system technology and electronic maps of a geographic area are involved as an instrument for handling this kind of data. Fuzzy set theory methods as well as standard methods of probability theory have been used for quantitative risk assessment. Fuzzy algebraic operations and their computer realization are discussed. Risk assessment for one particular route of railway transportation is given as an example. (author)

  17. A DYNAMIC MIXED MODEL WITH NITROGEN LEACHING LOSSES FROM THE PONDED PADDY RICE FIELD UNDER SITUATION OF BURIED PIPE DRAINAGE

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    In order to study the law of nitrogen leaching losses from the paddy field under the condition of drainage, based on the theories of potential energy and solute transport, a water-nitrogen dynamic mixed model by combining the flow net with dynamic method was established. In the computation of buried pipe drainage, the superposition principle was used to simplify the complex solving of the two-dimensional problem about water-nitrogen transportation in Soil-Plant-Air-Continuous (SPAC) system into several one-dimensional problems. The presented method is simple and practical. Some field experiments were carried out to demonstrate the validity of the model.

  18. Cultural Models of Teaching and Learning in Math and Science: Exploring the Intersections of Culture, Cognition, and Pedagogical Situations

    Science.gov (United States)

    Ferrare, Joseph J.; Hora, Matthew T.

    2014-01-01

    While researchers have examined how disciplinary and departmental cultures influence instructional practices in higher education, there has yet to be an examination of this relationship at the embodied level of culture. In this article we utilize cultural models theory to examine the theories of student learning and teaching practice espoused and…

  19. In-vehicle and site-based observations of vehicles and cyclists : a small-scale ND study in The Netherlands. PROmoting real Life Observations for Gaining Understanding of road user behaviour in Europe PROLOGUE, Deliverable D3.4

    NARCIS (Netherlands)

    Christoph, M. Nes, N. van Pauwelussen, J. Mansvelders, R. Horst, A.R.A. van der & Hoedemaeker, M.

    2011-01-01

    The main objective of the project PROLOGUE (PROmoting real Life Observations for Gaining Understanding of road user behaviour in Europe) is to explore the feasibility and usefulness of a large-scale European naturalistic driving observation study. The work described in this deliverable focused on th

  20. Nonlinear spectro-temporal features based on a cochlear model for automatic speech recognition in a noisy situation.

    Science.gov (United States)

    Choi, Yong-Sun; Lee, Soo-Young

    2013-09-01

    A nonlinear speech feature extraction algorithm was developed by modeling human cochlear functions, and demonstrated as a noise-robust front-end for speech recognition systems. The algorithm was based on a model of the Organ of Corti in the human cochlea with such features as such as basilar membrane (BM), outer hair cells (OHCs), and inner hair cells (IHCs). Frequency-dependent nonlinear compression and amplification of OHCs were modeled by lateral inhibition to enhance spectral contrasts. In particular, the compression coefficients had frequency dependency based on the psychoacoustic evidence. Spectral subtraction and temporal adaptation were applied in the time-frame domain. With long-term and short-term adaptation characteristics, these factors remove stationary or slowly varying components and amplify the temporal changes such as onset or offset. The proposed features were evaluated with a noisy speech database and showed better performance than the baseline methods such as mel-frequency cepstral coefficients (MFCCs) and RASTA-PLP in unknown noisy conditions.