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Sample records for model promotes articulation

  1. CONSIDERATIONS UPON CONTACT STRESS MODELLING IN DENTAL ARTICULATOR PAIRS

    Directory of Open Access Journals (Sweden)

    Carmen Ciornei

    2012-05-01

    Full Text Available A dental articulator is a mechanism which simulates the temporo-mandibular joint. The articulator is essential as it replicates the basic motions of the upper and lower mandibles, both revolve and translational motions. In the present paper the stresses from an articulator TMJ modelled as a bronze sphere into a cylindrical steel cavity are analyzed by two methods, first applying the Hertzian contact theory and then numerically, by means of finite element analysis using the simulation module in CATIA.

  2. Software systems for modeling articulated figures

    Science.gov (United States)

    Phillips, Cary B.

    1989-01-01

    Research in computer animation and simulation of human task performance requires sophisticated geometric modeling and user interface tools. The software for a research environment should present the programmer with a powerful but flexible substrate of facilities for displaying and manipulating geometric objects, yet insure that future tools have a consistent and friendly user interface. Jack is a system which provides a flexible and extensible programmer and user interface for displaying and manipulating complex geometric figures, particularly human figures in a 3D working environment. It is a basic software framework for high-performance Silicon Graphics IRIS workstations for modeling and manipulating geometric objects in a general but powerful way. It provides a consistent and user-friendly interface across various applications in computer animation and simulation of human task performance. Currently, Jack provides input and control for applications including lighting specification and image rendering, anthropometric modeling, figure positioning, inverse kinematics, dynamic simulation, and keyframe animation.

  3. Modeling, Simulation and Position Control of 3DOF Articulated Manipulator

    Directory of Open Access Journals (Sweden)

    Hossein Sadegh Lafmejani

    2014-08-01

    Full Text Available In this paper, the modeling, simulation and control of 3 degrees of freedom articulated robotic manipulator have been studied. First, we extracted kinematics and dynamics equations of the mentioned manipulator by using the Lagrange method. In order to validate the analytical model of the manipulator we compared the model simulated in the simulation environment of Matlab with the model was simulated with the SimMechanics toolbox. A sample path has been designed for analyzing the tracking subject. The system has been linearized with feedback linearization and then a PID controller was applied to track a reference trajectory. Finally, the control results have been compared with a nonlinear PID controller.

  4. Promoting Models

    Science.gov (United States)

    Li, Qin; Zhao, Yongxin; Wu, Xiaofeng; Liu, Si

    There can be multitudinous models specifying aspects of the same system. Each model has a bias towards one aspect. These models often override in specific aspects though they have different expressions. A specification written in one model can be refined by introducing additional information from other models. The paper proposes a concept of promoting models which is a methodology to obtain refinements with support from cooperating models. It refines a primary model by integrating the information from a secondary model. The promotion principle is not merely an academic point, but also a reliable and robust engineering technique which can be used to develop software and hardware systems. It can also check the consistency between two specifications from different models. A case of modeling a simple online shopping system with the cooperation of the guarded design model and CSP model illustrates the practicability of the promotion principle.

  5. Articulated registration: elastic registration based on a wire-model

    Science.gov (United States)

    Martin-Fernandez, Miguel A.; Munyoz-Moreno, Emma; Martin-Fernandez, Marcos; Alberola-Lopez, Carlos

    2005-04-01

    In this paper we propose a new method of elastic registration of anatomical structures that bears an inner skeleton, such as the knee, hand or spine. Such a method has to deal with great degrees of variability, specially for the case of inter-subject registration; but even for the intra-subject case the degree of variability of images will be large since the structures we bear in mind are articulated. Rigid registration methods are clearly inappropriate for this problem, and well-known elastic methods do not usually incorporate the restriction of maintaining long skeletal structures straight. A new method is therefore needed to deal with such a situation; we call this new method "articulated registration". The inner bone skeleton is modeled with a wire model, where wires are drawn by connecting landmarks located in the main joints of the skeletal structure to be registered (long bones). The main feature of our registration method is that within the bone axis (specifically, where the wires are) an exact registration is guaranteed, while for the remaining image points an elastic registration is carried out based on a distance transform (with respect to the model wires); this causes the registration on long bones to be affine to all practical purposes, while the registration of soft tissue -- far from the bones -- is elastic. As a proof-of-concept of this method we describe the registration of hands on radiographs.

  6. Beyond the functional matrix hypothesis: a network null model of human skull growth for the formation of bone articulations.

    Science.gov (United States)

    Esteve-Altava, Borja; Rasskin-Gutman, Diego

    2014-09-01

    Craniofacial sutures and synchondroses form the boundaries among bones in the human skull, providing functional, developmental and evolutionary information. Bone articulations in the skull arise due to interactions between genetic regulatory mechanisms and epigenetic factors such as functional matrices (soft tissues and cranial cavities), which mediate bone growth. These matrices are largely acknowledged for their influence on shaping the bones of the skull; however, it is not fully understood to what extent functional matrices mediate the formation of bone articulations. Aiming to identify whether or not functional matrices are key developmental factors guiding the formation of bone articulations, we have built a network null model of the skull that simulates unconstrained bone growth. This null model predicts bone articulations that arise due to a process of bone growth that is uniform in rate, direction and timing. By comparing predicted articulations with the actual bone articulations of the human skull, we have identified which boundaries specifically need the presence of functional matrices for their formation. We show that functional matrices are necessary to connect facial bones, whereas an unconstrained bone growth is sufficient to connect non-facial bones. This finding challenges the role of the brain in the formation of boundaries between bones in the braincase without neglecting its effect on skull shape. Ultimately, our null model suggests where to look for modified developmental mechanisms promoting changes in bone growth patterns that could affect the development and evolution of the head skeleton. © 2014 Anatomical Society.

  7. Inferring 3D Articulated Models for Box Packaging Robot

    CERN Document Server

    Yang, Heran; Cong, Matthew; Saxena, Ashutosh

    2011-01-01

    Given a point cloud, we consider inferring kinematic models of 3D articulated objects such as boxes for the purpose of manipulating them. While previous work has shown how to extract a planar kinematic model (often represented as a linear chain), such planar models do not apply to 3D objects that are composed of segments often linked to the other segments in cyclic configurations. We present an approach for building a model that captures the relation between the input point cloud features and the object segment as well as the relation between the neighboring object segments. We use a conditional random field that allows us to model the dependencies between different segments of the object. We test our approach on inferring the kinematic structure from partial and noisy point cloud data for a wide variety of boxes including cake boxes, pizza boxes, and cardboard cartons of several sizes. The inferred structure enables our robot to successfully close these boxes by manipulating the flaps.

  8. Forum for Change. An Articulation Workshop for Secondary and Post-Secondary Educators to Promote Equal Access in Vocational Education (Harlingen, Texas, February 17, 1984).

    Science.gov (United States)

    Education Service Center Region 2, Corpus Christi, TX.

    This volume contains materials for use in conducting an articulation workshop to train secondary and postsecondary educators to promote equal access to vocational education. Addressed in the individual sections of the guide are the following topics: inequalities in the workplace, the role of articulation in promoting equal access, outreach, career…

  9. Articulated Lifting System Modeling Based on Dynamics of Flexible Multi-Body Systems

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    In lifting sub-system of deep-sea mining system, spherical joint is used to connect lifting pipes to replace fixed joint. Based on Dynamics of Flexible Multi-body systems, the mechanics model of articulated lifting system is established. Under the four-grade and six-grade oceanic condition, dynamic responses of lifting system are simulated and experiment verified. The simulation results are consistent with experimental ones. The maximum moment of flexion is 322 kN-m on the first pipe under six-grade sea condition. It is seen that the articulated connection can reduce the moment of flexion. The bending deformation of pipe center is researched, and the maximum is 0.000479 m on the first pipe. Deformation has a little effect on the motion of system. It is feasible to analyze articulated lifting system by applying the theory of flexible multi-body dynamics. The articulated lifting system is obviously better than the fixed one.

  10. The Use of the Articulated Total Body Model as a Robot Dynamics Simulation Tool

    Science.gov (United States)

    1988-07-01

    AARL-SR-90-512 AD-A235 930l[liill ~i 11111111111 iIII J The Use of the Articulated Total Body Model as a Robot Dynamics Simulation Tool Louise A...R 4. TITLE AND SUBTITLE S. FUNDING NUMBERS The Use of the Articulated Total Body Model as a Robot Dynamics Simulation Tool PE 62202F 6. AUTHOR(S) PR...Lagrange method. In this paper the use of the ATH model as a robot dynamics simulation tool is discussed and various simulations are demonstrated. For this

  11. A K-12 Articulation Model for the Orange Unified School District.

    Science.gov (United States)

    Joseph, Louie S.

    This Maxi II practicum documents the development of a model articulation process and the implementation of that process in the Orange (California) Unified School District. The model was intended to improve the continuity of student progression through the grades from elementary to junior high to senior high school. Primary concerns of the…

  12. A Simulation Model Articulation of the REA Ontology

    Science.gov (United States)

    Laurier, Wim; Poels, Geert

    This paper demonstrates how the REA enterprise ontology can be used to construct simulation models for business processes, value chains and collaboration spaces in supply chains. These models support various high-level and operational management simulation applications, e.g. the analysis of enterprise sustainability and day-to-day planning. First, the basic constructs of the REA ontology and the ExSpect modelling language for simulation are introduced. Second, collaboration space, value chain and business process models and their conceptual dependencies are shown, using the ExSpect language. Third, an exhibit demonstrates the use of value chain models in predicting the financial performance of an enterprise.

  13. An Articulation Model in Dental Assisting for the Commonwealth of Pennsylvania. A Continuation.

    Science.gov (United States)

    Sylves, Jane M.; Boody, Sandra

    A curriculum development project was conducted to generate additional competency-based modules to be used within the articulation model for Pennsylvania dental assisting programs, established in 1988. Project activities included reviewing, modifying, and providing parallel competency-based structure for the courses at the A.W. Beattie Technical…

  14. [Occlusion, articulated and articulation].

    Science.gov (United States)

    De Boever, J A

    1990-01-01

    In this paper the so-called 'normal' or 'ideal' occlusal relationships are described in static centric as well as in dynamic, eccentric positions. However, difference is made between the different occlusal concepts. There is no real antagonism between the 'physiologic occlusal concept' in natural dentition and the 'therapeutic occlusal concept' on which the treatment should be based in restoring the occlusion. The different forms of occlusion and articulation found in the natural dentition are the expression of physiologic, biological variations. The rest position of the mandible is an unreliable reference point in occlusal rehabilitation. Moderate attrition in older patients should not be considered as pathologic and there is no indication for treatment in absence of functional pathology.

  15. Modeling, Simulation and Position Control of 3 Degree of Freedom Articulated Manipulator

    Directory of Open Access Journals (Sweden)

    Hossein Sadegh Lafmejani

    2013-09-01

    Full Text Available In this paper, the modeling, simulation and control of 3 degree of freedom articulated robotic manipulator have been studied. First, we extracted kinematics and dynamics equations of the mentioned manipulator by using the Lagrange method. In order to validate the analytical model of the manipulator we compared the model simulated in the simulation environment of Matlab with the model was simulated with the SimMechanics toolbox. A sample path has been designed for analyzing the tracking subject. The system has been linearized with feedback linearization and then a PID controller was applied to track a reference trajectory. Finally, the control results have been compared with a nonlinear PID controller.

  16. Fuzzy Control of Yaw and Roll Angles of a Simulated Helicopter Model Includes Articulated Manipulators

    Directory of Open Access Journals (Sweden)

    Hossein Sadegh Lafmejani

    2015-09-01

    Full Text Available Fuzzy logic controller (FLC is a heuristic method by If-Then Rules which resembles human intelligence and it is a good method for designing Non-linear control systems. In this paper, an arbitrary helicopter model includes articulated manipulators has been simulated with Matlab SimMechanics toolbox. Due to the difficulties of modeling this complex system, a fuzzy controller with simple fuzzy rules has been designed for its yaw and roll angles in order to stabilize the helicopter while it is in the presence of disturbances or its manipulators are moving for a task. Results reveal that a simple FLC can appropriately control this system.

  17. A New Flatness Pattern Recognition Model Based on Cerebellar Model Articulation Controllers Network

    Institute of Scientific and Technical Information of China (English)

    HE Hai-tao; LI Yan

    2008-01-01

    In the traditional flatness pattern recognition neural network,the topologic configurations need to be rebuilt with a changing width of cold strip.Furthermore,the large learning assignment,slow convergence,and local minimum in the network are observed.Moreover,going by the structure of the tradtional neural network,according to experience,the model is time-consuming and complex.Thus,a new approach of flatness pattern recognition is proposed based on the CMAC (cerebellar model articulation controllers) neural network.The difference in fuzzy distances between samples and the basic patterns is introduced as the input of the CMAC network.Simultaneously,the adequate learning rate is improved in the error correction algorithm of this neural network.The new approach with advantages,such as high learning speed,good generalization,and easy implementation,is efficient and intelligent.The simulation results show that the speed and accuracy of the flatness pattern recognition model are obviously improved.

  18. The use of the articulated total body model as a robot dynamics simulation tool

    Science.gov (United States)

    Obergfell, Louise A.; Avula, Xavier J. R.; Kalegs, Ints

    1988-01-01

    The Articulated Total Body (ATB) model is a computer sumulation program which was originally developed for the study of aircrew member dynamics during ejection from high-speed aircraft. This model is totally three-dimensional and is based on the rigid body dynamics of coupled systems which use Euler's equations of motion with constraint relations of the type employed in the Lagrange method. In this paper the use of the ATB model as a robot dynamics simulation tool is discussed and various simulations are demonstrated. For this purpose the ATB model has been modified to allow for the application of torques at the joints as functions of state variables of the system. Specifically, the motion of a robotic arm with six revolute articulations with joint torques prescribed as functions of angular displacement and angular velocity are demonstrated. The simulation procedures developed in this work may serve as valuable tools for analyzing robotic mechanisms, dynamic effects, joint load transmissions, feed-back control algorithms employed in the actuator control and end-effector trajectories.

  19. Articulating Atmospheres

    DEFF Research Database (Denmark)

    Kinch, Sofie

    2011-01-01

    This paper presents an architectural approach to designing computational interfaces by articulating the notion of atmosphere in the field of interaction design. It draws upon the concept of kinesthetic interaction and a philosophical notion on atmosphere emphasizing the importance of bodily...... experience in space, presented as middle ground experience. In the field of HCI, middle ground experiences complete the unarticulated spectrum between designing for foreground of attention or background awareness. When “Articulating Atmospheres through Middle Ground Experiences in Interaction Design...

  20. A Parametric Model of Shoulder Articulation for Virtual Assessment of Space Suit Fit

    Science.gov (United States)

    Kim, K. Han; Young, Karen S.; Bernal, Yaritza; Boppana, Abhishektha; Vu, Linh Q.; Benson, Elizabeth A.; Jarvis, Sarah; Rajulu, Sudhakar L.

    2016-01-01

    Shoulder injury is one of the most severe risks that have the potential to impair crewmembers' performance and health in long duration space flight. Overall, 64% of crewmembers experience shoulder pain after extra-vehicular training in a space suit, and 14% of symptomatic crewmembers require surgical repair (Williams & Johnson, 2003). Suboptimal suit fit, in particular at the shoulder region, has been identified as one of the predominant risk factors. However, traditional suit fit assessments and laser scans represent only a single person's data, and thus may not be generalized across wide variations of body shapes and poses. The aim of this work is to develop a software tool based on a statistical analysis of a large dataset of crewmember body shapes. This tool can accurately predict the skin deformation and shape variations for any body size and shoulder pose for a target population, from which the geometry can be exported and evaluated against suit models in commercial CAD software. A preliminary software tool was developed by statistically analyzing 150 body shapes matched with body dimension ranges specified in the Human-Systems Integration Requirements of NASA ("baseline model"). Further, the baseline model was incorporated with shoulder joint articulation ("articulation model"), using additional subjects scanned in a variety of shoulder poses across a pre-specified range of motion. Scan data was cleaned and aligned using body landmarks. The skin deformation patterns were dimensionally reduced and the co-variation with shoulder angles was analyzed. A software tool is currently in development and will be presented in the final proceeding. This tool would allow suit engineers to parametrically generate body shapes in strategically targeted anthropometry dimensions and shoulder poses. This would also enable virtual fit assessments, with which the contact volume and clearance between the suit and body surface can be predictively quantified at reduced time and

  1. Real-time integrated process supervision for autotuners and modified cerebellar model articulation controller

    Science.gov (United States)

    Wahab, Abdul; Quek, H. C.; Lim, B. H.

    1998-10-01

    This paper presents the use of a micro-controller-based Integrated Process Supervision as a tool for investigate work in expert control. Two different control theories integrated within process serve as examples of structured approach to expert control. The Integrated Process Supervision is a refinement of the Expert Control Architecture as proposed by Karl J. Astrom by allowing integration of several control techniques in a single generic framework. Specifically, the paper presents the result for experiments performed on an implementation of the Integrated Process Supervision on a PC and micro-controller environment. Autotuning techniques were first integrated within the process supervision. Three Autotuners based on specification of phase and amplitude margins were investigated. A modified version of Cerebellar MOdel Articulation Controller was then implemented in IPS as a direct controller. Results collected verify its integration in the integrated process supervision and also provide evidence of improved performance as compared to Autotuning.

  2. Advancing Health Promotion in Dentistry: Articulating an Integrative Approach to Coaching Oral Health Behavior Change in the Dental Setting.

    Science.gov (United States)

    Vernon, Lance T; Howard, Anita R

    2015-09-01

    Oral health is managed based on objective measures such as the presence and severity of dental caries and periodontal disease. In recent years, oral health researchers and practitioners have shown increasing interest in a widened array of physical, psychological, and social factors found to influence patients' oral health. In this article, we introduce a behavior change coaching approach that can be used to enhance psychosocial diagnosis and client-centered delivery of health-promoting interventions. Briefly, this health coaching approach is based on an interactive assessment (both physical and psychological), a non-judgmental exploration of patients' knowledge, attitudes, and beliefs, a mapping of patient behaviors that may contribute to disease progression, gauging patient motivation, and tailoring health communication to encourage health-promoting behavior change. Developed in a clinical setting, this coaching model is supported by interdisciplinary theory, research, and practice on health behavior change. We suggest that, with supervision, this coaching process may be learned.

  3. Adaptive Filter Design Using Type-2 Fuzzy Cerebellar Model Articulation Controller.

    Science.gov (United States)

    Lin, Chih-Min; Yang, Ming-Shu; Chao, Fei; Hu, Xiao-Min; Zhang, Jun

    2016-10-01

    This paper aims to propose an efficient network and applies it as an adaptive filter for the signal processing problems. An adaptive filter is proposed using a novel interval type-2 fuzzy cerebellar model articulation controller (T2FCMAC). The T2FCMAC realizes an interval type-2 fuzzy logic system based on the structure of the CMAC. Due to the better ability of handling uncertainties, type-2 fuzzy sets can solve some complicated problems with outstanding effectiveness than type-1 fuzzy sets. In addition, the Lyapunov function is utilized to derive the conditions of the adaptive learning rates, so that the convergence of the filtering error can be guaranteed. In order to demonstrate the performance of the proposed adaptive T2FCMAC filter, it is tested in signal processing applications, including a nonlinear channel equalization system, a time-varying channel equalization system, and an adaptive noise cancellation system. The advantages of the proposed filter over the other adaptive filters are verified through simulations.

  4. Articulating uncertainty as part of scientific argumentation during model-based exoplanet detection tasks

    Science.gov (United States)

    Lee, Hee-Sun; Pallant, Amy; Pryputniewicz, Sarah

    2015-08-01

    Teaching scientific argumentation has emerged as an important goal for K-12 science education. In scientific argumentation, students are actively involved in coordinating evidence with theory based on their understanding of the scientific content and thinking critically about the strengths and weaknesses of the cited evidence in the context of the investigation. We developed a one-week-long online curriculum module called "Is there life in space?" where students conduct a series of four model-based tasks to learn how scientists detect extrasolar planets through the “wobble” and transit methods. The simulation model allows students to manipulate various parameters of an imaginary star and planet system such as planet size, orbit size, planet-orbiting-plane angle, and sensitivity of telescope equipment, and to adjust the display settings for graphs illustrating the relative velocity and light intensity of the star. Students can use model-based evidence to formulate an argument on whether particular signals in the graphs guarantee the presence of a planet. Students' argumentation is facilitated by the four-part prompts consisting of multiple-choice claim, open-ended explanation, Likert-scale uncertainty rating, and open-ended uncertainty rationale. We analyzed 1,013 scientific arguments formulated by 302 high school student groups taught by 7 teachers. We coded these arguments in terms of the accuracy of their claim, the sophistication of explanation connecting evidence to the established knowledge base, the uncertainty rating, and the scientific validity of uncertainty. We found that (1) only 18% of the students' uncertainty rationale involved critical reflection on limitations inherent in data and concepts, (2) 35% of students' uncertainty rationale reflected their assessment of personal ability and knowledge, rather than scientific sources of uncertainty related to the evidence, and (3) the nature of task such as the use of noisy data or the framing of

  5. The psychoacoustics of musical articulation

    Science.gov (United States)

    Spiegelberg, Scott Charles

    This dissertation develops psychoacoustical definitions of notated articulations, the necessary first step in articulation research. This research can be useful to theorists interested in timbre analysis, the psychology of performance, analysis and performance, the psychology of style differentiation, and performance pedagogy. An explanation of wavelet transforms precedes the development of new techniques for analyzing transient sounds. A history of timbre perception research reveals the inadequacies of current sound segmentation models, resulting in the creation of a new model, the Pitch/Amplitude/Centroid Trajectory (PACT) model of sound segmentation. The new analysis techniques and PACT model are used to analyze recordings of performers playing a melodic fragment in a series of notated articulations. Statistical tests showed that the performers generally agreed on the interpretation of five different articulation groups. A cognitive test of articulation similarity, using musicians and non-musicians as participants, revealed a close correlation between similarity judgments and physical attributes, though additional unknown factors are clearly present. A second psychological test explored the perceptual salience of articulation notation, by asking musically-trained participants to match stimuli to the same notations the performers used. The participants also marked verbal descriptors for each articulation, such as short/long, sharp/dull, loud/soft, harsh/gentle, and normal/extreme. These results were matched against the results of Chapters Five and Six, providing an overall interpretation of the psychoacoustics of articulation.

  6. Articulated Total Body Model Enhancements. Volume 3. Programmer’s Guide

    Science.gov (United States)

    1988-02-01

    BY U INDEX OF NTAB ARRAY. FRCDFL C DERIVATIVE, FUNCTION OR INTEGRAL IS EVALUATED AS N =0,1 OR 2. FRCDFL C ETAB (N) - INDEX TO TAB ARRAY FOR REAL DATA...6. Leetch, B.D., Bowman, W.L., "Articulated Total Body (AmB) VIEW Program Software Report," Report Nos. AMRL-TR-81-111, Vols 1 & 2, June * 1983 (NTIS

  7. The virtual articulator.

    Science.gov (United States)

    Bisler, A; Bockholt, U; Kordass, B; Suchan, M; Voss, G

    2002-01-01

    The virtual articulator (VA) is intended for use as a tool for the analysis fo the complex static and dynamic occlusal relations. Its chief application is in individual diagnosis and the simulation of the mechanical articulator. As entry data, the VA requires digital, 3-dimensional representations of the jaws and patient-specific data on jaw movement. It then simulates jaw movement and provides a dynamic visualization of the occlusal contacts. If no patient-specific data are available, the modus operandi of the mechanical articulator can be simulated. Virtual reality (VR) techniques applied in computer-aided diagnosis are revolutionizing medical routine in many disciplines. Particularly in the field of dental engineering, VR combined with CAD/CAM technology has great potential in implant planning and design in terms of greater precision and shorter treatment duration. The geometry of teeth can be digitized, the implant models can be designed with specialized CAD systems, and the final implants can be manufactured with a CNC machine. In this context, the virtual articulator completes the digital manufacturing process.

  8. Recognizing articulated objects and object articulation in SAR images

    Science.gov (United States)

    Bhanu, Bir; Jones, Grinnell, III; Ahn, Joon S.

    1998-09-01

    The focus of this paper is recognizing articulated objects and the pose of the articulated parts in SAR images. Using SAR scattering center locations as features, the invariance with articulation (i.e. turret rotation for the T72, T80 and M1a tanks, missile erect vs. down for the SCUD launcher) is shown as a function of object azimuth. Similar data is shown for configuration differences in the MSTAR (Public) Targets. The UCR model-based recognition engine (which uses non- articulated models to recognize articulated, occluded and non-standard configuration objects) is described and target identification performance results are given as confusion matrices and ROC curves for six inch and one foot resolution XPATCH images and the one foot resolution MSTAR data. Separate body and turret models are developed that are independent of the relative positions between the body and the turret. These models are used with a subsequent matching technique to refine the pose of the body and determine the pose of the turret. An expression of the probability that a random match will occur is derived and this function is used to set thresholds to minimize the probability of a random match for the recognition system. Results for identification, body pose and turret pose are presented as a function of percent occlusion for articulated XPATCH data and results are given for identification and body pose for articulated MSTAR data.

  9. Student articulation of a nursing philosophical statement: an assignment to enhance critical thinking skills and promote learning.

    Science.gov (United States)

    Hernandez, Cheri Ann

    2009-06-01

    The development of a personal philosophical statement about nursing is a useful assignment for both undergraduate and graduate nursing students. Students are asked to write a paper describing their philosophical views about nursing related to the metaparadigm concepts and include in-depth examples from their clinical practice to illustrate these views. This article includes information regarding important preparatory activities and handouts to facilitate the writing and evaluation of this assignment. There are many potential benefits of this complex assignment. It promotes students' reflection on their personal clinical practice experiences and engages students in mental and verbal dialogue that elicits their philosophical ideas about the metaparadigm concepts. These activities promote critical thinking and reflective clinical practice, act as a foundation for building theoretical understanding, and promote confidence in learning about nursing and other theories.

  10. Malay Wordlist Modeling for Articulation Disorder Patient by Using Computerized Speech Diagnosis System

    Directory of Open Access Journals (Sweden)

    Mohd Nizam Mazenan

    2014-05-01

    Full Text Available The aim of this research was to assess the quality and the impact of using computerized speech diagnosis system to overcome the problem of speech articulation disorder among Malaysian context. The prototype of the system is already been develop in order to help Speech Therapist (ST or Speech Language Pathologist (SLP in diagnosis, preventing and treatment for an early stage. Few assessments will be conducted by ST over the patient and mostly the process is still using manual technique whereby the ST relies from their human hearing and their years of experience. This study will surveys the technique and method use by ST at Hospital Sultanah Aminah (HSA (Speech therapist at Speech Therapy Center to help patient that suffer from speech disorder especially in articulation disorder cases. Few experiment and result had also been present in this study where the computerized speech diagnosis system is being tested by using real patient voice sample that been collected from HSA and the students from Sekolah Kebangsaan Taman Universiti Satu.

  11. Modelling and Calibration Technique of Laser Triangulation Sensors for Integration in Robot Arms and Articulated Arm Coordinate Measuring Machines

    Directory of Open Access Journals (Sweden)

    Juan J. Aguilar

    2009-09-01

    Full Text Available A technique for intrinsic and extrinsic calibration of a laser triangulation sensor (LTS integrated in an articulated arm coordinate measuring machine (AACMM is presented in this paper. After applying a novel approach to the AACMM kinematic parameter identification problem, by means of a single calibration gauge object, a one-step calibration method to obtain both intrinsic―laser plane, CCD sensor and camera geometry―and extrinsic parameters related to the AACMM main frame has been developed. This allows the integration of LTS and AACMM mathematical models without the need of additional optimization methods after the prior sensor calibration, usually done in a coordinate measuring machine (CMM before the assembly of the sensor in the arm. The experimental tests results for accuracy and repeatability show the suitable performance of this technique, resulting in a reliable, quick and friendly calibration method for the AACMM final user. The presented method is also valid for sensor integration in robot arms and CMMs.

  12. Modelling and calibration technique of laser triangulation sensors for integration in robot arms and articulated arm coordinate measuring machines.

    Science.gov (United States)

    Santolaria, Jorge; Guillomía, David; Cajal, Carlos; Albajez, José A; Aguilar, Juan J

    2009-01-01

    A technique for intrinsic and extrinsic calibration of a laser triangulation sensor (LTS) integrated in an articulated arm coordinate measuring machine (AACMM) is presented in this paper. After applying a novel approach to the AACMM kinematic parameter identification problem, by means of a single calibration gauge object, a one-step calibration method to obtain both intrinsic-laser plane, CCD sensor and camera geometry-and extrinsic parameters related to the AACMM main frame has been developed. This allows the integration of LTS and AACMM mathematical models without the need of additional optimization methods after the prior sensor calibration, usually done in a coordinate measuring machine (CMM) before the assembly of the sensor in the arm. The experimental tests results for accuracy and repeatability show the suitable performance of this technique, resulting in a reliable, quick and friendly calibration method for the AACMM final user. The presented method is also valid for sensor integration in robot arms and CMMs.

  13. Studying the Accuracy of Software Process Elicitation: The User Articulated Model

    Science.gov (United States)

    Crabtree, Carlton A.

    2010-01-01

    Process models are often the basis for demonstrating improvement and compliance in software engineering organizations. A descriptive model is a type of process model describing the human activities in software development that actually occur. The purpose of a descriptive model is to provide a documented baseline for further process improvement…

  14. A component modes projection and assembly model reduction methodology for articulated, multi-flexible body structures

    Science.gov (United States)

    Lee, Allan Y.; Tsuha, Walter S.

    1993-01-01

    A two-stage model reduction methodology, combining the classical Component Mode Synthesis (CMS) method and the newly developed Enhanced Projection and Assembly (EP&A) method, is proposed in this research. The first stage of this methodology, called the COmponent Modes Projection and Assembly model REduction (COMPARE) method, involves the generation of CMS mode sets, such as the MacNeal-Rubin mode sets. These mode sets are then used to reduce the order of each component model in the Rayleigh-Ritz sense. The resultant component models are then combined to generate reduced-order system models at various system configurations. A composite mode set which retains important system modes at all system configurations is then selected from these reduced-order system models. In the second stage, the EP&A model reduction method is employed to reduce further the order of the system model generated in the first stage. The effectiveness of the COMPARE methodology has been successfully demonstrated on a high-order, finite-element model of the cruise-configured Galileo spacecraft.

  15. Variable structure multiple model for articulated human motion tracking from monocular video sequences

    Institute of Scientific and Technical Information of China (English)

    HAN Hong; TONG MingLei; CHEN ZhiChao; FAN YouJian

    2012-01-01

    A new model-based human body tracking framework with learning-based theory is introduced inthis paper.We propose a variable structure multiple model (VSMM) framework to address challenging problems such as uncertainty of motion styles,imprecise detection of feature points,and ambiguity of joint locations.Key human joint points are detected automatically and the undetected points are estimated with Kalman filters.Multiple motion models are learned from motion capture data using a ridge regression method.The model set that covers the total motion set is designed on the basis of topological and compatibility relationships,while the VSMM algorithm is used to estimate quaternion vectors of joint rotation.Experiments using real image sequences and simulation videos demonstrate the high efficiency of our proposed human tracking framework.

  16. Learning by Modeling (LbM: Understanding Complex Systems by Articulating Structures, Behaviors, and Functions

    Directory of Open Access Journals (Sweden)

    Kamel Hashem

    2013-05-01

    Full Text Available Understanding the behavior of complex systems has become a focal issue for scientists in a wide range of disciplines. Making sense of a complex system should require that a student construct a network of concepts and principles about the learning complex phenomena. This paper describes part of a project about Learning-by-Modeling (LbM. Many features of complex systems make it difficult for students to develop deep understanding. Previous research indicates that involvement with modeling scientific phenomena and complex systems can play a powerful role in science learning. Some researchers argue with this view indicating that models and modeling do not contribute to understanding complexity concepts, since these increases the cognitive load on students. In this study we investigated the effect of different modes of involvement in exploring scientific phenomena using computer simulation tools, on students’ mental model from the perspective of structure, behaviour and function. Quantitative and qualitative methods are used to report about 121 freshmen students that engaged in participatory simulations about complex phenomena, showing emergent, self-organized and decentralized patterns. Results show that LbM plays a major role in students' concept formation about complexity concepts.

  17. Virtual articulators in prosthodontics

    National Research Council Canada - National Science Library

    R.S., Gugwad; M., Basavakumar; K., Abhijeet; M., Arvind; M., Sudhindra; C., Ramesh

    2011-01-01

    Virtual technologies in dentistry provide better education and training by simulating complex contexts and enhancing procedures that are traditionally limited, such as work with mechanical articulator...

  18. Understanding Complex Natural Systems by Articulating Structure-Behavior-Function Models

    Science.gov (United States)

    Vattam, Swaroop S.; Goel, Ashok K.; Rugaber, Spencer; Hmelo-Silver, Cindy E.; Jordan, Rebecca; Gray, Steven; Sinha, Suparna

    2011-01-01

    Artificial intelligence research on creative design has led to Structure-Behavior-Function (SBF) models that emphasize functions as abstractions for organizing understanding of physical systems. Empirical studies on understanding complex systems suggest that novice understanding is shallow, typically focusing on their visible structures and…

  19. An Adaptive Supervisory Sliding Fuzzy Cerebellar Model Articulation Controller for Sensorless Vector-Controlled Induction Motor Drive Systems

    Directory of Open Access Journals (Sweden)

    Shun-Yuan Wang

    2015-03-01

    Full Text Available This paper presents the implementation of an adaptive supervisory sliding fuzzy cerebellar model articulation controller (FCMAC in the speed sensorless vector control of an induction motor (IM drive system. The proposed adaptive supervisory sliding FCMAC comprised a supervisory controller, integral sliding surface, and an adaptive FCMAC. The integral sliding surface was employed to eliminate steady-state errors and enhance the responsiveness of the system. The adaptive FCMAC incorporated an FCMAC with a compensating controller to perform a desired control action. The proposed controller was derived using the Lyapunov approach, which guarantees learning-error convergence. The implementation of three intelligent control schemes—the adaptive supervisory sliding FCMAC, adaptive sliding FCMAC, and adaptive sliding CMAC—were experimentally investigated under various conditions in a realistic sensorless vector-controlled IM drive system. The root mean square error (RMSE was used as a performance index to evaluate the experimental results of each control scheme. The analysis results indicated that the proposed adaptive supervisory sliding FCMAC substantially improved the system performance compared with the other control schemes.

  20. The extraordinary joint material of an articulated coralline alga. II. Modeling the structural basis of its mechanical properties.

    Science.gov (United States)

    Denny, Mark W; King, Felicia A

    2016-06-15

    By incorporating joints into their otherwise rigid fronds, erect coralline algae have evolved to be as flexible as other seaweeds, which allows them to thrive - and even dominate space - on wave-washed shores around the globe. However, to provide the required flexibility, the joint tissue of Calliarthron cheilosporioides, a representative articulated coralline alga, relies on an extraordinary tissue that is stronger, more extensible and more fatigue resistant than that of other algae. Here, we used the results from recent experiments to parameterize a conceptual model that links the microscale architecture of cell walls to the adaptive mechanical properties of joint tissue. Our analysis suggests that the theory of discontinuous fiber-wound composite materials (with cellulose fibrils as the fibers and galactan gel as the matrix) can explain key aspects of the material's mechanics. In particular, its adaptive viscoelastic behavior can be characterized by two, widely separated time constants. We speculate that the short time constant (∼14 s) results from the viscous response of the matrix to the change in cell-wall shape as a joint is stretched, a response that allows the material both to remain flexible and to dissipate energy as a frond is lashed by waves. We propose that the long time constant (∼35 h), is governed by the shearing of the matrix between cellulose fibrils. The resulting high apparent viscosity ensures that joints avoid accumulating lethal deformation in the course of a frond's lifetime. Our synthesis of experimental measurements allows us to draw a chain of mechanistic inference from molecules to cell walls to fronds and community ecology.

  1. Positive Role Models vs. Bullies: Can They Be Distinguished by Following Articulate Animals into Worlds of Suspended Disbelief?

    Science.gov (United States)

    Miller, Suzanne

    2011-01-01

    Orally and later in written form, stories have been used to identify and reinforce the values of a culture. The parables of the Bible and the vocalization of articulate animals in Aesop fables continue to be used to teach morals to children. While the majority of existing research investigates the effective use of animals as a tool in character…

  2. Pender's health promotion model in medical research.

    Science.gov (United States)

    Heydari, Abbas; Khorashadizadeh, Fatemeh

    2014-09-01

    This review shows how researchers use pander's health promotion model. We included all articles in which Pender's health promotion has been used for theoretical framework. Eligible articles were selected according to review of abstracts. Search was conducted using the electronic database from 1990 to 2012. Based on our search, 74 articles with various methodologies were relevant for review. Their aims of these studies were to predict effective factors/barriers in health promotion behaviours, to detect effects of intervention programme for improving health promotion behaviours, test the model, identify quality of life and health promotion behaviour, predict stage of change in related factors that affect health promotion behaviour, prevent the events that interfere with health promotion behaviour, develop another model similar to this model, compare this model with another model, determine the relationship of variables associated to health promotion behaviours.

  3. Modelling and Calibration Technique of Laser Triangulation Sensors for Integration in Robot Arms and Articulated Arm Coordinate Measuring Machines

    OpenAIRE

    Aguilar, Juan J.; Albajez, José A.; Carlos Cajal; David Guillomía; Jorge Santolaria

    2009-01-01

    A technique for intrinsic and extrinsic calibration of a laser triangulation sensor (LTS) integrated in an articulated arm coordinate measuring machine (AACMM) is presented in this paper. After applying a novel approach to the AACMM kinematic parameter identification problem, by means of a single calibration gauge object, a one-step calibration method to obtain both intrinsic―laser plane, CCD sensor and camera geometry―and extrinsic parameters related to the AACMM main frame has been develope...

  4. Lingual articulation in songbirds.

    Science.gov (United States)

    Suthers, Roderick A; Rothgerber, John R; Jensen, Kenneth Kragh

    2016-02-01

    Lingual articulation in humans is one of the primary means of vocal tract resonance filtering that produces the characteristic vowel formants of speech. In songbirds, the function of the tongue in song has not been thoroughly examined, although recent research has identified the oropharyngeal-esophageal cavity as a resonance filter that is actively tuned to the frequency of the song. In northern cardinals (Cardinalis cardinalis), the volume of this cavity is inversely proportional to the frequency of the song above 2 kHz. However, cardinal song extends below this range, leaving the question of whether and how the vocal tract is tracking these low frequencies. We investigated the possible role of the tongue in vocal tract filtering using X-ray cineradiography of northern cardinals. Below 2 kHz, there was prominent tongue elevation in which the tip of the tongue was raised until it seemed to touch the palate. These results suggest that tongue elevation lowers the resonance frequency below 2 kHz by reducing the area of the passage from the oral cavity into the beak. This is consistent with a computational model of the songbird vocal tract in which resonance frequencies are actively adjusted by both changing the volume of the oropharyngeal-esophageal cavity and constricting the opening into the beak.

  5. Extensional Information Articulation from the Universe

    OpenAIRE

    Yasufumi Saruwatari; Makoto Yoshitake

    2012-01-01

    Information must have physical support and this physical universe comprisesphysical interactions. Hence actual information processes should have a description byinteractions alone, i.e., an extensional description. In this paper, such a model of the processof information articulation from the universe is developed by generalizing the extensivemeasurement theory in metrology. Moreover, a model of the attribute creation processis presented to exemplify a step of the informational articulation p...

  6. Lunar articulated remote transportation system

    Science.gov (United States)

    1990-01-01

    The students of the Florida A&M/Florida State University College of Engineering continued their design from 1988 to 1989 on a first generation lunar transportation vehicle for use on the surface of the Moon between the years 2010 and 2020. Attention is focused on specific design details on all components of the Lunar Articulated Remote Transportation System (Lunar ARTS). The Lunar ARTS will be a three-cart, six-wheeled articulated vehicle. Its purpose will be the transportation of astronauts and/or materials for excavation purposes at a short distance from the base (37.5 km). The power system includes fuel cells for both the primary system and the back-up system. The vehicle has the option of being operated in a manned or unmanned mode. The unmanned mode includes stereo imaging with signal processing for navigation. For manned missions the display console is a digital readout displayed on the inside of the astronaut's helmet. A microprocessor is also on board the vehicle. Other components of the vehicle include a double wishbone/flexible hemispherical wheel suspension; chassis; a steering system; motors; seat retraints; heat rejection systems; solar flare protection; dust protection; and meteoroid protection. A one-quarter scale dynamic model has been built to study the dynamic behavior of the vehicle. The dynamic model closely captures the mechanical and electrical details of the total design.

  7. Face bow and articulator for planning orthognathic surgery: 2 articulator.

    Science.gov (United States)

    Walker, Fraser; Ayoub, Ashraf F; Moos, Khursheed F; Barbenel, Joseph

    2008-10-01

    Patients who require orthognathic surgery may have asymmetry of the position of the temporomandibular joints relative to the maxilla, which is impossible to reproduce on the current semiadjustable articulators used for surgical planning. We describe a highly-adjustable spirit level orthognathic face bow that allows records to be made of patients with asymmetrical maxillae. The orthognathic articulator also allows the position of the condylar components of the articulator to be adjusted in three dimensions. The use of the new face bow and articulator made it possible to mount the dental casts of asymmetrical faces to reproduce their clinical appearance. The devices were evaluated by comparing the measurements of anatomical variables obtained from cephalometric radiographs with equivalent values obtained from the orthognathic articulator and casts mounted on the articulator. Although the measurements showed significant intersubject variability, the angle between the horizontal and maxillary occlusal plane, occlusal cant angle, and intercondylar widths, were not significantly different.

  8. Bayesian distributed articulated object tracking using multiple collaborative trackers

    Science.gov (United States)

    Qu, Wei; Schonfeld, Dan

    2007-01-01

    In this paper, we propose two novel articulated object tracking approaches. The Decentralized Articulated Object Tracking approach avoids the common practice of using a high-dimensional joint state representation for articulated object tracking. Instead, it introduces a decentralized scheme and models the inter-part interaction within an innovative Bayesian framework. To handle severe self-occlusions, we further extend the first approach by modeling high-level inter-unit interactions and develop the Hierarchical Articulated Object Tracking algorithm within a consistent hierarchical framework. Preliminary experimental results have demonstrated the superior performance of the proposed approaches for real-world videos sequences.

  9. Extensional Information Articulation from the Universe

    Directory of Open Access Journals (Sweden)

    Yasufumi Saruwatari

    2012-11-01

    Full Text Available Information must have physical support and this physical universe comprisesphysical interactions. Hence actual information processes should have a description byinteractions alone, i.e., an extensional description. In this paper, such a model of the processof information articulation from the universe is developed by generalizing the extensivemeasurement theory in metrology. Moreover, a model of the attribute creation processis presented to exemplify a step of the informational articulation process. These modelsdemonstrate the valuableness of the extensional view and are expected to enhance theunderstanding of the extensional aspects of fundamentals of information.

  10. Predicting articulated human motion from spatial processes

    DEFF Research Database (Denmark)

    Hauberg, Søren; Pedersen, Kim Steenstrup

    2011-01-01

    We present a probabilistic interpretation of inverse kinematics and extend it to sequential data. The resulting model is used to estimate articulated human motion in visual data. The approach allows us to express the prior temporal models in spatial limb coordinates, which is in contrast to most...

  11. Articulator selection for restorative dentistry.

    Science.gov (United States)

    Hobo, S; Shillingburg, H T; Whitsett, L D

    1976-07-01

    There are many types of articulators that can be used for making fixed restorations. While unquestionably the most accurate, the fully adjustable instrument is not feasible or necessary for many forms of simple occlusal treatment. The effects of tooth-hinge axis radius, intercondylar distance, and condylar inclination on occlusal morphology have been discussed. Guidelines have been proposed for matching the type of articulator with the extent of treatment anticipated. The use of small, nonadjustable hinge articulators is not recommended.

  12. Articulating Material Criteria

    DEFF Research Database (Denmark)

    Hasling, Karen Marie

    2013-01-01

    This paper discusses the experiences and potentials with materials teaching at the Institute for Product Design at Kolding School of Design, using materials teaching as experiments in my PhD project. The project intents to create a stronger material awareness among product design students...... with emphasis on sustainability. The experiments aim to develop an understanding of, how product design students include materials in their design practice and how tools can be developed that further enhance this. Hence experiments are essential for the progress of the PhD project as they help to observe......, imitate and articulate the students’ inclusion of materials. This paper particularly discusses the experiences made and ideas generated after the execution of a material science course for second year students, with emphasis on the concept of the material selection matrix as an educational tool...

  13. Intelligent Articulated Robot

    Science.gov (United States)

    Nyein, Aung Kyaw; Thu, Theint Theint

    2008-10-01

    In this paper, an articulated type of industrial used robot is discussed. The robot is mainly intended to be used in pick and place operation. It will sense the object at the specified place and move it to a desired location. A peripheral interface controller (PIC16F84A) is used as the main controller of the robot. Infrared LED and IR receiver unit for object detection and 4-bit bidirectional universal shift registers (74LS194) and high current and high voltage Darlington transistors arrays (ULN2003) for driving the arms' motors are used in this robot. The amount of rotation for each arm is regulated by the limit switches. The operation of the robot is very simple but it has the ability of to overcome resetting position after power failure. It can continue its work from the last position before the power is failed without needing to come back to home position.

  14. Cognitive predictors of articulation in writing.

    Science.gov (United States)

    Wormack, L

    1979-06-01

    Among 106 college students scores on a spontaneous 20-min. essay were regressed on referents of verbal and visual spatial ability. 26% of the variability in writing articulation among males was accounted for by the regression of graded writing scores against logical relations and embedded figures tests. 82% of the variability in writing ability among (females was accounted for by the regression of graded writing scores on visual closure, reading comprehension, spatial visualization, and embedded figures tests. The use of verbal and visual sptial referents as predictors of the degree of articulation in spontaneous writing samples consistent with sex-specific models of.cerebral lateralization was described.

  15. Psychosocial environment: a health promotion model.

    Science.gov (United States)

    Kar, S B

    1983-01-01

    This article presents a multidimensional model of psychosocial determinants of health behavior for health promotion research and policy analysis. Frequently, health promotion focuses almost exclusively on intrapsychic determinants and on individual level behavior. Based upon Field Theory and attitude theories, this proposed model holds that in populations with comparable sociodemographic and biological status (exogenous variables) a health behavior is a function of direct and interaction effects of five key intrapsychic and external variables. These are: behavioral intentions, social support, accessibility of means for action, personal autonomy, and action situation. Empirical tests with cross-cultural studies in Venezuela, Kenya, and the Philippines provide substantial support for the model. The findings suggest that while health promotion strategies should deal with intrapsychic determinants of behavior, key extrapsychic factors (such as social support, quality and accessibility of health care measures, and situational factors) all have direct and independent effects on health behavior as well. Health promotion research and interventions which aim exclusively at intrapsychic determinants would thus have rather limited overall value. The article discusses key research and policy implications of the model presented.

  16. Application of Cerebellar Model Articulation Controller(CMAC) with a Modified Algorithm in Monitoring Machine Performance Degradation

    Institute of Scientific and Technical Information of China (English)

    ZHANG Jing-yong; ZHANG Lei; CAO Qi-xin; Jay Lee

    2005-01-01

    On the basis of CMAC-PDM (Pattern Discrimination Model), a novel algorithm of CMAC for monitoring machine degradation is proposed in this paper. The output of CMAC with the novel algorithm represents the state of a machine and PDM is not needed. The principle was explained by analyzing the modified mapping process of CMAC. The novel CMAC is applied to a tool condition monitoring system and two methodologies (novel CMAC and CMAC-PDM) are compared. The results prove that the novel algorithm is feasible and its computational complexity is reduced significantly.

  17. Articulation Points in Complex Networks

    CERN Document Server

    Tian, Liang; Shi, Da-Ning; Liu, Yang-Yu

    2016-01-01

    An articulation point in a network is a node whose removal disconnects the network. Those nodes play key roles in ensuring connectivity of many real-world networks, from infrastructure networks to protein interaction networks and terrorist communication networks. Despite their fundamental importance, a general framework of studying articulation points in complex networks is lacking. Here we develop analytical tools to study key issues pertinent to articulation points, e.g. the expected number of them and the network vulnerability against their removal, in an arbitrary complex network. We find that a greedy articulation point removal process provides us a novel perspective on the organizational principles of complex networks. Moreover, this process is associated with two fundamentally different types of percolation transitions with a rich phase diagram. Our results shed light on the design of more resilient infrastructure networks and the effective destruction of terrorist communication networks.

  18. Articulation points in complex networks

    Science.gov (United States)

    Tian, Liang; Bashan, Amir; Shi, Da-Ning; Liu, Yang-Yu

    2017-01-01

    An articulation point in a network is a node whose removal disconnects the network. Those nodes play key roles in ensuring connectivity of many real-world networks, from infrastructure networks to protein interaction networks and terrorist communication networks. Despite their fundamental importance, a general framework of studying articulation points in complex networks is lacking. Here we develop analytical tools to study key issues pertinent to articulation points, such as the expected number of them and the network vulnerability against their removal, in an arbitrary complex network. We find that a greedy articulation point removal process provides us a different perspective on the organizational principles of complex networks. Moreover, this process results in a rich phase diagram with two fundamentally different types of percolation transitions. Our results shed light on the design of more resilient infrastructure networks and the effective destruction of terrorist communication networks.

  19. Articulation points in complex networks

    Science.gov (United States)

    Tian, Liang; Bashan, Amir; Shi, Da-Ning; Liu, Yang-Yu

    2017-01-01

    An articulation point in a network is a node whose removal disconnects the network. Those nodes play key roles in ensuring connectivity of many real-world networks, from infrastructure networks to protein interaction networks and terrorist communication networks. Despite their fundamental importance, a general framework of studying articulation points in complex networks is lacking. Here we develop analytical tools to study key issues pertinent to articulation points, such as the expected number of them and the network vulnerability against their removal, in an arbitrary complex network. We find that a greedy articulation point removal process provides us a different perspective on the organizational principles of complex networks. Moreover, this process results in a rich phase diagram with two fundamentally different types of percolation transitions. Our results shed light on the design of more resilient infrastructure networks and the effective destruction of terrorist communication networks. PMID:28139697

  20. Modeling promoter grammars with evolving hidden Markov models

    DEFF Research Database (Denmark)

    Won, Kyoung-Jae; Sandelin, Albin; Marstrand, Troels Torben

    2008-01-01

    MOTIVATION: Describing and modeling biological features of eukaryotic promoters remains an important and challenging problem within computational biology. The promoters of higher eukaryotes in particular display a wide variation in regulatory features, which are difficult to model. Often several...... factors are involved in the regulation of a set of co-regulated genes. If so, promoters can be modeled with connected regulatory features, where the network of connections is characteristic for a particular mode of regulation. RESULTS: With the goal of automatically deciphering such regulatory structures......, we present a method that iteratively evolves an ensemble of regulatory grammars using a hidden Markov Model (HMM) architecture composed of interconnected blocks representing transcription factor binding sites (TFBSs) and background regions of promoter sequences. The ensemble approach reduces the risk...

  1. [Conceptual parameters of the facial arc and articulators adapted for black Africans].

    Science.gov (United States)

    N'Dindin, A C; Djeredou, K B; N'Dindin-Guinan, B; Assi, K D

    2005-12-01

    Articulators and facial arc always used in dentistry are not adapted to African black people. Their use provokes many errors in the setting of models on articulators. In this work, authors propose facial arc and articulator parameters conceptions that are suited to black Africans.

  2. Vowel articulation in Parkinson's disease.

    Science.gov (United States)

    Skodda, Sabine; Visser, Wenke; Schlegel, Uwe

    2011-07-01

    The aim of the study was to analyze vowel articulation in Parkinson's disease (PD) speakers suffering from mild hypokinetic dysarthria as compared with healthy controls in correlation to net speech rate (NSR) and intonation variability (F(0)SD). Furthermore, we intended to reveal possible correlations among vowel articulation, global motor performance, and stage of disease. We examined 68 PD patients (34 male) with mild dysarthria (1 point according to the "speech" item 18 of the Unified Parkinson's Disease Rating Scale/UPDRS-III) and 32 age-matched control persons (16 male) using a reading task with subsequent acoustical analysis. F1 and F2 frequency values of the vowels /a/, /i/, and /u/ were extracted from defined words within the text. Description of vowel articulation was based on measures of triangular vowel space area (tVSA) and Vowel Articulation Index (VAI). PD patients were scored according to UPDRS-III and Hoehn and Yahr stages. VAI values were significantly reduced in male and female PD patients as compared with the accordant control group, whereas tVSA was only reduced in the male PD speakers. NSR was negatively correlated to tVSA and VAI only in female PD speakers. No correlations were seen between vowel articulation and UPDRS-III and stage of disease. VAI seem to be superior to tVSA in the description of impaired vowel articulation in PD. Reduced VAI could be detected in male and female parkinsonian speakers suffering only from mild dysarthria with preserved speech intelligibility and therefore might be applicable to identify subclinical changes of vowel articulation. Moreover, some aspects of altered speech performance in PD seem to feature some gender-specific patterns, which justify further investigation. Copyright © 2011 The Voice Foundation. Published by Mosby, Inc. All rights reserved.

  3. State Articulated Instructional Objectives Guide for Occupational Education Programs. State Pilot Model for Automotive Mechanics (DCC V-003) and Automotive Mechanics (High School).

    Science.gov (United States)

    North Carolina State Dept. of Community Colleges, Raleigh.

    This articulation instructional objective guide for automotive mechanics contains summary information on fifteen blocks (courses) of instruction. They are introduction to automotive technology; lubrication and vehicle operating maintenance; cooling system maintenance and repair; automobile heater maintenance and repair; braking system maintenance…

  4. 21 CFR 872.3150 - Articulator.

    Science.gov (United States)

    2010-04-01

    ... DENTAL DEVICES Prosthetic Devices § 872.3150 Articulator. (a) Identification. An articulator is a... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Articulator. 872.3150 Section 872.3150 Food and... the patient's jaws. An articulator is intended to fit dentures or provide orthodontic treatment....

  5. Modeling Potentially Time-Varying Effects of Promotions on Sales

    NARCIS (Netherlands)

    Ph.H.B.F. Franses (Philip Hans); R. Paap (Richard); Ph.A. Sijthoff

    2001-01-01

    textabstractA commonly applied modeling tool for the analysis of promotional effects on weekly sales data is a linear regression model. Usually, such a model includes 0/1 dummy variables for promotions, where weeks with a promotion get a value of 1. When these variables are included in a model with

  6. Functional occlusion: II. The role of articulators in orthodontics.

    Science.gov (United States)

    Clark, J R; Hutchinson, I; Sandy, J R

    2001-06-01

    Opinion is divided on whether there is a place for the use of semi-adjustable dental articulators in orthodontics. In this review we explore the validity and reproducibility of the techniques involved in mounting study models on a semi-adjustable dental articulator. We also look at the role of articulated study models in orthodontic diagnosis and treatment planning, in the finishing stages of orthodontics and in planning for orthognathic surgery. We report that each of the many stages involved in mounting study models on a semi-adjustable articulator is a potential source of error and that only if the technique is carried out with a high degree of accuracy is it worth the additional chairside time.

  7. The articulator: a diagnostic instrument.

    Science.gov (United States)

    Millstein, Philip L

    2002-01-01

    The success of dental restorations depends on how we view the existing occlusion. Clinicians may be confounded with what aspects of the occlusion will contribute to the success of a restoration. This information can be reviewed with the dental laboratory when it is stored in a dental articulator in the form of dental casts with simulated movements.

  8. An optimal promotion cost control model for a markovian manpower ...

    African Journals Online (AJOL)

    An optimal promotion cost control model for a markovian manpower system. ... Log in or Register to get access to full text downloads. ... A theory concerning the existence of an optimal promotion control strategy for controlling a Markovian ...

  9. Occlusion: 3. Articulators and related instruments.

    Science.gov (United States)

    Milosevic, Alex

    2003-11-01

    Dental articulators are instruments that reproduce jaw movements to varying degrees of accuracy. This article aims to give an overview of the various types of articulator and describe their applications and limitations.

  10. Parameterized trajectory generation method for passive articulated rover based on estimation of model%基于模型估计的关节式月球车参数化轨迹规划

    Institute of Scientific and Technical Information of China (English)

    禹鑫燚; 高海波; 邓宗全

    2011-01-01

    In order to improve precision of trajectory generation for rover on three dimensional rough terrain during trajectory generation phase, based on the study of passive articulated rover and D-H kinematics model method, of manipulator,this paper presented the kinematics of the suspension frame. Using this complete suspension kinematics model and the numerical solving method, it constructed the kinematical observer's estimation of passive articulated rover on arbitrary rough terrain. On the basis of this estimation of model, using principle of parameterized control, constructed an adaptive trajectory generation model for pas-sive articulated rover on arbitrary rough terrain which satisfied arbitrary constraints. According to nonholonomic characterization of the model,presented the numerical solving method of this nonlinear model. To demonstrate this trajectory generation method, presented an example about two torsion-bar rocker-bogie rover with eight wheels. Simulation results show that this trajectory method is valid for passive articulated rover on rough terrain can improve precision of trajectory generation.%为了在轨迹规划阶段提高月球车在三维地形中的轨迹规划精度,以被动关节式地形自适应月球车为研究对象,融合关节机器人D-H坐标建模方法构建月球车悬架运动学模型,结合数值求解方法,推导了任意崎岖三维地形中月球车姿态估计模型.在模型估计基础上利用参数化控制原理,建立了满足约束条件下被动关节式月球车在任意地形中的基于模型估计的一般性参数化轨迹生成模型.针对轮式月球车的非完整性特点,结合数值求解方法,推导了非线性模型的求解方法.最后利用仿真方法,以八轮摇杆摇臂关节式月球车为例,验证了崎岖地形中基于模型估计的轨迹生成方法的正确性,且可提高关节式月球车在崎岖地形中的规划精度.

  11. FCC in Viking articulated boom

    Science.gov (United States)

    Hawkins, E. S.

    1972-01-01

    The application requirements and manufacturing techniques for the flat conductor cable used in the Viking Lander Articulated Boom Unit are described. The Viking Boom is a 3-axis device utilized to position a soil sampler and provide digging forces. This application imposed severe restrictions on size, weight, materials, and choice of manufacturing processes. The final cable assembly design resulted in a combination of collated cable and flexible circuits assembled by resistance welding techniques.

  12. Kinematics and Path Following Control of an Articulated Drum Roller

    Science.gov (United States)

    BIAN, Yongming; YANG, Meng; FANG, Xiaojun; WANG, Xiahui

    2017-07-01

    Automatic navigation of an articulated drum roller, which is an articulated steering type vehicle widely used in the construction industry, is highly expected for operation cost reduction and improvement of work efficiency. In order to achieve the path following control, considering that its steering system is articulated steering and two frames are articulated by an active revolute joint, a kinematic model and an error dynamic state-space equation of an articulated drum roller are proposed. Besides, a state-feedback control law based on Lyapunov stability theory is also designed, which can be proved to achieve the purpose of control by the analysis of stability. What's more, to evaluate the performance of the proposed method, simulation under the MATLAB/Simulink and experiments using positioning algorithm and errors correction at the uneven construction site are performed, with initial displacement error (-1.5 m), heading error (-0.11 rad) and steering angle (-0.19 rad). Finally, simulation and experimental results show that the errors and steering angle can decrease gradually, and converge to zero with time. Meanwhile, the control input is not saturated. An articulated drum roller can lock into a desired path with the proposed method in uneven fields.

  13. 21 CFR 872.6140 - Articulation paper.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Articulation paper. 872.6140 Section 872.6140 Food... DEVICES DENTAL DEVICES Miscellaneous Devices § 872.6140 Articulation paper. (a) Identification. Articulation paper is a device composed of paper coated with an ink dye intended to be placed between the...

  14. Active steering control strategy for articulated vehicles

    Institute of Scientific and Technical Information of China (English)

    Kyong-il KIM; Hsin GUAN; Bo WANG; Rui GUO; Fan LIANG

    2016-01-01

    To improve maneuverability and stability of articulated vehicles, we design an active steering controller, including tractor and trailer controllers, based on linear quadratic regulator (LQR) theory. First, a three-degree-of-freedom (3-DOF) model of the tractor-trailer with steered trailer axles is built. The simulated annealing particle swarm optimization (SAPSO) algorithm is applied to identify the key parameters of the model under specified vehicle speed and steering wheel angle. Thus, the key pa-rameters of the simplified model can be obtained according to the vehicle conditions using an online look-up table and interpola-tion. Simulation results show that vehicle parameter outputs of the simplified model and TruckSim agree well, thus providing the ideal reference yaw rate for the controller. Then the active steering controller of the tractor and trailer based on LQR is designed to follow the desired yaw rate and minimize their side-slip angle of the center of gravity (CG) at the same time. Finally, simulation tests at both low speed and high speed are conducted based on the TruckSim-Simulink program. The results show significant effects on the active steering controller on improving maneuverability at low speed and lateral stability at high speed for the articulated vehicle. The control strategy is applicable for steering not only along gentle curves but also along sharp curves.

  15. VARIATIONAL MONTE-CARLO APPROACH FOR ARTICULATED OBJECT TRACKING

    Directory of Open Access Journals (Sweden)

    Kartik Dwivedi

    2013-12-01

    Full Text Available In this paper, we describe a novel variational Monte Carlo approach for modeling and tracking body parts of articulated objects. An articulated object (human target is represented as a dynamic Markov network of the different constituent parts. The proposed approach combines local information of individual body parts and other spatial constraints influenced by neighboring parts. The movement of the relative parts of the articulated body is modeled with local information of displacements from the Markov network and the global information from other neighboring parts. We explore the effect of certain model parameters (including the number of parts tracked; number of Monte-Carlo cycles, etc. on system accuracy and show that ourvariational Monte Carlo approach achieves better efficiency and effectiveness compared to other methods on a number of real-time video datasets containing single targets.

  16. Evaluation of an improved orthognathic articulator system: 1. Accuracy of cast orientation.

    Science.gov (United States)

    Paul, P E; Barbenel, J C; Walker, F S; Khambay, B S; Moos, K F; Ayoub, A F

    2012-02-01

    A systematic study was carried out using plastic model skulls to quantify the accuracy of the transfer of face bow registration to the articulator. A standard Dentatus semi-adjustable articulator system was compared to a purpose built orthognathic articulator system by measuring the maxillary occlusal plane angles of plastic model skulls and of dental casts mounted on the two different types of articulators. There was a statistically significant difference between the two systems; the orthognathic system showed small random errors, but the standard system showed systematic errors of up to 28°.

  17. The Nexus Land-Use model version 1.0, an approach articulating biophysical potentials and economic dynamics to model competition for land-use

    Directory of Open Access Journals (Sweden)

    F. Souty

    2012-02-01

    Full Text Available Interactions between food demand, biomass energy and forest preservation are driving both food prices and land-use changes, regionally and globally. This study presents a new model called Nexus Land-Use version 1.0 which describes these interactions through a generic representation of agricultural intensification mechanisms. The Nexus Land-Use model equations combine biophysics and economics into a single coherent framework to calculate crop yields, food prices, and resulting pasture and cropland areas within 12 regions inter-connected with each other by international trade. The representation of cropland and livestock production systems in each region relies on three components: (i a biomass production function derived from the crop yield response function to inputs such as industrial fertilisers; (ii a detailed representation of the livestock production system subdivided into an intensive and an extensive component, and (iii a spatially explicit distribution of potential (maximal crop yields prescribed from the Lund-Postdam-Jena global vegetation model for managed Land (LPJmL. The economic principles governing decisions about land-use and intensification are adapted from the Ricardian rent theory, assuming cost minimisation for farmers. The land-use modelling approach described in this paper entails several advantages. Firstly, it makes it possible to explore interactions among different types of biomass demand for food and animal feed, in a consistent approach, including indirect effects on land-use change resulting from international trade. Secondly, yield variations induced by the possible expansion of croplands on less suitable marginal lands are modelled by using regional land area distributions of potential yields, and a calculated boundary between intensive and extensive production. The model equations and parameter values are first described in details. Then, idealised scenarios exploring the impact of forest preservation policies or

  18. 仿人小脑神经网络结构的驾驶员方向控制行为建模%Modeling of Driver's Directional Control Behavior with Cerebellar Model Articulation Controller

    Institute of Scientific and Technical Information of China (English)

    高振海; 段立飞

    2012-01-01

    After analyzing the characteristics of driver movement control behavior, a humanoid cerebellum neural network control model for driver's directional control behavior is established with cerebellar model articulation controller to conduct the control error correction on conventional differential correction model. The results of simulation under different vehicle speed, road geometry and adhesion coefficients show that the control algorithm proposed has high path tracking accuracy as well as the adaptability and robustness to the dynamic uncertainty factors in vehicle speed and road conditions%在分析驾驶员的运动控制行为特性基础上,仿照人小脑神经网络结构,建立了驾驶员对汽车方向控制行为的小脑神经网络控制模型,以此对传统的微分校正模型进行控制误差修正.在不同车速、路形和路面附着系数下的仿真结果表明,所提出的控制算法有高的路径跟踪精度,且对车速和道路状况等汽车行驶过程中的动态不确定性因素具有较强的适应性和鲁棒性.

  19. The Nexus Land-Use model version 1.0, an approach articulating biophysical potentials and economic dynamics to model competition for land-use

    Directory of Open Access Journals (Sweden)

    F. Souty

    2012-10-01

    Full Text Available Interactions between food demand, biomass energy and forest preservation are driving both food prices and land-use changes, regionally and globally. This study presents a new model called Nexus Land-Use version 1.0 which describes these interactions through a generic representation of agricultural intensification mechanisms within agricultural lands. The Nexus Land-Use model equations combine biophysics and economics into a single coherent framework to calculate crop yields, food prices, and resulting pasture and cropland areas within 12 regions inter-connected with each other by international trade. The representation of cropland and livestock production systems in each region relies on three components: (i a biomass production function derived from the crop yield response function to inputs such as industrial fertilisers; (ii a detailed representation of the livestock production system subdivided into an intensive and an extensive component, and (iii a spatially explicit distribution of potential (maximal crop yields prescribed from the Lund-Postdam-Jena global vegetation model for managed Land (LPJmL. The economic principles governing decisions about land-use and intensification are adapted from the Ricardian rent theory, assuming cost minimisation for farmers. In contrast to the other land-use models linking economy and biophysics, crops are aggregated as a representative product in calories and intensification for the representative crop is a non-linear function of chemical inputs. The model equations and parameter values are first described in details. Then, idealised scenarios exploring the impact of forest preservation policies or rising energy price on agricultural intensification are described, and their impacts on pasture and cropland areas are investigated.

  20. The Nexus Land-Use model version 1.0, an approach articulating biophysical potentials and economic dynamics to model competition for land-use

    Science.gov (United States)

    Souty, F.; Brunelle, T.; Dumas, P.; Dorin, B.; Ciais, P.; Crassous, R.; Müller, C.; Bondeau, A.

    2012-10-01

    Interactions between food demand, biomass energy and forest preservation are driving both food prices and land-use changes, regionally and globally. This study presents a new model called Nexus Land-Use version 1.0 which describes these interactions through a generic representation of agricultural intensification mechanisms within agricultural lands. The Nexus Land-Use model equations combine biophysics and economics into a single coherent framework to calculate crop yields, food prices, and resulting pasture and cropland areas within 12 regions inter-connected with each other by international trade. The representation of cropland and livestock production systems in each region relies on three components: (i) a biomass production function derived from the crop yield response function to inputs such as industrial fertilisers; (ii) a detailed representation of the livestock production system subdivided into an intensive and an extensive component, and (iii) a spatially explicit distribution of potential (maximal) crop yields prescribed from the Lund-Postdam-Jena global vegetation model for managed Land (LPJmL). The economic principles governing decisions about land-use and intensification are adapted from the Ricardian rent theory, assuming cost minimisation for farmers. In contrast to the other land-use models linking economy and biophysics, crops are aggregated as a representative product in calories and intensification for the representative crop is a non-linear function of chemical inputs. The model equations and parameter values are first described in details. Then, idealised scenarios exploring the impact of forest preservation policies or rising energy price on agricultural intensification are described, and their impacts on pasture and cropland areas are investigated.

  1. Computer programs for the calculation of dual sting pitch and roll angles required for an articulated sting to obtain angles of attack and sideslip on wind-tunnel models

    Science.gov (United States)

    Peterson, John B., Jr.

    1991-01-01

    Two programs were developed to calculate the pitch and roll position of the conventional sting drive and the pitch of a high angle articulated sting to position a wind tunnel model at the desired angle of attack and sideslip and position the model as near as possible to the centerline of the tunnel. These programs account for the effects of sting offset angles, sting bending angles, and wind-tunnel stream flow angles. In addition, the second program incorporates inputs form on-board accelerometers that measure model pitch and roll with respect to gravity. The programs are presented and a description of the numerical operation of the programs with a definition of the variables used in the programs is given.

  2. 一个三维人膝关节弹性咬合的生物力学模型%A 3-D BIOMECHANICAL MODEL OF HUMAN KNEE JOINT ELASTICALLY ARTICULATE CONTACT

    Institute of Scientific and Technical Information of China (English)

    王西十; 王珉

    2000-01-01

    Based on the characterizations of human knee-joint anatomical structures and reports of the literature and experiments, a 3-D biomechanical model of the human knee-joint elastically articulate contact is developed under the conditions of sampling the human knee-joints. This model is believed to be a powerful tool for functional analysis of the knee, for evaluation of surgical and diagnostic procedures and for design of artificial joints.%基于人膝关节的解剖特征,在文献和试验的基础上,对膝关节解剖结构作了适当的简化,从而建立了一个完整的三维人膝关节弹性咬合的生物力学模型.

  3. Optimization of Front Axle Suspension System of Articulated Dump Truck

    DEFF Research Database (Denmark)

    Langer, Thomas Heegaard; Christensen, Brian B.; Mouritsen, Ole Ø.

    2010-01-01

    ongoing research collaboration between Hydrema Produktion A/S, Aalborg University and the University of Agder on comfort improvement. The main goal of the research project is to improve ride comfort of articulated construction machinery by use of multibody simulation models. In this paper the application...... that has been subjected to comfort improvement is a two axle articulated dump truck. The comfort has been in terms of whole body vibration exposure and the overall improvement has been made possible by adding front axle suspension. However, a hydraulic stabilizing system between the tractor and trailer...

  4. A maximum likelihood approach to estimating articulator positions from speech acoustics

    Energy Technology Data Exchange (ETDEWEB)

    Hogden, J.

    1996-09-23

    This proposal presents an algorithm called maximum likelihood continuity mapping (MALCOM) which recovers the positions of the tongue, jaw, lips, and other speech articulators from measurements of the sound-pressure waveform of speech. MALCOM differs from other techniques for recovering articulator positions from speech in three critical respects: it does not require training on measured or modeled articulator positions, it does not rely on any particular model of sound propagation through the vocal tract, and it recovers a mapping from acoustics to articulator positions that is linearly, not topographically, related to the actual mapping from acoustics to articulation. The approach categorizes short-time windows of speech into a finite number of sound types, and assumes the probability of using any articulator position to produce a given sound type can be described by a parameterized probability density function. MALCOM then uses maximum likelihood estimation techniques to: (1) find the most likely smooth articulator path given a speech sample and a set of distribution functions (one distribution function for each sound type), and (2) change the parameters of the distribution functions to better account for the data. Using this technique improves the accuracy of articulator position estimates compared to continuity mapping -- the only other technique that learns the relationship between acoustics and articulation solely from acoustics. The technique has potential application to computer speech recognition, speech synthesis and coding, teaching the hearing impaired to speak, improving foreign language instruction, and teaching dyslexics to read. 34 refs., 7 figs.

  5. Characterization of prokaryotic and eukaryotic promoters usinghidden Markov models

    DEFF Research Database (Denmark)

    Pedersen, Anders Gorm; Baldi, Pierre; Brunak, Søren

    1996-01-01

    that bind to them. We find that HMMs trained on such subclasses of Escherichia coli promoters (specifically, the so-called sigma-70 and sigma-54 classes) give an excellent classification of unknown promoters with respect to sigma-class. HMMs trained on eukaryotic sequences from human genes also model nicely......In this paper we utilize hidden Markov models (HMMs) and information theory to analyze prokaryotic and eukaryotic promoters. We perform this analysis with special emphasis on the fact that promoters are divided into a number of different classes, depending on which polymerase-associated factors...... have at the same time the ability to find clusters and the ability to model the sequential structure in the input data. This is highly relevant in situations where the variance in the data is high, as is the case for the subclass structure in for example promoter sequences....

  6. Characterization of prokaryotic and eukaryotic promoters using hidden Markov models

    DEFF Research Database (Denmark)

    Pedersen, Anders Gorm; Baldi, P.; Chauvin, Y.

    1996-01-01

    that bind to them. We find that HMMs trained on such subclasses of Escherichia coli promoters (specifically, the so-called sigma 70 and sigma 54 classes) give an excellent classification of unknown promoters with respect to sigma-class. HMMs trained on eukaryotic sequences from human genes also model nicely......In this paper we utilize hidden Markov models (HMMs) and information theory to analyze prokaryotic and eukaryotic promoters. We perform this analysis with special emphasis on the fact that promoters are divided into a number of different classes, depending on which polymerase-associated factors...... have at the same time the ability to find clusters and the ability to model the sequential structure in the input data. This is highly relevant in situations where the variance in the data is high, as is the case for the subclass structure in for example promoter sequences....

  7. Dynamics of an advertising competition model with sales promotion

    Science.gov (United States)

    Jiang, Hui; Feng, Zhaosheng; Jiang, Guirong

    2017-01-01

    In this paper, an advertising competition model with sales promotion is constructed and investigated. Conditions of the existence and stability of period-T solutions are obtained by means of the discrete map. Flip bifurcation is analyzed by using the center manifold theory and three sales promotion strategies are discussed. Example and numerical simulations are illustrated which agree well with our theoretical analysis.

  8. Application of Health Promotion Theories and Models for Environmental Health

    Science.gov (United States)

    Parker, Edith A.; Baldwin, Grant T.; Israel, Barbara; Salinas, Maria A.

    2004-01-01

    The field of environmental health promotion gained new prominence in recent years as awareness of physical environmental stressors and exposures increased in communities across the country and the world. Although many theories and conceptual models are used routinely to guide health promotion and health education interventions, they are rarely…

  9. GPU Accelerated Likelihoods for Stereo-Based Articulated Tracking

    DEFF Research Database (Denmark)

    Friborg, Rune Møllegaard; Hauberg, Søren; Erleben, Kenny

    For many years articulated tracking has been an active research topic in the computer vision community. While working solutions have been suggested, computational time is still problematic. We present a GPU implementation of a ray-casting based likelihood model that is orders of magnitude faster...

  10. Stick it! Articulated tracking using spatial rigid object priors

    DEFF Research Database (Denmark)

    Hauberg, Søren; Pedersen, Kim Steenstrup

    2010-01-01

    Articulated tracking of humans is a well-studied field, but most work has treated the humans as being independent of the environment. Recently, Kjellstrom et al. showed how knowledge of interaction with a known rigid object provides constraints that lower the degrees of freedom in the model. While...

  11. GPU accelerated likelihoods for stereo-based articulated tracking

    DEFF Research Database (Denmark)

    Friborg, Rune Møllegaard; Hauberg, Søren; Erleben, Kenny

    2010-01-01

    For many years articulated tracking has been an active research topic in the computer vision community. While working solutions have been suggested, computational time is still problematic. We present a GPU implementation of a ray-casting based likelihood model that is orders of magnitude faster...

  12. Closed-loop analysis of an articulated railcar train

    Energy Technology Data Exchange (ETDEWEB)

    Heinzl, P.; Ploechl, M.; Mack, W.; Lugner, P. [Technische Univ., Vienna (Austria). Inst. fuer Mechanik

    2000-07-01

    An articulated railcar train is modelled by a plane three-body linkage mechanism guided at two points along a given trajectory with a prescribed velocity of the front point. The closed-loop system is analyzed using a symbolic-numerical method leading to ordinary differential equations in minimal coordinates. (orig.)

  13. Articulation for Elementary School Foreign Language Programs: Challenges and Opportunities.

    Science.gov (United States)

    Pesola, Carol Ann

    While foreign language instruction for elementary school children is gaining attention, poor articulation is a problem that has become more complex because of the variety of foreign language program models being developed. Five main types are in use: total immersion, partial immersion, foreign languages in the elementary school (FLES),…

  14. Articulation effects in melody recognition memory.

    Science.gov (United States)

    Wee Hun Lim, Stephen; Goh, Winston D

    2013-09-01

    Various surface features-timbre, tempo, and pitch-influence melody recognition memory, but articulation format effects, if any, remain unknown. For the first time, these effects were examined. In Experiment 1, melodies that remained in the same, or appeared in a different but similar, articulation format from study to test were recognized better than were melodies that were presented in a distinct format at test. A similar articulation format adequately induced matching processes to enhance recognition. Experiment 2 revealed that melodies rated as perceptually dissimilar on the basis of the location of the articulation mismatch did not impair recognition performance, suggesting an important boundary condition for articulation format effects on memory recognition-the matching of the memory trace and recognition probe may depend more on the overall proportion, rather than the temporal location, of the mismatch. The present findings are discussed in terms of a global matching advantage hypothesis.

  15. Measurement accuracy of articulated arm CMMs with circular grating eccentricity errors

    Science.gov (United States)

    Zheng, Dateng; Yin, Sanfeng; Luo, Zhiyang; Zhang, Jing; Zhou, Taiping

    2016-11-01

    The 6 circular grating eccentricity errors model attempts to improve the measurement accuracy of an articulated arm coordinate measuring machine (AACMM) without increasing the corresponding hardware cost. We analyzed the AACMM’s circular grating eccentricity and obtained the 6 joints’ circular grating eccentricity error model parameters by conducting circular grating eccentricity error experiments. We completed the calibration operations for the measurement models by using home-made standard bar components. Our results show that the measurement errors from the AACMM’s measurement model without and with circular grating eccentricity errors are 0.0834 mm and 0.0462 mm, respectively. Significantly, we determined that measurement accuracy increased by about 44.6% when the circular grating eccentricity errors were corrected. This study is significant because it promotes wider applications of AACMMs both in theory and in practice.

  16. Data and Model Integration Promoting Interdisciplinarity

    Science.gov (United States)

    Koike, T.

    2014-12-01

    It is very difficult to reflect accumulated subsystem knowledge into holistic knowledge. Knowledge about a whole system can rarely be introduced into a targeted subsystem. In many cases, knowledge in one discipline is inapplicable to other disciplines. We are far from resolving cross-disciplinary issues. It is critically important to establish interdisciplinarity so that scientific knowledge can transcend disciplines. We need to share information and develop knowledge interlinkages by building models and exchanging tools. We need to tackle a large increase in the volume and diversity of data from observing the Earth. The volume of data stored has exponentially increased. Previously, almost all of the large-volume data came from satellites, but model outputs occupy the largest volume in general. To address the large diversity of data, we should develop an ontology system for technical and geographical terms in coupling with a metadata design according to international standards. In collaboration between Earth environment scientists and IT group, we should accelerate data archiving by including data loading, quality checking and metadata registration, and enrich data-searching capability. DIAS also enables us to perform integrated research and realize interdisciplinarity. For example, climate change should be addressed in collaboration between the climate models, integrated assessment models including energy, economy, agriculture, health, and the models of adaptation, vulnerability, and human settlement and infrastructure. These models identify water as central to these systems. If a water expert can develop an interrelated system including each component, the integrated crisis can be addressed by collaboration with various disciplines. To realize this purpose, we are developing a water-related data- and model-integration system called a water cycle integrator (WCI).

  17. Models for financing the regulation of pharmaceutical promotion.

    Science.gov (United States)

    Lexchin, Joel

    2012-07-11

    Pharmaceutical companies spend huge sums promoting their products whereas regulation of promotional activities is typically underfinanced. Any option for financing the monitoring and regulation of promotion should adhere to three basic principles: stability, predictability and lack of (perverse) ties between the level of financing and performance. This paper explores the strengths and weaknesses of six different models. All these six models considered here have positive and negative features and none may necessarily be ideal in any particular country. Different countries may choose to utilize a combination of two or more of these models in order to raise sufficient revenue. Financing of regulation of drug promotion should more than pay for itself through the prevention of unnecessary drug costs and the avoidance of adverse health effects due to inappropriate prescribing. However, it involves an initial outlay of money that is currently not being spent and many national governments, in both rich and poor countries, are unwilling to incur extra costs.

  18. Models for financing the regulation of pharmaceutical promotion

    Directory of Open Access Journals (Sweden)

    Lexchin Joel

    2012-07-01

    Full Text Available Abstract Pharmaceutical companies spend huge sums promoting their products whereas regulation of promotional activities is typically underfinanced. Any option for financing the monitoring and regulation of promotion should adhere to three basic principles: stability, predictability and lack of (perverse ties between the level of financing and performance. This paper explores the strengths and weaknesses of six different models. All these six models considered here have positive and negative features and none may necessarily be ideal in any particular country. Different countries may choose to utilize a combination of two or more of these models in order to raise sufficient revenue. Financing of regulation of drug promotion should more than pay for itself through the prevention of unnecessary drug costs and the avoidance of adverse health effects due to inappropriate prescribing. However, it involves an initial outlay of money that is currently not being spent and many national governments, in both rich and poor countries, are unwilling to incur extra costs.

  19. Pronunciation and Articulation for Singing Chinese Works

    Institute of Scientific and Technical Information of China (English)

    郑菲菲

    2013-01-01

    For singing Chinese works, pronunciation and articulation are the most essential and the most crucial factors. Their beginning should be brief, middle should be melodious and long-lasting, and end should be as clear and crisp as crystal. Considering from pronunciations, Chinese works can be divided into two categories:one is comprehensive style emphasizing clear enunciation; the other is local folk song that should be sung based on corresponding local accent of the works. Besides, based on correct pronunciation and articulation, balance between pro-nunciation and articulation should be achieved, both the essence of western traditional mode of singing and Chinese traditional music should be followed and inherited.

  20. Design Articulations for Aesthetics of Interaction

    DEFF Research Database (Denmark)

    Petersen, Marianne Graves; Krogh, Peter

    2009-01-01

    In this paper we present three categories of design articulations addressing the characteristic qualities of aesthetics of interaction. By aesthetics of interaction we point to the process in which interactive technology brings about aesthetic experience in the use of interactive technology...... in everyday life. As designers we are prohibited access to the aesthetic experience of the user. However, we have the possibility of articulating intentions and values embedded in the artefact that can be interpreted in use and thereby providing the artefact an aesthetic potential for users to unleash. Design...... articulations serve as catalysts for developing and choosing design expressions in the design process. Design articulations are embodied in artifacts, that address desired, anticipated or identified user experiences and capabilities, carrying a format which enable discussions also with non...

  1. Unscented Kalman filtering for articulated human tracking

    DEFF Research Database (Denmark)

    Boesen Lindbo Larsen, Anders; Hauberg, Søren; Pedersen, Kim Steenstrup

    2011-01-01

    We present an articulated tracking system working with data from a single narrow baseline stereo camera. The use of stereo data allows for some depth disambiguation, a common issue in articulated tracking, which in turn yields likelihoods that are practically unimodal. While current state...... with superior results. Tracking quality is measured by comparing with ground truth data from a marker-based motion capture system....

  2. Reaction torque minimization techniques for articulated payloads

    Science.gov (United States)

    Kral, Kevin; Aleman, Roberto M.

    1988-01-01

    Articulated payloads on spacecraft, such as antenna telemetry systems and robotic elements, impart reaction torques back into the vehicle which can significantly affect the performance of other payloads. This paper discusses ways to minimize the reaction torques of articulated payloads through command-shaping algorithms and unique control implementations. The effects of reaction torques encountered on Landsat are presented and compared with simulated and measured data of prototype systems employing these improvements.

  3. 一个人膝关节弹性咬合接触的生物力学模型%A Biomechanical Model of Human Knee-Joint Elastic Articulate Contact

    Institute of Scientific and Technical Information of China (English)

    王西十; TurgutTumer; 等

    2001-01-01

    In this paper, based on the characterizations of human knee-joint anatomical structures and reports of the literature and experiments, a biomechanical model of the human knee-joint elastic articulate contact is developed under the conditions of sampling the human knee-joints. This model is believed to be a powerful tool for functional analysis of the knee, for evaluation of surgical and diagnostic procedures and for design of artificial joints.%基于人膝关节的解剖特征,在文献和试验的基础上,对膝关节解剖结构作了适当的简化,从而根据赫茨理论,建立了膝关节股骨与胫骨弹性咬合接触的生物力学模型,并获得了膝关节弹性咬合接触的最大咬合接触应力、咬合接触面积和相对咬合接触变形的定解形式。这些解的结果,对于指导临床诊断和治疗膝关节病等均具有重要作用。

  4. A behavioural modelling approach to curriculum development and evaluation of health promotion for nurses.

    Science.gov (United States)

    Kelly, M P; Maloney, W A

    1992-05-01

    This paper outlines the way in which two behavioural science models may be used in the processes of curriculum development and course evaluation. The models are the stress-coping paradigm associated with the work of Lazarus and the theory of self and identity developed from the work of Mead. It is suggested that a clear articulation of the underlying behavioural processes is fundamental in course design and appraisal.

  5. Accurate recovery of articulator positions from acoustics: New conclusions based on human data

    Energy Technology Data Exchange (ETDEWEB)

    Hogden, J. [MS B265, Los Alamos National Laboratory, Los Alamos, New Mexico 87545 (United States); Lofqvist, A.; Gracco, V. [Haskins Laboratories, 270 Crown Street, New Haven, Connecticut 06511 (United States); Zlokarnik, I. [MS B265, Los Alamos National Laboratory, Los Alamos, New Mexico 87545 (United States); Rubin, P.; Saltzman, E. [Haskins Laboratories, 270 Crown Street, New Haven, Connecticut 06511 (United States)

    1996-09-01

    Vocal tract models are often used to study the problem of mapping from the acoustic transfer function to the vocal tract area function (inverse mapping). Unfortunately, results based on vocal tract models are strongly affected by the assumptions underlying the models. In this study, the mapping from acoustics (digitized speech samples) to articulation (measurements of the positions of receiver coils placed on the tongue, jaw, and lips) is examined using human data from a single speaker: Simultaneous acoustic and articulator measurements made for vowel-to-vowel transitions, /g/ closures, and transitions into and out of /g/ closures. Articulator positions were measured using an EMMA system to track coils placed on the lips, jaw, and tongue. Using these data, look-up tables were created that allow articulator positions to be estimated from acoustic signals. On a data set not used for making look-up tables, correlations between estimated and actual coil positions of around 94{percent} and root-mean-squared errors around 2 mm are common for coils on the tongue. An error source evaluation shows that estimating articulator positions from quantized acoustics gives root-mean-squared errors that are typically less than 1 mm greater than the errors that would be obtained from quantizing the articulator positions themselves. This study agrees with and extends previous studies of human data by showing that for the data studied, speech acoustics can be used to accurately recover articulator positions. {copyright} {ital 1996 Acoustical Society of America.}

  6. [Semi-adjustable articulator for computer aided design of complete denture].

    Science.gov (United States)

    Sun, Yu-Chun; L V, Pei-Jun; Wang, Yong

    2008-02-18

    To explore virtual semi-adjustable articulator for complete denture computer aided design (CAD) system, and to simulate biting motion and virtual occlusal adjustment for a complete denture CAD digital model. The edentulous jaw casts, rims and bite records of forward protrusion were made in clinic. The casts were fixed to the articulator and inclination of protrusive condylar guidance was set up with bite records of forward protrusion. Inclination of lateral condylar guidance was calculated and set up with Hanus formula. Inclination of protrusive incisal guidance inclination was calculated and set up with ratios of over bite and overjet of complete denture CAD digital model which have been designed with Complete Denture CAD System. The 3D locus data of semi-adjustable articulator was obtained by scanning three points on articulator with contact head of FARO ScanArm (FARO Technologies Inc., American). In the same scanning coordinate system, the laser scanner was used to get labial/buccal surface data of rims at centric relation position. Based on rims, the coordinate system was set up and the complete denture CAD model was aligned to the locus data. The virtual articulator program was explored with Scoll language offered by Imageware (EDS corp., American). The 3D biting motion simulating, automatic occluding relation detection and automatic occlusal adjustment functions were supported by the program. A virtual semi-adjustable articulator program for Complete Denture CAD System was explored and applied to a complete denture CAD digital model. With the program, 3D biting motion simulating, automatic occluding relation detection and automatic occlusal adjustment can be realized. A technical route of virtual articulator is set up based on semi-adjustable articulator and initial approach is carried out for application of the virtual articulator in CAD progress of complete denture.

  7. Varying parameter models to accommodate dynamic promotion effects

    NARCIS (Netherlands)

    Foekens, E.W.; Leeflang, P.S.H.; Wittink, D.R.

    1999-01-01

    The purpose of this paper is to examine the dynamic effects of sales promotions. We create dynamic brand sales models (for weekly store-level scanner data) by relating store intercepts and a brand's own price elasticity to a measure of the cumulated previous price discounts - amount and time - for t

  8. A Contemporary Leadership Model to Promote Teacher Leadership.

    Science.gov (United States)

    Bishop, Harold L.; Tinley, Alice; Berman, Barbara T.

    1997-01-01

    Presents a contemporary leadership model comprised of three elements necessary to successfully recognize and promote teacher leaders. The elements include establishing an appropriate school culture, recognizing teacher leaders, and inspiring teachers' confidence. The three elements, along with enabled teacher leadership, create positive cultural…

  9. MODEL2TALK: An Intervention to Promote Productive Classroom Talk

    Science.gov (United States)

    van der Veen, Chiel; van der Wilt, Femke; van Kruistum, Claudia; van Oers, Bert; Michaels, Sarah

    2017-01-01

    This article describes the MODEL2TALK intervention, which aims to promote young children's oral communicative competence through productive classroom talk. Productive classroom talk provides children in early childhood education with many opportunities to talk and think together. Results from a large-scale study show that productive classroom talk…

  10. STAS and Logit Modeling of Advertising and Promotion Effects

    DEFF Research Database (Denmark)

    Hansen, Flemming; Yssing Hansen, Lotte; Grønholdt, Lars

    2002-01-01

    This paper describes the preliminary studies of the effect of advertising and promotion on purchases using the British single-source database Adlab. STAS and logit modeling are the two measures studied. Results from the two measures have been compared to determine the extent to which, they give...

  11. Varying parameter models to accommodate dynamic promotion effects

    NARCIS (Netherlands)

    Foekens, E.W.; Leeflang, P.S.H.; Wittink, D.R.

    1999-01-01

    The purpose of this paper is to examine the dynamic effects of sales promotions. We create dynamic brand sales models (for weekly store-level scanner data) by relating store intercepts and a brand's own price elasticity to a measure of the cumulated previous price discounts - amount and time - for

  12. Promoting Continuous Quality Improvement in Online Teaching: The META Model

    Science.gov (United States)

    Dittmar, Eileen; McCracken, Holly

    2012-01-01

    Experienced e-learning faculty members share strategies for implementing a comprehensive postsecondary faculty development program essential to continuous improvement of instructional skills. The high-impact META Model (centered around Mentoring, Engagement, Technology, and Assessment) promotes information sharing and content creation, and fosters…

  13. [The controversy of routine articulator mounting in orthodontics].

    Science.gov (United States)

    Wang, Li; Han, Xianglong; Bai, Ding

    2013-06-01

    Articulators have been widely used by clinicians of dentistry. But routine articulator mounting is still controversial in orthodontics. Orthodontists oriented by gnathology approve routine articulator mounting while nongnathologic orthodontists disapprove it. This article reviews the thoughts of orthodontist that they agree or disagree with routine articulator mounting based on the considerations of biting, temporomandibular disorder (TMD), periodontitis, and so on.

  14. State Estimation of the Electric Drive Articulated Dump Truck Based on UKF

    Institute of Scientific and Technical Information of China (English)

    Chun Jin; Tong Liu; Yanhua Shen

    2015-01-01

    The requirements of vehicle dynamic stability control are higher than ever as the significant increase of electric drive articulated vehicle speed. According to the construction features of articulated dumping truck and nonlinear characteristics of moving vehicles, nonlinear observer of vehicle status is designed to strength robustness of dynamic control system in this paper. A 4⁃degree⁃of⁃freedom nonlinear dynamic model of articulated electric drive vehicle is built as reference model to estimate the state of the articulated vehicle. And by adopting Unscented Kalman Filter ( UKF ) algorithm, a series of state parameters such as longitudinal velocities of front and rear frames, yaw rate and side⁃slip angle are estimated. During the test of 60 t articulated electric drive vehicle, 2 inertial navigation modules are installed in the front frame and rear frame respectively and the speed of each electric drive wheel is obtained simultaneously. As the test results suggest, in various working conditions, the algorithm based on UKF is able to accurately estimate the state parameters of articulated vehicle with the estimated error less than 5%. The proposed method is justified to be the theoretical basis and application guidance for articulated vehicle stability control.

  15. Open software architecture for east articulated maintenance arm

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Jing, E-mail: wujing@ipp.ac.cn [Institute of Plasma Physics Chinese Academy of Sciences, 350 Shushanhu Rd Hefei Anhui (China); Lappeenranta University of Technology, Skinnarilankatu 34 Lappeenranta (Finland); Wu, Huapeng [Lappeenranta University of Technology, Skinnarilankatu 34 Lappeenranta (Finland); Song, Yuntao [Institute of Plasma Physics Chinese Academy of Sciences, 350 Shushanhu Rd Hefei Anhui (China); Li, Ming [Lappeenranta University of Technology, Skinnarilankatu 34 Lappeenranta (Finland); Yang, Yang [Institute of Plasma Physics Chinese Academy of Sciences, 350 Shushanhu Rd Hefei Anhui (China); Alcina, Daniel A.M. [Lappeenranta University of Technology, Skinnarilankatu 34 Lappeenranta (Finland)

    2016-11-01

    Highlights: • A software requirement of serial-articulated robot for EAST assembly and maintains is presented. • A open software architecture of the robot is developed. • A component-based model distribution system with real-time communication of the robot is constructed. - Abstract: For the inside inspection and the maintenance of vacuum vessel in the EAST, an articulated maintenance arm is developed. In this article, an open software architecture developed for the EAST articulated maintenance arm (EAMA) is described, which offers a robust and proper performance and easy-going experience based on standard open robotic platform OROCOS. The paper presents a component-based model software architecture using multi-layer structure: end layer, up layer, middle, and down layer. In the end layer the components are defined off-line in the task planner manner. The components in up layer complete the function of trajectory plan. The CORBA, as a communication framework, is adopted to exchange the data between the distributed components. The contributors use Real-Time Workshop from the MATLAB/Simulink to generate the components in the middle layer. Real-time Toolkit guarantees control applications running in the hard real-time mode. Ethernets and the CAN bus are used for data transfer in the down layer, where the components implement the hardware functions. The distributed architecture of control system associates each processing node with each joint, which is mapped to a component with all functioning features of the framework.

  16. A Pervasive Promotion Model for Personalized Promotion Systems on Using WLAN Localization and NFC Techniques

    Directory of Open Access Journals (Sweden)

    Kam-Yiu Lam

    2015-01-01

    Full Text Available In this paper, we propose a novel pervasive business model for sales promotion in retail chain stores utilizing WLAN localization and near field communication (NFC technologies. The objectives of the model are to increase the customers’ flow of the stores and their incentives in purchasing. In the proposed model, the NFC technology is used as the first mean to motivate customers to come to the stores. Then, with the use of WLAN, the movements of the customers, who are carrying smartphones, within the stores are captured and maintained in the movement database. By interpreting the movements of customers as indicators of their interests to the displayed items, personalized promotion strategies can be formulated to increase their incentives for purchasing future items. Various issues in the application of the adopted localization scheme for locating customers in a store are discussed. To facilitate the item management and space utilization in displaying the items, we propose an enhanced R-tree for indexing the data items maintained in the movement database. Experimental results have demonstrated the effectiveness of the adopted localization scheme in supporting the proposed model.

  17. Articulations of the ribs: a pictorial review.

    Science.gov (United States)

    Sutro, C J; Sutro, W H

    1981-01-01

    The joints of the ribs are true articulations and may be involved by local or general affections of the skeleton. Scoliosis, kyphosis, infections, arthritis (local or general types) may result in fibrosis, abnormal configuration, or ankylosis of the joints in question. In certain types of fractures of the dorsal vertebrae, disruption of the contiguous rib articulations may result in fibrosis or bony depositions and secondarily aid in local stabilization of the fracture. Narrowing of the intercostal spaces, as noted in kyphosis, scoliosis, and arthritis of the dorsal region, does not seem to be routinely associated with clinical findings of intercostal neuralgia.

  18. Nutraceutical Interventions for Promoting Healthy Aging in Invertebrate Models

    Directory of Open Access Journals (Sweden)

    Yuqing Dong

    2012-01-01

    Full Text Available Aging is a complex and inevitable biological process that is associated with numerous chronically debilitating health effects. Development of effective interventions for promoting healthy aging is an active but challenging area of research. Mechanistic studies in various model organisms, noticeably two invertebrates, Caenorhabditis elegans and Drosophila melanogaster, have identified many genes and pathways as well as dietary interventions that modulate lifespan and healthspan. These studies have shed light on some of the mechanisms involved in aging processes and provide valuable guidance for developing efficacious aging interventions. Nutraceuticals made from various plants contain a significant amount of phytochemicals with diverse biological activities. Phytochemicals can modulate many signaling pathways that exert numerous health benefits, such as reducing cancer incidence and inflammation, and promoting healthy aging. In this paper, we outline the current progress in aging intervention studies using nutraceuticals from an evolutionary perspective in invertebrate models.

  19. Natural metrics and least-committed priors for articulated tracking

    DEFF Research Database (Denmark)

    Hauberg, Søren; Sommer, Stefan Horst; Pedersen, Kim Steenstrup

    2012-01-01

    angle space. However, the metric of the joint angle space is rather unintuitive as it ignores both bone lengths and how bones are connected. As Brownian motion is strongly linked with the underlying metric, this has severe impact on the predictive models. We introduce the spatial kinematic manifold...... on the manifold that respects the natural metric. This model is expressed in terms of a stochastic differential equation, which we solve using a novel numerical scheme. Empirically, we validate the new model in a particle filter based articulated tracking system. Here, we not only outperform the standard Brownian...

  20. Applying Transtheoretical Model to Promote Physical Activities Among Women

    OpenAIRE

    2015-01-01

    Background: Physical activity is one of the most important indicators of health in communities but different studies conducted in the provinces of Iran showed that inactivity is prevalent, especially among women. Objectives: Inadequate regular physical activities among women, the importance of education in promoting the physical activities, and lack of studies on the women using transtheoretical model, persuaded us to conduct this study with the aim of determining the application of transtheo...

  1. Nutraceutical Interventions for Promoting Healthy Aging in Invertebrate Models

    OpenAIRE

    2012-01-01

    Aging is a complex and inevitable biological process that is associated with numerous chronically debilitating health effects. Development of effective interventions for promoting healthy aging is an active but challenging area of research. Mechanistic studies in various model organisms, noticeably two invertebrates, Caenorhabditis elegans and Drosophila melanogaster, have identified many genes and pathways as well as dietary interventions that modulate lifespan and healthspan. These studies ...

  2. Promoter recognition based on the maximum entropy hidden Markov model.

    Science.gov (United States)

    Zhao, Xiao-yu; Zhang, Jin; Chen, Yuan-yuan; Li, Qiang; Yang, Tao; Pian, Cong; Zhang, Liang-yun

    2014-08-01

    Since the fast development of genome sequencing has produced large scale data, the current work uses the bioinformatics methods to recognize different gene regions, such as exon, intron and promoter, which play an important role in gene regulations. In this paper, we introduce a new method based on the maximum entropy Markov model (MEMM) to recognize the promoter, which utilizes the biological features of the promoter for the condition. However, it leads to a high false positive rate (FPR). In order to reduce the FPR, we provide another new method based on the maximum entropy hidden Markov model (ME-HMM) without the independence assumption, which could also accommodate the biological features effectively. To demonstrate the precision, the new methods are implemented by R language and the hidden Markov model (HMM) is introduced for comparison. The experimental results show that the new methods may not only overcome the shortcomings of HMM, but also have their own advantages. The results indicate that, MEMM is excellent for identifying the conserved signals, and ME-HMM can demonstrably improve the true positive rate.

  3. Single Word versus Connected Speech Articulation Testing.

    Science.gov (United States)

    Johnson, John P.; And Others

    1980-01-01

    The study compared the productions of 35 articulation impaired children (ages 3 to 10) obtained by picture elicited single word and connected speech sampling methods. Productions were compared on the basis of both the number and type of errors made under the two testing conditions. (Author/PHR)

  4. Articulated Multimedia Physics, Lesson 4, Vectors.

    Science.gov (United States)

    New York Inst. of Tech., Old Westbury.

    As the fourth lesson of the Articulated Multimedia Physics Course, instructional materials are presented in this study guide. The subject matter is concerned with displacements, speeds, scalers, vector sum, and vector analysis.The content is arranged in scrambled form, and the use of matrix transparencies is required for students to control their…

  5. The School and the Articulation of Values.

    Science.gov (United States)

    Lovin, Robin W.

    1988-01-01

    Value neutrality and values clarification fail to foster critical thinking about values. The values articulation approach identifies the rationality that is applied to value claims. It avoids noncognitivism and moral relativism and suggests ways the discussion of values in the classroom prepares students to deal with broader moral issues. (VM)

  6. Computer animation for articulated 3D characters

    NARCIS (Netherlands)

    Kiss, S.

    2002-01-01

    We present a review of the computer animation literature, mainly concentrating on articulated characters and at least some degree of interactivity or real time simulation. Advances in dierent techniques such as key-frame, motion capture (also known as mocap), dynamics, inverse kinematics (IK), contr

  7. Computer Animation for Articulated 3D Characters

    NARCIS (Netherlands)

    Kiss, S.

    2002-01-01

    We present a review of the computer animation literature, mainly concentrating on articulated characters and at least some degree of interactivity or real time simulation. Advances in dierent techniques such as key-frame, motion capture (also known as mocap), dynamics, inverse kinematics (IK),

  8. Single Word versus Connected Speech Articulation Testing.

    Science.gov (United States)

    Johnson, John P.; And Others

    1980-01-01

    The study compared the productions of 35 articulation impaired children (ages 3 to 10) obtained by picture elicited single word and connected speech sampling methods. Productions were compared on the basis of both the number and type of errors made under the two testing conditions. (Author/PHR)

  9. Articulation Research 2004: Summary of Results

    Science.gov (United States)

    Moyle, Jayne

    2005-01-01

    Most junior syndicate teachers have concerns about the speech clarity of some of the children in their class. It is difficult for teachers to know whether to refer such students for speech assessments by their speech-language therapist. This article outlines a project which gathered New Zealand normative data for a test of articulation. A summary…

  10. Activating a Teaching Philosophy in Social Work Education: Articulation, Implementation, and Evaluation

    Science.gov (United States)

    Owens, Larry W.; Miller, J. Jay; Grise-Owens, Erlene

    2014-01-01

    This article describes how to develop a comprehensive teaching philosophy from articulation through implementation to evaluation. Using literature and teaching-learning experiences, we discuss pragmatic steps for using a teaching philosophy to inform, engage, and evaluate teaching-learning. We promote an integrated teaching philosophy to ensure…

  11. Activating a Teaching Philosophy in Social Work Education: Articulation, Implementation, and Evaluation

    Science.gov (United States)

    Owens, Larry W.; Miller, J. Jay; Grise-Owens, Erlene

    2014-01-01

    This article describes how to develop a comprehensive teaching philosophy from articulation through implementation to evaluation. Using literature and teaching-learning experiences, we discuss pragmatic steps for using a teaching philosophy to inform, engage, and evaluate teaching-learning. We promote an integrated teaching philosophy to ensure…

  12. 基于小脑模型神经网络控制的步速跟随智能膝上假肢%Intelligent above-knee prosthesis following healthy leg gait with cerebellar model articulation controller

    Institute of Scientific and Technical Information of China (English)

    喻洪流; 钱省三; 沈凌; 张意斌

    2007-01-01

    目的:研究一种能够跟随健康腿步速控制的新型智能膝上假肢(Intelligent above knee prosthesis,IAKP)的控制机制及其实现方法.方法:首先对国内外IAKP的研究现状及控制机制进行分析,提出了一种新的利用健康腿信号控制假肢步态的方法,设计了基于小脑模型神经网络(Cerebellar model articulation controller,CMAC)控制器的微电脑膝关节系统及相应的实验装置.结果:步态跟随IAKP的控制可通过基于CMAC的PD监督控制实现步速跟随,并配合基于规则的专家控制来识别行走模式.这种控制方法具有动态记忆和快速随动控制能力,可实现假肢对健康腿步速的实时跟踪.结论:基于CMAC控制的IAKP可对健康腿步态进行快速识别与跟踪,为进一步研制健康腿步态跟随控制新型IAKP提供了理论与实验基础.

  13. Characterization of articulated vehicles using ladar seekers

    Science.gov (United States)

    Wellfare, Michael R.; Norris-Zachery, Karen

    1997-08-01

    Many vehicle targets of interest to military automatic target recognition (ATR) possess articulating components: that is, they have components that change position relative to the main body. Many vehicles also have multiple configurations wherein one or more devices or objects may be added to enhance specific military or logistical capabilities. As the expected target set for military ATR becomes more comprehensive, many additional articulations and optional components must be handled. Mobile air defense units often include moving radar antennae as well as turreted guns and missile launchers. Surface-to-surface missile launchers may be encountered with or without missiles, and with the launch rails raised or lowered. Engineers and countermine vehicles have a tremendous number of possible configurations and even conventional battle tanks may very items such as external reactive armor, long- range tanks, turret azimuth, and gun elevation. These changes pose a significant barrier to the target identification process since they greatly increase the range of possible target signatures. When combined with variations already encountered due to target aspect changes, an extremely large number of possible signatures is formed. Conventional algorithms cannot process so many possibilities effectively, so in response, the matching process is often made less selective. This degrades identification performance, increase false alarm rates, and increases data requirements for algorithm testing and training. By explicitly involving articulation in the detection and identification stages of an ATR algorithm, more precise matching constraints can be applied, and better selectivity can be achieve. Additional benefits include the measurement of the position and orientation of articulated components, which often has tactical significance. In this paper, the result of a study investigating the impact of target articulation in ATR for military vehicles are presented. 3D ladar signature

  14. A State Articulated Instructional Objectives Guide for Occupational Education Programs. State Pilot Model for Drafting (Graphic Communications). Part I--Basic. Part II--Specialty Programs. Section A (Mechanical Drafting and Design). Section B (Architectural Drafting and Design).

    Science.gov (United States)

    North Carolina State Dept. of Community Colleges, Raleigh.

    A two-part articulation instructional objective guide for drafting (graphic communications) is provided. Part I contains summary information on seven blocks (courses) of instruction. They are as follow: introduction; basic technical drafting; problem solving in graphics; reproduction processes; freehand drawing and sketching; graphics composition;…

  15. Applying Transtheoretical Model to Promote Physical Activities Among Women

    Science.gov (United States)

    Pirzadeh, Asiyeh; Mostafavi, Firoozeh; Ghofranipour, Fazllolah; Feizi, Awat

    2015-01-01

    Background: Physical activity is one of the most important indicators of health in communities but different studies conducted in the provinces of Iran showed that inactivity is prevalent, especially among women. Objectives: Inadequate regular physical activities among women, the importance of education in promoting the physical activities, and lack of studies on the women using transtheoretical model, persuaded us to conduct this study with the aim of determining the application of transtheoretical model in promoting the physical activities among women of Isfahan. Materials and Methods: This research was a quasi-experimental study which was conducted on 141 women residing in Isfahan, Iran. They were randomly divided into case and control groups. In addition to the demographic information, their physical activities and the constructs of the transtheoretical model (stages of change, processes of change, decisional balance, and self-efficacy) were measured at 3 time points; preintervention, 3 months, and 6 months after intervention. Finally, the obtained data were analyzed through t test and repeated measures ANOVA test using SPSS version 16. Results: The results showed that education based on the transtheoretical model significantly increased physical activities in 2 aspects of intensive physical activities and walking, in the case group over the time. Also, a high percentage of people have shown progress during the stages of change, the mean of the constructs of processes of change, as well as pros and cons. On the whole, a significant difference was observed over the time in the case group (P < 0.01). Conclusions: This study showed that interventions based on the transtheoretical model can promote the physical activity behavior among women. PMID:26834796

  16. Motion estimation of elastic articulated objects from image contours

    Institute of Scientific and Technical Information of China (English)

    PAN Hai-lang; DAI Yue-wei; SHI Lei

    2008-01-01

    A new method of elastic articulated objects (human bodies) modeling was presented based on a new conic curve. The model includes 3D object deform able curves which can represent the deformation of human occluding contours. The deformation of human occluding contour can be represented by adjusting only four de-formation parameters for each limb. Then, the 3D deformation parameters are determined by corresponding 2Dcontours from a sequence of stereo images. The algorithm presented in this paper includes deform able conic curve parameters determination and the plane, 3D conic curve lying on, parameter determination.

  17. Generation of Articulated Mechanisms by Optimization Techniques

    DEFF Research Database (Denmark)

    Kawamoto, Atsushi

    2004-01-01

    that handles topological variations. In this thesis the technique is also extended so as to design the shape as well as the topology of the truss using cross-sectional areas and nodal positions as design variables. This leads to a technique for simultaneous type and dimensional synthesis of articulated...... optimization [Paper 2] 3. Branch and bound global optimization [Paper 3] 4. Path-generation problems [Paper 4] In terms of the objective of the articulated mechanism design problems, the first to third papers deal with maximization of output displacement, while the fourth paper solves prescribed path...... generation problems. From a mathematical programming point of view, the methods proposed in the first and third papers are categorized as deterministic global optimization, while those of the second and fourth papers are categorized as gradient-based local optimization. With respect to design variables, only...

  18. The LPN-ADN articulation project.

    Science.gov (United States)

    Perlich, L J; Hopkin, L A; Kalunian, K; LeGault, G; Fried, M

    1989-01-01

    Faced with a staffing situation where RN positions were needed but there were more LPN positions than were needed. Tucson Medical Center began an LPN-ADN articulation project to rectify the situation without resorting to layoffs. With the cooperation of a local junior college, LPNs are enrolled in ADN programs that provide a more flexible work/study situation. This article describes the program and the results thus far.

  19. Generation of environments: three articulated concepts

    OpenAIRE

    REGO, Nelson

    2010-01-01

    The objective of this article is to expose three concepts, or idea connections, articulators of the concept of generation of environments: the relation environment round/environment among, the establishing interpretation, the dialogal relation of the logisc/dialogal relation of the dialogue. These concepts have been consolidated as idea connections and operational bases for the concept of generation of environments along the course of dialogues with several practices. O objetivo deste arti...

  20. Articulation in Schoolchildren and Adults with Neurofibromatosis Type 1

    Science.gov (United States)

    Cosyns, Marjan; Mortier, Geert; Janssens, Sandra; Bogaert, Famke; D'Hondt, Stephanie; Van Borsel, John

    2012-01-01

    Several authors mentioned the occurrence of articulation problems in the neurofibromatosis type 1 (NF1) population. However, few studies have undertaken a detailed analysis of the articulation skills of NF1 patients, especially in schoolchildren and adults. Therefore, the aim of the present study was to examine in depth the articulation skills of…

  1. Articulated pipes conveying fluid pulsating with high frequency

    DEFF Research Database (Denmark)

    Jensen, Jakob Søndergaard

    1999-01-01

    Stability and nonlinear dynamics of two articulated pipes conveying fluid with a high-frequency pulsating component is investigated. The non-autonomous model equations are converted into autonomous equations by approximating the fast excitation terms with slowly varying terms. The downward hanging...... pipe position will lose stability if the mean flow speed exceeds a certain critical value. Adding a pulsating component to the fluid flow is shown to stabilize the hanging position for high values of the ratio between fluid and pipe-mass, and to marginally destabilize this position for low ratios...

  2. Numerical method for estimation of kinematical parameters for articulated rovers on loose rough terrain

    Institute of Scientific and Technical Information of China (English)

    YU Xin-yi; GAO Hai-bo; DENG Zong-quan

    2009-01-01

    Based on the study of passive articulated rover, a complete suspension kinematics model from wheel to inertial reference frame is presented, which uses D-H method of manipulator and presentation with Euler an-gle of pitch, roll and yaw. An improved contact model is adopted aimed at the loose and rough lunar terrain. U-sing this kinematics model and numerical continuous and discrete Newton' s method with iterative factor, the numerical method for estimation of kinematical parameters of articulated rovers on loose and rough terrain is con-strueted. To demonstrate this numerical method, an example of two torsion bar rocker-bogie lunar rover with eight wheels is presented. Simulation results show that the numerical method for estimation of kinematical pa-rameters of articulated rovers based on improved contact model can improve the precision of kinematical estima-tion on loose and rough terrain and decrease errors caused by contact models established based on general hy-pothesis.

  3. An organisational culture model to promote creativity and innovation

    Directory of Open Access Journals (Sweden)

    Ellen Martins

    2002-10-01

    Full Text Available The aim of the study was to determine what type of organisational culture would support creativity and innovation in an organisation. A new model was developed and compared with the theoretical model. Similarities, differences and new perspectives emerged. The factors trust relationship, working environment, management support and customer orientation on an operational level presented shifts in emphasis in the new model. The trust relationship in particular indicated that trust manifests in openness and sincerity. Trust influences both employee support for change and the probability of successful change, which influence the degree to which creativity and innovation are stimulated and promoted. Opsomming Die doel van die studie was om te bepaal watter tipe organisasiekultuur kreatiwiteit en innovasie in ‘n organisasie sal stimuleer. ‘n Nuwe model is ontwikkel en met die teoretiese model vergelyk. Ooreenkomste, verskille en nuwe perspektiewe het aan die lig gekom. Die faktore vertrouensverhouding, werkomgewing, bestuursondersteuning en kliëntegeoriënteerdheid op ‘n operasionele vlak was klemverskuiwings in die nuwe model. Spesifiek die vertrouensverhouding het daarop gedui dat vertroue manifesteer in openlikheid en opregtheid. Vertroue beïnvloed beide werknemers se steun vir verandering en die waarskynlikheid van suksesvolle verandering, wat die mate waarin kreatiwiteit en innovasie gestimuleer en bevorder word, sal beïnvloed.

  4. An ANN-GA model based promoter prediction in Arabidopsis thaliana using tilling microarray data

    OpenAIRE

    Mishra, Hrishikesh; Singh, Nitya; Misra, Krishna; Lahiri, Tapobrata

    2011-01-01

    Identification of promoter region is an important part of gene annotation. Identification of promoters in eukaryotes is important as promoters modulate various metabolic functions and cellular stress responses. In this work, a novel approach utilizing intensity values of tilling microarray data for a model eukaryotic plant Arabidopsis thaliana, was used to specify promoter region from non-promoter region. A feed-forward back propagation neural network model supported by genetic algorithm was ...

  5. Unicriterion Model: A Qualitative Decision Making Method That Promotes Ethics

    Directory of Open Access Journals (Sweden)

    Fernando Guilherme Silvano Lobo Pimentel

    2011-06-01

    Full Text Available Management decision making methods frequently adopt quantitativemodels of several criteria that bypass the question of whysome criteria are considered more important than others, whichmakes more difficult the task of delivering a transparent viewof preference structure priorities that might promote ethics andlearning and serve as a basis for future decisions. To tackle thisparticular shortcoming of usual methods, an alternative qualitativemethodology of aggregating preferences based on the rankingof criteria is proposed. Such an approach delivers a simpleand transparent model for the solution of each preference conflictfaced during the management decision making process. Themethod proceeds by breaking the decision problem into ‘two criteria– two alternatives’ scenarios, and translating the problem ofchoice between alternatives to a problem of choice between criteriawhenever appropriate. The unicriterion model method is illustratedby its application in a car purchase and a house purchasedecision problem.

  6. Development of a caregiver empowerment model to promote positive outcomes.

    Science.gov (United States)

    Jones, Patricia S; Winslow, Betty W; Lee, Jerry W; Burns, Margaret; Zhang, Xinwei Esther

    2011-02-01

    Family members caring for aging parents experience both negative and positive outcomes from providing care. Theoretical explanations for negative outcomes have been developed. There is need for models that explain and predict positive outcomes. This article describes the evolution of the Caregiver Empowerment Model (CEM) to explain and predict positive outcomes of family caregiving. Although empirical findings support positive outcomes of family caregiving, less attention has been given to theoretical rationale for positive effects. The CEM predicts that, in the presence of filial values and certain background variables, caregiving demands are appraised as challenges instead of stressors. Appraising caregiving demands as a challenge, finding meaning, and using certain types of coping strategies are posited to be associated with growth and well-being. The CEM extends our understanding of the complexity of the caregiving experience, and can serve as a framework to guide in developing and testing theory-based interventions to promote positive outcomes.

  7. Practice of making web multimedia courseware with Articulate Storyline%用 Articulate Storyline制作网络多媒体课件的实践

    Institute of Scientific and Technical Information of China (English)

    李变锋; 王江栓

    2015-01-01

    Web multimedia courseware made with Articulate Storyline that can be run on PC and mobile terminals have such characteristics as rich content , novel design , easy operation and effectively interaction with readers .Therefore, it is an effective complement to the traditional teaching model .%利用Articulate Storyline软件制作可用于PC和移动端运行的网络多媒体课件,具有内容丰富、设计新颖、便于读者操作并能与读者有效互动等特点,是传统教学模式的有效补充。

  8. Modelling the results of health promotion activities in Switzerland: development of the Swiss Model for Outcome Classification in Health Promotion and Prevention.

    Science.gov (United States)

    Spencer, Brenda; Broesskamp-Stone, Ursel; Ruckstuhl, Brigitte; Ackermann, Günter; Spoerri, Adrian; Cloetta, Bernhard

    2008-03-01

    This paper describes the Model for Outcome Classification in Health Promotion and Prevention adopted by Health Promotion Switzerland (SMOC, Swiss Model for Outcome Classification) and the process of its development. The context and method of model development, and the aim and objectives of the model are outlined. Preliminary experience with application of the model in evaluation planning and situation analysis is reported. On the basis of an extensive literature search, the model is situated within the wider international context of similar efforts to meet the challenge of developing tools to assess systematically the activities of health promotion and prevention.

  9. Generalized Poisson-Lindely Distribution in Promotion Time Cure Model

    Directory of Open Access Journals (Sweden)

    Ahmad Reza Baghestani

    2014-12-01

    Full Text Available 1024x768 Long-term survival analysis has been improved in the last decade and most of the models concentrate on the promotion time cure model that proposed by Chen (1999. These models are based on the distribution of latent variable N, number of initiated node cells. In this paper we proposed a Generalized Poisson-Lindely distribution that is another option instead of Negative Binomial distribution when there is overdispersion. The results indicated a better fitness compared to others, because of its more flexibility. Parameter estimation has been done by Bayesian approach, in a real data set and a simulation study has shown the advantages of proposed model. Normal 0 false false false /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman"; mso-ansi-language:#0400; mso-fareast-language:#0400; mso-bidi-language:#0400;}

  10. Dynamics and control of robotic aircraft with articulated wings

    Science.gov (United States)

    Paranjape, Aditya Avinash

    There is a considerable interest in developing robotic aircraft, inspired by birds, for a variety of missions covering reconnaissance and surveillance. Flapping wing aircraft concepts have been put forth in light of the efficiency of flapping flight at small scales. These aircraft are naturally equipped with the ability to rotate their wings about the root, a form of wing articulation. This thesis covers some problems concerning the performance, stability and control of robotic aircraft with articulated wings in gliding flight. Specifically, we are interested in aircraft without a vertical tail, which would then use wing articulation for longitudinal as well as lateral-directional control. Although the dynamics and control of articulated wing aircraft share several common features with conventional fixed wing aircraft, the presence of wing articulation presents several unique benefits as well as limitations from the perspective of performance and control. One of the objective of this thesis is to understand these features using a combination of theoretical and numerical tools. The aircraft concept envisioned in this thesis uses the wing dihedral angles for longitudinal and lateral-directional control. Aircraft with flexible articulated wings are also investigated. We derive a complete nonlinear model of the flight dynamics incorporating dynamic CG location and the changing moment of inertia. We show that symmetric dihedral configuration, along with a conventional horizontal tail, can be used to control flight speed and flight path angle independently of each other. This characteristic is very useful for initiating an efficient perching maneuver. It is shown that wing dihedral angles alone can effectively regulate sideslip during rapid turns and generate a wide range of equilibrium turn rates while maintaining a constant flight speed and regulating sideslip. We compute the turning performance limitations that arise due to the use of wing dihedral for yaw control

  11. Feature classification for tracking articulated surgical tools.

    Science.gov (United States)

    Reiter, Austin; Allen, Peter K; Zhao, Tao

    2012-01-01

    Tool tracking is an accepted capability for computer-aided surgical intervention which has numerous applications, both in robotic and manual minimally-invasive procedures. In this paper, we describe a tracking system which learns visual feature descriptors as class-specific landmarks on an articulated tool. The features are localized in 3D using stereo vision and are fused with the robot kinematics to track all of the joints of the dexterous manipulator. Experiments are performed using previously-collected porcine data from a surgical robot.

  12. The velic traverse: an independent oral articulator?

    Science.gov (United States)

    Gick, Bryan; Francis, Naomi; Klenin, Anna; Mizrahi, Ezra; Tom, Denise

    2013-03-01

    Two speech functions have traditionally been ascribed to the velum: opening and closing the velopharyngeal port and providing a passive surface against which the tongue can produce oral constrictions. Contrary to this passive oral function, the present x-ray study finds that a substantial portion of the velum moves to constrict the oropharyngeal isthmus for French uvular /ʁ/. This substructure, designated the velic traverse, functions independently of the parts of the velum used for velopharyngeal port closure, thus acting as an oral articulator. An active velic traverse challenges methods for estimating vocal tract shapes based on tongue posture alone.

  13. Serpentine Locomotion Articulated Chain: ANA II

    Directory of Open Access Journals (Sweden)

    A. M. Cardona

    2005-01-01

    Full Text Available When humanity faces challenges in solving problems beyond their technical resources, and has no foundation to solve a problem, engineering must search for an answer developing new concepts and innovative frameworks to excel these limitations and travel beyond our capabilities. This project “Serpentine locomotion articulated chain: ANA II” is a self-contained robot built to evaluate the behavior of the platform being capable of serpentine movements, in a modular chain mechanical design, based on a master/slave architecture.

  14. Topic-Focus Articulation of Isotopy

    Directory of Open Access Journals (Sweden)

    Radim Sova

    2012-09-01

    Full Text Available The paper deals with linguistic phenomena at suprasentential level. In particular, it looks into how textual analysis can be enhanced by supplementing the Parisian programme of interpretive semantics, as devised by François Rastier, namely his theory of isotopies, with elementary aspects of topic-focus articulation (TFA, as well as contextual boundness (CB and contextual non-boundness (CN, as elaborated within the Praguian linguistic tradition (V. Mathesius, P. Sgall, E. Hajičová, F. Daneš, J. Firbas, and how the descriptive power of the former can be increased by the latter. In this respect, it is argued that two types of TFA phenomena interact during any process of textual interpretation: those of topic-focus articulation at the level of sentence, conceiving lexical morphs as thematic (T and/or rhematic (R, as well as contextually bound (CB and/or contextually non-bound (CN, and those of topic-focus articulation at the level of isotopy, with each isotopy being conceived as structured around a center (an abstract semantic unit and periphery (a span of concrete utterances. Two types of such interaction are described, each defined by either correlation, or non-correlation of the CB and CN semes at the levels of isotopy and sentence, respectively: thematic-rhematic isotopy, induced by co-occurrence of the CB seme of the center and the CB seme of the periphery; and thematic-rhematic allotopy (i.e. non-isotopy, induced by co-occurrence of the CB seme of the center and the CN seme of the periphery. Since topic-focus isotopies and allotopies can be perceived as members of privative oppositions, a tentative system of such oppositions is presented, based on linguistic analyses of selected European Commission texts drafted in English and their Czech translations. The author’s ultimate intention is to show that the semantic features of topic-focus articulation at the sentential and suprasentential levels are both structurally parallel and

  15. Easy cross parameterization for articulated shapes

    Institute of Scientific and Technical Information of China (English)

    Jian-wei HU; Li-gang LIU; Guo-zhao WANG

    2009-01-01

    This paper presents a novel interactive system for establishing compatible meshes for articulated shapes. Given two mesh surfaces, our system automatically generates both the global level component correspondence and the local level feature correspondence. Users can use some sketch-based tools to specify the correspondence in an intuitive and easy way. Then all the other vertex correspondences could be generated automatically. The cross parameterization preserves both high level and low level features of the shapes. The technique showed in the system benefits various applications in graphics including mesh inter-polation, deformation transfer, and texture transfer.

  16. Vibration acceleration promotes bone formation in rodent models

    Science.gov (United States)

    Uchida, Ryohei; Nakata, Ken; Kawano, Fuminori; Yonetani, Yasukazu; Ogasawara, Issei; Nakai, Naoya; Mae, Tatsuo; Matsuo, Tomohiko; Tachibana, Yuta; Yokoi, Hiroyuki; Yoshikawa, Hideki

    2017-01-01

    centrifuge acceleration group had no significant difference compared those in control-CA group. Union rate and BV in the low-magnitude group of RFH model were also significantly higher than those in the other groups (Union rate: 60% v.s. 0% in the high-magnitude group and 10% in the control-VA group, BV: 0.69±0.30mm3 v.s. 0.15±0.09mm3 in high-magnitude group and 0.22±0.17mm3 in control-VA group). BV/TV in the low-magnitude group of RFH model was significantly higher than that in control-VA group (59.4±14.9% v.s. 35.8±13.5%). On the other hand, radiographic union rate (10% in centrifuge acceleration group v.s. 20% in control-CA group) and micro-CT parameters in RFH model were not significantly different between two groups in the constant acceleration studies. Radiographic images of non-union rib fractures showed cartilage at the fracture site and poor new bone formation, whereas union samples showed only new bone. In conclusion, low-magnitude vibration acceleration promoted bone formation at the trunk in both BMP-induced ectopic bone formation and rib fracture healing models. However, the micro-CT parameters were not similar between two models, which suggested that there might be difference in the mechanism of effect by vibration between two models. PMID:28264058

  17. Articulation rate across dialect, age, and gender.

    Science.gov (United States)

    Jacewicz, Ewa; Fox, Robert A; O'Neill, Caitlin; Salmons, Joseph

    2009-07-01

    The understanding of sociolinguistic variation is growing rapidly, but basic gaps still remain. Whether some languages or dialects are spoken faster or slower than others constitutes such a gap. Speech tempo is interconnected with social, physical and psychological markings of speech. This study examines regional variation in articulation rate and its manifestations across speaker age, gender and speaking situations (reading vs. free conversation). The results of an experimental investigation show that articulation rate differs significantly between two regional varieties of American English examined here. A group of Northern speakers (from Wisconsin) spoke significantly faster than a group of Southern speakers (from North Carolina). With regard to age and gender, young adults read faster than older adults in both regions; in free speech, only Northern young adults spoke faster than older adults. Effects of gender were smaller and less consistent; men generally spoke slightly faster than women. As the body of work on the sociophonetics of American English continues to grow in scope and depth, we argue that it is important to include fundamental phonetic information as part of our catalog of regional differences and patterns of change in American English.

  18. An Articulated Inspection Arm for fusion purposes

    Energy Technology Data Exchange (ETDEWEB)

    Villedieu, E., E-mail: eric.villedieu@cea.fr [CEA-IRFM, 13108 Saint Paul lez Durance (France); Bruno, V.; Pastor, P.; Gargiulo, L. [CEA-IRFM, 13108 Saint Paul lez Durance (France); Song, Y.T.; Cheng, Y.; Feng, H. [Institute of Plasma Physics, Chinese Academy of Sciences, Hefei (China); Liu, C. [CEA-IRFM, 13108 Saint Paul lez Durance (France); Institute of Plasma Physics, Chinese Academy of Sciences, Hefei (China); Shi, S.S. [Institute of Plasma Physics, Chinese Academy of Sciences, Hefei (China)

    2016-11-01

    Highlights: • Requirements for in vacuum tokamak inspection are presented. • Development of a prototype of the Articulated Inspection Arm is described. • The upgrade of the prototype to convert it into a fully operational device is detailed. • Future applications of inspection robots in the new fusion reactors is discussed. - Abstract: Fusion Tokamaks are complex machines which require special conditions for their operation, in particular, high vacuum inside the vessel and high temperature of the vessel walls. During plasma phases, the first wall components are highly stressed and a control is necessary in case of doubt about their condition. To be able to make safely such an inspection in a short period of time is a great advantage. The Articulated Inspection Arm (AIA) developed by the CEA provides the capability for fast inspections of the first wall overall surface keeping the vacuum and temperature conditions of the vessel. The robot prototype was validated in Tore Supra in 2008. In the frame of a joint laboratory, CEA/IRFM and ASIPP have decided to upgrade the existing AIA prototype to use it routinely in the EAST and WEST tokamaks. The robot has followed an important upgrade program in 2013 and 2014. The document presents the various upgrades made on the mechanics, the sensors, the electronics, the control station and the integration adaptation for the operation on EAST. From the AIA experience, thoughts for future inspection robots are given.

  19. Nonlinearity between acoustics and articulation in Hungarian transparent vowels

    Science.gov (United States)

    Benus, Stefan; Kirke, Karen D.; Gafos, Adamantios I.

    2001-05-01

    We present novel results from the acoustic and articulatory investigation of the production of the transparent vowels (TVs) /i/, /i:/, /e:/ in Hungarian (colon denotes length). The acoustic measurements of the front-back distinction (second formant, the difference of the first and second formants [Ladefoged, 1993]) show that the effect of adjacent back vowels on the front quality of the TVs is only weakly significant. The articulatory measurements of the same data, however, show that adjacent back vowels cause highly significant retraction of the tongue body during the production of the front TVs. The significance of this finding lies in its relevance to the relationship between phonetics and phonology. Our results demonstrate that minor phonetic differences in articulation, impossible to access by traditional theory, correlate with full-fledged phonological alternation of suffix selection in Hungarian. Traditional phonological accounts predict no effect of continuous phonetic details on discrete phonological generalizations. This is supported in our acoustic data but contrasts with our articulatory findings. In the paper we propose a dynamic model where phonological transparency is directly related to nonlinearity between acoustics and articulation [Stevens, 1989; Wood, 1979]. [Work supported by NIH.

  20. Nonlinearity between acoustics and articulation in Hungarian transparent vowels

    Science.gov (United States)

    Benus, Stefan; Kirke, Karen D.; Gafos, Adamantios I.

    2004-05-01

    We present novel results from the acoustic and articulatory investigation of the production of the transparent vowels (TVs) /i/, /i:/, /e:/ in Hungarian (colon denotes length). The acoustic measurements of the front-back distinction (second formant, the difference of the first and second formants [Ladefoged, 1993]) show that the effect of adjacent back vowels on the front quality of the TVs is only weakly significant. The articulatory measurements of the same data, however, show that adjacent back vowels cause highly significant retraction of the tongue body during the production of the front TVs. The significance of this finding lies in its relevance to the relationship between phonetics and phonology. Our results demonstrate that minor phonetic differences in articulation, impossible to access by traditional theory, correlate with full-fledged phonological alternation of suffix selection in Hungarian. Traditional phonological accounts predict no effect of continuous phonetic details on discrete phonological generalizations. This is supported in our acoustic data but contrasts with our articulatory findings. In the paper we propose a dynamic model where phonological transparency is directly related to nonlinearity between acoustics and articulation [Stevens, 1989; Wood, 1979]. [Work supported by NIH.

  1. The technology of mobile robot with articulated crawler mechanism

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Seung Ho; Kim, Byung Soo; Kim, Chang Hoi; Hwang, Suk Yong; Suh, Yong Chil; Lee, Yung Kwang; Sin, Jae Ho [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    1995-01-01

    The main application of a mobile robot are to do the inspection and maintenance tasks in the primary and auxiliary building, and to meet with the radiological emergency response in nuclear power plant. Our project to develop crawler-type mobile robot has been divided into 3 phases. In 1 st phase, the-state-of-the-arts of mobile robot technology were studied and analyzed. And then the technical report `development of mobile robot technology for the light work` was published on July, 1993. In current phase, the articulated crawler type mobile robot named as ANDROS Mark VI was purchased to evaluate deeply its mechanism and control system. Then we designed the autonomous track surface, to get the inclination angle of robot, and to control the front and rear auxiliary track autonomously during climbing up and down stairs. And also, the autonomous stair-climbing algorithm has been developed to going over stairs with high stability. For the final phase, the advanced model of articulated crawler type mobile robot is going to be developed. (Author) 13 refs., 30 figs., 12 tabs.

  2. Multivariable Linear Regression Model for Promotional Forecasting:The Coca Cola - Morrisons Case

    OpenAIRE

    Zheng, Yiwei/Y

    2009-01-01

    This paper describes a promotional forecasting model, built by linear regression module in Microsoft Excel. It intends to provide quick and reliable forecasts with a moderate credit and to assist the CPFR between the Coca Cola Enterprises (CCE) and the Morrisons. The model is derived from previous researches and literature review on CPFR, promotion, forecasting and modelling. It is designed as a multivariable linear regression model, which involves several promotional mix as variables includi...

  3. Scan-based volume animation driven by locally adaptive articulated registrations.

    Science.gov (United States)

    Rhee, Taehyun; Lewis, J P; Neumann, Ulrich; Nayak, Krishna S

    2011-03-01

    This paper describes a complete system to create anatomically accurate example-based volume deformation and animation of articulated body regions, starting from multiple in vivo volume scans of a specific individual. In order to solve the correspondence problem across volume scans, a template volume is registered to each sample. The wide range of pose variations is first approximated by volume blend deformation (VBD), providing proper initialization of the articulated subject in different poses. A novel registration method is presented to efficiently reduce the computation cost while avoiding strong local minima inherent in complex articulated body volume registration. The algorithm highly constrains the degrees of freedom and search space involved in the nonlinear optimization, using hierarchical volume structures and locally constrained deformation based on the biharmonic clamped spline. Our registration step establishes a correspondence across scans, allowing a data-driven deformation approach in the volume domain. The results provide an occlusion-free person-specific 3D human body model, asymptotically accurate inner tissue deformations, and realistic volume animation of articulated movements driven by standard joint control estimated from the actual skeleton. Our approach also addresses the practical issues arising in using scans from living subjects. The robustness of our algorithms is tested by their applications on the hand, probably the most complex articulated region in the body, and the knee, a frequent subject area for medical imaging due to injuries.

  4. OPTIMAL TRAINING POLICY FOR PROMOTION - STOCHASTIC MODELS OF MANPOWER SYSTEMS

    Directory of Open Access Journals (Sweden)

    V.S.S. Yadavalli

    2012-01-01

    Full Text Available In this paper, the optimal planning of manpower training programmes in a manpower system with two grades is discussed. The planning of manpower training within a given organization involves a trade-off between training costs and expected return. These planning problems are examined through models that reflect the random nature of manpower movement in two grades. To be specific, the system consists of two grades, grade 1 and grade 2. Any number of persons in grade 2 can be sent for training and after the completion of training, they will stay in grade 2 and will be given promotion as and when vacancies arise in grade 1. Vacancies arise in grade 1 only by wastage. A person in grade 1 can leave the system with probability p. Vacancies are filled with persons in grade 2 who have completed the training. It is assumed that there is a perfect passing rate and that the sizes of both grades are fixed. Assuming that the planning horizon is finite and is T, the underlying stochastic process is identified as a finite state Markov chain and using dynamic programming, a policy is evolved to determine how many persons should be sent for training at any time k so as to minimize the total expected cost for the entire planning period T.

  5. The role of virtual articulator in prosthetic and restorative dentistry.

    Science.gov (United States)

    Koralakunte, Pavankumar Ravi; Aljanakh, Mohammad

    2014-07-01

    Virtual reality is a computer based technology linked with the future of dentistry and dental practice. The virtual articulator is one such application in prosthetic and restorative dentistry based on virtual reality that will significantly reduce the limitations of the mechanical articulator, and by simulation of real patient data, allow analyses with regard to static and dynamic occlusion as well as to jaw relation. It is the purpose of this article to present the concepts and strategies for a future replacement of the mechanical articulator by a virtual one. Also, a brief note on virtual reality haptic system has been highlighted along with newly developed touch enabled virtual articulator.

  6. Consumer choice models on the effect of promotions in retailing

    NARCIS (Netherlands)

    Guyt, Jonne

    2015-01-01

    This doctoral thesis contains three empirical essays regarding the effect of promotions on consumer choices in a retailing context. The first essay studies the scheduling of featured price cuts for national brands, across retail chains. It shows that coordinating promotions across chains influences

  7. Disruptions in Women's Self-Promotion: The Backlash Avoidance Model

    Science.gov (United States)

    Moss-Racusin, Corinne A.; Rudman, Laurie A.

    2010-01-01

    Women experience social and economic penalties (i.e., backlash) for self-promotion, a behavior that violates female gender stereotypes yet is necessary for professional success. However, it is unknown whether and how the threat of backlash interferes with women's ability to self-promote. The present research examined the effects of fear of…

  8. Framework for articulating instructional practices and conceptions

    Directory of Open Access Journals (Sweden)

    Melissa Dancy

    2007-05-01

    Full Text Available We present and describe the development of a framework for assessing or categorizing instructional practices and related conceptions in the context of introductory physics instruction. The purpose of the framework is for articulating practices and conceptions of individual instructors or of curricula. It was developed based on the research literature and interviews with physics faculty and contains ideas with widespread acceptance as well as some outside mainstream rhetoric. We provide an example of how this framework can be applied by using it to categorize aspects of three well-known research-based curricula. The results of this categorization highlight areas that are common in research-based curricular designs and other areas that are less embraced but worthy of consideration.

  9. Landing Motion Control of Articulated Hopping Robot

    Directory of Open Access Journals (Sweden)

    Youngil Youm

    2008-11-01

    Full Text Available This paper deals with the landing motion of an articulated legged robot. Humans use a peculiar crouching motion to land safely which can be characterized by body stiffness and damping. A stiffness controller formulation is used to realize this human behavior for the robot. Using this method, the landing motion is achieved with only the desired body stiffness and damping values, without desired COG(Center of Gravity or joint paths. To achieve soft landing, variable body stiffness and damping values were optimized. PBOT, which has four links with flexible joints was used for validation of the landing controller. A body stiffness and damping controller was used as an outer landing control loop and a fast subsystem controller for flexible joints was used as an inner force control loop. Simulations and experimental results about the landing motion are presented to show the performance of the body stiffness and damping controller.

  10. Kinematical Analysis of an Articulated Mechanism

    CERN Document Server

    Fleischfresser, Luciano

    2015-01-01

    The purpose of this work is twofold: to present mathematical expressions for the kinematics of an articulated mechanism and to perform numerical experiments with the implemented Fortran code. The system of rigid parts is made of two slender bars and a disk. A constant 2 rad/s counterclockwise rotation rate is imposed on the disk triggering the planar motion of the longer bar (link) and the rotation of the shorter one (output). Angular relations, velocities and accelerations are analyzed for a 90-degree turn of the disk. The inversion of the linking bar sense of rotation is well captured by the simulation, and the paper and pencil solutions that may lead to wrong conclusions are explained. Equations are derived from first principles and the Fortran code is placed under version control (currently, v.0.8-beta). This computer project is relevant for those in charge of vector dynamics courses and wishing to expose students to project-based learning activities.

  11. A Novel Relative Navigation Control Strategy Based on Relation Space Method for Autonomous Underground Articulated Vehicles

    Directory of Open Access Journals (Sweden)

    Fengqian Dou

    2016-01-01

    Full Text Available This paper proposes a novel relative navigation control strategy based on the relation space method (RSM for articulated underground trackless vehicles. In the RSM, a self-organizing, competitive neural network is used to identify the space around the vehicle, and the spatial geometric relationships of the identified space are used to determine the vehicle’s optimal driving direction. For driving control, the trajectories of the articulated vehicles are analyzed, and data-based steering and speed control modules are developed to reduce modeling complexity. Simulation shows that the proposed RSM can choose the correct directions for articulated vehicles in different tunnels. The effectiveness and feasibility of the resulting novel relative navigation control strategy are validated through experiments.

  12. Fuzzy Reliability Design for the Interference Articulation of a Roller Shaft

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    With regard to function, the strengths for interference articulation of a roller shaft formed a series system. As the three strength reliabilities conditioned each other, there was a problem for the system reliability to apportion rationally. In fact, there was a transition from safety to deactivation. The state of structure was fuzziness which was in both safety and non-safety states. Therefore the reliability was a fuzzy event which considered the randomness for some design parameters and the fuzziness for the thresholds between generalized strength safety and deactivation. The mathematical model of fuzzy reliability design for the interference articulation of the roller shaft was presented. Eight design examples were calculated. ``

  13. Estudo da técnica da sindesmoplastia extra-articular com fascia lata autógena: modelo em cães Study of the extra articulate syndesmoplasty technique with autogenous fascia lata: a model in dogs

    Directory of Open Access Journals (Sweden)

    Manoel Luiz Ferreira

    2009-04-01

    Full Text Available OBJETIVO: Avaliar a eficácia da técnica extra-capsular para o tratamento de ruptura do ligamento cruzado anterior em cães. MÉTODOS: Foi realizada a reparação cirúrgica extra-articular, sem artrotomia do ligamento cruzado anterior, com a utilização da fáscia lata autógena para estabilização da articulação do joelho em seis animais que apresentaram claudicação grave e movimento de gaveta positivo. RESULTADOS: A técnica cirúrgica extra-articular foi eficaz com boa estabilização articular e evolução satisfatória. CONCLUSÃO: A via extra capsular com uso da fáscia lata para correção da ruptura do ligamento cruzado anterior mostrou-se útil haja vista tratar-se de um procedimento simples e de rápida execução, causando o mínimo dano tecidual e recuperação pós-operatória eficiente.OBJETIVE: To evaluate extra-capsular technique for the treatment of the anterior cruciate ligament rupture, in dogs. METHODS: It was performed an extra-articulate surgery without arthrotomy of the anterior cruciate ligament by using a strip of the autogenous fascia lata for stabilization of the knee joint in six animals which had severe claudication and drawer movement sign positive. RESULTS: The extra articulate technique was effective with good knee stabilization and satisfactory outcome. CONCLUSION: The use of the fascia lata with an extra capsular technique to fix the rupture of the anterior cruciate ligament seems to be useful once it is a simple and rapid procedure with minimum tissue damage and efficient postoperative recovery.

  14. [Articulation between child and adolescent mental health services].

    Science.gov (United States)

    Delfini, Patricia Santos de Souza; Reis, Alberto Olavo Advincula

    2012-02-01

    The objective of this paper was to describe and analyze the articulation between children and adolescent mental health care interventions undertaken by teams working under the Family Health Strategy (FHS) and Psychosocial Care Centers for Children and Adolescents (CAPSI). In order to achieve these objectives, semi-structured interviews were conducted with five CAPSI and 13 FHS managers from five different regions of the city of São Paulo, Brazil. The 18 interviews were transcribed and analyzed froma hermeneutic perspective. It was found that interactions between the FHS and CAPSI occur mainly through referral of cases, matrix support or partnerships in cases concerning CAPSI. Obstacles, such as a lack of human resources, productivity goals and lack of training in mental health of FHS professionals were mentioned. The referral system and passing responsibility for mental health cases to specialized services and the hegemonic biomedical model and the fragmentation of care are common place in these services.

  15. Informal work and formal plans: Articulating the active role of patients in cancer trajectories

    DEFF Research Database (Denmark)

    Dalsted, R.; Hølge-Hazelton, Bibi; Kousgaard, MB;

    2013-01-01

    Formal pathways models outline that patients should receive information in order to experience a coherent journey but do not describe an active role for patients or their relatives. The aim of this is paper is to articulate and discuss the active role of patients during their cancer trajectories...

  16. Informal work and formal plans: Articulating the active role of patients in cancer trajectories

    DEFF Research Database (Denmark)

    Dalsted, R.; Hølge-Hazelton, Bibi; Kousgaard, MB

    2013-01-01

    Formal pathways models outline that patients should receive information in order to experience a coherent journey but do not describe an active role for patients or their relatives. The aim of this is paper is to articulate and discuss the active role of patients during their cancer trajectories...

  17. Using articulation and inscription as catalysts for reflection: Design principles for reflective inquiry

    Science.gov (United States)

    Loh, Ben Tun-Bin

    2003-07-01

    The demand for students to engage in complex student-driven and information-rich inquiry investigations poses challenges to existing learning environments. Students are not familiar with this style of work, and lack the skills, tools, and expectations it demands, often forging blindly forward in the investigation. If students are to be successful, they need to learn to be reflective inquirers, periodically stepping back from an investigation to evaluate their work. The fundamental goal of my dissertation is to understand how to design learning environments to promote and support reflective inquiry. I have three basic research questions: how to define this mode of work, how to help students learn it, and understanding how it facilitates reflection when enacted in a classroom. I take an exploratory approach in which, through iterative cycles of design, development, and reflection, I develop principles of design for reflective inquiry, instantiate those principles in the design of a software environment, and test that software in the context of classroom work. My work contributes to the understanding of reflective inquiry in three ways: First, I define a task model that describes the kinds of operations (cognitive tasks) that students should engage in as reflective inquirers. These operations are defined in terms of two basic tasks: articulation and inscription, which serve as catalysts for externalizing student thinking as objects of and triggers for reflection. Second, I instantiate the task model in the design of software tools (the Progress Portfolio). And, through proof of concept pilot studies, I examine how the task model and tools helped students with their investigative classroom work. Finally, I take a step back from these implementations and articulate general design principles for reflective inquiry with the goal of informing the design of other reflective inquiry learning environments. There are three design principles: (1) Provide a designated work space

  18. The Oklahoma PN/ADN Articulation Project Report.

    Science.gov (United States)

    Oklahoma State Regents for Higher Education, Oklahoma City.

    In response to a critical nursing shortage in the state of Oklahoma, the Oklahoma Practical Nursing (PN)/Associate Degree Nursing (ADN) Articulation Project Coordinating Committee was formed in spring 1990 to develop a proposal for program articulation. A curriculum matrix was designed and adopted for use by five regional subcommittees which…

  19. Design and wear testing of a temporomandibular joint prosthesis articulation

    NARCIS (Netherlands)

    van Loon, JP; Verkerke, GJ; de Vries, MP; de Bont, LGM

    2000-01-01

    As part of the development of a total temporomandibular joint prosthesis, a prosthesis articulation was designed. The articulation consists of a spherical head (ball) of the mandibular part, rotating against an enveloping ultra-high-molecular-weight polyethylene (UHMWPE) disc with a flat cranial sid

  20. Design and wear testing of a temporomandibular joint prosthesis articulation

    NARCIS (Netherlands)

    van Loon, JP; Verkerke, GJ; de Vries, MP; de Bont, LGM

    As part of the development of a total temporomandibular joint prosthesis, a prosthesis articulation was designed. The articulation consists of a spherical head (ball) of the mandibular part, rotating against an enveloping ultra-high-molecular-weight polyethylene (UHMWPE) disc with a flat cranial

  1. The use of articulators in UK dental schools.

    Science.gov (United States)

    Hindle, J R; Craddock, H L

    2006-11-01

    The increasing complexity of many restorative procedures often involves articulation of study and working casts to ensure accurate fabrication of restorations. Correct selection and use of articulators can be crucial to successful restoration. The aim of this paper is to determine which articulators are recommended for various restorative procedures in UK dental schools, for use by undergraduate students. A questionnaire-based study of all UK dental schools was carried out, with a 100% response rate. Recommended articulator application for specified procedures was established from the literature and questionnaire results were compared with this. The results indicated that dental schools in the UK generally teach appropriate articulator use for most procedures. However, there are some limited areas of what may be argued to be inappropriate recommendation in some establishments.

  2. Parkinson Disease Detection from Speech Articulation Neuromechanics

    Directory of Open Access Journals (Sweden)

    Pedro Gómez-Vilda

    2017-08-01

    Full Text Available Aim: The research described is intended to give a description of articulation dynamics as a correlate of the kinematic behavior of the jaw-tongue biomechanical system, encoded as a probability distribution of an absolute joint velocity. This distribution may be used in detecting and grading speech from patients affected by neurodegenerative illnesses, as Parkinson Disease.Hypothesis: The work hypothesis is that the probability density function of the absolute joint velocity includes information on the stability of phonation when applied to sustained vowels, as well as on fluency if applied to connected speech.Methods: A dataset of sustained vowels recorded from Parkinson Disease patients is contrasted with similar recordings from normative subjects. The probability distribution of the absolute kinematic velocity of the jaw-tongue system is extracted from each utterance. A Random Least Squares Feed-Forward Network (RLSFN has been used as a binary classifier working on the pathological and normative datasets in a leave-one-out strategy. Monte Carlo simulations have been conducted to estimate the influence of the stochastic nature of the classifier. Two datasets for each gender were tested (males and females including 26 normative and 53 pathological subjects in the male set, and 25 normative and 38 pathological in the female set.Results: Male and female data subsets were tested in single runs, yielding equal error rates under 0.6% (Accuracy over 99.4%. Due to the stochastic nature of each experiment, Monte Carlo runs were conducted to test the reliability of the methodology. The average detection results after 200 Montecarlo runs of a 200 hyperplane hidden layer RLSFN are given in terms of Sensitivity (males: 0.9946, females: 0.9942, Specificity (males: 0.9944, females: 0.9941 and Accuracy (males: 0.9945, females: 0.9942. The area under the ROC curve is 0.9947 (males and 0.9945 (females. The equal error rate is 0.0054 (males and 0.0057 (females

  3. An improved model for the hTERT promoter quadruplex.

    Directory of Open Access Journals (Sweden)

    Jonathan B Chaires

    Full Text Available Mutations occur at four specific sites in the hTERT promoter in >75% of glioblastomas and melanomas, but the mechanism by which the mutations affect gene expression remains unexplained. We report biophysical computational studies that show that the hTERT promoter sequence forms a novel G-quadruplex structure consisting of three contiguous, stacked parallel quadruplexes. The reported hTERT mutations map to the central quadruplex within this structure, and lead to an alteration of its hydrodynamic properties and stability.

  4. BIOENERGETIC DIFFERENCES DURING WALKING AND RUNNING IN TRANSFEMORAL AMPUTEE RUNNERS USING ARTICULATING AND NON-ARTICULATING KNEE PROSTHESES

    Science.gov (United States)

    Highsmith, M. Jason; Kahle, Jason T.; Miro, Rebecca M.; Mengelkoch, Larry J.

    2016-01-01

    Transfemoral amputation (TFA) patients require considerably more energy to walk and run than non-amputees. The purpose of this study was to examine potential bioenergetic differences (oxygen uptake (VO2), heart rate (HR), and ratings of perceived exertion (RPE)) for TFA patients utilizing a conventional running prosthesis with an articulating knee mechanism versus a running prosthesis with a non-articulating knee joint. Four trained TFA runners (n = 4) were accommodated to and tested with both conditions. VO2 and HR were significantly lower (p ≤ 0.05) in five of eight fixed walking and running speeds for the prosthesis with an articulating knee mechanism. TFA demonstrated a trend for lower RPE at six of eight walking speeds using the prosthesis with the articulated knee condition. A trend was observed for self-selected walking speed, self-selected running speed, and maximal speed to be faster for TFA subjects using the prosthesis with the articulated knee condition. Finally, all four TFA participants subjectively preferred running with the prosthesis with the articulated knee condition. These findings suggest that, for trained TFA runners, a running prosthesis with an articulating knee prosthesis reduces ambulatory energy costs and enhances subjective perceptive measures compared to using a non-articulating knee prosthesis. PMID:28066524

  5. Optimal visual-haptic integration with articulated tools.

    Science.gov (United States)

    Takahashi, Chie; Watt, Simon J

    2017-05-01

    When we feel and see an object, the nervous system integrates visual and haptic information optimally, exploiting the redundancy in multiple signals to estimate properties more precisely than is possible from either signal alone. We examined whether optimal integration is similarly achieved when using articulated tools. Such tools (tongs, pliers, etc) are a defining characteristic of human hand function, but complicate the classical sensory 'correspondence problem' underlying multisensory integration. Optimal integration requires establishing the relationship between signals acquired by different sensors (hand and eye) and, therefore, in fundamentally unrelated units. The system must also determine when signals refer to the same property of the world-seeing and feeling the same thing-and only integrate those that do. This could be achieved by comparing the pattern of current visual and haptic input to known statistics of their normal relationship. Articulated tools disrupt this relationship, however, by altering the geometrical relationship between object properties and hand posture (the haptic signal). We examined whether different tool configurations are taken into account in visual-haptic integration. We indexed integration by measuring the precision of size estimates, and compared our results to optimal predictions from a maximum-likelihood integrator. Integration was near optimal, independent of tool configuration/hand posture, provided that visual and haptic signals referred to the same object in the world. Thus, sensory correspondence was determined correctly (trial-by-trial), taking tool configuration into account. This reveals highly flexible multisensory integration underlying tool use, consistent with the brain constructing internal models of tools' properties.

  6. Vocal tract articulation in zebra finches.

    Directory of Open Access Journals (Sweden)

    Verena R Ohms

    Full Text Available BACKGROUND: Birdsong and human vocal communication are both complex behaviours which show striking similarities mainly thought to be present in the area of development and learning. Recent studies, however, suggest that there are also parallels in vocal production mechanisms. While it has been long thought that vocal tract filtering, as it occurs in human speech, only plays a minor role in birdsong there is an increasing number of studies indicating the presence of sound filtering mechanisms in bird vocalizations as well. METHODOLOGY/PRINCIPAL FINDINGS: Correlating high-speed X-ray cinematographic imaging of singing zebra finches (Taeniopygia guttata to song structures we identified beak gape and the expansion of the oropharyngeal-esophageal cavity (OEC as potential articulators. We subsequently manipulated both structures in an experiment in which we played sound through the vocal tract of dead birds. Comparing acoustic input with acoustic output showed that OEC expansion causes an energy shift towards lower frequencies and an amplitude increase whereas a wide beak gape emphasizes frequencies around 5 kilohertz and above. CONCLUSION: These findings confirm that birds can modulate their song by using vocal tract filtering and demonstrate how OEC and beak gape contribute to this modulation.

  7. Nasal reconstruction with articulated irradiated rib cartilage

    Energy Technology Data Exchange (ETDEWEB)

    Murakami, C.S.; Cook, T.A.; Guida, R.A. (Univ. of Washington School of Medicine, Seattle (USA))

    1991-03-01

    Nasal structural reconstruction is a formidable task in cases where there is loss of support to both the nasal dorsum and tip. A multitude of surgical approaches and materials have been used for the correction of the saddle-nose deformity with varying degrees of success. Articulated irradiated rib cartilage inserted through an external rhinoplasty approach was used to reconstruct nasal deformities in 18 patients over a 6-year period. Simultaneous use of a midline forehead flap to reconstruct the overlying soft tissue was required in four cases. Follow-up ranged from 1 to 6 years (mean, 2.8 years). Results were rewarding in most cases with marked improvement in nasal support and airway. Revision and/or replacement secondary to trauma or warping of the graft was required in four cases. None of the patients exhibited infection, extrusion, or noticeable resorption. A description of the surgical technique, review of all the cases, and recommendation for continued use of this graft material are discussed.

  8. [Educational theories and models in health-promoting interventions: a critical analysis].

    Science.gov (United States)

    Raffaele, Barbara; Matarese, Maria; Alvaro, Rosaria; Piredda, Michela; De Marinis, Maria Grazia

    2016-01-01

    Health promotion interventions are aimed at improving health by seeking to influence lifestyles, healthcare services and physical, cultural and socioeconomic environments. Several publications support the relevance of theory-based interventions directed to promoting health. However, the adoption of an educational conceptual framework in the planning and evaluation of health promotion interventions is still limited. The aim of this article is to describe the educational paradigms for health promotion intervention and analyse the main educational theories and models used in literature, reporting the international debate about the type and level of application of different theoretical frameworks in health promotion interventions.

  9. ARTICULATION DISORDERS IN SERBIAN LANGUAGE IN CHILDREN WITH SPEECH PATHOLOGY.

    Science.gov (United States)

    Dmitrić, Tanja; Veselinović, Mila; Mitrović, Slobodan M

    2015-01-01

    Articulation is the result of speech organs and it means clean, clear and distinct pronunciation of voices in words. A prospective study included 24 children between 5 and 15 years of age, of both sexes. All children were monolingual, Serbian being their native language. The quality of articulation was tested with Triage articulation test. Neither omission nor distortion of plosives was observed in any of them, whereas substitution of plosives occurred in 12% of patients. Omission of affricates was not observed in any of the subjects, but substitution and distortion occurred in 29%, and 76% of subjects, respectively. Omission of fricatives was found in 29% subjects, substitution in 52%, and distortion in 82% of subjects. Omission and distortion of nasals was not recorded in any of the subjects, and substitution occurred in 6% of children. Omission of laterals was observed in 6%, substitution in 46% and distortion in 52% of subjects with articulation disorders. Discussion and Articulation disorders were observed not only in children diagnosed with dyslalia but in those with dysphasia and stuttering as well. Children with speech disorders articulate vowels best, then nasals and plosives. Articulation of fricatives and laterals was found to be most severely deviated, including all three disorders, i.e. substitution, omission and distortion. Spasms of speech muscles and vegetative reactions were also observed in this study, but only in children with stuttering.

  10. How promotions work : SCAN*PRO-based evolutionary model building

    NARCIS (Netherlands)

    van Heerde, H.J.; Leeflang, P.S.H.; Wittink, D.R.

    2002-01-01

    We provide a rationale for evolutionary model building. The basic idea is that to enhance user acceptance it is important that one begins with a relatively simple model. Simplicity is desired so that managers understand models. As a manager uses the model and builds up experience with this decision

  11. [The Articulator of Primary Health Care Program: an innovative proposal for qualification of Primary Health Care].

    Science.gov (United States)

    Doricci, Giovanna Cabral; Guanaes-Lorenzi, Carla; Pereira, Maria José Bistafa

    2017-06-01

    In 2009, the Secretary of State for Health of Sao Paulo created a Program with a view to qualify the primary care in the state. This proposal includes a new job function, namely the articulator of primary care. Due to the scarcity of information about the practice of these new professionals in the scientific literature, this article seeks to analyze how articulators interpret their function and how they describe their daily routines. Thirteen articulators were interviewed. The interviews were duly analyzed by qualitative delineation. The results describe three themes: 1)Roles of the articulator: technical communicator and political advisor; 2) Activities performed to comply with the expected roles, examples being diagnosis of the municipalities, negotiation of proposals, participation in meetings, visits to municipalities; and 3) Challenges of the role, which are configured as challenges to the health reform process, examples being the lack of physical and human resources, activities of professionals in the medical-centered model, among others. The conclusion drawn is that the Program has great potential to provide input for the development and enhancement of Primary Care. Nevertheless, there are a series of challenges to be overcome, namely challenges to the context per se.

  12. Assessing the Impacts of Wool Promotion An Equilibrium Displacement Modelling Approach

    OpenAIRE

    1995-01-01

    The main goal of the International Wool Secretariat (IWS) is to increase the world demand for wool through promotion activities. Australia is a leading wool producer and the world's largest apparel wool exporter. Each year Australian wool producers contribute millions of dollars to the IWS for wool promotion. The principal aims of this paper are to demonstrate the potential for equilibrium displacement modelling to assess the impact of incremental wool promotion on wool producer incomes and p...

  13. Latino children's health and the family-community health promotion model.

    OpenAIRE

    Mendoza, F S; Fuentes-Afflick, E.

    1999-01-01

    A majority of Latino children in the US live in poverty. However, unlike other poor children, Latino children do not seem to have a consistent association between poverty and poor health. Instead, many poor Latino children have unexpectedly good health outcomes. This has been labeled an epidemiologic paradox. This paper proposes a new model of health, the family-community health promotion model, to account for this paradox. The family-community health promotion model emphasizes the family-com...

  14. The communicative action and information: a learning to learn transdisciplinary model

    Directory of Open Access Journals (Sweden)

    Márcia Marques

    2015-09-01

    Full Text Available This article is about the communicative action and information model for social networking in digital environments, a transdisciplinary articulation of knowledge and learning that guides the collective and collaborative construction of inclusive communication strategies and ongoing development of competencies to promote understanding between the players, members of a social network. Information Science, Communication itself and Information and Communication Technologies (ICT promote this articulation in transdisciplinary mode. This model is the basis for the diagnosis and action planning herein: for the collective construction of communication relationships negotiated between participants of the network; for the creation of digital environments that provide spaces for learning to cope with information and communication; so that public communication experts may promote transparency of information as stated in the Constitution and the Law on Access to Information in Brazil. The model articulates methodologies for analyses of the individual and the network (Users Study, Social Network Analysis, multivoicedness to obtain diagnosis and elaborate communication and information action planning.

  15. Modeling dynamic effects of promotion on interpurchase times

    NARCIS (Netherlands)

    D. Fok (Dennis); R. Paap (Richard); Ph.H.B.F. Franses (Philip Hans)

    2002-01-01

    textabstractIn this paper we put forward a duration model to analyze the dynamic effects of marketing-mix variables on interpurchase times. We extend the accelerated failure-time model with an autoregressive structure. An important feature of our model is that it allows for different long-run and

  16. Modeling dynamic effects of promotion on interpurchase times

    NARCIS (Netherlands)

    D. Fok (Dennis); R. Paap (Richard); Ph.H.B.F. Franses (Philip Hans)

    2002-01-01

    textabstractIn this paper we put forward a duration model to analyze the dynamic effects of marketing-mix variables on interpurchase times. We extend the accelerated failure-time model with an autoregressive structure. An important feature of our model is that it allows for different long-run and

  17. Articulating a Hermeneutic Pedagogy: The Philosophy of Interpretation.

    Science.gov (United States)

    Sotirou, Peter

    1993-01-01

    Articulates the salient features of a hermeneutic pedagogy as utilized in a composition classroom. Foregrounds the hermeneutical conclusions of Hans-Georg Gadamer as they relate to the teaching of writing. (HB)

  18. King County Metro Transit Hybrid Articulated Buses: Final Evaluation Results

    Energy Technology Data Exchange (ETDEWEB)

    Chandler, K.; Walkowicz, K.

    2006-12-01

    Final technical report compares and evaluates new diesel and diesel hybrid-electric articulated buses operated as part of the King County Metro Transit (KC Metro) fleet in Seattle, Washington. The evaluation lasted 12 months.

  19. A Hand-Eye Vision Measuring System for Articulate Robots

    Institute of Scientific and Technical Information of China (English)

    岁波; 都东; 陈强; 韩翔宇; 王力; 张骅

    2004-01-01

    To make dynamic measurements for an articulate robot, a hand-eye vision measuring system is built up.This system uses two charge coupled device (CCD) cameras mounted on the end-effector of the robot.System analysis is based on the stereovision theory and line-matching technology, using a computer to evaluate the dynamic performance parameters of an articulate robot from the two images captured by the two cameras.The measuring procedure includes four stages, namely, calibration, sampling, image processing, and calculation.The path accuracy of an articulate industrial robot was measured by this system.The results show that this system is a low-cost, easy to operate, and simple system for the dynamic performance testing of articulate robots.

  20. An Innovative Dialogue about College Drinking: Developing an Immediate Response Technology Model for Health Promotion

    Science.gov (United States)

    LeGreco, Marianne; Hess, Aaron; Lederman, Linda C.; Schuwerk, Tara; LaValley, Angela G.

    2010-01-01

    New communication technologies, including personal response "clickers," have become increasingly popular across college campuses as a way to promote a wide range of practices. This paper calls attention to the need for communication models that account for the usefulness of these new technologies, especially as they relate to health promotion,…

  1. Revisiting Precede-Proceed: A Leading Model for Ecological and Ethical Health Promotion

    Science.gov (United States)

    Porter, Christine M.

    2016-01-01

    Background: The Precede-Proceed model has provided moral and practical guidance for the fields of health education and health promotion since Lawrence Green first developed Precede in 1974 and Green and Kreuter added Proceed in 1991. Precede-Proceed today remains the most comprehensive and one of the most used approaches to promoting health.…

  2. Targeting and timing promotional activities : An agent-based model for the takeoff of new products

    NARCIS (Netherlands)

    Delre, S. A.; Jager, W.; Bijmolt, T. H. A.; Janssen, M. A.

    2007-01-01

    Many marketing efforts focus on promotional activities that support the launch of new products. Promotional strategies may play a crucial role in the early stages of the product life cycle, and determine to a large extent the diffusion of a new product. This paper proposes an agent-based model to si

  3. Targeting and timing promotional activities : An agent-based model for the takeoff of new products

    NARCIS (Netherlands)

    Delre, S. A.; Jager, W.; Bijmolt, T. H. A.; Janssen, M. A.

    Many marketing efforts focus on promotional activities that support the launch of new products. Promotional strategies may play a crucial role in the early stages of the product life cycle, and determine to a large extent the diffusion of a new product. This paper proposes an agent-based model to

  4. Measuring Short- and Long-run Promotional Effectiveness on Scanner Data Using Persistence Modeling

    NARCIS (Netherlands)

    M.G. Dekimpe (Marnik); D.M. Hanssens (Dominique); V.R. Nijs; J-B.E.M. Steenkamp (Jan-Benedict)

    2003-01-01

    textabstractThe use of price promotions to stimulate brand and firm performance is increasing. We discuss how (i) the availability of longer scanner data time series, and (ii) persistence modeling, have lead to greater insights into the dynamic effects of price promotions, as one can now quantify th

  5. Finding Strong Bridges and Strong Articulation Points in Linear Time

    Science.gov (United States)

    Italiano, Giuseppe F.; Laura, Luigi; Santaroni, Federico

    Given a directed graph G, an edge is a strong bridge if its removal increases the number of strongly connected components of G. Similarly, we say that a vertex is a strong articulation point if its removal increases the number of strongly connected components of G. In this paper, we present linear-time algorithms for computing all the strong bridges and all the strong articulation points of directed graphs, solving an open problem posed in [2].

  6. EXPERIMENTAL EVALUATION OF ARTICULATED WHEELED VEHICLES POSITION STABILITY

    Directory of Open Access Journals (Sweden)

    Ye. Dubinin

    2015-07-01

    Full Text Available With introducing a mobile measurement system with linear acceleration sensors there was experimentally determined the parameter of position stability of the articulated wheeled vehicle on the example of HTA-200 «Slobozhanets». It was determined that the position stability was provided within the entire range of operating speeds and accelerations. The obtained results can be used to enhance the traffic safety of articulated vehicles.

  7. Refreshing Information Literacy: Learning from Recent British Information Literacy Models

    Science.gov (United States)

    Martin, Justine

    2013-01-01

    Models play an important role in helping practitioners implement and promote information literacy. Over time models can lose relevance with the advances in technology, society, and learning theory. Practitioners and scholars often call for adaptations or transformations of these frameworks to articulate the learning needs in information literacy…

  8. Virtual articulator for the analysis of dental occlusion: an update.

    Science.gov (United States)

    Maestre-Ferrín, Laura; Romero-Millán, Javier; Peñarrocha-Oltra, David; Peñarrocha-Diago, María

    2012-01-01

    The future of dental practice is closely linked to the utilization of computer-based technology, specifically virtual reality, which allows the dental surgeon to simulate true life situations in patients. The virtual articulator has been designed for the exhaustive analysis of static and dynamic occlusion, with the purpose of substituting mechanical articulators and avoiding their errors. These tools will help both odontologists and dental prosthetists to provide the best individualized treatment for each patient. The present review analyzes the studies published in the literature on the design, functioning and applications of virtual articulators. A Medline-PubMed search was made of dental journals, with the identification of 137 articles, of which 16 were finally selected. The virtual articulator can simulate the specific masticatory movement of the patient. During mandibular animation, the program calculates the sites where the opposing teeth come into contact. The studies made to assess the reliability of the virtual articulator show good correspondence in visualization of the number and position of the dynamic contacts. The virtual articulator is a precise tool for the full analysis of occlusion in a real patient.

  9. Sinkage and slippage estimation for an articulated vehicle

    Science.gov (United States)

    Wilcox, Brian H.

    2002-07-01

    This paper describes an approach to estimating in real-time the degree to which an articulated robotic vehicle is undergoing wheel slip and/or sinkage in soft terrain. Robotic vehicles generally have hazard avoidance sensors which measure the shape of the sensible surface, and these can be used to predict what the articulation pose of the vehicle will be as it moves over the surface. An articulated vehicle (one with three or more wheels on each side) can directly measure the shape of the loadbearing surface by combining inclination and articulation sensing. Delays between the actual articulations and the expectations can be explained by wheel slippage. Differences between the expectation and the actual articulations can be explained by sinkage below the sensed surface. If one assumes that successive wheels on each side follow the same profile as the front wheel (sinking the same amount, if any, into the soil), then it is possible to estimate sinkage and slippage separately. A Maximum-A-Posteriori estimation procedure formalizing this heuristic approach is developed and simulated, and the results presented and discussed.

  10. Using Virtual Pets to Promote Physical Activity in Children: An Application of the Youth Physical Activity Promotion Model.

    Science.gov (United States)

    Ahn, Sun Joo Grace; Johnsen, Kyle; Robertson, Tom; Moore, James; Brown, Scott; Marable, Amanda; Basu, Aryabrata

    2015-01-01

    A virtual pet was developed based on the framework of the youth physical activity promotion model and tested as a vehicle for promoting physical activity in children. Children in the treatment group interacted with the virtual pet for three days, setting physical activity goals and teaching tricks to the virtual pet when their goals were met. The virtual pet became more fit and learned more sophisticated tricks as the children achieved activity goals. Children in the control group interacted with a computer system presenting equivalent features but without the virtual pet. Physical activity and goal attainment were evaluated using activity monitors. Results indicated that children in the treatment group engaged in 1.09 more hours of daily physical activity (156% more) than did those in the control group. Physical activity self-efficacy and beliefs served as mediators driving this increase in activity. Children that interacted with the virtual pet also expressed higher intentions than children in the control group to continue physical activity in the future. Theoretical and practical potentials of using a virtual pet to systematically promote physical activity in children are discussed.

  11. Hydrostatic Pressure Promotes Domain Formation in Model Lipid Raft Membranes.

    Science.gov (United States)

    Worcester, David L; Weinrich, Michael

    2015-11-01

    Neutron diffraction measurements demonstrate that hydrostatic pressure promotes liquid-ordered (Lo) domain formation in lipid membranes prepared as both oriented multilayers and unilamellar vesicles made of a canonical ternary lipid mixture for which demixing transitions have been extensively studied. The results demonstrate an unusually large dependence of the mixing transition on hydrostatic pressure. Additionally, data at 28 °C show that the magnitude of increase in Lo caused by 10 MPa pressure is much the same as the decrease in Lo produced by twice minimum alveolar concentrations (MAC) of general anesthetics such as halothane, nitrous oxide, and xenon. Therefore, the results may provide a plausible explanation for the reversal of general anesthesia by hydrostatic pressure.

  12. An ANN-GA model based promoter prediction in Arabidopsis thaliana using tilling microarray data

    Science.gov (United States)

    Mishra, Hrishikesh; Singh, Nitya; Misra, Krishna; Lahiri, Tapobrata

    2011-01-01

    Identification of promoter region is an important part of gene annotation. Identification of promoters in eukaryotes is important as promoters modulate various metabolic functions and cellular stress responses. In this work, a novel approach utilizing intensity values of tilling microarray data for a model eukaryotic plant Arabidopsis thaliana, was used to specify promoter region from non-promoter region. A feed-forward back propagation neural network model supported by genetic algorithm was employed to predict the class of data with a window size of 41. A dataset comprising of 2992 data vectors representing both promoter and non-promoter regions, chosen randomly from probe intensity vectors for whole genome of Arabidopsis thaliana generated through tilling microarray technique was used. The classifier model shows prediction accuracy of 69.73% and 65.36% on training and validation sets, respectively. Further, a concept of distance based class membership was used to validate reliability of classifier, which showed promising results. The study shows the usability of micro-array probe intensities to predict the promoter regions in eukaryotic genomes. PMID:21887014

  13. Evaluation of Two Facebow/Semi-adjustable Articulator Systems for Orienting Maxillary Cast on Articulators: A Pilot Study

    National Research Council Canada - National Science Library

    Anusha, C V; Singh, Amith A; Sam, George; Sangwan, Babita; Shilpa, M; Kamath, Akshata G

    2016-01-01

    The present study was aimed to assess the transferability of occlusal plane (OP) orientation from the patient to the articulators with the help of two different facebow systems and evaluated with a gold standard...

  14. PENGEMBANGAN MODEL SEKOLAH SEHAT (HEALTH PROMOTING SCHOOL DI DAERAH MISKIN PERKOTAAN

    Directory of Open Access Journals (Sweden)

    Andryansyah Arifin

    2012-11-01

    Full Text Available It is known that there was strong relation between health status of primary school students and school records. A health­ promoting school was, whether all members of school community work together to provide students with an integrated positive experiences and structures which promote and protect their health.These include both formal and informal curriculum in health, creation of a safe and healthy school environment, provision of appropriate health services and involvement of family and wider commmunities was in efforts to promote health. The objectives of, this study is to develop a model of health promoting school at poor urban areas which included to measure student knowledge and attitude, nutrition intake, and role of school teacher in health promotion. A stratified mulitistage randomized pre-post test control groups design was used in this study. Duration of this study was 3 years (2001-2003 and the location at 9 primary schools (6 intervention schools and 3 control schools in Semarang, Surakarta, Denpasar municipalities and Kendal district. Results of this study showed that students knowledge and atitude toward health were improved significantly as well as nutrition intake at intervention groups. This improvement was caused by the role of school teachers in health promotion which was integrated in daily learning process. Based on this results a model of health promoting school has been developed. It recommends to implement this health promoting school model at wider areas and to provide school teachers completed with health promotion manuals.   Keywords: model, health promoting school

  15. Metabolic Trade-Offs Promote Diversity in a Model Ecosystem

    Science.gov (United States)

    Posfai, Anna; Taillefumier, Thibaud; Wingreen, Ned S.

    2017-01-01

    In nature, a large number of species can coexist on a small number of shared resources; however, resource-competition models predict that the number of species in steady coexistence cannot exceed the number of resources. Motivated by recent studies of phytoplankton, we introduce trade-offs into a resource-competition model and find that an unlimited number of species can coexist. Our model spontaneously reproduces several notable features of natural ecosystems, including keystone species and population dynamics and abundances characteristic of neutral theory, despite an underlying non-neutral competition for resources.

  16. Promoting and Supporting Scientific Argumentation in the Classroom: The Evaluate-Alternatives Instructional Model

    Science.gov (United States)

    Sampson, Victor; Grooms, Jonathon

    2009-01-01

    This article describes an instructional model that science teachers can use to promote and support student engagement in scientific argumentation. This model is called the evaluate-alternatives instructional model and it is grounded in current research on argumentation in science education (e.g., Berland and Reiser 2009; McNeill and Krajcik 2006;…

  17. Computer-assisted three-dimensional surgical planning: 3D virtual articulator: technical note.

    Science.gov (United States)

    Ghanai, S; Marmulla, R; Wiechnik, J; Mühling, J; Kotrikova, B

    2010-01-01

    This study presents a computer-assisted planning system for dysgnathia treatment. It describes the process of information gathering using a virtual articulator and how the splints are constructed for orthognathic surgery. The deviation of the virtually planned splints is shown in six cases on the basis of conventionally planned cases. In all cases the plaster models were prepared and scanned using a 3D laser scanner. Successive lateral and posterior-anterior cephalometric images were used for reconstruction before surgery. By identifying specific points on the X-rays and marking them on the virtual models, it was possible to enhance the 2D images to create a realistic 3D environment and to perform virtual repositioning of the jaw. A hexapod was used to transfer the virtual planning to the real splints. Preliminary results showed that conventional repositioning could be replicated using the virtual articulator.

  18. The Effect of Inflated Backrest Stiffness on Shearing Loads Estimated with Articulated Total Body

    CERN Document Server

    Scurlock, Bob J; Borsa, Paul A

    2013-01-01

    In the construction of simulations of rear-end vehicle impacts, the Articulated Total Body (ATB) software package can be a useful tool. In this article we discuss the effect of using artificially inflated values for seat-backrest stiffness in ATB simulations. We will also present methods for quickly assessing the quality of simulation results. In this connection, we will discuss the perils of using the default contact-force models that are included in ATB package releases.

  19. Assessment of organizational readiness for health promotion policy implementation: test of a theoretical model.

    Science.gov (United States)

    Rütten, A; Röger, U; Abu-Omar, K; Frahsa, A

    2009-09-01

    Models explaining the engagement of organizations in different policy sectors in health promotion policy implementation often utilize retrospective data. The current study attempted to model determinants of organizational readiness (goals, resources, obligation, opportunities) in supporting health policy implementation prospectively. Twenty qualitative interviews with representatives of organizations from different policy sectors, levels of government and organizational legal entities were conducted at the beginning of a project for the promotion of physical activity among women in difficult life situations. Organizational support in developing, implementing and disseminating the project was documented over 36 months. Results indicated that in most organizations, determinants were not favorable for health promotion policy action for physical activity among women in difficult life situations. Six organizations did not report any favorable determinant, and two organizations reported four. The other 12 organizations reported positive results for some of the determinants. Project work received support from 6 out of the 20 organizations. A case study of three organizations indicated that engagement or disengagement of organizations in health promotion policy actions might be partly explained by the theoretical model. The prospective assessment of organizational readiness in implementing health promotion policy is highly relevant for health promotion. Considering the proposed theoretical framework may aid in advancing our understanding of factors that are related to organizational engagement in health promotion actions.

  20. Promoting Representational Competence with Molecular Models in Organic Chemistry

    Science.gov (United States)

    Stull, Andrew T.; Gainer, Morgan; Padalkar, Shamin; Hegarty, Mary

    2016-01-01

    Mastering the many different diagrammatic representations of molecules used in organic chemistry is challenging for students. This article summarizes recent research showing that manipulating 3-D molecular models can facilitate the understanding and use of these representations. Results indicate that students are more successful in translating…

  1. Promoting Representational Competence with Molecular Models in Organic Chemistry

    Science.gov (United States)

    Stull, Andrew T.; Gainer, Morgan; Padalkar, Shamin; Hegarty, Mary

    2016-01-01

    Mastering the many different diagrammatic representations of molecules used in organic chemistry is challenging for students. This article summarizes recent research showing that manipulating 3-D molecular models can facilitate the understanding and use of these representations. Results indicate that students are more successful in translating…

  2. Discovering and Articulating What Is Not yet Known: Using Action Learning and Grounded Theory as a Knowledge Management Strategy

    Science.gov (United States)

    Pauleen, David J.; Corbitt, Brian; Yoong, Pak

    2007-01-01

    Purpose: To provide a conceptual model for the discovery and articulation of emergent organizational knowledge, particularly knowledge that develops when people work with new technologies. Design/methodology/approach: The model is based on two widely accepted research methods--action learning and grounded theory--and is illustrated using a case…

  3. Digital Hardware Realization of Forward and Inverse Kinematics for a Five-Axis Articulated Robot Arm

    Directory of Open Access Journals (Sweden)

    Bui Thi Hai Linh

    2015-01-01

    Full Text Available When robot arm performs a motion control, it needs to calculate a complicated algorithm of forward and inverse kinematics which consumes much CPU time and certainty slows down the motion speed of robot arm. Therefore, to solve this issue, the development of a hardware realization of forward and inverse kinematics for an articulated robot arm is investigated. In this paper, the formulation of the forward and inverse kinematics for a five-axis articulated robot arm is derived firstly. Then, the computations algorithm and its hardware implementation are described. Further, very high speed integrated circuits hardware description language (VHDL is applied to describe the overall hardware behavior of forward and inverse kinematics. Additionally, finite state machine (FSM is applied for reducing the hardware resource usage. Finally, for verifying the correctness of forward and inverse kinematics for the five-axis articulated robot arm, a cosimulation work is constructed by ModelSim and Simulink. The hardware of the forward and inverse kinematics is run by ModelSim and a test bench which generates stimulus to ModelSim and displays the output response is taken in Simulink. Under this design, the forward and inverse kinematics algorithms can be completed within one microsecond.

  4. ProMT: effective human promoter prediction using Markov chain model based on DNA structural properties.

    Science.gov (United States)

    Xiong, Dapeng; Liu, Rongjie; Xiao, Fen; Gao, Xieping

    2014-12-01

    The core promoters play significant and extensive roles for the initiation and regulation of DNA transcription. The identification of core promoters is one of the most challenging problems yet. Due to the diverse nature of core promoters, the results obtained through existing computational approaches are not satisfactory. None of them considered the potential influence on performance of predictive approach resulted by the interference between neighboring TSSs in TSS clusters. In this paper, we sufficiently considered this main factor and proposed an approach to locate potential TSS clusters according to the correlation of regional profiles of DNA and TSS clusters. On this basis, we further presented a novel computational approach (ProMT) for promoter prediction using Markov chain model and predictive TSS clusters based on structural properties of DNA. Extensive experiments demonstrated that ProMT can significantly improve the predictive performance. Therefore, considering interference between neighboring TSSs is essential for a wider range of promoter prediction.

  5. A newer technique to program a semi adjustable articulator

    Directory of Open Access Journals (Sweden)

    R Venkateshwaran

    2014-01-01

    Full Text Available Introduction: The difficulty in reproducing accurate angle of condylar guidance in semi-adjustable articulators. Purpose: The purpose of this study was to determine the correlation between the angle of horizontal condylar inclination obtained on a semi-adjustable articulator and the corresponding angle traced on a temporomandibular joint (TMJ radiograph in completely edentulous subject. Materials and Methods: The horizontal condylar inclination angle was obtained in a semi-adjustable articulator by means of height tracer (extra oral tracing device and interocclusal records to program the articulator in 21 subjects. TMJ radiograph were recorded by the same operator with same orthopantomogram (OPG machine (planmeca. Tracings of inclines of articular eminence on the radiograph were compared with the angle obtained on a semi-adjustable articulator. Each measurement was made using manual methods of measuring angle. The results were subjected to the Pearson correlation statistical analysis (α =0.01. Results: The outline of the articular eminence in a TMJ tomogram radiographic image was identified and traced. A significant correlation was found between the horizontal condylar inclination on a semi-adjustable and the corresponding TMJ tomogram radiographic image for both right (R = 0.789; P = 0.001 and left (i = 0.747; P = 0.004 sides. Conclusion: The articular eminence traced on a TMJ tomogram image represents the horizontal condylar inclination with a mean difference of 5° in 21 subjects evaluated.

  6. Compensation and Promotion Models: A New Econometrics Approach

    Science.gov (United States)

    2010-01-29

    m itjmw 1 M itj itjm m m w v    1,1itj    1,1mv The Information Theoretic, General Maximum Entropy (IT-GME) Model: (Maximizing the joint...that may contradict economic intuition/theory. • From a practical point of view, a number of researchers show that the multivariate (or bivariate ... entropies of the signal and noise subject to the linear cross moments, First Order Markov conditions, and the requirements that w are proper

  7. Characterization and identification of microRNA core promoters in four model species.

    Directory of Open Access Journals (Sweden)

    Xuefeng Zhou

    2007-03-01

    Full Text Available MicroRNAs are short, noncoding RNAs that play important roles in post-transcriptional gene regulation. Although many functions of microRNAs in plants and animals have been revealed in recent years, the transcriptional mechanism of microRNA genes is not well-understood. To elucidate the transcriptional regulation of microRNA genes, we study and characterize, in a genome scale, the promoters of intergenic microRNA genes in Caenorhabditis elegans, Homo sapiens, Arabidopsis thaliana, and Oryza sativa. We show that most known microRNA genes in these four species have the same type of promoters as protein-coding genes have. To further characterize the promoters of microRNA genes, we developed a novel promoter prediction method, called common query voting (CoVote, which is more effective than available promoter prediction methods. Using this new method, we identify putative core promoters of most known microRNA genes in the four model species. Moreover, we characterize the promoters of microRNA genes in these four species. We discover many significant, characteristic sequence motifs in these core promoters, several of which match or resemble the known cis-acting elements for transcription initiation. Among these motifs, some are conserved across different species while some are specific to microRNA genes of individual species.

  8. Extracting hand articulations from monocular depth images using curvature scale space descriptors

    Institute of Scientific and Technical Information of China (English)

    Shao-fan WANG[1; Chun LI[1; De-hui KONG[1; Bao-cai YIN[2,1,3

    2016-01-01

    We propose a framework of hand articulation detection from a monocular depth image using curvature scale space (CSS) descriptors. We extract the hand contour from an input depth image, and obtain the fingertips and finger-valleys of the contour using the local extrema of a modified CSS map of the contour. Then we recover the undetected fingertips according to the local change of depths of points in the interior of the contour. Compared with traditional appearance-based approaches using either angle detectors or convex hull detectors, the modified CSS descriptor extracts the fingertips and finger-valleys more precisely since it is more robust to noisy or corrupted data; moreover, the local extrema of depths recover the fingertips of bending fingers well while traditional appearance-based approaches hardly work without matching models of hands. Experimental results show that our method captures the hand articulations more precisely compared with three state-of-the-art appearance-based approaches.

  9. Extracting hand articulations from monocular depth images using curvature scale space descriptors

    Institute of Scientific and Technical Information of China (English)

    Shao-fan WANG; Chun LI; De-hui KONG; Bao-cai YIN

    2016-01-01

    We propose a framework of hand articulation detection from a monocular depth image using curvature scale space (CSS) descriptors. We extract the hand contour from an input depth image, and obtain the fingertips and finger-valleys of the contour using the local extrema of a modified CSS map of the contour. Then we recover the undetected fingertips according to the local change of depths of points in the interior of the contour. Compared with traditional appearance-based approaches using either angle detectors or convex hull detectors, the modified CSS descriptor extracts the fingertips and finger-valleys more precisely since it is more robust to noisy or corrupted data;moreover, the local extrema of depths recover the fingertips of bending fingers well while traditional appearance-based approaches hardly work without matching models of hands. Experimental results show that our method captures the hand articulations more precisely compared with three state-of-the-art appearance-based approaches.

  10. Assessing the effect of physical differences in the articulation of consonants and vowels on audiovisual temporal perception

    Science.gov (United States)

    Vatakis, Argiro; Maragos, Petros; Rodomagoulakis, Isidoros; Spence, Charles

    2012-01-01

    We investigated how the physical differences associated with the articulation of speech affect the temporal aspects of audiovisual speech perception. Video clips of consonants and vowels uttered by three different speakers were presented. The video clips were analyzed using an auditory-visual signal saliency model in order to compare signal saliency and behavioral data. Participants made temporal order judgments (TOJs) regarding which speech-stream (auditory or visual) had been presented first. The sensitivity of participants' TOJs and the point of subjective simultaneity (PSS) were analyzed as a function of the place, manner of articulation, and voicing for consonants, and the height/backness of the tongue and lip-roundedness for vowels. We expected that in the case of the place of articulation and roundedness, where the visual-speech signal is more salient, temporal perception of speech would be modulated by the visual-speech signal. No such effect was expected for the manner of articulation or height. The results demonstrate that for place and manner of articulation, participants' temporal percept was affected (although not always significantly) by highly-salient speech-signals with the visual-signals requiring smaller visual-leads at the PSS. This was not the case when height was evaluated. These findings suggest that in the case of audiovisual speech perception, a highly salient visual-speech signal may lead to higher probabilities regarding the identity of the auditory-signal that modulate the temporal window of multisensory integration of the speech-stimulus. PMID:23060756

  11. [An Experience Promoting the Interdisciplinary Care Model for Dengue Fever].

    Science.gov (United States)

    Kuo, Wen-Fu; Ke, Ya-Ting

    2016-08-01

    Emergency departments represent the first line in facing major healthcare events. During major epidemic outbreaks, patients crowding into the emergency departments increase the wait time for patients and overload the staffs that are on duty. The dengue fever outbreak in southern Taiwan during the summer 2015 presented a huge management challenge for physicians and nurses in local hospitals. We responded to this challenge by integrating resources from different hospital departments. This strategy successfully increased group cohesiveness among the medical team, ensuring that they could not only ultimately cope with the outbreak together but also effectively provide patient-centered care. This interdisciplinary care model may serve as a reference for medical professionals for the management of future epidemics and similar events.

  12. Structural Equation Model of Health Promoting Behaviors for Health Information Seekers with Mobile.

    Science.gov (United States)

    Choi, Hanna; Kim, Jeongeun; Byun, Ahjung

    2016-01-01

    This study was conducted on verifying whether variables such as prior health related behaviors, health literacy, interpersonal influence, perceived ease of use and usefulness of health information, and behavioral intention could predict actual health promoting behaviors of consumers using health information with mobile in the future. The research model was based on Technology Acceptance Model. Data were collected from 199 mobile health information seekers. Participants' actual health promoting behaviors were checked after 3 months from pre-data collection. The final modified model had good fit indices.

  13. Planar articulated mechanism design by graph theoretical enumeration

    DEFF Research Database (Denmark)

    Kawamoto, A; Bendsøe, Martin P.; Sigmund, Ole

    2004-01-01

    This paper deals with design of articulated mechanisms using a truss-based ground-structure representation. By applying a graph theoretical enumeration approach we can perform an exhaustive analysis of all possible topologies for a test example for which we seek a symmetric mechanism. This guaran......This paper deals with design of articulated mechanisms using a truss-based ground-structure representation. By applying a graph theoretical enumeration approach we can perform an exhaustive analysis of all possible topologies for a test example for which we seek a symmetric mechanism....... This guarantees that one can identify the global optimum solution. The result underlines the importance of mechanism topology and gives insight into the issues specific to articulated mechanism designs compared to compliant mechanism designs....

  14. [Empowering the family-center health model: the toy library as a health promotion platform].

    Science.gov (United States)

    Huang, Yu-Chu; Tsai, Yen-Chih

    2011-02-01

    Facing the lowest birth rates in its history, Taiwan is increasingly recognizing the centrality of children's healthcare needs to effective family care. The World Health Organization's goal of health for all emphasizes health promotion. However, little research attention has been given to how families actively promote personal health in everyday life. This article considers 'family-centric' healthcare, with a particular emphasis on children's health and well-being and the mother health promotion model. Authors employ a 'toy library' as the health promotion platform to build community interaction and empower the health enhancement process. Results suggested the following: 1. The fixed-point type toy library may be an effective tool in a health promotion strategy; 2. A model may be developed for rural institution agencies; 3. Cooperation may be facilitated using a medical service vehicle; 4. The love bag program can serve extended purposes. The authors found that the empowerment and growth of tribal mothers is a key element to facilitate the successful development of their children. Based on findings, the implementation of a toy library as the platform to build community-based health promotion model is suggested.

  15. Promoting Conceptual Coherence in Quantum Learning through Computational Models

    Science.gov (United States)

    Lee, Hee-Sun

    2012-02-01

    In order to explain phenomena at the quantum level, scientists use multiple representations in verbal, pictorial, mathematical, and computational forms. Conceptual coherence among these multiple representations is used as an analytical framework to describe student learning trajectories in quantum physics. A series of internet-based curriculum modules are designed to address topics in quantum mechanics, semiconductor physics, and nano-scale engineering applications. In these modules, students are engaged in inquiry-based activities situated in a highly interactive computational modeling environment. This study was conducted in an introductory level solid state physics course. Based on in-depth interviews with 13 students, methods for identifying conceptual coherence as a function of students' level of understanding are presented. Pre-post test comparisons of 20 students in the course indicate a statistically significant improvement in students' conceptual coherence of understanding quantum phenomena before and after the course, Effect Size = 1.29 SD. Additional analyses indicate that students who responded to the modules more coherently improved their conceptual coherence to a greater extent than those who did less to the modules after controlling for their course grades.

  16. Modeling mechanical effects on promotion and retardation of martensitic transformation

    Energy Technology Data Exchange (ETDEWEB)

    Maalekian, Mehran, E-mail: mehran.maalekian@ubc.ca [Department of Materials Engineering, University of British Columbia, 309-6350 Stores Road, Vancouver, B.C. V61Z4 (Canada); Kozeschnik, Ernst [Christian Doppler Laboratory for ' Early Stages of Precipitation' , Institute of Materials Science and Technology, Vienna University of Technology (Austria)

    2011-01-25

    Research highlights: {yields} Compressive elastic stresses up to 250 MPa are applied in continuous cooling. {yields} Using the thermodynamic data and maximum value of the mechanical driving force the predicted increase in M{sub s} ({approx}0.1 K/MPa) is in agreement with experiment {yields} Austenite was deformed plastically at different temperatures (800 deg. C-1100 deg. C). {yields} High deformation temperature (i.e. 1100 deg. C) as well as low plastic strain (i.e. {epsilon}{sub ave} {approx} 30%) do not affect martensite transformation noticeably, whereas lower deformation temperature (e.g. 900 deg. C) and large plastic strain (i.e. {epsilon}{sub ave} {approx} 70%) retards martensite transformation. {yields} The theory of mechanical stabilization predicts the depression of M{sub s}. - Abstract: The influence of compressive stress and prior plastic deformation of austenite on the martensite transformation in a eutectoid steel is studied both experimentally and theoretically. It is demonstrated that martensite formation is assisted by stress but it is retarded when transformation occurs from deformed austenite. With the quantitative modeling of the problem based on the theory of displacive shear transformation, the explanation of the two opposite roles of mechanical treatment prior to or simultaneously to martensite transformation is presented.

  17. Swisstrolley 3 - An articulated trolley bus; SWISSTROLLEY 3. Gelenktrolleybus

    Energy Technology Data Exchange (ETDEWEB)

    Gisler, H.-J.

    2006-07-01

    This illustrated final report for the Swiss Federal Office of Energy (SFOE) takes a look at the Swisstrolley 3 low-floor, articulated trolley bus developed in Switzerland by the Hess AG company. Various features of the variants of the trolley bus, including single vehicle, single and double-articulated buses and bus trailers, are discussed. The reductions achieved in energy consumption, weight and noise are discussed. Typical values for power consumption are presented in graphical form. Economic viability and passenger-friendliness are examined, as are possibilities for further improvement.

  18. The Landscape of Mass Mediated Articulations of Biotechnology

    DEFF Research Database (Denmark)

    Horst, Maja

    The objective of this paper is to explore the associations made in mass mediatedarticulations of biotechnology. It serves as the basis for further analyses of massmediated controversies and the purpose is to establish a map of the landscape ofmass mediated articulation of biotechnology. Which kinds...... of genetic researchand technology are articulated in what way? What can be associated to what inthe mass mediation and when is it portrayed as controversial? In short this is astudy of associations in the news production that serves as a way of establishingan empirical archive for further work. It is based...

  19. A multi-scale model of hepcidin promoter regulation reveals factors controlling systemic iron homeostasis.

    Directory of Open Access Journals (Sweden)

    Guillem Casanovas

    2014-01-01

    Full Text Available Systemic iron homeostasis involves a negative feedback circuit in which the expression level of the peptide hormone hepcidin depends on and controls the iron blood levels. Hepcidin expression is regulated by the BMP6/SMAD and IL6/STAT signaling cascades. Deregulation of either pathway causes iron-related diseases such as hemochromatosis or anemia of inflammation. We quantitatively analyzed how BMP6 and IL6 control hepcidin expression. Transcription factor (TF phosphorylation and reporter gene expression were measured under co-stimulation conditions, and the promoter was perturbed by mutagenesis. Using mathematical modeling, we systematically analyzed potential mechanisms of cooperative and competitive promoter regulation by the transcription factors, and experimentally validated the model predictions. Our results reveal that hepcidin cross-regulation primarily occurs by combinatorial transcription factor binding to the promoter, whereas signaling crosstalk is insignificant. We find that the presence of two BMP-responsive elements enhances the steepness of the promoter response towards the iron-sensing BMP signaling axis, which promotes iron homeostasis in vivo. IL6 co-stimulation reduces the promoter sensitivity towards the BMP signal, because the SMAD and STAT transcription factors compete for recruiting RNA polymerase to the transcription start site. This may explain why inflammatory signals disturb iron homeostasis in anemia of inflammation. Taken together, our results reveal why the iron homeostasis circuit is sensitive to perturbations implicated in disease.

  20. Mesoscopic model and free energy landscape for protein-DNA binding sites: analysis of cyanobacterial promoters.

    Directory of Open Access Journals (Sweden)

    Rafael Tapia-Rojo

    2014-10-01

    Full Text Available The identification of protein binding sites in promoter sequences is a key problem to understand and control regulation in biochemistry and biotechnological processes. We use a computational method to analyze promoters from a given genome. Our approach is based on a physical model at the mesoscopic level of protein-DNA interaction based on the influence of DNA local conformation on the dynamics of a general particle along the chain. Following the proposed model, the joined dynamics of the protein particle and the DNA portion of interest, only characterized by its base pair sequence, is simulated. The simulation output is analyzed by generating and analyzing the Free Energy Landscape of the system. In order to prove the capacity of prediction of our computational method we have analyzed nine promoters of Anabaena PCC 7120. We are able to identify the transcription starting site of each of the promoters as the most populated macrostate in the dynamics. The developed procedure allows also to characterize promoter macrostates in terms of thermo-statistical magnitudes (free energy and entropy, with valuable biological implications. Our results agree with independent previous experimental results. Thus, our methods appear as a powerful complementary tool for identifying protein binding sites in promoter sequences.

  1. Critical incident stress debriefing: a health promotion model for workplace violence.

    Science.gov (United States)

    Antai-Otong, D

    2001-01-01

    To view the global impact of violence as a critical incident. Published literature, author's experience. Psychiatric nurses can use the critical incident stress debriefing protocol to minimize adverse outcomes after a traumatic event. Workplace violence threatens the safety and well-being of nurses. Psychiatric nurses are more likely to encounter workplace violence than nurses in other settings and must prepare themselves using proactive health-promoting activities, for example the critical incident stress debriefing (CISD) model. This health-promotion model provides immediate emotional support and education about normal stress reactions, and may reduce the risk of chronic and disabling emotional and physical consequences.

  2. Using Standardized Tests to Inventory Consonant and Vowel Production: A Comparison of 11 Tests of Articulation and Phonology

    Science.gov (United States)

    Eisenberg, Sarita L.; Hitchcock, Elaine R.

    2010-01-01

    Purpose: This report considered the validity of making conclusions about a child's phonetic inventory (the sounds a child can and cannot produce spontaneously without a prior model or other stimulation) based on the data from standardized single-word tests of articulation or phonology. Method: We evaluated the opportunities for production of…

  3. The Active Role of Instruments in Articulating Knowing and Knowledge: The Case of Animal Qualification Practices in Breeding Organisations

    Science.gov (United States)

    Labatut, Julie; Aggeri, Franck; Astruc, Jean-Michel; Bibe, Bernard; Girard, Nathalie

    2009-01-01

    Purpose: The purpose of this paper is to investigate the role of instruments defined as artefacts, rules, models or norms, in the articulation between knowing-in-practice and knowledge, in learning processes. Design/methodology/approach: The paper focuses on a distributed, knowledge-intensive and instrumented activity at the core of any collective…

  4. Using Standardized Tests to Inventory Consonant and Vowel Production: A Comparison of 11 Tests of Articulation and Phonology

    Science.gov (United States)

    Eisenberg, Sarita L.; Hitchcock, Elaine R.

    2010-01-01

    Purpose: This report considered the validity of making conclusions about a child's phonetic inventory (the sounds a child can and cannot produce spontaneously without a prior model or other stimulation) based on the data from standardized single-word tests of articulation or phonology. Method: We evaluated the opportunities for production of…

  5. College Level One: Articulation, Equity, and Literacy Issues. Workshop Report.

    Science.gov (United States)

    Bisgaard, Soren; Brillhart, Lia V.; Burgess, Ann B.; Cramer, Jane Harris; Denton, Denice D.; Downer, Janice D.; Dunwoody, Sharon L.; Ellis, Arthur B.; Hewson, Peter W.; Secada, Walter G.; Tobias, Sheila

    This document reports on a workshop entitled "Articulation, Equity, and Literacy Issues" hosted by the College Level One (CL-1) project of the National Institute for Science Education (NISE). CL-1 identifies important issues in undergraduate education and determines the best strategies for addressing them. Workshop discussions examine…

  6. Articulating the International Curriculum. Part II, Continuity through Outcomes.

    Science.gov (United States)

    Bartlett, Kevin

    1997-01-01

    The three programs now offered by the International Baccalaureate Organization for children 5 to 18 could benefit from greater articulation. The programs share common goals aimed at developing in students sense of responsibility, spirit of open-mindedness, critical thinking ability, multilanguage proficiency, and active interest in other cultures.…

  7. Larval Myogenesis in the Articulate Brachiopod Argyrotheca cordata (Risso, 1826)

    DEFF Research Database (Denmark)

    Altenburger, Andreas; Wanninger, Andreas Wilhelm Georg

    2008-01-01

    and micromorphological data to this debate, we investigated muscle formation in larvae of the brooding articulate brachiopod Argyrotheca cordata using immunocytochemistry combined with confocal laser scanning microscopy. Full grown larvae are three-lobed and show two pairs of bristle bundles. During larval development...

  8. Gaussian-like Spatial Priors for Articulated Tracking

    DEFF Research Database (Denmark)

    Hauberg, Søren; Sommer, Stefan Horst; Pedersen, Kim Steenstrup

    2010-01-01

    We present an analysis of the spatial covariance structure of an articulated     motion prior in which joint angles have a known covariance structure. From this,     a well-known, but often ignored, deficiency of the kinematic skeleton     representation becomes clear: spatial variance not only...

  9. Data-driven importance distributions for articulated tracking

    DEFF Research Database (Denmark)

    Hauberg, Søren; Pedersen, Kim Steenstrup

    2011-01-01

    We present two data-driven importance distributions for particle filterbased articulated tracking; one based on background subtraction, another on depth information. In order to keep the algorithms efficient, we represent human poses in terms of spatial joint positions. To ensure constant bone...

  10. Articulating social science in the wild of global natures?

    DEFF Research Database (Denmark)

    Blok, Anders

    2014-01-01

    Building on multisited ethnographic case studies, this paper seeks to contrastively compare the demonstration and articulation formats of two social science expert cultures—economics and anthropology—enrolled ‘in the wild’ of transnational environmental politics. How, the paper asks, do different...

  11. Frida Kahlo: Visual Articulations of Suffering and Loss.

    Science.gov (United States)

    Nixon, Lois LaCivita

    1996-01-01

    Illustrates the value of interdisciplinary approaches to patient care by exploring visual articulations of suffering as rendered by one artist. Makes general observations about the nature of humanities courses offered to medical students and depicts a visual portrayal of an illness story representing personal perspectives about patient suffering…

  12. Stuart Hall and the Theory and Practice of Articulation

    Science.gov (United States)

    Clarke, John

    2015-01-01

    In this article, I argue that the idea of articulation links three different dimensions of Stuart Hall's work: it is central to the work of cultural politics, to the work of hegemony and to his practice of embodied pedagogy. I claim that his approach to pedagogy entails the art of listening combined with the practice of theorising in the service…

  13. Air Conditioning and Refrigeration Program Articulation, 1981-1982.

    Science.gov (United States)

    Dallas County Community Coll. District, TX.

    Based on a survey of high school programs and courses in the Dallas County Community College District (DCCCD), this articulated program is designed to prepare students for entry-level employment in the air conditioning and refrigeration industry, including residential and commercial air conditioning and commercial refrigeration. The skills and…

  14. Frida Kahlo: Visual Articulations of Suffering and Loss.

    Science.gov (United States)

    Nixon, Lois LaCivita

    1996-01-01

    Illustrates the value of interdisciplinary approaches to patient care by exploring visual articulations of suffering as rendered by one artist. Makes general observations about the nature of humanities courses offered to medical students and depicts a visual portrayal of an illness story representing personal perspectives about patient suffering…

  15. [Malignant otitis externa with disfunction of the temporomandibular articulation].

    Science.gov (United States)

    Rojas Casanova, P; Pila Pérez, R; Dieguez Tejada, R; Pila Peláez, M

    1993-01-01

    Here we present a case of a female patient 70 years old stricken with diabetes mellitud 40 years of evolution with manifestations of malignant external otitis accompanied by disfunction of the temporomandibular articulation. Here we will show the clinical characteristics and the diagnosis in our patient likewise its treatment. We will expound the most important aspects of the entity at this present time.

  16. Stuart Hall and the Theory and Practice of Articulation

    Science.gov (United States)

    Clarke, John

    2015-01-01

    In this article, I argue that the idea of articulation links three different dimensions of Stuart Hall's work: it is central to the work of cultural politics, to the work of hegemony and to his practice of embodied pedagogy. I claim that his approach to pedagogy entails the art of listening combined with the practice of theorising in the service…

  17. Syllable reduction and articulation rates in Danish, Norwegian and Swedish

    NARCIS (Netherlands)

    Hilton, N.H.; Schüppert, Anja; Gooskens, C.S.

    2011-01-01

    This investigation compares articulation rates of phonological and phonetic syllables in Norwegian, Swedish and Danish to investigate differences in degrees of syllable deletion (reduction) among these three languages. For the investigation two sets of data are used: one consisting of recorded speec

  18. College Student Access: How Articulation Agreements Support Rural Students

    Science.gov (United States)

    Jaeger, Audrey J.; Dunstan, Stephany Brett; Dixon, Karrie Gibson

    2015-01-01

    Students from rural areas face additional burdens, such as affordability, academic preparation, and lack of college-going resources that make seeking, enrolling, and attending college more difficult. Community colleges offer hope to achieve a college degree for many rural students, and well-developed articulation agreements can be one way of…

  19. Articulated Multimedia Physics, Lesson 3, The Arithmetic of Scientific Notation.

    Science.gov (United States)

    New York Inst. of Tech., Old Westbury.

    As the third lesson of the Articulated Multimedia Physics Course, instructional materials are presented in this study guide. An introductory description is given for scientific notation methods. The subject content is provided in scrambled form, and the use of matrix transparencies is required for students to control their learning process.…

  20. Health Promotion Behavior of Chinese International Students in Korea Including Acculturation Factors: A Structural Equation Model.

    Science.gov (United States)

    Kim, Sun Jung; Yoo, Il Young

    2016-03-01

    The purpose of this study was to explain the health promotion behavior of Chinese international students in Korea using a structural equation model including acculturation factors. A survey using self-administered questionnaires was employed. Data were collected from 272 Chinese students who have resided in Korea for longer than 6 months. The data were analyzed using structural equation modeling. The p value of final model is .31. The fitness parameters of the final model such as goodness of fit index, adjusted goodness of fit index, normed fit index, non-normed fit index, and comparative fit index were more than .95. Root mean square of residual and root mean square error of approximation also met the criteria. Self-esteem, perceived health status, acculturative stress and acculturation level had direct effects on health promotion behavior of the participants and the model explained 30.0% of variance. The Chinese students in Korea with higher self-esteem, perceived health status, acculturation level, and lower acculturative stress reported higher health promotion behavior. The findings can be applied to develop health promotion strategies for this population. Copyright © 2016. Published by Elsevier B.V.

  1. Vocal tract articulation revisited: the case of the monk parakeet.

    Science.gov (United States)

    Ohms, Verena R; Beckers, Gabriël J L; ten Cate, Carel; Suthers, Roderick A

    2012-01-01

    Birdsong and human speech share many features with respect to vocal learning and development. However, the vocal production mechanisms have long been considered to be distinct. The vocal organ of songbirds is more complex than the human larynx, leading to the hypothesis that vocal variation in birdsong originates mainly at the sound source, while in humans it is primarily due to vocal tract filtering. However, several recent studies have indicated the importance of vocal tract articulators such as the beak and oropharyngeal-esophageal cavity. In contrast to most other bird groups, parrots have a prominent tongue, raising the possibility that tongue movements may also be of significant importance in vocal production in parrots, but evidence is rare and observations often anecdotal. In the current study we used X-ray cinematographic imaging of naturally vocalizing monk parakeets (Myiopsitta monachus) to assess which articulators are possibly involved in vocal tract filtering in this species. We observed prominent tongue height changes, beak opening movements and tracheal length changes, which suggests that all of these components play an important role in modulating vocal tract resonance. Moreover, the observation of tracheal shortening as a vocal articulator in live birds has to our knowledge not been described before. We also found strong positive correlations between beak opening and amplitude as well as changes in tongue height and amplitude in several types of vocalization. Our results suggest considerable differences between parrot and songbird vocal production while at the same time the parrot's vocal articulation might more closely resemble human speech production in the sense that both make extensive use of the tongue as a vocal articulator.

  2. To bend a coralline: effect of joint morphology on flexibility and stress amplification in an articulated calcified seaweed.

    Science.gov (United States)

    Martone, Patrick T; Denny, Mark W

    2008-11-01

    Previous studies have demonstrated that fleshy seaweeds resist wave-induced drag forces in part by being flexible. Flexibility allows fronds to 'go with the flow', reconfiguring into streamlined shapes and reducing frond area projected into flow. This paradigm extends even to articulated coralline algae, which produce calcified fronds that are flexible only because they have distinct joints (genicula). The evolution of flexibility through genicula was a major event that allowed articulated coralline algae to grow elaborate erect fronds in wave-exposed habitats. Here we describe the mechanics of genicula in the articulated coralline Calliarthron and demonstrate how segmentation affects bending performance and amplifies bending stresses within genicula. A numerical model successfully predicted deflections of articulated fronds by assuming genicula to be assemblages of cables connecting adjacent calcified segments (intergenicula). By varying the dimensions of genicula in the model, we predicted the optimal genicular morphology that maximizes flexibility while minimizing stress amplification. Morphological dimensions of genicula most prone to bending stresses (i.e. genicula near the base of fronds) match model predictions.

  3. Does a Socio-Ecological School Model Promote Resilience in Primary Schools?

    Science.gov (United States)

    Lee, Patricia C.; Stewart, Donald E.

    2013-01-01

    Background: This research investigates the extent to which the holistic, multistrategy "health-promoting school" (HPS) model using a resilience intervention can lead to improved resilience among students. Methods: A quasi-experimental design using a study cohort selected from 20 primary schools in Queensland, Australia was employed. Ten…

  4. Modeling the active sites of Co-promoted MoS2 particles by DFT

    DEFF Research Database (Denmark)

    Šaric, Manuel; Rossmeisl, Jan; Moses, Poul Georg

    2017-01-01

    The atomic-scale structure of the Co-promoted MoS2 catalyst (CoMoS), used for hydrodesulfurization and as a potential replacement for platinum in the acidic hydrogen evolution reaction has been analyzed by modeling its sites using density functional theory and applying thermochemical corrections...

  5. COMPASS: Collaborative Organizational Model to Promote Aligned Support Structures. Final Evaluation Report

    Science.gov (United States)

    Holliday, Lisa; Philp, Joel

    2015-01-01

    In 2010, Iredell-Statesville Schools was awarded an Investing in Innovation grant (i3) from the Office of Innovation and Improvement within the Federal Department of Education. Collaborative Organizational Model to Promote Aligned Support Structures (COMPASS) is a development grant that seeks to meet the needs of students with disabilities,…

  6. Implications of Articulating Machinery on Operator Line of Sight and Efficacy of Camera Based Proximity Detection Systems

    Directory of Open Access Journals (Sweden)

    Nicholas Schwabe

    2017-07-01

    Full Text Available The underground mining industry, and some above ground operations, rely on the use of heavy equipment that articulates to navigate corners in the tight confines of the tunnels. Poor line of sight (LOS has been identified as a problem for safe operation of this machinery. Proximity detection systems, such as a video system designed to provide a 360 degree view around the machine have been implemented to improve the available LOS for the operator. A four-camera system was modeled in a computer environment to assess LOS on a 3D cad model of a typical, articulated machine. When positioned without any articulation, the system is excellent at removing blind spots for a machine driving straight forward or backward in a straight tunnel. Further analysis reveals that when the machine articulates in a simulated corner section, some camera locations are no longer useful for improving LOS into the corner. In some cases, the operator has a superior view into the corner, when compared to the best available view from the camera. The work points to the need to integrate proximity detection systems at the design, build, and manufacture stage, and to consider proper policy and procedures that would address the gains and limits of the systems prior to implementation.

  7. The effect of skeletal pattern on determining articulator settings for prosthodontic rehabilitation: an in vivo study.

    LENUS (Irish Health Repository)

    Canning, Tom

    2011-01-01

    During extensive prosthodontic treatment, the use of an accurately adjusted articulator is recommended to simulate mandibular movements. This clinical study was undertaken to assess any possible effect of the underlying skeletal pattern on programming articulator settings.

  8. ECSCHOOL Model: A Case Study of Building Learning Support Community in ICT Promotion Project in Japan

    Directory of Open Access Journals (Sweden)

    Wei Zhou

    2010-06-01

    Full Text Available Due to concerns about the digital divide based on age, an ICT promotion project named “e-namokun” was started in Nagoya, Japan to support the Internet use by senior citizens. In the project, a learning support community system named ECSCHOOL (www.ecschool.org for senior citizens and ICT novices was developed to help them gain computer and Internet-related knowledge. The ECSCHOOL model has the following features: learning contents for different users, suitable communication and support tools, introduction of field research results, participation of ICT volunteers, an easy-to-use interface, and low development cost. The ECSCHOOL scheme is a new operational model for promoting e-learning in lifelong learning fields. This paper discusses the ECSCHOOL model, the system’s structure, its main functions, its learning content, and the formation of communities.

  9. Initiation-promotion model of tumor prevalence in mice from space radiation exposures.

    Science.gov (United States)

    Cucinotta, F A; Wilson, J W

    1995-08-01

    Exposures in space consist of low-level background components from galactic cosmic rays (GCR), occasional intense-energetic solar-particle events, periodic passes through geomagnetic-trapped radiation, and exposure from possible onboard nuclear-propulsion engines. Risk models for astronaut exposure from such diverse components and modalities must be developed to assure adequate protection in future NASA missions. The low-level background exposures (GCR), including relativistic heavy ions (HZE), will be the ultimate limiting factor for astronaut career exposure. We consider herein a two-mutation, initiation-promotion, radiation-carcinogenesis model in mice in which the initiation stage is represented by a linear kinetics model of cellular repair/misrepair, including the track-structure model for heavy ion action cross-sections. The model is validated by comparison with the harderian gland tumor experiments of Alpen et al. for various ion beams. We apply the initiation-promotion model to exposures from galactic cosmic rays, using models of the cosmic-ray environment and heavy ion transport, and consider the effects of the age of the mice prior to and after the exposure and of the length of time in space on predictions of relative risk. Our results indicate that biophysical models of age-dependent radiation hazard will provide a better understanding of GCR risk than models that rely strictly on estimates of the initial slopes of these radiations.

  10. Information System Success Model for Customer Relationship Management System in Health Promotion Centers

    Science.gov (United States)

    Choi, Wona; Rho, Mi Jung; Park, Jiyun; Kim, Kwang-Jum; Kwon, Young Dae

    2013-01-01

    Objectives Intensified competitiveness in the healthcare industry has increased the number of healthcare centers and propelled the introduction of customer relationship management (CRM) systems to meet diverse customer demands. This study aimed to develop the information system success model of the CRM system by investigating previously proposed indicators within the model. Methods The evaluation areas of the CRM system includes three areas: the system characteristics area (system quality, information quality, and service quality), the user area (perceived usefulness and user satisfaction), and the performance area (personal performance and organizational performance). Detailed evaluation criteria of the three areas were developed, and its validity was verified by a survey administered to CRM system users in 13 nationwide health promotion centers. The survey data were analyzed by the structural equation modeling method, and the results confirmed that the model is feasible. Results Information quality and service quality showed a statistically significant relationship with perceived usefulness and user satisfaction. Consequently, the perceived usefulness and user satisfaction had significant influence on individual performance as well as an indirect influence on organizational performance. Conclusions This study extends the research area on information success from general information systems to CRM systems in health promotion centers applying a previous information success model. This lays a foundation for evaluating health promotion center systems and provides a useful guide for successful implementation of hospital CRM systems. PMID:23882416

  11. Information system success model for customer relationship management system in health promotion centers.

    Science.gov (United States)

    Choi, Wona; Rho, Mi Jung; Park, Jiyun; Kim, Kwang-Jum; Kwon, Young Dae; Choi, In Young

    2013-06-01

    Intensified competitiveness in the healthcare industry has increased the number of healthcare centers and propelled the introduction of customer relationship management (CRM) systems to meet diverse customer demands. This study aimed to develop the information system success model of the CRM system by investigating previously proposed indicators within the model. THE EVALUATION AREAS OF THE CRM SYSTEM INCLUDES THREE AREAS: the system characteristics area (system quality, information quality, and service quality), the user area (perceived usefulness and user satisfaction), and the performance area (personal performance and organizational performance). Detailed evaluation criteria of the three areas were developed, and its validity was verified by a survey administered to CRM system users in 13 nationwide health promotion centers. The survey data were analyzed by the structural equation modeling method, and the results confirmed that the model is feasible. Information quality and service quality showed a statistically significant relationship with perceived usefulness and user satisfaction. Consequently, the perceived usefulness and user satisfaction had significant influence on individual performance as well as an indirect influence on organizational performance. This study extends the research area on information success from general information systems to CRM systems in health promotion centers applying a previous information success model. This lays a foundation for evaluating health promotion center systems and provides a useful guide for successful implementation of hospital CRM systems.

  12. A multilevel model of organizational health culture and the effectiveness of health promotion.

    Science.gov (United States)

    Lin, Yea-Wen; Lin, Yueh-Ysen

    2014-01-01

    Organizational health culture is a health-oriented core characteristic of the organization that is shared by all members. It is effective in regulating health-related behavior for employees and could therefore influence the effectiveness of health promotion efforts among organizations and employees. This study applied a multilevel analysis to verify the effects of organizational health culture on the organizational and individual effectiveness of health promotion. At the organizational level, we investigated the effect of organizational health culture on the organizational effectiveness of health promotion. At the individual level, we adopted a cross-level analysis to determine if organizational health culture affects employee effectiveness through the mediating effect of employee health behavior. The study setting consisted of the workplaces of various enterprises. We selected 54 enterprises in Taiwan and surveyed 20 full-time employees from each organization, for a total sample of 1011 employees. We developed the Organizational Health Culture Scale to measure employee perceptions and aggregated the individual data to formulate organization-level data. Organizational effectiveness of health promotion included four dimensions: planning effectiveness, production, outcome, and quality, which were measured by scale or objective indicators. The Health Promotion Lifestyle Scale was adopted for the measurement of health behavior. Employee effectiveness was measured subjectively in three dimensions: self-evaluated performance, altruism, and happiness. Following the calculation of descriptive statistics, hierarchical linear modeling (HLM) was used to test the multilevel hypotheses. Organizational health culture had a significant effect on the planning effectiveness (β = .356, p organizational health culture on three dimensions of employee effectiveness were completely mediated by health behavior. The construct connections established in this multilevel model will help in

  13. Note sur les articulations de la linéarité phrastique

    OpenAIRE

    Rostislav Kocourek

    2012-01-01

    The term structuring is here used as an equivalent of various meanings of terms sentence perspective or sentence articulation found in terms Functional Sentence Perspective (FSP), or Actual Sentence Articulation, or in phrases used in the present paper as l’articulation ordinaire or l’articulation poétique.The introductory sections of the paper deal with the typological and diachronic aspects of word order, and with the proposal to use permutation as a promising procedure preparing to obtain ...

  14. MyReDiary: Co-Designing for Collaborative Articulation in Physical Rehabilitation

    DEFF Research Database (Denmark)

    Bagalkot, Naveen L.; Sokoler, Tomas

    2011-01-01

    In this paper we present our exploration of co-designing for supporting a collaborative articulation of rehabilitation process. Based on our reading of key CSCW literature, we describe three facets of a collaboratively articulated rehab process: Interdependence, Distributed Process, and Interoper......In this paper we present our exploration of co-designing for supporting a collaborative articulation of rehabilitation process. Based on our reading of key CSCW literature, we describe three facets of a collaboratively articulated rehab process: Interdependence, Distributed Process...

  15. Gender recognition from unconstrained and articulated human body.

    Science.gov (United States)

    Wu, Qin; Guo, Guodong

    2014-01-01

    Gender recognition has many useful applications, ranging from business intelligence to image search and social activity analysis. Traditional research on gender recognition focuses on face images in a constrained environment. This paper proposes a method for gender recognition in articulated human body images acquired from an unconstrained environment in the real world. A systematic study of some critical issues in body-based gender recognition, such as which body parts are informative, how many body parts are needed to combine together, and what representations are good for articulated body-based gender recognition, is also presented. This paper also pursues data fusion schemes and efficient feature dimensionality reduction based on the partial least squares estimation. Extensive experiments are performed on two unconstrained databases which have not been explored before for gender recognition.

  16. Attitude Dynamics and Control of Solar Sails with Articulated Vanes

    Science.gov (United States)

    Mettler, Edward; Acikmese, A. Behcet; Ploen, Scott R.

    2005-01-01

    In this paper we develop a robust nonlinear algorithm for the attitude control of a solar sailcraft with M single degree-of-freedom articulated control vanes. A general attitude controller that tracks an admissible trajectory while rejecting disturbances such as torques due to center-of-mass to center-of-pressure offsets is applied to this problem. We then describe a methodology based on nonlinear programming to allocate the required control torques among the control vanes. A simplified allocation strategy is then applied to a solar sail with four articulated control vanes, and simulation results are given. The performance of the control algorithm and possible limitations of vane-only control are then discussed.

  17. Design and Construction of Passively Articulated Ornithopter Wings

    Science.gov (United States)

    Mastro, Alexander Timothy

    Birds, bats, and insects are able to fly efficiently and execute impressive in-flight, landing, and takeoff maneuvers with apparent ease through actuation of their highly articulated wings. This contrasts the approach used to enable the flight of comparatively simple man-made rotary and fixed wing aircraft. The complex aerodynamics underlying flapping-based flight pose an everpresent challenge to scientists hoping to reveal the secrets of animal flight. Despite this, interest in engineering aircraft on the bird and insect scale is higher than ever. Herein, I present my attempt to design and construct bioinspired passively articulated ornithopter wings. Two different hinge-based joint design concepts are investigated across several design iterations. The advantages and disadvantages of each implementation are discussed. Finally, the necessary instrumentation to analyze the performance of the wings is designed and fabricated, followed by testing of the wings.

  18. The calculation of robot dynamics using articulated-body inertias

    Science.gov (United States)

    Featherstone, R.

    1983-05-01

    This paper describes a new method for calculating the acceleration of a robot in response to given actuator forces. The method is applicable to open-loop kinematic chains containing revolute and prismatic joints. The algorithm is based on recursive formulas involving quantities called articulated-body inertias, which represent the inertia properties of collections of rigid bodies connected together by joints allowing constrained relative motion between the bodies. A new, matrix-based notation is introduced to represent articulated-body inertias and other spatial quantities. This notation is used to develop the algorithm, and results in a compact representation of the equations. The new algorithm has a computational requirement that varies linearly with the number of joints, and its efficiency is compared with other published algorithms.

  19. Facilitated Articulation of Implicit Knowledge in Textile Design

    DEFF Research Database (Denmark)

    Bang, Anne Louise

    2009-01-01

    This is a report from an ongoing research project and as such it is work in progress. The paper proposes an exploratory approach in order to enable end-users to contribute with their experiences of emotional values of fabrics in use. It is suggested that the textile designer with her repertoire...... of (experiential, implicit and tacit) textile design knowledge should facilitate the articulation process. The paper specifically draws on a series of workshops conducted within the collaborating company inviting all employees to participate. The series of workshops were based on a game-like setting and introduced...... an emergent framework for accessing implicit knowledge in textile design. The framework is based on the distance to the fabric. Present at each workshop were materials, chairs and images as initiators for articulation. In each workshop rules for playing and gaming materials were introduced by the author...

  20. Policy development and implementation in health promotion--from theory to practice: the ADEPT model.

    Science.gov (United States)

    Rütten, Alfred; Gelius, Peter; Abu-Omar, Karim

    2011-09-01

    There is a growing interest among health promotion researchers to better understand and influence the policy process. However, at this point in time, theoretical concepts enabling researchers to do so are still rare and underused, suggesting a need for new, easy-to-use concepts to explain successes or failures of health promotion policies. This article presents the ADEPT (Analysis of Determinants of Policy Impact) approach, which aims to explain and influence policy development and policy impact implementation with four determinants: goals, obligations, resources and opportunities. ADEPT provides a detailed operationalization for both quantitative and qualitative use. An empirical test of the ADEPT model using a quantitative survey of 719 policy-makers from four health promotion policy fields and six European nations indicated that both policy outputs and policy outcomes are influenced by the four determinants. The approach has, in the meantime, been successfully utilized to analyze and initiate policy development in a number of health promotion projects. Despite a number of limitations, ADEPT provides an easy-to-use, theory-based and parsimonious tool for understanding and influencing policy processes in health promotion. Moreover, as it identifies potential 'levers of influence' and can easily be connected to existing methods of community development or capacity building, it is a particularly powerful tool for policy development.

  1. Gender Recognition from Unconstrained and Articulated Human Body

    OpenAIRE

    Qin Wu; Guodong Guo

    2014-01-01

    Gender recognition has many useful applications, ranging from business intelligence to image search and social activity analysis. Traditional research on gender recognition focuses on face images in a constrained environment. This paper proposes a method for gender recognition in articulated human body images acquired from an unconstrained environment in the real world. A systematic study of some critical issues in body-based gender recognition, such as which body parts are informative, ho...

  2. Method for optimization of statically determined articulated structures

    OpenAIRE

    Parras Galán, L.; Montes Tubío, M.; García Guzmán, A.; Entrenas Angulo, J.A.; de Dios Palomares, R.

    1985-01-01

    An algorithm of mathematical programmation for the optimum disign of iso-static articulate structures has been developed. The characteristics of the proposed algorithm are: a) It not requires that the objective function or the restriction equations be derivable. b) They use unidimensional methods of unidimensional optimization to pass over from a given solution to a better one. c) To introduce contingent procedures to obtain Information which leads to a better solution. Those characteristics ...

  3. Functional Organization of Human Sensorimotor Cortex for Speech Articulation

    Science.gov (United States)

    Bouchard, Kristofer E.; Mesgarani, Nima; Johnson, Keith; Chang, Edward F.

    2013-01-01

    Speaking is one of the most complex actions we perform, yet nearly all of us learn to do it effortlessly. Production of fluent speech requires the precise, coordinated movement of multiple articulators (e.g., lips, jaw, tongue, larynx) over rapid time scales. Here, we used high-resolution, multi-electrode cortical recordings during the production of consonant-vowel syllables to determine the organization of speech sensorimotor cortex in humans. We found speech articulator representations that were somatotopically arranged on ventral pre- and post-central gyri and partially overlapping at individual electrodes. These representations were temporally coordinated as sequences during syllable production. Spatial patterns of cortical activity revealed an emergent, population-level representation, which was organized by phonetic features. Over tens of milliseconds, the spatial patterns transitioned between distinct representations for different consonants and vowels. These results reveal the dynamic organization of speech sensorimotor cortex during the generation of multi-articulator movements underlying our ability to speak. PMID:23426266

  4. Oral approach-avoidance: affective consequences of muscular articulation dynamics.

    Science.gov (United States)

    Topolinski, Sascha; Maschmann, Ira Theresa; Pecher, Diane; Winkielman, Piotr

    2014-06-01

    Can mouth movements shape attitudes? When people articulate different consonants (e.g., B or K) they press the tongue and the lips against various spots in the mouth. This allows for construction of words that feature systematic wanderings of consonantal stricture spots either from the front to the rear (inward; e.g., BENOKA) or from the rear to the front (outward; e.g., KENOBA) of the mouth. These wanderings of muscular strictures resemble the oral kinematics during either deglution (swallowing-like, inward movement) or expectoration (spitting-like, outward movement). Thus, we predicted that the articulation of inward and outward words induces motivational states associated with deglutition and expectoration--namely, approach and avoidance--which was tested in 9 experiments (total N = 822). Inward words were preferred over outward words, being labeled as nonsense words (Experiments 1, 4, 5, 6, and 9), company names (Experiment 2), or person names (Experiments 3, 7, and 8), with control words falling in between (Experiment 5). As a social-behavioral consequence, ostensible chat partners were more often chosen to interact with when having inward compared to outward names (Experiment 7). The effect was found in German-speaking (Experiments 1-5) and English-speaking (Experiment 6) samples, and it occurred even under silent reading (all experiments) and for negatively labeled targets (names of villains; Experiment 8). Showing articulation simulations as being the causal undercurrent, this effect was absent in aphasia patients who lacked covert subvocalizations (Experiment 9).

  5. Recognizing articulated objects using a region-based invariant transform.

    Science.gov (United States)

    Weiss, Isaac; Ray, Manjit

    2005-10-01

    In this paper, we present a new method for representing and recognizing objects, based on invariants of the object's regions. We apply the method to articulated objects in low-resolution, noisy range images. Articulated objects such as a back-hoe can have many degrees of freedom, in addition to the unknown variables of viewpoint. Recognizing such an object in an image can involve a search in a high-dimensional space that involves all these unknown variables. Here, we use invariance to reduce this search space to a manageable size. The low resolution of our range images makes it hard to use common features such as edges to find invariants. We have thus developed a new "featureless" method that does not depend on feature detection. Instead of local features, we deal with whole regions of the object. We define a "transform" that converts the image into an invariant representation on a grid, based on invariant descriptors of entire regions centered around the grid points. We use these region-based invariants for indexing and recognition. While the focus here is on articulation, the method can be easily applied to other problems such as the occlusion of fixed objects.

  6. Dealing with Phrase Level Co-Articulation (PLC) in speech recognition: a first approach

    NARCIS (Netherlands)

    Ordelman, Roeland J.F.; van Hessen, Adrianus J.; van Leeuwen, David A.; Robinson, Tony; Renals, Steve

    1999-01-01

    Whereas nowadays within-word co-articulation effects are usually sufficiently dealt with in automatic speech recognition, this is not always the case with phrase level co-articulation effects (PLC). This paper describes a first approach in dealing with phrase level co-articulation by applying these

  7. Use of low power EM radar sensors for speech articulator measurements

    Energy Technology Data Exchange (ETDEWEB)

    Holzrichter, J.F.; Burnett, G.C.

    1997-05-14

    Very low power electromagnetic (EM) wave sensors are being used to measure speech articulator motions such as the vocal fold oscillations, jaw, tongue, and the soft palate. Data on vocal fold motions, that correlate well with established laboratory techniques, as well as data on the jaw, tongue, and soft palate are shown. The vocal fold measurements together with a volume air flow model are being used to perform pitch synchronous estimates of the voiced transfer functions using ARMA (autoregressive moving average) techniques. 6 refs., 5 figs.

  8. The Health Equity Promotion Model: Reconceptualization of Lesbian, Gay, Bisexual, and Transgender (LGBT) Health Disparities

    Science.gov (United States)

    Fredriksen-Goldsen, Karen I.; Simoni, Jane M.; Kim, Hyun-Jun; Lehavot, Keren; Walters, Karina L.; Yang, Joyce; Hoy-Ellis, Charles P.

    2015-01-01

    National health initiatives emphasize the importance of eliminating health disparities among historically disadvantaged populations. Yet, few studies have examined the range of health outcomes among lesbian, gay, bisexual, and transgender (LGBT) people. To stimulate more inclusive research in the area, we present the Health Equity Promotion Model—a framework oriented toward LGBT people reaching their full mental and physical health potential that considers both positive and adverse health-related circumstances. The model highlights (a) heterogeneity and intersectionality within LGBT communities; (b) the influence of structural and environmental context; and (c) both health-promoting and adverse pathways that encompass behavioral, social, psychological, and biological processes. It also expands upon earlier conceptualizations of sexual minority health by integrating a life course development perspective within the health-promotion model. By explicating the important role of agency and resilience as well as the deleterious effect of social structures on health outcomes, it supports policy and social justice to advance health and well-being in these communities. Important directions for future research as well as implications for health-promotion interventions and policies are offered. PMID:25545433

  9. Model Development for Health Promotion in the Elderly Participating in Communities

    Directory of Open Access Journals (Sweden)

    Supat Jampawai

    2011-01-01

    Full Text Available Problem statement: The problem of the research derives from a lack of research study to develop the suitable model for health promotion in the elderly and examine factors concerning the health promotion in the elderly. This research aimed to study and develop suitable health promotion model for elderly participating in communities and examine factors related to the health promotion of the elderly. Approach: The samples were 654 older people. This study was participatory action research including many stages which were situation analysis, action and assessment. The explored location was the area of Nonsa-ad Sub-District, Nong Ruea District, Khon Kaen Province. Results: The results of the study led to the process of health promotion for the elderly participating in the communities in the action stage including the participation of the communities, local administrative organizations and government agencies consisting of health service centers and department of social development and human security to drive the thinking of the elderly and push it into real practice. The activities for the health promotion were health check-up, home visit of volunteers and public health staff, exercise, having suitable food, stress management, adequate sleep, avoidance to alcohol, steroids, smoking, accidents and resistance to hard work. After a year of these activities, the health condition of the aged people was better while several health problems decreased such as the rate of sickness, risk group of chronic diseases, join and muscular pain. Besides, diabetes and blood pressure were at the same level. The patients with diabetes and blood pressure were able to better control glucose level and blood pressure at the safe rate without any complications. The whole quality of life of the elderly on physical and mental health, daily routine, society and finance were also increased by 63.15%. Furthermore, sex and age were significantly related to the health promotion for

  10. Role Modeling Attitudes, Physical Activity and Fitness Promoting Behaviors of Prospective Physical Education Specialists and Non-Specialists.

    Science.gov (United States)

    Cardinal, Bradley J.; Cardinal, Marita K.

    2002-01-01

    Compared the role modeling attitudes and physical activity and fitness promoting behaviors of undergraduate students majoring in physical education and in elementary education. Student teacher surveys indicated that physical education majors had more positive attitudes toward role modeling physical activity and fitness promoting behaviors and…

  11. Incorporation of Active Elements into the Articulated Total Body Model.

    Science.gov (United States)

    1985-06-30

    one muscle/harness system representing the biceps brachii and the brachialis. The results indicated that the force velocity effects produced the...Production by the Biceps during Eccentric Motion ... .... .53 vii LIST OF TABLES Table Page - 1 Specifications on Elbow Musculature...z disks does not allow appreciable movement. The tendinous parts of the muscle fiber are located near the origin and insertion of the fiber and thus

  12. Limits and articulations between modalities and meditative as markers of utterance responsibility in academic text

    Directory of Open Access Journals (Sweden)

    Jorge Luis Queiroz Carvalho

    2014-07-01

    Full Text Available In this work we aim to identify and describe the markers of utterance responsibility in academic texts through modality and mediative. The theoretical and methodological approach we follow is based on textual analysis of discourses postulates according to Adam (2011. Our theoretical background is also based on Rabatel (2009 studies on the utterance responsibility; Campos (2004 and Castilho & Castilho (2002 on the category of modalities, Guentchèva (1994 regarding the meditative category, and Neves (2012, which promotes a discussion that articulates both categories. The analysis showed that speakers-utterers (S1/U1 base their points of view on the second utterer's points of view (U2. We also observed that S1/U1 expressed different degrees of engagement in relation to the information reported, assuming or imputing the utterance responsibility

  13. Waif goodbye! Average-size female models promote positive body image and appeal to consumers.

    Science.gov (United States)

    Diedrichs, Phillippa C; Lee, Christina

    2011-10-01

    Despite consensus that exposure to media images of thin fashion models is associated with poor body image and disordered eating behaviours, few attempts have been made to enact change in the media. This study sought to investigate an effective alternative to current media imagery, by exploring the advertising effectiveness of average-size female fashion models, and their impact on the body image of both women and men. A sample of 171 women and 120 men were assigned to one of three advertisement conditions: no models, thin models and average-size models. Women and men rated average-size models as equally effective in advertisements as thin and no models. For women with average and high levels of internalisation of cultural beauty ideals, exposure to average-size female models was associated with a significantly more positive body image state in comparison to exposure to thin models and no models. For men reporting high levels of internalisation, exposure to average-size models was also associated with a more positive body image state in comparison to viewing thin models. These findings suggest that average-size female models can promote positive body image and appeal to consumers.

  14. Allopregnanolone promotes regeneration and reduces β-amyloid burden in a preclinical model of Alzheimer's disease.

    Directory of Open Access Journals (Sweden)

    Shuhua Chen

    Full Text Available Previously, we demonstrated that allopregnanolone (APα promoted proliferation of rodent and human neural progenitor cells in vitro. Further, we demonstrated that APα promoted neurogenesis in the hippocampal subgranular zone (SGZ and reversed learning and memory deficits in the male triple transgenic mouse model of Alzheimer's (3xTgAD. In the current study, we determined the efficacy of APα to promote the survival of newly generated neural cells while simultaneously reducing Alzheimer's disease (AD pathology in the 3xTgAD male mouse model. Comparative analyses between three different APα treatment regimens indicated that APα administered 1/week for 6 months was maximally efficacious for simultaneous promotion of neurogenesis and survival of newly generated cells and reduction of AD pathology. We further investigated the efficacy of APα to impact Aβ burden. Treatment was initiated either prior to or post intraneuronal Aβ accumulation. Results indicated that APα administered 1/week for 6 months significantly increased survival of newly generated neurons and simultaneously reduced Aβ pathology with greatest efficacy in the pre-pathology treatment group. APα significantly reduced Aβ generation in hippocampus, cortex, and amygdala, which was paralleled by decreased expression of Aβ-binding-alcohol-dehydrogenase. In addition, APα significantly reduced microglia activation as indicated by reduced expression of OX42 while increasing CNPase, an oligodendrocyte myelin marker. Mechanistic analyses indicated that pre-pathology treatment with APα increased expression of liver-X-receptor, pregnane-X-receptor, and 3-hydroxy-3-methyl-glutaryl-CoA-reductase (HMG-CoA-R, three proteins that regulate cholesterol homeostasis and clearance from brain. Together these findings provide preclinical evidence for the optimal treatment regimen of APα to achieve efficacy as a disease modifying therapeutic to promote regeneration while simultaneously decreasing

  15. Engaging youth in rural Uganda in articulating health priorities through Photovoice.

    Science.gov (United States)

    Esau, Daniel; Ho, Pak To; Blair, Geoffrey K; Duffy, Damian; O'Hara, Nathan N; Kapoor, Videsh; Ajiko, Margaret

    2016-04-07

    Youth living in rural Uganda represent over 20% of the country's population. Despite the size of this demographic, there is a paucity of data on their health priorities. Engaging people in understanding their own health status has been proven to be an effective mechanism for health promotion. The objective of this study was to use Photovoice, a community-based, participatory action research methodology, to understand the current health priorities of youth living in rural Uganda. Thirty-two students between the ages of 13 and 17 were recruited from four schools within the region of Soroti, Uganda. Participants were given a disposable camera and were asked to photograph situations that contributed or detracted from their health status. The cameras were then returned to the investigators and each photo taken by the participant was reviewed with the investigators during a semi-structured interview. Codes were applied to the photographs and organized into overarching themes. Each participant chose one to two photos that were most representative of their health priorities for a secondary analysis. Participants provided 499 photos that met the eligibility criteria. The most common themes presented in the photographs were 'hygiene' (n= 73, 12.4%), 'nutrition' (n= 69, 11.7%), and 'cleanliness' (n= 48, 8%). 'Hygiene' (n= 6, 14.6%) and 'exercise' (n= 6, 14.6%) were the most common priorities articulated in the representative photographs. Photovoice proved to be an effective method to assess and express the health concerns of youth in rural Uganda. Study participants were able to articulate their health concerns and priorities through photographs and reflect on opportunities for health promotion through subsequent interviews. © The Author(s) 2015.

  16. Study on Roll Instability Mechanism and Stability Index of Articulated Steering Vehicles

    Directory of Open Access Journals (Sweden)

    Xuefei Li

    2016-01-01

    Full Text Available This study examines the roll instability mechanism and stability index of articulated steering vehicles (ASVs by taking wheel loaders as the research object. A seven-degree-of-freedom nonlinear dynamics model of the ASVs is built on the basis of multibody dynamics. A physical prototype model of an ASV is designed and manufactured to validate the dynamic model. Test results reasonably agree with the simulation results, which indicates that the established dynamic model can reasonably describe ASV movements. Detailed analysis of the rollover stability of the wheel loader is performed with the use of the established dynamic model. Analysis results show that rollover will occur when the roll angular velocity exceeds a critical threshold, which is affected by lateral acceleration and slope angle. On this basis, a dynamic stability index applicable to the ASVs is presented.

  17. Statistical mechanical model of coupled transcription from multiple promoters due to transcription factor titration

    Science.gov (United States)

    Rydenfelt, Mattias; Cox, Robert Sidney, III; Garcia, Hernan; Phillips, Rob

    2014-01-01

    Transcription factors (TFs) with regulatory action at multiple promoter targets is the rule rather than the exception, with examples ranging from the cAMP receptor protein (CRP) in E. coli that regulates hundreds of different genes simultaneously to situations involving multiple copies of the same gene, such as plasmids, retrotransposons, or highly replicated viral DNA. When the number of TFs heavily exceeds the number of binding sites, TF binding to each promoter can be regarded as independent. However, when the number of TF molecules is comparable to the number of binding sites, TF titration will result in correlation (“promoter entanglement”) between transcription of different genes. We develop a statistical mechanical model which takes the TF titration effect into account and use it to predict both the level of gene expression for a general set of promoters and the resulting correlation in transcription rates of different genes. Our results show that the TF titration effect could be important for understanding gene expression in many regulatory settings.

  18. Introduction of MAN Lion’s City Conceptual Articulated Bus%德国曼恩客车系列愈加丰富

    Institute of Scientific and Technical Information of China (English)

    云清文

    2016-01-01

    During IAA 2016, German based MAN demonstrated total of ten models of various buses including city-bus, city-to-city bus and long-distance bus, etc. Among all these models, the most innovative highlight is the model of MAN Lion’s City Conceptual Articulated bus, as well as the re-charging technology associated to it.

  19. T-tubule disruption promotes calcium alternans in failing ventricular myocytes: mechanistic insights from computational modeling.

    Science.gov (United States)

    Nivala, Michael; Song, Zhen; Weiss, James N; Qu, Zhilin

    2015-02-01

    In heart failure (HF), T-tubule (TT) disruption contributes to dyssynchronous calcium (Ca) release and impaired contraction, but its role in arrhythmogenesis remains unclear. In this study, we investigate the effects of TT disruption and other HF remodeling factors on Ca alternans in ventricular myocytes using computer modeling. A ventricular myocyte model with detailed spatiotemporal Ca cycling modeled by a coupled Ca release unit (CRU) network was used, in which the L-type Ca channels and the ryanodine receptor (RyR) channels were simulated by random Markov transitions. TT disruption, which removes the L-type Ca channels from the associated CRUs, results in "orphaned" RyR clusters and thus provides increased opportunity for spark-induced Ca sparks to occur. This effect combined with other HF remodeling factors promoted alternans by two distinct mechanisms: 1) for normal sarco-endoplasmic reticulum Ca ATPase (SERCA) activity, alternans was caused by both CRU refractoriness and coupling. The increased opportunity for spark-induced sparks by TT disruption combined with the enhanced CRU coupling by Ca elevation in the presence or absence of increased RyR leakiness facilitated spark synchronization on alternate beats to promote Ca alternans; 2) for down-regulated SERCA, alternans was caused by the sarcoplasmic reticulum (SR) Ca load-dependent mechanism, independent of CRU refractoriness. TT disruption and increased RyR leakiness shifted and steepened the SR Ca release-load relationship, which combines with down-regulated SERCA to promote Ca alternans. In conclusion, the mechanisms of Ca alternans for normal and down-regulated SERCA are different, and TT disruption promotes Ca alternans by both mechanisms, which may contribute to alternans at different stages of HF.

  20. Woman and language in darkest Africa: The quest for articulation in two postcolonial novels

    Directory of Open Access Journals (Sweden)

    A. Brink

    1992-05-01

    Full Text Available The paper focuses on issues raised by Conrad’s Heart of Darkness and on ways in which two recent novels, The Expedition to the Baobab Tree (Stockenstrdni and The Whales in Lake Tanganyika (Hagerfors employ the same model of the journey of exploration in order to break down phallo- and eurocentric concepts of language in an attempt to arrive at a new articulation of Africa. In Heart of Darkness Marlow crosses the limits of language in his confrontation with the Other (Kurtz, and Africa, both of which have a female dimension and has to invent a ‘new’ language, post facto, to explain his discovery to the Woman who awaits him at the other end. In the Stockenstrdm text, the narrator and central personage is already female, but she is illiterate; and in order to articulate her body, in which her journey is subsumed, an implied narrator may have to narrate on her behalf, in a language which first has to liberate itself from the processes of bondage and appropriation to which the slave woman has been subjected all her life. In The Whales in Lake Tanganyika an interiext arises from the dialogue of this narrative with H.M. Stanley's historical journal; and this projects the diarist Shaw as the deconstructor of male and European dichotomies. Shedding conventional langitage, linearity and 'reality’, his diary becomes the translation of an inaccessible ‘new’ language which is the only way in which Spivak’s 'subaltern’ can attain speech to articulate the femininity implicit in Africa.

  1. Articulating addiction in alcohol and other drug policy: A multiverse of habits.

    Science.gov (United States)

    Fraser, Suzanne

    2016-05-01

    Concepts of addiction differ across time and place. This article is based on an international research project currently exploring this variation and change in concepts of addiction, in particular in the field of alcohol and other drug (AOD) use. Taking AOD policy in Australia and Canada as its empirical focus, and in-depth interviews with policy makers, service providers and advocates in each country as its key method (N=60), the article compares the addiction concepts articulated by professionals working in each setting. Drawing on Bruno Latour's theoretical work on the body and his proposal for a better science based on the 'articulation of differences', it explores the accounts of addiction offered across the Australian and Canadian project sites, identifying a shared dynamic in all: the juggling of difference and unity in discussions of the nature of addiction, its composite parts and how best to respond to it. The article maps two simultaneous trajectories in the data - one moving towards difference in participants' insistence on the multitude and diversity of factors that make up addiction problems and solutions, and the other towards unity in their tendency to return to narrow disease models of addiction in uncomfortable, sometimes dissonant, strategic choices. As I will argue, the AOD professionals interviewed for my project operate in two modes treated as distinct in Latour's proposal: in turning to reifying disease labels of addiction they take for granted, and work within, a 'universe of essences', but in articulating the multiplicity and diversity of addiction, they grope towards a vision of a 'multiverse of habits'. The article concludes by addressing this tension directly, scrutinising its practical implications for the development of policy and delivery of services in the future, asking how new thinking, and therefore new opportunities, might be allowed to emerge.

  2. Evaluation of the hydrodynamic behaviour of turbulence promoters in parallel plate electrochemical reactors by means of the dispersion model

    Energy Technology Data Exchange (ETDEWEB)

    Colli, A.N. [Programa de Electroquimica Aplicada e Ingenieria Electroquimica (PRELINE), Facultad de Ingenieria Quimica, Universidad Nacional del Litoral, Santiago del Estero 2829, S3000AOM Santa Fe (Argentina); Bisang, J.M., E-mail: jbisang@fiq.unl.edu.ar [Programa de Electroquimica Aplicada e Ingenieria Electroquimica (PRELINE), Facultad de Ingenieria Quimica, Universidad Nacional del Litoral, Santiago del Estero 2829, S3000AOM Santa Fe (Argentina)

    2011-08-30

    Highlights: {center_dot} The type of turbulence promoters has a strong influence on the hydrodynamics. {center_dot} The dispersion model is appropriate for expanded plastic turbulence promoters. {center_dot} The dispersion model is appropriate for glass beads turbulence promoters. - Abstract: The hydrodynamic behaviour of electrochemical reactors with parallel plate electrodes is experimentally studied using the stimulus-response method either with an empty reactor or with different turbulence promoters. Theoretical results which are in accordance with the analytical and numerical resolution of the dispersion model for a closed system are compared with the classical relationships of the normalized outlet concentration for open systems and the validity range of the equations is discussed. The experimental results were well correlated with the dispersion model using glass beads or expanded plastic meshes as turbulence promoters, which have shown the most advantageous performance. The Peclet number was higher than 63. The dispersion coefficient was found to increase linearly with flow velocity in these cases.

  3. Sideslip estimation for articulated heavy vehicles at the limits of adhesion

    Science.gov (United States)

    Morrison, Graeme; Cebon, David

    2016-11-01

    Various active safety systems proposed for articulated heavy goods vehicles (HGVs) require an accurate estimate of vehicle sideslip angle. However in contrast to passenger cars, there has been minimal published research on sideslip estimation for articulated HGVs. State-of-the-art observers, which rely on linear vehicle models, perform poorly when manoeuvring near the limits of tyre adhesion. This paper investigates three nonlinear Kalman filters (KFs) for estimating the tractor sideslip angle of a tractor-semitrailer. These are compared to the current state-of-the-art, through computer simulations and vehicle test data. An unscented KF using a 5 degrees-of-freedom single-track vehicle model with linear adaptive tyres is found to substantially outperform the state-of-the-art linear KF across a range of test manoeuvres on different surfaces, both at constant speed and during emergency braking. Robustness of the observer to parameter uncertainty is also demonstrated. Data supporting this research can be accessed at http://dx.doi.org/10.17863/CAM.1234

  4. Acquisition of vowel articulation in childhood investigated by acoustic-to-articulatory inversion.

    Science.gov (United States)

    Oohashi, Hiroki; Watanabe, Hama; Taga, Gentaro

    2017-02-01

    While the acoustical features of speech sounds in children have been extensively studied, limited information is available as to their articulation during speech production. Instead of directly measuring articulatory movements, this study used an acoustic-to-articulatory inversion model with scalable vocal tract size to estimate developmental changes in articulatory state during vowel production. Using a pseudo-inverse Jacobian matrix of a model mapping seven articulatory parameters to acoustic ones, the formant frequencies of each vowel produced by three Japanese children over time at ages between 6 and 60 months were transformed into articulatory parameters. We conducted the discriminant analysis to reveal differences in articulatory states for production of each vowel. The analysis suggested that development of vowel production went through gradual functionalization of articulatory parameters. At 6-9 months, the coordination of position of tongue body and lip aperture forms three vowels: front, back, and central. At 10-17 months, recruitments of jaw and tongue apex enable differentiation of these three vowels into five. At 18 months and older, recruitment of tongue shape produces more distinct vowels specific to Japanese. These results suggest that the jaw and tongue apex contributed to speech production by young children regardless of kinds of vowel. Moreover, initial articulatory states for each vowel could be distinguished by the manner of coordination between lip and tongue, and these initial states are differentiated and refined into articulations adjusted to the native language over the course of development. Copyright © 2017 Elsevier Inc. All rights reserved.

  5. An improvement in rollover detection of articulated vehicles using the grey system theory

    Science.gov (United States)

    Chou, Tao; Chu, Tzyy-Wen

    2014-05-01

    A Rollover Index combined with the grey system theory, called a Grey Rollover Index (GRI), is proposed to assess the rollover threat for articulated vehicles with a tractor-semitrailer combination. This index can predict future trends of vehicle dynamics based on current vehicle motion; thus, it is suitable for vehicle-rollover detection. Two difficulties are encountered when applying the GRI for rollover detection. The first difficulty is effectively predicting the rollover threat of the vehicles, and the second difficulty is achieving a definite definition of the real rollover timing of a vehicle. The following methods are used to resolve these problems. First, a nonlinear mathematical model is constructed to accurately describe the vehicle dynamics of articulated vehicles. This model is combined with the GRI to predict rollover propensity. Finally, TruckSim™ software is used to determine the real rollover timing and facilitate the accurate supply of information to the rollover detection system through the GRI. This index is used to verify the simulation based on the common manoeuvres that cause rollover accidents to reduce the occurrence of false signals and effectively increase the efficiency of the rollover detection system.

  6. DISORDERS OF THE SOUND ARTICULATION IN PRETERM CHILDREN

    Directory of Open Access Journals (Sweden)

    Vesela MILANKOV

    2009-11-01

    Full Text Available Speech and language development is a good indicator of child’s cognitive development. The risk factors influencing development and functioning of prematurely born children are multiple. In addition to articulation disorder, there are motoric, conginitive and social aspects of delayed development. Premature babies are born before they physically ready to leave the womb. However, most babies born after about 26 weeks of gestational age have chances for survival, but they are at a greater risk of medical complications, since the earlier children are born, the less developed their organs are. Aim: To demonstrate basic parameters, establish differences, determine characteristics of disorder of sound articulation in fullterm and preterm children. Methodology: Research was conducted at the Clinics of Child’s Habilitation and Rehabilitation in Novi Sad. The prospective research study was carried out comprising 61 children with mean age of 4 years. The study inclusion criteria were gestational age and birth weight. Regarding these parameters, the children without major neurlologic or system disabilities were included, and they were Serbian speaking. The sample comprised 31 children with GS≥38 weeks and body weight of ≥3000 g, while the preterm group comprised 30 children with GS≤32 weeks and body weight of ≤1500 g. Results of the study indicate to a difference between fullterm children and preterm children with regard to articulation disorders, of which the statistically significant was a sound distortion. The overall sample showed that the substitution with distortion was most frequent disorder, while the interdental sigmatism was the most represented one. Conclusion: The obtained results lead to conclusion that preterm children, being a high-risk group, need to be followed up by age two, and provided timely proffesional help at pre-school age, since numerous adverse factors affect their overall development.

  7. Effect of health belief model and health promotion model on breast cancer early diagnosis behavior: a systematic review.

    Science.gov (United States)

    Ersin, Fatma; Bahar, Zuhal

    2011-01-01

    Breast cancer is an important public health problem on the grounds that it is frequently seen and it is a fatal disease. The objective of this systematic analysis is to indicate the effects of interventions performed by nurses by using the Health Belief Model (HBM) and Health Promotion Model (HPM) on the breast cancer early diagnosis behaviors and on the components of the Health Belief Model and Health Promotion Model. The reveiw was created in line with the Centre for Reviews and Dissemination guide dated 2009 (CRD) and developed by York University National Institute of Health Researches. Review was conducted by using PUBMED, OVID, EBSCO and COCHRANE databases. Six hundred seventy eight studies (PUBMED: 236, OVID: 162, EBSCO: 175, COCHRANE:105) were found in total at the end of the review. Abstracts and full texts of these six hundred seventy eight studies were evaluated in terms of inclusion and exclusion criteria and 9 studies were determined to meet the criteria. Samplings of the studies varied between ninety four and one thousand six hundred fifty five. It was detected in the studies that educations provided by taking the theories as basis became effective on the breast cancer early diagnosis behaviors. When the literature is examined, it is observed that the experimental researches which compare the concepts of Health Belief Model (HBM) and Health Promotion Model (HPM) preoperatively and postoperatively and show the effect of these concepts on education and are conducted by nurses are limited in number. Randomized controlled studies which compare HBM and HPM concepts preoperatively and postoperatively and show the efficiency of the interventions can be useful in evaluating the efficiency of the interventions.

  8. Effectiveness of an Articulated Knee Hyperextension Orthosis in Genu Recurvatum

    Directory of Open Access Journals (Sweden)

    Rahul ASRM

    2014-08-01

    Full Text Available Genu Recurvatum is a deformity of knee joint that tends to push it backwards by excessive extension in tibio-femoral joints. This poses a significant challenge because of technical difficulties and a high incidence of recurrence. This report describes a 63 years old male diagnosed as post-polio residual paralysis who showed excessive genu recurvatum of his left knee during long standing and walking. An Articulated Knee Hyperextension Orthosis (KAFO was tried to check its effectiveness in terms of gait and energy expenditure.

  9. [Prosthetic treatment of mandibular pseudarthrosis using an articulated prosthesis].

    Science.gov (United States)

    Sidibe, C A; Razouk, O; Dichamp, J; Bertrand, J C; Vaillant, J M

    1994-01-01

    Two cases with complete loss of the tooth-bearing portion of the mandible were repaired with a prosthesis. This type of defect can involve the loss of a large number of teeth and aggression to the remaining teeth must be limited as much as possible. A two-part "articulated" prosthesis with two rings appears to be the best adapted system. This method takes into account the requirements of for additional conventional prostheses and thus makes it possible to save the remaining teeth.

  10. The physics of articulated toys - a jumping and rotating kangaroo

    CERN Document Server

    Güémez, J

    2014-01-01

    We describe the physics of an articulated toy with an internal source of energy provided by a spiral spring. The toy is a funny low cost kangaroo which jumps and rotates. The study consists of a mechanical and a thermodynamical analysis which makes use of the Newton and center of mass equations, the rotational equations and the first law of thermodynamics. This amazing toy provides a nice demonstrative example how new physics insights can be brought about when links with thermodynamics are established in the study of mechanical systems.

  11. Gender Recognition from Unconstrained and Articulated Human Body

    Directory of Open Access Journals (Sweden)

    Qin Wu

    2014-01-01

    human body images acquired from an unconstrained environment in the real world. A systematic study of some critical issues in body-based gender recognition, such as which body parts are informative, how many body parts are needed to combine together, and what representations are good for articulated body-based gender recognition, is also presented. This paper also pursues data fusion schemes and efficient feature dimensionality reduction based on the partial least squares estimation. Extensive experiments are performed on two unconstrained databases which have not been explored before for gender recognition.

  12. A blind algorithm for recovering articulator positions from acoustics

    Energy Technology Data Exchange (ETDEWEB)

    Hogden, John E [Los Alamos National Laboratory

    2009-01-01

    MIMICRI is a signal-processing algorithm that has been shown to blindly infer and invert memoryless nonlinear functions of unobservable bandlimited signals, such as the mapping from the unobservable positions of the speech articulators to observable speech sounds. We review results of using MIMICRI on toy problems and on human speech data. We note that MIMICRI requires that the user specify two parameters: the dimensionality and pass-band of the unobservable signals. We show how to use cross-validation to help estimate the passband. An unexpected consequence of this work is that it helps separate signals with overlapping frequency bands.

  13. Agenda Setting for Health Promotion: Exploring an Adapted Model for the Social Media Era.

    Science.gov (United States)

    Albalawi, Yousef; Sixsmith, Jane

    2015-01-01

    The foundation of best practice in health promotion is a robust theoretical base that informs design, implementation, and evaluation of interventions that promote the public's health. This study provides a novel contribution to health promotion through the adaptation of the agenda-setting approach in response to the contribution of social media. This exploration and proposed adaptation is derived from a study that examined the effectiveness of Twitter in influencing agenda setting among users in relation to road traffic accidents in Saudi Arabia. The proposed adaptations to the agenda-setting model to be explored reflect two levels of engagement: agenda setting within the social media sphere and the position of social media within classic agenda setting. This exploratory research aims to assess the veracity of the proposed adaptations on the basis of the hypotheses developed to test these two levels of engagement. To validate the hypotheses, we collected and analyzed data from two primary sources: Twitter activities and Saudi national newspapers. Keyword mentions served as indicators of agenda promotion; for Twitter, interactions were used to measure the process of agenda setting within the platform. The Twitter final dataset comprised 59,046 tweets and 38,066 users who contributed by tweeting, replying, or retweeting. Variables were collected for each tweet and user. In addition, 518 keyword mentions were recorded from six popular Saudi national newspapers. The results showed significant ratification of the study hypotheses at both levels of engagement that framed the proposed adaptions. The results indicate that social media facilitates the contribution of individuals in influencing agendas (individual users accounted for 76.29%, 67.79%, and 96.16% of retweet impressions, total impressions, and amplification multipliers, respectively), a component missing from traditional constructions of agenda-setting models. The influence of organizations on agenda setting is

  14. Exploring Environmental Factors in Nursing Workplaces That Promote Psychological Resilience: Constructing a Unified Theoretical Model

    Science.gov (United States)

    Cusack, Lynette; Smith, Morgan; Hegney, Desley; Rees, Clare S.; Breen, Lauren J.; Witt, Regina R.; Rogers, Cath; Williams, Allison; Cross, Wendy; Cheung, Kin

    2016-01-01

    Building nurses' resilience to complex and stressful practice environments is necessary to keep skilled nurses in the workplace and ensuring safe patient care. A unified theoretical framework titled Health Services Workplace Environmental Resilience Model (HSWERM), is presented to explain the environmental factors in the workplace that promote nurses' resilience. The framework builds on a previously-published theoretical model of individual resilience, which identified the key constructs of psychological resilience as self-efficacy, coping and mindfulness, but did not examine environmental factors in the workplace that promote nurses' resilience. This unified theoretical framework was developed using a literary synthesis drawing on data from international studies and literature reviews on the nursing workforce in hospitals. The most frequent workplace environmental factors were identified, extracted and clustered in alignment with key constructs for psychological resilience. Six major organizational concepts emerged that related to a positive resilience-building workplace and formed the foundation of the theoretical model. Three concepts related to nursing staff support (professional, practice, personal) and three related to nursing staff development (professional, practice, personal) within the workplace environment. The unified theoretical model incorporates these concepts within the workplace context, linking to the nurse, and then impacting on personal resilience and workplace outcomes, and its use has the potential to increase staff retention and quality of patient care. PMID:27242567

  15. Mesenchymal stem cell therapy promotes the improvement and recovery of renal function in a preclinical model

    Directory of Open Access Journals (Sweden)

    Antônio Urt Filho

    2016-01-01

    Full Text Available Abstract Acute renal failure (ARF is an extremely important public health issue in need of novel therapies. The present study aimed to evaluate the capacity of mesenchymal stem cell (MSC therapy to promote the improvement and recovery of renal function in a preclinical model. Wistar rats were used as the experimental model, and our results show that cisplatin (5mg/kg can efficiently induce ARF, as measured by changes in biochemical (urea and creatinine and histological parameters. MSC therapy performed 24h after the administration of chemotherapy resulted in normalized plasma urea and creatinine levels 30 and 45d after the onset of kidney disease. Furthermore, MSC therapy significantly reduced histological changes (intratubular cast formation in protein overload nephropathy and tubular hydropic degeneration in this ARF model. Thus, considering that current therapies for ARF are merely palliative and that MSC therapy can promote the improvement and recovery of renal function in this model system, we suggest that innovative/alternative therapies involving MSCs should be considered for clinical studies in humans to treat ARF.

  16. Exploring Environmental Factors in Nursing Workplaces That Promote Psychological Resilience: Constructing a Unified Theoretical Model.

    Science.gov (United States)

    Cusack, Lynette; Smith, Morgan; Hegney, Desley; Rees, Clare S; Breen, Lauren J; Witt, Regina R; Rogers, Cath; Williams, Allison; Cross, Wendy; Cheung, Kin

    2016-01-01

    Building nurses' resilience to complex and stressful practice environments is necessary to keep skilled nurses in the workplace and ensuring safe patient care. A unified theoretical framework titled Health Services Workplace Environmental Resilience Model (HSWERM), is presented to explain the environmental factors in the workplace that promote nurses' resilience. The framework builds on a previously-published theoretical model of individual resilience, which identified the key constructs of psychological resilience as self-efficacy, coping and mindfulness, but did not examine environmental factors in the workplace that promote nurses' resilience. This unified theoretical framework was developed using a literary synthesis drawing on data from international studies and literature reviews on the nursing workforce in hospitals. The most frequent workplace environmental factors were identified, extracted and clustered in alignment with key constructs for psychological resilience. Six major organizational concepts emerged that related to a positive resilience-building workplace and formed the foundation of the theoretical model. Three concepts related to nursing staff support (professional, practice, personal) and three related to nursing staff development (professional, practice, personal) within the workplace environment. The unified theoretical model incorporates these concepts within the workplace context, linking to the nurse, and then impacting on personal resilience and workplace outcomes, and its use has the potential to increase staff retention and quality of patient care.

  17. Children affected by HIV/AIDS: SAFE, a model for promoting their security, health, and development.

    Science.gov (United States)

    Betancourt, Theresa S; Fawzi, Mary K S; Bruderlein, Claude; Desmond, Chris; Kim, Jim Y

    2010-05-01

    A human security framework posits that individuals are the focus of strategies that protect the safety and integrity of people by proactively promoting children's well being, placing particular emphasis on prevention efforts and health promotion. This article applies this framework to a rights-based approach in order to examine the health and human rights of children affected by HIV/AIDS. The SAFE model describes sources of insecurity faced by children across four fundamental dimensions of child well-being and the survival strategies that children and families may employ in response. The SAFE model includes: Safety/protection; Access to health care and basic physiological needs; Family/connection to others; and Education/livelihoods. We argue that it is critical to examine the situation of children through an integrated lens that effectively looks at human security and children's rights through a holistic approach to treatment and care rather than artificially limiting our scope of work to survival-oriented interventions for children affected by HIV/AIDS. Interventions targeted narrowly at children, in isolation of their social and communal environment as outlined in the SAFE model, may in fact undermine protective resources in operation in families and communities and present additional threats to children's basic security. An integrated approach to the basic security and care of children has implications for the prospects of millions of children directly infected or indirectly affected by HIV/AIDS around the world. The survival strategies that young people and their families engage in must be recognized as a roadmap for improving their protection and promoting healthy development. Although applied to children affected by HIV/AIDS in the present analysis, the SAFE model has implications for guiding the care and protection of children and families facing adversity due to an array of circumstances from armed conflict and displacement to situations of extreme poverty.

  18. Construction of predictive promoter models on the example of antibacterial response of human epithelial cells

    Directory of Open Access Journals (Sweden)

    Wingender Edgar

    2005-01-01

    Full Text Available Abstract Background Binding of a bacteria to a eukaryotic cell triggers a complex network of interactions in and between both cells. P. aeruginosa is a pathogen that causes acute and chronic lung infections by interacting with the pulmonary epithelial cells. We use this example for examining the ways of triggering the response of the eukaryotic cell(s, leading us to a better understanding of the details of the inflammatory process in general. Results Considering a set of genes co-expressed during the antibacterial response of human lung epithelial cells, we constructed a promoter model for the search of additional target genes potentially involved in the same cell response. The model construction is based on the consideration of pair-wise combinations of transcription factor binding sites (TFBS. It has been shown that the antibacterial response of human epithelial cells is triggered by at least two distinct pathways. We therefore supposed that there are two subsets of promoters activated by each of them. Optimally, they should be "complementary" in the sense of appearing in complementary subsets of the (+-training set. We developed the concept of complementary pairs, i.e., two mutually exclusive pairs of TFBS, each of which should be found in one of the two complementary subsets. Conclusions We suggest a simple, but exhaustive method for searching for TFBS pairs which characterize the whole (+-training set, as well as for complementary pairs. Applying this method, we came up with a promoter model of antibacterial response genes that consists of one TFBS pair which should be found in the whole training set and four complementary pairs. We applied this model to screening of 13,000 upstream regions of human genes and identified 430 new target genes which are potentially involved in antibacterial defense mechanisms.

  19. Modeling keratinocyte wound healing dynamics: Cell-cell adhesion promotes sustained collective migration.

    Science.gov (United States)

    Nardini, John T; Chapnick, Douglas A; Liu, Xuedong; Bortz, David M

    2016-07-07

    The in vitro migration of keratinocyte cell sheets displays behavioral and biochemical similarities to the in vivo wound healing response of keratinocytes in animal model systems. In both cases, ligand-dependent Epidermal Growth Factor Receptor (EGFR) activation is sufficient to elicit collective cell migration into the wound. Previous mathematical modeling studies of in vitro wound healing assays assume that physical connections between cells have a hindering effect on cell migration, but biological literature suggests a more complicated story. By combining mathematical modeling and experimental observations of collectively migrating sheets of keratinocytes, we investigate the role of cell-cell adhesion during in vitro keratinocyte wound healing assays. We develop and compare two nonlinear diffusion models of the wound healing process in which cell-cell adhesion either hinders or promotes migration. Both models can accurately fit the leading edge propagation of cell sheets during wound healing when using a time-dependent rate of cell-cell adhesion strength. The model that assumes a positive role of cell-cell adhesion on migration, however, is robust to changes in the leading edge definition and yields a qualitatively accurate density profile. Using RNAi for the critical adherens junction protein, α-catenin, we demonstrate that cell sheets with wild type cell-cell adhesion expression maintain migration into the wound longer than cell sheets with decreased cell-cell adhesion expression, which fails to exhibit collective migration. Our modeling and experimental data thus suggest that cell-cell adhesion promotes sustained migration as cells pull neighboring cells into the wound during wound healing.

  20. Audiovisual materials are effective for enhancing the correction of articulation disorders in children with cleft palate.

    Science.gov (United States)

    Pamplona, María Del Carmen; Ysunza, Pablo Antonio; Morales, Santiago

    2017-02-01

    Children with cleft palate frequently show speech disorders known as compensatory articulation. Compensatory articulation requires a prolonged period of speech intervention that should include reinforcement at home. However, frequently relatives do not know how to work with their children at home. To study whether the use of audiovisual materials especially designed for complementing speech pathology treatment in children with compensatory articulation can be effective for stimulating articulation practice at home and consequently enhancing speech normalization in children with cleft palate. Eighty-two patients with compensatory articulation were studied. Patients were randomly divided into two groups. Both groups received speech pathology treatment aimed to correct articulation placement. In addition, patients from the active group received a set of audiovisual materials to be used at home. Parents were instructed about strategies and ideas about how to use the materials with their children. Severity of compensatory articulation was compared at the onset and at the end of the speech intervention. After the speech therapy period, the group of patients using audiovisual materials at home demonstrated significantly greater improvement in articulation, as compared with the patients receiving speech pathology treatment on - site without audiovisual supporting materials. The results of this study suggest that audiovisual materials especially designed for practicing adequate articulation placement at home can be effective for reinforcing and enhancing speech pathology treatment of patients with cleft palate and compensatory articulation. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  1. A kinematic study of critical and non-critical articulators in emotional speech production.

    Science.gov (United States)

    Kim, Jangwon; Toutios, Asterios; Lee, Sungbok; Narayanan, Shrikanth S

    2015-03-01

    This study explores one aspect of the articulatory mechanism that underlies emotional speech production, namely, the behavior of linguistically critical and non-critical articulators in the encoding of emotional information. The hypothesis is that the possible larger kinematic variability in the behavior of non-critical articulators enables revealing underlying emotional expression goal more explicitly than that of the critical articulators; the critical articulators are strictly controlled in service of achieving linguistic goals and exhibit smaller kinematic variability. This hypothesis is examined by kinematic analysis of the movements of critical and non-critical speech articulators gathered using eletromagnetic articulography during spoken expressions of five categorical emotions. Analysis results at the level of consonant-vowel-consonant segments reveal that critical articulators for the consonants show more (less) peripheral articulations during production of the consonant-vowel-consonant syllables for high (low) arousal emotions, while non-critical articulators show less sensitive emotional variation of articulatory position to the linguistic gestures. Analysis results at the individual phonetic targets show that overall, between- and within-emotion variability in articulatory positions is larger for non-critical cases than for critical cases. Finally, the results of simulation experiments suggest that the postural variation of non-critical articulators depending on emotion is significantly associated with the controls of critical articulators.

  2. The oldest articulated chondrichthyan from the Early Devonian period.

    Science.gov (United States)

    Miller, Randall F; Cloutier, Richard; Turner, Susan

    2003-10-01

    Chondrichthyans (including living sharks, skates, rays and chimaeras) have a fossil record of scales and dermal denticles perhaps dating back to the Late Ordovician period, about 455 million years ago. Their fossil tooth record extends to the earliest Devonian period, almost 418 million years ago, whereas the oldest known articulated shark remains date from the Early Devonian period, about 394 million years ago. Here we report the discovery of an articulated shark that is almost 409 million years old from the Early Devonian (early Emsian) period of New Brunswick, Canada. The specimen, identified as Doliodus problematicus (Woodward), sheds light on the earliest chondrichthyans and their interrelationships with basal jawed vertebrates. This species has been truly problematic. Previously known only from isolated teeth, it has been identified as an acanthodian and a chondrichthyan. This specimen is the oldest shark showing the tooth families in situ, and preserves one of the oldest chondrichthyan braincases. More notably, it shows the presence of paired pectoral fin-spines, previously unknown in cartilaginous fishes.

  3. Vowel formant dispersion as a measure of articulation proficiency.

    Science.gov (United States)

    Karlsson, Fredrik; van Doorn, Jan

    2012-10-01

    The articulatory range of a speaker has previously been estimated by the shape formed by first and second formant measurements of produced vowels. In a majority of the currently available metrics, formant frequency measurements are reduced to a single estimate for a condition, which has adverse consequences for subsequent statistical testing. Other metrics provide estimates of size of vowel articulation changes only, and do not provide a method for studying the direction of the change. This paper proposes an alternative approach. Vowel formant frequencies are redefined as vectors originating from a defined center point of the vowel space fixed to a basic three-vowel frame. The Euclidean length of the vectors, the vowel formant dispersion (VFD), can be compared across conditions for evidence of articulatory expansions or reductions across conditions or speaker groups. Further, the angle component of the vowel vectors allows for analyses of direction of the reduction or expansion. Based on the range of investigations afforded by the VFD metric, and simulation experiments that compare its statistical properties with those of other proposed metrics, it is argued that the VFD procedure offers an enhanced view of vowel articulation change over rival metrics.

  4. Interacting effects of syllable and phrase position on consonant articulation

    Science.gov (United States)

    Byrd, Dani; Lee, Sungbok; Riggs, Daylen; Adams, Jason

    2005-12-01

    The complexities of how prosodic structure, both at the phrasal and syllable levels, shapes speech production have begun to be illuminated through studies of articulatory behavior. The present study contributes to an understanding of prosodic signatures on articulation by examining the joint effects of phrasal and syllable position on the production of consonants. Articulatory kinematic data were collected for five subjects using electromagnetic articulography (EMA) to record target consonants (labial, labiodental, and tongue tip), located in (1) either syllable final or initial position and (2) either at a phrase edge or phrase medially. Spatial and temporal characteristics of the consonantal constriction formation and release were determined based on kinematic landmarks in the articulator velocity profiles. The results indicate that syllable and phrasal position consistently affect the movement duration; however, effects on displacement were more variable. For most subjects, the boundary-adjacent portions of the movement (constriction release for a preboundary coda and constriction formation for a postboundary onset) are not differentially affected in terms of phrasal lengthening-both lengthen comparably.

  5. Articulated navigation testbed (ANT): an example of adaptable intrinsic mobility

    Science.gov (United States)

    Brosinsky, Chris A.; Hanna, Doug M.; Penzes, Steven G.

    2000-07-01

    An important but oft overlooked aspect of any robotic system is the synergistic benefit of designing the chassis to have high intrinsic mobility which complements rather than limits, its system capabilities. This novel concept continues to be investigated by the Defence Research Establishment Suffield (DRES) with the Articulated Navigation Testbed (ANT) Unmanned Ground Vehicle (UGV). The ANT demonstrates high mobility through the combination of articulated steering and a hybrid locomotion scheme which utilizes individually powered wheels on the edge of rigid legs; legs which are capable of approximately 450 degrees of rotation. The configuration can be minimally configured as a 4x4 and modularly expanded to 6x6, 8x8, and so on. This enhanced mobility configuration permits pose control and novel maneuvers such as stepping, bridging, crawling, etc. Resultant mobility improvements, particularly in unstructured and off-road environments, will reduce the resolution with which the UGV sensor systems must perceive its surroundings and decreases the computational requirements of the UGV's perception systems1 for successful semi-autonomous or autonomous terrain negotiation. This paper reviews critical vehicle developments leading up to the ANT concept, describes the basis for its configuration and speculates on the impact of the intrinsic mobility concept for UGV effectiveness.

  6. Promoting health behavior change using appreciative inquiry: moving from deficit models to affirmation models of care.

    Science.gov (United States)

    Moore, Shirley M; Charvat, Jacqueline

    2007-01-01

    This article describes a new theoretical approach to health promotion and behavior change that may be especially suited to underserved women. Appreciative inquiry (AI), an organizational development process that focuses on the positive and creative as a force for an improved future, is described and adapted for use as an intervention to achieve health behavior change at the individual level. Guiding principles for its use with clients are provided, and an example of its application is illustrated in a hypothetical case study of an African American woman of low-socioeconomic resources who is attempting to increase lifestyle exercise following a cardiac event. AI is contrasted with the more traditional problem-solving approaches to the provision of care. The advantages, challenges, and issues associated with the use of AI as a health behavior change strategy are discussed.

  7. An iterative strategy combining biophysical criteria and duration hidden Markov models for structural predictions of Chlamydia trachomatis σ66 promoters

    Directory of Open Access Journals (Sweden)

    Ojcius David M

    2009-08-01

    Full Text Available Abstract Background Promoter identification is a first step in the quest to explain gene regulation in bacteria. It has been demonstrated that the initiation of bacterial transcription depends upon the stability and topology of DNA in the promoter region as well as the binding affinity between the RNA polymerase σ-factor and promoter. However, promoter prediction algorithms to date have not explicitly used an ensemble of these factors as predictors. In addition, most promoter models have been trained on data from Escherichia coli. Although it has been shown that transcriptional mechanisms are similar among various bacteria, it is quite possible that the differences between Escherichia coli and Chlamydia trachomatis are large enough to recommend an organism-specific modeling effort. Results Here we present an iterative stochastic model building procedure that combines such biophysical metrics as DNA stability, curvature, twist and stress-induced DNA duplex destabilization along with duration hidden Markov model parameters to model Chlamydia trachomatis σ66 promoters from 29 experimentally verified sequences. Initially, iterative duration hidden Markov modeling of the training set sequences provides a scoring algorithm for Chlamydia trachomatis RNA polymerase σ66/DNA binding. Subsequently, an iterative application of Stepwise Binary Logistic Regression selects multiple promoter predictors and deletes/replaces training set sequences to determine an optimal training set. The resulting model predicts the final training set with a high degree of accuracy and provides insights into the structure of the promoter region. Model based genome-wide predictions are provided so that optimal promoter candidates can be experimentally evaluated, and refined models developed. Co-predictions with three other algorithms are also supplied to enhance reliability. Conclusion This strategy and resulting model support the conjecture that DNA biophysical properties

  8. Upending the social ecological model to guide health promotion efforts toward policy and environmental change.

    Science.gov (United States)

    Golden, Shelley D; McLeroy, Kenneth R; Green, Lawrence W; Earp, Jo Anne L; Lieberman, Lisa D

    2015-04-01

    Efforts to change policies and the environments in which people live, work, and play have gained increasing attention over the past several decades. Yet health promotion frameworks that illustrate the complex processes that produce health-enhancing structural changes are limited. Building on the experiences of health educators, community activists, and community-based researchers described in this supplement and elsewhere, as well as several political, social, and behavioral science theories, we propose a new framework to organize our thinking about producing policy, environmental, and other structural changes. We build on the social ecological model, a framework widely employed in public health research and practice, by turning it inside out, placing health-related and other social policies and environments at the center, and conceptualizing the ways in which individuals, their social networks, and organized groups produce a community context that fosters healthy policy and environmental development. We conclude by describing how health promotion practitioners and researchers can foster structural change by (1) conveying the health and social relevance of policy and environmental change initiatives, (2) building partnerships to support them, and (3) promoting more equitable distributions of the resources necessary for people to meet their daily needs, control their lives, and freely participate in the public sphere.

  9. Promotion effect of sulfite on deoxyosones and 4-methylimidazole in caramel model system.

    Science.gov (United States)

    Xu, Xian-Bing; Yu, Pei; Yu, Shu-Juan

    2017-05-15

    In this study, hydrogen-deuterium (H/D) exchange experiment was carried out to reveal the promotion effect of sulfite on the formation of deoxyosones and 4-methylimidazole (4-MeI) in the Maillard reaction. Glucose-ammonium (40mmol/L, pH 7.4 in PBS) model systems with different levels of sulfite were incubated at 110°C for 2h. Alpha-dicarbonyls were detected after derivatization by a high-performance liquid chromatography with a diode array detector (HPLC-DAD). 4-MeI in the Maillard reaction was tested using a high-performance anion exchange chromatography with an electrochemical detector (HPAEC-ED). The H/D exchange ratios of hexose (fructose, glucose and mannose) were tested by HPAEC-MS. Results showed that the aldo-enol transition of enediol was promoted by sulfite, which promoted the formation of deoxyosones and 4-MeI. In addition, the oxidation reaction of enediols was inhibited by the antioxidant sulfite, which caused the inhibition of osones formation in the Maillard reaction. Copyright © 2016 Elsevier Ltd. All rights reserved.

  10. Speech Articulator and User Gesture Measurements Using Micropower, Interferometric EM-Sensors

    Energy Technology Data Exchange (ETDEWEB)

    Holzrichter, J F; Ng, L C

    2001-02-06

    Very low power, GHz frequency, ''radar-like'' sensors can measure a variety of motions produced by a human user of machine interface devices. These data can be obtained ''at a distance'' and can measure ''hidden'' structures. Measurements range from acoustic induced, 10-micron amplitude vibrations of vocal tract tissues, to few centimeter human speech articulator motions, to meter-class motions of the head, hands, or entire body. These EM sensors measure ''fringe motions'' as reflected EM waves are mixed with a local (homodyne) reference wave. These data, when processed using models of the system being measured, provide real time states of interface positions or other targets vs. time. An example is speech articulator positions vs. time in the user's body. This information appears to be useful for a surprisingly wide range of applications ranging from speech coding synthesis and recognition, speaker or object identification, noise cancellation, hand or head motions for cursor direction, and other applications.

  11. Speech Articulator and User Gesture Measurements Using Micropower, Interferometric EM-Sensore

    Energy Technology Data Exchange (ETDEWEB)

    Holzrichter, J.F.

    2000-09-15

    Very low power, GHz frequency, ''radar-like'' sensors can measure a variety of motions produced by a human user of machine interface devices. These data can be obtained ''at a distance'' and can measure ''hidden'' structures. Measurements range from acoustic induced 10-micron amplitude vibrations of vocal tract tissues, to few centimeter human speech articulator motions, to meter-class motions of the head, hands, or entire body. These EM sensors measure ''fringe motions' as reflected EM waves are mixed with a local (homodyne) reference wave. These data, when processed using models of the system being measured, provide real time states of interface positions vs. time. An example is speech articulator positions vs. time in the user's body. This information appears to be useful for a surprisingly wide range of applications ranging from speech coding and recognition, speaker or object identification, noise cancellation, hand or head motions for cursor direction, and other applications.

  12. Beam rider for an Articulated Robot Manipulator (ARM) accurate positioning of long flexible manipulators

    Science.gov (United States)

    Malachowski, M. J.

    1990-01-01

    Laser beam positioning and beam rider modules were incorporated into the long hollow flexible segment of an articulated robot manipulator (ARM). Using a single laser beam, the system determined the position of the distal ARM endtip, with millimetric precision, in six degrees of freedom, at distances of up to 10 meters. Preliminary designs, using space rated technology for the critical systems, of a two segmented physical ARM, with a single and a dual degree of freedom articulation, were developed, prototyped, and tested. To control the positioning of the physical ARM, an indirect adaptive controller, which used the mismatch between the position of the laser beam under static and dynamic conditions, was devised. To predict the behavior of the system and test the concept, a computer simulation model was constructed. A hierarchical artificially intelligent real time ADA operating system program structure was created. The software was designed for implementation on a dedicated VME bus based Intel 80386 administered parallel processing multi-tasking computer system.

  13. Can health promotion model constructs predict nutritional behavior among diabetic patients?

    Directory of Open Access Journals (Sweden)

    Siamak Mohebi

    2013-01-01

    Full Text Available Since, the nutritional behavior is a complicated process in which various factors play the role, this study aimed at specifying the effective factors in nutritional behavior of diabetic patients based on Health Promotion Model. This paper reviews the published articles from 2000 to the beginning of 2012, using the various data banks and search engines such as PubMed, ProQuest, Scopus, Elsevier, and the key words" perceived benefits and barriers, perceived self-efficacy, social support, activity related affect, situational influences, commitment to plan of action, immediate competing demands and diabetes, self-caring and diabetes. Unfavorable self-care situation especially, inappropriate nutritional behavior is related to some effective modifiable factors. Perceived benefits and self-efficacy regarding behaviors play a major role in the nutritional behaviors. Social support especially, spouses′ support has a significant role in this regard. Moreover, there is a reverse relationship between perceived barriers and nutritional self-care. In addition, behavioral feelings, situational influences, commitment to plan of action and immediate competing demands and preferences can also impact and overshadow the nutritional self-care. Following the relationship between constructs of Health Promotion Model and nutritional behavior the constructs of this model can be utilized as the basis for educational intervention among diabetes.

  14. Can health promotion model constructs predict nutritional behavior among diabetic patients?

    Science.gov (United States)

    Mohebi, Siamak; Sharifirad, Ghlamreza; Feizi, Avat; Botlani, Saeedeh; Hozori, Mohammad; Azadbakht, Leila

    2013-04-01

    Since, the nutritional behavior is a complicated process in which various factors play the role, this study aimed at specifying the effective factors in nutritional behavior of diabetic patients based on Health Promotion Model. This paper reviews the published articles from 2000 to the beginning of 2012, using the various data banks and search engines such as PubMed, ProQuest, Scopus, Elsevier, and the key words" perceived benefits and barriers, perceived self-efficacy, social support, activity related affect, situational influences, commitment to plan of action, immediate competing demands and diabetes, self-caring and diabetes. Unfavorable self-care situation especially, inappropriate nutritional behavior is related to some effective modifiable factors. Perceived benefits and self-efficacy regarding behaviors play a major role in the nutritional behaviors. Social support especially, spouses' support has a significant role in this regard. Moreover, there is a reverse relationship between perceived barriers and nutritional self-care. In addition, behavioral feelings, situational influences, commitment to plan of action and immediate competing demands and preferences can also impact and overshadow the nutritional self-care. Following the relationship between constructs of Health Promotion Model and nutritional behavior the constructs of this model can be utilized as the basis for educational intervention among diabetes.

  15. Utilising the Hand Model to promote a culturally safe environment for international nursing students.

    Science.gov (United States)

    Mackay, Bev; Harding, Thomas; Jurlina, Lou; Scobie, Norma; Khan, Ruelle

    2011-04-01

    The rising number of international students studying outside their own country poses challenges for nursing education. Numbers are predicted to grow and economic factors are placing increasing pressure on tertiary institutions to accept these students. In adapting to a foreign learning environment international students must not only adapt to the academic culture but also to the socio-cultural context. The most significant acculturation issues for students are English as a second language, differences in education pedagogy and social integration and connectedness. Students studying in New Zealand need to work with Maori, the indigenous people, and assimilate and practice the unique aspects of cultural safety, which has evolved in nursing as part of the response to the principles underpinning the Treaty of Waitangi. The Hand Model offers the potential to support international students in a culturally safe manner across all aspects of acculturation including those aspects of cultural safety unique to New Zealand. The model was originally developed by Lou Jurlina, a nursing teacher, to assist her to teach cultural safety and support her students in practising cultural safety in nursing. The thumb, represents 'awareness', with the other four digits signifying 'connection" 'communication', 'negotiation' and 'advocacy' respectively. Each digit is connected to the palm where the ultimate evaluation of the Hand Model in promoting cultural safety culminates in the clasping and shaking of hands: the moment of shared meaning. It promotes a sense of self worth and identity in students and a safe environment in which they can learn.

  16. Utilising the Hand Model to promote a culturally safe environment for international nursing students.

    Science.gov (United States)

    Mackay, Bev; Harding, Thomas; Jurlina, Lou; Scobie, Norma; Khan, Ruelle

    2012-03-01

    The rising number of international students studying outside their own country poses challenges for nursing education. Numbers are predicted to grow and economic factors are placing increasing pressure on tertiary institutions to accept these students. In adapting to a foreign learning environment international students must not only adapt to the academic culture but also to the social cultural context. The most significant acculturation issues for students are English as a second language, differences in education pedagogy and social integration and connectedness. Students studying in New Zealand need to work with Māori, the indigenous people, and assimilate and practice the unique aspects of cultural safety, which has evolved in nursing as part of the response to the principles underpinning the Treaty of Waitangi. The Hand Model offers the potential to support international nursing students in a culturally safe manner across all aspects of acculturation including those aspects of cultural safety unique to New Zealand. The model was originally developed by Lou Jurlina, a nursing teacher, to assist her to teach cultural safety and support her students in practising cultural safety in nursing. The thumb, represents 'awareness', with the other four digits signifying 'connection', 'communication', 'negotiation' and 'advocacy' respectively. Each digit is connected to the palm where the ultimate evaluation of The Hand Model in promoting cultural safety culminates in the clasping and shaking of hands: the moment of shared meaning. It promotes a sense of self worth and identity in students and a safe environment in which they can learn.

  17. A Proposed Model for Infant and Child Oral Health Promotion in India

    Science.gov (United States)

    Jawdekar, Ashwin Muralidhar

    2013-01-01

    Dental caries is an increasing burden in the developing countries. A proper budgetary allocation for treating dental diseases in an enormous population such as India is impractical, where resources are inadequate for major health challenges such as malnutrition and gastrointestinal and respiratory infections in children. An integrated, directed population approach targeting children is much needed. The existing machinery of successful public health campaigns such as the “Pulse Polio” and the “Mid-Day-Meals Scheme” of the Government of India can be used for oral health promotion for children. India has about 300 dental colleges and countrywide branches of the Indian Dental Association that can provide manpower for the program. An innovative, large-scale “Fit for School” program in Philippines is a model for an integrated approach for children's health and has proved to be cost-effective and viable. A model for oral health promotion in infants and children of India, combining age-specific initiatives for health education, nutrition, hygiene, and fluoride use, is proposed. The model could be implemented to evaluate the oral health status of children, knowledge and knowledge gain of the community health workers, and acceptability and sustainability of the preventive programs (fluoride varnish and preschool and school tooth brushing) pragmatically. PMID:24288533

  18. Testing the health promotion model for adherence and quality of life in individuals with multiple sclerosis.

    Science.gov (United States)

    Penwell-Waines, Lauren; Lewis, Kimberly; Valvano, Abbey; Smith, Suzanne; Rahn, Rebecca; Stepleman, Lara

    2017-02-01

    The nature of multiple sclerosis (MS) presents challenges to health-promoting behaviors (e.g. adherence) and quality of life. The Health Promotion Model (HPM) proposes that these outcomes are explained by individual characteristics (i.e. biological, social, psychological) and behavior-specific cognitions (e.g. self-efficacy). The current study sought to test the HPM in explaining self-reported adherence and MS quality of life among 121 MS patients receiving care in an MS clinic in the southeastern United States. Hierarchical regression models partially supported the HPM for adherence (R(2) = .27) and more fully for quality of life (QoL) (R(2) = .64). Depression and stigma were among the variables most strongly related to both adherence and QoL; contrary to HPM theory, self-efficacy was not significantly related to adherence but was to QoL. Thus, the HPM may help to guide strategies used to improve QoL among individuals living with MS; however, the model may need further refinement to be used with adherence.

  19. A Proposed Model for Infant and Child Oral Health Promotion in India

    Directory of Open Access Journals (Sweden)

    Ashwin Muralidhar Jawdekar

    2013-01-01

    Full Text Available Dental caries is an increasing burden in the developing countries. A proper budgetary allocation for treating dental diseases in an enormous population such as India is impractical, where resources are inadequate for major health challenges such as malnutrition and gastrointestinal and respiratory infections in children. An integrated, directed population approach targeting children is much needed. The existing machinery of successful public health campaigns such as the “Pulse Polio” and the “Mid-Day-Meals Scheme” of the Government of India can be used for oral health promotion for children. India has about 300 dental colleges and countrywide branches of the Indian Dental Association that can provide manpower for the program. An innovative, large-scale “Fit for School” program in Philippines is a model for an integrated approach for children’s health and has proved to be cost-effective and viable. A model for oral health promotion in infants and children of India, combining age-specific initiatives for health education, nutrition, hygiene, and fluoride use, is proposed. The model could be implemented to evaluate the oral health status of children, knowledge and knowledge gain of the community health workers, and acceptability and sustainability of the preventive programs (fluoride varnish and preschool and school tooth brushing pragmatically.

  20. Approach Choice and Innovative Model Design of Grass-root Agricultural Technology Promotion under the View of New Countryside

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    This paper introduces the approach types of agricultural technology promotion we can choose in the process of new countryside construction, and there are mainly 6 types, namely government-domination-oriented approach, market-development-oriented approach, university (scientific research institution)-education-oriented approach, farmers’ participation-oriented approach, direct-training-oriented approach and individual-service-oriented approach, including 20 models. The problems existing in the grass-root agricultural technology promotion in the process of new village construction are analyzed as follows: the awareness of innovation is not strong; scientific research, education, and promotion are disjointed; the construction of specific work system lags behind; the structure of promotion team is irrational, and the quality of promotion personnel is yet to be promoted; the cultural quality of farmers is low, and the cooperative organizations are not sound; the working conditions are poor, and the basic security is inadequate; the investment channel is simple and the supply amount is badly short; the methods of agricultural technology promotion do not adapt to the requirements of new situation. According to the characteristics and internal requirements of grass-root agricultural technology promotion, we creatively design an overall working model, and put forward new measures from objective of grass-root agricultural technology promotion, service object, service content, organization work and scope, method, role of agricultural technology personnel and so on.

  1. Structure and algorithm of hybrid control in cerebella model articulation controller for electric loading system%新型小脑模型关联控制器复合控制在电动加载系统中的结构及算法

    Institute of Scientific and Technical Information of China (English)

    杨波,; 王哲

    2011-01-01

    在电动加载系统中,多余力矩强扰动和其他非线性因素直接影响力矩跟踪精度,传统的控制方法很难得到满意的控制效果.本文分析了电动加载系统中多余力矩产生机理,提出了一种新型小脑模型关联控制器(CMAC)复合控制策略,并对其结构及算法进行了研究.在控制结构上以系统的指令输入和实际输出作为CMAC的激励信号,采用误差作为训练信号,并根据激励信号的特点,提出了非均匀量化的思想.不同于常规CMAC的误差平均分配,新型CMAC根据高斯权重系数来分配误差.动态仿真结果表明,该方法有效抑制了加载系统的多余力矩及摩擦等非线性因素干扰,提高了电动加载系统的控制精度,增强了系统的稳定性.%The disturbance of surplus torque and the nonlinearity deteriorate the precision of torque tracking in the electric loading system. This undesired effect can not be removed satisfactorily by the conventional control. To deal with this problem, after analyzing the effect of surplus torque on the electric loading system, we propose a hybrid control based on the novel cerebella model articulation controller(CMAC) and investigate its structure and algorithm. This control adopts the desired output and the actual output of the electric loading system as the incentive signals of CMAC, and treats the error between the desired output and the actual output as the training signal for the CMAC structure. A non-uniform quantization scheme is then proposed according to the characteristics of the incentive signals. In the conventional CMAC, errors are equally distributed into memory cells; while the novel CMAC allocates errors according to the Gaussian weighting coefficients. Simulation results show that the proposed hybrid controller effectively suppresses the disturbance of surplus torque and the nonlinearity such as friction, improves the control precision of the electric loading system and enhances the

  2. FXN Promoter Silencing in the Humanized Mouse Model of Friedreich Ataxia.

    Directory of Open Access Journals (Sweden)

    Yogesh K Chutake

    Full Text Available Friedreich ataxia is caused by an expanded GAA triplet-repeat sequence in intron 1 of the FXN gene that results in epigenetic silencing of the FXN promoter. This silencing mechanism is seen in patient-derived lymphoblastoid cells but it remains unknown if it is a widespread phenomenon affecting multiple cell types and tissues.The humanized mouse model of Friedreich ataxia (YG8sR, which carries a single transgenic insert of the human FXN gene with an expanded GAA triplet-repeat in intron 1, is deficient for FXN transcript when compared to an isogenic transgenic mouse lacking the expanded repeat (Y47R. We found that in YG8sR the deficiency of FXN transcript extended both upstream and downstream of the expanded GAA triplet-repeat, suggestive of deficient transcriptional initiation. This pattern of deficiency was seen in all tissues tested, irrespective of whether they are known to be affected or spared in disease pathogenesis, in both neuronal and non-neuronal tissues, and in cultured primary fibroblasts. FXN promoter function was directly measured via metabolic labeling of newly synthesized transcripts in fibroblasts, which revealed that the YG8sR mouse was significantly deficient in transcriptional initiation compared to the Y47R mouse.Deficient transcriptional initiation accounts for FXN transcriptional deficiency in the humanized mouse model of Friedreich ataxia, similar to patient-derived cells, and the mechanism underlying promoter silencing in Friedreich ataxia is widespread across multiple cell types and tissues.

  3. Evaluation of accuracy of transfer of the maxillary occlusal cant of two articulators using two facebow/semi-adjustable articulator systems: An in vivo study

    Directory of Open Access Journals (Sweden)

    Sanath Shetty

    2016-01-01

    Full Text Available Aim: The aim of this study was to compare the accuracy of the angle made by Frankfort horizontal plane-occlusal plane on maxillary casts, mounted using the respective facebows on Artex Amann Girrbach and Hanau Wide-vue semi-adjustable articulators with cephalometrically derived Frankfort horizontal plane-occlusal plane angle as a control. Subjects and Methods: Maxillary casts of 30 subjects were mounted on Hanau Wide-vue and Artex Amann Girrbach semi-adjustable articulators following facebow transfer using respective facebows. The Frankfort horizontal plane-occlusal plane angles of these casts were measured using Wixey's digital angle gauge. They were also subjected to a lateral cephalogram, and the occlusal cant was measured using RadiAnt DICOM software. Statistical Analysis: Using Pearson correlation, the accuracy of the angle made by upper member of the articulator and occlusal plane of mounted maxillary casts in each of the articulator was compared to the Frankfort horizontal plane-occlusal plane angle in lateral cephalogram. Results: A mean difference of 1.9° was found between Hanau Wide-vue articulator and lateral cephalogram and a mean difference of 3.6° was found between Artex Amann Girrbach articulator and lateral cephalogram. Statistically, Pearson correlation value (r obtained between Hanau Wide-vue and lateral cephalogram was 0.46 and between Artex Amann Girrbach and lateral cephalogram was 0.25. Conclusion: From the statistical value (r derived, it can be inferred that the Frankfort horizontal plane-occlusal plane angle of the casts articulated on Hanau Wide-vue articulator was more accurate in comparison to that on Artex Amann Girrbach articulator.

  4. Informal work and formal plans: articulating the active role of patients in cancer trajectories

    DEFF Research Database (Denmark)

    Dalsted, Rikke Juul; Hølge-Hazelton, Bibi; Brostrøm Kousgaard, Marius

    2012-01-01

    . The patients’ requests were not sufficiently supported in the professional organisation of work or formal planning. Patients’ insertion and use of information in their trajectories challenged professional views and working processes. And the design of the formal pathway models limits the patients´ active......Introduction: Formal pathway models outline that patients should receive information in order to experience a coherent journey but do not describe an active role for patients or their relatives. The aim of this is paper is to articulate and discuss the active role of patients during their cancer...... and care. They initiated processes in the trajectories, and acquired information, which they used to form their trajectories. Patients presented problems to the healthcare professionals in order to get proper help when needed. Discussion: Work done by patients was invisible and not perceived as work...

  5. Material opportunities for children’s participation, articulation and re-experiencing

    DEFF Research Database (Denmark)

    Nielsen, Anne Maj; Kolmos, Marie

    to know whether the researcher and the child share understandings of verbal articulations. A similar challenge counts for phenomena and experiences that may be difficult to describe and articulate in verbal language such as sensory and body experiences and diverse experiences of awareness, attention....... In both studies the mutual material references offer new opportunities for the children’s participation, articulation and re-experiencing in the interview situations....

  6. Mint3 in bone marrow-derived cells promotes lung metastasis in breast cancer model mice.

    Science.gov (United States)

    Hara, Toshiro; Murakami, Yoshinori; Seiki, Motoharu; Sakamoto, Takeharu

    2017-08-26

    Breast cancer is one of the most common cancers in women in the world. Although breast cancer is well treatable at the early stage, patients with distant metastases show a poor prognosis. Data from recent studies using transplantation models indicate that Mint3/APBA3 might promote breast cancer malignancy. However, whether Mint3 indeed contributes to tumor development, progression, or metastasis in vivo remains unclear. To address this, here we examined whether Mint3 depletion affects tumor malignancy in MMTV-PyMT breast cancer model mice. In MMTV-PyMT mice, Mint3 depletion did not affect tumor onset and tumor growth, but attenuated lung metastases. Experimental lung metastasis of breast cancer Met-1 cells derived from MMTV-PyMT mice also decreased in Mint3-depleted mice, indicating that host Mint3 expression affected lung metastasis of MMTV-PyMT-derived breast cancer cells. Further bone marrow transplant experiments revealed that Mint3 in bone marrow-derived cells promoted lung metastasis in MMTV-PyMT mice. Thus, targeting Mint3 in bone marrow-derived cells might be a good strategy for preventing metastasis and improving the prognosis of breast cancer patients. Copyright © 2017 Elsevier Inc. All rights reserved.

  7. Experimental and Modeling Study of Kinetics for Methane Hydrate Formation with Tetrahydrofuran as Promoter

    Institute of Scientific and Technical Information of China (English)

    Ning Zhengfu; Zhang Shixi; Zhang Qin; Zhen Shuangyi; Chen Guangjin

    2007-01-01

    The kinetics behavior of methane hydrate formation in the presence of tetrahydrofuran (THF) as promoter was studied. A set of experimental equipment was designed and constructed. A series of kinetics data for the formation of methane hydrate in the presence of THF were measured with the isochoric method. The influences of temperature,pressure and liquid flow rate on the methane consumption rate were studied respectively. Based on the Chen-Guo hydrate formation mechanism,a kinetics model for the formation of methane hydrate in the presence of THF by using the dimensionless Gibbs free energy difference of quasi-chemical reaction of basic hydrate formation,,as the driving force was proposed. The model was used to calculate the rate of methane consumption and it was shown that the calculated results were in good agreement with the experimental results.

  8. Does trust promote more teamwork? Modeling online game players' teamwork using team experience as a moderator.

    Science.gov (United States)

    Lee, Chun-Chia; Chang, Jen-Wei

    2013-11-01

    The need for teamwork has grown significantly in today's organizations. Especially for online game communities, teamwork is an important means of online game players' engagement. This study aims to investigate the impacts of trust on players' teamwork with affective commitment and normative commitment as mediators. Furthermore, this research includes team experience as a moderator to compare the difference between different player groups. A model was proposed and tested on 296 online game players' data using structural equation modeling. Findings revealed that team experience moderated the relationship between trust and teamwork. The results indicated that trust promotes more teamwork only for players with high experience through affective commitment than those who with low experience. Implications of the findings are discussed.

  9. Evaluation of relationship between feeding reflexes and articulation in spastic cerebral palsy

    Directory of Open Access Journals (Sweden)

    M.R. Hadian

    2006-07-01

    Full Text Available Background: Cerebral palsy is the term used to describe a movement disorder though to be the result of nonprogressive brain damage. Due to damage to CNS, it is associated with articulation disorder and abnormal feeding reflex. Lack of oral function control and coordination following feeding reflex disorders. Articulation disorders are seen in most of the cerebral palsied patients.This research aimed to determine the relationship between feeding reflexes and articulation in cerebral palsy (spasticchildren. Methods: This study was cross sectionally carried out on 52 children with cerebral palsy, 5 to 10 yrs old, in rehabilitation centers and private clinics. The information related to feeding reflexes was collected through direct observation of patient and evaluation of sound articulation through phonetic information test. Results: Statistical analysis carried out by SPSS and chi-square and fisher exact tests. Abnomal chewing and tongue reflex are more prevalent than other feeding reflexes.The relationship between lip reflex and articulation of p/m/r/y/f/č and chewing reflex with articulation of/z/š/ is meaningful. The relationship between biting reflex with articulation of /z/j/l/š/ is meaningful. The relationship between tongue reflex and rooting reflex with articulation of sound is not meaningful. Conclusion: With regard to the result of this research, it can be suggested that in children with cerebral palsy following feeding reflex disorders, abnormal posture during speech occurs that could have effect on articulation.

  10. Measurement uncertainty analysis on laser tracker combined with articulated CMM

    Science.gov (United States)

    Zhao, Hui-ning; Yu, Lian-dong; Du, Yun; Zhang, Hai-yan

    2013-10-01

    The combined measurement technology plays an increasingly important role in the digitalized assembly. This paper introduces a combined measurement system consists of a Laser tracker and a FACMM,with the applications in the inspection of the position of the inner parts in a large-scale device. When these measurement instruments are combined, the resulting coordinate data set contains uncertainties that are a function of the base data sets and complex interactions between the measurement sets. Combined with the characteristics of Laser Tracker and Flexible Articulated Coordinate Measuring Machine (FACMM),Monte-Claro simulation mothed is employed in the uncertainty evaluation of combined measurement systems. A case study is given to demonstrate the practical applications of this research.

  11. Speech articulator measurements using low power EM-wave sensors

    Energy Technology Data Exchange (ETDEWEB)

    Holzrichter, J.F.; Burnett, G.C.; Ng, L.C. [Lawrence Livermore National Laboratory, P.O. Box 808, Livermore, California 94551 (United States); Lea, W.A. [Speech Science Institute, P.O. Box 240428, Apple Valley, Minnesota 55124 (United States)

    1998-01-01

    Very low power electromagnetic (EM) wave sensors are being used to measure speech articulator motions as speech is produced. Glottal tissue oscillations, jaw, tongue, soft palate, and other organs have been measured. Previously, microwave imaging (e.g., using radar sensors) appears not to have been considered for such monitoring. Glottal tissue movements detected by radar sensors correlate well with those obtained by established laboratory techniques, and have been used to estimate a voiced excitation function for speech processing applications. The noninvasive access, coupled with the small size, low power, and high resolution of these new sensors, permit promising research and development applications in speech production, communication disorders, speech recognition and related topics. {copyright} {ital 1998 Acoustical Society of America.}

  12. Sensory Integration with Articulated Motion on a Humanoid Robot

    Directory of Open Access Journals (Sweden)

    J. Rojas

    2005-01-01

    Full Text Available This paper describes the integration of articulated motion with auditory and visual sensory information that enables a humanoid robot to achieve certain reflex actions that mimic those of people. Reflexes such as reach-and-grasp behavior enables the robot to learn, through experience, its own state and that of the world. A humanoid robot with binaural audio input, stereo vision, and pneumatic arms and hands exhibited tightly coupled sensory-motor behaviors in four different demonstrations. The complexity of successive demonstrations was increased to show that the reflexive sensory-motor behaviors combine to perform increasingly complex tasks. The humanoid robot executed these tasks effectively and established the groundwork for the further development of hardware and software systems, sensory-motor vector-space representations, and coupling with higher-level cognition.

  13. African American English: Dialect Mistaken As an Articulation Disorder

    Directory of Open Access Journals (Sweden)

    Wilson, Sade

    2012-01-01

    Full Text Available The purpose of this literature review is to discuss the reasons speech-language pathologists often misdiagnose children using AAE as having articulation and phonological disorders. In my literature review, I will discuss three ruling explanations for why this problem occurs. The most common reason for this misdiagnosis is that speech-language pathologists (SLPs are unfamiliar with AAE acquisition and its phonological features. The second is that SLPs administer norm-referenced standardized tests that are culturally biased, which unfairly contributes to these errors. Finally, SLPs often do not realize that AAE speaking children are, in a way, learning a second dialect ¾ Standard American English ¾ in school. Each of these practices delivers inaccurate information about the child, placing the SLPs and their clients at a disadvantage. I will provide recommendations and suggestions for SLPs. My argument is that changes can, and should, be made.

  14. Palatalization in English: An Articulation Problem for Turkish Teacher Trainees

    Directory of Open Access Journals (Sweden)

    Prof. Dr. Mehmet Demirezen

    2005-04-01

    Full Text Available In the field of teacher training, there is a scarcity of teaching pronunciation teachingmethodology to cure the fossilized mistakes of teacher trainees and foreign language teacherson-the-job. A case study pertaining to this situation is handled for the first time in this articleunder the title of “Audio-articulation Method” (Demirezen, 2003; Hişmanoğlu, 2004. Thismethod takes up a fossilized mistake of teacher trainees or teachers on-the-job in fifty minutesand brings in pronunciation correction by using tongue-twisters, idioms, proverbs, and thelike. Thus, it cures the fossilized mistake to a grater extent by creating a higher awareness andimproving communicative fluency. This method through task-based point of view removesthe related fossilized mistake and brings in pronunciation betterment to the teacher traineesand the teachers on-the-job.

  15. Articulations of Health and Poverty Among Women on WIC.

    Science.gov (United States)

    Yehya, Nadine A; Dutta, Mohan J

    2015-01-01

    With the global financial meltdown, the crisis of poverty has deepened in communities across the United States. This essay reports results from a culture-centered project on fostering spaces for listening to the voices of the poor in CrossRoads County, Indiana. It highlights the intersections of health and poverty as they emerge from the narratives of mothers utilizing the Supplemental Nutrition Program for Women, Infants, and Children (WIC). Depression, humiliation, and inaccessibility to health care and healthy living outline the struggles of women as they negotiate their access to health. The articulations of agency are situated around competing cultural narratives that, on the one hand, draw on the threads of individual responsibility which resonate through mainstream discourses of poverty in the United States and, on the other hand, interrogate the structural erasure of the basic capacities of health.

  16. Visual servo simulation of EAST articulated maintenance arm robot

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Yang, E-mail: yangyang@ipp.ac.cn [Institute of Plasma Physics, Chinese Academy of Sciences, 350 Shushanhu Rd, Hefei, Anhui (China); Song, Yuntao; Pan, Hongtao; Cheng, Yong; Feng, Hansheng [Institute of Plasma Physics, Chinese Academy of Sciences, 350 Shushanhu Rd, Hefei, Anhui (China); Wu, Huapeng [Lappeenranta University of Technology, Skinnarilankatu 34, Lappeenranta (Finland)

    2016-03-15

    For the inspection and light-duty maintenance of the vacuum vessel in the EAST tokamak, a serial robot arm, called EAST articulated maintenance arm, is developed. Due to the 9-m-long cantilever arm, the large flexibility of the EAMA robot introduces a problem in the accurate positioning. This article presents an autonomous robot control to cope with the robot positioning problem, which is a visual servo approach in context of tile grasping for the EAMA robot. In the experiments, the proposed method was implemented in a simulation environment to position and track a target graphite tile with the EAMA robot. As a result, the proposed visual control scheme can successfully drive the EAMA robot to approach and track the target tile until the robot reaches the desired position. Furthermore, the functionality of the simulation software presented in this paper is proved to be suitable for the development of the robotic and computer vision application.

  17. Testing Models: A Key Aspect to Promote Teaching Activities Related to Models and Modelling in Biology Lessons?

    Science.gov (United States)

    Krell, Moritz; Krüger, Dirk

    2016-01-01

    This study investigated biology teachers' (N = 148) understanding of models and modelling (MoMo), their model-related teaching activities and relations between the two. A framework which distinguishes five aspects of MoMo in science ("nature of models," "multiple models," "purpose of models," "testing…

  18. Testing Models: A Key Aspect to Promote Teaching Activities Related to Models and Modelling in Biology Lessons?

    Science.gov (United States)

    Krell, Moritz; Krüger, Dirk

    2016-01-01

    This study investigated biology teachers' (N = 148) understanding of models and modelling (MoMo), their model-related teaching activities and relations between the two. A framework which distinguishes five aspects of MoMo in science ("nature of models," "multiple models," "purpose of models," "testing…

  19. On Promoting the Construction of Model Province of National Rural Informationization in Hubei

    Directory of Open Access Journals (Sweden)

    Pengfei Zhang

    2014-04-01

    Full Text Available The construction of model province of national rural informationization, which needs more departments jointly and participants, is a systematic, socialized major project. Hubei provincial government, standing in the angle of planning the province's economic and social development as a whole, proposes the “one Yuan multi-level” development strategy and it has laid a solid foundation to make Hubei province become the construction pilot provinces of “model province of national rural informationization”. In the construction of model province of rural informationization, the open and inclusive concept is of great significance to realize national long-term goals and make the rural information service sustained and long efficient. At the same time, each department and each participation main body coordinate with each other, which realize the integration of rural information service resources and prevent rural information service from redundant and inefficient investment. Therefore, in the construction of model province of national rural informationization, Hubei province need to uphold the open and inclusive concept, further emancipate the mind, and complement each other. It should strengthen organizational leadership, complete the top planning and design, strengthen the department coordination, innovate information services operating mechanism, strengthen integration of information resources and integrated application of service platform, strengthen the system construction and examination management, strengthen the propaganda guidance, and further promote each work of model province carried out smoothly and orderly.

  20. Building a pseudo-atomic model of the anaphase-promoting complex

    Energy Technology Data Exchange (ETDEWEB)

    Kulkarni, Kiran; Zhang, Ziguo; Chang, Leifu; Yang, Jing; Fonseca, Paula C. A. da; Barford, David, E-mail: david.barford@icr.ac.uk [Institute of Cancer Research, Chester Beatty Laboratories, 237 Fulham Road, London SW3 6JB (United Kingdom)

    2013-11-01

    This article describes an example of molecular replacement in which atomic models are used to interpret electron-density maps determined using single-particle electron-microscopy data. The anaphase-promoting complex (APC/C) is a large E3 ubiquitin ligase that regulates progression through specific stages of the cell cycle by coordinating the ubiquitin-dependent degradation of cell-cycle regulatory proteins. Depending on the species, the active form of the APC/C consists of 14–15 different proteins that assemble into a 20-subunit complex with a mass of approximately 1.3 MDa. A hybrid approach of single-particle electron microscopy and protein crystallography of individual APC/C subunits has been applied to generate pseudo-atomic models of various functional states of the complex. Three approaches for assigning regions of the EM-derived APC/C density map to specific APC/C subunits are described. This information was used to dock atomic models of APC/C subunits, determined either by protein crystallography or homology modelling, to specific regions of the APC/C EM map, allowing the generation of a pseudo-atomic model corresponding to 80% of the entire complex.

  1. A model for promoting physical activity among rural South African adolescent girls

    Directory of Open Access Journals (Sweden)

    John Kinsman

    2015-12-01

    Full Text Available Background: In South Africa, the expanding epidemic of non-communicable diseases is partly fuelled by high levels of physical inactivity and sedentary behaviour. Women especially are at high risk, and interventions promoting physical activity are urgently needed for girls in their adolescence, as this is the time when many girls adopt unhealthy lifestyles. Objective: This qualitative study aimed to identify and describe facilitating factors and barriers that are associated with physical activity among adolescent girls in rural, north-eastern South Africa and, based on these, to develop a model for promoting leisure-time physical activity within this population. Design: The study was conducted in and around three secondary schools. Six focus group discussions were conducted with adolescent girls from the schools, and seven qualitative interviews were held with sports teachers and youth leaders. The data were subjected to thematic analysis. Results: Seven thematic areas were identified, each of which was associated with the girls’ self-reported levels of physical activity. The thematic areas are 1 poverty, 2 body image ideals, 3 gender, 4 parents and home life, 5 demographic factors, 6 perceived health effects of physical activity, and 7 human and infrastructural resources. More barriers to physical activity were reported than facilitating factors. Conclusions: Analysis of the barriers found in the different themes indicated potential remedial actions that could be taken, and these were synthesised into a model for promoting physical activity among South African adolescent girls in resource-poor environments. The model presents a series of action points, seen both from the ‘supply-side’ perspective (such as the provision of resources and training for the individuals, schools, and organisations which facilitate the activities and from the ‘demand-side’ perspective (such as the development of empowering messages about body image for

  2. A model for promoting physical activity among rural South African adolescent girls

    Science.gov (United States)

    Kinsman, John; Norris, Shane A.; Kahn, Kathleen; Twine, Rhian; Riggle, Kari; Edin, Kerstin; Mathebula, Jennifer; Ngobeni, Sizzy; Monareng, Nester; Micklesfield, Lisa K.

    2015-01-01

    Background In South Africa, the expanding epidemic of non-communicable diseases is partly fuelled by high levels of physical inactivity and sedentary behaviour. Women especially are at high risk, and interventions promoting physical activity are urgently needed for girls in their adolescence, as this is the time when many girls adopt unhealthy lifestyles. Objective This qualitative study aimed to identify and describe facilitating factors and barriers that are associated with physical activity among adolescent girls in rural, north-eastern South Africa and, based on these, to develop a model for promoting leisure-time physical activity within this population. Design The study was conducted in and around three secondary schools. Six focus group discussions were conducted with adolescent girls from the schools, and seven qualitative interviews were held with sports teachers and youth leaders. The data were subjected to thematic analysis. Results Seven thematic areas were identified, each of which was associated with the girls’ self-reported levels of physical activity. The thematic areas are 1) poverty, 2) body image ideals, 3) gender, 4) parents and home life, 5) demographic factors, 6) perceived health effects of physical activity, and 7) human and infrastructural resources. More barriers to physical activity were reported than facilitating factors. Conclusions Analysis of the barriers found in the different themes indicated potential remedial actions that could be taken, and these were synthesised into a model for promoting physical activity among South African adolescent girls in resource-poor environments. The model presents a series of action points, seen both from the ‘supply-side’ perspective (such as the provision of resources and training for the individuals, schools, and organisations which facilitate the activities) and from the ‘demand-side’ perspective (such as the development of empowering messages about body image for teenage girls, and

  3. The complete mitochondrial genome of Articulate Brachiopod Terebratal ia transversa

    Energy Technology Data Exchange (ETDEWEB)

    Helfenbein, Kevin G.; Brown, Wesley M.; Boore, Jeffrey L.

    2001-07-01

    We have sequenced the complete mitochondrial DNA (mtDNA) of the articulate brachiopod Terebratalia transversa. The circular genome is 14,291 bp in size, relatively small compared to other published metazoan mtDNAs. The 37 genes commonly found in animal mtDNA are present; the size decrease is due to the truncation of several tRNA, rRNA, and protein genes, to some nucleotide overlaps, and to a paucity of non-coding nucleotides. Although the gene arrangement differs radically from those reported for other metazoans, some gene junctions are shared with two other articulate brachiopods, Laqueus rubellus and Terebratulina retusa. All genes in the T. transversa mtDNA, unlike those in most metazoan mtDNAs reported, are encoded by the same strand. The A+T content (59.1 percent) is low for a metazoan mtDNA, and there is a high propensity for homopolymer runs and a strong base-compositional strand bias. The coding strand is quite G+T-rich, a skew that is shared by the confamilial (laqueid) specie s L. rubellus, but opposite to that found in T. retusa, a cancellothyridid. These compositional skews are strongly reflected in the codon usage patterns and the amino acid compositions of the mitochondrial proteins, with markedly different usage observed between T. retusa and the two laqueids. This observation, plus the similarity of the laqueid non-coding regions to the reverse complement of the non-coding region of the cancellothyridid, suggest that an inversion that resulted in a reversal in the direction of first-strand replication has occurred in one of the two lineages. In addition to the presence of one non-coding region in T. transversa that is comparable to those in the other brachiopod mtDNAs, there are two others with the potential to form secondary structures; one or both of these may be involved in the process of transcript cleavage.

  4. Evaluation of an e-PBL model to promote individual reasoning.

    Science.gov (United States)

    Kim, Kyong-Jee; Kee, Changwon

    2013-01-01

    Medical educators should promote the development of student clinical reasoning toward independence in clinical settings. The objective of this study was to evaluate an online problem-based learning (e-PBL) model designed to promote student individual reasoning in supplement to traditional PBL. Twelve e-PBL modules were added to the fully problem-based curriculum for Year 2 at Sungkyunkwan University School of Medicine (SKKUSOM). In this e-PBL, students worked on the problems individually in an online setting, followed by face-to-face discussions in a colloquium. The cases were presented using interactive multimedia to enhance the authenticity of the case and stimulate student interest in learning. A formative evaluation study was conducted to determine student satisfaction with e-PBL and its effectiveness as perceived by the students using both quantitative and qualitative methods. A cohort of Year 2 students at SKKUSOM (n = 38) took part in this study. Students perceived e-PBL significantly more positively after they had taken a module in terms of its ability to foster problem-solving skills and its ability to allow them to learn in ways suited to individual learning styles. Additionally, student survey and interview revealed that a vast majority of students were satisfied with the overall learning process in e-PBL and perceived it positively in fostering knowledge acquisition and clinical reasoning. Moreover, students found the cases realistic and engaging. The results show the potential of e-PBL to enhance traditional PBL by promoting the development of individual reasoning in a flexible online-learning environment and offering cases in an interactive multimedia format, which warrants further investigation into its impact on student learning outcomes.

  5. Computational modeling identifies key gene regulatory interactions underlying phenobarbital-mediated tumor promotion

    Science.gov (United States)

    Luisier, Raphaëlle; Unterberger, Elif B.; Goodman, Jay I.; Schwarz, Michael; Moggs, Jonathan; Terranova, Rémi; van Nimwegen, Erik

    2014-01-01

    Gene regulatory interactions underlying the early stages of non-genotoxic carcinogenesis are poorly understood. Here, we have identified key candidate regulators of phenobarbital (PB)-mediated mouse liver tumorigenesis, a well-characterized model of non-genotoxic carcinogenesis, by applying a new computational modeling approach to a comprehensive collection of in vivo gene expression studies. We have combined our previously developed motif activity response analysis (MARA), which models gene expression patterns in terms of computationally predicted transcription factor binding sites with singular value decomposition (SVD) of the inferred motif activities, to disentangle the roles that different transcriptional regulators play in specific biological pathways of tumor promotion. Furthermore, transgenic mouse models enabled us to identify which of these regulatory activities was downstream of constitutive androstane receptor and β-catenin signaling, both crucial components of PB-mediated liver tumorigenesis. We propose novel roles for E2F and ZFP161 in PB-mediated hepatocyte proliferation and suggest that PB-mediated suppression of ESR1 activity contributes to the development of a tumor-prone environment. Our study shows that combining MARA with SVD allows for automated identification of independent transcription regulatory programs within a complex in vivo tissue environment and provides novel mechanistic insights into PB-mediated hepatocarcinogenesis. PMID:24464994

  6. Building a pseudo-atomic model of the anaphase-promoting complex.

    Science.gov (United States)

    Kulkarni, Kiran; Zhang, Ziguo; Chang, Leifu; Yang, Jing; da Fonseca, Paula C A; Barford, David

    2013-11-01

    The anaphase-promoting complex (APC/C) is a large E3 ubiquitin ligase that regulates progression through specific stages of the cell cycle by coordinating the ubiquitin-dependent degradation of cell-cycle regulatory proteins. Depending on the species, the active form of the APC/C consists of 14-15 different proteins that assemble into a 20-subunit complex with a mass of approximately 1.3 MDa. A hybrid approach of single-particle electron microscopy and protein crystallography of individual APC/C subunits has been applied to generate pseudo-atomic models of various functional states of the complex. Three approaches for assigning regions of the EM-derived APC/C density map to specific APC/C subunits are described. This information was used to dock atomic models of APC/C subunits, determined either by protein crystallography or homology modelling, to specific regions of the APC/C EM map, allowing the generation of a pseudo-atomic model corresponding to 80% of the entire complex.

  7. Partner choice promotes cooperation: the two faces of testing with agent-based models.

    Science.gov (United States)

    Campennì, Marco; Schino, Gabriele

    2014-03-07

    Reciprocity is one of the most debated among the mechanisms that have been proposed to explain the evolution of cooperation. While a distinction can be made between two general processes that can underlie reciprocation (within-pair temporal relations between cooperative events, and partner choice based on benefits received), theoretical modelling has concentrated on the former, while the latter has been often neglected. We developed a set of agent-based models in which agents adopted a strategy of obligate cooperation and partner choice based on benefits received. Our models tested the ability of partner choice both to reproduce significant emergent features of cooperation in group living animals and to promote the evolution of cooperation. Populations formed by agents adopting a strategy of obligate cooperation and partner choice based on benefits received showed differentiated "social relationships" and a positive correlation between cooperation given and received, two common phenomena in animal cooperation. When selection across multiple generations was added to the model, agents adopting a strategy of partner choice based on benefits received outperformed selfish agents that did not cooperate. Our results suggest partner choice is a significant aspect of cooperation and provides a possible mechanism for its evolution.

  8. Avaliação radiográfica e de função de vôo após fixação de osteotomias distais do úmero em pombas (Columba livia, com modelo de fixador externo articulado Radiologic and flight function evaluation after fixation of distal humeral osteotomies in pigeons, with model of articulated external fixator

    Directory of Open Access Journals (Sweden)

    Vanessa C.M. Ferraz

    2008-08-01

    viabilidade de músculos e tendões, e assim, garantindo a capacidade de vôo das aves tratadas, sendo um método adequado para a reparação de fraturas distais de úmero em aves quando se pretende a reabilitação destes animais.The treatment of distal humeral fractures in birds is very difficult, technically and for consolidation and maintenance of normal function of the wing, because theses bones are pneumatic, and its cortices very thin. The ankylosis of the humerus-radius-ulnar joint with external fixator is unviable for birds intended for rehabilitation and release. In all animals, the experimental fixator was placed over the humerus, with its articulation over the humerus-radial-ulnar joint e the extension of the fixator was placed over the ulna. The animals were divided in two groups: bilateral surgeries with ankylosis in one wing (static wing and maintenance of the joint function in the other (dynamic wing (Group 1, and unilateral surgery, with maintenance of the joint function (dynamic wing (Group 2. The bonny callus was evaluated with radiographs: post-surgical, at 3, 6 and 9 weeks. The birds in Group 2 were evaluated as of their flight abilities between 11 and 15 weeks after surgery. The wing amplitude and humeral length was evaluated in all animals, after euthanasia. At 6 weeks, all the animals in Group 2, that underwent unilateral surgery, without ankylosis, and four animals in Group 1, that underwent bilateral surgeries: ankylosis of one elbow (static wing and not of the other (dynamic wing, presented radiographic and clinical consolidation of the fractures. Two animals in Group 1 only presented consolidation of the dynamic wing at 9 weeks and of the static wing at 12 weeks. All the animals in Group 2 presented adequate flight capacity, in at least 13 weeks after surgery. There are few published papers on bird osteosynthesis, and therefore we studied the use of articulated external fixator for the stabilization of distal humeral fractures, avoiding ankylosis

  9. Diabetes empowerment related to Pender's Health Promotion Model: a meta-synthesis.

    Science.gov (United States)

    Ho, Agnes Yin Kwan; Berggren, Ingela; Dahlborg-Lyckhage, Elisabeth

    2010-06-01

    Diabetes self-management is a challenge for both clients and health-care professionals. Empowerment plays a vital role in helping clients to achieve successful self-management. This study adopted a meta-ethnographic approach. Nine qualitative studies were synthesized in order to contribute to a deeper understanding of what clients perceive as being important in an effective empowerment strategy for diabetes self-management. Four central metaphors that influenced empowerment were identified: trust in nurses' competence and awareness, striving for control, a desire to share experiences, and nurses' attitudes and ability to personalize. The lines-of-argument synthesis suggested the need for an evaluation system to appraise clients' diabetes knowledge, health beliefs, and negative emotions, as well as the outcome of interventions. Based on Pender's Health Promotion Model, this study emphasizes the fact that health-care professionals need to understand and address modifiable behavior-specific variables. The study suggests that an effective empowerment strategy would be to use activity-related affect, as well as interpersonal and situational influences, as a means of facilitating and enhancing clients' health-promoting behaviors.

  10. C-peptide promotes lesion development in a mouse model of arteriosclerosis.

    Science.gov (United States)

    Vasic, Dusica; Marx, Nikolaus; Sukhova, Galina; Bach, Helga; Durst, Renate; Grüb, Miriam; Hausauer, Angelina; Hombach, Vinzenz; Rottbauer, Wolfgang; Walcher, Daniel

    2012-04-01

    Patients with insulin resistance and early type 2 diabetes exhibit an increased propensity to develop a diffuse and extensive pattern of arteriosclerosis. Typically, these patients show elevated serum levels of the proinsulin cleavage product C-peptide and immunohistochemical data from our group revealed C-peptide deposition in early lesions of these individuals. Moreover, in vitro studies suggest that C-peptide could promote atherogenesis. This study examined whether C-peptide promotes vascular inflammation and lesion development in a mouse model of arteriosclerosis. ApoE-deficient mice on a high fat diet were treated with C-peptide or control injections for 12 weeks and the effect on lesion size and plaque composition was analysed. C-peptide treatment significantly increased C-peptide blood levels by 4.8-fold without having an effect on glucose or insulin levels, nor on the lipid profile. In these mice, C-peptide deposition in atherosclerotic plaques was significantly increased compared with controls. Moreover, lesions of C-peptide-treated mice contained significantly more macrophages (1.6 ± 0.3% versus 0.7 ± 0.2% positive area; P arteriosclerosis support the hypothesis that C-peptide may have an active role in atherogenesis in patients with diabetes and insulin resistance.

  11. Antibiotics Smart Use: a workable model for promoting the rational use of medicines in Thailand.

    Science.gov (United States)

    Sumpradit, Nithima; Chongtrakul, Pisonthi; Anuwong, Kunyada; Pumtong, Somying; Kongsomboon, Kedsenee; Butdeemee, Parichart; Khonglormyati, Jurairat; Chomyong, Santi; Tongyoung, Parnuchote; Losiriwat, Suraphol; Seesuk, Piyanooch; Suwanwaree, Pongthep; Tangcharoensathien, Viroj

    2012-12-01

    The Antibiotics Smart Use (ASU) programme was introduced in Thailand as a model to promote the rational use of medicines, starting with antibiotics. The programme's first phase consisted of assessing interventions intended to change prescribing practices; the second phase examined the feasibility of programme scale-up. Currently the programme is in its third phase, which centres on sustainability. This paper describes the concept behind ASU, the programme's functional modalities, the development of its conceptual framework and the implementation of its first and second phases. To change antibiotic prescription practices, multifaceted interventions at the individual and organizational levels were implemented; to maintain behaviour change and scale up the programme, interventions at the network and policy levels were used. The National Health Security Office has adopted ASU as a pay-for-performance criterion, a major achievement that has led to the programme's expansion nationwide. Despite limited resources, programme scale-up and sustainability have been facilitated by the promotion of local ownership and mutual recognition, which have generated pride and commitment. ASU is clearly a workable entry point for efforts to rationalize the use of medicines in Thailand. Its long-term sustainability will require continued local commitment and political support, effective auditing and integration of ASU into routine systems with appropriate financial incentives.

  12. Promoting the development of professional identity of gerontologists: an academic/experiential learning model.

    Science.gov (United States)

    Gendron, Tracey L; Myers, Barbara J; Pelco, Lynn E; Welleford, E Ayn

    2013-01-01

    Graduate education in gerontology has an essential role in providing the foundational knowledge required to work with a diverse aging population. It can also play an essential role in promoting best-practice approaches for the development of professional identity as a gerontologist. The primary goal of this study was to determine what factors predict the professional identity and career path of gerontologists. In addition, the study explored how experiential learning influenced professional identity for newcomers to the field and for those experienced in an aging-related field ("professional incumbents"). Graduates (N = 146) of Association for Gerontology in Higher Education-affiliated graduate programs participated. Professional identity as a gerontologist was predicted by length of time in the field, age, satisfaction with coworkers, and satisfaction with opportunities for advancement. Experiential learning contributed to professional identity in important but different ways for newcomers to the field and for professional incumbents. The inclusion of an academic/experiential learning model within graduate gerontology programs promotes the development of professional identity and career path for all graduate students.

  13. The PHLAME (Promoting Healthy Lifestyles: Alternative Models' Effects) firefighter study: testing mediating mechanisms.

    Science.gov (United States)

    Ranby, Krista W; MacKinnon, David P; Fairchild, Amanda J; Elliot, Diane L; Kuehl, Kerry S; Goldberg, Linn

    2011-10-01

    This paper examines the mechanisms by which PHLAME (Promoting Healthy Lifestyles: Alternative Models' Effects), a health promotion intervention, improved healthy eating and exercise behavior among firefighters, a population at high risk for health problems due to occupational hazards. In a randomized trial, 397 firefighters participated in either the PHLAME team intervention with their work shift or a control condition. Intervention sessions taught benefits of a healthy diet and regular exercise, and sought to improve social norms and social support from coworkers for healthy behavior. At posttest, team intervention participants had increased their fruit and vegetable consumption as compared to control participants. An increase in knowledge of fruit and vegetable benefits and improved dietary coworker norms partially mediated these effects. Exercise habits and VO2 max were related to targeted mediators but were not significantly changed by the team intervention. Partial support was found for both the action and conceptual theories underlying the intervention. Our findings illustrate how an effective program's process can be deconstructed to understand the underpinnings of behavior change and refine interventions. Further, fire stations may improve the health of firefighters by emphasizing the benefits of healthy diet and exercise behaviors while also encouraging behavior change by coworkers as a whole. (PsycINFO Database Record (c) 2011 APA, all rights reserved).

  14. Accuracy of two face-bow/semi-adjustable articulator systems in transferring the maxillary occlusal cant

    Directory of Open Access Journals (Sweden)

    Nazia Nazir

    2012-01-01

    Full Text Available Context: The precision of an arbitrary face-bow in accurately transferring the orientation of the maxillary cast to the articulator has been questioned because the maxillary cast is mounted in relation to arbitrary measurements and anatomic landmarks that vary among individuals. Aim: This study was intended to evaluate the sagittal inclination of mounted maxillary casts on two semi-adjustable articulator/face-bow systems in comparison to the occlusal cant on lateral cephalograms. Materials and Methods: Maxillary casts were mounted on the Hanau and Girrbach semi-adjustable articulators following face-bow transfer with their respective face-bows. The sagittal inclination of these casts was measured in relation to the fixed horizontal reference plane using physical measurements. Occlusal cant was measured on lateral cephalograms. SPSS software (version 11.0, Chicago, IL, USA was used for statistical analysis. Repeated measures analysis of variance and Tukey′s tests were used to evaluate the results (P < 0.05. Results: Comparison of the occlusal cant on the articulators and cephalogram revealed statistically significant differences. Occlusal plane was steeper on Girrbach Artex articulator in comparison to the Hanau articulator. Conclusion: Within the limitations of this study, it was found that the sagittal inclination of the mounted maxillary cast achieved with Hanau articulator was closer to the cephalometric occlusal cant as compared to that of the Girrbach articulator. Among the two articulators and face-bow systems, the steepness of sagittal inclination was greater on Girrbach semi-adjustable articulator. Different face-bow/articulator systems could result in different orientation of the maxillary cast, resulting in variation in stability, cuspal inclines and cuspal heights.

  15. Method for analyzing articulated torques of heavy-duty six-legged robot

    Science.gov (United States)

    Zhuang, Hongchao; Gao, Haibo; Ding, Liang; Liu, Zhen; Deng, Zongquan

    2013-07-01

    The accuracy of an articulated torque analysis influences the comprehensive performances of heavy-duty multi-legged robots. Currently, the extremal estimation method and some complex methods are employed to calculate the articulated torques, which results in a large safety margin or a large number of calculations. To quickly obtain accurate articulated torques, an analysis method for the articulated torque is presented for an electrically driven heavy-duty six-legged robot. First, the rearmost leg that experiences the maximum normal contact force is confirmed when the robot transits a slope. Based on the ant-type and crab-type tripod gaits, the formulas of classical mechanics and MATLAB software are employed to theoretically analyze the relevant static torques of the joints. With the changes in the joint angles for the abductor joint, hip joint, and knee joint, variable tendency charts and extreme curves are obtained for the static articulated torques. Meanwhile, the maximum static articulated torques and the corresponding poses of the robot are also obtained. According to the poses of the robot under the maximum static articulated torques, ADAMS software is used to carry out a static simulation analysis. Based on the relevant simulation curves of the articulated torques, the maximum static articulated torques are acquired. A comparative analysis of the maximum static articulated torques shows that the theoretical calculation values are higher than the static simulation values, and the maximum error value is approximately 10%. The proposed method lays a foundation for quickly determining accurate articulated torques to develop heavy-duty six-legged robots.

  16. Informal work and formal plans: articulating the active role of patients in cancer trajectories

    DEFF Research Database (Denmark)

    Dalsted, Rikke Juul; Hølge-Hazelton, Bibi; Brostrøm Kousgaard, Marius

    2012-01-01

    Introduction: Formal pathway models outline that patients should receive information in order to experience a coherent journey but do not describe an active role for patients or their relatives. The aim of this is paper is to articulate and discuss the active role of patients during their cancer...... trajectories. Methods and theory: An in-depth case study of patient trajectories at a Danish hospital and surrounding municipality using individual interviews with patients. Theory about trajectory and work by Strauss was included. Results: Patients continuously took initiatives to organize their treatment...... and care. They initiated processes in the trajectories, and acquired information, which they used to form their trajectories. Patients presented problems to the healthcare professionals in order to get proper help when needed. Discussion: Work done by patients was invisible and not perceived as work...

  17. "A memorable consultation": writing reflective accounts articulates students' learning in general practice.

    Science.gov (United States)

    Svenberg, Kristian; Wahlqvist, Mats; Mattsson, Bengt

    2007-06-01

    To explore and analyse students' learning experiences of a memorable consultation during a final-year attachment in general practice. After a two-week primary care attachment in the undergraduate curriculum, students were invited to write a reflective account of a memorable consultation. A total of 52 reflective accounts were read and processed according to qualitative content analysis. Credibility of the analysis was validated by two co-authors reading the descriptions separately and trustworthiness was tested at local seminars. Three main themes emerged. In "The person beyond symptoms" the students recognize the individual properties of a consultation. "Facing complexity" mirrors awareness of changing tracks in problem-solving and strategies of handling unclear conditions. "In search of a professional role" reflects the interest in role modelling and the relation to the supervisor. Involving students in writing reflective accounts appears to stimulate them to articulate practice experiences of the consultation.

  18. A case study in nonlinear dynamics and control of articulated spacecraft: The Space Station Freedom with a mobile remote manipulator system

    Science.gov (United States)

    Bennett, William H.; Kwatny, Harry G.; Lavigna, Chris; Blankenship, Gilmer

    1994-06-01

    The following topics are discussed: (1) modeling of articulated spacecraft as multi-flex-body systems; (2) nonlinear attitude control by adaptive partial feedback linearizing (PFL) control; (3) attitude dynamics and control for SSF/MRMS; and (4) performance analysis results for attitude control of SSF/MRMS.

  19. Modelling of tetrahydrofuran promoted gas hydrate systems for carbon dioxide capture processes

    DEFF Research Database (Denmark)

    Herslund, Peter Jørgensen; Thomsen, Kaj; Abildskov, Jens

    2014-01-01

    accurate descriptions of both fluid- and hydrate phase equilibria in the studied system and its subsystems. The developed model is applied to simulate two simplified, gas hydrate-based processes for post-combustion carbon dioxide capture from power station flue gases. The first process, an unpromoted...... hydrate process, operates isothermally at a temperature of 280. K. Applying three consecutive hydrate formation/dissociation stages (three-stage capture process), a carbon dioxide-rich product (97. mol%) is finally delivered at a temperature of 280. K and a pressure of 3.65. MPa. The minimum pressure...... requirement of the first stage is estimated to be 24.9. MPa, corresponding to the incipient hydrate dissociation pressure at 280. K for the considered flue gas. A second simulated carbon dioxide capture process uses tetrahydrofuran as a thermodynamic promoter to reduce the pressure requirements. By doing so...

  20. Police Training in El Salvador: Challenges and Opportunities in Promoting the Community Police Model

    Directory of Open Access Journals (Sweden)

    Luisa Carolina Arévalo Herrera

    2014-05-01

    Full Text Available The Peace Accords emphasized creating a new police force that would be diametrically opposite to previous security forces. This change would have to be expressed symbolically, and from the onset it would have to underscore the fact that the main weapon of the police would be intelligence. From its foundation to June 2011, a total of 30,344 people have graduated from the Academy. Currently, in the process of training new police with greater quality, and modernizing the entire police force, it faces the difficult challenge of adopting the Community Police philosophy to empower this model for action, promoting a new relationship between community and law enforcement, and between managers and operational personnel in the agency. Nevertheless,police training is not enough if there are no significantchanges in the organizational climate and culture within the law enforcement agency.DOI: http://dx.doi.org/10.5377/rpsp.v1i1.1390

  1. Sleep-promoting effects of the GABA/5-HTP mixture in vertebrate models.

    Science.gov (United States)

    Hong, Ki-Bae; Park, Yooheon; Suh, Hyung Joo

    2016-09-01

    The aim of this study was to investigate the sleep-promoting effect of combined γ-aminobutyric acid (GABA) and 5-hydroxytryptophan (5-HTP) on sleep quality and quantity in vertebrate models. Pentobarbital-induced sleep test and electroencephalogram (EEG) analysis were applied to investigate sleep latency, duration, total sleeping time and sleep quality of two amino acids and GABA/5-HTP mixture. In addition, real-time PCR and HPLC analysis were applied to analyze the signaling pathway. The GABA/5-HTP mixture significantly regulated the sleep latency, duration (pHTP mixture modulates both GABAergic and serotonergic signaling. Moreover, the sleep architecture can be controlled by the regulation of GABAA receptor and GABA content with 5-HTP.

  2. Protease-sensitive atelocollagen hydrogels promote healing in a diabetic wound model

    CERN Document Server

    Tronci, Giuseppe; Holmes, Roisin A; Liang, He; Russell, Stephen J; Wood, David J

    2016-01-01

    The design of exudate-managing wound dressings is an established route to accelerated healing, although such design remains a challenge from material and manufacturing standpoints. Aiming towards the clinical translation of knowledge gained in vitro with highly swollen rat tail collagen hydrogels, this study investigated the healing capability in a diabetic mouse wound model of telopeptide-free, protease-inhibiting collagen networks. 4 vinylbenzylation and UV irradiation of type I atelocollagen (AC) led to hydrogel networks with chemical and macroscopic properties comparable to previous collagen analogues, attributable to similar lysine content and dichroic properties. After 4 days in vitro, hydrogels induced nearly 50 RFU% reduction in matrix metalloproteinase (MMP)-9 activity, whilst showing less than 20 wt.-% weight loss. After 20 days in vivo, dry networks promoted 99% closure of 10x10 mm full thickness wounds and accelerated neodermal tissue formation compared to Mepilex. This collagen system can be equi...

  3. Polysaccharides from Ganoderma lucidum Promote Cognitive Function and Neural Progenitor Proliferation in Mouse Model of Alzheimer's Disease

    Directory of Open Access Journals (Sweden)

    Shichao Huang

    2017-01-01

    Full Text Available Promoting neurogenesis is a promising strategy for the treatment of cognition impairment associated with Alzheimer's disease (AD. Ganoderma lucidum is a revered medicinal mushroom for health-promoting benefits in the Orient. Here, we found that oral administration of the polysaccharides and water extract from G. lucidum promoted neural progenitor cell (NPC proliferation to enhance neurogenesis and alleviated cognitive deficits in transgenic AD mice. G. lucidum polysaccharides (GLP also promoted self-renewal of NPC in cell culture. Further mechanistic study revealed that GLP potentiated activation of fibroblast growth factor receptor 1 (FGFR1 and downstream extracellular signal-regulated kinase (ERK and AKT cascades. Consistently, inhibition of FGFR1 effectively blocked the GLP-promoted NPC proliferation and activation of the downstream cascades. Our findings suggest that GLP could serve as a regenerative therapeutic agent for the treatment of cognitive decline associated with neurodegenerative diseases.•G. lucidum polysaccharides (GLP improve cognition in transgenic AD mice•GLP promote neural progenitor proliferation and self-renewal to enhance neurogenesis•GLP potentiate FGFR signalingG. lucidum is a revered medicinal herb for promoting health. Pei and colleagues found that the polysaccharides from G. lucidum (GLP promoted neural progenitor proliferation to enhance neurogenesis and ameliorated cognition deficits in transgenic Alzheimer's disease model mice. These findings suggest that GLP could serve as a regenerative therapeutic agent for the treatment of cognitive decline associated with neurodegenerative diseases.

  4. Simulation and modeling CO2 absorption in biogas with DEA promoted K2CO3 solution in packed column

    Science.gov (United States)

    Nurkhamidah, Siti; Altway, Ali; Airlangga, Bramantyo; Emilia, Dwi Putri

    2017-05-01

    Absorption of carbon dioxide (CO2) using potassium carbonate (K2CO3) is one of biogas purification method. However, K2CO3 have slow mass transfer in liquid phase. So it is necessary to eliminate the disadvantage of CO2 absorption using K2CO3 by adding promotor (activator). Diethanol amine (DEA) is one of promotor which can increase its reaction rate. Simulation and modeling research of the CO2 absorption from biogas with DEA promoted K2CO3 solution has not been conducted. Thus, the main goal of this research is create model and simulation for the CO2 absorption from biogas with DEA promoted K2CO3 solution, then observe the influence of promoter concentration. DEA concentration varies between 1-5 %wt. From the simulation, we concluded that the CO2 removal rise with the increasing of promoter concentration. The highest CO2 removal is 54.5318 % at 5 % wt DEA concentration.

  5. Measuring and modelling of the combined thermodynamic promoting effect of tetrahydrofuran and cyclopentane on carbon dioxide hydrates

    DEFF Research Database (Denmark)

    Herslund, Peter Jørgensen; Daraboina, Nagu; Thomsen, Kaj

    2014-01-01

    promoters due to its significant pressure reducing effect in hydrate forming systems such as those related to carbon dioxide capture.The present work shows that hydrate dissociation pressures may be lowered by up to 22% compared to those of the cyclopentane promoted carbon dioxide hydrate system by addition......This work documents both experimental data, and by thermodynamic modelling, the synergistic effect occurring in promoted carbon dioxide hydrate systems at the simultaneous presence of tetrahydrofuran and cyclopentane.Cyclopentane has previously been considered a reference among gas hydrate...

  6. Policy, competence and participation: empirical evidence for a multilevel health promotion model.

    NARCIS (Netherlands)

    Rütten, A.; Lengerke, T. von; Abel, T.; Kannas, L.; Lüschen, G.; Rodríguez Diaz, J.A.; Vinck, J.; Zee, J. van der

    2000-01-01

    This paper uses data from a European health promotion evaluation study (MAREPS) to empirically test some fundamental assumptions of health promotion theory. Analysis shows that both the competence of individual actors and the opportunities provided for by health-promoting policies are significant pr

  7. Articulation Error Migration: A Comparison of Single Word and Connected Speech Samples.

    Science.gov (United States)

    Healy, Timothy J.; Madison, Charles L.

    1987-01-01

    The study compared frequency and type of articulation error, including error migration, between single word production and connected speech samples when vocabulary was held constant with 20 articulation disordered children (ages 5-12 years). There were significantly more errors in connected speech samples than in single word utterances. (Author/DB)

  8. High Re-Operation Rates Using Conserve Metal-On-Metal Total Hip Articulations

    DEFF Research Database (Denmark)

    Mogensen, S L; Jakobsen, Thomas; Christoffersen, Hardy;

    2016-01-01

    INTRODUCTION: Metal-on-metal hip articulations have been intensely debated after reports of adverse reactions and high failure rates. The aim of this study was to retrospectively evaluate the implant of a metal-on.metal total hip articulation (MOM THA) from a single manufacture in a two...

  9. The Articulation of Korean Coronal Obstruents: Data from Heritage Speakers and Second Language Learners

    Science.gov (United States)

    Ko, Insung

    2013-01-01

    This study investigated where the consonantal constrictions take place when Korean coronal obstruents are articulated since there is disagreement over the place of articulation of these consonants. Unlike other studies in Korean phonetics, which focus on various acoustic features, the current study used static palatography (SPG) in the form of…

  10. Demanding Dynamics - Demand articulation of intermediary organisations in emerging pharmaceutical innovations

    NARCIS (Netherlands)

    Boon, W.P.C.

    2008-01-01

    User involvement in emerging technological fields is carried by so-called demand articulation processes. These demand articulation processes are interactive learning processes in which stakeholders try to address what they perceive as important characteristics of, and to unravel preferences for an e

  11. Articulation Rate and Its Relationship to Disfluency Type, Duration, and Temperament in Preschool Children Who Stutter

    Science.gov (United States)

    Tumanova, Victoria; Zebrowski, Patricia M.; Throneburg, Rebecca N.; Kayikci, Mavis E. Kulak

    2011-01-01

    The purpose of this study was to examine the relationship between articulation rate, frequency and duration of disfluencies of different types, and temperament in preschool children who stutter (CWS). In spontaneous speech samples from 19 CWS (mean age = 3:9; years:months), we measured articulation rate, the frequency and duration of (a) sound…

  12. Children with Developmental Verbal Dyspraxia: Changes in Articulation and Perceived Resilience with Intensive Multimodal Intervention

    Science.gov (United States)

    Martin, Maureen K; Wright, Lindsay Elizabeth; Perry, Susan; Cornett, Daphne; Schraeder, Missy; Johnson, James T.

    2016-01-01

    Research into intervention strategies for developmental verbal dyspraxia (DVD) clearly demonstrates the need to identify effective interventions. The goals of this study were to examine changes in articulation skills following the use of phonetic, multimodal intervention and to consider the relationship between these improved articulation skills…

  13. Sectoral demand articulation : The case of emerging sensor technologies in the drinking water sector

    NARCIS (Netherlands)

    te Kulve, Haico; Konrad, Kornelia Elke

    Demand articulation plays a central role in innovation processes as it reduces uncertainties for innovating firms and offers guidance in innovation processes. Studies into demand articulation processes have mostly focused on users and user-producer interactions and paid less attention to the role of

  14. Articulation Error Migration: A Comparison of Single Word and Connected Speech Samples.

    Science.gov (United States)

    Healy, Timothy J.; Madison, Charles L.

    1987-01-01

    The study compared frequency and type of articulation error, including error migration, between single word production and connected speech samples when vocabulary was held constant with 20 articulation disordered children (ages 5-12 years). There were significantly more errors in connected speech samples than in single word utterances. (Author/DB)

  15. A STUDY ON LIMITATION OF GOVERNMENT INITIATIVE MODEL FOR ALTERNATIVE FUEL VEHICLE (AFV PROMOTION IN CHINA

    Directory of Open Access Journals (Sweden)

    Byunghun Choi

    2016-04-01

    Full Text Available Chinese responsibility for reducing Greenhouse Gas or carbon dioxide emission increases continuously. Chinese government suggested two targets; Alternative Fuel Vehicle output volume 500 thousand and AFV market share 5% by the end of 2011. However any of two targets did not come true. Therefore this study accessed the question, ‘why Chinese government initiative model for AFV promotion has been so poor?’ This study reviewed the transition process for AFV policies in China and made a structural analysis for three key policies since 2009. As a result the number of articles for related industries or factor endowments was relatively more than firm strategy or demand conditions. Also this study accessed the AFV strategy of Six SOEs from the perspective of social responsibility. Six SOEs have more concentrated on electric vehicle rather than hybrid vehicle with following the government leadership. However major EV or HEV models of them mostly were made by Joint Ventures being under control of foreign makers and the JVs have actually controlled over AFV business. So the limitation of Chinese government initiative model resulted from supplier-centric approach with targeting for public transportation and institution consumer, and it caused a failure to create the demand conditions of general customers.

  16. Promoting Social Inclusion through Sport for Refugee-Background Youth in Australia: Analysing Different Participation Models

    Directory of Open Access Journals (Sweden)

    Karen Block

    2017-06-01

    Full Text Available Sports participation can confer a range of physical and psychosocial benefits and, for refugee and migrant youth, may even act as a critical mediator for achieving positive settlement and engaging meaningfully in Australian society. This group has low participation rates however, with identified barriers including costs; discrimination and a lack of cultural sensitivity in sporting environments; lack of knowledge of mainstream sports services on the part of refugee-background settlers; inadequate access to transport; culturally determined gender norms; and family attitudes. Organisations in various sectors have devised programs and strategies for addressing these participation barriers. In many cases however, these responses appear to be ad hoc and under-theorised. This article reports findings from a qualitative exploratory study conducted in a range of settings to examine the benefits, challenges and shortcomings associated with different participation models. Interview participants were drawn from non-government organisations, local governments, schools, and sports clubs. Three distinct models of participation were identified, including short term programs for refugee-background children; ongoing programs for refugee-background children and youth; and integration into mainstream clubs. These models are discussed in terms of their relative challenges and benefits and their capacity to promote sustainable engagement and social inclusion for this population group.

  17. Adipose tissue extract promotes adipose tissue regeneration in an adipose tissue engineering chamber model.

    Science.gov (United States)

    Lu, Zijing; Yuan, Yi; Gao, Jianhua; Lu, Feng

    2016-05-01

    An adipose tissue engineering chamber model of spontaneous adipose tissue generation from an existing fat flap has been described. However, the chamber does not completely fill with adipose tissue in this model. Here, the effect of adipose tissue extract (ATE) on adipose tissue regeneration was investigated. In vitro, the adipogenic and angiogenic capacities of ATE were evaluated using Oil Red O and tube formation assays on adipose-derived stem cells (ASCs) and rat aortic endothelial cells (RAECs), respectively. In vivo, saline or ATE was injected into the adipose tissue engineering chamber 1 week after its implantation. At different time points post-injection, the contents were morphometrically, histologically, and immunohistochemically evaluated, and the expression of growth factors and adipogenic genes was analyzed by enzyme-linked immunosorbent assay (ELISA) and quantitative real-time PCR. With the exception of the baseline control group, in which fat flaps were not inserted into a chamber, the total volume of fat flap tissue increased significantly in all groups, especially in the ATE group. Better morphology and structure, a thinner capsule, and more vessels were observed in the ATE group than in the control group. Expression of angiogenic growth factors and adipogenic markers were significantly higher in the ATE group. ATE therefore significantly promoted adipose tissue regeneration and reduced capsule formation in an adipose tissue engineering chamber model. These data suggest that ATE provides a more angiogenic and adipogenic microenvironment for adipose tissue formation by releasing various cytokines and growth factors that also inhibit capsule formation.

  18. Promoting Sustainable Forest Management Among Stakeholders in the Prince Albert Model Forest, Canada

    Directory of Open Access Journals (Sweden)

    Glen T Hvenegaard

    2015-01-01

    Full Text Available Model Forests are partnerships for shared decision-making to support social, environmental, and economic sustainability in forest management. Relationships among sustainable forest management partners are often strained, but the Prince Albert Model Forest (PAMF represents a process of effective stakeholder involvement, cooperative relationships, visionary planning, and regional landscape management. This article seeks to critically examine the history, drivers, accomplishments, and challenges associated with the PAMF. Four key phases are discussed, representing different funding levels, planning processes, research projects, and partners. Key drivers in the PAMF were funding, urgent issues, provincial responsibility, core of committed people, evolving governance, desire for a neutral organisation, role of protected areas, and potential for mutual benefits. The stakeholders involved in the Model Forest, including the forest industry and associated groups, protected areas, Aboriginal groups, local communities, governments, and research groups, were committed to the project, cooperated on many joint activities, provided significant staffing and financial resources, and gained many benefits to their own organisations. Challenges included declining funding, changing administrative structures, multiple partners, and rotating representatives. The PAMF process promoted consultative and integrated land resource management in the region, and demonstrated the positive results of cooperation between stakeholders interested in sustainable forest management.

  19. Coaching Early Educators to Implement Effective Practices: Using the Pyramid Model to Promote Social-Emotional Development

    Science.gov (United States)

    Fox, Lise; Hemmeter, Mary Louise

    2011-01-01

    The Pyramid Model is a conceptual framework for organizing practices for promoting young children's social-emotional development and preventing and addressing challenging behavior. The authors describe a coaching approach that is focused on supporting early educators' implementation of the Pyramid Model. The authors provide a description of the…

  20. Evaluating the Implementation of the "Pyramid Model for Promoting Social-Emotional Competence" in Early Childhood Classrooms

    Science.gov (United States)

    Hemmeter, Mary Louise; Snyder, Patricia A.; Fox, Lise; Algina, James

    2016-01-01

    We conducted a potential efficacy trial examining the effects of classroom-wide implementation of the "Pyramid Model for Promoting Young Children's Social-Emotional Competence" on teachers' implementation of "Pyramid Model" practices and children's social-emotional skills and challenging behavior. Participants were 40 preschool…

  1. Cyclosporin promotes neurorestoration and cell replacement therapy in pre-clinical models of Parkinson's disease.

    Science.gov (United States)

    Tamburrino, Anna; Churchill, Madeline J; Wan, Oi W; Colino-Sanguino, Yolanda; Ippolito, Rossana; Bergstrand, Sofie; Wolf, Daniel A; Herz, Niculin J; Sconce, Michelle D; Björklund, Anders; Meshul, Charles K; Decressac, Mickael

    2015-12-14

    The early clinical trials using fetal ventral mesencephalic (VM) allografts in Parkinson's disease (PD) patients have shown efficacy (albeit not in all cases) and have paved the way for further development of cell replacement therapy strategies in PD. The preclinical work that led to these clinical trials used allografts of fetal VM tissue placed into 6-OHDA lesioned rats, while the patients received similar allografts under cover of immunosuppression in an α-synuclein disease state. Thus developing models that more faithfully replicate the clinical scenario would be a useful tool for the translation of such cell-based therapies to the clinic. Here, we show that while providing functional recovery, transplantation of fetal dopamine neurons into the AAV-α-synuclein rat model of PD resulted in smaller-sized grafts as compared to similar grafts placed into the 6-OHDA-lesioned striatum. Additionally, we found that cyclosporin treatment was able to promote the survival of the transplanted cells in this allografted state and surprisingly also provided therapeutic benefit in sham-operated animals. We demonstrated that delayed cyclosporin treatment afforded neurorestoration in three complementary models of PD including the Thy1-α-synuclein transgenic mouse, a novel AAV-α-synuclein mouse model, and the MPTP mouse model. We then explored the mechanisms for this benefit of cyclosporin and found it was mediated by both cell-autonomous mechanisms and non-cell autonomous mechanisms. This study provides compelling evidence in favor for the use of immunosuppression in all grafted PD patients receiving cell replacement therapy, regardless of the immunological mismatch between donor and host cells, and also suggests that cyclosporine treatment itself may act as a disease-modifying therapy in all PD patients.

  2. Applying an Educational-participatory Program based on the PRECEDE Model for Promoting Self-esteem and Mental Health of Students in Iran

    Directory of Open Access Journals (Sweden)

    Mahdi Moshki

    2012-01-01

    Conclusion: Health promotion planning by using life skills training based on the PRECEDE model can result in participation and empowerment, in order to promote the self-esteem and mental health of the students.

  3. Bcl-2 promotes malignant progression in a PDGF-B-dependent murine model of oligodendroglioma.

    Science.gov (United States)

    Doucette, Tiffany; Yang, Yuhui; Zhang, Wei; Fuller, Gregory N; Suki, Dima; Fults, Daniel W; Rao, Ganesh

    2011-11-01

    A significant subset of gliomas arises after activation of the proproliferative platelet-derived growth factor (PDGF) pathway. The progression of low-grade gliomas to more malignant tumors may be due to oncogenic cellular programs combining with those suppressing apoptosis. Antiapoptotic genes are overexpressed in a variety of cancers, and the antiapoptotic gene, BCL2, is associated with treatment resistance and tumor recurrence in gliomas. However, the impact of antiapoptotic gene expression to tumor formation and progression is unclear. We overexpressed Bcl-2 in a PDGFB-dependent mouse model of oligodendroglioma, a common glioma subtype, to assess its effect in vivo. We hypothesized that the antiapoptotic effect would complement the proproliferative effect of PDGFB to promote tumor formation and progression to anaplastic oligodendroglioma (AO). Here, we show that coexpression of PDGFB and Bcl-2 results in a higher overall tumor formation rate compared to PDGFB alone. Coexpression of PDGFB and Bcl-2 promotes progression to AO with prominent foci of necrosis, a feature of high-grade gliomas. Median tumor latency was shorter in mice injected with PDGFB and Bcl-2 compared to those injected with PDGFB alone. Although independent expression of Bcl-2 was insufficient to induce tumors, suppression of apoptosis (detected by cleaved caspase-3 expression) was more pronounced in AOs induced by PDGFB and Bcl-2 compared to those induced by PDGFB alone. Tumor cell proliferation (detected by phosphohistone H3 activity) was also more robust in high-grade tumors induced by PDGFB and Bcl-2. Our results indicate that suppressed apoptosis enhances oligodendroglioma formation and engenders a more malignant phenotype.

  4. Donepezil, an acetylcholinesterase inhibitor against Alzheimer's dementia, promotes angiogenesis in an ischemic hindlimb model.

    Science.gov (United States)

    Kakinuma, Yoshihiko; Furihata, Mutsuo; Akiyama, Tsuyoshi; Arikawa, Mikihiko; Handa, Takemi; Katare, Rajesh G; Sato, Takayuki

    2010-04-01

    Our recent studies have indicated that acetylcholine (ACh) protects cardiomyocytes from prolonged hypoxia through activation of the PI3K/Akt/HIF-1alpha/VEGF pathway and that cardiomyocyte-derived VEGF promotes angiogenesis in a paracrine fashion. These results suggest that a cholinergic system plays a role in modulating angiogenesis. Therefore, we assessed the hypothesis that the cholinergic modulator donepezil, an acetylcholinesterase inhibitor utilized in Alzheimer's disease, exhibits beneficial effects, especially on the acceleration of angiogenesis. We evaluated the effects of donepezil on angiogenic properties in vitro and in vivo, using an ischemic hindlimb model of alpha7 nicotinic receptor-deleted mice (alpha7 KO) and wild-type mice (WT). Donepezil activated angiogenic signals, i.e., HIF-1alpha and VEGF expression, and accelerated tube formation in human umbilical vein endothelial cells (HUVECs). ACh and nicotine upregulated signal transduction with acceleration of tube formation, suggesting that donepezil promotes a common angiogenesis pathway. Moreover, donepezil-treated WT exhibited rich capillaries with enhanced VEGF and PCNA endothelial expression, recovery from impaired tissue perfusion, prevention of ischemia-induced muscular atrophy with sustained surface skin temperature in the limb, and inhibition of apoptosis independent of the alpha7 receptor. Donepezil exerted comparably more effects in alpha7 KO in terms of angiogenesis, tissue perfusion, biochemical markers, and surface skin temperature. Donepezil concomitantly elevated VEGF expression in intracardiac endothelial cells of WT and alpha7 KO and further increased choline acetyltransferase (ChAT) protein expression, which is critical for ACh synthesis in endothelial cells. The present study concludes that donepezil can act as a therapeutic tool to accelerate angiogenesis in cardiovascular disease patients.

  5. Is Iẕlak a Subject of Articulation?

    Directory of Open Access Journals (Sweden)

    Nazife Nihal İnce

    2015-12-01

    Full Text Available In this assay I have studied the structure of iẕlak which took place in disciplines that interested in Arabic phonetics in some way. The structure of iẕlak, in many field related to phonetics, has been used to express one of the conditions made by the organs during the process of producing speak sounds. But this structure didn’t mentioned in the earliest sources and in some of the latests. On the other hand we have noticed that the explanations of iẕlak term in the earliest works and the latest works of tacwid were different, and also that the new explanation was getting widely accepted. To follow this structure, which it’s all definitions were connected with its root meaning, we reviewed classical dictionaries, works concerned with Arabic language, tacwid works and other sources. The study has pointed out that although iẕlak is an affecting characteristic which influences the sound interactions, it is basically not an articulation subject.

  6. Human-like Manipulation Planning for Articulated Manipulator

    Institute of Scientific and Technical Information of China (English)

    Yahui Gan; Xianzhong Dai

    2012-01-01

    A new method based on human-likeness assessment and optimization concept to solve the problem of human-like manipulation planning for articulated robot is proposed in this paper.This method intrinsically formulates the problem as a constrained optimization problem in robot configuration space.The robot configuration space is divided into different subregions by human likeness assessment.A widely used strategy,Rapid Upper Limb Assessment (RULA) in applied ergonomics,is adopted here to evaluate the human likeness of robot configuration.A task compatibility measurement of the robot velocity transmission ratio along a specified direction is used as the target function for the optimization problem.Simple illustrative examples of this method applied to a two Degree of Freedom (DOF) planar robot that resembles the upper limb of a human are presented.Further applications to a humanoid industrial robot SDA10D are also presented.The reasonable planning results for these applications assert the effectiveness of our method.

  7. Decoding of covert vowel articulation using electroencephalography cortical currents

    Directory of Open Access Journals (Sweden)

    Natsue eYoshimura

    2016-05-01

    Full Text Available With the goal of providing assistive technology for the communication impaired, we proposed electroencephalography (EEG cortical currents as a new approach for EEG-based brain-computer interface spellers. EEG cortical currents were estimated with a variational Bayesian method that uses functional magnetic resonance imaging (fMRI data as a hierarchical prior. EEG and fMRI data were recorded from ten healthy participants during covert articulation of Japanese vowels /a/ and /i/, as well as during a no-imagery control task. Applying a sparse logistic regression (SLR method to classify the three tasks, mean classification accuracy using EEG cortical currents was significantly higher than that using EEG sensor signals and was also comparable to accuracies in previous studies using electrocorticography. SLR weight analysis revealed vertices of EEG cortical currents that were highly contributive to classification for each participant, and the vertices showed discriminative time series signals according to the three tasks. Furthermore, functional connectivity analysis focusing on the highly contributive vertices revealed positive and negative correlations among areas related to speech processing. As the same findings were not observed using EEG sensor signals, our results demonstrate the potential utility of EEG cortical currents not only for engineering purposes such as brain-computer interfaces but also for neuroscientific purposes such as the identification of neural signaling related to language processing.

  8. Vocal-tract filtering by lingual articulation in a parrot.

    Science.gov (United States)

    Beckers, Gabriël J L; Nelson, Brian S; Suthers, Roderick A

    2004-09-07

    Human speech and bird vocalization are complex communicative behaviors with notable similarities in development and underlying mechanisms. However, there is an important difference between humans and birds in the way vocal complexity is generally produced. Human speech originates from independent modulatory actions of a sound source, e.g., the vibrating vocal folds, and an acoustic filter, formed by the resonances of the vocal tract (formants). Modulation in bird vocalization, in contrast, is thought to originate predominantly from the sound source, whereas the role of the resonance filter is only subsidiary in emphasizing the complex time-frequency patterns of the source (e.g., but see ). However, it has been suggested that, analogous to human speech production, tongue movements observed in parrot vocalizations modulate formant characteristics independently from the vocal source. As yet, direct evidence of such a causal relationship is lacking. In five Monk parakeets, Myiopsitta monachus, we replaced the vocal source, the syrinx, with a small speaker that generated a broad-band sound, and we measured the effects of tongue placement on the sound emitted from the beak. The results show that tongue movements cause significant frequency changes in two formants and cause amplitude changes in all four formants present between 0.5 and 10 kHz. We suggest that lingual articulation may thus in part explain the well-known ability of parrots to mimic human speech, and, even more intriguingly, may also underlie a speech-like formant system in natural parrot vocalizations.

  9. Articulated dental cast analysis of asymptomatic and symptomatic populations

    Science.gov (United States)

    Cordray, Frank E

    2016-01-01

    Dental instrumentation has long provided insight into the mechanism of musculo-skeletal function of the gnathic system. While large population studies associate dental arch displacement (DAD), especially laterally, with symptoms, mandibular condyle displacement (CD) resulting from DAD has not been targeted as possibly etiologic in the production of common muscle contraction headache (CMCH) and temporo-mandibular dysfunction (TMD). The objective was to evaluate the three-dimensional nature of DAD and CD between the seated condylar position (SCP) and the intercuspal position (ICP) and to compare results derived from large deprogrammed asymptomatic and symptomatic populations. A total of 1 192 sets of dental casts collected from asymptomatic and symptomatic populations were articulated in the SCP. The initial occlusal contact, DAD, and condylar displacement were evaluated for frequency, direction, and magnitude of displacement between the SCP and ICP. The data revealed significant displacement between the SCP and ICP of the condyles (displaced most frequently inferior (down) and posterior (distal)) and substantially increased frequency and magnitude of displacement of the dental arches (with posterior premature occlusal contacts, increased overjet, decreased overbite, midline differences, and occlusal classification changes) in symptomatic subjects. These discrepancies were statistically significant and clinically significant. The data support the concept of increased DAD and CD with dysfunction. Transverse condylar displacement, commonly presenting with dental cross bite, may be associated with CMCH and TMD. Displacement of the mandibular condyle may be an etiologic factor in CMCH and dysfunction of the temporo-mandibular joint. PMID:27357324

  10. Design and fabrication of an articulated four axes microrobot arm

    Science.gov (United States)

    Zhang, Ruoshi; Yang, Zhong; Wei, Danming; Popa, Dan O.

    2017-05-01

    In order to carry out nanomanufacturing tasks, a microrobot requires both high precision and high reliability over prolonged periods of time. Articulated Four-Axis Microrobots (AFAM) have been introduced a decade ago as millimetric microrobots capable of carrying out nanoscale tasks. The original robot design relied on a Micro Electro Mechanical (MEMS) actuator bank positioned onto a Silicon substrate, and an assembled arm mechanically coupled to the actuators through a cable. Movement of two thermal actuator banks positions the AFAM's end effector in 3-Dimensional space with approximately 75 microns workspace and 50 nm repeatability. However, failure of the AFAM's cable mechanism was observed after less than 1 million cycles. In this paper, we propose a novel arm mechanism for AFAM that improve its performance. The design presented in this article substitutes the "wire-gluing" cable with an anchored electrostatic actuator, and therefore it simplifies assembly requirements, reduces overall footprint of the microrobot, and achieves higher operating frequency. Simulation results are presented for a rotary electrostatic comb drive as basis for the microrobot arm with overall dimensions of 2 mm × 2 mm. The AFAM arm cantilever is 1 mm long to achieve a workspace of dimension of 75 microns along the vertical axis. Experimental evaluation of the design was accomplished using a prototype fabricated on a silicon on insulator (SOI) wafer processed with the deep reactive ion etching (DRIE) process.

  11. Decoding of Covert Vowel Articulation Using Electroencephalography Cortical Currents

    Science.gov (United States)

    Yoshimura, Natsue; Nishimoto, Atsushi; Belkacem, Abdelkader Nasreddine; Shin, Duk; Kambara, Hiroyuki; Hanakawa, Takashi; Koike, Yasuharu

    2016-01-01

    With the goal of providing assistive technology for the communication impaired, we proposed electroencephalography (EEG) cortical currents as a new approach for EEG-based brain-computer interface spellers. EEG cortical currents were estimated with a variational Bayesian method that uses functional magnetic resonance imaging (fMRI) data as a hierarchical prior. EEG and fMRI data were recorded from ten healthy participants during covert articulation of Japanese vowels /a/ and /i/, as well as during a no-imagery control task. Applying a sparse logistic regression (SLR) method to classify the three tasks, mean classification accuracy using EEG cortical currents was significantly higher than that using EEG sensor signals and was also comparable to accuracies in previous studies using electrocorticography. SLR weight analysis revealed vertices of EEG cortical currents that were highly contributive to classification for each participant, and the vertices showed discriminative time series signals according to the three tasks. Furthermore, functional connectivity analysis focusing on the highly contributive vertices revealed positive and negative correlations among areas related to speech processing. As the same findings were not observed using EEG sensor signals, our results demonstrate the potential utility of EEG cortical currents not only for engineering purposes such as brain-computer interfaces but also for neuroscientific purposes such as the identification of neural signaling related to language processing. PMID:27199638

  12. Assessing the Physical Activity of Health Volunteers Based on the Pender’s Health Promotion Model

    Directory of Open Access Journals (Sweden)

    Rahimian M.* MSc,

    2015-12-01

    Full Text Available Aims Physical inactivity has been identified as the 4th leading risk factor for global mortality causing an estimated of 3.2million deaths per year. This study aimed to assess the physical activity of health volunteers with Pender’s Health Promotion Model. Instrument & Methods This cross-sectional analytical study was performed on 80 health volunteers in Torbat-e-Jam City, Iran, in 2015. A researcher-made questionnaire with the following sections was used to gather data; perceived benefits, perceived barriers, selfefficacy, interpersonal influences, positive emotion, commitment, modeling and competing preferences. SPSS 16 sofware was used to analyze data by independent T, Pearson’s correlation coefficient and linear regression tests. Findings There was no significant difference between the scores according to educational levels, age groups, BMI score, marital status, habitat and experience as a health volunteer duration. Physical activity had positive correlation with perceived benefits, self-efficacy, commitment, positive emotion and situational influences and a negative correlation with perceived barriers. Situational influences, as the strongest predictor of the physical activity, predicted 35.1% of it and then positive emotions predicted 34.7% and self-efficacy predicted 23.4% of physical activity. Conclusion The level of physical activity in health volunteers of Torbat-e-Jam City, Iran, is not appropriate and is less than moderate.

  13. In vivo measurement of epidermal thickness changes associated with tumor promotion in murine models

    Science.gov (United States)

    Phillips, Kevin G.; Samatham, Ravikant; Choudhury, Niloy; Gladish, James C.; Thuillier, Philippe; Jacques, Steven L.

    2010-07-01

    The characterization of tissue morphology in murine models of pathogenesis has traditionally been carried out by excision of affected tissues with subsequent immunohistological examination. Excision-based histology provides a limited two-dimensional presentation of tissue morphology at the cost of halting disease progression at a single time point and sacrifice of the animal. We investigate the use of noninvasive reflectance mode confocal scanning laser microscopy (rCSLM) as an alternative tool to biopsy in documenting epidermal hyperplasia in murine models exposed to the tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA). An automated technique utilizing average axial rCSLM reflectance profiles is used to extract epidermal thickness values from rCSLM data cubes. In comparisons to epidermal thicknesses determined from hematoxylin and eosin (H&E) stained tissue sections, we find no significant correlation to rCSLM-derived thickness values. This results from method-specific artifacts: physical alterations of tissue during H&E preparation in standard histology and specimen-induced abberations in rCSLM imaging. Despite their disagreement, both histology and rCSLM methods reliably measure statistically significant thickness changes in response to TPA exposure. Our results demonstrate that in vivo rCSLM imaging provides epithelial biologists an accurate noninvasive means to monitor cutaneous pathogenesis.

  14. The DREAM model's effectiveness in health promotion of AIDS patients in Africa.

    Science.gov (United States)

    Magnano San Lio, M; Mancinelli, S; Palombi, L; Buonomo, E; Altan, A Doro; Germano, P; Magid, N A; Pesaresi, A; Renzi, E; Scarcella, P; Zimba, I; Marazzi, M C

    2009-03-01

    This study evaluates the effectiveness of a holistic model for treating people living with AIDS in Africa; the model aims to improve knowledge about AIDS prevention and care, increase trust in the health centre, impact behaviour, and promote a high level of adherence to HAART. The study took place in the context of the DREAM (Drug Resource Enhancement against AIDS and Malnutrition) programme in Mozambique, designed by the Community of Sant'Egidio to treat HIV patients in Africa. It provides patients with free anti-retroviral drugs, laboratory tests (including viral load), home care and nutritional support. This is a prospective study involving 531 patients over a 12-month period. The patients, predominantly poor and with a low level of education, demonstrated a good level of knowledge about AIDS (more than 90% know how it is transmitted) and trust in the treatment, with a relatively small percentage turning to traditional healers. Overall the patients had a low level of engaging in risky sexual behaviour and a very good level of adherence to HAART (69.5% of the 531 subjects had a pill count higher than 95%). The positive results of the programme's educational initiatives were confirmed with the patients' good clinical results.

  15. Community-based senior health promotion program using a collaborative practice model: the Escalante Health Partnerships.

    Science.gov (United States)

    Nuñez, Diane E; Armbruster, Charlotte; Phillips, Wayne T; Gale, Betty J

    2003-01-01

    Recent research demonstrates that, although the risk of disease and disability clearly increases with age, poor health need not be an inevitable consequence of aging. A healthy lifestyle is more influential than genetic factors in assisting older adults avoid the decline and deterioration traditionally associated with aging. Many effective strategies for reducing disease and disability are widely underused. The Escalante Health Partnerships is a community-based, nurse-managed health promotion and chronic disease care management program for community-residing older adults. The program base supports a multidisciplinary, collaborative practice model, which has responded to the health needs of members of a community at high risk of having or developing chronic conditions. Preliminary comparisons of the health status of program participants with national norms demonstrate that these seniors report better general health, performance of roles, and social functioning, with the strongest correlations occurring between general health and vitality and between general health and role-physical. In addition, these participants have 4.2 doctor visits per year, in comparison with 7.1 office visits for a national comparison group and 1.6 hospital days per year, in comparison with 2.1 hospital days in the same referenced population. This collaborative partnership is a model that can be replicated cost-effectively in other communities.

  16. Calibration of a flexible measurement system based on industrial articulated robot and structured light sensor

    Science.gov (United States)

    Mu, Nan; Wang, Kun; Xie, Zexiao; Ren, Ping

    2017-05-01

    To realize online rapid measurement for complex workpieces, a flexible measurement system based on an articulated industrial robot with a structured light sensor mounted on the end-effector is developed. A method for calibrating the system parameters is proposed in which the hand-eye transformation parameters and the robot kinematic parameters are synthesized in the calibration process. An initial hand-eye calibration is first performed using a standard sphere as the calibration target. By applying the modified complete and parametrically continuous method, we establish a synthesized kinematic model that combines the initial hand-eye transformation and distal link parameters as a whole with the sensor coordinate system as the tool frame. According to the synthesized kinematic model, an error model is constructed based on spheres' center-to-center distance errors. Consequently, the error model parameters can be identified in a calibration experiment using a three-standard-sphere target. Furthermore, the redundancy of error model parameters is eliminated to ensure the accuracy and robustness of the parameter identification. Calibration and measurement experiments are carried out based on an ER3A-C60 robot. The experimental results show that the proposed calibration method enjoys high measurement accuracy, and this efficient and flexible system is suitable for online measurement in industrial scenes.

  17. Aggressiveness of human melanoma xenograft models is promoted by aneuploidy-driven gene expression deregulation.

    Science.gov (United States)

    Mathieu, Véronique; Pirker, Christine; Schmidt, Wolfgang M; Spiegl-Kreinecker, Sabine; Lötsch, Daniela; Heffeter, Petra; Hegedus, Balazs; Grusch, Michael; Kiss, Robert; Berger, Walter

    2012-04-01

    Melanoma is a devastating skin cancer characterized by distinct biological subtypes. Besides frequent mutations in growth- and survival-promoting genes like BRAF and NRAS, melanomas additionally harbor complex non-random genomic alterations. Using an integrative approach, we have analysed genomic and gene expression changes in human melanoma cell lines (N=32) derived from primary tumors and various metastatic sites and investigated the relation to local growth aggressiveness as xenografts in immuno-compromised mice (N=22). Although the vast majority >90% of melanoma models harbored mutations in either BRAF or NRAS, significant differences in subcutaneous growth aggressiveness became obvious. Unsupervised clustering revealed that genomic alterations rather than gene expression data reflected this aggressive phenotype, while no association with histology, stage or metastatic site of the original melanoma was found. Genomic clustering allowed separation of melanoma models into two subgroups with differing local growth aggressiveness in vivo. Regarding genes expressed at significantly altered levels between these subgroups, a surprising correlation with the respective gene doses (>85% accordance) was found. Genes deregulated at the DNA and mRNA level included well-known cancer genes partly already linked to melanoma (RAS genes, PTEN, AURKA, MAPK inhibitors Sprouty/Spred), but also novel candidates like SIPA1 (a Rap1GAP). Pathway mining further supported deregulation of Rap1 signaling in the aggressive subgroup e.g. by additional repression of two Rap1GEFs. Accordingly, siRNA-mediated down-regulation of SIPA1 exerted significant effects on clonogenicity, adherence and migration in aggressive melanoma models. Together our data suggest that an aneuploidy-driven gene expression deregulation drives local aggressiveness in human melanoma.

  18. Influence of Articulating Paper Thickness on Occlusal Contacts Registration: A Preliminary Report.

    Science.gov (United States)

    Brizuela-Velasco, Aritza; Álvarez-Arenal, Ángel; Ellakuria-Echevarria, Joseba; del Río-Highsmith, Jaime; Santamaría-Arrieta, Gorka; Martín-Blanco, Nerea

    2015-01-01

    The objective of this preliminary study was to determine if the occlusal contact surface registered with an articulating paper during fixed prosthodontic treatment was contained within the area marked on a thicker articulating paper. This information would optimize any necessary occlusal adjustment of a prosthesis' veneering material. A convenience sample of 15 patients who were being treated with an implant-supported fixed singleunit dental prosthesis was selected. Occlusal registrations were obtained from each patient using 12-μm, 40-μm, 80-μm, and 200-μm articulating paper. Photographs of the occlusal registrations were obtained, and pixel measurements of the surfaces were taken and overlapped for comparison. The results showed that the thicker the articulating paper, the larger the occlusal contact area obtained. The differences were statistically significant. In all cases, the occlusal registrations obtained with the thinnest articulating paper were contained within the area marked on the thickest articulating paper. The results suggested that the use of thin articulating papers (12-μm or 40-μm) can avoid unnecessary grinding of veneering material or teeth during occlusal adjustment.

  19. Cross-language differences of articulation rate and its transfer into Japanese as a second language.

    Science.gov (United States)

    Amino, Kanae; Osanai, Takashi

    2015-04-01

    Recently, the articulation rate has been attracting attention in forensic speech investigation as an acoustic feature that varies across speakers, dialects, and languages. The present study investigates how cross-language differences in the articulation rate are transferred into Japanese as a second language. Participants were speakers of Japanese, Chinese, Korean, and Thai. They were recorded while they read a passage in their native language and in Japanese. Local and global articulation rates were calculated based on the number of syllables as well as the number of morae for Japanese speech. When we compared the articulation rate of the native languages, Japanese was the fastest, then Korean, Chinese, and Thai in that order. Also, a significant positive correlation was observed between the articulation rate of the native language and that of the second language. A gender difference was found in the articulation rate of some languages, with males speaking faster than females. The effect of age was limited to Thai speakers only. Accent discrimination and identification experiments were conducted and the results revealed that native and non-native accents could be correctly discriminated just by the articulation rate.

  20. Imprecise vowel articulation as a potential early marker of Parkinson's disease: effect of speaking task.

    Science.gov (United States)

    Rusz, Jan; Cmejla, Roman; Tykalova, Tereza; Ruzickova, Hana; Klempir, Jiri; Majerova, Veronika; Picmausova, Jana; Roth, Jan; Ruzicka, Evzen

    2013-09-01

    The purpose of this study was to analyze vowel articulation across various speaking tasks in a group of 20 early Parkinson's disease (PD) individuals prior to pharmacotherapy. Vowels were extracted from sustained phonation, sentence repetition, reading passage, and monologue. Acoustic analysis was based upon measures of the first (F1) and second (F2) formant of the vowels /a/, /i/, and /u/, vowel space area (VSA), F2i/F2u and vowel articulation index (VAI). Parkinsonian speakers manifested abnormalities in vowel articulation across F2u, VSA, F2i/F2u, and VAI in all speaking tasks except sustained phonation, compared to 15 age-matched healthy control participants. Findings suggest that sustained phonation is an inappropriate task to investigate vowel articulation in early PD. In contrast, monologue was the most sensitive in differentiating between controls and PD patients, with classification accuracy up to 80%. Measurements of vowel articulation were able to capture even minor abnormalities in speech of PD patients with no perceptible dysarthria. In conclusion, impaired vowel articulation may be considered as a possible early marker of PD. A certain type of speaking task can exert significant influence on vowel articulation. Specifically, complex tasks such as monologue are more likely to elicit articulatory deficits in parkinsonian speech, compared to other speaking tasks.

  1. Informal work and formal plans: articulating the active role of patients in cancer trajectories

    Directory of Open Access Journals (Sweden)

    Rikke Juul Dalsted

    2012-12-01

    Full Text Available Introduction: Formal pathways models outline that patients should receive information in order to experience a coherent journey but do not describe an active role for patients or their relatives. The aim of this is paper is to articulate and discuss the active role of patients during their cancer trajectories.  Methods and theory: An in-depth case study of patient trajectories at a Danish hospital and surrounding municipality using individual interviews with patients. Theory about trajectory and work by Strauss was included.  Results: Patients continuously took initiatives to organize their treatment and care. They initiated processes in the trajectories, and acquired information, which they used to form their trajectories.  Patients presented problems to the healthcare professionals in order to get proper help when needed.  Discussion: Work done by patients was invisible and not perceived as work. The patients' requests were not sufficiently supported in the professional organisation of work or formal planning. Patients' insertion and use of information in their trajectories challenged professional views and working processes. And the design of the formal pathway models limits the patients´ active participation. When looking at integrated care from the perspective of patients, the development of a more holistic and personalized approach is needed. Introduction: Formal pathway models outline that patients should receive information in order to experience a coherent journey but do not describe an active role for patients or their relatives. The aim of this is paper is to articulate and discuss the active role of patients during their cancer trajectories. Methods and theory: An in-depth case study of patient trajectories at a Danish hospital and surrounding municipality using individual interviews with patients. Theory about trajectory and work by Strauss was included. Results: Patients continuously took initiatives to organize their

  2. An Analysis of Triple Articulation of Cinematic Code in Eco's Image Criticism%浅析艾柯形象批评中电影代码的三层分节

    Institute of Scientific and Technical Information of China (English)

    孙恒存

    2012-01-01

      Articulation theory has developed from linguistics to semiotics, from general articulation to limited articulation, and from double-articulation to triple articulation. Eco's triple articulation is derived mainly from Metz's, Puri Eto's, and Pasolini's cinematic and semiotic theories. In his image criticism, Eco has established a model of triple articulation: rhetoric, sign, and seme, and then he ana-lyzed photographic photos and moving images and then established a triple articulation of cinematic code, all of which emphasize the semantic richness of cinematic communication and refresh the understanding of the image.%  分节理论经历了从语言学扩展到符号学,从普遍分节到有限分节,从双重分节到三层分节的发展过程。艾柯的三层分节主要源自麦茨、普里埃托和帕索里尼的电影和符号学理论。艾柯在对形象的批评中建立了一套肖似代码的三层分节模式:修辞元、记号、意素。艾柯先后在摄影照片和活动影像上进行模式化分析,从而建立了电影代码的三层分节方式。艾柯的三层分节及其在电影代码中的分析,强调了电影通信形式的语义丰富性,翻新了对影像的理解

  3. Very fast motion planning for highly dexterous-articulated robots

    Science.gov (United States)

    Challou, Daniel J.; Gini, Maria; Kumar, Vipin

    1994-01-01

    Due to the inherent danger of space exploration, the need for greater use of teleoperated and autonomous robotic systems in space-based applications has long been apparent. Autonomous and semi-autonomous robotic devices have been proposed for carrying out routine functions associated with scientific experiments aboard the shuttle and space station. Finally, research into the use of such devices for planetary exploration continues. To accomplish their assigned tasks, all such autonomous and semi-autonomous devices will require the ability to move themselves through space without hitting themselves or the objects which surround them. In space it is important to execute the necessary motions correctly when they are first attempted because repositioning is expensive in terms of both time and resources (e.g., fuel). Finally, such devices will have to function in a variety of different environments. Given these constraints, a means for fast motion planning to insure the correct movement of robotic devices would be ideal. Unfortunately, motion planning algorithms are rarely used in practice because of their computational complexity. Fast methods have been developed for detecting imminent collisions, but the more general problem of motion planning remains computationally intractable. However, in this paper we show how the use of multicomputers and appropriate parallel algorithms can substantially reduce the time required to synthesize paths for dexterous articulated robots with a large number of joints. We have developed a parallel formulation of the Randomized Path Planner proposed by Barraquand and Latombe. We have shown that our parallel formulation is capable of formulating plans in a few seconds or less on various parallel architectures including: the nCUBE2 multicomputer with up to 1024 processors (nCUBE2 is a registered trademark of the nCUBE corporation), and a network of workstations.

  4. Sometimes it does hurt to ask: the constructive role of articulating impressions.

    Science.gov (United States)

    White, Lee C; Pothos, Emmanuel M; Busemeyer, Jerome R

    2014-10-01

    Decisions can sometimes have a constructive role, so that the act of, for example, choosing one option over another creates a preference for that option (e.g., Ariely & Norton, 2008; Payne, Bettman, & Johnson, 1993; Sharot, Velasquez, & Dolan, 2010; Sherman, 1980). In this work we explore the constructive role of just articulating an impression, for a presented visual stimulus, as opposed to making a choice (specifically, the judgments we employ are affective evaluations). Using quantum probability theory, we outline a cognitive model formalizing such a constructive process. We predict a simple interaction, in relation to how a second image is evaluated, following the presentation of a first image, depending on whether there is a rating for the first image or not. The interaction predicted by the quantum model was confirmed across three experiments and a variety of control manipulations. The advantages of using quantum probability theory to model the present results, compared with existing models of sequence order effects in judgment (e.g., Hogarth & Einhorn, 1992) or other theories of constructive processes when a choice is made (e.g., Festinger, 1957; Sharot et al., 2010) are discussed.

  5. Radiation promotes cancer cell metastasis via EMT induction in mouse model

    Energy Technology Data Exchange (ETDEWEB)

    Park, Jongkuk; Kang, Sungwook; Hwang, Sanggu; Um, Hongduck [Department of Radiation Cancer, New York (United States); Jang, Su Jin; Kang, Joohyun [Molecular Imaging Research Center, Charlestown (United States); Park, Sunhoo [Korea Institute of Radiological and Medical Sciences, Seoul (Korea, Republic of); Kim, Wunjae [Chungbuk National Univ., Cheongju (Korea, Republic of)

    2013-05-15

    Whether γ-IR-induced invasion and metastasis are stimulated in our in vitro C6L cell line and in vivo systems, and further identify the associated changes in signal pathways or mice physiology. We constructed an animal model system with a view to clarifying the intracellular molecular events underlying the promotion of metastasis after γ-IR treatment for primary cancer and developing effective anti-metastatic reagents. Our results demonstrate that γ-IR treatment of cancer cell lines and mice xenografts triggers invasion and metastasis. In particular, γ-IR-treated cancer cells or mouse xenografts and metastatic lesions in mice bearing γ-IR-treated xenografts also display typical EMT marker expression patterns, such as increased venetum or MMP-2 expression, decreased E-chondron, and enhanced activity of MMP-2. Our results collectively suggest that γ-IR-induced invasion or metastasis results from induction of EMT, and inhibition of EMT may thus be a means to enhance the effectiveness of radiation therapy. Our results also suggested EMT might be one of the major therapeutic targets to block metastasis.

  6. Community care of individuals at risk of suicide: the Life Promotion Clinic model

    Directory of Open Access Journals (Sweden)

    Kairi Kolves

    2013-09-01

    Full Text Available Assistance to suicidal patients is problematic both at the hospital and community care level. Inadequacy of facilities, pressured personnel, long waiting time, and professional and social stigmatization are just some of the many issues that interfere with successful treatment. The goal of this paper is to present the functioning of the Life Promotion Clinic (LPC, Australia, and describe its users. The LPC is the first specialized outpatient service in Australia dedicated to the treatment of individuals with suicidal thoughts and behaviors. A description of the service and characteristics of its clients (demographic, psychopathology, risk of suicide are herein presented. Data were collected for 63 male and 175 female patients who attended the LPC over a three-year period. Patients were mostly single females, aged up to 44 years, poorly educated, unemployed or on a pension/benefit. The majority of patients reported at least one suicide attempt, severe depression and anxiety scores, moderate-severe feelings of hopelessness, and high impulsiveness scores. Compared to females, male patients presented with more active desire to kill themselves and higher level of suicidal ideation. We can conclude that establishing a specialist service for treatment of individuals at increased risk for suicide requires consideration of both patient and clinicians needs. The LPC presents an innovative model of community service, capable of engaging patients with serious mental health issues, while making the service accessible to people from various social categories.

  7. Imitation of suprasegmental patterns by five-year-old children with adequate and inadequate articulation.

    Science.gov (United States)

    Shadden, B B; Asp, C W; Tonkovich, J D; Mason, D

    1980-08-01

    Ten five-year-old children with adequate articulation skills and 10 five-year-old children with inadequate articulation skills were administered the Templin-Darley Test of Articulation and the Test of Rhythm and Intonation Patterns (TRIP). Differences between the adequate and inadequate groups in terms of the mean percentage correct and the correlations between TRIP and Templin-Darley Test scores within groups were statistically nonsignificant. Item analysis revealed no differences between groups in the pattern of performance on the three subtests of the TRIP or on specific test items. The possible effects of therapy enrollment on suprasegmental test performance are discussed, and future research needs are suggested.

  8. Improving the digital workflow: direct transfer from patient to virtual articulator.

    Science.gov (United States)

    Solaberrieta, Eneko; Minguez, Rikardo; Etxaniz, Olatz; Barrenetxea, Lander

    2013-01-01

    When designing a custom-made dental restoration, using a digital workflow represents an important advance over mechanical tools such as facebows or mechanical articulators. When using virtual scanning procedures, there is a direct transfer from the patient to the articulator. This paper presents a novel methodology to design custom-made restorations. This new approach permits the transfer of all data directly from the patient to the virtual articulator, always taking into account the kinematics of the mandible. Rapid further developments can be expected in the near future.

  9. Health Promotion Efforts as Predictors of Physical Activity in Schools: An Application of the Diffusion of Innovations Model

    Science.gov (United States)

    Glowacki, Elizabeth M.; Centeio, Erin E.; Van Dongen, Daniel J.; Carson, Russell L.; Castelli, Darla M.

    2016-01-01

    Background: Implementing a comprehensive school physical activity program (CSPAP) effectively addresses public health issues by providing opportunities for physical activity (PA). Grounded in the Diffusion of Innovations model, the purpose of this study was to identify how health promotion efforts facilitate opportunities for PA. Methods: Physical…

  10. Promoting Psychological Well-Being in an Urban School Using the Participatory Culture-Specific Intervention Model

    Science.gov (United States)

    Bell, Patrick B.; Summerville, Meredith A.; Nastasi, Bonnie K.; Patterson, Julie; Earnshaw, Elizabeth

    2015-01-01

    School psychology has recently reconceptualized its service provision model to include multitiered systems of academic and psychosocial promotion, prevention, and intervention. The availability of evidence-based programs and advances in school consultation theory accompany the paradigm shift of the field. Despite these advances, implementing…

  11. The Behavioral Ecological Model as a Framework for School-Based Anti-Bullying Health Promotion Interventions

    Science.gov (United States)

    Dresler-Hawke, Emma; Whitehead, Dean

    2009-01-01

    This article presents a conceptual strategy which uses the Behavioral Ecological Model (BEM) as a health promotion framework to guide school-based bullying awareness programs and subsequent anti-bullying strategies for school nursing practice. Anti-bullying frameworks and tools are scarce despite the extent of the problem of bullying. This article…

  12. A Social Partnership Model to Promote Educators' Development in Mauritius through Formal and Informal Capacity-Building Initiatives

    Science.gov (United States)

    Santally, Mohammad Issack; Cooshna-Naik, Dorothy; Conruyt, Noel; Wing, Caroline Koa

    2015-01-01

    This paper describes a social partnership model based on the living lab concept to promote the professional development of educators through formal and informal capacity-building initiatives. The aim is to have a broader impact on society through community outreach educational initiatives. A Living Lab is an environment for user-centered…

  13. Promoting Psychological Well-Being in an Urban School Using the Participatory Culture-Specific Intervention Model

    Science.gov (United States)

    Bell, Patrick B.; Summerville, Meredith A.; Nastasi, Bonnie K.; Patterson, Julie; Earnshaw, Elizabeth

    2015-01-01

    School psychology has recently reconceptualized its service provision model to include multitiered systems of academic and psychosocial promotion, prevention, and intervention. The availability of evidence-based programs and advances in school consultation theory accompany the paradigm shift of the field. Despite these advances, implementing…

  14. Reorienting health services in the Northern Territory of Australia: a conceptual model for building health promotion capacity in the workforce.

    Science.gov (United States)

    Judd, Jenni; Keleher, Helen

    2013-06-01

    Reorienting work practices to include health promotion and prevention is complex and requires specific strategies and interventions. This paper presents original research that used 'real-world' practice to demonstrate that knowledge gathered from practice is relevant for the development of practice-based evidence. The paper shows how practitioners can inform and influence improvements in health promotion practice. Practitioner-informed evidence necessarily incorporates qualitative research to capture the richness of their reflective experiences. Using a participatory action research (PAR) approach, the research question asked 'what are the core dimensions of building health promotion capacity in a primary health care workforce in a real-world setting?' PAR is a method in which the researcher operates in full collaboration with members of the organisation being studied for the purposes of achieving some kind of change, in this case to increase the amount of health promotion and prevention practice within this community health setting. The PAR process involved six reflection and action cycles over two years. Data collection processes included: survey; in-depth interviews; a training intervention; observations of practice; workplace diaries; and two nominal groups. The listen/reflect/act process enabled lessons from practice to inform future capacity-building processes. This research strengthened and supported the development of health promotion to inform 'better health' practices through respectful change processes based on research, practitioner-informed evidence, and capacity-building strategies. A conceptual model for building health promotion capacity in the primary health care workforce was informed by the PAR processes and recognised the importance of the determinants approach. Practitioner-informed evidence is the missing link in the evidence debate and provides the links between evidence and its translation to practice. New models of health promotion service

  15. Promoting Visualization Skills through Deconstruction Using Physical Models and a Visualization Activity Intervention

    Science.gov (United States)

    Schiltz, Holly Kristine

    Visualization skills are important in learning chemistry, as these skills have been shown to correlate to high ability in problem solving. Students' understanding of visual information and their problem-solving processes may only ever be accessed indirectly: verbalization, gestures, drawings, etc. In this research, deconstruction of complex visual concepts was aligned with the promotion of students' verbalization of visualized ideas to teach students to solve complex visual tasks independently. All instructional tools and teaching methods were developed in accordance with the principles of the theoretical framework, the Modeling Theory of Learning: deconstruction of visual representations into model components, comparisons to reality, and recognition of students' their problemsolving strategies. Three physical model systems were designed to provide students with visual and tangible representations of chemical concepts. The Permanent Reflection Plane Demonstration provided visual indicators that students used to support or invalidate the presence of a reflection plane. The 3-D Coordinate Axis system provided an environment that allowed students to visualize and physically enact symmetry operations in a relevant molecular context. The Proper Rotation Axis system was designed to provide a physical and visual frame of reference to showcase multiple symmetry elements that students must identify in a molecular model. Focus groups of students taking Inorganic chemistry working with the physical model systems demonstrated difficulty documenting and verbalizing processes and descriptions of visual concepts. Frequently asked student questions were classified, but students also interacted with visual information through gestures and model manipulations. In an effort to characterize how much students used visualization during lecture or recitation, we developed observation rubrics to gather information about students' visualization artifacts and examined the effect instructors

  16. Computing DNA duplex instability profiles efficiently with a two-state model: trends of promoters and binding sites

    Directory of Open Access Journals (Sweden)

    Rapti Zoi

    2010-12-01

    Full Text Available Abstract Background DNA instability profiles have been used recently for predicting the transcriptional start site and the location of core promoters, and to gain insight into promoter action. It was also shown that the use of these profiles can significantly improve the performance of motif finding programs. Results In this work we introduce a new method for computing DNA instability profiles. The model that we use is a modified Ising-type model and it is implemented via statistical mechanics. Our linear time algorithm computes the profile of a 10,000 base-pair long sequence in less than one second. The method we use also allows the computation of the probability that several consecutive bases are unpaired simultaneously. This is a feature that is not available in other linear-time algorithms. We use the model to compare the thermodynamic trends of promoter sequences of several genomes. In addition, we report results that associate the location of local extrema in the instability profiles with the presence of core promoter elements at these locations and with the location of the transcription start sites (TSS. We also analyzed the instability scores of binding sites of several human core promoter elements. We show that the instability scores of functional binding sites of a given core promoter element are significantly different than the scores of sites with the same motif occurring outside the functional range (relative to the TSS. Conclusions The time efficiency of the algorithm and its genome-wide applications makes this work of broad interest to scientists interested in transcriptional regulation, motif discovery, and comparative genomics.

  17. Due process model of procedural justice in performance appraisal: promotion versus termination scenarios.

    Science.gov (United States)

    Kataoka, Heloneida C; Cole, Nina D; Flint, Douglas A

    2006-12-01

    In a laboratory study, 318 student participants (148 male, 169 female, and one who did not report sex; M age 25.0, SD = 6.0) in introductory organizational behavior classes responded to scenarios in which performance appraisal resulted in either employee promotion or termination. Each scenario had varying levels of three procedural justice criteria for performance appraisal. For both promotion and termination outcomes, analysis showed that, as the number of criteria increased, perceptions of procedural fairness increased. A comparison between the two outcomes showed that perceptions of fairness were significantly stronger for the promotion outcome than for termination.

  18. The exaptation of manual dexterity for articulate speech: an electromyogram investigation.

    Science.gov (United States)

    Higginbotham, David R; Isaak, Matthew I; Domingue, James N

    2008-04-01

    Electromyogram recordings revealed a concurrent contraction of the orbicularis oris, the primary articulator for bilabial stops, when participants executed a precision grip contracting the abductor pollicis brevis, a point motor act contracting the extensor indicis proprius or a curl motor act contracting the flexor sublimis digitorum (FDS). In contrast, the concurrent contraction of several facial muscles not directly involved in labial articulation was not observed during these acts. The results converge both with observations of sympathetic hand and mouth activity among nonhuman primates and prelinguistic human infants and with demonstrations of the influence of grasping on labial articulation in adult humans (e.g., Gentilucci et al., J Neurophysiol 86, 1685-1699, 2001). The findings are also consistent with theories suggesting the transition from gestural to verbal, articulate communication systems may be subserved by the properties of the human equivalent of monkey F5 mirror and canonical neurons located in Broca's area.

  19. Direct and indirect measures of speech articulator motions using low power EM sensors

    Energy Technology Data Exchange (ETDEWEB)

    Barnes, T; Burnett, G; Gable, T; Holzrichter, J F; Ng, L

    1999-05-12

    Low power Electromagnetic (EM) Wave sensors can measure general properties of human speech articulator motions, as speech is produced. See Holzrichter, Burnett, Ng, and Lea, J.Acoust.Soc.Am. 103 (1) 622 (1998). Experiments have demonstrated extremely accurate pitch measurements (< 1 Hz per pitch cycle) and accurate onset of voiced speech. Recent measurements of pressure-induced tracheal motions enable very good spectra and amplitude estimates of a voiced excitation function. The use of the measured excitation functions and pitch synchronous processing enable the determination of each pitch cycle of an accurate transfer function and, indirectly, of the corresponding articulator motions. In addition, direct measurements have been made of EM wave reflections from articulator interfaces, including jaw, tongue, and palate, simultaneously with acoustic and glottal open/close signals. While several types of EM sensors are suitable for speech articulator measurements, the homodyne sensor has been found to provide good spatial and temporal resolution for several applications.

  20. Articulating the signs of danger: lay experiences of post-Chernobyl radiation risks and effects.

    Science.gov (United States)

    Kuchinskaya, Olga

    2011-05-01

    This essay examines lay experiences of radiation--the hazard imperceptible with unaided senses--and how these experiences are shaped. Analysis is conducted on the basis of participant observation and interviews in Belarusian rural areas affected after the 1986 Chernobyl nuclear accident. I argue that radiation risks and health effects are not always obvious or immediately observable for those experiencing them, and they should be articulated. The paper compares various opportunities for articulation, including the context of radiological testing and administrative contexts, and describes the kinds of articulations they make possible. I conclude that limited opportunities for articulation result in limited lay recognition of radioactive contamination and their own health effects. The analysis implies that affected lay populations cannot always be assumed to be the most risk-conscious and hold special knowledge about radiation effects independently of scientific and administrative definitions of it.

  1. Changes in vowel articulation with subthalamic nucleus deep brain stimulation in dysarthric speakers with Parkinson's disease

    National Research Council Canada - National Science Library

    Martel Sauvageau, Vincent; Macoir, Joël; Langlois, Mélanie; Prud'Homme, Michel; Cantin, Léo; Roy, Johanna-Pascale

    2014-01-01

    ... (1 hour after DBS was turned off). Vowel articulation was compared ON-simulation versus OFF-stimulation using acoustic vowel space and formant centralization ratio, calculated with the first (F1...

  2. The cognitive ergonomics and the articulation of the functions of industrial products.

    Science.gov (United States)

    Oliveira, Sabrina Talita; Heemann, Adriano

    2012-01-01

    The sustainable development is a challenge to all areas of knowledge. In the field of design, it motivates an enhanced discussion about the functions of systems, products and services. Accordingly, this paper presents a theoretical contribution to the sustainable articulation of the functions of industrial products from principles of cognitive ergonomics. This paper is based on an exploratory literature about the functions of industrial products and further study of the relationship between man and object of Cognitive Ergonomics, specifically linked the aesthetic perception and symbolic. Presents qualitative results of this correlation, which indicates the feasibility of a better articulation in product development. The paper argues that in the practical field of design, the best articulation of the functions may influence the effectiveness of product performance in its relationship with the user. Already, on theoretical grounds, this new articulation can help designers to understand the nature of the transdisciplinary functions and the insights into product design.

  3. Demand articulation in emerging technologies: Intermediary user organisations as co-producers?

    NARCIS (Netherlands)

    Boon, Wouter P.C.; Moors, Ellen H.M.; Kuhlmann, Stefan; Smits, Ruud E.H.M.

    2010-01-01

    User involvement is assumed to be beneficial to innovation processes. Intermediary user organisations contribute to articulating societal demands for innovations. However, the learning processes inside these organisations are still not understood well. Therefore, this paper empirically investigates

  4. Demand articulation in emerging technologies: intermediary user organizations as co-producers?

    NARCIS (Netherlands)

    Boon, W.P.C.; Moors, E.H.M.; Kuhlmann, S.; Smits, R.E.H.M.

    2011-01-01

    User involvement is assumed to be beneficial to innovation processes. Intermediary user organisations contribute to articulating societal demands for innovations. However, the learning processes inside these organisations are still not understood well. Therefore, this paper empirically investigates

  5. A model to explain plant growth promotion traits: a multivariate analysis of 2,211 bacterial isolates.

    Directory of Open Access Journals (Sweden)

    Pedro Beschoren da Costa

    Full Text Available Plant growth-promoting bacteria can greatly assist sustainable farming by improving plant health and biomass while reducing fertilizer use. The plant-microorganism-environment interaction is an open and complex system, and despite the active research in the area, patterns in root ecology are elusive. Here, we simultaneously analyzed the plant growth-promoting bacteria datasets from seven independent studies that shared a methodology for bioprospection and phenotype screening. The soil richness of the isolate's origin was classified by a Principal Component Analysis. A Categorical Principal Component Analysis was used to classify the soil richness according to isolate's indolic compound production, siderophores production and phosphate solubilization abilities, and bacterial genera composition. Multiple patterns and relationships were found and verified with nonparametric hypothesis testing. Including niche colonization in the analysis, we proposed a model to explain the expression of bacterial plant growth-promoting traits according to the soil nutritional status. Our model shows that plants favor interaction with growth hormone producers under rich nutrient conditions but favor nutrient solubilizers under poor conditions. We also performed several comparisons among the different genera, highlighting interesting ecological interactions and limitations. Our model could be used to direct plant growth-promoting bacteria bioprospection and metagenomic sampling.

  6. A model to explain plant growth promotion traits: a multivariate analysis of 2,211 bacterial isolates.

    Science.gov (United States)

    da Costa, Pedro Beschoren; Granada, Camille E; Ambrosini, Adriana; Moreira, Fernanda; de Souza, Rocheli; dos Passos, João Frederico M; Arruda, Letícia; Passaglia, Luciane M P

    2014-01-01

    Plant growth-promoting bacteria can greatly assist sustainable farming by improving plant health and biomass while reducing fertilizer use. The plant-microorganism-environment interaction is an open and complex system, and despite the active research in the area, patterns in root ecology are elusive. Here, we simultaneously analyzed the plant growth-promoting bacteria datasets from seven independent studies that shared a methodology for bioprospection and phenotype screening. The soil richness of the isolate's origin was classified by a Principal Component Analysis. A Categorical Principal Component Analysis was used to classify the soil richness according to isolate's indolic compound production, siderophores production and phosphate solubilization abilities, and bacterial genera composition. Multiple patterns and relationships were found and verified with nonparametric hypothesis testing. Including niche colonization in the analysis, we proposed a model to explain the expression of bacterial plant growth-promoting traits according to the soil nutritional status. Our model shows that plants favor interaction with growth hormone producers under rich nutrient conditions but favor nutrient solubilizers under poor conditions. We also performed several comparisons among the different genera, highlighting interesting ecological interactions and limitations. Our model could be used to direct plant growth-promoting bacteria bioprospection and metagenomic sampling.

  7. Linking Colleague Support to Employees' Promotive Voice: A Moderated Mediation Model.

    Science.gov (United States)

    Xie, Xiao-Yun; Ling, Chu-Ding; Mo, Shen-Jiang; Luan, Kun

    2015-01-01

    Promotive voice is essential for improving team and organization performance. Yet in the current literature, less was known regarding the psychological reasons why people engage in promotive voice. Through the lens of social exchange, we proposed that employees who received support from colleagues may develop higher level of felt obligation for constructive change which leads to promotive voice. Analyses of multi-source data from 51 cross-functional sources (51 team supervisors and 162 employees) showed that employees' felt obligation for constructive change positively mediates the relationship between colleague support and promotive voice behavior. Moreover, the impact of colleague support on felt obligation for constructive change is stronger when there is a low level of subgroup formation in the team. Theoretical and practical implications of these findings are discussed.

  8. Feedback models allowing estimation of thresholds for self-promoting body weight gain

    DEFF Research Database (Denmark)

    Christiansen, Edmund; Swann, Andrew; Sørensen, Thorkild I. A.

    2008-01-01

    . The difference between the two situations is typically an energy imbalance of about 1% over a long period of time. THEORY: Weight gain increases basal metabolic rate. Weight gain is often associated with a decrease in physical activity, although not to such an extent that it prevents an increase in total energy...... expenditure and energy intake. Dependent on the precise balance between these effects of weight gain, they may make the body weight unstable and tend to further promote weight gain. With the aim of identifying the thresholds beyond which such self-promoting weight gain may take place, we develop a simple...... cases do they take values that make weight gain self-promoting. RESULTS: We determine the quantitative conditions under which body weight gain becomes self-promoting. We find that these conditions can easily be met, and that they are so small that they are not observable with currently available...

  9. Adolescent idiopathic scoliosis screening for school, community, and clinical health promotion practice utilizing the PRECEDE-PROCEED model

    Directory of Open Access Journals (Sweden)

    Wyatt Lawrence A

    2005-11-01

    Full Text Available Abstract Background Screening for adolescent idiopathic scoliosis (AIS is a commonly performed procedure for school children during the high risk years. The PRECEDE-PROCEDE (PP model is a health promotion planning model that has not been utilized for the clinical diagnosis of AIS. The purpose of this research is to study AIS in the school age population using the PP model and its relevance for community, school, and clinical health promotion. Methods MEDLINE was utilized to locate AIS data. Studies were screened for relevance and applicability under the auspices of the PP model. Where data was unavailable, expert opinion was utilized based on consensus. Results The social assessment of quality of life is limited with few studies approaching the long-term effects of AIS. Epidemiologically, AIS is the most common form of scoliosis and leading orthopedic problem in children. Behavioral/environmental studies focus on discovering etiologic relationships yet this data is confounded because AIS is not a behavioral. Illness and parenting health behaviors can be appreciated. The educational diagnosis is confounded because AIS is an orthopedic disorder and not behavioral. The administration/policy diagnosis is hindered in that scoliosis screening programs are not considered cost-effective. Policies are determined in some schools because 26 states mandate school scoliosis screening. There exists potential error with the Adam's test. The most widely used measure in the PP model, the Health Belief Model, has not been utilized in any AIS research. Conclusion The PP model is a useful tool for a comprehensive study of a particular health concern. This research showed where gaps in AIS research exist suggesting that there may be problems to the implementation of school screening. Until research disparities are filled, implementation of AIS screening by school, community, and clinical health promotion will be compromised. Lack of data and perceived importance by

  10. Spinal traction promotes molecular transportation in a simulated degenerative intervertebral disc model.

    Science.gov (United States)

    Kuo, Ya-Wen; Hsu, Yu-Chun; Chuang, I-Ting; Chao, Pen-Hsiu Grace; Wang, Jaw-Lin

    2014-04-20

    Biomechanical experiment using an in situ porcine model. To find the effect of traction treatment on annulus microstructure, molecular convection, and cell viability of degraded discs. Spinal traction is a conservative treatment for disc disorders. The recognized biomechanical benefits include disc height recovery, foramen enlargement, and intradiscal pressure reduction. However, the influence of traction treatment on annulus microstructure, molecular transportation, and cell viability of degraded discs has not been fully investigated. A total of 48 thoracic discs were dissected from 8 porcine spines (140 kg, 6-month old) within 4 hours after killing them and then divided into 3 groups: intact, degraded without traction, and degraded with traction. Each disc was incubated in a whole-organ culture system and subjected to diurnal loadings for 7 days. Except for the intact group, discs were degraded with 0.5 mL of trypsin on day 1 and a 5-hour fatigue loading on day 2. From day 4 to day 6, half of the degraded discs received a 30-minute traction treatment per day (traction force: 20 kg; loading: unloading = 30 s: 10 s). By the end of the incubation, the discs were inspected for disc height loss, annulus microstructure, molecular (fluorescein sodium) intensity, and cell viability. Collagen fibers were crimped and delaminated, whereas the pores were occluded in the annulus fibrosus of the degraded discs. Molecular transportation and cell viability of the discs decreased after matrix degradation. With traction treatment, straightened collagen fibers increased within the degraded annulus fibrosus, and the annulus pores were less occluded. Both molecular transportation and cell viability increased, but not to the intact level. Traction treatment is effective in enhancing nutrition supply and promoting disc cell proliferation of the degraded discs. N/A.

  11. Tissue engineering chamber promotes adipose tissue regeneration in adipose tissue engineering models through induced aseptic inflammation.

    Science.gov (United States)

    Peng, Zhangsong; Dong, Ziqing; Chang, Qiang; Zhan, Weiqing; Zeng, Zhaowei; Zhang, Shengchang; Lu, Feng

    2014-11-01

    Tissue engineering chamber (TEC) makes it possible to generate significant amounts of mature, vascularized, stable, and transferable adipose tissue. However, little is known about the role of the chamber in tissue engineering. Therefore, to investigate the role of inflammatory response and the change in mechanotransduction started by TEC after implantation, we placed a unique TEC model on the surface of the groin fat pads in rats to study the expression of cytokines and tissue development in the TEC. The number of infiltrating cells was counted, and vascular endothelial growth factor (VEGF) and monocyte chemotactic protein-1 (MCP-1) expression levels in the chamber at multiple time points postimplantation were analyzed by enzyme-linked immunosorbent assay. Tissue samples were collected at various time points and labeled for specific cell populations. The result showed that new adipose tissue formed in the chamber at day 60. Also, the expression of MCP-1 and VEGF in the chamber decreased slightly from an early stage as well as the number of the infiltrating cells. A large number of CD34+/perilipin- perivascular cells could be detected at day 30. Also, the CD34+/perilipin+ adipose precursor cell numbers increased sharply by day 45 and then decreased by day 60. CD34-/perilipin+ mature adipocytes were hard to detect in the chamber content at day 30, but their number increased and then peaked at day 60. Ki67-positive cells could be found near blood vessels and their number decreased sharply over time. Masson's trichrome showed that collagen was the dominant component of the chamber content at early stage and was replaced by newly formed small adipocytes over time. Our findings suggested that the TEC implantation could promote the proliferation of adipose precursor cells derived from local adipose tissue, increase angiogenesis, and finally lead to spontaneous adipogenesis by inducing aseptic inflammation and changing local mechanotransduction.

  12. GROSS MORPHOLOGY OF THE HIP ARTICULATION OF BUFFALO CALVES (BUBALUS BUBALIS)

    OpenAIRE

    2014-01-01

    Back ground: The vulnerability of the buffalo to the luxation of the hip articulation previous to and during parturition encouraged the investigation in this species. The literature reviewed did not reveal complete anatomical descriptions of the coxofemoral articulation of buffalo. Hence the study was undertaken. Purpose: to study the different anatomical aspects of the hip joint which are specific to buffaloes. Methods and Results: A total number of fifteen hip joints of buffalo cal...

  13. Design of an articulated manipulator for enhanced dexterity in minimally invasive surgery

    OpenAIRE

    Ray, Jerry DeWane, II

    1996-01-01

    Approved for public release; distribution is unlimited. A current limitation in minimally invasive surgical (MIS) procedures is the lack of an articulated mechanism which will provide dexterity inside the torso while supporting a surgical tool. The tool could be a pair of scissors or an optical device such as a camera, or both. To overcome this limitation we have designed an Articulated Manipulator for Minimally Invasive Surgery (AMMIS). The AMMIS is expected to provide surgeons with impro...

  14. Comparison of mechanical properties of silicone and PVC (polyvinylchloride) cosmetic gloves for articulating hand prostheses

    OpenAIRE

    Gerwin Smit, MSc; Dick H. Plettenburg, MSc, PhD

    2013-01-01

    Current articulating electric and body-powered hands have a lower pinch force (15–34 N) than electric hands with stiff fingers (55–100 N). The cosmetic glove, which covers a hand prosthesis, negatively affects the mechanical efficiency of a prosthesis. The goal of this study is to mechanically compare polyvinylchloride (PVC) and silicone cosmetic gloves and quantify the stiffness of the finger joints, the required actuation energy, and the energy dissipation during joint articulation. Six cos...

  15. Direct transfer of the position of digitized casts to a virtual articulator.

    Science.gov (United States)

    Solaberrieta, Eneko; Mínguez, Rikardo; Barrenetxea, Lander; Etxaniz, Olatz

    2013-06-01

    This article describes a digital technique to transfer the location of digitized casts obtained directly from the patient to a virtual articulator (digital/virtual facebow transfer). The primary advantage of this technique is that it allows the dentist and the dental laboratory technician to work in a fully digital environment without having to mount stone casts on a physical articulator. This results in a significant time reduction and a higher degree of accuracy in the cast location.

  16. THE ARTICULATION STATUS IN PRE-SCHOOL CHILDREN WITH IMPARED HEARING ECOMPRASSED BY REHABILITATION TREATMENT

    Directory of Open Access Journals (Sweden)

    Veneta TRAJKOVSKA

    2000-06-01

    Full Text Available The main goal of this research is evaluation of the progress of articulation towards the particular group of voices of the preschool aged children with hearing impairment, which are included in rehabilitation treatment. The research explores the impact of the general factors (degree of the hearing impairment, age of the examinees, etiological factor of the hearing impairment, and duration of the treatment, which contributes in the progress of articulation.

  17. Production and perception of legato, portato and staccato articulation in saxophone playing

    Directory of Open Access Journals (Sweden)

    Alex eHofmann

    2014-07-01

    Full Text Available This paper investigates the production and perception of different articulation techniques on the saxophone. In a production experiment, two melodies were recorded that required different effectors to play the tones (tongue actions alone, finger actions alone, combined tongue and finger actions at three different tempi. A sensor saxophone reed was developed to monitor tongue-reed interactions during performance. At the slow tempo condition, combined tongue-finger actions showed improved timing, compared to the timing of the tongue alone. This observation supports the multiple timer hypothesis where the tongue's timekeeper benefits from a coupling to the timekeeper of the fingers. At the fast tempo condition, finger alone actions were less precise than the tongue alone and combined tongue-finger actions led to more variable timing. This suggests that the finger actions have a dominant influence on the overall timing of saxophone performance. In a listening experiment we investigated whether motor expertise in music performance influences the perception of articulation techniques in saxophone performance. Participants with different backgrounds in music making (saxophonists, musicians not playing the saxophone, and non-musicians attended an AB-X listening test. They had to discriminate between saxophone phrases played with different articulation techniques (legato, portato, staccato. Participants across all three groups discriminated the sound of staccato articulation well from the sound of portato articulation and legato articulation. Errors occurred across all groups of listeners when legato articulation (no tonguing and portato articulation (soft tonguing had to be discriminated. Saxophonists' results were superior compared to the results of the other two groups, suggesting that expertise in saxophone playing facilitated the discrimination task.

  18. A new method for screening potential sII and sH hydrogen clathrate hydrate promoters with model potentials.

    Science.gov (United States)

    Frankcombe, Terry J; Kroes, Geert-Jan

    2011-08-01

    A new predictive computational method for classifying clathrate hydrate promoter molecules is presented, based on the interaction energies between potential promoters and the water networks of sII and sH clathrates. The motivation for this work is identifying promoters for storing hydrogen compactly in clathrate hydrates. As a first step towards achieving this goal, we have developed a general method aimed at distinguishing between molecules that form sII clathrate hydrates and molecules that can-together with a weakly interacting help gas-form sH clathrate hydrates. The new computational method calculates differences in estimated formation energies of the sII and the sH clathrate hydrate. Model interaction potentials have been used, including the electrostatic interactions with newly calculated partial charges for all the considered potential promoter molecules. The methodology can discriminate between the clathrate structure types (sII or sH) formed by each potential promoter with good selectivity, i.e., better than achieved with a simple van der Waals diameter criterion.

  19. Utilizing the Health Promotion Model to predict oral health behaviors in the students of Islamic Azad University of Sabzevar(2008

    Directory of Open Access Journals (Sweden)

    Mehri A.

    2009-08-01

    Full Text Available "nBackground and Aim: It is necessary to assess health status for designing and programming about oral health behaviors. In this study the Effectiveness of Health Promotion Model in Predicting oral health among the Students of Islamic Azad University of Sabzevar was examined. "nMaterials and Methods: This was a descriptive-analytic, cross-sectional study. A random (stratified sample of 250 university students in Islamic Azad university of Sabzevar, participated in the study. Appropriate instruments were designed to measure the variables of interest based on health promotion model. Reliability and validity of the instruments were examined by a panel of experts and cronbach alpha (N=30,α=0.65-0.81 respectively. The data were analyzed by SPSS 11.5 Statistical Software using Spearman Coefficient, Path analysis based on regression and ANOVA. "nResults: The mean of oral health behaviors among students was moderate (19.17±3.91 out of total 36.Statistically significant differences were found in oral health behaviors and the model variables by parent education (P<0.05. The results showed that the model variables were related to oral health behaviors of the students (P<0.05.Self-efficacy,interpersonal influences,positive emotion, perceived barriers and commitment to plan of action as variables of HPM model explained 29% of oral health behaviors among subjects within which self-efficacy was the strongest predictorβ=0.252. "nConclusion: Although the mean of oral health behaviors was moderate among the subjects, but it should be promoted because of their great importance on the individuals' health. It was concluded that the Health Promotion Model may be used as a framework for planning intervention programs in an attempt to improve the oral health behaviors of the university students.

  20. Folic acid supplementation promotes mammary tumor progression in a rat model.

    Science.gov (United States)

    Deghan Manshadi, Shaidah; Ishiguro, Lisa; Sohn, Kyoung-Jin; Medline, Alan; Renlund, Richard; Croxford, Ruth; Kim, Young-In

    2014-01-01

    Folic acid supplementation may prevent the development of cancer in normal tissues but may promote the progression of established (pre)neoplastic lesions. However, whether or not folic acid supplementation can promote the progression of established (pre)neoplastic mammary lesions is unknown. This is a critically important issue because breast cancer patients and survivors in North America are likely exposed to high levels of folic acid owing to folic acid fortification and widespread supplemental use after cancer diagnosis. We investigated whether folic acid supplementation can promote the progression of established mammary tumors. Female Sprague-Dawley rats were placed on a control diet and mammary tumors were initiated with 7,12-dimethylbenza[a]anthracene at puberty. When the sentinel tumor reached a predefined size, rats were randomized to receive a diet containing the control, 2.5x, 4x, or 5x supplemental levels of folic acid for up to 12 weeks. The sentinel mammary tumor growth was monitored weekly. At necropsy, the sentinel and all other mammary tumors were analyzed histologically. The effect of folic acid supplementation on the expression of proteins involved in proliferation, apoptosis, and mammary tumorigenesis was determined in representative sentinel adenocarcinomas. Although no clear dose-response relationship was observed, folic acid supplementation significantly promoted the progression of the sentinel mammary tumors and was associated with significantly higher sentinel mammary tumor weight and volume compared with the control diet. Furthermore, folic acid supplementation was associated with significantly higher weight and volume of all mammary tumors. The most significant and consistent mammary tumor-promoting effect was observed with the 2.5x supplemental level of folic acid. Folic acid supplementation was also associated with an increased expression of BAX, PARP, and HER2. Our data suggest that folic acid supplementation may promote the progression

  1. Model of facilitation of emotional intelligence to promote wholeness of neophyte critical care nurses in South Africa

    Directory of Open Access Journals (Sweden)

    A. Towell

    2015-06-01

    Full Text Available This study was undertaken in order to develop a model of facilitation of emotional intelligence to promote wholeness in neophyte critical care nurses in South Africa. A theory-generative, explorative, descriptive, contextual research design was used. The model was developed utilising the four steps of theory generation as proposed by Dickoff, James, and Wiedenbach (1968, Chinn and Kramer (2011 and Walker and Avant (2011. Step one dealt with the empirical phase in which the concepts were distilled. The facilitation of inherent affective and mental resourcefulness and resilience was the main concept of the model. Step two comprised the definition and classification of central and related concepts. Step three provides a description of the model. The model operates in three phases namely the dependent phase, partially dependent phase and the independent phase. Step four entailed the description of guidelines for operationalizing the model. During the three phases of the model a new nurse who starts to work in critical care moves from a latent ability to develop an inherent affective and mental resourcefulness and resilience to a state of developing an inherent affective and mental resourcefulness and resilience. This model provides a structured framework for the facilitation of emotional intelligence (EI to promote wholeness in nurses who commence to work in critical care units.

  2. A closed-loop dynamic simulation-based design method for articulated heavy vehicles with active trailer steering systems

    Science.gov (United States)

    Manjurul Islam, Md.; Ding, Xuejun; He, Yuping

    2012-05-01

    This paper presents a closed-loop dynamic simulation-based design method for articulated heavy vehicles (AHVs) with active trailer steering (ATS) systems. AHVs have poor manoeuvrability at low speeds and exhibit low lateral stability at high speeds. From the design point of view, there exists a trade-off relationship between AHVs' manoeuvrability and stability. For example, fewer articulation points and longer wheelbases will improve high-speed lateral stability, but they will degrade low-speed manoeuvrability. To tackle this conflicting design problem, a systematic method is proposed for the design of AHVs with ATS systems. In order to evaluate vehicle performance measures under a well-defined testing manoeuvre, a driver model is introduced and it 'drivers' the vehicle model to follow a prescribed route at a given speed. Considering the interactions between the mechanical trailer and the ATS system, the proposed design method simultaneously optimises the active design variables of the controllers and passive design variables of the trailer in a single design loop (SDL). Through the design optimisation of an ATS system for an AHV with a truck and a drawbar trailer combination, this SDL method is compared against a published two design loop method. The benchmark investigation shows that the former can determine better trade-off design solutions than those derived by the latter. This SDL method provides an effective approach to automatically implement the design synthesis of AHVs with ATS systems.

  3. Relevance of the mouse skin initiation-promotion model for the classification of carcinogenic substances encountered at the workplace.

    Science.gov (United States)

    Schwarz, Michael; Thielmann, Heinz W; Meischner, Veronika; Fartasch, Manigé

    2015-06-01

    The Permanent Senate Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area (MAK Commission of the Deutsche Forschungsgemeinschaft) evaluates chemical substances using scientific criteria to prevent adverse effects on health at the work place. As part of this task there is a need to evaluate tumor promoting activity of chemicals (enhancement of formation of squamous cell carcinomas via premalignant papillomas) obtained from two-stage initiation/promotion experiments using the mouse skin model. In the present communication we address this issue by comparing responses seen in mouse skin with those in humans. We conclude that tumor promotional effects seen in such animal models be carefully analyzed on a case by case basis. Substances that elicit a rather non-specific effect that is restricted to the high dose range are considered to be irrelevant to humans and thus do not require classification as carcinogens. In contrast, substances that might have both a mode of action and a potency similar to the specific effects seen with TPA (12-O-tetradecanoylphorbol-13-acetate), the prototype tumor promoter in mouse skin, which triggers receptor-mediated signal cascades in the very low dose range, have to be classified in a category for carcinogens.

  4. [Subtainable health promotion via organisational development--a model project for teachers in professional training schools].

    Science.gov (United States)

    Schumacher, L; Nieskens, B; Bräuer, H; Sieland, B

    2005-02-01

    The goal of this project is the development, implementation and evaluation of a concept designed for sustainable health promotion among occupational and trade school teachers. We assume that for sustainable health promotion -- along with a behavioral prevention program -- a change is necessary in the structure, as well as, the working and communication processes within schools. The realization of early teacher participation and self regulated cooperative groups initiates comprehensive and goal-oriented developmental processes in the project schools. The organizational development process was accomplished in the following way: At the beginning we conducted a diagnosis of school-specific and individual health risks and the resources available to the project schools. The results were reported for both the individual and for the teacher group. This was intended to clarify the potential for improvement and, thus, strengthen the teachers' motivation toward processes of change. Following the diagnosis, the teachers chose areas of stress-related strain and then worked in groups to develop and implement behaviour and working condition-oriented intervention strategies for health promotion. The diagnosis results confirm the necessity of school-specific health promotion: the schools demonstrate very different demand and resource profiles. Furthermore, is has become evident that the central success factor for health promotion in schools is the teachers' willingness for change. The individual and group reports of the diagnosis results seem to have made clear how essential individual and organisational changes are.

  5. [Property analysis of the finals mispronunciation in Chinese-speaking children with functional articulation disorder].

    Science.gov (United States)

    Du, Z H; Peng, B W; Li, X J; Huang, Z F; Yang, S Y; Chen, Z M

    2016-10-02

    Objective: To characterize the finals mispronunciation in Chinese-speaking children with functional articulation disorder (FAD), in order to promote the standardized diagnosis. Method: A retrospective study was conducted. From January to December 2013, 90 FAD children, diagnosed by Dysarthria Rating Scale and Mandarin Finals scale, were included in this study. Among them, 22 were found to have finals mispronunciation; the average age was (6.56±0.26) years. According to the finals classification, six different finals (simple finals, front vowel compound finals, central vowel compound finals, back vowel compound finals, anterior nasal finals, and posterior nasal finals) were defined; the produced sound samples of those subjects were analyzed. Result: In all these children, 22 of 90 (24%) were found having finals mispronunciation, the occurring rates of which with omission and substitution errors were: 3% (4/132) for simple finals, 30% (26/88) for front vowel compound finals, 26% (23/88) for central vowel compound finals, 7% (8/110) for back vowel compound finals, 73%(128/176) for anterior nasal finals and 73% (112/154) for posterior nasal finals, respectively. In omission and substitution errors, the ratios of the finals above were 50% (150/301), 3% (10/301), 5% (14/301), 36% (107/301), 2% (5/301) and 5% (15/301), respectively. The most frequently occurred mispronunciation were omission, substitution and distortion, with rates of 37% (273/748), 4% (28/748) and 8% (61/748), respectively. Conclusion: The FAD children have remarkable mispronunciation of finals. Omission is the main error. The nasal finals are the most commonly involved, followed by front vowel and central vowel compound finals. The simple finals and the back vowel compound finals are most commonly produced in omission and substitution. These finals production features should be considered when making and implementing rehabilitation programs.

  6. Modeling of the Institutional System of Enterpreneurship Promotion: the Case of Lithuania

    Directory of Open Access Journals (Sweden)

    Gediminas Pauliukevicius

    2013-09-01

    Full Text Available The purpose of the article is to review the institutional system of entrepreneurship promotion that exists in Lithuania and to offer guidelines to improve it. The research results show that the unified institutional system of entrepreneurship promotion in Lithuania does not present: responsible institutions coordinate single measures and their implementation, but do not follow long-term general strategy. According to research findings, in order to improve the entrepreneurship promotion system of Lithuania there is a need to create the main institutional system out of responsable ministries (the Ministry of Education and Science, the Ministry of Economy, the Ministry of Agriculture, the Ministry of Social Security and Labour and define the boundaries of their responsibilities.

  7. Promoter or enhancer, what's the difference? Deconstruction of established distinctions and presentation of a unifying model

    DEFF Research Database (Denmark)

    Andersson, Robin

    2015-01-01

    Gene transcription is strictly controlled by the interplay of regulatory events at gene promoters and gene-distal regulatory elements called enhancers. Despite extensive studies of enhancers, we still have a very limited understanding of their mechanisms of action and their restricted spatio......-temporal activities. A better understanding would ultimately lead to fundamental insights into the control of gene transcription and the action of regulatory genetic variants involved in disease. Here, I review and discuss pros and cons of state-of-the-art genomics methods to localize and infer the activity...... of enhancers. Among the different approaches, profiling of enhancer RNAs yields the highest specificity and may be superior in detecting in vivo activity. I discuss their apparent similarities to promoters, which challenge the established view of enhancers and promoters as distinct entities, and present...

  8. Scabies mites alter the skin microbiome and promote growth of opportunistic pathogens in a porcine model.

    Directory of Open Access Journals (Sweden)

    Pearl M Swe

    Full Text Available BACKGROUND: The resident skin microbiota plays an important role in restricting pathogenic bacteria, thereby protecting the host. Scabies mites (Sarcoptes scabiei are thought to promote bacterial infections by breaching the skin barrier and excreting molecules that inhibit host innate immune responses. Epidemiological studies in humans confirm increased incidence of impetigo, generally caused by Staphylococcus aureus and Streptococcus pyogenes, secondary to the epidermal infestation with the parasitic mite. It is therefore possible that mite infestation could alter the healthy skin microbiota making way for the opportunistic pathogens. A longitudinal study to test this hypothesis in humans is near impossible due to ethical reasons. In a porcine model we generated scabies infestations closely resembling the disease manifestation in humans and investigated the scabies associated changes in the skin microbiota over the course of a mite infestation. METHODOLOGY/PRINCIPAL FINDINGS: In a 21 week trial, skin scrapings were collected from pigs infected with S. scabies var. suis and scabies-free control animals. A total of 96 skin scrapings were collected before, during infection and after acaricide treatment, and analyzed by bacterial 16S rDNA tag-encoded FLX-titanium amplicon pyrosequencing. We found significant changes in the epidermal microbiota, in particular a dramatic increase in Staphylococcus correlating with the onset of mite infestation in animals challenged with scabies mites. This increase persisted beyond treatment from mite infection and healing of skin. Furthermore, the staphylococci population shifted from the commensal S. hominis on the healthy skin prior to scabies mite challenge to S. chromogenes, which is increasingly recognized as being pathogenic, coinciding with scabies infection in pigs. In contrast, all animals in the scabies-free cohort remained relatively free of Staphylococcus throughout the trial. CONCLUSIONS

  9. Thrombin related peptide TP508 promoted fracture repair in a mouse high energy fracture model

    Directory of Open Access Journals (Sweden)

    Pan Xiao-Hua

    2009-01-01

    Full Text Available Abstract Background Thrombin related peptide (TP508 is a 23 amino-acid synthetic peptide that represents a portion of the receptor-binding domain of thrombin molecule. Previous studies have shown that TP508 can accelerate musculoskeletal tissue repair including fracture healing. Objectives The aim of this study was to investigate the effect of TP508 on fracture healing in a murine fracture model representing high energy fracture situation. Methods Eighty CD 1 mice underwent controlled quadriceps muscle crush and open transverse mid diaphyseal femoral fracture that was then fixed with an external fixator. Animals were randomised into four groups to receive an intra-operative dose of either 100 μg TP508 into the fracture gap; 100 μg TP508 into the surrounding damaged muscle tissues; 10 μg TP508 into the fracture gap, or control equal amount of saline into the fracture gap. Radiographic assessment was performed weekly for 5 weeks; histological analysis was at 3 and 5 weeks post fracture and biomechanical testing of the fractured bone was performed at 5 weeks post fracture. Results Mechanical testing data showed that the fracture stiffness was significantly higher in the group receiving 100 μg TP508 into the fracture gap than other groups. Histological and radiographic analysis revealed a trend of increase in bone formation in the 100 μg TP508 injected into the fracture gap group compared to the saline control group. It was noted that the scar tissues was significantly less in Group II comparing with the saline control group and there was increased blood vessel formation in the crushed muscles and fracture gap areas in the groups receiving TP508 comparing to the saline control group. Conclusion The results from this study demonstrated the use of thrombin related peptide TP508 in the situation of a high energy fracture can promote fracture healing and reduce the potential complications such as muscle fibrosis and fracture delayed or non-union.

  10. Career Preparedness and School Achievement of Portuguese Children: Longitudinal Trend Articulations

    Directory of Open Access Journals (Sweden)

    Maria do Céu Taveira

    2017-04-01

    Full Text Available Social Cognitive Career Theory suggests that students' preparedness for the school-to-work transition is a developmental process. Middle school children explore various careers, obtain feedback about their academic progress, and develop career self-efficacy and outcome expectations. These processes advance provisional educational/occupational goals. The literature has suggested articulations between career and academic development and how both vary across demographic characteristics, but longitudinal studies linking these processes are scarce. This study tested articulations between career preparedness and academic achievement during middle school years and employed gender and geographical location as potential moderators affecting the linkage between career and school domains. Participants included 429 children (47.8% girls from northern (69.5% and central Portugal (30.5% followed across four occasions of measurement (MageWave1 = 10.23, SD = 0.50. Data was collected with school records, the Multidimensional Scales of Perceived Self-Efficacy, Career Exploratory Outcome Expectations Scale, Childhood Career Exploration Inventory and Childhood Career Development Scale. Average and orthnormalized linear, quadratic and cubic trends were computed. Pearson correlation coefficients suggested positive and statistically significant associations between career exploratory outcome expectations and academic achievement average trends. Career planning and self-efficacy expectations were negatively associated with academic achievement quadratic trends. Multiple linear regression models suggested that career exploratory outcome expectations and career planning were respectively statistically significant predictors of the average and quadratic trends of academic achievement. Gender moderated the association between the career variables and academic achievement linear trends as well as the relation of career planning and self-efficacy with academic achievement

  11. The Effect of Pender's Health Promotion Model in Improving the Nutritional Behavior of Overweight and Obese Women.

    Science.gov (United States)

    Khodaveisi, Masoud; Omidi, Afsar; Farokhi, Shima; Soltanian, Ali Reza

    2017-04-01

    Changes in lifestyle and eating habits have put women at risk of obesity and overweight more than ever. This aim of this study was to investigate the effect of Pender's Health Promotion Model (HPM) to improve the nutritional behavior of overweight and obese women admitted to Fatemiyeh Hospital clinics in Hamadan, west Iran in 2015. In this quasi-experimental study, 108 eligible women were selected and randomly assigned to two groups: one experimental and one control. Data were gathered using three questionnaires: demographics, Pender's HPM constructs, and nutritional behavior. The questionnaires were filled out by both groups as pre-test and two months later. A Pender's HPM-based intervention was conducted for the experimental group. The data were analyzed by paired and independent t-tests, ANCOVA, and Spearmans' correlation coefficient in SPSS/16. The level of significance was considered to be educative model can be used by healthcare providers to improve the nutritional and other health promoting behaviors.

  12. Articulation of speech sounds of Serbian language in children aged six to eight

    Directory of Open Access Journals (Sweden)

    Mihajlović Biljana

    2015-01-01

    Full Text Available Introduction. Phonetic and phonological system of the healthy members of one linguistic community is fully formed around 8 years of age. The auditory and articulatory habits are established with age and tend to be more difficult to be upgraded and completed later. Material and Methods. The research was done as a cross-sectional study, conducted at the preschool institution “Radosno detinjstvo” and primary school “Branko Radičević” in Novi Sad. It included 66 children of both genders, aged 6 to 8. The quality of articulation was determined according to the Global Articulation Test by working with each child individually. Results. In each individual vowel, plosive, nasal, lateral and fricative, the quality of articulation was statistically significantly better in the first graders compared to the preschool children (p<0.01. In each affricate, except for the sound /ć/, the quality of articulation was statistically significantly better in the first graders than in the preschool children (p<0.01. The quality of articulation of all speech sounds was statistically significantly better in the first graders than in the preschool children (p<0.01. Discussion and Conclusion. The most common disorder of articulation is distortion, while only substitution and substitution associated with distortion are less common. Omission does not occur in children from 6 to 8 years of age. Girls have slightly better quality of articulation. The articulatory disorders are more common in preschool children than in children who are in the first grade of primary school. The most commonly mispronounced sounds belong to the group of affricates and fricatives.

  13. Modelling innovative interventions for optimising healthy lifestyle promotion in primary health care: "Prescribe Vida Saludable" phase I research protocol

    OpenAIRE

    Pombo Haizea; Cortada Josep M; Grandes Gonzalo; Sanchez Alvaro; Balague Laura; Calderon Carlos

    2009-01-01

    Abstract Background The adoption of a healthy lifestyle, including physical activity, a balanced diet, a moderate alcohol consumption and abstinence from smoking, are associated with large decreases in the incidence and mortality rates for the most common chronic diseases. That is why primary health care (PHC) services are trying, so far with less success than desirable, to promote healthy lifestyles among patients. The objective of this study is to design and model, under a participative col...

  14. Modelling innovative interventions for optimising healthy lifestyle promotion in primary health care: "prescribe Vida Saludable" phase I research protocol.

    Science.gov (United States)

    Sanchez, Alvaro; Grandes, Gonzalo; Cortada, Josep M; Pombo, Haizea; Balague, Laura; Calderon, Carlos

    2009-06-18

    The adoption of a healthy lifestyle, including physical activity, a balanced diet, a moderate alcohol consumption and abstinence from smoking, are associated with large decreases in the incidence and mortality rates for the most common chronic diseases. That is why primary health care (PHC) services are trying, so far with less success than desirable, to promote healthy lifestyles among patients. The objective of this study is to design and model, under a participative collaboration framework between clinicians and researchers, interventions that are feasible and sustainable for the promotion of healthy lifestyles in PHC. Phase I formative research and a quasi-experimental evaluation of the modelling and planning process will be undertaken in eight primary care centres (PCCs) of the Basque Health Service--OSAKIDETZA, of which four centres will be assigned for convenience to the Intervention Group (the others being Controls). Twelve structured study, discussion and consensus sessions supported by reviews of the literature and relevant documents, will be undertaken throughout 12 months. The first four sessions, including a descriptive strategic needs assessment, will lead to the prioritisation of a health promotion aim in each centre. In the remaining eight sessions, collaborative design of intervention strategies, on the basis of a planning process and pilot trials, will be carried out. The impact of the formative process on the practice of healthy lifestyle promotion, attitude towards health promotion and other factors associated with the optimisation of preventive clinical practice will be assessed, through pre- and post-programme evaluations and comparisons of the indicators measured in professionals from the centres assigned to the Intervention or Control Groups. There are four necessary factors for the outcome to be successful and result in important changes: (1) the commitment of professional and community partners who are involved; (2) their competence for

  15. Real-time localization of articulated surgical instruments in retinal microsurgery.

    Science.gov (United States)

    Rieke, Nicola; Tan, David Joseph; Amat di San Filippo, Chiara; Tombari, Federico; Alsheakhali, Mohamed; Belagiannis, Vasileios; Eslami, Abouzar; Navab, Nassir

    2016-12-01

    Real-time visual tracking of a surgical instrument holds great potential for improving the outcome of retinal microsurgery by enabling new possibilities for computer-aided techniques such as augmented reality and automatic assessment of instrument manipulation. Due to high magnification and illumination variations, retinal microsurgery images usually entail a high level of noise and appearance changes. As a result, real-time tracking of the surgical instrument remains challenging in in-vivo sequences. To overcome these problems, we present a method that builds on random forests and addresses the task by modelling the instrument as an articulated object. A multi-template tracker reduces the region of interest to a rectangular area around the instrument tip by relating the movement of the instrument to the induced changes on the image intensities. Within this bounding box, a gradient-based pose estimation infers the location of the instrument parts from image features. In this way, the algorithm does not only provide the location of instrument, but also the positions of the tool tips in real-time. Various experiments on a novel dataset comprising 18 in-vivo retinal microsurgery sequences demonstrate the robustness and generalizability of our method. The comparison on two publicly available datasets indicates that the algorithm can outperform current state-of-the art. Copyright © 2016. Published by Elsevier B.V.

  16. “A memorable consultation”: Writing reflective accounts articulates students’ learning in general practice

    Science.gov (United States)

    Svenberg, Kristian; Wahlqvist, Mats; Mattsson, Bengt

    2007-01-01

    Objectives To explore and analyse students’ learning experiences of a memorable consultation during a final-year attachment in general practice. Setting After a two-week primary care attachment in the undergraduate curriculum, students were invited to write a reflective account of a memorable consultation. Design A total of 52 reflective accounts were read and processed according to qualitative content analysis. Credibility of the analysis was validated by two co-authors reading the descriptions separately and trustworthiness was tested at local seminars. Results Three main themes emerged. In “The person beyond symptoms” the students recognize the individual properties of a consultation. “Facing complexity” mirrors awareness of changing tracks in problem-solving and strategies of handling unclear conditions. “In search of a professional role” reflects the interest in role modelling and the relation to the supervisor. Conclusion Involving students in writing reflective accounts appears to stimulate them to articulate practice experiences of the consultation. PMID:17497483

  17. Promoting Healthy Work for Employees with Chronic Illness : Analysis of Models of Good Practice

    NARCIS (Netherlands)

    Dijkman, Anja; Have, Kristin ten; Gründemann, Rob; Wevers, Cees

    2012-01-01

    The ENWHP project and campaign Promoting Healthy Work for Employees with Chronic Illness (PH Work) should contribute towards the implementation of effective workplace health practices within corporate policies of enterprises in Europe. More specific the project should stimulate activities and polici

  18. Coaching Early Childhood Special Educators to Implement a Comprehensive Model for Promoting Young Children's Social Competence

    Science.gov (United States)

    Fox, Lise; Hemmeter, Mary; Snyder, Patricia; Binder, Denise Perez; Clarke, Shelley

    2011-01-01

    Growing evidence suggests the importance of practitioners implementing promotion, prevention, and intervention practices to foster children's social-emotional competence and address challenging behavior within schools. Limited research exists, however, on how to support teachers of school-age children to implement with fidelity comprehensive…

  19. Numerical Modelling with Spreadsheets as a Means to Promote STEM to High School Students

    Science.gov (United States)

    Benacka, Jan

    2016-01-01

    The article gives an account of an experiment in which sixty-eight high school students of age 16 - 19 developed spreadsheet applications that simulated fall and projectile motion in the air. The students applied the Euler method to solve the governing differential equations. The aim was to promote STEM to the students and motivate them to study…

  20. Promoting Entrepreneurial Culture in the University: The Institutional Collaborative Model at the Universidad Autonoma de Madrid

    Science.gov (United States)

    de Pablo, Isidro; Alfaro, Fernando; Rodriguez, Miriam; Valdes, Esperanza

    2011-01-01

    This paper presents a case of collaboration between different types of public services and the private sector for the promotion of an entrepreneurial culture. This collaboration is achieved by means of a centre established and developed by the Universidad Autonoma de Madrid, the Centro de Iniciativas Emprendedoras (the Centre for Entrepreneurial…

  1. Mathematics Instructional Model Based on Realistic Mathematics Education to Promote Problem Solving Ability at Junior High School Padang

    Directory of Open Access Journals (Sweden)

    Edwin Musdi

    2016-02-01

    Full Text Available This research aims to develop a mathematics instructional model based realistic mathematics education (RME to promote students' problem-solving abilities. The design research used Plomp models, which consists of preliminary phase, development or proto-typing phase and assessment phase.  At this study, only the first two phases conducted. The first phase, a preliminary investigation, carried out with a literature study to examine the theory-based instructional learning RME model, characteristics of learners, learning management descriptions by junior high school mathematics teacher and relevant research. The development phase is done by developing a draft model (an early prototype model that consists of the syntax, the social system, the principle of reaction, support systems, and the impact and effects of instructional support. Early prototype model contain a draft model, lesson plans, worksheets, and assessments. Tesssmer formative evaluation model used to revise the model. In this study only phase of one to one evaluation conducted. In the ppreliminary phase has produced a theory-based learning RME model, a description of the characteristics of learners in grade VIII Junior High School Padang and the description of teacher teaching in the classroom. The result showed that most students were still not be able to solve the non-routine problem. Teachers did not optimally facilitate students to develop problem-solving skills of students. It was recommended that the model can be applied in the classroom.

  2. Mathematics Instructional Model Based on Realistic Mathematics Education to Promote Problem Solving Ability at Junior High School Padang

    Directory of Open Access Journals (Sweden)

    Edwin Musdi

    2016-02-01

    Full Text Available This research aims to develop a mathematics instructional model based realistic mathematics education (RME to promote students' problem-solving abilities. The design research used Plomp models, which consists of preliminary phase, development or proto-typing phase and assessment phase.  At this study, only the first two phases conducted. The first phase, a preliminary investigation, carried out with a literature study to examine the theory-based instructional learning RME model, characteristics of learners, learning management descriptions by junior high school mathematics teacher and relevant research. The development phase is done by developing a draft model (an early prototype model that consists of the syntax, the social system, the principle of reaction, support systems, and the impact and effects of instructional support. Early prototype model contain a draft model, lesson plans, worksheets, and assessments. Tesssmer formative evaluation model used to revise the model. In this study only phase of one to one evaluation conducted. In the ppreliminary phase has produced a theory-based learning RME model, a description of the characteristics of learners in grade VIII Junior High School Padang and the description of teacher teaching in the classroom. The result showed that most students were still not be able to solve the non-routine problem. Teachers did not optimally facilitate students to develop problem-solving skills of students. It was recommended that the model can be applied in the classroom.

  3. DSS colitis promotes tumorigenesis and fibrogenesis in a choline-deficient high-fat diet-induced NASH mouse model.

    Science.gov (United States)

    Achiwa, Koichi; Ishigami, Masatoshi; Ishizu, Yoji; Kuzuya, Teiji; Honda, Takashi; Hayashi, Kazuhiko; Hirooka, Yoshiki; Katano, Yoshiaki; Goto, Hidemi

    2016-01-29

    Nonalcoholic steatohepatitis (NASH) patients progress to liver cirrhosis and even hepatocellular carcinoma (HCC). Several lines of evidence indicate that accumulation of lipopolysaccharide (LPS) and disruption of gut microbiota play contributory roles in HCC. Moreover, in a dextran sodium sulfate (DSS)-induced colitis model in mice, a high-fat diet increases portal LPS level and promotes hepatic inflammation and fibrosis. However, this diet-induced NASH model requires at least 50 weeks for carcinogenesis. In this study, we sought to determine whether increased intestinal permeability would aggravate liver inflammation and fibrosis and accelerate tumorigenesis in a diet-induced NASH model. Mice were fed a choline-deficient high-fat (CDHF) diet for 4 or 12 weeks. The DSS group was fed CDHF and intermittently received 1% DSS in the drinking water. Exposure to DSS promoted mucosal changes such as crypt loss and increased the number of inflammatory cells in the colon. In the DSS group, portal LPS levels were elevated at 4 weeks, and the proportions of Clostridium cluster XI in the fecal microbiota were elevated. In addition, levels of serum transaminase, number of lobular inflammatory cells, F4/80 staining-positive area, and levels of inflammatory cytokines were all elevated in the DSS group. Liver histology in the DSS group revealed severe fibrosis at 12 weeks. Liver tumors were detected in the DSS group at 12 weeks, but not in the other groups. Thus, DSS administration promoted liver tumors in a CDHF diet-induced NASH mouse over the short term, suggesting that the induction of intestinal inflammation and gut disruption of microbiota in NASH promote hepatic tumorigenesis.

  4. In-Flight Position Calibration of the Cassini Articulated Reaction Wheel Assembly

    Science.gov (United States)

    Brown, Todd S.

    2012-01-01

    NASA's long-lived Cassini-Huygens spacecraft is currently in its 14th year of flight and in the midst of its second, and final, extended mission. Cassini is a massive interplanetary spacecraft that is three axis stabilized and can maintain attitude control using either its reaction control system thrusters or using reaction wheel control. Cassini has four identical reaction wheels, of which three are mutually orthogonal and have a fixed orientation. The fourth reaction wheel has an articulation motor that allows this reaction wheel to be aligned with the momentum direction of any of the other three fixed reaction wheels. The articulation motor allows this reaction wheel to be used as a replacement for any of the other three wheels without any performance degradation. However, due to limitations in the design of this backup system, there are few telemetric indications of the orientation of this reaction wheel following an articulation. This investigation serves to outline the procedures that have been developed by the Cassini Attitude and Articulation Control Subsystem to calibrate the position of the articulated reaction wheel assembly in the event that the momentum direction of this reaction wheel must be reoriented.

  5. The brief history of articulator%牙合架的发展简史

    Institute of Scientific and Technical Information of China (English)

    吴国锋

    2016-01-01

    This article introduces the origin of articulator and its development process from humble to perfect in the past more than 200 years. The development of articulator is divided into 3 historical periods by the author:Early articulator,modern articulator and contemporary articula-tor.Meanwhile,the detailed basic design principle of articulator,the development of condylar guidance and incisal guidance are explained.%该文以历史时间为轴,详细讲述了牙合架从无到有、从简陋到完善的200多年发展过程。作者将牙合架发展史分为早期牙合架、近代牙合架和现代牙合架3个时期,详细讲解了牙合架的基本设计原理,并列举了髁导、切导等重要牙合架结构的演变由来。

  6. Genetic algorithm trajectory plan optimization for EAMA: EAST Articulated Maintenance Arm

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Jing, E-mail: wujing@ipp.ac.cn [Institute of Plasma Physics, Chinese Academy of Sciences, 350 Shushanhu Rd., Hefei, Anhui (China); Lappeenranta University of Technology, Skinnarilankatu 34, Lappeenranta (Finland); Wu, Huapeng [Lappeenranta University of Technology, Skinnarilankatu 34, Lappeenranta (Finland); Song, Yuntao; Cheng, Yong; Zhao, Wenglong [Institute of Plasma Physics, Chinese Academy of Sciences, 350 Shushanhu Rd., Hefei, Anhui (China); Wang, Yongbo [Lappeenranta University of Technology, Skinnarilankatu 34, Lappeenranta (Finland)

    2016-11-01

    Highlights: • A redundant 10-DOF serial-articulated robot for EAST assembly and maintains is presented. • A trajectory optimization algorithm of the robot is developed. • A minimum jerk objective is presented to suppress machining vibration of the robot. - Abstract: EAMA (EAST Articulated Maintenance Arm) is an articulated serial manipulator with 7 degrees of freedom (DOF) articulated arm followed by 3-DOF gripper, total length is 8.867 m, works in experimental advanced superconductor tokamak (EAST) vacuum vessel (VV) to perform blanket inspection and remote maintenance tasks. This paper presents a trajectory optimization method which aims to pursue the 7-DOF articulated arm a stable movement, which keeps the mounted inspection camera anti-vibration. Based on dynamics analysis, trajectory optimization algorithm adopts multi-order polynomial interpolation in joint space and high order geometry Jacobian transform. The object of optimization algorithm is to suppress end-effector movement vibration by minimizing jerk RMS (root mean square) value. The proposed solution has such characteristics which can satisfy kinematic constraints of EAMA’s motion and ensure the arm running under the absolute values of velocity, acceleration and jerk boundaries. GA (genetic algorithm) is employed to find global and robust solution for this problem.

  7. Fluoxetine treatment promotes functional recovery in a rat model of cervical spinal cord injury

    Science.gov (United States)

    Scali, Manuela; Begenisic, Tatjana; Mainardi, Marco; Milanese, Marco; Bonifacino, Tiziana; Bonanno, Giambattista; Sale, Alessandro; Maffei, Lamberto

    2013-01-01

    Spinal cord injury (SCI) is a severe condition leading to enduring motor deficits. When lesions are incomplete, promoting spinal cord plasticity might be a useful strategy to elicit functional recovery. Here we investigated whether long-term fluoxetine administration in the drinking water, a treatment recently demonstrated to optimize brain plasticity in several pathological conditions, promotes motor recovery in rats that received a C4 dorsal funiculus crush. We show that fluoxetine administration markedly improved motor functions compared to controls in several behavioral paradigms. The improved functional effects correlated positively with significant sprouting of intact corticospinal fibers and a modulation of the excitation/inhibition balance. Our results suggest a potential application of fluoxetine treatment as a non invasive therapeutic strategy for SCI-associated neuropathologies. PMID:23860568

  8. Aggressiveness of human melanoma xenograft models is promoted by aneuploidy-driven gene expression deregulation

    OpenAIRE

    Mathieu, Véronique; Pirker, Christine; Schmidt, Wolfgang M.; Spiegl-Kreinecker, Sabine; Lötsch, Daniela; Heffeter, Petra; Hegedus, Balazs; Grusch, Michael; Kiss, Robert; Berger, Walter

    2012-01-01

    Melanoma is a devastating skin cancer characterized by distinct biological subtypes. Besides frequent mutations in growth- and survival-promoting genes like BRAF and NRAS, melanomas additionally harbor complex non-random genomic alterations. Using an integrative approach, we have analysed genomic and gene expression changes in human melanoma cell lines (N=32) derived from primary tumors and various metastatic sites and investigated the relation to local growth aggressiveness as xenografts in ...

  9. NASA's Earth Observations Commercialization Applications Program: A model for government promotion of commercial space opportunities

    Science.gov (United States)

    Macauley, Molly K.

    1995-01-01

    The role of government in promoting space commerce is a topic of discussion in every spacefaring nation. This article describes a new approach to government intervention which, based on its five-year track record, appears to have met with success. The approach, developed in NASA's Earth Observations Commercialization Application Program (EOCAP), offer several lessons for effective government sponsorship of commercial space development in general and of commercial remote sensing in particular.

  10. Type-dependent irreversible stochastic spin models for genetic regulatory networks at the level of promotion-inhibition circuitry

    Science.gov (United States)

    Mendonça, J. Ricardo G.; de Oliveira, Mário J.

    2015-12-01

    We describe an approach to model genetic regulatory networks at the level of promotion-inhibition circuitry through a class of stochastic spin models that includes spatial and temporal density fluctuations in a natural way. The formalism can be viewed as an agent-based model formalism with agent behaviour ruled by a classical spin-like pseudo-Hamiltonian playing the role of a local, individual objective function. A particular but otherwise generally applicable choice for the microscopic transition rates of the models also makes them of independent interest. To illustrate the formalism, we investigate (by Monte Carlo simulations) some stationary state properties of the repressilator, a synthetic three-gene network of transcriptional regulators that possesses oscillatory behaviour.

  11. An evaluation of a model for the systematic documentation of hospital based health promotion activities: results from a multicentre study

    DEFF Research Database (Denmark)

    Tønnesen, Hanne; Christensen, Mette E; Groene, Oliver;

    2007-01-01

    The first step of handling health promotion (HP) in Diagnosis Related Groups (DRGs) is a systematic documentation and registration of the activities in the medical records. So far the possibility and tradition for systematic registration of clinical HP activities in the medical records and in pat......The first step of handling health promotion (HP) in Diagnosis Related Groups (DRGs) is a systematic documentation and registration of the activities in the medical records. So far the possibility and tradition for systematic registration of clinical HP activities in the medical records...... of two parts; first part includes motivational counselling (7 codes) and the second part comprehends intervention, rehabilitation and after treatment (8 codes).The objective was to evaluate in an international study the usefulness, applicability and sufficiency of a simple model for the systematic...

  12. Comparison of mechanical properties of silicone and PVC (polyvinylchloride) cosmetic gloves for articulating hand prostheses.

    Science.gov (United States)

    Smit, Gerwin; Plettenburg, Dick H

    2013-01-01

    Current articulating electric and body-powered hands have a lower pinch force (15-34 N) than electric hands with stiff fingers (55-100 N). The cosmetic glove, which covers a hand prosthesis, negatively affects the mechanical efficiency of a prosthesis. The goal of this study is to mechanically compare polyvinylchloride (PVC) and silicone cosmetic gloves and quantify the stiffness of the finger joints, the required actuation energy, and the energy dissipation during joint articulation. Six cosmetic gloves, identical in size but made from different materials, were mechanically tested: three PVC and three silicone. The silicone gloves required less work and dissipated less energy during flexing. They also had a lower joint stiffness and required a lower maximum joint torque. Based on energy requirements, joint stiffness, and required joint torque, the tested silicone glove is most suitable for application on an articulating hand prosthesis.

  13. Development of a Wave Energy -Responsive Self-Actuated Blade Articulation Mechanism for an OWC Turbine

    Energy Technology Data Exchange (ETDEWEB)

    Francis A. Di Bella

    2010-06-01

    The Phase I SBIR effort completed the feasibility design, fabrication, and wind tunnel testing of a self-actuated blade articulation mechanism that uses a torsion bar and a lightweight airfoil to affect the articulation of the Wells airfoil. The articulation is affected only by the air stream incident on the airfoil. The self-actuating blade eliminates the complex and costly linkage mechanism that is now needed to perform this function on either a variable pitch Wells-type or Dennis-Auld air turbine. Using the results reported by independent researchers, the projected improvement in the Wells-type turbine efficiency is 20-40%, in addition to an increase in the operating air flow range by 50-100%, therefore enabling a smaller or slower single turbine to be used.

  14. Acoustic Cues to Fricatives Place of Articulation Produced in Moroccan Dialect

    Directory of Open Access Journals (Sweden)

    Leila Elmazouzi

    2014-11-01

    Full Text Available The aim of the present study is to examine acoustic characteristics of Moroccan fricatives in order to find invariant cues that classify fricatives into their place of articulation. Fricative consonants of Moroccan Arabic dialect were elicited from 8 adult speakers (4 male and 4 female in 3 vowel contexts (/i, a, u/. The cues investigated included temporal measurement (duration of fricative consonant and formant information at fricative-vowel transition (F1 and F2 at vowel onset and locus equation. The effects of voicing, speaker’s gender and post-fricative vowel on both formants onset values and locus equations were investigated. The results obtained showed that F1 onset values differentiated voiceless from voiced fricatives. F2 onset values distinguished fricatives in term of place of articulation. The locus equation slope and intercept differentiated voiceless from voiced fricative and distinguished clearly palatal fricatives from the other places of articulation

  15. Articulation and Hegemony: Tensions between the particular and the universal in the experience of struggle

    Directory of Open Access Journals (Sweden)

    Parra, Alejandra

    2008-05-01

    Full Text Available Difference in the experiences of social struggle, in our country and throughout Latin America and the world, urgently need explication or, as we would say, articulation. However, we are aware that there are dangers in articulating too simple and unfying an account of the great diversity of identities and experiences that characterize current social struggles.We begin by specifying some of our dissatisfactions and disagreements with certain ways of approaching - or avoiding - the problems of articulation and hegemony. We identify those authors who we consider to be central to this subject, and explore their work. We then reflect on our conversations with people who took part in the processes of social mobilization which occurred in Argentina from December, 2001 onwards

  16. Design of planar articulated mechanisms using branch and bound

    DEFF Research Database (Denmark)

    Stolpe, Mathias; Kawamoto, Atsushi

    2004-01-01

    This paper considers an optimization model and a solution method for the design of two-dimensional mechanical mechanisms. The mechanism design problem is modeled as a nonconvex mixed integer program which allows the optimal topology and geometry of the mechanism to be determined simultaneously. T...

  17. Design of planar articulated mechanisms using branch and bound

    DEFF Research Database (Denmark)

    Stolpe, Mathias; Kawamoto, Atsushi

    2005-01-01

    This paper considers an optimization model and a solution method for the design of two-dimensional mechanical mechanisms. The mechanism design problem is modeled as a nonconvex mixed integer program which allows the optimal topology and geometry of the mechanism to be determined simultaneously. T...

  18. Scaling up of breastfeeding promotion programs in low- and middle-income countries: the "breastfeeding gear" model.

    Science.gov (United States)

    Pérez-Escamilla, Rafael; Curry, Leslie; Minhas, Dilpreet; Taylor, Lauren; Bradley, Elizabeth

    2012-11-01

    Breastfeeding (BF) promotion is one of the most cost-effective interventions to advance mother-child health. Evidence-based frameworks and models to promote the effective scale up and sustainability of BF programs are still lacking. A systematic review of peer-reviewed and gray literature reports was conducted to identify key barriers and facilitators for scale up of BF programs in low- and middle-income countries. The review identified BF programs located in 28 countries in Africa, Latin America and the Caribbean, and Asia. Study designs included case studies, qualitative studies, and observational quantitative studies. Only 1 randomized, controlled trial was identified. A total of 22 enabling factors and 15 barriers were mapped into a scale-up framework termed "AIDED" that was used to build the parsimonious breastfeeding gear model (BFGM). Analogous to a well-oiled engine, the BFGM indicates the need for several key "gears" to be working in synchrony and coordination. Evidence-based advocacy is needed to generate the necessary political will to enact legislation and policies to protect, promote, and support BF at the hospital and community levels. This political-policy axis in turn drives the resources needed to support workforce development, program delivery, and promotion. Research and evaluation are needed to sustain the decentralized program coordination "gear" required for goal setting and system feedback. The BFGM helps explain the different levels of performance in national BF outcomes in Mexico and Brazil. Empirical research is recommended to further test the usefulness of the AIDED framework and BFGM for global scaling up of BF programs.

  19. Ginsenoside Rg1 promotes peripheral nerve regeneration in rat model of nerve crush injury.

    Science.gov (United States)

    Ma, Junxiong; Li, Wenxian; Tian, Ruifeng; Lei, Wei

    2010-07-05

    Searching for effective drugs which are capable of promoting nerve regeneration after nerve injuries has gained extensive attention. Ginsenoside Rg1 (GRg1) is one of the bioactive compounds extracted from ginseng. GRg1 has been shown to be neuroprotective in many in vitro studies, which raises the possibility of using GRg1 as a neuroprotective agent after nerve injuries. However, such a possibility has never been tested in in vivo studies. The present study was designed to investigate the efficacy of GRg1 in promoting nerve regeneration after nerve crush injury in rats. All rats were randomly divided into four groups (n=8 in each group) after crush injury and were intraperitoneally administrated daily for 4 weeks with 1mg/kg, or 5mg/kg GRg1 (low or high dose GRg1 groups), or 100mug/kg mecobalamin or normal saline, respectively. The axonal regeneration was investigated by retrograde labeling and morphometric analysis. The motor functional recovery was evaluated by electrophysiological studies, behavioral tests and histological appearance of the target muscles. Our data showed that high dose GRg1 achieved better axonal regeneration and functional recovery than those achieved by low dose GRg1 and mecobalamin. The final outcome of low dose GRg1 and mecobalamin was similar in both morphological and functional items, which was significantly better than that in saline group. These findings show that GRg1 is capable of promoting nerve regeneration after nerve injuries, suggesting the possibility of developing GRg1 a neuroprotective drug for peripheral nerve repair applications.

  20. International Combined Orthopaedic Research Societies: A model for international collaboration to promote orthopaedic and musculoskeletal research

    Directory of Open Access Journals (Sweden)

    Theodore Miclau

    2014-10-01

    Full Text Available In October 2013, the International Combined Orthopaedic Research Societies (ICORS; http://i-cors.org was founded with inaugural member organisations from the previous Combined Orthopaedic Research Society, which had sponsored combined meetings for more than 2 decades. The ICORS is dedicated to the stimulation of orthopaedic and musculoskeletal research in fields such as biomedical engineering, biology, chemistry, and veterinary and human clinical research. The ICORS seeks to facilitate communication with member organisations to enhance international research collaborations and to promote the development of new international orthopaedic and musculoskeletal research organisations. Through new categories of membership, the ICORS represents the broadest coalition of orthopaedic research organisations globally.